description: A subtype of myelodysplastic syndrome which initially lacks findings appropriate for classification into any other myelodysplastic category.  There are no specific morphologic findings.  The diagnosis can be made in the following instances: 1. in cases of refractory cytopenia with unilineage dysplasia or refractory cytopenia with multilineage dysplasia but with 1% blasts in the peripheral blood; 2: in cases of myelodysplastic syndrome with unilineage dysplasia which are associated with pancytopenia; 3: in cases with persistent cytopenia (s) with 1% or fewer blasts in the blood and fewer than 5% in the bone marrow, unequivocal dysplasia in less than 10% of the cells in one or more myeloid lineages, and cytogenetic abnormalities considered as presumptive evidence of myelodysplastic syndrome. (WHO, 2008)


name: Parathyroid Carcinoma Pathologic Primary Tumor TNM Finding v8

category: biolink:PhenotypicFeature biolink:DiseaseOrPhenotypicFeature biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing

description: A pathologic finding about one or more characteristics of parathyroid carcinoma, following the rules of the TNM AJCC v8 classification system as they pertain to staging of the primary tumor.


Grade 2 Pancreatic Duct Stenosis, CTCAE

description: Symptomatic; altered GI function


Stage IVA Prostate Cancer AJCC v8

category: biolink:Disease biolink:DiseaseOrPhenotypicFeature biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing

description: Stage IVA includes: Any T, N1, M0, PSA: Any, Grade Group: Any. N1: Prostate cancer with metastases in regional node(s). M0: Prostate cancer without evidence of distant metastasis. (AJCC 8th ed.)


Appendiceal Carcinoma TNM Finding v8

description: A finding about one or more characteristics of appendiceal carcinoma, following the rules of the TNM AJCC v8 classification system. This staging system applies to carcinomas of the appendix, including high-grade neuroendocrine carcinomas, mixed adenoneuroendocrine carcinomas, and goblet cell carcinoids. Well-differentiated neuroendocrine tumors (carcinoids) are staged according to the classification for neuroendocrine tumors of the appendix. (from AJCC 8th Ed.)


name: Stage 0 Digestive System Neuroendocrine Tumor AJCC v7

description: Stage 0 includes: Tis, N0, M0.  Tis (applies only to stomach): Carcinoma in situ/dysplasia (tumor size less than 0.5 mm), confined to mucosa. N0: No regional lymph node metastasis.  M0: No distant metastasis. (AJCC 7th ed.)


name: Nasopharyngeal Cancer pM1 TNM Finding v8

description: Nasopharyngeal cancer with distant metastasis. (from AJCC 8th Ed.)


name: Exocrine Pancreatic Cancer Pathologic Distant Metastasis TNM Finding v8

description: A pathologic finding about one or more characteristics of exocrine pancreatic cancer, following the rules of the TNM AJCC v8 classification system as they pertain to distant metastases.


name: Type 1 Diabetes Mellitus with Mild Nonproliferative Diabetic Retinopathy with Macular Edema, Unspecified Eye

description: Evidence of type 1 diabetes mellitus with mild nonproliferative diabetic retinopathy with macular edema in an unspecified eye.


Juvenile Dermatomyositis Sine Myositis

description: A rare form of juvenile dermatomyositis that manifests with characteristic cutaneous findings for at least six months in the absence of any detectable muscle involvement.


Sarcoma of the Orbit pN0 TNM Finding v7

description: Sarcoma of the orbit with no regional lymph node metastasis. (from AJCC 7th Ed.)


Advanced Cutaneous Melanoma

description: Cutaneous melanoma that has spread extensively to other anatomic sites or is no longer responding to treatment.


Follicular Lymphoma Grade I, Spleen

description: Evidence of follicular lymphoma grade I in the spleen.


Non-Metastatic Mass

description: A benign or malignant solid pathologic process that has not spread from its site of origin to another anatomic site.


Grade 3 Enterovesical Fistula, CTCAE

description: Invasive intervention indicated


Iris Melanoma pT1b TNM Finding v8

description: Iris melanoma with tumor limited to the iris, more than 3 clock hours in size. (from AJCC 8th Ed.)


name: Grade 3 Teeth Intra-Operative Injury, CTCAE


Pleural Mesothelioma pT3 TNM Finding v7

description: Pleural mesothelioma with a locally advanced but potentially respectable tumor.  Tumor involving all the ipsilateral pleural surfaces (parietal, mediastinal, diaphragmatic, and visceral pleura) with at least one of the following: involvement of the endothoracic fascia; extension into the mediastinal fat; solitary, completely respectable focus of tumor extending into the soft tissues of the chest wall; nontransmural involvement of the pericardium. (from AJCC 7th Ed.)


name: Grade 1 Blood Antidiuretic Hormone Abnormal, CTCAE

description: Asymptomatic; clinical or diagnostic observations only; intervention not indicated


Metastatic malignant neoplasm to brain

description: A malignant neoplasm that has spread to the brain from another anatomic site or system. The majority are carcinomas (usually lung or breast carcinomas).


Breast Cancer pT3 TNM Finding v8

description: Breast cancer with tumor size more than 50 mm in greatest dimension. (from AJCC 8th Ed.)


Vulvar Cancer pT1b TNM Finding v8

description: Vulvar cancer with lesion measuring more than 2 cm, or any size with stromal invasion of more than 1.0 mm, confined to the vulva and/or perineum. (from AJCC 8th Ed.)


secondary carcinoid tumor of peritoneum

description: Evidence of secondary carcinoid tumors of peritoneum.


name: acute monoblastic/monocytic leukemia not having achieved remission

description: Evidence of acute monoblastic and monocytic leukemia not having achieved remission.


Bladder Cancer Clinical TNM Finding v7

description: A clinical finding about one or more characteristics of bladder cancer, following the rules of the TNM AJCC v7 classification system.  Primary tumor assessment includes bimanual examination under anesthesia before and after endoscopic surgery (biopsy or transurethral resection) and histologic verification of the presence or absence of tumor when indicated.  Appropriate imaging techniques for extravesical extension of the primary tumor and lymph node evaluation should be incorporated into clinical staging. (from AJCC 7th Ed.)


name: Stage IIA Ampulla of Vater Cancer AJCC v7

description: Stage IIA includes: T3, N0, M0.  T3: Tumor invades the pancreas.  N0: No regional lymph node metastasis.  M0: No distant metastasis. (from AJCC 7th Ed.)


Grade 4 Anal Hemorrhage, CTCAE

description: Life-threatening consequences; urgent intervention indicated


Grade 5 Budd-Chiari Syndrome, CTCAE

description: Death


name: Grade 1 Radiation Recall Reaction (Dermatologic), CTCAE

description: Faint erythema or dry desquamation


Sarcoma of the Orbit pTX TNM Finding v7

description: Sarcoma of the orbit in which the primary tumor cannot be assessed. (from AJCC 7th Ed.)


name: Grade 3 Neoplasms Benign, Malignant and Unspecified (Incl Cysts and Polyps) - Other, Specify, CTCAE

description: Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL


Refractory Myelofibrosis

description: Myelofibrosis that is resistant to treatment.


Grade 5 Somnolence, CTCAE

description: Death


name: Grade 2 Pancreas or Pancreatic Duct Stricture or Stenosis, CTCAE


Fetal Growth Retardation, CTCAE

description: A disorder characterized by inhibition of fetal growth resulting in the inability of the fetus to achieve its potential weight.


name: Childhood Acute Lymphoblastic Leukemia Toronto Guidelines v2, Tier 1

description: A term that refers to the staging of childhood acute lymphoblastic leukemia according to the tier 1 Toronto childhood cancer staging guidelines v2.


Gastric Cancer pN3a TNM Finding v7

description: Gastric cancer with metastasis in 7-15 regional lymph nodes. (from AJCC 7th Ed.)


name: Hallucinogen Abuse with Unspecified Hallucinogen-Induced Disorder

description: Evidence of hallucinogen abuse with unspecified hallucinogen-induced disorder.


name: Jejunum and Ileum Neuroendocrine Tumor cM1c TNM Finding v8

description: Jejunum and ileum neuroendocrine tumor with both hepatic and extrahepatic metastases. (from AJCC 8th Ed.)


Metastatic Fallopian Tube Carcinoma

description: A carcinoma that arises from the fallopian tube and has metastasized to another anatomic site.


Appendix Perforation, CTCAE

description: Appendix Perforation that is temporally associated with the use of a medical treatment or procedure, and that may or may not be considered related to the medical treatment or procedure.


Predominantly Fatty Breast

description: The breasts are almost entirely fatty, as defined by the visually estimated content of fibroglandular-density tissue within the breast, based on updated editions of the American College of Radiology's Breast Imaging Reporting and Data System (BI-RADS).


Grade 5 Disease Progression, CTCAE

description: Death


PSA Level 0.2 to Two

description: A blood concentration of prostate specific antigen between 0.2 and 2 ng/mL.


name: Peripheral Motor Nerve NOS Intra-Operative Injury, CTCAE


name: Atherosclerosis of Non-Autologous Biological Bypass Graft(s) of the Extremities with Gangrene, Left Leg

description: Evidence of atherosclerosis of non-autologous biological bypass graft(s) of the extremities with gangrene in the left leg.


Proliferative Actinic Keratosis

description: Actinic keratosis characterized by the presence of dermal projections of nested atypical keratinocytes and dense dermal inflammation.


name: Other Specified Diabetes Mellitus with Moderate Nonproliferative Diabetic Retinopathy with Macular Edema

description: Evidence of other specified diabetes mellitus with moderate nonproliferative diabetic retinopathy with macular edema not specified elsewhere.


Felty's Syndrome, Right Wrist

description: Evidence of Felty's syndrome in the right wrist.


name: Monoclonal Gammopathy of Renal Significance

description: A condition caused by a B-cell or plasma cell clone resulting in the deposition of the secreted monoclonal immunoglobulin, without evidence for overt lymphoma or myeloma. This category includes a wide spectrum of renal pathology and include such lesions as immunoglobulin-associated amyloidosis, the monoclonal immunoglobulin deposition diseases (MIDDs; light chain deposition disease, heavy chain deposition disease, and light and heavy chain deposition disease), proliferative glomerulonephritis with monoclonal immunoglobulin deposits (PGNMID), C3 glomerulopathy with monoclonal gammopathy, light chain proximal tubulopathy (Fanconi syndrome), and several others.


Grade 1 Anosmia, CTCAE

description: Present


name: Unresectable Malignant Digestive System Neoplasm

description: A malignant digestive system neoplasm that is not amenable to surgical resection.


description: The state when recipients of hematopoietic stem cell transplantations are not fully matched with their unrelated adult volunteer donors for HLA-A, HLA-B, HLA-C, and HLA-DRB1 and the homozygous recipient is receiving a graft from a heterozygous donor.


No Radiating Chest Pain

description: An indication that the chest pain dose not radiate.


name: Cranial Nerve VI Intra-Operative Injury, CTCAE


name: Diabetes Mellitus due to Underlying Condition with Hypoglycemia without Coma

description: Evidence of diabetes mellitus due to underlying condition with hypoglycemia without coma.


Grade 2 Mitral Valve Disease, CTCAE

description: Asymptomatic; moderate regurgitation or stenosis by imaging


Lung Cancer pN3 TNM Finding v8

description: Lung cancer with metastasis in contralateral mediastinal, contralateral hilar, ipsilateral or contralateral scalene, or supraclavicular lymph node(s). (from AJCC 8th Ed.)


