name: Locally Advanced Pancreatobiliary Carcinoma

description: A carcinoma that arises from the pancreas, bile ducts, gallbladder, or ampulla of Vater and has spread from its original site of growth to nearby tissues or lymph nodes.


Grade 4 Rash Desquamation, CTCAE

category: biolink:PhenotypicFeature biolink:DiseaseOrPhenotypicFeature biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing


name: Locally Advanced Gastroesophageal Junction Adenocarcinoma

category: biolink:Disease biolink:DiseaseOrPhenotypicFeature biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing

description: Gastroesophageal junction adenocarcinoma that has spread to nearby tissues or lymph nodes.


name: Spinal Cord Intra-Operative Injury, CTCAE


name: Melanoma of the Conjunctiva Pathologic Regional Lymph Nodes TNM Finding v7

description: A pathologic finding about one or more characteristics of melanoma of the conjunctiva, following the rules of the TNM AJCC v7 classification system as they pertain to staging of regional lymph nodes.


Grade 3 Mucosal Infection, CTCAE

description: IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated


Grade 2 Infective Myositis, CTCAE

description: Localized; local intervention indicated (e.g., topical antibiotic, antifungal, or antiviral)


name: Grade 2 Eye Infection NOS Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


name: Ocular Adnexal Lymphoma pT1c TNM Finding v7

description: Extensive conjunctival involvement. (from AJCC 7th Ed.)


name: Malignant neoplasm of anterior mediastinum

description: Evidence of a malignant neoplasm of the anterior mediastinum.


name: Adenocarcinoma with neuroendocrine differentiation

description: An invasive adenocarcinoma characterized by the presence of focal or extensive neuroendocrine differentiation.


Non-Target Enhancing Lesion Response

description: An assessment of the response to the therapy of the non-target enhancing lesion.


name: Injury, Poisoning and Procedural Complications - Other, Specify, CTCAE


T1b1 TNM Finding

description: A general term that refers to a TNM finding of a primary tumor limited to the site of growth. The definition of T1b1 TNM finding depends on the specific type of cancer to which it refers: for example, for cervical carcinoma it indicates measured stromal invasion measuring more than 5 mm in depth and equal or less than 2 cm in greatest dimension.


description: Evidence of cocaine dependence with cocaine-induced psychotic disorder with delusions.


name: Hypopharyngeal Cancer Pathologic Distant Metastasis TNM Finding v6

description: A pathologic finding about one or more characteristics of hypopharyngeal cancer, following the rules of the TNM AJCC v6 classification system as they pertain to distant metastases.


Grade 1 Uterine Obstruction, CTCAE

description: Asymptomatic; clinical or diagnostic observations only; intervention not indicated


name: Pauciarticular Juvenile Rheumatoid Arthritis, Right Hip

description: Evidence of pauciarticular juvenile rheumatoid arthritis in the right hip.


Cutaneous Langerhans cell histiocytosis

description: Langerhans cell histiocytosis that affects the skin. It manifests with skin papules and plaques.


name: Grade 4 Gingiva Intra-Operative Injury, CTCAE


name: Atherosclerosis of Native Arteries of Left Leg with Ulceration of Thigh

description: Evidence of atherosclerosis of native arteries of left leg with ulceration of thigh.


Gallbladder Cancer pN2 TNM Finding v7

description: Gallbladder cancer with metastases to periaortic, pericaval, superior mesenteric artery, and/or celiac artery lymph nodes. (from AJCC 7th Ed.)


name: Gastric Neuroendocrine Tumor cM0 TNM Finding v8

description: Gastric neuroendocrine tumor without evidence of distant metastasis. (from AJCC 8th Ed.)


name: Grade 1 Hepatic Artery Intra-Operative Injury, CTCAE


Malignant neoplasm of stomach stage I

description: Stage I includes: IA (T1, N0, M0); IB (T2, N0, M0); (T1, N1, M0).  T1: Tumor invades lamina propria, muscularis mucosae, or submucosa.  T2: Tumor invades the muscularis propria. N0: No regional lymph node metastasis.  N1: Metastasis in 1-2 regional lymph nodes. M0: No distant metastasis. (AJCC 7th ed.)


