colon signet ring cell adenocarcinoma

description: An invasive adenocarcinoma of the colon characterized by the presence of malignant glandular epithelial cells which contain prominent intracytoplasmic mucin (signet ring cells). The signet ring cells constitute more than 50% of the malignant cells.


colon adenocarcinoma

category: biolink:Disease biolink:DiseaseOrPhenotypicFeature biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing

description: A carcinoma that arises from glandular epithelial cells of the colon


jejunal neuroendocrine tumor G1

description: A well differentiated, low grade neuroendocrine tumor (carcinoid tumor) that arises from the jejunum. The mitotic count is less than 2 per 10 HPF and/or the Ki67 index is equal to or less than 2 percent.


squamous cell carcinoma of lip

description: A squamous cell carcinoma that involves the lip.


rectal cancer

description: A primary or metastatic malignant neoplasm that affects the rectum. Representative examples include carcinoma, lymphoma, and sarcoma.


ileocolitis

description: Ileocolitis or ileal Crohn's is the most common type of Crohn's disease. It affects both the ileum (small intestine) and the colon.


sigmoid disease

description: Pathological processes in the sigmoid colon region of the large intestine (intestine, large).


liver adenosquamous carcinoma

description: A rare carcinoma that arises from the intrahepatic bile ducts and is composed of malignant glandular cells and malignant squamous cells.


duodenogastric reflux

description: Retrograde flow of duodenal contents (bile acids; pancreatic juice) into the stomach.


laryngotracheoesophageal cleft type 4

description: Laryngo-tracheo-esophageal cleft (LC) type 4 is a serious congenital respiratory tract anomaly characterized by a cleft extending into the thoracic trachea and possibly down to the carina, with respiratory distress.


lipoma of stomach

description: A lipoma that involves the stomach.


name: maturity-onset diabetes of the young type 4

description: Monogenic diabetes caused by inactivating mutation(s) in the PDX1 gene, encoding pancreas/duodenum homeobox protein 1. Homozygous PDX1 mutations result in permanent neonatal diabetes.


small intestine neuroendocrine neoplasm

description: A neoplasm with neuroendocrine differentiation that arises from the small intestine. It includes well differentiated neuroendocrine tumors (low and intermediate grade) and poorly differentiated neuroendocrine carcinomas (high grade).


hepatitis E virus infection

description: Acute inflammation of the liver in humans; caused by hepatitis E virus, a non-enveloped single-stranded rna virus. Similar to hepatitis A, its incubation period is 15-60 days and is enterically transmitted, usually by fecal-oral transmission.


name: Alagille syndrome due to 20p12 microdeletion


appendix neuroendocrine neoplasm

description: A neoplasm with neuroendocrine differentiation that arises from the appendix. It includes well differentiated neuroendocrine tumors (low and intermediate grade) and poorly differentiated neuroendocrine carcinomas (high grade).


maxillary sinus carcinoma

description: A carcinoma that arises from the maxillary sinus. Representative examples include squamous cell carcinoma, adenocarcinoma, and adenoid cystic carcinoma.


hepatoerythropoietic porphyria

description: A very rare form of chronic hepatic porphyria characterized by bullous photodermatitis.


gastric fundus carcinoma

description: A carcinoma that arises from epithelial cells of the fundus of stomach.


microvillus inclusion disease

description: Microvillus inclusion disease (MVID) is a very rare, severe, malabsorbative syndrome characterized clinically by protracted or intractable neonatal secretory diarrhea and histologically by inclusion bodies on the intestinal epithelium.


Waardenburg syndrome type 4B

description: A subtype of Waardenburg syndrome type 4 (Waardenburg-Shah syndrome) caused by mutations in EDN3.


liver angiosarcoma

description: A malignant vascular neoplasm arising from the liver.


perinatal necrotizing enterocolitis

description: A fulminating disease of neonates in which there is extensive mucosal ulceration, pseudomembrane formation, submucosal hemorrhage, and necrosis usually of the right colon, cecum, terminal ileum, and appendix, possibly due to perinatal intestinal ischemia and bacterial invasion. Progression can lead to necrosis, perforation and/or scarring of the intestinal tract.


oral cavity carcinoma

description: A carcinoma arising in the oral cavity. Most oral cavity carcinomas are squamous cell carcinomas of the tongue, buccal mucosa, or gums. Less frequent morphologic variants include mucoepidermoid carcinoma and adenocarcinoma.


rectosigmoid junction neoplasm

description: A benign or malignant neoplasm that affects the rectosigmoid region. Representative examples of benign neoplasms include lipoma and leiomyoma. Representative examples of malignant neoplasms include carcinoma, lymphoma, and sarcoma. Rectosigmoid adenomas always exhibit epithelial dysplasia and are considered premalignant neoplasms.


colorectal Kaposi sarcoma

description: A Kaposi sarcoma that arises from the colon or rectum.


anal canal squamous cell carcinoma

description: A squamous cell carcinoma arising from the mucosa of the anal canal.


small intestine cancer

description: A primary or metastatic malignant neoplasm involving the small intestine.


name: gastric adenocarcinoma and proximal polyposis of the stomach

description: A rare hereditary gastric cancer characterized by proximal gastric polyposis and increased risk of early-onset, intestinal-type adenocarcinoma of the gastric body, with no duodenal or colorectal polyposis. This is an n-of-1 use case where only one patient or family has been described with this disorder.


name: undifferentiated carcinoma of liver and intrahepatic biliary tract

description: Undifferentiated carcinoma of liver and intrahepatic biliary tract is an extremely rare epithelial tumor of the liver and biliary tract which presents heterogenous histological findings and not yet fully defined clinicopathological characteristics. Patients usually present with nonspecific signs and symptoms, such as abdominal pain, nausea, vomiting, anorexia, weight loss and/or jaundice. Invasive growth, high metastatic potential and a rapid clinical course are typically associated.


hepatobiliary disorder

description: A non-neoplastic or neoplastic disorder that affects the liver, bile ducts, and gallbladder. Representative examples of non-neoplastic disorders include hepatitis, cirrhosis, cholangitis, and cholecystitis. Representative examples of neoplastic disorders include hepatocellular adenoma, hepatocellular carcinoma, and cholangiocarcinoma.


name: small intestinal intraepithelial neoplasia

description: A precancerous neoplastic process that affects the small intestine. It is characterized by low or high grade dysplasia of the mucosal epithelium. There is no evidence of invasion.


inflammatory bowel disease 26

description: An inflammatory bowel disease that has material basis in variation in the chromosome region 12q15.


chemical colitis

description: A colitis caused by the introduction of harsh chemicals to the colon by an enema or other procedure. Chemical colitis can resemble ulcerative colitis, infectious colitis and pseudomembranous colitis endoscopically.


gastric leiomyoma

description: A rare benign smooth muscle neoplasm arising from the wall of the stomach. It is characterized by the presence of spindle cells with cigar-shaped nuclei, interlacing fascicles, and a whorled pattern. Unlike gastrointestinal stromal tumors, gastric leiomyomas are by definition negative for CD34 and CD117 (C-KIT).


cholangiolocellular carcinoma

description: An intrahepatic cholangiocarcinoma that arises from the canals of Hering.


gastric liposarcoma

description: A malignant adipose tissue neoplasm of the stomach.


anal canal carcinoma

description: A carcinoma that arises from epithelial cells of the anal canal


insulin-resistance syndrome type B

description: Type B insulin-resistance syndrome belongs to the group of extreme insulin-resistance syndromes (which includes leprechaunism, the lipodystrophies, Rabson-Mendenhall syndrome, and type A insulin resistance syndrome) and occurs in the context of immune dysfunction.


colon juvenile polyp

description: A non-neoplastic hamartomatous polyp that arises from the colon. It is characterized by the presence of tortuous and cystically dilated glands, edematous changes, and inflammation.


name: cutaneous photosensitivity-lethal colitis syndrome

description: Cutaneous photosensitivity and lethal colitisis is a rare inflammatory bowel disease characterized by early cutaneous photosensitivity manifesting by sun-induced facial erythematous and vesicular lesions and severe recurent colitis which lead to untreatable diarrhea. There have been no further descriptions in the literature since 1991.


intestinal motility disease

description: A disease that has its basis in the disruption of intestinal motility.


bacterial gastritis

description: Gastritis resulting from bacteria.


benign neoplasm of appendix

description: A benign neoplasm that involves the vermiform appendix.


anus leiomyosarcoma

description: An aggressive malignant smooth muscle neoplasm, arising from the anus. It is characterized by a proliferation of neoplastic spindle cells.


liver adenomatosis

description: A rare neoplastic disease characterized by the presence of ten or more hepatocellular adenomas in a background of normal appearing hepatic parenchyma. The majority of reported cases are female. There is no association with steroid use. The condition is considered benign, although the risk of complications (such as malignant transformation or spontaneous rupture with intraperitoneal hemorrhage) is much higher than in isolated hepatic adenoma. Hepatocellular carcinoma develops in less than 10% of cases.


name: megacystis-microcolon-intestinal hypoperistalsis syndrome 5


Epstein-Barr virus hepatitis

description: A viral hepatitis that results in inflammation, located in liver, has material basis in Human herpesvirus 4 and has symptom headache, has symptom fatigue, has symptom fever, has symptom abdominal pain, has symptom nausea, and has symptom jaundice.


protoporphyria, erythropoietic, 1

description: Erythropoietic protoporphyria caused by a compound heterozygous or homozygous mutation in the gene encoding ferrochelatase (FECH) on chromosome 18q21.


name: acute infantile liver failure due to synthesis defect of mtDNA-encoded proteins

description: Acute infantile liver failure due to mtDNA-encoded proteins synthesis defect is a very rare mitochondrial respiratory chain deficiency described in fewer than 10 infants, primarily of middle Eastern descent, and characterized clinically by transient but life-threatening liver failure with elevated liver enzymes, jaundice, vomiting, coagulopathy, hyperbilirubinemia, and lactic acidemia.


name: benign recurrent intrahepatic cholestasis

description: Benign recurrent intrahepatic cholestasis (BRIC) is a hereditary liver disorder characterized by intermittent episodes of intrahepatic cholestasis, generally without progression to chronic liver damage. BRIC is now believed to belong to a clinical spectrum of intrahepatic cholestatic disorders that ranges from the mild intermittent attacks in BRIC to the severe, chronic and progressive cholestasis seen in progressive familial intrahepatic cholestasis (PFIC).


xanthogranulomatous cholecystitis

description: Cholecystitis that is characterized by nodules containing lipid.


opioid-induced constipation

description: A constipation disorder caused by use of opioids. OIC may present immediately when a patient takes the opioid, or it may present gradually during opioid therapy.


