name: Other Psychoactive Substance Abuse with Withdrawal with Perceptual Disturbance

description: Evidence of other psychoactive substance abuse with withdrawal with perceptual disturbance not specified elsewhere.


name: Hallucinogen Use, Unspecified with Hallucinogen-Induced Psychotic Disorder with Delusions

category: biolink:Disease biolink:DiseaseOrPhenotypicFeature biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing

description: Evidence of hallucinogen use, unspecified with hallucinogen-induced psychotic disorder with delusions.


name: Monoplegia of Upper Limb following Non-Traumatic Subarachnoid Hemorrhage Affecting Left Dominant Side

description: Evidence of monoplegia of upper limb following non-traumatic subarachnoid hemorrhage affecting left dominant side.


Grade 1 Pelvis Pain, CTCAE

category: biolink:PhenotypicFeature biolink:DiseaseOrPhenotypicFeature biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing


Grade 3 Floaters, CTCAE

description: Limiting self care ADL


carcinoma of urinary tract

description: A carcinoma that arises from the organs that comprise the urinary tract. This category includes renal pelvis carcinoma, ureter carcinoma, bladder carcinoma, urethral carcinoma, urothelial carcinoma, adenocarcinoma of the urinary tract, clear cell adenocarcinoma of the urinary tract, diverticular carcinoma of the urinary tract, endometrioid adenocarcinoma of the urinary tract, and squamous cell carcinoma of the urinary tract.


name: Grade 4 Peritoneal Cavity Infection with Unknown Absolute Neutrophil Count, CTCAE


name: Grade 3 Lymphatic Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


Squamous cell carcinoma, microinvasive

description: A squamous cell carcinoma with minimal stromal invasion.


name: Childhood Retinoblastoma by Toronto Guidelines v2 Stage, Tier 2

description: A term that refers to the staging of childhood retinoblastoma according to the tier 2 Toronto childhood cancer staging guidelines v2.


name: Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8

description: Stage III includes: (T2, N1, M0); (T3, N0-1, M0); (T4a, N0-1, M0). T2: Tumor invades the muscularis propria. T3: Tumor invades adventitia. T4a: Tumor invades the pleura, pericardium, azygos vein, diaphragm, or peritoneum N0: No regional lymph node metastasis. N1: Tumor with metastasis in one or two regional lymph nodes. M0: No distant metastasis. (AJCC 8th ed.)


name: Cornea Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


Pharyngeal Cancer TNM Finding v8

description: A finding about one or more characteristics of pharyngeal cancer, following the rules of the TNM AJCC v8 classification system. (from AJCC 8th Ed.)


name: Type 2 Diabetes Mellitus with Unspecified Diabetic Retinopathy without Macular Edema

description: Evidence of type 2 diabetes mellitus with unspecified diabetic retinopathy without macular edema.


name: Other Classic Hodgkin Lymphoma, Intra-abdominal Lymph Nodes

description: Evidence of other classic Hodgkin lymphoma in the intra-abdominal lymph nodes not specified elsewhere.


Cutaneous Melanoma cN1c TNM Finding v8

description: Cutaneous melanoma with no regional lymph node disease. Presence of in-transit, satellite, and/or microsatellite metastases: Yes. (from AJCC 8th Ed.)


name: Postneoadjuvant Therapy Stage IIIA Gastroesophageal Junction Adenocarcinoma AJCC v8

description: Stage IIIA includes: T0-2, N1, M0. T0: No evidence of primary tumor. T1: Tumor invades the lamina propria, muscularis mucosae, or submucosa. T2: Tumor invades the muscularis propria. N1: Tumor with metastasis in one or two regional lymph nodes. M0: No distant metastasis. (AJCC 8th ed.)


Grade 4 Duodenal Perforation, CTCAE

description: Life-threatening consequences; urgent operative intervention indicated


Autosomal Dominant Disorder

description: An inherited disorder that manifests when one copy of a mutated gene is present.


name: Grade 3 Meninges Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


name: Grade 2 Vagina Intra-Operative Injury, CTCAE


name: Conjunctival Melanoma cT3d TNM Finding v8

description: Conjunctival melanoma with tumor of any size invading the nasolacrimal duct and/or lacrimal sac and/or paranasal sinuses. (from AJCC 8th Ed.)


name: Attention and Concentration Deficit following Unspecified Cerebrovascular Disease

description: Evidence of attention and concentration deficit following unspecified cerebrovascular disease.


name: Type 1 Diabetes Mellitus with Other Skin Ulcer

description: Evidence of type 1 diabetes mellitus with other skin ulcer.


name: Nasal Cavity and Ethmoid Sinus Cancer pT4a TNM Finding v7

description: Nasal cavity and ethmoid sinus cancer with moderately advanced local disease. Tumor invades any of the following: anterior orbital contents, skin of nose or cheek, minimal extension to anterior cranial fossa, pterygoid plates, sphenoid or frontal sinuses. (from AJCC 7th Ed.)


name: Lower Extremity Intra-Operative Injury, CTCAE


name: Monoplegia of Upper Limb following Unspecified Cerebrovascular Disease Affecting Unspecified Side

description: Evidence of monoplegia of upper limb following unspecified cerebrovascular disease affecting unspecified side.


Enteropathic arthritis

description: A form of chronic arthritis that is found in some patients with inflammatory bowel disease.


name: Rheumatoid Heart Disease with Rheumatoid Arthritis of Unspecified Hand

description: Evidence of rheumatoid heart disease with rheumatoid arthritis of unspecified hand.


Grade 3 Dry Eye, CTCAE

description: Symptomatic with marked decrease in visual acuity (best corrected visual acuity worse than 20/40 or more than 3 lines of decreased vision from known baseline, up to 20/200); limiting self care ADL


name: Grade 5 Small Intestinal Obstruction, CTCAE

description: Death


name: Grade 5 Pleura Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


Cervical Cancer by FIGO Stage 2018

description: A term that refers to the staging of cervical cancer according to the International Federation of Gynecology and Obstetrics (FIGO) staging, 2018.


name: spondylopathy in diseases classified elsewhere in cervicothoracic region

description: Evidence of spondylopathy in diseases classified elsewhere in the cervicothoracic region.


Scalp Pain, CTCAE 5.0

description: A disorder characterized by a sensation of marked discomfort in the skin covering the top and the back of the head.


name: Cutaneous Melanoma cM1c(1) TNM Finding v8

description: Cutaneous melanoma with distant metastasis to non-CNS visceral sites with or without M1a or M1b sites of disease.  LDH level elevated. (from AJCC 8th Ed.)


name: Grade 5 Small Bowel Perforation NOS, CTCAE


name: Grade 5 Foreign Body Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


name: Unspecified Pre-Existing Hypertension Complicating the Puerperium

description: Evidence of unspecified pre-existing hypertension complicating the puerperium.


AIDS-Related Malignant Anal Neoplasm

description: A malignant neoplasm arising from the anus and occurring in HIV-positive patients.  Representative examples include squamous cell carcinoma and non-Hodgkin lymphoma.  Homosexual HIV-positive men have an increased risk of developing such malignancies in comparison to the general male population.


description: Evidence of cocaine dependence with cocaine-induced sexual dysfunction.


Testicular Hemorrhage, CTCAE

description: A disorder characterized by bleeding from the testis.


Hyperthyroidism, CTCAE

description: A disorder characterized by excessive levels of thyroid hormone in the body. Common causes include an overactive thyroid gland or thyroid hormone overdose.


name: Grade 5 Pelvis Infection NOS with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


Grade 1 Hypertension, CTCAE

description: Adult: Systolic BP 120-139 mm Hg or diastolic BP 80-89 mm Hg; Pediatric: Systolic/diastolic BP >90th percentile but< 95th percentile; Adolescent: BP >= 120/80 even if < 95th percentile


Grade 2 Photophobia, CTCAE

description: Limiting instrumental ADL


Refractory Malignant Endocrine Neoplasm

description: Malignant endocrine neoplasm that is resistant to treatment.


name: Nodular Sclerosis Classic Hodgkin Lymphoma, Spleen

description: Evidence of nodular sclerosis classic Hodgkin lymphoma in the spleen.


Nutritional Rickets

description: Rickets due to dietary deficiency of calcium, phosphate, or vitamin D.


name: Refractory Post-Essential Thrombocythemia Myelofibrosis

description: Post-essential thrombocythemia myelofibrosis that is resistant to treatment.


name: Occupational Paint Baking Smoke Exposure

description: Occupational exposure to airborne gases and particulates during the operation of a paint oven.


name: Unspecified Type of Carcinoma in Situ of Left Breast

description: Evidence of unspecified type of carcinoma in situ of left breast.


name: Pancreas Infection with Unknown Absolute Neutrophil Count, CTCAE


Adenocarcinoma with metaplasia

description: An adenocarcinoma characterized by the presence of metaplasia.


name: Post-Immunization Arthropathy, Unspecified Elbow

description: Evidence of post-immunization arthropathy in an unspecified elbow.


Testis cancer recurrent

description: Malignant testicular germ cell tumor reemerging after a period of remission.


name: Grade 2 Liver Infection with Unknown Absolute Neutrophil Count, CTCAE


name: Low Grade Cervical Squamous Intraepithelial Neoplasia

description: A precancerous neoplastic process that affects the cervical squamous epithelium without evidence of invasion. It is usually associated with human papillomavirus infection. It is characterized by the presence of mild atypia in the superficial epithelial layer that may be associated with koilocytosis. Maturation is present in the upper two thirds of the epithelium. Mitotic figures are not numerous and are present in the basal third of the epithelium.


Abandoned Lead

description: The cardiac lead has been left in situ but is not in use. (ACC)


name: Grade 2 Colon Infection with Unknown Absolute Neutrophil Count, CTCAE


UGT1A1*28 Allele Negative

description: An indication that UGT1A1*28 expression has not been detected in a sample.


Cyclitis

description: Inflammation of the ciliary body.


name: Type 1 Diabetes Mellitus with Moderate Nonproliferative Diabetic Retinopathy with Macular Edema, Left Eye

description: Evidence of type 1 diabetes mellitus with moderate nonproliferative diabetic retinopathy with macular edema in the left eye.


name: Unknown Primary Tumor pN0 TNM Finding v8

description: Unknown primary tumor in which no regional lymph node metastases are detected. (from AJCC 8th Ed.)


Grade 4 Gastric Hemorrhage, CTCAE

description: Life-threatening consequences; urgent intervention indicated


name: Grade 2 Vulva Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


Grade 1 Lip Infection, CTCAE

description: Localized, local intervention indicated


Cyanotic Breath Holding

description: A clinical condition in which there is a breath-holding spell associated with cyanotic appearance. (ACC/AHA)


name: Other specified degenerative diseases of nervous system

description: Evidence of other specified degenerative diseases of nervous system not specified elsewhere.


name: Esophagus and Esophagogastric Junction Cancer pT1a TNM Finding v7

description: Esophagus and esophagogastric junction cancer with tumor invading lamina propria or muscularis mucosae. (from AJCC 7th Ed.)


name: Abdomen Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils NOS, CTCAE


inhalant abuse with intoxication

description: Evidence of inhalant abuse with intoxication.


name: Follicular Lymphoma Grade I, Lymph Nodes of Axilla and Upper Limb

description: Evidence of follicular lymphoma grade I in the lymph nodes of axilla and upper limb.


name: Grade 2 Portal Vein Intra-Operative Injury, CTCAE


name: Gastrointestinal Stromal Tumor pT1 TNM Finding v7

description: Gastrointestinal stromal tumor with tumor size 2 cm or less in greatest dimension. (from AJCC 7th Ed.)


name: Pre-Existing Essential Hypertension Complicating Pregnancy, First Trimester

description: Evidence of pre-existing essential hypertension complicating pregnancy in the first trimester.


