name: SIR2_HUMAN NAD-dependent protein deacetylase sirtuin-2 (sprot)

description: An NAD-dependent protein deacetylase sirtuin-2 that is encoded in the genome of human.


anandamide

An N-acylethanolamine 20:4 resulting from the formal condensation of carboxy group of arachidonic acid with the amino group of ethanolamine.


N-oleoylethanolamide

An N-(long-chain-acyl)ethanolamine that is the ethanolamide of oleic acid. The monounsaturated analogue of the endocannabinoid anandamide.


GLR_HUMAN Glucagon receptor (sprot)

A glucagon receptor that is encoded in the genome of human.


name: GIPR_HUMAN Gastric inhibitory polypeptide receptor (sprot)

description: A gastric inhibitory polypeptide receptor that is encoded in the genome of human.


CHALCONE

The trans-isomer of chalcone.


name: NQO2_HUMAN Ribosyldihydronicotinamide dehydrogenase [quinone] (sprot)

description: A ribosyldihydronicotinamide dehydrogenase [quinone] that is encoded in the genome of human.


melatonin

A member of the class of  acetamides that is acetamide in which one of the hydrogens attached to the nitrogen atom is replaced by a 2-(5-methoxy-1H-indol-3-yl)ethyl group. It is a hormone secreted by the pineal gland in humans.


name: NOS2_HUMAN Nitric oxide synthase, inducible (sprot)

description: A nitric oxide synthase, inducible that is encoded in the genome of human.


name: NOS3_HUMAN Nitric oxide synthase 3 (sprot)

description: A nitric oxide synthase 3 that is encoded in the genome of human.


name: NOS1_HUMAN Nitric oxide synthase 1 (sprot)

description: A nitric oxide synthase 1 that is encoded in the genome of human.


name: MTCA1_MYCTU Beta-carbonic anhydrase 1 (sprot)

description: A protein that is a translation product of the mtcA1 gene in Mycobacterium tuberculosis H37Rv.


saccharin

A 1,2-benzisothiazole having a keto-group at the 3-position and two oxo substituents at the 1-position. It is used as an artificial sweetening agent.


A member of the class of thiadiazoles that is 1,3,4-thiadiazol-2-amine which is substituted by a (5-nitro-1,3-thiazol-2-yl)sulfanediyl group at position 5. It is a c-Jun N-terminal kinase inhibitor (IC50 = 0.7uM) and exhibits antibacterial properties.


name: CP51_TRYCC Sterol 14-alpha demethylase (sprot)

description: A protein that is a translation product of any of the 2 copies of the CYP51 gene in Trypanosoma cruzi strain CL Brener.


melagatran

A member of the class of azetidines that is (2S)-azetidine 2-carboxylic acid in which the carboxylic acid has been converted to the amide corresponding to formal condensation with 4-(aminomethyl)benzenecarboximidamide and in which the hydrogen attached to the azetidine nitrogen is replaced by a (2R)-2-cyclohexyl-2-[(carboxymethyl)amino]acetyl group.


name: Tacrine-dihydropyridine hybrid (tacripyrine), 1


name: Tacrine-dihydropyridine hybrid (tacripyrine), 2


name: Tacrine-dihydropyridine hybrid (tacripyrine), 3


name: Tacrine-dihydropyridine hybrid (tacripyrine), 4


name: Tacrine-dihydropyridine hybrid (tacripyrine), 5


name: Tacrine-dihydropyridine hybrid (tacripyrine), 6


name: Tacrine-dihydropyridine hybrid (tacripyrine), 7


name: Tacrine-dihydropyridine hybrid (tacripyrine), 8


name: Tacrine-dihydropyridine hybrid (tacripyrine), 9


name: Tacrine-dihydropyridine hybrid (tacripyrine), 10


name: Tacrine-dihydropyridine hybrid (tacripyrine), 11


name: Tacrine-dihydropyridine hybrid (tacripyrine), 12


name: Tacrine-dihydropyridine hybrid (tacripyrine), 13


name: Tacrine-dihydropyridine hybrid (tacripyrine), 14


A primary amino compound that is the 5-hydroxy derivative of tryptamine.


name: 5HT4R_HUMAN 5-hydroxytryptamine receptor 4 (sprot)

description: A 5-hydroxytryptamine receptor 4 that is encoded in the genome of human.


curcumin

A beta-diketone that is methane in which two of the hydrogens are substituted by feruloyl groups. A natural dyestuff found in the root of Curcuma longa.


name: ADA1B_RAT Alpha-1B adrenergic receptor (sprot)

description: An alpha-1B adrenergic receptor that is encoded in the genome of rat.


bisphenol A

A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.


N-acetylserotonin

An N-acylserotonin resulting from the formal condensation of the primary amino group of serotonin with the carboxy group of acetic acid.


name: RUNX1_HUMAN Runt-related transcription factor 1 (sprot)

description: A runt-related transcription factor 1 that is encoded in the genome of human.


name: 2-benzoylimino-1-(2-furanylmethyl)-10-methyl-5-oxo-3-dipyrido[3,4-c:1',2'-f]pyrimidinecarboxylic acid ethyl ester


name: Hydroxyethylene tripeptide inhibitor, 2a


name: N-methyl-alanine tripeptide inhibitor, 2b


fluoxetine

A racemate comprising equimolar amounts of (R)- and (S)-fluoxetine. A selective serotonin reuptake inhibitor (SSRI), it is used (generally as the hydrochloride salt) for the treatment of depression (and the depressive phase of bipolar disorder), bullimia nervosa, and obsessive-compulsive disorder.


name: alpha-Sulfone piperidine hydroxamate, 11a


name: alpha-Sulfone piperidine hydroxamate, 1a


name: alpha-Sulfone piperidine hydroxamate, 11b


name: alpha-Sulfone piperidine hydroxamate, 11c


name: alpha-Sulfone piperidine hydroxamate, 1b


name: alpha-Sulfone piperidine hydroxamate, 11d


name: alpha-Sulfone piperidine hydroxamate, 11e


name: alpha-Sulfone piperidine hydroxamate, 1c


name: alpha-Sulfone piperidine hydroxamate, 11f


name: alpha-Sulfone piperidine hydroxamate, 11g


name: alpha-Sulfone piperidine hydroxamate, 1d


name: alpha-Sulfone piperidine hydroxamate, 11h


name: alpha-Sulfone piperidine hydroxamate, 11i


name: alpha-Sulfone piperidine hydroxamate, 11j


name: alpha-Sulfone piperidine hydroxamate, 11k


name: alpha-Sulfone piperidine hydroxamate, 11l


name: alpha-Sulfone piperidine hydroxamate, 1e


name: alpha-Sulfone piperidine hydroxamate, 11m


name: alpha-Sulfone piperidine hydroxamate, 11n


name: MCHR1_HUMAN Melanin-concentrating hormone receptor 1 (sprot)

description: A melanin-concentrating hormone receptor 1 that is encoded in the genome of human.


name: MAPK2_HUMAN MAP kinase-activated protein kinase 2 (sprot)

description: A MAP kinase-activated protein kinase 2 that is encoded in the genome of human.


name: MAPK3_HUMAN MAP kinase-activated protein kinase 3 (sprot)

description: A MAP kinase-activated protein kinase 3 that is encoded in the genome of human.


name: MAPK5_HUMAN MAP kinase-activated protein kinase 5 (sprot)

description: A MAP kinase-activated protein kinase 5 that is encoded in the genome of human.


name: MKNK1_HUMAN MAP kinase-interacting serine/threonine-protein kinase 1 (sprot)

description: A MAP kinase-interacting serine/threonine-protein kinase 1 that is encoded in the genome of human.


name: KS6A4_HUMAN Ribosomal protein S6 kinase alpha-4 (sprot)

description: A ribosomal protein S6 kinase alpha-4 that is encoded in the genome of human.


name: [{2-[5-(3,4-Dimethoxy-phenyl)-[1,3,4]oxadiazol-2-ylsulfanyl]-acetyl}-(4-fluoro-phenyl)-amino]-acetic acid ethyl ester


name: Furan-2-carboxylic acid cyclopentylcarbamoyl-(2-fluoro-phenyl)-methyl ester


name: 1-[2-(Cyclopropylamino)-2-keto-ethyl]nipecotic acid ethyl ester;oxalic acid


name: (5,6-Dimethyl-4-oxo-4H-thieno[2,3-d]pyrimidin-3-yl)-acetic acid 1-tert-butylcarbamoyl-ethyl ester


ERGOCRISTINE

Ergotaman bearing benzyl, hydroxy, and isopropyl groups at the 5', 12' and 2' positions, respectively, and oxo groups at positions 3', 6', and 18. It is a natural ergot alkaloid.


metergoline

An ergoline alkaloid that is the N-benzyloxycarbonyl derivative of lysergamine. A 5-HT2 antagonist. Also 5-HT1 antagonist and 5-HT1D ligand. Has moderate affinity for 5-HT6 and high affinity for 5-HT7.


DIHYDROERGOCRISTINE MESYLATE

The methanesulfonic acid salt of dihydroergocristine. It has been used as the for the symptomatic treatment of mental deterioration associated with cerebrovascular insufficiency and in peripheral vascular disease. It is also a component of ergoloid mesylate (codergocrine mesilate), a mixture of ergot alkaloid derivatives that is used as a vasodilator and has shown mild benefits in the treatment of vascular dementia.


A tryptamine alkaloid that is N,N-dimethyltryptamine substituted by a methoxy group at position 5.


ERGOCORNINE

Ergotaman bearing a hydroxy group at the 12' position, isopropyl groups at the 2' and 5'alpha positions, and oxo groups at positions 3', 6', and 18. It is a natural ergot alkaloid.


oxymetazoline

A member of the class of phenols that is 2,4-dimethylphenol which is substituted at positions 3 and 6 by 4,5-dihydro-1H-imidazol-2-ylmethyl and tert-butyl groups, respectively. A direct-acting sympathomimetic with marked alpha-adrenergic activity, it is a vasoconstrictor that is used (generally as the hydrochloride salt) to relieve nasal congestion.


name: 4-chlorobenzoic acid 2-(2-amino-3-cyano-1-pyrrolo[3,2-b]quinoxalinyl)ethyl ester


name: 6-Amino-8-(4-butoxy-3-methoxyphenyl)-5,7,7-tricyano-1,3,8,8a-tetrahydroisoquinoline-2-carboxylic acid ethyl ester


name: 7-(4-Fluorophenyl)-2,5-dimethyl-1,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxylic acid 2-methoxyethyl ester


phentolamine

A substituted aniline that is 3-aminophenol in which the hydrogens of the amino group are replaced by 4-methylphenyl and 4,5-dihydro-1H-imidazol-2-ylmethyl groups respectively. An alpha-adrenergic antagonist, it is used for the treatment of hypertension.


fenbendazole

A member of the class of benzimidazoles that is 1H-benzimidazole  which is substituted at positons 2 and 5 by (methoxycarbonyl)amino and phenylsulfanediyl groups, respectively. A broad-spectrum anthelmintic, it is used, particularly in veterinary medicine, for the treatment of nematodal infections.


name: ALK_HUMAN ALK tyrosine kinase receptor (sprot)

description: An ALK tyrosine kinase receptor that is encoded in the genome of human.


OXDA_HUMAN D-amino-acid oxidase (sprot)

A D-amino-acid oxidase that is encoded in the genome of human.


OXDD_HUMAN D-aspartate oxidase (sprot)

A D-aspartate oxidase that is encoded in the genome of human.


OXDA_RAT D-amino-acid oxidase (sprot)

A D-amino-acid oxidase that is encoded in the genome of rat.


An azaspiro compound resulting from the formal fusion of position 3 of 6-chloro-oxindole with position 3 of (2R,3SS5S)-3-(3-chloro-2-fluorophenyl)-5-(2,2-dimethylpropyl)-N-[2-(morpholin-4-yl)ethyl]pyrrolidine-2-carboxamide. It is a potent inhibitor of the MDM2-p53 interaction.


name: UFO_HUMAN Tyrosine-protein kinase receptor UFO (sprot)

description: A tyrosine-protein kinase receptor UFO that is encoded in the genome of human.


name: BMPR2_HUMAN Bone morphogenetic protein receptor type-2 (sprot)

description: A BMP receptor type-2 that is encoded in the genome of human.


name: CD11B_HUMAN Cyclin-dependent kinase 11B (sprot)

description: A cyclin-dependent kinase 11B that is encoded in the genome of human.


name: CD11A_HUMAN Cyclin-dependent kinase 11A (sprot)

description: A cyclin-dependent kinase 11A that is encoded in the genome of human.


name: CDK19_HUMAN Cyclin-dependent kinase 19 (sprot)

description: A cyclin-dependent kinase 19 that is encoded in the genome of human.


A 2-methoxy-N-[3-[4-[3-methyl-4-[(6-methyl-3-pyridinyl)oxy]anilino]-6-quinazolinyl]prop-2-enyl]acetamide in which the double bond adopts a trans-configuration. It is a potent inhibitor of HER2/ErbB2 (IC50 = 10 nM) and exhibits anti-cancer activity.


name: 5HT1E_HUMAN 5-hydroxytryptamine receptor 1E (sprot)

description: A 5-hydroxytryptamine receptor 1E that is encoded in the genome of human.


name: (S)-2-(4-Diisopropylcarbamoyl-2-isopropoxy-benzoylamino)-4-methyl-pentanoic acid methyl ester


name: Naphthalene and Benzamide Derivative, 21


name: Naphthalene and Benzamide Derivative, 23


A benzamide that is GRL-0617 in which one of the hydrogen's of the primary amino group is replaced by an acetyl group. It an inhibitor of SARS-CoV and SARS-CoV-2 papain-like protease (PLpro) with an IC50 of 2.6 muM and 5.0 muM, respectively. It also inhibits SARS-CoV and SARS-CoV-2 infection of Vero E6 cells in vitro (EC50 values are 13.1 and 21 muM, respectively).


A benzamide resulting from the formal condensation of the carboxy group of 5-amino-2-methylbenzoic acid with the amino group of (1R)-1-(naphthalen-1-yl)ethan-1-amine. It is a potent noncovalent inhibitor (IC50 = 600 nM) of severe acute respiratory syndrome-coronavirus papain-like protease (SARS-CoV PLpro).


name: M3K1_HUMAN Mitogen-activated protein kinase kinase kinase 1 (sprot)

description: A mitogen-activated protein kinase kinase kinase 1 that is encoded in the genome of human.


