A sphingoid 1-phosphate that is hexadecasphing-4-enine substituted by a phospho group at position 1.


A methyl ketone heptan-2-one carrying a double bond at position 4.


name: Malignant neoplasm of skin of other and unspecified parts of face

category: biolink:Disease biolink:DiseaseOrPhenotypicFeature biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing

description: Evidence of other malignant neoplasm of skin of unspecified parts of face not specified elsewhere.


name: Orbital Sarcoma Pathologic Regional Lymph Nodes TNM Finding v8

category: biolink:PhenotypicFeature biolink:DiseaseOrPhenotypicFeature biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing

description: A pathologic finding about one or more characteristics of orbital sarcoma, following the rules of the TNM AJCC v8 classification system as they pertain to staging of regional lymph nodes.


name: Orbital Sarcoma Pathologic TNM Finding v8

description: A pathologic finding about one or more characteristics of orbital sarcoma, following the rules of the TNM AJCC v8 classification system.


Orbital Sarcoma pN0 TNM Finding v8

description: Orbital sarcoma with no regional lymph node metastasis. (from AJCC 8th Ed.)


Orbital Sarcoma pT2 TNM Finding v8

description: Orbital sarcoma with tumor measuring more than 2 cm in greatest diameter without invasion of bony walls or globe. (from AJCC 8th Ed.)


Orbital Sarcoma pTX TNM Finding v8

description: Primary tumor cannot be assessed. (from AJCC 8th Ed.)


Orbital Sarcoma pT1 TNM Finding v8

description: Orbital sarcoma with tumor measuring 2 cm or less in greatest dimension. (from AJCC 8th Ed.)


Orbital Sarcoma pNX TNM Finding v8

description: Orbital sarcoma in which the regional lymph nodes cannot be assessed. (from AJCC 8th Ed.)


Orbital Sarcoma pT3 TNM Finding v8

description: Orbital sarcoma with tumor of any size with invasion of bony walls. (from AJCC 8th Ed.)


Orbital Sarcoma pT0 TNM Finding v8

description: No evidence of primary tumor. (from AJCC 8th Ed.)


Orbital Sarcoma pN1 TNM Finding v8

description: Orbital sarcoma with regional lymph node metastasis. (from AJCC 8th Ed.)


name: Orbital Sarcoma Pathologic Primary Tumor TNM Finding v8

description: A pathologic finding about one or more characteristics of orbital sarcoma, following the rules of the TNM AJCC v8 classification system as they pertain to staging of the primary tumor.


Orbital Sarcoma pM1 TNM Finding v8

description: Orbital sarcoma with distant metastasis. (from AJCC 8th Ed.)


name: Orbital Sarcoma Pathologic Distant Metastasis TNM Finding v8

description: A pathologic finding about one or more characteristics of orbital sarcoma, following the rules of the TNM AJCC v8 classification system as they pertain to distant metastases.


A 3-(difluoromethyl)-N-(9-isopropyl-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl)-1-methylpyrazole-4-carboxamide that is the syn-(1S,4R,9S)-diastereomer of isopyrazam.


Human Papillomavirus Negative

description: Indicates that human papillomavirus has not been detected in a sample.


Human Papillomavirus-16 Negative

description: An indication that human papillomavirus-16 has not been detected in a sample.


name: Papillary, Follicular, Hurthle Cell, Poorly Differentiated, and Anaplastic Thyroid Carcinoma pT1b TNM Finding v8

description: Tumor measuring more than 1 cm but 2 cm or less in greatest dimension limited to the thyroid. (from AJCC 8th Ed.)


raltegravir

A pyrimidone that is pyrimidin-4(3H)-one in which the hydrogens at positions 2, 3, 5 and 6 are replaced by 2-[(5-methyl-1,3,4-oxadiazole-2-carbonyl)amino]propan-2-yl, methyl, hydroxy, and N-[(4-fluorophenyl)methyl]aminoacyl groups, respectively. It is an antiretroviral drug used for treatment of HIV infection.


Elevated Catecholamine Metabolites

description: A finding indicating elevated concentrations of catecholamine metabolites in a biological sample.


Grade 4 Bronchospasm, CTCAE

description: Life-threatening respiratory or hemodynamic compromise; intubation or urgent intervention indicated


Grade 2 Lymphedema, CTCAE

description: Marked discoloration; leathery skin texture; papillary formation; limiting instrumental ADL


name: Grade 1 Cranial Nerve I Intra-Operative Injury, CTCAE


name: Unspecified Malignant Neoplasm Skin of Right Upper Limb, Including Shoulder

description: Evidence of unspecified malignant neoplasm skin of the right upper limb including the shoulder.


alcohol abuse with withdrawal delirium

description: Evidence of alcohol abuse with withdrawal delirium.


name: Grade 4 Bone Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


Grade 2 Soft Tissue Infection, CTCAE

description: Localized; oral intervention indicated (e.g., antibiotic, antifungal, or antiviral)


name: Atherosclerosis of Unspecified Type of Bypass Graft(s) of the Extremities with Rest Pain, Other Extremity

description: Evidence of atherosclerosis of unspecified type of bypass graft(s) of the extremities with rest pain in the other extremity.


Breast Cancer pT1b TNM Finding v8

description: Breast cancer with tumor size more than 5 mm, but not more than 10 mm in greatest dimension. (from AJCC 8th Ed.)


name: Gallbladder Intracholecystic Papillary Neoplasm, High Grade

description: An intracholecystic papillary neoplasm that arises from the epithelium of the gallbladder. It is characterized by the presence of severe epithelial atypia.


Wheezing, CTCAE

description: A disorder characterized by a high-pitched, whistling sound during breathing. It results from the narrowing or obstruction of the respiratory airways.


Gestational diabetes mellitus class A1

description: Carbohydrate intolerance first diagnosed during pregnancy. Diagnosis from abnormal oral glucose tolerance test (OGTT) but normal glucose levels when fasting and two hours post-prandial. Euglycemia achieved with diet and/or exercise.


name: Carcinoma of the Conjunctiva cM1 TNM Finding v7

description: Carcinoma of the conjunctiva with distant metastasis. (from AJCC 7th Ed.)


name: Grade 2 Upper Airway Infection NOS with Unknown Absolute Neutrophil Count, CTCAE


name: Colon or Rectum Neuroendocrine Tumor pT2 TNM Finding v7

description: Colon or rectum neuroendocrine tumor invading muscularis propria or is more than 2 cm in size with invasion of lamina propria or submucosa. (from AJCC 7th Ed.)


Grade 4 Biliary Tract Infection, CTCAE

description: Life-threatening consequences; urgent intervention indicated


name: Congenital malformation of aortic and mitral valves, unspecified

description: Evidence of congenital malformation of aortic and mitral valves.


Carcinomatosis of peritoneal cavity

description: A condition in which a carcinoma has spread extensively throughout the peritoneum.


name: Childhood Acute Myeloid Leukemia with Maturation

description: An acute myeloid leukemia with maturation occurring in children.


name: Grade 3 Duodenum Intra-Operative Injury, CTCAE


name: Grade 1 Right Ventricular Dysfunction, CTCAE

description: Asymptomatic with laboratory (e.g., BNP [B-Natriuretic Peptide ]) or cardiac imaging abnormalities


name: Merkel Cell Carcinoma pN1a(sn) TNM Finding v8

description: Merkel cell carcinoma with clinically occult regional lymph node metastasis identified only by sentinel lymph node biopsy. (from AJCC 8th Ed.)


name: Bipolar Disorder, Current Episode Manic without Psychotic Features, Moderate

description: Evidence of bipolar disorder that is current episode manic without psychotic features that is moderate.


Type B Lymphomatoid Papulosis

description: A variant of lymphomatoid papulosis characterized by an epidermotropic infiltrate composed of small atypical cerebriform-like lymphocytes.


name: Grade 2 Social Circumstances - Other, Specify, CTCAE

description: Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL


name: Diffuse Pediatric-Type High Grade Glioma MYCN

description: An aggressive, WHO grade 4 diffuse glioma usually affecting children, adolescents, or young adults. It is characterized by the expression of MYCN molecular signature.


Urethral Infection, CTCAE

description: A disorder characterized by an infectious process involving the urethra.


Welding Exposure

description: Environmental, occupational, or consumer-based exposure to vaporized materials or dusts created during the welding process.


name: Merkel Cell Carcinoma Pathologic Distant Metastasis TNM Finding v7

description: A pathologic finding about one or more characteristics of Merkel cell carcinoma, following the rules of the TNM AJCC v7 classification system as they pertain to distant metastases. (from AJCC 7th Ed.)


Retropharyngeal Abscess

description: An abscess that develops in the soft tissues behind the posterior pharyngeal wall.


Jaccoud Arthropathy, Left Elbow

description: Evidence of Jaccoud arthropathy in the left elbow.


Factor IX Inactivation

description: Presence of inactivating antibodies to factor IX in the blood.


name: Enteropathic Arthropathies, Right Shoulder

description: Evidence of enteropathic arthropathies in the right shoulder.


name: Mycosis Fungoides and Sezary Syndrome M0 TNM Finding v7

description: No visceral organ involvement. (from AJCC 7th Ed.)


Benign neoplasm of adnexa of skin

description: A neoplasm that arises from the hair follicles, sebaceous glands, or sweat glands. It is characterized by the absence of atypical or malignant cytological and architectural features, and absence of invasive features or metastatic potential. Representative examples include cylindroma, hidrocystoma, hidradenoma, and sebaceoma.


Grade 1 Sore Throat, CTCAE

description: Mild pain


Environmental Exposure

description: Exposure to potentially harmful chemical, physical, or biological agents via the environment.


name: Ocular Adnexal Lymphoma cM1c TNM Finding v7

description: Both M1a and M1b involvement. (from AJCC 7th Ed.)


Emotional Distress

description: Disturbed mental state characterized by moodiness, irritability, agitation, anxiety, and/or depression resulting from physical or mental stress.


Post-COVID-19 Symptom

description: A symptom reported following recovery from COVID-19.


Testicular Cancer cNX TNM Finding v7

description: Testicular cancer in which the regional lymph nodes cannot be assessed.  (from AJCC 7th Ed.)


description: Evidence of cocaine abuse with cocaine-induced psychotic disorder with hallucinations.


Adult Grade I Meningioma

description: A grade I meningioma that occurs during adulthood.


name: Recurrent Lymphocyte-Rich Classic Hodgkin Lymphoma

description: The reemergence of lymphocyte-rich classic Hodgkin lymphoma after a period of remission.


Penile Cancer cN1 TNM Finding v8

description: Penile cancer with palpable mobile unilateral inguinal lymph node. (from AJCC 8th Ed.)


Grade 4 Hypoxia, CTCAE

description: Life-threatening airway compromise; urgent intervention indicated (e.g., tracheotomy or intubation)


Decreased Expression

description: An indication that the expression of a gene, transcript or protein is lower than a previous value or a normal range of values.


Torturing Pain

description: A sensation of having discomfort or distress inflicted upon an individual.


name: High Grade Appendix Mucinous Adenocarcinoma

description: A mucinous adenocarcinoma that arises from the appendix. The malignant cells are numerous and exhibit high grade dysplasia.  It may be associated with pseudomyxoma peritonei, but unlike the low grade mucinous neoplasm, it invades other organs and metastasizes to distant anatomic sites.


Needle track

description: Visible marks on the skin caused by puncture wounds, most commonly associated with intravenous drug use.


name: Nasopharyngeal Cancer pT3 TNM Finding v7

description: Nasopharyngeal cancer with tumor involving bony structures of skull base and/or paranasal sinuses. (from AJCC 7th Ed.)


