splicing regulator SDE2 isoform h3 (human)

A splicing regulator SDE2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q6IQ49-3.


lymphocyte antigen 86

A protein that is a translation product of the human LY86 gene or a 1:1 ortholog thereof.


inter-alpha-trypsin inhibitor heavy chain H1 O-glycosylated 3 (human)

An inter-alpha-trypsin inhibitor heavy chain H1 (human) that has been O-glycosylated at the residue equivalent to Thr-653 of the amino acid sequence represented by UniProtKB:P19827-1, in which the glycan structure is represented by GlyTouCan:G10225UW. Example: UniProtKB:P19827-1, Thr-653, MOD:00005~GNO:G10225UW.


voltage-gated potassium channel subunit KCNQ1 sequence variant Y315C (human)

A potassium voltage-gated channel subfamily KQT member 1 (human) that has a Cys residue at the position equivalent to Tyr-315 of the amino acid sequence represented by UniProtKB:P51787-1. Example: UniProtKB:P51787-1, Tyr-315, CHEBI:29950.


alpha-N-acetylgalactosaminidase

A protein that is a translation product of the human NAGA gene or a 1:1 ortholog thereof.


histone H3.3, initiator methionine removed phosphorylated 4 (human)

A histone H3.3 (human) that has had the initiator methionine removed and that has been phosphorylated on the residue at the position equivalent to Ser-32 of the amino acid sequence represented by UniProtKB:P84243. UniProtKB:P84243, 2-136, Ser-32, MOD:00046.


F-box/LRR-repeat protein 22

A protein that is a translation product of the human FBXL22 gene or a 1:1 ortholog thereof.


Na(+)/H(+) exchange regulatory cofactor with ERM-binding domain

A protein that consists of two copies of the PDZ domain (Pfam:PF00595) and a copy of the EBP50, C-terminal (Pfam:PF09007) domain.


immunoglobulin heavy constant alpha 2 N-glycosylated 26 (human)

An immunoglobulin heavy constant alpha 2 (human) that has been N-glycosylated at the residue equivalent to Asn-205 of the amino acid sequence represented by UniProtKB:P01877-1, in which the glycan composition is represented by GlyTouCan:G72791KH. Example: UniProtKB:P01877-1, Asn-205, MOD:00160~GNO:G72791KH.


zinc finger and SCAN domain-containing protein 5C

A protein that is a translation product of the human ZSCAN5C gene or a 1:1 ortholog thereof.


lysine-specific demethylase 3A

A protein that is a translation product of the human KDM3A gene or a 1:1 ortholog thereof.


periaxin isoform h1 (human)

A periaxin (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9BXM0-1.


transcriptional regulator ERG

A protein that is a translation product of the human ERG gene or a 1:1 ortholog thereof.


tachykinin-4 isoform h2 (human)

A tachykinin-4 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q86UU9-2.


UDP-glucuronosyltransferase 1A5 isoform h2 (human)

A UDP-glucuronosyltransferase 1A5 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P35504-2.


bromodomain and PHD finger-containing protein 3

A protein that is a translation product of the human BRPF3 gene or a 1:1 ortholog thereof.


histone deacetylase 3

A protein that is a translation product of the human HDAC3 gene or a 1:1 ortholog thereof.


A protein that is a translation product of the human DCHS2 gene or a 1:1 ortholog thereof.


forkhead box protein P1 isoform h3 (human)

A forkhead box protein P1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9H334-3.


protein FAM193B isoform h3 (human)

A protein FAM193B (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q96PV7-3.


signal peptide, CUB and EGF-like domain-containing protein 3

A protein that is a translation product of the human SCUBE3 gene or a 1:1 ortholog thereof.


N-chimaerin isoform hAlpha-1 (human)

An N-chimaerin (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P15882-2.


probable arginine--tRNA ligase, mitochondrial isoform 1 (human)

A probable arginine--tRNA ligase, mitochondrial isoform 1 that is encoded in the genome of human.


zinc finger protein 483

A protein that is a translation product of the human ZNF483 gene or a 1:1 ortholog thereof.


coiled-coil domain-containing protein 120

A protein that is a translation product of the human CCDC120 gene or a 1:1 ortholog thereof.


potassium voltage-gated channel subfamily KQT member 2 isoform 3 (human)

A voltage-gated potassium channel subunit KCNQ2 isoform 3 that is encoded in the genome of human.


probable tRNA methyltransferase 9B

A protein that is a translation product of the human TRMT9B gene or a 1:1 ortholog thereof.


adenylate cyclase type 1

A protein that is a translation product of the human ADCY1 gene or a 1:1 ortholog thereof.


neutrophil gelatinase-associated lipocalin, signal peptide removed form (human)

A neutrophil gelatinase-associated lipocalin (human) that has had the signal peptide removed. UniProtKB:P80188, 21-198.


microtubule-associated protein tau sequence variant G366R (human)

A microtubule-associated protein tau sequence variant (human) that has an Arg residue at the position equivalent to Gly-366 of the amino acid sequence represented by UniProtKB:P10636-8 (Tau-F; GLy-683 in PNS-Tau). Example: UniProtKB:P10636-8, Gly-366, CHEBI:29952.


retinoic acid receptor responder protein 1

A protein that is a translation product of the human RARRES1 gene or a 1:1 ortholog thereof.


zinc finger and BTB domain-containing protein 34

A protein that is a translation product of the human ZBTB34 gene or a 1:1 ortholog thereof.


anti-Muellerian hormone type-2 receptor sequence variant R406Q (human)

An anti-Muellerian hormone type-2 receptor (human) that has a Gln residue at the position equivalent to Arg-406 of the amino acid sequence represented by UniProtKB:Q16671-1. Example: UniProtKB:Q16671-1, Arg-406, CHEBI:30011.


shugoshin 2 isoform h2 (human)

A shugoshin 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q562F6-2.


tRNA modification GTPase GTPBP3, mitochondrial isoform 1 (human)

A tRNA modification GTPase GTPBP3, mitochondrial isoform 1 that is encoded in the genome of human.


sodium/bile acid cotransporter 7 isoform h4 (human)

A sodium/bile acid cotransporter 7 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q0GE19-4.


integrin alpha-M, signal peptide removed form (human)

An integrin alpha-M, signal peptide removed form in human. Example: UniProtKB:P11215-1, 17-1152.


extracellular matrix protein 1 isoform h3 (human)

An extracellular matrix protein 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q16610-3.


polymeric immunoglobulin receptor N-glycosylated 2 (human)

A polymeric immunoglobulin receptor (human) that has been N-glycosylated at the residue equivalent to Asn-469 of the amino acid sequence represented by UniProtKB:P01833-1, in which the glycan composition is represented by GlyTouCan:G88374WZ. Example: UniProtKB:P01833-1, Asn-469, MOD:00160~GNO:G88374WZ.


sestrin-3 isoform h2 (human)

A sestrin-3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P58005-4.


Ras-specific guanine nucleotide-releasing factor 1

A protein that is a translation product of the human RASGRF1 gene or a 1:1 ortholog thereof.


ubiquitin carboxyl-terminal hydrolase MINDY-1 isoform h2 (human)

A ubiquitin carboxyl-terminal hydrolase MINDY-1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8N5J2-2.


required for meiotic nuclear division protein 1 homolog isoform h2 (human)

A required for meiotic nuclear division protein 1 homolog (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9NWS8-2.


IQ domain-containing protein N isoform h1 (human)

An IQ domain-containing protein N (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9H0B3-1.


coagulation factor X N-glycosylated 1 (human)

A coagulation factor X (human) that has been N-glycosylated at the residue equivalent to Asn-221 of the amino acid sequence represented by UniProtKB:P00742-1, in which the glycan structure is represented by GlyTouCan:G18938DW. Example: UniProtKB:P00742-1, Asn-221, MOD:00160~GNO:G18938DW.


secretion-regulating guanine nucleotide exchange factor

A protein that is a translation product of the human SERGEF gene or a 1:1 ortholog thereof.


golgin subfamily A member 8R isoform h2 (human)

A golgin subfamily A member 8R (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:I6L899-2.


LETM1 domain-containing protein 1 isoform h5 (human)

A LETM1 domain-containing protein 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q6P1Q0-5.


protein FAM13C

A protein that is a translation product of the human FAM13C gene or a 1:1 ortholog thereof.


membrane progestin receptor gamma isoform 1 (human)

A membrane progestin receptor gamma isoform 1 that is encoded in the genome of human.


tetratricopeptide repeat protein 23 isoform h2 (human)

A tetratricopeptide repeat protein 23 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q5W5X9-2.


sperm-associated antigen 8 isoform h1 (human)

A sperm-associated antigen 8 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q99932-1.