X-linked erythropoietic protoporphyria

description: X-linked form of erythropoietic protoporphyria.


jejunal adenocarcinoma

description: A adenocarcinoma that involves the jejunum.


Waardenburg syndrome type 4A

description: A subtype of Waardenburg syndrome type 4 (Waardenburg-Shah syndrome) caused by mutations in EDNRB.


name: Lugano Classification Stage IV Adult Non-Hodgkin Lymphoma AJCC v8

description: Stage IV: Diffuse or disseminated involvement of one or more extralymphatic organs, with or without associated lymph node involvement; or noncontiguous extralymphatic organ involvement in conjunction with nodal stage II disease; or any extralymphatic organ involvement in nodal stage III disease. Stage IV includes any involvement of the CSF, bone marrow, liver, or lungs (other than by direct extension in stage IIE disease). (from AJCC 8th Ed.)


name: mortality factor 4-like protein 1 isoform h3 (human)

description: A mortality factor 4-like protein 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9UBU8-3.


name: US6NL_HUMAN USP6 N-terminal-like protein (sprot)

description: A USP6 N-terminal-like protein that is encoded in the genome of human.


name: USP6 N-terminal-like protein isoform h2 (human)

description: A USP6 N-terminal-like protein (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q92738-2.


name: USP6 N-terminal-like protein isoform h1 (human)

description: A USP6 N-terminal-like protein (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q92738-1.


name: two pore channel protein 1 isoform h1 (human)

description: A two pore channel protein 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9ULQ1-1.


name: alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A isoform 1 (human)

description: An alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A isoform 1 that is encoded in the genome of human.


protein FAM227B isoform h1 (human)

A protein FAM227B (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q96M60-1.


F227B_HUMAN Protein FAM227B (sprot)

A protein FAM227B that is encoded in the genome of human.


protein FAM227B isoform h2 (human)

A protein FAM227B (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q96M60-2.


name: microtubule-associated tumor suppressor 1 homolog isoform m1 (mouse)

description: A microtubule-associated tumor suppressor 1 homolog (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q5HZI1-1.


name: cholesteryl ester transfer protein isoform h2 (human)

description: A cholesteryl ester transfer protein (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P11597-2.


name: CETP_HUMAN Cholesteryl ester transfer protein (sprot)

description: A cholesteryl ester transfer protein that is encoded in the genome of human.


name: cholesteryl ester transfer protein O-glycosylated 1 (human)

description: A cholesteryl ester transfer protein (human) that has been O-glycosylated at the residue equivalent to Thr-266 of the amino acid sequence represented by UniProtKB:P11597-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P11597-1, Thr-266, MOD:00005~GNO:G43417UB.


name: cholesteryl ester transfer protein, signal peptide removed form (human)

description: A cholesteryl ester transfer protein (human) that has had the signal peptide removed. Example: UniProtKB:P11597-1, 18-493.


name: cholesteryl ester transfer protein isoform h1 (human)

description: A cholesteryl ester transfer protein (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P11597-1.


name: general transcription factor II-I repeat domain-containing protein 2A deaminated 1 (human)

description: A general transcription factor II-I repeat domain-containing protein 2A (human) that has been deaminated on the residue at the position equivalent to Gln-524 of the amino acid sequence represented by UniProtKB:Q86UP8-1. Example: UniProtKB:Q86UP8-1, Gln-524, MOD:00685.


name: signal transducer and activator of transcription 5A isoform h2 (human)

description: A signal transducer and activator of transcription 5A (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P42229-2.


name: signal transducer and activator of transcription 5a

description: A signal transducer and transcription activator STAT that is a translation product of the human STAT5A gene or a 1:1 ortholog thereof.


name: STA5A_RAT Signal transducer and activator of transcription 5A (sprot)

description: A signal transducer and activator of transcription 5a that is encoded in the genome of rat.


name: signal transducer and activator of transcription 5A phosphorylated 1 (mouse)

description: A signal transducer and activator of transcription 5A (mouse) that has been phosphorylated at Ser-779. UniProtKB:P42230, Ser-779, MOD:00046.


name: signal transducer and activator of transcription 5A phosphorylated 1 (human)

description: A signal transducer and activator of transcription 5A (human) that has been phosphorylated on the residue at the position equivalent to Tyr-694 of the amino acid sequence represented by UniProtKB:P42229-1. Example: UniProtKB:P42229-1, Tyr-694, MOD:00048.


name: signal transducer and activator of transcription 1 isoform c (worm)

description: A signal transducer and activator of transcription 1 (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9NAD6-3.


name: signal transducer and activator of transcription 5A methylated 1 (human)

description: A signal transducer and activator of transcription 5A (human) that has been methylated on the residue at the position equivalent to Cys-101 of the amino acid sequence represented by UniProtKB:P42229-1. Example: UniProtKB:P42229-1, Cys-101, MOD:00660.


name: signal transducer and activator of transcription 1 isoform b (worm)

description: A signal transducer and activator of transcription 1 (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9NAD6-2.


name: signal transducer and activator of transcription 5A isoform h1 (human)

description: A signal transducer and activator of transcription 5A (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P42229-1.


name: STA5A_MOUSE Signal transducer and activator of transcription 5A (sprot)

description: A signal transducer and activator of transcription 5a that is encoded in the genome of mouse.


name: signal transducer and activator of transcription 1 isoform a (worm)

description: A signal transducer and activator of transcription 1 (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9NAD6-1.


name: STA5A_HUMAN Signal transducer and activator of transcription 5A (sprot)

description: A signal transducer and activator of transcription 5a that is encoded in the genome of human.


name: signal transducer and activator of transcription 5A isoform rStat5A1 (rat)

description: A signal transducer and activator of transcription 5A (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q62771-1.


name: signal transducer and activator of transcription 5A isoform rStat5A2 (rat)

description: A signal transducer and activator of transcription 5A (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q62771-2.


name: STAT1_CAEEL Signal transducer and activator of transcription 1 (sprot)

description: A signal transducer and activator of transcription 5a that is encoded in the genome of worm.


name: collagen and calcium-binding EGF domain-containing protein 1 isoform h2 (human)

description: A collagen and calcium-binding EGF domain-containing protein 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q6UXH8-2.


name: SOSSC_DANRE SOSS complex subunit C (sprot)

description: A SOSS complex subunit C that is encoded in the genome of zebrafish.


alpha-mannosidase 2x isoform h3 (human)

An alpha-mannosidase 2x (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P49641-3.


name: ribonuclease T2 N-glycosylated 2 (human)

description: A ribonuclease T2 (human) that has been N-glycosylated at the residue equivalent to Asn-212 of the amino acid sequence represented by UniProtKB:O00584-1, in which the glycan composition is represented by GlyTouCan:G87051GH. Example: UniProtKB:O00584-1, Asn-212, MOD:00160~GNO:G87051GH.


RNT2_HUMAN Ribonuclease T2 (sprot)

A ribonuclease T2 that is encoded in the genome of human.


name: ribonuclease T2, signal peptide removed form (human)

description: A ribonuclease T2 (human) that has had the signal peptide removed. Example: UniProtKB:O00584-1, 25-256.


ribonuclease T2 cysteinylated 1 (human)

A ribonuclease T2 (human) that has been cysteinylated on the residue at the position equivalent to Cys-13 of the amino acid sequence represented by UniProtKB:O00584-1. Example: UniProtKB:O00584-1, Cys-13, MOD:00765.


name: ribonuclease T2 N-glycosylated 1 (human)

description: A ribonuclease T2 (human) that has been N-glycosylated at the residue equivalent to Asn-212 of the amino acid sequence represented by UniProtKB:O00584-1, in which the glycan composition is represented by GlyTouCan:G60923RB. Example: UniProtKB:O00584-1, Asn-212, MOD:00160~GNO:G60923RB.


ribonuclease T2 isoform h1 (human)

A ribonuclease T2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O00584-1.


ribonuclease T2 methylated 1 (human)

A ribonuclease T2 (human) that has been methylated on the residue at the position equivalent to Cys-184 of the amino acid sequence represented by UniProtKB:O00584-1. Example: UniProtKB:O00584-1, Cys-184, MOD:00660.


ribonuclease T2 isoform h2 (human)

A ribonuclease T2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O00584-2.


ribonuclease T2 cysteinylated 2 (human)

A ribonuclease T2 (human) that has been cysteinylated on the residue at the position equivalent to Cys-121 of the amino acid sequence represented by UniProtKB:O00584-1. Example: UniProtKB:O00584-1, Cys-121, MOD:00765.


name: SYW_ECOLI Tryptophan--tRNA ligase (sprot)

description: A tryptophan--tRNA ligase that is encoded in the genome of Escherichia coli K-12.


tryptophan--tRNA ligase

A protein that is a translation product of the Escherichia coli K-12 trpS gene or a 1:1 ortholog thereof.


name: PIN2/TERF1-interacting telomerase inhibitor 1 isoform h2 (human)

description: A PIN2/TERF1-interacting telomerase inhibitor 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q96BK5-2.


pin2-interacting protein X1

A protein that is a translation product of the human PINX1 gene or a 1:1 ortholog thereof.


PXR1_SCHPO Protein pxr1 (sprot)

A pin2-interacting protein X1 that is encoded in the genome of Schizosaccharomyces pombe 972h-.


name: PINX1_HUMAN PIN2/TERF1-interacting telomerase inhibitor 1 (sprot)

description: A pin2-interacting protein X1 that is encoded in the genome of human.


name: PINX1_MOUSE PIN2/TERF1-interacting telomerase inhibitor 1 (sprot)

description: A pin2-interacting protein X1 that is encoded in the genome of mouse.


name: PIN2/TERF1-interacting telomerase inhibitor 1 isoform h1 (human)

description: A PIN2/TERF1-interacting telomerase inhibitor 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q96BK5-1.


name: PINX1_RAT PIN2/TERF1-interacting telomerase inhibitor 1 (sprot)

description: A pin2-interacting protein X1 that is encoded in the genome of rat.


Major microspecies at pH 7.3.


Cryogenic Burn

description: Local tissue damage due to exposure to extreme cold.


