regulation of xanthophore differentiation

Any process that modulates the frequency, rate or extent of xanthophore differentiation.


negative regulation of blood vessel remodeling

biolink:BiologicalProcess biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:Occurrent biolink:OntologyClass biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

Any process that decreases the rate, frequency or extent of blood vessel remodeling, the reorganization or renovation of existing blood vessels.


mRNA splice site recognition

Selection of a splice site by components of the assembling spliceosome.


epidermis morphogenesis involved in nipple formation

The process in which the epidermis of the nipple sheath is uplifted to form an umbrella-like projection.


modulation by host of viral transcription

Any process in which a host organism modulates the frequency, rate or extent of viral transcription.


aldehyde dehydrogenase (NAD+) activity

biolink:MolecularActivity biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:Occurrent biolink:OntologyClass biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

Catalysis of the reaction: an aldehyde + NAD+ + H2O = an acid + NADH + H+.


naringenin-chalcone synthase activity

Catalysis of the reaction: 3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO2.


alpha-copaene metabolic process

The chemical reactions and pathways involving alpha-copaene.


hydrogen sulfide metabolic process

The chemical reactions and pathways involving hydrogen sulfide, H2S.


intracellular nitrogen homeostasis

A homeostatic process involved in the maintenance of a steady state level of nitrogen within a cell.


meiotic telophase II

The cell cycle phase which follows anaphase II of meiosis and during which the chromosomes arrive at the poles of the cell and the division of the cytoplasm starts.


cephamycin C metabolic process

The chemical reactions and pathways involving cephamycin C.


voltage-gated calcium channel activity involved in regulation of cytosolic calcium levels

Regulation of cytosolic calcium ion concentrations via the directed movement of calcium ions across the plasma-membrane into the cytosol via the action of a voltage-gated calcium ion channel.


exit from dormancy

The dormancy process that results in exit from dormancy. Dormancy (sometimes called a dormant state) is a suspension of most physiological activity and growth that can be reactivated.


methyl transfer-driven active transmembrane transporter activity

Primary active transport of a solute across a membrane driven by a methyl transfer reaction. Primary active transport is catalysis of the transport of a solute across a membrane, up the solute's concentration gradient, by binding the solute and undergoing a series of conformational changes. Transport works equally well in either direction and is driven by a primary energy source.


respiratory chain complex III assembly

The aggregation, arrangement and bonding together of a set of components to form the cytochrome bc(1) complex, a transmembrane lipoprotein complex that it catalyzes the reduction of cytochrome c by accepting reducing equivalents from Coenzyme Q, by the aggregation, arrangement and bonding together of its constituents.


regulation of paraxial mesodermal cell fate determination

Any process that modulates the frequency, rate or extent of paraxial mesoderm cell fate determination.


regulation of premature acrosome loss

Any process that modulates the rate, frequency or extent of the discharge, by sperm, of a single, anterior secretory granule before the sperm reaches to the zona pellucida of the oocyte. The process begins with the fusion of the outer acrosomal membrane with the sperm plasma membrane and ends with the exocytosis of the acrosomal contents.


central nervous system neuron axonogenesis

Generation of a long process from a neuron whose cell body resides in the central nervous system. The process carries efferent (outgoing) action potentials from the cell body towards target cells.


negative regulation of transmembrane transport

Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a solute from one side of a membrane to the other.


negative regulation of monoatomic anion transport

Any process that stops, prevents or reduces the frequency, rate or extent of anion transport.


positive regulation of L-proline import across plasma membrane

Any process that activates or increases the frequency, rate or extent of L-proline import across plasma membrane.


cuprous ion binding

Binding to a cuprous ion, copper(1+).


negative regulation of nuclear migration during mitotic telophase

Any process that stops, prevents or reduces the frequency, rate or extent of nuclear migration during mitotic telophase.


regulation of octopamine signaling pathway involved in response to food

Any process that modulates the frequency, rate or extent of octopamine signaling pathway involved in response to food.


Catalysis of the transfer of an arachidonoyl (systematic name, (5Z,8Z,11Z,14Z)-eicosatetraenoyl) group to a sulfur atom on the cysteine of a protein molecule, in the reaction: in the reaction: (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + L-cysteinyl-[protein] = CoA + S-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-L-cysteinyl-[protein].


helvolic acid metabolic process

The chemical reactions and pathways involving helvolic acid.


envenomation resulting in negative regulation of sensory perception of pain in another organism

A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the inhibition of the sensory perception of pain in the bitten organism.


resolvin biosynthetic process

The chemical reactions and pathways resulting in the formation of resolvins, di- or trihydroxy fatty acids derived from omega-3 polyunsaturated fatty acids, specifically icosapentaenoic acid, docosahexaenoic acid and docosapentaenoic acid.


positive regulation of long-chain fatty acid import across plasma membrane

Any process that increases the rate, frequency or extent of plasma membrane long-chain fatty acid transport. Plasma membrane long-chain fatty acid transport is the directed movement of long-chain fatty acids across the plasma membrane. A long-chain fatty acid is a fatty acid with a chain length between C13 and C22.


positive regulation of hindgut contraction

Any process that increases the frequency, rate or extent of muscle contraction of the hindgut, the posterior part of the alimentary canal, including the rectum, and the large intestine.


20-aldehyde-leukotriene B4 20-monooxygenase activity

Catalysis of the reaction: 20-oxo-leukotriene B4 + O2 + reduced [NADPH-hemoprotein reductase] = 20-carboxy-leukotriene B4 + 2 H+ + H2O + oxidized [NADPH-hemoprotein reductase].


peptide modification

The covalent alteration of one or more amino acid residues within a peptide, resulting in a change in the properties of that peptide.


aortic valve formation

The developmental process pertaining to the initial formation of the aortic valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable.


detection of hypoxia

The series of events in which a stimulus indicating lowered oxygen tension is received by a cell and converted into a molecular signal. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.


nitrite reductase (NO-forming) activity

Catalysis of the reaction: nitric oxide + H2O + ferricytochrome c = nitrite + ferrocytochrome c + 2 H+.


comma-shaped body morphogenesis

The process in which the comma-shaped body is generated and organized. The comma-shaped body is the precursor structure to the S-shaped body that contributes to the morphogenesis of the nephron.


Catalysis of the reaction: a 10-formyltetrahydrofolate-4a-carbinolamine = H2O + a 10-formyldihydrofolate.


cell-cell adhesion involved in neural tube closure

The attachment of one cell to another cell along the edges of two epithelial folds, giving rise to the lumen of the neural tube.


maintenance of vegetative meristem identity

The process in which an organism retains a population of vegetative meristem cells, preventing the commitment of all stem cell progeny to a differentiated cell fate.


glycolytic fermentation to butanediol

The anaerobic chemical reactions and pathways resulting in the breakdown of glucose into butanediol; effected by some members of the Enterobacteriaceae, e.g. Enterobacter, Erwinia, Klebsiella, and Serratia.


G2 phase

The cell cycle 'gap' phase which is the interval between the completion of DNA synthesis and the beginning of DNA segregation (usually by mitosis or meiosis).


protein polyglutamylation

The addition of one or more alpha-linked glutamyl units to the gamma carboxyl group of peptidyl-glutamic acid.


myeloid cell homeostasis

The process of regulating the proliferation and elimination of myeloid cells such that the total number of myeloid cells within a whole or part of an organism is stable over time in the absence of an outside stimulus.


biolink:Pathway biolink:BiologicalProcess biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:OntologyClass biolink:Occurrent biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

The series of molecular signals initiated by interleukin-19 binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.


growth plate cartilage chondrocyte development

The progression of a growth plate cartilage chondrocyte over time from after its fate commitment to the mature cell.


visceral peritoneum development

The process whose specific outcome is the progression of a visceral peritoneum over time, from its formation to the mature structure.


membrane raft organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of membrane rafts, small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes.


detection of cAMP

The series of events in which a cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate) stimulus is received by a cell and converted into a molecular signal; cAMP is the nucleotide cyclic AMP.


histone H3R17 arginine deiminase activity

Catalysis of the reaction: H2O + histone H3 L-arginyl (position 17)= histone H3 L-citrullyl (position 17) + NH4+, resulting in histone H3 citrullination at position 17.


L-fucose catabolic process

The chemical reactions and pathways resulting in the breakdown of L-fucose (6-deoxy-Lgalactose).


phosphatidylglycerol binding

Binding to phosphatidylglycerol.


muscle cell chemotaxis toward tendon cell

The directed movement of a muscle cell towards a tendon cell in response to an external stimulus. Tendon cells, for example, produce positive guidance cues that attract muscle cells.


Catalysis of the reaction: L-histidyl-[protein] + S-adenosyl-L-methionine = N(pros)-methyl-L-histidyl-[protein] + S-adenosyl-L-homocysteine.


O6-methyl-dGTP hydrolase activity

Catalysis of the reaction O6-methyl-dGTP + H2O = O6-methyl-dGMP + diphosphate + H+.


The series of molecular signals initiated by interleukin-8 binding to its receptor on the surface of a cell, and ending with the regulation of a downstream cellular process, e.g. transcription.


sporocarp development involved in sexual reproduction

The process whose specific outcome is the progression of a fruiting body organ over time, from its formation to the mature structure. The fruiting body is a spore bearing structure. In fungi, the sporocarp (also known as fruiting body) is a multicellular structure on which spore-producing structures, such as basidia or asci, are borne. The fruiting body is part of the sexual phase of a fungal life cycle, with the rest of the life cycle being characterized by vegetative mycelial growth. The sporocarp of a basidiomycete is known as a basidiocarp, while the fruiting body of an ascomycete is known as an ascocarp. A significant range of different shapes and morphologies is found in both basidiocarps and ascocarps; these features play an important role in the identification and taxonomy of fungi.


regulation of defecation

Any process that modulates the frequency, rate or extent of defecation.


dGMP biosynthetic process

The chemical reactions and pathways resulting in the formation of dGMP, deoxyguanosine monophosphate (2'-deoxyguanosine 5'-phosphate).


regulation of chloride transport

Any process that modulates the frequency, rate or extent of chloride transport.


positive regulation of eosinophil differentiation

Any process that activates or increases the frequency, rate or extent of eosinophil differentiation.


termination of RNA polymerase II transcription, exosome-dependent

The process in which transcription of nonpolyadenylated RNA polymerase II transcripts is terminated; coupled to the maturation of the RNA 3'-end.


