EDIFENPHOS

An organic thiophosphate that is the O-ethyl-S,S-diphenyl ester of phosphorodithioic acid.  Used to control a variety of fungal diseases on rice including blast, ear blight and stem rot. Edifenphos is moderately toxic to mammals and fish but poses more of a risk to aquatic invertebrates.


A macrolide antibiotic that is erythromycin A in which the ketone group has been converted into the corresponding imine and then reduced to give the corresponding amino compound (the 9S diastereoisomer).


mepivacaine

A piperidinecarboxamide in which N-methylpipecolic acid and 2,6-dimethylaniline have combined to form the amide bond. It is used as a local amide-type anaesthetic.


A nitrile that is pentanenitrile substituted by a 3,4-dimethoxyphenyl group at position 2, a methylamino group at position 4 and an isopropyl group at position 2. It is a metabolite of the drug verapamil.


CP3A6_RABIT Cytochrome P450 3A6 (sprot)

A protein that is a translation product of the CYP3A6 gene in rabbit.


name: NCS1_HUMAN Neuronal calcium sensor 1 (sprot)

description: A neuronal calcium sensor 1 that is encoded in the genome of human.


carbidopa

3-(3,4-Dihydroxyphenyl)propanoic acid in which the hydrogens alpha- to the carboxyl group are substituted by hydrazinyl and methyl groups (S-configuration). Carbidopa is a dopa decarboxylase inhibitor, so prevents conversion of levodopa to dopamine. It has no antiparkinson activity by itself, but is used (commonly as its hydrate) in the management of Parkinson's disease to reduce peripheral adverse effects of levodopa.


name: HCN1_HUMAN Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (sprot)

description: A potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 that is encoded in the genome of human.


name: HCN3_HUMAN Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 (sprot)

description: A potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 that is encoded in the genome of human.


name: HCN2_HUMAN Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (sprot)

description: A potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 that is encoded in the genome of human.


name: rac-2-((3R,5S)-1-(Aminomethyl)-3,5-dimethylcyclohexyl)acetic acid hydrochloride, AldrichCPR


A 1-(phenanthren-2-ylcarbonyl)piperazine-2,3-dicarboxylic acid that has 2S,3R-configuration.


nicotinyl methylamide

A pyridinecarboxamide that is nicotinamide in which one of the amide hydrogens is substituted by a methyl group.


TETRAPROPYLAMMONIUM

A quarternary ammonium cation with four propyl substituents around the central nitrogen.


name: S22AG_HUMAN Solute carrier family 22 member 16 (sprot)

description: A solute carrier family 22 member 16 that is encoded in the genome of human.


chenodeoxycholate

Conjugate base of chenodeoxycholic acid; major species at pH 7.3.


unithiol

An alkanesulfonic acid that is propane-1-sulfonic acid substituted by sulfanyl groups at positions 2 and 3.


phenacetin

A member of the class of acetamides that is acetamide in which one of the hydrogens attached to the nitrogen is substituted by a 4-ethoxyphenyl group.


N-retinylidene-N-retinylethanolamine

A pyridinium ion obtained by formal condensation between two molecules of retinol and one the amino group of ethanolamine. A major constituent of retinal pigment epithelium lipofuscin


D-lactic acid

An optically active form of lactic acid having (R)-configuration.


FRUCTOSE 1,6-DIPHOSPHATE

A D-fructofuranose 1,6-bisphosphate with an alpha-configuration at the anomeric position.


beta-D-glucose 6-phosphate

A D-glucopyranose 6-phosphate in which the anomeric centre has beta-configuration.


LOVASTATIN ACID

A polyketide obtained by hydrolysis of the pyranone ring of lovastatin.


name: MOT10_RAT Monocarboxylate transporter 10 (sprot)

description: A monocarboxylate transporter 10 that is encoded in the genome of rat.


sulfoglycolithocholic acid

The 3-O-sulfo derivative of glycolithocholic acid.


A steroid glucosiduronic acid that consists of 17beta-estradiol having a beta-glucuronyl residue attached at position 17 via a glycosidic linkage.


octanoate

A straight-chain saturated fatty acid anion that is the conjugate base of octanoic acid (caprylic acid); believed to block adipogenesis.


TPP+

A polyatomic cation consisting of four phenyl groups attached to a central phosphonium.


name: S22A1_MOUSE Solute carrier family 22 member 1 (sprot)

description: A solute carrier family 22 member 1 that is encoded in the genome of mouse.


name: S22A2_MOUSE Solute carrier family 22 member 2 (sprot)

description: A solute carrier family 22 member 2 that is encoded in the genome of mouse.


PROSTAGLANDIN D2

A member of the class of  prostaglandins D that is prosta-5,13-dien-1-oic acid substituted by hydroxy groups at positions 9 and 15 and an oxo group at position 11 (the 5Z,9alpha,13E,15S- stereoisomer).


name: SO2A1_MOUSE Solute carrier organic anion transporter family member 2A1 (sprot)

description: A solute carrier organic anion transporter family member 2A1 that is encoded in the genome of mouse.


p-hydroxyhippuric acid

An N-acylglycine that is the 4-hydroxy derivative of hippuric acid.


acetylsalicylate

A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.


17beta-estradiol 3-sulfate

A steroid sulfate obtained by the formal condensation of sulfuric acid with the 3-hydroxy group of 17beta-estradiol.


17beta-estradiol 3-glucosiduronic acid

A steroid glucosiduronic acid that consists of 17beta-estradiol having a beta-glucuronyl residue attached at position 3 via a glycosidic linkage.


testosterone 17-glucosiduronic acid

A steroid glucosiduronic that is testosterone carrying a glucosiduronic acid residue at position 17.


androsterone sulfate

A steroid sulfate that is the 3-sulfate of androsterone.


glycocholate

A cholanic acid conjugate anion that is the conjugate base of glycocholic acid, obtained by deprotonation of the carboxy group; major species at pH 7.3.


dehydroisoandrosterone 3-glucuronide

A steroid glucosiduronic acid having dehydroepiandrosterone as the steroid component.


phenazopyridine

A diaminopyridine that is 2,6-diaminopyridine substituted at position 3 by a phenylazo group. A local anesthetic that has topical analgesic effect on mucosa lining of the urinary tract. Its use is limited by problems with toxicity (primarily blood disorders) and potential carcinogenicity.


A 3-oxo Delta(4)-steroid that is progesterone which has been oxidised to introduce a double bond between positions 1 and 2.


name: RS27_HUMAN Small ribosomal subunit protein eS27 (sprot)

description: A small ribosomal subunit protein eS27 that is encoded in the genome of human.


name: 4-(4-Acryloylamino-benzenesulfonyl)-piperazine-1-carboxylic acid tert-butyl ester


name: [1-(4-Acryloylamino-benzenesulfonyl)-piperidin-4-yl]-carbamic acid benzyl ester


name: 4-[4-(Acryloyl-methyl-amino)-benzenesulfonyl]-piperazine-1-carboxylic acid tert-butyl ester


name: 4-(4-Acryloylamino-benzenesulfonylamino)-piperidine-1-carboxylic acid benzyl ester


name: 4-(4-(Z)-But-2-enoylamino-benzenesulfonyl)-piperazine-1-carboxylic acid tert-butyl ester


name: 4-[4-(1-Oxo-but-2-ynylamino)-benzenesulfonyl]-piperazine-1-carboxylic acid tert-butyl ester


name: 4-(4-Acryloylamino-2-methoxy-benzenesulfonyl)-piperazine-1-carboxylic acid tert-butyl ester


name: 4-(4-Acryloylamino-2-trifluoromethyl-benzenesulfonyl)-piperazine-1-carboxylic acid benzyl ester


name: 4-(4-Acryloylamino-benzenesulfonyl)-piperazine-1-carboxylic acid 2-chloro-benzyl ester


name: 4-(4-Acryloylamino-benzenesulfonyl)-piperazine-1-carboxylic acid benzyl ester


A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 7-fluoro-3-[(2-fluoro-4-iodophenyl)amino]furo[3,2-c]pyridine-2-carboxylic acid with the amino group of (2S)-1-(aminooxy)propan-2-ol.


name: ACK1_MOUSE Activated CDC42 kinase 1 (sprot)

description: An activated CDC42 kinase 1 that is encoded in the genome of mouse.


name: FUT10_HUMAN Alpha-(1,3)-fucosyltransferase 10 (sprot)

description: An alpha-(1,3)-fucosyltransferase 10 that is encoded in the genome of human.


name: ERMA_STAAN rRNA adenine N-6-methyltransferase (sprot)


name: ERMC1_STAAU rRNA adenine N-6-methyltransferase (sprot)


name: TNF11_HUMAN Tumor necrosis factor ligand superfamily member 11 (sprot)

description: A tumor necrosis factor ligand superfamily member 11 that is encoded in the genome of human.


minocycline

A tetracycline analogue having a dimethylamino group at position 7 and lacking the methyl and hydroxy groups at position 5.


cefpirome

A fourth-generation cephalosporin antibiotic having 6,7-dihydro-5H-cyclopenta[b]pyridinium-1-ylmethyl and [(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino side groups located at positions 3 and 7 respectively.


cefapirin

A cephalosporin with  acetoxymethyl and 2(pyridin-4-ylsulfanyl)acetamido substituents at positions 3 and 7, respectively, of the cephem skeleton. It is used (as its sodium salt) as an antibiotic, being effective against gram-negative and gram-positive organisms.


name: GLUPH_PLAF7 Bifunctional glucose-6-phosphate 1-dehydrogenase/6-phosphogluconolactonase (sprot)


CALX_HUMAN Calnexin (sprot)

A calnexin that is encoded in the genome of human.


isosarcodine

A steroid alkaloid that is 5alpha-pregnane substituted by an acetyl(methyl)amino group at position 3beta, a methyl group at position 20S, and a dimethylamino group at position 21.


fumagillin

A meroterpenoid resulting from the formal condensation of the hydroxy group of fumagillol with the carboxylic acid group of (all-E)-deca-2,4,6,8-tetraenedioic acid. Originally isolated from the fungus Aspergillus fumigatus, it is used for the control of Nosema infection in honey bees.


all-trans-retinal

A retinal in which all four exocyclic double bonds have E- (trans-) geometry.


name: NR4A2_MOUSE Nuclear receptor subfamily 4 group A member 2 (sprot)

description: A nuclear receptor subfamily 4 group A member 2 that is encoded in the genome of mouse.


name: NR4A2_RAT Nuclear receptor subfamily 4 group A member 2 (sprot)

description: A nuclear receptor subfamily 4 group A member 2 that is encoded in the genome of rat.


name: UCK1_MOUSE Uridine-cytidine kinase 1 (sprot)

description: A uridine-cytidine kinase 1 that is encoded in the genome of mouse.


An optically active form of 15-HETE having 15(S)-configuration..


name: PARP8_HUMAN Protein mono-ADP-ribosyltransferase PARP8 (sprot)

description: A protein mono-ADP-ribosyltransferase PARP8 that is encoded in the genome of human.


name: LDHB_PIG L-lactate dehydrogenase B chain (sprot)

description: An L-lactate dehydrogenase B chain that is encoded in the genome of pig.


betamethasone dipropionate

A steroid ester that is betamethasone in which the hydroxy hydrogens at positions 17 and 21 are replaced by propanoyl groups. It is used in combination with calcipotriene hydrate, a synthetic vitamin D analogue, for the topical treatment of plaque psoriasis in adult patients.


surfactin B

A cyclodepsipeptide that is N-[(3R)-3-hydroxy-12-methyltridecanoyl]-L-alpha-glutamyl-L-leucyl-D-leucyl-L-valyl-L-alpha-aspartyl-D-leucyl-L-leucine in which the C-terminal carboxy group has been lactonised by condensation with the alcoholic hydroxy group.


L-alanine

The L-enantiomer of alanine.


name: [[(2S,3R,4S,5S)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate


name: Carbamic acid, [(1S,2S)-2-hydroxy-1-[(4-hydroxyphenyl)methyl]-2-[(1R,2R)-2-[[(phenylmethyl)amino]carbonyl]cyclopentyl]ethyl]-, 1,1-dimethylethyl ester


name: Acetic acid 4-phenyl-4H-benzo[b]pyrrolo[1,2-d][1,4]thiazin-4-yl ester


name: Acetic acid 4-(4-methoxy-phenyl)-4H-benzo[b]pyrrolo[1,2-d][1,4]thiazin-4-yl ester


An aminoalkylpyridine that is pyridine substituted by a ethanamino group at position 2.


brivaracetam

A non-proteinogenic amino acid derivative that is butanamide in which the pro-S hydrogen at position 2 is replaced by a (4R)-2-oxo-4-propylpyrrolidin-1-yl. Used for treatment of partial onset seizures related to epilepsy.


levetiracetam

A pyrrolidinone and carboxamide that is N-methylpyrrolidin-2-one in which one of the methyl hydrogens is replaced by an aminocarbonyl group, while another is replaced by an ethyl group (the S enantiomer). An anticonvulsant, it is used for the treatment of epilepsy in both human and veterinary medicine.


name: 3-[4-(2,6-dichlorobenzoyl amino)phenyl]-2-{3-[(2,2-dimethylpropionyl)isobutyl amino]phenyl}propionic Acid


cefodizime

A cephalosporin compound having 5-(carboxymethyl)-4-methyl-1,3-thiazol-2-yl]sulfanyl}methyl and [2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino side groups located at positions 3 and 7 respectively.


name: TBB4B_HUMAN Tubulin beta-4B chain (sprot)

description: A tubulin beta-4B chain that is encoded in the genome of human.


cenicriviroc

A member of the class of benzazocines that is (5Z)-1,2,3,4-tetrahydro-1-benzazocine which is substituted by a 2-methylpropyl, N-{4-[(S)-(1-propyl-1H-imidazol-5-yl)methanesulfinyl]phenyl}carboxamide and 4-(2-butoxyethoxy)phenyl groups at positions 1, 5 and 8, respectively. It is a potent chemokine 2 and 5 receptor antagonist currently in development for the treatment of liver fibrosis in adults with nonalcoholic steatohepatitis (NASH).


iodocyanopindolol

An indole that is 1H-indole substituted at positions 2, 3 and 7 by cyano, iodo and 3-(tert-butylamino)-2-hydroxypropoxy groups respectively.


name: NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE


name: 4-Methyl-3-(morpholine-4-sulfonyl)-benzoic acid 2-methoxy-phenyl ester


A hydroxypregnenolone carrying an alpha-hydroxy group at position 17.


