host cell peroxisome

A small host cell organelle enclosed by a single membrane, and found in most eukaryotic cells. Contains peroxidases and other enzymes involved in a variety of metabolic processes including free radical detoxification, lipid catabolism and biosynthesis, and hydrogen peroxide metabolism.


UL38_HCMVA Apoptosis inhibitor UL38 (sprot)


suppression by virus of host natural killer cell activation

biolink:BiologicalProcess biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:Occurrent biolink:OntologyClass biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of natural killer cell activation in the host.


UL43_HCMVA Tegument protein UL43 (sprot)


RIR1_HCMVA Ribonucleoside-diphosphate reductase large subunit-like protein (sprot)


TRX1_HCMVA Triplex capsid protein 1 (sprot)


ITP_HCMVA Inner tegument protein (sprot)


LTP_HCMVA Large tegument protein deneddylase (sprot)


UL49_HCMVA Uncharacterized protein UL49 (sprot)


UL97_HCMVA Serine/threonine protein kinase UL97 (sprot)


VPAP_HCMVA DNA polymerase processivity factor (sprot)


NEC2_HCMVA Nuclear egress protein 2 (sprot)


TRM2_HCMVA Tripartite terminase subunit 2 (sprot)


UL52_HCMVA Packaging protein UL32 homolog (sprot)


NEC1_HCMVA Nuclear egress protein 1 (sprot)


GN_HCMVA Envelope glycoprotein N (sprot)


CVC1_HCMVA Capsid vertex component 1 (sprot)


CEP2_HCMVA Cytoplasmic envelopment protein 2 (sprot)


IR11_HCMVA Viral Fc-gamma receptor-like protein IR11 (sprot)


UL34_HCMVA Transcriptional regulator UL34 (sprot)


TEG7_HCMVA Tegument protein UL51 homolog (sprot)


DUT_HCMVA Deoxyuridine 5'-triphosphate nucleotidohydrolase (sprot)


HEPA_HCMVA DNA helicase/primase complex-associated protein (sprot)


GL_HCMVA Envelope glycoprotein L (sprot)


UL116_HCMVA Uncharacterized protein UL116 (sprot)


UL128_HCMVA Uncharacterized protein UL128 (sprot)


UL10_HCMVA Uncharacterized protein UL10 (sprot)


UL15A_HCMVA Uncharacterized protein UL15A (sprot)


UL23_HCMVA Tegument protein UL23 (sprot)


suppression of host innate immune response

Any process in which a symbiont stops, prevents, or reduces the frequency, rate or extent of the innate immune response of the host organism, the host's first line of defense against infection. The host is defined as the larger of the organisms involved in a symbiotic interaction.


UL33_HCMVA G-protein coupled receptor homolog UL33 (sprot)


UL04_HCMVA Early glycoprotein GP48 (sprot)


DNBI_HCMVA Major DNA-binding protein (sprot)


IL10H_HCMVA Viral interleukin-10 homolog (sprot)


EP84_HCMVA Early phosphoprotein p84 (sprot)


VIE2_HCMVA Viral transcription factor IE2 (sprot)


US18_HCMVA Transmembrane protein US18 (sprot)


US19_HCMVA Transmembrane protein HWLF4 (sprot)


UL132_HCMVA Envelope glycoprotein UL132 (sprot)


US34A_HCMVA Uncharacterized protein US34A (sprot)


SCP_HCMVA Small capsomere-interacting protein (sprot)


UL21A_HCMVA Uncharacterized protein UL21A (sprot)


A0A1P7U1I1_HCMVM Membrane glycoprotein UL8 (trembl)


UL74A_HCMVM Uncharacterized protein UL74A (sprot)


UL148_HCMVM Membrane protein UL148 (sprot)


U147A_HCMVM Uncharacterized protein UL147A (sprot)


US24_HCMVM Tegument protein US24 (sprot)


US13_HCMVM Membrane protein US13 (sprot)


VP22_HCMVM Tegument protein UL24 (sprot)


UL09_HCMVM Membrane glycoprotein UL9 (sprot)


UL20_HCMVM Membrane protein UL20 (sprot)


UL147_HCMVM Putative viral CXC chemokine 2 (sprot)


CEP1_HCMVM Cytoplasmic envelopment protein 1 (sprot)


TRX1_HCMVM Triplex capsid protein 1 (sprot)


CEP2_HCMVM Cytoplasmic envelopment protein 2 (sprot)


UL15A_HCMVM Uncharacterized protein UL15A (sprot)


UL144_HCMVM Membrane glycoprotein UL144 (sprot)


US19_HCMVM Transmembrane protein US19 (sprot)


VICA_HCMVM Viral inhibitor of caspase-8-induced apoptosis (sprot)


US30_HCMVM Uncharacterized protein US30 (sprot)


US08_HCMVM Membrane glycoprotein US8 (sprot)


GB_HCMVM Envelope glycoprotein B (sprot)


UL119_HCMVM Viral Fc-gamma receptor-like protein UL119 (sprot)


UL34_HCMVM Transcriptional regulator UL34 (sprot)


US09_HCMVM Membrane glycoprotein US9 (sprot)


IL10H_HCMVM Viral interleukin-10 homolog (sprot)


TRM1_HCMVM Tripartite terminase subunit 1 (sprot)


VPAP_HCMVM DNA polymerase processivity factor (sprot)


GL_HCMVM Envelope glycoprotein L (sprot)


VIE1_HCMVM Immediate early protein IE1 (sprot)


UL130_HCMVM Envelope glycoprotein UL130 (sprot)


TRM3_HCMVM Tripartite terminase subunit 3 (sprot)


UL121_HCMVM Membrane protein UL121 (sprot)


US14_HCMVM Membrane protein US14 (sprot)


US22_HCMVM Tegument protein US22 (sprot)


US07_HCMVM Membrane glycoprotein US7 (sprot)


US27_HCMVM Envelope glycoprotein US27 (sprot)


UL23_HCMVM Tegument protein UL23 (sprot)


DNBI_HCMVM Major DNA-binding protein (sprot)


US02_HCMVM Unique short US2 glycoprotein (sprot)


UL35_HCMVM Tegument protein UL35 (sprot)


US12_HCMVM Uncharacterized protein US12 (sprot)


US18_HCMVM Transmembrane protein US18 (sprot)


TEG7_HCMVM Tegument protein UL51 homolog (sprot)


SCP_HCMVM Small capsomere-interacting protein (sprot)


HELI_HCMVM DNA replication helicase (sprot)


US03_HCMVM Membrane glycoprotein US3 (sprot)


DNA endonuclease activity

biolink:MolecularActivity biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:Occurrent biolink:OntologyClass biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acid by creating internal breaks.


US28_HCMVM Envelope protein US28 (sprot)


UL18_HCMVM Membrane glycoprotein UL18 (sprot)


US15_HCMVM Membrane protein US15 (sprot)


US10_HCMVM Membrane glycoprotein US10 (sprot)


NEC1_HCMVM Nuclear egress protein 1 (sprot)


US29_HCMVM Uncharacterized protein US29 (sprot)


UL38_HCMVM Apoptosis inhibitor UL38 (sprot)


UL26_HCMVM Tegument protein UL26 (sprot)


US20_HCMVM Membrane protein US20 (sprot)


TRM2_HCMVM Tripartite terminase subunit 2 (sprot)


GO_HCMVM Envelope glycoprotein O (sprot)


negative regulation of viral entry into host cell

Any process that stops, prevents, or reduces the frequency, rate or extent of the entry of viral entry into a host cell.


positive regulation of receptor signaling pathway via JAK-STAT

Any process that activates or increases the frequency, rate or extent of the JAK-STAT signaling pathway activity.


UL132_HCMVM Envelope glycoprotein UL132 (sprot)


UL21A_HCMVM Uncharacterized protein UL21A (sprot)


UL142_HCMVM Membrane glycoprotein UL142 (sprot)


GN_HCMVM Envelope glycoprotein N (sprot)


UL124_HCMVM Uncharacterized protein UL124 (sprot)


US21_HCMVM Membrane protein US21 (sprot)


UNG_HCMVM Uracil-DNA glycosylase (sprot)


CEP3_HCMVM Cytoplasmic envelopment protein 3 (sprot)


HEPA_HCMVM DNA helicase/primase complex-associated protein (sprot)


TRX2_HCMVM Triplex capsid protein 2 (sprot)


US34A_HCMVM Uncharacterized protein US34A (sprot)


US11_HCMVM Membrane glycoprotein US11 (sprot)


US06_HCMVM Unique short US6 glycoprotein (sprot)


UL139_HCMVM Membrane glycoprotein UL139 (sprot)


VIE2_HCMVM Viral transcription factor IE2 (sprot)


UL120_HCMVM Membrane protein UL120 (sprot)


EP84_HCMVM Early phosphoprotein p84 (sprot)


GM_HCMVM Envelope glycoprotein M (sprot)


UL97_HCMVM Serine/threonine protein kinase UL97 (sprot)


CVC1_HCMVM Capsid vertex component 1 (sprot)


UL87_HCMVM Uncharacterized protein UL87 (sprot)


PP65_HCMVM 65 kDa phosphoprotein (sprot)


SCAF_HCMVM Capsid scaffolding protein (sprot)


CVC2_HCMVM Capsid vertex component 2 (sprot)


GH_HCMVM Envelope glycoprotein H (sprot)


DUT_HCMVM Deoxyuridine 5'-triphosphate nucleotidohydrolase (sprot)


ICP27_HCMVM mRNA export factor ICP27 homolog (sprot)


DPOL_HCMVM DNA polymerase catalytic subunit (sprot)


UL52_HCMVM Packaging protein UL32 homolog (sprot)


NEC2_HCMVM Nuclear egress protein 2 (sprot)


LTP_HCMVM Large tegument protein deneddylase (sprot)


ITP_HCMVM Inner tegument protein (sprot)


RIR1_HCMVM Ribonucleoside-diphosphate reductase large subunit-like protein (sprot)


UL43_HCMVM Tegument protein UL43 (sprot)


VGLI_HCMVM UL37 immediate early glycoprotein (sprot)


UL33_HCMVM G-protein coupled receptor homolog UL33 (sprot)


PP150_HCMVM Tegument protein pp150 (sprot)


UL14_HCMVM Uncharacterized protein UL14 (sprot)


UL13_HCMVM Uncharacterized protein UL13 (sprot)


UL10_HCMVM Uncharacterized protein UL10 (sprot)


UL07_HCMVM CEACAM1-like protein UL7 (sprot)


UL06_HCMVM Uncharacterized protein UL6 (sprot)


UL04_HCMVM Envelope glycoprotein UL4 (sprot)


UL02_HCMVM Uncharacterized protein UL2 (sprot)


RL13_HCMVM Membrane protein RL13 (sprot)


RL12_HCMVM Uncharacterized protein RL12 (sprot)


RL11_HCMVM Membrane glycoprotein RL11 (sprot)


Q7ZGS3_9RETR Gag-Pol polyprotein (trembl)


Q7ZGS4_9RETR Retroviral gag protein (trembl)


A0A220IGC1_9CIRC Replication-associated protein (trembl)


A0A220IGC7_9CIRC Capsid protein (trembl)


A0A220IGD8_9CIRC Replication-associated protein (trembl)


A0A220IGD4_9CIRC Replication-associated protein (trembl)


A0A142J7H8_9VIRU Replication associated protein (trembl)


A0A125R3J8_9VIRU Replication associated protein (trembl)


A0A0E3DBE3_9VIRU Replication-associated protein (trembl)


A0A4D6K2L4_9VIRU Replication-associated protein (trembl)


GN_HHV11 Envelope glycoprotein N (sprot)

A protein that is a translation product of the gN gene in Herpes simplex virus type 1 strain 17.


GM_HHV11 Envelope glycoprotein M (sprot)

A protein that is a translation product of the gM gene in Herpes simplex virus type 1 strain 17.


CEP3_HHV11 Cytoplasmic envelopment protein 3 (sprot)


UL13_HHV11 Serine/threonine-protein kinase UL13 (sprot)


TEG3_HHV11 Tegument protein UL14 (sprot)


DPOL_HHV11 DNA polymerase catalytic subunit (sprot)

A protein that is a translation product of the UL30 gene in Herpes simplex virus type 1 strain 17.


DNA polymerase complex

biolink:CellularComponent biolink:AnatomicalEntity biolink:OrganismalEntity biolink:BiologicalEntity biolink:NamedThing biolink:PhysicalEssence biolink:SubjectOfInvestigation biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

A protein complex that possesses DNA polymerase activity and is involved in template directed synthesis of DNA.


TRM3_HHV11 Tripartite terminase subunit 3 (sprot)


DNBI_HHV11 Major DNA-binding protein (sprot)


US03_HHV11 Serine/threonine-protein kinase US3 (sprot)


suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway

Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of the host viral-induced cytoplasmic pattern recognition receptor signaling pathway. This is a mechanism by which the virus evades the host innate immune response.


negative regulation of protein import into nucleus

Any process that stops, prevents, or reduces the frequency, rate or extent of the movement of proteins from the cytoplasm into the nucleus.


suppression of host T-cell mediated immune response

Any process in which a symbiont stops, prevents, or reduces the frequency, rate or extent of the T-cell mediated immune response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.


negative regulation of protein localization to nucleus

Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to nucleus.


ICP22_HHV11 Transcriptional regulator ICP22 (sprot)


GE_HHV11 Envelope glycoprotein E (sprot)

A protein that is a translation product of the gE gene in Herpes simplex virus type 1 strain 17.


GH_HHV11 Envelope glycoprotein H (sprot)

A protein that is a translation product of the gH gene in Herpes simplex virus type 1 strain 17.


GJ_HHV11 Envelope glycoprotein J (sprot)

A protein that is a translation product of the gJ gene in Herpes simplex virus type 1 strain 17.


GG_HHV11 Envelope glycoprotein G (sprot)

A protein that is a translation product of the gG gene in Herpes simplex virus type 1 strain 17.


GI_HHV11 Envelope glycoprotein I (sprot)

A protein that is a translation product of the gI gene in Herpes simplex virus type 1 strain 17.


VP16_HHV11 Tegument protein VP16 (sprot)

A protein that is a translation product of the UL48 gene in Herpes simplex virus type 1 strain 17.


core promoter sequence-specific DNA binding

Binding to a sequence of DNA that is part of a core promoter region. The core promoter is composed of the transcription start site and binding sites for the RNA polymerase and the basal transcription machinery. The transcribed region might be described as a gene, cistron, or operon.


DNA-binding transcription factor binding

Binding to a DNA-binding transcription factor, a protein that interacts with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription.


molecular function activator activity

A molecular function regulator that activates or increases the activity of its target via non-covalent binding that does not result in covalent modification to the target.


protein-containing complex assembly

The aggregation, arrangement and bonding together of a set of macromolecules to form a protein-containing complex.


replication compartment

Globular nuclear domains where the transcription and replication of the viral genome occurs. More than one site can be present simultaneously.


ICP4_HHV11 Major viral transcription factor ICP4 (sprot)


response to type I interferon

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a type I interferon stimulus. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.


ICP0_HHV11 E3 ubiquitin-protein ligase ICP0 (sprot)


positive regulation of protein catabolic process

Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds.


RIR1_HHV11 Ribonucleoside-diphosphate reductase large subunit (sprot)


GL_HHV11 Envelope glycoprotein L (sprot)

A protein that is a translation product of the gL gene in Herpes simplex virus type 1 strain 17.


