name: Esophagus and Esophagogastric Junction Cancer cM1 TNM Finding v7

description: Esophagus and esophagogastric junction cancer with distant metastasis. (from AJCC 7th Ed.)


Retinoblastoma pT0 TNM Finding v8

category: biolink:PhenotypicFeature biolink:DiseaseOrPhenotypicFeature biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing

description: No evidence of intraocular tumor. (from AJCC 8th Ed.)


Grade 4 Bronchial Infection, CTCAE

description: Life-threatening consequences; urgent intervention indicated


Grade 2 Ileal Stenosis, CTCAE

description: Symptomatic; altered GI function


Bladder Cancer Clinical TNM Finding v8

description: A clinical finding about one or more characteristics of bladder cancer, following the rules of the TNM AJCC v8 classification system.


Breast Cancer pN3 TNM Finding v8

description: Breast cancer with metastases in 10 or more axillary lymph nodes; or in infraclavicular (level III axillary) lymph nodes; or positive ipsilateral internal mammary lymph nodes by imaging in the presence of one or more positive level I, II axillary lymph nodes; or in more than three axillary lymph nodes and micrometastases or macrometastases by sentinel lymph node biopsy in clinically negative ipsilateral internal mammary lymph nodes; or in ipsilateral supraclavicular lymph nodes. (from AJCC 8th Ed.)


name: Recurrent Male Reproductive System Carcinoma

category: biolink:Disease biolink:DiseaseOrPhenotypicFeature biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing

description: The reemergence of a carcinoma that affects the male reproductive system after a period of remission.


name: Grade 4 Peristomal Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


Grade 2 Corneal Infection, CTCAE

description: Localized; local intervention indicated (e.g., topical antibiotic, antifungal, or antiviral)


name: Narcolepsy in Conditions Classified Elsewhere with Cataplexy

description: Evidence of narcolepsy in conditions classified elsewhere with cataplexy.


name: Nonresorbable Material Unretrieved In Body


name: Locally Advanced Neuroendocrine Neoplasm

description: A neuroendocrine neoplasm that has spread from its original site of growth to nearby tissues or lymph nodes.


Childhood Benign Endocrine Neoplasm

description: A childhood epithelial neoplasm that arises from an endocrine organ and is characterized by the absence of atypical or malignant cytological and architectural features, and absence of invasive features or metastatic potential.


Stage IA2 Cervical Cancer AJCC v8

description: Stage IA2 includes: T1a2, Any N, M0. T1a2: Invasive cervical carcinoma with measured stromal invasion of more than 3.0 mm and not more than 5.0 mm, with a horizontal spread of 7.0 mm or less. M0: No distant metastasis. (AJCC 8th Ed.)


Grade 2 Hirsutism, CTCAE

description: In women, increase in length, thickness or density of hair in a male distribution that requires daily shaving or consistent destructive means of hair removal to camouflage; associated with psychosocial impact


name: Atherosclerosis of Non-Biological Bypass Graft(s) of the Extremities with Rest Pain, Left Leg

description: Evidence of atherosclerosis of non-biological bypass graft(s) of the extremities with rest pain in the left leg.


Intracranial Melanoma

description: A melanoma that arises from the leptomeninges within the cranium.


name: Unresectable Primary Malignant Central Nervous System Neoplasm

description: A primary malignant central nervous system neoplasm that is not amenable to surgical resection.


Grade 3 Duodenal Obstruction, CTCAE

description: Hospitalization indicated; invasive intervention indicated


name: Maxillary Sinus Cancer Pathologic Distant Metastasis TNM Finding v7

description: A pathologic finding about one or more characteristics of maxillary sinus cancer, following the rules of the TNM AJCC v7 classification system as they pertain to distant metastases.  There is no pathologic M0 for maxillary sinus cancer.


name: Grade 4 Hepatic Artery Intra-Operative Injury, CTCAE


name: Type 2 Diabetes Mellitus with Diabetic Macular Edema, Resolved following Treatment, Unspecified Eye

description: Evidence of type 2 diabetes mellitus with diabetic macular edema, resolved following treatment in an unspecified eye.


name: Chest Pain in Right Third Intercostal Space

description: The location of the chest pain is within the third intercostal space on the right side.


Adnexitis

description: Inflammation of the appendages of the uterus.


name: Grade 5 Bronchopulmonary Hemorrhage NOS, CTCAE


Injury To Jugular Vein, CTCAE

description: A finding of damage to the jugular vein.


name: Metastatic Endometrial Endometrioid Adenocarcinoma

description: An endometrial endometrioid adenocarcinoma that has spread to other anatomic sites.


name: Grade 5 Blood Infection with Unknown Absolute Neutrophil Count, CTCAE


Vulvar Cancer by AJCC v7 Stage

description: A term that refers to the staging of vulvar carcinoma according to the American Joint Committee on Cancer, 7th edition.


Genitourinary Cancer

description: A primary or metastatic malignant neoplasm that affects the genitourinary system.


COVID-19-Associated Thromboembolism

description: Thromboembolism caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).


Hemangioblastic Meningioma

description: An obsolete term referring to hemangiopericytoma of the central nervous system.


Grade 4 Dysphagia, CTCAE

description: Life-threatening consequences; urgent intervention indicated


Stage IV Gallbladder Cancer AJCC v8

description: Stage IV includes: IVA: T4, N0-1, M0; IVB: (Any T, N2, M0); (Any T, Any N, M1). T4: Tumor invading the main portal vein or hepatic artery or invading two or more extrahepatic organs or structures. N0: No regional lymph node metastasis. N1: Metastases to one to three regional lymph nodes. N2: Metastases to four or more regional lymph nodes. M0: No distant metastasis. M1: Distant metastasis. (AJCC 8th ed.)


name: Congenital hypothyroidism without goiter

description: Evidence of congenital hypothyroidism without goiter.


Recurrent Neuroendocrine Neoplasm

description: The reemergence of a neuroendocrine neoplasm after a period of remission.


name: Neuroendocrine Growth Hormone Secretion Abnormality, CTCAE


Grade 3 Depression, CTCAE

description: Severe depressive symptoms; limiting self care ADL; hospitalization not indicated


TX TNM Finding

description: A primary tumor TNM finding indicating that the status of the primary tumor cannot be assessed.


Grade 2 Laryngeal Edema, CTCAE

description: Symptomatic; medical intervention indicated (e.g., dexamethasone, epinephrine, antihistamines)


Loss of BRG1 Protein Expression

description: An immunohistochemical finding indicating negative staining of tumor cells for BRG1 protein, resulting from the mutation of the SMARCA4 gene.


name: Grade 4 Vagina Stricture or Stenosis, CTCAE


name: Other Paralytic Syndrome following Unspecified Cerebrovascular Disease Affecting Left Non-Dominant Side

description: Evidence of other paralytic syndrome following unspecified cerebrovascular disease affecting left non-dominant side not specified elsewhere.


Obesity-Related Malignant Neoplasm

description: A malignant neoplasm that occurs in the context of obesity.


name: Nasal Cavity and Paranasal Sinuses Cancer cN3 TNM Finding v8

description: Nasal cavity and paranasal sinuses cancer with metastasis in a lymph node larger than 6 cm in greatest dimension and ENE(-); or metastasis in any node(s) with clinically overt ENE(+) . (from AJCC 8th Ed.)


Arteritis Infective, CTCAE

description: A disorder characterized by an infectious process involving an artery.


Dome-Shaped Lesion

description: A lesion having the shape of a dome.


Hypopharyngeal Cancer TNM Finding v8

description: A finding about one or more characteristics of hypopharyngeal cancer, following the rules of the TNM AJCC v8 classification system. This staging system applies to all cancers of the hypopharynx. Minor salivary gland carcinomas and neuroendocrine carcinomas of the hypopharynx are included in this classification. (from AJCC 8th Ed.)


Decreased Concomitant Drug Level

description: A reduction in the level of a concomitant drug.


name: Renal Pelvis and Ureter Cancer by AJCC v7 Stage

description: A term that refers to the staging of renal pelvis and ureter cancer according to the American Joint Committee on Cancer, 7th edition.


name: Mixed Cellularity Classic Hodgkin Lymphoma, Intrathoracic Lymph Nodes

description: Evidence of mixed cellularity classic Hodgkin lymphoma, intrathoracic lymph nodes.


Grade 1 Jejunal Obstruction, CTCAE

description: Asymptomatic; clinical or diagnostic observations only; intervention not indicated


Adult Acute Basophilic Leukemia

description: An acute basophilic leukemia occurring in adults.


Glottic Cancer pT4b TNM Finding v6

description: Glottic cancer with tumor invading prevertebral space, encasing carotid artery, or invading mediastinal structures. (from AJCC 6th Ed.)


name: Grade 4 White Blood Cell Decreased, CTCAE

description: <1000/mm3; <1.0 x 10e9/L


Benign Genitourinary System Neoplasm

description: A neoplasm that arises from the genitourinary system and is characterized by the absence of atypical or malignant cytological and architectural features, and absence of invasive features or metastatic potential.


name: Grade 5 Larynx Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


Glottic Cancer pM0 TNM Finding

description: Glottic cancer with no distant metastasis. (from AJCC 6th Ed.)


name: Grade 2 Major Visceral Artery Intra-Operative Injury, CTCAE


name: Grade 5 Biliary Tree Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


X-Linked Dyskeratosis Congenita

description: Dyskeratosis congenita inherited in an X-linked recessive pattern. It is caused by mutations in the DKC1 gene.


Factor I Inactivation

description: Presence of inactivating antibodies to fibrinogen (factor I) in the blood.


name: Grade 2 Rectum Stricture or Stenosis, CTCAE


Grade 2 Injection Site Reaction, CTCAE

description: Pain; lipodystrophy; edema; phlebitis


Cannabis dependence in remission

description: Evidence of cannabis dependence, in remission.


Grade 3 Hypoalbuminemia, CTCAE

description: <2 g/dL; <20 g/L


Stage I Pancreatic Cancer AJCC v8

description: Stage I includes: IA: (T1, N0, M0); IB: (T2, N0, M0). T1: Tumor measuring 2 cm or less in greatest dimension. T2: Tumor measuring more than 2 cm and 4 cm or less in greatest dimension. N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 8th ed.)


Frotteurism

description: A disorder characterized by recurrent sexual urges, fantasies, or behaviors involving touching the genitals of or rubbing the genitals against a nonconsenting person.


name: Ampulla of Vater Cancer Pathologic TNM Finding v7

description: A pathologic finding about one or more characteristics of ampulla of Vater cancer, following the rules of the TNM AJCC v7 classification system.  The pathologic staging depends on surgical resection and pathologic examination of the specimen and associated lymph nodes. (from AJCC 7th Ed.)


Retinoblastoma pNX TNM Finding v7

description: Retinoblastoma in which the regional lymph nodes cannot be assessed.  (from AJCC 7th Ed.)


name: Grade 2 Peristomal Infection with Unknown Absolute Neutrophil Count, CTCAE


Cyst of Skene's duct

description: A rare benign lesion that arises from the vagina. It is characterized by the presence of squamous epithelial and tubular structures in a fibrovascular stroma.


Radiating Chest Pain in Lower Sternum

description: The location of the radiating chest pain is in the lower portion of the sternum.


name: Drug or Chemical Induced Diabetes Mellitus with Other Diabetic Arthropathy

description: Evidence of drug or chemical induced diabetes mellitus with other diabetic arthropathy.


name: Grade 4 Peripheral Nerve Infection with Unknown Absolute Neutrophil Count, CTCAE


name: HER2/Neu Expression by Immunohistochemistry 0

description: An immunohistochemical result of 0 for HER2/Neu expression that is considered negative for expression.