A C19-steroid that is testosterone in which the hydrogen at the 16alpha position has been replaced by a hydroxy group.


A 3-hydroxy steroid that is obtained by formal dehydrogenation across positions 7 and 8 of 17beta-estradiol.


A 3-hydroxy steroid that is obtained by formal dehydrogenation across positions 6 and 7 of 17beta-estradiol.


A deoxycortisol that is cortisol in which the hydroxy group at position 11 has been replaced by a hydrogen.


EQUILENIN

A 3-hydroxy steroid that is estrone which carries two double bonds at positions 6 and 8. It is found in the urine of pregnant mare's and extensively used for estrogen replacement therapy in postmenopausal women.


SITOGLUSIDE

A steroid saponin that is sitosterol attached to a beta-D-glucopyranosyl residue at position 3 via a glycosidic linkage. It has bee isolated from Panax japonicus var. major and Breynia fruticosa.


cepharanthine

A bisbenzylisoquinoline alkaloid from tubers of Stephania; stimulates recovery of immunologic function in lymphatic system after administration of antineoplastic agents or x-irradiation.


D-galactose

D-Galactopyranose having alpha-configuration at the anomeric centre.


name: NQO1_RAT NAD(P)H dehydrogenase [quinone] 1 (sprot)

description: An NAD(P)H dehydrogenase [quinone] 1 that is encoded in the genome of rat.


CYSK_HAEIN Cysteine synthase (sprot)

A cysteine synthase A that is encoded in the genome of Haemophilus influenzae Rd KW20.


menatetrenone

A menaquinone whose side-chain contains 4 isoprene units in an all-trans-configuration.


name: PUNA_MYCTU Purine nucleoside phosphorylase (sprot)

description: A purine nucleoside phosphorylase that is encoded in the genome of Mycobacterium tuberculosis H37Rv.


name: FPR1_MOUSE fMet-Leu-Phe receptor (sprot)

description: An fMet-Leu-Phe receptor that is encoded in the genome of mouse.


TECHTOCHRYSIN

A monohydroxyflavone that is  flavone substituted by a hydroxy group at position 4 and a methoxy group at position 7 respectively.


A trihydroxyflavone that is galangin substituted by a 1,1-dimethylallyl moiety at position 8. It is isolated from the buds of Platanus acerifolia.


A monomethoxyflavone that is galangin in which the hydroxy group at position 3 has been replaced by a methoxy group.


A 7-hydroxyflavonol that is kaempferide substituted by a 1,1-dimethylallyl group at position 8.


A  para-terphenyl that is the 3,3''-dihydroxy derivative of  terphenyllin. It has been isolated from Aspergillus taichungensis.


PRENYLTERPHENYLLIN

A para-terphenyl that is 1,1':4',1''-terphenyl substituted by methoxy groups at positions 3' and 6', a prenyl group at position 3 and hydroxy groups at positions 2', 4 and 4''. Isolated from the fungus, Aspergillus taichungensis, it exhibits cytotoxic activity.


TERPHENYLLIN

A para-terphenyl that is 1,1':4',1''-terphenyl substituted by methoxy groups at positions 3' and 6' and hydroxy groups at positions 2', 4 and 4''. It has been isolated from Aspergillus taichungensis.


A para-terphenyl that is the 3-hydroxy derivative of  terphenyllin. It has been isolated from Aspergillus taichungensis.


A para-terphenyl that is the 4''-deoxy derivative of  terphenyllin. It has been isolated from Aspergillus taichungensis.


benznidazole

A monocarboxylic acid amide obtained by formal condensation of the carboxy group of (2-nitroimidazol-1-yl)acetic acid with the aromatic amino group of benzylamine. Used for treatment of Chagas disease.


ombitasvir

A dipeptide derivative which is used which is in combination with dasabuvir sodium hydrate, paritaprevir and ritonavir (under the trade name Viekira Pak) for treatment of chronic hepatitis C virus genotype 1 infection as well as cirrhosis of the liver.


An undecaprenyl-diphosphatase that is encoded in the genome of Escherichia coli K-12.


name: UPPS_ECOLI Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) (sprot)

description: A ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) that is encoded in the genome of Escherichia coli K-12.


bacitracin A

A mixture of at least nine closely related homodetic cyclic peptides produced by Bacillus subtilis and B. licheniformis, which is particularly active against Gram-positive bacteria.


SYS_ECOLI Serine--tRNA ligase (sprot)

A serine--tRNA ligase that is encoded in the genome of Escherichia coli K-12.


SYY_ECOLI Tyrosine--tRNA ligase (sprot)

A tyrosyl-tRNA synthetase that is encoded in the genome of Escherichia coli K-12.


name: MYC_HUMAN Myc proto-oncogene protein (sprot)

description: A c-myc protein that is encoded in the genome of human.


name: EBPL_HUMAN Emopamil-binding protein-like (sprot)

description: An emopamil-binding protein-like that is encoded in the genome of human.


(S)-nandinine

A berberine alkaloid that is 5,8,13,13a-tetrahydro-2H,6H-[1,3]dioxolo[4,5-g]isoquinolino[3,2-a]isoquinoline carrying hydroxy and methoxy substituents at positions 9 and 10 respectively.


name: GSK3_DICDI Glycogen synthase kinase-3 (sprot)

description: A glycogen synthase kinase 3 that is a translation product of the gskA gene in Dictyostelium discoideum.


name: 2,6-Diazatricyclo[3.3.1.13,7]decane-2-carboxylic acid, 6-[6-[2-fluoro-4-(1H-tetrazol-1-yl)phenoxy]-5-Methyl-4-pyriMidinyl]-, 1-Methylcyclopropyl ester


CHLORIMURON ETHYL

An ethyl ester resulting from the formal condensation of the carboxy group of chlorimuron with ethanol. A proherbicide for chloimuron, it is used as herbicide for the control of broad-leaved weeds in peanuts, soya beans, and other crops.


TRIBENURON METHYL

The methyl ester of tribenuron.


ETHAMETSULFURON METHYL

A methyl ester resulting from the formal condensation of the carboxy group of ethametsulfuron with methanol. A herbicide used for the control of broad-leaved weeds in oil seed rape and fodder rape.


SULFOMETURON METHYL

A benzoate ester that is the methyl ester of 2-{[(4,6-dimethylpyrimidin-2-yl)carbamoyl]sulfamoyl}benzoic acid.


CHLORSULFURON

An N-sulfonylurea that is N-carbamoyl-2-chlorobenzenesulfonamide in which one of the hydrogens attached to the non-sulfonylated nitrogen has been replaced by a 4-methoxy-6-methyl-1,3,5-triazin-2-yl group. A herbicide used for the control of broadleaf weeds in wheat, barley and oats.


BENSULFURON METHYL

The methyl ester of bensulfuron. An acetolactate synthase inhibitor, it is used as a herbicide for the control of a variety of both annual and perennial weeds in crops, particularly wheat and rice. It is not licensed for use within the UK.


vecuronium

A 5alpha-androstane compound having 3alpha-acetoxy-, 17beta-acetoxy-, 2beta-piperidino- and 16beta-N-methylpiperidinium substituents.


noscapine

A benzylisoquinoline alkaloid that is 1,2,3,4-tetrahydroisoquinoline which is substituted by a 4,5-dimethoxy-3-oxo-1,3-dihydro-2-benzofuran-1-yl group at position 1, a methylenedioxy group at positions 6-7 and a methoxy group at position 8. Obtained from plants of the Papaveraceae family, it lacks significant painkilling properties and is primarily used for its antitussive (cough-suppressing) effects.


(R)-selisistat

A 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide that has R configuration. It is the inactive enantiomer.


name: SYT_YERPE Threonine--tRNA ligase (sprot)

description: A protein that is a translation product of the thrS gene in Yersinia pestis.


(R)-nomifensine

The R enantiomer of nomifensine.


cabergoline

An N-acylurea that is (8R)-ergoline-8-carboxamide in which the hydrogen attached to the piperidine nitrogen (position 6) is substituted by an allyl group and the hydrogens attached to the carboxamide nitrogen are substituted by a 3-(dimethylamino)propyl group and an N-ethylcarbamoyl group. A dopamine D2 receptor agonist, cabergoline is used in the management of Parkinson's disease and of disorders associated with hyperprolactinaemia.


name: KCNQ5_HUMAN Potassium voltage-gated channel subfamily KQT member 5 (sprot)

description: A voltage-gated potassium channel subunit KCNQ5 that is encoded in the genome of human.


name: KCNQ3_HUMAN Potassium voltage-gated channel subfamily KQT member 3 (sprot)

description: A voltage-gated potassium channel subunit KCNQ3 that is encoded in the genome of human.


name: KCNJ4_HUMAN Inward rectifier potassium channel 4 (sprot)

description: An inward rectifier potassium channel 4 that is encoded in the genome of human.


name: KCNC1_RAT Potassium voltage-gated channel subfamily C member 1 (sprot)

description: A voltage-gated potassium channel KCNC1 that is encoded in the genome of rat.


name: UBA7_HUMAN Ubiquitin-like modifier-activating enzyme 7 (sprot)

description: A ubiquitin-like modifier-activating enzyme 7 that is encoded in the genome of human.


name: B3GT1_HUMAN Beta-1,3-galactosyltransferase 1 (sprot)

description: A beta-1,3-galactosyltransferase 1 that is encoded in the genome of human.


CROTONIC ACID

A but-2-enoic acid with a trans- double bond at C-2. It has been isolated from Daucus carota.


trans-3-coumaric acid

A 3-coumaric acid that is phenol substituted with trans-2-propenoic acid at position C-3.


meso-tartaric acid

A 2,3-dihydroxybutanedioic acid that has meso configuration.


name: CYSK_MYCTU O-acetylserine sulfhydrylase (sprot)

description: A cysteine synthase A that is encoded in the genome of Mycobacterium tuberculosis H37Rv.


name: BGAT_HUMAN Histo-blood group ABO system transferase (sprot)

description: A histo-blood group ABO system transferase that is encoded in the genome of human.


name: SDIS_PSEPU Steroid Delta-isomerase (sprot)


name: SH21A_HUMAN SH2 domain-containing protein 1A (sprot)

description: An SH2 domain-containing protein 1A that is encoded in the genome of human.


name: HGF_HUMAN Hepatocyte growth factor (sprot)

description: A hepatocyte growth factor that is encoded in the genome of human.


ethyl hydroxybenzoate

An ethyl ester resulting from the formal condensation of the carboxy group of 4-hydroxybenzoic acid with ethanol,


methyl p-hydroxybenzoate

A 4-hydroxybenzoate ester resulting from the formal condensation of the carboxy group of 4-hydroxybenzoic acid with methanol. It is the most frequently used antimicrobial preservative in cosmetics. It occurs naturally in several fruits, particularly in blueberries.


An aminophenol that is one of three amino derivatives of phenol which has the single amino substituent located meta to the phenolic -OH group.


ethyl 3,4-dihydroxybenzoate

An ethyl ester resulting from the formal condensation of the carboxy group of 3,4-dihydroxybenzoic acid with ethanol. It is the anti-oxidative component of peanut seed testa.


FRAXINE

A beta-D-glucoside that is fraxetin attached to a beta-D-glucopyranosyl group at position 8 via a glycosidic linkage. It is a natural product isolated from the leaves of Fraxinus excelsior and exhibits potent hepatoprotective effects in vitro and in vivo.


SCOPOLIN

A member of the class of  coumarins that is scopoletin attached to a beta-D-glucopyranosyl residue at position 7 via a glycosidic linkage.


name: GGYF2_HUMAN GRB10-interacting GYF protein 2 (sprot)

description: A GRB10-interacting GYF protein 2 that is encoded in the genome of human.


name: N,N'-Sulfonyl Bis-L-valine Dimethyl Ester


name: N,N'-Sulfonyl Bis-L-alanine Dimethyl Ester


An L-phenylalanine derivative that is N-(2,6-dichlorobenzoyl)-L-phenylalanine carrying an additional 1,6-dimethyl-2-oxo-4-(trifluoromethyl)-1,2-dihydropyridin-3-yl substituent at position 4 on the phenyl ring.


name: ACER2_HUMAN Alkaline ceramidase 2 (sprot)

description: An alkaline ceramidase 2 that is encoded in the genome of human.


name: VGFR2_DANRE Vascular endothelial growth factor receptor 2 (sprot)

description: A vascular endothelial growth factor receptor 2 that is encoded in the genome of zebrafish.


name: PPT1_HUMAN Palmitoyl-protein thioesterase 1 (sprot)

description: A palmitoyl-protein thioesterase 1 that is encoded in the genome of human.


name: LPAR6_HUMAN Lysophosphatidic acid receptor 6 (sprot)

description: An oleoyl-L-alpha-lysophosphatidic acid receptor that is encoded in the genome of human.


