NPAS4_HUMAN Neuronal PAS domain-containing protein 4 (sprot)

A neuronal PAS domain-containing protein 4 that is encoded in the genome of human.


CLC10_HUMAN C-type lectin domain family 10 member A (sprot)

A C-type lectin domain family 10 member A that is encoded in the genome of human.


CLVS1_HUMAN Clavesin-1 (sprot)

A clavesin-1 that is encoded in the genome of human.


SIAH1_HUMAN E3 ubiquitin-protein ligase SIAH1 (sprot)

An E3 ubiquitin-protein ligase SIAH1 that is encoded in the genome of human.


TPPC5_HUMAN Trafficking protein particle complex subunit 5 (sprot)

A trafficking protein particle complex subunit 5 that is encoded in the genome of human.


TMTC1_HUMAN Protein O-mannosyl-transferase TMTC1 (sprot)

A protein O-mannosyl-transferase TMTC1 that is encoded in the genome of human.


CRERF_HUMAN CREB3 regulatory factor (sprot)

A CREB3 regulatory factor that is encoded in the genome of human.


ARMC8_HUMAN Armadillo repeat-containing protein 8 (sprot)

An armadillo repeat-containing protein 8 that is encoded in the genome of human.


EPHX4_HUMAN Epoxide hydrolase 4 (sprot)

An epoxide hydrolase 4 that is encoded in the genome of human.


SPA2L_HUMAN Spermatogenesis-associated protein 2-like protein (sprot)

A spermatogenesis-associated protein 2-like protein that is encoded in the genome of human.


RELL1_HUMAN RELT-like protein 1 (sprot)

A RELT-like protein 1 that is encoded in the genome of human.


T126B_HUMAN Complex I assembly factor TMEM126B, mitochondrial (sprot)

A complex I assembly factor TMEM126B, mitochondrial that is encoded in the genome of human.


ABC3F_HUMAN DNA dC->dU-editing enzyme APOBEC-3F (sprot)

A DNA dC->dU-editing enzyme APOBEC-3F that is encoded in the genome of human.


AEBP1_HUMAN Adipocyte enhancer-binding protein 1 (sprot)

An adipocyte enhancer-binding protein 1 that is encoded in the genome of human.


EGFL6_HUMAN Epidermal growth factor-like protein 6 (sprot)

An epidermal growth factor-like protein 6 that is encoded in the genome of human.


GRM2A_HUMAN GRAM domain-containing protein 2A (sprot)

A GRAM domain-containing protein 2A that is encoded in the genome of human.


LRC49_HUMAN Leucine-rich repeat-containing protein 49 (sprot)

A leucine-rich repeat-containing protein 49 that is encoded in the genome of human.


AT2L2_HUMAN 5-phosphohydroxy-L-lysine phospho-lyase (sprot)

An alanine--glyoxylate aminotransferase 2-like 2 that is encoded in the genome of human.


SYT12_HUMAN Synaptotagmin-12 (sprot)

A synaptotagmin-12 that is encoded in the genome of human.


spontaneous exocytosis of neurotransmitter

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The release of a neurotransmitter into the synaptic cleft, where the release step is independent of the presence of calcium ions (Ca2+). The neurotransmitter is contained within a membrane-bounded vesicle, and is released by fusion of the vesicle with the presynaptic plasma membrane of a nerve cell.


LUR1L_HUMAN Leucine rich adaptor protein 1-like (sprot)

A leucine rich adaptor protein 1-like that is encoded in the genome of human.


TB10C_HUMAN Carabin (sprot)

A carabin that is encoded in the genome of human.


PLD3_HUMAN 5'-3' exonuclease PLD3 (sprot)

A 5'-3' exonuclease PLD3 that is encoded in the genome of human.


single-stranded DNA 5'-3' DNA exonuclease activity

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Catalysis of the sequential cleavage of nucleotides (such as mononucleotides or dinucleotides) from a free 5' terminus of a single-stranded DNA molecule.


CCNJL_HUMAN Cyclin-J-like protein (sprot)

A cyclin-J-like protein that is encoded in the genome of human.


HDBP1_HUMAN Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1 (sprot)

A glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1 that is encoded in the genome of human.


chylomicron binding

Binding to a chylomicron, a large lipoprotein particle (diameter 75-1200 nm) composed of a central core of triglycerides and cholesterol surrounded by a protein-phospholipid coating. The proteins include one molecule of apolipoprotein B-48 and may include a variety of apolipoproteins, including APOAs, APOCs and APOE.


positive regulation of chylomicron remnant clearance

Any process that increases the rate, frequency or extent of chylomicron remnant clearance. Chylomicron clearance is the process in which a chylomicron remnant is removed from the blood via receptor-mediated endocytosis into liver cells and its constituent parts degraded.


LACC1_HUMAN Purine nucleoside phosphorylase LACC1 (sprot)

A purine nucleoside phosphorylase LACC1 that is encoded in the genome of human.


Catalysis of the reaction: 5'-methylthioadenosine + phosphate = adenine + 5-methylthio-D-ribose 1-phosphate.


regulation of purine nucleotide metabolic process

Any process that modulates the frequency, rate or extent of purine nucleotide metabolic process.


TM139_HUMAN Transmembrane protein 139 (sprot)

A transmembrane protein 139 that is encoded in the genome of human.


K0825_HUMAN Uncharacterized protein KIAA0825 (sprot)

An uncharacterized protein KIAA0825 that is encoded in the genome of human.


HID1_HUMAN Protein HID1 (sprot)

A protein HID1 that is encoded in the genome of human.


ANKY2_HUMAN Ankyrin repeat and MYND domain-containing protein 2 (sprot)

An ankyrin repeat and MYND domain-containing protein 2 that is encoded in the genome of human.


PSTK_HUMAN L-seryl-tRNA(Sec) kinase (sprot)

An L-seryl-tRNA(Sec) kinase that is encoded in the genome of human.


L-seryl-tRNA(Sec) kinase activity

Catalysis of the reaction: ATP + L-seryl-tRNA(Sec) = ADP + O-phospho-L-seryl-tRNA(Sec).


UN5CL_HUMAN UNC5C-like protein (sprot)

An UNC5C-like protein that is encoded in the genome of human.


netrin receptor activity

Combining with a netrin signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


ERI1_HUMAN 3'-5' exoribonuclease 1 (sprot)

A 3'-5' exoribonuclease 1 that is encoded in the genome of human.


rRNA 3'-end processing

Any process involved in forming the mature 3' end of an rRNA molecule.


DEN1C_HUMAN DENN domain-containing protein 1C (sprot)

A DENN domain-containing protein 1C that is encoded in the genome of human.


PRR15_HUMAN Proline-rich protein 15 (sprot)

A proline-rich protein 15 that is encoded in the genome of human.


GRP3_HUMAN Ras guanyl-releasing protein 3 (sprot)

A Ras guanyl-releasing protein 3 that is encoded in the genome of human.


VRK3_HUMAN Inactive serine/threonine-protein kinase VRK3 (sprot)

An inactive serine/threonine-protein kinase VRK3 that is encoded in the genome of human.


PASD1_HUMAN Circadian clock protein PASD1 (sprot)

A circadian clock protein PASD1 that is encoded in the genome of human.


Cry-Per complex

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Nuclear transcriptional repressor complex that is capable of negatively regulating CLOCK-BMAL-dependent transactivation of genes in a delayed negative feedback manner which generates circadian rhythms.


CNGA4_HUMAN Cyclic nucleotide-gated cation channel alpha-4 (sprot)

A cyclic nucleotide-gated cation channel alpha-4 that is encoded in the genome of human.


PCP2_HUMAN Purkinje cell protein 2 homolog (sprot)

A Purkinje cell protein 2 that is encoded in the genome of human.


SL9A9_HUMAN Sodium/hydrogen exchanger 9 (sprot)

A sodium/hydrogen exchanger 9 that is encoded in the genome of human.


LIX1L_HUMAN LIX1-like protein (sprot)

A LIX1-like protein that is encoded in the genome of human.


ZN584_HUMAN Zinc finger protein 584 (sprot)

A zinc finger protein 584 that is encoded in the genome of human.


NUDC3_HUMAN NudC domain-containing protein 3 (sprot)

A NudC domain-containing protein 3 that is encoded in the genome of human.


PKHH2_HUMAN Pleckstrin homology domain-containing family H member 2 (sprot)

A pleckstrin homology domain-containing family H member 2 that is encoded in the genome of human.


AHNK2_HUMAN Protein AHNAK2 (sprot)

A protein AHNAK2 that is encoded in the genome of human.


DYH10_HUMAN Dynein axonemal heavy chain 10 (sprot)

A dynein axonemal heavy chain 10 that is encoded in the genome of human.


TIAM2_HUMAN Rho guanine nucleotide exchange factor TIAM2 (sprot)

A Rho guanine nucleotide exchange factor TIAM2 that is encoded in the genome of human.


FMNL3_HUMAN Formin-like protein 3 (sprot)

A formin-like protein 3 that is encoded in the genome of human.


SAM9L_HUMAN Sterile alpha motif domain-containing protein 9-like (sprot)

A sterile alpha motif domain-containing protein 9-like that is encoded in the genome of human.


HUNIN_HUMAN Humanin (sprot)

A humanin that is encoded in the genome of human.


FOXP4_HUMAN Forkhead box protein P4 (sprot)

A forkhead box protein P4 that is encoded in the genome of human.


MMAA_HUMAN Methylmalonic aciduria type A protein, mitochondrial (sprot)

A methylmalonic aciduria type A, mitochondrial that is encoded in the genome of human.


M4K3_HUMAN Mitogen-activated protein kinase kinase kinase kinase 3 (sprot)

A mitogen-activated protein kinase kinase kinase kinase 3 that is encoded in the genome of human.


NOSTN_HUMAN Nostrin (sprot)

A nostrin that is encoded in the genome of human.


S41A1_HUMAN Solute carrier family 41 member 1 (sprot)

A solute carrier family 41 member 1 that is encoded in the genome of human.


inorganic cation transmembrane transporter activity

Enables the transfer of inorganic cations from one side of a membrane to the other. Inorganic cations are atoms or small molecules with a positive charge that do not contain carbon in covalent linkage.


Catalysis of the reaction: Na+(in) + Mg2+(out) = Na+(out) + Mg2+(in).


APRG1_HUMAN APRG1 tumor suppressor candidate (sprot)

An APRG1 tumor suppressor candidate that is encoded in the genome of human.


GLCM1_HUMAN Putative glycosylation-dependent cell adhesion molecule 1 (sprot)


NAV3_HUMAN Neuron navigator 3 (sprot)

A neuron navigator 3 that is encoded in the genome of human.


NAV2_HUMAN Neuron navigator 2 (sprot)

A neuron navigator 2 that is encoded in the genome of human.


regulation of systemic arterial blood pressure by baroreceptor feedback

The neural regulation of blood pressure in which baroreceptors sense the amount of stretch occurring in vessels and respond to the input via central nervous system control.


glossopharyngeal nerve development

Various sensory and motor branches of the glossopharyngeal nerve supply nerve connections to the pharynx and back of the tongue. The branchial motor component contains motor fibers that innervate muscles that elevate the pharynx and larynx, and the tympanic branch supplies parasympathetic fibers to the otic ganglion.


vagus nerve development

The process whose specific outcome is the progression of the vagus nerve over time, from its formation to the mature structure. This nerve is primarily sensory but also has visceromotor components. It originates in the brain stem and controls many autonomic functions of the heart, lungs, stomach, pharynx, larynx, trachea, esophagus and other gastrointestinal tract components. It controls some motor functions such as speech. The sensory branches mediate sensation from the pharynx, larynx, thorax and abdomen; it also innervates taste buds in the epiglottis.


P3H2_HUMAN Prolyl 3-hydroxylase 2 (sprot)

A prolyl 3-hydroxylase 2 that is encoded in the genome of human.


peptidyl-proline hydroxylation

The hydroxylation of peptidyl-proline to form peptidyl-hydroxyproline.


P3H3_HUMAN Prolyl 3-hydroxylase 3 (sprot)

A prolyl 3-hydroxylase 3 that is encoded in the genome of human.


CBPO_HUMAN Carboxypeptidase O (sprot)

A carboxypeptidase O that is encoded in the genome of human.


CCD50_HUMAN Coiled-coil domain-containing protein 50 (sprot)

A coiled-coil domain-containing protein 50 that is encoded in the genome of human.


S22A9_HUMAN Organic anion transporter 7 (sprot)

An organic anion transporter 7 that is encoded in the genome of human.


hormone transport

The directed movement of hormones into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


short-chain fatty acid transmembrane transport

The directed movement of short-chain fatty acids into a cell or organelle. A short-chain fatty acid is a fatty acid with an aliphatic tail of less than 6 carbons.


