N3 TNM Finding

description: A general term that refers to a TNM finding of cancer metastases in multiple lymph nodes. The definition of N3 TNM finding depends on the specific type of cancer that it refers to; for example, for breast cancer it refers to metastases in 10 or more axillary lymph nodes; for cutaneous melanoma it refers to metastases in 4 or more regional lymph nodes; for gastric cancer it refers to metastases in 7 or more regional lymph nodes; and for bladder cancer it refers to metastases in common iliac lymph nodes.


Grade 2 Anorgasmia, CTCAE

category: biolink:PhenotypicFeature biolink:DiseaseOrPhenotypicFeature biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing

description: Inability to achieve orgasm adversely affecting relationship


Eyelid Carcinoma pT3 TNM Finding v8

description: Eyelid carcinoma with tumor measuring more than 20 mm but 30 mm or less in greatest dimension. (from AJCC 8th Ed.)


name: Grade 3 Scrotum Intra-Operative Injury, CTCAE


name: Other Rheumatoid Arthritis with Rheumatoid Factor of Left Hand

category: biolink:Disease biolink:DiseaseOrPhenotypicFeature biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing

description: Evidence of other rheumatoid arthritis with rheumatoid factor of left hand not specified elsewhere.


name: Ampulla of Vater Cancer pN2 TNM Finding v8

description: Ampulla of Vater cancer with metastasis to four or more regional lymph nodes. (from AJCC 8th Ed.)


Grade 3 Gallbladder Fistula, CTCAE

description: Invasive intervention indicated


name: Grade 3 Intraoperative Arterial Injury, CTCAE

description: Complete resection or reconstruction of injured organ/structure indicated; limiting self care ADL


name: Unspecified Malignant Neoplasm Skin of Left Lower Limb, Including Hip

description: Evidence of unspecified malignant neoplasm skin of the left lower limb including the hip.


name: Small Intestine Cancer pT3 TNM Finding v8

description: Small intestine cancer with tumor invading through the muscularis propria into the subserosa, or extending into nonperitonealized perimuscular tissue (mesentery or retroperitoneum) without serosal penetration. For T3 tumors, the nonperitonealized perimuscular tissue is, for the jejunum and ileum, part of the mesentery and, for the duodenum in areas where serosa is lacking, part of the interface with the pancreas. (from AJCC 8th Ed.)


name: Rheumatoid Myopathy with Rheumatoid Arthritis of Left Shoulder

description: Evidence of rheumatoid myopathy with rheumatoid arthritis of left shoulder.


Grade 2 Laryngeal Mucositis, CTCAE

description: Moderate pain, analgesics indicated; altered oral intake; limiting instrumental ADL


name: Grade 4 Peripheral Nerve Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


name: atherosclerosis of other type of bypass graft of right leg with ulceration of calf

description: Evidence of atherosclerosis of other type of bypass graft(s) of the right leg with ulceration of calf.


name: Other Myeloid Leukemia not Having Achieved Remission

description: Evidence of other myeloid leukemia not having achieved remission not specified elsewhere.


name: Grade 1 Infections and Infestations - Other, Specify, CTCAE

description: Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated


name: Hodgkin's Disease, Nodular Sclerosis, Lymphocyte Depletion


Grade 1 Kidney Anastomotic Leak, CTCAE

description: Asymptomatic diagnostic finding; intervention not indicated


Grade 4 Night Blindness, CTCAE

description: Best corrected visual acuity of 20/200 or worse in the affected eye


name: Carcinoma in Situ of Skin of Left Eyelid, Including Canthus

description: Evidence of carcinoma in situ of the skin of left eyelid including the canthus.


name: Oropharyngeal (p16-Negative) Cancer Pathologic Regional Lymph Nodes TNM Finding v8

description: A pathologic finding about one or more characteristics of oropharyngeal (p16-negative) cancer, following the rules of the TNM AJCC v8 classification system as they pertain to staging of regional lymph nodes.


Lung Cancer Pathologic TNM Finding v6

description: A pathologic finding about one or more characteristics of lung cancer, following the rules of the TNM AJCC v6 classification system.


name: Platinum-Resistant Malignant Germ Cell Tumor

description: A malignant germ cell tumor that is resistant to platinum therapy.


Retinoblastoma pN1 TNM Finding v7

description: Retinoblastoma with regional lymph node involvement (preauricular, cervical). (from AJCC 7th Ed.)


name: Carcinoma of the Eyelid pT0 TNM Finding v7

description: Carcinoma of the eyelid with no evidence of a primary tumor. (from AJCC 7th Ed.)


name: Left Anterior Middle Transition Zone of Prostate

description: The region of the prostate that is located on the anatomical left side of the anterior portion of the middle division of the transition zone.


name: Adult Unfavorable Prognosis Hodgkin Lymphoma

description: A Hodgkin lymphoma with unfavorable prognosis that occurs during adulthood.


Mycosis fungoides of spleen

description: Evidence of mycosis fungoides, spleen.


name: Distal Bile Duct Cancer pM1 TNM Finding v8

description: Distal bile duct cancer with distant metastasis. (from AJCC 8th Ed.)


name: Grade 3 Lip or Perioral Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


Mycotic pericarditis

description: Pericarditis that is caused by an infection with a fungal agent.


name: Grade 4 Ureter Intra-Operative Injury, CTCAE


name: Hypertensive Heart and Chronic Kidney Disease without Heart Failure, with Stage 5 Chronic Kidney Disease, or End Stage Renal Disease

description: Evidence of hypertensive heart and chronic kidney disease without heart failure, with stage 5 chronic kidney disease, or end stage renal disease.


name: Grade 1 Small Intestinal Obstruction, CTCAE

description: Asymptomatic; clinical or diagnostic observations only; intervention not indicated


name: Type 2 Diabetes Mellitus with Proliferative Diabetic Retinopathy with Macular Edema, Left Eye

description: Evidence of type 2 diabetes mellitus with proliferative diabetic retinopathy with macular edema in the left eye.


name: Maxillary Sinus Cancer pN2a TNM Finding v6 and v7

description: Maxillary sinus cancer with metastasis to a single ipsilateral lymph node, more than 3 cm, but not more than 6 cm in greatest dimension. (from AJCC 6th and 7th Eds.)


Grade 5 Pulmonary Fistula, CTCAE

description: Death


Eyes Partial Response GvHD

description: An NIH eye score that has decreased by 1 or more points.


Breast Cancer pN1 TNM Finding v6

description: Breast cancer with metastasis to 1 to 3 axillary lymph nodes, and/or internal mammary nodes with microscopic disease detected by sentinel lymph node dissection but not clinically apparent. (from AJCC 6th Ed.)


Cervical Cancer cT3b TNM Finding v8

description: Cervical cancer extending to pelvic wall and/or causing hydronephrosis or nonfunctioning kidney. (from AJCC 8th Ed.)


name: Secondary malignant neoplasm of brain and cerebral meninges

description: Evidence of secondary malignant neoplasm of brain and cerebral meninges.


name: Grade 3 Cervix Infection with Unknown Absolute Neutrophil Count, CTCAE


name: Metastatic malignant neoplasm to conjunctiva

description: A malignant neoplasm that has spread to the conjunctiva from another anatomic site.


name: Anaplastic (Malignant) Intracranial Meningioma

description: An anaplastic meningioma that arises within the cranial cavity.


Grade 1 INR Increased, CTCAE

description: >1.2-1.5; >1-1.5 x baseline if on anticoagulation; monitoring only indicated


name: Hereditary factor XII deficiency disease

description: A rare autosomal recessive inherited bleeding disorder caused by deficiency of coagulation factor XII. It may be asymptomatic or manifest with bleeding.


Metastatic Vaginal Carcinoma

description: A carcinoma that arises from the vagina and has metastasized to another anatomic site.


name: Grade 1 Fallopian Tube Intra-Operative Injury, CTCAE


name: Pre-Existing Type 1 Diabetes Mellitus, in Pregnancy, Third Trimester

description: Evidence of pre-existing type 1 diabetes mellitus in the in pregnancy in the third trimester.


Global Partial Response

description: Regression of measurable disease with complete response in skin and nodes, blood and viscera categories not having complete response or noninvolvement and where no category has progressive disease. Partial response is also assigned when there is partial response in skin and no nodes, blood and viscera category has a progressive disease and if any category involved at baseline at least one has a complete or partial response.


Vaginal Cancer pT3 TNM Finding v7

description: Vaginal cancer extending to the pelvic wall.  Pelvic wall is defined as muscle, fascia, neurovascular structures, or skeletal portions of the bony pelvis.  (from AJCC 7th Ed.)


CTCAE v4 Grade 3

description: An adverse event that is medically significant but not life-threatening; or for which inpatient care or prolongation of hospitalization are indicated; or that is an important medical event that does not result in hospitalization, but may jeopardize the patient or may require intervention either to prevent hospitalization, to prevent the AE from becoming life-threatening or causing death; or that is disabling; or that results in persistent or significant disability, incapacity, or limitation of self care activities of daily living (ADLs, e.g., getting in and out of bed, dressing, eating, getting around inside, bathing, or using the toilet).


name: Neonatal Cerebral Infarction, Unspecified Side

description: Evidence of neonatal cerebral infarction, unspecified side.


name: Appendiceal Carcinoid pN1 TNM Finding v7

description: Appendiceal carcinoid with regional lymph node metastasis. (from AJCC 7th Ed.)


name: Gastrointestinal Stromal Tumor pT4 TNM Finding v7

description: Gastrointestinal stromal tumor with tumor size more than 10 cm in greatest dimension. (from AJCC 7th Ed.)


description: Evidence of cannabis dependence with psychotic disorder with delusions.


Grade 5 Gum Infection, CTCAE

description: Death


Grade 2 Anal Hemorrhage, CTCAE

description: Moderate symptoms; intervention indicated


name: Osteoclastic Giant Cell-Rich Tumor of Bone

description: A benign, intermediate, or malignant bone tumor characterized by the presence of osteoclast-like giant cells. Clinical presentation includes pain, edema, and decreased range of motion in the affected joint.


description: Evidence of toxic liver disease with chronic active hepatitis with ascites.


name: Grade 2 Oral Cavity or Gum Infection with Unknown Absolute Neutrophil Count, CTCAE


Metastatic endometrioid carcinoma

description: An endometrioid adenocarcinoma that has spread from its original site of growth to another anatomic site.


ERBB2/D17Z1 Copy Number Ratio Finding

description: A genetic copy number finding indicating the ratio of the number of signals for a probe targeting the ERBB2 gene to the number of signals for a probe targeting chromosome 17 alpha satellite repeats (D17Z1).


Testicular Cancer pT4 TNM Finding v7

description: Testicular cancer with tumor invading the scrotum with or without vascular/lymphatic invasion. (from AJCC 7th Ed.)


name: Clinical Stage IVA Gastroesophageal Junction Adenocarcinoma AJCC v8

description: Stage IVA includes: (T1-4a, N2, M0); (T4b, N0-2, M0); (Any T, N3, M0). T1: Tumor invades the lamina propria, muscularis mucosae, or submucosa. T2: Tumor invades the muscularis propria. T3: Tumor invades adventitia. T4a: Tumor invades the pleura, pericardium, azygos vein, diaphragm, or peritoneum. T4b: Tumor invades other adjacent structures, such as the aorta, vertebral body, or airway. N0: No regional lymph node metastasis. N1: Tumor with metastasis in one or two regional lymph nodes. N2: Tumor with metastasis in three to six regional lymph nodes. N3: Tumor with metastasis in seven or more regional lymph nodes. M0: No distant metastasis. (AJCC 8th ed.)


Targetoid Lesion

description: A red, edematous ring skin finding that may have a central dusky disk and an erythematous halo.


name: Absence Epileptic Syndrome, Intractable, with Status Epilepticus

description: Evidence of absence epileptic syndrome with status epilepticus that does not respond optimally to treatment.


description: Evidence of acute promyelocytic leukemia not having achieved remission.


