positive regulation of primary miRNA processing

Any process that activates or increases the frequency, rate or extent of primary microRNA processing.


positive regulation of barbed-end actin filament capping

biolink:BiologicalProcess biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:Occurrent biolink:OntologyClass biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

Any process that activates or increases the frequency, rate or extent of barbed-end actin filament capping.


symbiont-mediated suppression of host chemokine signal transduction pathway

A process in which a symbiont interferes with, inhibits or disrupts a chemokine signaling pathway, a G protein-coupled receptor signal transduction pathway activated by a chemokine. The host is defined as the larger of the organisms involved in a symbiotic interaction.


positive regulation of high voltage-gated calcium channel activity

Any process that activates or increases the frequency, rate or extent of high voltage-gated calcium channel activity.


positive regulation of fibroblast migration

Any process that increases the rate, frequency or extent of fibroblast cell migration. Fibroblast cell migration is accomplished by extension and retraction of a pseudopodium.


positive regulation of hepatic stellate cell migration

Any process that increases the frequency, rate or extent of hepatic stellate cell migration.


3'-UTR-mediated mRNA destabilization

An mRNA destabilization process in which one or more RNA-binding proteins associate with the 3'-untranslated region (UTR) of an mRNA.


sperm end piece

biolink:CellularComponent biolink:AnatomicalEntity biolink:OrganismalEntity biolink:BiologicalEntity biolink:NamedThing biolink:PhysicalEssence biolink:SubjectOfInvestigation biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

The short tip of the sperm flagellum, adjacent to the sperm principal piece and furthest from the sperm head, which contains only the axoneme surrounded by the plasma membrane.


regulation of neutrophil activation

Any process that modulates the frequency, rate or extent of neutrophil activation.


negative regulation of neutrophil activation

Any process that stops, prevents or reduces the frequency, rate or extent of neutrophil activation.


positive regulation of neutrophil activation

Any process that activates or increases the frequency, rate or extent of neutrophil activation.


positive regulation of establishment of protein-containing complex localization to telomere

Any process that activates or increases the frequency, rate or extent of establishment of the localization of a protein-containing macromolecular complex to a telomere.


regulation of establishment of protein-containing complex localization to telomere

Any process that modulates the frequency, rate or extent of establishment of the localization of a protein-containing macromolecular complex to a telomere.


negative regulation of establishment of protein-containing complex localization to telomere

Any process that stops, prevents or reduces the frequency, rate or extent of establishment of the localization of a protein-containing macromolecular complex to a telomere.


response to L-glutamate

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an L-glutamate stimulus.


cellular response to L-glutamate

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-glutamate(1-) stimulus.


peroxisome membrane class-1 targeting sequence binding

biolink:MolecularActivity biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:Occurrent biolink:OntologyClass biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

Binding to a class I peroxisomal membrane targeting sequence, any of several sequences of amino acids within a protein that can act as a signal for the localization of the protein into the peroxisome membrane in a PEX19-dependent manner.


positive regulation of estrogen secretion

Any process that activates or increases the frequency, rate or extent of estrogen secretion.


Toc complex

Protein translocon complex at the chloroplast outer membrane.


positive regulation of syringal lignin catabolic process

Any process that activates or increases the frequency, rate or extent of syringal lignin catabolic process.


Kv4.3-KChIP1 channel complex

A voltage-gated potassium channel complex that contains the Kv channel interacting protein KChIP1 associated with the channel via interaction with the Kv alpha subunit 4.3.


type IV site-specific deoxyribonuclease activity

Catalysis of the endonucleolytic cleavage of DNA in a site specific manner. Cleavage is dependent on the presence of a specific recognition site in the DNA which must be modified (e.g. methylated, hydroxymethylated, glucosyl-hydroxymethylated).


negative regulation of single-strand break repair via homologous recombination

Any process that stops, prevents or reduces the frequency, rate or extent of single-strand break repair via homologous recombination.


negative regulation of telomere maintenance

Any process that stops, prevents, or reduces the frequency, rate or extent of a process that affects and monitors the activity of telomeric proteins and the length of telomeric DNA.


negative regulation of transcription by competitive promoter binding

Any process that stops, prevents, or reduces the frequency, rate or extent of DNA-dependent transcription using a mechanism that involves direct competition for interaction with a promoter binding site.


negative regulation of transcription by RNA polymerase III

Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase III.


negative regulation of pyruvate kinase activity

Any process that stops, prevents or reduces the frequency, rate or extent of pyruvate kinase activity.


negative regulation of poly(A)-specific ribonuclease activity

Any process that stops, prevents or reduces the frequency, rate or extent of poly(A)-specific ribonuclease activity.


negative regulation of double-strand break repair via single-strand annealing

Any process that stops, prevents or reduces the frequency, rate or extent of double-strand break repair via single-strand annealing.


negative regulation of exoribonuclease activity

Any process that stops, prevents or reduces the frequency, rate or extent of exoribonuclease activity.


negative regulation of exonucleolytic catabolism of deadenylated mRNA

Any process that stops, prevents, or reduces the frequency, rate or extent of exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay.


negative regulation of transcription elongation by RNA polymerase I

Any process that stops, prevents or reduces the frequency, rate or extent of transcription elongation mediated by RNA polymerase I.


negative regulation of termination of RNA polymerase I transcription

Any process that stops, prevents or reduces the frequency, rate or extent of termination of RNA polymerase I transcription.


symbiont-mediated suppression of host mRNA splicing

A process in which a symbiont inhibits or disrupts the splicing of host mRNA, thus interfering with normal host protein production. The host is defined as the larger of the organisms involved in a symbiotic interaction.


negative regulation of reciprocal meiotic recombination

Any process that decreases the frequency, rate or extent of recombination during meiosis. Reciprocal meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate.


negative regulation of transcription by transcription factor catabolism

Any process that stops, prevents, or reduces the frequency, rate or extent of DNA-dependent transcription using a mechanism that involves the catabolism of a sequence-specific DNA-binding transcription factor by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.


negative regulation of termination of DNA-templated transcription

Any process that decreases the rate, frequency or extent of DNA-dependent transcription termination, the process in which transcription is completed; the formation of phosphodiester bonds ceases, the RNA-DNA hybrid dissociates, and RNA polymerase releases the DNA.


negative regulation of telomere maintenance via semi-conservative replication

Any process that stops, prevents, or reduces the frequency, rate or extent of the semi-conservative replication of telomeric DNA.


negative regulation of ribosomal protein gene transcription from RNA polymerase II promoter in response to nutrient levels

Any process that decreases the frequency, rate or extent of the synthesis of RNA from ribosomal protein genes by RNA polymerase II, originating at an RNA polymerase II promoter, as a result of a stimulus reflecting the presence, absence, or concentration of nutrients.


negative regulation of mitotic recombination

Any process that inhibits or decreases the rate of DNA recombination during mitosis.


negative regulation of snoRNA metabolic process

Any process that stops, prevents or reduces the frequency, rate or extent of snoRNA metabolic process.


negative regulation of DNA ligation

Any process that stops, prevents, or reduces the frequency, rate or extent of DNA ligation, the re-formation of a broken phosphodiester bond in the DNA backbone, carried out by DNA ligase.


negative regulation of protection from non-homologous end joining at telomere

Any process that stops, prevents or reduces the frequency, rate or extent of protection from non-homologous end joining at telomere.


negative regulation of t-circle formation

Any process that stops, prevents or reduces the frequency, rate or extent of t-circle formation.


replication fork arrest at mating type locus

A process that impedes the progress of the DNA replication fork at natural replication fork pausing sites within the mating type locus.


negative regulation of purine nucleotide biosynthetic process

Any process that stops, prevents or reduces the frequency, rate or extent of purine nucleotide biosynthetic processes.


negative regulation of endoribonuclease activity

Any process that decreases the rate, frequency or extent of the catalysis of the hydrolysis of ester linkages within ribonucleic acid by creating internal breaks.


negative regulation of transcription elongation by RNA polymerase II

Any process that stops, prevents, or reduces the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides, catalyzed by RNA polymerase II.


negative regulation of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination

Any process that stops, prevents or reduces the frequency, rate or extent of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination.


negative regulation of NAD metabolic process

Any process that stops, prevents or reduces the frequency, rate or extent of NAD metabolic process.


negative regulation of apoptotic DNA fragmentation

Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic DNA fragmentation.


negative regulation of transcription of nucleolar large rRNA by RNA polymerase I

Any process that stops, prevents or reduces the frequency, rate or extent of transcription of nuclear large rRNA transcript mediated by RNA polymerase I.


negative regulation of telomere maintenance via telomere lengthening

Any process that stops, prevents or reduces the frequency, rate or extent of telomere maintenance via telomere lengthening.


negative regulation of reverse transcription

Any process that stops, prevents or reduces the frequency, rate or extent of reverse transcription.


negative regulation of error-prone translesion synthesis

Any process that stops, prevents or reduces the frequency, rate or extent of error-prone translesion synthesis.


negative regulation of double-strand break repair via nonhomologous end joining

Any process that stops, prevents or reduces the frequency, rate or extent of double-strand break repair via nonhomologous end joining.


negative regulation of ribosomal protein gene transcription from RNA polymerase II promoter in response to stress

Any process that decreases the frequency, rate or extent of the synthesis of RNA from ribosomal protein genes by RNA polymerase II, originating at an RNA polymerase II promoter, as a result of a disturbance in organismal or cellular homeostasis.


negative regulation of mitotic recombination-dependent replication fork processing

Any process that inhibits or decreases the rate of mitotic recombination-dependent replication fork processing. Suppression of recombination at replication forks is necessary to prevent template switching.