Renal and perinephric abscess

description: An abscess that is located both in the kidney and across the renal capsule into the perinephric space.


name: Grade 5 Intraoperative Gastrointestinal Injury, CTCAE

description: Death


name: Unresectable Fallopian Tube Adenocarcinoma

description: Fallopian tube adenocarcinoma that is not amenable to surgical resection.


opioid abuse with intoxication

description: Evidence of opioid abuse with intoxication.


Persistent Locoregional Disease

description: A disease that persists locally and/or regionally in regards to the site of origin despite treatment.


name: Recurrent Platinum-Sensitive Fallopian Tube Carcinoma

description: The reemergence of platinum-sensitive fallopian tube carcinoma after a period of remission.


Polycythemia Vera, Polycythemic Phase

description: Polycythemia vera characterized by the proliferation of the erythroid, granulocytic, and megakaryocytic lineages. The peripheral blood shows excess of red blood cells, neutrophilia, and thrombocytosis. The bone marrow is hypercellular for the patient's age.


name: Malignant neoplasm of pluriglandular involvement, unspecified

description: Evidence of a malignant neoplasm with pluriglandular involvement.


name: Grade 4 Gallbladder Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


Grade 3 Meningismus, CTCAE

description: Severe symptoms; limiting self care ADL


name: Adenocarcinoma in situ in tubulovillous adenoma

description: A non-invasive adenocarcinoma arising from a tubulovillous adenoma.


Leukoencephalopathy, CTCAE

description: A disorder characterized by diffuse reactive astrocytosis with multiple areas of necrotic foci without inflammation.


name: Drug or Chemical Induced Diabetes Mellitus with Mild Non-Proliferative Diabetic Retinopathy with Macular Edema, Bilateral

description: Evidence of drug or chemical induced diabetes mellitus with mild non-proliferative diabetic retinopathy with macular edema that is bilateral.


Grade 1 Neonatal Hypotension, AE

description: An adverse event in a newborn characterized by transient (less than 60 minutes), asymptomatic hypotension; not affecting perfusion; not requiring intervention.


Exceptional Response

description: An achievement of either a complete disease response, or a partial disease response of at least 6 months duration in a trial or treatment where the overall response rate is less than 10 percent.


name: Biochemical Evidence of Disease without Structural Correlate

description: An indication that biochemical markers of a disease are present but morphological markers are absent.


Cystic Trophoblastic Tumor

description: A rare trophoblastic neoplasm that arises in metastatic sites of testicular mixed germ cell tumors following chemotherapy, or is part of treated or untreated testicular mixed germ cell tumors, or is secondary to either chemotherapy-induced or spontaneous regression of testicular choriocarcinoma. It has also been described in central nervous system post-chemotherapy primary germ cell tumors. It is characterized by the presence of cysts lined by squamoid trophoblastic cells. The cysts are often compressed surrounded by other germ cell components.


Extraocular Extension

description: The spread or migration of cancer cells beyond the structures of the eye into surrounding or adjacent tissues.


name: Rheumatoid Myopathy with Rheumatoid Arthritis of Unspecified Knee

description: Evidence of rheumatoid myopathy with rheumatoid arthritis of unspecified knee.


name: Intrahepatic Bile Duct Cancer pNX TNM Finding v8

description: Intrahepatic bile duct cancer in which the regional lymph node(s) cannot be assessed.  (from AJCC 8th Ed.)


name: Parathyroid Carcinoma Pathologic TNM Finding v8

description: A pathologic finding about one or more characteristics of parathyroid carcinoma, following the rules of the TNM AJCC v8 classification system.


name: Infectious mononucleosis-like post-transplant lymphoproliferative disorder

description: An early post-transplant lymphoproliferative lesion characterized by immunoblastic proliferation and paracortical expansion as seen in infectious mononucleosis.  There is architectural preservation of the involved tissues.  Oligoclonal or monoclonal cellular populations have been detected in a small number of cases.  In some cases, a polymorphic or monomorphic post-transplant lymphoproliferative disorder may follow this early lesion.


name: Soft Tissue Sarcoma of the Head and Neck Pathologic TNM Finding v8

description: A pathologic finding about one or more characteristics of soft tissue sarcoma of the head and neck, following the rules of the TNM AJCC v8 classification system.


Viral Relapse

description: A recurrence of the same virus after a finding of aviremia at the end of planned or actual treatment.


name: Grade 4 Tracheostomy Site Bleeding, CTCAE

description: Life-threatening consequences; urgent intervention indicated


Grade 1 Dry Eye, CTCAE

description: Asymptomatic; clinical or diagnostic observations only; symptoms relieved by lubricants


name: Unspecified Malignant Neoplasm of Skin of Lip

description: Evidence of unspecified malignant neoplasm of the skin of the lip.


Recurrent Myxoid Liposarcoma

description: The reemergence of myxoid liposarcoma after a period of remission.


Sickle Cell Trait

description: An individual who is heterozygous for the mutation that causes sickle cell anemia.


name: Uterine Corpus Adenosarcoma pM1 TNM Finding v8

description: Uterine corpus adenosarcoma with distant metastasis (excluding adnexa, pelvic, and abdominal tissues). (from AJCC 8th Ed.)


name: Type 1 Diabetes Mellitus with Diabetic Macular Edema, Resolved following Treatment, Right Eye

description: Evidence of type 1 diabetes mellitus with diabetic macular edema which is resolved following treatment in the right eye.


Lung Cancer Pathologic TNM Finding v7

description: A pathologic finding about one or more characteristics of lung cancer, following the rules of the TNM AJCC v7 classification system.  The pathologic classification uses the evidence acquired before treatment, supplemented or modified by the additional evidence acquired during and after surgery, particularly from pathologic examination. (from AJCC 7th Ed.)


Stage II Gastric Cancer AJCC v6

description: Stage II includes: (T1, N2, M0), (T2a/b, N1, M0), (T3, N0, M0).  T1: Tumor invades lamina propria or submucosa. T2: Tumor invades muscularis propria or submucosa.  T2a: Tumor invades muscularis propria.  T2b: Tumor invades subserosa.  T3: Tumor penetrates serosa (visceral peritoneum) without invasion of adjacent structures. N1: Metastasis in 1 to 6 regional lymph nodes. Metastasis in 7 to 15 regional lymph nodes.  M0: No distant metastasis. (AJCC 6th ed.)


Cystic Oncocytic Neoplasm

description: An oncocytoma with cystic degenerative changes.


Grade 1 Hypertrichosis, CTCAE

description: Increase in length, thickness or density of hair that the patient is either able to camouflage by periodic shaving or removal of hairs or is not concerned enough about the overgrowth to use any form of hair removal


Decreased Drug Half Life

description: Decreased period of time required for the concentration or amount of drug in the body to be reduced to exactly one-half of a given concentration or amount.


name: Other Psychoactive Substance Dependence, in Remission

description: Evidence of other psychoactive substance dependence, in remission not specified elsewhere.


Photosensitivity, CTCAE

description: A disorder characterized by an increase in sensitivity of the skin to light.


name: Primary Mediastinal (Thymic) Large B-Cell Lymphoma, Intra-abdominal Lymph Nodes

description: Evidence of primary mediastinal (thymic) large B-cell lymphoma in the intra-abdominal lymph nodes.


name: Other Psychoactive Substance Use, Unspecified with Psychoactive Substance-Induced Psychotic Disorder with Hallucinations

description: Evidence of other psychoactive substance use, unspecified with psychoactive substance-induced psychotic disorder with hallucinations not specified elsewhere.


Unspecified Asthma, Uncomplicated

description: Evidence of unspecified asthma, uncomplicated.


Grade 2 Hypothermia, CTCAE

description: 35->32 degrees C; 95->89.6 degrees F


name: Cervix Infection with Unknown Absolute Neutrophil Count, CTCAE


Sarcoma by FNCLCC Grade

description: Grading of sarcomas according to the French Federation of Cancer Centers Sarcoma Group (FNCLCC). This sarcoma grading system is based on three factors: differentiation, mitotic count, and tumor necrosis. The scores for each factor are added to determine the grade (1 to 3) for the sarcoma.


Grade 1 Delirium, CTCAE

description: Mild acute confusional state


Compound nevus

description: A nevus composed of neoplastic melanocytes that infiltrate both the epidermis and the dermis.


name: Hodgkin's disease mixed cellularity stage I supradiaphragmatic


Unresectable Gallbladder Carcinoma

description: A carcinoma that arises from the gallbladder and it is not amenable to surgical resection.


Ectopic Decidua

description: The presence of decidual tissue outside the uterus.


Cecum Perforation, CTCAE

description: Cecum Perforation that is temporally associated with the use of a medical treatment or procedure, and that may or may not be considered related to the medical treatment or procedure.


name: Elevated Serum CA 27-29 Tumor Antigen Levels


Intraoperative Pain

description: Pain occurring during a surgical operation.


Stage IIIA Cutaneous Melanoma AJCC v7

description: Stage IIIA includes: (T1-4a, N1a, M0); (T1-4a, N2a, M0).  T1-4a: Non-ulcerated cutaneous melanoma of any thickness.  N1a: Cutaneous melanoma with micrometastasis in one regional lymph node.  N2a: Cutaneous melanoma with micrometastases in 2-3 regional lymph nodes.  M0: No detectable evidence of distant metastases. (from AJCC 7th Ed.)


name: Sustained Ventricular Arrhythmia Related to COVID-19

description: Ventricular tachycardia or ventricular fibrillation lasting greater than or equal to 30 seconds, or requiring direct current cardioversion (DCCV) in a patient with probable or confirmed acute COVID-19.


SWI/SNF Complex Deficiency

description: A finding indicating the loss or inactivation of an SWI/SNF complex subunit.


name: Breast Columnar Cell Hyperplasia with Atypia

description: A columnar cell lesion characterized by the presence of enlarged terminal ductal lobular units with dilated acini.  The acini are lined by more than two layers of columnar epithelial cells.  Cytologic atypia is present.  Prominent apical cytoplasmic snouts and intraluminal secretions are also present.


name: Grade 3 Cervix Intra-Operative Injury, CTCAE


Grade 5 Chronic Kidney Disease, CTCAE

description: Death


Nail Changes, CTCAE 5.0

description: A disorder characterized by a change in the nails.


Resectable Liposarcoma

description: Liposarcoma that is amenable to surgical resection.


Cutaneous Melanoma pN1a TNM Finding v8

description: Cutaneous melanoma with one clinically occult nodal metastasis (i.e., detected by sentinel lymph node biopsy). Presence of in-transit, satellite, and/or microsatellite metastases: No.  (from AJCC 8th Ed.)


Stage IIIC Testicular Cancer AJCC v8

description: Stage IIIC includes: (Any pT/TX, N1-3, M0, S3); (Any pT/TX, Any N, M1a, S3); (Any pT/TX, Any N, M1b, Any S). TX: Testicular cancer in which the primary tumor cannot be assessed. N1: Testicular cancer with metastasis with a lymph node mass 2 cm or smaller in greatest dimension and less than or equal to five nodes positive, none larger than 2 cm in greatest dimension. N2: Testicular cancer with metastasis with a lymph node mass larger than 2 cm but not larger than 5 cm in greatest dimension; or more than five nodes positive, none larger than 5 cm; or evidence of extranodal extension of tumor. N3: Testicular cancer with metastasis with a lymph node mass larger than 5 cm in greatest dimension. M0: Testicular cancer without evidence of distant metastasis. M1a: Testicular cancer with non-retroperitoneal nodal or pulmonary metastases. M1b: Testicular cancer with non-pulmonary visceral metastases. S3: LDH more than 10 x N or hCG (mlU/mL) more than 50,000 or AFP (ng/mL) more than 10,000. N indicates the upper limit of normal for the LDH assay. (AJCC 8th ed.)


name: Recurrent Adult Acute Lymphoblastic Leukemia

description: The reemergence of acute lymphoblastic leukemia in adults after a period of remission.


False Positive

description: A test result that shows evidence of a result or condition although it is not actually present.


