name: GHRHR_MOUSE Growth hormone-releasing hormone receptor (sprot)

description: A growth hormone-releasing hormone receptor that is encoded in the genome of mouse.


SLIB_MOUSE Somatoliberin (sprot)

A somatoliberin that is encoded in the genome of mouse.


name: CXB6_MOUSE Gap junction beta-6 protein (sprot)

description: A gap junction beta-6 protein that is encoded in the genome of mouse.


DREB_MOUSE Drebrin (sprot)

A drebrin that is encoded in the genome of mouse.


name: SUFU_MOUSE Suppressor of fused homolog (sprot)

description: A suppressor of fused homolog that is encoded in the genome of mouse.


name: SIR4_MOUSE NAD-dependent protein lipoamidase sirtuin-4, mitochondrial (sprot)

description: An NAD-dependent protein lipoamidase sirtuin-4, mitochondrial that is encoded in the genome of mouse.


SNG2_MOUSE Synaptogyrin-2 (sprot)

A synaptogyrin-2 that is encoded in the genome of mouse.


name: PE2R3_MOUSE Prostaglandin E2 receptor EP3 subtype (sprot)

description: A prostaglandin E2 receptor EP3 subtype that is encoded in the genome of mouse.


name: AA1R_MOUSE Adenosine receptor A1 (sprot)

description: An adenosine receptor A1 that is encoded in the genome of mouse.


name: LIME1_MOUSE Lck-interacting transmembrane adapter 1 (sprot)

description: An lck-interacting transmembrane adapter 1 that is encoded in the genome of mouse.


name: GAB3_MOUSE GRB2-associated-binding protein 3 (sprot)

description: A GRB2-associated-binding protein 3 that is encoded in the genome of mouse.


name: FRS2_MOUSE Fibroblast growth factor receptor substrate 2 (sprot)

description: A fibroblast growth factor receptor substrate 2 that is encoded in the genome of mouse.


name: SHAN3_MOUSE SH3 and multiple ankyrin repeat domains protein 3 (sprot)

description: An SH3 and multiple ankyrin repeat domains protein 3 that is encoded in the genome of mouse.


ALS2_MOUSE Alsin (sprot)

An alsin that is encoded in the genome of mouse.


NOE2_MOUSE Noelin-2 (sprot)

A noelin-2 that is encoded in the genome of mouse.


name: GRIA3_MOUSE Glutamate receptor 3 (sprot)

description: A glutamate receptor 3 that is encoded in the genome of mouse.


name: glutamate receptor ionotropic, kainate 2 isoform 1 (mouse)

description: A glutamate receptor ionotropic, kainate 2 isoform 1 that is encoded in the genome of mouse.


name: glutamate receptor ionotropic, kainate 2 isoform 2 (mouse)

description: A glutamate receptor ionotropic, kainate 2 isoform 2 that is encoded in the genome of mouse.


name: NETO1_MOUSE Neuropilin and tolloid-like protein 1 (sprot)

description: A neuropilin and tolloid-like protein 1 that is encoded in the genome of mouse.


name: DPYL3_MOUSE Dihydropyrimidinase-related protein 3 (sprot)

description: A dihydropyrimidinase-related protein 3 that is encoded in the genome of mouse.


name: DPYL2_MOUSE Dihydropyrimidinase-related protein 2 (sprot)

description: A dihydropyrimidinase-related protein 2 that is encoded in the genome of mouse.


GRD2I_MOUSE Delphilin (sprot)

A delphilin that is encoded in the genome of mouse.


name: NETO2_MOUSE Neuropilin and tolloid-like protein 2 (sprot)

description: A neuropilin and tolloid-like protein 2 that is encoded in the genome of mouse.


SNX27_MOUSE Sorting nexin-27 (sprot)

A sorting nexin-27 that is encoded in the genome of mouse.


name: SHC3_MOUSE SHC-transforming protein 3 (sprot)

description: An SHC-transforming protein 3 that is encoded in the genome of mouse.


name: PTN4_MOUSE Tyrosine-protein phosphatase non-receptor type 4 (sprot)

description: A tyrosine-protein phosphatase non-receptor type 4 that is encoded in the genome of mouse.


name: AGRF1_MOUSE Adhesion G-protein coupled receptor F1 (sprot)

description: An adhesion G-protein coupled receptor F1 that is encoded in the genome of mouse.


name: DNJC1_MOUSE DnaJ homolog subfamily C member 1 (sprot)

description: A DnaJ homolog subfamily C member 1 that is encoded in the genome of mouse.


SPA12_MOUSE Serpin A12 (sprot)

A serpin A12 that is encoded in the genome of mouse.


name: FKBP7_MOUSE Peptidyl-prolyl cis-trans isomerase FKBP7 (sprot)

description: A peptidyl-prolyl cis-trans isomerase FKBP7 that is encoded in the genome of mouse.


name: HDA11_MOUSE Histone deacetylase 11 (sprot)

description: A histone deacetylase 11 that is encoded in the genome of mouse.


FBX2_MOUSE F-box only protein 2 (sprot)

An F-box only protein 2 that is encoded in the genome of mouse.


name: GSTM2_MOUSE Glutathione S-transferase Mu 2 (sprot)

description: A glutathione S-transferase mu that is a translation product of the Gstm2 gene in mouse.


name: TAP1_MOUSE Antigen peptide transporter 1 (sprot)

description: An antigen peptide transporter 1 that is encoded in the genome of mouse.


name: TAP2_MOUSE Antigen peptide transporter 2 (sprot)

description: An antigen peptide transporter 2 that is encoded in the genome of mouse.


name: DMA_MOUSE Class II histocompatibility antigen, M alpha chain (sprot)

description: A class II histocompatibility antigen, M alpha chain that is encoded in the genome of mouse.


name: ZN592_MOUSE Zinc finger protein 592 (sprot)

description: A zinc finger protein 592 that is encoded in the genome of mouse.


name: LONP2_MOUSE Lon protease homolog 2, peroxisomal (sprot)

description: A peroxisomal Lon protease 2 that is encoded in the genome of mouse.


name: SAFB1_MOUSE Scaffold attachment factor B1 (sprot)

description: A scaffold attachment factor B1 that is encoded in the genome of mouse.


name: SRFB1_MOUSE Serum response factor-binding protein 1 (sprot)

description: A serum response factor-binding protein 1 that is encoded in the genome of mouse.


name: ZMIZ1_MOUSE Zinc finger MIZ domain-containing protein 1 (sprot)

description: A zinc finger MIZ domain-containing protein 1 that is encoded in the genome of mouse.


name: FCRL5_MOUSE Fc receptor-like protein 5 (sprot)

description: A protein that is a translation product of the Fcrl5 gene in mouse.


name: CD5_MOUSE T-cell surface glycoprotein CD5 (sprot)

description: A T-cell surface glycoprotein CD5 that is encoded in the genome of mouse.


hexokinase-1 isoform 1 (mouse)

A hexokinase-1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P17710-1.


name: PFKAM_MOUSE ATP-dependent 6-phosphofructokinase, muscle type (sprot)

description: An ATP-dependent 6-phosphofructokinase, muscle type that is encoded in the genome of mouse.


KPYM_MOUSE Pyruvate kinase PKM (sprot)

A pyruvate kinase PKM that is encoded in the genome of mouse.


name: CA2D1_MOUSE Voltage-dependent calcium channel subunit alpha-2/delta-1 (sprot)

description: A voltage-dependent calcium channel subunit alpha-2/delta-1 that is encoded in the genome of mouse.


name: G3P_MOUSE Glyceraldehyde-3-phosphate dehydrogenase (sprot)

description: A glyceraldehyde-3-phosphate dehydrogenase that is encoded in the genome of mouse.


name: PRS7_MOUSE 26S proteasome regulatory subunit 7 (sprot)

description: A 26S proteasome regulatory subunit 7 that is encoded in the genome of mouse.


name: HYPK_MOUSE Huntingtin-interacting protein K (sprot)

description: A huntingtin-interacting protein K that is encoded in the genome of mouse.


name: USP9X_MOUSE Ubiquitin carboxyl-terminal hydrolase 9X (sprot)

description: A probable ubiquitin carboxyl-terminal hydrolase FAF-X that is encoded in the genome of mouse.


name: PARP1_MOUSE Poly [ADP-ribose] polymerase 1 (sprot)

description: A poly [ADP-ribose] polymerase 1 that is encoded in the genome of mouse.


name: STK33_MOUSE Serine/threonine-protein kinase 33 (sprot)

description: A protein that is a translation product of the Stk33 gene in mouse.


name: TTC36_MOUSE Tetratricopeptide repeat protein 36 (sprot)

description: A tetratricopeptide repeat protein 36 that is encoded in the genome of mouse.


name: LMF1_MOUSE Lipase maturation factor 1 (sprot)

description: A lipase maturation factor 1 that is encoded in the genome of mouse.


name: RASF1_MOUSE Ras association domain-containing protein 1 (sprot)

description: A Ras association domain-containing protein 1 that is encoded in the genome of mouse.


name: MCR_MOUSE Mineralocorticoid receptor (sprot)

description: A mineralocorticoid receptor that is encoded in the genome of mouse.


name: HECD1_MOUSE E3 ubiquitin-protein ligase HECTD1 (sprot)

description: An E3 ubiquitin-protein ligase HECTD1 that is encoded in the genome of mouse.


name: VWA1_MOUSE von Willebrand factor A domain-containing protein 1 (sprot)

description: A von Willebrand factor A domain-containing protein 1 that is encoded in the genome of mouse.


name: SH3L2_MOUSE SH3 domain-binding glutamic acid-rich-like protein 2 (sprot)

description: An SH3 domain-binding glutamic acid-rich-like protein 2 that is encoded in the genome of mouse.


SOST_MOUSE Sclerostin (sprot)

A sclerostin that is encoded in the genome of mouse.


name: MEF2D_MOUSE Myocyte-specific enhancer factor 2D (sprot)

description: A myocyte-specific enhancer factor 2D that is encoded in the genome of mouse.


POLK_MOUSE DNA polymerase kappa (sprot)

A DNA polymerase kappa that is encoded in the genome of mouse.


name: TAF8_MOUSE Transcription initiation factor TFIID subunit 8 (sprot)

description: A transcription initiation factor TFIID subunit 8 that is encoded in the genome of mouse.


name: NR1D2_MOUSE Nuclear receptor subfamily 1 group D member 2 (sprot)

description: A nuclear receptor subfamily 1 group D member 2 that is encoded in the genome of mouse.


BCOR_MOUSE BCL-6 corepressor (sprot)

A BCL-6 corepressor that is encoded in the genome of mouse.


name: SENP1_MOUSE Sentrin-specific protease 1 (sprot)

description: A sentrin-specific protease 1 that is encoded in the genome of mouse.


PRTN3_MOUSE Myeloblastin (sprot)

A myeloblastin that is encoded in the genome of mouse.


name: IGF1_MOUSE Insulin-like growth factor I (sprot)

description: An insulin-like growth factor I that is encoded in the genome of mouse.


SNX9_MOUSE Sorting nexin-9 (sprot)

A sorting nexin-9 that is encoded in the genome of mouse.