negative regulation of mitotic DNA replication initiation from late origin

Any process that stops, prevents or reduces the frequency, rate or extent of firing from a late origin of replication involved in mitotic DNA replication.


negative regulation of telomere single strand break repair

Any process that stops, prevents or reduces the frequency, rate or extent of telomere single strand break repair.


negative regulation of nuclease activity

Any process that stops or reduces the rate of nuclease activity, the hydrolysis of ester linkages within nucleic acids.


negative regulation of RNA polymerase II transcription preinitiation complex assembly

Any process that stops, prevents, or reduces the frequency, rate or extent of RNA polymerase II transcriptional preinitiation complex assembly.


negative regulation of DNA ligase activity

Any process that stops, prevents or reduces the frequency, rate or extent of DNA ligase activity.


negative regulation of pyrimidine nucleotide biosynthetic process

Any process that stops, prevents or reduces the frequency, rate or extent of pyrimidine nucleotide biosynthetic process.


carbon catabolite repression of transcription by galactose

A transcription regulation process in which the presence of galactose that leads to a decrease in the frequency, rate, or extent of transcription of specific genes involved in the metabolism of other carbon sources. Carbon catabolite repression is a mechanism of genetic regulation which the accumulation of catabolites of one substance in the cell represses the formation of enzymes that contribute to the catabolism of other substances.


negative regulation of glycolytic process

Any process that stops, prevents, or reduces the frequency, rate or extent of glycolysis.


negative regulation of telomere maintenance via telomerase

Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of telomeric repeats by telomerase.


negative regulation of guanylate cyclase activity

Any process that stops, prevents, or reduces the frequency, rate or extent of guanylate cyclase activity.


negative regulation of mRNA cis splicing, via spliceosome

Any process that stops, prevents or reduces the frequency, rate or extent of mRNA cis splicing, via spliceosome.


negative regulation of meiotic DNA double-strand break formation

Any process that stops, prevents or reduces the frequency, rate or extent of meiotic DNA double-strand break formation.


negative regulation of mRNA metabolic process

Any process that stops, prevents or reduces the frequency, rate or extent of mRNA metabolic process.


negative regulation of DNA endoreduplication

Any process that stops, prevents, or reduces the frequency, rate or extent of DNA endoreduplication.


negative regulation of mRNA catabolic process

Any process that stops, prevents or reduces the frequency, rate or extent of mRNA catabolic process.


negative regulation of purine nucleotide metabolic process

Any process that stops, prevents or reduces the frequency, rate or extent of purine nucleotide metabolic process.


negative regulation of transcription initiation by RNA polymerase II

Any process that decreases the rate, frequency or extent of a process involved in starting transcription from an RNA polymerase II promoter.


telomerase RNA stabilization

Prevention of degradation of telomerase RNA (TERC) molecules.


negative regulation of DNA strand resection involved in replication fork processing

Any process that stops, prevents, or reduces the frequency, rate or extent of DNA strand resection involved in replication fork processing.


negative regulation of single strand break repair

Any process that stops, prevents or reduces the frequency, rate or extent of single strand break repair.


negative regulation of miRNA metabolic process

Any process that stops, prevents or reduces the frequency, rate or extent of miRNA metabolic process.


negative regulation of DNA primase activity

Any process that stops, prevents or reduces the frequency, rate or extent of DNA primase activity.


negative regulation of telomerase RNA reverse transcriptase activity

Any process that stops, prevents or reduces the frequency, rate or extent of telomerase RNA reverse transcriptase activity.


negative regulation of type III site-specific deoxyribonuclease activity

Any process that stops or reduces the rate of type III restriction endodeoxyribonuclease activity.


negative regulation of deadenylation-dependent decapping of nuclear-transcribed mRNA

Any process that stops, prevents, or reduces the frequency, rate or extent of deadenylation-dependent decapping of nuclear-transcribed mRNA.


negative regulation of lncRNA transcription

Any process that decreases the frequency, rate or extent of the synthesis of a lncRNA.


negative regulation of tRNA processing

Any process that stops, prevents, or reduces the frequency, rate or extent of tRNA processing.


negative regulation of nuclear-transcribed mRNA catabolic process, meiosis-specific transcripts

Any process that stops, prevents or reduces the frequency, rate or extent of selective degradation of meiosis-specific nuclear transcribed transcripts during vegetative growth, by a mechanism that requires determinant of selective removal (DSR) sequences in the targeted mRNAs and involves a YTH family protein.


negative regulation of DNA amplification

Any process that stops, prevents or reduces the frequency, rate or extent of DNA amplification.


negative regulation of snoRNA processing

Any process that stops, prevents or reduces the frequency, rate or extent of snoRNA processing.


negative regulation of telomeric loop disassembly

Any process that stops, prevents or reduces the frequency, rate or extent of telomeric loop disassembly.


3'-UTR-mediated mRNA stabilization

An mRNA stabilization process in which one or more RNA-binding proteins associate with the 3'-untranslated region (UTR) of an mRNA.


replication fork arrest at tRNA locus

A process that impedes the progress of the DNA replication fork at natural replication fork pausing sites within the eukaryotic tRNA transcription unit.


negative regulation of snRNA transcription by RNA polymerase II

Any process that stops, prevents or reduces the frequency, rate or extent of snRNA transcription mediated by RNA polymerase II.


negative regulation of mitotic cell cycle DNA replication

Any process that stops, prevents or reduces the frequency, rate or extent of mitotic cell cycle DNA replication.


negative regulation of ncRNA transcription associated with protein coding gene TSS/TES

Any process that stops, prevents or reduces the frequency, rate or extent of ncRNA transcription associated with protein coding gene TSS/TES.


negative regulation of nucleotide biosynthetic process

Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nucleotides.


negative regulation of pyrimidine nucleobase metabolic process

Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving pyrimidine nucleobases.


negative regulation of DNA recombination at telomere

Any process that stops, prevents, or reduces the frequency, rate or extent of genetic recombination within the telomere.


negative regulation of exodeoxyribonuclease activity

Any process that stops, prevents or reduces the frequency, rate or extent of exodeoxyribonuclease activity.


negative regulation of telomere maintenance in response to DNA damage

Any process that stops, prevents or reduces the frequency, rate or extent of telomere maintenance in response to DNA damage.


negative regulation of nuclear-transcribed mRNA poly(A) tail shortening

Any process that decreases the frequency, rate or extent of poly(A) tail shortening of a nuclear-transcribed mRNA. Poly(A) tail shortening is the decrease in length of the poly(A) tail of an mRNA from full length to an oligo(A) length.


inactivation of recombination (HML)

The inactivation of recombination at sequences around a mating type donor locus, with the consequence that the other donor is the only one available for mating type switching; exemplified by the HML locus and surrounding sequences on Chromosome III in Saccharomyces cerevisiae.


negative regulation of transcription by RNA polymerase I

Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase I.


negative regulation of DNA-templated DNA replication

Any process that stops, prevents, or reduces the frequency, rate or extent of DNA-dependent DNA replication.


negative regulation of mRNA modification

Any process that decreases the rate, frequency, or extent of the covalent alteration of one or more nucleotides within an mRNA molecule to produce an mRNA molecule with a sequence that differs from that coded genetically.


negative regulation of type I site-specific deoxyribonuclease activity

Any process that stops or reduces the rate of type I restriction endodeoxyribonuclease activity.


negative regulation of telomerase activity

Any process that stops or reduces the activity of the enzyme telomerase, which catalyzes of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).


negative regulation of telomere capping

Any process that stops, prevents or reduces the frequency, rate or extent of telomere capping.


negative regulation of DNA-templated transcription, elongation

Any process that stops, prevents, or reduces the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides catalyzed by a DNA-dependent RNA polymerase.


negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

Any process that stops, prevents or reduces the frequency, rate or extent of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay.


negative regulation of mating-type specific transcription, DNA-templated

Any mating-type specific process that stops, prevents or reduces the rate of cellular DNA-templated transcription.


negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

Any process that stops, prevents or reduces the frequency, rate or extent of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay.


nitrogen catabolite repression of transcription from RNA polymerase II promoter

A transcription regulation process in which the presence of one nitrogen source leads to a decrease in the frequency, rate, or extent of transcription, from an RNA polymerase II promoter, of specific genes involved in the metabolism of other nitrogen sources.


negative regulation of type II site-specific deoxyribonuclease activity

Any process that stops or reduces the rate of type II restriction endodeoxyribonuclease activity.


negative regulation of RNA splicing

Any process that stops, prevents, or reduces the frequency, rate or extent of RNA splicing.


negative regulation of siRNA processing

Any process that stops, prevents or reduces the frequency, rate or extent of siRNA processing.


negative regulation of endodeoxyribonuclease activity

Any process that stops or reduces the rate of endodeoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid by creating internal breaks.


negative regulation of mitochondrial RNA catabolic process

Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving catabolism in the mitochondrion of RNA transcribed from the mitochondrial genome.


negative regulation of mRNA processing

Any process that stops, prevents, or reduces the frequency, rate or extent of mRNA processing.


negative regulation of DNA-templated DNA replication initiation

Any process that stops, prevents, or reduces the frequency, rate or extent of initiation of DNA-dependent DNA replication.


negative regulation of type IV site-specific deoxyribonuclease activity

Any process that stops or reduces the rate of type IV restriction endodeoxyribonuclease activity.


negative regulation of DNA recombination at centromere

Any process that stops, prevents, or reduces the frequency, rate or extent of genetic recombination at the centromere.


negative regulation of mismatch repair

Any process that stops, prevents, or reduces the frequency, rate or extent of mismatch repair.


negative regulation of DNA demethylation

Any process that stops, prevents or reduces the frequency, rate or extent of DNA demethylation.


