L-pipecolate oxidase activity

Catalysis of the reaction: L-pipecolate + O2 = 2,3,4,5-tetrahydropyridine-2-carboxylate + H2O2 + H+. Delta1-piperideine-6-carboxylate is also known as 2,3,4,5-tetrahydropyridine-2-carboxylate.


L-lysine catabolic process to acetyl-CoA via L-pipecolate

biolink:BiologicalProcess biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:Occurrent biolink:OntologyClass biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

The chemical reactions and pathways resulting in the breakdown of L-lysine into other compounds, including acetyl-CoA, via the intermediate L-pipecolate.


DOK5_HUMAN Docking protein 5 (sprot)

A docking protein 5 that is encoded in the genome of human.


GMIP_HUMAN GEM-interacting protein (sprot)

A GEM-interacting protein that is encoded in the genome of human.


GCNT4_HUMAN Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 4 (sprot)

A beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 4 that is encoded in the genome of human.


NTRI_HUMAN Neurotrimin (sprot)

A neurotrimin that is encoded in the genome of human.


CLC1B_HUMAN C-type lectin domain family 1 member B (sprot)

A C-type lectin domain family 1 member B that is encoded in the genome of human.


LUZP4_HUMAN Leucine zipper protein 4 (sprot)

A leucine zipper protein 4 that is encoded in the genome of human.


PP4RL_HUMAN Putative serine/threonine-protein phosphatase 4 regulatory subunit 1-like (sprot)

A putative serine/threonine-protein phosphatase 4 regulatory subunit 1-like that is encoded in the genome of human.


DLGP2_HUMAN Disks large-associated protein 2 (sprot)

A disks large-associated protein 2 that is encoded in the genome of human.


YN010_HUMAN Putative uncharacterized protein PRO2829 (sprot)


TAAR3_HUMAN Putative trace amine-associated receptor 3 (sprot)

A putative trace amine-associated receptor 3 that is encoded in the genome of human.


trace-amine receptor activity

biolink:MolecularActivity biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:Occurrent biolink:OntologyClass biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

Combining with a trace amine to initiate a change in cell activity. Trace amines are biogenic amines that are synthesized from aromatic amino acids and are substrates for monoamine oxidase, and are therefore detectable only at trace levels in mammals.


TAAR2_HUMAN Trace amine-associated receptor 2 (sprot)

A trace amine-associated receptor 2 that is encoded in the genome of human.


VPS54_HUMAN Vacuolar protein sorting-associated protein 54 (sprot)

A vacuolar protein sorting-associated protein 54 that is encoded in the genome of human.


OR1A1_HUMAN Olfactory receptor 1A1 (sprot)

An olfactory receptor 1A1 that is encoded in the genome of human.


MDFIC_HUMAN MyoD family inhibitor domain-containing protein (sprot)

A MyoD family inhibitor domain-containing protein that is encoded in the genome of human.


RPA12_HUMAN DNA-directed RNA polymerase I subunit RPA12 (sprot)

A DNA-directed RNA polymerase I subunit RPA12 that is encoded in the genome of human.


ARP3B_HUMAN Actin-related protein 3B (sprot)

An actin-related protein 3B that is encoded in the genome of human.


CSC1_HUMAN Calcium permeable stress-gated cation channel 1 (sprot)

A calcium permeable stress-gated cation channel 1 that is encoded in the genome of human.


SIRPG_HUMAN Signal-regulatory protein gamma (sprot)

A signal-regulatory protein gamma that is encoded in the genome of human.


PIM2_HUMAN Serine/threonine-protein kinase pim-2 (sprot)

A serine/threonine-protein kinase Pim-2 that is encoded in the genome of human.


CAMP3_HUMAN Calmodulin-regulated spectrin-associated protein 3 (sprot)

A calmodulin-regulated spectrin-associated protein 3 that is encoded in the genome of human.


PHRF1_HUMAN PHD and RING finger domain-containing protein 1 (sprot)

A PHD and RING finger domain-containing protein 1 that is encoded in the genome of human.


ZBTB4_HUMAN Zinc finger and BTB domain-containing protein 4 (sprot)

A zinc finger and BTB domain-containing protein 4 that is encoded in the genome of human.


methyl-CpNpG binding

Binding to a methylated cytosine/unspecified/guanine trinucleotide.


CACO1_HUMAN Calcium-binding and coiled-coil domain-containing protein 1 (sprot)

A calcium-binding and coiled-coil domain-containing protein 1 that is encoded in the genome of human.


HCN3_HUMAN Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 (sprot)

A potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 that is encoded in the genome of human.


CC180_HUMAN Coiled-coil domain-containing protein 180 (sprot)

A protein that is a translation product of the CCDC180 gene in human.


WHRN_HUMAN Whirlin (sprot)

A whirlin that is encoded in the genome of human.


BTBD7_HUMAN BTB/POZ domain-containing protein 7 (sprot)

A BTB/POZ domain-containing protein 7 that is encoded in the genome of human.


CEP72_HUMAN Centrosomal protein of 72 kDa (sprot)

A centrosomal protein of 72 kDa that is encoded in the genome of human.


PLCE1_HUMAN 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 (sprot)

A 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 that is encoded in the genome of human.


POGK_HUMAN Pogo transposable element with KRAB domain (sprot)

A pogo transposable element with KRAB domain that is encoded in the genome of human.


ZSWM5_HUMAN Zinc finger SWIM domain-containing protein 5 (sprot)

A zinc finger SWIM domain-containing protein 5 that is encoded in the genome of human.


COKA1_HUMAN Collagen alpha-1(XX) chain (sprot)

A collagen alpha-1(XX) chain that is encoded in the genome of human.


DAPLE_HUMAN Protein Daple (sprot)

A protein Daple that is encoded in the genome of human.


DYH2_HUMAN Dynein axonemal heavy chain 2 (sprot)

A dynein axonemal heavy chain 2 that is encoded in the genome of human.


RHG23_HUMAN Rho GTPase-activating protein 23 (sprot)

A Rho GTPase-activating protein 23 that is encoded in the genome of human.


CNTN3_HUMAN Contactin-3 (sprot)

A contactin-3 that is encoded in the genome of human.


AT10D_HUMAN Phospholipid-transporting ATPase VD (sprot)

A phospholipid-transporting ATPase VD that is encoded in the genome of human.


NYAP2_HUMAN Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 2 (sprot)

A neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 2 that is encoded in the genome of human.


ZFAT_HUMAN Zinc finger protein ZFAT (sprot)

A zinc finger protein ZFAT that is encoded in the genome of human.


LRFN1_HUMAN Leucine-rich repeat and fibronectin type III domain-containing protein 1 (sprot)

A leucine-rich repeat and fibronectin type III domain-containing protein 1 that is encoded in the genome of human.


STIM2_HUMAN Stromal interaction molecule 2 (sprot)

A stromal interaction molecule 2 that is encoded in the genome of human.


VPS18_HUMAN Vacuolar protein sorting-associated protein 18 homolog (sprot)

A vacuolar protein sorting-associated protein 18 that is encoded in the genome of human.


ZN492_HUMAN Zinc finger protein 492 (sprot)

A zinc finger protein 492 that is encoded in the genome of human.


RCC2_HUMAN Protein RCC2 (sprot)

A protein RCC2 that is encoded in the genome of human.


chromosome passenger complex localization to kinetochore

A cellular protein complex localization that acts on a chromosome passenger complex; as a result, the complex is transported to, or maintained in, a specific location at the kinetochore. A chromosome passenger complex is a protein complex that contains the BIR-domain-containing protein Survivin, Aurora B kinase, INCENP and Borealin, and coordinates various events based on its location to different structures during the course of mitosis.


chromosome, centromeric core domain

biolink:CellularComponent biolink:AnatomicalEntity biolink:OrganismalEntity biolink:BiologicalEntity biolink:NamedThing biolink:PhysicalEssence biolink:SubjectOfInvestigation biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

The innermost portion of the centromeric region of a chromosome, encompassing the core region of a chromosome centromere and the proteins that bind to it.


RELCH_HUMAN RAB11-binding protein RELCH (sprot)

A RAB11-binding protein RELCH that is encoded in the genome of human.


DIP2B_HUMAN Disco-interacting protein 2 homolog B (sprot)

A disco-interacting protein 2 homolog B that is encoded in the genome of human.


JCAD_HUMAN Junctional cadherin 5-associated protein (sprot)

A junctional cadherin 5-associated protein that is encoded in the genome of human.


MBD5_HUMAN Methyl-CpG-binding domain protein 5 (sprot)

A methyl-CpG-binding domain protein 5 that is encoded in the genome of human.


SLAI2_HUMAN SLAIN motif-containing protein 2 (sprot)

A SLAIN motif-containing protein 2 that is encoded in the genome of human.


TRM9B_HUMAN Probable tRNA methyltransferase 9B (sprot)

A probable tRNA methyltransferase 9B that is encoded in the genome of human.


TEN3_HUMAN Teneurin-3 (sprot)

A teneurin-3 that is encoded in the genome of human.


UBP36_HUMAN Ubiquitin carboxyl-terminal hydrolase 36 (sprot)

A ubiquitin carboxyl-terminal hydrolase 36 that is encoded in the genome of human.


FNIP2_HUMAN Folliculin-interacting protein 2 (sprot)

A folliculin-interacting protein 2 that is encoded in the genome of human.


BAHC1_HUMAN BAH and coiled-coil domain-containing protein 1 (sprot)

A BAH and coiled-coil domain-containing protein 1 that is encoded in the genome of human.


SEM5B_HUMAN Semaphorin-5B (sprot)

A semaphorin-5B that is encoded in the genome of human.


PAK5_HUMAN Serine/threonine-protein kinase PAK 5 (sprot)

A serine/threonine-protein kinase PAK 5 that is encoded in the genome of human.


BCCIP_HUMAN BRCA2 and CDKN1A-interacting protein (sprot)

A BRCA2 and CDKN1A-interacting protein that is encoded in the genome of human.


STK26_HUMAN Serine/threonine-protein kinase 26 (sprot)

A serine/threonine-protein kinase 26 that is encoded in the genome of human.


ARMX1_HUMAN Armadillo repeat-containing X-linked protein 1 (sprot)

An armadillo repeat-containing X-linked protein 1 that is encoded in the genome of human.


C5AR2_HUMAN C5a anaphylatoxin chemotactic receptor 2 (sprot)

A C5a anaphylatoxin chemotactic receptor 2 that is encoded in the genome of human.


HIG1B_HUMAN HIG1 domain family member 1B (sprot)

A HIG1 domain family member 1B that is encoded in the genome of human.


COPZ2_HUMAN Coatomer subunit zeta-2 (sprot)

A coatomer subunit zeta-2 that is encoded in the genome of human.


ABI3_HUMAN ABI gene family member 3 (sprot)

An ABI gene family member 3 that is encoded in the genome of human.


FPRP_HUMAN Prostaglandin F2 receptor negative regulator (sprot)

A prostaglandin F2 receptor negative regulator that is encoded in the genome of human.


CT2NL_HUMAN CTTNBP2 N-terminal-like protein (sprot)

A CTTNBP2 N-terminal-like protein that is encoded in the genome of human.


negative regulation of transmembrane transport

Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a solute from one side of a membrane to the other.


TM181_HUMAN Transmembrane protein 181 (sprot)

A transmembrane protein 181 that is encoded in the genome of human.


IBTK_HUMAN Inhibitor of Bruton tyrosine kinase (sprot)

An inhibitor of Bruton tyrosine kinase that is encoded in the genome of human.


CHD7_HUMAN Chromodomain-helicase-DNA-binding protein 7 (sprot)

A chromodomain-helicase-DNA-binding protein 7 that is encoded in the genome of human.


right ventricular compact myocardium morphogenesis

The process in which the anatomical structures of the right ventricular compact myocardium are generated and organized.


HTR5B_HUMAN HEAT repeat-containing protein 5B (sprot)

A HEAT repeat-containing protein 5B that is encoded in the genome of human.


DYH1_HUMAN Dynein axonemal heavy chain 1 (sprot)

A dynein axonemal heavy chain 1 that is encoded in the genome of human.


UNC79_HUMAN Protein unc-79 homolog (sprot)

A protein unc-79 homolog that is encoded in the genome of human.


KIF17_HUMAN Kinesin-like protein KIF17 (sprot)

A kinesin-like protein KIF17 that is encoded in the genome of human.


ZNFX1_HUMAN NFX1-type zinc finger-containing protein 1 (sprot)

An NFX1-type zinc finger-containing protein 1 that is encoded in the genome of human.


CHPF2_HUMAN Chondroitin sulfate glucuronyltransferase (sprot)

A chondroitin sulfate glucuronyltransferase that is encoded in the genome of human.


PCD10_HUMAN Protocadherin-10 (sprot)

A protocadherin-10 that is encoded in the genome of human.


