ZBP1_HUMAN Z-DNA-binding protein 1 (sprot)

A Z-DNA-binding protein 1 that is encoded in the genome of human.


left-handed Z-DNA binding

biolink:MolecularActivity biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:Occurrent biolink:OntologyClass biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

Binding to DNA in the Z form, i.e. a left-handed helix in which the phosphate backbone zigzags.


ABCG4_HUMAN ATP-binding cassette sub-family G member 4 (sprot)

An ATP-binding cassette sub-family G member 4 that is encoded in the genome of human.


SIL1_HUMAN Nucleotide exchange factor SIL1 (sprot)

A nucleotide exchange factor SIL1 that is encoded in the genome of human.


CSRN2_HUMAN Cysteine/serine-rich nuclear protein 2 (sprot)

A cysteine/serine-rich nuclear protein 2 that is encoded in the genome of human.


SDCB2_HUMAN Syntenin-2 (sprot)

A syntenin-2 that is encoded in the genome of human.


METL9_HUMAN Protein-L-histidine N-pros-methyltransferase (sprot)

A protein-L-histidine N-pros-methyltransferase that is encoded in the genome of human.


Catalysis of the reaction: L-histidyl-[protein] + S-adenosyl-L-methionine = N(pros)-methyl-L-histidyl-[protein] + S-adenosyl-L-homocysteine.


APC1_HUMAN Anaphase-promoting complex subunit 1 (sprot)

An anaphase-promoting complex subunit 1 that is encoded in the genome of human.


RPB1C_HUMAN DNA-directed RNA polymerase II subunit RPB11-b2 (sprot)

A DNA-directed RNA polymerase II subunit RPB11-b2 that is encoded in the genome of human.


NXF5_HUMAN Nuclear RNA export factor 5 (sprot)

A nuclear RNA export factor 5 that is encoded in the genome of human.


XYLT2_HUMAN Xylosyltransferase 2 (sprot)

A xylosyltransferase 2 that is encoded in the genome of human.


I2BPL_HUMAN Probable E3 ubiquitin-protein ligase IRF2BPL (sprot)

An enhanced at puberty protein 1 that is encoded in the genome of human.


LPAR5_HUMAN Lysophosphatidic acid receptor 5 (sprot)

A lysophosphatidic acid receptor 5 that is encoded in the genome of human.


GL8D2_HUMAN Glycosyltransferase 8 domain-containing protein 2 (sprot)

A glycosyltransferase 8 domain-containing protein 2 that is encoded in the genome of human.


UN93B_HUMAN Protein unc-93 homolog B1 (sprot)

A protein unc-93 homolog B1 that is encoded in the genome of human.


CYTM1_HUMAN Cysteine-rich and transmembrane domain-containing protein 1 (sprot)

A cysteine-rich and transmembrane domain-containing protein 1 that is encoded in the genome of human.


TRPV6_HUMAN Transient receptor potential cation channel subfamily V member 6 (sprot)

A transient receptor potential cation channel subfamily V member 6 that is encoded in the genome of human.


RPC6_HUMAN DNA-directed RNA polymerase III subunit RPC6 (sprot)

A DNA-directed RNA polymerase III subunit RPC6 that is encoded in the genome of human.


RNAS7_HUMAN Ribonuclease 7 (sprot)

A ribonuclease 7 that is encoded in the genome of human.


NUCKS_HUMAN Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 (sprot)

A nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 that is encoded in the genome of human.


gene conversion

biolink:BiologicalProcess biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:Occurrent biolink:OntologyClass biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

A DNA recombination process that results in the unidirectional transfer of genetic material from a donor sequence to a highly homologous acceptor. The resulting acceptor sequence is identical to that of the donor.


modulation by host of RNA binding by virus

A process in which a host organism modulates the frequency, rate or extent of a viral gene product binding to RNA.


modulation by host of viral RNA-binding transcription factor activity

A process in which a host organism modulates the frequency, rate or extent of the activity of a viral RNA-binding transcription factor.


TMX4_HUMAN Thioredoxin-related transmembrane protein 4 (sprot)

A thioredoxin-related transmembrane protein 4 that is encoded in the genome of human.


GTSFL_HUMAN Gametocyte-specific factor 1-like (sprot)

A gametocyte-specific factor 1-like that is encoded in the genome of human.


KI13A_HUMAN Kinesin-like protein KIF13A (sprot)

A kinesin-like protein KIF13A that is encoded in the genome of human.


ASCC2_HUMAN Activating signal cointegrator 1 complex subunit 2 (sprot)

An activating signal cointegrator 1 complex subunit 2 that is encoded in the genome of human.


REN3A_HUMAN Regulator of nonsense transcripts 3A (sprot)

A regulator of nonsense transcripts 3A that is encoded in the genome of human.


WNT8A_HUMAN Protein Wnt-8a (sprot)

A protein Wnt-8a that is encoded in the genome of human.


WNT5B_HUMAN Protein Wnt-5b (sprot)

A protein Wnt-5b that is encoded in the genome of human.


RBNS5_HUMAN Rabenosyn-5 (sprot)

A rabenosyn-5 that is encoded in the genome of human.


ISCU_HUMAN Iron-sulfur cluster assembly enzyme ISCU (sprot)

An iron-sulfur cluster assembly enzyme ISCU that is encoded in the genome of human.


negative regulation of iron ion import across plasma membrane

Any process that stops, prevents or reduces the frequency, rate or extent of iron ions import across plasma membrane.


GHC2_HUMAN Mitochondrial glutamate carrier 2 (sprot)

A mitochondrial glutamate carrier 2 that is encoded in the genome of human.


TLRN1_HUMAN Talin rod domain-containing protein 1 (sprot)

A talin rod domain-containing protein 1 that is encoded in the genome of human.


N62CL_HUMAN Nucleoporin-62 C-terminal-like protein (sprot)

A nucleoporin-62 C-terminal-like protein that is encoded in the genome of human.


DB129_HUMAN Beta-defensin 129 (sprot)

A beta-defensin 129 that is encoded in the genome of human.


DB127_HUMAN Beta-defensin 127 (sprot)

A beta-defensin 127 that is encoded in the genome of human.


S35B3_HUMAN Adenosine 3'-phospho 5'-phosphosulfate transporter 2 (sprot)

An adenosine 3'-phospho 5'-phosphosulfate transporter 2 that is encoded in the genome of human.


OSBL2_HUMAN Oxysterol-binding protein-related protein 2 (sprot)

An oxysterol-binding protein-related protein 2 that is encoded in the genome of human.


CMIP1_HUMAN Ciliary microtubule inner protein 1 (sprot)

An uncharacterized protein C20orf85 that is encoded in the genome of human.


PED1A_HUMAN PC-esterase domain-containing protein 1A (sprot)

A PC-esterase domain-containing protein 1A that is encoded in the genome of human.


DUS15_HUMAN Dual specificity protein phosphatase 15 (sprot)

A dual specificity protein phosphatase 15 that is encoded in the genome of human.


MYLK2_HUMAN Myosin light chain kinase 2, skeletal/cardiac muscle (sprot)

A myosin light chain kinase 2, skeletal/cardiac muscle that is encoded in the genome of human.


MEGF9_HUMAN Multiple epidermal growth factor-like domains protein 9 (sprot)

A multiple epidermal growth factor-like domains protein 9 that is encoded in the genome of human.


S2551_HUMAN Mitochondrial nicotinamide adenine dinucleotide transporter SLC25A51 (sprot)

A mitochondrial nicotinamide adenine dinucleotide transporter SLC25A51 that is encoded in the genome of human.


aerobic electron transport chain

A process in which a series of electron carriers operate together to transfer electrons from donors such as NADH and FADH2 to oxygen to generate a transmembrane electrochemical gradient.


S6A17_HUMAN Sodium-dependent neutral amino acid transporter SLC6A17 (sprot)

A sodium-dependent neutral amino acid transporter SLC6A17 that is encoded in the genome of human.


RSPH9_HUMAN Radial spoke head protein 9 homolog (sprot)

A radial spoke head protein 9 that is encoded in the genome of human.


ATG5_HUMAN Autophagy protein 5 (sprot)

An autophagy protein 5 that is encoded in the genome of human.


Atg8-family ligase activity

Catalysis of the covalent attachment of the ubiquitin-like protein Atg8 family modifer to phosphatidylethanolamine or phosphatidylserine on a membrane.


negative stranded viral RNA replication

A viral genome replication process where the template genome is negative stranded, single stranded RNA ((-)ssRNA).


otolith development

The process whose specific outcome is the progression of the otolith over time, from its formation to the mature structure.


OPN3_HUMAN Opsin-3 (sprot)

An encephalopsin that is encoded in the genome of human.


detection of light stimulus

The series of events in which a light stimulus (in the form of photons) is received and converted into a molecular signal.


WDR13_HUMAN WD repeat-containing protein 13 (sprot)

A WD repeat-containing protein 13 that is encoded in the genome of human.


AUGN_HUMAN Augurin (sprot)

An augurin that is encoded in the genome of human.


TSN10_HUMAN Tetraspanin-10 (sprot)

A tetraspanin-10 that is encoded in the genome of human.


EPN3_HUMAN Epsin-3 (sprot)

An epsin-3 that is encoded in the genome of human.


EH domain binding

Binding to an EH domain of a protein. The EH stand for Eps15 homology. This was originally identified as a motif present in three copies at the NH2-termini of Eps15 and of the related molecule Eps15R.


MED28_HUMAN Mediator of RNA polymerase II transcription subunit 28 (sprot)

A mediator of RNA polymerase II transcription subunit 28 that is encoded in the genome of human.


O2AG1_HUMAN Olfactory receptor 2AG1 (sprot)

An olfactory receptor 2AG1 that is encoded in the genome of human.


O10A5_HUMAN Olfactory receptor 10A5 (sprot)

An olfactory receptor 10A5 that is encoded in the genome of human.


O10A2_HUMAN Olfactory receptor 10A2 (sprot)

An olfactory receptor 10A2 that is encoded in the genome of human.


O10A4_HUMAN Olfactory receptor 10A4 (sprot)

An olfactory receptor 10A4 that is encoded in the genome of human.


OR2D2_HUMAN Olfactory receptor 2D2 (sprot)

An olfactory receptor 2D2 that is encoded in the genome of human.


CDT1_HUMAN DNA replication factor Cdt1 (sprot)

A DNA replication factor Cdt1 that is encoded in the genome of human.


positive regulation of DNA-templated DNA replication

Any process that activates or increases the frequency, rate or extent of DNA-templated DNA replication.


MAGH1_HUMAN Melanoma-associated antigen H1 (sprot)

A melanoma-associated antigen H1 that is encoded in the genome of human.


ABCG8_HUMAN ATP-binding cassette sub-family G member 8 (sprot)

An ATP-binding cassette sub-family G member 8 that is encoded in the genome of human.


negative regulation of intestinal phytosterol absorption

Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of phytosterols into the blood by absorption from the small intestine.


negative regulation of intestinal cholesterol absorption

Any process that stops, prevents, or reduces the frequency, rate or extent of uptake of cholesterol into the blood by absorption from the intestine.


ABCG5_HUMAN ATP-binding cassette sub-family G member 5 (sprot)

An ATP-binding cassette sub-family G member 5 that is encoded in the genome of human.


EHD4_HUMAN EH domain-containing protein 4 (sprot)

An EH domain-containing protein 4 that is encoded in the genome of human.


GBA3_HUMAN Cytosolic beta-glucosidase (sprot)

A cytosolic beta-glucosidase that is encoded in the genome of human.


scopolin beta-glucosidase activity

Catalysis of the reaction: H2O + scopolin <=> beta-D-glucose + scopoletin.


positive regulation of exo-alpha-sialidase activity

Any process that activates or increases the frequency, rate or extent of exo-alpha-sialidase activity.


S1PR5_HUMAN Sphingosine 1-phosphate receptor 5 (sprot)

A sphingosine 1-phosphate receptor 5 that is encoded in the genome of human.


PORCN_HUMAN Protein-serine O-palmitoleoyltransferase porcupine (sprot)

A protein-serine O-palmitoleoyltransferase porcupine that is encoded in the genome of human.


protein palmitoleylation

The covalent attachment of a palmitoleyl group to a protein.


MMP28_HUMAN Matrix metalloproteinase-28 (sprot)

A matrix metalloproteinase-28 that is encoded in the genome of human.


P2Y12_HUMAN P2Y purinoceptor 12 (sprot)

A P2Y purinoceptor 12 that is encoded in the genome of human.


visual system development

The process whose specific outcome is the progression of the visual system over time, from its formation to the mature structure, including the eye, parts of the central nervous system (CNS) involved in processing of visual inputs, and connecting nerve pathways.


CA021_HUMAN Uncharacterized protein C1orf21 (sprot)

An uncharacterized protein C1orf21 that is encoded in the genome of human.


CAD23_HUMAN Cadherin-23 (sprot)

A cadherin-23 that is encoded in the genome of human.


cochlear hair cell ribbon synapse

biolink:CellularComponent biolink:AnatomicalEntity biolink:OrganismalEntity biolink:BiologicalEntity biolink:NamedThing biolink:PhysicalEssence biolink:SubjectOfInvestigation biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

A ribbon synpase of an auditory hair cell of the cochlear. These ribbon synapses contain spherical synaptic ribbons and lack and arciform density.


