name: GTR9_HUMAN Solute carrier family 2, facilitated glucose transporter member 9 (sprot)

description: A solute carrier family 2, facilitated glucose transporter member 9 that is encoded in the genome of human.


name: L_HRSVA RNA-directed RNA polymerase L (sprot)


canagliflozin

A C-glycosyl compound that is used (in its hemihydrate form) for treatment of type II diabetes via inhibition of sodium-glucose transport protein subtype 2.


name: DBF4A_HUMAN Protein DBF4 homolog A (sprot)

description: A protein DBF4 homolog A that is encoded in the genome of human.


name: NOS3_RAT Nitric oxide synthase 3 (sprot)

description: A nitric oxide synthase 3 that is encoded in the genome of rat.


name: KCNK9_HUMAN Potassium channel subfamily K member 9 (sprot)

description: A potassium channel subfamily K member 9 that is encoded in the genome of human.


name: CXCR4_BOVIN C-X-C chemokine receptor type 4 (sprot)


name: Preparation of 17-methylmorphinan-3-yl (2-methoxyethyl)carbamate


name: Preparation of tert-butyl (17-methylmorphinan-3-yl)carbamate


name: [3-(4-Bromo-2-methyl-2h-pyrazol-3-yl)-4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-carbamic acid isobutyl ester


MT2_HUMAN Metallothionein-2 (sprot)

A metallothionein-2 that is encoded in the genome of human.


name: PASK_HUMAN PAS domain-containing serine/threonine-protein kinase (sprot)

description: A PAS domain-containing serine/threonine-protein kinase that is encoded in the genome of human.


A member of the class of indoles that is 1H-indole substituted by a 5-chloro-2-[3-(4-{[(2E)-4-(dimethylamino)but-2-enoyl]amino}benzamido)anilino]pyrimidin-4-yl group at position 3. It is a selective and potent covalent inhibitor of CDK7 that exhibits anti-proliferative effects in cancer cell lines.


PNOC_HUMAN Prepronociceptin (sprot)

A nociceptin that is encoded in the genome of human.


name: DHE4_HUMAN Glutamate dehydrogenase 2, mitochondrial (sprot)

description: A glutamate dehydrogenase 2, mitochondrial that is encoded in the genome of human.


name: Preparation of 1-(1-allylcyclopropylsulfonyl)-6-bromo-N-((4, 6-dimethyl-2-oxo-1, 2-dihydropyridin-3-yl)methyl)-1H-indole-4-carboxamide


name: (S)-4-((2-(dimethylamino)-2-oxoethyl) (4-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl) butyl)amino)-2-((2-(trifluoromethyl)pyrimidin-4-yl) amino) butanoic Acid


name: 3-{[4-(Methylsulfanyl)phenyl] carbamoyl} spiro[bicyclo[2.2.1]heptane-7,1''-cyclopropane]-5-ene-2-carboxylic acid


name: RPOA_ECOLI DNA-directed RNA polymerase subunit alpha (sprot)

description: A DNA-directed RNA polymerase subunit alpha that is encoded in the genome of Escherichia coli K-12.


name: RPOA_MYCTU DNA-directed RNA polymerase subunit alpha (sprot)


name: RPOA_STAAN DNA-directed RNA polymerase subunit alpha (sprot)


name: TRPC6_HUMAN Short transient receptor potential channel 6 (sprot)

description: A short transient receptor potential channel 6 that is encoded in the genome of human.


name: DPP4_MOUSE Dipeptidyl peptidase 4 (sprot)

description: A dipeptidyl peptidase 4 that is encoded in the genome of mouse.


name: LYOX_PIG Protein-lysine 6-oxidase (sprot)


name: LYOX_MOUSE Protein-lysine 6-oxidase (sprot)

description: A protein-lysine 6-oxidase that is encoded in the genome of mouse.


name: US10828290, Example 46 (Diastereoisomer 1)


name: US10828290, Example 46 (Diastereoisomer 2)


name: NEP1_HUMAN Ribosomal RNA small subunit methyltransferase NEP1 (sprot)

description: A ribosomal RNA small subunit methyltransferase NEP1 that is encoded in the genome of human.


name: (2R,4R)-4-[(5-Acetyl-1H-pyrazole-3-carbonyl)amino]-5-(3'-chlorobiphenyl-4-yl)-2-hydroxypentanoic Acid Ethyl Ester


name: KAT6A_HUMAN Histone acetyltransferase KAT6A (sprot)

description: A histone acetyltransferase KAT6A that is encoded in the genome of human.


name: SOS1_HUMAN Son of sevenless homolog 1 (sprot)

description: A son of sevenless homolog 1 that is encoded in the genome of human.


name: tert-Butyl 4-((4-((2-(5-bromothien-2-yl)) cyclopropyl)amino)methyl)-4-fluoropiperidin-1-yl)methyl) benzoate


name: tert-Butyl 4-((4-(((2-(5-(4-chlorophenyl) thiophen-2-yl)cyclopropyl)amino) methyl)-4-fluoropiperidin-1-yl) methyl)benzoate


name: tert-Butyl 4-((4-fluoro-4-(((2-(5-phenyl-thiophen-2-yl)cyclopropyl) amino)methyl)piperidin-1-yl) methyl)benzoic acid


name: Piperidin-4-ylmethyl 4-fluoro-4-(((2-(6-(4-fluorophenyl) pyridin-3-yl)cyclopropyl)amino) methyl)piperidine-1-carboxylate


A member of the class of piperidines that is piperidine substituted by (4-carboxyphenyl)methyl and {[(1R,2S)-2-phenylcyclopropyl]amino}methyl groups at positions 1 and 4, respectively. It is a potent and irreversible inhibitor of lysine specific demethylase 1 (LSD1, also known as KDM1A). It was under clinical investigation for the treatment of acute myeloid leukaemia and small cell lung carcinoma.


name: MP2K5_HUMAN Dual specificity mitogen-activated protein kinase kinase 5 (sprot)

description: A dual specificity mitogen-activated protein kinase kinase 5 that is encoded in the genome of human.


name: MP2K7_HUMAN Dual specificity mitogen-activated protein kinase kinase 7 (sprot)

description: A dual specificity mitogen-activated protein kinase kinase 7 that is encoded in the genome of human.


name: 1-((4-(4-Chloro-3,5-dimethylphenoxy) phenyl) sulfonyl)-1,2,3,4-tetrahydroquinoline-6-carboxylic acid


name: 1-(3-Chloro-4-cyano-phenyl)-7-oxo-4,5,6,7-tetrahydro-1H-benzoimidazole-5-carboxylic acid ethyl ester


name: 4-(5,5-Dimethyl-7-oxo-4,5,6,7-tetrahydro-benzoimidazol-1-yl)-benzoic acid methyl ester


name: 4-(5,5-Dimethyl-7-oxo-4,5,6,7-tetrahydro-benzoimidazol-1-ylmethyl)-benzoic acid methyl ester


name: AA2AR_MOUSE Adenosine receptor A2a (sprot)

description: An adenosine receptor A2a that is encoded in the genome of mouse.


name: 8-(3-Methyiimidazo[l,2-a]pyridin-6-yl)-7-(oxazo l-2-yl)-2-((tetrahydrofuran-2-yl)methyl)-[l,2,4] triazolo[l,5-c]pyrimidin-5-amine (isomer 1)


name: 8-(3-Methylimidazo[l,2-a]pyridin-6-yl)-7-(oxazo l-2-yl)-2-((tetrahydrofuran-2-yl)methyl)-[l,2,4] triazolo[l,5-c]pyrimidin-5-amine (isomer 2)


name: 8-(3-Methylimidazo[l,2-a]pyridin-6-yl)-7-(oxazo l-2-yl)-2-((tetrahydrofuran-3-yl)methyl)-[l,2,4] triazolo[l,5-c]pyrimidin-5-amine (isomer 1)


name: 8-(3-Methylimidazo[l,2-a]pyridin-6-yl)-7-(oxazo l-2-yl)-2-((tetrahydrofiiran-3-yl)methyl)-[l,2,4] triazolo[l,5-c]pyrimidin-5-amine (isomer 2)


name: 2-(2,6-Difluorobenzyl)-8-(3-methylimidazo[l,2-a] pyridin-6-yl)-7-morpholino-[1,2,4] triazolo[1,5-c] pyrimidin-5-amine


name: PA_I75A3 Polymerase acidic protein (sprot)


NRAM_I33A0 Neuraminidase (sprot)

A neuraminidase subtype N1 (Influenza A virus) that is encoded in the genome of the H1N1 strain A/Wilson-Smith/1933.


NRAM_I71A1 Neuraminidase (sprot)

A neuraminidase subtype N2 (Influenza A virus) that is encoded in the genome of the H3N2 strain A/Memphis/1/1971.


name: ARF6_HUMAN ADP-ribosylation factor 6 (sprot)

description: An ADP-ribosylation factor 6 that is encoded in the genome of human.


DAB2_HUMAN Disabled homolog 2 (sprot)

A disabled homolog 2 that is encoded in the genome of human.


name: ATG7_HUMAN Ubiquitin-like modifier-activating enzyme ATG7 (sprot)

description: A ubiquitin-like modifier-activating enzyme ATG7 that is encoded in the genome of human.


name: POLS_CHIKS Structural polyprotein (sprot)


name: R1AB_CVHOC Replicase polyprotein 1ab (sprot)


name: LPXC_KLEP7 UDP-3-O-acyl-N-acetylglucosamine deacetylase (sprot)


An L-threonine derivative obtained by formal condensation of the carboxy group of 4-({4-[(morpholin-4-yl)methyl]phenyl}ethynyl)benzoic acid with the amino group of N-hydroxy-L-threoninamide.


name: T22D3_HUMAN TSC22 domain family protein 3 (sprot)

description: A TSC22 domain family protein 3 that is encoded in the genome of human.


budesonide

A glucocorticoid steroid having a highly oxygenated pregna-1,4-diene structure. It is used mainly in the treatment of asthma and non-infectious rhinitis and for treatment and prevention of nasal polyposis.


name: HIPK4_HUMAN Homeodomain-interacting protein kinase 4 (sprot)

description: A homeodomain-interacting protein kinase 4 that is encoded in the genome of human.


name: peptidomimetic coronavirus 3CLpro inhibitors 17


telaprevir

An oligopeptide consisting of N-(pyrazin-2-ylcarbonyl)cyclohexylalanyl, 3-methylvalyl, octahydrocyclopenta[c]pyrrole-1-carboxy, and 3-amino-N-cyclopropyl-2-oxohexanamide residues joined in sequence. Used for treatment of chronic hepatitis C virus genotype 1 infection.


name: UBP28_HUMAN Ubiquitin carboxyl-terminal hydrolase 28 (sprot)

description: A ubiquitin carboxyl-terminal hydrolase 28 that is encoded in the genome of human.


name: UBP25_HUMAN Ubiquitin carboxyl-terminal hydrolase 25 (sprot)

description: A ubiquitin carboxyl-terminal hydrolase 25 that is encoded in the genome of human.


name: US10889595, Control Example (Control sample B-Secretase inhibitor IV)


name: CDK12_HUMAN Cyclin-dependent kinase 12 (sprot)

description: A cyclin-dependent kinase 12 that is encoded in the genome of human.


name: CDK13_HUMAN Cyclin-dependent kinase 13 (sprot)

description: A cyclin-dependent kinase 13 that is encoded in the genome of human.


name: MPRI_HUMAN Cation-independent mannose-6-phosphate receptor (sprot)

description: A cation-independent mannose-6-phosphate receptor that is encoded in the genome of human.


name: PDE6A_HUMAN Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha (sprot)

description: A rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha that is encoded in the genome of human.


name: PDE6D_HUMAN Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (sprot)

description: A retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta that is encoded in the genome of human.


name: Benzene-1,4-disulfonic acid 1-diethylamide 4-(furan-2-ylmethyl-pyridin-2-ylmethyl-amide)


name: Benzene-1,4-disulfonic acid 1-(cyclohexyl-methyl-amide) 4-[cyclohexyl-(3,4,5-trimethoxy-benzyl)-amide]


name: Benzene-1,4-disulfonic acid 1-[cyclohexyl-(4-fluoro-benzyl)-amide] 4-[(tetrahydro-furan-2-ylmethyl)-amide]


name: Benzene-1,4-disulfonic acid 1-(benzyl-methyl-amide) 4-[cyclopentyl-(4-fluoro-benzyl)-amide]


name: Synthesis of (3-methoxy-4-((4-methoxy-7H-pyrrolo[2,3-d]pyrimidin-2-yl)amino)phenyl) (morpholino)methanone


A quinolinemonocarboxylate that is the conjugate base of brequinar arising from the deprotonation of the carboxy group. Major microspecies at pH 7.3.


name: SCD5_HUMAN Stearoyl-CoA desaturase 5 (sprot)

description: A stearoyl-CoA desaturase 5 that is encoded in the genome of human.


name: FA2H_HUMAN Fatty acid 2-hydroxylase (sprot)

description: A fatty acid 2-hydroxylase that is encoded in the genome of human.


name: R1AB_CVHNL Replicase polyprotein 1ab (sprot)


name: R1AB_CVHN5 Replicase polyprotein 1ab (sprot)


name: (S)-2-(2-(1-(4-((2,3-difluorophenoxy) methyl)phenyl)imidazo [1,5-a]pyrazin-3-yl) pyrrolidin-1-yl)prop-2-en-l-one


name: (S)-1-(2-(1-(4-((2,3-difluorophenoxy) methyl)phenyl)imidazo [1,5-a]pyrazin-3-yl) pyrrolidin-1-yl)but-2-yn-1-one


name: (S)-1-(2-(1-(4-((3,4-difluorophenoxy) methyl)phenyl)imidazo [1,5-a]pyrazin-3-yl) pyrrolidin-1-yl)prop-2-en-1-one


name: (S)-l-(2-(1-(4-((3,4-difluorophenoxy) methyl)phenyl)imidazo [1,5-a]pyrazin-3-yl) pyrrolidin-1-yl)but-2-yn-1-one


name: (S)-1-(2-(1-(4-((3-fluorophenoxy) methyl)phenyl)imidazo [1,5-a]pyrazin-3-yl) pyrrolidin-1-yl)prop-2-en-1-one


name: (S)-1-(2-(1-(4-((2-fluorophenoxy) methyl)phenyl)imidazo [1,5-a]pyrazin-3-yl) pyrrolidin-1-yl)but-2-yn-1-one


name: (S)-1-(2-(1-(4-((3-fluorophenoxy) methyl)phenyl)imidazo [1,5-a]pyrazin-3-yl) pyrrolidin-1-yl)but-2-yn-1-one


name: (S)-1-(2-(1-(4-((3,4-difluorophenoxy) methyl)phenyl)imidazo [1,5-a]pyrazin-3-yl) piperidin-1-yl)prop-2-en-1-one


name: (S)-1-(2-(1-(4-((3,4-difluorophenoxy) methyl)phenyl)imidazo [1,5-a]pyrazin-3-yl) piperidin-1-yl)but-2-yn-1-one


name: (S)-1-(2-(1-(4-((3-fluorophenoxy)methyl) phenyl)-8-methylimidazo [1,5-a]pyrazin-3-yl) piperidin-1-yl)but-2-yn-1-one


name: (S)-1-(2-(1-(4-((2,3-difluorophenoxy) methyl)phenyl)imidazo [1,5-a]pyrazin-3-yl) piperidin-1-yl)prop-2-en-1-one


name: (S)-1-(2-(1-(4-((2,3-difluorophenoxy) methyl)phenyl)imidazo [1,5-a]pyrazin-3-yl) piperidin-1-yl)but-2-yn-1-one


name: (S)-1-(2-(1-(4-((2-fluoro-3-methoxyphenoxy) methyl)phenyl)imidazo [1,5-a]pyrazin-3-yl) pyrrolidin-1-yl)but-2-yn-1-one


name: (S)-1-(2-(1-(4-((2-fluoro-3-methoxyphenoxy) methyl)phenyl)imidazo [1,5-a]pyrazin-3-yl) pyrrolidin-1-yl)prop-2-en-1-one


name: (R)-4-(3-(1-(but-2-ynoyl) pyrrolidin-3-yl)imidazo[1,5-a] pyrazin-1-yl)-N-(4-(trifluoromethyl) pyridin-2-yl)benzamide


name: SH2B2_HUMAN SH2B adapter protein 2 (sprot)

description: An SH2B adapter protein 2 that is encoded in the genome of human.


