Grade 1 Neonatal Edema, AE

description: An adverse event in a newborn characterized by mild edema; no change in age appropriate behavior; no care changes indicated.


name: Nasal Cavity and Ethmoid Sinus Cancer pT4b TNM Finding v7

category: biolink:PhenotypicFeature biolink:DiseaseOrPhenotypicFeature biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing

description: Nasal cavity and ethmoid sinus cancer with very advanced local disease.  Tumor invades any of the following: orbital apex, dura, brain, middle cranial fossa, cranial nerves other than maxillary division of trigeminal nerve, nasopharynx, or clivus. (from AJCC 7th Ed.)


name: Skin Squamous Cell Carcinoma or Other Skin Carcinomas pN1 TNM Finding v7

description: Skin squamous cell carcinoma or other skin carcinomas with metastasis in a single ipsilateral lymph node, 3 cm or less in greatest dimension.  (from AJCC 7th Ed.)


name: Unspecified Juvenile Rheumatoid Arthritis, Other Specified Site

category: biolink:Disease biolink:DiseaseOrPhenotypicFeature biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing

description: Evidence of unspecified juvenile rheumatoid arthritis in an other specified site.


name: Grade 1 Intraoperative Reproductive Tract Injury, CTCAE

description: Primary repair of injured organ/structure indicated


Cutaneous Melanoma pT3 TNM Finding v8

description: Cutaneous melanoma measuring more than 2.0 and equal to or less than 4.0 mm in thickness. Ulceration status: Unknown or unspecified. (from AJCC 8th Ed.)


name: diabetes mellitus type 1 with hypoglycemia with coma

description: Evidence of type 1 diabetes mellitus with hypoglycemia with coma.


name: Atherosclerosis of Unspecified Type of Bypass Graft(s) of Right Leg with Ulceration of Unspecified Site

description: Evidence of atherosclerosis of unspecified type of bypass graft(s) of right leg with ulceration of unspecified site.


name: Small Intestine Cancer pN1 TNM Finding v7

description: Small intestine cancer with metastasis in 1-3 regional lymph nodes. (from AJCC 7th Ed.)


name: Grade 5 Neuroendocrine ACTH Deficiency, CTCAE


Decreased Enamel

description: Decrease in the amount of enamel.


Grade 3 Wound Dehiscence, CTCAE

description: Fascial disruption or dehiscence without evisceration; revision by operative intervention indicated


name: Grade 2 Neutrophils and Granulocytes, CTCAE


name: Grade 4 Bronchus Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


Defined Adverse Event

description: An adverse event that has a concise explanation of the meaning of term.


Recurrent Hematologic Malignancy

description: The reemergence of a hematologic malignancy after a period of remission.


name: Pre-Existing Secondary Hypertension Complicating Pregnancy, First Trimester

description: Evidence of pre-existing secondary hypertension complicating pregnancy in the first trimester.


Stage II Adult Hodgkin Lymphoma

description: Ann Arbor Classification: Stage II: Involvement of two or more lymph node regions on the same side of the diaphragm (II); or localized involvement of a single extralymphatic organ or site in association with regional lymph node involvement with or without involvement of other lymph node regions on the same side of the diaphragm (IIE).


Grade 4 Mucositis Oral, CTCAE

description: Life-threatening consequences; urgent intervention indicated


name: Grade 5 Injury, Poisoning and Procedural Complications - Other, Specify, CTCAE

description: Death


Seizure, CTCAE 5.0

description: A disorder characterized by a sudden, involuntary skeletal muscular contractions of cerebral or brain stem origin.


Hemoglobin Lepore Syndrome

description: A beta thalassemia resulting from an unequal crossover/recombination event involving portions of the delta and beta globin genes, resulting in underproduction of the abnormal delta-beta globin.


Cutaneous Melanoma pT3a TNM Finding v8

description: Cutaneous melanoma measuring more than 2.0 and equal to or less than 4.0 mm in thickness. Ulceration status: Without ulceration. (from AJCC 8th Ed.)


name: Major Salivary Gland Cancer cN2c TNM Finding V8

description: Major salivary gland cancer with metastasis in bilateral or contralateral lymph nodes, none larger than 6 cm in greatest dimension and ENE(-). (from AJCC 8th Ed.)


name: Rheumatoid Myopathy with Rheumatoid Arthritis of Right Wrist

description: Evidence of rheumatoid myopathy with rheumatoid arthritis of right wrist.


name: Unresectable Pancreatic Neuroendocrine Tumor

description: Pancreatic neuroendocrine tumor that is not amenable to surgical resection.


Other malignant mast cell neoplasm

description: Evidence of other malignant mast cell neoplasm not specified elsewhere.


Subglottic Cancer pT4b TNM Finding v8

description: Subglottic cancer with very advanced local disease. Tumor invades prevertebral space, encases carotid artery, or invades mediastinal structures. (from AJCC 8th Ed.)


name: Nasal Cavity and Ethmoid Sinus Cancer pT0 TNM Finding v6 and v7

description: Nasal cavity and ethmoid sinus cancer with no evidence of a primary tumor. (from AJCC 6th and 7th Eds.)


Grade 3 Ileal Obstruction, CTCAE

description: Hospitalization indicated; invasive intervention indicated; limiting self care ADL; long intestinal tube indicated


Lupus Flare

description: An exacerbation of the chronic disease lupus.


name: Grade 3 Pharynx Infection with Unknown Absolute Neutrophil Count, CTCAE


Palisaded encapsulated neuroma

description: A benign peripheral nerve sheath tumor characterized by the presence of Schwann cells, axons, and perineurial fibroblasts.  It usually arises from the skin of the head and neck or the oral mucosa.  It presents as a solitary and painless nodular mass.


Malignant neoplasm of myometrium

description: Evidence of a malignant neoplasm of the myometrium.


Papilledema, CTCAE

description: A disorder characterized by swelling around the optic disc.


Refractory Meningioma

description: Meningioma that is resistant to treatment.


Anal Cancer TNM Finding v7

description: A finding about one or more characteristics of anal cancer, following the rules of the TNM AJCC v7 classification system.  This classification applies to carcinomas arising in the anal canal only; melanomas, carcinoid tumors, sarcomas, and perianal tumors are not included. (from AJCC 7th Ed.)


name: Mental and Behavioral Signs and Symptoms

description: Clinical evidence of disease resulting from mental and/or behavioral dysfunction.


Staphylococcal enterocolitis

description: Gastroenteritis resulting from an infection with Staphylococcus aureus.


name: Small Bowel NOS Intra-Operative Injury, CTCAE


name: Hypopharyngeal Cancer pM1 TNM Finding v8

description: Hypopharyngeal cancer with distant metastasis. (from AJCC 8th Ed.)


name: Grade 3 Eye Infection NOS with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


Retinoblastoma cT4c TNM Finding v7

description: Intracranial extension not past chiasm. (from AJCC 7th Ed.)


name: Hypopharyngeal Cancer pT4a TNM Finding V6

description: Hypopharyngeal cancer with tumor invading thyroid/cricoid cartilage, hyoid bone, thyroid gland, esophagus or central compartment soft tissue. (from AJCC 6ht Ed.)


Advanced Carcinoma

description: Carcinoma that has spread extensively to other anatomic sites or is no longer responding to treatment.


name: Grade 3 Heart Infection with Unknown Absolute Neutrophil Count, CTCAE


name: Grade 4 Vein Infection with Unknown Absolute Neutrophil Count, CTCAE


Stage II Cervical Cancer AJCC v9

description: Stage II includes: T2, N0, M0. T2: Tumor invading beyond the uterus but not to the pelvic wall or to lower third of vagina. N0: No regional lymph node metastasis. M0: No distant metastasis. (from AJCC 9th Ed.)


name: PSA Nadir Greater than or Equal to 0.5 ng/mL

description: A finding indicating that the lowest blood concentration of prostate specific antigen for a subject was greater than or equal to 0.5 ng/mL.


Cholecystitis, CTCAE 5.0

description: A disorder characterized by inflammation involving the gallbladder. It may be associated with the presence of gallstones.


Retinoblastoma cT1b TNM Finding v7

description: At least one tumor is greater than 3 mm in largest dimension or located closer than 1.5 mm to the optic nerve or fovea.  No retinal detachment or subretinal fluid beyond 5 mm from the base of the tumor. (from AJCC 7th Ed.)


inhalant dependence - uncomplicated

description: Evidence of inhalant dependence, uncomplicated.


name: Gallbladder Cancer Pathologic Regional Lymph Nodes TNM Finding v8

description: A pathologic finding about one or more characteristics of gallbladder cancer, following the rules of the TNM AJCC v8 classification system as they pertain to staging of regional lymph nodes.


name: Grade 4 Upper Gastrointestinal Hemorrhage, CTCAE

description: Life-threatening consequences; urgent intervention indicated


name: Grade 3 Cranial Nerve I Neuropathy, CTCAE


name: Other Acute Monocytic Leukemia not Having Achieved Remission

description: Evidence of other acute monocytic leukemia not having achieved remission not specified elsewhere.


name: Pathologic Stage IIIC Cutaneous Melanoma AJCC v8

description: Stage IIIC includes: (T0, N2b, N2c, N3b or N3c); (T1a-T3a, N2c or N3a/b/c, M0); (T3b/T4a, Any N greater than or equal to N1, M0); (T4b, N1a-N2c, M0). T0: No evidence of primary tumor (e.g., unknown primary or completely regressed melanoma). Thickness: Not applicable. Ulceration status: Not applicable. T1a: Tumor measuring less than 0.8 mm in thickness. Ulceration status: Without ulceration. T1b: Tumor measuring less than 0.8 mm in thickness with ulceration, or 0.8-1.0 mm with or without ulceration. T2a: Tumor measuring more than 1.0 and equal to or less than 2.0 mm in thickness. Ulceration status: Without ulceration. T2b: Tumor measuring more than 1.0 and equal to or less than 2.0 mm in thickness. Ulceration status: With ulceration. T3a: Tumor measuring more than 2.0 and equal to or less than 4.0 mm in thickness. Ulceration status: Without ulceration. T3b: Tumor measuring more than 2.0 and equal to or less than 4.0 mm in thickness. Ulceration status: With ulceration. T4a: Tumor measuring more than 4.0 mm in thickness. Ulceration status: Without ulceration. T4b: Tumor measuring more than 4.0 mm in thickness. Ulceration status: With ulceration.  N2b: Two or three nodal metastases at least one of which was clinically detected. Presence of in-transit, satellite, and/or microsatellite metastases: No. N2c: One clinically occult nodal metastasis. Presence of in-transit, satellite, and/or microsatellite metastases: Yes. N3b: Four or more nodal metastases, at least one of which was clinically detected, or presence of any number of matted nodes. Presence of in-transit, satellite, and/or microsatellite metastases: No. N3c: Two or more clinically occult nodal metastases. Presence of in-transit, satellite, and/or microsatellite metastases: Yes. N3a: Four or more clinically occult nodal metastasis (i.e., detected by sentinel lymph node biopsy). Presence of in-transit, satellite, and/or microsatellite metastases: No. N1a: One clinically occult nodal metastasis (i.e., detected by sentinel lymph node biopsy). Presence of in-transit, satellite, and/or microsatellite metastases: No. N1b: One clinically detected nodal metastasis. Presence of in-transit, satellite, and/or microsatellite metastases: No. N1c: No regional lymph node disease. Presence of in-transit, satellite, and/or microsatellite metastases: Yes. N2a: Two or three clinically occult nodal metastases (i.e., detected by sentinel lymph node biopsy). Presence of in-transit, satellite, and/or microsatellite metastases: No. M0: No evidence of distant metastasis. LDH level is not applicable. (AJCC 8th ed.)