KCNH6_HUMAN Potassium voltage-gated channel subfamily H member 6 (sprot)

A voltage-gated potassium channel KCNH6 that is encoded in the genome of human.


SPTN4_HUMAN Spectrin beta chain, non-erythrocytic 4 (sprot)

A spectrin beta chain, non-erythrocytic 4 that is encoded in the genome of human.


O51E2_HUMAN Olfactory receptor 51E2 (sprot)

An olfactory receptor 51E2 that is encoded in the genome of human.


CARD9_HUMAN Caspase recruitment domain-containing protein 9 (sprot)

A caspase recruitment domain-containing protein 9 that is encoded in the genome of human.


VP33B_HUMAN Vacuolar protein sorting-associated protein 33B (sprot)

A vacuolar protein sorting-associated protein 33B that is encoded in the genome of human.


vesicle tethering complex

Any protein complex that plays a role in vesicle tethering.


VPS16_HUMAN Vacuolar protein sorting-associated protein 16 homolog (sprot)

A vacuolar protein sorting-associated protein 16 that is encoded in the genome of human.


VPS11_HUMAN Vacuolar protein sorting-associated protein 11 homolog (sprot)

A vacuolar protein sorting-associated protein 11 that is encoded in the genome of human.


IL25_HUMAN Interleukin-25 (sprot)

An interleukin-25 that is encoded in the genome of human.


interleukin-17E receptor binding

Binding to an interleukin-17E receptor.


DCSTP_HUMAN Dendritic cell-specific transmembrane protein (sprot)

A dendritic cell-specific transmembrane protein that is encoded in the genome of human.


SH3L3_HUMAN SH3 domain-binding glutamic acid-rich-like protein 3 (sprot)

An SH3 domain-binding glutamic acid-rich-like protein 3 that is encoded in the genome of human.


AL8A1_HUMAN 2-aminomuconic semialdehyde dehydrogenase (sprot)

A 2-aminomuconic semialdehyde dehydrogenase that is encoded in the genome of human.


Catalysis of the reaction: H2O + NAD+ + 2-aminomuconate semialdehyde = NADH + 2-amino-muconate.


NGN2_HUMAN Neurogenin-2 (sprot)

A neurogenin-2 that is encoded in the genome of human.


CXL16_HUMAN C-X-C motif chemokine 16 (sprot)

A C-X-C motif chemokine 16 that is encoded in the genome of human.


CHST8_HUMAN Carbohydrate sulfotransferase 8 (sprot)

A carbohydrate sulfotransferase 8 that is encoded in the genome of human.


SYT4_HUMAN Synaptotagmin-4 (sprot)

A synaptotagmin-4 that is encoded in the genome of human.


negative regulation of short-term neuronal synaptic plasticity

A process that decreases short-term neuronal synaptic plasticity, the ability of neuronal synapses to change in the short-term as circumstances require. Short-term neuronal synaptic plasticity generally involves increasing or decreasing synaptic sensitivity.


regulation of trans-synaptic signaling by BDNF, modulating synaptic transmission

Any process that modulates the frequency, rate or extent of trans-synaptic signaling by BDNF, modulating synaptic transmission.


regulation of postsynaptic dense core vesicle exocytosis

Any process that modulates the frequency, rate or extent of postsynaptic dense core vesicle exocytosis.


positive regulation of dense core granule exocytosis

Any process that activates or increases the frequency, rate or extent of dense core granule exocytosis.


negative regulation of retrograde trans-synaptic signaling by neuropeptide

Any process that stops, prevents or reduces the frequency, rate or extent of retrograde trans-synaptic signaling by neuropeptide.


S26A1_HUMAN Sulfate anion transporter 1 (sprot)

A sulfate anion transporter 1 that is encoded in the genome of human.


Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sulfate(out) + bicarbonate(in) = sulfate(in) + bicarbonate(out).


GAN_HUMAN Gigaxonin (sprot)

A gigaxonin that is encoded in the genome of human.


LHX5_HUMAN LIM/homeobox protein Lhx5 (sprot)

A LIM/homeobox protein Lhx5 that is encoded in the genome of human.


ARV1_HUMAN Protein ARV1 (sprot)

A protein ARV1 that is encoded in the genome of human.


O52A5_HUMAN Olfactory receptor 52A5 (sprot)

An olfactory receptor 52A5 that is encoded in the genome of human.


O51V1_HUMAN Olfactory receptor 51V1 (sprot)

An olfactory receptor 51V1 that is encoded in the genome of human.


MFTC_HUMAN Mitochondrial folate transporter/carrier (sprot)

A mitochondrial folate transporter/carrier that is encoded in the genome of human.


folate import into mitochondrion

The process in which folic acid is transported from the cytosol into the mitochondrial matrix.


mitochondrial FAD transmembrane transport

The process in which FAD is transported across a mitochondrial membrane, into or out of the mitochondrion.


TARA_HUMAN TRIO and F-actin-binding protein (sprot)

A TRIO and F-actin-binding protein that is encoded in the genome of human.


SEM6A_HUMAN Semaphorin-6A (sprot)

A semaphorin-6A that is encoded in the genome of human.


negative regulation of cell adhesion involved in sprouting angiogenesis

Any process that stops, prevents or reduces the frequency, rate or extent of cell adhesion involved in sprouting angiogenesis.


3BHS7_HUMAN 3 beta-hydroxysteroid dehydrogenase type 7 (sprot)

A 3 beta-hydroxysteroid dehydrogenase type 7 that is encoded in the genome of human.


Catalysis of the reaction: NAD+ + 7-alpha-hydroxycholesterol = NADH + H+ + 7-alpha-hydroxycholest-4-en-3-one.


EPC1_HUMAN Enhancer of polycomb homolog 1 (sprot)

An enhancer of polycomb homolog 1 that is encoded in the genome of human.


CCD68_HUMAN Coiled-coil domain-containing protein 68 (sprot)

A coiled-coil domain-containing protein 68 that is encoded in the genome of human.


SLK_HUMAN STE20-like serine/threonine-protein kinase (sprot)

A STE20-like serine/threonine-protein kinase that is encoded in the genome of human.


TSYL2_HUMAN Testis-specific Y-encoded-like protein 2 (sprot)

A testis-specific Y-encoded-like protein 2 that is encoded in the genome of human.


GO45_HUMAN Golgin-45 (sprot)

A golgin-45 that is encoded in the genome of human.


CXXC4_HUMAN CXXC-type zinc finger protein 4 (sprot)

A CXXC-type zinc finger protein 4 that is encoded in the genome of human.


PPIL3_HUMAN Peptidyl-prolyl cis-trans isomerase-like 3 (sprot)

A peptidyl-prolyl cis-trans isomerase-like 3 that is encoded in the genome of human.


S38A1_HUMAN Sodium-coupled neutral amino acid symporter 1 (sprot)

A sodium-coupled neutral amino acid symporter 1 that is encoded in the genome of human.


positive regulation of L-glutamine import across plasma membrane

Any process that activates or increases the frequency, rate or extent of L-glutamine import into cell.


LRMDA_HUMAN Leucine-rich melanocyte differentiation-associated protein (sprot)

A leucine-rich melanocyte differentiation-associated protein that is encoded in the genome of human.


PDCL3_HUMAN Phosducin-like protein 3 (sprot)

A phosducin-like protein 3 that is encoded in the genome of human.


S6A15_HUMAN Sodium-dependent neutral amino acid transporter B(0)AT2 (sprot)

A sodium-dependent neutral amino acid transporter B(0)AT2 that is encoded in the genome of human.


branched-chain amino acid:sodium symporter activity

Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: branched-chain amino acid(out) + cation(out) = branched-chain amino acid(in) + cation(in).


IF3M_HUMAN Translation initiation factor IF-3, mitochondrial (sprot)

A translation initiation factor IF-3, mitochondrial that is encoded in the genome of human.


TNKS2_HUMAN Poly [ADP-ribose] polymerase tankyrase-2 (sprot)

A poly [ADP-ribose] polymerase tankyrase-2 that is encoded in the genome of human.


TAOK3_HUMAN Serine/threonine-protein kinase TAO3 (sprot)

A serine/threonine-protein kinase TAO3 that is encoded in the genome of human.


TMM60_HUMAN Transmembrane protein 60 (sprot)

A transmembrane protein 60 that is encoded in the genome of human.


RASF4_HUMAN Ras association domain-containing protein 4 (sprot)

A Ras association domain-containing protein 4 that is encoded in the genome of human.


BHMT2_HUMAN S-methylmethionine--homocysteine S-methyltransferase BHMT2 (sprot)

A betaine--homocysteine S-methyltransferase 2 that is encoded in the genome of human.


Catalysis of the reaction: S-adenosyl-L-methionine + L-homocysteine = S-adenosyl-L-homocysteine + L-methionine.


Catalysis of the reaction: S-methyl-L-methionine + L-homocysteine = 2 L-methionine + H+.


S-methylmethionine metabolic process

The chemical reactions and pathways involving S-methyl-methionine (SMM). SMM can be converted to methionine by donating a methyl group to homocysteine, and concurrent operation of this reaction and that mediated by MMT sets up the SMM cycle.


RBGPR_HUMAN Rab3 GTPase-activating protein non-catalytic subunit (sprot)

A Rab3 GTPase-activating protein non-catalytic subunit that is encoded in the genome of human.


ADNP_HUMAN Activity-dependent neuroprotector homeobox protein (sprot)

An activity-dependent neuroprotector homeobox protein that is encoded in the genome of human.


DPH5_HUMAN Diphthine methyl ester synthase (sprot)

A diphthine methyl ester synthase that is encoded in the genome of human.


diphthine synthase activity

Catalysis of the reaction: S-adenosyl-L-methionine + 2-(3-carboxy-3-aminopropyl)-L-histidine = S-adenosyl-L-homocysteine + 2-(3-carboxy-3-(methylammonio)propyl)-L-histidine.


KLK15_HUMAN Kallikrein-15 (sprot)

A kallikrein-15 that is encoded in the genome of human.


KCNN2_HUMAN Small conductance calcium-activated potassium channel protein 2 (sprot)

A small conductance calcium-activated potassium channel protein 2 that is encoded in the genome of human.


RNF39_HUMAN RING finger protein 39 (sprot)

A RING finger protein 39 that is encoded in the genome of human.


TNMD_HUMAN Tenomodulin (sprot)

A tenomodulin that is encoded in the genome of human.


IKZF4_HUMAN Zinc finger protein Eos (sprot)

A zinc finger protein Eos that is encoded in the genome of human.


RBP17_HUMAN Ran-binding protein 17 (sprot)

A Ran-binding protein 17 that is encoded in the genome of human.


DHX36_HUMAN ATP-dependent DNA/RNA helicase DHX36 (sprot)

An ATP-dependent DNA/RNA helicase DHX36 that is encoded in the genome of human.


IPYR2_HUMAN Inorganic pyrophosphatase 2, mitochondrial (sprot)

An inorganic pyrophosphatase 2, mitochondrial that is encoded in the genome of human.


ADAM7_HUMAN Disintegrin and metalloproteinase domain-containing protein 7 (sprot)

A disintegrin and metalloproteinase domain-containing protein 7 that is encoded in the genome of human.


SPNS1_HUMAN Protein spinster homolog 1 (sprot)

A protein spinster homolog 1 that is encoded in the genome of human.


M4A6A_HUMAN Membrane-spanning 4-domains subfamily A member 6A (sprot)

A membrane-spanning 4-domains subfamily A member 6A that is encoded in the genome of human.


MIXL1_HUMAN Homeobox protein MIXL1 (sprot)

A homeobox protein MIXL1 that is encoded in the genome of human.


RM46_HUMAN Large ribosomal subunit protein mL46 (sprot)

A 39S ribosomal protein L46, mitochondrial that is encoded in the genome of human.


CHRD_HUMAN Chordin (sprot)

A chordin that is encoded in the genome of human.


CLC4M_HUMAN C-type lectin domain family 4 member M (sprot)

A C-type lectin domain family 4 member M that is encoded in the genome of human.


HIPK2_HUMAN Homeodomain-interacting protein kinase 2 (sprot)

A homeodomain-interacting protein kinase 2 that is encoded in the genome of human.


I27L2_HUMAN Interferon alpha-inducible protein 27-like protein 2 (sprot)

An interferon alpha-inducible protein 27-like protein 2 that is encoded in the genome of human.


S12A5_HUMAN Solute carrier family 12 member 5 (sprot)

A solute carrier family 12 member 5 that is encoded in the genome of human.


Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: K+(out) + Cl-(out) = K+(in) + Cl-(in).


thermosensory behavior

Behavior that is dependent upon the sensation of temperature.


ZN106_HUMAN Zinc finger protein 106 (sprot)

A zinc finger protein 106 that is encoded in the genome of human.


SO5A1_HUMAN Solute carrier organic anion transporter family member 5A1 (sprot)

A solute carrier organic anion transporter family member 5A1 that is encoded in the genome of human.


