Loss of Range of Motion

description: A finding that the flexibility of a joint is below the expected range of normal for that individual.


Neonatal infectious disorder

category: biolink:Disease biolink:DiseaseOrPhenotypicFeature biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing

description: An infectious disorder that occurs during the neonatal period. Representative examples include streptococcal infection, E.coli infection, and bacterial meningitis.


Grade 4 Hypophosphatemia, CTCAE

category: biolink:PhenotypicFeature biolink:DiseaseOrPhenotypicFeature biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing

description: Life-threatening consequences


name: Anemia Complicating Pregnancy, Second Trimester

description: Evidence of anemia complicating pregnancy in the second trimester.


Cutaneous Melanoma TNM Finding v7

description: A finding about one or more characteristics of cutaneous melanoma, following the rules of the TNM AJCC v7 classification system.  The TNM clinical and pathologic regional lymph nodes tumor classifications of cutaneous melanoma are not the same. (from AJCC 7th Ed.)


Resectable Glioblastoma

description: A glioblastoma that is amenable to surgical resection.


Pelvis Cancer pT4a TNM Finding v8

description: Pelvis cancer with tumor involving the sacroiliac joint and extending medial to the sacral neuroforamen. (from AJCC 8th Ed.)


name: Grade 3 Sinus Intra-Operative Injury, CTCAE


Grade 2 Ataxia, CTCAE

description: Moderate symptoms; limiting instrumental ADL


name: New Onset Atrial Flutter Related to COVID-19

description: Newly occurring atrial flutter in a patient with probable or confirmed acute COVID-19.


description: Evidence of cocaine abuse with cocaine-induced sexual dysfunction.


name: Rheumatoid Arthritis of Unspecified Elbow with Involvement of Organs and Systems

description: Evidence of rheumatoid arthritis of unspecified elbow with involvement of organs and systems.


Locally Advanced Non-Cutaneous Melanoma

description: Non-cutaneous melanoma that has spread from its original site of growth to nearby tissues or lymph nodes.


name: Uterine Corpus Leiomyosarcoma and Endometrial Stromal Sarcoma pN0(i+) TNM Finding v8

description: Uterine corpus leiomyosarcoma or endometrial stromal sarcoma with isolated tumor cells in regional lymph node(s) no greater than 0.2 mm. (from AJCC 8th Ed.)


name: Endometrial Mucinous Adenocarcinoma, Intestinal-Type

description: A rare mucinous adenocarcinoma arising from intestinal metaplasia of the endometrium.


name: Maxillary Sinus Cancer pN2b TNM Finding v6 and v7

description: Maxillary sinus cancer with metastasis in multiple ipsilateral lymph nodes, none more than 6 cm in greatest dimension. (from AJCC 6th and 7th Eds.)


Blood Cardiac Troponin T Increased

description: A laboratory test result which indicates increased levels of cardiac troponin T in a biological specimen.


name: Carcinoma of the Conjunctiva Pathologic Regional Lymph Nodes TNM Finding v7

description: A pathologic finding about one or more characteristics of carcinoma of the conjunctiva, following the rules of the TNM AJCC v7 classification system as they pertain to staging of regional lymph nodes.


Lichen planus-like keratosis

description: A benign intraepidermal squamoproliferative neoplasm characterized by irregular acanthosis, hyperkeratosis, parakeratosis, and prominent chronic inflammation.


Persistent Disease

description: A disease that does not go to remission despite treatment.


Dog Bite

description: A wound received from the teeth of a dog.


Grade 4 Colitis, CTCAE

description: Life-threatening consequences; urgent intervention indicated


name: Grade 3 Colon Intra-Operative Injury, CTCAE


Secondary malignant neoplasm of skin

description: The spread of a malignant neoplasm to the skin.  This may be from a primary skin malignant neoplasm, or from a malignant neoplasm at a distant site.


name: Stage I Centroblastic Follicular Lymphoma

description: Ann Arbor Classification: Stage I: Involvement of a single lymph node region (I); or localized involvement of a single extralymphatic organ or site in the absence of any lymph node involvement (IE).


name: Rheumatoid Polyneuropathy with Rheumatoid Arthritis of Unspecified Site

description: Evidence of rheumatoid polyneuropathy with rheumatoid arthritis of unspecified site.


name: Malignant Neoplasm of Lower Respiratory Tract, Part Unspecified

description: Evidence of a malignant neoplasm of the lower respiratory tract, part unspecified.


name: Intraoperative Neurological Injury, CTCAE

description: A finding of damage to the nervous system during a surgical procedure.


name: Hypopharyngeal Cancer Pathologic Primary Tumor TNM Finding v8

description: A pathologic finding about one or more characteristics of hypopharyngeal cancer, following the rules of the TNM AJCC v8 classification system as they pertain to staging of the primary tumor.


Adrenal Cancer pT3 TNM Finding v7

description: Adrenal cancer with tumor of any size with local invasion, without invasion of adjacent organs.  Adjacent organs include kidney, diaphragm, great vessels, pancreas, spleen, and liver. (from AJCC 7th Ed.)


name: Female Reproductive System Precancerous Condition

description: A precancerous lesion that arises from the female reproductive system. Representative examples include atypical endometrial hyperplasia, endometrial intraepithelial neoplasia, and cervical intraepithelial neoplasia.


name: Juvenile Rheumatoid Arthritis with Systemic Onset, Right Knee

description: Evidence of juvenile rheumatoid arthritis with systemic onset in the right knee.


name: Grade 3 Blood and Lymphatic System Disorders - Other, Specify, CTCAE

description: Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL


Recurrence in Pelvic Nodes

description: A recurrence of disease in the pelvic lymph nodes.


Primary Bone Hodgkin Lymphoma

description: An exceedingly rare Hodgkin lymphoma that arises from the bone, without lymph node or other extranodal involvement.


name: Grade 3 Peristomal Infection with Unknown Absolute Neutrophil Count, CTCAE


name: Male Penile Urethra and Female Urethra Cancer pT4 TNM Finding v8

description: Urethral cancer with tumor invading other adjacent organs (e.g., invasion of the bladder wall). (from AJCC 8th Ed.)


Cutaneous Melanoma pN2a TNM Finding v7

description: Cutaneous melanoma with micrometastases in 2-3 regional lymph nodes.  Micrometastases are diagnosed after sentinel lymph node biopsy and completion of lymphadenectomy (if performed). (from AJCC 7th Ed.)


name: Grade 4 Hearing Patients without Baseline Audiogram and Not Enrolled in a Monitoring Program, CTCAE


Lip Pain

description: Painful sensation in the lip.


name: Other Pre-Existing Diabetes Mellitus in the Puerperium

description: Evidence of other pre-existing diabetes mellitus in the puerperium not specified elsewhere.


name: Malignant Neoplasm of Upper-Inner Quadrant of Right Male Breast

description: Evidence of a malignant neoplasm of the upper-inner quadrant of right male breast.


Glaucoma, CTCAE

description: A disorder characterized by an increase in pressure in the eyeball due to obstruction of the aqueous humor outflow.


Arthritis NOS aggravated

description: Exacerbation of an arthritic condition.


name: Merkel Cell Carcinoma pNX TNM Finding v8

description: Merkel cell carcinoma in which the regional lymph nodes cannot be assessed (e.g., previously removed for another reason or not removed for pathologic evaluation). (from AJCC 8th Ed.)


name: Localized Pancreatic Ductal Adenocarcinoma

description: A pancreatic ductal adenocarcinoma that has not spread to other anatomic sites.


Felty's Syndrome, Unspecified Wrist

description: Evidence of Felty's syndrome in an unspecified wrist.


Virologic Partial Response

description: The subject remains viremic during the treatment period and the decrease in viral load from baseline at a specified timepoint is above a predetermined threshold.


Grade 2 Purpura, CTCAE

description: Combined area of lesions covering 10-30% BSA; bleeding with trauma


CDH1 Gene Mutation Negative

description: A genetic finding indicating that CDH1 gene mutations have not been detected in a sample.


Fusion-Positive Rhabdomyosarcoma

description: A rhabdomyosarcoma characterized by the presence of chromosomal translocation t(1;13)(p36;q14) that results in PAX7-FOXO1 gene fusion; or translocation t(2;13)(q35;q14) that results in PAX3-FOXO1 gene fusion.


Adult Anaplastic Astrocytoma

description: An astrocytoma occurring in adults that is characterized by the presence of high mitotic activity, cytologic atypia, and architectural distortion.


name: Nasopharyngeal Cancer Pathologic Regional Lymph Nodes TNM Finding v8

description: A pathologic finding about one or more characteristics of nasopharyngeal cancer, following the rules of the TNM AJCC v8 classification system as they pertain to staging of regional lymph nodes.


description: Evidence of cannabis dependence with cannabis-induced anxiety disorder.


name: Glottic Cancer pT1b TNM Finding v6 and v7

description: Glottic cancer with tumor involving both vocal cords. (from AJCC 6th and 7th Eds.)


name: Developmental and Epileptic Encephalopathy 85 with or without Midline Brain Defects

description: An X-linked dominant subtype of developmental and epileptic encephalopathy caused by mutation(s) in the SMC1A gene,  encoding structural maintenance of chromosomes protein 1A.


Bladder Cancer pTa TNM Finding v8

description: Bladder cancer with a finding of non-invasive papillary carcinoma. (from AJCC 8th Ed.)


name: Locally Advanced Digestive System Neuroendocrine Carcinoma

description: A neuroendocrine carcinoma that arises from any part of the digestive system and has spread to nearby tissues or lymph nodes.


Factor XI Inactivation

description: Presence of inactivating antibodies to factor XI in the blood.


name: Skin Squamous Cell Carcinoma or Other Skin Carcinomas Pathologic Primary Tumor TNM Finding v7

description: A pathologic finding about one or more characteristics of skin squamous cell carcinoma or other skin carcinomas, following the rules of the TNM AJCC v7 classification system as they pertain to staging of the primary tumor.  It excludes cutaneous squamous cell carcinoma of the eyelid and Merkel cell carcinoma.  The TNM pathologic and clinical primary tumor classifications of skin squamous cell carcinoma or other skin carcinomas are the same. (from AJCC 7th Ed.)


name: Likely Tumor Complete Metabolic Response

description: A finding of diffuse metabolic activity at the primary tumor or nodal sites that is greater than background uptake but less than liver uptake.


name: Childhood Malignant Kidney Neoplasm Excluding Renal Cell Carcinoma by Toronto Guidelines v2 Stage, International Society of Pediatric Oncology (SIOP) Protocol

description: A term that refers to the staging of childhood malignant kidney neoplasms excluding renal cell carcinoma, according to the Toronto childhood cancer staging guidelines v2, International Society of Pediatric Oncology (SIOP) protocol. It is based on findings at surgery for patients who have received chemotherapy prior to surgery. (Childhood cancer staging for population registries according to the Toronto Childhood Cancer Stage Guidelines - Version 2. Cancer Council Queensland and Cancer Australia: Brisbane, Australia; 2021.)


Grade 2 Anxiety, CTCAE

description: Moderate symptoms; limiting instrumental ADL


name: Rheumatoid Polyneuropathy with Rheumatoid Arthritis of Unspecified Knee

description: Evidence of rheumatoid polyneuropathy with rheumatoid arthritis of unspecified knee.


Cutaneous Melanoma cM1a TNM Finding v7

description: Cutaneous melanoma with metastases to skin, subcutaneous tissues, or distant lymph nodes associated with normal serum lactate dehydrogenase (LDH). (from AJCC 7th Ed.)


Grade 5 Hypoalbuminemia, CTCAE

description: Death


name: Grade 1 Duodenum Intra-Operative Injury, CTCAE


Extrahepatic Bile Duct Carcinoid Tumor

description: A well differentiated, low grade neuroendocrine neoplasm that arises from the extrahepatic bile ducts. The mitotic count is less than 2 per 10 HPF and/or the Ki67 index is equal to or less than 2 percent.