Recurrent Malignant Abdominal Neoplasm

description: The reemergence of a malignant abdominal neoplasm after a period of remission.


name: Larynx Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


Grade 3 Vasculitis, CTCAE

description: Severe symptoms, medical intervention indicated (e.g., steroids)


name: Major Salivary Gland Cancer Pathologic Distant Metastasis TNM Finding v8

description: A pathologic finding about one or more characteristics of major salivary gland cancer, following the rules of the TNM AJCC v8 classification system as they pertain to distant metastases.


Neuralgia, CTCAE

description: A disorder characterized by intense painful sensation along a nerve or group of nerves.


Gallbladder Necrosis, CTCAE 5.0

description: A disorder characterized by a necrotic process occurring in the gallbladder.


name: Right Posterior Middle Transition Zone of Prostate

description: The region of the prostate that is located on the anatomical right side of the posterior portion of the middle division of the transition zone.


Grade 4 Mitral Valve Disease, CTCAE

description: Life-threatening consequences; urgent intervention indicated (e.g., valve replacement, valvuloplasty)


name: Grade 4 Radiation Excluding Chemoradiation, CTCAE


name: Conjunctival Melanoma Pathologic Regional Lymph Nodes TNM Finding v8

description: A pathologic finding about one or more characteristics of conjunctival melanoma, following the rules of the TNM AJCC v8 classification system as they pertain to staging of regional lymph nodes.


Adult Classical Hodgkin Lymphoma

description: Classic Hodgkin lymphoma that occurs in adults.


name: Drug or Chemical Induced Diabetes Mellitus with Stable Proliferative Diabetic Retinopathy, Right Eye

description: Evidence of drug or chemical induced diabetes mellitus with stable proliferative diabetic retinopathy in the right eye.


name: Nasal Cavity and Paranasal Sinuses Cancer Pathologic Regional Lymph Nodes TNM Finding v8

description: A pathologic finding about one or more characteristics of nasal cavity and paranasal sinuses cancer, following the rules of the TNM AJCC v8 classification system as they pertain to staging of regional lymph nodes.


name: Childhood Acute Lymphoblastic Leukemia CNS 1 Toronto Guidelines v2

description: No clinical signs of CNS involvement and no blasts in CSF. (Childhood cancer staging for population registries according to the Toronto Childhood Cancer Stage Guidelines - Version 2. Cancer Council Queensland and Cancer Australia: Brisbane, Australia; 2021.)


Biomechanical lesion, unspecified

description: A localized defect of soft tissue or bone that results in the altered function of an associated anatomic structure.


Elevated LIF

description: A finding indicating elevated concentrations of LIF in a sample.


Adenomatous hyperplasia

description: Proliferation of the glandular epithelial cells.


name: Appendiceal Carcinoid Clinical TNM Finding v7

description: A clinical finding about one or more characteristics of appendiceal carcinoid, following the rules of the TNM AJCC v7 classification system.  Clinical assessment is based on medical history, physical examination, and imaging.  Determination of elevated urinary 5-HIAA may indicate liver metastasis. (from AJCC 7th Ed.)


Stage IIB Appendix Carcinoma AJCC v8

description: Stage IIB includes: T4a, N0, M0. T4a: Tumor invades through the visceral peritoneum, including the acellular mucin or mucinous epithelium involving the serosa of the appendix or serosa of the mesoappendix. N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 8th ed.)


Lung Cancer pM1 TNM Finding v6

description: Lung cancer with distant metastasis. (from AJCC 6th Ed.)


Burning Waste Smoke Exposure

description: Environmental or occupational exposure to airborne gases and particulates produced when trash or waste is burned.


Grade 2 Renal Hemorrhage, CTCAE

description: Analgesics and hematocrit monitoring indicated


Posterior Subcapsular Cataract Grade 4

description: A stage of posterior subcapsular cataract characterized by greater than 50% of the posterior capsule obscured by opacity. (Modified LOCS II)


Grade 4 Gastrointestinal Fistula, CTCAE

description: Life-threatening consequences; urgent intervention indicated


name: Stage IIA Gestational Trophoblastic Tumor AJCC v7

description: Stage IIA includes: T2, M0, Risk factors: low risk.  T2: Tumor extends to other genital structures (ovary, tube, vagina, broad ligaments) by metastasis or direct extension.  M0: No distant metastasis.  (AJCC 7th ed.)


Substance Adverse Event

description: An unexpected or dangerous reaction to a substance (e.g., food, environmental agent). (ACC)


Normal Coronary Arteriogram

description: An x-ray of the coronary arteries that reveals normal results.


Grade 2 Rectal Pain, CTCAE

description: Moderate pain; limiting instrumental ADL


Grade 2 Capillary Leak Syndrome, CTCAE

description: Symptomatic; medical intervention indicated


Colonic Obstruction, CTCAE

description: A disorder characterized by blockage of the normal flow of the intestinal contents in the colon.


name: Rheumatic Disorders of Both Aortic and Tricuspid Valves

description: Evidence of rheumatic disorders of both aortic and tricuspid valves.


Grade 2 Arachnoiditis, CTCAE

description: Moderate symptoms; limiting instrumental ADL


name: Retroperitoneum injury with open wound into cavity

description: Trauma to  retroperitoneal tissue associated with a wound that extends into the retroperitoneal space.


Adult Giant Cell Glioblastoma

description: A giant cell glioblastoma occurring in adults.


Osteosclerotic Lesion

description: A bone lesion that is associated with unusual thickening of the bone.


name: Oral Cavity NOS Intra-Operative Injury, CTCAE


name: Grade 3 Intraoperative Musculoskeletal Injury, CTCAE

description: Complete resection or reconstruction of injured organ/structure indicated; limiting self care ADL


Moderate Cardiac Valve Regurgitation

description: Evidence of moderate retrograde blood flow through the valve(s) of the heart. (ACC)


AV Fistula Maturation Failure

description: Inadequate development of an arteriovenous fistula within three months of creation.


name: Juvenile Arthritis, Unspecified, Right Hip

description: Evidence of unspecified juvenile arthritis in the right hip.


name: Grade 4 Brain Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


name: Grade 2 Injection Site Reaction or Extravasation Changes, CTCAE


name: Cerebral Infarction due to Unspecified Occlusion or Stenosis of Left Post Cerebral Artery

description: Evidence of cerebral infarction due to an unspecified occlusion or stenosis of the left post cerebral artery.


Testicular Cancer cT4 TNM Finding v8

description: Testicular cancer in which the tumor invades scrotum with or without vascular/lymphatic invasion. (from AJCC 8th Ed.)


Myelodysplastic Syndrome, CTCAE

description: A disorder characterized by insufficiently healthy hematapoietic cell production by the bone marrow.


name: Enteropathic Arthropathies, Left Shoulder

description: Evidence of enteropathic arthropathies in the left shoulder.


name: Grade 4 Bladder Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


Recurrent Anal Adenocarcinoma

description: The reemergence of anal adenocarcinoma after a period of remission.


Recurrent tumor

description: The reemergence of a neoplasm after a period of remission.


Grade 2 Laryngeal Inflammation, CTCAE

description: Moderate sore throat; analgesics indicated


Drug Induced Thrombocytopenia

description: Thrombocytopenia caused by ingested or injected drugs. It may be the result of decreased platelet production due to bone marrow suppression or increased rate of platelet destruction.


Metastatic malignant neoplasm to vagina

description: A malignant neoplasm that has spread to the vagina from another anatomic site.


name: pre-existing hypertensive chronic kidney disease complicating puerperium

description: Evidence of pre-existing hypertensive chronic kidney disease complicating the puerperium.


name: Parathyroid Carcinoma pN1b TNM Finding v8

description: Metastasis to unilateral, bilateral, or contralateral cervical (levels I, II, III, IV, or V) or retropharyngeal nodes. (from AJCC 8th Ed.)


Beam Hardening Artifact

description: An artifact resulting from absorpsion of lower energy photons as the beam penetrates through a tissue.


name: Other Disorders of Brain in Diseases Classified Elsewhere

description: Evidence of other disorders of brain in diseases classified elsewhere not specified elsewhere.


name: Lip and Oral Cavity Cancer pMX TNM Finding v6

description: Lip and oral cavity cancer in which distant metastasis cannot be assessed. (from AJCC 6th Ed.)


name: Colorectal Cancer Pathologic Regional Lymph Nodes TNM Finding v8

description: A pathologic finding about one or more characteristics of colorectal cancer, following the rules of the TNM AJCC v8 classification system as they pertain to staging of regional lymph nodes.


name: Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries

description: Evidence of cerebral infarction due to an unspecified occlusion or stenosis of the cerebral artery.


Upper GI Complete Response GvHD

description: An NIH upper GI score of 0 after previous GvHD involvement.


name: Ampulla of Vater Cancer by AJCC v8 Stage

description: A term that refers to the staging of ampulla of Vater cancer according to the American Joint Committee on Cancer, 8th edition. This staging system does not apply to well-differentiated neuroendocrine (carcinoid) tumors but does apply to high-grade neuroendocrine carcinomas, such as small cell carcinoma and large cell neuroendocrine carcinoma. (from AJCC 8th Ed.)


Cervical Cancer pT2b TNM Finding v9

description: Cervical carcinoma with parametrial invasion but not up to the pelvic wall. (from AJCC 9th Ed.)


name: Grade 1 Peripheral Sensory Nerve NOS Intra-Operative Injury, CTCAE


Grade 1 Hepatic Pain, CTCAE

description: Mild pain


name: Arthropathy following Intestinal Bypass, Left Elbow

description: Evidence of arthropathy following intestinal bypass in the left elbow.


name: Biliary Tree NOS Intra-Operative Injury, CTCAE


name: Other Specified Rheumatoid Arthritis, Left Ankle and Foot

description: Evidence of other specified rheumatoid arthritis in the left ankle and foot not specified elsewhere.


name: Recurrent Malignant Spermatic Cord Neoplasm

description: The reemergence of a malignant spermatic cord neoplasm after a period of remission.


name: Ocular Adnexal Lymphoma pNX TNM Finding v8

description: Involvement of lymph nodes not assessed. (from AJCC 8th Ed.)


name: Retinoblastoma Clinical Distant Metastasis TNM Finding v7

description: A clinical finding about one or more characteristics of retinoblastoma, following the rules of the TNM AJCC v7 classification system as they pertain to distant metastases.


name: Grade 1 Urinary Frequency or Urgency, CTCAE


name: Malignant Non-Hodgkin's Lymphoma, Small Cleaved Cell


Grade 3 Eyelid Function Disorder, CTCAE

description: Limiting self care ADL; operative intervention indicated


Invasive Cutaneous Melanoma

description: A melanoma of the skin that is not confined to the dermal-epidermal junction, and has infiltrated the dermis.


name: Grade 3 Hypoglossal Nerve Disorder, CTCAE

description: Severe symptoms; limiting self care ADL


name: Other Psychoactive Substance Abuse, Uncomplicated

description: Evidence of other psychoactive substance abuse, uncomplicated not specified elsewhere.


name: Atherosclerosis of Non-Autologous Biological Bypass Graft(s) of the Extremities with Intermittent Claudication, Other Extremity

description: Evidence of atherosclerosis of non-autologous biological bypass graft(s) of the extremities with intermittent claudication in the other extremity.


name: Secondary Malignant Neoplasm of Unspecified Respiratory Organ

description: Evidence of secondary malignant neoplasm of unspecified respiratory organ.


name: Grade 2 Bronchus Infection with Unknown Absolute Neutrophil Count, CTCAE


name: Carcinoma in situ of skin of other sites

description: Evidence of carcinoma in situ of the skin of other sites.


name: Grade 4 Parotid Gland Intra-Operative Injury, CTCAE


name: Papillary, Follicular, Hurthle Cell, Poorly Differentiated, and Anaplastic Thyroid Carcinoma Pathologic Primary Tumor TNM Finding v8

description: A pathologic finding about one or more characteristics of papillary, follicular, Hurthle cell, poorly differentiated, and anaplastic thyroid carcinoma, following the rules of the TNM AJCC v8 classification system as they pertain to staging of the primary tumor.