MSTN1_HUMAN Musculoskeletal embryonic nuclear protein 1 (sprot)

A musculoskeletal embryonic nuclear protein 1 that is encoded in the genome of human.


SBSPO_HUMAN Somatomedin-B and thrombospondin type-1 domain-containing protein (sprot)

A somatomedin-B and thrombospondin type-1 domain-containing protein that is encoded in the genome of human.


FUND1_HUMAN FUN14 domain-containing protein 1 (sprot)

A FUN14 domain-containing protein 1 that is encoded in the genome of human.


ZN547_HUMAN Zinc finger protein 547 (sprot)

A zinc finger protein 547 that is encoded in the genome of human.


ZDH21_HUMAN Palmitoyltransferase ZDHHC21 (sprot)

A palmitoyltransferase ZDHHC21 that is encoded in the genome of human.


regulation of leukocyte adhesion to arterial endothelial cell

Any process that modulates the frequency, rate or extent of leukocyte adhesion to arterial endothelial cell.


FABD_HUMAN Malonyl-CoA-acyl carrier protein transacylase, mitochondrial (sprot)

A malonyl-CoA-acyl carrier protein transacylase, mitochondrial that is encoded in the genome of human.


GLCTK_HUMAN Glycerate kinase (sprot)

A glycerate kinase that is encoded in the genome of human.


glycerate kinase activity

Catalysis of the reaction: D-glycerate + ATP = 3-phospho-D-glycerate + ADP + 2 H+.


MISP_HUMAN Mitotic interactor and substrate of PLK1 (sprot)

A mitotic interactor and substrate of PLK1 that is encoded in the genome of human.


KSR1_HUMAN Kinase suppressor of Ras 1 (sprot)

A kinase suppressor of Ras 1 that is encoded in the genome of human.


IGDC3_HUMAN Immunoglobulin superfamily DCC subclass member 3 (sprot)

An immunoglobulin superfamily DCC subclass member 3 that is encoded in the genome of human.


HERC6_HUMAN Probable E3 ubiquitin-protein ligase HERC6 (sprot)

A probable E3 ubiquitin-protein ligase HERC6 that is encoded in the genome of human.


CBCO1_HUMAN Ciliary-associated calcium-binding coiled-coil protein 1 (sprot)

A ciliary-associated calcium-binding coiled-coil protein 1 that is encoded in the genome of human.


LOXH1_HUMAN Lipoxygenase homology domain-containing protein 1 (sprot)

A lipoxygenase homology domain-containing protein 1 that is encoded in the genome of human.


GID4_HUMAN Glucose-induced degradation protein 4 homolog (sprot)

A glucose-induced degradation protein 4 homolog that is encoded in the genome of human.


NKAI4_HUMAN Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 4 (sprot)

A sodium/potassium-transporting ATPase subunit beta-1-interacting protein 4 that is encoded in the genome of human.


ARL17_HUMAN ADP-ribosylation factor-like protein 17 (sprot)

An ADP-ribosylation factor-like protein 17 that is encoded in the genome of human.


CDKL3_HUMAN Cyclin-dependent kinase-like 3 (sprot)

A cyclin-dependent kinase-like 3 that is encoded in the genome of human.


ARI3B_HUMAN AT-rich interactive domain-containing protein 3B (sprot)

An AT-rich interactive domain-containing protein 3B that is encoded in the genome of human.


SPNS2_HUMAN Sphingosine-1-phosphate transporter SPNS2 (sprot)

A sphingosine-1-phosphate transporter SPNS2 that is encoded in the genome of human.


regulation of eye pigmentation

Any process that modulates the frequency, rate or extent of establishment of a pattern of pigment in the eye of an organism.


CA210_HUMAN Type III endosome membrane protein TEMP (sprot)

A type III endosome membrane protein TEMP that is encoded in the genome of human.


VSTM4_HUMAN V-set and transmembrane domain-containing protein 4 (sprot)

A V-set and transmembrane domain-containing protein 4 that is encoded in the genome of human.


SIAH3_HUMAN Seven in absentia homolog 3 (sprot)

A seven in absentia homolog 3 that is encoded in the genome of human.


APLF_HUMAN Aprataxin and PNK-like factor (sprot)

An aprataxin and PNK-like factor that is encoded in the genome of human.


CEP97_HUMAN Centrosomal protein of 97 kDa (sprot)

A centrosomal protein of 97 kDa that is encoded in the genome of human.


ZN695_HUMAN Zinc finger protein 695 (sprot)

A zinc finger protein 695 that is encoded in the genome of human.


CC103_HUMAN Coiled-coil domain-containing protein 103 (sprot)

A coiled-coil domain-containing protein 103 that is encoded in the genome of human.


MAPK5_HUMAN MAP kinase-activated protein kinase 5 (sprot)

A MAP kinase-activated protein kinase 5 that is encoded in the genome of human.


NNRD_HUMAN ATP-dependent (S)-NAD(P)H-hydrate dehydratase (sprot)

An ATP-dependent (S)-NAD(P)H-hydrate dehydratase that is encoded in the genome of human.


ATP-dependent NAD(P)H-hydrate dehydratase activity

Catalysis of the reaction: (6S)-6beta-hydroxy-1,4,5,6-tetrahydronicotinamide adenine dinucleotide + ATP = ADP + 3 H+ + NADH + phosphate.


SLIK4_HUMAN SLIT and NTRK-like protein 4 (sprot)

A SLIT and NTRK-like protein 4 that is encoded in the genome of human.


T151B_HUMAN Transmembrane protein 151B (sprot)

A transmembrane protein 151B that is encoded in the genome of human.


SPA12_HUMAN Serpin A12 (sprot)

A serpin A12 that is encoded in the genome of human.


GLBL2_HUMAN Beta-galactosidase-1-like protein 2 (sprot)

A beta-galactosidase-1-like protein 2 that is encoded in the genome of human.


ARHGJ_HUMAN Rho guanine nucleotide exchange factor 19 (sprot)

A Rho guanine nucleotide exchange factor 19 that is encoded in the genome of human.


WDR75_HUMAN WD repeat-containing protein 75 (sprot)

A WD repeat-containing protein 75 that is encoded in the genome of human.


MFN1_HUMAN Mitofusin-1 (sprot)

A mitofusin-1 that is encoded in the genome of human.


outer mitochondrial membrane protein complex

Any protein complex that is part of the outer mitochondrial membrane.


CTL2_HUMAN Choline transporter-like protein 2 (sprot)

A choline transporter-like protein 2 that is encoded in the genome of human.


ethanolamine transmembrane transporter activity

Enables the transfer of ethanolamine from one side of a membrane to the other. Ethanolamine (2-aminoethanol, monoethanolamine) is an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids, such as phosphatidylethanolamine.


ethanolamine transport

The directed movement of ethanolamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Ethanolamine (2-aminoethanol, monoethanolamine) is an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids, such as phosphatidylethanolamine.


CCD60_HUMAN Coiled-coil domain-containing protein 60 (sprot)

A coiled-coil domain-containing protein 60 that is encoded in the genome of human.


IPRI_HUMAN Inositol 1,4,5-trisphosphate receptor-interacting protein (sprot)

An inositol 1,4,5-trisphosphate receptor-interacting protein that is encoded in the genome of human.


S31A7_HUMAN Spermatogenesis-associated protein 31A7 (sprot)

A spermatogenesis-associated protein 31A7 that is encoded in the genome of human.


TEX14_HUMAN Inactive serine/threonine-protein kinase TEX14 (sprot)

A testis-expressed protein 14 that is encoded in the genome of human.


intercellular bridge organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the intracellular bridge. An intracellular bridge is a direct link between the cytoplasms of sister cells that allows cells to communicate with one another.


WDFY1_HUMAN WD repeat and FYVE domain-containing protein 1 (sprot)

A WD repeat and FYVE domain-containing protein 1 that is encoded in the genome of human.


TEX2_HUMAN Testis-expressed protein 2 (sprot)

A testis-expressed protein 2 that is encoded in the genome of human.


MA7D3_HUMAN MAP7 domain-containing protein 3 (sprot)

A MAP7 domain-containing protein 3 that is encoded in the genome of human.


CC117_HUMAN Coiled-coil domain-containing protein 117 (sprot)

A coiled-coil domain-containing protein 117 that is encoded in the genome of human.


NXP20_HUMAN Protein NOXP20 (sprot)

A protein NOXP20 that is encoded in the genome of human.


DCNL3_HUMAN DCN1-like protein 3 (sprot)

A DCN1-like protein 3 that is encoded in the genome of human.


PKHM2_HUMAN Pleckstrin homology domain-containing family M member 2 (sprot)

A pleckstrin homology domain-containing family M member 2 that is encoded in the genome of human.


FXRD2_HUMAN FAD-dependent oxidoreductase domain-containing protein 2 (sprot)

An FAD-dependent oxidoreductase domain-containing protein 2 that is encoded in the genome of human.


DEN6A_HUMAN Protein DENND6A (sprot)

A protein FAM116A that is encoded in the genome of human.


CCD83_HUMAN Coiled-coil domain-containing protein 83 (sprot)

A coiled-coil domain-containing protein 83 that is encoded in the genome of human.


DNAI3_HUMAN Dynein axonemal intermediate chain 3 (sprot)

A dynein axonemal intermediate chain 3 that is encoded in the genome of human.


MGAP_HUMAN MAX gene-associated protein (sprot)

A MAX gene-associated protein that is encoded in the genome of human.


GCC2_HUMAN GRIP and coiled-coil domain-containing protein 2 (sprot)

A GRIP and coiled-coil domain-containing protein 2 that is encoded in the genome of human.


regulation of protein exit from endoplasmic reticulum

Any process that modulates the frequency, rate or extent of the directed movement of proteins from the endoplasmic reticulum.


recycling endosome to Golgi transport

The directed movement of substances from recycling endosomes to the Golgi.


AGRA3_HUMAN Adhesion G protein-coupled receptor A3 (sprot)

An adhesion G protein-coupled receptor A3 that is encoded in the genome of human.


SFPA2_HUMAN Pulmonary surfactant-associated protein A2 (sprot)

A pulmonary surfactant-associated protein A2 that is encoded in the genome of human.


SFTA1_HUMAN Pulmonary surfactant-associated protein A1 (sprot)

A pulmonary surfactant-associated protein A1 that is encoded in the genome of human.


HSC20_HUMAN Iron-sulfur cluster co-chaperone protein HscB (sprot)

An iron-sulfur cluster co-chaperone protein HscB that is encoded in the genome of human.


STH_HUMAN Saitohin (sprot)

A saitohin that is encoded in the genome of human.


RP1L1_HUMAN Retinitis pigmentosa 1-like 1 protein (sprot)

A retinitis pigmentosa 1-like 1 protein that is encoded in the genome of human.


CC28A_HUMAN Coiled-coil domain-containing protein 28A (sprot)

A coiled-coil domain-containing protein 28A that is encoded in the genome of human.


BRSK2_HUMAN Serine/threonine-protein kinase BRSK2 (sprot)

A serine/threonine-protein kinase BRSK2 that is encoded in the genome of human.


ATPase regulator activity

Binds to and modulates the activity of an ATP hydrolysis activity.


regulation of retrograde protein transport, ER to cytosol

Any process that modulates the frequency, rate or extent of retrograde protein transport, ER to cytosol.


Z3H7A_HUMAN Zinc finger CCCH domain-containing protein 7A (sprot)

A zinc finger CCCH domain-containing protein 7A that is encoded in the genome of human.


TRI59_HUMAN Tripartite motif-containing protein 59 (sprot)

A tripartite motif-containing protein 59 that is encoded in the genome of human.


PHF6_HUMAN PHD finger protein 6 (sprot)

A PHD finger protein 6 that is encoded in the genome of human.


ARCH_HUMAN Protein archease (sprot)

A protein archease that is encoded in the genome of human.


SCN4B_HUMAN Sodium channel subunit beta-4 (sprot)

A sodium channel subunit beta-4 that is encoded in the genome of human.


CUL9_HUMAN Cullin-9 (sprot)

A cullin-9 that is encoded in the genome of human.


LRC8A_HUMAN Volume-regulated anion channel subunit LRRC8A (sprot)

A volume-regulated anion channel subunit LRRC8A that is encoded in the genome of human.


pre-B cell differentiation

The process in which a precursor cell type acquires the specialized features of a pre-B cell. Pre-B cells follow the pro-B cell stage of immature B cell differentiation and undergo rearrangement of heavy chain V, D, and J gene segments.


LMTK2_HUMAN Serine/threonine-protein kinase LMTK2 (sprot)

A serine/threonine-protein kinase LMTK2 that is encoded in the genome of human.