Vaginal Cancer by AJCC v7 Stage

description: A term that refers to the staging of vaginal cancer according to the American Joint Committee on Cancer, 7th edition.


name: Pancreatic Neuroendocrine Tumor Pathologic Primary Tumor TNM Finding v8

description: A pathologic finding about one or more characteristics of a pancreatic neuroendocrine tumor, following the rules of the TNM AJCC v8 classification system as they pertain to staging of the primary tumor.


Pure Erythroid Leukemia

description: Acute erythroid leukemia characterized by the presence of immature erythroid cells in the bone marrow (at least 80% of the cellular component), without evidence of a significant myeloblastic cell population present.


Paratesticular Mucinous Cystadenoma

description: A rare mucinous cystadenoma that arises from the paratesticular structures.


name: Blood Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


Benign neoplasm of liver

description: A neoplasm that arises from the liver and is characterized by the absence of atypical or malignant cytological and architectural features, and absence of invasive features or metastatic potential.


name: Grade 2 Peripheral Nerve Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


name: Pancreas Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


H influenze type B Meningitis

description: Meningitis that is attributed to the bacteria H influenze type B.


name: Grade 1 Ovary Intra-Operative Injury, CTCAE


Urothelial carcinoma ureter recurrent

description: The reemergence of ureter urothelial carcinoma after a period of remission.


name: Grade 1 Thyroid Intra-Operative Injury, CTCAE


name: Grade 2 Recurrent Laryngeal Nerve Intra-Operative Injury, CTCAE


Cervical Cancer pT2 TNM Finding v9

description: Cervical carcinoma invading beyond the uterus but not to the pelvic wall or to lower third of vagina. (from AJCC 9th Ed.)


name: Grade 4 Neonatal Intraventricular Hemorrhage, AE

description: An adverse event in a newborn characterized by intraventricular hemorrhage with parenchymal venous infarction; resulting in life threatening consequences (e.g. refractory seizures, hypotension, respiratory depression); requiring urgent stabilization or surgical decompression.


name: Drug or Chemical Induced Diabetes Mellitus with Other Skin Ulcer

description: Evidence of drug or chemical induced diabetes mellitus with other skin ulcer.


name: Other Epilepsy, not Intractable, with Status Epilepticus

description: Evidence of other epilepsy with status epilepticus that has some acceptable treatment options not specified elsewhere.


name: Grade 2 Catheter-Related Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


Stage IA Testicular Cancer AJCC v8

description: Stage IA includes: pT1, N0, M0, S0. pT1: Testicular cancer which is limited to testis (including rete testis invasion) without lymphovascular invasion. N0: Testicular cancer with no regional lymph node metastasis. M0: Testicular cancer without evidence of distant metastasis. S0: Marker study levels within normal limits. (AJCC 8th ed.)


name: Lip and Oral Cavity Cancer cN2c TNM Finding v8

description: Lip and oral cavity cancer with metastases in bilateral or contralateral lymph nodes, none larger than 6 cm in greatest dimension, and ENE(-). (from AJCC 8th Ed.)


name: Rheumatoid Arthritis without Rheumatoid Factor, Left Shoulder

description: Evidence of rheumatoid arthritis without rheumatoid factor in the left shoulder.


name: Grade 1 Liver Intra-Operative Injury, CTCAE


Stage II Cervical Cancer AJCC v8

description: Stage II includes: T2, Any N, M0. T2: Cervical carcinoma invading beyond the uterus but not to the pelvic wall or to lower third of vagina. M0: No distant metastasis. (AJCC 8th Ed.)


Furnace or Boiler Smoke Exposure

description: Environmental, occupational or consumer-based exposure to airborne gases and particulates emitted by a boiler or furnace.


Rhinocephaly

description: A congenital anatomic defect characterised by the presence of a proboscis-like nose located above the eyes, which are partially or completely fused.


name: Grade 5 Bladder Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


name: Grade 4 Upper Respiratory Infection, CTCAE

description: Life-threatening consequences; urgent intervention indicated


Lassitude

description: Physical or mental fatigue.


name: Stage IV Adrenal Gland Pheochromocytoma and Sympathetic Paraganglioma AJCC v8

description: Stage IV includes: Any T, Any N, M1. M1: Distant metastasis. (from AJCC 8th Ed.)


Post procedural hemorrhage

description: Bleeding occurring after a medical intervention.


name: Psychomotor Deficit following Cerebral Infarction

description: Evidence of psychomotor deficit following cerebral infarction.


Condyloma acuminata of vulva

description: A benign human papillomavirus-related neoplasm that arises from the vulva. It is characterized by the presence of papillary structures with fibrovascular cores covered by stratified squamous epithelium showing koilocytotic changes.


Upper Aerodigestive Invasive Malignancy

description: A finding indicating the presence of an invasive upper aerodigestive tract malignancy.


name: Nasal Cavity and Paranasal Sinuses Cancer cN0 TNM Finding v8

description: Nasal cavity and paranasal sinuses cancer with no metastasis to regional lymph nodes. (from AJCC 8th Ed.)


Bone Cancer pM1b TNM Finding v8

description: Bone cancer with metastasis in the bone or other distant sites. (from AJCC 8th Ed.)


name: Lugano Classification Stage IIE Adult Lymphoma AJCC v8

description: Stage IIE: Contiguous extralymphatic extension from a nodal site with or without involvement of other lymph node regions on the same side of the diaphragm. (from AJCC 8th Ed.)


name: Grade 5 Thrombotic Microangiopathy, CTCAE


Body Mass Index 25 or Greater

description: Indicates a body mass index measurement of 25 or higher.


Premature Menopause, CTCAE

description: A disorder characterized by premature ovarian failure. Symptoms may include hot flashes, night sweats, mood swings, and a decrease in sex drive. Laboratory findings include elevated luteinizing hormone (LH) and follicle-stimulating hormone (FSH.)


name: Testicular Cancer Pathologic Distant Metastasis TNM Finding v7

description: A pathologic finding about one or more characteristics of testicular cancer, following the rules of the TNM AJCC v7 classification system as they pertain to distant metastases.  There is no pathologic M0 for testicular cancer. (from AJCC 7th Ed.)


name: Left Apical Anterior Fibromuscular Stroma of Prostate

description: The portion of the fibromuscular stroma of the prostate that is located on the anatomical left side of the apical division of the anterior lobe.


name: Other Acute Monocytic Leukemia in Relapse

description: Evidence of other acute monocytic leukemia in relapse not specified elsewhere.


Grade 3 Bone Infection, CTCAE

description: IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated


name: High Grade Anal Intraepithelial Neoplasia

description: Anal canal or perianal skin intraepithelial neoplasia with moderate or severe dysplasia.


Stage 0 Merkel Cell Carcinoma AJCC v7

description: Stage 0 includes: Tis, N0, M0.  Tis: In situ primary tumor.  N0: No regional lymph node metastasis.  M0: No distant metastasis.  (AJCC 7th ed.)


name: Childhood Lymphocyte-Rich Classic Hodgkin Lymphoma

description: Lymphocyte-rich classic Hodgkin lymphoma occurring in childhood.


Kaposi sarcoma of right lung

description: Evidence of Kaposi's sarcoma of the right lung.


Mandibular Buccal Bifurcation Cyst

description: An inflammatory collateral cyst that arises on the lower first or second molars. (WHO 2017)


Grade 3 Corneal Ulcer, CTCAE

description: Corneal ulcer without perforation in the affected eye


name: Intrahepatic Bile Duct Cancer pT4 TNM Finding v7

description: Intrahepatic bile duct cancer with periductal invasion. (from AJCC 7th Ed.)


Grade 1 Cataract, CTCAE

description: Asymptomatic; clinical or diagnostic observations only; intervention not indicated


Involved Circumferential Margin by MRI

description: The determination by MRI of the presence of neoplastic tissue outside of a circumferential resection margin.


name: Mantle Cell Lymphoma, Intrathoracic Lymph Nodes

description: Evidence of mantle cell lymphoma in the intrathoracic lymph nodes.


name: Grade 4 Urethra Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


Sleep Apnea, CTCAE

description: A disorder characterized by cessation of breathing for short periods during sleep.


name: Grade 5 Cranial Nerve II Neuropathy, CTCAE


name: Monoplegia of Upper Limb following Non-Traumatic Intracerebral Hemorrhage Affecting Unspecified Side

description: Evidence of monoplegia of upper limb following non-traumatic intracerebral hemorrhage affecting unspecified side.


Lung Cancer pM1c TNM Finding v8

description: Lung cancer with multiple extrathoracic metastases in a single organ or in multiple organs. (from AJCC 8th Ed.)


pT2b TNM Finding

description: A pathologic primary tumor TNM finding. The definition of pT2b finding depends on the particular type of cancer that it refers to; for example, for prostate cancer, pT2b finding is defined as follows: cancer involving more than one-half of one lobe, but not both lobes of the prostate gland; for lung cancer, pT2b finding is defined as follows: cancer with a tumor size more than 5 cm but 7 cm or less in greatest dimension. (from AJCC 7th Ed.)


Recurrent Biliary Tract Carcinoma

description: The reemergence of a carcinoma arising from any part of the biliary tract after a period of remission.


name: Gallbladder Flat Biliary Intraepithelial Neoplasia

description: Biliary intraepithelial neoplasia that affects the gallbladder epithelium.  It is characterized by the absence of intraluminal micropapillary projections.


name: Atherosclerosis of Unspecified Type of Bypass Graft(s) of Left Leg with Ulceration of Heel and Midfoot

description: Evidence of atherosclerosis of unspecified type of bypass graft(s) of left leg with ulceration of heel and midfoot.


Midgut Neuroendocrine Tumor G3

description: A neuroendocrine tumor grade 3 that arises from the jejunum, ileum, proximal colon, or appendix.


name: Grade 2 Fibrosis-Deep Connective Tissue, CTCAE


Grade 2 Laryngeal Obstruction, CTCAE

description: Symptomatic (e.g., noisy airway breathing), no respiratory distress; medical intervention indicated (e.g., steroids); limiting instrumental ADL


Chronic Bullous Disease of Childhood

description: A blistering disorder characterized by linear deposition of IgA at the dermoepidermal junction.


name: Acute Leukemia of Unspecified Cell Type not Having Achieved Remission

description: Evidence of acute leukemia of unspecified cell type not having achieved remission.


Grade 2 Prolapse of Urostomy, CTCAE

description: Local care or maintenance; minor revision indicated


name: Myelodysplastic and myeloproliferative neoplasm with SF3B1 mutation and thrombocytosis

description: A myelodysplastic/myeloproliferative neoplasm characterized by thrombocytosis, anemia, blasts less than 5% in bone marrow and less than 1% in peripheral blood, presence of SF3B1 gene mutation, absence of BCR/ABL fusion, absence of genetic abnormalities associated with myeloid/lymphoid neoplasms with eosinophilia and tyrosine kinase gene fusions, and no history of other myelodysplastic/myeloproliferative neoplasms or myeloproliferative neoplasms and myelodysplastic syndromes.


name: Grade 5 Pelvis Infection NOS Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


Vaginal Cancer by AJCC v6 Stage

description: A term that refers to the staging of vaginal cancer according to the American Joint Committee on Cancer, 6th edition.


name: Cytogenetically Normal Acute Myeloid Leukemia Post Cytotoxic Therapy

description: Acute myeloid leukemia not associated with cytogenetic abnormalities and arising as a result of the mutagenic effect of chemotherapy and/or ionizing radiation.


Grade 4 Ileal Fistula, CTCAE

description: Life-threatening consequences; urgent intervention indicated


Laryngeal Inflammation, CTCAE

description: A disorder characterized by an inflammation involving the larynx.


name: Grade 5 Persistent Pulmonary Hypertension of the Newborn, AE

description: A persistent pulmonary hypertension adverse event in a newborn which results in death.


name: Unresectable Digestive System Neuroendocrine Tumor G3

description: Digestive system neuroendocrine tumor G3 that is not amenable to surgical resection.


name: Unknown Primary Tumor cN3a TNM Finding v8

description: Unknown primary tumor with metastasis in a cervical lymph node larger than 6 cm in greatest dimension and ENE(-). (from AJCC 8th Ed.)