Organomegaly

description: An abnormal enlargement of an organ, particularly an organ of the abdominal cavity.


description: Evidence of inhalant dependence with inhalant-induced mood disorder.


Phantom Pain, CTCAE 5.0

description: A disorder characterized by a sensation of marked discomfort related to a limb or an organ that is removed from or is not physically part of the body.


name: atherosclerosis of other type of bypass graft of right leg with ulceration of thigh

description: Evidence of atherosclerosis of other type of bypass graft(s) of the right leg with ulceration of thigh.


name: Nasopharyngeal Cancer pT1 TNM Finding v8

description: Nasopharyngeal cancer with tumor confined to the nasopharynx, or tumor extending to oropharynx and/or nasal cavity without parapharyngeal involvement. (from AJCC 8th Ed.)


name: Cutaneous Squamous Cell Carcinoma of the Head and Neck cN2a TNM Finding v8

description: Cutaneous squamous cell carcinoma of the head and neck with metastasis in a single ipsilateral lymph node larger than 3 cm but not larger than 6 cm in greatest dimension and ENE(-). (from AJCC 8th Ed.)


name: Grade 2 Cornea Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


name: Radiating Chest Pain Along Right Anterior Axillary Line

description: The location of the radiating chest pain is along the right anterior axillary line.


name: Grade 3 Nasal Cavity and Paranasal Sinus Reactions, CTCAE


name: Grade 4 Other Hepatobiliary and Pancreas, CTCAE


name: Gastrointestinal Stromal Tumor Clinical TNM Finding v8

description: A clinical finding about one or more characteristics of gastrointestinal stromal tumor, following the rules of the TNM AJCC v8 classification system.


name: Juvenile Dermatomyositis with Other Organ Involvement

description: Evidence of juvenile dermatomyositis with other organ involvement.


Nontraumatic extradural hemorrhage

description: Bleeding into the epidural space that is not associated with physical trauma.


Stage I Hodgkin Lymphoma

description: Ann Arbor Classification: Stage I: Involvement of a single lymph node region (I); or localized involvement of a single extralymphatic organ or site in the absence of any lymph node involvement (IE) (rare in Hodgkin lymphoma).


Gastroparesis, CTCAE

description: A disorder characterized by an incomplete paralysis of the muscles of the stomach wall resulting in delayed emptying of the gastric contents into the small intestine.


name: Rheumatoid Arthritis of Unspecified Hip with Involvement of Organs and Systems

description: Evidence of rheumatoid arthritis of unspecified hip with involvement of organs and systems.


name: Grade 3 Oculomotor Nerve Disorder, CTCAE

description: Severe symptoms; limiting self care ADL


48,XXXX Karyotype

description: An abnormal sex chromosome karyotype where the individual has four copies of the X chromosome. The normal autosomal karyotype is present.


name: Muscle Infection with Unknown Absolute Neutrophil Count, CTCAE


Caustic injury

description: Tissue corrosion or chemical burn.


Grade 4 Abdominal Infection, CTCAE

description: Life-threatening consequences; urgent intervention indicated


Breast Adenolipoma

description: A breast hamartoma characterized by the presence of adipose tissue that contains entrapped glands.


name: Pathologic Stage IVB Esophageal Adenocarcinoma AJCC v8

description: Stage IVB includes: Any T, Any N, M1, Any G. M1: Distant metastasis. (AJCC 8th ed.)


name: Grade 2 Pancreas Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


KIT Gene Mutation Negative

description: A genetic finding indicating that KIT gene mutations have not been detected in a sample.


name: Uterus Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


name: Adult Acute Myeloid Leukemia with Maturation

description: An acute myeloid leukemia with maturation occurring in adults.