ZNT8_HUMAN Proton-coupled zinc antiporter SLC30A8 (sprot)

A proton-coupled zinc antiporter SLC30A8 that is encoded in the genome of human.


SULF2_HUMAN Extracellular sulfatase Sulf-2 (sprot)

An extracellular sulfatase Sulf-2 that is encoded in the genome of human.


esophagus smooth muscle contraction

A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the esophagus. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The esophagus is the muscular membranous segment between the pharynx and the stomach in the upper gastrointestinal tract.


SULF1_HUMAN Extracellular sulfatase Sulf-1 (sprot)

An extracellular sulfatase Sulf-1 that is encoded in the genome of human.


TPH2_HUMAN Tryptophan 5-hydroxylase 2 (sprot)

A tryptophan 5-hydroxylase 2 that is encoded in the genome of human.


tryptophan 5-monooxygenase activity

Catalysis of the reaction: L-tryptophan + tetrahydrobiopterin + O2 = 5-hydroxy-L-tryptophan + 4-alpha-hydroxytetrahydrobiopterin + H2O.


LAX1_HUMAN Lymphocyte transmembrane adapter 1 (sprot)

A lymphocyte transmembrane adapter 1 that is encoded in the genome of human.


CNTN4_HUMAN Contactin-4 (sprot)

A contactin-4 that is encoded in the genome of human.


UBR1_HUMAN E3 ubiquitin-protein ligase UBR1 (sprot)

An E3 ubiquitin-protein ligase UBR1 that is encoded in the genome of human.


UBR2_HUMAN E3 ubiquitin-protein ligase UBR2 (sprot)

An E3 ubiquitin-protein ligase UBR2 that is encoded in the genome of human.


RHG12_HUMAN Rho GTPase-activating protein 12 (sprot)

A Rho GTPase-activating protein 12 that is encoded in the genome of human.


HOT_HUMAN Hydroxyacid-oxoacid transhydrogenase, mitochondrial (sprot)

A hydroxyacid-oxoacid transhydrogenase, mitochondrial that is encoded in the genome of human.


Catalysis of the reaction: (S)-3-hydroxybutanoate + 2-oxoglutarate = acetoacetate + (R)-2-hydroxyglutarate.


glutamate catabolic process via 2-oxoglutarate

The chemical reactions and pathways resulting in the breakdown of glutamate, via the intermediate 2-oxoglutarate.


SGPP2_HUMAN Sphingosine-1-phosphate phosphatase 2 (sprot)

A sphingosine-1-phosphate phosphatase 2 that is encoded in the genome of human.


Catalysis of the reaction: dihydrosphingosine 1-phosphate + H2O = dihydrosphingosine + phosphate.


UN45B_HUMAN Protein unc-45 homolog B (sprot)

A protein unc-45 homolog B that is encoded in the genome of human.


CHERP_HUMAN Calcium homeostasis endoplasmic reticulum protein (sprot)

A calcium homeostasis endoplasmic reticulum protein that is encoded in the genome of human.


SCUB1_HUMAN Signal peptide, CUB and EGF-like domain-containing protein 1 (sprot)

A signal peptide, CUB and EGF-like domain-containing protein 1 that is encoded in the genome of human.


ZSC29_HUMAN Zinc finger and SCAN domain-containing protein 29 (sprot)

A zinc finger and SCAN domain-containing protein 29 that is encoded in the genome of human.


CDAN1_HUMAN Codanin-1 (sprot)

A codanin-1 that is encoded in the genome of human.


ANKH1_HUMAN Ankyrin repeat and KH domain-containing protein 1 (sprot)

An ankyrin repeat and KH domain-containing protein 1 that is encoded in the genome of human.


TRI48_HUMAN E3 ubiquitin-protein ligase TRIM48 (sprot)

An E3 ubiquitin-protein ligase TRIM48 that is encoded in the genome of human.


TRI42_HUMAN Tripartite motif-containing protein 42 (sprot)

A tripartite motif-containing protein 42 that is encoded in the genome of human.


BBS7_HUMAN Bardet-Biedl syndrome 7 protein (sprot)

A Bardet-Biedl syndrome 7 protein that is encoded in the genome of human.


pigment granule aggregation in cell center

The directed movement of dispersed pigment granules towards the center of the cell.


SUGP1_HUMAN SURP and G-patch domain-containing protein 1 (sprot)

A splicing factor 4 that is encoded in the genome of human.


SUGP2_HUMAN SURP and G-patch domain-containing protein 2 (sprot)

A SURP and G-patch domain-containing protein 2 that is encoded in the genome of human.


KIBRA_HUMAN Protein KIBRA (sprot)

A protein WWC1 that is encoded in the genome of human.


UEVLD_HUMAN Ubiquitin-conjugating enzyme E2 variant 3 (sprot)

A ubiquitin-conjugating enzyme E2 variant 3 that is encoded in the genome of human.


CD302_HUMAN CD302 antigen (sprot)

A CD302 molecule that is encoded in the genome of human.


GOR_HUMAN Putative exonuclease GOR (sprot)

A putative exonuclease GOR that is encoded in the genome of human.


FOG1_HUMAN Zinc finger protein ZFPM1 (sprot)

A zinc finger protein ZFPM1 that is encoded in the genome of human.


T-helper cell lineage commitment

The process in which a CD4-positive, alpha-beta T cell becomes committed to becoming a T-helper cell, a CD4-positive, alpha-beta T cell specialized to promote various immunological processes.


tricuspid valve formation

The developmental process pertaining to the initial formation of the tricuspid valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable.


negative regulation of mast cell differentiation

Any process that decreases the rate, frequency or extent of mast cell differentiation, the process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a mast cell. A mast cell is a cell that is found in almost all tissues containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation.


CCAR1_HUMAN Cell division cycle and apoptosis regulator protein 1 (sprot)

A cell division cycle and apoptosis regulator protein 1 that is encoded in the genome of human.


HOMEZ_HUMAN Homeobox and leucine zipper protein Homez (sprot)

A homeobox and leucine zipper protein Homez that is encoded in the genome of human.


DHX40_HUMAN Probable ATP-dependent RNA helicase DHX40 (sprot)

A probable ATP-dependent RNA helicase DHX40 that is encoded in the genome of human.


MCEM1_HUMAN Mast cell-expressed membrane protein 1 (sprot)

A mast cell-expressed membrane protein 1 that is encoded in the genome of human.


SLF2_HUMAN SMC5-SMC6 complex localization factor protein 2 (sprot)

An SMC5-SMC6 complex localization factor protein 2 that is encoded in the genome of human.


Smc5-Smc6 complex

A conserved complex that contains a heterodimer of SMC proteins (Smc5p and Smc6p, or homologs thereof) and several other proteins, and is involved in DNA repair and maintaining cell cycle arrest following DNA damage. In S. cerevisiae, this is an octameric complex called Mms21-Smc5-Smc6 complex, with at least five of its subunits conserved in fission yeast and humans.


FBX16_HUMAN F-box only protein 16 (sprot)

An F-box only protein 16 that is encoded in the genome of human.


SCUB3_HUMAN Signal peptide, CUB and EGF-like domain-containing protein 3 (sprot)

A signal peptide, CUB and EGF-like domain-containing protein 3 that is encoded in the genome of human.


SKA3_HUMAN Spindle and kinetochore-associated protein 3 (sprot)

A spindle and kinetochore-associated protein RAMA1 that is encoded in the genome of human.


CTGE4_HUMAN cTAGE family member 4 (sprot)

A cTAGE family member 4 that is encoded in the genome of human.


CTGE3_HUMAN Putative cTAGE family member 3 (sprot)

A cutaneous T-cell lymphoma-associated antigen 3 that is encoded in the genome of human.


SACA3_HUMAN Sperm acrosome membrane-associated protein 3 (sprot)

A sperm acrosome membrane-associated protein 3 that is encoded in the genome of human.


DJC10_HUMAN DnaJ homolog subfamily C member 10 (sprot)

A DnaJ homolog subfamily C member 10 that is encoded in the genome of human.


TARG1_HUMAN Trafficking regulator of GLUT4 1 (sprot)

A trafficking regulator of GLUT4 1 that is encoded in the genome of human.


vesicle fusion to plasma membrane

Fusion of the membrane of a vesicle with the plasma membrane, thereby releasing its contents into the extracellular space.


OR4N5_HUMAN Olfactory receptor 4N5 (sprot)

An olfactory receptor 4N5 that is encoded in the genome of human.


NPAS3_HUMAN Neuronal PAS domain-containing protein 3 (sprot)

A neuronal PAS domain-containing protein 3 that is encoded in the genome of human.


AQ12A_HUMAN Aquaporin-12A (sprot)

An aquaporin-12A that is encoded in the genome of human.


T53I2_HUMAN Tumor protein p53-inducible nuclear protein 2 (sprot)

A tumor protein p53-inducible nuclear protein 2 that is encoded in the genome of human.


negative regulation of protein localization

Any process that stops, prevents or reduces the frequency, rate or extent of a protein localization.


NELFD_HUMAN Negative elongation factor C/D (sprot)

A negative elongation factor C/D that is encoded in the genome of human.


CAD26_HUMAN Cadherin-like protein 26 (sprot)

A cadherin-like protein 26 that is encoded in the genome of human.


MIRO2_HUMAN Mitochondrial Rho GTPase 2 (sprot)

A mitochondrial Rho GTPase 2 that is encoded in the genome of human.


MIRO1_HUMAN Mitochondrial Rho GTPase 1 (sprot)

A mitochondrial Rho GTPase 1 that is encoded in the genome of human.


SIR2_HUMAN NAD-dependent protein deacetylase sirtuin-2 (sprot)

An NAD-dependent protein deacetylase sirtuin-2 that is encoded in the genome of human.


NAD-dependent histone deacetylase activity

Catalysis of the reaction: histone N6-acetyl-L-lysine + H2O = histone L-lysine + acetate. This reaction requires the presence of NAD, and represents the removal of an acetyl group from a histone.


NAD-dependent protein deacetylase activity

Catalysis of the removal of one or more acetyl groups from a protein, requiring NAD.


tubulin deacetylase activity

Catalysis of the reaction: N-acetyl(alpha-tubulin) + H2O = alpha-tubulin + acetate.


NAD-dependent histone H4K16 deacetylase activity

Catalysis of the reaction: histone H4 N6-acetyl-L-lysine (position 16) + H2O = histone H4 L-lysine (position 16) + acetate. This reaction requires the presence of NAD, and represents the removal of an acetyl group from lysine at position 16 of the histone H4 protein.


NAD-dependent protein demyristoylase activity

Catalysis of the reaction: N6-tetradecanoyl-L-lysyl-[protein] + NAD+ + H2O = tetradecanoyl-ADP-D-ribose + L-lysyl-[protein] + nicotinamide.


NAD-dependent protein depalmitoylase activity

Catalysis of the reaction: N6-octadecanoyl-L-lysyl-[protein] + NAD+ + H2O = octadecanoyl-ADP-D-ribose + L-lysyl-[protein] + nicotinamide.


cellular response to caloric restriction

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a of caloric restriction, insufficient food energy intake.


negative regulation of oligodendrocyte progenitor proliferation

Any process that stops or decreases the rate or extent of oligodendrocyte progenitor proliferation.


ASXL1_HUMAN Polycomb group protein ASXL1 (sprot)

A Polycomb group protein ASXL1 that is encoded in the genome of human.


PR-DUB complex

A multimeric protein complex that removes monoubiquitin from histone H2A. In Drosophila and mammals, the core of the complex is composed of Calypso/BAP1 and Asx/ASXL1, respectively.


PHC2_HUMAN Polyhomeotic-like protein 2 (sprot)

A polyhomeotic-like protein 2 that is encoded in the genome of human.


GLT12_HUMAN Polypeptide N-acetylgalactosaminyltransferase 12 (sprot)

A polypeptide N-acetylgalactosaminyltransferase 12 that is encoded in the genome of human.


FA20C_HUMAN Extracellular serine/threonine protein kinase FAM20C (sprot)

An extracellular serine/threonine protein kinase Fam20C that is encoded in the genome of human.


osteoclast maturation

A developmental process, independent of morphogenetic (shape) change, that is required for an osteoclast cell to attain its fully functional state. An osteoclast is a specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue, and which typically differentiates from monocytes.


regulation of phosphorus metabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus.


MSRB3_HUMAN Methionine-R-sulfoxide reductase B3 (sprot)

A methionine-R-sulfoxide reductase B3, mitochondrial that is encoded in the genome of human.


peptide-methionine (R)-S-oxide reductase activity

Catalysis of the reaction: peptide-L-methionine + H2O + thioredoxin disulfide = peptide-L-methionine (R)-S-oxide + thioredoxin. Can act on oxidized methionine in peptide linkage with specificity for the R enantiomer. Thioredoxin disulfide is the oxidized form of thioredoxin.