1-palmitoyl-sn-glycerol 3-phosphate

A 1-acyl-sn-glycerol 3-phosphate having palmitoyl as the acyl group.


A member of the class of quinazolines that is quinazoline which is substituted by a {4-[(2-methoxyethyl)carbamoyl]phenyl}nitrilo group and a pyridin-4-yl group at positions 2 and 6, respectively. It is a B-Raf and MKNK2 kinase inhibitor.


OROXYLIN A

A dihydroxy- and monomethoxy-flavone in which the hydroxy groups are positioned at C-5 and C-7 and the methoxy group is at C-6.


name: TMPS4_HUMAN Transmembrane protease serine 4 (sprot)

description: A transmembrane protease serine 4 that is encoded in the genome of human.


A sulindac-based non-steroidal anti-inflammatory drug.


BAY 60-6583

A member of the class of cyanopyridines that is 6-amino-3,5-dicyano-4-(4-hydroxyphenyl)-2-sulfanylpyridine in which the hydroxy and sulfanyl hydrogens are replaced by cyclopropylmethyl and carboxamidomethyl groups respectively.


name: SC5A5_RAT Sodium/iodide cotransporter (sprot)

description: A sodium/iodide cotransporter that is encoded in the genome of rat.


BENTHIAVALICARB-ISOPROPYL

A carbamate ester that is the isopropyl ester of benthiavalicarb. It is used as an agricultural fungicide.


A dihydroxypyridine in which the two hydroxy groups are located at positions 2 and 3.


OXDA_MOUSE D-amino-acid oxidase (sprot)

A D-amino-acid oxidase that is encoded in the genome of mouse.


name: RIR1_MYCTU Ribonucleoside-diphosphate reductase subunit alpha (sprot)

description: A ribonucleoside-diphosphate reductase large subunit that is encoded in the genome of Mycobacterium tuberculosis H37Rv.


3,5-DIIODOTHYROPROPIONIC ACID

A monocarboxylic acid that is (4-hydroxy-3,5-diiodophenyl)propanoic acid in which the phenolic hydroxy group has been replaced by a 4-hydroxyphenyl group. An ionotropic analogue of L-thyroxine.


UR2R_MOUSE Urotensin-2 receptor (sprot)

A urotensin-2 receptor that is encoded in the genome of mouse.


name: 3-[3-(3,3-Diphenylpropyl)-3-(2-morpholin-4-ylethyl)ureido]benzoic acid isopropyl ester


dabigatran etexilate

An aromatic amide obtained by formal condensation of the carboxy group of 2-{[(4-{N'-[(hexyloxy)carbonyl]carbamimidoyl}phenyl)amino]methyl}-1-methyl-1H-benzimidazole-5-carboxylic acid with the secondary amino group of ethyl N-pyridin-2-yl-beta-alaninate. A prodrug for dabigatran, a thrombin inhibitor and anticoagulant which is used for the prevention of stroke and systemic embolism.


name: 4-[[[3,5-Bis(trifluoromethyl)benzyl]oxy]methyl]-4-phenylpiperidine-1-carboxylic acid tert-butyl ester


name: R1AB_FIPV Replicase polyprotein 1ab (sprot)


vamorolone

A 3-oxo-Delta(1),Delta(4)-steroid that is pregna-1,4,9(11)-trien-17-ol substituted by oxo, oxo, and hydroxy groups at positions 3, 20, and 21, respectively. It is approved by the FDA for the treatment of patients with Duchenne muscular dystrophy aged 2 years and older.


name: CX3C1_HUMAN CX3C chemokine receptor 1 (sprot)

description: A CX3C chemokine receptor 1 that is encoded in the genome of human.


(R)-econazole

A 1-{2-(4-chlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl}imidazole that is the (R)-enantiomer of econazole.


Vitamin E

An alpha-tocopherol that has R,R,R configuration. The naturally occurring stereoisomer of alpha-tocopherol, it is found particularly in sunflower and olive oils.


DINITROCHLOROBENZENE

A C-nitro compound that is chlorobenzene carrying a nitro substituent at each of the 2- and 4-positions.


name: TSPOB_HUMAN Putative peripheral benzodiazepine receptor-related protein (sprot)


P2RX1_MOUSE P2X purinoceptor 1 (sprot)

A P2X purinoceptor 1 that is encoded in the genome of mouse.


hydrogenvanadate

A divalent inorganic anion obtained by removal of two protons from vanadic acid.


name: MGAT2_MOUSE Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (sprot)

description: An alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase that is encoded in the genome of mouse.


pyrrole-2-carboxylic acid

A pyrrolecarboxylic acid that is 1H-pyrrole carrying a carboxy substituent at position 2.


name: MYB_CHICK Transcriptional activator Myb (sprot)

description: A myb proto-oncogene protein that is encoded in the genome of chicken.


COSTUNOLIDE

A germacranolide with anthelminthic, antiparasitic and antiviral activities.


HELENINE

A sesquiterpene lactone that is 3a,5,6,7,8,8a,9,9a-octahydronaphtho[2,3-b]furan-2-one bearing two methyl substituents at positions 5 and 8a as well as a methylidene substituent at position 3.


ISOALANTOLACTONE

A sesquiterpene lactone of the eudesmanolide group. It has been isolated from Inula helenium.


ARGLABIN

An organic heterotetracyclic compound and guaianolide sesquiterpene lactone that is acrylic acid which is substituted at position 2 by a 4-hydroxy-3,8-dimethyl-1,3a,4,5,6,7-hexahydroazulen-5-yl group in which the double bond in the 7-membered ring has been epoxidised and in which the hydroxy group and the carboxy group have undergone formal condensation to give the corresponding gamma-lactone. It is found in Artemisia glabella. Arglabin-DMA HCl, the hydrochloride salt of the adduct resulting from the conjugate addition of dimethylamine to the ene-lactone moiety, has been successfully used in Khazakhstan for the treatment of breast, colon, ovarian and lung cancers.


An aromatic amide obtained by formal condensation of the amino group of 2-(6-methoxy-1-oxo-1,3-dihydro-2H-isoindol-2-yl)-1,3-thiazole-4-carboxylic acid with the primary amino group of 4-(piperazin-1-yl)pyridin-3-amine.


name: Benzoic acid [(2S)-1-methylpyrrolidine-2-yl]methyl ester


TETRAHYDRODEMETHOXYCURCUMIN

A beta-diketone that is tetrahydrocurcumin in which one the methoxy groups has been replaced by a hydrogen atom.


name: p53 and MDM2 proteins-interaction-inhibitor chiral


name: TRPV6_HUMAN Transient receptor potential cation channel subfamily V member 6 (sprot)

description: A transient receptor potential cation channel subfamily V member 6 that is encoded in the genome of human.


name: BMP4_MOUSE Bone morphogenetic protein 4 (sprot)

description: A bone morphogenetic protein 4 that is encoded in the genome of mouse.


CD81_HUMAN CD81 antigen (sprot)

A CD81 molecule that is encoded in the genome of human.


name: NTCP2_RAT Ileal sodium/bile acid cotransporter (sprot)

description: An ileal sodium/bile acid cotransporter that is encoded in the genome of rat.


name: GPR18_HUMAN N-arachidonyl glycine receptor (sprot)

description: An N-arachidonyl glycine receptor that is encoded in the genome of human.


A diadenosyl pentaphosphate having the two 5'-adenosyl residues attached at the P(1)- and P(5)-positions.


UT1_HUMAN Urea transporter 1 (sprot)

A urea transporter 1 that is encoded in the genome of human.


name: TRXB_MYCTU Thioredoxin reductase (sprot)

description: A thioredoxin reductase that is encoded in the genome of Mycobacterium tuberculosis H37Rv.


name: GPR35_MOUSE G-protein coupled receptor 35 (sprot)

description: A G-protein coupled receptor 35 that is encoded in the genome of mouse.


zavegepant

A member of the class of ureas that is urea in which both amino groups are replaced by 4-(2-oxo-1,2-dihydroquinolin-3-yl)piperidin-1-yl and {(2R)-3-(7-methyl-1H-indazol-5-yl)-1-[4-(1-methylpiperidin-4-yl)piperazin-1-yl]-1-oxopropan-2-yl}amino groups. It is a calcitonin gene-related peptide receptor antagonist whose hydrochloride salt has been approved by the FDA for the acute treatment of migraine.


name: UBP21_HUMAN Ubiquitin carboxyl-terminal hydrolase 21 (sprot)

description: A ubiquitin carboxyl-terminal hydrolase 21 that is encoded in the genome of human.


R,R-THC

A carbotetracyclic compound that is 5,6,11,12-tetrahydrochrysene substituted by hydroxy groups at positions 2 and 8 and by ethyl groups at positions 5 and 11 (the 5R,11R-stereoisomer). It is an agonist of ER-alpha and antagonist of ER-beta receptors.


flutrimazole

An imidazole antifungal agent that is imidazole in which the hydrogen attached to the nitrogen is replaced by a 2,4'-difluorotrityl group. A topical antifungal agent which displays potent broad-spectrum in vitro activity against dermatophytes, filamentous fungi and yeasts.


name: DUS15_HUMAN Dual specificity protein phosphatase 15 (sprot)

description: A dual specificity protein phosphatase 15 that is encoded in the genome of human.


name: AAPK2_RAT 5'-AMP-activated protein kinase catalytic subunit alpha-2 (sprot)

description: A 5'-AMP-activated protein kinase catalytic subunit alpha-2 that is encoded in the genome of rat.


name: ETV6_HUMAN Transcription factor ETV6 (sprot)

description: A transcription factor ETV6 that is encoded in the genome of human.


An N-acylneuraminate-9-phosphatase that is encoded in the genome of human.


name: TTLL7_MOUSE Tubulin polyglutamylase TTLL7 (sprot)

description: A tubulin polyglutamylase TTLL7 that is encoded in the genome of mouse.


PRIO_SHEEP Major prion protein (sprot)

A major prion protein that is encoded in the genome of sheep.


MYG_HUMAN Myoglobin (sprot)

A myoglobin that is encoded in the genome of human.


name: UBP4_HUMAN Ubiquitin carboxyl-terminal hydrolase 4 (sprot)

description: A ubiquitin carboxyl-terminal hydrolase 4 that is encoded in the genome of human.


name: USP9X_HUMAN Ubiquitin carboxyl-terminal hydrolase 9X (sprot)

description: A probable ubiquitin carboxyl-terminal hydrolase FAF-X that is encoded in the genome of human.


name: [5-(3-Isopropyl-phenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]-carbamic acid methyl ester


name: Cyclohexaneacetic acid, 4-[4-(4-amino-7,8-dihydro-5-oxopyrimido[5,4-f][1,4]oxazepin-6(5H)-yl)phenyl]-, methyl ester, trans-


name: L-Alanine, N-[4-amino-3-[[(2S)-2-amino-1-oxo-4-phenylbutyl]amino]benzoyl]-, methyl ester


name: TNR6_RAT Tumor necrosis factor receptor superfamily member 6 (sprot)

description: A tumor necrosis factor receptor superfamily member 6 that is encoded in the genome of rat.


name: 2-[[1-oxo-2-(phenylthio)ethyl]amino]benzoic acid methyl ester


name: MAST3_HUMAN Microtubule-associated serine/threonine-protein kinase 3 (sprot)

description: A microtubule-associated serine/threonine-protein kinase 3 that is encoded in the genome of human.


aureusidin 6-O-beta-glucoside

A beta-D-glucoside in which a beta-D-glucopyranosyl residue is attached at position 6 of aureusidin via a glycosidic linkage.


name: NPC1_HUMAN NPC intracellular cholesterol transporter 1 (sprot)

description: An NPC intracellular cholesterol transporter 1 that is encoded in the genome of human.


name: PPIC_HUMAN Peptidyl-prolyl cis-trans isomerase C (sprot)

description: A eukaryotic-type peptidyl-prolyl cis-trans isomerase C that is encoded in the genome of human.


4-CHLORO CHALCONE

A member of the class of  chalcones that is trans-chalcone substituted by a chloro group at position 4.


name: OX2R_MOUSE Orexin receptor type 2 (sprot)

description: An orexin receptor type 2 that is encoded in the genome of mouse.


name: OX1R_MOUSE Orexin/Hypocretin receptor type 1 (sprot)

description: An orexin/hypocretin receptor type 1 that is encoded in the genome of mouse.


name: M3K11_MOUSE Mitogen-activated protein kinase kinase kinase 11 (sprot)

description: A mitogen-activated protein kinase kinase kinase 11 that is encoded in the genome of mouse.


tacalcitol

A hydroxy seco-steroid that is calciol which carries hydroxy groups at positions 1S and 24R. It is a vitamin D3 analog which is used for the treatment of psoriasis vulgaris in adults, especially on the scalp.


CYH2_HUMAN Cytohesin-2 (sprot)

A cytohesin-2 that is encoded in the genome of human.


A pyrrolopyrimidine that is 7-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine which has been substituted at position 5 by a 4-fluoro-2,3-dihydro-1H-indol-5-yl group, the nitrogen of which has been acylated by a (6-methylpyridin-2-yl)acetyl group. An orally bioavailable PERK inhibitor.


A 11beta-hydroxy steroid that is  progesterone substituted by a beta-hydroxy group at position 11.


name: ADRB1_PIG Beta-1 adrenergic receptor (sprot)

description: A beta-1 adrenergic receptor that is encoded in the genome of pig.


name: RET_RAT Proto-oncogene tyrosine-protein kinase receptor Ret (sprot)

description: A proto-oncogene tyrosine-protein kinase receptor Ret that is encoded in the genome of rat.


name: DDR1_RAT Epithelial discoidin domain-containing receptor 1 (sprot)

description: A protein that is a translation product of the Ddr1 gene in rat.