Catalysis of the reaction: S-adenosyl-L-methionine + guanine(37) in tRNA = N(1)-methylguanine(37) in tRNA + S-adenosyl-L-homocysteine.


intracellular sequestering of copper ion

The process of binding or confining copper ions in an intracellular area such that they are separated from other components of a biological system.


cell-cell signaling involved in pronephros development

Any process that mediates the transfer of information from one cell to another and contributes to the progression of the pronephros over time, from its formation to the mature organ.


regulation of cell fate specification

Any process that mediates the adoption of a specific fate by a cell.


regulation of membrane permeability

Any process that modulates the frequency, rate or extent of the passage or uptake of molecules by a membrane.


Schwann cell proliferation

The multiplication or reproduction of Schwann cells, resulting in the expansion of their population. Schwann cells are a type of glial cell in the peripheral nervous system.


regulation of cellobiose catabolic process

Any process that modulates the frequency, rate or extent of cellobiose catabolic process.


tagaturonate reductase activity

Catalysis of the reaction: D-altronate + NAD+ = D-tagaturonate + H+ + NADH.


Catalysis of the reaction: 1,1-dichloro-2,2-bis(4-chlorophenyl)ethane = HCl + 1-chloro-2,2-bis(4-chlorophenyl)ethene. 1,1-dichloro-2,2-bis(4-chlorophenyl)ethane is also known as DDD; 1-chloro-2,2-bis(4-chlorophenyl)ethene is also known as DDMU.


11-cis-retinal 3,4-desaturase activity

Catalysis of the reaction: 11-cis-retinal + 2 H+ + O2 + 2 reduced [adrenodoxin] = 11-cis-3,4-didehydro-retinal + 2 H2O + 2 oxidized [adrenodoxin].


stomatal complex patterning

The regionalization process of establishing the non-random spatial arrangement of stomatal complex on the surface of a leaf. The stomatal complex is the stomatal guard cells and their associated epidermal cells.


n-octane metabolic process

The chemical reactions and pathways involving n-octane, the 8 carbon straight chain alkane used in organic syntheses, calibrations, and azeotropic distillations. It is a common component of gasoline and other petroleum products and the engine fuel antiknocking properties of an isomer of n-octane are used as a comparative standard in the Octane Rating System.


peptidoglycan binding

Interacting selectively and non-covalently, in a non-covalent manner, with peptidoglycan, any of a class of glycoconjugates found in bacterial cell walls.


tRNA folding

The process of assisting in the folding of tRNAs into the correct tertiary structure.


lncRNA binding

Binding to a long noncoding RNA (lncRNA).


astrocyte cell migration

The orderly movement of an astrocyte, a class of large neuroglial (macroglial) cells in the central nervous system, the largest and most numerous neuroglial cells in the brain and spinal cord.


cellular response to stem cell factor stimulus

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stem cell factor (SCF) stimulus.


D-malate dehydrogenase (decarboxylating) activity

Catalysis of the reaction: (R)-malate + NAD+ = CO2 + NADH + pyruvate.


negative regulation of cell migration

Any process that stops, prevents, or reduces the frequency, rate or extent of cell migration.


calcitonin receptor activity

Combining with calcitonin and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.


regulation of angiotensin levels in blood

The process that modulates the level of any of the various angiotensinogen proteolytic products in the blood. This occurs by the proteolytic cleavage of angiotensinogen, and its proteolytic products, to create a variety of active peptide hormones, such as angiotensin I and angiotensin II, as well as through the removal of these peptides from the circulation.


cardiac ventricle formation

The developmental process pertaining to the initial formation of a cardiac ventricle from unspecified parts. A cardiac ventricle receives blood from a cardiac atrium and pumps it out of the heart.


tetralin ring-hydroxylating dioxygenase activity

Catalysis of the reaction: tetralin + O2 + NADH + H+ = cis-1,2-dihydroxy-1,2,5,6,7,8-hexahydronaphthalene + NAD+.


intracellular ligand-gated monoatomic ion channel activity

Enables the transmembrane transfer of an ion by a channel that opens when a specific intracellular ligand has been bound by the channel complex or one of its constituent parts.


mitochondrial tRNA methylation

The posttranscriptional addition of methyl groups to specific residues in a mitochondrial tRNA molecule.


regulation of animal organ formation

Any process that modulates the rate, frequency or extent of animal organ formation. Organ formation is the process pertaining to the initial formation of an organ from unspecified parts. The process begins with the specific processes that contribute to the appearance of the discrete structure, such as inductive events, and ends when the structural rudiment of the organ is recognizable, such as a condensation of mesenchymal cells into the organ rudiment.


cellular response to fibroblast growth factor stimulus

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an fibroblast growth factor stimulus.


modulation of spore encystment on host

Any process that modulates the frequency, rate or extent of spore encystment on host. The host is defined as the larger of the organisms involved in a symbiotic interaction.


regulation of heart contraction

Any process that modulates the frequency, rate or extent of heart contraction. Heart contraction is the process in which the heart decreases in volume in a characteristic way to propel blood through the body.


Catalysis of the reaction: UDP-glucose + ecdysteroid = UDP + glucosyl-ecdysteroid.


secondary active oligopeptide transmembrane transporter activity

Enables the transfer of an oligopeptide or oligopeptides from one side of a membrane to the other, up the solute's concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction.


Catalysis of the reaction: 4-aminobenzoate + UDP-glucose = p-aminobenzoate-beta-D-glucopyranosyl ester + UDP.


deoxyribonucleoside metabolic process

The chemical reactions and pathways involving any one of a family of organic molecules consisting of a purine or pyrimidine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside).


flavonol metabolic process

The chemical reactions and pathways involving flavonols, a member of a class of vascular pigments formed by consecutive oxidative processes from the flavonoid intermediates flavanones and dihydroflavonols. Flavonols are the most widespread of the flavonoids and have a wide array of physiological activities.


negative regulation of striated muscle cell apoptotic process

Any process that decreases the rate or extent of striated muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a striated muscle cell and result in its death.


nitrobenzene catabolic process

The chemical reactions and pathways resulting in the breakdown of nitrobenzene.


organometal metabolic process

The chemical reactions and pathways involving organometals, any metal-containing organic compound, especially one in which the metal atom is linked directly to one of more carbon atoms.


N-succinyltransferase activity

Catalysis of the transfer of a succinyl group to a nitrogen atom on the acceptor molecule.


hypochlorous acid catabolic process

The chemical reactions and pathways resulting in the breakdown of hypochlorous acid.


very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase activity

Catalysis of the reaction: a very-long-chain (3R)-3-hydroxyacyl-CoA = H2O + a very-long-chain (2E)-enoyl-CoA.


tRNA exon ligation

An RNA exon ligation process that rejoins two exons of a pre-tRNA which has had the intron removed.


pronephric distal tubule development

The process whose specific outcome is the progression of the pronephric distal tubule over time, from its formation to the mature structure. A pronephric nephron tubule is an epithelial tube that is part of the pronephros.


Catalysis of the reaction: NAD + D-glucopyranose 6-phosphate = NADH + H+ + 3-dehydro-D-glucose 6-phosphate.


Catalysis of the reaction: 3-oxopropanoate + NAD(P)+ + H2O = malonate + NAD(P)H + H+.


steviolbioside glucosyltransferase activity (rebaudioside B forming)

Catalysis of the reaction: steviolbioside + UDP-alpha-D-glucose = rebaudioside B + UDP + H+.


positive regulation of T cell costimulation

Any process that activates or increases the frequency, rate or extent of T cell costimulation.


commissural neuron axon guidance

The process in which the migration of an axon growth cone of a commissural neuron is directed to its target in the brain in response to a combination of attractive and repulsive cues.


response to anticonvulsant

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an anticonvulsant stimulus, a drug used to prevent seizures or reduce their severity.


negative regulation of vascular endothelial cell proliferation

Any process that stops, prevents or reduces the frequency, rate or extent of vascular endothelial cell proliferation.


regulation of ATP-dependent activity

Any process that modulates the rate of an ATP-dependent activity.


Catalysis of the transfer, in a beta 1,3 linkage, of D-glucuronic acid (GlcUA) from UDP-GlcUA to asioloorosomucoid.


1,2-rhamnosyltransferase activity

Catalysis of the reaction: isoorientin + an L-rhamonsylated rhamnosyl acceptor = isoorientin 2'-O-rhamnoside + a non rhamnosylated rhamnosyl acceptor.


peptidyl-serine autophosphorylation

The phosphorylation by a protein of one or more of its own serine amino acid residues, or a serine residue on an identical protein.


The series of molecular signals initiated by interleukin-22 binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.


beta-ribofuranosylaminobenzene 5'-phosphate synthase activity

Catalysis of the reaction: 4-aminobenzoate + 5-phospho-alpha-D-ribose 1-diphosphate = 4-(beta-D-ribofuranosyl)aminobenzene 5'-phosphate + CO2 + diphosphate.


negative regulation of complement activation, alternative pathway

Any process that stops, prevents, or reduces the frequency, rate or extent of complement activation by the alternative pathway.


ecdysone-mediated polytene chromosome puffing

The decondensing (loosening) and swelling of the chromosomal sites of hormone-responsive genes on polytene chromosomes in response to increased production of the steroid hormone 20-hydroxyecdysone (ecdysone) in Drosophila larvae approaching pupation.


cell morphogenesis involved in semicircular canal fusion

The change in form (cell shape and size) that occurs when a semicircular canal epithelial cell acquires the structural features that allow it to contribute to the process of semicircular canal fusion.