SH2 domain-containing protein 4A isoform h2 (human)

An SH2 domain-containing protein 4A (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9H788-2.


activated CDC42 kinase 1 phosphorylated 1 (human)

An activated CDC42 kinase 1 (human) that has been phosphorylated on the residue at the position equivalent to Tyr-284 of the amino acid sequence represented by UniProtKB:Q07912-1. Example: UniProtKB:Q07912-1, Tyr-284, MOD:00048.


spermatogenesis associated 6-like protein

A protein that is a translation product of the human SPATA6L gene or a 1:1 ortholog thereof.


anti-Muellerian hormone type-2 receptor isoform Delta9/10 (human)

An anti-Muellerian hormone type-2 receptor isoform Delta9/10 that is encoded in the genome of human. This sequence lacks the region encoded by exons 9 and 10, which is part of the protein kinase domain.


olfactory receptor 5K1

A class II olfactory receptor that is a translation product of the human OR5K1 gene or a 1:1 ortholog thereof.


dual specificity protein phosphatase 5

A protein that is a translation product of the human DUSP5 gene or a 1:1 ortholog thereof.


sodium channel protein type 5 subunit alpha isoform h3 (human)

A sodium channel protein type 5 subunit alpha (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q14524-3.


T-complex protein 11 homolog isoform h4 (human)

A T-complex protein 11 homolog (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8WWU5-4.


netrin receptor UNC5C

A protein that is a translation product of the human UNC5C gene or a 1:1 ortholog thereof.


protein MENT O-glycosylated 1 (human)

A protein MENT (human) that has been O-glycosylated at the residue equivalent to Ser-304 of the amino acid sequence represented by UniProtKB:Q9BUN1-1, in which the glycan composition is represented by GlyTouCan:G29068FM. Example: UniProtKB:Q9BUN1-1, Ser-304, MOD:00002~GNO:G29068FM.


tripartite motif-containing protein 55

A tripartite motif-containing protein that is a translation product of the human TRIM55 gene or a 1:1 ortholog thereof.


phosphatidylinositol 3-kinase regulatory subunit gamma isoform h2 (human)

A phosphatidylinositol 3-kinase regulatory subunit gamma (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q92569-2.


RNA-binding Raly-like protein

A protein that is a translation product of the human RALYL gene or a 1:1 ortholog thereof.


protein SFI1 homolog isoform h9 (human)

A protein SFI1 homolog (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:A8K8P3-9.


ATP-dependent RNA helicase DDX39

A protein that is a translation product of the human DDX39A gene or a 1:1 ortholog thereof.


WD repeat-containing protein 19 isoform h2 (human)

A WD repeat-containing protein 19 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8NEZ3-2.


zinc finger protein 700

A protein that is a translation product of the human ZNF700 gene or a 1:1 ortholog thereof.


FAD-dependent oxidoreductase domain-containing protein 1 isoform h2 (human)

An FAD-dependent oxidoreductase domain-containing protein 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q96CU9-2.


zinc finger protein Helios isoform h6 (human)

A zinc finger protein Helios (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9UKS7-6.


ELKS/Rab6-interacting/CAST family member 1 isoform h5 (human)

An ELKS/Rab6-interacting/CAST family member 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8IUD2-5.


BAG family molecular chaperone regulator 3, initiator methionine removed form (human)

A BAG family molecular chaperone regulator 3 (human) that has had the initiator methionine removed. UniProtKB:O95817, 2-575.


myb proto-oncogene protein

A protein that is a translation product of the human MYB gene or a 1:1 ortholog thereof.


MRN complex-interacting protein isoform h3 (human)

An MRN complex-interacting protein (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q6NTE8-3.


6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 isoform h3 (human)

A 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q16877-3.


vitronectin O-glycosylated 6 (human)

A vitronectin (human) that has been O-glycosylated at the residue equivalent to Thr-429 of the amino acid sequence represented by UniProtKB:P04004-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P04004-1, Thr-429, MOD:00005~GNO:G43417UB.


transmembrane emp24 domain-containing protein 3 isoform h2 (human)

A transmembrane emp24 domain-containing protein 3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9Y3Q3-2.


zinc finger protein 804A

A protein that is a translation product of the human ZNF804A gene or a 1:1 ortholog thereof.


Fas-binding factor 1 isoform h1 (human)

A Fas-binding factor 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8TES7-1.


zinc finger protein 90 homolog isoform h1 (human)

A zinc finger protein 90 homolog (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8TF47-1.


glucocorticoid receptor isoform hAlpha-D2 (human)

A glucocorticoid receptor (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P04150-15.


probable palmitoyltransferase ZDHHC24 isoform 1 (human)

A probable palmitoyltransferase ZDHHC24 isoform 1 that is encoded in the genome of human.


fibronectin N-glycosylated 39 (human)

A fibronectin (human) that has been N-glycosylated at the residue equivalent to Asn-528 of the amino acid sequence represented by UniProtKB:P02751-15, in which the glycan composition is represented by GlyTouCan:G60923RB. Example: UniProtKB:P02751-15, Asn-528, MOD:00160~GNO:G60923RB.


ADAM 17 endopeptidase

A protein that is a translation product of the human ADAM17 gene or a 1:1 ortholog thereof.


solute carrier family 45 member 4 isoform h3 (human)

A solute carrier family 45 member 4 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q5BKX6-3.


platelet-derived growth factor with CUB domain

A protein that has a core domain composition consisting of a signal peptide, a CUB domain (Pfam:PF00431), and a C-terminal Platelet-derived growth factor (PDGF) domain (Pfam:PF00341).


SUMO-interacting motif-containing protein 1 isoform h4 (human)

A SUMO-interacting motif-containing protein 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8NDZ2-4.


alpha-1-acid glycoprotein 2 N-glycosylated 11 (human)

An alpha-1-acid glycoprotein 2 (human) that has been N-glycosylated at the residue equivalent to Asn-33 of the amino acid sequence represented by UniProtKB:P19652-1, in which the glycan composition is represented by GlyTouCan:G59626AS. Example: UniProtKB:P19652-1, Asn-33, MOD:00160~GNO:G59626AS.


aquaporin-7 isoform h1 (human)

An aquaporin-7 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O14520-1.


EGF-containing fibulin-like extracellular matrix protein 1 O-glycosylated 13 (human)

An EGF-containing fibulin-like extracellular matrix protein 1 (human) that has been O-glycosylated at the residue equivalent to Thr-88 of the amino acid sequence represented by UniProtKB:Q12805-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:Q12805-1, Thr-88, MOD:00005~GNO:G43417UB.


mitochondrial potassium channel

A protein that is a translation product of the human CCDC51 gene or a 1:1 ortholog thereof.


PHD finger protein 14

A protein that is a translation product of the human PHF14 gene or a 1:1 ortholog thereof.


epididymal sperm-binding protein 1

A protein that is a translation product of the human ELSPBP1 gene or a 1:1 ortholog thereof.


39S ribosomal protein L30, mitochondrial isoform h1 (human)

A 39S ribosomal protein L30, mitochondrial (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8TCC3-1.


Rho guanine nucleotide exchange factor 7 isoform 3 (human)

A Rho guanine nucleotide exchange factor 7 isoform 3 that is encoded in the genome of human.


envoplakin-like protein

A protein that is a translation product of the human EVPLL gene or a 1:1 ortholog thereof.


olfactory receptor 10D3 isoform 1 (human)

An olfactory receptor 958 isoform 1 that is encoded in the genome of human.


coiled-coil domain-containing protein 24 isoform h2 (human)

A coiled-coil domain-containing protein 24 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8N4L8-2.


leukemia inhibitory factor

A protein that is a translation product of the human LIF gene or a 1:1 ortholog thereof.


TATA box-binding protein-associated factor RNA polymerase I subunit B N6-acetyllysine form (human)

A TATA box-binding protein-associated factor RNA polymerase I subunit B (human) that includes at least one N6-acetyllysine. UniProtKB:Q53T94, MOD:00064.


collagen alpha-6(IV) chain

A collagen type IV alpha chain that is a translation product of the human COL4A6 gene or a 1:1 ortholog thereof.


protein arginine N-methyltransferase 1 isoform V1 (human)

A protein arginine N-methyltransferase 1 isoform V1 that is encoded in the genome of human.


RWD domain-containing protein 1 isoform h2 (human)

An RWD domain-containing protein 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9H446-2.


ectodysplasin-A receptor-associated adapter protein isoform A (human)

An ectodysplasin-A receptor-associated adapter protein (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8WWZ3-1.


small nuclear ribonucleoprotein-associated protein N isoform h2 (human)

A small nuclear ribonucleoprotein-associated protein N (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P63162-2.


killer cell immunoglobulin-like receptor 2DS3

A protein that is a translation product of the human KIR2DS3 gene or a 1:1 ortholog thereof.


derlin-3 isoform h4 (human)

A derlin-3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q96Q80-4.


ubiquitin carboxyl-terminal hydrolase 7 isoform h2 (human)

A ubiquitin carboxyl-terminal hydrolase 7 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q93009-2.


fibroblast growth factor receptor 1 isoform h4 (human)

A fibroblast growth factor receptor 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P11362-2.


ubiquitin-conjugating enzyme E2 E2 isoform 1 (human)

A ubiquitin-conjugating enzyme E2 E2 isoform 1 that is encoded in the genome of human.


CAD protein, initiator methionine removed form (human)

A CAD protein (human) that has had the initiator methionine removed. UniProtKB:P27708, 2-2225.


glycoprotein hormones alpha chain N-glycosylated 17 (human)

A glycoprotein hormones alpha chain (human) that has been N-glycosylated at the residue equivalent to Asn-102 of the amino acid sequence represented by UniProtKB:P01215-1, in which the glycan structure is represented by GlyTouCan:G41708PN. Example: UniProtKB:P01215-1, Asn-102, MOD:00160~GNO:G41708PN.