Childhood Grade II Meningioma

description: A grade II meningioma that occurs during childhood.


Stage IIB Testicular Cancer AJCC v8

description: Stage IIB includes: (Any pT/TX, N2, M0, S0); (Any pT/TX, N2, M0, S1). TX: Testicular cancer in which the primary tumor cannot be assessed. N2: Testicular cancer with metastasis with a lymph node mass larger than 2 cm but not larger than 5 cm in greatest dimension; or more than five nodes positive, none larger than 5 cm; or evidence of extranodal extension of tumor. M0: Testicular cancer without evidence of distant metastasis. S0: Marker study levels within normal limits. S1: LDH less than 1.5 x N and hCG (mlU/mL) less than 5,000 and AFP (ng/mL) less than 1,000. N indicates the upper limit of normal for the LDH assay. (AJCC 8th ed.)


Bacterial Zoonoses

description: A bacterial infection that is transmitted from animals to people.


name: Grade 3 Neck NOS Intra-Operative Injury, CTCAE


name: Cranial Nerve Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


Preexisting Condition

description: A health condition or medical problem that was diagnosed or treated before a specific date.


Lymph Leakage, CTCAE

description: A disorder characterized by the loss of lymph fluid into the surrounding tissue or body cavity.


name: Nasopharyngeal Cancer pT4 TNM Finding v8

description: Nasopharyngeal cancer with intracranial extension, involvement of cranial nerves, hypopharynx, orbit, parotid gland, and/or extensive soft tissue infiltration beyond the lateral surface of the lateral pterygoid muscle. (from AJCC 8th Ed.)


Flu-Like Symptoms

description: Complaints describing a pattern similar to influenza, which may include one or more of the following symptoms: fever, chills, muscle or body aches, cough, sore throat, rhinitis, or fatigue.


name: Mucosal Melanoma of the Genitourinary System

description: A malignant melanocytic neoplasm that arises from a mucosal site of the genitourinary system.


name: Grade 5 Ungual Infection with Unknown Absolute Neutrophil Count, CTCAE


name: Eyelid Carcinoma Pathologic Primary Tumor TNM Finding v8

description: A pathologic finding about one or more characteristics of eyelid carcinoma, following the rules of the TNM AJCC v8 classification system as they pertain to staging of the primary tumor.


name: Grade 4 Biliary Tree Stricture or Stenosis, CTCAE


name: Localization-Related Symptomatic Epilepsy and Epileptic Syndromes with Simple Partial Seizures, not Intractable, without Status Epilepticus

description: Evidence of localization-related symptomatic epilepsy and epileptic syndromes with simple partial seizures without status epilepticus that responds to treatment.


Bladder Spasm, CTCAE 5.0

description: A disorder characterized by a sudden and involuntary contraction of the bladder wall.


Rheumatoid Nodule, Left Ankle and Foot

description: Evidence of rheumatoid nodule in the left ankle and foot.


name: Other Paralytic Syndrome following Non-Traumatic Subarachnoid Hemorrhage, Bilateral

description: Evidence of other paralytic syndrome following non-traumatic subarachnoid hemorrhage that is bilateral not specified elsewhere.


Grade 1 Dyspareunia, CTCAE

description: Mild discomfort or pain associated with vaginal penetration; discomfort relieved with use of vaginal lubricants or estrogen


Bone Tuberculosis

description: Tuberculosis of the bone.


name: Acute Myeloid Leukemia Arising from Previous Myelodysplastic Syndrome

description: An acute myeloid leukemia developing in patients with a prior history of myelodysplastic syndrome.


Refractory Malignant Mastocytosis

description: Malignant mastocytosis that is resistant to treatment.


Recurrent Ependymoma

description: The reemergence of ependymoma after a period of remission.


Malposition of Ureter

description: Orientation of a ureter in an unusual anatomic location.


name: Grade 1 Allergic Rhinitis Including Sneezing Nasal Stuffiness Postnasal Drip, CTCAE


name: Adrenal Cortical Carcinoma pT1 TNM Finding v8

description: Tumor measuring 5 cm or less in greatest dimension, with no extra-adrenal invasion. (from AJCC 8th Ed.)


name: Grade 4 Esophagus Intra-Operative Injury, CTCAE


name: Glioblastoma with Primitive Neuronal Component

description: A glioblastoma characterized by the presence of well-demarcated nodules which contain primitive cells exhibiting neuronal differentiation.


Cutaneous Melanoma pN1a TNM Finding v7

description: Cutaneous melanoma with micrometastasis in one regional lymph node.  Micrometastases are diagnosed after sentinel lymph node biopsy and completion of lymphadenectomy (if performed). (from AJCC 7th Ed.)


name: Grade 4 Toxic Epidermal Necrolysis, CTCAE

description: Skin sloughing covering >=30% BSA with associated symptoms (e.g., erythema, purpura, or epidermal detachment)


other early-onset cerebellar ataxia

description: Evidence of other early-onset cerebellar ataxia not specified elsewhere.


Congenital Phrenic Nerve Palsy

description: Damage to the phrenic nerve that results in paralysis of the hemidiaphragm at birth.


name: Duodenum and Ampulla of Vater Neuroendocrine Tumor pM1 TNM Finding v8

description: Duodenum and ampulla of Vater neuroendocrine tumor with distant metastasis. (from AJCC 8th Ed.)


Cervical Cancer cT0 TNM Finding v7

description: Cervical cancer with no evidence of primary tumor. (from AJCC 7th Ed.)


Stage III Prostate Cancer AJCC v7

description: Stage III includes: T3a-b, N0, M0, Any PSA, Any Gleason.  cT3a: Tumor with extracapsular extension (unilateral or bilateral).  pT3a: Tumor with extraprostatic extension or microscopic invasion of bladder neck.  T3b: Tumor invades seminal vesicle(s).  cN0: No regional lymph node metastasis.  pN0: No positive regional nodes.  M0: No distant metastasis.  (AJCC 7th ed.)


Hemoglobin Beta Normal Genotype

description: A genetic finding indicating that both copies of chromosome 16 each have one functional copy of the hemoglobin beta (HBB) gene. This genotype is characterized by normal beta globin production.


Refractory Small Cell Glioblastoma

description: A small cell glioblastoma that is resistant to treatment.


name: FIGO Stage IC Gestational Trophoblastic Tumor


Mass

description: A benign or malignant pathologic structure in any part of the body, resulting from a neoplastic accumulation of cells, inflammatory cells, or cystic changes.


name: Carcinoma in situ of other specified sites

description: Evidence of carcinoma in situ of other specified sites.


Stage IA Cervical Cancer AJCC v8

description: Stage IA includes: T1a, Any N, M0. T1a: Tumor diagnosed only by microscopy. Stromal invasion with a maximum depth of 5.0 mm measured from the base of the epithelium and a horizontal spread of 7.0 mm or less. Vascular space involvement, venous or lymphatic, does not affect classification. M0: No distant metastasis. (AJCC 8th Ed.)


name: Sarcoma of the Orbit Pathologic TNM Finding v7

description: A pathologic finding about one or more characteristics of sarcoma of the orbit, following the rules of the TNM AJCC v7 classification system.  The nature of the histopathology specimen (fine-needle aspiration biopsy, excisional biopsy, lumpectomy, or total excision) should be noted.  Pathologic classification is based on the specific histopathology of the tumor, its differentiation (grade), and the extent of removal (evaluation of the excisional margins).  In total excision specimens, evaluation of the surgical margins is mandatory.  (from AJCC 7th Ed.)


Stage IVB Bladder Cancer AJCC v8

description: Stage IVB includes: Any T, Any N, M1b. M1b: Non-lymph node distant metastases. (AJCC 8th ed.)


name: Malignant Neoplasm of Scapula and Long Bones of Right Upper Limb

description: Evidence of a malignant neoplasm of the scapula and long bones of right upper limb.


Colorectal Cancer TNM Finding v6

description: A finding about one or more characteristics of colorectal cancer, following the rules of the TNM AJCC v6 classification system.


Pelvis Cancer pT2b TNM Finding v8

description: Pelvis cancer with tumor confined to one pelvic segment with extraosseous extension or two segments without extraosseous extension and measuring more than 8 cm in greatest dimension. (from AJCC 8th Ed.)


name: Male Penile Urethra and Female Urethra Cancer pT3 TNM Finding v8

description: Urethral cancer with tumor invading any of the following: corpus cavernosum, anterior vagina. (from AJCC 8th Ed.)


name: Pleural Malignant Mesothelioma pT2 TNM Finding v8

description: Pleural malignant mesothelioma with tumor involving each of the ipsilateral pleural surfaces (parietal, mediastinal, diaphragmatic, and visceral pleura) with at least one of the following features: involvement of diaphragmatic muscle and/or extension of tumor from visceral pleura into the underlying pulmonary parenchyma. (from AJCC 8th Ed.)


name: Musculoskeletal Chest Pain due to Slipping Rib Syndrome

description: A condition in which there is musculoskeletal chest pain associated with one or more ribs subluxing from the joint. (ACC/AHA)


name: Bone Cancer Pathologic Distant Metastasis TNM Finding v7

description: A pathologic finding about one or more characteristics of bone cancer, following the rules of the TNM AJCC v7 classification system as they pertain to distant metastases.  There is no pathologic M0 for bone cancer.


Genetic anomaly of leukocyte

description: An abnormality of leukocytes, the cause of which is present from birth.


name: Generic Regional Lymph Nodes TNM Finding


Weight Gain Due to Fluid Retention

description: A finding of rapid weight gain due to fluid retention.


Necrotizing granulomatous inflammation

description: A granuloma that contains areas of necrosis.  The majority of cases are of infectious origin.


name: Other Rheumatoid Arthritis with Rheumatoid Factor of Left Hip

description: Evidence of other rheumatoid arthritis with rheumatoid factor of left hip not specified elsewhere.


name: Other Atherosclerosis of Autologous Vein Bypass Graft(s) of the Extremities, Right Leg

description: Evidence of other atherosclerosis of autologous vein bypass graft(s) of the extremities in the right leg not specified elsewhere.


Grade 3 Gastric Stenosis, CTCAE

description: Severely altered GI function; tube feeding or hospitalization indicated; elective operative intervention indicated


name: Type 2 diabetes mellitus with diabetic cataract

description: Evidence of type 2 diabetes mellitus with diabetic cataract.


Delirium, CTCAE

description: A disorder characterized by the acute and sudden development of confusion, illusions, movement changes, inattentiveness, agitation, and hallucinations. Usually, it is a reversible condition.


name: Fallopian Tube Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


name: Unspecified Atherosclerosis of Native Arteries of Extremities, Bilateral Legs

description: Evidence of unspecified atherosclerosis of native arteries of extremities in both legs.


name: Hepatitis B Virus Surface Antigen Negative

description: An indication that the hepatitis B virus surface protein antigen has not been detected in a sample.


name: Left Anterior Middle Peripheral Zone of Prostate

description: The region of the prostate that is located on the anatomical left side of the anterior portion of the middle division of the peripheral zone.


name: Grade 2 Partial Thromboplastin Time, CTCAE


name: Recurrent major depression in full remission

description: Evidence of major depressive disorder that is recurrent and in full remission.


name: Oropharyngeal (p16-Negative) Cancer pM1 TNM Finding v8

description: Oropharyngeal (p16-negative) cancer with distant metastasis. (from AJCC 8th Ed.)