MARH4_HUMAN E3 ubiquitin-protein ligase MARCHF4 (sprot)

An E3 ubiquitin-protein ligase MARCHF4 that is encoded in the genome of human.


RRBP1_HUMAN Ribosome-binding protein 1 (sprot)

A ribosome-binding protein 1 that is encoded in the genome of human.


STOX2_HUMAN Storkhead-box protein 2 (sprot)

A storkhead-box protein 2 that is encoded in the genome of human.


RHG20_HUMAN Rho GTPase-activating protein 20 (sprot)

A Rho GTPase-activating protein 20 that is encoded in the genome of human.


SI1L2_HUMAN Signal-induced proliferation-associated 1-like protein 2 (sprot)

A signal-induced proliferation-associated 1-like protein 2 that is encoded in the genome of human.


ZN319_HUMAN Zinc finger protein 319 (sprot)

A zinc finger protein 319 that is encoded in the genome of human.


AKIB1_HUMAN Ankyrin repeat and IBR domain-containing protein 1 (sprot)

An ankyrin repeat and IBR domain-containing protein 1 that is encoded in the genome of human.


KLH14_HUMAN Kelch-like protein 14 (sprot)

A kelch-like protein 14 that is encoded in the genome of human.


MAP10_HUMAN Microtubule-associated protein 10 (sprot)

A microtubule-associated protein 10 that is encoded in the genome of human.


KLHL8_HUMAN Kelch-like protein 8 (sprot)

A kelch-like protein 8 that is encoded in the genome of human.


CE126_HUMAN Centrosomal protein of 126 kDa (sprot)

A protein that is a translation product of the CEP126 gene in human.


IFT80_HUMAN Intraflagellar transport protein 80 homolog (sprot)

An intraflagellar transport protein 80 that is encoded in the genome of human.


UBP35_HUMAN Ubiquitin carboxyl-terminal hydrolase 35 (sprot)

A ubiquitin carboxyl-terminal hydrolase 35 that is encoded in the genome of human.


CPSF2_HUMAN Cleavage and polyadenylation specificity factor subunit 2 (sprot)

A cleavage and polyadenylation specificity factor subunit 2 that is encoded in the genome of human.


TUTLA_HUMAN Protein turtle homolog A (sprot)

A protein turtle homolog A that is encoded in the genome of human.


KLHL9_HUMAN Kelch-like protein 9 (sprot)

A kelch-like protein 9 that is encoded in the genome of human.


SYLC_HUMAN Leucine--tRNA ligase, cytoplasmic (sprot)

A leucine--tRNA ligase, cytoplasmic that is encoded in the genome of human.


ZN624_HUMAN Zinc finger protein 624 (sprot)

A zinc finger protein 624 that is encoded in the genome of human.


PDP2_HUMAN [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial (sprot)

A [pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial that is encoded in the genome of human.


C2D2A_HUMAN Coiled-coil and C2 domain-containing protein 2A (sprot)

A coiled-coil and C2 domain-containing protein 2A that is encoded in the genome of human.


TXD16_HUMAN Thioredoxin domain-containing protein 16 (sprot)

A thioredoxin domain-containing protein 16 that is encoded in the genome of human.


RCOR3_HUMAN REST corepressor 3 (sprot)

A REST corepressor 3 that is encoded in the genome of human.


MYEF2_HUMAN Myelin expression factor 2 (sprot)

A myelin expression factor 2 that is encoded in the genome of human.


KLH42_HUMAN Kelch-like protein 42 (sprot)

A kelch-like protein 42 that is encoded in the genome of human.


E2AK4_HUMAN eIF-2-alpha kinase GCN2 (sprot)

An eIF-2-alpha kinase GCN2 that is encoded in the genome of human.


positive regulation of translational initiation in response to starvation

Any process that activates or increases the frequency, rate or extent of translation initiation, as a result of deprivation of nourishment.


DISP3_HUMAN Protein dispatched homolog 3 (sprot)

A protein dispatched homolog 3 that is encoded in the genome of human.


WDR35_HUMAN WD repeat-containing protein 35 (sprot)

A WD repeat-containing protein 35 that is encoded in the genome of human.


LR2BP_HUMAN LRP2-binding protein (sprot)

An LRP2-binding protein that is encoded in the genome of human.


TBC14_HUMAN TBC1 domain family member 14 (sprot)

A TBC1 domain family member 14 that is encoded in the genome of human.


CING_HUMAN Cingulin (sprot)

A cingulin that is encoded in the genome of human.


RHG28_HUMAN Rho GTPase-activating protein 28 (sprot)

A Rho GTPase-activating protein 28 that is encoded in the genome of human.


ATS9_HUMAN A disintegrin and metalloproteinase with thrombospondin motifs 9 (sprot)

An a disintegrin and metalloproteinase with thrombospondin motifs 9 that is encoded in the genome of human.


endothelial cell-matrix adhesion

The binding of an endothelial cell to the extracellular matrix via adhesion molecules.


RBM27_HUMAN RNA-binding protein 27 (sprot)

An RNA-binding protein 27 that is encoded in the genome of human.


KANL3_HUMAN KAT8 regulatory NSL complex subunit 3 (sprot)

A KAT8 regulatory NSL complex subunit 3 that is encoded in the genome of human.


KLH13_HUMAN Kelch-like protein 13 (sprot)

A kelch-like protein 13 that is encoded in the genome of human.


NYNRI_HUMAN Protein NYNRIN (sprot)

A protein NYNRIN that is encoded in the genome of human.


HECW2_HUMAN E3 ubiquitin-protein ligase HECW2 (sprot)

An E3 ubiquitin-protein ligase HECW2 that is encoded in the genome of human.


STAR9_HUMAN StAR-related lipid transfer protein 9 (sprot)

A StAR-related lipid transfer protein 9 that is encoded in the genome of human.


FRM4A_HUMAN FERM domain-containing protein 4A (sprot)

A FERM domain-containing protein 4A that is encoded in the genome of human.


ANFY1_HUMAN Rabankyrin-5 (sprot)

A rabankyrin-5 that is encoded in the genome of human.


RERE_HUMAN Arginine-glutamic acid dipeptide repeats protein (sprot)

An arginine-glutamic acid dipeptide repeats protein that is encoded in the genome of human.


SUCB1_HUMAN Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial (sprot)

A succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial that is encoded in the genome of human.


succinate-CoA ligase (ADP-forming) activity

Catalysis of the reaction: ATP + succinate + CoA = ADP + succinyl-CoA + phosphate.


succinyl-CoA pathway

The chemical reactions that utilize succinyl-CoA in the synthesis of protoporphyrin IX.


NRX2A_HUMAN Neurexin-2 (sprot)

A neurexin-2-alpha that is encoded in the genome of human.


WRP73_HUMAN WD repeat-containing protein WRAP73 (sprot)

A WD repeat-containing protein WRAP73 that is encoded in the genome of human.


ANKY1_HUMAN Ankyrin repeat and MYND domain-containing protein 1 (sprot)

An ankyrin repeat and MYND domain-containing protein 1 that is encoded in the genome of human.


SPMA2_HUMAN Sperm microtubule associated protein 2 (sprot)

A testicular haploid expressed gene protein that is encoded in the genome of human.


GMPR2_HUMAN GMP reductase 2 (sprot)

A GMP reductase 2 that is encoded in the genome of human.


VGLU1_HUMAN Vesicular glutamate transporter 1 (sprot)

A vesicular glutamate transporter 1 that is encoded in the genome of human.


VGLU2_HUMAN Vesicular glutamate transporter 2 (sprot)

A vesicular glutamate transporter 2 that is encoded in the genome of human.


LRIT1_HUMAN Leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 1 (sprot)

A leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 1 that is encoded in the genome of human.


HOP2_HUMAN Homologous-pairing protein 2 homolog (sprot)

A homologous-pairing protein 2 that is encoded in the genome of human.


GBG13_HUMAN Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 (sprot)

A guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 that is encoded in the genome of human.


CK021_HUMAN Uncharacterized protein C11orf21 (sprot)

A protein that is a translation product of the C11orf21 gene in human.


B3GA1_HUMAN Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1 (sprot)

A galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1 that is encoded in the genome of human.


STX18_HUMAN Syntaxin-18 (sprot)

A syntaxin-18 that is encoded in the genome of human.


positive regulation of organelle assembly

Any process that activates or increases the frequency, rate or extent of organelle assembly.


DPM3_HUMAN Dolichol-phosphate mannosyltransferase subunit 3 (sprot)

A dolichol-phosphate mannosyltransferase subunit 3 that is encoded in the genome of human.


protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan

The glycosylation of a peptidyl-tryptophan residue by the transfer of alpha-mannopyranose from dolichyl-activated mannose to the indole ring.


mannosyltransferase complex

A complex that posseses mannosyltransferase activity.


IMPCT_HUMAN Protein IMPACT (sprot)

A protein IMPACT that is encoded in the genome of human.


regulation of cytoplasmic translational initiation in response to stress

Modulation of the frequency, rate or extent of cytoplasmic translational initiation as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).


DEC1_HUMAN Deleted in esophageal cancer 1 (sprot)

A deleted in esophageal cancer 1 that is encoded in the genome of human.


CI027_HUMAN Putative uncharacterized protein encoded by LINC00474 (sprot)


ZN219_HUMAN Zinc finger protein 219 (sprot)

A zinc finger protein 219 that is encoded in the genome of human.


UVRAG_HUMAN UV radiation resistance-associated gene protein (sprot)

A UV radiation resistance-associated gene protein that is encoded in the genome of human.


THA10_HUMAN THAP domain-containing protein 10 (sprot)

A THAP domain-containing protein 10 that is encoded in the genome of human.


POK18_HUMAN Endogenous retrovirus group K member 18 Pol protein (sprot)


ATX10_HUMAN Ataxin-10 (sprot)

An ataxin-10 that is encoded in the genome of human.


MBD2_HUMAN Methyl-CpG-binding domain protein 2 (sprot)

A methyl-CpG-binding domain protein 2 that is encoded in the genome of human.


NCDN_HUMAN Neurochondrin (sprot)

A neurochondrin that is encoded in the genome of human.


TFP11_HUMAN Tuftelin-interacting protein 11 (sprot)

A tuftelin-interacting protein 11 that is encoded in the genome of human.


spliceosomal complex disassembly

Disassembly of a spliceosomal complex with the ATP-dependent release of the product RNAs, one of which is composed of the joined exons. In cis splicing, the other product is the excised sequence, often a single intron, in a lariat structure.


negative regulation of DNA ligase activity

Any process that stops, prevents or reduces the frequency, rate or extent of DNA ligase activity.


HNF6_HUMAN Hepatocyte nuclear factor 6 (sprot)

A hepatocyte nuclear factor 6 that is encoded in the genome of human.


IKBL1_HUMAN NF-kappa-B inhibitor-like protein 1 (sprot)

An NF-kappa-B inhibitor-like protein 1 that is encoded in the genome of human.


EP15R_HUMAN Epidermal growth factor receptor substrate 15-like 1 (sprot)

An epidermal growth factor receptor substrate 15-like 1 that is encoded in the genome of human.


DNM3B_HUMAN DNA (cytosine-5)-methyltransferase 3B (sprot)

A DNA (cytosine-5)-methyltransferase 3B that is encoded in the genome of human.


MYO1A_HUMAN Unconventional myosin-Ia (sprot)

A myosin-Ia that is encoded in the genome of human.


GALP_HUMAN Galanin-like peptide (sprot)

A galanin-like peptide that is encoded in the genome of human.


SPRR3_HUMAN Small proline-rich protein 3 (sprot)

A small proline-rich protein 3 that is encoded in the genome of human.


HSFX1_HUMAN Heat shock transcription factor, X-linked (sprot)

A heat shock transcription factor, X-linked that is encoded in the genome of human.


XCL2_HUMAN Cytokine SCM-1 beta (sprot)

A cytokine SCM-1 beta that is encoded in the genome of human.


ORC3_HUMAN Origin recognition complex subunit 3 (sprot)

An origin recognition complex subunit 3 that is encoded in the genome of human.


RHCG_HUMAN Ammonium transporter Rh type C (sprot)

An ammonium transporter Rh type C that is encoded in the genome of human.


CLCF1_HUMAN Cardiotrophin-like cytokine factor 1 (sprot)

A cardiotrophin-like cytokine factor 1 that is encoded in the genome of human.


SAE1_HUMAN SUMO-activating enzyme subunit 1 (sprot)

A SUMO-activating enzyme subunit 1 that is encoded in the genome of human.


SUMO activating enzyme activity

Catalysis of the activation of the proteolytically processed small ubiquitin-related modifier SUMO, through the formation of an ATP-dependent high-energy thiolester bond.


SUMO activating enzyme complex

A conserved heterodimeric complex with SUMO activating enzyme activity.