PR2C2_MOUSE Prolactin-2C2 (sprot)

A prolactin-2C2 that is encoded in the genome of mouse.


name: IBP5_MOUSE Insulin-like growth factor-binding protein 5 (sprot)

description: An insulin-like growth factor-binding protein 5 that is encoded in the genome of mouse.


name: MYORG_MOUSE Myogenesis-regulating glycosidase (sprot)

description: A myogenesis-regulating glycosidase that is encoded in the genome of mouse.


name: MPRI_MOUSE Cation-independent mannose-6-phosphate receptor (sprot)

description: A cation-independent mannose-6-phosphate receptor that is encoded in the genome of mouse.


name: IBP1_MOUSE Insulin-like growth factor-binding protein 1 (sprot)

description: An insulin-like growth factor-binding protein 1 that is encoded in the genome of mouse.


name: IBP4_MOUSE Insulin-like growth factor-binding protein 4 (sprot)

description: An insulin-like growth factor-binding protein 4 that is encoded in the genome of mouse.


name: IBP2_MOUSE Insulin-like growth factor-binding protein 2 (sprot)

description: An insulin-like growth factor-binding protein 2 that is encoded in the genome of mouse.


name: IBP3_MOUSE Insulin-like growth factor-binding protein 3 (sprot)

description: An insulin-like growth factor-binding protein 3 that is encoded in the genome of mouse.


name: CD79A_MOUSE B-cell antigen receptor complex-associated protein alpha chain (sprot)

description: A B-cell antigen receptor complex-associated protein alpha chain that is encoded in the genome of mouse.


name: VPREB_MOUSE Immunoglobulin iota chain (sprot)

description: A protein that is a translation product of the Vpreb1 gene in mouse.


CAD17_MOUSE Cadherin-17 (sprot)

A cadherin-17 that is encoded in the genome of mouse.


name: CD1D1_MOUSE Antigen-presenting glycoprotein CD1d1 (sprot)

description: An antigen-presenting glycoprotein CD1d that is encoded in the genome of mouse.


name: IRAK4_MOUSE Interleukin-1 receptor-associated kinase 4 (sprot)

description: An interleukin-1 receptor-associated kinase 4 that is encoded in the genome of mouse.


name: RBM15_MOUSE RNA-binding protein 15 (sprot)

description: An RNA-binding protein 15 that is encoded in the genome of mouse.


IL16_MOUSE Pro-interleukin-16 (sprot)

An interleukin-16 that is encoded in the genome of mouse.


NPNT_MOUSE Nephronectin (sprot)

A nephronectin that is encoded in the genome of mouse.


name: SOCS1_MOUSE Suppressor of cytokine signaling 1 (sprot)

description: A suppressor of cytokine signaling 1 that is encoded in the genome of mouse.


FINC_MOUSE Fibronectin (sprot)

A fibronectin that is encoded in the genome of mouse.


ITB4_MOUSE Integrin beta-4 (sprot)

An integrin beta-4 that is encoded in the genome of mouse.


ITA5_MOUSE Integrin alpha-5 (sprot)

An integrin alpha-5 that is encoded in the genome of mouse.


ITA6_MOUSE Integrin alpha-6 (sprot)

An integrin alpha-6 that is encoded in the genome of mouse.


name: PTX3_MOUSE Pentraxin-related protein PTX3 (sprot)

description: A pentraxin-related protein PTX3 that is encoded in the genome of mouse.


name: PDIA4_MOUSE Protein disulfide-isomerase A4 (sprot)

description: A protein disulfide-isomerase A4 that is encoded in the genome of mouse.


name: ABL2_MOUSE Tyrosine-protein kinase ABL2 (sprot)

description: A tyrosine-protein kinase ABL2 that is encoded in the genome of mouse.


name: NRK2_MOUSE Nicotinamide riboside kinase 2 (sprot)

description: A nicotinamide riboside kinase 2 that is encoded in the genome of mouse.


ITA3_MOUSE Integrin alpha-3 (sprot)

An integrin alpha-3 that is encoded in the genome of mouse.


name: CAH8_MOUSE Carbonic anhydrase-related protein (sprot)

description: A carbonic anhydrase-related protein that is encoded in the genome of mouse.


DSG1A_MOUSE Desmoglein-1-alpha (sprot)

A desmoglein-1-alpha that is encoded in the genome of mouse.


name: MAFB_MOUSE Transcription factor MafB (sprot)

description: A transcription factor MafB that is encoded in the genome of mouse.


name: TNR3_MOUSE Tumor necrosis factor receptor superfamily member 3 (sprot)

description: A tumor necrosis factor receptor superfamily member 3 that is encoded in the genome of mouse.


name: SPRE2_MOUSE Sprouty-related, EVH1 domain-containing protein 2 (sprot)

description: A sprouty-related, EVH1 domain-containing protein 2 that is encoded in the genome of mouse.


SCF_MOUSE Kit ligand (sprot)

A kit ligand that is encoded in the genome of mouse.


name: SPRE1_MOUSE Sprouty-related, EVH1 domain-containing protein 1 (sprot)

description: A sprouty-related, EVH1 domain-containing protein 1 that is encoded in the genome of mouse.


name: SH2B3_MOUSE SH2B adapter protein 3 (sprot)

description: An SH2B adapter protein 3 that is encoded in the genome of mouse.


name: STAP1_MOUSE Signal-transducing adaptor protein 1 (sprot)

description: A signal-transducing adaptor protein 1 that is encoded in the genome of mouse.


PLSI_MOUSE Plastin-1 (sprot)

A plastin-1 that is encoded in the genome of mouse.


name: VSTM4_MOUSE V-set and transmembrane domain-containing protein 4 (sprot)

description: A V-set and transmembrane domain-containing protein 4 that is encoded in the genome of mouse.


name: PDCL3_MOUSE Phosducin-like protein 3 (sprot)

description: A phosducin-like protein 3 that is encoded in the genome of mouse.


name: K1C13_MOUSE Keratin, type I cytoskeletal 13 (sprot)

description: A keratin, type I cytoskeletal 13 that is encoded in the genome of mouse.


name: K1C25_MOUSE Keratin, type I cytoskeletal 25 (sprot)

description: A keratin, type I cytoskeletal 25 that is encoded in the genome of mouse.


name: HS105_MOUSE Heat shock protein 105 kDa (sprot)

description: A heat shock protein 105 kDa that is encoded in the genome of mouse.


name: LAMA5_MOUSE Laminin subunit alpha-5 (sprot)

description: A laminin subunit alpha-5 that is encoded in the genome of mouse.


name: CYLD_MOUSE Ubiquitin carboxyl-terminal hydrolase CYLD (sprot)

description: A ubiquitin carboxyl-terminal hydrolase CYLD that is encoded in the genome of mouse.


name: SRCRL_MOUSE Soluble scavenger receptor cysteine-rich domain-containing protein SSC5D (sprot)

description: A soluble scavenger receptor cysteine-rich domain-containing protein SSC5D that is encoded in the genome of mouse.


CUBN_MOUSE Cubilin (sprot)

A cubilin that is encoded in the genome of mouse.


SNX17_MOUSE Sorting nexin-17 (sprot)

A sorting nexin-17 that is encoded in the genome of mouse.


name: ARH_MOUSE Low density lipoprotein receptor adapter protein 1 (sprot)

description: A low density lipoprotein receptor adapter protein 1 that is encoded in the genome of mouse.


name: IL6RB_MOUSE Interleukin-6 receptor subunit beta (sprot)

description: An interleukin-6 receptor subunit beta that is encoded in the genome of mouse.


CTF2_MOUSE Cardiotrophin-2 (sprot)

A cardiotrophin-2 that is encoded in the genome of mouse.


name: U5S1_MOUSE 116 kDa U5 small nuclear ribonucleoprotein component (sprot)

description: A 116 kDa U5 small nuclear ribonucleoprotein component that is encoded in the genome of mouse.


An alpha-2-macroglobulin that is encoded in the genome of mouse.


name: FBLN4_MOUSE EGF-containing fibulin-like extracellular matrix protein 2 (sprot)

description: An EGF-containing fibulin-like extracellular matrix protein 2 that is encoded in the genome of mouse.


name: CLC2H_MOUSE C-type lectin domain family 2 member H (sprot)

description: A C-type lectin domain family 2 member H that is encoded in the genome of mouse.


name: RN180_MOUSE E3 ubiquitin-protein ligase RNF180 (sprot)

description: An E3 ubiquitin-protein ligase RNF180 that is encoded in the genome of mouse.


name: SAA3_MOUSE Serum amyloid A-3 protein (sprot)

description: A murine-type serum amyloid A-3 protein that is encoded in the genome of mouse.


TRYB2_MOUSE Tryptase beta-2 (sprot)

A tryptase alpha/beta-1 that is encoded in the genome of mouse.


name: RASF5_MOUSE Ras association domain-containing protein 5 (sprot)

description: A Ras association domain-containing protein 5 that is encoded in the genome of mouse.


name: PK1IP_MOUSE p21-activated protein kinase-interacting protein 1 (sprot)

description: A p21-activated protein kinase-interacting protein 1 that is encoded in the genome of mouse.


MTBP_MOUSE Mdm2-binding protein (sprot)

An Mdm2-binding protein that is encoded in the genome of mouse.


name: AAA1_MOUSE Asc-type amino acid transporter 1 (sprot)

description: An asc-type amino acid transporter 1 that is encoded in the genome of mouse.


name: PRD13_MOUSE PR domain zinc finger protein 13 (sprot)

description: A PR domain zinc finger protein 13 that is encoded in the genome of mouse.


name: PAX9_MOUSE Paired box protein Pax-9 (sprot)

description: A paired box protein Pax-9 that is encoded in the genome of mouse.


name: TRAF7_MOUSE E3 ubiquitin-protein ligase TRAF7 (sprot)

description: An E3 ubiquitin-protein ligase TRAF7 that is encoded in the genome of mouse.


name: FBX22_MOUSE F-box only protein 22 (sprot)

description: An F-box only protein 22 that is encoded in the genome of mouse.


name: NCF4_MOUSE Neutrophil cytosol factor 4 (sprot)

description: A neutrophil cytosol factor 4 that is encoded in the genome of mouse.


name: MYPC3_MOUSE Myosin-binding protein C, cardiac-type (sprot)

description: A myosin-binding protein C, cardiac-type that is encoded in the genome of mouse.


name: vascular endothelial growth factor C isoform 4 (mouse)

description: A vascular endothelial growth factor C isoform 4 that is encoded in the genome of mouse.


name: SETD3_MOUSE Actin-histidine N-methyltransferase (sprot)

description: An actin-histidine N-methyltransferase that is encoded in the genome of mouse.


name: BHE41_MOUSE Class E basic helix-loop-helix protein 41 (sprot)

description: A class E basic helix-loop-helix protein 41 that is encoded in the genome of mouse.


name: PPGB_MOUSE Lysosomal protective protein (sprot)

description: A lysosomal protective protein that is encoded in the genome of mouse.


name: EAA1_MOUSE Excitatory amino acid transporter 1 (sprot)

description: An excitatory amino acid transporter 1 that is encoded in the genome of mouse.


CYS1_MOUSE Cystin-1 (sprot)

A cystin-1 that is encoded in the genome of mouse.


name: N4BP1_MOUSE NEDD4-binding protein 1 (sprot)

description: A NEDD4-binding protein 1 that is encoded in the genome of mouse.