replication fork arrest

Any process that stops, prevents, or reduces the frequency, rate or extent of DNA replication by impeding the progress of the DNA replication fork. Replication fork arrest is one of the 'quality control' processes ensuring that DNA-dependent DNA replication occurs correctly. DNA replication fork arrest during DNA-dependent DNA replication is not known to occur outside of cases where a replication error needs to be prevented or corrected.


negative regulation of single stranded viral RNA replication via double stranded DNA intermediate

Any process that stops, prevents, or reduces the frequency, rate or extent of single stranded viral RNA replication via double stranded DNA intermediate.


negative regulation of miRNA transcription

Any process that stops, prevents or reduces the frequency, rate or extent of microRNA (miRNA) gene transcription.


negative regulation of transcription from RNA polymerase II promoter by a nonfermentable carbon source

A transcription regulation process in which the presence of a nonfermentable carbon source leads to a decrease of the frequency, rate, or extent of transcription, from an RNA polymerase II promoter, of specific genes involved in the metabolism of other carbon sources.


negative regulation of snRNA pseudouridine synthesis

Any process that stops, prevents or reduces the frequency, rate or extent of snRNA pseudouridine synthesis.


negative regulation of DNA catabolic process

Any process that stops, prevents or reduces the frequency, rate or extent of DNA catabolic process.


negative regulation of tRNA metabolic process

Any process that stops, prevents or reduces the frequency, rate or extent of tRNA metabolic process.


negative regulation of transcription by transcription factor localization

Any process that stops, prevents, or reduces the frequency, rate or extent of DNA-dependent transcription using a mechanism that involves the localization of a transcription factor.


negative regulation of mRNA polyadenylation

Any process that stops, prevents or reduces the frequency, rate or extent of mRNA polyadenylation.


negative regulation of telomere maintenance via recombination

Any process that stops, prevents, or reduces the frequency, rate or extent of a recombinational process involved in the maintenance of proper telomeric length.


negative regulation of mRNA 3'-end processing

Any process that stops, prevents, or reduces the frequency, rate or extent of mRNA 3'-end processing.


negative regulation of mitochondrial DNA metabolic process

Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrial DNA metabolic process.


negative regulation of nucleoside metabolic process

Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving nucleosides.


negative regulation of transcription by RNA polymerase V

Any process that stops, prevents or reduces the frequency, rate or extent of transcription mediated by RNA polymerase V.


negative regulation of telomeric D-loop disassembly

Any process that stops, prevents or reduces the frequency, rate or extent of telomeric D-loop disassembly.


negative regulation of ribosomal protein gene transcription by RNA polymerase II

Any process that decreases the frequency, rate or extent of the synthesis of RNA from ribosomal protein genes mediated by RNA polymerase II.


negative regulation of mitochondrial mRNA catabolic process

Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrial mRNA catabolic process.


negative regulation of mitochondrial DNA replication

Any process that decreases the rate, frequency or extent of the process in which new strands of DNA are synthesized in the mitochondrion.


negative regulation of nuclear cell cycle DNA replication

Any process that stops, prevents or reduces the frequency, rate or extent of nuclear cell cycle DNA replication.


tRNA stabilization

Prevention of degradation of tRNA molecules.


negative regulation of deoxyribonuclease activity

Any process that stops or reduces the rate of deoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid.


negative regulation of glycolytic process through fructose-6-phosphate

Any process that stops, prevents or reduces the frequency, rate or extent of glycolytic process through fructose-6-phosphate.


negative regulation of mRNA splicing, via spliceosome

Any process that stops, prevents or reduces the rate or extent of mRNA splicing via a spliceosomal mechanism.


negative regulation of rRNA processing

Any process that stops, prevents, or reduces the frequency, rate or extent of rRNA processing.


CRD-mediated mRNA stabilization

An mRNA stabilization process in which one or more RNA-binding proteins associate with a sequence in the open reading frame called the coding region instability determinant (CRD).


negative regulation of DNA replication initiation involved in plasmid copy number maintenance

Any process that decreases the frequency, rate or extent of initiation of plasmid DNA replication that contributes to copy number maintenance.


negative regulation of mitotic DNA replication initiation

Any process that stops, prevents or reduces the frequency, rate or extent of DNA replication initiation involved in mitotic DNA replication.


negative regulation of promoter clearance from RNA polymerase II promoter

A process that stops, prevents or reduces the transition from the initiation to the elongation phases of transcription by RNA polymerase II.


negative regulation of restriction endodeoxyribonuclease activity

Any process that stops or reduces the rate of a restriction endodeoxyribonuclease activity, the catalysis of endonucleolytic cleavage of DNA in a site-specific manner, resulting in double-strand breaks.


negative regulation of miRNA catabolic process

Any process that stops, prevents or reduces the frequency, rate or extent of miRNA catabolic process.


negative regulation of exonuclease activity

Any process that stops, prevents or reduces the frequency, rate or extent of exonuclease activity.


carbon catabolite repression of transcription from RNA polymerase II promoter

A transcription regulation process in which the presence of one carbon source leads to a decrease in the frequency, rate, or extent of transcription, from an RNA polymerase II promoter, of specific genes involved in the metabolism of other carbon sources.


negative regulation of initiation of premeiotic DNA replication

Any process that stops, prevents or reduces the frequency, rate or extent of initiation of premeiotic DNA replication.


negative regulation of DNA-directed DNA polymerase activity

Any process that stops, prevents or reduces the frequency, rate or extent of DNA-directed DNA polymerase activity.


negative regulation of purine nucleotide catabolic process

Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of purine nucleotides.


negative regulation of tRNA catabolic process

Any process that stops, prevents or reduces the frequency, rate or extent of tRNA catabolic process.


replication fork arrest involved in DNA replication termination

A replication fork arrest process that contributes to the termination of DNA replication.


replication fork arrest at rDNA repeats

A process that impedes the progress of the DNA replication fork at natural replication fork pausing sites within the eukaryotic rDNA repeat spacer.


negative regulation of strand invasion

Any process that decreases the rate, frequency or extent of strand invasion. Strand invasion is the process in which the nucleoprotein complex (composed of the broken single-strand DNA and the recombinase) searches and identifies a region of homology in intact duplex DNA. The broken single-strand DNA displaces the like strand and forms Watson-Crick base pairs with its complement, forming a duplex in which each strand is from one of the two recombining DNA molecules.


negative regulation of termination of RNA polymerase II transcription

Any process that stops, prevents or reduces the frequency, rate or extent of termination of RNA polymerase II transcription.


nitrogen catabolite repression of transcription

A transcription regulation process in which the presence of one nitrogen source leads to a decrease in the frequency, rate, or extent of transcription of specific genes involved in the metabolism of other nitrogen sources.


negative regulation of nucleotide catabolic process

Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of nucleotides.


negative regulation of ribonuclease activity

Any process that decreases the rate, frequency, or extent of ribonuclease activity, catalysis of the hydrolysis of phosphodiester bonds in chains of RNA.


negative regulation of antisense RNA transcription

Any process that decreases the frequency, rate or extent of the synthesis of antisense RNA, an RNA molecule complementary in sequence to another RNA or DNA molecule, which, by binding the latter, acts to inhibit its function and/or completion of synthesis, on a template of DNA.


negative regulation of double-strand break repair via break-induced replication

Any process that stops, prevents or reduces the frequency, rate or extent of double-strand break repair via break-induced replication.


negative regulation of DNA biosynthetic process

Any process that stops, prevents or reduces the frequency, rate or extent of DNA biosynthetic process.


negative regulation of termination of RNA polymerase II transcription, poly(A)-coupled

Any process that stops, prevents or reduces the frequency, rate or extent of termination of RNA polymerase II transcription, poly(A)-coupled.


negative regulation of base-excision repair

Any process that stops, prevents or reduces the frequency, rate or extent of base-excision repair.


negative regulation of DNA-templated transcription initiation

Any process that stops, prevents, or reduces the frequency, rate or extent of DNA-templated transcription initiation.


negative regulation of nucleotide metabolic process

Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving nucleotides.


negative regulation of DNA methylation

Any process that stops, prevents or reduces the frequency, rate or extent of DNA methylation.


negative regulation of RNA polymerase III activity

Any process that stops, prevents or reduces the frequency, rate or extent of RNA polymerase III activity.


negative regulation of ribosomal protein gene transcription from RNA polymerase II promoter in response to chemical stimulus

Any process that decreases the frequency, rate or extent of the synthesis of RNA from ribosomal protein genes by RNA polymerase II, originating at an RNA polymerase II promoter, as a result of a chemical stimulus.


carbon catabolite repression of transcription from RNA polymerase II promoter by galactose

Any process involving galactose that stops, prevents or reduces the rate of transcription from an RNA polymerase II promoter.


negative regulation of purine nucleobase metabolic process

Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving purine nucleobases.


negative regulation of DNA replication

Any process that stops, prevents, or reduces the frequency, rate or extent of DNA replication.


transcription antitermination

A positive regulation of gene expression mechanism that allows RNA polymerase to continue transcription beyond a termination site, thus allowing expression of downstream genes under specific conditions.


carbon catabolite repression of transcription

A transcription regulation process in which the presence of one carbon source leads to a decrease in the frequency, rate, or extent of transcription of specific genes involved in the metabolism of other carbon sources. Carbon catabolite repression is a mechanism of genetic regulation which the accumulation of catabolites of one substance in the cell represses the formation of enzymes that contribute to the catabolism of other substances.


detection of salicylic acid stimulus

The series of events in which a salicylic acid stimulus is received by a cell and converted into a molecular signal.


response to salicylic acid

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a salicylic acid stimulus.