Catalysis of the reaction: L-methionine + thioredoxin disulfide + H2O = L-methionine (R)-S-oxide + thioredoxin.


IQCF2_HUMAN IQ domain-containing protein F2 (sprot)

An IQ domain-containing protein F2 that is encoded in the genome of human.


BAP18_HUMAN Chromatin complexes subunit BAP18 (sprot)

A protein that is a translation product of the BAP18 gene in human.


RM41_HUMAN Large ribosomal subunit protein mL41 (sprot)

A 39S ribosomal protein L41, mitochondrial that is encoded in the genome of human.


NRM_HUMAN Nurim (sprot)

A nurim that is encoded in the genome of human.


CMA1C_HUMAN Protein CIMAP1C (sprot)

An outer dense fiber protein 3-like protein 1 that is encoded in the genome of human.


RIMKA_HUMAN N-acetylaspartylglutamate synthase A (sprot)

An N-acetylaspartylglutamate synthase A that is encoded in the genome of human.


Catalysis of the reaction: ATP + N-acetyl-L-aspartate + L-glutamate = ADP + phosphate + N-acetylaspartyl-glutamate.


glutamine family amino acid metabolic process

The chemical reactions and pathways involving amino acids of the glutamine family, comprising arginine, glutamate, glutamine and proline.


OCAT1_HUMAN POU domain class 2-associating factor 2 (sprot)

A POU domain class 2-associating factor 2 that is encoded in the genome of human.


KLHL7_HUMAN Kelch-like protein 7 (sprot)

A kelch-like protein 7 that is encoded in the genome of human.


PARP9_HUMAN Protein mono-ADP-ribosyltransferase PARP9 (sprot)

A protein mono-ADP-ribosyltransferase PARP9 that is encoded in the genome of human.


ADP-D-ribose binding

Binding to ADP-D-ribose, an ADP-aldose having ribose as the aldose fragment.


NAD+-protein-C-terminal glycine ADP-ribosyltransferase activity

Catalysis of the reaction: [protein]-C-terminal glycine + NAD+ = [protein]-C-terminal O-(ADP-D-ribosyl)-glycine + nicotinamide.


regulation of response to type II interferon

Any process that modulates the rate, frequency or extent of a response to type II interferon (interferon-gamma). Response to interferon gamma is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-gamma stimulus.


ETKMT_HUMAN Electron transfer flavoprotein beta subunit lysine methyltransferase (sprot)

An electron transfer flavoprotein beta subunit lysine methyltransferase that is encoded in the genome of human.


negative regulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase

Any process that stops, prevents or reduces the frequency, rate or extent of fatty acid beta-oxidation using acyl-CoA dehydrogenase.


F217A_HUMAN Protein FAM217A (sprot)

A protein FAM217A that is encoded in the genome of human.


DRC2_HUMAN Dynein regulatory complex subunit 2 (sprot)

A dynein regulatory complex subunit 2 that is encoded in the genome of human.


HYCC2_HUMAN Hyccin 2 (sprot)

A hyccin 2 that is encoded in the genome of human.


DDIAS_HUMAN DNA damage-induced apoptosis suppressor protein (sprot)

A DNA damage-induced apoptosis suppressor protein that is encoded in the genome of human.


DMRTD_HUMAN Doublesex- and mab-3-related transcription factor C2 (sprot)

A doublesex- and mab-3-related transcription factor C2 that is encoded in the genome of human.


RB12B_HUMAN RNA-binding protein 12B (sprot)

An RNA-binding protein 12B that is encoded in the genome of human.


S35F2_HUMAN Solute carrier family 35 member F2 (sprot)

A solute carrier family 35 member F2 that is encoded in the genome of human.


KLD8B_HUMAN Kelch domain-containing protein 8B (sprot)

A kelch domain-containing protein 8B that is encoded in the genome of human.


nuclear chromosome segregation

The process in which genetic material, in the form of nuclear chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. Nuclear chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles.


mitotic cytokinetic process

Any cytokinetic process that is involved in mitotic cell cycle.


cellularization cleavage furrow

A plasma membrane invagination at the site of separation of a multi-nucleate cell or syncytium into individual cells.


LMTD2_HUMAN Lamin tail domain-containing protein 2 (sprot)

A lamin tail domain-containing protein 2 that is encoded in the genome of human.


RPAP2_HUMAN Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2 (sprot)

A putative RNA polymerase II subunit B1 CTD phosphatase RPAP2 that is encoded in the genome of human.


RNA polymerase core enzyme binding

Binding to an RNA polymerase core enzyme, containing a specific subunit composition defined as the core enzyme.


T183A_HUMAN Transmembrane protein 183A (sprot)

A transmembrane protein 183A that is encoded in the genome of human.


PPIL6_HUMAN Probable inactive peptidyl-prolyl cis-trans isomerase-like 6 (sprot)

A probable inactive peptidyl-prolyl cis-trans isomerase-like 6 that is encoded in the genome of human.


ZC3H3_HUMAN Zinc finger CCCH domain-containing protein 3 (sprot)

A zinc finger CCCH domain-containing protein 3 that is encoded in the genome of human.


SP8_HUMAN Transcription factor Sp8 (sprot)

A transcription factor Sp8 that is encoded in the genome of human.


PLPL6_HUMAN Patatin-like phospholipase domain-containing protein 6 (sprot)

A patatin-like phospholipase domain-containing protein 6 that is encoded in the genome of human.


SMC5_HUMAN Structural maintenance of chromosomes protein 5 (sprot)

A structural maintenance of chromosomes protein 5 that is encoded in the genome of human.


DNA secondary structure binding

Binding to a DNA secondary structure element such as a four-way junction, a bubble, a loop, Y-form DNA, or a double-strand/single-strand junction.


sex chromosome

A chromosome involved in sex determination.


DDX60_HUMAN Probable ATP-dependent RNA helicase DDX60 (sprot)

A probable ATP-dependent RNA helicase DDX60 that is encoded in the genome of human.


CMIP_HUMAN C-Maf-inducing protein (sprot)

A C-Maf-inducing protein that is encoded in the genome of human.


PLPP6_HUMAN Polyisoprenoid diphosphate/phosphate phosphohydrolase PLPP6 (sprot)

A polyisoprenoid diphosphate/phosphate phosphohydrolase PLPP6 that is encoded in the genome of human.


isoprenoid diphosphate phosphatase activity

Catalysis of the dephosphorylation of isoprenoid diphosphates.


protein prenylation

The covalent attachment of a prenyl group to a protein; geranyl, farnesyl, or geranylgeranyl groups may be added.


geranyl diphosphate metabolic process

The chemical reactions and pathways involving geranyl diphosphate, the universal precursor of the monoterpenes.


farnesyl diphosphate catabolic process

The chemical reactions and pathways resulting in the breakdown of farnesyl diphosphate.


geranylgeranyl diphosphate catabolic process

The chemical reactions and pathways resulting in the breakdown of geranylgeranyl diphosphate.


IFT20_HUMAN Intraflagellar transport protein 20 homolog (sprot)

An intraflagellar transport protein 20 that is encoded in the genome of human.


dendrite terminus

A structure at the distal end of a dendrite adapted to carry out a specific function, e.g. dendriole.


kinociliary basal body

A ciliary basal body that is part of a kinocilium.


MILK2_HUMAN MICAL-like protein 2 (sprot)

A MICAL-like protein 2 that is encoded in the genome of human.


S15A3_HUMAN Solute carrier family 15 member 3 (sprot)

A solute carrier family 15 member 3 that is encoded in the genome of human.


peptidoglycan transmembrane transporter activity

Enables the transfer of peptidoglycans, a class of glycoconjugates found in bacterial cell walls, from one side of a membrane to the other.


DHX37_HUMAN Probable ATP-dependent RNA helicase DHX37 (sprot)

A probable ATP-dependent RNA helicase DHX37 that is encoded in the genome of human.


CD019_HUMAN Uncharacterized protein C4orf19 (sprot)

An uncharacterized protein C4orf19 that is encoded in the genome of human.


AMN1_HUMAN Protein AMN1 homolog (sprot)

A protein AMN1 that is encoded in the genome of human.


KBTB2_HUMAN Kelch repeat and BTB domain-containing protein 2 (sprot)

A kelch repeat and BTB domain-containing protein 2 that is encoded in the genome of human.


PAQRA_HUMAN Monocyte to macrophage differentiation factor 2 (sprot)

A monocyte to macrophage differentiation factor 2 that is encoded in the genome of human.


S35F3_HUMAN Solute carrier family 35 member F3 (sprot)

A putative thiamine transporter SLC35F3 that is encoded in the genome of human.


TIGD4_HUMAN Tigger transposable element-derived protein 4 (sprot)

A tigger transposable element-derived protein 4 that is encoded in the genome of human.


YAF2_HUMAN YY1-associated factor 2 (sprot)

A YY1-associated factor 2 that is encoded in the genome of human.


AMOL1_HUMAN Angiomotin-like protein 1 (sprot)

An angiomotin-like protein 1 that is encoded in the genome of human.


RAVR1_HUMAN Ribonucleoprotein PTB-binding 1 (sprot)

A ribonucleoprotein PTB-binding 1 that is encoded in the genome of human.


SPB1_HUMAN pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3 (sprot)

An rRNA methyltransferase 3 that is encoded in the genome of human.


RNA 2'-O-methyltransferase activity

Catalysis of the reaction: S-adenosyl-L-methionine + RNA = S-adenosyl-L-homocysteine + RNA containing 2'-O-methylribonucleotide.


DRC7_HUMAN Dynein regulatory complex subunit 7 (sprot)

A dynein regulatory complex subunit 7 that is encoded in the genome of human.


NIM1_HUMAN Serine/threonine-protein kinase NIM1 (sprot)

A serine/threonine-protein kinase NIM1 that is encoded in the genome of human.


SLX4_HUMAN Structure-specific endonuclease subunit SLX4 (sprot)

A structure-specific endonuclease subunit SLX4 that is encoded in the genome of human.


response to intra-S DNA damage checkpoint signaling

A process that occurs in response to signals generated as a result of intra-S DNA damage checkpoint signaling.


Slx1-Slx4 complex

A heterodimeric protein complex that possesses an endonuclease activity that specifically cleaves certain types of branched DNA structures; because such structures often form during the replication ribosomal DNA (rDNA) repeats, the complex plays a role in the maintenance of rDNA. The subunits are known as Slx1 and Slx 4 in budding and fission yeasts, and are conserved in eukaryotes.


TM192_HUMAN Transmembrane protein 192 (sprot)

A transmembrane protein 192 that is encoded in the genome of human.


CKP2L_HUMAN Cytoskeleton-associated protein 2-like (sprot)

A cytoskeleton-associated protein 2-like that is encoded in the genome of human.


MKX_HUMAN Homeobox protein Mohawk (sprot)

A homeobox protein Mohawk that is encoded in the genome of human.


IHO1_HUMAN Interactor of HORMAD1 protein 1 (sprot)

An interactor of HORMAD1 protein 1 that is encoded in the genome of human.


M21D2_HUMAN Nucleotidyltransferase MB21D2 (sprot)

A nucleotidyltransferase MB21D2 that is encoded in the genome of human.


SRRM1_HUMAN Serine/arginine repetitive matrix protein 1 (sprot)

A serine/arginine repetitive matrix protein 1 that is encoded in the genome of human.


PEX5R_HUMAN PEX5-related protein (sprot)

A PEX5-related protein that is encoded in the genome of human.


SMAP1_HUMAN Stromal membrane-associated protein 1 (sprot)

A stromal membrane-associated protein 1 that is encoded in the genome of human.


DI3L2_HUMAN DIS3-like exonuclease 2 (sprot)

A DIS3-like exonuclease 2 that is encoded in the genome of human.


SUV3_HUMAN ATP-dependent RNA helicase SUPV3L1, mitochondrial (sprot)

An ATP-dependent RNA helicase SUPV3L1, mitochondrial that is encoded in the genome of human.


mitochondrial RNA 3'-end processing

Any process involved in forming the mature 3' end of an RNA molecule transcribed from a mitochondrial genome; occurs in the mitochondrion.


mitochondrial ncRNA surveillance

The set of processes involved in identifying and degrading defective or aberrant non-coding RNA transcripts (ncRNAs) within the mitochondrion.


mitochondrial mRNA surveillance

The set of processes involved in identifying and degrading messenger RNA (mRNA) within the mitochondrion.


mitochondrial RNA surveillance

The set of processes involved in identifying and degrading defective or aberrant RNAs that takes place in the mitochondrion.


mitochondrial degradosome

A mitochondrial protein complex with 3' to 5' exoribonuclease activity that participates in intron-independent turnover and processing of mitochondrial transcripts. In humans, the mitochondrial degradosome is a pentameric complex, and in yeast it exists as a heterodimer.


