L-amino acid transport

description: The directed movement of L-enantiomer amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


name: regulation of mammary gland epithelial cell proliferation

category: biolink:BiologicalProcess biolink:Occurrent biolink:OntologyClass biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: Any process that modulates the frequency, rate or extent of mammary gland epithelial cell proliferation.


name: epithelial cell differentiation involved in mammary gland alveolus development

description: The process in which a relatively unspecialized epithelial cell becomes a more specialized epithelial cell of the mammary gland alveolus.


superior olivary complex

category: biolink:AnatomicalEntity biolink:PhysicalEssence biolink:OrganismalEntity biolink:SubjectOfInvestigation biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: A collection of brainstem nuclei that functions in multiple aspects of hearing and is an important component of the ascending and descending auditory pathways of the auditory system.


hematopoietic system

description: Anatomical system that is involved in the production of hematopoietic cells.


red nucleus

description: Large round nucleus located in the midbrain tegmentum, consisting of a magnocellular and parvicellular portion in most species studied.


rhombomere 3 lateral wall

description: A rhombomere lateral wall that is part of a rhombomere 3.


lipase activator activity

category: biolink:MolecularActivity biolink:Occurrent biolink:OntologyClass biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: Binds to and increases the activity of a lipase, an enzyme that catalyzes of the hydrolysis of a lipid.


description: The myristoylation of the N-terminal glycine of proteins to form the derivative N-myristoyl-glycine.


N-terminal protein myristoylation

description: The covalent attachment of a myristoyl group to the N-terminal amino acid residue of a protein.


name: positive regulation of high voltage-gated calcium channel activity

description: Any process that activates or increases the frequency, rate or extent of high voltage-gated calcium channel activity.


name: voltage-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential

description: Any voltage-gated ion channel activity that is involved in regulation of postsynaptic membrane potential.


hormone binding

description: Binding to an hormone, a naturally occurring substance secreted by specialized cells that affect the metabolism or behavior of cells possessing functional receptors for the hormone. Hormones may be produced by the same, or different, cell as express the receptor.


name: chondroitin sulfate proteoglycan binding

description: Binding to a chondroitin sulfate proteoglycan, any proteoglycan containing chondroitin sulfate as the glycosaminoglycan carbohydrate unit.


name: CSPG2_MOUSE Versican core protein (sprot)

description: A versican core protein that is encoded in the genome of mouse.


regulation of immune system process

description: Any process that modulates the frequency, rate, or extent of an immune system process.


olfactory receptor activity

description: Combining with an odorant and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity in response to detection of smell.


mitochondrion distribution

description: Any process that establishes the spatial arrangement of mitochondria between and within cells.


name: regulation of CD8-positive, alpha-beta T cell differentiation

description: Any process that modulates the frequency, rate, or extent of CD8-positive, alpha-beta T cell differentiation.


name: kidney proximal convoluted tubule epithelial cell

category: biolink:Cell biolink:AnatomicalEntity biolink:PhysicalEssence biolink:OrganismalEntity biolink:SubjectOfInvestigation biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: Any epithelial cell of proximal tubule that is part of some proximal convoluted tubule.


name: regulation of guanylate cyclase activity

description: Any process that modulates the frequency, rate or extent of guanylate cyclase activity.


guanylate cyclase regulator activity

description: Modulates the activity of guanylate cyclase.


name: calcium sensitive guanylate cyclase activator activity

description: Binds to and increases the activity of guanylate cyclase in response to a change in calcium ion concentration.


name: EMAL4_HUMAN Echinoderm microtubule-associated protein-like 4 (sprot)

description: An echinoderm microtubule-associated protein-like 4 that is encoded in the genome of human.


exonuclease activity

description: Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 3' or 5' end.


flap endonuclease activity

description: Catalysis of the cleavage of a flap structure in DNA, but not other DNA structures; processes the ends of Okazaki fragments in lagging strand DNA synthesis.


manganese ion binding

description: Binding to a manganese ion (Mn).


name: mesenchymal stem cell maintenance involved in nephron morphogenesis

description: The process in which an organism retains a population of mesenchymal stem cells that contributes to the shaping of a nephron. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells.


adiponectin-activated signaling pathway

category: biolink:Pathway biolink:OntologyClass biolink:BiologicalProcess biolink:Occurrent biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: The series of molecular signals initiated by adiponectin binding to its receptor on the surface of a cell, and ending with the regulation of a downstream cellular process, e.g. transcription.


name: corticotrophin-releasing factor receptor activity

description: Combining with the corticotrophin-releasing factor family of ligands, including the urocortins, to initiate a change in cell activity.


name: planar cell polarity pathway involved in cardiac muscle tissue morphogenesis

description: The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity that contributes to the shaping of the cardiac muscle tissue.


name: SUN domain-containing protein 1 isoform m5 (mouse)

description: A SUN domain-containing protein 1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9D666-5.


cellular heat acclimation

description: Any process that increases heat tolerance of a cell in response to high temperatures.


cardiac left ventricle morphogenesis

description: The process in which the left cardiac ventricle is generated and organized.


fibroblast growth factor production

description: The appearance of a fibroblast growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


name: positive regulation of fibroblast growth factor production

description: Any process that increases the rate, frequency or extent of the appearance of a fibroblast growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


name: regulation of hair follicle cell proliferation

description: Any process that modulates the frequency, rate or extent of hair follicle cell proliferation.


positive regulation of cell maturation

description: Any process that activates or increases the frequency, rate or extent of cell maturation.


activin binding

description: Binding to activin, a dimer of inhibin-beta subunits.


sperm ejaculation

description: The expulsion of seminal fluid, thick white fluid containing spermatozoa, from the male genital tract.


activin receptor binding

description: Binding to an activin receptor.


name: INHBA_MOUSE Inhibin beta A chain (sprot)

description: An activin/inhibin beta A chain that is encoded in the genome of mouse.


response to peptide hormone

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide hormone stimulus. A peptide hormone is any of a class of peptides that are secreted into the blood stream and have endocrine functions in living animals.


name: negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator

description: Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator.


name: negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress

description: Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to osmotic stress.


determination of bilateral symmetry

description: The establishment of an organism's body plan or part of an organism with respect to a single longitudinal plane. The pattern can either be symmetric, such that the halves are mirror images, or asymmetric where the pattern deviates from this symmetry.


myosin heavy chain binding

description: Binding to a heavy chain of a myosin complex.


MYH6_MOUSE Myosin-6 (sprot)

A myosin-6 that is encoded in the genome of mouse.


name: MYO19_MOUSE Unconventional myosin-XIX (sprot)

description: A myosin-XIX that is encoded in the genome of mouse.


name: PTPRF_MOUSE Receptor-type tyrosine-protein phosphatase F (sprot)

description: A receptor-type tyrosine-protein phosphatase F that is encoded in the genome of mouse.


name: DUS3_MOUSE Dual specificity protein phosphatase 3 (sprot)

description: A dual specificity protein phosphatase 3 that is encoded in the genome of mouse.


thioether S-methyltransferase activity

description: Catalysis of the reaction: S-adenosyl-L-methionine(1+) + dimethyl sulfide = S-adenosyl-L-homocysteine + trimethylsulfonium.


vitamin E biosynthetic process

description: The chemical reactions and pathways resulting in the formation of vitamin E, tocopherol, which includes a series of eight structurally similar compounds. Alpha-tocopherol is the most active form in humans and is a powerful biological antioxidant.


name: negative regulation of post-translational protein modification

description: Any process that stops, prevents or reduces the frequency, rate or extent of post-translational protein modification.


name: positive regulation of reciprocal meiotic recombination

description: Any process that increases the frequency, rate or extent of recombination during meiosis. Reciprocal meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate.


melatonin receptor activity

description: Combining with melatonin, N-acetyl-5-methoxytryptamine, to initiate a change in cell activity. Melatonin is a neuroendocrine substance that stimulates the aggregation of melanosomes in melanophores, thus lightening the skin.


prostaglandin J receptor activity

description: Combining with prostaglandin J (PGJ(2)), a metabolite of prostaglandin D (PGD(2)) to initiate a change in cell activity.


prostaglandin D receptor activity

description: Combining with prostaglandin D (PGD(2)) to initiate a change in cell activity.


name: cellular response to prostaglandin D stimulus

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin D stimulus.


name: negative regulation of type B pancreatic cell apoptotic process

description: Any process that stops, prevents or reduces the frequency, rate or extent of type B pancreatic cell apoptotic process.


name: negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway

description: Any process that stops, prevents or reduces the frequency, rate or extent of an endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway.


name: positive regulation of type B pancreatic cell apoptotic process

description: Any process that activates or increases the frequency, rate or extent of type B pancreatic cell apoptotic process.


name: regulation of exocytic insertion of neurotransmitter receptor to postsynaptic membrane

description: Any process that modulates the frequency, rate or extent of exocytic fusion of neurotransmitter receptor containing vesicles into the postsynaptic membrane.


dynein intermediate chain binding

description: Binding to an intermediate chain of the dynein complex.


dynactin binding

description: Binding to a dynactin complex; a large protein complex that activates dynein-based motor activity.


name: single-celled organism vegetative growth phase

description: A phase of population growth during which single celled organisms reproduce by budding, fission, or other asexual methods.


actomyosin structure organization

description: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures containing both actin and myosin or paramyosin. The myosin may be organized into filaments.


name: positive regulation of peptidyl-tyrosine autophosphorylation

description: Any process that activates or increases the frequency, rate or extent of peptidyl-tyrosine autophosphorylation.


name: epithelial cell differentiation involved in salivary gland development

description: The process in which a relatively unspecialized cell acquire specialized structural and/or functional features of an epithelial cell of the salivary gland.