Vulvar Cancer cM1 TNM Finding v8

description: Vulvar cancer with distant metastasis (including pelvic lymph node metastasis). (from AJCC 8th Ed.)


Non-Hematologic Toxicity

description: A toxicity that impairs or damages other than the hematologic system.


Mediastinal Diseases

description: A non-neoplastic or neoplastic disorder that affects the structures of the mediastinum.  Representative examples include mediastinitis, mediastinal lipoma, mediastinal schwannoma, thymoma, and mediastinal lymphoma.


name: FIGO Stage I Gestational Trophoblastic Tumor

description: Lesion is confined to the uterus.


name: Atherosclerosis of Autologous Vein Bypass Graft(s) of Right Leg with Ulceration of Unspecified Site

description: Evidence of atherosclerosis of autologous vein bypass graft(s) of right leg with ulceration of unspecified site.


Sweating fever

description: A febrile response accompanied by diaphoresis.


Anticipated Adverse Event

description: An adverse event that is reasonably expected and/or listed in the clinical protocol or other study-related document.


name: Other Stimulant Dependence with Other Stimulant-Induced Disorder

description: Evidence of other stimulant dependence with other stimulant-induced disorder not specified elsewhere.


name: Acute Peptic Ulcer, Site Unspecified, with both Hemorrhage and Perforation

description: Evidence of an acute peptic ulcer, site unspecified, with both hemorrhage and perforation.


Recurrent Gliomatosis Cerebri

description: The reemergence of gliomatosis cerebri after a period of remission.


name: Vaginal Cancer Pathologic Regional Lymph Nodes TNM Finding v8

description: A pathologic finding about one or more characteristics of vaginal cancer, following the rules of the TNM AJCC v8 classification system as they pertain to staging of regional lymph nodes.


name: HPV-Mediated (p16-Positive) Oropharyngeal Cancer pT1 TNM Finding v8

description: HPV-mediated (p16-positive) oropharyngeal cancer with tumor 2 cm or smaller in greatest dimension. (from AJCC 8th Ed.)


Lacrimal Gland Oncocytoma

description: A benign epithelial neoplasm that arises from the lacrimal gland. It is characterized by the presence of oncocytic cells with abundant eosinophilic and granular cytoplasm.


name: secondary carcinoid tumor of distant lymph nodes

description: Evidence of secondary carcinoid tumors of distant lymph nodes.


name: Grade 5 Middle Ear Infection with Unknown Absolute Neutrophil Count, CTCAE


Fallopian Tube Non-Neoplastic Disorder

description: A non-neoplastic disorder that affects the fallopian tube.  Representative examples include acute and chronic salpingitis, salpingitis isthmica nodosa, and endometriosis.


name: Grade 1 Laryngeal Nerve Dysfunction, CTCAE


name: Grade 5 Upper Airway Infection NOS Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


name: Embolism and thrombosis of unspecified artery

description: Evidence of embolism and thrombosis of unspecified artery.


Prosthetic valve endocarditis

description: Endocarditis occurring on parts of a valve prosthesis or a reconstructed heart valve; it can be classified into early and late prosthetic valve endocarditis.


name: non-Hodgkin's lymphoma of extranodal and solid organ sites

description: Evidence of non-Hodgkin lymphoma in the extranodal and solid organ sites.


name: Grade 1 Cranial Nerve X Neuropathy, CTCAE


Urethral Cancer TNM Finding v8

description: A finding about one or more characteristics of urethral cancer, following the rules of the TNM AJCC v8 classification system. This classification system applies to urothelial (transitional cell), squamous, and glandular carcinomas of the urethra and to urothelial (transitional cell) carcinomas of the prostate and prostatic urethra. It does not apply to squamous cell carcinomas of the penile foreskin (are staged according to the classification for penis), primary urothelial carcinomas of the bladder with transmural involvement of the prostate (are staged according to the classification for urinary bladder), prostatic adenocarcinomas (are staged according to the classification for prostate), mucosal melanomas of the urethra (no AJCC staging system), lymphomas (are staged according to the classification for Hodgkin and non-Hodgkin lymphoma), and sarcomas (are staged according to the classification for soft tissue sarcoma of the abdomen and thoracic visceral organs).  (from AJCC 8th Ed.)


name: Primary cutaneous CD4 positive small/medium T-cell lymphoproliferative disorder

description: A primary cutaneous T-cell lymphoproliferative disorder.  It usually presents with a solitary plaque or tumor on the face, neck, or upper trunk.  Morphologically, it is composed of small to medium-sized CD4-positive, CD8-negative, and CD30-negative pleomorphic T-lymphocytes.  A small number of large pleomorphic T-lymphocytes may also be present.  The lymphocytic infiltrate is dermal.  Focal epidermotropism and subcutaneous involvement may be present.  The clinical behavior is almost always indolent and most patients present with localized disease.


name: Infection by methicillin sensitive Staphylococcus aureus

description: A bacterial infection that is caused by Staphylococcus aureus that is susceptible to methicillin.


Refractory Leukemia

description: Leukemia that is resistant to treatment.


name: Grade 5 Pulmonary Fibrosis Radiographic Changes, CTCAE


name: Grade 4 Bronchospasm and Wheezing, CTCAE


name: Locally Advanced Unresectable Malignant Neoplasm

description: A malignant neoplasm that has spread from its original site of growth to nearby tissues or lymph nodes and is not amenable to surgical resection.


Childhood Diffuse Astrocytoma

description: A diffuse astrocytoma that occurs during childhood.


name: Conjunctival Carcinoma pT1 TNM Finding v8

description: Conjunctival carcinoma with tumor measuring 5 mm or less in greatest dimension and invading through the conjunctival basement membrane without invasion of adjacent structures. (from AJCC 8th Ed.)


Grade 5 Pharyngeal Mucositis, CTCAE

description: Death


name: Cerebral Infarction due to Thrombosis Unspecified Anterior Cerebral Artery

description: Evidence of cerebral infarction due to a thrombosis of an unspecified anterior cerebral artery.


name: Gestational Trophoblastic Neoplasm Pathologic Primary Tumor TNM Finding v8

description: A pathologic finding about one or more characteristics of a gestational trophoblastic neoplasm, following the rules of the TNM AJCC v8 classification system as they pertain to staging of the primary tumor.


Grade 3 Dyspareunia, CTCAE

description: Severe discomfort or pain associated with vaginal penetration; discomfort or pain unrelieved by vaginal lubricants or estrogen


name: Diabetes Mellitus due to Underlying Condition with Mild Non-Proliferative Diabetic Retinopathy with Macular Edema, Unspecified Eye

description: Evidence of diabetes mellitus due to underlying condition with mild non-proliferative diabetic retinopathy with macular edema in an unspecified eye.


Stage IIIC Vulvar Cancer AJCC v8

description: Stage IIIC includes: T1-T2, N2c, M0. T1: Tumor confined to the vulva and/or perineum. Multifocal lesions should be designated as such. The largest lesion or the lesion with the greatest depth of invasion will be the target lesion identified to address the highest pT stage. Depth of invasion is defined as the measurement of the tumor from the epithelial-stromal junction of the adjacent most superficial dermal papilla to the deepest point of invasion. T2: Tumor of any size with extension to adjacent perineal structures (lower/distal third of the urethra, lower/distal third of the vagina, anal involvement). N2c: Lymph node(s) metastasis with extranodal extension. M0: No distant metastasis. (AJCC 8th Ed.)


name: Low Grade Conjunctival Melanocytic Intraepithelial Lesion

description: Conjunctival melanocytic intraepithelial lesion characterized by the presence of mild atypia.


Skin Pain

description: Painful sensation in the skin.


name: MUSCULAR DYSTROPHY, LIMB-GIRDLE, TYPE 1C

description: A sub-type of limb-girdle muscular dystrophy caused by mutation(s) in the CAV3 gene, encoding caveolin-3.


name: Grade 1 Colon or Cecum or Appendix Fistula, CTCAE


name: Atherosclerosis of Non-Autologous Biological Bypass Graft(s) of Right Leg with Ulceration of Heel and Midfoot

description: Evidence of atherosclerosis of non-autologous biological bypass graft(s) of right leg with ulceration of heel and midfoot.


name: Exocrine Pancreatic Cancer pN1b TNM Finding

description: Exocrine pancreatic cancer with metastasis to more than one regional lymph node. (from CAP Cancer of the Endocrine Pancreas Protocol- January 2005 Revision)


name: Nasal Cavity and Ethmoid Sinus Cancer pT1 TNM Finding v6 and v7

description: Nasal cavity and ethmoid sinus cancer with tumor restricted to any one subsite, with or without bony invasion. (from AJCC 6th and 7th Eds.)


name: Intraoperative Gastrointestinal Injury, CTCAE

description: A finding of damage to the gastrointestinal system during a surgical procedure.


Lymphocyte Count Decreased, CTCAE

description: A finding based on laboratory test results that indicate a decrease in number of lymphocytes in a blood specimen.


name: congenital malformation syndromes due to known exogenous causes

description: A syndrome characterized by the presence of structural malformations that are present at birth and can be attributed to an exogenous cause.


Nagging Pain

description: A sensation of discomfort or distress that is persistent and continuous.


name: Diabetes Mellitus due to Underlying Condition with Proliferative Diabetic Retinopathy with Traction Retinal Detachment not Involving the Macula, Unspecified Eye

description: Evidence of diabetes mellitus due to underlying condition with proliferative diabetic retinopathy with traction retinal detachment not involving the macula in an unspecified eye.


Retinoblastoma cM1 TNM Finding v7

description: Retinoblastoma with systemic metastasis. (from AJCC 7th Ed.)


Donor Retested Negative

description: A test result of negative infectious disease markers at subsequent testing of blood products that have been stored for a minimum of 112 days.


Grade 2 Fecal Incontinence, CTCAE

description: Daily use of pads required


Grade 2 Duodenal Perforation, CTCAE

description: Invasive intervention not indicated


name: Major Salivary Gland Cancer pTX TNM Finding v8

description: Major salivary gland cancer in which the primary tumor cannot be assessed. (from AJCC 8th Ed.)


name: Progressive Disease by Computed Tomography

description: There is an increase in the size and extent of tissue involvement by cancer, based on CT scan and criteria-defined assessments.


Grade 1 Belching, CTCAE

description: Increase from baseline


name: Grade 3 Catheter-Related Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


Infantile Apnea, AE

description: An adverse event in a newborn characterized by cessation of air flow.


Adenocarcinoma of Unknown Primary

description: An adenocarcinoma which has metastasized from an unknown primary anatomic site.


name: Low Grade Prostatic Intraepithelial Neoplasia

description: Prostatic intraepithelial neoplasia characterized by the proliferation of secretory cells with irregular spacing in the ducts and acini.  Although some proliferating epithelial cells may contain prominent nucleoli, the cytologic atypia and architectural growth patterns that are seen in the high grade prostatic intraepithelial neoplasia are absent.  The presence of low grade prostatic intraepithelial neoplasia in needle biopsy is not a risk factor for the subsequent detection of carcinoma on repeat biopsy.


name: Stage IV Ampulla of Vater Cancer AJCC v8

description: Stage IV includes: Any T, Any N, M1. M1: Distant metastasis. (AJCC 8th ed.)


Recurrent WHO Grade 2 Glioma

description: The reemergence of WHO grade 2 glioma after a period of remission.


Testicular Cancer pT0 TNM Finding v8

description: Testicular cancer with no evidence of primary tumor. (from AJCC 8th Ed.)


name: Major Salivary Gland Cancer TNM Finding v6

description: A finding about one or more characteristics of major salivary gland cancer, following the rules of the TNM AJCC v6 classification system.


