TDRKH_HUMAN Tudor and KH domain-containing protein (sprot)

A tudor and KH domain-containing protein that is encoded in the genome of human.


CSEN_HUMAN Calsenilin (sprot)

A calsenilin that is encoded in the genome of human.


MED16_HUMAN Mediator of RNA polymerase II transcription subunit 16 (sprot)

A mediator of RNA polymerase II transcription subunit 16 that is encoded in the genome of human.


NOP58_HUMAN Nucleolar protein 58 (sprot)

A nucleolar protein 58 that is encoded in the genome of human.


GIT1_HUMAN ARF GTPase-activating protein GIT1 (sprot)

An ARF GTPase-activating protein GIT1 that is encoded in the genome of human.


UB2D4_HUMAN Ubiquitin-conjugating enzyme E2 D4 (sprot)

A ubiquitin-conjugating enzyme E2 D4 that is encoded in the genome of human.


ZN281_HUMAN Zinc finger protein 281 (sprot)

A zinc finger protein 281 that is encoded in the genome of human.


AR2BP_HUMAN ADP-ribosylation factor-like protein 2-binding protein (sprot)

An ADP-ribosylation factor-like protein 2-binding protein that is encoded in the genome of human.


RPC10_HUMAN DNA-directed RNA polymerase III subunit RPC10 (sprot)

A DNA-directed RNA polymerase III subunit RPC10 that is encoded in the genome of human.


ZBT32_HUMAN Zinc finger and BTB domain-containing protein 32 (sprot)

A zinc finger and BTB domain-containing protein 32 that is encoded in the genome of human.


TMM98_HUMAN Transmembrane protein 98 (sprot)

A transmembrane protein 98 that is encoded in the genome of human.


PRG3_HUMAN Proteoglycan 3 (sprot)

A proteoglycan 3 that is encoded in the genome of human.


basophil activation

biolink:BiologicalProcess biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:Occurrent biolink:OntologyClass biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

The change in morphology and behavior of a basophil resulting from exposure to a cytokine, chemokine, soluble factor, or to (at least in mammals) an antigen which the basophil has specifically bound via IgE bound to Fc-epsilonRI receptors.


KLF13_HUMAN Krueppel-like factor 13 (sprot)

A krueppel-like factor 13 that is encoded in the genome of human.


SGT1_HUMAN Protein SGT1 homolog (sprot)

A protein SGT1 that is encoded in the genome of human.


MTO1_HUMAN Protein MTO1 homolog, mitochondrial (sprot)

A protein MTO1, mitochondrial that is encoded in the genome of human.


SYYM_HUMAN Tyrosine--tRNA ligase, mitochondrial (sprot)

A tyrosine--tRNA ligase, mitochondrial that is encoded in the genome of human.


The process of coupling tyrosine to tyrosyl-tRNA in a mitochondrion, catalyzed by tyrosyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.


COQ6_HUMAN Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial (sprot)

A ubiquinone biosynthesis monooxygenase COQ6, mitochondrial that is encoded in the genome of human.


biolink:MolecularActivity biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:Occurrent biolink:OntologyClass biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

Catalysis of the reaction: 2-octaprenyl-6-methoxyphenol + O2 + 4 H+ = 2-octaprenyl-6-methoxy-1,4-benzoquinol + H2O.


4-hydroxy-3-all-trans-hexaprenylbenzoate + 2 H+ + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = 3,4-dihydroxy-5-all-trans-hexaprenylbenzoate + H2O + 2 oxidized [2Fe-2S]-[ferredoxin].


NAGA_HUMAN N-acetylglucosamine-6-phosphate deacetylase (sprot)

A eukaryotic-type N-acetylglucosamine-6-phosphate deacetylase that is encoded in the genome of human.


Catalysis of the reaction: N-acetyl-D-glucosamine 6-phosphate + H2O = D-glucosamine 6-phosphate + acetate.


Catalysis of the reaction: H2O + N-acetyl-D-galactosamine 6-phosphate = acetate + D-galactosamine 6-phosphate.


ACOT9_HUMAN Acyl-coenzyme A thioesterase 9, mitochondrial (sprot)

An acyl-coenzyme A thioesterase 9, mitochondrial that is encoded in the genome of human.


AAR2_HUMAN Protein AAR2 homolog (sprot)

A protein AAR2 homolog that is encoded in the genome of human.


NOSIP_HUMAN Nitric oxide synthase-interacting protein (sprot)

A nitric oxide synthase-interacting protein that is encoded in the genome of human.


DEOC_HUMAN Deoxyribose-phosphate aldolase (sprot)

A deoxyribose-phosphate aldolase that is encoded in the genome of human.


deoxyribose-phosphate aldolase activity

Catalysis of the reaction: 2-deoxy-D-ribose 5-phosphate = D-glyceraldehyde 3-phosphate + acetaldehyde.


deoxyribonucleoside catabolic process

The chemical reactions and pathways resulting in the breakdown of any one of a family of organic molecules consisting of a purine or pyrimidine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside).


deoxyribose phosphate catabolic process

The chemical reactions and pathways resulting in the breakdown of deoxyribose phosphate, the phosphorylated sugar 2-deoxy-erythro-pentose.


MEMO1_HUMAN Protein MEMO1 (sprot)

A protein MEMO1 that is encoded in the genome of human.


TMX2_HUMAN Thioredoxin-related transmembrane protein 2 (sprot)

A thioredoxin-related transmembrane protein 2 that is encoded in the genome of human.


FCF1_HUMAN rRNA-processing protein FCF1 homolog (sprot)

An rRNA-processing protein FCF1 that is encoded in the genome of human.


NSG2_HUMAN Neuronal vesicle trafficking-associated protein 2 (sprot)

A neuronal vesicle trafficking-associated protein 2 that is encoded in the genome of human.


ZBT12_HUMAN Zinc finger and BTB domain-containing protein 12 (sprot)

A zinc finger and BTB domain-containing protein 12 that is encoded in the genome of human.


LSM2_HUMAN U6 snRNA-associated Sm-like protein LSm2 (sprot)

A U6 snRNA-associated Sm-like protein LSm2 that is encoded in the genome of human.


VWA7_HUMAN von Willebrand factor A domain-containing protein 7 (sprot)

A von Willebrand factor A domain-containing protein 7 that is encoded in the genome of human.


SIGL9_HUMAN Sialic acid-binding Ig-like lectin 9 (sprot)

A sialic acid-binding Ig-like lectin 9 that is encoded in the genome of human.


KLK5_HUMAN Kallikrein-5 (sprot)

A kallikrein-5 that is encoded in the genome of human.


PLLP_HUMAN Plasmolipin (sprot)

A plasmolipin that is encoded in the genome of human.


SNX24_HUMAN Sorting nexin-24 (sprot)

A sorting nexin-24 that is encoded in the genome of human.


SC6A5_HUMAN Sodium- and chloride-dependent glycine transporter 2 (sprot)

A sodium- and chloride-dependent glycine transporter 2 that is encoded in the genome of human.


STA10_HUMAN START domain-containing protein 10 (sprot)

A START domain-containing protein 10 that is encoded in the genome of human.


IFT52_HUMAN Intraflagellar transport protein 52 homolog (sprot)

An intraflagellar transport protein 52 that is encoded in the genome of human.


SHLB1_HUMAN Endophilin-B1 (sprot)

An endophilin-B1 that is encoded in the genome of human.


protein localization to vacuolar membrane

A process in which a protein is transported to, or maintained in, a location within a vacuolar membrane.


CIA30_HUMAN Complex I intermediate-associated protein 30, mitochondrial (sprot)

A complex I intermediate-associated protein 30, mitochondrial that is encoded in the genome of human.


CAB39_HUMAN Calcium-binding protein 39 (sprot)

A calcium-binding protein 39 that is encoded in the genome of human.


LC7L2_HUMAN Putative RNA-binding protein Luc7-like 2 (sprot)

A putative RNA-binding protein Luc7-like 2 that is encoded in the genome of human.


UB2J1_HUMAN Ubiquitin-conjugating enzyme E2 J1 (sprot)

A ubiquitin-conjugating enzyme E2 J1 that is encoded in the genome of human.


RBMX2_HUMAN RNA-binding motif protein, X-linked 2 (sprot)

An RNA-binding motif protein, X-linked 2 that is encoded in the genome of human.


DHRS7_HUMAN Dehydrogenase/reductase SDR family member 7 (sprot)

A dehydrogenase/reductase SDR family member 7 that is encoded in the genome of human.


ZDHC9_HUMAN Palmitoyltransferase ZDHHC9 (sprot)

A palmitoyltransferase ZDHHC9 that is encoded in the genome of human.


Ras palmitoyltransferase activity

Catalysis of the reaction: palmitoyl-CoA + protein-cysteine = S-palmitoyl protein + CoA, specific for Ras proteins.


RT02_HUMAN Small ribosomal subunit protein uS2m (sprot)

A 28S ribosomal protein S2, mitochondrial that is encoded in the genome of human.


COQ4_HUMAN Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial (sprot)

A ubiquinone biosynthesis protein COQ4, mitochondrial that is encoded in the genome of human.


UTP11_HUMAN Probable U3 small nucleolar RNA-associated protein 11 (sprot)

A probable U3 small nucleolar RNA-associated protein 11 that is encoded in the genome of human.


PHOCN_HUMAN MOB-like protein phocein (sprot)

A MOB-like protein phocein that is encoded in the genome of human.


RRP7A_HUMAN Ribosomal RNA-processing protein 7 homolog A (sprot)

A ribosomal RNA-processing protein 7 homolog A that is encoded in the genome of human.


SBDS_HUMAN Ribosome maturation protein SBDS (sprot)

A ribosome maturation protein SBDS that is encoded in the genome of human.


TMED5_HUMAN Transmembrane emp24 domain-containing protein 5 (sprot)

A transmembrane emp24 domain-containing protein 5 that is encoded in the genome of human.


PLD3B_HUMAN PRELI domain containing protein 3B (sprot)

A PRELI domain containing protein 3B that is encoded in the genome of human.


EXOS1_HUMAN Exosome complex component CSL4 (sprot)

An exosome complex component CSL4 that is encoded in the genome of human.


TMED7_HUMAN Transmembrane emp24 domain-containing protein 7 (sprot)

A transmembrane emp24 domain-containing protein 7 that is encoded in the genome of human.


SF3B6_HUMAN Splicing factor 3B subunit 6 (sprot)

A splicing factor 3B subunit 6 that is encoded in the genome of human.


EMC9_HUMAN ER membrane protein complex subunit 9 (sprot)

An ER membrane protein complex subunit 9 that is encoded in the genome of human.


RM11_HUMAN Large ribosomal subunit protein uL11m (sprot)

A 39S ribosomal protein L11, mitochondrial that is encoded in the genome of human.


ORN_HUMAN Oligoribonuclease, mitochondrial (sprot)

An oligoribonuclease, mitochondrial that is encoded in the genome of human.


WASC3_HUMAN WASH complex subunit 3 (sprot)

A WASH complex subunit 3 that is encoded in the genome of human.


NOP16_HUMAN Nucleolar protein 16 (sprot)

A nucleolar protein 16 that is encoded in the genome of human.


TPRKB_HUMAN EKC/KEOPS complex subunit TPRKB (sprot)

An EKC/KEOPS complex subunit TPRKB that is encoded in the genome of human.


RNF11_HUMAN RING finger protein 11 (sprot)

A RING finger protein 11 that is encoded in the genome of human.


PPIL1_HUMAN Peptidyl-prolyl cis-trans isomerase-like 1 (sprot)

A peptidyl-prolyl cis-trans isomerase-like 1 that is encoded in the genome of human.


MED31_HUMAN Mediator of RNA polymerase II transcription subunit 31 (sprot)

A mediator of RNA polymerase II transcription subunit 31 that is encoded in the genome of human.


UFC1_HUMAN Ubiquitin-fold modifier-conjugating enzyme 1 (sprot)

A ubiquitin-fold modifier-conjugating enzyme 1 that is encoded in the genome of human.


UFM1 conjugating enzyme activity

Isoenergetic transfer of UFM1 from one protein to another via the reaction X-UFM1 + Y = Y-UFM1 + X, where both the X-UFM1 and Y-UFM1 linkages are thioester bonds between the C-terminal amino acid of UFM1 and a sulfhydryl side group of a cysteine residue.


CIA2B_HUMAN Cytosolic iron-sulfur assembly component 2B (sprot)

A cytosolic iron-sulfur assembly component 2B that is encoded in the genome of human.


MSRB2_HUMAN Methionine-R-sulfoxide reductase B2, mitochondrial (sprot)

A methionine-R-sulfoxide reductase B2, mitochondrial that is encoded in the genome of human.


RT16_HUMAN Small ribosomal subunit protein bS16m (sprot)

A 28S ribosomal protein S16, mitochondrial that is encoded in the genome of human.