OLIGOMYCIN

An oligomycin with formula C45H74011. An inhibitor of mitochondrial F1FO ATP synthase that induces apoptosis in a variety of cell types and exhibits antifungal, antitumour, and nematicidal activities, but its clinical application has been limited by poor solubility in water and other biocompatible solvents.


name: KCNH2_CANLF Potassium voltage-gated channel subfamily H member 2 (sprot)


4-aminobenzenesulfonic acid

An  aminobenzenesulfonic acid that is aniline sulfonated at the para-position.


name: ISPF_BURPS 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase (sprot)


A diester resulting from the formal condensation of the two hydroxy groups of 3-fluorocatechol with the carboxy groups of 3-hydroxybenzoic acid. It is an inhibitor of glucose transporter 1 (GLUT1) that suppresses tumour growth in mouse xenograft models.


name: Propanoic acid, 2,2-dimethyl-, 6-[(2-benzoxazolylthio)methyl]-4-oxo-4H-pyran-3-yl ester


name: S47A1_MOUSE Multidrug and toxin extrusion protein 1 (sprot)

description: A multidrug and toxin extrusion protein 1 that is encoded in the genome of mouse.


name: 3-[(2-Methoxy-7-oxo-7,8-dihydro-pyrido[2,3-d]pyrimidine-6-carbonyl)-amino]-4-methyl-benzoic acid methyl ester


name: 3-[(6,7-Dimethoxy-2-oxo-1,2-dihydro-quinoline-3-carbonyl)-amino]-4-methyl-benzoic acid methyl ester


1,3-Benzothiazole substituted at the 2-position with a sulfanyl group.


BENZO[D]THIAZOLE

An organic heterobicyclic compound that is a fusion product between benzene and thiazole. The parent of the class of benzothiazoles.


FUBERIDAZOLE

A ring assembly consisting of benzimidazole substituted at position 2 by a 2-furyl group.  A fungicide used as a seed treatment to control Fusarium spp. in cereals.


SRR_SCHPO Serine racemase (sprot)

A serine racemase that is encoded in the genome of Schizosaccharomyces pombe 972h-.


name: CXB2_HUMAN Gap junction beta-2 protein (sprot)

description: A gap junction beta-2 protein that is encoded in the genome of human.


name: FPTA_PSEAE Fe(3+)-pyochelin receptor (sprot)


name: Orexin A (17-33) trifluoroacetate salt H-Tyr-Glu-Leu-Leu-His-Gly-Ala-Gly-Asn-His-Ala-Ala-Gly-Ile-Leu-Thr-Leu-NH2 trifluoroacetate salt


name: PFKA_TRYCC ATP-dependent 6-phosphofructokinase (sprot)


An aza-steroid that is 3-O-methyl-17beta-estradiol in which the 17beta-hydroxy group is replaced by a 6-(maleimid-1-yl)hexylamino group. An inibitor of phospholipase C.


name: TERT_RAT Telomerase reverse transcriptase (sprot)

description: A telomerase reverse transcriptase that is encoded in the genome of rat.


name: 3HAO_HUMAN 3-hydroxyanthranilate 3,4-dioxygenase (sprot)

description: A 3-hydroxyanthranilate 3,4-dioxygenase that is encoded in the genome of human.


name: 3HAO_RAT 3-hydroxyanthranilate 3,4-dioxygenase (sprot)

description: A 3-hydroxyanthranilate 3,4-dioxygenase that is encoded in the genome of rat.


name: ACACA_MOUSE Acetyl-CoA carboxylase 1 (sprot)

description: An acetyl-CoA carboxylase 1 that is encoded in the genome of mouse.


name: ACACB_MOUSE Acetyl-CoA carboxylase 2 (sprot)

description: An acetyl-CoA carboxylase 2 that is encoded in the genome of mouse.


name: CLH1_HUMAN Clathrin heavy chain 1 (sprot)

description: A clathrin heavy chain 1 that is encoded in the genome of human.


ITA1_HUMAN Integrin alpha-1 (sprot)

An integrin alpha-1 that is encoded in the genome of human.


name: TYK2_MOUSE Non-receptor tyrosine-protein kinase TYK2 (sprot)

description: A non-receptor tyrosine-protein kinase TYK2 that is encoded in the genome of mouse.


name: TLL2_HUMAN Tolloid-like protein 2 (sprot)

description: A tolloid-like protein 2 that is encoded in the genome of human.


name: CHKB_HUMAN Choline/ethanolamine kinase (sprot)

description: A choline/ethanolamine kinase that is encoded in the genome of human.


name: PPBI_MOUSE Intestinal-type alkaline phosphatase (sprot)

description: A protein that is a translation product of the Akp3 gene in mouse.


name: PPBN_MOUSE Alkaline phosphatase, germ cell type (sprot)

description: An embryonic alkaline phosphatase that is encoded in the genome of mouse.


cobicistat

A monocarboxylic acid amide obtained by formal condensation of the carboxy group of (2S)-2-({[(2-isopropyl-1,3-thiazol-4-yl)methyl](methyl)carbamoyl}amino)-4-(morpholin-4-yl)butanoic acid with the amino group of 1,3-thiazol-5-ylmethyl [(2R,5R)-5-amino-1,6-diphenylhexan-2-yl]carbamate. Acts as a pharmacoenhancer in treatment of HIV-1 by inhibiting P450 enzymes that metabolise other medications..


name: 2,7,10,12-Tetraazatridecanoic acid, 9-(2-aminoethyl)-12-methyl-13-[2-(1-methylethyl)-4-thiazolyl]-8,11-dioxo-3,6-bis(phenylmethyl)-, 5-thiazolylmethyl ester, (3R,6R,9S)-


name: TLL1_HUMAN Tolloid-like protein 1 (sprot)

description: A tolloid-like protein 1 that is encoded in the genome of human.


A member of the class of dihydronaphthalenes that is 1,2-dihydronaphthalene which is substituted at positions 1, 1, 4, and 6 by methyl, methyl, phenylethynyl, and 2-(p-carboxyphenyl)vinyl groups, respectively (the E isomer).


procyanidin B3

A proanthocyanidin consisting of two molecules of (+)-catechin joined by a bond between positions 4 and 8' in alpha-configuration. It can be found in red wine, in barley, in beer, in peach or in Jatropha macrantha, the Huanarpo Macho.


name: ALKB3_HUMAN Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3 (sprot)

description: An alpha-ketoglutarate-dependent dioxygenase alkB homolog 3 that is encoded in the genome of human.


name: GLGE_MYCTU Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase (sprot)


An alkapentaene that is henicos-1-ene with 4 cis double bonds at positions 6,9,12 and 15.


name: ACHE_RAT Acetylcholine receptor subunit epsilon (sprot)

description: An acetylcholine receptor subunit epsilon that is encoded in the genome of rat.


D-mannose

D-Mannose in its six-membered ring form.


alpha-linolenate

A linolenate that is the conjugate base of alpha-linolenic acid, arising from deprotonation of the carboxylic acid group.


elaidate

A long-chain fatty acid anion that is the conjugate base of elaidic acid; shown to exert detrimental effects on mitochondrial lipid composition and function.


petroselinate

An unsaturated fatty acid anion resulting from the deprotonation of the carboxy group of petroselinic acid. The major species at pH 7.3.


(S)-salsolinol

A 1-methyl-1,2,3,4-tetrahydroisoquinoline-6,7-diol that has S-configuration.


name: PDGFA_HUMAN Platelet-derived growth factor subunit A (sprot)

description: A platelet-derived growth factor subunit A that is encoded in the genome of human.


name: DNM3L_HUMAN DNA (cytosine-5)-methyltransferase 3-like (sprot)

description: A DNA (cytosine-5)-methyltransferase 3-like that is encoded in the genome of human.


name: GCKR_RAT Glucokinase regulatory protein (sprot)

description: A glucokinase regulatory protein that is encoded in the genome of rat.


EST1D_MOUSE Carboxylesterase 1D (sprot)

A carboxylesterase 1D that is encoded in the genome of mouse.


A member of the class of indazoles that is 1H-indazole substituted by a 6-(propan-2-yloxy)pyridin-3-yl group at position 3 and by a {[(3S)-3-(methylsulfanyl)-1-(2-{4-[4-(1-methyl-1H-1,2,4-triazol-3-yl)phenyl]-3,6-dihydropyridin-1(2H)-yl}-2-oxoethyl)pyrrolidin-3-yl]carbonyl}amino group at position 5. It is a potent and selective inhibitor of ERK1 and ERK2 in vitro (IC50 values of 23.0 nM and 8.8 nM, respectively). The drug is being developed by Merck Sharp & Dohme and is currently in clinical development for the treatment of advanced/metastatic solid tumors.


name: GPR17_RAT Uracil nucleotide/cysteinyl leukotriene receptor (sprot)

description: A uracil nucleotide/cysteinyl leukotriene receptor that is encoded in the genome of rat.


name: GPR17_MOUSE Uracil nucleotide/cysteinyl leukotriene receptor (sprot)

description: A uracil nucleotide/cysteinyl leukotriene receptor that is encoded in the genome of mouse.


name: TERF2_HUMAN Telomeric repeat-binding factor 2 (sprot)

description: A telomeric repeat-binding factor 2 that is encoded in the genome of human.


dehydrodiconiferyl alcohol

A guaiacyl lignin obtained by cyclodimerisation of coniferol.


lobarin

A member of the class of 2-benzofurans that is 3-butyl-3-hydroxy-2-benzofuran-1(3H)-one substituted by a 3-carboxy-4,6-dihydroxy-2-pentylphenoxy group and a methoxy group at positions 4 and 6, respectively. It is a metabolite isolated from the Sumatran lichen, Stereocaulon halei.


name: NPT2C_HUMAN Sodium-dependent phosphate transport protein 2C (sprot)

description: A sodium-dependent phosphate transport protein 2C that is encoded in the genome of human.


name: S20A1_HUMAN Sodium-dependent phosphate transporter 1 (sprot)

description: A sodium-dependent phosphate transporter 1 that is encoded in the genome of human.


name: NPT2A_RAT Sodium-dependent phosphate transport protein 2A (sprot)

description: A sodium-dependent phosphate transport protein 2A that is encoded in the genome of rat.


name: NPT2A_MOUSE Sodium-dependent phosphate transport protein 2A (sprot)

description: A sodium-dependent phosphate transport protein 2A that is encoded in the genome of mouse.


name: S20A2_HUMAN Sodium-dependent phosphate transporter 2 (sprot)

description: A sodium-dependent phosphate transporter 2 that is encoded in the genome of human.


name: LN28A_MOUSE Protein lin-28 homolog A (sprot)

description: A protein lin-28 homolog A that is encoded in the genome of mouse.


name: ARHG1_HUMAN Rho guanine nucleotide exchange factor 1 (sprot)

description: A Rho guanine nucleotide exchange factor 1 that is encoded in the genome of human.


name: EAA4_RAT Excitatory amino acid transporter 4 (sprot)

description: An excitatory amino acid transporter 4 that is encoded in the genome of rat.


DL-threo-β-hydroxyaspartate

The (3S)-diastereomer of 3-hydroxy-L-aspartic acid.


An alpha-2-macroglobulin that is encoded in the genome of human.


sucralose

A disaccharide derivative consisting of 4-chloro-4-deoxy-alpha-D-galactopyranose and 1,6-dichloro-1,6-dideoxy-beta-D-fructofuranose units linked by a glycosidic bond.


acesulfame

A sulfamate ester that is 1,2,3-oxathiazin-4(3H)-one 2,2-dioxide substituted by a methyl group at position 6.


name: ASM_BOVIN Sphingomyelin phosphodiesterase (sprot)


imetit dihydrobromide

A hydrobromide salt obtained by reaction of imetit with two equivalents of hydrobromic acid. An extremely potent, high affinity agonist at H3 and H4 receptors (Ki values are 0.3 and 2.7 nM respectively). Induces shape change in eosinophils with an EC50 of 25 nM. Centrally active following systemic administration.


blebbistatin

A pyrroloquinoline that is 1,2,3,3a-tetrahydro-H-pyrrolo[2,3-b]quinolin-4-one substituted by a hydroxy group at position 3a, a methyl group at position 6 and a phenyl group at position 1. It acts as an inhibitor of ATPase activity of non-muscle myosin II.


name: MYSN_ACACA Myosin-2 heavy chain, non muscle (sprot)


MYS2_DICDI Myosin-2 heavy chain (sprot)

A myosin type-2 heavy chain 1 that is encoded in the genome of Dictyostelium discoideum.


MYH9_HUMAN Myosin-9 (sprot)

A myosin-9 that is encoded in the genome of human.


MYH10_HUMAN Myosin-10 (sprot)

A myosin-10 that is encoded in the genome of human.


MYH14_MOUSE Myosin-14 (sprot)

A myosin-14 that is encoded in the genome of mouse.