BH4 domain binding

description: Binding to a BH4 protein domain, present in Bcl-2 family members. All anti-apoptotic proteins contain BH1 and BH2 domains; some also contain an additional N-terminal BH4 domain, which is almost never seen in pro-apoptotic proteins. Loss of the BH4 domain can diminish or abrogate anti-apoptotic function or even impart outright death-promoting properties to the protein.


neural fold elevation formation

description: The process in which the lateral borders of the neural plate begin to migrate upwards to form the neural folds, caused by the proliferation of the underlying mesoderm.


name: heat shock protein HSP 90-alpha, initiator methionine removed non-ubiquitinated 1 (mouse)

description: A heat shock protein HSP 90-alpha, initiator methionine removed form in mouse that lacks cross-linking to K63-linked polyubiquitin on one or more Lys residues by Hectd1.


delta-catenin binding

description: Binding to the delta subunit of the catenin complex.


name: regulation of protein localization to cell surface

description: Any process that modulates the frequency, rate or extent of protein localization to the cell surface.


name: positive regulation of protein O-linked glycosylation

description: Any process that activates or increases the frequency, rate or extent of protein O-linked glycosylation.


name: regulation of defense response to virus by host

description: Any host process that modulates the frequency, rate, or extent of the antiviral response of a host cell or organism.


CD8-positive, alpha-beta memory T cell

description: A CD8-positive, alpha-beta T cell that has differentiated into a memory T cell.


name: positive regulation of pancreatic amylase secretion

description: Any process that activates or increases the frequency, rate or extent of pancreatic amylase secretion.


spine apparatus membrane

category: biolink:CellularComponent biolink:AnatomicalEntity biolink:PhysicalEssence biolink:OrganismalEntity biolink:SubjectOfInvestigation biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: The lipid bilayer surrounding the spine apparatus.


name: postsynaptic recycling endosome membrane

description: The lipid bilayer surrounding a postsynaptic recycling endosome.


name: extrinsic component of postsynaptic early endosome membrane

description: The component of the postsynaptic early endosome membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.


postsynaptic endocytic zone membrane

description: The region of the postsynaptic membrane that is part of the postsynaptic endocytic zone. This region of membrane is associated with stable clathrin puncta.


postsynaptic septin cytoskeleton

description: The portion of the septin cytoskeleton contained within the postsynapse.


presynaptic actin cytoskeleton

description: The actin cytoskeleton that is part of a presynapse.


postsynaptic endosome membrane

description: The lipid bilayer surrounding a postsynaptic endosome.


name: trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission

description: Cell-cell signaling between presynapse and postsynapse, mediated by transynaptic protein complexes, that modulates the synaptic transmission properties of the synapse.


name: postsynaptic dense core vesicle exocytosis

description: The secretion of molecules (e.g. neuropeptides, insulin-related peptides or neuromodulators such as serotonin and dopamine) contained within a postsynaptic dense core vesicle by fusion of the granule with the plasma membrane of the postsynapse in response to increased cytosolic calcium levels.


name: regulation of recycling endosome localization within postsynapse

description: Any process that modulates the frequency, rate or extent of transport or maintenance of location of a postsynaptic recycling endosome within the postsynapse.


name: regulation of neurotransmitter receptor transport, endosome to postsynaptic membrane

description: Any process that modulates the frequency, rate or extent of the directed movement of neurotransmitter receptor from the postsynaptic endosome to the postsynaptic membrane in transport vesicles.


name: maintenance of postsynaptic specialization structure

description: A process which maintains the organization and the arrangement of proteins in the presynaptic specialization.


synaptic vesicle recycling via endosome

description: Synaptic vesicle recycling where vesicles endocytosed via clathrin-coated pits re-acidify and refill with neurotransmitters after passing through an endosomal intermediate.


name: neurotransmitter receptor transport, endosome to plasma membrane

description: The directed movement of neurotransmitter receptor from the endosome to the plasma membrane in transport vesicles.


name: neurotransmitter receptor transport to postsynaptic membrane

description: The directed movement of neurotransmitter receptor to the postsynaptic membrane in transport vesicles.


name: establishment of endoplasmic reticulum localization to postsynapse

description: The directed movement of endoplasmic reticulum into a postsynaptic compartment such as a dendritic spine.


name: retrograde trans-synaptic signaling by nitric oxide, modulating synaptic transmission

description: Modulation of synaptic transmission by cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by nitric oxide.


name: calcium ion binding involved in regulation of postsynaptic cytosolic calcium ion concentration

description: The directed change of free calcium ion concentration in the postsynaptic cytosol via the reversible binding of calcium ions to calcium-binding proteins in the cytosol thereby modulating the spatial and temporal dynamics of changes in postsynaptic cytosolic calcium concentrations.


name: postsynaptic neurotransmitter receptor diffusion trapping

description: The process by which diffusing neurotransmitter receptor becomes trapped at the postsynaptic specialization membrane. This is typically due to interaction with components of the post-synaptic specialization.


postsynaptic membrane assembly

description: The aggregation, arrangement and bonding together of a set of components to form a postsynaptic membrane, a specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft).


name: regulation of translation at postsynapse

description: Any process that regulates translation occurring at the postsynapse.


name: regulation of synaptic signaling by nitric oxide

description: Any process that modulates the frequency, rate or extent of synaptic signaling by nitric oxide.


description: A process that results in the assembly, arrangement of constituent parts, or disassembly of a postsynaptic specialization, a structure that lies adjacent to the cytoplasmic face of the postsynaptic membrane.


name: regulation of postsynaptic neurotransmitter receptor diffusion trapping

description: Any process that modulates the frequency, rate or extent of postsynaptic neurotransmitter receptor diffusion trapping.


presynapse to nucleus signaling pathway

description: The series of molecular signals that conveys information from the presynapse to the nucleus via cytoskeletal transport of a protein from a presynapse to the component to the nucleus where it affects biochemical processes that occur in the nucleus (e.g DNA transcription, mRNA splicing, or DNA/histone modifications).


RNA polyadenylation at postsynapse

description: A polyadenylation event (the enzymatic addition of a sequence of adenylyl residues at the 3' end of an RNA molecule) that takes place at a postsynapse.


presynaptic signal transduction

description: Signal transduction in which the initial step occurs in a presynapse.


name: regulation of modification of synapse structure, modulating synaptic transmission

description: Any process that regulates the modification of synaptic structure and as a result regulates synaptic transmission.


name: neurotransmitter receptor transport postsynaptic membrane to endosome

description: Vesicle-mediated transport of a neurotransmitter receptor complex from the postsynaptic membrane to the postsynaptic early endosome.


postsynaptic endocytosis

description: A vesicle-mediated transport process in which the postsynapse take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle.


postsynaptic cytoskeleton organization

description: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising cytoskeletal filaments and their associated proteins in the postsynaptic cytoskeleton.


presynaptic cytoskeleton organization

description: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures and their associated proteins in the presynaptic cytoskeleton.


name: regulation of protein catabolic process at presynapse, modulating synaptic transmission

description: Any process that modulates synaptic transmission by regulating a catabolic process occurring at a presynapse.


name: protein catabolic process, modulating synaptic transmission

description: Any protein degradation process, occurring at a presynapse, that regulates synaptic transmission.


name: NPTX1_HUMAN Neuronal pentraxin-1 (sprot)

description: A neuronal pentraxin-1 that is encoded in the genome of human.


name: NPTX2_HUMAN Neuronal pentraxin-2 (sprot)

description: A neuronal pentraxin-2 that is encoded in the genome of human.


name: IRPL2_HUMAN X-linked interleukin-1 receptor accessory protein-like 2 (sprot)

description: An X-linked interleukin-1 receptor accessory protein-like 2 that is encoded in the genome of human.


name: CCG5_HUMAN Voltage-dependent calcium channel gamma-5 subunit (sprot)

description: A voltage-dependent calcium channel gamma-5 subunit that is encoded in the genome of human.


ITB3_HUMAN Integrin beta-3 (sprot)

An integrin beta-3 that is encoded in the genome of human.


name: SLIK1_HUMAN SLIT and NTRK-like protein 1 (sprot)

description: A SLIT and NTRK-like protein 1 that is encoded in the genome of human.


name: SLIK2_HUMAN SLIT and NTRK-like protein 2 (sprot)

description: A SLIT and NTRK-like protein 2 that is encoded in the genome of human.


name: SLIK4_HUMAN SLIT and NTRK-like protein 4 (sprot)

description: A SLIT and NTRK-like protein 4 that is encoded in the genome of human.


name: SPTB1_HUMAN Spectrin beta chain, erythrocytic (sprot)

description: A spectrin beta chain, erythrocytic that is encoded in the genome of human.