RT18C_HUMAN Small ribosomal subunit protein bS18m (sprot)

A 28S ribosomal protein S18c, mitochondrial that is encoded in the genome of human.


FIS1_HUMAN Mitochondrial fission 1 protein (sprot)

A mitochondrial fission 1 protein that is encoded in the genome of human.


negative regulation of fatty acid transport

Any process that stops, prevents, or reduces the frequency, rate or extent of fatty acid transport.


TIM16_HUMAN Mitochondrial import inner membrane translocase subunit TIM16 (sprot)

A mitochondrial import inner membrane translocase subunit Tim16 that is encoded in the genome of human.


PAM complex, Tim23 associated import motor

biolink:CellularComponent biolink:AnatomicalEntity biolink:OrganismalEntity biolink:BiologicalEntity biolink:NamedThing biolink:PhysicalEssence biolink:SubjectOfInvestigation biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

Protein complex located on the matrix side of the mitochondrial inner membrane and associated with the TIM23 mitochondrial import inner membrane translocase complex (GO:0005744); ATPase motor activity to drive import of proteins into the mitochondrial matrix.


KAD6_HUMAN Adenylate kinase isoenzyme 6 (sprot)

An adenylate kinase isoenzyme 6 that is encoded in the genome of human.


RT23_HUMAN Small ribosomal subunit protein mS23 (sprot)

A 28S ribosomal protein S23, mitochondrial that is encoded in the genome of human.


GOT1B_HUMAN Vesicle transport protein GOT1B (sprot)

A vesicle transport protein GOT1B that is encoded in the genome of human.


HDGR3_HUMAN Hepatoma-derived growth factor-related protein 3 (sprot)

A hepatoma-derived growth factor-related protein 3 that is encoded in the genome of human.


BOLA1_HUMAN BolA-like protein 1 (sprot)

A BolA-like protein 1 that is encoded in the genome of human.


PTH2_HUMAN Peptidyl-tRNA hydrolase 2, mitochondrial (sprot)

A peptidyl-tRNA hydrolase 2, mitochondrial that is encoded in the genome of human.


CHMP3_HUMAN Charged multivesicular body protein 3 (sprot)

A charged multivesicular body protein 3 that is encoded in the genome of human.


STRAP_HUMAN Serine-threonine kinase receptor-associated protein (sprot)

A serine-threonine kinase receptor-associated protein that is encoded in the genome of human.


RTCB_HUMAN RNA-splicing ligase RtcB homolog (sprot)

An RNA-splicing ligase RtcB that is encoded in the genome of human.


FBX7_HUMAN F-box only protein 7 (sprot)

An F-box only protein 7 that is encoded in the genome of human.


negative regulation of lymphocyte differentiation

Any process that stops, prevents, or reduces the frequency, rate or extent of lymphocyte differentiation.


glial cytoplasmic inclusion

Non-membrane-bound cytoplasmic inclusions composed of 10-40 nm granule-coated fibrils. These inclusions have an abnormal accumulation of alpha-synuclein protein and are found in association with multiple system atrophy.


classical Lewy body

Cytoplasmic inclusion, 5 to 15 micrometers in diameter, with a dense core surrounded by a halo of 10 to 20 nm wide radially oriented alpha-synuclein fibrils.


Lewy neurite

Elongated neuronal process, often with side branches and more than one branching point, described in brains of patients with Parkinson's disease. Lewy neurites stain positively for ubiquitin in brainstem and forebrain regions affected in Parkinson's disease.


Lewy body corona

The periphery of a Lewy body. In Parkinson's disease, it contains spherical accumulations of filaments arranged in a loose, radiating array.


3BP1_HUMAN SH3 domain-binding protein 1 (sprot)

An SH3 domain-binding protein 1 that is encoded in the genome of human.


RAP2C_HUMAN Ras-related protein Rap-2c (sprot)

A Ras-related protein Rap-2c that is encoded in the genome of human.


CBY1_HUMAN Protein chibby homolog 1 (sprot)

A protein chibby homolog 1 that is encoded in the genome of human.


STA13_HUMAN StAR-related lipid transfer protein 13 (sprot)

A StAR-related lipid transfer protein 13 that is encoded in the genome of human.


ZN337_HUMAN Zinc finger protein 337 (sprot)

A zinc finger protein 337 that is encoded in the genome of human.


OR2W1_HUMAN Olfactory receptor 2W1 (sprot)

An olfactory receptor 2W1 that is encoded in the genome of human.


RHBD3_HUMAN Rhomboid domain-containing protein 3 (sprot)

A rhomboid domain-containing protein 3 that is encoded in the genome of human.


SIT1_HUMAN Signaling threshold-regulating transmembrane adapter 1 (sprot)

A signaling threshold-regulating transmembrane adapter 1 that is encoded in the genome of human.


RBGP1_HUMAN Rab GTPase-activating protein 1 (sprot)

A Rab GTPase-activating protein 1 that is encoded in the genome of human.


NALD2_HUMAN N-acetylated-alpha-linked acidic dipeptidase 2 (sprot)

An N-acetylated-alpha-linked acidic dipeptidase 2 that is encoded in the genome of human.


TMED3_HUMAN Transmembrane emp24 domain-containing protein 3 (sprot)

A transmembrane emp24 domain-containing protein 3 that is encoded in the genome of human.


HCN4_HUMAN Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (sprot)

A potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 that is encoded in the genome of human.


voltage-gated potassium channel activity involved in SA node cell action potential depolarization

Enables the transmembrane transfer of a potassium ion by a voltage-gated channel through the plasma membrane of an SA node cardiac muscle cell contributing to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.


ADA18_HUMAN Disintegrin and metalloproteinase domain-containing protein 18 (sprot)

A disintegrin and metalloproteinase domain-containing protein 18 that is encoded in the genome of human.


T22D4_HUMAN TSC22 domain family protein 4 (sprot)

A TSC22 domain family protein 4 that is encoded in the genome of human.


GRIP1_HUMAN Glutamate receptor-interacting protein 1 (sprot)

A glutamate receptor-interacting protein 1 that is encoded in the genome of human.


NEUR2_HUMAN Sialidase-2 (sprot)

A sialidase-2 that is encoded in the genome of human.


DOP2_HUMAN Protein dopey-2 (sprot)

A protein dopey-2 that is encoded in the genome of human.


WNK2_HUMAN Serine/threonine-protein kinase WNK2 (sprot)

A serine/threonine-protein kinase WNK2 that is encoded in the genome of human.


ZN330_HUMAN Zinc finger protein 330 (sprot)

A zinc finger protein 330 that is encoded in the genome of human.


R3HC1_HUMAN R3H and coiled-coil domain-containing protein 1 (sprot)

An R3H and coiled-coil domain-containing protein 1 that is encoded in the genome of human.


NOC2L_HUMAN Nucleolar complex protein 2 homolog (sprot)

A nucleolar complex protein 2 that is encoded in the genome of human.


RL36_HUMAN Large ribosomal subunit protein eL36 (sprot)

A 60S ribosomal protein L36 that is encoded in the genome of human.


RWDD3_HUMAN RWD domain-containing protein 3 (sprot)

An RWD domain-containing protein 3 that is encoded in the genome of human.


positive regulation of hypoxia-inducible factor-1alpha signaling pathway

Any process that activates or increases the frequency, rate or extent of hypoxia-inducible factor-1alpha signaling pathway.


CCDC9_HUMAN Coiled-coil domain-containing protein 9 (sprot)

A coiled-coil domain-containing protein 9 that is encoded in the genome of human.


CHTOP_HUMAN Chromatin target of PRMT1 protein (sprot)

A chromatin target of PRMT1 protein that is encoded in the genome of human.


PYGO1_HUMAN Pygopus homolog 1 (sprot)

A pygopus homolog 1 that is encoded in the genome of human.


SAMH1_HUMAN Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 (sprot)

A deoxynucleoside triphosphate triphosphohydrolase SAMHD1 that is encoded in the genome of human.


dGTPase activity

Catalysis of the reaction: dGTP + H2O = 2'-deoxyguanosine + 2 H+ + triphosphate.


triphosphoric monoester hydrolase activity

Catalysis of the hydrolysis of a triphosphoester to give a triphosphate group and a free hydroxyl group.


dGTP binding

Binding to dGTP, deoxyguanosine triphosphate.


deoxynucleoside triphosphate hydrolase activity

Catalysis of the reaction: dNTP + H2O = 2'-deoxynucleoside + H+ + triphosphate.


deoxyribonucleotide catabolic process

The chemical reactions and pathways resulting in the breakdown of a deoxyribonucleotide, a compound consisting of deoxyribonucleoside (a base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.


FA32A_HUMAN Protein FAM32A (sprot)

A protein FAM32A that is encoded in the genome of human.


C2CD2_HUMAN C2 domain-containing protein 2 (sprot)

A C2 domain-containing protein 2 that is encoded in the genome of human.


CV024_HUMAN Putative uncharacterized protein YWHAH-AS1 (sprot)


PKP3_HUMAN Plakophilin-3 (sprot)

A plakophilin-3 that is encoded in the genome of human.


SKAP_HUMAN Small kinetochore-associated protein (sprot)

A small kinetochore-associated protein that is encoded in the genome of human.


HBS1L_HUMAN HBS1-like protein (sprot)

An HBS1-like protein that is encoded in the genome of human.


TBX22_HUMAN T-box transcription factor TBX22 (sprot)

A T-box transcription factor TBX22 that is encoded in the genome of human.


ZN711_HUMAN Zinc finger protein 711 (sprot)

A zinc finger protein 711 that is encoded in the genome of human.


DYR1B_HUMAN Dual specificity tyrosine-phosphorylation-regulated kinase 1B (sprot)

A dual specificity tyrosine-phosphorylation-regulated kinase 1B that is encoded in the genome of human.


NR2E1_HUMAN Nuclear receptor subfamily 2 group E member 1 (sprot)

A nuclear receptor subfamily 2 group E member 1 that is encoded in the genome of human.


forebrain generation of neurons

The process in which nerve cells are generated in the forebrain. This includes the production of neuroblasts from and their differentiation into neurons.


SALL2_HUMAN Sal-like protein 2 (sprot)

A Sal-like protein 2 that is encoded in the genome of human.


LMBL1_HUMAN Lethal(3)malignant brain tumor-like protein 1 (sprot)

A lethal(3)malignant brain tumor-like protein 1 that is encoded in the genome of human.


SAM domain binding

Binding to a SAM (Sterile Alpha Motif) domain, which is a 70-amino acid protein sequence that participates in protein-protein, protein-lipid, and protein-RNA interactions and is conserved from lower to higher eukaryotes.


CMAH_HUMAN Inactive cytidine monophosphate-N-acetylneuraminic acid hydroxylase (sprot)

A protein that is a translation product of the CMAHP gene in human.


Catalysis of the reaction: CMP-N-acetylneuraminate + NADPH + H+ + O2 = CMP-N-glycoloylneuraminate + NADP+ + H2O.


ZN175_HUMAN Zinc finger protein 175 (sprot)

A zinc finger protein 175 that is encoded in the genome of human.


AAKB1_HUMAN 5'-AMP-activated protein kinase subunit beta-1 (sprot)

A 5'-AMP-activated protein kinase subunit beta-1 that is encoded in the genome of human.


MTF2_HUMAN Metal-response element-binding transcription factor 2 (sprot)

A metal-response element-binding transcription factor 2 that is encoded in the genome of human.


WIPI4_HUMAN WD repeat domain phosphoinositide-interacting protein 4 (sprot)

A WD repeat domain phosphoinositide-interacting protein 4 that is encoded in the genome of human.


VPP2_HUMAN V-type proton ATPase 116 kDa subunit a 2 (sprot)

A V-type proton ATPase 116 kDa subunit a 2 that is encoded in the genome of human.


TLN1_HUMAN Talin-1 (sprot)

A talin-1 that is encoded in the genome of human.


ZAN_HUMAN Zonadhesin (sprot)

A zonadhesin that is encoded in the genome of human.


KIF3A_HUMAN Kinesin-like protein KIF3A (sprot)

A kinesin-like protein KIF3A that is encoded in the genome of human.


JERKL_HUMAN Jerky protein homolog-like (sprot)

A jerky protein homolog-like that is encoded in the genome of human.


TRRAP_HUMAN Transformation/transcription domain-associated protein (sprot)

A transformation/transcription domain-associated protein that is encoded in the genome of human.


NF2L3_HUMAN Nuclear factor erythroid 2-related factor 3 (sprot)

A nuclear factor erythroid 2-related factor 3 that is encoded in the genome of human.


O10H1_HUMAN Olfactory receptor 10H1 (sprot)

An olfactory receptor 10H1 that is encoded in the genome of human.