UNG_HHV11 Uracil-DNA glycosylase (sprot)


NP03_HHV11 Nuclear phosphoprotein UL3 (sprot)


HELI_HHV11 DNA replication helicase (sprot)


CEP1_HHV11 Cytoplasmic envelopment protein 1 (sprot)


HEPA_HHV11 DNA helicase/primase complex-associated protein (sprot)


OBP_HHV11 Replication origin-binding protein (sprot)


CEP2_HHV11 Cytoplasmic envelopment protein 2 (sprot)


CVC1_HHV11 Capsid vertex component 1 (sprot)


TRX2_HHV11 Triplex capsid protein 2 (sprot)


TEG4_HHV11 Tegument protein UL21 (sprot)


CVC2_HHV11 Capsid vertex component 2 (sprot)


SCAF_HHV11 Capsid scaffolding protein (sprot)


GB_HHV11 Envelope glycoprotein B (sprot)

A protein that is a translation product of the gB gene in Herpes simplex virus type 1 strain 17.


TRM1_HHV11 Tripartite terminase subunit 1 (sprot)


NEC1_HHV11 Nuclear egress protein 1 (sprot)


UL32_HHV11 Packaging protein UL32 (sprot)


TRM2_HHV11 Tripartite terminase subunit 2 (sprot)


NEC2_HHV11 Nuclear egress protein 2 (sprot)


SCP_HHV11 Small capsomere-interacting protein (sprot)


LTP_HHV11 Large tegument protein deneddylase (sprot)


deubiquitinase activity

An isopeptidase activity that cleaves ubiquitin from a target protein to which it is conjugated.


ITP_HHV11 Inner tegument protein (sprot)


protein-glutamine glutaminase activity

Catalysis of the reaction: protein L-glutamine + H2O = protein L-glutamate + NH3.


RIR2_HHV11 Ribonucleoside-diphosphate reductase small subunit (sprot)


SHUT_HHV11 Virion host shutoff protein (sprot)


PAP_HHV11 DNA polymerase processivity factor (sprot)


MB43_HHV11 Membrane protein UL43 (sprot)


GC_HHV11 Envelope glycoprotein C (sprot)


EV45_HHV11 Envelope protein UL45 (sprot)


TEG1_HHV11 Tegument protein UL46 (sprot)


TEG5_HHV11 Tegument protein UL47 (sprot)


VP22_HHV11 Tegument protein VP22 (sprot)


DUT_HHV11 Deoxyuridine 5'-triphosphate nucleotidohydrolase (sprot)


TEG7_HHV11 Tegument protein UL51 (sprot)


suppression by virus of host mRNA processing

Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of mRNA processing in the host cell. mRNA processing is the conversion of a primary mRNA transcript into one or more mature mRNA(s) prior to translation into polypeptide.


TEG6_HHV11 Tegument protein UL55 (sprot)


TRX1_HHV11 Triplex capsid protein 1 (sprot)


ICP34_HHV11 Neurovirulence factor ICP34.5 (sprot)


GK_HHV11 Envelope glycoprotein K (sprot)

A protein that is a translation product of the gK gene in Herpes simplex virus type 1 strain 17.


GD_HHV11 Envelope glycoprotein D (sprot)

A protein that is a translation product of the gD gene in Herpes simplex virus type 1 strain 17.


GB_HHV2H Envelope glycoprotein B (sprot)


US03_HHV2H Serine/threonine-protein kinase US3 (sprot)


GG_HHV2H Envelope glycoprotein G (sprot)


GI_HHV2H Envelope glycoprotein I (sprot)


GJ_HHV2H Envelope glycoprotein J (sprot)


CEP3_HHV2H Cytoplasmic envelopment protein 3 (sprot)


GK_HHV2H Envelope glycoprotein K (sprot)


UNG_HHV2H Uracil-DNA glycosylase (sprot)


exit from host cell

The movement of an organism out of a cell of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.


HELI_HHV2H DNA replication helicase (sprot)


GL_HHV2H Envelope glycoprotein L (sprot)


NP03_HHV2H Nuclear phosphoprotein UL3 (sprot)


TEG6_HHV2H Tegument protein UL55 (sprot)


ICP34_HHV2H Neurovirulence factor ICP34.5 (sprot)


ICP0_HHV2H E3 ubiquitin-protein ligase ICP0 (sprot)


VP16_HHV2H Tegument protein VP16 (sprot)


SHUT_HHV2H Virion host shutoff protein (sprot)


RIR2_HHV2H Ribonucleoside-diphosphate reductase small subunit (sprot)


CEP1_HHV2H Cytoplasmic envelopment protein 1 (sprot)


HEPA_HHV2H DNA helicase/primase complex-associated protein (sprot)


OBP_HHV2H Replication origin-binding protein (sprot)


GM_HHV2H Envelope glycoprotein M (sprot)


UL13_HHV2H Serine/threonine-protein kinase UL13 (sprot)


TEG3_HHV2H Tegument protein UL14 (sprot)


TRM3_HHV2H Tripartite terminase subunit 3 (sprot)


CEP2_HHV2H Cytoplasmic envelopment protein 2 (sprot)


CVC1_HHV2H Capsid vertex component 1 (sprot)


TRX2_HHV2H Triplex capsid protein 2 (sprot)


TEG4_HHV2H Tegument protein UL21 (sprot)


GH_HHV2H Envelope glycoprotein H (sprot)


CVC2_HHV2H Capsid vertex component 2 (sprot)


SCAF_HHV2H Capsid scaffolding protein (sprot)


TRM1_HHV2H Tripartite terminase subunit 1 (sprot)


DNBI_HHV2H Major DNA-binding protein (sprot)


DPOL_HHV2H DNA polymerase catalytic subunit (sprot)


NEC1_HHV2H Nuclear egress protein 1 (sprot)


UL32_HHV2H Packaging protein UL32 (sprot)


TRM2_HHV2H Tripartite terminase subunit 2 (sprot)


NEC2_HHV2H Nuclear egress protein 2 (sprot)


SCP_HHV2H Small capsomere-interacting protein (sprot)


LTP_HHV2H Large tegument protein deneddylase (sprot)


ITP_HHV2H Inner tegument protein (sprot)


TRX1_HHV2H Triplex capsid protein 1 (sprot)


RIR1_HHV2H Ribonucleoside-diphosphate reductase large subunit (sprot)


negative regulation of tumor necrosis factor-mediated signaling pathway

Any process that decreases the rate or extent of the tumor necrosis factor-mediated signaling pathway. The tumor necrosis factor-mediated signaling pathway is the series of molecular signals generated as a consequence of tumor necrosis factor binding to a cell surface receptor.


PAP_HHV2H DNA polymerase processivity factor (sprot)


MB43_HHV2H Membrane protein UL43 (sprot)


EV45_HHV2H Envelope protein UL45 (sprot)


TEG1_HHV2H Tegument protein UL46 (sprot)


TEG5_HHV2H Tegument protein UL47 (sprot)


VP22_HHV2H Tegument protein VP22 (sprot)


DUT_HHV2H Deoxyuridine 5'-triphosphate nucleotidohydrolase (sprot)


TEG7_HHV2H Tegument protein UL51 (sprot)


ICP22_HHV2H E3 ubiquitin ligase ICP22 (sprot)


GE_HHV2H Envelope glycoprotein E (sprot)


RNB_HHV2H Probable RNA-binding protein (sprot)


ICP4_HHV2H Major viral transcription factor ICP4 homolog (sprot)


GD_HHV2H Envelope glycoprotein D (sprot)


GN_HHV2H Envelope glycoprotein N (sprot)


GC_HHV2H Envelope glycoprotein C (sprot)


A0A2N9DYY6_HHV6U Tripartite terminase subunit 3 (trembl)


SCAF_HHV6U Capsid scaffolding protein (sprot)


TRX2_HHV6U Triplex capsid protein 2 (sprot)


CVC1_HHV6U Capsid vertex component 1 (sprot)


CEP2_HHV6U Cytoplasmic envelopment protein 2 (sprot)


GCVK_HHV6U Probable ganciclovir kinase (sprot)


CEP3_HHV6U Cytoplasmic envelopment protein 3 (sprot)


DPOL_HHV6U DNA polymerase catalytic subunit (sprot)


GB_HHV6U Envelope glycoprotein B (sprot)


NEC1_HHV6U Nuclear egress protein 1 (sprot)


DNBI_HHV6U Major DNA-binding protein (sprot)


LTP_HHV6U Large tegument protein deneddylase (sprot)


RIR1_HHV6U Ribonucleoside-diphosphate reductase large subunit-like protein (sprot)


UNG_HHV6U Uracil-DNA glycosylase (sprot)


TRX1_HHV6U Triplex capsid protein 1 (sprot)


ICP27_HHV6U mRNA export factor ICP27 homolog (sprot)


HELI_HHV6U DNA replication helicase (sprot)


HEPA_HHV6U DNA helicase/primase complex-associated protein (sprot)


OBP_HHV6U Replication origin-binding protein (sprot)


UL33_HHV6U G-protein coupled receptor homolog U12 (sprot)


VU51_HHV6U G-protein coupled receptor homolog U51 (sprot)


TRM1_HHV6U Tripartite terminase subunit 1 (sprot)


CVC2_HHV6U Capsid vertex component 2 (sprot)


ITP_HHV6U Inner tegument protein (sprot)


VPAP_HHV6U DNA polymerase processivity factor (sprot)


CEP1_HHV6U Cytoplasmic envelopment protein 1 (sprot)


CCU83_HHV6U Putative CC-type chemokine U83 (sprot)


UL32_HHV6U Packaging protein UL32 (sprot)


NEC2_HHV6U Nuclear egress protein 2 (sprot)


TEG7_HHV6U Tegument protein UL51 homolog (sprot)


GL_HHV6U Envelope glycoprotein L (sprot)


GH_HHV6U Envelope glycoprotein H (sprot)


P100_HHV6U Large structural phosphoprotein (sprot)


GM_HHV6U Envelope glycoprotein M (sprot)


GN_HHV6U Envelope glycoprotein N (sprot)


DUT_HHV6U Deoxyuridine 5'-triphosphate nucleotidohydrolase (sprot)


U15_HHV6U Uncharacterized protein U15 (sprot)


U18_HHV6U Putative immediate early glycoprotein (sprot)


UL38_HHV6U Apoptosis inhibitor U19 (sprot)


SCP_HHV6U Small capsomere-interacting protein (sprot)


TRM2_HHV6U Tripartite terminase subunit 2 (sprot)


U91_HHV6U Uncharacterized protein U91 (sprot)


IE2_HHV6U Immediate-early protein 2 (sprot)


OX2V_HHV6U Putative OX-2 membrane glycoprotein homolog (sprot)


GB_HHV6Z Envelope glycoprotein B (sprot)


GCVK_HHV6Z Probable ganciclovir kinase (sprot)


UNG_HHV6Z Uracil-DNA glycosylase (sprot)


GM_HHV6Z Envelope glycoprotein M (sprot)


HELI_HHV6Z DNA replication helicase (sprot)


HEPA_HHV6Z DNA helicase/primase complex-associated protein (sprot)


OBP_HHV6Z Replication origin-binding protein (sprot)


CEP1_HHV6Z Cytoplasmic envelopment protein 1 (sprot)


CEP3_HHV6Z Cytoplasmic envelopment protein 3 (sprot)


CCU83_HHV6Z Putative CC-type chemokine U83 (sprot)


GL_HHV6Z Envelope glycoprotein L (sprot)


CVC2_HHV6Z Capsid vertex component 2 (sprot)


DNBI_HHV6Z Major DNA-binding protein (sprot)


ICP27_HHV6Z mRNA export factor ICP27 homolog (sprot)


DUT_HHV6Z Deoxyuridine 5'-triphosphate nucleotidohydrolase (sprot)


VU51_HHV6Z G-protein coupled receptor homolog U51 (sprot)


GH_HHV6Z Envelope glycoprotein H (sprot)


TRM1_HHV6Z Tripartite terminase subunit 1 (sprot)


TEG7_HHV6Z Tegument protein UL51 homolog (sprot)


GN_HHV6Z Envelope glycoprotein N (sprot)


P100_HHV6Z Large structural phosphoprotein (sprot)


IE2_HHV6Z Immediate-early protein 2 (sprot)


OX2V_HHV6Z Putative OX-2 membrane glycoprotein homolog (sprot)


CEP2_HHV6Z Cytoplasmic envelopment protein 2 (sprot)


CVC1_HHV6Z Capsid vertex component 1 (sprot)


TRM3_HHV6Z Tripartite terminase subunit 3 (sprot)


TRX2_HHV6Z Triplex capsid protein 2 (sprot)


SCAF_HHV6Z Capsid scaffolding protein (sprot)


DPOL_HHV6Z DNA polymerase catalytic subunit (sprot)


UL32_HHV6Z Packaging protein UL32 homolog (sprot)


TRM2_HHV6Z Tripartite terminase subunit 2 (sprot)


NEC2_HHV6Z Nuclear egress protein 2 (sprot)


LTP_HHV6Z Large tegument protein deneddylase (sprot)


ITP_HHV6Z Inner tegument protein (sprot)


RIR1_HHV6Z Ribonucleoside-diphosphate reductase large subunit-like protein (sprot)


VPAP_HHV6Z DNA polymerase processivity factor (sprot)


U24A_HHV6Z Uncharacterized protein U24A (sprot)


VGCR_HHV6Z G-protein coupled receptor (sprot)


G protein-coupled peptide receptor activity

Combining with a peptide and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.


NEC1_HHV6Z Nuclear egress protein 1 (sprot)


SCP_HHV6Z Small capsomere-interacting protein (sprot)


TRX1_HHV6Z Triplex capsid protein 1 (sprot)


UL38_HHV6Z Apoptosis inhibitor U19 (sprot)


U18_HHV6Z Putative immediate early glycoprotein (sprot)


UNG_HHV7J Uracil-DNA glycosylase (sprot)


RIR1_HHV7J Ribonucleoside-diphosphate reductase large subunit-like protein (sprot)


DNBI_HHV7J Major DNA-binding protein (sprot)


DUT_HHV7J Deoxyuridine 5'-triphosphate nucleotidohydrolase (sprot)


DPOL_HHV7J DNA polymerase catalytic subunit (sprot)


GCVK_HHV7J Probable ganciclovir kinase (sprot)


TRX1_HHV7J Triplex capsid protein 1 (sprot)


SCAF_HHV7J Capsid scaffolding protein (sprot)


GB_HHV7J Envelope glycoprotein B (sprot)


GH_HHV7J Envelope glycoprotein H (sprot)


ICP27_HHV7J mRNA export factor ICP27 homolog (sprot)


HELI_HHV7J DNA replication helicase (sprot)


CEP3_HHV7J Cytoplasmic envelopment protein 3 (sprot)


CEP2_HHV7J Cytoplasmic envelopment protein 2 (sprot)


CVC1_HHV7J Capsid vertex component 1 (sprot)


NEC1_HHV7J Nuclear egress protein 1 (sprot)


LTP_HHV7J Large tegument protein deneddylase (sprot)


GN_HHV7J Envelope glycoprotein N (sprot)


GM_HHV7J Envelope glycoprotein M (sprot)


HEPA_HHV7J DNA helicase/primase complex-associated protein (sprot)


OBP_HHV7J Replication origin-binding protein (sprot)


UL33_HHV7J G-protein coupled receptor homolog U12 (sprot)


chemokine (C-C motif) ligand 19 binding

Binding to chemokine (C-C motif) ligand 19.


chemokine (C-C motif) ligand 21 binding

Binding to chemokine (C-C motif) ligand 21.