Grade 5 Salivary Gland Fistula, CTCAE

description: Death


Grade 5 Infective Myositis, CTCAE

description: Death


name: Breakdown of Biological Heart Valve Graft, Sequela

description: Evidence of the sequela of the breakdown of a biological heart valve graft.


name: Mycosis fungoides of intrathoracic lymph nodes

description: Evidence of mycosis fungoides, intrathoracic lymph nodes.


name: Grade 2 Lower Extremity Soft Tissue Necrosis, CTCAE


name: Grade 2 Intraoperative Gastrointestinal Injury, CTCAE

description: Partial resection of injured organ/structure indicated


name: Outer Ear Pinna Intra-Operative Injury, CTCAE


name: Atherosclerosis of Non-Biological Bypass Graft(s) of the Extremities with Intermittent Claudication, Left Leg

description: Evidence of atherosclerosis of non-biological bypass graft(s) of the extremities with intermittent claudication in the left leg.


name: Grade 1 Cranial Nerve X Intra-Operative Injury, CTCAE


name: Melanoma in Chronically Sun-Exposed Skin

description: A melanoma that arises from a chronically sun-exposed skin area. It is associated with severe actinic keratosis.


name: Cerebral Infarction due to Thrombosis of Right Middle Cerebral Artery

description: Evidence of cerebral infarction due to a thrombosis of the right middle cerebral artery.


name: Exocrine Pancreatic Cancer Pathologic TNM Finding v8

description: A pathologic finding about one or more characteristics of exocrine pancreatic cancer, following the rules of the TNM AJCC v8 classification system.


name: Melanoma in situ of upper limb, including shoulder

description: Evidence of melanoma in situ of upper limb including the shoulder.


name: Cardiac Failure due to Anesthesia During Pregnancy, First Trimester

description: Evidence of cardiac failure due to anesthesia during pregnancy in the first trimester.


name: Ungual Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


name: Rheumatoid Lung Disease with Rheumatoid Arthritis of Right Hand

description: Evidence of rheumatoid lung disease with rheumatoid arthritis of right hand.


Grade 4 Pancreatic Duct Stenosis, CTCAE

description: Life-threatening consequences; urgent operative intervention indicated


name: Other Specified Diabetes Mellitus with Mild Nonproliferative Diabetic Retinopathy without Macular Edema

description: Evidence of other specified diabetes mellitus with mild nonproliferative diabetic retinopathy without macular edema not specified elsewhere.


Exaggerated placental site

description: A non-neoplastic trophoblastic disorder characterized by the presence of an increased number of implantation-site intermediate trophoblasts infiltrating the endometrium and myometrium extensively. It is associated with pregnancy or abortion.


name: Grade 5 Spinal Cord Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


Grade 3 Anxiety, CTCAE

description: Severe symptoms; limiting self care ADL; hospitalization indicated


PSA Level Greater than or Equal to 0.2

description: A blood concentration of prostate specific antigen greater than or equal to 0.2 ng/mL.


Cutaneous Melanoma pN2 TNM Finding v8

description: Cutaneous melanoma with two or three tumor-involved nodes or in-transit satellite, and/or microsatellite metastases with one tumor-involved node. (from AJCC 8th Ed.)


Stage III Esophageal Cancer

description: Stage III includes: T3, N1, M0 and T4, Any N, M0) T3: Tumor invades adventitia. T4: Tumor invades adjacent structures. N0: No regional lymph node metastasis. N1: Regional lymph node metastasis. M0: No distant metastasis. (AJCC 6th ed.) -2003


name: Unspecified Pre-Existing Diabetes Mellitus in Pregnancy, Second Trimester

description: Evidence of unspecified pre-existing diabetes mellitus in pregnancy in the second trimester.


name: Stage IV Digestive System Neuroendocrine Tumor AJCC v7

description: Stage IV includes: Any T, Any N, M1. M1: Distant metastasis.  (AJCC 7th ed.)


name: Major Salivary Gland Cancer Clinical Distant Metastasis TNM Finding v8

description: A clinical finding about one or more characteristics of major salivary gland cancer, following the rules of the TNM AJCC v8 classification system as they pertain to distant metastases.


Scrotal Cyst

description: A cystic lesion located in the scrotum.


name: International Normalized Ratio of Prothrombin Time Level Finding

description: A finding that indicates the international normalized ratio of prothrombin time level in a sample.


name: Stage I Digestive System Neuroendocrine Tumor AJCC v7

description: Stage I includes: T1, N0, M0.  T1: Stomach: tumor invades lamina propria or submucosa and is 1 cm or less in size; duodenum /jejunum/ileum: tumor invades lamina propria or submucosa and is 1 cm or less in size; ampulla: tumor 1 cm or less; colon or rectum: tumor invades lamina propria or submucosa and is 2 cm or less.  N0: No regional lymph node metastasis.  M0: No distant metastasis. (AJCC 7th ed.)


name: Grade 5 Scrotum Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


name: Grade 2 Spleen Intra-Operative Injury, CTCAE


Colonic Hemorrhage, CTCAE

description: A disorder characterized by bleeding from the colon.


Grade 5 Esophageal Perforation, CTCAE

description: Death


Neonatal encephalopathy

description: Abnormal functioning of the central nervous system in the newborn period that may be due to a variety of etiologies including hypoxia/ischemia, metabolic disturbance, or infection.


Cervical Cancer cT2a TNM Finding v8

description: Cervical carcinoma invading beyond the uterus but not to the pelvic wall or to lower third of vagina without parametrial invasion. (from AJCC 8th Ed.)


Grade 1 Rash Acneiform, CTCAE

description: Papules and/or pustules covering <10% BSA, which may or may not be associated with symptoms of pruritus or tenderness


name: Grade 4 Forced Expiratory Volume Decreased, CTCAE


Pre-Pre-B Acute Lymphoblastic Leukemia

description: Acute lymphoblastic leukemia of early B-lineage.


Electrical Fire Smoke Exposure

description: Environmental or occupational exposure to airborne gases and particulates produced during an electrical fire.


name: Grade 5 Pharynx Mucositis or Stomatitis by Clinical Examination Classification, CTCAE


name: Advanced Pancreatic Neuroendocrine Neoplasm

description: A pancreatic neuroendocrine neoplasm that has spread extensively to other anatomic sites or is no longer responding to treatment.


Common blue nevus of skin

description: A blue nevus that is not associated with increased cellularity.


name: Grade 2 Fallopian Tube Stricture or Stenosis, CTCAE


name: Grade 2 Injury To Inferior Vena Cava, CTCAE

description: Symptomatic; repair or revision not indicated


Neuromuscular hamartoma

description: A very rare intraneural mass in a large nerve characterized by the interposition of mature skeletal muscle fibers and nerve fibers.


Metastatic Bladder Urothelial Carcinoma

description: Bladder urothelial carcinoma that has spread to another anatomical site.


Kidney Cancer Clinical TNM Finding v6

description: A clinical finding about one or more characteristics of kidney cancer, following the rules of the TNM AJCC v6 classification system.


name: Other Generalized Epilepsy, Intractable, with Status Epilepticus

description: Evidence of other generalized epilepsy, with status epilepticus that does not respond optimally to treatment not specified elsewhere.


Grade 4 Myocardial Infarction, CTCAE

description: Life-threatening consequences; hemodynamically unstable


name: Metastatic Malignant Peripheral Nerve Sheath Tumor

description: The presence of malignant Schwann cell growth (benign variant is known as neurofibroma) at a site removed from the primary site of tumor growth.


undifferentiated carcinoma of cervix

description: A rare carcinoma that arises from the cervix and is characterized by the lack of specific cellular differentiation.


name: Simple dislocation, multiple and ill-defined sites

description: Multiple bone displacements without clear distinction that are not associated with an external wound.


name: Distal Bile Duct Cancer Pathologic Primary Tumor TNM Finding v7

description: A pathologic finding about one or more characteristics of distal bile duct cancer, following the rules of the TNM AJCC v7 classification system as they pertain to staging of the primary tumor.


name: Maxillary Sinus Cancer pT4a TNM Finding v6

description: Maxillary sinus cancer with tumor invading anterior orbital contents, skin of cheek, pterygoid plates, infratemporal fossa, cribriform plate, sphenoid or frontal sinuses. (from AJCC 6th Ed.)


Ovarian Hemorrhage, CTCAE

description: A disorder characterized by bleeding from the ovary.


name: Refractory Non-Muscle Invasive Bladder Urothelial Carcinoma

description: Non-muscle invasive bladder urothelial carcinoma that is resistant to treatment.


name: Uterine Corpus Adenosarcoma pT3a TNM Finding v8

description: Uterine corpus adenosarcoma with tumor infiltrating abdominal tissues at one site. (from AJCC 8th Ed.)


Grade 2 Bruising, CTCAE

description: Generalized


name: Adult Mixed Cellularity Classical Hodgkin Lymphoma

description: Mixed cellularity classic Hodgkin lymphoma occurring in adults.


Liver Cancer Pathologic TNM Finding v7

description: A pathologic finding about one or more characteristics of liver cancer, following the rules of the TNM AJCC v7 classification system.  Complete pathologic staging consists of evaluation of the primary tumor, including histologic grade, regional lymph node status, and underlying liver disease.  Regional lymph node involvement is rare (5%) except in the fibrolamellar variant of hepatocellular carcinoma. (from AJCC 7th Ed.)


name: Maxillary Sinus Cancer Pathologic Regional Lymph Nodes TNM Finding v6

description: A pathologic finding about one or more characteristics of maxillary sinus cancer, following the rules of the TNM AJCC v6 classification system as they pertain to staging of regional lymph nodes.


Narcolepsy-Cataplexy Syndrome

description: Evidence of narcolepsy with cataplexy.


Prostate Neuroendocrine Tumor

description: An extremely rare, slow-growing well-differentiated neuroendocrine neoplasm that affects the prostate gland.


Iris Melanoma pT4b TNM Finding v8

description: Iris melanoma with extrascleral extension more than 5 mm in largest diameter. (from AJCC 8th Ed.)


name: Acute Myelomonocytic Leukemia without Abnormal Eosinophils

description: Acute myelomonocytic leukemia without an abnormal eosinophilic component in the bone marrow.


Acquired Factor XII Deficiency

description: An acquired coagulation disorder characterized by the partial or complete absence of factor XII activity in the blood.


name: Diffuse Laminar Endocervical Hyperplasia

description: A benign band-like proliferation of tightly-packed, small to medium sized endocervical glands below the surface of the endocervical canal.


name: Grade 4 Colon Intra-Operative Injury, CTCAE


Grade 3 Tracheal Obstruction, CTCAE

description: Stridor or respiratory distress limiting self care ADL; invasive intervention indicated (e.g., stent, laser)


name: Other Non-Rheumatic Pulmonary Valve Disorders

description: Evidence of other non-rheumatic pulmonary valve disorders not specified elsewhere.


Breast Cancer cM0 TNM Finding v8

description: Breast cancer without clinical or radiographic evidence of distant metastases. Imaging studies are not required to assign the cM0 category. (from AJCC 8th Ed.)


name: Grade 1 Cranial Nerve V Neuropathy, CTCAE


Mesenteric abscess

description: An abscess that is located in any part of the tissue composing the mesentery, and that generally arises from an infection in an adjacent area of the intestine.


name: Acute Myeloid Leukemia with U2AF1 Mutation

description: An acute myeloid leukemia associated with U2AF1 gene mutation.


HCV Genotype Finding

description: The determination of the genotype of hepatitis c virus in a blood sample.


name: Other Specified Diabetes Mellitus with Diabetic Peripheral Angiopathy with Gangrene

description: Evidence of other specified diabetes mellitus with diabetic peripheral angiopathy with gangrene not specified elsewhere.


Subungual Melanoma

description: A melanoma that arises from the area underneath a fingernail or toenail. It affects the fingernails more often than the toenails.


Pathologic Response

description: An evaluation of the pathologic response of the disease to the therapy.


Normal Urine Test Result

description: A laboratory test result indicating that the analysis of a urine sample revealed normal values.


name: Uveal Melanoma Clinical Distant Metastasis TNM Finding v8

description: A clinical finding about one or more characteristics of uveal melanoma, following the rules of the TNM AJCC v8 classification system as they pertain to distant metastases.


name: Rheumatoid Heart Disease with Rheumatoid Arthritis of Right Hip

description: Evidence of rheumatoid heart disease with rheumatoid arthritis of right hip.


