G protein-coupled photoreceptor activity

Combining with incidental electromagnetic radiation, particularly visible light, and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.


ubiquinone biosynthetic process from chorismate

biolink:BiologicalProcess biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:Occurrent biolink:OntologyClass biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

The chemical reactions and pathways resulting in the formation of ubiquinone, beginning with the conversion of chorismate to 4-hydroxybenzoate.


8-oxo-(d)RTP hydrolase activity

biolink:MolecularActivity biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:Occurrent biolink:OntologyClass biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

Catalysis of the reaction: 8-oxo-(d)RTP + H20 = 8-oxo-(d)RMP + diphosphate + H+.


CDP catabolic process

The chemical reactions and pathways resulting in the breakdown of CDP, cytidine (5'-)diphosphate.


MHC class I receptor activity

Combining with an MHC class I protein complex to initiate a change in cellular activity. Class I here refers to classical class I molecules.


cellular response to differentiation-inducing factor 1

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one stimulus.


2',3'-cyclic GMP-AMP binding

Binding to 2',3' cyclic GMP-AMP (cGAMP) nucleotide, a cyclic purine dinucleotide that consists of AMP and GMP units cyclized via 2',5' and 3',5' linkages.


ethanol catabolic process

The chemical reactions and pathways resulting in the breakdown of ethanol, CH3-CH2-OH, a colorless, water-miscible, flammable liquid produced by alcoholic fermentation.


negative regulation by symbiont of host intracellular transport

Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of intracellular transport in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.


Catalysis of the reaction: 2-dehydro-D-gluconate + NADP+ = 2,5-didehydro-D-gluconate + NADPH + H+.


trigeminal ganglion development

The process whose specific outcome is the progression of a trigeminal ganglion over time, from its formation to the mature structure.


SHREC complex localization

Any process in which a SHREC complex is transported to, or maintained in, a specific location.


chondrocyte morphogenesis

The process in which the structures of a chondrocyte are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a chondrocyte.


negative regulation of neuroinflammatory response

Any process that stops, prevents or reduces the frequency, rate or extent of neuroinflammatory response.


sarcomerogenesis

The process in which sarcomeres are added in series within a fiber.


reproductive behavior

The specific behavior of an organism that is associated with reproduction.


regulation of anthocyanin metabolic process

Any process that modulates the frequency, rate or extent of chemical reactions and pathways involving anthocyanins.


protein histidine pros-kinase activity

Catalysis of the reaction: ATP + protein L-histidine = ADP + protein N(pi)-phospho-L-histidine.


Catalysis of the reaction: N-succinyl-L-glutamate + H2O = L-glutamate + succinate.


prephenate(2-) metabolic process

The chemical reactions and pathways involving prephenate(2-).


negative regulation of CD4-positive, alpha-beta T cell costimulation

Any process that stops, prevents or reduces the frequency, rate or extent of CD4-positive, alpha-beta T cell costimulation.


positive regulation of platelet formation

Any process that activates or increases the frequency, rate or extent of platelet formation.


atrial cardiac muscle tissue development

The process whose specific outcome is the progression of cardiac muscle of the atrium over time, from its formation to the mature structure.


regulation of fibroblast chemotaxis

Any process that modulates the frequency, rate or extent of fibroblast chemotaxis.


structural constituent of chromatin

The action of a molecule that contributes to the structural integrity of chromatin.


emericellamide A catabolic process

The chemical reactions and pathways resulting in the breakdown of emericellamide A.


oxidoreductase activity, acting on the aldehyde or oxo group of donors, with a quinone or similar compound as acceptor

Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces a quinone or similar compound.


regulation of collecting lymphatic vessel constriction

Any process that modulates the frequency, rate or extent of collecting lymphatic vessel constriction.


epoxyqueuosine reductase activity

Catalysis of the reaction: epoxyqueuosine in tRNA + reductant = queuosine in tRNA + oxidised reductant.


(S)-carnitine 3-dehydrogenase activity

Catalysis of the reaction: (S)-carnitine + NAD+ = 3-dehydrocarnitine + H+ + NADH.


beta-caryophyllene catabolic process

The chemical reactions and pathways resulting in the breakdown of beta-caryophyllene.


negative regulation of cardiac muscle contraction

Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle contraction.


organophosphate ester transmembrane transporter activity

Enables the transfer of organophosphate esters from one side of a membrane to the other. Organophosphate esters are small organic molecules containing phosphate ester bonds.


reactive oxygen species metabolic process

The chemical reactions and pathways involving a reactive oxygen species, any molecules or ions formed by the incomplete one-electron reduction of oxygen. They contribute to the microbicidal activity of phagocytes, regulation of signal transduction and gene expression, and the oxidative damage to biopolymers.


embryonic retina morphogenesis in camera-type eye

The process in which the anatomical structure of the retina is generated and organized in a camera-type eye during the embryonic life stage.


argininosuccinate synthase activity

Catalysis of the reaction: ATP + L-citrulline + L-aspartate = AMP + diphosphate + (N(omega)-L-arginino)succinate.


NAD-dependent protein deacetylase activity

Catalysis of the removal of one or more acetyl groups from a protein, requiring NAD.


dermal bone morphogenesis

The process in which bone which forms superficially in the organism are generated and organized.


regulation of interleukin-17-mediated signaling pathway

Any process that modulates the frequency, rate or extent of interleukin-17-mediated signaling pathway.


response to dehydroepiandrosterone

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dehydroepiandrosterone stimulus.


chimeric colonial development

Development a structure consisting of multiple co-operating unicellular organisms of the same species, involving cells of more that one genotype.


interleukin-25 receptor activity

Combining with interleukin-25 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


chaeta development

The process whose specific outcome is the progression of a chaeta over time, from its formation to the mature structure. A chaeta is a sensory multicellular cuticular outgrowth of a specifically differentiated cell.


p-coumaroyltriacetic acid lactone synthase activity

Catalysis of the reaction: 2 H+ + 4-coumaryl-CoA + 3 malonyl-CoA( <=> p-coumaroyltriacetic acid lactone + 4 coenzyme A + 3 carbon dioxide.


negative regulation of iron export across plasma membrane

Any process that stops, prevents or reduces the frequency, rate or extent of export of iron ions from inside of a cell, across the plasma membrane and into the extracellular region.


Catalysis of the reaction: all-trans-decaprenyl diphosphate + 4-hydroxybenzoate = 3-decaprenyl-4-hydroxybenzoate + diphosphate.


rhombomere 1 formation

The process that gives rise to rhombomere 1. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.


cannabinoid signaling pathway

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A G protein-coupled receptor signaling pathway initiated by a cannabinoid binding to its receptor on the cell surface, and ending with the regulation of a downstream cellular process, e.g. transcription. Cannabinoids are a class of diverse chemical compounds that include the endocannabinoids and the phytocannabinoids.


regulation of acylglycerol transport

Any process that modulates the frequency, rate or extent of acylglycerol transport.


capsorubin metabolic process

The chemical reactions and pathways involving capsorubin.


hemocyte migration

The directed movement of a hemocyte within the embryo. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. In Drosophila, embryonic hemocytes originate from the head mesoderm as a cluster of cells. The cluster splits into two and one group of cells crosses the amnioserosa. Both populations then spread toward the middle of the embryo and then disperse evenly throughout the embryo.


aflatoxin reductase (coenzyme F420) activity

Catalysis of the reaction: aflatoxin + 1,5-dihydrocoenzyme F420 = aflatoxin with reduced furanocoumarin moiety + coenzyme F420. 1,5-dihydrocoenzyme F420 is also known as reduced coenzyme F420.


polymeric immunoglobulin binding

Binding to a J-chain-containing polymeric immunoglobulin of the IgA or IgM isotypes.


positive regulation of gastric acid secretion

Any process that increases the rate frequency or extent of gastric secretion. Gastric secretion is the regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion.


oocyte animal/vegetal axis specification

The establishment, maintenance and elaboration of the animal/vegetal axis in the oocyte. The animal/vegetal axis of an oocyte is defined by the placement of the nucleus in the oocyte and can sometimes be identified by the asymmetric placement of other substances such as yolk in the oocyte. The pole of the egg that is closest to the nucleus defines the animal end, with the axis passing through the nucleus.


candelabrum cell differentiation

The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature candelabrum cell. Differentiation includes the processes involved in commitment of a neuroblast to a candelabrum cell fate. A candelabrum cell is an inhibitory GABAergic interneuron found in the cerebellar cortex.


regulation of L-tyrosine import across plasma membrane

Any process that modulates the frequency, rate or extent of L-tyrosine import into the cell.


The chemical reactions and pathways resulting in the formation of (+)-epi-alpha-bisabolol.


acyl-CoA oxidase activity

Catalysis of the reaction: acyl-CoA + O2 = trans-2,3-dehydroacyl-CoA + hydrogen peroxide.


cyclohexadienyl dehydrogenase activity

Catalysis of the reaction: L-arogenate + NAD+ = L-tyrosine + NADH + CO2.


Catalysis of the reaction: L-dopa + O2 + H2O + H+ <=> 3,4-dihydroxyphenylacetaldehyde + CO2 + NH(4)+ + H2O2.


positive regulation of mesenchymal cell apoptotic process involved in metanephros development

Any process that activates or increases the frequency, rate or extent of mesenchymal cell apoptotic process involved in metanephros development.


antennal joint morphogenesis

The process in which the anatomical structures of the antennal joint are generated and organized.


tetraterpenoid biosynthetic process

The chemical reactions and pathways resulting in the formation of tetraterpenoid compounds, terpenoids with eight isoprene units.


Catalysis of the reaction: D-galactosamine 6-phosphate + H2O = D-tagatose 6-phosphate + NH3.


maintenance of blood vessel diameter homeostasis by renin-angiotensin

The process in which the diameter of a blood vessel is changed due to activity of the renin-angiotensin system.


symbiont-mediated suppression of host receptor-mediated signal transduction

A process in which a virus interferes with, inhibits or disrupts a receptor-mediated signal transduction pathway in its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.


regulation of vascular associated smooth muscle cell membrane depolarization

Any process that modulates the establishment or extent of a membrane potential in the depolarizing direction away from the resting potential in a vascular smooth muscle cell.