SNX27_HUMAN Sorting nexin-27 (sprot)

A sorting nexin-27 that is encoded in the genome of human.


name: CLAP2_HUMAN CLIP-associating protein 2 (sprot)

description: A CLIP-associating protein 2 that is encoded in the genome of human.


name: apoptosis regulator BAX isoform Alpha (mouse)

description: An apoptosis regulator BAX isoform 1 that is encoded in the genome of mouse.


name: JIP4_HUMAN C-Jun-amino-terminal kinase-interacting protein 4 (sprot)

description: A C-Jun-amino-terminal kinase-interacting protein 4 that is encoded in the genome of human.


name: CDON_HUMAN Cell adhesion molecule-related/down-regulated by oncogenes (sprot)

description: A cell adhesion molecule-related/down-regulated by oncogenes that is encoded in the genome of human.


brother of CDO isoform h1 (human)

A brother of CDO (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9BWV1-1.


name: BNIP2_HUMAN BCL2/adenovirus E1B 19 kDa protein-interacting protein 2 (sprot)

description: A BCL2/adenovirus E1B 19 kDa protein-interacting protein 2 that is encoded in the genome of human.


name: cell-cell adhesion involved in neuronal-glial interactions involved in cerebral cortex radial glia guided migration

description: The interaction between two cells that modulates the association of a neuronal cell and a glial cell involved in glial-mediated radial cell migration in the cerebral cortex.


name: positive regulation of small GTPase mediated signal transduction

description: Any process that activates or increases the frequency, rate or extent of small GTPase mediated signal transduction.


mast cell activation

description: The change in morphology and behavior of a mast cell resulting from exposure to a cytokine, chemokine, soluble factor, or to (at least in mammals) an antigen which the mast cell has specifically bound via IgE bound to Fc-epsilonRI receptors.


response to interleukin-15

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-15 stimulus.


name: development of secondary male sexual characteristics

description: The process whose specific outcome is the progression of the secondary male sexual characteristics over time, from their formation to the mature structures. In male humans, these include growth of axillary, chest, and pubic hair, voice changes, and testicular/penile enlargement. Development occurs in response to sex hormone secretion.


response to interleukin-2

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-2 stimulus.


response to interleukin-4

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-4 stimulus.


name: development of secondary female sexual characteristics

description: The process whose specific outcome is the progression of the secondary female sexual characteristics over time, from their formation to the mature structures. In female humans, these include growth of axillary and pubic hair, breast development and menstrual periods. Their development occurs in response to sex hormone secretion.


mast cell migration

description: The movement of a mast cell within or between different tissues and organs of the body.


name: ERBB4_MOUSE Receptor tyrosine-protein kinase erbB-4 (sprot)

description: A receptor tyrosine-protein kinase erbB-4 that is encoded in the genome of mouse.


protein localization to nuclear pore

description: A process in which a protein is transported to, or maintained in, a nuclear pore.


name: LAG3_HUMAN Lymphocyte activation gene 3 protein (sprot)

description: A lymphocyte activation gene 3 protein that is encoded in the genome of human.


name: DRA_HUMAN HLA class II histocompatibility antigen, DR alpha chain (sprot)

description: An MHC class II histocompatibility antigen alpha chain DRA that is encoded in the genome of human.


name: DQA2_HUMAN HLA class II histocompatibility antigen, DQ alpha 2 chain (sprot)

description: An MHC class II histocompatibility antigen alpha chain DQA2 that is encoded in the genome of human.


name: DQA1_HUMAN HLA class II histocompatibility antigen, DQ alpha 1 chain (sprot)

description: An MHC class II histocompatibility antigen alpha chain DQA1 that is encoded in the genome of human.


name: DRB1_HUMAN HLA class II histocompatibility antigen, DRB1 beta chain (sprot)

description: An MHC class II histocompatibility antigen beta chain DRB1 that is encoded in the genome of human.


name: DQB1_HUMAN HLA class II histocompatibility antigen, DQ beta 1 chain (sprot)

description: An MHC class II histocompatibility antigen beta chain DQB1 that is encoded in the genome of human.


name: DPB1_HUMAN HLA class II histocompatibility antigen, DP beta 1 chain (sprot)

description: An MHC class II histocompatibility antigen beta chain DPB1 that is encoded in the genome of human.


name: DQB2_HUMAN HLA class II histocompatibility antigen, DQ beta 2 chain (sprot)

description: An MHC class II histocompatibility antigen beta chain DQB2 that is encoded in the genome of human.


name: DRB4_HUMAN HLA class II histocompatibility antigen, DR beta 4 chain (sprot)

description: An MHC class II histocompatibility antigen beta chain DRB4 that is encoded in the genome of human.


name: DPA1_HUMAN HLA class II histocompatibility antigen, DP alpha 1 chain (sprot)

description: An MHC class II histocompatibility antigen alpha chain DPA1 that is encoded in the genome of human.


name: DRB3_HUMAN HLA class II histocompatibility antigen, DR beta 3 chain (sprot)

description: An MHC class II histocompatibility antigen beta chain DRB3 that is encoded in the genome of human.


name: DRB5_HUMAN HLA class II histocompatibility antigen, DR beta 5 chain (sprot)

description: An MHC class II histocompatibility antigen beta chain DRB5 that is encoded in the genome of human.


name: antigen processing and presentation of peptide antigen

description: The process in which an antigen-presenting cell expresses peptide antigen in association with an MHC protein complex on its cell surface, including proteolysis and transport steps for the peptide antigen both prior to and following assembly with the MHC protein complex. The peptide antigen is typically, but not always, processed from an endogenous or exogenous protein.


name: negative regulation of mast cell apoptotic process

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of mast cell apoptotic process.


name: positive regulation of mast cell proliferation

description: Any process that activates or increases the rate or extent of mast cell proliferation.


name: positive regulation of mast cell differentiation

description: Any process that increases the rate, frequency or extent of mast cell differentiation, the process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a mast cell. A mast cell is a cell that is found in almost all tissues containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation.


xanthophyll

A subclass of carotenoids consisting of the oxygenated carotenes.


name: cyclin-dependent protein kinase activity

description: Cyclin-dependent catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP.


R-SMAD binding

description: Binding to a receptor-regulated SMAD signaling protein.


name: DRD5_MACMU D(1B) dopamine receptor (Fragment) (sprot)


name: CAC1B_CHICK Voltage-dependent N-type calcium channel subunit alpha-1B (Fragment) (sprot)


dynein light intermediate chain binding

description: Binding to a light intermediate chain of the dynein complex.


name: IDLC_MOUSE Axonemal dynein light intermediate polypeptide 1 (sprot)

description: An axonemal dynein light intermediate polypeptide 1 that is encoded in the genome of mouse.


name: kidney loop of Henle medullary thick ascending limb epithelial cell

description: An epithelial cell that is part of some loop of Henle thick ascending limb segment located in the renal medulla.


name: solute carrier family 12 member 1 isoform A (mouse)

description: A solute carrier family 12 member 1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P55014-1.


glycerol transmembrane transport

description: The directed movement of glycerol across a membrane. Glycerol is 1,2,3-propanetriol, a sweet, hygroscopic, viscous liquid, widely distributed in nature as a constituent of many lipids.


gallbladder primordium

description: A sac-like cavity ventral to the liver, lying in the sub-mesodermal space and closed by a thin sheet of ectodermal cells, from which the future gall bladder develops.


taste receptor binding

description: Binding to a taste receptor.


7SK snRNA binding

description: Binding to a 7SK small nuclear RNA (7SK snRNA).


salivary gland glandular cell

description: Glandular cell of salivary gland. Example: Serous cells, mucous cells, cuboidal epithelial cells of the intercalated ducts, simple cuboidal epithelium of the striated ducts, epithelial cells of excretory ducts.


mucus secreting cell

description: Any secretory cell that is capable of some mucus secretion.


antibacterial peptide secretion

description: The regulated release of an antibacterial peptide from a cell or a tissue.


name: enterocyte of epithelium of small intestine

description: An enterocyte that is part of the epithelium of small intestine.


desmosome organization

description: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a desmosome. A desmosome is a patch-like intercellular junction found in vertebrate tissues, consisting of parallel zones of two cell membranes, separated by an space of 25-35 nm, and having dense fibrillar plaques in the subjacent cytoplasm.


name: cysteine-type endopeptidase activity involved in apoptotic signaling pathway

description: Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile, and contributing to the apoptotic signaling pathway.


description: The directed, sodium-independent, movement of prostaglandins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


dense core granule membrane

description: The lipid bilayer surrounding a dense core granule.


corticotropin secretion

description: The regulated release of corticotropin by a cell. Corticotropin hormone is a polypeptide hormone synthesized and secreted from corticotropes in the anterior lobe of the pituitary gland in response to corticotropin-releasing hormone (CRH) released by the hypothalamus.


iron import into cell

description: The directed movement of iron ions from outside of a cell into the cytoplasmic compartment. This may occur via transport across the plasma membrane or via endocytosis.


description: Catalysis of the reaction: CMP-N-acetyl-beta-neuraminate + 2 Fe(II)-[cytochrome b5] + 2 H+ + O2 = CMP-N-glycoloyl-beta-neuraminate + 2 Fe(III)-[cytochrome b5] + H2O.


description: The chemical reactions and pathways involving CMP-N-acetylneuraminate, a substance composed of 5-(acetylamino)-3,5-dideoxy-D-glycero-D-galacto-non-3-ulosonic acid in glycosidic linkage with cytidine monophosphate.


name: HES1_MOUSE Transcription factor HES-1 (sprot)

description: A transcription factor HES-1 that is encoded in the genome of mouse.


mitotic DNA damage checkpoint signaling

description: A signal transduction process involved in mitotic DNA damage checkpoint.


name: male germ-line stem cell asymmetric division

description: The self-renewing division of a germline stem cell in the male gonad, to produce a daughter stem cell and a daughter germ cell, which will divide to form the male gametes.


name: positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway

description: Any process that activates or increases the frequency, rate or extent of cysteine-type endopeptidase activity involved in apoptotic signaling pathway.