Accident involving aircraft, NOS

description: An accident taking place aboard, or involving, any type of aircraft.


name: Grade 2 Infections and Infestations - Other, Specify, CTCAE

description: Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL


name: Lip and Oral Cavity Cancer Pathologic TNM Finding v6

description: A pathologic finding about one or more characteristics of lip and oral cavity cancer, following the rules of the TNM AJCC v6 classification system.


Erythema Multiforme, CTCAE

description: A disorder characterized by target lesions (a pink-red ring around a pale center).


name: Lip and Oral Cavity Cancer pT2 TNM Finding v8

description: Lip and oral cavity cancer with tumor size 2 cm or less in greatest dimension, DOI greater than 5 mm and equal or less than 10 mm or tumor greater than 2 cm but 4 cm or less in greatest dimension and 10 mm or less DOI. (from AJCC 8th Ed.)


name: Distal Bile Duct Cancer cM1 TNM Finding v8

description: Distal bile duct cancer with distant metastasis. (from AJCC 8th Ed.)


Refractory Erdheim-Chester Disease

description: Erdheim-Chester disease that does not respond to treatment.


Needle Tract Seeding

description: The implantation of tumor cells to surrounding tissue along the course of a contaminated instrument such as a biopsy needle or laparoscope.


Stage IV Cervical Cancer AJCC v8

description: Stage IV includes: IVA: T4, Any N, M0; IVB: Any T, Any N, M1. T4: Tumor invading the mucosa of the bladder or rectum, and/or extending beyond the true pelvis (bullous edema is not sufficient to classify a tumor as T4). M0: No distant metastasis. M1: Distant metastasis (including peritoneal spread or involvement of the supraclavicular, mediastinal, or distant lymph nodes; lung; liver; or bone). (from AJCC 8th Ed.)


name: Other specified systemic involvement of connective tissue

description: Evidence of other specified systemic involvement of connective tissue not specified elsewhere.


Grade 3 Alkalosis, CTCAE

description: pH >7.5


pM1a TNM Finding

description: A pathologic primary tumor TNM finding. The definition of PM1a finding depends on the particular type of cancer that it refers to; for example, for bladder cancer, PM1a finding is defined as follows: cancer with distant metastasis limited to lymph nodes beyond the common iliacs. (from AJCC 8th Ed.)


Stage IIIB Vulvar Cancer AJCC v8

description: Stage IIIB includes: T1-T2, N2a, N2b, M0. T1: Tumor confined to the vulva and/or perineum. Multifocal lesions should be designated as such. The largest lesion or the lesion with the greatest depth of invasion will be the target lesion identified to address the highest pT stage. Depth of invasion is defined as the measurement of the tumor from the epithelial-stromal junction of the adjacent most superficial dermal papilla to the deepest point of invasion. T2: Tumor of any size with extension to adjacent perineal structures (lower/distal third of the urethra, lower/distal third of the vagina, anal involvement). N2a: Three or more lymph node metastases each less than 5 mm. It includes micrometastasis, N2mi. N2b: Two or more lymph node metastases equal to 5 mm. M0: No distant metastasis. (AJCC 8th Ed.)


name: Lens Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


TET2 Negative

description: An indication that TET2 expression or activity has not been detected in a sample.


Grade 2 Neonatal Diarrhea, AE

description: An adverse event in a newborn characterized by an increase of 4 - 6 stools per day over baseline; moderate increase in ostomy output compared to baseline.


Grade 3 Edema Face, CTCAE

description: Severe swelling; limiting self care ADL


Grade 1 Stomal Ulcer, CTCAE

description: Asymptomatic; clinical or diagnostic observations only; intervention not indicated


Benzene-Related Acute Myeloid Leukemia

description: Acute myeloid leukemia caused by benzene.


name: Atherosclerosis of Autologous Vein Bypass Graft(s) of Other Extremity with Rest Pain, Unspecified Extremity

description: Evidence of atherosclerosis of autologous vein bypass graft(s) of other extremity with rest pain, unspecified extremity.


Decreased CYBA Expression

description: An indication that the expression of CYBA is lower than the normal range of values.


Stage IV Gastric Cancer with Metastasis

description: T4,N2,MO (from PDQ)


psoriatic juvenile arthropathy

description: Evidence of psoriatic juvenile arthropathy.


name: Gastric Neuroendocrine Tumor Pathologic Regional Lymph Nodes TNM Finding v8

description: A pathologic finding about one or more characteristics of a gastric neuroendocrine tumor, following the rules of the TNM AJCC v8 classification system as they pertain to staging of regional lymph nodes.


Carcinoma in situ of scrotum

description: Evidence of carcinoma in situ of the scrotum.


name: DYSKERATOSIS CONGENITA, AUTOSOMAL RECESSIVE 6

description: Dyskeratosis congenita caused by autosomal recessive mutation(s) in the PARN gene, encoding poly(A)-specific ribonuclease PARN.


Grade 1 Nail Changes, CTCAE

description: Present


Tumor Less than or Equal to 2.0 cm

description: A tumor where the greatest dimension is less than or equal to 2.0 cm.


Grade 3 Conjunctivitis Infective, CTCAE

description: IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated


Thymic Tumor pN1 TNM Finding v8

description: Thymic tumor with metastasis in anterior (perithymic) lymph nodes. (from AJCC 8th Ed.)


name: Bladder Cancer Pathologic Regional Lymph Nodes TNM Finding v8

description: A pathologic finding about one or more characteristics of bladder cancer, following the rules of the TNM AJCC v8 classification system as they pertain to staging of regional lymph nodes.


name: Grade 2 Face NOS Intra-Operative Injury, CTCAE


name: Acute on chronic diastolic heart failure

description: Acute decompensation of chronic diastolic congestive heart failure.


EBV Molecular Test Result

description: The outcome of Epstein-Barr virus molecular testing.


Cervical Cancer cT0 TNM Finding v8

description: Cervical cancer with no evidence of primary tumor. (from AJCC 8th Ed.)


name: Diseases of the Nervous System Complicating Pregnancy, Unspecified Trimester

description: Evidence of diseases of the nervous system complicating pregnancy in an unspecified trimester.


Benign Paratesticular Neoplasm

description: A neoplasm that arises from the paratesticular structures and is characterized by the absence of atypical or malignant cytological and architectural features, and absence of invasive features or metastatic potential.


name: Jejunum Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


Neonatal respiratory system disorder

description: A respiratory system disorder that occurs during the neonatal period. A representative example is the respiratory distress syndrome.


Penile Infection

description: An infectious process affecting the penis.


anemia complicating childbirth

description: Evidence of anemia complicating childbirth.


Grade 2 Myasthenia Gravis, CTCAE

description: Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL


Grade 2 Scrotal Infection, CTCAE

description: Oral intervention indicated (e.g., antibiotic, antifungal, or antiviral)


Oral Multifocal Epithelial Hyperplasia

description: Benign multifocal squamous epithelial proliferation affecting the oral mucosa. It is associated with human papilloma virus infection.


name: Chemotherapy-induced nausea and vomiting

description: Nausea and/or vomiting co-occurring with a cycle of chemotherapy.


Syringomyelia and Hydromyelia

description: Syringomyelia associated with accumulation of cerebrospinal fluid in the spinal cord.


Retinoblastoma pT3d TNM Finding v8

description: Full-thickness invasion into the outer third of the sclera and/or invasion into or around emissary channels. (from AJCC 8th Ed.)


name: Ampulla of Vater Cancer pT2 TNM Finding v8

description: Ampulla of Vater cancer with tumor invading into the muscularis propria of the duodenum. (from AJCC 8th Ed.)


name: Intrahepatic Bile Duct Cancer pTX TNM Finding v8

description: Intrahepatic bile duct cancer in which the primary tumor cannot be assessed. (from AJCC 8th Ed.)


Cutaneous Melanoma cN3 TNM Finding v8

description: Cutaneous melanoma with four or more tumor-involved nodes or in-transit satellite, and/or microsatellite metastases with two or more tumor-involved nodes, or any number of matted nodes without or with in-transit, satellite, and/or microsatellite metastases. (from AJCC 8th Ed.)


name: Grade 2 Superior Vena Cava Intra-Operative Injury, CTCAE


name: Diabetes Mellitus due to Underlying Condition with Proliferative Diabetic Retinopathy with Traction Retinal Detachment not Involving the Macula, Right Eye

description: Evidence of diabetes mellitus due to underlying condition with proliferative diabetic retinopathy with traction retinal detachment not involving the macula in the right eye.


name: Grade 3 Trachea Mucositis or Stomatitis by Clinical Examination Classification, CTCAE


Grade 4 Burn, CTCAE

description: Life-threatening consequences


Complication of transplanted pancreas

description: A disease or disorder that is associated with a transplanted pancreas.


name: Non-Infectious Wound Complication, CTCAE


name: Carcinoma of the Eyelid pT2b TNM Finding v7

description: Carcinoma of the eyelid with tumor measuring more than 10 mm, but not more than 20 mm in greatest dimension.  Or, tumor involving the full thickness of eyelid.  (from AJCC 7th Ed.)


Grade 4 Laryngeal Stenosis, CTCAE

description: Life-threatening consequences; urgent intervention indicated


Palsy of vagus nerve

description: Partial or complete paralysis of the vagus nerve.


name: Obesity Complicating Pregnancy, Unspecified Trimester

description: Evidence of obesity complicating pregnancy in an unspecified trimester.


Prostate Cancer cM1c TNM Finding v8

description: Prostate cancer with metastasis to other site(s) with or without bone disease. (from AJCC 8th Ed.)


name: Monoplegia of Upper Limb following Cerebral Infarction Affecting Left Non-Dominant Side

description: Evidence of monoplegia of upper limb following cerebral infarction affecting left non-dominant side.


name: Hypothyroidism due to medicaments and other exogenous substances

description: Evidence of hypothyroidism due to medicaments and other exogenous substances.


name: Grade 3 Esophagus Mucositis or Stomatitis by Functional or Symptomatic Classification, CTCAE


name: Malignant Neoplasm of Nipple and Areola, Right Male Breast

description: Evidence of a malignant neoplasm of the nipple and areola in the right male breast.


Facial Nerve Palsy Related to Birth

description: A condition characterized by reduced or absent movement of the ipsilateral face as a consequence of an injury to the seventh cranial nerve sustained during the birthing process.


Grade 5 Pericarditis, CTCAE

description: Death


Grade 3 Myasthenia Gravis, CTCAE

description: Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL


Renal Colic, CTCAE

description: A disorder characterized by paroxysmal and severe flank marked discomfort radiating to the inguinal area. Often, the cause is the passage of crystals/kidney stones.


name: Grade 2 Pleura Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


name: Patient Chemical Contamination Due To Medical Device Failure Or Malfunction


name: FIGO Stage IIIC Gestational Trophoblastic Tumor


Adenosarcoma TNM Finding v7

description: A finding about one or more characteristics of adenosarcoma, following the rules of the TNM AJCC v7 classification system.


Grade 1 Optic Nerve Disorder, CTCAE

description: Asymptomatic; clinical or diagnostic observations only


name: Squamous cell carcinoma, clear cell type

description: A squamous cell carcinoma characterized by the presence of malignant cells with clear cytoplasm.


name: Transitional cell cancer of renal pelvis and ureter metastatic

description: A urothelial carcinoma of the renal pelvis and ureter that has spread from its original site of growth to another anatomic site.


name: Grade 1 Intraoperative Urinary Injury, CTCAE

description: Primary repair of injured organ/structure indicated


Broad Ligament Ependymoma

description: A rare neoplasm that arises from the broad ligament and shows ependymal differentiation.


