name: NAPEP_HUMAN N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D (sprot)

description: An N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D that is encoded in the genome of human.


name: NAPEP_MOUSE N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D (sprot)

description: An N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D that is encoded in the genome of mouse.


SDCB1_HUMAN Syntenin-1 (sprot)

A syntenin-1 that is encoded in the genome of human.


pregabalin

A gamma-amino acid that is gamma-aminobutyric acid (GABA) carrying an isobutyl substitutent at the beta-position (the S-enantiomer). Binds with high affinity to the alpha2-delta site (an auxiliary subunit of voltage-gated calcium channels) in central nervous system tissues.


name: TRPC3_MOUSE Short transient receptor potential channel 3 (sprot)

description: A short transient receptor potential cation channel TRPC3 that is encoded in the genome of mouse.


name: KCNT1_HUMAN Potassium channel subfamily T member 1 (sprot)

description: A potassium channel subfamily T member 1 that is encoded in the genome of human.


name: KCNT1_MOUSE Potassium channel subfamily T member 1 (sprot)

description: A potassium channel subfamily T member 1 that is encoded in the genome of mouse.


name: KCNT1_RAT Potassium channel subfamily T member 1 (sprot)

description: A potassium channel subfamily T member 1 that is encoded in the genome of rat.


name: KCNT2_HUMAN Potassium channel subfamily T member 2 (sprot)

description: A potassium channel subfamily T member 2 that is encoded in the genome of human.


name: CUTC_OLEA2 Choline trimethylamine-lyase (sprot)


Guanosine substituted with a methyl group at position N-1.


BETAINE ALDEHYDE

A quaternary ammonium ion that is nitrogen substituted by three methyl groups and a 2-oxoethyl group. It is an intermediate in the metabolism of amino acids like glycine, serine and threonine.


name: GP183_RAT G-protein coupled receptor 183 (sprot)

description: A G-protein coupled receptor 183 that is encoded in the genome of rat.


An oxysterol that is cholesterol which is substituted by hydroxy groups at the 7alpha and 26 positions.


A cembrane diterpenoid obtained from tobacco and shown to have antitumour-promoting activity.


name: FUBP1_HUMAN Far upstream element-binding protein 1 (sprot)

description: A far upstream element-binding protein 1 that is encoded in the genome of human.


name: NR4A3_HUMAN Nuclear receptor subfamily 4 group A member 3 (sprot)

description: A nuclear receptor subfamily 4 group A member 3 that is encoded in the genome of human.


RTN4_HUMAN Reticulon-4 (sprot)

A reticulon-4 that is encoded in the genome of human.


name: VAT1_HUMAN Synaptic vesicle membrane protein VAT-1 homolog (sprot)

description: A synaptic vesicle membrane protein VAT-1 that is encoded in the genome of human.


A thienopyrimidine that is thieno[3,2-d]pyrimidine which is substituted by a (carboxymethyl)sulfanediyl group at position 4 and by a 1-benzothiophen-2-yl group at position 6. It is a STK17B kinase inhibitor.


name: AFG32_HUMAN Mitochondrial inner membrane m-AAA protease component AFG3L2 (sprot)

description: An AFG3-like protein 2 that is encoded in the genome of human.


name: NMRL1_HUMAN NmrA-like family domain-containing protein 1 (sprot)

description: An NmrA-like family domain-containing protein 1 that is encoded in the genome of human.


name: FPR2_MOUSE Formyl peptide receptor 2 (sprot)

description: A protein that is a translation product of the Fpr2 gene in mouse.


name: IGA0_HAEIN Immunoglobulin A1 protease autotransporter (sprot)


name: bisphenol A (3-chloro-2-hydroxypropyl) (2,3-dihydroxypropyl) ether

description: The (3-chloro-2-hydroxypropyl) (2,3-dihydroxypropyl) diether of bisphenol A; a small molecule that inhibits transactivation of the AR amino-terminal domain (NTD).


name: NTM1B_HUMAN N-terminal Xaa-Pro-Lys N-methyltransferase 2 (sprot)

description: An N-terminal Xaa-Pro-Lys N-methyltransferase 2 that is encoded in the genome of human.


name: 4'-Hydroxy-biphenyl-3-carboxylic acid ethyl ester


name: 4'-Methyl-biphenyl-3-carboxylic acid ethyl ester


L-cysteine substituted at sulfur by a 2-boronoethyl group.


GIBBERELLIN A3

A C19-gibberellin that is a pentacyclic diterpenoid responsible for promoting growth and elongation of cells in plants.  Initially identified in Gibberella fujikuroi,it differs from gibberellin A1 in the presence of a double bond between C-3 and C-4.


name: CGT_HUMAN 2-hydroxyacylsphingosine 1-beta-galactosyltransferase (sprot)

description: A 2-hydroxyacylsphingosine 1-beta-galactosyltransferase that is encoded in the genome of human.


name: CGT_MOUSE 2-hydroxyacylsphingosine 1-beta-galactosyltransferase (sprot)

description: A 2-hydroxyacylsphingosine 1-beta-galactosyltransferase that is encoded in the genome of mouse.


name: RDRP_I34A1 RNA-directed RNA polymerase catalytic subunit (sprot)

description: An RNA-directed RNA polymerase catalytic subunit (Influenza A virus) that is encoded in the genome of the H1N1 strain A/Puerto Rico/8/1934.


name: Phenol, 2-methoxy-4-(2-nitroethenyl)-, propanoate (ester)


name: PRS6B_HUMAN 26S proteasome regulatory subunit 6B (sprot)

description: A 26S proteasome regulatory subunit 6B that is encoded in the genome of human.


RXFP1_RAT Relaxin receptor 1 (sprot)

A relaxin receptor 1 that is encoded in the genome of rat.


ranolazine

A racemate comprising equal amounts of (R)- and (S)-ranolazine. Used for treatment of chronic angina.


A diamino acid that is alanine in which one of the hydrogens of the methyl group is replaced by an amino group.


name: PTPRO_HUMAN Receptor-type tyrosine-protein phosphatase O (sprot)

description: A receptor-type tyrosine-protein phosphatase O that is encoded in the genome of human.


name: sigma1 Receptor/mu Opioid receptor modulator 1


ixabepilone

A macrocycle that is a lactam analogue of epothilone B. Binds directly to beta-tubulin subunits on microtubules, leading to suppression of microtubule dynamics.


name: FAA28_MYCTU Long-chain-fatty-acid--AMP ligase FadD28 (sprot)

description: A protein that is a translation product of the fadD28 gene in Mycobacterium tuberculosis H37Rv.


name: FAC19_MYCTU Medium/long-chain-fatty-acid--CoA/3-oxocholest-4-en-26-oate--CoA ligase (sprot)

description: A protein that is a translation product of the fadD19 gene in Mycobacterium tuberculosis H37Rv.


name: [(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl dodecyl hydrogen phosphate


name: FAA32_MYCTU Long-chain-fatty-acid--AMP ligase FadD32 (sprot)


tasquinimod

Tasquinimod is a quinoline-3-carboxamide linomide analogue with antiangiogenic and potential antineoplastic activities. Tasquinimod has been shown to decrease blood vessel density but the exact mechanism of action is not known. This agent has also been shown to augment the antineoplastic effects of docetaxel and androgen ablation in a murine model of prostate cancer involving human prostate cancer xenografts.


name: HDA10_DANRE Polyamine deacetylase HDAC10 (sprot)

description: A polyamine deacetylase HDAC10 that is encoded in the genome of zebrafish.


name: NPFF1_RAT Neuropeptide FF receptor 1 (sprot)

description: A neuropeptide FF receptor 1 that is encoded in the genome of rat.


A dipeptide resulting from the formal coupling of the carboxy group of N(2)-(diphenylacetyl)-D-arginine with the alpha-amino group of D-2-phenylglycinamide.


name: CXA1_HUMAN Gap junction alpha-1 protein (sprot)

description: A gap junction alpha-1 protein that is encoded in the genome of human.


name: SENP5_HUMAN Sentrin-specific protease 5 (sprot)

description: A sentrin-specific protease 5 that is encoded in the genome of human.


A member of the class of thianthrenes that is thianthrene substituted by a 4-oxo-6-(piperidin-1-yl)-4H-pyran-2-yl group at position 1. It is a weakly active inhibitor of ATM kinase.


name: RAD52_HUMAN DNA repair protein RAD52 homolog (sprot)

description: A DNA repair protein RAD52 homolog that is encoded in the genome of human.


name: [(2R,3S,4R,5R)-5-[6-(benzylamino)-2-chloropurin-9-yl]-3,4-dihydroxyoxolan-2-yl]methyl phosphono hydrogen phosphate


name: GIPR_MOUSE Gastric inhibitory polypeptide receptor (sprot)

description: A gastric inhibitory polypeptide receptor that is encoded in the genome of mouse.


DIMEBUTIC ACID

A branched-chain fatty acid and metabolite of the lactone prodrug simvastatin, whose sodium salt is potentially useful for the treatment of thalassaemias and haemoglobinopathies.


name: YETS2_HUMAN YEATS domain-containing protein 2 (sprot)

description: A YEATS domain-containing protein 2 that is encoded in the genome of human.


APJ_MOUSE Apelin receptor (sprot)

An apelin receptor that is encoded in the genome of mouse.


name: 4-[6-(5-Methanesulfonyl-2,3-dihydro-indol-1-yl)-pyrimidin-4-ylamino]-piperidine-1-carboxylic acid tert-butyl ester


nuclear fast red

An organic sodium salt that is the monosodium salt of 4-amino-1,3-dihydroxy-9,10-dioxo-9,10-dihydroanthracene-2-sulfonic acid. It forms bright red lakes with calcium and is a useful red nuclear staining lake with aluminum.


name: ERN1_MOUSE Serine/threonine-protein kinase/endoribonuclease IRE1 (sprot)

description: A serine/threonine-protein kinase/endoribonuclease IRE1 that is encoded in the genome of mouse.


name: KDM1B_MOUSE Lysine-specific histone demethylase 1B (sprot)

description: A lysine-specific histone demethylase 2 that is encoded in the genome of mouse.


name: MP2K4_MOUSE Dual specificity mitogen-activated protein kinase kinase 4 (sprot)

description: A dual specificity mitogen-activated protein kinase kinase 4 that is encoded in the genome of mouse.


name: FA20C_HUMAN Extracellular serine/threonine protein kinase FAM20C (sprot)

description: An extracellular serine/threonine protein kinase Fam20C that is encoded in the genome of human.


SALVIGENIN

A trimethoxyflavone that is scutellarein in which the hydroxy groups at positions 4', 6, and 7 are replaced by methoxy groups.


name: ACER3_MOUSE Alkaline ceramidase 3 (sprot)

description: An alkaline ceramidase 3 that is encoded in the genome of mouse.


tiamulin

A carbotricyclic compound that is pleuromutilin in which the hydroxyacetate group is replaced by a 2-{[2-(diethylamino)ethyl]sulfanyl}acetate group. An antibacterial drug, tiamulin is used in veterinary medicine (generally as its hydrogen fumarate salt) for the treatment of swine dysentery caused by Serpulina hyodysenteriae.


MCLN1_HUMAN Mucolipin-1 (sprot)

A mucolipin-1 that is encoded in the genome of human.


MCLN2_HUMAN Mucolipin-2 (sprot)

A mucolipin-2 that is encoded in the genome of human.


olodaterol

A member of the class of benzoxazine that is 6-hydroxy-1,4-benzoxazin-3-one in which the hydrogen at position 4 is replaced by a (1R)-1-hydroxy-2-{[1-(4-methoxyphenyl)-2-methylpropan-2-yl]amino}ethyl group. Used (as its hydrochloride salt) for long-term treatment of airflow obstruction in patients with chronic obstructive pulmonary disease including chronic bronchitis and/or emphysema.


abediterol

A quinolone that is 8-hydroxyquinolin-2(1H)-one which carries a 2-{[6-(2,2-difluoro-2-phenylethoxy)hexyl]amino}-1-hydroxyethyl group at position 5. It is a long acting beta2-adrenoceptor agonist currently in development for the treatment of chronic obstructive pulmonary disease (COPD) and asthma.


name: CALCB_HUMAN Calcitonin gene-related peptide 2 (sprot)

description: A calcitonin gene-related peptide 2 that is encoded in the genome of human.


name: TET3_HUMAN Methylcytosine dioxygenase TET3 (sprot)

description: A methylcytosine dioxygenase TET3 that is encoded in the genome of human.


2-hydroxyglutaric acid

A 2-hydroxydicarboxylic acid that is glutaric acid in which one hydrogen alpha- to a carboxylic acid group is substituted by a hydroxy group.


name: IF2A_HUMAN Eukaryotic translation initiation factor 2 subunit 1 (sprot)

description: A eukaryotic translation initiation factor 2 subunit 1 that is encoded in the genome of human.