Grade 3 Colonic Perforation, CTCAE

description: Invasive intervention indicated


name: Grade 2 Lens Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


Minor Response in Neuroblastoma

description: Partial response or complete response in at least one component (i.e., soft tissue, bone, and bone marrow disease) but at least one other component with stable disease; no component with progressive disease. (J Clin Oncol 35: 2580-2587, 2017)


Testicular Cancer pNX TNM Finding v8

description: Testicular cancer in which the regional lymph nodes cannot be assessed. (from AJCC 8th Ed.)


Alkalosis, CTCAE

description: A disorder characterized by abnormally high alkalinity (low hydrogen-ion concentration) of the blood and other body tissues.


description: Evidence of alcohol dependence with intoxication delirium.


Hypercholesterolemia

description: A laboratory test result indicating an increased amount of cholesterol in the blood.


Recurrent Glioma

description: The reemergence of a glioma after a period of remission.


HBV DNA Level Finding

description: The viral load of hepatitis b virus DNA units in a blood sample.


CD5 Negative

description: An indication that CD5 expression has not been detected in a sample.


name: Grade 1 Cranial Nerve IX Motor Intra-Operative Injury, CTCAE


name: Chronic drug-induced interstitial lung disorders

description: Evidence of chronic drug-induced interstitial lung disorders.


Most Recent Disease Relapse

description: The latest relapse of the disease.


name: Grade 1 Face NOS Intra-Operative Injury, CTCAE


name: Adult Acute Myeloid Leukemia with t(8;21); (q22; q22.1); RUNX1-RUNX1T1

description: An acute myeloid leukemia with t(8;21)(q22; q22.1); RUNX1-RUNX1T1 occurring in adults.


name: Grade 2 Wound Infection with Unknown Absolute Neutrophil Count, CTCAE


Self-Injury

description: Self-inflicted harm without the intent to die.


Increased Corpora Lutea

description: An increase in the number of corpora lutea within the ovary.


name: Pathologic Stage IIB Merkel Cell Carcinoma AJCC v8

description: Stage IIB includes: T4, N0, M0. T4: Primary tumor invades fascia, muscle, cartilage, or bone. N0: No regional lymph node metastasis detected on pathologic examination. M0: No distant metastasis detected on clinical and/or radiologic examination. (AJCC 8th ed.)


name: Intracranial and intraspinal phlebitis and thrombophlebitis

description: Evidence of intracranial and intraspinal phlebitis and thrombophlebitis.


Diagnosis Not Present at Admission

description: An indication that a diagnosed condition was not evident at admission.


Superficial Lesion

description: A lesion with limited invasion of deeper tissues.


Cervical Cancer cT1b2 TNM Finding v7

description: Invasive cervical cancer with clinically visible lesion more than 4.0 cm in greatest dimension confined to the cervix. (from AJCC 7th Ed.)


name: Small Intestine Cancer Pathologic TNM Finding v8

description: A pathologic finding about one or more characteristics of small intestine cancer, following the rules of the TNM AJCC v8 classification system.


Skin Induration, CTCAE

description: A disorder characterized by an area of hardness in the skin.


name: Grade 4 Bronchus Infection with Unknown Absolute Neutrophil Count, CTCAE


name: Grade 5 Radiation Recall Reaction (Dermatologic), CTCAE

description: Death


name: Paratesticular Well Differentiated Papillary Mesothelial Tumor

description: A rare, indolent, usually solitary mesothelial neoplasm that arises from the tunica vaginalis. It is characterized by the presence of a papillary architecture in which the papillae are lined by cuboidal mesothelial cells. Mitotic figures are usually absent. Stromal invasion is absent or minimal. It usually manifests with a hydrocele and less frequently scrotal mass.


Herpes esophagitis

description: Esophagitis resulting from exposure to herpes virus.


Stage IIIB Cervical Cancer AJCC v9

description: Stage IIIB includes: T3b, N0, M0. T3b: Tumor extending to pelvic wall and/or causing hydronephrosis or nonfunctioning kidney (unless known to be due to another cause). N0: No regional lymph node metastasis. M0: No distant metastasis. (from AJCC 9th Ed.)


Bone Epithelioid Hemangioendothelioma

description: A low-grade malignant blood vessel neoplasm arising from the bone.  It is characterized by the presence of epithelioid endothelial cells.  The neoplastic cells are arranged in cords and nests, which are embedded in a myxoid to hyalinized stroma.


name: Grade 2 Lung Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


name: Major Salivary Gland Cancer Clinical TNM Finding v7

description: A clinical finding about one or more characteristics of major salivary gland cancer, following the rules of the TNM AJCC v7 classification system.  The assessment of primary salivary gland tumors includes a pertinent history, (pain, trismus, etc.), inspection, palpation, and evaluation of the cranial nerves.  Radiologic studies may add information valuable for staging.  (from AJCC 7th Ed.)


Cutaneous Melanoma TNM Finding v6

description: A finding about one or more characteristics of cutaneous melanoma, following the rules of the TNM AJCC v6 classification system.


Bladder Cancer by AJCC v8 Stage

description: A term that refers to the staging of bladder cancer according to the American Joint Committee on Cancer, 8th edition. This staging system applies to carcinomas arising in the bladder. The typical carcinoma of the bladder is urothelial carcinoma. These carcinomas may include other histologic elements, including adenocarcinoma, squamous cell carcinoma, and small cell neuroendocrine carcinoma, but should be classified as urothelial unless the cancer is composed entirely of the alternative histology. All histologic cell types that are derived primarily from the urinary bladder epithelium should follow this staging system. It does not apply to prostatic urothelial carcinomas (are staged according to the classification for urethra), lymphomas (are staged according to the classification for Hodgkin and non-Hodgkin lymphoma), and sarcomas (are staged according to the classification for soft tissue sarcoma of the abdomen and thoracic visceral organs).  (from AJCC 8th Ed.)


name: Cerebral Infarction due to Unspecified Occlusion or Stenosis of Unspecified Cerebral Artery

description: Evidence of cerebral infarction due to an unspecified occlusion or stenosis of an unspecified cerebral artery.


Bronchial Fistula

description: An abnormal communication between the bronchus and another organ or anatomic site.


name: Advanced Gastric Large Cell Neuroendocrine Carcinoma

description: A gastric large cell neuroendocrine carcinoma that has spread extensively to other anatomic sites or is no longer responding to treatment.


Grade 4 Pleural Effusion, CTCAE

description: Life-threatening respiratory or hemodynamic compromise; intubation or urgent intervention indicated


name: Type 1 Diabetes Mellitus with Diabetic Chronic Kidney Disease

description: Evidence of type 1 diabetes mellitus with diabetic chronic kidney disease.


name: Other Non-Rheumatic Aortic Valve Disorders

description: Evidence of other non-rheumatic aortic valve disorders not specified elsewhere.


name: Type IV Total Anomalous Pulmonary Venous Return

description: Total anomalous pulmonary venous return in which the right and left pulmonary arteries drain into different sites.


name: Refractory Endometrial Mucinous Adenocarcinoma

description: Endometrial mucinous adenocarcinoma that is resistant to treatment.


name: Merkel Cell Carcinoma pN0 TNM Finding v7

description: Merkel cell carcinoma with negative regional lymph nodes by pathologic examination. (from AJCC 7th Ed.)


name: Type 1 Diabetes Mellitus with Proliferative Diabetic Retinopathy without Macular Edema, Bilateral

description: Evidence of type 1 diabetes mellitus with proliferative diabetic retinopathy without macular edema that is bilateral.


Endocarditis Infective, CTCAE

description: A disorder characterized by an infectious process involving the endocardial layer of the heart.


Testicular Cancer cM1a TNM Finding v7

description: Testicular cancer with non-regional nodal or pulmonary metastasis. (from AJCC 7th Ed.)


name: Grade 5 Atrioventricular Block Complete, CTCAE

description: Death


name: Eyelid Carcinoma Pathologic Distant Metastasis TNM Finding v8

description: A pathologic finding about one or more characteristics of eyelid carcinoma, following the rules of the TNM AJCC v8 classification system as they pertain to distant metastases.


Adenocarcinoma of the prostate stage I

description: Stage I includes: (T1a-c, N0, M0, PSA less than 10, Gleason equal or less than 6); (T2a, N0, M0, PSA less than 10, Gleason equal or less than 6); (T1-2a, N0, M0, PSA X, Gleason X).  T1a: Tumor incidental histologic finding in 5% or less of tissue resected.  T1b: Tumor incidental histologic finding in more than 5% of tissue resected.  T1c: Tumor identified by needle biopsy (e.g., because of elevated PSA).  T2a: Tumor involves one-half of one lobe or less. cN0: No regional lymph node metastasis.  pN0: No positive regional nodes.  M0: No distant metastasis.  Gleason Equal or Less than 6: Well differentiated (slight anaplasia).  Gleason X: Gleason score cannot be processed.  (AJCC 7th ed.)


name: Grade 1 Pelvic Floor Muscle Weakness, CTCAE

description: Asymptomatic; clinical or diagnostic observations only; intervention not indicated


Grade 2 Urinary Retention, CTCAE

description: Placement of urinary, suprapubic or intermittent catheter placement indicated; medication indicated


Stage IA Bone Cancer AJCC v7

description: Stage IA includes: T1, N0, M0, G1, G2, GX.  T1: Tumor 8 cm or less in greatest dimension.  N0: No regional lymph node metastasis.  M0: No distant metastasis. G1: Well differentiated-low grade.  G2: Moderately differentiated-low grade.  GX: Grade cannot be assessed. (AJCC 7th ed.)


Breast Cancer pN0(i+) TNM Finding v7

description: Breast cancer with malignant cells in regional lymph node(s) no greater than 0.2 mm (detected by H&E or immunohistochemistry including isolated tumor cell clusters).  (from AJCC 7th Ed.)


name: Grade 3 Biliary Tree Common Hepatic Duct Intra-Operative Injury, CTCAE


name: Other specified peripheral vascular diseases

description: Evidence of other specified peripheral vascular diseases not specified elsewhere.


lymphomatoid papulosis, type A

description: A variant of lymphomatoid papulosis characterized by the presence of scattered anaplastic large lymphocytes, often resembling Reed-Sternberg cells, admixed with acute and chronic inflammatory cells.


Intra-Abdominal Paraganglioma

description: An extra-adrenal paraganglioma arising from the abdominal cavity.


name: Death Due to Disease Progression Not Associated with More Specific Term NOS, CTCAE


name: Pancreatic Neuroendocrine Tumor by AJCC v8 Stage

description: A term that refers to the staging of a pancreatic neuroendocrine tumor, following the rules of the TNM AJCC v8 classification system. This staging system applies to well-differentiated neuroendocrine tumors arising in the pancreas. Carcinomas of the pancreas, including high-grade (grade 3), poorly differentiated neuroendocrine carcinomas are not staged using this staging system. (from AJCC 8th Ed.)


name: Unspecified Diabetes Mellitus in Pregnancy, Third Trimester

description: Evidence of unspecified diabetes mellitus in pregnancy in the third trimester.


name: Adult Dysembryoplastic Neuroepithelial Tumor

description: A dysembryoplastic neuroepithelial tumor that occurs during adulthood.


name: Grade 5 Peripheral Arterial Ischemia, CTCAE


Complete Hematologic Response

description: The disappearance of cancer in response to treatment, including platelet and white blood cell counts returning to normal levels, a non-palpable spleen, and no immature white blood cells present in the blood unless it is a regenerating marrow following treatment.


name: Colorectal Neuroendocrine Tumor Pathologic Distant Metastasis TNM Finding v8

description: A pathologic finding about one or more characteristics of a colorectal neuroendocrine tumor, following the rules of the TNM AJCC v8 classification system as they pertain to distant metastases.