Catalysis of the reaction: UDP-N-acetyl-D-glucosamine = UDP-N-acetyl-D-mannosamine.


modulation of symbiont haustorium neck formation for entry into host

Any process that modulates the frequency, rate or extent of symbiont haustorium neck formation for entry into host. The host is defined as the larger of the organisms involved in a symbiotic interaction.


response to benzoic acid

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a benzoic acid stimulus.


negative regulation of muscle adaptation

Any process that stops, prevents, or reduces the frequency, rate, or extent of muscle adaptation.


nucleoside phosphotransferase activity

Catalysis of the reaction: a nucleotide + a 2'-deoxynucleoside = a nucleoside + a 2'-deoxynucleoside 5'-monophosphate.


regulation of systemic arterial blood pressure by capillary fluid shift

The intrinsic circulatory process resulting from capillary fluid shift that modulates the force with which blood travels through the systemic arterial circulatory system. Capillary fluid shift is the movement of fluid across the capillary membrane between the blood and the interstitial fluid compartment.


violaceol II catabolic process

The chemical reactions and pathways resulting in the breakdown of violaceol II.


teichoic acid metabolic process

The chemical reactions and pathways involving teichoic acid, any polymer occurring in the cell wall, membrane or capsule of Gram-positive bacteria and containing chains of glycerol phosphate or ribitol phosphate residues.


hindbrain formation

The process that gives rise to the hindbrain. This process pertains to the initial formation of a structure from unspecified parts. The hindbrain is the region consisting of the medulla, pons and cerebellum. Areas of the hindbrain control motor and autonomic functions.


R-linalool synthase activity

Catalysis of the reaction: geranyl diphosphate + H2O = (R)-linalool + diphosphate.


Catalysis of the reaction: (2-aminoethyl)phosphonate + pyruvate = L-alanine + phosphonoacetaldehyde.


eye photoreceptor cell differentiation

The process in which a relatively unspecialized cell acquires the specialized features of a photoreceptor cell, as found in the eye, the primary visual organ of most organisms.


dihydromonapterin reductase activity

Catalysis of the reaction: 7,8-dihydromonapterin + NADPH = tetrahydromonapterin + NADP+.


response to interleukin-7

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-7 stimulus.


negative regulation of fibroblast growth factor receptor signaling pathway

Any process that stops, prevents, or reduces the frequency, rate or extent of fibroblast growth factor receptor signaling pathway activity.


ligase activity, forming carbon-sulfur bonds

Catalysis of the joining of two molecules via a carbon-sulfur bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.


regulation of smoothened signaling pathway

Any process that modulates the frequency, rate or extent of smoothened signaling.


regulation of raffinose metabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving raffinose.


trifid subdivision of terminal units involved in ureteric bud branching

The process in which a ureteric bud splits into three units at its end.


negative regulation of potassium ion transmembrane transport

Any process that stops, prevents or reduces the frequency, rate or extent of potassium ion transmembrane transport.


Catalysis of the reaction: RMP + diphosphate = R + 5-phospho-alpha-D-ribose 1-diphosphate.


nephrostome development

The process whose specific outcome is the progression of the nephrostome over time, from its formation to the mature structure. The nephrostome is the opening of the pronephros into the body cavity.


cysteine transmembrane transporter activity

Enables the transfer of cysteine from one side of a membrane to the other.


dermatan 6-sulfotransferase activity

Catalysis of the reaction: 3'-phosphoadenylyl sulfate + dermatan = adenosine 3',5'-bisphosphate + dermatan 6'-sulfate.


gallate decarboxylase activity

Catalysis of the reaction: gallate + H+ = CO2 + pyrogallol.


protein maturation by protein folding

The process of assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure that results in the attainment of the full functional capacity of a protein.


GTP cyclohydrolase IIa activity

Catalysis of the reaction: GTP + 3 H2O = 2-amino-5-formylamino-6-(1-D-ribosylamino)pyrimidin-4(3H)-one 5'-phosphate + 3 H+ + 2 phosphate.


myotome development

The progression of the myotome over time, from its formation to the mature structure. The myotome is the portion of the somite that will give rise to muscle.


positive regulation of maltoheptaose transport

Any process that activates or increases the frequency, rate or extent of maltoheptaose transport.


negative regulation of filamentous growth of a population of unicellular organisms in response to neutral pH

Any process that stops, prevents or reduces the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to neutral pH.


Catalysis of the reaction: 1,4-alpha-D-glucosyl(n) + phosphate = 1,4-alpha-D-glucosyl(n-1) + alpha-D-glucose 1-phosphate. The name should be qualified in each instance by adding the name of the natural substrate, e.g. maltodextrin phosphorylase, starch phosphorylase, glycogen phosphorylase.


regulation of cytokinin-activated signaling pathway

Any process that modulates the frequency, rate or extent of cytokinin signaling.


nitrilotriacetate metabolic process

The chemical reactions and pathways involving nitrilotriacetate, an aminotricarboxylic acid that binds bivalent metal ions in a ratio of 1:1. As an important industrial chelating agent, NTA has been widely used for various radionuclide processing and decontamination procedures, such as textile, paper and pulp processing and water treatment.


Catalysis of the reaction: 5'-methylthioadenosine + phosphate = adenine + 5-methylthio-D-ribose 1-phosphate.


coniferin metabolic process

The chemical reactions and pathways involving coniferin, 4-(3-hydroxyprop-1-en-1-yl)-2-methoxyphenyl beta-D-glucopyranoside.


Catalysis of the reaction: 5-amino-6-(D-ribitylamino)uracil + 4-hydroxyphenylpyruvate + 2 S-adenosyl-L-methionine + H2O = 7,8-didemethyl-8-hydroxy-5-deazariboflavin + 2 5'-deoxyadenosine + 2 L-methionine + oxalate + ammonia + 4 H+.


type III interferon production

The appearance of type III interferon due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Interferon lambda is the only member of the type III interferon found so far.


sensory perception of cold stimulus

The series of events required for an organism to receive a cold temperature stimulus, convert it to a molecular signal, and recognize and characterize the signal.


pre-miRNA 3'-end processing

Any process involved in forming distinct miRNA isoforms from a mature miRNA that differ at their 3'-ends.


seed germination

The physiological and developmental changes that occur in a seed commencing with water uptake (imbibition) and terminating with the elongation of the embryonic axis.


positive regulation of maltotetraose transport

Any process that activates or increases the frequency, rate or extent of maltotetraose transport.


lung proximal/distal axis specification

The establishment, maintenance and elaboration of the proximal/distal axis of the lung. The proximal/distal axis of the lung is defined by a line that runs from the trachea to the alveoli.


crying behavior

The behavior in which an organism sheds tears, often accompanied by non-verbal vocalizations and in response to external or internal stimuli.


retinol transmembrane transporter activity

Enables the transfer of retinol from one side of a membrane to the other. Retinol is vitamin A1, 2,6,6-trimethyl-1-(9'-hydroxy-3',7'-dimethylnona-1',3',5',7'-tetraenyl)cyclohex-1-ene, one of the three components that makes up vitamin A.


16S rRNA (guanine(966)-N(2))-methyltransferase activity

Catalysis of the reaction: S-adenosyl-L-methionine + guanosine(966) in 16S rRNA = N(2)-methylguanosine(966) in 16S rRNA + S-adenosyl-L-homocysteine.


Catalysis of the reaction: 2-methylbutanol + NADP+ = 2-methylbutanal + NADPH + H+.


phosphinothricin metabolic process

The chemical reactions and pathways involving phosphinothricin.


positive regulation of circadian sleep/wake cycle, non-REM sleep

Any process that activates or increases the duration or quality of non-rapid eye movement (NREM) sleep.


alpha-carotene epsilon hydroxylase activity

Catalysis of the reaction: alpha-carotene + NADPH + O2 + H+ = alpha-cryptoxanthin + NADP+ + H2O.


rhamnose biosynthetic process

The chemical reactions and pathways resulting in the formation of rhamnose, the hexose 6-deoxy-L-mannose.


chondrocyte development

The process whose specific outcome is the progression of a chondrocyte over time, from its commitment to its mature state. Chondrocyte development does not include the steps involved in committing a chondroblast to a chondrocyte fate.


regulation of microtubule-based movement

Any process that modulates the rate, frequency, or extent of microtubule-based movement, the movement of organelles, other microtubules and other particles along microtubules, mediated by motor proteins.


regulation of basidiospore formation

Any process that modulates the frequency, rate or extent of basidiospore formation, a process in which a sexually produced fungal spore is formed on a basidium in the fungi Basidiomycetes.


dibasic protein processing

Any protein processing achieved by the cleavage of a peptide bond after two basic amino acids within a protein.


erythromycin D 3''-o-methyltransferase activity

Catalysis of the reaction: S-adenosyl-L-methionine + erythromycin D <=> S-adenosyl-L-homocysteine + erythromycin B + H+.


positive regulation of respiratory burst involved in inflammatory response

Any process that increases the rate, frequency or extent of a phase of elevated metabolic activity, during which oxygen consumption increases made as a defense response ; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals.


Catalysis of the reaction: DNA containing 5-methylcytosine + H2O = DNA with abasic site + 5-methylcytosine. This reaction is the hydrolysis of DNA by cleavage of the N-C1' glycosidic bond between the DNA 5-methylcytosine and the deoxyribose sugar to remove the 5-methylcytosine, leaving an abasic site.


carbamoyl phosphate biosynthetic process

The chemical reactions and pathways resulting in the formation of carbamoyl phosphate, an intermediate in the urea cycle and other nitrogen compound metabolic pathways.


germ-band shortening

The spreading of the amnioserosa from its compressed state to cover the whole of the dorsal surface. Initiating in the thorax and spreading posteriorly, it is accompanied by the transition from a parasegmental to segmental division of the embryo.


detection of oxygen

The series of events in which an oxygen stimulus is received by a cell and converted into a molecular signal.


ethylene metabolic process

The chemical reactions and pathways involving ethylene (C2-H4, ethene), a simple hydrocarbon gas that can function in plants as a growth regulator.