IL15_MOUSE Interleukin-15 (sprot)

An interleukin-15 that is encoded in the genome of mouse.


name: JMJD7_HUMAN Bifunctional peptidase and (3S)-lysyl hydroxylase JMJD7 (sprot)

description: A bifunctional peptidase and (3S)-lysyl hydroxylase JMJD7 that is encoded in the genome of human.


name: MENA_MYCTU 1,4-dihydroxy-2-naphthoate octaprenyltransferase (sprot)


name: LONM_HUMAN Lon protease homolog, mitochondrial (sprot)

description: A Lon protease, mitochondrial that is encoded in the genome of human.


name: TRPM5_MOUSE Transient receptor potential cation channel subfamily M member 5 (sprot)

description: A transient receptor potential cation channel subfamily M member 5 that is encoded in the genome of mouse.


name: SRBP1_HUMAN Sterol regulatory element-binding protein 1 (sprot)

description: A sterol regulatory element-binding protein 1 that is encoded in the genome of human.


name: 1-Piperidinecarboxylic acid, 3-(3-(1-carboxy-1-methylethoxy)phenyl)-, 1-((4-(1-methylethyl)phenyl)methyl) ester, (3S)-


name: TRM3_HCMVA Tripartite terminase subunit 3 (sprot)


name: UFO_MOUSE Tyrosine-protein kinase receptor UFO (sprot)

description: A tyrosine-protein kinase receptor UFO that is encoded in the genome of mouse.


name: MERTK_MOUSE Tyrosine-protein kinase Mer (sprot)

description: A tyrosine-protein kinase Mer that is encoded in the genome of mouse.


OXINDOLE

An indolinone carrying an oxo group at position 2.


GARDENIN B

A tetramethoxyflavone that is  tangeretin in which the methoxy group at position 5 has been replaced by a hydroxy group.


D-galactal

A glycal derived from D-galactopyranose


name: CIB1_HUMAN Calcium and integrin-binding protein 1 (sprot)

description: A calcium and integrin-binding protein 1 that is encoded in the genome of human.


name: NSD1_HUMAN Histone-lysine N-methyltransferase, H3 lysine-36 specific (sprot)

description: A histone-lysine N-methyltransferase, H3 lysine-36 specific that is encoded in the genome of human.


2,3-dihydro-3beta-methoxy withaferin A

A withanolide that is 2,3-dihydrowithaferin A substituted by a beta-methoxy group at position 3. It has been isolated from the aerial parts of Physalis longifolia.


name: RORA_MOUSE Nuclear receptor ROR-alpha (sprot)

description: A nuclear receptor ROR-alpha that is encoded in the genome of mouse.


name: MTA70_HUMAN N6-adenosine-methyltransferase catalytic subunit (sprot)

description: An N6-adenosine-methyltransferase catalytic subunit that is encoded in the genome of human.


1-myristoyl-sn-glycerol 3-phosphate

A 1-acyl-sn-glycerol 3-phosphate having myristoyl (tetradecanoyl) as the 1-O-acyl group.


An amino disaccharide consisting of beta-D-galactose linked via a (1->3)-glycosidic bond to N-acetyl-D-glucosamine.


A disaccharide consisting of beta-D-galactose linked via a (1->4)-glycosidic bond to N-acetyl-D-glucosamine.


An amino disaccharide consisting of N-acetyl-D-glucosamine having a beta-D-galactosyl residue attached at the 6-position.


lactose

A glycosylglucose disaccharide, found most notably in milk, that consists of D-galactose and D-glucose fragments bonded through a beta-1->4 glycosidic linkage. The glucose fragment can be in either the alpha- or beta-pyranose form, whereas the galactose fragment can only have the beta-pyranose form.


allolactose

A glycosylglucose consisting of galactose and glucose units linked through a 1-6 glycosidic linkage.


name: PARL_HUMAN Presenilin-associated rhomboid-like protein, mitochondrial (sprot)

description: A presenilin-associated rhomboid-like protein, mitochondrial that is encoded in the genome of human.


name: PLD3_HUMAN 5'-3' exonuclease PLD3 (sprot)

description: A 5'-3' exonuclease PLD3 that is encoded in the genome of human.


name: PLD4_HUMAN 5'-3' exonuclease PLD4 (sprot)

description: A 5'-3' exonuclease PLD4 that is encoded in the genome of human.


name: CANB1_HUMAN Calcineurin subunit B type 1 (sprot)

description: A calcineurin subunit B type 1 that is encoded in the genome of human.


name: 4-[3-(2-Methoxy-pyridin-3-yl)-pyrazolo[1,5-a]pyrimidin-5-yl]-piperazine-1-carboxylic acid isopropyl ester


name: CACB2_HUMAN Voltage-dependent L-type calcium channel subunit beta-2 (sprot)

description: A voltage-dependent L-type calcium channel subunit beta-2 that is encoded in the genome of human.


name: GPR27_HUMAN Probable G-protein coupled receptor 27 (sprot)

description: A probable G-protein coupled receptor 27 that is encoded in the genome of human.


SDC2_HUMAN Syndecan-2 (sprot)

A syndecan-2 that is encoded in the genome of human.


PANX1_MOUSE Pannexin-1 (sprot)

A pannexin-1 that is encoded in the genome of mouse.


name: PRAP1_HUMAN Proline-rich acidic protein 1 (sprot)

description: A proline-rich acidic protein 1 that is encoded in the genome of human.


ASCOCHLORIN

A dihydroxybenzaldehyde that is 2,4-dihydroxybenzaldehyde which is substituted by a (1E,3E)-3-methyl-1-[(1R,2R,6R)-1,2,6-trimethyl-3-oxocyclohexyl]penta-1,3-dien-5-yl group at position 3, chlorine at position 5, and a methyl group at position 6. A meroterpenoid produced by several fungi including Ascochyta viciae . It exhibits anticancer, antifungal and antiprotozoal activities.


ascofuranol

A dihydroxybenzaldehyde that is 2,4-dihydroxybenzaldehyde which is substituted by a {(2E,6E)-7-[(2S,4S)-4-hydroxy-5,5-dimethyltetrahydrofuran-2-yl]-3-methylocta-2,6-dien-1-yl} group at position 3, chlorine at position 5, and a methyl group at position 6. A meroterpenoid produced by various filamentous fungi, including Acremonium egyptiacum.


name: DPTOR_HUMAN DEP domain-containing mTOR-interacting protein (sprot)

description: A DEP domain-containing mTOR-interacting protein that is encoded in the genome of human.


A member of the class of pyrazoles that is 1H-pyrazole substituted by 2-fluoro-6-(trifluoromethyl)benzyl and (2,6-difluorobenzoyl)amino groups at positions 1 and 3, respectively. It is a inhibitor of Ca(2+) release-activated Ca(2+) (CRAC) channel and inhibits the release of mast cell mediators and T-cell cytokines in human and rat preparations.


ORAI3_HUMAN Protein orai-3 (sprot)

A protein orai-3 that is encoded in the genome of human.


ORAI2_HUMAN Protein orai-2 (sprot)

A protein orai-2 that is encoded in the genome of human.


name: IAPP_HUMAN Islet amyloid polypeptide (sprot)

description: An islet amyloid polypeptide that is encoded in the genome of human.


PYRROLOQUINOLINE QUINONE

A pyrroloquinoline having oxo groups at the 4- and 5-positions and carboxy groups at the 2-, 7- and 9-positions.


name: ATS5_MOUSE A disintegrin and metalloproteinase with thrombospondin motifs 5 (sprot)

description: An a disintegrin and metalloproteinase with thrombospondin motifs 5 that is encoded in the genome of mouse.


CBPB2_RAT Carboxypeptidase B2 (sprot)

A carboxypeptidase B2 that is encoded in the genome of rat.


name: MLP3A_HUMAN Microtubule-associated proteins 1A/1B light chain 3A (sprot)

description: A microtubule-associated proteins 1A/1B light chain 3A that is encoded in the genome of human.


name: TRPM1_MOUSE Transient receptor potential cation channel subfamily M member 1 (sprot)

description: A transient receptor potential cation channel subfamily M member 1 that is encoded in the genome of mouse.


PHENYL PROPIONIC ACID

A monocarboxylic acid that is propionic acid substituted at position 3 by a phenyl group.


name: LV657_HUMAN Immunoglobulin lambda variable 6-57 (sprot)

description: A protein that is a translation product of the IGLV6-57 gene in human.


A diterpene derived from pimarane by dehydrogenation across the  C(8)-C(14) and C(15)-C(16) bonds


name: GNMT_HUMAN Glycine N-methyltransferase (sprot)

description: A glycine N-methyltransferase that is encoded in the genome of human.


L-arginine hydroxamate

An arginine derivative obtained by formal condensation of the carboxy group of L-arginine with the amino group of hydroxylamine.


name: PG057_VACCW Envelope phospholipase OPG057 (sprot)


name: PSA1_HUMAN Proteasome subunit alpha type-1 (sprot)

description: A proteasome subunit alpha type-1 that is encoded in the genome of human.


name: PSB4_HUMAN Proteasome subunit beta type-4 (sprot)

description: A proteasome subunit beta type-4 that is encoded in the genome of human.


name: A1ATR_HUMAN Alpha-1-antitrypsin-related protein (sprot)

description: A protein that is a translation product of the SERPINA2 gene in human.


name: HEXA_BOVIN Beta-hexosaminidase subunit alpha (sprot)

description: A beta-hexosaminidase subunit alpha that is encoded in the genome of cow.


name: DEGPL_CHLTR Probable periplasmic serine endoprotease DegP-like (sprot)


name: TNI3K_MOUSE Serine/threonine-protein kinase TNNI3K (sprot)

description: A serine/threonine-protein kinase TNNI3K that is encoded in the genome of mouse.


METHYLBREVIFOLIN CARBOXYLATE

An organic heterotricyclic compound that is 1,2,3,5-tetrahydrocyclopenta[c]isochromene substituted by hydroxy groups at positions 7, 8 and 9, oxo groups at positions 3 and 5 and a methoxycarbonyl group at position 1. Isolated from  Phyllanthus urinaria and Phyllanthus niruri, it exhibits vasorelaxant activity.


name: UHRF1_HUMAN E3 ubiquitin-protein ligase UHRF1 (sprot)

description: An E3 ubiquitin-protein ligase UHRF1 that is encoded in the genome of human.


name: MK08_MOUSE Mitogen-activated protein kinase 8 (sprot)

description: A mitogen-activated protein kinase 8 that is encoded in the genome of mouse.


An oxime O-ether that is the (E)-O-(2-aminoethyl)oxime derived from 4'-iodo-5-methoxyvalerophenone.


name: PAR4_MOUSE Proteinase-activated receptor 4 (sprot)

description: A proteinase-activated receptor 4 that is encoded in the genome of mouse.


name: HAVR2_HUMAN Hepatitis A virus cellular receptor 2 (sprot)

description: A hepatitis A virus cellular receptor 2 that is encoded in the genome of human.


name: MGAT2_RAT Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (sprot)

description: An alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase that is encoded in the genome of rat.


STC1_HUMAN Stanniocalcin-1 (sprot)

A stanniocalcin-1 that is encoded in the genome of human.


STC1_MOUSE Stanniocalcin-1 (sprot)

A stanniocalcin-1 that is encoded in the genome of mouse.


name: SQOR_HUMAN Sulfide:quinone oxidoreductase, mitochondrial (sprot)

description: A sulfide:quinone oxidoreductase, mitochondrial that is encoded in the genome of human.


name: CLC4M_HUMAN C-type lectin domain family 4 member M (sprot)

description: A C-type lectin domain family 4 member M that is encoded in the genome of human.


alpha-L-fucose

An L-fucopyranose having alpha-configuration at the anomeric centre.


name: NAA40_HUMAN N-alpha-acetyltransferase 40 (sprot)

description: An N-alpha-acetyltransferase 40 that is encoded in the genome of human.


MFN2_HUMAN Mitofusin-2 (sprot)

A mitofusin-2 that is encoded in the genome of human.


name: MDR3_HUMAN Phosphatidylcholine translocator ABCB4 (sprot)

description: A phosphatidylcholine translocator ABCB4 that is encoded in the genome of human.


D-synephrine

The D-enantiomer of synephrine.


ulotaront

A member of the class of thienopyrans that is 4,7-dihydro-5H-thieno[2,3-c]pyran substituted by a (methylamino)methyl at position 7S. It is a trace amine-associated receptor 1 and serotonin 5-HT1A receptors agonist that has demonstrated efficacy in the treatment of patients with schizophrenia.


