Cervical Cancer pTX TNM Finding v9

description: Cervical cancer in which the primary tumor cannot be assessed. (from AJCC 9th Ed.)


Esophagus Necrosis, CTCAE

category: biolink:PhenotypicFeature biolink:DiseaseOrPhenotypicFeature biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing


Percent Host Cell Post-Engraftment

description: The ratio of host-derived cells compared to total cells in a blood cell count following transplantation.


Grade 3 Rectal Pain, CTCAE

description: Severe pain; limiting self care ADL


Gastric Cancer pMX TNM Finding v6

description: Gastric cancer in which distant metastasis cannot be assessed. (from AJCC 6th Ed.)


name: Drug or Chemical Induced Diabetes Mellitus with Mild Non-Proliferative Diabetic Retinopathy without Macular Edema, Bilateral

category: biolink:Disease biolink:DiseaseOrPhenotypicFeature biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing

description: Evidence of drug or chemical induced diabetes mellitus with mild non-proliferative diabetic retinopathy without macular edema that is bilateral.


PTEN Deficiency

description: A condition of decreased or absent presence or activity of phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN, which is associated with multiple hamartoma syndrome (Cowden syndrome) and increased risk for development of several types of malignant cancers, including head and neck, breast, lung and prostate cancer and glioblastoma.


name: Refractory Malignant Male Reproductive System Neoplasm

description: Malignant male reproductive system neoplasm that is resistant to treatment.


name: Urethra Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


Cutaneous Melanoma pM1 TNM Finding v7

description: Cutaneous melanoma with detectable evidence of distant metastases. (from AJCC 7th Ed.)


name: Grade 4 Extraocular Muscle Paresis, CTCAE

description: Bilateral paresis requiring head turning to see beyond central 60 degrees or double vision in central gaze


Grade 1 Vasculitis, CTCAE

description: Asymptomatic, intervention not indicated


Enterocolitis, CTCAE

description: A disorder characterized by inflammation of the small and large intestines.


name: Grade 2 Neonatal Pulmonary Hemorrhage, AE

description: An adverse event in a newborn characterized by hemorrhagic secretion in an endotracheal (ET) tube; without relevant increase in partial pressure of carbon dioxide (pCO2) or decrease in oxygenation; requiring minor changes in care (e.g. increase in positive end-expiration pressure (PEEP)).


name: Ampulla of Vater Neuroendocrine Tumor G2

description: A well differentiated, intermediate grade neoplasm with neuroendocrine differentiation that arises from the ampulla of Vater and the periampullary region. The mitotic count is 2-20 per 10 HPF.


Advanced Lymphoma

description: Lymphoma that has spread extensively to other anatomic sites or is no longer responding to treatment.


name: Grade 5 Non-Infectious Wound Complication, CTCAE


Stage IIC Appendix Carcinoma AJCC v7

description: Stage IIC includes: T4b, N0, M0. T4b: Tumor directly invades other organs or structures.  N0: No regional lymph node metastasis.  M0: No distant metastasis. (AJCC 7th ed.)


Grade 4 Otitis Media, CTCAE

description: Life-threatening consequences; urgent intervention indicated


name: Chest Pain Along Left Anterior Axillary Line

description: The location of the chest pain is along the anterior axillary line on the left side.


6/8 HLA Match

description: Degree of HLA match is 6/8 alleles with fewer than 2 mismatches per locus at HLA-A, -B, -C and -DRB1.


Cervical Cancer by AJCC v9 Stage

description: A term that refers to the staging of cervical cancer according to the American Joint Committee on Cancer, 9th edition. This staging system applies to carcinomas and carcinosarcomas. It does not apply to sarcomas, lymphomas, and melanomas. Sarcomas are staged according to the corpus uteri classification for sarcomas. Lymphomas are staged according to Hodgkin and non-Hodgkin lymphoma classification. Melanomas are not staged. (from AJCC 9th Ed.)


name: Non-Rheumatic Pulmonary Valve Stenosis with Insufficiency

description: Evidence of non-rheumatic pulmonary valve stenosis with insufficiency.


name: Nasal Cavity and Paranasal Sinuses Cancer cN3b TNM Finding v8

description: Nasal cavity and paranasal sinuses cancer with metastasis in any node(s) with clinically overt ENE(+) (ENEc). (from AJCC 8th Ed.)


Grade 2 Hiccups, CTCAE

description: Moderate symptoms; medical intervention indicated; limiting instrumental ADL


name: Hemiplegia following Other Non-Traumatic Intracranial Hemorrhage Affecting Unspecified Side

description: Evidence of hemiplegia following other non-traumatic intracranial hemorrhage affecting unspecified side.


bite injury

description: A wound inflicted by the teeth or fangs of an individual or animal.


name: Type 2 Diabetes Mellitus with Moderate Nonproliferative Diabetic Retinopathy without Macular Edema, Left Eye

description: Evidence of type 2 diabetes mellitus with moderate nonproliferative diabetic retinopathy without macular edema in the left eye.


name: Blood and Lymphatic System Disorders, CTCAE


name: Merkel Cell Carcinoma pN1 TNM Finding v8

description: Merkel cell carcinoma with metastasis in regional lymph node(s). (from AJCC 8th Ed.)


Childhood Schwannoma

description: A schwannoma that occurs during childhood.


name: Major Salivary Gland Cancer TNM Finding v7

description: A finding about one or more characteristics of major salivary gland cancer, following the rules of the TNM AJCC v7 classification system.  This classification applies to parotid, submandibular, and sublingual glands. (from AJCC 7th Ed.)


Recurring Adverse Event

description: An adverse event that occurs and resolves during a cycle or course of medical intervention and then reoccurs in a later cycle or course.


name: Digestive System Neuroendocrine Tumor by AJCC v7 Stage

description: A term that refers to the staging of a digestive system neuroendocrine tumor, following the rules of the TNM AJCC v7 classification system.


Grade 1 Eyelid Function Disorder, CTCAE

description: Asymptomatic; clinical or diagnostic observations only; intervention not indicated


Methemoglobinemia, CTCAE

description: A disorder characterized by laboratory test results that indicate increased methemoglobin in the blood.


name: Childhood Hodgkin Lymphoma by Toronto Guidelines v2 Stage

description: A term that refers to the staging of childhood Hodgkin lymphoma according to the Toronto childhood cancer staging guidelines v2. Staging is the same for both tiers (tier 1 and 2).


Rectal Pain

description: Pain in the rectal area.


Retinoblastoma cN2 TNM Finding v7

description: Retinoblastoma with distal lymph node involvement. (from AJCC 7th Ed.)


name: Grade 2 Nervous System Disorders - Other, Specify, CTCAE

description: Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL


name: Monoplegia, Unspecified Affecting Left Dominant Side

description: Evidence of monoplegia, unspecified affecting left dominant side.


name: Grade 2 Spinal Cord Intra-Operative Injury, CTCAE


Stage IIA1 Cervical Cancer AJCC v8

description: Stage IIA1 includes: T2a1, Any N, M0. T2a1: Cervical carcinoma invading beyond the uterus but not to the pelvic wall or to lower third of vagina without parametrial invasion. Clinically visible lesion 4.0 cm or less in greatest dimension. M0: No distant metastasis. (AJCC 8th Ed.)


name: Anemia Complicating Pregnancy, First Trimester

description: Evidence of anemia complicating pregnancy in the first trimester.


name: Type 1 Diabetes Mellitus with Severe Nonproliferative Diabetic Retinopathy without Macular Edema

description: Evidence of type 1 diabetes mellitus with severe nonproliferative diabetic retinopathy without macular edema.


Refractory Neuroendocrine Carcinoma

description: Neuroendocrine carcinoma that does not respond to treatment.


Adenosarcoma pT3 TNM Finding v7

description: Tumor involves abdominal tissues. (from AJCC 7th Ed.)


Cutaneous Melanoma by AJCC v8 Stage

description: A term that refers to the staging of cutaneous melanoma, following the rules of the TNM AJCC v8 classification system. This staging system does not apply to melanoma of the conjunctiva, melanoma of the uvea, mucosal melanoma arising in the head and neck, and mucosal melanoma of the urethra, vagina, rectum, and anus. (from AJCC 8th Ed.)


name: Pelvis Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils NOS, CTCAE


name: Malignant neoplasm of bones of skull and face

description: Evidence of a malignant neoplasm of the bones of skull and face.


name: Grade 2 Small Intestinal Perforation, CTCAE

description: Invasive intervention not indicated


Dermal nerve sheath myxoma

description: A usually painless, slow growing benign tumor that most often arises from the extremities. It is characterized by the presence of abundant myxoid matrix and small epithelioid neoplastic Schwann cells.


Congenital Amegakaryocytosis

description: A rare disorder of infancy characterized by marked reduction or absence of megakaryocytes and thrombocytopenia.


Thyroid Cancer pT1a TNM Finding v7

description: Thyroid cancer with a tumor size of 1 cm or less in greatest dimension, limited to the thyroid gland. (from AJCC 7th Ed.)


name: Grade 2 Thyroid Intra-Operative Injury, CTCAE


name: Grade 2 Stoma GI Stricture or Stenosis, CTCAE


Grade 1 Duodenal Fistula, CTCAE

description: Asymptomatic


name: Maxillary Sinus Cancer pN3 TNM Finding v6 and v7

description: Maxillary sinus cancer with metastasis in a lymph node, more than 6 cm in greatest dimension. (from AJCC 6th and 7th Eds.)


name: Diffuse Follicular Center Lymphoma, Lymph Nodes of Multiple Sites

description: Evidence of diffuse follicular center lymphoma, lymph nodes of multiple sites.


Ventricular Fibrillation, CTCAE 5.0

description: A disorder characterized by a dysrhythmia without discernible QRS complexes due to rapid repetitive excitation of myocardial fibers without coordinated contraction of the ventricles.


Gastroesophageal Junction Carcinoma

description: A carcinoma that arises from the gastroesophageal junction. The vast majority of cases are adenocarcinomas. Rare cases are neuroendocrine carcinomas.


Clinical TNM Finding

description: TNM staging performed with access to clinical information only.


name: Monoplegia of Upper Limb following Other Cerebrovascular Disease Affecting Left Non-Dominant Side

description: Evidence of monoplegia of upper limb following other cerebrovascular disease affecting left non-dominant side.


name: Malignant Neoplasm of Unspecified Site of Left Eye

description: Evidence of a malignant neoplasm of an unspecified site of left eye.


Cervical Cancer pTX TNM Finding v8

description: Cervical cancer in which the primary tumor cannot be assessed. (from AJCC 8th Ed.)


Lung Cancer pM1b TNM Finding v7

description: Distant metastasis. (from AJCC 7th Ed.)


name: Nasal Cavity and Paranasal Sinuses Cancer pN3a TNM Finding v8

description: Nasal cavity and paranasal sinuses cancer with metastasis in a lymph node larger than 6 cm in greatest dimension and ENE(-). (from AJCC 8th Ed.)


name: Grade 5 Psychosis Including Hallucinations and Delusions, CTCAE


name: Grade 1 Cranial Nerve VIII Neuropathy, CTCAE


name: Soft Tissue Sarcoma of the Trunk and Extremities Clinical Distant Metastasis TNM Finding v8

description: A clinical finding about one or more characteristics of soft tissue sarcoma of the trunk and extremities, following the rules of the TNM AJCC v8 classification system as they pertain to distant metastases.


Cannabis dependence, episodic

description: Physical and psychological dependence on the drug cannabis, which is associated with a pattern of episodic use.


name: Lymphocyte-Depleted Classic Hodgkin Lymphoma, Intra-abdominal Lymph Nodes

description: Evidence of lymphocyte-depleted classic Hodgkin lymphoma in the intra-abdominal lymph nodes.


name: Overlapping malignant neoplasm of pancreas

description: Evidence of a malignant neoplasm of overlapping sites of the pancreas.


name: Non-Rheumatic Aortic Valve Disorder, Unspecified

description: Evidence of non-rheumatic aortic valve disorder.


