negative regulation of stomach fundus smooth muscle contraction

Any process that decreases the frequency, rate or extent of any stomach fundus smooth muscle contraction.


negative regulation of eosinophil differentiation

biolink:BiologicalProcess biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:Occurrent biolink:OntologyClass biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

Any process that stops, prevents, or reduces the frequency, rate or extent of eosinophil differentiation.


cAMP receptor activity

biolink:MolecularActivity biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:Occurrent biolink:OntologyClass biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

Combining with cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


locus ceruleus formation

The process that gives rise to the locus ceruleus. This process pertains to the initial formation of a structure from unspecified parts. In mice, the locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic.


positive regulation of immature T cell proliferation

Any process that activates or increases the frequency, rate or extent of immature T cell proliferation.


dIMP salvage

Any process which produces a dIMP from derivatives of it, without de novo synthesis.


P-type cadmium transporter activity

Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Cd2+(in) = ADP + phosphate + Cd2+(out).


Spemann organizer formation at the embryonic shield

Formation of the specialized region of the embryonic shield of the embryo that acts as the main signaling center establishing the teleost body plan.


Se-methyltransferase activity

Catalysis of the transfer of a methyl group to the selenium atom of an acceptor molecule.


regulation of female pigmentation

Any process that modulates the frequency, rate or extent of establishment of a pattern of pigment in females.


hypoglossal nerve structural organization

The process that contributes to the act of creating the structural organization of the hypoglossal nerve. This process pertains to the physical shaping of a rudimentary structure. This motor nerve innervates all the intrinsic and all but one of the extrinsic muscles of the tongue.


sigma factor antagonist activity

The function of binding to a sigma factor and stopping, preventing or reducing the rate of its transcriptional activity.


histone H4K deacetylase activity

Catalysis of the reaction: histone H4 N6-acetyl-L-lysine + H2O = histone H4 L-lysine + acetate. This reaction represents the removal of an acetyl group from a histone H4.


negative regulation of leukocyte differentiation

Any process that stops, prevents or reduces the frequency, rate or extent of leukocyte differentiation.


regulation of prostaglandin-E synthase activity

Any process that modulates the frequency, rate or extent of prostaglandin-E synthase activity.


regulation of lymphocyte proliferation

Any process that modulates the frequency, rate or extent of lymphocyte proliferation.


negative regulation by symbiont of host synaptic transmission

Any process in which a symbiont organism decreases the frequency, rate or extent of synaptic transmission, communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse, in its host organism.


griseofulvin biosynthetic process

The chemical reactions and pathways resulting in the formation of griseofulvin, an important antifungal drug that has been in use for a long time for treating dermatophyte infections.


umbilical cord development

The process whose specific outcome is the development of the umbilical cord, from its formation to the mature structure. The umbilical cord is an organ or embryonic origin consisting of the 2 umbilical arteries and the one umbilical vein. The umbilical cord connects the cardiovascular system of the fetus to the mother via the placenta.


Catalysis of the reaction: acetyl-CoA + a monoterpenol = CoA + a monoterpenol acetate ester.


anatomical structure homeostasis

A homeostatic process involved in the maintenance of an internal steady state within a defined anatomical structure of an organism, including control of cellular proliferation and death and control of metabolic function. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.


detoxification of iron ion

Any process that reduces or removes the toxicity of iron ion. These include transport of iron away from sensitive areas and to compartments or complexes whose purpose is sequestration of iron ion.


selenotransferase activity

Catalysis of the transfer of a selenium-containing group from one compound (donor) to another (acceptor).


isoprenoid biosynthetic process via mevalonate

The chemical reactions and pathways resulting in the formation of isoprenoid via mevalonate.


isopentadecanoic acid binding

Binding to isopentadecanoic acid.


cellular response to endogenous stimulus

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus arising within the organism.


jasmonic acid and ethylene-dependent systemic resistance, ethylene mediated signaling pathway

biolink:Pathway biolink:BiologicalProcess biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:OntologyClass biolink:Occurrent biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

The series of molecular signals mediated by ethylene (ethene) involved in jasmonic acid/ethylene dependent systemic resistance.


reuteran biosynthetic process

The chemical reactions and pathways resulting in the formation of reuteran, a soluble glucan polymer with mainly alpha-(1->4) glycosidic linkages and significant amounts of alpha-(1->6) and alpha-(1->4,6) glucosidic linkages.


cellular response to immobilization stress

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of being rendered immobile.


negative regulation of L-glutamine import across plasma membrane

Any process that stops, prevents or reduces the frequency, rate or extent of L-glutamine import into a cell.


cyanide biosynthetic process

The chemical reactions and pathways resulting in the formation of cyanide, NC-, the anion of hydrocyanic acid. Cyanide is a potent inhibitor of respiration.


dormancy process

A developmental process in which dormancy (sometimes called a dormant state) is induced, maintained or broken. Dormancy is a suspension of most physiological activity and growth that can be reactivated.


regulation of erythrocyte aggregation

Any process that modulates the frequency, rate, or extent of erythrocyte aggregation.


peripheral B cell deletion

The deletion of B cells by apoptotic process occurring as part of peripheral tolerance induction and B cell selection.


hydroxymalonate dehydrogenase activity

Catalysis of the reaction: hydroxymalonate + NAD+ = H+ + NADH + oxomalonate.


2,3-dihydroxy DDT 1,2-dioxygenase activity

Catalysis of the reaction: 2,3-dihydroxy DDT + O2 = 6-oxo-2-hydroxy-7-(4-chlorophenyl)-3,8,8,8-tetrachloroocta-2E,4E-dienoate.


Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + quercetin 3-sulfate = adenosine 3',5'-diphosphate + H+ + quercetin 3,4'-disulfate.


Catalysis of the reaction: 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H2O + imidazol-4-ylacetate = 1-(5-phosphoribosyl)imidazol-4-ylacetate + ADP + diphosphate + 2 H+ + phosphate.


macrophage antigen processing and presentation

The process in which a macrophage expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex.


Catalysis of the reaction: alpha-D-glucose 1-phosphate + CTP = CDP-D-glucose + diphosphate.


negative regulation of branchiomeric skeletal muscle development

Any process that stops, prevents, or reduces the frequency, rate or extent of branchiomeric skeletal muscle development. Branchiomeric skeletal muscle development is the process whose specific outcome is the progression of the branchiomeric skeletal muscle over time, from its formation to the mature structure.


germarium-derived cystoblast division

The four rounds of incomplete mitosis undergone by a cystoblast to form a 16-cell cyst of interconnected cells within a germarium. Within the cyst, one cell differentiates into an oocyte while the rest become nurse cells. An example of this process is found in Drosophila melanogaster.


Catalysis of the reaction: 5-dehydro-4-deoxy-D-glucuronate = 3-deoxy-D-glycero-2,5-hexodiulosonate.


cross bridge cycling involved in regulation of the velocity of shortening in skeletal muscle contraction

A process in which cross bridges are broken and reformed during filament sliding as part of the regulation of the velocity of shortening in skeletal muscle contraction.


lsiRNA processing

A process leading to the generation of a functional long small interfering RNA (lsiRNA). lsiRNAs are class of siRNAs 30 to 40 nt in length. lsiRNAs are induced by pathogen infection or under specific growth conditions.


histone H3K36 acetyltransferase activity

Catalysis of the reaction: acetyl-CoA + histone H3 L-lysine (position 36) = CoA + histone H3 N6-acetyl-L-lysine (position 36).


Catalysis of the reaction: N-acetyl-D-mannosamine-6-phosphate = N-acetyl-D-glucosamine-6-phosphate.


glyphosate dehydrogenase activity

Catalysis of the reaction: glyphosate + OH- = glyoxylate + aminomethylphosphonic acid + H+ + 2 e-.


Catalysis of the reaction: (25S)-5beta-spirostan-3beta-ol + UDP-D-glucose = (25S)-5beta-spirostan-3beta-yl beta-D-glucoside + H+ + UDP.


aggregation of unicellular organisms

The clustering together of unicellular organisms in suspension form aggregates.


1,2-dichloroethene reductive dehalogenase activity

Catalysis of the reaction: 1,2-dichloroethene + 2 H+ + 2 e- = HCl + vinyl chloride.


regulation of amino acid transport

Any process that modulates the frequency, rate or extent of the directed movement of amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


11-deoxycortisol binding

Binding to 11-deoxycortisol.


regulation of vascular associated smooth muscle cell differentiation

Any process that modulates the frequency, rate or extent of vascular smooth muscle cell differentiation.


phytoene catabolic process

The chemical reactions and pathways resulting in the breakdown of phytoene.


podocyte cell fate commitment

The process in which the developmental fate of a cell becomes restricted such that it will develop into a glomerular visceral epithelial cell. A glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells.


smooth muscle cell differentiation involved in prostate glandular acinus development

The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell of the prostate glandular acinus.


establishment or maintenance of polarity of larval imaginal disc epithelium

Any cellular process that results in the specification, formation or maintenance of a polarized larval imaginal disc epithelium.


epicardium-derived cardiac endothelial cell differentiation

The process in which an epicardial cell acquires the specialized structural and/or functional features of a cardiac endothelial cell.


neopullulanase activity

Catalysis of the hydrolysis of pullulan to panose (6-alpha-D-glucosylmaltose).


coumarin biosynthetic process

The chemical reactions and pathways resulting in the formation of coumarins, a class of compounds derived from the phenylacrylic skeleton of cinnamic acids.


molting cycle process

A multicellular organismal process involved in the periodic casting off and regeneration of an outer covering of cuticle, feathers, hair, horns, skin.


valine decarboxylase activity

Catalysis of the reaction: L-valine + H+ = 2-methylpropanamine + CO2.


modulation by symbiont of host cell motility

Modulation of host cell motility by a symbiont of that host.


cell proliferation in hindbrain ventricular zone

The multiplication or reproduction of cells, resulting in the expansion of a cell population in the hindbrain region that is adjacent to the ventricular cavity.


regulation of male germ-line stem cell asymmetric division

Any process that modulates the frequency, rate or extent of male germ-line stem cell asymmetric division.


p-cymene metabolic process

The chemical reactions and pathways involving p-cymene, 1-methyl-4-isopropylbenzene, one of the alkyl-substituted aromatic hydrocarbons found in volatile oils from over 100 plants.


polyol biosynthetic process

The chemical reactions and pathways resulting in the formation of a polyol, any alcohol containing three or more hydroxyl groups attached to saturated carbon atoms.


chemoattraction involved in embryonic olfactory bulb interneuron precursor migration

The creation and reception of signals that result in the migration of interneuron precursors up a concentration gradient towards the olfactory bulb.


aldehyde decarbonylase activity

Catalysis of the reaction: a C(n) aldehyde = C(n-1) alkane + CO.


pyrimidine nucleobase salvage

Any process that generates pyrimidine nucleobases, 1,3-diazine organic nitrogenous bases, from derivatives of them without de novo synthesis.


delta 3-trans-hexadecenoic acid phosphatidylglycerol desaturase activity

Catalysis of the reaction: 1-18:3-3-16:0-phosphatidylglycerol = 1-18:3-3-trans-16:1-phosphatidylglycerol + 2 H+. This reaction is the formation of a trans double bond between carbon 3 and carbon 4 (counting from the carboxyl end) of palmitic acid, which is specifically esterified to the sn-2 glyceryl carbon of phosphatidylglycerol.


recombination within rDNA repeats

Genetic recombination within the DNA of the genes coding for ribosomal RNA.