Pseudoangiomatous stromal hyperplasia

description: A benign proliferation of the stromal cells in the breast.  It is classified as simple, when associated with the presence of slit-like spaces without erythrocytes and as fascicular/proliferative, when spindle cell proliferation without atypia is present.  It is often seen in breast tissue specimens as small foci associated with benign epithelial lesions.  Pseudoangiomatous stromal hyperplasia presenting as a well-circumscribed palpable mass is rare.


name: Major Salivary Gland Cancer pT4a TNM Finding v7

description: Major salivary gland cancer with moderately advanced disease.  Tumor invades skin, mandible, ear canal, and/or facial nerve. (from AJCC 7th Ed.)


name: DYSKERATOSIS CONGENITA, AUTOSOMAL RECESSIVE 1

description: Dyskeratosis congenita caused by autosomal recessive mutation(s) in the NOP10 gene, encoding H/ACA ribonucleoprotein complex subunit 3.


Unresectable Malignant Solid Neoplasm

description: A malignant solid neoplasm that is not amenable to surgical resection.


name: Esophagus and Esophagogastric Junction Cancer pNX TNM Finding v7

description: Esophagus and esophagogastric junction cancer in which the regional lymph nodes cannot be assessed.  (from AJCC 7th Ed.)


name: Grade 5 Cornea Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


name: Merkel Cell Carcinoma of Unspecified Part of Face

description: Evidence of Merkel cell carcinoma of unspecified part of face.


name: Jejunum and Ileum Neuroendocrine Tumor pM1b TNM Finding v8

description: Jejunum and ileum neuroendocrine tumor with metastasis in at least one extrahepatic site (e.g., lung, ovary, nonregional lymph node, peritoneum, bone). (from AJCC 8th Ed.)


Crushing Pain

description: A sense of discomfort or distress that is squeezing or excessively compressing.


name: Grade 1 Ophthalmoplegia and Diplopia, CTCAE


name: Pancreatic Neuroendocrine Tumor cM1c TNM Finding v8

description: Pancreatic neuroendocrine tumor with both hepatic and extrahepatic metastases. (from AJCC 8th Ed.)


Bladder Neuroendocrine Tumor

description: A well-differentiated neuroendocrine neoplasm arising from the bladder. It is characterized by the presence of uniform cells with stippled chromatin and inconspicuous nucleoli. Mitotic activity is low and tumor necrosis is absent.


Gastric Cancer TNM Finding v6

description: A finding about one or more characteristics of gastric cancer, following the rules of the TNM AJCC v6 classification system.


Stage I Prostate Cancer AJCC v8

description: Stage I includes: (cT1a-c, cT2a, N0, M0, PSA less than 10, Grade Group 1); (pT2, N0, M0, PSA less than 10, Grade Group 1). cT1a: Prostate cancer in which the tumor is an incidental histologic finding in 5% or less of tissue resected. cT1b: Prostate cancer in which the tumor is an incidental histologic finding in more than 5% of tissue resected. cT1c: Prostate cancer in which the tumor is identified by needle biopsy found in one or both sides, but not palpable. cT2a: Prostate cancer in which the tumor involves one-half of one side or less. pT2: Prostate cancer which is organ confined. N0: Prostate cancer with no positive regional nodes. M0: Prostate cancer without evidence of distant metastasis. Grade Group 1: Gleason Score 6 or less, Gleason Pattern 3 or less+3. (AJCC 8th ed.)


name: spondylopathy in diseases classified elsewhere in lumbosacral region

description: Evidence of spondylopathy in diseases classified elsewhere in the lumbosacral region.


Electronic Cigarette Smoke Exposure

description: Environmental, occupational or consumer-based exposure to airborne gases and particulates produced by direct or nearby use of an electronic cigarette.


Injection Site Reaction, CTCAE

description: A disorder characterized by an intense adverse reaction (usually immunologic) developing at the site of an injection.


T3a TNM Finding

description: A general term that refers to a TNM finding of a primary tumor usually indicating that the cancer is locally invasive. The definition of T3a TNM finding depends on the specific type of cancer that it refers to; for example, for kidney cancer it refers to a primary tumor that grossly extends into the renal vein or its segmental (muscle containing) branches or the tumor invades perirenal and/or renal sinus fat but does not extends beyond Gerota's fascia; for cervical cancer it refers to a primary tumor that involves the lower third of vagina, without extension to pelvic wall; for liver cancer it refers to the presence of multiple tumors measuring more than 5 cm in greatest dimension.


Grade 3 Jejunal Perforation, CTCAE

description: Invasive intervention indicated


name: Grade 2 Colon or Cecum or Appendix Fistula, CTCAE


name: Grade 3 Esophagus Stricture or Stenosis, CTCAE


name: Grade 2 Tracheostomy Site Bleeding, CTCAE

description: Moderate bleeding; medical intervention indicated


name: Unresectable Gastroesophageal Junction Adenocarcinoma

description: Gastroesophageal junction adenocarcinoma that is not amenable to surgical resection.


name: Mucosal Melanoma of the Head and Neck Pathologic Primary Tumor TNM Finding v8

description: A pathologic finding about one or more characteristics of mucosal melanoma of the head and neck, following the rules of the TNM AJCC v8 classification system as they pertain to staging of the primary tumor.


Recurrent Anaplastic Ependymoma

description: The reemergence of anaplastic ependymoma after a period of remission.


name: Grade 1 Neutrophils and Granulocytes, CTCAE


Grade 2 Hypoparathyroidism, CTCAE

description: Moderate symptoms; medical intervention indicated


name: Grade 5 Mucosa Infection with Unknown Absolute Neutrophil Count, CTCAE


name: Hemoglobin Alpha with Heterozygous Triplication

description: A genetic finding indicating that one copy of chromosome 16 has two functional copies of the hemoglobin alpha (HBA) genes and the other copy of chromosome 16 has three functional copies due to chromosomal rearrangement. This genotype is associated with the alpha thalassemia silent carrier trait.


name: Other systemic atrophy primarily affecting central nervous system in neoplastic disease

description: Evidence of other systemic atrophy primarily affecting central nervous system in neoplastic disease not specified elsewhere.


Grade 3 Pancreatitis, CTCAE

description: Severe pain; vomiting; medical intervention indicated (e.g., analgesia, nutritional support)


name: Uterine Corpus Adenosarcoma pT1 TNM Finding v8

description: Uterine corpus adenosarcoma with tumor limited to the uterus. (from AJCC 8th Ed.)


name: Monoclonal Polymorphic Post-Transplant Lymphoproliferative Disorder


Grade 4 Bronchial Fistula, CTCAE

description: Life-threatening consequences; urgent intervention indicated


name: Intrahepatic Bile Duct Cancer pT0 TNM Finding v7

description: Intrahepatic bile duct cancer with no evidence of primary tumor. (from AJCC 7th Ed.)


Grade 2 Neonatal Constipation, AE

description: An adverse event in a newborn characterized by reduced number of stools or hard stools; apparent discomfort; minor care changes indicated.


name: Grade 3 Colon Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


name: Grade 1 Cranial Nerve III Neuropathy, CTCAE


Anatomic Imaging Concept

description: Concepts created to assist in identifying anatomic areas on radiographic images.


Grade 3 Tracheal Stenosis, CTCAE

description: Stridor or respiratory distress limiting self care ADL; invasive intervention indicated (e.g., stent, laser)


name: malignant melanoma of left eyelid, including canthus

description: Evidence of a malignant melanoma of the left eyelid including the canthus.


name: Other specified malignant neoplasm of skin of eyelid, including canthus

description: Evidence of other malignant neoplasm skin of unspecified eyelid including the canthus not specified elsewhere.


name: Grade 1 Peripheral Motor Neuropathy, CTCAE

description: Asymptomatic; clinical or diagnostic observations only


Metastatic Carcinoma in the Pancreas

description: A carcinoma that has spread to the pancreas from another anatomic site.


Thymic Tumor pM1a TNM Finding v8

description: Thymic tumor with separate pleural or pericardial nodule(s). (from AJCC 8th Ed.)


Body Mass Index Finding

description: The result of a body mass index measurement.


name: Grade 3 Lower Gastrointestinal Hemorrhage NOS, CTCAE


name: Colon or Rectum Neuroendocrine Tumor pN1 TNM Finding v7

description: Colon or rectum neuroendocrine tumor with regional lymph node metastasis. (from AJCC 7th Ed.)


name: Grade 2 Edema of the Head and Neck, CTCAE


Refractory Low Grade Astrocytoma

description: Low grade astrocytoma that is resistant to treatment.


name: Pharynx Mucositis or Stomatitis by Functional or Symptomatic Classification, CTCAE


Best Overall Response

description: The most clinically favorable response recorded from the start of the study treatment until the end of treatment.


name: Complete Response without Minimal Residual Disease

description: Complete response with no detectable signs of disease.


name: Appendiceal Carcinoma cM1b TNM Finding v8

description: Appendiceal carcinoma with intraperitoneal metastasis only, including peritoneal mucinous deposits containing tumor cells. (from AJCC 8th Ed.)


Grade 1 Pelvic Pain, CTCAE

description: Mild pain


Retinoblastoma pT1 TNM Finding v8

description: Intraocular tumor(s) without any local invasion, focal choroidal invasion, or pre-or intralaminar involvement of the optic nerve head. (from AJCC 8th Ed.)


name: Distal Bile Duct Cancer pT4 TNM Finding v8

description: Distal bile duct cancer with tumor involving the celiac axis, superior mesenteric artery, and/or common hepatic artery. (from AJCC 8th Ed.)


name: Grade 4 Bladder Intra-Operative Injury, CTCAE


name: Grade 1 Vas Deferens Anastomotic Leak, CTCAE

description: Asymptomatic diagnostic finding; intervention not indicated


name: Salivary Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


name: Stage IV Renal Pelvis and Ureter Cancer AJCC v8

description: Stage IV includes: (T4, N0, M0); (Any T, N1, M0); (Any T, N2, M0); (Any T, Any N, M1). T4: Tumor invades adjacent organs, or through the kidney into the perinephric fat. N0: No regional lymph node metastasis. N1: Metastasis in a single lymph node, 2 cm or less in greatest dimension. N2: Metastasis in a single lymph node, more than 2 cm in greatest dimension; or multiple lymph nodes. M0: No distant metastasis. M1: Distant metastasis. (AJCC 8th ed.)


name: Pre-Existing Hypertensive Heart Disease Complicating Pregnancy, Unspecified Trimester

description: Evidence of pre-existing hypertensive heart disease complicating pregnancy in an unspecified trimester.


TNFRSF8 Low

description: Indicates that low expression of TNFRSF8 has been detected in a sample.


Ampulla of Vater Neuroendocrine Tumor

description: A well differentiated, low, intermediate, or high grade neoplasm with neuroendocrine differentiation that arises from the ampulla of Vater and periampullary region.


name: Liver Cancer Pathologic Distant Metastasis TNM Finding v6

description: A pathologic finding about one or more characteristics of liver cancer, following the rules of the TNM AJCC v6 classification system as they pertain to distant metastases. TNM pathologic distant metastasis findings are based on clinical findings supplemented by histopathologic examination of one or more tissue specimens acquired during surgery.


name: Posterior Fossa Ependymoma, Not Otherwise Specified

description: A circumscribed ependymoma that arises in the posterior fossa in which molecular analysis for DNA methylation profiling was unsuccessful or not reported.


name: Locally Advanced Prostate Adenocarcinoma

description: A prostatic adenocarcinoma that has spread from its original site of growth to nearby tissues or lymph nodes.


Metastases to abdominal cavity

description: The spread of a malignant neoplasm from a primary site to an unspecified organ in the abdominal cavity.


Negative Pregnancy Test

description: A finding which indicates an individual is not pregnant.


Vulval Infection, CTCAE

description: A disorder characterized by an infectious process involving the vulva.


name: Grade 1 Pharyngeal Anastomotic Leak, CTCAE


Urethral Cancer TNM Finding v7

description: A finding about one or more characteristics of urethral cancer, following the rules of the TNM AJCC v7 classification system.