METHYL ANTHRANILATE

A benzoate ester that is the methyl ester of anthranilic acid.


name: 2-Amino-5-(tetrahydro-furan-2-yl)-4-trifluoromethyl-benzoic acid methyl ester


SALUTARIDINE

A morphinane alkaloid from the opium poppy, in which the 5,6,8,14-tetradehydromorphinan-7-one skeleton is substituted at position 4 by a hydroxyl group, positions 3 and 6 by methoxy groups and position N17 by a methyl group. An intermediate in the biosynthesis of narcotic analgesics such as morphine and codeine.


name: Adenosine, [P(R)]-5'-O-[(S)-hydroxymercaptophosphinyl]-P-thioadenylyl-(3'-->5')-, cyclic (2'-->5')-nucleotide


name: 4H-Cyclopenta(b)thiophene-3-carboxylic acid, 5,6-dihydro-2-(((phenylamino)thioxomethyl)amino)-, ethyl ester


name: CGAS_MOUSE Cyclic GMP-AMP synthase (sprot)

description: A protein MB21D1 that is encoded in the genome of mouse.


name: LRRK2_MOUSE Leucine-rich repeat serine/threonine-protein kinase 2 (sprot)

description: A leucine-rich repeat serine/threonine-protein kinase 2 that is encoded in the genome of mouse.


A hydroxypiperidine that is duvoglustat in which the amino hydrogen is replaced by an ethyl group. It is an inhibitor of alpha-glucosidase, an agonist of the glucose sensor SGLT3 and exhibits anti-HIV activity.


name: NPFF2_MOUSE Neuropeptide FF receptor 2 (sprot)

description: A neuropeptide FF receptor 2 that is encoded in the genome of mouse.


name: PRRP_HUMAN Prolactin-releasing peptide (sprot)

description: A prolactin-releasing peptide that is encoded in the genome of human.


BUFALIN

A 14beta-hydroxy steroid that is bufan-20,22-dienolide having hydroxy substituents at the 5beta- and 14beta-positions. It has been isolated from the skin of the toad Bufo bufo.


name: Protease-Activated Receptor-1 antagonist 1


name: Protease-Activated Receptor-1 antagonist 3


A member of the class of aminopyrimidines that is pyrimidine in which the hydrogens at positions 2, 4 and 5 have been replaced by [3-methyl-1-(2,2,2-trifluoroethyl)-1H-pyrazol-4-yl]nitrilo, {3-[(cyclobutylcarbonyl)amino]propyl}nitrilo, and cyclopropyl groups, respectively.


eletriptan

An N-alkylpyrrolidine, that is N-methylpyrrolidine in which the pro-R hydrogen at position 2 is replaced by a {5-[2-(phenylsulfonyl)ethyl]-1H-indol-3-yl}methyl group.


VNN1_MOUSE Pantetheinase (sprot)

A pantetheinase that is encoded in the genome of mouse.


BTD_HUMAN Biotinidase (sprot)

A biotinidase that is encoded in the genome of human.


name: SHIP2_MOUSE Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 (sprot)

description: A phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 that is encoded in the genome of mouse.


BECN1_HUMAN Beclin-1 (sprot)

A beclin-1 that is encoded in the genome of human.


bilirubin XIIIalpha

A biladiene that is a linear tetrapyrrole and a regioisomer of bilirubin IXalpha, in which the dipyrroles are of endovinyl type only.


name: C5AR1_MOUSE C5a anaphylatoxin chemotactic receptor 1 (sprot)

description: A C5a anaphylatoxin chemotactic receptor 1 that is encoded in the genome of mouse.


narlaprevir

An azabicyclohexane that is (1R,5S)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane substituted by [(3S)-1-(cyclopropylamino)-1,2-dioxoheptan-3-yl]aminoacyl and N-({1-[(tert-butylsulfonyl)methyl]cyclohexyl}carbamoyl)-3-methyl-L-valyl groups at positions 2S and 3, respectively. It is a hepatitis C virus (HCV) NS3/4A serine protease inhibitor (Ki = 6 nM) that is used for the treatment of chronic hepatitis C.


PECTOLINARIN

A disaccharide derivative that consists of  pectolinarigenin substituted by a 6-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyl moiety at position 7 via a glycosidic linkage.


RHOIFOLIN

An apigenin derivative having an alpha-(1->2)-L-rhamnopyranosyl)-beta-D-glucopyranosyl moiety attached to the 7-hydroxy group.


name: TRPV2_HUMAN Transient receptor potential cation channel subfamily V member 2 (sprot)

description: A transient receptor potential cation channel TRPV2 that is encoded in the genome of human.


INHA_HUMAN Inhibin alpha chain (sprot)

An inhibin alpha chain that is encoded in the genome of human.


name: STING_RAT Stimulator of interferon genes protein (sprot)

description: A transmembrane protein 173 that is encoded in the genome of rat.


name: VISTA_HUMAN V-type immunoglobulin domain-containing suppressor of T-cell activation (sprot)

description: A V-type immunoglobulin domain-containing suppressor of T-cell activation that is encoded in the genome of human.


salvianolic acid B

A member of the class of 1-benzofurans that is an antioxidant and free radical scavenging compound extracted from S. miltiorrhiza


name: PTN11_MOUSE Tyrosine-protein phosphatase non-receptor type 11 (sprot)

description: A tyrosine-protein phosphatase non-receptor type 11 that is encoded in the genome of mouse.


pyrvinium

A quinolinium ion that is 1-methylquinolinium substituted by dimethylamino group at position 6 and a (E)-2-(2,5-dimethyl-1-phenyl-1H-pyrrol-3-yl)ethenyl at position 2. It is a  anthelminthic drug active against pinworms. The salts of pyrvinium can also be used as anticancer agents.


name: MK07_MOUSE Mitogen-activated protein kinase 7 (sprot)

description: A mitogen-activated protein kinase 7 that is encoded in the genome of mouse.


name: GEMI4_HUMAN Gem-associated protein 4 (sprot)

description: A gem-associated protein 4 that is encoded in the genome of human.


ganciclovir

An oxopurine that is  guanine substituted by a [(1,3-dihydroxypropan-2-yl)oxy]methyl group at position 9. Ganciclovir is an antiviral drug used to treat or prevent AIDS-related cytomegalovirus infections.


SPAST_DROME Spastin (sprot)

A spastin that is encoded in the genome of fruit fly.


name: IF4G2_MOUSE Eukaryotic translation initiation factor 4 gamma 2 (sprot)

description: A eukaryotic translation initiation factor 4 gamma 2 that is encoded in the genome of mouse.


SPAST_HUMAN Spastin (sprot)

A spastin that is encoded in the genome of human.


ARSA_HUMAN Arylsulfatase A (sprot)

An arylsulfatase A that is encoded in the genome of human.


name: EMAL4_HUMAN Echinoderm microtubule-associated protein-like 4 (sprot)

description: An echinoderm microtubule-associated protein-like 4 that is encoded in the genome of human.


name: L1CAM_HUMAN Neural cell adhesion molecule L1 (sprot)

description: A neural cell adhesion molecule L1 that is encoded in the genome of human.


GALK1_MOUSE Galactokinase (sprot)

A galactokinase that is encoded in the genome of mouse.


name: DGAT2_RAT Diacylglycerol O-acyltransferase 2 (sprot)

description: A diacylglycerol O-acyltransferase 2 that is encoded in the genome of rat.


SQSTM_HUMAN Sequestosome-1 (sprot)

A sequestosome-1 that is encoded in the genome of human.


name: RN168_HUMAN E3 ubiquitin-protein ligase RNF168 (sprot)

description: An E3 ubiquitin-protein ligase RNF168 that is encoded in the genome of human.


CP1A2_MOUSE Cytochrome P450 1A2 (sprot)

A cytochrome P450 1A2 that is encoded in the genome of mouse.


name: 1h-pyrazole-3,4-dicarboxylic Acid, 1-(3,4-dimethylphenyl)-5-phenyl-, Diethyl Ester


The R-enantiomer of etodolac. It is inactive, in contrast to the enantiomer, (S)-etodolac, which is a preferential inhibitor of cyclo-oxygenase 2 and a non-steroidal anti-inflammatory. The racemate is commonly used for the treatment of rheumatoid arthritis and osteoarthritis, and for the alleviation of postoperative pain.


prasugrel

A racemate comprising equal amounts of (R)- and (S)-prasugrel. Used (as its hydrochloride salt) to prevent blood clots in people with acute coronary syndrome who are undergoing a procedure after a recent heart attack or stroke, and in people with certain disorders of the heart or blood vessels.


name: SRSF6_HUMAN Serine/arginine-rich splicing factor 6 (sprot)

description: A serine/arginine-rich splicing factor 6 that is encoded in the genome of human.


name: PDC_ZYMMO Pyruvate decarboxylase (sprot)

description: A protein that is a translation product of the pdc gene in Zymomonas mobilis subsp. mobilis ZM4.


name: 2-[1-[(4-Amino-2-methylpyrimidin-5-yl)methyl]triazol-4-yl]ethyl phosphono hydrogen phosphate


name: GID4_HUMAN Glucose-induced degradation protein 4 homolog (sprot)

description: A glucose-induced degradation protein 4 homolog that is encoded in the genome of human.


name: PARK7_HUMAN Parkinson disease protein 7 (sprot)

description: A parkinson disease protein 7 that is encoded in the genome of human.


name: 1-[5-(5-chloro-thiophen-2-yl)-isoxazol-3-yl methyl]-1H-pyrrole-2-carboxylic acid (1-isopropyl-piperidin-4-yl)-amide


name: CALL3_HUMAN Calmodulin-like protein 3 (sprot)

description: A calmodulin-like protein 3 that is encoded in the genome of human.


name: LPQY_MYCTU Trehalose-binding lipoprotein LpqY (sprot)


TREHALOSE

A trehalose in which both glucose residues have alpha-configuration at the anomeric carbon.


name: PHP14_HUMAN 14 kDa phosphohistidine phosphatase (sprot)

description: A 14 kDa phosphohistidine phosphatase that is encoded in the genome of human.


name: 6PGD_RAT 6-phosphogluconate dehydrogenase, decarboxylating (sprot)

description: A 6-phosphogluconate dehydrogenase, decarboxylating that is encoded in the genome of rat.


name: G6PD_RAT Glucose-6-phosphate 1-dehydrogenase (sprot)

description: A glucose-6-phosphate 1-dehydrogenase that is encoded in the genome of rat.


name: GSHR_RAT Glutathione reductase (Fragment) (sprot)


A member of the class of anthraquinone that is 1,4-diamino-9,10-anthraquinone in which the two amino groups are carrying 3-(diethylamino)-2-hydroxypropyl and (oxiran-2-yl)methyl substituents. It exhibits anti-cancer properties.


name: BCR_MOUSE Breakpoint cluster region protein (sprot)

description: A breakpoint cluster region protein that is encoded in the genome of mouse.


IDUA_HUMAN Alpha-L-iduronidase (sprot)

An alpha-L-iduronidase that is encoded in the genome of human.


name: VSIG8_HUMAN V-set and immunoglobulin domain-containing protein 8 (sprot)

description: A V-set and immunoglobulin domain-containing protein 8 that is encoded in the genome of human.


apilimod

Apilimod (STA 5326) is a potent IL-12/IL-23 inhibitor, and strongly inhibits IL-12 in IFNg/SAC-stimulated human PBMCs and SAC-treated monkey PBMCs. Apilimod is a potent and highly selective PIKfyve inhibitor.


An indolyl pyrimidinamine compound resulting from the Sonogashira coupling of 10-bromo-6,7-dihydro-5H-pyrimido[5,4-c]carbazol-2-amine with 2-methylbut-3-yn-2-ol.


name: DPOLQ_HUMAN DNA polymerase theta (sprot)

description: A DNA polymerase theta that is encoded in the genome of human.


name: CDKL4_HUMAN Cyclin-dependent kinase-like 4 (sprot)

description: A cyclin-dependent kinase-like 4 that is encoded in the genome of human.


A member of the class of pyrazoles that is 1-(2,6-dichlorophenyl)-1H-pyrazole which is substituted by a difluoromethyl group at position 3 and by a 2-(isobutyrylamino)-1,3-thiazol-5-yl group at position 5. It is a a potent cell-permeable inhibitor of LIM kinase 1 and 2.


A beta-D-galactopyranoside having a 4-nitrophenyl substituent at the anomeric position.


name: OTUB1_HUMAN Ubiquitin thioesterase OTUB1 (sprot)

description: A ubiquitin thioesterase OTUB1 that is encoded in the genome of human.


name: UBP36_HUMAN Ubiquitin carboxyl-terminal hydrolase 36 (sprot)

description: A ubiquitin carboxyl-terminal hydrolase 36 that is encoded in the genome of human.


name: 1-benzyl-1 H-pyrazole-4-carboxylic acid 4-carbamimidoyl-benzylamide


A member of the class of 1,3-benzoxazoles that is 1,3-benzoxazole substituted at positions 2 and 5 by 4-ethylphenyl and 3-nitrobenzamido groups respectively.


name: BAK_HUMAN Bcl-2 homologous antagonist/killer (sprot)

description: A Bcl-2 homologous antagonist/killer that is encoded in the genome of human.


name: PG12A_HUMAN Group XIIA secretory phospholipase A2 (sprot)

description: A group XIIA secretory phospholipase A2 that is encoded in the genome of human.


