Stage I Bone Cancer AJCC v7

description: Stage I includes: IA (T1, N0, M0, G1, G2, GX); IB (T2, N0, M0, G1, G2, GX); (T3, N0, M0, G1, G2, GX).  T1: Tumor 8 cm or less in greatest dimension.  T2: Tumor more than 8 cm in greatest dimension.  T3: Discontinuous tumors in the primary bone site.  N0: No regional lymph node metastasis.  M0: No distant metastasis.  G1: Well differentiated-low grade.  G2: Moderately differentiated-low grade.  GX: Grade cannot be assessed. (AJCC 7th ed.)


Patient Condition Undetermined

category: biolink:PhenotypicFeature biolink:DiseaseOrPhenotypicFeature biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing

description: An indication that the patient’s condition is undetermined.


Subchronic latent schizophrenia

category: biolink:Disease biolink:DiseaseOrPhenotypicFeature biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing


name: Gestational Trophoblastic Neoplasm cM1b TNM Finding v8

description: Gestational trophoblastic neoplasm with all other distant metastases. (from AJCC 8th Ed.)


name: Grade 1 Leukoencephalopathy Radiographic Findings, CTCAE


HER2/Neu Negative by FISH

description: A laboratory test result indicating the absence of HER2/Neu in a tissue sample using fluorescence in situ hybridization.


Metastatic malignant neoplasm to retina

description: A malignant neoplasm that has spread to the retina from another anatomic site.


Stage IVB Uterine Corpus Cancer AJCC v7

description: Stage IVB includes: Any T, Any N, M1.  M1: Distant metastasis (includes metastasis to inguinal lymph nodes, intraperitoneal disease, or lung, liver, or bone.  It excludes metastasis to para-aortic lymph nodes, vagina, pelvic serosa, or adnexa). This staging applies to carcinomas and carcinosarcomas. (AJCC 7th ed.)


Stage IB3 Cervical Cancer FIGO 2018

description: Invasive cervical carcinoma equal or more than 4 cm in greatest dimension. (FIGO 2018)


Supraglottic Cancer pMX TNM Finding v6

description: Supraglottic cancer in which distant metastasis cannot be assessed. (from AJCC 6th Ed.)


Cutaneous Mature B-Cell Neoplasm

description: A mature B-cell neoplasm that affects the skin.


name: Grade 3 Muscle Infection with Unknown Absolute Neutrophil Count, CTCAE


Iris Melanoma pT3 TNM Finding v8

description: Iris melanoma with tumor confluent with or extending into the ciliary body, choroid, or both, with scleral extension. (from AJCC 8th Ed.)


name: Grade 5 Spleen Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


name: Nasopharyngeal Cancer pTis TNM Finding v8

description: Nasopharyngeal cancer with a finding of carcinoma in situ. (from AJCC 8th Ed.)


Prostate Melanoma

description: An exceptionally rare melanoma arising from the prostate gland.


name: Grade 3 Retinal Vascular Disorder, CTCAE

description: Retinal vascular disorder with neovascularization


Deep Lipoma

description: A benign well-circumscribed tumor, composed of mature adipocytes, that arises within deep soft tissues.


Craniofacial Fibrous Dysplasia

description: Fibrous dysplasia affecting the craniofacial bones.


name: Diabetes mellitus type 2 with periodontal disease

description: Evidence of type 2 diabetes mellitus with periodontal disease.


name: Exocrine Pancreatic Cancer Pathologic Regional Lymph Nodes TNM Finding v8

description: A pathologic finding about one or more characteristics of exocrine pancreatic cancer, following the rules of the TNM AJCC v8 classification system as they pertain to staging of regional lymph nodes.


name: Grade 5 Upper Aerodigestive Infection NOS with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


name: Other Specified Rheumatoid Arthritis, Unspecified Hip

description: Evidence of other specified rheumatoid arthritis in an unspecified hip not specified elsewhere.


name: Grade 3 Muscular and Skeletal Hypoplasia, CTCAE


name: Grade 2 Joint Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


Cardiac granuloma

description: A granuloma located in the myocardium.


name: Stage III Childhood Malignant Kidney Neoplasm Excluding Renal Cell Carcinoma by Toronto Guidelines v2, Children's Oncology Group (COG) Protocol

description: Residual tumor or nonhematogenous metastases confined to abdomen. Involved abdominal nodes. Peritoneal contamination or tumor implant. Tumor spillage of any degree occurring before or during surgery. Gross residual tumor in abdomen. Biopsy of tumor (including fine-needle aspiration) prior to removal of kidney. Resection margins involved by tumor. (Childhood cancer staging for population registries according to the Toronto Childhood Cancer Stage Guidelines - Version 2. Cancer Council Queensland and Cancer Australia: Brisbane, Australia; 2021.)


name: Uveal Melanoma Pathologic Regional Lymph Nodes TNM Finding v8

description: A pathologic finding about one or more characteristics of uveal melanoma, following the rules of the TNM AJCC v8 classification system as they pertain to staging of regional lymph nodes.


name: Grade 3 Pancreatic Duct Intra-Operative Injury, CTCAE


Grade 2 Proctitis, CTCAE

description: Symptomatic (e.g., rectal discomfort, passing blood or mucus); medical intervention indicated; limiting instrumental ADL


name: Persistent Pulmonary Hypertension of the Newborn, AE

description: An adverse event in a newborn characterized by elevated pulmonary vascular pressure in a neonate.


name: Grade 5 Mediastinum Infection NOS with Unknown Absolute Neutrophil Count, CTCAE


name: Grade 4 Upper Aerodigestive Infection NOS Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


Elevated DKK1

description: A finding indicating elevated concentrations of DKK1 in a sample.


Malignant Neoplasm of Left Optic Nerve

description: Evidence of a malignant neoplasm of the left optic nerve.


Grade 5 Cecal Infection, CTCAE

description: Death


name: manic episode without psychotic symptoms - mild

description: Evidence of manic episode without psychotic symptoms, mild.


name: Post-Dysenteric Arthropathy, Right Shoulder

description: Evidence of post-dysenteric arthropathy in the right shoulder.


Neonatal Spell

description: Cardiorespiratory events that are characterized by variable combinations of cessation of breathing, decrease in blood oxygen saturation, and decreased heart rate.


Stage IIA Esophagus Carcinoma

description: Stage IIA includes: For squamous cell carcinoma: (T2-3, N0, M0, G1, GX, Tumor location: Upper, middle); (T2-3, N0, M0, G2-3, Tumor location: Lower, X).  For adenocarcinoma: (T2, N0, M0, G3).  T2: Tumor invades muscularis propria. T3: Tumor invades adventitia.  N0: No regional lymph node metastasis.  M0: No distant metastasis.  G1: Well differentiated.  GX: Grade cannot be assessed-stage grouping as G1.  G2: Moderately differentiated.  G3: Poorly differentiated.  Tumor location: Location of the primary cancer site is defined by the position of the upper (proximal) edge of the tumor in the esophagus.  (AJCC 7th ed.)


name: Grade 4 Ovary Intra-Operative Injury, CTCAE


name: Mucositis and Stomatitis by Functional and Symptomatic Classification, CTCAE


Leukopenia neonatal

description: Leukopenia that occurs in the neonatal period.


Acute lymphoblastic leukemia recurrent

description: The reemergence of acute lymphoblastic leukemia after a period of remission.


name: Unresectable Small Cell Neuroendocrine Carcinoma

description: Small cell neuroendocrine carcinoma that is not amenable to surgical resection.


Pancreatic intraepithelial neoplasia

description: A pre-cancerous, non-invasive pancreatic epithelial neoplasm that arises from and is confined to the pancreatic ducts.  It is a papillary or flat neoplasm that usually measures less than 5 mm in diameter.


name: Major Salivary Gland Cancer pM1 TNM Finding v6 and v7

description: Major salivary gland cancer with distant metastasis. (from AJCC 6th and 7th Eds.)


name: Conjunctival Melanoma Pathologic Primary Tumor TNM Finding v8

description: A pathologic finding about one or more characteristics of conjunctival melanoma, following the rules of the TNM AJCC v8 classification system as they pertain to staging of the primary tumor.


Esophageal Cancer by AJCC v8 Stage

description: A term that refers to the staging of esophageal carcinoma according to the American Joint Committee on Cancer, 8th edition.


Nodular Opacity

description: A radiologic finding indicating the presence of a solitary, round, circumscribed shadow in the lung on chest x-ray.


name: Stage IIIB Merkel Cell Carcinoma AJCC v7

description: Stage IIIB includes: Any T, N1b/N2, M0.  N1b: Macrometastasis in regional lymph nodes.  N2: In transit metastasis.  M0: No distant metastasis.  (AJCC 7th Ed.)


Recurrent Myeloproliferative Neoplasm

description: The reemergence of a myeloproliferative neoplasm after a period of remission.


Burn of axilla

description: A traumatic injury to the axilla resulting from exposure to caustic chemicals, extreme heat, extreme cold, or excessive radiation.


Grade 3 Hematosalpinx, CTCAE

description: Transfusion indicated; invasive intervention indicated


Bladder Infection, CTCAE

description: A disorder characterized by an infectious process involving the bladder.


name: Sézary's disease of lymph nodes of inguinal region and lower limb

description: Evidence of Sezary disease in the lymph nodes of inguinal region and lower limb.


pT3a TNM Finding

description: A pathologic primary tumor TNM finding. The definition of pT3a finding depends on the particular type of cancer that it refers to; for example, for cervical cancer, pT3a finding is defined as follows: cancer involves lower third of vagina, without extension to pelvic wall; for kidney cancer, pT3a finding is defined as follows: cancer with tumor grossly extending into the renal vein or its segmental (muscle containing) branches or tumor invading perirenal and/or renal sinus fat but not beyond Gerota's fascia. (from AJCC 7th Ed.)


name: Nasal Cavity and Ethmoid Sinus Cancer pT2 TNM Finding v8

description: Nasal cavity and ethmoid sinus cancer with tumor invading two subsites in a single region or extending to involve an adjacent region within the nasoethmoidal complex, with or without bony invasion. (from AJCC 8th Ed.)


name: Occlusion and Stenosis of Unspecified Middle Cerebral Artery

description: Evidence of occlusion and stenosis of unspecified middle cerebral artery.


Adverse Event Attributed to Disease

description: An indication that an adverse event is causally related to the natural history of disease.


ATRX Negative

description: An indication that ATRX expression has not been detected in a sample.


Grade 2 Mucositis Oral, CTCAE

description: Moderate pain or ulcer that does not interfere with oral intake; modified diet indicated


name: Maxillary Sinus Cancer pN1 TNM Finding v6 and v7

description: Maxillary sinus cancer with metastasis to a single ipsilateral lymph node, 3 cm or less in greatest dimension. (from AJCC 6th and 7th Eds.)


Grade 5 Arteritis Infective, CTCAE

description: Death


name: Small Intestine Cancer pT4 TNM Finding v7

description: Small intestine cancer with tumor perforating the visceral peritoneum or directly invading other organs or structures (including other loops of small intestine, mesentery, or retroperitoneum more than 2 cm, and abdominal wall by way of serosa; for duodenum only, invasion of pancreas or bile duct). (from AJCC 7th Ed.)


Acute Rejection

description: Rejection of a transplanted organ that usually occurs after the first week of the transplantation.  The risk of acute rejection is highest in the first three months following transplantation.  Morphologically, there is an inflammatory infiltrate composed of lymphocytes and neutrophils and vascular damage in the rejected tissue.


secondary carcinoid tumor of liver

description: Evidence of secondary carcinoid tumors of liver.


name: Anal or Perianal Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


Other iron deficiency anemias

description: Evidence of other iron deficiency anemias not specified elsewhere.


name: Grade 5 Pancreatic Endocrine Glucose Intolerance, CTCAE


Mucopurulent chronic bronchitis

description: Evidence of mucopurulent chronic bronchitis.