NKX24_HUMAN Homeobox protein Nkx-2.4 (sprot)

A homeobox protein Nkx-2.4 that is encoded in the genome of human.


PARL_HUMAN Presenilin-associated rhomboid-like protein, mitochondrial (sprot)

A presenilins-associated rhomboid-like protein, mitochondrial that is encoded in the genome of human.


CDIP1_HUMAN Cell death-inducing p53-target protein 1 (sprot)

A cell death-inducing p53-target protein 1 that is encoded in the genome of human.


MMP27_HUMAN Matrix metalloproteinase-27 (sprot)

A matrix metalloproteinase-27 that is encoded in the genome of human.


PININ_HUMAN Pinin (sprot)

A pinin that is encoded in the genome of human.


RHBG_HUMAN Ammonium transporter Rh type B (sprot)

An ammonium transporter Rh type B that is encoded in the genome of human.


TTYH1_HUMAN Protein tweety homolog 1 (sprot)

A protein tweety homolog 1 that is encoded in the genome of human.


VCX1_HUMAN Variable charge X-linked protein 1 (sprot)

A variable charge X-linked protein 1 that is encoded in the genome of human.


VCX3B_HUMAN Variable charge X-linked protein 3B (sprot)

A variable charge X-linked protein 3B that is encoded in the genome of human.


VCX2_HUMAN Variable charge X-linked protein 2 (sprot)

A variable charge X-linked protein 2 that is encoded in the genome of human.


ATS10_HUMAN A disintegrin and metalloproteinase with thrombospondin motifs 10 (sprot)

An a disintegrin and metalloproteinase with thrombospondin motifs 10 that is encoded in the genome of human.


E41LB_HUMAN Band 4.1-like protein 4B (sprot)

A band 4.1-like protein 4B that is encoded in the genome of human.


TM245_HUMAN Transmembrane protein 245 (sprot)

A transmembrane protein 245 that is encoded in the genome of human.


FOXP1_HUMAN Forkhead box protein P1 (sprot)

A forkhead box protein P1 that is encoded in the genome of human.


regulation of macrophage colony-stimulating factor production

Any process that modulates the frequency, rate or extent of macrophage colony-stimulating factor production.


CRLD1_HUMAN Cysteine-rich secretory protein LCCL domain-containing 1 (sprot)

A cysteine-rich secretory protein LCCL domain-containing 1 that is encoded in the genome of human.


O51B5_HUMAN Olfactory receptor 51B5 (sprot)

An olfactory receptor 51B5 that is encoded in the genome of human.


O51B6_HUMAN Olfactory receptor 51B6 (sprot)

An olfactory receptor 51B6 that is encoded in the genome of human.


O51M1_HUMAN Olfactory receptor 51M1 (sprot)

An olfactory receptor 51M1 that is encoded in the genome of human.


O51J1_HUMAN Olfactory receptor 51J1 (sprot)

An olfactory receptor 51J1 that is encoded in the genome of human.


O51I1_HUMAN Olfactory receptor 51I1 (sprot)

An olfactory receptor 51I1 that is encoded in the genome of human.


O51I2_HUMAN Olfactory receptor 51I2 (sprot)

An olfactory receptor 51I2 that is encoded in the genome of human.


O52D1_HUMAN Olfactory receptor 52D1 (sprot)

An olfactory receptor 52D1 that is encoded in the genome of human.


UBQL3_HUMAN Ubiquilin-3 (sprot)

A ubiquilin-3 that is encoded in the genome of human.


YJ001_HUMAN Putative uncharacterized protein PRO1933 (sprot)


PABP3_HUMAN Polyadenylate-binding protein 3 (sprot)

A polyadenylate-binding protein 3 that is encoded in the genome of human.


GGNB2_HUMAN Gametogenetin-binding protein 2 (sprot)

A gametogenetin-binding protein 2 that is encoded in the genome of human.


P63_HUMAN Tumor protein 63 (sprot)

A tumor protein 63 that is encoded in the genome of human.


ectoderm and mesoderm interaction

A cell-cell signaling process occurring between the two gastrulation-generated layers of the ectoderm and the mesoderm.


epidermal cell division

Any process resulting in the physical partitioning and separation of an epidermal cell, any of the cells making up the epidermis, into daughter cells.


SNX25_HUMAN Sorting nexin-25 (sprot)

A sorting nexin-25 that is encoded in the genome of human.


BACD3_HUMAN BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3 (sprot)

A BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3 that is encoded in the genome of human.


CPVL_HUMAN Probable serine carboxypeptidase CPVL (sprot)

A probable serine carboxypeptidase CPVL that is encoded in the genome of human.


MOD5_HUMAN tRNA dimethylallyltransferase (sprot)

A eukaryotic tRNA dimethylallyltransferase that is encoded in the genome of human.


tRNA dimethylallyltransferase activity

Catalysis of the reaction: dimethylallyl diphosphate + tRNA = diphosphate + tRNA containing 6-dimethylallyladenosine.


CK068_HUMAN UPF0696 protein C11orf68 (sprot)

A UPF0696 protein C11orf68 that is encoded in the genome of human.


GPT_HUMAN UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase (sprot)

A UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase that is encoded in the genome of human.


Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + dolichyl phosphate = UMP + N-acetyl-D-glucosaminyl-diphosphodolichol.


The chemical reactions and pathways involving UDP-N-acetylglucosamine, a substance composed of N-acetylglucosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate.


TCAL2_HUMAN Transcription elongation factor A protein-like 2 (sprot)

A transcription elongation factor A protein-like 2 that is encoded in the genome of human.


MTRFR_HUMAN Mitochondrial translation release factor in rescue (sprot)

A mitochondrial translation release factor in rescue that is encoded in the genome of human.


GHITM_HUMAN Growth hormone-inducible transmembrane protein (sprot)

A growth hormone-inducible transmembrane protein that is encoded in the genome of human.


BOLA2_HUMAN BolA-like protein 2 (sprot)

A BolA-like protein 2 that is encoded in the genome of human.


MMAD_HUMAN Cobalamin trafficking protein CblD (sprot)

A cobalamin trafficking protein CblD that is encoded in the genome of human.


KCNF1_HUMAN Potassium voltage-gated channel subfamily F member 1 (sprot)

A voltage-gated potassium channel KCNF1 that is encoded in the genome of human.


TXNIP_HUMAN Thioredoxin-interacting protein (sprot)

A thioredoxin-interacting protein that is encoded in the genome of human.


ATX3L_HUMAN Ataxin-3-like protein (sprot)

A protein that is a translation product of the ATXN3L gene in human.


TMX1_HUMAN Thioredoxin-related transmembrane protein 1 (sprot)

A thioredoxin-related transmembrane protein 1 that is encoded in the genome of human.


HRH4_HUMAN Histamine H4 receptor (sprot)

An H4 histamine receptor that is encoded in the genome of human.


NELFA_HUMAN Negative elongation factor A (sprot)

A negative elongation factor A that is encoded in the genome of human.


GCP60_HUMAN Golgi resident protein GCP60 (sprot)

A Golgi resident protein GCP60 that is encoded in the genome of human.


BORG4_HUMAN Cdc42 effector protein 4 (sprot)

A Cdc42 effector protein 4 that is encoded in the genome of human.


G3ST2_HUMAN Galactose-3-O-sulfotransferase 2 (sprot)

A galactose-3-O-sulfotransferase 2 that is encoded in the genome of human.


KDM4C_HUMAN Lysine-specific demethylase 4C (sprot)

A lysine-specific demethylase 4C that is encoded in the genome of human.


NDST4_HUMAN Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 4 (sprot)

A bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 4 that is encoded in the genome of human.


MUC13_HUMAN Mucin-13 (sprot)

A mucin-13 that is encoded in the genome of human.


CENPH_HUMAN Centromere protein H (sprot)

A centromere protein H that is encoded in the genome of human.


SEM4A_HUMAN Semaphorin-4A (sprot)

A semaphorin-4A that is encoded in the genome of human.


TMPS5_HUMAN Transmembrane protease serine 5 (sprot)

A transmembrane protease serine 5 that is encoded in the genome of human.


TPK1_HUMAN Thiamin pyrophosphokinase 1 (sprot)

A thiamin pyrophosphokinase 1 that is encoded in the genome of human.


thiamine diphosphokinase activity

Catalysis of the reaction: ATP + thiamine = AMP + thiamine diphosphate.


thiamine binding

Binding to thiamine (vitamin B1), a water soluble vitamin present in fresh vegetables and meats, especially liver.


PIGM_HUMAN GPI mannosyltransferase 1 (sprot)

A GPI mannosyltransferase 1 that is encoded in the genome of human.


alpha-1,4-mannosyltransferase activity

Catalysis of the transfer of a mannose residue to an oligosaccharide, forming an alpha-(1->4) linkage.


PTN23_HUMAN Tyrosine-protein phosphatase non-receptor type 23 (sprot)

A tyrosine-protein phosphatase non-receptor type 23 that is encoded in the genome of human.


positive regulation of homophilic cell adhesion

Any process that activates or increases the frequency, rate or extent of homophilic cell adhesion.


SEM6B_HUMAN Semaphorin-6B (sprot)

A semaphorin-6B that is encoded in the genome of human.


UN45A_HUMAN Protein unc-45 homolog A (sprot)

A protein unc-45 homolog A that is encoded in the genome of human.


MFSD1_HUMAN Major facilitator superfamily domain-containing protein 1 (sprot)

A major facilitator superfamily domain-containing protein 1 that is encoded in the genome of human.


SMOC2_HUMAN SPARC-related modular calcium-binding protein 2 (sprot)

A SPARC-related modular calcium-binding protein 2 that is encoded in the genome of human.


LRRN3_HUMAN Leucine-rich repeat neuronal protein 3 (sprot)

A leucine-rich repeat neuronal protein 3 that is encoded in the genome of human.


CRSPL_HUMAN Peptidase inhibitor R3HDML (sprot)

A peptidase inhibitor R3HDML that is encoded in the genome of human.


SRMS_HUMAN Tyrosine-protein kinase Srms (sprot)

A tyrosine-protein kinase Srms that is encoded in the genome of human.


PPDPF_HUMAN Pancreatic progenitor cell differentiation and proliferation factor (sprot)

An exocrine differentiation and proliferation factor that is encoded in the genome of human.


DNJC5_HUMAN DnaJ homolog subfamily C member 5 (sprot)

A DnaJ homolog subfamily C member 5 that is encoded in the genome of human.


ABHGB_HUMAN Protein ABHD16B (sprot)

A protein ABHD16B that is encoded in the genome of human.


LIME1_HUMAN Lck-interacting transmembrane adapter 1 (sprot)

An lck-interacting transmembrane adapter 1 that is encoded in the genome of human.


DSN1_HUMAN Kinetochore-associated protein DSN1 homolog (sprot)

A kinetochore-associated protein DSN1 that is encoded in the genome of human.


HIPK3_HUMAN Homeodomain-interacting protein kinase 3 (sprot)

A homeodomain-interacting protein kinase 3 that is encoded in the genome of human.


CA198_HUMAN Uncharacterized protein C1orf198 (sprot)

An uncharacterized protein C1orf198 that is encoded in the genome of human.


RIMS4_HUMAN Regulating synaptic membrane exocytosis protein 4 (sprot)

A regulating synaptic membrane exocytosis protein 4 that is encoded in the genome of human.


KCNKF_HUMAN Potassium channel subfamily K member 15 (sprot)

A potassium channel subfamily K member 15 that is encoded in the genome of human.


CHM4B_HUMAN Charged multivesicular body protein 4b (sprot)

A charged multivesicular body protein 4b that is encoded in the genome of human.


RWDD1_HUMAN RWD domain-containing protein 1 (sprot)

An RWD domain-containing protein 1 that is encoded in the genome of human.


FZD8_HUMAN Frizzled-8 (sprot)

A frizzled-8 that is encoded in the genome of human.


CUED2_HUMAN CUE domain-containing protein 2 (sprot)

A CUE domain-containing protein 2 that is encoded in the genome of human.


FXL15_HUMAN F-box/LRR-repeat protein 15 (sprot)

An F-box/LRR-repeat protein 15 that is encoded in the genome of human.


RBSK_HUMAN Ribokinase (sprot)

A ribokinase that is encoded in the genome of human.


ribokinase activity

Catalysis of the reaction: ATP + D-ribose = ADP + D-ribose 5-phosphate.


D-ribose catabolic process

The chemical reactions and pathways resulting in the breakdown of D-ribose (ribo-pentose).


KCQ1D_HUMAN KCNQ1 downstream neighbor protein (sprot)

A KCNQ1 downstream neighbor protein that is encoded in the genome of human.