Grade 3 Vasovagal Reaction, CTCAE

description: Present


Minor Injury/ Illness/Impairment

description: A mild injury, illness or impairment which can be treated with minimal or no intervention.


Conjunctival Oncocytoma

description: A benign epithelial neoplasm that arises from the conjunctiva. It is characterized by the presence of oncocytic cells with abundant eosinophilic and granular cytoplasm.


name: Grade 2 Brain and Spinal Cord Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


name: Atherosclerosis of Autologous Vein Bypass Graft(s) of Right Leg with Ulceration of Other Part of Foot

description: Evidence of atherosclerosis of autologous vein bypass graft(s) of right leg with ulceration of other part of foot.


name: Cervical Cancer Pathologic Regional Lymph Nodes TNM Finding v9

description: A pathologic finding about one or more characteristics of cervical cancer, following the rules of the TNM AJCC v9 classification system as they pertain to staging of regional lymph nodes.


name: Grade 2 Blood Corticotrophin Decreased, CTCAE

description: Symptomatic; medical intervention indicated


name: Grade 4 Sacral Plexus Intra-Operative Injury, CTCAE


Maternal Hemorrhage

description: Uncontrolled bleeding from a pregnant or a woman who has recently given birth.


Rash Maculo-Papular, CTCAE

description: A disorder characterized by the presence of macules (flat) and papules (elevated). Also known as morbillform rash, it is one of the most common cutaneous adverse events, frequently affecting the upper trunk, spreading centripetally and associated with pruritis.


name: Oropharyngeal (p16-Negative) and Hypopharyngeal Cancer TNM Finding v8

description: A finding about one or more characteristics of p16-negative oropharyngeal and hypopharyngeal cancer, following the rules of the TNM AJCC v8 classification system. This staging system applies to p16-negative squamous cell carcinomas of the oropharynx, oropharyngeal cancers without p16 immunostaining performed, and all cancers of the hypopharynx. Minor salivary gland cancers and neuroendocrine carcinomas of the oropharynx and hypopharynx are included in this classification. Oropharyngeal cancers which are p16-positive are staged according to the classification for p16-positive oropharyngeal cancers. (from AJCC 8th Ed.)


Grade 2 Oral Pain, CTCAE

description: Moderate pain; limiting instrumental ADL


Grade 5 Salivary Gland Infection, CTCAE

description: Death


name: Bladder Cancer pT4b TNM Finding v6 and v7

description: Bladder cancer with tumor invading pelvic wall, abdominal wall. (from AJCC 6th and 7th Eds.)


Advanced Malignant Skin Neoplasm

description: A malignant neoplasm of the skin that has spread extensively to other anatomic sites or is no longer responding to treatment.


name: Other Specified Malignant Neoplasm of Anal Skin

description: Evidence of other specified malignant neoplasm of anal skin not specified elsewhere.


Pancreatic Alpha Cell Adenoma

description: A benign endocrine neoplasm arising from the alpha cells of the pancreas.  It produces glucagon.


name: Grade 5 Anal or Perianal Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


name: Lugano Classification Advanced Stage Hodgkin Lymphoma AJCC v8

description: Advanced stage Hodgkin lymphoma based on the Lugano classification criteria. It includes stages III and IV. (from AJCC 8th Ed.)


name: Stage IIA Ampulla of Vater Cancer AJCC v8

description: Stage IIA includes: T3a, N0, M0. T3a: Tumor directly invading the pancreas (up to 0.5 cm). N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 8th ed.)


Grade 4 Uterine Perforation, CTCAE

description: Life-threatening consequences; urgent intervention indicated


name: Type 1 diabetes mellitus with diabetic mononeuropathy

description: Evidence of type 1 diabetes mellitus with diabetic mononeuropathy.


name: Grade 3 Depressed Level of Consciousness, CTCAE

description: Difficult to arouse


name: Direct Infection of Unspecified Joint in Infectious and Parasitic Diseases Classified Elsewhere

description: Evidence of direct infection of unspecified joint in infectious and parasitic diseases classified elsewhere.


Stage IVB Vulvar Cancer AJCC v8

description: Stage IVB includes: Any T, Any N, M1. M1: Distant metastasis (including pelvic lymph node metastasis). (from AJCC 8th Ed.)


name: Grade 4 Central Nervous System Necrosis, CTCAE


name: Type 1 Diabetes Mellitus with Proliferative Diabetic Retinopathy without Macular Edema

description: Evidence of type 1 diabetes mellitus with proliferative diabetic retinopathy without macular edema.


name: Stage III Lentigo Maligna Melanoma AJCC v7

description: Stage III includes: Any T, N1-3, M0.  Stage III is divided into three pathologic subgroups: IIIA, IIIB, and IIIC.  There are no clinical subgroups for stage III.  N1: Cutaneous melanoma with metastasis in one regional lymph node.  N2: Cutaneous melanoma with metastases in 2-3 regional lymph nodes or in transit met(s)/satellite(s) without metastatic nodes.  N3: Cutaneous melanoma with 4 or more metastatic nodes, or matted nodes, or in transit met(s)/satellite(s) with metastatic node(s).  M0: No detectable evidence of distant metastases. (from AJCC 7th Ed.)


Reproductive Endocrine Neoplasm

description: A benign or malignant endocrine neoplasm that arises from the testis or the ovary.


name: Pancreatic Neuroendocrine Tumor pM1 TNM Finding v8

description: Pancreatic neuroendocrine tumor with distant metastasis. (from AJCC 8th Ed.)


name: Grade 5 Eye Infection NOS with Unknown Absolute Neutrophil Count, CTCAE


Anemia due to Decreased Production

description: Anemia that results from a decreased rate of erythropoiesis.


name: Malignant Neoplasm of Long Bones of Right Lower Limb

description: Evidence of a malignant neoplasm of the long bones of right lower limb.


name: Melanoma Metastatic in the Central Nervous System

description: A melanoma that has spread to the central nervous system from its original site of growth, through the hematogenous route.


name: Grade 3 Lymphocyte Count Decreased, CTCAE

description: <500-200/mm3; <0.5-0.2 x 10e9/L


ALK Gene Alteration Negative

description: An indication that mutation, overexpression, fusion or rearrangement involving the ALK gene has not been detected in a sample.


Domestic injury

description: Trauma occurring within the confines of the home environment.


name: Grade 3 Foreign Body Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


Cervical Cancer TNM Finding v8

description: A finding about one or more characteristics of cervical cancer, following the rules of the TNM AJCC v8 classification system.


Antimicrobial Not Susceptible Result

description: The growth of the microorganism is intermediate or resistant to an antimicrobial. This category is used when describing isolates that are above the susceptible interpretive category breakpoint as defined by a standards organization, and, when the "intermediate" breakpoint and the "resistant" breakpoint are defined but not applied; or when "intermediate" and "resistant" interpretive categories are merged/combined.


name: Soft Tissue Sarcoma of the Head and Neck pM1 TNM Finding v8

description: Soft tissue sarcoma of the head and neck with distant metastasis. (from AJCC 8th Ed.)


name: Other Specified Malignant Neoplasm of Skin, Unspecified

description: Evidence of other specified malignant neoplasm of skin not specified elsewhere.


name: Grade 2 Nasal Cavity and Paranasal Sinus Reactions, CTCAE


name: Occlusion and Stenosis of Bilateral Vertebral Arteries

description: Evidence of occlusion and stenosis of bilateral vertebral arteries.


GGT Increased, CTCAE

description: A finding based on laboratory test results that indicate higher than normal levels of the enzyme gamma-glutamyltransferase in the blood specimen. GGT (gamma-glutamyltransferase ) catalyzes the transfer of a gamma glutamyl group from a gamma glutamyl peptide to another peptide, amino acids or water.


ANPEP Negative

description: An indication that ANPEP expression has not been detected in a sample.


BRCA Driver Mutation Negative

description: A genetic finding indicating that disease-causing (driver or deleterious) mutations in BRCA family genes were not detected in a sample.


name: Modified Overall Immune Related Response Criterion, Partial Response

description: The evaluation of the antitumor response shows that the sum of the longest diameters of target and new measurable lesions has decreased by at least 30%.


name: Other Atherosclerosis of Unspecified Type of Bypass Graft(s) of the Extremities, Unspecified Extremity

description: Evidence of other atherosclerosis of unspecified type of bypass graft(s) of the extremities, unspecified extremity not specified elsewhere.


Grade 3 Intracranial Hemorrhage, CTCAE

description: Ventriculostomy, ICP monitoring, intraventricular thrombolysis, or invasive intervention indicated; hospitalization


name: Diabetes Mellitus due to Underlying Condition with Ketoacidosis with Coma

description: Evidence of diabetes mellitus due to underlying condition with ketoacidosis with coma.


name: Gastrointestinal Stromal Tumor Pathologic Primary Tumor TNM Finding v7

description: A pathologic finding about one or more characteristics of gastrointestinal stromal tumor, following the rules of the TNM AJCC v7 classification system as they pertain to staging of the primary tumor.


name: Penis Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


name: Extragonadal primary germ cell tumor mixed stage I


name: Rheumatoid Heart Disease with Rheumatoid Arthritis of Left Shoulder

description: Evidence of rheumatoid heart disease with rheumatoid arthritis of left shoulder.


Eyelid Carcinoma pT2c TNM Finding v8

description: Eyelid carcinoma with tumor measuring more than 10 mm but 20 mm or less in greatest dimension involving the full thickness of the eyelid. (from AJCC 8th Ed.)


name: Rheumatoid Bursitis, Unspecified Ankle and Foot

description: Evidence of rheumatoid bursitis in an unspecified ankle and foot.


name: Grade 2 Skin Intra-Operative Injury, CTCAE


name: Neck Infection with Unknown Absolute Neutrophil Count NOS, CTCAE


name: Grade 5 Urethra Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


name: Other Juvenile Arthritis, Unspecified Knee

description: Evidence of other juvenile arthritis in an unspecified knee not specified elsewhere.


name: Cerebral Infarction due to Unspecified Occlusion or Stenosis of Bilateral Carotid Artery

description: Evidence of cerebral infarction due to an unspecified occlusion or stenosis of the bilateral carotid artery.


Grade 5 Aortic Injury, CTCAE

description: Death


Laryngeal Cancer cN2 TNM Finding v8

description: Laryngeal cancer with metastasis in a single ipsilateral lymph node, more than 3 cm but not more than 6 cm in greatest dimension and ENE(-); or metastases in multiple ipsilateral lymph nodes, none more than 6 cm in greatest dimension and ENE(-); or metastasis in bilateral or contralateral lymph nodes, none more than 6 cm in greatest dimension and ENE(-). (from AJCC 8th Ed.)


M1a TNM Finding

description: A TNM finding indicating the spread of cancer to distant anatomic sites.  The definition of M1a TNM finding depends on the specific type of cancer that it refers to; for example, for colorectal cancer it refers to metastasis confined to one organ or site (e.g., liver, lung, ovary, nonregional node); for prostate cancer it refers to metastasis to non-regional lymph node(s); for bone cancer it refers to metastasis to the lung.


name: Enteropathic Arthropathies, Unspecified Ankle and Foot

description: Evidence of enteropathic arthropathies in an unspecified ankle and foot.


Total Thyroxine Level Finding

description: A finding that indicates the amount of total thyroxine in a sample.


name: Non-Rheumatic Tricuspid Valve Insufficiency

description: Evidence of non-rheumatic tricuspid valve insufficiency.


Increased Concomitant Drug AUC

description: Increased area under the plot of plasma concentration of a concomitant drug against time after its administration.


