methylseleninic acid reductase activity

Catalysis of the reaction: NADPH + H+ + CH3SeO2H => NADP+ + CH3SeOH + H2O.


regulation of olefin metabolic process

biolink:BiologicalProcess biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:Occurrent biolink:OntologyClass biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

Any process that modulates the frequency, rate or extent of olefin metabolic process.


allantoin biosynthetic process

The chemical reactions and pathways resulting in the formation of allantoin, (2,5-dioxo-4-imidazolidinyl)urea.


serotonin-gated monoatomic cation-selective channel activity

biolink:MolecularActivity biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:Occurrent biolink:OntologyClass biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

Enables the transmembrane transfer of a cation by a channel that opens when serotonin has been bound by the channel complex or one of its constituent parts.


Catalysis of the reaction: 3-isopropylbut-3-enoyl-CoA + H2O = 3-isopropylbut-3-enoic acid + CoASH.


eye field cell fate commitment involved in camera-type eye formation

The commitment of neurectodermal cells to cells of the eye field and their capacity to differentiate into eye field cells. Eye field cells are neurectodermal cells that will form the optic placode.


regulation of spore germination

Any process that modulates the frequency, rate or extent of spore germination.


response to external biotic stimulus

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external biotic stimulus, an external stimulus caused by, or produced by living things.


(E)-beta-ocimene synthase activity

Catalysis of the reaction: geranyl diphosphate = (E)-beta-ocimene + diphosphate.


lavandulyl diphosphate synthase activity

Catalysis of the reaction: 2 dimethylallyl diphosphate = diphosphate + lavandulyl diphosphate.


Catalysis of the reactions: cholest-5-ene-3beta,25-diol + NADPH + H+ + O2 = cholest-5-ene-3beta,7alpha,25-triol + NADP+ + H2O, and cholest-5-ene-3beta,27-diol + NADPH + H+ + O2 = cholest-5-ene-3beta,7alpha,27-triol + NADP+ + H2O.


gibberellin metabolic process

The chemical reactions and pathways involving gibberellin. Gibberellins are a class of highly modified terpenes that function as plant growth regulators.


Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + glycochenodeoxycholate = adenosine 3',5'-diphosphate + glycochenodeoxycholate 7-sulfate + H+.


regulation of Ral protein signal transduction

Any process that modulates the frequency, rate or extent of Ral protein signal transduction.


epithelial cell apoptotic process involved in palatal shelf morphogenesis

An apoptotic process in a palatal shelf epithelial cell that contributes to the shaping of the palatal shelf.


glycolytic fermentation to propionate

Glycolytic fermentation resulting in the catabolism of glucose to propionate, yielding energy in the form of ATP; an alternative to the acrylate pathway to produce propionate.


negative regulation of cellular response to alkaline pH

Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to alkalinity.


pyrene dioxygenase activity

Catalysis of the reaction: pyrene + 2 H+ + 2 e- + O2 = cis-4,5-dihydroxy-4,5-dihydropyrene.


muscle cell apoptotic process

A form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle a muscle cell and result in its death. A muscle cell is a mature contractile cell, commonly known as a myocyte, that forms one of three kinds of muscle.


neutral lipid metabolic process

The chemical reactions and pathways involving neutral lipids, lipids only soluble in solvents of very low polarity.


ganglioside GP1c binding

Binding to ganglioside GP1c.


hypoxanthine oxidase activity

Catalysis of the reaction: hypoxanthine + H2O + O2 = xanthine + H2O2.


mechanoreceptor activity

Combining with a mechanical force and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity or state as part of signal transduction.


negative regulation of microglial cell migration

Any process that stops, prevents or reduces the frequency, rate or extent of microglial cell migration.


fatty acid transmembrane transporter activity

Enables the transfer of fatty acids from one side of a membrane to the other. Fatty acids are aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis.


peptidyl-serine acetylation

The acetylation of peptidyl-serine.


detection of electrical stimulus

The series of events by which an electrical stimulus is received and converted into a molecular signal.


negative regulation of transformation of host cell by virus

Any process that stops, prevents or reduces the frequency, rate or extent of transformation of host cell by virus.


cellular response to cordycepin

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cordycepin stimulus.


anthranilate-CoA ligase activity

Catalysis of the reaction: ATP + anthranilate + CoA = AMP + diphosphate + anthranilyl-CoA.


chlorophyll biosynthetic process

The chemical reactions and pathways resulting in the formation of chlorophyll, any compound of magnesium complexed in a porphyrin (tetrapyrrole) ring and which functions as a photosynthetic pigment, from less complex precursors.


aorta smooth muscle tissue morphogenesis

The process in which the structure of the smooth muscle tissue surrounding the aorta is generated and organized. An aorta is an artery that carries blood from the heart to other parts of the body.


Catalysis of the reaction: 2-oxo-3-enoate-4-benzenoid + H2O = pyruvate + benzaldehyde derivative. Substrates are (3E)-4-(5-amino-2-hydroxy-phenyl)-2-oxo-but-3-ene-1-oic-acid (forms 5-aminosalicylaldehyde) and trans-o-hydroxybenzylidenepyruvate (forms salicylaldehyde).


formate dehydrogenase (quinone) activity

Catalysis of the reaction: formate + a quinone = CO2 + a quinol.


G protein-coupled amine receptor activity

Combining with an extracellular amine and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.


pentraxin receptor activity

Combining with a pentraxin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


heme C metabolic process

The chemical reactions and pathways involving heme c, a derivative of heme found in cytochromes c, b4, and f.


vascular associated smooth muscle cell fate specification

The process in which a cell becomes capable of differentiating autonomously into a vascular smooth muscle cell in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed. A vascular smooth muscle cell is a non-striated, elongated, spindle-shaped cell found lining the blood vessels.


thiazole synthase activity

Catalysis of the reaction: 1-deoxy-D-xylulose 5-phosphate + 2-iminoacetate + thiocarboxy-adenylate-[sulfur-carrier protein ThiS] = 2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate + [sulfur-carrier protein ThiS] + 2 H2O.


tellurite transmembrane transporter activity

Enables the transfer of tellurite from one side of a membrane to the other. Tellurite is a salt of tellurous acid or an oxide of tellurium which occurs sparingly in tufts of white or yellowish crystals.


superior vena cava morphogenesis

The process in which the anatomical structure of superior vena cava generated and organized. The superior vena cava is a blood vessel that transports blood from the upper body to the heart.


E-series resolvin biosynthetic process

The chemical reactions and pathways resulting in the formation of resolvin family E-series, hydroxy fatty acids derived from icosapentaenoic acid.


oxazole or thiazole metabolic process

The chemical reactions and pathways involving oxazole or thiazole, five-membered heterocyclic ring structures containing an oxygen and a sulfur, respectively, in the 1-position and a nitrogen in the 3-position.


5-hydroxymethyluracil DNA N-glycosylase activity

Catalysis of the removal of 5-hydroxymethyluracil bases by cleaving the N-C1' glycosidic bond between the oxidized pyrimidine and the deoxyribose sugar.


halohydrin hydrogen-halide-lyase B activity

Catalysis of the elimination of HCl from a chloropropanol, yielding an epoxypropane.


lipoprotein biosynthetic process

The chemical reactions and pathways resulting in the formation of any conjugated, water-soluble protein in which the covalently attached nonprotein group consists of a lipid or lipids.


cGMP binding

Binding to cGMP, the nucleotide cyclic GMP (guanosine 3',5'-cyclophosphate).


cellular response to epinephrine stimulus

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an epinephrine stimulus. Epinephrine is a catecholamine that has the formula C9H13NO3; it is secreted by the adrenal medulla to act as a hormone, and released by certain neurons to act as a neurotransmitter active in the central nervous system.


negative regulation of cytokinin-activated signaling pathway

Any process that stops, prevents, or reduces the frequency, rate or extent of cytokinin signaling.


rejection of pollen from other species

The recognition and rejection of pollen of one species by cells in the stigma of another species.


vestibular reflex

A reflex process in which a response to an angular or linear acceleration stimulus begins with an afferent nerve impulse from a receptor in the inner ear and ends with the compensatory action of eye muscles. Signaling never reaches a level of consciousness.


protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity

Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + lactose(out) = protein histidine + lactose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.


pulmonary myocardium development

The progression of the pulmonary myocardium over time, from its initial formation to the mature structure. The pulmonary myocardium is the myocardial tissue present in the pulmonary vein.


Catalysis of the reaction: 1-hydroxypyrene + XCH3 = 1-methoxypyrene + HX.


Catalysis of the reaction: NADPH + H+ + sulfur = hydrogen sulfide + NADP+.


protein-containing complex assembly involved in synapse maturation

The aggregation, arrangement and bonding together of a set of components to form a protein complex that contributes to synapse maturation.


capsule polysaccharide biosynthetic process

The chemical reactions and pathways resulting in the formation of polysaccharides that make up the capsule, a protective structure surrounding some species of bacteria and fungi.


energy derivation by oxidation of reduced inorganic compounds

The chemical reactions and pathways by which a cell derives energy from inorganic compounds; results in the oxidation of the compounds from which energy is released.


platelet-derived growth factor alpha-receptor activity

Combining with platelet-derived growth factor isoform PDGF-AA, PDGF-BB or PDGF-AB to initiate a change in cell activity.


regulation of RNA export from nucleus

Any process that modulates the frequency, rate or extent of the directed movement of RNA from the nucleus to the cytoplasm.


Catalysis of the reaction: UDP-galactose + kaempferol = UDP + kaempferol 3-O-beta-D-galactoside.


presynapse assembly

The aggregation, arrangement and bonding together of a set of components to form a presynapse.


regulation of CD8-positive, alpha-beta T cell differentiation

Any process that modulates the frequency, rate, or extent of CD8-positive, alpha-beta T cell differentiation.


axon arborization

The process in which the terminal anatomical structures of an axon are generated and organized into branches of specialised projections, or boutons. An axon is the long process of a neuron that conducts nerve impulses, usually away from the cell body to the terminal branches.


protein alpha-1,2-demannosylation

The removal of one or more alpha 1,2-linked mannose residues from a mannosylated protein.


establishment of viral latency

A process by which a virus establishes a latent state within its host, either as an integrated provirus within the host genome or as an episome, where viral genome remains in the cytoplasm or nucleus as distinct objects.


regulation of synaptic vesicle lumen acidification

Any process that modulates the frequency, rate or extent of synaptic vesicle lumen acidification.