RASK_HUMAN GTPase KRas (sprot)

A GTPase KRas that is encoded in the genome of human.


name: I23O1_MOUSE Indoleamine 2,3-dioxygenase 1 (sprot)

description: An indoleamine 2,3-dioxygenase 1 that is encoded in the genome of mouse.


enasidenib

A 1,3,5-triazine which is substituted by (2-hydroxy-2-methylpropyl)nitrilo, 6-(trifluoromethyl)pyridin-2-yl and [2-(trifluoromethyl)pyridin-4-yl]nitrilo groups at positions 2,4 and 6, respectively. It is an isocitrate dehydrogenase-2 (IDH2) inhibitor which has been approved for the treatment of adults with relapsed or refractory acute myeloid leukaemia (AML).


RETN_HUMAN Resistin (sprot)

A resistin that is encoded in the genome of human.


name: 2-(5-(cyclopropylmethyl)-3-(4-fluoro-3-(6-isopropyl-2,6-diazaspiro[3.3] heptan-2-yl)phenyl)-4-(3-fluoro-4-sulfamoylbenzyl)-1H-pyrazol-1-yl)thiazole-4-carboxylic acid; 1H-NMR (MeOD) 948; acid


name: 2-(5-amino-3-(3,4-difluorophenyl)-4-(4-sulfamoylbenzyl)-1H-pyrazol-1-yl)thiazole-4-carboxylic acid MS (M + H)+ = 492


name: ethyl 2-(3-([1,1''-biphenyl]-3-yl)-5-amino-4-(4-sulfamoylbenzyl)-1H-pyrazol-1-yl)thiazole-4-carboxylate (M + H)+ = 560


name: ethyl 2-(5-amino-3-phenyl-4-(4-sulfamoylbenzyl)-1H-pyrazol-1-yl)thiazole-4-carboxylate (M + H)+ = 484


name: 2-(3-(3,4-difluorophenyl)-5-methoxy-4-(4-sulfamoylbenzyl)-1H-pyrazol-1-yl)thiazole-4-carboxylic acid (M + H)+ = 507


name: 2-(3-phenyl-4-(4-sulfamoylphenyl)-1H-pyrazol-1-yl)thiazole-4-carboxylic acid (M + H)+ = 427


name: ethyl 2-(3-phenyl-4-(4-sulfamoylbenzyl)-5-(trifluoromethyl)-1H-pyrazol-1-yl)thiazole-4-carboxylate (M + H)+ = 537


name: 2-(3-phenyl-5-(pyridin-3-ylamino)-4-(4-sulfamoylbenzyl)-1H-pyrazol-1-yl)thiazole-4-carboxylic acid (M + H)+ = 533


name: 2-(5-((1H-tetrazol-5-yl)methyl)-3-phenyl-4-(4-sulfamoylbenzyl)-1H-pyrazol-1-yl)thiazole-4-carboxylic acid (M + H)+ = 523


name: ethyl 2-(5-amino-3-(3,4-difluorophenyl)-4-(4-sulfamoylbenzyl)-1H-pyrazol-1-yl)thiazole-4-carboxylate (M + H)+ = 520


name: 2-(5-amino-3-phenyl-4-(4-sulfamoylbenzyl)-1H-pyrazol-1-yl)-5-methylthiazole-4-carboxylic acid (M + H)+ = 470


name: 2-(5-amino-3-phenyl-4-(4-sulfamoylbenzyl)-1H-pyrazol-1-yl)thiazole-4-carboxylic acid (M + H)+ = 456


name: ethyl 2-(5-amino-3-phenyl-4-(4-sulfamoylbenzyl)-1H-pyrazol-1-yl)oxazole-4-carboxylate (M + H)+ = 468


name: 2-(5-amino-3-phenyl-4-(4-sulfamoylbenzyl)-1H-pyrazol-1-yl)oxazole-4-carboxylic acid (M + H)+ = 440


name: 2-(3-isopropyl-5-phenyl-4-(4-sulfamoylbenzyl)-1H-pyrazol-1-yl)thiazole-4-carboxylic acid (M + H)+ = 483


name: ethyl 2-(3-([1,1''-biphenyl]-3-yl)-4-((4-sulfamoylphenyl)amino)-1H-pyrazol-1-yl)thiazole-4-carboxylate (M + H)+ = 546


name: ethyl 2-(5-cyclopropyl-3-phenyl-4-(4-sulfamoylphenoxy)-1H-pyrazol-1-yl)thiazole-4-carboxylate (M + H)+ = 511


name: cyclopropyl-5-phenyl-4-(4-sulfamoylphenoxy)-1H-pyrazol-1-yl)thiazole-4-carboxylic acid (M + H)+ = 483


name: 2-(3-cyclopentyl-5-phenyl-4-(4-sulfamoylphenoxy)-1H-pyrazol-1-yl)thiazole-4-carboxylic acid (M + H)+ = 511


name: 2-(5-cyclopentyl-3-phenyl-4-(4-sulfamoylphenoxy)-1H-pyrazol-1-yl)thiazole-4-carboxylic acid (M + H)+ = 511


name: 2-(3-cyclohexyl-5-phenyl-4-(4-sulfamoylphenoxy)-1H-pyrazol-1-yl)thiazole-4-carboxylic acid (M + H)+ = 525


name: 2-(5-cyclohexyl-3-phenyl-4-(4-sulfamoylphenoxy)-1H-pyrazol-1-yl)thiazole-4-carboxylic acid (M + H)+ = 525


name: 2-(3-cyclopentyl-5-phenyl-4-(4-sulfamoylphenoxy)-1H-pyrazol-1-yl)thiazole-4-carboxylic acid (M + H)+ = 508


name: 2-(5-cyclopentyl-3-phenyl-4-(4-sulfamoylbenzyl)-1H-pyrazol-1-yl)thiazole-4-carboxylic acid (M + H)+ = 508


name: 2-(3-cyclohexyl-5-phenyl-4-(4-sulfamoylbenzyl)-1H-pyrazol-1-yl)thiazole-4-carboxylic acid (M + H)+ = 523


name: 2-(5-cyclohexyl-3-phenyl-4-(4-sulfamoylbenzyl)-1H-pyrazol-1-yl)thiazole-4-carboxylic acid (M + H)+ = 523


name: 2-(5-(oxiran-2-yl)-3-phenyl-4-(4-sulfamoylbenzyl)-1H-pyrazol-1-yl)thiazole-4-carboxylic acid (M + H)+ = 483


name: 2-(3-phenyl-5-(phenylethynyl)-4-(4-sulfamoylbenzyl)-1H-pyrazol-1-yl)thiazole-4-carboxylic acid (M + H)+ = 541


name: cyclopropyl-4-(2-fluoro-4-sulfamoylbenzyl)-1H-pyrazol-1-yl)thiazole-4-carboxylic acid (M + H)+ = 575


name: 2-(5-([1,1''-biphenyl]-3-yl)-3-cyclopropyl-4-(4-sulfamoylbenzyl)-1H-pyrazol-1-yl)thiazole-4-carboxylic acid (M + H)+ = 557


name: 2-(5-([1,1''-biphenyl]-3-yl)-3-cyclopropyl-4-(4-sulfamoylphenoxy)-1H-pyrazol-1-yl)thiazole-4-carboxylic acid (M + H)+ = 559


name: 2-(3-(cyclopropylmethyl)-5-phenyl-4-(4-sulfamoylbenzyl)-1H-pyrazol-1-yl)thiazole-4-carboxylic acid (M + H)+ = 495


name: 2-(3-([1,1''''-biphenyl]-3-yl)-5-(2-cyclopropylethyl)-4-(4-sulfamoylbenzyl)-1H-pyrazol-1-yl)thiazole-4-carboxylic acid (M + H)+ = 585


name: 2-(5-([1,1''-biphenyl]-3-yl)-3-(2-cyclopropylethyl)-4-(4-sulfamoylbenzyl)-1H-pyrazol-1-yl)thiazole-4-carboxylic acid (M + H)+ = 585


name: 2-(5-([1,1''-biphenyl]-3-yl)-3-(2,2-difluorocyclopropyl)-4-(4-sulfamoylbenzyl)-1H-pyrazol-1-yl)thiazole-4-carboxylic acid (M + H)+ = 593


name: 2-(5-([1,1''-biphenyl]-3-yl)-5-((2,2-difluorocyclopropyl) methyl)-4-(4-sulfamoylbenzyl)-1H-pyrazol-1-yl)thiazole-4-carboxylic acid (M + H)+ = 607


name: 2-(3-(6-fluoro-3''-methoxy-[1,1''-biphenyl]-3-yl)-4-(4-sulfamoylbenzyl)-1H-pyrazol-1-yl)thiazole-4-carboxylic acid; MS (ES) 565.0 (M + H)+ LCMS RT = 1.08 min.


name: 2-(3-(3''-chloro-6-fluoro-[1,1''-biphenyl]-3-yl)-4-(4-sulfamoylbenzyl)-1H-pyrazol-1-yl)thiazole-4-carboxylic acid; MS (ES) 568.9 (M + H)+ LCMS RT = 1.16 min.


name: 2-(3-(3'',6-difluoro-[1,1''-biphenyl]-3-yl)-4-(4-sulfamoylbenzyl)-1H-pyrazol-1-yl)thiazole-4-carboxylic acid; MS (ES) 552.9 (M + H)+ LCMS RT = 1.12 min.


name: 2-(4-(4-sulfamoylbenzyl)-3-(3-((tetrahydrofuran-3-yl)methoxy)phenyl)-1H-pyrazol-1-yl)thiazole-4-carboxylic acid; MS (ES) 540.7 (M + H)+ LCMS RT = 1.13 min.


name: 2-(3-(3-((3-methoxybenzyl)oxy)phenyl)-4-(4-sulfamoylbenzyl)-1H-pyrazol-1-yl)thiazole-4-carboxylic acid; MS (ES) 576.9 (M + H)+ LCMS RT = 1.02 min.


name: 2-(4-(4-sulfamoylbenzyl)-3-(3-((tetrahydrofuran-2-yl)methoxy)phenyl)-1H-pyrazol-1-yl)thiazole-4-carboxylic acid; MS (ES) 540.9 (M + H)+ LCMS RT = 0.76 min.


name: 2-(3-(3-phenoxyphenyl)-4-(4-sulfamoylbenzyl)-1H-pyrazol-1-yl)thiazole-4-carboxylic acid; MS (ES) 532.9(M + H)+ LCMS RT = 0.98 min.


name: 2-(5-(cyclopropylmethyl)-3-(4-fluoro-3-((5-(trifluoromethyl)furan-2-yl)methoxy)phenyl)-4-(3-fluoro-4-sulfamoylbenzyl)-1H-pyrazol-1-yl)thiazole-4-carboxylic acid; MS (ES) 694.9 (M + H)+, LCMS RT = 1.20 min.


name: 2-(5-(pyridin-3-yl)-4-(4-sulfamoylbenzyl)-1H-pyrazol-1-yl)thiazole-4-carboxylic acid; MS (ES) 442 (M + H)+ LCMS RT 0.64 min.


name: 2-(5-(cyclopropylmethyl)-3-(4'',5-difluoro-[1,1''-biphenyl]-3-yl)-4-(4-sulfamoylbenzyl)-1H-pyrazol-1-yl)thiazole-4-carboxylic acid; MS (ES) 607 (M + H)+ LCMS RT 1.35 min.


name: 2-(3-(3'',5''-difluoro-6-methyl-[1,1''-biphenyl]-3-yl)-4-(4-sulfamoylbenzyl)-1H-pyrazol-1-yl)thiazole-4-carboxylic acid; MS (ES) 569.6 (M + H)+; LCMS RT = 1.24 min.


name: 2-(3-(3'',4''-difluoro-6-methyl-[1,1''-biphenyl]-3-yl)-4-(4-sulfamoylbenzyl)-1H-pyrazol-1-yl)thiazole-4-carboxylic acid; MS (ES) 567.9 (M + H)+; LCMS RT = 1.20 min.


name: 2-(3-(4''-fluoro-3'',6-dimethyl-[1,1''-biphenyl]-3-yl)-4-(4-sulfamoylbenzyl)-1H-pyrazol-1-yl)thiazole-4-carboxylic acid; MS (ES) 563.9 (M + H)+; LCMS RT = 1.25 min.


name: 2-(3-(3''-fluoro-4''-methoxy-6-methyl-[1,1''-biphenyl]-3-yl)-4-(4-sulfamoylbenzyl)-1H-pyrazol-1-yl)thiazole-4-carboxylic acid; MS (ES) 579.6 (M + H)+; LCMS RT = 1.18 min.


name: 2-(4-(4-sulfamoylbenzyl)-3-(3'',5'',6-trimethyl-[1,1''-biphenyl]-3-yl)-1H-pyrazol-1-yl)thiazole-4-carboxylic acid; MS (ES) 559.9 (M + H)+; LCMS RT = 1.29 min.


name: 2-(3-(3''-cyano-4'',6-dimethyl-[1,1''-biphenyl]-3-yl)-4-(4-sulfamoylbenzyl)-1H-pyrazol-1-yl)thiazole-4-carboxylic acid; MS (ES) 570.9 (M + H)+; LCMS RT = 1.16 min.


name: 2-(3-(3''-fluoro-6-methyl-[1,1''-biphenyl]-3-yl)-4-(4-sulfamoylbenzyl)-1H-pyrazol-1-yl)thiazole-4-carboxylic acid; MS (ES) 549.6 (M + H)+; LCMS RT = 1.18 min.


name: 2-(3-(4''-fluoro-6-methyl-[1,1''-biphenyl]-3-yl)-4-(4-sulfamoylbenzyl)-1H-pyrazol-1-yl)thiazole-4-carboxylic acid; MS (ES) 549.6 (M + H)+; LCMS RT = 1.16 min.


name: 2-(5-(cyclopropylmethyl)-3-(3-isopropoxyphenyl)-4-(4-sulfamoylbenzyl)-1H-pyrazol-1-yl)thiazole-4-carboxylic acid; MS (ES) 552.6 (M + H)+; LCMS RT = 0.98 min.


name: 2-(5-(cyclopropylmethyl)-3-(3''-fluoro-5-methyl-[1,1''-biphenyl]-3-yl)-4-(4-sulfamoylbenzyl)-1H-pyrazol-1-yl)thiazole-4-carboxylic acid; MS (ES) 603.7 (M + H)+; LCMS RT = 1.26 min.


name: 2-(5-(cyclopropylmethyl)-3-(4''-fluoro-5-methyl-[1,1''-biphenyl]-3-yl)-4-(4-sulfamoylbenzyl)-1H-pyrazol-1-yl)thiazole-4-carboxylic acid; MS (ES) 603.4 (M + H)+; LCMS RT = 1.26 min.


name: 2-(3-(6-fluoro-[1,1''-biphenyl]-3-yl)-4-(4-sulfamoylbenzyl)-1H-pyrazol-1-yl)thiazole-4-carboxylic acid; MS (ES) 544.0 (M + H)+; LCMS RT = 1.18 min.


name: 2-(3-(6-fluoro-3'',4''-dimethyl-[1,1''-biphenyl]-3-yl)-4-(4-sulfamoylbenzyl)-1H-pyrazol-1-yl)thiazole-4-carboxylic acid; MS (ES) 562.9 (M + H)+; LCMS RT = 1.23 min.


name: 2-(4-(4-sulfamoylbenzyl)-3-(3'',4'',6-trifluoro-[1,1''-biphenyl]-3-yl)-1H-pyrazol-1-yl)thiazole-4-carboxylic acid; MS (ES) 571.0 (M + H)+; LCMS RT = 1.18 min.


name: 2-(3-(4'',6-difluoro-3''-methoxy-[1,1''-biphenyl]-3-yl)-4-(4-sulfamoylbenzyl)-1H-pyrazol-1-yl)thiazole-4-carboxylic acid; MS (ES) 582.9 (M + H)+; LCMS RT = 1.14 min.


name: 2-(3-(3''-methyl-[1,1''-biphenyl]-3-yl)-4-(4-sulfamoylbenzyl)-1H-pyrazol-1-yl)thiazole-4-carboxylic acid; MS (ES) 530.9 (M + H)+; LCMS RT = 1.00 min.