Sexual Aversion Disorder

description: A disorder characterized by recurrent or persistent extreme aversion to, and avoidance of, all genital contact with a sexual partner. The aversion to sexual contact is not attributable to another psychiatric disorder.


Gallbladder Tubular Carcinoid

description: A neuroendocrine tumor that arises from the gallbladder.  It does not show the morphologic characteristics of typical carcinoid tumors (neoplastic cells forming solid nests). In contrast, the tumor cells form small discrete tubules.


name: Grade 2 Breast Volume and Hypoplasia, CTCAE


name: Grade 3 Intraoperative Gastrointestinal Injury, CTCAE

description: Complete resection or reconstruction of injured organ/structure indicated; limiting self care ADL


name: Malignant Neoplasm of Right Kidney, Except Renal Pelvis

description: Evidence of a malignant neoplasm of the right kidney, except renal pelvis.


name: Grade 2 Small Intestinal Mucositis, CTCAE

description: Symptomatic; medical intervention indicated; limiting instrumental ADL


Benign Thymoma

description: A thymoma that is completely surrounded by a capsule, without evidence of capsular invasion, infiltration of the surrounding tissues, and metastases.


name: Testicular Cancer Clinical Distant Metastasis TNM Finding v7

description: A clinical finding about one or more characteristics of testicular cancer, following the rules of the TNM AJCC v7 classification system as they pertain to distant metastases.


name: Cutaneous Melanoma by AJCC v8 Clinical Stage

description: A term that refers to the clinical staging of cutaneous melanoma, following the rules of the TNM AJCC v8 classification system.


name: malignant carcinoid tumor of other sites

description: Evidence of a malignant carcinoid tumors of other sites.


name: Conjunctival Melanoma Clinical Distant Metastasis TNM Finding v8

description: A clinical finding about one or more characteristics of conjunctival melanoma, following the rules of the TNM AJCC v8 classification system as they pertain to distant metastases.


Chief Complaint Intermittently Present

description: The chief complaint intermittently stops then starts again.


name: Grade 4 Cornea Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


name: Gallbladder Cancer pTis TNM Finding v6 and v7

description: Gallbladder cancer with a finding of carcinoma in situ. (from AJCC 6th and 7th Eds.)


Posttherapy Clinical TNM Finding

description: Clinical TNM staging performed following systemic therapy or radiation.


name: Retinoblastoma Pathologic Regional Lymph Nodes TNM Finding v8

description: A pathologic finding about one or more characteristics of retinoblastoma, following the rules of the TNM AJCC v8 classification system as they pertain to staging of regional lymph nodes.


Grade 3 Proctitis, CTCAE

description: Severe symptoms; fecal urgency or stool incontinence; limiting self care ADL


name: Infection and Inflammation Reaction due to Cardiac Valve Prosthesis, Sequela

description: Evidence of infection and inflammation reaction due to cardiac valve prosthesis, sequela.


name: Type 1 Diabetes Mellitus with Mild Nonproliferative Diabetic Retinopathy with Macular Edema, Bilateral

description: Evidence of type 1 diabetes mellitus with mild nonproliferative diabetic retinopathy with macular edema that is bilateral.


name: Oropharyngeal (p16-Negative) Cancer Pathologic Distant Metastasis TNM Finding v8

description: A pathologic finding about one or more characteristics of oropharyngeal (p16-negative) cancer, following the rules of the TNM AJCC v8 classification system as they pertain to distant metastases.


Grade 3 Vaginal Perforation, CTCAE

description: Invasive intervention indicated


Childhood Osteoid Osteoma

description: An osteoid osteoma that occurs during childhood.


Grade 2 Lymph Leakage, CTCAE

description: Symptomatic; medical intervention indicated


name: Secondary Malignant Neoplasm of Other Respiratory Organs

description: Evidence of secondary malignant neoplasm of other respiratory organs.


Grade 4 Nephrotic Syndrome, CTCAE

description: Life-threatening consequences; urgent intervention indicated


Stage IA Cervical Cancer FIGO 2009

description: Cervical carcinoma measuring equal or less than 5 mm in depth and equal or less than 7 mm in width. (FIGO 2009)


Primary Valvular Disorder

description: Heart disease that is primarily due to a valvular defect or abnormality. Valve disease that is felt to be significant but does not fulfill the definition for primary valvular heat disease is considered contributory valvular heart disease.


name: Grade 3 Genitourinary Stoma Obstruction, CTCAE


name: Rheumatic Disorders of Both Mitral and Aortic Valves

description: Evidence of rheumatic disorders of both mitral and aortic valves.


Merkel Cell Carcinoma by AJCC v7 Stage

description: A term that refers to the staging of Merkel cell carcinoma (primary cutaneous neuroendocrine carcinoma), following the rules of the TNM AJCC v7 classification system.


Incidental Lesion Finding

description: An asymptomatic benign or malignant lesion discovered during an endoscopic, surgical, or radiologic procedure performed for unrelated reasons.


Complication of transplanted organ, NOS

description: A disease or disorder that is associated with a transplanted organ.


Prostate Cancer cT2b TNM Finding v7

description: Prostate cancer with tumor involving more than one-half of one lobe, but not both lobes. (from AJCC 7th Ed.)


name: Cerebral Infarction due to Unspecified Occlusion or Stenosis of Unspecified Middle Cerebral Artery

description: Evidence of cerebral infarction due to an unspecified occlusion or stenosis of an unspecified middle cerebral artery.


Grade 2 Hallucinations, CTCAE

description: Moderate hallucinations


name: Ocular Adnexal Lymphoma pT4 TNM Finding v7

description: Orbital adnexal lymphoma extending beyond orbit to adjacent structures such as bone and brain.  (from AJCC 7th Ed.)


name: Embolism and thrombosis of arteries of upper extremities

description: Evidence of embolism and thrombosis of arteries of the upper extremities.


name: Childhood Benign Nervous System Neoplasm

description: A childhood neoplasm that arises from the nervous system and is characterized by the absence of atypical or malignant cytological and architectural features, and absence of invasive features or metastatic potential.


name: Atherosclerosis of Non-Autologous Biological Bypass Graft(s) of Right Leg with Ulceration of Other Part of Lower Leg

description: Evidence of atherosclerosis of non-autologous biological bypass graft(s) of right leg with ulceration of other part of lower leg.


name: PSA Level Greater than 0 but Less than 0.2

description: A blood concentration of prostate specific antigen greater than 0 and less than 0.2 ng/mL.


Thrombosis of vena cava

description: The formation of a thrombus in the vena cava.


name: Grade 3 Serum Hypertriglyceridemia, CTCAE


name: Grade 5 Nervous System Disorders - Other, Specify, CTCAE

description: Death


name: Opportunistic Infection Associated with Grade 2 or Greater Lymphopenia, CTCAE


Grade 2 Pain of Skin, CTCAE

description: Moderate pain; limiting instrumental ADL


name: Cutaneous Follicular Center Lymphoma, Lymph Nodes of Axilla and Upper Limb

description: Evidence of cutaneous follicular center lymphoma in the lymph nodes of axilla and upper limb.


name: Pelvic Undifferentiated High Grade Pleomorphic Sarcoma

description: Undifferentiated high grade pleomorphic sarcoma  involving the bones of the pelvis.


Marasmic kwashiorkor

description: Evidence of marasmic kwashiorkor.


name: Grade 2 Cranial Nerve Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


name: Skin Squamous Cell Carcinoma or Other Skin Carcinomas pN2a TNM Finding v7

description: Skin squamous cell carcinoma or other skin carcinomas with metastasis in a single ipsilateral lymph node, more than 3 cm but not more than 6 cm in greatest dimension. (from AJCC 7th Ed.)


Chronic Orthostatic Intolerance

description: A condition in which there is orthostatic intolerance lasting for at least three months with associated functional impairment. (ACC/AHA)


M1b TNM Finding

description: A TNM finding indicating the spread of cancer to distant anatomic sites.  The definition of M1b TNM finding depends on the specific type of cancer that it refers to; for example, for colorectal cancer it refers to metastases in more than one organ/site or the peritoneum; for prostate cancer it refers to metastasis to bone(s); for bone cancer it refers to metastasis to distant sites other than lung.


Renal hemangioma

description: A rare hemangioma arising from the kidney.


name: Conjunctival Melanoma pN0 TNM Finding v8

description: Conjunctival melanoma with no regional lymph node metastasis. (from AJCC 8th Ed.)


name: Atherosclerosis of Autologous Vein Bypass Graft(s) of the Left Leg with Ulceration of Calf

description: Evidence of atherosclerosis of autologous vein bypass graft(s) of the left leg with ulceration of calf.


Grade 3 Scrotal Pain, CTCAE

description: Severe pain; limiting self care ADL


name: Arthropathy following Intestinal Bypass, Left Wrist

description: Evidence of arthropathy following intestinal bypass in the left wrist.


description: Evidence of cocaine abuse with cocaine-induced mood disorder.


name: Perihilar Bile Duct Cancer TNM Finding v8

description: A finding about one or more characteristics of perihilar bile duct cancer, following the rules of the TNM AJCC v8 classification system. This staging system applies to perihilar cholangiocarcinomas. Well-differentiated neuroendocrine tumors and sarcomas are not staged using this staging system. (from AJCC 8th Ed.)


name: FIGO Grade 2 Endometrioid Adenocarcinoma

description: Endometrioid adenocarcinoma exhibiting 6-50% solid non-glandular, non-squamous growth.


name: Recurrent Malignant Urinary System Neoplasm

description: Reemergence of a malignant urinary system neoplasm after a period of remission.


Grade 4 Hyperphosphatemia, CTCAE

description: Life-threatening consequences; urgent intervention indicated (e.g., dialysis)


name: Grade 5 Pancreas or Pancreatic Duct Stricture or Stenosis, CTCAE


name: Grade 1 Thyroid Stimulating Hormone Increased, CTCAE

description: TSH increased and no intervention initiated


Vaginal Cancer pT1b TNM Finding v8

description: Vaginal cancer with tumor confined to the vagina, measuring more than 2.0 cm. (from AJCC 8th Ed.)


Iron deficiency without anemia

description: Subnormal concentrations of iron resulting from low iron intake, inefficient iron absorption in the gastrointestinal tract, or increased iron loss; occurring in the absence of anemia.


name: Stage I Esophageal Adenocarcinoma AJCC v7

description: Stage I includes: IA (T1, N0, M0, G1-2, X); IB (T1, N0, M0, G3); (T2, N0, M0, G1-2, GX).  T1: Tumor invades lamina propria, muscularis mucosae, or submucosa.  T2: Tumor invades muscularis propria. N0: No regional lymph node metastasis.  M0: No distant metastasis.  G1: Well differentiated.  G2: Moderately differentiated.  G3: Poorly differentiated.  GX: Grade cannot be assessed-stage grouping as G1. (AJCC 7th ed.)


name: Other Paralytic Syndrome following Non-Traumatic Intracerebral Hemorrhage Affecting Left Dominant Side

description: Evidence of other paralytic syndrome following non-traumatic intracerebral hemorrhage affecting left dominant side not specified elsewhere.


name: Acute Myocardial Injury without Ischemia, Heart Failure, Ventricular Dysfunction, or Myocarditis Related to COVID-19

description: Acute myocardial injury, without evidence of acute ischemia, heart failure, a newly reduced left or right ventricular ejection fraction, cardiogenic shock, or myocarditis in a patient with probable or confirmed acute COVID-19.


name: Colorectal Neuroendocrine Tumor cM0 TNM Finding v8

description: Colorectal neuroendocrine tumor without evidence of distant metastasis. (from AJCC 8th Ed.)


Grade 3 Alcohol Intolerance, CTCAE

description: Severe symptoms; limiting self care ADL


name: Carcinoma of the Conjunctiva pT4d TNM Finding v7

description: Carcinoma of the conjunctiva with tumor invading the brain. (from AJCC 7th Ed.)