E3 ubiquitin-protein ligase CHIP isoform h2 (human)

An E3 ubiquitin-protein ligase CHIP (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9UNE7-2.


ataxin-3 isoform h1 (human)

An ataxin-3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P54252-1.


protein transport protein Sec24A isoform h1 (human)

A protein transport protein Sec24A (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O95486-1.


immunoglobulin heavy constant alpha 2 N-glycosylated 13 (human)

An immunoglobulin heavy constant alpha 2 (human) that has been N-glycosylated at the residue equivalent to Asn-205 of the amino acid sequence represented by UniProtKB:P01877-1, in which the glycan composition is represented by GlyTouCan:G31986NC. Example: UniProtKB:P01877-1, Asn-205, MOD:00160~GNO:G31986NC.


secretory carrier-associated membrane protein 5 isoform h2 (human)

A secretory carrier-associated membrane protein 5 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8TAC9-2.


heat shock factor protein 2 isoform h1 (human)

A heat shock factor protein 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q03933-1.


testis-expressed protein 11 isoform h1 (human)

A testis-expressed protein 11 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8IYF3-1.


protein mono-ADP-ribosyltransferase PARP11 isoform h3 (human)

A protein mono-ADP-ribosyltransferase PARP11 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9NR21-1.


histone H2A type 2-B, initiator methionine removed citrullinated 1 (human)

A histone H2A type 2-B (human) that has had the initiator methionine removed and that has been citrullinated at the position equivalent to Arg-4 of the amino acid sequence represented by UniProtKB:Q8IUE6. UniProtKB:Q8IUE6, 2-130, Arg-4, MOD:00219.


biglycan O-glycosylated 1 (human)

A biglycan (human) that has been O-glycosylated at the residue equivalent to Thr-56 of the amino acid sequence represented by UniProtKB:P21810-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P21810-1, Thr-56, MOD:00005~GNO:G43417UB.


beclin 1-associated autophagy-related key regulator isoform 1 (human)

A beclin 1-associated autophagy-related key regulator isoform 1 that is encoded in the genome of human.


TGF-beta receptor type-1 sequence variant 11 (human)

A TGF-beta receptor type-1 (human) that has a three-residue deletion at the position equivalent to region 24-26 of the amino acid sequence represented by UniProtKB:P36897-1. UniProtKB:P36897, 1-23, 27-503.


myelodysplastic syndrome 2 translocation-associated protein

A protein that is a translation product of the human MDS2 gene or a 1:1 ortholog thereof.


structure-specific endonuclease subunit SLX1 isoform h2 (human)

A structure-specific endonuclease subunit SLX1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9BQ83-2.


fatty acid CoA ligase Acsl3 isoform 1 (human)

A fatty acid CoA ligase Acsl3 isoform 1 that is encoded in the genome of human.


serine incorporator 5 isoform h4 (human)

A serine incorporator 5 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q86VE9-4.


enhancer of filamentation 1

A protein that is a translation product of the human NEDD9 gene or a 1:1 ortholog thereof.


dynein light chain Tctex-type 3

A protein that is a translation product of the human DYNLT3 gene or a 1:1 ortholog thereof.


putative peptidyl-tRNA hydrolase PTRHD1

A protein that is a translation product of the human PTRHD1 gene or a 1:1 ortholog thereof.


eyes absent homolog 2 isoform h3 (human)

An eyes absent homolog 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O00167-3.


CKLF-like MARVEL transmembrane domain-containing protein 4 isoform h2 (human)

A CKLF-like MARVEL transmembrane domain-containing protein 4 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8IZR5-2.


thyrotropin subunit beta

A glycoprotein hormone beta chain that is a translation product of the human TSHB gene or a 1:1 ortholog thereof.


diacylglycerol kinase eta

A protein that is a translation product of the human DGKH gene or a 1:1 ortholog thereof.


gasdermin-B isoform h1 (human)

A gasdermin-B (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8TAX9-1.


collagen alpha-1(XII) chain O-glycosylated 1 (human)

A collagen alpha-1(XII) chain (human) that has been O-glycosylated at the residue equivalent to Thr-1180 of the amino acid sequence represented by UniProtKB:Q99715-1, in which the glycan composition is represented by GlyTouCan:G53434XO. Example: UniProtKB:Q99715-1, Thr-1180, MOD:00005~GNO:G53434XO.


ubiquitin carboxyl-terminal hydrolase 3

A protein that is a translation product of the human USP3 gene or a 1:1 ortholog thereof.


hydroxysteroid 11-beta-dehydrogenase 1-like protein

A protein that is a translation product of the human HSD11B1L gene or a 1:1 ortholog thereof.


derlin-1, initiator methionine removed form (human)

A derlin-1 (human) that has had the initiator methionine removed. UniProtKB:Q9BUN8, 2-251.


probable oxidoreductase PXDNL

A protein that is a translation product of the human PXDNL gene or a 1:1 ortholog thereof.


interleukin-32 isoform h4 (human)

An interleukin-32 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P24001-4.


RB1-inducible coiled-coil protein 1 isoform h1 (human)

An RB1-inducible coiled-coil protein 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8TDY2-1.


protein FAM161B isoform h1 (human)

A protein FAM161B (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q96MY7-1.


hematopoietic cell signal transducer, signal peptide removed form (human)

A hematopoietic cell signal transducer (human) that has had the signal peptide removed. UniProtKB:Q9UBK5, 19-93.


ceruloplasmin N-glycosylated 72 (human)

A ceruloplasmin (human) that has been N-glycosylated at the residue equivalent to Asn-762 of the amino acid sequence represented by UniProtKB:P00450-1, in which the glycan structure is represented by GlyTouCan:G84467IZ. Example: UniProtKB:P00450-1, Asn-762, MOD:00160~GNO:G84467IZ.


adenomatous polyposis coli protein 2 isoform h3 (human)

An adenomatous polyposis coli protein 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O95996-3.


vacuolar ATPase assembly integral membrane protein VMA21

A protein that is a translation product of the human VMA21 gene or a 1:1 ortholog thereof.


G-protein coupled receptor 39

A rhodopsin-like G-protein coupled receptor that is a translation product of the human GPR39 gene or a 1:1 ortholog thereof.


Ras-related protein Rab-1A

A protein that is a translation product of the human RAB1A gene or a 1:1 ortholog thereof.


Bcl-2-like protein 11 phosphorylated 2 (human)

A Bcl-2-like protein 11 (human) that has been phosphorylated on the residue at the position equivalent to Ser-69 of the amino acid sequence represented by UniProtKB:O43521. UniProtKB:O43521, Ser-69, MOD:00046.


alpha- and gamma-adaptin-binding protein p34

A protein that is a translation product of the human AAGAB gene or a 1:1 ortholog thereof.


synaptic vesicle glycoprotein 2A isoform h2 (human)

A synaptic vesicle glycoprotein 2A (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q7L0J3-2.


microtubule-associated protein 6 isoform h3 (human)

A microtubule-associated protein 6 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q96JE9-3.


nuclear pore complex protein Nup214

A protein that is a translation product of the human NUP214 gene or a 1:1 ortholog thereof.


fragile X messenger ribonucleoprotein 1 isoform h1 (human)

A fragile X messenger ribonucleoprotein 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q06787-2.


KN motif and ankyrin repeat domain-containing protein 1 isoform h1 (human)

A KN motif and ankyrin repeat domain-containing protein 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q14678-1.


collagen alpha-1(XXVIII) chain O-glycosylated 2 (human)

A collagen alpha-1(XXVIII) chain (human) that has been O-glycosylated at the residue equivalent to Thr-1054 of the amino acid sequence represented by UniProtKB:Q2UY09-1, in which the glycan composition is represented by GlyTouCan:G53434XO. Example: UniProtKB:Q2UY09-1, Thr-1054, MOD:00005~GNO:G53434XO.


iodotyrosine deiodinase 1 isoform h4 (human)

An iodotyrosine deiodinase 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q6PHW0-4.


MyoD family inhibitor domain-containing protein isoform h2 (human)

A MyoD family inhibitor domain-containing protein (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9P1T7-2.


gibberellin catabolic process

biolink:BiologicalProcess biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:Occurrent biolink:OntologyClass biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

The chemical reactions and pathways resulting in the breakdown of gibberellin. Gibberellins are a class of highly modified terpenes that function as plant growth regulators.


positive regulation of mitotic nuclear envelope disassembly

Any process that activates or increases the frequency, rate or extent of mitotic nuclear envelope disassembly.


4-chlorobenzaldehyde oxidase activity

biolink:MolecularActivity biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:Occurrent biolink:OntologyClass biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

Catalysis of the reaction: 4-chlorobenzaldehyde + 2 H2O = 4-chlorobenzoate + 2 H+ + 2 e-.


1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process

The chemical reactions and pathways resulting in the breakdown of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate.


C-acyltransferase activity

Catalysis of the transfer of an acyl group to a carbon atom on the acceptor molecule.