Squamous cell papilloma of eyelid

description: A papilloma that arises from the eyelid. It is composed of squamous cells and is characterized by the presence of an acanthotic epithelium with hyperkeratosis and papillary projections with an inner fibrovascular core. It is the most common benign epithelial tumor of eyelid. It usually affects middle-aged or older adults.


name: Stomach Infection with Unknown Absolute Neutrophil Count, CTCAE


name: Carcinoma in Situ of Unspecified Urinary Organ

description: Evidence of carcinoma in situ of unspecified urinary organ.


name: Combined Rheumatic Disorders of Mitral, Aortic and Tricuspid Valves

description: Evidence of combined rheumatic disorders of mitral, aortic and tricuspid valves.


name: Grade 5 Metabolic or Respiratory Acidosis, CTCAE


name: Forced Expiratory Volume Decreased, CTCAE

description: A finding based on test results that indicate a relative decrease in the fraction of the forced vital capacity that is exhaled in a specific number of seconds.


Breast Cancer cT3 TNM Finding v6

description: Breast cancer with tumor size more than 5.0 cm in greatest dimension. (from AJCC 6th Ed.)


Ureter Cancer by AJCC v8 Stage

description: A term that refers to the staging of ureter cancer according to the American Joint Committee on Cancer, 8th edition. This staging system applies to ureter urothelial (transitional cell) carcinoma, including histologic variants micropapillary and nested subtypes. (from AJCC 8th Ed.)


Late-Onset Retinal Degeneration

description: An autosomal dominant condition caused by mutation in the C1QTNF5 gene, encoding complement C1q tumor necrosis factor-related protein 5. It is characterized by dark adaptation abnormalities, sub-retinal pigment epithelium lipid-rich material deposits, choroidal neovascularization, and chorioretinal atrophy. The typical onset is in the fifth or sixth decade of life.


name: Carcinoma in Situ of Unspecified Female Genital Organs

description: Evidence of carcinoma in situ of unspecified female genital organs.


Hepatic Fibrosis, Early Fibrosis

description: Evidence of hepatic fibrosis, early fibrosis.


Solid Lesion

description: A lesion that does not contain liquid or cystic areas.


Cotinine Less than 30 ng/ml

description: A semiquantitative finding indicating that the concentration of cotinine in a sample is less than 30 ng/mL.


Malignant neoplasm of stomach stage III

description: Stage III includes: IIIA (T4a, N1, M0); (T3, N2, M0); (T2, N3, M0); IIIB (T4b, N0, M0); (T4b, N1, M0); (T4a, N2, M0); (T3, N3, M0); IIIC (T4b, N2, M0); (T4b, N3, M0); (T4a, N3, M0).  T2: Tumor invades the muscularis propria. T3: Tumor penetrates subserosal connective tissue without invasion of visceral peritoneum or adjacent structures.  T4a: Tumor invades serosa (visceral peritoneum).  T4b: Tumor invades adjacent structures. N0: No regional lymph node metastasis.  N1: Metastasis in 1-2 regional lymph nodes.  N2: Metastasis in 3-6 regional lymph nodes.  N3: Metastasis in seven or more regional lymph nodes. M0: No distant metastasis.  (AJCC 7th ed.)


name: Malignant Neoplasm of Commissure of Lip, Unspecified

description: Evidence of a malignant neoplasm of the commissure of lip.


name: Lymphoma by Working Formulation (Antiquated)


name: Merkel Cell Carcinoma cN3 TNM Finding v8

description: Merkel cell carcinoma with in-transit metastasis (discontinuous from primary tumor; located between primary tumor and draining regional nodal basin, or distal to the primary tumor) with lymph node metastasis. (from AJCC 8th Ed.)


name: Grade 4 Alanine Aminotransferase Increased, CTCAE

description: >20.0 x ULN if baseline was normal; >20.0 x baseline if baseline was abnormal


Childhood Acute Leukemia

description: An acute leukemia that occurs during childhood.


name: Cutaneous Melanoma Clinical TNM Finding v6

description: A clinical finding about one or more characteristics of cutaneous melanoma, following the rules of the TNM AJCC v6 classification system. TNM clinical findings are based on information obtained prior to the first definitive treatment through physical examination, diagnostic imaging, endoscopy, biopsy or laboratory testing.


Gastric Poorly Cohesive Adenocarcinoma

description: An adenocarcinoma that arises from the gastric mucosa and is characterized by the presence of isolated malignant cells or malignant cells that form small aggregates.  This category includes signet ring cell adenocarcinomas, adenocarcinomas that are composed of malignant cells resembling lymphocytes and histiocytes, and adenocarcinomas that are composed of malignant cells with deeply eosinophilic cytoplasm.


Grade 1 Photosensitivity, CTCAE

description: Painless erythema and erythema covering <10% BSA


Terminal illness

description: An illness that has a prognosis of death.


Stage IIIA Gastric Carcinoma

description: Stage IIIA includes: (T4a, N1, M0); (T3, N2, M0); (T2, N3, M0).  T2: Tumor invades the muscularis propria. T3: Tumor penetrates subserosal connective tissue without invasion of visceral peritoneum or adjacent structures.  T4a: Tumor invades serosa (visceral peritoneum).  N1: Metastasis in 1-2 regional lymph nodes.  N2: Metastasis in 3-6 regional lymph nodes.  N3: Metastasis in seven or more regional lymph nodes. M0: No distant metastasis.  (AJCC 7th ed.)


Periventricular Leukomalacia, AE

description: An adverse event in a newborn characterized by a form of cerebral white matter injury usually seen in preterm infants that is characterized by necrotic degeneration or gliosis of white matter adjacent to the cerebral ventricles that may evolve into focal cysts.


Expected Adverse Event

description: Any adverse event associated with a medical product or procedure, whose nature and severity have been previously observed, identified in nature, severity, or frequency, and documented in the investigator brochure, investigational plan, protocol, current consent form, scientific publication, or in other relevant and reliable document. The old term Side Effect is retired and should not be used.


Off-resonance Effect

description: An artifact resulting from a signal which has a frequency different from that expected for the system.


name: Grade 3 Vein Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


name: Post-Dysenteric Arthropathy, Unspecified Hip

description: Evidence of post-dysenteric arthropathy in an unspecified hip.


Irritability, CTCAE

description: A disorder characterized by an abnormal responsiveness to stimuli or physiological arousal; may be in response to pain, fright, a drug, an emotional situation or a medical condition.


name: Hallucinogen Abuse with Hallucinogen Persisting Perception Disorder

description: Evidence of hallucinogen abuse with hallucinogen persisting perception disorder.


name: Grade 3 Peripheral Sensory Nerve NOS Intra-Operative Injury, CTCAE


Bacterial Colonization

description: The detection of bacteria in or on an anatomic site, medical device or biospecimen.


name: Cutaneous Squamous Cell Carcinoma of the Head and Neck cN3a TNM Finding v8

description: Cutaneous squamous cell carcinoma of the head and neck with metastasis in a lymph node larger than 6 cm in greatest dimension and ENE(-). (from AJCC 8th Ed.)


Stage III Bone Sarcoma AJCC v7

description: Stage III includes: T3, N0, M0, G3, G4. T3: Tumor more than 8 cm in greatest dimension.  N0: No regional lymph node metastasis.  M0: No distant metastasis.  G3: Poorly differentiated.  G4: Undifferentiated. (AJCC 7th ed.)


name: Arthropathy following Intestinal Bypass, Unspecified Ankle and Foot

description: Evidence of arthropathy following intestinal bypass in an unspecified ankle and foot.


Grade 5 Pulmonary Fibrosis, CTCAE

description: Death


name: Grade 3 Spinal Cord Intra-Operative Injury, CTCAE


name: Jejunum and Ileum Neuroendocrine Tumor cM1a TNM Finding v8

description: Jejunum and ileum neuroendocrine tumor with metastasis confined to liver. (from AJCC 8th Ed.)


Cervical Cancer cT2a1 TNM Finding v8

description: Cervical carcinoma invading beyond the uterus but not to the pelvic wall or to lower third of vagina without parametrial invasion. Clinically visible lesion 4.0 cm or less in greatest dimension. (from AJCC 8th Ed.)


Grade 2 Chest Pain - Cardiac, CTCAE

description: Moderate pain; pain on exertion; limiting instrumental ADL; hemodynamically stable


Mitochondrial enzyme deficiency

description: A constellation of disorders whose common thread is the insufficient quantity of one or more mitochondrial enzymes.


Grade 2 Ear Pain, CTCAE

description: Moderate pain; limiting instrumental ADL


name: Merkel Cell Carcinoma pM1 TNM Finding v8

description: Merkel cell carcinoma with distant metastasis microscopically confirmed. (from AJCC 8th Ed.)


Stage IIIC1 Cervical Cancer AJCC v9

description: Stage IIIC1 includes: TX, T0, T1-3, N1, M0. TX: Primary tumor cannot be assessed. T0: No evidence of primary tumor. T1: Tumor strictly confined to the cervix (extension to corpus should be disregarded). T2: Tumor invading beyond the uterus but not to the pelvic wall or to lower third of vagina. T3: Tumor extending to pelvic sidewall and/or involving the lower third of vagina, and/or causing hydronephrosis or nonfunctioning kidney. The pelvic sidewall is defined as the muscle, fascia, neurovascular structures, and skeletal portions of the bony pelvis. Cases with no cancer-free space between the tumor and pelvic wall by rectal examination are FIGO III. N1: Tumor with regional lymph node metastasis to pelvic lymph nodes only. M0: No distant metastasis. (from AJCC 9th Ed.)


name: Other Inflammatory Spondylopathies, Sacral/Sacrococcygeal Region

description: Evidence of other inflammatory spondylopathies in the sacral/sacrococcygeal region not specified elsewhere.


Bone Cancer pM1b TNM Finding v7

description: Bone cancer with metastasis to other distant sites. (from AJCC 7th Ed.)


name: Duodenum and Ampulla of Vater Neuroendocrine Tumor cM0 TNM Finding v8

description: Duodenum and ampulla of Vater neuroendocrine tumor without evidence of distant metastasis. (from AJCC 8th Ed.)


Lymphoma, Low-Grade

description: An antiquated term that refers to a non-Hodgkin lymphoma with low grade histologic features.


name: Grade 2 Infertility and Sterility, CTCAE


name: Grade 2 Central Nervous System Necrosis, CTCAE

description: Moderate symptoms; corticosteroids indicated


name: Radiation-Induced Malignant Peripheral Nerve Sheath Tumor

description: A malignant peripheral nerve sheath tumor that is the result of exposure to ionizing radiation.


name: Malignant Neoplasm of Overlapping Sites of Other and Ill-Defined Sites

description: Evidence of a malignant neoplasm of overlapping sites of the other and ill-defined sites.


description: Evidence of cannabis abuse with intoxication delirium.


name: Grade 3 Metabolism and Nutrition Disorders - Other, Specify, CTCAE

description: Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL


Jaccoud Arthropathy, Right Hand

description: Evidence of Jaccoud arthropathy in the right hand.


name: Other Classic Hodgkin Lymphoma, Intrathoracic Lymph Nodes

description: Evidence of other classic Hodgkin lymphoma in the intrathoracic lymph nodes not specified elsewhere.


Duodenal Obstruction, CTCAE

description: A disorder characterized by blockage of the normal flow of stomach contents through the duodenum.


Grade 2 Testosterone Deficiency, CTCAE

description: Replacement therapy initiated


name: Grade 3 Brain and Spinal Cord Infection with Unknown Absolute Neutrophil Count, CTCAE


Surgical Finding

description: A finding or observation that is made during surgery.


Grade 2 Facial Nerve Disorder, CTCAE

description: Moderate symptoms; limiting instrumental ADL


description: Evidence of cannabis dependence with intoxication with perceptual disturbance.


Stage IIA Cervical Cancer AJCC v7

description: Stage IIA includes: IIA (T2a, N0, M0); IIA1 (T2a1, N0, M0); IIA2 (T2a2, N0, M0).  T2a: Tumor without parametrial invasion.  T2a1: Clinically visible lesion 4.0 cm or less in greatest dimension.  T2a2: Clinically visible lesion more than 4.0 cm in greatest dimension.  N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 7th ed.)