Catalysis of the reaction: 2,3-bis(4-hydroxyphenyl)-1,2-propanediol + O2 = 4-hydroxyphenacyl alcohol + 4-hydroxybenzoate + 2 H+ + 2 e-.


GDP-L-galactose metabolic process

The chemical reactions and pathways involving GDP-L-galactose, a substance composed of L-galactose in glycosidic linkage with guanosine diphosphate.


regulation of forebrain neuron differentiation

Any process that modulates the frequency, rate or extent of forebrain neuron differentiation.


CDP-alcohol phosphotransferase activity

Catalysis of the transfer of a CDP-alcohol group from one compound to another.


wing cell fate specification

The process in which a cell in the larval wing imaginal disc becomes capable of differentiating autonomously into a wing cell, if left in its normal environment.


The chemical reactions and pathways by which a purine deoxyribonucleoside is synthesized from another purine deoxyribonucleoside.


creatine transmembrane transporter activity

Enables the transfer of creatine from one side of a membrane to the other. Creatine is a compound synthesized from the amino acids arginine, glycine, and methionine that occurs in muscle.


diaphragm development

The progression of the diaphragm over time from its initial formation to the mature structure. The diaphragm is a skeletal muscle that is responsible for contraction and expansion of the lungs.


S-acetyltransferase activity

Catalysis of the transfer of an acetyl group to a sulfur atom on the acceptor molecule.


specification of posterior mesonephric tubule identity

The process in which the tubules of the posterior mesonephros acquire their identity.


Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sodium(out)+ malonate(out) = sodium(in) + malonate(in).


modulation of molecular function in another organism

The process in which an organism effects a change in the function of proteins in a second organism.


retinoic acid receptor signaling pathway involved in pronephros anterior/posterior pattern specification

The series of molecular signals generated as a consequence of a retinoic acid receptor binding to one of its physiological ligands that results in the spatial identity of regions along the anterior-posterior axis of the pronephros.


acetone carboxylase activity

Catalysis of the reaction: acetone + ATP + CO2 + 2 H2O = acetoacetate + AMP + 4 H+ + 2 phosphate.


positive regulation of meiotic cell cycle phase transition

Any process that activates or increases the frequency, rate or extent of meiotic cell cycle phase transition.


maintenance of epithelial cell apical/basal polarity

The maintenance of the apicobasal polarity of an epithelial cell.


telium development

The process that leads to the development of a telium, which is a teliospore-bearing sorus of the rust fungi.


cerebellar neuron development

The process whose specific outcome is the progression of a cerebellar neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.


scyllo-inositol dehydrogenase (NADP+) activity

Catalysis of the reaction: scyllo-inositol + NADP <=> 2,4,6/3,5-pentahydroxycyclohexanone + NADPH + H+.


synapse maturation

The process that organizes a synapse so that it attains its fully functional state. Synaptic maturation plays a critical role in the establishment of effective synaptic connections in early development.


negative regulation of developmental process

Any process that stops, prevents or reduces the rate or extent of development, the biological process whose specific outcome is the progression of an organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).


negative regulation of FtsZ-dependent cytokinesis

Any process that stops, prevents, or reduces the frequency, rate or extent of Ftsz-dependent cytokinesis.


light transducer activity

Absorbing energy from one or more photons and transferring their energy to another molecule, usually a protein, within the cell.


positive regulation of axial mesodermal cell fate specification

Any process that activates or increases the frequency, rate or extent of axial mesoderm cell fate specification.


alpha-aminoacyl-tRNA binding

Binding to an alpha-aminoacyl-tRNA.


epi-cedrol synthase activity

Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate + H2O = epi-cedrol + diphosphate.


T-helper 17 cell differentiation

The process in which a relatively unspecialized T cell acquires the specialized features of a T-helper 17 (Th17) cell. A Th17 cell is a CD4-positive, alpha-beta T cell with the phenotype RORgamma-t-positive that produces IL-17.


transport of virus in multicellular host

The transport of a virus between cells in a multicellular organism. The cells can be adjacent or spatially separated (e.g. in different tissues or organs).


negative regulation of protein kinase C signaling

Any process that decreases the frequency, rate, or extent of a series of reactions, mediated by the intracellular serine/threonine kinase protein kinase C, which occurs as a result of a single trigger reaction or compound.


delphinidin 3-O-glucoside biosynthetic process

The chemical reactions and pathways resulting in the formation of delphinidin 3-O-glucoside, a basic, water-soluble anthocyanin responsible for blue coloration of flowers and fruits.


mitotic metaphase chromosome recapture

A mechanism to recapture 'lost' chromosomes (chromosomes which have become detached from the spindle) during metaphase of mitotic chromosome segregation. Chromosomes with unattached kinetochores are migrated along (non polar) spindle microtubules to the mitotic spindle pole body by a combination of microtubule depolymerisation and 'kinetochore sliding' (migration of the chromosome along the microtubule). The chromosome subsequently migrates along the polar spindle microtubule to the metaphase plate.


amino-acid racemase activity

Catalysis of the reaction: an L-amino acid = a D-amino acid.


arabinose metabolic process

The chemical reactions and pathways involving arabinose, arabino-pentose. L-Arabinose occurs both free, for example in the heartwood of many conifers, and in the combined state, as a constituent of plant hemicelluloses, bacterial polysaccharides etc. D-arabinose is a constituent of arabinonucleosides.


AGG codon-amino acid adaptor activity

A triplet codon-amino acid adaptor activity that recognizes an AGG codon.


JUN kinase kinase kinase kinase activity

Catalysis of the phosphorylation and activation of JUN kinase kinase kinases (JNKKKs).


antigen processing and presentation of exogenous peptide antigen

The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC protein complex. The peptide is typically a fragment of a larger exogenous protein which has been degraded within the cell.


negative regulation of cell differentiation involved in embryonic placenta development

Any process that decreases the rate, frequency or extent of cell differentiation that contributes to the progression of the placenta over time, from its initial condition to its mature state.


spleen development

The process whose specific outcome is the progression of the spleen over time, from its formation to the mature structure. The spleen is a large vascular lymphatic organ composed of white and red pulp, involved both in hemopoietic and immune system functions.


dCMP biosynthetic process

The chemical reactions and pathways resulting in the formation of dCMP, deoxycytidine monophosphate.


phosphatidic acid binding

Binding to phosphatidic acid, any of a class of glycerol phosphate in which both the remaining hydroxyl groups of the glycerol moiety are esterified with fatty acids.


positive regulation of floral organ abscission

Any process that increases the rate, frequency, or extent of floral organ shedding, the controlled shedding of floral organs.


regulation of synaptic scaling

A process that modulates synaptic scaling. Synaptic scaling is a form of synaptic plasticity, which entails uniform adjustments in the strength of all synapses on a cell in response to prolonged changes in the electrical activity of the cell.


ergosterol biosynthetic process

The chemical reactions and pathways resulting in the formation of ergosterol, (22E)-ergosta-5,7,22-trien-3-beta-ol, a sterol found in ergot, yeast and moulds.


recognition of pollen

A cell recognition process in which pollen is recognized and either accepted or rejected by cells in the stigma.


canonical Wnt signaling pathway involved in stem cell proliferation

Any canonical Wnt signaling pathway that is involved in stem cell proliferation.


Catalysis of the reaction: acyl-CoA + 1-acyl-sn-glycerol-3-phosphate = CoA + 1,2-diacyl-sn-glycerol-3-phosphate.


extracellular matrix structural constituent conferring tensile strength

A constituent of the extracellular matrix that enables the matrix to resist longitudinal stress.


beta-alanine catabolic process

The chemical reactions and pathways resulting in the breakdown of beta-alanine (3-aminopropanoic acid), an achiral amino acid and an isomer of alanine. It occurs free (e.g. in brain) and in combination (e.g. in pantothenate) but it is not a constituent of proteins.


Catalysis of the reaction: 3-O-[N-acetyl-beta-D-glucosaminyl-(1->3)-N-acetyl-alpha-D-galactosaminyl]-L-seryl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = 3-O-[N-acetyl-beta-D-glucosaminyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->6)]-N-acetyl-alpha-D-galactosaminyl]-L-seryl-[protein] + H+ + UDP.


bacterial-type flagellum organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a bacterial-type flagellum, a motor complex composed of an extracellular helical protein filament coupled to a rotary motor embedded in the cell envelope which functions in cell motility.


Catalysis of the hydrolysis of the alpha-(1->4) linkage of the terminal, non-reducing alpha-D-mannose residues in alpha-D-mannosides.


methylglyoxal reductase (NADH-dependent) activity

Catalysis of the reaction: (R)-lactaldehyde + NAD+ = methylglyoxal + NADH + H+.


D-glutamate metabolic process

The chemical reactions and pathways involving D-glutamate, the D-enantiomer of the amino acid glutamate, i.e. (2R)-2-aminopentanedioic acid.


polysaccharide localization

Any process in which a polysaccharide is transported to, or maintained in, a specific location.


Catalysis of the reaction: L-phenylalanine + 2-oxoglutarate = phenylpyruvate + L-glutamate.


anterior lateral line neuromast hair cell development

The process whose specific outcome is the progression of an anterior lateral line neuromast hair cell over time, from its formation to the mature structure. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. Cell development does not include the steps involved in committing a cell to a specific fate.


Catalysis of the reaction: 6-oxo-2-hydroxycyclohexane-1-carboxyl-CoA + H2O = 3-hydroxypimeloyl-CoA.


negative regulation of glucocorticoid receptor signaling pathway

Any process that stops, prevents or reduces the frequency, rate or extent of glucocorticoid receptor signaling pathway.


Catalysis of the reaction: glycine + 2-oxoglutarate = glyoxylate + L-glutamate.


oxidoreductase activity, acting on phosphorus or arsenic in donors, with a copper protein as acceptor

Catalysis of an oxidation-reduction (redox) reaction in which a phosphorus- or arsenic-containing group acts as a hydrogen or electron donor and reduces a copper protein.