Atrial Flutter, CTCAE

description: A disorder characterized by a dysrhythmia with organized rhythmic atrial contractions with a rate of 200-300 beats per minute. The rhythm disturbance originates in the atria.


name: Grade 3 Abdomen Infection NOS with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


Grade 4 Suicidal Ideation, CTCAE

description: Specific plan to commit suicide with serious intent to die which requires hospitalization


name: Hemoglobin Beta Heterozygous Hemoglobin E Plus Null Genotype

description: A genetic finding indicating that one copy of chromosome 16 has a hemoglobin beta gene (HBB) with a mutation that produces a hemoglobin subunit beta variant, the hemoglobin beta E variant, where the glutamic acid residue at position 27 has been replaced by lysine (BE) and the other copy has HBB loss of function or gene deletion mutations (B0). This genotype is associated with beta thalassemia intermedia.


Tertiary Parathyroid Gland Hyperplasia

description: Parathyroid gland hyperplasia that results from progression of secondary hyperparathyroidism in which the parathyroid glands secrete parathyroid hormone autonomously, despite the presence of elevated parathyroid hormone and calcium levels in the serum.


Grade 5 Hematoma, CTCAE

description: Death


Adult Oligodendroglial Tumor

description: An oligodendroglial tumor of the central nervous system occurring in adults.


name: Grade 2 Small Bowel Infection NOS with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


Testicular Cancer pN3 TNM Finding v8

description: Testicular cancer with metastasis with a lymph node mass larger than 5 cm in greatest dimension. (from AJCC 8th Ed.)


name: Inhalant Use, Unspecified with Inhalant-Induced Psychotic Disorder, Unspecified

description: Evidence of inhalant use, unspecified with inhalant-induced psychotic disorder.


name: Ocular Adnexal Lymphoma pT0 TNM Finding v7

description: No evidence of lymphoma. (from AJCC 7th Ed.)


Recurrent disease

description: The return of a disease after a period of remission.


name: Grade 1 Biliary Tree Common Bile Duct Intra-Operative Injury, CTCAE


Genetic Finding

description: A laboratory test result that indicates the status of a molecular genetic or cytogenetic event in a pathologic process.


Lung Progression GvHD

description: Either a decrease by 10% predicted absolute value of %FEV1 or an NIH lung symptom score that has increased by 1 or more points, except 0 to 1.


name: Grade 3 Colon Stricture or Stenosis, CTCAE


Grade 1 Weight Gain, CTCAE

description: 5-<10% from baseline


name: Grade 5 Larynx Mucositis or Stomatitis by Functional or Symptomatic Classification, CTCAE


Grade 2 Sinus Tachycardia, CTCAE

description: Symptomatic; non-urgent medical intervention indicated


Pedunculated Lesion

description: A lesion connected to the underlying tissue by a small stalk.


Tumor Mass

description: A benign or malignant pathologic structure in any part of the body, resulting from a neoplastic accumulation of cells.


name: Cerebral Infarction due to Embolism of Unspecified Cerebellar Artery

description: Evidence of cerebral infarction due to an embolism of an unspecified cerebellar artery.


Rash Acneiform, CTCAE

description: A disorder characterized by an eruption of papules and pustules, typically appearing in face, scalp, upper chest and back.


Lung Cancer pM1 TNM Finding v8

description: Lung cancer with distant metastasis. (from AJCC 8th Ed.)


Recurrent Myelofibrosis

description: The reemergence of myelofibrosis after a period of remission.


Metastatic Mesonephric Adenocarcinoma

description: Mesonephric adenocarcinoma that has spread from its original site of growth to another anatomic site.


Grade 3 Hemolysis, CTCAE

description: Transfusion or medical intervention indicated (e.g., steroids)


name: Locally Advanced Genitourinary System Carcinoma

description: A genitourinary system carcinoma that has spread from its original site of growth to nearby tissues or lymph nodes.


Other secondary thrombocytopenia

description: Evidence of other secondary thrombocytopenia not specified elsewhere.