ZN595_HUMAN Zinc finger protein 595 (sprot)

A zinc finger protein 595 that is encoded in the genome of human.


ERF3B_HUMAN Eukaryotic peptide chain release factor GTP-binding subunit ERF3B (sprot)

A eukaryotic peptide chain release factor GTP-binding subunit ERF3B that is encoded in the genome of human.


KLD8A_HUMAN Kelch domain-containing protein 8A (sprot)

A kelch domain-containing protein 8A that is encoded in the genome of human.


FANCM_HUMAN Fanconi anemia group M protein (sprot)

A Fanconi anemia group M protein that is encoded in the genome of human.


LAS2_HUMAN Lung adenoma susceptibility protein 2 (sprot)

A lung adenoma susceptibility protein 2 that is encoded in the genome of human.


CC146_HUMAN Coiled-coil domain-containing protein 146 (sprot)

A coiled-coil domain-containing protein 146 that is encoded in the genome of human.


CCD13_HUMAN Coiled-coil domain-containing protein 13 (sprot)

A coiled-coil domain-containing protein 13 that is encoded in the genome of human.


ELOA2_HUMAN Elongin-A2 (sprot)

An elongin-A2 that is encoded in the genome of human.


TEX11_HUMAN Testis-expressed protein 11 (sprot)

A testis-expressed protein 11 that is encoded in the genome of human.


LRC56_HUMAN Leucine-rich repeat-containing protein 56 (sprot)

A leucine-rich repeat-containing protein 56 that is encoded in the genome of human.


ZZZ3_HUMAN ZZ-type zinc finger-containing protein 3 (sprot)

A ZZ-type zinc finger-containing protein 3 that is encoded in the genome of human.


SHLD1_HUMAN Shieldin complex subunit 1 (sprot)

A shieldin complex subunit 1 that is encoded in the genome of human.


EXOC8_HUMAN Exocyst complex component 8 (sprot)

An exocyst complex component 8 that is encoded in the genome of human.


ZN440_HUMAN Zinc finger protein 440 (sprot)

A zinc finger protein 440 that is encoded in the genome of human.


PIANP_HUMAN PILR alpha-associated neural protein (sprot)

A PILR alpha-associated neural protein that is encoded in the genome of human.


CPNE9_HUMAN Copine-9 (sprot)

A copine-9 that is encoded in the genome of human.


CJ067_HUMAN Uncharacterized protein C10orf67, mitochondrial (sprot)

A protein that is a translation product of the C10orf67 gene in human.


SYTL1_HUMAN Synaptotagmin-like protein 1 (sprot)

A synaptotagmin-like protein 1 that is encoded in the genome of human.


TEKL1_HUMAN Tektin-like protein 1 (sprot)

A coiled-coil domain-containing protein 105 that is encoded in the genome of human.


GT252_HUMAN Procollagen galactosyltransferase 2 (sprot)

A procollagen galactosyltransferase 2 that is encoded in the genome of human.


REM2_HUMAN GTP-binding protein REM 2 (sprot)

A GTP-binding protein REM 2 that is encoded in the genome of human.


TRM44_HUMAN Probable tRNA (uracil-O(2)-)-methyltransferase (sprot)

A probable tRNA (uracil-O(2)-)-methyltransferase that is encoded in the genome of human.


CA174_HUMAN UPF0688 protein C1orf174 (sprot)

A UPF0688 protein C1orf174 that is encoded in the genome of human.


PSYR_HUMAN Psychosine receptor (sprot)

A psychosine receptor that is encoded in the genome of human.


F186B_HUMAN Protein FAM186B (sprot)

A protein FAM186B that is encoded in the genome of human.


SEP12_HUMAN Septin-12 (sprot)

A septin-12 that is encoded in the genome of human.


SLN12_HUMAN Ribonuclease SLFN12 (sprot)

A ribonuclease SLFN12 that is encoded in the genome of human.


TRI22_HUMAN E3 ubiquitin-protein ligase TRIM22 (sprot)

An E3 ubiquitin-protein ligase TRIM22 that is encoded in the genome of human.


ZN100_HUMAN Zinc finger protein 100 (sprot)

A zinc finger protein 100 that is encoded in the genome of human.


TCAL8_HUMAN Transcription elongation factor A protein-like 8 (sprot)

A transcription elongation factor A protein-like 8 that is encoded in the genome of human.


PRS58_HUMAN Serine protease 58 (sprot)

A serine protease 58 that is encoded in the genome of human.


ZDH23_HUMAN Palmitoyltransferase ZDHHC23 (sprot)

A palmitoyltransferase ZDHHC23 that is encoded in the genome of human.


THNS1_HUMAN Threonine synthase-like 1 (sprot)

A threonine synthase-like 1 that is encoded in the genome of human.


CF206_HUMAN Cilia- and flagella-associated protein 206 (sprot)

A cilia- and flagella-associated protein 206 that is encoded in the genome of human.


A axonemal microtubule

A complete microtubule with 13 protofilaments that fuses with an incomplete microtubule called B tubule (containing 10 protofilaments only) to form an axonemal outer doublet. Inner and outer dynein arms, as well as the radial spoke, are attached to the A tubule.


SMYD4_HUMAN SET and MYND domain-containing protein 4 (sprot)

A SET and MYND domain-containing protein 4 that is encoded in the genome of human.


TEFF1_HUMAN Tomoregulin-1 (sprot)

A tomoregulin-1 that is encoded in the genome of human.


ASTRC_HUMAN Protein Aster-C (sprot)

A protein Aster-C that is encoded in the genome of human.


P20D2_HUMAN Xaa-Arg dipeptidase (sprot)

An Xaa-Arg dipeptidase that is encoded in the genome of human.


K2013_HUMAN Uncharacterized protein KIAA2013 (sprot)

An uncharacterized protein KIAA2013 that is encoded in the genome of human.


DAAF8_HUMAN Dynein axonemal assembly factor 8 (sprot)

A dynein axonemal assembly factor 8 that is encoded in the genome of human.


OSCAR_HUMAN Osteoclast-associated immunoglobulin-like receptor (sprot)

An osteoclast-associated immunoglobulin-like receptor that is encoded in the genome of human.


BD1L2_HUMAN Biorientation of chromosomes in cell division protein 1-like 2 (sprot)

A protein that is a translation product of the BOD1L2 gene in human.


GAR4_HUMAN Golgi-associated RAB2 interactor protein 4 (sprot)

A Golgi-associated RAB2 interactor protein 4 that is encoded in the genome of human.


CMTR2_HUMAN Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2 (sprot)

A cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2 that is encoded in the genome of human.


Catalysis of the reaction: S-adenosyl-L-methionine + m7G(5')pppR-RNA = S-adenosyl-L-homocysteine + m7G(5')pppRm-RNA. R may be guanosine or adenosine.


CC170_HUMAN Coiled-coil domain-containing protein 170 (sprot)

A coiled-coil domain-containing protein 170 that is encoded in the genome of human.


KATL2_HUMAN Katanin p60 ATPase-containing subunit A-like 2 (sprot)

A katanin p60 ATPase-containing subunit A-like 2 that is encoded in the genome of human.


ULK2_HUMAN Serine/threonine-protein kinase ULK2 (sprot)

A serine/threonine-protein kinase ULK2 that is encoded in the genome of human.


HACE1_HUMAN E3 ubiquitin-protein ligase HACE1 (sprot)

An E3 ubiquitin-protein ligase HACE1 that is encoded in the genome of human.


UBQLN_HUMAN Ubiquilin-like protein (sprot)

A ubiquilin-like protein that is encoded in the genome of human.


MICU2_HUMAN Calcium uptake protein 2, mitochondrial (sprot)

A calcium uptake protein 2, mitochondrial that is encoded in the genome of human.


IZUM1_HUMAN Izumo sperm-egg fusion protein 1 (sprot)

An izumo sperm-egg fusion protein 1 that is encoded in the genome of human.


CFA46_HUMAN Cilia- and flagella-associated protein 46 (sprot)

A cilia- and flagella-associated protein 46 that is encoded in the genome of human.


ENTD1_HUMAN ENTH domain-containing protein 1 (sprot)

An ENTH domain-containing protein 1 that is encoded in the genome of human.


RN168_HUMAN E3 ubiquitin-protein ligase RNF168 (sprot)

An E3 ubiquitin-protein ligase RNF168 that is encoded in the genome of human.


histone H2AK15 ubiquitin ligase activity

Catalysis of the transfer of a ubiquitin molecule to histone 2A at the lysine-15 residue.


ZN679_HUMAN Zinc finger protein 679 (sprot)

A zinc finger protein 679 that is encoded in the genome of human.


TBC21_HUMAN TBC1 domain family member 21 (sprot)

A TBC1 domain family member 21 that is encoded in the genome of human.


CC116_HUMAN Coiled-coil domain-containing protein 116 (sprot)

A coiled-coil domain-containing protein 116 that is encoded in the genome of human.


DND1_HUMAN Dead end protein homolog 1 (sprot)

A dead end protein homolog 1 that is encoded in the genome of human.


SAXO1_HUMAN Stabilizer of axonemal microtubules 1 (sprot)

A stabilizer of axonemal microtubules 1 that is encoded in the genome of human.


CE57L_HUMAN Centrosomal protein CEP57L1 (sprot)

A centrosomal protein CEP57L1 that is encoded in the genome of human.


DZI1L_HUMAN Cilium assembly protein DZIP1L (sprot)

A cilium assembly protein DZIP1L that is encoded in the genome of human.


ciliary transition zone assembly

The aggregation, arrangement and bonding together of a set of components to form a ciliary transition zone.


LRC34_HUMAN Leucine-rich repeat-containing protein 34 (sprot)

A leucine-rich repeat-containing protein 34 that is encoded in the genome of human.


AN13A_HUMAN Ankyrin repeat domain-containing protein 13A (sprot)

An ankyrin repeat domain-containing protein 13A that is encoded in the genome of human.


negative regulation of protein localization to endosome

Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to endosome.


GP135_HUMAN G-protein coupled receptor 135 (sprot)

A G-protein coupled receptor 135 that is encoded in the genome of human.


F200C_HUMAN Protein FAM200C (sprot)

A protein that is a translation product of the ZBED8 gene in human.


SACDR_HUMAN Sperm acrosome developmental regulator (sprot)

A sperm acrosome developmental regulator that is encoded in the genome of human.


ZN683_HUMAN Tissue-resident T-cell transcription regulator protein ZNF683 (sprot)

A tissue-resident T-cell transcription regulator protein ZNF683 that is encoded in the genome of human.


regulation of natural killer cell differentiation involved in immune response

Any process that modulates the frequency, rate or extent of natural killer cell differentiation as part of an immune response.


PHAR4_HUMAN Phosphatase and actin regulator 4 (sprot)

A phosphatase and actin regulator 4 that is encoded in the genome of human.


ZNF34_HUMAN Zinc finger protein 34 (sprot)

A zinc finger protein 34 that is encoded in the genome of human.


RCOR2_HUMAN REST corepressor 2 (sprot)

A REST corepressor 2 that is encoded in the genome of human.


RASEF_HUMAN Ras and EF-hand domain-containing protein (sprot)

A RAS and EF-hand domain-containing protein that is encoded in the genome of human.


CHSS2_HUMAN Chondroitin sulfate synthase 2 (sprot)

A chondroitin sulfate synthase 2 that is encoded in the genome of human.


NRSN1_HUMAN Neurensin-1 (sprot)

A neurensin-1 that is encoded in the genome of human.


TRM2A_HUMAN tRNA (uracil-5-)-methyltransferase homolog A (sprot)

A tRNA (uracil-5-)-methyltransferase homolog A that is encoded in the genome of human.


C-methyltransferase activity

Catalysis of the transfer of a methyl group to the carbon atom of an acceptor molecule.


S-adenosylmethionine-dependent tRNA (m5U54) methyltransferase activity

Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing thymine at position U54 of a transfer RNA. This occurs in most Gram-negative bacteria, some archae, and eukaryotes.


RUSD2_HUMAN Pseudouridylate synthase RPUSD2 (sprot)

A pseudouridylate synthase RPUSD2 that is encoded in the genome of human.


ELMD2_HUMAN ELMO domain-containing protein 2 (sprot)

An ELMO domain-containing protein 2 that is encoded in the genome of human.


A16A1_HUMAN Aldehyde dehydrogenase family 16 member A1 (sprot)

An aldehyde dehydrogenase family 16 member A1 that is encoded in the genome of human.