Hemoglobin Alpha cis-Deletion Genotype

description: A genetic finding indicating that one copy of chromosome 16 has two functional copies of the hemoglobin alpha (HBA) genes and the other copy of has no functional HBA genes. This genotype is associated with the alpha thalassemia trait.


name: Grade 4 Laryngopharyngeal Dysesthesia, CTCAE

description: Life-threatening consequences


Spread of Lymphoma

description: A finding indicating the spread of a lymphoma from a nodal or extranodal primary site.


name: Grade 1 Esophagus Intra-Operative Injury, CTCAE


name: Grade 5 Neonatal Culture Positive Sepsis, AE

description: A culture positive sepsis adverse event in a newborn which results in death.


Grade 5 Pharyngeal Stenosis, CTCAE

description: Death


Childhood Aneurysmal Bone Cyst

description: An aneurysmal bone cyst that occurs during childhood.


name: Grade 4 Mediastinum Infection NOS with Unknown Absolute Neutrophil Count, CTCAE


name: Appendiceal Carcinoid pT1b TNM Finding v7

description: Appendiceal carcinoid with tumor more than 1 cm but not more than 2 cm in greatest dimension. (from AJCC 7th Ed.)


name: Grade 3 Neonatal Coagulation Disorder, AE

description: An adverse event in a newborn characterized by biochemical or clinical coagulation abnormalities; requiring intervention.


Grade 5 Injury To Carotid Artery, CTCAE

description: Death


Grade 3 Lip Pain, CTCAE

description: Severe pain; limiting self care ADL


Neonatal Sinus Tachycardia, AE

description: An adverse event in a newborn characterized by an abnormally high heart rate for age.


Stage IB Vulvar Cancer AJCC v8

description: Stage IB includes: T1b, N0, M0. T1b: Lesion measuring more than 2 cm, or any size with stromal invasion of more than 1.0 mm, confined to the vulva and/or perineum. N0: No regional lymph node metastasis.  M0: No distant metastasis. (AJCC 8th Ed.)


Marijuana Smoke Exposure

description: Environmental, occupational or consumer-based exposure to airborne gases and particulates produced by direct or nearby use of a vaporized or combusted product made from the leaves and flowers of the cannabis plant.


name: Grade 1 Other Sexual Reproductive Function, CTCAE


Grade 2 Prostatic Obstruction, CTCAE

description: Symptomatic; elective intervention indicated


name: Sezary's disease of lymph nodes of axilla and upper limb

description: Evidence of Sezary disease in the lymph nodes of axilla and upper limb.


name: B-Cell Prolymphocytic Leukemia not Having Achieved Remission

description: Evidence of B-cell prolymphocytic leukemia not having achieved remission.


Iris Melanoma pT4 TNM Finding v8

description: Iris melanoma with extrascleral extension. (from AJCC 8th Ed.)


name: Soft Tissue Sarcoma of the Abdomen and Thoracic Visceral Organs pT2b TNM Finding v8

description: Soft tissue sarcoma of the abdomen and thoracic visceral organs with tumor extending beyond serosa (mesentery). (from AJCC 8th Ed.)


Breast Cancer pM0 TNM Finding

description: Breast cancer in which there is no evidence of distant metastasis. (from AJCC 6th Ed.)


name: Grade 3 Colon or Cecum or Appendix Necrosis, CTCAE


pN1c TNM Finding

description: A pathologic regional lymph node TNM finding. The definition of pN1c finding depends on the particular type of cancer that it refers to; for example, for breast cancer, pN1c finding is defined as follows: cancer with metastasis in 1 to 3 axillary lymph nodes and in internal mammary nodes with microscopic disease detected by sentinel lymph node dissection but not clinically apparent. (from AJCC 6th Ed.)


Stage IIA Pancreatic Cancer AJCC v8

description: Stage IIA includes: T3, N0, M0. T3: Tumor measuring more than 4 cm in greatest dimension. N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 8th ed.)


Malignant melanoma of lip

description: Evidence of a malignant melanoma of the lip.


name: Grade 3 Rectum Mucositis or Stomatitis by Functional or Symptomatic Classification, CTCAE


name: Drug or Chemical Induced Diabetes Mellitus with Moderate Non-Proliferative Diabetic Retinopathy with Macular Edema, Right Eye

description: Evidence of drug or chemical induced diabetes mellitus with moderate non-proliferative diabetic retinopathy with macular edema in the right eye.


name: Grade 1 Lower Extremity Artery Intra-Operative Injury, CTCAE


Reiter's Disease, Right Hip

description: Evidence of Reiter's disease in the right hip.


Cervical Cancer cT1b TNM Finding v8

description: Cervical cancer with clinically visible lesion confined to the cervix. (from AJCC 8th Ed.)


name: Grade 1 Extraocular Muscle Paresis, CTCAE

description: Asymptomatic; clinical or diagnostic observations only


name: Clonal Hematopoiesis of Indeterminate Potential

description: A term that refers to the presence of somatic mutations in bone marrow or peripheral blood cells in individuals who may be cytopenic but do not have morphologic evidence of hematologic neoplasia. Its prevalence rises with age and is found in approximately 10% of individuals aged 70 to 80. It is associated with an increased risk of hematologic neoplasia. Mutations in the DNMT3A, TET2, or ASXL1 genes are usually identified. Approximately 10%-40% of individuals with age-related clonal hematopoiesis will progress to meet the diagnostic criteria for clonal hematopoiesis of indeterminate potential.


name: Grade 4 Larynx Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


name: Grade 4 Vagina Intra-Operative Injury, CTCAE


Blood Cardiac Troponin Increased

description: A laboratory test result which indicates increased levels of cardiac troponin in a biological specimen.


Pleural fistula

description: An abnormal communication between the pleural cavity and another anatomic site.


name: Drug or Chemical Induced Diabetes Mellitus with Unspecified Complications

description: Evidence of drug or chemical induced diabetes mellitus with unspecified complications.


Grade 3 Lung Infection, CTCAE

description: IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated


name: Grade 5 Trachea Mucositis or Stomatitis by Functional or Symptomatic Classification, CTCAE


Spermatic Cord Hemorrhage, CTCAE

description: A disorder characterized by bleeding from the spermatic cord.


name: Atherosclerosis of Unspecified Type of Bypass Graft(s) of the Left Leg with Ulceration of Thigh

description: Evidence of atherosclerosis of unspecified type of bypass graft(s) of the left leg with ulceration of thigh.


name: Chronic Lobular Hepatitis NEC in NCI Thesaurus

description: Evidence of chronic lobular hepatitis, not elsewhere classified.


name: Appendiceal Carcinoma Pathologic Distant Metastasis TNM Finding v7

description: A pathologic finding about one or more characteristics of appendiceal carcinoma, following the rules of the TNM AJCC v7 classification system as they pertain to distant metastases.  There is no pathologic M0 for appendiceal carcinoma. (from AJCC 7th Ed.)


Refractory Fibrosarcoma

description: Fibrosarcoma that is resistant to treatment.


name: Granulomatosis with polyangiitis with renal involvement

description: Evidence of Wegener's granulomatosis with renal involvement.


name: Right Anterior Basal Transition Zone of Prostate

description: The region of the prostate that is located on the anatomical right side of the anterior portion of the basal division of the transition zone.


Metastatic Melanoma in the Skin

description: A melanoma that has spread to the skin from a cutaneous or extracutaneous primary site.


Substance-Induced Anxiety Disorder

description: An anxiety disorder in which the symptoms of anxiety have been determined to be etiologically related to the direct physiological effects of a substance (i.e., a drug of abuse, a medication, or toxin exposure).


Grade 1 Hypoglycemia, CTCAE

description: <LLN-55 mg/dL; <LLN-3.0 mmol/L


name: Drug-Induced Movement Disorder, Unspecified

description: Evidence of drug-induced movement disorder.


name: Hodgkin's disease lymphocyte predominance type recurrent

description: An antiquated term that refers to the reemergence of either nodular lymphocyte predominant Hodgkin lymphoma or lymphocyte-rich classical Hodgkin lymphoma after a period of remission.


name: Surrounds Basilar Artery Greater than 180 Degrees

description: A radiographic finding that the tumor extent surrounds the basilar artery greater than 180 degrees.


name: Other Stimulant Dependence with Stimulant-Induced Sleep Disorder

description: Evidence of other stimulant dependence with stimulant-induced sleep disorder not specified elsewhere.


name: Clinical Stage I Esophageal Adenocarcinoma AJCC v8

description: Stage I includes: T1, N0, M0. T1: Tumor invades the lamina propria, muscularis mucosae, or submucosa. N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 8th ed.)


name: Grade 2 Larynx Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


name: Bladder Cancer Pathologic Regional Lymph Nodes TNM Finding v7

description: A pathologic finding about one or more characteristics of bladder cancer, following the rules of the TNM AJCC v7 classification system as they pertain to staging of regional lymph nodes.  Note: regional lymph nodes include both primary and secondary drainage regions.  All other nodes above the aortic bifurcation are considered distant lymph nodes. (from AJCC 7th Ed.)


name: Prostate Cancer Clinical Primary Tumor TNM Finding v7

description: A clinical finding about one or more characteristics of prostate cancer, following the rules of the TNM AJCC v7 classification system as they pertain to staging of the primary tumor.  (from AJCC 7th Ed.)


name: Exocrine Pancreatic Cancer pN0 TNM Finding v6

description: Exocrine pancreatic cancer with no evidence of regional lymph node metastasis. (from AJCC 6th Ed.)


Frank Umbilical Cord Prolapse

description: A situation in which the umbilical cord is prolapsed through the cervix and into the vagina.


Grade 2 Rectal Fistula, CTCAE

description: Symptomatic, invasive intervention not indicated


Grade 2 Sneezing, CTCAE

description: Moderate symptoms; medical intervention indicated


name: Leiomyosarcoma and Endometrial Stromal Sarcoma pTX TNM Finding v7

description: Primary tumor cannot be assessed. (from AJCC 7th Ed.)


name: Stage IIIC Fallopian Tube Cancer AJCC v8

description: Stage IIIC includes: T3c, N0/N1, M0. T3c: Fallopian tube cancer with macroscopic peritoneal metastasis beyond the pelvis more than 2 cm in greatest dimension with or without metastasis to the retroperitoneal lymph nodes (includes extension of tumor to capsule of liver and spleen without parenchymal involvement of either organ). N0: No regional lymph node metastasis. N1: Positive retroperitoneal lymph nodes only (histologically confirmed). M0: No distant metastasis. (AJCC 8th Ed.)


T1a1 Stage Finding

description: A general term that refers to a TNM finding of a primary tumor limited to the site of growth. The definition of T1a1 TNM finding depends on the specific type of cancer to which it refers: for example, for cervical carcinoma it indicates measured stromal invasion equal or less than 3 mm in depth.


name: Overlapping malignant neoplasm of heart, mediastinum and pleura

description: Evidence of a malignant neoplasm of overlapping sites of the heart, mediastinum and pleura.


name: Grade 3 Recurrent Laryngeal Nerve Intra-Operative Injury, CTCAE


Vascular hemorrhagic disorders

description: A hemorrhagic disorder that is caused by pathologic changes in the vasculature.


Grade 1 Seizure, CTCAE

description: Brief partial seizure and no loss of consciousness


name: Grade 4 Nasal Cavity Intra-Operative Injury, CTCAE


name: Type 2 Diabetes Mellitus with Proliferative Diabetic Retinopathy with Traction Retinal Detachment not Involving the Macula, Bilateral

description: Evidence of type 2 diabetes mellitus with proliferative diabetic retinopathy with traction retinal detachment not involving the macula that is bilateral.


Grade 5 Myocarditis, CTCAE

description: Death


name: Hemiplegia following Other Non-Traumatic Intracranial Hemorrhage Affecting Left Dominant Side

description: Evidence of hemiplegia following other non-traumatic intracranial hemorrhage affecting left dominant side.


name: Lip and Oral Cavity Cancer cN2 TNM Finding v8

description: Lip and oral cavity cancer with metastasis in a single ipsilateral lymph node larger than 3 cm but not larger than 6 cm in greatest dimension and ENE(-); or metastases in multiple ipsilateral lymph nodes, none larger than 6 cm in greatest dimension and ENE(-); or metastases in bilateral or contralateral lymph nodes, none larger than 6 cm in greatest dimension, and ENE(-). (from AJCC 8th Ed.)