Grade 3 Pulmonary Hypertension, CTCAE

description: Severe symptoms, associated with hypoxia, right heart failure; oxygen indicated


name: Grade 2 Thoracodorsal Nerve Intra-Operative Injury, CTCAE


name: Burkitt's lymphoma of intrathoracic lymph nodes

description: Evidence of Burkitt lymphoma in the intrathoracic lymph nodes.


name: Recurrent Malignant Neoplasm of Multiple Primary Sites

description: Reemergence of a malignant neoplasm of multiple primary sites after a period of remission.


name: Skin Squamous Cell Carcinoma or Other Skin Carcinomas pT3 TNM Finding v7

description: Skin squamous cell carcinoma or other skin carcinomas with tumor invasion of maxilla, mandible, orbit, or temporal bone. (from AJCC 7th Ed.)


Grade 4 Anal Ulcer, CTCAE

description: Life-threatening consequences; urgent operative intervention indicated


name: Small Cell B-Cell Lymphoma, Extranodal and Solid Organ Sites

description: Evidence of small cell B-cell lymphoma in the extranodal and solid organ sites.


Thalassemic Osteopathy

description: Bone disorders that present in thalassemia patients.


name: Cognitive Side Effects of Cancer Therapy

description: Cognitive impairment caused by cancer treatment.


name: Juvenile Rheumatoid Arthritis with Systemic Onset, Unspecified Hip

description: Evidence of juvenile rheumatoid arthritis with systemic onset in an unspecified hip.


Activity at Injection Site

description: An artifact resulting from excess signal at the injection site.


Retinoblastoma pT1 TNM Finding v7

description: Retinoblastoma with tumor confined to eye with no optic nerve or choroidal invasion. (from AJCC 7th Ed.)


name: Other Classic Hodgkin Lymphoma, Extranodal and Solid Organ Sites

description: Evidence of other classic Hodgkin lymphoma in the extranodal and solid organ sites not specified elsewhere.


Multicentric Lesion

description: A term that usually refers to cancer growth and is defined by the presence of multiple lesions, each originating from a different clonal cellular population.


name: Grade 5 Blood Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


name: Appendiceal Carcinoma pT4a TNM Finding v7

description: Appendiceal carcinoma with tumor penetrating visceral peritoneum including mucinous peritoneal tumor within the right lower quadrant. (from AJCC 7th Ed.)


name: Prostate Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


name: Major depression single episode, in partial remission

description: Evidence of major depressive disorder that is a single episode and is in partial remission.


Plate-reader Artifact

description: Artifacts resulting from the electronics of the plate reader or from issues associated with the image plate.


name: Type 1 Diabetes Mellitus with Unspecified Diabetic Retinopathy with Macular Edema

description: Evidence of type 1 diabetes mellitus with unspecified diabetic retinopathy with macular edema.


name: Mycosis fungoides of intrapelvic lymph nodes

description: Evidence of mycosis fungoides, intrapelvic lymph nodes.


name: Drug or Chemical Induced Diabetes Mellitus with Hyperglycemia

description: Evidence of drug or chemical induced diabetes mellitus with hyperglycemia.


Genetic Predisposition to Disease

description: The predisposition of an individual to develop a specific disease based on their heredity.


name: Pre-Existing Hypertensive Heart and Chronic Kidney Disease Complicating Pregnancy, Second Trimester

description: Evidence of pre-existing hypertensive heart and chronic kidney disease complicating pregnancy in the second trimester.


Malignant neoplasm of fundus uteri

description: Evidence of a malignant neoplasm of the fundus uteri.


name: Breast Fibrocystic Change, Proliferative Type without Atypia

description: Breast fibrocystic change characterized by the presence of epithelial cell hyperplasia.  There is no evidence of epithelial atypia.


name: Grade 2 Personality and Behavioral Change, CTCAE


name: Monoplegia of Lower Limb following Non-Traumatic Intracerebral Hemorrhage Affecting Left Dominant Side

description: Evidence of monoplegia of lower limb following non-traumatic intracerebral hemorrhage affecting left dominant side.


Grade 1 Retinal Tear, CTCAE

description: No retinal detachment and treatment not indicated


Paronychia, CTCAE

description: A disorder characterized by an infectious process involving the soft tissues around the nail.


Cutaneous Melanoma pM1a TNM Finding v7

description: Cutaneous melanoma with metastases to skin, subcutaneous tissues, or distant lymph nodes associated with normal serum lactate dehydrogenase (LDH). (from AJCC 7th Ed.)


Rheumatoid Nodule, Left Knee

description: Evidence of rheumatoid nodule in the left knee.


name: Diabetes Mellitus due to Underlying Condition with Moderate Non-Proliferative Diabetic Retinopathy with Macular Edema, Unspecified Eye

description: Evidence of diabetes mellitus due to underlying condition with moderate non-proliferative diabetic retinopathy with macular edema in an unspecified eye.


Cervical Neuroendocrine Tumor G1

description: A well-differentiated, low grade neuroendocrine neoplasm that arises from the cervix.


name: Drug Use Complicating Pregnancy, Unspecified Trimester

description: Evidence of drug use complicating pregnancy in an unspecified trimester.


Grade 4 Duodenal Hemorrhage, CTCAE

description: Life-threatening consequences; urgent intervention indicated


name: Ampulla of Vater Cancer pT0 TNM Finding v7

description: Ampulla of Vater cancer with no evidence of primary tumor. (from AJCC 7th Ed.)


PSA Level Zero to Two

description: A blood concentration of prostate specific antigen between 0 ng/mL and 2 ng/mL.


Cyanosis, CTCAE

description: A disorder characterized by a bluish discoloration of the skin and/or mucous membranes.


Eyelid Carcinoma pN1b TNM Finding v8

description: Eyelid carcinoma with metastasis in a single ipsilateral regional lymph node, measuring 3 cm or less in greatest dimension based on lymph node biopsy. (from AJCC 8th Ed.)


name: Nodular Lymphocyte Predominant Hodgkin Lymphoma, Lymph Nodes of Head, Face, and Neck

description: Evidence of nodular lymphocyte predominant Hodgkin lymphoma in the lymph nodes of head, face, and neck.


Low ADAMTS13 Activity

description: A finding indicating that a significantly lower than expected activity for the proteinase a disintegrin and metalloproteinase with thrombospondin motifs 13 (ADAMTS13) is detected in a sample. This finding is associated with thrombotic thrombocytopenic purpura.


Granular Cell Astrocytoma

description: An astrocytoma characterized by the presence of large numbers of neoplastic cells with granular, PAS-positive cytoplasm. It is associated with an aggressive clinical course, even when the histologic features suggest a lower-grade astrocytoma.


name: Ocular Adnexal Lymphoma pT2c TNM Finding v7

description: Posterior orbital involvement (+/- conjunctival involvement +/- anterior involvement and +/- any extraocular muscle involvement). (from AJCC 7th Ed.)


name: High Grade Conjunctival Squamous Intraepithelial Neoplasia

description: A precancerous neoplastic intraepithelial process with high-grade dysplastic features involving the conjunctival epithelium.


Grade 3 Gum Infection, CTCAE

description: IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated


name: Grade 2 Fallopian Tube Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


name: Skin Squamous Cell Carcinoma or Other Skin Carcinomas TNM Finding v7

description: A finding about one or more characteristics of skin squamous cell carcinoma or other nonmelanoma skin carcinomas excluding Merkel cell carcinoma, following the rules of the TNM AJCC v7 classification system.  (from AJCC 7th Ed.)


name: Clinical Stage II Gastroesophageal Junction Adenocarcinoma AJCC v8

description: Stage II includes: IIA: T1, N1, M0; IIB: T2, N0, M0. T1: Tumor invades the lamina propria, muscularis mucosae, or submucosa. T2: Tumor invades the muscularis propria. N0: No regional lymph node metastasis. N1: Tumor with metastasis in one or two regional lymph nodes. M0: No distant metastasis. (AJCC 8th ed.)


Grade 5 Pancreatic Duct Stenosis, CTCAE

description: Death


name: Intraoperative Reproductive System Injury

description: Damage to the reproductive organs during a surgical procedure.


name: Colon or Rectum Neuroendocrine Tumor Pathologic Distant Metastasis TNM Finding v7

description: A pathologic finding about one or more characteristics of colon or rectum neuroendocrine tumor, following the rules of the TNM AJCC v7 classification system as they pertain to distant metastases.  There is no pathologic M0 for colon or rectum neuroendocrine tumor. (from AJCC 7th Ed.)


name: Grade 5 Fallopian Tube Hemorrhage, CTCAE


Grade 2 Hip Fracture, CTCAE

description: Hairline fracture; mild pain; limiting instrumental ADL; non-operative intervention indicated


Activating KRAS Gene Mutation Negative

description: A genetic finding indicating that mutations in the KRAS gene which encode constitutively active forms of the GTPase KRas protein are not present in a sample.


name: Appendiceal Carcinoma pM1c TNM Finding v8

description: Appendiceal carcinoma with metastasis to sites other than peritoneum. (from AJCC 8th Ed.)


Grade 5 Portal Vein Thrombosis, CTCAE

description: Death


Nuclear Cataract Grade 2

description: A stage of nuclear sclerotic cataract marked by moderate yellowing and sclerosis of the lens nucleus. (Modified LOCS II)


name: Small Intestine Cancer Pathologic Regional Lymph Nodes TNM Finding v7

description: A pathologic finding about one or more characteristics of small intestine cancer, following the rules of the TNM AJCC v7 classification system as they pertain to staging of regional lymph nodes.


name: Ovarian, Fallopian Tube, and Primary Peritoneal Carcinoma Pathologic TNM Finding v8

description: A pathologic finding about one or more characteristics of ovarian, fallopian tube, or primary peritoneal carcinoma, following the rules of the TNM AJCC v8 classification system.


name: Grade 3 Brain and Spinal Cord Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


Grade 1 Floaters, CTCAE

description: Symptomatic but not limiting ADL


Retinoblastoma, undifferentiated

description: A retinoblastoma composed of small, undifferentiated cells. It is often associated with necrotic changes.


KRAS Exon 2 Mutation Negative

description: A genetic finding indicating that KRAS exon 2 gene mutations have not been detected in a sample.


Pain, CTCAE

description: A disorder characterized by the sensation of marked discomfort, distress or agony.


name: Testicular Cancer Clinical Primary Tumor TNM Finding v8

description: A clinical finding about one or more characteristics of testicular cancer, following the rules of the TNM AJCC v8 classification system as they pertain to staging of the primary tumor.


name: Functional Test Result or Finding in Original Units

description: The outcome of the functional test assessment as originally received or collected.


Grade 3 Tinnitus, CTCAE

description: Severe symptoms; limiting self care ADL


Malignant tumor, small cell type

description: A malignant neoplasm characterized by the presence of small atypical cells.


name: Major Salivary Gland Cancer cN3 TNM Finding v8

description: Major salivary gland cancer with metastasis in a lymph node larger than 6 cm in greatest dimension and ENE(-); or metastasis in any node(s) with clinically overt ENE(+). (from AJCC 8th Ed.)


name: Occlusion and stenosis of unspecified cerebral artery

description: Evidence of occlusion and stenosis of unspecified cerebral artery.


name: Encounter for Fitting and Adjustment of Extracorporeal Dialysis Catheter

description: Evidence of encounter for fitting and adjustment of extracorporeal dialysis catheter.


name: Malignant Carcinoid Tumor of the Large Intestine, Unspecified Portion

description: Evidence of a malignant carcinoid tumor of the large intestine, unspecified portion.


Cervical Cancer cM0 TNM Finding v7

description: Cervical cancer in which there is no evidence of distant metastasis. (from AJCC 7th Ed.)


name: Atherosclerosis of Native Arteries of the Extremities with Gangrene, Right Leg

description: Evidence of atherosclerosis of native arteries of the extremities with gangrene in the right leg.