C-C motif chemokine 19 receptor activity

Combining with the C-C motif chemokine 19 (CCL19) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


VU51_HHV7J G-protein coupled receptor homolog U51 (sprot)


TRM1_HHV7J Tripartite terminase subunit 1 (sprot)


CVC2_HHV7J Capsid vertex component 2 (sprot)


ITP_HHV7J Inner tegument protein (sprot)


VPAP_HHV7J DNA polymerase processivity factor (sprot)


CEP1_HHV7J Cytoplasmic envelopment protein 1 (sprot)


TRM3_HHV7J Tripartite terminase subunit 3 (sprot)


UL32_HHV7J Packaging protein UL32 (sprot)


NEC2_HHV7J Nuclear egress protein 2 (sprot)


TEG7_HHV7J Tegument protein UL51 homolog (sprot)


GL_HHV7J Envelope glycoprotein L (sprot)


P100_HHV7J Large structural phosphoprotein (sprot)


GO_HHV7J Glycoprotein U47 homolog (sprot)


TRX2_HHV7J Triplex capsid protein 2 (sprot)


Q69507_HHV7J Small capsomere-interacting protein (trembl)


Q69508_HHV7J Tripartite terminase subunit 2 (trembl)


TRX1_HHV8P Triplex capsid protein 1 (sprot)


NEC1_HHV8P Nuclear egress protein 1 (sprot)


TRM2_HHV8P Tripartite terminase subunit 2 (sprot)


TEG7_HHV8P Tegument protein ORF55 (sprot)


NEC2_HHV8P Nuclear egress protein 2 (sprot)


CEP1_HHV8P Cytoplasmic envelopment protein 1 (sprot)


GH_HHV8P Envelope glycoprotein H (sprot)


RIR2_HHV8P Ribonucleoside-diphosphate reductase small subunit (sprot)


CVC1_HHV8P Capsid vertex component 1 (sprot)


GB_HHV8P Envelope glycoprotein B (sprot)


ORF50_HHV8P Putative transcription activator ORF50 (sprot)


GL_HHV8P Envelope glycoprotein L (sprot)


GM_HHV8P Envelope glycoprotein M (sprot)


perturbation of host innate immune response

A process in which an organism effects a change that affects the innate immune response of the host organism; the innate immune response is the host's first line of defense against infection. The host is defined as the larger of the organisms involved in a symbiotic interaction.


CEP2_HHV8P Cytoplasmic envelopment protein 2 (sprot)


ITP_HHV8P Inner tegument protein (sprot)


UL32_HHV8P Packaging protein UL32 homolog (sprot)


UNG_HHV8P Uracil-DNA glycosylase (sprot)


GN_HHV8P Envelope glycoprotein N (sprot)


TRM3_HHV8P Tripartite terminase subunit 3 (sprot)


ARBH_HHV8P Apoptosis regulator Bcl-2 homolog (sprot)


TRX2_HHV8P Triplex capsid protein 2 (sprot)


CEP3_HHV8P Cytoplasmic envelopment protein 3 (sprot)


VIRF3_HHV8P Viral IRF3-like protein (sprot)


PAP_HHV8P DNA polymerase processivity factor (sprot)


OX2V_HHV8P OX-2 membrane glycoprotein homolog (sprot)


MIR2_HHV8P E3 ubiquitin-protein ligase MIR2 (sprot)


positive regulation by symbiont of host receptor-mediated endocytosis

Any process in which a symbiont organism activates or increases the frequency, rate or extent of receptor mediated endocytosis, the uptake of external materials by cells, utilizing receptors to ensure specificity of transport, in its host organism.


suppression by virus of host interferon-mediated signaling pathway

Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of interferon-mediated signaling in the host organism.


MIR1_HHV8P E3 ubiquitin-protein ligase MIR1 (sprot)


SCP_HHV8P Small capsomere-interacting protein (sprot)


LTP_HHV8P Large tegument protein deneddylase (sprot)


RIR1_HHV8P Ribonucleoside-diphosphate reductase large subunit (sprot)


VIRF2_HHV8P Viral IRF2-like protein (sprot)


VIRF4_HHV8P Viral IRF4-like protein (sprot)


ICP27_HHV8P mRNA export factor ICP27 homolog (sprot)


DUT_HHV8P Deoxyuridine 5'-triphosphate nucleotidohydrolase (sprot)


ORF52_HHV8P Tegument protein ORF52 (sprot)


KBZIP_HHV8P E3 SUMO-protein ligase K-bZIP (sprot)


ORF48_HHV8P Tegument protein ORF48 (sprot)


HELI_HHV8P DNA replication helicase (sprot)


HEPA_HHV8P DNA helicase/primase complex-associated protein (sprot)


AN_HHV8P Shutoff alkaline exonuclease (sprot)


CVC2_HHV8P Capsid vertex component 2 (sprot)


SCAF_HHV8P Capsid scaffolding protein (sprot)


DYR_HHV8P Putative Dihydrofolate reductase (sprot)


VIL6_HHV8P Viral interleukin-6 homolog (sprot)


interleukin-6 receptor binding

Binding to an interleukin-6 receptor.


interleukin-6 receptor complex

A hexameric protein complex consisting of two molecules each of interleukin-6, interleukin-6 receptor alpha chain, and gp-130.


DPOL_HHV8P DNA polymerase catalytic subunit (sprot)


TRM1_HHV8P Tripartite terminase subunit 1 (sprot)


DNBI_HHV8P Major DNA-binding protein (sprot)


ORF4_HHV8P Complement control protein (sprot)


VCYCL_HHV8P viral cyclin homolog (sprot)


VGPCR_HHV8P viral G-protein coupled receptor (sprot)


VMI2_HHV8P Viral macrophage inflammatory protein 2 (sprot)


CXCR chemokine receptor binding

Binding to a chemokine receptor in the CXCR family.


LANA1_HHV8P Protein LANA1 (sprot)

A protein that is a translation product of the ORF73 gene in Human herpesvirus 8 strain GK18.


K4ISV1_9PLVG Pol protein (Fragment) (trembl)


K4ISV4_9PLVG Virion infectivity factor (trembl)


K4IV63_9PLVG Envelope glycoprotein gp160 (trembl)


ENV_HV1MA Envelope glycoprotein gp160 (sprot)


POL_HV1MA Gag-Pol polyprotein (sprot)

A lentivirus-type gag-pol polyprotein that is encoded in the genome of Human immunodeficiency virus type 1 group M subtype A (isolate MAL).


GAG_HV1MA Gag polyprotein (sprot)

A lentivirus-type gag polyprotein that is encoded in the genome of Human immunodeficiency virus type 1 group M subtype A (isolate MAL).


VIF_HV1MA Virion infectivity factor (sprot)


regulatory region RNA binding

Binding to a RNA region that regulates a nucleic acid-based process. Such processes include transcription, DNA replication, and DNA repair.


GAG_HV1U4 Gag polyprotein (sprot)

A lentivirus-type gag polyprotein that is encoded in the genome of Human immunodeficiency virus type 1 group M subtype A (isolate U455).


VIF_HV1U4 Virion infectivity factor (sprot)


POL_HV1U4 Gag-Pol polyprotein (sprot)

A lentivirus-type gag-pol polyprotein that is encoded in the genome of Human immunodeficiency virus type 1 group M subtype A (isolate U455).


GAG_HV1A2 Gag polyprotein (sprot)

A lentivirus-type gag polyprotein that is encoded in the genome of Human immunodeficiency virus type 1 group M subtype B (isolate ARV2/SF2).


POL_HV1A2 Gag-Pol polyprotein (sprot)

A lentivirus-type gag-pol polyprotein that is encoded in the genome of Human immunodeficiency virus type 1 group M subtype B (isolate ARV2/SF2).


ENV_HV1A2 Envelope glycoprotein gp160 (sprot)

An HIV env gene translation product that is encoded in the genome of Human immunodeficiency virus type 1 group M subtype B (isolate ARV2/SF2).


VIF_HV1A2 Virion infectivity factor (sprot)


activation of transmembrane receptor protein tyrosine kinase activity

Any process that initiates the activity of the inactive transmembrane receptor protein tyrosine kinase activity.


GAG_HV1B1 Gag polyprotein (sprot)

A lentivirus-type gag polyprotein that is encoded in the genome of Human immunodeficiency virus type 1 group M subtype B (isolate BH10).


POL_HV1B1 Gag-Pol polyprotein (sprot)

A lentivirus-type gag-pol polyprotein that is encoded in the genome of Human immunodeficiency virus type 1 group M subtype B (isolate BH10).


ENV_HV1B1 Envelope glycoprotein gp160 (sprot)


protein-containing complex binding

Binding to a macromolecular complex.


host cell periphery

The part of a cell encompassing the cell cortex, the plasma membrane, and any external encapsulating structures of a host cell.


thioesterase binding

Binding to a thioesterase.


negative regulation of CD4 production

Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of CD4.


regulation of calcium-mediated signaling

Any process that modulates the frequency, rate or extent of calcium-mediated signaling, the process in which a cell uses calcium ions to convert an extracellular signal into a response.


protein export from nucleus

The directed movement of a protein from the nucleus into the cytoplasm.


VIF_HV1B1 Virion infectivity factor (sprot)


GAG_HV1BR Gag polyprotein (sprot)

A lentivirus-type gag polyprotein that is encoded in the genome of Human immunodeficiency virus type 1 group M subtype B (isolate BRU/LAI).


POL_HV1BR Gag-Pol polyprotein (sprot)

A lentivirus-type gag-pol polyprotein that is encoded in the genome of Human immunodeficiency virus type 1 group M subtype B (isolate BRU/LAI).


ENV_HV1BR Envelope glycoprotein gp160 (sprot)


peptidase activator activity

Binds to and increases the activity of a peptidase.


regulation of T cell activation

Any process that modulates the frequency, rate or extent of T cell activation.


positive regulation of NF-kappaB transcription factor activity

Any process that activates or increases the frequency, rate or extent of activity of the transcription factor NF-kappaB.


membrane hyperpolarization

The process in which membrane potential increases with respect to its steady-state potential, usually from negative potential to a more negative potential. For example, during the repolarization phase of an action potential the membrane potential often becomes more negative or hyperpolarized before returning to the steady-state resting potential.


positive regulation of protein localization to nucleus

Any process that activates or increases the frequency, rate or extent of protein localization to nucleus.


negative regulation of cellular respiration

Any process that stops, prevents or reduces the frequency, rate or extent of cellular respiration.


VIF_HV1BR Virion infectivity factor (sprot)


ENV_HV1H2 Envelope glycoprotein gp160 (sprot)

An HIV env gene translation product that is encoded in the genome of human immunodeficiency virus type 1 group M subtype B (isolate HXB2).


actin filament organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments. Includes processes that control the spatial distribution of actin filaments, such as organizing filaments into meshworks, bundles, or other structures, as by cross-linking.


evasion of host immune response

A process by which an organism avoids the effects of the host organism's immune response. The host is defined as the larger of the organisms involved in a symbiotic interaction.


POL_HV1H2 Gag-Pol polyprotein (sprot)

A lentivirus-type gag-pol polyprotein that is encoded in the genome of human immunodeficiency virus type 1 group M subtype B (isolate HXB2).


integrase activity

Catalysis of the integration of one DNA segment into another.


GAG_HV1H2 Gag polyprotein (sprot)

A lentivirus-type gag polyprotein that is encoded in the genome of human immunodeficiency virus type 1 group M subtype B (isolate HXB2).


host cellular component

Any cellular component of a host cell. The host is an organism in which another organism, for instance a parasite or symbiont, spends part or all of its life cycle and from which it obtains nourishment and/or protection.


REV_HV1H2 Protein Rev (sprot)

A protein that is a translation product of the rev gene in human immunodeficiency virus type 1 group M subtype B (isolate HXB2).


VIF_HV1H2 Virion infectivity factor (sprot)

A protein that is a translation product of the vif gene in human immunodeficiency virus type 1 group M subtype B (isolate HXB2).


negative regulation of DNA repair

Any process that stops, prevents, or reduces the frequency, rate or extent of DNA repair.


positive regulation by symbiont of host apoptotic process

Any process in which an organism activates, maintains or increases the frequency, rate or extent of programmed cell death in the host, where programmed cell death proceeds by apoptosis. The host is defined as the larger of the organisms involved in a symbiotic interaction.


ENV_HV1JR Envelope glycoprotein gp160 (sprot)

An HIV env gene translation product that is encoded in the genome of Human immunodeficiency virus type 1 group M subtype B (isolate JRCSF).


positive regulation of cell growth

Any process that activates or increases the frequency, rate, extent or direction of cell growth.


GAG_HV1JR Gag polyprotein (sprot)

A lentivirus-type gag polyprotein that is encoded in the genome of Human immunodeficiency virus type 1 group M subtype B (isolate JRCSF).


POL_HV1JR Gag-Pol polyprotein (sprot)

A lentivirus-type gag-pol polyprotein that is encoded in the genome of Human immunodeficiency virus type 1 group M subtype B (isolate JRCSF).


VIF_HV1JR Virion infectivity factor (sprot)


ENV_HV1MN Envelope glycoprotein gp160 (sprot)


GAG_HV1MN Gag polyprotein (sprot)

A lentivirus-type gag polyprotein that is encoded in the genome of Human immunodeficiency virus type 1 group M subtype B (isolate MN).


VIF_HV1MN Virion infectivity factor (sprot)


POL_HV1MN Gag-Pol polyprotein (sprot)

A lentivirus-type gag-pol polyprotein that is encoded in the genome of Human immunodeficiency virus type 1 group M subtype B (isolate MN).


ENV_HV1RH Envelope glycoprotein gp160 (sprot)


GAG_HV1RH Gag polyprotein (sprot)

A lentivirus-type gag polyprotein that is encoded in the genome of Human immunodeficiency virus type 1 group M subtype B (isolate RF/HAT3).


VIF_HV1RH Virion infectivity factor (sprot)


POL_HV1RH Gag-Pol polyprotein (sprot)

A lentivirus-type gag-pol polyprotein that is encoded in the genome of Human immunodeficiency virus type 1 group M subtype B (isolate RF/HAT3).


GAG_HV1B9 Gag polyprotein (sprot)

A lentivirus-type gag polyprotein that is encoded in the genome of Human immunodeficiency virus type 1 group M subtype B (strain 89.6).


POL_HV1B9 Gag-Pol polyprotein (sprot)

A lentivirus-type gag-pol polyprotein that is encoded in the genome of Human immunodeficiency virus type 1 group M subtype B (strain 89.6).


ENV_HV1B9 Envelope glycoprotein gp160 (sprot)


VIF_HV1B9 Virion infectivity factor (sprot)


GAG_HV192 Gag polyprotein (sprot)

A lentivirus-type gag polyprotein that is encoded in the genome of Human immunodeficiency virus type 1 group M subtype C (isolate 92BR025).


POL_HV192 Gag-Pol polyprotein (sprot)

A lentivirus-type gag-pol polyprotein that is encoded in the genome of Human immunodeficiency virus type 1 group M subtype C (isolate 92BR025).