NLK_HUMAN Serine/threonine-protein kinase NLK (sprot)

A serine/threonine-protein kinase NLK that is encoded in the genome of human.


serine phosphorylation of STAT protein

The process of introducing a phosphate group to a serine residue of a STAT (Signal Transducer and Activator of Transcription) protein.


MAGC2_HUMAN Melanoma-associated antigen C2 (sprot)

A melanoma-associated antigen C2 that is encoded in the genome of human.


COPG2_HUMAN Coatomer subunit gamma-2 (sprot)

A coatomer subunit gamma-2 that is encoded in the genome of human.


RBX2_HUMAN RING-box protein 2 (sprot)

A RING-box protein 2 that is encoded in the genome of human.


PI4KB_HUMAN Phosphatidylinositol 4-kinase beta (sprot)

A phosphatidylinositol 4-kinase beta that is encoded in the genome of human.


MYOTI_HUMAN Myotilin (sprot)

A myotilin that is encoded in the genome of human.


MRC2_HUMAN C-type mannose receptor 2 (sprot)

A C-type mannose receptor 2 that is encoded in the genome of human.


CRNN_HUMAN Cornulin (sprot)

A cornulin that is encoded in the genome of human.


RBPJL_HUMAN Recombining binding protein suppressor of hairless-like protein (sprot)

A recombining binding protein suppressor of hairless-like protein that is encoded in the genome of human.


I36RA_HUMAN Interleukin-36 receptor antagonist protein (sprot)

An interleukin-1 family member 5 that is encoded in the genome of human.


S53A1_HUMAN Solute carrier family 53 member 1 (sprot)

A xenotropic and polytropic retrovirus receptor 1 that is encoded in the genome of human.


COMD3_HUMAN COMM domain-containing protein 3 (sprot)

A COMM domain-containing protein 3 that is encoded in the genome of human.


STML1_HUMAN Stomatin-like protein 1 (sprot)

A stomatin-like protein 1 that is encoded in the genome of human.


GBG12_HUMAN Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 (sprot)

A guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 that is encoded in the genome of human.


HDC_HUMAN Headcase protein homolog (sprot)

A headcase protein that is encoded in the genome of human.


ABCD2_HUMAN ATP-binding cassette sub-family D member 2 (sprot)

An ATP-binding cassette sub-family D member 2 that is encoded in the genome of human.


PRGC1_HUMAN Peroxisome proliferator-activated receptor gamma coactivator 1-alpha (sprot)

A peroxisome proliferator-activated receptor gamma coactivator 1-alpha that is encoded in the genome of human.


HCST_HUMAN Hematopoietic cell signal transducer (sprot)

A hematopoietic cell signal transducer that is encoded in the genome of human.


RBL2A_HUMAN Rab-like protein 2A (sprot)

A Rab-like protein 2A that is encoded in the genome of human.


MTRR_HUMAN Methionine synthase reductase (sprot)

A methionine synthase reductase that is encoded in the genome of human.


[methionine synthase] reductase activity

Catalysis of the reaction: [methionine synthase]-cob(II)alamin + NADPH + H+ + S-adenosyl methionine = [methionine synthase]-methylcob(I)alamin + S-adenosylhomocysteine + NADP+.


S-adenosylmethionine cycle

A cyclic series of interconversions involving S-adenosylmethionine, S-adenosyl-L-homocysteine, L-cysteine, and L-methionine. Couples utilization of the methyl group of SAM with recycling of the homocysteinyl group and regeneration of methionine.


negative regulation of cystathionine beta-synthase activity

Any process that stops, prevents or reduces the frequency, rate or extent of cystathionine beta-synthase activity.


UXT_HUMAN Protein UXT (sprot)

A protein UXT that is encoded in the genome of human.


ARP21_HUMAN cAMP-regulated phosphoprotein 21 (sprot)

A cAMP-regulated phosphoprotein 21 that is encoded in the genome of human.


ASH2L_HUMAN Set1/Ash2 histone methyltransferase complex subunit ASH2 (sprot)

A Set1/Ash2 histone methyltransferase complex subunit ASH2 that is encoded in the genome of human.


CPNE7_HUMAN Copine-7 (sprot)

A copine-7 that is encoded in the genome of human.


P2RX2_HUMAN P2X purinoceptor 2 (sprot)

A P2X purinoceptor 2 that is encoded in the genome of human.


detection of hypoxic conditions in blood by carotid body chemoreceptor signaling

The process in which information about a lack of oxygen are received and are converted to a molecular signal by chemoreceptors in the carotid bodies.


PEMT_HUMAN Phosphatidylethanolamine N-methyltransferase (sprot)

A phosphatidylethanolamine N-methyltransferase that is encoded in the genome of human.


Catalysis of the reaction: S-adenosyl-L-methionine + phosphatidyl-N-methylethanolamine = S-adenosyl-L-homocysteine + phosphatidyl-N-dimethylethanolamine.


Catalysis of the reaction: S-adenosyl-L-methionine + phosphatidylethanolamine = S-adenosyl-L-homocysteine + H+ + phosphatidyl-N-methylethanolamine.


Catalysis of the reaction: S-adenosyl-L-methionine + phosphatidyl-N-dimethylethanolamine = S-adenosyl-L-homocysteine + phosphatidylcholine.


OPT_HUMAN Opticin (sprot)

An opticin that is encoded in the genome of human.


DHCR7_HUMAN 7-dehydrocholesterol reductase (sprot)

A 7-dehydrocholesterol reductase that is encoded in the genome of human.


7-dehydrocholesterol reductase activity

Catalysis of the reaction: cholesterol + NADP+ = cholesta-5,7-dien-3-beta-ol + NADPH + H+.


MGT4C_HUMAN Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C (sprot)

An alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C that is encoded in the genome of human.


Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + (N-acetyl-beta-D-glucosaminyl-1,2)-alpha-D-mannosyl-1,3-(beta-N-acetyl-D-glucosaminyl-1,2-alpha-D-mannosyl-1,6)-beta-D-mannosyl-R = UDP + N-acetyl-beta-D-glucosaminyl-1,4-(N-acetyl-D-glucosaminyl-1,2)-alpha-D-mannosyl-1,3-(beta-N-acetyl-D-glucosaminyl-1,2-alpha-D-mannosyl-1,6)-beta-D-mannosyl-R.


CCG4_HUMAN Voltage-dependent calcium channel gamma-4 subunit (sprot)

A voltage-dependent calcium channel gamma-4 subunit that is encoded in the genome of human.


TRPC4_HUMAN Short transient receptor potential channel 4 (sprot)

A short transient receptor potential cation channel TRPC4 that is encoded in the genome of human.


TR10D_HUMAN Tumor necrosis factor receptor superfamily member 10D (sprot)

A tumor necrosis factor receptor superfamily member 10D that is encoded in the genome of human.


HDAC6_HUMAN Histone deacetylase 6 (sprot)

A histone deacetylase 6 that is encoded in the genome of human.


negative regulation of hydrogen peroxide metabolic process

Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving hydrogen peroxide.


cellular response to topologically incorrect protein

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a protein that is not folded in its correct three-dimensional structure.


polyubiquitinated misfolded protein transport

The directed movement of misfolded polyubiquitinated proteins in a cell, including the movement of proteins between specific compartments or structures within a cell.


SPAST_HUMAN Spastin (sprot)

A spastin that is encoded in the genome of human.


mitotic spindle disassembly

The controlled breakdown of the spindle during a mitotic cell cycle.


DKK3_HUMAN Dickkopf-related protein 3 (sprot)

A dickkopf-related protein 3 that is encoded in the genome of human.


negative regulation of anti-Mullerian hormone signaling pathway

Any process that stops, prevents or reduces the frequency, rate or extent of anti-Mullerian hormone signaling pathway.


HEY2_HUMAN Hairy/enhancer-of-split related with YRPW motif protein 2 (sprot)

A hairy/enhancer-of-split related with YRPW motif protein 2 that is encoded in the genome of human.


umbilical cord morphogenesis

The process in which the anatomical structures of the umbilical cord are generated and organized. The umbilical cord is an organ or embryonic origin consisting of the 2 umbilical arteries and the one umbilical vein. The umbilical cord connects the cardiovascular system of the fetus to the mother via the placenta.


negative regulation of cardiac vascular smooth muscle cell differentiation

Any process that stops, prevents or reduces the frequency, rate or extent of cardiac vascular smooth muscle cell differentiation.


TRMB_HUMAN tRNA (guanine-N(7)-)-methyltransferase (sprot)

A tRNA (guanine-N(7)-)-methyltransferase that is encoded in the genome of human.


Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing N7-methylguanine.


RNA (guanine-N7)-methylation

The addition of a methyl group to the N7 atom in the base portion of a guanine nucleotide residue in an RNA molecule.


KAAG1_HUMAN Kidney-associated antigen 1 (sprot)

A kidney-associated antigen 1 that is encoded in the genome of human.


GULP1_HUMAN PTB domain-containing engulfment adapter protein 1 (sprot)

A PTB domain-containing engulfment adapter protein 1 that is encoded in the genome of human.


VPS29_HUMAN Vacuolar protein sorting-associated protein 29 (sprot)

A vacuolar protein sorting-associated protein 29 that is encoded in the genome of human.


EIF3K_HUMAN Eukaryotic translation initiation factor 3 subunit K (sprot)

A eukaryotic translation initiation factor 3 subunit K that is encoded in the genome of human.


EXTL2_HUMAN Exostosin-like 2 (sprot)

An exostosin-like 2 that is encoded in the genome of human.


Catalysis of the transfer of an N-acetylgalactosaminyl residue from UDP-N-acetyl-galactosamine to an acceptor molecule, forming an alpha-1,4 linkage.


GRHPR_HUMAN Glyoxylate reductase/hydroxypyruvate reductase (sprot)

A glyoxylate reductase/hydroxypyruvate reductase that is encoded in the genome of human.


glycerate dehydrogenase activity

Catalysis of the reaction: (R)-glycerate + NAD+ = hydroxypyruvate + NADH + H+.


hydroxypyruvate reductase activity

Catalysis of the reaction: D-glycerate + NADP+ = hydroxypyruvate + NADPH + H+.


glyoxylate reductase (NADP+) activity

Catalysis of the reaction: glycolate + NADP+ = glyoxylate + NADPH + H+.


A beta-ureidopropionase that is encoded in the genome of human.


beta-ureidopropionase activity

Catalysis of the reaction: N-carbamoyl-beta-alanine + H2O = beta-alanine + CO2 + NH3.


beta-alanine biosynthetic process via 3-ureidopropionate

The chemical reactions and pathways resulting in the formation of beta-alanine via the intermediate 3-ureidopropionate.


pyrimidine nucleoside catabolic process

The chemical reactions and pathways resulting in the breakdown of one of a family of organic molecules consisting of a pyrimidine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside).


CATZ_HUMAN Cathepsin Z (sprot)

A cathepsin Z that is encoded in the genome of human.


LHX3_HUMAN LIM/homeobox protein Lhx3 (sprot)

A LIM/homeobox protein Lhx3 that is encoded in the genome of human.


CKLF_HUMAN Chemokine-like factor (sprot)

A chemokine-like factor that is encoded in the genome of human.


KS6B2_HUMAN Ribosomal protein S6 kinase beta-2 (sprot)

A ribosomal protein S6 kinase beta-2 that is encoded in the genome of human.


DNJB9_HUMAN DnaJ homolog subfamily B member 9 (sprot)

A DnaJ homolog subfamily B member 9 that is encoded in the genome of human.


DJB11_HUMAN DnaJ homolog subfamily B member 11 (sprot)

A DnaJ homolog subfamily B member 11 that is encoded in the genome of human.


GABR1_HUMAN Gamma-aminobutyric acid type B receptor subunit 1 (sprot)

A gamma-aminobutyric acid type B receptor subunit 1 that is encoded in the genome of human.


RNF14_HUMAN E3 ubiquitin-protein ligase RNF14 (sprot)

An E3 ubiquitin-protein ligase RNF14 that is encoded in the genome of human.


SUCO_HUMAN SUN domain-containing ossification factor (sprot)

A SUN domain-containing ossification factor that is encoded in the genome of human.


SAE2_HUMAN SUMO-activating enzyme subunit 2 (sprot)

A SUMO-activating enzyme subunit 2 that is encoded in the genome of human.


DKK4_HUMAN Dickkopf-related protein 4 (sprot)

A dickkopf-related protein 4 that is encoded in the genome of human.


negative regulation of hair follicle placode formation

Any process that decreases the rate, frequency, or extent of hair follicle placode formation, the developmental process in which a hair placode forms. An hair follicle placode is a thickening of the ectoderm that will give rise to the hair follicle bud.


POLK_HUMAN DNA polymerase kappa (sprot)

A DNA polymerase kappa that is encoded in the genome of human.


CTNL1_HUMAN Alpha-catulin (sprot)

An alpha-catulin that is encoded in the genome of human.