Grade 3 Hypophysitis, CTCAE

description: Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL


name: Grade 5 Cranial Nerve V Neuropathy, CTCAE


Biliary Intraepithelial Neoplasia-1

description: Biliary intraepithelial neoplasia characterized by the presence of low grade epithelial atypia.


name: Grade 4 Joint Intra-Operative Injury, CTCAE


Grade 4 Ileal Perforation, CTCAE

description: Life-threatening consequences; urgent operative intervention indicated


Malignant Neoplasm of Right Cornea

description: Evidence of a malignant neoplasm of the right cornea.


name: Melanoma in situ of lower limb, including hip

description: Evidence of melanoma in situ of lower limb including the hip.


name: Grade 2 Cranial Nerve XI Intra-Operative Injury, CTCAE


name: Primary Graft Failure After Hematopoietic Cell Transplantation

description: Failure of initial engraftment of donor hematopoietic cells.


Refractory Aggressive NK-Cell Leukemia

description: Aggressive NK-cell leukemia that is resistant to treatment.


Grade 2 Malaise, CTCAE

description: Uneasiness or lack of well being limiting instrumental ADL


Grade 3 Spinal Fracture, CTCAE

description: Severe back pain; hospitalization or intervention indicated for pain control (e.g., vertebroplasty); limiting self care ADL; disability


name: Grade 1 Extrapyramidal and Involuntary Movement and Restlessness, CTCAE


Grade 5 Peritoneal Necrosis, CTCAE

description: Death


Cystitis Noninfective, CTCAE

description: A disorder characterized by inflammation of the bladder which is not caused by an infection of the urinary tract.


name: Perihilar Bile Duct Cancer cM1 TNM Finding v8

description: Perihilar bile duct cancer with distant metastasis. (from AJCC 8th Ed.)


name: Grade 5 Intraoperative Splenic Injury, CTCAE

description: Death


Factor VIII Inactivation

description: Presence of inactivating antibodies to factor VIII in the blood.


Peritoneal Necrosis, CTCAE

description: A disorder characterized by a necrotic process occurring in the peritoneum.


name: Monoplegia of Lower Limb following Other Cerebrovascular Disease Affecting Left Non-Dominant Side

description: Evidence of monoplegia of lower limb following other cerebrovascular disease affecting left non-dominant side.


name: Grade 3 Foreign Body Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


name: Grade 2 Upper Respiratory Infection, CTCAE

description: Moderate symptoms; oral intervention indicated (e.g., antibiotic, antifungal, or antiviral)


name: Hallucinogen Use, Unspecified with Hallucinogen-Induced Psychotic Disorder with Hallucinations

description: Evidence of hallucinogen use, unspecified with hallucinogen-induced psychotic disorder with hallucinations.


Adrenal Cancer pTX TNM Finding v7

description: Adrenal cancer in which the primary tumor cannot be assessed. (from AJCC 7th Ed.)


name: Ocular Adnexal Lymphoma pT4 TNM Finding v8

description: Orbital adnexal lymphoma and extraorbital lymphoma extending beyond the orbit to adjacent structures, such as bone, maxillofacial sinuses, and brain. (from AJCC 8th Ed.)


Chest Pain in Sternum

description: The location of the chest pain is in the middle of the anterior wall of the thorax, bounded by the clavicles, above, and with the cartilages of the first seven ribs, along the sides.


name: Ocular Adnexal Lymphoma pT1a TNM Finding v7

description: Bulbar conjunctiva only. (from AJCC 7th Ed.)


Other Stimulant Abuse, Uncomplicated

description: Evidence of other stimulant abuse, uncomplicated not specified elsewhere.


name: Esophagus and Esophagogastric Junction Cancer Clinical TNM Finding v7

description: A clinical finding about one or more characteristics of esophagus and esophagogastric junction cancer, following the rules of the TNM AJCC v7 classification system.  Clinical classification is based on evidence before primary treatment.  It involves esophagoscopy with biopsy, endoscopic esophageal ultrasound (EUS), EUS-directed fine-needle aspiration (EUS-FNA), fused computed tomography (CT), PET/CT for assessment of T, N, M, and G classifications, and histopathologic type.  Clinical reclassification during or following chemotherapy and/or radiotherapy is designated by the prefix yc.  (from AJCC 7th Ed.)


Scrotal Infection

description: A bacterial, fungal or viral infectious process affecting the scrotum.


name: Leiomyosarcoma and Endometrial Stromal Sarcoma Clinical TNM Finding v7

description: A clinical finding about one or more characteristics of leiomyosarcoma and endometrial stromal sarcoma, following the rules of the TNM AJCC v7 classification system.


Tubular adenoma of breast

description: A benign, well circumscribed neoplasm that arises from the breast.  It is composed entirely of tubular structures that contain epithelial and myoepithelial cells.


Laryngeal Cancer pN2c TNM Finding v8

description: Laryngeal cancer with metastasis in bilateral or contralateral lymph nodes, none more than 6 cm in greatest dimension and ENE(-). (from AJCC 8th Ed.)


name: Type 2 diabetes mellitus with hyperosmolarity with coma

description: Evidence of type 2 diabetes mellitus with hyperosmolarity with coma.


name: Unspecified Atherosclerosis of Autologous Vein Bypass Graft(s) of the Extremities, Right Leg

description: Evidence of unspecified atherosclerosis of autologous vein bypass graft(s) of the extremities in the right leg.


Stage IVA Gallbladder Cancer AJCC v7

description: Stage IVA includes: T4, N0-1, M0. T4: Tumor invades the main portal vein or hepatic artery, or invades two or more extrahepatic organs or structures.  N0: No regional lymph node metastasis.  N1: Metastases to nodes along the cystic duct, common bile duct, hepatic artery, and/or portal vein. M0: No distant metastasis.  (from AJCC 7th Ed.)


Ocular surface squamous neoplasia

description: An umbrella term that comprises the spectrum of squamous neoplasms of the conjunctiva, ranging  from low-grade squamous intraepithelial neoplasia to invasive conjunctival squamous cell carcinoma.


BAP1 Negative

description: An indication that expression of BAP1 has not been detected in a sample.


name: Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma, Unspecified, Intra-abdominal Lymph Nodes

description: Evidence of an unspecified mature T-cell and NK-cell non-Hodgkin lymphoma in the intra-abdominal lymph nodes.


Grade 4 Rectal Stenosis, CTCAE

description: Life-threatening consequences; urgent operative intervention indicated


Urethritis Cystica and Glandularis

description: A reactive inflammatory disorder affecting the urethra.  It is characterized by the development of small cysts in the urethral wall.  The cysts are lined by urothelial cells and metaplastic glandular cells.


Grade 1 Skin Hypopigmentation, CTCAE

description: Hypopigmentation or depigmentation covering <10% BSA; no psychosocial impact


Androgen Receptor Status

description: Refers to the presence or absence of androgen receptor molecules on the surface of the cells in a specimen.


name: Grade 5 Wound Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


name: Grade 3 Outer Ear Pinna Intra-Operative Injury, CTCAE


name: Intraocular Malignant Peripheral Nerve Sheath Tumor

description: A malignant peripheral nerve sheath tumor that occurs in the intraocular area.


name: Congenital spondylolysis of lumbosacral region

description: A defect in the pars interarticularis of the vertebral arch of a lumbar or sacral vertebra that is present at the time of birth.


name: Malignant Neoplasm of Lower-Outer Quadrant of Unspecified Male Breast

description: Evidence of a malignant neoplasm of the lower-outer quadrant of unspecified male breast.


name: Grade 1 Bronchospasm and Wheezing, CTCAE


Chronic Phase Primary Myelofibrosis

description: Primary myelofibrosis characterized by the presence of less than 10% blasts in the peripheral blood or bone marrow.


Advanced NUT Carcinoma

description: NUT carcinoma that has spread extensively to other anatomic sites or is no longer responding to treatment.


Rapid Early Response

description: An evaluation prior to the completion of therapy that the individual is responding rapidly to therapy.


Immature Granulocytic Sarcoma

description: A granulocytic sarcoma composed of myeloblasts and promyelocytes (WHO 2001).


Foreign body in genitourinary tract

description: Extraneous material located within the genital and urinary organs.


name: Bladder Cancer pTX TNM Finding v6 and v7

description: Bladder cancer in which the primary tumor cannot be assessed. (from AJCC 6th and 7th Eds.)


Staphylococcal osteomyelitis

description: Osteomyelitis resulting from an infection with Staphylococcus.


name: Other Malignant Neoplasm Skin of Unspecified Ear and External Auricular Canal

description: Evidence of other malignant neoplasm skin of unspecified ear and external auricular canal not specified elsewhere.


Non-Neoplastic Lacrimal System Disorder

description: A non-neoplastic disorder that affects the lacrimal gland and/or the lacrimal drainage system.


Neonatal Rash, AE

description: An adverse event in a newborn characterized by an eruption in the skin which affects its appearance and/or texture.


Unresectable Fallopian Tube Carcinoma

description: Fallopian tube carcinoma that is not amenable to surgical resection.


Grade 4 Iron Overload, CTCAE

description: Life-threatening consequences; urgent intervention indicated


Mismatch Repair Proficient

description: A finding indicating that a sample has normal concentrations of unmutated mismatch repair proteins and is either microsatellite stable or has low microsatellite instability.


name: Grade 5 Salivary Gland Infection with Unknown Absolute Neutrophil Count, CTCAE


name: Grade 2 Left Ventricular Systolic Dysfunction, CTCAE


name: Chronic Peptic Ulcer, Site Unspecified, without Hemorrhage or Perforation

description: Evidence of chronic peptic ulcer, site unspecified, without hemorrhage or perforation.


Cooking-Related Smoke Exposure

description: Environmental, occupational or consumer-based exposure to vaporized materials produced when food products are being cooked.


Felty's syndrome, multiple sites

description: Evidence of Felty's syndrome in multiple sites.


Grade 1 Hepatitis Viral, CTCAE

description: Asymptomatic, intervention not indicated


Vaginal Cancer Clinical TNM Finding v7

description: A clinical finding about one or more characteristics of vaginal cancer, following the rules of the TNM AJCC v7 classification system.


name: Rheumatoid Vasculitis with Rheumatoid Arthritis of Left Shoulder

description: Evidence of rheumatoid vasculitis with rheumatoid arthritis of left shoulder.


Childhood Sarcoma

description: A sarcoma that occurs during childhood.


description: Evidence of rheumatoid lung disease with rheumatoid arthritis of multiple sites.


name: Other Psychoactive Substance Abuse with Psychoactive Substance-Induced Psychotic Disorder, Unspecified

description: Evidence of other psychoactive substance abuse with psychoactive substance-induced psychotic disorder not specified elsewhere.


name: Grade 3 Bronchus Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


Locally Advanced Anal Carcinoma

description: Anal carcinoma that has spread to nearby tissues or lymph nodes.


name: Synchronous Nodules without Dominant Lesion(s)

description: A finding of multiple pulmonary nodules in which radiologic imaging shows no evidence of a dominant lesion.


name: Grade 1 Lung Intra-Operative Injury, CTCAE


Laryngeal Cancer pN2 TNM Finding v8

description: Laryngeal cancer with metastasis in a single ipsilateral lymph node, 3 cm or less in greatest dimension and ENE(+); or metastasis in a single ipsilateral lymph node, more than 3 cm but not more than 6 cm in greatest dimension and ENE(-); or metastases in multiple ipsilateral lymph nodes, none more than 6 cm in greatest dimension and ENE(-); or metastasis in bilateral or contralateral lymph nodes, none more than 6 cm in greatest dimension and ENE(-). (from AJCC 8th Ed.)


Rectal Fistula, CTCAE

description: A disorder characterized by an abnormal communication between the rectum and another organ or anatomic site.