3-oxo-23-hydroxyurs-12-en-28-oic acid

A pentacyclic triterpenoid that is urs-12-ene substituted by an oxo group at position 3, a carboxy group at position 28 and a hydroxy group at position 23. It has been isolated from Juglans sinensis.


mucin-6 N-glycosylated 4 (human)

A mucin-6 (human) that has been N-glycosylated at the residue equivalent to Asn-902 of the amino acid sequence represented by UniProtKB:Q6W4X9-1, in which the glycan composition is represented by GlyTouCan:G66933CM. Example: UniProtKB:Q6W4X9-1, Asn-902, MOD:00160~GNO:G66933CM.


Supratentorial Gliosarcoma

description: A gliosarcoma arising from the supratentorial region.


Cerebral Glioblastoma

description: A glioblastoma that occurs in the cerebrum.


name: transcription factor HES-3 isoform 1 (rat)

description: A transcription factor HES-3 isoform 1 that is encoded in the genome of rat.


A limonoid that is azadiradione substituted by a hydroxy group at position 17. It has been isolated from Azadirachta indica.


name: AP-1 complex subunit beta-1 deaminated 2 (human)

description: An AP-1 complex subunit beta-1 (human) that has been deaminated on the residue at the position equivalent to Gln-353 of the amino acid sequence represented by UniProtKB:Q10567-1. Example: UniProtKB:Q10567-1, Gln-353, MOD:00685.


name: UPF0688 protein C1orf174 homolog isoform 1 (zebrafish)

description: A UPF0688 protein C1orf174 homolog (zebrafish) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q1L9C7-1.


name: membrane cofactor protein isoform h2 (human)

description: A membrane cofactor protein (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P15529-10.


name: 2,4-dichlorobenzoic acid 1,2,4-triazol-1-ylmethyl ester


ELAV-like protein 4 isoform m2 (mouse)

An ELAV-like protein 4 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q61701-2.


name: zinc finger protein 385A isoform 2 (mouse)

description: A zinc finger protein 385A isoform 1 that is encoded in the genome of mouse.


name: Z385A_MOUSE Zinc finger protein 385A (sprot)

description: A zinc finger protein 385A that is encoded in the genome of mouse.


name: zinc finger protein 385A isoform 1 (mouse)

description: A zinc finger protein 385A isoform 4 that is encoded in the genome of mouse.


name: YBEY_ECOLI Endoribonuclease YbeY (sprot)

description: An endoribonuclease YbeY that is encoded in the genome of Escherichia coli K-12.


name: CRIPT_RAT Cysteine-rich PDZ-binding protein (sprot)

description: A cysteine-rich PDZ-binding protein that is encoded in the genome of rat.


name: cysteine-rich PDZ-binding protein isoform 1 (rat)

description: A cysteine-rich PDZ-binding protein isoform 1 that is encoded in the genome of rat.


tetraspanin-33 isoform m2 (mouse)

A tetraspanin-33 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8R3S2-2.


name: RAF proto-oncogene serine/threonine-protein kinase sequence variant N262L phosphorylated 1 (human)

description: A RAF proto-oncogene serine/threonine-protein kinase (human) that has a Leu residue at the position equivalent to Asn-262 of the amino acid sequence represented by UniProtKB:P04049-1 and that has been phosphorylated on the residue at the position equivalent to Ser-621. Example: UniProtKB:P04049-1, Asn-262, CHEBI:30006|Ser-621, MOD:00046.


name: VHT1_SCHPO Vitamin H transporter 1 (sprot)

description: A protein that is a translation product of the vht1 gene in Schizosaccharomyces pombe 972h-.


NRAM_I68A3 Neuraminidase (sprot)

A neuraminidase subtype N4 (Influenza A virus) that is encoded in the genome of the H8N4 strain A/Turkey/Ontario/6118/1968.


name: FR1L5_MOUSE Fer-1-like protein 5 (sprot)

description: A Fer-1-like protein 5 that is encoded in the genome of mouse.


name: probable ATP-dependent RNA helicase DDX59 isoform m2 (mouse)

description: A probable ATP-dependent RNA helicase DDX59 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9DBN9-2.


name: voltage-dependent calcium channel gamma-5 subunit isoform 1 (mouse)

description: A voltage-dependent calcium channel gamma-5 subunit isoform 1 that is encoded in the genome of mouse.


name: voltage-dependent calcium channel gamma-5 subunit

description: A protein that is a translation product of the human CACNG5 gene or a 1:1 ortholog thereof.


name: CCG5_MOUSE Voltage-dependent calcium channel gamma-5 subunit (sprot)

description: A voltage-dependent calcium channel gamma-5 subunit that is encoded in the genome of mouse.


name: voltage-dependent calcium channel gamma-5 subunit isoform 1 (human)

description: A voltage-dependent calcium channel gamma-5 subunit isoform 1 that is encoded in the genome of human.


name: CCG5_HUMAN Voltage-dependent calcium channel gamma-5 subunit (sprot)

description: A voltage-dependent calcium channel gamma-5 subunit that is encoded in the genome of human.


name: CCG5_RAT Voltage-dependent calcium channel gamma-5 subunit (sprot)

description: A voltage-dependent calcium channel gamma-5 subunit that is encoded in the genome of rat.


name: voltage-dependent calcium channel gamma-5 subunit isoform 1

description: A voltage-dependent calcium channel gamma-5 subunit that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9UF02-1 or a 1:1 ortholog thereof.


benign granular cell tumor

description: A granular cell tumor that is confined to the site of origin, without metastatic potential.


cardiac granular cell neoplasm

description: A very rare granular cell tumor that arises from the heart.


name: benign peripheral nerve granular cell tumor

description: A benign granular cell tumor that involves the nerve.


name: FB212_ARATH F-box protein At3g59150 (sprot)

description: A protein that is a translation product of the At3g59150 gene in Arabidopsis thaliana.


name: THO7B_ARATH THO complex subunit 7B (sprot)

description: A protein that is a translation product of the THO7B gene in Arabidopsis thaliana.


name: tubulin epsilon and delta complex protein 2 cysteinylated 1 (human)

description: A tubulin epsilon and delta complex protein 2 (human) that has been cysteinylated on the residue at the position equivalent to Cys-331 of the amino acid sequence represented by UniProtKB:Q7L2K0-1. Example: UniProtKB:Q7L2K0-1, Cys-331, MOD:00765.


name: leucine-rich repeat-containing protein 51 isoform h2 (human)

description: A leucine-rich repeat-containing protein 51 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q96E66-2.


name: LRC51_HUMAN Leucine-rich repeat-containing protein 51 (sprot)

description: A leucine-rich repeat-containing protein 51 that is encoded in the genome of human.


name: leucine-rich repeat-containing protein 51 isoform h5 (human)

description: A leucine-rich repeat-containing protein 51 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q96E66-5.


name: leucine-rich repeat-containing protein 51 isoform h3 (human)

description: A leucine-rich repeat-containing protein 51 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q96E66-3.


name: leucine-rich repeat-containing protein 51 isoform h1 (human)

description: A leucine-rich repeat-containing protein 51 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q96E66-1.


name: leucine-rich repeat-containing protein 51 isoform h4 (human)

description: A leucine-rich repeat-containing protein 51 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q96E66-4.


name: leucine-rich repeat-containing protein 51 isoform h6 (human)

description: A leucine-rich repeat-containing protein 51 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q96E66-6.


Multiple hamartoma of lung

description: The presence of multiple hamartomas in the lungs.  Hamartomas are usually solitary lesions on chest-x-rays.  Multiple lung hamartomas are rare.


name: PRRX2_HUMAN Paired mesoderm homeobox protein 2 (sprot)

description: A paired mesoderm homeobox protein 2 that is encoded in the genome of human.


name: vitamin K-dependent protein C O-glycosylated 2 (human)

description: A vitamin K-dependent protein C (human) that has been O-glycosylated at the residue equivalent to Thr-19 of the amino acid sequence represented by UniProtKB:P04070-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P04070-1, Thr-19, MOD:00005~GNO:G43417UB.


Increased CSF alanine concentration

category: biolink:PhenotypicFeature biolink:DiseaseOrPhenotypicFeature biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing

description: Abnormally increased levels of alanine in cerebrospinal fluid.


name: exopolyphosphatase PRUNE1 isoform 1 (rat)

description: An exopolyphosphatase PRUNE1 isoform 1 that is encoded in the genome of rat.


name: smad-related protein daf-14 isoform b (worm)

description: A smad-related protein daf-14 (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:F5GUE5-1.


A triazolopyridazine that is tetrahydro-1H-[1,2,4]triazolo[1,2-a]pyridazine which is substituted at positions 1, 3, and 4 by oxo, sulfanyl  and 4-chloro-2-fluoro-5-[(2-methoxy-2-oxoethyl)sulfanyl]phenyl groups, respectively. The active metabolite of the proherbicide fluthiacet-methyl.


name: SPRY domain-containing SOCS box protein 1 isoform 1 (human)

description: A SPRY domain-containing SOCS box protein 1 isoform 1 that is encoded in the genome of human.


name: SPRY domain-containing SOCS box protein 1 isoform 1

description: A SPRY domain-containing SOCS box protein 1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q96BD6-1 or a 1:1 ortholog thereof.


name: SPRY domain-containing SOCS box protein 1 isoform 1 (mouse)

description: A SPRY domain-containing SOCS box protein 1 isoform 1 that is encoded in the genome of mouse.


name: HCF1_CAEEL Host cell factor homolog hcf-1 (sprot)

description: A host cell factor 2 that is encoded in the genome of worm.


host cell factor 2

A protein that is a translation product of the human HCFC2 gene or a 1:1 ortholog thereof.


HCFC2_MOUSE Host cell factor 2 (sprot)

A host cell factor 2 that is encoded in the genome of mouse.


HCFC2_RAT Host cell factor 2 (sprot)

A host cell factor 2 that is encoded in the genome of rat.


host cell factor 2 deaminated 2 (human)

A host cell factor 2 (human) that has been deaminated on the residue at the position equivalent to Gln-747 of the amino acid sequence represented by UniProtKB:Q9Y5Z7-1. Example: UniProtKB:Q9Y5Z7-1, Gln-747, MOD:00685.