BEAN1_MOUSE Protein BEAN1 (sprot)

A protein BEAN that is encoded in the genome of mouse.


name: N4BP3_MOUSE NEDD4-binding protein 3 (sprot)

description: A NEDD4-binding protein 3 that is encoded in the genome of mouse.


name: KI26B_MOUSE Kinesin-like protein KIF26B (sprot)

description: A kinesin-like protein KIF26B that is encoded in the genome of mouse.


name: ANR42_MOUSE Ankyrin repeat domain-containing protein 42 (sprot)

description: A protein that is a translation product of the Ankrd42 gene in mouse.


REL_MOUSE Proto-oncogene c-Rel (sprot)

A proto-oncogene c-Rel that is encoded in the genome of mouse.


name: LAMC2_MOUSE Laminin subunit gamma-2 (sprot)

description: A laminin subunit gamma-2 that is encoded in the genome of mouse.


name: TBX2_MOUSE T-box transcription factor TBX2 (sprot)

description: A T-box transcription factor TBX2 that is encoded in the genome of mouse.


name: TLE3_MOUSE Transducin-like enhancer protein 3 (sprot)

description: A transducin-like enhancer protein 3 that is encoded in the genome of mouse.


NTF3_MOUSE Neurotrophin-3 (sprot)

A neurotrophin-3 that is encoded in the genome of mouse.


DOK5_MOUSE Docking protein 5 (sprot)

A docking protein 5 that is encoded in the genome of mouse.


name: BCLF1_MOUSE Bcl-2-associated transcription factor 1 (sprot)

description: A Bcl-2-associated transcription factor 1 that is encoded in the genome of mouse.


name: ADA17_MOUSE Disintegrin and metalloproteinase domain-containing protein 17 (sprot)

description: An ADAM 17 endopeptidase that is encoded in the genome of mouse.


name: TLX3_MOUSE T-cell leukemia homeobox protein 3 (sprot)

description: A T-cell leukemia homeobox protein 3 that is encoded in the genome of mouse.


name: TLX1_MOUSE T-cell leukemia homeobox protein 1 (sprot)

description: A T-cell leukemia homeobox protein 1 that is encoded in the genome of mouse.


name: TRI11_MOUSE E3 ubiquitin-protein ligase TRIM11 (sprot)

description: An E3 ubiquitin-protein ligase TRIM11 that is encoded in the genome of mouse.


DYN2_MOUSE Dynamin-2 (sprot)

A dynamin-2 that is encoded in the genome of mouse.


name: CLNK_MOUSE Cytokine-dependent hematopoietic cell linker (sprot)

description: A cytokine-dependent hematopoietic cell linker that is encoded in the genome of mouse.


name: GAB1_MOUSE GRB2-associated-binding protein 1 (sprot)

description: A GRB2-associated-binding protein 1 that is encoded in the genome of mouse.


name: IRS2_MOUSE Insulin receptor substrate 2 (sprot)

description: An insulin receptor substrate 2 that is encoded in the genome of mouse.


name: BCAP_MOUSE Phosphoinositide 3-kinase adapter protein 1 (sprot)

description: A phosphoinositide 3-kinase adapter protein 1 that is encoded in the genome of mouse.


name: GAB2_MOUSE GRB2-associated-binding protein 2 (sprot)

description: A GRB2-associated-binding protein 2 that is encoded in the genome of mouse.


name: TRI41_MOUSE E3 ubiquitin-protein ligase TRIM41 (sprot)

description: An E3 ubiquitin-protein ligase TRIM41 that is encoded in the genome of mouse.


name: GATA2_MOUSE Endothelial transcription factor GATA-2 (sprot)

description: An endothelial transcription factor GATA-2 that is encoded in the genome of mouse.


name: NR1I2_MOUSE Nuclear receptor subfamily 1 group I member 2 (sprot)

description: A nuclear receptor subfamily 1 group I member 2 that is encoded in the genome of mouse.


name: RSBN1_MOUSE Lysine-specific demethylase 9 (sprot)

description: A lysine-specific demethylase 9 that is encoded in the genome of mouse.


name: CISH_MOUSE Cytokine-inducible SH2-containing protein (sprot)

description: A cytokine-inducible SH2-containing protein that is encoded in the genome of mouse.


GARS_MOUSE Glycine--tRNA ligase (sprot)

A glycine--tRNA ligase that is encoded in the genome of mouse.


name: TM11E_MOUSE Transmembrane protease serine 11E (sprot)

description: A transmembrane protease serine 11E that is encoded in the genome of mouse.


name: SLUR1_MOUSE Secreted Ly-6/uPAR-related protein 1 (sprot)

description: A secreted Ly-6/uPAR-related protein 1 that is encoded in the genome of mouse.


name: LCP2_MOUSE Lymphocyte cytosolic protein 2 (sprot)

description: A lymphocyte cytosolic protein 2 that is encoded in the genome of mouse.


name: PK2L1_MOUSE Polycystin-2-like protein 1 (sprot)

description: A polycystin-2-like protein 1 that is encoded in the genome of mouse.


name: MEIKN_MOUSE Meiosis-specific kinetochore protein (sprot)

description: A meiosis-specific kinetochore protein that is encoded in the genome of mouse.


NEUR1_MOUSE Sialidase-1 (sprot)

A sialidase-1 that is encoded in the genome of mouse.


name: SAV1_MOUSE Protein salvador homolog 1 (sprot)

description: A protein salvador homolog 1 that is encoded in the genome of mouse.


synapsin-1 isoform 1b (mouse)

A synapsin-1 isoform 1b that is encoded in the genome of mouse.


name: ERI3_MOUSE ERI1 exoribonuclease 3 (sprot)

description: An ERI1 exoribonuclease 3 that is encoded in the genome of mouse.


name: RAVR2_MOUSE Ribonucleoprotein PTB-binding 2 (sprot)

description: A ribonucleoprotein PTB-binding 2 that is encoded in the genome of mouse.


ZWINT_MOUSE ZW10 interactor (sprot)

A ZW10 interactor that is encoded in the genome of mouse.


CNTN1_MOUSE Contactin-1 (sprot)

A contactin-1 that is encoded in the genome of mouse.


VILI_MOUSE Villin-1 (sprot)

A villin-1 that is encoded in the genome of mouse.


name: GNAI2_MOUSE Guanine nucleotide-binding protein G(i) subunit alpha-2 (sprot)

description: A guanine nucleotide-binding protein G(i) subunit alpha-2 that is encoded in the genome of mouse.


NECT3_MOUSE Nectin-3 (sprot)

A nectin-3 that is encoded in the genome of mouse.


name: GANAB_MOUSE Neutral alpha-glucosidase AB (sprot)

description: A neutral alpha-glucosidase AB that is encoded in the genome of mouse.


name: GMEB1_MOUSE Glucocorticoid modulatory element-binding protein 1 (sprot)

description: A glucocorticoid modulatory element-binding protein 1 that is encoded in the genome of mouse.


VINEX_MOUSE Vinexin (sprot)

A vinexin that is encoded in the genome of mouse.


name: RAP1B_MOUSE Ras-related protein Rap-1b (sprot)

description: A Ras-related protein Rap-1b that is encoded in the genome of mouse.


DOK1_MOUSE Docking protein 1 (sprot)

A docking protein 1 that is encoded in the genome of mouse.


DOK2_MOUSE Docking protein 2 (sprot)

A docking protein 2 that is encoded in the genome of mouse.


name: TNR12_MOUSE Tumor necrosis factor receptor superfamily member 12A (sprot)

description: A tumor necrosis factor receptor superfamily member 12A that is encoded in the genome of mouse.


name: AKIP1_MOUSE A-kinase-interacting protein 1 (sprot)

description: A proline-rich protein BCA3 that is encoded in the genome of mouse.


name: KLF5_MOUSE Krueppel-like factor 5 (sprot)

description: A krueppel-like factor 5 that is encoded in the genome of mouse.


name: STR6L_MOUSE Stimulated by retinoic acid gene 6 protein-like (sprot)

description: A protein that is a translation product of the Stra6l gene in mouse.


TTHY_MOUSE Transthyretin (sprot)

A transthyretin that is encoded in the genome of mouse.


name: STRA6_MOUSE Receptor for retinol uptake STRA6 (sprot)

description: A receptor for retinol uptake STRA6 that is encoded in the genome of mouse.


JARD2_MOUSE Protein Jumonji (sprot)

A protein Jumonji that is encoded in the genome of mouse.


name: ECD_MOUSE Protein ecdysoneless homolog (sprot)

description: A protein ecdysoneless that is encoded in the genome of mouse.


name: PAX2_MOUSE Paired box protein Pax-2 (sprot)

description: A paired box protein Pax-2 that is encoded in the genome of mouse.


name: ICAM2_MOUSE Intercellular adhesion molecule 2 (sprot)

description: An intercellular adhesion molecule 2 that is encoded in the genome of mouse.


name: MRP2_MOUSE ATP-binding cassette sub-family C member 2 (sprot)

description: An ATP-binding cassette sub-family C member 2 that is encoded in the genome of mouse.


name: PUS1_MOUSE Pseudouridylate synthase 1 homolog (sprot)

description: A eukaryotic tRNA pseudouridine synthase A that is encoded in the genome of mouse.


name: GNAT1_MOUSE Guanine nucleotide-binding protein G(t) subunit alpha-1 (sprot)

description: A guanine nucleotide-binding protein G(t) subunit alpha-1 that is encoded in the genome of mouse.


name: RIR1_MOUSE Ribonucleoside-diphosphate reductase large subunit (sprot)

description: A ribonucleoside-diphosphate reductase large subunit that is encoded in the genome of mouse.


name: TGIF1_MOUSE Homeobox protein TGIF1 (sprot)

description: A homeobox protein TGIF1 that is encoded in the genome of mouse.


name: PPARD_MOUSE Peroxisome proliferator-activated receptor delta (sprot)

description: A peroxisome proliferator-activated receptor delta that is encoded in the genome of mouse.


name: CCR8_MOUSE C-C chemokine receptor type 8 (sprot)

description: A C-C chemokine receptor type 8 that is encoded in the genome of mouse.


name: CCR1_MOUSE C-C chemokine receptor type 1 (sprot)

description: A C-C chemokine receptor type 1 that is encoded in the genome of mouse.


name: CCR3_MOUSE Probable C-C chemokine receptor type 3 (sprot)

description: A C-C chemokine receptor type 3 that is encoded in the genome of mouse.


name: ACKR2_MOUSE Atypical chemokine receptor 2 (sprot)

description: An atypical chemokine receptor 2 that is encoded in the genome of mouse.


name: SHCBP_MOUSE SHC SH2 domain-binding protein 1 (sprot)

description: An SHC SH2 domain-binding protein 1 that is encoded in the genome of mouse.


name: SHIP2_MOUSE Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 (sprot)

description: A phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 that is encoded in the genome of mouse.


name: KAT6A_MOUSE Histone acetyltransferase KAT6A (sprot)

description: A histone acetyltransferase KAT6A that is encoded in the genome of mouse.


name: WBP4_MOUSE WW domain-binding protein 4 (sprot)

description: A WW domain-binding protein 4 that is encoded in the genome of mouse.