Partial Response with Lymphocytosis

description: A decrease in the size and extent of tissue involvement by cancer, accompanied by an increase in blood lymphocyte count above a predetermined threshold.


name: Merkel Cell Carcinoma cN0 TNM Finding v8

description: Merkel cell carcinoma without regional lymph node metastasis detected on clinical and/or radiologic examination. (from AJCC 8th Ed.)


name: Nasal Cavity and Paranasal Sinuses Cancer cN1 TNM Finding v8

description: Nasal cavity and paranasal sinuses cancer with metastasis in a single ipsilateral lymph node, 3 cm or smaller in greatest dimension and ENE(-). (from AJCC 8th Ed.)


name: Grade 3 Inner Ear Intra-Operative Injury, CTCAE


Grade 4 Neonatal Epileptic Seizure, AE

description: An adverse event in a newborn characterized by electroencephalogram (EEG)- proven seizures with life-threatening consequences (e.g. need for ventilation); status epilepticus (greater than 30 minutes of seizure activity within any 60 minute period) despite multiple anti-seizure drugs.


Concentration Impairment, CTCAE

description: A disorder characterized by a deterioration in the ability to concentrate.


name: Digestive System Neuroendocrine Tumor TNM Finding v8

description: A finding about one or more characteristics of a digestive system neuroendocrine tumor, following the rules of the TNM AJCC v8 classification system.


name: Localized Non-Muscle Invasive Bladder Urothelial Carcinoma

description: A bladder urothelial carcinoma that is confined to the site in which it initially manifested without evidence of spread to other anatomic sites, and has not invaded the bladder muscularis propria.


name: Maxillary Sinus Cancer pT4b TNM Finding v6

description: Maxillary sinus cancer with tumor invading any of the following: orbital apex, dura, brain, middle cranial fossa, cranial nerves other than maxillary division of trigeminal nerve, nasopharynx, or clivus. (from AJCC 6th Ed.)


Partial Volume Averaging Between Slices

description: An artifact that happens when a structure is present in adjacent slices and their signals are averaged.


name: Grade 3 Colon or Cecum or Appendix Fistula, CTCAE


Epilepsy aggravated

description: An increase in the duration or intensity of epileptic symptoms in the setting of chronic epilepsy.


name: Epithelioid Hemangioendothelioma with YAP1-TFE3 Gene Fusion

description: Epithelioid hemangioendothelioma characterized by a YAP1-TFE3 gene fusion. This gene fusion occurs in a subset of epithelioid hemangioendotheliomas characterized by the presence of well-formed vessels lined by epithelioid endothelial cells with abundant eosinophilic cytoplasm. Patients with YAP1-TFE3 gene fusion tumors tend to be younger than those with a WWTR1-CAMTA1 gene fusion.


name: Neoantigen-Positive Malignant Solid Neoplasm

description: A malignant solid neoplasm characterized by the expression of antigens resulting from cancer-specific mutations (neoantigens).


name: Other Paralytic Syndrome following Other Non-Traumatic Intracranial Hemorrhage Affecting Right Dominant Side

description: Evidence of other paralytic syndrome following other non-traumatic intracranial hemorrhage affecting right dominant side not specified elsewhere.


name: Unspecified Malignant Neoplasm of Skin of Nose

description: Evidence of unspecified malignant neoplasm of the skin of the nose.


Recurrence of Primary in Prostate

description: A recurrence of disease at the site of the primary prostatic lesion.


Mature Glial Implant

description: A nodule of mature glial tissue that develops in the peritoneum. It is usually accompanied by mature or immature ovarian teratoma.


name: Drug or Chemical Induced Diabetes Mellitus with Severe Non-Proliferative Diabetic Retinopathy without Macular Edema

description: Evidence of drug or chemical induced diabetes mellitus with severe non-proliferative diabetic retinopathy without macular edema.


Capillary Leak Syndrome, CTCAE

description: A disorder characterized by leakage of intravascular fluids into the extravascular space. This syndrome is observed in patients who demonstrate a state of generalized leaky capillaries following shock syndromes, low-flow states, ischemia-reperfusion injuries, toxemias, medications, or poisoning. It can lead to generalized edema and multiple organ failure.


name: Grade 3 Visceral Arterial Ischemia, CTCAE

description: Prolonged (>=24 hrs) or recurring symptoms and/or invasive intervention indicated


Peripheral Sensory Neuropathy, CTCAE

description: A disorder characterized by damage or dysfunction of the peripheral sensory nerves.


Grade 2 Personality Change, CTCAE

description: Moderate personality change


name: Lugano Classification Stage IIE Adult Hodgkin Lymphoma AJCC v8

description: Stage IIE: Contiguous extralymphatic extension from a nodal site with or without involvement of other lymph node regions on the same side of the diaphragm. (from AJCC 8th Ed.)


name: Drug or Chemical Induced Diabetes Mellitus with Moderate Non-Proliferative Diabetic Retinopathy with Macular Edema

description: Evidence of drug or chemical induced diabetes mellitus with moderate non-proliferative diabetic retinopathy with macular edema.


Cerebellar Ataxia, Late Onset

description: Evidence of late-onset cerebellar ataxia.


name: Femoral Hernia with Obstruction without Mention of Gangrene

description: The protrusion of contents of the abdominal cavity, into the femoral canal, which results in obstruction of intestinal peristalsis, with no mention of necrosis of the herniated contents.


name: Grade 2 Esophagus Stricture or Stenosis, CTCAE


name: Postoperative Thoracic Procedure Complication, CTCAE

description: A finding of a previously undocumented problem that occurs after a thoracic procedure.


name: Grade 2 Trachea Mucositis or Stomatitis by Functional or Symptomatic Classification, CTCAE


Body Mass Index 45.0-49.9, Adult

description: Evidence of a body mass index of 45.0-49.9 in the adult.


name: Grade 2 Pancreatic Enzymes Decreased, CTCAE

description: Increase in stool frequency, bulk, or odor; steatorrhea


Vaginal Inflammation, CTCAE

description: A disorder characterized by inflammation involving the vagina. Symptoms may include redness, edema, marked discomfort and an increase in vaginal discharge.


Burning Wood Smoke Exposure

description: Environmental or occupational exposure to airborne gases and particulates produced when wood is subjected to combustion.


Refractory Ependymoma

description: Ependymoma that does not respond to treatment.


name: Renal Pelvis and Ureter Cancer pT2 TNM Finding v8

description: Renal pelvis and ureter cancer in which the tumor invades the muscularis. (from AJCC 8th Ed.)


name: Direct Infection of Vertebrae in Infectious and Parasitic Diseases Classified Elsewhere

description: Evidence of direct infection of vertebrae in infectious and parasitic diseases classified elsewhere.


name: Nasopharyngeal Cancer Pathologic Distant Metastasis TNM Finding v8

description: A pathologic finding about one or more characteristics of nasopharyngeal cancer, following the rules of the TNM AJCC v8 classification system as they pertain to distant metastases.


Bodily Pain

description: The sensation of acute or chronic suffering in a body region.


Stage II Osteosarcoma AJCC v7

description: Stage II includes: IIA (T1, N0, M0, G3, G4); IIB (T2, N0, M0, G3, G4).  T1: Tumor 8 cm or less in greatest dimension.  T2: Tumor more than 8 cm in greatest dimension.  N0: No regional lymph node metastasis.  M0: No distant metastasis.  G3: Poorly differentiated.  G4: Undifferentiated. (AJCC 7th ed.)


Sézary's disease of spleen

description: Evidence of Sezary disease in the spleen.


name: Relapse Following Intervention for Kawasaki Disease

description: An indication that there was a relapse following treatment for Kawasaki disease.


name: Metastatic Malignant Neoplasm in the Genitourinary System

description: The spread of a malignant neoplasm to the genitourinary system from an adjacent or distant anatomic site.


name: Malignant Neoplasm of Upper-Inner Quadrant of Left Male Breast

description: Evidence of a malignant neoplasm of the upper-inner quadrant of left male breast.


Grade 3 Testicular Disorder, CTCAE

description: Severe symptoms; interfering with sexual function; limiting self care ADL; intervention indicated


name: Type 1 Diabetes Mellitus with Proliferative Diabetic Retinopathy with Traction Retinal Detachment not Involving the Macula, Right Eye

description: Evidence of type 1 diabetes mellitus with proliferative diabetic retinopathy with traction retinal detachment not involving the macula in the right eye.


name: CRP Level Greater than or Equal to 3 mg/L

description: A laboratory test result indicating that C-reactive protein is present in a sample at concentrations of 3 mg/L or more.


name: Conjunctival Melanoma cT3a TNM Finding v8

description: Conjunctival melanoma with tumor of any size invading the globe. (from AJCC 8th Ed.)


name: Other Reactive Arthropathies, Left Shoulder

description: Evidence of other reactive arthropathies in the left shoulder not specified elsewhere.


Papulopustular Rash, CTCAE

description: A disorder characterized by an eruption consisting of papules (a small, raised pimple) and pustules (a small pus filled blister), typically appearing in face, scalp, and upper chest and back. Unlike acne, this rash does not present with whiteheads or blackheads, and can be symptomatic, with itchy or tender lesions.


name: Other Malignant Neoplasm Skin of Left Lower Limb, Including Hip

description: Evidence of other malignant neoplasm skin of the left lower limb including the hip not specified elsewhere.


Grade 1 Non-Cardiac Chest Pain, CTCAE

description: Mild pain


name: Grade 2 Blood Infection with Unknown Absolute Neutrophil Count, CTCAE


Lip Pain, CTCAE 5.0

description: A disorder characterized by a sensation of marked discomfort of the lip.


name: Atherosclerosis of Non-Autologous Biological Bypass Graft(s) of the Extremities with Rest Pain, Left Leg

description: Evidence of atherosclerosis of non-autologous biological bypass graft(s) of the extremities with rest pain in the left leg.


name: Other Rheumatoid Arthritis with Rheumatoid Factor of Unspecified Wrist

description: Evidence of other rheumatoid arthritis with rheumatoid factor of unspecified wrist not specified elsewhere.


name: Anaplastic Large Cell Lymphoma, ALK-Negative, Lymph Nodes of Inguinal Region and Lower Limb

description: Evidence of anaplastic large cell lymphoma that is ALK-Negative in the lymph nodes of inguinal region and lower limb.


Disruptive mood dysregulation disorder

description: A condition in which children or adolescents experience irritability, anger, and intense temper outbursts. The episodes may be frequent and may eventually impact functioning at school, at home or with peers.


Mild Cardiac Valve Regurgitation

description: Evidence of mild retrograde blood flow through the valve(s) of the heart. (ACC)


name: Narcolepsy in Conditions Classified Elsewhere without Cataplexy

description: Evidence of narcolepsy in conditions classified elsewhere without cataplexy.


Domestic Accident

description: An accident taking place within a home.


name: Benign Mixed Epithelial and Mesenchymal Hair Follicle Neoplasm

description: A trichoblastoma characterized by the presence of neoplastic epithelial cells forming cribriform patterns.


Grade 4 Joint Infection, CTCAE

description: Life-threatening consequences; urgent intervention indicated


name: Heart Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


name: Grade 1 Neuroendocrine ADH Secretion Abnormality, CTCAE


name: Overlapping malignant neoplasm of biliary tract

description: Evidence of a malignant neoplasm of overlapping sites of the biliary tract.


name: Grade 3 Intraoperative Renal Injury, CTCAE

description: Complete resection or reconstruction of injured organ/structure indicated; limiting self care ADL


name: Grade 2 Pancreas Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


Stage IV Vulvar Cancer AJCC v7

description: Stage IV includes: IVA: (T1/T2, N3, M0); (T3, Any N, M0); IVB: (Any T, Any N, M1).  T1: Invasive vulvar cancer confined to the vulva or perineum.  T2: Vulvar cancer with tumor of any size with extension to adjacent perineal structures (lower/distal 1/3 urethra, lower/distal 1/3 vagina, anal involvement).  T3: Vulvar cancer with tumor of any size with extension to any of the following: upper/proximal 2/3 urethra, upper/proximal 2/3 vagina, bladder mucosa, rectal mucosa, or fixed to pelvic bone.  N3: Vulvar cancer with fixed or ulcerated regional lymph node metastasis.  M1: distant metastasis (including pelvic lymph node metastasis).  (AJCC 7th ed.)


name: Uterine Corpus Leiomyosarcoma and Endometrial Stromal Sarcoma TNM Finding v8

description: A finding about one or more characteristics of uterine corpus leiomyosarcoma or endometrial stromal sarcoma, following the rules of the TNM AJCC v8 classification system.


name: Nasal Cavity and Paranasal Sinuses Cancer pNX TNM Finding v8

description: Nasal cavity and paranasal sinuses cancer in which the regional lymph nodes cannot be assessed. (from AJCC 8th Ed.)


name: Mediastinal Germ Cell Tumor M1 TNM Finding

description: Mediastinal germ cell tumor with distant metastasis. (WHO Classification of Tumors of the Lung, Pleura, Thymus and Heart, 2015)


name: Grade 5 Voice Changes and Dysarthria, CTCAE


name: Stage IV Anal Canal Cancer AJCC v6 and v7

description: Stage IV includes: (Any T, Any N, M1).  M1: Distant metastasis. (AJCC 6th and 7th Eds.)