DKK2_HUMAN Dickkopf-related protein 2 (sprot)

A dickkopf-related protein 2 that is encoded in the genome of human.


GHRL_HUMAN Appetite-regulating hormone (sprot)

An appetite-regulating hormone that is encoded in the genome of human.


ghrelin receptor binding

Binding to a ghrelin receptor.


negative regulation of locomotion

Any process that stops, prevents, or reduces the frequency, rate or extent of locomotion of a cell or organism.


cortisol secretion

The regulated release of cortisol, a steroid hormone that in humans is the major circulating hormone of the cortex, or outer layer, of the adrenal gland.


positive regulation of gastric mucosal blood circulation

Any process that activates or increases the frequency, rate or extent of gastric mucosal blood circulation.


FA8A1_HUMAN Protein FAM8A1 (sprot)

A protein FAM8A1 that is encoded in the genome of human.


DBF4A_HUMAN Protein DBF4 homolog A (sprot)

A protein DBF4 homolog A that is encoded in the genome of human.


MO4L1_HUMAN Mortality factor 4-like protein 1 (sprot)

A mortality factor 4-like protein 1 that is encoded in the genome of human.


NXF1_HUMAN Nuclear RNA export factor 1 (sprot)

A nuclear RNA export factor 1 that is encoded in the genome of human.


SE1L1_HUMAN Protein sel-1 homolog 1 (sprot)

A protein sel-1 homolog 1 that is encoded in the genome of human.


WNT16_HUMAN Protein Wnt-16 (sprot)

A protein Wnt-16 that is encoded in the genome of human.


B4GT7_HUMAN Beta-1,4-galactosyltransferase 7 (sprot)

A beta-1,4-galactosyltransferase 7 that is encoded in the genome of human.


Catalysis of the reaction: UDP-galactose + O-beta-D-xylosylprotein = UDP + 4-beta-D-galactosyl-O-beta-D-xylosylprotein.


PEF1_HUMAN Peflin (sprot)

A peflin that is encoded in the genome of human.


BIN2_HUMAN Bridging integrator 2 (sprot)

A bridging integrator 2 that is encoded in the genome of human.


ZMYM2_HUMAN Zinc finger MYM-type protein 2 (sprot)

A zinc finger MYM-type protein 2 that is encoded in the genome of human.


CSN7A_HUMAN COP9 signalosome complex subunit 7a (sprot)

A COP9 signalosome complex subunit 7a that is encoded in the genome of human.


HESX1_HUMAN Homeobox expressed in ES cells 1 (sprot)

A homeobox expressed in ES cells 1 that is encoded in the genome of human.


CATF_HUMAN Cathepsin F (sprot)

A cathepsin F that is encoded in the genome of human.


DUX4_HUMAN Double homeobox protein 4 (sprot)

A double homeobox protein 4 that is encoded in the genome of human.


DIC_HUMAN Mitochondrial dicarboxylate carrier (sprot)

A mitochondrial dicarboxylate carrier that is encoded in the genome of human.


FBLN5_HUMAN Fibulin-5 (sprot)

A fibulin-5 that is encoded in the genome of human.


KLK11_HUMAN Kallikrein-11 (sprot)

A kallikrein-11 that is encoded in the genome of human.


B4GT6_HUMAN Beta-1,4-galactosyltransferase 6 (sprot)

A beta-1,4-galactosyltransferase 6 that is encoded in the genome of human.


SL9A2_HUMAN Sodium/hydrogen exchanger 2 (sprot)

A sodium/hydrogen exchanger 2 that is encoded in the genome of human.


LPAR3_HUMAN Lysophosphatidic acid receptor 3 (sprot)

A lysophosphatidic acid receptor 3 that is encoded in the genome of human.


CLN8_HUMAN Protein CLN8 (sprot)

A protein CLN8 that is encoded in the genome of human.


HSPB7_HUMAN Heat shock protein beta-7 (sprot)

A heat shock protein beta-7 that is encoded in the genome of human.


APEX2_HUMAN DNA-(apurinic or apyrimidinic site) endonuclease 2 (sprot)

A DNA-(apurinic or apyrimidinic site) endonuclease 2 that is encoded in the genome of human.


REV1_HUMAN DNA repair protein REV1 (sprot)

A DNA repair protein REV1 that is encoded in the genome of human.


deoxycytidyl transferase activity

Catalysis of the insertion of a dCMP residue opposite a template abasic site in DNA.


ZNF70_HUMAN Zinc finger protein 70 (sprot)

A zinc finger protein 70 that is encoded in the genome of human.


ZNF69_HUMAN Zinc finger protein 69 (sprot)

A zinc finger protein 69 that is encoded in the genome of human.


NKX12_HUMAN NK1 transcription factor-related protein 2 (sprot)

An NK1 transcription factor-related protein 2 that is encoded in the genome of human.


PPR1B_HUMAN Protein phosphatase 1 regulatory subunit 1B (sprot)

A protein phosphatase 1 regulatory subunit 1B that is encoded in the genome of human.


AASS_HUMAN Alpha-aminoadipic semialdehyde synthase, mitochondrial (sprot)

An alpha-aminoadipic semialdehyde synthase, mitochondrial that is encoded in the genome of human.


saccharopine dehydrogenase (NAD+, L-lysine-forming) activity

Catalysis of the reaction: L-saccharopine + H2O + NAD+ = 2-oxoglutarate + L-lysine + H+ + NADH.


saccharopine dehydrogenase (NADP+, L-lysine-forming) activity

Catalysis of the reaction: L-saccharopine + H2O + NADP+ = 2-oxoglutarate + L-lysine + H+ + NADPH.


saccharopine dehydrogenase (NAD+, L-glutamate-forming) activity

Catalysis of the reaction: L-saccharopine + H2O + NAD+ = L-glutamate + allysine + H+ + NADH.


CLIP2_HUMAN CAP-Gly domain-containing linker protein 2 (sprot)

A CAP-Gly domain-containing linker protein 2 that is encoded in the genome of human.


ZN212_HUMAN Zinc finger protein 212 (sprot)

A zinc finger protein 212 that is encoded in the genome of human.


ZN282_HUMAN Zinc finger protein 282 (sprot)

A zinc finger protein 282 that is encoded in the genome of human.


QCR9_HUMAN Cytochrome b-c1 complex subunit 9 (sprot)

A cytochrome b-c1 complex subunit 9 that is encoded in the genome of human.


ZMAT5_HUMAN Zinc finger matrin-type protein 5 (sprot)

A zinc finger matrin-type protein 5 that is encoded in the genome of human.


S14L4_HUMAN SEC14-like protein 4 (sprot)

A SEC14-like protein 4 that is encoded in the genome of human.


S14L3_HUMAN SEC14-like protein 3 (sprot)

A SEC14-like protein 3 that is encoded in the genome of human.


MTFP1_HUMAN Mitochondrial fission process protein 1 (sprot)

A mitochondrial 18 kDa protein that is encoded in the genome of human.


ZO2_HUMAN Tight junction protein ZO-2 (sprot)

A tight junction protein ZO-2 that is encoded in the genome of human.


DNJB4_HUMAN DnaJ homolog subfamily B member 4 (sprot)

A DnaJ homolog subfamily B member 4 that is encoded in the genome of human.


TRI10_HUMAN Tripartite motif-containing protein 10 (sprot)

A tripartite motif-containing protein 10 that is encoded in the genome of human.


MALT1_HUMAN Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (sprot)

A mucosa-associated lymphoid tissue lymphoma translocation protein 1 that is encoded in the genome of human.


ST17A_HUMAN Serine/threonine-protein kinase 17A (sprot)

A serine/threonine-protein kinase 17A that is encoded in the genome of human.


CFDP1_HUMAN Craniofacial development protein 1 (sprot)

A craniofacial development protein 1 that is encoded in the genome of human.


KLOT_HUMAN Klotho (sprot)

A klotho that is encoded in the genome of human.


ZN629_HUMAN Zinc finger protein 629 (sprot)

A zinc finger protein 629 that is encoded in the genome of human.


DAXX_HUMAN Death domain-associated protein 6 (sprot)

A death domain-associated protein 6 that is encoded in the genome of human.


TRM7_HUMAN tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase (sprot)

A ribosomal RNA methyltransferase 1 that is encoded in the genome of human.


tRNA (guanine) methyltransferase activity

Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing methylguanine.


tRNA (cytidine 32-2'-O)-methyltransferase activity

Catalysis of the reaction: S-adenosyl-L-methionine + cytosine32 in tRNA= S-adenosyl-L-homocysteine + 2'-O-methylcytidine32 in tRNA.


tRNA (guanosine 34-2'-O)-methyltransferase activity

Catalysis of the reaction: S-adenosyl-L-methionine + guanosine 34 in tRNA= S-adenosyl-L-homocysteine + 2'-O-methylguanosine 34 in tRNA.


VTI1B_HUMAN Vesicle transport through interaction with t-SNAREs homolog 1B (sprot)

A vesicle transport through interaction with t-SNAREs homolog 1B that is encoded in the genome of human.


GGE2D_HUMAN G antigen 2D (sprot)

A G antigen 2D that is encoded in the genome of human.


MARCO_HUMAN Macrophage receptor MARCO (sprot)

A macrophage receptor MARCO that is encoded in the genome of human.


STK39_HUMAN STE20/SPS1-related proline-alanine-rich protein kinase (sprot)

A STE20/SPS1-related proline-alanine-rich protein kinase that is encoded in the genome of human.


ADDG_HUMAN Gamma-adducin (sprot)

A gamma-adducin that is encoded in the genome of human.


CCG5_HUMAN Voltage-dependent calcium channel gamma-5 subunit (sprot)

A voltage-dependent calcium channel gamma-5 subunit that is encoded in the genome of human.


PKHB1_HUMAN Pleckstrin homology domain-containing family B member 1 (sprot)

A pleckstrin homology domain-containing family B member 1 that is encoded in the genome of human.


HYPDH_HUMAN Hydroxyproline dehydrogenase (sprot)

A hydroxyproline dehydrogenase that is encoded in the genome of human.


oxidoreductase activity, acting on the CH-NH group of donors

Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.


EPHA6_HUMAN Ephrin type-A receptor 6 (sprot)

An ephrin type-A receptor 6 that is encoded in the genome of human.


DNJ5B_HUMAN DnaJ homolog subfamily C member 5B (sprot)

A DnaJ homolog subfamily C member 5B that is encoded in the genome of human.


FXL17_HUMAN F-box/LRR-repeat protein 17 (sprot)

An F-box/LRR-repeat protein 17 that is encoded in the genome of human.


YM012_HUMAN Uncharacterized protein DKFZp434B061 (sprot)


ZBT47_HUMAN Zinc finger and BTB domain-containing protein 47 (sprot)

A zinc finger and BTB domain-containing protein 47 that is encoded in the genome of human.


LRWD1_HUMAN Leucine-rich repeat and WD repeat-containing protein 1 (sprot)

A leucine-rich repeat and WD repeat-containing protein 1 that is encoded in the genome of human.


RIM3A_HUMAN RIMS-binding protein 3A (sprot)

A RIMS-binding protein 3A that is encoded in the genome of human.


CCD39_HUMAN Coiled-coil domain-containing protein 39 (sprot)

A coiled-coil domain-containing protein 39 that is encoded in the genome of human.


CNOT8_HUMAN CCR4-NOT transcription complex subunit 8 (sprot)

A CCR4-NOT transcription complex subunit 8 that is encoded in the genome of human.


CS025_HUMAN UPF0449 protein C19orf25 (sprot)

A UPF0449 protein C19orf25 that is encoded in the genome of human.


DYH17_HUMAN Dynein axonemal heavy chain 17 (sprot)

A dynein axonemal heavy chain 17 that is encoded in the genome of human.


NPS3A_HUMAN Protein NipSnap homolog 3A (sprot)

A protein NipSnap homolog 3A that is encoded in the genome of human.


GAK1A_HUMAN Golgi-associated kinase 1A (sprot)

A Golgi-associated kinase 1A that is encoded in the genome of human.


CGBP1_HUMAN CGG triplet repeat-binding protein 1 (sprot)

A CGG triplet repeat-binding protein 1 that is encoded in the genome of human.


IF172_HUMAN Intraflagellar transport protein 172 homolog (sprot)

An intraflagellar transport protein 172 that is encoded in the genome of human.


hindgut development

The process whose specific outcome is the progression of the hindgut over time, from its formation to the mature structure. The hindgut is part of the alimentary canal that lies posterior to the midgut.


GIMA2_HUMAN GTPase IMAP family member 2 (sprot)

A GTPase IMAP family member 2 that is encoded in the genome of human.


PISD_HUMAN Phosphatidylserine decarboxylase proenzyme, mitochondrial (sprot)

A phosphatidylserine decarboxylase proenzyme that is encoded in the genome of human.