HCFC2_HUMAN Host cell factor 2 (sprot)

A host cell factor 2 that is encoded in the genome of human.


host cell factor 2 deaminated 1 (human)

A host cell factor 2 (human) that has been deaminated on the residue at the position equivalent to Asn-371 of the amino acid sequence represented by UniProtKB:Q9Y5Z7-1. Example: UniProtKB:Q9Y5Z7-1, Asn-371, MOD:00684.


host cell factor 2 isoform h1 (human)

A host cell factor 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9Y5Z7-1.


host cell factor 2 isoform h2 (human)

A host cell factor 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9Y5Z7-2.


treacle protein isoform h5 (human)

A treacle protein (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q13428-5.


name: tyrosine-protein phosphatase non-receptor type substrate 1 N-glycosylated 33 (rat)

description: A tyrosine-protein phosphatase non-receptor type substrate 1 (rat) that has been N-glycosylated at the residue equivalent to Asn-93 of the amino acid sequence represented by UniProtKB:P97710-1, in which the glycan composition is represented by GlyTouCan:G67324HN. Example: UniProtKB:P97710-1, Asn-93, MOD:00160~GNO:G67324HN.


name: RS16_PSEAE Small ribosomal subunit protein bS16 (sprot)

description: A small ribosomal subunit protein bS16 that is encoded in the genome of Pseudomonas aeruginosa PAO1.


name: SMAD2_DANRE Mothers against decapentaplegic homolog 2 (sprot)

description: A smad2 that is encoded in the genome of zebrafish.


Glutathionuria

description: Level of glutathione in the urine above the upper limit of normal.


name: CD209 antigen-like protein D isoform m2 (mouse)

description: A CD209 antigen-like protein D (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q91ZW8-2.


name: prenylcysteine oxidase 1 N-glycosylated 11 (rat)

description: A prenylcysteine oxidase 1 (rat) that has been N-glycosylated at the residue equivalent to Asn-352 of the amino acid sequence represented by UniProtKB:Q99ML5-1, in which the glycan composition is represented by GlyTouCan:G62765YT. Example: UniProtKB:Q99ML5-1, Asn-352, MOD:00160~GNO:G62765YT.


name: intermediate filament protein ifb-2 isoform a (worm)

description: An intermediate filament protein ifb-2 (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q19286-1.


name: sodium channel subunit beta-3, signal peptide removed form (human)

description: A sodium channel subunit beta-3 (human) that has had the signal peptide removed. UniProtKB:Q9NY72, 23-215.


name: Increased level of galactitol in red blood cells

description: An increase in the level of galactitol in the red blood cells.


name: GATOR2 complex protein MIOS methylated 2 (human)

description: A GATOR2 complex protein MIOS (human) that has been methylated on the residue at the position equivalent to Cys-191 of the amino acid sequence represented by UniProtKB:Q9NXC5-1. Example: UniProtKB:Q9NXC5-1, Cys-191, MOD:00660.


name: BARX1_HUMAN Homeobox protein BarH-like 1 (sprot)

description: A homeobox protein BarH-like 1 that is encoded in the genome of human.


homeobox protein BarH-like 1

A protein that is a translation product of the human BARX1 gene or a 1:1 ortholog thereof.


homeobox protein BarH-like 1 isoform 1

A homeobox protein BarH-like 1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9HBU1-1 or a 1:1 ortholog thereof.


name: homeobox protein BarH-like 1 isoform 1 (mouse)

description: A homeobox protein BarH-like 1 isoform 1 that is encoded in the genome of mouse.


name: BARX1_MOUSE Homeobox protein BarH-like 1 (sprot)

description: A homeobox protein BarH-like 1 that is encoded in the genome of mouse.


name: homeobox protein BarH-like 1 isoform 1 (human)

description: A homeobox protein BarH-like 1 isoform 1 that is encoded in the genome of human.


name: BAX1B_CHICK Homeobox protein BarH-like 1b (sprot)

description: A homeobox protein BarH-like 1 that is encoded in the genome of chicken.


name: homeobox protein BarH-like 1 isoform h2 (human)

description: A homeobox protein BarH-like 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9HBU1-2.


name: BARX1_DANRE Homeobox protein BarH-like 1 (sprot)

description: A homeobox protein BarH-like 1 that is encoded in the genome of zebrafish.


cyclin-T1 isoform h1 (human)

A cyclin-T1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O60563-1.


name: PO3F1_DANRE POU domain, class 3, transcription factor 1 (sprot)

description: A POU domain, class 3, transcription factor 1 that is encoded in the genome of zebrafish.


name: 6-methyl-4-oxoquinolizine-1,3-dicarboxylic acid diethyl ester


name: YFCD_ECOLI Uncharacterized Nudix hydrolase YfcD (sprot)

description: An uncharacterized Nudix hydrolase YfcD that is encoded in the genome of Escherichia coli K-12.


uncharacterized Nudix hydrolase YfcD

A protein that is a translation product of the Escherichia coli K-12 yfcD gene or a 1:1 ortholog thereof.


name: bromodomain adjacent to zinc finger domain protein 2A methylated 2 (human)

description: A bromodomain adjacent to zinc finger domain protein 2A (human) that has been methylated on the residue at the position equivalent to Cys-1720 of the amino acid sequence represented by UniProtKB:Q9UIF9-1. Example: UniProtKB:Q9UIF9-1, Cys-1720, MOD:00660.


name: gamma-aminobutyric acid receptor subunit rho-2 isoform 2 (mouse)

description: A gamma-aminobutyric acid receptor subunit rho-2 isoform 2 that is encoded in the genome of mouse.


name: phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN sequence variant Q245*, initiator methionine removed form (human)

description: A phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN (human) that has has been truncated after the position equivalent to Pro-244 of the amino acid sequence represented by UniProtKB:P60484-1 and that has had the initiator methionine removed. Example: UniProtKB:P60484-1, 2-244.


name: GSTUP_ARATH Glutathione S-transferase U25 (sprot)

description: A protein that is a translation product of the GSTU25 gene in Arabidopsis thaliana.


degenerin unc-8 isoform b (worm)

A degenerin unc-8 (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q21974-2.


UNC8_CAEEL Degenerin unc-8 (sprot)

A protein that is a translation product of the unc-8 gene in worm.


degenerin unc-8 isoform c (worm)

A degenerin unc-8 (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q21974-3.


degenerin unc-8 isoform a (worm)

A degenerin unc-8 (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q21974-1.


degenerin unc-8 isoform d (worm)

A degenerin unc-8 (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q21974-4.


ELAEODENDROSIDE W

A cardenolide glycoside that is 3,5,11,14-tetrahydroxy-19-oxocard-20(22)-enolide glycosylated at position 3 by a beta-allosyl-(1->4)-beta-6-deoxyallosyl group. Isolated from Elaeodendron alluaudianum, it exhibits antiproliferative activity against human ovarian cancer and human histiocytic lymphoma cell lines.


dysgerminoma of ovary

description: A malignant germ cell tumor arising from the ovary. Morphologically, it is identical to seminoma and consists of a monotonous population of germ cells with abundant pale cytoplasm and uniform nuclei. The stroma invariably contains chronic inflammatory cells, mostly T-lymphocytes. It responds to chemotherapy or radiotherapy and the prognosis relates to the tumor stage.


pediatric ovarian dysgerminoma

description: A dysgerminoma that arises from the ovary and occurs in children.


name: G protein-activated inward rectifier potassium channel 3 isoform 1 (rat)

description: A G protein-activated inward rectifier potassium channel 3 isoform 1 that is encoded in the genome of rat.


name: KCNJ9_RAT G protein-activated inward rectifier potassium channel 3 (sprot)

description: A G protein-activated inward rectifier potassium channel 3 that is encoded in the genome of rat.


name: proteasome subunit beta type-5 isoform h3 (human)

description: A proteasome subunit beta type-5 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P28074-3.


name: integrin alpha-7 isoform rAlpha-7X1A (rat)

description: An integrin alpha-7 (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q63258-2.


Edematous Scrotum

description: An indication that on visual inspection the scrotal skin is found to have become taut due to excessive fluid.


protocadherin-15 isoform m2 (mouse)

A protocadherin-15 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q99PJ1-2.


name: SERC_SCHPO Putative phosphoserine aminotransferase (sprot)

description: A phosphoserine aminotransferase that is encoded in the genome of Schizosaccharomyces pombe 972h-.


name: tyrosine-protein kinase JAK3 phosphorylated 2 (human)

description: A tyrosine-protein kinase JAK3 (human) that has been phosphorylated on the residues at the positions equivalent to Tyr-904 and Tyr-939 of the amino acid sequence represented by UniProtKB:P52333-1. Example: UniProtKB:P52333-1, Tyr-904/Tyr-939, MOD:00048.


name: peroxisomal trans-2-enoyl-CoA reductase isoform 1

description: A peroxisomal trans-2-enoyl-CoA reductase that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9BY49-1 or a 1:1 ortholog thereof.


name: peroxisomal trans-2-enoyl-CoA reductase isoform 1 (human)

description: A peroxisomal trans-2-enoyl-CoA reductase isoform 1 that is encoded in the genome of human.


name: peroxisomal trans-2-enoyl-CoA reductase isoform 1 (rat)

description: A peroxisomal trans-2-enoyl-CoA reductase isoform 1 that is encoded in the genome of rat.


name: peroxisomal trans-2-enoyl-CoA reductase isoform 1 (mouse)

description: A peroxisomal trans-2-enoyl-CoA reductase isoform 1 that is encoded in the genome of mouse.


name: SCM2A_DANRE Calcium-binding mitochondrial carrier protein SCaMC-2-A (sprot)

description: A protein that is a translation product of the slc25a25a gene in zebrafish.


name: OFP3_ARATH Transcription repressor OFP3 (sprot)

description: A protein that is a translation product of the OFP3 gene in Arabidopsis thaliana.


name: CD209 antigen-like protein B isoform m3 (mouse)

description: A CD209 antigen-like protein B (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8CJ91-3.


spermine oxidase isoform 1 (human)

A spermine oxidase isoform 1 that is encoded in the genome of human.


spermine oxidase

A protein that is a translation product of the human SMOX gene or a 1:1 ortholog thereof.


spermine oxidase isoform 1 (mouse)

A spermine oxidase isoform 1 that is encoded in the genome of mouse.


SMOX_MOUSE Spermine oxidase (sprot)

A spermine oxidase that is encoded in the genome of mouse.


spermine oxidase isoform 10 (mouse)

A spermine oxidase isoform 3 that is encoded in the genome of mouse.


spermine oxidase isoform m7 (mouse)

A spermine oxidase (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q99K82-7.


spermine oxidase isoform 6

A spermine oxidase that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9NWM0-6 or a 1:1 ortholog thereof.