Grade 2 Prostatic Pain, CTCAE

description: Moderate pain; limiting instrumental ADL


Central Nervous System Necrosis, CTCAE

description: A disorder characterized by a necrotic process occurring in the brain and/or spinal cord.


name: Lip and Oral Cavity Cancer pNX TNM Finding v8

description: Lip and oral cavity cancer in which the regional lymph nodes cannot be assessed. (from AJCC 8th Ed.)


name: Ampulla of Vater Cancer Pathologic Distant Metastasis TNM Finding v8

description: A pathologic finding about one or more characteristics of ampulla of Vater cancer, following the rules of the TNM AJCC v8 classification system as they pertain to distant metastases.


name: Hepatocellular Carcinoma Clinical TNM Finding v8

description: A clinical finding about one or more characteristics of hepatocellular carcinoma, following the rules of the TNM AJCC v8 classification system.


name: Parathyroid Carcinoma pT1 TNM Finding v8

description: Tumor localized to the parathyroid gland with extension limited to soft tissue. (from AJCC 8th Ed.)


name: Soft Tissue Sarcoma of the Abdomen and Thoracic Visceral Organs pN0 TNM Finding v8

description: Soft tissue sarcoma of the abdomen and thoracic visceral organs without lymph node involvement or unknown lymph node status. (from AJCC 8th Ed.)


FGFR Family Alteration Negative

description: An indication that mutation, overexpression, fusion or rearrangement of an FGFR family member has not been detected in a sample.


name: Grade 5 Prolapse of Intestinal Stoma, CTCAE

description: Death


name: Lung Cancer Pathologic Regional Lymph Nodes TNM Finding v6

description: A pathologic finding about one or more characteristics of lung cancer, following the rules of the TNM AJCC v6 classification system as they pertain to staging of regional lymph nodes.


Other childhood disintegrative disorder

description: Evidence of other childhood disintegrative disorder not specified elsewhere.


Transient Ischemic Attacks, CTCAE

description: A disorder characterized by a brief attack (less than 24 hours) of cerebral dysfunction of vascular origin, with no persistent neurological deficit.


Glottic Cancer pT4 TNM Finding v8

description: Glottic cancer with moderately advanced or very advanced disease. (from AJCC 8th Ed.)


Retinoblastoma pN0 TNM Finding v8

description: Retinoblastoma with no lymph node involvement. (from AJCC 8th Ed.)


name: Radiating Chest Pain Along Left Upper Sternal Border

description: The location of the radiating chest pain is along the left upper sternal border.


name: Distal Bile Duct Cancer pN2 TNM Finding v8

description: Distal bile duct cancer with metastasis in four or more regional lymph nodes. (from AJCC 8th Ed.)


name: Acute Myeloid Leukemia with t(3;8)(q26.2;q24); MYC, MECOM

description: An acute myeloid leukemia associated with t(3;8)(q26.2;q24) resulting in MYC and MECOM rearrangement.


name: Urethral Cancer Pathologic Primary Tumor TNM Finding v7

description: A pathologic finding about one or more characteristics of urethral cancer, following the rules of the TNM AJCC v7 classification system as they pertain to staging of the primary tumor.


Grade 1 Laryngeal Hemorrhage, CTCAE

description: Mild cough or trace hemoptysis; laryngoscopic findings


name: Hematologic Neoplasm with Germline Predisposition without a Constitutional Disorder Affecting Multiple Organ Systems

description: Familial hematologic neoplasms associated with germline mutations without a preexisting disorder or organ dysfunction.


name: Grade 2 Soft Tissue NOS Intra-Operative Injury, CTCAE


name: Prostate Cancer Pathologic Regional Lymph Nodes TNM Finding v8

description: A pathologic finding about one or more characteristics of prostate cancer, following the rules of the TNM AJCC v8 classification system as they pertain to staging of regional lymph nodes.


name: Malignant neoplasm of other parts of pancreas

description: Evidence of a malignant neoplasm of other parts of pancreas.


name: Ocular Adnexal Lymphoma pTX TNM Finding v8

description: Lymphoma extent not specified. (from AJCC 8th Ed.)


Grade 4 Gastric Anastomotic Leak, CTCAE

description: Life-threatening consequences; urgent operative intervention indicated


name: Drug or Chemical Induced Diabetes Mellitus with Severe Non-Proliferative Diabetic Retinopathy without Macular Edema, Bilateral

description: Evidence of drug or chemical induced diabetes mellitus with severe non-proliferative diabetic retinopathy without macular edema that is bilateral.


name: Grade 2 Soft Tissue Infection NOS Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


Chronic pulmonary aspergillosis

description: A spectrum of disorders associated with long-term Aspergillus infection of the lung that usually occur in immunocompetent individuals with underlying respiratory disorders, and may be characterized by pulmonary fibrosis or cavitation.


Testicular Cancer pT4 TNM Finding v8

description: Testicular cancer in which the tumor invades scrotum with or without lymphovascular invasion. (from AJCC 8th Ed.)


name: Advanced Extrapulmonary Small Cell Neuroendocrine Carcinoma

description: Extrapulmonary small cell neuroendocrine carcinoma that has spread extensively to other anatomic sites or is no longer responding to treatment.


Middle Ear Inflammation, CTCAE

description: A disorder characterized by inflammation (physiologic response to irritation), swelling and redness to the middle ear.


name: Unresectable Digestive System Adenocarcinoma

description: An adenocarcinoma that arises from the gastrointestinal system and is not amenable to surgical resection.


Acquired kyphosis

description: Kyphosis, the cause of which is not present at birth.


Hepatic Necrosis, CTCAE 5.0

description: A disorder characterized by a necrotic process occurring in the hepatic parenchyma.


name: Hypopharyngeal Cancer Pathologic Distant Metastasis TNM Finding v8

description: A pathologic finding about one or more characteristics of hypopharyngeal cancer, following the rules of the TNM AJCC v8 classification system as they pertain to distant metastases.


name: Arthropathy following Intestinal Bypass, Left Knee

description: Evidence of arthropathy following intestinal bypass in the left knee.


Cardiovascular Radiation Injury

description: Radiation injury of the cardiovascular system.


Grade 3 Pulmonary Valve Disease, CTCAE

description: Symptomatic; severe regurgitation or stenosis by imaging; symptoms controlled with medical intervention


name: COVID-19-Associated Nervous System Disorder

description: A central or peripheral nervous system disorder caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).


Lower Abdominal Pain

description: A sensation of discomfort emanating from the inferior quadrants of the abdomen, which may be peritoneal or visceral in origin, or referred from an extra-abdominal location.


Radiolucent Lines

description: An xray finding that indicates a void or area of tissue that is less dense. Radiolucent lines can be prognostic factors after surgical joint replacements.


Insufficient RNA Yield

description: An indication that an RNA isolation procedure yielded an insufficient amount of RNA to proceed.


name: Merkel Cell Carcinoma pN2 TNM Finding v7

description: Merkel cell carcinoma with in transit metastasis.  In transit metastasis is defined as a tumor distinct from the primary lesion and located either (1) between the primary lesion and the draining regional lymph nodes or (2) distal to the primary lesion. (from AJCC 7th Ed.)


name: Coronary Artery Ectasia Related to COVID-19

description: Coronary artery ectasia in a patient with probable or confirmed acute COVID-19.


Reiter's Disease, Left Ankle and Foot

description: Evidence of Reiter's disease in the left ankle and foot.


name: Grade 2 Urinary Conduit Intra-Operative Injury, CTCAE


Testicular Cancer pN2 TNM Finding v7

description: Metastasis with a lymph node mass more than 2 cm but not more than 5 cm in greatest dimension; or more than five nodes positive, none more than 5 cm; or evidence of extranodal extension of tumor. (from AJCC 7th Ed.)


name: hallucinogen abuse with intoxication - uncomplicated

description: Evidence of hallucinogen abuse with intoxication, uncomplicated.


Grade 3 Non-Cardiac Chest Pain, CTCAE

description: Severe pain; limiting self care ADL


Childhood Pleomorphic Xanthoastrocytoma

description: A pleomorphic xanthoastrocytoma that occurs during childhood.


name: Oropharyngeal (p16-Negative) Cancer pN2b TNM Finding v8

description: Oropharyngeal (p16-negative) cancer with metastases in multiple ipsilateral lymph nodes, none larger than 6 cm in greatest dimension and ENE(-). (from AJCC 8th Ed.)


Jaccoud Arthropathy, Multiple Sites

description: Evidence of Jaccoud arthropathy, multiple sites.


Glucosuria, CTCAE

description: A disorder characterized by laboratory test results that indicate glucose in the urine.


Grade 2 Enterocolitis, CTCAE

description: Abdominal pain; mucus or blood in stool


name: Soft Tissue Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils NOS, CTCAE


Grade 3 Vital Capacity Abnormal, CTCAE

description: <50% of predicted value; limiting self care ADL


name: Grade 5 Recurrent Laryngeal Nerve Palsy, CTCAE

description: Death


Bleeding on Probing

description: Bleeding that is induced by gentle manipulation of the gingival tissue at the depth of the gingival sulcus.


name: Duodenum/Ampulla/Jejunum/Ileum Neuroendocrine Tumor Pathologic Primary Tumor TNM Finding v7

description: A pathologic finding about one or more characteristics of duodenum/ampulla/jejunum/ileum neuroendocrine tumor, following the rules of the TNM AJCC v7 classification system as they pertain to staging of the primary tumor.


Stage III Esophageal Cancer AJCC v7

description: Stage III includes: For squamous cell carcinoma: IIIA (T1-2, N2, M0, Any G, Tumor location: Any); (T3, N1, M0, Any G, Tumor location: Any); (T4a, N0, M0, Any G, Tumor location: Any); IIIB (T3, N2, M0, Any G, Tumor location: Any); IIIC (T4a, N1-2, M0, Any G, Tumor location: Any); (T4b, Any N, M0, Any G, Tumor location: Any); (Any T, N3, M0, Any G, Tumor location: Any).  For adenocarcinoma: IIIA (T1-2, N2, M0, Any G); (T3, N1, M0, Any G); (T4a, N0, M0, Any G); IIIB (T3, N2, M0, Any G); IIIC (T4a, N1-2, M0, Any G); (T4b, Any N, M0, Any G); (Any T, N3, M0, Any G).  T1: Tumor invades lamina propria, muscularis mucosae, or submucosa.  T2: Tumor invades muscularis propria. T3: Tumor invades adventitia. T4a: Resectable tumor invading pleura, pericardium, or diaphragm. T4b: Unresectable tumor invading other adjacent structures, such as aorta, vertebral body, trachea, etc. N0: No regional lymph node metastasis.  N1: Metastasis in 1-2 regional lymph nodes.  N2: Metastasis in 3-6 regional lymph nodes.  N3: Metastasis in seven or more regional lymph nodes.  M0: No distant metastasis.  Tumor location: Location of the primary cancer site is defined by the position of the upper (proximal) edge of the tumor in the esophagus.  (AJCC 7th ed.)


name: Mediastinal Germ Cell Tumor N0 TNM Finding

description: Mediastinal germ cell tumor with no regional lymph node metastasis. (WHO Classification of Tumors of the Lung, Pleura, Thymus and Heart, 2015)


Epididymal Papillary Cystadenoma

description: A cystadenoma that arises from the epididymis. It is characterized by the presence of small papillary projections in the inner surface of the cysts. It may be sporadic or associated with von Hippel-Lindau disease.