A fructosamine-3-kinase that is encoded in the genome of human.


protein-ribulosamine 3-kinase activity

Catalysis of the reaction: ATP + a [protein]-N6-D-ribulosyl-L-lysine <=> ADP + a [protein]-N6-(3-O-phospho-D-ribulosyl)-L-lysine.


protein-fructosamine 3-kinase activity

Catalysis of the reaction: ATP + a [protein]-N6-D-fructosyl-L-lysine <=> ADP + H+ + a [protein]-N6-(3-O-phospho-D-fructosyl)-L-lysine.


fructoselysine metabolic process

The chemical reactions and pathways involving fructoselysine, a fructose molecule containing a lysine group in place of a hydroxyl group.


protein deglycation

The removal of a sugar or dicarbonyl from a glycated protein.


OFUT1_HUMAN GDP-fucose protein O-fucosyltransferase 1 (sprot)

A GDP-fucose protein O-fucosyltransferase 1 that is encoded in the genome of human.


peptide-O-fucosyltransferase activity

Catalysis of the transfer of an alpha-L-fucosyl residue from GDP- beta-L-fucose to the serine hydroxy group of a protein acceptor.


TSY26_HUMAN Putative testis-specific Y-encoded-like protein 3 (sprot)

A putative testis-specific Y-encoded-like protein 3 that is encoded in the genome of human.


PIGU_HUMAN Phosphatidylinositol glycan anchor biosynthesis class U protein (sprot)

A phosphatidylinositol glycan anchor biosynthesis class U protein that is encoded in the genome of human.


MLP3A_HUMAN Microtubule-associated proteins 1A/1B light chain 3A (sprot)

A microtubule-associated proteins 1A/1B light chain 3A that is encoded in the genome of human.


TOR3A_HUMAN Torsin-3A (sprot)

A torsin-3A that is encoded in the genome of human.


WNK1_HUMAN Serine/threonine-protein kinase WNK1 (sprot)

A serine/threonine-protein kinase WNK1 that is encoded in the genome of human.


negative regulation of cell-cell adhesion mediated by integrin

Any process that stops, prevents, or reduces the frequency, rate, or extent of cell-cell adhesion mediated by integrin.


monoatomic cation homeostasis

Any process involved in the maintenance of an internal steady state of monoatomic cations within an organism or cell. Monatomic cations (also called simple cations) are cations consisting of exactly one atom.


positive regulation of termination of RNA polymerase II transcription

Any process that activates or increases the frequency, rate or extent of termination of RNA polymerase II transcription.


AMPB_HUMAN Aminopeptidase B (sprot)

An aminopeptidase B that is encoded in the genome of human.


GLP3L_HUMAN Golgi phosphoprotein 3-like (sprot)

A Golgi phosphoprotein 3-like that is encoded in the genome of human.


GOLP3_HUMAN Golgi phosphoprotein 3 (sprot)

A Golgi phosphoprotein 3 that is encoded in the genome of human.


DPEP2_HUMAN Dipeptidase 2 (sprot)

A dipeptidase 2 that is encoded in the genome of human.


OSGL1_HUMAN tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial (sprot)

A tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial that is encoded in the genome of human.


Catalysis of the reaction: L-threonylcarbamoyladenylate + adenine(37) in tRNA = AMP + N(6)-L-threonylcarbamoyladenine(37) in tRNA.


PLK3_HUMAN Serine/threonine-protein kinase PLK3 (sprot)

A serine/threonine-protein kinase PLK3 that is encoded in the genome of human.


mitotic G1/S transition checkpoint signaling

biolink:Pathway biolink:BiologicalProcess biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:OntologyClass biolink:Occurrent biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

A cell cycle checkpoint that detects and negatively regulates progression from G1 to S phase as part of a mitotic cell cycle.


positive regulation of chaperone-mediated autophagy

Any process that activates or increases the frequency, rate or extent of chaperone-mediated autophagy.


positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia

Any positive regulation of proteasomal ubiquitin-dependent protein catabolic process that is involved in a cellular response to hypoxia.


SAV1_HUMAN Protein salvador homolog 1 (sprot)

A protein salvador homolog 1 that is encoded in the genome of human.


keratinocyte apoptotic process

Any apoptotic process in a keratinocyte. A keratinocyte is an epidermal cell which synthesizes keratin and undergoes a characteristic change as it moves upward from the basal layers of the epidermis to the cornified (horny) layer of the skin.


TBB1_HUMAN Tubulin beta-1 chain (sprot)

A tubulin beta-1 chain that is encoded in the genome of human.


DPEP3_HUMAN Dipeptidase 3 (sprot)

A dipeptidase 3 that is encoded in the genome of human.


CSTN2_HUMAN Calsyntenin-2 (sprot)

A calsyntenin-2 that is encoded in the genome of human.


NXF3_HUMAN Nuclear RNA export factor 3 (sprot)

A nuclear RNA export factor 3 that is encoded in the genome of human.


RHOJ_HUMAN Rho-related GTP-binding protein RhoJ (sprot)

A Rho-related GTP-binding protein RhoJ that is encoded in the genome of human.


DEFI6_HUMAN Differentially expressed in FDCP 6 homolog (sprot)

A differentially expressed in FDCP 6 that is encoded in the genome of human.


An alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3-N-acetyl-galactosaminide alpha-2,6-sialyltransferase that is encoded in the genome of human.


SMOC1_HUMAN SPARC-related modular calcium-binding protein 1 (sprot)

A SPARC-related modular calcium-binding protein 1 that is encoded in the genome of human.


E41L1_HUMAN Band 4.1-like protein 1 (sprot)

A band 4.1-like protein 1 that is encoded in the genome of human.


CST9L_HUMAN Cystatin-9-like (sprot)

A cystatin-9-like that is encoded in the genome of human.


GAPR1_HUMAN Golgi-associated plant pathogenesis-related protein 1 (sprot)

A Golgi-associated plant pathogenesis-related protein 1 that is encoded in the genome of human.


DPH3B_HUMAN Putative DPH3 homolog B (sprot)


FA83D_HUMAN Protein FAM83D (sprot)

A protein FAM83D that is encoded in the genome of human.


protein localization to mitotic spindle

A process in which a protein is transported to, or maintained in, a location within a mitotic spindle.


RD21L_HUMAN Double-strand-break repair protein rad21-like protein 1 (sprot)

A double-strand-break repair protein rad21-like protein 1 that is encoded in the genome of human.


ZHX3_HUMAN Zinc fingers and homeoboxes protein 3 (sprot)

A zinc fingers and homeoboxes protein 3 that is encoded in the genome of human.


SEHL2_HUMAN Serine hydrolase-like protein 2 (sprot)

A serine hydrolase-like protein 2 that is encoded in the genome of human.


EMRE_HUMAN Essential MCU regulator, mitochondrial (sprot)

An essential MCU regulator, mitochondrial that is encoded in the genome of human.


RIBC2_HUMAN RIB43A-like with coiled-coils protein 2 (sprot)

A RIB43A-like with coiled-coils protein 2 that is encoded in the genome of human.


MTG2_HUMAN Mitochondrial ribosome-associated GTPase 2 (sprot)

A mitochondrial ribosome-associated GTPase 2 that is encoded in the genome of human.


SENP3_HUMAN Sentrin-specific protease 3 (sprot)

A sentrin-specific protease 3 that is encoded in the genome of human.


OSBL3_HUMAN Oxysterol-binding protein-related protein 3 (sprot)

An oxysterol-binding protein-related protein 3 that is encoded in the genome of human.


SMRCD_HUMAN SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 (sprot)

A SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 that is encoded in the genome of human.


FBX44_HUMAN F-box only protein 44 (sprot)

An F-box only protein 44 that is encoded in the genome of human.


PKHA4_HUMAN Pleckstrin homology domain-containing family A member 4 (sprot)

A pleckstrin homology domain-containing family A member 4 that is encoded in the genome of human.


EHD1_HUMAN EH domain-containing protein 1 (sprot)

An EH domain-containing protein 1 that is encoded in the genome of human.


RNF41_HUMAN E3 ubiquitin-protein ligase NRDP1 (sprot)

An E3 ubiquitin-protein ligase NRDP1 that is encoded in the genome of human.


PRD13_HUMAN PR domain zinc finger protein 13 (sprot)

A PR domain zinc finger protein 13 that is encoded in the genome of human.


PRD12_HUMAN PR domain zinc finger protein 12 (sprot)

A PR domain zinc finger protein 12 that is encoded in the genome of human.


GSX1_HUMAN GS homeobox 1 (sprot)

A GS homeobox 1 that is encoded in the genome of human.


ZSC16_HUMAN Zinc finger and SCAN domain-containing protein 16 (sprot)

A zinc finger and SCAN domain-containing protein 16 that is encoded in the genome of human.


COE3_HUMAN Transcription factor COE3 (sprot)

A transcription factor COE3 that is encoded in the genome of human.


RGCC_HUMAN Regulator of cell cycle RGCC (sprot)

A response gene to complement 32 protein that is encoded in the genome of human.


negative regulation of exit from mitosis

Any process involved in the inhibition of progression from anaphase/telophase (high mitotic CDK activity) to G1 (low mitotic CDK activity).


GSTO2_HUMAN Glutathione S-transferase omega-2 (sprot)

A glutathione S-transferase omega-2 that is encoded in the genome of human.


ZN335_HUMAN Zinc finger protein 335 (sprot)

A zinc finger protein 335 that is encoded in the genome of human.


CAPAM_HUMAN mRNA (2'-O-methyladenosine-N(6)-)-methyltransferase (sprot)

An mRNA (2'-O-methyladenosine-N(6)-)-methyltransferase that is encoded in the genome of human.


ESF1_HUMAN ESF1 homolog (sprot)

An ESF1 that is encoded in the genome of human.


BAFL_HUMAN Barrier-to-autointegration factor-like protein (sprot)

A barrier-to-autointegration factor-like protein that is encoded in the genome of human.


KLH31_HUMAN Kelch-like protein 31 (sprot)

A kelch-like protein 31 that is encoded in the genome of human.


ALG2_HUMAN Alpha-1,3/1,6-mannosyltransferase ALG2 (sprot)

An alpha-1,3/1,6-mannosyltransferase ALG2 that is encoded in the genome of human.


Catalysis of the reaction: beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + GDP-alpha-D-mannose = alpha-D-Man-(1->3)-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + GDP + H+. This reaction is the transfer of an alpha-D-mannosyl residue from GDP-mannose into lipid-linked oligosaccharide, forming an alpha-(1->3)-D-mannosyl-D-mannose linkage.


Catalysis of the reaction: GDP-alpha-D-mannose(2-) + a (mannosyl)2-(N-acetylglucosaminyl)2-diphosphodolichol <=> H+ + GDP(3-) + a (mannosyl)3-(N-acetylglucosaminyl)2-diphosphodolichol.


ACTL8_HUMAN Actin-like protein 8 (sprot)

An actin-like protein 8 that is encoded in the genome of human.


ZN644_HUMAN Zinc finger protein 644 (sprot)

A zinc finger protein 644 that is encoded in the genome of human.


HEAT1_HUMAN HEAT repeat-containing protein 1 (sprot)

A HEAT repeat-containing protein 1 that is encoded in the genome of human.


DUS21_HUMAN Dual specificity protein phosphatase 21 (sprot)

A dual specificity protein phosphatase 21 that is encoded in the genome of human.


VIAAT_HUMAN Vesicular inhibitory amino acid transporter (sprot)

A vesicular inhibitory amino acid transporter that is encoded in the genome of human.


gamma-aminobutyric acid:proton symporter activity

Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: gamma-aminobutyric acid(out) + H+(out) = gamma-aminobutyric acid(in) + H+(in).


Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glycine(out) + H+(in) = glycine(in) + H+(out).


gamma-aminobutyric acid:proton antiporter activity

Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: 4-aminobutanoate(out) + H+(in) = 4-aminobutanoate(in) + H+(out).


beta-alanine transport

The directed movement of beta-alanine, 3-aminopropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


cone cell pedicle

A specialized axon terminus which is produced by retinal cone cells. Pedicles are large, conical, flat end-feet (8-10 micrometers diameter) of the retinal cone axon that lie more or less side by side on the same plane at the outer edge of the outer plexiform layer (OPL).


CFA68_HUMAN Cilia- and flagella-associated protein 68 (sprot)

A UPF0686 protein C11orf1 that is encoded in the genome of human.


ZN768_HUMAN Zinc finger protein 768 (sprot)

A zinc finger protein 768 that is encoded in the genome of human.


SUV92_HUMAN Histone-lysine N-methyltransferase SUV39H2 (sprot)

A histone-lysine N-methyltransferase SUV39H2 that is encoded in the genome of human.


PIEZ2_HUMAN Piezo-type mechanosensitive ion channel component 2 (sprot)

A piezo-type mechanosensitive ion channel component 2 that is encoded in the genome of human.


ZBTB3_HUMAN Zinc finger and BTB domain-containing protein 3 (sprot)

A zinc finger and BTB domain-containing protein 3 that is encoded in the genome of human.


ELOV6_HUMAN Elongation of very long chain fatty acids protein 6 (sprot)

An elongation of very long chain fatty acids protein 6 that is encoded in the genome of human.


TAF1D_HUMAN TATA box-binding protein-associated factor RNA polymerase I subunit D (sprot)

A TATA box-binding protein-associated factor RNA polymerase I subunit D that is encoded in the genome of human.