Catalysis of the reaction: 2-methyl-3-oxohexanoyl-CoA + CoA = propanoyl-CoA + butyryl-CoA.


Catalysis of the reaction: acetyl-CoA + deacetylcephalosporin C = cephalosporin C + CoA.


formate C-acetyltransferase activity

Catalysis of the reaction: acetyl-CoA + formate = CoA + pyruvate.


C-palmitoyltransferase activity

Catalysis of the transfer of a palmitoyl group to a carbon atom on the acceptor molecule.


Catalysis of the reaction: S-adenosyl-L-methionine + dTDP-3-N-methylamino-4-oxo-2,3,6-trideoxy-alpha-D-glucose <=> S-adenosyl-L-homocysteine + dTDP-3-N,N-dimethylamino-4-oxo-2,3,6-trideoxy-alpha-D-glucose + H+.


nuclear membrane fusion

The joining of 2 or more lipid bilayer membranes that surround the nucleus.


nuclear outer membrane organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear outer membrane.


sperm nuclear envelope removal

Removal of the sperm nuclear envelope, allowing entry of maternal factors into the sperm nucleus.


nuclear membrane fusion involved in karyogamy

The joining of 2 or more lipid bilayer membranes that surround the nucleus during the creation of a single nucleus from multiple nuclei.


heterochromatin island

biolink:CellularComponent biolink:AnatomicalEntity biolink:OrganismalEntity biolink:BiologicalEntity biolink:NamedThing biolink:PhysicalEssence biolink:SubjectOfInvestigation biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

A region of facultative heterochromatin formed dynamically at specific loci in response to environmental signals, independently of RNAi.


extracellular matrix organization in marginal zone involved in cerebral cortex radial glia guided migration

The process that leads to the deposition of extracellular matrix signals in the marginal zone of the developing cerebral cortex. This extracellular matrix controls the movement of migrating cells. In mammals, the matrix is modified by Cajal-Retzius cells.


(Z,E)-alpha- farnesene synthase activity

Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = (Z,E)-alpha-farnesene + diphosphoric acid.


wing and notum subfield formation

The regionalization process that subdivides the wing imaginal disc into the wing and notum (body wall) subfields, thus determining whether cells ultimately differentiate wing or notum-specific structures.


proplastid

The precursor of other plastids.


cellular response to N-acetyl-D-glucosamine

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an N-acetyl-D-glucosamine stimulus.


response to N-acetyl-D-glucosamine

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an N-acetyl-D-glucosamine stimulus.


response to chondroitin 6'-sulfate

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chondroitin 6'-sulfate stimulus.


cellular response to chondroitin 6'-sulfate

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chondroitin 6'-sulfate stimulus.


metanephric glomerular endothelium development

The process whose specific outcome is the progression of the metanephric glomerular endothelium over time, from its formation to the mature structure. The metanephric glomerular endothelium is an epithelial tissue that covers the internal surfaces of the glomerulus of the metanephros.


mesonephric glomerular epithelium development

The process whose specific outcome is the progression of the mesonephric glomerular epithelium over time, from its formation to the mature structure. The mesonephric glomerular epithelium is an epithelial tissue that covers the outer surfaces of the glomerulus in the mesonephros. The mesonephric glomerular epithelium consists of both parietal and visceral epithelium. Mesonephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. A mesonephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the mesonephros.


metanephric glomerular epithelium development

The process whose specific outcome is the progression of the metanephric glomerular epithelium over time, from its formation to the mature structure. The metanephric glomerular epithelium is an epithelial tissue that covers the outer surfaces of the glomerulus in the metanephros. The metanephric glomerular epithelium consists of both parietal and visceral epithelium. Metanephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. A metanephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the metanephros.


regulation of myofibril number

Any process that modulates the number of myofibrils. A myofibril is the contractile element of skeletal and cardiac muscle. It is a long, highly organized bundle of actin, myosin, and other proteins that contracts by a sliding filament mechanism.


geissoschizine dehydrogenase activity

Catalysis of the reaction: geissoschizine + NADP+ = 4,21-dehydrogeissoschizine + H+ + NADPH.


growth factor complex

A protein complex that has growth factor activity.


phosphatidylcholine biosynthesis from choline and CDP-diacylglycerol

The phosphatidylcholine biosynthetic process that involves a one-step direct condensation of choline with CDP-diacylglycerol to form phosphatidylcholine.


cellular response to red light

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a red light stimulus. Red light is electromagnetic radiation of wavelength of 580-700nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs.


response to red light

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a red light stimulus. Red light is electromagnetic radiation of wavelength of 580-700nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs.


response to photoperiod, red light

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a red light photoperiod stimulus. Red light is electromagnetic radiation of wavelength of 580-700nm.


response to very low fluence red light stimulus

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a very low fluence red light stimulus. Red light is electromagnetic radiation of wavelength of 580-700nm. Very low fluence red light is defined in this case as short pulses of red light followed by darkness, providing light levels of less than 0.001 mmol/m2/sec.


red light signaling pathway

biolink:Pathway biolink:BiologicalProcess biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:OntologyClass biolink:Occurrent biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

The series of molecular signals initiated upon sensing of red light by a photoreceptor molecule. Red light is electromagnetic radiation of wavelength of 580-700nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs.


response to low fluence red light stimulus

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a low fluence red light stimulus. Red light is electromagnetic radiation of wavelength of 580-700nm. Low fluence red light is defined in this case as short pulses of red light followed by darkness, providing a light level of 0.001-0.1 mmol/m2/sec.


Catalysis of the reaction: 2,6-dimethyl-5-methylene-3-oxo-heptanoyl-CoA + CoASH = 3-isopropylbut-3-enoyl-CoA + propanoyl-CoA.


photosynthesis

The synthesis by organisms of organic chemical compounds, especially carbohydrates, from carbon dioxide (CO2) using energy obtained from light rather than from the oxidation of chemical compounds.


hydroxynitrilase activity

Catalysis of the reaction: a hydroxynitrile = cyanide + an aldehyde or ketone.


aliphatic (S)-hydroxynitrile lyase activity

Catalysis of the reaction: an aliphatic (S)-hydroxynitrile = an aliphatic aldehyde or ketone + cyanide.


aromatic (S)-hydroxynitrile lyase activity

Catalysis of the reaction: an aromatic (S)-hydroxynitrile = an aromatic aldehyde + cyanide.


hydroxymandelonitrile lyase activity

Catalysis of the reaction: 4-hydroxymandelonitrile = 4-hydroxybenzaldehyde + hydrocyanate.


aliphatic (R)-hydroxynitrile lyase activity

Catalysis of the reaction: an aliphatic (R)-hydroxynitrile = an aliphatic aldehyde or ketone + hydrogen cyanide.


positive regulation of preblastoderm mitotic cell cycle

Any process that activates or increases the rate or extent of progression through the preblastoderm mitotic cell cycle.


octamethylcyclotetrasiloxane catabolic process to dimethylsilanediol

The anaerobic chemical reactions and pathways resulting in the breakdown of octamethylcyclotetrasiloxane into dimethylsilanediol. The former is a tetramer of the latter.


anaerobic organosilicon metabolic process

The chemical reactions and pathways involving organosilicons, organic compounds that contain silicon, in the absence of oxygen.


protein-glutamic acid ligase activity, elongating

Catalytic reaction :(L-glutamyl)n-L-gamma-glutamyl-L-glutamyl-[protein] + ATP + L-glutamate = (L-glutamyl)n+1-L-gamma-glutamyl-L-glutamyl-[protein] + ADP + H(+) + phosphate.


protein-glutamic acid ligase activity, initiating

Catalytic reaction: ATP + L-glutamate + L-glutamyl-[protein] = ADP + H(+) + L-gamma-glutamyl-L-glutamyl-[protein] + phosphate.


ribosomal protein S6 glutamate-glutamate ligase activity

Catalysis of the reaction: L-glutamate + ATP + a [protein] C-terminal L-glutamate = ADP + hydrogenphosphate + H+ + a [protein] with C-terminal alpha-L-glutamate-alpha-L-glutamate.


ribosomal S6-glutamic acid ligase activity

Catalysis of the posttranslational transfer of one or more glutamic acid residues to the C-terminus of ribosomal protein S6.