Pregnancy Mood Swing

description: The fluctuations in the mental and emotional state of an individual during pregnancy.


Adverse Event Associated with Death

description: An adverse event resulting in death.


Peripheral Vascular Insufficiency

description: A condition in which there is inadequate blood flow through the peripheral blood vessels due to intrinsic disease of the vasculature.


name: Rash and Dermatitis Associated with Radiation Excluding Chemoradiation, CTCAE


name: Primary Cutaneous B-Cell/T-Cell (Non-MF/SS) Lymphoma T2c TNM Finding v8

description: All disease encompassing in a 30-cm or more circular area. (from AJCC 8th Ed.)


name: Grade 4 Upper Airway NOS Intra-Operative Injury, CTCAE


name: Child Intoxication With Breast Implant Material Ingredients

description: Children affected by toxins may be due to silicone breast implants and their effects on unborn children and from breastfeeding.


Grade 2 Edema Trunk, CTCAE

description: Readily apparent obscuration of anatomic architecture; obliteration of skin folds; readily apparent deviation from normal anatomic contour; limiting instrumental ADL


name: Fallopian Tube Cancer pT3b TNM Finding v7

description: Fallopian tube cancer with macroscopic peritoneal metastasis outside the pelvis 2 cm or less in greatest dimension. (from AJCC 7th Ed.)


name: Cutaneous Melanoma pM1c(0) TNM Finding v8

description: Cutaneous melanoma with distant metastasis to non-CNS visceral sites with or without M1a or M1b sites of disease.  LDH level not elevated. (from AJCC 8th Ed.)


Kidney Cancer pT3b TNM Finding v6

description: Kidney cancer with tumor grossly extending into the renal vein or its segmental (muscle-containing) branches, or vena cava below the diaphragm. (from AJCC 6th Ed.)


name: Grade 5 Arachnoiditis and Meningismus and Radiculitis, CTCAE


Petroleum Hydrocarbon Compound Exposure

description: Environmental, occupational, or consumer-based exposure to the volatile organic compounds and polycyclic aromatic hydrocarbons that are present in and produced during refinement of petroleum products.


name: Uterine Corpus Adenosarcoma pT4 TNM Finding v8

description: Uterine corpus adenosarcoma with tumor invading bladder or rectum. (from AJCC 8th Ed.)


Grade 5 Mucositis Oral, CTCAE

description: Death


name: Grade 1 Large Bowel Mucositis or Stomatitis by Clinical Examination Classification, CTCAE


name: Amnestic disorders due to a general medical condition

description: A disorder involving memory impairment (either anterograde or retrograde) that is etiologically linked to the direct physiological consequence of a general medical condition. The memory impairment is not the result of a delirium or dementia.


name: DNA Methylation-Dependent Predicted Disease Class

description: A genetic finding that predicts the disease type based on the DNA methylation profile of the sample.


name: Advanced Gastric Small Cell Neuroendocrine Carcinoma

description: A gastric small cell neuroendocrine carcinoma that has spread extensively to other anatomic sites or is no longer responding to treatment.


name: Grade 4 Endocrine Disorders - Other, Specify, CTCAE

description: Life-threatening consequences; urgent intervention indicated


Hypointensity

description: Areas of low intensity on types of imaging scans; they appear darker in color and are often seen with various disease processes.


name: Leakage of biological heart valve graft, subsequent encounter

description: Evidence of leakage of biological heart valve graft, subsequent encounter.


name: Grade 3 Intraoperative Cardiac Injury, CTCAE

description: Primary repair of injured organ/structure indicated


name: Hemoglobin Beta Homozygous Null Genotype

description: A genetic finding indicating that both copies of chromosome 16 each have a copy of the hemoglobin beta gene (HBB) with loss of function or gene deletion mutations (B0). This genotype is associated with beta thalassemia major.


Eczema, CTCAE

description: A disorder characterized by skin which becomes itchy, red, inflamed, crusty, thick, scaly, and/or forms blisters.


Eyelid Carcinoma cN2a TNM Finding v8

description: Eyelid carcinoma with metastasis in a single ipsilateral regional lymph node, measuring more than 3 cm in greatest dimension, or in bilateral or contralateral lymph nodes documented based on clinical evaluation or imaging findings. (from AJCC 8th Ed.)


Subdural Hemorrhage Related to Birth

description: Bleeding within the subdural space occurring during labor and/or delivery.


name: Metastatic Extrapulmonary Small Cell Neuroendocrine Carcinoma

description: Extrapulmonary small cell neuroendocrine carcinoma that has spread to another anatomic site.


name: Exocrine Pancreatic Cancer pM0 TNM Finding

description: Exocrine pancreatic cancer with no evidence of distant metastasis. (from AJCC 6th Ed.)


name: Cerebral Infarction due to Thrombosis of Right Cerebellar Artery

description: Evidence of cerebral infarction due to a thrombosis of the right cerebellar artery.


Serious Injury/Illness/Impairment

description: A severe injury, illness or impairment which requires hospitalization or medical intervention.


Skin Lesion More Than 200 mm

description: A skin lesion that measures more than 200 mm in greatest dimension.


Hepatic coma due to viral hepatitis

description: Evidence of unspecified viral hepatitis with hepatic coma.


name: Melanoma of the Conjunctiva pN1 TNM Finding v7

description: Melanoma of the conjunctiva with regional lymph node metastasis. (from AJCC 7th Ed.)


name: Grade 4 Lung Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


name: Pancreatic Mucinous-Cystic Neoplasm, Low Grade

description: A non-invasive mucinous cystic neoplasm that arises from the pancreas and is characterized by the presence of mild dysplasia and absence of mitotic figures.


Breast Cancer pN2 TNM Finding v6

description: Breast cancer with metastasis in 4 to 9 axillary lymph nodes or in clinically apparent internal mammary lymph nodes in the absence of axillary lymph node metastasis. (from AJCC 6th Ed.)


name: Encounter for Adequacy Testing for Peritoneal Dialysis

description: Evidence of encounter for adequacy testing for peritoneal dialysis.


Grade 4 Prostatic Hemorrhage, CTCAE

description: Life-threatening consequences; urgent intervention indicated


name: Hereditary coagulation factor deficiency

description: An inherited blood coagulation disorder characterized by deficiency of one of the coagulation factors, resulting in bleeding.


name: Grade 1 Congenital, Familial and Genetic Disorders - Other, Specify, CTCAE

description: Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated


Cytomegalovirus End-Organ Disease

description: Tissue-invasive cytomegalovirus infection, typically seen in solid-organ transplant recipients.


name: Grade 5 Artery Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


Breast Cancer pT4c TNM Finding v8

description: Breast cancer in which both T4a and T4b are present. (from AJCC 8th Ed.)


Grade 4 Fibrinogen Decreased, CTCAE

description: <0.25 x LLN; if abnormal, 75% decrease from baseline; absolute value <50 mg/dL


name: Grade 3 Hemorrhage and Bleeding, CTCAE Associated with Surgery, CTCAE


Lung Cancer cM0 TNM Finding v8

description: Lung cancer without distant metastasis. (from AJCC 8th Ed.)


name: Head and Neck Cancer cN2c TNM Finding v8

description: Head and neck cancer with metastasis in bilateral or contralateral lymph nodes, none larger than 6 cm in greatest dimension and ENE(-). (from AJCC 8th Ed.)


Myelofibrosis due to another disorder

description: Myelofibrosis that develops in patients with a history of hematologic malignancies or toxic injury to the bone marrow.


Grade 4 Spasticity, CTCAE

description: Life-threatening consequences; unable to move active or passive range of motion


name: Follicular Lymphoma Grade IIIb, Extranodal and Solid Organ Sites

description: Evidence of follicular lymphoma grade IIIb in the extranodal and solid organ sites.


Neuropathic Pain

description: Chronic pain caused by damage to nerve fibers.  It is usually associated with tissue injury.


Astler-Coller A Colon Carcinoma

description: Stage I includes: (T1, N0, M0) and (T2, N0, M0).  T1: Tumor invades submucosa.  T2: Tumor invades muscularis propria.  N0: No regional lymph node metastasis.  M0: No distant metastasis. (AJCC 6th ed.)


opioid dependence uncomplicated

description: Evidence of opioid dependence, uncomplicated.


name: Carcinoma in situ of respiratory system, unspecified

description: Evidence of carcinoma in situ of the respiratory system.


Hyperglycemia Artifact

description: An imaging artifact resulting from hyperglycemia of the patient.


name: Prostate Ductal Adenocarcinoma, Papillary Pattern

description: A prostate ductal adenocarcinoma characterized by the presence of a papillary growth pattern.


Grade 1 Aortic Valve Disease, CTCAE

description: Asymptomatic valvular thickening with or without mild valvular regurgitation or stenosis by imaging


Grade 2 Dizziness, CTCAE

description: Moderate unsteadiness or sensation of movement; limiting instrumental ADL


name: Intrahepatic Bile Duct Cancer Clinical TNM Finding v8

description: A clinical finding about one or more characteristics of intrahepatic bile duct cancer, following the rules of the TNM AJCC v8 classification system.


name: Pathologic Stage 0 Esophageal Adenocarcinoma AJCC v8

description: Stage 0 includes: Tis, N0, M0, GN/A. Tis: High-grade dysplasia, defined as malignant cells confined to the epithelium by the basement membrane. N0: No regional lymph node metastasis. M0: No distant metastasis. GN/A: Grade non-applicable. (AJCC 8th ed.)


name: diabetes mellitus type 1 with diabetic neuropathic arthropathy

description: Evidence of type 1 diabetes mellitus with diabetic neuropathic arthropathy.


name: Perihilar Bile Duct Cancer pN2 TNM Finding v8

description: Perihilar bile duct cancer with four or more positive lymph nodes involving the hilar, cystic duct, common bile duct, hepatic artery, posterior pancreatoduodenal, and portal vein lymph nodes. (from AJCC 8th Ed.)


name: Colorectal Neuroendocrine Tumor Pathologic Regional Lymph Nodes TNM Finding v8

description: A pathologic finding about one or more characteristics of a colorectal neuroendocrine tumor, following the rules of the TNM AJCC v8 classification system as they pertain to staging of regional lymph nodes.


Grade 5 Hypermagnesemia, CTCAE

description: Death


name: Grade 2 Infusion Site Extravasation, CTCAE

description: Erythema with associated symptoms (e.g., edema, pain, induration, phlebitis)


Early Favorable Hodgkin Lymphoma

description: An early Hodgkin lymphoma with favorable prognosis.


Colorectal Cancer pN2a TNM Finding v7

description: Colorectal cancer with metastasis in 4-6 regional lymph nodes. (from AJCC 7th Ed.)


name: Rheumatoid Arthritis of Right Shoulder with Involvement of Organs and Systems

description: Evidence of rheumatoid arthritis of right shoulder with involvement of organs and systems.


Grade 5 Neonatal Pneumothorax, AE

description: A pneumothorax adverse event in a newborn which results in death.


name: Testicular Cancer Clinical Distant Metastasis TNM Finding v8

description: A clinical finding about one or more characteristics of testicular cancer, following the rules of the TNM AJCC v8 classification system as they pertain to distant metastases.


Grade 2 Salivary Gland Infection, CTCAE

description: Moderate symptoms; oral intervention indicated (e.g., antibiotic, antifungal, or antiviral)


Spinal Fracture, CTCAE

description: A finding of traumatic injury to the spine in which the continuity of a vertebral bone is broken.


Facial Muscle Weakness, CTCAE

description: A disorder characterized by a reduction in the strength of the facial muscles.