ABCF2_HUMAN ATP-binding cassette sub-family F member 2 (sprot)

An ATP-binding cassette sub-family F member 2 that is encoded in the genome of human.


MIOX_HUMAN Inositol oxygenase (sprot)

An inositol oxygenase that is encoded in the genome of human.


inositol oxygenase activity

Catalysis of the reaction: myo-inositol + O2 = D-glucuronate + H2O + H+.


inositol catabolic process

The chemical reactions and pathways resulting in the breakdown of inositol, 1,2,3,4,5,6-cyclohexanehexol, a growth factor for animals and microorganisms.


RGS17_HUMAN Regulator of G-protein signaling 17 (sprot)

A regulator of G-protein signaling 17 that is encoded in the genome of human.


RF1ML_HUMAN Peptide chain release factor 1-like, mitochondrial (sprot)

A peptide chain release factor 1-like, mitochondrial that is encoded in the genome of human.


O14J1_HUMAN Olfactory receptor 14J1 (sprot)

An olfactory receptor 14J1 that is encoded in the genome of human.


OR5V1_HUMAN Olfactory receptor 5V1 (sprot)

An olfactory receptor 5V1 that is encoded in the genome of human.


O12D3_HUMAN Olfactory receptor 12D3 (sprot)

An olfactory receptor 12D3 that is encoded in the genome of human.


S23A2_HUMAN Solute carrier family 23 member 2 (sprot)

A solute carrier family 23 member 2 that is encoded in the genome of human.


Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: L-ascorbate(out) + Na+(out) = L-ascorbate(in) + Na+(in).


L-ascorbic acid transmembrane transporter activity

Enables the transfer of L-ascorbate from one side of a membrane to the other. L-ascorbate, (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate, is vitamin C and has co-factor and anti-oxidant activities in many species.


L-ascorbic acid transmembrane transport

The process in which L-ascorbic acid is transported across a lipid bilayer, from one side of a membrane to the other. L-ascorbate, (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate, is vitamin C and has co-factor and anti-oxidant activities in many species.


ZRAN1_HUMAN Ubiquitin thioesterase ZRANB1 (sprot)

A ubiquitin thioesterase ZRANB1 that is encoded in the genome of human.


KCNN3_HUMAN Small conductance calcium-activated potassium channel protein 3 (sprot)

A small conductance calcium-activated potassium channel protein 3 that is encoded in the genome of human.


TES_HUMAN Testin (sprot)

A testin that is encoded in the genome of human.


AAKG3_HUMAN 5'-AMP-activated protein kinase subunit gamma-3 (sprot)

A 5'-AMP-activated protein kinase subunit gamma-3 that is encoded in the genome of human.


AAKG2_HUMAN 5'-AMP-activated protein kinase subunit gamma-2 (sprot)

A 5'-AMP-activated protein kinase subunit gamma-2 that is encoded in the genome of human.


GCP4_HUMAN Gamma-tubulin complex component 4 (sprot)

A gamma-tubulin complex component 4 that is encoded in the genome of human.


STAP2_HUMAN Signal-transducing adaptor protein 2 (sprot)

A signal-transducing adaptor protein 2 that is encoded in the genome of human.


SRGEF_HUMAN Secretion-regulating guanine nucleotide exchange factor (sprot)

A secretion-regulating guanine nucleotide exchange factor that is encoded in the genome of human.


KDM5B_HUMAN Lysine-specific demethylase 5B (sprot)

A lysine-specific demethylase 5B that is encoded in the genome of human.


regulation of estradiol secretion

Any process that modulates the frequency, rate or extent of estradiol secretion.


CRCT1_HUMAN Cysteine-rich C-terminal protein 1 (sprot)

A cysteine-rich C-terminal protein 1 that is encoded in the genome of human.


ACHA9_HUMAN Neuronal acetylcholine receptor subunit alpha-9 (sprot)

A neuronal acetylcholine receptor subunit alpha-9 that is encoded in the genome of human.


DMBT1_HUMAN Deleted in malignant brain tumors 1 protein (sprot)

A deleted in malignant brain tumors 1 protein that is encoded in the genome of human.


zymogen binding

Binding to a zymogen, an enzymatically inactive precursor of an enzyme that is often convertible to an active enzyme by proteolysis.


FETUB_HUMAN Fetuin-B (sprot)

A fetuin-B that is encoded in the genome of human.


SYWM_HUMAN Tryptophan--tRNA ligase, mitochondrial (sprot)

A tryptophan--tRNA ligase, mitochondrial that is encoded in the genome of human.


CLM8_HUMAN CMRF35-like molecule 8 (sprot)

A CMRF35-like molecule 8 that is encoded in the genome of human.


negative regulation of NK T cell activation

Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer T cell activation.


negative regulation of phagocytosis, engulfment

Any process that stops, prevents, or reduces the frequency, rate or extent of the internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis.


negative regulation of eosinophil activation

Any process that stops, prevents or reduces the frequency, rate or extent of eosinophil activation.


negative regulation of activation of Janus kinase activity

Any process that stops, prevents or reduces the frequency, rate or extent of activation of JAK (Janus Activated Kinase) kinase activity.


negative regulation of eosinophil migration

Any process that stops, prevents or reduces the frequency, rate or extent of eosinophil migration.


PARP2_HUMAN Poly [ADP-ribose] polymerase 2 (sprot)

A poly [ADP-ribose] polymerase 2 that is encoded in the genome of human.


LIMD1_HUMAN LIM domain-containing protein 1 (sprot)

A LIM domain-containing protein 1 that is encoded in the genome of human.


DPOLL_HUMAN DNA polymerase lambda (sprot)

A DNA polymerase lambda that is encoded in the genome of human.


SEC63_HUMAN Translocation protein SEC63 homolog (sprot)

A translocation protein SEC63 that is encoded in the genome of human.


FLOWR_HUMAN Calcium channel flower homolog (sprot)

A calcium channel flower homolog that is encoded in the genome of human.


GTR6_HUMAN Solute carrier family 2, facilitated glucose transporter member 6 (sprot)

A solute carrier family 2, facilitated glucose transporter member 6 that is encoded in the genome of human.


Z3H7B_HUMAN Zinc finger CCCH domain-containing protein 7B (sprot)

A zinc finger CCCH domain-containing protein 7B that is encoded in the genome of human.


SUSD2_HUMAN Sushi domain-containing protein 2 (sprot)

A sushi domain-containing protein 2 that is encoded in the genome of human.


TCF20_HUMAN Transcription factor 20 (sprot)

A transcription factor 20 that is encoded in the genome of human.


HMGX4_HUMAN HMG domain-containing protein 4 (sprot)

An HMG domain-containing protein 4 that is encoded in the genome of human.


NDRG3_HUMAN Protein NDRG3 (sprot)

A protein NDRG3 that is encoded in the genome of human.


NOL12_HUMAN Nucleolar protein 12 (sprot)

A nucleolar protein 12 that is encoded in the genome of human.


SEPT3_HUMAN Neuronal-specific septin-3 (sprot)

A neuronal-specific septin-3 that is encoded in the genome of human.


ABC3B_HUMAN DNA dC->dU-editing enzyme APOBEC-3B (sprot)

A DNA dC->dU-editing enzyme APOBEC-3B that is encoded in the genome of human.


SRR1L_HUMAN SRR1-like protein (sprot)

An SRR1-like protein that is encoded in the genome of human.


regulation of heme biosynthetic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of heme.


ARMX3_HUMAN Armadillo repeat-containing X-linked protein 3 (sprot)

An armadillo repeat-containing X-linked protein 3 that is encoded in the genome of human.


SWP70_HUMAN Switch-associated protein 70 (sprot)

A switch-associated protein 70 that is encoded in the genome of human.


COE1_HUMAN Transcription factor COE1 (sprot)

A transcription factor COE1 that is encoded in the genome of human.


KLHL3_HUMAN Kelch-like protein 3 (sprot)

A kelch-like protein 3 that is encoded in the genome of human.


FBX40_HUMAN F-box only protein 40 (sprot)

An F-box only protein 40 that is encoded in the genome of human.


MLX_HUMAN Max-like protein X (sprot)

A Max-like protein X that is encoded in the genome of human.


SUN2_HUMAN SUN domain-containing protein 2 (sprot)

A SUN domain-containing protein 2 that is encoded in the genome of human.


S18L2_HUMAN SS18-like protein 2 (sprot)

An SS18-like protein 2 that is encoded in the genome of human.


RLP24_HUMAN Probable ribosome biogenesis protein RLP24 (sprot)

A probable ribosome biogenesis protein RLP24 that is encoded in the genome of human.


LTOR3_HUMAN Ragulator complex protein LAMTOR3 (sprot)

A mitogen-activated protein kinase scaffold protein 1 that is encoded in the genome of human.


IL36A_HUMAN Interleukin-36 alpha (sprot)

An interleukin-36 alpha that is encoded in the genome of human.


NDOR1_HUMAN NADPH-dependent diflavin oxidoreductase 1 (sprot)

An NADPH-dependent diflavin oxidoreductase 1 that is encoded in the genome of human.


oxidoreductase activity, acting on iron-sulfur proteins as donors, NAD or NADP as acceptor

Catalysis of an oxidation-reduction (redox) reaction in which an iron-sulfur protein acts as a hydrogen or electron donor and reduces NAD or NADP.


LIMA1_HUMAN LIM domain and actin-binding protein 1 (sprot)

A LIM domain and actin-binding protein 1 that is encoded in the genome of human.


AFF4_HUMAN AF4/FMR2 family member 4 (sprot)

An AF4/FMR2 family member 4 that is encoded in the genome of human.


SRP68_HUMAN Signal recognition particle subunit SRP68 (sprot)

A signal recognition particle subunit SRP68 that is encoded in the genome of human.


MLH3_HUMAN DNA mismatch repair protein Mlh3 (sprot)

A DNA mismatch repair protein Mlh3 that is encoded in the genome of human.


ASIC3_HUMAN Acid-sensing ion channel 3 (sprot)

An acid-sensing ion channel 3 that is encoded in the genome of human.


enterobactin transmembrane transporter activity

Enables the directed movement of the siderochrome enterochelin, a cyclic trimer of 2, 3 dihydroxybenzoylserine from one side of a membrane to the other.


enterobactin transport

The directed movement of the siderochrome enterobactin, a cyclic trimer of 2, 3 dihydroxybenzoylserine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


CNTP2_HUMAN Contactin-associated protein-like 2 (sprot)

A contactin-associated protein-like 2 that is encoded in the genome of human.


MKRN1_HUMAN E3 ubiquitin-protein ligase makorin-1 (sprot)

A makorin-1 that is encoded in the genome of human.


NPCL1_HUMAN NPC1-like intracellular cholesterol transporter 1 (sprot)

An NPC1-like intracellular cholesterol transporter 1 that is encoded in the genome of human.


cellular response to sterol depletion

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating deprivation of sterols. Sterols are a group of steroids characterized by the presence of one or more hydroxyl groups and a hydrocarbon side-chain in the molecule.


IL19_HUMAN Interleukin-19 (sprot)

An interleukin-19 that is encoded in the genome of human.


CHRD1_HUMAN Cysteine and histidine-rich domain-containing protein 1 (sprot)

A cysteine and histidine-rich domain-containing protein 1 that is encoded in the genome of human.


TBK1_HUMAN Serine/threonine-protein kinase TBK1 (sprot)

A serine/threonine-protein kinase TBK1 that is encoded in the genome of human.


CIDEB_HUMAN Lipid transferase CIDEB (sprot)

A cell death activator CIDE-B that is encoded in the genome of human.


SEPT9_HUMAN Septin-9 (sprot)

A septin-9 that is encoded in the genome of human.


UBQL2_HUMAN Ubiquilin-2 (sprot)

A ubiquilin-2 that is encoded in the genome of human.


NAT8_HUMAN N-acetyltransferase 8 (sprot)

An N-acetyltransferase 8 that is encoded in the genome of human.


Catalysis of the reaction: S-substituted L-cysteine + acetyl-CoA = S-substituted N-acetyl-L-cysteine + CoA + H+.


peptidyl-lysine N6-acetylation

The acetylation of the peptidyl-lysine of proteins to form the derivative peptidyl-N6-acetyl-L-lysine.


STEA1_HUMAN Metalloreductase STEAP1 (sprot)

A metalloreductase STEAP1 that is encoded in the genome of human.


TKNK_HUMAN Tachykinin-3 (sprot)

A tachykinin-3 that is encoded in the genome of human.


EGFL7_HUMAN Epidermal growth factor-like protein 7 (sprot)

An epidermal growth factor-like protein 7 that is encoded in the genome of human.


NAT8B_HUMAN Putative N-acetyltransferase 8B (sprot)

A putative N-acetyltransferase 8B that is encoded in the genome of human.


I20RA_HUMAN Interleukin-20 receptor subunit alpha (sprot)

An interleukin-20 receptor subunit alpha that is encoded in the genome of human.