name: 2-(3-(3'',6-difluoro-4''-methyl-[1,1''-biphenyl]-3-yl)-4-(4-sulfamoylbenzyl)-1H-pyrazol-1-yl)thiazole-4-carboxylic acid; MS (ES) 566.9 (M + H)+; LCMS RT = 1.22 min.


name: 2-(3-(3''-methoxy-[1,1''-biphenyl]-3-yl)-4-(4-sulfamoylbenzyl)-1H-pyrazol-1-yl)thiazole-4-carboxylic acid; MS (ES) 546.9 (M + H)+; LCMS RT = 0.89 min.


name: 2-(3-(3-(pyridin-3-yl)phenyl)-4-(4-sulfamoylbenzyl)-1H-pyrazol-1-yl)thiazole-4-carboxylic acid; MS (ES) 517.9 (M + H)+; LCMS RT = 0.82 min.


name: 2-(5-(cyclopropylmethyl)-3-(3'',5-difluoro-[1,1''-biphenyl]-3-yl)-4-(4-sulfamoylbenzyl)-1H-pyrazol-1-yl)thiazole-4-carboxylic acid; MS (ES) 607.0 (M + H)+; LCMS RT = 1.10 min.


name: 2-(3-(3''-amino-[1,1''-biphenyl]-3-yl)-4-(4-sulfamoylbenzyl)-1H-pyrazol-1-yl)thiazole-4-carboxylic acid; MS (ES) 532.0 (M + H)+; LCMS RT = 0.70 min.


name: 2-(5-(cyclopropylmethyl)-3-(4-fluoro-3-(trifluoromethyl)phenyl)-4-(3-fluoro-4-sulfamoylbenzyl)-1H-pyrazol-1-yl)thiazole-4-carboxylic acid (M + H)+ = 599


name: 2-(3-(3-(benzylcarbamoyl)-4-fluorophenyl)-5-(cyclopropylmethyl)-4-(3-fluoro-4-sulfamoylbenzyl)-1H-pyrazol-1-yl)thiazole-4-carboxylic acid: MS (ES) 664.0 (M + H)+, LCMS RT = 1.052 min.


name: PUR6_HUMAN Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase (sprot)

description: A bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase that is encoded in the genome of human.


name: FABP7_HUMAN Fatty acid-binding protein, brain (sprot)

description: A fatty acid-binding protein, brain that is encoded in the genome of human.


name: ADCYA_HUMAN Adenylate cyclase type 10 (sprot)

description: An adenylate cyclase type 10 that is encoded in the genome of human.


name: PRPS1_HUMAN Ribose-phosphate pyrophosphokinase 1 (sprot)

description: A ribose-phosphate pyrophosphokinase 1 that is encoded in the genome of human.


name: ERBB3_HUMAN Receptor tyrosine-protein kinase erbB-3 (sprot)

description: A receptor tyrosine-protein kinase erbB-3 that is encoded in the genome of human.


name: Indole chloropyridinyl-ester derived, 7c


name: Indole chloropyridinyl-ester derived, 7e


name: Indole chloropyridinyl-ester derived, 7f


name: Indole chloropyridinyl-ester derived, 7g


name: Indole chloropyridinyl-ester derived, 7h


name: Indole chloropyridinyl-ester derived, 7i


name: Indole chloropyridinyl-ester derived, 7j


name: Indole chloropyridinyl-ester derived, 7k


name: Indole chloropyridinyl-ester derived, 7l


name: Indole chloropyridinyl-ester derived, 7m


name: Indole chloropyridinyl-ester derived, 9a


name: Indole chloropyridinyl-ester derived, 9b


name: Indole chloropyridinyl-ester derived, 9d


name: Indole chloropyridinyl-ester derived, 9e


name: Indole chloropyridinyl-ester derived, 9f


TAXIFOLIN

A pentahydroxyflavanone that is the 2,3-dihydro derivative of quercetin.


nirmatrelvir

An azabicyclohexane that is (1R,5S)-3-azabicyclo[3.1.0]hexane substituted by {(1S)-1-cyano-2-[(3S)-2-oxopyrrolidin-3-yl]ethyl}aminoacyl, 3-methyl-N-(trifluoroacetyl)-L-valinamide, methyl and methyl groups at positions 2S, 3, 6 and 6, respectively. It is the first orally administered inhibitor of SARS-CoV-2 main protease developed by Pfizer and used in combination with ritonavir for the treatment of COVID-19.


name: MLP3B_HUMAN Microtubule-associated proteins 1A/1B light chain 3B (sprot)

description: A microtubule-associated proteins 1A/1B light chain 3B that is encoded in the genome of human.


name: 7-[[5-[(3R)-3-(methv iamino)-1-piperidyl]-2-pyridyl] amino]-4-(1-methylpyrrolo [2,3-b]pyridin-4-yl)isoindolin-1-one


name: 7-[[5-(4-Hydroxy-1-piperidyl)-2-pyridyl]amino methylpyrrolo [2,3-b]pyridin-4-yl)-2,3-dihydropyrrolo [3,4-c]pyridin-1-one


name: 4-(7-Methylimidazo [1,2-a]pyridin-3-yl)-7-[(5-methylsulfony 1-2-pyridyl)amino] isoindolin-1-one


name: 4-(7-Methylimidazo [1,2-a]pyridin-3-yl)-7-[(5-morpholino-2-pyridyl)amino 1-2,3-dihydropyrrolo [3,4-c]pyridin-1-one


name: 7-[[5-(4-hydroxy-1-piperidyl)-2-pyridyl]-amino]-4-[7-(2-methoxyethyl-amino)imidazo [1,2-a]pyridin-3-yl]isoindolin-1-one Formic acid salt


name: 4-(7-Fluoroimidazo [1,2-a]pyridin-3-yl)-7-[[5-[2-methoxyethyl (methyl)amino]-2-pyridyl]amino] isoindolin-1-one


name: Formic acid salt 4-(7-fluoroimidazo [1,2-a]pyridin-3-yl)-7-[[5-(3-morpholino-1-piperidyl)-2-pyridyl]amino] isoindolin-1-one


name: 7-[[5-[(2R)-2-[(cyclopropyla mino)methyl] morpholin-4-yl]-2-pyridyl] amino]-4-(7-fluoroimidazo [1,2-a]pyridin-3-yl)isoindolin-1-one


name: 7-[[5-[3-[[Cyclopropyl (methyl)amino] methyl]-3-hydroxy-1-piperidyl]-2-pyridyl]amino] 4-(7-fluoroimidazo [1,2-a]pyridin-3-yl)isoindolin-1-one


name: 7-[[5-[(2S)-2-[[cyclopropyl (methyl)amino] methyl]morph olin-4-yl]-2-pyridyl]amino] 4-(7-fluoroimidazo [1,2-a]pyridin-3-yl)isoindolin-1-one


name: 4-(7-Fluoroimidazo [1,2-a]pyridin-3-yl)-7-[[5-(1-oxa-4,8-diazaspiro[5.5] undecan-8-yl)-2-pyridyl]amino] isoindolin-1-one


name: 7-[[5-[6-(dimethylami-no)-l,4-oxazepan-4-yl]-2-pyridyl]amino]-4-(7-fluoroimidazo [1,2-a]pyridin-3-yl)isoindolin-1-one Formic acid salt


name: 7-[[6-[(dimethylamino)-methyl]-5-[(3R)-3-methylmorpho-lin-4-yl J-2-pyridyl]amino]-4-(7-fluoroimidazo [1,2-a]pyridin-3-yl)isoindolin-1-one Formic acid salt


name: 7-[[6-[(dimethylamino)-methyl]-5-[(2S)-2-methylmorpho-lin-4-yl]-2-pyridyl]amino]-4-(7-fluoroimidazo [1,2-a]pyridin-3-yl)isoindolin-1-one Bis formic acid salt


name: 7-[[6-[(dimethylamino)-methyl]-5-(4-oxa-7-azaspiro[2.5] octan-7-yl)-2-pyridyl]amino]-4-(7-fluoroimidazo [1,2-a]pyridin-3-yl)isoindolin-1-one Formic acid salt


name: 7-[[6-[(dimethylamino)-methyl]-5-(4-methyl-5-oxo-1, 4-diazepan-1-yl)-2-pyridyl]amino]-4-(7-fluoroimidazo [1,2-a]pyridin-3-yl)isoindolin-1-one Formic acid salt


name: 7-[[6-[(dimethylamino)-methyl]-5-(4-hydroxy-4-methyl-1-piperidyl)-2-pyridyl]amino]-4-(7-fluoroimidazo [1,2-a]pyridin-3-yl)isoindolin-1-one Formic acid salt


name: 7-[[8-(dimethylami-no)-5,6,7,8-tetrahydroquin-olin-2-yl]amino]-4-(7-fluoroimidazo [1,2-a]pyridin-3-yl)isoindolin-1-one Formic acid salt


name: 4-(1-Methylpyrrolo [2,3-b]pyridin-4-yl)-7-[[6-(pyrrolidin-1-ylmethyl)-5-tetraln drofuran-3-yl-2-pyridyl] amino]-2,3-dihydropyrrolo [3,4-c]pyridin-1-one


name: 4-(7-(Difluoromethv l)-8-fluoroimidazo [1,2-a]pyridin-3-yl)-7-((5-((2,2-dimethylpipera zin-1-yl)methyl) pyridin-2-yl)amino)isoin-dolin-1-one


name: 7-[[6-[(isopropylamino)-methyl]-5-tetrahydropy-ran-4-yl-2-pyridyl]amino]-4-(1-methylpyrrolo [2,3-b]pyridin-4-yl)-2,3-dihydropyrrolo [3,4-c]pyridin-1-one Formic acid salt


name: 7-[[6-[(dimethylamino)-methyl]-5-tetrahydropyran-4-yl-2-pyridyl]amino]-4-[l-methylpyrrolo [2,3-b]pyridin-4-yl)-2,3-dihydropyrrolo [3,4-c]pyridin-1-one Formic acid salt


name: 4-(7-fluoroimidazo [1,2-a]pyridin-3-yl)-7-[[6-[(isopropylamino)-methyl]-5-tetrahydropyran-4-yl-2-pyridyl]amino] isoindolin-1-one Formic acid salt


name: 7-[[6-[(cyclopropyl methylamino) methyl]-5-tetrahydrofuran-3-yl-2-pyridyl]amino]-4-(7-fluoroimidazo [1,2-a]pyridin-3-yl)isoindolin-1-one Formic acid salt


name: 7-1(6-[(dimethylamino)-methyl (-5-[4-hydroxy-4-(methoxymeth-yl)-1-piperidyl]-2-pyridyl]amino]-4-(1-methylpyrrolo [2,3-b]pyridin-4-yl)-2,3-dihydropyrrolo [3,4-c]pyridin-1-one Formate salt


name: STING_MOUSE Stimulator of interferon genes protein (sprot)

description: A transmembrane protein 173 that is encoded in the genome of mouse.


ENPL_CANLF Endoplasmin (sprot)

An endoplasmin that is encoded in the genome of dog.


name: US11034691, CYM generic formula 52356 IB


name: US11034691, CYM generic formula 52548 IB


name: US11034691, CYM generic formula 52610 IB


name: US11034691, CYM generic formula 52667 IB


name: US11034691, CYM generic formula 52679 IB


name: US11034691, CYM generic formula 52717 IB


name: US11034691, CYM generic formula 52725 IB


name: US11034691, CYM generic formula 52729 IB


name: US11034691, CYM generic formula 52741 IA


name: US11034691, CYM generic formula 52742 IA


name: US11034691, CYM generic formula 52205 IB


name: US11034691, CYM generic formula 52310 IB


name: US11034691, CYM generic formula 52311 IB


name: US11034691, CYM generic formula 52312 IB


name: US11034691, CYM generic formula 52313 IB


name: US11034691, CYM generic formula 52406 IB


name: US11034691, CYM generic formula 52451 IB


name: US11034691, CYM generic formula 52480 IB


name: US11034691, CYM generic formula 52636 IB


name: US11034691, CYM generic formula 52648 IB


name: N-(8-amino-6-(1-methyl-1H-pyrazol-4-yl)-2,7-naphthyridin-3-yl)-2-methylcyclopropanecarboxamide (3:1 ratio of trans/cis)


name: trans-N-(8-amino-6-(4-ethylpyridin-3-yl)-2,7-naphthyridin-3-yl)-2-(methoxymethyl) cyclo propane carboxamide


name: FXR1_HUMAN RNA-binding protein FXR1 (sprot)

description: An RNA-binding protein FXR1 that is encoded in the genome of human.


name: FXR1_MOUSE RNA-binding protein FXR1 (sprot)

description: An RNA-binding protein FXR1 that is encoded in the genome of mouse.


name: FXR1_RAT RNA-binding protein FXR1 (sprot)

description: An RNA-binding protein FXR1 that is encoded in the genome of rat.


name: VMAT2_HUMAN Synaptic vesicular amine transporter (sprot)

description: A synaptic vesicular amine transporter that is encoded in the genome of human.


name: SUMO1_HUMAN Small ubiquitin-related modifier 1 (sprot)

description: A small ubiquitin-related modifier 1 that is encoded in the genome of human.


name: SUMO2_HUMAN Small ubiquitin-related modifier 2 (sprot)

description: A small ubiquitin-related modifier 2 that is encoded in the genome of human.


name: METK2_HUMAN S-adenosylmethionine synthase isoform type-2 (sprot)

description: An S-adenosylmethionine synthetase isoform type-2 that is encoded in the genome of human.


name: 1-(2-chlorophenyl)-4-(3-hydroxy-3-methylpyrrolidin-1-yl)-7-(trifluoro-methyl) pyrido[2,3-d]pyrimidin-2(1H)-one, single unknown enantiomer


name: 1-(2-Bromophenyl)-7-cyclopropyl-4-(methylamino)-2-oxo-1,2-dihydro-quinazoline-6-carbonitrile, single unknown atropisomer


name: (S)-1-(1-(1H-imidazol-4-yl)ethyl)-4-(methylamino)-7-(trifluoromethyl)-quinazolin-2(1H)-one, Single unknown enantiomer


name: (R)-1-(1-(1H-imidazol-4-yl)ethyl)-4-(methylamino)-7-(trifluoromethyl)quinazolin-2(1H)-one, single unknown enantiomer


ANO1_HUMAN Anoctamin-1 (sprot)

An anoctamin-1 that is encoded in the genome of human.


lufotrelvir

An indolecarboxamide resulting from the formal condensation of the carboxy group of 4-methoxy-1H-indole-2-carboxylic acid with the primary amino group of N-[(2S)-3-oxo-1-[(3S)-2-oxopyrrolidin-3-yl]-4-(phosphonooxy)butan-2-yl]-L-leucinamide. It is the phosphate prodrug of PF-00835231, an anticoronaviral agent.


name: A0EPY1_PNEJI Dihydrofolate reductase (trembl)


name: GGTI2418; GGTI 2418; PTX-100; PTX 100; PTX100;Geranylgeranyl transferase inhibitor-2148


name: Synthesis of 2-(aminomethyl)quinolin-4(1H)-one hydrochloride


name: Synthesis of 2-(aminomethyl)-6-bromoquinolin-4(1H)-one hydrochloride


name: Synthesis of 2-(aminomethyl)-6-ethynvlquinolin-4(1H)-one hydrochloride


name: Synthesis of 2-(aminomethyl)-6-phenylquinolin-4(1H)-one hydrochloride


name: Synthesis of 2-(aminomethyl)-6-(1-phenyl-1H-1,2,3-triazol-4-yl)quinolin-4(1H)-one hydrochloride


name: Synthesis of 2-(aminomethyl)-6-(phenylethynyl)quinolin-4(1H)-one hydrochloride


name: Synthesis of 2-(aminomethyl)-6-(1H-pyrazol-1-yl)quinolin-4(1U)-one hydrochloride


name: Synthesis of 2-(aminomethyl)-6-methoxyquinolin-4(1H)-one hydrochloride


name: Synthesis of 2-(aminomethyl)-6-(4-fluorophenyl)quinolin-4(1H)-one hydrochloride


name: Synthesis of 2-(aminomethyl)-6-phenoxyquinolin-4(1H)-one hydrochloride


name: Synthesis of 2-(aminomethyl)-6-(pyrimidin-5-yl)quinolin-4(1H)-one hydrochloride


name: Synthesis of 2-(aminomethyl)-6-(5-methyl-2-oxopyridin-1(2H)-yl)quinolin-4(1H)-one hydrochloride


name: Synthesis of 2-(aminomethyl)-6-(1-methyl-1H-pyrazol-4-yl)quinolin-4(1H)-one hydrochloride


name: Synthesis of 2-(aminomethyl)-[6,8'-biquinolin]-4(1H)-one hydrochloride


name: Synthesis of 2-(aminomethyl)-6-(5-(benzyloxy)pyridin-3-yl)quinolin-4(1H)-one hydrochloride


name: Synthesis of 2-(aminomethyl)-6-(2-chloro-4-fluorophenyl)quinolin-4(1H)-one hydrochloride


name: Synthesis of 2-(aminomethyl)-6-(3-fluoro-4-methoxyphenyl)quinolin-4(1H)-one hydrochloride


name: Synthesis of 2-(aminomethyl)-6-(6-(trifluoromethyl)pyridin-3-yl)quinolin-4(1H)-one hydrochloride


name: Synthesis of 2-(aminomethyl)-6-(2-(trifluoromethyl)pyrimidin-5-yl)quinolin-4(1H)-one hydrochloride


name: Synthesis of 2-(aminomethyl)-6-(2-methoxyethoxy)quinolin-4(1)-one hydrochloride


name: 4-sulfamoylbenzoic acid (CAS-RN 138-41-0)


name: 3-((S)-2-Benzyloxycarbonylamino-3-methyl-butyrylamino)-5-fluoro-4-oxo-pentanoic acid methyl ester


compound 13b [PMID: 32198291]

A secondary carboxamide resulting from the formal condensation of the carboxy group of (2S)-2-{3-[(tert-butoxycarbonyl)amino]-2-oxopyridin-1(2H)-yl}-3-cyclopropylpropanoic acid with the primary amino group of (2R,3S)-3-amino-N-benzyl-2-hydroxy-4-[(3S)-2-oxopyrrolidin-3-yl]butanamide. It is an inhibitor of SARS-CoV-2 main protease.