Catalysis of the hydrolysis of pectic acid from the non-reducing end, releasing digalacturonate.


positive regulation of gamma-delta T cell activation

Any process that activates or increases the frequency, rate or extent of gamma-delta T cell activation.


regulation of glucocorticoid receptor signaling pathway

Any process that modulates the frequency, rate or extent of glucocorticoid receptor signaling pathway.


phloem or xylem histogenesis

The process whose specific outcome is the progression of phloem and/or xylem over time, from formation to the mature structure. An example of this process is found in Arabidopsis thaliana.


deoxyribonucleoside binding

Binding to a deoxyribonucleoside, a compound consisting of a purine or pyrimidine nitrogenous base linked to deoxyribose.


dorsal spinal cord interneuron posterior axon guidance

The process in which the migration of an axon growth cone of a dorsal spinal cord interneuron is directed to a specific target site in the posterior direction along the anterior-posterior body axis in response to a combination of attractive and repulsive cues. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism.


blood vessel remodeling

The reorganization or renovation of existing blood vessels.


Catalysis of the reaction: UDP-D-glucose + vitexin = H+ + UDP + vitexin 2''-O-beta-D-glucoside.


metanephric cap specification

The process in which the metanephric cap acquires its identity.


regulation of exonuclease activity

Any process that modulates the frequency, rate or extent of exonuclease activity.


membrane docking

The initial attachment of a membrane or protein to a target membrane. Docking requires only that the proteins come close enough to interact and adhere.


rhombomere 2 morphogenesis

The process in which the anatomical structure of rhombomere 2 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.


mitochondrial tRNA 3'-end processing

The process in which the 3' end of a pre-tRNA molecule is converted to that of a mature tRNA in the mitochondrion.


telomere maintenance via base-excision repair

A telomere maintenance process that occurs by base-excision repair of telomeric DNA in response to DNA damage. Telomeric sequences are particularly susceptible to oxidative DNA damage, due to their G-rich nature.


quinate metabolic process

The chemical reactions and pathways involving quinate, the anion of quinic acid. The acid occurs commonly in plants, either free or as esters, and is used as a medicine.


leg disc anterior/posterior lineage restriction

Formation and/or maintenance of a lineage boundary between anterior and posterior compartments of the leg disc that cells cannot cross, thus separating the populations of cells in each compartment.


limb granular cell fate specification

The process in which a cell becomes capable of differentiating autonomously into an limb granular cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.


bundle of His cell to Purkinje myocyte communication by electrical coupling

The process that mediates signaling interactions between a bundle of His cardiac muscle cell and a Purkinje myocyte by transfer of current between their adjacent cytoplasms via intercellular protein channels.


Catalysis of the reaction: 2 H+ + 2 a reduced ferredoxin + an oxidized thioredoxin = 2 an oxidized ferredoxin + a reduced thioredoxin, involving a 4Fe-4S cluster and an adjacent active-site disulfide.


absorption of UV light

The reception of a (UV light) photon by a cell, UV light being defined as having a wavelength within the range 13.6-400 nm.


positive regulation of lymphocyte differentiation

Any process that activates or increases the frequency, rate or extent of lymphocyte differentiation.


cyanidin 3-O-[2''-O-(xylosyl)-6''-O-(p-coumaroyl) glucoside] 5-O-glucoside malonyltransferase activity

Catalysis of the reaction: cyanidin 3-O-[2''-O-(xylosyl)-6''-O-(p-coumaroyl) glucoside] 5-O-glucoside + malonyl-CoA + H+ <=> cyanidin 3-O-[2''-O-(xylosyl)-6''-O-(p-coumaroyl) glucoside] 5-O-malonylglucoside + coenzyme A.


aliphatic aldoxime dehydratase activity

Catalysis of the reaction: an aliphatic aldoxime = an aliphatic nitrile + H2O.


Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: arabinose(out) + H+(out) = arabinose(in) + H+(in).


response to pyrethroid

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pyrethroid stimulus. Pyrethroids are a group of growth regulators, analogous to insect juvenile hormones, that interfere with the development of insect larvae and are used in the control of insects that are harmful in the adult stage.


positive regulation of Wnt signaling pathway, calcium modulating pathway

Any process that activates or increases the frequency, rate or extent of the series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors leads to an increase in intracellular calcium and activation of protein kinase C (PKC).


chemokine receptor activity

Combining with a chemokine, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. Chemokines are a family of small chemotactic cytokines; their name is derived from their ability to induce directed chemotaxis in nearby responsive cells. All chemokines possess a number of conserved cysteine residues involved in intramolecular disulfide bond formation. Some chemokines are considered pro-inflammatory and can be induced during an immune response to recruit cells of the immune system to a site of infection, while others are considered homeostatic and are involved in controlling the migration of cells during normal processes of tissue maintenance or development. Chemokines are found in all vertebrates, some viruses and some bacteria.


maintenance of transcriptional fidelity during transcription elongation by RNA polymerase II

Suppression of the occurrence of transcriptional errors, such as substitutions and/or insertions of nucleotides that do not correctly match the template base, during the process of transcription elongation from an RNA polymerase II promoter.


negative regulation of arugosin biosynthetic process

Any process that stops, prevents or reduces the frequency, rate or extent of arugosin biosynthetic process.


DNA rewinding

The process in which interchain hydrogen bonds between two single-stranded DNA (ssDNA) are reformed to regenerate double-stranded DNA (dsDNA). ssDNA is often bound and stabilized by proteins such as replication protein A (RPA) to form ssDNA bubbles. The bubbles can be rewound by ATP-dependent motors to reform base pairs between strands and thus dsDNA.


spermidine:oxygen oxidoreductase (3-aminopropanal-forming) activity

Catalysis of the reaction: H2O + O2 + spermidine = 3-aminopropanal + H2O2 + putrescine.


structural constituent of postsynaptic intermediate filament cytoskeleton

The action of a molecule that contributes to the structural integrity of a postsynaptic intermediate filament cytoskeleton.


female analia morphogenesis

The process in which the anatomical structures of the analia of the female are generated and organized. The analia is the posterior-most vertral appendage that develops from the genital disc. An example of this process is found in Drosophila melanogaster.


vein smooth muscle contraction

A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the vein. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The vein is a vessel carrying blood away from the capillary beds.


chitin-based cuticle attachment to epithelium

Attaching of a chitin-containing cuticle to the epithelium underlying it. An example of this process is found in Drosophila melanogaster.


4alpha-carboxy-5alpha-cholesta-8-en-3beta-ol:NAD(P)+ 3-dehydrogenase (decarboxylating) activity

Catalysis of the reaction: 4alpha-carboxy-5alpha-cholesta-8-en-3beta-ol + NAD(P) = 5alpha-cholesta-8-en-3-one + carbon dioxide + NAD(P)H.


Catalysis of the reaction N4-acetylcytidine +H2O = cytidine + acetate.


positive regulation of platelet-derived growth factor receptor signaling pathway

Any process that increases the frequency, rate or extent of the platelet-derived growth factor receptor signaling pathway.


rhombomere structural organization

The process that contributes to the act of creating the structural organization of the rhombomere structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates.


3-methyleneoxindole reductase activity

Catalysis of the reaction: 3-methyloxindole + NADP+ = 3-methyleneoxindole + H+ + NADPH.


neuronal dense core vesicle organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a neuronal dense core vesicle.


nucleobase:monoatomic cation symporter activity

Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: nucleobase(out) + cation(out) = nucleobase(in) + cation(in).


Catalysis of the reaction: poly-cis-polyprenyl diphosphate + isopentenyl diphosphate = diphosphate + a poly-cis-polyprenyl diphosphate longer by one C5 unit.


negative regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation

Any process that stops, prevents, or reduces the frequency, rate or extent of differentiation of CD4-positive, CD25-positive, alpha-beta regulatory T cells.


lipid hydroxylation

The covalent attachment of a hydroxyl group to one or more fatty acids in a lipid.


glutamate catabolic process to butyrate

The chemical reactions and pathways resulting in the breakdown of glutamate into other compounds, including butyrate.


3-hydroxyaspartate aldolase activity

Catalysis of the reaction: (3R)-3-hydroxy-L-aspartate = glycine + glyoxylate.


positive regulation of hyphopodium formation

Any process that activates or increases the frequency, rate or extent of symbiont hyphopodium formation on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.


response to simvastatin

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a simvastatin stimulus. Simvastatin is a statin used as a cholesterol-lowering and anti-cardiovascular disease drug.


positive regulation of respiratory gaseous exchange

Any process that activates or increases the frequency, rate or extent of respiratory gaseous exchange.


protein autosumoylation

The sumoylation by a protein of one or more of its own amino acid residues, or residues on an identical protein.


polyacyltrehalose biosynthetic process

The chemical reactions and pathways resulting in the formation of polyacyltrehalose, a pentaacylated, trehalose-based glycolipid.


prosthetic group biosynthetic process

The chemical reactions and pathways resulting in the formation of a prosthetic group, the non-amino acid portion of certain protein molecules. Prosthetic groups may be inorganic or organic and are usually required for the biological activity of the protein.


brassinosteroid mediated signaling pathway

The series of molecular signals mediated by the detection of brassinosteroid.


regulation of mesenchymal stem cell migration

Any process that modulates the frequency, rate or extent of mesenchymal stem cell migration.


negative regulation of zinc ion transmembrane import

Any process that stops, prevents, or reduces the frequency, rate or extent of zinc ion import.


phytoene metabolic process

The chemical reactions and pathways involving phytoene.


metanephric glomerular epithelial cell development

The process whose specific outcome is the progression of a metanephric glomerular epithelial cell over time, from its formation to the mature structure. Metanephric glomerular epithelial cells are specialized epithelial cells that form part of the metanephric glomerulus; there are two types, metanephric glomerular parietal epithelial cells and metanephric glomerular visceral epithelial cells.


dCTP biosynthetic process

The chemical reactions and pathways resulting in the formation of dCTP, deoxycytidine triphosphate.