Any process that stops, prevents, or reduces the frequency, rate or extent of negative regulation of mitotic spindle assembly checkpoint signaling.


positive regulation of mitotic spindle elongation (spindle phase three)

Any process that activates or increases the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the mitotic spindle during mitotic anaphase B (spindle phase three).


regulation of chronic inflammatory response to antigenic stimulus

Any process that modulates the frequency, rate, or extent of a chronic inflammatory response to an antigenic stimulus.


carotenoid isomerase activity

Catalysis of the isomerization of poly-cis-carotenoids to all-trans-carotenoids.


uredinium development

The process that leads to the formation of a uredinium, a reddish, pustule-like structure formed by a rust fungus and consisting of uredospores.


ocellus pigment metabolic process

The chemical reactions and pathways involving ocellus pigments, any general or particular coloring matter in living organisms, found or utilized in the ocellus, a minute simple eye found in many invertebrates.


ommochrome catabolic process

The chemical reactions and pathways resulting in the breakdown of ommochromes, any of a large group of natural polycyclic pigments commonly found in the Arthropoda, particularly in the ommatidia of the compound eye.


ocellus pigment catabolic process

The chemical reactions and pathways resulting in the breakdown of ocellus pigments, any general or particular coloring matter in living organisms, found or utilized in the ocellus, a minute simple eye found in many invertebrates.


ommochrome biosynthetic process

The chemical reactions and pathways resulting in the formation of ommochromes, any of a large group of natural polycyclic pigments commonly found in the Arthropoda, particularly in the ommatidia of the compound eye.


ocellus pigment biosynthetic process

The chemical reactions and pathways resulting in the formation of ocellus pigments, general or particular coloring matter in living organisms, found or utilized in the ocellus, a minute simple eye found in many invertebrates.


ommochrome metabolic process

The chemical reactions and pathways involving ommochromes, any of a large group of natural polycyclic pigments commonly found in the Arthropoda, particularly in the ommatidia of the compound eye.


negative regulation of spore-bearing organ development

Any process that stops, prevents, or reduces the frequency, rate or extent of spore-bearing organ development, a process in which hyphae grow into special aggregates called fruiting bodies that produce new spores.


negative regulation of telium development

Any process that stops, prevents, or reduces the frequency, rate or extent of telium development, a process that leads to the formation of a teliospore-bearing sorus of the rust fungi.


negative regulation of aecium development

Any process that stops, prevents, or reduces the frequency, rate or extent of aecium development, a process in which a cuplike structure containing chains of aeciospores is formed.


negative regulation of sporocarp development involved in sexual reproduction

Any process that stops, prevents or reduces the frequency, rate or extent of sporocarp development involved in sexual reproduction.


negative regulation of oogonium development

Any process that stops, prevents, or reduces the frequency, rate or extent of oogonium development, a process that leads to the formation of a female gametangium of oomycetes, containing one or more gametes.


negative regulation of sporangium development

Any process that stops, prevents, or reduces the frequency, rate or extent of sporangium development, a process that leads to the formation of sporangium, a single-celled or many-celled structure in which spores are produced, as in fungi, algae, mosses, and ferns, gymnosperms, angiosperms.


negative regulation of conidiophore development

Any process that stops, prevents, or reduces the frequency, rate or extent of conidiophore development, a process that leads to the formation of a conidiophore. The conidiophore is a specialized hypha that extends aerially from the growth substrate and bears conidia, or asexual spores.


negative regulation of oomycete sporangium development

Any process that stops, prevents, or reduces the frequency, rate or extent of oomycete sporangium development, a process that leads to the formation of oomycete sporangium, a single-celled or many-celled structure that germinates directly to form an infection hypha or differentiate, through specialized cleavage vesicles, into between 10 and 30 zoospores, which is laterally flagellated.


negative regulation of cleistothecium development

Any process that stops, prevents, or reduces the frequency, rate or extent of cleistothecium development, a process that leads to the formation of a cleistothecium. The cleistothecium is a closed sexual fruiting body that contains ascospores in linear asci, characteristic of some filamentous Ascomycete fungi such as members of the genera Aspergillus and Emericella.


negative regulation of basidium development

Any process that stops, prevents, or reduces the frequency, rate or extent of basidium development, a process that leads to the formation of basidium, a small, specialized club-shaped structure typically bearing four basidiospores at the tips of minute projections. The basidium is unique to basidiomycetes and distinguishes them from other kinds of fungi.


negative regulation of zygosporangium development

Any process that stops, prevents, or reduces the frequency, rate or extent of zygosporangium development, a process in which a fruiting body called zygosporangium is formed.


negative regulation of ascus development

Any process that stops, prevents, or reduces the frequency, rate or extent of ascus development, a saclike structure produced by fungi of the phylum Ascomycota (sac fungi) in which sexually produced spores (ascospores), usually four or eight in number, are formed.


negative regulation of sporangium germination

Any process that stops, prevents, or reduces the frequency, rate or extent of sporangium germination.


negative regulation of phialide development

Any process that stops, prevents, or reduces the frequency, rate or extent of phialide development, a process that leads to the formation of phialides. Phialides are specialized cells that bud from the ends of metulae on the conidiophore tip.


negative regulation of uredinium development

Any process that stops, prevents, or reduces the frequency, rate or extent of uredinium development, a process that leads to the formation of a reddish, pustule-like structure formed by a rust fungus and consisting of uredospores.


carboxy-terminal domain protein kinase complex

A protein complex that phosphorylates amino acid residues of RNA polymerase II C-terminal domain repeats; phosphorylation occurs mainly on Ser2 and Ser5.


cyclin B3-CDK2 complex

A protein complex consisting of cyclin B3 and cyclin-dependent kinase 2 (CDK2). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner.


Gin4 complex

A protein complex involved in septin ring formation during mitosis. In Saccharomyces cerevisiae it consists of BNI5, CDC3, CDC10, CDC11, CDC12, GIN4, NAP1 and SHS1. At least 2 GIN4 molecules are involved.


cyclin D1-CDK6 complex

A protein complex consisting of cyclin D1 and cyclin-dependent kinase 6 (CDK6). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner.


MPF complex

A complex consisting of a Cdc2-class (also known as Cdc28) cyclin-dependent kinase and an M-phase cyclin such as S. pombe Cdc13. The MPF complex phosphorylates and activates the anaphase promoting complex (APC).


cyclin A1-CDK1 complex

A protein complex consisting of cyclin A1 and cyclin-dependent kinase 1 (CDK1). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner.


CTDK-1 complex

A positive transcription elongation factor complex that comprises the CDK kinase CTK1 (in budding yeast), Lsk1 (in fission yeast) (corresponding to the Panther PTHR24056:SF39 family), a cyclin and an additional gamma subunit (corresponding to the InterPRO entry IPR024638).


Pho85-Pho80 CDK-cyclin complex

A cyclin dependent kinase (CDK) complex that contains a kinase subunit and a regulatory cyclin subunit. An example of this complex in budding yeast S. cerevisiae consists of the Pho85 kinase and the Pho80 cyclin.


cyclin D3-CDK6 complex

A protein complex consisting of cyclin D3 and cyclin-dependent kinase 6 (CDK6). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner.


ABIN2-NFKB1-MAP3K8 complex

A protein complex that contains the precursor form of NF-kappaB (p105), the NF-kappaB inhibitor ABIN-2, and the kinase TPL-2 (MAP3K8); the complex stabilizes TPL-2 and is involved in signaling in lipopolysaccharide (LPS)-stimulated macrophages.


cyclin B2-CDK1 complex

A protein complex consisting of cyclin B2 and cyclin-dependent kinase 1 (CDK1). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner.


erythromycin catabolic process

The chemical reactions and pathways resulting in the breakdown of erythromycin.


polyketide catabolic process

The chemical reactions and pathways resulting in the breakdown of polyketides, any of a diverse group of natural products synthesized via linear poly-beta-ketones, which are themselves formed by repetitive head-to-tail addition of acetyl (or substituted acetyl) units indirectly derived from acetate (or a substituted acetate) by a mechanism similar to that for fatty acid biosynthesis but without the intermediate reductive steps.


F-9775A catabolic process

The chemical reactions and pathways resulting in the breakdown of F-9775A.


granaticin catabolic process

The chemical reactions and pathways resulting in the breakdown of granaticin.


fonsecin catabolic process

The chemical reactions and pathways resulting in the breakdown of fonsecin.


F-9775B catabolic process

The chemical reactions and pathways resulting in the breakdown of F-9775B.


averantin catabolic process

The chemical reactions and pathways resulting in the breakdown of averantin.


oxytetracycline catabolic process

The chemical reactions and pathways resulting in the breakdown of oxytetracycline.


peptidyl-histidine hydroxylation

The hydroxylation of peptidyl-histidine to form peptidyl-hydroxyhistidine.


cellular response to inositol

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an inositol stimulus.


agmatine deiminase activity

Catalysis of the reaction: agmatine + H2O = N-carbamoylputrescine + NH3.


3'-deoxyribose phosphate lyase activity

Catalysis of the conversion of a 3'-deoxyribose phosphate in DNA to a 3'-phosphate.


mammary gland cord morphogenesis

The process in which anatomical structures of the mammary gland cord are generated and organized. Mammary gland cords form when the mammary gland bud invades the mammary fat.


quercitrin binding

Binding to quercitrin.


regulation of biomineral tissue development

Any process that modulates the frequency, rate or extent of biomineral tissue development, the formation of hard tissues that consist mainly of inorganic compounds.


positive regulation of shell calcification

Any process that activates or increases the frequency, rate or extent of shell calcification.


negative regulation of enamel mineralization

Any process that stops, prevents, or reduces the frequency, rate or extent of enamel mineralization, the deposition of calcium salts in tooth enamel.


regulation of shell calcification

Any process that modulates the frequency, rate or extent of shell calcification.


negative regulation of shell calcification

Any process that stops, prevents or reduces the frequency, rate or extent of shell calcification.


regulation of tooth mineralization

Any process that modulates the frequency, rate or extent of tooth mineralization, the deposition of calcium salts in tooth structures.


regulation of bone mineralization involved in bone maturation

Any process that modulates the frequency, rate or extent of bone mineralization involved in bone maturation.