cellular response to salicylic acid stimulus

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a salicylic acid stimulus.


response to herbicide

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a herbicide stimulus. Herbicides are chemicals used to kill or control the growth of plants.


osmosensory signaling pathway via Sho1 osmosensor

biolink:Pathway biolink:BiologicalProcess biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:OntologyClass biolink:Occurrent biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

The series of molecular signals generated in response to osmotic change, as mediated through a Sho1 osmosensor system.


osmosensory signaling pathway

The series of molecular signals initiated in response to osmotic change.


osmosensory signaling via phosphorelay pathway

The series of molecular signals generated in response to osmotic change, as mediated through a phosphorelay system. In S.cerevisiae, the osmosensor is the histidine kinase Sln1.


medulla oblongata formation

The process that gives rise to the medulla oblongata. This process pertains to the initial formation of a structure from unspecified parts. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate.


negative regulation of response to benzene

Any process that stops, prevents or reduces the frequency, rate or extent of response to benzene.


regulation of response to benzene

Any process that modulates the frequency, rate or extent of response to benzene.


positive regulation of response to benzene

Any process that activates or increases the frequency, rate or extent of response to benzene.


calmodulin-activated 3',5'-cyclic-AMP phosphodiesterase activity

Catalysis of the reactions: nucleoside 3',5'-cyclic AMP + H2O = AMP + H+; this activity is activated by binding to calcium-bound calmodulin.


heparan sulfate proteoglycan catabolic process

The chemical reactions and pathways resulting in the breakdown of proteoglycan containing heparan sulfate, any member of a group of glycosaminoglycans that have repeat units consisting of alternating alpha-(1->4) linked hexuronic acid and glucosamine residues, the former being a mixture of sulfated and nonsulfated D-glucuronic and L-iduronic acids, and the latter being either sulfated or acetylated on its amino group as well as sulfated on one of its hydroxyl groups.


chitobiose catabolic process

The chemical reactions and pathways resulting in the breakdown of any chitobiose, a family of compounds derived from chitin and based on the structure of D-glucosaminyl-(1->4)-D-glucosamine.


chitin catabolic process

The chemical reactions and pathways resulting in the breakdown of chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues.


hyaluronan catabolic process

The chemical reactions and pathways resulting in the breakdown of hyaluronan, the naturally occurring anionic form of hyaluronic acid, any member of a group of glycosaminoglycans, the repeat units of which consist of beta-1,4 linked D-glucuronyl-beta-(1,3)-N-acetyl-D-glucosamine.


N-acetylglucosamine catabolic process

The chemical reactions and pathways resulting in the breakdown of N-acetylglucosamine. The D isomer is a common structural unit of glycoproteins in plants, bacteria and animals; it is often the terminal sugar of an oligosaccharide group of a glycoprotein.


peptidoglycan catabolic process

The chemical reactions and pathways resulting in the breakdown of peptidoglycans, any of a class of glycoconjugates found in bacterial cell walls.


glycosylceramide catabolic process

The chemical reactions and pathways resulting in the breakdown of glycosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of a monosaccharide (or derivative) by a ceramide group.


glycopeptide catabolic process

The chemical reactions and pathways resulting in the breakdown of glycopeptides, a compound in which carbohydrate is covalently attached to an oligopeptide composed of residues of L and/or D-amino acids. The term usually denotes a product of proteolytic degradation of a glycoprotein but includes glycated peptide.


chondroitin sulfate catabolic process

The chemical reactions and pathways resulting in the breakdown of chondroitin sulfate, any member of a group of 10-60 kDa glycosaminoglycans, widely distributed in cartilage and other mammalian connective tissues, the repeat units of which consist of beta-(1,4)-linked D-glucuronyl beta-(1,3)-N-acetyl-D-galactosamine sulfate.


butirosin catabolic process

The chemical reactions and pathways resulting in the breakdown of butirosin.


anthocyanin-containing compound catabolic process

The chemical reactions and pathways resulting in the breakdown of anthocyanins, any member of a group of intensely colored soluble glycosides of anthocyanidins.


proteoglycan catabolic process

The chemical reactions and pathways resulting in the breakdown of proteoglycans, any glycoprotein in which the carbohydrate units are glycosaminoglycans.


amino disaccharide catabolic process

The chemical reactions and pathways resulting in the breakdown of any amino disaccharide, a disaccharide having one or more substituted or unsubstituted amino groups in place of hydroxy groups at unspecified positions.


gentamycin catabolic process

The chemical reactions and pathways resulting in the breakdown of gentamycin.


keratan sulfate catabolic process

The chemical reactions and pathways resulting in the breakdown of keratan sulfate, a glycosaminoglycan with repeat units consisting of beta-1,4-linked D-galactopyranosyl-beta-(1,4)-N-acetyl-D-glucosamine 6-sulfate and with variable amounts of fucose, sialic acid and mannose units; keratan sulfate chains are covalently linked by a glycosidic attachment through the trisaccharide galactosyl-galactosyl-xylose to peptidyl-threonine or serine residues.


paromomycin catabolic process

The chemical reactions and pathways resulting in the breakdown of paromomycin.


glycosaminoglycan catabolic process

The chemical reactions and pathways resulting in the breakdown of glycosaminoglycans, any one of a group of polysaccharides that contain amino sugars.


deoxyribose phosphate catabolic process

The chemical reactions and pathways resulting in the breakdown of deoxyribose phosphate, the phosphorylated sugar 2-deoxy-erythro-pentose.


The chemical reactions and pathways resulting in the breakdown of sophorosyloxydocosanoate, 13-sophorosyloxydocosanoate 6',6''-diacetate.


2-deoxyribose 1-phosphate catabolic process

The chemical reactions and pathways resulting in the breakdown of deoxyribose 1-phosphate, the phosphorylated sugar 1-phospho-2-deoxyribose.


glucosamine-containing compound catabolic process

The chemical reactions and pathways resulting in the breakdown of glucosamine-containing compounds (glucosamines).


O-sialoglycoprotein catabolic process

The chemical reactions and pathways resulting in the breakdown of O-sialoglycoproteins, glycoproteins which contain sialic acid as one of their carbohydrates. They are often found on or in the cell or tissue membranes and participate in a variety of biological activities.


cuticle chitin catabolic process

The chemical reactions and pathways resulting in the breakdown of cuticle chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues, found in cuticles.


galactosylceramide catabolic process

The chemical reactions and pathways resulting in the breakdown of galactosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of galactose by a ceramide group.


The chemical reactions and pathways resulting in the breakdown of poly-N-acetyllactosamine, a carbohydrate composed of N-acetyllactosamine repeats (Gal-beta-1,4-GlcNAc-beta-1,3)n.


amylopectin catabolic process

The chemical reactions and pathways resulting in the breakdown of an amylopectin.


glucuronoside catabolic process

The chemical reactions and pathways resulting in the breakdown of glucuronosides, compound composed of a hydroxy compound linked to a glucuronate residue.


galactosaminoglycan catabolic process

The chemical reactions and pathways resulting in the breakdown of galactosaminoglycans, any of a group of polysaccharides that contain amino sugars derived from the galactose.


cell wall chitin catabolic process

The chemical reactions and pathways resulting in the breakdown of cell wall chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues, found in the walls of cells.


ubiquitin-dependent glycoprotein ERAD pathway

An ERAD pathway whereby endoplasmic reticulum (ER)-resident glycoproteins are targeted for degradation. Includes differential processing of the glycoprotein sugar chains, retrotranslocation to the cytosol and degradation by the ubiquitin-proteasome pathway. A glycoprotein is a compound in which a carbohydrate component is covalently bound to a protein component.


aminoglycan catabolic process

The chemical reactions and pathways resulting in the breakdown of aminoglycans, any polymer containing amino groups that consists of more than about 10 monosaccharide residues joined to each other by glycosidic linkages.


lincomycin catabolic process

The chemical reactions and pathways resulting in the breakdown of lincomycin.


ganglioside catabolic process

The chemical reactions and pathways resulting in the breakdown of ganglioside, a ceramide oligosaccharide carrying, in addition to other sugar residues, one or more sialic residues.


neomycin catabolic process

The chemical reactions and pathways resulting in the breakdown of neomycin.


S-glycoside catabolic process

The chemical reactions and pathways resulting in the breakdown of S-glycosides, any compound in which a glycosyl group has been substituted into a thiol group.


D-tagatose 6-phosphate catabolic process

The chemical reactions and pathways resulting in the breakdown of a D-tagatose 6-phosphate.


ascospore wall chitin catabolic process

The chemical reactions and pathways resulting in the breakdown of ascospore wall chitin, a linear polysaccharide consisting of P-1,4-linked N-acetyl-D-glucosamine residues, found in the walls of ascospores.


lipoteichoic acid catabolic process

The chemical reactions and pathways resulting in the breakdown of lipoteichoic acid, which is a major component of the cell wall of gram-positive bacteria and typically consists of a chain of glycerol-phosphate repeating units linked to a glycolipid anchor.


lipopolysaccharide catabolic process

The chemical reactions and pathways resulting in the breakdown of lipopolysaccharides, any of a group of related, structurally complex components of the outer membrane of Gram-negative bacteria.


kanamycin catabolic process

The chemical reactions and pathways resulting in the breakdown of kanamycin.


diacetylchitobiose catabolic process

The chemical reactions and pathways resulting in the breakdown of diacetylchitobiose into simpler products.


diacetylchitobiose catabolic process to glucosamine and acetate

The pathway resulting in the breakdown of diacetylchitobiose into simpler products, including glucosamine and glucosamine. The catabolism proceeds by the deacetylation of diacetylchitobiose, producing acetate and GlcN-GlcNAc; the latter is cleaved to produce glucosamine (GlcN) and N-acetylglucosamine (GlcNAc). The N-acetylglucosamine (GlcNAc) is then deacetylated to produce glucosamine (GlcN) and acetate.


aminoglycoside antibiotic catabolic process

The chemical reactions and pathways resulting in the breakdown of an aminoglycoside antibiotic, any member of a group of broad spectrum antibiotics, of similar toxicity and pharmacology, that contain an aminodeoxysugar, an amino- or guanidino-substituted inositol ring, and one or more residues of other sugars. The group includes streptomycin, neomycin, framycetin, kanamycin, paromomycin, and gentamicin.


ergosteryl 3-beta-D-glucoside catabolic process

The chemical reactions and pathways resulting in the breakdown of ergosteryl 3-beta-D-glucoside.