Jejunal Stenosis, CTCAE

description: A disorder characterized by a narrowing of the lumen of the jejunum.


name: Grade 5 Duodenum Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


name: Merkel Cell Carcinoma Clinical Distant Metastasis TNM Finding v7

description: A clinical finding about one or more characteristics of Merkel cell carcinoma, following the rules of the TNM AJCC v7 classification system as they pertain to distant metastases. (from AJCC 7th Ed.)


name: Grade 1 Larynx Mucositis or Stomatitis by Functional or Symptomatic Classification, CTCAE


name: Non-Neoplastic Chronic Respiratory System Disorder

description: A non-neoplastic longstanding disorder of the respiratory system.


Stage IV Prostate Cancer AJCC v8

description: Stage IV includes: IVA: Any T, N1, M0, PSA: Any, Grade Group: Any; IVB: Any T, N0, M1, PSA: Any, Grade Group: Any. N0: Prostate cancer with no positive regional nodes. N1: Prostate cancer with metastases in regional node(s). M0: Prostate cancer without evidence of distant metastasis. M1: Prostate cancer with distant metastasis. (AJCC 8th ed.)


name: Esophagus Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


name: Conjunctival Melanoma pTis TNM Finding v8

description: Conjunctival melanoma confined to the conjunctival epithelium. (from AJCC 8th Ed.)


name: Gastrointestinal Stromal Tumor pN0 TNM Finding v7

description: Gastrointestinal stromal tumor with no evidence of metastasis to regional lymph nodes. (from AJCC 7th Ed.)


name: Gestational Trophoblastic Neoplasm pM1a TNM Finding v8

description: Gestational trophoblastic neoplasm with lung metastasis. (from AJCC 8th Ed.)


name: Monoclonal Paraproteinemia Present in Lower than Myeloma Levels

description: An indication that the detected amount of monocolonal paraproteinemia in a sample is lower than the range of levels that are associated with myeloma.


name: Human immunodeficiency virus leukoencephalopathy


Childhood Kidney Disorder

description: A kidney disorder that appears during childhood.


name: Paranasal Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


Grade 2 Hyperglycemia, CTCAE

description: Change in daily management from baseline for a diabetic; oral antiglycemic agent initiated; workup for diabetes


Lungs Complete Response GvHD

description: Either normal %FEV1, alkaline phosphatase, and total bilirubin after previous elevation of 1 or more or an NIH lung symptom score of 0 following GvHD involvement.


Mild hypoxic ischemic encephalopathy

description: Evidence of mild hypoxic ischemic encephalopathy.


Microbial IC95 Fold Change from Ref

description: A fold change based on the concentration of a specific drug expected to produce 95 percent inhibition on the enzymatic activity of a microbial organism; it is a ratio calculated by the IC95 Subject Result divided by the IC95 Reference Control Result.


Grade 5 Anal Hemorrhage, CTCAE

description: Death


name: Grade 1 Thrombotic Microangiopathy, CTCAE


Tobacco Pipe Smoke Exposure

description: Environmental, occupational or consumer-based exposure to airborne gases and particulates produced by direct or nearby use of a tobacco pipe.


name: Grade 4 Mucosa Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


name: Grade 4 Phrenic Nerve Dysfunction, CTCAE


Emotional problems

description: A perceived issue with a person's emotional wellbeing.


name: Other Specified Diabetes Mellitus with Moderate Nonproliferative Diabetic Retinopathy without Macular Edema, Unspecified Eye

description: Evidence of other specified diabetes mellitus with moderate nonproliferative diabetic retinopathy without macular edema, unspecified eye not specified elsewhere.


PCA3 Score Greater than 35

description: An indication that the ratio of prostate cancer antigen 3 (PCA3) RNA to prostate specific antigen (PSA) mRNA multiplied by 1000 is greater than 35.


name: Physical Examination Clinically Significant

description: An indication or description that the outcome of the physical examination was clinically significant.


name: Bladder Cancer Pathologic TNM Finding v8

description: A pathologic finding about one or more characteristics of bladder cancer, following the rules of the TNM AJCC v8 classification system.


Grade 4 Rectal Anastomotic Leak, CTCAE

description: Life-threatening consequences; urgent operative intervention indicated


name: Distal Bile Duct Cancer pT1 TNM Finding v8

description: Distal bile duct cancer with tumor invading the bile duct wall with a depth less than 5 mm. (from AJCC 8th Ed.)


Urethral Cancer Clinical TNM Finding v8

description: A clinical finding about one or more characteristics of urethral cancer, following the rules of the TNM AJCC v8 classification system.


Favorable Response

description: No new lesions(s) and a decrease in tumor size, or a reduction in central necrosis or attenuation in one or more enhancing lesions, based on pre-defined thresholds.


Grade 2 Concentration Impairment, CTCAE

description: Moderate impairment in attention or decreased level of concentration; limiting instrumental ADL


name: Ampulla of Vater Cancer Pathologic Primary Tumor TNM Finding v7

description: A pathologic finding about one or more characteristics of ampulla of Vater cancer, following the rules of the TNM AJCC v7 classification system as they pertain to staging of the primary tumor.


Grade 2 Bile Duct Stenosis, CTCAE

description: Symptomatic; altered GI function; IV fluids indicated <24 hrs


PSA Level Greater than Ten

description: A blood concentration of prostate specific antigen greater than 10 ng/mL.


name: Postneoadjuvant Therapy Stage IVA Gastroesophageal Junction Adenocarcinoma AJCC v8

description: Stage IVA includes: (T4a, N1-2, M0); (T4a, NX, M0); (T4b, N0-2, M0); (Any T, N3, M0). T4a: Tumor invades the pleura, pericardium, azygos vein, diaphragm, or peritoneum. T4b: Tumor invades other adjacent structures, such as the aorta, vertebral body, or airway. NX: Regional lymph nodes cannot be assessed. N0: No regional lymph node metastasis. N1: Tumor with metastasis in one or two regional lymph nodes. N2: Tumor with metastasis in three to six regional lymph nodes. N3: Tumor with metastasis in seven or more regional lymph nodes. M0: No distant metastasis. (AJCC 8th ed.)


Clear cell tumor

description: A purely morphologic term that describes a neoplasm in which all or the majority of the neoplastic cells have a clear cytoplasm, when examined under light microscopy, using the conventional staining method (H-E). This term does not provide any information about the nature of the neoplasm (benign or malignant), cell of origin (e.g. epithelial versus mesenchymal versus hematopoietic), or prognosis. Further examination using special stains and/or immunohistochemistry is required to appropriately classify this tumor.


High-CSD Melanoma

description: A cutaneous melanoma that develops on sun-exposed sites with a high degree of cumulative sun damage (CSD).


Recurrent Malignant Endocrine Neoplasm

description: Reemergence of a malignant endocrine neoplasm after a period of remission.


name: Anemia due to disorders of nucleotide metabolism

description: A group of hemolytic anemias that result from either the deficiency or overproduction of several enzymes involved in metabolizing nucleotides.


Hyperlipidemia, CTCAE

description: A disorder characterized by laboratory test results that indicate an elevation in the concentration of lipids in blood.


name: Scrotum Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


Grade 3 Rectal Fissure, CTCAE

description: Invasive intervention indicated


Macrometastasis

description: Metastasis that is clinically obvious.


Gastrointestinal complication

description: Any disorder of the organs of the digestive system occurring as a consequence of injury to the digestive system.


Metastatic Neuroendocrine Tumor

description: A neuroendocrine tumor that has spread from its original site of growth to another anatomic site.


name: Adrenal Gland Pheochromocytoma and Sympathetic Paraganglioma by AJCC v8 Stage

description: A term that refers to the staging of adrenal gland pheochromocytoma and sympathetic paraganglioma, following the rules of the TNM AJCC v8 classification system. Parasympathetic paragangliomas are not staged because they are largely benign. This staging system does not apply to neuroendocrine tumors of the pancreas (are staged according to the classification for neuroendocrine tumors of the pancreas) and carotid body tumors (not staged). (from AJCC 8th Ed.)


New or Worsening Symptom

description: The subjective evidence of disease perceived by the patient that can be classified as new or worsening


name: Drug or Chemical Induced Diabetes Mellitus with Severe Non-Proliferative Diabetic Retinopathy with Macular Edema, Left Eye

description: Evidence of drug or chemical induced diabetes mellitus with severe non-proliferative diabetic retinopathy with macular edema in the left eye.


name: Abnormal Phenolsulfonphthalein Test Result

description: A laboratory test result indicating other than normal parameters after a phenolsulfonphthaliein test.


SDHA Negative

description: An indication that expression of SDHA has not been detected in a sample.


Recurrent Retinoblastoma

description: The reemergence of retinoblastoma after a period of remission.


Radiation injury of bone marrow

description: Radiation injury of the hematopoietic system.


name: Malignant Melanoma of Other Parts of Face

description: Evidence of a malignant melanoma of other parts of the face.


Anal Cancer cM1 TNM Finding v8

description: Anal cancer with distant metastasis. (from AJCC 8th Ed.)


name: Diabetes Mellitus due to Underlying Condition with Moderate Non-Proliferative Diabetic Retinopathy without Macular Edema

description: Evidence of diabetes mellitus due to underlying condition with moderate non-proliferative diabetic retinopathy without macular edema.


name: Type 2 diabetes mellitus with established diabetic nephropathy

description: Evidence of type 2 diabetes mellitus with diabetic nephropathy.


name: Gallbladder Cancer Pathologic Regional Lymph Nodes TNM Finding v6

description: A pathologic finding about one or more characteristics of gallbladder cancer, following the rules of the TNM AJCC v6 classification system as they pertain to staging of regional lymph nodes.


name: Cutaneous Squamous Cell Carcinoma of the Head and Neck pTis TNM Finding v8

description: Cutaneous squamous cell carcinoma of the head and neck with a finding of carcinoma in situ. (from AJCC 8th Ed.)


name: Grade 4 Cranial Nerve X Neuropathy, CTCAE


Other vitamin B12 deficiency anemias

description: Evidence of other vitamin B12 deficiency anemias not specified elsewhere.


Invasive Malignant Neoplasm

description: Cancer that has spread beyond the layer of tissue in which it developed and is growing into surrounding, healthy tissues.


Chief Complaint Present in the Morning

description: The chief complaint is noted to primarily occur in the period after sunrise and before noon.


name: Other Inflammatory Spondylopathies, Thoracolumbar Region

description: Evidence of other inflammatory spondylopathies in the thoracolumbar region not specified elsewhere.


name: Grade 4 Biliary Tree Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


name: Gestational Diabetes Mellitus in the Puerperium, Unspecified Control

description: Evidence of gestational diabetes mellitus in the puerperium with unspecified control.


Liver Cancer pN0 TNM Finding v7

description: Liver cancer with no regional lymph node metastasis. (from AJCC 7th Ed.)


name: Ovarian, Fallopian Tube, and Primary Peritoneal Carcinoma pT1b TNM Finding v8

description: Ovarian, fallopian tube, or primary peritoneal carcinoma with tumor limited to one or both ovaries (capsules intact) or fallopian tubes; no tumor on ovarian or fallopian tube surface; no malignant cells in ascites or peritoneal washings. (from AJCC 8th Ed.)


Uveal Melanoma pN1 TNM Finding v8

description: Uveal melanoma with regional lymph node metastasis or discrete tumor deposits in the orbit. (from AJCC 8th Ed.)


name: Chronic Myelomonocytic Leukemia with Eosinophilia

description: A chronic myelomonocytic leukemia characterized by a peripheral blood eosinophil count of equal or greater than 1.5x10E9/L, and absence of PDGFRA or PDGFRB gene abnormalities.


description: Marker study levels within normal limits. (AJCC 7th ed.)


name: Advanced Platinum-Resistant Malignant Germ Cell Tumor

description: A platinum-resistant malignant germ cell tumor that has spread extensively to other anatomic sites or is no longer responding to treatment.