RUBIARBONONE C

A pentacyclic triterpenoid of the class of arborinane-type terpenoids isolated from the roots of Rubia yunnanensis.


name: ALKB2_HUMAN DNA oxidative demethylase ALKBH2 (sprot)

description: A DNA oxidative demethylase ALKBH2 that is encoded in the genome of human.


name: (S)-2-dibenzylamino-3-(4-hydroxyphenyl)propionic acid methyl ester


name: GLF1_KLEPN UDP-galactopyranose mutase (sprot)


mephenytoin

An imidazolidine-2,4-dione (hydantoin) in which the imidazolidine nucleus carries a methyl group at N-3 and has ethyl and phenyl substituents at C-5. An anticonvulsant, it is no longer available in the USA or the UK but is still studied largely because of its interesting hydroxylation polymorphism.


CP3A2_RAT Cytochrome P450 3A2 (sprot)

A protein that is a translation product of the Cyp3a2 gene in rat.


CP2C6_RAT Cytochrome P450 2C6 (sprot)

A protein that is a translation product of the Cyp2c6 gene in rat.


name: NDKM_HUMAN Nucleoside diphosphate kinase, mitochondrial (sprot)

description: A nucleoside diphosphate kinase, mitochondrial that is encoded in the genome of human.


name: GCDH_HUMAN Glutaryl-CoA dehydrogenase, mitochondrial (sprot)

description: A glutaryl-CoA dehydrogenase, mitochondrial that is encoded in the genome of human.


name: PDCD1_MOUSE Programmed cell death protein 1 (sprot)

description: A programmed cell death protein 1 that is encoded in the genome of mouse.


A secondary amino compound that is 4-(2-aminoethyl)-2,5-dimethoxybenzonitrile in which one of the hydrogens of the amino group has been replaced by a 2-hydroxybenzyl group. A 5-hydroxytryptamine 2A receptor agonist.


name: GHRL_BOVIN Appetite-regulating hormone (sprot)


ceralasertib

Ceralasertib is an orally available morpholino-pyrimidine-based inhibitor of ataxia telangiectasia and rad3 related (ATR) kinase, with potential antineoplastic activity. Upon oral administration, Ceralasertib selectively inhibits ATR activity by blocking the downstream phosphorylation of the serine/threonine protein kinase CHK1. This prevents ATR-mediated signaling, and results in the inhibition of DNA damage checkpoint activation, disruption of DNA damage repair, and the induction of tumor cell apoptosis.


name: NEUL_RAT Neurolysin, mitochondrial (sprot)

description: A neurolysin, mitochondrial that is encoded in the genome of rat.


IL1B_MOUSE Interleukin-1 beta (sprot)

An interleukin-1 beta that is encoded in the genome of mouse.


name: NPT2B_RAT Sodium-dependent phosphate transport protein 2B (sprot)

description: A sodium-dependent phosphate transport protein 2B that is encoded in the genome of rat.


name: PSD10_HUMAN 26S proteasome non-ATPase regulatory subunit 10 (sprot)

description: A 26S proteasome non-ATPase regulatory subunit 10 that is encoded in the genome of human.


name: MED25_HUMAN Mediator of RNA polymerase II transcription subunit 25 (sprot)

description: A mediator of RNA polymerase II transcription subunit 25 that is encoded in the genome of human.


HEPC_HUMAN Hepcidin (sprot)

A hepcidin that is encoded in the genome of human.


SEPANTRONIUM

An organic cation that is 1-(2-methoxyethyl)-2-methyl-1H-naphtho[2,3-d]imidazole-4,9-dione in which the nitrogen at position 3 of the napthoimidazole moiety has been alkylated by a pyrazin-2-ylmethyl group.


name: [[(2R,3S,4R,5R)-5-(6-anilinopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate


name: [[(2R,3S,4R,5R)-3,4-dihydroxy-5-(8-oxo-7H-purin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate


name: CXXC4_HUMAN CXXC-type zinc finger protein 4 (sprot)

description: A CXXC-type zinc finger protein 4 that is encoded in the genome of human.


name: FXL19_HUMAN F-box/LRR-repeat protein 19 (sprot)

description: An F-box/LRR-repeat protein 19 that is encoded in the genome of human.


name: CXXC5_HUMAN CXXC-type zinc finger protein 5 (sprot)

description: A CXXC-type zinc finger protein 5 that is encoded in the genome of human.


A member of the class of prostaglandins J that consists of prosta-5,9,13-trien-1-oic acid substituted by an oxo group at position 11 and a hydroxy group at position 15 (the 5Z,13E,15S stereoisomer).


pirtobrutinib

A secondary carboxamide resulting from the formal condensation of the carboxy group of 5-fluoro-2-methoxybenzoic acid with the amino group of 5-amino-3-[4-(aminomethyl)phenyl]-1-[(2S)-1,1,1-trifluoropropan-2-yl]-1H-pyrazole-4-carboxamide. It is a BTK inhibitor used for the treatment of adult patients with chronic lymphocytic leukemia or small lymphocytic lymphoma.


FA10_MOUSE Coagulation factor X (sprot)

A coagulation factor X that is encoded in the genome of mouse.


(2R)-3-(3,4-dihydroxyphenyl)lactic acid

A (2R)-2-hydroxy monocarboxylic acid that is (R)-lactic acid substituted at position 3 by a 3,4-dihydroxyphenyl group.


A member of the class of 1,3-thiazoles that is 1,3-thiazole substituted by (2E)-2-(2-carboxybenzylidene)hydrazinyl and 2-chlorophenyl groups at positions 2 and 4, respectively. It is a potent inhibitor of human dihydroorotate dehydrogenase (hDHODH) with IC50 of 32 nM. It exhibits antineoplastic activity and broad-spectrum antiviral activity against various RNA viruses including influenza A, Zika, Ebola, and SARS-CoV-2 viruses.


loganetin

An iridoid monoterpenoid that is methyl (4aS,7aR)-1,4a,5,6,7,7a-hexahydrocyclopenta[c]pyran-4-carboxylate substituted at positions 1 and 6 by hydroxy groups and at postion 7 by a methyl group; the aglycone of loganin.


A galloyl-beta-D-glucose compound having four galloyl groups in the 1-, 2-, 3- and 6-positions.


name: PAX3_HUMAN Paired box protein Pax-3 (sprot)

description: A paired box protein Pax-3 that is encoded in the genome of human.


N-desmethylenzalutamide

A benzamide obtained by formal condensation of the carboxy group of 4-{3-[4-cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl}-2-fluorobenzoic acid with ammonia.


ISAVUCONAZOLE

A 1,3-thiazole that is butan-2-ol which is substituted at positions 1, 2, and 3 by 1,2,4-triazol-1-yl, 2,5-difluorophenyl, and 4-(p-cyanophenyl)-1,3-thiazol-2-yl groups, respectively. It is an antifungal drug used for the treatment of invasive aspergillosis and invasive mucormycosis.


MICAFUNGIN

A cyclic hexapeptide echinocandin antibiotic which exerts its effect by inhibiting the synthesis of 1,3-beta-D-glucan, an integral component of the fungal cell wall. It is used as the sodium salt for the treatment of invasive candidiasis, and of aspergillosis in patients who are intolerant of other therapy.


A dihydroxyflavone that is  chrysin substituted by a prenyl group at position 6.


A benzodioxole consisting of a benzene ring substituted by a the methylenedioxy group.


name: ODP2_HUMAN Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial (sprot)

description: A dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial that is encoded in the genome of human.


name: HBA_HUMAN Hemoglobin subunit alpha (sprot)

description: A hemoglobin subunit alpha that is encoded in the genome of human.


name: HBB_HUMAN Hemoglobin subunit beta (sprot)

description: A hemoglobin subunit beta that is encoded in the genome of human.


methoxyphenamine

An amphetamine methylated on nitrogen and with the phenyl ring methoxylated at C-2. A beta-adrenergic receptor agonist, it is used as a bronchodilator.


isosilybin

A flavonolignan isolated from Silybum marianum.


name: ZDH20_HUMAN Palmitoyltransferase ZDHHC20 (sprot)

description: A palmitoyltransferase ZDHHC20 that is encoded in the genome of human.


name: ZDHC2_HUMAN Palmitoyltransferase ZDHHC2 (sprot)

description: A palmitoyltransferase ZDHHC2 that is encoded in the genome of human.


decarbamoylsaxitoxin

A pyrrolopurine that is 2,6-diiminodecahydropyrrolo[1,2-c]purine carrying an additional hydroxymethyl substituent at position 4 as well as two hydroxy substituents at position 10. A toxin that is isolated from marine dinoflagellates and cyanobacteria and is known to cause paralytic shellfish poisoning.


name: MYB_HUMAN Transcriptional activator Myb (sprot)

description: A myb proto-oncogene protein that is encoded in the genome of human.


name: MAPK2_PNECA Mitogen-activated protein kinase 2 (sprot)


ESCULIN

A hydroxycoumarin that is the 6-O-beta-D-glucoside of esculetin.


(S,R,R,R)-nebivolol

A 2,2'-iminobis[1-(6-fluoro-3,4-dihydro-2H-chromen-2-yl)ethanol] that has (1R,1'R,2R,2'S)-configuration.


A leukotriene that is (5S,7E,9E,11Z,14Z)-5-hydroxyicosa-7,9,11,14-tetraenoic acid in which a glutathionyl group is attached at position 6 via a sulfide linkage.


name: CSRA_ECOLI Carbon storage regulator (sprot)

description: A carbon storage regulator that is encoded in the genome of Escherichia coli K-12.


name: RSMA_PSEAE Ribosomal RNA small subunit methyltransferase A (sprot)


ibogamine

A monoterpenoid indole alkaloid with formula C19H24N2. It is isolated from the flowering plant genus, Tabernaemontana and exhibits anti-addictive properties.


name: ACHA7_CHICK Neuronal acetylcholine receptor subunit alpha-7 (sprot)

description: A neuronal acetylcholine receptor subunit alpha-7 that is encoded in the genome of chicken.


name: TRDMT_HUMAN tRNA (cytosine(38)-C(5))-methyltransferase (sprot)

description: A tRNA (cytosine-5-)-methyltransferase that is encoded in the genome of human.


FOSFRUCTOSE

A D-fructofuranose 1,6-bisphosphate with a beta-configuration at the anomeric position.


primuline (acid form)

A member of the class of benzothiazoles that is 2,6'-bi-1,3-benzothiazole substituted at positions 2' 6 and 7 by 4-aminophenyl, methyl and sulfo groups respectively. The monosodium salt is the biological dye 'primuline'.


name: DPRE1_MYCS2 Decaprenylphosphoryl-beta-D-ribose oxidase (sprot)


A secondary carboxamide resulting from the formal condensation of the carboxy group of 1-[1-(naphthalen-1-yl)ethyl]piperidine-4-carboxylic acid with the amino group of 1-(2-methoxypyridin-4-yl)methanamine. It is a SARS-CoV-2 papain-like protease (PLpro) inhibitor.


aloin A

A C-glycosyl compound that is beta-D-glucopyranose in which the anomeric hydroxy group is replaced by a 4,5-dihydroxy-2-(hydroxymethyl)-10-oxo-9,10-dihydroanthracen-9-yl moiety (the 9S diastereoisomer).


name: K1KB5_MOUSE Kallikrein 1-related peptidase b5 (sprot)

description: A kallikrein 1-related peptidase b5 that is encoded in the genome of mouse.


name: 4-Oxazolecarboxylic acid, 2-(4-chlorophenyl)-5-methyl-, ethyl ester


RAFFINOSE

A trisaccharide composed of alpha-D-galactopyranose, alpha-D-glucopyranose and beta-D-fructofuranose joined in sequence by 1->6 and 1<->2 glycosidic linkages, respectively.


A member of the class of  triazoles that is 1-phenyl-1H-1,2,4-triazole substituted by 2-hydroxyphenyl groups at positions 3 and 5.


withaferin A

A  withanolide that is 5,6:22,26-diepoxyergosta-2,24-diene-1,26-dione substituted by hydroxy groups at positions 4 and 27 (the 4beta,5beta,6beta,22R stereoisomer). Isolated from Physalis longifolia, it exhibits cytotoxic activity.


name: ERG1_CANAL Squalene epoxidase ERG1 (sprot)

description: A squalene monooxygenase that is encoded in the genome of Candida albicans SC5314.


ANTHRARUFIN

A  dihydroxyanthraquinone that is anthracene-9,10-dione substituted by hydroxy groups at positions 1 and 5.


ANTHRONE

A member of the class of anthracenes that is  9,10-dihydroanthracene carrying an oxo group at C-9.


dantron

A dihydroxyanthraquinone that is anthracene-9,10-dione substituted by hydroxy groups at positions 1 and 8.