Small Intestine Infection, CTCAE

description: A disorder characterized by an infectious process involving the small intestine.


name: Mental disorder due to a general medical condition

description: A category of psychiatric disorders which are the direct physiologic consequence of a general medical condition.


name: Non-Rheumatic Aortic Valve Insufficiency

description: Evidence of non-rheumatic aortic valve insufficiency.


Necrotising vasculopathy

description: Disorders of blood vessels characterized by luminal narrowing due to intramural immune deposits.


name: Spinal enthesopathy of cervicothoracic region

description: Evidence of spinal enthesopathy in the cervicothoracic region.


Liver Dysplastic Nodule

description: A premalignant neoplastic nodular lesion of the liver that usually measures less than 15 mm.  It is found during microscopic examination of liver tissues, usually in cirrhotic livers.  Based on the degree of atypia, it is classified as low or high grade.


Grade 4 Ascites, CTCAE

description: Life-threatening consequences; urgent operative intervention indicated


name: Pathologic Stage III Retinoblastoma AJCC v8

description: Stage III includes: Any pT, pN1, cM0, Any H. pN1: Regional lymph node involvement. cM0: No signs or symptoms of intracranial or distant metastasis. HX: Unknown or insufficient evidence of a constitutional RB1 gene mutation. H0: Normal RB1 alleles in blood tested with demonstrated high-sensitivity assays. H1: Bilateral retinoblastoma, retinoblastoma with an intracranial primitive neuroectodermal tumor (i.e., trilateral retinoblastoma), patient with family history of retinoblastoma, or molecular definition of a constitutional RB1 gene mutation. (AJCC 8th ed.)


Grade 2 Uterine Anastomotic Leak, CTCAE

description: Symptomatic; medical intervention indicated


Other myeloid leukemia, in remission

description: Evidence of other myeloid leukemia in remission not specified elsewhere.


name: Grade 5 Cranial Nerve XII Neuropathy, CTCAE


name: Metastatic Platinum-Resistant Fallopian Tube Carcinoma

description: A platinum-resistant fallopian tube carcinoma that has spread from its original site of growth to another anatomic site.


name: diabetes mellitus type 1 with hypoglycemia without coma

description: Evidence of type 1 diabetes mellitus with hypoglycemia without coma.


Grade 1 Vaginal Infection, CTCAE

description: Localized, local intervention indicated


name: Grade 4 Injury To Superior Vena Cava, CTCAE

description: Life-threatening consequences; urgent intervention indicated


name: Major Salivary Gland Cancer cM1 TNM Finding v7

description: Major salivary gland cancer with distant metastasis. (from AJCC 7th Ed.)


Stage I Uterine Corpus Cancer

description: Stage I includes: I (T1, N0, M0); IA: (T1a, N0, M0); IB (T1b, N0, M0). T1: Tumor confined to corpus uteri. T1a: Tumor limited to the endometrium or invades less than one-half of the myometrium. T1b: Tumor invades one-half or more of the myometrium. N0: No regional lymph node metastasis. M0: No distant metastasis. This staging applies to carcinomas and carcinosarcomas. (AJCC 7th ed.)


Central Nervous System Dermoid Cyst

description: A dermoid cyst arising in the central nervous system.


name: Grade 2 Small Bowel Mucositis or Stomatitis by Functional or Symptomatic Classification, CTCAE


name: Nasopharyngeal Cancer cM0 TNM Finding v8

description: Nasopharyngeal cancer without evidence of distant metastasis. (from AJCC 8th Ed.)


name: Drug or Chemical Induced Diabetes Mellitus with Moderate Non-Proliferative Diabetic Retinopathy without Macular Edema, Left Eye

description: Evidence of drug or chemical induced diabetes mellitus with moderate non-proliferative diabetic retinopathy without macular edema in the left eye.


T4b TNM Finding

description: A general term that refers to a TNM finding of a primary tumor with direct invasion of adjacent structures. The definition of T4b TNM finding depends on the specific type of cancer that it refers to; for example, for bladder cancer it refers to a primary tumor that invades the pelvic wall and abdominal wall; for gastric cancer it refers to a primary tumor that invades adjacent structures; for colorectal cancer it refers to a primary tumor with direct invasion or adherence to other organs or structures.


name: Grade 2 Intraoperative Urinary Injury, CTCAE

description: Partial resection of injured organ/structure indicated


Mild Chronic Inflammation

description: A chronic inflammatory process characterized by the accumulation of a small number of lymphocytes and plasma cells.


MX TNM Finding

description: A distant metastasis TNM finding indicating that the status of distant metastasis cannot be assessed.


Hypernatremia, CTCAE

description: A disorder characterized by laboratory test results that indicate an elevation in the concentration of sodium in the blood.


name: Grade 1 Aspartate Aminotransferase Increased, CTCAE

description: >ULN-3.0 x ULN if baseline was normal; 1.5-3.0 x baseline if baseline was abnormal


name: Ocular Adnexal Lymphoma Pathologic Distant Metastasis TNM Finding v8

description: A pathologic finding about one or more characteristics of ocular adnexal lymphoma, following the rules of the TNM AJCC v8 classification system as they pertain to distant metastases.


name: Intrahepatic Bile Duct Cancer pN1 TNM Finding v8

description: Intrahepatic bile duct cancer with regional lymph node metastasis. (from AJCC 8th Ed.)


name: Other Stimulant Abuse with Stimulant-Induced Anxiety Disorder

description: Evidence of other stimulant abuse with stimulant-induced anxiety disorder not specified elsewhere.


name: Intrahepatic Bile Duct Cancer cM1 TNM Finding v8

description: Intrahepatic bile duct cancer with distant metastasis. (from AJCC 8th Ed.)


Traumatic arthropathy

description: Any arthropathy that is caused by trauma.


name: Appendiceal Carcinoma Pathologic Distant Metastasis TNM Finding v8

description: A pathologic finding about one or more characteristics of appendiceal carcinoma, following the rules of the TNM AJCC v8 classification system as they pertain to distant metastases.


name: Monoplegia of Lower Limb following Unspecified Cerebrovascular Disease Affecting Left Dominant Side

description: Evidence of monoplegia of lower limb following unspecified cerebrovascular disease affecting left dominant side.


name: Direct Infection of Left Hand in Infectious and Parasitic Diseases Classified Elsewhere

description: Evidence of direct infection of left hand in infectious and parasitic diseases classified elsewhere.


Other specified nutritional anemias

description: Evidence of other specified nutritional anemias not specified elsewhere.


name: Grade 5 Blood and Lymphatic System Disorders - Other, Specify, CTCAE

description: Death


name: Locally Advanced Pancreatic Adenocarcinoma

description: A pancreatic adenocarcinoma that has spread from its original site of growth to nearby tissues or lymph nodes.


name: Renal Pelvis and Ureter Cancer cM1 TNM Finding v8

description: Renal pelvis and ureter cancer with distant metastasis. (from AJCC 8th Ed.)


name: Adverse Event Associated with Secondary Malignancy


Ileal Perforation, CTCAE 5.0

description: A disorder characterized by a rupture in the ileal wall.


name: Pancreatic Duct Intra-Operative Injury, CTCAE


Grade 2 Vitreous Hemorrhage, CTCAE

description: Symptomatic; moderate decrease in visual acuity (best corrected visual acuity 20/40 and better or 3 lines or less decreased vision from known baseline); limiting instrumental ADL


Laryngeal Carcinoid Tumor

description: A rare, well differentiated, low grade neuroendocrine neoplasm that arises from the larynx.


name: Grade 5 Skin Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


name: Grade 3 Anal Sphincter Intra-Operative Injury, CTCAE


name: Drug or Chemical Induced Diabetes Mellitus with Severe Non-Proliferative Diabetic Retinopathy with Macular Edema

description: Evidence of drug or chemical induced diabetes mellitus with severe non-proliferative diabetic retinopathy with macular edema.


Adenosarcoma pT4 TNM Finding v7

description: Tumor invades bladder or rectum. (from AJCC 7th Ed.)


name: Type 1 Diabetes Mellitus with Proliferative Diabetic Retinopathy with Traction Retinal Detachment not Involving the Macula, Unspecified Eye

description: Evidence of type 1 diabetes mellitus with proliferative diabetic retinopathy with traction retinal detachment not involving the macula in an unspecified eye.


Reiter's Disease, Unspecified Wrist

description: Evidence of Reiter's disease in an unspecified wrist.


Grade 1 Sleep Apnea, CTCAE

description: Snoring and nocturnal sleep arousal without apneic periods


Neonatal Lesion

description: A benign or malignant lesion that occurs in the neonatal period.


name: Grade 4 Face NOS Intra-Operative Injury, CTCAE


name: Grade 2 Hearing Patients without Baseline Audiogram and Not Enrolled in a Monitoring Program, CTCAE


name: Grade 4 Urethra Infection with Unknown Absolute Neutrophil Count, CTCAE


Skin Ulceration, CTCAE

description: A disorder characterized by a circumscribed, erosive lesion on the skin.


name: Grade 2 External Ear Infection with Unknown Absolute Neutrophil Count, CTCAE


name: Pre-Existing Secondary Hypertension Complicating Pregnancy, Third Trimester

description: Evidence of pre-existing secondary hypertension complicating pregnancy in the third trimester.


name: Opioid Use, Unspecified with Opioid-Induced Psychotic Disorder with Delusions

description: Evidence of opioid use, unspecified with opioid-induced psychotic disorder with delusions.


Advanced Neuroendocrine Neoplasm

description: A neuroendocrine neoplasm that has spread extensively to other anatomic sites or is no longer responding to treatment.


name: Systemic Mastocytosis with an Associated Germ Cell Tumor

description: A disorder characterized by systemic infiltration of internal organs by aggregates of neoplastic mast cells and the presence of a co-occurring germ cell tumor.


name: Grade 4 Stomach Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


Excrescence

description: An abnormal outgrowth.


Abnormal Urine Test Result

description: A laboratory test result indicating a finding outside the parameters of normal urine measurements.


name: Stage IV Testicular Non-Seminomatous Germ Cell Tumor


Grade 2 Skin Induration, CTCAE

description: Moderate induration, able to slide skin, unable to pinch skin; limiting instrumental ADL


Mesonephric-like adenocarcinoma

description: An exceedingly rare adenocarcinoma that arises from the uterine corpus and ovary and displays mesonephric differentiation. Some tumors are thought to derive from mesonephric duct (Wolffian duct) remnants. Others may have a Mullerian duct lineage.


Adult Acute Megakaryoblastic Leukemia

description: An acute megakaryoblastic leukemia occurring in adults.


name: Cognitive Deficits following Unspecified Cerebrovascular Disease

description: Evidence of cognitive deficits following unspecified cerebrovascular disease.


Treatment-sensitive HIV Infection

description: An infection with human immunodeficiency virus that responds to therapy.


name: Atherosclerosis of Other Type of Bypass Graft(s) of the Extremities with Intermittent Claudication, Bilateral Legs

description: Evidence of atherosclerosis of other type of bypass graft(s) of the extremities with intermittent claudication in both legs.


name: Jejunum and Ileum Neuroendocrine Tumor Pathologic TNM Finding v8

description: A pathologic finding about one or more characteristics of a jejunum and ileum neuroendocrine tumor, following the rules of the TNM AJCC v8 classification system.


Acute Myeloid Leukemia with del(20q)

description: Acute myeloid leukemia associated with deletion of the long arm of chromosome 20 [del(20q)].


Deep penetrating nevus

description: A subtype of WNT-activated deep penetrating/plexiform melanocytoma (nevus). It is characterized by a wedge-shaped pattern and extension of the neoplastic melanocytic proliferation into the deep reticular dermis or subcutis.


name: Allergic Rhinitis Including Sneezing Nasal Stuffiness Postnasal Drip, CTCAE


Ecchordosis physaliphora

description: A very rare, slow growing, usually asymptomatic hamartomatous lesion that arises from ectopic notochordal tissue.  Morphologically it is characterized by the presence of typical physaliphorous cells in a myxoid background.


neoplasm of basal ganglia

description: A benign or malignant neoplasm that affects the basal ganglia.