Catalysis of the reaction: anthocyanidin 3,5-di-O-beta-D-glucoside + caffeoyl-CoA = pelargonidin 3-O-(6-O-caffeoyl-beta-D-glucoside) 5-O-beta-D-glucoside + coenzyme A.


Catalysis of the reaction: myo-inositol + UDP-galactose = O-alpha-D-galactosyl-(1,3)-1D-myo-inositol + UDP.


multicellular organismal-level water homeostasis

A chemical homeostatic process involved in the maintenance of a steady state level of water within extracellular body fluids, such as blood, xylem or phloem, of a multicellular organism. This is distinct from maintenance of cellular homeostasis, which occurs within a cell.


regulation of lymphocyte apoptotic process

Any process that modulates the occurrence or rate of lymphocyte death by apoptotic process.


exon-exon junction complex disassembly

The disaggregation of an exon-exon junction complex into its constituent components.


dimethylargininase activity

Catalysis of the reaction: N(G),N(G)-dimethyl-L-arginine + H2O = dimethylamine + L-citrulline.


Catalysis of the reaction: aldose 1-phosphate + NDP = phosphate + NDP-aldose.


ubiquinone biosynthetic process via 3,4-dihydroxy-5-polyprenylbenzoate

The chemical reactions and pathways resulting in the formation of ubiquinone, via the intermediates 3,4-dihydroxy-5-polyprenylbenzoate and 3-methoxy-4-hydroxy-5-polyprenylbenzoate.


response to interleukin-2

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-2 stimulus.


transcription elongation by RNA polymerase I

The extension of an RNA molecule after transcription initiation and promoter clearance at an RNA polymerase I specific promoter by the addition of ribonucleotides catalyzed by RNA polymerase I.


heart jogging

The morphogenetic process in which the heart cone is displaced to the left with respect to the vector of the anterior-posterior axis.


histone H3R8 arginine deiminase activity

Catalysis of the reaction: H2O + histone H3 L-arginyl (position 8)= histone H3 L-citrullyl (position 8) + NH4+, resulting in histone H3 citrullination at position 8.


The process that gives rise to the patterns of cell differentiation that will arise in the chitin-based adult cuticle. An example of this process is adult chitin-based cuticle pattern formation in Drosophila melanogaster.


dibutyl phthalate binding

Binding to dibutyl phthalate, C(16)H(22)O(4).


RNA dinucleotide insertion

The modification of an RNA molecule by insertion of a dinucleotide.


lipopolysaccharide floppase activity

Enables the transfer of a lipopolysaccharide from the cytosolic to the exoplasmic leaftlet of a membrane, using energy from the hydrolysis of ATP.


response to gamma radiation

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gamma radiation stimulus. Gamma radiation is a form of electromagnetic radiation (EMR) or light emission of a specific frequency produced from sub-atomic particle interaction, such as electron-positron annihilation and radioactive decay. Gamma rays are generally characterized as EMR having the highest frequency and energy, and also the shortest wavelength, within the electromagnetic radiation spectrum.


negative regulation of glutamine transport

Any process that stops, prevents or reduces the frequency, rate or extent of glutamine transport.


regulation of plasma cell differentiation

Any process that modulates the frequency, rate or extent of plasma cell differentiation.


hepatocyte apoptotic process

Any apoptotic process in a hepatocyte, the main structural component of the liver.


G protein-coupled UDP receptor activity

Combining with a nucleotide and transmitting the signal to a heterotrimeric G-protein complex to initiate a change in cell activity, activated by UDP.


glycine metabolic process

The chemical reactions and pathways involving glycine, aminoethanoic acid.


neuron fate commitment

The process in which the developmental fate of a cell becomes restricted such that it will develop into a neuron.


compartment pattern specification

The regionalization process in which embryonic segments are divided into compartments that will result in differences in cell differentiation.


racemase activity, acting on amino acids and derivatives

Catalysis of the interconversion of the two enantiomers of a chiral amino acid or amino acid derivative.


positive regulation of heart induction

Any process that activates or increases the frequency, rate or extent of heart induction.


glucuronate transmembrane transporter activity

Enables the transfer of glucuronate from one side of a membrane to the other. Glucuronate is the uronic acid formally derived from glucose by oxidation of the hydroxymethylene group at C-6 to a carboxyl group.


phosphoenolpyruvate carboxykinase (diphosphate) activity

Catalysis of the reaction: diphosphate + oxaloacetate = CO2 + phosphate + phosphoenolpyruvate.


positive regulation of epidermis development

Any process that activates or increases the frequency, rate or extent of epidermis development.


Catalysis of the reaction: UDP-alpha-D-glucose + 7-hydroxyflavone <=> 7-O-beta-D-glucosyl-7-hydroxyflavone + UDP + H+.


sorocarp stalk development

The process whose specific outcome is the progression of the sorocarp stalk over time, from its formation to the mature structure. The sorocarp stalk is a tubular structure that consists of cellulose-covered cells stacked on top of each other and surrounded by an acellular stalk tube composed of cellulose and glycoprotein. An example of this process is found in Dictyostelium discoideum.


Enables the transfer of UDP-beta-L-arabinofuranose from one side of a membrane to the other.


negative regulation of tRNA export from nucleus

Any process that stops, prevents, or reduces the frequency, rate or extent of tRNA export from nucleus.


clathrin coating of Golgi vesicle, trans-Golgi to endosome targeting

The addition of clathrin and adaptor proteins to Golgi membranes during the formation of transport vesicles that will move from the trans-Golgi to the endosome, forming a vesicle coat.


regulation of vacuolar transport

Any process that modulates the frequency, rate or extent of vacuolar transport.


regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway

Any process that modulates the frequency, rate or extent of oxidative stress-induced neuron intrinsic apoptotic signaling pathway.


Catalysis of the reaction: corticosterone + reduced adrenal ferredoxin + O2 = 18-hydroxycorticosterone + oxidized adrenal ferredoxin + H2O.


endoplasmic reticulum-derived vesicle fusion with endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane

The joining of the lipid bilayer membrane around an endoplasmic reticulum-derived vesicle to the lipid bilayer membrane of the ERGIC. Such vesicles include COPII-coated transport vesicles involved in anterograde transport.


costunolide synthase activity

Catalysis of the reaction: germacra-1(10),4,11(13)-trien-12-oate + O2 + NADPH + 2 H+ = costunolide + 2 H2O + NADP.


zeaxanthin 2-beta-hydroxylase activity

Catalysis of the reaction: zeaxanthin + O2 + NADH + H+ <=> caloxanthin + H2O + NAD.


detoxification of inorganic compound

Any process that reduces or removes the toxicity of inorganic compounds. These include transport of such compounds away from sensitive areas and to compartments or complexes whose purpose is sequestration of inorganic compounds.


cellobiose epimerase activity

Catalysis of the reaction: cellobiose = D-glucosyl-D-mannose.


alkan-1-ol dehydrogenase (acceptor) activity

Catalysis of the reaction: primary alcohol + acceptor = aldehyde + reduced acceptor.


regulation of plant organ morphogenesis

Any process that modulates the frequency, rate or extent of plant organ morphogenesis.


plastid membrane organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of either of the lipid bilayers surrounding a plastid.


nucleoside triphosphate adenylate kinase activity

Catalysis of the reaction: nucleoside triphosphate + AMP = nucleoside diphosphate + ADP.


chlorinated hydrocarbon catabolic process

The chemical reactions and pathways resulting in the breakdown of chlorinated hydrocarbons, compounds derived from hydrocarbons by replacing one or more hydrogen atoms with chlorine atoms.


regulation of dendritic spine development

Any process that modulates the rate, frequency, or extent of dendritic spine development, the process whose specific outcome is the progression of the dendritic spine over time, from its formation to the mature structure.


UGU codon-amino acid adaptor activity

A triplet codon-amino acid adaptor activity that recognizes a UGU codon.


Catalysis of the reaction: dibenzothiophene-5,5-dioxide + O2 + 2 NADH + H+ = 2 NAD+ + H2O + 2'-hydroxybiphenyl-2-sulfinate.


p-cumate metabolic process

The chemical reactions and pathways involving p-cumate.


peptide N-acetyltransferase activity

Catalysis of the acetylation of an amino acid residue of a peptide or protein, according to the reaction: acetyl-CoA + peptide = CoA + N-acetylpeptide.


B cell tolerance induction

A process involving any mechanism for tolerance induction in B cells.


FMN reductase (NAD(P)H) activity

Catalysis of the reaction: FMNH2 + NAD(P)+ = FMN + NAD(P)H + H+. This reaction can utilize NADH and NADPH with similar reaction rates.


L-arginine transmembrane transporter activity

Enables the transfer of L-arginine from one side of a membrane to the other.


barbiturase activity

Catalysis of the reaction: barbiturate + H2O = malonate + urea.


negative regulation of eosinophil migration

Any process that stops, prevents or reduces the frequency, rate or extent of eosinophil migration.


DNA-templated transcription elongation

The extension of an RNA molecule after transcription initiation and promoter clearance at a DNA-dependent RNA polymerase promoter by the addition of ribonucleotides catalyzed by an RNA polymerase.


negative regulation of cardiac muscle cell proliferation

Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle cell proliferation.


linoleic acid epoxygenase activity

Catalysis of an NADPH- and oxygen-dependent reaction that converts linoleic acid to a cis-epoxyoctadecenoic acid.


negative regulation of RIG-I signaling pathway

Any process that stops, prevents, or reduces the frequency, rate or extent of the RIG-I signaling pathway.


defense response to insect

A response to protect an organism from a directly detected or perceived external threat from an insect or insects to that organism.


dihydrogeranylgeranyl-chlorophyll a reductase activity

Catalysis of the reaction: H+ + dihydrogeranylgeranyl-chlorophyll a + NADPH = tetrahydrogeranylgeranyl-chlorophyll a + NADP.


Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: alpha-glucoside(out) + H+(out) = alpha-glucoside(in) + H+(in). Alpha-glucosides include trehalose, maltose, turanose, isomaltose, alpha-methylglucoside, maltotriose, palatinose, trehalose and melezitose.


chondroitin hydrolase activity

Catalysis of the hydrolysis of hexosaminic linkages in chondroitin, a linear polymer structure composed of the repeating disaccharide unit [->4)-D-glucuronic acid-(1->3)-N-acetyl-D-galactosamine-(1-], also written as [->4GlcUA1->3GalNAc1-].


lung epithelium development

The biological process whose specific outcome is the progression of the lung epithelium from an initial condition to its mature state. This process begins with the formation of lung epithelium and ends with the mature structure. The lung epithelium is the specialized epithelium that lines the inside of the lung.


3 iron, 4 sulfur cluster binding

Binding to a 3 iron, 4 sulfur (3Fe-4S) cluster; this cluster consists of three iron atoms, with the inorganic sulfur atoms found between the irons and acting as bridging ligands. It is essentially a 4Fe-4S cluster with one iron missing.


adhesion of symbiont germination tube to host

The attachment of a germination tube of the symbiont to its host via adhesion molecules. The host is defined as the larger of the organisms involved in a symbiotic interaction.


negative regulation of myotube cell migration

Any process that stops, prevents, or reduces the frequency, rate or extent of myotube cell migration.


positive regulation of response to toluene

Any process that activates or increases the frequency, rate or extent of response to toluene.


somatic motor neuron fate commitment

The commitment of unspecified motor neurons to specific motor neuron cell along the anterior-posterior axis of the spinal cord and their capacity to differentiate into specific motor neurons.


citramalate lyase activity

Catalysis of the reaction: S-citramalate = acetate + pyruvate.


glucose-6-phosphate dehydrogenase (coenzyme F420) activity

Catalysis of the reaction: beta-D-glucose 6-phosphate + coenzyme F420 + H+ = 6-O-phosphono-D-glucono-1,5-lactone + reduced coenzyme F420.


UCC codon-amino acid adaptor activity

A triplet codon-amino acid adaptor activity that recognizes a UCC codon.


embryonic plasmatocyte differentiation

The process in which an embryonic mesoderm-derived hemocyte precursor cell acquires the specialized features of the phagocytic blood-cell type, the plasmatocyte.


establishment of planar polarity involved in metanephric nephron morphogenesis

Coordinated organization of groups of cells in the plane of an epithelium that contributes to the shaping of a nephron in the metanephros.


cholesterol transfer activity

Removes cholesterol from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle.


arogenate dehydrogenase [NAD(P)+] activity

Catalysis of the reaction: L-arogenate + NAD(P)+ = L-tyrosine + NAD(P)H + CO2.


histone H2AS1 kinase activity

Catalysis of the reaction: histone H2A-serine (position 1) + ATP = histone H2A-phosphoserine (position 1) + ADP. This reaction is the addition of a phosphate group to the serine residue at position 1 of histone H2A.


regulation of early stripe melanocyte differentiation

Any process that modulates the frequency, rate or extent of early stripe melanocyte differentiation.


sequestering of metal ion

The process of binding or confining metal ions such that they are separated from other components of a biological system.


NADH binding

Binding to the reduced form, NADH, of nicotinamide adenine dinucleotide, a coenzyme involved in many redox and biosynthetic reactions.


relaxation of smooth muscle

A process in which the extent of smooth muscle contraction is reduced. Smooth muscle differs from striated muscle in the much higher actin/myosin ratio, the absence of conspicuous sarcomeres and the ability to contract to a much smaller fraction of its resting length.


parathion metabolic process

The chemical reactions and pathways involving parathion, a highly toxic organophosphate compound formerly used as a broad spectrum insecticide, acaricide, fumigant and nematocide. Degradation of parathion by sunlight or liver enzymes can result in the formation of the active compound paraoxon which interferes with the nervous system through cholinesterase inhibition.


labyrinthine layer development

The process in which the labyrinthine layer of the placenta progresses, from its formation to its mature state.


generation of catalytic spliceosome for first transesterification step

Formation of a catalytic spliceosome complex ready to perform the first splicing reaction. This occurs by an ATP-dependent conformational change of the pre-catalytic spliceosome.


fructan metabolic process

The chemical reactions and pathways involving fructan, a polysaccharide consisting of fructose residues.


dADP binding

Binding to dADP, deoxyadenosine diphosphate.


glucocorticoid mediated signaling pathway

biolink:Pathway biolink:BiologicalProcess biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:OntologyClass biolink:Occurrent biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

The series of molecular signals mediated by the detection of a glucocorticoid hormone.


1,2-dehydroreticulinium reductase (NADPH) activity

Catalysis of the reaction: (R)-reticuline + NADP+ = 1,2-dehydroreticuline + H+ + NADPH.


nuclear dicing body assembly

The aggregation, arrangement and bonding together of a set of components to form a nuclear dicing body.


Catalysis of the reaction: 2-hydroxy-4-isopropenylcyclohexane-1-carboxyl-CoA = 4-isopropenyl-2-ketocyclohexane-1-carboxyl-CoA + 2 H+ + 2 e-.


Catalysis of the reaction: malonyl-CoA + H+ + a long-chain acyl-[acp] + a reduced electron acceptor = 2 carbon dioxide + coenzyme A + a terminal olefin + a holo-[acyl-carrier protein] + an oxidized electron acceptor.


negative regulation of response to reactive oxygen species

Any process that stops, prevents or reduces the frequency, rate or extent of response to reactive oxygen species.


choline metabolic process

The chemical reactions and pathways involving choline (2-hydroxyethyltrimethylammonium), an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids and in the neurotransmitter acetylcholine.


regulation of thyroid hormone mediated signaling pathway

Any process that modulates the frequency, rate or extent of a thyroid hormone mediated signaling pathway.


corpus callosum morphogenesis

The process in which the anatomical structures of the corpus callosum are generated and organized. The corpus callosum is a thick bundle of nerve fibers comprising a commissural plate connecting the two cerebral hemispheres. It consists of contralateral axon projections that provides communications between the right and left cerebral hemispheres.


intraciliary transport particle B binding

Binding to an intraciliary transport particle B (IFT B) complex.


amylopectin metabolic process

The chemical reactions and pathways involving an amylopectin.


borate binding

Binding to borate, the anion (BO3)3-.


cerebroside-sulfatase activity

Catalysis of the reaction: a cerebroside 3-sulfate + H2O = a cerebroside + sulfate.


glutamate catabolic process to ornithine

The chemical reactions and pathways resulting in the breakdown of glutamate into other compounds, including ornithine.


protein import into peroxisome matrix, docking

The process in which a complex formed of a peroxisome targeting sequence (PTS) receptor bound to a PTS-bearing protein docks with translocation machinery in the peroxisomal membrane.


regulation of cell cycle switching, mitotic to meiotic cell cycle

Any process that modulates the frequency, rate, or extent of mitotic to meiotic cell cycle switching, the process in which a cell switches cell cycle mode from mitotic to meiotic division.


mitotic G1 phase

The cell cycle 'gap' phase which is the interval between the completion of DNA segregation by mitosis and the beginning of DNA synthesis.


TCR signalosome assembly

The aggregation, arrangement and bonding together of a set of components to form a TCR signalosome.


regulation of ergot alkaloid biosynthetic process

Any process that modulates the frequency, rate or extent of ergot alkaloid biosynthetic process.


lactam biosynthetic process

The chemical reactions and pathways resulting in the formation of lactams, any cyclic amides of amino carboxylic acids, having a 1-azacycloalkan-2-one structure, or analogues having unsaturation or heteroatoms replacing one or more carbon atoms of the ring.


T-helper 17 cell lineage commitment

The process in which a CD4-positive, alpha-beta T cell becomes committed to becoming a T-helper 17 cell, a CD4-positive, alpha-beta T cell with the phenotype RORgamma-t-positive that produces IL-17.


ABC-type monosaccharide transporter activity

Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + monosaccharide(out) = ADP + phosphate + monosaccharide(in). Ribose, xylose, arabinose, galactose and methylgalactoside are imported.


insulin receptor activity

Combining with insulin receptor ligand and transmitting the signal across the plasma membrane to initiate a change in cell activity.


regulation of forward locomotion

Any process that modulates the speed, mechanical force, or rhythm of the anterior movement of an organism.


endoplasmic reticulum-Golgi intermediate compartment organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endoplasmic reticulum (ER)-Golgi intermediate compartment.


protein-N(PI)-phosphohistidine-mannitol phosphotransferase system transmembrane transporter activity

Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + mannitol(out) = protein histidine + mannitol phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.


kinetochore adaptor activity

The binding activity of a protein that brings the kinetochore and another molecule into contact, permitting those molecules to function in a coordinated way.


rhamnolipid biosynthesis

The chemical reactions and pathways resulting in the formation/production of a glycolipid surfactant that acts as a bacterial biofilm dispersal.


negative regulation of border follicle cell delamination

Any process that decreases the frequency, rate or extent of border cell delamination.


pyrimidine nucleobase metabolic process

The chemical reactions and pathways involving pyrimidine nucleobases, 1,3-diazine, organic nitrogenous bases.


phosphoglycerate kinase (GTP) activity

Catalysis of the reaction: 3-phospho-D-glycerate + GTP = 3-phospho-D-glyceroyl phosphate + GDP + H+.


inositol hexakisphosphate 4-kinase activity

Catalysis of the reaction: ATP + 1D-myo-inositol hexakisphosphate = ADP + 4-diphospho-1D-myo-inositol (1,2,3,5,6)pentakisphosphate.