SG196_HUMAN Protein O-mannose kinase (sprot)

A protein O-mannose kinase that is encoded in the genome of human.


carbohydrate kinase activity

Catalysis of the transfer of a phosphate group, usually from ATP, to a carbohydrate substrate molecule.


THAP9_HUMAN DNA transposase THAP9 (sprot)

A DNA transposase THAP9 that is encoded in the genome of human.


DNA transposition

A type of transposition in which a transposable element (transposon) is moved to another part of a genome, either by a cut-and-paste mechanism or a replicative mechanism.


RABE2_HUMAN Rab GTPase-binding effector protein 2 (sprot)

A Rab GTPase-binding effector protein 2 that is encoded in the genome of human.


PDZD7_HUMAN PDZ domain-containing protein 7 (sprot)

A PDZ domain-containing protein 7 that is encoded in the genome of human.


TFB2M_HUMAN Dimethyladenosine transferase 2, mitochondrial (sprot)

A dimethyladenosine transferase 2, mitochondrial that is encoded in the genome of human.


ZCHC4_HUMAN rRNA N6-adenosine-methyltransferase ZCCHC4 (sprot)

An rRNA N6-adenosine-methyltransferase ZCCHC4 that is encoded in the genome of human.


Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N6-methyladenine.


IKZF5_HUMAN Zinc finger protein Pegasus (sprot)

A zinc finger protein Pegasus that is encoded in the genome of human.


CDCP1_HUMAN CUB domain-containing protein 1 (sprot)

A CUB domain-containing protein 1 that is encoded in the genome of human.


STEEP_HUMAN STING ER exit protein (sprot)

A STING ER exit protein that is encoded in the genome of human.


CIA2A_HUMAN Cytosolic iron-sulfur assembly component 2A (sprot)

A cytosolic iron-sulfur assembly component 2A that is encoded in the genome of human.


SLIK6_HUMAN SLIT and NTRK-like protein 6 (sprot)

A SLIT and NTRK-like protein 6 that is encoded in the genome of human.


linear vestibuloocular reflex

A vestibular reflex by which a response to a linear acceleration stimulus begins with an afferent nerve impulse from a receptor in the otolith and ends with the compensatory action of eye muscles. Signaling never reaches a level of consciousness.


DHX35_HUMAN Probable ATP-dependent RNA helicase DHX35 (sprot)

A probable ATP-dependent RNA helicase DHX35 that is encoded in the genome of human.


F124B_HUMAN Protein FAM124B (sprot)

A protein FAM124B that is encoded in the genome of human.


ZN576_HUMAN Zinc finger protein 576 (sprot)

A zinc finger protein 576 that is encoded in the genome of human.


PIF1_HUMAN ATP-dependent DNA helicase PIF1 (sprot)

An ATP-dependent DNA helicase PIF1 that is encoded in the genome of human.


5'-3' DNA/RNA helicase activity

Unwinding of a DNA/RNA duplex in the 5' to 3' direction, driven by ATP hydrolysis.


RERGL_HUMAN Ras-related and estrogen-regulated growth inhibitor-like protein (sprot)

A Ras-related and estrogen-regulated growth inhibitor-like protein that is encoded in the genome of human.


RPP21_HUMAN Ribonuclease P protein subunit p21 (sprot)

A ribonuclease P protein subunit p21 that is encoded in the genome of human.


NSUN3_HUMAN tRNA (cytosine(34)-C(5))-methyltransferase, mitochondrial (sprot)

A tRNA (cytosine(34)-C(5))-methyltransferase, mitochondrial that is encoded in the genome of human.


tRNA wobble base cytosine methylation

The process in which the base of cytosine at position 34 in the anticodon of a tRNA is post-transcriptionally methylated at the C5 position.


IGFR1_HUMAN IGF-like family receptor 1 (sprot)

An IGF-like family receptor 1 that is encoded in the genome of human.


STN1_HUMAN CST complex subunit STN1 (sprot)

An oligonucleotide/oligosaccharide-binding fold-containing protein 1 that is encoded in the genome of human.


ASB7_HUMAN Ankyrin repeat and SOCS box protein 7 (sprot)

An ankyrin repeat and SOCS box protein 7 that is encoded in the genome of human.


BICC1_HUMAN Protein bicaudal C homolog 1 (sprot)

A protein bicaudal C homolog 1 that is encoded in the genome of human.


DEN2D_HUMAN DENN domain-containing protein 2D (sprot)

A DENN domain-containing protein 2D that is encoded in the genome of human.


PCX3_HUMAN Pecanex-like protein 3 (sprot)

A pecanex-like protein 3 that is encoded in the genome of human.


Z385D_HUMAN Zinc finger protein 385D (sprot)

A zinc finger protein 385D that is encoded in the genome of human.


CLMP_HUMAN CXADR-like membrane protein (sprot)

An adipocyte adhesion molecule that is encoded in the genome of human.


EPHX3_HUMAN Epoxide hydrolase 3 (sprot)

An epoxide hydrolase 3 that is encoded in the genome of human.


XKR8_HUMAN XK-related protein 8 (sprot)

An XK-related protein 8 that is encoded in the genome of human.


HAUS4_HUMAN HAUS augmin-like complex subunit 4 (sprot)

A HAUS augmin-like complex subunit 4 that is encoded in the genome of human.


FNDC4_HUMAN Fibronectin type III domain-containing protein 4 (sprot)

A fibronectin type III domain-containing protein 4 that is encoded in the genome of human.


CC134_HUMAN Coiled-coil domain-containing protein 134 (sprot)

A coiled-coil domain-containing protein 134 that is encoded in the genome of human.


STPAP_HUMAN Speckle targeted PIP5K1A-regulated poly(A) polymerase (sprot)

A speckle targeted PIP5K1A-regulated poly(A) polymerase that is encoded in the genome of human.


TM38A_HUMAN Trimeric intracellular cation channel type A (sprot)

A trimeric intracellular cation channel type A that is encoded in the genome of human.


CCD86_HUMAN Coiled-coil domain-containing protein 86 (sprot)

A coiled-coil domain-containing protein 86 that is encoded in the genome of human.


REEP4_HUMAN Receptor expression-enhancing protein 4 (sprot)

A receptor expression-enhancing protein 4 that is encoded in the genome of human.


SOX17_HUMAN Transcription factor SOX-17 (sprot)

A transcription factor SOX-17 that is encoded in the genome of human.


cardiogenic plate morphogenesis

The process in which the anatomical structures of the cardiogenic plate are generated and organized. The cardiogenic plate is the first recognizable structure derived from the heart field.


regulation of cardiac cell fate specification

Any process that modulates the frequency, rate or extent of cardiac cell fate specification.


CSTP1_HUMAN Centriolar satellite-associated tubulin polyglutamylase complex regulator 1 (sprot)

A centriolar satellite-associated tubulin polyglutamylase complex regulator 1 that is encoded in the genome of human.


ILRUN_HUMAN Protein ILRUN (sprot)

A protein ILRUN that is encoded in the genome of human.


OPA3_HUMAN Optic atrophy 3 protein (sprot)

An optic atrophy 3 protein that is encoded in the genome of human.


TM231_HUMAN Transmembrane protein 231 (sprot)

A transmembrane protein 231 that is encoded in the genome of human.


ARMC7_HUMAN Armadillo repeat-containing protein 7 (sprot)

An armadillo repeat-containing protein 7 that is encoded in the genome of human.


RETR1_HUMAN Reticulophagy regulator 1 (sprot)

A reticulophagy regulator 1 that is encoded in the genome of human.


TASP1_HUMAN Threonine aspartase 1 (sprot)

A threonine aspartase 1 that is encoded in the genome of human.


SLAP2_HUMAN Src-like-adapter 2 (sprot)

A Src-like-adapter 2 that is encoded in the genome of human.


CIAO3_HUMAN Cytosolic iron-sulfur assembly component 3 (sprot)

A cytosolic iron-sulfur assembly component 3 that is encoded in the genome of human.


DHX33_HUMAN ATP-dependent RNA helicase DHX33 (sprot)

An ATP-dependent RNA helicase DHX33 that is encoded in the genome of human.


ACSS3_HUMAN Acyl-CoA synthetase short-chain family member 3, mitochondrial (sprot)

An acyl-CoA synthetase short-chain family member 3, mitochondrial that is encoded in the genome of human.


NOL6_HUMAN Nucleolar protein 6 (sprot)

A nucleolar protein 6 that is encoded in the genome of human.


ZDHC6_HUMAN Palmitoyltransferase ZDHHC6 (sprot)

A palmitoyltransferase ZDHHC6 that is encoded in the genome of human.


protein stearoylation

The covalent attachment of a stearoyl group to an amino acid in a protein.


WDCP_HUMAN WD repeat and coiled-coil-containing protein (sprot)

A WD repeat and coiled-coil-containing protein that is encoded in the genome of human.


YTDC2_HUMAN 3'-5' RNA helicase YTHDC2 (sprot)

A 3'-5' RNA helicase YTHDC2 that is encoded in the genome of human.


AZI2_HUMAN 5-azacytidine-induced protein 2 (sprot)

A 5-azacytidine-induced protein 2 that is encoded in the genome of human.


ES8L2_HUMAN Epidermal growth factor receptor kinase substrate 8-like protein 2 (sprot)

An epidermal growth factor receptor kinase substrate 8-like protein 2 that is encoded in the genome of human.


ESRP2_HUMAN Epithelial splicing regulatory protein 2 (sprot)

An epithelial splicing regulatory protein 2 that is encoded in the genome of human.


RPAP3_HUMAN RNA polymerase II-associated protein 3 (sprot)

An RNA polymerase II-associated protein 3 that is encoded in the genome of human.


R2TP complex

A highly conserved protein complex comprised of two ATP-dependent DNA helicases (Rvb1p and Rvb2p in yeast, Pontin52 and Reptin52 in humans), Pih1p in yeast or PIH1D1 in humans, and Tah1 in yeast or RPAP3 in humans. The complex associates with Hsp90 and is thought to have a role in assembly of large protein or protein/nucleic acid complexes. In this role it is involved in multiple processes such as box C/D snoRNP biogenesis, phosphatidylinositol-3 kinase-related protein kinase (PIKK) signaling, RNA polymerase II assembly, and others.


BCAS3_HUMAN BCAS3 microtubule associated cell migration factor (sprot)

A BCAS3 microtubule associated cell migration factor that is encoded in the genome of human.


ALG9_HUMAN Alpha-1,2-mannosyltransferase ALG9 (sprot)

An alpha-1,2-mannosyltransferase ALG9 that is encoded in the genome of human.


Catalysis of the reaction: alpha-D-man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-(alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-(alpha-D-Man-(1->6))-alpha-D-Man-(1->6))-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + dolichyl D-mannosyl phosphate = H+ + alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-(alpha-D-Man-(1->2)-alpha-D-Man-(1->6))-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + dolichyl phosphate.


Catalysis of the reaction: alpha-D-man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-(alpha-D-Man-(1->3)-alpha-D-Man-(1->6))-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + dolichyl D-mannosyl phosphate = H+ + alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-(alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-alpha-D-Man-(1->6))-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + dolichyl phosphate.


LDAH_HUMAN Lipid droplet-associated hydrolase (sprot)

A lipid droplet-associated hydrolase that is encoded in the genome of human.


RIOX1_HUMAN Ribosomal oxygenase 1 (sprot)

A ribosomal oxygenase 1 that is encoded in the genome of human.


ANTR1_HUMAN Anthrax toxin receptor 1 (sprot)

An anthrax toxin receptor 1 that is encoded in the genome of human.


TM134_HUMAN Transmembrane protein 134 (sprot)

A transmembrane protein 134 that is encoded in the genome of human.


CS044_HUMAN Uncharacterized protein C19orf44 (sprot)

An uncharacterized protein C19orf44 that is encoded in the genome of human.


WDR55_HUMAN WD repeat-containing protein 55 (sprot)

A WD repeat-containing protein 55 that is encoded in the genome of human.


RN167_HUMAN E3 ubiquitin-protein ligase RNF167 (sprot)

An E3 ubiquitin-protein ligase RNF167 that is encoded in the genome of human.


RANB3_HUMAN Ran-binding protein 3 (sprot)

A Ran-binding protein 3 that is encoded in the genome of human.


EGLN3_HUMAN Prolyl hydroxylase EGLN3 (sprot)

A prolyl hydroxylase EGLN3 that is encoded in the genome of human.


GARE1_HUMAN GRB2-associated and regulator of MAPK protein 1 (sprot)

A GRB2-associated and regulator of MAPK protein 1 that is encoded in the genome of human.


ZN552_HUMAN Zinc finger protein 552 (sprot)

A zinc finger protein 552 that is encoded in the genome of human.


PACER_HUMAN Protein associated with UVRAG as autophagy enhancer (sprot)

A protein associated with UVRAG as autophagy enhancer that is encoded in the genome of human.


autophagosome-endosome fusion

The process in which an autophagosome fuses with an endosome to create an intermediate autophagic organelle called amphisome.


PG2IP_HUMAN PGAP2-interacting protein (sprot)

A PGAP2-interacting protein that is encoded in the genome of human.