Anal Cancer TNM Finding v8

description: A finding about one or more characteristics of anal cancer, following the rules of the TNM AJCC v8 classification system. This staging system applies to all carcinomas arising in the anal canal, including carcinomas that arise within anorectal fistulas and those arising in the perianal area (anal margin). High-grade neuroendocrine carcinomas (small cell neuroendocrine carcinoma and large cell neuroendocrine carcinoma) are staged using this system. There is no AJCC staging system for anal mucosal melanomas and anal well-differentiated neuroendocrine tumors. (from AJCC 8th Ed.)


Stage III Gallbladder Cancer AJCC v7

description: Stage III includes: IIIA (T3, N0, M0); IIIB (T1-3, N1, M0). T3: Tumor perforates the serosa (visceral peritoneum) and/or directly invades the liver and/or one other adjacent organ or structure, such as the stomach, duodenum, colon, pancreas, omentum, or extrahepatic bile ducts.  T1: Tumor invades lamina propria or muscular layer.  T2: Tumor invades perimuscular connective tissue; no extension beyond serosa or into liver. N0: No regional lymph node metastasis.  N1: Metastases to nodes along the cystic duct, common bile duct, hepatic artery, and/or portal vein.  M0: No distant metastasis. (from AJCC 7th Ed.)


name: Non-T Non-B CALLA Negative Adult Acute Lymphoblastic Leukemia

description: Non-T non-B, CALLA negative acute lymphoblastic leukemia that occurs during adulthood.


name: Metastatic Human Papillomavirus-Related Malignant Neoplasm

description: A malignant neoplasm that is associated with human papillomavirus infection and has spread from its original site of growth to another anatomic site.


Grade 4 Retinopathy of Prematurity, AE

description: An adverse event in a newborn characterized by unilateral retinal detachment.


Adult Ependymal Tumor

description: An ependymal tumor of the central nervous system occurring in adults.


Dust Exposure

description: Exposure to any type of airborne particulate matter.


name: Rheumatoid Arthritis with Rheumatoid Factor of Unspecified Hip without Organ or Systems Involvement

description: Evidence of rheumatoid arthritis with rheumatoid factor of unspecified hip without organ or systems involvement.


Grade 3 Heart Failure, CTCAE

description: Symptoms at rest or with minimal activity or exertion; hospitalization; new onset of symptoms


Impatent structure

description: A congenital anatomic defect characterised by the absence of a normally present opening in an organ or tissue.


Stage IIIA Appendix Carcinoma AJCC v7

description: Stage IIIA includes: (T1, N1, M0); (T2, N1, M0). T1: Tumor invades submucosa.  T2: Tumor invades muscularis propria. N1: Metastasis in 1-3 regional lymph nodes.  M0: No distant metastasis.  (AJCC 7th ed.)


P3 Hydronephrosis

description: Postnatal Hydronephrosis with the following clinical findings: 1) calyceal dilation and the ureter are the same as those in UTD P2, 2) the renal parenchymal is thinned, has increased echogenicity and/or has decreased corticomedullary differentiation, or 3) the bladder is abnormal (wall thickening, ureterocele, posterior urethral dilation). Cases in which there are parenchymal abnormalities but the APRPD is less than 15 mm, are classified as UTD P3. (Adapted from: Hiep T. Nguyen, Carol B. Benson, Bryann Bromley, Jeffrey B. Campbell, Jeanne Chow, Beverly Coleman, Christopher Cooper, Jude Crino, Kassa Darge, C.D. Anthony Herndon, Anthony O. Odibo, Michael J.G. Somers, Deborah R. Stein; Multidisciplinary consensus on the classification of prenatal and postnatal urinary tract dilation (UTD classification system); Pediatric Urology; December 2014 Volume 10, Issue 6, Pages 982-998)


name: Primary Intraosseous Squamous Cell Carcinoma-Solid Type

description: A non-keratinizing or keratinizing squamous cell carcinoma that arises centrally from the jaw.  It is characterized by a solid pattern, infiltration of the marrow spaces, and osseous resorption.


Subsequent Relapse

description: The reemergence of a disorder as diagnosed by clinical and/or laboratory evidence following two or more documented periods of remission.


Tumor associated fever

description: Non-infectious pyrexia secondary to malignancy; it may be attributable to cytokines elaborated by neoplasms, and is a diagnosis of exclusion.


Tumor Hemorrhage, CTCAE

description: A disorder characterized by bleeding in a tumor.


name: Type 2 Diabetes Mellitus with Other Circulatory Complications

description: Evidence of type 2 diabetes mellitus with other circulatory complications.


Ureter Urothelial Carcinoma, High Grade

description: Ureter urothelial carcinoma characterized by the presence of neoplastic epithelial cells with high grade features.


name: Stage IIIC2 Uterine Corpus Cancer AJCC v8

description: Stage IIIC2 includes: T1-T3, N2/N2mi/N2a, M0. T1: Uterine corpus carcinoma or carcinosarcoma with tumor confined to the corpus uteri, including endocervical glandular involvement. T2: Uterine corpus carcinoma or carcinosarcoma with tumor invading the stromal connective tissue of the cervix but not extending beyond the uterus. Does not include endocervical glandular involvement. T3: Uterine corpus carcinoma or carcinosarcoma with tumor involving serosa, adnexa, vagina, or parametrium. N2: Regional lymph node metastasis to para-aortic lymph nodes, with or without positive pelvic lymph nodes. N2mi: Regional lymph node metastasis (greater than 0.2 mm but not greater than 2.0 mm in diameter) to para-aortic lymph nodes, with or without positive pelvic lymph nodes. N2a: Regional lymph node metastasis (greater than 2.0 mm in diameter) to para-aortic lymph nodes, with or without positive pelvic lymph nodes. M0: No distant metastasis. (from AJCC 8th Ed.)


name: Gastric ulcer, chronic or unspecified with both hemorrhage and perforation

description: Evidence of chronic or unspecified gastric ulcer with both hemorrhage and perforation.


Grade 2 Sleep Apnea, CTCAE

description: Moderate apnea and oxygen desaturation; excessive daytime sleepiness; medical evaluation indicated; limiting instrumental ADL


Neck Mass

description: An abnormal growth in the neck.


name: Uterine Corpus Carcinoma Clinical TNM Finding v7

description: A clinical finding about one or more characteristics of uterine corpus carcinoma, following the rules of the TNM AJCC v7 classification system. TNM clinical findings are based on information obtained prior to the first definitive treatment through physical examination, diagnostic imaging, biopsy and laboratory testing.


Grade 4 Cranial Nerve Infection, CTCAE

description: Life-threatening consequences; urgent intervention indicated


Necrotizing Enterocolitis, AE

description: An adverse event in newborns characterized by extensive mucosal ulceration, pseudomembrane formation, submucosal hemorrhage, and necrosis in the intestines .


Stage II Childhood Large Cell Lymphoma

description: Stage II: Involvement of two or more lymph node regions on the same side of the diaphragm (II) or localized involvement of a single associated extralymphatic organ or site and its regional lymph nodes with or without other lymph node regions on the same side of the diaphragm (IIE). Note: The number of lymph node regions involved may be indicated by a subscript (e.g., II3). (from PDQ)


Colorectal Cancer pN2 TNM Finding v7

description: Colorectal cancer with metastasis in four or more regional lymph nodes. (from AJCC 7th Ed.)


Grade 3 Bronchial Obstruction, CTCAE

description: Shortness of breath with stridor; endoscopic intervention indicated (e.g., laser, stent placement)


name: Grade 1 Cranial Nerve II Intra-Operative Injury, CTCAE


Disease Progression, CTCAE

description: Death due to disease progression that cannot be attributed to a CTCAE term associated with Grade 5.


name: Diabetes Mellitus due to Underlying Condition with Ketoacidosis without Coma

description: Evidence of diabetes mellitus due to underlying condition with ketoacidosis without coma.


Positive Rechallenge Response

description: Recurrence of similar or new signs or symptoms upon reintroduction of the product/drug.


Grade 4 Ileal Obstruction, CTCAE

description: Life-threatening consequences; urgent operative intervention indicated


name: Testicular Sex Cord-Gonadal Stromal Tumor, Incompletely Differentiated

description: A sex cord-stromal tumor of the testis in which the neoplastic cells do not show specific differentiation.


name: Refractory Microsatellite Stable Endometrial Carcinoma

description: Microsatellite stable endometrial carcinoma that is resistant to treatment.


Subgaleal haematoma

description: A collection of blood between the scalp and the skull periosteum.


Naso-palatine duct cyst

description: A non-odontogenic cyst of developmental origin that arises in the midline of the anterior maxilla. It is found exclusively in the midline of the anterior hard palate. (WHO 2017)


name: Other Thyrotoxicosis with Thyrotoxic Crisis or Storm

description: Evidence of other thyrotoxicosis with thyrotoxic crisis or storm not specified elsewhere.


Absent Adverse Event

description: The absence of adverse events or within normal limits or values.


name: Grade 5 Bronchospasm and Wheezing, CTCAE


Grade 4 Pharyngeal Stenosis, CTCAE

description: Life-threatening airway compromise; urgent intervention indicated (e.g., tracheotomy or intubation)


name: Cerebral Infarction due to Embolism of Other Cerebral Artery

description: Evidence of cerebral infarction due to an embolism of other cerebral artery.


name: Other Specified Diabetes Mellitus with Proliferative Diabetic Retinopathy with Traction Retinal Detachment Involving the Macula, Bilateral

description: Evidence of other specified diabetes mellitus with proliferative diabetic retinopathy with traction retinal detachment involving the macula that is bilateral not specified elsewhere.


name: Grade 3 Brain Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


Malignant lymphoma, diffuse

description: An antiquated term referring to non-Hodgkin lymphomas with a diffuse architectural pattern.


Other lymphoid leukemia, in remission

description: Evidence of other lymphoid leukemia in remission not specified elsewhere.


Neonatal Bradyarrhythmia, AE

description: An adverse event in a newborn characterized by non-sinus rhythm with an abnormally low heart rate for age.


name: Grade 5 Appendix Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


name: Retinopathy of Prematurity with Plus Disease

description: A stage of retinopathy of prematurity characterized by the presence of the following in at least two quadrants around the optic nerve: dilation and tortuosity of major retinal vasculature as a result of increased blood flow.


name: Grade 2 Sinus Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


Fallopian Tube Perforation, CTCAE 5.0

description: A disorder characterized by a rupture of the fallopian tube wall.


name: Ampulla of Vater Undifferentiated Carcinoma with Osteoclast-Like Giant Cells

description: A rare variant of undifferentiated carcinoma that arises from the ampulla of Vater. It is characterized by the presence of non-neoplastic, histiocytic, osteoclast-like multinucleated giant cells.


name: Adrenal Cortical Carcinoma TNM Finding v8

description: A finding about one or more characteristics of adrenal cortical carcinoma, following the rules of the TNM AJCC v8 classification system. Adrenal medullary pheochromocytoma is staged according to the classification for adrenal neuroendocrine tumors. There is no AJCC staging system for neuroblastic tumors of the adrenal gland. (from AJCC 8th Ed.)