Stage IIC Prostate Cancer AJCC v8

description: Stage IIC includes: (T1-2, N0, M0, PSA less than 20, Grade Group 3); (T1-2, N0, M0, PSA less than 20, Grade Group 4). T1: Prostate cancer with clinically inapparent tumor that is not palpable. T2: Prostate cancer in which the tumor is palpable and confined within the prostate. N0: Prostate cancer with no positive regional nodes. M0: Prostate cancer without evidence of distant metastasis. Grade Group 3: Gleason Score 7, Gleason Pattern 4+3. Grade Group 4: Gleason Score 8, Gleason Pattern 4+4. (AJCC 8th ed.)


pM0 TNM Finding

description: No morphologic evidence of distant metastasis, in accordance with TNM classification system guidelines.


name: Skin Squamous Cell Carcinoma or Other Skin Carcinomas pN2b TNM Finding v7

description: Skin squamous cell carcinoma or other skin carcinomas with metastasis in multiple ipsilateral lymph nodes, none more than 6 cm in greatest dimension. (from AJCC 7th Ed.)


name: Post-Immunization Arthropathy, Left Ankle and Foot

description: Evidence of post-immunization arthropathy in the left ankle and foot.


name: Grade 4 Sinus Infection with Unknown Absolute Neutrophil Count, CTCAE


description: Evidence of acute megakaryoblastic leukemia not having achieved remission.


name: Other Psychoactive Substance Use, Unspecified with Psychoactive Substance-Induced Psychotic Disorder with Delusions

description: Evidence of other psychoactive substance use, unspecified with psychoactive substance-induced psychotic disorder with delusions not specified elsewhere.


name: malignant neoplasm of overlapping sites of right eye and adnexa

description: Evidence of a malignant neoplasm of overlapping sites of the right eye and adnexa.


Delusional disorder, somatic type

description: A subtype of delusional disorder characterized by the central delusional theme that the individual has some physical defect or medical condition.


Grade 2 Duodenal Hemorrhage, CTCAE

description: Moderate symptoms; intervention indicated


Gallbladder Cancer pTX TNM Finding v8

description: Gallbladder cancer in which the primary tumor cannot be assessed. (from AJCC 8th Ed.)


Urinary Fistula, CTCAE

description: A disorder characterized by an abnormal communication between any part of the urinary system and another organ or anatomic site.


Oral Complication

description: Any oral disorder occurring as a consequence of injury to the mouth and lips.


name: Grade 3 Neonatal Pulmonary Hemorrhage, AE

description: An adverse event in a newborn characterized by hemorrhagic secretion in an endotracheal (ET) tube; with relevant increase in partial pressure of carbon dioxide (pCO2) or decrease in oxygenation; requiring major change in ventilatory support or transfusion.


name: Type 2 Diabetes Mellitus with Proliferative Diabetic Retinopathy with Macular Edema, Unspecified Eye

description: Evidence of type 2 diabetes mellitus with proliferative diabetic retinopathy with macular edema in an unspecified eye.


name: Left Anterior Apical Peripheral Zone of Prostate

description: The region of the prostate that is located on the anatomical left side of the anterior portion of the apical division of the peripheral zone.


name: T Lymphoblastic Leukemia/Lymphoma, Not Otherwise Specified

description: T-lymphoblastic leukemia/lymphoma in which further genetic/molecular characterization is not available.


Prostate Cancer cT4 TNM Finding v7

description: Prostate cancer with fixed tumor or tumor invading adjacent structures other than seminal vesicles such as external sphincter, rectum, bladder, levator muscles, and/or pelvic wall. (from AJCC 7th Ed.)


Bladder Paraganglioma

description: An extra-adrenal sympathetic paraganglioma arising from the urinary bladder.  Clinical signs include hypertension and hematuria.


name: Follicular Lymphoma, Unspecified, Lymph Nodes of Axilla and Upper Limb

description: Evidence of unspecified follicular lymphoma in the lymph nodes of axilla and upper limb.


name: Adverse Event Associated with Ocular and Visual Systems


Grade 2 Night Blindness, CTCAE

description: Symptomatic; moderate decrease in visual acuity (best corrected visual acuity 20/40 and better or 3 lines or less decreased vision from known baseline); limiting instrumental ADL


name: Childhood Malignant Genitourinary System Neoplasm

description: A malignant neoplasm that affects the genitourinary system during childhood.


Broad Ligament Serous Adenocarcinoma

description: A rare serous adenocarcinoma that arises from the broad ligament.


Grade 5 Menorrhagia, CTCAE

description: Death


name: Grade 2 Larynx Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


H3 K27M Negative

description: An indication that expression of the histone H3 K27M mutation has not been detected in a sample.


name: Drug or Chemical Induced Diabetes Mellitus with Proliferative Diabetic Retinopathy without Macular Edema, Left Eye

description: Evidence of drug or chemical induced diabetes mellitus with proliferative diabetic retinopathy without macular edema in the left eye.


Other sarcomas of liver

description: Evidence of other sarcomas of liver not specified elsewhere.


name: Juvenile Rheumatoid Arthritis with Systemic Onset, Vertebrae

description: Evidence of juvenile rheumatoid arthritis with systemic onset in the vertebrae.


Eyelid Carcinoma cM1 TNM Finding v8

description: Eyelid carcinoma with distant metastasis. (from AJCC 8th Ed.)


name: Malignant Non-Hodgkin Lymphoma, Cleaved Cell


Epstein-Barr Virus Negative

description: An indication that Epstein-Barr virus has not been detected in a sample.


name: Vaginal Keratinizing Squamous Cell Carcinoma

description: A squamous cell carcinoma that arises from the vagina and is characterized by the presence of keratin pearls. Intercellular bridges and cytoplasmic keratinization are usually present.


Cutaneous neurofibroma

description: A neurofibroma that grows along small branches of nerves in the dermis in patients with neurofibromatosis. It presents as a solid cutaneous tumor.


Esophageal adenocarcinoma recurrent

description: An esophageal adenocarcinoma which has reappeared after a period of remission or after presumed treatment.


name: Rheumatic Disorders of Both Mitral and Tricuspid Valves

description: Evidence of rheumatic disorders of both mitral and tricuspid valves.


Grade 2 Gastric Fistula, CTCAE

description: Symptomatic, invasive intervention not indicated


Cervical Cancer by AJCC v7 Stage

description: A term that refers to the staging of cervical cancer according to the American Joint Committee on Cancer, 7th edition.


name: Sedative, Hypnotic or Anxiolytic Abuse with Sedative, Hypnotic or Anxiolytic-Induced Psychotic Disorder with Hallucinations

description: Evidence of sedative, hypnotic or anxiolytic abuse with sedative, hypnotic or anxiolytic-induced psychotic disorder with hallucinations.


Acute Myocardial Injury

description: Acute myocardial injury diagnosed by rise and fall in cardiac troponin above the 99th percentile of a reference population.


Stage IIA1 Cervical Cancer AJCC v9

description: Stage IIA1 includes: T2a1, N0, M0. T2a1: Tumor with involvement limited to the upper two-thirds of the vagina without parametrial invasion measuring 4.0 cm or less in greatest dimension. N0: No regional lymph node metastasis. M0: No distant metastasis. (from AJCC 9th Ed.)


name: Grade 4 Neutrophil Count Decreased, CTCAE

description: <500/mm3; <0.5 x 10e9/L


Hormone Treatment Failure

description: A lack of response to hormone therapy.


Conjunctival Spitz Nevus

description: A rare nevus that arises from the conjunctiva. It is characterized by the presence of large spindle-shaped or epithelioid melanocytes.


Prostate Undifferentiated Carcinoma

description: An invasive prostate carcinoma characterized by the presence of undifferentiated malignant cells.


Grade 3 Fibrinogen Decreased, CTCAE

description: <0.5-0.25 x LLN; if abnormal, 50-<75% decrease from baseline


Tinnitus, CTCAE 5.0

description: A disorder characterized by noise in the ears, such as ringing, buzzing, roaring or clicking.


Actinomycotic granuloma

description: A granuloma that develops in response to Actinomycotic fungal infection.


name: Grade 2 Intraoperative Hepatobiliary Injury, CTCAE

description: Partial resection of injured organ/structure indicated


Refractory Liposarcoma

description: Liposarcoma that does not respond to treatment.


Liver Cancer pT4 TNM Finding v7

description: Liver cancer with tumor(s) with direct invasion of adjacent organs other than the gallbladder or with perforation of visceral peritoneum. (from AJCC 7th Ed.)


Stage IV Cervical Cancer AJCC v6 and v7

description: Stage IV includes: IVA: (T4, Any N, M0); IVB (Any T, Any N, MI). T4: Tumor invades mucosa of bladder or rectum, and/or extends beyond true pelvis (bullous edema is not sufficient to classify a tumor as T4). M1: Distant metastasis. (AJCC 6th and 7th eds.)


name: Grade 1 Nails Intra-Operative Injury, CTCAE


name: Monoplegia of Upper Limb Affecting Left Dominant Side

description: Evidence of monoplegia of upper limb affecting left dominant side.


Fall, CTCAE

description: A finding of sudden movement downward, usually resulting in injury.


name: Grade 4 Stoma GI Stricture or Stenosis, CTCAE


Grade 5 Device Related Infection, CTCAE

description: Death


name: Type 1 Diabetes Mellitus with Severe Nonproliferative Diabetic Retinopathy without Macular Edema, Unspecified Eye

description: Evidence of type 1 diabetes mellitus with severe nonproliferative diabetic retinopathy without macular edema in an unspecified eye.


name: Skin Squamous Cell Carcinoma or Other Skin Carcinomas pTX TNM Finding v7

description: Skin squamous cell carcinoma or other skin carcinomas in which the primary tumor cannot be assessed. (from AJCC 7th Ed.)


name: Rheumatoid Heart Disease with Rheumatoid Arthritis of Right Knee

description: Evidence of rheumatoid heart disease with rheumatoid arthritis of right knee.


name: Grade 5 Liver Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


name: Grade 2 Aspartate Aminotransferase Increased, CTCAE

description: >3.0-5.0 x ULN if baseline was normal; >3.0-5.0 x baseline if baseline was abnormal


Grade 2 Seizure, CTCAE

description: Brief generalized seizure


ROS1 Gene Fusion Negative

description: An indication that a ROS1 fusion gene has not been detected in a sample.


Grade 4 Kidney Infection, CTCAE

description: Life-threatening consequences; urgent intervention indicated


name: Grade 5 Paranasal Infection with Unknown Absolute Neutrophil Count, CTCAE


Grade 5 Pancreatic Necrosis, CTCAE

description: Death


Grade 5 Hepatitis Viral, CTCAE

description: Death


name: Recurrent depressive disorder, current episode severe with psychotic symptoms

description: Evidence of major depressive disorder that is recurrent and severe with psychotic symptoms.


CD8 Negative

description: An indication that expression of the CD8 complex has not been detected in a sample.


Papular Lesion

description: A small (less than 5-10 mm) elevation of skin that is non-suppurative.


Retinoblastoma cT4 TNM Finding v7

description: Extraocular disease detected by imaging studies. (from AJCC 7th Ed.)


name: Pleural Mesothelioma pT1a TNM Finding v7

description: Pleural mesothelioma with no involvement of the visceral pleura. (from AJCC 7th Ed.)


name: Nasal Cavity and Ethmoid Sinus Cancer pT4 TNM Finding v8

description: Nasal cavity and ethmoid sinus cancer with moderately advanced or very advanced local disease. (from AJCC 8th Ed.)


name: Grade 3 Hepatobiliary Disorders - Other, Specify, CTCAE

description: Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL


Other Alzheimer's disease

description: Evidence of other Alzheimer's disease not specified elsewhere.


Anaplastic Astroblastoma, MN1-Altered

description: An astroblastoma, MN1-altered, characterized by the presence of high mitotic activity, cytologic atypia, and architectural distortion.


Grade 1 Neonatal Sinus Bradycardia, AE

description: An adverse event in a newborn characterized by brief, self-limiting, episodes of sinus bradycardia; no care changes.