PYROMELLITIC ACID

A tetracarboxylic acid that is benzene substituted by four carboxy groups at positions 1, 2, 4 and 5 respectively.


teicoplanin

A complex mixture of related natural products isolated from the fermentation broth of a strain of Actinoplanes teichomyceticus comprising five major components (teicoplanin A2-1 through A2-5), a hydrolysis component (teicoplanin A3-1), and four minor components (teicoplanin RS-1 through RS-4). An antibiotic with a similar spectrum of activity to vancomycin, it is used to treat serious Gram-positive bacterial infections, including methicillin-resistant Staphylococcus aureus and Enterococcus faecalis.


thiomersal

An alkylmercury compound (approximately 49% mercury by weight) used as an antiseptic and antifungal agent.


abacavir

A 2,6-diaminopurine that is (1S)-cyclopent-2-en-1-ylmethanol in which the pro-R hydrogen at the 4-position is substituted by a 2-amino-6-(cyclopropylamino)-9H-purin-9-yl group. A nucleoside analogue reverse transcriptase inhibitor (NRTI) with antiretroviral activity against HIV, it is used (particularly as the sulfate) with other antiretrovirals in combination therapy of HIV infection.


tenofovir

A member of the class of phosphonic acids that is methylphosphonic acid in which one of the methyl hydrogens is replaced by a [(2R)-1-(6-amino-9H-purin-9-yl)propan-2-yl]oxy group. An inhibitor of HIV-1 reverse transcriptase, the bis(isopropyloxycarbonyloxymethyl) ester (disoproxil ester) prodrug is used as the fumaric acid salt in combination therapy for the treatment of HIV infection.


A tripeptide composed of N-acetylleucyl, leucyl and norleucinal residues joined in sequence.


PHENETHYLISOTHIOCYANATE

An isothiocyanate having a phenethyl group attached to the nitrogen. It is a naturally occurring compound found in some cruciferous vegetables (e.g. watercress) and is known to possess anticancer properties.


A tripeptide that is L-seryl-L-valyl-L-leucine in which the amino group at the N-terminal is substituted by a tert-butoxycarbonyl group and the carboxy group at the C-terminal is substituted by a {(2S,3E)-5-ethoxy-5-oxo-1-[(3S)-2-oxopyrrolidin-3-yl]pent-3-en-2-yl}amino group. It is a 3C-like protease inhibitor of MERS-CoV and SARS-CoV.


name: N-[4-methyl-1-oxo-1-(1-oxohexan-2-ylamino)pentan-2-yl]carbamic acid (phenylmethyl) ester


A PYR-41 that has (Z)-configuration.


DIHYDROCELASTROL

A pentacyclic triterpenoid with formula C29H40O4, originally isolated from the root bark of Tripterygium regelii.


oritavancin

A semisynthetic glycopeptide used (as its bisphosphate salt) for the treatment of acute bacterial skin and skin structure infections caused or suspected to be caused by susceptible isolates of designated Gram-positive microorganisms including MRSA.


PENTAGALLOYL GLUCOSE

A galloyl-beta-D-glucose compound having five galloyl groups in the 1-, 2-, 3-, 4- and 6-positions.


FERRUGINOL

An abietane diterpenoid that is abieta-8,11,13-triene substituted by a hydroxy group at positions 12.


A hydroxyflavan  that is 3,4-dihydro-2H-chromene which is substituted at positions 3, 5, and 7 by hydroxy groups, and at position 2 by a 3,4,5-trihydroxyphenyl group.


CATECHIN

Members of the class of hydroxyflavan that have a flavan-3-ol skeleton and its substituted derivatives.


dihydroergotamine

Ergotamine in which a single bond replaces the double bond between positions 9 and 10. A semisynthetic ergot alkaloid with weaker oxytocic and vasoconstrictor properties than ergotamine, it is used (as the methanesulfonic or tartaric acid salts) for the treatment of migraine and orthostatic hypotension.


ABIETIC ACID

An abietane diterpenoid that is abieta-7,13-diene substituted by a carboxy group at position 18.


Ac-Tyr-Val-Ala-Asp-chloromethylketone

A tetrapeptide composed of L-tyrosine, L-valine, L-alanine, and L-aspartic acid joined in sequence by peptide linkages and in which the amino terminus in substituted by an acetyl group and the carboxy terminus is substituted by a chloromethyl group.


name: P3C2G_HUMAN Phosphatidylinositol 3-kinase C2 domain-containing subunit gamma (sprot)

description: A phosphatidylinositol 3-kinase C2 domain-containing subunit gamma that is encoded in the genome of human.


name: PI4KA_HUMAN Phosphatidylinositol 4-kinase alpha (sprot)

description: A phosphatidylinositol 4-kinase alpha that is encoded in the genome of human.


name: Synthesis of (2S)-1-((4R,7S)-7-((2R,3S,4R,11 S,12R)-12-benzyl-3,11-dihydroxy-4-methyltetradecan-2-yl)-2-hydroxy-4-methyl-3-oxooxepane-2-carbonyl)piperidine-2-carboxylic acid C-11 lactone


name: Q4E4E1_TRYCC Glucokinase 1, putative (trembl)


POLG_DEN26 Genome polyprotein (sprot)

A dengue virus genome polyprotein that is encoded in the genome of Dengue virus 2 Thailand/16681/84.


name: The Preparation of (+-)(Z)-N-(3-bromo-4-fluorophenyl)-N'-hydroxy-4-((4-(thio-methyl sulfoxide imine)butyl)amino)-1,2,5-oxadiazole-3-carboxamidine


name: The Preparation of (+-) (Z)-N-(3-bromo-4-fluorophenyl)-N'-hydroxy-4-((2-(thio-phenyl sulfoxide imine)ethyl)amino)-1,2,5-oxadiazole-3-carboxamidine


name: The Preparation of (+-)(Z)-N-(3-pentafluoride thiophenyl)-N'-hydroxy-4-((2-(thio-methyl sulfoxide imine)ethyl)amino)-1,2,5-oxadiazole-3-carboxamidine


name: The Preparation of (+-) (Z)-N-(3-bromo-4-fluorophenyl)-N'-hydroxy-4-((3-(thio-methyl sulfoxide cyano amine)propyl)amino)-1,2,5-oxadiazole-3-carboxamidine


name: The Preparation of (+-) (Z)-N-(3-bromo-4-fluorophenyl)-N'-hydroxy-4-((4-(thio-methyl sulfoxide cyano amine)butyl)amino)-1,2,5-oxadiazole-3-carboxamidine


name: The Preparation of (+-)(Z)-N-(3-chloro-4-fluorophenyl)-N'-hydroxy-4-((4-(thio-methyl sulfoxide cyano amine)butyl)amino)-1,2,5-oxadiazole-3-carboxamidine


name: The Preparation of (+-)(Z)-N-(3-Br-4-fluorophenyl)-N'-hydroxy-4-((2-(thio-methyl sulfoxide cyano amine) ethyl) amino)-1,2,5-oxadiazole-3-isobutyrate


name: The Preparation of (+-)(Z)-N-(3-bromo-4-fluorophenyl)-N'-hydroxy-4-((2-(thio-methyl sulfoxide cyano amine)ethyl)amino)-1,2,5-oxadiazole-3-trimethyl acetate


name: UBP19_HUMAN Ubiquitin carboxyl-terminal hydrolase 19 (sprot)

description: A ubiquitin carboxyl-terminal hydrolase 19 that is encoded in the genome of human.


name: Synthesis of N-(2-aminoethyl)-4-[[2-(5-chloro-2-fluoro-phenyl)-5-isopropyl-4-pyridyl]amino] pyridine-3-carboxamide


name: BMP10_HUMAN Bone morphogenetic protein 10 (sprot)

description: A bone morphogenetic protein 10 that is encoded in the genome of human.


name: PKNX1_HUMAN Homeobox protein PKNOX1 (sprot)

description: A homeobox protein PKNOX1 that is encoded in the genome of human.


name: US11096924, DASH-inhibitors (formerly 3102 A 2C)


name: RPGF3_HUMAN Rap guanine nucleotide exchange factor 3 (sprot)

description: A Rap guanine nucleotide exchange factor 3 that is encoded in the genome of human.


name: RPGF4_HUMAN Rap guanine nucleotide exchange factor 4 (sprot)

description: A Rap guanine nucleotide exchange factor 4 that is encoded in the genome of human.


THYMIDINE MONOPHOSPHATE

The neutral species of thymidine 5'-monophosphate (2'-deoxythymidine 5'-monophosphate).


name: GNPTA_HUMAN N-acetylglucosamine-1-phosphotransferase subunits alpha/beta (sprot)

description: An N-acetylglucosamine-1-phosphotransferase subunits alpha/beta that is encoded in the genome of human.


tarocin B

A member of the class of benzimidazoles that is the amide obtained by formal condensation of the carboxy group of 3-(2-cyclohexylbenzimidazol-1-yl)propanoic acid with the amino group of (1R,2R,4R)-1,7,7-trimethylbicyclo[2.2.1]heptan-2-amine. An inhibitor of teichoic acid biosynthesis.


tarocin A2

A member of the class of oxazolidinones that is oxazolidin-2-one substituted at positions 3, 4 and 5 by 3-(isoquinolin-4-ylmethyl)carbamoyl, methyl and 3-(trifluoromethyl)phenyl groups respectively. An inhibitor of teichoic acid biosynthesis.


tarocin A1

A member of the class of oxazolidinones that is oxazolidin-2-one substituted at positions 3, 4 and 5 by 3-(isoquinolin-4-yl)propanoyl, methyl and 3,5-bis(trifluoromethyl)phenyl groups respectively. An inhibitor of teichoic acid biosynthesis.


tarocin A

A member of the class of oxazolidinones that is oxazolidin-2-one substituted at positions 3, 4 and 5 by (naphthalen-1-yl)acetyl, methyl and 3,5-bis(trifluoromethyl)phenyl groups respectively. An inhibitor of teichoic acid biosynthesis.


trametinib

A pyridopyrimidine that is used (as its dimethyl sulfoxide addition compound) for the treatment of patients with unresectable or metastatic melanoma with BRAF V600E or V600K mutations, and who have not received prior BRAF inhibitor treatment.


binimetinib

A member of the class of benzimidazoles that is 1-methyl-1H-benzimidazole which is substituted at positions 4, 5, and 6 by fluorine, (4-bromo-2-fluorophenyl)nitrilo, and N-(2-hydroxyethoxy)aminocarbonyl groups, respectively. It is a MEK1 and MEK2 inhibitor (IC50= 12 nM). Approved by the FDA for the  treatment of patients with unresectable or metastatic melanoma with a BRAF V600E or V600K mutation in combination with encorafenib.


avutometinib

A member of the class of coumarins that is 4-methyl-7-[(pyrimidin-2-yl)oxy]coumarin carrying an additional [2-[(methylaminosulfonyl)amino]-3-fluoropyridin-4-yl]methyl substituent at position 3.


POLG_DEN1W Genome polyprotein (sprot)

A dengue virus genome polyprotein that is encoded in the genome of Dengue virus 1 Nauru/West Pac/1974.


remdesivir triphosphate

An organic triphosphate that is GS-441524 in which the 5'-hydroxy group has been replaced by a triphosphate group. It is the active metabolite of remdesivir.


TSP1_HUMAN Thrombospondin-1 (sprot)

A thrombospondin-1 that is encoded in the genome of human.


name: HTRA2_HUMAN Serine protease HTRA2, mitochondrial (sprot)

description: A serine protease HTRA2, mitochondrial that is encoded in the genome of human.


name: HTRA3_HUMAN Serine protease HTRA3 (sprot)

description: A serine protease HTRA3 that is encoded in the genome of human.


CTRB1_HUMAN Chymotrypsinogen B (sprot)

A chymotrypsinogen B that is encoded in the genome of human.


etrasimod

An organic heterotricyclic compound that is 1,2,3,4-tetrahydrocyclopenta[b]indole substituted by carboxymethyl and [4-cyclopentyl-3-(trifluoromethyl)phenyl]methoxy groups at positions 3R and 7, respectively. It is a potent and functional antagonist of the sphingosine-1-phosphate-1 (S1P1) receptor (IC50 = 1.88 nM in CHO cells).


name: BCL6_HUMAN B-cell lymphoma 6 protein (sprot)

description: A B-cell lymphoma 6 protein that is encoded in the genome of human.


name: DEGS1_HUMAN Sphingolipid delta(4)-desaturase DES1 (sprot)

description: A sphingolipid Delta(4)-desaturase DES1 that is encoded in the genome of human.


name: M3K6_HUMAN Mitogen-activated protein kinase kinase kinase 6 (sprot)

description: A mitogen-activated protein kinase kinase kinase 6 that is encoded in the genome of human.


name: ATF4_HUMAN Cyclic AMP-dependent transcription factor ATF-4 (sprot)

description: A cyclic AMP-dependent transcription factor ATF-4 that is encoded in the genome of human.


name: RXRB_HUMAN Retinoic acid receptor RXR-beta (sprot)

description: A retinoic acid receptor RXR-beta that is encoded in the genome of human.


name: Preparation of Methyl 4-((4-methyl-1-((2-(piperidin-1-yl)thiazol-4-yl)methyl)-1H-pyrrole-2-carboxamido)methyl)benzoate


name: DNM1L_HUMAN Dynamin-1-like protein (sprot)

description: A dynamin-1-like protein that is encoded in the genome of human.


name: Preparation of Methyl 3-((4-methyl-1-((2-(piperidin-1-yl)thiazol-4-yl)methyl)-1H-pyrrole-2-carboxamido)methyl)benzoate


name: Preparation of Ethyl (3-methylpiperidine-1-carbonothioyl)carbamate


name: Preparation of Ethyl 2-(2-methylpiperidin-1-yl)thiazole-4-carboxylate


name: Preparation of Ethyl 5-methyl-1-((2-(piperidin-1-yl)thiazol-4-yl)methyl)-1H-pyrrole-2-carboxylate


name: Preparation of Methyl 4-(4-methyl-1-((2-(pyridin-3-yl)thiazol-4-yl)methyl)-1H-pyrrole-2-carboxamido)benzoate


name: Preparation of Ethyl 4-nitro-1-((2-(piperidin-1-yl)thiazol-4-yl)methyl)-1H-pyrrole-2-carboxylate


name: Preparation of Methyl 4-(1-((2-(3-fluoropiperidin-1-yl)thiazol-4-yl)methyl)-4-methyl-1H-pyrrole-2-carboxamido)benzoate


name: Preparation of Methyl 4-(1-((2-(dimethylamino)thiazol-4-yl)methyl)-4-methyl-1H-pyrrole-2-carboxamido)benzoate


name: Preparation of Methyl 4-(1-((2-(1H-pyrazol-4-yl)thiazol-4-yl)methyl)-4-methyl-1H-pyrrole-2-carboxamido)benzoate


name: Preparation of Methyl 4-phenyl-1-((2-(piperidin-1-yl)thiazol-4-yl)methyl)-1H-pyrrole-2-carboxylate


name: Preparation of Methyl 4-(1-((2-(cyclohex-1-en-1-yl) thiazol-4-yl)methyl)-4-methyl-1H-pyrrole-2-carboxamido)benzoate


name: Preparation of 4-(4-(1-methoxyethyl)-1-((2-(piperidin-1-yl)thiazol-4-yl)methyl)-1H-pyrrole-2-carboxamido)benzoic Acid


name: Preparation of 4-(1-((2-cyclohexylthiazol-4-yl)methyl)-4-methyl-1H-pyrrole-2-carboxamido)benzoic Acid


name: Preparation of 4-bromo-1-((2-(piperidin-1-yl)thiazol-4-yl)methyl)-1H-pyrrole-2-carboxylic Acid


name: Preparation of 4-(4-(1-hydroxyethyl)-1-((2-(piperidin-1-yl)thiazol-4-yl)methyl)-1H-pyrrole-2-carboxamido)benzoic Acid


name: Preparation of Ethyl 6-(piperidin-1-yl)picolinate


name: TMPS6_HUMAN Transmembrane protease serine 6 (sprot)

description: A transmembrane protease serine 6 that is encoded in the genome of human.


name: CLCN2_HUMAN Chloride channel protein 2 (sprot)

description: A chloride channel protein 2 that is encoded in the genome of human.


name: CLIC1_HUMAN Chloride intracellular channel protein 1 (sprot)

description: A chloride intracellular channel protein 1 that is encoded in the genome of human.


name: ARBK2_HUMAN G protein-coupled receptor kinase 3 (sprot)

description: A G protein-coupled receptor kinase 3 that is encoded in the genome of human.