Advanced Basal Cell Carcinoma

description: Basal cell carcinoma that has spread extensively to other anatomic sites or is no longer responding to treatment.


Stage IIB Bone Sarcoma AJCC v7

description: Stage IIB includes: T2, N0, M0, G3, G4.  T2: Tumor more than 8 cm in greatest dimension.  N0: No regional lymph node metastasis.  M0: No distant metastasis.  G3: Poorly differentiated.  G4: Undifferentiated. (AJCC 7th ed.)


name: Grade 3 Ophthalmoplegia and Diplopia, CTCAE


name: Grade 1 Cranial Nerve III Intra-Operative Injury, CTCAE


name: Grade 3 Persistent Pulmonary Hypertension of the Newborn, AE

description: An adverse event in a newborn characterized by Increased estimated right ventricular pressures; with severe clinical symptoms; oxygenation index greater than 25; major care changes required (e.g. inhaled nitric oxide (iNO)).


name: Grade 4 Small Bowel Infection NOS Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


name: Grade 5 Urethral Anastomotic Leak, CTCAE

description: Death


name: Rheumatoid Arthritis with Rheumatoid Factor of Right Knee without Organ or Systems Involvement

description: Evidence of rheumatoid arthritis with rheumatoid factor of right knee without organ or systems involvement.


name: Perihilar Bile Duct Cancer pT4 TNM Finding v8

description: Perihilar bile duct cancer with tumor invading the main portal vein or its branches bilaterally, or the common hepatic artery; or unilateral second-order biliary radicals with contralateral portal vein or hepatic artery involvement. (from AJCC 8th Ed.)


name: Rheumatoid Vasculitis with Rheumatoid Arthritis of Left Knee

description: Evidence of rheumatoid vasculitis with rheumatoid arthritis of left knee.


name: Grade 2 Uterus Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


Field Burning Smoke Exposure

description: Environmental or occupational exposure to airborne gases and particulates produced when trees, brush and grass in a field are burning.


Disease regression

description: Return to a former state; a subsidence of the symptoms of a disease process; in cancer, a decrease in the size of a tumor or in the extent of cancer in the body.


name: Grade 4 Peritoneal Cavity Hemorrhage, CTCAE


name: Pathologic Stage IIA Cutaneous Melanoma AJCC v8

description: Stage IIA includes: (T2b, N0, M0); (T3a, N0, M0). T2b: Tumor measuring more than 1.0 and equal to or less than 2.0 mm in thickness. Ulceration status: With ulceration. T3a: Tumor measuring more than 2.0 and equal to or less than 4.0 mm in thickness. Ulceration status: Without ulceration. N0: No regional lymph node metastasis detected. Presence of in-transit, satellite, and/or microsatellite metastases: No. M0: No evidence of distant metastasis. LDH level is not applicable. (AJCC 8th ed.)


name: Grade 5 Large Bowel Mucositis or Stomatitis by Clinical Examination Classification, CTCAE


name: Atherosclerosis of Non-Biological Bypass Graft(s) of the Extremities with Gangrene, Unspecified Extremity

description: Evidence of atherosclerosis of non-biological bypass graft(s) of the extremities with gangrene, unspecified extremity.


Acquired Phrenic Nerve Palsy

description: Damage to the phrenic nerve that results in paralysis of the hemidiaphragm and was not present at birth.


Normal Abdomen on Visual Inspection

description: An indication that there are no abnormal findings on visual inspection of the abdomen.


name: Grade 3 Genitourinary Stoma Hemorrhage, CTCAE


name: Grade 5 Intraoperative Endocrine Injury, CTCAE

description: Death


name: Subglottic Cancer pTis TNM Finding v6 and v7

description: Subglottic cancer with a finding of carcinoma in situ. (from AJCC 6th and 7th Eds.)


name: Circumscribed Meningeal Melanocytic Neoplasm

description: A circumscribed neoplasm that arises from leptomeningeal melanocytes. This category includes meningeal melanocytoma and meningeal melanoma.


Mycosis fungoides (Working Formulation)

description: A peripheral (mature) T-cell lymphoma presenting in the skin with patches/plaques and it is characterized by epidermal and dermal infiltration of small to medium-sized T-cells with cerebriform nuclei.  Patients with limited disease generally have an excellent prognosis.  In the more advanced stages, the prognosis is poor. (WHO, 2001)


name: Unspecified Juvenile Rheumatoid Arthritis, Unspecified Knee

description: Evidence of unspecified juvenile rheumatoid arthritis in an unspecified knee.


name: Gastric ulcer, unspecified as acute or chronic, without hemorrhage or perforation

description: Evidence of gastric ulcer, unspecified as acute or chronic, without hemorrhage or perforation.


name: Vascular dementia with behavioral disturbance

description: Evidence of vascular dementia with behavioral disturbance.


First degree uterine prolapse

description: The uterus has descended above the hymen.


name: Merkel Cell Carcinoma Pathologic Regional Lymph Nodes TNM Finding v8

description: A pathologic finding about one or more characteristics of Merkel cell carcinoma, following the rules of the TNM AJCC v8 classification system as they pertain to staging of regional lymph nodes.


name: central retinal artery occlusion of right eye

description: Evidence of central retinal artery occlusion in the right eye.


Stage III Uterine Corpus Cancer AJCC v6

description: Stage III includes: III (T3, N0, M0); IIIA (T3a, N0, M0); IIIB (T3b, N0, M0); IIIC (T1, N1, M0); (T2, N1, M0); (T3, N1, M0).  T3: Local and/or regional spread as defined below.  T3a: Tumor invades serosa and/or adnexa (direct extension or metastasis) and/or cancer cells in ascites or peritoneal washings.  T3b Vaginal involvement (direct extension or metastasis). N0: No regional lymph node metastasis. N1: Regional lymph node metastasis to pelvic and/or para-aortic nodes.  M0: No distant metastasis. (AJCC 6th ed.)


name: Stage M1 Childhood Ependymoma by Toronto Guidelines v2

description: Tumor cells in the CSF. (Childhood cancer staging for population registries according to the Toronto Childhood Cancer Stage Guidelines - Version 2. Cancer Council Queensland and Cancer Australia: Brisbane, Australia; 2021.)


name: Human Papillomavirus-Independent Vaginal Squamous Cell Carcinoma

description: Vaginal squamous cell carcinoma not associated with human papillomavirus infection.


Stage IIA Cervical Cancer AJCC v9

description: Stage IIA includes: T2a, N0, M0. T2a: Tumor with involvement limited to the upper two-thirds of the vagina without parametrial invasion. N0: No regional lymph node metastasis. M0: No distant metastasis. (from AJCC 9th Ed.)


Post-streptococcal reactive arthritis

description: The occurrence of arthritis after infection with group A streptococcus. It is non-migratory, protracted in course, and poorly responsive to anti-inflammatory agents. (from Textbook of Pediatric Rheumatology, 6th ed. Cassidy, Petty, Laxer, and Lindsley)


name: Refractory Female Reproductive System Carcinoma

description: Female reproductive system carcinoma that is resistant to treatment.


name: Other Specified Diabetes Mellitus with Proliferative Diabetic Retinopathy with Traction Retinal Detachment not Involving the Macula, Right Eye

description: Evidence of other specified diabetes mellitus with proliferative diabetic retinopathy with traction retinal detachment not involving the macula in the right eye not specified elsewhere.


name: Merkel Cell Carcinoma of Left Upper Limb, Including Shoulder

description: Evidence of Merkel cell carcinoma of left upper limb including the shoulder.


name: Mycosis Fungoides and Sezary Syndrome N1b TNM Finding v7

description: Clone positive.  Note: A T-cell clone is defined by PCR or Southern blot analysis of the T-cell receptor gene.  (from AJCC 7th Ed.)


Homicide by Assault

description: Death of an individual by physical violence from another.


Exercise Tolerance Test Result

description: The result of an evaluation of an individual's ability to endure the workload that is achieved during a specified period of exercise.


Cutaneous Melanoma cM1b TNM Finding v8

description: Cutaneous melanoma with distant metastasis to lung with or without M1a sites of disease. LDH level not recorded or unspecified. (from AJCC 8th Ed.)


name: Low Grade Corneal Squamous Intraepithelial Neoplasia

description: A precancerous neoplastic intraepithelial process with low-grade dysplastic features involving the corneal epithelium.


name: Intraductal papillary neoplasm with high grade intraepithelial neoplasia

description: An intraductal papillary neoplasm that arises from the epithelium of the intrahepatic or extrahepatic bile ducts. It is characterized by the presence of severe epithelial atypia.


name: Grade 4 Tendon Intra-Operative Injury, CTCAE


name: Cerebral Infarction due to Unspecified Occlusion or Stenosis of Right Vertebral Artery

description: Evidence of cerebral infarction due to an unspecified occlusion or stenosis of the right vertebral artery.


Nuclear Cataract Grade 3

description: A stage of nuclear sclerotic cataract marked by pronounced yellowing and sclerosis of the lens nucleus. (Modified LOCS II)


name: Grade 2 Gastrointestinal Stoma Intra-Operative Injury, CTCAE


name: Malignant neoplasm overlapping lip, oral cavity and pharynx sites

description: Evidence of a malignant neoplasm of overlapping sites of the lip, oral cavity and pharynx.


Alcoholic Gastritis without Bleeding

description: Evidence of alcoholic gastritis without bleeding.


name: Grade 2 Irritability in Children Less Than 3 Years of Age, CTCAE


Sentinel Lymph Node Not Identified

description: An indication that sentinel lymph node mapping was attempted but that it did not identify a sentinel lymph node.


name: Grade 5 Upper Extremity Soft Tissue Necrosis Adverse Event, CTCAE


name: Platinum-Sensitive Fallopian Tube Carcinoma

description: Fallopian tube carcinoma that has a documented response to platinum-based chemotherapy.


Grade 4 Hearing Impaired, CTCAE

description: Adults: Decrease in hearing to profound bilateral loss (absolute threshold >80 dB HL at 2 kHz and above); nonservicable hearingPediatric: Audiologic indication for cochlear implant; > 40 dB HL (i.e., 45 dB HL or more); SNHL at 2 kHz and above


name: Nodular Lymphocyte Predominant Hodgkin Lymphoma, Extranodal and Solid Organ Site

description: Evidence of nodular lymphocyte predominant Hodgkin lymphoma in the extranodal and solid organ site.


Gastric mucositis

description: An inflammatory process affecting the mucous membrane of the stomach.


Function Result Measurement

description: A result of a function test.


Hypoxia, CTCAE

description: A disorder characterized by a decrease in the level of oxygen in the body.


name: Grade 1 Cranial Nerve IX Neuropathy, CTCAE


name: Stage IVA Cervical Cancer AJCC v6 and v7

description: Stage IVA includes: T4, Any N, M0). T4: Tumor invades mucosa of bladder or rectum, and/or extends beyond true pelvis (bullous edema is not sufficient to classify a tumor as T4). M0: No distant metastasis. (AJCC 6th and 7th eds.)


Benign neoplasm of lacrimal apparatus

description: A neoplasm that arises from the lacrimal gland or lacrimal drainage system and is characterized by the absence of atypical or malignant cytological and architectural features, and absence of invasive features or metastatic potential.


name: Mycosis Fungoides and Sezary Syndrome Lymph Nodes TNM Finding v7

description: A finding about one or more characteristics of mycosis fungoides and Sezary syndrome, following the rules of the TNM AJCC v7 classification system as they pertain to staging of peripheral lymph nodes.


name: FIGO Stage IIC Gestational Trophoblastic Tumor


Normal Karyotype

description: The assessment of the karyotype is that it is normal.


Grade 2 Ventricular Tachycardia, CTCAE

description: Non-urgent medical intervention indicated


Carcinoma in situ of exocervix

description: Evidence of carcinoma in situ of the exocervix.