SPRNG_HUMAN SREBP regulating gene protein (sprot)

An SREBP regulating gene protein that is encoded in the genome of human.


LRC19_HUMAN Leucine-rich repeat-containing protein 19 (sprot)

A leucine-rich repeat-containing protein 19 that is encoded in the genome of human.


ASB8_HUMAN Ankyrin repeat and SOCS box protein 8 (sprot)

An ankyrin repeat and SOCS box protein 8 that is encoded in the genome of human.


GREM2_HUMAN Gremlin-2 (sprot)

A gremlin-2 that is encoded in the genome of human.


regulation of cytokine activity

Any process that modulates the rate, frequency or extent of the activity of a molecule that controls the survival, growth, differentiation and effector function of tissues and cells.


DCTP1_HUMAN dCTP pyrophosphatase 1 (sprot)

A dCTP pyrophosphatase 1 that is encoded in the genome of human.


pyrimidine deoxyribonucleotide binding

Binding to a pyrimidine deoxyribonucleotide, any compound consisting of a pyrimidine deoxyribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the deoxyribose moiety.


dCTP diphosphatase activity

Catalysis of the reaction: dCTP + H2O = dCMP + H+ + diphosphate.


dCTP catabolic process

The chemical reactions and pathways resulting in the breakdown of dCTP, deoxycytidine triphosphate.


RNZ1_HUMAN Zinc phosphodiesterase ELAC protein 1 (sprot)

A zinc phosphodiesterase ELAC protein 1 that is encoded in the genome of human.


SH24A_HUMAN SH2 domain-containing protein 4A (sprot)

An SH2 domain-containing protein 4A that is encoded in the genome of human.


EXO5_HUMAN Exonuclease V (sprot)

An exonuclease V that is encoded in the genome of human.


PEAK1_HUMAN Inactive tyrosine-protein kinase PEAK1 (sprot)

An inactive tyrosine-protein kinase PEAK1 that is encoded in the genome of human.


CPLN1_HUMAN Ciliogenesis and planar polarity effector 1 (sprot)

A ciliogenesis and planar polarity effector 1 that is encoded in the genome of human.


RPF2_HUMAN Ribosome production factor 2 homolog (sprot)

A ribosome production factor 2 homolog that is encoded in the genome of human.


SMYD3_HUMAN Histone-lysine N-methyltransferase SMYD3 (sprot)

A histone-lysine N-methyltransferase SMYD3 that is encoded in the genome of human.


CG069_HUMAN Putative uncharacterized protein PKD1L1-AS1 (sprot)


SYNCI_HUMAN Syncoilin (sprot)

A syncoilin that is encoded in the genome of human.


AAMDC_HUMAN Mth938 domain-containing protein (sprot)

An Mth938 domain-containing protein that is encoded in the genome of human.


DOCK5_HUMAN Dedicator of cytokinesis protein 5 (sprot)

A dedicator of cytokinesis protein 5 that is encoded in the genome of human.


WDR26_HUMAN WD repeat-containing protein 26 (sprot)

A WD repeat-containing protein 26 that is encoded in the genome of human.


TDRD3_HUMAN Tudor domain-containing protein 3 (sprot)

A tudor domain-containing protein 3 that is encoded in the genome of human.


CH033_HUMAN UPF0488 protein C8orf33 (sprot)

A UPF0488 protein C8orf33 that is encoded in the genome of human.


AT133_HUMAN Polyamine-transporting ATPase 13A3 (sprot)

A polyamine-transporting ATPase 13A3 that is encoded in the genome of human.


ABC-type putrescine transporter activity

Catalysis of the reaction: ATP + H2O + putrescine(out) -> ADP + phosphate + putrescine(in).


P-type transmembrane transporter activity

Primary active transporter that auto-phosphorylates (hence P) at a key conserved aspartate residue, generating a conformational change that allows transport of the substrate. Hydrolysis of the phosphorylated Asp residue, catalyzed by the actuator (A) domain, results in another state with occluded substrates. Upon dissociation of Mg2+ and inorganic phosphate (Pi), the enzyme reverts to the initial state, in which the counter-transported substrate is released into the cytosol.


T185B_HUMAN Transmembrane protein 185B (sprot)

A transmembrane protein 185B that is encoded in the genome of human.


MET17_HUMAN Methyltransferase-like protein 17, mitochondrial (sprot)

A protein RSM22, mitochondrial that is encoded in the genome of human.


PPR3E_HUMAN Protein phosphatase 1 regulatory subunit 3E (sprot)

A protein phosphatase 1 regulatory subunit 3E that is encoded in the genome of human.


KI3X1_HUMAN Putative killer cell immunoglobulin-like receptor-like protein KIR3DX1 (sprot)


SDS3_HUMAN Sin3 histone deacetylase corepressor complex component SDS3 (sprot)

A Sin3 histone deacetylase corepressor complex component SDS3 that is encoded in the genome of human.


ZSWM4_HUMAN Zinc finger SWIM domain-containing protein 4 (sprot)

A zinc finger SWIM domain-containing protein 4 that is encoded in the genome of human.


VISTA_HUMAN V-type immunoglobulin domain-containing suppressor of T-cell activation (sprot)

A V-type immunoglobulin domain-containing suppressor of T-cell activation that is encoded in the genome of human.


positive regulation of collagen catabolic process

Any process that activates or increases the frequency, rate or extent of collagen catabolism. Collagen catabolism is the proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix.


SFR19_HUMAN Splicing factor, arginine/serine-rich 19 (sprot)

A splicing factor, arginine/serine-rich 19 that is encoded in the genome of human.


MB12B_HUMAN Multivesicular body subunit 12B (sprot)

A multivesicular body subunit 12B that is encoded in the genome of human.


PKHG2_HUMAN Pleckstrin homology domain-containing family G member 2 (sprot)

A pleckstrin homology domain-containing family G member 2 that is encoded in the genome of human.


ZN442_HUMAN Zinc finger protein 442 (sprot)

A zinc finger protein 442 that is encoded in the genome of human.


ZN665_HUMAN Zinc finger protein 665 (sprot)

A zinc finger protein 665 that is encoded in the genome of human.


ZN703_HUMAN Zinc finger protein 703 (sprot)

A zinc finger protein 703 that is encoded in the genome of human.


CTSRB_HUMAN Cation channel sperm-associated auxiliary subunit beta (sprot)

A cation channel sperm-associated auxiliary subunit beta that is encoded in the genome of human.


CJ095_HUMAN Uncharacterized protein C10orf95 (sprot)

A protein that is a translation product of the C10orf95 gene in human.


AUNIP_HUMAN Aurora kinase A- and ninein-interacting protein (sprot)

An aurora kinase A and ninein-interacting protein that is encoded in the genome of human.


CCSE2_HUMAN Serine-rich coiled-coil domain-containing protein 2 (sprot)

A serine-rich coiled-coil domain-containing protein 2 that is encoded in the genome of human.


SYNG1_HUMAN Synapse differentiation-inducing gene protein 1 (sprot)

A synapse differentiation-inducing gene protein 1 that is encoded in the genome of human.


NAA60_HUMAN N-alpha-acetyltransferase 60 (sprot)

An N-alpha-acetyltransferase 60 that is encoded in the genome of human.


The acetylation of the N-terminal methionine of proteins to form the derivative N-acetyl-L-methionine.


RDD1_HUMAN Required for drug-induced death protein 1 (sprot)

A required for drug-induced death protein 1 that is encoded in the genome of human.


ZN696_HUMAN Zinc finger protein 696 (sprot)

A zinc finger protein 696 that is encoded in the genome of human.


IFT22_HUMAN Intraflagellar transport protein 22 homolog (sprot)

An intraflagellar transport protein 22 that is encoded in the genome of human.


DIK2B_HUMAN Divergent protein kinase domain 2B (sprot)

A divergent protein kinase domain 2B that is encoded in the genome of human.


NRDE2_HUMAN Nuclear exosome regulator NRDE2 (sprot)

A nuclear exosome regulator NRDE2 that is encoded in the genome of human.


KAT8_HUMAN Histone acetyltransferase KAT8 (sprot)

A histone acetyltransferase KAT8 that is encoded in the genome of human.


PGES2_HUMAN Prostaglandin E synthase 2 (sprot)

A prostaglandin E synthase 2 that is encoded in the genome of human.


TLE6_HUMAN Transducin-like enhancer protein 6 (sprot)

A transducin-like enhancer protein 6 that is encoded in the genome of human.


PACC1_HUMAN Proton-activated chloride channel (sprot)

A proton-activated chloride channel that is encoded in the genome of human.


pH-gated chloride channel activity

A gated channel activity that enables the transmembrane transfer of a chloride ion by a channel that opens in response to a change in pH.


PHAX_HUMAN Phosphorylated adapter RNA export protein (sprot)

A phosphorylated adapter RNA export protein that is encoded in the genome of human.


DCR1B_HUMAN 5' exonuclease Apollo (sprot)

A 5' exonuclease Apollo that is encoded in the genome of human.


DJC18_HUMAN DnaJ homolog subfamily C member 18 (sprot)

A DnaJ homolog subfamily C member 18 that is encoded in the genome of human.


METL8_HUMAN tRNA N(3)-methylcytidine methyltransferase METTL8, mitochondrial (sprot)

A tRNA N(3)-methylcytidine methyltransferase METTL8, mitochondrial that is encoded in the genome of human.


mRNA methyltransferase activity

Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a nucleoside residue in an mRNA molecule.


UBE2Z_HUMAN Ubiquitin-conjugating enzyme E2 Z (sprot)

A ubiquitin-conjugating enzyme E2 Z that is encoded in the genome of human.


GEMI7_HUMAN Gem-associated protein 7 (sprot)

A gem-associated protein 7 that is encoded in the genome of human.


NPAL2_HUMAN NIPA-like protein 2 (sprot)

A NIPA-like protein 2 that is encoded in the genome of human.


ACAD9_HUMAN Complex I assembly factor ACAD9, mitochondrial (sprot)

A complex I assembly factor ACAD9, mitochondrial that is encoded in the genome of human.


TBA4B_HUMAN Putative tubulin-like protein alpha-4B (sprot)

A protein that is a translation product of the TUBA4B gene in human.


NT5D2_HUMAN 5'-nucleotidase domain-containing protein 2 (sprot)

A 5'-nucleotidase domain-containing protein 2 that is encoded in the genome of human.


MT21D_HUMAN Protein N-lysine methyltransferase METTL21D (sprot)

A protein N-lysine methyltransferase METTL21D that is encoded in the genome of human.


YYAP1_HUMAN YY1-associated protein 1 (sprot)

A YY1-associated protein 1 that is encoded in the genome of human.


RMD5A_HUMAN E3 ubiquitin-protein transferase RMND5A (sprot)

An E3 ubiquitin-protein transferase RMND5A that is encoded in the genome of human.


PKRI1_HUMAN PRKR-interacting protein 1 (sprot)

A PRKR-interacting protein 1 that is encoded in the genome of human.


TTC12_HUMAN Tetratricopeptide repeat protein 12 (sprot)

A tetratricopeptide repeat protein 12 that is encoded in the genome of human.


ZMAT4_HUMAN Zinc finger matrin-type protein 4 (sprot)

A zinc finger matrin-type protein 4 that is encoded in the genome of human.


CSR2B_HUMAN Cysteine-rich protein 2-binding protein (sprot)

A cysteine-rich protein 2-binding protein that is encoded in the genome of human.


ZN430_HUMAN Zinc finger protein 430 (sprot)

A zinc finger protein 430 that is encoded in the genome of human.


CAAP1_HUMAN Caspase activity and apoptosis inhibitor 1 (sprot)

A caspase activity and apoptosis inhibitor 1 that is encoded in the genome of human.


NOL11_HUMAN Nucleolar protein 11 (sprot)

A nucleolar protein 11 that is encoded in the genome of human.


DDX31_HUMAN Probable ATP-dependent RNA helicase DDX31 (sprot)

A probable ATP-dependent RNA helicase DDX31 that is encoded in the genome of human.


TMT1A_HUMAN N6-adenosine-methyltransferase TMT1A (sprot)

A putative methyltransferase-like protein 7A that is encoded in the genome of human.


MANS1_HUMAN MANSC domain-containing protein 1 (sprot)

A MANSC domain-containing protein 1 that is encoded in the genome of human.


PAAT_HUMAN ATPase PAAT (sprot)

An ATPase PAAT that is encoded in the genome of human.


MMRN2_HUMAN Multimerin-2 (sprot)

A multimerin-2 that is encoded in the genome of human.


CQ10B_HUMAN Coenzyme Q-binding protein COQ10 homolog B, mitochondrial (sprot)

A coenzyme Q-binding protein COQ10 homolog B, mitochondrial that is encoded in the genome of human.


BRD9_HUMAN Bromodomain-containing protein 9 (sprot)

A bromodomain-containing protein 9 that is encoded in the genome of human.


CNNM2_HUMAN Metal transporter CNNM2 (sprot)

A metal transporter CNNM2 that is encoded in the genome of human.