VIF_HV192 Virion infectivity factor (sprot)


ENV_HV192 Envelope glycoprotein gp160 (sprot)


ENV_HV1EL Envelope glycoprotein gp160 (sprot)


POL_HV1EL Gag-Pol polyprotein (sprot)

A lentivirus-type gag-pol polyprotein that is encoded in the genome of Human immunodeficiency virus type 1 group M subtype D (isolate ELI).


GAG_HV1EL Gag polyprotein (sprot)

A lentivirus-type gag polyprotein that is encoded in the genome of Human immunodeficiency virus type 1 group M subtype D (isolate ELI).


VIF_HV1EL Virion infectivity factor (sprot)


VIF_HV193 Virion infectivity factor (sprot)


POL_HV193 Gag-Pol polyprotein (sprot)

A lentivirus-type gag-pol polyprotein that is encoded in the genome of Human immunodeficiency virus type 1 group M subtype F1 (isolate 93BR020).


GAG_HV193 Gag polyprotein (sprot)

A lentivirus-type gag polyprotein that is encoded in the genome of Human immunodeficiency virus type 1 group M subtype F1 (isolate 93BR020).


ENV_HV193 Envelope glycoprotein gp160 (sprot)


ENV_HV1VI Envelope glycoprotein gp160 (sprot)


VIF_HV1VI Virion infectivity factor (sprot)


POL_HV1VI Gag-Pol polyprotein (sprot)

A lentivirus-type gag-pol polyprotein that is encoded in the genome of Human immunodeficiency virus type 1 group M subtype F1 (isolate VI850).


GAG_HV1VI Gag polyprotein (sprot)

A lentivirus-type gag polyprotein that is encoded in the genome of Human immunodeficiency virus type 1 group M subtype F1 (isolate VI850).


VIF_HV190 Virion infectivity factor (sprot)


ENV_HV190 Envelope glycoprotein gp160 (sprot)


GAG_HV190 Gag polyprotein (sprot)

A lentivirus-type gag polyprotein that is encoded in the genome of Human immunodeficiency virus type 1 group M subtype H (isolate 90CF056).


POL_HV190 Gag-Pol polyprotein (sprot)

A lentivirus-type gag-pol polyprotein that is encoded in the genome of Human immunodeficiency virus type 1 group M subtype H (isolate 90CF056).


GAG_HV1YF Gag polyprotein (sprot)

A lentivirus-type gag polyprotein that is encoded in the genome of Human immunodeficiency virus type 1 group N (isolate YBF30).


POL_HV1YF Gag-Pol polyprotein (sprot)

A lentivirus-type gag-pol polyprotein that is encoded in the genome of Human immunodeficiency virus type 1 group N (isolate YBF30).


VIF_HV1YF Virion infectivity factor (sprot)


ENV_HV1YF Envelope glycoprotein gp160 (sprot)


GAG_HV1AN Gag polyprotein (sprot)

A lentivirus-type gag polyprotein that is encoded in the genome of Human immunodeficiency virus type 1 group O (isolate ANT70).


POL_HV1AN Gag-Pol polyprotein (sprot)

A lentivirus-type gag-pol polyprotein that is encoded in the genome of Human immunodeficiency virus type 1 group O (isolate ANT70).


VIF_HV1AN Virion infectivity factor (sprot)


ENV_HV1AN Envelope glycoprotein gp160 (sprot)


ENV_HV2BE Envelope glycoprotein gp160 (sprot)


GAG_HV2BE Gag polyprotein (sprot)

A lentivirus-type gag polyprotein that is encoded in the genome of Human immunodeficiency virus type 2 subtype A (isolate BEN).


POL_HV2BE Gag-Pol polyprotein (sprot)

A lentivirus-type gag-pol polyprotein that is encoded in the genome of Human immunodeficiency virus type 2 subtype A (isolate BEN).


VIF_HV2BE Virion infectivity factor (sprot)


A0A4D6K194_9VIRU Replication-associated protein (trembl)


A0A7U3NIG2_9ADEN E1B 55 kDa protein (trembl)


A0A7U3NII8_9ADEN Pre-hexon-linking protein IIIa (trembl)


A0A7U3NJL2_9ADEN Long fiber protein (trembl)


L_HMPVC RNA-directed RNA polymerase L (sprot)


VGLG_HMPVC Major surface glycoprotein G (sprot)


SH_HMPVC Small hydrophobic protein (sprot)


negative regulation of type I interferon production

Any process that stops, prevents, or reduces the frequency, rate, or extent of type I interferon production. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.


negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway

Any process that stops, prevents, or reduces the frequency, rate or extent of the series of a cytoplasmic pattern recognition receptor signaling pathway in response to a virus.


FUS_HMPVC Fusion glycoprotein F0 (sprot)


A0A0K1YWK9_9PAPI Major capsid protein L1 (trembl)


A0A0K1YWL0_9PAPI Minor capsid protein L2 (trembl)


A0A0K1YWP0_9PAPI Regulatory protein E2 (trembl)


A0A0K1YX24_9PAPI Replication protein E1 (trembl)


A3RKL8_9PAPI Replication protein E1 (trembl)


A3RKL9_9PAPI Regulatory protein E2 (trembl)


A3RKM1_9PAPI Minor capsid protein L2 (trembl)


A3RKM2_9PAPI Major capsid protein L1 (trembl)


C1ID86_9PAPI Replication protein E1 (trembl)


C1ID87_9PAPI Regulatory protein E2 (trembl)


C1ID89_9PAPI Minor capsid protein L2 (trembl)


C1ID90_9PAPI Major capsid protein L1 (trembl)


VL1_HPV11 Major capsid protein L1 (sprot)


VL2_HPV11 Minor capsid protein L2 (sprot)


VE1_HPV11 Replication protein E1 (sprot)


TPR domain binding

Binding to a tetratricopeptide repeat (TPR) domain of a protein, the consensus sequence of which is defined by a pattern of small and large hydrophobic amino acids and a structure composed of helices.


protein hexamerization

The formation of a protein hexamer, a macromolecular structure consisting of six noncovalently associated identical or nonidentical subunits.


C7B7D4_9PAPI Replication protein E1 (trembl)


C7B7D5_9PAPI Regulatory protein E2 (trembl)


C7B7D7_9PAPI Minor capsid protein L2 (trembl)


C7B7D8_9PAPI Major capsid protein L1 (trembl)


G5ELP1_9PAPI Replication protein E1 (trembl)


G5ELP2_9PAPI Regulatory protein E2 (trembl)


G5ELP4_9PAPI Minor capsid protein L2 (trembl)


G5ELP5_9PAPI Major capsid protein L1 (trembl)


E7BQA2_9PAPI Replication protein E1 (trembl)


E7BQA3_9PAPI Regulatory protein E2 (trembl)


E7BQA5_9PAPI Minor capsid protein L2 (trembl)


E7BQA6_9PAPI Major capsid protein L1 (trembl)


E7BQA9_9PAPI Replication protein E1 (trembl)


E7BQB0_9PAPI Regulatory protein E2 (trembl)


E7BQB2_9PAPI Minor capsid protein L2 (trembl)


E7BQB3_9PAPI Major capsid protein L1 (trembl)


I3P6K5_9PAPI Replication protein E1 (trembl)


I3P6K6_9PAPI Regulatory protein E2 (trembl)


I3P6K8_9PAPI Minor capsid protein L2 (trembl)


I3P6K9_9PAPI Major capsid protein L1 (trembl)


I6MRE3_9PAPI Replication protein E1 (trembl)


I6MRE4_9PAPI Regulatory protein E2 (trembl)


I6MRE6_9PAPI Minor capsid protein L2 (trembl)


I6MRE7_9PAPI Major capsid protein L1 (trembl)


VE1_HPV14 Replication protein E1 (sprot)


VL1_HPV14 Major capsid protein L1 (sprot)


VL2_HPV14 Minor capsid protein L2 (sprot)


I3P6M6_9PAPI Replication protein E1 (trembl)


I3P6M7_9PAPI Regulatory protein E2 (trembl)


I3P6M9_9PAPI Minor capsid protein L2 (trembl)


I3P6N0_9PAPI Major capsid protein L1 (trembl)


I6MRF0_9PAPI Replication protein E1 (trembl)


I6MRF1_9PAPI Regulatory protein E2 (trembl)


I6MRF3_9PAPI Minor capsid protein L2 (trembl)


I6MRF4_9PAPI Major capsid protein L1 (trembl)


I6MRF7_9PAPI Replication protein E1 (trembl)


I6MRF8_9PAPI Regulatory protein E2 (trembl)


I6MRG0_9PAPI Minor capsid protein L2 (trembl)


I6MRG1_9PAPI Major capsid protein L1 (trembl)


E7BQC4_9PAPI Replication protein E1 (trembl)


E7BQC5_9PAPI Regulatory protein E2 (trembl)


E7BQC7_9PAPI Minor capsid protein L2 (trembl)


E7BQC8_9PAPI Major capsid protein L1 (trembl)


A0A166FK25_9PAPI Replication protein E1 (trembl)


A0A166FK44_9PAPI Regulatory protein E2 (trembl)


A0A166FK53_9PAPI Minor capsid protein L2 (trembl)


A0A166FK68_9PAPI Major capsid protein L1 (trembl)


A0A166FKE6_9PAPI Replication protein E1 (trembl)


A0A166FKF4_9PAPI Regulatory protein E2 (trembl)


A0A166FKG3_9PAPI Minor capsid protein L2 (trembl)


A0A166FKH2_9PAPI Major capsid protein L1 (trembl)


K4MLH8_9PAPI Regulatory protein E2 (trembl)


K4MND1_9PAPI Major capsid protein L1 (trembl)


K4MNJ0_9PAPI Replication protein E1 (trembl)


K4MZ15_9PAPI Minor capsid protein L2 (trembl)


U6BME7_9PAPI Major capsid protein L1 (trembl)


U6BN97_9PAPI Regulatory protein E2 (trembl)


U6BNC2_9PAPI Minor capsid protein L2 (trembl)


U6BRB0_9PAPI Replication protein E1 (trembl)


K4MKV9_9PAPI Replication protein E1 (trembl)


K4MLH1_9PAPI Minor capsid protein L2 (trembl)


K4MNI4_9PAPI Regulatory protein E2 (trembl)


K4MZ08_9PAPI Major capsid protein L1 (trembl)


X2GB89_9PAPI Regulatory protein E2 (trembl)


X2GB93_9PAPI Minor capsid protein L2 (trembl)


X2GCR4_9PAPI Major capsid protein L1 (trembl)


X4Z137_9PAPI Replication protein E1 (trembl)


S6FS07_9PAPI Minor capsid protein L2 (trembl)


S6FWD4_9PAPI Major capsid protein L1 (trembl)


S6G0H0_9PAPI Replication protein E1 (trembl)


S6G386_9PAPI Regulatory protein E2 (trembl)


A0A2R2Q1V7_9PAPI Replication protein E1 (trembl)


A0A2R2Q213_9PAPI Minor capsid protein L2 (trembl)


A0A2R2Q217_9PAPI Regulatory protein E2 (trembl)


A0A2R2Q240_9PAPI Major capsid protein L1 (trembl)


A0A0N9E0S6_9PAPI Regulatory protein E2 (trembl)


A0A0N9E2B5_9PAPI Replication protein E1 (trembl)


A0A0N9E2M0_9PAPI Major capsid protein L1 (trembl)


A0A0N9E2S0_9PAPI Minor capsid protein L2 (trembl)


A0A0H4LMI6_9PAPI Replication protein E1 (trembl)


A0A0H4LNY2_9PAPI Minor capsid protein L2 (trembl)


A0A0H4LQV7_9PAPI Major capsid protein L1 (trembl)


A0A0H4M3P8_9PAPI Regulatory protein E2 (trembl)


A0A0H4LMJ3_9PAPI Minor capsid protein L2 (trembl)


A0A0H4LNY6_9PAPI Regulatory protein E2 (trembl)


A0A0H4LSW2_9PAPI Replication protein E1 (trembl)


A0A0H4M3Q7_9PAPI Major capsid protein L1 (trembl)


A0A0F7GFM9_9PAPI Replication protein E1 (trembl)


A0A0F7GFW4_9PAPI Regulatory protein E2 (trembl)


A0A0F7GGZ0_9PAPI Major capsid protein L1 (trembl)


A0A0F7GHA1_9PAPI Minor capsid protein L2 (trembl)


A0A166FK94_9PAPI Replication protein E1 (trembl)


A0A166FKA1_9PAPI Regulatory protein E2 (trembl)


A0A166FKB2_9PAPI Minor capsid protein L2 (trembl)


A0A166FKC2_9PAPI Major capsid protein L1 (trembl)


VE1_HPV21 Replication protein E1 (sprot)


VL1_HPV21 Major capsid protein L1 (sprot)


VL2_HPV21 Minor capsid protein L2 (sprot)


VE1_HPV22 Replication protein E1 (sprot)


VL1_HPV22 Major capsid protein L1 (sprot)


VL2_HPV22 Minor capsid protein L2 (sprot)


VE1_HPV23 Replication protein E1 (sprot)


VL1_HPV23 Major capsid protein L1 (sprot)


VL2_HPV23 Minor capsid protein L2 (sprot)


VE1_HPV24 Replication protein E1 (sprot)


VL1_HPV24 Major capsid protein L1 (sprot)


VL2_HPV24 Minor capsid protein L2 (sprot)


VE1_HPV27 Replication protein E1 (sprot)


VL1_HPV27 Major capsid protein L1 (sprot)


VL2_HPV27 Minor capsid protein L2 (sprot)


VE1_HPV29 Replication protein E1 (sprot)


VL1_HPV29 Major capsid protein L1 (sprot)


VL2_HPV29 Minor capsid protein L2 (sprot)


VE1_HPV31 Replication protein E1 (sprot)


PDZ domain binding

Binding to a PDZ domain of a protein, a domain found in diverse signaling proteins.