AV node cell to bundle of His cell communication by electrical coupling

The process that mediates signaling interactions between an AV node cardiomyocyte and a bundle of His cardiac muscle cell by transfer of current between their adjacent cytoplasms via intercellular protein channels.


viral scaffold assembly and maintenance

The assembly and maintenance of the viral scaffold around which the viral capsid is constructed.


Catalysis of the reaction: 2-(S)-hydroxypropyl-coenzyme M + NAD+ = 2-oxopropyl-coenzyme M + H+ + NADH.


microtubule plus end polymerase

Catalysis of the transfer of tubulin dimers to the plus end of a microtubule. The reaction is reversable depending on the availability of dimers.


primary amino compound catabolic process

The chemical reactions and pathways resulting in the breakdown of primary amino compound.


zygospore formation

The process in which zygospores are formed. Zygospores are characteristic of the zygomycete fungi (phylum Zygomycota) thick-walled and darkly colored, and usually heavily ornamented as well, with many spines or ridges. It is formed between two specialized organs called suspensors, which are themselves usually heavily ornamented, one from each mating partner. The zygospore forms between them and then breaks away.


betaine aldehyde catabolic process

The chemical reactions and pathways resulting in the breakdown of betaine aldehyde.


methylenetetrahydrofolate reductase (NAD(P)H) activity

Catalysis of the reaction: 5-methyltetrahydrofolate + NAD(P)+ = 5,10-methylenetetrahydrofolate + NAD(P)H + H+.


homogentisate metabolic process

The chemical reactions and pathways involving homogentisate.


gated channel activity

Enables the transmembrane transfer of a solute by a channel that opens in response to a specific stimulus.


motogenic signaling involved in interneuron migration from the subpallium to the cortex

The creation and reception of signals that result in the directional movement of interneuron precursors from the subpallium to the cortex.


heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules

The attachment of an adhesion molecule in one cell to a nonidentical adhesion molecule in an adjacent cell.


Catalysis of the reaction: 9,10-dihydroxybenzo(a)pyrene + O2 = cis-4-(8-hydroxypyren-7-yl)-2-oxobut-3-enoate.


positive regulation of ectoderm development

Any process that activates or increases the frequency, rate or extent of ectoderm development.


response to clozapine

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a clozapine stimulus.


contractile vacuole tethering involved in discharge

The initial, indirect interaction between a contractile vacuole membrane and a site of discharge in the plasma membrane. This interaction is mediated by tethering factors (or complexes), which interact with both membranes. Interaction can occur via direct binding to membrane phospholipids or membrane proteins, or via binding to vesicle coat proteins. This process is distinct from and prior to docking and fusion.


L-seryl-tRNA(Sec) selenium transferase activity

Catalysis of the reaction: L-seryl-tRNA(Sec) + selenophosphate = L-selenocysteinyl-tRNA(Sec) + H2O + phosphate.


positive regulation of intestinal lipid absorption

Any process that activates or increases the frequency, rate or extent of intestinal lipid absorption.


cardiac neuron development

The process whose specific outcome is the progression of a cardiac neuron over time, from its formation to the mature state.


embryonic limb morphogenesis

The process, occurring in the embryo, by which the anatomical structures of the limb are generated and organized. A limb is an appendage of an animal used for locomotion or grasping.


(R)-pantolactone dehydrogenase (flavin) activity

Catalysis of the reaction: (R)-pantolactone + A = 2-dehydropantolactone + AH(2).


histone H3S28 kinase activity

Catalysis of the reaction: histone H3-serine (position 28) + ATP = histone H3-phosphoserine (position 28) + ADP. This reaction is the addition of a phosphate group to the serine residue at position 28 of histone H3.


pseudopodium retraction

The myosin-based contraction and retraction of a pseudopodium.


skeletal muscle cell proliferation

The multiplication or reproduction of skeletal muscle cells, resulting in the expansion of a cell population.


ferricrocin metabolic process

The chemical reactions and pathways involving ferricrocin, a cyclic hexapeptide siderophore with the structure Gly-Ser-Gly-(N5-acetyl-N5-hydroxyornithine)3.


chloroplast protein-transporting ATPase activity

Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O = ADP + phosphate; drives the transport of proteins into the chloroplast stroma.


chloroplast mRNA processing

Steps involved in processing precursor RNAs arising from transcription of operons in the chloroplast genome into mature mRNAs.


renal system process involved in regulation of systemic arterial blood pressure

Renal process that modulates the force with which blood travels through the circulatory system. The process is controlled by a balance of processes that increase pressure and decrease pressure.


regulation of antigen processing and presentation of peptide antigen

Any process that modulates the frequency, rate, or extent of antigen processing and presentation of peptide antigen.


isopenicillin-N epimerase activity

Catalysis of the reaction: isopenicillin N = penicillin N.


The chemical reactions and pathways resulting in the formation of sphinganine-1-phosphate, the phosphorylated derivative of D-erythro-2-amino-1,3-octadecanediol.


2-hydroxy-ATP hydrolase activity

Catalysis of the reaction: 2-hydroxy-ATP + H2O = 2-hydroxy-AMP + H+ + diphosphate.


protein myristoylation

The covalent attachment of a myristoyl group to a protein.


establishment of RNA localization to telomere

The directed movement of RNA to a specific location in the telomeric region of a chromosome.


cyanidin 3-O-glucoside 6''-O-malonyltransferase activity

Catalysis of the reaction: cyanidin 3-O-beta-D-glucoside betaine + malonyl-CoA <=> cyanidin 3-O-(6-O-malonyl-beta-D-glucoside) + coenzyme A.


positive regulation of macrophage migration inhibitory factor signaling pathway

Any process that activates or increases the frequency, rate or extent of macrophage migration inhibitory factor signaling pathway.


optical nerve axon regeneration

The regrowth of axons of the optical nerve following their loss or damage.


tight junction disassembly

The disaggregation of an tight junction into its constituent components.


negative regulation of B cell receptor signaling pathway

Any process that stops, prevents, or reduces the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B cell.


organelle inheritance

The partitioning of organelles between daughter cells at cell division.


alpha-glucoside transmembrane transporter activity

Enables the transfer of alpha-glucosides from one side of a membrane to the other. Alpha-glucosides are glycosides in which the sugar group is a glucose residue, and the anomeric carbon of the bond is in an alpha configuration.


positive regulation of border follicle cell delamination

Any process that increases the frequency, rate or extent of border cell delamination.


(1->3)-beta-D-glucan immune receptor activity

Combining with (1->3)-beta-D-glucans to initiate an innate immune response.


(S)-reticuline biosynthetic process

The chemical reactions and pathways resulting in the formation of (S)-reticuline.


ADP biosynthetic process

The chemical reactions and pathways resulting in the formation of ADP, adenosine 5'-diphosphate.


regulation of BMP signaling pathway

Any process that modulates the frequency, rate or extent of the activity of any BMP receptor signaling pathway.


di-trans, poly-cis-undecaprenol kinase activity

Catalysis of the reaction: di-trans, octa-cis-undecaprenol + ATP = di-trans,octa-cis-undecaprenyl phosphate + ADP + H+.


dolichol-linked oligosaccharide biosynthetic process

The chemical reactions and pathways resulting in the formation of dolichol-linked oligosaccharide, usually by a stepwise addition of glycosyl chains to endoplasmic reticulum membrane-bound dolichol-P.


cell gliding

Cell motility that results in the smooth movement of a cell along a solid surface.


positive regulation of innate immunity memory response

Any process that activates or increases the frequency, rate or extent of innate immunity memory response.


regulation of response to salt stress

Any process that modulates the frequency, rate or extent of response to salt stress.


monoterpene catabolic process

The chemical reactions and pathways resulting in the breakdown of monoterpenes, terpenes with a C10 structure.


Catalysis of the reaction: naphthyl-2-methyl-succinate + succinyl-CoA = naphthyl-2-methyl-succinyl-CoA + succinate.


negative regulation of establishment of blood-brain barrier

Any process that decreases the rate, frequency or extent of the establishment of the blood-brain barrier, a selectively permeable structural and functional barrier that exists between the capillaries and the brain.


regulation of catabolic process

Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of substances.


regulation of toll-like receptor 12 signaling pathway

Any process that modulates the frequency, rate, or extent of toll-like receptor 12 signaling pathway.


neural plate morphogenesis

The process in which the anatomical structures of the neural plate are generated and organized. The neural plate is a specialized region of columnar epithelial cells in the dorsal ectoderm that will give rise to nervous system tissue.


response to manganese starvation

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of manganese.


mammary gland lobule development

The progression of the mammary gland lobule over time, from its formation to the mature structure. A mammary gland lobule is a small rounded projection of the mammary gland.


Catalysis of the reaction: Se-Methyl-L-selenocysteine + H2O => pyruvic acid + NH3 + Methaneselenol.


specification of pronephric distal tubule identity

The process in which the distal tubule of the pronephric nephron acquires its identity.


Catalysis of the reaction: NAD+ + 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate = NADH + CO2 + catechol.


positive regulation of brown fat cell proliferation

Any process that activates or increases the rate or extent of brown fat cell proliferation.


cerebellar Golgi cell differentiation

The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature cerebellar Golgi cell. Differentiation includes the processes involved in commitment of a neuroblast to a Golgi cell fate. A cerebellar Golgi cell is an inhibitory GABAergic interneuron found in the cerebellar cortex.


gamma-tubulin complex binding

Binding to a gamma-tubulin complex.


cellular response to arsenite ion

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an arsenite ion stimulus.


cis assembly of pre-catalytic spliceosome

Assembly of a spliceosomal complex containing the intact pre-mRNA and all of the spliceosomal snRNPs. This occurs when the tri-snRNP associates with the pre-mRNA and associated snRNPs in an ATP-dependent manner.


negative regulation of PERK-mediated unfolded protein response

Any process that stops, prevents or reduces the frequency, rate or extent of the PERK-mediated unfolded protein response.