The chemical reactions and pathways resulting in the breakdown of (-)-exo-alpha-bergamotene.


negative regulation of amine catabolic process

Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of amines.


stomach body smooth muscle contraction

A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the body of stomach. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The body of stomach is the part of the stomach that lies between the fundus above and the pyloric antrum below; its boundaries are poorly defined.


smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation

The series of molecular signals generated as a consequence of activation of the transmembrane protein Smoothened in cerebellar granule cells that contributes to the regulation of proliferation of the cells.


chemokine (C-C motif) ligand 20 production

The appearance of chemokine (C-C motif) ligand 20 (CCL20) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


monoacylglycerol catabolic process

The chemical reactions and pathways resulting in the breakdown of monoacylglycerol, any ester of glycerol in which any one of its hydroxyl groups has been acylated with a fatty acid, the other being non-esterified.


muscle cell fate commitment

The process in which the cellular identity of muscle cells is acquired and determined.


glycogen catabolic process

The chemical reactions and pathways resulting in the breakdown of glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues.


tRNA end turnover

The process in which the 3'-terminal CCA of a tRNA is removed and restored. This often happens to uncharged tRNA.


beta-lactam antibiotic biosynthetic process

The chemical reactions and pathways resulting in the formation of a beta-lactam antibiotic, any member of a class of natural or semisynthetic antibiotics whose characteristic feature is a strained, four-membered beta-lactam ring. They include the penicillins and many of the cephalosporins.


miltiradiene metabolic process

The chemical reactions and pathways involving miltiradiene.


Catalysis of the reaction: alpha-D-glucose 1-phosphate + GTP = diphosphate + GDP-D-glucose.


apoptotic process involved in development

Any apoptotic process that is involved in anatomical structure development.


mesenchymal-endodermal cell signaling

Any process that mediates the transfer of information between a mesenchymal cell and an endodermal cell.


cyanidin 3-O-glucoside 7-O-glucosyltransferase (feruloyl-glucose dependent) activity

Catalysis of the reaction: cyanidin 3-O-beta-D-glucoside betaine + 1-O-feruloyl-beta-D-glucose <=> cyanidin 3,7-di-O-beta-D-glucoside betaine + ferulate + H+.


septum secundum development

The progression of the septum secundum over time, from its initial formation to the mature structure.


wing disc anterior/posterior pattern formation

The establishment, maintenance and elaboration of the anterior/posterior axis of the wing disc, a precursor to the wing.


high-density lipoprotein particle receptor activity

Combining with a high-density lipoprotein particle and delivering the high-density lipoprotein into the cell via endocytosis.


suppression by symbiont of host phytoalexin production

Any process in which a symbiont stops, prevents, or reduces the frequency, rate or extent of phytoalexin production in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.


cellular response to corticotropin-releasing hormone stimulus

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticotropin-releasing hormone stimulus. Corticotropin-releasing hormone is a peptide hormone involved in the stress response.


geranylgeranyl diphosphate biosynthetic process

The chemical reactions and pathways resulting in the formation of geranylgeranyl diphosphate.


Catalysis of the reaction: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol + NAD+ = NADH + H+ + 2,5-dichlorohydroquinone.


detection of high humidity

The series of events in which high humidity is detected and converted into a molecular signal.


ecdysis-triggering hormone receptor activity

Combining with ecdysis-triggering hormone to initiate a change in cell activity.


ACU codon-amino acid adaptor activity

A triplet codon-amino acid adaptor activity that recognizes an ACU codon.


haltere morphogenesis

The process in which the anatomical structures of a haltere are generated and organized.


brexanolone biosynthetic process

The chemical reactions and pathways resulting in the formation of brexanolone.


lateral mesodermal cell fate specification

The process in which a cell becomes capable of differentiating autonomously into a lateral mesoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.


all-trans-retinol binding

Binding to all-trans-retinol.


glutathione binding

Binding to glutathione; a tripeptide composed of the three amino acids cysteine, glutamic acid and glycine.


asymmetric protein localization involved in cell fate determination

Any process in which a protein is transported to, or maintained in, a specific asymmetric distribution, resulting in the formation of daughter cells of different types.


aliphatic nitrilase activity

Catalysis of the reaction: R-CN + H2O = R-COOH + NH3.


S-alkylthiohydroximate lyase activity

Catalysis of the conversion of a S-alkylthiohydroximate to a thiohydroximate.


Catalysis of the reaction: 2-hydroxycyclohexan-1-one + NADPH + O2 = 6-oxohexanoate + H2O + NADP+.


atrioventricular valve development

The progression of the atrioventricular valve over time, from its formation to the mature structure.


spermidine oxidase (propane-1,3-diamine-forming) activity

Catalysis of the reaction: H2O + O2 + spermidine = 1,3-diaminopropane + 4-aminobutanal + H2O2.


lysine biosynthetic process via alpha-aminoadipate and N2-acetyl-alpha-aminoadipate

The chemical reactions and pathways resulting in the formation of lysine via the intermediates alpha-aminoadipic acid and N2-acetyl-alpha-aminoadipate. This pathway of prokaryotic lysine biosynthesis via alpha-aminoadipate was discovered in the hyper-thermophilic Gram-negative eubacterium Thermus thermophilus. The pathway proceeds as follows: alpha-ketoglutarate is converted to homocitrate, which is metabolized to 3-carboxyhex-2-enedioate and then homoisocitrate. This is then decarboxylated to form alpha-ketoadipate, which is then converted to alpha-aminoadipate. This undergoes acetylation, to form N2-acetyl-alpha-aminoadipate, and is then phosphorylated to give N2-acetyl-alpha-aminoadipyl-delta-phosphate. This is converted to N2-acetyl-alpha-aminoadipate semialdehyde, which is then converted to N2-acetyl-L-lysine. A final deacetylation reaction produces L-lysine.


ommatidial rotation

The process in which photoreceptors are arranged in ommatidia in the dorsal and ventral fields to be mirror images. The polarity is established in the imaginal discs concurrently with cell fate specification.


The phosphorylation by a protein of one or more of its own aspartate amino acid residues, or an aspartate residue on an identical protein.


negative regulation of the force of heart contraction by chemical signal

Any process which decreases the force of heart muscle contraction mediated by chemical signaling, hormonal, autocrine or paracrine.


positive regulation of growth of unicellular organism as a thread of attached cells

Any process that activates or increases the frequency, rate or extent of the process in which cells remain attached after division and form thread-like filaments that may penetrate into a solid growth medium.


geranyl diphosphate metabolic process

The chemical reactions and pathways involving geranyl diphosphate, the universal precursor of the monoterpenes.


anther dehiscence

The dehiscence of an anther to release the pollen grains contained within it.


9-fluorenone-3,4-dioxygenase activity

Catalysis of the reaction: 9-fluorenone + O2 + 2 H+ + 2 e- = 1-hydro-1,1a-dihydroxy-9-fluorenone.


aerobic sulfur oxidation

A sulfur oxidation process that proceeds via the reaction catalyzed by sulfur dioxygenase, and requires the presence of oxygen.


sulochrin oxidase [(-)-bisdechlorogeodin-forming] activity

Catalysis of the reaction: O2 + 2 sulochrin = 2 (2R)-bisdechlorogeodin + 2 H2O.


Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Na+(out) + phosphate(out) = Na+(in) + phosphate(in).


protein-tetrapyrrole linkage

The covalent linking of a tetrapyrrole to a protein.


epithelial cell proliferation involved in Malpighian tubule morphogenesis

The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population and contributing to the shaping of a Malpighian tubule.


N-cyclopropylammelide alkylamino hydrolase activity

Catalysis of the reaction: N-cyclopropylammelide + H2O = cyclopropylamine + cyanuric acid.


squamous basal epithelial stem cell differentiation involved in prostate gland acinus development

The process in which a relatively unspecialized epithelial cell acquires specialized features of a squamous basal epithelial stem cell of the prostate.


metanephric proximal convoluted tubule segment 1 development

The process whose specific outcome is the progression of the S1 portion of the metanephric proximal convoluted tubule over time, from its formation to the mature structure. The S1 portion is the initial portion of the metanephric proximal convoluted tubule and is responsible for avid reabsorption of water and solutes.


cellular detoxification

Any process carried out at the cellular level that reduces or removes the toxicity of a toxic substance. These may include transport of the toxic substance away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance.


cellular response to retinoic acid

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a retinoic acid stimulus.


box H/ACA RNA processing

Any process involved in the conversion of a primary box H/ACA type small RNA transcript into a mature box H/ACA RNA.


negative regulation of receptor signaling pathway via JAK-STAT

Any process that stops, prevents, or reduces the frequency, rate or extent of a receptor signaling pathway via JAK-STAT.


cerebellum development

The process whose specific outcome is the progression of the cerebellum over time, from its formation to the mature structure. The cerebellum is the portion of the brain in the back of the head between the cerebrum and the pons. In mice, the cerebellum controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills.


proline catabolic process

The chemical reactions and pathways resulting in the breakdown of proline (pyrrolidine-2-carboxylic acid), a chiral, cyclic, nonessential alpha-amino acid found in peptide linkage in proteins.


Catalysis of the reaction: 1-palmitoylglycerol-3-phosphate + NADP+ = palmitoylglycerone phosphate + NADPH + H+.


The covalent attachment of a palmitoyl group to a nitrogen (N) atom in an N-terminal cysteine residue to form N-palmitoyl-L-cysteine.


negative regulation of pro-B cell differentiation

Any process that stops, prevents or reduces the frequency, rate or extent of pro-B cell differentiation.


fatty acid methyl ester metabolic process

The chemical reactions and pathways involving fatty acid methyl ester.


glucocorticoid catabolic process

The chemical reactions and pathways resulting in the breakdown of glucocorticoids, hormonal C21 corticosteroids synthesized from cholesterol.


parietal peritoneum development

The process whose specific outcome is the progression of a parietal peritoneum over time, from its formation to the mature structure.


rRNA 3'-end processing

Any process involved in forming the mature 3' end of an rRNA molecule.


protein O-linked glycosylation via hydroxyproline

The glycosylation of proteins via 04 atom of hydroxyproline to form O4-glycosyl-L-hydroxyproline; the most common form is arabinofuranosyl-4-proline.