VL1_HPV31 Major capsid protein L1 (sprot)


VL2_HPV31 Minor capsid protein L2 (sprot)


VE1_HPV35 Replication protein E1 (sprot)


VL1_HPV35 Major capsid protein L1 (sprot)


VL2_HPV35 Minor capsid protein L2 (sprot)


VE1_HPV04 Replication protein E1 (sprot)


VL1_HPV04 Major capsid protein L1 (sprot)


VL2_HPV04 Minor capsid protein L2 (sprot)


VL1_HPV44 Major capsid protein L1 (sprot)


Q6LCS2_HPV44 E4 protein (Fragment) (trembl)


VE1_HPV44 Replication protein E1 (sprot)


VL2_HPV44 Minor capsid protein L2 (sprot)


VL1_HPV05 Major capsid protein L1 (sprot)


VL2_HPV05 Minor capsid protein L2 (sprot)


VE1_HPV05 Replication protein E1 (sprot)


A0A0P0E628_HPV51 Regulatory protein E2 (trembl)


A0A0P0ESU6_HPV51 Replication protein E1 (trembl)


C9EF16_HPV51 Major capsid protein L1 (trembl)


C9EF17_HPV51 Minor capsid protein L2 (trembl)


D0EDB7_HPV52 Replication protein E1 (trembl)


D0EDB8_HPV52 Regulatory protein E2 (trembl)


D0EDB9_HPV52 Minor capsid protein L2 (trembl)


D0EDC0_HPV52 Major capsid protein L1 (trembl)


VL1_HPV56 Major capsid protein L1 (sprot)


VL2_HPV56 Minor capsid protein L2 (sprot)


B6ZB00_HPV58 Replication protein E1 (trembl)


B6ZB11_HPV58 Probable protein E5 (trembl)


F1B8Y7_HPV58 Major capsid protein L1 (trembl)


F8S5E7_HPV58 Regulatory protein E2 (trembl)


F8S5F0_HPV58 Minor capsid protein L2 (trembl)


B9UPE1_HPV59 Replication protein E1 (trembl)


B9UPE2_HPV59 Regulatory protein E2 (trembl)


B9UPE5_HPV59 Minor capsid protein L2 (trembl)


Q81969_HPV59 Probable protein E5 (trembl)


Q81971_HPV59 Major capsid protein L1 (trembl)


VL1_HPV62 Major capsid protein L1 (sprot)


VL2_HPV62 Minor capsid protein L2 (sprot)


Q676U9_HPV62 Regulatory protein E2 (trembl)


Q676V0_HPV62 Replication protein E1 (trembl)


A9XCT5_HPV66 Regulatory protein E2 (trembl)


A9XCT7_HPV66 Minor capsid protein L2 (trembl)


A9XCU8_HPV66 Replication protein E1 (trembl)


A9XCV2_HPV66 Major capsid protein L1 (trembl)


VL2_HPV07 Minor capsid protein L2 (sprot)


VE1_HPV07 Replication protein E1 (sprot)


VL1_HPV07 Major capsid protein L1 (sprot)


VE1_HPV73 Replication protein E1 (sprot)


Q82008_HPV73 Regulatory protein E2 (trembl)


Q82009_HPV73 Minor capsid protein L2 (trembl)


Q82010_HPV73 Major capsid protein L1 (trembl)


VL1_HPV82 Major capsid protein L1 (sprot)


VL2_HPV82 Minor capsid protein L2 (sprot)


Q9IR54_HPV82 Probable protein E5 (Fragment) (trembl)


Q9IR56_HPV82 Regulatory protein E2 (trembl)


Q9IR57_HPV82 Replication protein E1 (trembl)


VL2_HPV09 Minor capsid protein L2 (sprot)


VL1_HPV09 Major capsid protein L1 (sprot)


VE1_HPV09 Replication protein E1 (sprot)


K4MKX9_9PAPI Major capsid protein L1 (trembl)


K4MLI6_9PAPI Regulatory protein E2 (trembl)


K4MND8_9PAPI Minor capsid protein L2 (trembl)


K4MNK6_9PAPI Replication protein E1 (trembl)


VL1_HPV1 Major capsid protein L1 (sprot)


VL2_HPV1 Minor capsid protein L2 (sprot)


VE1_HPV10 Replication protein E1 (sprot)


VL1_HPV10 Major capsid protein L1 (sprot)


VL2_HPV10 Minor capsid protein L2 (sprot)


Q81958_HPV10 Major capsid protein L1 (Fragment) (trembl)


D3VWB8_9PAPI Replication protein E1 (trembl)


D3VWB9_9PAPI Regulatory protein E2 (trembl)


D3VWC1_9PAPI Minor capsid protein L2 (trembl)


D3VWC2_9PAPI Major capsid protein L1 (trembl)


E7BRQ9_9PAPI Replication protein E1 (trembl)


E7BRR0_9PAPI Regulatory protein E2 (trembl)


E7BRR2_9PAPI Minor capsid protein L2 (trembl)


E7BRR3_9PAPI Major capsid protein L1 (trembl)


E7BRR6_9PAPI Replication protein E1 (trembl)


E7BRR7_9PAPI Regulatory protein E2 (trembl)


E7BRR9_9PAPI Minor capsid protein L2 (trembl)


E7BRS0_9PAPI Major capsid protein L1 (trembl)


E7BQ88_9PAPI Replication protein E1 (trembl)


E7BQ89_9PAPI Regulatory protein E2 (trembl)


E7BQ91_9PAPI Minor capsid protein L2 (trembl)


E7BQ92_9PAPI Major capsid protein L1 (trembl)


I3P6L9_9PAPI Replication protein E1 (trembl)


I3P6M0_9PAPI Regulatory protein E2 (trembl)


I3P6M2_9PAPI Minor capsid protein L2 (trembl)


I3P6M3_9PAPI Major capsid protein L1 (trembl)


I3P6P7_9PAPI Replication protein E1 (trembl)


I3P6P8_9PAPI Regulatory protein E2 (trembl)


I3P6Q0_9PAPI Minor capsid protein L2 (trembl)


I3P6Q1_9PAPI Major capsid protein L1 (trembl)


VL1_HPV16 Major capsid protein L1 (sprot)


VL2_HPV16 Minor capsid protein L2 (sprot)


VE1_HPV16 Replication protein E1 (sprot)


VE2_HPV16 Regulatory protein E2 (sprot)

A protein that is a translation product of the E2 gene in Human papillomavirus type 16.


VE6_HPV16 Protein E6 (sprot)

A protein that is a translation product of the E6 gene in Human papillomavirus type 16.


suppression by virus of host transcription

Any process in which a virus stops, prevents, or reduces the activity of host DNA-dependent transcription; the cellular synthesis of RNA on a template of DNA. Viral proteins can interfere with either host RNA polymerase or with transcription factors.


activation of GTPase activity

Any process that initiates the activity of an inactive GTPase through the replacement of GDP by GTP.


cadmium ion binding

Binding to a cadmium ion (Cd).


positive regulation of actin filament polymerization

Any process that activates or increases the frequency, rate or extent of actin polymerization.


disruption by virus of host JAK-STAT cascade via inhibition of host IRF9 activity

Any process in which a virus interferes with a JAK1-STAT signaling cascade in a host organism by reducing the activity of host IRF9 (interferon regulatory factor-9), a transcription factor involved in the innate immune response. Viral infection triggers binding of IRF9 to phosphorylated STAT1 and STAT2, forming the ISGF3 complex. The ISGF3 complex migrates to the nucleus and activates transcription of IFN-responsive genes.


K4MKV2_9PAPI Regulatory protein E2 (trembl)


K4MLG5_9PAPI Major capsid protein L1 (trembl)


K4MNB0_9PAPI Replication protein E1 (trembl)


K4MNH8_9PAPI Minor capsid protein L2 (trembl)


VE1_HPV18 Replication protein E1 (sprot)


VL2_HPV18 Minor capsid protein L2 (sprot)


VL1_HPV18 Major capsid protein L1 (sprot)


A0A2S0BE72_9PAPI Major capsid protein L1 (trembl)


A0A2S0BE73_9PAPI Regulatory protein E2 (trembl)


A0A2S0BE77_9PAPI Minor capsid protein L2 (trembl)


A0A2S0BFM6_9PAPI Replication protein E1 (trembl)


VE1_HPV26 Replication protein E1 (sprot)


VL1_HPV26 Major capsid protein L1 (sprot)


VL2_HPV26 Minor capsid protein L2 (sprot)


VE1_HPV32 Replication protein E1 (sprot)


VL1_HPV32 Major capsid protein L1 (sprot)


VL2_HPV32 Minor capsid protein L2 (sprot)


A0A0P0E4T0_HPV34 Regulatory protein E2 (trembl)


A0A0P0EAC3_HPV34 Minor capsid protein L2 (trembl)


A0A0P0EF83_HPV34 Major capsid protein L1 (trembl)


A0A0P0F0K8_HPV34 Probable protein E5 (trembl)


A0A0P0F0M0_HPV34 Replication protein E1 (trembl)


VE1_HPV41 Replication protein E1 (sprot)


VL1_HPV41 Major capsid protein L1 (sprot)


VL2_HPV41 Minor capsid protein L2 (sprot)


VL1_HPV48 Major capsid protein L1 (sprot)


VE1_HPV48 Replication protein E1 (sprot)


VL2_HPV48 Minor capsid protein L2 (sprot)


VL1_HPV50 Major capsid protein L1 (sprot)


Q80929_HPV50 Replication protein E1 (trembl)


VL2_HPV50 Minor capsid protein L2 (sprot)


VL2_HPV53 Minor capsid protein L2 (sprot)


VL1_HPV53 Major capsid protein L1 (sprot)


A0A0P0E686_HPV54 Major capsid protein L1 (trembl)


A0A0P0ERV7_HPV54 Replication protein E1 (trembl)


A0A0P0F0V1_HPV54 Minor capsid protein L2 (trembl)


A0A0P0F229_HPV54 Regulatory protein E2 (trembl)


VL1_HPV60 Major capsid protein L1 (sprot)


VE1_HPV60 Replication protein E1 (sprot)


VL2_HPV60 Minor capsid protein L2 (sprot)


VL1_HPV61 Major capsid protein L1 (sprot)


VE1_HPV61 Replication protein E1 (sprot)


VL2_HPV61 Minor capsid protein L2 (sprot)


VE1_HPV63 Replication protein E1 (sprot)


VL1_HPV63 Major capsid protein L1 (sprot)


VL2_HPV63 Minor capsid protein L2 (sprot)


VE1_HPV70 Replication protein E1 (sprot)


VL1_HPV70 Major capsid protein L1 (sprot)


VL2_HPV70 Minor capsid protein L2 (sprot)


A0A059U7K1_HPV72 Regulatory protein E2 (trembl)


A0A059U7K4_HPV72 Minor capsid protein L2 (trembl)


A0A059UAS1_HPV72 Replication protein E1 (trembl)


A0A059UAS5_HPV72 Major capsid protein L1 (trembl)


A8R8N1_9PAPI Replication protein E1 (trembl)


A8R8N3_9PAPI Regulatory protein E2 (trembl)


A8R8N5_9PAPI Minor capsid protein L2 (trembl)


A8R8N7_9PAPI Major capsid protein L1 (trembl)


Q8JN95_9PAPI Major capsid protein L1 (trembl)


Q8JN96_9PAPI Minor capsid protein L2 (trembl)


Q8JN98_9PAPI Regulatory protein E2 (trembl)


Q8JN99_9PAPI Replication protein E1 (trembl)


Q6TY23_9PAPI Major capsid protein L1 (trembl)


Q6TY24_9PAPI Minor capsid protein L2 (trembl)


Q6TY26_9PAPI Regulatory protein E2 (trembl)


Q6TY27_9PAPI Replication protein E1 (trembl)


L7YAW4_9PAPI Minor capsid protein L2 (trembl)


L7YF18_9PAPI Replication protein E1 (trembl)


L7YGU6_9PAPI Major capsid protein L1 (trembl)


L7YIA1_9PAPI Regulatory protein E2 (trembl)


V_PI2HT Non-structural protein V (sprot)


FUS_PI2HT Fusion glycoprotein F0 (sprot)


L_PI2HT RNA-directed RNA polymerase L (sprot)


D7US57_9MONO Non-structural protein V (trembl)


D7US59_9MONO Fusion glycoprotein F0 (trembl)


D7US61_9MONO RNA-directed RNA polymerase L (trembl)


11K_PAVHV Host-modulation protein 11K (sprot)


CAPSD_PAVHV Minor capsid protein VP1 (sprot)


rolling hairpin viral DNA replication

A viral DNA replication process where a 3' hairpin structure in the viral single-stranded DNA (ssDNA) template serves as a primer for host enzymes to synthesize DNA.


RDRP_HPBVH Potential RNA-dependent RNA polymerase (sprot)


CAPSD_HPBVH Capsid protein precursor (sprot)


A0A0S2C4E4_9VIRU Replication-associated protein (trembl)


M4SP12_9POLY Minor capsid protein (trembl)


M4SQ02_9POLY Minor capsid protein VP2 (trembl)


M4T5D3_9POLY Capsid protein VP1 (trembl)


E9NQ88_9POLY Minor capsid protein (trembl)


E9NQ89_9POLY Minor capsid protein (trembl)


E9NQ90_9POLY Capsid protein VP1 (trembl)


SH_HRSVB Small hydrophobic protein (sprot)


GLYC_HRSVB Major surface glycoprotein G (sprot)


FUS_HRSVB Fusion glycoprotein F0 (sprot)


L_HRSVB RNA-directed RNA polymerase L (sprot)


NS2_HRSVB Non-structural protein 2 (sprot)


NS1_HRSVB Non-structural protein 1 (sprot)


A0A023PFZ0_9MONO Fusion glycoprotein F0 (trembl)


A0A023PIG4_9MONO RNA-directed RNA polymerase L (trembl)


ENV_FOAMV Envelope glycoprotein gp130 (sprot)


D4N3R0_9CIRC Replication-associated protein (trembl)


Q6JE41_9BROM RNA-directed RNA polymerase 2a (trembl)


Q6JE42_9BROM Replication protein 1a (trembl)


A0A6J3U7A3_9GEMI Transcriptional activator protein (trembl)


A0A6J3U7B5_9GEMI Replication-associated protein (trembl)


A0A6J3U7B7_9GEMI Movement protein BC1 (trembl)


A0A6J3U7C0_9GEMI Nuclear shuttle protein (trembl)


A0A6J3UEJ1_9GEMI Replication enhancer (trembl)


A0A6J3UEJ3_9GEMI Capsid protein (trembl)


B3VKH1_9VIRU Replicase polyprotein (trembl)


B3VKH2_9VIRU Triple gene block 1 (trembl)


B3VKH3_9VIRU Movement protein TGB2 (trembl)


B3VKH4_9VIRU Movement protein TGBp3 (trembl)


B3VKH6_9VIRU RNA silencing suppressor (trembl)


Q5DKR0_9VIRU Movement protein TGBp3 (trembl)


Q5DKR1_9VIRU Triple gene block protein (trembl)


Q5DKR2_9VIRU Triple gene block protein (trembl)


Q5DKR3_9VIRU RNA replication protein (trembl)


A0A7U3S2Z6_9MONO RNA-directed RNA polymerase (trembl)


A0A7D7F0U3_9MONO Nucleocapsid protein (trembl)


A0A7D7F1B6_9MONO RNA-directed RNA polymerase (trembl)


S5RC76_9VIRU Putative coat protein (trembl)


S5RZ23_9VIRU Replication-associated protein (trembl)


I1ST80_9VIRU RNA-directed RNA polymerase L (trembl)


I1ST82_9VIRU Envelopment polyprotein (trembl)


DUT_ICHVA Deoxyuridine 5'-triphosphate nucleotidohydrolase (sprot)


HELI_ICHVA Probable ATP-dependent helicase 25 (sprot)


VG06_ICHVA Putative membrane protein ORF6 (sprot)


VG46_ICHVA Probable major glycoprotein (sprot)


VG01_ICHVA Uncharacterized protein ORF1 (sprot)


VG07_ICHVA Putative membrane protein ORF7 (sprot)


VG10_ICHVA Putative membrane protein ORF10 (sprot)


VG51_ICHVA Putative membrane protein ORF51 (sprot)


VG19_ICHVA Putative membrane protein ORF19 (sprot)


VG08_ICHVA Putative membrane protein ORF8 (sprot)


VG59_ICHVA Putative membrane protein ORF59 (sprot)


VG47_ICHVA Subtilisin-like protease (sprot)


peptide hormone processing

The generation of a mature peptide hormone by posttranslational processing of a prohormone.