TNFSF9 Gene Mutation Negative

description: A genetic finding indicating that TNFSF9 gene mutations have not been detected in a sample.


Grade 1 Atelectasis, CTCAE

description: Asymptomatic; clinical or diagnostic observations only; intervention not indicated


Hyperlactemia

description: Abnormally high level of lactate in the blood.


name: Hemiplegia following Cerebral Infarction Affecting Left Dominant Side

description: Evidence of hemiplegia following cerebral infarction affecting left dominant side.


description: Coagulation disorder caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).


Cavernous Angioleiomyoma

description: A morphologic variant of angioleiomyoma characterized by the presence of markedly dilated vascular channels.


Peri-prosthetic Joint Infection

description: Infection around an implant following joint replacement.


name: Type 2 Diabetes Mellitus with Proliferative Diabetic Retinopathy with Traction Retinal Detachment Involving the Macula, Left Eye

description: Evidence of type 2 diabetes mellitus with proliferative diabetic retinopathy with traction retinal detachment involving the macula in the left eye.


name: Grade 3 Urinary Conduit Intra-Operative Injury, CTCAE


name: Grade 1 Persistent Pulmonary Hypertension of the Newborn, AE

description: An adverse event in a newborn characterized by technical evidence of increased right ventricular pressures; no clinical symptoms.


name: Adverse Event Associated with the Kidney and Genitourinary System


name: Grade 2 Abdominal Distension or Bloating, CTCAE


name: Grade 2 Nails Intra-Operative Injury, CTCAE


Renal Calculi, CTCAE

description: A disorder characterized by the formation of crystals/kidney stones in the pelvis of the kidney.


name: Other Iatrogenic Immunodeficiency-Related Lymphoproliferative Disorders

description: Lymphoid proliferations or lymphomas that arise in patients treated with immunosuppressive drugs for autoimmune diseases or conditions other than in the post-transplant setting. (WHO 2017)


Grade 3 Testicular Pain, CTCAE

description: Severe pain; limiting self care ADL


name: Gastric Neuroendocrine Tumor pN1 TNM Finding v7

description: Gastric neuroendocrine tumor with regional lymph node metastasis. (from AJCC 7th Ed.)


name: Grade 1 Neuralgia and Peripheral Nerve Pain, CTCAE


adenocarcinoma of urinary tract

description: A rare carcinoma with pure glandular differentiation arising anywhere in the urinary tract. This group does not include clear cell and endometrioid adenocarcinomas.


Occlusion

description: Obstruction or a closure of hollow organ, passageway or vessel; also the transient approximation of the edges of a natural opening; imperforation.


name: Metastatic Childhood Ependymoma by Toronto Guidelines v2

description: Disease beyond local site (e.g., other lesions in brain or spine or tumor cells in CSF or distant metastases). (Childhood cancer staging for population registries according to the Toronto Childhood Cancer Stage Guidelines - Version 2. Cancer Council Queensland and Cancer Australia: Brisbane, Australia; 2021.)


name: Insulin-dependent diabetes mellitus with other specified complications

description: Evidence of type 1 diabetes mellitus with other specified complication.


Bacterial gastroenteritis

description: Gastroenteritis resulting from a bacterial infection.


Clinical Course of Disease

description: A term that refers to the nature and/or clinical outcome of a disease (e.g., acute or chronic disease, aggressive or indolent disease, recurrent disease, etc.).


Pure Ground Glass Nodule

description: Focal increased opacity through which normal parenchymal structures (airways and vessels) can be seen. If, on lung windows, there is a solid component of greater than or equal to 2 mm that is not vascular or airway, the nodule is not pure ground glass.  Visibility of normal underlying interstitium is acceptable.


Grade 1 Pulmonary Edema, CTCAE

description: Radiologic findings only; minimal dyspnea on exertion


name: Oropharyngeal (p16-Negative) Cancer Clinical TNM Finding v8

description: A clinical finding about one or more characteristics of p16-negative oropharyngeal cancer, following the rules of the TNM AJCC v8 classification system.


Adrenal Cancer pNX TNM Finding v7

description: Adrenal cancer in which the regional lymph nodes cannot be assessed.  (from AJCC 7th Ed.)


Foregut Neuroendocrine Tumor G3

description: A neuroendocrine tumor grade 3 that arises from the esophagus, stomach, or duodenum.


Grade 3 Creatinine Increased, CTCAE

description: >3.0 x baseline; >3.0-6.0 x ULN


name: Diabetes Mellitus due to Underlying Condition with Proliferative Diabetic Retinopathy with Macular Edema, Bilateral

description: Evidence of diabetes mellitus due to underlying condition with proliferative diabetic retinopathy with macular edema that is bilateral.


Non-serious Adverse Event

description: Any adverse experience that does not meet the definition of serious. Non-serious adverse events are classified as mild, moderate and severe.


White Matter Injury

description: Focal areas of necrosis, with or without cysts, and diffuse areas of white matter dysmaturation with maturation arrest of the pre-oligodendroglia cells, located in the cerebral white matter.


Felty's Syndrome, Unspecified Shoulder

description: Evidence of Felty's syndrome in an unspecified shoulder.


name: Pre-Existing Type 2 Diabetes Mellitus, in Childbirth

description: Evidence of pre-existing type 2 diabetes mellitus in childbirth.


Gastric Hodgkin's Lymphoma

description: An extremely rare Hodgkin lymphoma that arises from the stomach.


name: Bladder Cancer pTis TNM Finding v6 and v7

description: Bladder cancer with a finding of carcinoma in situ: 'flat tumor'. (from AJCC 6th and 7th Eds.)


Amnesia, CTCAE

description: A disorder characterized by systematic and extensive loss of memory.


name: Cervical high grade squamous intraepithelial lesion

description: A precancerous neoplastic process that affects the cervical squamous epithelium. It is usually associated with human papillomavirus infection. It is classified as cervical squamous intraepithelial neoplasia 2 when there is nuclear atypia in both the upper and lower epithelial layers, mitotic figures are confined to the basal two-thirds of the epithelium, and maturation is present in the upper half of the epithelium. It is classified as cervical squamous intraepithelial neoplasia 3 when there is nuclear atypia and mitotic figures throughout the entire thickness of the epithelium, and maturation is absent or confined to the upper third of the epithelium.


name: Grade 5 Infusion Related Reaction, CTCAE

description: Death


name: Pathologic Stage II Esophageal Adenocarcinoma AJCC v8

description: Stage II includes: IIA: (T2, N0, M0, G3); (T2, N0, M0, GX); IIB: (T1, N1, M0, Any G); (T3, N0, M0, Any G). T2: Tumor invades the muscularis propria. T1: Tumor invades the lamina propria, muscularis mucosae, or submucosa. T3: Tumor invades adventitia. N0: No regional lymph node metastasis. N1: Tumor with metastasis in one or two regional lymph nodes. M0: No distant metastasis. GX: Grade cannot be assessed. G3: Poorly differentiated, undifferentiated. (AJCC 8th ed.)


T1a TNM Finding

description: A general term that refers to a TNM finding of a primary tumor limited to the site of growth.  The definition of T1a TNM finding depends on the specific type of cancer that it refers to; for example, for breast cancer it refers to a primary tumor that is more than 0.1cm, but not more than 0.5 cm in greatest dimension; for kidney cancer it refers to a primary tumor that is 4 cm or less in greatest dimension; and for thyroid cancer it refers to a primary tumor that is 1 cm or less in greatest dimension.


description: A meningioma that arises within the cranial cavity and results from exposure to radiation.


Astrocytoma, IDH-Wildtype

description: Astrocytoma lacking mutations in IDH1 or IDH2 genes. It includes diffuse astrocytoma, IDH-wildtype and anaplastic astrocytoma, IDH-wildtype.


Breast Cancer cN2b TNM Finding v8

description: Breast cancer with metastases only in ipsilateral internal mammary nodes in the absence of axillary lymph node metastases. (from AJCC 8th Ed.)


name: Diffuse Follicular Center Lymphoma, Lymph Nodes of Head, Face, and Neck

description: Evidence of diffuse follicular center lymphoma, lymph nodes of head, face, and neck.


name: Drug or Chemical Induced Diabetes Mellitus with Moderate Non-Proliferative Diabetic Retinopathy without Macular Edema, Bilateral

description: Evidence of drug or chemical induced diabetes mellitus with moderate non-proliferative diabetic retinopathy without macular edema that is bilateral.


name: Grade 3 Neonatal Intraventricular Hemorrhage, AE

description: An adverse event in a newborn characterized by hemorrhage occupying greater than 50% of the ventricle volume; ventricular dilatation greater than 4mm above the 97th percentile; parenchymal venous infarction; requiring temporizing neurosurgical procedure (drain, shunt or reservoir).


Grade 4 Hallucinations, CTCAE

description: Life-threatening consequences, threats of harm to self or others; hospitalization indicated


name: Stage IA Ampulla of Vater Cancer AJCC v7

description: Stage IA includes: T1, N0, M0. T1: Tumor limited to ampulla of Vater or sphincter of Oddi.  N0: No regional lymph node metastasis.  M0: No distant metastasis. (from AJCC 7th Ed.)


name: Locally Advanced Malignant Skin Neoplasm

description: A malignant neoplasm of the skin that has spread from its original site of growth to nearby tissues or lymph nodes.


name: Grade 2 Fallopian Tube Anastomotic Leak, CTCAE

description: Symptomatic; medical intervention indicated


Grade 2 Mucosal Infection, CTCAE

description: Oral intervention indicated (e.g., antibiotic, antifungal, or antiviral)


Grade 4 Pericardial Tamponade, CTCAE

description: Life-threatening consequences; urgent intervention indicated


Hyperattenuation

description: Describes areas on an x-ray or CT scan that show up as brighter than surrounding tissues.


name: Other Atherosclerosis of Non-Biological Bypass Graft(s) of the Extremities, Left Leg

description: Evidence of other atherosclerosis of non-biological bypass graft(s) of the extremities in the left leg not specified elsewhere.


name: Soft Tissue Sarcoma of the Retroperitoneum Clinical TNM Finding v8

description: A clinical finding about one or more characteristics of soft tissue sarcoma of the retroperitoneum, following the rules of the TNM AJCC v8 classification system.


name: Unresectable Platinum-Resistant Fallopian Tube Carcinoma

description: A platinum-resistant fallopian tube carcinoma that is not amenable to surgical resection.


name: Unresectable Oligodendroglioma, IDH-Mutant and 1p/19q-Codeleted

description: Oligodendroglioma, IDH-mutant and 1p/19q-codeleted that is not amenable to surgical resection.


Myolipoma

description: A benign extrauterine tumor composed of mature adipocytes and smooth muscle cells.


HLA-A Match Finding

description: The extent of HLA-A matching between the donor and the recipient.


Glandular odontogenic cyst

description: A developmental odontogenic cyst with epithelial features that simulate salivary gland or glandular differentiation. (WHO 2017)


name: Stage IIIA Merkel Cell Carcinoma AJCC v7

description: Stage IIIA includes: Any T, N1a, M0.  N1a: Micrometastasis in regional lymph nodes.  M0: No distant metastasis.  (AJCC 7th Ed.)


name: Esophagus Mucositis or Stomatitis by Clinical Examination Classification, CTCAE


name: Malignant neoplasm overlapping female genital organ site

description: Evidence of a malignant neoplasm of overlapping sites of the female genital organs.


Vulvar Tubulovillous Adenoma

description: An intestinal-type adenoma that arises from the vulva. It is characterized by the presence of a tubulovillous architectural pattern.