6-deoxyinosine 5'-phosphate

The 5'-monophosphate of 6-deoxyinosine.


name: IKZF2_HUMAN Zinc finger protein Helios (sprot)

description: A zinc finger protein Helios that is encoded in the genome of human.


name: IKZF1_HUMAN DNA-binding protein Ikaros (sprot)

description: A DNA-binding protein Ikaros that is encoded in the genome of human.


name: LUCI_LUCMI Luciferin 4-monooxygenase (sprot)


name: IPSP_HUMAN Plasma serine protease inhibitor (sprot)

description: A plasma serine protease inhibitor that is encoded in the genome of human.


name: PTPB_MYCTU Triple specificity protein phosphatase PtpB (sprot)


name: MOK_HUMAN MAPK/MAK/MRK overlapping kinase (sprot)

description: A MAPK/MAK/MRK overlapping kinase that is encoded in the genome of human.


name: DYL2_HUMAN Dynein light chain 2, cytoplasmic (sprot)

description: A dynein light chain 2, cytoplasmic that is encoded in the genome of human.


LYAM2_HUMAN E-selectin (sprot)

An E-selectin that is encoded in the genome of human.


laduviglusib

A member of the class of aminopyrimidines that is 2-aminopyrimidine substituted at positions N2, 5 and 6 by (5-cyanopyridin-2-yl)ethyl, 4-methylimidazol-2-yl and 2,4-dichlorophenyl groups respectively.


name: NPT2A_HUMAN Sodium-dependent phosphate transport protein 2A (sprot)

description: A sodium-dependent phosphate transport protein 2A that is encoded in the genome of human.


name: LCLT1_HUMAN Lysocardiolipin acyltransferase 1 (sprot)

description: A lysocardiolipin acyltransferase 1 that is encoded in the genome of human.


name: A0A8C0LZB8_CANLF receptor protein-tyrosine kinase (trembl)


sinefungin

An adenosine that is the the delta-(5'-adenosyl) derivative of ornithine.


name: US11229631, Example 45 Diastereoisomer 2


name: US11229631, Example 46 Diastereoisomer 2


UROM_HUMAN Uromodulin (sprot)

A uromodulin that is encoded in the genome of human.


name: KI18A_HUMAN Kinesin-like protein KIF18A (sprot)

description: A kinesin-like protein KIF18A that is encoded in the genome of human.


name: G1SGC5_RABIT Serine/threonine-protein kinase ATR (trembl)


name: UBP14_HUMAN Ubiquitin carboxyl-terminal hydrolase 14 (sprot)

description: A ubiquitin carboxyl-terminal hydrolase 14 that is encoded in the genome of human.


name: KGP_TOXGO cGMP-dependent protein kinase (sprot)


A member of the class of aminopyrimidines that is 2,6-diamino-5-chloropyrimidine in which the amino groups at positions 2 and 6 are respectively carrying 2-methoxy-4-(morpholin-4-yl)phenyl and 2-(methanesulfonylamino)phenyl substituents. It is an inhibitor of the Parkinson's disease kinase LRRK2.


RASN_HUMAN GTPase NRas (sprot)

A GTPase NRas that is encoded in the genome of human.


name: methyl 4-(((3S,4R)-1-((4-chloro-2-(difluoromethyl) phenyl)sulfonyl)-4-hydroxy-4-(hydroxymethyl) pyrrolidin-3-yl) sulfonyl)benzimidate


name: (3S,4S)-4-((4-chloro-3-fluorophenyl) sulfonyl)-1-((2,4-dichlorophenyl) sulfonyl)-3-(hydroxymethyl) pyrrolidin-3-ol


name: (3R,4S)-1-((2,4-dichlorophenyl) sulfonyl)-4-((3,4-difluorophenyl) sulfonyl)-3-(hydroxymethyl) pyrrolidin-3-ol


name: (3R,4S)-4-((4-chloro-3-fluorophenyl) sulfonyl)-1-((2,4-dichlorophenyl) sulfonyl)-3-(hydroxymethyl) pyrrolidin-3-ol


name: (3R,4S)-1-((2,4-dichlorophenyl) sulfonyl)-4-((4-fluorophenyl) sulfonyl)-3-(hydroxymethyl) pyrrolidin-3-ol


name: 3-chloro-4-(((3R,4S)-4-((4-ethylphenyl) sulfonyl)-3-hydroxy-3-(hydroxymethyl) pyrrolidin-1-yl)sulfonyl)benzo nitrile


name: 3-chloro-4-(((3R,4S)-3-hydroxy-3-(hydroxymethyl)-4-((4-isopropylphenyl) sulfonyl) pyrrolidin-1-yl)sulfonyl)benzo nitrile


name: 3-(((3R,4S)-4-((4-chlorophenyl) sulfonyl)-3-hydroxy-3-(hydroxymethyl) pyrrolidin-1-yl)sulfonyl) picolinonitrile


name: (3R,4S)-1-((2,4-dichlorophenyl) sulfonyl)-4-((3,4-dichlorophenyl) sulfonyl)-3-(hydroxymethyl) pyrrolidin-3-ol


name: (3S,4S)-1-((2,4-dichlorophenyl) sulfonyl)-4-((3,4-dichlorophenyl) sulfonyl)-3-(hydroxymethyl) pyrrolidin-3-ol


SPIKE_SARS2 Spike glycoprotein (sprot)

A protein that is a translation product of the S gene in SARS-CoV-2.


ANO2_HUMAN Anoctamin-2 (sprot)

An anoctamin-2 that is encoded in the genome of human.


name: TRPC3_HUMAN Short transient receptor potential channel 3 (sprot)

description: A short transient receptor potential cation channel TRPC3 that is encoded in the genome of human.


name: (M)-4-(5-Acryloyl-2,5-diazabicyclo[4.1.0]heptan-2-yl)-6-chloro-7-(2-fluorophenyl)-1-(2-isopropyl-4-methylpyridin-3-yl)pyrido[2,3-d]pyrimidin-2(1H)-one (Ex.#s 222, 222-1, and 222-2)


APOA_HUMAN Apolipoprotein(a) (sprot)

An apolipoprotein(a) that is encoded in the genome of human.


name: 4EBP1_HUMAN Eukaryotic translation initiation factor 4E-binding protein 1 (sprot)

description: A eukaryotic translation initiation factor 4E-binding protein 1 that is encoded in the genome of human.


name: TREX1_HUMAN Three-prime repair exonuclease 1 (sprot)

description: A three-prime repair exonuclease 1 that is encoded in the genome of human.


name: TREX1_MOUSE Three-prime repair exonuclease 1 (sprot)

description: A three-prime repair exonuclease 1 that is encoded in the genome of mouse.


name: (3R,4R) and (3S,4S) (-2-[4-(1-cyano-1-methylethyl)phenyl]-3-(2,3-dihydro-1,4-benzodioxin-6-yl)-1-oxo-1,2,3,4-tetrahydroisoquinoline-4-carboxylic acid


name: HSP90_CANAL Heat shock protein 90 homolog (sprot)

description: A heat shock protein HSP 90-alpha that is encoded in the genome of Candida albicans SC5314.


name: B4URF7_I33A0 Polymerase basic protein 2 (trembl)


navitoclax

A N-sulfonylcarboxamide resulting from the formal condensation of the carboxy group of 4-{4-[(4'-chloro-4,4-dimethyl-3,4,5,6-tetrahydro[biphenyl]-2-yl)methyl]piperazin-1-yl}benzoic acid with the amino group of 4-{[(2R)-4-(morpholin-4-yl)-1-(phenylsulfanyl)butan-2-yl]amino}-3-[(trifluoromethyl)sulfonyl]benzenesulfonamide. It is a BH3-mimetic drug which targets the anti-apoptotic B-cell lymphoma-2 (BCL-2) family proteins, including BCL-2, BCL-xL, and BCL-w, and induces apoptosis in cancer cells. Currently under clinical investigation as treatment for solid tumors and hematologic malignancies.


name: PNKP_HUMAN Bifunctional polynucleotide phosphatase/kinase (sprot)

description: A bifunctional polynucleotide phosphatase/kinase that is encoded in the genome of human.


name: PARP6_HUMAN Protein mono-ADP-ribosyltransferase PARP6 (sprot)

description: A protein mono-ADP-ribosyltransferase PARP6 that is encoded in the genome of human.


name: R1A_SARS2 Replicase polyprotein 1a (sprot)


name: RHEB_HUMAN GTP-binding protein Rheb (sprot)

description: A GTP-binding protein Rheb that is encoded in the genome of human.


name: Synthesis of 34(2,6-dichloro-1-(1-propyl-1H-pyrazol-4-yl)-1H-indol-3-yl)thio)benzoic acid


name: Synthesis of 34(2-bromo-6-chloro-1-(1-propyl-1H-pyrazol-4-yl)-1H-indol-3-yl)thio)benzoic acid


name: Synthesis of 34(6-chloro-2-cyano-1-(1-propyl-1H-pyrazol-4-yl)-1H-indol-3-yl)thio)benzoic acid


name: Synthesis of 3-((6-chloro-2-cyclopropyl-1-(1-propyl-1H-pyrazol-4-yl)-1H-indol-3-yl)thio)benzoic acid


name: Synthesis of 34(2,6-dichloro-7-fluoro-1-(1-propyl-1H-pyrazol-4-yl)-1H-indol-3-yl)thio)benzoic acid


name: Synthesis of 3-((6-chloro-2-cyclopropyl-7-fluoro-1-(1-propyl-1H-pyrazol-4-yl)-1H-indol-3-yl)thio)benzoic acid


name: Synthesis of 3-((6-chloro-2-cyclopropyl-7-fluoro-1-(1-propyl-1H-pyrazol-4-yl)-1H-indol-3-yl)thio)-2-fluorobenzoic acid


name: Synthesis of 3-((2,6-dichloro-1-(1-ethyl-1H-pyrazol-4-yl)-7-fluoro-1H-indol-3-yl)thio)-2-fluorobenzoic acid sodium salt


name: Synthesis of 3-((2,6-dichloro-7-fluoro-1-(1-methyl-1H-pyrazol-4-yl)-1H-indol-3-yl)thio)-2-fluorobenzoic acid sodium salt


name: Synthesis of 3-((6-chloro-2-cyclopropyl-7-fluoro-1-(1H-pyrazol-4-yl)-1H-indol-3-yl)thio)-2-fluorobenzoic acid sodium salt


name: Synthesis of 3-((6-chloro-2-cyclopropyl-7-fluoro-1-(1-(2-hydroxyethyl)-1H-pyrazol-4-yl)-1H-indol-3-yl)thio)-2-fluorobenzoic acid sodium salt


name: Synthesis of 34(1-(1-(2-(carbamoyloxy)ethyl)-1H-pyrazol-4-yl)-6-chloro-2-cyclopropyl-7-fluoro-1H-indol-3-yl)thio)-2-fluorobenzoic acid sodium salt


name: Synthesis of 3-((1-(1-(2-aminoethyl)-1H-pyrazol-4-yl)-6-chloro-2-cyclopropyl-7-fluoro-1H-indol-3-yl)thio)-2-fluorobenzoic acid sodium salt


name: Synthesis of 3-((6-chloro-2-cyclopropyl-7-fluoro-1-(1-(2-ureidoethyl)-1H-pyrazol-4-yl)-1H-indol-3-yl)thio)-2-fluorobenzoic acid sodium salt


name: Synthesis of 34(1-(1-(3-carboxypropyl)-1H-pyrazol-4-yl)-6-chloro-2-cyclopropyl-7-fluoro-1H-indol-3-yl)thio)-2-fluorobenzoic acid sodium salt


name: Synthesis of 34(1-(1-(4-amino-4-oxobutyl)-1H-pyrazol-4-yl)-6-chloro-2-cyclopropyl-7-fluoro-1H-indol-3-yl)thio)-2-fluorobenzoic acid sodium salt


name: Synthesis of 3-((1-(1-(6-aminoethyl)-1H-pyrazol-4-yl)-6-chloro-2-cyclopropyl-7-fluoro-1H-indol-3-yl)thio)-2-fluorobenzoic acid sodium salt


name: Synthesis of 3-((6-chloro-2-cyclopropyl-7-fluoro-1-(1-(hex-5-yn-1-yl)-1H-pyrazol-4-yl)-1H-indol-3-yl)thio)-2-fluorobenzoic acid sodium salt


name: Synthesis of 3-((1-(1-(3-hydroxy-2,2-dimethylpropyl)-1H-pyrazol-4-yl)-6-chloro-2-cyclopropyl-7-fluoro-1H-indol-3-yl)thio)-2-fluorobenzoic acid sodium salt


name: Synthesis of 3-(((6-chloro-2-cyclopropyl-1-(1-(6-(3-(3',6'-dihydroxy-3-oxo-3H-spiro[isobenzofuran-1,9'-xanthen]-5-yl)ureido)hexyl)-1H-pyrazol-4-yl)-7-fluoro-1H-indol-3-yl)thio)-2-fluoro benzoic acid sodium salt


name: Synthesis of 34(2,6-dichloro-7-fluoro-1-(pyridin-3-yl)-1H-indol-3-yl)thio)-2-fluorobenzoic acid sodium salt


name: Synthesis of 34(2-bromo-6-chloro-7-fluoro-1-(pyridin-3-yl)-1H-indol-3-yl)thio)-2-fluorobenzoic acid


name: Synthesis of 3-((6-chloro-2-cyclopropyl-7-fluoro-1-(pyridin-3-yl)-1H-indol-3-yl)thio)-2-fluorobenzoic acid sodium salt


sotorasib

A pyridopyrimidine that is pyrido[2,3-d]pyrimidin-2(1H)-one substituted by 4-methyl-2-(propan-2-yl)pyridin-3-yl, (2S)-2-methyl-4-(prop-2-enoyl)piperazin-1-yl, fluoro and 2-fluoro-6-hydroxyphenyl groups at positions 1, 4, 6 and 7, respectively. It is approved for the treatment of patients with non-small cell lung cancer having KRAS(G12C) mutations.