QUINIZARIN

A dihydroxyanthraquinone having the two hydroxy substituents at the 1- and 4-positions; formally derived from anthraquinone by replacement of two hydrogen atoms by hydroxy groups


name: PI51B_HUMAN Phosphatidylinositol 4-phosphate 5-kinase type-1 beta (sprot)

description: A phosphatidylinositol 4-phosphate 5-kinase type-1 beta that is encoded in the genome of human.


name: THIL_HUMAN Acetyl-CoA acetyltransferase, mitochondrial (sprot)

description: An acetyl-CoA acetyltransferase, mitochondrial that is encoded in the genome of human.


name: CDK5_BOVIN Cyclin-dependent kinase 5 (sprot)


RUVB2_HUMAN RuvB-like 2 (sprot)

A RuvB-like 2 that is encoded in the genome of human.


A member of the class of  thiadiazoles  that is 1,3,4-thiadiazole substituted by pyrazin-2-yl and (2,6-dichlorobenzyl)sulfanediyl groups at positions 2 and 5, respectively. It is a selective activator of mechanosensitive channel piezo1.


name: PIEZ1_MOUSE Piezo-type mechanosensitive ion channel component 1 (sprot)

description: A piezo-type mechanosensitive ion channel component 1 that is encoded in the genome of mouse.


name: PIEZ1_HUMAN Piezo-type mechanosensitive ion channel component 1 (sprot)

description: A piezo-type mechanosensitive ion channel component 1 that is encoded in the genome of human.


vanillin acetate

A phenyl acetate obtained by the formal condensation of phenolic group of vanillin with acetic acid.


A quinolone that is 4-quinolone substituted at positions 1, 3, 5, 6 and 7 by ethyl, carboxy, amino, fluorine, and cyclohexylamino groups, respectively. It can directly bind to and block the transcription activity of the active forkhead box protein O1 (Foxo1), but not the Ser256-phosphorylated form. It induces cell death and growth arrest in Burkitt lymphoma cell lines at low concentrations.


name: AAKB1_RAT 5'-AMP-activated protein kinase subunit beta-1 (sprot)

description: A 5'-AMP-activated protein kinase subunit beta-1 that is encoded in the genome of rat.


name: FXR2_HUMAN RNA-binding protein FXR2 (sprot)

description: An RNA-binding protein FXR2 that is encoded in the genome of human.


name: PKNG_MYCTU Serine/threonine-protein kinase PknG (sprot)

description: A protein that is a translation product of the pknG gene in Mycobacterium tuberculosis H37Rv.


name: CD38_RAT ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 (sprot)

description: An ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 that is encoded in the genome of rat.


name: SPA3N_MOUSE Serine protease inhibitor A3N (sprot)

description: A serine protease inhibitor A3N that is encoded in the genome of mouse.


name: TNR9_HUMAN Tumor necrosis factor receptor superfamily member 9 (sprot)

description: A tumor necrosis factor receptor superfamily member 9 that is encoded in the genome of human.


NECT4_HUMAN Nectin-4 (sprot)

A nectin-4 that is encoded in the genome of human.


name: AGT1_HUMAN Alanine--glyoxylate aminotransferase (sprot)

description: An alanine--glyoxylate aminotransferase that is encoded in the genome of human.


(-)-englerin A

A guaiane sesquiterpenoid that is isolated from the bark of Phyllanthus engleri, a plant native to Tanzania and Zimbabwe. It acts as a potent and specific inhibitor of renal cancer cell growth.


name: YTDC1_HUMAN YTH domain-containing protein 1 (sprot)

description: A YTH domain-containing protein 1 that is encoded in the genome of human.


name: YTHD3_HUMAN YTH domain-containing family protein 3 (sprot)

description: A YTH domain-containing family protein 3 that is encoded in the genome of human.


PLATENCIN

A monocarboxylic acid amide obtained by the formal condensation of the amino group of 3-amino-2,4-dihydroxybenzoic acid with the carboxy group of the polycyclic cage component. It is an antibiotic isolated from Streptomyces platensis and exhibits inhibitory activity against fatty acid synthase.


name: PA2GC_MOUSE Group IIC secretory phospholipase A2 (sprot)

description: A group IIC secretory phospholipase A2 that is encoded in the genome of mouse.


name: KCNQ3_RAT Potassium voltage-gated channel subfamily KQT member 3 (sprot)

description: A voltage-gated potassium channel subunit KCNQ3 that is encoded in the genome of rat.


name: PSB6_HUMAN Proteasome subunit beta type-6 (sprot)

description: A proteasome subunit beta type-6 that is encoded in the genome of human.


name: GP174_MOUSE Probable G-protein coupled receptor 174 (sprot)

description: A probable G-protein coupled receptor 174 that is encoded in the genome of mouse.


name: 2-acetamidoethyl [(2R)-2-hydroxy-3-[3-(3-undecoxyphenyl)propanoylamino]propyl] hydrogen phosphate


name: SLTM_HUMAN SAFB-like transcription modulator (sprot)

description: A SAFB-like transcription modulator that is encoded in the genome of human.


name: PARP9_HUMAN Protein mono-ADP-ribosyltransferase PARP9 (sprot)

description: A protein mono-ADP-ribosyltransferase PARP9 that is encoded in the genome of human.


name: 1,5-Bis(4-methoxyphenyl)-3-(2,2,2-trifluoroethoxy)-1H-1,2,4 trazole, 5-methoxy C-11


An oxindole that is 5-amino-oxindole in which the 5-amino group has undergone formal condensation with the carboxy group of 3-(piperidin-1-yl)propanoic acid to give the corresponding carboxamide and in which the hydrogens at position 3 have been replaced by a (5-methoxy-1H-indol-3-yl)methylene group (Z configuration). It is an inhibitor of extracellular signal-regulated kinase (ERK) dimerisation.


PERF_MOUSE Perforin-1 (sprot)

A perforin-1 that is encoded in the genome of mouse.


name: RBP1_MOUSE RalA-binding protein 1 (sprot)

description: A RalA-binding protein 1 that is encoded in the genome of mouse.


name: NDH_MYCTU Type II NADH:quinone oxidoreductase Ndh (sprot)


name: NDHA_MYCTU Type II NADH:quinone oxidoreductase NdhA (sprot)


marinoquinoline B

A pyrroloquinoline that is 3H-pyrrolo[2,3-c]quinoline substituted by an isobutyl group at position 4. It is a natural product found in Ohtaekwangia kribbensis.


MARINOQUINOLINE A

A pyrroloquinoline that is 3H-pyrrolo[2,3-c]quinoline substituted by a methyl group at position 4. It is a natural product found in Ohtaekwangia kribbensis and Rapidithrix thailandica.


name: PSD11_HUMAN 26S proteasome non-ATPase regulatory subunit 11 (sprot)

description: A 26S proteasome non-ATPase regulatory subunit 11 that is encoded in the genome of human.


name: AAK1_MOUSE AP2-associated protein kinase 1 (sprot)

description: An AAK1 gene translation product (mouse), isoforms m1 and m2.


name: ANPRC_RAT Atrial natriuretic peptide receptor 3 (sprot)

description: An atrial natriuretic peptide receptor 3 that is encoded in the genome of rat.


name: 1,5-Methano-2H-2-benzazepine-2-carboxylic acid, 1,3,4,5-tetrahydro-8-(4-methyl-1-piperazinyl)-, phenylmethyl ester


name: HMDH_CRIGR 3-hydroxy-3-methylglutaryl-coenzyme A reductase (sprot)


oridonin

An organic heteropentacyclic compound and ent-kaurane diterpenoid with formula C20H28O6 isolated from the leaves of the medicinal herb Rabdosia rubescens.


A monocarboxylic acid that is phenylacetic acid in which the hydrogen at position 3 on the benzene ring is replaced by a hydroxy group.


name: MAGA4_HUMAN Melanoma-associated antigen 4 (sprot)

description: A melanoma-associated antigen 4 that is encoded in the genome of human.


name: SPNS2_MOUSE Sphingosine-1-phosphate transporter SPNS2 (sprot)

description: A sphingosine-1-phosphate transporter SPNS2 that is encoded in the genome of mouse.


name: 4-(1H-Indol-3-YL)-2,6-DI-ME-1,4-2H-pyridine-3,5-dicarboxylic acid dimethyl ester


name: ATG4A_HUMAN Cysteine protease ATG4A (sprot)

description: A cysteine protease ATG4A that is encoded in the genome of human.


daprodustat

A member of the class of  barbiturates that is barbituric acid substituted by cyclohexyl groups at positions 1 and 3, and by a (carboxymethyl)aminocarbonyl group at position 5. It is an inhibitor of hypoxia-inducible factor prolyl hydroxylase developed by GlaxoSmithKline for the treatment of anaemia in patients with chronic kidney disease.


name: Diethyl-carbamic acid 1H-indol-5-yl ester


name: N-{4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-phenyl} carbamic acid ethyl ester


NOX3_HUMAN NADPH oxidase 3 (sprot)

An NADPH oxidase 3 that is encoded in the genome of human.


name: PPAC_RAT Low molecular weight phosphotyrosine protein phosphatase (sprot)

description: A low molecular weight phosphotyrosine protein phosphatase that is encoded in the genome of rat.


name: CO2A1_HUMAN Collagen alpha-1(II) chain (sprot)

description: A collagen type II alpha chain that is encoded in the genome of human.


name: NR6A1_HUMAN Nuclear receptor subfamily 6 group A member 1 (sprot)

description: A nuclear receptor subfamily 6 group A member 1 that is encoded in the genome of human.


A member of the class of  morpholines that is  morpholine substituted by a 3-aminopropyl group a the N atom.


5-fluoroanthranilic acid

An aminobenzoic acid that is anthranilic acid in which the hydrogen at position 5 on the phenyl ring is replaced by fluorine.


name: ADCYA_RAT Adenylate cyclase type 10 (sprot)

description: An adenylate cyclase type 10 that is encoded in the genome of rat.


name: ALKB_ECOLI Alpha-ketoglutarate-dependent dioxygenase AlkB (sprot)

description: An alpha-ketoglutarate-dependent dioxygenase AlkB that is encoded in the genome of Escherichia coli K-12.


fluorescein

A xanthene dye that is highly fluorescent, detectable even when present in minute quantities. Used forensically to detect traces of blood, in analytical chemistry as an indicator in silver nitrate titrations and in microscopy.


RYR2_MOUSE Ryanodine receptor 2 (sprot)

A ryanodine receptor 2 that is encoded in the genome of mouse.


name: SENP3_HUMAN Sentrin-specific protease 3 (sprot)

description: A sentrin-specific protease 3 that is encoded in the genome of human.


COMPLESTATINS A

A heterodetic cyclic peptide that is chloropeptin II in which the indole moiety is oxidised to the corresponding 2-oxindole. It is a HIV-1 integrase inhibitor isolated from Streptomyces.


SAPPANCHALCONE

A member of the class of chalcones that consists of trans-chalcone substituted by hydroxy groups at positions 3, 4 and 4' and a methoxy group at position 2'. Isolated from Caesalpinia sappan, it exhibits neuroprotective and cytoprotective activity.


name: S12A2_HUMAN Solute carrier family 12 member 2 (sprot)

description: A solute carrier family 12 member 2 that is encoded in the genome of human.


AQP4_RAT Aquaporin-4 (sprot)

An aquaporin-4 that is encoded in the genome of rat.


2-aminopimelic acid

An amino dicarboxylic acid that is heptanedioic acid in which a hydrogen at position 2 is replaced by an amino group. It is a component of the cell wall peptidoglycan of bacteria.


name: Isoxazolyl-prodrug of distamycin (stallimycin)


name: IGS11_HUMAN Immunoglobulin superfamily member 11 (sprot)

description: An immunoglobulin superfamily member 11 that is encoded in the genome of human.


N-sulfo-D-glucosamine

The N-sulfoglucosamine formed by sulfating the amino group of D-glucosamine.


name: CLC4K_MOUSE C-type lectin domain family 4 member K (sprot)

description: A C-type lectin domain family 4 member K that is encoded in the genome of mouse.


An alpha-L-Fucp-(1->3)-[beta-D-Galp-(1->4)]-D-GlcpNAc where the glucosamine at the reducing end has beta-configuration at its anomeric centre. Commonly known as Lewis x trisaccharide or Le(x).


An N-substituted diamine that is ethylenediamine in which the four amino hydrogens are replaced by 2-pyridylmethyl groups.


name: UBP24_HUMAN Ubiquitin carboxyl-terminal hydrolase 24 (sprot)

description: A ubiquitin carboxyl-terminal hydrolase 24 that is encoded in the genome of human.


name: 3H-1-Benzazepine-4-carboxylic acid, 2-aMino-8-(3-cyanophenyl)-, ethyl ester


thiouracil

A nucleobase analogue that is uracil in which the oxo group at C-2 is replaced by a thioxo group.


name: MOT3_HUMAN Monocarboxylate transporter 3 (sprot)

description: A monocarboxylate transporter 3 that is encoded in the genome of human.


A ketone that is heptan-3-one substituted by a 4-hydroxy-3-methoxyphenyl group at position 1 and a phenyl group at position 7. Isolated from in Alpinia oxyphylla, it exhibits antineoplastic and inhibitory activities against COX-1, COX-2 and NO synthase.