Catalysis of the reaction: (4-hydroxyphenyl)acetate + H+ = 4-cresol + CO2.


(deoxy)nucleoside phosphate kinase activity, GTP as phosphate donor

Catalysis of the reaction: a 2'-deoxyribonucleoside 5'-phosphate + GTP = a 2'-deoxyribonucleoside 5'-diphosphate + GDP.


N-glycolylneuraminic acid (Neu5Gc) cytidylyltransferase activity

Catalysis of the reaction: CTP + Neu5Gc = diphosphate + CMP-Neu5Gc.


very-long-chain fatty acyl-CoA oxidase activity

Catalysis of the reaction: very-long-chain fatty acyl-CoA (C22 - C24) + O2 = trans-2,3-dehydroacyl-CoA + hydrogen peroxide.


ribonuclease V activity

Catalysis of the hydrolysis of poly(A), forming oligoribonucleotides and ultimately 3'-AMP.


detection of low humidity

The series of events in which low humidity is detected and converted into a molecular signal.


regulation of response to cytokinesis checkpoint signaling

Any process that modulates the frequency, rate or extent of response to cytokinesis checkpoint signaling.


Gi/o-coupled serotonin receptor activity

Combining with serotonin and transmitting the signal across the membrane by activation of the Gi/o subunit of an associated cytoplasmic heterotrimeric G protein complex. The Gi/o subunit subsequently inhibits adenylate cyclase and results in a decrease in cyclic AMP (cAMP) levels.


detection of temperature stimulus involved in sensory perception

The series of events in which a temperature stimulus is received and converted into a molecular signal as part of sensory perception.


sinapoyl spermidine:sinapoyl CoA N-acyltransferase activity

Catalysis of the transfer of a sinapoyl group to a nitrogen atom on a sinapoyl spermidine molecule resulting in the formation of a disinapoyl spermidine derivative.


positive regulation of renal phosphate excretion

Any process that activates or increases the frequency, rate or extent of renal phosphate excretion.


positive regulation of sporocarp development involved in sexual reproduction

Any process that activates or increases the frequency, rate or extent of sporocarp development involved in sexual reproduction.


protein-containing complex destabilizing activity

A molecular function that involves direct binding to one of the subunits of a protein-containing complex and promoting the dissociation of one or many subunits. This often happens by changing the conformation of the protein being bound, which decreases its affinity for the rest of the complex.


alpha-patchoulene synthase activityy

Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = diphosphoric acid + alpha-patchoulene.


cellularization

The separation of a multi-nucleate cell or syncytium into individual cells. An example of this is found in Drosophila melanogaster embryo development.


UDP-glucuronate 4-epimerase activity

Catalysis of the reaction: UDP-alpha-D-glucuronate = UDP-alpha-D-galacturonate.


Catalysis of the reaction: eugenol + S-adenosyl-L-methionine = H+ + O-methyleugenol + S-adenosyl-L-homocysteine.


response to mercaptoethanol

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mercaptoethanol stimulus.


cingulate gyrus development

The progression of the cingulate gyrus over time from its initial formation until its mature state. The cingulate gyrus is a ridge in the cerebral cortex located dorsal to the corpus callosum.


modulation of voltage-gated potassium channel activity in another organism

Any process in which an organism effects a change in the frequency, rate or extent of the activity of a voltage-gated potassium channel in another organism.


Catalysis of the reaction: 10-desacetyltaxuyunnanin C + acetyl-CoA = CoA + taxuyunnanin C.


anterior lateral line ganglion development

The process whose specific outcome is the progression of the anterior lateral line ganglion over time, from its formation to the mature structure. The anterior lateral line ganglion develops from cranial ectodermal placodes situated between the eye and ear.


regulation of sulfur utilization

Any process that modulates the frequency, rate or extent of sulfur utilization.


RNA replication

The cellular metabolic process in which a cell duplicates one or more molecules of RNA.


regulation of flower development

Any process that modulates the frequency, rate or extent of flower development.


processes downstream of sex determination signal

The sex determination processes that take place after the initial transmission of the sexual phenotype to specific information pathways.


positive regulation of postsynaptic cytosolic calcium concentration

Any process that increases the concentration of calcium ions in the postsynaptic cytosol.


trihydroxyferuloyl spermidine O-methyltransferase activity

Catalysis of the reaction: trihydroxyferuloyl spermidine + S-adenosyl-L-methionine = dihydroxyferuloyl-sinapoyl spermidine + S-adenosyl-L-homocysteine + H+.


flight

Self-propelled movement of an organism from one location to another through the air, usually by means of active wing movement.


Catalysis of the reaction: (3Z)-phycocyanobilin + oxidized ferredoxin = biliverdin IXa + reduced ferredoxin.


ergosterol metabolic process

The chemical reactions and pathways involving ergosterol, (22E)-ergosta-5,7,22-trien-3-beta-ol, a sterol found in ergot, yeast and moulds. It is the most important of the D provitamins and is converted to vitamin D2 on irradiation with UV light.


biofilm matrix organization

A process that results in the assembly, arrangement of constituent parts, or disassembly of a biofilm matrix.


L-arabinose 1-dehydrogenase (NADP+) activity

Catalysis of the reaction: L-arabinose + NADP+ = L-arabinono-1,4-lactone + NADPH + H+.


modulation by virus of host autophagy

Any process in which a virus effect a change in the frequency, rate or extent of autophagy in the host.


Catalysis of the reaction: 3',4',5-trihydroxy-3-methoxyflavon-7-olate + S-adenosyl-L-methionine <=> 3,3'-dimethylquercetin + S-adenosyl-L-homocysteine.


menthone dehydrogenase activity

Catalysis of the reaction: (-)-(2S,5R)-menthone + NAD+ = (5R)-menth-2-enone + NADH + H+.


negative regulation of macromolecule metabolic process

Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.


sulfite dehydrogenase activity

Catalysis of the reaction: sulfite + 2 ferricytochrome c + H2O = sulfate + 2 ferrocytochrome c.


positive regulation of cyanophore differentiation

Any process that activates or increases the frequency, rate or extent of cyanophore differentiation.


regulation of heart induction

Any process that modulates the rate, frequency, or extent of heart induction. Heart induction is the close range interaction between mesoderm and endoderm or ectoderm that causes cells to change their fates and specify the development of the heart.


negative regulation of cardiac endothelial to mesenchymal transition

Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac endothelial to mesenchymal transition.


positive regulation of inflammasome-mediated signaling pathway

Any process that activates or increases the frequency, rate or extent of an inflammasome-mediated signaling pathway.


spike train

A series of sequential, propagated action potentials occurring in a single cell.


positive regulation of activation-induced cell death of T cells

Any process that activates or increases the frequency, rate or extent of activation-induced cell death of T cells.


sorbitol transmembrane transporter activity

Enables the transfer of sorbitol from one side of a membrane to the other. Sorbitol, also known as glucitol, is the hexitol derived by the reduction of the aldehyde group of glucose.


Catalysis of the reaction: ethyl (S)-3-hydroxyhexanoate + NADP+ = ethyl 3-oxohexanoate + H+ + NADPH.


adonirubin 3-hydroxylase activity

Catalysis of the reaction: adonirubin + a reduced electron acceptor + oxygen = 3S,3'S-astaxanthin + an oxidized electron acceptor + H2O.


Catalysis of the reaction: (2E,4E)-6-(2-aminophenyl)-2-hydroxy-6-oxohexa-2,4-dienoate + H2O <=> H+ + anthranilate + (2E)-2-hydroxypenta-2,4-dienoate.


O-glycan processing, core 6

The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form the core 6 O-glycan structure, GlcNAc-beta-(1->6)-GalNAc.


negative regulation of anthocyanin biosynthetic process

Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of anthocyanins.


neural keel formation

The formation of a thickened region of the neurectoderm that is roughly triangular in cross section. The neural keel develops from the neural plate and develops into the neural rod. Neural keel formation occurs during primary neurulation in teleosts.


cellular response to inositol starvation

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of inositol.


androecium development

The process whose specific outcome is the progression of the androecium over time, from its formation to the mature structure.


Catalysis of the reaction: acetyl-CoA + cysteamine = S-acetylcysteamine + CoA.


2-deoxyglucosidase activity

Catalysis of the reaction: H2O + a 2-deoxy-alpha-D-glucoside = 2-deoxy-D-glucose + an alcohol.


peptidyl-cysteine sulfation

The sulfation of peptidyl-cysteine to form S-sulfo-L-cysteine.


amino acid catabolic process via Ehrlich pathway

The chemical reactions and pathways involving the catabolism of amino acids to produce alcohols or carboxylic acids containing one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of alcohols, often collectively referred to as fusel alcohols. Depending on the redox state of the cells, carboxylic acid derivatives, sometimes referred to as fusel acids, may be produced instead of alcohols.