name: Synthesis of (E)-3(4(((2(4cyclopropylphenyl)cyclopropl)amino)methyl)phenyl)-N-hydroxyacrylamide (XLIV)


name: 2-[4-(2-Phenyl-cyclopropylamino)-piperidin-1-yl]-pyrimidine-5-carboxylic Acid Hydroxyamide TFA Salt


name: 2-{4-[2-(4-Fluoro-phenyl)-cyclopropylamino]-piperidin-1-yl}-pyrimidine-5-carboxylic acid hydroxyamide TFA salt


name: 4-(2-Phenyl-cyclopropylamino)-cyclohexanecarboxylic Acid Hydroxyamide TFA Salt


name: N-hydroxy-4-(3-(4-((methyl (2-phenylcyclopropyl)amino) methyl) piperidin-1-yl) propyl) benzamide TFA Salt


name: 4-(3-(3-(((2-(4-fluorophenyl)cyclopropyl)amino)methyl)azetidin-1-yl)propyl)-N-hydroxy benzamide TFA Salt


name: 4-(3-(3-(((2-(4'-fluoro-[1,1'-biphenyl]-4-yl)cyclopropyl)amino)methyl)azetidin-1-yl) propyl)-N-hydroxybenzamide TFA Salt


name: N-hydroxy-4-(3-(4-(((2-(4-(1-methyl-1H-pyrazol-4-yl)phenyl)cyclopropyl)amino)methyl)piperidin-1-yl) propyl) benzamide TFA Salt


name: N-hydroxy-4-(3-(4-(((2-phenylcyclopropyl)amino)methyl)-1H-imidazol-1-yl)propyl) benzamide TFA Salt


name: N-hydroxy-4-(2-oxo-2-(4-((((1R,2S)-2-phenylcyclopropyl)amino)methyl)piperidin-1-yl) ethyl)benzamide TFA Salt


name: N-hydroxy-4-(2-oxo-2-(4-((((1S,2R)-2-phenylcyclopropyl)amino)methyl)piperidin-1-yl) ethyl)benzamide TFA Salt


name: N-(2-aminophenyl)-4-(3-(4-(((2-phenylcyclopropyl)amino)methyl)-1H-imidazol-1-yl) propyl)benzamide TFA Salt


name: N-(2-aminophenyl)-4-(2-((2-(4-fluorophenyl)cyclopropyl)amino)ethoxy) benzamide TFA Salt


name: FYV1_HUMAN 1-phosphatidylinositol 3-phosphate 5-kinase (sprot)

description: A 1-phosphatidylinositol 3-phosphate 5-kinase that is encoded in the genome of human.


name: KCNQ2_HUMAN Potassium voltage-gated channel subfamily KQT member 2 (sprot)

description: A voltage-gated potassium channel subunit KCNQ2 that is encoded in the genome of human.


poziotinib

A member of the class of quinazolines that is quinazoline substituted by (3,4-dichloro-2-fluorophenyl)amino, [1-(prop-2-enoyl)piperidin-4-yl]oxy, and methoxy groups at positions 4, 6, and 7, respectively. It is a potent and irreversible tyrosine kinase inhibitor targeting EGFR and HER2 with exon 20 insertion mutations.


CP4F2_HUMAN Cytochrome P450 4F2 (sprot)

A cytochrome P450 4F2 that is encoded in the genome of human.


name: CP4AB_HUMAN Cytochrome P450 4A11 (sprot)

description: A cytochrome P450 4A11 that is encoded in the genome of human.


name: A0A0D1DYD5_USTMA Acetyl-CoA carboxylase (trembl)


CRBN_MOUSE Protein cereblon (sprot)

A protein cereblon that is encoded in the genome of mouse.


name: HAOX1_HUMAN 2-Hydroxyacid oxidase 1 (sprot)

description: A 2-hydroxyacid oxidase 1 that is encoded in the genome of human.


name: phenyl 5-(4-((4-(1H-pyrazol-4-yl)phenyl) amino)pyrimidin-2-yl) isoindoline-2-caiboxylate


name: 2-azaspiro[3.3]heptan 6-yl 5-(4-((4-(1H-pyrazol-4-yl)phenyl)amino) pyrimidin-2-yl)isoindoline-2-carboxylate


CCNK_HUMAN Cyclin-K (sprot)

A cyclin-K that is encoded in the genome of human.


name: 3-(4-Morpholinyl)-2-pyridinecarboxylic acid ethyl ester


name: 2-Chloro-6-cyclopropyl-3-pyridinecarboxylic acid ethyl ester


name: 2-Cyclopropyl-4-(4-morpholinyl)-5-pyrimidinecarboxylic acid ethyl ester


name: 5-Bromo-2-chloro-6-cyclopropyl-3-pyridinecarboxylic acid methyl ester


name: 5-Chloro-2-(2-pyridinyl)-4-thiazolecarboxylic acid methyl ester


name: 3-(4-Morpholinyl)-2-furancarboxylic acid methyl ester


visnagin

A furanochromone that is furo[3,2-g]chromen-5-one which is substituted at positions 4 and 7 by methoxy and methyl groups, respectively. Found in the toothpick-plant, Ammi visnaga.


name: CP343_HUMAN Cytochrome P450 3A43 (sprot)

description: A cytochrome P450 3A43 that is encoded in the genome of human.


name: PRKN_HUMAN E3 ubiquitin-protein ligase parkin (sprot)

description: An E3 ubiquitin-protein ligase parkin that is encoded in the genome of human.


A cyclic purine dinucleotide that consists of AMP and GMP units cyclised via 3',5'- and 2',5'-linkages respectively.


(-)-menthol

A p-menthan-3-ol which has (1R,2S,5R)-stereochemistry. It is the most common naturally occurring enantiomer.


name: [4-(2-{2-[3-(5-tert-Butyl-2H-pyrazol-3-yl)-ureido]-thiazol-5-yl}-ethyl)-pyridin-2-yl]-carbamic acid ethyl ester


name: [4-(2-{2-[3-(5-tert-Butyl-isoxazol-3-yl)-ureido]-thiazol-5-yl}-ethyl)-pyridin-2-yl]-carbamic acid ethyl ester


name: [4-(2-{2-[3-(5-tert-Butyl-2-methyl-2H-pyrazol-3-yl)-ureido]-thiazol-5-yl}-ethyl)-pyridin-2-yl]-carbamic acid ethyl ester


name: [4-(4-{3-[5-(3-Methyl-thietan-3-yl)-2-p-tolyl-2H-pyrazol-3-yl]-ureido}-phenoxy)-pyridin-2-yl]-carbamic acid methyl ester


name: [4-(4-{3-[5-(3-Methyl-oxetan-3-yl)-2-p-tolyl-2H-pyrazol-3-yl]-ureido}-phenoxy)-pyridin-2-yl]-carbainic acid methyl ester


name: 5-[2-(3-fluoro-phenyl)-[1,2,4]triazolo[1,5-a]pyridin-7-ylcarbamoyl]-1-methyl-1H-pyrazole-4-carboxylic acid ethyl ester


name: 5-[2-(2-methoxy-phenyl)-[1,2,4]triazolo[1,5-a]pyridin-7-ylcarbamoyl]-1-methyl-1H-pyrazole-4-carboxylic acid ethyl ester


name: 1-methyl-5-(2-pyrrolidin-1-yl-[1,2,4]triazolo[1,5-a]pyridin-7-ylcarbamoyl)-1H-pyrazole-4-carboxylic acid ethyl ester


name: 1-methyl-5-(2-morpholin-4-yl-[1,2,4]triazolo[1,5-a]pyridin-6-ylcarbamoyl)-1H-pyrazole-4-carboxylic acid ethyl ester


name: (S)-4-((2-ethoxyethyl) (4-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl) butyl)amino)-2-(quinazolin-4-ylamino) butanoic acid


POL_HV1LW Gag-Pol polyprotein (sprot)

A lentivirus-type gag-pol polyprotein that is encoded in the genome of Human immunodeficiency virus type 1 group M subtype B (isolate LW123).


name: NSD2_HUMAN Histone-lysine N-methyltransferase NSD2 (sprot)

description: A histone-lysine N-methyltransferase NSD2 that is encoded in the genome of human.


name: (R)-(3-aminopiperidin-1-yl) (3-methyl-2-(1-(pyrimidin-5-ylmethyl)-1H-indol-2-yl) imidazo[1,2-a]pyridin-7-yl)methanone Trifluoroacetic Acid Salt


name: Synthesis of (R)-(3-aminopiperidin-1-yl)(2-(1-(2,2-difluoroethyl)-1H-indol-2-yl)-3-methylimidazo[1,2-a]pyridin-7-yl)methanone Trifluoroacetic Acid Salt


name: NSMA2_HUMAN Sphingomyelin phosphodiesterase 3 (sprot)

description: A sphingomyelin phosphodiesterase 3 that is encoded in the genome of human.


name: MRE11_HUMAN Double-strand break repair protein MRE11 (sprot)

description: A double-strand break repair protein MRE11 that is encoded in the genome of human.


name: LATS2_HUMAN Serine/threonine-protein kinase LATS2 (sprot)

description: A serine/threonine-protein kinase LATS2 that is encoded in the genome of human.


name: TEAD1_HUMAN Transcriptional enhancer factor TEF-1 (sprot)

description: A transcriptional enhancer factor TEF-1 that is encoded in the genome of human.


name: TAPT1_HUMAN Transmembrane anterior posterior transformation protein 1 homolog (sprot)

description: A transmembrane anterior posterior transformation protein 1 that is encoded in the genome of human.


name: 1-Piperidinecarboxylic acid, 4-[4-[(2,6-dioxo-3-piperidinyl)amino]phenyl]-, 1,1-dimethylethyl ester


name: CBLB_HUMAN E3 ubiquitin-protein ligase CBL-B (sprot)

description: An E3 ubiquitin-protein ligase CBL-B that is encoded in the genome of human.


name: NMD3B_HUMAN Glutamate receptor ionotropic, NMDA 3B (sprot)

description: A glutamate receptor ionotropic, NMDA 3B that is encoded in the genome of human.


name: HBEAG_HBVGB External core antigen (sprot)

description: A hepadnavirus-type e antigen that is encoded in the genome of Gibbon hepatitis B virus subtype ayw3q (isolate Hope).


A chloropyridine that is 3-chloropyridine substituted by a 1-oxo-2,8-diazaspiro[4.5]decan-8-yl group and a 4-(1-methyl-1H-pyrazol-4-yl)phenyl group at positions 4 and 5, respectively. It is an orally bioavailable inhibitor of Wnt signaling (IC50 = 5 nM) and a potent and selective chemical probe for cyclin-dependent kinases CDK8 and CDK19.


name: AOC2_HUMAN Amine oxidase [copper-containing] 2 (sprot)

description: A retina-specific copper amine oxidase that is encoded in the genome of human.


name: F13B_HUMAN Coagulation factor XIII B chain (sprot)

description: A coagulation factor XIII B chain that is encoded in the genome of human.


name: F13A_MOUSE Coagulation factor XIII A chain (sprot)

description: A coagulation factor XIII A chain that is encoded in the genome of mouse.


name: F13A_RAT Coagulation factor XIII A chain (sprot)

description: A coagulation factor XIII A chain that is encoded in the genome of rat.


name: TGM7_HUMAN Protein-glutamine gamma-glutamyltransferase Z (sprot)

description: A protein-glutamine gamma-glutamyltransferase Z that is encoded in the genome of human.


name: HEM0_HUMAN 5-aminolevulinate synthase, erythroid-specific, mitochondrial (sprot)

description: A 5-aminolevulinate synthase, erythroid-specific, mitochondrial that is encoded in the genome of human.


ACLY_HUMAN ATP-citrate synthase (sprot)

An ATP-citrate synthase that is encoded in the genome of human.


name: KAT6B_HUMAN Histone acetyltransferase KAT6B (sprot)

description: A histone acetyltransferase KAT6B that is encoded in the genome of human.


name: KAT5_HUMAN Histone acetyltransferase KAT5 (sprot)

description: A histone acetyltransferase KAT5 that is encoded in the genome of human.


name: KAT7_HUMAN Histone acetyltransferase KAT7 (sprot)

description: A histone acetyltransferase KAT7 that is encoded in the genome of human.


name: KAT8_HUMAN Histone acetyltransferase KAT8 (sprot)

description: A histone acetyltransferase KAT8 that is encoded in the genome of human.


A monocarboxylic acid amide obtained by formal condensation between the carboxy group of 3,4-dichlorophenylacetic acid and the secondary amino group of (1R,2R)-N-methyl-2-(pyrrolidin-1-yl)cyclohexanamine


name: Q8R492_RAT Fibroblast activation protein, alpha (trembl)


name: PREP_MOUSE Presequence protease, mitochondrial (sprot)

description: A presequence protease, mitochondrial that is encoded in the genome of mouse.


name: PREP_HUMAN Presequence protease, mitochondrial (sprot)

description: A presequence protease, mitochondrial that is encoded in the genome of human.


name: MTDC_HUMAN Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial (sprot)

description: A bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial that is encoded in the genome of human.


CUL2_HUMAN Cullin-2 (sprot)

A cullin-2 that is encoded in the genome of human.


name: MPRD_HUMAN Cation-dependent mannose-6-phosphate receptor (sprot)

description: A cation-dependent mannose-6-phosphate receptor that is encoded in the genome of human.


name: (S)-2-(3,5-dichlorobiphenyl-4-ylcarboxamido)-3-(2-(3 guanidino-N-methylbenzamido) acetamido)propanoic acid


name: General Procedure for Preparation of 3-(4-(5'-(4-fluorophenyl)-3'-isopropyl-1H,3'H-[2,4'-biimidazole]-4-carboxamido)phenyl)propanoic acid


name: General Procedure for Preparation of 5'-(4-fluorophenyl)-N-(4-(4-methylpiperazin-1-yl)phenyl)-3'-(2,2,2-trifluoroethyl)-1H,3'H-[2,4'-biimidazole]-4-carboxamide


name: DRTS_TRYCR Bifunctional dihydrofolate reductase-thymidylate synthase (sprot)


name: DRTS_TRYBB Bifunctional dihydrofolate reductase-thymidylate synthase (sprot)


SALL4_HUMAN Sal-like protein 4 (sprot)

A Sal-like protein 4 that is encoded in the genome of human.


name: KCNJ3_HUMAN G protein-activated inward rectifier potassium channel 1 (sprot)

description: A G protein-activated inward rectifier potassium channel 1 that is encoded in the genome of human.


esomeprazole

A 5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole that has S configuration at the sulfur atom. An inhibitor of gastric acid secretion, it is used (generally as its sodium or magnesium salt) for the treatment of gastro-oesophageal reflux disease, dyspepsia, peptic ulcer disease, and Zollinger-Ellison syndrome.


A member of the class of benzamides obtained by formal condensation of the carboxy group of 3-{3-bromo-4-[(2,4-difluorobenzyl)oxy]-6-methyl-2-oxopyridin-1-yl}-4-methylbenzoic acid with the amino group of methylamine.


name: 4-[5-(2-Amino-pyrimidin-4-yl)-4-(4-fluoro-phenyl)-imidazol-1-yl]-piperidine-1-carboxylic acid ethyl ester


A piperidinylimidazole that is 1H-imidazole carrying a piperidin-4-yl group, 4-fluorophenyl group and a 2-(3,5-dimethylphenoxy)pyrimidin-4-yl group at positions 1, 4 and 5 respectively. It is a potent inhibitor of  p38alpha mitogen-activated protein kinase and BRD4.


A pyrrolopyrimidine that is 7H-pyrrolo[2,3-d]pyrimidine substituted at position 4 by a methyl[(3R,4R)-4-methyl-1-(pyrrolidin-1-ylcarbonyl)piperidin-3-yl]nitrilo group. It is a potent JAK3-selective chemical probe.


name: EZH1_HUMAN Histone-lysine N-methyltransferase EZH1 (sprot)

description: A histone-lysine N-methyltransferase EZH1 that is encoded in the genome of human.


name: GBRG1_RAT Gamma-aminobutyric acid receptor subunit gamma-1 (sprot)

description: A gamma-aminobutyric acid receptor subunit gamma-1 that is encoded in the genome of rat.


fluticasone

A trifluorinated corticosteroid used in the form of its propionate ester for treatment of allergic rhinitis.