IL17B_HUMAN Interleukin-17B (sprot)

An interleukin-17B that is encoded in the genome of human.


TRPS1_HUMAN Zinc finger transcription factor Trps1 (sprot)

A zinc finger transcription factor Trps1 that is encoded in the genome of human.


DCDC2_HUMAN Doublecortin domain-containing protein 2 (sprot)

A doublecortin domain-containing protein 2 that is encoded in the genome of human.


PCS1N_HUMAN ProSAAS (sprot)

A ProSAAS that is encoded in the genome of human.


PCYOX_HUMAN Prenylcysteine oxidase 1 (sprot)

A prenylcysteine oxidase 1 that is encoded in the genome of human.


prenylcysteine oxidase activity

Catalysis of the reaction: S-prenyl-L-cysteine + O2 + H2O = a prenal + L-cysteine + H2O2.


farnesylcysteine lyase activity

Catalysis of the reaction: S-[(2E,6E)-farnesyl]-L-cysteine + O2 + H2O <=> (2-trans,6-trans)-farnesal + L-cysteine + hydrogen peroxide.


IP6K2_HUMAN Inositol hexakisphosphate kinase 2 (sprot)

An inositol hexakisphosphate kinase 2 that is encoded in the genome of human.


cellular response to flavonoid

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a flavonoid stimulus.


LAT2_HUMAN Large neutral amino acids transporter small subunit 2 (sprot)

A large neutral amino acids transporter small subunit 2 that is encoded in the genome of human.


DDX20_HUMAN Probable ATP-dependent RNA helicase DDX20 (sprot)

A probable ATP-dependent RNA helicase DDX20 that is encoded in the genome of human.


S23A1_HUMAN Solute carrier family 23 member 1 (sprot)

A solute carrier family 23 member 1 that is encoded in the genome of human.


ATS1_HUMAN A disintegrin and metalloproteinase with thrombospondin motifs 1 (sprot)

An a disintegrin and metalloproteinase with thrombospondin motifs 1 that is encoded in the genome of human.


SMBT1_HUMAN Scm-like with four MBT domains protein 1 (sprot)

An Scm-like with four MBT domains protein 1 that is encoded in the genome of human.


negative regulation of muscle organ development

Any process that stops, prevents, or reduces the frequency, rate or extent of muscle development.


SHPK_HUMAN Sedoheptulokinase (sprot)

A sedoheptulokinase that is encoded in the genome of human.


sedoheptulokinase activity

Catalysis of the reaction: ATP + sedoheptulose = ADP + 2 H+ + sedoheptulose 7-phosphate.


PGAP2_HUMAN Post-GPI attachment to proteins factor 2 (sprot)

A post-GPI attachment to proteins factor 2 that is encoded in the genome of human.


NUFP1_HUMAN FMR1-interacting protein NUFIP1 (sprot)

An FMR1-interacting protein NUFIP1 that is encoded in the genome of human.


AMACR_HUMAN Alpha-methylacyl-CoA racemase (sprot)

An alpha-methylacyl-CoA racemase that is encoded in the genome of human.


alpha-methylacyl-CoA racemase activity

Catalysis of the reaction: (2S)-2-methylacyl-CoA = (2R)-2-methylacyl-CoA.


DDX25_HUMAN ATP-dependent RNA helicase DDX25 (sprot)

An ATP-dependent RNA helicase DDX25 that is encoded in the genome of human.


F153A_HUMAN Protein FAM153A (sprot)

A protein FAM153A that is encoded in the genome of human.


DPP2_HUMAN Dipeptidyl peptidase 2 (sprot)

A dipeptidyl peptidase 2 that is encoded in the genome of human.


GT2D1_HUMAN General transcription factor II-I repeat domain-containing protein 1 (sprot)

A general transcription factor II-I repeat domain-containing protein 1 that is encoded in the genome of human.


transition between slow and fast fiber

The process of conversion of slow-contracting muscle fibers to a faster character. This may involve increasing of contractile rate, fast myosin gene induction, increase in glycolytic metabolic properties, altered electrophysiology and altered innervation. This process also regulates skeletal muscle adapatation.


OPN4_HUMAN Melanopsin (sprot)

A melanopsin that is encoded in the genome of human.


DPOG2_HUMAN DNA polymerase subunit gamma-2, mitochondrial (sprot)

A DNA polymerase subunit gamma-2, mitochondrial that is encoded in the genome of human.


CEIP2_HUMAN Inactive cell surface hyaluronidase CEMIP2 (sprot)

A cell surface hyaluronidase that is encoded in the genome of human.


UBP25_HUMAN Ubiquitin carboxyl-terminal hydrolase 25 (sprot)

A ubiquitin carboxyl-terminal hydrolase 25 that is encoded in the genome of human.


negative regulation of interleukin-17-mediated signaling pathway

Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-17-mediated signaling pathway.


RSP14_HUMAN Radial spoke head 14 homolog (sprot)

A radial spoke head 14 homolog that is encoded in the genome of human.


CLC2D_HUMAN C-type lectin domain family 2 member D (sprot)

A C-type lectin domain family 2 member D that is encoded in the genome of human.


SMPX_HUMAN Small muscular protein (sprot)

A small muscular protein that is encoded in the genome of human.


NARF_HUMAN Nuclear prelamin A recognition factor (sprot)

A nuclear prelamin A recognition factor that is encoded in the genome of human.


BAP29_HUMAN B-cell receptor-associated protein 29 (sprot)

A B-cell receptor-associated protein 29 that is encoded in the genome of human.


TCAL9_HUMAN Transcription elongation factor A protein-like 9 (sprot)

A transcription elongation factor A protein-like 9 that is encoded in the genome of human.


NB5R1_HUMAN NADH-cytochrome b5 reductase 1 (sprot)

An NADH-cytochrome b5 reductase 1 that is encoded in the genome of human.


BI2L1_HUMAN Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 (sprot)

A brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 that is encoded in the genome of human.


S30BP_HUMAN SAP30-binding protein (sprot)

A SAP30-binding protein that is encoded in the genome of human.


ZNHI2_HUMAN Zinc finger HIT domain-containing protein 2 (sprot)

A zinc finger HIT domain-containing protein 2 that is encoded in the genome of human.


SRTD1_HUMAN SERTA domain-containing protein 1 (sprot)

A SERTA domain-containing protein 1 that is encoded in the genome of human.


RPGFL_HUMAN Rap guanine nucleotide exchange factor-like 1 (sprot)

A Rap guanine nucleotide exchange factor-like 1 that is encoded in the genome of human.


MED13_HUMAN Mediator of RNA polymerase II transcription subunit 13 (sprot)

A mediator of RNA polymerase II transcription subunit 13 that is encoded in the genome of human.


PP13_HUMAN Galactoside-binding soluble lectin 13 (sprot)

A galactoside-binding soluble lectin 13 that is encoded in the genome of human.


PFD2_HUMAN Prefoldin subunit 2 (sprot)

A prefoldin subunit 2 that is encoded in the genome of human.


GPN3_HUMAN GPN-loop GTPase 3 (sprot)

A GPN-loop GTPase 3 that is encoded in the genome of human.


S12A6_HUMAN Solute carrier family 12 member 6 (sprot)

A solute carrier family 12 member 6 that is encoded in the genome of human.


PUF60_HUMAN Poly(U)-binding-splicing factor PUF60 (sprot)

A poly(U)-binding-splicing factor PUF60 that is encoded in the genome of human.


AGRE2_HUMAN Adhesion G protein-coupled receptor E2 (sprot)

An adhesion G protein-coupled receptor E2 that is encoded in the genome of human.


NRBP_HUMAN Nuclear receptor-binding protein (sprot)

A nuclear receptor-binding protein that is encoded in the genome of human.


ENOPH_HUMAN Enolase-phosphatase E1 (sprot)

An enolase-phosphatase E1 that is encoded in the genome of human.


Catalysis of the reaction: 2,3-diketo-5-methylthiopentyl-1-phosphate = H+ + 2-hydroxy 3-keto-5-methylthiopentenyl-1-phosphate. 2,3-diketo-5-methylthiopentyl-1-phosphate is also known as DK-MTP-1-P, and 2-hydroxy 3-keto-5-methylthiopentenyl-1-phosphate as HK-MTPenyl-1-P.


Catalysis of the reaction: 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate + H2O = 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + phosphate. 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate is also known as HK-MTPenyl-P, and 1,2-dihydroxy-3-keto-5-methylthiopentene as DHK-MTPene.


acireductone synthase activity

Catalysis of the reactions: 5-(methylthio)-2,3-dioxopentyl phosphate + H2O = 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + phosphate; (1a) 5-(methylthio)-2,3-dioxopentyl phosphate = 2-hydroxy-5-(methylthio)-3-oxopent-1-enyl phosphate; (1b) 2-hydroxy-5-(methylthio)-3-oxopent-1-enyl phosphate + H2O = 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + phosphate.


FEZ2_HUMAN Fasciculation and elongation protein zeta-2 (sprot)

A fasciculation and elongation protein zeta-2 that is encoded in the genome of human.


EVL_HUMAN Ena/VASP-like protein (sprot)

An ena/VASP-like protein that is encoded in the genome of human.


NDUAC_HUMAN NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (sprot)

An NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 that is encoded in the genome of human.


EI2BD_HUMAN Translation initiation factor eIF-2B subunit delta (sprot)

A translation initiation factor eIF-2B subunit delta that is encoded in the genome of human.


VATH_HUMAN V-type proton ATPase subunit H (sprot)

A V-type proton ATPase subunit H that is encoded in the genome of human.


PRAF1_HUMAN Prenylated Rab acceptor protein 1 (sprot)

A prenylated Rab acceptor protein 1 that is encoded in the genome of human.


TAGL3_HUMAN Transgelin-3 (sprot)

A transgelin-3 that is encoded in the genome of human.


M2GD_HUMAN Dimethylglycine dehydrogenase, mitochondrial (sprot)

A dimethylglycine dehydrogenase, mitochondrial that is encoded in the genome of human.


dimethylglycine dehydrogenase activity

Catalysis of the reaction: N,N-dimethylglycine + electron-transfer flavoprotein + H2O = sarcosine + formaldehyde + reduced electron-transfer flavoprotein.


IPO11_HUMAN Importin-11 (sprot)

An importin-11 that is encoded in the genome of human.


TR112_HUMAN Multifunctional methyltransferase subunit TRM112-like protein (sprot)

A multifunctional methyltransferase subunit TRM112-like protein that is encoded in the genome of human.


peptidyl-glutamine methylation

The addition of a methyl group to a glutamine residue in a protein.


GLSL_HUMAN Glutaminase liver isoform, mitochondrial (sprot)

A glutaminase liver isoform, mitochondrial that is encoded in the genome of human.


SCNBA_HUMAN Sodium channel protein type 11 subunit alpha (sprot)

A sodium channel protein type 11 subunit alpha that is encoded in the genome of human.


reflex

An automatic response to a stimulus beginning with a nerve impulse from a receptor and ending with the action of an effector such as a gland or a muscle. Signaling never reaches a level of consciousness.


small intestine smooth muscle contraction

A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry in the intestine between the stomach and the large intestine.


C-fiber

The axon of a dorsal root ganglion cell that are responsive to pain and temperature. C-fibers are small in diameter (0.2-1.5 um) and unmyelinated.


DACH1_HUMAN Dachshund homolog 1 (sprot)

A dachshund homolog 1 that is encoded in the genome of human.


TSP50_HUMAN Probable threonine protease PRSS50 (sprot)

A testis-specific protease-like protein 50 that is encoded in the genome of human.


NCKX2_HUMAN Sodium/potassium/calcium exchanger 2 (sprot)

A sodium/potassium/calcium exchanger 2 that is encoded in the genome of human.


CBPA4_HUMAN Carboxypeptidase A4 (sprot)

A carboxypeptidase A4 that is encoded in the genome of human.


MRM2_HUMAN rRNA methyltransferase 2, mitochondrial (sprot)

An rRNA methyltransferase 2, mitochondrial that is encoded in the genome of human.


Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing 2'-O-methyluridine.


DNAI1_HUMAN Dynein axonemal intermediate chain 1 (sprot)

A dynein axonemal intermediate chain 1 that is encoded in the genome of human.


CTNA3_HUMAN Catenin alpha-3 (sprot)

A catenin alpha-3 that is encoded in the genome of human.


MD2L2_HUMAN Mitotic spindle assembly checkpoint protein MAD2B (sprot)

A mitotic spindle assembly checkpoint protein MAD2B that is encoded in the genome of human.


DNA damage response, signal transduction resulting in transcription

biolink:Pathway biolink:BiologicalProcess biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:OntologyClass biolink:Occurrent biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

A cascade of processes initiated in response to the detection of DNA damage, and resulting in the induction of transcription.