Closed dislocation of hip

description: A closed dislocation of the hip.


name: Grade 5 Spleen Infection with Unknown Absolute Neutrophil Count, CTCAE


name: Fallopian Tube Cancer pT1b TNM Finding v7

description: Fallopian tube cancer with tumor limited to both tubes, without penetrating the serosal surface; no ascites. (from AJCC 7th Ed.)


name: Grade 1 Joint Intra-Operative Injury, CTCAE


Grade 4 Lymph Gland Infection, CTCAE

description: Life-threatening consequences; urgent intervention indicated


name: Atherosclerosis of Native Arteries of Left Leg with Ulceration of Ankle

description: Evidence of atherosclerosis of native arteries of left leg with ulceration of ankle.


Cutaneous Melanoma pN3 TNM Finding v8

description: Cutaneous melanoma with four or more tumor-involved nodes or in-transit satellite, and/or microsatellite metastases with two or more tumor-involved nodes, or any number of matted nodes without or with in-transit, satellite, and/or microsatellite metastases. (from AJCC 8th Ed.)


name: Metastatic Pancreatic Neuroendocrine Neoplasm

description: A pancreatic neuroendocrine neoplasm that has spread from its original site of growth to another anatomic site.


Grade 4 Hypocalcemia, CTCAE

description: Corrected serum calcium of <6.0 mg/dL; <1.5 mmol/L; Ionized calcium <0.8 mmol/L; life-threatening consequences


Genetic Predisposition to Neoplasm

description: The predisposition of an individual to develop a neoplasm based on their heredity.


name: Grade 3 Cranial Nerve V Neuropathy, CTCAE


Loss of Stoma

description: The unplanned closing of a stoma.


Grade 3 Dyspnea, CTCAE

description: Shortness of breath at rest; limiting self care ADL


Peripheral Ischemia, CTCAE

description: A disorder characterized by impaired circulation to an extremity.


name: Myelodysplastic Chronic Myelomonocytic Leukemia

description: Chronic myelomonocytic leukemia characterized by the absence of a markedly elevated white blood cell count in the peripheral blood.


name: Choroidal and Ciliary Body Melanoma pT1c TNM Finding v8

description: Choroidal and ciliary body melanoma, tumor size category 1 without ciliary body involvement but with extraocular extension 5 mm or less in largest diameter. (from AJCC 8th Ed.)


Grade 3 Chronic Kidney Disease, CTCAE

description: eGFR or CrCl 29-15 ml/min/1.73 m2


name: Upper Extremity Vein Intra-Operative Injury, CTCAE


Poroid Hidradenoma

description: A poroma characterized by the presence of a single or several nodules of neoplastic cells forming solid and cystic areas in the dermis.


PSA Level Less than or Equal to Five

description: A blood concentration of prostate specific antigen less than or equal to 5 ng/mL.


name: Malnutrition in mother complicating childbirth

description: Evidence of malnutrition in childbirth.


name: Non-Neoplastic Hematologic and Lymphocytic Disorder

description: A non-neoplastic disorder that arises from hematopoietic and lymphoid cells. It is characterized by the absence of a clonal cellular component. It rarely progresses to a malignant neoplasm.


name: Oropharyngeal Cancer Clinical Distant Metastasis TNM Finding v7

description: A clinical finding about one or more characteristics of oropharyngeal cancer, following the rules of the TNM AJCC v7 classification system as they pertain to distant metastases.


name: Duodenum/Ampulla/Jejunum/Ileum Neuroendocrine Tumor pT2 TNM Finding v7

description: Duodenum/ampulla/jejunum/ileum neuroendocrine tumor invading muscularis propria or is more than 1 cm in size (small intestinal tumors); for ampullary tumors: tumor more than 1 cm. (from AJCC 7th Ed.)


Grade 3 Hypoparathyroidism, CTCAE

description: Severe symptoms; medical intervention or hospitalization indicated


name: Grade 5 Treatment Related Secondary Malignancy, CTCAE

description: Death


Stage II Urethral Cancer AJCC v8

description: Stage II includes: T2, N0, M0. T2: For male penile urethra and female urethra: Tumor invades any of the following: corpus spongiosum, periurethral muscle. For prostatic urethra: Tumor invades the prostatic stroma surrounding ducts either by direct extension from the urothelial surface or by invasion from prostatic ducts. N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 8th ed.)


name: Grade 1 Supraventricular Arrhythmia NOS, CTCAE


Mesonephric Hyperplasia

description: A hyperplasia of the mesonephric cells.


name: Stage IB Ampulla of Vater Cancer AJCC v7

description: Stage IB includes: T2, N0, M0. T2: Tumor invades the duodenal wall.  N0: No regional lymph node metastasis.  M0: No distant metastasis. (from AJCC 7th Ed.)


name: Gastrointestinal Stromal Tumor Pathologic Regional Lymph Nodes TNM Finding v7

description: A pathologic finding about one or more characteristics of gastrointestinal stromal tumor, following the rules of the TNM AJCC v7 classification system as they pertain to staging of regional lymph nodes.


Corrosive injury

description: Destruction of tissue by a chemical substance.


name: Juvenile Rheumatoid Arthritis with Systemic Onset, Left Hip

description: Evidence of juvenile rheumatoid arthritis with systemic onset in the left hip.


Grade 4 Neonatal Bradyarrhythmia, AE

description: A bradyarrhythmia adverse event in a newborn characterized by life-threatening consequences (e.g. shock); requiring urgent major care changes.


name: Distal Bile Duct Cancer Pathologic Distant Metastasis TNM Finding v8

description: A pathologic finding about one or more characteristics of distal bile duct cancer, following the rules of the TNM AJCC v8 classification system as they pertain to distant metastases.


name: Grade 4 Salivary Gland Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


name: Grade 2 Peristomal Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


Uveal Melanoma pN1b TNM Finding v8

description: Uveal melanoma in which no regional lymph nodes are positive, but there are discrete tumor deposits in the orbit that are not contiguous to the eye. (from AJCC 8th Ed.)


name: Maxillary Sinus Cancer pT3 TNM Finding v6 and v7

description: Maxillary sinus cancer with tumor invading any of the following: bone of the posterior wall of maxillary sinus, subcutaneous tissues, floor or medial wall of orbit, pterygoid fossa, or ethmoid sinuses. (from AJCC 6th and 7th Eds.)


name: Contact lens overwear syndrome (disorder)

description: Ocular pain which may be very intense, accompanied by corneal epithelium damage, conjunctival injection, lacrimation, blepharospasm, photophobia and hazy vision following corneal edema caused by overwear of contact lenses, principally the PMMA type.


Subglottic Cancer pT3 TNM Finding v8

description: Subglottic cancer with tumor limited to the larynx with vocal cord fixation and/or invasion of paraglottic space and/or inner cortex of the thyroid cartilage. (from AJCC 8th Ed.)


name: Exocrine Pancreatic Cancer pT1 TNM Finding v8

description: Exocrine pancreatic cancer with tumor measuring 2 cm or less in greatest dimension. (from AJCC 8th Ed.)


neuroendocrine carcinoma of anal canal

description: An aggressive, high-grade, and poorly differentiated carcinoma with neuroendocrine differentiation that arises from the anal canal. The mitotic count is more than 20 per 10 HPF. It is classified as either small or large cell neuroendocrine carcinoma based on the size of the malignant cells, the prominence of the nucleoli, and the amount of cytoplasm.


name: Grade 3 Restrictive Cardiomyopathy, CTCAE

description: Symptomatic heart failure or other cardiac symptoms, responsive to intervention; new onset of symptoms


PSA Level 0.2 to Ten

description: A blood concentration of prostate specific antigen between 0.2 and 10 ng/mL.


Out of Plane Wrap Around Artifact

description: An artifact that occurs when tissues in another plane get added to the image.


Acral Melanoma

description: A cutaneous melanoma that arises from the palms, soles, and nails.


Breast Cancer pT4 TNM Finding v8

description: Breast cancer with tumor of any size with direct extension to the chest wall and/or to the skin (ulceration or macroscopic nodules); invasion of the dermis alone does not qualify as T4. (from AJCC 8th Ed.)


Supraglottic Cancer pT4a TNM Finding v6

description: Supraglottic cancer with tumor invading through thyroid cartilage and/or invading tissue beyond the larynx (e.g. trachea, soft tissues of neck including deep extrinsic muscle of the tongue, strap muscles, thyroid, or esophagus). (from AJCC 6th Ed.)


Grade 2 Bullous Dermatitis, CTCAE

description: Blisters covering 10-30% BSA; painful blisters; limiting instrumental ADL


name: Lugano Classification Limited Stage Adult Hodgkin Lymphoma AJCC v8

description: Limited stage adult Hodgkin lymphoma based on the Lugano classification criteria. It includes stages I, IE, II, and IIE. (from AJCC 8th Ed.)


Additional Disease-Related Findings

description: A determination of additional abnormalities and/or other observations that may be associated with the disease of interest, for which a targeted test has not been identified in the data.


name: Soft Tissue Sarcoma of the Trunk and Extremities pT4 TNM Finding v8

description: Soft tissue sarcoma of the trunk and extremities with tumor measuring more than 15 cm in greatest dimension. (from AJCC 8th Ed.)


Burning Chest Pain

description: The sensation of chest pain described as an intense discomfort, similar to that experience as a result of a thermal burn, distinct from sharp, stabbing or aching, often related to nerves; sometimes used to describe gastric or esophageal pain.


Unresectable Adenoid Cystic Carcinoma

description: Adenoid cystic carcinoma that is not amenable to surgical resection.


Intraoperative Head and Neck Injury

description: Damage to head and neck during a surgical procedure.


Tumor Cell Seeding

description: The spread of benign or malignant tissue that can occur naturally, during a medical or surgical procedure or mechanically.


Testicular Cancer TNM Finding v7

description: A finding about one or more characteristics of testicular cancer, following the rules of the TNM AJCC v7 classification system.


name: AIDS-Related Diffuse Small Cleaved Cell Lymphoma

description: A non-Hodgkin lymphoma occurring in HIV-positive patients.  It is composed of small cleaved lymphocytes.


Malignant Neoplasm of Left Lower Limb

description: Evidence of a malignant neoplasm of the left lower limb.


name: Sarcoma of the Orbit Pathologic Primary Tumor TNM Finding v7

description: A pathologic finding about one or more characteristics of sarcoma of the orbit, following the rules of the TNM AJCC v7 classification system as they pertain to staging of the primary tumor.


name: Atherosclerosis of Native Arteries of the Extremities with Gangrene, Bilateral Legs

description: Evidence of atherosclerosis of native arteries of the extremities with gangrene in both legs.


Grade 3 Hypertriglyceridemia, CTCAE

description: >500 mg/dL-1000 mg/dL; >5.7 mmol/L-11.4 mmol/L


name: Bile Duct Mucinous Cystic Neoplasm, Low Grade

description: A non-invasive mucinous cystic neoplasm that arises from the intrahepatic or extrahepatic bile ducts.  It is characterized by the presence of mild atypia.


Childhood Gliosarcoma

description: A gliosarcoma that occurs during childhood.


name: rheumatoid heart disease with rheumatoid arthritis of hip

description: Evidence of rheumatoid heart disease with rheumatoid arthritis of unspecified hip.


Grade 1 Radiculitis, CTCAE

description: Mild symptoms


Grade 5 Hepatic Hemorrhage, CTCAE

description: Death


name: Undifferentiated Carcinoma of Unknown Primary

description: An undifferentiated carcinoma which has metastasized to another anatomic site and the original site of growth has not been identified.


Grade 4 Wheezing, CTCAE

description: Life-threatening consequences; urgent intervention indicated


name: Uterine Corpus Leiomyosarcoma and Endometrial Stromal Sarcoma pT2a TNM Finding v8

description: Uterine corpus leiomyosarcoma or endometrial stromal sarcoma with tumor extending beyond the uterus, within the pelvis and involving adnexa. (from AJCC 8th Ed.)


Uveal Melanoma pM1b TNM Finding v8

description: Uveal melanoma with largest diameter of the largest metastasis 3.1-8.0 cm. (from AJCC 8th Ed.)


name: Grade 5 Brain Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


Parapsoriasis lichenoides

description: A rare condition that stimulated chronic radiodermatitis.  It is considered a variant of mycosis fungoides.


name: acute undifferentiated leukemia in relapse

description: The reemergence of acute undifferentiated leukemia after a period of remission.


name: Diabetes Mellitus due to Underlying Condition with Proliferative Diabetic Retinopathy with Macular Edema

description: Evidence of diabetes mellitus due to underlying condition with proliferative diabetic retinopathy with macular edema.


Sweat Gland Tubular Carcinoma

description: An aggressive adenocarcinoma that arises from the sweat glands. It usually presents as a firm, erythematous nodular lesion in the axilla. Morphologically, it is characterized by the presence of tubular structures and apocrine differentiation.


Stage III Vulvar Cancer AJCC v8

description: Stage III includes: T1-T2, N1-N2c, M0. T1: Tumor confined to the vulva and/or perineum. Multifocal lesions should be designated as such. The largest lesion or the lesion with the greatest depth of invasion will be the target lesion identified to address the highest pT stage. Depth of invasion is defined as the measurement of the tumor from the epithelial-stromal junction of the adjacent most superficial dermal papilla to the deepest point of invasion. T2: Tumor of any size with extension to adjacent perineal structures (lower/distal third of the urethra, lower/distal third of the vagina, anal involvement). N1: Regional lymph node metastasis with one or two lymph node metastases each less than 5 mm, or one lymph node metastasis equal to 5 mm. N2a: Three or more lymph node metastases each less than 5 mm. It includes micrometastasis, N2mi. N2b: Two or more lymph node metastases equal to 5 mm. N2c: Lymph node(s) metastasis with extranodal extension. M0: No distant metastasis. (AJCC 8th Ed.)


name: Atherosclerosis of Unspecified Type of Bypass Graft(s) of the Right Leg with Ulceration of Thigh

description: Evidence of atherosclerosis of unspecified type of bypass graft(s) of the right leg with ulceration of thigh.


name: Reaction to Medicinal Component of Device

description: Any local or systemic adverse reaction to the medicinal component of a combination product.


name: Rheumatoid Lung Disease with Rheumatoid Arthritis of Right Wrist

description: Evidence of rheumatoid lung disease with rheumatoid arthritis of right wrist.


Parathyroid chief-cell hyperplasia

description: A hyperplasia of the chief cells of the parathyroid gland.


Colorectal Cancer cM0 TNM Finding v7

description: Colorectal cancer without evidence of distant metastasis. (from AJCC 7th Ed.)


name: Joints and Fascia Complete Response GvHD

description: Both an NIH joint and fascia score of 0 and a P-ROM score of 25 after previous GvHD involvement by at least 1 measure.


name: Recurrent Platinum-Sensitive Endometrial Carcinoma

description: The reemergence of platinum-sensitive endometrial carcinoma after a period of remission.


name: Grade 3 Vagina Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


name: Grade 5 Artery Infection with Unknown Absolute Neutrophil Count, CTCAE


Lower Thigh Pain

description: A painful sensation in the distal thigh area.


name: Non-Follicular Diffuse Lymphoma, Unspecified, Intra-abdominal Lymph Nodes

description: Evidence of unspecified non-follicular diffuse lymphoma in the intra-abdominal lymph nodes.


name: Major Salivary Gland Cancer pN1 TNM Finding v8

description: Major salivary gland cancer with metastasis in a single ipsilateral lymph node, 3 cm or less in greatest dimension and ENE(-). (from AJCC 8th Ed.)


name: Melanoma in Situ of Unspecified Upper Limb, Including Shoulder

description: Evidence of melanoma in situ of unspecified upper limb including the shoulder.


name: Chronic Active Hepatitis NEC in NCI Thesaurus

description: Evidence of chronic active hepatitis, not elsewhere classified.


name: Grade 3 Esophageal Anastomotic Leak, CTCAE

description: Severe symptoms; invasive intervention indicated


Grade 2 Vaginal Discharge, CTCAE

description: Moderate to heavy vaginal discharge; use of perineal pad or tampon indicated


name: PSA Level Greater than or Equal to Forty

description: A blood concentration of prostate specific antigen greater than or equal to 40 ng/mL.


Balloon cell nevus

description: An uncommon variant of melanocytic nevus. It presents as a small pigmented skin lesion. It is characterized by the presence of large melanocytes with clear, foamy or finely vacuolated cytoplasm. It may recur if it is not completely excised.


Endocrine Therapy Toxicity

description: Indicates that a toxicity adverse effect has been experienced during endocrine drug treatment.


Microcyst

description: A tiny cyst that is usually identified by microscopic examination in a tissue specimen.


Other specified leukemias, in remission

description: Evidence of other specified leukemias, in remission not specified elsewhere.


Iodine Uptake Alteration

description: A finding indicating a deficiency or excess in biological absorption or assimilation of iodine.


Sacral Myelocele

description: Herniation of spinal cord tissue and meninges through a defect in the sacral region of the vertebral column. The protrusion of the tissue is flush with the level of the skin surface.


Grade 2 Neonatal Sinus Bradycardia, AE

description: An adverse event in a newborn characterized by persistent sinus bradycardia; no change in age-appropriate behavior; requiring minor care changes (e.g. concomitant medication adapted, intermittent increase of fraction of inspired oxygen (FiO2)).


BCR/ABL1 Fusion Negative

description: Indicates that expression of the BCR/ABL1 fusion has not been detected in a sample.


Gallbladder Perforation, CTCAE 5.0

description: A disorder characterized by a rupture in the gallbladder wall.


name: Grade 4 Pancreatic Anastomotic Leak, CTCAE

description: Life-threatening consequences; urgent operative intervention indicated


Grade 5 Hepatic Infection, CTCAE

description: Death


name: Grade 3 Wound Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


Grade 5 Anorectal Infection, CTCAE

description: Death


Metastatic Neoplasm to the Bladder

description: The spread of a malignant neoplasm to the urinary bladder wall from an adjacent or distant anatomic site.


name: Gallbladder Cancer Pathologic Primary Tumor TNM Finding v6

description: A pathologic finding about one or more characteristics of gallbladder cancer, following the rules of the TNM AJCC v6 classification system as they pertain to staging of the primary tumor.


Grade 5 Tracheal Hemorrhage, CTCAE

description: Death


name: Stage y-III Childhood Malignant Kidney Neoplasm Excluding Renal Cell Carcinoma by Toronto Guidelines v2, International Society of Pediatric Oncology (SIOP) Protocol

description: Incomplete excision of the tumor (gross or microscopic extension beyond the resection margins). Involved abdominal lymph nodes, including necrotic tumor or chemotherapy-induced changes. Tumor rupture before or intraoperatively. Tumor has penetrated the peritoneal surface. Tumor thrombi present at resection margins. Surgical biopsy prior to resection (does not include needle biopsy). (Childhood cancer staging for population registries according to the Toronto Childhood Cancer Stage Guidelines - Version 2. Cancer Council Queensland and Cancer Australia: Brisbane, Australia; 2021.)


Grade 3 Hypomagnesemia, CTCAE

description: <0.9-0.7 mg/dL; <0.4-0.3 mmol/L


Spinal enthesopathy of thoracic region

description: Evidence of spinal enthesopathy in the thoracic region.


name: Long-Term Effects Secondary to Cancer Therapy in Children


name: Lugano Classification Stage III Adult Lymphoma AJCC v8

description: Stage III: Involvement of lymph node regions on both sides of the diaphragm; nodes above the diaphragm with spleen involvement. (from AJCC 8th Ed.)


name: Appendiceal Carcinoma cM1 TNM Finding v7

description: Appendiceal carcinoma with distant metastasis. (from AJCC 7th Ed.)


Prolapse of Urostomy, CTCAE

description: A finding of displacement of the urostomy.


Acute Submassive Pulmonary Embolism

description: Acute pulmonary embolism with evidence of right ventricular dysfunction, but not associated with systemic hypotension.


Cutaneous Melanoma cN2c TNM Finding v7

description: Cutaneous melanoma with intralymphatic metastases (in transit or satellite metastases) without metastatic nodes. (from AJCC 7th Ed.)


name: Enterochromaffin-Like Cell Neuroendocrine Tumor G1

description: A well differentiated, low grade neuroendocrine neoplasm (carcinoid tumor) arising from the gastrointestinal tract. It is characterized by the presence of enterochromaffin-like type granules in the neoplastic cells.


Normal Appearance of Extremities

description: An indication that the extremities demonstrate no anomalies on visual inspection.


Colonic Fistula, CTCAE

description: A disorder characterized by an abnormal communication between the large intestine and another organ or anatomic site.


name: Exocrine Pancreatic Cancer pT1a TNM Finding v8

description: Exocrine pancreatic cancer with tumor measuring 0.5 cm or less in greatest dimension. (from AJCC 8th Ed.)


name: Invasive Conventional Urothelial Carcinoma

description: Invasive urothelial carcinoma characterized by the presence of malignant cells forming trabeculae, cords, sheets, and nests. Individual malignant cells are also present.


Urethral Cancer pT1 TNM Finding v7

description: Urethral cancer with tumor invading subepithelial connective tissue. (from AJCC 7th Ed.)


name: Grade 4 Small Bowel Perforation NOS, CTCAE


name: Perihilar Bile Duct Cancer pT0 TNM Finding v8

description: Perihilar bile duct cancer with no evidence of primary tumor. (from AJCC 8th Ed.)


Stage IVB Gallbladder Cancer AJCC v7

description: Stage IVB includes: (Any T, N2, M0); (Any T, Any N, M1).  N2: Metastases to periaortic, pericaval, superior mesenteric artery, and/or celiac artery lymph nodes.  M0: No distant metastasis.  M1: Distant metastasis. (from AJCC 7th Ed.)


PSA Level Greater than One Hundred

description: A blood concentration of prostate specific antigen greater than 100 ng/mL.


name: Clinical Stage I Gastroesophageal Junction Adenocarcinoma AJCC v8

description: Stage I includes: T1, N0, M0. T1: Tumor invades the lamina propria, muscularis mucosae, or submucosa. N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 8th ed.)


Hallucinogen abuse, in remission

description: Evidence of hallucinogen abuse, in remission.


name: Other specified types of non-Hodgkin lymphoma, spleen

description: Evidence of other specified types of non-Hodgkin lymphoma in the spleen not specified elsewhere.


name: Melanoma of the Uvea cM1a TNM Finding v7

description: Melanoma of the uvea with distant metastasis, with the largest diameter of the largest metastasis measuring 3 cm or less. (from AJCC 7th Ed.)


name: Metastatic Malignant Neoplasm in the Female Reproductive System

description: The spread of a malignant neoplasm to the female reproductive system from an adjacent or distant anatomic site.


name: Retinoblastoma Pathologic TNM Finding v7

description: A pathologic finding about one or more characteristics of retinoblastoma, following the rules of the TNM AJCC v7 classification system.


name: IgM Monoclonal Gammopathy of Undetermined Significance, Not Otherwise Specified

description: A subtype of IgM monoclonal gammopathy of undetermined significance that includes cases associated with MYD88 mutation and cases associated with the presence of monoclonal B-lymphocytes without the presence of abnormal lymphoplasmacytic aggregates that are diagnostic of lymphoplasmacytic lymphoma or other small B-lymphocytic neoplasms.


Pseudoresponse

description: A marked decrease in contrast enhancement that is not due to actual tumor shrinkage, but that may be due to anti-angiogenic therapy or an increase in steroid dosage.


name: Other Stimulant Dependence with Intoxication, Unspecified

description: Evidence of other stimulant dependence with intoxication not specified elsewhere.


name: Grade 5 Fallopian Tube Infection with Unknown Absolute Neutrophil Count, CTCAE


Folliculitis, CTCAE

description: A disorder characterized by inflammation or infection of the hair follicles.


Chronic Total Occlusion Vessel

description: A longstanding, complete blockage of a vessel. (ACC)


name: Fallopian Tube Cancer pTis TNM Finding v7

description: Fallopian tube cancer with a finding of carcinoma in situ (limited to tubal mucosa). (from AJCC 7th Ed.)


name: Grade 2 Oral Cavity or Gum Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


Hematoma of rectus sheath

description: A collection of blood in the rectus sheath due to disruption of the superior or inferior epigastric arteries, which may present following direct trauma to the rectus abdominis muscle or anticoagulation therapy.


name: Malignant Germinative Follicular Epithelium Neoplasm

description: A malignant neoplasm that arises from germinative follicular epithelial cells.


name: Ampulla of Vater Cancer by AJCC v7 Stage

description: A term that refers to the staging of ampulla of Vater cancer according to the American Joint Committee on Cancer, 7th edition.


name: Recurrent Childhood Central Nervous System Neoplasm

description: The reemergence of central nervous system neoplasm in childhood after a period of remission.


Grade 4 Conduction Disorder, CTCAE

description: Life-threatening consequences


name: Genetic Predisposition to Myofibromatosis

description: An inherited condition caused by mutation(s) in the NOTCH3 or PDGFRB genes, encoding neurogenic locus notch homolog protein 3 and platelet-derived growth factor receptor beta, respectively. The condition is characterized by an increased risk of developing myofibroma.


name: Lip and Oral Cavity Cancer pT3 TNM Finding v8

description: Lip and oral cavity cancer with tumor size greater than 4 cm or any tumor greater than 10 mm DOI. (from AJCC 8th Ed.)


name: Malignant Melanoma of Right Lower Limb, Including Hip

description: Evidence of a malignant melanoma of the right lower limb including the hip.


Recreational Fire Smoke Exposure

description: Environmental, occupational or consumer-based exposure to airborne gases and particulates produced when materials (usually wood) are burned for recreational purposes.


name: Grade 2 Upper Extremity Artery Intra-Operative Injury, CTCAE


Colorectal Cancer pT4a TNM Finding v7

description: Colorectal cancer with penetration to the surface of the visceral peritoneum. (from AJCC 7th Ed.)


Grade 4 Anal Necrosis, CTCAE

description: Life-threatening consequences; urgent operative intervention indicated


name: Grade 1 Cranial Nerve VII Neuropathy, CTCAE


name: Fallopian Tube Cancer cM1 TNM Finding v7

description: Fallopian tube cancer with distant metastasis (excluding metastasis within the peritoneal cavity). (from AJCC 7th Ed.)


Other depressive episodes

description: Evidence of other depressive episodes not specified elsewhere.


Hypothyroidism, CTCAE

description: A disorder characterized by a decrease in production of thyroid hormone by the thyroid gland.


Spiculated or Serrated Nodule

description: A nodule having either spiculated or serrated margin characteristics.


Grade 3 Stroke, CTCAE

description: Severe neurologic deficit; limiting self care ADL; hospitalization


Reiter's Disease, Left Elbow

description: Evidence of Reiter's disease in the left elbow.


Iris Melanoma pT1c TNM Finding v8

description: Iris melanoma with tumor limited to the iris with secondary glaucoma. (from AJCC 8th Ed.)


name: Grade 2 Pleura Infection with Unknown Absolute Neutrophil Count, CTCAE


COVID-19-Associated Stroke

description: Cerebrovascular accident caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).


Receptor Overall Status

description: A qualitative assessment of the status of a biological specimen with regards to a cellular receptor.


Stage 0 Uterine Corpus Cancer

description: Stage 0 includes: Tis, N0, M0. Tis: Carcinoma in situ. N0: No regional lymph node metastasis. M0: No distant metastasis.  This staging applies to carcinomas and carcinosarcomas.  FIGO no longer includes Stage 0 (Tis). (AJCC 7th ed.)


name: Grade 4 Bronchus Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


Grade 3 Pulmonary Edema, CTCAE

description: Severe dyspnea or dyspnea at rest; oxygen indicated; limiting self care ADL


name: Anaplastic Large Cell Lymphoma, ALK-Positive, Lymph Nodes of Axilla and Upper Limb

description: Evidence of anaplastic large cell lymphoma that is ALK-Positive in the lymph nodes of axilla and upper limb.


name: Metastatic Digestive System Neuroendocrine Tumor G2

description: Digestive system neuroendocrine tumor G2 that has spread from its original site of growth to another anatomic site.


name: Gastrointestinal Stromal Tumor pM1 TNM Finding v7

description: Gastrointestinal stromal tumor with distant metastasis. (from AJCC 7th Ed.)


name: Other Psychoactive Substance Dependence with Psychoactive Substance-Induced Sleep Disorder

description: Evidence of other psychoactive substance dependence with psychoactive substance-induced sleep disorder not specified elsewhere.


Gastric Cancer pT3 TNM Finding v7

description: Gastric cancer with tumor penetrating subserosal connective tissue without invasion of visceral peritoneum or adjacent structures.  The adjacent structures of the stomach include the spleen, transverse colon, liver, diaphragm, pancreas, abdominal wall, adrenal gland, kidney, small intestine, and retroperitoneum.  Intramural extension to the duodenum or esophagus is classified by the depth of the greatest invasion in any of these sites, including the stomach. (from AJCC 7th Ed.)


Grade 4 Laryngeal Obstruction, CTCAE

description: Life-threatening consequences; urgent intervention indicated


No Response

description: No apparent change or worsening in lesion staging classification.


Grade 1 Hirsutism, CTCAE

description: In women, increase in length, thickness or density of hair in a male distribution that the patient is able to camouflage by periodic shaving, bleaching, or removal of hair


name: Grade 3 Dental and Teeth and Peridontal Pain, CTCAE


Stage IVB Cervical Cancer FIGO 2018

description: The cervical carcinoma has spread to distant organs. (FIGO 2018)


name: Grade 1 Brain Intra-Operative Injury, CTCAE


name: Atherosclerosis of Non-Autologous Biological Bypass Graft(s) of the Right Leg with Ulceration of Ankle

description: Evidence of atherosclerosis of non-autologous biological bypass graft(s) of the right leg with ulceration of ankle.


name: Cervical Papillary Squamous Cell Carcinoma

description: A human papillomavirus-related cervical squamous cell carcinoma characterized by the presence of papillary structures covered with epithelial cells which show features of cervical intraepithelial neoplasia. The malignant cellular component below the papillary structures is a squamous cell carcinoma.


name: FGFR1/Chromosome 8 Copy Number Ratio Finding

description: A genetic copy number finding indicating the ratio of the number of signals for a probe targeting the FGFR1 gene to the number of signals for a probe targeting chromosome 8.


name: Type 1 diabetes mellitus with diabetic cataract

description: Evidence of type 1 diabetes mellitus with diabetic cataract.


name: Small Intestine Cancer pTis TNM Finding v7

description: Small intestine cancer with a finding of carcinoma in situ. (from AJCC 7th Ed.)


name: Childhood Undifferentiated High Grade Pleomorphic Sarcoma of Bone

description: An undifferentiated high grade pleomorphic sarcoma that arises from the bone and occurs during childhood.


name: Grade 4 Joint Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


Cutaneous Melanoma cN2c TNM Finding v8

description: Cutaneous melanoma with one clinically detected metastasis. Presence of in-transit, satellite, and/or microsatellite metastases: Yes. (from AJCC 8th Ed.)


Refractory Primary Amyloidosis

description: Primary amyloidosis that does not respond to treatment.


name: Hypopharyngeal Cancer Pathologic Regional Lymph Nodes TNM Finding v8

description: A pathologic finding about one or more characteristics of hypopharyngeal cancer, following the rules of the TNM AJCC v8 classification system as they pertain to staging of regional lymph nodes.


name: Conjunctiva Intra-Operative Injury, CTCAE


name: Grade 5 Other Dermatology or Skin, CTCAE


name: Cerebral Infarction due to Unspecified Occlusion or Stenosis of Left Vertebral Artery

description: Evidence of cerebral infarction due to an unspecified occlusion or stenosis of the left vertebral artery.


Plasma Kallikrein Deficiency

description: A coagulation disorder characterized by the partial or complete absence of plasma-type kallikrein activity in the blood.


name: Subacute combined degeneration of spinal cord in diseases classified elsewhere

description: Evidence of subacute combined degeneration of spinal cord in disease classified elsewhere.


name: Other Disease of Blood and Blood-Forming Organs and Certain Disorders Involving the Immune Mechanism Complicating Pregnancy, Second Trimester

description: Evidence of other disease of blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy in the second trimester not specified elsewhere.


name: Unspecified Juvenile Rheumatoid Arthritis, Right Elbow

description: Evidence of unspecified juvenile rheumatoid arthritis in the right elbow.


name: Chronic Post-Rheumatic Arthropathy, Unspecified Hand

description: Evidence of chronic post-rheumatic arthropathy in an unspecified hand.


name: Grade 2 Pregnancy, Puerperium and Perinatal Conditions - Other, Specify, CTCAE

description: Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL


Nipple Deformity, CTCAE

description: A disorder characterized by a malformation of the nipple.


Multifocal Lesion

description: A lesion arising from or having many locations.


name: Uterine Corpus Leiomyosarcoma and Endometrial Stromal Sarcoma pN0 TNM Finding v8

description: Uterine corpus leiomyosarcoma or endometrial stromal sarcoma with no regional lymph node metastasis. (from AJCC 8th Ed.)


Lactation Disorder, CTCAE

description: A disorder characterized by disturbances of milk secretion. It is not necessarily related to pregnancy that is observed in females and can be observed in males.


Grade 5 Ventricular Fibrillation, CTCAE

description: Death


Supraglottic Cancer pN2 TNM Finding v7

description: Supraglottic cancer with metastasis in a single ipsilateral lymph node, more than 3 cm but not more than 6 cm in greatest dimension, or in multiple ipsilateral lymph nodes, none more than 6 cm in greatest dimension, or in bilateral or contralateral lymph nodes, none more than 6 cm in greatest dimension. (from AJCC 7th Ed.)


name: Grade 2 Duodenum Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


name: Childhood Refractory Malignant Solid Neoplasm

description: A childhood malignant solid neoplasm that does not respond to treatment.


name: Esophagus and Esophagogastric Junction Cancer pT1a TNM Finding v8

description: Esophagus and esophagogastric junction cancer with tumor invading the lamina propria or muscularis mucosae. (from AJCC 8th Ed.)


name: Displacement of biological heart valve graft, initial encounter

description: Evidence of displacement of biological heart valve graft, initial encounter.


name: Nasal Cavity and Paranasal Sinuses Cancer cN3a TNM Finding v8

description: Nasal cavity and paranasal sinuses cancer with metastasis in a lymph node larger than 6 cm in greatest dimension and ENE(-). (from AJCC 8th Ed.)


PSA Level Greater than 0.15

description: A blood concentration of prostate specific antigen that is greater than 0.15 ng/mL.


Factor VII Inactivation

description: Presence of inactivating antibodies to factor VII in the blood.


Intraoperative Urinary System Injury

description: Damage to any part of the urinary system during a surgical procedure.


name: Merkel Cell Carcinoma Clinical Primary Tumor TNM Finding v8

description: A clinical finding about one or more characteristics of Merkel cell carcinoma, following the rules of the TNM AJCC v8 classification system as they pertain to staging of the primary tumor.


name: HPV-Mediated (p16-Positive) Oropharyngeal Cancer Clinical Distant Metastasis TNM Finding v8

description: A clinical finding about one or more characteristics of HPV-mediated (p16-positive) oropharyngeal cancer, following the rules of the TNM AJCC v8 classification system as they pertain to distant metastases.


name: Leiomyosarcoma and Endometrial Stromal Sarcoma pT1 TNM Finding v7

description: Tumor limited to the uterus. (from AJCC 7th Ed.)


Blast Injuries

description: The result of physical trauma sustained in an explosion.


Grade 3 Conjunctivitis, CTCAE

description: Symptomatic with marked decrease in visual acuity (best corrected visual acuity worse than 20/40 or more than 3 lines of decreased vision from known baseline, up to 20/200); limiting self care ADL


description: Evidence of cocaine abuse with cocaine-induced psychotic disorder.


Late effects of tuberculosis

description: A pathologic condition that results from Mycobacterium tuberculosis infection.


Grade 2 Urethral Infection, CTCAE

description: Localized; oral intervention indicated (e.g., antibiotic, antifungal, or antiviral)


Discoid Rash

description: A disc-shaped patch(es) of skin inflammation that is red, raised, and scaly; it typically develops on the face, scalp, and neck, and often leaves scars and dyspigmentation as a result of postinflammatory hyperpigmentation.


Grade 4 Perforation Bile Duct, CTCAE

description: Life-threatening consequences; urgent operative intervention indicated


Overlapping malignant neoplasm of vulva

description: Evidence of a malignant neoplasm of overlapping sites of vulva.


Grade 2 Facial Muscle Weakness, CTCAE

description: Moderate symptoms; limiting instrumental ADL


Adult Hodgkin Lymphoma

description: Hodgkin lymphoma occurring in adults.


Signet Ring Cell/Histiocytoid Carcinoma

description: A rare aggressive adnexal carcinoma preferentially affecting the eyelid and histopathologically resembling a metastatic lobular carcinoma of the breast and/or some adenocarcinomas arising in the gastrointestinal tract. (WHO 2018)


name: Type 2 Diabetes Mellitus with Other Skin Complications

description: Evidence of type 2 diabetes mellitus with other skin complications.


name: Post-Immunization Arthropathy, Unspecified Site

description: Evidence of post-immunization arthropathy in an unspecified site.


benign mature teratoma of pancreas

description: A mature teratoma that arises from the pancreas.


name: Recurrent Low Grade Adult Non-Hodgkin's Lymphoma


Early Prosthetic Valve Endocarditis

description: Prosthetic valve endocarditis that occurs days to weeks after surgery.


Immunohistochemical Test Result

description: The result from the immunohistochemical test.


Thyroid Cancer pM0 TNM Finding

description: Thyroid cancer with no evidence of distant metastasis. (from AJCC 6th Ed.)


Advanced Pancreatic Carcinoma

description: Pancreatic carcinoma that has spread extensively to other anatomic sites or is no longer responding to treatment.


Meningohydroencephalocele

description: A congenital neural tube closure defect resulting in protrusion of the brain, the meninges, and the ventricular system through an opening in the skull, usually involving the squamous part of the occipital bone..


Skin squamous cell carcinoma metastatic

description: Squamous cell carcinoma of the skin which has spread to other anatomic sites.


Confusion, CTCAE 5.0

description: A disorder characterized by a lack of clear and orderly thought and behavior.


Grade 2 Cough, CTCAE

description: Moderate symptoms, medical intervention indicated; limiting instrumental ADL


name: Follicular Lymphoma Grade II, Lymph Nodes of Inguinal Region and Lower Limb

description: Evidence of follicular lymphoma grade II in the lymph nodes of inguinal region and lower limb.


name: Grade 4 Cerebral Artery Intra-Operative Injury, CTCAE


Refractory Cervical Adenocarcinoma

description: Cervical adenocarcinoma that is resistant to treatment.


Vaginal Cancer pT1 TNM Finding v8

description: Vaginal cancer with tumor confined to the vagina. (from AJCC 8th Ed.)


name: Grade 1 Cerebrospinal Fluid Leakage, CTCAE

description: Post-craniotomy: asymptomatic; Post-lumbar puncture: transient headache; postural care indicated


name: Lymphatic Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


Chest Pain Along Midclavicular Line

description: The location of the chest pain is along an imaginary vertical line on the chest originating from the midpoint of a clavicle.


Social Setting-related Exposure

description: Exposure to potentially harmful chemical, physical, or biological agents when interacting with other individuals.


High Grade Osteosarcoma

description: An aggressive osteosarcoma with high-grade morphological features. This category includes high-grade surface osteosarcoma and conventional osteosarcoma.


name: Grade 2 Cornea Infection with Unknown Absolute Neutrophil Count, CTCAE


name: Poorly Differentiated Prostate Adenocarcinoma

description: An invasive prostate adenocarcinoma characterized by the presence of poorly differentiated malignant cells.


Breast Cancer TNM Finding v7

description: A finding about one or more characteristics of breast cancer, following the rules of the TNM AJCC v7 classification system.


name: Grade 3 Duodenum Infection with Unknown Absolute Neutrophil Count, CTCAE


name: Cranial Nerve Infection with Unknown Absolute Neutrophil Count, CTCAE


Invasive Nested Urothelial Carcinoma

description: Invasive urothelial carcinoma characterized by a nested growth pattern.


name: Alcohol Use Complicating Pregnancy, Unspecified Trimester

description: Evidence of alcohol use complicating pregnancy in an unspecified trimester.


name: Grade 3 Bronchus Obstruction and Stenosis, CTCAE


Sickle cell-thalassemia disease

description: Hemolytic anemia, in which patients are heterozygous for both the sickle cell gene and a thalassemia gene.


Unfavorable Hodgkin Lymphoma

description: A Hodgkin lymphoma with unfavorable prognosis.


Primary Parathyroid Gland Hyperplasia

description: Parathyroid gland hyperplasia that occurs in the absence of physiological stimuli.


Partial Metabolic Response

description: A decrease of metabolic tumor activity in all relevant lesions, based on a pre-defined threshold.


name: Rheumatoid Arthritis with Rheumatoid Factor of Unspecified Wrist without Organ or Systems Involvement

description: Evidence of rheumatoid arthritis with rheumatoid factor of unspecified wrist without organ or systems involvement.


Stage IVB Osteosarcoma AJCC v7

description: Stage IVB includes: (Any T, N1, Any M, Any G); (Any T, Any N, M1b, Any G).  N1: Regional lymph node metastasis.  M1b: Metastasis to other distant sites. (AJCC 7th ed.)


name: Mantle Cell Lymphoma, Intra-abdominal Lymph Nodes

description: Evidence of mantle cell lymphoma in the intra-abdominal lymph nodes.


name: Grade 2 Muscle Intra-Operative Injury, CTCAE


Infarction of spinal cord

description: Ischemic necrosis of the spinal cord caused by occlusion of the arteries that supply blood to the spinal cord. Signs and symptoms include intermittent back pain, pain in the legs, paralysis, and incontinence.


name: Spinal Cord Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


name: Type 1 Diabetes Mellitus with Stable Proliferative Diabetic Retinopathy, Left Eye

description: Evidence of type 1 diabetes mellitus with stable proliferative diabetic retinopathy in the left eye.


Grade 5 Prostatic Hemorrhage, CTCAE

description: Death


Lower Ribs Pain

description: A sensation of discomfort emanating from the inferiormost (verterbrochondral or vertebral) ribs.


Grade 2 Portal Hypertension, CTCAE

description: Decreased portal vein flow


name: Atherosclerosis of Non-Autologous Biological Bypass Graft(s) of the Extremities with Gangrene, Right Leg

description: Evidence of atherosclerosis of non-autologous biological bypass graft(s) of the extremities with gangrene in the right leg.


name: Other specified diabetes mellitus with diabetic cataract

description: Evidence of other specified diabetes mellitus with diabetic cataract not specified elsewhere.


Skin Granuloma

description: A granuloma located in the skin.


name: Grade 4 Pharynx Mucositis or Stomatitis by Clinical Examination Classification, CTCAE


Cervical Cancer cT2a TNM Finding v7

description: Cervical cancer invades beyond uterus but not to pelvic wall or to lower third of vagina.  There is no parametrial invasion. (from AJCC 7th Ed.)


Uterine Corpus Cancer by AJCC v7 Stage

description: A term that refers to the staging of uterine corpus cancer (carcinoma or carcinosarcoma) according to the American Joint Committee on Cancer, 7th edition.


Grade 1 Penile Infection, CTCAE

description: Localized, local intervention indicated


Injury To Carotid Artery, CTCAE

description: A finding of damage to the carotid artery.


Recurrent Malignant Bone Neoplasm

description: Reemergence of a malignant bone neoplasm after a period of remission.


Failure to Attain Remission

description: Remission status was not attained.


name: Gallbladder Mucinous Cystic Neoplasm with an Associated Invasive Carcinoma

description: A mucinous cystic neoplasm that arises from the gallbladder and it is associated with an invasive carcinomatous component.


name: Sporadic Malignant Peripheral Nerve Sheath Tumor

description: A malignant peripheral nerve sheath tumor that is not caused by inherited genetic mutations.


Carcinoid tumor of the liver

description: An extremely rare, well differentiated neuroendocrine neoplasm arising from the liver. The neoplastic cells express immunohistochemical evidence of neuroendocrine differentiation.


name: Rheumatoid Lung Disease with Rheumatoid Arthritis of Right Shoulder

description: Evidence of rheumatoid lung disease with rheumatoid arthritis of right shoulder.


Grade 2 Glucose Intolerance, CTCAE

description: Symptomatic; dietary modification or oral agent indicated


Voice Alteration

description: Change in the sound and/or speed of the voice. Causes include laryngeal polyp, laryngitis, laryngeal carcinoma, throat carcinoma, Parkinson's disease, multiple sclerosis, stroke, hypothyroidism, oral surgery, tracheostomy, tracheal injury, and laryngeal injury.


Grade 4 Anal Stenosis, CTCAE

description: Life-threatening consequences; urgent operative intervention indicated


PSA Level Greater than or Equal to Ten

description: A blood concentration of prostate specific antigen greater than or equal to 10 ng/mL.


Mediastinal Infection, CTCAE

description: A disorder characterized by an infectious process involving the mediastinum.


Unanticipated Adverse Device Effect

description: Complication occurring in the patient that had not previously been identified or expected for this device.


Grade 3 Sinusitis, CTCAE

description: IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated


Cutaneous Melanoma TNM Finding v8

description: A finding about one or more characteristics of cutaneous melanoma, following the rules of the TNM AJCC v8 classification system. This classification system does not apply to melanoma of the conjunctiva, melanoma of the uvea, mucosal melanoma arising in the head and neck, and mucosal melanoma of the urethra, vagina, rectum, and anus. (from AJCC 8th Ed.)


Grade 1 Malaise, CTCAE

description: Uneasiness or lack of well being


name: TdT Positive Acute Lymphoblastic Leukemia


name: Malignant Neoplasm of Upper-Outer Quadrant of Unspecified Female Breast

description: Evidence of a malignant neoplasm of the upper-outer quadrant of unspecified female breast.


name: Anal Cancer Clinical Distant Metastasis TNM Finding v8

description: A clinical finding about one or more characteristics of anal cancer, following the rules of the TNM AJCC v8 classification system as they pertain to distant metastases.


Anoxia

description: Absence or reduction of oxygen in body tissue.


Adult Gliosarcoma

description: A gliosarcoma occurring in adults.


Adrenal Cancer TNM Finding v7

description: A finding about one or more characteristics of adrenal cancer, following the rules of the TNM AJCC v7 classification system.


name: Duodenum and Ampulla of Vater Neuroendocrine Tumor pT3 TNM Finding v8

description: Duodenum and ampulla of Vater neuroendocrine tumor invading the pancreas or peripancreatic adipose tissue. (from AJCC 8th Ed.)


name: Grade 1 Pancreas Intra-Operative Injury, CTCAE


Stage II Ureter Cancer AJCC v8

description: Stage II includes: T2, N0, M0. T2: Tumor invades the muscularis. N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 8th ed.)


name: Secondary Malignant Neoplasm of Right Kidney and Renal Pelvis

description: Evidence of secondary malignant neoplasm of right kidney and renal pelvis.


Sarcoma of the Orbit pT1 TNM Finding v7

description: Sarcoma of the orbit with tumor measuring 15 mm or less in greatest dimension. (from AJCC 7th Ed.)


name: Ovarian, Fallopian Tube, and Primary Peritoneal Carcinoma Pathologic Distant Metastasis TNM Finding v8

description: A pathologic finding about one or more characteristics of ovarian, fallopian tube, or primary peritoneal carcinoma, following the rules of the TNM AJCC v8 classification system as they pertain to distant metastases.


Reactogenicity

description: An expected set of reactions that may occur soon after injection of a vaccine. These expected adverse reactions are a physical manifestation of the inflammatory response to the vaccine.


name: Ovarian, Fallopian Tube, and Primary Peritoneal Carcinoma pT0 TNM Finding v8

description: Ovarian, fallopian tube, or primary peritoneal carcinoma with no evidence of primary tumor. (from AJCC 8th Ed.)


Mosquito-borne hemorrhagic fever

description: A group of viral illnesses that are vectored by mosquitoes, and that are characterized by increased susceptibility to bleeding diatheses.


Hypomyelinating Leukodystrophy-22

description: An autosomal dominant condition caused by mutation(s) in the CLDN11 gene, encoding claudin-11.  It is characterized by global developmental delay, mild impaired intellectual development, limited ability to walk, and hypomyelinating leukodystrophy on MRI.


name: Grade 2 Artery Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


name: Grade 1 Intraoperative Breast Injury, CTCAE

description: Primary repair of injured organ/structure indicated


name: congenital renal arteriovenous malformation

description: A benign vascular lesion characterized by the presence of a complex network of communicating arterial and venous vascular structures in the kidney.


PSA Level Greater than or Equal to 0.01

description: A blood concentration of prostate specific antigen greater than or equal to 0.01 ng/mL.


name: Grade 2 Cerebrospinal Fluid Leakage, CTCAE

description: Post-craniotomy: moderate symptoms; medical intervention indicated; Post-lumbar puncture: persistent moderate symptoms; blood patch indicated


Grade 5 Neonatal Edema, AE

description: An edema adverse event in a newborn which results in death.


Craniotubular Hyperostosis

description: A group of sclerosing bone dysplasias characterized by pronounced sclerosis of the cranial vault and the long bones, resulting in increased cortical bone density. Most cases are caused by mutation(s) in the SOST or LRP5 genes, encoding sclerostin and low-density lipoprotein receptor-related protein 5, respectively. Other genes have been implicated, and some cases have been described, but do not yet have identified genetic mutations.


name: Hepatic Artery Intra-Operative Injury, CTCAE


Metastatic Bone Disease

description: Metastasis to bone that presents with subjective evidence of disease as perceived by the patient.


name: Monoplegia of Upper Limb following Cerebral Infarction Affecting Unspecified Side

description: Evidence of monoplegia of upper limb following cerebral infarction affecting unspecified side.


description: Evidence of alcohol dependence with alcohol-induced mood disorder.


name: Mantle cell lymphoma of lymph nodes of multiple sites

description: Evidence of mantle cell lymphoma in the lymph nodes of multiple sites.


name: cannabis dependence with intoxication - uncomplicated

description: Evidence of cannabis dependence with intoxication, uncomplicated.


Grade 5 Papulopustular Rash, CTCAE

description: Death


name: Distal Bile Duct Cancer Pathologic TNM Finding v8

description: A pathologic finding about one or more characteristics of distal bile duct cancer, following the rules of the TNM AJCC v8 classification system.


name: Middle Ear Infection with Unknown Absolute Neutrophil Count, CTCAE


name: Grade 2 Cranial Nerve IX Motor Intra-Operative Injury, CTCAE


name: Stage IB Gestational Trophoblastic Tumor AJCC v7

description: Stage IB includes: T1, M0, Risk factors: high risk.  T1: Tumor confined to uterus.  M0: No distant metastasis.  (AJCC 7th ed.)


name: Premature Ventricular Contraction, CTCAE


Dysphagia following Cerebral Infarction

description: Evidence of dysphagia following cerebral infarction.


Pre-treatment Disease Complication

description: A complication of the disease that existed prior to treatment.


Grade 1 Vaginal Fistula, CTCAE

description: Asymptomatic


name: Major Visceral Artery Intra-Operative Injury, CTCAE


Disseminated carcinoma

description: Carcinoma that is spread throughout the body.


Insomnia due to organic factors

description: Insomnia as a result of a physiological cause.


name: Grade 3 Urinary Frequency or Urgency, CTCAE


Nasopharyngeal Cancer pM0 TNM Finding

description: Nasopharyngeal cancer with no distant metastasis. (from AJCC 6th Ed.)


Congenital kyphosis

description: An abnormally increased curvature of the thoracic portion of the spine that is present at the time of birth.


Overlapping Lesion

description: A lesion that extends over the margins of a contiguous lesion.


name: Human Papillomavirus-Related Malignant Neoplasm in AIDS Patient

description: A malignant neoplasm caused by human papillomavirus in an a patient with a history of AIDS.


name: Fallopian Tube Intra-Operative Injury, CTCAE


Hypocalcemia, CTCAE

description: A disorder characterized by laboratory test results that indicate a low concentration of calcium (corrected for albumin) in the blood.


name: Ocular Adnexal Lymphoma pN4 TNM Finding v7

description: Involvement of central lymph nodes. (from AJCC 7th Ed.)


Marrow Complete Response

description: A decrease in the number of bone marrow plasma cells to protocol-defined level(s).


Metastatic Malignant Solid Neoplasm

description: A malignant solid neoplasm that has spread from its original site of growth to another anatomic site.


name: Hemiplegia following Other Cerebrovascular Disease Affecting Right Non-Dominant Side

description: Evidence of hemiplegia following other cerebrovascular disease affecting right non-dominant side.


Grade 3 Scrotal Infection, CTCAE

description: IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated


name: Mediastinal Germ Cell Tumor Primary Tumor TNM Finding

description: A TNM finding about one or more characteristics of a mediastinal germ cell tumor as they pertain to staging of the primary tumor. (WHO Classification of Tumors of the Lung, Pleura, Thymus and Heart, 2015)


Overlapping malignant neoplasm of penis

description: Evidence of a malignant neoplasm of overlapping sites of the penis.


Malignant Neoplasm of Right Ureter

description: Evidence of a malignant neoplasm of the right ureter.


Grade 5 Pneumothorax, CTCAE

description: Death


N1 TNM Finding

description: A general term that refers to a TNM finding of cancer metastases usually in a limited number of regional lymph nodes. The definition of N1 TNM finding depends on the specific type of cancer that it refers to; for example, for breast cancer it refers to micrometastases or metastases in 1-3 axillary lymph nodes; for cutaneous melanoma it refers to metastasis in 1 regional lymph node; for colorectal cancer it refers to metastases in 1-3 regional lymph nodes; and for bladder cancer it refers to metastasis in 1 regional lymph node in the true pelvis.


Tiring Pain

description: A sensation of discomfort or distress that renders an individual weary and without energy.


name: Clinical Stage IVB Gastroesophageal Junction Adenocarcinoma AJCC v8

description: Stage IVB includes: Any T, Any N, M1. M1: Distant metastasis. (AJCC 8th ed.)


name: Reproductive System and Breast Disorders, CTCAE


name: Alkylating Agent-Related Acute Myeloid Leukemia

description: Acute myeloid leukemia occurring as late complication of prior therapy with alkylating agents.


name: Invasive Bladder Large Nested Urothelial Carcinoma

description: A rare invasive bladder urothelial carcinoma characterized the presence of medium to large nests of malignant cells.


name: Complication of labor and delivery, unspecified

description: The occurrence of a pregnancy complication during childbirth, which includes both labor (the process of childbirth) and delivery (the birth itself).


name: Unspecified Atherosclerosis of Non-Biological Bypass Graft(s) of the Extremities, Left Leg

description: Evidence of unspecified atherosclerosis of non-biological bypass graft(s) of the extremities in the left leg.


Fibromyxolipoma

description: A benign well-circumscribed tumor composed of mature adipocytes, characterized by areas of abundant fibrous tissue and extensive myxoid change.


Salt-Wasting 21-Hydroxylase Deficiency

description: A classic form of congenital adrenal hyperplasia characterized by complete absence of 21-hydroxylase activity resulting in deficiency of glucocorticoids and mineralocorticoids accompanied by androgen excess causing virilization in female infants. Mineralocorticoid deficiency results in renal salt-wasting, and if untreated, hyponatremia, hyperkalemia, and shock.


name: Grade 2 Cranial Nerve Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


Appendix Mucinous Cystadenoma

description: A cystically dilated epithelial neoplasm arising from the appendix.  It is characterized by the presence of a cystic structure that is filled with mucus.


name: Systemic involvement of connective tissue, unspecified

description: Evidence of systemic involvement of connective tissue.


name: Gestational Diabetes Mellitus in Puerperium, Controlled by Oral Hypoglycemic Drugs

description: Evidence of gestational diabetes mellitus in puerperium that is controlled by oral hypoglycemic drugs.


name: Hodgkin's disease, nodular sclerosis of lymph nodes of multiple sites

description: Ann Arbor Classification: Stage III: Involvement of lymph node regions on both sides of the diaphragm (III), which also may be accompanied by extralymphatic extension in association with adjacent lymph node involvement (IIIE) or by involvement of the spleen (IIIS) or both (IIIE,S).


Grade 3 Gastroparesis, CTCAE

description: Weight loss >=20% from baseline; tube feeding or TPN indicated; elective operative intervention indicated


name: Metastatic Bladder Small Cell Neuroendocrine Carcinoma

description: Bladder small cell neuroendocrine carcinoma that has spread to another anatomic site.


name: Atherosclerosis of Autologous Vein Bypass Graft(s) of the Extremities with Rest Pain, Right Leg

description: Evidence of atherosclerosis of autologous vein bypass graft(s) of the extremities with rest pain in the right leg.


Bone Response

description: An assessment of the bone response of a disease to a therapy.


name: Prostate Cancer by Whitmore-Jewett Stage

description: A term that refers to the staging of prostate carcinoma according to the Whitmore-Jewett staging system.


Cutaneous Melanoma cN0 TNM Finding v8

description: Cutaneous melanoma without regional lymph node metastasis. Presence of in-transit, satellite, and/or microsatellite metastases: No.  (from AJCC 8th Ed.)


name: Grade 3 Biliary Tree Infection with Unknown Absolute Neutrophil Count, CTCAE


name: Grade 1 Injury To Inferior Vena Cava, CTCAE

description: Asymptomatic diagnostic finding; intervention not indicated


name: Uveal Melanoma Pathologic TNM Finding v8

description: A pathologic finding about one or more characteristics of uveal melanoma, following the rules of the TNM AJCC v8 classification system.


Chylothorax, CTCAE

description: A disorder characterized by milky pleural effusion (abnormal collection of fluid) resulting from accumulation of lymph fluid in the pleural cavity.


name: Small Bowel Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils NOS, CTCAE


name: Clinical Stage II Cutaneous Melanoma AJCC v8

description: Stage II includes: IIA: (T2b, N0, M0); (T3a, N0, M0); IIB: (T3b, N0, M0); (T4a, N0, M0); IIC: (T4b, N0, M0). T2b: Tumor measuring more than 1.0 and equal to or less than 2.0 mm in thickness. Ulceration status: With ulceration. T3a: Tumor measuring more than 2.0 and equal to or less than 4.0 mm in thickness. Ulceration status: Without ulceration. T3b: Tumor measuring more than 2.0 and equal to or less than 4.0 mm in thickness. Ulceration status: With ulceration. T4a: Tumor measuring more than 4.0 mm in thickness. Ulceration status: Without ulceration. T4b: Tumor measuring more than 4.0 mm in thickness. Ulceration status: With ulceration.  N0: No regional lymph node metastasis detected. Presence of in-transit, satellite, and/or microsatellite metastases: No. M0: No evidence of distant metastasis. LDH level is not applicable. (AJCC 8th ed.)


name: Grade 4 Thorax Soft Tissue Necrosis, CTCAE


name: HPV-Mediated (p16-Positive) Oropharyngeal Cancer Pathologic Distant Metastasis TNM Finding v8

description: A pathologic finding about one or more characteristics of HPV-mediated (p16-positive) oropharyngeal cancer, following the rules of the TNM AJCC v8 classification system as they pertain to distant metastases.


name: Chronic Eosinophilic Leukemia with FIP1L1-PDGFRA

description: Chronic eosinophilic leukemia characterized by the rearrangement of the PDGFRA gene, most often resulting in the formation of FIP1L1-PDGFRA fusion transcripts.


Suicidal Ideation, CTCAE

description: A disorder characterized by thoughts of taking one's own life.


name: Other Stimulant Dependence with Unspecified Stimulant-Induced Disorder

description: Evidence of other stimulant dependence with unspecified stimulant-induced disorder not specified elsewhere.


name: Rheumatoid Arthritis of Unspecified Hand with Involvement of Organs and Systems

description: Evidence of rheumatoid arthritis of unspecified hand with involvement of organs and systems.


name: Childhood Acute Lymphoblastic Leukemia by Toronto Guidelines v2

description: A term that refers to the staging of childhood acute lymphoblastic Leukemia according to the Toronto childhood cancer staging guidelines v2.


name: Grade 5 Social Circumstances - Other, Specify, CTCAE

description: Death


name: Other Stimulant Abuse with Stimulant-Induced Psychotic Disorder, Unspecified

description: Evidence of other stimulant abuse with stimulant-induced psychotic disorder not specified elsewhere.


name: Mucosal Melanoma of the Head and Neck TNM Finding v7

description: A finding about one or more characteristics of mucosal melanoma of the head and neck, following the rules of the TNM AJCC v7 classification system.


Angiosarcoma recurrent

description: The reemergence of angiosarcoma after a period of remission.


Glioblastoma by Gene Expression Profile

description: Classification of glioblastoma into molecular subtypes as defined by gene expression profiling.


Other Myeloid Leukemia in Relapse

description: Evidence of other myeloid leukemia in relapse not specified elsewhere.


Metastatic Midgut Neuroendocrine Tumor

description: A midgut neuroendocrine tumor that has spread from its original site of growth to another anatomic site.


Grade 1 Chylothorax, CTCAE

description: Asymptomatic; clinical or diagnostic observations only; intervention not indicated


name: Merkel Cell Carcinoma Clinical Regional Lymph Nodes TNM Finding v7

description: A clinical finding about one or more characteristics of Merkel cell carcinoma, following the rules of the TNM AJCC v7 classification system as they pertain to staging of regional lymph nodes.  The TNM clinical and pathologic regional lymph nodes classifications of Merkel cell carcinoma are not the same. TNM clinical regional lymph nodes findings are based on clinical inspection and palpation of the regional lymph nodes and/or radiologic studies. (from AJCC 7th Ed.)


Lung Cancer pT2 TNM Finding v8

description: Lung cancer with tumor measuring more than 3 cm but 5 cm or less in greatest dimension or having any of the following features: involves the main bronchus regardless of distance to the carina, but without involvement of the carina, invades visceral pleura (extends through the elastic layer-PL1 or extends to the surface of the visceral pleura-PL2), or is associated with atelectasis or obstructive pneumonitis that extends to the hilar region, involving part or all of the lung. T2 tumors with these features are classified as T2a if they measure 4 cm or less or if the size cannot be determined and T2b if they measure more than 4 cm but 5 cm or less in greatest dimension. (from AJCC 8th Ed.)


Fluid Discharge

description: The pouring forth of a fluid.


name: Grade 3 Uterus Stricture or Stenosis, CTCAE


Distal Bile Duct Cancer TNM Finding v7

description: A finding about one or more characteristics of distal bile duct cancer, following the rules of the TNM AJCC v7 classification system.  This TNM classification applies only to cancers arising in the extrahepatic bile ducts above the ampulla of Vater.  Sarcomas and carcinoid tumors are not included. (from AJCC 7th Ed.)


Stage III Anal Cancer AJCC v8

description: Stage III includes: IIIA: (T1, N1, M0); (T2, N1, M0); IIIB: (T4, N0, M0); IIIC: (T3, N1, M0); (T4, N1, M0). T1: Tumor 2 cm or smaller. T2: Tumor larger than 2 cm but equal to or smaller than 5 cm. T3: Tumor larger than 5 cm. T4: Tumor of any size invading adjacent organ(s), such as the vagina, urethra, or bladder. N0: No regional lymph node metastasis. N1: Metastasis in inguinal, mesorectal, internal iliac, or external iliac nodes. M0: No distant metastasis. (AJCC 8th ed.)


name: Renal Pelvis and Ureter Cancer pT3 TNM Finding v8

description: For renal pelvis only: Tumor invades beyond muscularis into peripelvic fat or into the renal parenchyma. For ureter only: Tumor invades beyond muscularis into periureteric fat. (from AJCC 8th Ed.)


name: Systemic lupus erythematosus with pericarditis

description: Evidence of pericarditis in systemic lupus erythematosus.


Photophobia, CTCAE 5.0

description: A disorder characterized by fear and avoidance of light.


name: Adrenal Cortical Carcinoma cM0 TNM Finding v8

description: No distant metastasis. (from AJCC 8th Ed.)


name: Rheumatoid Arthritis without Rheumatoid Factor, Unspecified Wrist

description: Evidence of rheumatoid arthritis without rheumatoid factor in an unspecified wrist.


name: Head and Neck Cancer pN3a TNM Finding v8

description: Head and neck cancer with metastasis in a lymph node larger than 6 cm in greatest dimension and ENE(-). (from AJCC 8th Ed.)


name: Acute and subacute infective endocarditis

description: Evidence of acute and subacute infective endocarditis.


Grade 1 Memory Impairment, CTCAE

description: Mild memory impairment


name: Grade 5 Spermatic Cord Perforation, CTCAE


Primary acquired melanosis

description: A spectrum of neoplastic changes that occur in the conjunctiva and range from melanocytic hyperplasia through degrees of atypia to melanoma in situ. The lesions are generally unilateral but often multifocal and appear as flat, irregular brown discolorations of the conjunctiva. They usually affect middle-aged and elderly Caucasians. (WHO 2018)


Meningeal Gliomatosis

description: Diffuse or multifocal infiltration of the meninges by malignant glioma.


Cervical Cancer Clinical TNM Finding v8

description: A clinical finding about one or more characteristics of cervical cancer, following the rules of the TNM AJCC v8 classification system.


name: Appendiceal Carcinoma pM1b TNM Finding v8

description: Appendiceal carcinoma with intraperitoneal metastasis only, including peritoneal mucinous deposits containing tumor cells. (from AJCC 8th Ed.)


Mediastinal Hemorrhage

description: Bleeding originating from the mediastinum.


name: Upper Airway Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils NOS, CTCAE


name: Carcinoma of the Lacrimal Gland pM1 TNM Finding v7

description: Carcinoma of the lacrimal gland with distant metastasis. (from AJCC 7th Ed.)


Grade 2 Middle Ear Inflammation, CTCAE

description: Serous otitis, medical intervention indicated


Grade 5 Hypoxia, CTCAE

description: Death


name: Unspecified Atherosclerosis of Other Type of Bypass Graft(s) of the Extremities, Left Leg

description: Evidence of unspecified atherosclerosis of other type of bypass graft(s) of the extremities in the left leg.


name: Intrahepatic Bile Duct Cancer pT2a TNM Finding v7

description: Intrahepatic bile duct cancer with solitary tumor with vascular invasion. (from AJCC 7th Ed.)


name: Grade 2 Biliary Tree Infection with Unknown Absolute Neutrophil Count, CTCAE


Gallbladder Goblet Cell Adenocarcinoma

description: An invasive mixed adenoneuroendocrine carcinoma of the gallbladder characterized by the presence of neoplastic signet-ring cells resembling goblet cells of the intestine.


name: Type 1 Diabetes Mellitus with Diabetic Amyotrophy

description: Evidence of type 1 diabetes mellitus with diabetic amyotrophy.


Post-Study Adverse Event

description: An adverse event that occurred after the patient had completed a clinical study (including any protocol-required post-treatment follow-up).


name: High Grade Prostatic Intraepithelial Neoplasia, Small Cell Neuroendocrine Variant

description: High grade prostatic intraepithelial neoplasia characterized by the presence of small neuroendocrine cells in the affected glands.


Breast Cancer cN2b TNM Finding v6

description: Breast cancer with metastasis only in clinically apparent ipsilateral internal mammary nodes and in the absence of clinically evident axillary lymph node metastasis. (from AJCC 6th Ed.)


name: Malignant Neoplasm of Connective and Soft Tissue of Right Upper Limb, Including Shoulder

description: Evidence of a malignant neoplasm of connective and soft tissue of right upper limb including the shoulder.


Grade 3 Uterine Infection, CTCAE

description: IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated


name: Body Mass Index Greater than or Equal to 30

description: Indicates a body mass index of 30 or higher.


name: Juvenile Rheumatoid Arthritis with Systemic Onset, Unspecified Elbow

description: Evidence of juvenile rheumatoid arthritis with systemic onset in an unspecified elbow.


name: Locally Advanced Ampulla of Vater Carcinoma

description: Carcinoma that arises from the ampulla of Vater and has spread to nearby tissues or lymph nodes.


Grade 4 Infantile Apnea, AE

description: An apneic adverse event in a newborn characterized by life-threatening respiratory and/or hemodynamic compromise; (semi-)urgent intubation required.


Intraoperative Respiratory Injury

description: Damage to the respiratory system during a surgical procedure.


Pleural Infection, CTCAE

description: A disorder characterized by an infectious process involving the pleura.


name: Grade 2 CNS Necrosis and Cystic Progression, CTCAE


Grade 5 Ileal Perforation, CTCAE

description: Death


Grade 3 Breast Pain, CTCAE

description: Severe pain; limiting self care ADL


name: Monomorphic Post-Transplant Lymphoproliferative Disorder

description: A clonal lymphoproliferative disorder arising as a result of post-transplant immunosuppression therapy. It is characterized by destructive infiltration of lymph nodes and extranodal sites by a monotonous population of transformed lymphocytes or plasma cells.  It includes two variants: monomorphic B-cell and monomorphic T/NK cell post-transplant lymphoproliferative disorders.


Grade 4 Respiratory Failure, CTCAE

description: Life-threatening consequences; urgent intervention, intubation, or ventilatory support indicated


Grade 4 Oral Hemorrhage, CTCAE

description: Life-threatening consequences; urgent intervention indicated


Retinoblastoma cT4a TNM Finding v7

description: Invasion of the optic nerve. (from AJCC 7th Ed.)


Abnormal Origin

description: An origin that is deviating from the norm or outwith the bounds of what is considered normal.


name: Colorectal Cancer pN0 TNM Finding v6 and v7

description: Colorectal cancer without regional lymph node metastasis. (from AJCC 6th and 7th Eds.)


name: Grade 1 Laryngopharyngeal Dysesthesia, CTCAE

description: Mild symptoms; no anxiety; intervention not indicated


Cervical Cancer pT0 TNM Finding v8

description: Cervical cancer with no evidence of primary tumor. (from AJCC 8th Ed.)


name: Grade 4 Lower Extremity Soft Tissue Necrosis, CTCAE


name: Conjunctival Melanoma cT3b TNM Finding v8

description: Conjunctival melanoma with tumor of any size invading the eyelid. (from AJCC 8th Ed.)


Grade 1 Spasticity, CTCAE

description: Mild or slight increase in muscle tone


Vaginal Cancer pT1 TNM Finding v7

description: Vaginal cancer with a tumor confined to vagina. (from AJCC 7th Ed.)


Contributory Cause of Death

description: A significant condition that is neither the immediate, intervening, originating, nor underlying cause of death but which contributed to the fatal outcome.


name: Grade 5 Trachea Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


Grade 3 Ovarian Infection, CTCAE

description: IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated


name: Grade 2 Lower Extremity Vein Intra-Operative Injury, CTCAE


CA19-9 Level Finding

description: A finding that indicates the amount of carbohydrate associated antigen (CA19.9) in a sample.


Kidney Cancer pT3c TNM Finding v6

description: Kidney cancer with tumor grossly extending into the vena cava above the diaphragm, or invading the wall of the vena cava. (from AJCC 6th Ed.)


name: Malignant Neoplasm of Unspecified Part of Right Adrenal Gland

description: Evidence of a malignant neoplasm of an unspecified part of right adrenal gland.


name: Pathologic Stage IV Retinoblastoma AJCC v8

description: Stage IV includes: Any pT, Any N, cM1 or pM1, Any H. cM1: Distant metastasis without microscopic confirmation. pM1: Distant metastasis with microscopic confirmation. HX: Unknown or insufficient evidence of a constitutional RB1 gene mutation. H0: Normal RB1 alleles in blood tested with demonstrated high-sensitivity assays. H1: Bilateral retinoblastoma, retinoblastoma with an intracranial primitive neuroectodermal tumor (i.e., trilateral retinoblastoma), patient with family history of retinoblastoma, or molecular definition of a constitutional RB1 gene mutation. (AJCC 8th ed.)


name: Anal Cancer Pathologic Distant Metastasis TNM Finding v6

description: A pathologic finding about one or more characteristics of anal cancer, following the rules of the TNM AJCC v6 classification system as they pertain to distant metastases.


EBV-Associated Smooth Muscle Tumor

description: A rare smooth muscle neoplasm of uncertain biological potential. It is associated with Epstein-Barr virus infection and seen in patients with immunodeficiency, including primary immunodeficiency, HIV/AIDS infection, and post-transplant immunosuppression.


name: Rheumatoid Heart Disease with Rheumatoid Arthritis of Right Hand

description: Evidence of rheumatoid heart disease with rheumatoid arthritis of right hand.


Grade 4 Portal Vein Thrombosis, CTCAE

description: Life-threatening consequences; urgent intervention indicated


name: Head and Neck Cancer cN3b TNM Finding v8

description: Head and neck cancer with metastasis in a single ipsilateral lymph node ENE(+); or metastases in multiple ipsilateral, contralateral, or bilateral lymph nodes, any with ENE(+). (from AJCC 8th Ed.)


name: Sedative, Hypnotic or Anxiolytic Induced Dependence with Intoxication, Uncomplicated

description: Evidence of sedative, hypnotic or anxiolytic induced dependence with intoxication, uncomplicated.


Recurrent Disease, Primary Site

description: Recurrence of symptoms of a disease at the original site.


Grade 5 Soft Tissue Infection, CTCAE

description: Death


name: Thoracic Duct Intra-Operative Injury, CTCAE


Cancer-Associated Pain

description: Pain associated with cancer or its diagnosis or treatment.


Grade 3 Bronchial Stricture, CTCAE

description: Shortness of breath with stridor; endoscopic intervention indicated (e.g., laser, stent placement)


name: Atherosclerosis of Unspecified Type of Bypass Graft(s) of Extremities with Intermittent Claudication, Right Leg

description: Evidence of atherosclerosis of unspecified type of bypass graft(s) of extremities with intermittent claudication in the right leg.


name: Unspecified Juvenile Rheumatoid Arthritis, Right Ankle and Foot

description: Evidence of unspecified juvenile rheumatoid arthritis in the right ankle and foot.


Locally Advanced Carcinoma

description: A carcinoma that has spread from its original site of growth to nearby tissues or lymph nodes.


name: Chest Pain Along Left Middle Sternal Border

description: The location of the chest pain is along the left middle border of the sternum.


name: Appendiceal Carcinoma cM1c TNM Finding v8

description: Appendiceal carcinoma with metastasis to sites other than peritoneum. (from AJCC 8th Ed.)


alcohol abuse - uncomplicated

description: Evidence of alcohol abuse, uncomplicated.


name: Diabetes Mellitus due to Underlying Condition with Mild Non-Proliferative Diabetic Retinopathy with Macular Edema

description: Evidence of diabetes mellitus due to underlying condition with mild non-proliferative diabetic retinopathy with macular edema.


name: Grade 1 Pharynx Intra-Operative Injury, CTCAE


Grade 5 Oral Cavity Fistula, CTCAE

description: Death


Myocardial degeneration

description: Degeneration of myocardial tissue.


name: Grade 2 Cervical Spine Range of Motion, CTCAE


Astler-Coller C2 Colon Carcinoma

description: Stage III includes: IIIA (T1-T2, N1, M0); IIIB (T3-T4, N1, M0); IIIC (Any T, N2, M0). N1: Metastasis in 1 to 3 regional lymph nodes.  N2: Metastasis in 4 or more regional lymph nodes. M0: No distant metastasis. (AJCC 6th ed.)


name: Postneoadjuvant Therapy Stage IVB Esophageal Adenocarcinoma AJCC v8

description: Stage IVB includes: Any T, Any N, M1. M1: Distant metastasis. (AJCC 8th ed.)


Gastrinoma, malignant

description: A gastrin-producing neuroendocrine tumor.  It is characterized by inappropriate secretion of gastrin and associated with Zollinger Ellison syndrome.  It displays vascular invasion and metastasizes to other anatomic sites.


name: Gastrointestinal Stromal Tumor TNM Finding v8

description: A finding about one or more characteristics of gastrointestinal stromal tumor (GIST), following the rules of the TNM AJCC v8 classification system. This classification system does not apply to pediatric GIST, familial GIST (germline mutant KIT or PDGFRA), or syndromic GIST (no AJCC staging system available). (from AJCC 8th Ed.)


name: Congenital Defects of Phagocyte Number, Function, or Both

description: A group of diseases or disorders caused by genetic defects within the immune system and comprising: Congenital neutropenia; Defects of motility; Defects of respiratory burst; and other nonlymphoid defects.


Neonatal Convulsion, AE

description: An adverse event in a newborn characterized by sudden, involuntary, rapid rhythmic or stereotyped skeletal muscular contraction.


Grade 1 Ovarian Rupture, CTCAE

description: Asymptomatic clinical or diagnostic observations only; intervention not indicated


name: Gestational Trophoblastic Neoplasm pM1 TNM Finding v8

description: Gestational trophoblastic neoplasm with distant metastasis. (from AJCC 8th Ed.)


name: Bladder Cancer Pathologic Distant Metastasis TNM Finding v8

description: A pathologic finding about one or more characteristics of bladder cancer, following the rules of the TNM AJCC v8 classification system as they pertain to distant metastases.


name: Colorectal Neuroendocrine Tumor pT1 TNM Finding v8

description: Colorectal neuroendocrine tumor invading the lamina propria or submucosa and measuring 2 cm or less. (from AJCC 8th Ed.)


Synchronous Lesion

description: Two or more primary lesions that are diagnosed at the same time in the same patient, or soon after the diagnosis of the first primary lesion.


Extracutaneous Dissemination of Disease

description: A finding indicating the presence of disease beyond the skin.


Megakaryocytic Neoplasm

description: A neoplasm affecting cells of the megakaryocytic lineage.


name: Other specified degenerative diseases of basal ganglia

description: Evidence of other specified degenerative diseases of basal ganglia not specified elsewhere.


Grade 4 Neonatal Convulsion, AE

description: An adverse event in a newborn characterized by suspected seizures with life-threatening consequences (e.g. need for ventilation); suspected status epilepticus (greater than 30 minutes of convulsions within any 60 minute period) despite multiple anti-seizure drugs.


Grade 1 Esophageal Obstruction, CTCAE

description: Asymptomatic; clinical or diagnostic observations only; intervention not indicated


name: Catheter-Related Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


Grade 2 Pyramidal Tract Syndrome, CTCAE

description: Moderate symptoms; limiting instrumental ADL


name: Malignant Neoplasm of Central Portion of Left Female Breast

description: Evidence of a malignant neoplasm of the central portion of left female breast.


name: Grade 1 Cranial Nerve IX Sensory Intra-Operative Injury, CTCAE


name: Grade 2 Larynx Mucositis or Stomatitis by Functional or Symptomatic Classification, CTCAE


name: Grade 1 Blood Lactate Dehydrogenase Increased, CTCAE

description: >ULN


name: Soft Tissue Sarcoma of the Trunk and Extremities cM1 TNM Finding v8

description: Soft tissue sarcoma of the trunk and extremities with distant metastasis. (from AJCC 8th Ed.)


Resin Fume Exposure

description: Environmental, occupational, or consumer-based exposure epoxy compounds and other volatile chemicals associated with production and handling of resins (liquid plastics).


Grade 3 Gastric Necrosis, CTCAE

description: Inability to aliment adequately by GI tract; invasive intervention indicated


name: Grade 2 Tongue Intra-Operative Injury, CTCAE


name: Cutaneous Melanoma pM1d(0) TNM Finding v8

description: Cutaneous melanoma with distant metastasis to CNS with or without M1a, M1b, or M1c sites of disease.  LDH level normal. (from AJCC 8th Ed.)


name: Melanoma in situ of eyelid, including canthus

description: Evidence of melanoma in situ of eyelid including the canthus.


Acidosis, CTCAE

description: A disorder characterized by abnormally high acidity (high hydrogen-ion concentration) of the blood and other body tissues.


name: Chronic Cutaneous Graft Versus Host Disease

description: Chronic graft versus host disease (GvHD) occurring in the skin.


Injury of bronchus

description: Trauma to the lung bronchi.


Prosthetic Complication

description: A problem arising from the use of a prosthetic.


EBV positive mucocutaneous ulcer

description: A rare Epstein-Barr virus-positive B-cell lymphoproliferative disorder that affects mucosal sites (including oral mucosa, palate, tonsils, and gastrointestinal tract) and skin. It presents with well-circumscribed, often painful ulcers. It is associated with immune suppression, including age-related and drug-induced immunosuppression. In the majority of cases the lesions regress either spontaneously or following withdrawal of the immunosuppression therapy.


Malignant melanoma in junctional nevus

description: A melanoma arising from a melanocytic nevus which involves the dermal-epidermal junction of the skin.


Negative Rechallenge Response

description: Failure of the product/drug, when reintroduced, to produce signs or symptoms similar to those observed when the product/drug was previously used.


name: Childhood Malignant Bone Neoplasm by Toronto Guidelines v2 Stage

description: A term that refers to the staging of childhood malignant bone neoplasm according to the Toronto childhood cancer staging guidelines v2. Staging is the same for both tiers (tier 1 and 2).


name: Peripheral Sensory Nerve NOS Intra-Operative Injury, CTCAE


name: Grade 5 Pleura Infection with Unknown Absolute Neutrophil Count, CTCAE


description: A rare mucinous cystadenocarcinoma that arises from the paratesticular structures.


name: Melanoma in situ of right lower eyelid, including canthus

description: Evidence of melanoma in situ of right lower eyelid including the canthus.


Increased anogenital distance

description: An indication that the anogenital distance is greater than the norm.


name: Grade 5 Pharynx Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


name: Grade 1 Serum Hypertriglyceridemia, CTCAE


name: Atherosclerosis of Other Type of Bypass Graft(s) of the Extremities with Rest Pain, Right Leg

description: Evidence of atherosclerosis of other type of bypass graft(s) of the extremities with rest pain in the right leg.


name: Rheumatic Multiple Valve Disease, Unspecified

description: Evidence of rheumatic multiple valve disease.