CKLF1_HUMAN CKLF-like MARVEL transmembrane domain-containing protein 1 (sprot)

A CKLF-like MARVEL transmembrane domain-containing protein 1 that is encoded in the genome of human.


K319L_HUMAN Dyslexia-associated protein KIAA0319-like protein (sprot)

A dyslexia-associated protein KIAA0319-like protein that is encoded in the genome of human.


H18_HUMAN Histone H1.8 (sprot)

A histone H1.8 that is encoded in the genome of human.


RTKN2_HUMAN Rhotekin-2 (sprot)

A rhotekin-2 that is encoded in the genome of human.


CORA1_HUMAN Collagen alpha-1(XXVII) chain (sprot)

A collagen alpha-1(XXVII) chain that is encoded in the genome of human.


growth plate cartilage chondrocyte development

The progression of a growth plate cartilage chondrocyte over time from after its fate commitment to the mature cell.


ZN101_HUMAN Zinc finger protein 101 (sprot)

A zinc finger protein 101 that is encoded in the genome of human.


KMT2E_HUMAN Inactive histone-lysine N-methyltransferase 2E (sprot)

A histone-lysine N-methyltransferase 2E that is encoded in the genome of human.


DCP1B_HUMAN mRNA-decapping enzyme 1B (sprot)

An mRNA-decapping enzyme 1B that is encoded in the genome of human.


S22AF_HUMAN Solute carrier family 22 member 15 (sprot)

A solute carrier family 22 member 15 that is encoded in the genome of human.


amino-acid betaine transport

The directed movement of betaine, the N-trimethyl derivative of an amino acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


DOCK3_HUMAN Dedicator of cytokinesis protein 3 (sprot)

A dedicator of cytokinesis protein 3 that is encoded in the genome of human.


PACE1_HUMAN Protein-associating with the carboxyl-terminal domain of ezrin (sprot)

A protein-associating with the carboxyl-terminal domain of ezrin that is encoded in the genome of human.


NALCN_HUMAN Sodium leak channel NALCN (sprot)

A sodium leak channel NALCN that is encoded in the genome of human.


AGRF5_HUMAN Adhesion G protein-coupled receptor F5 (sprot)

An adhesion G protein-coupled receptor F5 that is encoded in the genome of human.


AGRF4_HUMAN Adhesion G protein-coupled receptor F4 (sprot)

An adhesion G protein-coupled receptor F4 that is encoded in the genome of human.


AGRG5_HUMAN Adhesion G-protein coupled receptor G5 (sprot)

An adhesion G-protein coupled receptor G5 that is encoded in the genome of human.


AGRF3_HUMAN Adhesion G-protein coupled receptor F3 (sprot)

An adhesion G-protein coupled receptor F3 that is encoded in the genome of human.


AGRG4_HUMAN Adhesion G-protein coupled receptor G4 (sprot)

An adhesion G-protein coupled receptor G4 that is encoded in the genome of human.


AGRF2_HUMAN Putative adhesion G protein-coupled receptor F2P (sprot)

An adhesion G-protein coupled receptor F2 that is encoded in the genome of human.


XRN1_HUMAN 5'-3' exoribonuclease 1 (sprot)

A 5'-3' exoribonuclease 1 that is encoded in the genome of human.


cellular response to puromycin

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a puromycin stimulus.


IFNL3_HUMAN Interferon lambda-3 (sprot)

An interleukin-28B that is encoded in the genome of human.


IFNL2_HUMAN Interferon lambda-2 (sprot)

An interleukin-28A that is encoded in the genome of human.


UNC5B_HUMAN Netrin receptor UNC5B (sprot)

A netrin receptor UNC5B that is encoded in the genome of human.


CPMD8_HUMAN C3 and PZP-like alpha-2-macroglobulin domain-containing protein 8 (sprot)

A C3 and PZP-like alpha-2-macroglobulin domain-containing protein 8 that is encoded in the genome of human.


RGDSR_HUMAN Ral-GDS-related protein (sprot)

A Ral-GDS-related protein that is encoded in the genome of human.


TDH_HUMAN Inactive L-threonine 3-dehydrogenase, mitochondrial (sprot)

An inactive L-threonine 3-dehydrogenase, mitochondrial that is encoded in the genome of human.


MCLN2_HUMAN Mucolipin-2 (sprot)

A mucolipin-2 that is encoded in the genome of human.


positive regulation of macrophage inflammatory protein 1 alpha production

Any process that activates or increases the frequency, rate, or extent of production of macrophage inflammatory protein 1 alpha.


MAML2_HUMAN Mastermind-like protein 2 (sprot)

A mastermind-like protein 2 that is encoded in the genome of human.


PELP1_HUMAN Proline-, glutamic acid- and leucine-rich protein 1 (sprot)

A proline-, glutamic acid- and leucine-rich protein 1 that is encoded in the genome of human.


CDK20_HUMAN Cyclin-dependent kinase 20 (sprot)

A cyclin-dependent kinase 20 that is encoded in the genome of human.


regulation of protein maturation

Any process that modulates the frequency, rate or extent of protein maturation.


ZN654_HUMAN Zinc finger protein 654 (sprot)

A zinc finger protein 654 that is encoded in the genome of human.


S38A6_HUMAN Probable sodium-coupled neutral amino acid transporter 6 (sprot)

A probable sodium-coupled neutral amino acid transporter 6 that is encoded in the genome of human.


ZDH14_HUMAN Palmitoyltransferase ZDHHC14 (sprot)

A palmitoyltransferase ZDHHC14 that is encoded in the genome of human.


D107A_HUMAN Beta-defensin 107 (sprot)

A beta-defensin 107 that is encoded in the genome of human.


ABI1_HUMAN Abl interactor 1 (sprot)

An Abl interactor 1 that is encoded in the genome of human.


TBC3A_HUMAN TBC1 domain family member 3 (sprot)

A TBC1 domain family member 3 that is encoded in the genome of human.


ST134_HUMAN Putative protein FAM10A4 (sprot)


R113B_HUMAN RING finger protein 113B (sprot)

A RING finger protein 113B that is encoded in the genome of human.


H6ST3_HUMAN Heparan-sulfate 6-O-sulfotransferase 3 (sprot)

A heparan-sulfate 6-O-sulfotransferase 3 that is encoded in the genome of human.


AGRG2_HUMAN Adhesion G-protein coupled receptor G2 (sprot)

An adhesion G-protein coupled receptor G2 that is encoded in the genome of human.


WDFY3_HUMAN WD repeat and FYVE domain-containing protein 3 (sprot)

A WD repeat and FYVE domain-containing protein 3 that is encoded in the genome of human.


SELH_HUMAN Selenoprotein H (sprot)

A selenoprotein H that is encoded in the genome of human.


MYCD_HUMAN Myocardin (sprot)

A myocardin that is encoded in the genome of human.


regulation of cell growth by extracellular stimulus

Any process in which external signals modulate the frequency, rate or extent of cell growth, the irreversible increase in size of a cell over time.


cellular component maintenance

The organization process that preserves a cellular component in a stable functional or structural state.


regulation of phenotypic switching

Any process that modulates the frequency, rate or extent of phenotypic switching.


negative regulation of skeletal muscle cell differentiation

Any process that stops, prevents or reduces the frequency, rate or extent of skeletal muscle cell differentiation.


CKLF4_HUMAN CKLF-like MARVEL transmembrane domain-containing protein 4 (sprot)

A CKLF-like MARVEL transmembrane domain-containing protein 4 that is encoded in the genome of human.


OFCC1_HUMAN Orofacial cleft 1 candidate gene 1 protein (sprot)

An orofacial cleft 1 candidate gene 1 protein that is encoded in the genome of human.


DYLT2_HUMAN Dynein light chain Tctex-type protein 2 (sprot)

A dynein light chain Tctex-type protein 2 that is encoded in the genome of human.


CLCL1_HUMAN Putative C-type lectin-like domain family 1 (sprot)

A putative C-type lectin-like domain family 1 that is encoded in the genome of human.


B cell adhesion

The attachment of a B cell to another cell via adhesion molecules.


CA2D3_HUMAN Voltage-dependent calcium channel subunit alpha-2/delta-3 (sprot)

A voltage-dependent calcium channel subunit alpha-2/delta-3 that is encoded in the genome of human.


ASPM_HUMAN Abnormal spindle-like microcephaly-associated protein (sprot)

An abnormal spindle-like microcephaly-associated protein that is encoded in the genome of human.


forebrain neuroblast division

The division of a neuroblast located in the forebrain. Neuroblast division gives rise to at least another neuroblast.


negative regulation of asymmetric cell division

Any process that stops, prevents, or reduces the frequency, rate or extent of asymmetric cell division.


HS3S5_HUMAN Heparan sulfate glucosamine 3-O-sulfotransferase 5 (sprot)

A heparan sulfate glucosamine 3-O-sulfotransferase 5 that is encoded in the genome of human.


protein sulfation

The addition of a sulfate group as an ester to a protein amino acid.


FAM9C_HUMAN Protein FAM9C (sprot)

A protein FAM9C that is encoded in the genome of human.


FAM9B_HUMAN Protein FAM9B (sprot)

A protein FAM9B that is encoded in the genome of human.


FAM9A_HUMAN Protein FAM9A (sprot)

A protein FAM9A that is encoded in the genome of human.


SYCP3_HUMAN Synaptonemal complex protein 3 (sprot)

A synaptonemal complex protein 3 that is encoded in the genome of human.


DSEL_HUMAN Dermatan-sulfate epimerase-like protein (sprot)

A dermatan-sulfate epimerase-like protein that is encoded in the genome of human.


Catalysis of the reaction: chondroitin D-glucuronate = dermatan L-iduronate.


dermatan sulfate biosynthetic process

The chemical reactions and pathways resulting in the formation of dermatan sulfate, any glycosaminoglycan with repeats consisting of beta-(1,4)-linked L-iduronyl-beta-(1,3)-N-acetyl-D-galactosamine 4-sulfate units.


KIRR3_HUMAN Kin of IRRE-like protein 3 (sprot)

A kin of IRRE-like protein 3 that is encoded in the genome of human.


inter-male aggressive behavior

Aggressive behavior based on competition between males of the same species over access to resources such as females, dominance, status, etc. and characterized by noise, threats, and is often less injurious.


CKLF8_HUMAN CKLF-like MARVEL transmembrane domain-containing protein 8 (sprot)

A CKLF-like MARVEL transmembrane domain-containing protein 8 that is encoded in the genome of human.


RDH10_HUMAN Retinol dehydrogenase 10 (sprot)

A retinol dehydrogenase 10 that is encoded in the genome of human.


primary lung bud formation

The morphogenetic process in which the foregut region specified to become the lung forms the initial left and right buds.


positive regulation of retinoic acid biosynthetic process

Any process that activates or increases the frequency, rate or extent of retinoic acid biosynthetic process.


TENS4_HUMAN Tensin-4 (sprot)

A tensin-4 that is encoded in the genome of human.


TAF1L_HUMAN Transcription initiation factor TFIID subunit 1-like (sprot)

A transcription initiation factor TFIID 210 kDa subunit that is encoded in the genome of human.


ABCA7_HUMAN Phospholipid-transporting ATPase ABCA7 (sprot)

A phospholipid-transporting ATPase ABCA7 that is encoded in the genome of human.


negative regulation of amyloid precursor protein biosynthetic process

Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of amyloid precursor protein (APP), the precursor of amyloid-beta.


positive regulation of engulfment of apoptotic cell

Any process that activates or increases the frequency, rate or extent of engulfment of apoptotic cell.


BLID_HUMAN BH3-like motif-containing cell death inducer (sprot)

A BH3-like motif-containing cell death inducer that is encoded in the genome of human.


APCD1_HUMAN Protein APCDD1 (sprot)

A protein APCDD1 that is encoded in the genome of human.


LAT1N_HUMAN Putative L-type amino acid transporter 1-like protein MLAS (sprot)


SYCE1_HUMAN Synaptonemal complex central element protein 1 (sprot)

A synaptonemal complex central element protein 1 that is encoded in the genome of human.


CENPL_HUMAN Centromere protein L (sprot)

A centromere protein L that is encoded in the genome of human.


RBIS_HUMAN Ribosomal biogenesis factor (sprot)

A ribosomal biogenesis factor that is encoded in the genome of human.


TMM61_HUMAN Transmembrane protein 61 (sprot)

A transmembrane protein 61 that is encoded in the genome of human.


F185A_HUMAN Protein FAM185A (sprot)

A protein FAM185A that is encoded in the genome of human.


CF218_HUMAN Putative uncharacterized protein encoded by LINC00518 (sprot)

A putative uncharacterized protein encoded by LINC00518 that is encoded in the genome of human.