Refractory Appendix Carcinoma

description: Appendix carcinoma that is resistant to treatment.


name: Grade 3 Upper Respiratory Infection, CTCAE

description: IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated


Alopecia, CTCAE

description: A disorder characterized by a decrease in density of hair compared to normal for a given individual at a given age and body location.


name: Maxillary Sinus Cancer Pathologic TNM Finding v6

description: A pathologic finding about one or more characteristics of maxillary sinus cancer, following the rules of the TNM AJCC v6 classification system.


name: Post-Immunization Arthropathy, Multiple Sites

description: Evidence of post-immunization arthropathy in multiple sites.


name: Grade 1 Left Ventricular Diastolic Dysfunction, CTCAE


Critical illness myopathy

description: Acute muscle weakness and paralysis that develops in critically ill patients who have been treated with multiple drugs during their intensive care unit stay. It is associated with delayed weaning from mechanical ventilation and prolonged rehabilitation.


name: Cerebral Infarction due to Embolism of Left Vertebral Artery

description: Evidence of cerebral infarction due to an embolism of the left vertebral artery.


Grade 5 Bladder Infection, CTCAE

description: Death


name: Follicular Lymphoma Grade I, Intrathoracic Lymph Nodes

description: Evidence of follicular lymphoma grade I in the intrathoracic lymph nodes.


name: Lugano Classification Limited Stage Adult Lymphoma AJCC v8

description: Limited stage adult lymphoma based on the Lugano classification criteria. It includes stages I, IE, II, and IIE. (from AJCC 8th Ed.)


name: Childhood Acute Lymphoblastic Leukemia CNS 2 Toronto Guidelines v2

description: No clinical signs of CNS involvement and blasts in CSF and either: WBC < 5/μL CSF or WBC > or = 5/uL CSF and RBC > or = 10/uL CSF and WBC/RBC in CSF < or = 2x WBC/RBC in blood. (Childhood cancer staging for population registries according to the Toronto Childhood Cancer Stage Guidelines - Version 2. Cancer Council Queensland and Cancer Australia: Brisbane, Australia; 2021.)


name: Encounter for Fitting and Adjustment of Peritoneal Dialysis Catheter

description: Evidence of encounter for fitting and adjustment of peritoneal dialysis catheter.


Cutaneous Melanoma cN1 TNM Finding v8

description: Cutaneous melanoma with one tumor-involved node or in-transit satellite, and/or microsatellite metastases with no tumor-involved nodes. (from AJCC 8th Ed.)


Perforation due to Lead

description: Penetration of a lead through a systemic vein, coronary vein, or the myocardium. (ACC)


name: Juvenile Arthritis, Unspecified, Right Wrist

description: Evidence of unspecified juvenile arthritis in the right wrist.


Stage IIIC Appendix Carcinoma AJCC v8

description: Stage IIIC includes: Any T, N2, M0. N2: Four or more regional lymph nodes are positive. M0: No distant metastasis. (AJCC 8th ed.)


name: Grade 1 Cranial Nerve II Neuropathy, CTCAE


Cutaneous Melanoma pT2 TNM Finding v8

description: Cutaneous melanoma measuring more than 1.0 and equal to or less than 2.0 mm in thickness. Ulceration status: Unknown or unspecified. (from AJCC 8th Ed.)


Cutaneous Melanoma cN0 TNM Finding v7

description: Cutaneous melanoma in which no regional metastases are detected. (from AJCC 7th Ed.)


name: Secondary and unspecified malignant neoplasm of lymph nodes of head, face and neck

description: Evidence of secondary and unspecified malignant neoplasm of lymph nodes of head, face and neck.


Grade 3 Tumor Pain, CTCAE

description: Severe pain; limiting self care ADL


description: Trigeminal neuralgia caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).


name: Grade 1 Sacral Plexus Intra-Operative Injury, CTCAE


Sensory Disorders

description: An interruption or alteration in the sensory activity or functions of the nervous system.


name: Grade 5 Genitourinary Stoma Prolapse, CTCAE


name: Diabetes Mellitus due to Underlying Condition with Diabetic Macular Edema, Resolved following Treatment, Unspecified Eye

description: Evidence of diabetes mellitus due to underlying condition with diabetic macular edema, which is resolved following treatment in an unspecified eye.


Portal Hypertension, CTCAE

description: A disorder characterized by an increase in blood pressure in the portal venous system.


name: Grade 2 Pharynx Infection with Unknown Absolute Neutrophil Count, CTCAE


Grade 3 Laryngeal Hemorrhage, CTCAE

description: Transfusion indicated; invasive intervention indicated; hospitalization


name: Alcohol Dependence with Unspecified Alcohol-Induced Disorder

description: Evidence of alcohol dependence with unspecified alcohol-induced disorder.


name: Grade 3 Genitourinary Stoma Stricture or Stenosis, CTCAE


name: Small Intestine Cancer pN1 TNM Finding v8

description: Small intestine cancer with metastasis in one or two regional lymph nodes. (from AJCC 8th Ed.)


Metastatic Merkel Cell Carcinoma

description: A Merkel cell carcinoma that has spread from the original site of growth to another anatomic site.


name: Aphasia following Unspecified Cerebrovascular Disease

description: Evidence of aphasia following unspecified cerebrovascular disease.


Endometrial Neuroendocrine Carcinoma

description: A small cell or large cell neuroendocrine carcinoma arising from the endometrium.


name: Ampullary Flat Intraepithelial Neoplasia, High Grade

description: A non-polypoid, preinvasive neoplasm that arises from the ampulla of Vater.  It is characterized by the presence of high grade dysplasia.


name: Chronic Ocular Graft Versus Host Disease

description: Chronic graft versus host disease occurring in the eye.


Grade 2 Hyperlipidemia, CTCAE

description: Requiring pharmaceutical intervention


name: Unspecified B-Cell Lymphoma, Extranodal and Solid Organ Sites

description: Evidence of unspecified B-cell lymphoma in the extranodal and solid organ sites.


Injury Asphyxation

description: Acute compression of the thoracic cavity, causing  increased intrathoracic pressure and the backflow of blood from the right atrium and superior vena cava into the brachiocephalic and jugular veins, with resulting stagnation of blood flow and subsequent localized blood-oxygen desaturation in the head and neck.


name: Breast Cancer pT4d TNM Finding v6 and v7

description: Breast cancer meeting the clinical-pathologic criteria of inflammatory carcinoma. (from AJCC 6th and 7th Eds.)


Grade 3 Hypertension, CTCAE

description: Adult: Systolic BP >=160 mm Hg or diastolic BP >=100 mm Hg; medical intervention indicated; more than one drug or more intensive therapy than previously used indicated; Pediatric and adolescent: Systolic and/or diastolic > 5 mmHg above the 99th percentile


name: Grade 1 Stomach Mucositis or Stomatitis by Functional or Symptomatic Classification, CTCAE


name: Oropharyngeal (p16-Negative) Cancer cM0 TNM Finding v8

description: Oropharyngeal (p16-negative) cancer without evidence of distant metastasis. (from AJCC 8th Ed.)


Appendiceal Carcinoid TNM Finding v7

description: A finding about one or more characteristics of appendiceal carcinoid, following the rules of the TNM AJCC v7 classification system.


Residual Tumor

description: Tumor cells that remain in the body following cancer treatment.


name: Grade 4 Vulva Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


Esophageal Basal Cell Hyperplasia

description: A reactive (non-neoplastic) hyperplastic process affecting the esophageal squamous epithelium that is caused by inflammation.  Morphologically it involves more than 15% of the thickness of the esophageal squamous epithelium.  Its association with an increase risk of developing squamous cell carcinoma remains controversial.


Grade 1 Chylous Ascites, CTCAE

description: Asymptomatic; clinical or diagnostic observations only; intervention not indicated


name: Grade 4 Urethra Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


Grade 3 Enterocolitis Infectious, CTCAE

description: IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated; profuse watery diarrhea with signs of hypovolemia; bloody diarrhea; fever; severe abdominal pain; hospitalization indicated


name: Grade 1 Blood Corticotrophin Decreased, CTCAE


Grade 3 Anal Stenosis, CTCAE

description: Symptomatic and severely altered GI function; non-emergent operative intervention indicated; TPN or hospitalization indicated


Grade 2 Scrotal Pain, CTCAE

description: Moderate pain; limiting instrumental ADL


name: Pathologic Stage IIIA Cutaneous Melanoma AJCC v8

description: Stage IIIA includes: T1a/b-T2a, N1a or N2a, M0. T1a: Tumor measuring less than 0.8 mm in thickness. Ulceration status: Without ulceration. T1b: Tumor measuring less than 0.8 mm in thickness with ulceration, or 0.8-1.0 mm with or without ulceration. T2a: Tumor measuring more than 1.0 and equal to or less than 2.0 mm in thickness. Ulceration status: Without ulceration. N1a: One clinically occult nodal metastasis (i.e., detected by sentinel lymph node biopsy). Presence of in-transit, satellite, and/or microsatellite metastases: No.  N2a: Two or three clinically occult nodal metastases (i.e., detected by sentinel lymph node biopsy). Presence of in-transit, satellite, and/or microsatellite metastases: No.  M0: No evidence of distant metastasis. LDH level is not applicable. (AJCC 8th ed.)


Mixed Response

description: An indication that some disease characteristics are improving while others are worsening over time.


Bone Cancer Pathologic TNM Finding v7

description: A pathologic finding about one or more characteristics of bone cancer, following the rules of the TNM AJCC v7 classification system.  The pathologic diagnosis is based on the microscopic examination of tissue, correlated with imaging studies. (from AJCC 7th Ed.)


description: Evidence of hallucinogen dependence with hallucinogen-induced psychotic disorder with hallucinations.


name: Postneoadjuvant Therapy Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8

description: Stage IV includes: IVA: (T4a, N1-2, M0); (T4a, NX, M0); (T4b, N0-2, M0); (Any T, N3, M0); IVB: (Any T, Any N, M1). T4a: Tumor invades the pleura, pericardium, azygos vein, diaphragm, or peritoneum. T4b: Tumor invades other adjacent structures, such as the aorta, vertebral body, or airway. NX: Regional lymph nodes cannot be assessed. N0: No regional lymph node metastasis. N1: Tumor with metastasis in one or two regional lymph nodes. N2: Tumor with metastasis in three to six regional lymph nodes. N3: Tumor with metastasis in seven or more regional lymph nodes. M0: No distant metastasis. M1: Distant metastasis. (AJCC 8th ed.)


name: Nasal Cavity and Paranasal Sinuses Cancer pN3 TNM Finding v8

description: Nasal cavity and paranasal sinuses cancer with metastasis in a lymph node larger than 6 cm in greatest dimension and ENE(-); or metastasis in a single ipsilateral node larger than 3 cm in greatest dimension and ENE(+); or metastases in multiple ipsilateral, contralateral or bilateral nodes, any with ENE(+) . (from AJCC 8th Ed.)


Gastric Cancer cM1 TNM Finding v8

description: Gastric cancer with distant metastasis. (from AJCC 8th Ed.)


Diffuse Midline Glioma

description: A diffuse glioma that arises from the midline structures of the central nervous system. The majority of these tumors are found in the brainstem.