N-acetylmannosamine catabolic process

The chemical reactions and pathways resulting in the breakdown of N-acetylmannosamine, the acetylated derivative of mannosamine, 2-amino-2-deoxymannose.


mannosamine catabolic process

The chemical reactions and pathways resulting in the breakdown of mannosomine, 2-amino-2-deoxymannose; the D-isomer is a constituent of neuraminic acids as well as mucolipids and mucoproteins.


mannoprotein catabolic process

The chemical reactions and pathways resulting in the breakdown of a mannoprotein, a protein that contains covalently bound mannose residues.


teichoic acid catabolic process

The chemical reactions and pathways resulting in the breakdown of teichoic acid, which is a major component of the cell wall of Gram-positive bacteria and typically consists of a polymer of glycerol-phosphate or ribitol-phosphate to which are attached glycosyl and D-alanyl ester residues.


galactolipid catabolic process

The chemical reactions and pathways resulting in the breakdown of galactolipids, any glycolipid containing one of more residues of galactose and/or N-acetylgalactosamine.


glycoprotein catabolic process

The chemical reactions and pathways resulting in the breakdown of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide.


heparin catabolic process

The chemical reactions and pathways resulting in the breakdown of heparin, any member of a group of glycosaminoglycans of average Mr (6000-20000), consisting predominantly of alternating alpha-(1->4)-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues.


glycoside catabolic process

The chemical reactions and pathways resulting in the breakdown of glycosides, compounds in which a glycosyl group is substituted into a hydroxyl, thiol or selenol group in another compound.


glycosphingolipid catabolic process

The chemical reactions and pathways resulting in the breakdown of glycosphingolipid, a compound with residues of sphingoid and at least one monosaccharide.


lipooligosaccharide catabolic process

The chemical reactions and pathways resulting in the breakdown of lipooligosaccharide.


saponin catabolic process

The chemical reactions and pathways resulting in the breakdown of saponins, glycosides of plants in which the aglycan (sapogenin) group is a terpene or steroid and the sugar group is a glucose, a galactose, a pentose, a methylpentose or an oligosaccharide. Saponins are powerful surfactant agents and membrane active; they are, hence, toxic to animals on injection.


glucosylceramide catabolic process

The chemical reactions and pathways resulting in the breakdown of glucosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of glucose by a ceramide group.


glycolipid catabolic process

The chemical reactions and pathways resulting in the breakdown of glycolipid, a class of 1,2-di-O-acylglycerols joined at oxygen 3 by a glycosidic linkage to a carbohydrate part (usually a mono-, di- or tri-saccharide).


beta-glucoside catabolic process

The chemical reactions and pathways resulting in the breakdown of beta-glucoside.


zeaxanthin bis(beta-D-glucoside) catabolic process

The chemical reactions and pathways resulting in the breakdown of zeaxanthin bis(beta-D-glucoside).


elastin catabolic process

The chemical reactions and pathways resulting in the breakdown of elastin. Elastin is a glycoprotein which is randomly coiled and crosslinked to form elastic fibers that are found in connective tissue.


fructosamine catabolic process

The chemical reactions and pathways resulting in the breakdown of fructosamine, a fructose molecule containing an amino group in place of a hydroxyl group.


leaf papilla

A plant cell papilla that is part of a leaf papilla cell.


U12-type post-mRNA release spliceosomal complex

A spliceosomal complex that is formed following the release of the spliced product from the post-spliceosomal complex and contains the excised intron and the U12, U5 and U6atac snRNPs.


U12-type prespliceosome

A spliceosomal complex that is formed by the cooperative binding of the heterodimeric U11/U12 snRNP to the 5' splice site and the branch point sequence. The U12-type prespliceosome includes many proteins in addition to those found in the U11/U12 heterodimeric snRNPs. Commitment to a given pair of 5' and 3' splice sites occurs at the time of prespliceosome formation.


supraspliceosomal complex

Multicomponent complex of RNA and proteins that is composed of four active spliceosomes, termed native spliceosomes, connected to each other by the pre-mRNA. The supraspliceosome is the nuclear machine where the pre-mRNA processing takes place, like the 5'-end capping, 3'-end cleavage, splicing and editing.


U12-type precatalytic spliceosome

A spliceosomal complex that is formed by the recruitment of the preassembled U4atac/U6atac.U5 tri-snRNP to the U12-type prespliceosome. Although all 5 snRNPs are present, the precatalytic spliceosome is catalytically inactive. The precatalytic spliceosome includes many proteins in addition to those found in the U11, U12 and U4atac/U6atac.U5 snRNPs.


U12-type post-spliceosomal complex

A spliceosomal complex that is formed following the second splicing event and contains the spliced product, the excised intron, and three snRNPs, U5, U12 and U6atac.


U2-type post-spliceosomal complex

A spliceosomal complex that is formed following the second splicing event and contains the spliced product, the excised intron, and three snRNPs, U5, U2 and U6.


U12-type catalytic step 2 spliceosome

A spliceosomal complex that contains the U12, U5 and U6atac snRNPs bound to a splicing intermediate in which the first catalytic cleavage of the 5' splice site has occurred. The precise subunit composition differs significantly from that of the catalytic step 1, or activated, spliceosome, and includes many proteins in addition to those found in the U12, U5 and U6atac snRNPs.


post-spliceosomal complex

A spliceosomal complex that is formed following the second splicing event and contains the spliced product, the excised intron, and three snRNPs, including U5.


prespliceosome

A spliceosomal complex that is formed by association of the 5' splice site and the branch point sequence with specific snRNPs. The prespliceosome includes many proteins in addition to those found in the bound snRNPs. Commitment to a given pair of 5' and 3' splice sites occurs at the time of prespliceosome formation. Prespliceosome complexes are not active for splicing, but are instead an early step in the assembly of a spliceosomal complex.


commitment complex

A spliceosomal complex that is formed by association of the U1 snRNP with the 5' splice site of an unspliced intron in an RNA transcript.


U2-type precatalytic spliceosome

A spliceosomal complex that is formed by the recruitment of the preassembled U4/U6.U5 tri-snRNP to the prespliceosome. Although all 5 snRNPs are present, the precatalytic spliceosome is catalytically inactive. The precatalytic spliceosome includes many proteins in addition to those found in the U1, U2 and U4/U6.U5 snRNPs.


catalytic step 1 spliceosome

A spliceosomal complex that is formed by the displacement of the two snRNPs from the precatalytic spliceosome; three snRNPs including U5 remain associated with the mRNA. This complex, sometimes called the activated spliceosome, is the catalytically active form of the spliceosome, and includes many proteins in addition to those found in the associated snRNPs.


trans spliceosomal complex

A spliceosomal complex that forms during the addition of a specific spliced leader (SL) sequence to the 5'-end of a messenger RNA primary transcript, a process which occurs in a number of eukaryotic organisms, including trypanosomatid protozoans, euglenoids, nematodes, trematodes, and chordates.


U2-type catalytic step 1 spliceosome

A spliceosomal complex that is formed by the displacement of the U1 and U4 snRNPs from the precatalytic spliceosome; the U2, U5 and U6 snRNPs remain associated with the mRNA. This complex, sometimes called the activated spliceosome, is the catalytically active form of the spliceosome, and includes many proteins in addition to those found in the U2, and U5 and U6 snRNPs.


U12-type catalytic step 1 spliceosome

A spliceosomal complex that is formed by the displacement of the U11 and U4atac snRNPs from the precatalytic spliceosome; the U12, U5 and U6atac snRNPs remain associated with the mRNA. This complex, sometimes called the activated spliceosome, is the catalytically active form of the spliceosome, and includes many proteins in addition to those found in the U12, and U5 and U6atac snRNPs.


U2-type post-mRNA release spliceosomal complex

A spliceosomal complex that is formed following the release of the spliced product from the post-spliceosomal complex and contains the excised intron and the U2, U5 and U6 snRNPs.


U2-type catalytic step 2 spliceosome

A spliceosomal complex that contains the U2, U5 and U6 snRNPs bound to a splicing intermediate in which the first catalytic cleavage of the 5' splice site has occurred. The precise subunit composition differs significantly from that of the catalytic step 1, or activated, spliceosome, and includes many proteins in addition to those found in the U2, U5 and U6 snRNPs.


negative regulation of establishment of endothelial barrier

Any process that stops, prevents or reduces the frequency, rate or extent of establishment of endothelial barrier.


regulation of aplanospore formation

Any process that modulates the frequency, rate or extent of aplanospore formation, a process in which a nonmotile, asexual spore is formed within a cell in certain algae and fungi (commonly in the Phycomycetes), the wall of aplanospore is distinct from that of the parent cell.


positive regulation of aplanospore formation

Any process that activates, maintains or increases the frequency, rate or extent of aplanospore formation, a process in which a nonmotile, asexual spore is formed within a cell in certain algae and fungi (commonly in the Phycomycetes), the wall of aplanospore is distinct from that of the parent cell.


heme C biosynthetic process

The chemical reactions and pathways resulting in the formation of heme c, a derivative of heme found in cytochromes c, b4, and f.