SMOX_HUMAN Spermine oxidase (sprot)

A spermine oxidase that is encoded in the genome of human.


spermine oxidase isoform m8 (mouse)

A spermine oxidase (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q99K82-8.


spermine oxidase isoform 6 (human)

A spermine oxidase isoform 6 that is encoded in the genome of human.


spermine oxidase isoform h2 (human)

A spermine oxidase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9NWM0-2.


spermine oxidase isoform 1

A spermine oxidase that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9NWM0-1 or a 1:1 ortholog thereof.


spermine oxidase isoform m6 (mouse)

A spermine oxidase (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q99K82-6.


spermine oxidase isoform 3

A spermine oxidase that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9NWM0-3 or a 1:1 ortholog thereof.


spermine oxidase isoform m4 (mouse)

A spermine oxidase (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q99K82-4.


spermine oxidase isoform m5 (mouse)

A spermine oxidase (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q99K82-5.


spermine oxidase isoform h5 (human)

A spermine oxidase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9NWM0-5.


spermine oxidase isoform 3 (human)

A spermine oxidase isoform 3 that is encoded in the genome of human.


spermine oxidase isoform m9 (mouse)

A spermine oxidase (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q99K82-9.


spermine oxidase isoform h4 (human)

A spermine oxidase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9NWM0-4.


spermine oxidase isoform 2 (mouse)

A spermine oxidase isoform 6 that is encoded in the genome of mouse.


name: UBR7_DICDI Putative E3 ubiquitin-protein ligase ubr7 (sprot)

description: A putative E3 ubiquitin-protein ligase UBR7 that is encoded in the genome of Dictyostelium discoideum.


name: myosin-9, initiator methionine removed form (human)

description: A myosin-9 (human) that has had the initiator methionine removed. UniProtKB:P35579, 2-1960.


(S)-haloxyfop

A 2-(4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}phenoxy)propanoic acid that has S configuration. It is the least-active enantiomer of the (racemic) herbicide haloxyfop.


HALOXYFOP-R-METHYL

A 2-(4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}phenoxy)propanoic acid that has R configuration. It is the most active enantiomer of the (racemic) herbicide haloxyfop and is used (particularly as the corresponding methyl and ethoxyethyl ester proherbicides (haloxyfop-P-methyl and haloxyfop-P-etotyl, respectively) to control annual and perrenial grasses in a variety of crops.


name: TRXR1_CAEEL Thioredoxin reductase 1 (sprot)

description: A protein that is a translation product of the trxr-1 gene in worm.


name: neuropeptide-like protein 38 isoform b (worm)

description: A neuropeptide-like protein 38 (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:G3MU46-1.


name: NLP38_CAEEL Neuropeptide-like protein 38 (sprot)

description: A protein that is a translation product of the nlp-38 gene in worm.


name: neuropeptide-like protein 38 isoform a (worm)

description: A neuropeptide-like protein 38 (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:G3MU46-2.


GAL2B_DANRE Galanin receptor 2b (sprot)

A protein that is a translation product of the galr2b gene in zebrafish.


name: protocadherin gamma-B1 cysteinylated 1 (human)

description: A protocadherin gamma-B1 (human) that has been cysteinylated on the residue at the position equivalent to Cys-380 of the amino acid sequence represented by UniProtKB:Q9Y5G3-1. Example: UniProtKB:Q9Y5G3-1, Cys-380, MOD:00765.


name: phosphatidylethanolamine-binding protein 1 isoform 1 (human)

description: A phosphatidylethanolamine-binding protein 1 isoform 1 that is encoded in the genome of human.


name: YLNA_SCHPO Uncharacterized protein PB8E5.10 (sprot)

description: A protein that is a translation product of the SPAPB8E5.10 gene in Schizosaccharomyces pombe 972h-.


autophagy protein 5 isoform 1 (rat)

An autophagy protein 5 isoform 1 that is encoded in the genome of rat.


MCH_MOUSE Pro-MCH (sprot)

A pro-MCH that is encoded in the genome of mouse.


Low serum calcitriol

description: A reduced concentration of calcitriol in the blood. Calcitriol is also known as 1,25-dihydroxycholecalciferol or 1,25-dihydroxyvitamin D3.


name: Decreased circulating calcifediol concentration

description: A reduced concentration of calcifediol in the blood. Calcifediol is also known as calcidiol, 25-hydroxycholecalciferol and 25-Hydroxyvitamin D3.


name: Infant-Type Hemispheric Glioma, ROS1-Altered

description: A high-grade cellular astrocytoma that arises in the cerebral hemisphere and occurs in early childhood. It is characterized by receptor tyrosine kinase fusions in the ROS1 gene.


septin-6 phosphorylated 1 (mouse)

A septin-6 phosphorylated 1 in mouse. UniProtKB:Q9R1T4, Ser-416, MOD:00046.


name: Bcl2-associated agonist of cell death isoform 1 phosphorylated 6 (mouse)

description: A Bcl2-associated agonist of cell death isoform 1 phosphorylated 6 in mouse. UniProtKB:Q61337-1, Ser-128/Ser-136, MOD:00046.


name: heparan sulfate 2-O-sulfotransferase pipe isoform 12 (fruit fly)

description: A heparan sulfate 2-O-sulfotransferase pipe (fruit fly) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q86BJ3-12.


name: Hypopharyngeal Cancer pN1 TNM Finding v6 and v7

description: Hypopharyngeal cancer with metastasis to a single ipsilateral lymph node, 3 cm or less in greatest dimension. (from AJCC 6th and 7th Eds.)


Hypopharyngeal Cancer TNM Finding v7

description: A finding about one or more characteristics of hypopharyngeal cancer, following the rules of the TNM AJCC v7 classification system.


name: Hypopharyngeal Cancer Clinical Distant Metastasis TNM Finding v7

description: A clinical finding about one or more characteristics of hypopharyngeal cancer, following the rules of the TNM AJCC v7 classification system as they pertain to distant metastases.


name: Hypopharyngeal Cancer cM0 TNM Finding v7

description: Hypopharyngeal cancer without evidence of distant metastasis. (from AJCC 7th Ed.)


name: Hypopharyngeal Cancer pN2c TNM Finding v6 and v7

description: Hypopharyngeal cancer with metastasis in bilateral or contralateral lymph nodes, none more than 6 cm in greatest dimension. (from AJCC 6th and 7th Eds.)


name: Hypopharyngeal Cancer pTX TNM Finding v6 and v7

description: Hypopharyngeal cancer in which the primary tumor cannot be assessed. (from AJCC 6th and 7th Eds.)


name: Hypopharyngeal Cancer pT4a TNM Finding v7

description: Hypopharyngeal cancer with moderately advanced local disease.  Tumor invades the thyroid/cricoid cartilage, hyoid bone, thyroid gland, or central compartment soft tissue.  Central compartment soft tissue includes prelaryngeal strap muscles and subcutaneous fat. (from AJCC 7th Ed.)


name: Hypopharyngeal Cancer pM1 TNM Finding v6 and v7

description: Hypopharyngeal cancer with distant metastasis. (from AJCC 6th and 7th Eds.)


name: Hypopharyngeal Cancer cM1 TNM Finding v7

description: Hypopharyngeal cancer with distant metastasis. (from AJCC 7th Ed.)


name: Hypopharyngeal Cancer pT3 TNM Finding v7

description: Hypopharyngeal cancer with tumor measuring more than 4 cm in greatest dimension or with fixation of hemilarynx or extension to esophagus. (from AJCC 7th Ed.)


name: Hypopharyngeal Cancer pN2 TNM Finding v7

description: Hypopharyngeal cancer with metastasis in a single ipsilateral lymph node, more than 3 cm but not more than 6 cm in greatest dimension, or in multiple ipsilateral lymph nodes, none more than 6 cm in greatest dimension, or in bilateral or contralateral lymph nodes, none more than 6 cm in greatest dimension. (from AJCC 7th Ed.)


name: Hypopharyngeal Cancer Clinical TNM Finding v7

description: A clinical finding about one or more characteristics of hypopharyngeal cancer, following the rules of the TNM AJCC v7 classification system.


name: Hypopharyngeal Cancer Pathologic Regional Lymph Nodes TNM Finding v7

description: A pathologic finding about one or more characteristics of hypopharyngeal cancer, following the rules of the TNM AJCC v7 classification system as they pertain to staging of regional lymph nodes.  Metastases at level VII are considered regional lymph node metastases. (from AJCC 7th Ed.)


name: Hypopharyngeal Cancer pN0 TNM Finding v6 and v7

description: Hypopharyngeal cancer with no metastasis to regional lymph nodes. (from AJCC 6th and 7th Eds.)


name: Hypopharyngeal Cancer Pathologic Distant Metastasis TNM Finding v7

description: A pathologic finding about one or more characteristics of hypopharyngeal cancer, following the rules of the TNM AJCC v7 classification system as they pertain to distant metastases.  There is no pathologic M0 for hypopharyngeal cancer.


name: Hypopharyngeal Cancer pT4b TNM Finding v7

description: Hypopharyngeal cancer with very advanced local disease.  Tumor invades prevertebral fascia, encases carotid artery, or involves mediastinal structures. (from AJCC 7th Ed.)


name: Hypopharyngeal Cancer Pathologic TNM Finding v7

description: A pathologic finding about one or more characteristics of hypopharyngeal cancer, following the rules of the TNM AJCC v7 classification system.  The pathologic staging requires the use of all information obtained in clinical staging and in histologic study of the surgically resected specimens.  (from AJCC 7th Ed.)


name: Hypopharyngeal Cancer pN2a TNM Finding v6 and v7

description: Hypopharyngeal cancer with metastasis to a single ipsilateral lymph node, more than 3 cm, but not more than 6 cm in greatest dimension. (from AJCC 6th and 7th Eds.)


name: Hypopharyngeal Cancer pT0 TNM Finding v6 and v7

description: Hypopharyngeal cancer with no evidence of a primary tumor. (from AJCC 6th and 7th Eds.)


name: Hypopharyngeal Cancer Pathologic Primary Tumor TNM Finding v7

description: A pathologic finding about one or more characteristics of hypopharyngeal cancer, following the rules of the TNM AJCC v7 classification system as they pertain to staging of the primary tumor.


name: Hypopharyngeal Cancer pT2 TNM Finding v6 and v7

description: Hypopharyngeal cancer with tumor invading more than one subsite of hypopharynx or an adjacent site, or with tumor size more than 2 centimeters, but not more than 4 centimeters in greatest dimension without fixation of the hemilarynx. (from AJCC 6th and 7th Eds.)


name: Hypopharyngeal Cancer pN2b TNM Finding v6 and v7

description: Hypopharyngeal cancer with metastasis in two or more ipsilateral nodes, none more than 6 cm in greatest dimension. (from AJCC 6th and 7th Eds.)


name: Hypopharyngeal Cancer pTis TNM Finding v6 and v7

description: Hypopharyngeal cancer with a finding of carcinoma in situ. (from AJCC 6th and 7th Eds.)


name: Hypopharyngeal Cancer pN3 TNM Finding v7

description: Hypopharyngeal cancer with metastasis in a lymph node more than 6 cm in greatest dimension. (from AJCC 7th Ed.)


name: Hypopharyngeal Cancer pNX TNM Finding v6 and v7

description: Hypopharyngeal cancer in which the regional lymph nodes cannot be assessed. (from AJCC 6th and 7th Eds.)


name: Hypopharyngeal Cancer pT1 TNM Finding v7

description: Hypopharyngeal cancer with tumor limited to one subsite of hypopharynx and/or 2 cm or less in greatest dimension.  (from AJCC 7th Ed.)