Grade 1 Hearing Impaired, CTCAE

description: Adults enrolled on a Monitoring Program (on a 1, 2, 4, 3, 6, and 8 kHz audiogram): Threshold shift of 15-25 dB averaged at 2 contiguous test frequencies in at least one ear; Adults not enrolled on a Monitoring Program: Subjective change in hearing in the absence of documented hearing loss; Pediatric (on a 1, 2, 3, 4, 6, and 8 kHz audiogram): Threshold shift >20 dB hearing loss (HL) (i.e., 25 dB HL or greater); sensorineural hearing loss (SNHL) above 4 kHz (i.e., 6 or 8 kHz) in at least one ear


name: Pleural Mesothelioma Pathologic Distant Metastasis TNM Finding v7

description: A pathologic finding about one or more characteristics of pleural mesothelioma, following the rules of the TNM AJCC v7 classification system as they pertain to distant metastases.  There is no pathologic M0 for pleural mesothelioma.


Hyalinizing Clear Cell Carcinoma

description: A rare, slow-growing carcinoma characterized by the presence of malignant clear and eosinophilic cells in a hyalinized stroma. It has been described in the salivary glands and lung. Most cases are associated with translocation of EWSR1 and ATF1, resulting in the formation of EWSR1-ATF1 fusion gene. The prognosis is good.


Lumbar myelocele

description: Herniation of spinal cord tissue and meninges through a defect in the lumbar region of the vertebral column. The protrusion of the tissue is flush with the level of the skin surface.


name: Metastatic Bladder Clear Cell (Glycogen-Rich) Urothelial Carcinoma

description: Bladder clear cell (glycogen-rich) urothelial carcinoma that has spread to another anatomic site.


Grade 4 Intracranial Hemorrhage, CTCAE

description: Life-threatening consequences; urgent intervention indicated


Tumor Pain, CTCAE 5.0

description: A disorder characterized by a sensation of marked discomfort from a neoplasm that may be pressing on a nerve, blocking blood vessels, inflamed or fractured from metastasis.


name: Other Specified Rheumatoid Arthritis, Unspecified Wrist

description: Evidence of other specified rheumatoid arthritis in an unspecified wrist not specified elsewhere.


name: Juvenile Rheumatoid Arthritis with Systemic Onset, Left Wrist

description: Evidence of juvenile rheumatoid arthritis with systemic onset in the left wrist.


Malignant Neoplasm of Left Upper Limb

description: Evidence of a malignant neoplasm of the left upper limb.


name: Malignant immunoproliferative disease (clinical)

description: Evidence of a malignant immunoproliferative disease.


Cutaneous Melanoma pN2a TNM Finding v8

description: Cutaneous melanoma with two or three clinically occult nodal metastases (i.e., detected by sentinel lymph node biopsy). Presence of in-transit, satellite, and/or microsatellite metastases: No.  (from AJCC 8th Ed.)


name: Grade 2 Non-Malignant Pleural Effusion, CTCAE


name: Grade 2 Conjunctiva Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


name: Distal Bile Duct Cancer cM0 TNM Finding v7

description: Distal bile duct cancer without evidence of distant metastasis. (from AJCC 7th Ed.)


name: Myelodysplastic Syndrome, Unclassifiable, with Defining Cytogenetic Abnormality

description: Myelodysplastic syndrome, unclassifiable characterized by persistent cytopenia (s) with 1 percent or fewer blasts in the blood and fewer than 5% in the bone marrow, unequivocal dysplasia in less than 10 percent of the cells in one or more myeloid lineages, and cytogenetic abnormalities considered as presumptive evidence of myelodysplastic syndrome.


name: Distal Bile Duct Cancer pN0 TNM Finding v8

description: Distal bile duct cancer with no metastasis to regional lymph nodes. (from AJCC 8th Ed.)


Achromic nevus

description: A benign nevus characterized by the absence of melanin pigment in the melanocytes.


Papillary neoplasm

description: A benign, intermediate, or malignant neoplasm characterized by the formation of papillary structures.


name: Grade 4 Uterus Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


name: Rheumatoid Arthritis of Left Hip with Involvement of Organs and Systems

description: Evidence of rheumatoid arthritis of left hip with involvement of organs and systems.


name: Childhood Langerhans Cell Histiocytosis without Risk Organ Involvement

description: Langerhans cell histiocytosis that occurs during childhood and does not involve the bone marrow, spleen, liver, or lung.


Grade 2 Hyperphosphatemia, CTCAE

description: Noninvasive intervention indicated


Esophageal adenocarcinoma stage IV

description: An adenocarcinoma that arises from the esophagus and has metastasized to another anatomic site.


Destructive Arthritis

description: Arthritis associated with the destruction of the cartilage and the articular surface of the bone of the joint. This process severely interferes with movement in the joint.


Grade 2 Laryngospasm, CTCAE

description: Transient episode; intervention not indicated


Lymphoma by Ann Arbor Stage

description: An anatomic stage for Hodgkin and non-Hodgkin lymphomas  based on the Ann Arbor classification criteria.


Breast Cancer pN1 TNM Finding v8

description: Breast cancer with micrometastases; or metastases in 1-3 axillary lymph nodes; and/or clinically negative internal mammary nodes with micrometastases or macrometastases by sentinel lymph node biopsy. (from AJCC 8th Ed.)


name: Lower Extremity Vein Intra-Operative Injury, CTCAE


Bilateral glaucoma

description: Increased pressure in both eyeballs due to obstruction of the outflow of aqueous humor.


T2a1 TNM Finding

description: A general term that refers to a TNM finding of a primary tumor with direct invasion of adjacent structures. The definition of T2a1 TNM finding depends on the specific type of cancer to which it refers: for example, for cervical carcinoma it indicates involvement limited to the upper two-thirds of the vagina without parametrial invasion measuring 4.0 cm or less in greatest dimension.


name: Maxillary Sinus Cancer cM1 TNM Finding v7

description: Maxillary sinus cancer with distant metastasis. (from AJCC 7th Ed.)


name: Follicular Lymphoma Grade IIIb, Intrapelvic Lymph Nodes

description: Evidence of follicular lymphoma grade IIIb in the intrapelvic lymph nodes.


name: Chest Pain Along Left Midclavicular Line

description: The location of the chest pain is along the left midclavicular line.


name: Unknown Primary Tumor cN3 TNM Finding v8

description: Unknown primary tumor with metastasis in a cervical lymph node larger than 6 cm in greatest dimension and ENE(-); or metastasis in any cervical node(s) with clinically overt ENE(+) (ENEc). ENEc is defined as invasion of skin, infiltration of musculature, dense tethering or fixation to adjacent structures, or cranial nerve, brachial plexus, sympathetic trunk, or phrenic nerve invasion with dysfunction. (from AJCC 8th Ed.)


Recurrent Childhood Malignant Neoplasm

description: The reemergence of a childhood malignant neoplasm after a period of remission.


name: Grade 4 Aspartate Aminotransferase Increased, CTCAE

description: >20.0 x ULN if baseline was normal; >20.0 x baseline if baseline was abnormal


Chief Complaint Occurs at Rest

description: The chief complaint typically occurs at rest.


name: Grade 1 Recurrent Laryngeal Nerve Palsy, CTCAE

description: Asymptomatic; clinical or diagnostic observations only; intervention not indicated


name: Locally Advanced Malignant Female Reproductive System Neoplasm

description: A malignant female reproductive system neoplasm that has spread from its original site of growth to nearby tissues or lymph nodes.


name: Other Specified Diabetes Mellitus with Hypoglycemia with Coma

description: Evidence of other specified diabetes mellitus with hypoglycemia with coma not specified elsewhere.


name: Hypopharyngeal Cancer Clinical Regional Lymph Nodes TNM Finding v8

description: A clinical finding about one or more characteristics of hypopharyngeal cancer, following the rules of the TNM AJCC v8 classification system as they pertain to staging of regional lymph nodes.


name: Unspecified Juvenile Rheumatoid Arthritis, Left Wrist

description: Evidence of unspecified juvenile rheumatoid arthritis in the left wrist.


name: Zaidi Recurrence Risk Score Greater than or Equal to 6

description: A score of greater than or equal to 6 using the Zaidi criteria for recurrence risk for resected pancreatic neuroendocrine tumors. This score correlates with high risk of recurrence.


Free Testosterone Less than 70 pg/mL

description: A semiquantitative finding indicating that the concentration of free testosterone in a sample is less than 70 pg/mL.


name: Grade 3 Intraoperative Reproductive Tract Injury, CTCAE

description: Complete resection or reconstruction of injured organ/structure indicated; limiting self care ADL


Intercalated Duct Hyperplasia

description: A salivary ductal proliferation resembling intercalated ducts. (WHO 2017)


Childhood Diabetes Mellitus

description: Diabetes mellitus that develops during childhood.


name: Grade 3 Vein NOS Intra-Operative Injury, CTCAE


Grade 2 Pancreatic Hemorrhage, CTCAE

description: Moderate symptoms; intervention indicated


name: Pre-Existing Type 2 Diabetes Mellitus, Type 2, in Pregnancy, Unspecified Trimester

description: Evidence of pre-existing type 2 diabetes mellitus in the type 2 in the in pregnancy in an unspecified trimester.


name: Precursor T-lymphoblastic lymphoma/leukemia recurrent

description: The reemergence of T-lymphoblastic leukemia/lymphoma after a period of remission.


Pseudotumor of Kidney

description: A parenchymal lesion, which may appear neoplastic in origin, that results from abnormal architecture of the renal calyx.


Vaginal Undifferentiated Carcinoma

description: A carcinoma that arises from the vagina and is characterized by the lack of specific cellular differentiation.


name: Gastrointestinal Neuroendocrine Tumor TNM Finding v7

description: A finding about one or more characteristics of gastrointestinal neuroendocrine tumor, following the rules of the TNM AJCC v7 classification system.  This classification applies to gastric, small bowel, colonic, rectal, and ampulla of Vater carcinoid tumors; carcinoid tumors of the appendix and neuroendocrine tumors of the pancreas are not included in this classification. (from AJCC 7th Ed.)


name: Neuroendocrine Gonadotropin Secretion Abnormality, CTCAE


LYRIC Indeterminate Response

description: A lymphoma response that cannot be distinguished between flare/pseudo-progression and true progressive disease.


name: DYSKERATOSIS CONGENITA, AUTOSOMAL RECESSIVE 5

description: Dyskeratosis congenita caused by mutation(s) in the RTEL1 gene, encoding regulator of telomere elongation helicase 1.


name: Musculoskeletal Chest Pain due to Costochondritis

description: A condition in which there is musculoskeletal chest pain associated with inflammation of one or more ribs and/or cartilages. (ACC/AHA)


Breast Cancer cM1 TNM Finding v8

description: Breast cancer with distant metastases detected by clinical and radiographic means and/or histologically proven metastases larger than 0.2 mm. (from AJCC 8th Ed.)


name: Ampulla of Vater Cancer pNX TNM Finding v8

description: Ampulla of Vater cancer in which the regional lymph nodes cannot be assessed.  (from AJCC 8th Ed.)


name: Stage III Gestational Trophoblastic Neoplasm AJCC v8

description: Stage III includes: Any T, M1a. M1a: Gestational trophoblastic neoplasm with lung metastasis. (AJCC 8th Ed.)


Grade 2 Platelet Count Decreased, CTCAE

description: <75,000-50,000/mm3; <75.0-50.0 x 10e9/L


Cervical Cancer pT4 TNM Finding v8

description: Cervical cancer invading the mucosa of the bladder or rectum, and/or extending beyond the true pelvis (bullous edema is not sufficient to classify a tumor as T4). (from AJCC 8th Ed.)


name: Chronic Post-Rheumatic Arthropathy, Left Ankle and Foot

description: Evidence of chronic post-rheumatic arthropathy in the left ankle and foot.


name: Pathologic Stage IV Esophageal Adenocarcinoma AJCC v8

description: Stage IV includes: IVA: (T4a, N2, M0, Any G); (T4b, N0-2, M0, Any G); (Any T, N3, M0, Any G); IVB: (Any T, Any N, M1, Any G). T4a: Tumor invades the pleura, pericardium, azygos vein, diaphragm, or peritoneum. T4b: Tumor invades other adjacent structures, such as the aorta, vertebral body, or airway. N0: No regional lymph node metastasis. N1: Tumor with metastasis in one or two regional lymph nodes. N2: Tumor with metastasis in three to six regional lymph nodes. N3: Tumor with metastasis in seven or more regional lymph nodes. M0: No distant metastasis. M1: Distant metastasis. (AJCC 8th ed.)


name: Cutaneous Mature T-Cell and NK-Cell Neoplasm

description: A group of neoplasms composed of T-lymphocytes with a mature (peripheral/post-thymic) immunophenotypic profile and/or NK-cells affecting the skin.


name: Cerebral Infarction due to Embolism of Left Carotid Artery

description: Evidence of cerebral infarction due to an embolism of the left carotid artery.