DNA-binding transcription repressor activity, RNA polymerase III-specific

A DNA-binding transcription factor activity that represses or decreases the transcription of specific genes sets transcribed by RNA polymerase III.


inhibition of non-skeletal tissue mineralization

A homeostatic process involved in the maintenance of non-mineral tissue, by preventing mineralization of non-skeletal tissue.


beta-glucoside metabolic process

The chemical reactions and pathways involving beta-glucoside.


negative regulation of oligodendrocyte differentiation

Any process that stops, prevents, or reduces the frequency, rate or extent of oligodendrocyte differentiation.


negative regulation of pharyngeal pumping

Any process that stops, prevents or reduces the frequency, rate or extent of pharyngeal pumping.


guanosine biosynthetic process

The chemical reactions and pathways resulting in the formation of guanine, guanine riboside, a nucleoside with a wide species distribution.


response to camptothecin

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a camptothecin stimulus.


phloem development

The formation of the principal food-conducting tissue of a vascular plant.


cardiac left atrium morphogenesis

The process in which the left cardiac atrium is generated and organized.


GTPase-dependent fusogenic activity

A GTPase activity that mediates the joining two lipid bilayers to form a single membrane.


proline binding

Binding to proline.


cell-matrix adhesion involved in ameboidal cell migration

The binding of a cell to the extracellular matrix that contributes to the directed movement of an ameboid cell.


negative regulation of glucomannan catabolic process

Any process that stops, prevents or reduces the frequency, rate or extent of glucomannan catabolic process.


fungal-type cell wall chitin biosynthetic process

The chemical reactions and pathways resulting in the formation of cell wall chitin, a linear polysaccharide consisting of P-1,4-linked N-acetyl-D-glucosamine residues, found in the walls of fungal cells.


DNA alkylation

The addition of alkyl groups to many positions on all four bases of DNA. Alkylating agents can also modify the bases of incoming nucleotides in the course of DNA synthesis.


reactive nitrogen species metabolic process

The chemical reactions and pathways involving a reactive nitrogen species.


positive regulation of type 2 immune response

Any process that activates or increases the frequency, rate, or extent of a type 2 immune response.


Catalysis of the reaction: S-adenosyl-L-methionine + 6-O-methylnorlaudanosoline = S-adenosyl-L-homocysteine + nororientaline.


chemoattraction of serotonergic neuron axon

The process in which a serotonergic neuron growth cone is directed to a specific target site in response to an attractive chemical signal.


mitochondrion distribution

Any process that establishes the spatial arrangement of mitochondria between and within cells.


laminaribiose phosphorylase activity

Catalysis of the reaction: 3-beta-D-glucosyl-D-glucose + phosphate = D-glucose + alpha-D-glucose 1-phosphate.


autophagosome membrane docking

The initial attachment of an autophagosome membrane to a target membrane, mediated by proteins protruding from the membrane of the vesicle and the target membrane. Docking requires only that the two membranes come close enough for these proteins to interact and adhere.


pentose catabolic process to ethanol

The anaerobic chemical reactions and pathways resulting in the breakdown of a pentose, any monosaccharide with a chain of five carbons, where one of the resulting products is ethanol.


long-term strengthening of neuromuscular junction

Any process that results in an increase in the efficacy of transmission at a neuromuscular synapse.


microtubule anchoring at centrosome

Any process in which a microtubule is maintained in a specific location in a cell by attachment to a centrosome.


inductive cell-cell signaling between paraxial mesoderm and motor neuron precursors

Short range signaling between cells of the paraxial mesoderm and motor neuron precursors in the spinal cord that specifies the fate of the motor column neuron precursors along the anterior-posterior axis.


nucleoside-specific channel forming porin activity

Enables the energy independent passage of nucleoside, sized less than 1000 Da, across a membrane. The transmembrane portions of porins consist exclusively of beta-strands which form a beta-barrel. They are found in the outer membranes of Gram-negative bacteria, mitochondria, plastids and possibly acid-fast Gram-positive bacteria.


regulation of inflorescence meristem growth

Any process involved in maintaining the size and shape of an inflorescence meristem.


negative regulation of cardiac muscle fiber development

Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle fiber development.


cellular response to plumbagin

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a plumbagin stimulus.


positive regulation of platelet activation

Any process that increases the rate or frequency of platelet activation. Platelet activation is a series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue.


maturation of SSU-rRNA from tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, 2S rRNA, LSU-rRNA)

Any process involved in the maturation of a precursor Small SubUnit (SSU) ribosomal RNA (rRNA) molecule into a mature SSU-rRNA molecule from the pre-rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, 5.8 S rRNA, 2S rRNA, and Large Subunit (LSU) in that order from 5' to 3' along the primary transcript.


Catalysis of the reaction: norspermine + oxygen + H2O = norspermidine + 3-aminopropanal + hydrogen peroxide.


positive regulation of mesenchymal cell proliferation involved in ureter development

Any process that activates or increases the frequency, rate or extent of mesenchymal cell proliferation involved in ureter development.


regulation of translational fidelity

Any process that modulates the ability of the translational apparatus to interpret the genetic code.


negative regulation of systemic arterial blood pressure

The process that reduces the force with which blood travels through the systemic arterial circulatory system.


maintenance of floral organ identity

The process in which the identity of a floral organ is maintained. Identity is considered to be the aggregate of characteristics by which a structure is recognized.


backward locomotion

Posterior movement of an organism, e.g. following the direction of the tail of an animal.


regulation of chemotaxis

Any process that modulates the frequency, rate or extent of the directed movement of a motile cell or organism in response to a specific chemical concentration gradient.


establishment of epithelial cell polarity

The specification and formation of anisotropic intracellular organization of an epithelial cell.


elaioplast organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an elaioplast, a leucoplast in which oil is stored.


anterior region determination

Specification of the anterior (head and thoracic segments) of the embryo by the gap genes; exemplified in insects by the actions of hunchback gene product.


establishment of neuroblast polarity

The specification and formation of the apicobasal polarity of a neuroblast cell, a progenitor of the central nervous system.


sorbitol metabolic process

The chemical reactions and pathways involving sorbitol (D-glucitol), one of the ten stereoisomeric hexitols. It can be derived from glucose by reduction of the aldehyde group.


phenylpropanoid metabolic process

The chemical reactions and pathways involving aromatic derivatives of trans-cinnamic acid.


cytoophidium organization

A process which results in the assembly, arrangement of constituent parts, or disassembly of a cytoophidium. Cytoophidia are mesoscale, intracellular, filamentous structures that contain metabolic enzymes.


structural constituent of cuticle

The action of a molecule that contributes to the structural integrity of a cuticle.


single-species biofilm formation on inanimate substrate

A process in which microorganisms of the same species attach to and grow on an inanimate surface such as a rock or pipe, and produce extracellular polymers that facilitate attachment and matrix formation, resulting in an alteration in the phenotype of the organisms with respect to growth rate and gene transcription.


response to lapatinib

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lapatinib stimulus.


chloral hydrate dehydrogenase activity

Catalysis of the reactions: chloral hydrate = 3 H+ + 2 e- + trichloroacetate, and chloral hydrate + H2 = H2O + trichloroethanol.


maintenance of right sidedness

The organization process that preserves the right sidedness in an organism's body plan or part of an organism with respect to the left and right halves.


chlorobenzene metabolic process

The chemical reactions and pathways involving chlorobenzene, a derivative of benzene with a chlorine atoms attached to the ring. It is a colorless liquid that is manufactured for use as a solvent. It quickly evaporates in the air and is degraded by hydroxyl radicals that are produced photochemically. The gas acts as a source of ClOx, which helps in the breakdown of stratospheric ozone.


positive regulation of excitatory postsynaptic potential

Any process that enhances the establishment or increases the extent of the excitatory postsynaptic potential (EPSP) which is a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential.


detection of hormone stimulus

The series of events in which a hormone stimulus is received by a cell and converted into a molecular signal.


cell communication

Any process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.


Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = diphosphate + (2S,3R,6S,9S)-(-)-protoillud-7-ene.


inductive cell-cell signaling

Signaling at short range between cells of different ancestry and developmental potential that results in one cell or group of cells effecting a developmental change in the other. This is often done by secretion of proteins by one cell which affects the neighboring cells and causes them to adopt a certain fate.


Catalysis of the reaction: 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetate + ATP + CoA = AMP + diphosphate + 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA.


trypanothione metabolic process

The chemical reactions and pathways involving trypanothione (N1,N6,-bis(glutathionyl)spermidine), an essential redox intermediate in intracellular thiol redox regulation which also plays a role in protecting against oxidative stress.


positive regulation of endothelial cell activation

Any process that activates or increases the frequency, rate or extent of endothelial cell activation.


FasL biosynthetic process

The chemical reactions and pathways resulting in the formation of fas ligand (FasL or CD95L), an antigen originally found to be expressed on the cell surface of activated human T-lymphocytes and B-lymphocytes and a variety of malignant human lymphoid cell lines.


axial mesoderm morphogenesis

The process in which the anatomical structures of the axial mesoderm are generated and organized.


fumiquinazoline C biosynthetic process

The chemical reactions and pathways resulting in the formation of the indole alkaloid fumiquinazoline C.


disruption by symbiont of host cell envelope

The process by which a symbiont breaks down the cell wall of its host. The host is defined as the larger of the organisms involved in a symbiotic interaction.