KIT K642E Negative

description: A finding indicating that expression of the mast/stem cell growth factor receptor Kit protein with the amino acid substitution Lys642Glu (K642E) has not been detected in a sample.


name: RASGRP1/APTX Ratio Equal or Greater than 5

description: An assay finding indicating that the ratio of the gene pair RASGRP1/APTX that is expressed in leukemic cells is equal to or greater than five.


Mouth Complete Response GvHD

description: An NIH modified Oral Mucosa Rating Scale (OMRS) score of 0 following previous GvHD involvement.


name: Atherosclerosis of Non-Biological Bypass Graft(s) of the Extremities with Rest Pain, Right Leg

description: Evidence of atherosclerosis of non-biological bypass graft(s) of the extremities with rest pain in the right leg.


Appendix Serrated Lesions and Polyps

description: Polyps that arises from the appendix. They are characterized by the presence of serrated glands and the absence of generalized dysplasia.


name: Atherosclerosis of Autologous Vein Bypass Graft(s) of the Left Leg with Ulceration of Thigh

description: Evidence of atherosclerosis of autologous vein bypass graft(s) of the left leg with ulceration of thigh.


name: Appendix Neuroendocrine Tumor cM0 TNM Finding v8

description: Appendix neuroendocrine tumor without evidence of distant metastasis. (from AJCC 8th Ed.)


name: Grade 5 Upper Gastrointestinal Hemorrhage NOS, CTCAE


name: Ovarian, Fallopian Tube, and Primary Peritoneal Carcinoma Clinical TNM Finding v8

description: A clinical finding about one or more characteristics of ovarian, fallopian tube, or primary peritoneal carcinoma, following the rules of the TNM AJCC v8 classification system.


Cutaneous Melanoma pT4a TNM Finding v8

description: Cutaneous melanoma measuring more than 4.0 mm in thickness. Ulceration status: Without ulceration. (from AJCC 8th Ed.)


Cutaneous Melanoma pM1b TNM Finding v7

description: Cutaneous melanoma with metastases to lung associated with normal serum lactate dehydrogenase (LDH). (from AJCC 7th Ed.)


Recurrent Neuroendocrine Carcinoma

description: The reemergence of neuroendocrine carcinoma after a period of remission.


COVID-19-Associated Ataxia

description: Ataxia caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).


Positive EBV Test

description: A laboratory test result indicating the presence of the Epstein-Barr virus in a biological sample.


name: Grade 2 Cranial Nerve I Neuropathy, CTCAE


Spitz Tumor

description: A term that refers to a group of melanocytic neoplasms that are composed of epithelioid and/or spindle cells and extend from the epidermis into the reticular dermis, often in a wedge-shaped configuration. They are usually associated with oncogenic mutations that activate the MAP-kinase pathway. This category includes Spitz nevus, Spitz melanocytoma, and Spitz melanoma.


Global Relapse in Lymph Nodes

description: Any new lymph node greater than 1.5 cm in the long axis in those with complete response proven to be N3 histologically.


Childhood Granular Cell Tumor

description: A granular cell tumor that occurs during childhood.


Intercellular Signaling Alteration

description: Intercellular Signaling Alteration involves a change in the quality of the existing state of communication between cells, whether by direct cell contact or by chemical signals.


name: Rheumatoid Arthritis without Rheumatoid Factor, Right Knee

description: Evidence of rheumatoid arthritis without rheumatoid factor in the right knee.


Thrush, CTCAE

description: A disorder characterized by a suspected candidal infection involving an oral mucosal surface.


Atypical meningioma

description: A WHO grade II meningioma characterized by the presence of brain invasion and an increased mitotic activity, or at least three of the following morphologic features: small cells, high cellularity, prominent nucleoli, lack of architectural pattern, and necrosis.


Grade 1 Hyperlipidemia, CTCAE

description: Requiring diet changes


Stage IVA Osteosarcoma AJCC v7

description: Stage IVA includes: Any T, N0, M1a, Any G.  N0: No regional lymph node metastasis.  M1a: Distant metastasis to lung. (AJCC 7th ed.)


Breast Cancer cN3 TNM Finding v6

description: Breast cancer with metastasis in ipsilateral infraclavicular lymph node(s) with or without axillary lymph node involvement, or in clinically apparent ipsilateral internal mammary lymph node(s) and in the presence of clinically evident axillary lymph node metastasis; or metastasis in ipsilateral supraclavicular lymph node(s) with or without axillary or internal mammary lymph node involvement. (from AJCC 6th Ed.)


name: Duodenum and Ampulla of Vater Neuroendocrine Tumor TNM Finding v8

description: A finding about one or more characteristics of a duodenum and ampulla of Vater neuroendocrine tumor, following the rules of the TNM AJCC v8 classification system. This classification system applies to well-differentiated neuroendocrine tumors of the duodenum and ampulla of Vater. Carcinomas of the duodenum, including high-grade (grade 3), poorly differentiated neuroendocrine carcinomas and carcinomas of the ampulla of Vater, including high-grade (grade 3), poorly differentiated neuroendocrine carcinomas are not included in this classification system. (from AJCC 8th Ed.)


name: Atherosclerosis of Non-Biological Bypass Graft(s) of the Extremities with Rest Pain, Bilateral Legs

description: Evidence of atherosclerosis of non-biological bypass graft(s) of the extremities with rest pain in both legs.


name: Grade 4 Bronchus Intra-Operative Injury, CTCAE


PSA Failure

description: An increase in serum prostate-specific antigen (PSA) levels following treatment for prostate cancer.


name: Cerebral Infarction due to Unspecified Occlusion or Stenosis of Unspecified Precerebral Artery

description: Evidence of cerebral infarction due to an unspecified occlusion or stenosis of an unspecified precerebral artery.


Ophthalmic Sites Cancer TNM Finding v8

description: A finding about one or more characteristics of ophthalmic sites cancer, following the rules of the TNM AJCC v8 classification system.


name: Other Stimulant Dependence with Withdrawal

description: Evidence of other stimulant dependence with withdrawal not specified elsewhere.


Grade 2 Watering Eyes, CTCAE

description: Symptomatic; moderate decrease in visual acuity (best corrected visual acuity 20/40 and better or 3 lines or less decreased vision from known baseline)


Homicidal Ideation

description: Thinking about ending or making plans to end another's life.


name: Ovarian Cancer and Primary Peritoneal Carcinoma Clinical Distant Metastasis TNM Finding v7

description: A clinical finding about one or more characteristics of ovarian cancer or primary peritoneal carcinoma, following the rules of the TNM AJCC v7 classification system as they pertain to distant metastases.


name: Lip and Oral Cavity Cancer Clinical Distant Metastasis TNM Finding v8

description: A clinical finding about one or more characteristics of lip and oral cavity cancer, following the rules of the TNM AJCC v8 classification system as they pertain to distant metastases.


Secondary Cause of Death

description: The second significant event which ultimately led to death.


name: Blood Lactate Dehydrogenase Increased, CTCAE

description: A finding based on laboratory test results that indicate increased levels of lactate dehydrogenase in the blood specimen.


Resectable Astrocytoma

description: An astrocytoma that is amenable to surgical resection.


Grade 3 Pericardial Effusion, CTCAE

description: Effusion with physiologic consequences


name: Acute Myeloid Leukemia Arising from Previous Myeloproliferative Neoplasm

description: An acute myeloid leukemia developing in patients with a prior history of myeloproliferative neoplasm.


name: Grade 1 Neonatal Respiratory Distress Syndrome, AE

description: An adverse event in a newborn characterized by radiological evidence without clinical signs; clinical evidence of mildly increased respiratory distress (e.g. increased work of breathing) without significant deterioration in gas exchange (increase in partial pressure of carbon dioxide (pCO2) or decrease in oxygenation); no supportive care required.


name: Perihilar Bile Duct Cancer cM0 TNM Finding v8

description: Perihilar bile duct cancer without evidence of distant metastasis. (from AJCC 8th Ed.)


Grade 3 Sinus Disorder, CTCAE

description: Stenosis with significant nasal obstruction; limiting self care ADL


Grade 1 Adrenal Insufficiency, CTCAE

description: Asymptomatic; clinical or diagnostic observations only; intervention not indicated


Grade 4 Oral Cavity Fistula, CTCAE

description: Life-threatening consequences; urgent intervention indicated


Cardiac tuberculosis

description: Tuberculosis affecting the heart.


name: Atherosclerosis of Native Arteries of Extremities with Intermittent Claudication, Right Leg

description: Evidence of atherosclerosis of native arteries of extremities with intermittent claudication in the right leg.


Skin tear

description: A break in skin tissue caused by friction or shearing.


Grade 2 Vaginal Anastomotic Leak, CTCAE

description: Symptomatic; medical intervention indicated


name: Grade 2 Abdomen Infection NOS Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


name: Grade 2 Neoplasms Benign, Malignant and Unspecified (Incl Cysts and Polyps) - Other, Specify, CTCAE

description: Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL


Sinus perforation

description: A rupture in the sinus tissue due to traumatic or pathologic processes.


Post-Mastectomy Pain Syndrome

description: Chronic pain following mastectomy or lumpectomy that usually affects the anterior thorax, axilla, and/or medial upper arm.


Grade 4 Laryngospasm, CTCAE

description: Persistent or severe episodes associated with syncope; urgent intervention indicated (e.g., fiberoptic laryngoscopy, intubation, botox injection)


Radiation Damage

description: Injury resulting from exposure to ionizing radiation.


name: Atherosclerosis of Unspecified Type of Bypass Graft(s) of the Right Leg with Ulceration of Calf

description: Evidence of atherosclerosis of unspecified type of bypass graft(s) of the right leg with ulceration of calf.


name: Grade 4 Salivary Gland or Saliva Changes, CTCAE


name: Myxoid Glioneuronal Tumor of the Septum Pellucidum

description: A myxoid glioneuronal tumor that arises from the septum pellucidum.


name: Grade 1 Rectum Stricture or Stenosis, CTCAE


Refractory Bladder Urothelial Carcinoma

description: Bladder urothelial carcinoma that does not respond to treatment.


Increased Emotional State

description: A state of mental excitement, characterized by physiological and behavioral changes.


name: Cerebral Infarction due to Thrombosis of Left Carotid Artery

description: Evidence of cerebral infarction due to a thrombosis of the left carotid artery.


Lung Cancer pT1 TNM Finding v7

description: Lung cancer with a tumor size of 3 cm or less in greatest dimension, surrounded by lung or visceral pleura and without bronchoscopic evidence of invasion more proximal than the lobar bronchus (i.e., not in the main bronchus). The uncommon superficial tumor of any size with its invasive component limited to the bronchial wall, which may extend proximal to the main bronchus, is also classified as T1a. (from AJCC 7th Ed.)


name: Grade 4 Pulmonary Fibrosis Radiographic Changes, CTCAE


name: Grade 4 Pancreas Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


name: Grade 1 Biliary Tree Left Hepatic Duct Intra-Operative Injury, CTCAE


name: Grade 1 Other Pulmonary and Upper Respiratory, CTCAE


name: Gastrointestinal Stromal Tumor of Other Site

description: Evidence of gastrointestinal stromal tumor of other site.


T2a TNM Finding

description: A general term that refers to a TNM finding of a primary tumor growth beyond the level of in situ cancer, minimal subepithelial invasion, or minimal greatest diameter. The definition of T2a TNM finding depends on the specific type of cancer that it refers to; for example, for kidney cancer it refers to a primary tumor that measures more than 7 cm but less than or equal to 10 cm in greatest dimension, and is limited to the kidney; for bladder cancer it refers to a primary tumor that invades the superficial muscularis propria (inner half); for cervical cancer it refers to a primary tumor that invades beyond the uterus but not to the pelvic wall or to the lower third of vagina and there is no parametrial invasion.


name: Grade 2 Conjunctiva Infection with Unknown Absolute Neutrophil Count, CTCAE


Childhood Fibrous Dysplasia

description: Fibrous dysplasia that occurs during childhood.