6-hydroxycineole metabolic process

The chemical reactions and pathways involving 6-hydroxycineole (6-hydroxy-1,8-epoxy-p-menthane), a hydrocarbon with the formula C10H18O2.


negative regulation of aggregation involved in sorocarp development

Any process that decreases the frequency, rate or extent of aggregation involved in sorocarp development. Aggregation involved in sorocarp development is the process whose specific outcome is the progression of the aggregate over time, from its formation to the point when a slug is formed. Aggregate development begins in response to starvation and continues by the chemoattractant-mediated movement of cells toward each other. The aggregate is a multicellular structure that gives rise to the slug.


imaginal disc-derived leg morphogenesis

The process in which the anatomical structures of a leg derived from an imaginal disc are generated and organized. A leg is a limb on which an animal walks and stands. An example of this is found in Drosophila melanogaster.


ncRNA metabolic process

The chemical reactions and pathways involving non-coding RNA transcripts (ncRNAs).


positive regulation of acylglycerol transport

Any process that activates or increases the frequency, rate or extent of acylglycerol transport.


response to tetrahydrofolate

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tetrahydrofolate stimulus.


myo-inositol hexakisphosphate metabolic process

The chemical reactions and pathways involving phytic acid, myo-inositol hexakisphosphate, a regulator of intracellular signaling, a highly abundant animal anti-nutrient and a phosphate and mineral storage compound in plant seeds.


cellulose synthase (GDP-forming) activity

Catalysis of the reaction: GDP-glucose + ((1,4)-beta-D-glucosyl)(n) = GDP + ((1,4)-beta-D-glucosyl)(n+1).


pollen exine formation

The formation of the pollen exine. The reticulate pollen wall pattern consists of two layers, exine and intine.


methanol biosynthetic process

The chemical reactions and pathways resulting in the formation of methanol, CH3-OH, a colorless, flammable, mobile, poisonous liquid, widely used as a solvent.


endosulfan diol hydrolyase (cyclizing) activity

Catalysis of the reaction: endosulfan diol = endosulfan ether + H2O.


regulation of asexual reproduction

Any process that modulates the frequency, rate or extent of asexual reproduction.


positive regulation of asymmetric cell division

Any process that activates or increases the frequency, rate or extent of asymmetric cell division.


pseudouridylate synthase activity

Catalysis of the reaction: D-ribose 5-phosphate + uracil = H2O + pseudouridine 5'-phosphate.


atrial septum intermedium morphogenesis

The process in which anatomical structure of an atrial septum intermedium is generated and organized.


Catalysis of the reaction: ent-copalyl diphosphate = ent-pimara-8(14),15-diene + diphosphate.


regulation of aldosterone secretion

Any process that modulates the frequency, rate or extent of aldosterone secretion.


phosphate ion transmembrane transporter activity

Enables the transfer of phosphate (PO4 3-) ions from one side of a membrane to the other.


follicle cell of egg chamber development

The process that occurs during oogenesis involving the ovarian follicle cells, somatic cells which surround the germ cells of an ovary. An example of this is found in Drosophila melanogaster.


ABC-type indole transporter activity

Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + indole(in) = ADP + phosphate + indole(out).


allulose 6-phosphate 3-epimerase activity

Catalysis of the reaction: D-allulose 6-phosphate = D-fructose 6-phosphate.


The chemical reactions and pathways resulting in the breakdown of sphinganine-1-phosphate, the phosphorylated derivative of D-erythro-2-amino-1,3-octadecanediol.


inhibitory killer cell immunoglobulin-like receptor signaling pathway

The series of molecular signals initiated by an extracellular ligand binding to a inhibitory killer cell immunoglobulin-like receptor capable of inhibiting an immune effector process contributing to an immune response.


interleukin-26 receptor activity

Combining with interleukin-26 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


positive regulation of leaflet formation by auxin mediated signaling pathway

Any process that increases the frequency, rate or extent of leaflet formation as a result of the series of molecular signals generated in response to detection of auxin.


1-naphthoic acid dioxygenase activity

Catalysis of the reaction: 1-naphthoic acid + NADH + O2 + H+ = cis-1,2-dihydroxy-1,2-dihydro-8-carboxynaphthalene + NAD+.


chanoclavine-I metabolic process

The chemical reactions and pathways involving chanoclavine-I.


socially cooperative development

The process whose specific outcome is the progression of a non-reproductive fruiting body over time, from its formation to the mature structure. A non-reproductive fruiting body is a colonial multicellular structure consisting of co-operating unicellular organisms, some of which are spores. An example of such a process is found in Dictyostelium discoideum and Myxococcus xanthus colonies.


cardiac muscle atrophy

A process, occurring in the heart, in which a decrease in cell mass and then in heart size occurs due to shrinking of the individual cells. The shrinkage is caused by protein degradation.


germ-line cyst encapsulation

Formation of a single follicular epithelium around the germ-line derived cells of a cyst.


cardioblast migration

The orderly movement of a cardiac progenitor cell to form the heart field. Cardiac progenitor cells are non-terminally differentiated, mesoderm-derived cells that are committed to differentiate into cells of the heart. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.


biphenyl 2,3-dioxygenase activity

Catalysis of the reaction: biphenyl + NADH + H+ + O2 = (2R,3S)-3-phenylcyclohexa-3,5-diene-1,2-diol + NAD+. This reaction requires Fe2+.


Catalysis of the reaction: 4-isopropylaniline + H2O = 4'-(2-hydroxyisopropyl)phenylaniline + 2 H+ + 2 e-.


arginine catabolic process to spermine

The chemical reactions and pathways resulting in the breakdown of arginine into other compounds, including spermine.


L-xylulose reductase (NAD+) activity

Catalysis of the reaction: xylitol + NAD+ = L-xylulose + NADH + H+.


succinate-semialdehyde dehydrogenase [NAD(P)+] activity

Catalysis of the reaction: succinate semialdehyde + NAD(P)+ + H2O = succinate + NAD(P)H + H+.


sulfur utilization

A series of processes that forms an integrated mechanism by which a cell or an organism detects the depletion of primary sulfur sources and then activates genes to scavenge the last traces of the primary sulfur source and to transport and metabolize alternate sulfur sources. The utilization process begins when the cell or organism detects sulfur levels, includes the activation of genes whose products detect, transport or metabolize sulfur-containing compounds, and ends when the sulfur is incorporated into the cell or organism's metabolism.


beak morphogenesis

The process in which the anatomical structures of the beak are generated and organized. The avian beak is an external anatomical structure, in the head region, that is adapted for feeding self and young, catching prey, probing, etc. It encompasses, but is not restricted to, the maxilla, mandible, maxillary rhamphotheca, mandibular rhamphotheca, nostril, nasal fossa, nasal bones, egg tooth and rictus.


positive regulation of invasive growth in response to glucose limitation

Any process that activates or increases the frequency, rate or extent of invasive growth in response to glucose limitation.


superior olivary nucleus morphogenesis

The process in which the anatomical structure of the superior olivary nucleus is generated and organized. In mice, the superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound.


cell proliferation in external granule layer

The multiplication or reproduction of neuroblasts resulting in the expansion of a cell population in the external granule layer of the hindbrain. The external granule layer is the layer that originates from the rostral half of the rhombic lip in the first rhombomere.


acryloyl-CoA reductase (NADP+) activity

Catalysis of the reaction: acryloyl-CoA + NADPH + H+ = propionyl-CoA + NADP+.


detection of pH by carotid body chemoreceptor signaling

The process in which information about the levels of hydrogen ions are received and are converted to a molecular signal by chemoreceptors in a carotid body.


benzoyl-CoA 3-monooxygenase activity

Catalysis of the reaction: benzoyl-CoA + H+ + NADPH + O2 = 3-hydroxybenzoyl-CoA + H2O + NADP+.


pentalenene synthase activity

Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = diphosphate + pentalenene.


regulation of B-1 B cell differentiation

Any process that modulates the frequency, rate, or extent of B-1 B cell differentiation. B-1 B cells are a distinct subset of B cells characterized as being CD5 positive, found predominantly in the peritoneum, pleural cavities, and spleen, and enriched for self-reactivity.


regulation of response to cycloalkane

Any process that modulates the frequency, rate or extent of response to cycloalkane.


viral mRNA export from host cell nucleus

The directed movement of intronless viral mRNA from the host nucleus to the cytoplasm for translation.


CYP79F1 dihomomethionine monooxygenase activity

Catalysis of the reaction: dihomomethionine + 2 O2 + 2 NADPH + 2 H+ <=> 5-methylthiopentanaldoxime + 3 H2O + carbon dioxide + 2 NADP.


acyl-phosphate glycerol-3-phosphate acyltransferase activity

Catalysis of the reaction: acyl phosphate + sn-glycerol 3-phosphate = 1-acyl-sn-glycerol 3-phosphate + orthophosphate.


conus arteriosus development

The progression of the conus arteriosus over time, from its formation to the mature structure. The conus arteriosus is a valved chamber with thick muscular walls stemming from the ventricle and connecting to the pulmonary trunk.


2-deoxystreptamine biosynthetic process

The chemical reactions and pathways resulting in the formation of 2-deoxystreptamine.


positive regulation of the force of heart contraction by circulating epinephrine-norepinephrine

Any process that increases the force with which the cardiac muscles of the heart pump blood through the circulatory system as a result of the presence of epinephrine or norepinephrine in the bloodstream.


regulation of epithelial tube formation

Any process that modulates the frequency, rate or extent of epithelial tube formation.


AAU codon-amino acid adaptor activity

A triplet codon-amino acid adaptor activity that recognizes an AAU codon.


allose 6-phosphate isomerase activity

Catalysis of the reaction: D-allose-6-phosphate = D-allulose-6-phosphate.


cellular response to dextromethorphan

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dextromethorphan stimulus.


(S)-2-haloacid dehalogenase activity

Catalysis of the reaction: (S)-2-haloacid + H2O = (R)-2-hydroxyacid + halide.


Catalysis of the reaction: alpha,alpha-trehalose + phosphate = D-glucose + beta-D-glucose 1-phosphate.


Catalysis of the reaction: N-acetylneuraminyl-2,3-alpha-D-galactosyl-1,4-beta-D-glucosylceramide + UDP-N-acetylgalactosamine = N-acetyl-beta-D-galactosaminyl-1,4-(N-acetyl-alpha-neuraminyl-2,3)-beta-D-galactosyl-1,4-beta-D-glucosylceramide + UDP.


Catalysis of the reaction: 2alpha-hydroxytaxusin + NADPH + O2 + H+ <=> 2alpha, 7beta-dihydroxytaxusin + NADP + H2O.


protoporphyrinogen IX biosynthetic process from glutamate

The chemical reactions and pathways resulting in the formation of protoporphyrinogen IX from other compounds, including glutamate.


nodulation

The formation of nitrogen-fixing root nodules on plant roots.