Catalysis of the reaction: N-methylethanolamine phosphate + CTP = CDP-N-methylethanolamine + diphosphate.


protein-phosphocysteine-glucosamine phosphotransferase system transporter activity

Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + glucosamine (out) = protein cysteine + glucosamine-6-phosphate (in).


iron incorporation into iron-sulfur cluster via tetrakis-L-cysteinyl tetrairon tetrasulfide

The incorporation of iron into a 4Fe-4S iron-sulfur cluster via tetrakis-L-cysteinyl tetrairon tetrasulfide.


chemorepulsion involved in precerebellar neuron migration

The creation and reception of signals that repel a precerebellar neuron as a component of the process of tangential migration.


lipoprotein particle binding

Binding to a lipoprotein particle. A lipoprotein particle, also known as a lipoprotein, is a clathrate complex consisting of a lipid enwrapped in a protein host without covalent binding in such a way that the complex has a hydrophilic outer surface consisting of all the protein and the polar ends of any phospholipids.


salicylic acid metabolic process

The chemical reactions and pathways involving of salicylic acid (2-hydroxybenzoic acid), a derivative of benzoic acid.


L-threonine catabolic process to propionate

The chemical reactions and pathways resulting in the breakdown of L-threonine (the L-enantiomer of 2-amino-3-hydroxybutyric acid) to form the compound propionate.


cellular response to L-phenylalanine derivative

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-phenylalanine derivative stimulus.


heptadec-1-ene metabolic process

The chemical reactions and pathways involving heptadec-1-ene.


acetoin catabolic process

The chemical reactions and pathways resulting in the breakdown of acetoin, 3-hydroxy-2-butanone.


CDP metabolic process

The chemical reactions and pathways involving CDP, cytidine (5'-)diphosphate.


response to miconazole

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a miconazole stimulus.


O-glycan processing, core 5

The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form the core 5 O-glycan structure, GalNAc-alpha-(1->3)-GalNAc.


sequestering of BMP from receptor via BMP binding

Binding to a bone morphogenetic protein (BMP) in the extracellular region, and inhibiting BMP signaling by preventing BMP from binding to its cell surface receptor.


malonate(1-) transmembrane transporter activity

Enables the transfer of malonate(1-) from one side of a membrane to the other.


dichotomous subdivision of terminal units involved in lung branching

The process in which a lung bud bifurcates.


Wnt signaling pathway involved in heart development

The series of molecular signals initiated by binding of Wnt protein to a receptor on the surface of the target cell, resulting a change in cell state that contributes to the progression of the heart over time.


tyrosine ammonia-lyase activity

Catalysis of the reaction: L-tyrosine = NH4 + trans-4-coumarate.


receptor diffusion trapping

The process by which a membrane receptor, diffusing freely within the plasma membeane, becomes trapped in some plasma membrane region. This can happen when a receptor bind, directly or indirectly, to some component of the underlying matrix.


purine nucleotide transmembrane transporter activity

Enables the transfer of a purine nucleotide, any compound consisting of a purine nucleoside esterified with (ortho)phosphate, from one side of a membrane to the other.


regulation of response to DNA integrity checkpoint signaling

Any process that modulates the frequency, rate or extent of response to DNA integrity checkpoint signaling.


5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate catabolic process

The chemical reactions and pathways resulting in the breakdown of 5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate.


ABC-type guanine transporter activity

Catalyses the reaction: ATP + H2O + guanine(out) = ADP + phosphate + guanine(in).


threonine-type endopeptidase activity

Catalysis of the hydrolysis of internal peptide bonds in a polypeptide chain by a mechanism in which the hydroxyl group of a threonine residue at the active center acts as a nucleophile.


indoleacetamide hydrolase activity

Catalysis of the reaction: indole-3-acetamide + H2O = indole-3-acetate + NH3. Indole-3-acetamide is known as IAM and indole-3-acetate as IAA.


mismatch repair complex binding

Binding to a mismatch repair complex.


ABC-type glycerol-3-phosphate transporter activity

Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + glycerol-3-phosphate(out) = ADP + phosphate + glycerol-3-phosphate(in).


macrophage differentiation

The process in which a relatively unspecialized monocyte acquires the specialized features of a macrophage.


4-hydroxyproline biosynthetic process

The chemical reactions and pathways resulting in the formation of 4-hydroxyproline, C5H9NO3, a derivative of the amino acid proline.


Catalysis of the reaction: 2-demethylmenaquinone + S-adenosyl-L-methionine = menaquinone + S-adenosyl-L-homocysteine.


carnitine metabolic process, CoA-linked

The chemical reactions and pathways involving carnitine, where metabolism is linked to CoA.


parahippocampal gyrus development

The progression of the parahippocampal gyrus over time from its initial formation until its mature state. The parahippocampal gyrus is a ridge in the cerebral cortex.


positive regulation of cold-induced thermogenesis

Any process that activates or increases the frequency, rate or extent of cold-induced thermogenesis.


structural constituent of synapse

The action of a molecule that contributes to the structural integrity of a synapse.


dendritic cell antigen processing and presentation

The process in which a dendritic cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex.


protein carrier chaperone

Binding to and carrying a protein between two different cellular components by moving along with the target protein.


Catalysis of the reaction: UDP-alpha-D-glucose + 7,8-dihydroxycoumarin <=> UDP + 4-O- beta -D-glucosyl-daphnetin + H+.


clustering of voltage-gated calcium channels

The process in which voltage-gated calcium channels become localized together in high densities.


cytochrome bo3 ubiquinol oxidase activity

Catalysis of the reaction: 2 ubiquinol + O2 + 4 H+ = 2 ubiquinone + 2 H2O + 4 H+ [periplasmic space].


plasma membrane raft organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of plasma membrane rafts.


regulation of branchiomeric skeletal muscle development

Any process that modulates the frequency, rate or extent of branchiomeric skeletal muscle development. Branchiomeric skeletal muscle development is the process whose specific outcome is the progression of the branchiomeric skeletal muscle over time, from its formation to the mature structure.


adhesion of symbiont infection cushion to host

The attachment of an infection cushion of the symbiont to its host via adhesion molecules. The host is defined as the larger of the organisms involved in a symbiotic interaction.


maintenance of protein location in extracellular region

Any process in which a protein is maintained in a specific location within the extracellular region and is prevented from moving elsewhere.


peptidyl-L-3',4'-dihydroxyphenylalanine biosynthetic process from peptidyl-tyrosine

The modification of protein tyrosine to peptidyl-L-3',4'-dihydroxyphenylalanine (DOPA).


D-galacturonate reductase activity

Catalysis of the reaction: L-galactonate + NADP = aldehydo-D-galacturonate + NADPH + H+.


histone H4 acetyltransferase activity

Catalysis of the reaction: acetyl-CoA + histone H4 = CoA + acetyl-histone H4.


regulation of osmolarity-sensing cation channel activity

Any process that modulates the frequency, rate or extent of osmolarity-sensing cation channel activity.


thyroid-stimulating hormone signaling pathway

A G protein-coupled receptor signaling pathway initiated by thyroid-stimulating hormone (thyrotropin) binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.


cellular response to sodium arsenite

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sodium arsenite stimulus.


thiosulfate dehydrogenase (quinone) activity

Catalysis of the reaction: 6-decylubiquinone + 2 thiosulfate = 6-decylubiquinol + tetrathionate.


negative regulation of apoptotic process involved in outflow tract morphogenesis

Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in outflow tract morphogenesis.


retrograde extension

The progression of a neuronal projection over time by the attachment of a part of the cell to an anchor and the subsequent migration of the cell body away from the anchor point.


regulation of systemic arterial blood pressure by endothelin

The process in which endothelin modulates the force with which blood passes through the circulatory system. Endothelin is a hormone that is released by the endothelium, and it is a vasoconstrictor.


DNA synthesis involved in double-strand break repair via single-strand annealing

The synthesis of DNA that contributes to the process of double-strand break repair via single-strand annealing.


habenula development

The progression of the habenula over time from its initial formation until its mature state. The habenula is the group of nuclei that makes up the stalk of the pineal gland.


acyl-glucuronidase activity

Catalysis of the reaction: an acyl-glucuronoside + H2O = an alcohol + D-glucuronate.


response to isoquinoline alkaloid

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an isoquinoline alkaloid stimulus. An isoquinoline alkaloid is any member of a group of compounds with the heterocyclic ring structure of benzo(c)pyridine which is a structure characteristic of the group of opium alkaloids.


regulation of glutamate-cysteine ligase activity

Any process that modulates the activity of glutamate-cysteine ligase.


dendritic cell apoptotic process

Any apoptotic process in a dendritic cell, a cell of hematopoietic origin, typically resident in particular tissues, specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation.


ncRNA 5'-end processing

Any process involved in forming the mature 5' end of a non-coding RNA molecule.


negative regulation of developmental vegetative growth

Any process that stops, prevents or reduces the frequency, rate or extent of developmental vegetative growth.


transcription regulatory region nucleic acid binding

Binding to a nucleic acid region that regulates a nucleic acid-based process. Such processes include transcription, DNA replication, and DNA repair.


cerebellar molecular layer structural organization

The process that contributes to the act of creating the structural organization of the cerebellar molecular layer. This process pertains to the physical shaping of a rudimentary structure. The molecular layer is the outermost layer of the cerebellar cortex. It contains the parallel fibers of the granule cells, interneurons such as stellate and basket cells, and the dendrites of the underlying Purkinje cells.


Notch signaling pathway involved in somitogenesis

Any Notch signaling pathway that is involved in somitogenesis.


[acetyl-CoA carboxylase] kinase activity

Catalysis of the reaction: ATP + [acetyl-CoA carboxylase] = ADP + [acetyl-CoA carboxylase] phosphate.


cilium attachment to cell body

A process that is carried out at the cellular level which results in the lateral attachment of the cilium to the cell body via the flagellar attachment zone in some trypanosomatid species.


fructose 1,6-bisphosphate metabolic process

The chemical reactions and pathways involving fructose 1,6-bisphosphate, also known as FBP. The D enantiomer is a metabolic intermediate in glycolysis and gluconeogenesis.


CDP phosphatase activity

Catalysis of the reaction: CDP + H2O = CMP + phosphate.