EQTN_MOUSE Equatorin (sprot)

An equatorin that is encoded in the genome of mouse.


name: ARMX3_MOUSE Armadillo repeat-containing X-linked protein 3 (sprot)

description: An armadillo repeat-containing X-linked protein 3 that is encoded in the genome of mouse.


name: MD12L_MOUSE Mediator of RNA polymerase II transcription subunit 12-like protein (sprot)

description: A mediator of RNA polymerase II transcription subunit 12-like protein that is encoded in the genome of mouse.


name: MED12_MOUSE Mediator of RNA polymerase II transcription subunit 12 (sprot)

description: A mediator of RNA polymerase II transcription subunit 12 that is encoded in the genome of mouse.


name: CENPK_MOUSE Centromere protein K (sprot)

description: A centromere protein K that is encoded in the genome of mouse.


name: DAZP2_MOUSE DAZ-associated protein 2 (sprot)

description: A DAZ-associated protein 2 that is encoded in the genome of mouse.


name: PRRX1_MOUSE Paired mesoderm homeobox protein 1 (sprot)

description: A paired mesoderm homeobox protein 1 that is encoded in the genome of mouse.


name: SPTA1_MOUSE Spectrin alpha chain, erythrocytic 1 (sprot)

description: A spectrin alpha chain, erythrocytic 1 that is encoded in the genome of mouse.


ANXA7_MOUSE Annexin A7 (sprot)

An annexin A7 that is encoded in the genome of mouse.


name: ARHG5_MOUSE Rho guanine nucleotide exchange factor 5 (sprot)

description: A Rho guanine nucleotide exchange factor 5 that is encoded in the genome of mouse.


name: RND2_MOUSE Rho-related GTP-binding protein RhoN (sprot)

description: A Rho-related GTP-binding protein RhoN that is encoded in the genome of mouse.


name: PLD4_MOUSE 5'-3' exonuclease PLD4 (sprot)

description: A 5'-3' exonuclease PLD4 that is encoded in the genome of mouse.


STMN3_MOUSE Stathmin-3 (sprot)

A stathmin-3 that is encoded in the genome of mouse.


SNG3_MOUSE Synaptogyrin-3 (sprot)

A synaptogyrin-3 that is encoded in the genome of mouse.


name: SCAM1_MOUSE Secretory carrier-associated membrane protein 1 (sprot)

description: A secretory carrier-associated membrane protein 1 that is encoded in the genome of mouse.


ARFP2_MOUSE Arfaptin-2 (sprot)

An arfaptin-2 that is encoded in the genome of mouse.


name: MAF_MOUSE Transcription factor Maf (sprot)

description: A transcription factor Maf that is encoded in the genome of mouse.


name: TRI27_MOUSE Zinc finger protein RFP (sprot)

description: A zinc finger protein RFP that is encoded in the genome of mouse.


name: SBNO2_MOUSE Protein strawberry notch homolog 2 (sprot)

description: A protein strawberry notch homolog 2 that is encoded in the genome of mouse.


name: CNDG2_MOUSE Condensin-2 complex subunit G2 (sprot)

description: A condensin-2 complex subunit G2 that is encoded in the genome of mouse.


BOC_MOUSE Brother of CDO (sprot)

A brother of CDO that is encoded in the genome of mouse.


GPC3_MOUSE Glypican-3 (sprot)

A glypican-3 that is encoded in the genome of mouse.


name: SCX_MOUSE Basic helix-loop-helix transcription factor scleraxis (sprot)

description: A basic helix-loop-helix transcription factor scleraxis that is encoded in the genome of mouse.


name: ASCL3_MOUSE Achaete-scute homolog 3 (sprot)

description: An achaete-scute homolog 3 that is encoded in the genome of mouse.


name: TWST1_MOUSE Twist-related protein 1 (sprot)

description: A twist-related protein 1 that is encoded in the genome of mouse.


name: ATOH1_MOUSE Transcription factor Atoh1 (sprot)

description: A transcription factor ATOH1 that is encoded in the genome of mouse.


name: ASH2L_MOUSE Set1/Ash2 histone methyltransferase complex subunit ASH2 (sprot)

description: A Set1/Ash2 histone methyltransferase complex subunit ASH2 that is encoded in the genome of mouse.


name: OX2R_MOUSE Orexin receptor type 2 (sprot)

description: An orexin receptor type 2 that is encoded in the genome of mouse.


name: GDF3_MOUSE Growth/differentiation factor 3 (sprot)

description: A growth/differentiation factor 3 that is encoded in the genome of mouse.


name: NHRF2_MOUSE Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (sprot)

description: A Na(+)/H(+) exchange regulatory cofactor NHE-RF2 that is encoded in the genome of mouse.


name: TEF_MOUSE Thyrotroph embryonic factor (sprot)

description: A thyrotroph embryonic factor that is encoded in the genome of mouse.


PGS1_MOUSE Biglycan (sprot)

A biglycan that is encoded in the genome of mouse.


name: NREP_MOUSE Neuronal regeneration-related protein (sprot)

description: A neuronal regeneration-related protein that is encoded in the genome of mouse.


name: ACVL1_MOUSE Serine/threonine-protein kinase receptor R3 (sprot)

description: A serine/threonine-protein kinase receptor R3 that is encoded in the genome of mouse.


name: C1D_MOUSE Nuclear nucleic acid-binding protein C1D (sprot)

description: A nuclear nucleic acid-binding protein C1D that is encoded in the genome of mouse.


name: MRTFA_MOUSE Myocardin-related transcription factor A (sprot)

description: A myocardin-related transcription factor A that is encoded in the genome of mouse.


name: MRTFB_MOUSE Myocardin-related transcription factor B (sprot)

description: A myocardin-related transcription factor B that is encoded in the genome of mouse.


TYRO_MOUSE Tyrosinase (sprot)

A tyrosinase that is encoded in the genome of mouse.


name: ANKR1_MOUSE Ankyrin repeat domain-containing protein 1 (sprot)

description: An ankyrin repeat domain-containing protein 1 that is encoded in the genome of mouse.


name: CIDEA_MOUSE Lipid transferase CIDEA (sprot)

description: A lipid transferase CIDEA that is encoded in the genome of mouse.


name: PTPRS_MOUSE Receptor-type tyrosine-protein phosphatase S (sprot)

description: A receptor-type tyrosine-protein phosphatase S that is encoded in the genome of mouse.


name: PORCN_MOUSE Protein-serine O-palmitoleoyltransferase porcupine (sprot)

description: A protein-serine O-palmitoleoyltransferase porcupine that is encoded in the genome of mouse.


name: PPIF_MOUSE Peptidyl-prolyl cis-trans isomerase F, mitochondrial (sprot)

description: A peptidyl-prolyl cis-trans isomerase F, mitochondrial that is encoded in the genome of mouse.


name: SFRP3_MOUSE Secreted frizzled-related protein 3 (sprot)

description: A secreted frizzled-related protein 3 that is encoded in the genome of mouse.


name: YAF2_MOUSE YY1-associated factor 2 (sprot)

description: A YY1-associated factor 2 that is encoded in the genome of mouse.


name: BT1A1_MOUSE Butyrophilin subfamily 1 member A1 (sprot)

description: A butyrophilin subfamily 1 member A1 that is encoded in the genome of mouse.


name: B4GT1_MOUSE Beta-1,4-galactosyltransferase 1 (sprot)

description: A beta-1,4-galactosyltransferase 1 that is encoded in the genome of mouse.


name: ZP3R_MOUSE Zona pellucida sperm-binding protein 3 receptor (sprot)

description: A zona pellucida sperm-binding protein 3 receptor that is encoded in the genome of mouse.


name: NFU1_MOUSE NFU1 iron-sulfur cluster scaffold homolog, mitochondrial (sprot)

description: An NFU1 iron-sulfur cluster scaffold, mitochondrial that is encoded in the genome of mouse.


PKHD1_MOUSE Fibrocystin (sprot)

A fibrocystin that is encoded in the genome of mouse.


name: TJAP1_MOUSE Tight junction-associated protein 1 (sprot)

description: A tight junction-associated protein 1 that is encoded in the genome of mouse.


name: TGFB2_MOUSE Transforming growth factor beta-2 proprotein (sprot)

description: A TGF-beta 2 that is encoded in the genome of mouse.


name: ATRN1_MOUSE Attractin-like protein 1 (sprot)

description: An attractin-like protein 1 that is encoded in the genome of mouse.


name: AT8B2_MOUSE Phospholipid-transporting ATPase ID (sprot)

description: A phospholipid-transporting ATPase ID that is encoded in the genome of mouse.


GAST_MOUSE Gastrin (sprot)

A gastrin that is encoded in the genome of mouse.


CCKN_MOUSE Cholecystokinin (sprot)

A cholecystokinin that is encoded in the genome of mouse.


name: BAG4_MOUSE BAG family molecular chaperone regulator 4 (sprot)

description: A BAG family molecular chaperone regulator 4 that is encoded in the genome of mouse.


name: DJB11_MOUSE DnaJ homolog subfamily B member 11 (sprot)

description: A DnaJ homolog subfamily B member 11 that is encoded in the genome of mouse.


name: AT12A_MOUSE Potassium-transporting ATPase alpha chain 2 (sprot)

description: A potassium-transporting ATPase alpha chain 2 that is encoded in the genome of mouse.


name: FCRL6_MOUSE Fc receptor-like protein 6 (sprot)

description: A protein that is a translation product of the Fcrl6 gene in mouse.


name: VTCN1_MOUSE V-set domain containing T-cell activation inhibitor 1 (sprot)

description: A V-set domain-containing T-cell activation inhibitor 1 that is encoded in the genome of mouse.


name: IGHM_MOUSE Immunoglobulin heavy constant mu (sprot)

description: An immunoglobulin heavy constant mu that is encoded in the genome of mouse.


name: PPIC_MOUSE Peptidyl-prolyl cis-trans isomerase C (sprot)

description: A eukaryotic-type peptidyl-prolyl cis-trans isomerase C that is encoded in the genome of mouse.


name: SODE_MOUSE Extracellular superoxide dismutase [Cu-Zn] (sprot)

description: An extracellular superoxide dismutase [Cu-Zn] that is encoded in the genome of mouse.


VWF_MOUSE von Willebrand factor (sprot)

A von Willebrand factor that is encoded in the genome of mouse.


name: KLF15_MOUSE Krueppel-like factor 15 (sprot)

description: A krueppel-like factor 15 that is encoded in the genome of mouse.


name: SPTC1_MOUSE Serine palmitoyltransferase 1 (sprot)

description: A serine palmitoyltransferase 1 that is encoded in the genome of mouse.


EFNB2_MOUSE Ephrin-B2 (sprot)

An ephrin-B2 that is encoded in the genome of mouse.


name: EPHB4_MOUSE Ephrin type-B receptor 4 (sprot)

description: An ephrin type-B receptor 4 that is encoded in the genome of mouse.


name: S35D3_MOUSE Solute carrier family 35 member D3 (sprot)

description: A solute carrier family 35 member D3 that is encoded in the genome of mouse.


name: NCK1_MOUSE SH2/SH3 adapter protein Nck1 (sprot)

description: An SH2/SH3 adapter protein NCK1 that is encoded in the genome of mouse.


