positive regulation of mast cell chemotaxis

Any process that increases the rate, frequency or extent of mast cell chemotaxis. Mast cell chemotaxis is the movement of a mast cell in response to an external stimulus.


positive regulation of macrophage chemotaxis

biolink:BiologicalProcess biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:Occurrent biolink:OntologyClass biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

Any process that increases the rate, frequency or extent of macrophage chemotaxis. Macrophage chemotaxis is the movement of a macrophage in response to an external stimulus.


regulation of B cell chemotaxis

Any process that modulates the frequency, rate or extent of B cell chemotaxis.


regulation of myeloid dendritic cell chemotaxis

Any process that modulates the frequency, rate or extent of myeloid dendritic cell chemotaxis.


positive regulation of monocyte chemotaxis

Any process that increases the frequency, rate, or extent of monocyte chemotaxis.


negative regulation of monocyte chemotaxis

Any process that decreases the frequency, rate, or extent of monocyte chemotaxis.


negative regulation of natural killer cell chemotaxis

Any process that stops, prevents or reduces the frequency, rate or extent of natural killer cell chemotaxis.


negative regulation of mast cell chemotaxis

Any process that decreases the rate, frequency or extent of mast cell chemotaxis. Mast cell chemotaxis is the movement of a mast cell in response to an external stimulus.


negative regulation of granulocyte chemotaxis

Any process that decreases the rate, frequency or extent of granulocyte chemotaxis. Granulocyte chemotaxis is the movement of a granulocyte in response to an external stimulus.


positive regulation of natural killer cell chemotaxis

Any process that activates or increases the frequency, rate or extent of natural killer cell chemotaxis.


regulation of T cell chemotaxis

Any process that modulates the rate, frequency or extent of T cell chemotaxis. T cell chemotaxis is the directed movement of a T cell in response to an external stimulus.


positive regulation of dendritic cell chemotaxis

Any process that activates or increases the frequency, rate or extent of dendritic cell chemotaxis.


positive regulation of eosinophil chemotaxis

Any process that activates or increases the frequency, rate or extent of eosinophil chemotaxis.


positive regulation of granulocyte chemotaxis

Any process that increases the rate, frequency or extent of granulocyte chemotaxis. Granulocyte chemotaxis is the movement of a granulocyte in response to an external stimulus.


regulation of mast cell chemotaxis

Any process that modulates the rate, frequency or extent of mast cell chemotaxis. Mast cell chemotaxis is the movement of a mast cell in response to an external stimulus.


negative regulation of dendritic cell chemotaxis

Any process that stops, prevents or reduces the frequency, rate or extent of dendritic cell chemotaxis.


regulation of granulocyte chemotaxis

Any process that modulates the rate, frequency or extent of granulocyte chemotaxis. Granulocyte chemotaxis is the movement of a granulocyte in response to an external stimulus.


regulation of lymphocyte chemotaxis

Any process that modulates the frequency, rate or extent of lymphocyte chemotaxis.


regulation of dendritic cell chemotaxis

Any process that modulates the frequency, rate or extent of dendritic cell chemotaxis.


positive regulation of T cell chemotaxis

Any process that increases the rate, frequency or extent of T cell chemotaxis. T cell chemotaxis is the directed movement of a T cell in response to an external stimulus.


L-Ala-D/L-Glu epimerase activity

biolink:MolecularActivity biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:Occurrent biolink:OntologyClass biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

Catalysis of the reaction: L-alanyl-D-glutamate = L-alanyl-L-glutamate.


apoptotic process involved in salivary gland cavitation

Any apoptotic process in which the solid core of the gland is hollowed out to form the duct.


posterior lateral line ganglion neuron differentiation

The process in which a relatively unspecialized cell acquires specialized features of a neuron of the posterior lateral line ganglion.


peripheral nervous system neuron differentiation

The process in which a relatively unspecialized cell acquires specialized features of a neuron whose cell body resides in the peripheral nervous system.


lateral line ganglion neuron differentiation

The process in which a relatively unspecialized cell acquires specialized features of a lateral line ganglion neuron.


anterior lateral line ganglion neuron differentiation

The process in which a relatively unspecialized cell acquires specialized features of a neuron of the anterior lateral line ganglion.


The process of coupling tyrosine to tyrosyl-tRNA in a mitochondrion, catalyzed by tyrosyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.


regulation of Golgi calcium ion export

Any process that modulates the frequency, rate or extent of Golgi calcium ion export.


negative regulation of calcium import into the mitochondrion

Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion import into the mitochondrion.


positive regulation of calcium ion transport into cytosol involved in cellular response to salt stress

Any positive regulation of calcium ion transport into cytosol that is involved in cellular response to salt stress.


regulation of store-operated calcium entry

Any process that modulates the frequency, rate or extent of store-operated calcium entry.


positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion

biolink:Pathway biolink:BiologicalProcess biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:OntologyClass biolink:Occurrent biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

Any process that activates, maintains or increases the frequency, rate or extent of skeletal muscle contraction via the regulation of the release of sequestered calcium ion by sarcoplasmic reticulum into cytosol. The sarcoplasmic reticulum is the endoplasmic reticulum of striated muscle, specialised for the sequestration of calcium ions that are released upon receipt of a signal relayed by the T tubules from the neuromuscular junction.


negative regulation of calcium ion transport

Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of calcium ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


regulation of calcium ion import across plasma membrane

Any process that modulates the frequency, rate or extent of calcium ion import across plasma membrane.


regulation of calcium ion transmembrane transport via high voltage-gated calcium channel

Any process that modulates the frequency, rate or extent of generation of calcium ion transmembrane transport via high voltage-gated calcium channel.


positive regulation of calcium ion import

Any process that increases the rate, frequency, or extent of the directed movement of calcium ions into a cell or organelle.


regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum

Any process that modulates the rate, frequency or extent of release of sequestered calcium ion into cytosol by the sarcoplasmic reticulum, the process in which the release of sequestered calcium ion by sarcoplasmic reticulum into cytosol occurs via calcium release channels.


negative regulation of calcium ion import into sarcoplasmic reticulum

Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion import into sarcoplasmic reticulum.


positive regulation of calcium ion transport into cytosol

Any process that increases the rate of the directed movement of calcium ions into the cytosol of a cell. The cytosol is that part of the cytoplasm that does not contain membranous or particulate subcellular components.


negative regulation of store-operated calcium entry

Any process that stops, prevents or reduces the frequency, rate or extent of store-operated calcium entry.


positive regulation of calcium ion import across plasma membrane

Any process that activates or increases the frequency, rate or extent of calcium ion import across plasma membrane.


negative regulation of calcium ion import

Any process that decreases the rate, frequency, or extent of the directed movement of calcium ions into a cell or organelle.


positive regulation of calcium ion transmembrane transport

Any process that activates or increases the frequency, rate or extent of calcium ion transmembrane transport.


positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel

Any process that activates or increases the frequency, rate or extent of calcium ion transmembrane transport via high voltage-gated calcium channel.


regulation of calcium import into the mitochondrion

Any process that modulates the frequency, rate or extent of calcium import into the mitochondrion.


negative regulation of calcium ion transport into cytosol

Any process that decreases the rate of the directed movement of calcium ions into the cytosol of a cell. The cytosol is that part of the cytoplasm that does not contain membranous or particulate subcellular components.


positive regulation of calcium ion transport

Any process that activates or increases the frequency, rate or extent of the directed movement of calcium ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


positive regulation of release of sequestered calcium ion into cytosol

Any process that activates or increases the frequency, rate or extent of the release into the cytosolic compartment of calcium ions sequestered in the endoplasmic reticulum or mitochondria.


positive regulation of calcium ion transport into cytosol involved in cellular response to calcium ion

Any positive regulation of calcium ion transport into cytosol that is involved in cellular response to calcium ion.


negative regulation of calcium ion transmembrane transport via high voltage-gated calcium channel

Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion transmembrane transport via high voltage-gated calcium channel.


negative regulation of calcium ion transmembrane transport

Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion transmembrane transport.


regulation of calcium ion export across plasma membrane

Any process that modulates the frequency, rate or extent of calcium ion export across the plasma membrane.


negative regulation of calcium ion transport into cytosol involved in cellular response to salt stress

Any negative regulation of calcium ion transport into cytosol that is involved in cellular response to salt stress.


positive regulation of calcium import into the mitochondrion

Any process that activates or increases the frequency, rate or extent of calcium import into the mitochondrion.


regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion

Any process that modulates the frequency, rate or extent of cardiac muscle contraction via the regulation of the release of sequestered calcium ion by sarcoplasmic reticulum into cytosol. The sarcoplasmic reticulum is the endoplasmic reticulum of striated muscle, specialised for the sequestration of calcium ions that are released upon receipt of a signal relayed by the T tubules from the neuromuscular junction.


regulation of calcium ion import

Any process that modulates the rate, frequency, or extent of the directed movement of calcium ions into a cell or organelle.


negative regulation of calcium ion export across plasma membrane

Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion export across the plasma membrane.


regulation of calcium ion transport into cytosol

Any process that modulates the rate of the directed movement of calcium ions into the cytosol of a cell. The cytosol is that part of the cytoplasm that does not contain membranous or particulate subcellular components.


regulation of calcium ion import into sarcoplasmic reticulum

Any process that modulates the frequency, rate or extent of calcium ion import into sarcoplasmic reticulum.


negative regulation of release of sequestered calcium ion into cytosol

Any process that stops, prevents, or reduces the frequency, rate or extent of the release into the cytosolic compartment of calcium ions sequestered in the endoplasmic reticulum or mitochondria.


positive regulation of calcium ion export across plasma membrane

Any process that activates or increases the frequency, rate or extent of calcium ion export across the plasma membrane.


positive regulation of store-operated calcium entry

Any process that activates or increases the frequency, rate or extent of store-operated calcium entry.


regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion

Any process that modulates the frequency, rate or extent of skeletal muscle contraction via the regulation of the release of sequestered calcium ion by sarcoplasmic reticulum into cytosol. The sarcoplasmic reticulum is the endoplasmic reticulum of striated muscle, specialised for the sequestration of calcium ions that are released upon receipt of a signal relayed by the T tubules from the neuromuscular junction.


regulation of calcium ion transmembrane transport

Any process that modulates the frequency, rate or extent of calcium ion transmembrane transport.


negative regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion

Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle contraction via the regulation of the release of sequestered calcium ion by sarcoplasmic reticulum into cytosol. The sarcoplasmic reticulum is the endoplasmic reticulum of striated muscle, specialised for the sequestration of calcium ions that are released upon receipt of a signal relayed by the T tubules from the neuromuscular junction.


positive regulation of calcium ion import into sarcoplasmic reticulum

Any process that activates or increases the frequency, rate or extent of calcium ion import into sarcoplasmic reticulum.


negative regulation of calcium ion import across plasma membrane

Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion import across plasma membrane.