HMOX1_RAT Heme oxygenase 1 (sprot)

A heme oxygenase 1 that is encoded in the genome of rat.


HMOX2_RAT Heme oxygenase 2 (sprot)

A heme oxygenase 2 that is encoded in the genome of rat.


CP2E1_RAT Cytochrome P450 2E1 (sprot)

A cytochrome P450 2E1 that is encoded in the genome of rat.


CP3A1_RAT Cytochrome P450 3A1 (sprot)

A protein that is a translation product of the Cyp3a1 gene in rat.


name: V9GZ37_HUMAN Heat shock 70 kDa protein 1A (trembl)


hexachlorophene

An organochlorine compound that is diphenylmethane in which each of the phenyl groups is substituted by chlorines at positions 2, 3, and 5, and by a hydroxy group at position 6. An antiseptic that is effective against Gram-positive organisms, it is used in soaps and creams for the treatment of various skin disorders. It is also used in agriculture as an acaricide and fungicide, but is not approved for such use within the European Union.


name: DUS6_RAT Dual specificity protein phosphatase 6 (sprot)

description: A dual specificity protein phosphatase 6 that is encoded in the genome of rat.


name: CDK7_HUMAN Cyclin-dependent kinase 7 (sprot)

description: A cyclin-dependent kinase 7 that is encoded in the genome of human.


name: CDK8_HUMAN Cyclin-dependent kinase 8 (sprot)

description: A cyclin-dependent kinase 8 that is encoded in the genome of human.


name: CDK9_HUMAN Cyclin-dependent kinase 9 (sprot)

description: A cyclin-dependent kinase 9 that is encoded in the genome of human.


name: CLK1_HUMAN Dual specificity protein kinase CLK1 (sprot)

description: A dual specificity protein kinase CLK1 that is encoded in the genome of human.


name: CLK4_HUMAN Dual specificity protein kinase CLK4 (sprot)

description: A dual specificity protein kinase CLK4 that is encoded in the genome of human.


levoketoconazole

A cis-1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine which dioxolane moiety has (2S,4R)-configuration.


A 1-(4-{[2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)-4-isopropylpiperazine in which positions 2 and 4 of the 1,3-dioxolane moiety have S and R configuration, respectively.


SULCONAZOLE

A member of the class of imidazoles that is 1-ethyl-1H-imidazole in which one of the hydrogens of the methyl group is replaced by a (4-chlorobenzyl)sulfanediyl group while a second is replaced by a 2,4-dichlorophenyl group.


ISOCONAZOLE

A member of the class of imidazoles that carries a 2-[(2,6-dichlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl group at position 1.


miconazole

A racemate composed of equimolar amounts of (R)- and (S)-miconazole. Used (as its nitrate salt) to treat skin infections such as athlete's foot, jock itch, ringworm and other fungal skin infections. It inhibits the synthesis of ergosterol, a critical component of fungal cell membranes.


econazole

A racemate composed of equimolar amounts of (R)- and (S)-econazole. Used (as its nitrate salt) to treat skin infections such as athlete's foot, jock itch, ringworm and other fungal skin infections.


clotrimazole

A member of the class of imidazoles that is 1H-imidazole in which the hydrogen attached to a nitrogen is replaced by a monochlorotrityl group.


name: MCL1_HUMAN Induced myeloid leukemia cell differentiation protein Mcl-1 (sprot)

description: An induced myeloid leukemia cell differentiation protein Mcl-1 that is encoded in the genome of human.


name: B2LA1_HUMAN Bcl-2-related protein A1 (sprot)

description: A Bcl-2-related protein A1 that is encoded in the genome of human.


name: SRC_CHICK Proto-oncogene tyrosine-protein kinase Src (sprot)

description: A proto-oncogene tyrosine-protein kinase Src that is encoded in the genome of chicken.


indole-3-propionic acid

An  indol-3-yl carboxylic acid that is  propionic acid substituted by a 1H-indol-3-yl group at position 3.


name: KAT1_HUMAN Kynurenine--oxoglutarate transaminase 1 (sprot)

description: A kynurenine--oxoglutarate transaminase 1 that is encoded in the genome of human.


3-(indol-3-yl)lactic acid

A hydroxy monocarboxylic acid that is lactic acid substituted by a 1H-indol-3-yl group at position 3. It is a metabolite of tryptophan.


name: RARG_HUMAN Retinoic acid receptor gamma (sprot)

description: A retinoic acid receptor gamma that is encoded in the genome of human.


tretinoin

A retinoic acid in which all four exocyclic double bonds have E- (trans-) geometry.


alitretinoin

A retinoic acid in which the exocyclic double bonds have 7E,9Z,11E,13E geometry.


name: RARA_HUMAN Retinoic acid receptor alpha (sprot)

description: A retinoic acid receptor alpha that is encoded in the genome of human.


name: RARB_HUMAN Retinoic acid receptor beta (sprot)

description: A retinoic acid receptor beta that is encoded in the genome of human.


name: ISPF_ECOLI 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase (sprot)

description: A 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase that is encoded in the genome of Escherichia coli K-12.


cyclic CMP

A 3',5'-cyclic pyrimidine nucleotide having cytosine as the nucleobase.


cidofovir

Cytosine substituted at the 1 position by a 3-hydroxy-2-(phosphonomethoxy)propyl group (S configuration). A nucleoside analogue, it is an injectable antiviral used for the treatment of cytomegalovirus (CMV) retinitis in AIDS patients.


name: 3-[5-(4-ethylphenyl)-2-tetrazolyl]propanoic acid methyl ester


name: Thiophene-2-carboxylic acid 1-[(thiophen-2-ylmethyl)-carbamoyl]-ethyl ester


name: 4-Amino-2-(1-oxo-1,2,3,4-tetrahydro-naphthalen-2-ylsulfanyl)-pyrimidine-5-carboxylic acid ethyl ester


daunorubicin

A natural product found in Actinomadura roseola.


nordihydroguiaretic acid

A tetrol that is butane which is substituted at positions 2 and 3 by 3,4-dihydroxybenzyl groups. Masoprocol, the meso-form found in the leaves of the creosote bush (Larrea divaricata), is a potent lipoxygenase inhibitor.


name: N-[2-[(phenylmethyl)amino]-1,3-benzodioxol-2-yl]carbamic acid ethyl ester


toxoflavin

A pyrimidotriazine that is 1,6-dimethyl-1,5,6,7-tetrahydropyrimido[5,4-e][1,2,4]triazine with oxo groups at positions 5 and 7.


chloroxine

A monohydroxyquinoline that is quinolin-8-ol in which the hydrogens at positions 5 and 7 have been substituted by chlorine. A synthetic antibacterial prepared by chlorination of quinolin-8-ol, it is used for the treatment of dandruff and seborrhoeic dermatitis of the scalp.


clioquinol

A monohydroxyquinoline that is quinolin-8-ol in which the hydrogens at positions 5 and 7 are replaced by chlorine and iodine, respectively. It has antibacterial and atifungal properties, and is used in creams for the treatment of skin infections. It has also been investigated as a chelator of copper and zinc ions for the possible treatment of Alzheimer's disease.


oxyquinoline

A monohydroxyquinoline that is quinoline substituted by a hydroxy group at position 8. Its fungicidal properties are used for the control of grey mould on vines and tomatoes.


An indolamine carrying an amino group at position 5.


A member of the class of hydroxyindoles that is 1H-indole in which the hydrogen at position 5 has been replaced by a hydroxy group.


quinoline yellow

A quinoline derivative with a 1,3-dioxoindan-2-yl substituent at C-2.


name: 4-(4-ethoxycarbonylanilino)-2-quinazolinecarboxylic acid ethyl ester


name: KPCD1_HUMAN Serine/threonine-protein kinase D1 (sprot)

description: A serine/threonine-protein kinase D1 that is encoded in the genome of human.


name: DDR1_HUMAN Epithelial discoidin domain-containing receptor 1 (sprot)

description: A discoidin domain-containing receptor 1 that is encoded in the genome of human.


name: DDR2_HUMAN Discoidin domain-containing receptor 2 (sprot)

description: A discoidin domain-containing receptor 2 that is encoded in the genome of human.


name: EPHA3_HUMAN Ephrin type-A receptor 3 (sprot)

description: An ephrin type-A receptor 3 that is encoded in the genome of human.


name: HS71A_HUMAN Heat shock 70 kDa protein 1A (sprot)

description: A heat shock 70 kDa protein 1A that is encoded in the genome of human.


ADP

A purine ribonucleoside 5'-diphosphate having adenine as the nucleobase.


adenosine

A ribonucleoside composed of a molecule of adenine attached to a ribofuranose moiety via a beta-N(9)-glycosidic bond.


name: ABCG2_HUMAN Broad substrate specificity ATP-binding cassette transporter ABCG2 (sprot)

description: A broad substrate specificity ATP-binding cassette transporter ABCG2 that is encoded in the genome of human.


Fumitremorgin C

An organic heteropentacyclic compound that is a mycotoxic indole alkaloid produced by several fungi. A potent and specific inhibitor of the breast cancer resistance protein multidrug transporter.


ACCC_ECOLI Biotin carboxylase (sprot)

A biotin carboxylase that is encoded in the genome of Escherichia coli K-12.


name: Furan-2-carboxylic acid 5-amino-1-(toluene-4-sulfonyl)-1H-pyrazol-3-yl ester


name: Furan-2-carboxylic acid 3-tetrazol-1-yl-phenyl ester


name: Isonicotinic acid 3-chloro-4-oxo-4H-chromen-7-yl ester


name: Furan-2-carboxylic acid 5-amino-1-(4-fluoro-benzenesulfonyl)-1H-pyrazol-3-yl ester


name: Furan-2-carboxylic acid 5-amino-1-(4-methoxy-benzenesulfonyl)-1H-pyrazol-3-yl ester


name: Furan-2-carboxylic acid 4-methoxycarbonyl-phenyl ester


name: 2-furancarboxylic acid (2-acetyl-1-benzothiophen-3-yl) ester


name: 4-Methyl-benzoic acid 2-furan-2-yl-4-[(E)-phenyliminomethyl]-oxazol-5-yl ester


name: Benzenesulfonic acid 1,3-dioxo-1,3-dihydro-isoindol-2-yl ester


name: Acetic acid 4-(2,3-dihydro-1H-perimidin-2-yl)-2-methoxy-phenyl ester


name: Propionic acid 2-[[7-(1,3-benzothiazol-2-ylthio)-4-nitro-benzofurazan-5-yl]amino]ethyl ester


name: Acetic acid 3-[[7-(1,3-benzothiazol-2-ylthio)-4-nitro-benzofurazan-5-yl]amino]propyl ester


name: [5-(4-Methoxy-benzylidene)-4-oxo-4,5-dihydro-thiazol-2-ylsulfanyl]-acetic acid ethyl ester


name: EPHA7_HUMAN Ephrin type-A receptor 7 (sprot)

description: An ephrin type-A receptor 7 that is encoded in the genome of human.


name: EPHB3_HUMAN Ephrin type-B receptor 3 (sprot)

description: An ephrin type-B receptor 3 that is encoded in the genome of human.


name: MK15_HUMAN Mitogen-activated protein kinase 15 (sprot)

description: A mitogen-activated protein kinase 15 that is encoded in the genome of human.


name: CHK2_HUMAN Serine/threonine-protein kinase Chk2 (sprot)

description: A serine/threonine-protein kinase Chk2 that is encoded in the genome of human.


POLG_DEN1S Genome polyprotein (sprot)

A dengue virus genome polyprotein that is encoded in the genome of Dengue virus 1 Singapore/S275/1990.


POLG_DEN2N Genome polyprotein (sprot)

A dengue virus genome polyprotein that is encoded in the genome of Dengue virus 2 Thailand/NGS-C/1944.


POLG_DEN3P Genome polyprotein (sprot)

A dengue virus genome polyprotein that is encoded in the genome of Dengue virus 3 Philippines/H87/1956.


POLG_DEN4P Genome polyprotein (sprot)

A dengue virus genome polyprotein that is encoded in the genome of Dengue virus 4 Philippines/H241/1956.


name: DPOA2_BOVIN DNA polymerase alpha subunit B (sprot)

description: A DNA polymerase alpha subunit B that is encoded in the genome of cow.


DPOLB_RAT DNA polymerase beta (sprot)

A DNA polymerase beta that is encoded in the genome of rat.


name: DYR_MOUSE Dihydrofolate reductase (sprot)

description: A dihydrofolate reductase that is encoded in the genome of mouse.


RNH1_HUMAN Ribonuclease H1 (sprot)

A ribonuclease H1 that is encoded in the genome of human.


name: Furan-2-carboxylic acid 4-oxo-1,2,3,4-tetrahydro-cyclopenta[c]chromen-7-yl ester


name: Furan-2-carboxylic acid 5-chloro-quinolin-8-yl ester


name: 3-(2-Methoxy-phenylcarbamoyl)-pyrazole-1-carboxylic acid butyl ester


name: 2-(3-chlorophenoxy)acetic acid [4-[(4-methylanilino)-oxomethyl]phenyl] ester


RNH_ECOLI Ribonuclease HI (sprot)

A ribonuclease HI that is encoded in the genome of Escherichia coli K-12.


sotrastaurin

A member of the class of maleimides that is maleimide which is substituted at position 3 by an indol-3-yl group and at position 4 by a quinazolin-4-yl group, which in turn is substituted at position 2 by a 4-methylpiperazin-1-yl group. It is a potent and selective inhibitor of protein kinase C and has been investigated as an immunosuppresant in renal transplant patients.


name: PIN1_HUMAN Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (sprot)

description: A peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 that is encoded in the genome of human.


name: CSK21_RAT Casein kinase II subunit alpha (sprot)

description: A casein kinase II subunit alpha that is encoded in the genome of rat.


HXK4_HUMAN Hexokinase-4 (sprot)

A hexokinase-4 that is encoded in the genome of human.