Urethral Cancer pT3 TNM Finding v7

description: Urethral cancer with tumor invading any of the following: corpus cavernosum, beyond prostatic capsule, anterior vagina, bladder neck.  (from AJCC 7th Ed.)


name: Unresectable Gastroesophageal Junction Neuroendocrine Carcinoma

description: A neuroendocrine carcinoma that arises from the gastroesophageal junction and is not amenable to surgical resection.


name: Cerebral Infarction due to Thrombosis Unspecified Middle Cerebral Artery

description: Evidence of cerebral infarction due to a thrombosis of an unspecified middle cerebral artery.


name: Adult Acute Myeloid Leukemia without Maturation

description: An acute myeloid leukemia without maturation occurring in adults.


name: Gravid Uterus Adjusted Maternal Body Weight Gain

description: The amount of maternal body weight gained over a period of time where the weight at the end of the interval is adjusted for the gravid uterus weight. This is derived by subtracting the maternal body weight adjusted for the gravid uterus from the total maternal body weight.


name: Major Salivary Gland Cancer pN2b TNM Finding V8

description: Major salivary gland cancer with metastasis in multiple ipsilateral lymph nodes, none more than 6 cm in greatest dimension and ENE(-).  (from AJCC 8th Ed.)


name: Occlusion and Stenosis of Unspecified Anterior Cerebral Artery

description: Evidence of occlusion and stenosis of unspecified anterior cerebral artery.


name: Breast Cancer pT1a TNM Finding v6 and v7

description: Breast cancer with tumor size more than 0.1 cm, but not more than 0.5 cm in greatest dimension. (from AJCC 6th and 7th Eds.)


name: HER2/Neu Expression by Immunohistochemistry 1+

description: An immunohistochemical result of 1+ for HER2/Neu expression that is considered negative for expression.


Grade 2 Shingles, CTCAE

description: Local infection with moderate symptoms; oral intervention indicated; limiting age-appropriate instrumental ADL


name: Soft Tissue Sarcoma of the Trunk and Extremities pM1 TNM Finding v8

description: Soft tissue sarcoma of the trunk and extremities with distant metastasis. (from AJCC 8th Ed.)


Grade 2 Atrial Fibrillation, CTCAE

description: Non-urgent medical intervention indicated


name: Lip and Oral Cavity Cancer Pathologic Primary Tumor TNM Finding v8

description: A pathologic finding about one or more characteristics of lip and oral cavity cancer, following the rules of the TNM AJCC v8 classification system as they pertain to staging of the primary tumor.


Advanced Angiosarcoma

description: An angiosarcoma that has spread extensively to other anatomic sites or is no longer responding to treatment.


Unresectable Basal Cell Carcinoma

description: Basal cell carcinoma that is not amenable to surgical resection.


name: Exocrine Pancreatic Cancer cM0 TNM Finding v8

description: Exocrine pancreatic cancer without evidence of distant metastasis. (from AJCC 8th Ed.)


anaplastic carcinoma of urethra

description: An undifferentiated carcinoma arising from the urethra.


name: Drug or Chemical Induced Diabetes Mellitus with Proliferative Diabetic Retinopathy with Macular Edema, Unspecified Eye

description: Evidence of drug or chemical induced diabetes mellitus with proliferative diabetic retinopathy with macular edema in an unspecified eye.


Grade 4 Testicular Hemorrhage, CTCAE

description: Life-threatening consequences; urgent intervention indicated


Conjunctival Blue Nevus

description: A benign melanocytic neoplasm that arises from the conjunctiva. It is characterized by the presence of dendritic and spindle-shaped melanocytes in the subepithelial connective tissue. It presents as a dark brown or black, slightly elevated conjunctival lesion.


Intraoperative Endocrine Injury

description: Damage to an endocrine gland during a surgical procedure.


Retinoblastoma pT2a TNM Finding v7

description: Retinoblastoma with tumor superficially invading optic nerve head but not extending past lamina cribrosa or tumor exhibiting focal choroidal invasion. (from AJCC 7th Ed.)


Bilateral anophthalmos of eyes

description: A rare congenital abnormality characterized by the complete absence of ocular tissue in both orbits.


Salivary Gland Fistula, CTCAE

description: A disorder characterized by an abnormal communication between a salivary gland and another organ or anatomic site.


name: acute megakaryoblastic leukemia in relapse

description: The reemergence of acute megakaryoblastic leukemia after a period of remission.


name: Childhood Retinoblastoma by Toronto Guidelines v2 Stage

description: A term that refers to the staging of childhood retinoblastoma according to the Toronto childhood cancer staging guidelines v2.


Decreased Therapeutic Response

description: A reduction in the desirable and beneficial effects resulting from a medical  treatment.


name: Conjunctival Melanoma cTX TNM Finding v8

description: Conjunctival melanoma in which the primary tumor cannot be assessed. (from AJCC 8th Ed.)


name: Grade 4 Nose Infection with Unknown Absolute Neutrophil Count, CTCAE


name: Gastrointestinal Stromal Tumor Clinical Distant Metastasis TNM Finding v8

description: A clinical finding about one or more characteristics of gastrointestinal stromal tumor, following the rules of the TNM AJCC v8 classification system as they pertain to distant metastases.


name: Bladder Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


name: Conjunctival Carcinoma Pathologic TNM Finding v8

description: A pathologic finding about one or more characteristics of conjunctival carcinoma, following the rules of the TNM AJCC v8 classification system.


Grade 1 Esophageal Pain, CTCAE

description: Mild pain


name: Grade 4 Larynx Mucositis or Stomatitis by Clinical Examination Classification, CTCAE


name: Monoplegia of Lower Limb following Non-Traumatic Subarachnoid Hemorrhage Affecting Left Non-Dominant Side

description: Evidence of monoplegia of lower limb following non-traumatic subarachnoid hemorrhage affecting left non-dominant side.


Grade 4 Esophagitis, CTCAE

description: Life-threatening consequences; urgent operative intervention indicated


Localized Lymphoma

description: A lymphoma that is confined to a specific site without evidence of spread to other anatomic sites.


name: Cutaneous Melanoma pM1b(1) TNM Finding v8

description: Cutaneous melanoma with distant metastasis to lung with or without M1a sites of disease. LDH level elevated. (from AJCC 8th Ed.)


malignant enteroglucagonoma

description: A glucagon-producing malignant endocrine neoplasm. It displays vascular invasion and metastasizes to other anatomic sites.


name: Grade 4 Superior Vena Cava Syndrome, CTCAE

description: Life-threatening consequences; urgent multi-modality intervention indicated (e.g., lysis, thrombectomy, surgery)


Subglottic Cancer cM1 TNM Finding v7

description: Subglottic cancer with distant metastasis. (from AJCC 7th Ed.)


name: Other Paralytic Syndrome following Other Cerebrovascular Disease Affecting Unspecified Side

description: Evidence of other paralytic syndrome following other cerebrovascular disease affecting unspecified side not specified elsewhere.


Locally Aggressive Lesion

description: A lesion that is locally destructive despite treatment.


name: Advanced Extrapulmonary Large Cell Neuroendocrine Carcinoma

description: Extrapulmonary large cell neuroendocrine carcinoma that has spread extensively to other anatomic sites or is no longer responding to treatment.


Grade 3 Hoarseness, CTCAE

description: Severe voice changes including predominantly whispered speech


name: Stage III Renal Pelvis and Ureter Cancer AJCC v7

description: Stage III includes: T3, N0, M0. T3: For renal pelvis only: tumor invades beyond muscularis into peripelvic fat or the renal parenchyma.  For ureter only: tumor invades beyond muscularis into periureteric fat.  N0: No regional lymph node metastasis.  M0: No distant metastasis.  (AJCC 7th ed.)


Anal cancer recurrent

description: The reemergence of anal carcinoma after a period of remission.


name: Cytomegalovirus Infection Reactivation, CTCAE

description: A disorder characterized by the reactivation of cytomegalovirus (CMV).


name: Non-Hodgkin Lymphoma, Lymph Nodes of Head, Face, and Neck

description: Evidence of non-Hodgkin lymphoma in the lymph nodes of head, face, and neck.


name: Other Specified Diabetes Mellitus with Other Diabetic Arthropathy

description: Evidence of other specified diabetes mellitus with other diabetic arthropathy not specified elsewhere.


name: Grade 4 Middle Ear Intra-Operative Injury, CTCAE


name: Grade 2 Peritoneal Cavity Infection with Unknown Absolute Neutrophil Count, CTCAE


name: Seasonal Coronavirus Molecular Test Result

description: The outcome of seasonal coronavirus molecular testing.


name: Other Speech and Language Deficits following Unspecified Cerebrovascular Disease

description: Evidence of other speech and language deficits following unspecified cerebrovascular disease not specified elsewhere.


Grade 5 Pneumonitis, CTCAE

description: Death


Grade 4 Enterovesical Fistula, CTCAE

description: Life-threatening consequences; urgent intervention indicated


name: Breast Cancer Clinical Distant Metastasis TNM Finding v6

description: A clinical finding about one or more characteristics of breast cancer, following the rules of the TNM AJCC v6 classification system as they pertain to distant metastases.


name: Pleural Mesothelioma pT1b TNM Finding v7

description: Pleural mesothelioma with a tumor also involving the visceral pleura. (from AJCC 7th Ed.)


name: Renal Pelvis and Ureter Cancer Pathologic Distant Metastasis TNM Finding v8

description: A pathologic finding about one or more characteristics of renal pelvis and ureter cancer, following the rules of the TNM AJCC v8 classification system as they pertain to distant metastases.


name: Leiomyosarcoma and Endometrial Stromal Sarcoma pN1 TNM Finding v7

description: Regional lymph node metastasis. (from AJCC 7th Ed.)


name: Type 2 Diabetes Mellitus with Stable Proliferative Diabetic Retinopathy, Unspecified Eye

description: Evidence of type 2 diabetes mellitus with stable proliferative diabetic retinopathy in an unspecified eye.


name: Leiomyosarcoma and Endometrial Stromal Sarcoma pT2 TNM Finding v7

description: Tumor extends beyond the uterus, within the pelvis. (from AJCC 7th Ed.)


name: Testicular Cancer Clinical Regional Lymph Nodes TNM Finding v8

description: A clinical finding about one or more characteristics of testicular cancer, following the rules of the TNM AJCC v8 classification system as they pertain to staging of regional lymph nodes.


Gender identity disorder

description: A disorder characterized by a strong and persistent cross-gender identification (such as stating a desire to be the other sex or frequently passing as the other sex) coupled with persistent discomfort with his or her sex (manifested in adults, for example, as a preoccupation with altering primary and secondary sex characteristics through hormonal manipulation or surgery).


pT2a TNM Finding

description: A pathologic primary tumor TNM finding. The definition of pT2a finding depends on the particular type of cancer that it refers to; for example, for prostate cancer, pT2a  finding is defined as follows: cancer limited to one-half or less of one lobe of the prostate gland; for lung cancer, pT2a finding is defined as follows: cancer with a tumor size more than 3 cm but 5 cm or less in greatest dimension. (from AJCC 7th Ed.)


Thoracic Meningocele

description: A congenital abnormality in the thoracic region of the spine in which the meninges protrude through a defect in the spinal column.


name: Papillary, Follicular, Hurthle Cell, Poorly Differentiated, and Anaplastic Thyroid Carcinoma pN1a TNM Finding v8

description: Metastasis to level VI or VII (pretracheal, paratracheal, or prelaryngeal/Delphian, or upper mediastinal) lymph nodes. This can be unilateral or bilateral disease. (from AJCC 8th Ed.)


pT4b TNM Finding

description: A pathologic primary tumor TNM finding. The definition of pT4b finding depends on the particular type of cancer that it refers to; for example, for breast cancer, pT4b finding is defined as follows: cancer with ulceration and/or ipsilateral satellite nodules and/or edema (including peau d'orange) of the skin, which do not meet the criteria for inflammatory carcinoma; for gastric cancer, pT4b finding is defined as follows: cancer with tumor invading adjacent structures. (from AJCC 7th Ed.)


name: Grade 3 Gallbladder Infection with Unknown Absolute Neutrophil Count, CTCAE


name: Unresectable Glioneuronal and Neuronal Tumors

description: Glioneuronal and neuronal tumors that are not amenable to surgical resection.