Hypertrophic Actinic Keratosis

description: Actinic keratosis characterized by the presence of epidermal hyperplasia, parakeratosis, and orthokeratosis.


name: Uterus Infection with Unknown Absolute Neutrophil Count, CTCAE


name: Head and Neck Cancer pN2b TNM Finding v8

description: Head and neck cancer with metastases in multiple ipsilateral lymph nodes, none larger than 6 cm in greatest dimension and ENE(-); (from AJCC 8th Ed.)


Grade 5 Bronchospasm, CTCAE

description: Death


name: Refractory Anaplastic Pleomorphic Xanthoastrocytoma

description: Anaplastic pleomorphic xanthoastrocytoma that is resistant to treatment.


name: Conjunctival Carcinoma pT0 TNM Finding v8

description: Conjunctival carcinoma with no evidence of primary tumor. (from AJCC 8th Ed.)


name: Gastrointestinal Stromal Tumor Clinical TNM Finding v7

description: A clinical finding about one or more characteristics of gastrointestinal stromal tumor, following the rules of the TNM AJCC v7 classification system.


name: Idiopathic Cytopenias of Undetermined Significance

description: Cytopenia in one or more hematopoietic cell lineages that remains unexplained following thorough evaluation. The hematopoietic cell dysplasia is mild and does not fulfill the criteria for myelodysplastic syndrome, but the cytopenia may be severe. There is no evidence of clonal hematopoiesis or the variant allele frequency (VAF) is less that 2 percent. There is no other evidence of hematologic malignancy. It may progress to an overt myelodysplastic syndrome or other myeloid neoplasms such as acute myeloid leukemia, myeloproliferative neoplasm, or mast cell disorder.


name: Cerebral Infarction due to Embolism of Bilateral Vertebral Artery

description: Evidence of cerebral infarction due to an embolism of the bilateral vertebral artery.


name: Hodgkin's disease mixed cellularity stage III

description: Ann Arbor Classification: Stage III: Involvement of lymph node regions on both sides of the diaphragm (III), which also may be accompanied by extralymphatic extension in association with adjacent lymph node involvement (IIIE) or by involvement of the spleen (IIIS) or both (IIIE,S).


description: Evidence of pre-existing hypertensive chronic kidney disease complicating pregnancy in an unspecified trimester.


name: Thyroid Cancer pN0 TNM Finding v6 and v7

description: Thyroid cancer with no regional lymph node metastasis. (from AJCC 6th and 7th Eds.)


name: Carcinoma in situ of skin of other parts of face

description: Evidence of carcinoma in situ of the skin of other parts of face.


name: Grade 3 Nose Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


Prostate Cancer cT1c TNM Finding v7

description: Tumor identified by needle biopsy (e.g., because of elevated PSA). (from AJCC 7th Ed.)


name: Grade 3 Soft Tissue Infection NOS Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


name: Occlusion and Stenosis of Left Anterior Cerebral Artery

description: Evidence of occlusion and stenosis of left anterior cerebral artery.


Grade 3 Hyponatremia, CTCAE

description: 125-129 mmol/L symptomatic; 120-124 mmol/L regardless of symptoms


name: MET/Chromosome 7 Copy Number Ratio Finding

description: A genetic copy number finding indicating the ratio of the number of signals for a probe targeting the MET gene to the number of signals for a probe targeting chromosome 7.


Grade 3 Laryngeal Obstruction, CTCAE

description: Limiting self care ADL; stridor; endoscopic intervention indicated (e.g., stent, laser)


name: Ocular Adnexal Lymphoma pN3 TNM Finding v7

description: Involvement of peripheral lymph nodes not draining ocular adnexal region. (from AJCC 7th Ed.)


Grade 3 Dysphasia, CTCAE

description: Severe receptive or expressive characteristics; impairing ability to read, write or communicate intelligibly


Grade 2 Dysarthria, CTCAE

description: Moderate impairment of articulation or slurred speech


name: Recurrent Appendix Mucinous Adenocarcinoma

description: The reemergence of appendix mucinous adenocarcinoma after a period of remission.


Lipoprotein(a) Quantitative Trait Locus

description: A metabolic disorder caused by polymorphisms in the LPA gene that affect the number of kringle-4 repeats in the encoded protein, apolipoprotein(a) (apo(a)). The number of kringle-4 repeats are inversely correlated with apo(a) expression in the blood. Thus, forms of apo(a) with fewer repeats are expressed at elevated levels, which leads to increased concentrations of apo(a)-containing lipoprotein particles and an elevated risk for atherosclerosis, cardiovascular disease, and coronary artery disease.


name: Grade 5 Pancreas Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


name: Drug or Chemical Induced Diabetes Mellitus with Diabetic Peripheral Angiopathy with Gangrene

description: Evidence of drug or chemical induced diabetes mellitus with diabetic peripheral angiopathy with gangrene.


Benign squamous cell tumor

description: A non-metastasizing neoplasm composed of squamous cells. The neoplastic cells do not display malignant features.


Thyroid Cancer pT4b TNM Finding v6

description: Thyroid cancer with any size tumor invading the prevertebral fascia, or encasing the carotid artery or mediastinal vessels.


Surface Osteoma

description: An osteoma that arises from the surface of the bone.


name: Eyelid Carcinoma Pathologic Regional Lymph Nodes TNM Finding v8

description: A pathologic finding about one or more characteristics of eyelid carcinoma, following the rules of the TNM AJCC v8 classification system as they pertain to staging of regional lymph nodes.


name: iFGF23 Level Greater Than or Equal to 100 pg/mL

description: A finding indicating that the amount of the intact fibroblast growth factor 23 in a sample is greater than or equal to 100 pg/mL.


Endometriosis of thorax

description: A condition characterized by the presence of functioning endometrial tissue in the lung, pleura, chest wall, and/or diaphragm.


Part-Solid Nodule

description: Nodule with both ground-glass and solid components. The solid component corresponds to NO underlying normal anatomy, obscures the underlying lung structures and should measure at least 2 mm. The solid component should be measured in longest dimension.


Micronodular adrenal hyperplasia

description: Adrenal hyperfunction associated with multiple bilateral adrenal nodules, usually less than one centimeter in diameter.


name: Neonatal cerebral infarction, right side of brain

description: Evidence of neonatal cerebral infarction in the right side of brain.


name: Grade 5 Jejunum Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


Grade 5 Hypoparathyroidism, CTCAE

description: Death


name: Stage I Acral Lentiginous Melanoma AJCC v7

description: Stage I includes: IA: (T1a, N0, M0); IB: (T1b, N0, M0); (T2a, N0, M0).  T1a: Cutaneous melanoma with a tumor measuring 1.0 mm or less in thickness, without ulceration and mitosis less than 1/mm2.  T1b: Cutaneous melanoma with a tumor measuring 1.0 mm or less in thickness, with ulceration or mitoses equal to or more than 1/mm2. T2a: Cutaneous melanoma with a tumor measuring 1.01-2.0 mm in thickness, without ulceration.  N0: No regional lymph node metastases.  M0: No detectable evidence of distant metastases. (from AJCC 7th Ed.)


JC virus infection

description: An infection that is caused by JC virus.


Grade 5 Hepatic Failure, CTCAE

description: Death


Chief Complaint Present at Midday

description: The chief complaint is noted to primarily occur in the period on or around noon.


name: Intestinal Metaplasia of Bladder Urothelium


name: Other Specified Type of Carcinoma in Situ of Unspecified Breast

description: Evidence of other specified type of carcinoma in situ of unspecified breast not specified elsewhere.


Resectable Malignant Mesothelioma

description: Malignant mesothelioma that is amenable to surgical resection.


name: Unspecified Pre-Existing Hypertension Complicating Pregnancy, Second Trimester

description: Evidence of unspecified pre-existing hypertension complicating pregnancy in the second trimester.


Grade 1 Flashing Lights, CTCAE

description: Symptomatic but not limiting ADL


name: Fistula of intestine, excluding rectum and anus

description: An abnormal connection between the intestine and another epithelial-lined structure, but that does not include the rectum or anus.


name: Grade 1 Trachea Mucositis or Stomatitis by Functional or Symptomatic Classification, CTCAE


name: Pancreatic Undifferentiated Carcinoma with Rhabdoid Cells

description: An undifferentiated carcinoma that arises from the pancreas. It is characterized by the presence of rhabdoid cells.


name: Stage III Appendix Neuroendocrine Tumor AJCC v8

description: Stage III includes: (T1, N1, M0); (T2, N1, M0); (T3, N1, M0); (T4, N0, M0); (T4, N1, M0). T1: Tumor measuring 2 cm or less in greatest dimension. T2: Tumor measuring more than 2 cm but less than or equal to 4 cm. T3: Tumor measuring more than 4 cm or with subserosal invasion or involvement of the mesoappendix. T4: Tumor perforating the peritoneum or directly invading other adjacent organs or structures (excluding direct mural extension to adjacent subserosa of adjacent bowel), e.g., abdominal wall and skeletal muscle. N0: No regional lymph node metastasis. N1: Regional lymph node metastasis. M0: No distant metastasis. (AJCC 8th ed.)


name: Other Paralytic Syndrome following Non-Traumatic Intracerebral Hemorrhage Affecting Left Non-Dominant Side

description: Evidence of other paralytic syndrome following non-traumatic intracerebral hemorrhage affecting left non-dominant side not specified elsewhere.


name: Grade 2 Biliary Tree Common Bile Duct Intra-Operative Injury, CTCAE


Spinal enthesopathy

description: Evidence of spinal enthesopathy in the site unspecified.


name: Drug or Chemical Induced Diabetes Mellitus with Moderate Non-Proliferative Diabetic Retinopathy with Macular Edema, Unspecified Eye

description: Evidence of drug or chemical induced diabetes mellitus with moderate non-proliferative diabetic retinopathy with macular edema in an unspecified eye.


Abnormal Audiogram

description: A finding of significant hearing loss documented with audiometric testing.


Absent Breath Sounds

description: Absence of breath sounds noted during auscultation.


name: Childhood Acute Myeloid Leukemia with Abnormalities of Chromosome 5q

description: A rare acute myeloid leukemia that occurs in childhood and is characterized primarily by deletions of 5q.


Grade 3 Abducens Nerve Disorder, CTCAE

description: Severe symptoms; limiting self care ADL


name: Cerebral Infarction due to Thrombosis of Left Anterior Cerebral Artery

description: Evidence of cerebral infarction due to a thrombosis of the left anterior cerebral artery.


name: Conjunctival Melanoma cM1 TNM Finding v8

description: Conjunctival melanoma with distant metastasis. (from AJCC 8th Ed.)


Grade 4 Rectal Obstruction, CTCAE

description: Life-threatening consequences; urgent operative intervention indicated


name: Nodular Lymphocyte Predominant Hodgkin Lymphoma, Intrapelvic Lymph Nodes

description: Evidence of nodular lymphocyte predominant Hodgkin lymphoma in the intrapelvic lymph nodes.


name: Locally Advanced Skin Squamous Cell Carcinoma

description: A squamous cell carcinoma of the skin that has spread from its original site of growth to nearby tissues or lymph nodes.


name: Adverse Event Associated with the Gastrointestinal System


name: Grade 1 Lower Extremity Vein Intra-Operative Injury, CTCAE


Generalised illness

description: A pathologic process that has spread from its original site of growth to multiple distant anatomic sites.


endometritis following abortion

description: Endometritis that develops following an abortion.


name: Grade 4 Herpes Simplex Reactivation, CTCAE

description: Life-threatening consequences; urgent intervention indicated


name: Conjunctival Reactive Lymphoid Hyperplasia

description: A polyclonal proliferation of lymphoid tissue in the conjunctiva that typically occurs in young adults. It usually presents as a unilateral, red or orange, painless swelling and is probably caused by chronic antigen stimulation. (WHO 2018)


name: Small Intestine Cancer pT0 TNM Finding v7

description: Small intestine cancer with no evidence of primary tumor. (from AJCC 7th Ed.)