EFNA5_MOUSE Ephrin-A5 (sprot)

An ephrin-A5 that is encoded in the genome of mouse.


name: DPOA2_MOUSE DNA polymerase alpha subunit B (sprot)

description: A DNA polymerase alpha subunit B that is encoded in the genome of mouse.


name: SELPL_MOUSE P-selectin glycoprotein ligand 1 (sprot)

description: A P-selectin glycoprotein ligand 1 that is encoded in the genome of mouse.


STON2_MOUSE Stonin-2 (sprot)

A stonin-2 that is encoded in the genome of mouse.


RIC8A_MOUSE Synembryn-A (sprot)

A synembryn-A that is encoded in the genome of mouse.


name: PR domain zinc finger protein 1 isoform 2 (mouse)

description: A PR domain zinc finger protein 1 isoform 2 that is encoded in the genome of mouse.


name: DPOLA_MOUSE DNA polymerase alpha catalytic subunit (sprot)

description: A DNA polymerase alpha catalytic subunit that is encoded in the genome of mouse.


name: FKB1B_MOUSE Peptidyl-prolyl cis-trans isomerase FKBP1B (sprot)

description: A peptidyl-prolyl cis-trans isomerase FKBP1B that is encoded in the genome of mouse.


NID1_MOUSE Nidogen-1 (sprot)

A nidogen-1 that is encoded in the genome of mouse.


name: WWOX_MOUSE WW domain-containing oxidoreductase (sprot)

description: A WW domain-containing oxidoreductase that is encoded in the genome of mouse.


name: SAA2_MOUSE Serum amyloid A-2 protein (sprot)

description: A murine-type serum amyloid A-2 protein that is encoded in the genome of mouse.


name: SAA1_MOUSE Serum amyloid A-1 protein (sprot)

description: A murine-type serum amyloid A-1 protein that is encoded in the genome of mouse.


name: TINAL_MOUSE Tubulointerstitial nephritis antigen-like (sprot)

description: A tubulointerstitial nephritis antigen-like that is encoded in the genome of mouse.


NSF1C_MOUSE NSFL1 cofactor p47 (sprot)

An NSFL1 cofactor p47 that is encoded in the genome of mouse.


FBX6_MOUSE F-box only protein 6 (sprot)

An F-box only protein 6 that is encoded in the genome of mouse.


ATX3_MOUSE Ataxin-3 (sprot)

An ataxin-3 that is encoded in the genome of mouse.


name: ZFN2B_MOUSE AN1-type zinc finger protein 2B (sprot)

description: An AN1-type zinc finger protein 2B that is encoded in the genome of mouse.


name: BACH2_MOUSE Transcription regulator protein BACH2 (sprot)

description: A transcription regulator protein BACH2 that is encoded in the genome of mouse.


name: BACH1_MOUSE Transcription regulator protein BACH1 (sprot)

description: A transcription regulator protein BACH1 that is encoded in the genome of mouse.


cell migration

category: biolink:BiologicalProcess biolink:Occurrent biolink:OntologyClass biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: The controlled self-propelled movement of a cell from one site to a destination guided by molecular cues.


mesendoderm development

description: The process whose specific outcome is the progression of the mesendoderm over time, from its formation to the mature structure. In animal embryos, mesendoderm development gives rise to both mesoderm and endoderm tissues.


name: RNA polymerase II transcription regulatory region sequence-specific DNA binding

category: biolink:MolecularActivity biolink:Occurrent biolink:OntologyClass biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: Binding to a specific sequence of DNA that is part of a regulatory region that controls the transcription of a gene or cistron by RNA polymerase II.


cranial skeletal system development

description: The process whose specific outcome is the progression of a cranial skeletal system over time, from its formation to the mature structure. The cranial skeletal system is the skeletal subdivision of the head, and includes the skull (cranium plus mandible), pharyngeal and/or hyoid apparatus.


mRNA metabolic process

description: The chemical reactions and pathways involving mRNA, messenger RNA, which is responsible for carrying the coded genetic 'message', transcribed from DNA, to sites of protein assembly at the ribosomes.


heparin binding

description: Binding to heparin, a member of a group of glycosaminoglycans found mainly as an intracellular component of mast cells and which consist predominantly of alternating alpha-(1->4)-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues.


intermediate filament organization

description: Control of the spatial distribution of intermediate filaments; includes organizing filaments into meshworks, bundles, or other structures, as by cross-linking.


name: positive regulation of non-canonical NF-kappaB signal transduction

description: Any process that activates or increases the frequency, rate or extent of the non-canonical NF-kappaB cascade.


protein-containing complex localization

description: A localization process that acts on a protein complex; the complex is transported to, or maintained in, a specific location.


SMAD protein signal transduction

category: biolink:Pathway biolink:OntologyClass biolink:BiologicalProcess biolink:Occurrent biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: An intracellular signaling cassette that starts with the activation of a SMAD protein, leading to the formation of a complex with co-SMADs, which translocates to the nucleus and regulates transcription of specific target genes.


epithelial structure maintenance

description: A tissue homeostatic process required for the maintenance of epithelial structure.


actin filament polymerization

description: Assembly of actin filaments by the addition of actin monomers to a filament.


contact inhibition

description: The series of events in which information about the density of cells in a population is received by direct cell-cell contact and is converted into a molecular signal, resulting in the cessation of cell growth or proliferation.


cAMP response element binding

description: Binding to a cyclic AMP response element (CRE), a short palindrome-containing sequence found in the promoters of genes whose expression is regulated in response to cyclic AMP.


name: negative regulation of canonical NF-kappaB signal transduction

description: Any process that stops, prevents, or reduces the frequency, rate or extent of a canonical NF-kappaB signaling cascade.


epithelial to mesenchymal transition

description: A transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.


name: Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform m2 (mouse)

description: An Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9QWY8-2.


name: Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform m1 (mouse)

description: An Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9QWY8-1.


MMRN2_HUMAN Multimerin-2 (sprot)

A multimerin-2 that is encoded in the genome of human.


name: mothers against decapentaplegic homolog 7 isoform A monomethylated 1 (mouse)

description: A mothers against decapentaplegic homolog 7 isoform A (mouse) that has been monomethylated at the position equivalent to Lys-70. UniProtKB:O35253-1, Lys-70, MOD:00085.


MCLN1_HUMAN Mucolipin-1 (sprot)

A mucolipin-1 that is encoded in the genome of human.


name: TM163_HUMAN Transmembrane protein 163 (sprot)

description: A transmembrane protein 163 that is encoded in the genome of human.


MCLN2_HUMAN Mucolipin-2 (sprot)

A mucolipin-2 that is encoded in the genome of human.


name: T176A_HUMAN Transmembrane protein 176A (sprot)

description: A transmembrane protein 176A that is encoded in the genome of human.


name: IFT88_HUMAN Intraflagellar transport protein 88 homolog (sprot)

description: An intraflagellar transport protein 88 that is encoded in the genome of human.


name: KATIP_HUMAN Katanin-interacting protein (sprot)

description: A katanin-interacting protein that is encoded in the genome of human.


name: KTBL1_HUMAN KATNB1-like protein 1 (sprot)

description: A KATNB1-like protein 1 that is encoded in the genome of human.


name: YTDC1_HUMAN YTH domain-containing protein 1 (sprot)

description: A YTH domain-containing protein 1 that is encoded in the genome of human.


name: SRSF7_HUMAN Serine/arginine-rich splicing factor 7 (sprot)

description: A serine/arginine-rich splicing factor 7 that is encoded in the genome of human.


name: SRSF3_HUMAN Serine/arginine-rich splicing factor 3 (sprot)

description: A serine/arginine-rich splicing factor 3 that is encoded in the genome of human.


name: CPSF6_HUMAN Cleavage and polyadenylation specificity factor subunit 6 (sprot)

description: A cleavage and polyadenylation specificity factor subunit 6 that is encoded in the genome of human.


name: sarcoplasmic/endoplasmic reticulum calcium ATPase 2 isoform 1 (mouse)

description: A sarcoplasmic/endoplasmic reticulum calcium ATPase 2 isoform 1 that is encoded in the genome of mouse.


name: IFT27_HUMAN Intraflagellar transport protein 27 homolog (sprot)

description: An intraflagellar transport protein 27 homolog that is encoded in the genome of human.


name: IFT20_HUMAN Intraflagellar transport protein 20 homolog (sprot)

description: An intraflagellar transport protein 20 that is encoded in the genome of human.


name: IFT74_HUMAN Intraflagellar transport protein 74 homolog (sprot)

description: An intraflagellar transport protein 74 that is encoded in the genome of human.


name: MIPT3_HUMAN TRAF3-interacting protein 1 (sprot)

description: A TRAF3-interacting protein 1 that is encoded in the genome of human.


name: IFT81_HUMAN Intraflagellar transport protein 81 homolog (sprot)

description: An intraflagellar transport protein 81 that is encoded in the genome of human.


name: IFT46_HUMAN Intraflagellar transport protein 46 homolog (sprot)

description: An intraflagellar transport protein 46 homolog that is encoded in the genome of human.


name: IFT52_HUMAN Intraflagellar transport protein 52 homolog (sprot)

description: An intraflagellar transport protein 52 that is encoded in the genome of human.


name: IFT80_HUMAN Intraflagellar transport protein 80 homolog (sprot)

description: An intraflagellar transport protein 80 that is encoded in the genome of human.


name: IFT57_HUMAN Intraflagellar transport protein 57 homolog (sprot)

description: An intraflagellar transport protein 57 that is encoded in the genome of human.


name: IF172_HUMAN Intraflagellar transport protein 172 homolog (sprot)

description: An intraflagellar transport protein 172 that is encoded in the genome of human.


name: IFT25_HUMAN Intraflagellar transport protein 25 homolog (sprot)

description: An intraflagellar transport protein 25 homolog that is encoded in the genome of human.


name: WDR47_HUMAN WD repeat-containing protein 47 (sprot)

description: A WD repeat-containing protein 47 that is encoded in the genome of human.


STMN2_HUMAN Stathmin-2 (sprot)

A stathmin-2 that is encoded in the genome of human.


name: KCNJ1_HUMAN ATP-sensitive inward rectifier potassium channel 1 (sprot)

description: An ATP-sensitive inward rectifier potassium channel 1 that is encoded in the genome of human.