Cul2-RING ubiquitin ligase complex

description: A ubiquitin ligase complex in which a cullin from the Cul2 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by an elongin-BC adaptor and a SOCS/BC box protein.


negative regulation of growth

description: Any process that stops, prevents or reduces the rate or extent of growth, the increase in size or mass of all or part of an organism.


name: T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell

description: The change in morphology and behavior of a mature or immature T cell resulting from exposure to an antigen for which its T cell receptor is specific bound to an MHC molecule on an antigen presenting cell, leading to the initiation or perpetuation of an immune response.


name: negative regulation of macrophage antigen processing and presentation

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of macrophage antigen processing and presentation.


name: negative regulation of memory T cell differentiation

description: Any process that stops, prevents, or reduces the rate of memory T cell differentiation.


name: negative regulation of dendritic cell antigen processing and presentation

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of dendritic cell antigen processing and presentation.


name: DNJA1_MOUSE DnaJ homolog subfamily A member 1 (sprot)

description: A DnaJ homolog subfamily A member 1 that is encoded in the genome of mouse.


description: Catalysis of the reactions: D-myo-inositol 1,4,5-trisphosphate + H2O = myo-inositol 1,4-bisphosphate + phosphate, and 1D-myo-inositol 1,3,4,5-tetrakisphosphate + H2O = 1D-myo-inositol 1,3,4-trisphosphate + phosphate.


name: positive regulation of vascular permeability

description: Any process that increases the extent to which blood vessels can be pervaded by fluid.


name: vascular endothelial growth factor receptor 1 binding

description: Binding to a vascular endothelial growth factor receptor 1.


semaphorin receptor binding

description: Binding to a semaphorin receptor.


name: PLGF_HUMAN Placenta growth factor (sprot)

description: A placenta growth factor that is encoded in the genome of human.


name: ERBB3_MOUSE Receptor tyrosine-protein kinase erbB-3 (sprot)

description: A receptor tyrosine-protein kinase erbB-3 that is encoded in the genome of mouse.


name: epidermal growth factor receptor phosphorylated form (mouse)

description: An epidermal growth factor receptor (mouse) that includes at least one phosphorylated tyrosine. UniProtKB:Q01279, MOD:00048.


name: receptor tyrosine-protein kinase erbB-4 phosphotyrosine form (mouse)

description: A receptor tyrosine-protein kinase erbB-4 (mouse) that includes at least one phosphorylated tyrosine. UniProtKB:Q61527, MOD:00048.


name: receptor tyrosine-protein kinase erbB-2 phosphotyrosine form (mouse)

description: A receptor tyrosine-protein kinase erbB-2 (mouse) that includes at least one phosphorylated tyrosine. UniProtKB:P70424, MOD:00048.


name: regulation of Rho protein signal transduction

description: Any process that modulates the frequency, rate or extent of Rho protein signal transduction.


defense response to nematode

description: A response to protect an organism from a directly detected or perceived external threat from a nematode or nematodes, which results in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack.


arylesterase activity

description: Catalysis of the reaction: a phenyl acetate + H2O = a phenol + acetate.


name: phosphatidylcholine:ceramide cholinephosphotransferase 1 isoform 1 (mouse)

description: A phosphatidylcholine:ceramide cholinephosphotransferase 1 isoform 1 that is encoded in the genome of mouse.


name: metanephric nephron tubule epithelial cell differentiation

description: The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the metanephric nephron tubule as it progresses from its formation to the mature state.


name: negative regulation of cell adhesion involved in substrate-bound cell migration

description: The disassembly of adhesions at the front and rear of a migrating cell. At the leading edge, adhesion disassembly accompanies the formation of new protrusions; at the cell rear, it promotes tail retraction.


respiratory burst after phagocytosis

description: A phase of elevated metabolic activity, during which oxygen consumption increases, that occurs in neutrophils, monocytes, and macrophages shortly after phagocytosing material. An enhanced uptake of oxygen leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals, which play a part in microbiocidal activity.


name: negative regulation of hair follicle placode formation

description: Any process that decreases the rate, frequency, or extent of hair follicle placode formation, the developmental process in which a hair placode forms. An hair follicle placode is a thickening of the ectoderm that will give rise to the hair follicle bud.


fungiform papilla development

description: The progression of the fungiform papilla over time, from its formation to the mature structure. The fungiform papilla is a mushroom-shaped papilla of the tongue.


endopeptidase activator activity

description: Binds to and increases the activity of an endopeptidase.


name: antigen processing and presentation of exogenous antigen

description: The process in which an antigen-presenting cell expresses antigen (peptide or lipid) of exogenous origin on its cell surface in association with an MHC protein complex.


name: positive regulation of reactive oxygen species biosynthetic process

description: Any process that activates or increases the frequency, rate or extent of reactive oxygen species biosynthetic process.


triglyceride mobilization

description: The release of triglycerides, any triester of glycerol, from storage within cells or tissues, making them available for metabolism.


name: regulation of lipoprotein metabolic process

description: Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving lipoproteins, any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids.


cAMP metabolic process

description: The chemical reactions and pathways involving the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate).


flotillin complex

description: A protein complex that contains flotillin-1 and flotillin-2, and may contain associated proteins. Flotillins associate into membrane microdomains resembling caveolae.


regulation of actin binding

description: Any process that modulates the frequency, rate or extent of actin binding.


paracrine signaling

description: The transfer of information from one cell to another, where the signal travels from the signal-producing cell to the receiving cell by passive diffusion or bulk flow in intercellular fluid. The signaling cell and the receiving cell are usually in the vicinity of each other.


respiratory basal cell differentiation

description: The process in which a relatively unspecialized cell acquires the specialized features of a respiratory basal cell.


alveolar lamellar body

description: A specialized secretory organelle found in type II pneumocytes and involved in the synthesis, secretion, and reutilization of pulmonary surfactant.


name: negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis

description: Any process that reduces the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron.


branch elongation of an epithelium

description: The growth process in which a branch increases in length from its base to its tip.


nutrient reservoir activity

description: Functions in the storage of nutritious substrates.


name: central nervous system interneuron axonogenesis

description: Generation of a long process that carries efferent (outgoing) action potentials from the cell body towards target cells from a neuron located in the central nervous system whose axons remain within a single brain region.


adipose macrophage

description: A macrophage located in adipose tissue that is CD45-positive, CD11c-positive, and SIRPa-positive.


midgut development

description: The process whose specific outcome is the progression of the midgut over time, from its formation to the mature structure. The midgut is the middle part of the alimentary canal from the stomach, or entrance of the bile duct, to, or including, the large intestine.


name: entry of viral genome into host nucleus through nuclear pore complex via importin

description: Viral penetration into the host nucleus where the viral genome passes through the nuclear pore complex (NPC) using the cellular importin transport machinery.


stem cell fate specification

description: The process in which a cell becomes capable of differentiating autonomously into a stem cell in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed.


name: B2MVI1_LAMFL Epsin 1 (Fragment) (trembl)


name: AP2B1_HUMAN AP-2 complex subunit beta (sprot)

description: An AP-2 complex subunit beta that is encoded in the genome of human.


name: AP2S1_HUMAN AP-2 complex subunit sigma (sprot)

description: An AP-2 complex subunit sigma that is encoded in the genome of human.


name: AP2M1_HUMAN AP-2 complex subunit mu (sprot)

description: An AP-2 complex subunit mu that is encoded in the genome of human.


regulation of RNA metabolic process

description: Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving RNA.


UV protection

description: Any process in which an organism or cell protects itself from ultraviolet radiation (UV), which may also result in resistance to repeated exposure to UV.


name: planar cell polarity pathway involved in ventricular septum morphogenesis

description: The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity that contributes to the shaping of the ventricular septum.


name: negative regulation of substrate adhesion-dependent cell spreading

description: Any process that stops, prevents or reduces the frequency, rate or extent of substrate adhesion-dependent cell spreading.


name: prostaglandin E2 receptor EP3 subtype isoform Alpha (mouse)

description: A prostaglandin E2 receptor EP3 subtype isoform 1 that is encoded in the genome of mouse.


TSN7_HUMAN Tetraspanin-7 (sprot)

A tetraspanin-7 that is encoded in the genome of human.


CD48_HUMAN CD48 antigen (sprot)

A CD48 molecule that is encoded in the genome of human.


name: MERTK_HUMAN Tyrosine-protein kinase Mer (sprot)

description: A tyrosine-protein kinase Mer that is encoded in the genome of human.


name: JAM2_HUMAN Junctional adhesion molecule B (sprot)

description: A junctional adhesion molecule B that is encoded in the genome of human.


name: SELPL_HUMAN P-selectin glycoprotein ligand 1 (sprot)

description: A P-selectin glycoprotein ligand 1 that is encoded in the genome of human.


name: FCAMR_HUMAN High affinity immunoglobulin alpha and immunoglobulin mu Fc receptor (sprot)

description: A high affinity immunoglobulin alpha and immunoglobulin mu Fc receptor that is encoded in the genome of human.


name: SLAF5_HUMAN SLAM family member 5 (sprot)

description: A SLAM family member 5 that is encoded in the genome of human.


LYAM2_HUMAN E-selectin (sprot)

An E-selectin that is encoded in the genome of human.


name: C99L2_HUMAN CD99 antigen-like protein 2 (sprot)

description: A CD99 molecule-like protein 2 that is encoded in the genome of human.


name: CD2_HUMAN T-cell surface antigen CD2 (sprot)

description: A CD2 molecule that is encoded in the genome of human.


name: CD244_HUMAN Natural killer cell receptor 2B4 (sprot)

description: A natural killer cell receptor 2B4 that is encoded in the genome of human.


name: EPCAM_HUMAN Epithelial cell adhesion molecule (sprot)

description: An epithelial cell adhesion molecule that is encoded in the genome of human.


LEUK_HUMAN Leukosialin (sprot)

A leukosialin that is encoded in the genome of human.


name: SIRPG_HUMAN Signal-regulatory protein gamma (sprot)

description: A signal-regulatory protein gamma that is encoded in the genome of human.


GLPA_HUMAN Glycophorin-A (sprot)

A glycophorin-A that is encoded in the genome of human.


GLPC_HUMAN Glycophorin-C (sprot)

A glycophorin-C that is encoded in the genome of human.