Catalysis of the reaction: indole-3-acetate + L-tryptophan + ATP(4-) <=> H+ + indole-3-acetyl-tryptophan + AMP(2-) + diphosphoric acid.


virion maturation

Maturation of a virion after separation from the host cell. Not all viruses mature after separation. In those that do, maturation typically involves rearangement and/or cleavage of viral proteins, resulting in the virion becoming competent for reinfection.


positive regulation of conidium formation

Any process that activates, maintains or increases the frequency, rate or extent of conidium formation, a process of producing non-motile spores, called conidia, via mitotic asexual reproduction in higher fungi. Conidia are haploid cells genetically identical to their haploid parent. They are produced by conversion of hyphal elements, or are borne on sporogenous cells on or within specialized structures termed conidiophores, and participate in dispersal of the fungus.


response to viscosity

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a viscosity stimulus.


peptidyl-glutamic acid methylation

The addition of a methyl group to a glutamic acid residue in a protein.


benzoate transmembrane transporter activity

Enables the directed movement of benzoate, the anion of benzoic acid (benzenecarboxylic acid) from one side of a membrane to the other.


2-dehydropantoate aldolase activity

Catalysis of the reaction: 2-dehydropantoate = 3-methyl-2-oxobutanoate + formaldehyde.


Catalysis of the reaction: 6-methylthiohexyldesulfoglucosinolate + 3'-phosphonato-5'-adenylyl sulfate <=> adenosine 3',5'-bismonophosphate + H+ + 6-methylthiohexylglucosinolate.


regulation of antigen processing and presentation of peptide antigen via MHC class II

Any process that modulates the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class II.


methylthiol:coenzyme M methyltransferase activity

Catalysis of the overall reaction: methyl-Co(III) methylated-thiol-specific corrinoid protein + coenzyme M = Co(I) methylated--thiol-specific corrinoid protein + methyl-CoM.


geranylgeranyl diphosphate reductase activity

Catalysis of the reaction: (E)-3,7,11,15-tetramethylhexadec-2-en-1-yl diphosphate + 3 NADP <=> 2-trans,6-trans,10-trans-geranylgeranyl diphosphate + 3 NADPH + 3 H+.


regulation of brown fat cell proliferation

Any process that modulates the frequency, rate or extent of brown fat cell proliferation.


arginine racemase activity

Catalysis of the reaction: L-arginine = D-arginine.


olefin metabolic process

The chemical reactions and pathways involving olefin.


apocarotenoid biosynthetic process

The chemical reactions and pathways resulting in the formation of apocarotenoids by the oxidative cleavage of carotenoids. Many apocarotenoids are biologically important e.g. retinal and abscisic acid.


positive regulation of eye photoreceptor cell development

Any process that activates or increases the frequency, rate or extent of eye photoreceptor development.


induction of conjugation upon nutrient starvation

The process in which a cell initiates conjugation with cellular fusion upon starvation for one or more nutrients.


dimethylsilanediol metabolic process

The chemical reactions and pathways involving dimethylsilanediol, the smallest member of the dialkylsilanediols. Dimethylsilanediol is the monomer of polydimethylsiloxane, a compound which can be found in a wide range of industrial and consumer products.


rolling circle DNA replication

A DNA-dependent DNA replication process in which a single-stranded DNA molecule is synthesized from a circular duplex template. Replication typically does not cease when one circumference has been replicated, but continues around the circumference several more times, producing a long single strand comprising multimers of the replicon.


regulation of lateral motor column neuron migration

Any process that modulates the frequency, rate or extent of lateral motor column neuron migration.


Catalysis of the reaction: 4-amino-2-methyl-5-diphosphomethylpyrimidine + 4-methyl-5-(2-phosphoethyl)-thiazole + H+ = diphosphate + thiamine phosphate.


tridecane metabolic process

The chemical reactions and pathways involving tridecane.


negative regulation of somitomeric trunk muscle development

Any process that stops, prevents, or reduces the frequency, rate or extent of somitomeric trunk muscle development. The somitomeric trunk muscle is derived from somitomeric mesoderm. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle.


(+)-camphor metabolic process

The chemical reactions and pathways involving (+)-camphor, a bicyclic monoterpene ketone which is one of the major components in the leaves of common sage. Camphor exists in two enantiomers, but the (+)-isomer is more widely distributed.


ribonuclease T1 activity

Catalysis of the endonucleolytic cleavage to nucleoside 3'-phosphates and 3'-phosphooligonucleotides ending in Gp with 2',3'-cyclic phosphate intermediates.


somatic hypermutation of immunoglobulin genes involved in immune response

Mutations occurring somatically that result in amino acid changes in the rearranged V regions of immunoglobulins following the induction of and contributing to an immune response.


collagen and cuticulin-based cuticle development

Synthesis and deposition of a collagen and cuticulin-based noncellular, hardened, or membranous secretion from an epithelial sheet. An example of this process is found in Caenorhabditis elegans.


ferredoxin-nitrate reductase activity

Catalysis of the reaction: nitrite + H2O + 2 oxidized ferredoxin = nitrate + 2 reduced ferredoxin.


pons morphogenesis

The process in which the anatomical structure of the pons is generated and organized. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum.


interphase microtubule organizing center assembly

The aggregation, arrangement and bonding together of a set of components, including gamma-tubulin and other proteins, to form an interphase microtubule organizing center.


anatomical structure arrangement

The process that gives rise to the configuration of the constituent parts of an anatomical structure. This process pertains to the physical shaping of a rudimentary structure. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.


iron incorporation into iron-sulfur cluster via tris-L-cysteinyl L-cysteine persulfido bis-L-glutamato L-histidino nickel triiron disulfide trioxide

The incorporation of iron into a 3Fe-2S cluster via tris-L-cysteinyl L-cysteine persulfido bis-L-glutamato L-histidino nickel triiron disulfide trioxide.


light absorption

The reception of a photon by a cell.


regulation of emodin biosynthetic process

Any process that modulates the frequency, rate or extent of emodin biosynthetic process.


ribosome localization

A process in which a ribosome is transported to, and/or maintained in, a specific location.


galactarate catabolic process

The chemical reactions and pathways resulting in the breakdown of galactarate, the anion of galactaric acid.


Catalysis of the reaction: 4-aminobenzoate + L-glutamate + ATP <=> H+ + p-aminobenzoyl glutamate + AMP + diphosphoric acid.


response to mitotic cell cycle spindle assembly checkpoint signaling

A process that occurs in response to signals generated as a result of mitotic cell cycle spindle assembly checkpoint signaling.


Catalysis of the reaction: H+ + leukotriene E(4) + NADPH + O2 = 20-hydroxy-leukotriene E(4) + H2O + NADP+.


glyceraldehyde dehydrogenase (NADP) activity

Catalysis of the reaction: D-glyceraldehyde + H2O + NADP+ = D-glycerate + NADPH + H+.


submerged biofilm formation

A process in which planktonically growing microorganisms aggregate and grow on solid substrates under the flow of a liquid and produce extracellular polymers that facilitate attachment and matrix formation, resulting in a change in the organisms' growth rate and gene transcription.


cotyledon vascular tissue pattern formation

Vascular tissue pattern formation as it occurs in the cotyledon of vascular plants.


negative regulation of planar cell polarity pathway involved in neural tube closure

Any process that stops, prevents, or reduces the frequency, rate or extent of planar cell polarity pathway involved in neural tube closure.


Catalysis of the reaction: DNA with 1-N6-ethenoadenine + H2O = DNA with abasic site + 1-N6-ethenoadenine. This reaction is the removal of 1,N6-ethenoadenine by cleaving the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar.


Catalysis of the reaction: esculetin + UDP-alpha-D-glucose <=> 3-O-beta-D-glucosyl-esculetin + UDP + H+.


delphinidin 3-O-glucoside 5-O-glucosyltransferase (acyl-glucose dependent) activity

Catalysis of the reaction: delphinidin 3-O-beta-D-glucoside + 1-O-vanilloyl-beta-D-glucose <=> delphinidin 3-O-beta-D-glucoside-5-O-beta-D-glucoside betaine + vanillate + H+.


selenoneine metabolic process

The chemical reactions and pathways involving selenoneine.


glossopharyngeal nerve formation

The process that gives rise to the glossopharyngeal nerve. This process pertains to the initial formation of a structure from unspecified parts. Various sensory and motor branches of the glossopharyngeal nerve supply nerve connections to the pharynx and back of the tongue. The branchial motor component contains motor fibers that innervate muscles that elevate the pharynx and larynx, and the tympanic branch supplies parasympathetic fibers to the otic ganglion.


cytidine biosynthetic process

The chemical reactions and pathways resulting in the formation of cytidine, cytosine riboside, a widely distributed nucleoside.


heptose 7-phosphate kinase activity

Catalysis of the reaction: D-alpha,beta-D-heptose-7-phosphate + ATP = D-beta-D-heptose-1,7-bisphosphate + ADP.


kinetin UDP glycosyltransferase activity

Catalysis of the reaction: UDP-alpha-D-glucose + kinetin <=> H+ + 9-(alpha-D-glucosyl)kinetin + UDP.


Catalysis of the reaction: NAD+ + 2-dehydro-3-deoxy-D-gluconate = NADH + (4S)-4,6-dihydroxy-2,5-dioxohexanoate.


canonical Wnt signaling pathway involved in positive regulation of cell-cell adhesion

The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes involved in the positive regulation of cell to cell adhesion.


mesencephalic trigeminal nucleus development

The process whose specific outcome is the progression of the mesencephalic trigeminal nucleus over time, from its formation to the mature structure.


regulation of sexual sporulation

Any process that modulates the frequency, rate or extent of spore formation from the products of meiosis. An example of this is found in Saccharomyces cerevisiae.


peptide antibiotic metabolic process

The chemical reactions and pathways involving peptides with antibiotic activity.


CGC codon-amino acid adaptor activity

A triplet codon-amino acid adaptor activity that recognizes a CGC codon.


histone H2AK9 acetyltransferase activity

Catalysis of the reaction: acetyl-CoA + histone H2A L-lysine (position 9) = CoA + histone H2A N6-acetyl-L-lysine (position 9).


erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process

The chemical reactions and pathways involving erythrose 4-phosphate/phosphoenolpyruvate family amino acid.


positive regulation of corticosteroid hormone secretion

Any process that activates or increases the frequency, rate or extent of corticosteroid hormone secretion.


regulation of metanephric comma-shaped body morphogenesis

Any process that modulates the frequency, rate or extent of metanephric comma-shaped body morphogenesis.


Catalysis of the reaction: D-fructose + D-glucose = D-glucitol + D-glucono-1,5-lactone.


pterocarpan reductase activity

Catalysis of the reaction: H+ + (-)-medicarpin + NADPH = (+)-vestitol + NADP.