CAN_CANAL Carbonic anhydrase (sprot)

A protein that is a translation product of the NCE103 gene in Candida albicans SC5314.


name: AT2A1_RABIT Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 (sprot)


name: B2LA1_MOUSE Bcl-2-related protein A1 (sprot)

description: A protein that is a translation product of the Bcl2a1 gene in mouse.


name: 2-[[4-(4-fluorophenyl)-6-(trifluoromethyl)-2-pyrimidinyl]sulfonyl]acetic acid ethyl ester


name: 2-amino-7-cyclohexyl-6,8-dioxo-4,5,5a,8a-tetrahydrothieno[2,3-e]isoindole-3-carboxylic acid ethyl ester


name: 3-benzamido-5-bromo-2-benzofurancarboxylic acid methyl ester


name: 3,8-dimethyl-4-oxo-7,8,9,10-tetrahydro-6H-thieno[1,2]pyrimido[4,5-a]azepine-2-carboxylic acid ethyl ester


name: 4-amino-3-phenyl-2-sulfanylidene-5-thiazolecarboxylic acid methyl ester


name: MPI_HUMAN Mannose-6-phosphate isomerase (sprot)

description: A mannose-6-phosphate isomerase that is encoded in the genome of human.


esculetin

A  hydroxycoumarin that is umbelliferone in which the hydrogen at position 6 is substituted by a hydroxy group. It is used in filters for absorption of ultraviolet light.


ebselen

A benzoselenazole that is 1,2-benzoselenazol-3-one carrying an additional phenyl substituent at position 2. Acts as a mimic of glutathione peroxidase.


trinitrophenol

A C-nitro compound comprising phenol having three nitro substtituents at the 2-, 4- and 6-positions.


A 4-hydroxy steroid that consists of 17beta-estradiol having an additional hydroxy group at position 4.


name: Benzenesulfonic acid [(2,5-dimethyl-4-oxo-1-cyclohexa-2,5-dienylidene)amino] ester


myricitrin

A glycosyloxyflavone that consists of myricetin attached to a alpha-L-rhamnopyranosyl residue at position 3 via a glycosidic linkage. Isolated from Myrica cerifera, it exhibits anti-allergic activity.


name: Benzenesulfonic acid [(2-isopropyl-4-keto-5-methyl-cyclohexa-2,5-dien-1-ylidene)amino] ester


P2Y14_HUMAN P2Y purinoceptor 14 (sprot)

A P2Y purinoceptor 14 that is encoded in the genome of human.


name: PIM3_HUMAN Serine/threonine-protein kinase pim-3 (sprot)

description: A serine/threonine-protein kinase Pim-3 that is encoded in the genome of human.


MDM4_HUMAN Protein Mdm4 (sprot)

A protein Mdm4 that is encoded in the genome of human.


nisoxetine

A secondary amino compound that is N-methyl-3-phenylpropan-1-amine substituted at position 3 by a 2-methoxyphenoxy group.


desipramine

A dibenzoazepine consisting of 10,11-dihydro-5H-dibenzo[b,f]azepine substituted on nitrogen with a 3-(methylamino)propyl group.


name: 2-Oxo-1,2-dihydropyridin-3-yl amide derivative, 6b


name: 2-Oxo-1,2-dihydropyridin-3-yl amide derivative, 6t


name: 2-Oxo-1,2-dihydropyridin-3-yl amide derivative, 7b


name: 2-Oxo-1,2-dihydropyridin-3-yl amide derivative, 7t


name: 2-Oxo-1,2-dihydropyridin-3-yl amide derivative, 7v


name: 2-Oxo-1,2-dihydropyridin-3-yl amide derivative, 7w


name: 2-Oxo-1,2-dihydropyridin-3-yl amide derivative, 7x


name: 2-Oxo-1,2-dihydropyridin-3-yl amide derivative, 8t


name: 2-Oxo-1,2-dihydropyridin-3-yl amide derivative, 9t


name: indole-2-carboxamide derivative, 25e (S-isomer)


name: indole-2-carboxamide derivative, 25e (R-isomer)


name: DUS1_HUMAN Dual specificity protein phosphatase 1 (sprot)

description: A dual specificity protein phosphatase 1 that is encoded in the genome of human.


name: 4-Methyl-benzoic acid 5-amino-1-(4-methoxy-benzenesulfonyl)-1H-pyrazol-3-yl ester


name: Thiophene-2-carboxylic acid pyridin-2-yl-[(thiophen-2-ylmethyl)-carbamoyl]-methyl ester


name: benzoic acid [5-amino-1-(4-methoxyphenyl)sulfonyl-3-pyrazolyl] ester


name: acetic acid [3-oxo-2-(trifluoromethyl)-4H-1,4-benzoxazin-2-yl] ester


dicumarol

A hydroxycoumarin that is methane in which two hydrogens have each been substituted by a 4-hydroxycoumarin-3-yl group. Related to warfarin, it has been used as an anticoagulant.


name: NQO1_HUMAN NAD(P)H dehydrogenase [quinone] 1 (sprot)

description: An NAD(P)H dehydrogenase [quinone] 1 that is encoded in the genome of human.


name: Benzazepinelidene acetamide derivative, 1b


name: V2R_HUMAN Vasopressin V2 receptor (sprot)

description: A vasopressin V2 receptor that is encoded in the genome of human.


name: Benzazepinelidene acetamide derivative, 1c


name: Benzazepinelidene acetamide derivative, 1d


name: Benzazepinelidene acetamide derivative, 1e


name: Benzazepinelidene acetamide derivative, 1f


name: Benzazepinelidene acetamide derivative, 1g


name: V1AR_HUMAN Vasopressin V1a receptor (sprot)

description: A vasopressin V1a receptor that is encoded in the genome of human.


V2R_RAT Vasopressin V2 receptor (sprot)

A vasopressin V2 receptor that is encoded in the genome of rat.


tolvaptan

A member of the class of benzazepines that is 2,3,4,5-tetrahydro-1H-1-benzazepine substituted by 2-methyl-4-(2-methylbenzamido)benzoyl, hydroxy, and chloro groups at positions 1, 5, and 7, respectively.


name: AA2BR_HUMAN Adenosine receptor A2b (sprot)

description: An adenosine receptor A2b that is encoded in the genome of human.


name: PE2R1_MOUSE Prostaglandin E2 receptor EP1 subtype (sprot)

description: A prostaglandin E2 receptor EP1 subtype that is encoded in the genome of mouse.


name: PE2R2_MOUSE Prostaglandin E2 receptor EP2 subtype (sprot)

description: A prostaglandin E2 receptor EP2 subtype that is encoded in the genome of mouse.


name: PE2R4_MOUSE Prostaglandin E2 receptor EP4 subtype (sprot)

description: A prostaglandin E2 receptor EP4 subtype that is encoded in the genome of mouse.


name: PE2R3_MOUSE Prostaglandin E2 receptor EP3 subtype (sprot)

description: A prostaglandin E2 receptor EP3 subtype that is encoded in the genome of mouse.


tolfenamic acid

An aminobenzoic acid that is anthranilic acid in which one of the hydrogens attached to the nitrogen is replaced by a 3-chloro-2-methylphenyl group. Tolfenamic acid is used specifically for relieving the pain of migraine. It also shows anticancer activity.


CAH2_BOVIN Carbonic anhydrase 2 (sprot)

A vertebrate-type carbonic anhydrase 2 that is encoded in the genome of cow.


name: LOADL_BPT4 Sliding-clamp-loader large subunit (sprot)


name: DPO3X_ECOLI DNA polymerase III subunit tau (sprot)

description: A DNA polymerase III subunit tau that is encoded in the genome of Escherichia coli K-12.


CATB_RAT Cathepsin B (sprot)

A cathepsin B that is encoded in the genome of rat.


CATZ_RAT Cathepsin Z (sprot)

A cathepsin Z that is encoded in the genome of rat.


CATH_RAT Pro-cathepsin H (sprot)

A cathepsin H that is encoded in the genome of rat.


LGMN_MOUSE Legumain (sprot)

A legumain that is encoded in the genome of mouse.


CATB_MOUSE Cathepsin B (sprot)

A cathepsin B that is encoded in the genome of mouse.


CATL1_MOUSE Procathepsin L (sprot)

A murine-type cathepsin L that is encoded in the genome of mouse.


CASP3_MOUSE Caspase-3 (sprot)

A caspase-3 that is encoded in the genome of mouse.


Z-DEVD-FMK

A tetrapeptide consisting of Fmoc-L-aspartic acid 4-methyl ester, methyl L-alpha-glutamic acid 5-methyl ester, L-valine and the fluoromethyl ketone derived from the 1-carboxy group of L-aspartic acid 4-methyl ester coupled in sequence. It is a specific, irreversible caspase-3 inhibitor that also shows potent inhibition of caspase-6, caspase-7, caspase-8, and caspase-10.


name: CDPK1_PLAFK Calcium-dependent protein kinase 1 (sprot)


docetaxel

A tetracyclic diterpenoid that is paclitaxel with the N-benzyloxycarbonyl group replaced by N-tert-butoxycarbonyl, and the acetoxy group at position 10 replaced by a hydroxy group.


A pyrazolopyrimidine that is pyrazolo[1,5-a]pyrimidine bearing quinolin-4-yl and 4-isopropyloxyphenyl substituents at positions 3 and 6 respectively.


name: ACVR1_HUMAN Activin receptor type-1 (sprot)

description: An activin receptor type-1 that is encoded in the genome of human.


dorsomorphin

A pyrazolopyrimidine that is pyrazolo[1,5-a]pyrimidine which is substituted at positions 3 and 6 by pyridin-4-yl and p-[2-(piperidin-1-yl)ethoxy]phenyl groups, respectively. It is a potent, selective, reversible, and ATP-competitive inhibitor of AMPK (AMP-activated protein kinase, EC 2.7.11.31) and a selective inhibitor of bone morphogenetic protein (BMP) signaling.


name: CLK2_HUMAN Dual specificity protein kinase CLK2 (sprot)

description: A dual specificity protein kinase CLK2 that is encoded in the genome of human.


name: SF3B3_HUMAN Splicing factor 3B subunit 3 (sprot)

description: A splicing factor 3B subunit 3 that is encoded in the genome of human.


name: RIPK1_HUMAN Receptor-interacting serine/threonine-protein kinase 1 (sprot)

description: A receptor-interacting serine/threonine-protein kinase 1 that is encoded in the genome of human.


name: PK3CD_HUMAN Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (sprot)

description: A phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform that is encoded in the genome of human.


WNT2_MOUSE Protein Wnt-2 (sprot)

A protein Wnt-2 that is encoded in the genome of mouse.


PLD1_HUMAN Phospholipase D1 (sprot)

A phospholipase D1 that is encoded in the genome of human.


name: BLC1_ECOLX Beta-lactamase CTX-M-1 (sprot)


AMPC_ECOLI Beta-lactamase (sprot)

A beta-lactamase that is encoded in the genome of Escherichia coli K-12.


name: UNG_HUMAN Uracil-DNA glycosylase (sprot)

description: A uracil-DNA glycosylase that is encoded in the genome of human.


name: HDAC9_HUMAN Histone deacetylase 9 (sprot)

description: A histone deacetylase 9 that is encoded in the genome of human.


name: TTK_HUMAN Dual specificity protein kinase TTK (sprot)

description: A dual specificity protein kinase TTK that is encoded in the genome of human.


name: GPER1_HUMAN G-protein coupled estrogen receptor 1 (sprot)

description: A G-protein coupled estrogen receptor 1 that is encoded in the genome of human.


name: MTNN_KLEP3 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase (sprot)


name: MTNN_STAAC 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase (sprot)


name: FPPS_HUMAN Farnesyl pyrophosphate synthase (sprot)

description: A farnesyl pyrophosphate synthase that is encoded in the genome of human.


CONDURITOL B EPOXIDE

A conduritol epoxide resulting from the formal epoxidation of the double bond of (+)-conduritol B.


name: DCPS_HUMAN m7GpppX diphosphatase (sprot)

description: A scavenger mRNA-decapping enzyme DcpS that is encoded in the genome of human.


name: HCK_HUMAN Tyrosine-protein kinase HCK (sprot)

description: A tyrosine-protein kinase HCK that is encoded in the genome of human.


OGA_HUMAN Protein O-GlcNAcase (sprot)

A protein O-GlcNAcase that is encoded in the genome of human.


name: HEXB_HUMAN Beta-hexosaminidase subunit beta (sprot)

description: A beta-hexosaminidase subunit beta that is encoded in the genome of human.


L-tyrosine

An optically active form of tyrosine having L-configuration.


name: TTL_HUMAN Tubulin--tyrosine ligase (sprot)

description: A tubulin--tyrosine ligase that is encoded in the genome of human.


A nitrotyrosine comprising tyrosine having a nitro group at the 3-position on the phenyl ring.


name: MAP2_MOUSE Methionine aminopeptidase 2 (sprot)

description: A methionine aminopeptidase 2 that is encoded in the genome of mouse.


sirolimus

A macrolide lactam isolated from Streptomyces hygroscopicus consisting of a 29-membered ring containing 4 trans double bonds, three of which are conjugated. It is an antibiotic, immunosupressive and antineoplastic agent.


name: RXRA_HUMAN Retinoic acid receptor RXR-alpha (sprot)

description: A retinoic acid receptor RXR-alpha that is encoded in the genome of human.


2-aminoisobutanoic acid zwitterion

The zwitterionic form of 2-aminoisobutyric acid obtained by transfer of a proton from the carboxy to the amino group of L-valine; major species at pH 7.3.


name: ACCO1_MALDO 1-aminocyclopropane-1-carboxylate oxidase 1 (sprot)


DPEP1_HUMAN Dipeptidase 1 (sprot)

A dipeptidase 1 that is encoded in the genome of human.