VTER_ICHVA Probable DNA-packaging protein (sprot)


VG63_ICHVA Uncharacterized protein ORF63 (sprot)


VG09_ICHVA Putative zinc-binding protein ORF9 (sprot)


VG11_ICHVA Putative zinc-binding protein ORF11 (sprot)


VG12_ICHVA Putative zinc-binding protein ORF12 (sprot)


VG78_ICHVA Putative zinc-binding protein ORF78 (sprot)


A0A2H4YQ30_9VIRU ATP-dependent helicase Rep (trembl)


A0A2H4YQ33_9VIRU Capsid protein (trembl)


A0A075IFP0_9VIRU Envelopment polyprotein (trembl)


A0A075IK44_9VIRU RNA-directed RNA polymerase L (trembl)


B5WYM7_9VIRU RNA-directed RNA polymerase (trembl)


TRAP_ICMV Transcriptional activator protein (sprot)


REN_ICMV Replication enhancer protein (sprot)


NSP_ICMV Nuclear shuttle protein (sprot)


REP_ICMV Replication-associated protein (sprot)


Q7TAS7_ICMV Replication-associated protein (trembl)


Q7TAS8_ICMV Replication enhancer (trembl)


TGB3_ICRSV Movement protein TGBp3 (sprot)


TGB2_ICRSV Movement protein TGB2 (sprot)


TGB1_ICRSV Movement and silencing protein TGBp1 (sprot)


RDRP_ICRSV RNA replication protein (sprot)


A0A1N7TEH5_9CIRC Replication-associated protein (trembl)


L_IHNVW RNA-directed RNA polymerase L (sprot)


Q9IBP5_IHHNV 37 kDa coat protein (trembl)


Q9IBP6_IHHNV Non-structural protein (trembl)


A9Y5Q7_ILTV Packaging protein UL32 (trembl)


A9Y5V7_ILTV Envelope glycoprotein M (trembl)


A9Y600_ILTV Envelope glycoprotein B (trembl)


F5B4Q4_ILTV Membrane protein UL56 (trembl)


F5B4Q7_ILTV Envelope glycoprotein K (trembl)


F5B4Q8_ILTV Helicase-primase primase subunit (trembl)


F5B4S4_ILTV Capsid vertex component 2 (trembl)


F5B4S5_ILTV Capsid scaffolding protein (trembl)


F5B4S9_ILTV Major DNA-binding protein (trembl)


F5B4T4_ILTV Nuclear egress protein 2 (trembl)


F5B4T6_ILTV Large tegument protein (trembl)


F5B4T7_ILTV Tegument protein UL37 (trembl)


F5B4T8_ILTV Triplex capsid protein 1 (trembl)


F5B4T9_ILTV Ribonucleoside-diphosphate reductase large subunit (trembl)


F5B4U0_ILTV Ribonucleoside-diphosphate reductase small subunit (trembl)


F5B4U1_ILTV Virion host shutoff protein (trembl)


F5B4U3_ILTV Envelope protein UL43 (trembl)


F5B4U7_ILTV Major capsid protein (trembl)


F5B4W0_ILTV DNA replication helicase (trembl)


F5B4X2_ILTV Serine/threonine protein kinase US3 (trembl)


F5B4X5_ILTV Envelope glycoprotein J (trembl)


G3CEX1_ILTV Multifunctional expression regulator (trembl)


G3CEZ2_ILTV Tripartite terminase subunit 1 (trembl)


G3CF29_ILTV Envelope glycoprotein L (trembl)


O56867_ILTV Envelope glycoprotein N (trembl)


O56868_ILTV Tegument protein VP22 (trembl)


O56869_ILTV Alpha trans-inducing protein (trembl)


O56870_ILTV Putative viral tegument protein (trembl)


O56871_ILTV Membrane protein UL45 (trembl)


O56877_ILTV Envelope glycoprotein H (trembl)


O56880_ILTV Nucleocapsid protein (trembl)


Q0PEE1_ILTV Envelope glycoprotein E (trembl)


Q3ZU93_ILTV Nuclear egress protein 1 (trembl)


Q67628_ILTV Envelope glycoprotein C (trembl)


Q67642_ILTV Envelope glycoprotein (trembl)


Q67644_ILTV Envelope glycoprotein D (trembl)


Q67645_ILTV Envelope glycoprotein I (trembl)


Q98105_ILTV Nuclear protein UL4 (trembl)


Q98107_ILTV Nuclear protein UL3 (trembl)


Q98108_ILTV Uracil-DNA glycosylase (trembl)


Q9QCD9_ILTV Deoxyuridine 5'-triphosphate nucleotidohydrolase (trembl)


Q9QCE0_ILTV Tegument protein UL51 (trembl)


Q9QH59_ILTV Tripartite terminase subunit 2 (trembl)


Q9QP11_ILTV DNA helicase/primase complex-associated protein (trembl)


Q9QP12_ILTV Replication origin-binding protein (trembl)


Q9QP17_ILTV Tegument protein UL14 (trembl)


Q9QP18_ILTV Capsid vertex component 1 (trembl)


Q9QP19_ILTV Tripartite terminase subunit 3 (trembl)


Q9QP20_ILTV Triplex capsid protein 2 (trembl)


Q9QP22_ILTV Envelope protein UL20 (trembl)


POLS_IPNVJ Structural polyprotein (sprot)


RDRP_IPNVJ RNA-directed RNA polymerase (sprot)


PB2_ISAV8 Polymerase basic protein 2 (sprot)


RDRP_ISAV8 RNA-directed RNA polymerase catalytic subunit (sprot)


FUS_ISAV8 Fusion glycoprotein F0 (sprot)


NEP_ISAV8 Nuclear export protein (sprot)


NS1_ISAV8 Non-structural protein 1 (sprot)


A0A140G0I4_ISKNV NIF-NLI interacting factor (trembl)


A0A140G0I7_ISKNV Myristylated membrane protein (trembl)


A0A140G0I8_ISKNV RING-finger-containing E3 ubiquitin ligase (trembl)


A0A140G0J9_ISKNV Macro domain-containing protein (trembl)


A0A140G0K7_ISKNV DNA repair protein RAD2 (trembl)


A0A140G0K8_ISKNV DNA-directed RNA polymerase subunit (trembl)


A0A140G0L3_ISKNV Deoxyribonucleoside kinase (trembl)


A0A140G0M3_ISKNV Sulfhydryl oxidase (trembl)


A0A140G0M6_ISKNV Cytosine DNA methyltransferase (trembl)


A0A140G0N0_ISKNV PDGF/VEGF-like protein (trembl)


A0A140G0N9_ISKNV Replication factor (trembl)


A0A140G0P0_ISKNV DNA-binding protein (trembl)


A0A140G0R9_ISKNV RING-finger domain-containing E3 protein (trembl)


A0A140G0S2_ISKNV Ankyrin repeat-containing protein (trembl)


A0A140G0S3_ISKNV Suppressor of cytokine signaling 1 (trembl)


Modulates the activity of the enzyme 1-phosphatidylinositol-3-kinase activity.


phosphatidylinositol 3-kinase complex

A protein complex capable of phosphatidylinositol 3-kinase activity and containing subunits of any phosphatidylinositol 3-kinase (PI3K) enzyme. These complexes are divided in three classes (called I, II and III) that differ for their presence across taxonomic groups and for the type of their constituents. Catalytic subunits of phosphatidylinositol 3-kinase enzymes are present in all 3 classes; regulatory subunits of phosphatidylinositol 3-kinase enzymes are present in classes I and III; adaptor proteins have been observed in class II complexes and may be present in other classes too.


A0A140G0U3_ISKNV Serine-threonine protein kinase (trembl)


A0A140G0V1_ISKNV Myristylated membrane protein (trembl)


A0A140G0V6_ISKNV D5 family NTPase (trembl)


A0A140G0V7_ISKNV Tumor necrosis factor receptor-associated factor (trembl)


protein K63-linked ubiquitination

A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 63 of the ubiquitin monomers, is added to a protein. K63-linked ubiquitination does not target the substrate protein for degradation, but is involved in several pathways, notably as a signal to promote error-free DNA postreplication repair.


A0A7T1KQX3_ISKNV Ribonucleoside-diphosphate reductase small chain (trembl)


A0A7T1KR03_ISKNV Ankyrin repeat-containing protein (trembl)


A0A7T1KR04_ISKNV RING-finger-containing E3 ubiquitin ligase (trembl)


A0A7U1BJA1_ISKNV DNA-directed RNA polymerase subunit beta (trembl)


A0A7U1BJK0_ISKNV Ribonuclease III (trembl)


A0A7U3WA50_ISKNV SNF2 family helicase (trembl)


A0A7U3WA51_ISKNV mRNA guanylyltransferase (trembl)


A0A7U3WA52_ISKNV RING-type E3 ubiquitin transferase (trembl)


A0A7U3WAA2_ISKNV Ankyrin repeat-containing protein (trembl)


A0A7U3WAB1_ISKNV Caspace recruitment domain-containing protein (trembl)


A0A8H2SJ73_ISKNV Transmembrane amino acid transporter protein (trembl)


L-amino acid transmembrane transporter activity

Enables the transfer of an L-amino acid from one side of a membrane to the other. L-amino acids are the L-enantiomers of amino acids.


A0A8H2SJ93_ISKNV DNA polymerase (trembl)


A0A8H2SJI3_ISKNV Tyrosine kinase (trembl)


A0A8H2SJL8_ISKNV Laminin-type epidermal growth factor-like protein (trembl)


Q8V5D9_ISKNV Major capsid protein (trembl)


Q77HV9_ISKNN Major capsid protein (trembl)


Q8QUJ9_ISKNN Putative tumor necrosis factor receptor associated factor (trembl)


Q8QUM3_ISKNN Putative ribonuclease (trembl)


Q8QUN3_ISKNN Putative ankyrin repeat protein (trembl)


Q8QUP5_ISKNN RING-type E3 ubiquitin transferase (trembl)


Q8QUP6_ISKNN mRNA guanylyltransferase (trembl)


Q8QUR4_ISKNN Putative cytosine DNA methyltransferase (trembl)


Q8QUR7_ISKNN Sulfhydryl oxidase (trembl)


Q8QUS6_ISKNN DNA-directed RNA polymerase subunit beta (trembl)


Q8QUS8_ISKNN Putative thymidine kinase (trembl)


Q8QUT2_ISKNN DNA-directed RNA polymerase subunit (trembl)


Q8QUT3_ISKNN Putative DNA repair protein (trembl)


Q8QUT6_ISKNN Ribonucleoside-diphosphate reductase small chain (trembl)


Q8QUU8_ISKNN Putative zinc finger protein (trembl)


F8IZY3_9INFA Nuclear export protein (trembl)


F8IZY4_9INFA Non-structural protein 1 (trembl)


F8IZY5_9INFA Nuclear export protein (trembl)


F8IZY6_9INFA Non-structural protein 1 (trembl)


F8IZY7_9INFA Polymerase acidic protein (trembl)


F8IZY8_9INFA Protein PA-X (Fragment) (trembl)


F8IZY9_9INFA RNA-directed RNA polymerase catalytic subunit (trembl)


F8IZZ0_9INFA RNA-directed RNA polymerase catalytic subunit (Fragment) (trembl)


F8IZZ1_9INFA Polymerase basic protein 2 (trembl)


F8IZZ2_9INFA Polymerase basic protein 2 (Fragment) (trembl)


A0A024E270_9INFA Matrix protein 2 (trembl)


proton transmembrane transporter activity

Enables the transfer of a proton from one side of a membrane to the other.


A0A024E276_9INFA Polymerase acidic protein (trembl)


apical plasma membrane

The region of the plasma membrane located at the apical end of the cell.


A0A024E2L1_9INFA Non-structural protein 1 (trembl)


A0A024E2L4_9INFA Polymerase basic protein 2 (trembl)


A0A024E384_9INFA RNA-directed RNA polymerase catalytic subunit (trembl)


A0A024E3W8_9INFA Matrix protein 1 (trembl)


A0A024E3X3_9INFA Nuclear export protein (trembl)


K9NVC5_9INFA Non-structural protein 1 (trembl)


K9NW72_9INFA RNA-directed RNA polymerase catalytic subunit (trembl)


K9NWJ7_9INFA Nuclear export protein (trembl)


K9NXD3_9INFA Polymerase acidic protein (trembl)


K9NXN0_9INFA Polymerase basic protein 2 (trembl)


Q6VE54_9INFA Non-structural protein 1 (trembl)


Q6VE58_9INFA Polymerase acidic protein (trembl)


Q6VE63_9INFA Polymerase basic protein 2 (Fragment) (trembl)


Q6VGI3_9INFA RNA-directed RNA polymerase catalytic subunit (trembl)


A0A024B7J6_9INFA RNA-directed RNA polymerase catalytic subunit (trembl)


A0A024B7K1_9INFA Polymerase basic protein 2 (trembl)


A0A024B7Q4_9INFA RNA-directed RNA polymerase catalytic subunit (Fragment) (trembl)


A0A024B830_9INFA Hemagglutinin (Fragment) (trembl)


A0A024B8E3_9INFA Neuraminidase (Fragment) (trembl)


A0A024B8E6_9INFA Protein PB1-F2 (trembl)


D1CLZ6_9INFA Polymerase basic protein 2 (trembl)


C4LMB8_9INFA Polymerase basic protein 2 (trembl)


C4LMB9_9INFA RNA-directed RNA polymerase catalytic subunit (trembl)


C4LMC1_9INFA Polymerase acidic protein (trembl)


C4LMC7_9INFA Nuclear export protein (trembl)


C4LMC8_9INFA Non-structural protein 1 (trembl)


H6QM90_9INFA Polymerase basic protein 2 (trembl)


H6QM91_9INFA RNA-directed RNA polymerase catalytic subunit (trembl)


H6QM92_9INFA Polymerase acidic protein (trembl)


H6QM93_9INFA Hemagglutinin (trembl)

A hemagglutinin subtype H17 (Influenza A virus) that is encoded in the genome of the H17N10 strain A/little yellow-shouldered bat/Guatemala/060/2010.


H6QM98_9INFA Nuclear export protein (trembl)


H6QM99_9INFA Non-structural protein 1 (trembl)


G7WVG9_9INFA Nuclear export protein (trembl)


G7WVH0_9INFA Non-structural protein 1 (trembl)


G7WVH1_9INFA Polymerase acidic protein (trembl)


G7WVH2_9INFA Polymerase basic protein 2 (trembl)


G7WWQ3_9INFA Nuclear export protein (trembl)


G7WWQ4_9INFA Non-structural protein 1 (trembl)


G7WWQ5_9INFA Polymerase acidic protein (trembl)


G7WWQ6_9INFA RNA-directed RNA polymerase catalytic subunit (trembl)


G7WWQ8_9INFA Polymerase basic protein 2 (trembl)


Q5Q153_9INFA RNA-directed RNA polymerase catalytic subunit (trembl)


Q5Q154_9INFA Polymerase basic protein 2 (Fragment) (trembl)


Q5Q155_9INFA Polymerase acidic protein (trembl)


Q5Q156_9INFA Non-structural protein 1 (trembl)


B5LBD8_9INFA Polymerase acidic protein (trembl)


B5LBE0_9INFA Nucleocapsid protein (Fragment) (trembl)


B5LBE1_9INFA Neuraminidase (Fragment) (trembl)


B5LBE4_9INFA Nuclear export protein (trembl)


O41667_9INFA Non-structural protein 1 (trembl)


Q0A2B1_9INFA Polymerase basic protein 2 (trembl)


Q0A2B3_9INFA RNA-directed RNA polymerase catalytic subunit (trembl)


D1LNT4_I63A3 Hemagglutinin (Fragment) (trembl)


D1LNT7_I63A3 Neuraminidase (Fragment) (trembl)


D1LNT9_I63A3 Nuclear export protein (trembl)


D1LNU0_I63A3 Non-structural protein 1 (trembl)


D1LNU3_I63A3 Polymerase PB2 (Fragment) (trembl)


Q20P18_I63A3 RNA-directed RNA polymerase catalytic subunit (trembl)


Q20P19_I63A3 Polymerase acidic protein (trembl)


PAX_I96A0 Protein PA-X (sprot)

An influenza A virus protein PA-X that is encoded in the genome of the H5N1 strain A/Goose/Guangdong/1/1996 genotype Gs/Gd.