MYH2_HUMAN Myosin-2 (sprot)

A myosin-2 that is encoded in the genome of human.


name: FAK1_RAT Focal adhesion kinase 1 (sprot)

description: A focal adhesion kinase 1 that is encoded in the genome of rat.


name: AKT1_RAT RAC-alpha serine/threonine-protein kinase (sprot)

description: A RAC-alpha serine/threonine-protein kinase that is encoded in the genome of rat.


name: S15A1_RABIT Solute carrier family 15 member 1 (sprot)


RXFP1_HUMAN Relaxin receptor 1 (sprot)

A relaxin receptor 1 that is encoded in the genome of human.


name: CH60_HUMAN 60 kDa heat shock protein, mitochondrial (sprot)

description: A 60 kDa heat shock protein, mitochondrial that is encoded in the genome of human.


name: THTR_HUMAN Thiosulfate sulfurtransferase (sprot)

description: A thiosulfate sulfurtransferase that is encoded in the genome of human.


name: HMMR_HUMAN Hyaluronan mediated motility receptor (sprot)

description: A hyaluronan mediated motility receptor that is encoded in the genome of human.


name: TRPC1_HUMAN Short transient receptor potential channel 1 (sprot)

description: A short transient receptor potential channel 1 that is encoded in the genome of human.


name: STIM1_HUMAN Stromal interaction molecule 1 (sprot)

description: A stromal interaction molecule 1 that is encoded in the genome of human.


name: FAAH2_HUMAN Fatty-acid amide hydrolase 2 (sprot)

description: A fatty-acid amide hydrolase 2 that is encoded in the genome of human.


GINSENOSIDE RB2

A ginsenoside found in Panax ginseng that is dammarane which is substituted by hydroxy groups at the 3beta, 12beta and 20 pro-S positions, in which the hydroxy groups at positions 3 and 20 have been converted to the corresponding beta-D-glucopyranosyl-(1->2)-beta-D-glucopyranoside and alpha-L-arabinopyranosyl-(1->6)-beta-D-glucopyranoside respectively, and in which a double bond has been introduced at the 24-25 position.


GINSENOSIDE RD

A ginsenoside found in Panax ginseng and Panax japonicus var. major that is (20S)-ginsenoside Rg3 in which the hydroxy group at position 20 has been converted to its beta-D-glucopyranoside.


GINSENOSIDE RB1

A ginsenoside found in Panax ginseng and Panax japonicus var. major that is ginsenoside Rd in which the beta-D-glucopyranoside group at position 20 is replaced by a beta-D-glucopyranosyl-beta-D-glucopyranoside group.


name: LAT_MYCTU Probable L-lysine-epsilon aminotransferase (sprot)


HPSE_MOUSE Heparanase (sprot)

A heparanase that is encoded in the genome of mouse.


name: Pyrrolidine-1,2-dicarboxylic acid 2-cyclopentylamide 1-phenylamide


name: PF-06456384 trihydrochloride, >=98% (HPLC)


name: 2-Butenoic acid, 4-[[(2S)-1-oxo-3-phenyl-2-[[(phenylmethoxy)carbonyl]amino]propyl]amino]-, ethyl ester, (2E)-


A secondary carboxamide resulting from the formal condensation of the carboxy group of {4-[1-(trifluoromethyl)cyclopropyl]phenyl}acetic acid with the amino group of 6-[(3-amino-1H-pyrazol-1-yl)methyl]pyridine-3-carbonitrile. It is a selective, orally available T-type calcium channel blocker that is being studied as a potential new treatment in epilepsy.


name: CAC1G_RAT Voltage-dependent T-type calcium channel subunit alpha-1G (sprot)

description: A voltage-dependent T-type calcium channel subunit alpha-1G that is encoded in the genome of rat.


name: CAC1I_RAT Voltage-dependent T-type calcium channel subunit alpha-1I (sprot)

description: A voltage-dependent T-type calcium channel subunit alpha-1I that is encoded in the genome of rat.


name: CAC1H_MOUSE Voltage-dependent T-type calcium channel subunit alpha-1H (sprot)

description: A voltage-dependent T-type calcium channel subunit alpha-1H that is encoded in the genome of mouse.


clofarabine

A purine nucleoside analogue consisting of a 6-amino-2-chloropurin-9-yl group attached to the 1beta position of 2'-deoxy-2'-fluoro-D-arabinofuranose. It is metabolized intracellularly to the active 5'-triphosphate metabolite, which inhibits DNA synthesisis and so stops the growth of cancer cells. Clofarabine is used as an antimetabolite antineoplastic agent in the treatment of relapsed or refractory acute lymphoblastic leukaemia.


name: 5NT3B_HUMAN 7-methylguanosine phosphate-specific 5'-nucleotidase (sprot)

description: A 7-methylguanosine phosphate-specific 5'-nucleotidase that is encoded in the genome of human.


name: PRFA_LISMO Listeriolysin regulatory protein (sprot)


name: KCC2D_RAT Calcium/calmodulin-dependent protein kinase type II subunit delta (sprot)

description: A calcium/calmodulin-dependent protein kinase type II subunit delta that is encoded in the genome of rat.


name: KCC2B_RAT Calcium/calmodulin-dependent protein kinase type II subunit beta (sprot)

description: A calcium/calmodulin-dependent protein kinase type II subunit beta that is encoded in the genome of rat.


name: KCC2G_RAT Calcium/calmodulin-dependent protein kinase type II subunit gamma (sprot)

description: A calcium/calmodulin-dependent protein kinase type II subunit gamma that is encoded in the genome of rat.


name: 3-{6-[(2-Chlorophenyl)methoxy)-2H-spiro[1-benzofuran-3,4'-piperidine]-1'-yl}propanoic acid trifluoroacetic acid


CRY2_HUMAN Cryptochrome-2 (sprot)

A cryptochrome-2 that is encoded in the genome of human.


SHRPN_HUMAN Sharpin (sprot)

A sharpin that is encoded in the genome of human.


A pyrazolone that is 5-methyl-4-methylene-2-(p-carboxyphenyl)-2,4-dihydro-3H-pyrazol-3-one in which the exocyclic carbon of the methylene group is attached to a 5-(4,5-dimethyl-2-nitrophenyl)furan-2-yl group by a single bond. C646 is a potent, cell permeable and selective competitive inhibitor of p300 and CBP (p300/CBP) histone acetyltransferases.


NEDD8_HUMAN NEDD8 (sprot)

A NEDD8 protein that is encoded in the genome of human.


name: EHD1_HUMAN EH domain-containing protein 1 (sprot)

description: An EH domain-containing protein 1 that is encoded in the genome of human.


ITB3_RAT Integrin beta-3 (sprot)

An integrin beta-3 that is encoded in the genome of rat.


name: PHOQ_SALTY Virulence sensor histidine kinase PhoQ (sprot)


name: CHEA_ECOLI Chemotaxis protein CheA (sprot)

description: A chemotaxis protein CheA that is encoded in the genome of Escherichia coli K-12.


name: PHOR_ECOLI Phosphate regulon sensor protein PhoR (sprot)

description: A phosphate regulon sensor protein PhoR that is encoded in the genome of Escherichia coli K-12.


name: WALK_STAEQ Sensor protein kinase WalK (sprot)


A member of the class of pyrazoles that is 1H-pyrazole carrying 1,4-benzodioxane-6-yl and 5-ethyl-2,4-dihydroxyphenyl substituents at positions 4 and 5 respectively.


COCHINCHINONE A

A member of the class of xanthones that is 9H-xanthen-9-one substituted by hydroxy groups at positions 1, 3 and 7, a prenyl group at position 2 and a geranyl group at position 4. Isolated from Cratoxylum cochinchinense, it exhibits cytotoxic and antioxidant activities.


name: WAAC_ECOLI Lipopolysaccharide heptosyltransferase 1 (sprot)

description: A lipopolysaccharide heptosyltransferase 1 that is encoded in the genome of Escherichia coli K-12.


α-MDG

An alpha-D-glucopyranoside having a methyl substituent at the anomeric position.


methyl beta-D-glucopyranoside

A beta-D-glucopyranoside having a methyl substituent at the anomeric position.


name: NR1H2_MOUSE Oxysterols receptor LXR-beta (sprot)

description: An oxysterols receptor LXR-beta that is encoded in the genome of mouse.


name: KAP2_HUMAN cAMP-dependent protein kinase type II-alpha regulatory subunit (sprot)

description: A cAMP-dependent protein kinase type II-alpha regulatory subunit that is encoded in the genome of human.


name: RNPA_STAAU Ribonuclease P protein component (sprot)


name: IMDH_MYCTU Inosine-5'-monophosphate dehydrogenase (sprot)


P2Y14_RAT P2Y purinoceptor 14 (sprot)

A P2Y purinoceptor 14 that is encoded in the genome of rat.


name: RGS17_HUMAN Regulator of G-protein signaling 17 (sprot)

description: A regulator of G-protein signaling 17 that is encoded in the genome of human.


A benzenetriol that is phloroglucinol in which two of the ring hydrogens are replaced by acetyl groups.


name: KCNA3_RAT Potassium voltage-gated channel subfamily A member 3 (sprot)

description: A voltage-gated potassium channel subunit KCNA3 that is encoded in the genome of rat.


name: KCNA4_RAT Potassium voltage-gated channel subfamily A member 4 (sprot)

description: A voltage-gated potassium channel alpha subunit KCNA4 that is encoded in the genome of rat.


name: KCNA6_RAT Potassium voltage-gated channel subfamily A member 6 (sprot)

description: A voltage-gated potassium channel subunit KCNA6 that is encoded in the genome of rat.


name: MED15_CANGA Mediator of RNA polymerase II transcription subunit 15 (sprot)


name: PDE4D_MOUSE 3',5'-cyclic-AMP phosphodiesterase 4D (sprot)

description: A 3',5'-cyclic-AMP phosphodiesterase 4D that is encoded in the genome of mouse.


pralatrexate

A pteridine that is the N-4-[1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl]benzoyl derivative of L-glutamic acid. Used for treatment of Peripheral T-Cell Lymphoma, an aggressive form of non-Hodgkins lymphoma.


name: GBRD_RAT Gamma-aminobutyric acid receptor subunit delta (sprot)

description: A gamma-aminobutyric acid receptor subunit delta that is encoded in the genome of rat.


An N-{5-[2-{4-[2-(dimethylamino)ethoxy]phenyl}-4-(pyridin-4-yl)-1H-imidazol-5-yl]-2,3-dihydro-1H-inden-1-ylidene}hydroxylamine in which the oxime group has E configuration.


name: CRYAB_HUMAN Alpha-crystallin B chain (sprot)

description: An alpha-crystallin B chain that is encoded in the genome of human.


lanosterol

A tetracyclic triterpenoid that is lanosta-8,24-diene substituted by a beta-hydroxy group at the 3beta position. It is the compound from which all steroids are derived.


name: DXR_PLAF7 1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic (sprot)


WIN 18446

A carboxamide that is 1,8-diaminooctane in which a hydrogen attached to each of the amino groups has been replaced by a dichloroacetyl group. Inhibitor of aldehyde dehydrogenase 1a2 (ALDH1a2). Inhibits the biosynthesis of retinoic acid from retinol in neonatal and adult murine testis. It down-regulates sex related genes in zebrafish.


name: VMAT2_MOUSE Synaptic vesicular amine transporter (sprot)

description: A synaptic vesicular amine transporter that is encoded in the genome of mouse.


A qinazoline derivative carrying chloro and fluoro substituents at positions 6 and 8 respectively, a 2-fluoro-6-hydroxyphenyl group at position 7, and a 4-(prop-2-enoyl)piperazin-1-yl group at position 4. A potent, selective, and orally bioavailable covalent KRAS-G12C inhibitor, it inhibits the protein coding gene KRAS (Kirsten rat sarcoma virus) with high potency in cells and animals.


ENL_HUMAN Protein ENL (sprot)

A protein ENL that is encoded in the genome of human.


AF9_HUMAN Protein AF-9 (sprot)

A protein AF-9 that is encoded in the genome of human.


name: IL23R_HUMAN Interleukin-23 receptor (sprot)

description: An interleukin-23 receptor that is encoded in the genome of human.


name: AOX_TRYBB Alternative oxidase, mitochondrial (sprot)


ASCOFURANONE

A dihydroxybenzaldehyde that is 2,4-dihydroxybenzaldehyde which is substituted by a (2E,6E)-7-[(2S)-5,5-dimethyl-4-oxotetrahydrofuran-2-yl]-3-methylocta-2,6-dien-1-yl group at position 3, chlorine at position 5, and a methyl group at position 6. A meroterpenoid produced by the soil fungus, Acremonium sclerotigenum. It is a promising drug candidate against the tropical disease, African trypanosomiasis.


name: GLRB_HUMAN Glycine receptor subunit beta (sprot)

description: A glycine receptor subunit beta that is encoded in the genome of human.


linalool

A monoterpenoid that is octa-1,6-diene substituted by methyl groups at positions 3 and 7 and a hydroxy group at position 3. It has been isolated from plants like Ocimum canum.


name: GLRA1_MOUSE Glycine receptor subunit alpha-1 (sprot)

description: A glycine receptor subunit alpha-1 that is encoded in the genome of mouse.


name: GLRA3_MOUSE Glycine receptor subunit alpha-3 (sprot)

description: A glycine receptor subunit alpha-3 that is encoded in the genome of mouse.


name: CDK8_MOUSE Cyclin-dependent kinase 8 (sprot)

description: A cyclin-dependent kinase 8 that is encoded in the genome of mouse.


PYRAZOFURIN

A C-glycosyl compound that is 4-hydroxy-1H-pyrazole-5-carboxamide in which the hydrogen at position 3 has been replaced by a beta-D-ribofuranosyl group.


RCOR3_HUMAN REST corepressor 3 (sprot)

A REST corepressor 3 that is encoded in the genome of human.


name: MACD2_HUMAN ADP-ribose glycohydrolase MACROD2 (sprot)

description: An ADP-ribose glycohydrolase MACROD2 that is encoded in the genome of human.


name: MACD1_HUMAN ADP-ribose glycohydrolase MACROD1 (sprot)

description: An ADP-ribose glycohydrolase MACROD1 that is encoded in the genome of human.


ALIZARIN RED

A dihydroxyanthraquinone that is 1,2-dihydroxyanthraquinone compound carrying an additional sulfo substituent at the 3-position. The monosodium salt is the biological stain 'alizarin red S'.


name: UBC12_HUMAN NEDD8-conjugating enzyme Ubc12 (sprot)

description: A NEDD8-conjugating enzyme Ubc12 that is encoded in the genome of human.


TLR2_MOUSE Toll-like receptor 2 (sprot)

A Toll-like receptor 2 that is encoded in the genome of mouse.


NNC 55-0396 dihydrochloride

The dihydrochloride salt of NNC 55-0396. It is a stable analogue of mibefradil and a highly selective T-type calcium channel blocker.


name: CAC1F_HUMAN Voltage-dependent L-type calcium channel subunit alpha-1F (sprot)

description: A voltage-dependent L-type calcium channel subunit alpha-1F that is encoded in the genome of human.


myriocin

An amino acid-based antibiotic derived from certain thermophilic fungi; acts as a potent inhibitor of serine palmitoyltransferase, the first step in sphingosine biosynthesis. Myriocin also possesses immunosuppressant activity.


3,4-dichlorobenzoic acid

A chlorobenzoic acid carrying chloro substituents at positions 3 and 4.


CFAD_RAT Complement factor D (sprot)

A complement factor D that is encoded in the genome of rat.


name: CO9_HUMAN Complement component C9 (sprot)

description: A complement component C9 that is encoded in the genome of human.


CO2_HUMAN Complement C2 (sprot)

A complement C2 that is encoded in the genome of human.


name: 2-(3-Biphenyl-4-YL-2-ethanesulfonylamino-propionylamino)-pentanedioic acid 5-amide 1-(4-carbamimidoyl-benzylamide)


ERIOCITRIN

A disaccharide derivative that consists of eriodictyol substituted by a 6-O-(alpha-L-rhamnopyranosyl)-beta-D-glucopyranosyl moiety at position 7 via a glycosidic linkage.


name: GBRB1_HUMAN Gamma-aminobutyric acid receptor subunit beta-1 (sprot)

description: A gamma-aminobutyric acid receptor subunit beta-1 that is encoded in the genome of human.


name: AATC_HUMAN Aspartate aminotransferase, cytoplasmic (sprot)

description: An aspartate aminotransferase, cytoplasmic that is encoded in the genome of human.


metiazinic acid

Phenothiazine substituted at nitrogen by a methyl group and at C-2 by a carboxymethyl group.


name: HAOX1_MOUSE 2-Hydroxyacid oxidase 1 (sprot)

description: A 2-hydroxyacid oxidase 1 that is encoded in the genome of mouse.


name: REV1_HUMAN DNA repair protein REV1 (sprot)

description: A DNA repair protein REV1 that is encoded in the genome of human.


D-histidine

An optically active form of histidine having D-configuration.


D-methionine

An optically active form of methionine having D-configuration.


N(tele)-methyl-L-histidine

A L-histidine derivative in which the methyl group is at N(tele)-position.


D-tryptophan

The D-enantiomer of tryptophan.


D-tyrosine

An optically active form of tyrosine having D-configuration.


D-phenylalanine

The D-enantiomer of phenylalanine.


alpha-methyl-L-phenylalanine

An L-phenylalanine derivative that consists of L-phenylalanine bearing an additional methyl substituent at position 2.


L-valine

The L-enantiomer of valine.


D-LEUCINE

The D-enantiomer of leucine.


L-m-tyrosine

A hydroxyphenylalanine that is L-phenylalanine with a substituent hydroxy group at position 3.


name: CCR7_HUMAN C-C chemokine receptor type 7 (sprot)

description: A C-C chemokine receptor type 7 that is encoded in the genome of human.


name: Prostaglandin D synthase (hematopoietic-type) inhibitor F092


name: JAK3_RAT Tyrosine-protein kinase JAK3 (sprot)

description: A tyrosine-protein kinase JAK3 that is encoded in the genome of rat.


name: 6,11-dioxo-12-naphtho[2,3-b]indolizinecarboxylic acid ethyl ester


An N-acylethanolamine 20:5 that is the ethanolamide of (5Z,8Z,11Z,14Z17Z)-eicosapentaenoic acid.


An N-acylethanolamine 22:6 that is the ethanolamide of (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoic acid.


erucamide

A primary fatty amide resulting from the formal condensation of the carboxy group of erucic acid with ammonia. It is commonly used as a slip additive in the plastic manufacturing industry.


palmitoleoyl ethanolamide

An N-acylethanolamine 16:1 that is the ethanolamide of palmitoleic acid.


A trimethoxyflavone that is myricetin in which the hydroxy groups at position 3, 4' and 5' have been replaced by methoxy groups. It has been isolated from Combretum quadrangulare.


A tetramethoxyflavone that is  myricetin in which the hydroxy groups at positions 3, 7, 4' and 5' have been replaced by methoxy groups. It has been isolated from Combretum quadrangulare.


name: PTPRZ_HUMAN Receptor-type tyrosine-protein phosphatase zeta (sprot)

description: A receptor-type tyrosine-protein phosphatase zeta that is encoded in the genome of human.


A phospho-N-acetylmuramoyl-pentapeptide-transferase that is encoded in the genome of Mycobacterium tuberculosis H37Rv.


name: 3 inverted exclamation marka-O-Demethyl-4 inverted exclamation marka-N-demethyl-4 inverted exclamation marka-N-acetyl-4 inverted exclamation marka-epi-staurosporine


name: NOTC1_MOUSE Neurogenic locus notch homolog protein 1 (sprot)

description: A neurogenic locus notch homolog protein 1 that is encoded in the genome of mouse.


oleandrin

A steroid saponin that consists of oleandrigenin having a 2,6-dideoxy-3-O-methyl-alpha-L-arabino-hexopyranosyl residue attached to the oxygen function at position 3.


A HETE having a (12S)-hydroxy group and (5Z)-, (8Z)-, (10E)- and (14Z)-double bonds.


A triazolopyrimidine that consists of 3,6-dihydro-7H-[1,2,3]triazolo[4,5-d]pyrimidine bearing amino and oxo substituents at positions 5 and 7 respectively.


name: ADHX_MOUSE Alcohol dehydrogenase class-3 (sprot)

description: An alcohol dehydrogenase class-3 that is encoded in the genome of mouse.


name: ADHX_RAT Alcohol dehydrogenase class-3 (sprot)

description: An alcohol dehydrogenase class-3 that is encoded in the genome of rat.


An organoiodine compound that is acrylic acid in which the vinylic hydrogens at positions 2 and 3 are replaced by mercapto and 4-iodophenyl groups respectively (the Z geoisomer).


(E)-hexadec-2-enoic acid

A hexadecenoic acid having a trans-double bond at the 2-position.


trans-2-icosenoic acid

An icosenoic acid in which the double bond is at the 2-3 position and has E configuration.


trans-octadec-2-enoic acid

An octadec-2-enoic acid having a trans- double bond.


ARACHIDIC ACID

A C20 striaght-chain saturated fatty acid which forms a minor constituent of peanut (L. arachis) and corn oils. Used as an organic thin film in the production of liquid crystals for a wide variety of technical applications.


N-acetyl-D-mannosamine

An N-acetylmannosamine having D-configuration.


name: HCD2_MOUSE 3-hydroxyacyl-CoA dehydrogenase type-2 (sprot)

description: A 3-hydroxyacyl-CoA dehydrogenase type-2 that is encoded in the genome of mouse.


name: PGAB_ECOLI Poly-beta-1,6-N-acetyl-D-glucosamine N-deacetylase (sprot)

description: A poly-beta-1,6-N-acetyl-D-glucosamine N-deacetylase that is encoded in the genome of Escherichia coli K-12.


name: NPY4R_MOUSE Neuropeptide Y receptor type 4 (sprot)

description: A neuropeptide Y receptor type 4 that is encoded in the genome of mouse.


name: AL1A2_CHICK Retinal dehydrogenase 2 (sprot)

description: A retinal dehydrogenase 2 that is encoded in the genome of chicken.


name: AL1A1_CHICK Aldehyde dehydrogenase 1A1 (sprot)

description: An aldehyde dehydrogenase 1A1 that is encoded in the genome of chicken.


name: COAX_BACAN Type III pantothenate kinase (sprot)


name: MPC2_HUMAN Mitochondrial pyruvate carrier 2 (sprot)

description: A brain protein 44 that is encoded in the genome of human.


name: TPX2_HUMAN Targeting protein for Xklp2 (sprot)

description: A targeting protein for Xklp2 that is encoded in the genome of human.


tetrodotoxin

A quinazoline alkaloid that is a marine toxin isolated from fish such as puffer fish. It has been shown to exhibit potential neutotoxicity due to its ability to block voltage-gated sodium channels.


name: AS3MT_HUMAN Arsenite methyltransferase (sprot)

description: An arsenite methyltransferase that is encoded in the genome of human.


name: TPA_MOUSE Tissue-type plasminogen activator (sprot)

description: A tissue-type plasminogen activator that is encoded in the genome of mouse.


name: HGPRT_MYCTU Hypoxanthine-guanine phosphoribosyltransferase (sprot)


name: 3-furancarboxylic acid, tetrahydro-4-methylene-5-oxo-2-propyl-, (2r,3s)-rel-


SURA_ECOLI Chaperone SurA (sprot)

A chaperone SurA that is encoded in the genome of Escherichia coli K-12.


name: IMDH_CRYNJ Inosine-5'-monophosphate dehydrogenase (sprot)


alpha-D-mannose

D-Mannopyranose having alpha-configuration at the anomeric centre.


name: SAES_STAA8 Histidine protein kinase SaeS (sprot)

description: A protein that is a translation product of the saeS gene in Staphylococcus aureus subsp. aureus NCTC 8325.


name: 3 inverted exclamation marka-Omethyl-5 inverted exclamation marka-hydroxydiplacone


name: PAK1_MOUSE Serine/threonine-protein kinase PAK 1 (sprot)

description: A serine/threonine-protein kinase PAK 1 that is encoded in the genome of mouse.


SEPANTRONIUM BROMIDE

An organic bromide salt consisting of sepantronium cations and bromide anions. It has been found to selectively inhibit survivin (BIRC5) gene promoter activity and to down-regulate survivin in vitro, so leading to induction of apoptosis.


name: UBE2B_HUMAN Ubiquitin-conjugating enzyme E2 B (sprot)

description: A ubiquitin-conjugating enzyme E2 B that is encoded in the genome of human.


name: WALK_STAAU Sensor protein kinase WalK (Fragment) (sprot)


An N-acyl-D-homoserine lactone having 3-oxododecanoyl as the acyl substituent.


A member of the class of pyrrolidin-2-ones that is pyrrolidin-2-one in which a hydrogen at the 3 pro-S position is replaced by a 3-oxododecanamido group.


PHB2_MOUSE Prohibitin-2 (sprot)

A prohibitin-2 that is encoded in the genome of mouse.


name: GNA11_HUMAN Guanine nucleotide-binding protein subunit alpha-11 (sprot)

description: A guanine nucleotide-binding protein subunit alpha-11 that is encoded in the genome of human.


name: PPA5_PIG Tartrate-resistant acid phosphatase type 5 (sprot)


LEP_ECOLI Signal peptidase I (sprot)

A signal peptidase I that is encoded in the genome of Escherichia coli K-12.


name: PGCA_BOVIN Aggrecan core protein (sprot)


NRAM_I63A3 Neuraminidase (sprot)

A neuraminidase subtype N8 (Influenza A virus) that is encoded in the genome of the H3N8 strain strain A/Duck/Ukraine/1/1963.


name: MCES_HUMAN mRNA cap guanine-N7 methyltransferase (sprot)

description: An mRNA cap guanine-N7 methyltransferase that is encoded in the genome of human.


name: Butanoic acid, 3-((2-naphthalenylsulfonyl)amino)-4-oxo-4-((2-phenylethyl)amino)-, (S)-


Catechol substituted at position 3 with a pentadecyl group.


3-phosphoglyceric acid

A monophosphoglyceric acid having the phospho group at the 3-position. It is an intermediate in metabolic pathways like glycolysis and calvin cycle.


METHYSERGIDE

A synthetic ergot alkaloid, structurally related to the oxytocic agent methylergonovine and to the potent hallucinogen LSD and used prophylactically to reduce the frequency and intensity of severe vascular headaches.


name: ESR1_SHEEP Estrogen receptor (Fragment) (sprot)


name: ESR2_SHEEP Estrogen receptor beta (sprot)


PANCURONIUM BROMIDE

A bromide salt consisting of two bromide ions and one pancuronium dication.


name: PLA1A_RAT Phospholipase A1 member A (sprot)

description: A phospholipase A1 member A that is encoded in the genome of rat.


name: (Z)-but-2-enedioic acid;[(Z)-(8-methyl-1-oxa-8-azaspiro[4.5]decan-3-ylidene)amino] acetate;oxalic acid


name: (Z)-but-2-enedioic acid;[(Z)-(8-methyl-1-oxa-8-azaspiro[4.5]decan-3-ylidene)amino] propanoate;oxalic acid


name: (Z)-but-2-enedioic acid;[(E)-(8-methyl-1-oxa-8-azaspiro[4.5]decan-3-ylidene)amino] benzoate;oxalic acid


dilevalol

A 2-hydroxy-5-{1-hydroxy-2-[(4-phenylbutan-2-yl)amino]ethyl}benzamide that has 1R,2R-configuration.