Colorectal Cancer pN0 TNM Finding v8

description: Colorectal cancer with no metastasis to regional lymph nodes. (from AJCC 8th Ed.)


Refractory Adenocarcinoma

description: An adenocarcinoma that does not respond to treatment.


EBV-Related Hodgkin Lymphoma

description: Hodgkin lymphoma that is caused by Epstein-Barr virus infection.


name: Grade 2 Extraocular Muscle Paresis, CTCAE

description: Unilateral paresis without double vision


name: High Grade Pancreatic Intraepithelial Neoplasia

description: A pancreatic epithelial neoplasia characterized by the presence of papillary and rarely flat architectural patterns with formation of cribriform patterns and luminal necrosis.  Severe dysplasia is present.


Grade 1 Urinary Tract Pain, CTCAE

description: Mild pain


name: Juvenile Arthritis, Unspecified, Unspecified Hip

description: Evidence of unspecified juvenile arthritis in the hip.


name: Gastric Neuroendocrine Tumor pNX TNM Finding v7

description: Gastric neuroendocrine tumor in which regional lymph nodes cannot be assessed. (from AJCC 7th Ed.)


Intraoperative Hemorrhage, CTCAE

description: A finding of uncontrolled bleeding during a surgical procedure.


Grade 2 Sore Throat, CTCAE

description: Moderate pain; limiting instrumental ADL


name: Grade 1 Outer Ear NOS Intra-Operative Injury, CTCAE


Neonatal Respiratory Insufficiency, AE

description: An adverse event in a newborn characterized by significant impairment of gas exchange resulting in compensatory breathing efforts and eventually hypoxia and/or hypercarbia. Note: Consider this adverse event for any patient whose respiratory condition deteriorates from baseline. If any specific diagnosis is identified: use diagnosis-specific scale (e.g. respiratory distress syndrome (RDS), pulmonary hemorrhage).


Ileal Ulcer, CTCAE

description: A disorder characterized by a circumscribed, erosive lesion on the mucosal surface of the ileum.


Neuroendocrine carcinoma of appendix

description: An aggressive, high-grade, and poorly differentiated carcinoma with neuroendocrine differentiation that arises from the appendix. The mitotic count is more than 20 per 10 HPF. It is classified as either small or large cell neuroendocrine carcinoma based on the size of the malignant cells, the prominence of the nucleoli, and the amount of cytoplasm.


name: Grade 2 Brain Intra-Operative Injury, CTCAE


Negative Lymph Node

description: A clinical finding that a lymph node is free from cancer spread.


Cervical Cancer cT2 TNM Finding v8

description: Cervical carcinoma invading beyond the uterus but not to the pelvic wall or to lower third of vagina. (from AJCC 8th Ed.)


MYC Negative

description: An indication that MYC expression has not been detected in a sample.


Grade 4 Stroke, CTCAE

description: Life-threatening consequences; urgent intervention indicated


name: Mycosis Fungoides and Sezary Syndrome B1b TNM Finding v7

description: Clone positive.  Note: A T-cell clone is defined by PCR or Southern blot analysis of the T-cell receptor gene.  (from AJCC 7th Ed.)


Hindgut Neuroendocrine Tumor G3

description: A neuroendocrine tumor grade 3 that arises from the sigmoid colon, descending colon, or rectum.


Grade 1 Colonic Hemorrhage, CTCAE

description: Mild symptoms; intervention not indicated


name: Locally Advanced Neuroendocrine Carcinoma

description: A neuroendocrine carcinoma that has spread from its original site of growth to nearby tissues or lymph nodes.


Grade 2 Gallbladder Infection, CTCAE

description: Oral intervention indicated (e.g., antibiotic, antifungal, or antiviral)


Other Symptom

description: A symptom that is not among those previously noted.


name: Carcinoma in Situ of Other Parts of Intestine

description: Evidence of carcinoma in situ of other parts of intestine.


Adrenal Insufficiency, CTCAE

description: A disorder characterized by the adrenal cortex not producing enough of the hormone cortisol and in some cases, the hormone aldosterone. It may be due to a disorder of the adrenal cortex as in Addison's disease or primary adrenal insufficiency.


name: Uterine Corpus Adenosarcoma pN1 TNM Finding v8

description: Uterine corpus adenosarcoma with regional lymph node metastasis. (from AJCC 8th Ed.)


name: Mycosis Fungoides and Sezary Syndrome TNM Finding v8

description: A finding about one or more characteristics of mycosis fungoides and Sezary syndrome, following the rules of the TNM AJCC v8 classification system. This classification is based on the ISCL/EORTC revision to the classification of mycosis fungoides and Sezary syndrome. (from AJCC 8th Ed.)


Pleural Mesothelioma pNX TNM Finding v7

description: Pleural mesothelioma in which regional lymph nodes cannot be assessed. (from AJCC 7th Ed.)


name: Gestational Trophoblastic Neoplasm cM0 TNM Finding v8

description: Gestational trophoblastic neoplasm without evidence of distant metastasis. (from AJCC 8th Ed.)


Grade 3 Ileus, CTCAE

description: Severely altered GI function; TPN indicated; tube placement indicated


name: Grade 4 Disseminated Intravascular Coagulation, CTCAE


Remote Placental Infarction

description: A focus of necrotic placental parenchyma with marked hyalinization and fibrosis with complete absence of the necrotic chorionic villi, which is frequently more than 7 days of duration.


name: Pathologic Stage IIA Esophageal Adenocarcinoma AJCC v8

description: Stage IIA includes: (T2, N0, M0, G3); (T2, N0, M0, GX). T2: Tumor invades the muscularis propria. N0: No regional lymph node metastasis. M0: No distant metastasis. GX: Grade cannot be assessed. G3: Poorly differentiated, undifferentiated. (AJCC 8th ed.)


name: Social Circumstances - Other, Specify, CTCAE


Stage IIIB Bladder Cancer AJCC v8

description: Stage IIIB includes: T1-T4a, N2, N3, M0. T1: Tumor invades lamina propria (subepithelial connective tissue). T2: Tumor invades muscularis propria. T3: Tumor invades perivesical soft tissue. T4a: Extravesical tumor invades directly into prostatic stroma, uterus, vagina. N2: Multiple regional lymph node metastasis in the true pelvis (perivesical, obturator, internal and external iliac, or sacral lymph node metastasis). N3: Lymph node metastasis to the common iliac lymph nodes. M0: No distant metastasis. (AJCC 8th ed.)


name: Grade 2 Spine Kyphosis or Lordosis, CTCAE


name: Grade 3 Allergic Reaction and Hypersensitivity Including Drug Fever, CTCAE


Acquired methemoglobinemia

description: Methemoglobinemia that is caused by exposure to certain drugs (xylocaine and benzene) and nitrate-rich foods.


Normal Carotid Arteriogram

description: An x-ray of the carotid arteries that reveals normal results.


Stage I Fallopian Tube Cancer AJCC v8

description: Stage I includes: T1, N0, M0. T1: Fallopian tube cancer with tumor limited to fallopian tube(s). N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 8th Ed.)


name: Grade 5 Lung Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


Cervical Cancer pT3 TNM Finding v8

description: Cervical cancer extending to pelvic sidewall and/or involving the lower third of vagina, and/or causing hydronephrosis or nonfunctioning kidney. The pelvic sidewall is defined as the muscle, fascia, neurovascular structures, and skeletal portions of the bony pelvis. (from AJCC 8th Ed.)


Stage I Vulvar Cancer AJCC v8

description: Stage I includes: T1, N0, M0. T1: Tumor confined to the vulva and/or perineum. Multifocal lesions should be designated as such. The largest lesion or the lesion with the greatest depth of invasion will be the target lesion identified to address the highest pT stage. Depth of invasion is defined as the measurement of the tumor from the epithelial-stromal junction of the adjacent most superficial dermal papilla to the deepest point of invasion. N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 8th Ed.)


name: Prolapse of Gastrointestinal Stoma, CTCAE


name: Rheumatoid Arthritis of Unspecified Shoulder with Involvement of Organs and Systems

description: Evidence of rheumatoid arthritis of unspecified shoulder with involvement of organs and systems.


pN0 (i+) TNM Finding

description: A regional lymph node TNM finding indicating that there are malignant cells in regional lymph node(s) no greater than 0.2 mm and are detected by hematoxylin and eosin stain or immunohistochemistry.


name: Ovarian, Fallopian Tube, and Primary Peritoneal Carcinoma pN0(i+) TNM Finding v8

description: Ovarian, fallopian tube, or primary peritoneal carcinoma with isolated tumor cells in regional lymph node(s) no greater than 0.2 mm. (from AJCC 8th Ed.)


Stage IV Bladder Cancer AJCC v8

description: Stage IV includes: IVA: (T4b, N0, M0); (Any T, Any N, M1a); IVB: (Any T, Any N, M1b). T4b: Extravesical tumor invades pelvic wall, abdominal wall. N0: No regional lymph node metastasis. M0: No distant metastasis. M1a: Distant metastasis limited to lymph nodes beyond the common iliacs. M1b: Non-lymph node distant metastases. (AJCC 8th ed.)


Grade 1 Irritability, CTCAE

description: Mild; easily consolable


Sharp Pain

description: A sensation of discomfort or distress that is distinct and intensely focused.


Diffusion Restriction

description: A radiologic finding seen as high-signal intensity on diffusion weighted imaging with corresponding reduced apparent diffusion coefficient (ADC) values. ADC is a measurement of the diffusion of water molecules in a given tissue.


Grade 3 Spasticity, CTCAE

description: Severe increase in muscle tone and increase in resistance through range of motion


name: Helicobacter Pylori-Related Gastric Adenocarcinoma

description: An adenocarcinoma that arises from the gastric mucosa and is caused by persistent infection with Helicobacter pylori.


name: Type 1 Diabetes Mellitus with Severe Nonproliferative Diabetic Retinopathy with Macular Edema, Left Eye

description: Evidence of type 1 diabetes mellitus with severe nonproliferative diabetic retinopathy with macular edema in the left eye.


name: Malignant neoplasm of connective and soft tissue of trunk, unspecified

description: Evidence of a malignant neoplasm of connective and soft tissue of trunk.


name: Arthropathy following Intestinal Bypass, Unspecified Hip

description: Evidence of arthropathy following intestinal bypass in an unspecified hip.


name: Locally Advanced Transitional Cell Carcinoma

description: Transitional cell carcinoma that has spread from its original site of growth to nearby tissues or lymph nodes.


Grade 3 Gastrointestinal Fistula, CTCAE

description: Invasive intervention indicated


name: Grade 4 Supraventricular Tachycardia, CTCAE

description: Life-threatening consequences


Unifocal Lesion

description: A lesion arising from or having a single location.


Grade 3 Laryngitis, CTCAE

description: IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated


description: Evidence of opioid dependence with opioid-induced psychotic disorder with hallucinations.


Anal Cancer cM1 TNM Finding v7

description: Anal cancer with distant metastasis. (from AJCC 7th Ed.)


Performed Medical History Result

description: The case history of a subject.


Grade 3 Neonatal Convulsion, AE

description: An adverse event in a newborn characterized by suspected seizures uncontrolled with one anti-seizure drug (recurrence within three days after treatment or requiring two or more anti-seizure drugs).


name: Severe recurrent major depression without psychotic features

description: Evidence of major depressive disorder, recurrent severe without psychotic features.


name: Grade 1 Lower Gastrointestinal Hemorrhage, CTCAE

description: Mild symptoms; intervention not indicated


Grade 3 Gastric Hemorrhage, CTCAE

description: Transfusion indicated; invasive intervention indicated; hospitalization


name: Soft Tissue Sarcoma of the Abdomen and Thoracic Visceral Organs pT4b TNM Finding v8

description: Soft tissue sarcoma of the abdomen and thoracic visceral organs with multifocal involvement (three to five sites). (from AJCC 8th Ed.)


name: Maxillary Sinus Cancer Pathologic Distant Metastasis TNM Finding v6

description: A pathologic finding about one or more characteristics of maxillary sinus cancer, following the rules of the TNM AJCC v6 classification system as they pertain to distant metastases.