Grade 1 Oral Pain, CTCAE

description: Mild pain


Dysphasia following Cerebral Infarction

description: Evidence of dysphasia following cerebral infarction.


name: Grade 3 Salivary Gland Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


name: Refractory Endometrial Clear Cell Adenocarcinoma

description: Endometrial clear cell adenocarcinoma that is resistant to treatment.


name: Grade 3 Anal or Perianal Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


name: Locally Advanced Extrapulmonary Neuroendocrine Carcinoma

description: Extrapulmonary neuroendocrine carcinoma that has spread from its original site of growth to nearby tissues or lymph nodes.


name: Distal Bile Duct Cancer Pathologic Distant Metastasis TNM Finding v7

description: A pathologic finding about one or more characteristics of distal bile duct cancer, following the rules of the TNM AJCC v7 classification system as they pertain to distant metastases.  There is no pathologic M0 for distal bile duct cancer. (from AJCC 7th Ed.)


name: Grade 5 Anal or Perianal Infection with Unknown Absolute Neutrophil Count, CTCAE


name: Maxillary Sinus Cancer pT2 TNM Finding v6 and v7

description: Maxillary sinus cancer with tumor causing bone erosion or destruction including extension into the hard palate and/or middle nasal meatus, except extension to posterior wall of maxillary sinus and pterygoid plates. (from AJCC 6th and 7th Eds.)


Grade 1 Growth Hormone Abnormal, CTCAE

description: Asymptomatic; clinical or diagnostic observations only; intervention not indicated


name: Sedative, Hypnotic or Anxiolytic Dependence with Sedative, Hypnotic or Anxiolytic-Induced Psychotic Disorder with Delusions

description: Evidence of sedative, hypnotic or anxiolytic dependence with sedative, hypnotic or anxiolytic-induced psychotic disorder with delusions.


Reflux

description: An abnormal backward flow of a body fluid.


Ileal Hemorrhage, CTCAE

description: A disorder characterized by bleeding from the ileal wall.


Infant T Acute Lymphoblastic Leukemia

description: A T-acute lymphoblastic leukemia that occurs in infancy.


Grade 2 Cecal Infection, CTCAE

description: Localized; oral intervention indicated (e.g., antibiotic, antifungal, or antiviral)


Metastatic Urethral Carcinoma

description: A urethral carcinoma that has spread to another anatomical site.


name: Mediastinum Intra-Operative Injury, CTCAE


name: Carcinoma of the Lacrimal Gland Pathologic Primary Tumor TNM Finding v7

description: A pathologic finding about one or more characteristics of carcinoma of the lacrimal gland, following the rules of the TNM AJCC v7 classification system as they pertain to staging of the primary tumor.


name: FIGO Grade 2 Endometrial Endometrioid Adenocarcinoma

description: Endometrial endometrioid adenocarcinoma exhibiting 6-50% solid non-glandular, non-squamous growth.


Mucositis Oral, CTCAE

description: A disorder characterized by ulceration or inflammation of the oral mucosal.


name: Esophagus and Esophagogastric Junction Cancer pT4a TNM Finding v8

description: Esophagus and esophagogastric junction cancer with tumor invading the pleura, pericardium, azygos vein, diaphragm, or peritoneum. (from AJCC 8th Ed.)


Cataract, CTCAE 5.0

description: A disorder characterized by partial or complete opacity of the crystalline lens of one or both eyes. This results in a decrease in visual acuity and eventual blindness if untreated.


5/8 HLA Match

description: Degree of HLA match is 5/8 alleles with fewer than 2 mismatches per locus at HLA-A, -B, -C and -DRB1.


name: Sedative, Hypnotic or Anxiolytic Abuse with Unspecified Disorder

description: Evidence of sedative, hypnotic or anxiolytic abuse with unspecified disorder.


name: Rheumatoid Arthritis with Rheumatoid Factor of Right Hand without Organ or Systems Involvement

description: Evidence of rheumatoid arthritis with rheumatoid factor of right hand without organ or systems involvement.


name: Conjunctival Carcinoma pT4 TNM Finding v8

description: Conjunctival carcinoma with tumor invading the orbit with or without further extension. (from AJCC 8th Ed.)


Other Diseases of Pulmonary Vessels

description: Evidence of other diseases of the pulmonary vessels not specified elsewhere.


name: Beta-2-Microglobulin Greater than 3 g/mL

description: A laboratory test result indicating that beta-2-microglobulin is present in a sample at concentrations exceeding 3 g/mL.


name: Topoisomerase II Inhibitor-Related Acute Myeloid Leukemia

description: Acute myeloid leukemias arising as a result of the mutagenic effect of therapeutic agents targeting DNA-topoisomerase II. The vast majority of patients present without a preceding myelodysplastic phase. The acute myeloid leukemias are usually of the monoblastic or myelomonocytic type. Clonal cytogenetic abnormalities are frequently present and usually involve chromosome 11q23 (MLL gene).


name: Grade 5 Joint Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


Neonatal Fever, AE

description: An adverse event in a newborn characterized by elevation of body temperature above normal due to the production of more heat than the body is able to dissipate.


name: Skin Squamous Cell Carcinoma or Other Skin Carcinomas Pathologic Regional Lymph Nodes TNM Finding v7

description: A pathologic finding about one or more characteristics of skin squamous cell carcinoma or other skin carcinomas, following the rules of the TNM AJCC v7 classification system as they pertain to staging of regional lymph nodes.  The TNM pathologic and clinical regional lymph nodes classifications of skin squamous cell carcinoma or other skin carcinomas are the same. (from AJCC 7th Ed.)


Insomnia, CTCAE 5.0

description: A disorder characterized by difficulty in falling asleep and/or remaining asleep.


name: Malignant Melanoma of Left Ear and External Auricular Canal

description: Evidence of a malignant melanoma of the left ear and external auricular canal.


name: Carcinoma in Situ of Skin of Unspecified Ear and External Auricular Canal

description: Evidence of carcinoma in situ of the skin of unspecified ear and external auricular canal.


Grade 5 Neonatal Bradyarrhythmia, AE

description: A bradyarrhythmia adverse event in a newborn which results in death.


Cervical Cancer pT2b TNM Finding v8

description: Cervical carcinoma invading beyond the uterus but not to the pelvic wall or to lower third of vagina with parametrial invasion. (from AJCC 8th Ed.)


name: Grade 4 Cranial Nerve IV Intra-Operative Injury, CTCAE


Refractory Mucosal Melanoma

description: Mucosal melanoma that is resistant to treatment.


Glucokinase-Associated Hyperinsulinism

description: Hyperinsulinism due to activating mutation(s) in the gene GCK, encoding glucokinase.


name: Other Atherosclerosis of Native Arteries of Extremities, Left Leg

description: Evidence of other atherosclerosis of native arteries of extremities in the left leg not specified elsewhere.


Sarcoma of the Orbit pT4 TNM Finding v7

description: Sarcoma of the orbit with tumor invasion of globe or periorbital structure, such as eyelids, temporal fossa, nasal cavity and paranasal sinuses, and/or central nervous system.  (from AJCC 7th Ed.)


Grade 4 Neonatal Pneumothorax, AE

description: A pneumothorax adverse event in a newborn characterized by life-threatening respiratory and/or hemodynamic compromise (e.g. tension pneumothorax); urgent major care change required.


Childhood Grade I Meningioma

description: A grade I meningioma that occurs during childhood.


Grade 4 Rectal Ulcer, CTCAE

description: Life-threatening consequences; urgent operative intervention indicated


Grade 1 Accessory Nerve Disorder, CTCAE

description: Asymptomatic; clinical or diagnostic observations only; intervention not indicated


Pelvic Pain, CTCAE 5.0

description: A disorder characterized by a sensation of marked discomfort in the pelvis.


name: Adverse Event Associated with Sexual and Reproductive Function


name: Rheumatoid Polyneuropathy with Rheumatoid Arthritis of Right Hip

description: Evidence of rheumatoid polyneuropathy with rheumatoid arthritis of right hip.


name: Chronic respiratory conditions due to chemicals, gases, fumes and vapors

description: Evidence of chronic respiratory condition due to chemicals, gases, fumes and vapors.


Regional Tumor Implant

description: Tumor implant developed regionally to the primary site of cancer.


name: Grade 1 Blood Gonadotrophin Abnormal, CTCAE


name: Merkel Cell Carcinoma of Right Ear and External Auricular Canal

description: Evidence of Merkel cell carcinoma of right ear and external auricular canal.


name: Malignant Neoplasm of Post-Cricoid Region

description: Evidence of a malignant neoplasm of the post-cricoid region.


Cervical Cancer pT2a TNM Finding v9

description: Cervical carcinoma with involvement limited to the upper two-thirds of the vagina without parametrial invasion. (from AJCC 9th Ed.)


name: Serum Glutamic Oxaloacetic Transaminase, CTCAE


Grade 4 Cervicitis Infection, CTCAE

description: Life-threatening consequences; urgent intervention indicated


name: Grade 2 Associated with the Teeth, CTCAE


name: Type 2 Diabetes Mellitus with Other Diabetic Ophthalmic Complication

description: Evidence of type 2 diabetes mellitus with other diabetic ophthalmic complication.


Grade 3 Duodenal Perforation, CTCAE

description: Invasive intervention indicated


Grade 3 Serum Amylase Increased, CTCAE

description: >2.0-5.0 x ULN with signs or symptoms; >5.0 x ULN and asymptomatic


name: Rheumatoid Arthritis of Right Knee with Involvement of Organs and Systems

description: Evidence of rheumatoid arthritis of right knee with involvement of organs and systems.


name: Renal Pelvis and Ureter Cancer pM1 TNM Finding v8

description: Renal pelvis and ureter cancer with distant metastasis. (from AJCC 8th Ed.)


name: atherosclerosis of other type of bypass graft of right leg with ulceration of heel and midfoot

description: Evidence of atherosclerosis of other type of bypass graft(s) of right leg with ulceration of heel and midfoot.


Serum Bicarbonate Decreased

description: A laboratory test result which indicates decreased levels of bicarbonate in the serum.


name: Stage 0 Childhood Retinoblastoma by Toronto Guidelines v2

description: The tumor is confined to the globe. Enucleation has not been performed. (The patient is treated "conservatively" with either focal therapies or chemotherapy.) (Childhood cancer staging for population registries according to the Toronto Childhood Cancer Stage Guidelines - Version 2. Cancer Council Queensland and Cancer Australia: Brisbane, Australia; 2021.)


Gastric Cancer pT4 TNM Finding v6

description: Gastric cancer with tumor invading into adjacent structures of the stomach which include the spleen, transverse colon, liver, diaphragm, pancreas, abdominal wall, adrenal gland, kidney, small intestine, and retroperitoneum. Intramural extension into the esophagus or duodenum is classified by the depth of the greatest invasion in any of these sites, including the stomach. (from AJCC 6th Ed.)


name: Merkel Cell Carcinoma cM1 TNM Finding v8

description: Merkel cell carcinoma with distant metastasis detected on clinical and/or radiologic examination. (from AJCC 8th Ed.)


Grade 2 Bloating, CTCAE

description: Symptomatic, decreased oral intake; change in bowel function


description: Evidence of mast cell leukemia not having achieved remission.


name: Small Intestine Cancer pT1a TNM Finding v7

description: Small intestine cancer with tumor invading lamina propria.  (from AJCC 7th Ed.)


Cross-Patient Exposure to Body Fluids

description: The patient becomes contaminated from contact with blood/fluids on a device.


Atherosclerosis of other arteries

description: Evidence of atherosclerosis of other arteries.


name: Grade 3 Small Bowel Infection NOS Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


name: Grade 4 Larynx Intra-Operative Injury, CTCAE


name: Carcinoma of the Lacrimal Gland cM0 TNM Finding v7

description: Carcinoma of the lacrimal gland without evidence of distant metastasis. (from AJCC 7th Ed.)


name: Duodenum and Ampulla of Vater Neuroendocrine Tumor pT2 TNM Finding v8

description: Duodenum neuroendocrine tumor invading the muscularis propria or measuring more than 1 cm; Ampulla of Vater neuroendocrine tumor invading through the sphincter of Oddi into duodenal submucosa or muscularis propria, or measuring more than 1 cm. (from AJCC 8th Ed.)