MINY3_HUMAN Ubiquitin carboxyl-terminal hydrolase MINDY-3 (sprot)

A ubiquitin carboxyl-terminal hydrolase MINDY-3 that is encoded in the genome of human.


EVA1A_HUMAN Protein eva-1 homolog A (sprot)

A protein eva-1 homolog A that is encoded in the genome of human.


ZN395_HUMAN Zinc finger protein 395 (sprot)

A zinc finger protein 395 that is encoded in the genome of human.


PORED_HUMAN Polyprenol reductase (sprot)

A polyprenol reductase that is encoded in the genome of human.


polyprenol reductase activity

Catalysis of the reaction: NADP + a ditrans,polycis-dolichol = NADPH + H+ + a di-trans, poly-cis-polyprenol.


polyprenol catabolic process

The chemical reactions and pathways resulting in the breakdown of polyprenols, prenols with more than 4 isoprenoid residues, which may be all-trans, or a mixture of cis and trans.


CCNP_HUMAN Cyclin-P (sprot)

A cyclin-P that is encoded in the genome of human.


MOB1A_HUMAN MOB kinase activator 1A (sprot)

A MOB kinase activator 1A that is encoded in the genome of human.


AKTIP_HUMAN AKT-interacting protein (sprot)

An AKT-interacting protein that is encoded in the genome of human.


ZFAN3_HUMAN AN1-type zinc finger protein 3 (sprot)

An AN1-type zinc finger protein 3 that is encoded in the genome of human.


ECT2_HUMAN Protein ECT2 (sprot)

A protein ECT2 that is encoded in the genome of human.


regulation of cytokinesis, actomyosin contractile ring assembly

Any process that modulates the frequency, rate or extent of cytokinesis, actomyosin contractile ring assembly.


F204A_HUMAN Protein FAM204A (sprot)

A protein FAM204A that is encoded in the genome of human.


PKHF2_HUMAN Pleckstrin homology domain-containing family F member 2 (sprot)

A pleckstrin homology domain-containing family F member 2 that is encoded in the genome of human.


TRI45_HUMAN E3 ubiquitin-protein ligase TRIM45 (sprot)

A tripartite motif-containing protein 45 that is encoded in the genome of human.


IPPK_HUMAN Inositol-pentakisphosphate 2-kinase (sprot)

An inositol-pentakisphosphate 2-kinase that is encoded in the genome of human.


inositol pentakisphosphate 2-kinase activity

Catalysis of the reaction: 1D-myo-inositol 1,3,4,5,6-pentakisphosphate + ATP = 1D-myo-inositol hexakisphosphate + ADP + 2 H+.


ZDH11_HUMAN Palmitoyltransferase ZDHHC11 (sprot)

A palmitoyltransferase ZDHHC11 that is encoded in the genome of human.


VRTN_HUMAN Vertnin (sprot)

A vertnin that is encoded in the genome of human.


ANKZ1_HUMAN tRNA endonuclease ANKZF1 (sprot)

An ankyrin repeat and zinc finger domain-containing protein 1 that is encoded in the genome of human.


catalytic activity, acting on a tRNA

Catalytic activity that acts to modify a tRNA.


GORS2_HUMAN Golgi reassembly-stacking protein 2 (sprot)

A Golgi reassembly-stacking protein 2 that is encoded in the genome of human.


ZWILC_HUMAN Protein zwilch homolog (sprot)

A protein zwilch that is encoded in the genome of human.


REEP1_HUMAN Receptor expression-enhancing protein 1 (sprot)

A receptor expression-enhancing protein 1 that is encoded in the genome of human.


MTD2L_HUMAN Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2, mitochondrial (sprot)

A bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2, mitochondrial that is encoded in the genome of human.


histidine biosynthetic process

The chemical reactions and pathways resulting in the formation of histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid.


JUPI2_HUMAN Jupiter microtubule associated homolog 2 (sprot)

A jupiter microtubule associated homolog 2 that is encoded in the genome of human.


RN121_HUMAN E3 ubiquitin ligase RNF121 (sprot)

A RING finger protein 121 that is encoded in the genome of human.


SP14L_HUMAN Nuclear body protein SP140-like protein (sprot)

A nuclear body protein SP140-like protein that is encoded in the genome of human.


GHC1_HUMAN Mitochondrial glutamate carrier 1 (sprot)

A mitochondrial glutamate carrier 1 that is encoded in the genome of human.


PPIP2_HUMAN Proline-serine-threonine phosphatase-interacting protein 2 (sprot)

A proline-serine-threonine phosphatase-interacting protein 2 that is encoded in the genome of human.


MED20_HUMAN Mediator of RNA polymerase II transcription subunit 20 (sprot)

A mediator of RNA polymerase II transcription subunit 20 that is encoded in the genome of human.


ZN702_HUMAN Putative zinc finger protein 702 (sprot)

A putative zinc finger protein 702 that is encoded in the genome of human.


WDR76_HUMAN WD repeat-containing protein 76 (sprot)

A WD repeat-containing protein 76 that is encoded in the genome of human.


CN093_HUMAN Uncharacterized protein C14orf93 (sprot)

An uncharacterized protein C14orf93 that is encoded in the genome of human.


QTRT2_HUMAN Queuine tRNA-ribosyltransferase accessory subunit 2 (sprot)

A queuine tRNA-ribosyltransferase accessory subunit 2 that is encoded in the genome of human.


WDR54_HUMAN WD repeat-containing protein 54 (sprot)

A WD repeat-containing protein 54 that is encoded in the genome of human.


ARP8_HUMAN Actin-related protein 8 (sprot)

An actin-related protein 8 that is encoded in the genome of human.


SYP2L_HUMAN Synaptopodin 2-like protein (sprot)

A synaptopodin 2-like protein that is encoded in the genome of human.


MARH7_HUMAN E3 ubiquitin-protein ligase MARCHF7 (sprot)

An E3 ubiquitin-protein ligase MARCHF7 that is encoded in the genome of human.


ARMT1_HUMAN Damage-control phosphatase ARMT1 (sprot)

A damage-control phosphatase ARMT1 that is encoded in the genome of human.


Catalysis of the reaction: S-adenosyl-L-methionine + protein L-glutamate = S-adenosyl-L-homocysteine + protein L-glutamate 5-methyl ester; this reaction is the methylation of peptidyl-L-glutamate to form peptidyl-L-glutamate 5-methyl ester.


protein carboxyl O-methyltransferase activity

Catalysis of the transfer of a methyl group to a carboxyl group on a protein.


fructose 6-phosphate aldolase activity

Catalysis of the reaction: D-fructose-6-phosphate = dihydroxyacetone + D-glyceraldehyde-3-phosphate.


fructose-1-phosphatase activity

Catalysis of the reaction: beta-D-fructofuranose 1-phosphate + H2O <=> beta-D-fructofuranose + hydrogenphosphate.


PANK3_HUMAN Pantothenate kinase 3 (sprot)

A pantothenate kinase 3 that is encoded in the genome of human.


CNO10_HUMAN CCR4-NOT transcription complex subunit 10 (sprot)

A CCR4-NOT transcription complex subunit 10 that is encoded in the genome of human.


LRC40_HUMAN Leucine-rich repeat-containing protein 40 (sprot)

A leucine-rich repeat-containing protein 40 that is encoded in the genome of human.


RMI1_HUMAN RecQ-mediated genome instability protein 1 (sprot)

A RecQ-mediated genome instability protein 1 that is encoded in the genome of human.


EHMT1_HUMAN Histone-lysine N-methyltransferase EHMT1 (sprot)

A histone-lysine N-methyltransferase, H3 lysine-9 specific 5 that is encoded in the genome of human.


SFXN1_HUMAN Sideroflexin-1 (sprot)

A sideroflexin-1 that is encoded in the genome of human.


SPE39_HUMAN Spermatogenesis-defective protein 39 homolog (sprot)

A spermatogenesis-defective protein 39 homolog that is encoded in the genome of human.


ZN408_HUMAN Zinc finger protein 408 (sprot)

A zinc finger protein 408 that is encoded in the genome of human.


ANRA2_HUMAN Ankyrin repeat family A protein 2 (sprot)

An ankyrin repeat family A protein 2 that is encoded in the genome of human.


COG4_HUMAN Conserved oligomeric Golgi complex subunit 4 (sprot)

A conserved oligomeric Golgi complex subunit 4 that is encoded in the genome of human.


ARP5_HUMAN Actin-related protein 5 (sprot)

An actin-related protein 5 that is encoded in the genome of human.


AGO3_HUMAN Protein argonaute-3 (sprot)

A protein argonaute-3 that is encoded in the genome of human.


miRNA-mediated gene silencing by mRNA destabilization

An RNA interference pathway in which microRNAs (miRNAs) direct the cleavage of target mRNAs. Once incorporated into a RNA-induced silencing complex (RISC), a miRNA base pairing with near-perfect complementarity to the target mRNA will typically direct targeted endonucleolytic cleavage of the mRNA. Many plant miRNAs downregulate gene expression through this mechanism.


siRNA-mediated gene silencing by mRNA destabilization

An siRNA-mediated post-transcriptional gene silencing pathway in which small interfering RNAs (siRNAs) direct the cleavage of target mRNAs. Once incorporated into a RNA-induced silencing complex (RISC), an siRNA will typically direct cleavage by base pairing with perfect or near-perfect complementarity to the target mRNA.


endoribonuclease activity, cleaving miRNA-paired mRNA

Catalysis of the endonucleolytic cleavage of the mRNA in a double-stranded RNA molecule formed by the base pairing of an mRNA with an miRNA.


VP37B_HUMAN Vacuolar protein sorting-associated protein 37B (sprot)

A vacuolar protein sorting-associated protein 37B that is encoded in the genome of human.


MA6D1_HUMAN MAP6 domain-containing protein 1 (sprot)

A MAP6 domain-containing protein 1 that is encoded in the genome of human.


RM44_HUMAN Large ribosomal subunit protein mL44 (sprot)

A 39S ribosomal protein L44, mitochondrial that is encoded in the genome of human.


ribonuclease III activity

Catalysis of the endonucleolytic cleavage of RNA with 5'-phosphomonoesters and 3'-OH termini; makes two staggered cuts in both strands of dsRNA, leaving a 3' overhang of 2 nt.


UBP42_HUMAN Ubiquitin carboxyl-terminal hydrolase 42 (sprot)

A ubiquitin carboxyl-terminal hydrolase 42 that is encoded in the genome of human.


MER34_HUMAN Endogenous retroviral envelope protein HEMO (sprot)

An endogenous retroviral envelope protein HEMO that is encoded in the genome of human.


I20L2_HUMAN Interferon-stimulated 20 kDa exonuclease-like 2 (sprot)

An interferon-stimulated 20 kDa exonuclease-like 2 that is encoded in the genome of human.


KANL2_HUMAN KAT8 regulatory NSL complex subunit 2 (sprot)

A KAT8 regulatory NSL complex subunit 2 that is encoded in the genome of human.


AKIR1_HUMAN Akirin-1 (sprot)

An akirin-1 that is encoded in the genome of human.


CHODL_HUMAN Chondrolectin (sprot)

A chondrolectin that is encoded in the genome of human.


UNKL_HUMAN Putative E3 ubiquitin-protein ligase UNKL (sprot)

A RING finger protein unkempt-like that is encoded in the genome of human.


L2HDH_HUMAN L-2-hydroxyglutarate dehydrogenase, mitochondrial (sprot)

An L-2-hydroxyglutarate dehydrogenase, mitochondrial that is encoded in the genome of human.


Catalysis of the reaction: (S)-2-hydroxyglutarate + acceptor = 2-oxoglutarate + reduced acceptor.


small molecule metabolic process

The chemical reactions and pathways involving small molecules, any low molecular weight, monomeric, non-encoded molecule.


CSN7B_HUMAN COP9 signalosome complex subunit 7b (sprot)

A COP9 signalosome complex subunit 7b that is encoded in the genome of human.


NHEJ1_HUMAN Non-homologous end-joining factor 1 (sprot)

A non-homologous end-joining factor 1 that is encoded in the genome of human.


DBND1_HUMAN Dysbindin domain-containing protein 1 (sprot)

A dysbindin domain-containing protein 1 that is encoded in the genome of human.


NANOG_HUMAN Homeobox protein NANOG (sprot)

A homeobox protein NANOG that is encoded in the genome of human.


S61A2_HUMAN Protein transport protein Sec61 subunit alpha isoform 2 (sprot)

A protein transport protein Sec61 subunit alpha isoform 2 that is encoded in the genome of human.


CB39L_HUMAN Calcium-binding protein 39-like (sprot)

A calcium-binding protein 39-like that is encoded in the genome of human.


FKRP_HUMAN Ribitol 5-phosphate transferase FKRP (sprot)

A ribitol 5-phosphate transferase FKRP that is encoded in the genome of human.


pentitol metabolic process

The chemical reactions and pathways involving pentitols, any alditol with a chain of five carbon atoms in the molecule.


filtration diaphragm assembly

The aggregation, arrangement and bonding together of a set of components to form a filtration diaphragm, a specialized cell-cell junction found between the cells of the excretory system, which provides a barrier for filtration of blood or hemolymph.


skeletal muscle myofibril

A myofibril of a skeletal muscle fiber.