Grade 2 Epistaxis, CTCAE

description: Moderate symptoms; medical intervention indicated (e.g., nasal packing, cauterization; topical vasoconstrictors)


Supraglottic Cancer cM0 TNM Finding v7

description: Supraglottic cancer without evidence of distant metastasis. (from AJCC 7th Ed.)


name: Grade 1 Intraoperative Ocular Injury, CTCAE

description: Primary repair of injured organ/structure indicated


name: FIGO Stage IVB Gestational Trophoblastic Tumor


Benign Thalamic Neoplasm

description: A neoplasm that arises from the thalamus and is characterized by the absence of atypical or malignant cytological and architectural features, and absence of invasive features or metastatic potential.


Grade 5 Tracheal Mucositis, CTCAE

description: Death


Grade 3 Guillain-Barre Syndrome, CTCAE

description: Severe symptoms; limiting self care ADL


Nodular and Massive Retinal Gliosis

description: A spectrum of discrete retinal glial proliferations surrounding blood vessels, ranging in size from small nodules to massive lesions that fill the eye. (WHO 2018)


Conventional Schwannoma

description: A common, usually encapsulated benign nerve sheath tumor composed of well-differentiated Schwann cells.


Accidental Vehicle Fire Smoke Exposure

description: Environmental or occupational exposure to airborne gases and particulates produced during a vehicle fire that was not caused by deliberate human actions.


name: Urethral Cancer Pathologic Distant Metastasis TNM Finding v8

description: A pathologic finding about one or more characteristics of urethral cancer, following the rules of the TNM AJCC v8 classification system as they pertain to distant metastases.


Borderline Broad Ligament Serous Tumor

description: A rare non-invasive tumor that arises from the broad ligament. It is characterized by the presence of serous epithelial cell proliferation and cytological atypia.


name: Breast Cancer pT1mic TNM Finding v6 and v7

description: Breast cancer with tumor size 0.1 cm or less in greatest dimension (microinvasion). (from AJCC 6th and 7th Eds.)


Lymphosarcoma of spleen

description: An antiquated term that refers to a non-Hodgkin lymphoma composed of small and medium sized lymphocytes affecting the spleen.


name: Secondary Malignant Neoplasm of Left Kidney and Renal Pelvis

description: Evidence of secondary malignant neoplasm of the left kidney and renal pelvis.


Grade 3 Myocardial Infarction, CTCAE

description: Severe symptoms; cardiac enzymes abnormal; hemodynamically stable; ECG changes consistent with infarction


name: Other aplastic anemias and other bone marrow failure syndromes

description: Evidence of other aplastic anemias and other bone marrow failure syndromes not specified elsewhere.


name: Grade 4 Ureter Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


name: Metastatic Digestive System Neuroendocrine Neoplasm

description: A neuroendocrine neoplasm that arises from any part of the digestive system and has metastasized to another anatomic site.


Ache

description: A dull persistent (usually moderately intense) pain.


name: Atypical Chronic Myeloid Leukemia, BCR-ABL Negative not Having Achieved Remission

description: Evidence of atypical chronic myeloid leukemia, BCR-ABL negative not having achieved remission.


Thrombotic Disorder

description: A disorder in which there is pathological development of blood clots within the cardiovascular system.


name: Primary cutaneous acral CD8 positive T-cell lymphoma

description: A primary cutaneous T-cell lymphoproliferative disorder that presents as an acral (peripheral) lesion. It is composed of CD8-positive neoplastic T-lymphocytes. It is usually localized to a single site and has an indolent clinical course. Local or more extensive recurrences have been described in a minority of patients.


Copper Exposure

description: A finding indicating that an individual has been exposed to copper or copper-containing compounds.


Opioid dependence in remission

description: Evidence of opioid dependence, in remission.


Vaginal Hemorrhage, CTCAE

description: A disorder characterized by bleeding from the vagina.


name: Uterine Corpus Adenosarcoma pT2 TNM Finding v8

description: Uterine corpus adenosarcoma with tumor extending beyond the uterus, within the pelvis. (from AJCC 8th Ed.)


name: Grade 3 Joint Intra-Operative Injury, CTCAE


Line Occlusion

description: Blockage of a catheter tube.


Grade 5 Urinary Tract Infection, CTCAE

description: Death


name: Rheumatoid Arthritis of Left Shoulder with Involvement of Organs and Systems

description: Evidence of rheumatoid arthritis of left shoulder with involvement of organs and systems.


Adrenal Cancer pT0 TNM Finding v7

description: Adrenal cancer with no evidence of a primary tumor. (from AJCC 7th Ed.)


name: Grade 2 Ileum Stricture or Stenosis, CTCAE


name: Mucosa Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


Secondary Glioblastoma

description: A glioblastoma arising from a lower grade astrocytoma.


Grade 3 Cholesterol High, CTCAE

description: >400-500 mg/dL; >10.34-12.92 mmol/L


name: Grade 4 Leukemia Secondary To Oncology Chemotherapy, CTCAE

description: Present


description: A lymphoproliferative disorder that occurs in a patient with immunodeficiency.


Recurrent Malignant Glioma

description: The reemergence of malignant glioma after a period of remission.


name: Grade 2 Outer Ear Pinna Intra-Operative Injury, CTCAE


name: Grade 1 Skin Intra-Operative Injury, CTCAE


AIDS-Related Hodgkin Lymphoma

description: Hodgkin lymphoma secondary to AIDS. An increased incidence of Hodgkin lymphomas has been observed in HIV positive patients. Most cases are morphologically classified as lymphocyte depleted or mixed cellularity Hodgkin lymphomas.


name: Muscle Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


name: Solar Radiation-Related Malignant Neoplasm

description: A malignant neoplasm arising in an anatomic site exposed to solar radiation.


name: Grade 2 Anal or Perianal Infection with Unknown Absolute Neutrophil Count, CTCAE


ANO1 Negative

description: An indication that expression of ANO1 has not been detected in a sample.


name: Small Intestine Cancer pT3 TNM Finding v7

description: Small intestine cancer with tumor invading through the muscularis propria into the subserosa or into the nonperitonealized perimuscular tissue (mesentery or retroperitoneum) with extension 2 cm or less.  Note: The nonperitonealized perimuscular tissue is, for jejunum and ileum, part of the mesentery and, for duodenum in areas where serosa is lacking, part of the interface with the pancreas. (from AJCC 7th Ed.)


Pharyngeal Cancer TNM Finding v6

description: A finding about one or more characteristics of pharyngeal cancer, following the rules of the TNM AJCC v6 classification system.


name: Other Generalized Epilepsy, not Intractable, with Status Epilepticus

description: Evidence of other generalized epilepsy with status epilepticus that has some acceptable treatment options not specified elsewhere.


Gastric Cancer Clinical TNM Finding v7

description: A clinical finding about one or more characteristics of gastric cancer, following the rules of the TNM AJCC v7 classification system.  The clinical staging is based on evidence of extent of disease acquired before definitive treatment is instituted.  It includes physical examination, radiologic imaging, endoscopy, biopsy, and laboratory findings.  All cancers should be confirmed histologically. (from AJCC 7th Ed.)


Vulvar Cancer pN1a TNM Finding v7

description: Vulvar cancer with one or two lymph node metastasis each measuring 5 mm or less. (from AJCC 7th Ed.)


name: Malnutrition in Pregnancy, Second Trimester

description: Evidence of malnutrition in pregnancy in the second trimester.


name: Type 2 Diabetes Mellitus with Diabetic Amyotrophy

description: Evidence of type 2 diabetes mellitus with diabetic amyotrophy.


name: Grade 4 Cranial Nerve VI Neuropathy, CTCAE


name: Grade 3 Pleura Intra-Operative Injury, CTCAE


name: Grade 3 Carotid Artery Intra-Operative Injury, CTCAE


name: Grade 1 Mediastinum Intra-Operative Injury, CTCAE


Basal cell hyperplasia

description: A pathologic hyperplastic process characterized by the proliferation of the cells of the epithelial layer that resemble the basal cells of the lower part of the epidermis.


PSA 50 Percent or Greater than Nadir

description: A finding indicating that the blood concentration of prostate specific antigen in a subject's sample has increased by 50 percent or more over the lowest value recorded for a sample from that subject.


Childhood Nervous System Neoplasm

description: A neoplasm that affects the nervous system during childhood.


Alcohol Use Complicating the Puerperium

description: Evidence of alcohol use complicating the puerperium.


name: Drug or Chemical Induced Diabetes Mellitus with Hyperosmolarity without Non-Ketotic Hyperglycemic-Hyperosmolar Coma

description: Evidence of drug or chemical induced diabetes mellitus with hyperosmolarity without non-ketotic hyperglycemic-hyperosmolar coma.


Multilocular Thymic Cyst

description: A multicystic lesion that arises from the epithelial component of the thymus gland.  It is usually associated with the presence of lymphoid follicles and degenerative changes.  Although its etiology is unknown, it has been described in patients with HIV infection and in patients with nodular sclerosis Hodgkin lymphoma affecting the thymus gland.


malnutrition in puerperium

description: Evidence of malnutrition in the puerperium.


Uncomplicated severe persistent asthma

description: Evidence of severe persistent asthma, uncomplicated.


name: Jejunum and Ileum Neuroendocrine Tumor pNX TNM Finding v8

description: Jejunum and ileum neuroendocrine tumor in which the regional lymph nodes cannot be assessed.  (from AJCC 8th Ed.)


name: Colorectal Cancer Clinical Distant Metastasis TNM Finding v8

description: A clinical finding about one or more characteristics of colorectal cancer, following the rules of the TNM AJCC v8 classification system as they pertain to distant metastases.


Other Dermatomyositis with Myopathy

description: Evidence of other dermatomyositis with myopathy not specified elsewhere.


name: Sedative, Hypnotic or Anxiolytic Induced Dependence with Intoxication Delirium

description: Evidence of sedative, hypnotic or anxiolytic induced dependence with intoxication delirium.


Extra-adrenal paraganglioma, malignant

description: An extra-adrenal paraganglioma that metastasizes to regional or distant anatomic sites.  Common sites of metastasis include the lymph nodes, lungs, bones, and liver.


Adult Myofibroma

description: A rare myofibroma that occurs in adults.


name: Grade 3 Trachea Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


PSA Decline Greater than 50 Percent

description: A finding indicating that the blood concentration of prostate specific antigen in a subject's sample has decreased by more than 50 percent compared to the value recorded for a previous sample from that subject.


Increased Intra-Peritoneal Volume

description: Overfill which occurs when there is more than the desired amount of fluid in the abdomen during peritoneal dialysis.


description: Evidence of alcohol dependence with withdrawal delirium.


name: Nasopharyngeal Cancer pM1 TNM Finding v6 and v7

description: Nasopharyngeal cancer with distant metastasis. (from AJCC 6th and 7th Eds.)


name: Gastric Neuroendocrine Tumor Clinical TNM Finding v8

description: A clinical finding about one or more characteristics of a gastric neuroendocrine tumor, following the rules of the TNM AJCC v8 classification system.


Grade 2 Cholecystitis, CTCAE

description: Symptomatic; medical intervention indicated


name: Grade 5 Larynx Obstruction and Stenosis, CTCAE


name: Malignant neoplasm of other specified female genital organs

description: Evidence of a malignant neoplasm of other specified female genital organs.


Solid Nodule

description: Fully opaque attenuation through which no normally arborizing structures are visible.


name: Grade 4 Thoracic Duct Intra-Operative Injury, CTCAE


name: Other Stimulant Abuse with Stimulant-Induced Sleep Disorder

description: Evidence of other stimulant abuse with stimulant-induced sleep disorder not specified elsewhere.


name: Exocrine Pancreatic Cancer Clinical TNM Finding v6


name: Type 1 Diabetes Mellitus with Stable Proliferative Diabetic Retinopathy, Unspecified Eye

description: Evidence of type 1 diabetes mellitus with stable proliferative diabetic retinopathy in an unspecified eye.


name: Type 1 Diabetes Mellitus with Mild Nonproliferative Diabetic Retinopathy without Macular Edema, Unspecified Eye

description: Evidence of type 1 diabetes mellitus with mild nonproliferative diabetic retinopathy without macular edema in an unspecified eye.