ARIP4_HUMAN Helicase ARIP4 (sprot)

A helicase ARIP4 that is encoded in the genome of human.


MTCL1_HUMAN Microtubule cross-linking factor 1 (sprot)

A microtubule cross-linking factor 1 that is encoded in the genome of human.


DCAF1_HUMAN DDB1- and CUL4-associated factor 1 (sprot)

A DDB1- and CUL4-associated factor 1 that is encoded in the genome of human.


histone H2AT120 kinase activity

Catalysis of the reaction: histone H2A-threonine (position 120) + ATP = histone H2A-phosphothreonine (position 120) + ADP. This reaction is the addition of a phosphate group to the threonine residue at position 120 of histone H2A.


cell competition in a multicellular organism

Competitive interactions within multicellular organisms between cell populations that differ in growth rates, leading to the elimination of the slowest-growing cells.


NRX3A_HUMAN Neurexin-3 (sprot)

A neurexin-3-alpha that is encoded in the genome of human.


KDM3A_HUMAN Lysine-specific demethylase 3A (sprot)

A lysine-specific demethylase 3A that is encoded in the genome of human.


formaldehyde biosynthetic process

The chemical reactions and pathways resulting in the formation of formaldehyde (methanal, H2C=O), the simplest aldehyde.


TCAF1_HUMAN TRPM8 channel-associated factor 1 (sprot)

A TRPM8 channel-associated factor 1 that is encoded in the genome of human.


MFHA1_HUMAN Malignant fibrous histiocytoma-amplified sequence 1 (sprot)

A malignant fibrous histiocytoma-amplified sequence 1 that is encoded in the genome of human.


CHST2_HUMAN Carbohydrate sulfotransferase 2 (sprot)

A carbohydrate sulfotransferase 2 that is encoded in the genome of human.


RBM19_HUMAN Probable RNA-binding protein 19 (sprot)

A probable RNA-binding protein 19 that is encoded in the genome of human.


DAAM1_HUMAN Disheveled-associated activator of morphogenesis 1 (sprot)

A disheveled-associated activator of morphogenesis 1 that is encoded in the genome of human.


DGLA_HUMAN Diacylglycerol lipase-alpha (sprot)

A diacylglycerol lipase-alpha that is encoded in the genome of human.


PLXD1_HUMAN Plexin-D1 (sprot)

A plexin-D1 that is encoded in the genome of human.


HECD4_HUMAN Probable E3 ubiquitin-protein ligase HECTD4 (sprot)

A probable E3 ubiquitin-protein ligase HECTD4 that is encoded in the genome of human.


WAC2C_HUMAN WASH complex subunit 2C (sprot)

A WASH complex subunit 2C that is encoded in the genome of human.


ZN451_HUMAN E3 SUMO-protein ligase ZNF451 (sprot)

An E3 SUMO-protein ligase ZNF451 that is encoded in the genome of human.


WDR7_HUMAN WD repeat-containing protein 7 (sprot)

A WD repeat-containing protein 7 that is encoded in the genome of human.


UBP15_HUMAN Ubiquitin carboxyl-terminal hydrolase 15 (sprot)

A ubiquitin carboxyl-terminal hydrolase 15 that is encoded in the genome of human.


FARP1_HUMAN FERM, ARHGEF and pleckstrin domain-containing protein 1 (sprot)

A FERM, ARHGEF and pleckstrin domain-containing protein 1 that is encoded in the genome of human.


MARF1_HUMAN Meiosis regulator and mRNA stability factor 1 (sprot)

A meiosis regulator and mRNA stability factor 1 that is encoded in the genome of human.


TGRM1_HUMAN TOG array regulator of axonemal microtubules protein 1 (sprot)

A TOG array regulator of axonemal microtubules protein 1 that is encoded in the genome of human.


C170B_HUMAN Centrosomal protein of 170 kDa protein B (sprot)

A centrosomal protein of 170 kDa protein B that is encoded in the genome of human.


RIPR2_HUMAN Rho family-interacting cell polarization regulator 2 (sprot)

A Rho family-interacting cell polarization regulator 2 that is encoded in the genome of human.


negative regulation of establishment of T cell polarity

Any process that stops, prevents or reduces the frequency, rate or extent of establishment of T cell polarity.


negative regulation of protein localization to cell leading edge

Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell leading edge.


negative regulation of Rho guanyl-nucleotide exchange factor activity

Any process that stops, prevents or reduces the frequency, rate or extent of Rho guanyl-nucleotide exchange factor activity.


PKHM1_HUMAN Pleckstrin homology domain-containing family M member 1 (sprot)

A pleckstrin homology domain-containing family M member 1 that is encoded in the genome of human.


TLN2_HUMAN Talin-2 (sprot)

A talin-2 that is encoded in the genome of human.


RPGF2_HUMAN Rap guanine nucleotide exchange factor 2 (sprot)

A Rap guanine nucleotide exchange factor 2 that is encoded in the genome of human.


IRS2_HUMAN Insulin receptor substrate 2 (sprot)

An insulin receptor substrate 2 that is encoded in the genome of human.


GPSM3_HUMAN G-protein-signaling modulator 3 (sprot)

A G-protein-signaling modulator 3 that is encoded in the genome of human.


MYO5A_HUMAN Unconventional myosin-Va (sprot)

A myosin-Va that is encoded in the genome of human.


MTL5_HUMAN Tesmin (sprot)

A tesmin that is encoded in the genome of human.


DTNA_HUMAN Dystrobrevin alpha (sprot)

A dystrobrevin alpha that is encoded in the genome of human.


LOXL2_HUMAN Lysyl oxidase homolog 2 (sprot)

A lysyl oxidase homolog 2 that is encoded in the genome of human.


CRBG1_HUMAN Beta/gamma crystallin domain-containing protein 1 (sprot)

A beta/gamma crystallin domain-containing protein 1 that is encoded in the genome of human.


TRAF6_HUMAN TNF receptor-associated factor 6 (sprot)

A TNF receptor-associated factor 6 that is encoded in the genome of human.


M4K5_HUMAN Mitogen-activated protein kinase kinase kinase kinase 5 (sprot)

A mitogen-activated protein kinase kinase kinase kinase 5 that is encoded in the genome of human.


HYOU1_HUMAN Hypoxia up-regulated protein 1 (sprot)

A hypoxia up-regulated protein 1 that is encoded in the genome of human.


RN115_HUMAN E3 ubiquitin-protein ligase RNF115 (sprot)

An E3 ubiquitin-protein ligase RNF115 that is encoded in the genome of human.


CH071_HUMAN Putative uncharacterized protein encoded by LINC00588 (sprot)


ATG4B_HUMAN Cysteine protease ATG4B (sprot)

A cysteine protease ATG4B that is encoded in the genome of human.


otolith mineralization completed early in development

The formation of otoliths during embryogenesis with completion in early postembryonic development. Formation occurs by precipitation of specific crystal forms of calcium carbonate around an organic core of extracellular matrix proteins. Otoconia (otoliths) are small (~10 micron) dense extracellular particles present in the otolith end organs of the vertebrate inner ear.


TBL2_HUMAN Transducin beta-like protein 2 (sprot)

A transducin beta-like protein 2 that is encoded in the genome of human.


WIPI2_HUMAN WD repeat domain phosphoinositide-interacting protein 2 (sprot)

A WD repeat domain phosphoinositide-interacting protein 2 that is encoded in the genome of human.


SPEF1_HUMAN Sperm flagellar protein 1 (sprot)

A sperm flagellar protein 1 that is encoded in the genome of human.


TTLL3_HUMAN Tubulin monoglycylase TTLL3 (sprot)

A tubulin monoglycylase TTLL3 that is encoded in the genome of human.


TELO2_HUMAN Telomere length regulation protein TEL2 homolog (sprot)

A telomere length regulation protein TEL2 that is encoded in the genome of human.


MMAC_HUMAN Cyanocobalamin reductase / alkylcobalamin dealkylase (sprot)

A cyanocobalamin reductase / alkylcobalamin dealkylase that is encoded in the genome of human.


cyanocobalamin reductase (cyanide-eliminating) activity

Catalysis of the reaction: cob(I)alamin + hydrogen cyanide + NADP+ = cyanocob(III)alamin + H+ + NADPH.


LAS1L_HUMAN Ribosomal biogenesis protein LAS1L (sprot)

A LAS1-like protein that is encoded in the genome of human.


Las1 complex

A four subunit complex, that comprises all the necessary RNA processing enzymes (endonuclease, polynucleotide kinase, and exonuclease) to mediate 'cistronic rRNA transcript ITS2 (internal transcribed spacer) cleavage' (GO:0000448).


AFG32_HUMAN AFG3-like protein 2 (sprot)

An AFG3-like protein 2 that is encoded in the genome of human.


AMMR1_HUMAN Nuclear protein AMMECR1 (sprot)

A nuclear protein AMMECR1 that is encoded in the genome of human.


CCL27_HUMAN C-C motif chemokine 27 (sprot)

A C-C motif chemokine 27 that is encoded in the genome of human.


KLF12_HUMAN Krueppel-like factor 12 (sprot)

A krueppel-like factor 12 that is encoded in the genome of human.


ARI1_HUMAN E3 ubiquitin-protein ligase ARIH1 (sprot)

An E3 ubiquitin-protein ligase ARIH1 that is encoded in the genome of human.


LSM5_HUMAN U6 snRNA-associated Sm-like protein LSm5 (sprot)

A U6 snRNA-associated Sm-like protein LSm5 that is encoded in the genome of human.


LSM4_HUMAN U6 snRNA-associated Sm-like protein LSm4 (sprot)

A U6 snRNA-associated Sm-like protein LSm4 that is encoded in the genome of human.


NGN3_HUMAN Neurogenin-3 (sprot)

A neurogenin-3 that is encoded in the genome of human.


RN114_HUMAN E3 ubiquitin-protein ligase RNF114 (sprot)

An E3 ubiquitin-protein ligase RNF114 that is encoded in the genome of human.


SAM50_HUMAN Sorting and assembly machinery component 50 homolog (sprot)

A sorting and assembly machinery component 50 that is encoded in the genome of human.


T184B_HUMAN Transmembrane protein 184B (sprot)

A transmembrane protein 184B that is encoded in the genome of human.


PRC2C_HUMAN Protein PRRC2C (sprot)

A protein PRRC2C that is encoded in the genome of human.


OARD1_HUMAN ADP-ribose glycohydrolase OARD1 (sprot)

An ADP-ribose glycohydrolase OARD1 that is encoded in the genome of human.


CSDC2_HUMAN Cold shock domain-containing protein C2 (sprot)

A cold shock domain-containing protein C2 that is encoded in the genome of human.


RPC8_HUMAN DNA-directed RNA polymerase III subunit RPC8 (sprot)

A DNA-directed RNA polymerase III subunit RPC8 that is encoded in the genome of human.


PAL4A_HUMAN Peptidyl-prolyl cis-trans isomerase A-like 4A (sprot)

A protein that is a translation product of the PPIAL4A gene in human.


HES2_HUMAN Transcription factor HES-2 (sprot)

A transcription factor HES-2 that is encoded in the genome of human.


IFT25_HUMAN Intraflagellar transport protein 25 homolog (sprot)

An intraflagellar transport protein 25 homolog that is encoded in the genome of human.


YIPF1_HUMAN Protein YIPF1 (sprot)

A protein YIPF1 that is encoded in the genome of human.


LRP12_HUMAN Low-density lipoprotein receptor-related protein 12 (sprot)

A low-density lipoprotein receptor-related protein 12 that is encoded in the genome of human.


SHAN1_HUMAN SH3 and multiple ankyrin repeat domains protein 1 (sprot)

An SH3 and multiple ankyrin repeat domains protein 1 that is encoded in the genome of human.


somatostatin receptor binding

Binding to a somatostatin receptor.


determination of affect

Any process in which an emotional response is associated with a particular sensory stimulation.


PPME1_HUMAN Protein phosphatase methylesterase 1 (sprot)

A protein phosphatase methylesterase 1 that is encoded in the genome of human.


protein C-terminal methylesterase activity

Catalysis of the reaction: C-terminal protein amino acid methyl ester + H2O = protein amino acid + methanol.


RIPK3_HUMAN Receptor-interacting serine/threonine-protein kinase 3 (sprot)

A receptor-interacting serine/threonine-protein kinase 3 that is encoded in the genome of human.


regulation of activation-induced cell death of T cells

Any process that modulates the occurrence or rate of activation-induced cell death of T cells.


regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation

Any process that modulates the frequency, rate or extent of CD8-positive, alpha-beta cytotoxic T cell extravasation.


IPP_HUMAN Actin-binding protein IPP (sprot)

An actin-binding protein IPP that is encoded in the genome of human.


ASB4_HUMAN Ankyrin repeat and SOCS box protein 4 (sprot)

An ankyrin repeat and SOCS box protein 4 that is encoded in the genome of human.