Catalysis of the transfer of an alpha-D-glucosyl residue from dolichyl-phosphate D-glucose into a membrane lipid-linked oligosaccharide.


visceral muscle development

The process whose specific outcome is the progression of the visceral muscle over time, from its formation to the mature structure.


tobramycin metabolic process

The chemical reactions and pathways involving tobramycin.


positive regulation of cardiac muscle tissue regeneration

Any process that activates or increases the frequency, rate or extent of cardiac muscle tissue regeneration.


jasmonic acid mediated signaling pathway

The series of molecular signals mediated by jasmonic acid.


fructokinase activity

Catalysis of the reaction: ATP + D-fructose = ADP + D-fructose 6-phosphate.


negative regulation of natural killer cell tolerance induction

Any process that stops, prevents, or reduces the frequency, rate, or extent of natural killer cell tolerance induction.


negative regulation of fibroblast proliferation

Any process that stops, prevents, or reduces the frequency, rate or extent of multiplication or reproduction of fibroblast cells.


nopaline catabolic process to proline

The chemical reactions and pathways resulting in the breakdown of nopaline into other compounds, including proline.


lactate metabolic process

The chemical reactions and pathways involving lactate, the anion of lactic acid.


monoamine transmembrane transporter activity

Enables the transfer of monoamines, organic compounds that contain one amino group that is connected to an aromatic ring by an ethylene group (-CH2-CH2-), from one side of a membrane to the other.


tricuspid valve formation

The developmental process pertaining to the initial formation of the tricuspid valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable.


capsanthin catabolic process

The chemical reactions and pathways resulting in the breakdown of capsanthin.


regulation of extrinsic apoptotic signaling pathway

Any process that modulates the frequency, rate or extent of extrinsic apoptotic signaling pathway.


Catalysis of the reaction: 3-dehydro-L-gulonate 6-phosphate + H+ = L-xylulose 5-phosphate + CO2.


regulation of 1-deoxy-D-xylulose-5-phosphate synthase activity

Any process that modulates the frequency, rate or extent of 1-deoxy-D-xylulose-5-phosphate synthase activity.


positive regulation of aggregation involved in sorocarp development

Any process that increases the frequency, rate or extent of aggregation involved in sorocarp development. Aggregation involved in sorocarp development is the process whose specific outcome is the progression of the aggregate over time, from its formation to the point when a slug is formed. Aggregate development begins in response to starvation and continues by the chemoattractant-mediated movement of cells toward each other. The aggregate is a multicellular structure that gives rise to the slug.


glucosinolate glucohydrolase activity

Catalysis of the reaction: H2O + a glucosinolate = alpha-D-glucose + a thiohydroximate-O-sulfate. Glucosinolates are a subclass of thioglucosides.


selenol Se-methyltransferase activity

Catalysis of the reaction: R + Se-Adenosylselenomethionine => CH3-R + Se-Adenosyl-L-selenohomocysteine.


Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: urea(out) + Na+(out) = urea(in) + Na+(in).


pupal development

The process whose specific outcome is the progression of the pupa over time, from its formation to the mature structure. The pupa is a dormant life stage interposed between the larval and the adult stages in insects that undergo a complete metamorphosis.


somatotropin secreting cell differentiation

The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a somatotropin secreting cell. A somatotropin secreting cell is an acidophilic cell of the anterior pituitary that produces growth hormone, somatotropin.


response to L-phenylalanine derivative

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-phenylalanine derivative stimulus.


L-fuculose-phosphate aldolase activity

Catalysis of the reaction: L-fuculose 1-phosphate = (S)-lactaldehyde + glycerone phosphate.


cellular developmental process

A biological process whose specific outcome is the progression of a cell over time from an initial condition to a later condition.


maltose phosphorylase activity

Catalysis of the reaction: maltose + phosphate = D-glucose + beta-D-glucose 1-phosphate.


L-ascorbic acid transmembrane transporter activity

Enables the transfer of L-ascorbate from one side of a membrane to the other. L-ascorbate, (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate, is vitamin C and has co-factor and anti-oxidant activities in many species.


adenosine-tetraphosphatase activity

Catalysis of the reaction: adenosine 5'-tetraphosphate + H2O = ATP + phosphate.


neural fold formation

The process in which the neural fold is formed. The edges of the neural plate thicken and move up to form a U-shaped structure called the neural groove.


positive regulation of fat cell apoptotic process

Any process that activates or increases the frequency, rate or extent of fat cell apoptotic process.


rectal diverticulum development

The process whose specific outcome is the progression of the rectal diverticulum over time, from its formation to the mature structure. The rectal diverticulum is an outgrowth of the cloaca and links the pronephric kidney to the exterior.


choline biosynthetic process

The chemical reactions and pathways resulting in the formation of choline (2-hydroxyethyltrimethylammonium), an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids and in the neurotransmitter acetylcholine.


positive regulation of aorta morphogenesis

Any process that activates or increases the frequency, rate or extent of aorta morphogenesis.


The chemical reactions and pathways involving 5,6,7,8-tetrahydrosarcinapterin.


myeloid dendritic cell differentiation

The process in which a monocyte acquires the specialized features of a dendritic cell, an immunocompetent cell of the lymphoid and hemopoietic systems and skin.


transcription regulator activity

A molecular function that controls the rate, timing and/or magnitude of gene transcription. The function of transcriptional regulators is to modulate gene expression at the transcription step so that they are expressed in the right cell at the right time and in the right amount throughout the life of the cell and the organism. Genes are transcriptional units, and include bacterial operons.


positive regulation of locomotion involved in locomotory behavior

Any process that increases the frequency, rate, or extent of the self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement.


Catalysis of the reaction: dihydrophloroglucinol + OH- = 3-hydroxy-5-oxohexanoate.


glial cell differentiation involved in amphid sensory organ development

The process in which a relatively unspecialized cell acquires the specialized features of a glial cell of the amphid sensory organ.


Catalysis of the reaction: delphinidin 3-O-glucosyl-5-O-(caffeoylglucoside-3'-O-glucoside) + caffeoyl-CoA <=> gentiodelphin + coenzyme A.


positive regulation of hormone secretion

Any process that activates or increases the frequency, rate or extent of the regulated release of a hormone from a cell.


Catalysis of the reaction: NAD(P)+ + 17-alpha,20-alpha-dihydroxypregn-4-en-3-one = NAD(P)H + H+ + 17-alpha-hydroxyprogesterone.


endoplasmic reticulum tubular network maintenance

The organization process that preserves the endoplasmic reticulum (ER) tubular network in a stable functional or structural state. The ER tubular network is the ER part that comprises the membranes with high curvature in cross-section.


positive regulation of myeloid leukocyte differentiation

Any process that activates or increases the frequency, rate, or extent of myeloid leukocyte differentiation.


The chemical reactions and pathways resulting in the formation of 2-hydroxybenzoyl-CoA.


maleylpyruvate isomerase activity

Catalysis of the reaction: 3-maleylpyruvate = 3-fumarylpyruvate.


cytosine biosynthetic process

The chemical reactions and pathways resulting in the formation of cytosine, 4-amino-2-hydroxypyrimidine, a pyrimidine derivative that is one of the five main bases found in nucleic acids; it occurs widely in cytidine derivatives.


tolerance induction to nonself antigen

Tolerance induction in response to nonself antigens.


venous blood vessel morphogenesis

The process in which the anatomical structures of venous blood vessels are generated and organized. Veins are blood vessels that transport blood from the body and its organs to the heart.


regulation of interleukin-6-mediated signaling pathway

Any process that modulates the rate, frequency or extent of an interleukin-6-mediated signaling pathway.


Catalysis of the reaction: L-alanine + H+ + pimelyl-CoA = 8-amino-7-oxononanoate + CO2 + CoA.


thiamine-phosphate kinase activity

Catalysis of the reaction: ATP + thiamine phosphate = ADP + H+ + thiamine diphosphate.


xenobiotic catabolic process

The chemical reactions and pathways resulting in the breakdown of a xenobiotic compound, a compound foreign to the organim exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical.


response to humidity

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a humidity stimulus, moisture in the atmosphere.


cellular response to progesterone stimulus

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a progesterone stimulus.


nucleotide-excision repair, preincision complex assembly

The aggregation, arrangement and bonding together of proteins on DNA to form the multiprotein complex involved in damage recognition, DNA helix unwinding, and endonucleolytic cleavage at the site of DNA damage. This assembly occurs before the phosphodiester backbone of the damaged strand is cleaved 3' and 5' of the site of DNA damage.


negative regulation of renal phosphate excretion

Any process that stops, prevents or reduces the frequency, rate or extent of renal phosphate excretion.


positive regulation of cardiac chamber formation

Any process that activates or increases the frequency, rate or extent of cardiac chamber formation.


branching involved in seminal vesicle morphogenesis

The process in which the branching structure of the seminal vesicle is generated and organized. A branch is a division or offshoot from a main stem.


response to hyperoxia

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating increased oxygen tension.


negative regulation of potassium ion transmembrane transporter activity

Any process that stops, prevents or reduces the frequency, rate or extent of potassium ion transmembrane transporter activity.


negative regulation of bud outgrowth involved in lung branching

Any process that decreases the rate, frequency, or extent of bud outgrowth involved in lung branching.


renal water homeostasis

Renal process involved in the maintenance of an internal steady state of water in the body.


dihydropteridine metabolic process

The chemical reactions and pathways involving 6,7-dihydropteridine, a bicyclic compound with the formula C6H6N4.


dendritic spine development

The process whose specific outcome is the progression of the dendritic spine over time, from its formation to the mature structure. A dendritic spine is a protrusion from a dendrite and a specialized subcellular compartment involved in synaptic transmission.


response to oleic acid

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oleic acid stimulus.


alpha-beta T cell differentiation involved in immune response

The process in which an antigenically naive alpha-beta T cell acquires the specialized features of an effector, regulatory, or memory T cell during an immune response. Effector T cells include cells which provide T cell help or exhibit cytotoxicity towards other cells.


protein localization to endosome

A process in which a protein is transported to, or maintained in, a location within an endosome.


transporter activity

Enables the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells.


memory T cell differentiation

The process in which a newly activated T cell acquires specialized features of a memory T cell.


envenomation resulting in modulation of ion channel activity in another organism

A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant change in the activity of an ion channel in the bitten organism.


histone H4K16 deacetylase activity

Catalysis of the reaction: histone H4 N6-acetyl-L-lysine (position 16) + H2O = histone H4 L-lysine (position 16) + acetate. This reaction represents the removal of an acetyl group from lysine at position 16 of the histone H4 protein.


positive regulation of serotonin secretion

Any process that activates or increases the frequency, rate or extent of the regulated release of serotonin.


dedifferentiation

The process in which a specialized structure (cell, tissue or organ) loses structural or functional features that characterize it in the mature organism, or some other relatively stable phase of the organism's life history. Under certain conditions, these structures can revert back to the features of their ancestors.


adhesion of symbiont to host cell surface via host glycoprotein

The attachment of a symbiont to its host by binding to a glycoprotein on the host cell surface. The host is defined as the larger of the organisms involved in a symbiotic interaction.