Catalysis of the reaction: heteroglycan + GDP-mannose = (1->3)-alpha-D-mannosylheteroglycan + GDP.


endonucleolytic cleaveage between SSU-rRNA and LSU-rRNA of tetracistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 4.5S-rRNA, 5S-rRNA)

Endonucleolytic cleavages between the SSU-rRNA and the LSU-rRNA of an rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 4.5S rRNA, and the 5S rRNA in that order from 5' to 3' along the primary transcript. These cleavages liberate tRNAs from the polycistronic transcript as well as separating the SSU and LSU containing transcript. Note that the use of the word tetracistronic refers only to the number of mature rRNA molecules which will be produced from the primary transcript and ignores tRNAs that may also be present within the primary transcript.


gallate catabolic process via gallate dioxygenase activity

The chemical reactions and pathways resulting in the breakdown of gallate, the anion of gallic acid, where the first step is the conversion of gallate to (1E)-4-oxobut-1-ene-1,2,4-tricarboxylate catalyzed by gallate dioxygenase.


aerobic gallate catabolic process

The chemical reactions and pathways resulting in the breakdown of gallate, the anion of gallic acid, in the presence of oxygen.


gallate catabolic process via 2-pyrone-4,6-dicarboxylate

The chemical reactions and pathways resulting in the breakdown of gallate, the anion of gallic acid, via the intermediate 2-pyrone-4,6-dicarboxylate.


chalcone biosynthetic process

The chemical reactions and pathways resulting in the formation of chalcone, phenyl steryl ketone or its hydroxylated derivatives.


hexadecanal biosynthetic process

The chemical reactions and pathways resulting in the formation of hexadecanal, the C16 straight chain aldehyde.


plasma membrane-derived photosystem I

A protein complex located in the plasma membrane-derived thylakoid. The photosystem functions as a light-dependent plastocyanin-ferredoxin oxidoreductase, transferring electrons from plastocyanin to ferredoxin. Examples of this complex are found in bacterial species.


Dsc E3 ubiquitin ligase complex

An E3 ubiquitin ligase complex localized to the ER and Golgi membrane. In fission yeast comprises Dsc1, 2, 3 and 4. Involved in the processes of fission yeast sre1 (human SREBP) transcriptional activator proteolytic cleavage, the multivesicular body (MVB) pathway, and a post-endoplasmic reticulum pathway for protein catabolism.


protein splicing

The post-translational removal of peptide sequences from within a protein sequence.


non-intein-mediated protein splicing

The post-translational removal of peptide sequences from within a protein sequence, by a process not involving inteins.


internal genitalia morphogenesis

The process in which the anatomical structures of the internal genitalia are generated and organized. The internal genitalia are the internal sex organs such as the uterine tube, the uterus and the vagina in female mammals, and the testis, seminal vesicle, ejaculatory duct and prostate in male mammals.


Catalysis of the reaction: S-adenosylmethioninamine + cadaverine = 5'-methylthioadenosine + N-(3-aminopropyl)cadaverine.


peptidoglycan-protein cross-linking via N6-mureinyl-L-lysine

The process of linking a protein to peptidoglycan via the epsilon amino group of lysine to the diaminopimelic acid of the peptidoglycan.


peptidoglycan metabolic process

The chemical reactions and pathways involving peptidoglycans, any of a class of glycoconjugates found only in bacterial cell walls and consisting of strands of glycosaminoglycan cross-linked by oligopeptides to form a huge and rigid network.


peptidoglycan turnover

The continual breakdown and regeneration of peptidoglycan required to maintain the cell wall.


galactosaminoglycan metabolic process

The chemical reactions and pathways involving galactosaminoglycans, any one of a group of polysaccharides that contain amino sugars derived from the galactose.


mucopolysaccharide metabolic process

The chemical reactions and pathways involving mucopolysaccharide.


peptidoglycan biosynthetic process

The chemical reactions and pathways resulting in the formation of peptidoglycans, any of a class of glycoconjugates found in bacterial cell walls.


peptidoglycan-protein cross-linking via L-threonyl-pentaglycyl-murein

The process of linking a protein to peptidoglycan via a carboxy terminal threonine carboxyl group through a pentaglycyl peptide to the lysine or diaminopimelic acid of the peptidoglycan.


peptidoglycan-protein cross-linking via L-alanyl-pentaglycyl-murein

The process of linking a protein to peptidoglycan via a carboxy terminal alanine carboxyl group through a pentaglycyl peptide to the lysine or diaminopimelic acid of the peptidoglycan.


The chemical reactions and pathways resulting in the formation of galactosaminoglycans, any of a group of polysaccharides that contain amino sugars derived from the galactose.


protein-chondroitin sulfate linkage via chondroitin sulfate D-glucuronyl-D-galactosyl-D-galactosyl-D-xylosyl-L-serine

Chondroitin sulfate components are covalently linked to a core glycoprotein via O-glycosidic linkages between xylose and serine residues.


peptidoglycan-protein cross-linking

The process of covalently linking peptidoglycan (murein) to proteins.


Catalysis of the reaction: GDP-beta-L-galactose + alpha-D-glucose 1-phosphate = beta-L-galactose-1-phosphate + GDP-alpha-D-glucose.


saccharopine oxidase activity

Catalysis of the reaction: L-saccharopine + O2 = L-2-aminoadipic 6-semialdehyde + L-glutamate + H2O2.


polygalacturonase activity

Catalysis of the random hydrolysis of (1->4)-alpha-D-galactosiduronic linkages in pectate and other galacturonans.


replicative DNA transposition

Process of transposition in which the existing element is replicated and one of the copies is excised and integrated at a new target site. Also referred to as copy-and-paste transposition.


A SNARE complex that contains synaptotagmin, synaptobrevin 2 (VAMP2), SNAP-25, syntaxin 1a, syntaxin1b, and Unc13b (or orthologs thereof).


cellular response to iron(II) ion

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron(II) ion stimulus.


regulation of chemorepellent activity

Any process that modulates the frequency, rate or extent of chemorepellent activity.


negative regulation of chemorepellent activity

Any process that stops, prevents or reduces the frequency, rate or extent of chemorepellent activity.


positive regulation of chemorepellent activity

Any process that activates or increases the frequency, rate or extent of chemorepellent activity.


L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine

The chemical reactions and pathways resulting in the formation of L-methionine from other compounds, including homoserine, via the intermediates O-succinyl-L-homoserine and cystathionine.


photosystem I antenna complex

The antenna complex of photosystem I. A photosystem has two closely linked components, an antenna containing light-absorbing pigments and a reaction center. Each antenna contains one or more light-harvesting complexes (LHCs).


salt aversion

The specific avoidance actions or reactions of an organism in response to the perception of salt.


larval feeding behavior

Feeding behavior in a larval (immature) organism.


pharyngeal pumping

The contraction and relaxation movements of the pharyngeal muscle that mediate feeding in nematodes.


The chemical reactions and pathways involving poly(5-hydroxyvalerate).


The chemical reactions and pathways involving poly(hydroxyalkanoate).


The chemical reactions and pathways resulting in the formation of poly(3-hydroxyvalerate).


The chemical reactions and pathways resulting in the formation of poly(5-hydroxyvalerate).


The chemical reactions and pathways resulting in the formation of poly-hydroxybutyrate (PHB), a polymer of beta-hydroxybutyrate and a common storage material of prokaryotic cells.


poly(hydroxyvalerate) metabolic process

The chemical reactions and pathways involving poly(hydroxyvalerate).


The chemical reactions and pathways involving poly(3-hydroxyvalerate).


poly(hydroxyalkanoate) biosynthetic process from glucose

The chemical reactions and pathways resulting in the formation of poly(hydroxyalkanoate) from glucose.


poly-hydroxybutyrate metabolic process

The chemical reactions and pathways involving poly-hydroxybutyrate (PHB), a polymer of beta-hydroxybutyrate and a common storage material of prokaryotic cells.


poly(hydroxyalkanoate) biosynthetic process from fatty acid

The chemical reactions and pathways resulting in the formation of poly(hydroxyalkanoate) from fatty acid.


The chemical reactions and pathways resulting in the formation of poly(hydroxyvalerate).