CASB_RAT Beta-casein (sprot)

A beta-casein that is encoded in the genome of rat.


name: SL9A1_RABIT Sodium/hydrogen exchanger 1 (sprot)

description: A protein that is a translation product of the SLC9A1 gene in rabbit.


name: SL9A3_RABIT Sodium/hydrogen exchanger 3 (sprot)

description: A protein that is a translation product of the SLC9A3 gene in rabbit.


A 3-hydroxy steroid that is 17beta-estradiol substituted by a 11-[butyl(methyl)amino]-11-oxoundecyl group at position 7R. It is a steroidal antioestrogen that inhibits the cell proliferation of breast-carcinoma cell lines.


name: Raloxifene Bismethyl Ether (hydrochloride)


name: Carbamic acid, ((1-((2-(diethylamino)ethyl)amino)-9-oxo-9H-thioxanthen-4-yl)methyl)-, methyl ester


name: ITPR2_HUMAN Inositol 1,4,5-trisphosphate receptor type 2 (sprot)

description: An inositol 1,4,5-trisphosphate receptor type 2 that is encoded in the genome of human.


imidacloprid-urea

A imidazolidinone that is imidazolidin-2-one substituted by a (6-chloropyridin-3-yl)methyl group at position 1. It is a metabolite of the insecticide imidacloprid.


oxcarbazepine

A dibenzoazepine derivative, having a carbamoyl group at the ring nitrogen, substituted with an oxo group at C-4 of the azepeine ring which is also hydrogenated at C-4 and C-5. It is a anticholinergic anticonvulsant and mood stabilizing drug, used primarily in the treatment of epilepsy.


eslicarbazepine acetate

The acetate ester, with S configuration, of licarbazepine. An anticonvulsant, it is approved for use in Europe and the United States as an adjunctive therapy for epilepsy.


name: N-alpha-(2-Naphthylsulfonyl)-N(3-amidino-L-phenylalaninyl)isopipecolinic acid methyl ester


name: CBG_HUMAN Corticosteroid-binding globulin (sprot)

description: A corticosteroid-binding globulin that is encoded in the genome of human.


name: PDK1_RAT [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial (sprot)

description: A [pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial that is encoded in the genome of rat.


name: PDK4_RAT [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial (sprot)

description: A [pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial that is encoded in the genome of rat.


name: Benzilic Acid 1-Ethyl-3-pyrrolidinyl Ester


name: [(2R,3S,4R,5R)-3,4-dihydroxy-5-purin-9-yloxolan-2-yl]methyl phosphono hydrogen phosphate


6-phospho-D-gluconic acid

A gluconic acid phosphate having the phosphate group at the 6-position. It is an intermediate in the pentose phosphate pathway.


polyvinyl alcohol

A homopolymer macromolecule obtained by polymerisation of vinyl alcohol.


A thiosugar that is beta-D-glucopyranose in which the hydroxy group at position 1 is replaced by a sulfanyl group


name: D-glycero-D-ido-Heptonic acid, 2,6-anhydro-, 2-methylhydrazide


name: Octanedioic acid hydroxyamide pyridin-4-ylamide


name: Octanedioic acid hydroxyamide pyridin-2-ylamide


name: ABCC9_RAT ATP-binding cassette sub-family C member 9 (sprot)

description: An ATP-binding cassette sub-family C member 9 that is encoded in the genome of rat.


name: PDE4D_RAT 3',5'-cyclic-AMP phosphodiesterase 4D (sprot)

description: A 3',5'-cyclic-AMP phosphodiesterase 4D that is encoded in the genome of rat.


pasireotide

A six-membered homodetic cyclic peptide composed from L-phenylglycyl, D-tryptophyl, L-lysyl, O-benzyl-L-tyrosyl, L-phenylalanyl and modified L-hydroxyproline residues joined in sequence. A somatostatin analogue with pharmacologic properties mimicking those of the natural hormone somatostatin; used (as its diaspartate salt) for treatment of Cushing's disease.


name: SUV3_HUMAN ATP-dependent RNA helicase SUPV3L1, mitochondrial (sprot)

description: An ATP-dependent RNA helicase SUPV3L1, mitochondrial that is encoded in the genome of human.


HYDROXYPREGNENOLONE

A 17alpha-hydroxy steroid that is 3alpha-hydroxy-5beta-pregnan-20-one carrying an additional hydroxy group at position 17alpha.


algestone

A C21-steroid that is pregn-4-ene substituted by oxo groups at position 3 and 20 and hydroxy groups at positions 16 and 17.


ANDROSTANEDIOL

An androstane-3,17-diol that is 5alpha-androstane substituted by beta-hydroxy groups at positions 3 and 17. It is a metabolite of dihydrotestosterone.


A hydroxychrysene that is chrysene in which the hydrogen at position 3 has been replaced by a hydroxy group. It is a metabolite of the polycyclic aromatic hydrocarbon chrysene.


KEPONE

An  organochlorine compound with insecticidal activity.


name: PARC_STAAM DNA topoisomerase 4 subunit A (sprot)


name: Thioacetic acid S-[(5-phenylcarbamoyl-pentylcarbamoyl)-methyl] ester


name: [(2R,3S,4R,5R)-3,4-dihydroxy-5-[6-(naphthalen-1-ylamino)purin-9-yl]oxolan-2-yl]methyl phosphono hydrogen phosphate


fleroxacin

A fluoroquinolone antibiotic that is 4-oxo-1,4-dihydroquinoline which is substituted at positions 1, 3, 6, 7 and 8 by 2-fluoroethyl, carboxy, fluoro, 4-methylpiperazin-1-yl and fluoro groups, respectively. It is active against many Gram-positive and Gram-negative bacteria.


name: 4-(3-Chlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylic acid mono (3,3-diphenylpropyl) ester


name: Carbamimidothioic acid, 2-[(aminoiminomethyl)amino]ethyl ester, dihydrobromide (9CI)


name: Thieno(3,2-b)quinolin-8(4H)-one, 9-(3-bromo-4-fluorophenyl)-2,3,5,6,7,9-hexahydro-, 1,1-dioxide, (9S)-


name: ISPA_ECOLI Farnesyl diphosphate synthase (sprot)

description: A farnesyl diphosphate synthase that is encoded in the genome of Escherichia coli K-12.


gentamicin

Any of a group of aminoglycoside antibiotics produced by fermentation of some Micromonospora spp.


HINOKIFLAVONE

A biflavonoid that is apigenin substituted by a 4-(5,7-dihydroxy-4-oxo-4H-chromen-2-yl)phenoxy group at position 6. A diflavonyl ether, it is isolated from Rhus succedanea and has been found to possess significant cytotoxic potential.


ANIASATIN

A sesquiterpene lactone with formula C15H20O8. It is a neurotoxic natural product found in plants of the family Illiciaceae.


DIPHENYLACETYLENE

An  arylacetylene that is acetylene in which the hydrogens are replaced by phenyl groups.


flibanserin

An N-alkylpiperazine that is 1-[2-(1,3-dihydro-2-oxobenzimidazol-1-yl)ethyl]piperazine in which the remaining amino proton is replaced by a 3-(trifluoromethyl)phenyl group. A multifunctional serotonin agonist and antagonist which is used for the treatment of pre-menopausal women with hypoactive sexual desire disorder.


name: G6PT1_HUMAN Glucose-6-phosphate exchanger SLC37A4 (sprot)

description: A glucose-6-phosphate exchanger SLC37A4 that is encoded in the genome of human.


name: phenyl-carbamic acid (S)-1-(5-methyl-6-oxo-6,7-dihydro-5H-dibenzo[b,d]azepin-7-ylcarbamoyl)-ethyl ester


name: 2-[4-(3,4-Dimethoxy-benzene sulfonyl)-piperazin-1-yl]-thiazole-5-carboxylic acid hydroxyamide


name: 2-[4-(4-Trifluoromethoxy-benzene sulfonyl)-piperazin-1-yl]-thiazole-5-carboxylic acid hydroxyamide


name: GLT_PYRHO Glutamate transporter homolog (sprot)


DAPT

A dipeptide consisting of alanylphenylglycine derivatised as a 3,5-difluorophenylacetamide at the amino terminal and a tert-butyl ester at the carboxy terminal. It is a gamma-secretase inhibitor.


MANASSANTIN B

A lignan isolated from Saururus cernuus and Saururus chinensis and has been shown to exhibit antineoplastic activity.


cytochalasin B

An organic heterotricyclic compound, that is a mycotoxin which is cell permeable an an inhibitor of cytoplasmic division by blocking the formation of contractile microfilaments.


LITSEAEFOLOSIDE C

An O-acyl carbohydrate consisting of glucose attached to 2-hydroxy-4-vanilloyloxymethylphenyl and trans-caffeoyl group at positions 1 and 6 respectively. Isolated from stems of Ilex latifolia, it exhibits inhibitory activity against alpha-glucosidase and lipase.


SKULLCAPFLAVONE II

A tetramethoxyflavone that is flavone substituted by methoxy groups at positions 6, 7, 8 and 6' and hydroxy groups at positons 5 and 2' respectively.


A dihydroxybenzaldehyde carrying hydroxy groups at positions 2 and 5.


name: CAC1F_MOUSE Voltage-dependent L-type calcium channel subunit alpha-1F (sprot)

description: A voltage-dependent L-type calcium channel subunit alpha-1F that is encoded in the genome of mouse.


Z-PICEID

A stilbenoid that is cis-resveratrol substituted at position 3 by a beta-D-glucosyl residue.


CALLYSPONGINOL SULFATE A

An organic sodium salt which is the monosodium salt of callysponginol sulfonic acid A. It is isolated from the marine sponge Callyspongia truncata as a membrane type 1 matrix metalloproteinase (MT1-MMP) inhibitor.


ITACONATE

A dicarboxylic acid that is methacrylic acid in which one of the methyl hydrogens is substituted by a carboxylic acid group.


name: MMP9_BOVIN Matrix metalloproteinase-9 (sprot)

description: A matrix metalloproteinase-9 that is encoded in the genome of cow.


NYMPHAEOL B

A tetrahydroxyflavanone that is (2S)-flavanone substituted by hydroxy group at positions 5, 7, 3' and 4' and a geranyl group at position 2'. Isolated from Macaranga tanarius and propolis collected in Okinawa, it exhibits radical scavenging activity.


KLUGINE

An isoquinoline alkaloid that is emetan substituted by methoxy groups at positions 7' and 11 and hydroxy groups at positions 1', 6' and 10'. Isolated from Psychotria klugii, it exhibits antileishmanial and antiplasmodial activities.


tetracycline

A broad-spectrum polyketide antibiotic produced by the Streptomyces genus of actinobacteria.


CRYPTOPLEURINE

An organic heteropentacyclic compound that is (14aR)-11,12,13,14,14a,15-hexahydro-9H-dibenzo[f,h]pyrido[1,2-b]isoquinoline substituted at positions 2, 3 and 6 by methoxy groups.


TOP1_YEAST DNA topoisomerase 1 (sprot)

A protein that is a translation product of the TOP1 gene in yeast.


RHAMNOCITRIN

A monomethoxyflavone that is the 7-methyl ether derivative of  kaempferol.


LIQUIRITIN

A flavanone glycoside that is  liquiritigenin attached to a beta-D-glucopyranosyl residue at position 4' via a glycosidic linkage.


name: AGTRA_MOUSE Type-1 angiotensin II receptor A (sprot)

description: An angiotensin II receptor 1A that is encoded in the genome of mouse.


BENZYL CINNAMATE

The cinnamate ester derived from cinnamic acid and benzyl alcohol. Occuring in Balsam of Peru and Tolu balsam, in Sumatra and Penang benzoin, and as the main constituent of copaiba balsam, it is used in heavy oriental perfumes, as a fixative and as a flavouring agent.


dihydrochalcone

A member of the class of dihydrochalcones that is acetophenone in which one of the hydrogens of the methyl group is replaced by a benzyl group.


KEMPOPEPTIN A

A 19-membered cyclodepsipeptide isolated from Floridian marine cyanobacterium Lyngbya sp. It exhibits inhibitory activity towards the enzymes elastase and chymotrypsin.


ALTERNARIOL

A benzochromenone that is 6H-benzo[c]chromen-6-one which is substituted by a methyl group at position 1 and by hydroxy groups at positions 3, 7, and 9. It is the most important mycotoxin produced by the black mould Alternaria species, which are the most common mycoflora infecting small grain cereals worldwide.


name: 6-Ethyl-4-hydroxyquinoline-3-carboxylic acid ethyl ester


name: PRP19_YEAST Pre-mRNA-processing factor 19 (sprot)

description: A protein that is a translation product of the PRP19 gene in yeast.


NP-313 is a specific small molecule inhibitor of ubiquitin-like protein UHRF1, binds with the SRA domain groove of UHRF1.


name: FABF_STAAU 3-oxoacyl-[acyl-carrier-protein] synthase 2 (Fragment) (sprot)


CONVALLATOXIN

A cardenolide glycoside that consists of strophanthidin having a 6-deoxy-alpha-L-mannopyranosyl (L-rhamnosyl) group attached at position 3.


name: DEVR_MYCTU DNA-binding transcriptional activator DevR/DosR (sprot)

description: A protein that is a translation product of the devR gene in Mycobacterium tuberculosis H37Rv.