5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate metabolic process

The chemical reactions and pathways involving 5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate.


vulval cell fate commitment

The process in which the cellular identity of nematode vulval cells is acquired and determined. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed adult vulva, which is the egg-laying organ of female and hermaphrodite nematodes.


Catalysis of the reaction: myricetin 3-O-beta-D-glucopyranoside + UDP-alpha-D-glucose <=> myricetin 3-O-gentiobioside + UDP + H+.


maintenance of inflorescence meristem identity

The process in which an organism retains a population of inflorescence meristem cells, preventing the commitment of all stem cell progeny to a differentiated cell fate.


acetylenecarboxylate hydratase activity, producing 3-hydroxypropenoate

Catalysis of the reaction: 3-hydroxypropenoate = propynoate + H2O.


photomorphogenesis

The control of plant growth, development, and differentiation by the duration and nature of light, independent of photosynthesis.


compound eye corneal lens development

The process whose specific outcome is the progression of the corneal lens in the compound eye over time, from its formation to the mature structure. The corneal lens is a chitinous extracellular secretion of the four underlying cone cells and the pigment cells.


response to increased oxygen levels

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting an increase in the level of oxygen.


isogloboside biosynthetic process

The chemical reactions and pathways resulting in the formation of a lactosyl-ceramide derivative in which a galactose is linked to the galactose via an alpha 1,3 linkage (vs alpha 1,4 for globosides).


RNA polymerase II C-terminal domain S5 O-GlcNAc transferase activity

Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + RNA polymerase II large subunit CTD heptapeptide repeat (YSPTSPS) = UDP + RNA polymerase II large subunit CTD heptapeptide repeat 3-O-(N-acetyl-D-glucosaminyl)-L-serine (position 5).


lateral mesodermal cell fate determination

The process in which a cell becomes capable of differentiating autonomously into a lateral mesoderm cell regardless of its environment; upon determination, the cell fate cannot be reversed.


inferior olivary nucleus morphogenesis

The process in which the anatomical structure of the inferior olivary nucleus is generated and organized. The inferior olivary nucleus is a capsule-shaped structure in the ventral medulla located just lateral and dorsal to the medullary pyramids. Neurons in the inferior olivary nucleus are the source of climbing fiber input to the cerebellar cortex; these neurons have been implicated in various functions, such as learning and timing of movements.


tetrahydrofuran metabolic process

The chemical reactions and pathways involving tetrahydrofuran, a cyclic 4 carbon ether. It is one of the most polar ethers and is a widely used solvent for polar reagents. Since THF is very soluble in water and has a relatively low boiling point, significant amounts are often released into the environment, causing contamination problems.


L-sorbose metabolic process

The chemical reactions and pathways involving sorbose, the L-enantiomer of the ketohexose xylo-2-hexulose. L-sorbose is formed by bacterial oxidation of sorbitol.


2-dehydropantolactone reductase (A-specific) activity

Catalysis of the reaction: (R)-pantolactone + NADP+ = 2-dehydropantolactone + NADPH + H+. The reaction is A-specific (i.e. the pro-R hydrogen is transferred from the 4-position of reduced nicotinamide cofactor) with respect to NADP+.


negative regulation of neural crest cell differentiation

Any process that stops, prevents or reduces the frequency, rate or extent of neural crest cell differentiation.


cellular response to undecane

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an undecane stimulus.


leucokinin receptor activity

Combining with a leucokinin, any of several octapeptide hormones found in insects, and transmitting the signal to initiate a change in cell activity.


[dermatan sulfate]-L-iduronyl 2-Osulfotransferase activity

Catalysis of the reaction: 3'-phosphonato-5'-adenylyl sulfate + [dermatan]-alpha-L-iduronate <=> adenosine 3',5'-bismonophosphate + [dermatan-sulfate]-2-O-sulfo-alpha-L-iduronate.


R2/R5 development

The process whose specific outcome is the progression of the R2 and R5 pair of photoreceptors in the eye over time, from their formation to the mature structures. R2 and R5 are paired photoreceptors that contribute to the outer rhabdomeres. An example of this process is found in Drosophila melanogaster.


diadenylate cyclase activity

Catalysis of the reaction: 2 ATP = 3',3'-c-di-AMP + 2 diphosphate.


carbon-monoxide dehydrogenase (acceptor) activity

Catalysis of the reaction: CO + H2O + acceptor = CO2 + reduced acceptor.


testicular fusome organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the fusome of testicular cells, an organelle derived from the spectrosome.


positive regulation of embryonic skeletal joint development

Any process that activates or increases the frequency, rate or extent of embryonic skeletal joint development.


cyanate hydratase activity

Catalysis of the reaction: cyanate + H2O = carbamate.


G protein-coupled neurotransmitter receptor activity

Combining with a neurotransmitter and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.


FMN metabolic process

The chemical reactions and pathways involving FMN, riboflavin 5'-(dihydrogen phosphate), a coenzyme for a number of oxidative enzymes including NADH dehydrogenase.


cellular response to diphenidol

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diphenidol stimulus.


kidney cortex tubule cell dedifferentiation

The process in which a kidney cortex tubule cell (specialized epithelial cell of the kidney) loses the structural or functional features that characterize it in the mature organism, or some other relatively stable phase of the organism's life history. Under certain conditions, these cells can revert back to the features of the stem cells that were their ancestors.


positive regulation of lipoprotein particle clearance

Any process that increases the rate, frequency, or extent of lipoprotein particle clearance. Lipoprotein particle clearance is the process in which a lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.


antigen sampling by dendritic cells in mucosal-associated lymphoid tissue

The process of antigen sampling carried out by dendritic cells in the mucosal-associated lymphoid tissue.


negative regulation of cell adhesion involved in single-species biofilm formation

Any process that stops, prevents or reduces the frequency, rate or extent of cell adhesion involved in single-species biofilm formation.


macrophage inflammatory protein-1 alpha production

The appearance of macrophage inflammatory protein 1 alpha due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


pore-mediated entry of viral genome into host cell

Injection by a non-enveloped virus of the viral genome into the host cytoplasm through creation of a pore or channel in the host cell membrane(s). Usually mediated by a viral pore-forming peptide associated with the viral capsid or bacteriophage tail.


cranial nerve maturation

A developmental process, independent of morphogenetic (shape) change, that is required for a cranial nerve to attain its fully functional state. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions.


oxysterol transfer activity

Removes oxysterol from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle.


proximal straight tubule development

The process whose specific outcome is the progression of the proximal straight tubule over time, from its formation to the mature structure. The proximal straight tubule is the part of the descending limb that extends from the proximal convoluted tubule to the descending thin tubule.


3',3'-cyclic GMP-AMP synthase activity

Catalysis of the reaction: ATP + GTP = 2 diphosphate + cyclic G-P(3'-5')A-P(3'-5') (cyclic 3',3' GAMP).


The chemical reactions and pathways involving 7,8-didemethyl-8-hydroxy-5-deazariboflavin.


Catalysis of the reaction: meso-2,6-diaminopimelate + ATP + UDP-N-acetylmuramoyl-L-alanyl-D-glutamate = ADP + 2 H+ + phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-gamma-glutamyl-meso-2,6-diaminoheptanedioate.


ATPase-coupled L-glutamate tranmembrane transporter activity

Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + L-glutamate(out) -> ADP + phosphate + L-glutamate(in).


modulation by symbiont of host transcription

Any process in which an organism modulates the frequency, rate or extent of its host's transcription. The host is defined as the larger of the organisms involved in a symbiotic interaction.


ferrichrome transmembrane transporter activity

Enables the directed movement of a ferrichrome from one side of a membrane to the other. Ferrichromes are any of a group of growth-promoting Fe(III) chelates formed by various genera of microfungi. They are homodetic cyclic hexapeptides made up of a tripeptide of glycine (or other small neutral amino acids) and a tripeptide of an N'acyl-N4-hydroxy-L-ornithine.


apocarotenoid metabolic process

The chemical reactions and pathways involving apocarotenoids, a class of compounds derived from the oxidative cleavage of carotenoids, many of which are biologically important e.g. retinal and abscisic acid.


antigen processing and presentation following macropinocytosis

Antigen processing and presentation which is initiated by uptake of antigen via macropinocytosis.


juxtaglomerulus cell fate commitment

The process in which the developmental fate of a cell becomes restricted such that it will develop into a juxtaglomerulus cell.


regulation of meristem structural organization

Any process that modulates the frequency, rate or extent of meristem organization.


Catalysis of the reaction: 1-18:3-2-18:2-phosphatidylcholine + O2 + a reduced electron acceptor <=> 1-18:3-2-18:3-phosphatidylcholine + 2 H2O + an oxidized electron acceptor.


thiamine diphosphate dephosphorylation

The removal of one or more phosphate groups from thiamine diphosphate, a derivative of thiamine (vitamin B1) which acts as a coenzyme in a range of processes including the Krebs cycle.


cell proliferation involved in heart valve morphogenesis

The multiplication or reproduction of cells that contributes to the shaping of a heart valve.


negative regulation of toll-like receptor 15 signaling pathway

Any process that stops, prevents or reduces the frequency, rate or extent of toll-like receptor 15 signaling pathway.


negative regulation of nuclear migration along microtubule

Any process that stops, prevents or reduces the frequency, rate or extent of nuclear migration along microtubule.


di-n-butyltin dioxygenase activity

Catalysis of the reaction: dibutyltin + O2 + 2 H+ + 2 e- = H2O + beta-hydroxybutylbutyltin.


regulation of carbohydrate metabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving carbohydrates.


halogenase activity

Catalysis of the reaction: R-CH + a halogen + oxygen donor = R-C-halogen +H2O.


Catalysis of the reaction: N-acetyl-L-glutamate 5-semialdehyde + NADP+ + phosphate = N-acetyl-5-glutamyl phosphate + NADPH + H+.


mating-type P-factor pheromone receptor activity

Combining with the mating-type peptide pheromone P-factor and transmitting the signal across the membrane to initiate a change in cell activity. P-factor is a polypeptide of 23 residues, with the sequence Thr-Tyr-Ala-Asp-Phe-Leu-Arg-Ala-Tyr-Gln-Ser-Trp-Asn-Thr-Phe-Val-Asn-Pro-Asp-Arg-Pro-Asn-Leu, and is a peptide pheromone released by Schizosaccharomyces pombe cells of the cellular mating type Plus.