Grade 3 Acidosis, CTCAE

description: pH <7.3


name: Kidney Cancer Pathologic Regional Lymph Nodes TNM Finding v6

description: A pathologic finding about one or more characteristics of kidney cancer, following the rules of the TNM AJCC v6 classification system as they pertain to staging of regional lymph nodes. Laterality does not affect the N classification.


name: Pathologic Stage IIIB Esophageal Adenocarcinoma AJCC v8

description: Stage IIIB includes: (T2, N2, M0, Any G); (T3, N1-2, M0, Any G); (T4a, N0-1, M0, Any G). T2: Tumor invades the muscularis propria. T3: Tumor invades adventitia. T4a: Tumor invades the pleura, pericardium, azygos vein, diaphragm, or peritoneum. N0: No regional lymph node metastasis. N1: Tumor with metastasis in one or two regional lymph nodes. N2: Tumor with metastasis in three to six regional lymph nodes. M0: No distant metastasis. (AJCC 8th ed.)


description: Evidence of cannabis abuse with intoxication with perceptual disturbance.


name: Acute exacerbation of chronic obstructive pulmonary disease

description: Evidence of chronic obstructive pulmonary disease with acute exacerbation.


Advanced gastric carcinoma

description: Gastric carcinoma that has metastasized from its original site of growth to distal anatomic sites or is no longer responding to treatment.


name: Other Specified Diabetes Mellitus with Proliferative Diabetic Retinopathy with Traction Retinal Detachment not Involving the Macula, Left Eye

description: Evidence of other specified diabetes mellitus with proliferative diabetic retinopathy with traction retinal detachment not involving the macula in the left eye not specified elsewhere.


Refractory Dedifferentiated Liposarcoma

description: Dedifferentiated liposarcoma that does not respond to treatment.


name: Unresectable Prostate Small Cell Neuroendocrine Carcinoma

description: Prostate small cell neuroendocrine carcinoma that is not amenable to surgical resection.


Flushing, CTCAE 5.0

description: A disorder characterized by episodic reddening of the skin, especially face, neck, or chest.


Cellulitis of pharynx

description: Cellulitis of the pharynx.


name: Grade 2 Scrotum Infection with Unknown Absolute Neutrophil Count, CTCAE


name: Grade 4 Blood Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


Lung Cancer pT2 TNM Finding v7

description: Lung cancer with a tumor size more than 3 cm but 7 cm or less or tumor with any of the following features (T2 tumors with these features are classified T2a if 5 cm or less): Involves main bronchus, 2 cm or more distal to the carina; Invades visceral pleura (PL1 or PL2); Associated with atelectasis or obstructive pneumonitis that extends to the hilar region but does not involve the entire lung.  (from AJCC 7th Ed.)


Fallopian Tube Cancer TNM Finding v7

description: A finding about one or more characteristics of fallopian tube cancer, following the rules of the TNM AJCC v7 classification system.  Histologic confirmation of primary disease with complete evaluation of the abdomen and pelvis is required. (from AJCC 7th Ed.)


name: High grade cervical glandular intraepithelial neoplasia

description: Cervical glandular intraepithelial neoplasia characterized by the presence of severe dysplastic changes.


name: Grade 3 Pharynx Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


name: Enteropathic Arthropathies, Unspecified Shoulder

description: Evidence of enteropathic arthropathies in an unspecified shoulder.


name: Carcinoma of the Lacrimal Gland Pathologic Distant Metastasis TNM Finding v7

description: A pathologic finding about one or more characteristics of carcinoma of the lacrimal gland, following the rules of the TNM AJCC v7 classification system as they pertain to distant metastases.  There is no pathologic M0 for carcinoma of the lacrimal gland. (from AJCC 7th Ed.)


Mucocutaneous candidiasis

description: A fungal infection of the skin, nails, oral and vaginal mucosal sites caused by species of the genus Candida. It manifests with white discoloration of the tongue and swelling, redness, and tenderness of the nails.


Severe Adverse Event

description: An adverse event experience that requires intensive therapeutic intervention and interrupts usual daily activities.


Extrahepatic bile duct cancer stage III

description: Stage III includes: T4, Any N, M0.  T4: Tumor invades any of the following main portal vein or its branches bilaterally, common hepatic artery, or other adjacent structures, such as the colon, stomach, duodenum, or abdominal wall.  N0: No regional lymph node metastasis.  N1: Regional lymph node metastasis.  M0: Distant metastasis. (AJCC 6th ed.)


name: Appendix Neuroendocrine Tumor pN1 TNM Finding v8

description: Appendix neuroendocrine tumor with regional lymph node metastasis. (from AJCC 8th Ed.)


Aplastic bone marrow

description: Depletion of stem cells in the bone marrow that results in the lack of production of hematopoietic cells.


name: Grade 2 Pleura Intra-Operative Injury, CTCAE


Cerebellar Paraganglioma

description: An extra-adrenal paraganglioma arising from the cerebellum.


name: Grade 4 Oral Intra-Operative Injury, CTCAE


name: Lymphoma by Lukes-Collins Classification (Antiquated)


name: Appendix Neuroendocrine Tumor pM1c TNM Finding v8

description: Appendix neuroendocrine tumor with both hepatic and extrahepatic metastases. (from AJCC 8th Ed.)


Testosterone Greater than 150 ng/dL

description: A semiquantitative finding indicating that the concentration of testosterone in a sample is greater than 150 ng/dL.


Glottic Cancer pMX TNM Finding v6

description: Glottic cancer in which distant metastasis cannot be assessed. (from AJCC 6th Ed.)


name: High Grade Prostatic Intraepithelial Neoplasia

description: Prostatic intraepithelial neoplasia characterized by the presence of morphologically malignant cells lining the acini and ducts.  The malignant cells are enlarged, contain prominent nucleoli, and have increased nuclear/cytoplasmic ratio.  The malignant cells may grow within the ducts and acini in four architectural patterns: flat, tufting, micropapillary, and cribriform.  The presence of high grade prostatic intraepithelial neoplasia in needle biopsy is a risk factor for the subsequent detection of carcinoma on repeat biopsy.


name: Grade 5 Intraoperative Renal Injury, CTCAE

description: Death


Grade 5 Pyramidal Tract Syndrome, CTCAE

description: Death


Cancer-related Symptom

description: A symptom that is associated with a cancer diagnosis or its treatment.


Grade 2 Feminization Acquired, CTCAE

description: Moderate symptoms; medical intervention indicated


Stage IV Ureter Cancer AJCC v7

description: Stage IV includes: (T4, N0, M0); (Any T, N1, M0); (Any T, N2, M0); (Any T, N3, M0); (Any T, Any N, M1).  T4: Tumor invades adjacent organs, or through the kidney into the perinephric fat.  N0: No regional lymph node metastasis.  N1: Metastasis in a single lymph node, 2 cm or less in greatest dimension.  N2: Metastasis in a single lymph node, more than 2 cm but not more than 5 cm in greatest dimension; or multiple lymph nodes, none more than 5 cm in greatest dimension.  N3: Metastasis in a lymph node, more than 5 cm in greatest dimension.  M0: No distant metastasis.  N1: Distant metastasis.  (AJCC 7th ed.)


name: Unspecified Juvenile Rheumatoid Arthritis, Left Shoulder

description: Evidence of unspecified juvenile rheumatoid arthritis in the left shoulder.


name: Thyroid Cancer Pathologic Distant Metastasis TNM Finding v7

description: A pathologic finding about one or more characteristics of thyroid cancer, following the rules of the TNM AJCC v7 classification system as they pertain to distant metastases.  There is no pathologic M0 for thyroid cancer.


Grade 2 Urinary Incontinence, CTCAE

description: Spontaneous; pads indicated; limiting instrumental ADL


Grade 5 Duodenal Hemorrhage, CTCAE

description: Death


name: Grade 4 Lung Infection with Unknown Absolute Neutrophil Count, CTCAE


name: Bipolar Disorder, Current Episode Manic without Psychotic Features, Mild

description: Evidence of bipolar disorder that is current episode manic without psychotic features that is mild.


name: Grade 5 Dental-Tooth Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


name: Urothelial (Transitional Cell) Carcinoma of the Prostate pTis pu TNM Finding v7

description: Urothelial (transitional cell) carcinoma of the prostate with a finding of carcinoma in situ and involvement of the prostatic urethra. (from AJCC 7th Ed.)


name: Grade 3 Pleura Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


name: Mixed Phenotype Acute Leukemia, B/T/Myeloid

description: A very rare mixed phenotype acute leukemia in which the blasts show evidence of B-cell, T-cell, and myeloid lineage but are negative for KMT2A rearrangement and t(9;22)(q34;q11.2) translocation.


Grade 3 Ileal Stenosis, CTCAE

description: Severely altered GI function; tube feeding or hospitalization indicated; elective operative intervention indicated


name: Bladder Urothelial Carcinoma, High Grade

description: Bladder urothelial carcinoma characterized by the presence of neoplastic epithelial cells with high grade features.


name: Appendiceal Carcinoma pM1 TNM Finding v7

description: Appendiceal carcinoma with distant metastasis. (from AJCC 7th Ed.)


Grade 3 Hypoxia, CTCAE

description: Decreased oxygen saturation at rest (e.g., pulse oximeter <88% or PaO2 <=55 mm Hg)


name: Appendiceal Carcinoma cM1 TNM Finding v8

description: Appendiceal carcinoma with distant metastasis. (from AJCC 8th Ed.)


name: Other Atherosclerosis of Other Type of Bypass Graft(s) of the Extremities, Bilateral Legs

description: Evidence of other atherosclerosis of other type of bypass graft(s) of the extremities in both legs not specified elsewhere.


Crude Oil Exposure

description: Environmental, occupational, or consumer-based exposure to volatiles derived from the organic compounds and polycyclic aromatic hydrocarbons and particulates that are present in crude oil.


name: Post transplant Epstein-Barr virus associated lymphoproliferative disorder

description: A lymphoproliferative disorder that develops following organ transplantation and is associated with Epstein-Barr virus infection.


name: Atherosclerosis of Unspecified Type of Bypass Graft(s) of the Extremities with Gangrene, Left Leg

description: Evidence of atherosclerosis of unspecified type of bypass graft(s) of the extremities with gangrene in the left leg.


name: Stage I Lentigo Maligna Melanoma AJCC v7

description: Stage I includes: IA: (T1a, N0, M0); IB: (T1b, N0, M0); (T2a, N0, M0).  T1a: Cutaneous melanoma with a tumor measuring 1.0 mm or less in thickness, without ulceration and mitosis less than 1/mm2.  T1b: Cutaneous melanoma with a tumor measuring 1.0 mm or less in thickness, with ulceration or mitoses equal to or more than 1/mm2. T2a: Cutaneous melanoma with a tumor measuring 1.01-2.0 mm in thickness, without ulceration.  N0: No regional lymph node metastases.  M0: No detectable evidence of distant metastases. (from AJCC 7th Ed.)


Cutaneous Melanoma pN2c TNM Finding v7

description: Cutaneous melanoma with intralymphatic metastases (in transit or satellite metastases) without metastatic nodes. (from AJCC 7th Ed.)


name: Urothelial (Transitional Cell) Carcinoma of the Prostate pTis pd TNM Finding v7

description: Urothelial (transitional cell) carcinoma of the prostate with a finding of carcinoma in situ and involvement of the prostatic ducts. (from AJCC 7th Ed.)


name: Grade 3 Prostate Infection with Unknown Absolute Neutrophil Count, CTCAE


name: Lacrimal Drainage System Mucoepidermoid Carcinoma

description: A carcinoma that arises from the lacrimal sac. It is characterized by the presence of squamous cells, mucus producing cells, and cells of intermediate type.