GLPB_HUMAN Glycophorin-B (sprot)

A glycophorin-B that is encoded in the genome of human.


name: CEAM5_HUMAN Carcinoembryonic antigen-related cell adhesion molecule 5 (sprot)

description: A carcinoembryonic antigen-related cell adhesion molecule 5 that is encoded in the genome of human.


name: OMPC_NEIGO Outer membrane protein P.IIC (sprot)


name: OPAC_NEIGO Opacity protein opA50 (Fragment) (sprot)


name: OP28_NEIGO Opacity protein V28 (Fragment) (sprot)


name: PSG1_HUMAN Pregnancy-specific beta-1-glycoprotein 1 (sprot)

description: A pregnancy-specific beta-1-glycoprotein 1 that is encoded in the genome of human.


name: PSG2_HUMAN Pregnancy-specific beta-1-glycoprotein 2 (sprot)

description: A pregnancy-specific beta-1-glycoprotein 2 that is encoded in the genome of human.


name: EBA1_PLAFC Erythrocyte-binding antigen 175 (sprot)


name: PSG9_HUMAN Pregnancy-specific beta-1-glycoprotein 9 (sprot)

description: A pregnancy-specific beta-1-glycoprotein 9 that is encoded in the genome of human.


name: PSG4_HUMAN Pregnancy-specific beta-1-glycoprotein 4 (sprot)

description: A pregnancy-specific beta-1-glycoprotein 4 that is encoded in the genome of human.


name: PSG6_HUMAN Pregnancy-specific beta-1-glycoprotein 6 (sprot)

description: A pregnancy-specific beta-1-glycoprotein 6 that is encoded in the genome of human.


name: OPAB_NEIGO Opacity protein opA51 (Fragment) (sprot)


name: OPAG_NEIGO Opacity protein opA52 (Fragment) (sprot)


name: OPAA_NEIGO Opacity protein opA53 (Fragment) (sprot)


name: OPAI_NEIGO Opacity protein opA54 (sprot)


name: OPAE_NEIGO Opacity protein opA55 (Fragment) (sprot)


name: OPAF_NEIGO Opacity protein opA56 (Fragment) (sprot)


name: OPAK_NEIGO Opacity protein opA57 (Fragment) (sprot)


name: OPA68_NEIGO Opacity protein opA68 (Fragment) (sprot)


name: OPAJ_NEIGO Opacity protein opA58 (sprot)


name: OPAD_NEIGO Opacity protein opA59 (Fragment) (sprot)


name: OPAH_NEIGO Opacity protein opA60 (Fragment) (sprot)


name: OPA65_NEIGO Opacity protein opA65 (Fragment) (sprot)


name: OPA66_NEIGO Opacity protein opA66 (Fragment) (sprot)


name: OPA67_NEIGO Opacity protein opA67 (Fragment) (sprot)


name: PSG7_HUMAN Pregnancy-specific beta-1-glycoprotein 7 (sprot)

description: A pregnancy-specific beta-1-glycoprotein 7 that is encoded in the genome of human.


name: PSG5_HUMAN Pregnancy-specific beta-1-glycoprotein 5 (sprot)

description: A pregnancy-specific beta-1-glycoprotein 5 that is encoded in the genome of human.


name: PSG3_HUMAN Pregnancy-specific beta-1-glycoprotein 3 (sprot)

description: A pregnancy-specific beta-1-glycoprotein 3 that is encoded in the genome of human.


name: Q76NM5_PLAF7 Erythrocyte binding antigen-140 (trembl)


name: GSLG1_HUMAN Golgi apparatus protein 1 (sprot)

description: A Golgi apparatus protein 1 that is encoded in the genome of human.


name: ESAM_HUMAN Endothelial cell-selective adhesion molecule (sprot)

description: An endothelial cell-selective adhesion molecule that is encoded in the genome of human.


name: Q9U4X0_PLAFA Putative erythrocyte binding protein EBL-1 (Fragment) (trembl)


name: PSG11_HUMAN Pregnancy-specific beta-1-glycoprotein 11 (sprot)

description: A pregnancy-specific beta-1-glycoprotein 11 that is encoded in the genome of human.


name: PSG8_HUMAN Pregnancy-specific beta-1-glycoprotein 8 (sprot)

description: A pregnancy-specific beta-1-glycoprotein 8 that is encoded in the genome of human.


Mullerian tubercle

description: An elevation on the wall of the embryonic urogenital sinus where the Müllerian ducts enter.


N-acetylglucosamine metabolic process

description: The chemical reactions and pathways involving N-acetylglucosamine. The D isomer is a common structural unit of glycoproteins in plants, bacteria and animals; it is often the terminal sugar of an oligosaccharide group of a glycoprotein.


name: dosage compensation by inactivation of X chromosome

description: Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by heterochromatin formation leading to a global inactivation of all, or most of, the genes on one of the X-chromosomes in the XX sex.


mature gamma-delta T cell

description: A gamma-delta T cell that has a mature phenotype. These cells can be found in tissues and circulation where they express unique TCR repertoire depending on their location.


syntaxin binding

description: Binding to a syntaxin, a SNAP receptor involved in the docking of synaptic vesicles at the presynaptic zone of a synapse.


name: metanephric glomerular basement membrane development

description: The process whose specific outcome is the progression of the metanephric glomerular basement membrane over time, from its formation to the mature structure. The metanephric glomerular basement membrane is the basal laminal portion of the metanephric glomerulus which performs the actual filtration.


plasma membrane tubulation

description: A membrane tubulation process occurring in a plasma membrane.


name: negative regulation of apoptotic process involved in morphogenesis

description: Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in morphogenesis.


name: negative regulation of epithelial cell migration

description: Any process that stops, prevents, or reduces the frequency, rate or extent of epithelial cell migration.


ovarian cumulus expansion

description: Increase in size of the cumulus surrounding the oocyte including change in morphology due to proliferation and dispersion of cumulus cells.


(1->3)-beta-D-glucan binding

description: Binding to a (1->3)-beta-D-glucan.


name: trans-synaptic signaling by endocannabinoid, modulating synaptic transmission

description: Cell-cell signaling between presynapse and postsynapse, via the release and reception of endocannabinoid ligands, that modulates the synaptic transmission properties of the synapse.


name: extracellular matrix structural constituent conferring compression resistance

description: A constituent of the extracellular matrix that enables the matrix to resist compressive forces; often a proteoglycan.


TBB3_MOUSE Tubulin beta-3 chain (sprot)

A tubulin beta-3 chain that is encoded in the genome of mouse.


nephrogenic zone

description: Outer portion of the renal cortex. Site of formation of medullary and cortical elements.


name: positive regulation of inner ear receptor cell differentiation

description: Any process that activates or increases the frequency, rate or extent of inner ear receptor cell differentiation.


A 2-methylpentadecenoyl-CoA in which the double bond is located at position 2 (geochemistry not specified).


An unsaturated fatty acyl-CoA that results from the formal condensation of the thiol group of coenzyme A with the carboxy group of 2-docosenoic acid. The product of dehydrogenation of behenoyl-CoA


docosanoyl-CoA

A very long-chain fatty acyl-CoA that results from the formal condensation of the thiol group of coenzyme A with the carboxy group of docosanoic (behenic) acid.


A mono-unsaturated fatty acyl-CoA that results from the formal condensation of the thiol group of coenzyme A with the carboxy group of any 2-methylpentadecenoic acid.


name: ACPM_HUMAN Acyl carrier protein, mitochondrial (sprot)

description: An acyl carrier protein, mitochondrial that is encoded in the genome of human.


name: ABCA1_HUMAN Phospholipid-transporting ATPase ABCA1 (sprot)

description: A phospholipid-transporting ATPase ABCA1 that is encoded in the genome of human.


name: ANGL4_HUMAN Angiopoietin-related protein 4 (sprot)

description: An angiopoietin-related protein 4 that is encoded in the genome of human.


name: G0S2_HUMAN G0/G1 switch protein 2 (sprot)

description: A G0/G1 switch protein 2 that is encoded in the genome of human.


name: ACADM_HUMAN Medium-chain specific acyl-CoA dehydrogenase, mitochondrial (sprot)

description: A medium-chain specific acyl-CoA dehydrogenase, mitochondrial that is encoded in the genome of human.


name: PX11A_HUMAN Peroxisomal membrane protein 11A (sprot)

description: A peroxisomal membrane protein 11A that is encoded in the genome of human.


name: GRHL1_HUMAN Grainyhead-like protein 1 homolog (sprot)

description: A grainyhead-like protein 1 that is encoded in the genome of human.


name: ST2A1_HUMAN Sulfotransferase 2A1 (sprot)

description: A sulfotransferase 2A1 that is encoded in the genome of human.


name: MAOX_HUMAN NADP-dependent malic enzyme (sprot)

description: An NADP-dependent malic enzyme that is encoded in the genome of human.


name: ANKR1_HUMAN Ankyrin repeat domain-containing protein 1 (sprot)

description: An ankyrin repeat domain-containing protein 1 that is encoded in the genome of human.


name: FHL2_HUMAN Four and a half LIM domains protein 2 (sprot)

description: A four and a half LIM domains protein 2 that is encoded in the genome of human.


name: TNR21_HUMAN Tumor necrosis factor receptor superfamily member 21 (sprot)

description: A tumor necrosis factor receptor superfamily member 21 that is encoded in the genome of human.