Catalysis of the reaction: 1,2-dihydroxydibenzothiophene + O2 = cis-4-(2-(3-hydroxy)-thionaphthenyl)-2-oxo-3-butenoate.


3-chlorocatechol catabolic process

The chemical reactions and pathways resulting in the breakdown of 3-chlorocatechol.


24-methylenecycloartanol 4alpha-methyl oxidase activity

Catalysis of the reaction: 24-methylenecycloartanol + NADH + O2 + H+ <=> 4alpha-hydroxymethyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(241)-en-3beta-ol + NAD + H2O.


Catalysis of the reaction: 3-hydroxy-2-naphthoate + O2 = (3E)-3-[(6Z)-6-(carboxymethylene)cyclohexa-2,4-dien-1-ylidene]-2-oxopropanate.


establishment or maintenance of bipolar cell polarity regulating cell shape

Any cellular process that results in the specification, formation or maintenance of a bipolar intracellular organization or cell growth patterns that regulates the shaping of a cell.


galacturonate binding

Binding to a galacturonate. Galacturonate is the anion of galacturonic acid, the uronic acid formally derived from galactose by oxidation of the hydroxymethylene group at C-6 to a carboxyl group.


copper incorporation into copper-sulfur cluster

The incorporation of copper into a copper-sulfur cluster.


3-hexaprenyl-4-hydroxy-5-methoxybenzoic acid decarboxylase activity

Catalysis of the reaction: 3-hexaprenyl-4-hydroxy-5-methoxybenzoic acid -> 2-hexaprenyl-6-methoxyphenol + CO2.


xylan biosynthetic process

The chemical reactions and pathways resulting in the formation of xylan, a polymer containing a beta-1,4-linked D-xylose backbone.


CAA codon-amino acid adaptor activity

A triplet codon-amino acid adaptor activity that recognizes a CAA codon.


Catalysis of the reaction: S-adenosyl-L-methionine(1+) + L-tryptophan = S-adenosyl-L-homocysteine + L-2-methyltryptophan + H+.


vascular endothelial cell response to pulsatile fluid shear stress

Any response to pulsatile fluid shear stress that occurs in a vascular endothelial cell.


sarcosine N-methyltransferase activity

Catalysis of the reaction: S-adenosyl-L-methionine + sarcosine = S-adenosyl-L-homocysteine + N,N-dimethylglycine.


dorsal fin development

The process whose specific outcome is the progression of the dorsal fin over time, from its formation to the mature structure.


circadian regulation of systemic arterial blood pressure

Any process in which an organism modulates its blood pressure at different values with a regularity of approximately 24 hours.


(S)-2-hydroxy-fatty acid dehydrogenase activity

Catalysis of the reaction: (S)-2-hydroxystearate + NAD+ = 2-oxostearate + H+ + NADH.


altruistic, chimeric, non-reproductive fruiting body development

Development of a chimeric, non-reproductive fruiting body in which cells of all genotypes have an equal chance of becoming a spore cell.


Catalysis of the reaction: cis-2,3-dihydroxy-2,3-dihydro-p-cumate + NAD+ = 2,3-dihydroxy-p-cumate + H+ + NADH.


suppression of host RNAi-mediated antiviral immune response

Any process in which a symbiont stops, prevents, or reduces the rate or extent of the host's RNAi-mediated antiviral immune response. The host is defined as the larger of the organisms involved in a symbiotic interaction.


fructan beta-fructosidase activity

Catalysis of the hydrolysis of terminal, non-reducing 2,1- and 2,6-linked beta-D-fructofuranose residues in fructans.


tropine dehydrogenase activity

Catalysis of the reaction: NADP+ + tropine = H+ + NADPH + tropinone.


2-dehydro-3-deoxy-D-gluconic acid metabolic process

The chemical reactions and pathways involving 2-dehydro-3-deoxy-D-gluconic acid.


dibenzofuran 4,4a-dioxygenase activity

Catalysis of the reaction: dibenzofuran + NADH + H+ + O2 = 2,2',3-trihydroxybiphenyl + NAD+.


positive regulation of intermediate mesodermal cell fate specification

Any process that activates or increases the frequency, rate or extent of intermediate mesoderm cell fate specification.


negative regulation of ecdysone receptor-mediated signaling pathway

Any process that stops, prevents, or reduces the frequency, rate or extent of any ecdysone receptor-mediated signaling pathway.


positive regulation of xylose catabolic process to ethanol

Any process that activates or increases the frequency, rate or extent of xylose catabolic process to ethanol.


regulation of amino acid uptake involved in synaptic transmission

Any process that modulates the frequency, rate or extent of the directed movement of amino acid neurotransmitters into a neuron or glial cell.


ethanolamine catabolic process

The chemical reactions and pathways resulting in the breakdown of ethanolamine (2-aminoethanol), an important water-soluble base of phospholipid (phosphatidylethanolamine).


neuromedin K receptor activity

Combining with neuromedin K, the peptide Asp-Met-His-Asp-Phe-Phe-Val-Gly-Leu-Met to initiate a change in cell activity.


regulation of appressorium formation

Any process that modulates the frequency, rate or extent of symbiont appressorium formation.


suppression by virus of host cell wall biogenesis

Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of cell wall biogenesis in the host organism. Cell wall biogenesis includes the biosynthesis of constituent macromolecules, and the assembly and arrangement of these constituent parts.


substrate mycelium formation

The process by which, in some fungal species, hyphae grow as a network of invasive thread-like filaments formed from chains of attached cells within a solid or semi-solid substrate.


7-methylthiopropyl glucosinolate S-oxygenase activity

Catalysis of the reaction: 7-methylthiopropyl-glucosinolate = 7-methylsulfinylpropyl-glucosinolate.


histone H3K72 acetyltransferase activity

Catalysis of the reaction: acetyl-CoA + histone H3 L-lysine (position 72) = CoA + histone H3 N6-acetyl-L-lysine (position 72).


phragmoplast microtubule organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures formed of microtubules and associated proteins in phragmoplast, a plant cell specific structure that forms during late cytokinesis. Phragmoplast serves as a scaffold for cell plate assembly and subsequent formation of a new cell wall separating the two daughter cells.


positive regulation of canonical Wnt signaling pathway involved in neural crest cell differentiation

Any process that increases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin involved in neural crest cell differentiation. The Wnt signaling pathway is the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes.


D-2-hydroxy-acid dehydrogenase activity

Catalysis of the reaction: (R)-lactate + A = AH(2) + pyruvate.


2-oxopropyl-CoM reductase (carboxylating) activity

Catalysis of the reaction: acetoacetate + coenzyme M + NADP+ = 2-oxopropyl-coenzyme M + CO2 + NADPH.


endodermal-mesodermal cell signaling involved in heart induction

Any process that mediates the transfer of information from endodermal cells to mesodermal cells that contributes to heart induction.


mesangial cell fate commitment

The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesangial cell.


Catalysis of the reaction: trans-cyclohexane-1,2-diol + NAD+ = 2-hydroxycyclohexan-1-one + NADH.


ent-kaurene metabolic process

The chemical reactions and pathways involving ent-kaur-16-ene. Ent-kaurene is a tetracyclic diterpenoid that is a precursor of several plant isoprenoids, including gibberellins.


proline 3-hydroxylase activity

Catalysis of the reaction: L-proline + 2-oxoglutarate + O2 = cis-3-hydroxy-L-proline + succinate + CO2.


asperthecin metabolic process

The chemical reactions and pathways involving asperthecin, an anthraquinone pigment obtained from the mould Aspergillus nidulans.


baculum development

The reproductive developmental process whose specific outcome is the progression of the baculum over time, from its formation to the mature structure.


regulation of Malpighian tubule diameter

Ensuring that the Malpighian tubule is the correct width. Malpighian tubules have a uniform circumference along their length; the circumference of the tubes is eight cells during the time the cells are dividing, after which the cells rearrange producting tubes with a cirumference of two cells.


nicotinate metabolic process

The chemical reactions and pathways involving nicotinate.


amoeboid sperm motility

Any process involved in the controlled movement of an amoeboid sperm cell.


negative regulation of filamentous growth of a population of unicellular organisms

Any process that stops, prevents or reduces the frequency, rate or extent of filamentous growth of a population of unicellular organisms.


neural crest cell delamination

The negative regulation of cell adhesion process in which a neural crest cell physically separates from the rest of the neural tube.


envenomation resulting in negative regulation of voltage-gated potassium channel activity in another organism

A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant negative regulation of the activity of a voltage-gated potassium channel in the bitten/stung organism.


low-affinity tryptophan transmembrane transporter activity

Catalysis of the low-affinity transfer of L-tryptophan from one side of a membrane to the other. Tryptophan is 2-amino-3-(1H-indol-3-yl)propanoic acid. In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations.


mannoprotein metabolic process

The chemical reactions and pathways involving a mannoprotein, a protein that contains covalently bound mannose residues.


Catalysis of the 3-O-acetylation of a trichothecene. Trichothecenes are sesquiterpene epoxide mycotoxins that act as potent inhibitors of eukaryotic protein synthesis.


ferulate metabolic process

The chemical reactions and pathways involving ferulate, (2E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoate.


alginic acid metabolic process

The chemical reactions and pathways involving alginic acid, a hydrophilic polysaccharide occurring in, for example, the cell walls of brown algae (brown seaweeds).


nitrobenzene biosynthetic process

The chemical reactions and pathways resulting in the formation of nitrobenzene.


cerebellar molecular layer maturation

A developmental process, independent of morphogenetic (shape) change, that is required for the cerebellar molecular layer to attain its fully functional state. The molecular layer is the outermost layer of the cerebellar cortex. It contains the parallel fibers of the granule cells, interneurons such as stellate and basket cells, and the dendrites of the underlying Purkinje cells.


(4S)-limonene synthase activity

Catalysis of the reaction: geranyl diphosphate = (4S)-limonene + diphosphate.


heme O metabolic process

The chemical reactions and pathways involving heme O, a derivative of heme containing a 17-carbon hydroxyethylfarnesyl side chain at position 8 of the tetrapyrrole macrocycle.


negative regulation of cellotriose transport

Any process that stops, prevents or reduces the frequency, rate or extent of cellotriose transport.


xylene monooxygenase activity

Catalysis of the reactions: toluene + 1/2 O2 = benzyl alcohol, and xylene + 1/2 O2 = methylbenzyl alcohol.


response to DNA integrity checkpoint signaling

A process that occurs in response to signals generated as a result of DNA integrity checkpoint signaling.


cranial ganglion formation

The process that gives rise to a cranial ganglion. This process pertains to the initial formation of a structure from unspecified parts.