Paratesticular tumor

description: A benign, borderline, or malignant neoplasm that affects the paratesticular structures.


name: Grade 4 Upper Aerodigestive NOS Intra-Operative Injury, CTCAE


Grade 1 Pulmonary Hypertension, CTCAE

description: Minimal dyspnea; findings on physical exam or other evaluation


name: Pathologic Stage III Merkel Cell Carcinoma AJCC v8

description: Stage III includes: IIIA: (T1-4, N1a(sn) or N1a, M0); (T0, N1b, M0); IIIB: (T1-4, N1b-3, M0). T0: No evidence of primary tumor. T1: Maximum clinical tumor diameter equal to or less than 2 cm. T2: Maximum clinical tumor diameter more than 2 cm but equal to or less than 5 cm. T3: Maximum clinical tumor diameter more than 5 cm. T4: Primary tumor invades fascia, muscle, cartilage, or bone. N1a(sn): Clinically occult regional lymph node metastasis identified only by sentinel lymph node biopsy. N1a: Clinically occult regional lymph node metastasis following lymph node dissection. N1b: Clinically and/or radiologically detected regional lymph node metastasis, microscopically confirmed. N2: In-transit metastasis (discontinuous from primary tumor; located between primary tumor and draining regional nodal basin, or distal to the primary tumor) without lymph node metastasis. N3: In-transit metastasis (discontinuous from primary tumor; located between primary tumor and draining regional nodal basin, or distal to the primary tumor) with lymph node metastasis. M0: No distant metastasis detected on clinical and/or radiologic examination. (AJCC 8th ed.)


Felty's Syndrome, Left Shoulder

description: Evidence of Felty's syndrome in the left shoulder.


Prepubertal-Type Lesion

description: A lesion usually seen in prepubertal individuals. In cases of testicular germ cell tumors, it indicates that the tumors are not associated with chromosome 12p amplification or germ cell neoplasia in situ.


name: Colorectal Cancer Clinical TNM Finding v6


name: Duodenum/Ampulla/Jejunum/Ileum Neuroendocrine Tumor pM1 TNM Finding v7

description: Duodenum/ampulla/jejunum/ileum neuroendocrine tumor with distant metastasis. (from AJCC 7th Ed.)


Hypothalamic Gangliocytoma

description: A tumor characterized by the presence of mature ganglion cells and neuronal differentiation, arising in the hypothalamus. It is often associated with the presence of pituitary gland adenomas. Symptoms include acromegaly and precocious puberty.


Solicited Adverse Event

description: An adverse event that is reported by a healthcare professional, consumer, or patient through an organized data collection system.


name: Grade 5 Gastrointestinal Stoma Necrosis, CTCAE

description: Death


AIDS-Related Cervical Carcinoma

description: A carcinoma that arises from the cervix in a patient with acquired immunodeficiency syndrome.


name: CNS Necrosis and Cystic Progression, CTCAE


name: First-degree perineal laceration during delivery

description: Injury to perineal skin only. (reVITALize)


name: Juvenile Arthritis, Unspecified, Unspecified Wrist

description: Evidence of unspecified juvenile arthritis in the wrist.


Grade 4 Vaginal Fistula, CTCAE

description: Life-threatening consequences; urgent intervention indicated


P1 Hydronephrosis

description: Postnatal Hydronephrosis with the following clinical findings: 1) APRPD is 10 to less than 15 mm, 2) central calyceal dilation may be present, but peripheral calyceal dilation is considered to increase risk, 3) renal parenchyma should have normal thickness and appearance, 4) the ureter is not seen, and 5) the bladder is normal. If there is central calyceal dilation but the APRPD is less than 10 mm, it is still considered UTD P1. (Adapted from: Hiep T. Nguyen, Carol B. Benson, Bryann Bromley, Jeffrey B. Campbell, Jeanne Chow, Beverly Coleman, Christopher Cooper, Jude Crino, Kassa Darge, C.D. Anthony Herndon, Anthony O. Odibo, Michael J.G. Somers, Deborah R. Stein; Multidisciplinary consensus on the classification of prenatal and postnatal urinary tract dilation (UTD classification system); Pediatric Urology; December 2014 Volume 10, Issue 6, Pages 982-998)


Anosmia, CTCAE

description: A disorder characterized by a change in the sense of smell.


name: Exocrine Pancreatic Cancer pM1 TNM Finding v6

description: Exocrine pancreatic cancer with distant metastasis. (from AJCC 6th Ed.)


name: Hemoglobin Beta Heterozygous Null Genotype

description: A genetic finding indicating that one copy of chromosome 16 has a functional copy (B) of the hemoglobin beta gene (HBB) and the other copy has HBB loss of function or gene deletion mutations (B0). This genotype is associated with beta thalassemia minor.


Cheiromegaly

description: Abnormal enlargement of one or both hands, along with hyperhydrosis.


name: Grade 4 Prostate Stricture or Stenosis, CTCAE


name: Acute Myeloid Leukemia with t(4;11)(q21.3;q23.3); AFF1-KMT2A

description: An acute myeloid leukemia associated with t(4;11)(q21.3;q23.3) resulting in AFF1-KMT2A gene fusion.


name: Upper Aerodigestive Infection with Unknown Absolute Neutrophil Count NOS, CTCAE


name: Psoriatic arthritis with distal interphalangeal joint involvement

description: Psoriatic arthritis with a particular pattern of involvement that affects the joints closest to the nails in both fingers and toes.


name: Grade 1 Conjunctiva Intra-Operative Injury, CTCAE


name: Hereditary Transthyretin Amyloid Cardiomyopathy

description: Transthyretin amyloid cardiomyopathy caused by mutation(s) in the TTR gene, encoding transthyretin.


name: Grade 4 Pleura Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


name: Atherosclerosis of Other Type of Bypass Graft(s) of the Left Leg with Ulceration of Unspecified Site

description: Evidence of atherosclerosis of other type of bypass graft(s) of the left leg with ulceration of unspecified site.


Aerodigestive Invasive Malignancy

description: A finding indicating the presence of an invasive malignant neoplasm involving the respiratory tract and the upper digestive tract.


Grade 4 Bronchopulmonary Dysplasia, AE

description: An adverse event in a newborn characterized by the need for supplemental oxygen at 28 days AND need for greater than 30% oxygen AND positive pressure at 36 weeks postmenstrual age (PMA) in infants born less than 32 weeks' gestation; need for greater than 30% oxygen AND positive pressure by 56 days postnatal age in infants born greater than 32 weeks' gestation; need for greater than 30% oxygen AND positive pressure at discharge. Note: For conversion of oxygen administered by different modalities to fraction of inspired oxygen (FiO2): see http://nicutools.org/MediCalcs/ActualO2.php3.


name: Grade 1 Gastroesophageal Reflux Disease, CTCAE

description: Mild symptoms; intervention not indicated


name: Metastatic malignant neoplasm to left lung

description: Evidence of secondary malignant neoplasm of the left lung.


name: Other Stimulant Use, Unspecified with Stimulant-Induced Psychotic Disorder, Unspecified

description: Evidence of other stimulant use, unspecified with stimulant-induced psychotic disorder not specified elsewhere.


name: Merkel Cell Carcinoma cNX TNM Finding v8

description: Merkel cell carcinoma in which the regional lymph nodes cannot be clinically assessed (e.g., previously removed for another reason, or because of body habitus). (from AJCC 8th Ed.)


name: Sedative, Hypnotic or Anxiolytic Use, Unspecified with Sedative, Hypnotic or Anxiolytic-Induced Psychotic Disorder with Delusions

description: Evidence of sedative, hypnotic or anxiolytic use, unspecified with sedative, hypnotic or anxiolytic-induced psychotic disorder with delusions.


name: Gastric Neuroendocrine Tumor Pathologic Distant Metastasis TNM Finding v8

description: A pathologic finding about one or more characteristics of a gastric neuroendocrine tumor, following the rules of the TNM AJCC v8 classification system as they pertain to distant metastases.


name: Soft Tissue Sarcoma of the Head and Neck pT3 TNM Finding v8

description: Soft tissue sarcoma of the head and neck with tumor measuring more than 4 cm in greatest dimension. (from AJCC 8th Ed.)


name: Degeneration of nervous system due to alcohol

description: Evidence of degeneration of the nervous system due to alcohol.


Acute Myeloid Leukemia with BCOR-RARA

description: Acute myeloid leukemia with variant RARA rearrangement and expression of BCOR-RARA fusion protein.


Childhood Endocrine Neoplasm

description: A benign or malignant neoplasm arising from the epithelial cells of an endocrine organ during childhood.


Stage IA Pancreatic Cancer AJCC v8

description: Stage IA includes: T1, N0, M0. T1: Tumor measuring 2 cm or less in greatest dimension. N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 8th ed.)


Urostomy Site Bleeding, CTCAE

description: A disorder characterized by bleeding from the urostomy site.


name: Other Specified Malignant Neoplasm of Skin of Nose

description: Evidence of other specified malignant neoplasm of skin of nose not specified elsewhere.


name: Soft Tissue Sarcoma of the Retroperitoneum cM1 TNM Finding v8

description: Soft tissue sarcoma of the retroperitoneum with distant metastasis. (from AJCC 8th Ed.)


name: Subglottic Cancer pN0 TNM Finding v6 and v7

description: Subglottic cancer with no metastasis to regional lymph nodes. (from AJCC 6th and 7th Eds.)


name: Mycosis Fungoides and Sezary Syndrome N1 TNM Finding v7

description: Clinically abnormal peripheral lymph nodes; histopathology Dutch grade 1 or NCI LN0-2.  Note: Dutch grade 1: dermatopathic lymphadenopathy.  NCI LN0: no atypical lymphocytes.  NCI LN1: occasional and isolated atypical lymphocytes (not arranged in clusters).  NCI LN2: many atypical lymphocytes or in 3-6 cell clusters.  (from AJCC 7th Ed.)


name: Grade 2 Cranial Nerve X Neuropathy, CTCAE


name: Other Specified Diabetes Mellitus with Proliferative Diabetic Retinopathy with Traction Retinal Detachment Involving the Macula, Unspecified Eye

description: Evidence of other specified diabetes mellitus with proliferative diabetic retinopathy with traction retinal detachment involving the macula, unspecified eye not specified elsewhere.


name: Grade 1 Eye Disorders - Other, Specify, CTCAE

description: Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated; no change in vision


name: Small Intestine Cancer Pathologic TNM Finding v7

description: A pathologic finding about one or more characteristics of small intestine cancer, following the rules of the TNM AJCC v7 classification system.  The primary tumor is staged according to its depth of penetration and the involvement of adjacent structures or distant sites.  Lateral spread within the duodenum, jejunum, or ileum is not considered in this classification.  Only the depth of tumor penetration into the bowel wall and spread to other structures defines the pT stage.  (from AJCC 7th Ed.)


Hepatic Hemorrhage, CTCAE

description: A disorder characterized by bleeding from the liver.


name: Pleura Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


Grade 3 Necrotizing Enterocolitis, AE

description: An adverse event in a newborn characterized by confirmed necrotizing enterocolitis; major care change indicated (e.g. NPO, antibiotics, non-urgent surgery).


name: Childhood Acute Lymphoblastic Leukemia CNS-Positive Toronto Guidelines v2

description: Clinical signs of CNS involvement or blasts in CSF. (Childhood cancer staging for population registries according to the Toronto Childhood Cancer Stage Guidelines - Version 2. Cancer Council Queensland and Cancer Australia: Brisbane, Australia; 2021.)


name: Cutaneous Melanoma Pathologic Regional Lymph Nodes TNM Finding v7

description: A pathologic finding about one or more characteristics of cutaneous melanoma, following the rules of the TNM classification system as they pertain to staging of regional lymph nodes.  The TNM clinical and pathologic regional lymph nodes tumor classifications of cutaneous melanoma are not the same.  TNM pathologic findings are based on the pathologic examination of the regional lymph nodes after sentinel or complete lymphadenectomy. (from AJCC 7th Ed.)


name: Rheumatoid Myopathy with Rheumatoid Arthritis of Left Knee

description: Evidence of rheumatoid myopathy with rheumatoid arthritis of left knee.


name: Ampulla of Vater Cancer cM0 TNM Finding v8

description: Ampulla of Vater cancer without evidence of distant metastasis. (from AJCC 8th Ed.)