Serious Adverse Event

description: Any expected or unexpected adverse event, related or unrelated to the intervention, occurring at any agent dose, any phase of product or procedure testing, that results in any of the following outcomes: death, a life-threatening adverse event, requires inpatient hospitalization (not required as part of the treatment) or prolongation of existing hospitalization, a persistent or significant disability or incapacity, or cancer, or a congenital anomaly or birth defect. Important medical events that may not result in the listed outcomes may be considered as serious when, based upon appropriate medical judgment, they represent significant hazards or potentially serious harm to the research subject or others and may require medical intervention to prevent one of the outcomes listed in this definition.


Retinoblastoma pT3c TNM Finding v8

description: Any partial-thickness involvement of the sclera within the inner two thirds. (from AJCC 8th Ed.)


Grade 2 Uterine Hemorrhage, CTCAE

description: Moderate symptoms; intervention indicated


name: Rheumatoid Arthritis without Rheumatoid Factor, Unspecified Ankle and Foot

description: Evidence of rheumatoid arthritis without rheumatoid factor in an unspecified ankle and foot.


name: Oropharyngeal (p16-Negative) Cancer cN1 TNM Finding v8

description: Oropharyngeal (p16-negative) cancer with metastasis in a single ipsilateral lymph node, 3 cm or smaller in greatest dimension and ENE (-). (from AJCC 8th Ed.)


Grade 3 Radiculitis, CTCAE

description: Severe symptoms; limiting self care ADL


Childhood Benign Liver Neoplasm

description: A childhood neoplasm that arises from the liver and is characterized by the absence of atypical or malignant cytological and architectural features, and absence of invasive features or metastatic potential.


name: Grade 5 Paranasal Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


Acantholytic Actinic Keratosis

description: Actinic keratosis characterized by the presence of acantholysis of the dysplastic keratinocytes.


name: Treatment-Related Prostate Neuroendocrine Carcinoma

description: A prostate carcinoma with partial or complete neuroendocrine differentiation that results from the transformation of castration-resistant prostate adenocarcinoma following potent androgen-deprivation therapy. The prognosis is poor.


name: Human Immunodeficiency Virus Infection Complicating Pregnancy, Third Trimester

description: Evidence of human immunodeficiency virus infection complicating pregnancy in the third trimester.


name: Pathologic Stage I Cutaneous Melanoma AJCC v8

description: Stage I includes: IA: (T1a, N0, M0); (T1b, N0, M0); IB: (T2a, N0, M0). T1a: Tumor measuring less than 0.8 mm in thickness. Ulceration status: Without ulceration. T1b: Tumor measuring less than 0.8 mm in thickness with ulceration, or 0.8-1.0 mm with or without ulceration. T2a: Tumor measuring more than 1.0 and equal to or less than 2.0 mm in thickness. Ulceration status: Without ulceration. N0: No regional lymph node metastasis detected. Presence of in-transit, satellite, and/or microsatellite metastases: No. M0: No evidence of distant metastasis. LDH level is not applicable. (AJCC 8th ed.)


name: Conjunctival Melanoma Pathologic TNM Finding v8

description: A pathologic finding about one or more characteristics of conjunctival melanoma, following the rules of the TNM AJCC v8 classification system.


Acute rheumatic pericarditis

description: Inflammation of the pericardium in acute rheumatic heart disease.


Liver Cancer TNM Finding v6

description: A finding about one or more characteristics of primary liver cancer, following the rules of the TNM AJCC v6 classification system.


name: Type 2 Diabetes Mellitus with Stable Proliferative Diabetic Retinopathy, Bilateral

description: Evidence of type 2 diabetes mellitus with stable proliferative diabetic retinopathy that is bilateral.


name: Squamous Cell Carcinoma of Unknown Primary

description: A squamous cell carcinoma which has metastasized to another anatomic site and the original site of growth has not been identified.


Primary Tumor Clinical Cancer

description: Evidence of primary tumor clinical cancer.


name: Grade 2 Proptosis and Enophthalmos, CTCAE


Malignant Abdominal Neoplasm

description: A primary or metastatic malignant neoplasm that affects the organs and structures of the abdomen.


Localized Gallbladder Carcinoma

description: A carcinoma that arises from the gallbladder and it has not spread to other anatomic sites.


name: Small Cell B-Cell Lymphoma, Lymph Nodes of Multiple Sites

description: Evidence of small cell B-cell lymphoma in the lymph nodes of multiple sites.


name: Supraglottic Cancer pT0 TNM Finding v6 and v7

description: Supraglottic cancer with no evidence of a primary tumor. (from AJCC 6th and 7th Eds.)


Glottic Cancer pT3 TNM Finding v7

description: Glottic cancer with tumor limited to the larynx with vocal cord fixation and /or invasion of paraglottic space, and/or inner cortex of the thyroid cartilage. (from AJCC 7th Ed.)


Grade 2 Papulopustular Rash, CTCAE

description: Papules and/or pustules covering 10-30% BSA, which may or may not be associated with symptoms of pruritus or tenderness; associated with psychosocial impact; limiting instrumental ADL; papules and/or pustules covering > 30% BSA with or without mild symptoms


name: Drug or Chemical Induced Diabetes Mellitus with Neurological Complication with Diabetic Polyneuropathy

description: Evidence of drug or chemical induced diabetes mellitus with neurological complication with diabetic polyneuropathy.


Bacterium-Related Malignant Neoplasm

description: A malignancy in which there is a well-documented association between a neoplastic process and a specific bacterium as the causative agent.


name: Drug or Chemical Induced Diabetes Mellitus with Neurological Complication with Diabetic Amyotrophy

description: Evidence of drug or chemical induced diabetes mellitus with neurological complication with diabetic amyotrophy.


name: Sebaceous cell carcinoma of skin of right upper eyelid, including canthus

description: Evidence of sebaceous cell carcinoma of skin of right upper eyelid including the canthus.


name: Breast Cancer pT1c TNM Finding v6 and v7

description: Breast cancer with tumor size more than 1.0 cm, but not more than 2.0 cm in greatest dimension. (from AJCC 6th and 7th Eds.)


name: Stage I Pancreatic Cancer AJCC v6 and v7

description: Stage I includes: IA (T1, N0, M0); IB (T2, N0, M0).  T1: Tumor limited to the pancreas 2 cm or less in greatest dimension.  T2: Tumor limited to the pancreas, more than 2 cm in greatest dimension.  N0: No regional lymph node metastasis.  M0: No distant metastasis. (AJCC 6th and 7th Eds.)


name: Grade 2 Urinary Tract Infection NOS with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


name: Unknown Primary Tumor pN3 TNM Finding v8

description: Unknown primary tumor with metastasis in a cervical lymph node larger than 6 cm in greatest dimension and ENE(-); or metastases in a single ipsilateral cervical lymph node larger than 3 cm in greatest dimension and ENE(+); or metastases in multiple ipsilateral, contralateral, or bilateral cervical lymph nodes, any size and ENE(+) in any node. (from AJCC 8th Ed.)


Cotton or Jute Dust Exposure

description: Environmental, occupational, or consumer-based exposure to airborne cotton or jute fibers created during the manufacture, processing, or handling of these materials.


Grade 1 Trochlear Nerve Disorder, CTCAE

description: Asymptomatic; clinical or diagnostic observations only; intervention not indicated


Less than 50 Percent Area of Interest

description: A radiographic finding indicating the area of interest is less than 50 percent.


atheroembolism of left upper extremity

description: Evidence of atheroembolism of left upper extremity.


Global Response in Viscera

description: Criteria for the response to treatment in viscera, as a component of global response.


name: Transitional cell cancer of the renal pelvis and ureter localized

description: Urothelial carcinoma of the renal pelvis or ureter that has not spread to adjacent tissues, regional lymph nodes, or distant anatomic sites.


Grade 3 Urostomy Leak, CTCAE

description: Severe symptoms; invasive intervention indicated


Disease Response in Liver

description: An assessment of the disease response to therapy within the involved liver.


name: Rheumatoid Arthritis with Rheumatoid Factor of Left Elbow without Organ or Systems Involvement

description: Evidence of rheumatoid arthritis with rheumatoid factor of left elbow without organ or systems involvement.


name: Jejunum and Ileum Neuroendocrine Tumor pM1a TNM Finding v8

description: Jejunum and ileum neuroendocrine tumor with metastasis confined to liver. (from AJCC 8th Ed.)


name: Undifferentiated Carcinoma with Osteoclast-Like Giant Cells

description: A usually aggressive malignant epithelial neoplasm composed of atypical cells which do not display evidence of glandular or squamous differentiation and giant cells resembling osteoclasts.


Non-Neoplastic Ureter Disorder

description: A non-neoplastic disorder affecting the ureter.


Grade 5 Portal Hypertension, CTCAE

description: Death


name: Major Salivary Gland Cancer pT1 TNM Finding v8

description: Major salivary gland cancer with tumor 2 cm or less in greatest dimension without extraparenchymal extension. Extraparenchymal extension is clinical or macroscopic evidence of invasion of soft tissues. Microscopic evidence alone does not constitute extraparenchymal extension for classification purposes. (from AJCC 8th Ed.)


Tumor contained within organ capsule

description: A neoplasm surrounded by a fibrous capsule.


name: Childhood Hodgkin Lymphoma by Ann Arbor Stage

description: An anatomic stage for childhood Hodgkin lymphoma based on the Ann Arbor classification criteria.


name: Diabetes Mellitus due to Underlying Condition with Mild Non-Proliferative Diabetic Retinopathy with Macular Edema, Right Eye

description: Evidence of diabetes mellitus due to underlying condition with mild non-proliferative diabetic retinopathy with macular edema in the right eye.


name: Hepatocellular Carcinoma pT0 TNM Finding v8

description: Hepatocellular carcinoma with no evidence of primary tumor. (from AJCC 8th Ed.)


name: Other vascular syndromes of brain in cerebrovascular diseases

description: Evidence of other vascular syndromes of brain in cerebrovascular diseases not specified elsewhere.


Lung Infection, CTCAE

description: A disorder characterized by an infectious process involving the lungs, including pneumonia.


name: Nasal Cavity and Ethmoid Sinus Cancer Pathologic Distant Metastasis TNM Finding v7

description: A pathologic finding about one or more characteristics of nasal cavity and ethmoid sinus cancer, following the rules of the TNM AJCC v7 classification system as they pertain to distant metastases.  There is no pathologic M0 for nasal cavity and ethmoid sinus cancer.


name: HPV-Mediated (p16-Positive) Oropharyngeal Cancer pM1 TNM Finding v8

description: HPV-mediated (p16-positive) oropharyngeal cancer with distant metastasis. (from AJCC 8th Ed.)


Poisoning by barbiturate

description: Disturbances in psychophysiological functions and responses as a result of  administration or ingestion of a member of the barbiturate class of central nervous system depressants.


Scatter Artifact

description: An artifact resulting from scatter of the beam by a dense object.


name: Grade 3 Serum Glutamic Pyruvic Transaminase, CTCAE


name: histiocytic sarcoma of central nervous system

description: Rare involvement of the central nervous system by histiocytic sarcoma.


name: Conjunctival Melanoma pT3d TNM Finding v8

description: Conjunctival melanoma with tumor of any size invading the nasolacrimal duct and/or lacrimal sac and/or paranasal sinuses. (from AJCC 8th Ed.)


Grade 2 Rectal Stenosis, CTCAE

description: Symptomatic; altered GI function


name: Grade 5 Hepatobiliary Disorders - Other, Specify, CTCAE

description: Death


name: Supraglottic Cancer Pathologic TNM Finding v7

description: A pathologic finding about one or more characteristics of supraglottic cancer, following the rules of the TNM AJCC v7 classification system.  The pathologic staging requires the use of all information obtained in clinical staging and in histologic study of the surgically resected specimens.  (from AJCC 7th Ed.)


Yeast Present

description: Confirmatory presence of yeast microorganisms.


name: Testosterone Greater than or Equal to 200 ng/dL

description: A semiquantitative finding indicating that the concentration of testosterone in a sample is greater than or equal to 200 ng/dL.


name: Biliary Tree Left Hepatic Duct Intra-Operative Injury, CTCAE


Claudication

description: Pain, cramping, and fatigue of the lower extremities upon ambulation due to ischemia.