ASB3_HUMAN Ankyrin repeat and SOCS box protein 3 (sprot)

An ankyrin repeat and SOCS box protein 3 that is encoded in the genome of human.


ASB1_HUMAN Ankyrin repeat and SOCS box protein 1 (sprot)

An ankyrin repeat and SOCS box protein 1 that is encoded in the genome of human.


TRI17_HUMAN E3 ubiquitin-protein ligase TRIM17 (sprot)

An E3 ubiquitin-protein ligase TRIM17 that is encoded in the genome of human.


RBM7_HUMAN RNA-binding protein 7 (sprot)

An RNA-binding protein 7 that is encoded in the genome of human.


INSL6_HUMAN Insulin-like peptide INSL6 (sprot)

An insulin-like peptide INSL6 that is encoded in the genome of human.


TIM22_HUMAN Mitochondrial import inner membrane translocase subunit Tim22 (sprot)

A mitochondrial import inner membrane translocase subunit Tim22 that is encoded in the genome of human.


OR1A2_HUMAN Olfactory receptor 1A2 (sprot)

An olfactory receptor 1A2 that is encoded in the genome of human.


MB212_HUMAN Protein mab-21-like 2 (sprot)

A protein mab-21-like 2 that is encoded in the genome of human.


AP4S1_HUMAN AP-4 complex subunit sigma-1 (sprot)

An AP-4 complex subunit sigma-1 that is encoded in the genome of human.


CEP83_HUMAN Centrosomal protein of 83 kDa (sprot)

A centrosomal protein of 83 kDa that is encoded in the genome of human.


KCTD3_HUMAN BTB/POZ domain-containing protein KCTD3 (sprot)

A BTB/POZ domain-containing protein KCTD3 that is encoded in the genome of human.


ZSC21_HUMAN Zinc finger and SCAN domain-containing protein 21 (sprot)

A zinc finger and SCAN domain-containing protein 21 that is encoded in the genome of human.


NUB1_HUMAN NEDD8 ultimate buster 1 (sprot)

A NEDD8 ultimate buster 1 that is encoded in the genome of human.


YTHD2_HUMAN YTH domain-containing family protein 2 (sprot)

A YTH domain-containing family protein 2 that is encoded in the genome of human.


CTDP1_HUMAN RNA polymerase II subunit A C-terminal domain phosphatase (sprot)

An RNA polymerase II subunit A C-terminal domain phosphatase that is encoded in the genome of human.


TFIIF-class transcription factor complex binding

Binding to a general RNA polymerase II transcription factor belonging to the TFIIF complex, one of the factors involved in formation of the preinitiation complex (PIC) by RNA polymerase II.


PAXB1_HUMAN PAX3- and PAX7-binding protein 1 (sprot)

A PAX3- and PAX7-binding protein 1 that is encoded in the genome of human.


NDK7_HUMAN Nucleoside diphosphate kinase 7 (sprot)

A nucleoside diphosphate kinase 7 that is encoded in the genome of human.


SP16H_HUMAN FACT complex subunit SPT16 (sprot)

A FACT complex subunit SPT16 that is encoded in the genome of human.


ANGL3_HUMAN Angiopoietin-related protein 3 (sprot)

An angiopoietin-related protein 3 that is encoded in the genome of human.


PCDB9_HUMAN Protocadherin beta-9 (sprot)

A protocadherin beta-9 that is encoded in the genome of human.


PCDB7_HUMAN Protocadherin beta-7 (sprot)

A protocadherin beta-7 that is encoded in the genome of human.


PCDB6_HUMAN Protocadherin beta-6 (sprot)

A protocadherin beta-6 that is encoded in the genome of human.


PCDB5_HUMAN Protocadherin beta-5 (sprot)

A protocadherin beta-5 that is encoded in the genome of human.


PCDB4_HUMAN Protocadherin beta-4 (sprot)

A protocadherin beta-4 that is encoded in the genome of human.


PCDB3_HUMAN Protocadherin beta-3 (sprot)

A protocadherin beta-3 that is encoded in the genome of human.


PCDB2_HUMAN Protocadherin beta-2 (sprot)

A protocadherin beta-2 that is encoded in the genome of human.


PCDBF_HUMAN Protocadherin beta-15 (sprot)

A protocadherin beta-15 that is encoded in the genome of human.


PCDBE_HUMAN Protocadherin beta-14 (sprot)

A protocadherin beta-14 that is encoded in the genome of human.


PCDBD_HUMAN Protocadherin beta-13 (sprot)

A protocadherin beta-13 that is encoded in the genome of human.


PCDBC_HUMAN Protocadherin beta-12 (sprot)

A protocadherin beta-12 that is encoded in the genome of human.


PCDBB_HUMAN Protocadherin beta-11 (sprot)

A protocadherin beta-11 that is encoded in the genome of human.


PCDB1_HUMAN Protocadherin beta-1 (sprot)

A protocadherin beta-1 that is encoded in the genome of human.


PCDGM_HUMAN Protocadherin gamma-C5 (sprot)

A protocadherin gamma-C5 that is encoded in the genome of human.


PCDGL_HUMAN Protocadherin gamma-C4 (sprot)

A protocadherin gamma-C4 that is encoded in the genome of human.


PCDGJ_HUMAN Protocadherin gamma-B7 (sprot)

A protocadherin gamma-B7 that is encoded in the genome of human.


PCDGI_HUMAN Protocadherin gamma-B6 (sprot)

A protocadherin gamma-B6 that is encoded in the genome of human.


PCDGH_HUMAN Protocadherin gamma-B5 (sprot)

A protocadherin gamma-B5 that is encoded in the genome of human.


PCDGF_HUMAN Protocadherin gamma-B3 (sprot)

A protocadherin gamma-B3 that is encoded in the genome of human.


PCDGE_HUMAN Protocadherin gamma-B2 (sprot)

A protocadherin gamma-B2 that is encoded in the genome of human.


PCDGD_HUMAN Protocadherin gamma-B1 (sprot)

A protocadherin gamma-B1 that is encoded in the genome of human.


PCDG9_HUMAN Protocadherin gamma-A9 (sprot)

A protocadherin gamma-A9 that is encoded in the genome of human.


PCDG8_HUMAN Protocadherin gamma-A8 (sprot)

A protocadherin gamma-A8 that is encoded in the genome of human.


PCDG7_HUMAN Protocadherin gamma-A7 (sprot)

A protocadherin gamma-A7 that is encoded in the genome of human.


PCDG6_HUMAN Protocadherin gamma-A6 (sprot)

A protocadherin gamma-A6 that is encoded in the genome of human.


PCDG5_HUMAN Protocadherin gamma-A5 (sprot)

A protocadherin gamma-A5 that is encoded in the genome of human.


PCDG4_HUMAN Protocadherin gamma-A4 (sprot)

A protocadherin gamma-A4 that is encoded in the genome of human.


PCDG3_HUMAN Protocadherin gamma-A3 (sprot)

A protocadherin gamma-A3 that is encoded in the genome of human.


lipid tube assembly involved in organelle fusion

The aggregation, arrangement and bonding together of a set of macromolecules to form a macromolecular complex that contains a tube of lipid surrounded by a protein coat involved in membrane shaping of vesicle membranes as organelles fuse.


PCDG2_HUMAN Protocadherin gamma-A2 (sprot)

A protocadherin gamma-A2 that is encoded in the genome of human.


PCDGB_HUMAN Protocadherin gamma-A11 (sprot)

A protocadherin gamma-A11 that is encoded in the genome of human.


PCDGA_HUMAN Protocadherin gamma-A10 (sprot)

A protocadherin gamma-A10 that is encoded in the genome of human.


PCDG1_HUMAN Protocadherin gamma-A1 (sprot)

A protocadherin gamma-A1 that is encoded in the genome of human.


PCDA9_HUMAN Protocadherin alpha-9 (sprot)

A protocadherin alpha-9 that is encoded in the genome of human.


PCDA8_HUMAN Protocadherin alpha-8 (sprot)

A protocadherin alpha-8 that is encoded in the genome of human.


PCDA5_HUMAN Protocadherin alpha-5 (sprot)

A protocadherin alpha-5 that is encoded in the genome of human.


PCDA3_HUMAN Protocadherin alpha-3 (sprot)

A protocadherin alpha-3 that is encoded in the genome of human.


PCDA2_HUMAN Protocadherin alpha-2 (sprot)

A protocadherin alpha-2 that is encoded in the genome of human.


PCDAD_HUMAN Protocadherin alpha-13 (sprot)

A protocadherin alpha-13 that is encoded in the genome of human.


PCDAB_HUMAN Protocadherin alpha-11 (sprot)

A protocadherin alpha-11 that is encoded in the genome of human.


PCDAA_HUMAN Protocadherin alpha-10 (sprot)

A protocadherin alpha-10 that is encoded in the genome of human.


PCDA1_HUMAN Protocadherin alpha-1 (sprot)

A protocadherin alpha-1 that is encoded in the genome of human.


PCDC2_HUMAN Protocadherin alpha-C2 (sprot)

A protocadherin alpha-C2 that is encoded in the genome of human.


CLD16_HUMAN Claudin-16 (sprot)

A claudin-16 that is encoded in the genome of human.


intercellular transport

The movement of substances between cells.


UTP18_HUMAN U3 small nucleolar RNA-associated protein 18 homolog (sprot)

A U3 small nucleolar RNA-associated protein 18 that is encoded in the genome of human.


HEY1_HUMAN Hairy/enhancer-of-split related with YRPW motif protein 1 (sprot)

A hairy/enhancer-of-split related with YRPW motif protein 1 that is encoded in the genome of human.


PHLA3_HUMAN Pleckstrin homology-like domain family A member 3 (sprot)

A pleckstrin homology-like domain family A member 3 that is encoded in the genome of human.


T10B_HUMAN Mitochondrial import inner membrane translocase subunit Tim10 B (sprot)

A mitochondrial import inner membrane translocase subunit Tim9 B that is encoded in the genome of human.


TIM9_HUMAN Mitochondrial import inner membrane translocase subunit Tim9 (sprot)

A mitochondrial import inner membrane translocase subunit Tim9 that is encoded in the genome of human.


TIM8B_HUMAN Mitochondrial import inner membrane translocase subunit Tim8 B (sprot)

A mitochondrial import inner membrane translocase subunit Tim8 B that is encoded in the genome of human.


SPO11_HUMAN Meiotic recombination protein SPO11 (sprot)

A meiotic recombination protein SPO11 that is encoded in the genome of human.


KLK4_HUMAN Kallikrein-4 (sprot)

A kallikrein-4 that is encoded in the genome of human.


PCY1B_HUMAN Choline-phosphate cytidylyltransferase B (sprot)

A choline-phosphate cytidylyltransferase B that is encoded in the genome of human.


UCHL5_HUMAN Ubiquitin carboxyl-terminal hydrolase isozyme L5 (sprot)

A ubiquitin carboxyl-terminal hydrolase isozyme L5 that is encoded in the genome of human.


CD2AP_HUMAN CD2-associated protein (sprot)

A CD2-associated protein that is encoded in the genome of human.


VATD_HUMAN V-type proton ATPase subunit D (sprot)

A V-type proton ATPase subunit D that is encoded in the genome of human.


TNPO3_HUMAN Transportin-3 (sprot)

A transportin-3 that is encoded in the genome of human.


HLPDA_HUMAN Hypoxia-inducible lipid droplet-associated protein (sprot)

A hypoxia-inducible lipid droplet-associated protein that is encoded in the genome of human.


ENTP2_HUMAN Ectonucleoside triphosphate diphosphohydrolase 2 (sprot)

An ectonucleoside triphosphate diphosphohydrolase 2 that is encoded in the genome of human.


purine ribonucleoside diphosphate catabolic process

The chemical reactions and pathways resulting in the breakdown of purine ribonucleoside diphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with diphosphate on the sugar.


TIM13_HUMAN Mitochondrial import inner membrane translocase subunit Tim13 (sprot)

A mitochondrial import inner membrane translocase subunit Tim13 that is encoded in the genome of human.


LENEP_HUMAN Lens epithelial cell protein LEP503 (sprot)

A lens epithelial cell protein LEP503 that is encoded in the genome of human.


F215A_HUMAN Uncharacterized protein FAM215A (sprot)

An apoptosis-related protein 2 that is encoded in the genome of human.


SRPRB_HUMAN Signal recognition particle receptor subunit beta (sprot)

A signal recognition particle receptor subunit beta that is encoded in the genome of human.


HRH3_HUMAN Histamine H3 receptor (sprot)

A histamine H3 receptor that is encoded in the genome of human.


N6MT1_HUMAN Methyltransferase N6AMT1 (sprot)

A methyltransferase N6AMT1 that is encoded in the genome of human.