ELP3_HUMAN Elongator complex protein 3 (sprot)

An elongator complex protein 3 that is encoded in the genome of human.


tRNA uridine(34) acetyltransferase activity

Catalysis of the reaction: acetyl-CoA + H2O + S-adenosyl-L-methionine + uridine(34) in tRNA = 5'-deoxyadenosine + carboxymethyluridine(34) in tRNA + CoA + 2 H+ + L-methionine.


RN122_HUMAN RING finger protein 122 (sprot)

A RING finger protein 122 that is encoded in the genome of human.


JMJD4_HUMAN 2-oxoglutarate and iron-dependent oxygenase JMJD4 (sprot)

A 2-oxoglutarate and iron-dependent oxygenase JMJD4 that is encoded in the genome of human.


peptidyl-lysine 4-dioxygenase activity

Catalysis of the reaction: protein L-lysine + 2-oxoglutarate + O2 = protein 4-hydroxy-L-lysine + succinate + CO2.


RPF1_HUMAN Ribosome production factor 1 (sprot)

A ribosome production factor 1 that is encoded in the genome of human.


GPN2_HUMAN GPN-loop GTPase 2 (sprot)

A GPN-loop GTPase 2 that is encoded in the genome of human.


RPA2_HUMAN DNA-directed RNA polymerase I subunit RPA2 (sprot)

A DNA-directed RNA polymerase I subunit RPA2 that is encoded in the genome of human.


LN28A_HUMAN Protein lin-28 homolog A (sprot)

A protein lin-28 homolog A that is encoded in the genome of human.


negative regulation of glial cell differentiation

Any process that stops, prevents, or reduces the frequency, rate or extent of glia cell differentiation.


positive regulation of cell proliferation involved in kidney development

Any process that activates or increases the frequency, rate or extent of cell proliferation involved in kidney development.


ZMAT3_HUMAN Zinc finger matrin-type protein 3 (sprot)

A zinc finger matrin-type protein 3 that is encoded in the genome of human.


UCK1_HUMAN Uridine-cytidine kinase 1 (sprot)

A uridine-cytidine kinase 1 that is encoded in the genome of human.


KT3K_HUMAN Ketosamine-3-kinase (sprot)

A ketosamine-3-kinase that is encoded in the genome of human.


TBC17_HUMAN TBC1 domain family member 17 (sprot)

A TBC1 domain family member 17 that is encoded in the genome of human.


CAHM2_HUMAN Calcium homeostasis modulator protein 2 (sprot)

A calcium homeostasis modulator protein 2 that is encoded in the genome of human.


SYCM_HUMAN Probable cysteine--tRNA ligase, mitochondrial (sprot)

A probable cysteine--tRNA ligase, mitochondrial that is encoded in the genome of human.


CERS4_HUMAN Ceramide synthase 4 (sprot)

A ceramide synthase 4 that is encoded in the genome of human.


EFCC1_HUMAN EF-hand and coiled-coil domain-containing protein 1 (sprot)

An EF-hand and coiled-coil domain-containing protein 1 that is encoded in the genome of human.


RSAD1_HUMAN Radical S-adenosyl methionine domain-containing protein 1, mitochondrial (sprot)

A radical S-adenosyl methionine domain-containing protein 1, mitochondrial that is encoded in the genome of human.


S52A2_HUMAN Solute carrier family 52, riboflavin transporter, member 2 (sprot)

A solute carrier family 52, riboflavin transporter, member 2 that is encoded in the genome of human.


riboflavin transmembrane transporter activity

Enables the transfer of riboflavin from one side of a membrane to the other. Riboflavin (vitamin B2) is a water-soluble B-complex vitamin, converted in the cell to FMN and FAD, cofactors required for the function of flavoproteins.


4-hydroxybutyrate receptor activity

Combining with 4-hydroxybutyrte to initiate a change in cell activity.


PPCS_HUMAN Phosphopantothenate--cysteine ligase (sprot)

A phosphopantothenate--cysteine ligase that is encoded in the genome of human.


Catalysis of the reaction: CTP + (R)-4'-phosphopantothenate + L-cysteine = CMP + diphosphate + (R)-4'-phosphopantothenoyl-L-cysteine. Cysteine can be replaced by some of its derivatives.


SUCHY_HUMAN Succinate--hydroxymethylglutarate CoA-transferase (sprot)

An acetyl-CoA:oxalate CoA-transferase that is encoded in the genome of human.


Catalysis of the reaction: (S)-3-hydroxy-3-methylglutarate + succinyl-CoA = 3-hydroxy-3-methyl-glutaryl-CoA + succinate.


UBTD1_HUMAN Ubiquitin domain-containing protein 1 (sprot)

A ubiquitin domain-containing protein 1 that is encoded in the genome of human.


WDR41_HUMAN WD repeat-containing protein 41 (sprot)

A WD repeat-containing protein 41 that is encoded in the genome of human.


CLXN_HUMAN Calaxin (sprot)

A calaxin that is encoded in the genome of human.


EAF6_HUMAN Chromatin modification-related protein MEAF6 (sprot)

A chromatin modification-related protein MEAF6 that is encoded in the genome of human.


ZN556_HUMAN Zinc finger protein 556 (sprot)

A zinc finger protein 556 that is encoded in the genome of human.


TASL_HUMAN TLR adapter interacting with SLC15A4 on the lysosome (sprot)

A TLR adapter interacting with SLC15A4 on the lysosome that is encoded in the genome of human.


SP30L_HUMAN Histone deacetylase complex subunit SAP30L (sprot)

A histone deacetylase complex subunit SAP30L that is encoded in the genome of human.


COE2_HUMAN Transcription factor COE2 (sprot)

A transcription factor COE2 that is encoded in the genome of human.


NMNA1_HUMAN Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 (sprot)

A nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 that is encoded in the genome of human.


Catalysis of the reaction: ATP + nicotinamide nucleotide = diphosphate + NAD+.


MLXIP_HUMAN MLX-interacting protein (sprot)

An MLX-interacting protein that is encoded in the genome of human.


LIN7B_HUMAN Protein lin-7 homolog B (sprot)

A protein lin-7 homolog B that is encoded in the genome of human.


KIF9_HUMAN Kinesin-like protein KIF9 (sprot)

A kinesin-like protein KIF9 that is encoded in the genome of human.


AGRL3_HUMAN Adhesion G protein-coupled receptor L3 (sprot)

An adhesion G protein-coupled receptor L3 that is encoded in the genome of human.


NJMU_HUMAN Protein Njmu-R1 (sprot)

A protein Njmu-R1 that is encoded in the genome of human.


S28A3_HUMAN Solute carrier family 28 member 3 (sprot)

A solute carrier family 28 member 3 that is encoded in the genome of human.


ROP1A_HUMAN Ropporin-1A (sprot)

A ropporin-1A that is encoded in the genome of human.


LMA1L_HUMAN Protein ERGIC-53-like (sprot)

A protein ERGIC-53-like that is encoded in the genome of human.


SIAE_HUMAN Sialate O-acetylesterase (sprot)

A sialate O-acetylesterase that is encoded in the genome of human.


sialate O-acetylesterase activity

Catalysis of the reaction: N-acetyl-O-acetylneuraminate (free or glycosidically bound) + H2O = N-acetylneuraminate + acetate.


sialate 9-O-acetylesterase activity

Catalysis of the reaction: H2O + N-acetyl-9-O-acetylneuraminate = acetate + H+ + N-acetylneuraminate.


sialate 4-O-acetylesterase activity

Catalysis of the reaction: H2O + N-acetyl-4-O-acetylneuraminate = acetate + H+ + N-acetylneuraminate.


PELI2_HUMAN E3 ubiquitin-protein ligase pellino homolog 2 (sprot)

An E3 ubiquitin-protein ligase pellino homolog 2 that is encoded in the genome of human.


PKHA5_HUMAN Pleckstrin homology domain-containing family A member 5 (sprot)

A pleckstrin homology domain-containing family A member 5 that is encoded in the genome of human.


SMUF2_HUMAN E3 ubiquitin-protein ligase SMURF2 (sprot)

An E3 ubiquitin-protein ligase SMURF2 that is encoded in the genome of human.


RENT2_HUMAN Regulator of nonsense transcripts 2 (sprot)

A regulator of nonsense transcripts 2 that is encoded in the genome of human.


TCTP8_HUMAN Putative translationally-controlled tumor protein-like protein TPT1P8 (sprot)


RNPL1_HUMAN Aminopeptidase RNPEPL1 (sprot)

An aminopeptidase RNPEPL1 that is encoded in the genome of human.


GBB4_HUMAN Guanine nucleotide-binding protein subunit beta-4 (sprot)

A guanine nucleotide-binding protein subunit beta-4 that is encoded in the genome of human.


XPO5_HUMAN Exportin-5 (sprot)

An exportin-5 that is encoded in the genome of human.


TNR27_HUMAN Tumor necrosis factor receptor superfamily member 27 (sprot)

A tumor necrosis factor receptor superfamily member 27 that is encoded in the genome of human.


GRPE1_HUMAN GrpE protein homolog 1, mitochondrial (sprot)

A GrpE protein homolog 1, mitochondrial that is encoded in the genome of human.


BRF2_HUMAN Transcription factor IIIB 50 kDa subunit (sprot)

A transcription factor IIIB 50 kDa subunit that is encoded in the genome of human.


CLSPN_HUMAN Claspin (sprot)

A claspin that is encoded in the genome of human.


UD17_HUMAN UDP-glucuronosyltransferase 1A7 (sprot)

A protein that is a translation product of the UGT1A7 gene in human.


UD110_HUMAN UDP-glucuronosyltransferase 1A10 (sprot)

A UDP-glucuronosyltransferase 1A10 that is encoded in the genome of human.


UD18_HUMAN UDP-glucuronosyltransferase 1A8 (sprot)

A UDP-glucuronosyltransferase 1A8 that is encoded in the genome of human.


MAGF1_HUMAN Melanoma-associated antigen F1 (sprot)

A melanoma-associated antigen F1 that is encoded in the genome of human.


BCDO1_HUMAN Beta,beta-carotene 15,15'-dioxygenase (sprot)

A beta,beta-carotene 15,15'-dioxygenase that is encoded in the genome of human.


Catalysis of the reaction: all-trans-beta-carotene + O2 = 2 all-trans-retinal.


vitamin A biosynthetic process

The chemical reactions and pathways resulting in the formation of any of the vitamin A compounds, retinol, retinal (retinaldehyde) and retinoic acid. Animals cannot synthesize vitamin A de novo, but form it through oxidative cleavage of carotenoids.


beta-carotene metabolic process

The chemical reactions and pathways involving beta-carotene.


CLK4_HUMAN Dual specificity protein kinase CLK4 (sprot)

A dual specificity protein kinase CLK4 that is encoded in the genome of human.


PRD16_HUMAN Histone-lysine N-methyltransferase PRDM16 (sprot)

A histone-lysine N-methyltransferase PRDM16 that is encoded in the genome of human.


ELOV3_HUMAN Elongation of very long chain fatty acids protein 3 (sprot)

An elongation of very long chain fatty acids protein 3 that is encoded in the genome of human.


MYG1_HUMAN MYG1 exonuclease (sprot)

A MYG1 exonuclease that is encoded in the genome of human.


B2L12_HUMAN Bcl-2-like protein 12 (sprot)

A Bcl-2-like protein 12 that is encoded in the genome of human.


KCNKD_HUMAN Potassium channel subfamily K member 13 (sprot)

A potassium channel subfamily K member 13 that is encoded in the genome of human.


KCNKC_HUMAN Potassium channel subfamily K member 12 (sprot)

A potassium channel subfamily K member 12 that is encoded in the genome of human.


PKHA2_HUMAN Pleckstrin homology domain-containing family A member 2 (sprot)

A pleckstrin homology domain-containing family A member 2 that is encoded in the genome of human.


PKHA3_HUMAN Pleckstrin homology domain-containing family A member 3 (sprot)

A pleckstrin homology domain-containing family A member 3 that is encoded in the genome of human.


PKHA1_HUMAN Pleckstrin homology domain-containing family A member 1 (sprot)

A pleckstrin homology domain-containing family A member 1 that is encoded in the genome of human.


ILRL2_HUMAN Interleukin-1 receptor-like 2 (sprot)

An interleukin-1 receptor-like 2 that is encoded in the genome of human.


SEBOX_HUMAN Homeobox protein SEBOX (sprot)

A homeobox protein SEBOX that is encoded in the genome of human.


RISC_HUMAN Retinoid-inducible serine carboxypeptidase (sprot)

A retinoid-inducible serine carboxypeptidase that is encoded in the genome of human.


CP343_HUMAN Cytochrome P450 3A43 (sprot)

A cytochrome P450 3A43 that is encoded in the genome of human.


SP110_HUMAN Sp110 nuclear body protein (sprot)

An Sp110 nuclear body protein that is encoded in the genome of human.


NET4_HUMAN Netrin-4 (sprot)

A netrin-4 that is encoded in the genome of human.