CYH4_HUMAN Cytohesin-4 (sprot)

A cytohesin-4 that is encoded in the genome of human.


XPO7_HUMAN Exportin-7 (sprot)

An exportin-7 that is encoded in the genome of human.


SLAF5_HUMAN SLAM family member 5 (sprot)

A SLAM family member 5 that is encoded in the genome of human.


negative regulation of granulocyte macrophage colony-stimulating factor production

Any process that stops, prevents, or reduces the frequency, rate, or extent of granulocyte macrophage colony-stimulating factor production.


LCMT1_HUMAN Leucine carboxyl methyltransferase 1 (sprot)

A leucine carboxyl methyltransferase 1 that is encoded in the genome of human.


protein C-terminal leucine carboxyl O-methyltransferase activity

Catalysis of the reaction: S-adenosyl-L-methionine + protein L-leucine = S-adenosyl-L-homocysteine + protein L-leucine methyl ester. This modification occurs only at the oxygen atoms of the free alpha carboxyl group of a leucine residue at the C-terminus of the protein.


VPS51_HUMAN Vacuolar protein sorting-associated protein 51 homolog (sprot)

A vacuolar protein sorting-associated protein 51 that is encoded in the genome of human.


ZN639_HUMAN Zinc finger protein 639 (sprot)

A zinc finger protein 639 that is encoded in the genome of human.


ZN230_HUMAN Zinc finger protein 230 (sprot)

A zinc finger protein 230 that is encoded in the genome of human.


TEKT2_HUMAN Tektin-2 (sprot)

A tektin-2 that is encoded in the genome of human.


MUTYH_HUMAN Adenine DNA glycosylase (sprot)

An adenine DNA glycosylase MUTYH that is encoded in the genome of human.


BAZ2B_HUMAN Bromodomain adjacent to zinc finger domain protein 2B (sprot)

A bromodomain adjacent to zinc finger domain protein 2B that is encoded in the genome of human.


BAZ2A_HUMAN Bromodomain adjacent to zinc finger domain protein 2A (sprot)

A bromodomain adjacent to zinc finger domain protein 2A that is encoded in the genome of human.


BAZ1B_HUMAN Tyrosine-protein kinase BAZ1B (sprot)

A bromodomain adjacent to zinc finger domain protein 1B that is encoded in the genome of human.


histone H2AXY142 kinase activity

Catalysis of the reaction: histone H2AX-tyrosine (position 142) + ATP = (histone H2AX-phosphotyrosine (position 142) + ADP. This reaction is the addition of a phosphate group to the serine residue at position 142 of histone variant H2AX.


PS1C2_HUMAN Psoriasis susceptibility 1 candidate gene 2 protein (sprot)

A psoriasis susceptibility 1 candidate gene 2 protein that is encoded in the genome of human.


SO3A1_HUMAN Solute carrier organic anion transporter family member 3A1 (sprot)

A solute carrier organic anion transporter family member 3A1 that is encoded in the genome of human.


KLF15_HUMAN Krueppel-like factor 15 (sprot)

A krueppel-like factor 15 that is encoded in the genome of human.


ATIF1_HUMAN ATPase inhibitor, mitochondrial (sprot)

An ATPase inhibitor, mitochondrial that is encoded in the genome of human.


HERC5_HUMAN E3 ISG15--protein ligase HERC5 (sprot)

An E3 ISG15--protein ligase HERC5 that is encoded in the genome of human.


PKR-mediated signaling

A series of reactions in which a signal is passed on to downstream proteins within the cell via PKR (also known as EIF2AK2), an intracellular protein kinase that is activated by stress signals or upon binding to double-stranded RNA (dsRNA), followed by autophosphorylation. PKR plays a role in the antiviral response, phosphorylating proteins such as the translation initiation factor eIF2 to inhibit protein synthesis during viral infection. Begins with activation of PKR activity, and ends with regulation of a downstream cellular process, e.g. regulation of transcription or inhibition of translation.


ZN107_HUMAN Zinc finger protein 107 (sprot)

A zinc finger protein 107 that is encoded in the genome of human.


DS13B_HUMAN Dual specificity protein phosphatase 13B (sprot)

A dual specificity protein phosphatase 13 (human), isoforms 1 and 4.


ZDHC2_HUMAN Palmitoyltransferase ZDHHC2 (sprot)

A palmitoyltransferase ZDHHC2 that is encoded in the genome of human.


KAD3_HUMAN GTP:AMP phosphotransferase AK3, mitochondrial (sprot)

A GTP:AMP phosphotransferase, mitochondrial that is encoded in the genome of human.


ITP metabolic process

The chemical reactions and pathways involving ITP, inosine triphosphate.


UTP metabolic process

The chemical reactions and pathways involving UTP, uridine (5'-)triphosphate.


DAPK2_HUMAN Death-associated protein kinase 2 (sprot)

A death-associated protein kinase 2 that is encoded in the genome of human.


positive regulation of eosinophil chemotaxis

Any process that activates or increases the frequency, rate or extent of eosinophil chemotaxis.


autophagosome lumen

The volume enclosed within the autophagosome double-membrane.


TEFF2_HUMAN Tomoregulin-2 (sprot)

A tomoregulin-2 that is encoded in the genome of human.


SCOC_HUMAN Short coiled-coil protein (sprot)

A short coiled-coil protein that is encoded in the genome of human.


KIF25_HUMAN Kinesin-like protein KIF25 (sprot)

A kinesin-like protein KIF25 that is encoded in the genome of human.


negative regulation of mitotic centrosome separation

Any process that stops, prevents, or reduces the frequency, rate or extent of centrosome separation.


PHF11_HUMAN PHD finger protein 11 (sprot)

A PHD finger protein 11 that is encoded in the genome of human.


FKBPL_HUMAN FK506-binding protein-like (sprot)

An FK506-binding protein-like that is encoded in the genome of human.


regulation of blood vessel branching

Any process that modulates the frequency, rate or extent of blood vessel branching.


LCAP_HUMAN Leucyl-cystinyl aminopeptidase (sprot)

A leucyl-cystinyl aminopeptidase that is encoded in the genome of human.


antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent

The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class I protein complex following intracellular transport via a pathway not requiring TAP (transporter associated with antigen processing). The peptide is typically a fragment of a larger exogenous protein which has been degraded within the cell. Class I here refers to classical class I molecules.


BTNL2_HUMAN Butyrophilin-like protein 2 (sprot)

A butyrophilin-like protein 2 that is encoded in the genome of human.


MBD1_HUMAN Methyl-CpG-binding domain protein 1 (sprot)

A methyl-CpG-binding domain protein 1 that is encoded in the genome of human.


SIX4_HUMAN Homeobox protein SIX4 (sprot)

A homeobox protein SIX4 that is encoded in the genome of human.


CNOT7_HUMAN CCR4-NOT transcription complex subunit 7 (sprot)

A CCR4-NOT transcription complex subunit 7 that is encoded in the genome of human.


SPB13_HUMAN Serpin B13 (sprot)

A serpin B13 that is encoded in the genome of human.


negative regulation of keratinocyte apoptotic process

Any process that stops, prevents or reduces the frequency, rate or extent of keratinocyte apoptotic process.


VAX2_HUMAN Ventral anterior homeobox 2 (sprot)

A ventral anterior homeobox 2 that is encoded in the genome of human.


PLXA1_HUMAN Plexin-A1 (sprot)

A plexin-A1 that is encoded in the genome of human.


KCNG1_HUMAN Potassium voltage-gated channel subfamily G member 1 (sprot)

A voltage-gated potassium channel KCNG1 that is encoded in the genome of human.


RWD2A_HUMAN RWD domain-containing protein 2A (sprot)

An RWD domain-containing protein 2A that is encoded in the genome of human.


TSYL4_HUMAN Testis-specific Y-encoded-like protein 4 (sprot)

A testis-specific Y-encoded-like protein 4 that is encoded in the genome of human.


GGT7_HUMAN Glutathione hydrolase 7 (sprot)

A glutathione hydrolase 7 that is encoded in the genome of human.


SIA7B_HUMAN Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 (sprot)

An alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 that is encoded in the genome of human.


RABX5_HUMAN Rab5 GDP/GTP exchange factor (sprot)

A Rab5 GDP/GTP exchange factor that is encoded in the genome of human.


dendritic transport

The directed movement of organelles or molecules along microtubules in dendrites.


negative regulation of Kit signaling pathway

Any process that stops, prevents or reduces the frequency, rate or extent of Kit signaling pathway.


GP160_HUMAN Probable G-protein coupled receptor 160 (sprot)

A probable G-protein coupled receptor 160 that is encoded in the genome of human.


MAGL2_HUMAN MAGE-like protein 2 (sprot)

A MAGE-like protein 2 that is encoded in the genome of human.


MSRA_HUMAN Mitochondrial peptide methionine sulfoxide reductase (sprot)

A peptide methionine sulfoxide reductase that is encoded in the genome of human.


NAGK_HUMAN N-acetyl-D-glucosamine kinase (sprot)

An N-acetyl-D-glucosamine kinase that is encoded in the genome of human.


N-acetylglucosamine kinase activity

Catalysis of the reaction: N-acetyl-D-glucosamine + ATP = N-acetyl-D-glucosamine 6-phosphate + ADP + 2 H+.


muramyl dipeptide kinase activity

Catalysis of the reaction: ATP + muramyl dipeptide = ADP + H(+) + 6-O-phospho-muramyl dipeptide.


N-acetylmannosamine metabolic process

The chemical reactions and pathways involving N-acetylmannosamine, the acetylated derivative of mannosamine, 2-amino-2-deoxymannose.


CLC4K_HUMAN C-type lectin domain family 4 member K (sprot)

A C-type lectin domain family 4 member K that is encoded in the genome of human.


ANX10_HUMAN Annexin A10 (sprot)

An annexin A10 that is encoded in the genome of human.


ZMYM5_HUMAN Zinc finger MYM-type protein 5 (sprot)

A zinc finger MYM-type protein 5 that is encoded in the genome of human.


HACL1_HUMAN 2-hydroxyacyl-CoA lyase 1 (sprot)

A 2-hydroxyacyl-CoA lyase 1 that is encoded in the genome of human.


carbon-carbon lyase activity

Catalysis of the cleavage of C-C bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond.


2-hydroxyacyl-CoA lyase activity

Catalysis of the reaction: a 2-hydroxy fatty acyl-CoA = a fatty aldehyde + formyl-CoA. The reaction acts on 2-hydroxy-3-methyl-branched fatty acyl-CoA and 2-hydroxy-long-chain fatty acyl-CoA.


2-hydroxyphytanoyl-CoA lyase activity

Catalysis of the reaction: 2-hydroxyphytanoyl-CoA = 2,6,10,14-tetramethylpentadecanal + formyl-CoA.


KCNE5_HUMAN Potassium voltage-gated channel subfamily E regulatory beta subunit 5 (sprot)

A potassium voltage-gated channel subfamily E regulatory beta subunit 5 that is encoded in the genome of human.


KCNG2_HUMAN Potassium voltage-gated channel subfamily G member 2 (sprot)

A voltage-gated potassium channel KCNG2 that is encoded in the genome of human.


STAG3_HUMAN Cohesin subunit SA-3 (sprot)

A cohesin subunit SA-3 that is encoded in the genome of human.


CAD22_HUMAN Cadherin-22 (sprot)

A cadherin-22 that is encoded in the genome of human.


CRLS1_HUMAN Cardiolipin synthase (CMP-forming) (sprot)

A CMP-forming cardiolipin synthase that is encoded in the genome of human.


cardiolipin synthase (CMP-forming)

Catalysis of the reaction: CDP-diacylglycerol + phosphatidylglycerol = CMP + diphosphatidylglycerol.


response to phosphatidylethanolamine

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a phosphatidylethanolamine stimulus.


MCM8_HUMAN DNA helicase MCM8 (sprot)

A DNA helicase MCM8 that is encoded in the genome of human.


TRM6_HUMAN tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6 (sprot)

A tRNA (adenine-N(1)-)-methyltransferase non-catalytic subunit TRM6 that is encoded in the genome of human.


ENPP5_HUMAN Ectonucleotide pyrophosphatase/phosphodiesterase family member 5 (sprot)

An ectonucleotide pyrophosphatase/phosphodiesterase family member 5 that is encoded in the genome of human.


HOOK1_HUMAN Protein Hook homolog 1 (sprot)

A protein Hook homolog 1 that is encoded in the genome of human.


SH3L2_HUMAN SH3 domain-binding glutamic acid-rich-like protein 2 (sprot)

An SH3 domain-binding glutamic acid-rich-like protein 2 that is encoded in the genome of human.


RIMS3_HUMAN Regulating synaptic membrane exocytosis protein 3 (sprot)

A regulating synaptic membrane exocytosis protein 3 that is encoded in the genome of human.