GAG_HV1MN Gag polyprotein (sprot)

A lentivirus-type gag polyprotein that is encoded in the genome of Human immunodeficiency virus type 1 group M subtype B (isolate MN).


name: M4K1_HUMAN Mitogen-activated protein kinase kinase kinase kinase 1 (sprot)

description: A mitogen-activated protein kinase kinase kinase kinase 1 that is encoded in the genome of human.


name: M4K3_HUMAN Mitogen-activated protein kinase kinase kinase kinase 3 (sprot)

description: A mitogen-activated protein kinase kinase kinase kinase 3 that is encoded in the genome of human.


name: M4K5_HUMAN Mitogen-activated protein kinase kinase kinase kinase 5 (sprot)

description: A mitogen-activated protein kinase kinase kinase kinase 5 that is encoded in the genome of human.


name: MERTK_HUMAN Tyrosine-protein kinase Mer (sprot)

description: A tyrosine-protein kinase Mer that is encoded in the genome of human.


name: MKNK2_HUMAN MAP kinase-interacting serine/threonine-protein kinase 2 (sprot)

description: A MAP kinase-interacting serine/threonine-protein kinase 2 that is encoded in the genome of human.


name: STK4_HUMAN Serine/threonine-protein kinase 4 (sprot)

description: A serine/threonine-protein kinase 4 that is encoded in the genome of human.


tofacitinib

A pyrrolopyrimidine that is pyrrolo[2,3-d]pyrimidine substituted at position 4 by an N-methyl,N-(1-cyanoacetyl-4-methylpiperidin-3-yl)amino moiety. Used as its citrate salt to treat moderately to severely active rheumatoid arthritis.


name: MUSK_HUMAN Muscle, skeletal receptor tyrosine-protein kinase (sprot)

description: A muscle, skeletal receptor tyrosine-protein kinase that is encoded in the genome of human.


name: PGFRA_HUMAN Platelet-derived growth factor receptor alpha (sprot)

description: An alpha-type platelet-derived growth factor receptor that is encoded in the genome of human.


name: SLK_HUMAN STE20-like serine/threonine-protein kinase (sprot)

description: A STE20-like serine/threonine-protein kinase that is encoded in the genome of human.


name: STK33_HUMAN Serine/threonine-protein kinase 33 (sprot)

description: A serine/threonine-protein kinase 33 that is encoded in the genome of human.


name: TIE1_HUMAN Tyrosine-protein kinase receptor Tie-1 (sprot)

description: A tyrosine-protein kinase receptor Tie-1 that is encoded in the genome of human.


VDR_HUMAN Vitamin D3 receptor (sprot)

A vitamin D3 receptor that is encoded in the genome of human.


name: VTDB_RAT Vitamin D-binding protein (sprot)

description: A vitamin D-binding protein that is encoded in the genome of rat.


name: 2-(2-hydroxyethylamino)-9-isopropylpurine core C6-substituents, 42


name: 2-(2-hydroxyethylamino)-9-isopropylpurine core C6-substituents, 46


name: 2-(2-hydroxyethylamino)-9-isopropylpurine core C6-substituents, 53


name: 2-(2-hydroxyethylamino)-9-isopropylpurine core C6-substituents, 43


name: 2-(2-hydroxyethylamino)-9-isopropylpurine core C6-substituents, 54


name: 2-(2-hydroxyethylamino)-9-isopropylpurine core C6-substituents, 47


name: 2-(2-hydroxyethylamino)-9-isopropylpurine core C6-substituents, 44


name: 2-(2-hydroxyethylamino)-9-isopropylpurine core C6-substituents, 51


name: 2-(2-hydroxyethylamino)-9-isopropylpurine core C6-substituents, 52


name: 2-(2-hydroxyethylamino)-9-isopropylpurine core C6-substituents, 65


name: 2-(2-hydroxyethylamino)-9-isopropylpurine core C6-substituents, 45


name: 2-(2-hydroxyethylamino)-9-isopropylpurine core C6-substituents, 64


name: 6-(4-methoxybenzylamino) core C2-substituent, 118


name: 6-(4-methoxybenzylamino) core C2-substituent, 13


name: 6-(4-methoxybenzylamino) core C2-substituent, 15


name: 6-(4-methoxybenzylamino) core C2-substituent, 41


name: 6-(4-methoxybenzylamino) core C2-substituent, 50


name: 6-(4-methoxybenzylamino) core C2-substituent, 37


name: 6-(4-methoxybenzylamino) core C2-substituent, 28


name: 6-(4-methoxybenzylamino) core C2-substituent, 12


name: 6-(4-methoxybenzylamino) core C2-substituent, 11


name: 6-(4-methoxybenzylamino) core C2-substituent, 27


name: 6-(4-methoxybenzylamino) core C2-substituent, 38


name: 6-(4-methoxybenzylamino) core C2-substituent, 209


name: 6-(4-methoxybenzylamino) core C2-substituent, 26


name: 6-(4-methoxybenzylamino) core C2-substituent, 16


name: 6-(4-methoxybenzylamino) core C2-substituent, 211


name: 6-(4-methoxybenzylamino) core C2-substituent, 49


name: 6-(4-methoxybenzylamino) core C2-substituent, 40


name: 6-(4-methoxybenzylamino) core C2-substituent, 75


name: 6-(4-methoxybenzylamino) core C2-substituent, 76


name: 6-(4-methoxybenzylamino) core C2-substituent, 33


name: 6-(4-methoxybenzylamino) core C2-substituent, 36


name: 6-(4-methoxybenzylamino) core C2-substituent, 314


name: 6-(4-methoxybenzylamino) core C2-substituent, 10


name: 6-(3-chloroanilino)-9-isopropylpurine core C2-substituent, 309


name: 6-(3-chloroanilino)-9-isopropylpurine core C2-substituent, 304


name: 6-(3-chloroanilino)-9-isopropylpurine core C2-substituent, 305


name: 6-(3-chloroanilino)-9-isopropylpurine core C2-substituent, 303


name: 6-(3-chloroanilino)-9-isopropylpurine core C2-substituent, 302


name: 6-(3-chloroanilino)-9-isopropylpurine core C2-substituent, 310


name: 6-(3-chloroanilino)-9-isopropylpurine core C2-substituent, 60


name: 6-(3-chloroanilino)-9-isopropylpurine core C2-substituent, 58


name: 6-(3-chloroanilino)-9-isopropylpurine core C2-substituent, 307


name: 6-(3-chloroanilino)-9-isopropylpurine core C2-substituent, 308


name: 6-(3-chloroanilino)-9-isopropylpurine core C2-substituent, 71


name: 2-(2-hydroxyethylpiperidyl)-9-isopropylpurine core C6-substituent, 306


name: 6-(3-chloroanilino)-9-isopropylpurine core C2-substituent, 318


name: 6-(3-chloroanilino)-9-isopropylpurine core C2-substituent, 66


name: 6-(3-chloroanilino)-9-isopropylpurine core C2-substituent, 59


name: 6-(3-chloroanilino)-9-isopropylpurine core C2-substituent, 61


name: 6-(3-chloroanilino)-9-isopropylpurine core C2-substituent, 62


name: 6-(3-chloroanilino)-9-isopropylpurine core C2-substituent, 67


name: 6-(3-chloroanilino)-9-isopropylpurine core C2-substituent, 70


name: 6-(3-chloroanilino)-9-isopropylpurine core C2-substituent, 68


name: 6-(3-chloroanilino)-9-isopropylpurine core C2-substituent, 69


name: 6-(3-chloroanilino)-9-isopropylpurine core C2-substituent, 110


name: 6-(3-chloroanilino)-9-isopropylpurine core C2-substituent, 106


name: 2-(1 R-isopropyl-2-hydroxyethylamino)-9-isopropylpurine core C6-substituent, 78


name: 2-(1 R-isopropyl-2-hydroxyethylamino)-9-isopropylpurine core C6-substituent, 97


name: 2-(1 R-isopropyl-2-hydroxyethylamino)-9-isopropylpurine core C6-substituent, 95


name: 2-(1 R-isopropyl-2-hydroxyethylamino)-9-isopropylpurine core C6-substituent, 96


name: 2-(1 R-isopropyl-2-hydroxyethylamino)-9-isopropylpurine core C6-substituent, 77


name: 2-(1 R-isopropyl-2-hydroxyethylamino)-9-isopropylpurine core C6-substituent, 94


name: 2-(1 R-isopropyl-2-hydroxyethylamino)-9-isopropylpurine core C6-substituent, 98


name: 2-(1 R-isopropyl-2-hydroxyethylamino)-9-isopropylpurine core C6-substituent, 73


name: 2-(1 R-isopropyl-2-hydroxyethylamino)-9-isopropylpurine core C6-substituent, 356


name: 2-(1 R-isopropyl-2-hydroxyethylamino)-9-isopropylpurine core C6-substituent, 112


name: 2-(2-hydroxyethylpiperidyl)-9-isopropylpurine core C6-substituent, 212


name: 2-(2-hydroxyethylpiperidyl)-9-isopropylpurine core C6-substituent, 113


name: 2-(2-hydroxyethylpiperidyl)-9-isopropylpurine core C6-substituent, 222


name: 2-(2-hydroxyethylpiperidyl)-9-isopropylpurine core C6-substituent, 226


name: 2-(2-hydroxyethylpiperidyl)-9-isopropylpurine core C6-substituent, 220


name: 2-(2-hydroxyethylpiperidyl)-9-isopropylpurine core C6-substituent, 359


name: 2-(2-hydroxyethylpiperidyl)-9-isopropylpurine core C6-substituent, 219


name: 2-(2-hydroxyethylpiperidyl)-9-isopropylpurine core C6-substituent, 223


name: 2-(2-hydroxyethylpiperidyl)-9-isopropylpurine core C6-substituent, 224


name: 2-(2-hydroxyethylpiperidyl)-9-isopropylpurine core C6-substituent, 225


name: 2-((1 R-isopropyl)-2-hydroxyethylamino)-6-(3-chloroanilino)-9-isopropylpurine core C2-substituent, 312


name: 2-((1 R-isopropyl)-2-hydroxyethylamino)-6-(3-chloroanilino)-9-isopropylpurine core C2-substituent, 301


name: 2-((1 R-isopropyl)-2-hydroxyethylamino)-6-(3-chloroanilino)-9-isopropylpurine core C2-substituent, 311


name: 2-((1 R-isopropyl)-2-hydroxyethylamino)-6-(3-chloroanilino)-9-isopropylpurine core C2-substituent, 316


name: 2-((1 R-isopropyl)-2-hydroxyethylamino)-6-(3-chloroanilino)-9-isopropylpurine core C2-substituent, 313


A carboxamide resulting from the formal condensation of the carboxy group of 5,5-dimethyl-8-(quinolin-3-yl)-5,6-dihydronaphthalene-2-carboxylic acid with the amino group of p-aminobenzoic acid. It is a neutral retinoic acid receptor (RAR) alpha-selective antagonist (Ki = 2.5 nM). It displays no significant effect on nuclear receptor corepressor (NCoR) binding; moderately decreases SMRT binding to RAR. It antagonizes agonist-induced coactivator (CoA) recruitment.


BMS 753 is an isotype-selective retinoic acid receptor alpha (RARalpha) agonist


name: NTRK3_HUMAN NT-3 growth factor receptor (sprot)

description: An NT-3 growth factor receptor that is encoded in the genome of human.


name: ST32B_HUMAN Serine/threonine-protein kinase 32B (sprot)

description: A serine/threonine-protein kinase 32B that is encoded in the genome of human.


name: BLK_HUMAN Tyrosine-protein kinase Blk (sprot)

description: A tyrosine-protein kinase BLK that is encoded in the genome of human.


name: CTRO_HUMAN Citron Rho-interacting kinase (sprot)

description: A citron Rho-interacting kinase that is encoded in the genome of human.


name: FGFR4_HUMAN Fibroblast growth factor receptor 4 (sprot)

description: A fibroblast growth factor receptor 4 that is encoded in the genome of human.


name: FGR_HUMAN Tyrosine-protein kinase Fgr (sprot)

description: A tyrosine-protein kinase Fgr that is encoded in the genome of human.


name: E2AK4_HUMAN eIF-2-alpha kinase GCN2 (sprot)

description: An eIF-2-alpha kinase GCN2 that is encoded in the genome of human.


name: LYN_HUMAN Tyrosine-protein kinase Lyn (sprot)

description: A tyrosine-protein kinase Lyn that is encoded in the genome of human.


name: TNI3K_HUMAN Serine/threonine-protein kinase TNNI3K (sprot)

description: A serine/threonine-protein kinase TNNI3K that is encoded in the genome of human.


name: M3K20_HUMAN Mitogen-activated protein kinase kinase kinase 20 (sprot)

description: A mitogen-activated protein kinase kinase kinase 20 that is encoded in the genome of human.


name: ABL2_HUMAN Tyrosine-protein kinase ABL2 (sprot)

description: A tyrosine-protein kinase ABL2 that is encoded in the genome of human.


name: AAPK1_HUMAN 5'-AMP-activated protein kinase catalytic subunit alpha-1 (sprot)

description: A 5'-AMP-activated protein kinase catalytic subunit alpha-1 that is encoded in the genome of human.


name: ANKK1_HUMAN Ankyrin repeat and protein kinase domain-containing protein 1 (sprot)

description: An ankyrin repeat and protein kinase domain-containing protein 1 that is encoded in the genome of human.


name: KCC1A_HUMAN Calcium/calmodulin-dependent protein kinase type 1 (sprot)

description: A calcium/calmodulin-dependent protein kinase type 1 that is encoded in the genome of human.


name: KCC4_HUMAN Calcium/calmodulin-dependent protein kinase type IV (sprot)

description: A calcium/calmodulin-dependent protein kinase type IV that is encoded in the genome of human.


name: KKCC1_HUMAN Calcium/calmodulin-dependent protein kinase kinase 1 (sprot)

description: A calcium/calmodulin-dependent protein kinase kinase 1 that is encoded in the genome of human.


name: KKCC2_HUMAN Calcium/calmodulin-dependent protein kinase kinase 2 (sprot)

description: A calcium/calmodulin-dependent protein kinase kinase 2 that is encoded in the genome of human.


name: CDK3_HUMAN Cyclin-dependent kinase 3 (sprot)

description: A cyclin-dependent kinase 3 that is encoded in the genome of human.


name: CDK5_HUMAN Cyclin-dependent kinase 5 (sprot)

description: A cyclin-dependent kinase 5 that is encoded in the genome of human.


name: KC1D_HUMAN Casein kinase I isoform delta (sprot)

description: A casein kinase I isoform delta that is encoded in the genome of human.