NS1_I96A0 Non-structural protein 1 (sprot)

An influenzavirus non-structural protein 1 that is encoded in the genome of the H5N1 strain A/Goose/Guangdong/1/1996 genotype Gs/Gd.


NEP_I96A0 Nuclear export protein (sprot)

An influenzavirus nuclear export protein that is encoded in the genome of the H5N1 strain A/Goose/Guangdong/1/1996 genotype Gs/Gd.


M1_I96A0 Matrix protein 1 (sprot)

An influenzavirus matrix protein 1 that is encoded in the genome of the H5N1 strain A/Goose/Guangdong/1/1996 genotype Gs/Gd.


M2_I96A0 Matrix protein 2 (sprot)

An influenzavirus matrix protein 2 that is encoded in the genome of the H5N1 strain A/Goose/Guangdong/1/1996 genotype Gs/Gd.


NCAP_I96A0 Nucleoprotein (sprot)

A nucleoprotein (Influenza A virus) that is encoded in the genome of the H5N1 strain A/Goose/Guangdong/1/1996 genotype Gs/Gd.


PA_I96A0 Polymerase acidic protein (sprot)

An influenza A virus polymerase acidic protein that is encoded in the genome of the H5N1 strain A/Goose/Guangdong/1/1996 genotype Gs/Gd.


RDRP_I96A0 RNA-directed RNA polymerase catalytic subunit (sprot)


PB2_I96A0 Polymerase basic protein 2 (sprot)

A polymerase basic protein 2 (Influenza A virus) that is encoded in the genome of the H5N1 strain A/Goose/Guangdong/1/1996 genotype Gs/Gd.


PB2_I34A1 Polymerase basic protein 2 (sprot)

A polymerase basic protein 2 (Influenza A virus) that is encoded in the genome of the H1N1 strain A/Puerto Rico/8/1934.


RDRP_I34A1 RNA-directed RNA polymerase catalytic subunit (sprot)

An RNA-directed RNA polymerase catalytic subunit (Influenza A virus) that is encoded in the genome of the H1N1 strain A/Puerto Rico/8/1934.


PA_I34A1 Polymerase acidic protein (sprot)

An influenza A virus polymerase acidic protein that is encoded in the genome of the H1N1 strain A/Puerto Rico/8/1934.


HEMA_I34A1 Hemagglutinin (sprot)

A hemagglutinin subtype H1 (Influenza A virus) that is encoded in the genome of the H1N1 strain A/Puerto Rico/8/1934.


NCAP_I34A1 Nucleoprotein (sprot)

A nucleoprotein (Influenza A virus) that is encoded in the genome of the H1N1 strain A/Puerto Rico/8/1934.


NRAM_I34A1 Neuraminidase (sprot)

A neuraminidase subtype N1 (Influenza A virus) that is encoded in the genome of the H1N1 strain A/Puerto Rico/8/1934.


M1_I34A1 Matrix protein 1 (sprot)

An influenzavirus matrix protein 1 that is encoded in the genome of the H1N1 strain A/Puerto Rico/8/1934.


NS1_I34A1 Non-structural protein 1 (sprot)

An influenzavirus non-structural protein 1 that is encoded in the genome of the H1N1 strain A/Puerto Rico/8/1934.


NEP_I34A1 Nuclear export protein (sprot)

An influenzavirus nuclear export protein that is encoded in the genome of the H1N1 strain A/Puerto Rico/8/1934.


M2_I34A1 Matrix protein 2 (sprot)

An influenzavirus matrix protein 2 that is encoded in the genome of the H1N1 strain A/Puerto Rico/8/1934.


PAX_I34A1 Protein PA-X (sprot)

An influenza A virus protein PA-X that is encoded in the genome of the H1N1 strain A/Puerto Rico/8/1934.


PB2_I33A0 Polymerase basic protein 2 (sprot)

A polymerase basic protein 2 (Influenza A virus) that is encoded in the genome of the H1N1 strain A/Wilson-Smith/1933.


RDRP_I33A0 RNA-directed RNA polymerase catalytic subunit (sprot)


HEMA_I33A0 Hemagglutinin (sprot)

A hemagglutinin subtype H1 (Influenza A virus) that is encoded in the genome of the H1N1 strain A/Wilson-Smith/1933.


NRAM_I33A0 Neuraminidase (sprot)

A neuraminidase subtype N1 (Influenza A virus) that is encoded in the genome of the H1N1 strain A/Wilson-Smith/1933.


M1_I33A0 Matrix protein 1 (sprot)

An influenzavirus matrix protein 1 that is encoded in the genome of the H1N1 strain A/Wilson-Smith/1933.


M2_I33A0 Matrix protein 2 (sprot)

An influenzavirus matrix protein 2 that is encoded in the genome of the H1N1 strain A/Wilson-Smith/1933.


PAX_I33A0 Protein PA-X (sprot)

An influenza A virus protein PA-X that is encoded in the genome of the H1N1 strain A/Wilson-Smith/1933.


PA_I33A0 Polymerase acidic protein (sprot)

An influenza A virus polymerase acidic protein that is encoded in the genome of the H1N1 strain A/Wilson-Smith/1933.


RNA polymerase activity

Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1); the synthesis of RNA from ribonucleotide triphosphates in the presence of a nucleic acid template.


protein import into nucleus

The directed movement of a protein from the cytoplasm to the nucleus.


NS1_I33A0 Non-structural protein 1 (sprot)

An influenzavirus non-structural protein 1 that is encoded in the genome of the H1N1 strain A/Wilson-Smith/1933.


NEP_I33A0 Nuclear export protein (sprot)

An influenzavirus nuclear export protein that is encoded in the genome of the H1N1 strain A/Wilson-Smith/1933.


NRAM_INBLE Neuraminidase (sprot)

A neuraminidase (Influenza B virus) that is encoded in the genome of strain B/Lee/1940.


NS1_INBLE Non-structural protein 1 (sprot)

An influenzavirus non-structural protein 1 that is encoded in the genome of Influenza B virus (strain B/Lee/1940).


NEP_INBLE Nuclear export protein (sprot)

An influenzavirus nuclear export protein that is encoded in the genome of Influenza B virus (strain B/Lee/1940).


RDRP_INBLE RNA-directed RNA polymerase catalytic subunit (sprot)


PA_INBLE Polymerase acidic protein (sprot)

A protein that is a translation product of the PA gene in Influenza B virus (strain B/Lee/1940).


PB2_INBLE Polymerase basic protein 2 (sprot)


HEMA_INCAA Hemagglutinin-esterase-fusion glycoprotein (sprot)


NS1_INCAA Non-structural protein 1 (sprot)

An influenzavirus non-structural protein 1 that is encoded in the genome of Influenza C virus (strain C/Ann Arbor/1/1950).


NEP_INCAA Nuclear export protein (sprot)

An influenzavirus nuclear export protein that is encoded in the genome of Influenza C virus (strain C/Ann Arbor/1/1950).


PA_INCAA Polymerase acidic protein (sprot)


RDRP_INCAA RNA-directed RNA polymerase catalytic subunit (sprot)


PB2_INCAA Polymerase basic protein 2 (sprot)


A0A0E4C2T1_9ORTO Hemagglutinin-esterase-fusion glycoprotein (trembl)


A0A0E4C2X2_9ORTO Polyprotein p42 (trembl)


A0A0E4G393_9ORTO RNA-directed RNA polymerase catalytic subunit (trembl)


A0A0E4G3H6_9ORTO Non-structural protein 1 (trembl)


A0A0D3R164_9RHAB RNA-directed RNA polymerase L (trembl)


A0A0N7IQX4_9RHAB Matrix protein (trembl)


126R_IIV3 Uncharacterized protein 126R (sprot)


124R_IIV3 Uncharacterized protein 124R (sprot)


VF184_IIV3 Putative helicase 121R (sprot)


VF466_IIV3 Uncharacterized protein 112R (sprot)


VF414_IIV3 Putative hydrolase 111R (sprot)


VF161_IIV3 Putative helicase 109L (sprot)


VF030_IIV3 Uncharacterized protein 106R (sprot)


VF355_IIV3 Putative CTD phosphatase-like protein 355R (sprot)


RNC_IIV3 Putative ribonuclease 3 (sprot)


VF347_IIV3 Putative FAD-linked sulfhydryl oxidase 096R (sprot)


095L_IIV3 Probable matrix metalloproteinase 095L (sprot)


RPB1_IIV3 Probable DNA-directed RNA polymerase II subunit RPB1 homolog (sprot)


VF075_IIV3 Uncharacterized protein 088R (sprot)


VF022_IIV3 Putative helicase 087L (sprot)


VF203_IIV3 Uncharacterized protein 085L (sprot)


VF232_IIV3 Putative ubiquitin thioesterase 232R (sprot)


080R_IIV3 Putative hydrolase 080R (sprot)


VF282_IIV3 Putative transcription factor 079L (sprot)


VF244_IIV3 Putative phosphoesterase 078R (sprot)


VF369_IIV3 Probable RAD2-like endonuclease 076L (sprot)


073R_IIV3 Uncharacterized protein 073R (sprot)


VF306_IIV3 Putative SWIB domain-containing protein 070L (sprot)


VF401_IIV3 High mobility group protein homolog 068R (sprot)


VF197_IIV3 Putative tyrosine phosphatase 067L (sprot)


VF357_IIV3 Transmembrane protein 066L (sprot)


RIR1_IIV3 Ribonucleoside-diphosphate reductase large subunit (sprot)


EX0N_IIV3 Putative exonuclease 059L (sprot)


VF349_IIV3 Putative transcription elongation factor S-II-like protein 055R (sprot)


VF205_IIV3 Putative DNA ligase 052L (sprot)


RIR2_IIV3 Probable ribonucleoside-diphosphate reductase small subunit 048L (sprot)


VF337_IIV3 Putative membrane protein 047R (sprot)


044L_IIV3 Putative serine/threonine-protein kinase 040L (sprot)


VF010_IIV3 Uncharacterized protein 043R (sprot)


037L_IIV3 Uncharacterized protein 037L (sprot)


VF077_IIV3 Putative zinc finger protein 034R (sprot)


VF307_IIV3 Uncharacterized protein 033L (sprot)


VF143_IIV3 Putative kinase protein 029R (sprot)


VF157_IIV3 Putative RING finger protein 027R (sprot)


VF224_IIV3 Probable cysteine proteinase 024R (sprot)


022L_IIV3 Transmembrane protein 022L (sprot)


VF193_IIV3 Putative apoptosis inhibitor 021L (sprot)


013L_IIV3 Uncharacterized protein IIV3-013L (sprot)


VF302_IIV3 Putative zinc finger protein 012R (sprot)


VF380_IIV3 Probable serine/threonine-protein kinase 010L (sprot)


RPB2_IIV3 Probable DNA-directed RNA polymerase II subunit RPB2 homolog (sprot)


VF118_IIV3 Putative myristoylated protein 006R (sprot)


VF067_IIV3 Uncharacterized protein 004R (sprot)


S0BE02_9VIRU Ribonucleoside-diphosphate reductase (trembl)


W8W1N3_9VIRU Nicotinamide mononucleotide transporter (trembl)


W8W1P2_9VIRU Putative tyrosine phosphatase (trembl)


W8W1P8_9VIRU Hydrolase, NUDIX family (trembl)


W8W1Q0_9VIRU Transmembrane protein (trembl)


W8W1Q3_9VIRU Papain-like proteinase (trembl)


W8W1Q4_9VIRU Uncharacterized protein (trembl)


W8W1R0_9VIRU Lipid membrane protein (trembl)


W8W1R4_9VIRU Putative tyrosine protein kinase (trembl)


W8W1R5_9VIRU Uncharacterized protein (trembl)


W8W1R9_9VIRU Putative transcription elongation factor TFIIS (trembl)


W8W1S7_9VIRU Uncharacterized protein (trembl)


W8W1S9_9VIRU Proliferating cell nuclear antigen (trembl)


W8W1T0_9VIRU 5'-3' Exoribonuclease 1 (trembl)


W8W1T3_9VIRU Transmembrane protein (trembl)


W8W1T8_9VIRU Serine/threonine-protein kinase pim-2-like (trembl)


W8W1U0_9VIRU Nudix hydrolase domain-containing protein (trembl)


W8W1U4_9VIRU Uncharacterized protein (trembl)


W8W1V3_9VIRU DNA ligase (NAD(+)) (trembl)


W8W1V4_9VIRU DNA-directed RNA polymerase (trembl)


W8W248_9VIRU Putative ubiquitin thioesteraseVirion core protein (trembl)


W8W249_9VIRU Matrix metalloproteinase-17-like (trembl)


W8W252_9VIRU RNA polymerase II subunit Rpb5b (trembl)


W8W254_9VIRU DNA-directed RNA polymerase subunit (trembl)


W8W259_9VIRU Uncharacterized protein (trembl)


W8W261_9VIRU Major capsid protein (trembl)


W8W262_9VIRU Uncharacterized protein (trembl)


W8W264_9VIRU Uncharacterized protein (trembl)


W8W266_9VIRU Haloacid dehalogenase-like hydrolases (trembl)


W8W268_9VIRU dihydrofolate reductase (trembl)


W8W269_9VIRU RING-type domain-containing protein (trembl)


W8W271_9VIRU Serine/threonine protein kinase (trembl)


W8W279_9VIRU DNA-directed RNA polymerase II subunit E (trembl)


W8W2H2_9VIRU Uncharacterized protein (trembl)


W8W2H4_9VIRU Sulfhydryl oxidase (trembl)


W8W2H5_9VIRU Uncharacterized protein (trembl)


W8W2H7_9VIRU Putative deoxynucleotide monophosphate kinase (trembl)


W8W2H9_9VIRU Flap endonuclease 1-A (trembl)


W8W2I0_9VIRU protein-serine/threonine phosphatase (trembl)


MAP kinase phosphatase activity

Catalysis of the reaction: a phosphorylated MAP kinase + H2O = a MAP kinase + phosphate.


W8W2J0_9VIRU Putative myristylated membrane protein (trembl)


W8W2J2_9VIRU ATP-dependent DNA helicase PIF1 (trembl)


W8W2J6_9VIRU Amylopullulanase like protein (trembl)


W8W2K1_9VIRU Uncharacterized protein (trembl)


W8W2K4_9VIRU DNA double-strand break repair rad50 ATPase-like (trembl)


DNA synthesis involved in DNA repair

Synthesis of DNA that proceeds from the broken 3' single-strand DNA end and uses the homologous intact duplex as the template.