Catalysis of the reaction: S-adenosyl-L-methionine + protein L-glutamine = S-adenosyl-L-homocysteine + protein N-methyl-L-glutamine.


histone H4K12 methyltransferase activity

Catalysis of the reaction: S-adenosyl-L-methionine + histone H4 L-lysine (position 12) = S-adenosyl-L-homocysteine + histone H4 N6-methyl-L-lysine (position 12). This reaction is the addition of a methyl group to the lysine residue at position 12 of the histone H4 protein.


ORC6_HUMAN Origin recognition complex subunit 6 (sprot)

An origin recognition complex subunit 6 that is encoded in the genome of human.


O51B4_HUMAN Olfactory receptor 51B4 (sprot)

An olfactory receptor 51B4 that is encoded in the genome of human.


O51B2_HUMAN Olfactory receptor 51B2 (sprot)

An olfactory receptor 51B2 that is encoded in the genome of human.


CSAG2_HUMAN Chondrosarcoma-associated gene 2/3 protein (sprot)

A chondrosarcoma-associated gene 2/3A protein that is encoded in the genome of human.


RAI2_HUMAN Retinoic acid-induced protein 2 (sprot)

A retinoic acid-induced protein 2 that is encoded in the genome of human.


CERT_HUMAN Ceramide transfer protein (sprot)

A ceramide transfer protein that is encoded in the genome of human.


ceramide transfer activity

Removes a ceramide from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle.


intermembrane sphingolipid transfer

The transport of sphingolipids between membranes in which a sphingolipid molecule is transported through an aqueous phase from the outer leaflet of a donor membrane to the outer leaflet of an acceptor membrane. This process does not require metabolic energy and can be either spontaneous or mediated by lipid transfer proteins (LTPs).


GMPPB_HUMAN Mannose-1-phosphate guanyltransferase beta (sprot)

A mannose-1-phosphate guanyltransferase beta that is encoded in the genome of human.


P2R3B_HUMAN Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta (sprot)

A serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta that is encoded in the genome of human.


FADS3_HUMAN Fatty acid desaturase 3 (sprot)

A fatty acid desaturase 3 that is encoded in the genome of human.


MAFB_HUMAN Transcription factor MafB (sprot)

A transcription factor MafB that is encoded in the genome of human.


rhombomere 6 development

The process whose specific outcome is the progression of rhombomere 6 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.


CORIN_HUMAN Atrial natriuretic peptide-converting enzyme (sprot)

An atrial natriuretic peptide-converting enzyme that is encoded in the genome of human.


INSL5_HUMAN Insulin-like peptide INSL5 (sprot)

An insulin-like peptide INSL5 that is encoded in the genome of human.


TF3C5_HUMAN General transcription factor 3C polypeptide 5 (sprot)

A general transcription factor 3C polypeptide 5 that is encoded in the genome of human.


TF3C3_HUMAN General transcription factor 3C polypeptide 3 (sprot)

A general transcription factor 3C polypeptide 3 that is encoded in the genome of human.


MMP24_HUMAN Matrix metalloproteinase-24 (sprot)

A matrix metalloproteinase-24 that is encoded in the genome of human.


HEMK1_HUMAN MTRF1L release factor glutamine methyltransferase (sprot)

An MTRF1L release factor glutamine methyltransferase that is encoded in the genome of human.


Catalysis of the reaction: S-adenosyl-L-methionine + a [release factor]-L-glutamine = S-adenosyl-L-homocysteine + H+ + a [release factor]-N5-methyl-L-glutamine.


DMRT2_HUMAN Doublesex- and mab-3-related transcription factor 2 (sprot)

A doublesex- and mab-3-related transcription factor 2 that is encoded in the genome of human.


positive regulation of myotome development

Any process that activates or increases the frequency, rate or extent of myotome development.


DMRT1_HUMAN Doublesex- and mab-3-related transcription factor 1 (sprot)

A doublesex- and mab-3-related transcription factor 1 that is encoded in the genome of human.


TPPC1_HUMAN Trafficking protein particle complex subunit 1 (sprot)

A trafficking protein particle complex subunit 1 that is encoded in the genome of human.


TRPV2_HUMAN Transient receptor potential cation channel subfamily V member 2 (sprot)

A transient receptor potential cation channel TRPV2 that is encoded in the genome of human.


MRCKB_HUMAN Serine/threonine-protein kinase MRCK beta (sprot)

A serine/threonine-protein kinase MRCK beta that is encoded in the genome of human.


NOX1_HUMAN NADPH oxidase 1 (sprot)

An NADPH oxidase 1 that is encoded in the genome of human.


cellular stress response to acidic pH

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in the homeostasis of organismal or cellular pH (with pH < 7). pH is a measure of the acidity or basicity of an aqueous solution.


RBM8A_HUMAN RNA-binding protein 8A (sprot)

An RNA-binding protein 8A that is encoded in the genome of human.


DJC15_HUMAN DnaJ homolog subfamily C member 15 (sprot)

A DnaJ homolog subfamily C member 15 that is encoded in the genome of human.


UBP16_HUMAN Ubiquitin carboxyl-terminal hydrolase 16 (sprot)

A ubiquitin carboxyl-terminal hydrolase 16 that is encoded in the genome of human.


positive regulation of ribosome biogenesis

Any process that increases the rate, frequency or extent of ribosome biogenesis. Ribosome biogenesis is the cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits.


TSSC4_HUMAN U5 small nuclear ribonucleoprotein TSSC4 (sprot)

A protein TSSC4 that is encoded in the genome of human.


INSI2_HUMAN Insulin-induced gene 2 protein (sprot)

An insulin-induced gene 2 protein that is encoded in the genome of human.


TNR18_HUMAN Tumor necrosis factor receptor superfamily member 18 (sprot)

A tumor necrosis factor receptor superfamily member 18 that is encoded in the genome of human.


MPC1_HUMAN Mitochondrial pyruvate carrier 1 (sprot)

A brain protein 44-like protein that is encoded in the genome of human.


IR3IP_HUMAN Immediate early response 3-interacting protein 1 (sprot)

An immediate early response 3-interacting protein 1 that is encoded in the genome of human.


ZN706_HUMAN Zinc finger protein 706 (sprot)

A zinc finger protein 706 that is encoded in the genome of human.


MAGD1_HUMAN Melanoma-associated antigen D1 (sprot)

A melanoma-associated antigen D1 that is encoded in the genome of human.


KLF2_HUMAN Krueppel-like factor 2 (sprot)

A krueppel-like factor 2 that is encoded in the genome of human.


WIF1_HUMAN Wnt inhibitory factor 1 (sprot)

A Wnt inhibitory factor 1 that is encoded in the genome of human.


SNX14_HUMAN Sorting nexin-14 (sprot)

A sorting nexin-14 that is encoded in the genome of human.


SNX13_HUMAN Sorting nexin-13 (sprot)

A sorting nexin-13 that is encoded in the genome of human.


SNX11_HUMAN Sorting nexin-11 (sprot)

A sorting nexin-11 that is encoded in the genome of human.


SNX10_HUMAN Sorting nexin-10 (sprot)

A sorting nexin-10 that is encoded in the genome of human.


extrinsic component of endosome membrane

The component of an endosome membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.


SNX9_HUMAN Sorting nexin-9 (sprot)

A sorting nexin-9 that is encoded in the genome of human.


SNX8_HUMAN Sorting nexin-8 (sprot)

A sorting nexin-8 that is encoded in the genome of human.


SNX5_HUMAN Sorting nexin-5 (sprot)

A sorting nexin-5 that is encoded in the genome of human.


macropinocytic cup

A cell projection that forms at the site of macropinocytosis, a form of endocytosis that results in the uptake of relatively large amounts of extracellular fluid. The macropinocytic cup membrane selectively excludes certain proteins, such as H36 or PM4C4 in Dictyostelium, and the underlying cytoskeleton is enriched in F-actin and coronin.


NR2E3_HUMAN Photoreceptor-specific nuclear receptor (sprot)

A photoreceptor-specific nuclear receptor that is encoded in the genome of human.


NPFF2_HUMAN Neuropeptide FF receptor 2 (sprot)

A neuropeptide FF receptor 2 that is encoded in the genome of human.


opioid receptor binding

Binding to an opioid receptor.


LIPG_HUMAN Endothelial lipase (sprot)

An endothelial lipase that is encoded in the genome of human.


FLVC1_HUMAN Heme transporter FLVCR1 (sprot)

A feline leukemia virus subgroup C receptor-related protein 1 that is encoded in the genome of human.


NUBP2_HUMAN Cytosolic Fe-S cluster assembly factor NUBP2 (sprot)

A cytosolic Fe-S cluster assembly factor NUBP2 that is encoded in the genome of human.


GPR45_HUMAN Probable G-protein coupled receptor 45 (sprot)

A probable G-protein coupled receptor 45 that is encoded in the genome of human.


PD2R2_HUMAN Prostaglandin D2 receptor 2 (sprot)

A prostaglandin D2 receptor DP2 that is encoded in the genome of human.


PEX16_HUMAN Peroxisomal membrane protein PEX16 (sprot)

A peroxisomal membrane protein PEX16 that is encoded in the genome of human.


ER-dependent peroxisome organization

A process of peroxisome organization in which assembly or arrangement of constituent parts takes place in the endoplasmic reticulum.


ER-dependent peroxisome localization

A process in which a protein is transported to, or maintained at, a location in a peroxisome via the endoplasmic reticulum.


ST14_HUMAN Suppressor of tumorigenicity 14 protein (sprot)

A suppressor of tumorigenicity 14 protein that is encoded in the genome of human.


LYVE1_HUMAN Lymphatic vessel endothelial hyaluronic acid receptor 1 (sprot)

A lymphatic vessel endothelial hyaluronic acid receptor 1 that is encoded in the genome of human.


SCNAA_HUMAN Sodium channel protein type 10 subunit alpha (sprot)

A sodium channel protein type 10 subunit alpha that is encoded in the genome of human.


BACE2_HUMAN Beta-secretase 2 (sprot)

A beta-secretase 2 that is encoded in the genome of human.


HEBP2_HUMAN Heme-binding protein 2 (sprot)

A heme-binding protein 2 that is encoded in the genome of human.


B3GT1_HUMAN Beta-1,3-galactosyltransferase 1 (sprot)

A beta-1,3-galactosyltransferase 1 that is encoded in the genome of human.


HCFC2_HUMAN Host cell factor 2 (sprot)

A host cell factor 2 that is encoded in the genome of human.


immune response involved in response to exogenous dsRNA

Any immune response that is involved in response to exogenous dsRNA.


UBIA1_HUMAN UbiA prenyltransferase domain-containing protein 1 (sprot)

A UbiA prenyltransferase domain-containing protein 1 that is encoded in the genome of human.


menaquinone biosynthetic process

The chemical reactions and pathways resulting in the formation of any of the menaquinones. Structurally, menaquinones consist of a methylated naphthoquinone ring structure and side chains composed of a variable number of unsaturated isoprenoid residues. Menaquinones that have vitamin K activity and are known as vitamin K2.


vitamin K biosynthetic process

The chemical reactions and pathways resulting in the formation of any of the forms of vitamin K, quinone-derived vitamins which are involved in the synthesis of blood-clotting factors in mammals.


CSAD_HUMAN Cysteine sulfinic acid decarboxylase (sprot)

A cysteine sulfinic acid decarboxylase that is encoded in the genome of human.


L-cysteine catabolic process to hypotaurine

The chemical reactions and pathways resulting in the breakdown of L-cysteine into other compounds, including hypotaurine.


L-cysteine catabolic process to taurine

The chemical reactions and pathways resulting in the breakdown of L-cysteine into other compounds, including taurine.


ETV7_HUMAN Transcription factor ETV7 (sprot)

A transcription factor ETV7 that is encoded in the genome of human.


MOFA1_HUMAN MORF4 family-associated protein 1 (sprot)

A MORF4 family-associated protein 1 that is encoded in the genome of human.


PUS1_HUMAN Pseudouridylate synthase 1 homolog (sprot)

A eukaryotic tRNA pseudouridine synthase A that is encoded in the genome of human.


LRRF2_HUMAN Leucine-rich repeat flightless-interacting protein 2 (sprot)

A leucine-rich repeat flightless-interacting protein 2 that is encoded in the genome of human.


FHOD1_HUMAN FH1/FH2 domain-containing protein 1 (sprot)

An FH1/FH2 domain-containing protein 1 that is encoded in the genome of human.


ACL7B_HUMAN Actin-like protein 7B (sprot)

An actin-like protein 7B that is encoded in the genome of human.


ACL7A_HUMAN Actin-like protein 7A (sprot)

An actin-like protein 7A that is encoded in the genome of human.