A member of the class of benzamides that is 4-(imidazol-2-yl)benzamide carrying additional 1,3-benzodioxol-5-yl and pyridin-2-yl substituents at positions 4 and 5 respectively on the imidazole ring.


name: KC1E_HUMAN Casein kinase I isoform epsilon (sprot)

description: A casein kinase I isoform epsilon that is encoded in the genome of human.


name: KC1G2_HUMAN Casein kinase I isoform gamma-2 (sprot)

description: A casein kinase I isoform gamma-2 that is encoded in the genome of human.


name: KC1G3_HUMAN Casein kinase I isoform gamma-3 (sprot)

description: A casein kinase I isoform gamma-3 that is encoded in the genome of human.


name: DAPK3_HUMAN Death-associated protein kinase 3 (sprot)

description: A death-associated protein kinase 3 that is encoded in the genome of human.


name: M3K12_HUMAN Mitogen-activated protein kinase kinase kinase 12 (sprot)

description: A mitogen-activated protein kinase kinase kinase 12 that is encoded in the genome of human.


name: EPHA2_HUMAN Ephrin type-A receptor 2 (sprot)

description: An ephrin type-A receptor 2 that is encoded in the genome of human.


name: EPHA4_HUMAN Ephrin type-A receptor 4 (sprot)

description: An ephrin type-A receptor 4 that is encoded in the genome of human.


name: EPHA5_HUMAN Ephrin type-A receptor 5 (sprot)

description: An ephrin type-A receptor 5 that is encoded in the genome of human.


name: EPHA8_HUMAN Ephrin type-A receptor 8 (sprot)

description: An ephrin type-A receptor 8 that is encoded in the genome of human.


name: EPHB1_HUMAN Ephrin type-B receptor 1 (sprot)

description: An ephrin type-B receptor 1 that is encoded in the genome of human.


name: EPHB2_HUMAN Ephrin type-B receptor 2 (sprot)

description: An ephrin type-B receptor 2 that is encoded in the genome of human.


name: FER_HUMAN Tyrosine-protein kinase Fer (sprot)

description: A tyrosine-protein kinase Fer that is encoded in the genome of human.


name: FES_HUMAN Tyrosine-protein kinase Fes/Fps (sprot)

description: A tyrosine-protein kinase Fes/Fps that is encoded in the genome of human.


name: GAK_HUMAN Cyclin-G-associated kinase (sprot)

description: A cyclin-G-associated kinase that is encoded in the genome of human.


name: LATS1_HUMAN Serine/threonine-protein kinase LATS1 (sprot)

description: A serine/threonine-protein kinase LATS1 that is encoded in the genome of human.


name: MELK_HUMAN Maternal embryonic leucine zipper kinase (sprot)

description: A maternal embryonic leucine zipper kinase that is encoded in the genome of human.


name: MYLK2_HUMAN Myosin light chain kinase 2, skeletal/cardiac muscle (sprot)

description: A myosin light chain kinase 2, skeletal/cardiac muscle that is encoded in the genome of human.


MYO3A_HUMAN Myosin-IIIa (sprot)

A myosin-IIIa that is encoded in the genome of human.


MYO3B_HUMAN Myosin-IIIb (sprot)

A myosin-IIIB that is encoded in the genome of human.


name: NEK5_HUMAN Serine/threonine-protein kinase Nek5 (sprot)

description: A serine/threonine-protein kinase Nek5 that is encoded in the genome of human.


name: NLK_HUMAN Serine/threonine-protein kinase NLK (sprot)

description: A serine/threonine-protein kinase NLK that is encoded in the genome of human.


name: CDK16_HUMAN Cyclin-dependent kinase 16 (sprot)

description: A cyclin-dependent kinase 16 that is encoded in the genome of human.


name: CDK17_HUMAN Cyclin-dependent kinase 17 (sprot)

description: A cyclin-dependent kinase 17 that is encoded in the genome of human.


name: CDK18_HUMAN Cyclin-dependent kinase 18 (sprot)

description: A cyclin-dependent kinase 18 that is encoded in the genome of human.


name: CDK14_HUMAN Cyclin-dependent kinase 14 (sprot)

description: A cyclin-dependent kinase 14 that is encoded in the genome of human.


name: KAPCB_HUMAN cAMP-dependent protein kinase catalytic subunit beta (sprot)

description: A cAMP-dependent protein kinase catalytic subunit beta that is encoded in the genome of human.


name: KPCD2_HUMAN Serine/threonine-protein kinase D2 (sprot)

description: A serine/threonine-protein kinase D2 that is encoded in the genome of human.


name: KPCD3_HUMAN Serine/threonine-protein kinase D3 (sprot)

description: A serine/threonine-protein kinase D3 that is encoded in the genome of human.


name: E2AK2_HUMAN Interferon-induced, double-stranded RNA-activated protein kinase (sprot)

description: An interferon-induced, double-stranded RNA-activated protein kinase that is encoded in the genome of human.


name: FAK2_HUMAN Protein-tyrosine kinase 2-beta (sprot)

description: A focal adhesion kinase 2 that is encoded in the genome of human.


name: RIPK2_HUMAN Receptor-interacting serine/threonine-protein kinase 2 (sprot)

description: A receptor-interacting serine/threonine-protein kinase 2 that is encoded in the genome of human.


name: ROS1_HUMAN Proto-oncogene tyrosine-protein kinase ROS (sprot)

description: A proto-oncogene tyrosine-protein kinase ROS that is encoded in the genome of human.


name: SIK1_HUMAN Serine/threonine-protein kinase SIK1 (sprot)

description: A serine/threonine-protein kinase SIK1 that is encoded in the genome of human.


name: SRMS_HUMAN Tyrosine-protein kinase Srms (sprot)

description: A tyrosine-protein kinase Srms that is encoded in the genome of human.


name: STK36_HUMAN Serine/threonine-protein kinase 36 (sprot)

description: A serine/threonine-protein kinase 36 that is encoded in the genome of human.


name: TESK1_HUMAN Dual specificity testis-specific protein kinase 1 (sprot)

description: A dual specificity testis-specific protein kinase 1 that is encoded in the genome of human.


name: TGFR2_HUMAN TGF-beta receptor type-2 (sprot)

description: A TGF-beta receptor type-2 that is encoded in the genome of human.


name: TNIK_HUMAN TRAF2 and NCK-interacting protein kinase (sprot)

description: A TRAF2 and NCK-interacting protein kinase that is encoded in the genome of human.


name: TNK1_HUMAN Non-receptor tyrosine-protein kinase TNK1 (sprot)

description: A non-receptor tyrosine-protein kinase TNK1 that is encoded in the genome of human.


name: TYK2_HUMAN Non-receptor tyrosine-protein kinase TYK2 (sprot)

description: A non-receptor tyrosine-protein kinase TYK2 that is encoded in the genome of human.


name: YES_HUMAN Tyrosine-protein kinase Yes (sprot)

description: A tyrosine-protein kinase Yes that is encoded in the genome of human.


name: STK25_HUMAN Serine/threonine-protein kinase 25 (sprot)

description: A serine/threonine-protein kinase 25 that is encoded in the genome of human.


name: MK11_HUMAN Mitogen-activated protein kinase 11 (sprot)

description: A mitogen-activated protein kinase 11 that is encoded in the genome of human.


name: MK12_HUMAN Mitogen-activated protein kinase 12 (sprot)

description: A mitogen-activated protein kinase 12 that is encoded in the genome of human.


name: MP2K2_HUMAN Dual specificity mitogen-activated protein kinase kinase 2 (sprot)

description: A dual specificity mitogen-activated protein kinase kinase 2 that is encoded in the genome of human.


name: MRCKG_HUMAN Serine/threonine-protein kinase MRCK gamma (sprot)

description: A serine/threonine-protein kinase MRCK gamma that is encoded in the genome of human.


name: EPHA1_HUMAN Ephrin type-A receptor 1 (sprot)

description: An ephrin type-A receptor 1 that is encoded in the genome of human.


name: MRCKB_HUMAN Serine/threonine-protein kinase MRCK beta (sprot)

description: A serine/threonine-protein kinase MRCK beta that is encoded in the genome of human.


name: DCLK1_HUMAN Serine/threonine-protein kinase DCLK1 (sprot)

description: A serine/threonine-protein kinase DCLK1 that is encoded in the genome of human.


name: DCLK2_HUMAN Serine/threonine-protein kinase DCLK2 (sprot)

description: A serine/threonine-protein kinase DCLK2 that is encoded in the genome of human.


name: DCLK3_HUMAN Serine/threonine-protein kinase DCLK3 (sprot)

description: A serine/threonine-protein kinase DCLK3 that is encoded in the genome of human.


name: ST17A_HUMAN Serine/threonine-protein kinase 17A (sprot)

description: A serine/threonine-protein kinase 17A that is encoded in the genome of human.


name: DYR1B_HUMAN Dual specificity tyrosine-phosphorylation-regulated kinase 1B (sprot)

description: A dual specificity tyrosine-phosphorylation-regulated kinase 1B that is encoded in the genome of human.


name: MK06_HUMAN Mitogen-activated protein kinase 6 (sprot)

description: A mitogen-activated protein kinase 6 that is encoded in the genome of human.


name: MK04_HUMAN Mitogen-activated protein kinase 4 (sprot)

description: A mitogen-activated protein kinase 4 that is encoded in the genome of human.


name: MK07_HUMAN Mitogen-activated protein kinase 7 (sprot)

description: A mitogen-activated protein kinase 7 that is encoded in the genome of human.


name: IRAK3_HUMAN Interleukin-1 receptor-associated kinase 3 (sprot)

description: An interleukin-1 receptor-associated kinase 3 that is encoded in the genome of human.


name: MYLK3_HUMAN Myosin light chain kinase 3 (sprot)

description: A myosin light chain kinase 3 that is encoded in the genome of human.


name: PAK3_HUMAN Serine/threonine-protein kinase PAK 3 (sprot)

description: A serine/threonine-protein kinase PAK 3 that is encoded in the genome of human.


name: PHKG1_HUMAN Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform (sprot)

description: A phosphorylase b kinase gamma catalytic chain, skeletal muscle isoform that is encoded in the genome of human.


name: NUAK2_HUMAN NUAK family SNF1-like kinase 2 (sprot)

description: A NUAK family SNF1-like kinase 2 that is encoded in the genome of human.


name: AAK1_HUMAN AP2-associated protein kinase 1 (sprot)

description: An AAK1 gene translation product (human), isoforms h1 and h2.


name: AAPK2_HUMAN 5'-AMP-activated protein kinase catalytic subunit alpha-2 (sprot)

description: A 5'-AMP-activated protein kinase catalytic subunit alpha-2 that is encoded in the genome of human.


name: NUAK1_HUMAN NUAK family SNF1-like kinase 1 (sprot)

description: A NUAK family SNF1-like kinase 1 that is encoded in the genome of human.


name: BMP2K_HUMAN BMP-2-inducible protein kinase (sprot)

description: A BMP-2-inducible protein kinase that is encoded in the genome of human.


name: CSK22_HUMAN Casein kinase II subunit alpha' (sprot)

description: A casein kinase II subunit alpha' that is encoded in the genome of human.


name: ST17B_HUMAN Serine/threonine-protein kinase 17B (sprot)

description: A serine/threonine-protein kinase 17B that is encoded in the genome of human.


name: JAK1_HUMAN Tyrosine-protein kinase JAK1 (sprot)

description: A tyrosine-protein kinase JAK1 that is encoded in the genome of human.


name: STK11_HUMAN Serine/threonine-protein kinase STK11 (sprot)

description: A serine/threonine-protein kinase STK11 that is encoded in the genome of human.


name: M3K4_HUMAN Mitogen-activated protein kinase kinase kinase 4 (sprot)

description: A mitogen-activated protein kinase kinase kinase 4 that is encoded in the genome of human.


name: MARK1_HUMAN Serine/threonine-protein kinase MARK1 (sprot)

description: A serine/threonine-protein kinase MARK1 that is encoded in the genome of human.


name: MARK2_HUMAN Serine/threonine-protein kinase MARK2 (sprot)

description: A serine/threonine-protein kinase MARK2 that is encoded in the genome of human.


name: MARK4_HUMAN MAP/microtubule affinity-regulating kinase 4 (sprot)

description: A MAP/microtubule affinity-regulating kinase 4 that is encoded in the genome of human.


name: STK24_HUMAN Serine/threonine-protein kinase 24 (sprot)

description: A serine/threonine-protein kinase 24 that is encoded in the genome of human.


name: STK26_HUMAN Serine/threonine-protein kinase 26 (sprot)

description: A serine/threonine-protein kinase 26 that is encoded in the genome of human.


name: MYLK_HUMAN Myosin light chain kinase, smooth muscle (sprot)

description: A myosin light chain kinase, smooth muscle that is encoded in the genome of human.


name: NEK2_HUMAN Serine/threonine-protein kinase Nek2 (sprot)

description: A serine/threonine-protein kinase Nek2 that is encoded in the genome of human.


name: NEK6_HUMAN Serine/threonine-protein kinase Nek6 (sprot)

description: A serine/threonine-protein kinase Nek6 that is encoded in the genome of human.


name: NEK7_HUMAN Serine/threonine-protein kinase Nek7 (sprot)

description: A serine/threonine-protein kinase Nek7 that is encoded in the genome of human.


name: NEK9_HUMAN Serine/threonine-protein kinase Nek9 (sprot)

description: A serine/threonine-protein kinase Nek9 that is encoded in the genome of human.


name: PHKG2_HUMAN Phosphorylase b kinase gamma catalytic chain, liver/testis isoform (sprot)

description: A phosphorylase b kinase gamma catalytic chain, liver/testis isoform that is encoded in the genome of human.


name: PI51A_HUMAN Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha (sprot)

description: A phosphatidylinositol 4-phosphate 5-kinase type-1 alpha that is encoded in the genome of human.


name: PI42B_HUMAN Phosphatidylinositol 5-phosphate 4-kinase type-2 beta (sprot)

description: A phosphatidylinositol 5-phosphate 4-kinase type-2 beta that is encoded in the genome of human.


name: PKN1_HUMAN Serine/threonine-protein kinase N1 (sprot)

description: A serine/threonine-protein kinase N1 that is encoded in the genome of human.


name: PKN2_HUMAN Serine/threonine-protein kinase N2 (sprot)

description: A serine/threonine-protein kinase N2 that is encoded in the genome of human.


name: RIOK1_HUMAN Serine/threonine-protein kinase RIO1 (sprot)

description: A serine/threonine-protein kinase RIO1 that is encoded in the genome of human.