Grade 3 Somnolence, CTCAE

description: Obtundation or stupor


name: Liver Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


name: Malignant Neoplasm of Right Renal Pelvis

description: Evidence of a malignant neoplasm of the right renal pelvis.


Pancreatic carcinoma non-resectable

description: Carcinoma of the pancreas that is not amenable to surgical removal.


Grade 2 Flatulence, CTCAE

description: Moderate; persistent; psychosocial sequelae


name: Metastatic Malignant Neoplasm in the Lacrimal Drainage System

description: A malignant neoplasm that has spread from its original site of growth to the lacrimal drainage system.


name: Other Dermatomyositis with Respiratory Involvement

description: Evidence of other dermatomyositis with respiratory involvement not specified elsewhere.


name: Nasal Cavity and Ethmoid Sinus Cancer cM1 TNM Finding v7

description: Nasal cavity and ethmoid sinus cancer with distant metastasis. (from AJCC 7th Ed.)


name: Drug or Chemical Induced Diabetes Mellitus with Neurological Complication with Diabetic Neuropathy, Unspecified

description: Evidence of drug or chemical induced diabetes mellitus with neurological complication with diabetic neuropathy.


name: TOP2A/Chromosome 17 Copy Number Ratio Finding

description: A genetic copy number finding indicating the ratio of the number of signals for a probe targeting the TOP2A gene to the number of signals for a probe targeting chromosome 17.


Metachronous Malignant Neoplasm

description: A malignant tumor that arises at a site separate from another, primary malignant tumor in the same anatomic system.  It is not clear if metachronous malignant neoplasms represent new primary tumors or metastatic disease.  Examples include metachronous osteosarcoma of the bones that develops in patients with known primary bone osteosarcoma, and metachronous Wilms' tumor that affects the opposite kidney in patients with a history of Wilms' tumor.


Peritoneal Diseases

description: A non-neoplastic or neoplastic disorder that affects the peritoneum.  Representative examples of non-neoplastic disorders include peritonitis and panniculitis.  Representative examples of neoplastic disorders include adenomatoid tumor, primary peritoneal carcinoma, metastatic carcinoma to the peritoneum, and malignant mesothelioma.


name: Soft Tissue Sarcoma of the Abdomen and Thoracic Visceral Organs cM0 TNM Finding v8

description: Soft tissue sarcoma of the abdomen and thoracic visceral organs without distant metastases. (from AJCC 8th Ed.)


name: Childhood Benign Connective and Soft Tissue Neoplasm

description: A childhood neoplasm that arises from connective and soft tissue and is characterized by the absence of atypical or malignant cytological and architectural features, and absence of invasive features or metastatic potential.


Locally Advanced Vulvar Carcinoma

description: Vulvar carcinoma that has spread to nearby tissues or lymph nodes.


Retinoblastoma pT3a TNM Finding v7

description: Retinoblastoma with tumor invading optic nerve past lamina cribrosa but not to surgical resection line or tumor exhibiting massive choroidal invasion. (from AJCC 7th Ed.)


Resectable Glioma

description: A glioma that is amenable to surgical resection.


Breast Cancer pT1 TNM Finding v6 and v7

description: Breast cancer with tumor size 2.0 cm or less in greatest dimension. (from AJCC 6th and 7th Ed.)


Vulvar Germ Cell Tumor

description: A rare germ cell tumor that arises from the vulva.


name: Chronic and other pulmonary manifestations due to radiation

description: Evidence of chronic and other pulmonary manifestations due to radiation.


Subgaleal Hemorrhage Related to Birth

description: Bleeding in the potential space between the skull periosteum and the scalp galea aponeurosis of a newborn infant due to shearing forces on the tentorium and deep venous system during labor and delivery.


name: Unspecified Atherosclerosis of Autologous Vein Bypass Graft(s) of the Extremities, Bilateral Legs

description: Evidence of unspecified atherosclerosis of autologous vein bypass graft(s) of the extremities in both legs.


High Grade Fever

description: Body temperature of 104 degrees Fahrenheit (40 degrees Celsius) or higher.


Neuroendocrine breast tumor

description: A well-differentiated neuroendocrine neoplasm that arises from the breast. It may be classified as G1 (low grade) or G2 (intermediate grade) neuroendocrine tumor.


Grade 1 Hemoglobinuria, CTCAE

description: Asymptomatic; clinical or diagnostic observations only; intervention not indicated


name: Appendiceal Carcinoma Pathologic TNM Finding v7

description: A pathologic finding about one or more characteristics of appendiceal carcinoma, following the rules of the TNM AJCC v7 classification system.  Appendiceal carcinomas are usually staged after surgical exploration of the abdomen and pathologic examination of the resected specimen.  (from AJCC 7th Ed.)


name: Ankylosing spondylitis, occipito-atlanto-axial region

description: Evidence of ankylosing spondylitis of occipito-atlanto-axial region.


Atypical Gastric Lymphoid Hyperplasia

description: An atypical lymphoid hyperplasia involving the gastric mucosa.


Childhood Low Grade Glioma

description: A low-grade glioma that occurs during childhood.


name: Post-Immunization Arthropathy, Left Knee

description: Evidence of post-immunization arthropathy in the left knee.


name: Grade 5 Oral Cavity Mucositis or Stomatitis by Clinical Examination Classification, CTCAE


name: Pleural Malignant Mesothelioma pTX TNM Finding v8

description: Pleural malignant mesothelioma in which the primary tumor cannot be assessed. (from AJCC 8th Ed.)


Grade 5 Bronchial Obstruction, CTCAE

description: Death


name: Pancreatic Neuroendocrine Tumor pT4 TNM Finding v8

description: Pancreatic neuroendocrine tumor invading adjacent organs (stomach, spleen, colon, adrenal gland) or the wall of large vessels (celiac axis or the superior mesenteric artery). (from AJCC 8th Ed.)


Grade 2 Dry Skin, CTCAE

description: Covering 10-30% BSA and associated with erythema or pruritus; limiting instrumental ADL


name: Grade 4 Hepatobiliary Disorders - Other, Specify, CTCAE

description: Life-threatening consequences; urgent intervention indicated


Unilateral Anophthalmos

description: A rare congenital abnormality characterized by the complete absence of ocular tissue in one orbit.


name: Carcinoma of the Conjunctiva TNM Finding v7

description: A finding about one or more characteristics of carcinoma of the conjunctiva, following the rules of the TNM AJCC v7 classification system.  No stage grouping is presently recommended for carcinoma of the conjunctiva.  (from AJCC 7th Ed.)


Childhood Overweight

description: A condition in which a child's body mass index (BMI) falls at or above the 85th percentile, but below the 95th percentile based on the normative values for the age and sex of the reference population.


Bone Cancer pN0 TNM Finding v7

description: Bone cancer without regional lymph node metastasis. (from AJCC 7th Ed.)


Lower GI Progression GvHD

description: An NIH lower GI score that has increased by 1 or more points, except 0 to 1.


name: Grade 1 Metabolic or Respiratory Acidosis, CTCAE


Infant Irritability, AE

description: An adverse event in a newborn characterized by crying easily and difficulty consoling.


opioid abuse with intoxication delirium

description: Evidence of opioid abuse with intoxication delirium.


name: Stage IA Esophageal Adenocarcinoma AJCC v7

description: Stage IA includes: T1, N0, M0, G1-2, X. T1: Tumor invades lamina propria, muscularis mucosae, or submucosa.  N0: No regional lymph node metastasis.  M0: No distant metastasis.  G1: Well differentiated.  G2: Moderately differentiated. GX: Grade cannot be assessed-stage grouping as G1. (AJCC 7th ed.)


name: Grade 1 Small Bowel Perforation NOS, CTCAE


name: Hepatocellular Carcinoma pT4 TNM Finding v8

description: Hepatocellular carcinoma with single tumor or multiple tumors of any size involving a major branch of the portal vein or hepatic vein, or tumor(s) with direct invasion of adjacent organs other than the gallbladder or with perforation of visceral peritoneum. (from AJCC 8th Ed.)


name: Grade 2 Sinus Infection with Unknown Absolute Neutrophil Count, CTCAE


name: Stage IV Appendix Neuroendocrine Tumor AJCC v8

description: Stage IV includes: (T1, N0, N1, M1); (T2, N0, N1, M1); (T3, N0, N1, M1); (T4, N0, N1, M1). T1: Tumor measuring 2 cm or less in greatest dimension. T2: Tumor measuring more than 2 cm but less than or equal to 4 cm. T3: Tumor measuring more than 4 cm or with subserosal invasion or involvement of the mesoappendix. T4: Tumor perforating the peritoneum or directly invading other adjacent organs or structures (excluding direct mural extension to adjacent subserosa of adjacent bowel), e.g., abdominal wall and skeletal muscle. N0: No regional lymph node metastasis. N1: Regional lymph node metastasis. M1: Distant metastasis. (AJCC 8th ed.)


Grade 1 Vaccination Complication, CTCAE

description: Mild pain; erythema 2.5-5cm; induration/swelling 2.5-5cm; does not interfere with activity


ALK Gene Rearrangement Negative

description: A genetic finding indicating that rearrangement of the ALK gene has not been detected in a sample.


name: Hypopharyngeal Cancer cN3b TNM Finding v8

description: Hypopharyngeal cancer with metastasis in any node(s) and clinically overt ENE(+). (from AJCC 8th Ed.)


name: Grade 5 Meninges Infection with Unknown Absolute Neutrophil Count, CTCAE


Vasogenic Edema

description: Edema that is characterized by increased permeability of capillary endothelial cells.


name: Grade 2 Alanine Aminotransferase Increased, CTCAE

description: >3.0-5.0 x ULN if baseline was normal; >3.0-5.0 x baseline if baseline was abnormal


Metastatic small cell carcinoma

description: A small cell neuroendocrine carcinoma that has metastasized from its original site of growth to another anatomic site.


name: Nodular Sclerosis Classic Hodgkin Lymphoma, Lymph Nodes of Head, Face, and Neck

description: Evidence of nodular sclerosis classic Hodgkin lymphoma in the lymph nodes of head, face, and neck.


MYCN Negative

description: An indication that MYCN expression has not been detected in a sample.


Fluid Absorption Alteration

description: A finding indicating a deficiency or excess in absorption of one or more fluids.


name: Grade 2 Hepatic Vein Intra-Operative Injury, CTCAE


Stevens-Johnson Syndrome, CTCAE

description: A disorder characterized by less than 10% total body skin area separation of dermis. The syndrome is thought to be a hypersensitivity complex affecting the skin and the mucous membranes.


name: T-Cell Prolymphocytic Leukemia not Having Achieved Remission

description: Evidence of T-cell prolymphocytic leukemia not having achieved remission.


Lung Cancer pM1 TNM Finding v7

description: Lung cancer with distant metastasis. (from AJCC 7th Ed.)


name: Grade 4 Cranial Nerve IX Neuropathy, CTCAE


name: Esophagus and Esophagogastric Junction Cancer pTX TNM Finding v7

description: Esophagus and esophagogastric junction cancer in which the primary tumor cannot be assessed. (from AJCC 7th Ed.)


Edema Limbs, CTCAE

description: A disorder characterized by swelling due to excessive fluid accumulation in the upper or lower extremities.