VKORL_HUMAN Vitamin K epoxide reductase complex subunit 1-like protein 1 (sprot)

A vitamin K epoxide reductase complex subunit 1-like protein 1 that is encoded in the genome of human.


vitamin-K-epoxide reductase (warfarin-sensitive) activity

Catalysis of the reaction: phylloquinol + a protein with a disulfide bond = phylloquinone + a protein with reduced L-cysteine residues.


peptidyl-glutamic acid carboxylation

The gamma-carboxylation of peptidyl-glutamic acid; catalyzed by the vitamin K dependent gamma-glutamyl carboxylase.


RBFA_HUMAN Putative ribosome-binding factor A, mitochondrial (sprot)

A putative ribosome-binding factor A, mitochondrial that is encoded in the genome of human.


LGI2_HUMAN Leucine-rich repeat LGI family member 2 (sprot)

A leucine-rich repeat LGI family member 2 that is encoded in the genome of human.


GNT2A_HUMAN N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase (sprot)

An N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase that is encoded in the genome of human.


FCSK_HUMAN L-fucose kinase (sprot)

An L-fucose kinase that is encoded in the genome of human.


fucokinase activity

Catalysis of the reaction: L-fucose + ATP = beta-L-fucose 1-phosphate + ADP + 2 H+.


GDP-L-fucose salvage

The formation of GDP-L-fucose from L-fucose, without de novo synthesis. L-fucose is phosphorylated by fucokinase and then converted by fucose-1-phosphate guanylyltransferase (EC:2.7.7.30).


NLGNX_HUMAN Neuroligin-4, X-linked (sprot)

A neuroligin-4, X-linked that is encoded in the genome of human.


symmetric, GABA-ergic, inhibitory synapse

A neuron to neuron synapse that lacks an electron dense postsynaptic specialization, uses GABA as a neurotransmitter and whose activity results in inhibitory postsynaptic potentials.


FMR1N_HUMAN FMR1 neighbor protein (sprot)

An FMR1 neighbor protein that is encoded in the genome of human.


SPG16_HUMAN Sperm-associated antigen 16 protein (sprot)

A sperm-associated antigen 16 protein that is encoded in the genome of human.


CLYBL_HUMAN Citramalyl-CoA lyase, mitochondrial (sprot)

A citramalyl-CoA lyase, mitochondrial that is encoded in the genome of human.


malate synthase activity

Catalysis of the reaction: acetyl-CoA + glyoxylate + H2O = (S)-malate + CoA + H+.


(S)-citramalyl-CoA lyase activity

Catalysis of the reaction: (3S)-citramalyl-CoA = acetyl-CoA + pyruvate.


regulation of cobalamin metabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom.


positive regulation of cobalamin metabolic process

Any process that activates or increases the frequency, rate or extent of a cobalamin metabolic process.


SPART_HUMAN Spartin (sprot)

A spartin that is encoded in the genome of human.


negative regulation of collateral sprouting in absence of injury

Any process that stops, prevents, or reduces the frequency, rate or extent of collateral sprouting in the absence of injury.


ZN444_HUMAN Zinc finger protein 444 (sprot)

A zinc finger protein 444 that is encoded in the genome of human.


OR4N4_HUMAN Olfactory receptor 4N4 (sprot)

An olfactory receptor 4N4 that is encoded in the genome of human.


OR8I2_HUMAN Olfactory receptor 8I2 (sprot)

An olfactory receptor 8I2 that is encoded in the genome of human.


PGAM4_HUMAN Probable phosphoglycerate mutase 4 (sprot)

A probable phosphoglycerate mutase 4 that is encoded in the genome of human.


ABRA_HUMAN Actin-binding Rho-activating protein (sprot)

An actin-binding Rho-activating protein that is encoded in the genome of human.


SPICE_HUMAN Spindle and centriole-associated protein 1 (sprot)

A spindle and centriole-associated protein 1 that is encoded in the genome of human.


TTC5_HUMAN Tetratricopeptide repeat protein 5 (sprot)

A tetratricopeptide repeat protein 5 that is encoded in the genome of human.


PUSL1_HUMAN tRNA pseudouridine synthase-like 1 (sprot)

A tRNA pseudouridine synthase-like 1 that is encoded in the genome of human.


ATOH7_HUMAN Transcription factor ATOH7 (sprot)

A transcription factor ATOH7 that is encoded in the genome of human.


positive regulation of retinal ganglion cell axon guidance

Any process that activates or increases the frequency, rate or extent of retinal ganglion cell axon guidance.


TAGAP_HUMAN T-cell activation Rho GTPase-activating protein (sprot)

A T-cell activation Rho GTPase-activating protein that is encoded in the genome of human.


D106A_HUMAN Beta-defensin 106 (sprot)

A beta-defensin 106 that is encoded in the genome of human.


MIER1_HUMAN Mesoderm induction early response protein 1 (sprot)

A mesoderm induction early response protein 1 that is encoded in the genome of human.


CEND_HUMAN Cell cycle exit and neuronal differentiation protein 1 (sprot)

A cell cycle exit and neuronal differentiation protein 1 that is encoded in the genome of human.


LSME2_HUMAN Leucine-rich single-pass membrane protein 2 (sprot)

A protein that is a translation product of the LSMEM2 gene in human.


SHSA5_HUMAN Protein shisa-5 (sprot)

A protein shisa-5 that is encoded in the genome of human.


CP4X1_HUMAN Cytochrome P450 4X1 (sprot)

A cytochrome P450 4X1 that is encoded in the genome of human.


MMP21_HUMAN Matrix metalloproteinase-21 (sprot)

A matrix metalloproteinase-21 that is encoded in the genome of human.


RPTOR_HUMAN Regulatory-associated protein of mTOR (sprot)

A regulatory-associated protein of mTOR that is encoded in the genome of human.


CADM3_HUMAN Cell adhesion molecule 3 (sprot)

A cell adhesion molecule 3 that is encoded in the genome of human.


O5AS1_HUMAN Olfactory receptor 5AS1 (sprot)

An olfactory receptor 5AS1 that is encoded in the genome of human.


CNPY4_HUMAN Protein canopy homolog 4 (sprot)

A protein canopy homolog 4 that is encoded in the genome of human.


NPT2C_HUMAN Sodium-dependent phosphate transport protein 2C (sprot)

A sodium-dependent phosphate transport protein 2C that is encoded in the genome of human.


PORIM_HUMAN Porimin (sprot)

A porimin that is encoded in the genome of human.


LGI4_HUMAN Leucine-rich repeat LGI family member 4 (sprot)

A leucine-rich repeat LGI family member 4 that is encoded in the genome of human.


DAW1_HUMAN Dynein assembly factor with WD repeat domains 1 (sprot)

A dynein assembly factor with WDR repeat domains 1 that is encoded in the genome of human.


CNTRB_HUMAN Centrobin (sprot)

A centrobin that is encoded in the genome of human.


ORML3_HUMAN ORM1-like protein 3 (sprot)

An ORM1-like protein 3 that is encoded in the genome of human.


ABCA6_HUMAN ATP-binding cassette sub-family A member 6 (sprot)

An ATP-binding cassette sub-family A member 6 that is encoded in the genome of human.


EID3_HUMAN EP300-interacting inhibitor of differentiation 3 (sprot)

An EP300-interacting inhibitor of differentiation 3 that is encoded in the genome of human.


ZFP82_HUMAN Zinc finger protein 82 homolog (sprot)

A zinc finger protein 82 that is encoded in the genome of human.


PURA1_HUMAN Adenylosuccinate synthetase isozyme 1 (sprot)

An adenylosuccinate synthetase isozyme 1 that is encoded in the genome of human.


BCL6B_HUMAN B-cell CLL/lymphoma 6 member B protein (sprot)

A B-cell CLL/lymphoma 6 member B protein that is encoded in the genome of human.


CXD3_HUMAN Gap junction delta-3 protein (sprot)

A gap junction delta-3 protein that is encoded in the genome of human.


negative regulation of cardiac conduction

Any process that stops, prevents or reduces the frequency, rate or extent of cardiac conduction.


LGI3_HUMAN Leucine-rich repeat LGI family member 3 (sprot)

A leucine-rich repeat LGI family member 3 that is encoded in the genome of human.


OR8H3_HUMAN Olfactory receptor 8H3 (sprot)

An olfactory receptor 8H3 that is encoded in the genome of human.


OR6V1_HUMAN Olfactory receptor 6V1 (sprot)

An olfactory receptor 6V1 that is encoded in the genome of human.


LIRA2_HUMAN Leukocyte immunoglobulin-like receptor subfamily A member 2 (sprot)

A leukocyte immunoglobulin-like receptor subfamily A member 2 that is encoded in the genome of human.


innate immune response activating cell surface receptor signaling pathway

biolink:Pathway biolink:BiologicalProcess biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:OntologyClass biolink:Occurrent biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

The series of molecular signals initiated by a ligand binding to a cell surface receptor that leads to the activation of an innate immune response.


AHI1_HUMAN Jouberin (sprot)

A jouberin that is encoded in the genome of human.


positive regulation of polarized epithelial cell differentiation

Any process that activates or increases the rate or extent of polarized epithelial cell differentiation.


cloaca development

The process whose specific outcome is the progression of the cloaca over time, from it's formation to the mature structure. The cloaca is the common chamber into which intestinal, genital and urinary canals open in vertebrates.


pronephric nephron tubule morphogenesis

The process in which the anatomical structures of a pronephric nephron tubule are generated and organized from an epithelium. A pronephric nephron tubule is an epithelial tube that is part of the pronephric nephron.


GPC2_HUMAN Glypican-2 (sprot)

A glypican-2 that is encoded in the genome of human.


NAGS_HUMAN N-acetylglutamate synthase, mitochondrial (sprot)

An N-acetylglutamate synthase, mitochondrial that is encoded in the genome of human.


Catalysis of the reaction: L-glutamate + acetyl-CoA = N-acetyl-L-glutamate + CoA + H+.


methione N-acyltransferase activity

Catalysis of the reaction: L-methionine + acetyl-CoA = N-acetyl-L-methionine + coenzyme A + H+.


OR8H2_HUMAN Olfactory receptor 8H2 (sprot)

An olfactory receptor 8H2 that is encoded in the genome of human.


CCAR2_HUMAN Cell cycle and apoptosis regulator protein 2 (sprot)

A cell cycle and apoptosis regulator protein 2 that is encoded in the genome of human.


PDK1L_HUMAN Serine/threonine-protein kinase PDIK1L (sprot)

A serine/threonine-protein kinase PDIK1L that is encoded in the genome of human.


NDUF2_HUMAN NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2 (sprot)

An NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2 that is encoded in the genome of human.


ZN567_HUMAN Zinc finger protein 567 (sprot)

A zinc finger protein 567 that is encoded in the genome of human.


CARTF_HUMAN Calcium-responsive transcription factor (sprot)

A calcium-responsive transcription factor that is encoded in the genome of human.


SIX5_HUMAN Homeobox protein SIX5 (sprot)

A homeobox protein SIX5 that is encoded in the genome of human.


KT222_HUMAN Keratin-like protein KRT222 (sprot)

A keratin-like protein KRT222 that is encoded in the genome of human.


CD033_HUMAN UPF0462 protein C4orf33 (sprot)

A UPF0462 protein C4orf33 that is encoded in the genome of human.


CCNQ_HUMAN Cyclin-Q (sprot)

A cyclin-Q that is encoded in the genome of human.


VPS52_HUMAN Vacuolar protein sorting-associated protein 52 homolog (sprot)

A vacuolar protein sorting-associated protein 52 that is encoded in the genome of human.


embryonic ectodermal digestive tract development

The process, occurring during the embryonic phase, whose specific outcome is the progression of the ectodermal gut over time, from its formation to the mature structure.


GBRG1_HUMAN Gamma-aminobutyric acid receptor subunit gamma-1 (sprot)

A gamma-aminobutyric acid receptor subunit gamma-1 that is encoded in the genome of human.


BWR1B_HUMAN Beckwith-Wiedemann syndrome chromosomal region 1 candidate gene B protein (sprot)

A Beckwith-Wiedemann syndrome chromosomal region 1 candidate gene B protein that is encoded in the genome of human.


CF107_HUMAN Cilia- and flagella-associated protein 107 (sprot)

An uncharacterized protein C1orf158 that is encoded in the genome of human.


LYG1_HUMAN Lysozyme g-like protein 1 (sprot)

A lysozyme g-like protein 1 that is encoded in the genome of human.


FXL14_HUMAN F-box/LRR-repeat protein 14 (sprot)

An F-box/LRR-repeat protein 14 that is encoded in the genome of human.