Childhood Astroblastoma, MN1-Altered

description: An astroblastoma, MN1-altered that occurs during childhood.


name: Exocrine Pancreatic Cancer pT1b TNM Finding v8

description: Exocrine pancreatic cancer with tumor measuring more than 0.5 cm and less than 1 cm in greatest dimension. (from AJCC 8th Ed.)


Stage IIIA Prostate Cancer AJCC v8

description: Stage IIIA includes: T1-2, N0, M0, PSA 20 or more, Grade Group 1-4; T1: Prostate cancer with clinically inapparent tumor that is not palpable. T2: Prostate cancer in which the tumor is palpable and confined within the prostate. N0: Prostate cancer with no positive regional nodes. M0: Prostate cancer without evidence of distant metastasis. Grade Group 1: Gleason Score 6 or less, Gleason Pattern 3 or less+3. Grade Group 2: Gleason Score 7, Gleason Pattern 3+4. Grade Group 3: Gleason Score 7, Gleason Pattern 4+3. Grade Group 4: Gleason Score 8, Gleason Pattern 4+4. (AJCC 8th ed.)


name: Invasive Bladder Conventional Urothelial Carcinoma

description: Invasive bladder urothelial carcinoma characterized by the presence of malignant cells forming trabeculae, cords, sheets, and nests. Individual malignant cells are also present.


Urethral Cancer pT2 TNM Finding v7

description: Urethral cancer with tumor invading any of the following: corpus spongiosum, prostate, periurethral muscle.  (from AJCC 7th Ed.)


name: Drug or Chemical Induced Diabetes Mellitus with Proliferative Diabetic Retinopathy without Macular Edema, Unspecified Eye

description: Evidence of drug or chemical induced diabetes mellitus with proliferative diabetic retinopathy without macular edema in an unspecified eye.


Grade 2 Nystagmus, CTCAE

description: Moderate symptoms; limiting instrumental ADL


name: Rheumatoid Heart Disease with Rheumatoid Arthritis of Unspecified Wrist

description: Evidence of rheumatoid heart disease with rheumatoid arthritis of unspecified wrist.


name: Pelvis Cancer Pathologic Primary Tumor TNM Finding v8

description: A pathologic finding about one or more characteristics of pelvis cancer, following the rules of the TNM AJCC v8 classification system as they pertain to staging of the primary tumor.


FNCLCC Sarcoma Grade 1

description: A sarcoma with a total score of 2 or 3 according to the FNCLCC guidelines.


Refluxing Megaureter

description: A megaureter that demonstrates retrograde urine flow without ureteral obstruction.


Grade 5 Photosensitivity, CTCAE

description: Death


name: Grade 3 Foreign Body Infection with Unknown Absolute Neutrophil Count, CTCAE


name: Choroidal and Ciliary Body Melanoma pT3d TNM Finding v8

description: Choroidal and ciliary body melanoma, tumor size category 3 with ciliary body involvement and extraocular extension 5 mm or less in largest diameter. (from AJCC 8th Ed.)


name: Grade 2 Prolapse of Intestinal Stoma, CTCAE

description: Recurrent after manual reduction; local irritation or stool leakage; difficulty to fit appliance; limiting instrumental ADL


Grade 2 Periorbital Infection, CTCAE

description: Localized; local intervention indicated (e.g., topical antibiotic, antifungal, or antiviral)


name: Other Specified Diabetes Mellitus with Proliferative Diabetic Retinopathy with Macular Edema, Left Eye

description: Evidence of other specified diabetes mellitus with proliferative diabetic retinopathy with macular edema in the left eye not specified elsewhere.


name: Grade 4 Small Bowel Obstruction NOS, CTCAE


name: Grade 3 Bladder Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


Meningothelial Hamartoma

description: A hamartoma characterized by the presence of collections of non-neoplastic arachnoidal cells.


name: Malignant urinary tract neoplasm metastatic

description: The spread of a malignant neoplasm to the urinary tract from an adjacent or distant anatomic site.


Prolonged QTc Interval, CTCAE

description: An adverse event characterized by an abnormally long interval between the start of the Q wave and the end of the T wave in the heart's electrical cycle, corrected for heart rate.


Supraglottic Cancer pTis TNM Finding v8

description: Supraglottic cancer with a finding of carcinoma in situ. (from AJCC 8th Ed.)


name: Grade 3 Prolonged Chest Tube Drainage or Air Leak After Pulmonary Resection, CTCAE


Breast Cancer pT2 TNM Finding v6 and v7

description: Breast cancer with tumor size more than 2.0 cm, but not more than 5.0 cm in greatest dimension. (from AJCC 6th and 7th Eds.)


Grade 1 Neonatal Pneumothorax, AE

description: An adverse event in a newborn characterized by radiological evidence of pneumothorax; no clinical signs; no care change required.


Grade 5 Joint Infection, CTCAE

description: Death


name: Occlusion and stenosis of other cerebral artery

description: Evidence of occlusion and stenosis of other cerebral arteries.


Grade 4 Death Neonatal, CTCAE

description: Neonatal loss of life


name: adenocarcinoma of gallbladder with squamous metaplasia

description: An infiltrating adenocarcinoma of the gallbladder characterized by the presence of metaplastic changes of the malignant glandular cells to squamous cells.


name: Epileptic Spasms, not Intractable, without Status Epilepticus

description: Evidence of epileptic spasms without status epilepticus that responds to treatment.


name: Grade 3 Adult Respiratory Distress Syndrome, CTCAE

description: Present with radiologic findings; intubation not indicated


T1a2 Stage Finding

description: A general term that refers to a TNM finding of a primary tumor limited to the site of growth. The definition of T1a2 TNM finding depends on the specific type of cancer to which it refers: for example, for cervical carcinoma it indicates measured stromal invasion of more than 3.0 mm and equal or less than 5.0 mm in depth.


Hodgkin Lymphoma by Ann Arbor Stage

description: An anatomic stage for Hodgkin lymphomas based on the Ann Arbor classification criteria.


Complicated malaria

description: Acute malaria with signs of organ dysfunction, severe anemia (hemoglobin less than 5 g/dL or hematocrit less than 15%) and/or hyperparasitemia (greater than 5% of red blood cells infected).


name: Cervical Cancer Pathologic Primary Tumor TNM Finding v8

description: A pathologic finding about one or more characteristics of cervical cancer, following the rules of the TNM AJCC v8 classification system as they pertain to staging of the primary tumor.


Cervical Cancer cTX TNM Finding v7

description: Cervical cancer in which primary tumor cannot be assessed. (from AJCC 7th Ed.)


name: Major Salivary Gland Cancer Pathologic Distant Metastasis TNM Finding v7

description: A pathologic finding about one or more characteristics of major salivary gland cancer, following the rules of the TNM AJCC v7 classification system as they pertain to distant metastases.  There is no pathologic M0 for major salivary gland cancer.


name: Atherosclerosis of Native Arteries of Extremity with Rest Pain, Other Extremity

description: Evidence of atherosclerosis of native arteries of extremity with rest pain, in the other extremity.


name: Papillary transitional cell carcinoma, non-invasive

description: A transitional cell carcinoma characterized by a papillary growth pattern and lack of stromal invasion.


name: Non-Keratinizing Primary Intraosseous Squamous Cell Carcinoma -Solid Type

description: A squamous cell carcinoma that arises centrally from the jaw.  It is characterized by a solid pattern, lack of prominent keratinization, infiltration of the marrow spaces, and osseous resorption.


name: Lip and Oral Cavity Cancer pTX TNM Finding v8

description: Lip and oral cavity cancer in which the primary tumor cannot be assessed. (from AJCC 8th Ed.)


Oropharyngeal Cancer pN2 TNM Finding v7

description: Oropharyngeal cancer with metastasis in a single ipsilateral lymph node, more than 3 cm but not more than 6 cm in greatest dimension, or in multiple ipsilateral lymph nodes, none more than 6 cm in greatest dimension, or in bilateral or contralateral lymph nodes, none more than 6 cm in greatest dimension. (from AJCC 7th Ed.)


name: Embolism and Thrombosis of Unspecified Parts of Aorta

description: Evidence of embolism and thrombosis of unspecified parts of aorta.


name: Rheumatoid Lung Disease with Rheumatoid Arthritis of Unspecified Wrist

description: Evidence of rheumatoid lung disease with rheumatoid arthritis of unspecified wrist.


name: Unspecified Atherosclerosis of Autologous Vein Bypass Graft(s) of the Extremities, Other Extremity

description: Evidence of unspecified atherosclerosis of autologous vein bypass graft(s) of the extremities, in the other extremity.


Decreased Secretion

description: Decrease in the amount of a secretory content present in the glandular lumen.


Notched Nodule

description: Single clear indentation of the nodule surface, resulting in a smooth or sharp concavity along the nodule margin (usually distinguished from lobulated by the fact there is one predominant indentation and the concavity is greater than or equal to 3 mm.


name: Grade 3 Encephalomyelitis Infection, CTCAE

description: IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated


name: High Grade Prostatic Intraepithelial Neoplasia, Inverted Variant

description: High grade prostatic intraepithelial neoplasia characterized by the presence of secretory cells with their nuclei polarized towards the lumen of the glands.


PSA Level Less than Fifteen

description: A blood concentration of prostate specific antigen less than 15 ng/mL.


name: Grade 3 Peristomal Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


name: other non-follicular lymphoma, extranodal and solid organ sites

description: Evidence of other non-follicular lymphoma in the extranodal and solid organ sites not specified elsewhere.


name: Gallbladder Intra-Operative Injury, CTCAE


Pelvis Cancer pT2a TNM Finding v8

description: Pelvis cancer with tumor confined to one pelvic segment with extraosseous extension or two segments without extraosseous extension and measuring 8 cm or less in greatest dimension. (from AJCC 8th Ed.)


Non-Neoplastic Conjunctival Disorder

description: A non-neoplastic disorder that affects the conjunctiva.


Unresectable Bladder Carcinoma

description: Bladder carcinoma that is not amenable to surgical resection.


name: Sezary's disease involving lymph nodes of head, face, and neck

description: Evidence of Sezary disease in the lymph nodes of head, face and neck.


Sensitizing EGFR Mutation Negative

description: A finding indicating that mutations in the EGFR gene that impart increased sensitivity to EGFR inhibitory agents were not detected in a sample.


name: Other Rheumatoid Arthritis with Rheumatoid Factor of Left Elbow

description: Evidence of other rheumatoid arthritis with rheumatoid factor of left elbow not specified elsewhere.


name: Grade 3 Psychiatric Disorders - Other, Specify, CTCAE

description: Severe or medically significant but not immediately life-threatening; limiting self care ADL


name: Intrahepatic Bile Duct Cancer pM1 TNM Finding v7

description: Intrahepatic bile duct cancer with distant metastasis. (from AJCC 7th Ed.)


name: Stage I Adult Diffuse Small Cleaved Cell Lymphoma

description: Stage I: Involvement of a single lymph node region (I) or localized involvement of a single extralymphatic organ or site (IE). (from PDQ)


name: HER2/Neu Status by Validated Dual-probe in Situ Hybridization

description: An in situ hybridization assay for HER2/Neu that combines a validated assay for HER2 with a probe for chromosome 17, with the assay performed in a validated testing lab.


Minimal Response of Multiple Myeloma

description: Patients in whom some, but not all, the criteria for partial response are fulfilled are classified as minimal response (MR), provided the remaining criteria satisfy the requirements for minimal response.  MR requires all of the following: 1. 25-49% reduction in the level of the serum monoclonal paraprotein maintained for a minimum of 6 weeks; 2. 50-89% reduction in 24 h urinary light chain excretion, which still exceeds 200 mg/24 h, maintained for a minimum of 6 weeks; 3. for patients with non-secretory myeloma only, 25-49% reduction in plasma cells in a bone marrow aspirate and on trephine biopsy, if biopsy is performed, maintained for a minimum of 6 weeks; 4. 25-49% reduction in the size of soft tissue plasmacytomas (by radiography or clinical examination); 5. no increase in size or number of lytic bone lesions (development of a compression fracture does not exclude response) (adapted from National Comprehensive Cancer Network).