Hashish Smoke Exposure

description: Environmental, occupational or consumer-based exposure to airborne gases and particulates produced by direct or nearby use of a vaporized or combusted product made from cannabis plant resin.


name: High-Grade Squamous Intraepithelial Lesions

description: A precancerous neoplastic process characterized by the presence of moderate or severe dysplastic cytological changes which extend to the upper part of the squamous epithelium.  Maturation at the surface of the squamous epithelium may or may not be present.  Representative examples include the high grade esophageal squamous intraepithelial neoplasia, high grade cervical squamous intraepithelial neoplasia, high grade vaginal intraepithelial neoplasia, and high grade vulvar intraepithelial neoplasia.


name: Uterine Corpus Adenosarcoma Pathologic TNM Finding v8

description: A pathologic finding about one or more characteristics of uterine corpus adenosarcoma, following the rules of the TNM AJCC v8 classification system.


name: Grade 2 Pancreas Infection with Unknown Absolute Neutrophil Count, CTCAE


Grade 1 Voice Alteration, CTCAE

description: Mild or intermittent change from normal voice


name: Grade 5 Lens Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


name: Grade 2 Trachea Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


name: Solar Radiation-Related Skin Squamous Cell Carcinoma

description: A squamous cell carcinoma arising in a skin site exposed to solar radiation.


name: Diabetes Mellitus due to Underlying Condition with Proliferative Diabetic Retinopathy with Traction Retinal Detachment Involving the Macula, Left Eye

description: Evidence of diabetes mellitus due to underlying condition with proliferative diabetic retinopathy with traction retinal detachment involving the macula in the left eye.


Volcanic Smoke Exposure

description: Environmental exposure to airborne gases and particulates produced by a volcanic event.


name: Reactive attachment disorder of infancy or early childhood

description: A condition in which the failure to establish healthy bonds with caregivers in early childhood leads to lifelong impairment of social interactions.


name: Rheumatoid Arthritis without Rheumatoid Factor, Left Hip

description: Evidence of rheumatoid arthritis without rheumatoid factor in the left hip.


name: Locally Advanced Malignant Solid Neoplasm

description: A malignant solid neoplasm that has spread from its original site of growth to nearby tissues or lymph nodes.


Sexually Transmitted Chlamydial Disease

description: A chlamydial infection that was sexually transmitted.


Grade 1 Penile Pain, CTCAE

description: Mild pain


name: Glottic Cancer Pathologic Primary Tumor TNM Finding v8

description: A pathologic finding about one or more characteristics of glottic cancer, following the rules of the TNM AJCC v8 classification system as they pertain to staging of the primary tumor.


name: Pre-Existing Hypertensive Heart and Chronic Kidney Disease Complicating Pregnancy, Third Trimester

description: Evidence of pre-existing hypertensive heart and chronic kidney disease complicating pregnancy in the third trimester.


name: Recurrent Malignant Genitourinary System Neoplasm

description: The reemergence of a malignant genitourinary system neoplasm after a period of remission.


Intracranial Hemorrhage, CTCAE

description: A disorder characterized by bleeding from the cranium.


name: Melanoma in Situ of Unspecified Ear and External Auricular Canal

description: Evidence of melanoma in situ of unspecified ear and external auricular canal.


Reactive arthropathy

description: Evidence of reactive arthropathy.


name: Nasal Cavity and Ethmoid Sinus Cancer TNM Finding v7

description: A finding about one or more characteristics of nasal cavity and ethmoid sinus cancer, following the rules of the TNM AJCC v7 classification system.


Unresectable Gastric Adenocarcinoma

description: A gastric adenocarcinoma that is not amenable to surgical resection.


Grade 4 Urinary Tract Infection, CTCAE

description: Life-threatening consequences; urgent intervention indicated


MPO Negative

description: An indication that expression of MPO has not been detected in a sample.


Breast Cancer cN1mi TNM Finding v8

description: Breast cancer with micrometastases (approximately 200 cells, larger than 0.2 mm, but none larger than 2.0 mm). cN1mi is rarely used but may be appropriate in cases where sentinel node biopsy is performed before tumor resection, most likely to occur in cases treated with neoadjuvant therapy. (from AJCC 8th Ed.)


Grade 2 Weight Gain, CTCAE

description: 10-<20% from baseline


name: Diabetes Mellitus due to Underlying Condition with Diabetic Chronic Kidney Disease

description: Evidence of diabetes mellitus due to underlying condition with diabetic chronic kidney disease.


Lungs Partial Response GvHD

description: Either an increase by 10% predicted absolute value of %FEV1 or an NIH lung symptom score that has decreased by 1 or more points.


Enteropathogenic E coli Infection

description: A pathotype of Escherichia coli, which is a gram-negative bacteria that is transmitted through the fecal-oral route. It has an incubation period of 9-12 hours and a duration of 12 days. Symptoms may include persistent severe acute diarrhea.


name: Gastric Cancer Pathologic Primary Tumor TNM Finding v7

description: A pathologic finding about one or more characteristics of gastric cancer, following the rules of the TNM AJCC v7 classification system as they pertain to staging of the primary tumor.


name: Rectum Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


name: Grade 2 Salivary Gland Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


Biliary Fistula

description: An abnormal communication between the bile ducts and another organ or cavity.


name: Mucosal Melanoma of the Head and Neck Pathologic Regional Lymph Nodes TNM Finding v7

description: A pathologic finding about one or more characteristics of mucosal melanoma of the head and neck, following the rules of the TNM AJCC v7 classification system as they pertain to staging of regional lymph nodes.


Gastric Cancer pT4 TNM Finding v7

description: Gastric cancer with tumor invading serosa (visceral peritoneum) or adjacent structures.  The adjacent structures of the stomach include the spleen, transverse colon, liver, diaphragm, pancreas, abdominal wall, adrenal gland, kidney, small intestine, and retroperitoneum.  Intramural extension to the duodenum or esophagus is classified by the depth of the greatest invasion in any of these sites, including the stomach. (from AJCC 7th Ed.)


Spindle Cell/Pleomorphic Lipoma

description: A benign lipomatous neoplasm characterized by the presence of an admixture of mature adipose tissue and bland spindle cells.  The pleomorphic variant contains in addition multinucleated giant cells.  It usually arises in the neck and upper trunk in older males.


name: Cerebral Infarction due to Embolism of Unspecified Middle Cerebral Artery

description: Evidence of cerebral infarction due to an embolism of an unspecified middle cerebral artery.


Grade 5 Urinary Fistula, CTCAE

description: Death


Grade 2 Bronchial Fistula, CTCAE

description: Symptomatic, invasive intervention not indicated


name: Stage IIIC1 Uterine Corpus Cancer AJCC v7

description: Stage IIIC1 includes: T1-T3, N1, M0.  T1: Tumor confined to corpus uteri.  T2: Tumor invades stromal connective tissue of the cervix but does not extend beyond uterus.  T3: Tumor involves serosa and/or adnexa, vagina, or parametrial tissue. N1: Regional lymph node metastasis to pelvic lymph nodes. M0: No distant metastasis. This staging applies to carcinomas and carcinosarcomas. (AJCC 7th ed.)


Grade 2 Dysphasia, CTCAE

description: Moderate receptive or expressive characteristics; impairing ability to communicate spontaneously


name: Grade 2 Pancreatic Duct Intra-Operative Injury, CTCAE


Capsular Contracture

description: The tightening of scar tissue that forms around the implant.


Stage II Skin Cancer

description: Stage II includes: T2, N0, M0.  T2: Tumor size greater than 2 cm in greatest dimension or tumor of any size with two or more high-risk features.  High-risk features for the primary tumor staging are defined as follows: depth/invasion of more than 2 mm thickness; Clark level equal or greater than IV; and perineural invasion.  Anatomic location: primary site ear and primary site non-hair-bearing lip.  Differentiation: poorly differentiated or undifferentiated.  N0: No regional lymph node metastasis.  M0: No clinical or radiographic evidence of distant metastasis.  (AJCC 7th ed.)


name: Grade 2 Spinal Cord Infection with Unknown Absolute Neutrophil Count, CTCAE


name: Grade 1 Ureter Intra-Operative Injury, CTCAE


name: Grade 1 Bone Growth Limb Length Discrepancy, CTCAE


name: Sarcoma of the Orbit Pathologic Distant Metastasis TNM Finding v7

description: A pathologic finding about one or more characteristics of sarcoma of the orbit, following the rules of the TNM AJCC v7 classification system as they pertain to distant metastases.  There is no pathologic M0 for sarcoma of the orbit. (from AJCC 7th Ed.)


Vaginal Cancer pT1a TNM Finding v8

description: Vaginal cancer with tumor confined to the vagina, measuring 2.0 cm or less. (from AJCC 8th Ed.)


Leakage

description: The unintentional discharge of a substance from a container or enclosed space.


Grade 4 Skin Ulceration, CTCAE

description: Any size ulcer with extensive destruction, tissue necrosis, or damage to muscle, bone, or supporting structures with or without full thickness skin loss


Refractory Pseudomyxoma Peritonei

description: Pseudomyxoma peritonei that is resistant to treatment.


Condylomatous carcinoma

description: A squamous cell carcinoma characterized by a papillary growth pattern, hyperkeratosis, and koilocytosis.


Advanced Glioblastoma

description: Glioblastoma that has spread extensively to other anatomic sites or is no longer responding to treatment.


Insufficient DNA Yield

description: An indication that a DNA isolation procedure yielded an insufficient amount of DNA to proceed.


name: Grade 4 Recurrent Laryngeal Nerve Palsy, CTCAE

description: Life-threatening consequences; urgent intervention indicated


Grade 3 Bladder Perforation, CTCAE

description: Invasive intervention indicated


Corn of toe

description: A thickening of the skin due to friction or pressure which results in the formation of a small, painful, raised bump associated with a conical mass pointing down into the dermis.


name: Rheumatoid Myopathy with Rheumatoid Arthritis of Unspecified Shoulder

description: Evidence of rheumatoid myopathy with rheumatoid arthritis of unspecified shoulder.


name: Grade 3 Non-Infectious Wound Complication, CTCAE


name: Duodenum and Ampulla of Vater Neuroendocrine Tumor Clinical TNM Finding v8

description: A clinical finding about one or more characteristics of a duodenum and ampulla of Vater neuroendocrine tumor, following the rules of the TNM AJCC v8 classification system.


name: Grade 5 Dental-Tooth Infection with Unknown Absolute Neutrophil Count, CTCAE


Stomal Ulcer, CTCAE 5.0

description: A disorder characterized by a circumscribed, erosive lesion on the jejunal mucosal surface close to the anastomosis site following a gastroenterostomy procedure.


name: Grade 5 Fallopian Tube Perforation, CTCAE

description: Death


name: Grade 1 Bladder Intra-Operative Injury, CTCAE


Glottic Cancer pTX TNM Finding v8

description: Glottic cancer in which the primary tumor cannot be assessed. (from AJCC 8th Ed.)


name: K ATP Channel-Associated Diabetes Mellitus

description: Diabetes mellitus caused by activating mutation(s) in genes (KNCJ11 and/or ABCC8) encoding either of the 2 proteins (Kir6.2 and/or SUR1) that make up the pancreatic beta cell adenosine triphosphate-sensitive potassium channel, which is crucial for the regulation of glucose-induced insulin secretion.


name: Malignant Neoplasm of Unspecified Site of Right Male Breast

description: Evidence of a malignant neoplasm of an unspecified site of right male breast.


name: Prostate Cancer Pathologic Regional Lymph Nodes TNM Finding v7

description: A pathologic finding about one or more characteristics of prostate cancer, following the rules of the TNM AJCC v7 classification system as they pertain to staging of regional lymph nodes.  (from AJCC 7th Ed.)


Grade 1 Prostatic Pain, CTCAE

description: Mild pain


name: Pathologic Stage IIIA Esophageal Adenocarcinoma AJCC v8

description: Stage IIIA includes: (T1, N2, M0, Any G); (T2, N1, M0, Any G). T1: Tumor invades the lamina propria, muscularis mucosae, or submucosa. T2: Tumor invades the muscularis propria. N1: Tumor with metastasis in one or two regional lymph nodes. N2: Tumor with metastasis in three to six regional lymph nodes. M0: No distant metastasis. (AJCC 8th ed.)