ABC-type cysteine transporter activity

Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + cysteine(out/in) = ADP + phosphate + cysteine(in/out).


response to streptomycin

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a streptomycin stimulus. Streptomycin is a commonly used antibiotic in cell culture media which acts only on prokaryotes and blocks transition from initiation complex to chain elongating ribosome.


transferase activity, transferring phosphorus-containing groups

Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to another (acceptor).


regulation of stomatal opening

Any process that modulates the frequency, rate or extent of stomatal opening.


Catalysis of the reaction: S-adenosyl-L-methionine(1+) + demethylmacrocin = S-adenosyl-L-homocysteine + H+ + macrocin.


cotyledon development

The process whose specific outcome is the progression of the cotyledon over time, from its formation to the mature structure. The cotyledon is the modified leaf (seed leaf), found as part of the embryo in plant seeds. It is involved in either storage or absorption of food reserves. Dicotyledonous seeds contain two cotyledons, while monocotyledonous seeds contain only one. The cotyledons may appear above ground and show photosynthetic activity in the seedling.


positive regulation of extrathymic T cell differentiation

Any process that activates or increases the frequency, rate or extent of extrathymic T cell differentiation.


amino acid activation

The modification of an amino acid to an active form, for incorporation into a peptide, protein or other macromolecule.


crotonobetaine-CoA ligase activity

Catalysis of the reaction: CoA + crotono-betaine + ATP = AMP + diphosphate + crotonobetainyl-CoA.


oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond

Catalysis of an oxidation-reduction (redox) reaction in which X-H and Y-H form X-Y.


envenomation resulting in modulation of sensory perception of pain in another organism

A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the modulation of the sensory perception of pain in the bitten organism.


regulation of response to stress

Any process that modulates the frequency, rate or extent of a response to stress. Response to stress is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).


glutamate synthase activity

Catalysis of the formation of L-glutamine and 2-oxoglutarate from L-glutamate, using NADH, NADPH or ferredoxin as hydrogen acceptors.


protein-keratan sulfate linkage via keratan sulfate D-glucuronyl-D-galactosyl-D-galactosyl-D-xylosyl-L-threonine

Keratan sulfate components are covalently linked to a core glycoprotein via O-glycosidic linkages between xylose and threonine residues.


Catalysis of the reaction: 3,3',4',5,7,8-hexahydroxyflavone + S-adenosyl-L-methionine(1+) = 3,3',4',5,7-pentahydroxy-8-methoxyflavone + S-adenosyl-L-homocysteine + H+.


Catalysis of the reaction: 5-carboxymethyl-2-hydroxymuconate = 5-carboxy-2-oxohept-3-enedioate.


dCMP metabolic process

The chemical reactions and pathways involving dCMP, deoxycytidine monophosphate.


carotene 7,8-desaturase activity

Catalysis of the reaction: neurosporene + donor-H2 + O2 = lycopene + acceptor + 2 H2O.


muscle hypertrophy in response to stress

The enlargement or overgrowth of all or part of a muscle organ or tissue due to an increase in the size of its muscle cells as a result of a disturbance in organismal or cellular homeostasis.


transmitter-gated monoatomic ion channel activity

Enables the transmembrane transfer of an ion by a channel that opens when a specific neurotransmitter has been bound by the channel complex or one of its constituent parts.


chemokine (C-C motif) ligand 2 signaling pathway

The series of molecular signals initiated by the binding of the C-C chemokine CCL2 to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.


DNA beta-glucosyltransferase activity

Catalysis of the transfer of a beta-D-glucosyl residue from UDP-glucose to a hydroxymethylcytosine residue in DNA.


regulation of L-dopa decarboxylase activity

Any process that modulates the frequency, rate or extent of L-dopa decarboxylase activity.


1-18:2-2-18:2-sn-glycerol-3-phosphocholine desaturase activity (SN2-18:3 forming)

Catalysis of the reaction: 1-18:2-2-18:2-sn-glycerol-3-phosphocholine + O2 + a reduced electron acceptor = 1-18:2-2-18:3-phosphatidylcholine + 2 H2O + an oxidized electron acceptor.


protein dehydration

The removal of a water group from a protein amino acid.


2-naphthoate CoA-transferase activity

Catalysis of the reaction: 2-naphthoyl-CoA + OH- = 2-naphthoate + CoASH.


tungsten incorporation into metallo-sulfur cluster

The incorporation of tungsten into a metallo-sulfur cluster.


negative regulation of mannotriose transport

Any process that stops, prevents or reduces the frequency, rate or extent of mannotriose transport.


carbon catabolite repression

A process in which the presence of one carbon source leads to the modulation of the frequency, rate, or extent of the metabolism of other carbon sources.


Catalysis of the reaction: 1-hydroxy-2-naphthaldehyde + NAD+ + H2O = NADH + H+ + 1-hydroxy-2-naphthoate.


head kidney formation

The developmental process pertaining to the initial formation of the head kidney. The head kidney is a pronephros that consists of fused bilateral lobes located in the anterior part of the kidney.


sulfolactate sulfo-lyase activity

Catalysis of the reaction: 3-sulfolactate = pyruvate + sulfite.


regulation of small intestine smooth muscle contraction

Any process that modulates the frequency, rate or extent of small intestine smooth muscle contraction.


lactate dehydrogenase activity

Catalysis of the reaction: lactate + NAD+ = H+ + NADH + pyruvate.


pancreatic D cell development

The process whose specific outcome is the progression of a pancreatic delta cell over time, from its formation to the mature structure. A delta cell is a cell of the pancreas that produces somatostatin.


Catalysis of the reaction: 2-dehydro-3-deoxy-D-gluconate + NADP+ = (4S,5S)-4,5-dihydroxy-2,6-dioxohexanoate + H+ + NADPH.


regulation of antral ovarian follicle growth

Any process that modulates the frequency, rate or extent of antral ovarian follicle growth.


Catalysis of the reaction: 2,3-dihydroxybiphenyl + O2 = 2-hydroxy-6-phenylhexa-2,4-dienoic acid.


2,4-dichlorobenzoate catabolic process

The chemical reactions and pathways resulting in the breakdown of 2,4-dichlorobenzoate, a chlorinated aromatic compound which is a key intermediate in the aerobic degradation of polychlorinated biphenyls (PCBs).


nephron tubule development

The progression of a nephron tubule over time, from its initial formation to the mature structure. A nephron tubule is an epithelial tube that is part of the nephron, the functional part of the kidney.


dhurrin biosynthetic process

The chemical reactions and pathways resulting in the formation of dhurrin, a cyanogenic glucoside which functions as a plant defense compound.


chalcone isomerase activity

Catalysis of the reaction: a chalcone = a flavanone.


RNA ligase activity

Catalysis of the formation of a phosphodiester bond between a hydroxyl group at the end of one RNA chain and the 5'-phosphate group at the end of another.


head kidney development

The process whose specific outcome is the progression of the head kidney over time, from its formation to the mature structure. The head kidney is a pronephros that consists of fused bilateral lobes located in the anterior part of the kidney. It is analogous to the mammalian bone marrow and the primary site of definitive hematopoiesis.


regulation of positive chemotaxis to cAMP by DIF-1

Any process that modulates the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of DIF-1. DIF-1 is a chlorinated alkylphenone.


regulation of mammary gland involution

Any process that modulates the frequency, rate or extent of mammary gland involution.


all-trans-neoxanthin catabolic process

The chemical reactions and pathways resulting in the breakdown of all-trans-neoxanthin.


sulfur:ferric ion oxidoreductase activity

Catalysis of the reaction: a perthiol + 4 Fe3+ + 3 H2O = sulfite + a thiol + 4 Fe2+ + 8 H+.


alpha-beta intraepithelial T cell differentiation

The process in which a precursor cell type acquires the specialized features of an alpha-beta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways.


oxytetracycline metabolic process

The chemical reactions and pathways involving oxytetracycline.


zeatin metabolic process

The chemical reactions and pathways involving zeatin, 2-methyl-4-(9H-purin-6-ylamino)but-2-en-1-ol.


netrin receptor activity involved in chemoattraction

Combining with a netrin signal and transmitting the signal from one side of the membrane to the other to contribute to the directed movement of a motile cell towards a higher concentration of netrin.


stevioside glucosyltransferase activity (rebaudioside A forming)

Catalysis of the reaction: stevioside + UDP-alpha-D-glucose = rebaudioside A + UDP + H+.


Catalysis of the reaction: 7-O-methylmyricetin + S-adenosyl-L-methionine <=> 7,4'-dimethylmyricetin + S-adenosyl-L-homocysteine + H+.


branched-chain dodecylbenzene sulfonate monooxygenase activity

Catalysis of the reaction: branched-chain dodecylbenzene sulfonate + 1/2 O2 + H+ = sulfurous acid + branched-chain dodecyl-4-hydroxy-benzene + sulfite.


growth plate cartilage chondrocyte division

The process resulting in the oriented physical partitioning and separation of a chondrocytes in the growth plate.


plastid outer membrane organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the outer membrane of a plastid.


substrate-dependent cerebral cortex tangential migration

The process where neuronal precursors migrate tangentially in the cerebral cortex, primarily guided through physical cell-cell interactions.


phosphagen metabolic process

The chemical reactions and pathways involving phosphagen, any of a group of guanidine phosphates that occur in muscle and can be used to regenerate ATP from ADP during muscular contraction.


positive regulation of vein smooth muscle contraction

Any process that increases the frequency, rate or extent of vein smooth muscle contraction.


regulation of compound eye photoreceptor development

Any process that modulates the frequency, rate or extent of compound eye photoreceptor development.


ATPase-coupled 2-aminoethylphosphonate transporter activity

Enables the directed movement of 2-aminoethylphosphonate from one side of a membrane to the other by catalysis of the reaction: ATP + H2O + 2-aminoethylphosphonate(out) = ADP + phosphate + 2-aminoethylphosphonate(in).


H3-H4 histone complex chaperone activity

A histone chaperone that carries a H3-H4 histone complex.


glial cell-derived neurotrophic factor production

The regulated release of glial cell line-derived neurotrophic factor from a cell. Glial cell-derived neurotrophic factor (GDNF) is a small protein that potently promotes the survival of many types of neurons, notably dopaminergic and motor neurons.


T-helper 1 cell chemotaxis

The directed movement of a T-helper 1 cell in response to an external stimulus.


(+)-thujopsene synthase activity

Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate <=> (+)-thujopsene + diphosphoric acid.