CALX_HUMAN Calnexin (sprot)

A calnexin that is encoded in the genome of human.


name: TMTC4_HUMAN Protein O-mannosyl-transferase TMTC4 (sprot)

description: A protein O-mannosyl-transferase TMTC4 that is encoded in the genome of human.


name: AT2A2_HUMAN Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (sprot)

description: A sarcoplasmic/endoplasmic reticulum calcium ATPase 2 that is encoded in the genome of human.


name: GBRL2_HUMAN Gamma-aminobutyric acid receptor-associated protein-like 2 (sprot)

description: A gamma-aminobutyric acid receptor-associated protein-like 2 that is encoded in the genome of human.


name: MLP3C_HUMAN Microtubule-associated proteins 1A/1B light chain 3C (sprot)

description: A microtubule-associated proteins 1A/1B light chain 3C that is encoded in the genome of human.


name: RETR1_HUMAN Reticulophagy regulator 1 (sprot)

description: A reticulophagy regulator 1 that is encoded in the genome of human.


name: TX264_HUMAN Testis-expressed protein 264 (sprot)

description: A testis-expressed protein 264 that is encoded in the genome of human.


name: GBRAP_HUMAN Gamma-aminobutyric acid receptor-associated protein (sprot)

description: A gamma-aminobutyric acid receptor-associated protein that is encoded in the genome of human.


name: CCPG1_HUMAN Cell cycle progression protein 1 (sprot)

description: A cell cycle progression protein 1 that is encoded in the genome of human.


name: MLP3A_HUMAN Microtubule-associated proteins 1A/1B light chain 3A (sprot)

description: A microtubule-associated proteins 1A/1B light chain 3A that is encoded in the genome of human.


name: GBRL1_HUMAN Gamma-aminobutyric acid receptor-associated protein-like 1 (sprot)

description: A gamma-aminobutyric acid receptor-associated protein-like 1 that is encoded in the genome of human.


usherin isoform m3 (mouse)

An usherin (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q2QI47-3.


name: ITPR1_HUMAN Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1 (sprot)

description: An inositol 1,4,5-trisphosphate receptor type 1 that is encoded in the genome of human.


name: ITPR3_HUMAN Inositol 1,4,5-trisphosphate receptor type 3 (sprot)

description: An inositol 1,4,5-trisphosphate receptor type 3 that is encoded in the genome of human.


name: ITPR2_HUMAN Inositol 1,4,5-trisphosphate receptor type 2 (sprot)

description: An inositol 1,4,5-trisphosphate receptor type 2 that is encoded in the genome of human.


name: PROP1_PIG Homeobox protein prophet of Pit-1 (sprot)


name: EAA3_HUMAN Excitatory amino acid transporter 3 (sprot)

description: An excitatory amino acid transporter 3 that is encoded in the genome of human.


name: NPC2_HUMAN NPC intracellular cholesterol transporter 2 (sprot)

description: An NPC intracellular cholesterol transporter 2 that is encoded in the genome of human.


name: HAVR2_HUMAN Hepatitis A virus cellular receptor 2 (sprot)

description: A hepatitis A virus cellular receptor 2 that is encoded in the genome of human.


name: LRRK2_HUMAN Leucine-rich repeat serine/threonine-protein kinase 2 (sprot)

description: A leucine-rich repeat serine/threonine-protein kinase 2 that is encoded in the genome of human.


name: DNA-dependent protein kinase catalytic subunit isoform h1 (human)

description: A DNA-dependent protein kinase catalytic subunit (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P78527-1.


H31_HUMAN Histone H3.1 (sprot)

A histone H3 that is a translation product of any of the following genes in human: HIST1H3A/HIST1H3B/HIST1H3C/HIST1H3D/HIST1H3E/HIST1H3F/HIST1H3G/HIST1H3H/HIST1H3I/HIST1H3J.


COR1C_HUMAN Coronin-1C (sprot)

A coronin-1C that is encoded in the genome of human.


S100B_HUMAN Protein S100-B (sprot)

A protein S100-B that is encoded in the genome of human.


S10A2_HUMAN Protein S100-A2 (sprot)

A protein S100-A2 that is encoded in the genome of human.


S10A6_HUMAN Protein S100-A6 (sprot)

A protein S100-A6 that is encoded in the genome of human.


name: SOX4_HUMAN Transcription factor SOX-4 (sprot)

description: A transcription factor SOX-4 that is encoded in the genome of human.


name: PI4KB_HUMAN Phosphatidylinositol 4-kinase beta (sprot)

description: A phosphatidylinositol 4-kinase beta that is encoded in the genome of human.


name: MPRI_HUMAN Cation-independent mannose-6-phosphate receptor (sprot)

description: A cation-independent mannose-6-phosphate receptor that is encoded in the genome of human.


name: EPHB2_HUMAN Ephrin type-B receptor 2 (sprot)

description: An ephrin type-B receptor 2 that is encoded in the genome of human.


name: P53_HUMAN Cellular tumor antigen p53 (sprot)

description: A cellular tumor antigen p53 that is encoded in the genome of human.


name: RHDF1_HUMAN Inactive rhomboid protein 1 (sprot)

description: An inactive rhomboid protein 1 that is encoded in the genome of human.


name: ADA17_HUMAN Disintegrin and metalloproteinase domain-containing protein 17 (sprot)

description: An ADAM 17 endopeptidase that is encoded in the genome of human.


name: PCBP2_HUMAN Poly(rC)-binding protein 2 (sprot)

description: A poly(rC)-binding protein 2 that is encoded in the genome of human.


name: GPVI_HUMAN Platelet glycoprotein VI (sprot)

description: A platelet glycoprotein VI that is encoded in the genome of human.


name: TIFA_HUMAN TRAF-interacting protein with FHA domain-containing protein A (sprot)

description: A TRAF-interacting protein with FHA domain-containing protein A that is encoded in the genome of human.


name: IP6K2_HUMAN Inositol hexakisphosphate kinase 2 (sprot)

description: An inositol hexakisphosphate kinase 2 that is encoded in the genome of human.


name: ORAI1_HUMAN Calcium release-activated calcium channel protein 1 (sprot)

description: A calcium release-activated calcium channel protein 1 that is encoded in the genome of human.


name: retinoblastoma-binding protein 5 isoform h2 (human)

description: A retinoblastoma-binding protein 5 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q15291-2.


name: IRF1_HUMAN Interferon regulatory factor 1 (sprot)

description: An interferon regulatory factor 1 that is encoded in the genome of human.


name: IRF2_HUMAN Interferon regulatory factor 2 (sprot)

description: An interferon regulatory factor 2 that is encoded in the genome of human.


name: RHG27_MOUSE Rho GTPase-activating protein 27 (sprot)

description: A Rho GTPase-activating protein 27 that is encoded in the genome of mouse.


formin-1 isoform 5 (mouse)

A formin-1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q05860-5.


formin-1 isoform 6 (mouse)

A formin-1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q05860-6.


syntaxin-3B phosphorylated 1 (mouse)

A syntaxin-3B (mouse) that has been phosphorylated on Thr-14. UniProtKB:Q64704-2, Thr-14, MOD:00047.


name: vascular endothelial growth factor A, long form isoform 2 (mouse)

description: A vascular endothelial growth factor A, long form isoform 2 that is encoded in the genome of mouse.


name: microsomal triglyceride transfer protein large subunit isoform 1 (mouse)

description: A microsomal triglyceride transfer protein large subunit isoform 1 that is encoded in the genome of mouse.


name: microsomal triglyceride transfer protein large subunit isoform 2 (mouse)

description: A microsomal triglyceride transfer protein large subunit isoform 2 that is encoded in the genome of mouse.


name: vascular endothelial growth factor C isoform 1 (mouse)

description: A vascular endothelial growth factor C isoform 1 that is encoded in the genome of mouse.


DNA ligase 3 isoform Alpha (mouse)

A DNA ligase 3 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P97386-1.


name: PAPOB_MOUSE Poly(A) polymerase beta (sprot)

description: A poly(A) polymerase beta that is encoded in the genome of mouse.


name: small ubiquitin-related modifier 1 isoform 1 (mouse)

description: A small ubiquitin-related modifier 1 isoform 1 that is encoded in the genome of mouse.


name: serine/threonine-protein kinase LMTK1 isoform 2 palmitoylated 1 (mouse)

description: A serine/threonine-protein kinase LMTK1 isoform 2 palmitoylated 1 in mouse. UniProtKB:Q80YE4-2, Cys-4/Cys-6/Cys-7, MOD:00115.


name: serine/threonine-protein kinase LMTK1 isoform 2 (mouse)

description: A serine/threonine-protein kinase LMTK1 isoform 2 that is encoded in the genome of mouse.


name: zinc finger protein Eos isoform 2 (mouse)

description: A zinc finger protein Eos isoform 2 that is encoded in the genome of mouse.


name: suppressor of fused homolog isoform 1 (mouse)

description: A suppressor of fused homolog isoform 1 that is encoded in the genome of mouse.


name: suppressor of fused homolog isoform 4 (mouse)

description: A suppressor of fused homolog isoform 4 that is encoded in the genome of mouse.


name: TRXR2_MOUSE Thioredoxin reductase 2, mitochondrial (sprot)

description: A thioredoxin reductase 2, mitochondrial that is encoded in the genome of mouse.


name: elongator complex protein 2 isoform 1 (mouse)

description: An elongator complex protein 2 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q91WG4-1.


name: forkhead box protein O1 isoform 1 (mouse)

description: A forkhead box protein O1 isoform 1 that is encoded in the genome of mouse.


name: Q9CYE0_MOUSE Ankyrin repeat domain-containing protein 24 (trembl)

description: An ankyrin repeat domain-containing protein 24 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9CYE0.


name: centrosomal protein POC5 isoform m1 (mouse)

description: A centrosomal protein POC5 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9DBS8-1.


name: GSTCD_MOUSE Glutathione S-transferase C-terminal domain-containing protein (sprot)

description: A glutathione S-transferase C-terminal domain-containing protein that is encoded in the genome of mouse.


name: MCRI2_MOUSE MAPK regulated corepressor interacting protein 2 (sprot)

description: A MAPK regulated corepressor interacting protein 2 that is encoded in the genome of mouse.


name: pachytene checkpoint protein 2 homolog isoform 1 (mouse)

description: A thyroid receptor-interacting protein 13 isoform 1 that is encoded in the genome of mouse.


name: CEP89_MOUSE Centrosomal protein of 89 kDa (sprot)

description: A centrosomal protein of 89 kDa that is encoded in the genome of mouse.


Q80XD5_MOUSE Fryl protein (trembl)

A Fryl gene translation product (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q80XD5.


interleukin-24 isoform 1 (mouse)

An interleukin-24 isoform 1 that is encoded in the genome of mouse.


name: ERI1 exoribonuclease 3 isoform 1 (mouse)

description: An ERI1 exoribonuclease 3 isoform 1 that is encoded in the genome of mouse.


name: RNA-binding protein 39 isoform 2 (mouse)

description: An RNA-binding protein 39 isoform 2 that is encoded in the genome of mouse.


name: interleukin-17 receptor C isoform 1 (mouse)

description: An interleukin-17 receptor C (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8K4C2-1.


name: disrupted in schizophrenia 1 protein isoform 1 phosphorylated 1 (mouse)

description: A disrupted in schizophrenia 1 protein isoform 1 phosphorylated 1 in mouse. UniProtKB:Q811T9-1, Ser-710, MOD:00046.


name: disrupted in schizophrenia 1 protein isoform 1 unphosphorylated form (mouse)

description: A disrupted in schizophrenia 1 protein isoform 1 unphosphorylated form in mouse.


name: RAC-alpha serine/threonine-protein kinase phosphorylated 1 (mouse)

description: A RAC-alpha serine/threonine-protein kinase (mouse) that has been phosphorylated on the residue at the position equivalent to Thr-308, and phosphoserine at position 473 of the amino acid sequence represented by UniProtKB:P31750. UniProtKB:P31750, Thr-308, MOD:00047|Ser-473, MOD:00046.


name: DWORF_MOUSE Sarcoplasmic/endoplasmic reticulum calcium ATPase regulator DWORF (sprot)

description: A protein that is a translation product of the Gm34302 gene in mouse.


name: Q8K0M3_MOUSE Sorbin and SH3 domain containing 3 (trembl)

description: A vinexin (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8K0M3.