An organic cation that is the conjugate acid of serpentine. It is the major species at pH 7.3.


name: PCSK9_MOUSE Proprotein convertase subtilisin/kexin type 9 (sprot)

description: A proprotein convertase subtilisin/kexin type 9 that is encoded in the genome of mouse.


His-Phe

A dipeptide obtained by formal condensation of the carboxy group of L-histidine with the amino group of L-phenylalanine.


name: CP4FB_HUMAN Cytochrome P450 4F11 (sprot)

description: A cytochrome P450 4F11 that is encoded in the genome of human.


PYRG1_HUMAN CTP synthase 1 (sprot)

A CTP synthase 1 that is encoded in the genome of human.


PYRG2_HUMAN CTP synthase 2 (sprot)

A CTP synthase 2 that is encoded in the genome of human.


PYRG2_RAT CTP synthase 2 (sprot)

A CTP synthase 2 that is encoded in the genome of rat.


PYRG2_MOUSE CTP synthase 2 (sprot)

A CTP synthase 2 that is encoded in the genome of mouse.


PYRG1_MOUSE CTP synthase 1 (sprot)

A CTP synthase 1 that is encoded in the genome of mouse.


name: 1-(3-(1H-pyrazolo[3,4-d]pyrimidin-4-ylamino) azepan-1-yl)-2-(3, 5-dichlorophenylamino) ethanone


AMPD2_MOUSE AMP deaminase 2 (sprot)

An AMP deaminase 2 that is encoded in the genome of mouse.


ESR1_BOVIN Estrogen receptor (sprot)

An estrogen receptor that is encoded in the genome of cow.


(+)-nyasol

A 1,3-bis(p-hydroxyphenyl)pentane-1,4-diene that has 1Z,3S configuration. A natural product found in Asparagus africanus and Asparagus cochinchinensis.


ST1A1_RAT Sulfotransferase 1A1 (sprot)

A protein that is a translation product of the Sult1a1 gene in rat.


name: FRS2_HUMAN Fibroblast growth factor receptor substrate 2 (sprot)

description: A fibroblast growth factor receptor substrate 2 that is encoded in the genome of human.


name: SHIP1_HUMAN Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 (sprot)

description: A phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1 that is encoded in the genome of human.


hydroxytyrosol

A member of the class of catechols that is benzene-1,2-diol substituted by a 2-hydroxyethyl group at position 4. Isolated from Olea europaea, it exhibits antioxidant and antineoplastic activities.


CRF_RAT Corticoliberin (sprot)

A corticoliberin that is encoded in the genome of rat.


CRF_HUMAN Corticoliberin (sprot)

A corticoliberin that is encoded in the genome of human.


name: MQMTN_HELPJ Aminodeoxyfutalosine nucleosidase (sprot)

description: A 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase that is encoded in the genome of Helicobacter pylori J99.


An organic bromide salt having 9-benzyl-2-butyl-1-(2-chlorophenyl)-9H-beta-carbolin-2-ium as the counterion


name: MOT4_MOUSE Monocarboxylate transporter 4 (sprot)

description: A monocarboxylate transporter 4 that is encoded in the genome of mouse.


3-O-methylgallic acid

A member of the class of benzoic acids that is gallic acid in which the phenolic hydroxy group at position 3 is converted into the corresponding methyl ether.


A secondary carboxamide resulting from the formal condensation of the carboxy group of 4-oxo-4H-pyrido[1,2-a]pyrimidine-2-carboxylic acid with the primary amino group of 1-[2-(aminomethyl)imidazo[1,2-a]pyridin-6-yl]-N-(cyclohexylmethyl)methanamine. It is a highly potent and selective first-in-class small molecule inhibitor of METTL3 (N6-adenosine-methyltransferase 70 kDa subunit) enzyme activity and exhibits anti-leukaemic activity.


pyripyropene A

A sesquiterpenoid that consists of (3S,4R,4aR,6S,6aS,12R,12aS,12bS)-4-(acetoxymethyl)-12-hydroxy-4,6a,12b-trimethyl-11-oxo-9-(pyridin-3-yl)-1,3,4,4a,5,6,6a,12,12a,12b-decahydro-2H,11H-benzo[f]pyrano[4,3-b]chromene-3,6-diol in which the hydrogens of the 3- and 6-hydroxy functions are substituted by acetyl groups.


OXLA_HUMAN L-amino-acid oxidase (sprot)

An L-amino-acid oxidase that is encoded in the genome of human.


ALBU_RABIT Albumin (sprot)

An albumin that is encoded in the genome of rabbit.


GETIACAULEIN

A member of the class of  xanthones that is 9H-xanthen-9-one substituted by hydroxy groups at positions 2 and 8 and methoxy groups at positions 1 and 6.


gentisin

A member of the class of  xanthones that is 9H-xanthen-9-one substituted by hydroxy groups at positions 1 and 7 and a methoxy group at position 3.


A member of the class of  xanthones that is  swertianin in which the hydroxy group at position 2 has been replaced by a methoxy group.


NORSWERTIANOLIN

A beta-D-glucoside that is bellidin in which a beta-D-glucopyranosyl residue is attached at position O-8. A natural product found particularly in Gentiana campestris and Gentiana germanica.


SWERTIANOLIN

A xanthone that is bellidifolin in which a beta-Dglucopyranosyl residue is attached at position O-8 via a glycosidic linkage. It is isolated particularly from Gentiana campestris and Gentiana germanica.


A member of the class of xanthones that is 9H-xanthene substituted by a methyl group at position 6, hydroxy groups at positions 3 and 8, an oxo group at position 9 and a methoxy carbonyl at position 1. It has been isolated from Microdiplodia species and Aspergillus sydowii.


A member of the class of 1,3-thiazoles that is 2-[2-(propan-2-ylidene)hydrazino]-1,3-thiazole carrying an additional 4-chlorophenyl substituent at position 4.


name: PTPRF_RAT Receptor-type tyrosine-protein phosphatase F (sprot)

description: A receptor-type tyrosine-protein phosphatase F that is encoded in the genome of rat.


PROCHLORAZ

A member of the class of ureas that is 1H-imidazole-1-carboxamide substituted by a propyl and a 2-(2,4,6-trichlorophenoxy)ethyl group at the amino nitrogen atom. A fungicide active against a wide range of diseases affecting field crops, fruit, turf and vegetables.


StemRegenin 1

Inhibitor of the aryl hydrocarbon receptor


name: 1H-Cyclopenta[7,8]naphtho[2,3-b]furan-7-carboxylic acid, 2,3,3a,10b-tetrahydro-10-hydroxy-3a,6-dimethyl-3-oxo-, methyl ester, trans-


name: TYTR_TRYCO Trypanothione reductase (sprot)


name: TRMD_ECOLI tRNA (guanine-N(1)-)-methyltransferase (sprot)

description: A tRNA (guanine-N(1)-)-methyltransferase TrmD that is encoded in the genome of Escherichia coli K-12.


name: {4-[5-(4-Fluoro-3-trifluoromethyl-phenylcarbamoyl)-naphthalen-2-yloxy]-pyrimidin-2-yl}carbamic acid methyl ester


A furofuran that consists of hydroxymethylphosphonic acid where the alcoholic OH group is carrying a ({4-[(2S,3R)-2-({[(3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yloxy]carbonyl}amino)-3-hydroxy-4-[(4-methoxyphenyl)sulfonyl](2-methylpropyl)amino}butyl]phenyl group.


name: WECA_MYCS2 Decaprenyl-phosphate N-acetylglucosaminephosphotransferase (sprot)


coumamycin

A hydroxycoumarin antibiotic that is obtained from Streptomyces rishiriensis and exhibits potent antibacterial and anticancer activity.


betamethasone phosphate

A steroid phosphate that is the 21-O-phospho derivative of betamethasone.


TSHR_RAT Thyrotropin receptor (sprot)

A thyrotropin receptor that is encoded in the genome of rat.


REBECCAMYCIN

An N-glycosyl compound consisting of a heteropolycyclic ring system with a glucosyl group attached to one of the indolic nitrogens.


SLN12_HUMAN Ribonuclease SLFN12 (sprot)

A ribonuclease SLFN12 that is encoded in the genome of human.


A pyrazolopyrimidine that is pyrazolo[1,5-a]pyrimidine which is substituted at positions 3, 5, and 7 by cyano, (4-methyl-3-propanamidophenyl)nitrilo and cyclopropylnitrilo groups, respectively. It is a potent and selective chemical probe for the pleiotropic kinase CK2.


name: GRM7_MOUSE Metabotropic glutamate receptor 7 (sprot)

description: A metabotropic glutamate receptor 7 that is encoded in the genome of mouse.


name: CTLA4_HUMAN Cytotoxic T-lymphocyte protein 4 (sprot)

description: A cytotoxic T-lymphocyte protein 4 that is encoded in the genome of human.


HEXD_HUMAN Hexosaminidase D (sprot)

A hexosaminidase D that is encoded in the genome of human.


An amino trisaccharide consisting of N-acetylglucosamine having a fucosyl residue attached at the 4-position via an alpha-linkage and a galactosyl residue attached at the 3-position via a beta-linkage.


An organic sodium salt that is the tetrasodium salt of 5'-phosphopyridoxal-6-azobenzene-2,4-disulfonic acid


SYP_ECOLI Proline--tRNA ligase (sprot)

A proline--tRNA ligase that is encoded in the genome of Escherichia coli K-12.


name: [(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl (2,5-diamino-5-oxopentyl) hydrogen phosphate


An alpha-1-antichymotrypsin that is encoded in the genome of human.


name: Benzenesulfonic acid, 2,2'-(1,2-ethenediyl)bis[5-azido-, disodium salt


name: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid, Sodium Salt


name: High Temperature Requirement A2 Inhibitor I


name: SMAD2_HUMAN Mothers against decapentaplegic homolog 2 (sprot)

description: A smad2 that is encoded in the genome of human.


name: NOXO1_HUMAN NADPH oxidase organizer 1 (sprot)

description: An NADPH oxidase organizer 1 that is encoded in the genome of human.


name: LPRM_ECOLX 23S rRNA methylase leader peptide (sprot)


name: ODPA_PIG Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial (Fragment) (sprot)


name: ACOX1_HUMAN Peroxisomal acyl-coenzyme A oxidase 1 (sprot)

description: A peroxisomal acyl-coenzyme A oxidase 1 that is encoded in the genome of human.


example 15 [WO2015079413]

A flavanone glycoside that is eriodictyol attached to a beta-D-glucopyranosyl residue at position 7 via a glycosidic linkage. It is an Nrf2 activator and provides protection against cisplatin-induced toxicity.


name: CISY2_MYCTU Putative citrate synthase 2 (sprot)


M2_I34A1 Matrix protein 2 (sprot)

An influenzavirus matrix protein 2 that is encoded in the genome of the H1N1 strain A/Puerto Rico/8/1934.


name: Z-3-(3,5-Dimethoxyphenyl)-2-{4-[4-(2,4-dioxothiazolidin-5-ylmethyl)-phenoxy]-phenyl}-acrylic acid methyl ester


An aromatic amide obtained by formal condensation of the carboxy group of 5-(5-chloro-2,4-dihydroxyphenyl)-4-(4-methoxyphenyl)pyrazole-3-carboxylic acid with the amino group of ethylamine.


name: BMI1_HUMAN Polycomb complex protein BMI-1 (sprot)

description: A Polycomb complex protein BMI-1 that is encoded in the genome of human.


name: CYSM_MYCTU O-phosphoserine sulfhydrylase (sprot)


name: CYSK2_MYCTU S-sulfocysteine synthase (sprot)


name: TRYS_CRIFA Trypanothione synthetase (sprot)


name: PDF2_ARATH Homeobox-leucine zipper protein PROTODERMAL FACTOR 2 (sprot)

description: A protein that is a translation product of the PDF2 gene in Arabidopsis thaliana.


ANGT_RAT Angiotensinogen (sprot)

An angiotensinogen that is encoded in the genome of rat.


ANGT_HUMAN Angiotensinogen (sprot)

An angiotensinogen that is encoded in the genome of human.


name: TGFB2_HUMAN Transforming growth factor beta-2 proprotein (sprot)

description: A TGF-beta 2 that is encoded in the genome of human.


saroglitazar

A monocarboxylic acid that is (2S)-2-ethoxy-3-(p-ethoxyphenyl)propanoic acid in which one of the methyl hydrogens of the p-ethoxy substituent has been replaced by the nitrogen of 2-methyl-5-[4-(methylthio)phenyl]-1H-pyrrole. An agonist at the subtypes alpha and gamma of the peroxisome proliferator-activated receptor (PPAR) with predominant PPARalpha activity, it is used in the treatment of type 2 diabetes.


name: LUXQ_VIBHA Autoinducer 2 sensor kinase/phosphatase LuxQ (sprot)


name: DNA-(apurinic or apyrimidinic site) endonuclease, initiator methionine removed form (human)

description: A DNA-(apurinic or apyrimidinic site) endonuclease (human) that has had the initiator methionine removed. UniProtKB:P27695, 2-318.


name: eukaryotic translation initiation factor 4E phosphorylated 1 (human)

description: A eukaryotic translation initiation factor 4E (human) that has been phosphorylated on the residue at the position equivalent to Ser-53 of the amino acid sequence represented by UniProtKB:P06730-1. Example: UniProtKB:P06730-1, Ser-53, MOD:00046.


name: serine/threonine-protein kinase VRK2 isoform h4 (human)

description: A serine/threonine-protein kinase VRK2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q86Y07-4.