Sesterviolene B

A sesterterpene that is produced by a sesterterpene synthase from Streptomyces violens


name: TBCC domain-containing protein 1 isoform h1 (human)

description: A TBCC domain-containing protein 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9NVR7-1.


name: RL141_ARATH Large ribosomal subunit protein eL14z (sprot)

description: A protein that is a translation product of the RPL14A gene in Arabidopsis thaliana.


name: cilium assembly protein DZIP1 isoform h3 (human)

description: A cilium assembly protein DZIP1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q86YF9-3.


Dermal flame figures

description: Flame-figures are composed of a central part consisting of collagen fibers and eosinophilic granules, surrounded by a histiocytic and eosinophilic infiltrate. Subsequently, eosinophils tend to disappear and are replaced by phagocytic granulomas, consisting of histiocytes and sometimes giant cells, around the flame figures.


name: YCBK_ECOLI Uncharacterized protein YcbK (sprot)

description: An uncharacterized protein YcbK that is encoded in the genome of Escherichia coli K-12.


name: Type 2 Diabetes Mellitus with Moderate Nonproliferative Diabetic Retinopathy without Macular Edema, Unspecified Eye

description: Evidence of type 2 diabetes mellitus with moderate nonproliferative diabetic retinopathy without macular edema in an unspecified eye.


name: Acute duodenal ulcer without hemorrhage AND without perforation

description: Evidence of an acute duodenal ulcer without hemorrhage or perforation.


protein LRATD1 isoform 1

A protein LRATD1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q96KN4-1 or a 1:1 ortholog thereof.


protein LRATD1 isoform 1 (human)

A protein LRATD1 isoform 1 that is encoded in the genome of human.


protein FAM84A isoform 1 (mouse)

A protein LRATD1 isoform 1 that is encoded in the genome of mouse.


name: IQM6_ARATH IQ domain-containing protein IQM6 (sprot)

description: A protein that is a translation product of the IQM6 gene in Arabidopsis thaliana.


name: junctional adhesion molecule C isoform 1 (rat)

description: A junctional adhesion molecule C isoform 1 that is encoded in the genome of rat.


name: Argentaffin Positive Neoplastic Cells Present


name: ephrin type-A receptor 7 isoform 1 (chicken)

description: An ephrin type-A receptor 7 isoform 2 that is encoded in the genome of chicken.


name: EPHA7_CHICK Ephrin type-A receptor 7 (sprot)

description: An ephrin type-A receptor 7 that is encoded in the genome of chicken.


name: Grade 5 Intraoperative Ear Injury, CTCAE

description: Death


Intraoperative Ear Injury, CTCAE

description: A finding of damage to the ear during a surgical procedure.


name: Grade 2 Intraoperative Ear Injury, CTCAE

description: Partial resection of injured organ/structure indicated


name: Grade 3 Intraoperative Ear Injury, CTCAE

description: Complete resection or reconstruction of injured organ/structure indicated; limiting self care ADL (e.g., impaired hearing; impaired balance)


name: Grade 4 Intraoperative Ear Injury, CTCAE

description: Life-threatening consequences; urgent intervention indicated


name: Grade 1 Intraoperative Ear Injury, CTCAE

description: Primary repair of injured organ/structure indicated


An inorganic anion that is a polyboron cluster made up from twelve boron atoms with a net charge of -2.


name: FSH-Producing Pituitary Neuroendocrine Tumor

description: A pituitary neuroendocrine tumor that produces follicle-stimulating hormone (FSH).


Anterior Pituitary Gland Neoplasm

description: A neoplasm arising from the anterior lobe of the pituitary gland. The vast majority are pituitary neuroendocrine tumors (formerly pituitary adenomas).


name: Immature PIT1 Lineage Pituitary Neuroendocrine Tumor

description: An immature pituitary neuroendocrine tumor composed of PIT1-lineage adenohypophyseal cells with cytologic atypia and limited differentiation towards thyrotroph, somatotroph, and/or lactotroph cells. (WHO)


name: Pituitary Neuroendocrine Tumor without Distinct Lineage Differentiation

description: A pituitary neuroendocrine tumor that belongs to more than one adenohypophysial cell lineage or does not show evidence of adenohypophysial hormonal immunoreactivity and specific adenohypophysial cell derivation.


name: Locally Advanced Pituitary Neuroendocrine Tumor

description: Pituitary neuroendocrine tumor that has spread from its original site of growth to nearby tissues or lymph nodes.


name: Somatotroph-Lactotroph Pituitary Neuroendocrine Tumor

description: A pituitary neuroendocrine tumor that produces both growth hormone and prolactin.


name: Pituitary Neuroendocrine Tumor of PIT1-Lineage

description: A pituitary neuroendocrine tumor arising from PIT1-lineage adenohypophysial cells.


pituitary gland adenoma

description: A non-metastasizing tumor that arises from the adenohypophysial cells of the anterior lobe of the pituitary gland. The tumor can be hormonally functioning or not. The diagnosis can be based on imaging studies and/or radioimmunoassays. Due to its location in the sella turcica, expansion of the tumor mass can impinge on the optic chiasm or involve the temporal lobe, third ventricle and posterior fossa A frequently associated physical finding is bitemporal hemianopsia which may progress to further visual loss.


name: Densely Granulated Corticotroph Pituitary Neuroendocrine Tumor

description: A corticotroph pituitary neuroendocrine tumor composed of basophilic PAS-positive cells that are diffusely and strongly positive for ACTH, consistent with the abundance of secretory granules seen at the ultrastructural level. (WHO)


name: Pituitary Neuroendocrine Tumor of SF1-Lineage

description: A pituitary neuroendocrine tumor arising from SF1-lineage adenohypophysial cells.


name: Pituitary Neuroendocrine Tumor, Not Otherwise Specified

description: A pituitary neuroendocrine tumor in which further characterization regarding subtyping is not available.


Crooke Cell Tumor

description: A corticotroph pituitary tumor composed of cells with Crooke hyaline change. Ring-like cytokeratin expression is typical of these neoplasms. ACTH expression is dislocated to the cell periphery and juxtanuclear region. Ultrastructurally, intermediate filaments are arranged in a ring-like pattern. (WHO)


name: Mammosomatotroph Pituitary Neuroendocrine Tumor

description: A pituitary neuroendocrine tumor composed of acidophilic cells that produce both growth hormone and prolactin. Immunohistochemical studies reveal the presence of these two hormones localized in the same cell.


name: Null Cell Pituitary Neuroendocrine Tumor

description: A non-functioning pituitary neuroendocrine tumor without hormonal immunoreactivity or evidence of specific adenohypophyseal cell derivation.


name: LH-Producing Pituitary Neuroendocrine Tumor

description: A pituitary neuroendocrine tumor that produces luteinizing hormone (LH).


non-functioning pituitary adenoma

description: A hormone producing or non-producing pituitary gland adenoma not associated with a hormonal syndrome.


Pituitary macroadenoma

description: A pituitary gland adenoma that is larger than 10mm.


name: Plurimorphous Plurihormonal Pituitary Neuroendocrine Tumor

description: A plurihormonal pituitary neuroendocrine tumor consisting of two or more different cell lineages. (WHO)


name: Non-Functioning Densely Granulated Corticotroph Pituitary Neuroendocrine Tumor

description: A densely granulated corticotroph pituitary neuroendocrine tumor not associated with a hormonal syndrome.


name: ACTH-producing pituitary gland carcinoma

description: A rare, hormonally functioning or non-functioning pituitary gland adenocarcinoma that produces corticotropin. It may be associated with Cushing disease.


name: Non-Functioning Pituitary Neuroendocrine Tumor/Macroadenoma

description: A pituitary neuroendocrine tumor/macroadenoma not associated with a hormonal syndrome.


pituitary blastoma

description: A pituitary cancer that is characterized by features of Cushing disease, with elevated blood ACTH levels and hypercortisolism arising within the fetal anterior pituitary and associated with DICER1 mutations.


name: mixed somatotroph-lactotroph pituitary gland adenoma

description: An infrequent pituitary gland adenoma composed of an admixture of acidophilic and chromophobic cells that produce growth hormone and prolactin respectively. Unlike mammosomatotroph adenomas, these two hormones are not localized in the same cell by immunohistochemistry.


name: Functioning Pituitary Neuroendocrine Tumor/Macroadenoma

description: A pituitary neuroendocrine tumor/macroadenoma associated with a hormonal syndrome.


name: Functioning Pituitary Neuroendocrine Tumor/Microadenoma

description: A pituitary neuroendocrine tumor/microadenoma associated with a hormonal syndrome.


name: Recurrent Anterior Pituitary Gland Neoplasm

description: The reemergence of a pituitary gland neoplasm after a period of remission.


pituitary adenocarcinoma

description: A rare adenocarcinoma with poor prognosis, arising from the adenohypophysial cells of the anterior lobe of the pituitary gland or pre-existing adenomas. The majority are hormonally functioning neoplasms, usually producing prolactin or ACTH. The diagnosis is based on the presence of metastases. Syndromes associated with pituitary gland carcinomas include hyperprolactinemia, Cushing disease, and acromegaly.


name: Double Pituitary Neuroendocrine Tumors of Distinct Lineages

description: Pituitary neuroendocrine tumors composed of adenohypopheseal cells of two lineages or a null cell tumor in combination with a lineage-specific pituitary neuroendocrine tumor in the same gland.


name: Non-Functioning Corticotroph Pituitary Neuroendocrine Tumor

description: Corticotroph pituitary neuroendocrine tumor not associated with a hormonal syndrome.


name: prolactin-producing pituitary gland carcinoma

description: A rare, hormonally functioning or non-functioning pituitary gland adenocarcinoma that produces prolactin.


name: growth hormone-producing pituitary gland carcinoma

description: A rare, hormonally functioning or non-functioning pituitary gland adenocarcinoma that produces growth hormone. It may be associated with acromegaly.


name: Monomorphous Plurihormonal Pituitary Neuroendocrine Tumor

description: A plurihormonal pituitary neuroendocrine tumor consisting of a single cell type producing two (or rarely more) hormones. (WHO)


Ectopic Pituitary Neuroendocrine Tumor

description: A pituitary neuroendocrine tumor that does not involve the sella turcica.


name: Acidophil Stem Cell Pituitary Neuroendocrine Tumor

description: An infrequent pituitary neuroendocrine tumor composed of cells showing immunoreactivity for prolactin and less often growth hormone. Electron microscopic studies reveal giant mitochondria, a finding not present in any other type of pituitary gland adenomas.