Post-kala-azar dermal leishmaniasis

description: A cutaneous form of leishmaniasis which sometimes occurs after visceral leishmaniasis treatment.  It is characterized by hypo-pigmented macules, papules, plaques, nodules, or facial erythema; and is considered to be a durable infection reservoir for visceral leishmaniasis.


Oligoclonal Bands

description: The presence of more than one immunoglobulin band in the serum, urine, or cerebrospinal fluid. It usually results from infectious or immunologic disorders.


Grade 2 Pruritus, CTCAE

description: Widespread and intermittent; skin changes from scratching (e.g., edema, papulation, excoriations, lichenification, oozing/crusts); oral intervention indicated; limiting instrumental ADL


Vulvar Cancer by AJCC v8 Stage

description: A term that refers to the staging of vulvar cancer according to the American Joint Committee on Cancer, 8th edition. This staging system applies to all carcinomas of the vulva. Melanoma of the vulva is staged according to the classification for melanoma of the skin. (AJCC 8th Ed.)


atheroembolism of left lower extremity

description: Evidence of atheroembolism of left lower extremity.


name: Grade 3 Dental-Tooth Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


Grade 5 Aspiration, CTCAE

description: Death


Drug exposure via breast milk

description: Ingestion of drugs contained in breast milk.


Grade 3 Retinopathy of Prematurity, AE

description: An adverse event in a newborn characterized by type 1 prethreshold retinopathy of prematurity (ROP) (zone 1 any stage with plus disease; zone 1 International Classification of Retinopathy of Prematurity (ICROP) stage 3 without plus disease; zone 2 ICROP stage 2 or 3 with plus disease); threshold ROP; requiring major care changes (e.g. laser intervention, intravitreal anti-VEGF therapy or operative management).


IgA Monoclonal Gammopathy

description: An abnormal laboratory test result indicating the presence of IgA monoclonal immunoglobulin in the blood or urine.


name: Complete Response of Multiple Myeloma or Plasma Cell Leukemia

description: Complete response of multiple myeloma or plasma cell leukemia is characterized by negative immunofixation on serum and urine samples, and disappearance of any soft tissue plasmacytomas, and less than 5% plasma cells in the bone marrow (confirmation with repeat bone marrow biopsy not needed). Complete response requires two consecutive assessments made at any time before the institution of any new therapy, and no known evidence of progressive or new bone lesions if radiographic studies were performed; radiographic studies are not required to satisfy complete response requirements.


name: Occlusion and Stenosis of Left Carotid Artery

description: Evidence of occlusion and stenosis of left carotid artery.


name: Unspecified Malignant Neoplasm Skin of Left Upper Limb, Including Shoulder

description: Evidence of unspecified malignant neoplasm skin of the left upper limb including the shoulder.


KRAS Gene Mutation Negative

description: A genetic finding indicating that KRAS gene mutations have not been detected in a sample.


name: Grade 5 Encephalomyelitis Infection, CTCAE

description: Death


Grade 1 Bloating, CTCAE

description: No change in bowel function or oral intake


name: Breast Cancer Clinical Distant Metastasis TNM Finding v8

description: A clinical finding about one or more characteristics of breast cancer, following the rules of the TNM AJCC v8 classification system as they pertain to distant metastases.


Abnormal Blood Antidiuretic Hormone

description: A laboratory test result which indicates abnormal levels of antidiuretic hormone in the blood.


name: Digestive System Neuroendocrine Tumor G3

description: A well differentiated, high grade neoplasm with neuroendocrine differentiation that arises from the digestive system. The Ki-67 index is higher than 20%.


Hematologic Response

description: An evaluation of the hematologic response of the disease to the therapy.


Intra-Abdominal Hemorrhage, CTCAE

description: A disorder characterized by bleeding in the abdominal cavity.


name: Monoplegia of Lower Limb Affecting Left Non-Dominant Side

description: Evidence of monoplegia of lower limb affecting left non-dominant side.