Grade 3 Esophageal Obstruction, CTCAE

description: Hospitalization indicated; invasive intervention indicated; limiting self care ADL


name: Maxillary Sinus Cancer pN0 TNM Finding v6 and v7

description: Maxillary sinus cancer with no metastasis to regional lymph nodes. (from AJCC 6th and 7th Eds.)


name: Soft Tissue Sarcoma of the Trunk and Extremities pN0 TNM Finding v8

description: Soft tissue sarcoma of the trunk and extremities without regional lymph node metastasis or unknown lymph node status. (from AJCC 8th Ed.)


Grade 4 Ovarian Infection, CTCAE

description: Life-threatening consequences; urgent intervention indicated


name: Mycosis Fungoides and Sezary Syndrome N0 TNM Finding v8

description: No clinically abnormal peripheral lymph nodes; biopsy not required. Note: for node, abnormal peripheral lymph node(s) indicates any palpable peripheral node that on physical examination is firm, irregular, clustered, fixed or 1.5 cm or larger in diameter. Node groups examined on physical examination include cervical, supraclavicular, epitrochlear, axillary, and inguinal. Central nodes, which generally are not amenable to pathological assessment, currently are not considered in the nodal classification unless used to establish N3 histopathologically. (from AJCC 8th Ed.)


name: Ovarian, Fallopian Tube, and Primary Peritoneal Carcinoma pM1 TNM Finding v8

description: Ovarian, fallopian tube, or primary peritoneal carcinoma with distant metastasis, including pleural effusion with positive cytology; liver or splenic parenchymal metastasis; metastasis to extra-abdominal organs (including inguinal lymph nodes and lymph nodes outside the abdominal cavity); and transmural involvement of intestine. (from AJCC 8th Ed.)


name: Carcinoma of the Conjunctiva pN0 TNM Finding v7

description: Carcinoma of the conjunctiva with no regional lymph node metastasis. (from AJCC 7th Ed.)


name: Grade 2 Pelvis Infection NOS with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


name: Other Rheumatoid Arthritis with Rheumatoid Factor of Unspecified Elbow

description: Evidence of other rheumatoid arthritis with rheumatoid factor of unspecified elbow not specified elsewhere.


name: Stage IIIB Fallopian Tube Cancer AJCC v8

description: Stage IIIB includes: T3b, N0/N1, M0. T3b: Fallopian tube cancer with macroscopic peritoneal metastasis beyond pelvis 2 cm or less in greatest dimension with or without metastasis to the retroperitoneal lymph nodes. N0: No regional lymph node metastasis. N1: Positive retroperitoneal lymph nodes only (histologically confirmed). M0: No distant metastasis. (AJCC 8th Ed.)


name: Parathyroid Carcinoma pT3 TNM Finding v8

description: Tumor with direct invasion into recurrent laryngeal nerve, esophagus, trachea, skeletal muscle, adjacent lymph nodes, or thymus. (from AJCC 8th Ed.)


name: Grade 1 Ileum Intra-Operative Injury, CTCAE


name: Ampulla of Vater Invasive Papillary Adenocarcinoma

description: An invasive adenocarcinoma that arises from an exophytic papillary neoplasm of the ampulla of Vater.


name: Kidney Cancer Pathologic Distant Metastasis TNM Finding v6

description: A pathologic finding about one or more characteristics of kidney cancer, following the rules of the TNM AJCC v6 classification system as they pertain to distant metastases.


name: Esophagus and Esophagogastric Junction Cancer pT1 TNM Finding v8

description: Esophagus and esophagogastric junction cancer with tumor invading the lamina propria, muscularis mucosae, or submucosa. (from AJCC 8th Ed.)


name: Grade 5 External Ear Infection with Unknown Absolute Neutrophil Count, CTCAE


name: Malignant Neoplasm of Cortex of Left Adrenal Gland

description: Evidence of a malignant neoplasm of the cortex of left adrenal gland.


Stage IVC Appendix Carcinoma AJCC v7

description: Stage IVC includes: Any T, Any N, M1b, Any G.  M1b: Nonperitoneal metastasis.  (AJCC 7th ed.)


name: Grade 4 Lower Gastrointestinal Hemorrhage NOS, CTCAE


name: Unspecified Malignant Neoplasm of Skin of Left Upper Eyelid, Including Canthus

description: Evidence of unspecified malignant neoplasm of the skin of the left upper eyelid including the canthus.


PSA Level Less than Fifty

description: A blood concentration of prostate specific antigen less than or equal to 50 ng/mL.


name: Other Paralytic Syndrome following Other Non-Traumatic Intracranial Hemorrhage Affecting Left Non-Dominant Side

description: Evidence of other paralytic syndrome following other non-traumatic intracranial hemorrhage affecting left non-dominant side not specified elsewhere.


Colorectal Cancer TNM Finding v8

description: A finding about one or more characteristics of colorectal cancer, following the rules of the TNM AJCC v8 classification system. Adenocarcinomas, high-grade neuroendocrine carcinomas, and squamous cell carcinomas of the colon and rectum are covered by this staging system. Appendiceal carcinomas, anal carcinomas, and well-differentiated neuroendocrine tumors (carcinoids) are not covered by this staging system. (from AJCC 8th Ed.)


name: Unresectable Bladder Small Cell Neuroendocrine Carcinoma

description: Bladder small cell neuroendocrine carcinoma that is not amenable to surgical resection.


name: Grade 4 Liver Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


name: HPV-Mediated (p16-Positive) Oropharyngeal Cancer Clinical TNM Finding v8

description: A clinical finding about one or more characteristics of HPV-mediated (p16-positive) oropharyngeal cancer, following the rules of the TNM AJCC v8 classification system.


Grade 2 Myelitis, CTCAE

description: Moderate weakness or sensory loss; limiting instrumental ADL


name: Grade 3 Sinus Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


name: Cerebral Infarction due to Unspecified Occlusion or Stenosis of Left Middle Cerebral Artery

description: Evidence of cerebral infarction due to an unspecified occlusion or stenosis of the left middle cerebral artery.


name: Mucosal Melanoma of the Head and Neck pT3 TNM Finding v7

description: Mucosal melanoma of the head and neck with mucosal disease. (from AJCC 7th Ed.)


Repeat Expansion Disease

description: A class of genetic diseases that occur when microsatellite repeats expand beyond a threshold length.


name: Anal Adenocarcinoma within Anorectal Fistula

description: An anal adenocarcinoma arising from the lining of an anorectal fistulous tract.  The overlying anal mucosa does not show evidence of neoplastic changes.  Some cases are associated with Crohn disease.


Positive Dechallenge Response

description: Partial or complete abatement of an adverse event after decrease or change in dose, or withdrawal of the product/drug.


name: idiopathic normal pressure hydrocephalus

description: A disorder characterized by hydrocephalus in the setting of normal cerebrospinal fluid pressure, gait apraxia, impaired cognition and urinary urgency or incontinence.


Lyme Arthritis

description: Joint inflammation, most often affecting large joints, associated with Lyme disease, presenting months after infection.


name: Hemorrhage and Bleeding Associated with Surgery, CTCAE


name: Epileptic Spasms, not Intractable, with Status Epilepticus

description: Evidence of epileptic spasms with status epilepticus that responds to treatment.


Stage IA Cutaneous Melanoma AJCC v7

description: Stage IA includes: T1a, N0, M0.  T1a: Cutaneous melanoma with a tumor measuring 1.0 mm or less in thickness, without ulceration and with mitosis less than 1/mm2.  N0: No regional lymph node metastases.  M0: No detectable evidence of distant metastases. (from AJCC 7th Ed.)


Grade 3 Phantom Pain, CTCAE

description: Severe pain; limiting self care ADL


Grade 3 Abdominal Distension, CTCAE

description: Severe discomfort; limiting self care ADL


name: Stage IA Fallopian Tube Cancer AJCC v6 and v7

description: Stage IA includes: T1a, N0, M0. T1a: Tumor limited to one tube, without penetrating the serosal surface; no ascites.  N0: No regional lymph node metastasis.  M0: No distant metastasis. (AJCC 6th and 7th eds.)


name: Duodenum Infection with Unknown Absolute Neutrophil Count, CTCAE


Benign Infratentorial Neoplasms

description: A neoplasm that arises from the infratentorial region and is characterized by the absence of atypical or malignant cytological and architectural features, and absence of invasive features or metastatic potential.


name: Grade 4 Brain Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


Reiter's Disease, Left Shoulder

description: Evidence of Reiter's disease in the left shoulder.


name: Acute Lymphoblastic Leukemia by Gene Expression Profile

description: Gene expression-based patient cluster groups in acute lymphoblastic leukemia.


name: Grade 1 Vagina Stricture or Stenosis, CTCAE


Grade 5 Peripheral Ischemia, CTCAE

description: Death


name: Cranial Nerve Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


name: alcohol dependence with withdrawal - uncomplicated

description: Evidence of alcohol dependence with withdrawal, uncomplicated.


Doesn't Meet Abnormal Standards

description: A result that does not meet the threshold to be interpreted as abnormal.


name: Head and Neck Cancer Clinical Regional Lymph Nodes TNM Finding v8

description: A clinical finding about one or more characteristics of head and neck cancer, following the rules of the TNM AJCC v8 classification system as they pertain to staging of regional lymph nodes.


Grade 5 Alkalosis, CTCAE

description: Death


name: Drug or Chemical Induced Diabetes Mellitus with Proliferative Diabetic Retinopathy with Traction Retinal Detachment not Involving the Macula, Bilateral

description: Evidence of drug or chemical induced diabetes mellitus with proliferative diabetic retinopathy with traction retinal detachment not involving the macula that is bilateral.


name: Malignant Neoplasm of Right Lacrimal Gland and Duct

description: Evidence of a malignant neoplasm of the right lacrimal gland and duct.


Composite paraganglioma

description: A neoplasm that combines morphologic characteristics of paraganglioma and neuroectodermal tumors such as neuroblastoma, ganglioneuroma, ganglioneuroblastoma, or peripheral nerve sheath tumor.


name: Grade 2 Glomerular Filtration Rate, CTCAE


Recurrent pyogenic cholangitis

description: A recurrent form of cholangitis that is characterized by intrabiliary pigment stone formation, biliary tree stricture and obstruction, and recurrent bouts of cholangitis. There is an association with biliary parasitosis, but evidence supporting these infections in the pathogenesis of recurrent pyogenic cholangitis is inconclusive. The most common causes of death are sepsis, liver failure, or complications from cirrhosis. Patients are also at increased risk of cholangiocarcinoma.


Grade 3 Pharyngeal Stenosis, CTCAE

description: Limiting self care ADL; stridor; endoscopic intervention indicated (e.g., stent, laser)


name: Grade 3 Lower Extremity Vein Intra-Operative Injury, CTCAE


name: Stage II Ampulla of Vater Cancer AJCC v8

description: Stage II includes: IIA: T3a, N0, M0; IIB: T3b, N0, M0. T3a: Tumor directly invading the pancreas (up to 0.5 cm). T3b: Tumor extending more than 0.5 cm into the pancreas, or extending into peripancreatic tissue or duodenal serosa without involvement of the celiac axis or superior mesenteric artery. N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 8th ed.)


Bone lesion

description: A localized pathological or traumatic structural change, damage, deformity, or discontinuity of bone.


name: Germinative Follicular Epithelium Neoplasm

description: A neoplasm involving the germinative follicular epithelium.


name: Infectious disease of genitourinary system

description: An acute or chronic infectious process affecting any part of the genitourinary system.