CD4-positive, alpha-beta T cell cytokine production

Any process that contributes to cytokine production by a CD4-positive, alpha-beta T cell.


imaginal disc lineage restriction

Formation and/or maintenance of a lineage boundary between compartments in an imaginal disc that cells cannot cross, thus separating the populations of cells in each compartment.


stalled ribosome sensor activity

A molecule that recognizes stalled ribosomes and initiates a signaling response.


intramolecular lyase activity

The catalysis of certain rearrangements of a molecule to break or form a ring.


positive regulation of homophilic cell adhesion

Any process that activates or increases the frequency, rate or extent of homophilic cell adhesion.


Catalysis of the reaction: H2O + N6-(2-hydroxyisobutanoyl)-L-lysyl-[protein] = 2-hydroxy-2-methylpropanoate + L-lysyl-[protein].


vanillin synthase activity

Catalysis of the reaction: 3-hydroxy-3-(4-hydroxy-3-methoxyphenyl)propanoyl-CoA = acetyl-CoA + vanillin.


cochlea development

The progression of the cochlea over time from its formation to the mature structure. The cochlea is the snail-shaped portion of the inner ear that is responsible for the detection of sound.


3,4-dihydroxybenzoate catabolic process

The chemical reactions and pathways resulting in the breakdown of 3,4-dihydroxybenzoate.


DN3 thymocyte differentiation

The process in which a relatively unspecialized cell acquires the specialized features of a DN3 thymocyte. A DN3 thymocyte is a CD4-,CD8- thymocyte that is also CD44+,CD25+.


polyadenylation-dependent snoRNA 3'-end processing

Any process involved in forming the mature 3' end of a snoRNA molecule linked to prior polyadenylation of the 3'-end of the precursor snoRNA.


dihydrofolic acid binding

Binding to dihydrofolic acid, a folic acid in which the bicyclic pteridine structure is in the dihydro, partially reduced form; they are intermediates in folate metabolism and are reduced to their tetrahydro, reduced forms.


dissimilatory sulfate reduction

The reduction of sulfate to hydrogen sulfide, which acts as a terminal electron acceptor. Sulfate is activated to adenosine-phosphosulfate (APS) which is then reduced to sulfite, which is in turn reduced to hydrogen sulfide.


neural nucleus development

The biological process whose specific outcome is the progression of a neural nucleus from its initial condition to its mature state. A neural nucleus is an anatomical structure consisting of a discrete aggregate of neuronal soma.


verbascose galactinol:ajugose galactosyltransferase activity

Catalysis of the reaction: verbascose + alpha-D-galactosyl-(1->3)-1D-myo-inositol <=> ajugose + myo-inositol.


regulation of Schwann cell proliferation involved in axon regeneration

Any process that modulates the frequency, rate or extent of Schwann cell proliferation involved in axon regeneration.


exo-alpha-(2->8)-sialidase activity

Catalysis of the hydrolysis of alpha-(2->8)-glycosidic linkages of terminal sialic residues in substrates.


response to biotin

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biotin stimulus.


negative regulation of mast cell apoptotic process

Any process that stops, prevents, or reduces the frequency, rate, or extent of mast cell apoptotic process.


behavioral response to wounding

A behavioral response resulting from wounding.


cytoplasmic translational termination

The process resulting in the release of a polypeptide chain from the ribosome in the cytoplasm, usually in response to a termination codon.


cellular response to nocodazole

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nocodazole stimulus.


peripheral nervous system axon ensheathment

The process in which a Schwann cell membrane closes around an axon in the peripheral nervous system. This can be a myelinating or a non-myelinating neuron-glial interaction.


fibroblast growth factor receptor signaling pathway involved in mammary gland specification

The series of molecular signals initiated by binding of a fibroblast growth factor to its receptor on the surface of al cell in the epidermis resulting in the formation of the mammary line. The mammary line is a ridge of epidermal cells that will form the mammary placodes.


Catalysis of the reactions: a 9-cis-epoxycarotenoid + O2 = 2-cis,4-trans-xanthoxin + a 12'-apo-carotenal; 9-cis-violaxanthin + O2 = 2-cis,4-trans-xanthoxin + (3S,5R,6S)-5,6-epoxy-3-hydroxy-5,6-dihydro-12'-apo-beta-caroten-12'-al; and 9'-cis-neoxanthin + O2 = 2-cis,4-trans-xanthoxin + (3S,5R,6R)-5,6-dihydroxy-6,7-didehydro-5,6-dihydro-12'-apo-beta-caroten-12'-al.


serine 3-dehydrogenase activity

Catalysis of the reaction: L-serine + NADP+ = L-alpha-formylglycine + 2 H+ + NADPH.


peripheral B cell tolerance induction

Tolerance induction of mature B cells in the peripheral lymphoid tissues: the blood, lymph nodes, spleen, and mucosal-associated lymphoid tissue.


acquisition of seed longevity

The acquisition of seed longevity is the ordered series of events during seed development, that prevent embryo deterioration and ROS damage and thus contribute to seed viability over time or in response to adverse environmental conditions. These events include protective (e.g. production of glassy cytoplasm ) and repair (e.g. oxidative stress responses) processes.


wing disc dorsal/ventral pattern formation

The establishment, maintenance and elaboration of the dorsal/ventral axis of the wing disc, a precursor to the adult wing.


meristem development

The process whose specific outcome is the progression of the meristem over time, from its formation to the mature structure.


regulation of brassinosteroid mediated signaling pathway

Any process that modulates the frequency, rate or extent of brassinosteroid mediated signaling pathway.


myosin filament organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a filament composed of myosin molecules.


cellular response to water deprivation

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of water.


abietadiene synthase activity

Catalysis of the reaction: (+)-copalyl diphosphate = (-)-abietadiene + diphosphate.


tropinone reductase activity

Catalysis of the reaction: NADP+ + pseudotropine = H+ + NADPH + tropinone.


cuticle development involved in collagen and cuticulin-based cuticle molting cycle

Synthesis and deposition of a collagen and cuticulin-based noncellular, hardened, or membranous secretion from an epithelial sheet, occurring as part of the molting cycle. An example of this process is found in Caenorhabditis elegans.


regulation of inositol biosynthetic process

Any process that modulates the frequency, rate or extent of inositol biosynthetic process.


envenomation resulting in blood agglutination in another organism

A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with specific proteins binding to cell-surface carbohydrates and causing calcium-dependent agglutination of blood cells in the bitten organism.


Enables the directed movement of lysophospholipids from one side of a membrane to the other. A lysophospholipid is a phospholipid that lacks one of its fatty acyl chains; it is an intermediate formed during digestion of dietary and biliary phospholipids.


Catalysis of the reaction: 3-methoxy-5-hydroxytoluene + S-adenosyl-L-methionine = H+ + 3,5-dimethoxytoluene + S-adenosyl-L-homocysteine.


negative regulation of xenobiotic detoxification by transmembrane export across the plasma membrane

Any process that stops, prevents or reduces the frequency, rate or extent of xenobiotic transmembrane export. A xenobiotic is a compound foreign to the organim exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical.


L-gulonolactone oxidase activity

Catalysis of the reaction: L-gulono-1,4-lactone + O2 = L-xylo-hex-3-ulonolactone + H2O2.


interleukin-33 production

The appearance of interleukin-33 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


O-acetyltransferase activity

Catalysis of the transfer of an acetyl group to an oxygen atom on the acceptor molecule.


hepatic stellate cell differentiation

The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a hepatic stellate cell.


GARP complex binding

Binding to a GARP complex.


dTDP-mannose biosynthetic process

The chemical reactions and pathways resulting in the formation of dTDP-mannose, a substance composed of mannose in glycosidic linkage with deoxyribosylthymine diphosphate.


calcidiol 1-monooxygenase activity

Catalysis of the reaction: calcidiol + H+ + NADPH + O2 = calcitriol + H2O + NADP+.


chronic inflammatory response

Inflammation of prolonged duration (weeks or months) in which active inflammation, tissue destruction, and attempts at repair are proceeding simultaneously. Although it may follow acute inflammation, chronic inflammation frequently begins insidiously, as a low-grade, smoldering, often asymptomatic response.


sensory processing

Any neural process required for an organism to sense and interpret the dimensions of a sensory experience: modality, location, intensity and affect.


cell differentiation involved in pronephros development

The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the pronephros as it progresses from its formation to the mature state.


amphiregulin production

The appearance of amphiregulin due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Amphiregulin (AREG) is a ligand of the epidermal growth factor receptor (EGFR), a widely expressed transmembrane tyrosine kinase. AREG is synthesized as a membrane-anchored precursor protein that can engage in juxtacrine signaling on adjacent cells. Alternatively, after proteolytic processing by cell membrane proteases, mainly TACE/ADAM17, AREG is secreted and behaves as an autocrine or paracrine factor.


positive regulation of blood pressure in another organism

A process by which one organism increases the force with which blood travels through the circulatory system of another organism.


foraging behavior

Behavior by which an organism locates food.


regulation of calcidiol 1-monooxygenase activity

Any process that modulates the rate, frequency or extent of calcidiol 1-monooxygenase activity. Calcidiol 1-monooxygenase activity is catalysis of the reaction: calcidiol + NADPH + H+ + O2 = calcitriol + NADP+ + H2O.


sepal giant cell differentiation

The process in which a relatively unspecialized cell acquires specialized features of a sepal giant cell. A sepal giant cell is a pavement cell that is part of the sepal epidermis and stretches one fifth the length of the sepal with a chromosome content of 16C.


positive regulation of cell size

Any process that increases cell size.


ureter smooth muscle cell differentiation

The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell in the ureter.


regulation of monoatomic anion transport

Any process that modulates the frequency, rate or extent of the directed movement of anions, atoms or small molecules with a net negative charge into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


cellular response to leucine starvation

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of leucine.


regulation of intestinal epithelial cell development

Any process that modulates the frequency, rate or extent of intestinal epithelial cell development.


Catalysis of the reaction: 4-coumaroyl-CoA + a flavonol 3-O-[beta-D-glucosyl-(1->2)-beta-D-glucosyl-(1->2)-beta-D-glucoside] = CoA + a flavonol 3-O-[6-(4-coumaroyl)-beta-D-glucosyl-(1->2)-beta-D-glucosyl-(1->2)-beta-D-glucoside].


MAPK-activating adrenergic receptor signaling pathway

The series of molecular signals generated as a consequence of an adrenergic receptor binding to its physiological ligand and leading to the activation of a MAP kinase cascade.


positive regulation of protein kinase C signaling

Any process that increases the frequency, rate, or extent of a series of reactions, mediated by the intracellular serine/threonine kinase protein kinase C, which occurs as a result of a single trigger reaction or compound.


protein insertion into membrane raft

The process in which a protein is incorporated into a membrane raft. Membrane rafts are small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes.


cellobiose binding

Binding to cellobiose, a disaccharide that represents the basic repeating unit of cellulose.


receptor catabolic process

The chemical reactions and pathways resulting in the breakdown of a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.


Catalysis of the reaction: L-arginyl-[protein] + NAD+ = H+ + (ADP-D-ribosyl)-L-arginyl-[protein] + nicotinamide.


Catalysis of the reaction: N-methyl-3-aminomethylindole + S-adenosyl-L-methionine = H+ + gramine + S-adenosyl-L-homocysteine.


vestibulocochlear nerve morphogenesis

The process in which the anatomical structure of the vestibulocochlear nerve is generated and organized. This sensory nerve innervates the membranous labyrinth of the inner ear. The vestibular branch innervates the vestibular apparatus that senses head position changes relative to gravity. The auditory branch innervates the cochlear duct, which is connected to the three bony ossicles which transduce sound waves into fluid movement in the cochlea.


regulation of retinal cell programmed cell death

Any process that modulates the frequency, rate or extent of programmed cell death that occurs in the retina.


iron incorporation into iron-sulfur cluster via pentakis-L-cysteinyl L-histidino nickel tetrairon pentasulfide

The incorporation of iron into a nickel-iron-sulfur cluster via pentakis-L-cysteinyl L-histidino nickel tetrairon pentasulfide, found in carbon monoxide dehydrogenase.


somatic diversification of immune receptors by N region addition

The addition of variable numbers of random nucleotides by terminal deoxytransferase in the N regions of heavy chain immunoglobulin and T cell receptor genes. N regions are found at the V-D, D-D, V-J, and D-J recombinational junctions, depending on the immune receptor gene.


myelination of lateral line nerve axons

The formation of compact myelin sheaths around the axons of a lateral line nerve.


gallate catabolic process

The chemical reactions and pathways resulting in the breakdown of gallate, the anion of gallic acid (3,4,5-trihydroxybenzoic acid).


hydrolase activity, acting on acid halide bonds, in C-halide compounds

Catalysis of the hydrolysis of any acid halide bond in substances containing halogen atoms in organic linkage.


detection of pH by chemoreceptor signaling

The process in which information about the levels of hydrogen ions are received and are converted to a molecular signal by chemoreceptors.


pharynx morphogenesis

The process in which the anatomical structures of the pharynx are generated and organized.


monoacylglycerol metabolic process

The chemical reactions and pathways involving monoacylglycerol, any ester of glycerol in which any one of its hydroxyl groups has been acylated with a fatty acid, the other being non-esterified.


mammary gland branching involved in pregnancy

The process in which the branching structure of the mammary gland duct is generated and organized as a part of pregnancy.


amyloid-beta formation

The generation of amyloid-beta by cleavage of the amyloid precursor protein (APP).


arginine catabolic process

The chemical reactions and pathways resulting in the breakdown of arginine, 2-amino-5-(carbamimidamido)pentanoic acid.


peptidyl-histidine methylation

The methylation of peptidyl-L-histidine to form peptidyl-L-1'-methyl-L-histidine (otherwise known as tau-methylhistidine, tele-methylhistidine) or peptidyl-L-3'-methyl-L-histidine (otherwise known as pi-methylhistidine, pros-methylhistidine).


epithelial cell differentiation involved in embryonic placenta development

The process in which a trophoblast cell acquires specialized features of an epithelial cell of the placental labyrinthine layer.


principal sensory nucleus of trigeminal nerve development

The process whose specific outcome is the progression of the pontine nucleus over time, from its formation to the mature structure.


regulation of NK T cell differentiation

Any process that modulates the frequency, rate or extent of natural killer T cell differentiation.


regulation of lymphangiogenesis

Any process that modulates the frequency, rate or extent of lymphangiogenesis.


exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

Exonucleolytic digestion of a pre-rRNA molecule to generate the mature 3'-end of a 5.8S rRNA molecule derived from an originally tricistronic pre-rRNA transcript that contained the Small Subunit (SSU) rRNA, the 5.8S rRNA, and the Large Subunit (LSU) rRNA in that order from 5' to 3' along the primary transcript.


negative regulation of asexual reproduction

Any process that stops, prevents or reduces the frequency, rate or extent of asexual reproduction.


NAD-cap decapping

Cleavage of the 5'-NAD-cap of an RNA. The NAD-cap is present at the 5'-end of some RNAs in both bacetria and eukaryotes. While it promotes RNA stability in bacteria, it promotes RNA decay in eukaryotes.


keratinocyte differentiation

The process in which a relatively unspecialized cell acquires specialized features of a keratinocyte.


regulation of cell wall integrity MAPK cascade

Any process that modulates the frequency, rate or extent of MAPK cascade involved in cell wall organization or biogenesis.


PSII associated light-harvesting complex II catabolic process

The chemical reactions and pathways resulting in the breakdown of one or more components of the light-harvesting complex of photosystem II.


extracellular ammonia-gated monoatomic ion channel activity

Enables the transmembrane transfer of an ion by a channel that opens when extracellular ammonia (NH3) has been bound by the channel complex or one of its constituent parts.


Catalysis of the reaction: 2-oxoglutarate + L-histidine = 3-(imidazol-5-yl)pyruvate + L-glutamate.


guanine salvage

Any process that generates guanine, 2-amino-6-hydroxypurine, from derivatives of it without de novo synthesis.


camalexin metabolic process

The chemical reactions and pathways involving camalexin, an indole phytoalexin.


positive regulation of leukocyte proliferation

Any process that activates or increases the frequency, rate or extent of leukocyte proliferation.


dimethylmaleate hydratase activity

Catalysis of the reaction: (2R,3S)-2,3-dimethylmalate = dimethylmaleate + H2O.


monocyte homeostasis

The process of regulating the proliferation and elimination of monocytes such that the total number of monocytes within a whole or part of an organism is stable over time in the absence of an outside stimulus.


poly(ribitol phosphate) teichoic acid metabolic process

The chemical reactions and pathways involving poly(ribitol phosphate) teichoic acid.


regulation of necroptotic process

Any process that modulates the rate, frequency or extent of a necroptotic process, a necrotic cell death process that results from the activation of endogenous cellular processes, such as signaling involving death domain receptors or Toll-like receptors.


nicotinic acid riboside metabolic process

The chemical reactions and pathways involving nicotinic acid riboside, the product of the formation of a glycosidic bond between ribose and nicotinic acid.


positive regulation of egg-laying behavior

Any process that activates or increases the frequency, rate or extent of oviposition.


GPCR sweet taste receptor activity

A G protein-coupled receptor activity that is responsible for the sense of sweet taste.


thiamine transmembrane transporter activity

Enables the transfer of thiamine from one side of a membrane to the other. Thiamine is vitamin B1, a water soluble vitamin present in fresh vegetables and meats, especially liver.


sulfur incorporation into metallo-sulfur cluster

The incorporation of exogenous sulfur into a metallo-sulfur cluster.


histone H4K5 acetyltransferase activity

Catalysis of the reaction: acetyl-CoA + histone H4 L-lysine (position 5) = CoA + histone H4 N6-acetyl-L-lysine (position 5).


cellular response to non-ionic osmotic stress

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of non-ionic solutes (e.g. mannitol, sorbitol) in the environment.


Catalysis of the reaction: 5,10-methylenetetrahydrofolate + tRNA containing uridine at position 54 + FADH + H+ = tetrahydrofolate + tRNA containing ribothymidine at position 54 + FAD+.


superoxide dismutase activity

Catalysis of the reaction: 2 superoxide + 2 H+ = O2 + hydrogen peroxide.


mesodermal cell fate commitment

The cell differentiation process that results in commitment of a cell to become part of the mesoderm.


alpha-zeacarotene catabolic process

The chemical reactions and pathways resulting in the breakdown of alpha-zeacarotene.


D-leucine metabolic process

The chemical reactions and pathways involving D-leucine.


regulation of filamentous growth of a population of unicellular organisms in response to starvation

Any process that modulates the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to starvation.


response to benzene

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a benzene stimulus.


dibenzothiophene desulfurization

The removal of the sulfur atom from dibenzothiophene, a substance composed of two benzene rings linked by one sulfide bond and one carbon-carbon bond.


trimethylarsine oxidase activity

Catalysis of the reaction: trimethylarsine oxide + 2 H+ + 2 e- = trimethylarsine + H2O.


Catalysis of the reaction: homocystine + 2 reduced glutathione = oxidized glutathione + 2 homocysteine.


reproduction of a single-celled organism

The biological process in which new individuals are produced by one or two single-celled organisms. The new individuals inherit some proportion of their genetic material from the parent or parents.


Catalysis of the reaction: 5-amino-4-chloro-2-(2,3-dihydroxyphenyl)pyridazin-3(2H)-one + O2 = 5-amino-4-chloro-2-(2-hydroxymuconoyl)pyridazin-3(2H)-one + 2 H+.


amino-acid betaine biosynthetic process

The chemical reactions and pathways resulting in the formation of any betaine, the N-trimethyl derivative of an amino acid.


polyterpenoid catabolic process

The chemical reactions and pathways resulting in the breakdown of polyterpenoid compounds, terpenoids with more than eight isoprene units.


regulation of signal transduction by p53 class mediator

Any process that modulates the frequency, rate or extent of signal transduction by p53 class mediator.


determination of digestive tract left/right asymmetry

Determination of the asymmetric location of various parts of the digestive tract with respect to the left and right halves of the organism. The digestive tract is the anatomical structure through which food passes and is processed.


establishment of Golgi localization

The directed movement of the Golgi to a specific location.


grooming behavior

The specific behavior of an organism relating to grooming, cleaning and brushing to remove dirt and parasites.


helper T cell extravasation

The migration of a helper T cell from the blood vessels into the surrounding tissue. A helper T-cell is an effector T cell that provides help in the form of secreted cytokines to other immune cells.


induction of conjugation upon carbon starvation

The process in which a cell initiates conjugation with cellular fusion upon carbon starvation.


metalloendopeptidase activity involved in amyloid precursor protein catabolic process

Any metalloendopeptidase activity that is involved in amyloid precursor protein catabolic process.


pantothenate kinase activity

Catalysis of the reaction: ATP + pantothenate = ADP + D-4'-phosphopantothenate.


positive regulation of response to salt stress

Any process that activates or increases the frequency, rate or extent of response to salt stress.


histone H3K27me2/H3K27me3 demethylase activity

Catalysis of the removal of a methyl group from a tri- or a dimethyl-lysine residue at position 27 of the histone H3 protein. This is a dioxygenase reaction that is dependent on Fe(II) and 2-oxoglutarate.


cellular response to bile acid

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bile acid stimulus.


box C/D snoRNP complex binding

Binding to a box C/D snoRNP complex.


Catalysis of the reaction: nicotinate + UDP-D-glucose = N-(beta-D-glucosyl)nicotinate + UDP.


DNA synthesis involved in double-strand break repair via homologous recombination

The synthesis of DNA that contributes to the process of double-strand break repair via homologous recombination.


negative regulation of AV node cell action potential

Any process that stops, prevents or reduces the frequency, rate or extent of AV node cell action potential.


Catalysis of the reaction 6-deoxy-6-sulfofructose-1-phosphate = 3-sulfolactaldehyde + dihydroxyacetone phosphate.


Catalysis of the reaction: agmatine + S-adenosylmethioninamine = N1-aminopropylagmatine + 5'-methylthioadenosine.


adaptive immune response based on somatic recombination of immune receptors built from leucine-rich repeat domains

An immune response mediated by lymphocytes expressing specific receptors for antigen produced through a somatic diversification process that includes somatic recombination of variable lymphocyte receptors (VLR) incorporating leucine-rich repeat (LRR) domains, and allowing for enhanced responses upon subsequent exposures to the same antigen (immunological memory). Examples of this process are found in jawless fish, including the lampreys (Petromyzontidae) and hagfishes (Myxinidae).


thyroid-stimulating hormone-secreting cell differentiation

The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a thyroid-stimulating hormone-secreting cell. A thyroid-stimulating hormone-secreting cell is a basophil cell of the anterior pituitary that produces thyroid-stimulating hormone, thyrotrophin.


GDP-D-glucose phosphorylase activity

Catalysis of the reaction: GDP-alpha-D-glucose + phosphate = alpha-D-glucose-1-phosphate + GDP.


2-phenanthrol sulfotransferase activity

Catalysis of the reaction: 2-phenanthrol + X-SO3(-) = HX + 2-phenanthrylsulfate.


formation of animal organ boundary

The regionalization process that specifies animal organ primordium boundaries resulting in a restriction of organogenesis to a limited spatial domain and keeping the organ separate from surrounding tissues.


Catalysis of the reaction: 2-trans,-6-trans-farnesol + ATP = 2-trans,-6-trans-farnesyl monophosphate + ADP + H+.


gibberellin A13,oxoglutarate:oxygen oxidoreductase activity

Catalysis of the reaction: gibberellin A13 + 2-oxoglutarate + O2 <=> gibberellin A43 + succinate + carbon dioxide.


Catalysis of the reaction: P(1),P(4)-bis(5'-nucleosyl)tetraphosphate + H2O = NTP + NMP. Acts on bis(5'-guanosyl)-, bis(5'-xanthosyl)-, bis(5'-adenosyl)- and bis(5'-uridyl)-tetraphosphate.


protein localization to equatorial microtubule organizing center

A process in which a protein is transported to, or maintained in, a location within an equatorial microtubule organizing center.


ansamycin metabolic process

The chemical reactions and pathways involving ansamycins, any of a group of complex macrolactam compounds characterized by a cyclic structure in which an aliphatic ansa chain forms a bridge between two non-adjacent positions of a cyclic p-system; many exhibit antibacterial, antifungal or antitumor activity.


tetracyclic triterpenoid metabolic process

The chemical reactions and pathways involving tetracyclic triterpenoid compounds, terpenoids with six isoprene units and 4 carbon rings.


AP-3 adaptor complex binding

Binding to an AP-3 adaptor complex. The AP-3 adaptor complex is a heterotetrameric AP-type membrane coat adaptor complex that consists of beta3, delta, mu3 and sigma3 subunits and is found associated with endosomal membranes. In at least humans, the AP-3 complex can be heterogeneric due to the existence of multiple subunit isoforms encoded by different genes (beta3A and beta3B, mu3A and mu3B, and sigma3A and sigma3B).


negative regulation of osteoclast differentiation

Any process that stops, prevents, or reduces the frequency, rate or extent of osteoclast differentiation.


N-substituted formamide deformylase activity

Catalysis of the reaction: N-benzylformamide + H2O = formate + benzylamine.


ubiquinone binding

Binding to ubiquinone, a quinone derivative with a tail of isoprene units.


epi-isozizaene synthase activity

Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = (+)-epi-isozizaene + diphosphate.


protein farnesyltransferase activity

Catalysis of the reaction: farnesyl diphosphate + protein-cysteine = S-farnesyl protein + diphosphate.


response to salt stress

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.


positive regulation of early endosome to recycling endosome transport

Any process that activates or increases the frequency, rate or extent of early endosome to recycling endosome transport.


positive regulation of neuron migration

Any process that activates or increases the frequency, rate or extent of neuron migration.


presynaptic signal transduction

Signal transduction in which the initial step occurs in a presynapse.


outer hair cell apoptotic process

Any apoptotic process in an outer hair cell.


protein localization to somatodendritic compartment

A process in which a protein is transported to or maintained in a location within the somatodendritic compartment.


detection of chemical stimulus involved in sensory perception of umami taste

The series of events required for a umami taste stimulus to be received and converted to a molecular signal. Umami taste is the savory taste of meats and other foods that are rich in glutamates.


regulation of phospholipase D activity

Any process that modulates the frequency, rate or extent of phospholipase D activity.


glycerol dehydrogenase (acceptor) activity

Catalysis of the reaction: A + glycerol = AH(2) + glycerone.


regulation of vascular endothelial growth factor signaling pathway

Any process that modulates the frequency, rate or extent of vascular endothelial growth factor signaling pathway.


CD8-positive, alpha-beta T cell proliferation

The expansion of a CD8-positive, alpha-beta T cell population by cell division.


tetrapyrrole biosynthetic process

The chemical reactions and pathways leading to the formation of tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next.


regulation of arbuscule formation for nutrient acquisition from host

Any process that modulates the frequency, rate or extent of symbiont arbuscule formation for nutrient acquisition from host. The host is defined as the larger of the organisms involved in a symbiotic interaction.


R-lactaldehyde reductase activity

Catalysis of the reaction: (R)-propane-1,2-diol + NAD+ = (R)-lactaldehyde + NADH + H+.


hydroxyectoine binding

Binding to hydroxyectoine.


innate immune response-inhibiting signal transduction

The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately leading to inhibition of an innate immune response.


negative regulation of plasmatocyte differentiation

Any process that stops, prevents, or reduces the frequency, rate or extent of plasmatocyte differentiation.


sucrose-phosphate synthase activity

Catalysis of the reaction: UDP-glucose + D-fructose 6-phosphate = UDP + sucrose 6-phosphate.


emericellin metabolic process

The chemical reactions and pathways involving emericellin.


negative regulation of pigment cell differentiation

Any process that stops, prevents, or reduces the frequency, rate or extent of pigment cell differentiation.


CAMKK-AMPK signaling cascade

The series of molecular signals in which calmodulin-dependent protein kinase activity enabled by a CAMKK directly activates an AMPK. The cascade begins with calmodulin binding calcium which in turn binds CAMKK enabling its calmodulin-dependent protein kinase activity. The cascade ends with AMP-activated protein kinase activity.


dolichyldiphosphatase activity

Catalysis of the reaction: dolichyl diphosphate + H2O = dolichyl phosphate + phosphate.


Catalysis of the reaction: 2,5-dihydroxybenzoate + UDP-alpha-D-glucose <=> 2,5-dihydroxybenzoate 5-O-beta-D-glucoside + UDP + H+.


diterpenoid catabolic process

The chemical reactions and pathways resulting in the breakdown of diterpenoid compounds, terpenoids with four isoprene units.


beta-adrenergic receptor activity

Combining with epinephrine or norepinephrine to initiate a change in cell activity via activation of a G protein, with pharmacological characteristics of beta-adrenergic receptors; the activity involves transmitting the signal to the Gs alpha subunit of a heterotrimeric G protein.


negative regulation of developmental pigmentation

Any process that decreases the frequency, rate or extent of the developmental process that results in the deposition of coloring matter in an organism.


5-methylcytosine metabolic process

The chemical reactions and pathways involving 5-methylcytosine, a methylated base of DNA.


oxidative demethylation

The process of removing one or more methyl groups from a molecule, involving the oxidation (i.e. electron loss) of one or more atoms in the substrate.


hydrogen dehydrogenase (NADP+) activity

Catalysis of the reaction: NADP+ + H2 = NADPH + H+.


TTP metabolic process

The chemical reactions and pathways involving TTP, ribosylthymine triphosphate.


dentate nucleus development

The process whose specific outcome is the progression of the dentate nucleus over time, from its formation to the mature structure.


amidophosphoribosyltransferase activity

Catalysis of the reaction: 5-phospho-beta-D-ribosylamine + L-glutamate + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + L-glutamine + H2O.


negative regulation of neuronal signal transduction

Any process that stops, prevents or reduces the frequency, rate or extent of neuronal signal transduction.