Substance Intoxication Delirium

description: A disorder characterized by the acute and sudden development of changes in attention, memory, language and/or perception that can be etiologically linked to the direct physiological consequences of substance intoxication.


name: Secondary pulmonary arterial hypertension

description: Evidence of secondary pulmonary arterial hypertension.


RASSF1 Gene Promoter Hypermethylation

description: A genetic finding indicating an excess of DNA methylation in the promoter region of the RASSF1 gene.


Lip Infection, CTCAE

description: A disorder characterized by an infectious process involving the lips.


name: Exocrine Pancreatic Cancer pT4 TNM Finding v6

description: Exocrine pancreatic cancer extending beyond the pancreas, involving the celiac axis or superior mesenteric artery and therefore unresectable. (from AJCC 6th Ed.)


Supraglottic Cancer pT4b TNM Finding v8

description: Supraglottic cancer with very advanced local disease. Tumor invades prevertebral space, encases carotid artery, or invades mediastinal structures. (from AJCC 8th Ed.)


Grade 5 Oral Hemorrhage, CTCAE

description: Death


name: Stage IIIA Uterine Corpus Cancer AJCC v7

description: Stage IIIA includes: T3a, N0, M0.  T3a: Tumor involves serosa and/or adnexa (direct extension or metastasis). N0: No regional lymph node metastasis. M0: No distant metastasis. This staging applies to carcinomas and carcinosarcomas. (AJCC 7th ed.)


name: Nasal Cavity and Ethmoid Sinus Cancer pT2 TNM Finding v6 and v7

description: Nasal cavity and ethmoid sinus cancer with tumor invading two subsites in a single region or extending to involve an adjacent region within the nasoethmoidal complex, with or without bony invasion. (from AJCC 6th and 7th Eds.)


Bone Age

description: An indication of skeletal growth potential based on skeletal maturity indicators, such as radiologic imaging of growth plates.


name: Ampulla of Vater Cancer Pathologic TNM Finding v8

description: A pathologic finding about one or more characteristics of ampulla of Vater cancer, following the rules of the TNM AJCC v8 classification system.


name: Grade 3 Cornea Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


Pericarditis, CTCAE

description: A disorder characterized by irritation to the layers of the pericardium (the protective sac around the heart).


Grade 1 Hemorrhoidal Hemorrhage, CTCAE

description: Mild symptoms; intervention not indicated


Grade 4 Hypokalemia, CTCAE

description: <2.5 mmol/L; life-threatening consequences


Grade 4 Lipase Increased, CTCAE

description: >5.0 x ULN and with signs or symptoms


name: Grade 3 Fallopian Tube Anastomotic Leak, CTCAE

description: Severe symptoms; invasive intervention indicated


name: Dementia in Other Diseases Classified Elsewhere with Behavioral Disturbance

description: Evidence of dementia in other diseases classified elsewhere with behavioral disturbance.


name: Progression or Relapse After Hematologic Improvement

description: Disease progression or the return of a disease after a period of remission, occurring after a hematologic improvement.


name: Cutaneous Hematopoietic and Lymphoid Cell Neoplasm

description: A neoplasm of hematopoietic and lymphoid cell origin that affects the skin.


name: Grade 2 Intraoperative Reproductive Tract Injury, CTCAE

description: Partial resection of injured organ/structure indicated


name: Adult Undifferentiated High Grade Pleomorphic Sarcoma of Bone

description: An undifferentiated high grade pleomorphic sarcoma that arises from the bone and occurs during adulthood.


name: Adrenal Cortical Carcinoma Pathologic Primary Tumor TNM Finding v8

description: A pathologic finding about one or more characteristics of adrenal cortical carcinoma, following the rules of the TNM AJCC v8 classification system as they pertain to staging of the primary tumor.


Early Stage Malignant Skin Neoplasm

description: A stage term that refers to a malignant tumor confined to a limited area of the skin without lymph node or distant metastases.


name: Other Specified Diabetes Mellitus with Other Diabetic Kidney Complication

description: Evidence of other specified diabetes mellitus with other diabetic kidney complication not specified elsewhere.


name: Nasopharyngeal Cancer pT4 TNM Finding v7

description: Nasopharyngeal cancer with intracranial extension and/or involvement of cranial nerves, hypopharynx, orbit, or with extension to the infratemporal fossa/masticator space. (from AJCC 7th Ed.)


name: Renal Pelvis and Ureter Cancer pNX TNM Finding v8

description: Renal pelvis and ureter cancer in which the regional lymph nodes cannot be assessed. (from AJCC 8th Ed.)


name: Acute Myeloid Leukemia with SRSF2 Mutation

description: An acute myeloid leukemia associated with SRSF2 gene mutation.


PSA Level Less than or Equal to 0.5

description: A blood concentration of prostate specific antigen less than or equal to 0.5 ng/mL.


Stage IV Vulvar Cancer AJCC v8

description: Stage IV includes: T1-T3, N3, M0-M1. T1: Tumor confined to the vulva and/or perineum. Multifocal lesions should be designated as such. The largest lesion or the lesion with the greatest depth of invasion will be the target lesion identified to address the highest pT stage. Depth of invasion is defined as the measurement of the tumor from the epithelial-stromal junction of the adjacent most superficial dermal papilla to the deepest point of invasion. T2: Tumor of any size with extension to adjacent perineal structures (lower/distal third of the urethra, lower/distal third of the vagina, anal involvement). T3: Tumor of any size with extension to any of the following: upper/proximal two-thirds of the urethra, upper/proximal two-thirds of the vagina, bladder mucosa, or rectal mucosa; or fixed to pelvic bone. N3: Fixed or ulcerated regional lymph node metastasis. M0: No distant metastasis. M1: Distant metastasis (including pelvic lymph node metastasis). (from AJCC 8th Ed.)


Grade 4 Papulopustular Rash, CTCAE

description: Life-threatening consequences


Testicular Cancer pN0 TNM Finding v8

description: Testicular cancer with no regional lymph node metastasis. (from AJCC 8th Ed.)


name: Adverse Event Associated with Growth and Development


Shingles, CTCAE

description: A disorder characterized by the reactivation of herpes zoster virus.


name: Lip and Oral Cavity Cancer TNM Finding v6

description: A finding about one or more characteristics of lip and oral cavity cancer, following the rules of the TNM AJCC v6 classification system.


name: Adverse Event Associated with the Nervous System


Locally Advanced Lymphoma

description: Lymphoma that has spread from its original site of growth to nearby tissues or lymph nodes.


name: Nontraumatic Intracerebral Hemorrhage, Multiple Localized

description: Evidence of nontraumatic intracerebral hemorrhage, multiple localized.


Opioid abuse, in remission

description: Evidence of opioid abuse, in remission.


name: Grade 4 Visceral Arterial Ischemia, CTCAE

description: Life-threatening consequences; evidence of end organ damage; urgent operative intervention indicated


name: High Grade Malignant Peripheral Nerve Sheath Tumor

description: A malignant peripheral nerve sheath tumor that is high-grade.


Cervical Cancer cT1 TNM Finding v8

description: Cervical carcinoma confined to uterus (extension to corpus should be disregarded). (from AJCC 8th Ed.)


name: Sedative, Hypnotic or Anxiolytic Dependence with Sedative, Hypnotic or Anxiolytic-Induced Psychotic Disorder, Unspecified

description: Evidence of sedative, hypnotic or anxiolytic dependence with sedative, hypnotic or anxiolytic-induced psychotic disorder.


Prostatic Hemorrhage, CTCAE

description: A disorder characterized by bleeding from the prostate gland.


name: Cranial Nerve IX Sensory Intra-Operative Injury, CTCAE


name: Breast Cancer Pathologic Distant Metastasis TNM Finding v6

description: A pathologic finding about one or more characteristics of breast cancer, following the rules of the TNM AJCC v6 classification system as they pertain to distant metastases. TNM pathologic distant metastasis findings are based on clinical findings supplemented by histopathologic examination of one or more tissue specimens acquired during surgery.


name: Juvenile Rheumatoid Arthritis with Systemic Onset, Right Elbow

description: Evidence of juvenile rheumatoid arthritis with systemic onset in the right elbow.


Clinical Partial Response

description: A decrease in the size and the extent of tissue involvement by cancer, based on physical exam, such as palpation.


Conditioned Insomnia

description: Insomnia that results from a developed tendency to not sleep well under particular conditions.


Broad Ligament Serous Cystadenoma

description: A rare serous cystadenoma arising from the broad ligament.


Lung consolidation

description: A chest X-ray finding indicating the presence of a radio-opaque area in the lung. The opacification is caused by fluid or solid material within the airways or lung parenchyma.


Grade 3 Aortic Valve Disease, CTCAE

description: Symptomatic; severe regurgitation or stenosis by imaging; symptoms controlled with medical intervention


Grade 3 Jejunal Ulcer, CTCAE

description: Severely altered GI function; TPN indicated; elective invasive intervention indicated


name: Refractory Non-Muscle Invasive Bladder Carcinoma

description: Non-muscle invasive bladder carcinoma that is resistant to treatment.


name: Melanoma in situ of skin structure of scalp and/or neck

description: Evidence of melanoma in situ of scalp and neck.


name: Malignant neoplasm, overlapping lesion of connective and soft tissue

description: Evidence of a malignant neoplasm of overlapping sites of the connective and soft tissue.


Childhood Dermal Nevus

description: A dermal nevus that occurs during childhood.


Vulvar Cancer Clinical TNM Finding v7

description: A clinical finding about one or more characteristics of vulvar cancer, following the rules of the TNM AJCC v7 classification system.


name: Adenocarcinoma in situ in villous adenoma

description: A non-invasive adenocarcinoma arising from a villous adenoma.


Childhood Gemistocytic Astrocytoma

description: A gemistocytic astrocytoma that occurs during childhood.


Streaking Artifact

description: An artifact resulting from an inconsistency in a single measurement.


Laryngeal Cancer pN3b TNM Finding v8

description: Laryngeal cancer with metastasis in a single ipsilateral lymph node, more than 3 cm in greatest dimension and ENE(+); or metastases in multiple ipsilateral, contralateral, or bilateral lymph nodes and any with ENE(+). (from AJCC 8th Ed.)


name: Grade 1 Trachea Intra-Operative Injury, CTCAE


Vaginal Mesonephric Adenocarcinoma

description: Vaginal adenocarcinoma that derives from Wolffian duct remnants and shows mesonephric differentiation.


name: FIGO Stage IIB Gestational Trophoblastic Tumor


name: Atherosclerosis of Non-Autologous Biological Bypass Graft(s) of Left Leg with Ulceration of Other Part of Lower Leg

description: Evidence of atherosclerosis of non-autologous biological bypass graft(s) of left leg with ulceration of other part of lower leg.


name: Tooth Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


Adult Acquired Toxoplasmosis

description: Toxoplasmosis acquired in adulthood.


High Grade Sarcoma

description: A sarcoma with the morphologic features of a high-grade tumor and lack of cellular differentiation.


name: Grade 4 Esophagus Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


name: Ovarian, Fallopian Tube, and Primary Peritoneal Carcinoma Pathologic Primary Tumor TNM Finding v8

description: A pathologic finding about one or more characteristics of ovarian, fallopian tube, or primary peritoneal carcinoma, following the rules of the TNM AJCC v8 classification system as they pertain to staging of the primary tumor. The definitions of the T categories correspond to the stages accepted by FIGO. (from AJCC 8th Ed.)


name: Cutaneous Follicular Center Lymphoma, Intra-abdominal Lymph Nodes

description: Evidence of cutaneous follicular center lymphoma in the intra-abdominal lymph nodes.


Conduction Disorder, CTCAE

description: A disorder characterized by pathological irregularities in the cardiac conduction system.