NUP93_HUMAN Nuclear pore complex protein Nup93 (sprot)

A nuclear pore complex protein Nup93 that is encoded in the genome of human.


S11IP_HUMAN Serine/threonine-protein kinase 11-interacting protein (sprot)

A serine/threonine-protein kinase 11-interacting protein that is encoded in the genome of human.


ZN687_HUMAN Zinc finger protein 687 (sprot)

A zinc finger protein 687 that is encoded in the genome of human.


REXO1_HUMAN RNA exonuclease 1 homolog (sprot)

An RNA exonuclease 1 that is encoded in the genome of human.


CMTR1_HUMAN Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1 (sprot)

A cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1 that is encoded in the genome of human.


LRC47_HUMAN Leucine-rich repeat-containing protein 47 (sprot)

A leucine-rich repeat-containing protein 47 that is encoded in the genome of human.


S6OS1_HUMAN Protein SIX6OS1 (sprot)

A protein SIX6OS1 that is encoded in the genome of human.


meiotic DNA double-strand break processing involved in reciprocal meiotic recombination

The cell cycle process in which the 5' to 3' exonucleolytic resection of the DNA at the site of the break to form a 3' single-strand DNA overhang occurs resulting in double strand break formation and repair through a double Holliday junction intermediate.


DOCK4_HUMAN Dedicator of cytokinesis protein 4 (sprot)

A dedicator of cytokinesis protein 4 that is encoded in the genome of human.


THMS1_HUMAN Protein THEMIS (sprot)

A protein THEMIS that is encoded in the genome of human.


positive T cell selection

The process of sparing immature T cells which react with self-MHC protein complexes with low affinity levels from apoptotic death.


negative T cell selection

The process of elimination of immature T cells which react strongly with self-antigens.


CP4Z2_HUMAN Putative inactive cytochrome P450 family member 4Z2 (sprot)


BATF2_HUMAN Basic leucine zipper transcriptional factor ATF-like 2 (sprot)

A basic leucine zipper transcriptional factor ATF-like 2 that is encoded in the genome of human.


BEST3_HUMAN Bestrophin-3 (sprot)

A bestrophin-3 that is encoded in the genome of human.


ligand-gated monoatomic anion channel activity

Enables the transmembrane transfer of an inorganic anion by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts.


negative regulation of monoatomic ion transport

Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


CLC4F_HUMAN C-type lectin domain family 4 member F (sprot)

A C-type lectin domain family 4 member F that is encoded in the genome of human.


DYNAP_HUMAN Dynactin-associated protein (sprot)

A protein that is a translation product of the DYNAP gene in human.


cellular response to ergosterol

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ergosterol stimulus.


K2C78_HUMAN Keratin, type II cytoskeletal 78 (sprot)

A keratin, type II cytoskeletal 78 that is encoded in the genome of human.


CRBG2_HUMAN Beta/gamma crystallin domain-containing protein 2 (sprot)

A beta/gamma crystallin domain-containing protein 2 that is encoded in the genome of human.


CAH13_HUMAN Carbonic anhydrase 13 (sprot)

A carbonic anhydrase 13 that is encoded in the genome of human.


THEM5_HUMAN Acyl-coenzyme A thioesterase THEM5 (sprot)

An acyl-coenzyme A thioesterase THEM5 that is encoded in the genome of human.


S39AB_HUMAN Zinc transporter ZIP11 (sprot)

A zinc transporter ZIP11 that is encoded in the genome of human.


MYO1H_HUMAN Unconventional myosin-Ih (sprot)

A myosin-Ih that is encoded in the genome of human.


CFA52_HUMAN Cilia- and flagella-associated protein 52 (sprot)

A cilia- and flagella-associated protein 52 that is encoded in the genome of human.


ARG28_HUMAN Rho guanine nucleotide exchange factor 28 (sprot)

A Rho guanine nucleotide exchange factor 28 that is encoded in the genome of human.


ZN710_HUMAN Zinc finger protein 710 (sprot)

A zinc finger protein 710 that is encoded in the genome of human.


YI025_HUMAN Putative uncharacterized protein FLJ37218 (sprot)


INT1_HUMAN Integrator complex subunit 1 (sprot)

An integrator complex subunit 1 that is encoded in the genome of human.


SYNE4_HUMAN Nesprin-4 (sprot)

A nesprin-4 that is encoded in the genome of human.


KLH34_HUMAN Kelch-like protein 34 (sprot)

A kelch-like protein 34 that is encoded in the genome of human.


H2B3B_HUMAN Histone H2B type 3-B (sprot)

A histone H2B type 3-B that is encoded in the genome of human.


RHG24_HUMAN Rho GTPase-activating protein 24 (sprot)

A Rho GTPase-activating protein 24 that is encoded in the genome of human.


PROM2_HUMAN Prominin-2 (sprot)

A prominin-2 that is encoded in the genome of human.


prominosome

An extracellular membrane-bounded vesicle that contains prominin proteins (in mouse Prom1/CD33 or Prom2) and are found in body fluids including ventricular fluid, saliva, urine and seminal fluid. In the ventricular fluid of the developing mouse brain two major classes of these particles have been observed (P2 particles of 500-1000 nm and P4 particles of 50-80 nm) which likely originate from microvilli, primary cilia and/or the midbody of neuroepithelial cells. The physiological role is not known.


GAPT_HUMAN Protein GAPT (sprot)

A protein GAPT that is encoded in the genome of human.


PLD6_HUMAN Mitochondrial cardiolipin hydrolase (sprot)

A phospholipase D6 that is encoded in the genome of human.


cardiolipin hydrolase activity

Catalysis of the hydrolysis of cardiolipin (1,3-bis(3-phosphatidyl)glycerol), releasing phosphatidic acid (PA).


P granule organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of polar granules, cytoplasmic, non-membranous RNA/protein complex aggregates in the primordial germ cells of many higher eukaryotes.


DEPD4_HUMAN DEP domain-containing protein 4 (sprot)

A DEP domain-containing protein 4 that is encoded in the genome of human.


UNC80_HUMAN Protein unc-80 homolog (sprot)

A protein unc-80 that is encoded in the genome of human.


ARM10_HUMAN Armadillo repeat-containing protein 10 (sprot)

An armadillo repeat-containing protein 10 that is encoded in the genome of human.


LYPD1_HUMAN Ly6/PLAUR domain-containing protein 1 (sprot)

An Ly6/PLAUR domain-containing protein 1 that is encoded in the genome of human.


ZCH24_HUMAN Zinc finger CCHC domain-containing protein 24 (sprot)

A zinc finger CCHC domain-containing protein 24 that is encoded in the genome of human.


GHDC_HUMAN GH3 domain-containing protein (sprot)

A GH3 domain-containing protein that is encoded in the genome of human.


PYRD2_HUMAN Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 2 (sprot)

A pyridine nucleotide-disulfide oxidoreductase domain-containing protein 2 that is encoded in the genome of human.


SYS1_HUMAN Protein SYS1 homolog (sprot)

A protein SYS1 that is encoded in the genome of human.


PELI3_HUMAN E3 ubiquitin-protein ligase pellino homolog 3 (sprot)

An E3 ubiquitin-protein ligase pellino homolog 3 that is encoded in the genome of human.


regulation of Toll signaling pathway

Any process that modulates the frequency, rate or extent of the Tl signaling pathway.


ZN619_HUMAN Zinc finger protein 619 (sprot)

A zinc finger protein 619 that is encoded in the genome of human.


STK40_HUMAN Serine/threonine-protein kinase 40 (sprot)

A serine/threonine-protein kinase 40 that is encoded in the genome of human.


ABD12_HUMAN Lysophosphatidylserine lipase ABHD12 (sprot)

A lysophosphatidylserine lipase ABHD12 that is encoded in the genome of human.


UB2J2_HUMAN Ubiquitin-conjugating enzyme E2 J2 (sprot)

A ubiquitin-conjugating enzyme E2 J2 that is encoded in the genome of human.


TM86A_HUMAN Lysoplasmalogenase TMEM86A (sprot)

A lysoplasmalogenase-like protein TMEM86A that is encoded in the genome of human.


Catalysis of the reaction: H2O + 1-(1-alkenyl)-sn-glycero-3-phosphocholine = L-1-glycero-3-phosphocholine + an aldehyde.


CLASR_HUMAN CLK4-associating serine/arginine rich protein (sprot)

A CLK4-associating serine/arginine rich protein that is encoded in the genome of human.


AN36B_HUMAN Ankyrin repeat domain-containing protein 36B (sprot)

An ankyrin repeat domain-containing protein 36B that is encoded in the genome of human.


NLGN1_HUMAN Neuroligin-1 (sprot)

A neuroligin-1 that is encoded in the genome of human.


cytoskeletal matrix organization at active zone

The assembly and arrangement of cytomatrix proteins to form complexes in the cell cortex beneath the active zone, i.e. just beneath the presynaptic plasma membrane.


cell-cell adhesion involved in synapse maturation

The attachment of the pre-synaptic cell to the post-synaptic cell via adhesion molecules that contributes to synapse maturation.


neurexin clustering involved in presynaptic membrane assembly

The receptor clustering process involved in assembly of the presynaptic membrane in which neurexins are localized to distinct domains in the cell membrane. Neurexins are synaptic cell surface proteins which act as cell recognition molecules at nerve terminals.


positive regulation of neuromuscular synaptic transmission

Any process that activates or increases the frequency, rate or extent of neuromuscular synaptic transmission.


OSR2_HUMAN Protein odd-skipped-related 2 (sprot)

A protein odd-skipped-related 2 that is encoded in the genome of human.


FA43A_HUMAN Protein FAM43A (sprot)

A protein FAM43A that is encoded in the genome of human.


LTBP4_HUMAN Latent-transforming growth factor beta-binding protein 4 (sprot)

A latent-transforming growth factor beta-binding protein 4 that is encoded in the genome of human.


TM256_HUMAN Transmembrane protein 256 (sprot)

A UPF0382 inner membrane protein YgdD that is encoded in the genome of human.


S66A2_HUMAN Solute carrier family 66 member 2 (sprot)

A solute carrier family 66 member 2 that is encoded in the genome of human.


PIAS4_HUMAN E3 SUMO-protein ligase PIAS4 (sprot)

An E3 SUMO-protein ligase PIAS4 that is encoded in the genome of human.


limb epidermis development

The process whose specific outcome is the progression of the epidermis of the limb over time, from its formation to the mature structure. The limb epidermis is the outer epithelial layer of the limb, it is a complex stratified squamous epithelium.


EXAS1_HUMAN Uncharacterized protein EXOC3-AS1 (sprot)

A protein that is a translation product of the EXOC3-AS1 gene in human.


RUSC2_HUMAN AP-4 complex accessory subunit RUSC2 (sprot)

An AP-4 complex accessory subunit RUSC2 that is encoded in the genome of human.


CENPS_HUMAN Centromere protein S (sprot)

A centromere protein S that is encoded in the genome of human.


SVBP_HUMAN Small vasohibin-binding protein (sprot)

A small vasohibin-binding protein that is encoded in the genome of human.


regulation of metallopeptidase activity

Any process that modulates the frequency, rate or extent of metallopeptidase activity.


AGGF1_HUMAN Angiogenic factor with G patch and FHA domains 1 (sprot)

An angiogenic factor with G patch and FHA domains 1 that is encoded in the genome of human.


MUC20_HUMAN Mucin-20 (sprot)

A mucin-20 that is encoded in the genome of human.


NXPE1_HUMAN NXPE family member 1 (sprot)

An NXPE family member 1 that is encoded in the genome of human.


CJ111_HUMAN Putative uncharacterized protein RPP38-DT (sprot)


PGBD3_HUMAN PiggyBac transposable element-derived protein 3 (sprot)

A piggyBac transposable element-derived protein 3 that is encoded in the genome of human.


GPD1L_HUMAN Glycerol-3-phosphate dehydrogenase 1-like protein (sprot)

A glycerol-3-phosphate dehydrogenase 1-like protein that is encoded in the genome of human.


ELMD1_HUMAN ELMO domain-containing protein 1 (sprot)

An ELMO domain-containing protein 1 that is encoded in the genome of human.


MT1M_HUMAN Metallothionein-1M (sprot)

A metallothionein-1M that is encoded in the genome of human.


MIER2_HUMAN Mesoderm induction early response protein 2 (sprot)

A mesoderm induction early response protein 2 that is encoded in the genome of human.


OR2LD_HUMAN Olfactory receptor 2L13 (sprot)

An olfactory receptor 2L13 that is encoded in the genome of human.


CBARP_HUMAN Voltage-dependent calcium channel beta subunit-associated regulatory protein (sprot)

A voltage-dependent calcium channel beta subunit-associated regulatory protein that is encoded in the genome of human.