Grade 2 Jejunal Ulcer, CTCAE

description: Symptomatic; altered GI function


name: Recurrent Malignant Choroid Plexus Neoplasm

description: The reemergence of a malignant choroid plexus neoplasm after a period of remission.


Grade 2 Gingival Pain, CTCAE

description: Moderate pain interfering with oral intake


name: Malignant neoplasm of connective and soft tissue, unspecified

description: Evidence of a malignant neoplasm of the connective and soft tissue.


name: Extrahepatic Bile Duct Biliary Intraepithelial Neoplasia

description: A neoplastic, non-invasive lesion that affects the extrahepatic bile duct epithelium.  It is characterized by the presence of atypical epithelial cells with an increased nuclear/cytoplasmic ratio, nuclear hyperchromasia, and loss of nuclear polarity.


name: Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma, Unspecified, Lymph Nodes of Multiple Sites

description: Evidence of an unspecified mature T-cell and NK-cell non-Hodgkin lymphoma in the lymph nodes of multiple sites.


name: Grade 3 Conjunctiva Infection with Unknown Absolute Neutrophil Count, CTCAE


Abnormal Lobation

description: The formation of a lobe of tissue that is aberrant in comparison to normal anatomy.


name: Lung Cancer Pathologic Regional Lymph Nodes TNM Finding v7

description: A pathologic finding about one or more characteristics of lung cancer, following the rules of the TNM AJCC v7 classification system as they pertain to staging of regional lymph nodes.


Regressed germ cell tumor

description: A testicular germ cell tumor that has undergone either partial or complete regression, resulting in the creation of a fibrotic nodule in the testis.


Neuroendocrine Tumor G1

description: A well-differentiated, low-grade epithelial neoplasm with neuroendocrine differentiation. It arises from multiple sites, including the digestive system, lung, and head and neck.


name: Grade 3 Sacral Plexus Intra-Operative Injury, CTCAE


name: AIDS-Related Diffuse Large B-Cell Lymphoma Arising in HHV8-Positive Multicentric Castleman Disease

description: Diffuse large B-cell lymphoma arising in HHV8-positive multicentric Castleman disease occurring in HIV-positive patients.


name: spondylopathy in diseases classified elsewhere in thoracolumbar region

description: Evidence of spondylopathy in diseases classified elsewhere in the thoracolumbar region.


name: Vulvar Squamous Cell Carcinoma with Tumor Giant Cells

description: An aggressive squamous cell carcinoma that arises from the vulva and is characterized by the prominence of malignant giant cells.


Neoplasms, Therapy-Associated

description: The development of a neoplasm in response to medical or surgical treatment, induced by the treatment itself.


name: Grade 4 Trachea Intra-Operative Injury, CTCAE


Prevertebral Abscess

description: An abscess that develops in the tissues within the prevertebral fascia.


Unresectable Esophageal Adenocarcinoma

description: Esophageal adenocarcinoma that is not amenable to surgical resection.


Positive History of COVID-19

description: A finding indicating that an individual has a history of COVID-19.


name: Ureter Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


Stage II Hodgkin Lymphoma

description: Ann Arbor Classification: Stage II: Involvement of two or more lymph node regions on the same side of the diaphragm (II); or localized involvement of a single extralymphatic organ or site in association with regional lymph node involvement with or without involvement of other lymph node regions on the same side of the diaphragm (IIE).


name: Ocular Adnexal Lymphoma pT1b TNM Finding v7

description: Palpebral conjunctiva +/- fornix +/- caruncle. (from AJCC 7th Ed.)


name: Adrenal Cortical Carcinoma pTX TNM Finding v8

description: Primary tumor cannot be assessed. (from AJCC 8th Ed.)


Grade 3 Acute Kidney Injury, CTCAE

description: Hospitalization indicated


name: Grade 4 Stomach Intra-Operative Injury, CTCAE


name: Grade 3 Stomach Stricture or Stenosis, CTCAE


Stacking Breath

description: Condition where there are a greater number of inhalations relative to the number of exhalations.


Non-Severe Aplastic Anemia

description: Aplastic anemia that is characterized by bone marrow cellularity less than 30% and does not meet criteria for severe aplastic anemia.


name: Cerebral Infarction due to Embolism of Right Middle Cerebral Artery

description: Evidence of cerebral infarction due to an embolism of the right middle cerebral artery.


name: Ocular Adnexal Lymphoma Pathologic TNM Finding v8

description: A pathologic finding about one or more characteristics of ocular adnexal lymphoma, following the rules of the TNM AJCC v8 classification system.


Serum-Ascites Albumin Gradient

description: A value determined by subtracting the concentration of albumin in ascites fluid from its concentration in the serum where both samples come from one subject. High values indicate portal hypertension and a non-peritoneal cause for ascites; while low values indicate non-portal hypertension and a peritoneal origin of ascites.


Acquired Bilateral Cataracts

description: Cataracts in both eyes that result from the aging process, an injury, or as a manifestation of a systemic disorder.


name: Unspecified Symptoms and Signs with Cognitive Functions following Other Cerebrovascular Disease

description: Evidence of unspecified symptoms and signs with cognitive functions following other cerebrovascular disease.


Grade 1 Hypoparathyroidism, CTCAE

description: Asymptomatic; clinical or diagnostic observations only; intervention not indicated


Cervical Cancer pT1b1 TNM Finding v9

description: Invasive cervical carcinoma measuring more than 5 mm in depth and equal or less than 2 cm in greatest dimension. (from AJCC 9th Ed.)


name: Nontraumatic Subarachnoid Hemorrhage from Unspecified Posterior Communicating Artery

description: Evidence of nontraumatic subarachnoid hemorrhage from unspecified posterior communicating artery.


name: Grade 1 Aorta Artery Intra-Operative Injury, CTCAE


Grade 2 Hypokalemia, CTCAE

description: Symptomatic with <LLN-3.0 mmol/L; intervention indicated


name: Grade 3 Neuroendocrine ADH Secretion Abnormality, CTCAE


name: Drug or Chemical Induced Diabetes Mellitus with Proliferative Diabetic Retinopathy with Traction Retinal Detachment not Involving the Macula, Unspecified Eye

description: Evidence of drug or chemical induced diabetes mellitus with proliferative diabetic retinopathy with traction retinal detachment not involving the macula in an unspecified eye.


Diabetes mellitus without complication

description: Diabetes mellitus that does not show any evidence of tissue or organ damage.


name: Tooth Infection with Unknown Absolute Neutrophil Count, CTCAE


name: Diabetes Mellitus due to Underlying Condition with Proliferative Diabetic Retinopathy without Macular Edema, Unspecified Eye

description: Evidence of diabetes mellitus due to underlying condition with proliferative diabetic retinopathy without macular edema in an unspecified eye.


name: Stage IA Ampulla of Vater Cancer AJCC v8

description: Stage IA includes: T1a, N0, M0. T1a: Tumor limited to ampulla of Vater or sphincter of Oddi. N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 8th ed.)


NFE2L2 Gene Mutation Negative

description: A genetic finding indicating that NFE2L2 gene mutations have not been detected in a sample.


Grade 5 Pancreatic Fistula, CTCAE

description: Death


name: Elevated Choriogonadotropin Subunit Beta

description: A finding indicating elevated concentrations of human chorionicgonadotropin subunit beta in a sample.


CA125 50% Response

description: The amount of cancer antigen 125 is reduced by 50% from protocol-defined baseline value(s).


Advanced Sarcoma of the Extremity

description: A sarcoma of the soft tissues or bones of the upper or lower extremity that has spread extensively to other anatomic sites or is no longer responding to treatment.


name: Atherosclerosis of Non-Biological Bypass Graft(s) of the Extremities with Rest Pain, Other Extremity

description: Evidence of atherosclerosis of non-biological bypass graft(s) of the extremities with rest pain in the other extremity.


Grade 3 Appendicitis Perforated, CTCAE

description: Medical intervention indicated; operative intervention indicated


Significant Intercurrent Illness

description: Any disease or disorder of relevance that occurs before, during or after another illness.


name: Unspecified Maternal Hypertension, Second Trimester

description: Evidence of unspecified maternal hypertension in the second trimester.


name: Bipolar Disorder, Current Episode Manic Severe with Psychotic Features

description: Evidence of bipolar disorder, current episode manic severe with psychotic features.


Productive Cough, CTCAE

description: A disorder characterized by expectorated secretions upon coughing.


name: Grade 1 Other Renal or Genitourinary, CTCAE


pT3 TNM Finding

description: A pathologic primary tumor TNM finding. The definition of pT3 finding depends on the particular type of cancer that it refers to; for example, for breast cancer, pT3 finding is defined as follows: cancer with tumor size more than 5.0 cm in greatest dimension; for kidney cancer, pT3 finding is defined as follows: cancer with tumor extending into major veins or perinephric tissues but not into the ipsilateral adrenal gland and not beyond Gerota's fascia. (from AJCC 7th Ed.)


name: Grade 4 Pleura Infection with Unknown Absolute Neutrophil Count, CTCAE


Serous Tubal Intraepithelial Carcinoma

description: A non-invasive serous carcinoma arising from the fallopian tube.


Birth Injuries

description: An injury sustained to a neonate during the birthing process.


Age-Related Clonal Hematopoiesis

description: The gradual, clonal expansion of hematopoietic stem and progenitor cells carrying specific, disruptive, and recurrent genetic variants, in individuals without clear diagnosis of hematological malignancies. It is associated with an increased risk of developing hematologic cancers.


T1b TNM Finding

description: A general term that refers to a TNM finding of a primary tumor limited to the site of growth.  The definition of T1b TNM finding depends on the specific type of cancer that it refers to; for example, for breast cancer it refers to a primary tumor that is more than 0.5 cm, but not more than 1.0 cm in greatest dimension; for kidney cancer it refers to a primary tumor that is more than 4 cm, but not more than 7 cm in greatest dimension; and for thyroid cancer it refers to a primary tumor that is more than 1 cm but not more than 2 cm in greatest dimension.


name: Rheumatoid Vasculitis with Rheumatoid Arthritis of Unspecified Ankle and Foot

description: Evidence of rheumatoid vasculitis with rheumatoid arthritis of unspecified ankle and foot.


Secondary Cerebral Hodgkin Lymphoma

description: A Hodgkin lymphoma that has spread to the cerebral hemisphere following the initial presentation in another nodal or extranodal site.


Other secondary hypertension

description: Evidence of other secondary hypertension not specified elsewhere.


Prostate Cancer cT1 TNM Finding v7

description: Clinically inapparent tumor neither palpable nor visible by imaging. (from AJCC 7th Ed.)


name: Grade 4 Rectum Mucositis or Stomatitis by Clinical Examination Classification, CTCAE


name: Other Specified Diabetes Mellitus with Mild Nonproliferative Diabetic Retinopathy with Macular Edema

description: Evidence of other specified diabetes mellitus with mild nonproliferative diabetic retinopathy with macular edema not specified elsewhere.


Lesion

description: A localized pathological or traumatic structural change, damage, deformity, or discontinuity of tissue, organ, or body part.


Grade 3 Injury To Carotid Artery, CTCAE

description: Severe symptoms; limiting self care ADL (e.g., transient cerebral ischemia); repair or revision indicated


name: Monoplegia, Unspecified Affecting Unspecified Side

description: Evidence of monoplegia, unspecified affecting unspecified side.


Borderline Peritoneal Serous Tumor

description: A serous epithelial tumor that arises from the peritoneum and histologically resembles the serous borderline tumors that arise from the ovary.


name: Localization-Related Symptomatic Epilepsy and Epileptic Syndromes with Complex Partial Seizures, not Intractable, without Status Epilepticus

description: Evidence of localization-related symptomatic epilepsy and epileptic syndromes with complex partial seizures without status epilepticus that responds to treatment.