BTG1_MOUSE Protein BTG1 (sprot)

A protein BTG1 that is encoded in the genome of mouse.


name: CD3G_MOUSE T-cell surface glycoprotein CD3 gamma chain (sprot)

description: A CD3 gamma that is encoded in the genome of mouse.


name: LIM domain-binding protein 2 isoform 2 (mouse)

description: A LIM domain-binding protein 2 isoform 2 that is encoded in the genome of mouse.


name: M-phase inducer phosphatase 2 phosphorylated 2 (mouse)

description: An M-phase inducer phosphatase 2 (mouse) that has been phosphorylated on the residue at the position equivalent to Ser-321 of the amino acid sequence represented by UniProtKB:P30306. UniProtKB:P30306, Ser-321, MOD:00046.


name: ATP-dependent 6-phosphofructokinase, muscle type isoform 1 (mouse)

description: An ATP-dependent 6-phosphofructokinase, muscle type isoform 1 that is encoded in the genome of mouse.


name: SIK2_HUMAN Serine/threonine-protein kinase SIK2 (sprot)

description: A serine/threonine-protein kinase SIK2 that is encoded in the genome of human.


name: TGM2_HUMAN Protein-glutamine gamma-glutamyltransferase 2 (sprot)

description: A protein-glutamine gamma-glutamyltransferase 2 that is encoded in the genome of human.


name: IMA3_HUMAN Importin subunit alpha-3 (sprot)

description: An importin subunit alpha-3 that is encoded in the genome of human.


name: AAPK2_HUMAN 5'-AMP-activated protein kinase catalytic subunit alpha-2 (sprot)

description: A 5'-AMP-activated protein kinase catalytic subunit alpha-2 that is encoded in the genome of human.


name: AAPK1_HUMAN 5'-AMP-activated protein kinase catalytic subunit alpha-1 (sprot)

description: A 5'-AMP-activated protein kinase catalytic subunit alpha-1 that is encoded in the genome of human.


name: PIAS4_HUMAN E3 SUMO-protein ligase PIAS4 (sprot)

description: An E3 SUMO-protein ligase PIAS4 that is encoded in the genome of human.


name: SENP3_HUMAN Sentrin-specific protease 3 (sprot)

description: A sentrin-specific protease 3 that is encoded in the genome of human.


name: RN186_HUMAN E3 ubiquitin-protein ligase RNF186 (sprot)

description: An E3 ubiquitin-protein ligase RNF186 that is encoded in the genome of human.


EFNB1_HUMAN Ephrin-B1 (sprot)

An ephrin-B1 that is encoded in the genome of human.


name: proton-transporting V-type ATPase, V1 domain

category: biolink:CellularComponent biolink:AnatomicalEntity biolink:PhysicalEssence biolink:OrganismalEntity biolink:SubjectOfInvestigation biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: A protein complex that forms part of a proton-transporting V-type ATPase and catalyzes ATP hydrolysis. The V1 complex consists of: (1) a globular headpiece with three alternating copies of subunits A and B that form a ring, (2) a central rotational stalk composed of single copies of subunits D and F, and (3) a peripheral stalk made of subunits C, E, G and H. Subunits A and B mediate the hydrolysis of ATP at three reaction sites associated with subunit A.


name: proton-transporting V-type ATPase complex

description: A proton-transporting two-sector ATPase complex that couples ATP hydrolysis to the transport of protons across a concentration gradient. The resulting transmembrane electrochemical potential of H+ is used to drive a variety of (i) secondary active transport systems via H+-dependent symporters and antiporters and (ii) channel-mediated transport systems. The complex comprises a membrane sector (V0) that carries out proton transport and a cytoplasmic compartment sector (V1) that catalyzes ATP hydrolysis. V-type ATPases are found in the membranes of organelles such as vacuoles, endosomes, and lysosomes, and in the plasma membrane.


sprouting angiogenesis

description: The extension of new blood vessels from existing vessels into avascular tissues, this process includes the specialization of endothelial cells into leading tip and stalk cells, proliferation and migration of the endothelial cells and cell adhesion resulting in angiogenic sprout fusion or lumen formation.


name: negative regulation of DNA-binding transcription factor activity

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of a transcription factor, any factor involved in the initiation or regulation of transcription.


name: regulation of hyaluronan biosynthetic process

description: Any process that modulates the frequency, rate or extent of hyaluronan biosynthetic process.


endocardium development

description: The process whose specific outcome is the progression of the endocardium over time, from its formation to the mature structure. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers.


future forebrain

category: biolink:AnatomicalEntity biolink:PhysicalEssence biolink:OrganismalEntity biolink:SubjectOfInvestigation biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: A presumptive structure that has the potential to develop into a forebrain.


antibacterial innate immune response

description: An defense response against a bacteria mediated through an innate immune response. An innate immune response is mediated by germline encoded components that directly recognize components of potential pathogens.


name: defense response to Gram-negative bacterium

description: Reactions triggered in response to the presence of a Gram-negative bacterium that act to protect the cell or organism.


positive regulation of gene expression

description: Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA).


mitochondrial unfolded protein response

description: The series of molecular signals generated as a consequence of the presence of unfolded proteins in the mitochondrial matrix; results in transcriptional upregulation of nuclear genes encoding mitochondrial stress proteins.


BMP signaling pathway

description: The series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.


name: skeletal muscle satellite cell differentiation

description: The process in which a relatively unspecialized cell acquires specialized features of a satellite cell.


skeletal muscle cell differentiation

description: The process in which a relatively unspecialized cell acquires specialized features of a skeletal muscle cell, a somatic cell located in skeletal muscle.


name: negative regulation of intrinsic apoptotic signaling pathway

description: Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway.


name: endoplasmic reticulum unfolded protein response

description: The series of molecular signals generated as a consequence of the presence of unfolded proteins in the endoplasmic reticulum (ER) or other ER-related stress; results in changes in the regulation of transcription and translation.


skeletal muscle tissue regeneration

description: The regrowth of skeletal muscle tissue to repair injured or damaged muscle fibers in the postnatal stage.


cardiac right ventricle morphogenesis

description: The process in which the right cardiac ventricle is generated and organized.


lysosome organization

description: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lysosome. A lysosome is a cytoplasmic, membrane-bounded organelle that is found in most animal cells and that contains a variety of hydrolases.


mRNA transcription

description: The cellular synthesis of messenger RNA (mRNA) from a DNA template.


name: positive regulation of myoblast differentiation

description: Any process that activates or increases the frequency, rate or extent of myoblast differentiation. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.


toll-like receptor 4 signaling pathway

description: The series of molecular signals initiated by a ligand binding to toll-like receptor 4.


name: cell surface receptor signaling pathway via JAK-STAT

description: A cell surface receptor signaling pathway in which ligand binding causes the receptor to dimerize, bringing the receptor-associated JAKs into close proximity. The JAKs then phosphorylate and activate each other on tyrosine residues.This leads to the activation of associated STAT protein, causing the STATs to dissociate from the receptor, translocate to the nucleus. The pathway ends with regulation of target gene expression by STAT proteins.


description: The series of molecular signals initiated by interleukin-6 binding to a receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.


T-helper 17 cell lineage commitment

description: The process in which a CD4-positive, alpha-beta T cell becomes committed to becoming a T-helper 17 cell, a CD4-positive, alpha-beta T cell with the phenotype RORgamma-t-positive that produces IL-17.


name: intrinsic apoptotic signaling pathway by p53 class mediator

description: The series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, and ends when the execution phase of apoptosis is triggered.


G2/M transition of mitotic cell cycle

description: The mitotic cell cycle transition by which a cell in G2 commits to M phase. The process begins when the kinase activity of M cyclin/CDK complex reaches a threshold high enough for the cell cycle to proceed. This is accomplished by activating a positive feedback loop that results in the accumulation of unphosphorylated and active M cyclin/CDK complex.


energy homeostasis

description: Any process involved in the balance between food intake (energy input) and energy expenditure.


name: regulation of cellular response to stress

description: Any process that modulates the frequency, rate or extent of a cellular response to stress. Cellular response to stress is a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).


maltose catabolic process

description: The chemical reactions and pathways resulting in the breakdown of the disaccharide maltose (4-O-alpha-D-glucopyranosyl-D-glucopyranose).


name: negative regulation of inflammatory response

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the inflammatory response.


cellular response to sulfur dioxide

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sulfur dioxide (SO2) stimulus.


positive regulation of gluconeogenesis

description: Any process that activates or increases the frequency, rate or extent of gluconeogenesis.


description: The series of molecular signals initiated by interleukin-2 binding to its receptor on the surface of a cell, and ending with the regulation of a downstream cellular process, e.g. transcription.


name: positive regulation of cellular senescence

description: Any process that activates or increases the frequency, rate or extent of cellular senescence.


description: The series of molecular signals initiated by interleukin-4 binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.


description: The series of molecular signals initiated by interleukin-3 binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.


description: The series of molecular signals initiated by interleukin-5 binding to its receptor on the surface of a cell, and ending with the regulation of a downstream cellular process, e.g. transcription.


eosinophil differentiation

description: The process in which a relatively unspecialized myeloid precursor cell acquires the specializes features of an eosinophil.


cellular response to nutrient levels

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of nutrients.


description: The series of molecular signals initiated by the binding of interleukin-11 to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.


T-helper 1 cell differentiation

description: The process in which a relatively unspecialized T cell acquires the specialized features of a T-helper 1 (Th1) cell. A Th1 cell is a CD4-positive, alpha-beta T cell that has the phenotype T-bet-positive and produces interferon-gamma.


description: The series of molecular signals initiated by interleukin-10 binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.


description: The series of molecular signals initiated by interleukin-15 binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.


name: type I interferon-mediated signaling pathway

description: The series of molecular signals initiated by type I interferon binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.


description: The series of molecular signals initiated by interleukin-9 binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.


regulatory T cell differentiation

description: The process in which a relatively unspecialized T cell acquires specialized features of a regulatory T cell. Regulatory T cells control or suppress immune responses through a variety of mechanisms and subsets include the CD4+CD25+ cell type as well as certain CD8+ cell types.


release from viral latency

description: The process by which a virus begins to replicate following a latency replication decision (switch).


name: signal transduction by p53 class mediator

description: An intracellular signaling process that is induced by the cell cycle regulator phosphoprotein p53 or an equivalent protein.


integrated stress response signaling

description: The series of molecular signals generated in response to diverse stress stimuli required to restore cellular homeostasis. The core event in this pathway is the phosphorylation of eIF2 alpha by one of four members of the eIF2a kinase family (EIF2AK1/HRI, EIF2AK2/PKR, EIF2AK3/PERK and EIF2AK4/GCN2), which leads to a decrease in global protein synthesis and the induction of selected genes, including the transcription factor ATF4, that together promote cellular recovery.


name: cellular response to phosphate starvation

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of phosphate.


name: cis-regulatory region sequence-specific DNA binding

description: Binding to a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site, located in cis relative to the transcription start site (i.e., on the same strand of DNA) of a gene transcribed by some RNA polymerase. Cis-regulatory sites are often referred to as a sequence motifs, enhancers, or silencers.