NGAP_HUMAN Ras GTPase-activating protein nGAP (sprot)

A Ras GTPase-activating protein nGAP that is encoded in the genome of human.


regulation of protein activation cascade

Any process that modulates the frequency, rate or extent of protein activation cascade.


MSPD1_HUMAN Motile sperm domain-containing protein 1 (sprot)

A motile sperm domain-containing protein 1 that is encoded in the genome of human.


METRN_HUMAN Meteorin (sprot)

A meteorin that is encoded in the genome of human.


RUSD1_HUMAN RNA pseudouridylate synthase domain-containing protein 1 (sprot)

An RNA pseudouridylate synthase domain-containing protein 1 that is encoded in the genome of human.


GNPTG_HUMAN N-acetylglucosamine-1-phosphotransferase subunit gamma (sprot)

An N-acetylglucosamine-1-phosphotransferase subunit gamma that is encoded in the genome of human.


A protein complex that possesses UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity; the bovine complex contains disulfide-linked homodimers of 166- and 51-kDa subunits and two identical, noncovalently associated 56-kDa subunits.


TSR3_HUMAN 18S rRNA aminocarboxypropyltransferase (sprot)

An 18S rRNA aminocarboxypropyltransferase that is encoded in the genome of human.


18S rRNA aminocarboxypropyltransferase activity

Catalysis of the reaction: N1-methylpseudouridine in 18S rRNA + S-adenosyl-L-methionine = H+ + N1-methyl-N3-[(3S)-3-amino-3-carboxypropyl]pseudouridine in 18S rRNA + S-methyl-5'-thioadenosine.


ZF69B_HUMAN Zinc finger protein 69 homolog B (sprot)

A zinc finger protein 69 homolog B that is encoded in the genome of human.


ERRFI_HUMAN ERBB receptor feedback inhibitor 1 (sprot)

An ERBB receptor feedback inhibitor 1 that is encoded in the genome of human.


response to 1-oleoyl-sn-glycerol 3-phosphate

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 1-oleoyl-sn-glycerol 3-phosphate stimulus.


HAOX1_HUMAN 2-Hydroxyacid oxidase 1 (sprot)

A 2-hydroxyacid oxidase 1 that is encoded in the genome of human.


glyoxylate oxidase activity

Catalysis of the reaction: glyoxylate + H2O + O2 = H2O2 + H+ + oxalate.


glycolate catabolic process

The chemical reactions and pathways resulting in the breakdown of glycolate, the anion of hydroxyethanoic acid (glycolic acid).


ZN391_HUMAN Zinc finger protein 391 (sprot)

A zinc finger protein 391 that is encoded in the genome of human.


KLH21_HUMAN Kelch-like protein 21 (sprot)

A kelch-like protein 21 that is encoded in the genome of human.


chromosome passenger complex localization to spindle midzone

A cellular protein complex localization that acts on a chromosome passenger complex; as a result, the complex is transported to, or maintained in, a specific location at the spindle midzone. A chromosome passenger complex is a protein complex that contains the BIR-domain-containing protein Survivin, Aurora B kinase, INCENP and Borealin, and coordinates various events based on its location to different structures during the course of mitosis. The spindle midzone is the area in the center of the spindle where the spindle microtubules from opposite poles overlap.


LAMP5_HUMAN Lysosome-associated membrane glycoprotein 5 (sprot)

A lysosome-associated membrane glycoprotein 5 that is encoded in the genome of human.


SALL4_HUMAN Sal-like protein 4 (sprot)

A Sal-like protein 4 that is encoded in the genome of human.


S2513_HUMAN Electrogenic aspartate/glutamate antiporter SLC25A13, mitochondrial (sprot)

An electrogenic aspartate/glutamate antiporter SLC25A13, mitochondrial that is encoded in the genome of human.


TBE_HUMAN Tubulin epsilon chain (sprot)

A tubulin epsilon chain that is encoded in the genome of human.


TBD_HUMAN Tubulin delta chain (sprot)

A tubulin delta chain that is encoded in the genome of human.


TSKS_HUMAN Testis-specific serine kinase substrate (sprot)

A testis-specific serine kinase substrate that is encoded in the genome of human.


FBXL7_HUMAN F-box/LRR-repeat protein 7 (sprot)

An F-box/LRR-repeat protein 7 that is encoded in the genome of human.


LEF1_HUMAN Lymphoid enhancer-binding factor 1 (sprot)

A lymphoid enhancer-binding factor 1 that is encoded in the genome of human.


ZN112_HUMAN Zinc finger protein 112 (sprot)

A zinc finger protein 112 that is encoded in the genome of human.


FOXD3_HUMAN Forkhead box protein D3 (sprot)

A forkhead box protein D3 that is encoded in the genome of human.


DBNL_HUMAN Drebrin-like protein (sprot)

A drebrin-like protein that is encoded in the genome of human.


TRIM1_HUMAN Probable E3 ubiquitin-protein ligase MID2 (sprot)

A midline-2 that is encoded in the genome of human.


PURG_HUMAN Purine-rich element-binding protein gamma (sprot)

A purine-rich element-binding protein gamma that is encoded in the genome of human.


DDX41_HUMAN Probable ATP-dependent RNA helicase DDX41 (sprot)

A probable ATP-dependent RNA helicase DDX41 that is encoded in the genome of human.


DCTN4_HUMAN Dynactin subunit 4 (sprot)

A dynactin subunit 4 that is encoded in the genome of human.


TINAG_HUMAN Tubulointerstitial nephritis antigen (sprot)

A tubulointerstitial nephritis antigen that is encoded in the genome of human.


DNM3L_HUMAN DNA (cytosine-5)-methyltransferase 3-like (sprot)

A DNA (cytosine-5)-methyltransferase 3-like that is encoded in the genome of human.


ZN229_HUMAN Zinc finger protein 229 (sprot)

A zinc finger protein 229 that is encoded in the genome of human.


ZN180_HUMAN Zinc finger protein 180 (sprot)

A zinc finger protein 180 that is encoded in the genome of human.


SRTD3_HUMAN SERTA domain-containing protein 3 (sprot)

A SERTA domain-containing protein 3 that is encoded in the genome of human.


OSGI1_HUMAN Oxidative stress-induced growth inhibitor 1 (sprot)

An oxidative stress-induced growth inhibitor 1 that is encoded in the genome of human.


CDC23_HUMAN Cell division cycle protein 23 homolog (sprot)

A cell division cycle protein 23 that is encoded in the genome of human.


APC7_HUMAN Anaphase-promoting complex subunit 7 (sprot)

An anaphase-promoting complex subunit 7 that is encoded in the genome of human.


APC5_HUMAN Anaphase-promoting complex subunit 5 (sprot)

An anaphase-promoting complex subunit 5 that is encoded in the genome of human.


APC4_HUMAN Anaphase-promoting complex subunit 4 (sprot)

An anaphase-promoting complex subunit 4 that is encoded in the genome of human.


ANC2_HUMAN Anaphase-promoting complex subunit 2 (sprot)

An anaphase-promoting complex subunit 2 that is encoded in the genome of human.


HSPB8_HUMAN Heat shock protein beta-8 (sprot)

A heat shock protein beta-8 that is encoded in the genome of human.


GGA2_HUMAN ADP-ribosylation factor-binding protein GGA2 (sprot)

An ADP-ribosylation factor-binding protein GGA2 that is encoded in the genome of human.


GGA1_HUMAN ADP-ribosylation factor-binding protein GGA1 (sprot)

An ADP-ribosylation factor-binding protein GGA1 that is encoded in the genome of human.


STML2_HUMAN Stomatin-like protein 2, mitochondrial (sprot)

A stomatin-like protein 2 that is encoded in the genome of human.


lipid localization

Any process in which a lipid is transported to, or maintained in, a specific location.


CC018_HUMAN Uncharacterized protein C3orf18 (sprot)

An uncharacterized protein C3orf18 that is encoded in the genome of human.


GDF2_HUMAN Growth/differentiation factor 2 (sprot)

A growth/differentiation factor 2 that is encoded in the genome of human.


GBG8_HUMAN Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 (sprot)

A guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 that is encoded in the genome of human.


cellular response to pheromone

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pheromone stimulus.


ZN225_HUMAN Zinc finger protein 225 (sprot)

A zinc finger protein 225 that is encoded in the genome of human.


ZN223_HUMAN Zinc finger protein 223 (sprot)

A zinc finger protein 223 that is encoded in the genome of human.


ZN222_HUMAN Zinc finger protein 222 (sprot)

A zinc finger protein 222 that is encoded in the genome of human.


ZN221_HUMAN Zinc finger protein 221 (sprot)

A zinc finger protein 221 that is encoded in the genome of human.


KCND3_HUMAN Potassium voltage-gated channel subfamily D member 3 (sprot)

A voltage-gated potassium channel KCND3 that is encoded in the genome of human.


FBX2_HUMAN F-box only protein 2 (sprot)

An F-box only protein 2 that is encoded in the genome of human.


NAGPA_HUMAN N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase (sprot)

An N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase that is encoded in the genome of human.


Catalysis of the reaction: glycoprotein N-acetyl-D-glucosaminyl-phospho-D-mannose + H2O = N-acetyl-D-glucosamine + glycoprotein phospho-D-mannose.


TM59L_HUMAN Transmembrane protein 59-like (sprot)

A transmembrane protein 59-like that is encoded in the genome of human.


KS6A6_HUMAN Ribosomal protein S6 kinase alpha-6 (sprot)

A ribosomal protein S6 kinase alpha-6 that is encoded in the genome of human.


negative regulation of embryonic development

Any process that stops, prevents, or reduces the frequency, rate or extent of embryonic development.


ZN580_HUMAN Zinc finger protein 580 (sprot)

A zinc finger protein 580 that is encoded in the genome of human.


NOCT_HUMAN Nocturnin (sprot)

A nocturnin that is encoded in the genome of human.


NADP phosphatase activity

Catalysis of the reaction: H2O + NADP+ = NAD+ + phosphate.


NADPH phosphatase activity

Catalysis of the reaction: NADPH + H2O = NADH + hydrogenphosphate.


VPS28_HUMAN Vacuolar protein sorting-associated protein 28 homolog (sprot)

A vacuolar protein sorting-associated protein 28 that is encoded in the genome of human.


LSM7_HUMAN U6 snRNA-associated Sm-like protein LSm7 (sprot)

A U6 snRNA-associated Sm-like protein LSm7 that is encoded in the genome of human.


ING1_HUMAN Inhibitor of growth protein 1 (sprot)

An inhibitor of growth protein 1 that is encoded in the genome of human.


ZPI_HUMAN Protein Z-dependent protease inhibitor (sprot)

A protein Z-dependent protease inhibitor that is encoded in the genome of human.


CCNL1_HUMAN Cyclin-L1 (sprot)

A cyclin-L1 that is encoded in the genome of human.


DBR1_HUMAN Lariat debranching enzyme (sprot)

A lariat debranching enzyme that is encoded in the genome of human.


RNA lariat debranching enzyme activity

Catalysis of the hydrolysis of branched RNA structures that contain vicinal 2'-5'- and 3'-5'-phosphodiester bonds at a branch point nucleotide.


RNA fragment catabolic process

The chemical reactions and pathways resulting in the breakdown of a fragment of RNA, such as excised introns or sequences removed from ribosomal RNA during processing.


TASOR_HUMAN Protein TASOR (sprot)

A protein TASOR that is encoded in the genome of human.


FEM1B_HUMAN Protein fem-1 homolog B (sprot)

A protein fem-1 homolog B that is encoded in the genome of human.


JUPI1_HUMAN Jupiter microtubule associated homolog 1 (sprot)

A jupiter microtubule associated homolog 1 that is encoded in the genome of human.


UBP21_HUMAN Ubiquitin carboxyl-terminal hydrolase 21 (sprot)

A ubiquitin carboxyl-terminal hydrolase 21 that is encoded in the genome of human.


DKKL1_HUMAN Dickkopf-like protein 1 (sprot)

A dickkopf-like protein 1 that is encoded in the genome of human.


FBX10_HUMAN F-box only protein 10 (sprot)

An F-box only protein 10 that is encoded in the genome of human.


FBX9_HUMAN F-box only protein 9 (sprot)

An F-box only protein 9 that is encoded in the genome of human.


FBX3_HUMAN F-box only protein 3 (sprot)

An F-box only protein 3 that is encoded in the genome of human.


FBXL5_HUMAN F-box/LRR-repeat protein 5 (sprot)

An F-box/LRR-repeat protein 5 that is encoded in the genome of human.


FBXL4_HUMAN F-box/LRR-repeat protein 4 (sprot)

An F-box/LRR-repeat protein 4 that is encoded in the genome of human.


AKA11_HUMAN A-kinase anchor protein 11 (sprot)

An A-kinase anchor protein 11 that is encoded in the genome of human.


RCAN3_HUMAN Calcipressin-3 (sprot)

A calcipressin-3 that is encoded in the genome of human.