name: RIOK3_HUMAN Serine/threonine-protein kinase RIO3 (sprot)

description: A serine/threonine-protein kinase RIO3 that is encoded in the genome of human.


name: SIK2_HUMAN Serine/threonine-protein kinase SIK2 (sprot)

description: A serine/threonine-protein kinase SIK2 that is encoded in the genome of human.


name: SRPK1_HUMAN SRSF protein kinase 1 (sprot)

description: An SRSF protein kinase 1 that is encoded in the genome of human.


name: SRPK2_HUMAN SRSF protein kinase 2 (sprot)

description: An SRSF protein kinase 2 that is encoded in the genome of human.


name: MYLK4_HUMAN Myosin light chain kinase family member 4 (sprot)

description: A myosin light chain kinase family member 4 that is encoded in the genome of human.


name: TLK2_HUMAN Serine/threonine-protein kinase tousled-like 2 (sprot)

description: A serine/threonine-protein kinase tousled-like 2 that is encoded in the genome of human.


name: TYRO3_HUMAN Tyrosine-protein kinase receptor TYRO3 (sprot)

description: A tyrosine-protein kinase receptor TYRO3 that is encoded in the genome of human.


name: WEE1_HUMAN Wee1-like protein kinase (sprot)

description: A Wee1-like protein kinase that is encoded in the genome of human.


name: COQ8A_HUMAN Atypical kinase COQ8A, mitochondrial (sprot)

description: An atypical kinase COQ8A, mitochondrial that is encoded in the genome of human.


name: COQ8B_HUMAN Atypical kinase COQ8B, mitochondrial (sprot)

description: An atypical kinase COQ8B, mitochondrial that is encoded in the genome of human.


name: TEC_HUMAN Tyrosine-protein kinase Tec (sprot)

description: A tyrosine-protein kinase Tec that is encoded in the genome of human.


name: TXK_HUMAN Tyrosine-protein kinase TXK (sprot)

description: A tyrosine-protein kinase TXK that is encoded in the genome of human.


name: ACV1B_HUMAN Activin receptor type-1B (sprot)

description: An activin receptor type-1B that is encoded in the genome of human.


name: AVR2A_HUMAN Activin receptor type-2A (sprot)

description: An activin receptor type-2A that is encoded in the genome of human.


name: AVR2B_HUMAN Activin receptor type-2B (sprot)

description: An activin receptor type-2B that is encoded in the genome of human.


name: ACVL1_HUMAN Serine/threonine-protein kinase receptor R3 (sprot)

description: A serine/threonine-protein kinase receptor R3 that is encoded in the genome of human.


name: DMPK_HUMAN Myotonin-protein kinase (sprot)

description: A myotonin-protein kinase that is encoded in the genome of human.


LIMK1_HUMAN LIM domain kinase 1 (sprot)

A LIM domain kinase 1 that is encoded in the genome of human.


name: PMYT1_HUMAN Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (sprot)

description: A membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase that is encoded in the genome of human.


name: KCC1D_HUMAN Calcium/calmodulin-dependent protein kinase type 1D (sprot)

description: A calcium/calmodulin-dependent protein kinase type 1D that is encoded in the genome of human.


name: CLK3_HUMAN Dual specificity protein kinase CLK3 (sprot)

description: A dual specificity protein kinase CLK3 that is encoded in the genome of human.


name: KC1AL_HUMAN Casein kinase I isoform alpha-like (sprot)

description: A casein kinase I isoform alpha-like that is encoded in the genome of human.


name: NEK1_HUMAN Serine/threonine-protein kinase Nek1 (sprot)

description: A serine/threonine-protein kinase Nek1 that is encoded in the genome of human.


name: PAK1_HUMAN Serine/threonine-protein kinase PAK 1 (sprot)

description: A serine/threonine-protein kinase PAK 1 that is encoded in the genome of human.


name: KCC2A_HUMAN Calcium/calmodulin-dependent protein kinase type II subunit alpha (sprot)

description: A calcium/calmodulin-dependent protein kinase type II subunit alpha that is encoded in the genome of human.


name: KCC1G_HUMAN Calcium/calmodulin-dependent protein kinase type 1G (sprot)

description: A calcium/calmodulin-dependent protein kinase type 1G that is encoded in the genome of human.


name: MP2K4_HUMAN Dual specificity mitogen-activated protein kinase kinase 4 (sprot)

description: A dual specificity mitogen-activated protein kinase kinase 4 that is encoded in the genome of human.


name: MP2K6_HUMAN Dual specificity mitogen-activated protein kinase kinase 6 (sprot)

description: A dual specificity mitogen-activated protein kinase kinase 6 that is encoded in the genome of human.


name: STK16_HUMAN Serine/threonine-protein kinase 16 (sprot)

description: A serine/threonine-protein kinase 16 that is encoded in the genome of human.


name: BRSK1_HUMAN Serine/threonine-protein kinase BRSK1 (sprot)

description: A serine/threonine-protein kinase BRSK1 that is encoded in the genome of human.


name: BRSK2_HUMAN Serine/threonine-protein kinase BRSK2 (sprot)

description: A serine/threonine-protein kinase BRSK2 that is encoded in the genome of human.


name: KC1G1_HUMAN Casein kinase I isoform gamma-1 (sprot)

description: A casein kinase I isoform gamma-1 that is encoded in the genome of human.


name: MP2K3_HUMAN Dual specificity mitogen-activated protein kinase kinase 3 (sprot)

description: A dual specificity mitogen-activated protein kinase kinase 3 that is encoded in the genome of human.


name: PAK6_HUMAN Serine/threonine-protein kinase PAK 6 (sprot)

description: A serine/threonine-protein kinase PAK 6 that is encoded in the genome of human.


name: PAK5_HUMAN Serine/threonine-protein kinase PAK 5 (sprot)

description: A serine/threonine-protein kinase PAK 5 that is encoded in the genome of human.


name: TLK1_HUMAN Serine/threonine-protein kinase tousled-like 1 (sprot)

description: A serine/threonine-protein kinase tousled-like 1 that is encoded in the genome of human.


name: KCC2D_HUMAN Calcium/calmodulin-dependent protein kinase type II subunit delta (sprot)

description: A calcium/calmodulin-dependent protein kinase type II subunit delta that is encoded in the genome of human.


name: KCC2G_HUMAN Calcium/calmodulin-dependent protein kinase type II subunit gamma (sprot)

description: A calcium/calmodulin-dependent protein kinase type II subunit gamma that is encoded in the genome of human.


name: DAPK1_HUMAN Death-associated protein kinase 1 (sprot)

description: A death-associated protein kinase 1 that is encoded in the genome of human.


name: KGP2_HUMAN cGMP-dependent protein kinase 2 (sprot)

description: A cGMP-dependent protein kinase 2 that is encoded in the genome of human.


name: DAPK2_HUMAN Death-associated protein kinase 2 (sprot)

description: A death-associated protein kinase 2 that is encoded in the genome of human.


name: KCC2B_HUMAN Calcium/calmodulin-dependent protein kinase type II subunit beta (sprot)

description: A calcium/calmodulin-dependent protein kinase type II subunit beta that is encoded in the genome of human.


name: PAK2_HUMAN Serine/threonine-protein kinase PAK 2 (sprot)

description: A serine/threonine-protein kinase PAK 2 that is encoded in the genome of human.


name: KGP1_HUMAN cGMP-dependent protein kinase 1 (sprot)

description: A cGMP-dependent protein kinase 1 that is encoded in the genome of human.


name: PRKX_HUMAN cAMP-dependent protein kinase catalytic subunit PRKX (sprot)

description: A serine/threonine-protein kinase PRKX that is encoded in the genome of human.


name: TSSK1_HUMAN Testis-specific serine/threonine-protein kinase 1 (sprot)

description: A testis-specific serine/threonine-protein kinase 1 that is encoded in the genome of human.


name: ST38L_HUMAN Serine/threonine-protein kinase 38-like (sprot)

description: A serine/threonine-protein kinase 38-like that is encoded in the genome of human.


name: BMR1A_HUMAN Bone morphogenetic protein receptor type-1A (sprot)

description: A BMP receptor type-1A that is encoded in the genome of human.


name: MK03_HUMAN Mitogen-activated protein kinase 3 (sprot)

description: A mitogen-activated protein kinase 3 that is encoded in the genome of human.


name: M3K5_HUMAN Mitogen-activated protein kinase kinase kinase 5 (sprot)

description: A mitogen-activated protein kinase kinase kinase 5 that is encoded in the genome of human.


name: ((4-Fluoro-phenyl)-{2-[5-(3-methoxy-phenyl)-[1,3,4]oxadiazol-2-ylsulfanyl]-acetyl}-amino)-acetic acid ethyl ester


name: 4-(4-fluorophenyl)-2-keto-6-methyl-3,4-dihydro-1H-pyrimidine-5-carboxylic acid piperonyl ester


name: 2-[(Furan-2-carbonyl)-amino]-benzothiazole-6-carboxylic acid ethyl ester


name: [6-(2-Methoxy-phenylcarbamoyl)-2,2-dimethyl-3-oxo-2,3-dihydro-benzo[1,4]oxazin-4-yl]-acetic acid ethyl ester


name: 4-{4-[2-(3-Methyl-4-oxo-3,4-dihydro-phthalazin-1-yl)-acetylamino]-phenyl}-piperazine-1-carboxylic acid tert-butyl ester


bithionol

An aryl sulfide that is diphenyl sulfide in which each phenyl group is substituted at position 2 by hydroxy and at positions 3 and 5 by chlorine. A fungicide and anthelmintic, it was used in various topical drug products for the treatment of liver flukes, but withdrawn after being shown to be a potent photosensitizer with the potential to cause serious skin disorders.


benzbromarone

1-Benzofuran substituted at C-2 and C-3 by an ethyl group and a 3,5-dibromo-4-hydroxybenzoyl group respectively. An inhibitor of CYP2C9, it is used as an anti-gout medication.


name: 4-(cyclohexylamino)-2-(3,5-dimethyl-1-pyrazolyl)-5-pyrimidinecarboxylic acid ethyl ester


name: 2-(1-benzimidazolyl)acetic acid [2-[1-(4-methoxyphenyl)-2,5-dimethyl-3-pyrrolyl]-2-oxoethyl] ester


name: 9-Hydroximinofluorene-4-carboxylic acid ethyl ester


name: 2-keto-6-methyl-4-phenyl-3,4-dihydro-1H-pyrimidine-5-carboxylic acid piperonyl ester


name: Phenothiazine-10-carbothioic acid S-(5-methyl-[1,3,4]thiadiazol-2-yl) ester


name: PANC_MYCTU Pantothenate synthetase (sprot)


name: 2-Amino-5-keto-4-o-phenetyl-4,6,7,8-tetrahydrochromene-3-carboxylic acid ethyl ester


name: MPIP2_HUMAN M-phase inducer phosphatase 2 (sprot)

description: An M-phase inducer phosphatase 2 that is encoded in the genome of human.


HD_HUMAN Huntingtin (sprot)

A huntingtin that is encoded in the genome of human.


name: FPR1_HUMAN fMet-Leu-Phe receptor (sprot)

description: An fMet-Leu-Phe receptor that is encoded in the genome of human.


ELLIPTECINE

A organic heterotetracyclic compound that is pyrido[4,3-b]carbazole carrying two methyl substituents at positions 5 and 11.


A member of the class of quinazolines that is quinazoline which is substituted at positions 2 and 4 by pyridin-4-yl and pyrrolidin-1-yl groups, respectively.


name: 4-[oxo-(pyridin-4-ylamino)methyl]-1H-imidazole-5-carboxylic acid ethyl ester


name: 1-Piperazinecarboxylic acid, 4-(1H-purin-6-yl)-, ethyl ester


name: RORA_HUMAN Nuclear receptor ROR-alpha (sprot)

description: A nuclear receptor ROR-alpha that is encoded in the genome of human.


name: 2,6-Dimethyl-benzo[1,2-b;4,5-b']difuran-3,7-dicarboxylic acid bis-(2-dimethylamino-ethyl) ester


podophyllotoxin

An organic heterotetracyclic compound that has a furonaphthodioxole skeleton bearing a 3,4,5-trimethoxyphenyl substituent. It is found in the roots and rhizomes of Podophyllum species and is used for the topical treatment of genital warts.


emetine

A pyridoisoquinoline comprising emetam having methoxy substituents at the 6'-, 7'-, 10- and 11-positions. It is an antiprotozoal agent and emetic. It inhibits SARS-CoV2, Zika and Ebola virus replication and displays antimalarial, antineoplastic and antiamoebic properties.


APHIDICOLIN

A tetracyclic diterpenoid that has an tetradecahydro-8,11a-methanocyclohepta[a]naphthalene skeleton with two hydroxymethyl substituents at positions 4 and 9, two methyl substituents at positions 4 and 11b and two hydroxy substituents at positions 3 and 9. An antibiotic with antiviral and antimitotical properties. Aphidicolin is a reversible inhibitor of eukaryotic nuclear DNA replication.


cladribine

2'-Deoxyadenosine in which the hydrogen at position 2 on the purine ring has been substituted by chlorine. It inhibits the synthesis and repair of DNA, particularly in  lymphocytes and monocytes, and is used as an antimetabolite antineoplastic drug for the treatment of lymphoid malignancies including  hairy-cell leukaemia and chronic lymphocytic leukaemia.