W8W2V5_9VIRU D5 family helicase-primase (trembl)


W8W2V8_9VIRU DNA repair exonuclease SbcCD D subunit (trembl)


W8W2W1_9VIRU Uncharacterized protein (trembl)


W8W2W3_9VIRU High mobility group protein homolog (trembl)


W8W2W7_9VIRU ribonucleoside-diphosphate reductase (trembl)


W8W2X2_9VIRU Serine/threonine protein kinase (trembl)


W8W2X4_9VIRU Uncharacterized protein (trembl)


W8W2X6_9VIRU dUTP diphosphatase (trembl)


W8W2X8_9VIRU SWI/SNF2 family helicase (trembl)


W8W2Y2_9VIRU DNA binding/packing protein (trembl)


W8W2Y4_9VIRU DNA topoisomerase 2 (trembl)


W8W2Y5_9VIRU thymidylate synthase (trembl)


W8W2Y7_9VIRU C3H1-type domain-containing protein (trembl)


056R_IIV6 Uncharacterized protein 056R (sprot)


060L_IIV6 Uncharacterized protein 060L (sprot)


061R_IIV6 Uncharacterized protein 061R (sprot)


VF067_IIV6 Uncharacterized protein 067R (sprot)


VF075_IIV6 Uncharacterized protein 075L (sprot)


VF077_IIV6 Putative zinc finger protein 077L (sprot)


083L_IIV6 Uncharacterized protein 083L (sprot)


084L_IIV6 Uncharacterized protein 084L (sprot)


RIR1_IIV6 Ribonucleoside-diphosphate reductase large subunit (sprot)


095L_IIV6 Putative RING finger protein 095L (sprot)


PARP_IIV6 Putative poly [ADP-ribose] polymerase-like 100L (sprot)


107L_IIV6 Uncharacterized protein 107L (sprot)


113L_IIV6 Uncharacterized protein 113L (sprot)


VF118_IIV6 Putative myristoylated protein 118L (sprot)


121R_IIV6 Putative RING finger protein 121R (sprot)


123R_IIV6 Putative tyrosine phosphatase 123R (sprot)


132L_IIV6 Putative zinc finger protein 132L (sprot)


138R_IIV6 Uncharacterized protein 138R (sprot)


140L_IIV6 Uncharacterized protein 140L (sprot)


141R_IIV6 Uncharacterized protein 141R (sprot)


RNC_IIV6 Putative ribonuclease 3 (sprot)


VF143_IIV6 Putative kinase protein 143R (sprot)


VF157_IIV6 Putative RING finger protein 157L (sprot)


VF161_IIV6 Putative helicase 161L (sprot)


165R_IIV6 Putative metalloproteinase 165R (sprot)


169L_IIV6 Uncharacterized protein 169L (sprot)


VF170_IIV6 Uncharacterized protein 170L (sprot)


172L_IIV6 Putative helicase 172L (sprot)


175R_IIV6 Putative RING finger protein 175R (sprot)


RPB1_IIV6 Probable DNA-directed RNA polymerase II subunit RPB1 homolog (sprot)


VF179_IIV6 Uncharacterized protein 179R (sprot)


VF184_IIV6 Putative helicase 184R (sprot)


HMGH_IIV6 High mobility group protein homolog (sprot)


413R_IIV6 Putative RING finger protein 413R (sprot)


VF193_IIV6 Apoptosis inhibitor 193R (sprot)


VF466_IIV6 Uncharacterized protein 466R (sprot)


463L_IIV6 Probable lipid hydrolase 463L (sprot)


458R_IIV6 Putative myristoylated membrane protein 458R (sprot)


454R_IIV6 Putative DNA-directed RNA polymerase subunit 454R (sprot)


Toll signaling pathway

biolink:Pathway biolink:BiologicalProcess biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:OntologyClass biolink:Occurrent biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

The series of molecular signals initiated by an extracellular ligand binding to the receptor Toll on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.


438L_IIV6 Probable deoxyuridine 5'-triphosphate nucleotidohydrolase (sprot)


RPB2_IIV6 Probable DNA-directed RNA polymerase II subunit RPB2 homolog (sprot)


VF414_IIV6 Putative hydrolase 414L (sprot)


VF391_IIV6 Uncharacterized protein 391R (sprot)


389L_IIV6 Probable serine/threonine-protein kinase 389L (sprot)


VF380_IIV6 Probable serine/threonine-protein kinase 380R (sprot)


RIR2_IIV6 Probable ribonucleoside-diphosphate reductase small subunit 376L (sprot)


VF369_IIV6 Probable RAD2-like endonuclease 369L (sprot)


361L_IIV6 Probable cysteine proteinase 361L (sprot)


VF355_IIV6 Putative CTD phosphatase-like protein 355R (sprot)


VF349_IIV6 Putative transcription elongation factor S-II-like protein 349L (sprot)


VF347_IIV6 Putative FAD-linked sulfhydryl oxidase 347L (sprot)


343L_IIV6 Probable DNA-directed RNA polymerase subunit 343L (sprot)


340R_IIV6 DRBM domain-containing protein 340R (sprot)


VF337_IIV6 Putative membrane protein 337L (sprot)


332L_IIV6 Uncharacterized RING finger protein 332L (sprot)


325L_IIV6 Uncharacterized protein 325L (sprot)


VF307_IIV6 Uncharacterized protein 307L (sprot)


VF306_IIV6 Putative SWIB domain-containing protein 306R (sprot)


VF302_IIV6 Putative zinc finger protein 302L (sprot)


300R_IIV6 Transmembrane protein 300R (sprot)


VF295_IIV6 Uncharacterized protein 295L (sprot)


VF282_IIV6 Putative transcription factor 282R (sprot)


VF259_IIV6 Uncharacterized protein 259R (sprot)


KTHY_IIV6 Putative thymidylate kinase 251L (sprot)


VF244_IIV6 Putative phosphoesterase 244L (sprot)


235L_IIV6 Putative methyltransferase 235L (sprot)


234R_IIV6 Uncharacterized protein 234R (sprot)


VF232_IIV6 Putative ubiquitin thioesterase 232R (sprot)


227L_IIV6 Uncharacterized protein 227L (sprot)


VF224_IIV6 Probable cysteine proteinase 224L (sprot)


VF213_IIV6 Transmembrane protein 213R (sprot)


VF205_IIV6 Putative DNA ligase 205R (sprot)


VF203_IIV6 Uncharacterized protein 203L (sprot)


VF197_IIV6 Putative tyrosine phosphatase 197R (sprot)


135R_IIV6 Uncharacterized protein 135R (sprot)


065R_IIV6 Uncharacterized protein 065R (sprot)


049L_IIV6 Transmembrane protein 049L (sprot)


034R_IIV6 Uncharacterized protein 034R (sprot)


VF010_IIV6 Transmembrane protein 010R (sprot)


VF030_IIV6 Uncharacterized protein 030L (sprot)


VF022_IIV6 Putative helicase 022L (sprot)


EXON_IIV6 Putative exonuclease 012L (sprot)


TYSY_IIV6 Probable thymidylate synthase 225R (sprot)


A0A0D3R0Z4_9RHAB Uncharacterized protein (trembl)


A0A0D3R127_9RHAB Matrix protein (trembl)


A0A4P8D7T3_9VIRU Envelopment polyprotein (trembl)


A0A4V1DW07_9VIRU RNA-directed RNA polymerase L (trembl)


A0A142D6T1_9LUTE Putative fusion protein P1-P2 (trembl)


A0A142D6T2_9LUTE Peptidase S39 domain-containing protein (trembl)


A0A142D6T3_9LUTE Readthrough protein (trembl)


A0A142D6T4_9LUTE Putative coat protein P3 (trembl)


A0A142D6T5_9LUTE Movement protein (trembl)


A0A1U8YLV2_9TOMB Putative movement protein (trembl)


A0A1U8YMV9_9TOMB RNA-directed RNA polymerase (trembl)


Q49HN2_9MONO RNA-directed RNA polymerase L (trembl)


Q49HN3_9MONO Attachment glycoprotein (trembl)


Q49HN4_9MONO Transmembrane protein (trembl)


Q49HN5_9MONO Small hydrophobic protein (trembl)


Q49HN6_9MONO Fusion glycoprotein F0 (trembl)


VP1_POVJC Major capsid protein VP1 (sprot)


VP2_POVJC Minor capsid protein VP2 (sprot)


B0F1A8_9VIRU Non-structural protein NS-S (trembl)


E2EZP9_9VIRU Envelopment polyprotein (trembl)


E2EZQ0_9VIRU RNA-directed RNA polymerase L (trembl)


C7T4Z4_9VIRU Replicase-associated polyprotein (trembl)


Q9IR98_9TOMB Movement protein (P12) (trembl)


Q9IRA1_9TOMB RNA-directed RNA polymerase (trembl)


Q9IRA2_9TOMB RNA-directed RNA polymerase (trembl)


Q9JGJ9_9VIRU 64-kDa readthrough protein (Fragment) (trembl)


Q9JGK1_9VIRU 37-kDa movement protein (trembl)


Q9JGK2_9VIRU 59-kDa readthrough protein (Fragment) (trembl)


A0A8J9RCA8_9VIRU Nucleocapsid protein (trembl)


A0A8J9WH93_9VIRU RNA-directed RNA polymerase L (trembl)


A0A346G4C3_9TOMB RNA-dependent RNA polymerase (trembl)


A0A346G4C4_9TOMB RNA-directed RNA polymerase (trembl)


A0A346G4C6_9TOMB MP2 (Fragment) (trembl)


A0A346G4C7_9TOMB Capsid protein (trembl)


A0A173G8H1_9VIRU Triple gene block I (trembl)


A0A173G8H3_9VIRU Movement protein TGBp3 (trembl)


A0A173G8I1_9VIRU RNA silencing suppressor (trembl)


A0A173G8K3_9VIRU Movement protein TGB2 (trembl)


A0A1C9CUR7_9VIRU Capsid protein (trembl)


A0A0U1ZX52_9GEMI Transcriptional activator protein (trembl)


A0A0U1ZY85_9GEMI Replication-associated protein (trembl)


A0A0U2A153_9GEMI Replication enhancer (trembl)


A0A0U2A2S6_9GEMI Capsid protein (trembl)


B5A468_9GEMI Replication enhancer (trembl)


B5A469_9GEMI Transcriptional activator protein (trembl)


B5A470_9GEMI Replication-associated protein (trembl)


B6DXE6_9GEMI Replication enhancer (trembl)


B6DXE7_9GEMI Transcriptional activator protein (trembl)


B6DXE8_9GEMI Replication-associated protein (trembl)


VIF_JEMBR Virion infectivity factor (sprot)


A0A1L3KG14_9VIRU RNA-directed RNA polymerase (trembl)


A0A1L3KG50_9VIRU RNA-directed RNA polymerase (trembl)


Q70P86_9TOMB RNA-directed RNA polymerase (trembl)


A0A0D3R1D5_9RHAB Uncharacterized protein (trembl)


A0A0D3R257_9RHAB Matrix protein (trembl)


A0A0H4B2P0_9VIRU RNA-directed RNA polymerase L (trembl)


H6SW52_9ORTO RNA-directed RNA polymerase catalytic subunit (Fragment) (trembl)


A0A515L4K4_9VIRU RNA-directed RNA polymerase L (trembl)


A0A515L4L7_9VIRU Nucleocapsid protein (trembl)


A0A2I8B2J7_9GEMI Replication enhancer (trembl)


A0A2I8B2J9_9GEMI Capsid protein (trembl)


A0A2I8B2K0_9GEMI Replication-associated protein (trembl)


A0A2K8MNE1_9MONO RNA-directed RNA polymerase (trembl)


A0A2Z5WAC6_9VIRU Envelopment polyprotein (trembl)


A0A2Z5WAC9_9VIRU RNA-directed RNA polymerase L (trembl)


Q9INJ2_9REOV RNA-directed RNA polymerase (trembl)


A0A1B1X3Z6_9NIDO Putative ORF1a (trembl)


A0A1B1X3Z7_9NIDO Putative nucleocapsid (trembl)


A0A1B1X3Z9_9NIDO Putative membrane protein (trembl)


A0A1B1X401_9NIDO Replicase polyprotein 1ab (trembl)


A0A088MFP2_9VIRU RNA-directed RNA polymerase L (trembl)


A0A088MFQ0_9VIRU Envelopment polyprotein (trembl)


A0A088MFR5_9VIRU Non-structural protein NS-S (trembl)


A0A0Y0B411_9NIDO Putative nsp2F protein (trembl)


A0A0Y0BBM4_9NIDO ORF2a' protein (trembl)


A0A0Y0BQ57_9NIDO 1a replicase protein (trembl)


A0A0Y0BX48_9NIDO Replicase polyprotein 1ab (trembl)


A0A0F7KLP0_9VIRU ACH96205.1 dnaint/rec-like protein (trembl)


A0A0F7KLQ3_9VIRU ACH96237.1 pif-3-like protein (trembl)


A0A0F7KMR9_9VIRU ACH96171.1 GrBNV gp95-like protein (trembl)


A0A0F7KMX2_9VIRU ACH96202.1 Ac68-like protein (trembl)


A0A0F7KNK5_9VIRU ACH96177.1 GrBNV gp19-like protein (trembl)


A0A1S5VFX9_9VIRU Uncharacterized protein (trembl)


A0A1S5VFY0_9VIRU EGF-like domain-containing protein (trembl)


A0A1S5VFY1_9VIRU Putative protease (trembl)


A0A1S5VFY2_9VIRU Putative deoxynucleoside kinase protein (trembl)


A0A1S5VFY3_9VIRU Uncharacterized protein (trembl)


A0A1S5VFY5_9VIRU ACH96134.1 Ac81-like protein (trembl)


A0A1S5VFY6_9VIRU DNA polymerase (trembl)


A0A1S5VFY9_9VIRU ACH96132.1 trypsin-like serine protease-like protein (trembl)


A0A1S5VFZ0_9VIRU Uncharacterized protein (trembl)


A0A1S5VFZ2_9VIRU Putative serine protease (trembl)


A0A1S5VFZ4_9VIRU ACH96141.1 mitochondrial carrier protein-like protein (trembl)


A0A1S5VFZ5_9VIRU ACH96153.1 guanylate kinase-like protein (trembl)


A0A1S5VFZ7_9VIRU ACH96147.1 pif-2-like protein (trembl)


A0A1S5VG07_9VIRU ACH96160.1 vlf-1-like protein (trembl)


A0A1S5VG09_9VIRU ACH96163.1 19kda protein-like protein (trembl)


A0A1S5VG22_9VIRU ACH96187.1 patatin-like phospholipase-like protein (trembl)


A0A1S5VG24_9VIRU ribonucleoside-diphosphate reductase (trembl)


A0A1S5VG25_9VIRU ACH96194.1 lef-8-like protein (trembl)


A0A1S5VG33_9VIRU ACH96190.1 pif-1-like protein (trembl)


A0A1S5VG34_9VIRU ACH96191 GrBNV gp51-like protein (trembl)


A0A1S5VG41_9VIRU ACH96245.1 odv-e56-like protein (trembl)


A0A1S5VG47_9VIRU ACH96209.1 GrBNV gp59-like protein (trembl)