Mutation Rate

description: The frequency of mutations in a sample.


name: Other infective spondylopathies, lumbosacral region

description: Evidence of other infective spondylopathies in the lumbosacral region not specified elsewhere.


name: Grade 3 Hepatic Vein Intra-Operative Injury, CTCAE


name: Grade 2 Jejunum Intra-Operative Injury, CTCAE


Granulosa cell-theca cell tumor

description: A general term used to describe sex cord-stromal tumors characterized by the presence of granulosa cells in a thecomatous/fibrothecomatous background.


name: Grade 1 Large Bowel Mucositis or Stomatitis by Functional or Symptomatic Classification, CTCAE


Supraglottic Cancer pT4b TNM Finding v6

description: Supraglottic cancer with tumor invading prevertebral space, encasing carotid artery, or invading mediastinal structures. (from AJCC 6th Ed.)


name: Pre-Existing Hypertensive Chronic Kidney Disease Complicating Pregnancy, First Trimester

description: Evidence of pre-existing hypertensive chronic kidney disease complicating pregnancy in the first trimester.


name: Malignant Neoplasm of Axillary Tail of Left Female Breast

description: Evidence of a malignant neoplasm of the axillary tail of left female breast.


description: Evidence of subacute necrotizing myelitis of central nervous system.


name: Platinum-Resistant Fallopian Tube High Grade Serous Adenocarcinoma

description: Fallopian tube high-grade serous adenocarcinoma that progresses between one and six months of completing platinum therapy.


Non-uniform Signal Intensity Artifact

description: An artifact resulting from non-uniform signal intensities across the imaging field.


Dermal Melanoma

description: A melanoma that is confined to the dermis and subcutaneous tissue without involvement of the epidermis.


name: Grade 2 Retinal Vascular Disorder, CTCAE

description: Retinal vascular disorder without neovascularization


name: Grade 4 Foreign Body Infection with Unknown Absolute Neutrophil Count, CTCAE


Grade 1 Pharyngeal Hemorrhage, CTCAE

description: Mild symptoms; intervention not indicated


Eye Infection, CTCAE

description: A disorder characterized by an infectious process involving the eye.


name: Grade 3 Fallopian Tube Intra-Operative Injury, CTCAE


name: Gastroesophageal Junction Large Cell Neuroendocrine Carcinoma

description: An aggressive, high-grade and poorly differentiated carcinoma with neuroendocrine differentiation that arises from the gastroesophageal junction.  It is characterized by the presence of malignant large cells.


name: Merkel Cell Carcinoma pM1b TNM Finding v8

description: Merkel cell carcinoma with metastasis to lung, microscopically confirmed. (from AJCC 8th Ed.)


name: Prostate Cancer pM1c TNM Finding v6 and v7

description: Prostate cancer with metastasis to other site(s) with or without bone disease.  (from AJCC 6th and 7th Eds.)


Silent Inactivation

description: The development of asparaginase inactivity due to asparaginase antibodies in the absence of overt or recognized allergy symptoms.


Distal Bile Duct Cancer TNM Finding v8

description: A finding about one or more characteristics of distal bile duct cancer, following the rules of the TNM AJCC v8 classification system. This staging system applies to bile duct adenocarcinomas, biliary intraepithelial neoplasia, high-grade neuroendocrine carcinomas, and papillary carcinomas. Tumors arising in the ampulla of Vater, sarcomas, and well-differentiated neuroendocrine tumors (carcinoids) are not staged using this staging system. (from AJCC 8th Ed.)


name: Pancreatic Poorly Differentiated Ductal Adenocarcinoma

description: A pancreatic ductal adenocarcinoma characterized by the presence of small and irregular malignant glandular structures, solid sheets of malignant cells, and single malignant cells.


name: T-Cell Large Granular Lymphocyte Leukemia, Common Variant

description: T-cell large granular lymphocyte leukemia defined by the presence of CD3-positive, CD8-positive, and T-cell receptor alpha-beta-positive cytotoxic T-cells.


name: Atherosclerosis of Autologous Vein Bypass Graft(s) of the Extremities with Rest Pain, Left Leg

description: Evidence of atherosclerosis of autologous vein bypass graft(s) of the extremities with rest pain in the left leg.


name: Cervical Cancer Pathologic Distant Metastasis TNM Finding v9

description: A pathologic finding about one or more characteristics of cervical cancer, following the rules of the TNM AJCC v9 classification system as they pertain to distant metastases.


name: Grade 4 Anal or Perianal Infection with Unknown Absolute Neutrophil Count, CTCAE


Meningitis, CTCAE

description: A disorder characterized by acute inflammation of the meninges of the brain and/or spinal cord.


name: Grade 3 Breast Intra-Operative Injury, CTCAE


Gastric Cancer by AJCC v7 Stage

description: A term that refers to the staging of gastric carcinoma according to the American Joint Committee on Cancer, 7th edition.


Lymphocele, CTCAE

description: A disorder characterized by a cystic lesion containing lymph.


Radiculoneuropathy

description: Spontaneous degeneration of the spinal cord and peripheral nerves characterized by myelin sheath vacuolation, Wallerian degeneration and intramyelinic space infiltration by macrophages.


name: Grade 4 Bladder Infection with Unknown Absolute Neutrophil Count, CTCAE


Acute Myeloid Leukemia with del(7q)

description: Acute myeloid leukemia associated with deletion of the long arm of chromosome 7 [del(7q)].


name: Muscular Dystrophy Secondary to Mitochondrial Disorder

description: A muscular dystrophy that was caused by a primary mitochondrial disorder.


Locally Advanced Adenocarcinoma

description: Adenocarcinoma that has spread to nearby tissues or lymph nodes.


description: Evidence of acute panmyelosis with myelofibrosis not having achieved remission.


Vulvar Cancer TNM Finding v7

description: A finding about one or more characteristics of vulvar cancer, following the rules of the TNM AJCC v7 classification system.  Vulvar cancer is a surgically staged malignancy. (from AJCC 7th Ed.)


NOTCH1 Gene Mutation Negative

description: A genetic finding indicating that NOTCH1 gene mutations have not been detected in a sample.


Retinoblastoma pT3b TNM Finding v8

description: Retrolaminar invasion of the optic nerve head, not involving the transected end of the optic nerve. (from AJCC 8th Ed.)


name: Larynx Mucositis or Stomatitis by Clinical Examination Classification, CTCAE


Gallbladder Neuroendocrine Carcinoma

description: An aggressive, high-grade, and poorly differentiated carcinoma with neuroendocrine differentiation that arises from the gallbladder. The mitotic count is more than 20 per 10 HPF. It is classified as either small or large cell neuroendocrine carcinoma based on the size of the malignant cells, the prominence of the nucleoli, and the amount of cytoplasm.


Radiation Overdose

description: A higher than intended cumulative dose of radiation to a single field.


name: External Ear Infection with Unknown Absolute Neutrophil Count, CTCAE


name: Glottic Cancer pN0 TNM Finding v6 and v7

description: Glottic cancer with no metastasis to regional lymph nodes. (from AJCC 6th and 7th Eds.)


name: Colorectal Neuroendocrine Tumor pM1a TNM Finding v8

description: Colorectal neuroendocrine tumor with metastasis confined to liver. (from AJCC 8th Ed.)


Intraoperative Neurological Injury

description: Damage to any part of the nervous system during a surgical procedure.


name: Duodenum/Ampulla/Jejunum/Ileum Neuroendocrine Tumor cM0 TNM Finding v7

description: Duodenum/ampulla/jejunum/ileum neuroendocrine tumor without evidence of distant metastasis. (from AJCC 7th Ed.)


name: Grade 3 Cranial Nerve V Motor Intra-Operative Injury, CTCAE


Triple-Negative Breast Cancer Finding

description: Triple-negative breast cancer finding is a negative test result that occurs when the cells in the tumor of a breast cancer patient lack the receptors for both estrogen and progesterone and the human epidermal growth factor receptor 2.


Grade 2 Hyperthyroidism, CTCAE

description: Symptomatic; thyroid suppression therapy indicated; limiting instrumental ADL


Intermediate Bone Neoplasm

description: A locally aggressive or rarely metastasizing neoplasm that arises from the bone.


name: Nontraumatic Intracerebral Hemorrhage in Hemisphere, Subcortical

description: Evidence of nontraumatic intracerebral hemorrhage in hemisphere, subcortical.


name: Rheumatoid Arthritis of Left Wrist with Involvement of Organs and Systems

description: Evidence of rheumatoid arthritis of left wrist with involvement of organs and systems.


Regional Disease

description: A disease or condition that extends beyond the site and spreads into adjacent tissues and regional lymph nodes.


Grade 4 Injury To Carotid Artery, CTCAE

description: Life-threatening consequences; urgent intervention indicated


Grade 1 Amnesia, CTCAE

description: Mild; transient memory loss


name: Grade 5 Abdomen Infection NOS with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


name: Oropharyngeal Cancer pT4b TNM Finding v7

description: Oropharyngeal cancer with very advanced local disease.  Tumor invades lateral pterygoid muscle, pterygoid plates, lateral nasopharynx, or skull base or encases carotid artery. (from AJCC 7th Ed.)


Criminal injury

description: Trauma resulting from illegal activity.


name: Ovarian, Fallopian Tube, and Primary Peritoneal Carcinoma pT1c TNM Finding v8

description: Ovarian, fallopian tube, or primary peritoneal carcinoma with tumor limited to one or both ovaries or fallopian tubes, with any of the following: surgical spill, capsule ruptured before surgery or tumor on ovarian or fallopian tube surface, or malignant cells in ascites or peritoneal washings. (from AJCC 8th Ed.)


name: Unresectable Peritoneal Malignant Mesothelioma

description: Peritoneal malignant mesothelioma that is not amenable to surgical resection.


name: Grade 1 Anus Stricture or Stenosis, CTCAE


name: Other Psychoactive Substance Dependence with Intoxication, Unspecified

description: Evidence of other psychoactive substance dependence with intoxication not specified elsewhere.


Urethral Cancer pM1 TNM Finding v8

description: Urethral cancer with distant metastasis. (from AJCC 8th Ed.)


Hypoattenuation

description: Describes areas on an x-ray or CT scan that show up as darker than surrounding tissues.


name: Atherosclerosis of Non-Autologous Biological Bypass Graft(s) of the Left Leg with Ulceration of Calf

description: Evidence of atherosclerosis of non-autologous biological bypass graft(s) of the left leg with ulceration of calf.


name: Drug or Chemical Induced Diabetes Mellitus with Diabetic Neuropathic Arthropathy

description: Evidence of drug or chemical induced diabetes mellitus with diabetic neuropathic arthropathy.


name: Hypopharyngeal Cancer pN3a TNM Finding v8

description: Hypopharyngeal cancer with metastasis in a lymph node larger than 6 cm in greatest dimension and ENE(-). (from AJCC 8th Ed.)


Fuchs' adenoma

description: A benign proliferation of the pars plicata epithelium of the ciliary body. It is associated with aging..


Colorectal Cancer pT1 TNM Finding v8

description: Colorectal cancer with tumor invading the submucosa (through the muscularis mucosa but not into the muscularis propria). (from AJCC 8th Ed.)


Grade 2 Heart Failure, CTCAE

description: Symptoms with moderate activity or exertion


name: Grade 2 Peritoneal Cavity Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


name: Appendiceal Carcinoma cM0 TNM Finding v7

description: Appendiceal carcinoma without evidence of distant metastasis. (from AJCC 7th Ed.)


name: Adverse Event Associated with the Hepatobiliary System and Pancreas


name: Grade 2 Larynx Mucositis or Stomatitis by Clinical Examination Classification, CTCAE


name: Other Psychoactive Substance Dependence with withdrawal with Perceptual Disturbance

description: Evidence of other psychoactive substance dependence with withdrawal with perceptual disturbance not specified elsewhere.


name: Rheumatoid Heart Disease with Rheumatoid Arthritis of Left Wrist

description: Evidence of rheumatoid heart disease with rheumatoid arthritis of left wrist.


Ductal carcinoma in situ of left breast

description: Evidence of intraductal carcinoma in situ of left breast.


name: Distal Bile Duct Cancer pTX TNM Finding v7

description: Distal bile duct cancer in which the primary tumor cannot be assessed. (from AJCC 7th Ed.)


name: Type 2 Diabetes Mellitus with Proliferative Diabetic Retinopathy with Traction Retinal Detachment not Involving the Macula, Right Eye

description: Evidence of type 2 diabetes mellitus with proliferative diabetic retinopathy with traction retinal detachment not involving the macula in the right eye.


name: Leiomyosarcoma and Endometrial Stromal Sarcoma Pathologic TNM Finding v7

description: A pathologic finding about one or more characteristics of leiomyosarcoma and endometrial stromal sarcoma, following the rules of the TNM AJCC v7 classification system.