3-oxoacid decarboxylase activity

Catalysis of the reaction: H+ + a 3-oxoacid = carbon dioxide + a methylketone.


positive regulation of apoptotic process in another organism

Any process in which an organism activates, maintains or increases the frequency, rate or extent of programmed cell death by apoptosis in a second organism.


transcription regulatory region RNA binding

Binding to a RNA region within the transcript that regulates the transcription of a gene, cistron, or operon.


mitochondrial gene expression

The process in which a mitochondrial gene's sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.


hydrogen peroxide mediated signaling pathway involved in stomatal movement

Any hydrogen peroxide mediated signaling pathway that is involved in stomatal movement.


detoxification

Any process that reduces or removes the toxicity of a toxic substance. These may include transport of the toxic substance away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance.


regulation of antifungal innate immune response

Any process that modulates the frequency, rate or extent of an antifungal innate immune response.


response to oxygen-containing compound

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxygen-containing compound stimulus.


(S)-3-O-geranylgeranylglyceryl phosphate synthase activity

Catalysis of the alkylation of the primary hydroxyl group in (S)-glyceryl phosphate by geranylgeranyl diphosphate to form (S)-3-O-geranylgeranylglyceryl phosphate.


xanthosine biosynthetic process

The chemical reactions and pathways resulting in the formation of xanthosine.


Catalysis of the reaction: indole-3-butyrate + UDP-D-glucose = indole-3-butyryl-beta-1-D-glucose + UDP.


neural crest cell fate determination

The process in which a cell becomes capable of differentiating autonomously into a neural crest cell regardless of its environment; upon determination, the cell fate cannot be reversed.


specification of plant organ identity

The regionalization process in which the identity of a plant organ primordium is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized.


negative regulation of canonical Wnt signaling pathway involved in neural crest cell differentiation

Any process that decreases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin involved in neural crest cell differentiation. The Wnt signaling pathway is the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes.


nitric oxide reductase activity

Catalysis of the reaction: H2O + 2 ferricytochrome c + nitrous oxide = 2 H+ + 2 ferrocytochrome c + 2 nitric oxide.


styrene metabolic process

The chemical reactions and pathways involving styrene, an aromatic hydrocarbon liquid soluble in ether and alcohol. When heated, exposed to light or added to a peroxide catalyst, it undergoes polymerization to form polystyrene, a versatile material used in the manufacture of plastics, synthetic rubber, thermal insulation, and packaging. Styrene is a classified mutagen and a suspected carcinogen.


adenosine 3',5'-bisphosphate transmembrane transporter activity

Enables the transfer of adenosine 3',5'-bisphosphate from one side of a membrane to the other.


actin filament severing activity

Binding to an actin subunit and promoting its dissociation from an actin filament by a local change in actin subunit conformation and orientation, and severing of filaments.


austinol biosynthetic process

The chemical reactions and pathways resulting in the formation of austinol.


response to palmitoleic acid

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a palmitoleic acid stimulus.


orlandin biosynthetic process

The chemical reactions and pathways resulting in the formation of orlandin.


hypothalamus gonadotrophin-releasing hormone neuron fate commitment

The process in which the developmental fate of a cell becomes restricted such that it will develop into a hypothalamus neuron that releases gonadotrophin-releasing hormone.


Catalysis of the reaction: acetyl phosphate + sulfite = phosphate + sulfoacetaldehyde.


organic substance biosynthetic process

The chemical reactions and pathways resulting in the formation of an organic substance, any molecular entity containing carbon.


Catalysis of the reaction: 2-(R)-hydroxypropyl-coenzyme M + NAD+ = 2-oxopropyl-coenzyme M + H+ + NADH.


Sertoli cell barrier remodeling

The tissue remodeling process by which the Sertoli cell barrier is temporarily disrupted and reorganized to accommodate the transit of preleptotene spermatocytes at stage VIII of the epithelial cycle.


positive regulation of torso signaling pathway

Any process that activates or increases the frequency, rate or extent of the torso signaling pathway.


analia development

The process whose specific outcome is the progression of the analia over time, from its formation to the mature structure. The analia is the posterior-most vertral appendage that develops from the genital disc. An example of this process is analia development in Drosophila melanogaster.


regulation of thymocyte apoptotic process

Any process that modulates the occurrence or rate of thymocyte death by apoptotic process.


glycerol-1-phosphate dehydrogenase [NADP+] activity

Catalysis of the reaction: NADP+ + sn-glycerol 1-phosphate = dihydroxyacetone phosphate + H+ + NADPH.


N-methylalanine dehydrogenase activity

Catalysis of the reaction: N-methyl-L-alanine + H2O + NADP+ = H+ + methylammonium + NADPH + pyruvate.


vancomycin metabolic process

The chemical reactions and pathways involving vancomycin, (3S,6R,7R,11R,23S,26S,30aS,36R,38aR)-44-[2-O-(3-amino-2,3,6-trideoxy-3-C-methyl-alpha-L-lyxo-hexopyranosyl)-beta-D-glucopyranosyloxy]-3-(carbamoylmethyl)-10,19-dichloro-2,3,4,5,6,7,23,25,26,36,37,38,38a-tetradecahydro-7,22,28,30,32-pentahydroxy-6-(N-methyl-D-leucyl)-2,5,24,38,39-pentaoxo-1H,22H-23,36-(epiminomethano)-8,11:18,21-dietheno-13,16:31,35-di(metheno)[1,6,9]oxadiazacyclohexadecino[4,5-m][10,2,16]benzoxadiazacyclotetracosine-26-carboxylic acid, a complex glycopeptide from Streptomyces orientalis that inhibits a specific step in the synthesis of the peptidoglycan layer in Gram-positive bacteria.


pattern specification involved in mesonephros development

Any developmental process that results in the creation of defined areas or spaces within the mesonephros to which cells respond and eventually are instructed to differentiate.


gamma-tocopherol cyclase activity

Catalysis of the reaction: 2,3-dimethyl-6-phytyl-1,4-benzoquinone = gamma-tocopherol.


negative regulation by virus of host cell division

Any process where an infecting virus stops, prevents, or reduces the frequency, rate or extent of its host's cell division.


regulatory ncRNA 3'-end processing

Any process involved in forming the mature 3' end of a regulatory non-coding RNA molecule.


polytene chromosome puffing

The decondensing (loosening) and swelling of the chromosomal sites of target genes on polytene chromosomes following response to a stimulus, to facilitate sudden bursts of transcriptional activity in response to transient environmental signals.


histone H3S57 kinase activity

Catalysis of the reaction: histone H3-serine (position 57) + ATP = histone H3-phosphoserine (position 57) + ADP. This reaction is the addition of a phosphate group to the serine residue at position 57 of histone H3.


regulation of seedling development

Any process that modulates the frequency, rate or extent of seedling development.


Catalysis of the random hydrolysis of (1->6)-alpha-D-mannosidic linkages in unbranched (1->6)-mannans.


anterior lateral line neuromast primordium migration

The migration of a cluster of a relatively undifferentiated cell along the developing anterior lateral line, originating from cranial ectodermal placodes situated between the eye and the ear. The neuromast primordium deposits proneuromasts along the lateral line, from which the neuromasts will develop.


hippocampal pyramidal neuron differentiation

The process in which a relatively unspecialized cell acquires specialized features of a hippocampal pyramidal neuron, a pyramidal cell of the hippocampus.


4-coumaroyl 2'-hydroxylase activity

Catalysis of the reaction: 4-coumaryl-CoA + 2-oxoglutarate + O2 <=> 2,4-dihydroxycinnamoyl-CoA + succinate + carbon dioxide.


difructose-anhydride synthase activity

Catalysis of the reaction: H2O + bis-D-fructose 2',1:2,1'-dianhydride = inulobiose.


regulation of hypoxanthine transport

Any process that modulates the frequency, rate or extent of the directed movement of hypoxanthine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


Catalysis of the reaction: N-acetyl-beta-D-glucosaminyl-1,6-beta-D-(N-acetyl-B-glucosaminyl-1,2)-beta-D-mannosyl-R + UDP-N-acetyl-D-glucosamine = N-acetyl-beta-D-glucosaminyl-1,6-beta-D-(N-acetyl-D-glucosaminyl-1,2-beta)-(N-acetyl-D-glucosaminyl-1,4-beta)-D-mannosyl-R + UDP.


Catalysis of the reaction: 1-18:2-2-16:2-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor <=> 1-18:3-2-16:2-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor.


rubredoxin-NAD+ reductase activity

Catalysis of the reaction: reduced rubredoxin + NAD+ = oxidized rubredoxin + NADH + H+.


regulation of myeloid dendritic cell activation

Any process that modulates the frequency or rate of myeloid dendritic cell activation.


regulation of asexual sporulation

Any process that modulates the frequency, rate or extent of spore formation from the products of mitosis.


regulation of host-seeking behavior

Any process that modulates the frequency, rate or extent of any behavior associated with finding a host organism.


regulation of synergid differentiation

Any process that modulates the frequency, rate or extent of synergid cell differentiation.


alternate splicing of immunoglobulin genes

The generation of alternate transcripts of immunoglobulin genes through alternate splicing of exons.


Catalysis of the reaction: alanyl-poly(glycerolphosphate) + D-alanine + ATP = D-alanyl-alanyl-poly(glycerolphosphate) + phosphate + ADP.


ent-cassa-12,15-diene synthase activity

Catalysis of the reaction: ent-copalyl diphosphate = ent-cassa-12,15-diene + diphosphate.


D-valine metabolic process

The chemical reactions and pathways involving D-valine.


positive regulation of response to amylopectin

Any process that activates or increases the frequency, rate or extent of response to amylopectin.


cytochrome-c peroxidase activity

Catalysis of the reaction: 2 ferrocytochrome c + hydrogen peroxide = 2 ferricytochrome c + 2 H2O.


gap filling involved in double-strand break repair via nonhomologous end joining

Repair of the gaps in the DNA helix using a discontinuous template during double-strand break repair via nonhomologous end joining.


O-hydroxycinnamoyltransferase activity

Catalysis of the transfer of a hydroxycinnamoyl group to an oxygen atom on the acceptor molecule.


kaempferol O-glucoside metabolic process

The chemical reactions and pathways involving O-glucosylated derivatives of kaempferol.


D-cysteine catabolic process

The chemical reactions and pathways resulting in the breakdown of D-cysteine, (S)-2-amino-3-mercaptopropanoic acid, which occurs naturally in firefly luciferin.