Melanoma in situ of anal skin

description: Evidence of melanoma in situ of anal skin.


name: Merkel cell carcinoma of right lower eyelid, including canthus

description: Evidence of Merkel cell carcinoma of right lower eyelid including the canthus.


name: Grade 4 Skin Infection with Unknown Absolute Neutrophil Count, CTCAE


Chemical esophagitis

description: Esophagitis secondary to chemical exposure.


name: Endocrine disorder arising from mental factors

description: An endocrine disorder that is caused by abnormal mental function.


name: Grade 5 Heart Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


Very Good Partial Response

description: Partial response with additional serum and urine M-protein reduction, but not meeting complete response.


Vessel Or Plaque, Device Embedded In

description: Device and/or fragments of device are embedded in patient's vessel and/or plaque.


Recurrent Childhood Oligodendroglioma

description: The reemergence of oligodendroglioma in childhood after a period of remission.


Grade 4 Personality Change, CTCAE

description: Life-threatening consequences, threats of harm to self or others; hospitalization indicated


name: Diabetes Mellitus due to Underlying Condition with Severe Non-Proliferative Diabetic Retinopathy without Macular Edema, Bilateral

description: Evidence of diabetes mellitus due to underlying condition with severe non-proliferative diabetic retinopathy without macular edema that is bilateral.


name: Brachial Plexus Intra-Operative Injury, CTCAE


Cervical Cancer pT1 TNM Finding v8

description: Cervical carcinoma confined to uterus (extension to corpus should be disregarded). (from AJCC 8th Ed.)


Graft, Prosthesis, or Flap Failure

description: A failure of function of a graft, flap, or prosthesis.


name: Jejunum and Ileum Neuroendocrine Tumor pT0 TNM Finding v8

description: Jejunum and ileum neuroendocrine tumor with no evidence of primary tumor. (from AJCC 8th Ed.)


name: Grade 4 Reversible Posterior Leukoencephalopathy Syndrome, CTCAE

description: Life-threatening consequences


Glucose Intolerance, CTCAE

description: A disorder characterized by an inability to properly metabolize glucose.


Testosterone Greater than 75 ng/dL

description: A semiquantitative finding indicating that the concentration of testosterone in a sample is greater than 75 ng/dL.


Familial Testicular Germ Cell Tumor

description: Germ cell tumor that arises from the testis and is diagnosed in at least two relatives.


Lung Cancer pM1a TNM Finding v7

description: Lung cancer with separate tumor nodule(s) in a contralateral lobe; tumor with pleural nodules or malignant pleural (or pericardial) effusion.  Most pleural (and pericardial) effusions with lung cancer are due to tumor.  In a few patients, however, multiple cytopathologic examinations of pleural (or pericardial) fluid) are negative for tumor, and the fluid is nonbloody and is not an exudate.  Where these elements and clinical judgment dictate that the effusion is not related to the tumor, the effusion should be excluded as a staging element and the patient should be classified as M0. (from AJCC 7th Ed.)


MCPyV Negative

description: An indication that Merkel cell polyomavirus has not been detected in a sample.


Grade 2 Colitis, CTCAE

description: Abdominal pain; mucus or blood in stool


name: Mucosal Melanoma of the Head and Neck pT4 TNM Finding v8

description: Mucosal melanoma of the head and neck with moderately advanced or very advanced disease. (from AJCC 8th Ed.)


name: Grade 2 Neck Infection NOS with Unknown Absolute Neutrophil Count, CTCAE


name: Rheumatoid Lung Disease with Rheumatoid Arthritis of Left Hip

description: Evidence of rheumatoid lung disease with rheumatoid arthritis of left hip.


Ileal Obstruction, CTCAE

description: A disorder characterized by blockage of the normal flow of the intestinal contents in the ileum.


Floaters, CTCAE

description: A disorder characterized by an individual seeing spots before their eyes. The spots are shadows of opaque cell fragments in the vitreous humor or lens.


name: Stage II Adult Diffuse Small Cleaved Cell Lymphoma

description: Stage II: Involvement of two or more lymph node regions on the same side of the diaphragm (II) or localized involvement of a single associated extralymphatic organ or site and its regional lymph nodes with or without other lymph node regions on the same side of the diaphragm (IIE). Note: The number of lymph node regions involved may be indicated by a subscript (e.g., II3). (from PDQ)


Congenital hamartoma

description: A hamartomatous lesion which is present at birth.


name: Cutaneous Melanoma Pathologic Primary Tumor TNM Finding v7

description: A pathologic finding about one or more characteristics of cutaneous melanoma, following the rules of the TNM AJCC v7 classification system as they pertain to staging of the primary tumor.  The TNM pathologic and clinical primary tumor classifications of cutaneous melanoma are the same. (from AJCC 7th Ed.)


name: Other Epilepsy, Intractable, with Status Epilepticus

description: Evidence of other epilepsy, with status epilepticus that does not respond optimally to treatment not specified elsewhere.


Immune System and Related Disorders

description: A group of non-neoplastic and neoplastic disorders resulting from the deregulation and/or deficiency of immune system functions. It includes autoimmune disorders (e.g., lupus erythematosus, dermatomyositis, rheumatoid arthritis), congenital and acquired immunodeficiency syndromes including the acquired immune deficiency syndrome (AIDS), and neoplasms (e.g., lymphomas and malignancies secondary to transplantation).


name: Hypopharyngeal Cancer cN1 TNM Finding v8

description: Hypopharyngeal cancer with metastasis in a single ipsilateral lymph node, 3 cm or smaller in greatest dimension and ENE (-). (from AJCC 8th Ed.)


Grade 5 Hyperphosphatemia, CTCAE

description: Death


Cervical Cancer cT2a1 TNM Finding v7

description: Cervical cancer invades beyond uterus but not to pelvic wall or to lower third of vagina.  There is no parametrial invasion.  Clinically visible lesions 4.0 cm or less in greatest dimension are present.  (from AJCC 7th Ed.)


Inappropriate Manual Collimation

description: An image of reduced quality resulting from the application of a mask in the wrong way.


name: Metastatic malignant neoplasm to right adrenal gland

description: Evidence of secondary malignant neoplasm of right adrenal gland.


Grade 1 Bile Duct Stenosis, CTCAE

description: Asymptomatic; clinical or diagnostic observations only; intervention not indicated


name: Cervical Adenocarcinoma Admixed with Neuroendocrine Carcinoma

description: A carcinoma that arises from the cervix and is characterized by the presence of a cervical adenocarcinoma variant and a neuroendocrine carcinoma component.


Phrenic Nerve Palsy Related to Birth

description: A condition characterized by reduced or absent movement of the ipsilateral diaphragm as a consequence of an injury to the phrenic nerve or its origin in cervical roots 3 through 5 sustained during the birthing process.


name: Diabetes Mellitus due to Underlying Condition with Other Diabetic Neurological Complication

description: Evidence of diabetes mellitus due to underlying condition with other diabetic neurological complication.


name: Conjunctival Melanoma pT2a TNM Finding v8

description: Conjunctival melanoma with tumor of the nonbulbar conjunctiva with invasion of the substantia propria, not more than 2.0 mm in thickness. (from AJCC 8th Ed.)


name: Carotid Artery Intra-Operative Injury, CTCAE


name: Metastatic Malignant Neoplasm in the Visual Pathway

description: A malignant neoplasm that has spread to the visual pathway from another anatomic site.


Grade 2 Hydrocephalus, CTCAE

description: Moderate symptoms; intervention not indicated


name: Grade 4 Somnolence and Depressed Level of Consciousness, CTCAE


name: Grade 2 Vein Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


Advanced Ampulla of Vater Carcinoma

description: Carcinoma that arises from the ampulla of Vater and has spread extensively to other anatomic sites or is no longer responding to treatment.


Stage IVA Bladder Cancer

description: Stage IV includes T4b, NO,MO/any T NI, MO/ any T N2 MO,/ any T N3 MO/ any T any N M1 : T4b: Tumor invades the pelvic wall, abdominal wall. N1: Metastasis in a single lymph node, 2 cm or less in greatest dimension. N2: Metastasis in a single lymph node, more than 2 cm but not more than 5 cm in greatest dimension; or multiple lymph nodes, none more than 5 cm in greatest dimension. N3: Metastasis in a lymph node more than 5 cm in greatest dimension. M1: Distant metastasis.


name: Moderately Differentiated Malignant Neoplasm

description: A neoplasm whose histologic characteristics are intermediate between poorly differentiated and well differentiated.


Double Hit Lymphoproliferative Lesion

description: A lymphoproliferative lesion in which there are two genetic events involved in its pathogenesis.


Refractory Urothelial Carcinoma

description: Urothelial carcinoma that does not respond to treatment.


Nuclear Cataract Grade 1

description: A stage of nuclear sclerotic cataract marked by mild yellowing and sclerosis of the lens nucleus. (Modified LOCS II)


Adult Rhabdomyosarcoma

description: An aggressive malignant mesenchymal neoplasm arising from skeletal muscle in adults.


name: Recurrent Laryngeal Nerve Intra-Operative Injury, CTCAE


name: Grade 4 Genitourinary Stoma Stricture or Stenosis, CTCAE


Grade 2 Thrush, CTCAE

description: Oral intervention indicated (e.g., antifungal)


name: Rheumatoid Polyneuropathy with Rheumatoid Arthritis of Left Hand

description: Evidence of rheumatoid polyneuropathy with rheumatoid arthritis of left hand.


name: Exhaled Carbon Monoxide Concentration Less than or Equal to 5 ppm

description: An indication that the concentration of carbon monoxide (CO) in a sample of exhaled air is less than or equal to 5 ppm.


name: Grade 1 Infusion Site Extravasation, CTCAE

description: Painless edema


Grade 3 Facial Muscle Weakness, CTCAE

description: Severe symptoms; limiting self care ADL


name: Other transient cerebral ischemic attacks and related syndromes

description: Evidence of other transient cerebral ischemic attacks and related syndromes not specified elsewhere.


Paratesticular Endometrioid Tumor

description: A group of very rare tumors with endometrioid epithelial differentiation arising from the paratesticular structures. It includes benign tumors, borderline tumors (tumors with atypical epithelial proliferation), and malignant tumors (endometrioid adenocarcinomas).


name: Stage IVA Gestational Trophoblastic Tumor AJCC v7

description: Stage IVA includes: Any T, M1b, Risk factors: low risk.  M1b: All other distant metastasis.  (AJCC 7th ed.)


name: Grade 5 Thrombosis or Embolism Vascular Access Related, CTCAE


Refractory Malignant Glioma

description: Malignant glioma that does not respond to treatment.


name: Other Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma, Intra-abdominal Lymph Nodes

description: Evidence of other mature T-cell and NK-cell non-Hodgkin lymphoma in the intra-abdominal lymph nodes not specified elsewhere.


Myocardial Injury by T1 mapping

description: Regional or global myocardial injury as suggested by T1-weighted images.


Grade 2 Urostomy Obstruction, CTCAE

description: Symptomatic; dilation or endoscopic repair or stent placement indicated


name: Childhood Acute Lymphoblastic Leukemia Toronto Guidelines v2, Tier 2

description: A term that refers to the staging of childhood acute lymphoblastic leukemia according to the tier 2 Toronto childhood cancer staging guidelines v2.


Smooth Nodule

description: Featureless margin that cleanly demarcates the nodule from surrounding lung with no undulations or irregularities.


Rheumatoid Bursitis, Left Shoulder

description: Evidence of rheumatoid bursitis in the left shoulder.


Dry Mouth, CTCAE

description: A disorder characterized by reduced salivary flow in the oral cavity.


Retinoblastoma cT1c TNM Finding v7

description: At least one tumor is greater than 3 mm in largest dimension or located closer than 1.5 mm to the optic nerve or fovea, with retinal detachment or subretinal fluid beyond 5 mm from the base of the tumor.  (from AJCC 7th Ed.)