ATP-dependent H2AZ histone chaperone activity

A histone chaperone that mediates the exchange of histone H2A-H2B dimer and histone H2AZ-H2B dimers in a nucleosome, driven by ATP hydrolysis. Some chaperones insert H2AZ-H2B dimers and remove H2A-H2B, while others do the opposite.


maltose transporting porin activity

Enables the transfer of maltose from one side of a membrane to the other. Maltose is the disaccharide 4-O-alpha-D-glucopyranosyl-D-glucopyranose, an intermediate in the enzymatic breakdown of glycogen and starch. This transporter is a porin so enables the energy independent passage of substances, sized less than 1000 Da, across a membrane. The transmembrane portions of porins consist exclusively of beta-strands which form a beta-barrel. They are found in the outer membranes of Gram-negative bacteria, mitochondria, plastids and possibly acid-fast Gram-positive bacteria.


gluconeogenesis

The formation of glucose from noncarbohydrate precursors, such as pyruvate, amino acids and glycerol.


insulin-like growth factor binary complex

A complex of two proteins, which in animals is 50kDa and consists of the insulin-like growth factor (IGF) and one of the insulin-like growth factor binding protein-1 (IGFBP-1), -2 (IGFBP-2), -4 (IGFBP-4) and -6 (IGFBP-6). The complex plays a role in growth and development.


regulation of telomeric loop disassembly

Any process that modulates the frequency, rate or extent of telomeric loop disassembly.


positive regulation of telomeric D-loop disassembly

Any process that activates or increases the frequency, rate or extent of telomeric D-loop disassembly.


positive regulation of telomeric loop disassembly

Any process that activates or increases the frequency, rate or extent of telomeric loop disassembly.


regulation of telomeric D-loop disassembly

Any process that modulates the frequency, rate or extent of telomeric D-loop disassembly.


positive regulation of receptor signaling pathway via STAT

Any process that activates or increases the frequency, rate or extent of receptor signaling pathway via STAT.


positive regulation of pheromone response MAPK cascade

Any process that activates or increases the frequency, rate or extent of a pheromone response MAPK cascade.


positive regulation of ERK5 cascade

Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the ERK5 cascade.


positive regulation of cell wall integrity MAPK cascade

Any process that activates or increases the frequency, rate or extent of MAPK cascade involved in cell wall organization or biogenesis.


positive regulation of p38MAPK cascade

Any process that activates or increases the frequency, rate or extent of p38MAPK cascade.


positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway

The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands resulting in an increase in the rate or frequency of a MAPKKK cascade.


tRNA adenosine(64)-2'-O-ribosylphosphate transferase activity

Catalysis of the transfer of a phosphoribosyl group from 5'-phosphoribosyl-1'-pyrophosphate to position 64 of initiator tRNA.


female somatic sex determination

The determination of sex and sexual phenotypes in a female organism's soma.


proton-transporting V-type ATPase, V0 domain

A protein complex that forms part of a proton-transporting V-type ATPase and mediates proton transport across a membrane. The V0 complex consists of at least four different subunits (a,c,d and e); six or more c subunits form a proton-binding rotor ring.


plasma membrane proton-transporting V-type ATPase, V0 domain

The V0 domain of a proton-transporting V-type ATPase found in the plasma membrane.


vacuolar proton-transporting V-type ATPase, V0 domain

The V0 domain of a proton-transporting V-type ATPase found in the vacuolar membrane.


lysosomal proton-transporting V-type ATPase, V0 domain

The V0 domain of a proton-transporting V-type ATPase found in the lysosomal membrane.


chorionic trophoblast cell proliferation

The multiplication or reproduction of chorionic trophoblast cells, resulting in the expansion of their population.


negative regulation of T-helper 2 cell differentiation

Any process that stops, prevents, or reduces the frequency, rate or extent of T-helper 2 cell differentiation.


mycothiol biosynthetic process

The chemical reactions and pathways resulting in the formation of mycothiol, which consists of N-acetyl-L-cysteine linked to a pseudodisaccharide, D-glucosamine and myo-inositol. Mycothiol is produced in actinomycetes like mycobacteria and serves similar functions to glutathione.


cellular response to ethanol

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ethanol stimulus.


response to ethanol

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ethanol stimulus.


deoxyuridine biosynthetic process

The chemical reactions and pathways resulting in the formation of deoxyuridine, 2-deoxyribosyluracil, one of the four major nucleosides of DNA.


1,1,2-trichloroethene reductive dehalogenase activity

Catalysis of the reaction: trichloroethene + 2 H+ + 2 e- = HCl + 1,2-dichloroethene.


Catalysis of the reaction: L-proline + NAD(P)+ = 1-pyrroline-2-carboxylate + NAD(P)H + H+.


cellular response to external biotic stimulus

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external biotic stimulus, an external stimulus caused by, or produced by living things.


lateral motor column neuron differentiation

The process in which differentiating motor neurons in the neural tube acquire the specialized structural and/or functional features of lateral motor column neurons. Lateral motor column neurons are generated only on limb levels and send axons into the limb mesenchyme. Differentiation includes the processes involved in commitment of a cell to a specific fate.


reactive gliosis

A neuroinflammatory response, occurring over several days, during which glial cells undergo nonspecific reactive changes in response to damage to the central nervous system (CNS); typically involves the proliferation or hypertrophy of different types of glial cells.


Catalysis of the reaction: isorhamnetin + S-adenosyl-L-methionine = 3,3'-dimethylquercetin + S-adenosyl-L-homocysteine.


glycine dehydrogenase (decarboxylating) activity

Catalysis of the reaction: glycine + lipoylprotein = S-aminomethyldihydrolipoylprotein + CO2.


oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor

Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and reduces a disulfide group.


cardioblast migration to the midline involved in heart rudiment formation

The orderly movement of a cardioblast toward the midline that contributes to the initial appearance of the heart rudiment.


negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis

Any process that stops, prevents, or reduces the frequency, rate or extent of planar cell polarity pathway involved in cardiac right atrium morphogenesis.


negative regulation of planar cell polarity pathway involved in heart morphogenesis

Any process that stops, prevents, or reduces the frequency, rate or extent of planar cell polarity pathway involved in heart morphogenesis.


negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis

Any process that stops, prevents, or reduces the frequency, rate or extent of planar cell polarity pathway involved in outflow tract morphogenesis.


negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis

Any process that stops, prevents, or reduces the frequency, rate or extent of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis.


negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis

Any process that stops, prevents, or reduces the frequency, rate or extent of planar cell polarity pathway involved in ventricular septum morphogenesis.


negative regulation of planar cell polarity pathway involved in pericardium morphogenesis

Any process that stops, prevents, or reduces the frequency, rate or extent of planar cell polarity pathway involved in pericardium morphogenesis.


synaptic vesicle tethering involved in synaptic vesicle exocytosis

The initial, indirect interaction between a synaptic vesicle membrane and a the preseynaptic membrane active zone. This interaction is mediated by tethering factors (or complexes), which interact with both membranes. This process is distinct from and prior to synaptic vesicle priming and fusion.


P2Y5 nucleotide receptor binding

Binding to a P2Y5 nucleotide receptor.


bacterial-type flagellum rotor complex

The rotor complex of the bacterial-type flagellum consists of a membrane-anchored ring and the motor switch complex, which participates in the conversion of proton/Na+ energy into the mechanical work of rotation and controls the direction of flagellar rotation.


formamide biosynthetic process

The chemical reactions and pathways resulting in the formation of formamide, the simplest amide, HCONH2, derived from formic acid.


D-tagatose 6-phosphate metabolic process

The chemical reactions and pathways involving a D-tagatose 6-phosphate.


peptidyl-(Z)-dehydrobutyrine biosynthetic process from peptidyl-threonine

The formation of (Z)-dehydrobutyrine by the dehydration of peptidyl-threonine.


lateral mesoderm morphogenesis

The process in which the anatomical structures of the lateral mesoderm are generated and organized.


nephrogenic mesenchyme development

The biological process whose specific outcome is the progression of a nephrogenic mesenchyme from an initial condition to its mature state. This process begins with the formation of nephrogenic mesenchyme and ends with the mature structure. Nephrogenic mesenchyme is the tissue made up of loosely connected mesenchymal cells in the nephron.


mitochondrial tricarboxylic acid cycle enzyme complex

Any of the heteromeric enzymes, located in the mitochondrion, that act in the tricarboxylic acid (TCA) cycle.


succinate-CoA ligase complex (GDP-forming)

A heterodimeric enzyme complex, usually composed of an alpha and beta chain. Functions in the TCA cycle, hydrolyzing succinyl-CoA into succinate and CoA, thereby forming GTP.


mitochondrial alpha-ketoglutarate dehydrogenase complex

Mitochondrial complex that possesses alpha-ketoglutarate dehydrogenase activity.


mitochondrial isocitrate dehydrogenase complex (NAD+)

Mitochondrial complex that possesses isocitrate dehydrogenase (NAD+) activity.


mitochondrial oxoglutarate dehydrogenase complex

A complex of multiple copies of three enzymatic components: oxoglutarate dehydrogenase (lipoamide) (E1), dihydrolipoamide S-succinyltransferase (E2) and dihydrolipoamide dehydrogenase (E3); catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and carbon dioxide (CO2) within the mitochondrial matrix. An example of this complex is found in Mus musculus.