Stage IV Prostate Cancer AJCC v7

description: Stage IV includes: (T4, N0, M0, Any PSA, Any Gleason); (Any T, N1, M0, Any PSA, Any Gleason); (Any T, Any N, M1, Any PSA, Any Gleason). cT4: Tumor is fixed or invades adjacent structures other than seminal vesicles such as external sphincter, rectum, bladder, levator muscles, and/or pelvic wall.  pT4: Invasion of rectum, levator muscles, and/or pelvic wall.  N1: Metastasis in regional lymph node(s).  M1: Distant metastasis.  (AJCC 7th ed.)


name: Monoplegia of Upper Limb following Other Cerebrovascular Disease Affecting Right Dominant Side

description: Evidence of monoplegia of upper limb following other cerebrovascular disease affecting right dominant side.


Ileal Fistula, CTCAE

description: A disorder characterized by an abnormal communication between the ileum and another organ or anatomic site.


Sinus Disorder, CTCAE

description: A disorder characterized by involvement of the paranasal sinuses.


name: Diffuse Low Grade Glioma, BRAF p.V600E-Mutant

description: Diffuse low-grade glioma characterized by the presence of BRAF gene mutations encoding a p.V600E substitution mutation.


name: Grade 5 Colon or Cecum or Appendix Fistula, CTCAE


name: Pathologic Stage IIIB Cutaneous Melanoma AJCC v8

description: Stage IIIB includes: (T0, N1b, N1c, M0); (T1a/b-T2a, N1b/c or N2b, M0); (T2b/T3a, N1a-N2b, M0). T0: No evidence of primary tumor (e.g., unknown primary or completely regressed melanoma). Thickness: Not applicable. Ulceration status: Not applicable. T1a: Tumor measuring less than 0.8 mm in thickness. Ulceration status: Without ulceration. T1b: Tumor measuring less than 0.8 mm in thickness with ulceration, or 0.8-1.0 mm with or without ulceration. T2a: Tumor measuring more than 1.0 and equal to or less than 2.0 mm in thickness. Ulceration status: Without ulceration.  T2b: Tumor measuring more than 1.0 and equal to or less than 2.0 mm in thickness. Ulceration status: With ulceration. T3a: Tumor measuring more than 2.0 and equal to or less than 4.0 mm in thickness. Ulceration status: Without ulceration. N1b: One clinically detected nodal metastasis. Presence of in-transit, satellite, and/or microsatellite metastases: No. N1c: No regional lymph node disease. Presence of in-transit, satellite, and/or microsatellite metastases: Yes. N2b: Two or three nodal metastases at least one of which was clinically detected. Presence of in-transit, satellite, and/or microsatellite metastases: No. N1a: One clinically occult nodal metastasis (i.e., detected by sentinel lymph node biopsy). Presence of in-transit, satellite, and/or microsatellite metastases: No. N2a: Two or three clinically occult nodal metastases (i.e., detected by sentinel lymph node biopsy). Presence of in-transit, satellite, and/or microsatellite metastases: No. M0: No evidence of distant metastasis. LDH level is not applicable. (AJCC 8th ed.)


name: Grade 3 Lung Thoracic Nerve Intra-Operative Injury, CTCAE


pN2 TNM Finding

description: A pathologic regional lymph nodes TNM finding. The definition of pN2 finding depends on the particular type of cancer that it refers to; for example, for breast cancer, pN2 finding is defined as follows: cancer with metastases in 4 to 9 axillary lymph nodes, or metastases in clinically detected internal mammary lymph nodes in the absence of axillary lymph node metastases. "Clinically detected" is defined as detected by imaging studies (excluding lymphoscintigraphy) or by clinical examination and having characteristics highly suspicious for malignancy or a presumed pathologic macrometastasis based on fine needle aspiration biopsy with cytologic examination; for colorectal cancer, pN2 stage finding is defined as follows: cancer with metastasis in four or more regional lymph nodes. (from AJCC 7th Ed.)


Recurrent Brain Neoplasm

description: The reemergence of a brain neoplasm after a period of remission.


description: A myelodysplastic/myeloproliferative neoplasm that is resistant to treatment.


Prostate Cancer pM0 TNM Finding

description: Prostate cancer with no evidence of distant metastasis. (from AJCC 6th Ed.)


Grade 2 Productive Cough, CTCAE

description: Moderate sputum production; limiting instrumental ADL


Chemical Exposure

description: Contact with a chemical substance through touch, inhalation, or ingestion.


name: Maxillary Sinus Cancer pT1 TNM Finding v8

description: Maxillary sinus cancer with tumor limited to the maxillary sinus mucosa with no erosion or destruction of bone. (from AJCC 8th Ed.)


Radiation-Induced Cancer

description: A malignant neoplasm arising in a site exposed to radiation therapy.


name: Carbon Monoxide Diffusion Capacity, CTCAE


name: Grade 1 Oral Cavity Mucositis or Stomatitis by Clinical Examination Classification, CTCAE


name: Drug or Chemical Induced Diabetes Mellitus with Stable Proliferative Diabetic Retinopathy, Bilateral

description: Evidence of drug or chemical induced diabetes mellitus with stable proliferative diabetic retinopathy that is bilateral.


Vulvar Blue Nevus

description: A benign nevus that arises from the vulva and is characterized by the presence of heavily pigmented dendritic melanocytes exclusively in the dermis.


name: Grade 2 Pelvis Infection NOS with Unknown Absolute Neutrophil Count, CTCAE


Kidney Cancer Pathologic TNM Finding v6

description: A pathologic finding about one or more characteristics of kidney cancer, following the rules of the TNM AJCC v6 classification system.


name: Paranasal Infection with Unknown Absolute Neutrophil Count, CTCAE


name: Appendicular Skeleton, Trunk, Skull, and Facial Bones Cancer pT2 TNM Finding v8

description: Appendicular skeleton, trunk, skull, and facial bones cancer with tumor measuring more than 8 cm in greatest dimension. (from AJCC 8th Ed.)


name: chronic total atherosclerotic occlusion of artery of extremities

description: Evidence of chronic total occlusion of artery of the extremities.


Non-Malignant Neoplasm

description: A category that includes benign neoplasms and neoplasms with uncertain malignant potential. The latter are characterized by clinicopathological features that are not benign, including some degree of mild or mild/moderate atypia/dysplasia, but lack overt malignant morphologic characteristics and there is no evidence of metastasis at the time of diagnosis.


Edema Face, CTCAE

description: A disorder characterized by swelling due to excessive fluid accumulation in facial tissues.


Grade 2 Rash Acneiform, CTCAE

description: Papules and/or pustules covering 10-30% BSA, which may or may not be associated with symptoms of pruritus or tenderness; associated with psychosocial impact; limiting instrumental ADL; papules and/or pustules covering > 30% BSA with or without mild symptoms


Gonadal Thrombosis

description: Formation of a blood clot (thrombus) in the lumen of the vein that carries blood away from the testis or ovary.


name: Grade 2 Duodenum Infection with Unknown Absolute Neutrophil Count, CTCAE


name: Cerebral Infarction To Thrombosis of Bilateral Cerebellar Arteries

description: Evidence of cerebral infarction to thrombosis of bilateral cerebellar arteries.


name: Localization-Related Idiopathic Epilepsy and Epileptic Syndromes with Seizures of Localized Onset, not Intractable, without Status Epilepticus

description: Evidence of localization-related idiopathic epilepsy and epileptic syndromes with seizures of localized onset without status epilepticus that responds to treatment.


name: Grade 1 Endocrine Disorders - Other, Specify, CTCAE

description: Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated


Retinoblastoma cT2b TNM Finding v7

description: Massive vitreous and/or subretinal seeding is present, defined as diffuse clumps or "snowballs" of tumor cells. (from AJCC 7th Ed.)


name: Grade 4 Trachea Mucositis or Stomatitis by Functional or Symptomatic Classification, CTCAE


name: Gastric carcinoma stage IV without metastases

description: T4,N2,MO (from PDQ)


name: Grade 4 Pharynx Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


Anorexia, CTCAE

description: A disorder characterized by a loss of appetite.


Therapy-Related Toxicity

description: The finding of bodily harm due to the poisonous effects associated with the action or administration of therapeutic agents.


name: Ocular Adnexal Lymphoma Pathologic Primary Tumor TNM Finding v7

description: A pathologic finding about one or more characteristics of ocular adnexal lymphoma, following the rules of the TNM AJCC v7 classification system as they pertain to staging of the primary tumor.


name: Grade 5 External Ear Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


name: Grade 4 Soft Tissue Infection NOS Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


Myelitis, CTCAE

description: A disorder characterized by inflammation involving the spinal cord. Symptoms include weakness, paresthesia, sensory loss, marked discomfort and incontinence.


name: Diabetes Mellitus due to Underlying Condition with Proliferative Diabetic Retinopathy with Macular Edema, Left Eye

description: Evidence of diabetes mellitus due to underlying condition with proliferative diabetic retinopathy with macular edema in the left eye.


name: Malignant Neoplasm of Left Broad Ligament

description: Evidence of a malignant neoplasm of the left broad ligament.


Stage IIIB Testicular Cancer AJCC v8

description: Stage IIIB includes: (Any pT/TX, N1-3, M0, S2); (Any pT/TX, Any N, M1a, S2). TX: Testicular cancer in which the primary tumor cannot be assessed. N1: Testicular cancer with metastasis with a lymph node mass 2 cm or smaller in greatest dimension and less than or equal to five nodes positive, none larger than 2 cm in greatest dimension. N2: Testicular cancer with metastasis with a lymph node mass larger than 2 cm but not larger than 5 cm in greatest dimension; or more than five nodes positive, none larger than 5 cm; or evidence of extranodal extension of tumor. N3: Testicular cancer with metastasis with a lymph node mass larger than 5 cm in greatest dimension. M0: Testicular cancer without evidence of distant metastasis. M1a: Testicular cancer with non-retroperitoneal nodal or pulmonary metastases. S2: LDH 1.5-10 x N or hCG (mlU/mL) 5,000-50,000 or AFP (ng/mL) 1,000-10,000. N indicates the upper limit of normal for the LDH assay. (AJCC 8th ed.)


name: Gastric Neuroendocrine Tumor pT2 TNM Finding v7

description: Gastric neuroendocrine tumor invading muscularis propria or is more than 1 cm in size. (from AJCC 7th Ed.)


name: External Ear Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


name: Cannabis Dependence with Unspecified Cannabis-Induced Disorder

description: Evidence of cannabis dependence with unspecified cannabis-induced disorder.


Grade 3 Endocarditis Infective, CTCAE

description: IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated


Goblet Cell Adenocarcinoma

description: A rare adenocarcinoma that exhibits neuroendocrine differentiation and is associated with the presence of neoplastic signet-ring cells resembling goblet cells of the intestine.


Grade 2 Esophageal Obstruction, CTCAE

description: Symptomatic; altered GI function; limiting instrumental ADL


Transplant-Related Carcinoma

description: A carcinoma that arises in a patient with a history of organ transplantation.


Stage IA2 Cervical Cancer AJCC v9

description: Stage IA2 includes: T1a2, N0, M0. T1a2: Tumor with measured stromal invasion of more than 3.0 mm and equal or less than 5.0 mm in depth. N0: No regional lymph node metastasis. M0: No distant metastasis. (from AJCC 9th Ed.)


name: Atherosclerosis of Native Arteries of the Extremities with Gangrene, Other Extremity

description: Evidence of atherosclerosis of native arteries of the extremities with gangrene, in the other extremity.


Duodenal fistula

description: An abnormal communication between the duodenum and another organ or cavity.


Stage I Gallbladder Cancer AJCC v8

description: Stage I includes: T1, N0, M0. T1: Tumor invading the lamina propria or muscular layer. N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 8th ed.)


Hyperinsulinemia

description: Abnormally high levels of insulin in the blood.