IRAK3_HUMAN Interleukin-1 receptor-associated kinase 3 (sprot)

An interleukin-1 receptor-associated kinase 3 that is encoded in the genome of human.


positive regulation of macrophage tolerance induction

Any process that increases the frequency, rate, or extent of B cell tolerance induction.


regulation of protein-containing complex disassembly

Any process that modulates the frequency, rate or extent of protein complex disassembly, the disaggregation of a protein complex into its constituent components.


SERC_HUMAN Phosphoserine aminotransferase (sprot)

A phosphoserine aminotransferase that is encoded in the genome of human.


Catalysis of the reaction: O-phospho-L-serine + 2-oxoglutarate = 3-phosphonooxypyruvate + L-glutamate.


NCOR2_HUMAN Nuclear receptor corepressor 2 (sprot)

A nuclear receptor corepressor 2 that is encoded in the genome of human.


ORNT1_HUMAN Mitochondrial ornithine transporter 1 (sprot)

A mitochondrial ornithine transporter 1 that is encoded in the genome of human.


RA54B_HUMAN DNA repair and recombination protein RAD54B (sprot)

A DNA repair and recombination protein RAD54B that is encoded in the genome of human.


MYH4_HUMAN Myosin-4 (sprot)

A myosin-4 that is encoded in the genome of human.


JAM1_HUMAN Junctional adhesion molecule A (sprot)

A junctional adhesion molecule A that is encoded in the genome of human.


GPC6_HUMAN Glypican-6 (sprot)

A glypican-6 that is encoded in the genome of human.


NPTN_HUMAN Neuroplastin (sprot)

A neuroplastin that is encoded in the genome of human.


regulation of receptor localization to synapse

Any process that modulates the frequency, rate or extent of receptor localization to synapse.


RFNG_HUMAN Beta-1,3-N-acetylglucosaminyltransferase radical fringe (sprot)

A beta-1,3-N-acetylglucosaminyltransferase radical fringe that is encoded in the genome of human.


CBPQ_HUMAN Carboxypeptidase Q (sprot)

A carboxypeptidase Q that is encoded in the genome of human.


SOX21_HUMAN Transcription factor SOX-21 (sprot)

A transcription factor SOX-21 that is encoded in the genome of human.


AGRG1_HUMAN Adhesion G-protein coupled receptor G1 (sprot)

An adhesion G-protein coupled receptor G1 that is encoded in the genome of human.


SPIN1_HUMAN Spindlin-1 (sprot)

A spindlin-1 that is encoded in the genome of human.


HS3S4_HUMAN Heparan sulfate glucosamine 3-O-sulfotransferase 4 (sprot)

A heparan sulfate glucosamine 3-O-sulfotransferase 4 that is encoded in the genome of human.


HS3SB_HUMAN Heparan sulfate glucosamine 3-O-sulfotransferase 3B1 (sprot)

A heparan sulfate glucosamine 3-O-sulfotransferase 3B1 that is encoded in the genome of human.


[heparan sulfate]-glucosamine 3-sulfotransferase 3 activity

Catalysis of the reaction: 3'-phosphoadenylyl sulfate + [heparan sulfate]-glucosamine = adenosine 3',5'-bisphosphate + [heparan sulfate]-glucosamine 3-sulfate.


HS3SA_HUMAN Heparan sulfate glucosamine 3-O-sulfotransferase 3A1 (sprot)

A heparan sulfate glucosamine 3-O-sulfotransferase 3A1 that is encoded in the genome of human.


KPTN_HUMAN KICSTOR complex protein kaptin (sprot)

A KICSTOR complex protein kaptin that is encoded in the genome of human.


S12A7_HUMAN Solute carrier family 12 member 7 (sprot)

A solute carrier family 12 member 7 that is encoded in the genome of human.


ALG6_HUMAN Dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase (sprot)

A dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase that is encoded in the genome of human.


ALG5_HUMAN Dolichyl-phosphate beta-glucosyltransferase (sprot)

A dolichyl-phosphate beta-glucosyltransferase that is encoded in the genome of human.


oligosaccharyl transferase activity

Catalysis of the transfer of a oligosaccharyl group to an acceptor molecule, typically another carbohydrate or a lipid.


Catalysis of the reaction: UDP-glucose + dolichyl phosphate = UDP + dolichyl beta-D-glucosyl phosphate.


SNURF_HUMAN SNRPN upstream reading frame protein (sprot)

A SNRPN upstream reading frame protein that is encoded in the genome of human.


RT18B_HUMAN Small ribosomal subunit protein mS40 (sprot)

A 28S ribosomal protein S18b, mitochondrial that is encoded in the genome of human.


COPG1_HUMAN Coatomer subunit gamma-1 (sprot)

A coatomer subunit gamma-1 that is encoded in the genome of human.


AUP1_HUMAN Lipid droplet-regulating VLDL assembly factor AUP1 (sprot)

A lipid droplet-regulating VLDL assembly factor AUP1 that is encoded in the genome of human.


FKBP7_HUMAN Peptidyl-prolyl cis-trans isomerase FKBP7 (sprot)

A peptidyl-prolyl cis-trans isomerase FKBP7 that is encoded in the genome of human.


ARL5A_HUMAN ADP-ribosylation factor-like protein 5A (sprot)

An ADP-ribosylation factor-like protein 5A that is encoded in the genome of human.


KCMB2_HUMAN Calcium-activated potassium channel subunit beta-2 (sprot)

A calcium-activated potassium channel subunit beta-2 that is encoded in the genome of human.


GMEB1_HUMAN Glucocorticoid modulatory element-binding protein 1 (sprot)

A glucocorticoid modulatory element-binding protein 1 that is encoded in the genome of human.


Hsp27 protein binding

Binding to Hsp27 proteins, a lightweight heat shock protein.


S22A7_HUMAN Solute carrier family 22 member 7 (sprot)

A solute carrier family 22 member 7 that is encoded in the genome of human.


CLIC4_HUMAN Chloride intracellular channel protein 4 (sprot)

A chloride intracellular channel protein 4 that is encoded in the genome of human.


establishment or maintenance of apical/basal cell polarity

Any cellular process that results in the specification, formation or maintenance polarization of a cell's architecture along its apical/basal axis so that the apical and basal regions of the cell have different membrane, extracellular matrix and sub-membrane cellular components.


NFS1_HUMAN Cysteine desulfurase (sprot)

A cysteine desulfurase NFS1 that is encoded in the genome of human.


cysteine desulfurase activity

Catalysis of the reaction: L-cysteine + [enzyme]-cysteine = L-alanine + [enzyme]-S-sulfanylcysteine.


CCG2_HUMAN Voltage-dependent calcium channel gamma-2 subunit (sprot)

A voltage-dependent calcium channel gamma-2 subunit that is encoded in the genome of human.


eye blink reflex

The reflex process in which a mechanical stimulus applied to the eye elicits a response of the eyelid closing.


positive regulation of protein localization to basolateral plasma membrane

Any process that activates or increases the frequency, rate or extent of protein localization to basolateral plasma membrane.


POMT1_HUMAN Protein O-mannosyl-transferase 1 (sprot)

A protein O-mannosyl-transferase 1 that is encoded in the genome of human.


CP46A_HUMAN Cholesterol 24-hydroxylase (sprot)

A cytochrome P450 46A1 that is encoded in the genome of human.


cholesterol 24-hydroxylase activity

Catalysis of the reaction: cholesterol + H+ + NADPH + O2 = (24S)-24-hydroxycholesterol + H2O + NADP+.


CFA20_HUMAN Cilia- and flagella-associated protein 20 (sprot)

A cilia- and flagella-associated protein 20 that is encoded in the genome of human.


TACC3_HUMAN Transforming acidic coiled-coil-containing protein 3 (sprot)

A transforming acidic coiled-coil-containing protein 3 that is encoded in the genome of human.


SPCS1_HUMAN Signal peptidase complex subunit 1 (sprot)

A signal peptidase complex subunit 1 that is encoded in the genome of human.


EID1_HUMAN EP300-interacting inhibitor of differentiation 1 (sprot)

An EP300-interacting inhibitor of differentiation 1 that is encoded in the genome of human.


SAR1B_HUMAN GTP-binding protein SAR1b (sprot)

A GTP-binding protein SAR1b that is encoded in the genome of human.


AP4B1_HUMAN AP-4 complex subunit beta-1 (sprot)

An AP-4 complex subunit beta-1 that is encoded in the genome of human.


protein localization to somatodendritic compartment

A process in which a protein is transported to or maintained in a location within the somatodendritic compartment.


cytoplasmic side of trans-Golgi network transport vesicle membrane

The side (leaflet) of the trans-Golgi network transport vesicle membrane that faces the cytoplasm.


EMIL1_HUMAN EMILIN-1 (sprot)

An EMILIN-1 that is encoded in the genome of human.


PTC2_HUMAN Protein patched homolog 2 (sprot)

A protein patched homolog 2 that is encoded in the genome of human.


MTCH2_HUMAN Mitochondrial carrier homolog 2 (sprot)

A mitochondrial carrier homolog 2 that is encoded in the genome of human.


SELK_HUMAN Selenoprotein K (sprot)

A selenoprotein K that is encoded in the genome of human.


BIG2_HUMAN Brefeldin A-inhibited guanine nucleotide-exchange protein 2 (sprot)

A brefeldin A-inhibited guanine nucleotide-exchange protein 2 that is encoded in the genome of human.


endomembrane system organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endomembrane system.


BIG1_HUMAN Brefeldin A-inhibited guanine nucleotide-exchange protein 1 (sprot)

A brefeldin A-inhibited guanine nucleotide-exchange protein 1 that is encoded in the genome of human.


MD1L1_HUMAN Mitotic spindle assembly checkpoint protein MAD1 (sprot)

A mitotic spindle assembly checkpoint protein MAD1 that is encoded in the genome of human.


MAD1 complex

A protein complex involved in the assembly of the mitotic checkpoint complex that in turn inhibits the anaphase promoting complex/cyclosome (APC/C).


STK24_HUMAN Serine/threonine-protein kinase 24 (sprot)

A serine/threonine-protein kinase 24 that is encoded in the genome of human.


5MP1_HUMAN eIF5-mimic protein 1 (sprot)

An eIF5-mimic protein 1 that is encoded in the genome of human.


SIR4_HUMAN NAD-dependent protein lipoamidase sirtuin-4, mitochondrial (sprot)

An NAD-dependent protein lipoamidase sirtuin-4, mitochondrial that is encoded in the genome of human.


lipoamidase activity

Catalysis of the cleavage of the amide bond to release lipoic acid from a lipoylated protein.


NAD-dependent protein lipoamidase activity

Catalysis of the reaction: (R)-N6-lipoyl-L-lysyl-[protein] + H2O + NAD+ = 2''-O-lipoyl-ADP-D-ribose + L-lysyl-[protein] + nicotinamide.


NAD-dependent protein biotinidase activity

Catalysis of the reaction: H2O + N6-biotinyl-L-lysyl-[protein] + NAD+ = 2''-O-biotinyl-ADP-D-ribose + L-lysyl-[protein] + nicotinamide.


regulation of glutamine family amino acid metabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving amino acids of the glutamine family, comprising arginine, glutamate, glutamine and proline.


regulation of pyruvate dehydrogenase activity

Any process that modulates the frequency, rate or extent of pyruvate dehydrogenase activity.


PARP3_HUMAN Protein mono-ADP-ribosyltransferase PARP3 (sprot)

A protein mono-ADP-ribosyltransferase PARP3 that is encoded in the genome of human.


negative regulation of isotype switching

Any process that stops, prevents, or reduces the frequency, rate or extent of isotype switching.


negative regulation of telomerase RNA reverse transcriptase activity

Any process that stops, prevents or reduces the frequency, rate or extent of telomerase RNA reverse transcriptase activity.


IRAG1_HUMAN Inositol 1,4,5-triphosphate receptor associated 1 (sprot)

An inositol 1,4,5-triphosphate receptor associated 1 that is encoded in the genome of human.


CDY2_HUMAN Testis-specific chromodomain protein Y 2 (sprot)

A testis-specific chromodomain protein Y 2 that is encoded in the genome of human.


CDY1_HUMAN Testis-specific chromodomain protein Y 1 (sprot)

A testis-specific chromodomain protein Y 1 that is encoded in the genome of human.


WNT6_HUMAN Protein Wnt-6 (sprot)

A protein Wnt-6 that is encoded in the genome of human.


axis specification

The establishment, maintenance and elaboration of a pattern along a line or around a point.


TM14A_HUMAN Transmembrane protein 14A (sprot)

A transmembrane protein 14A that is encoded in the genome of human.


RM42_HUMAN Large ribosomal subunit protein mL42 (sprot)

A 28S ribosomal protein L42, mitochondrial that is encoded in the genome of human.


COMDA_HUMAN COMM domain-containing protein 10 (sprot)

A COMM domain-containing protein 10 that is encoded in the genome of human.