Catalysis of the reaction: 4alpha-hydroxymethyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(241)-en-3beta-ol + NADH + O2 + H+ = 4alpha-formyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(241)-en-3beta-ol + NAD + 2 H2O.


regulation of nucleotide biosynthetic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nucleotides.


regulation of reactive oxygen species metabolic process

Any process that modulates the frequency, rate or extent of reactive oxygen species metabolic process.


regulation of interleukin-1 production

Any process that modulates the frequency, rate, or extent of interleukin-1 production.


regulation of chemokine production

Any process that modulates the frequency, rate, or extent of chemokine production.


regulation of heterochromatin formation

Any process that modulates the frequency, rate, extent or location of heterochromatin formation.


positive regulation of mating-type specific transcription, DNA-templated

Any mating-type specific process that activates or increases the rate of cellular DNA-templated transcription.


negative regulation of gene expression via CpG island methylation

An epigenetic gene regulation mechanism that negatively regulates gene expression by methylation of cytosine residues in chromosomal CpG islands. CpG islands are genomic regions that contain a high frequency of the CG dinucleotide and are often associated with the transcription start site of genes.


regulation of inositol phosphate biosynthetic process

Any process that modulates the rate, frequency or extent of inositol phosphate biosynthesis. Inositol phosphate biosynthetic processes are the chemical reactions and pathways resulting in the formation of an inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with one or more phosphate groups attached.


negative regulation of triglyceride metabolic process

Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving triglyceride, any triester of glycerol.


positive regulation of double-strand break repair via nonhomologous end joining

Any process that activates or increases the frequency, rate or extent of double-strand break repair via nonhomologous end joining.


regulation of nuclear-transcribed mRNA catabolic process, meiosis-specific transcripts

Any process that modulates the rate, frequency, or extent of selective degradation of meiosis-specific nuclear transcribed transcripts during vegetative growth, by a mechanism that requires determinant of selective removal (DSR) sequences in the targeted mRNAs and involves a YTH family protein.


positive regulation of inositol phosphate biosynthetic process

Any process that increases the rate, frequency or extent of inositol phosphate biosynthesis. Inositol phosphate biosynthetic processes are the chemical reactions and pathways resulting in the formation of an inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with one or more phosphate groups attached.


regulation of transcription initiation by RNA polymerase II

Any process that modulates the rate, frequency or extent of a process involved in starting transcription from an RNA polymerase II promoter.


regulation of guanylate cyclase activity

Any process that modulates the frequency, rate or extent of guanylate cyclase activity.


regulation of phosphatidylglycerol biosynthetic process

Any process that modulates the frequency, rate or extent of phosphatidylglycerol biosynthetic process.


siRNA-mediated gene silencing by mRNA destabilization

An siRNA-mediated post-transcriptional gene silencing pathway in which small interfering RNAs (siRNAs) direct the cleavage of target mRNAs. Once incorporated into a RNA-induced silencing complex (RISC), an siRNA will typically direct cleavage by base pairing with perfect or near-perfect complementarity to the target mRNA.


regulation of ncRNA transcription

Any process that modulates the frequency, rate or extent of transcription of a non-protein coding gene from a DNA-template.


regulation of tatiopterin biosynthetic process

Any process that modulates the frequency, rate or extent of tatiopterin biosynthetic process.


regulation of nonadec-1-ene metabolic process

Any process that modulates the frequency, rate or extent of nonadec-1-ene metabolic process.


regulation of ethylene biosynthetic process

Any process that modulates the frequency, rate, or extent of an ethylene biosynthetic process.


maternal-to-zygotic transition of gene expression

Any process that modulates the frequency, rate or extent of gene expression by which developmental control passes from the maternal genome to the zygotic genome.


negative regulation of methyl-branched fatty acid biosynthetic process

Any process that stops, prevents or reduces the frequency, rate or extent of methyl-branched fatty acid biosynthetic process.


regulation of reticulophagy

Any process that modulates the frequency, rate or extent of reticulophagy.


regulation of mitotic cell cycle DNA replication

Any process that modulates the frequency, rate or extent of mitotic cell cycle DNA replication.


negative regulation of tetrapyrrole metabolic process

Any process that stops, prevents or reduces the frequency, rate or extent of tetrapyrrole metabolic process.


regulation of antibacterial peptide secretion

Any process that modulates the frequency, rate, or extent of antibacterial peptide secretion.


regulation of cutin biosynthetic process

Any process that modulates the frequency, rate or extent of cutin biosynthetic process.


positive regulation of purine nucleotide catabolic process

Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of purine nucleotides.


regulation of antifungal peptide secretion

Any process that modulates the frequency, rate, or extent of antifungal peptide secretion.


negative regulation of toluene metabolic process

Any process that stops, prevents or reduces the frequency, rate or extent of toluene metabolic process.


regulation of transcription from RNA polymerase II promoter by glucose

Any process involving glucose that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter.


negative regulation of interleukin-1 alpha production

Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-1 alpha production.


negative regulation of carotenoid biosynthetic process

Any process that stops, prevents or reduces the frequency, rate or extent of carotenoid biosynthetic process.


negative regulation of transforming growth factor beta1 production

Any process that stops, prevents, or reduces the frequency, rate, or extent of production of transforming growth factor-beta1.


regulation of transforming growth factor beta3 production

Any process that modulates the frequency, rate, or extent of production of transforming growth factor-beta3.


positive regulation of vitamin E biosynthetic process

Any process that activates or increases the frequency, rate or extent of vitamin E biosynthetic process.


negative regulation of macrophage colony-stimulating factor production

Any process that stops, prevents or reduces the frequency, rate or extent of macrophage colony-stimulating factor production.


regulation of hydrogen peroxide metabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving hydrogen peroxide.


regulation of cell wall (1->3)-beta-D-glucan biosynthetic process

Any process that modulates the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds, found in the walls of cells.


symbiont-mediated suppression of host gene expression

A process in which a symbiont inhibits or disrupts expression of genes in its host. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Some protein processing events may be included when they are required to form an active form of a product from an inactive precursor form. The host is defined as the larger of the organisms involved in a symbiotic interaction.


programmed DNA elimination by elimination of internal DNA segments

A programmed DNA elimination mechanism in which specific sequences, namely, internal eliminated sequences (IES) and breakage eliminated sequences (BES) are removed from the genome. This process is known to occur in ciliates.


negative regulation of interleukin-37 production

Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-37 production.


transitive RNA interference

An RNA interference where the silencing signal spreads along the target mRNA in a 5' or 3' direction, outside of the initial target sequence.


epigenetic programming in the central cell

The establishment of epigenetic modifications (imprints) in a plant central cell, leading to an asymmetry between the two maternal alleles and the paternal allele, and differential expression of the corresponding alleles in the developing endosperm. This can happen through heterochromatin formation or differential chromatin loop formation.


positive regulation of pyrimidine nucleobase metabolic process

Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving pyrimidine nucleobases.


regulation of phosphatidylserine metabolic process

Any process that modulates the frequency, rate or extent of phosphatidylserine metabolic process.


regulation of aggrephagy

Any process that modulates the frequency, rate or extent of aggrephagy.


positive regulation of chemokine (C-X-C motif) ligand 2 production

Any process that activates or increases the frequency, rate or extent of chemokine (C-X-C motif) ligand 2 production.


positive regulation of methane biosynthetic process from trimethylamine

Any process that activates or increases the frequency, rate or extent of methane biosynthetic process from trimethylamine.


regulation of restriction endodeoxyribonuclease activity

Any process that modulates the frequency, rate or extent of a restriction endodeoxyribonuclease activity, the catalysis of endonucleolytic cleavage of DNA in a site-specific manner, resulting in double-strand breaks.


regulation of (R)-mevalonic acid biosynthetic process

Any process that modulates the frequency, rate or extent of (R)-mevalonic acid biosynthetic process.


nitrogen catabolite regulation of transcription

A transcription regulation process in which the presence of one nitrogen source leads to the modulation of the frequency, rate, or extent of transcription of specific genes involved in the metabolism of other nitrogen sources.


regulation of DNA-templated transcription initiation

Any process that modulates the frequency, rate or extent of DNA-templated transcription initiation.


positive regulation of tetrapyrrole biosynthetic process

Any process that activates or increases the frequency, rate or extent of tetrapyrrole biosynthetic process.


positive regulation of phospholipid metabolic process

Any process that activates or increases the frequency, rate or extent of phospholipid metabolic process.


positive regulation of nuclear cell cycle DNA replication

Any process that activates or increases the frequency, rate or extent of the DNA-dependent DNA replication that occurs in the nucleus of eukaryotic organisms as part of the cell cycle.


negative regulation of triglyceride catabolic process

Any process that decreases the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of triglyceride.


regulation of ent-pimara-8(14),15-diene biosynthetic process

Any process that modulates the frequency, rate or extent of ent-pimara-8(14),15-diene biosynthetic process.


positive regulation of interleukin-21 production

Any process that activates or increases the frequency, rate, or extent of interleukin-21 production.


negative regulation of transforming growth factor beta2 production

Any process that stops, prevents, or reduces the frequency, rate, or extent of production of transforming growth factor-beta2.


negative regulation of methanophenazine metabolic process

Any process that stops, prevents or reduces the frequency, rate or extent of methanophenazine metabolic process.


regulation of siRNA-mediated facultative heterochromatin formation

Any process that modulates the frequency, rate or extent of siRNA-dependent facultative heterochromatin formation.


positive regulation of transcription from a mobile element promoter

Any process that activates or increases the frequency, rate or extent of transcription from a mobile element promoter.


negative regulation of interleukin-26 production

Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-26 production.


positive regulation of reactive oxygen species metabolic process

Any process that activates or increases the frequency, rate or extent of reactive oxygen species metabolic process.


negative regulation of phosphatidylinositol biosynthetic process

Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phosphatidylinositol.