Supratentorial Glioblastoma

description: A glioblastoma that occurs in the supratentorial region.


name: HPV-Mediated (p16-Positive) Oropharyngeal Cancer cN2 TNM Finding v8

description: HPV-mediated (p16-positive) oropharyngeal cancer with contralateral or bilateral lymph node metastasis, none larger than 6 cm. (from AJCC 8th Ed.)


name: Severe major depression, single episode, with psychotic features

description: Evidence of major depressive disorder that is a single episode and is severe with psychotic features.


Ostomy Site Pain

description: Pain at the site of an ostomy.


name: Duodenum and Ampulla of Vater Neuroendocrine Tumor pT4 TNM Finding v8

description: Duodenum and ampulla of Vater neuroendocrine tumor invading the visceral peritoneum (serosa) or other organs. (from AJCC 8th Ed.)


name: Grade 3 Upper Extremity Artery Injury, CTCAE


name: Occlusion and Stenosis of Bilateral Carotid Arteries

description: Evidence of occlusion and stenosis of bilateral carotid arteries.


Metastatic Malignant Germ Cell Tumor

description: A malignant germ cell tumor that has spread from its original site of growth to another anatomic site.


Benign vascular neoplasm

description: A mesenchymal neoplasm that arises from vascular tissue usually of the skin. It is characterized by the presence of vascular channel formation and endothelial cells. There is no evidence of atypical or malignant cytological and architectural features, invasive features, or metastases.


name: Refractory Mixed Phenotype Acute Leukemia

description: Mixed phenotype acute leukemia that does not respond to treatment.


Gastric Perforation, CTCAE

description: A disorder characterized by a rupture in the stomach wall.


REVESZ SYNDROME (disorder)

description: An autosomal dominant form of dyskeratosis congenita, caused by mutation(s) in the TINF2 gene, encoding TERF1-interacting nuclear factor 2. It is a fatal disease associated with exudative retinopathy and bone marrow failure.


name: Grade 2 Colon Stricture or Stenosis, CTCAE


name: Post-Immunization Arthropathy, Right Wrist

description: Evidence of post-immunization arthropathy in the right wrist.


name: Grade 4 Ileum Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


name: Anaemias due to disorders of glutathione metabolism

description: Anemia resulting from an abnormality of glutathione deficiency.


Stage IIB Merkel Cell Carcinoma AJCC v7

description: Stage IIB includes: T2/T3, cN0, M0.  T2: Primary tumor greater than 2 cm but not more than 5 cm in maximum dimension.  T3: Primary tumor over 5 cm in maximum dimension.  cN0: No regional lymph node metastasis by clinical examination.  M0: No distant metastasis.  (AJCC 7th Ed.)


Grade 1 Testicular Disorder, CTCAE

description: Asymptomatic; clinical or diagnostic observations only; intervention not indicated


name: Grade 1 Inferior Vena Cava Intra-Operative Injury, CTCAE


Substance-Induced Sexual Dysfunction

description: A disorder characterized by clinically significant sexual dysfunction (including impaired desire, impaired arousal, impaired orgasm, or sexual pain) that is fully explained by substance use.


Pelvic Cancer

description: A primary or metastatic malignant neoplasm that affects the organs and structures of the pelvis.


name: Synchronous Nodules with Dominant Lesion(s)

description: A finding of multiple pulmonary nodules in which radiologic imaging demonstrates the presence of a dominant lesion.


name: Grade 2 Cecum Intra-Operative Injury, CTCAE


name: Adult TdT Positive Acute Lymphoblastic Leukemia

description: TdT positive acute lymphoblastic leukemia that occurs during adulthood.


name: Type 2 Diabetes Mellitus with Diabetic Peripheral Angiopathy with Gangrene

description: Evidence of type 2 diabetes mellitus with diabetic peripheral angiopathy with gangrene.


Chief Complaint Present in the Evening

description: The chief complaint is noted to primarily occur after sunset but before bedtime.


name: Choroidal and Ciliary Body Melanoma pT2 TNM Finding v8

description: Choroidal and ciliary body melanoma, tumor size category 2. (from AJCC 8th Ed.)


Grade 2 Gallbladder Pain, CTCAE

description: Moderate pain; limiting instrumental ADL


name: Ampulla of Vater Cancer pTX TNM Finding v8

description: Ampulla of Vater cancer in which the primary tumor cannot be assessed. (from AJCC 8th Ed.)


Cocaine abuse, in remission

description: Evidence of cocaine abuse, in remission.


name: Perihilar Bile Duct Cancer pT2a TNM Finding v8

description: Perihilar bile duct cancer with tumor invading beyond the wall of the bile duct to surrounding adipose tissue. (from AJCC 8th Ed.)


Grade 2 Leukoencephalopathy, CTCAE

description: Moderate symptoms; focal T2/FLAIR hyperintensities, involving periventricular white matter extending into centrum semiovale or involving 1/3 to 2/3 of susceptible areas of cerebrum +/- moderate increase in SAS and/or moderate ventriculomegaly


name: Other Associated with the Heart in General, CTCAE


name: Grade 5 Neonatal Coagulation Disorder, AE

description: A coagulation disorder adverse event in a newborn which results in death.


name: Urothelial (Transitional Cell) Carcinoma of the Prostate pT4 TNM Finding v7

description: Urothelial (transitional cell) carcinoma of the prostate with tumor invading other adjacent organs (invasion of the bladder). (from AJCC 7th Ed.)


name: Conjunctival Melanoma pT3b TNM Finding v8

description: Conjunctival melanoma with tumor of any size invading the eyelid. (from AJCC 8th Ed.)


name: Grade 2 Cecum or Appendix Hemorrhage, CTCAE


KATP-Associated Hyperinsulinism

description: Hyperinsulinism caused by non-functional beta-cell ATP-sensitive potassium channels due to inactivating mutation(s) in either the ABCC8 or KCNJ11 gene.


Third Ventricle Germinoma

description: A germinoma that arises from the third ventricle.


name: Grade 1 Atrioventricular Block First Degree, CTCAE

description: Asymptomatic, intervention not indicated


Soft Tissue Sarcoma TNM Finding v8

description: A finding about one or more characteristics of soft tissue sarcoma, following the rules of the TNM AJCC v8 classification system. This classification system applies to soft tissue sarcomas that arise in the following areas: head and neck, trunk and extremities, gastrointestinal tract, genitourinary tract, viscera and retroperitoneum, gynecologic sites, breast, lung, pleura, mediastinum, and other unusual histologies and sites. It does not apply to desmoid tumor/deep fibromatosis (no AJCC staging system available) and Kaposi sarcoma (no AJCC staging system available; AIDS Clinical Trials Group system TIS (tumor, immune system, systemic illness) staging may be used). (from AJCC 8th Ed.)


name: Grade 3 Peripheral Nerve Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


name: Rheumatoid Vasculitis with Rheumatoid Arthritis of Left Hip

description: Evidence of rheumatoid vasculitis with rheumatoid arthritis of left hip.


description: Evidence of spastic hemiplegia affecting left dominant side.


Pulmonary Fibrosis, CTCAE

description: A disorder characterized by the replacement of the lung tissue by connective tissue, leading to progressive dyspnea, respiratory failure or right heart failure.


name: Stage IIA Fallopian Tube Cancer AJCC v6 and v7

description: Stage IIA includes: T2a, N0, M0.  T2a: Extension and/or metastasis to the uterus and/or ovaries.  N0: No regional lymph node metastasis.  M0: No distant metastasis.  (AJCC 6th and 7th eds.)


name: Grade 2 Phlebitis Including Superficial Thrombosis, CTCAE


Grade 1 Concentration Impairment, CTCAE

description: Mild inattention or decreased level of concentration


name: Distal Bile Duct Cancer pT4 TNM Finding v7

description: Distal bile duct cancer with tumor involving the celiac axis or the superior mesenteric artery. (from AJCC 7th Ed.)


name: Cerebral Infarction due to Embolism of Unspecified Anterior Cerebral Artery

description: Evidence of cerebral infarction due to an embolism of an unspecified anterior cerebral artery.


name: Carcinoma in Situ of Other and Unspecified Digestive Organs

description: Evidence of carcinoma in situ of other and unspecified digestive organs.


name: Radiating Chest Pain Along Anterior Axillary Line

description: The location of the radiating chest pain is along an imaginary vertical line that descends along the lateral aspect of the chest wall originating from the armpit.


Grade 4 Small Intestine Ulcer, CTCAE

description: Life-threatening consequences; urgent operative intervention indicated


name: Grade 5 Urinary Tract Infection NOS with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


Liposarcoma recurrent

description: The reemergence of liposarcoma after a period of remission.


name: Primary Mediastinal (Thymic) Large B-Cell Lymphoma, Intrapelvic Lymph Nodes

description: Evidence of primary mediastinal (thymic) large B-cell lymphoma in the intrapelvic lymph nodes.


T2b TNM Finding

description: A general term that refers to a TNM finding of a primary tumor growth beyond the level of in situ cancer, minimal subepithelial invasion, or minimal greatest diameter. The definition of T2b TNM finding depends on the specific type of cancer that it refers to; for example, for kidney cancer it refers to a primary tumor that measures more than 10 cm in greatest dimension, and is limited to the kidney; for bladder cancer it refers to a primary tumor that invades the deep muscularis propria (outer half); for cervical cancer it refers to a primary tumor that invades beyond the uterus but not to the pelvic wall or to the lower third of vagina and there is parametrial invasion.


Progesterone Receptor Negative

description: An indication that progesterone receptor (PRG; PR) expression has not been detected in a sample.


Rheumatoid Bursitis, Right Wrist

description: Evidence of rheumatoid bursitis in the right wrist.


Neoplasm of Uncertain Histogenesis

description: A benign or malignant, primary or metastatic neoplasm with uncertain histogenesis.


Cervical Cancer cT1 TNM Finding v7

description: Cervical cancer confined to uterus (extension to corpus should be disregarded). (from AJCC 7th Ed.)


name: Merkel Cell Polyoma Virus-Negative Merkel Cell Carcinoma

description: A Merkel cell carcinoma that is not associated with Merkel cell polyoma virus infection.


name: Primary Cutaneous B-Cell/T-Cell (Non-MF/SS) Lymphoma M0 TNM Finding v8

description: No evidence of extracutaneous non-lymph node disease. (from AJCC 8th Ed.)


Metaplastic Synovial Cyst

description: A cyst lined by tissue that resembles synovial villi.


name: Overlapping malignant neoplasm of stomach

description: Evidence of a malignant neoplasm of overlapping sites of the stomach.


Grade 1 Hypopituitarism, CTCAE

description: Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated


description: Evidence of hypertensive heart disease with heart failure.


name: Grade 1 Lower Extremity Artery Injury, CTCAE


name: Refractory Fallopian Tube High Grade Serous Adenocarcinoma

description: Fallopian tube high-grade serous adenocarcinoma that is resistant to treatment.


Paratesticular Squamous Cell Carcinoma

description: An extremely rare squamous cell carcinoma that arises from the paratesticular structures.


name: Grade 4 Duodenum Infection with Unknown Absolute Neutrophil Count, CTCAE


name: Breast Cancer pN2a TNM Finding v6 and v7

description: Breast cancer with metastasis in 4 to 9 axillary lymph nodes (at least 1 tumor deposit greater than 2.0 mm). (from AJCC 6th and 7th Eds.)


Recurrent Myeloid Sarcoma

description: The reemergence of myeloid sarcoma after a period of remission.