Malignant Neoplasm of Right Epididymis

description: Evidence of a malignant neoplasm of the right epididymis.


Grade 2 Pharyngeal Mucositis, CTCAE

description: Moderate pain, analgesics indicated; altered oral intake; limiting instrumental ADL


Grade 4 Extrapyramidal Disorder, CTCAE

description: Life-threatening consequences; urgent intervention indicated


name: Drug or Chemical Induced Diabetes Mellitus with Mild Non-Proliferative Diabetic Retinopathy with Macular Edema

description: Evidence of drug or chemical induced diabetes mellitus with mild non-proliferative diabetic retinopathy with macular edema.


name: Appendix Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


name: Grade 1 Uterus Stricture or Stenosis, CTCAE


name: Leiomyosarcoma and Endometrial Stromal Sarcoma Pathologic Distant Metastasis TNM Finding v7

description: A pathologic finding about one or more characteristics of leiomyosarcoma and endometrial stromal sarcoma, following the rules of the TNM AJCC v7 classification system as they pertain to distant metastases.  There is no pathologic M0.  (from AJCC 7th Ed.)


name: Lobular carcinoma in situ of left breast

description: Evidence of lobular carcinoma in situ of left breast.


name: Biliary Tree Right Hepatic Duct Intra-Operative Injury, CTCAE


Infusion Related Toxicity

description: Toxicity related to an infusion.


Locally Recurrent Malignant Neoplasm

description: The reemergence of a malignant neoplasm after a period of remission at the site of the original tumor or adjacent to it.


Grade 5 Abdominal Infection, CTCAE

description: Death


Cerebellar Glioblastoma

description: A glioblastoma that occurs in the cerebellum.


Grade 4 Sinus Disorder, CTCAE

description: Necrosis of soft tissue or bone; urgent operative intervention indicated


name: Acute Lymphoblastic Leukemia by ROSE Cluster

description: Unique gene expression-based patient cluster groups in high-risk B-precursor acute lymphoblastic leukemia determined by Recognition of Outliers by Sampling Ends (ROSE).


name: Cardiomyocyte-Specific Unmethylated CpG Pattern Positive

description: A finding indicating detection of a cardiomyocyte-specific pattern involving six unmethylated CpG islands within the RFLNA (FAM101A) gene locus. Detection of this pattern of unmethylated CpG islands in cell-free DNA (cfDNA) isolates is associated with cardiomyocyte death.


Bilateral Proliferative Retinopathy

description: Proliferative retinopathy occurring in both eyes.


name: Grade 2 Duodenum Stricture or Stenosis, CTCAE


name: atherosclerosis of other type of bypass graft of right leg with ulceration of other part of lower leg

description: Evidence of atherosclerosis of other type of bypass graft(s) of right leg with ulceration of other part of lower leg.


name: Intrahepatic Bile Duct Cancer Pathologic TNM Finding v8

description: A pathologic finding about one or more characteristics of intrahepatic bile duct cancer, following the rules of the TNM AJCC v8 classification system.


Stage IVB Bone Cancer AJCC v7

description: Stage IVB includes: (Any T, N1, Any M, Any G); (Any T, Any N, M1b, Any G).  N1: Regional lymph node metastasis.  M1b: Metastasis to other distant sites. (AJCC 7th ed.)


Microbial Identification Certainty

description: A qualification that describes the degree of certainty of the correctness of a microbial identification test result.


Molecular Major Response

description: A decrease in signs of cancer, supported by molecular analysis.


name: Grade 2 Biliary Tree Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


name: Grade 4 Ureter Stricture or Stenosis, CTCAE


name: Upper Gastrointestinal Tract Cancer TNM Finding v8

description: A finding about one or more characteristics of upper gastrointestinal tract cancer, following the rules of the TNM AJCC v8 classification system.


description: Evidence of alcohol abuse with alcohol-induced anxiety disorder.


name: Atherosclerosis of Unspecified Type of Bypass Graft(s) of the Extremities with Rest Pain, Unspecified Extremity

description: Evidence of atherosclerosis of unspecified type of bypass graft(s) of the extremities with rest pain in the unspecified extremity.


name: gestational diabetes mellitus in pregnancy, insulin controlled

description: Evidence of gestational diabetes mellitus in pregnancy that is insulin controlled.


Grade 4 Hypoparathyroidism, CTCAE

description: Life-threatening consequences; urgent intervention indicated


name: Cervix Intraepithelial Neoplasia Grade 3 AJCC v7

description: Stage 0 includes: (Tis, N0, M0). Tis: Carcinoma in situ. N0: No regional lymph node metastasis.  M0: No distant metastasis. FIGO no longer includes stage 0. (AJCC 7th ed.)


Hemoglobin Genotype Finding

description: A genetic finding indicating the genetic composition in a subject for the genes that encode hemoglobin subunits.


name: Other Specified Diabetes Mellitus with Moderate Nonproliferative Diabetic Retinopathy with Macular Edema, Left Eye

description: Evidence of other specified diabetes mellitus with moderate nonproliferative diabetic retinopathy with macular edema in the left eye not specified elsewhere.


Testicular Cancer cN2 TNM Finding v8

description: Testicular cancer with metastasis with a lymph node mass larger than 2 cm but not larger than 5 cm in greatest dimension or multiple lymph nodes, any one mass larger than 2 cm but not larger than 5 cm in greatest dimension. (from AJCC 8th Ed.)


name: Umbilical hernia without mention of obstruction or gangrene

description: The protrusion of contents of the abdominal cavity through the abdominal wall, at the site of the umbilicus, without mention of obstruction or necrosis of the herniated contents.


name: Grade 2 Heart Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


name: Major Salivary Gland Cancer pN2c TNM Finding v6 and v7

description: Major salivary gland cancer with metastasis in bilateral or contralateral lymph nodes, none more than 6 cm in greatest dimension. (from AJCC 6th and 7th Eds.)


name: Dissection of Other Precerebral Arteries

description: Evidence of dissection of other precerebral arteries.


name: Locally Advanced Cervical Adenocarcinoma

description: A cervical adenocarcinoma that has spread from its original site of growth to nearby tissues or lymph nodes.


Non-small cell carcinoma

description: A malignant epithelial neoplasm characterized by the absence of neoplastic small epithelial cells. A representative example is the lung non-small cell carcinoma.


Tumors Derived from Langerhans Cells

description: This category includes two main sub-groups, according to the degree of cytological atypia and clinical aggressiveness: Langerhans cell histiocytosis and Langerhans cell sarcoma. (WHO 2017)


Racial Melanosis

description: A benign conjunctival finding noted especially among darker pigmented individuals. While it is typically found perilimbally and bilaterally, it can also cover the conjunctivae extensively and may present asymmetrically. The flat, non-cystic pigmentation may increase in size with age. It is rare to have this finding evolve into conjunctival melanoma.


Grade 5 Tracheal Obstruction, CTCAE

description: Death


Broad Ligament Wolffian Tumor

description: An epithelial neoplasm of Wolffian (mesonephric) origin arising from the broad ligament. Most tumors behave in a benign fashion.


Grade 1 Tendon Reflex Decreased, CTCAE

description: Ankle reflex reduced


name: Lip and Oral Cavity Cancer Pathologic TNM Finding v8

description: A pathologic finding about one or more characteristics of lip and oral cavity cancer, following the rules of the TNM AJCC v8 classification system.  The pathologic staging is determined after the complete resection of the primary site and/or regional nodal dissection, followed by pathologic examination of the resected specimen(s).  (from AJCC 8th Ed.)


name: Grade 3 Central Nervous System Hemorrhage, CTCAE


name: Grade 4 Genitourinary Stoma Obstruction, CTCAE


name: Atherosclerosis of Autologous Vein Bypass Graft(s) of Right Leg with Ulceration of Heel and Midfoot

description: Evidence of atherosclerosis of autologous vein bypass graft(s) of right leg with ulceration of heel and midfoot.


name: Pathologic Stage IIID Cutaneous Melanoma AJCC v8

description: Stage IIID includes: T4b, N3a/b/c, M0. T4b: Tumor measuring more than 4.0 mm in thickness. Ulceration status: With ulceration.  N3a: Four or more clinically occult nodal metastasis (i.e., detected by sentinel lymph node biopsy). Presence of in-transit, satellite, and/or microsatellite metastases: No. N3b: Four or more nodal metastases, at least one of which was clinically detected, or presence of any number of matted nodes. Presence of in-transit, satellite, and/or microsatellite metastases: No. N3c: Two or more clinically occult nodal metastases. Presence of in-transit, satellite, and/or microsatellite metastases: Yes. M0: No evidence of distant metastasis. LDH level is not applicable. (AJCC 8th ed.)


ARID1A Negative

description: An indication that ARID1A expression has not been detected in a sample.


SPN Negative

description: An indication that SPN expression has not been detected in a sample.


name: Grade 3 Intraoperative Neurological Injury, CTCAE

description: Complete resection or reconstruction of injured organ/structure indicated; limiting self care ADL


name: Mycosis Fungoides and Sezary Syndrome N2 TNM Finding v7

description: Clinically abnormal peripheral lymph nodes; histopathology Dutch grade 2 or NCI LN3.  Note: Dutch grade 2: dermatopathic lymphadenopathy; early involvement by mycosis fungoides (presence of cerebriform nuclei greater than 7.5 micrometers).  NCI LN3: aggregates of atypical lymphocytes; nodal architecture preserved.  (from AJCC 7th Ed.)


name: Grade 1 Duodenum Stricture or Stenosis, CTCAE


name: Atherosclerosis of Non-Biological Bypass Graft(s) of the Extremities with Rest Pain, Unspecified Extremity

description: Evidence of atherosclerosis of non-biological bypass graft(s) of the extremities with rest pain, unspecified extremity.


name: Recurrent Acute Promyelocytic Leukemia with t(15;17)(q24.1;q21.2); PML-RARA

description: The reemergence of acute promyelocytic leukemia with t(15;17)(q24.1;q21.2); PML-RARA after a period of remission.


name: Mediastinal Germ Cell Tumor T2a TNM Finding

description: Mediastinal germ cell tumor infiltrating contiguous organs or accompanied by malignant effusion and measuring 5 cm or less. (WHO Classification of Tumors of the Lung, Pleura, Thymus and Heart, 2015)


Urinary complication

description: Any disorder of the organs of the urinary system occurring as a consequence of injury to the urinary system.


Chest Pain - Cardiac, CTCAE

description: A disorder characterized by substernal discomfort due to insufficient myocardial oxygenation e.g., angina pectoris.


name: Grade 3 Urethra Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


Grade 4 Atelectasis, CTCAE

description: Life-threatening respiratory or hemodynamic compromise; intubation or urgent intervention indicated


Grade 2 Agitation, CTCAE

description: Moderate mood alteration


name: Stage M3 Childhood Ependymoma by Toronto Guidelines v2

description: Visible metastasis in spine or visible metastasis in cervicomedullary junction. (Childhood cancer staging for population registries according to the Toronto Childhood Cancer Stage Guidelines - Version 2. Cancer Council Queensland and Cancer Australia: Brisbane, Australia; 2021.)


name: Duodenum/Ampulla/Jejunum/Ileum Neuroendocrine Tumor Clinical Distant Metastasis TNM Finding v7

description: A clinical finding about one or more characteristics of duodenum/ampulla/jejunum/ileum neuroendocrine tumor, following the rules of the TNM AJCC v7 classification system as they pertain to distant metastases.


name: Malignant neoplasm of connective and soft tissue of head, face and neck

description: Evidence of a malignant neoplasm of connective and soft tissue of head, face and neck.


Colorectal Cancer pN1 TNM Finding v6

description: Colorectal cancer with metastasis in 1-3 regional lymph nodes. (from AJCC 6th Ed.)