Catalysis of the reaction: 3,4-dihydroxyphthalate + H+ = 3,4-dihydroxybenzoate + CO2.


plus-end specific microtubule depolymerization

The removal of tubulin heterodimers from the plus end of a microtubule.


thyroid gland development

The process whose specific outcome is the progression of the thyroid gland over time, from its formation to the mature structure. The thyroid gland is an endoderm-derived gland that produces thyroid hormone.


rejection of self pollen

The recognition and rejection of self pollen by cells in the stigma, mediated by the sharing and interaction of the single locus incompatibility haplotypes.


Catalysis of the reaction: 10-hydroxydihydrosanguinarine + S-adenosyl-L-methionine(1+) = S-adenosyl-L-homocysteine + dihydrochelirubine + H+.


positive regulation of respiratory burst

Any process that increases the rate frequency or extent of a phase of elevated metabolic activity, during which oxygen consumption increases; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals.


L-altrarate dehydratase activity

Catalysis of the reaction: L-altrarate = 5-dehydro-4-deoxy-D-glucarate + H2O.


regulation of shoot system morphogenesis

Any process that modulates the frequency, rate or extent of shoot morphogenesis.


N-acetyllactosamine synthase activity

Catalysis of the reaction: UDP-galactose + N-acetyl-D-glucosamine = UDP + N-acetyllactosamine.


taurocyamine kinase activity

Catalysis of the reaction: ATP + taurocyamine = N-phosphotaurocyamine + ADP + 2 H+.


prothoracic disc morphogenesis

The process in which the anatomical structures derived from the prothoracic disc are generated and organized. This includes the transformation of a prothoracic imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into the recognizable adult humerous and anterior spiracle.


terpenoid biosynthetic process, mevalonate-independent

The chemical reactions and pathways resulting in the formation of terpenoids, independent of mevalonate. Isopentenyl diphosphate (IPP) is the fundamental unit in terpenoid biosynthesis, and in mevalonate-independent biosynthesis, it is produced from pyruvate and glyceraldehyde 3-phosphate via intermediates including 1-deoxy-D-xylulose 5-phosphate.


suppression by virus of host peptidoglycan biosynthetic process

Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of peptidoglycan biosynthesis in the host organism. Peptidoglycans are any of a class of glycoconjugates found in bacterial cell walls.


L-hydroxyproline transmembrane transporter activity

Enables the transfer of L-hydroxyproline from one side of a membrane to the other.


dTMP metabolic process

The chemical reactions and pathways involving dTMP, deoxyribosylthymine monophosphate (2'-deoxyribosylthymine 5'-phosphate).


Catalysis of the reaction: 2 (4-hydroxyphenyl)pyruvate + O2 = 2 (4-hydroxyphenyl)acetate + 2 CO2.


Catalysis of the reaction: 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + L-lysyl-tRNA(Lys) = 1,2-diacyl-sn-glycero-3-phospho-1'-(3'-O-L-lysyl)-sn-glycerol + tRNA(Lys).


Catalysis of the reaction: 1-acyl-sn-glycero-3-phosphocholine + acyl-CoA = phosphatidylcholine + CoA.


negative regulation of neural precursor cell proliferation

Any process that stops, prevents, or reduces the frequency, rate or extent of neural precursor cell proliferation.


intracellular cAMP-activated cation channel activity

Enables the transmembrane transfer of a cation by a channel that opens when intracellular cAMP has been bound by the channel complex or one of its constituent parts.


negative regulation of positive thymic T cell selection

Any process that stops, prevents or reduces the frequency, rate or extent of positive thymic T cell selection.


15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity

Catalysis of the reaction: NADP+ + (5Z,13E)-(15S)-9-alpha,15-dihydroxy-11-oxoprosta-5,13-dienoate = NADPH + H+ + (5Z,13E)-9-alpha-hydroxy-11,15-dioxoprosta-5,13-dienoate.


ribonuclease M5 activity

Catalysis of the endonucleolytic cleavage of RNA, removing 21 and 42 nucleotides, respectively, from the 5'- and 3'-termini of a 5S-rRNA precursor.


uracil biosynthetic process

The chemical reactions and pathways resulting in the formation of uracil, 2,4-dioxopyrimidine, one of the pyrimidine bases occurring in RNA, but not in DNA.


pancreas field specification

The process in which a specific region of the gut is delineated into the area in which the pancreas will develop.


L-cysteine catabolic process via cystine, using cystine reductase

The chemical reactions and pathways resulting in the breakdown, via the compound cystine, of L-cysteine, catalyzed by the enzyme cystine reductase.


globus pallidus development

The progression of the globus pallidus over time from its initial formation until its mature state. The globus pallidus is one of the basal ganglia involved with control of voluntary movement in the brain.


peptide receptor activity

Combining with an extracellular or intracellular peptide to initiate a change in cell activity.


peptidyl-lysine acetylation

The acetylation of peptidyl-lysine.


cell communication by chemical coupling

The process that mediates signaling interactions between one cell and another cell by the transfer of small, water-soluble molecules or metabolites between their adjacent cytoplasms via intercellular protein channels.


negative regulation of nigerotriose transport

Any process that stops, prevents or reduces the frequency, rate or extent of nigerotriose transport.


negative regulation of acetylcholine-gated cation channel activity

Any process that stops, prevents or reduces the frequency, rate or extent of acetylcholine-gated cation channel activity.


negative regulation of pancreatic stellate cell proliferation

Any process that stops, prevents, or reduces the frequency, rate or extent of pancreatic stellate cell proliferation.


regulation of synaptic metaplasticity

A process that modulates synaptic metaplasticity. Metaplasticity is a higher-order form of plasticity and is manifest as a change in the ability to induce subsequent synaptic plasticity that is the ability of synapses to change as circumstances require.


shade avoidance

Shade avoidance is a set of responses that plants display when they are subjected to the shade of another plant. It often includes elongation, altered flowering time, increased apical dominance and altered partitioning of resources. Plants are able to distinguish between the shade of an inanimate object (e.g. a rock) and the shade of another plant due to the altered balance between red and far-red light in the shade of a plant; this balance between red and far-red light is perceived by phytochrome.


intracellular lysine homeostasis

A homeostatic process involved in the maintenance of a steady state level of lysine within a cell.


mycothiol-arsenate ligase activity

Catalysis of the reaction: arsenate + mycothiol <=> mycothiol-arsenate conjugate + H2O.


positive regulation of cell development

Any process that increases the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.


cellular response to desipramine

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a desipramine stimulus.


negative regulation of CD4-positive, alpha-beta T cell differentiation

Any process that stops, prevents, or reduces the frequency, rate, or extent of CD4-positive, alpha-beta T cell differentiation.


convergent extension involved in neural plate elongation

The process of directed cell movement in the neural plate resulting in tissue elongation via intercalation of adjacent cells in an epithelial sheet at the midline, leading to narrowing and lengthening of the neural plate.


de novo centriole assembly involved in multi-ciliated epithelial cell differentiation

Centriole assembly in which a centriole arises de novo by a process involving an electron-dense structure known as a deuterosome, rather than by duplication of an existing centriole, and occurring as part of multi-ciliated epithelial cell differentiation.


negative regulation of pyroptosis

Any process that decreases the frequency, rate or extent of pyroptosis.


response to decreased oxygen levels

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting a decline in the level of oxygen.


Catalysis of the reaction: 2-(hydroxymethyl)glutarate + NAD+ = 2-formylglutarate + H+ + NADH.


positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway

Any process that activates or increases the frequency, rate or extent of oxidative stress-induced neuron intrinsic apoptotic signaling pathway.


positive energy taxis

The directed movement of a motile cell or organism towards a higher level of a physical stimulus involved in energy generation, such as light, oxygen, and oxidizable substrates.


chloroplast photosystem I binding

Binding to a chloroplast photosystem I.


immature T cell proliferation

The expansion of an immature T cell population by cell division.


phytoalexin biosynthetic process

The chemical reactions and pathways resulting in the formation of phytoalexins, any of a range of substances produced by plants as part of their defense response.


activation of blood coagulation via clotting cascade

Any process that initiates the clotting cascade of blood coagulation, a cascade of plasma enzymes that is triggered following damage to blood vessels, leading to formation of a clot.


protein localization to microtubule

A process in which a protein is transported to, or maintained at, a microtubule.


negative regulation of intraciliary retrograde transport

Any process that stops, prevents or reduces the frequency, rate or extent of intraciliary retrograde transport.