Generic TNM Finding

description: A cancer finding in the TNM system that is not specifically identified as a clinical, pathologic, recurrent (retreatment), or autopsy classification using an accepted prefix in accordance with TNM classification guidelines. Though the 6th Edition of the AJCC Cancer Staging Manual indicates that unspecified TNM staging descriptors may be considered synonymous with the corresponding fully specified clinical category, such omission may lead to ambiguity in meaning, and in practice unqualified descriptors are frequently used with other intended meanings.  The generic TNM concepts in the NCI Thesaurus are intended to explicitly reflect this lack of specification.


Retinoblastoma cM1d TNM Finding v7

description: Postchiasmatic CNS lesion(s). (from AJCC 7th Ed.)


name: Grade 4 Neonatal Culture Positive Sepsis, AE

description: A culture positive sepsis adverse event in a newborn characterized by life-threatening consequences (e. g. shock, disseminated intravascular coagulation (DIC)); urgent major care change required.


name: Esophagus and Esophagogastric Junction Cancer pTis TNM Finding v7

description: Esophagus and esophagogastric junction cancer with a finding of high-grade dysplasia.  High-grade dysplasia includes all noninvasive neoplastic epithelia that was formerly called carcinoma in situ, a diagnosis that is no longer used for columnar mucosae anywhere in the gastrointestinal tract. (from AJCC 7th Ed.)


Grade 3 Bronchial Infection, CTCAE

description: IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated


name: Pathologic Stage IIC Cutaneous Melanoma AJCC v8

description: Stage IIC includes: T4b, N0, M0. T4b: Tumor measuring more than 4.0 mm in thickness. Ulceration status: With ulceration.  N0: No regional lymph node metastasis detected. Presence of in-transit, satellite, and/or microsatellite metastases: No. M0: No evidence of distant metastasis. LDH level is not applicable. (AJCC 8th ed.)


Muscle Weakness Right-Sided, CTCAE

description: A disorder characterized by a reduction in the strength of the muscles on the right side of the body.


Enteropathic Arthropathies, Left Wrist

description: Evidence of enteropathic arthropathies in the left wrist.


No Smoke Exposure

description: An indication that a subject has no history of smoke exposure from any source.


name: Other Classic Hodgkin Lymphoma, Lymph Nodes of Inguinal Region and Lower Limb

description: Evidence of other classic Hodgkin lymphoma in the lymph nodes of inguinal region and lower limb not specified elsewhere.


name: Other degenerative disorders of nervous system in diseases classified elsewhere

description: Evidence of other degenerative disorder of nervous system in disease classified elsewhere.


name: Papillary, Follicular, Hurthle Cell, Poorly Differentiated, and Anaplastic Thyroid Carcinoma cN1 TNM Finding v8

description: Metastasis to regional nodes. (from AJCC 8th Ed.)


name: Metastatic malignant neoplasm to urethra

description: A malignant neoplasm that has spread to the urethra from another anatomic site.


name: Gallbladder Cancer pT3 TNM Finding v6 and v7

description: Gallbladder cancer with tumor perforating the serosa (visceral peritoneum) and/or directly invading the liver and/or one other adjacent organ or structure, such as the stomach, duodenum, colon, pancreas, omentum, or extrahepatic bile ducts. (from AJCC 6th and 7th Eds.)


name: Grade 2 Upper Aerodigestive Infection NOS Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


name: Hemiplegia following Cerebral Infarction Affecting Left Non-Dominant Side

description: Evidence of hemiplegia following cerebral infarction affecting left non-dominant side.


Broncho-esophageal fistula

description: An abnormal connection between a bronchus and the esophagus.


Grade 3 Nasal Congestion, CTCAE

description: Associated with bloody nasal discharge or epistaxis


Inflammatory Hepatocellular Adenoma

description: A hepatocellular adenoma that occurs more often in women.  It is characterized by increased levels of inflammation-associated proteins.  It is usually associated with steatosis and obesity.


name: Grade 2 Colon Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


name: Elevated Type I Collagen Cross-Linked N-Telopeptide

description: A laboratory test result indicating the presence of an increased level of the bone resorption marker type I collagen cross-linked N-telopeptide (NTx or NTxI) in a biological sample.


Marrow Toxic Injury

description: An injury to the bone marrow resulting from exposure to high levels of ionizing radiation or exposure to other hazardous material.


Non-Obstructed Megaureter

description: A megaureter in which there is no obstruction at the ureterovesical junction.


name: Refractory Endometrial Endometrioid Adenocarcinoma

description: Endometrial endometrioid adenocarcinoma that is resistant to treatment.


Accentuation of Pulsatile Flow Artifact

description: An artifact resulting in ghost images of a vessel extending across the image in the phase encoding direction.


name: Type 2 Diabetes Mellitus with Other Oral Complications

description: Evidence of type 2 diabetes mellitus with other oral complications.


HLA Mismatch

description: The state when a recipient of a hematopoietic stem cell transplant is not fully matched with their donor for HLA-A, HLA-B, HLA-C, and HLA-DRB1.


Hepatic fibrosis with hepatic sclerosis

description: Evidence of hepatic fibrosis with hepatic sclerosis.


Colorectal Cancer pN1c TNM Finding v7

description: Colorectal cancer with tumor deposit(s) in the subserosa, mesentery, or nonperitonealized pericolic or perirectal tissues without regional lymph node metastasis. (from AJCC 7th Ed.)


Stage III Uterine Corpus Cancer AJCC v8

description: Stage III includes: T3, N0, M0. T3: Uterine corpus carcinoma or carcinosarcoma with tumor involving serosa, adnexa, vagina, or parametrium. N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 8th Ed.)


name: Arthropathy following Intestinal Bypass, Right Knee

description: Evidence of arthropathy following intestinal bypass in the right knee.


name: Colorectal Cancer Pathologic TNM Finding v7

description: A pathologic finding about one or more characteristics of colorectal cancer, following the rules of the TNM AJCC v7 classification system.  Most cancers of the colon and many cancers of the rectum are pathologically staged after surgical exploration of the abdomen, cancer-directed surgical resection, and pathologic examination of the resected specimen.  (from AJCC 7th Ed.)


name: Hepatocellular Carcinoma Clinical Distant Metastasis TNM Finding v8

description: A clinical finding about one or more characteristics of hepatocellular carcinoma, following the rules of the TNM AJCC v8 classification system as they pertain to distant metastases.


name: Mediastinal Germ Cell Tumor T1b TNM Finding

description: Mediastinal germ cell tumor confined to the organ of origin (thymus and mediastinal fat) and measuring more than 5 cm. (WHO Classification of Tumors of the Lung, Pleura, Thymus and Heart, 2015)


CSF Results

description: The results of cerebrospinal fluid laboratory tests.


name: Colorectal Neuroendocrine Tumor Clinical Distant Metastasis TNM Finding v8

description: A clinical finding about one or more characteristics of a colorectal neuroendocrine tumor, following the rules of the TNM AJCC v8 classification system as they pertain to distant metastases.


name: Follicular Lymphoma Grade II, Lymph Nodes of Axilla and Upper Limb

description: Evidence of follicular lymphoma grade II in the lymph nodes of axilla and upper limb.


name: Merkel Cell Carcinoma cT4 TNM Finding v8

description: Merkel cell carcinoma with primary tumor invading fascia, muscle, cartilage, or bone. (from AJCC 8th Ed.)


name: Unresectable Anal Canal Squamous Cell Carcinoma

description: Anal canal squamous cell carcinoma that is not amenable to surgery.


Urinary System Carcinoma

description: A malignant neoplasm that arises from the epithelium of any part of the urinary system. Representative examples include kidney carcinoma and bladder carcinoma.


Recto-Vesico-Vaginal Fistula

description: An abnormal communication between the rectum, bladder, and vagina.


name: Chest Pain Along Right Lower Sternal Border

description: The location of the chest pain is along the right lower border of the sternum.


Grade 3 Laryngeal Mucositis, CTCAE

description: Severe pain; severely altered eating/swallowing; medical intervention indicated


Broad Ligament Serous Adenofibroma

description: A rare serous adenofibroma arising from the broad ligament.


Chief Complaint

description: The primary reason for a patient visit.


name: Subglottic Cancer pM1 TNM Finding v6 and v7

description: Subglottic cancer with distant metastasis. (from AJCC 6th and 7th Eds.)


Colorectal Cancer pT3 TNM Finding v7

description: Colorectal cancer with invasion through the muscularis propria into pericolorectal tissues. (from AJCC 7th Ed.)


Neck Edema, CTCAE

description: A disorder characterized by swelling due to an accumulation of excessive fluid in the neck.


name: Soft Tissue Sarcoma of the Trunk and Extremities cM0 TNM Finding v8

description: Soft tissue sarcoma of the trunk and extremities without distant metastasis. (from AJCC 8th Ed.)


name: Grade 1 Depressed Level of Consciousness, CTCAE

description: Decreased level of alertness


PSA Level Less than Ten

description: A blood concentration of prostate specific antigen less than 10 ng/mL.


Autopsy TNM Finding

description: TNM staging performed on autopsy.


name: Malignant Neoplasm of Unspecified Site of Left Male Breast

description: Evidence of a malignant neoplasm of an unspecified site of left male breast.


Acute Respiratory Distress

description: An abrupt onset of signs or symptoms indicating difficulty breathing including alterations in breath sounds and rate, chest retractions and color changes.


Esophageal Obstruction, CTCAE

description: A disorder characterized by blockage of the normal flow of the contents in the esophagus.


Grade 3 Pleural Infection, CTCAE

description: IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated


name: Cocaine Abuse, Unspecified with Withdrawal

description: Evidence of cocaine abuse, unspecified with withdrawal.


name: Unspecified Sequelae of Cerebral Infarction

description: Evidence of unspecified sequelae of cerebral infarction.


description: An adenocarcinoma associated with the presence of human papillomavirus infection.


name: Non-Myocardial Visceral Arterial Ischemia, CTCAE


Kidney Cancer pMX TNM Finding v6

description: Kidney cancer in which distant metastasis cannot be assessed. (from AJCC 6th Ed.)


Refractory T-Cell and NK-Cell Neoplasm

description: T-cell and NK-cell neoplasm that is resistant to treatment.


name: Grade 4 Urinary Conduit Intra-Operative Injury, CTCAE


Grade 2 Wound Dehiscence, CTCAE

description: Incisional separation, local care (e.g., suturing) or medical intervention indicated (e.g., analgesic)


Grade 4 Neonatal Constipation, AE

description: A constipation adverse event in a newborn characterized by life-threatening consequences.


Eyelid Carcinoma pN2 TNM Finding v8

description: Eyelid carcinoma with metastasis in a single ipsilateral regional lymph node, measuring more than 3 cm in greatest dimension, or in bilateral or contralateral lymph nodes. (from AJCC 8th Ed.)


name: Uterine Corpus Leiomyosarcoma and Endometrial Stromal Sarcoma pT2b TNM Finding v8

description: Uterine corpus leiomyosarcoma or endometrial stromal sarcoma with tumor involving other pelvic tissues. (from AJCC 8th Ed.)


Recurrent Primary Cutaneous Lymphoma

description: The reemergence of primary cutaneous lymphoma after a period of remission.


Grade 4 Keratitis, CTCAE

description: Perforation; best corrected visual acuity of 20/200 or worse in the affected eye


name: Other Reactive Arthropathies, Right Knee

description: Evidence of other reactive arthropathies in the right knee not specified elsewhere.


name: Conjunctival Melanoma pNX TNM Finding v8

description: Conjunctival melanoma in which the regional lymph nodes cannot be assessed. (from AJCC 8th Ed.)


Grade 2 Guillain-Barre Syndrome, CTCAE

description: Moderate symptoms; limiting instrumental ADL