APOA2_HUMAN Apolipoprotein A-II (sprot)

An apolipoprotein A-II that is encoded in the genome of human.


name: peroxisomal acyl-coenzyme A oxidase 1 isoform h1 (human)

description: A peroxisomal acyl-coenzyme A oxidase 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q15067-1.


name: positive regulation of MHC class I biosynthetic process

description: Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of MHC class I.


name: antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent

description: The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class Ib protein complex following intracellular transport via a TAP (transporter associated with antigen processing) pathway. The peptide is typically a fragment of a larger exogenous protein which has been degraded within the cell and is dependent on TAP transport from the cytosol to ER for association with the MHC class Ib molecule. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family.


name: antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent

description: The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class Ib protein complex following intracellular transport via a TAP (transporter associated with antigen processing) pathway. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell and is dependent on TAP transport from the cytosol to ER for association with the MHC class Ib molecule. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family.


name: positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway

description: Any process that activates or increases the frequency, rate or extent of an oxidative stress-induced intrinsic apoptotic signaling pathway.


name: regulation of MHC class I biosynthetic process

description: Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of MHC class I.


name: tumor protein p53-inducible nuclear protein 1 isoform 2 (mouse)

description: A tumor protein p53-inducible nuclear protein 1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9QXE4-2.


name: regulation of signal transduction by receptor internalization

description: Any process that modulates the frequency, rate or extent of signal transduction by the movement of a signaling receptor from the plasma membrane to the inside of the cell. Receptor internalization can have a positive or negative effect on a signaling pathway.


name: regulation of nerve growth factor receptor activity

description: Any process that modulates the frequency, rate or extent of the activity of the nerve growth factor (NGF) receptor.


mannosidase activity

description: Catalysis of the hydrolysis of mannosyl compounds, substances containing a group derived from a cyclic form of mannose or a mannose derivative.


name: hydrolase activity, hydrolyzing N-glycosyl compounds

description: Catalysis of the hydrolysis of any N-glycosyl bond.


blastocele

description: Fluid-filled central region of a blastocyst.


collagen type IV trimer

description: A collagen heterotrimer containing type IV alpha chains; [alpha1(IV)]2alpha2(IV) trimers are commonly observed, although more type IV alpha chains exist and may be present in type IV trimers; type IV collagen triple helices associate to form 3 dimensional nets within basement membranes.


chaperonin-containing T-complex

description: A multisubunit ring-shaped complex that mediates protein folding in the cytosol without a cofactor.


name: T-complex protein 1 subunit eta isoform 1 phosphorylated 1 (mouse)

description: A T-complex protein 1 subunit eta isoform 1 phosphorylated 1 in mouse. UniProtKB:P80313-1, Thr-57, MOD:00047|Ser-59, MOD:00046.


name: T-complex protein 1 subunit epsilon isoform 1 phosphorylated 1 (mouse)

description: A T-complex protein 1 subunit epsilon isoform 1 phosphorylated 1 in mouse. UniProtKB:P80316-1, Ser-270, MOD:00046.


inferior colliculus development

description: The process whose specific outcome is the progression of the inferior colliculus over time, from its formation to the mature structure. The inferior colliculus (IC) (Latin, lower hill) is the principal midbrain nucleus of the auditory pathway and receives input from several more peripheral brainstem nuclei in the auditory pathway, as well as inputs from the auditory cortex. The inferior colliculus has three subdivisions: the central nucleus (CIC), a dorsal cortex (DCIC) by which it is surrounded, and an external cortex (ICX) which is located laterally.


olfactory nerve development

description: The process whose specific outcome is the progression of the olfactory nerve over time, from its formation to the mature structure. The olfactory nerve is a collection of sensory nerve rootlets that extend down from the olfactory bulb to the olfactory mucosa of the upper parts of the nasal cavity. This nerve conducts odor information to the brainstem.


name: regulation of synapse structure or activity

description: Any process that modulates the physical form or the activity of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell).


sialic acid binding

description: Binding to a sialic acid, a N- or O- substituted derivative of neuraminic acid, a nine carbon monosaccharide. Sialic acids often occur in polysaccharides, glycoproteins, and glycolipids in animals and bacteria.


anterior neuropore closure

description: The joining together of the neural folds of the rostral opening of the neural tube. The anterior neuropore appears before the process of neural tube closure is complete.


negative regulation of wound healing

description: Any process that decreases the rate, frequency, or extent of the series of events that restore integrity to a damaged tissue, following an injury.


name: regulation of synaptic vesicle recycling

description: Any process that modulates the frequency, rate or extent of synaptic vesicle recycling.


name: negative regulation of molecular function

description: Any process that stops or reduces the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding.


cervix development

description: The reproductive developmental process whose specific outcome is the progression of the cervix over time, from its formation to the mature structure.


name: Q99232_MOUSE Carcinoembryonic antigen family member protein (trembl)

description: A carcinoembryonic antigen-related cell adhesion molecule 1 sequence variant CEACAM1b (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q99232. This form contains the two copies of the Ig domain and is the version with shorter cytoplasmic tail.


cell killing

description: Any process in an organism that results in the killing of its own cells or those of another organism, including in some cases the death of the other organism. Killing here refers to the induction of death in one cell by another cell, not cell-autonomous death due to internal or other environmental conditions.


acetyl group

A group, formally derived from acetic acid by dehydroxylation, which is fundamental to the biochemistry of all forms of life. When bound to coenzyme A, it is central to the metabolism of carbohydrates and fats.


An aromatic ether that is aniline in which the hydrogen at position 4 is replaced by an ethoxy group. It is a hydrolysis metabolite of phenacetin.


name: positive regulation of cellular component biogenesis

description: Any process that activates or increases the frequency, rate or extent of cellular component biogenesis, a process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component.


magnesium ion transport

description: The directed movement of magnesium (Mg) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


name: positive regulation of T cell costimulation

description: Any process that activates or increases the frequency, rate or extent of T cell costimulation.


name: negative regulation of proteolysis involved in protein catabolic process

description: Any process that stops, prevents or reduces the frequency, rate or extent of proteolysis involved in protein catabolic process.


name: regulation of nucleocytoplasmic transport

description: Any process that modulates the frequency, rate or extent of the directed movement of substances between the nucleus and the cytoplasm.


name: negative regulation of ubiquitin-dependent protein catabolic process

description: Any process that stops, prevents, or reduces the frequency, rate or extent of ubiquitin-dependent protein catabolic process.


hydroperoxide

A monosubstitution product of hydrogen peroxide, HOOH.


transmembrane-ephrin receptor activity

description: Combining with a transmembrane ephrin to initiate a change in cell activity.


axon guidance receptor activity

description: Combining with an extracellular messenger and transmitting the signal from one side of the membrane to the other to results in a change in cellular activity involved in axon guidance.


hippocampal commissure

description: The triangular subcallosal plate of commissural fibers resulting from the converging of the right and left fornix bundles which exchange numerous fibers and which curve back in the contralateral fornix to end in the hippocampus of the opposite side.


name: regulation of systemic arterial blood pressure

description: The process that modulates the force with which blood travels through the systemic arterial circulatory system. The process is controlled by a balance of processes that increase pressure and decrease pressure.


FK506 binding

description: Binding to a 23-membered macrolide lactone FK506.


peptidyl-proline modification

description: The modification of peptidyl-proline.


negative regulation of synapse assembly

description: Any process that stops, prevents, or reduces the frequency, rate or extent of synapse assembly, the aggregation, arrangement and bonding together of a set of components to form a synapse.


POZ domain binding

description: Binding to a POZ (poxvirus and zinc finger) domain of a protein, a protein-protein interaction domain found in many transcription factors.


p-NITROPHENYLPHOSPHATE

An aryl phosphate resulting from the mono-esterification of phosphoric acid with 4-nitrophenol.


name: CASP8 and FADD-like apoptosis regulator isoform h2 (human)

description: A CASP8 and FADD-like apoptosis regulator (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O15519-2.


presenilin-2 isoform PS2short (mouse)

A presenilin-2 isoform PS2short that is encoded in the genome of mouse. UniProtKB:Q61144-1, 298-448.


name: death-associated protein kinase 1 isoform 1 (mouse)

description: A death-associated protein kinase 1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q80YE7-1.


phospholipase A2 activator activity

description: Binds to and increases the activity of the enzyme phospholipase A2.


transcription corepressor binding

description: Binding to a transcription corepressor, a protein involved in negative regulation of transcription via protein-protein interactions with transcription factors and other proteins that negatively regulate transcription. Transcription corepressors do not bind DNA directly, but rather mediate protein-protein interactions between repressing transcription factors and the basal transcription machinery.


cellular response to X-ray

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of X-ray radiation. An X-ray is a form of electromagnetic radiation with a wavelength in the range of 10 nanometers to 100 picometers (corresponding to frequencies in the range 30 PHz to 3 EHz).


name: protein localization to pericentric heterochromatin

description: A process in which a protein is transported to, or maintained in the pericentric heterochromatin.


name: C5AR2_HUMAN C5a anaphylatoxin chemotactic receptor 2 (sprot)

description: A C5a anaphylatoxin chemotactic receptor 2 that is encoded in the genome of human.


CFAI_HUMAN Complement factor I (sprot)

A complement factor I that is encoded in the genome of human.


name: CR2_HUMAN Complement receptor type 2 (sprot)

description: A complement receptor type 2 that is encoded in the genome of human.


name: FHR3_HUMAN Complement factor H-related protein 3 (sprot)

description: A complement factor H-related protein 3 that is encoded in the genome of human.


G-quadruplex RNA binding

description: Binding to a G-quadruplex RNA structure, in which groups of four guanines adopt a flat, cyclic hydrogen-bonding arrangement known as a guanine tetrad.


name: cellular response to high light intensity

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a high light intensity stimulus.


retinal rod cell apoptotic process

description: Any apoptotic process in a retinal rod cell, one of the two photoreceptor cell types of the vertebrate retina.