cellular response to amphetamine

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amphetamine stimulus. Amphetamines consist of a group of compounds related to alpha-methylphenethylamine.


thromboxane-A synthase activity

Catalysis of the reaction: prostaglandin H(2) = thromboxane A(2).


positive regulation of mechanoreceptor differentiation

Any process that activates or increases the frequency, rate or extent of mechanoreceptor differentiation.


neuronal action potential propagation

The propagation of an action potential along an axon, away from the soma.


maintenance of oocyte nucleus location involved in oocyte dorsal/ventral axis specification

Maintenance of the oocyte nucleus in a particular position within the cell during the establishment and maintenance of the axes of the oocyte. An example of this process is found In Drosophila melanogaster.


positive regulation of cellular response to oxidative stress

Any process that activates or increases the frequency, rate or extent of cellular response to oxidative stress.


lipid droplet formation

A process that results in the assembly, arrangement of constituent parts of a lipid droplet.


positive regulation of response to furfural

Any process that activates or increases the frequency, rate or extent of response to furfural.


propionyl-CoA carboxylase activity

Catalysis of the reaction: ATP + propanoyl-CoA + HCO3- = ADP + phosphate + (S)-methylmalonyl-CoA.


chloride ion binding

Binding to a chloride ion (Cl-).


protein deglutarylation

The removal of a glutaryl group (CO-CH2-CH2-CH2-CO) from a residue in a peptide or protein.


negative regulation of acetylcholine biosynthetic process

Any process that stops, prevents or reduces the frequency, rate or extent of acetylcholine biosynthetic process.


salicylic acid binding

Binding to salicylic acid.


N-terminal peptidyl-proline methylation

The methylation of the N-terminal proline of proteins.


proximal/distal pattern formation involved in metanephric nephron development

The regionalization process in which specific areas of cell differentiation are determined along a proximal/distal axis of a nephron in the metanephros. The proximal/distal axis is defined by a line that runs from the center of the kidney (proximal end) outward (distal end).


Catalysis of the reaction: (R)-pantolactone + NADP+ = 2-dehydropantolactone + NADPH + H+.


diacylglyceride transfer activity

Directly binding to diacylglyceride and delivering it either to an acceptor molecule or to a specific location.


oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen

Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from NADH or NADPH and one other donor, and one atom of oxygen is incorporated into one donor.


epithelial cell morphogenesis

The change in form that occurs when an epithelial cell progresses from its initial formation to its mature state.


aspartic endopeptidase activity, intramembrane cleaving

Catalysis of the hydrolysis of nonterminal peptide bonds in a polypeptide chain, occurring within a membrane.


corticotrophin-releasing factor receptor activity

Combining with the corticotrophin-releasing factor family of ligands, including the urocortins, to initiate a change in cell activity.


positive regulation of striated muscle contraction

Any process that activates or increases the frequency, rate or extent of striated muscle contraction.


angular vestibuloocular reflex

A vestibular reflex by which a response to an angular acceleration stimulus begins with an afferent nerve impulse from a receptor in the semi-circular canal and ends with the compensatory action of eye muscles. Signaling never reaches a level of consciousness.


effector-mediated induction of programmed cell death in host

A symbiont process in which a molecule secreted by the symbiont activates a programmed cell death pathway in the host to suppress the host innate immune response. The host is defined as the larger of the organisms involved in a symbiotic interaction.


regulation of haustorium mother cell formation

Any process that modulates the frequency, rate or extent of symbiont haustorium mother cell formation. The host is defined as the larger of the organisms involved in a symbiotic interaction.


Removes phosphatidylethanolamine from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle.


positive regulation of filamentous growth of a population of unicellular organisms in response to neutral pH

Any process that activates or increases the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to neutral pH.


negative regulation of membrane depolarization during AV node cell action potential

Any process that stops, prevents or reduces the frequency, rate or extent of membrane depolarization during AV node cell action potential.


circadian sleep/wake cycle process

A behavioral process involved in the cycle from wakefulness through an orderly succession of sleep states and stages that occurs on an approximately 24 hour rhythm.


ceramide 1-phosphate binding

Binding to ceramide 1-phosphate.


resolution of recombination intermediates

The cleavage and rejoining of intermediates, such as Holliday junctions, formed during DNA recombination to produce two intact molecules in which genetic material has been exchanged.


histone H3R2 demethylase activity

Catalysis of the removal of the methyl group from a modified arginine residue at position 2 of the histone H3 protein. This is a dioxygenase reaction that is dependent on Fe(II) and 2-oxoglutarate.


transforming growth factor beta3 production

The appearance of transforming growth factor-beta3 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


antigen processing and presentation of peptide antigen via MHC class Ib

The process in which an antigen-presenting cell expresses peptide antigen in association with an MHC class Ib protein complex on its cell surface. The peptide antigen may originate from an endogenous or exogenous protein. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E family.


cellular response to cyanide

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cyanide stimulus.


ventricular cardiac myofibril assembly

The process whose specific outcome is the progression of the ventricular cardiac myofibril over time, from its formation to the mature structure. A cardiac myofibril is a myofibril specific to cardiac muscle cells.


pollination

The cascade of biological processes occurring in plants beginning when the pollen lands on the female reproductive organs of a plant and continuing up to, but not including, fertilization, as defined by sperm-egg cell fusion.


protein-DNA-RNA complex remodeling

The acquisition, loss, or modification of macromolecules within a protein-DNA-RNA complex, resulting in the alteration of an existing complex.


involution involved in gastrulation with mouth forming second

The inturning of an epithelial sheet over the basal surface of an outer layer involved in deuterostomic gastrulation.


norsolorinate anthrone synthase activity

Catalysis of the reaction: 7 malonyl-CoA + 5 H+ + a hexanoyl-[acyl-carrier-protein] = norsolorinate anthrone + 7 coenzyme A + 7 carbon dioxide + 2 H2O + a holo-[acyl-carrier protein].


chloride peroxidase activity

Catalysis of the reaction: 2 R-H + 2 chloride + H2O2 = 2 R-Cl + 2 H2O.


positive regulation of methanofuran metabolic process

Any process that activates or increases the frequency, rate or extent of methanofuran metabolic process.


cellular response to tetrahydrofolate

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tetrahydrofolate stimulus.


Catalysis of the reaction: CTP + 2,3-di-O-geranylgeranyl-sn-glycero-1-phosphate = CDP-2,3-di-O-geranylgeranyl-sn-glycerol.


thiamine triphosphate phosphatase activity

Catalysis of the reaction: H2O + thiamine triphosphate = thiamine diphosphate + H+ + phosphate.


blasticidin-S deaminase activity

Catalysis of the reaction: blasticidin S + H2O = deaminohydroxyblasticidin S + NH3.


cysteine-type endopeptidase activity involved in apoptotic signaling pathway

Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile, and contributing to the apoptotic signaling pathway.


bract formation

The process that gives rise to a bract. This process pertains to the initial formation of a structure from unspecified parts. A bract is a leaf, usually different in form from the foliage leaves, subtending a flower or inflorescence.


Catalysis of the hydrolysis of (1->4)-beta-D-glucosidic links in oligoxyloglucans so as to remove successive isoprimeverose (i.e. alpha-xylo-1,6-beta-D-glucosyl-) residues from the non-reducing chain ends.


embryonic heart tube elongation

The developmental growth that results in the increase in length of the embryonic heart tube. The embryonic heart tube is an epithelial tube that will give rise to the mature heart.


protein-N(PI)-phosphohistidine-trehalose phosphotransferase system transporter activity

Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + trehalose(out) = protein histidine + trehalose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.


flavonoid phytoalexin catabolic process

The chemical reactions and pathways resulting in the breakdown of flavonoid phytoalexins, a group of water-soluble phenolic derivatives containing a flavan skeleton, which possess antibiotic activity and are produced by plant tissues in response to infection.


detection of reduced oxygen by aortic body chemoreceptor signaling

The process in which information about the levels of oxygen are received and are converted to a molecular signal by chemoreceptors in an aortic body.


4-hydroxycoumarin biosynthetic process

The chemical reactions and pathways resulting in the formation of 4-hydroxycoumarin.


dGMP catabolic process

The chemical reactions and pathways resulting in the breakdown of dGMP, deoxyguanosine monophosphate (2'-deoxyguanosine 5'-phosphate).


posterior lateral line neuromast deposition

The process in which a migrating neuromast primordium deposits clusters of undifferentiated cells (proneuromasts) along its migratory path in the developing posterior lateral line.


cyclic photosynthetic phosphorylation

A photosynthetic phosphorylation process in which ATP synthesis is driven by a proton gradient generated across the thylakoid membrane. Involves only photosystem I.


metanephric podocyte cell fate commitment

The process in which the developmental fate of a cell becomes restricted such that it will develop into a metanephric glomerular visceral epithelial cell. A metanephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the metanephros.


megakaryocyte differentiation

The process in which a myeloid precursor cell acquires specializes features of a megakaryocyte.


regulation of epiboly involved in gastrulation with mouth forming second

Any process that modulates the frequency, rate or extent of epiboly involved in gastrulation with mouth forming second.


cell migration involved in mammary placode formation

The orderly movement of epithelial cells within the mammary line that contributes to the formation of the mammary placode.


asparaginyl-tRNAAsn biosynthesis via transamidation

A tRNA aminoacylation process in which asparaginyl-tRNAAsn is formed by a tRNA-dependent two-step pathway. In the first step a non-discriminating aspartyl-tRNA synthetase generates the misacylated L-aspartyl-tRNAAsn species, and in the second step it is amidated to the correctly charged L-asparaginyl-tRNAAsn by the heterotrimeric aspartyl-tRNAAsn amidotransferase.


The series of molecular signals initiated by interleukin-20 binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.


Catalysis of the reaction: (R)-1-aminopropan-2-ol + NAD+ = aminoacetone + H+ + NADH.


RNA polymerase III general transcription initiation factor activity

A general transcription initiation factor activity that contributes to transcription start site selection and transcription initiation of genes transcribed by RNA polymerase III. Factors required for RNA polymerase III transcription initiation include TFIIIA, TFIIIB and TFIIIC. RNA polymerase III transcribes genes encoding short RNAs, including tRNAs, 5S rRNA, U6 snRNA, the short ncRNA component of RNases P, the mitochondrial RNA processing (MRP) RNA, the signal recognition particle SRP RNA, and in higher eukaryotes a number of micro and other small RNAs, though there is some variability across species as to whether a given small noncoding RNA is transcribed by RNA polymerase II or RNA polymerase III.


tumor necrosis factor superfamily cytokine production

The appearance of any member of the TNF superfamily due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


methanofuran metabolic process

The chemical reactions and pathways involving a methanofuran.


response to singlet oxygen

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a singlet oxygen stimulus. Singlet oxygen is a dioxygen (O2) molecule in which two 2p electrons have similar spin. Singlet oxygen is more highly reactive than the form in which these electrons are of opposite spin, and it is produced in mutant chloroplasts lacking carotenoids and by leukocytes during metabolic burst.


Catalysis of the reaction: acetyl-CoA + an alpha-2,8-linked polymer of sialic acid = CoA + polysialic acid acetylated at O-7 or O-9.


mitochondrial tRNA processing

The process in which a pre-tRNA molecule is converted to a mature tRNA, ready for addition of an aminoacyl group, in the mitochondrion.


quinate catabolic process

The chemical reactions and pathways resulting in the breakdown of quinate, the anion of quinic acid.


O-glycan processing, core 7

The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form the core 7 O-glycan structure, GalNAc-alpha-(1->6)-GalNAc.


cranial nerve structural organization

The process that contributes to the act of creating the structural organization of the cranial nerves. This process pertains to the physical shaping of a rudimentary structure. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions.


long-term synaptic depression

A process that modulates synaptic plasticity such that synapses are changed resulting in the decrease in the rate, or frequency of synaptic transmission at the synapse.


cellular response to desiccation

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a desiccation stimulus, extreme dryness resulting from the prolonged deprivation of water.


steviol 13-O glucosyltransferase activity

Catalysis of the reaction: steviol + UDP-alpha-D-glucose = steviolmonoside + UDP + H+.


skeletal system morphogenesis

The process in which the anatomical structures of the skeleton are generated and organized.


mesonephric tubule formation

The developmental process pertaining to the initial formation of a mesonephric tubule from unspecified parts. A mesonephric tubule is an epithelial tube that is part of the mesonephros.


diphenyl ether 2,3-dioxygenase activity

Catalysis of the reaction: diphenyl ether + O2 = 2,3-dihydroxydiphenyl ether.


Catalysis of the reaction: (7S)-salutaridinol + acetyl-CoA = (7S)-O-acetylsalutaridinol + CoA.


positive regulation of mitotic cell cycle phase transition

Any process that activates or increases the frequency, rate or extent of mitotic cell cycle phase transition.


cellular response to nitrosative stress

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrosative stress stimulus. Nitrosative stress is a state often resulting from exposure to high levels of nitric oxide (NO) or the highly reactive oxidant peroxynitrite, which is produced following interaction of NO with superoxide anions.


Catalysis of the reaction: palmitoyl-CoA + mucus glycoprotein = CoA + O-palmitoylglycoprotein.


positive regulation of endothelial cell chemotaxis

Any process that activates or increases the frequency, rate or extent of endothelial cell chemotaxis.


sterol-4-alpha-carboxylate 3-dehydrogenase (decarboxylating) activity

Catalysis of the reaction: NAD(P)+ + 3-beta-hydroxy-4-alpha-methyl-5-alpha-cholest-7-ene-4-beta-carboxylate = NAD(P)H + H+ + CO2 + 4-alpha-methyl-5-alpha-cholest-7-en-3-one.


cellular response to erythropoietin

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an erythropoietin stimulus.


peptidyl-serine ADP-deribosylation

The removal of ADP-ribose from ADP-ribosylserine.


Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: citrate(out) + H+(out) = citrate(in) + H+(in).


positive regulation of hepatic stellate cell contraction

Any process that activates or increases the frequency, rate or extent of hepatic stellate cell contraction.


xanthophyll catabolic process

The chemical reactions and pathways resulting in the breakdown of xanthophylls, oxygen-containing carotenoids.


interleukin-12 receptor activity

Combining with interleukin-12 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


benzo(a)pyrene 7,8-dioxygenase activity

Catalysis of the reaction: benzo(a)pyrene + O2 = benzo(a)pyrene-cis-7,8-dihydrodiol.


paraxial mesoderm morphogenesis

The process in which the anatomical structures of the paraxial mesoderm are generated and organized.


protein localization to centriolar satellite

A process in which a protein is transported to, or maintained in, a location within a centriolar satellite.


regulation of type 2 immune response

Any process that modulates the frequency, rate, or extent of a type 2 immune response.


detection of steroid hormone stimulus

The series of events by which a steroid hormone stimulus is received by a cell and converted into a molecular signal.


D-leucine biosynthetic process

The chemical reactions and pathways resulting in the formation of D-leucine.


regulation of cardiac muscle contraction by calcium ion signaling

Any process that modulates the frequency, rate or extent of cardiac muscle contraction by changing the calcium ion signals that trigger contraction.


epithelial cell migration involved in metanephric distal tubule morphogenesis

The orderly movement of epithelial cells within a renal tubule that contributes to metanephric distal tubule morphogenesis.


cellular response to corticosteroid stimulus

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticosteroid hormone stimulus. A corticosteroid is a steroid hormone that is produced in the adrenal cortex. Corticosteroids are involved in a wide range of physiologic systems such as stress response, immune response and regulation of inflammation, carbohydrate metabolism, protein catabolism, blood electrolyte levels, and behavior. They include glucocorticoids and mineralocorticoids.


establishment of planar polarity of embryonic epithelium

Coordinated organization of groups of cells in the plane of an embryonic epithelium, such that they all orient to similar coordinates.


retinal cone cell apoptotic process

Any apoptotic process in a retinal cone cell, one of the two photoreceptor cell types of the vertebrate retina.


blasticidin S biosynthetic process

The chemical reactions and pathways resulting in the formation of blasticidin S.


regulation of amine metabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform amines.


negative regulation of acute inflammatory response to antigenic stimulus

Any process that stops, prevents, or reduces the frequency, rate, or extent of an acute inflammatory response to an antigenic stimulus.


formate dehydrogenase (NAD+) activity

Catalysis of the reaction: formate + NAD+ = CO2 + NADH.


osmoregulated periplasmic glucan catabolic process

The chemical reactions and pathways resulting in the breakdown of osmoregulated periplasmic glucan.


progesterone biosynthetic process

The chemical reactions and pathways resulting in the formation of progesterone, a steroid hormone produced in the ovary which prepares and maintains the uterus for pregnancy. Also found in plants.


ribose 1-dehydrogenase (NADP+) activity

Catalysis of the reaction: H2O + NADP+ + ribofuranose = D-ribonate + 2 H+ + NADPH.


right ventricular trabecular myocardium morphogenesis

The process in which the anatomical structures of the right ventricular myocardium are generated and organized.


oxidoreductase activity, acting on diphenols and related substances as donors, NAD or NADP as acceptor

Catalysis of an oxidation-reduction (redox) reaction in which a diphenol, or related compound, acts as a hydrogen or electron donor and reduces NAD or NADP.


water-soluble vitamin catabolic process

The chemical reactions and pathways resulting in the breakdown of any of a diverse group of vitamins that are soluble in water.


cellular defense response

A defense response that is mediated by cells.


regulation of TORC1 signaling

Any process that modulates the frequency, rate or extent of TORC1 signaling.


methanesulfonate monooxygenase activity

Catalysis of the reaction: methanesulfonate + NADH + H+ + O2 = formaldehyde + NAD+ + sulfite + H2O.


ganglioside biosynthetic process

The chemical reactions and pathways resulting in the formation of ceramide oligosaccharides carrying in addition to other sugar residues, one or more sialic acid residues.


enterobactin binding

Binding to enterobactin.


regulation of aeciospore formation

Any process that modulates the frequency, rate or extent of aeciospore formation, a process in which a dikaryotic spore of typically a rust fungus is produced in an aecium.


response to hypobaric hypoxia

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension combined with low atmospheric pressure. Hypoxia is defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95% and hypobaric is defined as atmospheric pressure below 0.74 atm (greater than 2,500 m above sea level).


lysine catabolic process

The chemical reactions and pathways resulting in the breakdown of lysine, 2,6-diaminohexanoic acid.


sporulation

The process whose specific outcome is the progression of a spore over time, from its initiation to the mature structure. A spore is a structure that can be used for dissemination, for survival of adverse conditions because of its heat and dessication resistance, and/or for reproduction.


leukotriene B4 catabolic process

The chemical reactions and pathways resulting in the breakdown of leukotriene B4, a leukotriene composed of (6Z,8E,10E,14Z)-eicosatetraenoic acid having (5S)- and (12R)-hydroxy substituents.


pullulanase activity

Catalysis of the hydrolysis of (1,6)-alpha-D-glucosidic linkages in pullulan (a linear polymer of alpha-(1,6)-linked maltotriose units) and in amylopectin and glycogen, and the a- and b-limit dextrins of amylopectin and glycogen.


Lewy body formation

The aggregation, arrangement and bonding together of a set of components to form a Lewy body.


ADP dimethylallyltransferase activity

Catalysis of the reaction: delta2-isopentenyl diphosphate + ADP = diphosphate + N6-(delta(2)-isopentenyl)adenosine 5'-diphosphate.


mismatch base pair DNA N-glycosylase activity

Catalysis of the removal of single bases present in mismatches by the cleavage the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apurinic/apyrimidinic (AP) site.


ciliary basal body organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a ciliary basal body, a short cylindrical array of microtubules and associated proteins found at the base of a eukaryotic cilium (also called flagellum).


positive regulation of gamma-aminobutyric acid uptake involved in transmission of nerve impulse

Any process that activates, maintains or increases the frequency, rate or extent of the directed movement of gamma-aminobutyric acid (GABA, 4-aminobutyrate) into a neuron or glial cell.


female germ-line stem cell population maintenance

The process by which an organism or tissue maintains a population of female germ-line stem cells.


CDP-diacylglycerol metabolic process

The chemical reactions and pathways involving CDP-diacylglycerol, CDP-1,2-diacylglycerol, a substance composed of diacylglycerol in glycosidic linkage with cytidine diphosphate. It is a common intermediate in phospholipid biosynthesis.


sn-1-glycerol-3-phosphate C16:0-DCA-CoA acyl transferase activity

Catalysis of the reaction: hexadecanedioyl-CoA + sn-glycerol 3-phosphate = coenzyme A + 1-C16:0-alpha,omega-dicarboxyl-2-lysophosphatidate.


regionalization involved in semicircular canal formation

The pattern specification process that results in the subdivision of the otic epithelium in space to define an area or volume in which cells will differentiate to give rise to the semicircular canals.


adenosylcobyric acid synthase (glutamine-hydrolyzing) activity

Catalysis of the reaction: 4 L-glutamine + adenosylcob(III)yrinate a,c-diamide + 4 ATP + 4 H2O = 4 L-glutamate + adenosylcobyrate + 4 ADP + 8 H+ + 4 phosphate.


response to puromycin

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a puromycin stimulus.


acridone synthase activity

Catalysis of the reaction: N-methylanthranilyl-CoA + 3 H+ + 3 malonyl-CoA = 1,3-dihydroxy-N-methylacridone + 3 CO2 + 4 CoA + H2O.


farnesol catabolic process

The chemical reactions and pathways resulting in the breakdown of the sesquiterpenoid alcohol farnesol, 3,7,11-trimethyl-2,6,10,dodecatrien-1-ol.


negative regulation of adult somatic muscle development

Any process that decreases the rate, frequency or extent of adult somatic muscle development.


allantoate transmembrane transporter activity

Enables the transfer of allantoate from one side of a membrane to the other. Allantoate is the end product of purine metabolism in mammals and some fish, formed form allantoin. It is widely distributed in plants as an important source of stored nitrogen.


RNA acetylation

The posttranscriptional addition of one or more acetyl groups to specific residues in an RNA molecule.


inner cell mass cell differentiation

The process in which a relatively unspecialized cell acquires specialized features of an inner cell mass cell.


Catalysis of the reaction: (S)-3-hydroxyacyl-CoA + NAD(P)+ = 3-oxoacyl-CoA + NAD(P)H + H+, where the acyl group is a long-chain fatty acid residue. A long-chain fatty acid is a fatty acid with a chain length between C13 and C22.


COP9 signalosome assembly

The aggregation, arrangement and bonding together of a set of components to form a COP9 signalosome.


Catalysis of the reaction: beta-alanine + S-adenosyl-L-methionine = H+ + N-methyl-beta-alanine + S-adenosyl-L-homocysteine.


negative regulation of microglial cell activation

Any process that stops, prevents or reduces the frequency, rate or extent of microglial cell activation.


mammary gland bud formation

The morphogenetic process in which a bud forms from the mammary placode. A mammary bud is bulb of epithelial cells that is distinct from the surrounding epidermis.


post-embryonic plant organ development

Development, taking place during the post-embryonic phase of a plant tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.


shoot organ boundary specification

The process in which the basal boundary between the stem and both vegetative and reproductive organs are established and maintained.


aminophosphonate metabolic process

The chemical reactions and pathways involving aminophosphonates, phosphonic acid derivatives that contain an amino group.


16-hydroxysteroid epimerase activity

Catalysis of the reaction: 16-alpha-hydroxysteroid = 16-beta-hydroxysteroid.


acetyl-CoA biosynthetic process from acetate

The chemical reactions and pathways resulting in the formation of acetyl-CoA from acetate, either directly or via acetylphosphate.


3-deoxyglucosone dehydrogenase activity

Catalysis of the reaction: 3-deoxyglucosone + H2O + NAD+ = 2-dehydro-3-deoxy-D-gluconate + 2 H+ + NADH.


Catalysis of the reaction: 2,4,4-trimethylpentanal + H2O = 2,4,4-trimethylpentanoate + 3 H+ + 2 e-.


The process of coupling arginine to arginyl-tRNA in a mitochondrion, catalyzed by arginyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.


hypotonic response

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a hypotonic environment, i.e. an environment with a lower concentration of solutes than the organism or cell.


oxidoreductase activity, acting on the CH-CH group of donors, iron-sulfur protein as acceptor

Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces an iron-sulfur protein.


cyanidin 3-O-glucoside 5-O glucosyltransferase (vanilloyl-glucose dependent) activity

Catalysis of the reaction: cyanidin 3-O-beta-D-glucoside betaine + 1-O-vanilloyl-beta-D-glucose <=> cyanin betaine + vanillate + H+.


zeaxanthin metabolic process

The chemical reactions and pathways involving zeaxanthin.


positive regulation of dauer larval development

Any process that increases the rate, frequency, or extent of dauer larval development, the process whose specific outcome is the progression of the dauer larva over time, through the facultative diapause of the dauer (enduring) larval stage, with specialized traits adapted for dispersal and long-term survival, with elevated stress resistance and without feeding.


Catalysis of the reaction: D-glucarate + sinapoyl-CoA = 2-O-sinapoyl-D-glucarate + CoA.


CYP79F1 tetrahomomethionine monooxygenase activity

Catalysis of the reaction: 2 H+ + tetrahomomethionine + 2 O2 + 2 NADPH <=> 3 H2O + carbon dioxide + 2 NADP + 7-methylthioheptanaldoxime.


protein C-terminal carboxyl O-methyltransferase activity

Catalysis of the transfer of a methyl group to the oxygen atom of a carboxyl group at the C-terminal of a protein.


specification of mesonephric nephron tubule identity

The process in which the tubules arranged along the proximal/distal axis of the mesonephric nephron acquire their identity.


aminoglycan metabolic process

The chemical reactions and pathways involving aminoglycans, any polymer containing amino groups that consists of more than about 10 monosaccharide residues joined to each other by glycosidic linkages.


Catalysis of the reaction: L-tyrosine + 2-oxoglutarate = 4-hydroxyphenylpyruvate + L-glutamate.


nucleus localization

Any process in which the nucleus is transported to, and/or maintained in, a specific location within the cell.


hydroxymethylfurfural reductase (NADPH) activity

Catalysis of the reaction: 5-hydroxymethylfurfural + NADPH + H+ = 2,5-bis-hydroxymethylfuran + NADP+.


U4atac snRNA binding

Binding to a U4atac small nuclear RNA (U4atac snRNA).


cholesterol oxidase activity

Catalysis of the reaction: cholesterol + O2 = cholest-5-en-3-one + H2O2.


Any process involved in the maintenance of an internal steady state at the level of the multicellular organism.


mannose transmembrane transporter activity

Enables the transfer of mannose from one side of a membrane to the other. Mannose is the aldohexose manno-hexose, the C-2 epimer of glucose. The D-(+)-form is widely distributed in mannans and hemicelluloses and is of major importance in the core oligosaccharide of N-linked oligosaccharides of glycoproteins.


glycolytic fermentation via PFOR pathway

The glycolytic fermentation beginning with the anaerobic conversion of glucose to pyruvate by the glycolytic pathway, continuing with pyruvate:ferredoxin oxidoreductase (PFOR) activity. This pathway is found in strict anaerobes such as Clostridia species.


epiboly

The expansion of one cell sheet over other cells or yolk.


regulation of cardiac muscle cell action potential

Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a cardiac muscle cell. This typically occurs via modulation of the activity or expression of voltage-gated ion channels.


Catalysis of the reaction: 4-hydroxy-2-oxoglutarate = pyruvate + glyoxylate.


histone propionyltransferase activity

Catalysis of the reaction: propionyl-CoA + histone = CoA + propionyl-histone.


Catalyzes the reaction: N,N-Dihydroxy-L-tryptophan = Indole-3-acetaldehyde oxime + CO2 + H2O.


alanine transmembrane transporter activity

Enables the transfer of alanine from one side of a membrane to the other. Alanine is 2-aminopropanoic acid.


histone H4R3 demethylase activity

Catalysis of the removal of the methyl group from a modified arginine residue at position 3 of the histone H4 protein. This is a dioxygenase reaction that is dependent on Fe(II) and 2-oxoglutarate.


Catalysis of the reaction: H+ + eriodictyol + NADPH + O2 <=> 2-(3,4-dihydroxyphenyl)-5-hydroxy-4-oxo-4H-chromen-7-olate luteolin-7-olate(1-) + NADP + 2 H2O.


metanephric glomerular parietal epithelial cell differentiation

The process in which a relatively unspecialized cell acquires specialized features of a metanephric glomerular parietal epithelial cell. Metanephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport.


2-dehydropantoate 2-reductase activity

Catalysis of the reaction: (R)-pantoate + NADP+ = 2-dehydropantoate + H+ + NADPH.


regulation of cholesterol metabolic process

Any process that modulates the rate, frequency, or extent of cholesterol metabolism, the chemical reactions and pathways involving cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.


Catalysis of the reaction: 3,5-dihydroxyanisole + S-adenosyl-L-methionine = H+ + 3,5-dimethoxyphenol + S-adenosyl-L-homocysteine.


negative regulation of muscle hypertrophy

Any process that stops, prevents, or reduces the frequency, rate, or extent of muscle hypertrophy.


synephrine dehydratase activity

Catalysis of the reaction: synephrine = (4-hydroxyphenyl)acetaldehyde + methylammonium.


chemosensory behavior

Behavior that is dependent upon the sensation of chemicals.


regulation of interleukin-35-mediated signaling pathway

Any process that modulates the rate, frequency or extent of an interleukin-35-mediated signaling pathway.


apoptotic process involved in outflow tract morphogenesis

Any apoptotic process that contributes to the shaping of the outflow tract. The outflow tract is the portion of the heart through which blood flows into the arteries.


positive regulation of epithelial to mesenchymal transition

Any process that increases the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition is where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.


Catalysis of the reaction: trans-9R,10R-dihydrodiolphenanthrene + 2 X-SO3(-) = 2 HX + phenanthrene-9,10-dihydrodiolsulfate conjugate.


vestibulospinal tract morphogenesis

Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the vestibular nucleus of the pons towards target cells in the spinal cord.


3-dehydroshikimate dehydratase activity

Catalysis of the reaction: 3-dehydroshikimate = 3,4-dihydroxybenzoate + H2O. 3,4-dihydroxybenzoate is also known as protocatechuate.


pollen-stigma interaction

The interactions (or cell to cell communication) that occur between the pollen grain (male gametophyte) and the stigmatic tissues of the female sporophyte after the pollen reaches the stigmatic papillae.


malonate catabolic process

The chemical reactions and pathways resulting in the breakdown of malonate, the propanedioate ion.


adult behavior

Behavior in a fully developed and mature organism.


vasoactive intestinal polypeptide receptor activity

Combining with vasoactive intestinal polypeptide to initiate a change in cell activity.


negative regulation of mitotic centrosome separation

Any process that stops, prevents, or reduces the frequency, rate or extent of centrosome separation.


pantoate 4-dehydrogenase activity

Catalysis of the reaction: (R)-pantoate + NAD+ = (R)-4-dehydropantoate + H+ + NADH.


positive regulation of myotube cell migration

Any process that activates, maintains or increases the frequency, rate or extent of myotube cell migration.


response to magnesium ion

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a magnesium ion stimulus.


mesonephros morphogenesis

The process in which the anatomical structures of the mesonephros are generated and organized.


establishment of endothelial barrier

The establishment of a barrier between endothelial cell layers, such as those in the brain, lung or intestine, to exert specific and selective control over the passage of water and solutes, thus allowing formation and maintenance of compartments that differ in fluid and solute composition.


voltage-gated channel activity

Enables the transmembrane transfer of a solute by a channel whose open state is dependent on the voltage across the membrane in which it is embedded.


Catalysis of the reaction: UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysine + ATP + D-alanyl-D-alanine = phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine + ADP.


protein localization to nuclear body

A process in which a protein is transported to, or maintained in, a location within a nuclear body.


regulation of stomatal movement

Any process that modulates the frequency, rate or extent of stomatal movement.


Catalysis of the reaction: S-adenosyl-L-methionine + isoflavone = S-adenosyl-L-homocysteine + 4'-O-methylisoflavone.


benzenesulfonate dioxygenase activity

Catalysis of the reaction: toluene-4-sulfonate + NADH + O2 + H+ = NAD+ + HSO3(-) + 4-methylcatechol.


response to exogenous dsRNA

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an exogenous double-stranded RNA stimulus.


dendritic cell homeostasis

The process of regulating the proliferation and elimination of dendritic cells such that the total number of dendritic cells within a whole or part of an organism is stable over time in the absence of an outside stimulus.


3-hydroxybutyryl-CoA thiolase activity

Catalysis of the reaction: 3-hydroxy-5-oxohexanoyl-CoA + CoASH = 3-hydroxybutyryl-CoA + acetyl-CoA.


negative regulation of hippo signaling

Any process that stops, prevents, or reduces the frequency, rate or extent of hippo signaling.


The process of coupling aspartate to aspartyl-tRNA in a mitochondrion, catalyzed by aspartyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.


Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 2,3,7,8-tetrachlorodibenzodioxine stimulus.


The chemical reactions and pathways involving 4-carboxy-4'-sulfoazobenzene, a sulfonated azo compound synthesized by nitro-amine condensation from sulfanilic acid and 4-nitrobenzoic acid.


protein-transporting ATPase activity

Primary active carrier-mediated transport of a protein across a membrane, driven by the hydrolysis of the diphosphate bond of inorganic pyrophosphate, ATP, or another nucleoside triphosphate. The transport protein may or may not be transiently phosphorylated, but the substrate is not phosphorylated.


sulfur-containing amino acid secondary active transmembrane transporter activity

Enables the transfer of sulfur-containing amino acid from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters.


fatty aldehyde dehydrogenase activity

Catalysis of the reaction: NAD(1-) + H2O + a fatty aldehyde <=> NADH(2-) + 2 H+ + a fatty acid.


protein galactosylation

The addition of a galactose molecule to a protein amino acid.


paromomycin metabolic process

The chemical reactions and pathways involving paromomycin.


inulosucrase activity

Catalysis of the reaction: sucrose + 2,1-beta-D-fructosyl(n) = glucose + 2,1-beta-D-fructosyl(n+1).


medial fin development

The process whose specific outcome is the progression of a medial fin over time, from its formation to the mature structure.


germ-line stem cell population maintenance

Any process by which an organism or tissue maintains a population of germ-line stem cells.


gluconokinase activity

Catalysis of the reaction: D-gluconate + ATP = 6-phospho-D-gluconate + ADP + 2 H+.


positive regulation of toll-like receptor 7 signaling pathway

Any process that activates or increases the frequency, rate, or extent of toll-like receptor 7 signaling pathway.


trioxoheptanoate hydrolase activity

Catalysis of the reaction: 2,4,6-trioxoheptanoate + H2O = acetylpyruvate + acetate.


cephalosporin metabolic process

The chemical reactions and pathways involving a cephalosporin, any of large class of tetracyclic triterpene broad-spectrum antibiotics similar both chemically and in their mode of action to penicillin, first isolated from the culture filtrates of mediterranean fungus acremonium (cephalosporium acremonium), and effective against gram-positive bacteria.


cell development

The cellular developmental process in which a specific cell progresses from an immature to a mature state. Cell development start once cell commitment has taken place.


ornithine racemase activity

Catalysis of the reaction: L-ornithine = D-ornithine.


regulation of SMAD protein signal transduction

Any process that modulates the rate, frequency or extent of SMAD protein signal transduction.


ryanodine-sensitive calcium-release channel activity involved in regulation of postsynaptic cytosolic calcium levels

Any ryanodine-sensitive calcium-release channel activity that is involved in regulation of postsynaptic cytosolic calcium ion concentration.


cell wall modification involved in multidimensional cell growth

The series of events resulting in chemical or structural changes to existing cell walls and contribute to multidimensional cell growth.


fumarylacetoacetase activity

Catalysis of the reaction: 4-fumarylacetoacetate + H2O = acetoacetate + fumarate + H+.


dimethylallyl diphosphate biosynthetic process

The chemical reactions and pathways resulting in the formation of dimethylallyl diphosphate.


Catalysis of the reaction: 3-hydroxybenzoate + H+ + NADPH + O2 = 3,4-dihydroxybenzoate + H2O + NADP+.


Catalysis of the reaction: 1-phenanthrol + glucose = 1-phenanthryl-beta-D-glucopyranoside + H2O.


pantoate-beta-alanine ligase activity

Catalysis of the reaction: ATP + (R)-pantoate + beta-alanine = AMP + diphosphate + (R)-pantothenate.


myoblast maturation

A developmental process, independent of morphogenetic (shape) change, that is required for a myoblast to attain its fully functional state. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.


muconolactone delta-isomerase activity

Catalysis of the reaction: (S)-muconolactone = (4,5-dihydro-5-oxofuran-2-yl)-acetate.


envenomation resulting in positive regulation of acid-sensing ion channel activity in another organism

A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant positive regulation in the activity of an acid-sensing ion channel (ASIC) in the bitten organism.


negative regulation of secondary metabolite biosynthetic process

Any process that stops, prevents or reduces the frequency, rate or extent of secondary metabolite biosynthetic process.


striated muscle tissue development

The process whose specific outcome is the progression of a striated muscle over time, from its formation to the mature structure. Striated muscle contain fibers that are divided by transverse bands into striations, and cardiac and skeletal muscle are types of striated muscle. Skeletal muscle myoblasts fuse to form myotubes and eventually multinucleated muscle fibers. The fusion of cardiac cells is very rare and can only form binucleate cells.


acylglycerol acyl-chain remodeling

Remodeling the acyl chains of an acylglycerol, through sequential deacylation and re-acylation reactions, to generate an acylglycerol containing different types of fatty acid acyl chains.


protein storage vacuole organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a protein storage vacuole, a storage vacuole that contains a lytic vacuole.


regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation

Any process that modulates the frequency, rate or extent of differentiation of CD4-positive, CD25-positive, alpha-beta regulatory T cells.


adaptation to pheromone regulating conjugation with mutual genetic exchange

In organisms that undergo conjugation without cellular fusion, the process resulting in desensitization following exposure to pheromone stimulus that act to down-regulate further stimulation or block initial conjugation responses.


cyclic GMP-AMP synthase activity

Catalysis of the reaction: ATP + GTP = 2 diphosphate + cyclic GMP-AMP.


protein octanoylation

The modification of a protein amino acid by formation of an ester or amide with octanoic acid.


signal transduction involved in cellular response to ammonium ion

Any signal transduction that is involved in cellular response to ammonium ion.


L-asparagine metabolic process

The chemical reactions and pathways involving L-asparagine, (2S)-2-amino-3-carbamoylpropanoic acid.


hydrogen metabolic process

The chemical reactions and pathways involving H2 (dihydrogen).


Catalysis of the reaction: N-acetylphenylethylamine + H2O = acetate + phenylethylamine.


Catalysis of the reaction: dimethylallyl diphosphate + L-tryptophan = diphosphate + 4-(3-methylbut-2-enyl)-L-tryptophan.


lymph gland development

The process whose specific outcome is the progression of the lymph gland over time, from its formation to the mature structure. The lymph gland is one of the sites of hemocyte differentiation. It consists of three to six bilaterally paired lobes that are attached to the cardioblasts during larval stages, and it degenerates during pupal stages.


oligodendrocyte development

The process aimed at the progression of an oligodendrocyte over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. An oligodendrocyte is a type of glial cell involved in myelinating the axons in the central nervous system.


cellular response to gonadotropin-releasing hormone

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gonadotropin-releasing hormone stimulus. Gonadotropin-releasing hormone (GnRH) is a peptide hormone responsible for the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the anterior pituitary. GnRH is synthesized and released by the hypothalamus.


translation repressor activity, non-nucleic acid binding

Antagonizes the ribosome-mediated translation of mRNA into a polypeptide but does not bind directly to nucleic acid.


biphenyl metabolic process

The chemical reactions and pathways involving biphenyl, a toxic aromatic hydrocarbon used as a heat transfer agent, as a fungistat in packaging citrus fruits and in plant disease control. Biphenyl can be chlorinated with 1-10 chlorine molecules to form polychlorinated biphenyls (PCBs).


lymphocyte adhesion to endothelial cell of high endothelial venule

The attachment of a lymphocyte to an endothelial cell of a high endothelial venule (HEV) via adhesion molecules. A HEV cell is an endothelial cell that is cuboidal, expresses leukocyte-specific receptors, and allows for passage of lymphocytes into bloodstream.


negative regulation of intracellular mRNA localization

Any process that stops, prevents or reduces the frequency, rate or extent of intracellular mRNA localization.


Purkinje myocyte to ventricular cardiac muscle cell communication

The process that mediates interactions between a Purkinje myocyte and its surroundings that contributes to the process of the Purkinje myocyte communicating with a ventricular cardiac muscle cell in cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.


formation of syncytium involving giant cell for nutrient acquisition

The assembly of a syncytium, a multi-nucleate and physiologically active aggregation of fused root cells induced by a symbiotic nematode in a plant host. The syncytium exclusively provides the nematode with nourishment during its sedentary life, for the purpose of obtaining nutrients from its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.


dichotomous subdivision of prostate epithelial cord terminal unit

The process in which a prostate epithelial cord bifurcates at its end.


regulation of SA node cell action potential

Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in an SA node cardiac myocyte. This typically occurs via modulation of the activity or expression of voltage-gated ion channels.


protein phosphate-linked glycosylation

The glycosylation of peptidyl-amino acids through a phosphoester bond forming, for example, GlcNAc-alpha-1-P-Ser residues.


embryonic meristem initiation

Initiation of a region of tissue in a plant embryo that is composed of one or more undifferentiated cells capable of undergoing mitosis and differentiation.


butyrate metabolic process

The chemical reactions and pathways involving any butyrate, the anions of butyric acid (butanoic acid), a saturated, unbranched aliphatic acid.


ACP phosphopantetheine attachment site binding

Binding to the attachment site of the phosphopantetheine prosthetic group of an acyl carrier protein (ACP).


regulation of iron export across plasma membrane

Any process that modulates the frequency, rate or extent of export of iron ions from inside of a cell, across the plasma membrane and into the extracellular region.


positive regulation of lactose biosynthetic process

Any process that activates or increases the frequency, rate or extent of lactose biosynthetic process.


regulation of synaptic vesicle cycle

Any process that modulates the frequency, rate or extent of the synaptic vesicle cycle.


regulation of peroxisome proliferator activated receptor signaling pathway

Any process that modulates the frequency, rate or extent of the peroxisome proliferator activated receptor signaling pathway.


S-shaped body morphogenesis

The process in which the S-shaped body is generated and organized. The S-shaped body is the successor of the comma-shaped body that contributes to the morphogenesis of the nephron.


mevalonate transmembrane transporter activity

Enables the transfer of mevalonate from one side of a membrane to the other. Mevalonate is the anion of mevalonic acid; its (R)-enantiomer is a strategic intermediate derived from hydroxymethylglutaryl-CoA in the biosynthesis of polyprenyl compounds.


azole transmembrane transporter activity

Enables the directed movement of azoles, heterocyclic compound found in many biologically important substances, from one side of a membrane to the other.


phosphinothricin biosynthetic process

The chemical reactions and pathways resulting in the formation of phosphinothricin.


L-proline transmembrane transporter activity

Enables the transfer of L-proline from one side of a membrane to the other. L-proline is pyrrolidine-2-carboxylic acid.


dimethylmalonate decarboxylase activity

Catalysis of the reaction: dimethylmalonate + H+ = isobutyrate + CO2.


Catalysis of the reaction: dTDP-6-deoxy-beta-L-mannose + N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octacis-decaprenol <=> dTDP(3-) + alpha-L-Rhap-(1->3)-alpha-D-GlcpNAc-1-diphospho-trans,octacis-decaprenol + H+.


lactoferrin transmembrane transporter activity

Enables the transfer of lactoferrin from one side of a membrane to the other.


memory B cell differentiation

The process in which a B cell acquires the specialized features of a memory B cell. Memory B cells are cells that can respond rapidly to antigen re-exposure by production of high-affinity antibody.


antimicrobial peptide production

The synthesis or release of an antimicrobial peptide during an immune response, resulting in an increase in intracellular or extracellular levels. Such peptides may have protective properties against bacteria, fungi, viruses, or protozoa.


short-day photoperiodism

Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a day length that falls short of a particular duration known as the 'critical day length'. The critical day length varies between species. Although the term short-day is used, most species actually respond to the duration of the night, so that the response will occur when a period of darkness exceeds the number of hours defined by 24 hours minus the critical day length.


protein branching point deglutamylation

The removal of a branching point glutamate residue. A branching point glutamate connects a glutamate side chain to a gene-encoded glutamate residue.


tri-n-butyltin metabolic process

The chemical reactions and pathways involving tri-n-butyltin, an organometallic compound composed of three butyl chains attached to a tin atom. Tri-n-butyltin is used as an antifouling agent in ship bottom paints and can be toxic to many marine organisms.


Catalysis of the reaction: S-adenosyl-L-methionine + precorrin-4 = S-adenosyl-L-homocysteine + precorrin 5.


zinc potentiation of synaptic transmission, glycinergic

Any process that activates or increases the frequency, rate or extent of glycinergic synaptic transmission in the presence of zinc. Glycinergic synaptic transmission is the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glycine.


regulation of sexual sporulation resulting in formation of a cellular spore

Any process that modulates the frequency, rate or extent of the formation of cellular spores derived from the products of meiosis.


regulation of hormone metabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving any hormone.


oncostatin-M receptor activity

Combining with oncostatin-M and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


regulation of venous endothelial cell fate commitment

Any process that modulates the frequency, rate or extent of venous endothelial cell fate commitment.


vestibular receptor cell development

The process whose specific outcome is the progression of a vestibular receptor cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.


positive regulation of muscle hypertrophy

Any process that activates or increases the frequency, rate or extent of muscle hypertrophy.


transcription by RNA polymerase V

The synthesis of RNA from a DNA template by RNA polymerase V, originating at a Pol V-specific promoter.


somatic diversification of immune receptors

The somatic process allowing for the production of immune receptors whose specificity is not encoded in the germline genomic sequences.


galactose-specific flocculation

The non-sexual aggregation of single-celled organisms mediated by the binding of cell wall proteins on one cell to galactose residues on the other.


calcium-mediated signaling using extracellular calcium source

The series of molecular signals in which a cell uses calcium ions imported from an extracellular source to convert a signal into a response.


ephrin receptor signaling pathway

The series of molecular signals initiated by ephrin binding to its receptor, and ending with the regulation of a downstream cellular process, e.g. transcription.


regulation of neuronal synaptic plasticity

A process that modulates neuronal synaptic plasticity, the ability of neuronal synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers.


renal amino acid absorption

A renal system process in which amino acids are taken up from the collecting ducts, glomerulus and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures.


positive regulation of smooth muscle cell proliferation

Any process that activates or increases the rate or extent of smooth muscle cell proliferation.


CDP-abequose epimerase activity

Catalysis of the reaction: CDP-3,6-dideoxy-D-glucose = CDP-3,6-dideoxy-D-mannose.


neutrophic extracellular trap formation

The aggregation, arrangement and bonding together of a set of components to form a neutrophil extracellular trap, a network of extracellular fibers primarily composed of DNA from neutrophils, which bind and neutralizes pathogens.


abducens nerve maturation

A developmental process, independent of morphogenetic (shape) change, that is required for the abducens nerve to attain its fully functional state. The motor function of the abducens nerve is to contract the lateral rectus which results in abduction of the eye.


histamine catabolic process

The chemical reactions and pathways resulting in the breakdown of histamine, a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans.


follicular fluid formation in ovarian follicle antrum involved in distinct antral spaces stage

The menstrual cycle process in which one central cavity separating the oocyte/cumulus complex from mural granulosa and theca cells is formed as part of the antral spaces stage of oogenesis.


somatic sex determination

The determination of sex and sexual phenotypes in an organism's soma.


regulation of intracellular mRNA localization

Any process that modulates the frequency, rate or extent of intracellular mRNA localization.


commitment of multipotent stem cells to neuronal lineage in forebrain

The initial commitment of cells whereby the developmental fate of a cell becomes restricted such that it will develop into some type of neuron in the forebrain.


connective tissue replacement

The series of events leading to growth of connective tissue when loss of tissues that are incapable of regeneration occurs, or when fibrinous exudate cannot be adequately cleared.


hair follicle morphogenesis

The process in which the anatomical structures of the hair follicle are generated and organized.


negative regulation of the force of heart contraction by acetylcholine

The process in which acetylcholine released from vagus nerve endings binds to muscarinic receptors and decreases the force of heart muscle contraction.


protein localization to cell periphery

A process in which a protein is transported to, or maintained in, the cell periphery.


wobble position ribose methylation

The process in which the ribose base of the nucleotide at position 34 in the anticodon of a tRNA is post-transcriptionally methylated at the 2'O position.


positive regulation of sodium ion transport

Any process that increases the frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


Catalysis of the reaction: adenylyl-[L-glutamate:ammonia ligase (ADP-forming)] + H2O = AMP + [L-glutamate:ammonia ligase (ADP-forming)].