Assault

description: A physical attack.


name: Nodular Lymphocyte Predominant Hodgkin Lymphoma, Lymph Nodes of Axilla and Upper Limb

description: Evidence of nodular lymphocyte predominant Hodgkin lymphoma in the lymph nodes of axilla and upper limb.


name: Diffuse Glioneuronal Tumor with Oligodendroglioma-Like Features and Nuclear Clusters

description: A provisional tumor entity described in the supratentorial brain and characterized by a distinct DNA methylation profile and monosomy of chromosome 14. It is composed of small to medium-sized cells showing perinuclear oligodendroglioma-like haloes, scattered multinucleated cells, and nuclear clusters composed of large pleomorphic nuclei. Most cases have been reported in pediatric patients.


name: Grade 3 Larynx Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


name: Exocrine Pancreatic Cancer pN1 TNM Finding v6

description: Exocrine pancreatic cancer with regional lymph node metastasis. (from AJCC 6th Ed.)


Vaccination Complication, CTCAE

description: A disorder that occurs after the injection of a substance with antigenic properties, administered to activate the immune system.


name: Treatment related acute myeloid leukaemia

description: An acute myeloid leukemia arising as a result of the mutagenic effect of chemotherapy agents and/or ionizing radiation.  (WHO, 2001)


Breast Cancer pN3c TNM Finding v8

description: Breast cancer with metastases in ipsilateral supraclavicular lymph nodes. (from AJCC 8th Ed.)


name: Grade 2 Peripheral Nerve Infection with Unknown Absolute Neutrophil Count, CTCAE


name: Appendix Neuroendocrine Tumor cM1 TNM Finding v8

description: Appendix neuroendocrine tumor with distant metastasis. (from AJCC 8th Ed.)


name: Grade 3 Bladder Stricture or Stenosis, CTCAE


Grade 1 Gastritis, CTCAE

description: Asymptomatic; clinical or diagnostic observations only; intervention not indicated


name: Unspecified B-Cell Lymphoma, Lymph Nodes of Head, Face, and Neck

description: Evidence of unspecified B-cell lymphoma in the lymph nodes of head in the face in the and neck.


Transitional cell carcinoma in situ

description: A lesion in which the surface epithelium of the bladder or the renal pelvis and ureter contains transitional cells which display malignant cytologic characteristics.  There is no evidence of stromal invasion.


name: Exocrine Pancreatic Cancer Pathologic Regional Lymph Nodes TNM Finding v6

description: A pathologic finding about one or more characteristics of exocrine pancreatic cancer, following the rules of the TNM AJCC v6 classification system as they pertain to staging of regional lymph nodes.


name: Grade 3 Upper Airway Infection NOS with Unknown Absolute Neutrophil Count, CTCAE


name: Ann Arbor Stage IV AIDS-Related Lymphoma

description: Ann Arbor Classification: Stage IV: Diffuse or disseminated involvement of one or more extralymphatic organs, with or without associated lymph node involvement; or isolated extralymphatic organ involvement in the absence of adjacent regional lymph node involvement, but in conjunction with disease in distant site(s); or any involvement of the liver or bone marrow, lungs (other than by direct extension from another site), or cerebrospinal fluid.


name: Grade 1 Nasal Cavity and Paranasal Sinus Reactions, CTCAE


name: Hodgkin Lymphoma, Unspecified, Intra-abdominal Lymph Nodes

description: Evidence of unspecified Hodgkin lymphoma in the intra-abdominal lymph nodes.


Ureteric Anastomotic Leak, CTCAE

description: A finding of leakage due to breakdown of a ureteral anastomosis (surgical connection of two separate anatomic structures).


name: Stage III Ampulla of Vater Neuroendocrine Tumor AJCC v8

description: Stage III includes: (T4, N0, M0); (Any T, N1, M0). T4: Tumor invading the visceral peritoneum (serosa) or other organs. N0: No regional lymph node metastasis. N1: Regional lymph node metastasis. M0: No distant metastasis. (AJCC 8th ed.)


Myasthenia Gravis, CTCAE

description: A disorder characterized by weakness and rapid fatigue of any of the skeletal muscles.


Tracheal Mucositis, CTCAE

description: A disorder characterized by an inflammation or ulceration involving the mucous membrane of the trachea.


name: Peripheral T-Cell Lymphoma, not Classified, Extranodal and Solid Organ Sites

description: Evidence of unclassified peripheral T-cell lymphoma in the extranodal and solid organ sites.


Psychosis, CTCAE

description: A disorder characterized by personality change, impaired functioning, and loss of touch with reality. It may be a manifestation of schizophrenia, bipolar disorder or brain tumor.


name: Nasal Cavity and Ethmoid Sinus Cancer pT4a TNM Finding v6

description: Nasal cavity and ethmoid sinus cancer with tumor invading any of the following: anterior orbital contents, skin of nose or cheek, minimal extension to anterior cranial fossa, pterygoid plates, sphenoid or frontal sinuses. (from AJCC 6th Ed.)


Grade 1 Creatinine Increased, CTCAE

description: >ULN-1.5 x ULN


name: Aggressive Systemic Mastocytosis with an Associated Germ Cell Tumor

description: Aggressive systemic mastocytosis associated with a germ cell tumor.


name: Other specified neoplasms of uncertain behavior of lymphoid, hematopoietic and related tissue

description: Evidence of other specified neoplasms of uncertain behavior of lymphoid, hematopoietic and related tissue not specified elsewhere.


name: Grade 4 Stenosis of Gastrointestinal Stoma, CTCAE

description: Life-threatening consequences; urgent operative intervention indicated


Grade 2 Tinnitus, CTCAE

description: Moderate symptoms; limiting instrumental ADL


name: Grade 5 Bladder Infection with Unknown Absolute Neutrophil Count, CTCAE


Stage IIIC Appendix Carcinoma AJCC v7

description: Stage IIIC includes: Any T, N2, M0. N2: Metastasis in four or more regional lymph nodes.  M0: No distant metastasis.  (AJCC 7th ed.)


name: Drug or Chemical Induced Diabetes Mellitus with Proliferative Diabetic Retinopathy with Macular Edema, Right Eye

description: Evidence of drug or chemical induced diabetes mellitus with proliferative diabetic retinopathy with macular edema in the right eye.


Stage III Gallbladder Cancer AJCC v6

description: Stage III includes: (T4, Any N, M0).  T4: Tumor invades main portal vein or hepatic artery or invades multiple extrahepatic organs or structures. (AJCC 6th ed.)


name: Complete Response with Incomplete Platelet Recovery

description: The disappearance of all signs of cancer in response to treatment, accompanied by incomplete platelet recovery (platelet count is less than 100,000/uL).


name: Grade 5 Spermatic Cord Anastomotic Leak, CTCAE

description: Death


name: Carcinoma in Situ of Other and Unspecified Genital Organs

description: Evidence of carcinoma in situ of other and unspecified genital organs.


name: Pathologic Stage IIB Esophageal Adenocarcinoma AJCC v8

description: Stage IIB includes: (T1, N1, M0, Any G); (T3, N0, M0, Any G). T1: Tumor invades the lamina propria, muscularis mucosae, or submucosa. T3: Tumor invades adventitia. N0: No regional lymph node metastasis. N1: Tumor with metastasis in one or two regional lymph nodes. M0: No distant metastasis. (AJCC 8th ed.)


Bartholin Gland Hyperplasia

description: Nodular/lobular proliferation of normal Bartholin gland tissue and ducts.


Acquired arteriovenous aneurysm

description: An arteriovenous fistula, the cause of which is not present at birth.


name: Grade 3 Blood Corticotrophin Decreased, CTCAE

description: Hospitalization indicated


MITF Pathway Activated

description: A finding indicating that the MITF signaling pathway is activated.


Grade 4 Anemia, CTCAE

description: Life-threatening consequences; urgent intervention indicated


Grade 1 Retinopathy, CTCAE

description: Asymptomatic; clinical or diagnostic observations only


Grade 5 Encephalopathy, CTCAE

description: Death


ALK Gene Fusion Negative

description: An indication that an ALK fusion gene has not been detected in a sample.


name: Grade 4 Peripheral Motor Nerve NOS Intra-Operative Injury, CTCAE


name: Arthropathy following Intestinal Bypass, Unspecified Hand

description: Evidence of arthropathy following intestinal bypass in an unspecified hand.


name: Carcinoma of the Lacrimal Gland Clinical Distant Metastasis TNM Finding v7

description: A clinical finding about one or more characteristics of carcinoma of the lacrimal gland, following the rules of the TNM AJCC v7 classification system as they pertain to distant metastases.


Lung Cancer pT4 TNM Finding v6

description: Lung cancer with invasion of the mediastinum, heart, great vessels, trachea, esophagus, vertebral body or carina, or presence of separate tumor nodules within a same lobe, or the presence of a malignant pleural effusion. Although most pleural effusions associated with lung cancer are due to tumor, there are a few patients in whom multiple cytopathologic examinations of the pleural fluid are negative for tumor. In these cases, the fluid is non-bloody and is not an exudate. Such patients may be further evaluated with videothoracoscopy and direct pleural biopsy. When these elements and clinical judgment dictate that the effusion is not related to the tumor, the effusion should be excluded as a staging element. (from AJCC 6th Ed.)


Bronchopleural Fistula

description: An abnormal communication between a bronchus and the pleural cavity.


Refractory Biliary Tract Carcinoma

description: Biliary tract carcinoma that is resistant to treatment.


name: Malignant Neoplasm of Nipple and Areola, Left Male Breast

description: Evidence of a malignant neoplasm of the nipple and areola in the left male breast.


Body Mass Index 70 or Greater, Adult

description: Evidence of a body mass index of 70 or greater in the adult.


name: Carcinoma of the Lacrimal Gland pN1 TNM Finding v7

description: Carcinoma of the lacrimal gland with regional lymph node metastasis. (from AJCC 7th Ed.)


Bigeminy, CTCAE

description: Premature heartbeats alternating regularly with normal beats. It can be associated with hypoxia, ischemia, acute myocardial infarction, and medication overdose.


Primary Raynaud Phenomenon

description: Raynaud phenomenon without a known underlying autoimmune disorder.


Gallbladder Mucinous Cystic Neoplasm

description: An epithelial, usually multiloculated neoplasm arising from the gallbladder. It occurs predominantly in females. Signs and symptoms include abdominal mass, abdominal pain, and jaundice. Morphologically, the cystic spaces are lined by columnar epithelium and contain mucinous or serous fluid.


Advanced Melanoma

description: Melanoma that has spread extensively to other anatomic sites or is no longer responding to treatment.


Grade 3 Gallbladder Obstruction, CTCAE

description: Symptomatic and severely altered GI function; tube feeding, TPN or hospitalization indicated; non-emergent operative intervention indicated


name: Sedative, hypnotic or anxiolytic abuse with withdrawal with perceptual disturbance

description: Evidence of sedative, hypnotic or anxiolytic abuse with withdrawal with perceptual disturbance.


name: Grade 4 Biliary Tree Left Hepatic Duct Intra-Operative Injury, CTCAE


name: Skin and Subcutaneous Tissue Disorders - Other, Specify, CTCAE


name: Hypopharyngeal Cancer pNX TNM Finding v8

description: Hypopharyngeal cancer in which the regional lymph nodes cannot be assessed. (from AJCC 8th Ed.)


name: Grade 1 Vein NOS Intra-Operative Injury, CTCAE


name: Prostate Adenocarcinoma without Neuroendocrine Differentiation

description: A prostate adenocarcinoma characterized by the absence of focal or diffuse neuroendocrine differentiation.


name: Metastatic Digestive System Neuroendocrine Tumor G1

description: Digestive system neuroendocrine tumor G1 that has spread to other anatomic sites.


Grade 1 Uterine Anastomotic Leak, CTCAE

description: Asymptomatic diagnostic finding; intervention not indicated


name: Grade 4 Female Genital Tract Fistula, CTCAE


name: Peripheral Nerve Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


name: Grade 2 Foreign Body Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


Breast Cancer pN1b TNM Finding v8

description: Breast cancer with metastases in ipsilateral internal mammary sentinel nodes, excluding ITCs. (from AJCC 8th Ed.)