Midgut Neuroendocrine Tumor

description: A neuroendocrine tumor that arises from the jejunum, ileum, proximal colon, or appendix.


name: Grade 1 Muscular and Skeletal Hypoplasia, CTCAE


name: Grade 3 Retroperitoneum Hemorrhage, CTCAE


name: Idiopathic Dysplasia of Uncertain Significance

description: Prominent hematopoietic cell dysplasia with mild or absent cytopenia. It may progress to an overt myelodysplastic syndrome or other myeloid neoplasms such as acute myeloid leukemia, myeloproliferative neoplasm, or mast cell disorder.


name: Increased Uptake by 123-Iodine-Meta-Iodobenzylguanidine Scintigraphy


name: Malignant Neoplasm of Lower-Outer Quadrant of Left Male Breast

description: Evidence of a malignant neoplasm of the lower-outer quadrant of left male breast.


name: Schizophrenia and other psychotic disorders

description: A category of psychiatric disorders characterized by the presence of psychotic symptoms such as delusions or hallucinations or negative symptoms such as affective flattening.


name: Other Specified Diabetes Mellitus with Diabetic Amyotrophy

description: Evidence of other specified diabetes mellitus with diabetic amyotrophy not specified elsewhere.


Immunoresponse

description: A marked decrease in contrast enhancement that is not due to actual tumor shrinkage, but that may be due to immunotherapy.


Tubal Hyperplasia

description: Benign proliferation of the fallopian tube epithelium.


Abdominal Bruit Present

description: An indication that auscultation of the major arteries of the abdomen demonstrates the presence of turbulent vascular sounds.


Liver Cancer Pathologic TNM Finding v6

description: A pathologic finding about one or more characteristics of liver cancer, following the rules of the TNM AJCC v6 classification system. TNM pathologic findings are based on clinical findings supplemented by histopathologic examination of one or more tissue specimens acquired during surgery.


name: Unspecified Atherosclerosis of Non-Autologous Biological Bypass Graft(s) of the Extremities, Left Leg

description: Evidence of unspecified atherosclerosis of non-autologous biological bypass graft(s) of the extremities in the left leg.


Grade 3 Concentration Impairment, CTCAE

description: Severe impairment in attention or decreased level of concentration; limiting self care ADL


name: Appendix Neuroendocrine Tumor pT0 TNM Finding v8

description: Appendix neuroendocrine tumor with no evidence of primary tumor. (from AJCC 8th Ed.)


name: Mediastinal Germ Cell Tumor T2 TNM Finding

description: Mediastinal germ cell tumor infiltrating contiguous organs or accompanied by malignant effusion. (WHO Classification of Tumors of the Lung, Pleura, Thymus and Heart, 2015)


name: acute combined systolic and diastolic congestive heart failure

description: Acute congestive heart failure due to reduced contractility of the left ventricle and which does not fill properly due to decreased compliance.


Occupational Generator Smoke Exposure

description: Occupational exposure to airborne gases and particulates during the operation of a power generator.


Atrioventricular Block Complete, CTCAE

description: A disorder characterized by a dysrhythmia with complete failure of atrial electrical impulse conduction through the AV node to the ventricles.


MET/CEP7 Copy Number Ratio Finding

description: A genetic copy number finding indicating the ratio of the number of signals for a probe targeting the MET gene to the number of signals for a probe targeting the centromere of chromosome 7 (CEP7).


Hepatocellular Carcinoma TNM Finding v8

description: A finding about one or more characteristics of hepatocellular carcinoma, following the rules of the TNM AJCC v8 classification system. This staging system applies to hepatocellular carcinomas and fibrolamellar carcinomas (fibrolamellar variant of hepatocellular carcinoma). Intrahepatic cholangiocarcinomas, combined hepatocellular-cholangiocarcinomas, and sarcomas of the liver are not staged using this staging system. (from AJCC 8th Ed.)


Abnormal Finding

description: A decision that an observation or result is outside the parameters considered normal.


name: Cerebral Infarction due to Thrombosis Unspecified Vertebral Artery

description: Evidence of cerebral infarction due to a thrombosis of an unspecified vertebral artery.


Trichilemmal carcinoma

description: A rare malignant tumor arising from the outer hair sheath and infundibulum on the face. It is considered the malignant counterpart of tricholemmoma. Complete surgical excision is required.


name: Grade 3 Pregnancy, Puerperium and Perinatal Conditions - Other, Specify, CTCAE

description: Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL


name: PSA Level Less than or Equal to One Hundred

description: A blood concentration of prostate specific antigen less than or equal to 100 ng/mL.


Stage IIIB Vulvar Cancer AJCC v7

description: Stage IIIB includes: (T1/T2, N2a/N2b, M0).  T1: Invasive vulvar cancer confined to the vulva or perineum.  T2: Vulvar cancer with tumor of any size with extension to adjacent perineal structures (lower/distal 1/3 urethra, lower/distal 1/3 vagina, anal involvement).  N2a: Vulvar cancer with three or more lymph node metastases each measuring 5 mm or less.  N2b: Vulvar cancer with two or more lymph node metastases measuring 5 mm or greater.  M0: No distant metastasis.  (AJCC 7th ed.)


name: Major Salivary Gland Cancer pM1 TNM Finding v8

description: Major salivary gland cancer with distant metastasis. (from AJCC 8th Ed.)


name: Localization-Related Symptomatic Epilepsy and Epileptic Syndromes with Complex Partial Seizures, Intractable, with Status Epilepticus

description: Evidence of localization-related symptomatic epilepsy and epileptic syndromes with complex partial seizures, with status epilepticus that does not respond optimally to treatment.


PSA Level Twenty to One Hundred Fifty

description: A blood concentration of prostate specific antigen between 20 ng/mL and 150 ng/mL.


name: Dermatopolymyositis, Unspecified with Other Organ Involvement

description: Evidence of dermatopolymyositis, unspecified with other organ involvement.


name: Other Specified Rheumatoid Arthritis, Left Shoulder

description: Evidence of other specified rheumatoid arthritis in the left shoulder not specified elsewhere.


name: Gestational Trophoblastic Neoplasm pT0 TNM Finding v8

description: Gestational trophoblastic neoplasm with no evidence of primary tumor. (from AJCC 8th Ed.)


name: Ovarian, Fallopian Tube, and Primary Peritoneal Carcinoma cM1b TNM Finding v8

description: Ovarian, fallopian tube, or primary peritoneal carcinoma with liver or splenic parenchymal metastases; metastases to extra-abdominal organs (including inguinal lymph nodes and lymph nodes outside the abdominal cavity); transmural involvement of intestine. (from AJCC 8th Ed.)


name: Post-Procedural Heart Failure following Cardiac Surgery

description: Evidence of post-procedural heart failure following cardiac surgery.


name: Grade 3 Carbon Monoxide Diffusing Capacity Decreased, CTCAE

description: Asymptomatic decrease of >8 units drop; >5 units drop along with the presence of pulmonary symptoms (e.g., >Grade 2 hypoxia or >Grade 2 dyspnea); intervention indicated


name: Nasopharyngeal Cancer pN3 TNM Finding v7

description: Nasopharyngeal cancer with metastasis in a lymph node (s) more than 6 cm in greatest dimension and/or to supraclavicular fossa.  Supraclavicular zone or fossa is relevant to the staging of nasopharyngeal carcinoma and is the triangular region originally described by Ho.  It is defined by three points: (1) the superior margin of the sternal end of the clavicle, (2) the superior margin of the lateral end of the clavicle, (3) the point where the neck meets the shoulder.  This would include caudal portions of levels IV and VB.  All cases with lymph nodes (whole or part) in the fossa are considered N3b. (from AJCC 7th Ed.)


name: Low Grade Gastric Intraepithelial Neoplasia

description: A gastric intraepithelial lesion characterized by the presence of neoplastic cells with mild cytologic atypia, mild architectural changes, and low number of mitotic figures.


Laryngeal Hemorrhage, CTCAE

description: A disorder characterized by bleeding from the larynx.


name: Atherosclerosis of Native Arteries of Extremities with Rest Pain, Left Leg

description: Evidence of atherosclerosis of native arteries of extremities with rest pain in the left leg.


name: Anaplastic Large Cell Lymphoma, Lymphomatoid Papulosis-Like Histology

description: An anaplastic large cell lymphoma characterized by the presence of histopathologic features reminiscent of lymphomatoid papulosis. These features include the presence of Hodgkin-like cells in a background of acute and chronic inflammation.


Electrolyte Absorption Alteration

description: A finding indicating a deficiency or excess in biological absorption or assimilation of one or more electrolytes.


name: Other specified extrapyramidal and movement disorders

description: Evidence of other specified extrapyramidal and movement disorders not specified elsewhere.


Grade 3 Ascites, CTCAE

description: Severe symptoms; invasive intervention indicated


Sinus Tachycardia, CTCAE 5.0

description: A disorder characterized by a dysrhythmia with a heart rate greater than 100 beats per minute that originates in the sinus node.


Partial thickness burn

description: An injury that includes the entire epidermis and upper layers of the dermis due to a chemical, friction, radiation or thermal exposure. The affected area appears as moist red or white skin that does not blanch. Often it is painful with the presence of blisters.


name: Exocrine Pancreatic Cancer pT1 TNM Finding v6

description: Exocrine pancreatic cancer with tumor confined to the pancreas and 2 cm or less in greatest dimension. (from AJCC 6th Ed.)


name: Hodgkin's disease, lymphocytic depletion of lymph nodes of multiple sites

description: Ann Arbor Classification: Stage III: Involvement of lymph node regions on both sides of the diaphragm (III), which also may be accompanied by extralymphatic extension in association with adjacent lymph node involvement (IIIE) or by involvement of the spleen (IIIS) or both (IIIE,S).


name: PSA Decline Greater than or Equal to 25 Percent

description: A finding indicating that the blood concentration of prostate specific antigen in a subject's sample has decreased by at least 25 percent from the concentration recorded for a previous sample from that subject.


name: Adenocarcinoma of the prostate stage III

description: Stage III includes: T3a-b, N0, M0, Any PSA, Any Gleason.  cT3a: Tumor with extracapsular extension (unilateral or bilateral).  pT3a: Tumor with extraprostatic extension or microscopic invasion of bladder neck.  T3b: Tumor invades seminal vesicle(s).  cN0: No regional lymph node metastasis.  pN0: No positive regional nodes.  M0: No distant metastasis.  (AJCC 7th ed.)


name: Neonatal Intraventricular Hemorrhage, AE

description: An adverse event in a newborn characterized by bleeding into the lateral cerebral ventricles.


name: Grade 3 Peritoneal Cavity Intra-Operative Injury, CTCAE


Grade 1 Pleuritic Pain, CTCAE

description: Mild pain


name: Conjunctival Carcinoma pTis TNM Finding v8

description: Conjunctival carcinoma with a finding of carcinoma in situ. (from AJCC 8th Ed.)


name: Rheumatoid Arthritis without Rheumatoid Factor, Left Ankle and Foot

description: Evidence of rheumatoid arthritis without rheumatoid factor in the left ankle and foot.


Erosion lesion

description: An eating away or breakdown of any type of external or internal human tissue including but not limited to skin, teeth, mucosa, or somatic, which involves only the outer tissue layer. When tissue surrounds an implanted device, the tissue breakdown may result in migration and loss of the implant material and may result in further complications such as infection or abscess.


name: Cutaneous Melanoma cM1d(1) TNM Finding v8

description: Cutaneous melanoma with distant metastasis to CNS with or without M1a, M1b, or M1c sites of disease.  LDH level elevated. (from AJCC 8th Ed.)


Grade 1 Myelitis, CTCAE

description: Asymptomatic; mild signs (e.g., Babinski's reflex or Lhermitte's sign)


Cyanotic Attacks in Children

description: Episodes of cyanosis that result from breath holding spells in response to anger or frustration, during childhood. These episodes usually resolve in a few seconds.