Otitis Externa, CTCAE

description: A disorder characterized by an infectious process involving the outer ear and ear canal. Contributory factors include excessive water exposure (swimmer's ear infection) and cuts in the ear canal. Symptoms include fullness, itching, swelling and marked discomfort in the ear and ear drainage.


Subcutaneous edema

description: Presence of edema in subcutaneous connective tissue.


Grade 2 Ileal Fistula, CTCAE

description: Symptomatic, invasive intervention not indicated


name: Unresectable Abdominal Neuroendocrine Neoplasm

description: An abdominal neuroendocrine neoplasm that is not amenable to surgical resection.


name: Grade 4 Joint Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


Cytogenetic Minor Response

description: A minor decrease in abnormal karyotype, based on pre-defined thresholds.


name: Grade 2 Neuroendocrine Prolactin Hormone Secretion Abnormality, CTCAE


Pelvic Rhabdomyosarcoma

description: Rhabdomyosarcoma involving the organs and structures in the pelvis.


Nodular Melanoma

description: A melanoma that arises from the skin and mucosal sites. It is characterized by a vertical growth phase and lacks a significant radial growth phase. It may or may not arise from a pre-existing nevus. Morphologically, it is characterized by the presence of cohesive aggregates of neoplastic melanocytes in the dermis that often exhibit an epithelioid appearance. The overlying epidermis is often involved.


name: Wound Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


name: AIDS-Related Lymphoma by Working Formulation


name: Lugano Classification Stage II Bulky Hodgkin Lymphoma AJCC v8

description: Stage II Bulky: Stage II with disease bulk. (from AJCC 8th Ed.)


name: IWG-MRT Myelodysplastic Syndrome Major Hematologic Improvement-Erythroid Response in High Transfusion Burden

description: Major hematologic improvement-erythroid response in high transfusion burden patients corresponds to transfusion independence, defined by the absence of any transfusions over a period of a minimum of 8 weeks within an observation period of 16 to 24 weeks with the same transfusion policy (defined in "1.2.4. Transfusion policy") compared with 16 weeks prior to treatment. Only a response duration of at least 16 weeks, however, is considered clinically meaningful. (Adapted from Proposals for revised IWG 2018 hematological response criteria in patients with MDS included in clinical trials; Blood 2019 133: 1020-1030)


name: Grade 3 Reduction in Growth Velocity, CTCAE


name: Other Specified Diabetes Mellitus with Proliferative Diabetic Retinopathy without Macular Edema, Bilateral

description: Evidence of other specified diabetes mellitus with proliferative diabetic retinopathy without macular edema that is bilateral not specified elsewhere.


pN3b TNM Finding

description: A pathologic regional lymph node TNM finding. The definition of pN3b finding depends on the particular type of cancer that it refers to; for example, for gastric cancer, pN3b finding is defined as follows: cancer with metastasis in sixteen or more regional lymph nodes. (from AJCC 8th Ed.)


Aggression

description: A verbal or physical act of hostility.


Non-Neoplastic Urethra Disorder

description: A non-neoplastic disorder affecting the urethra.


Recurrent Spindle Cell Sarcoma

description: The reemergence of spindle cell sarcoma after a period of remission.


Unresectable Gallbladder Adenocarcinoma

description: Adenocarcinoma that arises from the gallbladder and is not amenable to surgical resection.


name: Mycosis Fungoides and Sezary Syndrome N1b TNM Finding v8

description: Clone positive. Note: A T-cell clone is defined by polymerase chain reaction (PCR) or Southern blot analysis of the TCR gene. (from AJCC 8th Ed.)


Alcoholic hepatic failure without coma

description: Evidence of alcoholic hepatic failure without coma.


name: Grade 1 Periventricular Leukomalacia, AE

description: An adverse event in a newborn characterized by transient periventricular echodensities persisting greater than seven days and resolving completely.


name: Merkel Cell Carcinoma Clinical TNM Finding v7

description: A clinical finding about one or more characteristics of Merkel cell carcinoma, following the rules of the TNM AJCC v7 classification system. TNM clinical findings are based on clinical inspection and palpation of the involved area and the regional lymph nodes and/or radiologic studies.  The TNM clinical and pathologic primary tumor classifications of Merkel cell carcinoma are the same. (from AJCC 7th Ed.)


Pelvis Cancer pT3b TNM Finding v8

description: Pelvis cancer with tumor spanning two pelvic segments with extraosseous extension and measuring more than 8 cm in greatest dimension. (from AJCC 8th Ed.)


name: Grade 3 Esophagus Intra-Operative Injury, CTCAE


Unidirectional HLA Mismatch

description: The state when a recipient of a hematopoietic stem cell transplantation is not fully matched with their unrelated adult volunteer donor for HLA-A, HLA-B, HLA-C, and HLA-DRB1 and either the recipient or donor is heterozygous at one locus. Occurs when only the donor or recipient is homozygous.


Ankle Fracture, CTCAE

description: A finding of damage to the ankle joint characterized by a break in the continuity of the ankle bone. Symptoms include marked discomfort, swelling and difficulty moving the affected leg and foot.


name: Recurrent Acute Myeloid Leukemia with Recurrent Genetic Abnormalities

description: The reemergence of acute myeloid leukemia with recurrent genetic abnormalities after a period of remission.


name: Usual Prostate Adenocarcinoma with Neuroendocrine Differentiation

description: Acinar adenocarcinoma of the prostate gland characterized by the presence of scattered neuroendocrine cells by immunohistochemistry.


Grade 5 Colonic Perforation, CTCAE

description: Death


name: Grade 2 Disseminated Intravascular Coagulation, CTCAE

description: Laboratory findings with no bleeding


Grade 3 Ear Pain, CTCAE

description: Severe pain; limiting self care ADL


Neurological Examination Finding

description: A finding noted on examination of the functioning of the nervous system.


Benign neoplasm of broad ligament

description: A neoplasm that arises from the broad ligament and is characterized by the absence of atypical or malignant cytological and architectural features, and absence of invasive features or metastatic potential.


name: Mature Plasmacytoid Dendritic Cell Proliferation Associated with Myeloid Neoplasm

description: A clonal proliferation of plasmacytoid dendritic cells in patients with defined myeloid neoplasms. It is characterized by neoplastic proliferations of mature cells with plasmacytoid morphology in the skin, bone marrow, and very rarely, lymph nodes. Patients are predominantly older males.


name: Serous Endometrial Intraepithelial Carcinoma

description: A precursor of endometrial serous adenocarcinoma characterized by the replacement of the normal endometrial cells by malignant glandular cells that resemble the malignant cells of invasive serous adenocarcinoma. The endometrial neoplastic process is non-invasive. It may coexist with invasive endometrial adenocarcinoma or can be associated with metastases outside the uterus, in the absence of invasive endometrial carcinoma.


name: Other Paralytic Syndrome following Cerebral Infarction, Bilateral

description: Evidence of other paralytic syndrome following cerebral infarction that is bilateral not specified elsewhere.


Global Response

description: An indication of response to disease treatment that takes into account multiple body systems.


Major Pathologic Response

description: A major decrease in signs of cancer, supported by pathological examination and based on pre-defined thresholds.


name: Nontraumatic Subarachnoid Hemorrhage from Unspecified Carotid Siphon and Bifurcation

description: Evidence of nontraumatic subarachnoid hemorrhage from unspecified carotid siphon and bifurcation.


name: Grade 5 Neck Infection NOS with Unknown Absolute Neutrophil Count, CTCAE


name: Colorectal Neuroendocrine Tumor pT0 TNM Finding v8

description: Colorectal neuroendocrine tumor with no evidence of primary tumor. (from AJCC 8th Ed.)


Arrhythmia-Induced Cardiomyopathy

description: A reversible cardiomyopathy presumed to result from the presence of arrhythmias, including the tachycardia-induced cardiomyopathy (T-CM), atrial fibrillation-induced cardiomyopathy (AF-CM), and premature ventricular contraction-induced cardiomyopathy (PVC-CM).


Grade 1 Salivary Gland Fistula, CTCAE

description: Asymptomatic


Stage IIA Prostate Cancer AJCC v7

description: Stage IIA includes: (T1a-c, N0, M0, PSA less than 20, Gleason 7); (T1a-c, N0, M0, PSA equal or more than 10 and less than 20, Gleason equal or less than 6); (T2a, N0, M0, PSA less than 20, Gleason equal or less than 7); (T2b, N0, M0, PSA less than 20, Gleason equal or less than 7); (T2b, N0, M0, PSA X, Gleason X). T1a: Tumor incidental histologic finding in 5% or less of tissue resected.  T1b: Tumor incidental histologic finding in more than 5% of tissue resected.  T1c: Tumor identified by needle biopsy (e.g., because of elevated PSA).  T2a: Tumor involves one-half of one lobe or less.  T2b: Tumor involves more than one-half of one lobe, but not both lobes.  cN0: No regional lymph node metastasis.  pN0: No positive regional nodes.  M0: No distant metastasis.  Gleason 7: Moderately differentiated (moderate anaplasia).  Gleason Equal or Less than 6: Well differentiated (slight anaplasia).  (AJCC 7th ed.)


name: Ocular Adnexal Lymphoma pN2 TNM Finding v8

description: Ocular adnexal lymphoma with involvement of lymph node regions of the mediastinum. (from AJCC 8th Ed.)


name: Grade 3 Electrocardiogram QT Corrected Interval Prolonged, CTCAE

description: Average QTc >= 501 ms; >60 ms change from baseline


name: Other Juvenile Arthritis, Unspecified Hand

description: Evidence of other juvenile arthritis in an unspecified hand not specified elsewhere.


Blue rubber bleb nevus syndrome

description: A hemangioma present at birth.  It is characterized by the presence of rubbery skin lesions.


Body Mass Index 34.0-34.9, Adult

description: Evidence of a body mass index of 34.0-34.9 in the adult.


Injury of prostate

description: Trauma to the prostate.


name: Refractory Digestive System Neuroendocrine Neoplasm

description: A digestive system neuroendocrine neoplasm that is resistant to treatment.


name: Jejunum and Ileum Neuroendocrine Tumor Pathologic Regional Lymph Nodes TNM Finding v8

description: A pathologic finding about one or more characteristics of a jejunum and ileum neuroendocrine tumor, following the rules of the TNM AJCC v8 classification system as they pertain to staging of regional lymph nodes.


name: Cutaneous Melanoma Pathologic Primary Tumor TNM Finding v8

description: A pathologic finding about one or more characteristics of cutaneous melanoma, following the rules of the TNM AJCC v8 classification system as they pertain to staging of the primary tumor.


t(11;14) Negative

description: A cytogenetic finding indicating that the translocation t(11;14) has not been detected in a sample.


name: Likely Tumor Complete Metabolic Response by PET

description: A finding of diffuse metabolic activity at the primary tumor or nodal sites that is greater than background uptake but less than liver uptake, detected by PDG-PET.


Corneal Infection, CTCAE

description: A disorder characterized by an infectious process involving the cornea.


name: Grade 3 Small Intestine Infection, CTCAE

description: IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated


name: Ocular Adnexal Lymphoma pT2 TNM Finding v8

description: Ocular adnexal lymphoma with orbital involvement with or without conjunctival involvement. (from AJCC 8th Ed.)


Gastrointestinal Radiation Injury

description: Radiation injury of the gastrointestinal system.


name: Exocrine Pancreatic Cancer pN1 TNM Finding v8

description: Exocrine pancreatic cancer with metastasis in one to three regional lymph nodes. (from AJCC 8th Ed.)


Blood Corticotrophin Decreased

description: A laboratory test result which indicates decreased levels of corticotrophin in the blood.