Complication of transplanted lung

description: A disease or disorder that is associated with a transplanted lung.


name: Grade 1 Urinary Electrolyte Wasting, CTCAE


name: Lung Cancer Pathologic Regional Lymph Nodes TNM Finding v8

description: A pathologic finding about one or more characteristics of lung cancer, following the rules of the TNM AJCC v8 classification system as they pertain to staging of regional lymph nodes.


name: Myeloid/Lymphoid Neoplasms with ETV6-ABL1

description: Hematologic neoplasms characterized by t(9;12)(q34.1;p13.2) that results in ETV6-ABL1 gene fusion. They have clinicopathological features of chronic myeloid leukemia with frequent eosinophilia.


name: Gastric Neuroendocrine Tumor pM1 TNM Finding v7

description: Gastric neuroendocrine tumor with distant metastasis. (from AJCC 7th Ed.)


Grade 4 Pancreatic Hemorrhage, CTCAE

description: Life-threatening consequences; urgent intervention indicated


Mixed Failure to Thrive

description: Failure to thrive due to both organic and non-organic causes.


name: Esophagus and Esophagogastric Junction Cancer Clinical TNM Finding v8

description: A clinical finding about one or more characteristics of esophagus and esophagogastric junction cancer, following the rules of the TNM AJCC v8 classification system.


description: Evidence of moderate persistent asthma with status asthmaticus.


Dysgeusia, CTCAE

description: A disorder characterized by abnormal sensual experience with the taste of foodstuffs; it can be related to a decrease in the sense of smell.


name: Lymphoblastic Diffuse Lymphoma, Lymph Nodes of Inguinal Region and Lower Limb

description: Evidence of lymphoblastic diffuse lymphoma in the lymph nodes of inguinal region and lower limb.


Aneurysm of leg artery

description: Evidence of aneurysm of artery of lower extremity.


name: Grade 1 Urinary Tract NOS Intra-Operative Injury, CTCAE


PSA Level Finding

description: A finding that indicates the amount of prostate specific antigen in a sample.


Wound Complication, CTCAE

description: A finding of development of a new problem at the site of an existing wound.


name: Parathyroid Carcinoma pT4 TNM Finding v8

description: Tumor with direct invasion into major blood vessel or spine. (from AJCC 8th Ed.)


name: Grade 5 Brain and Spinal Cord Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


name: Grade 4 Fever Without Neutropenia, CTCAE


name: Burkitt lymphoma in extranodal and solid organ sites

description: Evidence of Burkitt lymphoma in the extranodal and solid organ sites.


Grade 1 Dry Skin, CTCAE

description: Covering <10% BSA and no associated erythema or pruritus


name: Childhood Malignant Digestive System Neoplasm

description: A malignant neoplasm that affects any part of the digestive system and occurs during childhood.


name: Stage IV Lentigo Maligna Melanoma AJCC v6 and v7

description: Stage IV includes: (Any T, Any N, M1).  M1: Distant metastasis. (from AJCC 6th and 7th Eds.)


name: Grade 1 Other Growth and Development, CTCAE


name: Rheumatoid Arthritis of Left Hand with Involvement of Organs and Systems

description: Evidence of rheumatoid arthritis of left hand with involvement of organs and systems.


name: Nasal Cavity and Ethmoid Sinus Cancer pT4b TNM Finding v8

description: Nasal cavity and ethmoid sinus cancer with very advanced local disease. Tumor invades any of the following: orbital apex, dura, brain, middle cranial fossa, cranial nerves other than maxillary division of trigeminal nerve (V2), nasopharynx, or clivus. (from AJCC 8th Ed.)


name: Thyroid Cancer pTX TNM Finding v6 and v7

description: Thyroid cancer in which the primary tumor cannot be assessed. (from AJCC 6th and 7th Eds.)


name: Unspecified Malignant Neoplasm Skin of Left Eyelid, Including Canthus

description: Evidence of unspecified malignant neoplasm skin of the left eyelid including the canthus.


name: Melanoma of the Conjunctiva pT2a TNM Finding v7

description: Melanoma of the palpebral, forniceal, or caruncular conjunctiva with tumor measuring not more than 0.5 mm in thickness with invasion of the substantia propria.  (from AJCC 7th Ed.)


Hypothalamic Cancer

description: A primary or metastatic malignant neoplasm that affects the hypothalamus.


Hypergranular promyelocytic leukemia

description: Acute Promyelocytic leukemia characterized by the presence of hypergranular promyelocytes and characteristic cells that contain bundles of Auer rods.


Grade 2 Oropharyngeal Pain, CTCAE

description: Moderate pain; altered oral intake; non-narcotics initiated; topical analgesics initiated


name: Grade 4 Vagina Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


Grade 4 Cholesterol High, CTCAE

description: >500 mg/dL; >12.92 mmol/L


Appendiceal Cancer TNM Finding v8

description: A finding about one or more characteristics of appendiceal cancer, following the rules of the TNM AJCC v8 classification system. Carcinomas and well-differentiated neuroendocrine tumors (carcinoids) are separately categorized. (from AJCC 8th Ed.)


Grade 1 Pulmonary Valve Disease, CTCAE

description: Asymptomatic valvular thickening with or without mild valvular regurgitation or stenosis by imaging


name: Non-Hodgkin's Lymphoma, Lymphoblastic (WF)


name: Drug or Chemical Induced Diabetes Mellitus with Other Diabetic Ophthalmic Complication

description: Evidence of drug or chemical induced diabetes mellitus with other diabetic ophthalmic complication.


Acute duodenal ulcer with hemorrhage

description: Evidence of an acute duodenal ulcer with hemorrhage.


name: Grade 3 Intraoperative Hepatobiliary Injury, CTCAE

description: Complete resection or reconstruction of injured organ/structure indicated; limiting self care ADL


Grade 5 Cystitis Noninfective, CTCAE

description: Death


Grade 4 Enterocolitis Infectious, CTCAE

description: Life-threatening consequences; urgent intervention indicated


Solder Fume Exposure

description: Environmental, occupational, or consumer-based exposure to vaporized materials during the soldering process.


name: Pre-Existing Hypertensive Heart and Chronic Kidney Disease Complicating Pregnancy, Unspecified Trimester

description: Evidence of pre-existing hypertensive heart and chronic kidney disease complicating pregnancy in an unspecified trimester.


name: Grade 4 Prolapse of Gastrointestinal Stoma, CTCAE


Stage IVB Gallbladder Cancer AJCC v8

description: Stage IVB includes: (Any T, N2, M0); (Any T, Any N, M1). N2: Metastases to four or more regional lymph nodes. M0: No distant metastasis. M1: Distant metastasis. (AJCC 8th ed.)


name: Locally Advanced Bladder Small Cell Neuroendocrine Carcinoma

description: A bladder small cell neuroendocrine carcinoma that has spread from its original site of growth to nearby tissues or lymph nodes.


name: Primary cutaneous CD30 antigen positive T-cell lymphoproliferative disorder

description: A spectrum of lymphoproliferative disorders characterized by CD30 (Ki-1)-positive cutaneous T-cell infiltrates. The two ends of the spectrum include lymphomatoid papulosis and primary cutaneous anaplastic large cell lymphoma.


name: Head and Neck Cancer pN2c TNM Finding v8

description: Head and neck cancer with metastases in bilateral or contralateral lymph nodes, none larger than 6 cm in greatest dimension and ENE(-). (from AJCC 8th Ed.)


name: Grade 2 Esophagus Intra-Operative Injury, CTCAE


BRCA2 Gene Mutation Negative

description: A genetic finding indicating that BRCA2 gene mutations have not been detected in a sample.


name: Malignant Neoplasm of Upper-Outer Quadrant of Unspecified Male Breast

description: Evidence of a malignant neoplasm of the upper-outer quadrant of unspecified male breast.


name: Other Dermatomyositis, Organ Involvement Unspecified

description: Evidence of other dermatomyositis, organ involvement unspecified not specified elsewhere.


CD36 Negative

description: An indication that CD36 expression has not been detected in a sample.


Dyspnea with Moderate Physical Activity

description: Dyspnea experienced during moderate exertion.


name: Uterine Corpus Adenosarcoma pT0 TNM Finding v8

description: Uterine corpus adenosarcoma with no evidence of primary tumor. (from AJCC 8th Ed.)


name: Localized Childhood Undifferentiated High Grade Pleomorphic Sarcoma of Bone

description: An undifferentiated high grade pleomorphic sarcoma of bone that occurs in childhood and has not spread to other anatomic sites.


Grade 3 Hematuria, CTCAE

description: Gross hematuria; transfusion, IV medications, or hospitalization indicated; elective invasive intervention indicated; limiting self care ADL


Grade 1 Fall, CTCAE

description: Minor with no resultant injuries; intervention not indicated


Soft Tissue Sarcoma cM1 TNM Finding v7

description: Soft tissue sarcoma with distant metastasis. (from AJCC 7th Ed.)


name: Nasal Cavity and Paranasal Sinuses Cancer pN1 TNM Finding v8

description: Nasal cavity and paranasal sinuses cancer with metastasis in a single ipsilateral lymph node, 3 cm or smaller in greatest dimension and ENE(-). (from AJCC 8th Ed.)


name: Locally Advanced Pancreatic Neuroendocrine Carcinoma

description: A pancreatic neuroendocrine carcinoma that has spread from its original site of growth to nearby tissues or lymph nodes.


Unresectable Oligodendroglioma

description: An oligodendroglioma that is not amenable to surgical resection.


name: Conjunctival Carcinoma Clinical TNM Finding v8

description: A clinical finding about one or more characteristics of conjunctival carcinoma, following the rules of the TNM AJCC v8 classification system.


name: Grade 2 Nodal or Junctional Rhythm, CTCAE


name: Grade 3 Uterus Infection with Unknown Absolute Neutrophil Count, CTCAE


name: Stage IA Childhood Hodgkin Lymphoma by Toronto Guidelines v2

description: Involvement of a single lymph node region or involvement of a single extra-lymphatic organ or site, without lymph node involvement. No constitutional symptoms are recorded. This definition applies to both tiers (tier 1 and 2). (Childhood cancer staging for population registries according to the Toronto Childhood Cancer Stage Guidelines - Version 2. Cancer Council Queensland and Cancer Australia: Brisbane, Australia; 2021.)


name: Uterine Corpus Adenosarcoma pNX TNM Finding v8

description: Uterine corpus adenosarcoma in which the regional lymph nodes cannot be assessed. (from AJCC 8th Ed.)


name: Yolk Sac Tumor with Somatic-Type Malignancy

description: A yolk sac tumor that is characterized by morphologic transformation to somatic-type malignancy. The somatic-type malignant component most often is sarcomatous or carcinomatous.


name: Atherosclerosis of Autologous Vein Bypass Graft(s) of the Left Leg with Ulceration of Ankle

description: Evidence of atherosclerosis of autologous vein bypass graft(s) of the left leg with ulceration of ankle.


name: Grade 4 Atrial Tachycardia or Paroxysmal Atrial Tachycardia, CTCAE


name: Clear Cell Tumor with Melanocytic Differentiation and MITF-CREM Translocation

description: A MITF pathway-activated melanocytic tumor characterized by a cytogenetic translocation between MITF and CREM genes that results in MITF-CREM gene fusion. It presents as a single non-pigmented cutaneous nodule in the distal extremities. It is composed of large cells with clear cytoplasm that exhibit melanocytic differentiation and proliferate in the dermis without an intraepidermal component. Extension in the subcutaneous tissue is frequently seen. The neoplastic cells exhibit atypical features, including nuclear enlargement and hyperchromasia, irregular nuclear borders, and enlarged nucleolus. Mitotic activity is prominent. The biologic potential of this tumor is unknown.


name: Absence Epileptic Syndrome, not Intractable, with Status Epilepticus

description: Evidence of absence epileptic syndrome with status epilepticus that responds to treatment.


name: Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


name: Rheumatoid Heart Disease with Rheumatoid Arthritis of Left Hip

description: Evidence of rheumatoid heart disease with rheumatoid arthritis of left hip.


Intraepithelial Melanocytic Hyperplasia

description: A hyperplasia of the intraepithelial melanocytes.


name: Grade 1 Stomach Stricture or Stenosis, CTCAE


name: FIGO Stage IVC Gestational Trophoblastic Tumor