The chemical reactions and pathways resulting in the formation of poly(hydroxyalkanoate).


detection of external biotic stimulus

The series of events in which an external biotic stimulus is detected and converted into a molecular signal. An external biotic stimulus is defined as one caused or produced by a living organism other than the one being stimulated.


detection of parasitic plant

The series of events in which a stimulus from a parasitic plant is received and converted into a molecular signal.


detection of symbiont

The series of events in which a stimulus from a symbiont (an organism living in close physical association with an organism of a different species) is received and converted into a molecular signal. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.


detection of bacterial lipopeptide

The series of events in which a bacterial lipopeptide stimulus is received by a cell and converted into a molecular signal.


detection of other organism

The series of events in which a stimulus from another organism is received and converted into a molecular signal.


detection of symbiotic bacterium

The series of events in which a stimulus from a symbiotic bacterium, a bacterium living in close physical association with another organism, is received and converted into a molecular signal.


detection of protozoan

The series of events in which a stimulus from a protozoan is received and converted into a molecular signal.


detection of molecule of oomycetes origin

The series of events in which a stimulus from a molecule of oomycetes origin is received and converted into a molecular signal.


detection of nematode

The series of events in which a stimulus from a nematode is received and converted into a molecular signal.


detection of oomycetes

The series of events in which a stimulus from an oomycetes is received and converted into a molecular signal.


detection of insect

The series of events in which a stimulus from an insect is received and converted into a molecular signal.


polyketide biosynthetic process

The chemical reactions and pathways resulting in the formation of polyketides, any of a diverse group of natural products synthesized via linear poly-beta-ketones, which are themselves formed by repetitive head-to-tail addition of acetyl (or substituted acetyl) units indirectly derived from acetate (or a substituted acetate) by a mechanism similar to that for fatty acid biosynthesis but without the intermediate reductive steps.


fonsecin biosynthetic process

The chemical reactions and pathways resulting in the formation of fonsecin.


aspyridone A biosynthetic process

The chemical reactions and pathways resulting in the formation of aspyridone A.


mevastatin biosynthetic process

The chemical reactions and pathways resulting in the formation of mevastatin , also known as compactin or ML-236B, and which acts as a potent competitive inhibitor of HMG-CoA reductase.


erythromycin biosynthetic process

The chemical reactions and pathways resulting in the formation of erythromycin.


fumigermin biosynthetic process

The chemical reactions and pathways resulting in the formation of fumigermin, an alpha-pyrone secondary metabolite found in some species of fungi such as Aspergillus fumigatus.


oxytetracycline biosynthetic process

The chemical reactions and pathways resulting in the formation of oxytetracycline.


zearalenone biosynthetic process

The chemical reactions and pathways resulting in the formation of zearalenone, a mycotoxin produced by several Fusarium species, is most commonly found as a contaminant in stored grain and has chronic estrogenic effects on mammals.


tetracycline biosynthetic process

The chemical reactions and pathways resulting in the formation of tetracycline, (4S,4aS,5aS,6S,12aS)-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide, a broad-spectrum antibiotic produced by streptomyces bacteria that blocks binding of aminoacyl tRNA to the ribosomes of both Gram-positive and Gram-negative organisms (and those of organelles).


The chemical reactions and pathways resulting in the formation of dihydroxy naphthalene (DHN)-melanin.


averantin biosynthetic process

The chemical reactions and pathways resulting in the formation of averantin.


(M)-viriditoxin biosynthetic process

The chemical reactions and pathways resulting in the formation of (M)-viriditoxin, a fungal secondary metabolite with antibacterial activity.


granaticin biosynthetic process

The chemical reactions and pathways resulting in the formation of granaticin.


ilicicolin H biosynthetic process

The chemical reactions and pathways resulting in the formation of ilicicolin H, a 4-hydroxy-2-pyridone alkaloid that has potent and broad antifungal activities by inhibiting the mitochondrial respiration chain.


aspyridone B biosynthetic process

The chemical reactions and pathways resulting in the formation of aspyridone B.


epothilone biosynthetic process

The chemical reactions and pathways resulting in the formation of epothilone, a drug obtained from the myxobacteria Sporangium cellulosum that interferes with cell division. Some epothilones are being studied as treatments for cancer.


ansamycin biosynthetic process

The chemical reactions and pathways leading to the formation of ansamycins, any of a group of complex macrolactam compounds characterized by a cyclic structure in which an aliphatic ansa chain forms a bridge between two non-adjacent positions of a cyclic p-system; many exhibit antibacterial, antifungal or antitumor activity.


F-9775A biosynthetic process

The chemical reactions and pathways resulting in the formation of F-9775A.


patulin biosynthetic process

The chemical reactions and pathways resulting in the formation of patulin, an acetate-derived tetraketide mycotoxin produced by several fungal species that shows antimicrobial properties against several bacteria.


macrolide biosynthetic process

The chemical reactions and pathways leading to the formation of macrolides, any of a large group of polyketide compounds that contain a large lactone ring with few or no double bonds and no nitrogen atoms, linked glycosidically to one or more sugar groups. The macrolides include the carbomycins, the erythromycins, oleandomycin, oligomycins, and the spiramycins, and act as antibiotics, mainly against Gram-positive bacteria.


mRNA branch site recognition

Recognition of the pre-mRNA branch site sequence by components of the assembling spliceosome.


positive regulation of microtubule plus-end binding

Any process that activates or increases the frequency, rate or extent of microtubule plus-end binding.


positive regulation of microtubule minus-end binding

Any process that activates or increases the frequency, rate or extent of microtubule minus-end binding.


positive regulation of substance P receptor binding

Any process that activates or increases the frequency, rate or extent of substance P receptor binding.


positive regulation of cytokine activity

Any process that increases the rate, frequency or extent of the activity of a molecule that controls the survival, growth, differentiation and effector function of tissues and cells.


positive regulation of apolipoprotein binding

Any process that activates or increases the frequency, rate or extent of apolipoprotein binding.


positive regulation of actin binding

Any process that activates or increases the frequency, rate or extent of actin binding.


positive regulation of C-C chemokine binding

Any process that activates or increases the frequency, rate or extent of C-C chemokine binding.


positive regulation of protein homodimerization activity

Any process that increases the frequency, rate or extent of protein homodimerization, interacting selectively with an identical protein to form a homodimer.


positive regulation of small GTPase binding

Any process that activates or increases the frequency, rate or extent of small GTPase binding.


positive regulation of growth hormone activity

Any process that activates or increases the frequency, rate or extent of growth hormone activity.


mitochondrial mRNA 5'-end processing

Any process involved in forming the mature 5' end of an mRNA molecule that derives from the mitochondrial genome.


negative regulation of conidium formation

Any process that stops, prevents, or reduces the frequency, rate or extent of conidium formation, a process of producing non-motile spores, called conidia, via mitotic asexual reproduction in higher fungi. Conidia are haploid cells genetically identical to their haploid parent. They are produced by conversion of hyphal elements, or are borne on sporogenous cells on or within specialized structures termed conidiophores, and participate in dispersal of the fungus.


response to cytokinesis checkpoint signaling

A process that occurs in response to signals generated as a result of cytokinesis checkpoint signaling.


regulation of ascospore wall chitin catabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of ascospore wall chitin.


Catalysis of the reaction: 5-hydroxy-2-oxo-4-ureido-2,5-dihydro-1H imidazole-5-carboxylate + H+ = S-allantoin + CO2.


negative regulation of formin-nucleated actin cable assembly

Any process that decreases the rate, frequency, or extent of formin-nucleated actin cable assembly. Formin-nucleated actin cable assembly is the aggregation, arrangement and bonding together of a set of components to form a formin-nucleated actin cable. A formin-nucleated actin cable is an actin filament bundle that consists of short filaments organized into bundles of uniform polarity, and is nucleated by formins.


isoamylase activity

Catalysis of the hydrolysis of alpha-(1,6)-D-glucosidic branch linkages in glycogen, amylopectin and their beta-limits dextrins.


noradrenergic neuron fate commitment involved in brainstem development

The process in which the developmental fate of a cell becomes restricted such that it will develop into a noradrenergic neuron that is part of the brainstem.


peptide cross-linking via 2-(S-L-cysteinyl)-L-phenylalanine

The cross-linking of a cysteine residue to an L-phenylalanine residue to form 2-(S-L-cysteinyl)-L-phenylalanine.


negative regulation of mesenchymal stem cell proliferation

Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal stem cell proliferation.


stomatogastric nervous system development

The process whose specific outcome is the progression of the stomatogastric nervous system over time, from its formation to the mature structure.


renal system development

The process whose specific outcome is the progression of the renal system over time, from its formation to the mature structure. The renal system maintains fluid balance and contributes to electrolyte balance, acid/base balance, and disposal of nitrogenous waste products. In humans, the renal system comprises a pair of kidneys, a pair of ureters, urinary bladder, urethra, sphincter muscle and associated blood vessels.


root system development

The process whose specific outcome is the progression of the root system over time, from its formation to the mature structure.


open tracheal system development

The process whose specific outcome is the progression of an open tracheal system over time, from its formation to the mature structure. An open tracheal system is a respiratory system, a branched network of epithelial tubes that supplies oxygen to target tissues via spiracles. An example of this is found in Drosophila melanogaster.


shoot system development

The process whose specific outcome is the progression of the shoot system over time, from its formation to the mature structure.


preganglionic parasympathetic fiber development

The process whose specific outcome is the progression of a preganglionic parasympathetic fiber over time, from its formation to the mature structure. A preganglionic parasympathetic fiber is a cholinergic axonal fiber projecting from the CNS to a parasympathetic ganglion.


reproductive shoot system development

The process whose specific outcome is the progression of a reproductive shoot system over time, from its formation to the mature structure.


inflorescence development

The process whose specific outcome is the progression of an inflorescence over time, from its formation to the mature structure.


renal system vasculature development

The process whose specific outcome is the progression of vasculature of the renal system over time, from its formation to the mature structure.