Catalysis of the reaction: 1-phenanthrol + X-CH3 = X + 1-methoxyphenanthrene.


negative regulation of synaptic transmission

Any process that stops, prevents, or reduces the frequency, rate or extent of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse.


negative regulation of sporulation resulting in formation of a cellular spore

Any process that stops, prevents, or reduces the frequency, rate or extent of sporulation.


cellular response to disaccharide stimulus

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disaccharide stimulus.


regulation of distal tip cell migration

Any process that modulates the frequency, rate or extent of distal tip cell migration.


sweat gland development

The progression of the sweat gland over time, from its formation to the mature structure. Sweat glands secrete an aqueous solution that is used in thermoregulation.


tolerance induction to lipopolysaccharide

Tolerance induction directed at lipopolysaccharide antigens.


glucose 1-dehydrogenase (NADP+) activity

Catalysis of the reaction: D-glucose + NADP+ = D-glucono-1,5-lactone + NADPH.


Catalysis of the reaction: feruloyl-CoA + quinate = O-feruloylquinate + CoA.


negative regulation of defense response to insect

Any process that stops, prevents or reduces the frequency, rate or extent of defense response to insect.


negative regulation of chemokine-mediated signaling pathway

Any process that decreases the rate, frequency or extent of a chemokine-mediated signaling pathway.


pyochelin catabolic process

The chemical reactions and pathways resulting in the breakdown of the siderochrome pyochelin (2-(2-o-hydroxyphenyl-2-thiazolin-4-yl)-3-methylthiazolidine-4-carboxylic acid).


tubulin-glycine ligase activity

Catalysis of the posttranslational transfer of one or more glycine residues to a specific glutamate residue on a target tubulin molecule; acts on alpha or beta tubulin.


determination of sensory modality

The determination of the type or quality of a sensation. Sensory modalities include touch, thermal sensation, visual sensation, auditory sensation and pain.


inner ear receptor cell differentiation involved in inner ear sensory epithelium regeneration

Differentiation of new inner ear sensory hair cells to replace those lost or destroyed by injury.


cellular response to glucoside

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucoside stimulus.


neutral lipid biosynthetic process

The chemical reactions and pathways resulting in the formation of neutral lipids, lipids only soluble in solvents of very low polarity.


fasciculation of motor neuron axon

The collection of motor neuron axons into a bundle of rods, known as a fascicle.


ethylene receptor activity

Combining with ethylene and transmitting the signal in the cell to initiate a change in cell activity.


7-oxateasterone synthase activity

Catalysis of the reaction: H+ + teasterone + NADPH + O2 <=> 7-oxateasterone + NADP + H2O.


oxidised low-density lipoprotein particle clearance

The process in which an oxidised low-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.


myoblast fate determination involved in skeletal muscle regeneration

The process in which a satellite cell becomes capable of differentiating autonomously into a myoblast regardless of its environment; upon determination, the cell fate cannot be reversed. This occurs as part of skeletal muscle regeneration. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.


Catalysis of the reaction: S-adenosyl-L-methionine + methylarsonite = S-adenosyl-L-homocysteine + dimethylarsinate.


skeletal muscle fiber differentiation

The process in which a relatively unspecialized cell acquires specialized features of a skeletal muscle fiber cell. Skeletal muscle fiber differentiation starts with myoblast fusion and the appearance of specific cell markers (this is the cell development step). Then individual skeletal muscle fibers fuse to form bigger myotubes and start to contract.


Catalysis of the reaction: L-homocysteine + glycine betaine = N,N-dimethylglycine + L-methionine.


glucuronate metabolic process

The chemical reactions and pathways involving glucuronate, any salt or ester of glucuronic acid, the uronic acid formally derived from glucose by oxidation of the hydroxymethylene group at C-6 to a carboxyl group.


adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains

An immune response mediated by lymphocytes expressing specific receptors for antigen produced through a somatic diversification process that includes somatic recombination of germline gene segments encoding immunoglobulin superfamily domains. Recombined receptors for antigen encoded by immunoglobulin superfamily domains include T cell receptors and immunoglobulins (antibodies) produced by B cells. The first encounter with antigen elicits a primary immune response that is slow and not of great magnitude. T and B cells selected by antigen become activated and undergo clonal expansion. A fraction of antigen-reactive T and B cells become memory cells, whereas others differentiate into effector cells. The memory cells generated during the primary response enable a much faster and stronger secondary immune response upon subsequent exposures to the same antigen (immunological memory). An example of this is the adaptive immune response found in Mus musculus.


negative regulation of imaginal disc growth

Any process that stops, prevents, or reduces the frequency, rate or extent of imaginal disc growth.


asparagine metabolic process

The chemical reactions and pathways involving asparagine, 2-amino-3-carbamoylpropanoic acid.


positive regulation of cytokine-mediated signaling pathway

Any process that activates or increases the frequency, rate or extent of a cytokine mediated signaling pathway.


indolalkylamine biosynthetic process

The chemical reactions and pathways resulting in the formation of indolalkylamines, indole or indole derivatives containing a primary, secondary, or tertiary amine group.


N-methyl-L-amino-acid oxidase activity

Catalysis of the reaction: an N-methyl-L-amino acid + H2O + O2 = an L-amino acid + formaldehyde + H2O2.


actin filament fragmentation

The severing of actin filaments into numerous short fragments, usually mediated by actin severing proteins.


isoprene synthase activity

Catalysis of the reaction: dimethylallyl diphosphate = diphosphate + isoprene.


regulation of cytokinesis, site selection

Any process that modulates the frequency, rate or extent of site selection that occurs as part of cytokinesis.


iron incorporation into hydrogenase diiron subcluster via L-cysteine ligation

The incorporation of iron into an L-cysteinyl diiron subcluster, found in Fe-hydrogenase.


The chemical reactions and pathways involving 2-chloro-N-isopropylacetanilide, an acylanide herbicide widely used to protect corn, onion, cabbage, rose bushes, and ornamental plants.


regulation of cellular response to drug

Any process that modulates the frequency, rate or extent of cellular response to drug.


regulation of eosinophil differentiation

Any process that modulates the frequency, rate or extent of eosinophil differentiation.


androgen catabolic process

The chemical reactions and pathways resulting in the breakdown of androgens, C19 steroid hormones that can stimulate the development of male sexual characteristics.


N-carbamoyl-D-amino acid hydrolase activity

Catalysis of the reaction: H2O + N-carbamoyl-D-amino acid = CO2 + NH3 + D-amino acid.


arsenite transmembrane transporter activity

Enables the transfer of arsenite from one side of a membrane to the other.


quercetin gentiotrioside 1,6-glucosyltransferase activity

Catalysis of the reaction: quercetin-3-gentiotrioside + UDP-alpha-D-glucose <=> quercetin-3-gentiotetraside + UDP + H+.


Catalysis of the reaction: cis-9,10-dihydroanthracene-9,10-diol = 9,10-anthraquinone + 4 H+ + 4 e-.


vetispiradiene synthase activity

Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = diphosphate + vetispiradiene.


medulla oblongata morphogenesis

The process in which the anatomical structure of the medulla oblongata is generated and organized. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate.


leukocyte chemotaxis

The movement of a leukocyte in response to an external stimulus.


regulation of glucuronoxylan catabolic process

Any process that modulates the frequency, rate or extent of glucuronoxylan catabolic process.


Catalysis of the reaction: 2 glyoxylate + H+ = 2-hydroxy-3-oxopropanoate + CO2.


regulation of cell adhesion involved in single-species biofilm formation

Any process that modulates the frequency, rate or extent of cell adhesion involved in single-species biofilm formation.


negative regulation of cellular response to growth factor stimulus

Any process that decreases the rate, frequency, or extent of a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth factor stimulus.


Catalysis of the reaction: 2'-aminobiphenyl-2,3-diol + O2 = H+ + 2-hydroxy-6-oxo-(2'-aminophenyl)-hexa-2,4-dienoate.


nail development

The process whose specific outcome is the progression of a nail over time, from its formation to the mature structure. A nail is a horn-like envelope covering the outer end of a finger or toe, and consists of the nail plate, the nail matrix and the nail bed below it, and the grooves surrounding it.


meiotic prophase II

The cell cycle phase which is the first stage of meiosis II and during which chromosomes condense and the two daughter centrioles and their asters migrate toward the poles of the cell.


regulation of adenylate cyclase activity

Any process that modulates the frequency, rate or extent of adenylate cyclase activity.


ecdysone O-acyltransferase activity

Catalysis of the reaction: Ecdysone + palmitoyl-CoA = CoA + ecdysone palmitate.


agmatine kinase activity

Catalysis of the reaction: agmatine + ATP = N(4)-phosphoagmatine + ADP + 3 H+.


glycosphingolipid binding

Binding to glycosphingolipid, a compound with residues of sphingoid and at least one monosaccharide.


negative regulation of cell communication by electrical coupling involved in cardiac conduction

Any process that stops, prevents or reduces the frequency, rate or extent of cell communication by electrical coupling involved in cardiac conduction.


negative regulation of muscle contraction

Any process that stops, prevents, or reduces the frequency, rate or extent of muscle contraction.


positive regulation of nurse cell apoptotic process

Any process that activates or increases the frequency, rate or extent of nurse cell apoptotic process.


The chemical reactions and pathways resulting in the breakdown of 4-hydroxyphenylacetate.


lipopolysaccharide binding

Binding to a lipopolysaccharide.


cell wall polysaccharide metabolic process

The chemical reactions and pathways involving cell wall polysaccharides.


mithramycin dehydrogenase activity

Catalysis of the reaction: mithramycin + NADP = mithramycin DK + NADPH + H+.


apical constriction

The actin-mediated process that results in the contraction of the apical end of a polarized columnar epithelial cell.


Catalysis of the reaction: 2-methyl-6-phytyl-1,4-benzoquinone + S-adenosyl-methionine = 2,3-dimethyl-6-phytyl-1,4-benzoquinone + S-adenosyl-homocysteine.


primary cell septum disassembly

Dissolution of the primary septum during cell separation.