Unresectable Ampulla of Vater Carcinoma

description: Carcinoma that arises from the ampulla of Vater and is not amenable to surgical resection.


name: Grade 3 Pancreas Infection with Unknown Absolute Neutrophil Count, CTCAE


name: Testicular Cancer Pathologic Primary Tumor TNM Finding v7

description: A pathologic finding about one or more characteristics of testicular cancer, following the rules of the TNM AJCC v7 classification system as they pertain to staging of the primary tumor.  The extent of primary tumor is usually classified after radical orchiectomy, and for this reason, a pathologic stage is assigned.  (from AJCC 7th Ed.)


name: Grade 4 Heart Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


Grade 3 Biliary Tract Infection, CTCAE

description: IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated


name: Grade 5 Larynx Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


name: Small Intestine Cancer Clinical TNM Finding v8

description: A clinical finding about one or more characteristics of small intestine cancer, following the rules of the TNM AJCC v8 classification system.


Fistula of the female genital organs

description: An abnormal communication between a female reproductive system organ and another organ or cavity.


Lung Cancer pN0 TNM Finding v8

description: Lung cancer without regional lymph node metastasis. (from AJCC 8th Ed.)


Occupational Foundry Smoke Exposure

description: Occupational exposure to airborne gases and particulates during the operation of a foundry.


Carcinoma Metastatic to the Skin

description: A carcinoma that has spread to the skin from its original site of gowth.


name: Intravesical Bacillus Calmette-Guerin Therapy Failure

description: Failure to achieve a disease-free state following BCG treatment.


name: Other Paralytic Syndrome following Non-Traumatic Subarachnoid Hemorrhage Affecting Left Non-Dominant Side

description: Evidence of other paralytic syndrome following non-traumatic subarachnoid hemorrhage affecting left non-dominant side not specified elsewhere.


name: Atherosclerosis of Autologous Vein Bypass Graft(s) of Left Leg with Ulceration of Unspecified Site

description: Evidence of atherosclerosis of autologous vein bypass graft(s) of left leg with ulceration of unspecified site.


Testicular Non-Neoplastic Disorder

description: A non-neoplastic disorder that affects the testis.  Representative examples include infection, torsion, and infarction.


name: Grade 3 Injury To Inferior Vena Cava, CTCAE

description: Severe symptoms; limiting self care ADL; repair or revision indicated


name: Other Specified Diabetes Mellitus with Mild Nonproliferative Diabetic Retinopathy without Macular Edema, Bilateral

description: Evidence of other specified diabetes mellitus with mild nonproliferative diabetic retinopathy without macular edema that is bilateral not specified elsewhere.


name: Endocrine Disorders - Other, Specify, CTCAE


PSA Level Greater than Fifteen

description: A blood concentration of prostate specific antigen greater than 15 ng/mL.


Mucosal Infection, CTCAE

description: A disorder characterized by an infectious process involving a mucosal surface.


name: Appendiceal Carcinoma pNX TNM Finding v8

description: Appendiceal carcinoma in which the regional lymph node(s) cannot be assessed.  (from AJCC 8th Ed.)


Grade 3 Hematoma, CTCAE

description: Transfusion; invasive intervention indicated


name: Primary Mediastinal (Thymic) Large B-Cell Lymphoma, Lymph Nodes of Multiple Sites

description: Evidence of primary mediastinal (thymic) large B-cell lymphoma in the lymph nodes of multiple sites.


Abnormal Blood Prolactin

description: A laboratory test result which indicates abnormal levels of prolactin hormone in the blood.


name: Advanced Digestive System Neuroendocrine Tumor G1

description: Digestive system neuroendocrine tumor G1 that has spread extensively to other anatomic sites or is no longer responding to treatment.


Refractory Metastatic Melanoma

description: Metastatic melanoma that is resistant to treatment.


Breast Cancer pT4a TNM Finding v8

description: Breast cancer with extension to the chest wall; invasion or adherence to pectoralis muscle in the absence of invasion of chest wall structures does not qualify as T4. (from AJCC 8th Ed.)


Stage IV Bone Sarcoma AJCC v7

description: Stage IV includes: IVA (Any T, N0, M1a, Any G); IVB (Any T, N1, Any M, Any G); (Any T, Any N, M1b, Any G).  N0: No regional lymph node metastasis.  N1: Regional lymph node metastasis.  M1a: Distant metastasis to lung.  M1b: Metastasis to other distant sites. (AJCC 7th ed.)


name: Grade 5 Fallopian Tube Obstruction, CTCAE


Pancreatic Hepatoid Adenocarcinoma

description: A rare adenocarcinoma that arises from the pancreas.  It is characterized by marked hepatocellular differentiation.


Stage I Ampulla of Vater Cancer AJCC v8

description: Stage I includes: IA: (T1a, N0, M0); IB: (T1b, N0, M0); (T2, N0, M0). T1a: Tumor limited to ampulla of Vater or sphincter of Oddi. T1b: Tumor invading beyond the sphincter of Oddi (perisphincteric invasion) and/or into the duodenal submucosa. T2: Tumor invading into the muscularis propria of the duodenum. N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 8th ed.)


name: Grade 1 Other Dermatology or Skin, CTCAE


name: Acute Myeloid Leukemia with idic(X)(q13)

description: Acute myeloid leukemia associated with isodicentric chromosome Xq13 [idic(X)(q13)].


name: Apraxia following Unspecified Cerebrovascular Disease

description: Evidence of apraxia following unspecified cerebrovascular disease.


name: Grade 3 Cecum Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


Kidney Pain, CTCAE

description: Kidney pain that is temporally associated with the use of a medical treatment or procedure, and that may or may not be considered related to the medical treatment or procedure.


name: Maxillary Sinus Cancer pT2 TNM Finding v8

description: Maxillary sinus cancer with tumor causing bone erosion or destruction including extension into the hard palate and/or middle nasal meatus, except extension to posterior wall of maxillary sinus and pterygoid plates. (from AJCC 8th Ed.)


name: Grade 4 Urethral Anastomotic Leak, CTCAE

description: Life-threatening consequences; urgent operative intervention indicated


name: Insulin-dependent diabetes mellitus with unspecified complications

description: Evidence of type 1 diabetes mellitus with unspecified complication.


name: Non-Muscle Invasive Bladder Urothelial Carcinoma

description: An infiltrating urothelial carcinoma of the bladder that has not invaded into the bladder muscularis propria.


name: Cranial Nerve VIII Intra-Operative Injury, CTCAE


PSA Doubling Time Greater than 6 Months

description: An indication that it took more than six months for a subject's blood concentration of prostate specific antigen to double.


name: Grade 1 Prolapse of Intestinal Stoma, CTCAE

description: Asymptomatic; reducible


name: Grade 5 Surgical and Medical Procedures - Other, Specify, CTCAE

description: Death


name: Follicular Lymphoma Grade IIIa, Lymph Nodes of Multiple Sites

description: Evidence of follicular lymphoma grade IIIa in the lymph nodes of multiple sites.


name: Cerebral Infarction due to Embolism of Unspecified Vertebral Artery

description: Evidence of cerebral infarction due to an embolism of an unspecified vertebral artery.


name: Cerebral Infarction due to Thrombosis of Bilateral Middle Cerebral Arteries

description: Evidence of cerebral infarction due to a thrombosis of the bilateral middle cerebral arteries.


Grade 1 Gallbladder Obstruction, CTCAE

description: Asymptomatic; clinical or diagnostic observations only; intervention not indicated


Bradyphagia

description: Abnormally slow eating.


Non-Invasive Cribriform Carcinoma

description: A carcinoma characterized by the presence of a cribriform architectural pattern. There is no evidence of surrounding stromal invasion by the malignant cells.


GNAQ Gene Mutation Negative

description: A genetic finding indicating that GNAQ gene mutations have not been detected in a sample.


name: Chronic Myelomonocytic Leukemia with Eosinophilia Associated with t(5;12)(q31;p12)

description: Chronic myelomonocytic leukemia characterized by the presence of eosinophilia, PDGFRB gene rearrangement, and t(5;12)(q31;p12).


Torsade de Pointes, CTCAE

description: A type of polymorphic ventricular tachycardia (VT) characterized by a gradual change in the amplitude and twisting of the QRS complexes around the isoelectric line.


Grade 1 Platelet Count Decreased, CTCAE

description: <LLN-75,000/mm3; <LLN-75.0 x 10e9/L


name: Secondary malignant neoplasm of other specified sites

description: Evidence of secondary malignant neoplasm of other specified sites.


name: Stage IVB Oral Cavity Verrucous Carcinoma


Creatinine Level Finding

description: A finding that indicates the amount of creatinine in a sample.


Stage IVA Gallbladder Cancer AJCC v8

description: Stage IVA includes: T4, N0-1, M0. T4: Tumor invading the main portal vein or hepatic artery or invading two or more extrahepatic organs or structures. N0: No regional lymph node metastasis. N1: Metastases to one to three regional lymph nodes. M0: No distant metastasis. (AJCC 8th ed.)


name: Grade 2 Jejunum Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


name: Grade 3 Respiratory, Thoracic and Mediastinal Disorders - Other, Specify, CTCAE

description: Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL


Propane Smoke Exposue

description: Environmental, occupational or consumer-based exposure to airborne gases and particulates produced when propane is rapidly oxidized via combustion.


name: Unspecified Viral Hepatitis B with Hepatic Coma

description: Evidence of unspecified viral hepatitis B with hepatic coma.


name: Grade 3 Aspartate Aminotransferase Increased, CTCAE

description: >5.0-20.0 x ULN if baseline was normal; >5.0-20.0 x baseline if baseline was abnormal


name: Grade 4 Meninges Infection with Unknown Absolute Neutrophil Count, CTCAE


name: Urinary Tract Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils NOS, CTCAE


name: Mitochondrial Uncoupling Protein 2 Hyperinsulinism

description: Hyperinsulinism due to mutation(s) in the gene UCP2, encoding mitochondrial uncoupling protein 2, which plays a role in attenuating insulin secretion.


name: Colorectal Cancer pT1 TNM Finding v6 and v7

description: Colorectal cancer with invasion into the submucosa. (from AJCC 6th and 7th Eds.)


Supratentorial Ependymoma

description: A circumscribed ependymoma that arises from the supratentorial region of the brain. The diagnosis of supratentorial ependymoma should be made either when genetic analysis did not reveal a fusion gene involving ZFTA or YAP1 genes (not elsewhere classified -NEC) or when the genetic analysis was unsuccessful or not reported (not otherwise specified-NOS).


name: Hypopharyngeal Cancer Pathologic Primary Tumor TNM Finding v6

description: A pathologic finding about one or more characteristics of hypopharyngeal cancer, following the rules of the TNM AJCC v6 classification system as they pertain to staging of the primary tumor.


Pediatric Disorder

description: A non-neoplastic or neoplastic disorder which occurs during infancy, childhood, or adolescence.


name: Unspecified Asthma with Status Asthmaticus

description: Evidence of unspecified asthma with status asthmaticus.


name: Uterine Corpus Carcinoma Clinical Distant Metastasis TNM Finding v7

description: A clinical finding about one or more characteristics of uterine corpus carcinoma, following the rules of the TNM AJCC v7 classification system as they pertain to distant metastases. (from AJCC 7th Ed.)


name: Juvenile Arthritis, Unspecified, Other Specified Site

description: Evidence of unspecified juvenile arthritis, other specified site.


Thyroid Cancer pT4a TNM Finding v7

description: Thyroid cancer with moderately advanced local disease.  Tumor of any size extending beyond the thyroid gland capsule to invade subcutaneous soft tissues, larynx, trachea, esophagus, or recurrent laryngeal nerve. (from AJCC 7th Ed.)


name: Grade 4 Atrioventricular Block Complete, CTCAE

description: Life-threatening consequences; urgent intervention indicated


name: Vaginal Cancer Clinical Distant Metastasis TNM Finding v8

description: A clinical finding about one or more characteristics of vaginal cancer, following the rules of the TNM AJCC v8 classification system as they pertain to distant metastases.