positive regulation of chlorophyll catabolic process

Any process that activates or increases the frequency, rate or extent of chlorophyll catabolic process.


positive regulation of piRNA transcription

Any process that increases the frequency, rate or extent of the synthesis of piRNA.


negative regulation of (+)-kotanin biosynthetic process

Any process that stops, prevents or reduces the frequency, rate or extent of (+)-kotanin biosynthetic process.


regulation of type II interferon production

Any process that modulates the frequency, rate, or extent of interferon-gamma production. Interferon-gamma is also known as type II interferon.


symbiont-mediated suppression of host PKR/eIFalpha signaling

A process in which a symbiont inhibits or disrupts a host PKR (Protein Kinase regulated by RNA) signaling. Host PKR signaling includes targets such as the translation initiation factor eIF2alpha, inhibiting protein synthesis as an antiviral response. The host is defined as the larger of the organisms involved in a symbiotic interaction.


positive regulation of transcription by transcription factor localization

Any process that activates or increases the frequency, rate or extent of DNA-dependent transcription using a mechanism that involves the localization of a transcription factor.


regulation of interleukin-34 production

Any process that modulates the frequency, rate or extent of interleukin-34 production.


regulation of error-prone translesion synthesis

Any process that modulates the frequency, rate or extent of error-prone translesion synthesis.


regulation of transcription by galactose

Any process involving galactose that modulates the frequency, rate or extent or transcription.


siRNA-mediated facultative heterochromatin formation

The formation of facultative heterochromatin into a heterochromatin domain, enriched in histone H3 methylated on lysine 9 (H3K9me), by a process mediated by a small interfering RNA.


positive regulation of heptadecane biosynthetic process

Any process that activates or increases the frequency, rate or extent of heptadecane biosynthetic process.


regulation of T cell cytokine production

Any process that modulates the frequency, rate, or extent of T cell cytokine production.


regulation of interleukin-5 production

Any process that modulates the frequency, rate, or extent of interleukin-5 production.


regulation of cyclic nucleotide catabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of cyclic nucleotides.


negative regulation of violaceol II biosynthetic process

Any process that stops, prevents or reduces the frequency, rate or extent of violaceol II biosynthetic process.


regulation of serotonin biosynthetic process

Any process that modulates the frequency, rate or extent of serotonin biosynthetic process.


regulation of violaceol I biosynthetic process

Any process that modulates the frequency, rate or extent of violaceol I biosynthetic process.


regulation of cytochrome-c oxidase activity

Any process that modulates the frequency, rate or extent of cytochrome-c oxidase activity.


positive regulation of (1->3)-beta-D-glucan biosynthetic process

Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans.


positive regulation of diacylglycerol kinase activity

Any process that activates or increases the frequency, rate or extent of diacylglycerol kinase activity.


negative regulation of chemokine (C-X-C motif) ligand 1 production

Any process that stops, prevents or reduces the frequency, rate or extent of chemokine (C-X-C motif) ligand 1 production.


nitrogen catabolite activation of transcription

A transcription regulation process in which the presence of one nitrogen source leads to an increase in the frequency, rate, or extent of transcription of specific genes involved in the metabolism of other nitrogen sources.


regulation of pteridine metabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving pteridine.


regulation of granulocyte colony-stimulating factor production

Any process that modulates the frequency, rate, or extent of production of granulocyte colony-stimulating factor.


tRNA destabilization

Any process that decreases the stability of a tRNA molecule, making it more vulnerable to degradative processes.


regulation of methanophenazine metabolic process

Any process that modulates the frequency, rate or extent of methanophenazine metabolic process.


negative regulation of interferon-beta production

Any process that stops, prevents, or reduces the frequency, rate, or extent of interferon-beta production.


dosage compensation by inactivation of X chromosome

Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by heterochromatin formation leading to a global inactivation of all, or most of, the genes on one of the X-chromosomes in the XX sex.


negative regulation of mast cell cytokine production

Any process that stops, prevents, or reduces the frequency, rate, or extent of mast cell cytokine production.


induction by virus of host autophagy

Any process in which a virus activates or increases the frequency, rate or extent of autophagy in the host.


negative regulation of monocyte chemotactic protein-1 production

Any process that stops, prevents, or reduces the frequency, rate, or extent of production of monocyte chemotactic protein-1.


positive regulation of tatiopterin biosynthetic process

Any process that activates or increases the frequency, rate or extent of tatiopterin biosynthetic process.


regulation of pentadecane biosynthetic process

Any process that modulates the frequency, rate or extent of pentadecane biosynthetic process.


regulation of DNA-templated DNA replication

Any process that modulates the rate, frequency, or extent of DNA-templated DNA replication, the process in which new strands of DNA are synthesized.


positive regulation of antisense RNA transcription

Any process that increases the frequency, rate or extent of the synthesis of antisense RNA, an RNA molecule complementary in sequence to another RNA or DNA molecule, which, by binding the latter, acts to inhibit its function and/or completion of synthesis, on a template of DNA.


regulation of mitochondrial ATP synthesis coupled electron transport

Any process that modulates the frequency, rate or extent of mitochondrial ATP synthesis coupled electron transport.


positive regulation of glycolytic process through fructose-6-phosphate

Any process that activates or increases the frequency, rate or extent of glycolytic process through fructose-6-phosphate.


regulation of miRNA metabolic process

Any process that modulates the frequency, rate or extent of miRNA metabolic process.


regulation of interleukin-15 production

Any process that modulates the frequency, rate, or extent of interleukin-15 production.


silent mating-type cassette heterochromatin formation

Repression of transcription at silent mating-type loci by alteration of the structure of chromatin.


negative regulation of bile acid metabolic process

Any process that stops, prevents or reduces the frequency, rate or extent of bile acid metabolic process.


negative regulation of transforming growth factor beta3 production

Any process that stops, prevents, or reduces the frequency, rate, or extent of production of transforming growth factor-beta3.


regulation of RNA polymerase III activity

Any process that modulates the frequency, rate or extent of RNA polymerase III activity.


regulation of regulatory ncRNA-mediated heterochromatin formation

Any process that modulates the frequency, rate or extent of small non-coding RNA-mediated heterochromatin formation.


positive regulation of hydrogen peroxide biosynthetic process

Any process that increases the rate, frequency or extent of hydrogen peroxide biosynthesis. The chemical reactions and pathways resulting in the formation of hydrogen peroxide (H2O2), a potentially harmful byproduct of aerobic cellular respiration which can cause damage to DNA.


regulation of phenazine biosynthetic process

Any process that modulates the frequency, rate or extent of phenazine biosynthetic process.


regulation of type III site-specific deoxyribonuclease activity

Any process that modulates the frequency, rate or extent of a type III restriction endodeoxyribonuclease activity.


negative regulation of natural killer cell cytokine production

Any process that stops, prevents, or reduces the frequency, rate, or extent of natural killer cell cytokine production.


regulation of vitamin A metabolic process

Any process that modulates the frequency, rate or extent of vitamin A metabolic process.


regulation of lipid kinase activity

Any process that modulates the frequency, rate or extent of lipid kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a simple or complex lipid.


negative regulation of pentadecane biosynthetic process

Any process that stops, prevents or reduces the frequency, rate or extent of pentadecane biosynthetic process.


regulation of amylopectin catabolic process

Any process that modulates the frequency, rate or extent of amylopectin catabolic process.


positive regulation of telomere maintenance in response to DNA damage

Any process that activates or increases the frequency, rate or extent of telomere maintenance in response to DNA damage.


positive regulation of antimicrobial peptide secretion

Any process that activates or increases the frequency, rate, or extent of antimicrobial peptide secretion.


positive regulation of juvenile hormone catabolic process

Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of juvenile hormone.


positive regulation of myeloid dendritic cell cytokine production

Any process that activates or increases the frequency, rate, or extent of myeloid dendritic cell cytokine production.


regulation of interleukin-11 production

Any process that modulates the frequency, rate, or extent of interleukin-11 production.


negative regulation of interleukin-34 production

Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-34 production.


regulation of pectin biosynthetic process

Any process that modulates the frequency, rate or extent of pectin biosynthetic process.


regulation of hexadecanal metabolic process

Any process that modulates the frequency, rate or extent of hexadecanal metabolic process.


positive regulation of phosphatidylglycerol biosynthetic process

Any process that activates or increases the frequency, rate or extent of phosphatidylglycerol biosynthetic process.


regulation of interleukin-33 production

Any process that modulates the frequency, rate or extent of interleukin-33 production.


regulation of chemokine (C-C motif) ligand 4 production

Any process that modulates the frequency, rate, or extent of production of chemokine (C-C motif) ligand 4.


regulation of interleukin-37 production

Any process that modulates the frequency, rate or extent of interleukin-37 production.


regulation of apoptotic DNA fragmentation

Any process that modulates the frequency, rate or extent of apoptotic DNA fragmentation.


positive regulation of type III interferon production

Any process that activates or increases the frequency, rate, or extent of type III interferon production. Interferon lambda is the only member of the type III interferon found so far.


negative regulation of syringal lignin catabolic process

Any process that stops, prevents or reduces the frequency, rate or extent of syringal lignin catabolic process.


positive regulation of chemokine (C-C motif) ligand 1 production

Any process that activates or increases the frequency, rate, or extent of production of chemokine (C-C motif) ligand 1.


negative regulation of reactive oxygen species metabolic process

Any process that stops, prevents or reduces the frequency, rate or extent of reactive oxygen species metabolic process.


negative regulation of interleukin-16 production

Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-16 production.


positive regulation of pentadecane metabolic process

Any process that activates or increases the frequency, rate or extent of pentadecane metabolic process.