DC1L1_HUMAN Cytoplasmic dynein 1 light intermediate chain 1 (sprot)

A cytoplasmic dynein 1 light intermediate chain 1 that is encoded in the genome of human.


CHCH2_HUMAN Coiled-coil-helix-coiled-coil-helix domain-containing protein 2 (sprot)

A coiled-coil-helix-coiled-coil-helix domain-containing protein 2 that is encoded in the genome of human.


ATP23_HUMAN Mitochondrial inner membrane protease ATP23 homolog (sprot)

A mitochondrial inner membrane protease ATP23 that is encoded in the genome of human.


SNCAP_HUMAN Synphilin-1 (sprot)

A synphilin-1 that is encoded in the genome of human.


KCNE3_HUMAN Potassium voltage-gated channel subfamily E member 3 (sprot)

A potassium voltage-gated channel subfamily E member 3 that is encoded in the genome of human.


negative regulation of membrane repolarization during ventricular cardiac muscle cell action potential

Any process that stops, prevents or reduces the frequency, rate or extent of membrane repolarization during ventricular cardiac muscle cell action potential.


CXA3_HUMAN Gap junction alpha-3 protein (sprot)

A gap junction alpha-3 protein that is encoded in the genome of human.


EPN1_HUMAN Epsin-1 (sprot)

An epsin-1 that is encoded in the genome of human.


UBP3_HUMAN Ubiquitin carboxyl-terminal hydrolase 3 (sprot)

A ubiquitin carboxyl-terminal hydrolase 3 that is encoded in the genome of human.


WSB1_HUMAN WD repeat and SOCS box-containing protein 1 (sprot)

A WD repeat and SOCS box-containing protein 1 that is encoded in the genome of human.


protein aggregate center assembly

The reversible aggregation of misfolded proteins and chaperones, formed to shield thermosensitive proteins from degradation until conditions allow disaggregation and refolding.


PXMP4_HUMAN Peroxisomal membrane protein 4 (sprot)

A peroxisomal membrane protein 4 that is encoded in the genome of human.


TX264_HUMAN Testis-expressed protein 264 (sprot)

A testis-expressed protein 264 that is encoded in the genome of human.


CABIN_HUMAN Calcineurin-binding protein cabin-1 (sprot)

A calcineurin-binding protein cabin-1 that is encoded in the genome of human.


SMA5O_HUMAN SMAD5 antisense gene protein 1 (sprot)

A SMAD5 antisense gene protein 1 that is encoded in the genome of human.


KCNE2_HUMAN Potassium voltage-gated channel subfamily E member 2 (sprot)

A potassium voltage-gated channel subfamily E member 2 that is encoded in the genome of human.


STYL1_HUMAN Serine/threonine/tyrosine-interacting-like protein 1 (sprot)

A serine/threonine/tyrosine-interacting-like protein 1 that is encoded in the genome of human.


TAF6L_HUMAN TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L (sprot)

A TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L that is encoded in the genome of human.


CEPT1_HUMAN Choline/ethanolaminephosphotransferase 1 (sprot)

A choline/ethanolaminephosphotransferase 1 that is encoded in the genome of human.


1-alkenyl-2-acylglycerol choline phosphotransferase activity

Catalysis of the reaction: 1-alkenyl-2-acylglycerol + CDP-choline = plasmenylcholine + CMP.


DNM3A_HUMAN DNA (cytosine-5)-methyltransferase 3A (sprot)

A DNA (cytosine-5)-methyltransferase 3A that is encoded in the genome of human.


OAS3_HUMAN 2'-5'-oligoadenylate synthase 3 (sprot)

A 2'-5'-oligoadenylate synthase 3 that is encoded in the genome of human.


negative regulation of chemokine (C-X-C motif) ligand 9 production

Any process that stops, prevents, or reduces the frequency, rate, or extent of production of chemokine (C-X-C motif) ligand 9.


KAD5_HUMAN Adenylate kinase isoenzyme 5 (sprot)

An adenylate kinase isoenzyme 5 that is encoded in the genome of human.


dADP biosynthetic process

The chemical reactions and pathways resulting in the formation of dADP, deoxyadenosine diphosphate (2'-deoxyadenosine 5'-diphosphate).


NEMO_HUMAN NF-kappa-B essential modulator (sprot)

An NF-kappa-B essential modulator that is encoded in the genome of human.


SO1B1_HUMAN Solute carrier organic anion transporter family member 1B1 (sprot)

A solute carrier organic anion transporter family member 1B1 that is encoded in the genome of human.


TLL2_HUMAN Tolloid-like protein 2 (sprot)

A tolloid-like protein 2 that is encoded in the genome of human.


TEST_HUMAN Testisin (sprot)

A testisin that is encoded in the genome of human.


IF2B2_HUMAN Insulin-like growth factor 2 mRNA-binding protein 2 (sprot)

An insulin-like growth factor 2 mRNA-binding protein 2 that is encoded in the genome of human.


translation regulator activity, nucleic acid binding

Any selective and non-covalent interaction with a nucleic acid involved in the initiation, activation, perpetuation, repression or termination of polypeptide synthesis at the ribosome.


cold-induced thermogenesis

The process by which heat is generated by increasing metabolism in response to cold ambient temperatures in order to maintain a stable core body temperature.


KC1G3_HUMAN Casein kinase I isoform gamma-3 (sprot)

A casein kinase I isoform gamma-3 that is encoded in the genome of human.


ZNT1_HUMAN Proton-coupled zinc antiporter SLC30A1 (sprot)

A proton-coupled zinc antiporter SLC30A1 that is encoded in the genome of human.


negative regulation of zinc ion transmembrane import

Any process that stops, prevents, or reduces the frequency, rate or extent of zinc ion import.


detoxification of cadmium ion

Any process that reduces or removes the toxicity of cadmium ion. These may include transport of cadmium away from sensitive areas and to compartments or complexes whose purpose is sequestration of cadmium ion.


glutamatergic postsynaptic density

The post-synaptic specialization of a glutamatergic excitatory synapse.


S4A7_HUMAN Sodium bicarbonate cotransporter 3 (sprot)

A sodium bicarbonate cotransporter 3 that is encoded in the genome of human.


NDUB9_HUMAN NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 (sprot)

An NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 that is encoded in the genome of human.


COX11_HUMAN Cytochrome c oxidase assembly protein COX11, mitochondrial (sprot)

A cytochrome c oxidase assembly protein COX11, mitochondrial that is encoded in the genome of human.


CLCA3_HUMAN Calcium-activated chloride channel regulator family member 3 (sprot)

A calcium-activated chloride channel regulator family member 3 that is encoded in the genome of human.


SQOR_HUMAN Sulfide:quinone oxidoreductase, mitochondrial (sprot)

A sulfide:quinone oxidoreductase, mitochondrial that is encoded in the genome of human.


Catalysis of the reaction: H2S (hydrogen sulfide) + a quinone = S0 (sulfane sulfur) + a hydroquinone.


glutathione-dependent sulfide quinone oxidoreductase activity

Catalysis of the reaction: a quinone + glutathione + H(+) + hydrogen sulfide <=> a quinol + S-sulfanylglutathione.


LAMC3_HUMAN Laminin subunit gamma-3 (sprot)

A laminin subunit gamma-3 that is encoded in the genome of human.


ROBO1_HUMAN Roundabout homolog 1 (sprot)

A roundabout homolog 1 that is encoded in the genome of human.


CAD10_HUMAN Cadherin-10 (sprot)

A cadherin-10 that is encoded in the genome of human.


USH1C_HUMAN Harmonin (sprot)

A harmonin that is encoded in the genome of human.


SESN1_HUMAN Sestrin-1 (sprot)

A sestrin-1 that is encoded in the genome of human.


CAN6_HUMAN Calpain-6 (sprot)

A calpain-6 that is encoded in the genome of human.


STON1_HUMAN Stonin-1 (sprot)

A stonin-1 that is encoded in the genome of human.


ZFP37_HUMAN Zinc finger protein 37 homolog (sprot)

A zinc finger protein 37 that is encoded in the genome of human.


AP1M2_HUMAN AP-1 complex subunit mu-2 (sprot)

An AP-1 complex subunit mu-2 that is encoded in the genome of human.


TNR11_HUMAN Tumor necrosis factor receptor superfamily member 11A (sprot)

A tumor necrosis factor receptor superfamily member 11A that is encoded in the genome of human.


NCOA3_HUMAN Nuclear receptor coactivator 3 (sprot)

A nuclear receptor coactivator 3 that is encoded in the genome of human.


NUMBL_HUMAN Numb-like protein (sprot)

A Numb-like protein that is encoded in the genome of human.


S4A4_HUMAN Electrogenic sodium bicarbonate cotransporter 1 (sprot)

An electrogenic sodium bicarbonate cotransporter 1 that is encoded in the genome of human.


M3K4_HUMAN Mitogen-activated protein kinase kinase kinase 4 (sprot)

A mitogen-activated protein kinase kinase kinase 4 that is encoded in the genome of human.


Z780B_HUMAN Zinc finger protein 780B (sprot)

A zinc finger protein 780B that is encoded in the genome of human.


FCGBP_HUMAN IgGFc-binding protein (sprot)

An IgGFc-binding protein that is encoded in the genome of human.


CCD61_HUMAN Centrosomal protein CCDC61 (sprot)

A centrosomal protein CCDC61 that is encoded in the genome of human.


RPKL1_HUMAN Ribosomal protein S6 kinase-like 1 (sprot)

A ribosomal protein S6 kinase-like 1 that is encoded in the genome of human.


DGKB_HUMAN Diacylglycerol kinase beta (sprot)

A diacylglycerol kinase beta that is encoded in the genome of human.


SCIN_HUMAN Scinderin (sprot)

A scinderin that is encoded in the genome of human.


RN215_HUMAN RING finger protein 215 (sprot)

A RING finger protein 215 that is encoded in the genome of human.


PCLO_HUMAN Protein piccolo (sprot)

A protein piccolo that is encoded in the genome of human.


DDX49_HUMAN Probable ATP-dependent RNA helicase DDX49 (sprot)

A probable ATP-dependent RNA helicase DDX49 that is encoded in the genome of human.


regulation of rRNA stability

Any process that modulates the propensity of rRNA molecules to degradation. Includes processes that both stabilize and destabilize rRNAs.


CAN7_HUMAN Calpain-7 (sprot)

A calpain-7 that is encoded in the genome of human.


WASF2_HUMAN Actin-binding protein WASF2 (sprot)

An actin-binding protein WASF2 that is encoded in the genome of human.


DUS10_HUMAN Dual specificity protein phosphatase 10 (sprot)

A dual specificity protein phosphatase 10 that is encoded in the genome of human.


negative regulation of epithelium regeneration

Any process that stops, prevents or reduces the frequency, rate or extent of epithelium regeneration.


ICOS_HUMAN Inducible T-cell costimulator (sprot)

An inducible T-cell costimulator that is encoded in the genome of human.


SETBP_HUMAN SET-binding protein (sprot)

A SET-binding protein that is encoded in the genome of human.


SERP1_HUMAN Stress-associated endoplasmic reticulum protein 1 (sprot)

A stress-associated endoplasmic reticulum protein 1 that is encoded in the genome of human.


PIAS3_HUMAN E3 SUMO-protein ligase PIAS3 (sprot)

An E3 SUMO-protein ligase PIAS3 that is encoded in the genome of human.


SCC4_HUMAN MAU2 chromatid cohesion factor homolog (sprot)

A MAU2 chromatid cohesion factor homolog that is encoded in the genome of human.


F169A_HUMAN Soluble lamin-associated protein of 75 kDa (sprot)

A soluble lamin-associated protein of 75 kDa that is encoded in the genome of human.


ENPP4_HUMAN Bis(5'-adenosyl)-triphosphatase ENPP4 (sprot)

A bis(5'-adenosyl)-triphosphatase ENPP4 that is encoded in the genome of human.


purine ribonucleoside catabolic process

The chemical reactions and pathways resulting in the breakdown of any purine ribonucleoside, a nucleoside in which purine base is linked to a ribose (beta-D-ribofuranose) molecule.


MYO16_HUMAN Unconventional myosin-XVI (sprot)

A myosin-XVI that is encoded in the genome of human.


ZHX2_HUMAN Zinc fingers and homeoboxes protein 2 (sprot)

A zinc fingers and homeoboxes protein 2 that is encoded in the genome of human.


MORC2_HUMAN ATPase MORC2 (sprot)

An ATPase MORC2 that is encoded in the genome of human.


NS1BP_HUMAN Influenza virus NS1A-binding protein (sprot)

An influenza virus NS1A-binding protein that is encoded in the genome of human.


CMTA1_HUMAN Calmodulin-binding transcription activator 1 (sprot)

A calmodulin-binding transcription activator 1 that is encoded in the genome of human.