ACTH-producing pituitary gland adenoma

description: An adenoma of the pituitary gland that produces corticotropin. The vast majority of cases are associated with Cushing disease. Clinical manifestations include truncal obesity with thin extremities, thinning of the skin, osteoporosis, and a tendency to bruise easily. Silent or hormonally non-functioning ACTH producing adenomas have also been described. They produce symptoms of a mass-related lesion.


name: Non-Functioning Pituitary Neuroendocrine Tumor/Microadenoma

description: A pituitary neuroendocrine tumor/microadenoma not associated with a hormonal syndrome.


name: Pituitary Neuroendocrine Tumor of TPIT-Lineage

description: A pituitary neuroendocrine tumor arising from TPIT-lineage adenohypophysial cells.


name: Sparsely Granulated Somatotroph Pituitary Neuroendocrine Tumor

description: A growth hormone-producing pituitary neuroendocrine tumor composed of small, round cells containing fibrous bodies and scarce, small secretory granules.


name: Densely Granulated Lactotroph Pituitary Neuroendocrine Tumor

description: A rare prolactin-producing pituitary neuroendocrine tumor composed of acidophilic cells with many large secretory granules.  The endoplasmic reticulum is not as abundant as in the sparsely granulated subtype.


name: Sparsely Granulated Lactotroph Pituitary Neuroendocrine Tumor

description: A prolactin-producing pituitary neuroendocrine tumor composed of relatively large, chromophobic or slightly acidophilic cells with well developed, abundant endoplasmic reticulum, and many immature secretory granules.  Mature secretory granules are sparse.


name: Metastatic Unresectable Pituitary Neuroendocrine Tumor

description: Metastatic pituitary neuroendocrine tumor that is not amenable to surgical resection.


name: Plurihormonal Pituitary Neuroendocrine Tumor

description: A pituitary neuroendocrine tumor that expresses adenohypophyseal hormones and belongs to more than one adenohypophysial cell lineage.


name: Mature Plurihormonal PIT1 Lineage Pituitary Neuroendocrine Tumor

description: A well-differentiated pituitary neuroendocrine tumor composed of PIT1-lineage adenohypophyseal cells with acidophilic cytoplasm, extensive immunoreactivity for growth hormone and variable immunoreactivity for TSH, prolactin, and alpha-subunit. (WHO)


name: Sparsely Granulated Corticotroph Pituitary Neuroendocrine Tumor

description: A corticotroph pituitary neuroendocrine tumor composed of faintly basophilic or chromophobic PAS-positive cells with weak or patchy positivity for ACTH, consistent with the scant, small secretory granules seen ultrastructurally. (WHO)


Atypical Pituitary Neuroendocrine Tumor

description: A usually aggressive and invasive pituitary neuroendocrine tumor characterized by excessive p53 immunoreactivity, increased mitotic activity, and MIB-1 proliferative index greater than 3%.


name: Densely Granulated Somatotroph Pituitary Neuroendocrine Tumor

description: A growth hormone-producing pituitary neuroendocrine tumor composed of medium-sized acidophilic cells with granular cytoplasm and abundant secretory granules.


description: A pituitary neuroendocrine tumor with a diameter equal or less than 10 mm.


name: Multiple Synchronous Pituitary Neuroendocrine Tumors of Distinct Lineages

description: Multiple pituitary neuroendocrine tumors composed of adenohypopheseal cells of two or more lineages or a null cell tumor in combination with a lineage-specific pituitary neuroendocrine tumor in the same gland.


name: Non-Functioning Sparsely Granulated Corticotroph Pituitary Neuroendocrine Tumor

description: A sparsely granulated corticotroph pituitary neuroendocrine tumor not associated with a hormonal syndrome.


name: Nasopharyngeal Pituitary Neuroendocrine Tumor

description: An ectopic pituitary neuroendocrine tumor that arises from the nasopharynx.


name: Mixed Gangliocytoma-Pituitary Neuroendocrine Tumor

description: A pituitary neoplasm composed of mature ganglionic cells admixed with pituitary neoplastic neuroendocrine cells.


name: ATP-binding cassette sub-family G member 1 isoform 4 (human)

description: An ATP-binding cassette sub-family G member 1 isoform 4 that is encoded in the genome of human.


name: ubiquitin-like domain-containing CTD phosphatase 1 isoform 1 (rat)

description: A ubiquitin-like domain-containing CTD phosphatase 1 isoform 1 that is encoded in the genome of rat.


name: ubiquitin-like domain-containing CTD phosphatase 1

description: A protein that is a translation product of the human UBLCP1 gene or a 1:1 ortholog thereof.


name: ubiquitin-like domain-containing CTD phosphatase 1 isoform 1 (human)

description: A ubiquitin-like domain-containing CTD phosphatase 1 isoform 1 that is encoded in the genome of human.


name: ubiquitin-like domain-containing CTD phosphatase 1 isoform m2 (mouse)

description: A ubiquitin-like domain-containing CTD phosphatase 1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8BGR9-2.


name: UBCP1_CHICK Ubiquitin-like domain-containing CTD phosphatase 1 (sprot)

description: A ubiquitin-like domain-containing CTD phosphatase 1 that is encoded in the genome of chicken.


name: UBCP1_DROME Ubiquitin-like domain-containing CTD phosphatase 1 (sprot)

description: A ubiquitin-like domain-containing CTD phosphatase 1 that is encoded in the genome of fruit fly.


name: UBCP1_HUMAN Ubiquitin-like domain-containing CTD phosphatase 1 (sprot)

description: A ubiquitin-like domain-containing CTD phosphatase 1 that is encoded in the genome of human.


name: ubiquitin-like domain-containing CTD phosphatase 1 isoform 1

description: A ubiquitin-like domain-containing CTD phosphatase 1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8WVY7-1 or a 1:1 ortholog thereof.


name: ubiquitin-like domain-containing CTD phosphatase 1 isoform 1 (mouse)

description: A ubiquitin-like domain-containing CTD phosphatase 1 isoform 1 that is encoded in the genome of mouse.


name: UBCP1_MOUSE Ubiquitin-like domain-containing CTD phosphatase 1 (sprot)

description: A ubiquitin-like domain-containing CTD phosphatase 1 that is encoded in the genome of mouse.


name: UBCP1_RAT Ubiquitin-like domain-containing CTD phosphatase 1 (sprot)

description: A ubiquitin-like domain-containing CTD phosphatase 1 that is encoded in the genome of rat.


name: ubiquitin-like domain-containing CTD phosphatase 1, initiator methionine removed form

description: A ubiquitin-like domain-containing CTD phosphatase 1 that has had the initiator methionine removed.


name: UBCP_ARATH Ubiquitin-like domain-containing CTD phosphatase (sprot)

description: A ubiquitin-like domain-containing CTD phosphatase 1 that is encoded in the genome of Arabidopsis thaliana.


name: ubiquitin-like domain-containing CTD phosphatase 1 isoform 1 (zebrafish)

description: A ubiquitin-like domain-containing CTD phosphatase 1 isoform 1 that is encoded in the genome of zebrafish.


name: ubiquitin-like domain-containing CTD phosphatase 1 isoform 1 (chicken)

description: A ubiquitin-like domain-containing CTD phosphatase 1 isoform 1 that is encoded in the genome of chicken.


name: THAP4_RAT Peroxynitrite isomerase THAP4 (sprot)

description: A peroxynitrite isomerase THAP4 that is encoded in the genome of rat.


name: receptor-type tyrosine-protein phosphatase dep-1 isoform a (worm)

description: A receptor-type tyrosine-protein phosphatase dep-1 (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:G5EGJ9-1.


tetraspanin-1 N-glycosylated 1 (human)

A tetraspanin-1 (human) that has been N-glycosylated at the residue equivalent to Asn-154 of the amino acid sequence represented by UniProtKB:O60635-1, in which the glycan composition is represented by GlyTouCan:G01650EU. Example: UniProtKB:O60635-1, Asn-154, MOD:00160~GNO:G01650EU.


TSN1_HUMAN Tetraspanin-1 (sprot)

A tetraspanin-1 that is encoded in the genome of human.


tetraspanin-1 isoform 1 (human)

A tetraspanin-1 isoform 1 that is encoded in the genome of human.


name: EI3EB_DANRE Eukaryotic translation initiation factor 3 subunit E-B (sprot)

description: A eukaryotic translation initiation factor 3 subunit E that is encoded in the genome of zebrafish.


name: eukaryotic translation initiation factor 3 subunit E-B isoform 2 (zebrafish)

description: A eukaryotic translation initiation factor 3 subunit E-B (zebrafish) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q1LUA8-2.


name: eukaryotic translation initiation factor 3 subunit E-B isoform 1 (zebrafish)

description: A eukaryotic translation initiation factor 3 subunit E-B (zebrafish) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q1LUA8-1.


name: follitropin subunit beta N-glycosylated 5 (human)

description: A follitropin subunit beta (human) that has been N-glycosylated at the residue equivalent to Asn-42 of the amino acid sequence represented by UniProtKB:P01225-1, in which the glycan structure is represented by GlyTouCan:G05850WN. Example: UniProtKB:P01225-1, Asn-42, MOD:00160~GNO:G05850WN.


name: unexplained long-lasting fever/inflammatory syndrome


Rectocele

description: A Rectocele results from a tear in the rectovaginal septum (which is normally a tough, fibrous, sheet-like divider between the rectum and vagina). Rectal tissue bulges through this tear and into the vagina as a hernia. There are two main causes of this tear: childbirth, and hysterectomy.


name: vitamin K epoxide reductase complex subunit 1 isoform 1 (mouse)

description: A vitamin K epoxide reductase complex subunit 1 isoform 1 that is encoded in the genome of mouse.


name: LHX3_CHICK LIM/homeobox protein Lhx3 (sprot)

description: A LIM/homeobox protein Lhx3 that is encoded in the genome of chicken.