SSXT_HUMAN Protein SSXT (sprot)

A protein SSXT that is encoded in the genome of human.


name: (1S,2S)-N-(8-amino-7-fluoro-6-(4-methylpyridin-3-yl)isoquinolin-3-yl)-2-(1-methyl-1H-1,2,3-triazol-4-yl)cyclopropane-l-carboxamide (Relative stereochemistry as drawn; Absolute stereochemistry arbitrarily assigned)


name: (1R,2R)-N-(8-amino-7-fluoro-6-(4-methylpyridin-3-yl)isoquinolin-3-yl)-2-(1-methyl-1H-1,2,3-triazol-4-yl)cyclopropane-l-carboxamide (Relative stereochemistry as drawn; Absolute stereochemistry arbitrarily assigned)


name: MASP2_HUMAN Mannan-binding lectin serine protease 2 (sprot)

description: A mannan-binding lectin serine protease 2 that is encoded in the genome of human.


name: 2-Furancarboxylic acid, 3-nitrophenyl ester


name: DGKA_HUMAN Diacylglycerol kinase alpha (sprot)

description: A diacylglycerol kinase alpha that is encoded in the genome of human.


name: DGKZ_HUMAN Diacylglycerol kinase zeta (sprot)

description: A diacylglycerol kinase zeta that is encoded in the genome of human.


name: ERCC5_HUMAN DNA excision repair protein ERCC-5 (sprot)

description: A DNA excision repair protein ERCC-5 that is encoded in the genome of human.


cisapride

The amide resulting from formal condensation of 4-amino-5-chloro-2-methoxybenzoic acid with cis-1-[3-(4-fluorophenoxy)propyl]-3-methoxypiperidin-4-amine. It has been used (as its monohydrate or as its tartrate) for the treatment of gastro-oesophageal reflux disease and for non-ulcer dyspepsia, but its propensity to cause cardiac arrhythmias resulted in its complete withdrawal from many countries, including the U.K., and restrictions on its use elsewhere.


name: FKBP5_HUMAN Peptidyl-prolyl cis-trans isomerase FKBP5 (sprot)

description: A peptidyl-prolyl cis-trans isomerase FKBP5 that is encoded in the genome of human.


name: LOX15_PIG Polyunsaturated fatty acid lipoxygenase ALOX15 (sprot)


name: KCNJ2_HUMAN Inward rectifier potassium channel 2 (sprot)

description: An inward rectifier potassium channel 2 that is encoded in the genome of human.


A pyrazolopyrimidine that is 1H-pyrazolo[3,4-d]pyrimidin-4-amine which is substituted at positions 1 and 3 by tetrahydro-2H-pyran-4-yl and (m-chlorophenoxy)methyl groups, respectively. It is a selective inhibitor of the epsilon isoform of casein kinase 1 (CK1epsilon).


name: 2-cyano-2-[3-(4-ethyl-1-piperazinyl)-2-quinoxalinyl]acetic acid cyclohexyl ester


name: NOTUM_HUMAN Palmitoleoyl-protein carboxylesterase NOTUM (sprot)

description: A protein notum that is encoded in the genome of human.


AMPYRONE

A pyrazolone, a member of the class of  pyrazoles that is antipyrine substituted at C-4 by an amino group.  It is a metabolite of aminopyrine and of metamizole.


name: Synthesis of (E)-5-((2-(aminomethyl)-3-fluoroallyl)oxy)-2-cyclopropyl isoindolin-1-one


name: Synthesis of (E)-5-((2-(aminomethyl)-3-fluoroallyl)oxy)-2-cyclopropyl isoindolin-1,3-dione


enoxolone

A pentacyclic triterpenoid that is olean-12-ene substituted by a hydroxy group at position 3, an oxo group at position 11 and a carboxy group at position 30.


ARJUNOLIC ACID

A  pentacyclic triterpenoid that is  olean-12-en-28-oic acid substituted by hydroxy groups at positions 2, 3 and 23 (the 2alpha,3beta stereoisomer). Isolated from Symplocos lancifolia and Juglans sinensis, it exhibits antioxidant and antimicrobial activities.


HEDERAGENIN

A sapogenin that is olean-12-en-28-oic acid substituted by hydroxy groups at positions 3 and 23 (the 3beta stereoisomer).


LUPEOL

A pentacyclic triterpenoid that is lupane in which the hydrogen at the 3beta position is substituted by a hydroxy group. It occurs in the skin of lupin seeds, as well as in the latex of fig trees and of rubber plants. It is also found in many edible fruits and vegetables.


alpha-amyrin

A pentacyclic triterpenoid that is ursane which contains a double bond between positions 12 and 13 and in which the hydrogen at the 3beta position is substituted by a hydroxy group.


BEVIRIMAT

A pentacyclic triterpenoid obtained by the formal condensation of 2,2-dimethylsuccinic acid with the 3-hydroxy group of betulinic acid. It is isolated from the Chinese herb Syzygium claviflorum. The first in the class of HIV-1 maturation inhibitors to be studied in humans, bevirimat was identified as a potent HIV drug candidate and several clinical trials were conducted, but development into a new drug was plagued by numerous resistance-related problems.


name: 6,7-dimethoxy-N-[1-(propan-2-yl)piperidin-4-yl]-1,2,3,4-tetrahydroacridin-9-amine; bis (formic acid)


name: N-[2,3-dimethoxy-6H,7H,8H-cyclopenta[b]1,5-naphthyridin-9-yl]-1-(propan-2-yl)piperidin-4-amine (bis formic acid salt)


name: (3R)â??N-[2, 3-dimethoxy-6H, 7H, 8Hcyclopenta [b]1,5 naphthyridin-9-yl] piperidin-3-amineâ??HCl


name: (3R)â??N-[2, 3-dimethoxy-6H, 7H, 8H-cyclopenta[b] 1, 5-naphthyridin-9-yl]-1-methylpiperidin-3-amineâ??HCl


name: (3R)â??N-[2, 3-dimethoxy-6H, 7H, 8H-cyclopenta[b] 1, 5-naphthyridin-9-yl] azepan-3-amineâ??HCl


name: (4R)â??N-[2, 3-dimethoxy-6H, 7H, 8H-cyclopenta[b] 1, 5-naphthyridin-9-yl] azepan-4-amineâ??HCl


name: (3R)â??N-[2, 3-dimethoxy-6H, 7H, 8H-cyclopenta[b]1, 5-naphthyridin-9-yl]-1-methylazepan-3-amine-HCl


name: Preparation of (2R,4S)N((S)-1-((4-((Z)N'-((L-valyl)oxy)carbamimidoyl)benzyl)amino)-1-oxopropan-2-yl)-4-phenylpiperidine-2-carboxamide dihydrochloride salt


name: Preparation of (2R,4S)-2-(((S)-1-((4-carbamimidoylbenzyl)amino)-1-oxopropan-2-yl)carbamoyl)-1,1-dimethyl-4-phenylpiperidin-1-ium 2,2,2-trifluoroacetate trifluoroacetic Acid salt


name: Preparation of 3-((2R,4S)-2-(((S)-1-((4-carbamimidoylbenzyl)amino)-1-oxopropan-2-yl)carbamoyl)-4-phenylpiperidin-1-yl)propanoic acid di-trifluoroacetate salt


name: Preparation of (S)N-(4-carbamimidoylbenzyl)-1-((2R,4S)-1-methyl-4-phenylpiperidine-2-carbonyl)azetidine-2-carboxamide di-trifluoroacetate SALT


name: Preparation of benzyl (imino(4-(((S)-1-((2R,4S)-4-phenylpiperidine-2-carbonyl)azetidine-2-carboxamido)methyl)phenyl)methyl)carbamate di-trifluoroacetate salt


name: S47A2_HUMAN Multidrug and toxin extrusion protein 2 (sprot)

description: A multidrug and toxin extrusion protein 2 that is encoded in the genome of human.


GRAB_HUMAN Granzyme B (sprot)

A granzyme B that is encoded in the genome of human.


pexidartinib

A pyrrolopyridine that is 5-chloro-1H-pyrrolo[2,3-b]pyridine which is substituted by a [6-({[6-(trifluoromethyl)pyridin-3-yl]methyl}amino)pyridin-3-yl]methyl group at position 3. It is a potent multi-targeted receptor tyrosine kinase inhibitor of CSF-1R, KIT, and FLT3 (IC50 of 20 nM, 10 nM and 160 nM, respectively). Approved by the FDA for the treatment of adult patients with symptomatic tenosynovial giant cell tumor (TGCT).


name: HSF1_HUMAN Heat shock factor protein 1 (sprot)

description: A heat shock factor protein 1 that is encoded in the genome of human.


A bismuth cation having a net electric charge of +3.


name: S13A5_HUMAN Na(+)/citrate cotransporter (sprot)

description: A Na(+)/citrate cotransporter that is encoded in the genome of human.


APEL_HUMAN Apelin (sprot)

An apelin that is encoded in the genome of human.


name: HEMA_I86A0 Hemagglutinin (Fragment) (sprot)


HPSE_HUMAN Heparanase (sprot)

A heparanase that is encoded in the genome of human.


name: SDHB_HUMAN Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial (sprot)

description: A succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial that is encoded in the genome of human.


name: MET14_HUMAN N6-adenosine-methyltransferase non-catalytic subunit (sprot)

description: An N6-adenosine-methyltransferase non-catalytic subunit that is encoded in the genome of human.


name: BLVRB_HUMAN Flavin reductase (NADPH) (sprot)

description: A flavin reductase that is encoded in the genome of human.


olsalazine

An azobenzene that consists of two molecules of 4-aminosalicylic acid joined by an azo linkage. A prodrug for mesalazine, an anti-inflammatory drug, it is used (as the disodium salt) in the treatment of inflammatory bowel disease.


flunixin

A pyridinemonocarboxylic acid that is nicotinic acid substituted at position 2 by a 2-methyl-3-(trifluoromethyl)phenylamino group. A relatively potent non-narcotic, nonsteroidal analgesic with anti-inflammatory, anti-endotoxic and anti-pyretic properties; used in veterinary medicine (usually as the meglumine salt) for treatment of horses, cattle and pigs.


APOL1_HUMAN Apolipoprotein L1 (sprot)

An apolipoprotein L1 that is encoded in the genome of human.


name: ACSA_HUMAN Acetyl-coenzyme A synthetase, cytoplasmic (sprot)

description: An acetyl-coenzyme A synthetase, cytoplasmic that is encoded in the genome of human.


name: SARM1_HUMAN NAD(+) hydrolase SARM1 (sprot)

description: An NAD(+) hydrolase SARM1 that is encoded in the genome of human.


name: Thioperoxydicarbonic diamide ([(H2N)C(S)]2S2), N,N inverted exclamation marka-diethyl-N,N inverted exclamation marka-bis(2-hydroxyethyl)-


TGF-beta RI inhibitor III

A member of the class of imidazoles carrying tert-butyl, 1,3-benzodioxol-5-yl and 6-methylpyridin-2-yl substituents at positions 2, 4 and 5 respectively.


LIMK2_HUMAN LIM domain kinase 2 (sprot)

A LIM domain kinase 2 that is encoded in the genome of human.


name: GPR52_HUMAN G-protein coupled receptor 52 (sprot)

description: A G-protein coupled receptor 52 that is encoded in the genome of human.


name: ALKB5_HUMAN RNA demethylase ALKBH5 (sprot)

description: An alkylated DNA repair protein alkB 5 that is encoded in the genome of human.


name: YTHD2_HUMAN YTH domain-containing family protein 2 (sprot)

description: A YTH domain-containing family protein 2 that is encoded in the genome of human.


name: YTHD1_HUMAN YTH domain-containing family protein 1 (sprot)

description: A YTH domain-containing family protein 1 that is encoded in the genome of human.


6-aminopenicillanic acid

A penicillanic acid compound having a (6R)-amino substituent. The active nucleus common to all penicillins, it may be substituted at the 6-amino position to form the semisynthetic penicillins, resulting in a variety of antibacterial and pharmacologic characteristics.


A member of the class of benzimidazoles that is 1H-benzimidazole substituted by a 2-aminophenyl group at position 2.


L-tyrosinamide

An amino acid amide that is L-tyrosine in which the carboxy OH group is replaced by NH2.


An aminobiphenyl that is biphenyl substituted by an amino group at position 4.


octopamine

A member of the class of phenylethanolamines that is phenol which is substituted at the para- position by a 2-amino-1-hydroxyethyl group. A biogenic phenylethanolamine which has been found to act as a neurotransmitter, neurohormone or neuromodulator in invertebrates.


A multi-substituted pyrazolecarboxamide used in the industrial synthesis of sildenafil.


A dichloroaniline having the two chloro-substituents at the 3- and 4-positions.


An acetamide that is 1,4-phenylenediamine in which the the amino group at position 4 is replaced by an acetylamino group.


heliamine

An isoquinoline that is 1,2,3,4-tetrahydroisoquinoline substituted by methoxy groups at positions 6 and 7.


A  substituted aniline that is a benzene ring substituted with an amino group at position 1 and a trifluoromethyl group at position 4.


A substituted aniline that is 3-nitroanisole in which the hydrogen para to the methoxy group is replaced by an amino group.


glucosamine

A D-glucosamine whose structure comprises D-glucopyranose having an amino substituent at position 2.


DOXECITINE

A pyrimidine 2'-deoxyribonucleoside having cytosine as the nucleobase.


PYRIDOXAMINE

A monohydroxypyridine that is pyridine substituted by a hydroxy group at position 3, an aminomethyl group at position 4, a hydroxymethyl group at position 5 and a methyl group at position 2. The 4-aminomethyl form of vitamin B6, it is used (in the form of the hydrochloride salt) for treatment of diabetic nephropathy.


(R)-methylmalonyl-CoA

The (R)-enantiomer of methylmalonyl-CoA.


succinyl-CoA

An omega-carboxyacyl-CoA having succinoyl as the S-acyl component.


hexanoyl-CoA

A medium-chain fatty acyl-CoA having hexanoyl as the S-acyl group.


daclatasvir

A member of the class of biphenyls that is a potent inhibitor of nonstructural protein 5A and is used (as its hydrochloride salt) for treatment of hepatitis C.


alanyl glutamine

A dipeptide formed from L-alanyl and L-glutamine residues.


rhuscholide A

A member of the class of 1-benzofurans that is 1-benzofuran-2(3H)-one substituted by a hydroxy group at position 5, a propan-2-ylidene group at position 3 and a (2E,6E,10E)-3,7,11,15-tetramethylhexadeca-2,6,10,14-tetraen-1-yl group at position 7. Isolated from Rhus chinensis, it exhibits anti-HIV activity.


XANTHOHUMOL

A member of the class of chalcones that is trans-chalcone substituted by hydroxy groups at positions 4, 2' and 4', a methoxy group at position 6' and a prenyl group at position 3'. Isolated from Humulus lupulus, it induces apoptosis in human malignant glioblastoma cells.


A heteroarenecarbaldehyde that is indole in which the hydrogen at position 4 has been replaced by a formyl group.


name: ((((2,2'-Dimethyl-[1,1'-biphenyl)-3,3'-diyl) bis (methylene)) bis (oxo)) bis (2-methoxypyridine-6,3-diyl)) dimethylamine


name: 1,1'-(((((2,2'-Dimethyl-[1,1'-biphenyl]-3,3'-diyl) bis (methylene)) bis (oxo))bis (2-methoxypyridine-6,3-diyl)) bis (methylene)) bis (piperidine-2-carboxylic acid)


name: (3'-(((5-(2-Aminoethyl)-6-methoxypyridin-2-yl) oxo) methyl)-2,2'-dimethyl-[1,1'-biphenyl]-3-yl) methanol


name: N, N'-((((((((2-methyl-1,3-phenylene) bis (methylene)) bis (oxo)) bis (2-methoxypyridine-6,3-diyl)) bis (methylene)) bis (azetanediyl)) bis (ethane-2,1-diyl)) diacetamide


name: 1,1'-(((((((2,2'-Dimethyl-[1,1'-biphenyl]-3,3'-diyl) bis (methylene)) bis (oxo)) bis (2-methoxypyridine-6,3-diyl)) bis (methylene)) bis (azetanediyl)) bis (2-methylpropane-2-ol)


name: 3,3'-(((((((2,2'-Dimethyl[1,1'-biphenyl]-3,3'-diyl) bis (methylene)) bis (oxo)) bis (2-methoxypyridine-6,3-diyl)) bis (methylene)) bis (azetanediyl)) dipropionamide


name: TEAD2_HUMAN Transcriptional enhancer factor TEF-4 (sprot)

description: A transcriptional enhancer factor TEF-4 that is encoded in the genome of human.


name: TEAD3_HUMAN Transcriptional enhancer factor TEF-5 (sprot)

description: A transcriptional enhancer factor TEF-5 that is encoded in the genome of human.


name: TEAD4_HUMAN Transcriptional enhancer factor TEF-3 (sprot)

description: A transcriptional enhancer factor TEF-3 that is encoded in the genome of human.


name: LOXL3_HUMAN Lysyl oxidase homolog 3 (sprot)

description: A lysyl oxidase homolog 3 that is encoded in the genome of human.


tannic acid

A gallotannin obtained by acylation of the five hydroxy groups of D-glucose by 3,4-dihydroxy-5-[(3,4,5-trihydroxybenzoyl)oxy]benzoic acid (a gallic acid dimer).


name: LYAG_HUMAN Lysosomal alpha-glucosidase (sprot)

description: A lysosomal alpha-glucosidase that is encoded in the genome of human.


name: SRBP2_HUMAN Sterol regulatory element-binding protein 2 (sprot)

description: A sterol regulatory element-binding protein 2 that is encoded in the genome of human.