Kawasaki Disease Laboratory Finding

description: The laboratory findings indicating diagnosis of Kawasaki disease. The criteria for incomplete Kawasaki disease are: 1) Elevated ESR or CRP 2) Sterile pyuria 3) Anemia 4) Decreased albumin 5) Elevated alanine aminotransferase 6) Leukocytosis 7) Thrombocytosis. (ACC/AHA)


name: Bilateral hypertension with disorder of retinas

description: Evidence of hypertensive retinopathy that is bilateral.


name: Grade 4 Sinus Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


name: Grade 1 Bronchus Obstruction and Stenosis, CTCAE


Oropharyngeal Cancer TNM Finding v6

description: A finding about one or more characteristics of oropharyngeal cancer, following the rules of the TNM AJCC v6 classification system.


Retinopathy, CTCAE

description: A disorder involving the retina.


name: Papillary, Follicular, Hurthle Cell, Poorly Differentiated, and Anaplastic Thyroid Carcinoma Pathologic Distant Metastasis TNM Finding v8

description: A pathologic finding about one or more characteristics of papillary, follicular, Hurthle cell, poorly differentiated, and anaplastic thyroid carcinoma, following the rules of the TNM AJCC v8 classification system as they pertain to distant metastases.


Grade 2 Gallbladder Fistula, CTCAE

description: Symptomatic, invasive intervention not indicated


name: Hypopharyngeal Cancer pN3 TNM Finding v8

description: Hypopharyngeal cancer with metastasis in a lymph node larger than 6 cm in greatest dimension and ENE(-); or metastasis in a single ipsilateral lymph node larger than 3 cm in greatest dimension and ENE(+); or metastases in multiple ipsilateral, contralateral, or bilateral lymph nodes any with ENE(+). (from AJCC 8th Ed.)


Malignant Neoplasm by Grade

description: A term that refers to the categorization of malignant neoplasm by histologic grade.


Grade 1 Hot Flashes, CTCAE

description: Mild symptoms; intervention not indicated


name: Appendiceal Carcinoma cM1a TNM Finding v7

description: Appendiceal carcinoma with intraperitoneal metastasis beyond the right lower quadrant, including pseudomyxoma peritonei. (from AJCC 7th Ed.)


Stage IIA Cervical Cancer FIGO 2009

description: Cervical carcinoma limited to the upper two-thirds of the vagina. (FIGO 2009)


name: Grade 5 Brain and Spinal Cord Infection with Unknown Absolute Neutrophil Count, CTCAE


Breast Cancer TNM Finding v8

description: A finding about one or more characteristics of breast cancer, following the rules of the TNM AJCC v8 classification system. This classification system applies to invasive (infiltrating) carcinoma of the breast and ductal carcinoma in situ of the breast. It does not apply to breast sarcoma, phyllodes tumor, and breast lymphoma. (from AJCC 8th Ed.)


name: Leiomyosarcoma and Endometrial Stromal Sarcoma pT3a TNM Finding v7

description: Tumor infiltrates abdominal tissues, one site. (from AJCC 7th Ed.)


Toxic polyneuropathy

description: Polyneuropathy that is caused by exposure to toxins.


name: Type 1 Diabetes Mellitus with Diabetic Macular Edema, Resolved following Treatment, Left Eye

description: Evidence of type 1 diabetes mellitus with diabetic macular edema which is resolved following treatment in the left eye.


name: Cutaneous T-Cell Lymphoma, Unspecified, Lymph Nodes of Inguinal Region and Lower Limb

description: Evidence of unspecified cutaneous T-cell lymphoma in the lymph nodes of inguinal region and lower limb.


Perinatal Brain Injury

description: Injury to the brain of a newborn infant occurring around the time of birth.


Renal Hemorrhage, CTCAE

description: A disorder characterized by bleeding from the kidney.


Opisthorchis viverrini Infection

description: An infection caused by the parasite Opisthorchis viverrini. It results from the ingestion of raw or undercooked food. The clinical features vary from mild to severe and include gastrointestinal symptoms, anorexia, weight loss, hepatomegaly, and cholangitis. Patients are at an increased risk of developing cholangiocarcinoma.


name: Lung Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


name: Recurrent Fallopian Tube Undifferentiated Carcinoma

description: The reemergence of fallopian tube undifferentiated carcinoma after a period of remission.


name: Grade 4 Sinus Intra-Operative Injury, CTCAE


name: Merkel Cell Carcinoma pT4 TNM Finding v7

description: Merkel cell carcinoma with primary tumor invading bone, muscle, fascia, or cartilage. (from AJCC 7th Ed.)


name: Merkel Cell Carcinoma of Right Lower Limb, Including Hip

description: Evidence of Merkel cell carcinoma of right lower limb including the hip.


name: Activated Partial Thromboplastin Time Prolonged, CTCAE

description: A finding based on laboratory test results in which the partial thromboplastin time is found to be greater than the control value. As a possible indicator of coagulopathy, a prolonged partial thromboplastin time (PTT) may occur in a variety of diseases and disorders, both primary and related to treatment.


name: Grade 5 CNS Cerebrovascular Ischemia, CTCAE


name: Esophagus and Esophagogastric Junction Cancer Pathologic Regional Lymph Nodes TNM Finding v7

description: A pathologic finding about one or more characteristics of esophagus and esophagogastric junction cancer, following the rules of the TNM AJCC v7 classification system as they pertain to staging of regional lymph nodes.


Conjunctival Lymphangioma

description: A lymphangioma that arises from the conjunctiva.


perinatal respiratory distress

description: A pathological increase in the effort and frequency or breathing movements during the perinatal period.


Castleman Disease, Plasma Cell Type

description: Castleman disease characterized by the presence of prominent hyalinized vessels in the germinal centers and prominent sheets of plasma cells in the interfollicular areas.


Alcohol Use Complicating Childbirth

description: Evidence of alcohol use complicating childbirth.


name: Ampulla of Vater Cancer Clinical TNM Finding v8

description: A clinical finding about one or more characteristics of ampulla of Vater cancer, following the rules of the TNM AJCC v8 classification system.


name: Grade 3 Lip Or Perioral Area Intra-Operative Injury, CTCAE


name: Vaso-Occlusive Crisis in Sickle Cell-SS Disease

description: Sickle cell-SS disease exacerbated by sudden pain caused by sickled erythrocytes impeding blood flow within a vessel.


Grade 2 Neonatal Convulsion, AE

description: An adverse event in a newborn characterized by suspected seizures controlled with one anti-seizure drug (no recurrence within three days after treatment).


Gallbladder Cancer cM1 TNM Finding v8

description: Gallbladder cancer with distant metastasis. (from AJCC 8th Ed.)


Grade 4 Vaginal Infection, CTCAE

description: Life-threatening consequences; urgent intervention indicated


name: Fallopian Tube Cancer pTX TNM Finding v7

description: Fallopian tube cancer in which the primary tumor cannot be assessed. (from AJCC 7th Ed.)


ATM Deficient Tumor

description: A finding indicating that the expression of ATM in a tumor sample is aberrantly low or undetectable.


Cervical Cancer pT2a2 TNM Finding v8

description: Cervical carcinoma invading beyond the uterus but not to the pelvic wall or to lower third of vagina without parametrial invasion. Clinically visible lesion more than 4.0 cm in greatest dimension. (from AJCC 8th Ed.)


CALLA Positive Lymphoblastic Leukemia

description: Acute lymphoblastic leukemia which is positive for the common acute lymphoblastic leukemia antigen.


Scaly Skin Eruption

description: Peeling skin patches. Causes include psoriasis, eczema, and sunburns.


name: Conjunctival Carcinoma pM1 TNM Finding v8

description: Conjunctival carcinoma with distant metastasis. (from AJCC 8th Ed.)


name: Grade 3 Leukoencephalopathy Radiographic Findings, CTCAE


Jaccoud Arthropathy, Right Knee

description: Evidence of Jaccoud arthropathy in the right knee.


name: Rheumatoid Arthritis with Rheumatoid Factor of Right Shoulder without Organ or Systems Involvement

description: Evidence of rheumatoid arthritis with rheumatoid factor of right shoulder without organ or systems involvement.


name: Cerebral Infarction due to Unspecified Occlusion or Stenosis of Right Middle Cerebral Artery

description: Evidence of cerebral infarction due to an unspecified occlusion or stenosis of the right middle cerebral artery.


Movements Involuntary, CTCAE

description: A disorder characterized by uncontrolled and purposeless movements.


name: Ocular Adnexal Lymphoma pM1b TNM Finding v8

description: Ocular adnexal lymphoma with lymphomatous involvement of the bone marrow. (from AJCC 8th Ed.)


Gastric Mixed Adenocarcinoma

description: An adenocarcinoma that arises from the gastric mucosa and is characterized by the presence of both glandular and poorly cohesive malignant cellular components.


CT Image Artifact

description: An artifact in a CT image.


name: Grade 2 Postoperative Thoracic Procedure Complication, CTCAE

description: Extubated within 24-72 hrs postoperatively


Grade 2 Rectal Mucositis, CTCAE

description: Symptomatic; medical intervention indicated; limiting instrumental ADL


Grade 3 Lymph Leakage, CTCAE

description: Severe symptoms; invasive intervention indicated


Liposarcoma non-metastatic

description: Liposarcoma that is confined to a specific site without evidence of spread to other anatomic sites.


Non-Neoplastic Disorder

description: Any disorder other than abnormal tissue growth resulting from uncontrolled cell proliferation.


name: Stage II Ampulla of Vater Neuroendocrine Tumor AJCC v8

description: Stage II includes: (T2, N0, M0); (T3, N0, M0). T2: Tumor invading through the sphincter of Oddi into duodenal submucosa or muscularis propria, or measuring more than 1 cm. T3: Tumor invading the pancreas or peripancreatic adipose tissue. N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 8th ed.)


name: Locally Advanced Midgut Neuroendocrine Tumor

description: A midgut neuroendocrine tumor that has spread from its original site of growth to nearby tissues or lymph nodes.


name: Diabetes Mellitus due to Underlying Condition with Proliferative Diabetic Retinopathy with Traction Retinal Detachment not Involving the Macula, Bilateral

description: Evidence of diabetes mellitus due to underlying condition with proliferative diabetic retinopathy with traction retinal detachment not involving the macula that is bilateral.


name: Grade 5 Genitourinary Stoma Hemorrhage, CTCAE


name: Lugano Classification Stage II Bulky Childhood Hodgkin Lymphoma AJCC v8

description: Stage II Bulky: Stage II with disease bulk. (from AJCC 8th Ed.)


Increased Red Cell Mass

description: An indication that the portion of total blood volume occupied by erythrocytes in a sample have increased when compared to normal levels or a previous measurement.


name: Grade 3 Cartilage Intra-Operative Injury, CTCAE


name: Central Nervous System Vascular Malformations

description: A congenital abnormality of the arteries and veins that is located in the brain or spina cord, and which may increase the risk of bleeding, possibly resulting in impaired mental or physical function.


name: Mixed Cellularity Classic Hodgkin Lymphoma, Lymph Nodes of Inguinal Region and Lower Limb

description: Evidence of mixed cellularity classic Hodgkin lymphoma, lymph nodes of inguinal region and lower limb.


name: Malignant Neoplasm of Overlapping Sites of Bone and Articular Cartilage of Unspecified Limb

description: Evidence of a malignant neoplasm of overlapping sites of the bone and articular cartilage of unspecified limb.


name: Renal Pelvis and Ureter Cancer pT1 TNM Finding v8

description: Renal pelvis and ureter cancer in which the tumor invades subepithelial connective tissue. (from AJCC 8th Ed.)


CD3 Negative

description: An indication that expression of CD3 has not been detected in a sample.


Prostate Cancer cT3 TNM Finding v7

description: Prostate cancer extending through the prostatic capsule.  Invasion into the prostatic apex or into (but not beyond) the prostatic capsule is classified not as T3 but as T2. (from AJCC 7th Ed.)


name: Cerebral Infarction due to Thrombosis Unspecified Cerebral Artery

description: Evidence of cerebral infarction due to a thrombosis of an unspecified cerebral artery.