Ral protein signal transduction

description: An intracellular signaling cassette in which a small monomeric GTPase of the RaI subfamily relays a signal.


name: negative regulation of tolerance induction

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of tolerance induction.


description: Catalysis of the reaction: N(4)-(beta-N-acetyl-D-glucosaminyl)-L-asparagine + H2O = N-acetyl-beta-D-glucosaminylamine + L-aspartate + H+.


trochlear nerve development

description: The process whose specific outcome is the progression of the trochlear nerve over time, from its formation to the mature structure. The trochlear nerve is a motor nerve and is the only cranial nerve to exit the brain dorsally. The trochlear nerve innervates the superior oblique muscle.


oculomotor nerve development

description: The process whose specific outcome is the progression of the oculomotor nerve over time, from its formation to the mature structure. This motor nerve innervates all extraocular muscles except the superior oblique and the lateral rectus muscles. The superior division supplies the levator palpebrae superioris and superior rectus muscles. The inferior division supplies the medial rectus, inferior rectus and inferior oblique muscles. This nerve also innervates the striated muscles of the eyelid. Pupillary constriction and lens movement are mediated by this nerve for near vision. In the orbit the inferior division sends branches that enter the ciliary ganglion where they form functional contacts (synapses) with the ganglion cells. The ganglion cells send nerve fibers into the back of the eye where they travel to ultimately innervate the ciliary muscle and the constrictor pupillae muscle.


oculomotor nerve

description: Cranial nerve which connects the midbrain to the extra-ocular and intra-ocular muscles.


histone methyltransferase complex

description: A multimeric complex that is able to catalyze the addition of methyl groups to histone proteins.


general adaptation syndrome

description: General adaptation syndrome is the set of changes in various organ systems of the body, especially the pituitary-endocrine system, in response to a wide range of strong external stimuli, both physiological and psychological. It is described as having three stages: alarm reaction, where the body detects the external stimulus; adaptation, where the body engages defensive countermeasures against the stressor; and exhaustion, where the body begins to run out of defenses.


response to insecticide

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insecticide stimulus. Insecticides are chemicals used to kill insects.


sperm plasma membrane

description: A plasma membrane that is part of a sperm cell.


glycolipid biosynthetic process

description: The chemical reactions and pathways resulting in the formation of glycolipid, a class of 1,2-di-O-acylglycerols joined at oxygen 3 by a glycosidic linkage to a carbohydrate part (usually a mono-, di- or tri-saccharide).


name: negative regulation of cell fate determination

description: Any process that stops, prevents or reduces the frequency, rate or extent of cell fate determination.


name: negative regulation of stomach neuroendocrine cell differentiation

description: Any process that decreases the rate, frequency or extent of the differentiation of a neuroendocrine cell in the stomach.


regulation of stem cell differentiation

description: Any process that modulates the frequency, rate or extent of stem cell differentiation.


name: biological process involved in interaction with symbiont

description: An interaction between two organisms living together in more or less intimate association. The term symbiont is used for the smaller (macro) of the two members of a symbiosis; the various forms of symbiosis include parasitism, commensalism and mutualism.


response to hydroperoxide

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydroperoxide stimulus. Hydroperoxides are monosubstitution products of hydrogen peroxide, HOOH.


mesonephric duct morphogenesis

description: The process in which the anatomical structures of the mesonephric duct are generated and organized. A mesonephric duct is a tube drains the mesonephros.


body morphogenesis

description: The process in which the anatomical structures of the soma are generated and organized.


name: EIF3B_MOUSE Eukaryotic translation initiation factor 3 subunit B (sprot)

description: A eukaryotic translation initiation factor 3 subunit B that is encoded in the genome of mouse.


name: IF4A2_MOUSE Eukaryotic initiation factor 4A-II (sprot)

description: A eukaryotic initiation factor 4A-II that is encoded in the genome of mouse.


name: translation repressor activity, non-nucleic acid binding

description: Antagonizes the ribosome-mediated translation of mRNA into a polypeptide but does not bind directly to nucleic acid.


PMEPA_HUMAN Protein TMEPAI (sprot)

A protein TMEPAI that is encoded in the genome of human.


name: BAMBI_HUMAN BMP and activin membrane-bound inhibitor homolog (sprot)

description: A BMP and activin membrane-bound inhibitor that is encoded in the genome of human.


CATB_MOUSE Cathepsin B (sprot)

A cathepsin B that is encoded in the genome of mouse.


name: DPP2_MOUSE Dipeptidyl peptidase 2 (sprot)

description: A dipeptidyl peptidase 2 that is encoded in the genome of mouse.


name: HEXA_MOUSE Beta-hexosaminidase subunit alpha (sprot)

description: A beta-hexosaminidase subunit alpha that is encoded in the genome of mouse.


name: glutamate-cysteine ligase catalytic subunit binding

description: Binding to the catalytic subunit of glutamate-cysteine ligase.


name: positive regulation of glutamate-cysteine ligase activity

description: Any process that activates or increases the activity of glutamate-cysteine ligase, typically by lowering its sensitivity to inhibition by glutathione and by increasing its affinity for glutamate.


name: TBP_HUMAN TATA-box-binding protein (sprot)

description: A TATA-box-binding protein that is encoded in the genome of human.


name: UBF1_HUMAN Nucleolar transcription factor 1 (sprot)

description: A nucleolar transcription factor 1 that is encoded in the genome of human.


name: RRN3_HUMAN RNA polymerase I-specific transcription initiation factor RRN3 (sprot)

description: An RNA polymerase I-specific transcription initiation factor RRN3 that is encoded in the genome of human.


name: RPAC1_HUMAN DNA-directed RNA polymerases I and III subunit RPAC1 (sprot)

description: A DNA-directed RNA polymerases I and III subunit RPAC1 that is encoded in the genome of human.


name: RPA12_HUMAN DNA-directed RNA polymerase I subunit RPA12 (sprot)

description: A DNA-directed RNA polymerase I subunit RPA12 that is encoded in the genome of human.


name: RPAB5_HUMAN DNA-directed RNA polymerases I, II, and III subunit RPABC5 (sprot)

description: A DNA-directed RNA polymerases I, II, and III subunit RPABC5 that is encoded in the genome of human.


name: RPAB3_HUMAN DNA-directed RNA polymerases I, II, and III subunit RPABC3 (sprot)

description: A DNA-directed RNA polymerases I, II, and III subunit RPABC3 that is encoded in the genome of human.


name: RPC22_HUMAN Protein POLR1D, isoform 2 (sprot)


name: RPA1_HUMAN DNA-directed RNA polymerase I subunit RPA1 (sprot)

description: A DNA-directed RNA polymerase I subunit RPA1 that is encoded in the genome of human.


name: RPAB4_HUMAN DNA-directed RNA polymerases I, II, and III subunit RPABC4 (sprot)

description: A DNA-directed RNA polymerases I, II, and III subunit RPABC4 that is encoded in the genome of human.


name: RPAB2_HUMAN DNA-directed RNA polymerases I, II, and III subunit RPABC2 (sprot)

description: A DNA-directed RNA polymerases I, II, and III subunit RPABC2 that is encoded in the genome of human.


name: RPAB1_HUMAN DNA-directed RNA polymerases I, II, and III subunit RPABC1 (sprot)

description: A DNA-directed RNA polymerases I, II, and III subunit RPABC1 that is encoded in the genome of human.


name: TAF1D_HUMAN TATA box-binding protein-associated factor RNA polymerase I subunit D (sprot)

description: A TATA box-binding protein-associated factor RNA polymerase I subunit D that is encoded in the genome of human.


name: TAF1B_HUMAN TATA box-binding protein-associated factor RNA polymerase I subunit B (sprot)

description: A TATA box-binding protein-associated factor RNA polymerase I subunit B that is encoded in the genome of human.


name: TAF1A_HUMAN TATA box-binding protein-associated factor RNA polymerase I subunit A (sprot)

description: A TATA box-binding protein-associated factor RNA polymerase I subunit A that is encoded in the genome of human.


name: RPA34_HUMAN DNA-directed RNA polymerase I subunit RPA34 (sprot)

description: A DNA-directed RNA polymerase I subunit RPA34 that is encoded in the genome of human.


name: TAF1C_HUMAN TATA box-binding protein-associated factor RNA polymerase I subunit C (sprot)

description: A TATA box-binding protein-associated factor RNA polymerase I subunit C that is encoded in the genome of human.


name: RPA49_HUMAN DNA-directed RNA polymerase I subunit RPA49 (sprot)

description: A DNA-directed RNA polymerase I subunit RPA49 that is encoded in the genome of human.


name: RPA2_HUMAN DNA-directed RNA polymerase I subunit RPA2 (sprot)

description: A DNA-directed RNA polymerase I subunit RPA2 that is encoded in the genome of human.


name: RPA43_HUMAN DNA-directed RNA polymerase I subunit RPA43 (sprot)

description: A DNA-directed RNA polymerase I subunit RPA43 that is encoded in the genome of human.


aryl hydrocarbon receptor binding

description: Binding to an aryl hydrocarbon receptor.


PHENYLACETALDEHYDE

An aldehyde that consists of acetaldehyde bearing a methyl substituent; the parent member of the phenylacetaldehyde class of compounds.


A propanal having an amino substituent at the 3-position


N-benzoylglycinate

An alpha-amino-acid anion that is the conjugate base of N-benzoylglycine; major species at pH 7.3.


An N-acyl-L-alpha-amino acid anion that is the conjugate base of N(2)-phenylacetyl-L-glutamine; major species at pH 7.3.


resveratrol

A stilbenol that is stilbene in which the phenyl groups are substituted at positions 3, 5, and 4' by hydroxy groups.


PERFOSFAMIDE

A phosphorodiamide that is the active metabolite of the nitrogen mustard cyclophosphamide. It has potent antineoplastic and immunosuppressive properties.


doxorubicinol

A member of the class of tetracenequinones that is the major metabolite of the anthracycline doxorubicin, a chemotherapeutic agent effective against a broad range of malignant neoplasms. It is thought to exhibit cardiotoxic properties.


BENZALDEHYDE

An arenecarbaldehyde that consists of benzene bearing a single formyl substituent; the simplest aromatic aldehyde and parent of the class of benzaldehydes.


THERACYS

A  benzoate ester metabolite of cocaine formed by hydrolysis of the methyl ester group, catalysed by carboxylesterases.


An isoquinoline that is 3,4-dihydroisoquinoline bearing amidino and hydroxy substituent at positions 2 and 4 respectively.


cyclopropylamine

A primary aliphatic amine that consists of cyclopropane bearing a single amino substituent.


tamoxifen N-oxide

A tertiary amine oxide resulting from the formal oxidation of the amino group of tamoxifen.


aminosalicylic acid

An aminobenzoic acid that is salicylic acid substituted by an amino group at position 4.