14-3-3 protein gamma isoform 1 (human)

A 14-3-3 protein gamma isoform 1 that is encoded in the genome of human.


name: T-cell surface glycoprotein CD4 N-glycosylated 23 (human)

description: A T-cell surface glycoprotein CD4 (human) that has been N-glycosylated at the residue equivalent to Asn-296 of the amino acid sequence represented by UniProtKB:P01730-1, in which the glycan structure is represented by GlyTouCan:G65890UA. Example: UniProtKB:P01730-1, Asn-296, MOD:00160~GNO:G65890UA.


phenoxybenzoic acid

An aromatic ether that is diphenyl ether in which one of the hydrogens is replaced by a carboxy group.


(R)-3,5-bisphosphomevalonic acid

A carboxyalkyl phosphate that is mevalonic acid phosphorylated at positions 3 and 5.


name: membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase isoform h2 (human)

description: A membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q99640-2.


name: membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase isoform 3 (human)

description: A membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase isoform 3 that is encoded in the genome of human.


name: membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase isoform h1 (human)

description: A membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q99640-1.


name: membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase isoform h4 (human)

description: A membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q99640-4.


name: membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase phosphorylated form (human)

description: A membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (human) that includes at least one phosphorylated residue. UniProtKB:Q99640, MOD:00696.


name: prostate-specific antigen N-glycosylated 5 (human)

description: A prostate-specific antigen (human) that has been N-glycosylated at the residue equivalent to Asn-69 of the amino acid sequence represented by UniProtKB:P07288-1, in which the glycan composition is represented by GlyTouCan:G03574QJ. Example: UniProtKB:P07288-1, Asn-69, MOD:00160~GNO:G03574QJ.


name: dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

description: A protein that is a translation product of the human RPN1 gene or a 1:1 ortholog thereof.


An L-methionine derivative that is the ester obtained by formal condensation of the carboxy group of N-formyl-L-methionine with the 3'-hydroxy group of AMP.


A 1,2-diacyl-sn-glycerol 3-phosphate in which the acyl substituents at positions 1 and 2 are specified as oleoyl and icosanoyl (arachidoyl) respectively.


name: POU domain, class 3, transcription factor 2 isoform hN-OCT 5A (human)

description: A POU domain, class 3, transcription factor 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P20265-2.


name: POU domain, class 3, transcription factor 2

description: A protein that is a translation product of the human POU3F2 gene or a 1:1 ortholog thereof.


name: POU domain, class 3, transcription factor 2 isoform hN-OCT 3 (human)

description: A POU domain, class 3, transcription factor 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P20265-1.


name: POU domain, class 3, transcription factor 2 isoform hN-OCT 5B (human)

description: A POU domain, class 3, transcription factor 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P20265-3.


name: testis-specific serine/threonine-protein kinase 3 isoform 1 (human)

description: A testis-specific serine/threonine-protein kinase 3 isoform 1 that is encoded in the genome of human.


pneumococcal C-polysaccharide

A polysaccharide phosphate composed of a backbone of tetrasaccharide-ribitol repeating units that are linked to each other by a phosphodiester linkage between position 5 of a D-ribitol residue and position 6 of a beta-D-glucopyranosyl residue.


name: serine/threonine-protein phosphatase PP1-alpha catalytic subunit isoform 1 (human)

description: A serine/threonine-protein phosphatase PP1-alpha catalytic subunit isoform 1 that is encoded in the genome of human.


arginine derivative

An amino acid derivative resulting from reaction of arginine at the amino group, the carboxy group, or the guanidyl group, or from the replacement of any hydrogen of arginine by a heteroatom. The definition normally excludes peptides containing arginine residues.


L-arginine ester

Any ester of L-arginine or its derivatives.


L-arginine derivative

A proteinogenic amino acid derivative resulting from reaction of L-arginine at the amino group, the carboxy group, or the guanidyl group, or from the replacement of any hydrogen of L-arginine by a heteroatom.


An L-arginyl ester obtained by formal condensation of the carboxy group of L-arginine with the 3'-hydroxy group of AMP.


dimethylarginine

An arginine derivative that is arginine substituted by two methyl groups. A "closed" class.


N(omega)-phospho-L-arginine

An arginine derivative that is L-arginine substituted by a phosphono group at N(omega)-position.


L-arginyl-AMP

A purine ribonucleoside 5'-monophosphate that is adenosine 5'-monophosphate in which one of the hydroxy groups of the phosphate has been condensed with the carboxylic acid group of L-arginine.


name: signal transducer and activator of transcription 1-alpha/beta deaminated 3 (human)

description: A signal transducer and activator of transcription 1-alpha/beta (human) that has been deaminated on the residue at the position equivalent to Gln-285 of the amino acid sequence represented by UniProtKB:P42224-1. Example: UniProtKB:P42224-1, Gln-285, MOD:00685.


5-O-Phosphono-beta-D-ribofuranose in which the hydroxy group at position 1 is substituted by the 6-amino group of 2,5,6-triaminopyrimidin-4(3H)-one.


integrin beta-8 isoform h1 (human)

An integrin beta-8 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P26012-1.


isoheptadecanoyl-CoA

A methyl-branched fatty acyl-CoA obtained from the formal condensation of the thiol group of coenzyme A with the carboxy group of isoheptadecanoic acid.


(R)-norverapamil

2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl]amino}-2-(propan-2-yl)pentanenitrile that has R configuration.


(S)-norverapamil

2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl]amino}-2-(propan-2-yl)pentanenitrile that has S configuration.


A hydroxy fatty acyl-CoA that results from the formal condensation of the thiol group of coenzyme A with the carboxy group of 3-methylnonanoic acid.


name: tyrosine-protein kinase SYK isoform Long (human)

description: A tyrosine-protein kinase SYK isoform 1 that is encoded in the genome of human.


name: glutaminyl-peptide cyclotransferase isoform m1 (mouse)

description: A glutaminyl-peptide cyclotransferase (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9CYK2-1.


name: alpha-2A adrenergic receptor phosphorylated 1 (human)

description: An alpha-2A adrenergic receptor (human) that has been phosphorylated on the residue at the position equivalent to Tyr-156 of the amino acid sequence represented by UniProtKB:P08913. UniProtKB:P08913, Tyr-156, MOD:00048.


name: serine protease 1, signal peptide removed form (human)

description: A serine protease 1 (human) that has had the signal peptide removed. UniProtKB:P07477, 16-247.


name: calcium/calmodulin-dependent protein kinase type II subunit gamma isoform h2 (human)

description: A calcium/calmodulin-dependent protein kinase type II subunit gamma (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q13555-2.


16alpha-hydroxy steroid

A 16-hydroxy steroid in which the hydroxy group at position 16 has alpha-configuration.


name: catechol O-methyltransferase isoform Soluble (rat)

description: A catechol O-methyltransferase (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P22734-2.


organic anion

Any organic ion with a net negative charge.


coenzyme gamma-F420-2(5-)

The penta-anion obtained by removing protons from the imide nitrogen, phosphate, and carboxylic acid groups of coenzyme gamma-F420-2.


cytidine 5'-monophosphate(2-)

A pyrimidine nucleoside 5'-monophosphate(2-) that results from the removal of two protons from the phosphate group of cytidine 5'-monophosphate; major species at pH 7.3.


An isocitrate(3-) that is the conjugate base of L-threo-isocitric acid.


The tetra-anion obtained by removal of all of the protons from the phosphate groups of D-glycero-D-manno-heptose 1,7-bisphosphate.


The dianion resulting from the removal of two protons from the phosphate group of 2,5-diamino-6-(1-D-ribitylamino)pyrimidin-4(3H)-one 5'-phosphate.


The conjugate base of (S)-3-hydroxybutyric acid.


carboxylic acid trianion

A trianion containing at least one carboxy group.


Major species at pH 7.3.


An isocitrate(3-) that is the  conjugate base of L-erythro-isocitric acid.


nucleoside 5'-triphoshate(4-)

A ribonucleoside triphosphate oxoanion arising from global deprotonation of the  triphosphate groups of any nucleoside triphosphate; major species at pH 7.3.


An alpha-amino-acid anion that is the conjugate base of D-glutamic acid, having anionic carboxy groups and a cationic amino group


steroid glucosiduronic acid anion

A steroid conjugate anion formed by deprotonation of the carboxy group of any steroid glucosiduronic acid.


Trianion of xanthosine 5'-triphosphate arising from deprotonation of three of the four free triphosphate OH groups.


methyl-branched fatty acid anion

Any branched-chain fatty acid anion containing methyl branches only.


A carbohydrate acid derivative anion obtained by deprotonation of the carboxy group of any beta-D-glucuronoside.


A 3-hydroxy fatty acyl-CoA(4-) oxanion arising from deprotonation of the phosphate and diphosphate OH groups of 3-hydroxypentanoyl-CoA; major species at pH 7.3.


dicarboxylic acid dianion

A carboxylic acid dianion obtained by deprotonation of both carboxy groups of any dicarboxylic acid.


The dianion of the fragment of coenzyme F420 remaining after formal hydrolytic removal of all of the glutamate residues.


2-oxo monocarboxylic acid anion

An oxo monocarboxylic acid anion in which the oxo group is located at the 2-position.


L-alpha-amino acid anion

Conjugate base of an L-alpha-amino acid arising from deprotonation of the C-1 carboxy group.


An organophosphate oxoanion arising from deprotonation of the diphosphate OH groups of Mo(VI)-molybdopterin guanine dinucleotide.


dithiocarbamate anions

Any organic sulfur anion resulting from the removal of a proton from any N-substituted dithiocarbamic acid.


tricarboxylic acid anion

Any anion of a tricarboxylic acid  formed by deprotonation of at least one carboxy group.


coenzyme alpha-F420-3(5-)

The penta-anion obtained by removing protons from the phosphate and carboxylic acid groups of coenzyme alpha-F420-3.


organophosphate oxoanion

An organic phosphoric acid derivative in which one or more oxygen atoms of the phosphate group(s) has been deprotonated.


nucleoside 5'-monophosphate(2-)

The dianion of a nucleoside monophosphate: major species at pH 7.3.


hydroxy fatty acid anion

The conjugate base of any hydroxy fatty acid, formed by deprotonation of the carboxylic acid moiety.


name: omega-methyl-medium-chain fatty acid anion

description: A medium-chain fatty acid anion obtained by deprotonation of the carboxy group of any omega-methyl fatty acid; major species at pH 7.3.


long-chain fatty acid anion

A fatty acid anion with a chain length of C13 to C22.


Dianion of 1-deoxy-D-altro-heptulose 7-phosphate arising from deprotonation of the phosphate OH groups; major species at pH 7.3.


amidobenzoate

Any benzoate anion carrying one or more amido substituents.


An anionic phospholipid that is the conjugate base of 1-palmitoyl-2-azelaoyl-sn-glycero-3-phosphocholine, obtained by deprotonation of the free carboxy group; major species at pH 7.3.


The dianion obtained by removal of two protons from the phosphate group of D-glycero-alpha-D-manno-heptose 7-phosphate.


Fully deprotonated form of 5-diphospho-1D-myo-inositol 1,3,4,6-tetrakisphosphate; major species at pH 7.3


carboxylic acid dianion

Any dianion containing at least one carboxy group.


Trianion of F420-0 arising from deprotonation of the carboxylic acid and phosphate functions as well as the 3-position on the pyrimidinoquinoline ring system; major species at pH 7.3.


organosulfate oxoanion

An organic anion of general formula RS(=O)2O(-) where R is an organyl group.


2-hydroxy carboxylate

The conjugate base of a 2-hydroxy carboxylic acid.


octadecadienoate

A long-chain, unsaturated fatty acid anion formed by deprotonation of the carboxy group of any octadecadienoic acid; major species at pH 7.3.


polyunsaturated fatty acid anion

Any unsaturated fatty acid anion containing more than one C-C unsaturated bond.  Major species at pH 7.3.


medium-chain fatty acid anion

A fatty acid anion resulting from the deprotonation of the carboxylic acid moiety of a medium-chain fatty acid.


linolenate

A polyunsaturated fatty acid anion obtained by deprotonation of the carboxy group of either alpha- or gamma-linolenic acid.


An acyl-CoA(4-) obtained by deprotonation of the phosphate and diphosphate OH groups of 3,5,7-trioxododecanoyl-CoA; major species at pH 7.3.


fatty acid anion 12:0

Any saturated fatty acid anion containing 12 carbons. Formed by deprotonation of the carboxylic acid moiety. Major species at pH 7.3.


(R)-lactate

An optically active form of lactate having (R)-configuration.


alaninate

An alpha-amino-acid anion that is the conjugate base of alanine, arising from deprotonation of the carboxy group.


cyclic hexaadenylate(6-)

Cyclic hexaadenylate; major species at pH 7.3.


A dicarboxylate that contains four carbon atoms.


The dianion formed by removal of two protons from the phosphate group of 2,5-diamino-6-(1-D-ribosylamino)pyrimidin-4(3H)-one 5'-phosphate.


The tetra-anion obtained by removal of all of the protons from the phosphate groups of D-glycero-beta-D-manno-heptose 1,7-bisphosphate.


hydrogen ((13)C)carbonate

A carbon oxoanion that is hydrogencarbonate in which the carbon is present as its (13)C isotope.


Dianion of alpha-D-galactosyl undecaprenyl diphosphate arising from deprotonation of both free diphosphate OH groups.


oxo carboxylic acid anion

Any carboxylic acid anion containing at least one oxo group.


maleate

A dicarboxylic acid anion obtained by deprotonation of at least one of the carboxy groups of maleic acid.


oxopentanoates

The conjugate base of any oxopentanoic acid.


An organophosphate oxoanion arising from deprotonation of the four diphosphate OH groups of molybdate-bis(molybdopterin guanine dinucleotide); major species at pH 7.3.


organosulfonate oxoanion

An organic anion obtained by deprotonation of the sufonate group(s) of any organosulfonic acid.


N-acylglycinate

A carboxylic acid anion obtained by deprotonation of the carboxy group of any N-acylglycine.


unsaturated fatty acid anion

Any fatty acid anion containing at least one C-C unsaturated bond; formed by deprotonation of the carboxylic acid moiety.


pentacarboxylic acid anion

A carboxylic acid anion formed by deprotonation of at least one of the five carboxy groups of any pentacarboxylic acid.


glufosinate-P zwitterion(1-)

An organic anion resulting from the deprotonation of the phosphinic acid group of (2R)-glufosinate-P zwitterion.


iodothyroninate

An iodothyronine whose alpha carboxylic acid group of the tyrosine is ionized (not protonated).


poly(ribitol phosphate) polyanion

The polyanion of poly(ribitol phosphate) arising from global deprotonation of phosphate OH groups in the repeating units.


carbon oxoanion

A negative ion consisting solely of carbon and oxygen  atoms, and therefore having the general formula CxOy(n-) for some integers x, y and n.


(2R)-glufosinate zwitterion(1-)

An organic anion resulting from the deprotonation of the phosphinic acid group of (2R)-glufosinate zwitterion.


An anionic phospholipid obtained by deprotonation of the carboxy and phosphate groups of N-hexadecanoyl-O-(1-octadecanoyl-sn-glycero-3-phospho)-L-serine; major species at pH 7.3.


fatty acid anion

The conjugate base of a fatty acid, arising from deprotonation of the carboxylic acid group of the corresponding fatty acid.


hydroxy monocarboxylic acid anion

Any monocarboxylic acid anion carrying at least one hydroxy substituent.


Major microspecies at pH 7.3


3-methyl fatty acid anion

A methyl-branched fatty acid anion obtained by deprotonation of the carboxy group of any 3-methyl fatty acid; major species at pH 7.3.


An organophosphate oxoanion arising from deprotonation of the phospho and carboxy groups as well as protonation of the amino group of O(4)-phosphotyrosine


coenzyme alpha-F420-3(6-)

The hexaanion of coenzyme alpha-F420-3 arising from deprotonation of the carboxylic acid and phosphate functions as well as the 3-position on the pyrimidinoquinoline ring system; major species at pH 7.3.


name: straight-chain saturated fatty acid anion

description: Any saturated fatty acid anion lacking a carbon side-chain.


fatty acid anion 4:0

Any saturated fatty acid anion containing 4 carbons. Formed by deprotonation of the carboxylic acid moiety. Major species at pH 7.3.


An inositol phosphomannosylinositol phosphophytoceramide(2-) having an inositol 1-phosphoryl group linked at the 6-position to the mannose residue and a hexacosanoyl group amide-linked to a C18 sphinganine base, with no hydroxylation at C-4 of the long-chain base or on the C26 very-long-chain fatty acid. Major species at pH 7.3.


The dianion obtained by removal of two protons from the phosphate group of D-glycero-beta-D-manno-heptose 7-phosphate.


oxalate

A dicarboxylic acid anion obtained by deprotonation of at least one of the carboxy groups of oxalic acid.


octadecanoid anion

An unsaturated fatty acid anion obtained by the deprotonation of the carboxy group of any octadecanoid.


straight-chain fatty acid anion

A fatty acid anion formed by deprotonation of the carboxylic acid functional group of a straight-chain fatty acid.


An organophosphate oxoanion that is the dianionic form of O-phosphoserine having anionic phosphate and carboxy functions and a protonated amino group.


branched-chain amino-acid anion

A branched-chain amino acid whose alpha-carboxylic acid group is ionized.


steroid acid anion

Any anion formed by loss of a proton from a steroid acid.


chlorobenzoate

Any member of the class of benzoates in which the benzene ring is substituted by at least one chloro group.


omega-methyl fatty acid anion

A fatty acid anion obtained by deprotonation of the carboxy group of any omega-methyl fatty acid; major species at pH 7.3.


hippurates

An N-acylglycinate obtained by deprotonation of the carboxy group of hippuric acid (N-benzoylglycine) and its derivatives.


An organophosphate oxoanion arising from deprotonation of the four diphosphate OH groups of tungsten-bis(molybdopterin guanine dinucleotide); major species at pH 7.3.


benzoates

A monocarboxylic acid anion obtained by deprotonation of the carboxy group of any benzoic acid.


carbohydrate acid derivative anion

A carboxylic acid anion resulting from the deprotonation of the carboxy group of a carbohydrate acid derivative.


coenzyme F420-1(4-)

The tetraanion of coenzyme F420-1 arising from deprotonation of the carboxylic acid and phosphate functions as well as the 3-position on the pyrimidinoquinoline ring system; major species at pH 7.3.


hydroxybenzoate

Any benzoate derivative carrying a single carboxylate group and at least one hydroxy substituent.


name: branched-chain saturated fatty acid anion

description: Any saturated fatty acid anion with a carbon side-chain or isopropyl termination.


organic sulfur anion

An organic anion in which the charge resides on a sulfur atom.


alpha-amino-acid anion

An amino-acid anion obtained by deprotonation of any alpha-amino acid.


carbamate

Any ester of carbamic acid or its N-substituted derivatives.


monounsaturated fatty acid anion

Any unsaturated fatty acid anion with one double or triple bond in the fatty acid chain.


L-thyroxine sulfate(1-)

A thyroxine sulfate(1-) that has L-configuration. The major microspecies at pH 7.3.


fatty acid anion 8:0

Any saturated fatty acid anion containing 8 carbons. Formed by deprotonation of the carboxylic acid moiety. Major species at pH 7.3.


octadecenoate

A fatty acid anion containing 18 carbons and one double bond. Formed by deprotonation of the carboxylic acid group. Major species at pH 7.3.


The conjugate base of (R)-3-hydroxybutyric acid.


Trianion of xanthosine 5'-diphosphate arising from deprotonation of all three OH groups of the diphosphate.


name: Mo(VI)-oxido Se-molybdopterin cytosine dinucleotide(4-)

description: An organophosphate oxoanion obtained by deprotonation of the diphosphate OH groups of Mo(VI)-oxido Se-molybdopterin cytosine dinucleotide(2-).


The dianion obtained by removal of the two acidic protons from the phosphate group of 2-amino-5-formylamino-6-(1-D-ribosylamino)pyrimidin-4(3H)-one 5'-phosphate.


beta-D-glucosiduronate

A carbohydrate acid derivative anion obtained by deprotonation of the carboxy group of any beta-D-glucosiduronic acid; major species at pH 7.3.


The tetra-anion obtained by removal of all of the protons from the phosphate groups of D-glycero-alpha-D-manno-heptose 1,7-bisphosphate.


cholanic acid conjugate anion

An organic anion obtained by deprotonation of any cholanic acid conjugate.


inositol phosphate oxoanion

Any organophosphate oxoanion derived from an inositol phosphate.


short-chain fatty acid anion

Any fatty acid anion obtained by removal of a proton from the carboxy group of a short-chain fatty acid (chain length of less than C6).


A 3-hydroxy fatty acyl-CoA resulting from the formal condensation of the thiol group of coenzyme A with the carboxy group of (S)-3-hydroxypentanoic acid.


A linear 5'-hydroxy-diadenylate with a cyclic 2',3' phosphate terminus; major species at pH 7.3.


monocarboxylic acid anion

A carboxylic acid anion formed when the carboxy group of a monocarboxylic acid is deprotonated.


cholanic acid anion

Any steroid acid anion based on a cholanic acid skeleton.


carboxylic acid anion

The conjugate base formed when the carboxy group of a carboxylic acid is deprotonated.


A short-chain (3R)-hydroxy fatty acyl-CoA(4-) obtained by deprotonation of the phosphate and diphosphate OH groups of (3R)-hydroxypentanoyl-CoA; major species at pH 7.3.


thyroxine sulfate(1-)

Conjugate base of thyroxine sulfate having anionic carboxy and sulfate groups and the amino group protonated.


Trianion of GTP arising from deprotonation of three of the four phosphate OH groups.


saturated dicarboxylic acid dianion(2-)

A carboxylic acid dianion obtained by deprotonation of both carboxy groups of any dicarboxylic acid that contains no carbon-carbon double bonds.


phenylpyruvate

A 2-oxo monocarboxylic acid anion resulting from deprotonation of the carboxy group of either keto- or enol-phenylpyruvic acid.


UDP-L-iduronic acid

A UDP-sugar in which the sugar component is L-iduronic acid.


thiamine(1+) triphosphate(4-)

Trianion of thiamine(1+) diphosphate arising from deprotonation of the four OH groups of the triphosphate.


An organophosphate oxoanion obtained by deprotonation of the phosphate OH group of 2-aminobenzoyl-AMP; major microspecies at pH 7.3.


monohydroxybenzoate

A hydroxybenzoate carrying a single hydroxy substituent at unspecified position.


saturated fatty acid anion

Any fatty acid anion in which there is no C-C unsaturation.


coenzyme gamma-F420-2(4-)

The tetra-anion obtained by removing protons from the phosphate and carboxylic acid groups of coenzyme gamma-F420-2.


An alpha-amino-acid anion that is the conjugate base of L-glutamic acid, having anionic carboxy groups and a cationic amino group


A isocitrate(3-) that is the conjugate base of D-erythro-isocitric acid.


malate

A dicarboxylic acid anion obtained by deprotonation of at least one of the carboxy groups of malic acid.


A monohydroxybenzoate that is obtained by removal of a proton from the carboxylic acid group of 5-nitrosalicylic acid.


Major species at pH 7.3.


An L-alpha-amino acid anion that is the dianion obtained by the deprotonation of the both the carboxy groups of L-glutamic acid.


The dianion obtained by removal of two protons from the phosphate group of D-glycero-D-manno-heptose 7-phosphate.


oxo fatty acid anion

A fatty acid anion carrying one or more oxo substituents


texas red DHPE(1-)

An anionic fluorescent dye consisting of an organic heteroheptacyclic moiety conjugated to a phosphatidylethanolamine group via a sulphonamide bond.


penicillinate anion

Any anion formed by loss of a proton from the carboxy group of a penicillin.


thiamine(1+) diphosphate(3-)

Dianion of thiamine(1+) diphosphate arising from deprotonation of the three OH groups of the diphosphate.


ribonucleoside triphosphate oxoanion

An organophosphate anion resulting from deprotonation of at least one of the acidic hydroxy groups from the triphosphate moiety of a nucleoside triphosphate.


quinolinemonocarboxylate

A monocarboxylic acid anion that is the monoanion obtained by the deprotonation of the carboxy group attached to the quinoline skeleton


fatty acid anion 3:0

Any saturated fatty acid anion containing 3 carbons. Formed by deprotonation of the carboxylic acid moiety. Major species at pH 7.3.


Major microspecies at pH 7.3


An octadecenoate in which the double bond is at C-9.


thiamine(1+) monophosphate(2-)

An organophosphate oxoanion that is the conjugate base of thiamine(1+) monophosphate(1-), arising from the deprotonation of the phosphate group. Major microspecies at pH 7.3.


A mannosyl-alpha-1->6-inositol phosphorylceramide(1minus) having an acyl group attached to the ceramide nitrogen and a d20:0 sphingoid base; major species at pH 7.3.


suberate

A dicarboxylic acid anion obtained by deprotonation of at least one of the carboxy groups of suberic acid.


cyclic tetraadenylate(4-)

Cyclic tetraadenylate; major species at pH 7.3.