positive regulation of fast-twitch skeletal muscle fiber contraction

Any process that activates or increases the frequency, rate or extent of fast-twitch skeletal muscle contraction.


regulation of fast-twitch skeletal muscle fiber contraction

Any process that modulates the frequency, rate or extent of fast-twitch skeletal muscle contraction.


negative regulation of fast-twitch skeletal muscle fiber contraction

Any process that stops, prevents, or reduces the frequency, rate or extent of fast-twitch skeletal muscle contraction.


larval development

The process whose specific outcome is the progression of the larva over time, from its formation to the mature structure. The larva is the early, immature form of an that at birth or hatching is fundamentally unlike its parent and must metamorphose before assuming the adult characters.


amphibian larval development

The process whose specific outcome is the progression of the amphibian larva over time, from its formation to the mature structure. Amphibian larvae, sometimes called pollywogs or tadpoles, hatch from eggs and begin to grow limbs and other adult physical features at various times, depending on the species, before they metamorphose into the adult form.


instar larval development

The process whose specific outcome is the progression of the larva over time, from its formation to the mature structure. This begins with the newly hatched first-instar larva, through its maturation to the end of the last larval stage. An example of this process is found in Drosophila melanogaster.


dauer larval development

The process whose specific outcome is the progression of the dauer larva over time, through the facultative diapause of the dauer (enduring) larval stage, with specialized traits adapted for dispersal and long-term survival, with elevated stress resistance and without feeding.


nematode larval development

The process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew.


lysine 2-monooxygenase activity

Catalysis of the reaction: L-lysine + O2 = 5-aminopentanamide + CO2 + H2O.


benzylpenicillin catabolic process

The chemical reactions and pathways resulting in the breakdown of benzylpenicillin.


antibiotic catabolic process

The chemical reactions and pathways resulting in the breakdown of antibiotic, a substance produced by or derived from certain fungi, bacteria, and other organisms, that can destroy or inhibit the growth of other microorganisms.


beta-lactam antibiotic catabolic process

The chemical reactions and pathways resulting in the breakdown of a beta-lactam antibiotic, any member of a class of natural or semisynthetic antibiotics whose characteristic feature is a strained, four-membered beta-lactam ring. They include the penicillins and many of the cephalosporins.


penicillin catabolic process

The chemical reactions and pathways resulting in the breakdown of any antibiotic that contains the condensed beta-lactamthiazolidine ring system.


bacteriocin catabolic process

The chemical reactions and pathways resulting in the breakdown of a bacteriocin, any of a heterogeneous group of polypeptide antibiotics that are secreted by certain bacterial strains and are able to kill cells of other susceptible (frequently related) strains after adsorption at specific receptors on the cell surface. They include the colicins, and their mechanisms of action vary.


exogenous antibiotic catabolic process

The chemical reactions and pathways resulting in the breakdown of an antibiotic that has originated externally to the cell or organism.


endogenous antibiotic catabolic process

The chemical reactions and pathways resulting in the breakdown of an antibiotic that has originated internally within the cell or organism.


cephamycin C catabolic process

The chemical reactions and pathways resulting in the breakdown of cephamycin C.


peptide antibiotic catabolic process

The chemical reactions and pathways resulting in the breakdown of peptides with antibiotic activity.


cytoplasm protein quality control by the ubiquitin-proteasome system

The chemical reactions and pathways resulting in the breakdown of misfolded proteins in the cytoplasm, which are targeted to cytoplasmic proteasomes for degradation.


negative regulation of catalase activity

Any process that stops, prevents or reduces the frequency, rate or extent of catalase activity.


L-methionine salvage from methionine sulphoxide

The generation of L-methionine from methionine sulphoxide.


amino acid salvage

Any process which produces an amino acid from derivatives of it, without de novo synthesis.


L-methionine salvage from S-adenosylmethionine

The chemical reactions and pathways resulting in the formation of L-methionine from S-adenosylmethionine.


L-methionine salvage

Any process that generates L-methionine from derivatives of it, without de novo synthesis.


L-methionine salvage from methylthioadenosine

The generation of L-methionine (2-amino-4-(methylthio)butanoic acid) from methylthioadenosine.


protein insertion into ER membrane by N-terminal cleaved signal sequence

A process of protein insertion into the endoplasmic reticulum (ER) membrane in which N-terminal cleaved signal sequences direct polypeptides to the ER.


regulation of kidney development

Any process that modulates the rate, frequency or extent of kidney development. Kidney development is the process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine.


positive regulation of ureteric bud formation

Any process that increases the rate or extent of the developmental process pertaining to the initial formation of the ureteric bud from the Wolffian duct.


positive regulation of branching involved in ureteric bud morphogenesis

Any process that increases the rate, frequency or extent of branching involved in ureteric bud morphogenesis, the process in which the branching structure of the ureteric bud is generated and organized. The ureteric bud is an epithelial tube that grows out from the metanephric duct. The bud elongates and branches to give rise to the ureter and kidney collecting tubules.


regulation of mesonephros development

Any process that modulates the rate, frequency or extent of mesonephros development. Mesonephros development is the process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. The mesonephros is an endocrine and metabolic organ that filters the blood and excretes the end products of body metabolism in the form of urine.


renal vesicle induction

Signaling at short range between cells of the ureteric bud terminus and the kidney mesenchyme that positively regulates the formation of the renal vesicle.


regulation of ureteric bud formation

Any process that modulates the developmental process pertaining to the initial formation of the ureteric bud from the Wolffian duct.


negative regulation of mesonephros development

Any process that decreases the rate, frequency or extent of mesonephros development. Mesonephros development is the process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. The mesonephros is an organ that filters the blood and excretes the end products of body metabolism in the form of urine.


negative regulation of metanephros development

Any process that decreases the rate, frequency or extent of metanephros development. Metanephros development is the process whose specific outcome is the progression of the metanephros over time, from its formation to the mature structure. The metanephros is an organ that filters the blood and excretes the end products of body metabolism in the form of urine.


negative regulation of metanephric ureteric bud development

Any process that stops, prevents or reduces the frequency, rate or extent of metanephric ureteric bud development.


positive regulation of kidney development

Any process that increases the rate, frequency or extent of kidney development. Kidney development is the process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine.


positive regulation of metanephric ureteric bud development

Any process that activates or increases the frequency, rate or extent of metanephric ureteric bud development.


regulation of metanephros development

Any process that modulates the rate, frequency or extent of metanephros development. Metanephros development is the process whose specific outcome is the progression of the metanephros over time, from its formation to the mature structure. The metanephros is an endocrine and metabolic organ that filters the blood and excretes the end products of body metabolism in the form of urine.


negative regulation of branching involved in ureteric bud morphogenesis

Any process that decreases the rate, frequency or extent of branching involved in ureteric bud morphogenesis, the process in which the branching structure of the ureteric bud is generated and organized. The ureteric bud is an epithelial tube that grows out from the metanephric duct. The bud elongates and branches to give rise to the ureter and kidney collecting tubules.


regulation of branching involved in ureteric bud morphogenesis

Any process that modulates the rate, frequency or extent of branching involved in ureteric bud morphogenesis, the process in which the branching structure of the ureteric bud is generated and organized. The ureteric bud is an epithelial tube that grows out from the metanephric duct. The bud elongates and branches to give rise to the ureter and kidney collecting tubules.


positive regulation of metanephros development

Any process that increases the rate, frequency or extent of metanephros development. Metanephros development is the process whose specific outcome is the progression of the metanephros over time, from its formation to the mature structure. The metanephros is an organ that filters the blood and excretes the end products of body metabolism in the form of urine.


regulation of metanephric ureteric bud development

Any process that modulates the frequency, rate or extent of metanephric ureteric bud development.


metanephric renal vesicle induction

Signaling at short range between cells of the ureteric bud terminus and the kidney mesenchyme that positively regulates the formation of the metanephric renal vesicle.


negative regulation of metanephric mesenchymal cell migration

Any process that stops, prevents or reduces the frequency, rate or extent of metanephric mesenchymal cell migration.


negative regulation of kidney development

Any process that decreases the rate, frequency or extent of kidney development. Kidney development is the process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine.


mesonephric renal vesicle induction

Signaling at short range between cells of the ureteric bud terminus and the kidney mesenchyme that positively regulates the formation of the mesonephric renal vesicle.


positive regulation of mesonephros development

Any process that increases the rate, frequency or extent of mesonephros development. Mesonephros development is the process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. The mesonephros is an organ that filters the blood and excretes the end products of body metabolism in the form of urine.


tendon development

The process whose specific outcome is the progression of a tendon over time, from its formation to the mature structure. A tendon is a fibrous, strong, connective tissue that connects muscle to bone or integument and is capable of withstanding tension. Tendons and muscles work together to exert a pulling force.


connective tissue development

The progression of a connective tissue over time, from its formation to the mature structure.


growth plate cartilage development

The process whose specific outcome is the progression of the cartilage that will provide a scaffold for mineralization of endochondral bones as they elongate or grow.


fat pad development

The progression of a fat pad from its initial formation to its mature structure. A fat pad is an accumulation of adipose tissue.


adipose tissue development

The process whose specific outcome is the progression of adipose tissue over time, from its formation to the mature structure. Adipose tissue is specialized tissue that is used to store fat.


metanephric glomerular mesangium development

The process whose specific outcome is the progression of the metanephric glomerular mesangium over time, from its formation to the mature structure. The metanephric glomerular mesangium is the thin membrane connective tissue composed of mesangial cells in the metanephros, which helps to support the capillary loops in a renal glomerulus.


lung connective tissue development

The biological process whose specific outcome is the progression of lung connective tissue from an initial condition to its mature state. This process begins with the formation of lung connective tissue and ends with the mature structure. The lung connective tissue is a material made up of fibers forming a framework and support structure for the lungs.


mammary gland fat development

The progression of the mammary gland fat over time, from its formation to the mature structure. The mammary fat is an adipose structure in the gland that is invaded by the mammary ducts.


mesonephric capsule development

The progression of the mesonephric capsule over time, from its formation to the mature structure. The mesonephric capsule is the tough fibrous layer surrounding the mesonephros, covered in a thick layer of perinephric adipose tissue.


tendon sheath development

The process whose specific outcome is the progression of a tendon sheath over time, from its formation to the mature structure. A tendon sheath is a layer of membrane around a tendon. It permits the tendon to move.


cardiac skeleton development

The progression of the cardiac skeleton over time, from its formation to the mature structure. The cardiac skeleton is a specialized extracellular matrix that separates the atria from the ventricles and provides physical support for the heart.


kidney stroma development

The process whose specific outcome is the progression of the kidney stroma over time, from its formation to the mature structure. The kidney stroma is the mesenchyme of the mature kidney.


mesonephric glomerular mesangium development

The process whose specific outcome is the progression of the mesonephric glomerular mesangium over time, from its formation to the mature structure. The mesonephric glomerular mesangium is the thin membrane connective tissue composed of mesangial cells in the mesonephros, which helps to support the capillary loops in a renal glomerulus.


metanephric capsule development

The process whose specific outcome is the progression of the metanephric capsule over time, from its formation to the mature structure. The metanephric capsule is the tough fibrous layer surrounding the metanephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage.


glomerular mesangium development

The process whose specific outcome is the progression of the glomerular mesangium over time, from its formation to the mature structure. The glomerular mesangium is the thin membrane connective tissue composed of mesangial cells, which helps to support the capillary loops in a renal glomerulus.


renal capsule development

The process whose specific outcome is the progression of the renal capsule over time, from its formation to the mature structure. The renal capsule is the tough fibrous layer surrounding the kidney, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage. During development, it comprises a single layer of flattened cells that lie just above the cortical stroma and the condensed mesenchyme of the nephrogenic zone. It is in this region that the early stages of nephron induction and formation of new generations ureteric bud branches occur, as the kidney expands.