S23IP_HUMAN SEC23-interacting protein (sprot)

A SEC23-interacting protein that is encoded in the genome of human.


LY96_HUMAN Lymphocyte antigen 96 (sprot)

A lymphocyte antigen 96 that is encoded in the genome of human.


CF123_HUMAN Uncharacterized protein encoded by LINC01558 (sprot)

A protein that is a translation product of the LINC01558 gene in human.


KIAS1_HUMAN Putative uncharacterized protein KIF25-AS1 (sprot)


AFDDT_HUMAN Putative uncharacterized protein AFDN-DT (sprot)


COL10_HUMAN Collectin-10 (sprot)

A collectin-10 that is encoded in the genome of human.


S4R3C0_HUMAN Immunoglobulin heavy variable 3/OR16-17 (non-functional) (Fragment) (trembl)


HMN13_HUMAN Humanin-like 13 (sprot)

A protein that is a translation product of the MTRNR2L13 gene in human.


HMN11_HUMAN Humanin-like 11 (sprot)

A protein that is a translation product of the MTRNR2L11 gene in human.


A3LT2_HUMAN Alpha-1,3-galactosyltransferase 2 (sprot)

An alpha-1,3-galactosyltransferase 2 that is encoded in the genome of human.


Catalysis of the reaction: beta-D-galactosyl-(1,4)-beta-N-acetyl-D-glucosaminyl-R + UDP-galactose = alpha-D-galactosyl-(1,3)-beta-D-galactosyl-(1,4)-beta-N-acetyl-D-glucosaminyl-R + UDP.


V9GZ13_HUMAN MKKS centrosomal shuttling protein (trembl)


SACA6_HUMAN Sperm acrosome membrane-associated protein 6 (sprot)

A sperm acrosome membrane-associated protein 6 that is encoded in the genome of human.


PYDC5_HUMAN Pyrin domain-containing protein 5 (sprot)

A protein that is a translation product of the PYDC5 gene in human.


LRC66_HUMAN Leucine-rich repeat-containing protein 66 (sprot)

A leucine-rich repeat-containing protein 66 that is encoded in the genome of human.


Noc1p-Noc2p complex

A heterodimer associated with 90S and 66S preribosomes. Predominantly, but not exclusively, nucleolar; involved in ribosomal large subunit biogenesis.


single-strand break-containing DNA binding

Binding to damaged DNA containing single-strand breaks (SSBs).


FKB1C_HUMAN Peptidyl-prolyl cis-trans isomerase FKBP1C (sprot)


A0A191URJ7_HUMAN KIR2DL protein (trembl)


arginine biosynthetic process via ornithine

The chemical reactions and pathways resulting in the formation of arginine (2-amino-5-guanidinopentanoic acid) via the intermediate compound ornithine.


VWDE_HUMAN von Willebrand factor D and EGF domain-containing protein (sprot)

A von Willebrand factor D and EGF domain-containing protein that is encoded in the genome of human.


STMD1_HUMAN Stathmin domain-containing protein 1 (sprot)

A stathmin domain-containing protein 1 that is encoded in the genome of human.


DUX3_HUMAN Putative double homeobox protein 3 (sprot)

A putative double homeobox protein 3 that is encoded in the genome of human.


MAP kinase tyrosine phosphatase activity

Catalysis of the reaction: MAP kinase tyrosine phosphate + H2O = MAP kinase tyrosine + phosphate.


MA7D2_HUMAN MAP7 domain-containing protein 2 (sprot)

A MAP7 domain-containing protein 2 that is encoded in the genome of human.


cellular response to nitrogen starvation

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of nitrogen.


fumarylacetoacetase activity

Catalysis of the reaction: 4-fumarylacetoacetate + H2O = acetoacetate + fumarate + H+.


GOG8Q_HUMAN Golgin subfamily A member 8Q (sprot)

A protein that is a translation product of the GOLGA8Q gene in human.


MRCOL_HUMAN MARCO-like protein (sprot)

A protein that is a translation product of the MARCOL gene in human.


large ribosomal subunit rRNA binding

Binding to large ribosomal subunit RNA (LSU rRNA), a constituent of the large ribosomal subunit. In S. cerevisiae, this is the 25S rRNA.


PRA26_HUMAN Putative PRAME family member 26 (sprot)


glucagon receptor binding

Binding to a glucagon receptor.


isoleucine biosynthetic process

The chemical reactions and pathways resulting in the formation of isoleucine, (2R*,3R*)-2-amino-3-methylpentanoic acid.


phenylacetate catabolic process

The chemical reactions and pathways resulting in the breakdown of phenylacetate.


AN34A_HUMAN Ankyrin repeat domain-containing protein 34A (sprot)

An ankyrin repeat domain-containing protein 34A that is encoded in the genome of human.


D-serine transport

The directed movement of D-serine, the D-enantiomer of 2-amino-3-hydroxypropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


piecemeal microautophagy of the nucleus

Degradation of a cell nucleus by lysosomal microautophagy.


A0A5K1VDZ0_HUMAN KIR2DL1 protein (trembl)


granulocyte colony-stimulating factor receptor binding

Binding to a granulocyte colony-stimulating factor receptor.


Mis6-Sim4 complex

A protein complex that forms part of the inner kinetochore, which is involved in the loading of the centromeric histone h3 variant CENP-A onto centromeres and in centromere specific heterochromatin formation. The complex contains about 12 proteins, of which two are known as Mis6 and Sim4 in S. pombe and CENP-I and CENP-H in human.


nuclear pore inner ring

A subcomplex of the nuclear pore complex (NPC) that forms the inner rings of the core scaffold, a lattice-like structure that gives the NPC its shape and strength. In S. cerevisiae, the two inner rings are each composed of Nup192p, Nup188p, Nup170p and Nup157p. In vertebrates, the two inner rings are each composed of Nup205, Nup188 and Nup155. Components are arranged in 8-fold symmetrical 'spokes' around the central transport channel. A single 'spoke', can be isolated and is sometimes referred to as the Nup170 complex.


nonfunctional rRNA decay

An rRNA catabolic process that results in the targeted detection and degradation of aberrant rRNAs contained within translationally defective ribosomes, thereby acting as a quality-control system.


HNRC4_HUMAN Heterogeneous nuclear ribonucleoprotein C-like 4 (sprot)

A protein that is a translation product of the HNRNPCL4 gene in human.


isopentenyl diphosphate biosynthetic process

The chemical reactions and pathways resulting in the formation of isopentenyl diphosphate, an isomer of dimethylallyl diphosphate and the key precursor of all isoprenoids.


SPDE1_HUMAN Speedy protein E1 (sprot)

A speedy protein E1 that is encoded in the genome of human.


immunoglobulin production

The appearance of immunoglobulin due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


cytokine production

The appearance of a cytokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


CLBA1_HUMAN Uncharacterized protein CLBA1 (sprot)

An uncharacterized protein CLBA1 that is encoded in the genome of human.


peptide receptor activity

Combining with an extracellular or intracellular peptide to initiate a change in cell activity.


GOG8T_HUMAN Golgin subfamily A member 8T (sprot)

A protein that is a translation product of the GOLGA8T gene in human.


PAL4C_HUMAN Peptidyl-prolyl cis-trans isomerase A-like 4C (sprot)

A protein that is a translation product of the PPIAL4C gene in human.


KAL1L_HUMAN KAT8 regulatory NSL complex subunit 1-like protein (sprot)

A KAT8 regulatory NSL complex subunit 1-like protein that is encoded in the genome of human.


mitotic actomyosin contractile ring assembly actin filament organization

Any actin filament organization that is involved in mitotic actomyosin contractile ring assembly.


VGLL3_HUMAN Transcription cofactor vestigial-like protein 3 (sprot)

A transcription cofactor vestigial-like protein 3 that is encoded in the genome of human.


G32P1_HUMAN Putative G-protein coupled receptor GPR32P1 (sprot)


RGPD3_HUMAN RanBP2-like and GRIP domain-containing protein 3 (sprot)

A RanBP2-like and GRIP domain-containing protein 3 that is encoded in the genome of human.


hemoglobin alpha binding

Binding to a hemoglobin alpha chain.


LITAD_HUMAN LITAF domain-containing protein (sprot)


CFA97_HUMAN Cilia- and flagella-associated protein 97 (sprot)

A cilia- and flagella-associated protein 97 that is encoded in the genome of human.


maturation of LSU-rRNA

Any process involved in the maturation of a precursor Large SubUnit (LSU) ribosomal RNA (rRNA) molecule into a mature LSU-rRNA molecule.


MB3L4_HUMAN Putative methyl-CpG-binding domain protein 3-like 4 (sprot)


Golgi to plasma membrane transport vesicle

A transport vesicle that mediates transport from the Golgi to the plasma membrane, and fuses with the plasma membrane to release various cargo molecules, such as proteins or hormones, by exocytosis.


cellular response to stress

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).


embryo development

The process whose specific outcome is the progression of an embryo from its formation until the end of its embryonic life stage. The end of the embryonic stage is organism-specific. For example, for mammals, the process would begin with zygote formation and end with birth. For insects, the process would begin at zygote formation and end with larval hatching. For plant zygotic embryos, this would be from zygote formation to the end of seed dormancy. For plant vegetative embryos, this would be from the initial determination of the cell or group of cells to form an embryo until the point when the embryo becomes independent of the parent plant.


LHPL6_HUMAN LHFPL tetraspan subfamily member 6 protein (sprot)

An LHFPL tetraspan subfamily member 6 protein that is encoded in the genome of human.


A0A2R8Y5M8_HUMAN Transmembrane O-methyltransferase (trembl)


VSXL2_HUMAN V-set and immunoglobulin domain-containing protein 10-like 2 (sprot)

A V-set and immunoglobulin domain-containing protein 10-like 2 that is encoded in the genome of human.


disruption of plasma membrane integrity in another organism

The disruption of the cell membrane of another organism, leading to damage or temporary subversion of the membrane.


animal organ development

Development of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.


synaptic signaling

Cell-cell signaling to, from or within a synapse.


immunoglobulin complex, circulating

An immunoglobulin complex that is secreted into extracellular space and found in mucosal areas or other tissues or circulating in the blood or lymph. In its canonical form, a circulating immunoglobulin complex is composed of two identical heavy chains and two identical light chains, held together by disulfide bonds. Some forms of are polymers of the basic structure and contain additional components such as J-chain and the secretory component.


IGFL4_HUMAN Insulin growth factor-like family member 4 (sprot)

An insulin growth factor-like family member 4 that is encoded in the genome of human.


adenosine 5'-(hexahydrogen pentaphosphate) catabolic process

The chemical reactions and pathways resulting in the breakdown of adenosine 5'-(hexahydrogen pentaphosphate).


nuclear polyadenylation-dependent tRNA catabolic process

The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of an aberrant or incorrectly modified transfer RNA (tRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target tRNA.


GPR33_HUMAN Probable G-protein coupled receptor 33 (sprot)

A probable G-protein coupled receptor 33 that is encoded in the genome of human.


RMXL3_HUMAN RNA-binding motif protein, X-linked-like-3 (sprot)

An RNA-binding motif protein, X-linked-like-3 that is encoded in the genome of human.


regulation of establishment of bipolar cell polarity

Any process that modulates the rate, frequency or extent of the establishment of bipolar cell polarity. Bipolar organization is the organization that is a mirror image along an axis from a plane.


PLS5_HUMAN Phospholipid scramblase family member 5 (sprot)

A phospholipid scramblase family member 5 that is encoded in the genome of human.


intracellular anatomical structure

A component of a cell contained within (but not including) the plasma membrane. In eukaryotes it includes the nucleus and cytoplasm.


A0A0G2JNG1_HUMAN Killer cell immunoglobulin-like receptor 2DS5 (trembl)


The directed movement of nucleotide-sugars into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Nucleotide-sugars are any nucleotide in which the distal phosphoric residue of a nucleoside 5'-diphosphate is in glycosidic linkage with a monosaccharide or monosaccharide derivative.


GOG8C_HUMAN Golgin subfamily A member 8C (sprot)


AB12B_HUMAN Protein ABHD12B (sprot)

A protein ABHD12B that is encoded in the genome of human.


MRFL_HUMAN Myelin regulatory factor-like protein (sprot)

A myelin regulatory factor-like protein that is encoded in the genome of human.


mitotic G1 phase

The cell cycle 'gap' phase which is the interval between the completion of DNA segregation by mitosis and the beginning of DNA synthesis.


AMPQ_HUMAN Aminopeptidase Q (sprot)

A laeverin that is encoded in the genome of human.


equatorial microtubule organizing center

A microtubule organizing center formed by a band of gamma-tubulin that is recruited to a circumferential band of F-actin at the midpoint of a cell and which nucleates microtubules from the cell division site at the end of mitosis.


anatomical structure development

The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.