Grade 5 Hypoglycemia, CTCAE

description: Death


Adenocarcinoma, Oxyphilic

description: An adenocarcinoma characterized by the presence of large malignant epithelial cells with abundant granular eosinophilic cytoplasm (oncocytes). Representative examples include thyroid gland oncocytic follicular carcinoma, oncocytic breast carcinoma, and salivary gland oncocytic carcinoma.


Non-Neoplastic Uveal Disorder

description: A non-neoplastic disorder that affects the uvea.


name: Hodgkin's disease mixed cellularity recurrent

description: The reemergence of mixed cellularity classic Hodgkin lymphoma after a period of remission.


name: Grade 2 Abdomen Soft Tissue Necrosis, CTCAE


Pancreatic Acinar Cell Neoplasm

description: An epithelial neoplasm that arises from the exocrine pancreas.  It is characterized by the presence of neoplastic cells that resemble acinar cells and produce pancreatic exocrine enzymes.  The vast majority are carcinomas.


name: Grade 3 Brachial Plexus Intra-Operative Injury, CTCAE


Lymphangiomatosis

description: A lymphangioma affecting several anatomic sites.


name: Rheumatoid Arthritis of Unspecified Site with Involvement of Organs and Systems

description: Evidence of rheumatoid arthritis of unspecified site with involvement of organs and systems.


name: Esophagus and Esophagogastric Junction Cancer pT3 TNM Finding v8

description: Esophagus and esophagogastric junction cancer with tumor invading adventitia. (from AJCC 8th Ed.)


Grade 2 Colonic Ulcer, CTCAE

description: Symptomatic; altered GI function


name: Displacement of Heart Valve Prosthesis, Subsequent Encounter

description: Evidence of displacement of heart valve prosthesis, subsequent encounter.


name: Diabetes Mellitus due to Underlying Condition with Hyperosmolarity without Non-Ketotic Hyperglycemic-Hyperosmolar Coma

description: Evidence of diabetes mellitus due to underlying condition with hyperosmolarity without non-ketotic hyperglycemic-hyperosmolar coma.


Colorectal Cancer pN1a TNM Finding v8

description: Colorectal cancer in which one regional lymph node is positive. (from AJCC 8th Ed.)


Phantom pain

description: Painful sensation related to a limb or an organ that is removed from or is not physically part of the body.


Urethral Cancer pN1 TNM Finding v7

description: Urethral cancer with metastasis in a singe lymph node 2 cm or less in greatest dimension. (from AJCC 7th Ed.)


name: Metastatic Bladder Giant Cell Urothelial Carcinoma

description: Bladder giant cell urothelial carcinoma that has spread to another anatomic site.


Radiologic Response

description: An evaluation of the radiologic response of the disease to the therapy.


name: Bipolar Disorder, Current Episode Mixed, Severe, without Psychotic Features

description: Evidence of bipolar disorder, current episode mixed, severe without psychotic features.


Spine Cancer pT0 TNM Finding v8

description: Spine cancer without evidence of primary tumor. (from AJCC 8th Ed.)


Melanosis

description: A benign congenital or acquired lesion that arises from mucosal sites and is characterized by melanin pigment deposition in the basilar keratinocytes. It may be associated with a slight proliferation of junctional melanocytes. It presents as a single or multiple pigmented macules or patches in the external genitalia, anorectal region, distal urinary tract, and oral cavity.


Unresectable Melanoma

description: Melanoma which is not amenable to surgical resection.


name: Grade 1 Cranial Nerve IV Neuropathy, CTCAE


PSA Level Greater than 0.2

description: A blood concentration of prostate specific antigen greater than 0.2 ng/mL.


Alcohol-Related Carcinoma

description: A carcinoma that is caused by alcohol abuse.


name: Retinoblastoma by AJCC v8 Clinical Stage

description: A term that refers to the clinical staging of retinoblastoma according to the American Joint Committee on Cancer, 8th edition.


name: Kidney Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


name: Esophagus and Esophagogastric Junction Cancer pT4 TNM Finding v7

description: Esophagus and esophagogastric junction cancer with tumor invading adjacent structures. (from AJCC 7th Ed.)


Appendiceal Carcinoma TNM Finding v7

description: A finding about one or more characteristics of appendiceal carcinoma, following the rules of the TNM AJCC v7 classification system.


Chronic pulmonary embolism

description: Persistent and long-standing pulmonary embolism.


BRAF V600E Negative

description: An indication that expression of the BRAF V600E mutation has not been detected in a sample.


name: Maxillary Sinus Cancer Clinical TNM Finding v7

description: A clinical finding about one or more characteristics of maxillary sinus cancer, following the rules of the TNM AJCC v7 classification system.  The assessment is based on inspection and palpation, including examination of the orbits, nasal and oral cavities, and nasopharynx, and neurologic examination of the cranial nerves.  Nasal endoscopy with rigid or fiberoptic flexible instruments is recommended.  Radiologic assessment with magnetic resonance imaging (MRI) or computed tomography (CT) is mandatory for accurate pretreatment staging of malignant tumors of the sinuses. (from AJCC 7th Ed.)


Visceral edema

description: Accumulation of an excessive amount of watery fluid in the visceral tissues. Symptoms include abdominal pain, nausea, vomiting, and diarrhea.


name: Intermediate Grade B-Cell Non-Hodgkin's Lymphoma


Liver Non-Epithelial Neoplasm

description: A benign or malignant non-epithelial neoplasm that affects the liver.


name: Grade 1 Vaginal Stenosis and Length, CTCAE


name: Atherosclerosis of Native Arteries of Left Leg with Ulceration of Other Part of Lower Left Leg

description: Evidence of atherosclerosis of native arteries of left leg with ulceration of other part of lower left leg.


name: undifferentiated carcinoma of anal canal

description: A usually aggressive malignant epithelial neoplasm that arises from the anal canal.  It is composed of malignant cells which do not display evidence of glandular or squamous differentiation.


Other dystonia

description: Evidence of other dystonia not specified elsewhere.


Grade 4 Radiculitis, CTCAE

description: Life-threatening consequences; urgent intervention indicated


Grade 4 Peripheral Ischemia, CTCAE

description: Life-threatening consequences; evidence of end organ damage; urgent operative intervention indicated


Hematuria, CTCAE

description: A disorder characterized by laboratory test results that indicate blood in the urine.


name: Peripheral T-Cell Lymphoma, not Classified, Lymph Nodes of Multiple Sites

description: Evidence of unclassified peripheral T-cell lymphoma in the lymph nodes of multiple sites.


Female Reproductive System Carcinoma

description: A malignant neoplasm that arises from the epithelium of any part of the female reproductive system. Representative examples include ovarian carcinoma, cervical carcinoma, and endometrial carcinoma.


Grade 2 Kidney Anastomotic Leak, CTCAE

description: Symptomatic; medical intervention indicated


name: Bile Duct Mucinous Cystic Neoplasm with Intermediate Grade Intraepithelial Neoplasia

description: A non-invasive mucinous cystic neoplasm that arises from the intrahepatic or extrahepatic bile ducts.  It is characterized by the presence of moderate atypia.


name: Invasive Bladder Poorly Differentiated Urothelial Carcinoma

description: Invasive bladder urothelial carcinoma that lacks the morphological features indicating urothelial origin. Immunohistochemical studies are required to demonstrate the urothelial lineage in these tumors.


Stage IIA Merkel Cell Carcinoma AJCC v7

description: Stage IIA includes: T2/T3, pN0, M0.  T2: Primary tumor greater than 2 cm but not more than 5 cm in maximum dimension.  T3: Primary tumor over 5 cm in maximum dimension.  pN0: No regional lymph node metastasis by pathologic examination.  M0: No distant metastasis.  (AJCC 7th Ed.)


BRCA Gene Mutation Negative

description: A genetic finding indicating that BRCA family gene mutations have not been detected in a sample.


Sarcoma of the Orbit TNM Finding v7

description: A finding about one or more characteristics of sarcoma of the orbit, following the rules of the TNM AJCC v7 classification system.  No stage grouping is presently recommended for sarcoma of the orbit.  (from AJCC 7th Ed.)


Rheumatoid Nodule, Unspecified Wrist

description: Evidence of rheumatoid nodule in an unspecified wrist.


Post-Immunization Arthropathy, Left Hip

description: Evidence of post-immunization arthropathy in the left hip.


Uterine Pain

description: A painful sensation in the uterus.


name: Pathologic Stage IA Cutaneous Melanoma AJCC v8

description: Stage IA includes: (T1a, N0, M0); (T1b, N0, M0). T1a: Tumor measuring less than 0.8 mm in thickness. Ulceration status: Without ulceration. T1b: Tumor measuring less than 0.8 mm in thickness with ulceration, or 0.8-1.0 mm with or without ulceration. N0: No regional lymph node metastasis detected. Presence of in-transit, satellite, and/or microsatellite metastases: No. M0: No evidence of distant metastasis. LDH level is not applicable. (AJCC 8th ed.)


name: Grade 5 Lymphatic Infection with Unknown Absolute Neutrophil Count, CTCAE


name: Anal or Perianal Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


name: Appendix Neuroendocrine Tumor pM1b TNM Finding v8

description: Appendix neuroendocrine tumor with metastasis in at least one extrahepatic site (e.g., lung, ovary, nonregional lymph node, peritoneum, bone). (from AJCC 8th Ed.)


Breast Cancer Clinical TNM Finding v6

description: A clinical finding about one or more characteristics of breast cancer, following the rules of the TNM AJCC v6 classification system. TNM clinical findings are based on information obtained prior to the first definitive treatment through physical examination, diagnostic imaging, endoscopy, biopsy or laboratory testing.


name: Grade 1 Electrocardiogram QT Corrected Interval Prolonged, CTCAE

description: Average QTc 450-480 ms


name: Benign neoplasm of other specified parts of central nervous system

description: Evidence of benign neoplasm of other specified parts of central nervous system.


name: Grade 4 Extrapyramidal and Involuntary Movement and Restlessness, CTCAE


MYC Gene Amplification Negative

description: An indication that amplification of the MYC gene was not detected in a sample.


Hemoglobin Beta Genotype Finding

description: A genetic finding indicating the genotype composition in a subject for the HBB gene that is located on chromosome 16 and encodes hemoglobin subunit beta. There is one maternal copy and one paternal copy of the HBB gene (B/B).


Stage IIB Gallbladder Cancer AJCC v8

description: Stage IIB includes: T2b, N0, M0. T2b: Tumor invading the perimuscular connective tissue on the hepatic side, with no extension into the liver. N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 8th ed.)


name: Follicular Lymphoma Grade III, Unspecified, Lymph Nodes of Multiple Sites

description: Evidence of unspecified follicular lymphoma grade III in the lymph nodes of multiple sites.


name: Gastrointestinal Disorders - Other, Specify, CTCAE


name: Metastatic Clear Cell (Glycogen-Rich) Urothelial Carcinoma

description: Clear cell (glycogen-rich) urothelial carcinoma that has spread to another anatomic site.


Colorectal Cancer pT4a TNM Finding v6

description: Colorectal cancer which directly invades other organs or structures.


name: Direct Infection of Right Elbow in Infectious and Parasitic Diseases Classified Elsewhere

description: Evidence of direct infection of right elbow in infectious and parasitic diseases classified elsewhere.


name: Recurrent Accelerated Phase Chronic Myeloid Leukemia, BCR-ABL1 Positive

description: The reemergence of accelerated phase chronic myeloid leukemia, BCR-ABL1 positive after a period of remission.


name: Maxillary Sinus Cancer pNX TNM Finding v6 and v7

description: Maxillary sinus cancer in which the regional lymph nodes cannot be assessed. (from AJCC 6th and 7th Eds.)