CATA_RAT Catalase (sprot)

A catalase that is encoded in the genome of rat.


phenylbutyrate

A monocarboxylic acid the structure of which is that of butyric acid substituted with a phenyl group at C-4.  It is a histone deacetylase inhibitor that displays anticancer activity. It inhibits cell proliferation, invasion and migration and induces apoptosis in glioma cells. It also inhibits protein isoprenylation, depletes plasma glutamine, increases production of foetal haemoglobin through transcriptional activation of the gamma-globin gene and affects hPPARgamma activation.


name: 12-(4-Chloro-benzenesulfonyl)-4,5,12-triaza-tricyclo[6.3.1.02,6]dodeca-2(6),3-diene-10-carboxylic acid ethyl ester


garenoxacin

A quinolinemonocarboxylic acid that is 1,4-dihydroquinoline-3-carboxylic acid that is substituted by a cyclopropyl group at position 1, an oxo group at position 4, a (1R)-1-methyl-2,3-dihydro-1H-isoindol-5-yl group at position 7, and a difluoromethoxy group at position 8.


name: MPI_YEAST Mannose-6-phosphate isomerase (sprot)

description: A mannose-6-phosphate isomerase that is encoded in the genome of yeast.


name: MANA_ECOLI Mannose-6-phosphate isomerase (sprot)

description: A mannose-6-phosphate isomerase that is encoded in the genome of Escherichia coli K-12.


name: LEU3_THET8 3-isopropylmalate dehydrogenase (sprot)


name: TTPA_HUMAN Alpha-tocopherol transfer protein (sprot)

description: An alpha-tocopherol transfer protein that is encoded in the genome of human.


name: CEPT1_HUMAN Choline/ethanolaminephosphotransferase 1 (sprot)

description: A choline/ethanolaminephosphotransferase 1 that is encoded in the genome of human.


name: RHOC_HUMAN Rho-related GTP-binding protein RhoC (sprot)

description: A Rho-related GTP-binding protein RhoC that is encoded in the genome of human.


name: CISD1_RAT CDGSH iron-sulfur domain-containing protein 1 (sprot)

description: A CDGSH iron-sulfur domain-containing protein 1 that is encoded in the genome of rat.


POLG_DEN2P Genome polyprotein (sprot)

A dengue virus genome polyprotein that is encoded in the genome of Dengue virus 2 Puerto Rico/PR159-S1/1969.


name: CACB1_HUMAN Voltage-dependent L-type calcium channel subunit beta-1 (sprot)

description: A voltage-dependent L-type calcium channel subunit beta-1 that is encoded in the genome of human.


name: DAPAT_ARATH LL-diaminopimelate aminotransferase, chloroplastic (sprot)

description: A protein that is a translation product of the DAP gene in Arabidopsis thaliana.


DIAZEPINOMICIN

A dibenzodiazepine with a farnesyl sidechain synthesized by Micromonospora sp.. It has a potent activity against a broad spectrum of tumor cell lines.


name: PGTB1_RAT Geranylgeranyl transferase type-1 subunit beta (sprot)

description: A geranylgeranyl transferase type-1 subunit beta that is encoded in the genome of rat.


A gallate ester obtained by the formal condensation of gallic acid with the hydroxy group at position 7 of 3',4',5',5,7-pentahydroxyflavan. Isolated from the leaves of Pithecellobium clypearia, it exhibits antiviral activity.


name: 4'-CYCLOPROPYL-5'-(5-(TRIFLUORO METHYL)PYRIDIN-2-YL SULFONYL)-4',5'-DIHYDROSPIRO[CYCLOPROPANE-1,6'-PYRAZOLO[4,3-C]PYRIDIN]-7'(1'H)-ONE (ENANTIOMERIC MIX)


name: 4'-CYCLO PROPYL-5'-(6-(TRIFLUORO METHYL)PYRIDIN-3-YL SULFONYL)-4',5'-DIHYDROSPIRO[CYCLOPROPANE-1,6'-PYRAZOLO[4,3-C]PYRIDIN]-7'(1'H)-ONE (ENANTIOMERIC MIX)


BLUMENOL A

A (6S)-vomifoliol with a R configuration for the hydroxy group at position 9.


name: H2S-releasing peptide conjugate building block ADT


name: KCNKA_RAT Potassium channel subfamily K member 10 (sprot)

description: A potassium channel subfamily K member 10 that is encoded in the genome of rat.


M2_I000F Matrix protein 2 (sprot)

An influenzavirus matrix protein 2 that is encoded in the genome of the H7N7 strain A/Chicken/Weybridge.


name: CD69_HUMAN Early activation antigen CD69 (sprot)

description: A CD69 molecule that is encoded in the genome of human.


name: KLRBA_RAT Killer cell lectin-like receptor subfamily B member 1A (sprot)

description: A protein that is a translation product of the Klrb1a gene in rat.


N-ACETYLMANNOSAMINE

An N-acetylmannosamine having pyranose form and alpha-D-configuration.


N-Acetylglucosamine

An N-acetyl-D-glucosamine having beta-configuration at the anomeric centre.


CEPHALOTAXINE

A benzazepine alkaloid isolated from Cephalotaxus harringtonia.


name: ERF3_YEAST Eukaryotic peptide chain release factor GTP-binding subunit (sprot)

description: A protein that is a translation product of the SUP35 gene in yeast.


name: LOLA_ECOLI Outer-membrane lipoprotein carrier protein (sprot)

description: An outer-membrane lipoprotein carrier protein that is encoded in the genome of Escherichia coli K-12.


CYC_HUMAN Cytochrome c (sprot)

A cytochrome c, somatic that is encoded in the genome of human.


name: PAPD_ECOLX Chaperone protein PapD (sprot)


name: DIM5_NEUCR Histone-lysine N-methyltransferase, H3 lysine-9 specific dim-5 (sprot)


name: MTH_DROME G-protein coupled receptor Mth (sprot)

description: A protein that is a translation product of the mth gene in fruit fly.


DIHYDROFOLIC ACID

A folic acid derivative acted upon by dihydrofolate reductase to produce tetrahydrofolic acid. It interacts with bacteria during cell division and is targeted by various drugs to prevent nucleic acid synthesis.


name: FOLC_ECOLI Dihydrofolate synthase/folylpolyglutamate synthase (sprot)

description: A dihydrofolate synthase/folylpolyglutamate synthase that is encoded in the genome of Escherichia coli K-12.


name: GAP1_YEAST General amino-acid permease GAP1 (sprot)

description: A protein that is a translation product of the GAP1 gene in yeast.


A dipeptide composed of L-leucine and L-methioninamide units joined by a peptide linkage. It is a noncompetitive inhibitor of Gap1 transport.


etamivan

Phenol substituted at C-2 and C-4 by a methoxy group and an N,N-diethylaminocarbonyl group respectively. A respiratory stimulant drug related to nikethamide, it has now fallen largely into disuse.


ceftaroline fosamil

A cephalosporin having [4-(1-methylpyridinium-4-yl)-1,3-thiazol-2-yl]sulfanyl and {(2Z)-2-(ethoxyimino)-2-[5-(phosphonoamino)-1,2,4-thiadiazol-3-yl]acetyl}amino side groups located at positions 3 and 7 respectively. The N-phospho prodrug of ceftaroline, a broad-spectrum antibiotic active against methicillin-resistant Staphylococcus aureus (MRSA). It is used for the treatment of adults with acute bacterial skin and skin structure infections.


name: PBPA_STRPN Penicillin-binding protein 1A (sprot)

description: A protein that is a translation product of the ponA gene in Streptococcus pneumoniae TIGR4.


name: PBP2_STRPN Penicillin-binding protein 2B (sprot)

description: A peptidoglycan D,D-transpeptidase MrdA that is encoded in the genome of Streptococcus pneumoniae TIGR4.


cefotaxime

A cephalosporin compound having acetoxymethyl and [2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino side groups.


A member of the class of chalcones that is 3',5'-dimethylchalcone substituted by hydroxy groups at positions 2, 2' and 4' and a methoxy group at position 6'. Isolated from Psorothamnus polydenius, it exhibits antiparasitic activity.


A member of the class of  chalcones that is trans-chalcone substituted by hydroxy groups at positions 4, 2' and 4', a methoxy group at position 6' and methyl groups at positions 3' and 5'. Isolated from the buds of Cleistocalyx operculatus, it has been shown to exhibit inhibitory effects on the viral neuraminidases from two influenza viral strains, H1N1 and H9N2.


A member of the class of chalcones that is trans-chalcone substituted by a methyl group at position 3', hydroxy groups at positions 2' and 4' and a methoxy group at position 6'. Isolated from the buds of Cleistocalyx operculatus, it has been shown to exhibit inhibitory effects on the viral neuraminidases from two influenza viral strains, H1N1 and H9N2.


A monohydroxyflavanone that is (2S)-flavanone substituted by a hydroxy group at position 5, a methoxy group at position 7, a methyl group at position 8 and a formyl group at position 6. Isolated from the buds of Cleistocalyx operculatus, it has been shown to exhibit inhibitory effects on the viral neuraminidases from two influenza viral strains, H1N1 and H9N2.


A dihydroxyflavanon that is (2S)-flavanone substituted by hydroxy groups at positions 2 and 7, a methoxy group at position 5 and methyl groups at positions 6 and 8. Isolated from the buds of Cleistocalyx operculatus, it has been shown to exhibit inhibitory effects on the viral neuraminidases from two influenza viral strains, H1N1 and H9N2.


A monohydroxyflavanone that is (2S)-flavanone substituted by a hydroxy group at position 5, a methoxy group at position 7, a methyl group at position 6 and a formyl group at position 8. Isolated from Cleistocalyx operculatus, it has been shown to exhibit inhibitory effects on the viral neuraminidases from two influenza viral strains, H1N1 and H9N2.


A methoxyisoflavone that is isoflavone substituted by a methoxy group at position 5, a hydroxy group at position 7 and methyl groups at positions 6 and 8. It has been isolated from the buds of Cleistocalyx operculatus and has been shown to exhibit inhibitory effects on the viral neuraminidases from two influenza viral strains,H1N1 and H9N2.


A member of the class of chalcones that is trans-chalcone substituted by hydroxy groups at positions 2' and 4', a methoxy group at position 6' and methyl groups at positions 3' and 5'. Isolated from the buds of Cleistocalyx operculatus, it has been shown to exhibit inhibitory effects on the viral neuraminidases from two influenza viral strains, H1N1 and H9N2.


A monohydroxyflavone that is flavone substituted by a hydroxy group at position 7, a methoxy group at position 5 and methyl groups at positions 6 and 8. Isolated from the buds of Cleistocalyx operculatus, it has been shown to exhibit inhibitory effects on the viral neuraminidases from two influenza viral strains, H1N1 and H9N2.


name: 1H-indole-3-carboxylic acid 1-(3-carboxy-propyl)-piperidin-4-ylmethyl ester


name: Octanedioic acid adamantan-1-ylamide hydroxyamide


A hydrazone that is hydrazonomalononitrile in which one of the hydrazine hydrogens is substituted by a p-trifluoromethoxyphenyl group.


imipenem

A broad-spectrum, intravenous beta-lactam antibiotic of the carbapenem subgroup.


name: CD36_HUMAN Platelet glycoprotein 4 (sprot)

description: A platelet glycoprotein 4 that is encoded in the genome of human.


An  imidazolidinone that is parabanic acid substituted by a 2-phenylethyl group at position 1.


name: 4-Thiazolidinecarboxylic acid, 2-(2-furanyl)-, (4R)-


A carboxylic ester obtained by the formal condensation of the secondary hydroxy group of 4-hydroxy-6-[hydroxy(phenyl)methyl]pyridin-2(1H)-one with 3-methylbutanoic acid. It is isolated from the culture broth of Penicillium sp. SPF-32629 and acts as an inhibitor of the enzyme chymase (EC 3.4.21.39).


A carboxylic ester obtained by the formal condensation of the benzylic hydroxy group of 4-hydroxy-6-[hydroxy(phenyl)methyl]-2-oxo-1,2-dihydropyridine-3-carboxylic acid with 3-methylbutanoic acid. It is isolated from the culture broth of Penicillium sp. SPF-32629 and acts as an inhibitor of the enzyme chymase (EC 3.4.21.39).


name: 3-(3,4-Dimethoxy-phenyl)-3-(3,5-dimethoxy-phenyl)-acrylic acid methyl ester


florbetapir

An aromatic ether consisting of a pyridine ring substituted at position 2 by a 2-{2-[2-((18)F)fluoroethoxy]ethoxy}ethoxy group and at position 5 and a 2-(4-methylaminophenyl)vinyl group. A positron emission tomography imaging ligand for the detection of amyloid aggregation associated with Alzheimer disease.


A member of the class of xanthones that is 9H-xanthene substituted by hydroxy groups at positions 1 and 7, a methoxy group at position 4 and an oxo group at position 9. It has been isolated from the stems of Cratoxylum cochinchinense.


florbetaben

A member of the class of stilbenoids in which the para-hydrogens of stilbene are replaced by methylamino and 2-{2-[2-((18)F)fluoroethoxy]ethoxy}ethoxy) groups. A positron emission tomography imaging ligand for the detection of amyloid aggregation associated with Alzheimer disease.


name: ANTR2_HUMAN Anthrax toxin receptor 2 (sprot)

description: An anthrax toxin receptor 2 that is encoded in the genome of human.


GLUTARATE

An alpha,omega-dicarboxylic acid that is a linear five-carbon dicarboxylic acid.


name: SO4C1_HUMAN Solute carrier organic anion transporter family member 4C1 (sprot)

description: A solute carrier organic anion transporter family member 4C1 that is encoded in the genome of human.


Gly-Gly-Phe

A tripeptide composed of glycine, glycine and L-phenylalanine residues joined in sequence.