kidney vasculature development

The process whose specific outcome is the progression of the vasculature of the kidney over time, from its formation to the mature structure.


electrosensory lateral line system development

The process whose specific outcome is the progression of the electrosensory lateral line system over time, from its formation to the mature structure.


somatic sensory system development

The process whose specific outcome is the progression of a somatic sensory system over time from its formation to the mature structure. Somatic sensory system is the sensory system for the sense of touch and pain.


mechanosensory lateral line system development

The process whose specific outcome is the progression of the mechanosensory lateral line system over time, from its formation to the mature structure. The mechanosensory lateral line system consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the head and body of all fishes and most amphibians. The neuromasts are innervated by several lateral line nerves, which project primarily to the hindbrain. The mechanosensory lateral line system is stimulated by local water displacements and vibrations, and detects propulsion of the fish through the water, as well as facilitating shoaling, prey capture, and predator and obstacle avoidance.


flower development

The process whose specific outcome is the progression of the flower over time, from its formation to the mature structure. The flower is the reproductive structure in a plant, and its development begins with the transition of the vegetative or inflorescence meristem into a floral meristem.


lateral line system development

The process whose specific outcome is the progression of the lateral line system over time, from its formation to the mature structure. The lateral line system is a network of sensory organs (neuromasts) and lateral line nerves located superficially on the skin or just under the skin in fluid-filled canals on the head and body of all fishes and most amphibians. The lateral line system develops from cranial ectodermal placodes situated between the eye and ear.


endocrine system development

Progression of the endocrine system over time, from its formation to a mature structure. The endocrine system is a system of hormones and ductless glands, where the glands release hormones directly into the blood, lymph or other intercellular fluid, and the hormones circulate within the body to affect distant organs. The major glands that make up the human endocrine system are the hypothalamus, pituitary, thyroid, parathryoids, adrenals, pineal body, and the reproductive glands which include the ovaries and testes.


hepaticobiliary system development

The progression of the hepaticobiliary system over time, from its formation to the mature structure. The hepaticobiliary system is responsible for metabolic and catabolic processing of small molecules absorbed from the blood or gut, hormones and serum proteins, detoxification, storage of glycogen, triglycerides, metals and lipid soluble vitamins and excretion of bile. Included are the synthesis of albumin, blood coagulation factors, complement, and specific binding proteins.


shoot regeneration

The regeneration process by which a damaged or lost shoot regrows or re-differentiates. This process may occur via de-differentiation and subsequent reprogramming of somatic cells or activation of existing undifferentiated (meristematic) cells to produce a new shoot meristem and subsequently a new shoot.


anterior lateral line system development

The process whose specific outcome is the progression of the anterior lateral line system over time, from its formation to the mature structure. The anterior lateral line system develops from cranial ectodermal placodes, situated between the eye and the ear, that give rise to both the neuromasts and the anterior lateral line sensory nerves that innervate the neuromasts. The anterior lateral line system consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the head of all fishes and most amphibians and are innervated by several lateral line nerves, which project to the hindbrain. The anterior lateral line system is stimulated by local water displacements and vibrations, and detects propulsion of the fish through the water, as well as facilitating shoaling, prey capture, and predator and obstacle avoidance.


tube lumen cavitation

The formation of a lumen by hollowing out a solid rod or cord.


mammary gland duct cavitation

Creation of the central hole of the mammary gland duct by the hollowing out of a solid rod.


positive regulation of calcium-mediated signaling involved in cellular response to calcium ion

Any positive regulation of calcium-mediated signaling that is involved in cellular response to calcium ion.


pheromone binding

Binding to a pheromone, a substance, or characteristic mixture of substances, that is secreted and released by an organism and detected by a second organism of the same or a closely related species, in which it causes a specific reaction, such as a definite behavioral reaction or a developmental process.


positive regulation of pole plasm oskar mRNA localization

Any process that activates or increases the frequency, rate or extent of the process in which oskar mRNA is transported to, or maintained in, the oocyte pole plasm.


23S rRNA (guanine(745)-N(1))-methyltransferase activity

Catalysis of the reaction: S-adenosyl-L-methionine + guanine(745) in 23S rRNA = N(1)-methylguanine(745) in 23S rRNA + S-adenosyl-L-homocysteine.


L-alanine biosynthetic process via ornithine

The chemical reactions and pathways resulting in the formation of L-alanine, via the intermediate ornithine.


L-alanine biosynthetic process

The chemical reactions and pathways resulting in the formation of L-alanine, the L-enantiomer of 2-aminopropanoic acid, i.e. (2S)-2-aminopropanoic acid.


L-alanine biosynthetic process from pyruvate

The chemical reactions and pathways resulting in the formation of alanine from other compounds, including pyruvate.


viral head-tail joining

Process by which virus heads and tails are attached to each other.


regulation of cardiac muscle cell membrane repolarization

Any process that modulates the establishment or extent of a change in membrane potential in the polarizing direction towards the resting potential in a cardiomyocyte.


negative regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization

Any process that stops, prevents or reduces the frequency, rate or extent of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization.


negative regulation of membrane repolarization during atrial cardiac muscle cell action potential

Any process that stops, prevents or reduces the frequency, rate or extent of membrane repolarization during atrial cardiac muscle cell action potential.


positive regulation of membrane repolarization during cardiac muscle cell action potential

Any process that activates or increases the frequency, rate or extent of membrane repolarization during cardiac muscle cell action potential.


regulation of membrane repolarization during ventricular cardiac muscle cell action potential

Any process that modulates the frequency, rate or extent of membrane repolarization during ventricular cardiac muscle cell action potential.


positive regulation of membrane repolarization during atrial cardiac muscle cell action potential

Any process that activates or increases the frequency, rate or extent of membrane repolarization during atrial cardiac muscle cell action potential.


regulation of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization

Any process that modulates the frequency, rate or extent of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization.


negative regulation of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization

Any process that stops, prevents or reduces the frequency, rate or extent of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization.


negative regulation of membrane repolarization during cardiac muscle cell action potential

Any process that stops, prevents or reduces the frequency, rate or extent of membrane repolarization during cardiac muscle cell action potential.


Catalysis of the reaction: adenosylcobinamide-GDP + alpha-ribazole = GMP + adenosylcobalamin.


peptidyl-methionine racemization

The racemization of peptidyl-methionine.


chiral amino acid racemization

The formation of a mixture of the two possible enantiomers from the D- or L-enantiomer of a chiral amino acid.


peptidyl-tryptophan racemization

The racemization of peptidyl-tryptophan.


peptidyl-leucine racemization

The racemization of peptidyl-leucine.


peptidyl-D-alanine racemization, direct

The racemization of peptidyl-alanine.


peptidyl-D-alanine racemization via peptidyl-L-serine

The dehydration of peptidyl-serine, followed by hydrogenation to produce peptidyl-D-alanine.


peptidyl-threonine racemization

The racemization of peptidyl-L-threo-threonine at the alpha-carbon to form D-allo-threonine. This is coupled with the formation of the cross-link 2-(S-L-cysteinyl)-D-allo-threonine.


peptidyl-D-alanine racemization

The formation of peptidyl-D-alanine, by either racemization or from peptidyl-L-serine.


peptidyl-isoleucine racemization

The racemization of peptidyl-isoleucine.


peptidyl-phenylalanine racemization

The racemization of peptidyl-phenylalanine.


peptidyl-L-amino acid racemization

The process of conversion of a L-amino acid into its enantiomer, the corresponding D-amino acid.


peptidyl-serine racemization

The racemization of peptidyl-serine.


negative regulation of attachment of mitotic spindle microtubules to kinetochore

Any process that stops, prevents or reduces the frequency, rate or extent of attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation.


ascospore wall beta-glucan metabolic process

The chemical reactions and pathways involving beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of ascospores.


ascospore wall (1->3)-beta-D-glucan metabolic process

The chemical reactions and pathways involving (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds, found in the walls of ascospores.


proximal convoluted tubule segment 1 cell differentiation

The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the S1 cells of the kidney as it progresses from its formation to the mature state.


regulation of tight junction disassembly

Any process that modulates the frequency, rate or extent of tight junction disassembly.


negative regulation of vacuole fusion, non-autophagic

Any process that decreases the frequency, rate or extent of the fusion of two vacuole membranes to form a single vacuole.


negative regulation of focal adhesion disassembly

Any process that stops, prevents, or reduces the frequency, rate or extent of a focal adhesion into its constituent components.


positive regulation of mitotic cohesin dsDNA (leading strand) loading

Any process that activates or increases the frequency, rate or extent of mitotic cohesin dsDNA (leading strand) loading.


regulation of beta-catenin-TCF complex assembly

Any process that modulates the frequency, rate or extent of beta-catenin-TCF complex assembly.


regulation of actomyosin structure organization

Any process that modulates the frequency, rate or extent of the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures containing both actin and myosin or paramyosin.


positive regulation of postsynaptic density organization

Any process that activates or increases the frequency, rate or extent of postsynaptic density organization.


negative regulation of telomerase catalytic core complex assembly

Any process that stops, prevents or reduces the frequency, rate or extent of telomerase catalytic core complex assembly.