N'-acetylisoniazid

A carbohydrazide resulting from the formal condensation of the carboxy group of isonicotinic acid with hydrazine and subsequent acetylation of the monosubstituted nitrogen atom.


name: AHRR_HUMAN Aryl hydrocarbon receptor repressor (sprot)

description: An aryl hydrocarbon receptor repressor that is encoded in the genome of human.


name: ARNT2_HUMAN Aryl hydrocarbon receptor nuclear translocator 2 (sprot)

description: An aryl hydrocarbon receptor nuclear translocator 2 that is encoded in the genome of human.


sulfanilamide

A sulfonamide in which the sulfamoyl functional group is attached to aniline at the 4-position.


An N-acetoxyarylamine having 1,1'-biphenyl-4-amine as the arylamine component.


An amidobenzoate that is the conjugate base of 4-acetamidobenzoic acid, arising from deprotonation of the carboxy group; major species at pH 7.3.


An amidobenzoate that is the conjugate base of 4-acetamidosalicylic acid, arising from deprotonation of the carboxy group; major species at pH 7.3.


sulfacetamide

A sulfonamide that is sulfanilamide acylated on the sulfonamide nitrogen.


name: large conductance calcium-activated potassium channel activity

description: Enables the transmembrane transfer of potassium by a channel with a unit conductance of 100 to 220 picoSiemens that opens in response to stimulus by concerted actions of internal calcium ions and membrane potential. Large conductance calcium-activated potassium channels are less sensitive to calcium than are small or intermediate conductance calcium-activated potassium channels. Transport by a channel involves catalysis of facilitated diffusion of a solute (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel, without evidence for a carrier-mediated mechanism.


negative regulation of cell volume

description: Any process that decreases cell volume.


negative regulation of p38MAPK cascade

description: Any process that stops, prevents or reduces the frequency, rate or extent of p38MAPK cascade.


name: negative regulation of establishment of protein localization to mitochondrion

description: Any process that stops, prevents or reduces the frequency, rate or extent of establishment of protein localization to mitochondrion.


name: negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide

description: Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to hydrogen peroxide.


name: R4JNM3_MOUSE Anti-Mullerian hormone type 2 receptor delta 9/10 (Fragment) (trembl)

description: An anti-Muellerian hormone type-2 receptor isoform Delta9/10 that is encoded in the genome of mouse. This sequence lacks the region encoded by exons 9 and 10, which is part of the protein kinase domain.


name: negative regulation of anti-Mullerian hormone signaling pathway

description: Any process that stops, prevents or reduces the frequency, rate or extent of anti-Mullerian hormone signaling pathway.


name: R4JKA2_MOUSE Anti-Mullerian hormone type 2 receptor delta 2 (Fragment) (trembl)

description: An anti-Muellerian hormone type-2 receptor isoform Delta2 that is encoded in the genome of mouse. This sequence lacks the region encoded by exon 2 which is part of the extracellular domain and it is essential for ligand binding.


name: anti-Muellerian hormone type-2 receptor isoform 1 (mouse)

description: An anti-Muellerian hormone type-2 receptor isoform 1 that is encoded in the genome of mouse.


name: anti-Mullerian hormone receptor activity

description: Combining with anti-Mullerian hormone to initiate a change in cell activity.


name: anti-Mullerian hormone receptor signaling pathway

description: The series of molecular signals initiated by the binding of anti-Mullerian hormone to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. Upon ligand binding, the receptor  forms a complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators.


name: brush border cell of the proximal tubule

description: A brush border epithelial cell located in the proximal tubule of the kidney that detects fluid flow.


antral ovarian follicle growth

description: Increase in size of antral follicles due to cell proliferation and/or growth of the antral cavity.


name: follicle-stimulating hormone signaling pathway

description: A G protein-coupled receptor signaling pathway initiated by follicle-stimulating hormone binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process.


name: activation of prostate induction by androgen receptor signaling pathway

description: The series of molecular signals initiated by androgen binding to its receptor in the urogenital sinus mesenchyme that initiates prostate induction. Prostate induction is the close range interaction of the urogenital sinus mesenchyme and the urogenital sinus epithelium that causes the cells of the urogenital sinus epithelium to change their fates and specify the development of the prostate gland.


name: tyrosine-protein kinase SYK isoform 1 phosphorylated 6 (mouse)

description: A tyrosine-protein kinase SYK isoform 1 (mouse) that lacks a phosphorylated Tyr at positions 519 and 520, but it is still phosphorylated at Tyr 342 and 346. UniProtKB:P48025-1, Tyr-342/Tyr-346, MOD:00048|Tyr-519/Tyr-520, PR:000026291.


name: tyrosine-protein kinase SYK isoform 1 unphosphorylated 3 (mouse)

description: A tyrosine-protein kinase SYK isoform 1 (mouse) that lacks a phosphorylated Tyr at position 346. UniProtKB:P48025-1, Tyr-346, PR:000026291.


name: tyrosine-protein kinase SYK isoform 1 unphosphorylated 2 (mouse)

description: A tyrosine-protein kinase SYK isoform 1 (mouse) that lacks a phosphorylated Tyr at position 342. UniProtKB:P48025-1, Tyr-342, PR:000026291.


name: tyrosine-protein kinase SYK isoform 1 phosphorylated 2 (mouse)

description: A tyrosine-protein kinase SYK isoform 1 (mouse) that has been phosphorylated on Tyr-342. UniProtKB:P48025-1, Tyr-342, MOD:00048.


name: tyrosine-protein kinase SYK isoform 1 phosphorylated 5 (mouse)

description: A tyrosine-protein kinase SYK isoform 1 (mouse) that has been phosphorylated on Tyr-342, Tyr-346, Tyr-519 and Tyr-520. UniProtKB:P48025-1, Tyr-342/Tyr-346/Tyr-519/Tyr-520, MOD:00048.


name: tyrosine-protein kinase SYK isoform 1 phosphorylated 4 (mouse)

description: A tyrosine-protein kinase SYK isoform 1 (mouse) that has been phosphorylated on Tyr-342 and Tyr-346. UniProtKB:P48025-1, Tyr-342/Tyr-346, MOD:00048.


name: positive regulation of response to type II interferon

description: Any process that increases the rate, frequency or extent of a response to type II interferon (interferon-gamma). Response to interferon gamma is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-gamma stimulus.


interleukin-8 receptor activity

description: Combining with interleukin-8 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


microtubule anchoring at centrosome

description: Any process in which a microtubule is maintained in a specific location in a cell by attachment to a centrosome.


description: The 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates from the centrosome.


regulation of microtubule-based process

description: Any process that modulates the frequency, rate or extent of any cellular process that depends upon or alters the microtubule cytoskeleton.


name: negative regulation of T-helper 2 cell differentiation

description: Any process that stops, prevents, or reduces the frequency, rate or extent of T-helper 2 cell differentiation.


small ribosomal subunit

description: The smaller of the two subunits of a ribosome.


name: negative regulation of membrane protein ectodomain proteolysis

description: Any process that stops, prevents, or reduces the frequency, rate or extent of membrane protein ectodomain proteolysis.


name: positive regulation of membrane protein ectodomain proteolysis

description: Any process that activates or increases the frequency, rate or extent of membrane protein ectodomain peptidolysis.


name: neuregulin-1 type I-beta1a transmembrane precursor (mouse)

description: A neuregulin-1 type I-beta1a (mouse) that has not been proteolytically processed.


name: neuregulin-1 type I-beta4a transmembrane precursor (mouse)

description: A neuregulin-1 type I-beta4a (mouse) that has not been proteolytically processed.


name: negative regulation of cell cycle G1/S phase transition

description: Any signaling pathway that decreases or inhibits the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G1 phase to S phase of the cell cycle.


climbing fiber

description: The axon of inferior olive neuron that projects to the cerebellar cortex, largely via the inferior cerebellar peduncle. They range in diameter from 1-3 um and are myelinated until they enter the granule cell layer. They give off collaterals to the deep cerebellar nuclei. They synapse extensively with the dendrites of Purkinje cells in the molecular layer, where each fiber branches repeatedly to climb along the Purkinje cell dendritic tree. Each Purkinje cell is innervated by only a single climbing fiber.


cerebellar molecular layer development

description: The process whose specific outcome is the progression of the cerebellar molecular layer nerve over time, from its formation to the mature structure. The molecular layer is the outermost layer of the cerebellar cortex. It contains the parallel fibers of the granule cells, interneurons such as stellate and basket cells, and the dendrites of the underlying Purkinje cells.


L-cysteine catabolic process to taurine

description: The chemical reactions and pathways resulting in the breakdown of L-cysteine into other compounds, including taurine.


hedgehog receptor activity

description: Combining with a member of the hedgehog protein family and transmitting the signal across the membrane to initiate a change in cell activity.


name: positive regulation of epidermal cell differentiation

description: Any process that activates or increases the frequency, rate or extent of epidermal cell differentiation.


response to chlorate

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chlorate stimulus.


name: planar cell polarity pathway involved in pericardium morphogenesis

description: The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity that contributes to the shaping of the pericardium.


prevention of polyspermy

description: The negative regulation of fertilization process that takes place as part of egg activation, ensuring that only a single sperm fertilizes the egg.


name: regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity

description: Any process that modulates the frequency, rate or extent of the activity of the inositol 1,4,5-trisphosphate-sensitive calcium-release channel.


name: oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor

description: Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and reduces an oxygen molecule.


name: mitochondrial electron transfer flavoprotein complex

description: A protein complex located in the mitochondrion. It contains flavin adenine dinucleotide (FAD) that, together with an acyl-CoA dehydrogenase, forms a system that oxidizes an acyl-CoA molecule and reduces ubiquinone and other acceptors in the mitochondrial electron transport system.


name: mesenchymal stem cell maintenance involved in metanephric nephron morphogenesis

description: The process in which an organism retains a population of mesenchymal stem cells that contributes to the shaping of a nephron in the metanephros. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells.