name: Mechanical Complication of Heart Valve Prosthesis, Subsequent Encounter

description: Evidence of mechanical complication of heart valve prosthesis, subsequent encounter.


category: biolink:Disease biolink:DiseaseOrPhenotypicFeature biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing

description: Evidence of hallucinogen dependence with hallucinogen-induced psychotic disorder.


name: Malignant neoplasm of pelvic bones, sacrum and coccyx

description: Evidence of a malignant neoplasm of the pelvic bones, sacrum and coccyx.


Dose Extravasation

category: biolink:PhenotypicFeature biolink:DiseaseOrPhenotypicFeature biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing

description: An artifact resulting from the leakage of an imaging agent from its location of administration.


Antepartum Obstetric Thromboembolism

description: Presence of a blood clot in the maternal vascular system which originated from a distant site during the antepartum period.


Tumor Regression Absent

description: A response that the tumor regression is absent.


name: Grade 4 Rectum Infection with Unknown Absolute Neutrophil Count, CTCAE


name: Squamous intraepithelial neoplasia grade 2


name: Left Posteromedial Apical Peripheral Zone of Prostate

description: The region of the prostate that is located on the anatomical left side of the posteromedial portion of the apical division of the peripheral zone.


Grade 3 Penile Infection, CTCAE

description: IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated


name: Direct Infection of Unspecified Hip in Infectious and Parasitic Diseases Classified Elsewhere

description: Evidence of direct infection of unspecified hip in infectious and parasitic diseases classified elsewhere.


name: Cutaneous Squamous Cell Carcinoma of the Head and Neck cN3b TNM Finding v8

description: Cutaneous squamous cell carcinoma of the head and neck with metastasis in any lymph node(s) and ENE(+). (from AJCC 8th Ed.)


Platinum-Sensitive Disease

description: A finding indicating that a cancer responds to platinum therapy initially, but it comes back after a certain period. For ovarian cancer, it refers to cancer relapse at least six months after the end of platinum therapy.


name: Grade 2 Vascular Disorders - Other, Specify, CTCAE

description: Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL


Grade 4 Myelitis, CTCAE

description: Life-threatening consequences; urgent intervention indicated


Breast Cancer cN2 TNM Finding v6

description: Breast cancer with metastases in ipsilateral axillary lymph nodes fixed or matted, or in clinically apparent ipsilateral internal mammary nodes in the absence of clinically evident axillary lymph node metastasis. (from AJCC 6th Ed.)


name: Carcinoma of the Eyelid pT3b TNM Finding v7

description: Carcinoma of the eyelid for which complete tumor resection requires enucleation, exenteration, or bone resection.  (from AJCC 7th Ed.)


name: Good Prognosis Metastatic Gestational Trophoblastic Tumor

description: Metastatic gestational trophoblastic tumor in which risk factors are absent.


Urothelial carcinoma urethra recurrent

description: The reemergence of urethral urothelial carcinoma after a period of remission.


Satellite Nodule

description: Additional, separate neoplastic nodules surrounding a central neoplastic lesion.


Stage 0 Testicular Cancer AJCC v8

description: Stage 0 includes: pTis, N0, M0, S0. pTis: Testicular cancer with a finding of germ cell neoplasia in situ. N0: Testicular cancer with no regional lymph node metastasis. M0: Testicular cancer without evidence of distant metastasis. S0: Marker study levels within normal limits. (AJCC 8th ed.)


name: Localized Childhood Retinoblastoma by Toronto Guidelines v2

description: Intraocular tumor. (Childhood cancer staging for population registries according to the Toronto Childhood Cancer Stage Guidelines - Version 2. Cancer Council Queensland and Cancer Australia: Brisbane, Australia; 2021.)


name: Large Intestinal Anastomotic Leak, CTCAE

description: A finding of leakage due to breakdown of an anastomosis (surgical connection of two separate anatomic structures) in the large intestine.


name: Grade 4 Cecum Infection with Unknown Absolute Neutrophil Count, CTCAE


name: Merkel Cell Carcinoma cT1 TNM Finding v8

description: Merkel cell carcinoma with maximum clinical tumor diameter equal to or less than 2 cm. (from AJCC 8th Ed.)


name: Grade 2 Cranial Nerve VII Neuropathy, CTCAE


name: Grade 5 Peritoneal Cavity Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


Cervical meningomyelocele

description: A congenital abnormality in the cervical region of the spine in which the spinal cord and meninges protrude through a defect in the spinal column. The protrusion is above the skin surface.


name: Refractory Monomorphic Post-Transplant Lymphoproliferative Disorder

description: A monomorphic post-transplant lymphoproliferative disorder that does not respond to treatment.


name: Burkitt's lymphoma of lymph nodes of multiple sites

description: Evidence of Burkitt lymphoma in the lymph nodes of multiple sites.


Grade 1 Urine Discoloration, CTCAE

description: Present


name: Pancreatic Endocrine Glucose Intolerance, CTCAE


Grade 3 Hypocalcemia, CTCAE

description: Corrected serum calcium of <7.0-6.0 mg/dL; <1.75-1.5 mmol/L; Ionized calcium <0.9-0.8 mmol/L; hospitalization indicated


Mutation-Negative Lynch Syndrome

description: A finding of Lynch syndrome in which one is identified as having a "non-sporadic" DNA mismatch repair (MMR) deficient premalignant lesion or "non-sporadic" MMR deficient malignant tumor, but germline MMR genetic testing did not demonstrate a recognized pathogenic mutation in the genes responsible for DNA mismatch repair.


name: Serum Immunoglobulin Free Light Chain Ratio Abnormal

description: A laboratory test result indicating an abnormal kappa to lambda ratio of immunoglobulin free light chains in the serum.


name: Grade 4 Thrombotic Microangiopathy, CTCAE


name: Grade 5 Cranial Nerve I Neuropathy, CTCAE


Encephalopathy Related to COVID-19

description: Encephalopathy in a patient with probable or confirmed acute COVID-19.


name: Left Anterior Basal Transition Zone of Prostate

description: The region of the prostate that is located on the anatomical left side of the anterior portion of the basal division of the transition zone.


Cutaneous Melanoma pNX TNM Finding v8

description: Cutaneous melanoma in which the regional lymph nodes are not assessed (e.g., sentinel lymph node biopsy is not performed, regional lymph nodes were previously removed for another reason). Exception: pathological N category is not required for T1 melanomas, use cN. Presence of in-transit, satellite, and/or microsatellite metastases: No.  (from AJCC 8th Ed.)


Progesterone Receptor Status 0

description: An immunohistochemical result of 0 for progesterone receptor expression that is considered negative for expression.


name: Duodenum/Ampulla/Jejunum/Ileum Neuroendocrine Tumor pN1 TNM Finding v7

description: Duodenum/ampulla/jejunum/ileum neuroendocrine tumor with regional lymph node metastasis. (from AJCC 7th Ed.)


name: Stage IIA Pancreatic Cancer AJCC v6 and v7

description: Stage IIA includes: T3, N0, M0.  T3: Tumor extends beyond the pancreas but without involvement of the celiac axis or the superior mesenteric artery.  N0: No regional lymph node metastasis.  M0: No distant metastasis. (from AJCC 7th Ed.)


Grade 5 Adrenal Insufficiency, CTCAE

description: Death


name: Grade 2 Peripheral Nerve Infection, CTCAE

description: Localized; local intervention indicated (e.g., topical antibiotic, antifungal, or antiviral)


Grade 3 Neonatal Bradyarrhythmia, AE

description: A bradyarrhythmia adverse event in a newborn resulting in non-life threatening hemodynamic compromise; requiring major care changes (e.g. new medication or intervention).


name: Appendix Neuroendocrine Tumor Pathologic TNM Finding v8

description: A pathologic finding about one or more characteristics of an appendiceal neuroendocrine tumor, following the rules of the TNM AJCC v8 classification system.


name: Oropharyngeal (p16-Negative) Cancer cN3b TNM Finding v8

description: Oropharyngeal (p16-negative) cancer with metastasis in any node(s) and clinically overt ENE(+). (from AJCC 8th Ed.)


name: Maxillary Sinus Cancer pN2 TNM Finding v7

description: Maxillary sinus cancer with metastasis in a single ipsilateral lymph node, more than 3 cm but not more than 6 cm in greatest dimension, or in multiple ipsilateral lymph nodes, none more than 6 cm in greatest dimension, or in bilateral or contralateral lymph nodes, none more than 6 cm in greatest dimension. (from AJCC 7th Ed.)


Retinoblastoma pM1a TNM Finding v8

description: Retinoblastoma with pathological evidence of tumor at any distant site (e.g., bone marrow, liver, or other). (from AJCC 8th Ed.)


Grade 3 Neonatal Hypotension, AE

description: An adverse event in a newborn characterized by persistent hypotension affecting perfusion; requiring major care change (e.g. vaso-active drugs or hydrocortisone).


name: Malignant Melanoma of Left Upper Limb, Including Shoulder

description: Evidence of a malignant melanoma of the left upper limb including the shoulder.


name: Leiomyosarcoma and Endometrial Stromal Sarcoma pT1b TNM Finding v7

description: Tumor more than 5 cm in greatest dimension. (from AJCC 7th Ed.)


name: Nasal Cavity and Ethmoid Sinus Cancer Clinical Distant Metastasis TNM Finding v7

description: A clinical finding about one or more characteristics of nasal cavity and ethmoid sinus cancer, following the rules of the TNM AJCC v7 classification system as they pertain to distant metastases.


Intoxication

description: Disturbances in psychophysiological functions and responses as a result of administration or ingestion of a psychoactive substance.


Retinoblastoma cT3b TNM Finding v7

description: One or more complications are present, which may include tumor-associated neovascular or angle closure glaucoma, tumor extension into the anterior segment, hyphema, vitreous hemorrhage, or orbital cellulitis. (from AJCC 7th Ed.)


name: Postneoadjuvant Therapy Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8

description: Stage III includes: IIIA: (T0-2, N1, M0); IIIB: (T3, N1, M0); (T0-3, N2, M0); (T4a, N0, M0). T0: No evidence of primary tumor. T1: Tumor invades the lamina propria, muscularis mucosae, or submucosa. T2: Tumor invades the muscularis propria. T3: Tumor invades adventitia. T4a: Tumor invades the pleura, pericardium, azygos vein, diaphragm, or peritoneum. N0: No regional lymph node metastasis. N1: Tumor with metastasis in one or two regional lymph nodes. N2: Tumor with metastasis in three to six regional lymph nodes. M0: No distant metastasis. (AJCC 8th ed.)


Grade 2 Burn, CTCAE

description: Medical intervention; minimal debridement indicated


Grade 1 Perineal Pain, CTCAE

description: Mild pain


Non-Neoplastic Hepatobiliary Disorder

description: A non-neoplastic disorder that affects the liver, bile ducts, and gallbladder. Representative examples include hepatitis, cirrhosis, cholangitis, and cholecystitis.


name: Locally Advanced Digestive System Neuroendocrine Tumor G2

description: Digestive system neuroendocrine tumor G2 that has spread from its original site of growth to nearby tissues or lymph nodes.


Hypophosphatemia, CTCAE

description: A disorder characterized by laboratory test results that indicate a low concentration of phosphates in the blood.


Induced cataract

description: A cataract that has been produced artificially or by induction, e.g. as a result of device use, medication, trauma, tears, falls, accidental injury, etc.


Stage IA Vulvar Cancer AJCC v7

description: Stage IA includes: T1a, N0, M0. T1a: Tumor confined to the vulva and perineum, 2 cm or less in greatest dimension, and with stromal invasion no greater than 1 mm.  N0: No regional lymph node metastasis.  M0: No distant metastasis. (AJCC 7th ed.)


name: Gastric Neuroendocrine Tumor pNX TNM Finding v8

description: Gastric neuroendocrine tumor in which the regional lymph nodes cannot be assessed.  (from AJCC 8th Ed.)


name: Grade 5 CNS Necrosis and Cystic Progression, CTCAE


name: Subglottic Cancer Pathologic Primary Tumor TNM Finding v8

description: A pathologic finding about one or more characteristics of subglottic cancer, following the rules of the TNM AJCC v8 classification system as they pertain to staging of the primary tumor.


name: Metastatic Extrapulmonary Neuroendocrine Carcinoma

description: Extrapulmonary neuroendocrine carcinoma that has spread to another anatomic site.


name: Atherosclerosis of Unspecified Type of Bypass Graft(s) of the Extremities with Gangrene, Unspecified Extremity

description: Evidence of atherosclerosis of unspecified type of bypass graft(s) of the extremities with gangrene in the unspecified extremity.


name: Recurrent Digestive System Neuroendocrine Tumor G1

description: The reemergence of digestive system neuroendocrine tumor G1 after a period of remission.


name: Arthropathy following Intestinal Bypass, Left Hip

description: Evidence of arthropathy following intestinal bypass in the left hip.


FGFR1 Gene Rearrangement Negative

description: A genetic finding indicating that rearrangement of the FGFR1 gene has not been detected in a sample.


name: Atrioventricular Block First Degree, CTCAE

description: A disorder characterized by a dysrhythmia with a delay in the time required for the conduction of an electrical impulse through the atrioventricular (AV) node beyond 0.2 seconds; prolongation of the PR interval greater than 200 milliseconds.


name: Atherosclerosis of Autologous Vein Bypass Graft(s) of Left Leg with Ulceration of Heel and Midfoot

description: Evidence of atherosclerosis of autologous vein bypass graft(s) of left leg with ulceration of heel and midfoot.


name: Unspecified Type of Carcinoma in Situ of Right Breast

description: Evidence of unspecified type of carcinoma in situ of right breast.


name: Adrenal Cortical Carcinoma pM1 TNM Finding v8

description: Distant metastasis. (from AJCC 8th Ed.)


name: Melanoma in situ of left upper eyelid, including canthus

description: Evidence of melanoma in situ of left upper eyelid including the canthus.


Grade 2 Pleuritic Pain, CTCAE

description: Moderate pain; limiting instrumental ADL


Grade 5 Bone Marrow Hypocellular, CTCAE

description: Death


Grade 3 Fetal Growth Retardation, CTCAE

description: <5% percentile of weight for gestational age


name: Clinical Stage IIB Esophageal Adenocarcinoma AJCC v8

description: Stage IIB includes: T2, N0, M0. T2: Tumor invades the muscularis propria. N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 8th ed.)


name: Rheumatoid Heart Disease with Rheumatoid Arthritis of Unspecified Elbow

description: Evidence of rheumatoid heart disease with rheumatoid arthritis of unspecified elbow.


name: Exocrine Pancreatic Cancer pT2 TNM Finding v8

description: Exocrine pancreatic cancer with tumor measuring more than 2 cm and 4 cm or less in greatest dimension. (from AJCC 8th Ed.)


Esophageal Neuroendocrine Tumor G1

description: A rare, well differentiated, low grade neoplasm with neuroendocrine differentiation that arises from the esophagus. The mitotic count is less than 2 per 10 HPF and/or the Ki67 index is equal to or less than 2 percent. The majority of cases have a polypoid appearance, are small lesions, and found incidentally.


name: Grade 3 Intraoperative Breast Injury, CTCAE

description: Complete resection or reconstruction of injured organ/structure indicated; limiting self care ADL


enteropathic arthropathy wrist

description: Evidence of enteropathic arthropathies in an unspecified wrist.


name: Grade 4 Bronchopulmonary Hemorrhage NOS, CTCAE


Grade 4 Urethral Infection, CTCAE

description: Life-threatening consequences; urgent intervention indicated


name: Grade 3 Mediastinum Intra-Operative Injury, CTCAE


Thoracic Injuries

description: Trauma to the chest.


Morphologic Leukemia-Free State

description: The disappearance of all cells with morphologic characteristics of leukemia, accompanied by bone marrow recovery, in response to treatment. Hematologic recovery is not required. Leukemia free state can be a hypocellular marrow.


name: Mechanical Breakdown of Heart Valve Prosthesis, Initial

description: Evidence of mechanical breakdown of heart valve prosthesis, initial.


name: Transcription Factor-Associated Monogenic Diabetes

description: Monogenic diabetes caused by inactivating mutation(s) in transcription factors regulating expression of pancreatic beta cell genes.


name: Grade 3 Flashing Lights and Floaters in Vision, CTCAE


name: HPV-Mediated (p16-Positive) Oropharyngeal Cancer Pathologic TNM Finding v8

description: A pathologic finding about one or more characteristics of HPV-mediated (p16-positive) oropharyngeal cancer, following the rules of the TNM AJCC v8 classification system.


name: Bradyarrhythmia Related to COVID-19 Requiring Temporary or Permanent Pacing

description: Bradycardia (ventricular rate less than 60 bpm) showing signs of hypoperfusion and that requires temporary or permanent pacemaker intervention in a patient with probable or confirmed acute COVID-19.


name: Vaginal intraepithelial neoplasia grade 2

description: Vaginal intraepithelial neoplasia characterized by the presence of nuclear intraepithelial neoplastic changes in the lower two-thirds of the epithelium and parakeratosis.


Respirable Crystalline Silica Exposure

description: Environmental, occupational or consumer-based exposure to respirable particles derived from industrial processing or breakdown of silica-containing materials such as sand, concrete, stone, mortar, bricks,  glass, pottery and ceramics.


name: Supraglottic Cancer pN3 TNM Finding v6 and v7

description: Supraglottic cancer with metastasis in a lymph node, more than 6 cm in greatest dimension. (from AJCC 6th and 7th Eds.)


Anemia due to Increased Destruction

description: Anemia that results from an increased rate of erythrocyte destruction.


Grade 4 Fetal Growth Retardation, CTCAE

description: <1% percentile of weight for gestational age


name: Rheumatoid Vasculitis with Rheumatoid Arthritis of Right Elbow

description: Evidence of rheumatoid vasculitis with rheumatoid arthritis of right elbow.


name: Grade 4 Adrenal Gland Intra-Operative Injury, CTCAE


Grade 2 Serum Amylase Increased, CTCAE

description: >1.5-2.0 x ULN; >2.0-5.0 x ULN and asymptomatic


name: Atherosclerosis of Non-Autologous Biological Bypass Graft(s) of the Extremities with Intermittent Claudication, Bilateral Legs

description: Evidence of atherosclerosis of non-autologous biological bypass graft(s) of the extremities with intermittent claudication in both legs.


name: Nasopharyngeal Cancer pN3b TNM Finding v7

description: Nasopharyngeal cancer with extension to the supraclavicular fossa. Supraclavicular zone or fossa is relevant to the staging of nasopharyngeal carcinoma and is the triangular region originally described by Ho.  It is defined by three points: (1) the superior margin of the sternal end of the clavicle, (2) the superior margin of the lateral end of the clavicle, (3) the point where the neck meets the shoulder.  This would include caudal portions of levels IV and VB.  All cases with lymph nodes (whole or part) in the fossa are considered N3b. (from AJCC 7th Ed.)


name: Drug or Chemical Induced Diabetes Mellitus with Severe Non-Proliferative Diabetic Retinopathy with Macular Edema, Bilateral

description: Evidence of drug or chemical induced diabetes mellitus with severe non-proliferative diabetic retinopathy with macular edema that is bilateral.


Grade 3 Neonatal Sinus Tachycardia, AE

description: An adverse event in a newborn characterized by persistent sinus tachycardia; resulting in non-life threatening hemodynamic compromise; requiring major care changes (e.g. new medication or intervention).


Acute pericarditis

description: Acute inflammation of the pericardium.


Skin squamous cell carcinoma recurrent

description: The reemergence of squamous cell carcinoma of the skin after a period of remission.


name: Grade 2 Rectal Varices Hemorrhage, CTCAE


name: Platinum-Refractory Fallopian Tube High Grade Serous Adenocarcinoma

description: Fallopian tube high-grade serous adenocarcinoma that progresses during platinum therapy or within one month of completing platinum therapy.


name: Mucosal Melanoma of the Head and Neck cM0 TNM Finding v7

description: Mucosal melanoma of the head and neck without evidence of distant metastasis. (from AJCC 7th Ed.)


name: Rheumatoid Arthritis without Rheumatoid Factor, Multiple Sites

description: Evidence of rheumatoid arthritis without rheumatoid factor in multiple sites.


Grade 3 Esophageal Necrosis, CTCAE

description: Inability to aliment adequately by GI tract; invasive intervention indicated


Grade 1 Hyperparathyroidism, CTCAE

description: Mild symptoms; intervention not indicated


name: Grade 4 Jejunum Infection with Unknown Absolute Neutrophil Count, CTCAE


name: Other Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma, Lymph Nodes of Head, Face, and Neck

description: Evidence of other mature T-cell and NK-cell non-Hodgkin lymphoma in the lymph nodes of head in the face in the and neck not specified elsewhere.


name: Duodenum/Ampulla/Jejunum/Ileum Neuroendocrine Tumor cM1 TNM Finding v7

description: Duodenum/ampulla/jejunum/ileum neuroendocrine tumor with distant metastasis. (from AJCC 7th Ed.)


Grade 2 Testicular Hemorrhage, CTCAE

description: Moderate symptoms; intervention indicated


Stage IVA Cervical Cancer FIGO 2009

description: Cervical carcinoma with rectal or bladder involvement. (FIGO 2009)


Viral gastroenteritis

description: Gastroenteritis resulting from a viral infection.


Grade 5 Methemoglobinemia, CTCAE

description: Death


name: Human Papillomavirus-Related Malignant Neoplasm

description: A malignant neoplasm associated with the presence of human papillomavirus infection.


Grade 2 Amenorrhea, CTCAE

description: Present


name: Major Salivary Gland Cancer pT4a TNM Finding v6

description: Major salivary gland cancer with tumor invading the skin, mandible, ear canal, and/or facial nerve. (from AJCC 6th Ed.)


XK Negative

description: An indication that XK expression has not been detected in a sample.


Upper GI Partial Response GvHD

description: An NIH upper GI score that has decreased by 1 or more points.


Acral Lesion

description: A lesion that arises in a peripheral site (e.g., limbs, fingers, or ears).


Metaplastic carcinoma

description: A general term used to describe carcinomas arising from epithelial cells that have been transformed into another cells type (metaplastic epithelial cells). A representative example is the adenocarcinoma arising in Barrett esophagus. This term is also used to describe carcinomas in which the malignant epithelial cells show differentiation towards another cell type. A representative example of the latter is the metaplastic breast carcinoma in which the malignant glandular cells show squamous, spindle cell, or chondroid/osseous differentiation.


Foveolar-Type Adenoma

description: A rare neoplastic polyp that arises from the stomach.  It is characterized by the presence of foveolar-type epithelium.  It may be seen in patients with familial adenomatous polyposis.


Grade 4 Portal Hypertension, CTCAE

description: Life-threatening consequences; urgent intervention indicated


Other specified leukemias, in relapse

description: Evidence of other specified leukemias, in relapse not specified elsewhere.


name: Grade 3 Catheter-Related Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


Avascular joint necrosis

description: Death of bone tissue in a joint due to temporary or permanent interruption of blood flow.


name: Grade 3 Joint Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


name: Fluency Disorder following Other Cerebrovascular Disease

description: Evidence of fluency disorder following other cerebrovascular disease.


Occult Umbilical Cord Prolapse

description: A situation in which the umbilical cord is prolapsed through the cervical canal but not through external os.


Unresectable Malignant Mesothelioma

description: Malignant mesothelioma that is not amenable to surgical resection.


name: Gastric Neuroendocrine Tumor pT2 TNM Finding v8

description: Gastric neuroendocrine tumor invading the muscularis propria or is greater than 1 cm in size. (from AJCC 8th Ed.)


name: Grade 5 Intraoperative Hemorrhage, CTCAE

description: Death


Classic Type Trichilemmoma

description: Trichilemmoma in which there is no evidence of sclerotic stroma formation.


name: spondylopathy in diseases classified elsewhere in sacral and sacrococcygeal region

description: Evidence of spondylopathy in diseases classified elsewhere in the sacral and sacrococcygeal region.


name: Vulva Infection with Unknown Absolute Neutrophil Count, CTCAE


Small Cell Adenocarcinoma

description: An adenocarcinoma composed of small malignant cells.


Other Reactive Arthropathies, Left Hip

description: Evidence of other reactive arthropathies in the left hip not specified elsewhere.


Pulmonary Edema, CTCAE

description: A disorder characterized by accumulation of fluid in the lung tissues that causes a disturbance of the gas exchange that may lead to respiratory failure.


name: Other Paralytic Syndrome following Other Cerebrovascular Disease Affecting Left Non-Dominant Side

description: Evidence of other paralytic syndrome following other cerebrovascular disease affecting left non-dominant side not specified elsewhere.


Grade 3 Productive Cough, CTCAE

description: Persistent or copious production of sputum; limiting self care ADL


Grade 1 Gait Disturbance, CTCAE

description: Mild change in gait (e.g., wide-based, limping or hobbling)


name: Wound Infection with Unknown Absolute Neutrophil Count, CTCAE


Non-Congenital Amegakaryocytosis

description: An acquired non-neoplastic disorder characterized by marked reduction or absence of megakaryocytes and thrombocytopenia.


BRAF Gene Rearrangement Negative

description: A genetic finding indicating that rearrangement of the BRAF gene has not been detected in a sample.


Imperforate Vagina

description: A congenital birth defect characterized by the absence of a normal vaginal opening.


name: Grade 1 Brachial Plexus Intra-Operative Injury, CTCAE


PSA Level 0.1 to 50

description: A blood concentration of prostate specific antigen between 0.1 and 50 ng/mL.


name: Grade 3 Cranial Nerve X Neuropathy, CTCAE


Breast Cancer cT1 TNM Finding v6

description: Breast cancer with tumor size 2.0 cm or less in greatest dimension. (from AJCC 6th Ed.)


pT2c TNM Finding

description: A pathologic primary tumor TNM finding. The definition of pT2c finding depends on the particular type of cancer that it refers to; for example, for prostate cancer, pT2c finding is defined as follows: cancer involving both lobes of the prostate gland; for fallopian tube cancer, pT2c finding is defined as follows: cancer with pelvic extension and malignant cells in ascites or peritoneal washings. (from AJCC 7th Ed.)


Hoarseness, CTCAE

description: A disorder characterized by harsh and raspy voice arising from or spreading to the larynx.


name: Stage IIIC Uterine Corpus Cancer AJCC v7

description: Stage IIIC includes: IIIC1 (T1-T3, N1, M0); IIIC2 (T1-T3, N2, M0). T1: Tumor confined to corpus uteri.  T2: Tumor invades stromal connective tissue of the cervix but does not extend beyond uterus.  Endocervical glandular involvement only should be considered as Stage I and not as Stage II. T3: Tumor involves serosa and/or adnexa, vagina, or parametrial tissue. N1: Regional lymph node metastasis to pelvic lymph nodes. N2: Regional lymph node metastasis to para-aortic lymph nodes, with or without positive pelvic lymph nodes.  M0: No distant metastasis. This staging applies to carcinomas and carcinosarcomas. (AJCC 7th ed.)


name: Ocular Adnexal Lymphoma pT4a TNM Finding v7

description: Involvement of nasopharynx.  (from AJCC 7th Ed.)


name: Non-Traumatic Subarachnoid Hemorrhage from Other Intracranial Artery

description: Evidence of non-traumatic subarachnoid hemorrhage from other intracranial artery.


Puncture wound

description: Disruption of tissue caused by a pointed object.


name: Grade 4 Middle Ear Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


name: Central Nervous System Erdheim-Chester Disease

description: Erdheim-Chester disease that affects the central nervous system.


name: Arthropathy following Intestinal Bypass, Right Wrist

description: Evidence of arthropathy following intestinal bypass in the right wrist.


Post-infectious hypothyroidism

description: Evidence of post-infectious hypothyroidism.


name: Grade 1 Glossopharyngeal Nerve Disorder, CTCAE

description: Asymptomatic; clinical or diagnostic observations only; intervention not indicated


Recurrent Laryngeal Nerve Injuries

description: Damage to the recurrent laryngeal nerve.


Bone Cancer pNX TNM Finding v8

description: Bone cancer in which the regional lymph nodes cannot be assessed.  (from AJCC 8th Ed.)


Pancreatic Duct Stenosis, CTCAE

description: A disorder characterized by a narrowing of the lumen of the pancreatic duct.


name: Hepatobiliary Disorders - Other, Specify, CTCAE


Breast Cancer pT4d TNM Finding v8

description: Breast cancer meeting the criteria of inflammatory carcinoma. (from AJCC 8th Ed.)


name: Hemiplegia following Cerebral Infarction Affecting Unspecified Side

description: Evidence of hemiplegia following cerebral infarction affecting unspecified side.


Stage I Appendix Carcinoma AJCC v8

description: Stage I includes: (T1, N0, M0); (T2, N0, M0). T1: Tumor invades the submucosa (through the muscularis mucosa but not into the muscularis propria). T2: Tumor invades the muscularis propria. N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 8th ed.)


Grade 3 Kidney Infection, CTCAE

description: IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated


Testicular Cancer pT0 TNM Finding v7

description: No evidence of primary tumor (e.g., histologic scar in testis). (from AJCC 7th Ed.)


name: Lip or Perioral Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


name: Malignant Neoplasm of Scapula and Long Bones of Left Upper Limb

description: Evidence of a malignant neoplasm of the scapula and long bones of left upper limb.


Grade 2 Skin Hypopigmentation, CTCAE

description: Hypopigmentation or depigmentation covering >10% BSA; associated psychosocial impact


name: Grade 1 Glomerular Filtration Rate, CTCAE


Other encephalopathy

description: Evidence of other encephalopathy not specified elsewhere.


name: Nasal Cavity and Paranasal Sinuses Cancer pN2b TNM Finding v8

description: Nasal cavity and paranasal sinuses cancer with metastases in multiple ipsilateral lymph nodes, none larger than 6 cm in greatest dimension and ENE(-). (from AJCC 8th Ed.)


Malignant Vipoma

description: An aggressive neuroendocrine tumor located in the pancreas or small intestine. It is composed of cells containing vasoactive intestinal peptide.  It is associated with watery diarrhea, hypokalemia, and hypochlorhydria or achlorhydria. It displays vascular invasion and metastasizes to other anatomic sites.


description: Evidence of cocaine dependence with cocaine-induced psychotic disorder with hallucinations.


name: Intrahepatic Bile Duct Cancer pT1b TNM Finding v8

description: Intrahepatic bile duct cancer with solitary tumor larger than 5 cm without vascular invasion. (from AJCC 8th Ed.)


Not Otherwise Specified Lesion

description: A lesion in which further histopathological and/or molecular characterization is not possible, available, or reported.


Squamoid eccrine ductal carcinoma

description: A variant of ductal eccrine carcinoma with squamoid metaplasia.


name: T Acute Lymphoblastic Leukemia with Recurrent Genetic Abnormalities

description: T-acute lymphoblastic leukemias characterized by the presence of recurring cytogenetic and/or molecular abnormalities.


name: Diffuse Pediatric-Type High Grade Glioma RTK1

description: An aggressive, WHO grade 4 diffuse glioma usually affecting children, adolescents, or young adults. It is characterized by receptor tyrosine kinase type 1 (RTK1) alterations.


name: Malignant Neoplasm of Left Testis, Unspecified whether Descended or Undescended

description: Evidence of a malignant neoplasm of the left testis, unspecified whether descended or undescended.


Stage IVA Vulvar Cancer AJCC v7

description: Stage IVA includes: (T1/T2, N3, M0); (T3, Any N, M0).  T1: Invasive vulvar cancer confined to the vulva or perineum.  T2: Vulvar cancer with tumor of any size with extension to adjacent perineal structures (lower/distal 1/3 urethra, lower/distal 1/3 vagina, anal involvement).  T3: Vulvar cancer with tumor of any size with extension to any of the following: upper/proximal 2/3 urethra, upper/proximal 2/3 vagina, bladder mucosa, rectal mucosa, or fixed to pelvic bone.  N3: Vulvar cancer with fixed or ulcerated regional lymph node metastasis.  M0: No distant metastasis.  (AJCC 7th ed.)


Grade 2 Laryngeal Hemorrhage, CTCAE

description: Moderate symptoms; intervention indicated


Lung Cancer pNX TNM Finding v6 and v7

description: Lung cancer in which regional lymph nodes cannot be assessed. (from AJCC 6th and 7th Eds.)


Grade 3 Aspiration, CTCAE

description: Dyspnea and pneumonia symptoms (e.g., aspiration pneumonia); hospitalization indicated; unable to aliment orally


Grade 5 Postoperative Hemorrhage, CTCAE

description: Death


description: A pancreatic lesion microscopically resembling pancreatic intraepithelial neoplasia-1A, however the neoplastic nature of the pathologic process has not been unambiguously established.


name: Stenosis of Gastrointestinal Stoma, CTCAE

description: A finding of narrowing of the gastrointestinal stoma (surgically created opening on the surface of the body).


Grade 3 Genital Edema, CTCAE

description: Lymphorrhea; gross deviation from normal anatomic contour; limiting self care ADL


name: Grade 5 General Disorders and Administration Site Conditions - Other, Specify, CTCAE

description: Death


Complaint

description: A symptom or problem for which a patient seeks medical attention.


name: Mycosis Fungoides and Sezary Syndrome B1a TNM Finding v7

description: Clone negative.  Note: A T-cell clone is defined by PCR or Southern blot analysis of the T-cell receptor gene.  (from AJCC 7th Ed.)


PSA Level Less than Twenty

description: A blood concentration of prostate specific antigen less than 20 ng/mL.


Refractory Primary Myelofibrosis

description: Primary myelofibrosis that is resistant to treatment.


name: Ovarian, Fallopian Tube, and Primary Peritoneal Carcinoma pNX TNM Finding v8

description: Ovarian, fallopian tube, or primary peritoneal carcinoma in which the regional lymph nodes cannot be assessed. (from AJCC 8th Ed.)


Cecum Ulcer, CTCAE

description: Cecum Ulcer that is temporally associated with the use of a medical treatment or procedure, and that may or may not be considered related to the medical treatment or procedure.


Congenital absence of uterus

description: A congenital abnormality characterized by the complete absence of the uterus.


Other acute rheumatic heart disease

description: Evidence of other acute rheumatic heart disease not specified elsewhere.


name: Direct Infection of Right Shoulder in Infectious and Parasitic Diseases Classified Elsewhere

description: Evidence of direct infection of right shoulder in infectious and parasitic diseases classified elsewhere.


name: Vaso-Occlusive Crisis in Sickle Cell-Hemoglobin C Disease

description: Sickle cell-hemoglobin C disease exacerbated by sudden pain caused by sickled erythrocytes impeding blood flow within a vessel.


name: Dyskeratosis Congenita, Autosomal Dominant 3

description: Dyskeratosis congenita caused by autosomal dominant mutation(s) in the TINF2 gene, encoding TERF1-interacting nuclear factor 2. Mutations in TINF2 may also lead to another phenotype known as Revesz syndrome (Dyskeratosis Congenita, Autosomal Dominant 5).


Refractory Digestive System Carcinoma

description: A carcinoma hat arises from any part of the digestive system and is resistant to treatment.


name: Occlusion and Stenosis of Unspecified Carotid Artery

description: Evidence of occlusion and stenosis of unspecified carotid artery.


Grade 4 Diarrhea, CTCAE

description: Life-threatening consequences; urgent intervention indicated


ATRX Gene Mutation Negative

description: A genetic finding indicating that ATRX gene mutations have not been detected in a sample.


name: Hematologic Neoplasm with Germline RUNX1 Mutation

description: An autosomal dominant syndrome characterized by abnormalities in platelet number and function and enhanced risk of developing myelodysplastic syndrome/acute myeloid leukemia at a young age. Patients have germline monoallelic mutations in RUNX1 gene. The clinical presentation is variable, even within the same family. Most affected individuals have a mild to moderate bleeding tendency. Platelet counts are normal or mildly reduced, with normal platelet morphology and variable degrees of platelet dysfunction. Distinct families with germline RUNX1 mutations exhibit varying risks of development of myeloid neoplasms with 11-100% (median: 44%) of family members affected. (WHO 2017)


Parietal cell carcinoma

description: An adenocarcinoma of the stomach arising from the parietal cells. It is characterized by the presence of malignant cells with eosinophilic, finely granular cytoplasm.


name: Soft Tissue Sarcoma of the Trunk and Extremities Clinical TNM Finding v8

description: A clinical finding about one or more characteristics of soft tissue sarcoma of the trunk and extremities, following the rules of the TNM AJCC v8 classification system.


Grade 5 Hypokalemia, CTCAE

description: Death


Ischemic Change

description: Cellular damage due to diminished oxygen supply to the tissues. The changes may be mild and associated with chronic inflammation, or severe and associated with ulceration, necrosis, and hemorrhage.


name: Grade 5 Brain and Spinal Cord Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


Grade 2 Duodenal Obstruction, CTCAE

description: Symptomatic; altered GI function


Excessive Bruising

description: Bruising that is disproportionately high to the amount of trauma received or reported.


Grade 5 Leukocytosis, CTCAE

description: Death


Grade 3 Device Related Infection, CTCAE

description: IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated


name: Clinical Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8

description: Stage IV includes: IVA: (T1-4a, N2, M0); (T4b, N0-2, M0); (Any T, N3, M0); IVB: (Any T, Any N, M1). T1: Tumor invades the lamina propria, muscularis mucosae, or submucosa. T2: Tumor invades the muscularis propria. T3: Tumor invades adventitia. T4a: Tumor invades the pleura, pericardium, azygos vein, diaphragm, or peritoneum. T4b: Tumor invades other adjacent structures, such as the aorta, vertebral body, or airway. N0: No regional lymph node metastasis. N1: Tumor with metastasis in one or two regional lymph nodes. N2: Tumor with metastasis in three to six regional lymph nodes. N3: Tumor with metastasis in seven or more regional lymph nodes. M0: No distant metastasis. M1: Distant metastasis. (AJCC 8th ed.)


name: Chief Complaint is Present Multiple Times per Day

description: The chief complaint is noted to occur more than once per day.


name: Refractory Childhood Central Nervous System Neoplasm

description: A central nervous system neoplasm in childhood that is resistant to treatment.


name: diabetes mellitus type 2 with hyperglycemia

description: Evidence of type 2 diabetes mellitus with hyperglycemia.


Pancreatobiliary-type carcinoma

description: An invasive adenocarcinoma that arises from the ampulla of Vater. It is characterized by the presence of malignant cells that resemble the malignant cells of the pancreatic ductal or extrahepatic bile duct carcinomas.


name: Bile Duct Mucinous Cystic Neoplasm, High Grade

description: A non-invasive mucinous cystic neoplasm that arises from the intrahepatic or extrahepatic bile ducts.  It is characterized by the presence of severe atypia.


name: Malignant Neoplasm of Left Spermatic Cord

description: Evidence of a malignant neoplasm of the left spermatic cord.


Grade 1 Dizziness, CTCAE

description: Mild unsteadiness or sensation of movement


name: Grade 3 Oral Cavity or Gum Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


hepatoid adenocarcinoma of gallbladder

description: A rare variant of gallbladder adenocarcinoma.  It is characterized by the presence of a malignant glandular epithelial infiltrate that resembles hepatocellular carcinoma.


name: Occlusion and Stenosis of Unspecified Vertebral Artery

description: Evidence of occlusion and stenosis of unspecified vertebral artery.


Salivary Duct Inflammation, CTCAE

description: A disorder characterized by inflammation of the salivary duct.


description: Elevated bilirubin levels in the blood of a newborn infant. It is a normal response due to the limited ability to excrete bilirubin until the maturation of the neonatal liver is complete.


Testicular Cancer pN1 TNM Finding v7

description: Metastasis with a lymph node mass 2 cm or less in greatest dimension and less than or equal to five nodes positive, none more than 2 cm in greatest dimension. (from AJCC 7th Ed.)


Eyes Complete Response GvHD

description: An NIH eye score of 0 after previous GvHD involvement.


name: Type 1 Diabetes Mellitus with Moderate Nonproliferative Diabetic Retinopathy without Macular Edema

description: Evidence of type 1 diabetes mellitus with moderate nonproliferative diabetic retinopathy without macular edema.


name: Grade 2 Other Metabolic and Laboratory, CTCAE


Suboptimal Gradient Artifact

description: An artifact resulting from static and dynamic field changes in a scanner magnetic field.


name: Pre-Existing Secondary Hypertension Complicating Pregnancy, Second Trimester

description: Evidence of pre-existing secondary hypertension complicating pregnancy in the second trimester.


name: Conjunctival Carcinoma Pathologic Regional Lymph Nodes TNM Finding v8

description: A pathologic finding about one or more characteristics of conjunctival carcinoma, following the rules of the TNM AJCC v8 classification system as they pertain to staging of regional lymph nodes.


name: Grade 2 Ligament Intra-Operative Injury, CTCAE


name: Has Response to Intervention for Kawasaki Disease

description: An indication that a patient responded to a treatment for Kawasaki disease.


Colorectal Cancer pTis TNM Finding v8

description: Colorectal cancer with a finding of carcinoma in situ, intramucosal carcinoma (involvement of lamina propria with no extension through muscularis mucosae). (from AJCC 8th Ed.)


name: Carcinoma of the Eyelid Clinical Regional Lymph Nodes TNM Finding v7

description: A clinical finding about one or more characteristics of carcinoma of the eyelid, following the rules of the TNM AJCC v7 classification system as they pertain to staging of regional lymph nodes.


Abnormal Blood Protein

description: One or more of the blood protein levels being higher or lower than normal (e.g. Albumin, C-reactive Protein).


name: Type 2 Diabetes Mellitus with Hyperosmolarity without Non-Ketotic Hyperglycemic-Hyperosmolar Coma

description: Evidence of type 2 diabetes mellitus with hyperosmolarity without non-ketotic hyperglycemic-hyperosmolar coma.


name: Alcohol Use, Unspecified with Alcohol-Induced Persisting Dementia

description: Evidence of unspecified alcohol use with alcohol-induced persisting dementia.


name: Grade 4 Paranasal Infection with Unknown Absolute Neutrophil Count, CTCAE


Suboptimal Image Reason

description: An image of inferior quality, may still be adequate to make a diagnosis.


Accelerated Phase of Disease

description: The phase of a disease characterized by laboratory and clinical findings that indicate rapid progression.


name: Hypopharyngeal Cancer Clinical TNM Finding v8

description: A clinical finding about one or more characteristics of hypopharyngeal cancer, following the rules of the TNM AJCC v8 classification system.


name: Clinical Stage II Esophageal Adenocarcinoma AJCC v8

description: Stage II includes: IIA: T1, N1, M0; IIB: T2, N0, M0. T1: Tumor invades the lamina propria, muscularis mucosae, or submucosa. T2: Tumor invades the muscularis propria. N0: No regional lymph node metastasis. N1: Tumor with metastasis in one or two regional lymph nodes. M0: No distant metastasis. (AJCC 8th ed.)


Flat Affect

description: The absence of emotional expressiveness.


Non-Contiguous Disease

description: A term that usually refers to the clinical course of lymphomas and indicates that the cancerous lymph nodes are not next to each other, but are on the same side of the diaphragm.


name: Carcinoma of the Lacrimal Gland pT0 TNM Finding v7

description: Carcinoma of the lacrimal gland with no evidence of a primary tumor. (from AJCC 7th Ed.)


name: Ventilation or Perfusion Signs and Symptoms


name: Peritoneal Cavity Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


TRK Receptor Family Fusion Negative

description: Indicates that the expression of a fusion involving a TRK receptor family member has not been detected in a sample.


pM1b TNM Finding

description: A pathologic primary tumor TNM finding. The definition of PM1b TNM finding depends on the particular type of cancer that it refers to; for example, for lung cancer, PM1b TNM finding is defined as follows: cancer with single extrathoracic metastasis in a single organ (including involvement of a single nonregional node). (from AJCC 8th Ed.)


name: Intrahepatic Bile Duct Cancer TNM Finding v8

description: A finding about one or more characteristics of intrahepatic bile duct cancer, following the rules of the TNM AJCC v8 classification system. This staging system applies to intrahepatic cholangiocarcinomas, combined hepatocellular-cholangiocarcinomas (mixed hepatocholangiocarcinomas), and primary neuroendocrine tumors of the liver. Primary sarcomas of the liver, pure hepatocellular carcinomas, hilar cholangiocarcinomas, and gallbladder carcinomas are not staged using this staging system. (from AJCC 8th Ed.)


name: Grade 3 Gastrointestinal Stoma Leak, CTCAE


Grade 2 Small Intestine Ulcer, CTCAE

description: Symptomatic; altered GI function; limiting instrumental ADL


name: Grade 3 Lower Gastrointestinal Hemorrhage, CTCAE

description: Transfusion indicated; invasive intervention indicated; hospitalization


name: Grade 3 Pneumonitis and Pulmonary Infiltrates, CTCAE


name: Neuroendocrine Carcinoma of Unknown Primary

description: A neuroendocrine carcinoma that has metastasized from an  unknown primary site.


name: Preinvasive Neoplasm of the Ampullary Region

description: A premalignant neoplastic and dysplastic lesion that arises from the ampulla of Vater.  It is characterized by the absence of invasion.  This category includes intestinal-type adenomas, noninvasive papillary neoplasms of pancreatobiliary type, and flat intraepithelial neoplasia.


Anal Canal Neuroendocrine Tumor G2

description: A well differentiated, intermediate grade neoplasm with neuroendocrine differentiation that arises from the anal canal. The mitotic count is 2-20 per 10 HPF and/or the Ki67 index is 3 to 20 percent.


Normal Renal Arteriogram

description: An x-ray of the renal arteries that reveals normal results.


description: Evidence of hairy cell leukemia not having achieved remission.


Tympanogram Tracing Type

description: An interpretive summary of the tympanogram tracing result.


name: Soft Tissue Sarcoma of the Abdomen and Thoracic Visceral Organs pT3 TNM Finding v8

description: Soft tissue sarcoma of the abdomen and thoracic visceral organs with tumor invading another organ. (from AJCC 8th Ed.)


Stage IA Esophageal Cancer AJCC v7

description: Stage IA includes: For squamous cell carcinoma: T1, N0, M0, G1, GX, Tumor location: Any. T1: Tumor invades lamina propria, muscularis mucosae, or submucosa.  N0: No regional lymph node metastasis.  M0: No distant metastasis.  G1: Well differentiated.  GX: Grade cannot be assessed-stage grouping as G1.  Tumor location: Location of the primary cancer site is defined by the position of the upper (proximal) edge of the tumor in the esophagus.  For adenocarcinoma: T1, N0, M0, G1-2, X. T1: Tumor invades lamina propria, muscularis mucosae, or submucosa.  N0: No regional lymph node metastasis.  M0: No distant metastasis.  G1: Well differentiated.  G2: Moderately differentiated. GX: Grade cannot be assessed-stage grouping as G1. (AJCC 7th ed.)


name: Metastatic Digestive System Neuroendocrine Carcinoma

description: A neuroendocrine carcinoma that arises from any part of the digestive system and has metastasized to another anatomic site.


name: Grade 2 Catheter-Related Infection with Unknown Absolute Neutrophil Count, CTCAE


Grade 3 Penile Pain, CTCAE

description: Severe pain; limiting self care ADL


name: Glottic Cancer pN2c TNM Finding v6 and v7

description: Glottic cancer with metastasis in bilateral or contralateral lymph nodes, none more than 6 cm in greatest dimension. (from AJCC 6th and 7th Eds.)


name: Memory Deficit following Cerebral Infarction

description: Evidence of memory deficit following cerebral infarction.


undifferentiated carcinoma of appendix

description: A high grade carcinoma arising from the appendix, characterized by the absence of glandular or squamous differentiation.


name: Other Pre-Existing Diabetes Mellitus in Pregnancy, Third Trimester

description: Evidence of other pre-existing diabetes mellitus in pregnancy in the third trimester not specified elsewhere.


name: Nasal Cavity and Paranasal Sinuses Cancer pN0 TNM Finding v8

description: Nasal cavity and paranasal sinuses cancer with no metastasis to regional lymph nodes. (from AJCC 8th Ed.)


name: Intrahepatic Bile Duct Cancer Pathologic Distant Metastasis TNM Finding v8

description: A pathologic finding about one or more characteristics of intrahepatic bile duct cancer, following the rules of the TNM AJCC v8 classification system as they pertain to distant metastases.


name: Ocular Adnexal Lymphoma Clinical TNM Finding v8

description: A clinical finding about one or more characteristics of ocular adnexal lymphoma, following the rules of the TNM AJCC v8 classification system.


name: Grade 5 Peripheral Nerve Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


Grade 5 Aortic Valve Disease, CTCAE

description: Death


name: Antimicrobial Dose Dependent Susceptibility Result

description: A microbial susceptibility test result in which the growth of microorganisms may be inhibited when higher than normal dosages of an antimicrobial agent are used and maximal possible blood concentration of the antimicrobial agent is achieved.


name: Grade 1 Cranial Nerve XI Neuropathy, CTCAE


Childhood Esophageal Carcinoma

description: A rare carcinoma of the esophagus that occurs during childhood.


name: Pancreatic Neuroendocrine Tumor Pathologic TNM Finding v8

description: A pathologic finding about one or more characteristics of a pancreatic neuroendocrine tumor, following the rules of the TNM AJCC v8 classification system.


name: Localized Malignant Supratentorial Neoplasm

description: A malignant supratentorial neoplasm that is confined to a specific site without evidence of spread to other anatomic sites.


Prostate Imaging Area

description: The region(s) of the prostate being visualized through one or more radiologic techniques, including ultrasound (U/S), computed tomography (CT), and magnetic resonance imaging (MRI).


name: Grade 2 Lens Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


name: Grade 5 Pregnancy, Puerperium and Perinatal Conditions - Other, Specify, CTCAE

description: Death


Hereditary Lesion

description: A pathologic process inherited in a familial pattern.


name: Jejunum and Ileum Neuroendocrine Tumor Pathologic Distant Metastasis TNM Finding v8

description: A pathologic finding about one or more characteristics of a jejunum and ileum neuroendocrine tumor, following the rules of the TNM AJCC v8 classification system as they pertain to distant metastases.


Grade 1 Fever, CTCAE

description: 38.0-39.0 degrees C (100.4-102.2 degrees F)


Distal Urethral Carcinoma

description: A carcinoma that arises from the distal part of the urethra.


Grade 1 Pharyngeal Stenosis, CTCAE

description: Asymptomatic; clinical or diagnostic observations only; intervention not indicated


Tuberculosis of adrenal glands

description: Tuberculosis of the adrenal gland.


name: Type 2 Diabetes Mellitus with Moderate Nonproliferative Diabetic Retinopathy with Macular Edema, Unspecified Eye

description: Evidence of type 2 diabetes mellitus with moderate nonproliferative diabetic retinopathy with macular edema in an unspecified eye.


name: Cutaneous Squamous Cell Carcinoma of the Head and Neck pT2 TNM Finding v8

description: Cutaneous squamous cell carcinoma of the head and neck with tumor 2 cm or larger, but smaller than 4 cm in greatest dimension. (from AJCC 8th Ed.)


Breast Cancer pN0 TNM Finding v8

description: Breast cancer in which no regional lymph node metastasis is identified or isolated tumor cell clusters (ITCs) are identified only. (from AJCC 8th Ed.)


name: Upper Aerodigestive NOS Intra-Operative Injury, CTCAE


Grade 5 Ileus, CTCAE

description: Death


name: Grade 3 Small Bowel NOS Intra-Operative Injury, CTCAE


name: Grade 4 Right Ventricular Dysfunction, CTCAE

description: Life-threatening consequences; urgent intervention indicated (e.g., ventricular assist device); heart transplant indicated


name: Grade 4 Biliary Tree Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


name: Testicular Sex Cord-Gonadal Stromal Tumor, Mixed Forms

description: A sex cord-stromal tumor of the testis which may contain any combination of cell types, for example Sertoli cells, Leydig cells, and granulosa cells. Symptoms include testicular swelling and gynecomastia.


name: Lugano Classification Stage II Bulky Adult Lymphoma AJCC v8

description: Stage II Bulky: Stage II with disease bulk. (from AJCC 8th Ed.)


name: Grade 2 CD4 Lymphocytes Decreased, CTCAE

description: <500-200/mm3; <0.5-0.2 x 10e9/L


Schizoaffective disorder, bipolar type

description: Schizoaffective disorder with episodes of mania and depression.


name: Grade 5 Lower Extremity Artery Injury, CTCAE


Reiter's Disease, Right Wrist

description: Evidence of Reiter's disease in the right wrist.


Grade 5 Ileal Stenosis, CTCAE

description: Death


Grade 5 Enterovesical Fistula, CTCAE

description: Death


name: Digestive System Large Cell Neuroendocrine Carcinoma

description: An aggressive, high-grade and poorly differentiated carcinoma with neuroendocrine differentiation that arises from any part of the gastrointestinal system.  It is characterized by the presence of malignant large cells.


name: Drug or Chemical Induced Diabetes Mellitus with Other Skin Complications

description: Evidence of drug or chemical induced diabetes mellitus with other skin complications.


Grade 3 Flu Like Symptoms, CTCAE

description: Severe symptoms; limiting self care ADL


name: Cutaneous Squamous Cell Carcinoma of the Head and Neck pN3 TNM Finding v8

description: Cutaneous squamous cell carcinoma of the head and neck with metastasis in a lymph node larger than 6 cm in greatest dimension and ENE(-); or metastasis in a single ipsilateral lymph node larger than 3 cm in greatest dimension and ENE(+); or metastases in multiple ipsilateral, contralateral, or bilateral lymph nodes, any with ENE(+). (from AJCC 8th Ed.)


name: Clinical Stage IV Cutaneous Melanoma AJCC v8

description: Stage IV includes: Any T, Any N, M1. M1: Evidence of distant metastasis. (AJCC 8th ed.)


name: Grade 2 Muscle Weakness Left-Sided, CTCAE

description: Symptomatic; evident on physical exam; limiting instrumental ADL


Sustained Virologic Response

description: A finding of aviremia at a predetermined time point after the end of planned or actual treatment.


Gastrointestinal Carcinoid Tumor

description: A well differentiated neuroendocrine neoplasm of low grade arising from the digestive system. It is composed of islands of rounded, oxyphilic, or spindle-shaped cells of medium size, with small vesicular nuclei. The mitotic count is less than 2 per 10 HPF and/or the Ki67 index is equal to or less than 2 percent. The tumor can occur anywhere in the digestive system; approximately 90% arise in the appendix.


Grade 4 Chylous Ascites, CTCAE

description: Life-threatening consequences; urgent operative intervention indicated


name: PSA Level Greater than or Equal to Fifty

description: A blood concentration of prostate specific antigen greater than or equal to 50 ng/mL.


Iris Melanoma pT2a TNM Finding v8

description: Iris melanoma with tumor confluent with or extending into the ciliary body, without secondary glaucoma. (from AJCC 8th Ed.)


name: Unspecified B-Cell Lymphoma, Lymph Nodes of Inguinal Region and Lower Limb

description: Evidence of unspecified B-cell lymphoma in the lymph nodes of inguinal region and lower limb.


Refractory Esophageal Adenocarcinoma

description: Esophageal adenocarcinoma that is resistant to treatment.


name: Small Bowel Stricture or Stenosis NOS, CTCAE


name: Atherosclerosis of Unspecified Type of Bypass Graft(s) of the Extremities with Intermittent Claudication, Bilateral Legs

description: Evidence of atherosclerosis of unspecified type of bypass graft(s) of the extremities with intermittent claudication in both legs.


name: Glottic Cancer Pathologic Distant Metastasis TNM Finding v6

description: A pathologic finding about one or more characteristics of glottic cancer, following the rules of the TNM classification system as they pertain to distant metastases.


HLA-C Match Finding

description: The extent of HLA-C matching between the donor and the recipient.


name: Stage II Adult Diffuse Mixed Cell Lymphoma

description: Stage II: Involvement of two or more lymph node regions on the same side of the diaphragm (II) or localized involvement of a single associated extralymphatic organ or site and its regional lymph nodes with or without other lymph node regions on the same side of the diaphragm (IIE). Note: The number of lymph node regions involved may be indicated by a subscript (e.g., II3). (from PDQ)


Neonatal Pneumothorax, AE

description: An adverse event in a newborn characterized by a collection of air or other gas between the visceral and parietal pleura.


name: Grade 3 Upper Airway Infection NOS with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


name: Unspecified inflammatory spondylopathy, lumbar region

description: Evidence of unspecified inflammatory spondylopathy in the lumbar region.


Minimal Disseminated Disease

description: A clinical finding that refers to the spread of a neoplastic disease to anatomic sites or systems other than the original neoplastic site through the detection of low or subclinical levels of a neoplastic marker.


name: Pauciarticular Juvenile Rheumatoid Arthritis, Left Wrist

description: Evidence of pauciarticular juvenile rheumatoid arthritis in the left wrist.


Cervical Cancer cT1b2 TNM Finding v8

description: Cervical cancer with clinically visible lesion more than 4.0 cm in greatest dimension. (from AJCC 8th Ed.)


name: Juvenile Arthritis, Unspecified, Unspecified Ankle and Foot

description: Evidence of unspecified juvenile arthritis in the ankle and foot.


name: Malignant neoplasm of upper respiratory tract

description: Evidence of a malignant neoplasm of the upper respiratory tract, part unspecified.


Chemical Gastritis

description: Gastritis caused by injury to the gastric mucosa by chemicals. The injury occurs due to reflux of bile and pancreatic enzymes.


name: Hemiplegia, Unspecified Affecting Left Non-Dominant Side

description: Evidence of hemiplegia, unspecified affecting left non-dominant side.


name: Upper Extremity Soft Tissue Necrosis, CTCAE


name: Embolism and thrombosis of arteries of extremities, unspecified

description: Evidence of embolism and thrombosis of arteries of extremities.


Grade 1 Ileus, CTCAE

description: Asymptomatic and radiologic observations only


name: Grade 2 Middle Ear Intra-Operative Injury, CTCAE


name: Grade 2 Metabolism and Nutrition Disorders - Other, Specify, CTCAE

description: Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL


name: Grade 4 Kidney Infection with Unknown Absolute Neutrophil Count, CTCAE


name: Grade 2 Middle Ear Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


HLA Match Finding

description: A process in which blood or tissue samples are analyzed to determine their human leukocyte antigen (HLA) profiles so that transplant materials can be transferred into a patient with the same or similar profile.


name: Nasopharynx Intra-Operative Injury, CTCAE


name: Diffuse malignant lymphoma - centroblastic-centrocytic


Stage IIB Gastric Cancer AJCC v7

description: Stage IIB includes: (T4a, N0, M0); (T3, N1, M0); (T2, N2, M0); (T1, N3, M0).  T1: Tumor invades lamina propria, muscularis mucosae, or submucosa.  T2: Tumor invades the muscularis propria. T3: Tumor penetrates subserosal connective tissue without invasion of visceral peritoneum or adjacent structures.  T4a: Tumor invades serosa (visceral peritoneum).  N0: No regional lymph node metastasis.  N1: Metastasis in 1-2 regional lymph nodes.  N2: Metastasis in 3-6 regional lymph nodes.  N3: Metastasis in seven or more regional lymph nodes.  M0: No distant metastasis. (AJCC 7th ed.)


name: Childhood Ependymoma by Toronto Guidelines v2 Stage

description: A term that refers to the staging of childhood ependymoma according to the Toronto childhood cancer staging guidelines v2.


Atrophic arthritis

description: An antiquated term indicating arthritis and bone loss.


name: Pleural Mesothelioma Pathologic TNM Finding v7

description: A pathologic finding about one or more characteristics of pleural mesothelioma, following the rules of the TNM AJCC v7 classification system.  The pathologic staging is based on surgical resection. (from AJCC 7th Ed.)


name: Grade 2 Vagina Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


name: Grade 3 Intraoperative Ocular Injury, CTCAE

description: Complete resection or reconstruction of injured organ/structure indicated; limiting self care ADL


Reiter's Disease, Unspecified Shoulder

description: Evidence of Reiter's disease in an unspecified shoulder.


Grade 5 Neonatal Sinus Tachycardia, AE

description: A sinus tachycardia adverse event in a newborn which results in death.


name: Grade 5 Small Bowel Obstruction NOS, CTCAE


name: Other Inflammatory Spondylopathies, Thoracic Region

description: Evidence of other inflammatory spondylopathies in the thoracic region not specified elsewhere.


name: Grade 4 Recurrent Laryngeal Nerve Intra-Operative Injury, CTCAE


Carcinoma in situ of fallopian tube

description: Stage 0 includes: Tis, N0, M0.  Tis: Carcinoma in situ (limited to tubal mucosa). N0: No regional lymph node metastasis.  M0: No distant metastasis. FIGO no longer includes stage 0. (AJCC 7th ed.)


name: Dermatopolymyositis, Unspecified with Myopathy

description: Evidence of dermatopolymyositis, unspecified with myopathy.


name: Grade 4 Pancreas Intra-Operative Injury, CTCAE


name: malignant neoplasm of skin of right upper eyelid, including canthus

description: Evidence of unspecified malignant neoplasm of the skin of the right upper eyelid including the canthus.


Grade 1 Arachnoiditis, CTCAE

description: Mild symptoms


name: Rheumatoid Heart Disease with Rheumatoid Arthritis of Unspecified Shoulder

description: Evidence of rheumatoid heart disease with rheumatoid arthritis of unspecified shoulder.


Lower GI Complete Response GvHD

description: An NIH lower GI score of 0 after previous GvHD involvement.


Cytogenetic Abnormalities Present

description: A finding indicating the presence of cytogenetic abnormalities in a sample.


name: Grade 4 Small Intestinal Obstruction, CTCAE

description: Life-threatening consequences; urgent operative intervention indicated


name: Mycosis Fungoides and Sezary Syndrome NX TNM Finding v8

description: Clinically abnormal peripheral lymph nodes; no histologic confirmation. (from AJCC 8th Ed.)


name: Grade 5 Kidney Infection with Unknown Absolute Neutrophil Count, CTCAE


name: MITF Pathway-Activated Melanocytic Tumor

description: A cutaneous neoplasm associated with MITF gene rearrangement and either ACTIN-MITF translocation or MITF-CREM translocation. It is composed of large cells with clear cytoplasm that exhibit melanocytic differentiation and proliferate in the dermis. It presents as a single non-pigmented cutaneous nodule.


Grade 3 Anal Mucositis, CTCAE

description: Severe symptoms; limiting self care ADL


small cell carcinoma of appendix

description: An aggressive, high-grade, and poorly differentiated carcinoma with neuroendocrine differentiation that arises from the wall of the appendix. It is characterized by the presence of malignant small cells.


name: Adverse Event Associated with the Musculoskeletal System and Soft Tissue


name: Merkel Cell Carcinoma cT3 TNM Finding v8

description: Merkel cell carcinoma with maximum clinical tumor diameter more than 5 cm. (from AJCC 8th Ed.)


Acute and chronic inflammation

description: The coexistence of a chronic inflammatory process with a superimposed polymorphonuclear neutrophilic infiltration.


name: Grade 2 Neuroendocrine Gonadotropin Secretion Abnormality, CTCAE


name: Childhood Pre-B Acute Lymphoblastic Leukemia

description: Pre-B acute lymphoblastic leukemia that occurs during childhood.


name: Rheumatoid Polyneuropathy with Rheumatoid Arthritis of Unspecified Ankle and Foot

description: Evidence of rheumatoid polyneuropathy with rheumatoid arthritis of unspecified ankle and foot.


Grade 4 Epistaxis, CTCAE

description: Life-threatening consequences; urgent intervention indicated


name: Type 2 Diabetes Mellitus with Proliferative Diabetic Retinopathy with Combined Traction Retinal Detachment and Rhegmatogenous Retinal Detachment, Bilateral

description: Evidence of type 2 diabetes mellitus with proliferative diabetic retinopathy with combined traction retinal detachment and rhegmatogenous retinal detachment that is bilateral.


Sinus Pain

description: Painful sensation in the face, between the eyes, or upper teeth originating from the sinuses. It is usually caused by sinus infections.


Moderate Protein-Calorie Malnutrition

description: Evidence of moderate protein-calorie malnutrition.


name: Duodenal ulcer, chronic or unspecified with both hemorrhage and perforation

description: Evidence of chronic or unspecified duodenal ulcer with both hemorrhage and perforation.


In situ follicular neoplasia

description: A follicular neoplasia confined to the germinal centers of the lymph nodes, without evidence of disseminated disease. It is characterized by the replacement of a germinal center by neoplastic centrocytes with uniformly intense positivity for BCL2. The surrounding mantle cuff and lymphoid architecture are intact. It has a low rate of progression to follicular lymphoma, but is often associated with prior or synchronous overt lymphoma.


Benign Familial Infantile Seizures

description: A genetically heterogenous afebrile seizure disorder of infancy, typically occurring between the third and eight month of life, that is characterized by brief partial seizures occurring in clusters over a day or several days. Psychomotor and neurologic development before and after seizures are normal.


name: Greater than Minimal Area of Interest on Radiograph

description: A radiographic finding of areas of interest greater than the minimal.


name: Grade 4 Local Complication of Device and Prosthesis, CTCAE


name: Refractory Anal Canal Squamous Cell Carcinoma

description: Anal canal squamous cell carcinoma that is resistant to treatment.


Chronic candidiasis

description: Candidiasis that is persistent or long-standing in nature.


name: Grade 1 Retroperitoneum Hemorrhage, CTCAE


Clear cell adenocarcinoma of lung

description: A well differentiated morphologic variant of lung adenocarcinoma characterized by the predominance of clear cells.


Grade 1 Flushing, CTCAE

description: Asymptomatic; clinical or diagnostic observations only


name: Foreign Body Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


name: Benign Germinative Follicular Epithelium Neoplasm

description: A neoplasm that arises from the germinative follicular epithelium and is characterized by the absence of atypical or malignant cytological and architectural features, and absence of invasive features or metastatic potential.


Bladder Cancer pN0 TNM Finding v8

description: Bladder cancer with no lymph node metastasis. (from AJCC 8th Ed.)


name: Primary Cutaneous B-Cell/T-Cell (Non-MF/SS) Lymphoma T1 TNM Finding v8

description: Solitary skin involvement. (from AJCC 8th Ed.)


Grade 3 Wrist Fracture, CTCAE

description: Limiting self care ADL; elective operative intervention indicated requiring hospitalization


name: Benign neoplasm of extrahepatic bile ducts

description: A neoplasm that arises from the extrahepatic bile ducts and is characterized by the absence of atypical or malignant cytological and architectural features, and absence of invasive features or metastatic potential.


Resectable Oligodendroglioma

description: An oligodendroglioma that is amenable to surgical resection.


name: Distal Bile Duct Cancer Pathologic Regional Lymph Nodes TNM Finding v7

description: A pathologic finding about one or more characteristics of distal bile duct cancer, following the rules of the TNM AJCC v7 classification system as they pertain to staging of regional lymph nodes.


name: Localized Gastroesophageal Junction Adenocarcinoma

description: An adenocarcinoma that arises from the gastroesophageal junction and has not spread to other anatomic sites.


Cervical Cancer cT2 TNM Finding v7

description: Cervical cancer invades beyond uterus but not to pelvic wall or to lower third of vagina. (from AJCC 7th Ed.)


name: Diabetes Mellitus due to Underlying Condition with Severe Non-Proliferative Diabetic Retinopathy without Macular Edema, Left Eye

description: Evidence of diabetes mellitus due to underlying condition with severe non-proliferative diabetic retinopathy without macular edema in the left eye.


name: partial retinal artery occlusion of both eyes

description: Evidence of partial retinal artery occlusion that is bilateral.


Congenital non-progressive ataxia

description: A clinically and genetically heterogenous group of rare, predominantly non-progressive neurological disorders present at birth and characterized by hypotonia, developmental delays, and ataxia. Cognitive and motor impairments may improve over time.


Cervical Non-Neoplastic Disorder

description: A non-neoplastic disorder that affects the cervix. Representative examples include endometriosis and cervicitis.


name: Malignant Lymphoma, Non-Cleaved Cell Type


Stage II Vulvar Cancer AJCC v7

description: Stage II includes: T2, N0, M0.  T2: Vulvar cancer with tumor of any size with extension to adjacent perineal structures (lower/distal 1/3 urethra, lower/distal 1/3 vagina, anal involvement).  N0: No regional lymph node metastasis.  M0: No distant metastasis.  (AJCC 7th ed.)


name: Carcinoma Arising in Bladder Diverticulum

description: A carcinoma arising in a bladder diverticulum. Approximately one-third to half of the cases represent non-invasive, low-grade or high-grade urothelial carcinomas. Approximately half of the invasive carcinomas are urothelial. The rest include adenocarcinomas, squamous cell carcinomas, and small cell carcinomas.


Grade 2 Nail Infection, CTCAE

description: Oral intervention indicated (e.g., antibiotic, antifungal, or antiviral)


name: Carcinoma in Situ of Skin of Right Lower Limb, Including Hip

description: Evidence of carcinoma in situ of the skin of right lower limb including the hip.


Gastric Cancer pT2 TNM Finding v6

description: Gastric cancer with tumor invading the muscularis propria or subserosa. A tumor may penetrate the muscularis propria with extension into the gastrocolic or gastrohepatic ligaments, or into the greater or lesser omentum, without perforation of the visceral peritoneum covering these structures. In this case, the tumor is classified T2. If there is perforation of the visceral peritoneum covering the gastric ligaments or the omentum, the tumor should be classified T3. (from AJCC 6th Ed.)


name: Grade 3 Blood Bilirubin Increased, CTCAE

description: >3.0-10.0 x ULN if baseline was normal; >3.0-10.0 x baseline if baseline was abnormal


Grade 5 Gallbladder Infection, CTCAE

description: Death


Grade 5 Typhlitis, CTCAE

description: Death


Grade 1 Diffuse Follicular Lymphoma

description: A follicular lymphoma with diffuse pattern characterized by the presence of 5 or less centroblasts per 40 high-power fields.


name: Maxillary Sinus Cancer pN2c TNM Finding v6 and v7

description: Maxillary sinus cancer with metastasis in bilateral or contralateral lymph nodes, none more than 6 cm in greatest dimension. (from AJCC 6th and 7th Eds.)


Decreased Bone Density

description: A laboratory finding indicating the presence of lower than normal bone mineral density.


PSA Level Greater than Fifty

description: A blood concentration of prostate specific antigen above 50 ng/mL.


name: Stage IV Low Grade Adult Non-Hodgkin's Lymphoma


Unresectable Osteosarcoma

description: An osteosarcoma which is not amenable to surgical resection.


Multiple Metastases

description: More than one metastatic area.


Device Complication

description: Any problem arising from the use of a medical device.


Infusion Site Extravasation, CTCAE

description: A disorder characterized by leakage of the infusion into the surrounding tissue. Signs and symptoms may include induration, erythema, swelling, burning sensation and marked discomfort at the infusion site.


name: Maxillary Sinus Cancer pTX TNM Finding v8

description: Maxillary sinus cancer in which the primary tumor cannot be assessed. (from AJCC 8th Ed.)


Grade 3 Purpura, CTCAE

description: Combined area of lesions covering >30% BSA; spontaneous bleeding


name: Cervical Lymph Nodes and Unknown Primary Tumors TNM Finding v8

description: A finding about one or more characteristics of cervical lymph nodes and unknown primary tumors, following the rules of the TNM AJCC v8 classification system. It applies to squamous cell carcinoma and salivary gland carcinoma of all head and neck sites except HPV-related oropharynx cancer, nasopharynx cancer, melanoma, thyroid carcinoma, and sarcoma. Staging of the patient who presents with an occult primary tumor and EBV-unrelated and HPV-unrelated metastatic cervical lymphadenopathy is also included. (from AJCC 8th Ed.)


name: Maxillary Sinus Cancer cM0 TNM Finding v7

description: Maxillary sinus cancer without evidence of distant metastasis. (from AJCC 7th Ed.)


Decreased Concomitant Drug AUC

description: Decreased area under the plot of plasma concentration of a concomitant drug against time after its administration.


Giant cell and spindle cell carcinoma

description: A malignant epithelial neoplasm composed of giant, pleomorphic cells and spindle cells.


Neonatal Edema, AE

description: An adverse event in a newborn characterized by accumulation of an excessive amount of fluid in cells or intercellular tissues.


name: Grade 1 Oculomotor Nerve Disorder, CTCAE

description: Asymptomatic; clinical or diagnostic observations only; intervention not indicated


name: Gallbladder Benign Non-Epithelial Neoplasm

description: A non-epithelial neoplasm that arises from the gallbladder and is characterized by the absence of atypical or malignant cytological and architectural features, and absence of invasive features or metastatic potential. Representative examples include leiomyoma, lipoma, and neurofibroma.


Lung Cancer pN1 TNM Finding

description: Lung cancer with metastasis to ipsilateral peribronchial and/or ipsilateral hilar lymph nodes, including intrapulmonary nodes involved by direct extension of the primary tumor. (from CAP Lung Cancer Protocol--January 2005 Revision)


name: Borderline Fallopian Tube Endometrioid Tumor

description: A neoplasm of low malignant potential arising from the fallopian tube. It is characterized by the presence of glandular or cystic spaces which contain atypical glandular epithelial cells resembling endometrial cells.  There is no evidence of stromal invasion.


name: Grade 1 Anal Sphincter Intra-Operative Injury, CTCAE


name: Maxillary Sinus Cancer Pathologic Regional Lymph Nodes TNM Finding v7

description: A pathologic finding about one or more characteristics of maxillary sinus cancer, following the rules of the TNM AJCC v7 classification system as they pertain to staging of regional lymph nodes.


name: Non-T Non-B CALLA Positive Adult Acute Lymphoblastic Leukemia

description: A non-T, non-B, acute lymphoblastic leukemia in which the lymphoblasts are positive for the common acute lymphoblastic leukemia antigen (CALLA) occurring in adults.


name: Appendicular Skeleton, Trunk, Skull, and Facial Bones Cancer pT3 TNM Finding v8

description: Appendicular skeleton, trunk, skull, and facial bones cancer with discontinuous tumors in the primary bone site. (from AJCC 8th Ed.)


name: Pathologic Stage IIA Merkel Cell Carcinoma AJCC v8

description: Stage IIA includes: T2-3, N0, M0. T2: Maximum clinical tumor diameter more than 2 cm but equal to or less than 5 cm. T3: Maximum clinical tumor diameter more than 5 cm. N0: No regional lymph node metastasis detected on pathologic examination. M0: No distant metastasis detected on clinical and/or radiologic examination. (AJCC 8th ed.)


Non-rheumatic mitral valve prolapse

description: Evidence of non-rheumatic mitral valve prolapse.


Circumferential Margin Status by MRI

description: The determination by MRI of the presence or absence of neoplastic tissue outside of a circumferential resection margin.


name: Other Specified Diabetes Mellitus with Moderate Nonproliferative Diabetic Retinopathy without Macular Edema, Left Eye

description: Evidence of other specified diabetes mellitus with moderate nonproliferative diabetic retinopathy without macular edema in the left eye not specified elsewhere.


Grade 5 Colonic Ulcer, CTCAE

description: Death


Grade 4 Peritoneal Necrosis, CTCAE

description: Life-threatening consequences; urgent operative intervention indicated


Lung Cancer cM1b TNM Finding v7

description: Distant metastasis. (from AJCC 7th Ed.)


name: Grade 2 Brain Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


name: Grade 2 Salivary Gland Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


pTis TNM Finding

description: A term that refers to a TNM finding of a primary tumor microscopically defined as carcinoma in situ.


Non-Neoplastic Corneal Disorder

description: A non-neoplastic disorder that affects the cornea.


name: Hodgkin's disease mixed cellularity stage I site unspecified

description: Ann Arbor Classification: Stage I: Involvement of a single lymph node region (I); or localized involvement of a single extralymphatic organ or site in the absence of any lymph node involvement (IE) (rare in Hodgkin lymphoma).


name: Cannabis Abuse with Unspecified Cannabis-Induced Disorder

description: Evidence of cannabis abuse with unspecified cannabis-induced disorder.


Grade 2 Folliculitis, CTCAE

description: Covering 10-30% of the body surface area; topical intervention initiated


name: Vaginal Cancer Pathologic TNM Finding v7

description: A pathologic finding about one or more characteristics of vaginal cancer, following the rules of the TNM AJCC v7 classification system.


Vulvar Warty Carcinoma

description: A squamous cell carcinoma that arises from the vulva and is characterized by the presence of a warty surface and cellular changes that are caused by human papillomavirus infection.


name: Appendix Enterochromaffin Cell Serotonin-Producing Neuroendocrine Tumor

description: A well differentiated neuroendocrine tumor arising from the wall of the appendix.  It is characterized by the presence of neoplastic cells forming round solid nests and occasionally glandular structures.  The majority of the cases are asymptomatic, and they are found incidentally in appendectomy specimens.  The majority of the tumors are located in the distal end of the appendix and they are enterochromaffin-cell carcinoid tumors producing serotonin.  Most cases show morphologic evidence of appendiceal wall and lymphatic vessel invasion by tumor cells.  Despite the morphologic evidence of invasion, appendiceal carcinoid tumors only infrequently produce lymph node or distant metastases.


name: Peptic Ulcer, Site Unspecified, Unspecified as Acute or Chronic, without Hemorrhage or Perforation

description: Evidence of peptic ulcer, site unspecified, unspecified as acute or chronic, without hemorrhage or perforation.


Activating EGFR Gene Mutation Negative

description: A genetic finding indicating that mutations in the EGFR gene which encode constitutively active forms of the epidermal growth factor receptor protein are not present in a sample.


name: Major Salivary Gland Cancer pN3b TNM Finding v8

description: Major salivary gland cancer with metastasis in a single ipsilateral node larger than 3 cm in greatest dimension and ENE(+); or multiple ipsilateral, contralateral, or bilateral nodes any with ENE(+). (from AJCC 8th Ed.)


Solid Neoplasm

description: A benign or malignant neoplasm arising from tissues that do not include fluid areas.  Representative examples include epithelial neoplasms (e.g. lung carcinoma, prostate carcinoma, breast carcinoma, colon carcinoma), and neoplasms arising from the soft tissues and bones (e.g. leiomyosarcoma, liposarcoma, chondrosarcoma, osteosarcoma).  Neoplasms originating from the blood or bone marrow (leukemias and myeloproliferative disorders) are not considered solid tumors.


name: Grade 3 Large Intestinal Anastomotic Leak, CTCAE

description: Severe symptoms; invasive intervention indicated


Laboratory Test Result

description: The outcome of a laboratory test.


9/10 HLA Match

description: Degree of HLA match is 9/10 for HLA-A, -B, -C, -DRB1, and -DQB1 loci.


name: Soft Tissue Sarcoma of the Trunk and Extremities pT2 TNM Finding v8

description: Soft tissue sarcoma of the trunk and extremities with tumor measuring more than 5 cm and less than or equal to 10 cm in greatest dimension. (from AJCC 8th Ed.)


name: Grade 3 Other Dermatology or Skin, CTCAE


Cutaneous Melanoma pT1a TNM Finding v7

description: Cutaneous melanoma with a tumor measuring 1.0 mm or less in thickness, without ulceration and with mitosis less than 1/mm2. (from AJCC 7th Ed.)


name: Atherosclerosis of Other Type of Bypass Graft(s) of the Extremities with Gangrene, Right Leg

description: Evidence of atherosclerosis of other type of bypass graft(s) of the extremities with gangrene in the right leg.


Intimal dissection

description: A dissection of an artery that occurs though a tear in the inner lining of the blood vessel.


Grade 3 Laryngospasm, CTCAE

description: Recurrent episodes; noninvasive intervention indicated (e.g., breathing technique, pressure point massage)


Advanced Pancreatobiliary Carcinoma

description: A carcinoma that arises from the pancreas, bile ducts, gallbladder, or ampulla of Vater and has spread extensively to other anatomic sites or is no longer responding to treatment.


name: Testicular Yolk Sac Tumor, Postpubertal-Type

description: Testicular yolk sac tumor that is associated with germ cell neoplasia in situ and usually occurs as a component of mixed germ cell tumor. Pure postpubertal-type testicular yolk sac tumor is exceedingly rare.


Grade 4 Uterine Fistula, CTCAE

description: Life-threatening consequences; urgent intervention indicated


name: Grade 2 Stenosis of Gastrointestinal Stoma, CTCAE

description: Symptomatic; IV fluids indicated <24 hrs; manual dilation at bedside


name: Gastric ulcer, chronic or unspecified with perforation

description: Evidence of chronic or unspecified gastric ulcer with perforation.


Gallbladder Obstruction, CTCAE

description: A disorder characterized by blockage of the normal flow of the contents of the gallbladder.


Paratesticular Mesothelial Neoplasm

description: A mesothelial neoplasm that arises from the paratesticular structures. It includes adenomatoid tumor, well differentiated papillary mesothelial tumor, and malignant mesothelioma.


Urethra Obstruction, CTCAE

description: Blockage of the normal flow of urine in the urethra occurring following a procedure or pharmaceutical intervention.


Other cerebral palsy

description: Evidence of other cerebral palsy not specified elsewhere.


Tissue Kallikrein Deficiency

description: A disorder characterized by the partial or complete absence of tissue-type kallikrein activity in the tissues and glandular secretions where it is normally present.


name: Carcinoma in Situ of Other Urinary Organs

description: Evidence of carcinoma in situ of other urinary organs.