TERPYRIDINE

A tridentate heterocyclic ligand that binds metals at three meridional sites giving two adjacent 5-membered MN2C2 chelate rings.


name: 6-(1-benzimidazolylmethyl)-4-(2,5-dimethylphenyl)-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylic acid ethyl ester


name: PTN22_HUMAN Tyrosine-protein phosphatase non-receptor type 22 (sprot)

description: A tyrosine-protein phosphatase non-receptor type 22 that is encoded in the genome of human.


kinetin

A member of the class of 6-aminopurines that is  adenine carrying a (furan-2-ylmethyl) substituent at the exocyclic amino group.


sulfapyridine

A sulfonamide consisting of pyridine with a 4-aminobenzenesulfonamido group at the 2-position.


penicillamine

An optically active form of penicillamine having D-configuration. Pharmaceutical form (L-form is toxic) of chelating agent used to treat heavy metal poisoning.


name: 3-hydroxy-1-adamantanecarboxylic acid [2-[1-(2-methoxyethyl)-2,5-dimethyl-3-pyrrolyl]-2-oxoethyl] ester


name: 2,5-dimethyl-3-furancarboxylic acid [2-(2,3-dihydroindol-1-yl)-2-oxoethyl] ester


name: (3-Cyano-7-ethoxy-quinolin-2-ylsulfanyl)-acetic acid ethyl ester


name: PPBN_HUMAN Alkaline phosphatase, germ cell type (sprot)

description: An alkaline phosphatase, germ cell type that is encoded in the genome of human.


name: [[(4Z)-4-[[4-(dimethylamino)phenyl]methylidene]-5-oxo-2-thiazolyl]thio]formic acid ethyl ester


name: 2-[(5-oxo-3-sulfanylidene-2H-1,2,4-triazin-6-yl)amino]propanoic acid butyl ester


A pyridinium cation obtained by methylation at position 1 of 4-(4-dimethylaminostyryl)pyridine


name: (5E)-4-keto-2-methyl-5-vanillylidene-2-pyrroline-3-carboxylic acid methyl ester


name: 3-Hydroxy-3-phenyl-2-[3-(4-sulfamoyl-phenylcarbamoyl)-propionylamino]-propionic acid octyl ester


name: 5-[[(2-methylanilino)-sulfanylidenemethyl]amino]-1H-pyrazole-4-carboxylic acid methyl ester


name: 5-bromo-3-pyridinecarboxylic acid [3-(2-naphthalenyloxy)-4-oxo-1-benzopyran-7-yl] ester


name: N-[5-Methyl-3-O-tolyl-isoxazole-4-carboxylic acid amide] boronic acid


BLAC_STAAU Beta-lactamase (sprot)

A protein that is a translation product of any of the plasmid-encoded copies of the blaZ gene in Staphylococcus aureus.


BLAT_ECOLX Beta-lactamase TEM (sprot)

A protein that is a translation product of any of the plasmid-encoded copies of the blaTEM gene in Escherichia coli.


name: (3-Cyano-7-methyl-quinolin-2-ylsulfanyl)-acetic acid methyl ester


name: 1433G_HUMAN 14-3-3 protein gamma (sprot)

description: A 14-3-3 protein gamma that is encoded in the genome of human.


name: 2-phenoxybenzoic acid [2-(2-furanylmethylamino)-2-oxoethyl] ester


name: 3-[(4-methylphenyl)sulfamoyl]benzoic acid [2-(2-furanylmethylamino)-2-oxoethyl] ester


name: 2-(6-imidazo[2,1-b]thiazolyl)acetic acid 1,3-benzothiazol-2-ylmethyl ester


name: 2-(6,7-dihydro-5H-cyclopenta[f]benzofuran-3-yl)acetic acid (4-ketopyrimido[2,1-b][1,3]benzothiazol-2-yl)methyl ester


name: Benzoic acid, 4-amino-, 4-acetoxy-2,2,6,6-tetramethyl-1-piperidinyl ester


name: 2-[(4-methyl-5-sulfanylidene-1,3,4-thiadiazol-2-yl)thio]acetic acid ethyl ester


name: (7-Hydroxy-2-p-tolyl-pyrazolo[1,5-a]pyrimidin-5-yl)-acetic acid ethyl ester


name: 2-cyclopentylacetic acid [2-[(3-chloro-9,10-dioxo-2-anthracenyl)amino]-2-oxoethyl] ester


name: BAP1_HUMAN Ubiquitin carboxyl-terminal hydrolase BAP1 (sprot)

description: A ubiquitin carboxyl-terminal hydrolase BAP1 that is encoded in the genome of human.


name: 5-Acetyl-4-methyl-2-[2-(5-phenyl-tetrazol-2-yl)-acetylamino]-thiophene-3-carboxylic acid ethyl ester


name: SMAD3_HUMAN Mothers against decapentaplegic homolog 3 (sprot)

description: A smad3 that is encoded in the genome of human.


name: 1-Methanesulfonyl-2,3-dihydro-1H-indole-5-carboxylic acid 2-oxo-2-phenyl-ethyl ester


estriol 3-O-(beta-D-glucuronide)(1-)

A steroid glucuronide anion that is the conjugate base of estriol 3-O-(beta-D-glucuronide) arising from deprotonation of the carboxylic acid function; major species at pH 7.3.


name: Morpholine-4-carboxylic acid [3-(6-amino-5-cyano-3-ethyl-2,4-dihydropyrano[2,3-c]pyrazol-4-yl)phenyl] ester


A 4-hydroxy steroid that consists of 17beta-estradiol bearing an additional 6alpha-hydroxy substituent.


name: NR4A1_HUMAN Nuclear receptor subfamily 4immunitygroup A member 1 (sprot)

description: A nuclear receptor subfamily 4 immunity group A member 1 that is encoded in the genome of human.


name: 4-(2-Diethylamino-ethyl)-3,5-dimethyl-1H-pyrrole-2-carboxylic acid benzyl ester


name: 2-[(3-allyl-4-keto-7-methyl-6,8-dihydro-5H-pyrido[2,3]thieno[2,4-b]pyrimidin-2-yl)thio]acetic acid methyl ester


name: 3-(dimethylamino)benzoic acid (7-hydroxy-2-oxo-1-benzopyran-4-yl)methyl ester


name: HEXA_HUMAN Beta-hexosaminidase subunit alpha (sprot)

description: A beta-hexosaminidase subunit alpha that is encoded in the genome of human.


name: PPR1A_HUMAN Protein phosphatase 1 regulatory subunit 1A (sprot)

description: A protein phosphatase 1 regulatory subunit 1A that is encoded in the genome of human.


name: PTPA_HUMAN Serine/threonine-protein phosphatase 2A activator (sprot)

description: A serine/threonine-protein phosphatase 2A regulatory subunit B' that is encoded in the genome of human.


name: C1S_HUMAN Complement C1s subcomponent (sprot)

description: A complement C1s subcomponent that is encoded in the genome of human.


name: (2-Cyclopropyl-quinazolin-4-ylsulfanyl)-acetic acid ethyl ester


name: 9-Hydroximinofluorene-4-carboxylic acid methyl ester


name: (2-Isopropyl-quinazolin-4-ylsulfanyl)-acetic acid methyl ester


name: (2-Isopropyl-quinazolin-4-ylsulfanyl)-acetic acid ethyl ester


name: 2-[2-[(1-Ethyl-2-oxo-6-benzo[cd]indolyl)sulfonylamino]-4-thiazolyl]acetic acid ethyl ester


CATG_HUMAN Cathepsin G (sprot)

A cathepsin G that is encoded in the genome of human.


name: 2-[[(4-methyl-5-thieno[3,2-b]pyrrolyl)-oxomethyl]amino]benzoic acid methyl ester


name: OGRL1_HUMAN Opioid growth factor receptor-like protein 1 (sprot)

description: An opioid growth factor receptor-like protein 1 that is encoded in the genome of human.


name: HYES_HUMAN Bifunctional epoxide hydrolase 2 (sprot)

description: An epoxide hydrolase 2 that is encoded in the genome of human.


name: 3-[4-(3-Adamantan-1-yl-ureido)-piperidine-1-sulfonyl]-benzoic acid methyl ester


name: GALR2_HUMAN Galanin receptor type 2 (sprot)

description: A galanin receptor type 2 that is encoded in the genome of human.


FLUORESCEIN

A xanthene dye that is highly fluorescent and commonly used as a fluorescent tracer.


A nucleoside triphosphate(4-) obtained by global deprotonation of the triphosphate OH groups of ATP; major species present at pH 7.3.


name: G3P_HUMAN Glyceraldehyde-3-phosphate dehydrogenase (sprot)

description: A glyceraldehyde-3-phosphate dehydrogenase that is encoded in the genome of human.


The indol-3-yl carboxylic acid anion formed by loss of a proton from the carboxy group of (5-hydroxyindol-3-yl)acetic acid; principal microspecies at pH 7.3


name: YOPH_YEREN Tyrosine-protein phosphatase YopH (sprot)

description: A protein that is a translation product of the yopH gene in Yersinia enterocolitica.


name: NPY1R_HUMAN Neuropeptide Y receptor type 1 (sprot)

description: A neuropeptide Y receptor type 1 that is encoded in the genome of human.


name: 5-hydroxy-1-methyl-4-(4-morpholinylmethyl)-2-[(phenylthio)methyl]-3-indolecarboxylic acid ethyl ester


name: NPY2R_HUMAN Neuropeptide Y receptor type 2 (sprot)

description: A neuropeptide Y receptor type 2 that is encoded in the genome of human.


name: 9-Hydroximinofluorene-4-carboxylic acid isobutyl ester


name: (6-Bromo-2-ethyl-4-phenyl-4H-quinazolin-3-yl)-acetic acid methyl ester


name: N-phenylcarbamic acid [5-(2-chlorophenyl)-3-isoxazolyl]methyl ester


name: 2-{2-[4-(Furan-2-carbonyl)-piperazin-1-yl]-acetylamino}-benzoic acid methyl ester


name: Furan-2-carboxylic acid (2-methoxycarbonyl-phenylcarbamoyl)-methyl ester


name: 2-{2-[4-(2,3-Dihydro-benzo[1,4]dioxine-6-carbonyl)-piperidin-1-yl]-acetylamino}-benzoic acid methyl ester


name: 2-{2-[4-(2-Methyl-benzoylamino)-piperidin-1-yl]-acetylamino}-benzoic acid methyl ester


name: 3-{2-[4-(3,4,5-Trimethoxy-benzoylamino)-piperidin-1-yl]-acetylamino}-benzoic acid methyl ester


name: 2-amino-3-cyano-5,6,7,8-tetrahydroquinoline-4-carboxylic acid methyl ester


name: 5-Carbamoylmethoxy-2-methyl-benzofuran-3-carboxylic acid isopropyl ester


name: 3-[[(4-methoxyphenyl)-oxomethyl]amino]-2-thiophenecarboxylic acid methyl ester


name: 2-[[2-(4-morpholinyl)-1-oxoethyl]amino]-4-thiophen-2-yl-3-thiophenecarboxylic acid methyl ester


name: 2-[(1-oxo-2-phenoxyethyl)amino]benzoic acid methyl ester


name: NCOA1_HUMAN Nuclear receptor coactivator 1 (sprot)

description: A nuclear receptor coactivator 1 that is encoded in the genome of human.


name: (7-Cyano-[1,3]dioxolo[4,5-g]quinolin-6-ylsulfanyl)-acetic acid methyl ester


name: 2-[(3-methoxyphenyl)-oxomethyl]imino-3,4-dimethyl-5-thiazolecarboxylic acid ethyl ester


name: (7-Cyano-[1,3]dioxolo[4,5-g]quinolin-6-ylsulfanyl)-acetic acid isopropyl ester


name: 2-[2-[(3-chloro-1-benzothiophen-2-yl)-oxomethyl]imino-6-sulfamoyl-1,3-benzothiazol-3-yl]acetic acid ethyl ester


name: CDC42_HUMAN Cell division control protein 42 homolog (sprot)

description: A cell division control protein 42 that is encoded in the genome of human.


name: 2-(Phenethylthio)nicotinic acid methyl ester


name: RAB2A_CANLF Ras-related protein Rab-2A (sprot)

description: A Ras-related protein Rab-2A that is encoded in the genome of dog.


name: RAC1_MOUSE Ras-related C3 botulinum toxin substrate 1 (sprot)

description: A Ras-related C3 botulinum toxin substrate 1 that is encoded in the genome of mouse.


thiram

An organic disulfide that results from the formal oxidative dimerisation of N,N-dimethyldithiocarbamic acid. It is widely used as a fungicidal seed treatment.


name: N,N-dimethylcarbamodithioic acid (1-acetamido-2,2,2-trichloroethyl) ester


AROMATICIN

A sesquiterpene lactone that is 3,3a,4,4a,7a,8,9,9a-octahydroazuleno[6,5-b]furan-2,5-dione substituted by methyl groups at positions 4a and 8 and a methylidene group at position 3. Isolated from the aerial parts of Inula hupehensis, it exhibits anti-inflammatory activity.