Grade 5 Enterocolitis Infectious, CTCAE

description: Death


name: Hematologic Neoplasm with Germline Predisposition

description: A term that refers to myelodysplastic syndromes, myelodysplastic/myeloproliferative neoplasms, and acute myeloid leukemias that are associated with germline mutations and are familial.


name: Grade 3 Intraoperative Endocrine Injury, CTCAE

description: Complete resection or reconstruction of injured organ/structure indicated; limiting self care ADL


name: Inhalant Dependence with Unspecified Inhalant-Induced Disorder

description: Evidence of inhalant dependence with unspecified inhalant-induced disorder.


Single Metastasis

description: One metastatic area.


Stage IIIA Vulvar Cancer AJCC v7

description: Stage IIIA includes: (T1/T2, N1a/N1b, M0); T1: Invasive vulvar cancer confined to the vulva or perineum.  T2: Vulvar cancer with tumor of any size with extension to adjacent perineal structures (lower/distal 1/3 urethra, lower/distal 1/3 vagina, anal involvement).  N1a: Vulvar cancer with one or two lymph node metastasis each measuring 5 mm or less.  N1b: Vulvar cancer with one lymph node metastasis measuring 5 mm or greater.  M0: No distant metastasis.  (AJCC 7th ed.)


Malignant Testicular Sertoli Cell Tumor

description: A Sertoli cell tumor that arises from the testis and is characterized by nuclear pleomorphism, increased mitotic activity and necrotic changes.  Metastases may be present at diagnosis.


Grade 2 Laryngeal Stenosis, CTCAE

description: Symptomatic (e.g., noisy airway breathing), no respiratory distress; medical intervention indicated (e.g., steroids); limiting instrumental ADL


name: Grade 4 External Ear Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


Recurrent Malignant Germ Cell Tumor

description: The reemergence of a malignant germ cell tumor after a period of remission.


Grade 3 Jejunal Stenosis, CTCAE

description: Severely altered GI function; tube feeding or hospitalization indicated; elective operative intervention indicated


name: Injury, Poisoning and Procedural Complications, CTCAE


Laryngeal Mucositis, CTCAE

description: A disorder characterized by ulceration or inflammation involving the mucous membrane of the larynx.


Congenital Platelets Abnormality

description: A group of rare inherited platelet disorders that involve abnormalities of platelet function or platelet production and that usually cause moderate to severe bleeding problems.


name: Cerebral Infarction due to Thrombosis of Other Cerebral Artery

description: Evidence of cerebral infarction due to a thrombosis of the other cerebral artery.


Grade 4 Hyperlipidemia, CTCAE

description: Life-threatening consequences


name: Grade 4 Eye NOS Intra-Operative Injury, CTCAE


name: Gastric Neuroendocrine Tumor cM0 TNM Finding v7

description: Gastric neuroendocrine tumor without evidence of distant metastasis. (from AJCC 7th Ed.)


name: generalized idiopathic epilepsy, not intractable, with status epilepticus

description: Evidence of generalized idiopathic epilepsy with status epilepticus that responds to treatment.


name: Papillary, Follicular, Hurthle Cell, Poorly Differentiated, and Anaplastic Thyroid Carcinoma cNX TNM Finding v8

description: Regional lymph nodes cannot be assessed. (from AJCC 8th Ed.)


name: Grade 4 Wound Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


name: Grade 5 Cranial Nerve Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


Defective Alpha Heavy Chain Present

description: An indication that cells expressing a mutated or defective form of immunoglobulin heavy chain alpha have been detected in a sample.


name: Lymphocyte-Rich Classic Hodgkin Lymphoma, Lymph Nodes of Head, Face, and Neck

description: Evidence of lymphocyte-rich classic Hodgkin lymphoma in the lymph nodes of head in the face in the and neck.


name: Direct Infection of Right Wrist in Infectious and Parasitic Diseases Classified Elsewhere

description: Evidence of direct infection of right wrist in infectious and parasitic diseases classified elsewhere.


name: Lugano Classification Childhood Hodgkin Lymphoma by AJCC v8 Stage

description: A staging system for childhood Hodgkin lymphomas based on the Lugano classification criteria. Staging for childhood Hodgkin lymphoma is the same as for the adult counterpart. (from AJCC 8th Ed.)


name: atherosclerosis of other type of bypass graft of left leg with ulceration of heel and midfoot

description: Evidence of atherosclerosis of other type of bypass graft(s) of left leg with ulceration of heel and midfoot.


name: Other Specified Diabetes Mellitus with Other Diabetic Ophthalmic Complication

description: Evidence of other specified diabetes mellitus with other diabetic ophthalmic complication not specified elsewhere.


Bladder Cancer cM0 TNM Finding v7

description: Bladder cancer without evidence of distant metastasis. (from AJCC 7th Ed.)


name: Diabetes Mellitus due to Underlying Condition with Diabetic Dermatitis

description: Evidence of diabetes mellitus due to underlying condition with diabetic dermatitis.


Hypotension, CTCAE

description: A disorder characterized by a blood pressure that is below the normal expected for an individual in a given environment.


Adult Angiosarcoma

description: An angiosarcoma occurring in the adult population.


name: Nontraumatic Subarachnoid Hemorrhage, Unspecified

description: Evidence of nontraumatic subarachnoid hemorrhage.


Grade 2 Neuralgia, CTCAE

description: Moderate pain; limiting instrumental ADL


Global Progressive Disease

description: Progressive disease in any skin, nodes, blood, or viscera category.


Adenosarcoma pTX TNM Finding v7

description: Primary tumor cannot be assessed. (from AJCC 7th Ed.)


neoplasm of optic chiasm

description: A benign or malignant neoplasm that affects the optic chiasm.


Grade 1 Pyramidal Tract Syndrome, CTCAE

description: Asymptomatic; clinical or diagnostic observations only; intervention not indicated


name: Grade 2 Respiratory Tract Hemorrhage NOS, CTCAE


Disfigurement

description: Permanent deformation of appearance.


gonococcal spondylopathy

description: Any joint disease within the vertebrae attributed to a gonococcal infection.


Abscess of pituitary

description: An inflammatory or infectious process in the pituitary gland characterized by a circumscribed, walled collection of purulent material.


Duodenal Stenosis, CTCAE

description: A disorder characterized by a narrowing of the lumen of the duodenum.


High Level of Hyaluronic Acid

description: A finding indicating high concentrations of hyaluronic acid in a sample.


name: Grade 1 Bronchus Intra-Operative Injury, CTCAE


name: Other Paralytic Syndrome following Cerebral Infarction Affecting Right Non-Dominant Side

description: Evidence of other paralytic syndrome following cerebral infarction affecting right non-dominant side not specified elsewhere.


name: Duodenum and Ampulla of Vater Neuroendocrine Tumor pM1c TNM Finding v8

description: Duodenum and ampulla of Vater neuroendocrine tumor with both hepatic and extrahepatic metastases. (from AJCC 8th Ed.)


description: Evidence of inhalant abuse with inhalant-induced dementia.


Metastatic Conjunctival Melanoma

description: Conjunctival melanoma that has spread from its original site of growth to another anatomic site.


Grade 2 Infantile Apnea, AE

description: An adverse event in a newborn characterized by apnea responsive to stimulation or intermittent fraction of inspired oxygen (FiO2) increase.


name: Appendiceal Carcinoma pN1b TNM Finding v8

description: Appendiceal carcinoma in which two to three regional lymph nodes are positive. (from AJCC 8th Ed.)


Assault by sharp object

description: A physical attack with a pointed object.


name: Grade 4 Voice Changes and Dysarthria, CTCAE


name: Localized Adult Undifferentiated High Grade Pleomorphic Sarcoma of Bone

description: An undifferentiated high grade pleomorphic sarcoma of bone that occurs in adulthood and has not spread to other anatomic sites.


name: Melanoma of the Uvea Pathologic Regional Lymph Nodes TNM Finding v7

description: A pathologic finding about one or more characteristics of melanoma of the uvea, following the rules of the TNM AJCC v7 classification system as they pertain to staging of regional lymph nodes.


Grade 1 Wound Dehiscence, CTCAE

description: Incisional separation, intervention not indicated


name: Malignant Neoplasm of Peripheral Nerves of Unspecified Upper Limb, Including Shoulder

description: Evidence of a malignant neoplasm of the peripheral nerves of unspecified upper limb including the shoulder.


Retinoblastoma cT4d TNM Finding v7

description: Intracranial extension past chiasm. (from AJCC 7th Ed.)


Iris Melanoma pT2c TNM Finding v8

description: Iris melanoma with tumor confluent with or extending into the ciliary body, choroid, or both, with secondary glaucoma. (from AJCC 8th Ed.)


name: Major Salivary Gland Cancer pN3 TNM Finding v6 and v7

description: Major salivary gland cancer with metastasis in a lymph node, more than 6 cm in greatest dimension. (from AJCC 6th and 7th Eds.)


ETV Gene Rearrangement Negative

description: A genetic finding indicating that rearrangement of ETV family genes have not been detected in a sample.


name: Grade 4 Anus Intra-Operative Injury, CTCAE


Grade 5 Hemolysis, CTCAE

description: Death


name: Pleural Malignant Mesothelioma pN0 TNM Finding v8

description: Pleural malignant mesothelioma without regional lymph node metastases. (from AJCC 8th Ed.)


Refractory Melanoma

description: Melanoma that does not respond to treatment.


name: Lugano Classification Hodgkin Lymphoma by AJCC v8 Stage

description: A staging system for Hodgkin lymphomas based on the Lugano classification criteria. Staging for childhood Hodgkin lymphoma is the same as for the adult counterpart. (from AJCC 8th Ed.)


Central Nervous System Paraganglioma

description: An extra-adrenal paraganglioma arising from the central nervous system.


Nuclear Cataract Grade 4

description: A stage of nuclear sclerotic cataract marked by severe yellowing and sclerosis of the lens nucleus. (Modified LOCS II)


Tuberculous abscess

description: An abscess resulting from infection by Mycobacterium tuberculosis.


description: An epithelioid hemangioendothelioma that has spread from its original site of growth to another anatomic site.


name: Grade 5 Artery Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


Grade 5 Hypercalcemia, CTCAE

description: Death


Papillary carcinoma in situ

description: An epithelial neoplasm with a papillary growth pattern in which the malignant cells are confined to the epithelium, without evidence of invasion.


ZRSR2 Gene Mutation Negative

description: A genetic finding indicating that ZRSR2 gene mutations have not been detected in a sample.


Glycemic Measurement Finding

description: A direct or indirect indication of the blood or plasma glucose level of a subject in order to examine their resting metabolism or analyze glycemic responses to dietary challenges or therapeutic interventions.


name: Grade 3 Larynx Obstruction and Stenosis, CTCAE


name: Grade 4 Surgical and Medical Procedures - Other, Specify, CTCAE

description: Life-threatening consequences; urgent intervention indicated


name: Lung Cancer Pathologic Distant Metastasis TNM Finding v6

description: A pathologic finding about one or more characteristics of lung cancer, following the rules of the TNM AJCC v6 classification system as they pertain to distant metastases.


Unresectable Prostate Carcinoma

description: Prostate carcinoma that is not amenable to surgical resection.


name: Fallopian Tube Cancer pT3a TNM Finding v7

description: Fallopian tube cancer with microscopic peritoneal metastasis outside the pelvis. (from AJCC 7th Ed.)


name: Grade 4 Spleen Intra-Operative Injury, CTCAE


Urethral Cancer pN2 TNM Finding v8

description: Urethral cancer with multiple regional lymph node metastasis in the inguinal region or true pelvis [perivesical, obturator, internal (hypogastric) and external iliac], or presacral lymph node. (from AJCC 8th Ed.)