SYL_ECOLI Leucine--tRNA ligase (sprot)

A leucine--tRNA ligase that is encoded in the genome of Escherichia coli K-12.


name: PMGE_HUMAN Bisphosphoglycerate mutase (sprot)

description: A bisphosphoglycerate mutase that is encoded in the genome of human.


name: SIK3_HUMAN Serine/threonine-protein kinase SIK3 (sprot)

description: A serine/threonine-protein kinase QSK that is encoded in the genome of human.


name: MYT1_HUMAN Myelin transcription factor 1 (sprot)

description: A myelin transcription factor 1 that is encoded in the genome of human.


name: LOXL4_HUMAN Lysyl oxidase homolog 4 (sprot)

description: A lysyl oxidase homolog 4 that is encoded in the genome of human.


name: LYOX_BOVIN Protein-lysine 6-oxidase (sprot)


TLR4_HUMAN Toll-like receptor 4 (sprot)

A Toll-like receptor 4 that is encoded in the genome of human.


name: Preparation of 2-[(R)-3-(8-phenyl)octanoyloxytetradecanoylamino]ethyl 2,3-di-[(R)-3-(8-phenyl)octanoyloxytetradecanoylamino]-2,3-dideoxy-4-O-phosphono-beta-D-allopyranoside triethylammonium Salt


name: CCL4_HUMAN C-C motif chemokine 4 (sprot)

description: A C-C motif chemokine 4 that is encoded in the genome of human.


SBMC_ECOLI DNA gyrase inhibitor (sprot)

A DNA gyrase inhibitor that is encoded in the genome of Escherichia coli K-12.


ATHRAQUINONES A

A dihydroxyanthraquinone that is anthracene-9,10-dione in which the two hydroxy groups are located at positions 1 and 2.


name: DLK1_HUMAN Protein delta homolog 1 (sprot)

description: A protein delta homolog 1 that is encoded in the genome of human.


name: M3K13_HUMAN Mitogen-activated protein kinase kinase kinase 13 (sprot)

description: A mitogen-activated protein kinase kinase kinase 13 that is encoded in the genome of human.


name: ICMT_HUMAN Protein-S-isoprenylcysteine O-methyltransferase (sprot)

description: A protein-S-isoprenylcysteine O-methyltransferase that is encoded in the genome of human.


name: PEX5R_HUMAN PEX5-related protein (sprot)

description: A PEX5-related protein that is encoded in the genome of human.


name: (R and S)-N-(4,4-difluoro-3-piperidyl)-7-[2-(2,2,2-trifluoroethoxy)phenyl] benzofuran-2-carboxamide


name: Cis or trans-5-fluoro-N-(4-hydroxy-1-methyl-cyclohexyl)-7-[2-(2,2,2-trifluoroethoxy)phenyl] benzofuran-2-carboxamide


name: Synthesis of (3S)-3-{[3-cyclopropyl-N-(5,7-difluoro-1H-indole-2-carbonyl)-L-alanyl]amino}-2-oxo-4-[(3S)-2-oxopiperidin-3-yl]butyl L-valinate hydrochloride Salt, 17


SYK_HUMAN Lysine--tRNA ligase (sprot)

A eukaryotic-type lysine--tRNA ligase that is encoded in the genome of human.


cilnidipine

A diesterified 1,4-dihydropyridine-3,5-dicarboxylic acid. A calcium channel blocker, it is used as an antihypertensive.


nisoldipine

A racemate consisting of equimolar amounts of (R)- and (S)-nisoldipine. A calcium channel blocker, it is used in the treatment of hypertension and angina pectoris.


azelastine

A phthalazine compound having an oxo substituent at the 1-position, a 1-methylazepan-4-yl group at the 2-position and a 4-chlorobenzyl substituent at the 4-position.


name: DHB13_HUMAN 17-beta-hydroxysteroid dehydrogenase 13 (sprot)

description: A 17-beta-hydroxysteroid dehydrogenase 13 that is encoded in the genome of human.


name: A0A0K2E2J2_9CALI Genome polyprotein (trembl)


name: NR1D1_HUMAN Nuclear receptor subfamily 1 group D member 1 (sprot)

description: A nuclear receptor subfamily 1 group D member 1 that is encoded in the genome of human.


name: NR1D2_HUMAN Nuclear receptor subfamily 1 group D member 2 (sprot)

description: A nuclear receptor subfamily 1 group D member 2 that is encoded in the genome of human.


name: BRPA_STRMU Biofilm regulatory protein A (sprot)


A hydroxyaurone that is aurone which is substituted by hydroxy groups at the 3' and 4' positions; major species at pH 7.3. It shows inhibitory activity against several isoforms of the histone deacetylase complex (HDAC).


okanin

A member of the class of  chalcones that is  trans-chalcone substituted by hydroxy groups at positions 3, 4, 2', 3', and 4' respectively.


DELPHINIDIN

An anthocyanidin cation consisting of benzopyrylium with hydroxy substituents at the 3-, 5- and 7-positions and a 3,4,5-trihydroxyphenyl group at the 2-position. It is a plant pigment responsible for the colours of the plants of the genera Viola and Delphinium.


ROBINETIN

A pentahydroxyflavone that is flavone substituted by hydroxy groups at positions 3, 7, 3, 4' and 5'.


PETUNIDIN

An anthocyanidin cation that is flavylium bearing five hydroxy substituents at positions 3, 3', 4', 5 and 7 as well as a methoxy substituent at position 5'.


RHAPONTIN

A rhaponticin in which the double bond adopts a trans-configuration. It possesses a range of pharmacological activities including antitumour, antiinflammatory, antilipemic and neuroprotective activities.


name: MASP1_HUMAN Mannan-binding lectin serine protease 1 (sprot)

description: A mannan-binding lectin serine protease 1 that is encoded in the genome of human.


name: Trans-4-((4-((2-(1-(phenylsulfonyl)) indolin-5-yl)cyclopropylamino) methyl)piperidin-1-yl)methyl) benzoic acid


A tetrahydroxyflavone that is kaempferol substituted by a lavandulyl group at position 8. Isolated from Sophora flavescens, it exhibits antioxidant activity.


name: Step 1: Benzyl 3-cyclopropyl-4-hydroxypyrrolidine-1-carboxylate


name: Step 1: ethyl N-benzyl-N-propionylglycinate


name: Step 1: tert-butyl 3-(benzyloxy)-4-hydroxypyrrolidine-1-carboxylate


name: WRN_HUMAN Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN (sprot)

description: A bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN that is encoded in the genome of human.


name: GPR17_HUMAN Uracil nucleotide/cysteinyl leukotriene receptor (sprot)

description: A uracil nucleotide/cysteinyl leukotriene receptor that is encoded in the genome of human.


name: 3-[5-(S or R)-(3,5-difluorophenyl)-6-(S or R)-methyl-3-oxo-6,7-dihydro-3H-pyrrolo[2,1-c][1,2,4]triazol-2(5H)-yl]bicyclo[1.1.1]pentane-1-carbonitrile


POLG_DEN27 Genome polyprotein (sprot)

A dengue virus genome polyprotein that is encoded in the genome of Dengue virus 2 16681-PDK53.


name: Methyl 3-((1-(4-fluoro-3-(trifluoromethyl) phenyl) cyclopropyl)(methoxycarbonyl)amino)azetidine-1-carboxylate


A nucleoside analogue that is cytidine which carries a hydroxy group at the N(4)-positon. It has broad-spectrum antiviral activity against influenza, SARS-CoV , SARS-CoV-2 and MERS-CoV.


A secondary carboxamide resulting from the formal condensation of the carboxy group of 4-isopropoxybenzoic acid with the primary amino group of 2-methylquinolin-8-amine. An allosteric activator of sarco/endoplasmic reticulum Ca(2+)-ATPase (SERCA).


name: PANK3_HUMAN Pantothenate kinase 3 (sprot)

description: A pantothenate kinase 3 that is encoded in the genome of human.


name: 2-[1H-indol-3-yl(oxo)methyl]-4-thiazolecarboxylic acid methyl ester


TLR6_HUMAN Toll-like receptor 6 (sprot)

A Toll-like receptor 6 that is encoded in the genome of human.


name: DGKD_HUMAN Diacylglycerol kinase delta (sprot)

description: A diacylglycerol kinase delta that is encoded in the genome of human.


name: Substituted Phenyl-Isoxazolidin of Comparator Example C


HMOX1_HUMAN Heme oxygenase 1 (sprot)

A heme oxygenase 1 that is encoded in the genome of human.


name: Synthetic Processes to Prepare Intermediates


name: PYRD_MOUSE Dihydroorotate dehydrogenase (quinone), mitochondrial (sprot)

description: A dihydroorotate dehydrogenase (quinone), mitochondrial that is encoded in the genome of mouse.


name: 4-[3-[[(2,5-dichloroanilino)-methyliminomethyl]thio]-2,5-dioxo-1-pyrrolidinyl]benzoic acid methyl ester


name: TF65_MOUSE Transcription factor p65 (sprot)

description: A transcription factor p65 that is encoded in the genome of mouse.


name: BCL9_HUMAN B-cell CLL/lymphoma 9 protein (sprot)

description: A B-cell CLL/lymphoma 9 protein that is encoded in the genome of human.


name: (S)-1-(5H-dibenzo [b,f]azepine-5-carbonyl)-4-(2,2-diphenylacetyl) piperazine-2-carboxylic acid


name: (S)-4-(5H-dibenzo [b,f]azepine-5-carbonyl)-1-(2,2-diphenylacetyl) piperazine-2-carboxylic acid


name: (R)-4-(5H-dibenzo[b,f] azepine-5-carbonyl)-1-(diphenylcarbamoyl) piperazine-2-carboxylic acid


name: (R)-1-(5H-dibenzo [b,f]azepine-5-carbonyl)-4-(diphenylcarbamoyl) piperazine-2-carboxylic acid


name: (S)-4-(diphenylcarbamoyl)-1-(10-methoxy-5H-dibenzo[b,f] azepine-5-carbonyl) piperazine-2-carboxylic acid


name: (S)-4-(bis(2-methoxylphenyl) carbamoyl)-1-(5H-dibenzo [b,f]azepine-5-carbonyl)piperazine-2-carboxylic acid


name: (S)-1-(5H-dibenz o[b,f]azepine-5-c arbonyl)-4-(phen yl(orthomethylph enyl)carbamoyl) piperazine-2-carb oxylic acid


name: (S)-4-(benzyl(ethyl) carbamoyl)-1-(10-oxo-10,11-dihydro-5H-dibenzo [b,f]azepine-5-carbonyl) piperazine-2-carboxylic acid


name: (S)-4-(ethyl (thiophene-3-ylmethyl) carbamoyl)-1-(10-oxo-10,l l-dihydro-5H-dibenzo[b,f] azepine-5-carbonyl) piperazine-2-carboxylic acid


name: (S)-4-(benzyl(methyl) carbamoyl)-1-(1-phenylcyclohexanecarbonyl) piperazine-2-carboxylic acid


name: (S)-4-(benzyl(methyl) carbamoyl)-1-(5H-dibenzo[b,f] azepine-5-carbonyl) piperazine-2-carboxylic acid


name: (S)-1-(5H-dibenzo [b,f]azepine-5-carbonyl)-4-(2-ethyl-2-phenylbutyryl) piperazine-2-carboxylic acid


name: (S)-4-(dibenzylcarbamoyl)-1-(10-oxo-10,11-dihydro-5H-dibenzo[b,f] azepine-5-carbonyl) piperazine-2-carboxylic acid


name: (S)-4-(benzyl (phenyl)carbamoyl)-1-(10-oxo-10,11-dihydro-5H-dibenzo [b,f]azepine-5-carbonyl)piperazine-2-carboxylic acid


name: (S)-4-(2,2-diphenylpropionyl)-1-(10-oxo-10,11-dihydro-5H-dibenzo [b,f]azepine-5-carbonyl) piperazine-2-carboxylic acid


name: (S)-1-(diphenylcarbamoyl)-4-(10-oxo-10,l l-dihydro-5H-dibenzo[b,f]azepine-5-carbonyl) piperazine-2-carboxylic acid


name: (S)-1-(5H-dibenzo[b,f] azepine-5-carbonyl)-4-((2-methoxylphenyl) (phenyl)carbamoyl) piperazine-2-carboxylic acid


name: (S)-4-((2-methoxylphenyl) (phenyl)carbamoyl)-1-(10-oxo-10,l l-dihydro-5H-dibenzo [b,f]azepine-5-carbonyl)piperazine-2-carboxylic acid


name: (S)-4-(benzyl(methyl) carbamoyl)-1-(2,2-diphenylpropionyl) piperazine-2-carboxylic acid


name: (S)-4-(benzo[b]thiophene-3-ylmethyl)(methyl) carbamoyl)-1-(diphenylcarbamoyl) piperazine-2-carboxylic acid


name: (S)-4-(((4,5-dimethylthiophen-2-yl) methyl)(methyl)carbamoyl)-1-(diphenylcarbamoyl) piperazine-2-carboxylic acid


name: (S)-4-(cyclopropyl((5-methylthiophen-2-yl) methyl)carbamoyl)-1-(diphenylcarbamoyl) piperazine-2-carboxylic acid


name: (S)-4-(cyclopropyl((5-methylthiophen-3-yl)methyl) carbamoyl)-1-(diphenylcarbamoyl) piperazine-2-carboxylic acid


name: (S)-1-(diphenylcarbamoyl)-4-(((5-methylthiophen-2-yl) methyl)(phenyl)carbamoyl) piperazine-2-carboxylic acid


name: (S)-4-(((5-chlorothiophene-3-yl)methyl)(ethyl) carbamoyl)-1-(diphenylcarbamoyl) piperazine-2-carboxylic acid


name: GPR52_MOUSE G-protein coupled receptor 52 (sprot)

description: A G-protein coupled receptor 52 that is encoded in the genome of mouse.


name: Preparation of [(1R)-1-(2-chloro-3-pyridyl)ethyl] N-[5-(5-acetamido-6-fluoro-2-pyridyl)-3-methyl-triazol-4-yl]carbamate


name: Preparation of (R)-1-(2-chloropyridin-3-yl)ethyl (4-(4-acetamidophenyl)-1-methyl-1H-1,2,3-triazol-5-yl)carbamate


name: Preparation of (R)-1-(2-chloropyridin-3-4)ethyl (4-(5-formamidopyridin-2-yl)-1-methyl-1H-1,2,3-triazol-5-yl)carbamate


name: Preparation of (S)-2-fluoro-1-phenylethyl (4-(4-((methoxycarbonyl)amino)phenyl)-1-methyl-1H-1,2,3-triazol-5-yl)carbamate


name: Preparation of (R)-1-(2-chloropyridin-3-yl)ethyl (4-(5-acetamidopyridin-2-yl)-1-methyl-1H-1,2,3-triazol-5-yl)carbamate


name: Preparation of (R)-1-(2-chloropyridin-3-yl) ethyl (4-(5-((1r,3R)-3-cyano-3-fluorocyclobutane-1-carboxamido) pyridin-2-yl)-1-methyl-1H-1,2,3-triazol-5-yl)carbamate


name: NR2E1_HUMAN Nuclear receptor subfamily 2 group E member 1 (sprot)

description: A nuclear receptor subfamily 2 group E member 1 that is encoded in the genome of human.


KHK_MOUSE Ketohexokinase (sprot)

A ketohexokinase that is encoded in the genome of mouse.