HELENALIN

A sesquiterpene lactone that is 3,3a,4,4a,7a,8,9,9a-octahydroazuleno[6,5-b]furan-2,5-dione substituted by a hydroxy group at position 4, methyl groups at positions 4a and 8 and a methylidene group at position 3 (the 3aS,4S,4aR,7aR,8R,9aR stereoisomer).


name: 3-Methyl-2-(5-methylene-1,1-dioxo-3,4-dihydro-1,2-benzothiazepin-2-yl)butanoic acid methyl ester


name: STAT3_HUMAN Signal transducer and activator of transcription 3 (sprot)

description: A signal transducer and activator of transcription 3 that is encoded in the genome of human.


name: 1H-indazole-3-carboxylic acid methyl ester


name: PPBT_HUMAN Alkaline phosphatase, tissue-nonspecific isozyme (sprot)

description: An alkaline phosphatase, tissue-nonspecific isozyme that is encoded in the genome of human.


name: 4-{2-[(Thiophene-2-carbonyl)-amino]-ethylamino}-piperidine-1-carboxylic acid ethyl ester


name: ACM1_RAT Muscarinic acetylcholine receptor M1 (sprot)

description: A muscarinic acetylcholine receptor M1 that is encoded in the genome of rat.


name: 4-[2-(2-Chloro-benzoylamino)-ethylamino]-piperidine-1-carboxylic acid ethyl ester


name: 4-(2-benzamidoethylamino)-1-piperidinecarboxylic acid ethyl ester


name: NMT_CANAL Glycylpeptide N-tetradecanoyltransferase (sprot)

description: A glycylpeptide N-tetradecanoyltransferase 2 that is encoded in the genome of Candida albicans SC5314.


name: NMT1_HUMAN Glycylpeptide N-tetradecanoyltransferase 1 (sprot)

description: A glycylpeptide N-tetradecanoyltransferase 1 that is encoded in the genome of human.


name: OST1_YEAST Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 (sprot)

description: A dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 that is encoded in the genome of yeast.


name: S12A5_HUMAN Solute carrier family 12 member 5 (sprot)

description: A solute carrier family 12 member 5 that is encoded in the genome of human.


name: 2-Methyl-2H-pyrazole-3-carboxylic acid (4-phenyl-thiazol-2-ylcarbamoyl)-methyl ester


diflunisal

An organofluorine compound comprising salicylic acid having a 2,4-difluorophenyl group at the 5-position.


name: (2S)-2-[[(2S,3S)-6-bromo-4-keto-2-(3-methoxyphenyl)chroman-3-yl]oxycarbonylamino]-3-methyl-butyric acid methyl ester


name: [(Z)-2-(4-Bromo-benzoylamino)-3-phenyl-acryloylamino]-acetic acid benzyl ester


name: 5-nitro-2-[(phenylmethyl)amino]benzoic acid [2-(cyclohexylamino)-2-oxoethyl] ester


name: 1-[2-(4-Benzyl-piperidin-1-yl)-2-oxo-ethyl]-4-methyl-1,4-dihydro-pyrrolo[3,2-b]pyrrole-2-carboxylic acid ethyl ester


dafadine C

An N-acylpiperidine obtained by formal condensation of the carboxy group of 5-[(2,6-difluorophenoxy)methyl]-1,2-oxazole-3-carboxylic acid with the secondary amino group of 4-(pyridin-4-yl)piperidine.


name: 4-[2-[[(4-fluorophenyl)-oxomethyl]amino]ethylamino]-1-piperidinecarboxylic acid ethyl ester


name: 4-[2-[[(3-fluorophenyl)-oxomethyl]amino]ethylamino]-1-piperidinecarboxylic acid ethyl ester


name: 4-[2-[[(3,4-difluorophenyl)-oxomethyl]amino]ethylamino]-1-piperidinecarboxylic acid ethyl ester


name: 4-[2-(m-Anisoylamino)ethylamino]piperidine-1-carboxylic acid ethyl ester;2,2,2-trifluoroacetic acid


name: formic acid;(2S)-1-[(2S)-3-methyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]pyrrolidine-2-carboxylic acid benzyl ester


name: (2S)-1-[(2S)-2-[[(2S)-2-amino-1-oxopropyl]amino]-2-cyclohexyl-1-oxoethyl]-2-pyrrolidinecarboxylic acid (phenylmethyl) ester;2,2,2-trifluoroacetic acid


name: formic acid;(3S)-4-keto-3-[[(2S)-2-(methylamino)propanoyl]amino]-4-[(2S)-2-(tetralin-1-ylcarbamoyl)pyrrolidino]butyric acid methyl ester


name: formic acid;N-[(4S)-5-keto-4-[[(2S)-3-methyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]amino]-5-(tetralin-1-ylamino)pentyl]carbamic acid benzyl ester


name: formic acid;N-[(5S)-6-keto-5-[[(2S)-3-methyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]amino]-6-(tetralin-1-ylamino)hexyl]carbamic acid benzyl ester


name: TNF10_HUMAN Tumor necrosis factor ligand superfamily member 10 (sprot)

description: A tumor necrosis factor ligand superfamily member 10 that is encoded in the genome of human.


name: ACM4_RAT Muscarinic acetylcholine receptor M4 (sprot)

description: A muscarinic acetylcholine receptor M4 that is encoded in the genome of rat.


name: 3-(4-bromophenyl)-1H-pyrazole-5-carboxylic acid methyl ester


name: EPHA4_MOUSE Ephrin type-A receptor 4 (sprot)

description: An ephrin type-A receptor 4 that is encoded in the genome of mouse.


name: 5-Hydroxy-2-methyl-4-[morpholino(3-pyridyl)methyl]benzo[g]benzofuran-3-carboxylic acid ethyl ester


name: REV_HV1W2 Protein Rev (Fragment) (sprot)


name: MRP1_HUMAN Multidrug resistance-associated protein 1 (sprot)

description: A multidrug resistance-associated protein 1 that is encoded in the genome of human.


name: 2-[(5,5-dimethyl-6H-[1,2,4]triazolo[3,4-a]isoquinolin-3-yl)thio]acetic acid propan-2-yl ester


name: 3-[5-(4-Chloro-phenoxymethyl)-[1,3,4]oxadiazol-2-ylsulfanylmethyl]-4-methoxy-benzoic acid methyl ester


name: ({2-[5-(4-Methoxy-phenoxymethyl)-4-methyl-4H-[1,2,4]triazol-3-ylsulfanyl]-acetyl}-phenyl-amino)-acetic acid ethyl ester


triamcinolone

A C21-steroid hormone that is 1,4-pregnadiene-3,20-dione carrying four hydroxy substituents at positions 11beta, 16alpha, 17alpha and 21 as well as a fluoro substituent at position 9. Used in the form of its 16,17-acetonide to treat various skin infections.


name: 5-amino-1-(2-pyridinyl)-4-pyrazolecarboxylic acid ethyl ester


name: 2-[[1-oxo-2-(1H-1,2,4-triazol-5-ylthio)ethyl]amino]-4-thiophen-2-yl-3-thiophenecarboxylic acid ethyl ester


name: 3-methyl-4-oxo-1,5,6,7-tetrahydroindole-2-carboxylic acid (4-methylcyclohexyl) ester


name: 2-[2-[(5-Methyl-3-phenyl-isoxazole-4-carbonyl)amino]thiazol-4-yl]acetic acid ethyl ester


(-)-adrenaline

The R-enantiomer of adrenaline. It is a hormone secreted by the adrenal glands resulting in the 'fight-or-flight' response.


name: 5-Methyl-7-(3-pyridinyl)-1,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxylic acid ethyl ester


name: 4-Amino-3-cyclohexylcarbamoyl-isothiazole-5-carboxylic acid 1-tert-butylcarbamoyl-ethyl ester


name: carbamothioic acid S-[2-(2-methoxyanilino)-2-oxoethyl] ester


name: 4-(5-methyl-2-furanyl)-2-[[1-oxo-2-(1H-1,2,4-triazol-5-ylthio)ethyl]amino]-3-thiophenecarboxylic acid ethyl ester


name: (Z)-3-(4-hydroxyanilino)-2-nitro-acrylic acid methyl ester


name: 1,2,3,4-tetrahydroacridine-9-carboxylic acid [2-(3-chloro-4-methoxyanilino)-2-oxoethyl] ester


name: Benzoic acid 4-bromo-2-[(5-methyl-2H-pyrazole-3-carbonyl)-hydrazonomethyl]-phenyl ester


name: 2-[[cyclohexyl(oxo)methyl]amino]-4-(3-nitrophenyl)-3-thiophenecarboxylic acid ethyl ester


name: N-[4-(4-ethylphenyl)-2-thiazolyl]carbamic acid phenyl ester


name: 4-{2-[4-(3-Methoxy-phenylthiocarbamoyl)-piperazin-1-yl]-2-oxo-acetylamino}-benzoic acid methyl ester


name: 2-(4-acetoxybenzylidene)-3-keto-7-methyl-5-[(E)-styryl]-5H-thiazolo[3,2-a]pyrimidine-6-carboxylic acid ethyl ester


name: 2-(4-Benzylpiperazino)-2-[(2-chlorophenyl)hydrazono]acetic acid ethyl ester


name: carbamimidothioic acid (2-chlorophenyl)methyl ester


name: 1-Furan-2-ylmethyl-5-oxo-pyrrolidine-3-carboxylic acid 2-[4-(furan-2-carbonyloxy)-phenyl]-2-oxo-ethyl ester


name: Acetic acid [2-phenyl-4-(2-pyridinyliminomethyl)-5-oxazolyl] ester


pentamidine

A diether consisting of pentane-1,5-diol in which both hydroxyl hydrogens have been replaced by 4-amidinophenyl groups. A  trypanocidal drug that is used for treatment of cutaneous leishmaniasis and Chagas disease.


name: Furan-2-carboxylic acid 3-[(5-methyl-2H-pyrazole-3-carbonyl)-hydrazonomethyl]-phenyl ester


name: 3,4,5-trimethoxybenzoic acid [(3,5-dimethyl-4-oxo-1-cyclohexa-2,5-dienylidene)amino] ester


name: PTN7_HUMAN Tyrosine-protein phosphatase non-receptor type 7 (sprot)

description: A tyrosine-protein phosphatase non-receptor type 7 that is encoded in the genome of human.


name: HSP7C_HUMAN Heat shock cognate 71 kDa protein (sprot)

description: A heat shock cognate 71 kDa protein that is encoded in the genome of human.


name: 2-methyl-5-[(2-oxo-1H-benzo[cd]indol-6-yl)sulfonylamino]-3-benzofurancarboxylic acid butyl ester


name: 2-{2-[1-(3,4-Dimethyl-phenyl)-1H-tetrazol-5-ylsulfanyl]-acetylamino}-4-methyl-thiazole-5-carboxylic acid ethyl ester


name: NCOA2_HUMAN Nuclear receptor coactivator 2 (sprot)

description: A nuclear receptor coactivator 2 that is encoded in the genome of human.


name: GSTM1_HUMAN Glutathione S-transferase Mu 1 (sprot)

description: A glutathione S-transferase mu 1 that is encoded in the genome of human.


name: B2L10_HUMAN Bcl-2-like protein 10 (sprot)

description: A Bcl-2-like protein 10 that is encoded in the genome of human.


name: B2CL2_HUMAN Bcl-2-like protein 2 (sprot)

description: A protein that is a translation product of any of the following genes in human: BCL2L2, or a readthrough of the BCL2L2-PABPN1 genes.


name: NCOA3_HUMAN Nuclear receptor coactivator 3 (sprot)

description: A nuclear receptor coactivator 3 that is encoded in the genome of human.


name: {(4-Fluoro-phenyl)-[2-(8-methoxy-5H-[1,2,4]triazino[5,6-b]indol-3-ylsulfanyl)-acetyl]-amino}-acetic acid ethyl ester


name: 4-Amino-3-cyclohexylcarbamoyl-isothiazole-5-carboxylic acid cyclohexylcarbamoylmethyl ester


digoxin

A  cardenolide glycoside that is digitoxin beta-hydroxylated at C-12. A cardiac glycoside extracted from the foxglove plant, Digitalis lanata, it is used to control ventricular rate in atrial fibrillation and in the management of congestive heart failure with atrial fibrillation, but the margin between toxic and therapeutic doses is small.


ouabain

A steroid hormone that is a multi-hydroxylated alpha-L-rhamnosyl cardenoloide. It binds to and inhibits the plasma membrane Na(+)/K(+)-ATPase (sodium pump). It has been isolated naturally from Strophanthus gratus.


digitoxin

A cardenolide glycoside in which the 3beta-hydroxy group of digitoxigenin carries a 2,6-dideoxy-beta-D-ribo-hexopyranosyl-(1->4)-2,6-dideoxy-beta-D-ribo-hexopyranosyl-(1->4)-2,6-dideoxy-beta-D-ribo-hexopyranosyl trisaccharide chain.


name: Benzoic acid [2-(1,3-diketo-5-methyl-3a,4,5,6,7,7a-hexahydroisoindol-2-yl)phenyl] ester


name: E2AK3_HUMAN Eukaryotic translation initiation factor 2-alpha kinase 3 (sprot)

description: A eukaryotic translation initiation factor 2-alpha kinase 3 that is encoded in the genome of human.


name: TERA_HUMAN Transitional endoplasmic reticulum ATPase (sprot)

description: A transitional endoplasmic reticulum ATPase that is encoded in the genome of human.


AMENTOFLAVONE

A biflavonoid that is obtained by oxidative coupling of two molecules of apigenin resulting in a bond between positions C-3 of the hydroxyphenyl ring and C-8 of the chromene ring.  A natural product found  particularly in Ginkgo biloba and Hypericum perforatum.


MCLN3_HUMAN Mucolipin-3 (sprot)

A mucolipin-3 that is encoded in the genome of human.


arecoline

A tetrahydropyridine that is 1,2,5,6-tetrahydropyridine with a methyl group at position 1, and a methoxycarbonyl group at position 3. An alkaloid found in the areca nut, it acts as an agonist of muscarinic acetylcholine.


name: 5-hydroxy-2-[[(4-methylphenyl)thio]methyl]-3-benzofurancarboxylic acid ethyl ester


PMM2_HUMAN Phosphomannomutase 2 (sprot)

A phosphomannomutase 2 that is encoded in the genome of human.


name: PHOP1_HUMAN Phosphoethanolamine/phosphocholine phosphatase (sprot)

description: A phosphoethanolamine/phosphocholine phosphatase that is encoded in the genome of human.


name: 4-[2-(cyclohexylamino)-2-oxo-1-[(1-oxo-2-thiophen-2-ylethyl)-(phenylmethyl)amino]ethyl]benzoic acid methyl ester


name: 3-[[oxo(2-quinoxalinyl)methyl]amino]benzoic acid ethyl ester


name: [(S)-2-Phenyl-1-(5-o-tolylmethanesulfonyl-[1,3,4]oxadiazol-2-yl)-ethyl]-carbamic acid tert-butyl ester


name: [(S)-2-Phenyl-1-(5-m-tolylmethanesulfonyl-[1,3,4]oxadiazol-2-yl)-ethyl]-carbamic acid tert-butyl ester


name: ACM2_HUMAN Muscarinic acetylcholine receptor M2 (sprot)

description: A muscarinic acetylcholine receptor M2 that is encoded in the genome of human.


name: 4-Chloro-benzoic acid 2,6-dibromo-4-(morpholine-4-carbothioyl)-phenyl ester


name: (4-{[4-(Benzyl-methanesulfonyl-amino)-benzoyl]-hydrazonomethyl}-phenoxy)-acetic acid methyl ester


CHRYSOERIOL

The 3'-O-methyl derivative of luteolin.


name: RGS8_HUMAN Regulator of G-protein signaling 8 (sprot)

description: A regulator of G-protein signaling 8 that is encoded in the genome of human.


dithiazanine

A cationic C3-cyanine dye with 3-ethylbenzothiazol-2-yl groups at both ends.


deferoxamine

An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.


NOCARDAMINE

A cyclic hydroxamic acid siderophore that is produced by several bacterial species and exhibits antitumour activity.


name: RGS7_HUMAN Regulator of G-protein signaling 7 (sprot)

description: A regulator of G-protein signaling 7 that is encoded in the genome of human.