Cutaneous Melanoma by AJCC v6 Stage

description: A term that refers to the staging of cutaneous melanoma, following the rules of the TNM AJCC v6 classification system.


Nasopharyngeal Cancer TNM Finding v6

description: A finding about one or more characteristics of nasopharyngeal cancer, following the rules of the TNM AJCC v6 classification system.


Normal Laboratory Test Result

description: A laboratory test result indicating the results of the lab test are within normal parameters for the age and population.


Alpha trait thalassemia

description: A condition in which a person has reduced protein production from two of the four alpha-globin alleles.


Fatigue, CTCAE 5.0

description: A disorder characterized by a state of generalized weakness with a pronounced inability to summon sufficient energy to accomplish daily activities.


name: Malignant Neoplasm of Peripheral Nerves of Right Lower Limb, Including Hip

description: Evidence of a malignant neoplasm of the peripheral nerves of right lower limb including the hip.


name: Grade 5 Peritoneal Cavity Infection with Unknown Absolute Neutrophil Count, CTCAE


Needle injury

description: A penetrating stab wound from a needle (or other sharp object) that may result in exposure to blood or other body fluids.


name: Grade 2 Lower Extremity Artery Intra-Operative Injury, CTCAE


name: Monoplegia of Upper Limb following Unspecified Cerebrovascular Disease Affecting Left Non-Dominant Side

description: Evidence of monoplegia of upper limb following unspecified cerebrovascular disease affecting left non-dominant side.


name: Toxic liver disease with other disorders of liver

description: Evidence of toxic liver disease with other disorders of liver.


name: Glandular Cell Intraepithelial Neoplasia


Lymphedema, CTCAE

description: A disorder characterized by excessive fluid collection in tissues that causes swelling.


Virus-Related Lymphoma

description: Lymphoma that is caused by a virus infection.


name: Grade 2 Wound Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


name: Grade 5 Intraoperative Respiratory Injury, CTCAE

description: Death


Grade 1 Watering Eyes, CTCAE

description: Intervention not indicated


Grade 5 Psychosis, CTCAE

description: Death


name: Throat and Pharynx and Larynx Pain, CTCAE


Atypical hyperplasia of breast

description: A general term that refers to atypical hyperplastic proliferations of the epithelial cells in the breast parenchyma.  Examples include atypical ductal hyperplasia, atypical lobular hyperplasia, and columnar cell hyperplasia with atypia.


Symptomatic Deterioration

description: A global deterioration of health status providing evidence of disease progression not covered by disease response criteria (eg. RECIST).


Grade 5 Rash Acneiform, CTCAE

description: Death


name: Supraglottic Cancer Pathologic Primary Tumor TNM Finding v7

description: A pathologic finding about one or more characteristics of supraglottic cancer, following the rules of the TNM AJCC v7 classification system as they pertain to staging of the primary tumor.


name: Grade 3 Spleen Intra-Operative Injury, CTCAE


name: Endocrine mucin-producing sweat gland carcinoma

description: A rare, low-grade sweat gland carcinoma with neuroendocrine differentiation. It usually arises on the eyelids and periorbital skin. It affects mostly older individuals. Women are affected more frequently than men. Morphologically, it is characterized by well-demarcated nodules with cystic, papillary, or cribriform architectural patterns. The neoplastic cells are small to intermediate polygonal to round cells. Small amounts of intracellular or extracellular mucin are present. In some cases, this carcinoma is a precursor of mucinous carcinoma.


name: Adrenal Cortical Carcinoma Pathologic TNM Finding v8

description: A pathologic finding about one or more characteristics of adrenal cortical carcinoma, following the rules of the TNM AJCC v8 classification system.


Refractory Non-Cutaneous Melanoma

description: Non-cutaneous melanoma that is resistant to treatment.


Intracranial Leptomeningeal Lesion

description: A non-neoplastic or neoplastic pathologic process affecting the leptomeninges of the brain.


name: Duodenum and Ampulla of Vater Neuroendocrine Tumor Pathologic Distant Metastasis TNM Finding v8

description: A pathologic finding about one or more characteristics of a duodenum and ampulla of Vater neuroendocrine tumor, following the rules of the TNM AJCC v8 classification system as they pertain to distant metastases.


Testicular Cancer cN1 TNM Finding v7

description: Metastasis with a lymph node mass 2 cm or less in greatest dimension; or multiple lymph nodes, none more than 2 cm in greatest dimension. (from AJCC 7th Ed.)


Acquired Absence of Organ

description: The absence of an organ, the cause of which is not present at birth.


pN1a TNM Finding

description: A pathologic regional lymph node TNM finding. The definition of pN1a finding depends on the particular type of cancer that it refers to; for example, for breast cancer, pN1a finding is defined as follows: cancer with metastases in 1-3 axillary lymph nodes, at least one metastasis larger than 2.0 mm. (from AJCC 8th Ed.)


benign fibrous histiocytoma of bone

description: A rare, benign neoplasm usually arising from the non-metaphyseal regions of long bones or pelvis. It is characterized by the presence of fibroblastic spindle cells arranged in a whorled storiform pattern, osteoclast-like giant cells, foam cells, inflammatory cells, hemosiderin deposition and stromal hemorrhage.


name: Grade 4 Small Intestine Infection, CTCAE

description: Life-threatening consequences; urgent intervention indicated


Other Secondary Neuroendocrine Tumors

description: Evidence of other secondary neuroendocrine tumors not specified elsewhere.


name: Musculoskeletal Chest Pain due to Intercostal Myofascial Injury

description: A condition in which there is musculoskeletal chest pain secondary to trauma to the connective tissues between the ribs. (ACC/AHA)


name: Adrenal Gland Intra-Operative Injury, CTCAE


name: Grade 4 Throat and Pharynx and Larynx Pain, CTCAE


Female sexual arousal disorder

description: A disorder characterized by a recurrent or persistent inability to attain or maintain until completion of sexual activity an adequate physical response of sexual excitement, consisting of vasocongestion in the pelvis, vaginal lubrication and expansion, and swelling of the external genitalia.


name: Mycosis Fungoides and Sezary Syndrome N2b TNM Finding v8

description: Clone positive. Note: A T-cell clone is defined by polymerase chain reaction (PCR) or Southern blot analysis of the TCR gene. (from AJCC 8th Ed.)


name: Drug or Chemical Induced Diabetes Mellitus with Mild Non-Proliferative Diabetic Retinopathy without Macular Edema, Unspecified Eye

description: Evidence of drug or chemical induced diabetes mellitus with mild non-proliferative diabetic retinopathy without macular edema in an unspecified eye.


name: Grade 5 Biliary Tree Stricture or Stenosis, CTCAE


Solid Alveolar Rhabdomyosarcoma

description: A morphologic variant of alveolar rhabdomyosarcoma.  It is characterized by the presence of a solid growth pattern and the absence of fibrovascular stroma.


name: Grade 3 Ventricular Arrhythmia NOS, CTCAE


Primary Lesion

description: A term that refers to a pathologic process in its original anatomic site of growth.


Poliovirus Receptor 3+ Staining Finding

description: A finding of 3+ staining for poliovirus receptor in a sample.


name: Adenosarcoma Pathologic Regional Lymph Nodes TNM Finding v7

description: A pathologic finding about one or more characteristics of adenosarcoma, following the rules of the TNM AJCC v7 classification system as they pertain to staging of the regional lymph nodes.


Ectopia

description: Abnormal position of a part or organ.


Penile Cancer TNM Finding v7

description: A finding about one or more characteristics of penile cancer, following the rules of the TNM AJCC v7 classification system.  Primary urethral carcinomas and melanomas are not included in this classification. (from AJCC 7th Ed.)


Spinal Injury Related to Birth

description: An injury to the spine sustained during the birthing process.


name: Grade 2 Central Nervous System Hemorrhage, CTCAE


name: Other Specified Rheumatoid Arthritis, Right Hand

description: Evidence of other specified rheumatoid arthritis in the right hand not specified elsewhere.


Cystic Lesion

description: A pathologic process that contains a single or multiple sac-like spaces.


Bone Cancer cM1b TNM Finding v8

description: Bone cancer with metastasis in the bone or other distant sites. (from AJCC 8th Ed.)


name: Frontal Lobe and Executive Function Deficit following Cerebral Infarction

description: Evidence of frontal lobe and executive function deficit following cerebral infarction.


Stage IVB Vaginal Cancer AJCC v6 and v7

description: Stage IVB includes: Any T, Any N, M1. M1: Distant metastasis. (AJCC 6th and 7th eds.)


Spinal Cord Infarct During Birth

description: Ischemic necrosis of the spinal cord due to spinal artery occlusion during the birthing process.


name: Ocular Adnexal Lymphoma Clinical Distant Metastasis TNM Finding v8

description: A clinical finding about one or more characteristics of ocular adnexal lymphoma, following the rules of the TNM AJCC v8 classification system as they pertain to distant metastases.


Grade 3 Thrush, CTCAE

description: IV antifungal intervention indicated


Disease Relapse/Refractory

description: The return of a disease or a disease becoming unresponsive to the current treatment.


Ptosis

description: A condition in which an organ or body tissue drops or bulges out of place.


Liver Progression GvHD

description: An increase by two times the upper limit of normal for ALT, alkaline phosphatase, and total bilirubin.


name: Other Nontraumatic Intracerebral Hemorrhage

description: Evidence of other nontraumatic intracerebral hemorrhage not specified elsewhere.


name: Grade 3 Cornea Infection with Unknown Absolute Neutrophil Count, CTCAE


Metastatic Meningioma

description: A meningioma that has spread from its original site of growth to another anatomic site.


name: Other Stimulant Abuse with Stimulant-Induced Psychotic Disorder with Hallucinations

description: Evidence of other stimulant abuse with stimulant-induced psychotic disorder with hallucinations not specified elsewhere.


name: Grade 3 Endocrine Disorders - Other, Specify, CTCAE

description: Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL


Residual schizophrenia

description: A subtype of schizophrenia in which the individual has suffered an episode of schizophrenia but there are no longer any delusions, hallucinations, disorganized speech or behavior. Residual symptoms are seen in the form of negative symptoms (such as flat affect or avolition) or attenuated positive symptoms (such as odd beliefs).


name: Brain and Spinal Cord Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


name: Decreased Time To Concomitant Drug Peak Blood Concentration

description: Decreased time following concomitant drug administration at which the peak drug blood concentration occurs.


Urethral Cancer cM0 TNM Finding v8

description: Urethral cancer without evidence of distant metastasis. (from AJCC 8th Ed.)


Prostate Cancer Clinical TNM Finding v8

description: A clinical finding about one or more characteristics of prostate cancer, following the rules of the TNM AJCC v8 classification system.


name: Nasopharyngeal Cancer Pathologic Distant Metastasis TNM Finding v6

description: A pathologic finding about one or more characteristics of nasopharyngeal cancer, following the rules of the TNM AJCC v6 classification system as they pertain to distant metastases.


name: Stage III Ampulla of Vater Cancer AJCC v7

description: Stage III includes: T4, Any N, M0. T4: Tumor invades peripancreatic soft tissues or other adjacent organs or structures other than the pancreas.  M0: No distant metastasis. (from AJCC 7th Ed.)


name: Carcinoma of the Eyelid Pathologic TNM Finding v7

description: A pathologic finding about one or more characteristics of carcinoma of the eyelid, following the rules of the TNM AJCC v7 classification system.  The surgical nature of the histopathology specimen should be noted including incisional biopsy, excisional biopsy, wide local excision, radical excision including exenteration.  The specimen should be carefully oriented and inked for margin evaluation.  (from AJCC 7th Ed.)


HIV Encephalopathy

description: Encephalopathy that is associated with human immunodeficiency virus (HIV) infection.


Grade 3 Platelet Count Decreased, CTCAE

description: <50,000-25,000/mm3; <50.0-25.0 x 10e9/L