MAP kinase kinase activity

description: Catalysis of the concomitant phosphorylation of threonine (T) and tyrosine (Y) residues in a T-X-Y motif in the activation loop of a MAP kinase (MAPK) substrate.


MAP kinase activity

description: Catalysis of the reaction: protein + ATP = protein phosphate + ADP. This reaction is the phosphorylation of proteins. Mitogen-activated protein kinase; a family of protein kinases that perform a crucial step in relaying signals from the plasma membrane to the nucleus. They are activated by a wide range of proliferation- or differentiation-inducing signals; activation is strong with agonists such as polypeptide growth factors and tumor-promoting phorbol esters, but weak (in most cell backgrounds) by stress stimuli.


phosphatase activity

description: Catalysis of the hydrolysis of a phosphoric monoester, releasing a phosphate.


protein kinase inhibitor activity

description: Binds to and stops, prevents or reduces the activity of a protein kinase.


beta-catenin binding

description: Binding to a catenin beta subunit.


name: proteasome-mediated ubiquitin-dependent protein catabolic process

description: The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.


sequence-specific mRNA binding

description: Binding to messenger RNA (mRNA) of a specific nucleotide composition or a specific sequence motif.


name: transmembrane signaling receptor activity

description: Combining with an extracellular or intracellular signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity or state as part of signal transduction.


ISG15-specific peptidase activity

description: A thiol-dependent isopeptidase activity that cleaves ISG15 from a target protein to which it is conjugated.


name: protein tyrosine kinase activator activity

description: Increases the activity of a protein tyrosine kinase, an enzyme which phosphorylates a tyrosyl phenolic group on a protein.


cytokine receptor activity

description: Combining with a cytokine and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


kinase inhibitor activity

description: Binds to and stops, prevents or reduces the activity of a kinase.


growth factor activity

description: The function that stimulates a cell to grow or proliferate. Most growth factors have other actions besides the induction of cell growth or proliferation.


name: protein serine/threonine kinase activator activity

description: Binds to and increases the activity of a protein serine/threonine kinase.


GDP binding

description: Binding to GDP, guanosine 5'-diphosphate.


interleukin-2 receptor activity

description: Combining with interleukin-2 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


interleukin-4 receptor activity

description: Combining with interleukin-4 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


interleukin-3 receptor activity

description: Combining with interleukin-3 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


interleukin-5 receptor activity

description: Combining with interleukin-5 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


name: K63-linked polyubiquitin modification-dependent protein binding

description: Binding to a protein upon poly-ubiquitination formed by linkages between lysine residues at position 63 in the target protein.


interleukin-11 receptor activity

description: Combining with interleukin-11 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


interleukin-10 receptor activity

description: Combining with interleukin-10 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


interleukin-15 receptor activity

description: Combining with interleukin-15 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


phosphoserine residue binding

description: Binding to a phosphorylated serine residue within a protein.


interleukin-9 receptor activity

description: Combining with interleukin-9 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


calmodulin binding

description: Binding to calmodulin, a calcium-binding protein with many roles, both in the calcium-bound and calcium-free states.


type II interferon receptor activity

description: Combining with interferon-gamma (a type II interferon) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


deubiquitinase activator activity

description: Binds to and increases the activity of a deubiquitinase.


name: calmodulin-dependent protein phosphatase activity

description: Catalysis of the reaction: protein serine/threonine phosphate + H2O = protein serine/threonine + phosphate, dependent on the presence of calcium-bound calmodulin.


ligand-gated calcium channel activity

description: Enables the transmembrane transfer of a calcium ions by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts.


description: Catalysis of the reaction: S-adenosyl-L-methionine + (protein)-arginine = S-adenosyl-L-homocysteine + (protein)-N-methyl-arginine.


name: transforming growth factor beta receptor activity, type I

description: Combining with a complex of transforming growth factor beta and a type II TGF-beta receptor to initiate a change in cell activity; upon binding, acts as a downstream transducer of TGF-beta signals.


name: transforming growth factor beta receptor activity

description: Combining with a transforming growth factor beta (TGFbeta) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.


AMP-activated protein kinase activity

description: Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. This reaction requires the presence of AMP.


acetylation-dependent protein binding

description: Binding to a protein upon acetylation of the target protein.


protein-lysine 6-oxidase activity

description: Catalysis of the reaction: peptidyl-L-lysyl-peptide + H2O + O2 = peptidyl-allysyl-peptide + NH3 + hydrogen peroxide.


name: positive regulation of DNA-binding transcription factor activity

description: Any process that activates or increases the frequency, rate or extent of activity of a transcription factor, any factor involved in the initiation or regulation of transcription.


apoptotic process

description: A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died.


innate vocalization behavior

description: A vocalisation behavior that is innate, i.e. that does not need to be learned in order to occur.


regulation of action potential

description: Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination. This typically occurs via modulation of the activity or expression of voltage-gated ion channels.


hormone activity

description: The action characteristic of a hormone, any substance formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells in the same organism, upon which it has a specific regulatory action. The term was originally applied to agents with a stimulatory physiological action in vertebrate animals (as opposed to a chalone, which has a depressant action). Usage is now extended to regulatory compounds in lower animals and plants, and to synthetic substances having comparable effects; all bind receptors and trigger some biological process.


calcium ion transport

description: The directed movement of calcium (Ca) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


thymus development

description: The process whose specific outcome is the progression of the thymus over time, from its formation to the mature structure. The thymus is a symmetric bi-lobed organ involved primarily in the differentiation of immature to mature T cells, with unique vascular, nervous, epithelial, and lymphoid cell components.


parathyroid gland development

description: The process whose specific outcome is the progression of the parathyroid gland over time, from its formation to the mature structure. The parathyroid gland is an organ specialised for secretion of parathyroid hormone.


bone mineralization

description: The deposition of hydroxyapatite, a form of calcium phosphate with the formula Ca10(PO4)6(OH)2, in bone tissue.


translation

description: The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome.


integrin binding

description: Binding to an integrin.


name: retinoic acid receptor signaling pathway

description: A nuclear receptor-mediated signaling pathway initiated by a retinoic acid binding to an intracellular receptor of the nuclear receptor protein family, and ending with regulation of a downstream cellular process, e.g. transcription.


hematopoietic stem cell proliferation

description: The expansion of a hematopoietic stem cell population by cell division. A hematopoietic stem cell is a stem cell from which all cells of the lymphoid and myeloid lineages develop.


ERAD pathway

description: The protein catabolic pathway which targets endoplasmic reticulum (ER)-resident proteins for degradation by the cytoplasmic proteasome. It begins with recognition of the ER-resident protein, includes retrotranslocation (dislocation) of the protein from the ER to the cytosol, protein modifications necessary for correct substrate transfer (e.g. ubiquitination), transport of the protein to the proteasome, and ends with degradation of the protein by the cytoplasmic proteasome.


intrinsic apoptotic signaling pathway

description: The series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway starts with reception of an intracellular signal (e.g. DNA damage, endoplasmic reticulum stress, oxidative stress etc.), and ends when the execution phase of apoptosis is triggered. The intrinsic apoptotic signaling pathway is crucially regulated by permeabilization of the mitochondrial outer membrane (MOMP).


protein-containing complex binding

description: Binding to a macromolecular complex.


translation repressor activity

description: Antagonizes ribosome-mediated translation of mRNA into a polypeptide.


alkaline phosphatase activity

description: Catalysis of the reaction: a phosphate monoester + H2O = an alcohol + phosphate, with an alkaline pH optimum.


structural constituent of bone

description: The action of a molecule that contributes to the structural integrity of bone.


retinoic acid 4-hydroxylase activity

description: Catalysis of the conversion of retinoic acid to 4-hydroxy-retinoic acid.


name: transmembrane receptor protein tyrosine kinase activity

description: Combining with a signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP + a protein-L-tyrosine = ADP + a protein-L-tyrosine phosphate.


oxygen carrier activity

description: Binding to oxygen and delivering it to an acceptor molecule or a specific location.


name: glial cell-derived neurotrophic factor receptor activity

description: Combining with glial cell line-derived neurotrophic factor and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


inner cell mass derived epiblast

description: An embryonic structure that is derived from the inner cell mass and lies above the hypoblast and gives rise to the three primary germ layers.


erythroid lineage cell

category: biolink:Cell biolink:AnatomicalEntity biolink:PhysicalEssence biolink:OrganismalEntity biolink:SubjectOfInvestigation biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: A immature or mature cell in the lineage leading to and including erythrocytes.


eosinophil

description: Any of the immature or mature forms of a granular leukocyte with a nucleus that usually has two lobes connected by one or more slender threads of chromatin, and cytoplasm containing coarse, round granules that are uniform in size and which can be stained by the dye eosin. Eosinophils are CD9-positive, CD191-positive, and CD193-positive.


name: CCL2_HUMAN C-C motif chemokine 2 (sprot)

description: A C-C motif chemokine 2 that is encoded in the genome of human.


name: SOCS3_HUMAN Suppressor of cytokine signaling 3 (sprot)

description: A suppressor of cytokine signaling 3 that is encoded in the genome of human.


name: CHD4_HUMAN Chromodomain-helicase-DNA-binding protein 4 (sprot)

description: A chromodomain-helicase-DNA-binding protein 4 that is encoded in the genome of human.


name: I10R1_HUMAN Interleukin-10 receptor subunit alpha (sprot)

description: An interleukin-10 receptor subunit alpha that is encoded in the genome of human.


IFNB_HUMAN Interferon beta (sprot)

An interferon beta 1 that is encoded in the genome of human.


name: CXL10_HUMAN C-X-C motif chemokine 10 (sprot)

description: A C-X-C motif chemokine 10 that is encoded in the genome of human.


TLR3_HUMAN Toll-like receptor 3 (sprot)

A Toll-like receptor 3 that is encoded in the genome of human.


name: BZLF1_EBVB9 Lytic switch protein BZLF1 (sprot)

description: A protein that is a translation product of the BZLF1 gene in Human herpesvirus 4 strain B95-8.


name: GDF15_HUMAN Growth/differentiation factor 15 (sprot)

description: A growth/differentiation factor 15 that is encoded in the genome of human.


anatomical structure morphogenesis

description: The process in which anatomical structures are generated and organized. Morphogenesis pertains to the creation of form.


endoderm development

description: The process whose specific outcome is the progression of the endoderm over time, from its formation to the mature structure. The endoderm is the innermost germ layer that develops into the gastrointestinal tract, the lungs and associated tissues.


digestive tract development

description: The process whose specific outcome is the progression of the digestive tract over time, from its formation to the mature structure. The digestive tract is the anatomical structure through which food passes and is processed.


dorsal/ventral axis specification

description: The establishment, maintenance and elaboration of the dorsal/ventral axis. The dorsal/ventral axis is defined by a line that runs orthogonal to both the anterior/posterior and left/right axes. The dorsal end is defined by the upper or back side of an organism. The ventral end is defined by the lower or front side of an organism.


ectoderm development

description: The process whose specific outcome is the progression of the ectoderm over time, from its formation to the mature structure. In animal embryos, the ectoderm is the outer germ layer of the embryo, formed during gastrulation.