7-methylguanosine biosynthetic process

The chemical reactions and pathways resulting in the formation of 7-methylguanosine, a modified nucleoside that forms a cap at the 5'-terminus of eukaryotic mRNA.


protein C inhibitor-plasma kallikrein complex

biolink:CellularComponent biolink:AnatomicalEntity biolink:OrganismalEntity biolink:BiologicalEntity biolink:NamedThing biolink:PhysicalEssence biolink:SubjectOfInvestigation biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

A heterodimeric protein complex that contains protein C inhibitor (SERPINA5) and plasma kallikrein (KLK1B); formation of the complex inhibits the serine protease activity of plasma kallikrein.


bundle sheath cell differentiation

The process in which a relatively unspecialized cell acquires the specialized features of a bundle sheath cell.


o-xylene catabolic process

The chemical reactions and pathways resulting in the breakdown of o-xylene, (1,2-dimethylbenzene) a colorless, liquid aromatic hydrocarbon.


xylene catabolic process

The chemical reactions and pathways resulting in the breakdown of xylene, a mixture of three colorless, aromatic hydrocarbon liquids, ortho-, meta- and para-xylene.


m-xylene catabolic process

The chemical reactions and pathways resulting in the breakdown of m-xylene, 1,3-dimethylbenzene, a colorless, liquid aromatic hydrocarbon.


p-xylene catabolic process

The chemical reactions and pathways resulting in the breakdown of p-xylene (1,4-dimethylbenzene), a colorless, liquid aromatic hydrocarbon.


4-chlorobenzoate-CoA ligase activity

Catalysis of the reaction: 4-chlorobenzoate + CoA + ATP = 4-chlorobenzoyl-CoA + AMP + diphosphate. This reaction requires magnesium and is part of the bacterial 2,4-dichlorobenzoate degradation pathway.


(+)-abscisic acid D-glucopyranosyl ester transmembrane transporter activity

Enables the transfer of (+)-abscisic acid D-glucopyranosyl ester from one side of a membrane to the other.


auditory receptor cell stereocilium organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a stereocilium. A stereocilium is an actin-based protrusion from the apical surface of auditory hair cells.


alpha7-beta1 integrin-focal adhesion kinase complex

A protein complex that consists of an alpha7-beta1 integrin complex bound to focal adhesion kinase.


The oxidative deamination of N-terminal peptidyl-cysteine to form pyruvic acid with an amide bond between its 1-carboxyl group and the N-terminal residue.


N-terminal protein amino acid deamination

The removal of an amino group from the N-terminal amino acid residue of a protein.


N-terminal peptidyl-valine deamination

The deamination of the N-terminal valine residue of a protein to form isobutyrate.


The removal of an amino group from the side chain of an N-terminal asparagine residue of a protein.


The removal of an amino group from the side chain of an N-terminal glutamine residue of a protein.


N-terminal peptidyl-amino acid deamination to pyruvic acid

The oxidative deamination of N-terminal peptidyl-cysteine, or peptidyl-serine, to form pyruvic acid with an amide bond between its 1-carboxyl group and the N-terminal residue.


The deamination of N-terminal peptidyl-threonine to form peptidyl-2-oxobutanoic acid.


N-terminal protein amino acid deamination, from amino carbon

The oxidative deamination of the alpha carbon of an encoded N-terminal amino acid, to form pyruvic acid retaining an amide bond between its 1-carboxyl group and the adjacent residue. The pyruvate 2-oxo group may become an enzyme active site, or it may be reduced to an alcohol.


N-terminal protein amino acid deamination, from side chain

The removal of an amino group from the side chain of an N-terminal asparagine or glutamine residue of a protein.


N-terminal peptidyl-serine deamination

The oxidative deamination of N-terminal peptidyl-serine to form pyruvic acid with an amide bond between its 1-carboxyl group and the N-terminal residue.


positive regulation of adaptive immune memory response

Any process that activates or increases the frequency, rate or extent of adaptive immune memory response.


biotin-[propionyl-CoA-carboxylase (ATP-hydrolyzing)] ligase activity

Catalysis of the reaction: ATP + biotin + apo-(propanoyl-CoA:carbon-dioxide ligase (ADP-forming)) = AMP + diphosphate + (propanoyl-CoA:carbon-dioxide ligase (ADP-forming)).


medium-term memory

The memory process that deals with the storage, retrieval and modification of information received at a time ago that is intermediate between that of short and long term memory (30min - 7hrs in Drosophila melanogaster).


outer membrane-bounded periplasmic space

The region between the inner (cytoplasmic or plasma) membrane and outer membrane of organisms with two membranes such as Gram negative bacteria. These periplasmic spaces are relatively thick and contain a thin peptidoglycan layer (PGL), also referred to as a thin cell wall.


cellular response to temperature stimulus

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a temperature stimulus.


F-9775B biosynthetic process

The chemical reactions and pathways resulting in the formation of F-9775B.


glutathione specific gamma-glutamylcyclotransferase activity

Catalysis of the reaction: glutathione = 5-oxoproline + L-cysteinylglycine.


narrow pore channel activity

Enables the transport of a solute across a membrane via a narrow pore channel that may be gated or ungated.


narrow pore, gated channel activity

Enables the transport of a solute across a membrane via a narrow pore channel that opens in response to a particular stimulus.


leak channel activity

Enables the transport of a solute across a membrane via a narrow pore channel that is open even in an unstimulated or 'resting' state.


Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: raffinose(out) + H+(out) = raffinose(in) + H+(in).


raffinose transmembrane transporter activity

Enables the transfer of raffinose from one side of a membrane to the other. Raffinose occurs in plants almost as commonly as sucrose and is present in cereal grains, cotton seeds, and many legumes. It is synthesized from sucrose by transfer of a galactopyranoside from myo-inositol.


lactose catabolic process via tagatose-6-phosphate

The chemical reactions and pathways resulting in the breakdown of lactose, via the intermediate tagatose-6-phosphate.


oligosaccharide metabolic process

The chemical reactions and pathways involving oligosaccharides, molecules with between two and (about) 20 monosaccharide residues connected by glycosidic linkages.


sucrose catabolic process

The chemical reactions and pathways resulting in the breakdown of sucrose, the disaccharide fructofuranosyl-glucopyranoside.


ajugose biosynthetic process

The chemical reactions and pathways resulting in the formation of ajugose, the hexasaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside.


lipopolysaccharide core region metabolic process

The chemical reactions and pathways resulting in the formation of the core region of bacterial lipopolysaccharides, which contains ten saccharide residues. The structure of this core oligosaccharide appears to be similar in closely related bacterial strains.


maltose metabolic process

The chemical reactions and pathways involving the disaccharide maltose (4-O-alpha-D-glucopyranosyl-D-glucopyranose), an intermediate in the catabolism of glycogen and starch.


lactose catabolic process via UDP-galactose

The chemical reactions and pathways resulting in the breakdown of lactose, via the intermediate UDP-galactose.


cellotriose metabolic process

The chemical reactions and pathways involving a cellotriose.


trehalose metabolism in response to heat stress

The chemical reactions and pathways involving trehalose that occur as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.


trehalose catabolism in response to heat stress

The chemical reactions and pathways resulting in the degradation of trehalose that occur as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.


melibiose catabolic process

The chemical reactions and pathways resulting in the breakdown of melibiose, the disaccharide 6-O-alpha-D-galactopyranosyl-D-glucose.


trehalose biosynthesis in response to heat stress

The chemical reactions and pathways resulting in the formation of trehalose that occur as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.


verbascose metabolic process

The chemical reactions and pathways involving verbascose, the pentasaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside.


stachyose metabolic process

The chemical reactions and pathways involving stachyose, the tetrasaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside.


sucrose catabolic process via 3'-ketosucrose

The chemical reactions and pathways resulting in the breakdown of sucrose, which proceeds via the conversion of sucrose to 3'-ketosucrose. 3'-ketosucrose is hydrolyzed to 3-ketoglucose and fructose, and the 3-ketoglucose is then be converted to glucose.


raffinose family oligosaccharide biosynthetic process

The chemical reactions and pathways resulting in the formation of raffinose family oligosaccharides (RFOs, such as raffinose, stachyose, verbascose and other molecules with a higher degree of galactosyl polymerization).


trehalose catabolic process

The chemical reactions and pathways resulting in the breakdown of trehalose, a disaccharide isomeric with sucrose and obtained from certain lichens and fungi.


verbascose biosynthetic process

The chemical reactions and pathways resulting in the formation of verbascose, the pentasaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside.


lipopolysaccharide core region biosynthetic process

The chemical reactions and pathways resulting in the formation of the core region of bacterial lipopolysaccharides, which contains ten saccharide residues.


cellodextrin metabolic process

The chemical reactions and pathways involving a cellodextrin.


melibiose biosynthetic process

The chemical reactions and pathways resulting in the formation of melibiose, the disaccharide 6-O-alpha-D-galactopyranosyl-D-glucose.


sucrose catabolic process to fructose-6-phosphate through glucose and fructose

The chemical reactions and pathways resulting in the breakdown of sucrose, to yield fructose-6-phosphate through both glucose and fructose intermediates.


disaccharide catabolic process

The chemical reactions and pathways resulting in the breakdown of disaccharides, sugars composed of two monosaccharide units.


oligosaccharide catabolic process

The chemical reactions and pathways resulting in the breakdown of oligosaccharides, molecules with between two and (about) 20 monosaccharide residues connected by glycosidic linkages.


trehalose metabolism in response to cold stress

The chemical reactions and pathways involving trehalose that occur as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism.


stachyose biosynthetic process

The chemical reactions and pathways resulting in the formation of stachyose, the tetrasaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside.


sucrose biosynthetic process

The chemical reactions and pathways resulting in the formation of sucrose, the disaccharide fructofuranosyl-glucopyranoside.


cyclodextrin metabolic process

The chemical reactions and pathways involving a cyclodextrin.


cyclodextrin catabolic process

The chemical reactions and pathways resulting in the breakdown of a cyclodextrin.


lactose catabolic process

The chemical reactions and pathways resulting in the breakdown of lactose, the disaccharide galactopyranosyl-glucose.


maltoheptaose catabolic process

The chemical reactions and pathways resulting in the breakdown of a maltoheptaose.


lactose biosynthetic process

The chemical reactions and pathways resulting in the formation of lactose, the disaccharide galactopyranosyl-glucose.


ajugose biosynthetic process using galactinol:raffinose galactosyltransferase

The chemical reactions and pathways resulting in the formation of ajugose, the hexasaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside, by a pathway in which galactinol:raffinose galactosyltransferase catalyzes chain elongation by transferring the alpha-galactosyl residue of galactinol to the oligosaccharide.


disaccharide biosynthetic process

The chemical reactions and pathways resulting in the formation of disaccharides, sugars composed of two monosaccharide units.


disaccharide metabolic process

The chemical reactions and pathways involving any disaccharide, sugars composed of two monosaccharide units.


cellobiose metabolic process

The chemical reactions and pathways involving a cellobiose.


raffinose biosynthetic process

The chemical reactions and pathways resulting in the formation of raffinose, the trisaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside.


raffinose catabolic process

The chemical reactions and pathways resulting in the breakdown of raffinose, the trisaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside.


The chemical reactions and pathways resulting in the formation of 6-alpha-maltosylglucose, also known as isopanose.


The chemical reactions and pathways involving 6-alpha-maltosylglucose, also known as isopanose.


maltoheptaose metabolic process

The chemical reactions and pathways involving a maltoheptaose.


lactose metabolic process

The chemical reactions and pathways involving lactose, the disaccharide galactopyranosyl-glucose.


maltose biosynthetic process

The chemical reactions and pathways resulting in the formation of the disaccharide maltose (4-O-alpha-D-glucopyranosyl-D-glucopyranose).


cellotriose catabolic process

The chemical reactions and pathways resulting in the breakdown of a cellotriose.


cellooligosaccharide metabolic process

The chemical reactions and pathways involving a cellooligosaccharide.


sucrose metabolic process

The chemical reactions and pathways involving sucrose, the disaccharide fructofuranosyl-glucopyranoside.


cellooligosaccharide catabolic process

The chemical reactions and pathways resulting in the breakdown of a cellooligosaccharide.


cellobiose catabolic process

The chemical reactions and pathways resulting in the breakdown of a cellobiose.


trehalose biosynthetic process

The chemical reactions and pathways resulting in the formation of trehalose, a disaccharide isomeric with sucrose and obtained from certain lichens and fungi.


raffinose metabolic process

The chemical reactions and pathways involving raffinose, the trisaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside.


ajugose biosynthetic process using galactan:galactan galactosyltransferase

The chemical reactions and pathways resulting in the formation of ajugose, the hexasaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside, by a pathway in which galactan:galactan galactosyltransferase catalyzes chain elongation by transferring the alpha-galactosyl residue of one raffinose-family oligosaccharide to another.


trehalose metabolism in response to stress

The chemical reactions and pathways involving trehalose that occur as a result of a stimulus indicating the organism is under stress.


trehalose metabolism in response to water deprivation

The chemical reactions and pathways involving trehalose that occur as a result of deprivation of water.


lactose catabolic process, using glucoside 3-dehydrogenase

The chemical reactions and pathways resulting in the breakdown of lactose, catalyzed by the enzyme glucoside 3-dehydrogenase.


maltose catabolic process

The chemical reactions and pathways resulting in the breakdown of the disaccharide maltose (4-O-alpha-D-glucopyranosyl-D-glucopyranose).


cellodextrin catabolic process

The chemical reactions and pathways resulting in the breakdown of a cellodextrin.


melibiose metabolic process

The chemical reactions and pathways involving melibiose, the disaccharide 6-O-alpha-D-galactopyranosyl-D-glucose.


aerobic raffinose catabolic process

The chemical reactions and pathways resulting in the breakdown of raffinose that occur in the presence of oxygen.


ajugose metabolic process

The chemical reactions and pathways involving ajugose, the hexasaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside.


The chemical reactions and pathways resulting in the breakdown of 6-alpha-maltosylglucose, also known as isopanose.


trehalose metabolic process

The chemical reactions and pathways involving trehalose, a disaccharide isomeric with sucrose and obtained from certain lichens and fungi.


sucrose catabolic process to fructose-6-phosphate and glucose-6-phosphate

The chemical reactions and pathways resulting in the breakdown of sucrose, which proceeds by phosphorylation of sucrose to form sucrose-6-phosphate. The subsequent actions of a hydrolase and a fructokinase generate fructose-6-phosphate and glucose-6-phosphate.


renal zinc excretion

The elimination of zinc ions from peritubular capillaries (or surrounding hemolymph in invertebrates) into the renal tubules to be incorporated subsequently into the urine.


lysophagy

The selective autophagy process in which a damaged lysosome is degraded by macroautophagy.


glycophagy

The selective autophagy process in which cellular glycogen is delivered to the vacuole and degraded in response to changing cellular conditions.


ribophagy

The selective autophagy process in which cells degrade mature ribosomes under conditions of starvation.


micromitophagy

Degradation of a mitochondrion by lysosomal microautophagy.


mitophagy by induced vacuole formation

The process in which cells degrade mitochondria by inducing a vacuole-like structure which directly engulfs and degrades the unhealthy mitochondria by accumulating lysosomes.


xenophagy

The selective autophagy process in which a region of cytoplasm containing an intracellular pathogen or some part of an intracellular pathogen (e.g. viral capsid) is enclosed in a double membrane bound autophagosome, which then fuses with the lysosome leading to degradation of the contents.


micropexophagy

Degradation of a peroxisome by lysosomal microautophagy.


proteaphagy

The selective autophagy process that clears 26S proteasomes; homeostatic mechanism within the ubiquitin system that modulates proteolytic capacity and eliminates damaged particles.


autophagy of peroxisome

The process in which peroxisomes are delivered to a type of vacuole and degraded in response to changing nutrient conditions.


pexophagy

The selective autophagy process in which a peroxisome is degraded by macroautophagy.


mitophagy

The selective autophagy process in which a mitochondrion is degraded by macroautophagy.


reticulophagy

The selective autohagy process in which parts of the endoplasmic reticulum are loaded into autophagosomes, delivered to the vacuole, and degraded in response to changing cellular conditions.


aggrephagy

Selective degradation of protein aggregates by macroautophagy.


lipophagy

The selective autophagy process in which lipid droplets are delivered to the vacuole and degraded in response to changing cellular conditions.


chaperone-mediated autophagy

The autophagy process which begins when chaperones and co-chaperones recognize a target motif and unfold the substrate protein. The proteins are then transported to the lysosome where they are degraded.


microlipophagy

Microautophagy-mediated direct internalization of lipid droplets into a lysosome-like vacuole during nutrient depletion, such as during the transition to stationary phase or in response to nutrient limitation. Microlipophagy is mediated by the formation of sterol-enriched vacuolar microdomains at sites of engulfment. Initiation of microautophagy is defined as the point where liquid-ordered microdomains are formed at sites of engulfment, that requires S. cerevisiae Atg32p and Atg21p, as well as Niemann-Pick type C (NPC) sterol transporter proteins, Ncr1p and Npc2p. This is followed by redistribution of Atg14p from ER exit sites onto liquid-ordered vacuole membrane domains through interaction with stabilized AMP-activated protein kinase (AMPK), and together with Atg6p facilities docking and internalization of lipid droplets (LDs) at sites of invagination.


late endosomal microautophagy

The autophagy process by which cytosolic proteins targeted for degradation are tagged with a chaperone and are directly transferred into and degraded in a late endosomal compartment.


SRP-dependent cotranslational protein targeting to membrane, docking

The process in which an SRP-bound ribosome forms a complex with the SRP receptor in the ER membrane, allowing the ribosome to bind to the membrane, during cotranslational membrane targeting.


DL-2 haloacid dehalogenase activity

Catalysis of the reaction: trichloroacetate + 2 H2O = 3 H+ + 3 Cl- + oxalate.


positive regulation of T-helper 17 cell lineage commitment

Any process that activates or increases the frequency, rate or extent of T-helper 17 cell lineage commitment.


granulocyte macrophage colony-stimulating factor production

The appearance of granulocyte macrophage colony-stimulating factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


lysine biosynthetic process via diaminopimelate and N-succinyl-2-amino-6-ketopimelate

The chemical reactions and pathways resulting in the formation of lysine, via the intermediates diaminopimelate and N-succinyl-2-amino-6-ketopimelate; in this pathway tetrahydrodipicolinate is converted to meso-diaminopimelate in four enzymatic steps.


cranial ganglion maturation

A developmental process, independent of morphogenetic (shape) change, that is required for a cranial ganglion to attain its fully functional state.


ganglion maturation

A developmental process, independent of morphogenetic (shape) change, that is required for ganglion to attain its fully functional state.


trigeminal ganglion maturation

A developmental process, independent of morphogenetic (shape) change, that is required for a trigeminal ganglion to attain its fully functional state.


Catalysis of the reaction: a 6-methoxy-3-methyl-2-all-trans-polyprenyl-1,4-benzoquinol + AH2 + O2 = A + a 3-demethylubiquinol + H2O.


negative regulation of Wnt signaling pathway involved in heart development

Any process that decreases the rate, frequency, or extent of the series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell, resulting a change in cell state that contributes to the progression of the heart over time.


negative regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment

Any process that stops, prevents or reduces the frequency, rate or extent of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment.


positive regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion

Any process that increases the frequency, rate or extent of pheromone-dependent signal transduction during conjugation with cellular fusion, a signal transduction process resulting in the relay, amplification or dampening of a signal generated in response to pheromone exposure in organisms that undergo conjugation with cellular fusion.


regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion

Any process that modulates the frequency, rate or extent of pheromone-dependent signal transduction during conjugation with cellular fusion, a signal transduction process resulting in the relay, amplification or dampening of a signal generated in response to pheromone exposure in organisms that undergo conjugation with cellular fusion.


negative regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion

Any process that decreases the frequency, rate or extent of pheromone-dependent signal transduction during conjugation with cellular fusion, a signal transduction process resulting in the relay, amplification or dampening of a signal generated in response to pheromone exposure in organisms that undergo conjugation with cellular fusion.


Catalysis of the reaction: gamma-aminovinylacetate + H2O = succinic semialdehyde + NH3.


vitamin D biosynthetic process

The chemical reactions and pathways resulting in the formation of vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism. Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3).


vitamin biosynthetic process

The chemical reactions and pathways resulting in the formation of a vitamin, one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body.


vitamin D3 biosynthetic process

The chemical reactions and pathways resulting in the formation of vitamin D3.


phylloquinone biosynthetic process

The chemical reactions and pathways resulting in the formation of phylloquinone, vitamin K1, a quinone-derived compound synthesized by green plants.


aerobic cobalamin biosynthetic process

The chemical reactions and pathways resulting in the formation of cobalamin (vitamin B12) in the presence of oxygen.


L-ascorbic acid biosynthetic process

The chemical reactions and pathways resulting in the formation of L-ascorbic acid; L-ascorbic acid ionizes to give L-ascorbate, (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate, which is required as a cofactor in the oxidation of prolyl residues to hydroxyprolyl, and other reactions.


vitamin E biosynthetic process

The chemical reactions and pathways resulting in the formation of vitamin E, tocopherol, which includes a series of eight structurally similar compounds. Alpha-tocopherol is the most active form in humans and is a powerful biological antioxidant.


'de novo' pyridoxal 5'-phosphate biosynthetic process

The chemical reactions and pathways resulting in the formation of pyridoxal 5'-phosphate, the active form of vitamin B6, from simpler components.


thiamine biosynthetic process

The chemical reactions and pathways resulting in the formation of thiamine (vitamin B1), a water soluble vitamin present in fresh vegetables and meats, especially liver.


vitamin A biosynthetic process

The chemical reactions and pathways resulting in the formation of any of the vitamin A compounds, retinol, retinal (retinaldehyde) and retinoic acid. Animals cannot synthesize vitamin A de novo, but form it through oxidative cleavage of carotenoids.


fat-soluble vitamin biosynthetic process

The chemical reactions and pathways resulting in the formation of any of a diverse group of vitamins that are soluble in organic solvents and relatively insoluble in water.


vitamin B6 biosynthetic process

The chemical reactions and pathways resulting in the formation of any of the vitamin B6 compounds; pyridoxal, pyridoxamine and pyridoxine and the active form, pyridoxal phosphate.


calcitriol biosynthetic process from calciol

Conversion of vitamin D3 from its largely inactive form (calciol, also called cholecalciferol) into a hormonally active form (calcitriol). Conversion requires 25-hydroxylation of calciol in the liver to form calcidiol, and subsequent 1,alpha-hydroxylation of calcidiol in the kidney to form calcitriol.


folic acid biosynthetic process

The chemical reactions and pathways resulting in the formation of folic acid, pteroylglutamic acid.


riboflavin biosynthetic process

The chemical reactions and pathways resulting in the formation of riboflavin (vitamin B2), the precursor for the coenzymes flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD).


anaerobic cobalamin biosynthetic process

The chemical reactions and pathways resulting in the formation of cobalamin (vitamin B12) in the absence of oxygen.


L-ascorbic acid biosynthetic process via GDP-alpha-D-mannose

The chemical reactions and pathways resulting in the formation of L-ascorbic acid via the intermediate GDP-alpha-D-mannose.


thiamine diphosphate biosynthetic process

The chemical reactions and pathways resulting in the formation of thiamine diphosphate, a derivative of thiamine (vitamin B1) which acts as a coenzyme in a range of processes including the Krebs cycle.


pyridoxal phosphate biosynthetic process from pyridoxamine

The chemical reactions and pathways resulting in the formation of pyridoxal phosphate, the active form of vitamin B6, from pyridoxamine.


L-ascorbic acid biosynthetic process via UDP-alpha-D-glucuronate

The chemical reactions and pathways resulting in the formation of L-ascorbic acid via the intermediate UDP-alpha-D-glucuronate.


water-soluble vitamin biosynthetic process

The chemical reactions and pathways resulting in the formation of any of a diverse group of vitamins that are soluble in water.


thiamine salvage

A process that generates thiamine (vitamin B1) from derivatives of it without de novo synthesis.


pyridoxal biosynthetic process

The chemical reactions and pathways resulting in the formation of 3-hydroxy-5-(hydroxymethyl)-2-methyl-4-pyridinecarboxaldehyde, one of the vitamin B6 compounds.


cobalamin biosynthetic process

The chemical reactions and pathways resulting in the formation of cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom.


pyridoxine biosynthetic process

The chemical reactions and pathways resulting in the formation of pyridoxine, 2-methyl-3-hydroxy-4,5-bis(hydroxymethyl)pyridine, one of the vitamin B6 compounds.


vitamin K biosynthetic process

The chemical reactions and pathways resulting in the formation of any of the forms of vitamin K, quinone-derived vitamins which are involved in the synthesis of blood-clotting factors in mammals.


pyridoxal phosphate biosynthetic process

The chemical reactions and pathways resulting in the formation of pyridoxal phosphate, pyridoxal phosphorylated at the hydroxymethyl group of C-5, the active form of vitamin B6.


pyridoxal 5'-phosphate salvage

Any process that generates pyridoxal 5'-phosphate, the active form of vitamin B6, from derivatives of it without de novo synthesis.


thiamine-containing compound biosynthetic process

The chemical reactions and pathways resulting in the formation of thiamine (vitamin B1), and related compounds.


zonula adherens maintenance

Maintaining the zonula adherens junction, the cell-cell adherens junction formed near the apex of epithelial cells.


adherens junction disassembly

The disaggregation of an adherens junction into its constituent components. An adherens junction is a cell-cell junction composed of the epithelial cadherin-catenin complex at which the cytoplasmic face of the plasma membrane is attached to actin filaments.


zonula adherens assembly

Assembly of the zonula adherens, a cell-cell adherens junction which forms a continuous belt near the apex of epithelial cells.


adherens junction maintenance

The maintenance of an adherens junction. An adherens junction is a cell-cell junction composed of the epithelial cadherin-catenin complex at which the cytoplasmic face of the plasma membrane is attached to actin filaments.


nephrocyte diaphragm assembly

The aggregation, arrangement and bonding together of a set of components to form a nephrocyte diaphragm, a specialized cell-cell junction found between nephrocytes of the insect kidney.


adherens junction assembly

The aggregation, arrangement and bonding together of a set of components to form an adherens junction. An adherens junction is a cell-cell junction composed of the epithelial cadherin-catenin complex at which the cytoplasmic face of the plasma membrane is attached to actin filaments.


S-nitrosoglutathione binding

Binding to S-nitrosoglutathione, a nitrosothiol considered to be a natural nitric oxide (NO) donor involved in S-nitrosylation, and in the storage and transport of nitric oxide in biological systems.


A protein complex that possesses dolichyl-phosphate beta-D-mannosyltransferase activity; contains a catalytic subunit, a regulatory subunit, and a third subunit that stabilizes the complex. In human and several other metazoa, the subunits are named DPM1, DPM2 and DPM3, respectively.


melibiose transmembrane transporter activity

Enables the transfer of melibiose from one side of a membrane to the other. Melibiose is the disaccharide 6-O-alpha-D-galactopyranosyl-D-glucose and occurs as a constituent of the trisaccharide raffinose or in the exudates and nectaries of a number of plants.


Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: melibiose(out) + Na+(out) = melibiose(in) + Na+(in).


melibiose:monoatomic cation symporter activity

Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: melibiose(out) + monovalent cation(out) = melibiose(in) + monovalent cation(in).


negative regulation of cell size

Any process that reduces cell size.


cellular response to neutral pH

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a neutral pH (pH close to 7) stimulus. pH is a measure of the acidity or basicity of an aqueous solution.


positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway

Any process that increases the frequency, rate or extent of metanephric mesenchymal cell migration resulting from the platelet-derived growth factor receptor-beta signaling pathway.


regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway

Any process that modulates the frequency, rate or extent of regulation of metanephric mesenchymal cell migration, by platelet-derived growth factor receptor-beta signaling pathway.


negative regulation of stomach neuroendocrine cell differentiation

Any process that decreases the rate, frequency or extent of the differentiation of a neuroendocrine cell in the stomach.


regulation of stomach neuroendocrine cell differentiation

Any process that modulates the rate, frequency or extent of the differentiation of a neuroendocrine cell in the stomach.


3,4-dihydrocoumarin hydrolase activity

Catalysis of the reaction: 3,4-dihydrocoumarin + H2O = 3-(2-hydroxyphenyl) propionate.


negative regulation of angiotensin-activated signaling pathway

Any process that stops, prevents, or reduces the frequency, rate or extent of the angiotensin-activated signaling pathway.


RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity

Catalysis of the reaction: RNA polymerase II large subunit CTD heptapeptide repeat--phospho-L-threonine (consensus YSPTSPS)(position 4) + H2O = RNA polymerase II large subunit + phosphate.


glycerol-3-phosphatase activity

Catalysis of the reaction: glycerol 3-phosphate + H2O = glycerol + phosphate.


inositol tetrakisphosphate phosphatase activity

Catalysis of the reaction: myo-inositol tetrakisphosphate + H2O = myo-inositol trisphosphate + phosphate.


Catalysis of the reaction: D-fructose 2,6-bisphosphate + H2O = D-fructose-6-phosphate + phosphate.


protein tyrosine phosphatase activity, metal-dependent

Catalysis of the reaction: protein tyrosine phosphate + H2O = protein tyrosine + phosphate. This reaction requires metal ions.


Catalysis of the reaction: 1D-myo-inositol 1,2,4,5,6-pentakisphosphate + H2O = 1D-myo-inositol 1,2,4,6-tetrakisphosphate + phosphate.


Catalysis of the reaction: 8-phospho-3-deoxy-D-manno-oct-2-ulosonate + H2O = 3-deoxy-D-manno-octulosonate + phosphate.


thymidylate 5'-phosphatase activity

Catalysis of the reaction: thymidylate + H2O = thymidine + phosphate.


3-phosphoglycerate phosphatase activity

Catalysis of the reaction: 3-phospho-D-glycerate + H2O = D-glycerate + phosphate.


[3-methyl-2-oxobutanoate dehydrogenase (lipoamide)]-phosphatase activity

Catalysis of the reaction: H2O + [3-methyl-2-oxobutanoate dehydrogenase (lipoamide)] phosphate = phosphate + [3-methyl-2-oxobutanoate dehydrogenase (lipoamide)].


Catalysis of the reaction: nucleoside 2',3'-cyclic phosphate + H2O = nucleoside 3'-phosphate.


inositol monophosphate 4-phosphatase activity

Catalysis of the reaction: myo-inositol 4-phosphate + H2O = myo-inositol + phosphate.


Catalysis of the reaction: [acetyl-CoA carboxylase]-phosphate + H2O = [acetyl-CoA carboxylase] + phosphate.


calcium-dependent phospholipase C activity

Catalysis of the reaction: a phosphatidylcholine + H2O = 1,2-diacylglycerol + choline phosphate. This reaction requires Ca2+.


non-membrane spanning protein tyrosine phosphatase activity

Catalysis of the reaction: non-membrane spanning protein tyrosine phosphate + H2O = non-membrane spanning protein tyrosine + phosphate.


ecdysone-phosphate phosphatase activity

Catalysis of the reaction: ecdysone 22-phosphate + H2O <=> ecdysone + hydrogenphosphate.


lysophosphatidic acid phosphatase activity

Catalysis of the reaction: lysophosphatidic acid + H2O = phosphate + monoacylglycerol.


Catalysis of the reaction: 2-carboxy-D-arabinitol 1-phosphate + H2O = 2-carboxy-D-arabinitol + phosphate.


Catalysis of the reaction: H2O + sphingomyelin = ceramide + choline phosphate + H+.


N-acylphosphatidylethanolamine-specific phospholipase D activity

Catalysis of the release of N-acylethanolamine from N-acyl-phosphatidylethanolamine (NAPE) to generate N-acylethanolamine (NAE).


calmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity

Catalysis of the reactions: nucleoside 3',5'-cyclic GMP + H2O = GMP + H+; this activity is activated by binding to calcium-bound calmodulin.


Catalysis of the reaction: dihydrosphingosine 1-phosphate + H2O = dihydrosphingosine + phosphate.


Catalysis of the reaction: phosphatidylinositol-3,4,5-trisphosphate + H2O = phosphatidylinositol-4,5-bisphosphate + phosphate.


pyridoxal phosphatase activity

Catalysis of the reaction: pyridoxal 5'-phosphate + H2O = pyridoxal + phosphate.


Catalysis of the reaction: beta-D-fructose 2,6-bisphosphate + H2O = beta-D-fructofuranose 2-phosphate + phosphate.


Catalysis of the reaction: 1D-myo-inositol 1,4-bisphosphate + H2O = 1D-myo-inositol 4-phosphate + phosphate.


phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands

Catalysis of the hydrolytic removal of phosphoglycolate from the 3'-terminus of a 3'-phosphoglycolate-terminated DNA strand.


sphingomyelin phosphodiesterase D activity

Catalysis of the reaction: H2O + sphingomyelin = ceramide 1-phosphate + choline + H+.


acid phosphatase activity

Catalysis of the reaction: an orthophosphoric monoester + H2O = an alcohol + phosphate, with an acid pH optimum.


transmembrane receptor protein tyrosine phosphatase activity

Combining with a signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: protein tyrosine phosphate + H2O = protein tyrosine + phosphate.


Catalysis of the reaction: D-galactose-1-phosphate + H2O = D-galactose + phosphate.


diisopropyl-fluorophosphatase activity

Catalysis of the reaction: diisopropyl fluorophosphate + H2O = diisopropyl phosphate + 2 H+ + hydrogen fluoride.


protein tyrosine/serine/threonine phosphatase activity

Catalysis of the reactions: protein serine + H2O = protein serine + phosphate; protein threonine phosphate + H2O = protein threonine + phosphate; and protein tyrosine phosphate + H2O = protein tyrosine + phosphate.


Catalysis of the reaction: phosphatidyl-1D-myo-inositol 1,4,5-trisphosphate + H2O = 1-phosphatidyl-1D-myo-inositol 1,4-bisphosphate + phosphate.


[pyruvate dehydrogenase (lipoamide)] phosphatase activity

Catalysis of the reaction: [pyruvate dehydrogenase (lipoamide)] phosphate + H2O = [pyruvate dehydrogenase (lipoamide)] + phosphate.


Catalysis of the reaction: ceramide-1-phosphate + H2O = ceramide+ phosphate.


trehalose-phosphatase activity

Catalysis of the reaction: trehalose 6-phosphate + H2O = trehalose + phosphate.


Catalysis of the reaction: (2R)-O-phospho-3-sulfolactate + H2O = (R)-3-sulfolactate + phosphate.


pseudouridine 5'-phosphatase activity

Catalysis of the reaction: pseudouridine 5'-phosphate + H2O = pseudouridine + phosphate.


Catalysis of the reaction: 5-amino-6-(5-phosphoribitylamino)-2,4(1H,3H)-pyrimidinedione + H2O = 5-amino-6-ribitylamino-2,4(1H,3H)-pyrimidinedione + orthophosphate.


acid sphingomyelin phosphodiesterase activity

Catalysis of the reaction: H2O + sphingomyelin = ceramide + choline phosphate + H+ in an acidic environment.


Catalysis of the reaction: 1D-myo-inositol 1,3,4,5-tetrakisphosphate + H2O = 1D-myo-inositol 1,3,4-trisphosphate + phosphate.


carbohydrate phosphatase activity

Catalysis of the reaction: carbohydrate phosphate + H2O = carbohydrate + phosphate.


Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O = 1-phosphatidyl-1D-myo-inositol 3-phosphate + phosphate.


streptomycin-6-phosphatase activity

Catalysis of the reaction: H2O + streptomycin 6-phosphate = phosphate + streptomycin.


Catalysis of the reaction: H2O + a 1-phosphatidyl-1D-myo-inositol 5-phosphate = an 1-phosphatidyl-1D-myo-inositol + phosphate.


inositol monophosphate phosphatase activity

Catalysis of the reaction: myo-inositol phosphate + H2O = myo-inositol + phosphate.


protein histidine phosphatase activity

Catalysis of the reaction: protein histidine phosphate + H2O = protein histidine + phosphate.


glucosylglycerol 3-phosphatase activity

Catalysis of the reaction: 2-O-(beta-D-glucosyl)-sn-glycerol 3-phosphate + H2O = 2-O-(beta-D-glucosyl)-sn-glycerol + phosphate.


RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity

Catalysis of the reaction: RNA polymerase II large subunit CTD heptapeptide repeat--phospho-L-tyrosine (consensus YSPTSPS)(position 1) + H2O = RNA polymerase II large subunit + phosphate.


IMP 5'-nucleotidase activity

Catalysis of the reaction: 5'-IMP + H2O = inosine + phosphate.


D,D-heptose 1,7-bisphosphate phosphatase activity

Catalysis of the reaction: D-beta-D-heptose 1,7-bisphosphate + H2O = D-beta-D-heptose 1-phosphate + phosphate.


Catalysis of the reaction: H2O + phosphoenolpyruvate = phosphate + pyruvate.


[phosphorylase] phosphatase activity

Catalysis of the reaction: [phosphorylase a] + 4 H2O = 2 [phosphorylase b] + 4 phosphate.


Catalysis of the reaction: N-acylneuraminate 9-phosphate + H2O = N-acylneuraminate + phosphate.


dGTPase activity

Catalysis of the reaction: dGTP + H2O = 2'-deoxyguanosine + 2 H+ + triphosphate.


phosphoglycolate phosphatase activity

Catalysis of the reaction: 2-phosphoglycolate + H2O = glycolate + phosphate.


transmembrane receptor protein phosphatase activity

Combining with a signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: a phosphoprotein + H2O = a protein + phosphate.


3'-nucleotidase activity

Catalysis of the reaction: a 3'-ribonucleotide + H2O = a ribonucleoside + phosphate.


Catalysis of the hydrolysis of 5'-phosphotyrosyl groups formed as covalent intermediates (in DNA backbone breakage) between DNA topoisomerase II and DNA.


5-phytase activity

Catalysis of the reaction: H2O + myo-inositol hexakisphosphate = phosphate + 1L-myo-inositol 1,2,3,4,6-pentakisphosphate.


glycerol-2-phosphatase activity

Catalysis of the reaction: glycerol 2-phosphate + H2O = glycerol + phosphate.


histidinol-phosphatase activity

Catalysis of the reaction: L-histidinol phosphate + H2O = L-histidinol + phosphate.


Catalysis of the reaction: sphingosine 1-phosphate + H2O = sphingosine + phosphate.


phosphatidate phosphatase activity

Catalysis of the reaction: a 1,2-diacylglycerol 3-phosphate + H2O = a 1,2-diacyl-sn-glycerol + phosphate.


Catalysis of the reaction: inositol-1,3,4,6-tetrakisphosphate + H2O = inositol-1,3,4-trisphosphate + phosphate.


glucose-1-phosphatase activity

Catalysis of the reaction: alpha-D-glucose 1-phosphate + H2O = D-glucose + phosphate.


Catalysis of the reaction: 1D-myo-inositol 2,4,5,6-tetrakisphosphate + H2O = 1D-myo-inositol 2,4,6-trisphosphate + phosphate.


phosphatidylinositol phosphate 5-phosphatase activity

Catalysis of the removal of the 5-phosphate group of a phosphatidylinositol phosphate.


prenylated protein tyrosine phosphatase activity

Catalysis of the reaction: prenylated-protein tyrosine phosphate + H2O = prenylated-protein tyrosine + phosphate.


RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity

Catalysis of the reaction: RNA polymerase II large subunit CTD heptapeptide repeat--phospho-L-serine (consensus YSPTSPS)(position 2) + H2O = RNA polymerase II large subunit + phosphate.


Catalysis of the reaction: H2O + serine phosphoethanolamine = H+ + phosphoethanolamine + serine.


caldesmon-phosphatase activity

Catalysis of the reaction: caldesmon phosphate + H2O = caldesmon + phosphate.


phosphocholine phosphatase activity

Catalysis of the reaction: choline phosphate + H2O = choline + phosphate.


phosphatidylinositol monophosphate phosphatase activity

Catalysis of the reaction: phosphatidyl-1D-myo-inositol monophosphate + H2O = phosphatidylinositol + phosphate.


sorbitol-6-phosphatase activity

Catalysis of the reaction: D-glucitol 6-phosphate + H2O = D-glucitol + phosphate.


Catalysis of the reaction: inositol-1,3,4,5,6-pentakisphosphate + H2O = inositol-1,4,5,6-tetrakisphosphate + phosphate.


tyrosyl-RNA phosphodiesterase activity

Catalysis of the hydrolysis of a 5' tyrosyl-RNA phosphodiester bond between a protein and RNA. In picornaviruses, this covalent bond connects VPg, a viral-encoded protein essential for RNA replication, to the 5' end of all nascent picornavirus genomes; it is cleaved from viral RNA prior to its engaging in protein synthesis.


ribitol-5-phosphatase activity

Catalysis of the reaction: ribitol-5-phosphate + H20 = ribitol + phosphate.


phosphodiesterase I activity

Catalysis of the sequential hydrolytic removal of 5'-nucleotides from the 3'-hydroxy termini of 3'-hydroxy-terminated oligonucleotides.


photoreceptor cyclic-nucleotide phosphodiesterase activity

Catalysis of the reaction: nucleoside cyclic phosphate + H2O = nucleoside phosphate. This reaction is the hydrolysis of bonds in a cyclic nucleotide.


Catalysis of the reaction: galactose-1-phosphate + H2O = galactose + phosphate.


RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity

Catalysis of the reaction: RNA polymerase II large subunit CTD heptapeptide repeat--phospho-L-serine (consensus YSPTSPS)(position 5) + H2O = RNA polymerase II large subunit + phosphate.


Catalysis of the reaction: adenosine 3',5'-bisphosphate + H2O = adenosine 5'-phosphate + phosphate.


Catalysis of the reaction: sn-glycero-3-phosphocholine + H2O = choline phosphate + glycerol + H+.


alkylacetylglycerophosphatase activity

Catalysis of the reaction: 1-alkyl-2-acetyl-sn-glycerol 3-phosphate + H2O = 2-acetyl-1-alkyl-sn-glycerol + phosphate.


phosphoglycerate phosphatase activity

Catalysis of the reaction: 2-phospho-D-glycerate + H2O = D-glycerate + phosphate.


Catalysis of the reaction: guanosine 3',5'-bis(diphosphate) + H2O = guanosine 5'-diphosphate + diphosphate.


dolichyl-phosphatase activity

Catalysis of the reaction: dolichyl phosphate + H2O = dolichol + phosphate.


Catalysis of the reaction: (9S,10S)-10-hydroxy-9-(phosphonooxy)octadecanoate + H2O = (9S,10S)-9,10-dihydroxyoctadecanoate + phosphate.


Catalysis of the reaction: 1D-myo-inositol 1,2,4,5-tetrakisphosphate + H2O = 1D-myo-inositol 1,2,4-trisphosphate + phosphate.


Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 3-phosphate + H2O = 1-phosphatidyl-1D-myo-inositol + phosphate.


polynucleotide 5'-phosphatase activity

Catalysis of the reaction: 5'-phosphopolynucleotide + H2O = polynucleotide + phosphate.


aryldialkylphosphatase activity

Catalysis of the reaction: aryl dialkyl phosphate + H2O = dialkyl phosphate + an aryl alcohol.


Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O = 1-phosphatidyl-1D-myo-inositol 4-phosphate + phosphate.


mannosyl-inositol phosphorylceramide phospholipase activity

Catalysis of the reaction: mannosyl-inositol phosphorylceramide + H2O = C26-phytoceramide + mannosylphosphorylinositol.


phosphatidylglycerophosphatase activity

Catalysis of the reaction: phosphatidylglycerophosphate + H2O = phosphatidylglycerol + phosphate.


triphosphoric monoester hydrolase activity

Catalysis of the hydrolysis of a triphosphoester to give a triphosphate group and a free hydroxyl group.


Catalysis of the reaction: phosphatidyl-1D-myo-inositol-4-phosphate + H2O = phosphatidyl-1D-myo-inositol + phosphate.


protein tyrosine/threonine phosphatase activity

Catalysis of the reactions: protein threonine phosphate + H2O = protein threonine + phosphate; and protein tyrosine phosphate + H2O = protein tyrosine + phosphate.


deoxynucleotide 3'-phosphatase activity

Catalysis of the reaction: a deoxynucleoside 3'-phosphate + H2O = a deoxynucleoside + phosphate.


protein arginine phosphatase activity

Catalysis of the reaction: protein arginine phosphate + H2O = protein arginine + phosphate.


cardiolipin hydrolase activity

Catalysis of the hydrolysis of cardiolipin (1,3-bis(3-phosphatidyl)glycerol), releasing phosphatidic acid (PA).


deoxynucleoside triphosphate hydrolase activity

Catalysis of the reaction: dNTP + H2O = 2'-deoxynucleoside + H+ + triphosphate.


Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate + H2O = 1-phosphatidyl-1D-myo-inositol 5-phosphate + phosphate + 2 H+.


acireductone synthase activity

Catalysis of the reactions: 5-(methylthio)-2,3-dioxopentyl phosphate + H2O = 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + phosphate; (1a) 5-(methylthio)-2,3-dioxopentyl phosphate = 2-hydroxy-5-(methylthio)-3-oxopent-1-enyl phosphate; (1b) 2-hydroxy-5-(methylthio)-3-oxopent-1-enyl phosphate + H2O = 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + phosphate.


NADPH phosphatase activity

Catalysis of the reaction: NADPH + H2O = NADH + hydrogenphosphate.


fructose 1,6-bisphosphate 1-phosphatase activity

Catalysis of the reaction: D-fructose 1,6-bisphosphate + H2O = D-fructose 6-phosphate + phosphate.


5-phospho-alpha-D-ribosyl 1,2-cyclic phosphate phosphodiesterase activity

Catalysis of the reaction: 5-phosphonato-alpha-D-ribose cyclic-1,2-phosphate + H2O <=> H+ + alpha-D-ribose 1,5-bisphosphate.


mannosyl-diinositol phosphorylceramide phospholipase activity

Catalysis of the reaction: mannosyl-diinositol phosphorylceramide + H2O = C26-phytoceramide + mannosyldiphosphorylinositol.


inositol monophosphate 3-phosphatase activity

Catalysis of the reaction: myo-inositol 3-phosphate + H2O = myo-inositol + phosphate.


sedoheptulose-bisphosphatase activity

Catalysis of the reaction: sedoheptulose 1,7-bisphosphate + H2O = sedoheptulose 7-phosphate + phosphate.


Catalysis of the reaction: nucleoside 2',3'-cyclic phosphate + H2O = nucleoside 2'-phosphate.


phosphatidylinositol bisphosphate phosphatase activity

Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol bisphosphate + H2O = phosphatidylinositol phosphate + phosphate.


inositol pentakisphosphate phosphatase activity

Catalysis of the reaction: myo-inositol pentakisphosphate + H2O = myo-inositol tetrakisphosphate + phosphate.


tyrosyl-DNA phosphodiesterase activity

Catalysis of the hydrolysis of phosphotyrosyl groups formed as covalent intermediates (in DNA backbone breakage) between a DNA topoisomerase and DNA.


Catalysis of the reaction: 2-(alpha-D-mannosyl)-3-phosphoglycerate + H2O = 2-(alpha-D-mannosyl)-D-glycerate + phosphate.


Catalysis of the reaction: 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate + H2O = 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + phosphate. 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate is also known as HK-MTPenyl-P, and 1,2-dihydroxy-3-keto-5-methylthiopentene as DHK-MTPene.


myosin-light-chain-phosphatase activity

Catalysis of the reaction: myosin light-chain phosphate + H2O = myosin light chain + phosphate.


cGMP-inhibited cyclic-nucleotide phosphodiesterase activity

Catalysis of the reaction: nucleoside 3',5'-cyclic phosphate + H2O = nucleoside 5'-phosphate; catalytic activity is decreased in the presence of cGMP.


FMN phosphatase activity

Catalysis of the reaction: FMN + H2O = riboflavin + hydrogenphosphate.


calcium-dependent protein serine/threonine phosphatase activity

Catalysis of the reactions: protein serine phosphate + H2O = protein serine + phosphate; and protein threonine phosphate + H2O = protein threonine + phosphate. These reactions require the presence of calcium ions.


NADP phosphatase activity

Catalysis of the reaction: H2O + NADP+ = NAD+ + phosphate.


polynucleotide 3'-phosphatase activity

Catalysis of the reaction: 3'-phosphopolynucleotide + H2O = a polynucleotide + phosphate. Hydrolyzes the free 3'-phosphate resulting from single strand breaks in DNA due to oxidative damage.


inositol monophosphate 1-phosphatase activity

Catalysis of the reaction: myo-inositol 1-phosphate + H2O = myo-inositol + phosphate.


Catalysis of the reaction: a glycerophosphodiester + H2O = an alcohol + sn-glycerol 3-phosphate.


myosin phosphatase activity

Catalysis of the reaction: phosphomyosin + H2O = myosin + phosphate.


5'-deoxynucleotidase activity

Catalysis of the reaction:a 2'-deoxyribonucleoside 5'-monophosphate + H20=a 2'-deoxyribonucleoside + phosphate.


2-deoxyglucose-6-phosphatase activity

Catalysis of the reaction: 2-deoxy-D-glucose-6-phosphate + H2O = 2-deoxy-D-glucose + phosphate.


Catalysis of the reaction: (2R)-2,3-bisphosphoglycerate + H2O = (2R)-2-phosphoglycerate + phosphate.


Catalysis of the reaction: 1D-myo-inositol 1,4,5-trisphosphate + H2O = 1D-myo-inositol 1,4-bisphosphate + phosphate.


protein tyrosine phosphatase activity, via thiol-phosphate intermediate

The catalysis of phosphate removal from a phosphotyrosine using cysteine as a nucleophile and proceed by means of a thiol-phosphate intermediate.


Catalysis of the reaction: S-methyl-3-phospho-1-thio-D-glycerate + H2O = S-methyl-1-thio-D-glycerate + phosphate.


glucose-6-phosphatase activity

Catalysis of the reaction: D-glucopyranose 6-phosphate + H2O = D-glucose + phosphate. D-glucopyranose is also known as D-glucose 6-phosphate.


Catalysis of the reaction: inositol-1,3,4,5-tetrakisphosphate + H2O = inositol-1,4,5-trisphosphate + phosphate.


Catalysis of the reactions: D-myo-inositol 1,4,5-trisphosphate + H2O = myo-inositol 1,4-bisphosphate + phosphate, and 1D-myo-inositol 1,3,4,5-tetrakisphosphate + H2O = 1D-myo-inositol 1,3,4-trisphosphate + phosphate.


Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 3,4-bisphosphate + H2O = 1-phosphatidyl-1D-myo-inositol 3-phosphate + phosphate.


phosphatidylinositol trisphosphate phosphatase activity

Catalysis of the reaction: phosphatidylinositol trisphosphate + H2O = phosphatidylinositol bisphosphate + phosphate.


Catalysis of the reaction: inositol-1,4,5,6-tetrakisphosphate + H2O = inositol-1,4,5-trisphosphate + phosphate.


Catalysis of the reaction: O-phosphoethanolamine + H2O = ethanolamine + phosphate.


Catalysis of the reaction: [glycogen-synthase D] + H2O = [glycogen-synthase I] + phosphate.


Catalysis of the reaction: [acyl-carrier protein] + H2O = 4'-phosphopantetheine + apoprotein.


Catalysis of the reaction: H2O + 1-alkyl-sn-glycero-3-phosphoethanolamine = ethanolamine + 1-alkyl-sn-glycerol 3-phosphate.


Catalysis of the reaction: inositol-1,3,4,6-tetrakisphosphate + H2O = inositol-3,4,6-trisphosphate + phosphate.


Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O = 1-phosphatidyl-1D-myo-inositol phosphate + phosphate.


Catalysis of the reaction: 3-ADP-2-phosphoglycerate + H2O = 3-ADP-glycerate + phosphate.


phosphatidylinositol phosphate 4-phosphatase activity

Catalysis of the removal of the 4-phosphate group of a phosphatidylinositol phosphate.


Catalysis of the reaction: H2O + L-1-glycero-3-phosphocholine = glycerol-3-phosphate + choline.


FMN hydrolase activity

Catalysis of the reaction: FMN + H2O = riboflavin + phosphate.


glycerol-1-phosphatase activity

Catalysis of the reaction: glycerol-1-phosphate + H2O = glycerol + phosphate.


phospholipase D activity

Catalysis of the reaction: a phosphatidylcholine + H2O = choline + a phosphatidate.


Catalysis of the reaction: D-myo-inositol 1,3,4-trisphosphate + H2O = myo-inositol 3,4-bisphosphate + phosphate.


Catalysis of the reaction: H2O + 1-(sn-glycero-3-phospho)-1D-myoinositol = 1D-myo-inositol 1-phosphate + glycerol.


[isocitrate dehydrogenase (NADP+)] phosphatase activity

Catalysis of the reaction: [isocitrate dehydrogenase] phosphate + H2O = [isocitrate dehydrogenase] + phosphate.


phosphatidylglycerol phospholipase C activity

Catalysis of the reaction: a phosphatidylglycerol + H2O = 1,2-diacylglycerol + glycerol 3-phosphate.


D-ribose 2,5-bisphosphate 2-phosphohydrolase activity

Catalysis of the reaction: H2O + D-ribofuranose 2,5-bisphosphate <=> hydrogenphosphate + D-ribofuranose 5-phosphate.


4-phytase activity

Catalysis of the reaction: myo-inositol hexakisphosphate + H2O = 1-myo-inositol 1,2,3,4,5-pentakisphosphate + phosphate.


Catalysis of the reaction: 1D-myo-inositol 4,5-bisphosphate + H2O = 1D-myo-inositol 4-phosphate + phosphate.


Catalysis of the reaction: 2-cis,6-trans,10-trans-geranylgeranyl diphosphate + H2O <=> (13E)-labda-7,13-dien-15-ol + diphosphoric acid.


inositol phosphorylceramide phospholipase activity

Catalysis of the reaction: inositol phosphorylceramide + H2O = C26-phytoceramide + phosphorylinositol.


Catalysis of the reaction: 1-(sn-glycero-3-phospho)-1D-myo-inositol + H2O = sn-glycerol 3-phosphate + myo-inositol + H+.


Catalysis of the reaction: inositol-1,3,4,5,6-pentakisphosphate + H2O = inositol-3,4,5,6-tetrakisphosphate + phosphate.


lipid phosphatase activity

Catalysis of the reaction: a phospholipid + H2O = a lipid + phosphate.


diphosphoric monoester hydrolase activity

Catalysis of the hydrolysis of a diphosphoester to give a diphosphate group and a free hydroxyl group.


JUN kinase phosphatase activity

Catalysis of the reaction: JUN kinase serine/threonine/tyrosine phosphate + H2O = JUN kinase serine/threonine/tyrosine + phosphate.


Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 3,4-bisphosphate + H2O = 1-phosphatidyl-1D-myo-inositol phosphate + phosphate.


Catalysis of the reaction: cyclic di-3',5'-guanylate + H2O = 5'-phosphoguanylyl(3'->5')guanosine + H+.


inositol phosphosphingolipid phospholipase activity

Catalysis of the reaction: inositol phosphosphingolipid + H2O = sphingolipid + phosphorylinositol.


Catalysis of the reaction: 1D-myo-inositol 3,4-bisphosphate + H2O = 1D-myo-inositol 3-phosphate + phosphate.


alkaline phosphatase activity

Catalysis of the reaction: an orthophosphoric monoester + H2O = an alcohol + phosphate, with an alkaline pH optimum.


phosphatidylinositol phosphate phosphatase activity

Catalysis of the reaction: phosphatidylinositol phosphate(n) + H2O = phosphatidylinositol phosphate(n-1) + phosphate. This reaction is the removal of a phosphate group from a phosphatidylinositol phosphate.


RNA polymerase II CTD heptapeptide repeat phosphatase activity

Catalysis of the reaction: RNA polymerase II large subunit CTD heptapeptide repeat--phospho-L-serine/threonine (consensus YSPTSPS) + H2O = RNA polymerase II large subunit + phosphate.


inositol bisphosphate phosphatase activity

Catalysis of the reaction: myo-inositol bisphosphate + H2O = myo-inositol phosphate + phosphate.


phosphatidylcholine phospholipase C activity

Catalysis of the reaction: a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = a 1,2-diacyl-sn-glycerol + H+ + phosphocholine.


fructose-1-phosphatase activity

Catalysis of the reaction: beta-D-fructofuranose 1-phosphate + H2O <=> beta-D-fructofuranose + hydrogenphosphate.


sucrose-phosphate phosphatase activity

Catalysis of the reaction: sucrose 6F-phosphate + H2O = sucrose + phosphate.


RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity

Catalysis of the reaction: RNA polymerase II large subunit CTD heptapeptide repeat--phospho-L-serine (consensus YSPTSPS)(position 7) + H2O = RNA polymerase II large subunit + phosphate.


protein adenylylhydrolase activity

Catalysis of the reaction: adenylyl-protein+ H2O = adenylate + protein; mediates the removal of an adenylyl (adenosine 5'-monophosphate; AMP group) from specific residues of target proteins.


inositol trisphosphate phosphatase activity

Catalysis of the reaction: myo-inositol trisphosphate + H2O = myo-inositol bisphosphate + phosphate.


Catalysis of the reaction: H2O + an N-acylphosphatidylethanolamine = H+ + an N-acylethanolamine + a 1,2-diacyl-sn-glycerol 3-phosphate.


NMN phosphatase activity

Catalysis of the reaction: beta-nicotinamide D-ribonucleotide (NMN-) + H2O = beta-nicotinamide D-riboside (nicotinamide ribose, NmR) + phosphate.


phosphoric triester hydrolase activity

Catalysis of the hydrolysis of a phosphoric triester.


mannitol-1-phosphatase activity

Catalysis of the reaction: D-mannitol 1-phosphate + H2O = D-mannitol + 2 H+ + phosphate.


[hydroxymethylglutaryl-CoA reductase (NADPH)]-phosphatase activity

Catalysis of the reaction: H2O + [hydroxymethylglutaryl-CoA reductase (NADPH)] phosphate = phosphate + [hydroxymethylglutaryl-CoA reductase (NADPH)].


sugar-terminal-phosphatase activity

Catalysis of the reaction: H2O + sugar phosphorylated on the terminal carbon = a sugar + phosphate.


prenyl-diphosphatase activity

Catalysis of the reaction: prenyl diphosphate + H2O = prenol + diphosphate.


Catalysis of the reaction: dolichyl beta-D-mannosyl phosphate + H2O = dolichol-phosphate + mannose.


[pyruvate kinase]-phosphatase activity

Catalysis of the reaction: [pyruvate kinase] phosphate + H2O = [pyruvate kinase] + phosphate.


Catalysis of the reaction: phosphatidylinositol-3,5-bisphosphate + H2O = phosphatidylinositol-3-phosphate + orthophosphate.


Catalysis of the hydrolysis of 3'-phosphotyrosyl groups formed as covalent intermediates (in DNA backbone breakage) between DNA topoisomerase I and DNA.


thiamine phosphate phosphatase activity

Catalysis of the reaction: thiamine phosphate + H2O = thiamine + phosphate.


Catalysis of the reaction: H2O + 6-(D-glucose-1-phospho)-D-mannosylglycoprotein = D-mannosylglycoprotein + D-glucose-alpha-1-phosphate.


Catalysis of the reaction: glycerol 1,2-cyclic phosphate + H2O = glycerol 1-phosphate + H+.


Catalysis of the reaction: H2O + CMP-N-acylneuraminate = N-acylneuraminate + CMP.


neutral sphingomyelin phosphodiesterase activity

Catalysis of the reaction: H2O + sphingomyelin = ceramide + choline phosphate + H+ in a neutral environment.


Catalysis of the reaction: H2O + an ecdysteroid 22-phosphate = hydrogenphosphate + an ecdysteroid.


Catalysis of the reaction: L-galactose-1-phosphate + H2O = L-galactose + phosphate.


inositol hexakisphosphate 2-phosphatase activity

Catalysis of the reaction: myo-inositol hexakisphosphate + H2O = myo-inositol 1,3,4,5,6-pentakisphosphate + phosphate.


calmodulin-dependent protein phosphatase activity

Catalysis of the reaction: protein serine/threonine phosphate + H2O = protein serine/threonine + phosphate, dependent on the presence of calcium-bound calmodulin.


3',5'-nucleotide bisphosphate phosphatase activity

Catalysis of the reaction: 3',5'-nucleoside bisphosphate + H20 = 5'-nucleoside monophosphate + phosphate.


GPI-mannose ethanolamine phosphate phosphodiesterase activity

A phosphoric diester hydrolase activity that removes the ethanolamine phosphate from mannose 2 of a GPI anchor.


5-phospho-alpha-D-ribose 1,2-cyclic phosphate 1-phosphohydrolase activity

Catalysis of the reaction: 5-phosphonato-alpha-D-ribose cyclic-1,2-phosphate + H2O <=> D-ribofuranose 2,5-bisphosphate + H+.


7,8-dihydro-D-neopterin 2',3'-cyclic phosphate phosphodiesterase activity

Catalysis of the reaction: 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate + H2O = 7,8-dihydroneopterin 3'-phosphate + H+.


Catalysis of the reaction: D-myo-inositol 1,3,4-trisphosphate + H2O = myo-inositol 1,3-bisphosphate + phosphate.


L-phosphoserine phosphatase activity

Catalysis of the reaction: O-phospho-L-serine + H2O = L-serine + phosphate, on a free amino acid.


XMP 5'-nucleosidase activity

Catalysis of the reaction: 5'XMP + H20 = phosphate + xanthosine.


Catalysis of the reaction: 1D-myo-inositol 4,5,6-trisphosphate + H2O = 1D-myo-inositol 4,6-bisphosphate + phosphate.


monoterpenyl-diphosphatase activity

Catalysis of the reaction: monoterpenyl diphosphate + H2O = monoterpenol + diphosphate.


phosphatidylinositol phospholipase C activity

Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O = 1,2-diacylglycerol + 1D-myo-inositol 1,4,5-trisphosphate + H+.


calmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity

Catalysis of the reactions: 3',5'-cyclic AMP + H2O = AMP + H+ and 3',5'-cyclic GMP + H2O = GMP + H+; this activity is activated by binding to calcium-bound calmodulin.


1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O = 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + phosphate.


cGMP-stimulated cyclic-nucleotide phosphodiesterase activity

Catalysis of the reaction: nucleoside 3',5'-cyclic phosphate + H2O = nucleoside 5'-phosphate; catalytic activity is increased in the presence of cGMP.


glycosylphosphatidylinositol phospholipase D activity

Catalysis of the reaction: glycoprotein phosphatidylinositol + H2O = phosphatidate + glycoprotein inositol.


L-threonine O-3-phosphate phosphatase activity

Catalysis of the reaction: O-phospho-L-threonine + H2O = L-threonine + hydrogenphosphate.