RHAA_ECOLI L-rhamnose isomerase (sprot)

An L-rhamnose isomerase that is encoded in the genome of Escherichia coli K-12.


L-rhamnose isomerase

A protein that is a translation product of the Escherichia coli K-12 rhaA gene or a 1:1 ortholog thereof.


name: transcription factor 7-like 2 isoform 1 (mouse)

description: A transcription factor 7-like 2 isoform 1 that is encoded in the genome of mouse.


name: tRNA (cytosine(38)-C(5))-methyltransferase isoform E (human)

description: A tRNA (cytosine(38)-C(5))-methyltransferase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O14717-5.


name: RHCL2_DANRE Ammonium transporter Rh type C-like 2 (sprot)

description: An ammonium transporter Rh type C that is encoded in the genome of zebrafish.


TMOD4_MOUSE Tropomodulin-4 (sprot)

A tropomodulin-4 that is encoded in the genome of mouse.


A protein that is a translation product of the human TMOD4 gene or a 1:1 ortholog thereof.


tropomodulin-4 isoform h2 (human)

A tropomodulin-4 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9NZQ9-2.


tropomodulin-4 isoform 1 (mouse)

A tropomodulin-4 isoform 1 that is encoded in the genome of mouse.


tropomodulin-4 isoform 1

A tropomodulin-4 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9NZQ9-1 or a 1:1 ortholog thereof.


TMOD4_HUMAN Tropomodulin-4 (sprot)

A tropomodulin-4 that is encoded in the genome of human.


tropomodulin-4 isoform 1 (human)

A tropomodulin-4 isoform 1 that is encoded in the genome of human.


name: polyglutamine-repeat protein pqn-41 isoform c (worm)

description: A polyglutamine-repeat protein pqn-41 (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:C7IVR4-3.


A steroid acid, the 4-carboxy derivative of zymosterol.


name: Fractured proximal epiphysis of first metacarpal bone

description: A partial or complete breakage of the proximal epiphysis of first metacarpal bone.


yadanziolide T

A quassinoid that is picras-3-ene substituted by hydroxy groups at positions 1, 11, 12, 15 and 21 and oxo groups at positions 2 and 16. Isolated from the ethanol extract of the stem of Brucea mollis, it exhibits cytotoxic activity.


An aromatic ether, being the (2R)-3-(tert-butylamino)-2-hydroxypropyl ether of the phenolic hydroxy group of (6S,7R)-5,6,7,8-tetrahydronaphthalene-1,6,7-triol.


Advanced Extramammary Paget Disease

description: Extramammary Paget disease that has spread extensively to other anatomic sites or is no longer responding to treatment.


extramammary Paget disease

description: A malignant neoplasm in which there is infiltration of the skin by neoplastic large cells with abundant pale cytoplasm and large nuclei with prominent nucleoli (Paget cells). It may affect the anus, penis, scrotum, and vulva.


vulval Paget disease

description: An uncommon intraepithelial malignant neoplasm of eccrine or apocrine origin, arising from the vulva. It usually affects post-menopausal women. In approximately 10-20% of the cases there is an associated anorectal, or urothelial carcinoma or a skin appendage adenocarcinoma identified. It presents as a red, eczematous lesion. Microscopically, it is characterized by the presence of the typical Paget cells which are large, round cells with abundant cytoplasm and prominent nuclei.


scrotum Paget disease

description: A mammary Paget's disease that involves the scrotum.


name: Recurrent Paget Disease of the Anal Canal

description: The reemergence of Paget disease of the anal canal after a period of remission.


Recurrent Extramammary Paget Disease

description: The reemergence of extramammary Paget disease after a period of remission.


Metastatic Extramammary Paget Disease

description: Extramammary Paget disease that has spread from the original site of growth to other anatomic sites.


Paget disease of the penis

description: A premalignant condition morphologically characterized by the presence of the characteristic Paget cells in the intraepithelial tissue of the penis. It presents as a smooth raised reddish area that may or may not be painful. -- 2003


Refractory Extramammary Paget Disease

description: Extramammary Paget disease that is resistant to treatment.


name: sorbin and SH3 domain-containing protein 2 isoform m6 (mouse)

description: A sorbin and SH3 domain-containing protein 2 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q3UTJ2-6.


name: DnaJ homolog subfamily A member 1 cysteinylated 2 (human)

description: A DnaJ homolog subfamily A member 1 (human) that has been cysteinylated on the residue at the position equivalent to Cys-177 of the amino acid sequence represented by UniProtKB:P31689-1. Example: UniProtKB:P31689-1, Cys-177, MOD:00765.


cullin-4A isoform h2 (human)

A cullin-4A (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q13619-2.


name: KSYK_HUMAN Tyrosine-protein kinase SYK (sprot)

description: A tyrosine-protein kinase SYK that is encoded in the genome of human.


name: tyrosine-protein kinase SYK cysteinylated 1 (human)

description: A tyrosine-protein kinase SYK (human) that has been cysteinylated on the residue at the position equivalent to Cys-608 of the amino acid sequence represented by UniProtKB:P43405-1. Example: UniProtKB:P43405-1, Cys-608, MOD:00765.


name: tyrosine-protein kinase SYK isoform Short (human)

description: A tyrosine-protein kinase SYK (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P43405-2.


name: tyrosine-protein kinase SYK deaminated 1 (human)

description: A tyrosine-protein kinase SYK (human) that has been deaminated on the residue at the position equivalent to Asn-499 of the amino acid sequence represented by UniProtKB:P43405-1. Example: UniProtKB:P43405-1, Asn-499, MOD:00684.


name: tyrosine-protein kinase SYK phosphotyrosine form (human)

description: A tyrosine-protein kinase SYK (human) that includes at least one phosphorylated tyrosine. UniProtKB:P43405, MOD:00048.


name: tyrosine-protein kinase SYK phosphorylated 2 (human)

description: A tyrosine-protein kinase SYK phosphorylated 2 in human. UniProtKB:P43405, Tyr-348, MOD:00048.


name: tyrosine-protein kinase SYK phosphorylated 3 (human)

description: A tyrosine-protein kinase SYK (human) that has been post-translationally modified to include phosphotyrosine at positions 131, 323, 348, 352, 525 and 526 of the amino acid sequence represented by UniProtKB:P43405. UniProtKB:P43405, Tyr-131/Tyr-323/Tyr-348/Tyr-352/Tyr-525/Tyr-526, MOD:00048.


name: collagen alpha-1(XXIII) chain 4-hydroxy-proline and galactosylhydroxylysine form (human)

description: A collagen alpha-1(XXIII) chain (human) that includes at least 1 galactosylhydroxylated lysine and at least 3 4-hydroxy-prolines. UniProtKB:Q86Y22, MOD:00039(3+)|MOD:01914.


name: mitogen-activated protein kinase kinase kinase 20 methylated 2 (human)

description: A mitogen-activated protein kinase kinase kinase 20 (human) that has been methylated on the residue at the position equivalent to Arg-670 of the amino acid sequence represented by UniProtKB:Q9NYL2-1. Example: UniProtKB:Q9NYL2-1, Arg-670, MOD:00658.


name: chorion-specific transcription factor GCMa isoform 1

description: A chorion-specific transcription factor GCMa that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9NP62-1 or a 1:1 ortholog thereof.


name: chorion-specific transcription factor GCMa

description: A protein that is a translation product of the human GCM1 gene or a 1:1 ortholog thereof.


name: chorion-specific transcription factor GCMa acetylated 1

description: A chorion-specific transcription factor GCMa that has been acetylated in Lys residues within the C-terminal region. Example: UniProtKB:P70348, Lys-367/Lys-406, MOD:00064.


name: chorion-specific transcription factor GCMa acetylated 1 (mouse)

description: A chorion-specific transcription factor GCMa acetylated 1 in mouse. UniProtKB:P70348, Lys-367/Lys-406, MOD:00064.


name: chorion-specific transcription factor GCMa isoform 1 (human)

description: A chorion-specific transcription factor GCMa isoform 1 that is encoded in the genome of human.


name: GCM1_HUMAN Chorion-specific transcription factor GCMa (sprot)

description: A chorion-specific transcription factor GCMa that is encoded in the genome of human.


name: GCM1_RAT Chorion-specific transcription factor GCMa (sprot)

description: A chorion-specific transcription factor GCMa that is encoded in the genome of rat.


name: GCM1_MOUSE Chorion-specific transcription factor GCMa (sprot)

description: A chorion-specific transcription factor GCMa that is encoded in the genome of mouse.


name: chorion-specific transcription factor GCMa isoform 1 acetylated 1

description: A chorion-specific transcription factor GCMa isoform 1 that has been acetylated on Lys residues located within the transactivation domain (TAD) towards the C-terminus. Example: UniProtKB:Q9NP62-1, Lys-367/Lys-406/Lys-409, MOD:00064.


name: chorion-specific transcription factor GCMa isoform 1 acetylated 1 (human)

description: A chorion-specific transcription factor GCMa isoform 1 acetylated 1 in human. UniProtKB:Q9NP62-1, Lys-367/Lys-406/Lys-409, MOD:00064.


name: TDCR_ECOLI Threonine dehydratase operon activator protein (sprot)

description: A threonine dehydratase operon activator protein that is encoded in the genome of Escherichia coli K-12.


name: bromodomain adjacent to zinc finger domain protein 2B deaminated 2 (human)

description: A bromodomain adjacent to zinc finger domain protein 2B (human) that has been deaminated on the residue at the position equivalent to Gln-499 of the amino acid sequence represented by UniProtKB:Q9UIF8-1. Example: UniProtKB:Q9UIF8-1, Gln-499, MOD:00685.


name: bromodomain adjacent to zinc finger domain protein 2B

description: A protein that is a translation product of the human BAZ2B gene or a 1:1 ortholog thereof.


name: BAZ2B_MOUSE Bromodomain adjacent to zinc finger domain protein 2B (sprot)

description: A bromodomain adjacent to zinc finger domain protein 2B that is encoded in the genome of mouse.


name: bromodomain adjacent to zinc finger domain protein 2B isoform h5 (human)

description: A bromodomain adjacent to zinc finger domain protein 2B (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9UIF8-5.


name: bromodomain adjacent to zinc finger domain protein 2B isoform h2 (human)

description: A bromodomain adjacent to zinc finger domain protein 2B (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9UIF8-2.


name: bromodomain adjacent to zinc finger domain protein 2B isoform m2 (mouse)

description: A bromodomain adjacent to zinc finger domain protein 2B (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:A2AUY4-2.