Grade 1 Uterine Hemorrhage, CTCAE

description: Mild symptoms; intervention not indicated


name: Grade 3 Other Constitutional Symptoms, CTCAE


Severe Sepsis

description: Clinical syndrome defined by the presence of both infection and a systemic inflammatory response that progresses to multi-organ failure.


Thoracoceloschisis

description: A congenital fissure of both the thoracic and abdominal walls.


Grade 2 Depression, CTCAE

description: Moderate depressive symptoms; limiting instrumental ADL


In situ mantle cell neoplasia

description: A neoplastic lymphoid process characterized by the presence of cyclin D1 positive lymphoid cells, typically in the inner mantle zones of lymphoid tissue follicles, in cases that do not suggest the diagnosis of a mantle cell lymphoma. It is often found incidentally and has a low rate of progression.


Bronchial Fistula, CTCAE

description: A disorder characterized by an abnormal communication between the bronchus and another organ or anatomic site.


name: Clinical Stage IV Esophageal Adenocarcinoma AJCC v8

description: Stage IV includes: IVA: (T1-4a, N2, M0); (T4b, N0-2, M0); (Any T, N3, M0); IVB: (Any T, Any N, M1). T1: Tumor invades the lamina propria, muscularis mucosae, or submucosa. T2: Tumor invades the muscularis propria. T3: Tumor invades adventitia. T4a: Tumor invades the pleura, pericardium, azygos vein, diaphragm, or peritoneum. T4b: Tumor invades other adjacent structures, such as the aorta, vertebral body, or airway. N0: No regional lymph node metastasis. N1: Tumor with metastasis in one or two regional lymph nodes. N2: Tumor with metastasis in three to six regional lymph nodes. N3: Tumor with metastasis in seven or more regional lymph nodes. M0: No distant metastasis. M1: Distant metastasis. (AJCC 8th ed.)


name: Pre-Existing Hypertensive Heart Disease Complicating Pregnancy, Third Trimester

description: Evidence of pre-existing hypertensive heart disease complicating pregnancy in the third trimester.


name: Esophagus and Esophagogastric Junction Cancer cM0 TNM Finding v8

description: Esophagus and esophagogastric junction cancer without evidence of distant metastasis. (from AJCC 8th Ed.)


Testicular Disorder, CTCAE

description: A disorder characterized by abnormal function or appearance of the testis.


Small cell carcinoma, fusiform cell

description: A neuroendocrine carcinoma composed of malignant fusiform small cells.


Cervical Cancer pT2a1 TNM Finding v9

description: Cervical carcinoma with involvement limited to the upper two-thirds of the vagina without parametrial invasion measuring 4.0 cm or less in greatest dimension. (from AJCC 9th Ed.)


name: Systemic Hydroa Vacciniforme Lymphoproliferative Disorder

description: Hydroa vacciniforme lymphoproliferative disorder characterized by severe clinical course and associated with fever, lymph node involvement, and involvement of internal organs by EBV-positive T-cells and NK-cells. It usually affects Asian and Latin American individuals.


Local Colorectal Cancer Symptoms

description: Colorectal cancer symptoms that only affect the colon and/or rectum and have not spread to distant organs.


name: Type 2 Diabetes Mellitus with Other Skin Ulcer

description: Evidence of type 2 diabetes mellitus with other skin ulcer.


name: Recurrent Endocervical Adenocarcinoma, Usual-Type

description: The reemergence of endocervical adenocarcinoma, usual-type after a period of remission.


Grade 3 Urinary Incontinence, CTCAE

description: Intervention indicated (e.g., clamp, collagen injections); operative intervention indicated; limiting self care ADL


name: Stage III Renal Pelvis and Ureter Cancer AJCC v8

description: Stage III includes: T3, N0, M0. T3: For renal pelvis only: Tumor invades beyond muscularis into peripelvic fat or into the renal parenchyma. For ureter only: Tumor invades beyond muscularis into periureteric fat. N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 8th ed.)


Gallbladder Cancer pT2b TNM Finding v8

description: Gallbladder cancer with tumor invading the perimuscular connective tissue on the hepatic side, with no extension into the liver. (from AJCC 8th Ed.)


name: Mixed Cellularity Classic Hodgkin Lymphoma, Lymph Nodes of Multiple Sites

description: Evidence of mixed cellularity classic Hodgkin lymphoma, lymph nodes of multiple sites.


name: Peritoneal Cavity Intra-Operative Injury, CTCAE


description: Evidence of inhalant abuse with inhalant-induced mood disorder.


name: Jejunum and Ileum Neuroendocrine Tumor pN2 TNM Finding v8

description: Jejunum and ileum neuroendocrine tumor with large mesenteric masses (larger than 2 cm) and/or extensive nodal deposits (12 or greater), especially those that encase the superior mesenteric vessels. (from AJCC 8th Ed.)


name: Carcinoma in Situ of Skin of Left Upper Eyelid, Including Canthus

description: Evidence of carcinoma in situ of the skin of left upper eyelid including the canthus.


Bile Duct Stenosis, CTCAE

description: A disorder characterized by a narrowing of the lumen of the bile duct.


name: Myeloid Leukemia, Philadelphia- Negative

description: Myeloid leukemia characterized by the absence of Philadelphia chromosome.


name: Duodenum/Ampulla/Jejunum/Ileum Neuroendocrine Tumor pT0 TNM Finding v7

description: Duodenum/ampulla/jejunum/ileum neuroendocrine tumor with no evidence of a primary tumor. (from AJCC 7th Ed.)


name: Grade 4 Electrocardiogram QT Corrected Interval Prolonged, CTCAE

description: Torsade de pointes; polymorphic ventricular tachycardia; signs/symptoms of serious arrhythmia


Grade 5 Jejunal Perforation, CTCAE

description: Death


name: Grade 3 Sinus Infection with Unknown Absolute Neutrophil Count, CTCAE


Grade 4 Enterocolitis, CTCAE

description: Life-threatening consequences; urgent intervention indicated


name: Type 1 Diabetes Mellitus with Diabetic Peripheral Angiopathy with Gangrene

description: Evidence of type 1 diabetes mellitus with diabetic peripheral angiopathy with gangrene.


name: mucinous cystic neoplasm with moderate dysplasia

description: A non-invasive mucinous cystic neoplasm that arises from the pancreas and is characterized by the presence of moderate dysplasia.  The neoplastic columnar mucin-producing epithelial cells form papillary projections or crypt-like invaginations. There is cellular pseudostratification and mitotic activity present.


Hindgut Neuroendocrine Tumor G1

description: A neuroendocrine tumor that arises from the sigmoid colon, descending colon, or rectum.


Stage IA Osteosarcoma AJCC v7

description: Stage IA includes: T1, N0, M0, G1, G2, GX.  T1: Tumor 8 cm or less in greatest dimension.  N0: No regional lymph node metastasis.  M0: No distant metastasis. G1: Well differentiated-low grade.  G2: Moderately differentiated-low grade.  GX: Grade cannot be assessed. (AJCC 7th ed.)


name: Grade 5 Heart Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


Recurrent Chronic Leukemia

description: The reemergence of chronic leukemia after a period of remission.


Gallbladder Fistula, CTCAE

description: A disorder characterized by an abnormal communication between the gallbladder and another organ or anatomic site.


Lung Cancer pM1a TNM Finding v8

description: Lung cancer with separate tumor nodule(s) in a contralateral lobe; tumor with pleural or pericardial nodules or malignant pleural or pericardial effusion. Most pleural (pericardial) effusions with lung cancer are a result of the tumor. In a few patients, however, multiple microscopic examinations of pleural (pericardial) fluid are negative for tumor, and the fluid is nonbloody and not an exudate. If these elements and clinical judgment dictate that the effusion is not related to the tumor, the effusion should be excluded as a staging descriptor. (from AJCC 8th Ed.)


name: Grade 5 Pancreas Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


Thymic Tumor pM1b TNM Finding v8

description: Thymic tumor with pulmonary intraparenchymal nodule or distant organ metastasis. (from AJCC 8th Ed.)


Filiform Serrated Adenoma

description: A traditional serrated adenoma characterized by the presence of prominent villous projections of the neoplastic epithelium.


name: Pre-Existing Essential Hypertension Complicating the Puerperium

description: Evidence of pre-existing essential hypertension complicating the puerperium.


name: Grade 3 Ileum Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


name: Recurrent Acute Panmyelosis with Myelofibrosis

description: The reemergence of acute panmyelosis with myelofibrosis after a period of remission.


name: Rheumatoid nodule of subcutaneous tissue of left elbow

description: Evidence of rheumatoid nodule in the left elbow.


No Response in Aplastic Anemia

description: Worsening of, or no apparent change in, the severity of aplastic anemia in response to treatment, including recurrence of transfusion dependency.


name: Post-Dysenteric Arthropathy, Unspecified Hand

description: Evidence of post-dysenteric arthropathy in an unspecified hand.


name: Grade 4 Gastrointestinal Stoma Intra-Operative Injury, CTCAE


name: Grade 4 Colon Infection with Unknown Absolute Neutrophil Count, CTCAE


Mild epithelial dysplasia

description: A precancerous neoplastic process that affects the squamous, glandular, or transitional cell epithelium without evidence of invasion. It is characterized by the presence of mild epithelial dysplasia.


Neutrophilic dermatosis

description: A type of dermatosis characterized by dense infiltration of neutrophils in the skin without evidence of infection or vasculitis. It may be secondary to an underlying systemic illness.


Colorectal Cancer pN1c TNM Finding v8

description: Colorectal cancer in which no regional lymph nodes are positive, but there are tumor deposits in the subserosa, mesentery, or nonperitonealized pericolic, or perirectal/mesorectal tissues. (from AJCC 8th Ed.)


name: Renal Pelvis and Ureter Cancer Clinical Distant Metastasis TNM Finding v8

description: A clinical finding about one or more characteristics of renal pelvis and ureter cancer, following the rules of the TNM AJCC v8 classification system as they pertain to distant metastases.


name: Lip and Oral Cavity Cancer Clinical TNM Finding v8

description: A clinical finding about one or more characteristics of lip and oral cavity cancer, following the rules of the TNM AJCC v8 classification system.  The assessment of the primary tumor is based on inspection and palpation of the oral cavity and neck.  Additional studies may include CT, MRI, or ultrasound.  (from AJCC 8th Ed.)


name: Grade 3 Alanine Aminotransferase Increased, CTCAE

description: >5.0-20.0 x ULN if baseline was normal; >5.0-20.0 x baseline if baseline was abnormal


Partial Remission

description: A finding indicating that there is a decrease in the size and the extent of tissue involvement by a malignant tumor in a patient.


Non-Neoplastic Cardiovascular Disorder

description: A non-neoplastic disorder that affects the heart and/or vessels.  Representative examples include myocardial infarction, endocarditis, arteriosclerosis, thrombosis, and lymphedema.


name: Locally Advanced Bladder Urothelial Carcinoma

description: A bladder urothelial carcinoma that has spread from its original site of growth to nearby tissues or lymph nodes.


Grade 2 Intestinal Stoma Leak, CTCAE

description: Symptomatic; medical intervention indicated


Paralytic syndrome

description: Evidence of paralytic syndrome.


Grade 3 Duodenal Stenosis, CTCAE

description: Severely altered GI function; tube feeding or hospitalization indicated; elective operative intervention indicated


name: Subglottic Cancer pTX TNM Finding v6 and v7

description: Subglottic cancer in which the primary tumor cannot be assessed. (from AJCC 6th and 7th Eds.)


name: Oropharyngeal Cancer Pathologic Distant Metastasis TNM Finding v7

description: A pathologic finding about one or more characteristics of oropharyngeal cancer, following the rules of the TNM AJCC v7 classification system as they pertain to distant metastases.  There is no pathologic M0 for oropharyngeal cancer.