Foregut Neuroendocrine Tumor G1

description: A neuroendocrine tumor grade 1 that arises from the esophagus, stomach, or duodenum.


name: Follicular Lymphoma Grade IIIa, Lymph Nodes of Inguinal Region and Lower Limb

description: Evidence of follicular lymphoma grade IIIa in the lymph nodes of inguinal region and lower limb.


name: Grade 1 Esophagus Stricture or Stenosis, CTCAE


name: Grade 4 Central Nervous System Hemorrhage, CTCAE


Low lying placenta

description: A condition in which the placental edge is within 2 cm of but not covering the cervical os.


name: Malignant neoplasm of connective and soft tissue of abdomen

description: Evidence of a malignant neoplasm of connective and soft tissue of abdomen.


manic episode in partial remission

description: Evidence of manic episode in partial remission.


Refractory Prostate Adenocarcinoma

description: Prostate adenocarcinoma that is resistant to treatment.


name: Atherosclerosis of Autologous Vein Bypass Graft(s) of Other Extremity with Ulceration

description: Evidence of atherosclerosis of autologous vein bypass graft(s) of other extremity with ulceration.


name: Grade 5 Upper Airway Infection NOS with Unknown Absolute Neutrophil Count, CTCAE


Childhood Mullerian Papilloma

description: Mullerian papilloma that occurs during childhood.


name: Metastatic Gastroesophageal Junction Adenocarcinoma

description: Gastroesophageal junction adenocarcinoma which has spread from its original site of growth to another anatomic site.


Non dystrophic myotonia

description: A group of rare skeletal muscle ion-channel disorders caused by genetic mutations in the sodium and chloride channel genes. It is characterized by altered membrane excitability resulting in skeletal muscle stiffness. This group of myotonias is distinct from myotonic dystrophy because of the absence of systemic features or progressive weakness.


name: Malignant Neoplasm of Overlapping Sites of Unspecified Eye and Adnexa

description: Evidence of a malignant neoplasm of overlapping sites of unspecified eye and adnexa.


Traditional Serrated Adenoma

description: An adenoma that arises from the large intestine and the appendix.  It is characterized by prominent serration of the glands.


name: Acute on chronic graft-versus-host disease

description: Sudden decompensation of chronic graft versus host disease.


name: Grade 3 Neuroendocrine Prolactin Hormone Secretion Abnormality, CTCAE


Cervical Cancer cTX TNM Finding v8

description: Cervical cancer in which primary tumor cannot be assessed. (from AJCC 8th Ed.)


Head and Neck Cancer cN3 TNM Finding v8

description: Head and neck cancer with metastasis in a lymph node larger than 6 cm in greatest dimension and ENE(-); or metastases in a single ipsilateral lymph node ENE(+); or metastases in multiple ipsilateral, contralateral, or bilateral lymph nodes, any with ENE(+). (from AJCC 8th Ed.)


Gallbladder Neuroendocrine Tumor G1

description: A well differentiated, low grade neuroendocrine neoplasm that arises from the gallbladder. The mitotic count is less than 2 per 10 HPF and/or the Ki67 index is equal to or less than 2 percent.


name: Mycosis Fungoides and Sezary Syndrome B0a TNM Finding v7

description: Clone negative.  Note: A T-cell clone is defined by PCR or Southern blot analysis of the T-cell receptor gene.  (from AJCC 7th Ed.)


Secondary malignant neoplasm of vulva

description: A malignant neoplasm that has spread to the vulva from another anatomic site.


Grade 3 Injection Site Reaction, CTCAE

description: Ulceration or necrosis; severe tissue damage; operative intervention indicated


name: Pleural Mesothelioma Clinical Distant Metastasis TNM Finding v7

description: A clinical finding about one or more characteristics of pleural mesothelioma, following the rules of the TNM AJCC v7 classification system as they pertain to distant metastases.


name: Carcinoma in Situ of Skin of Right Eyelid, Including Canthus

description: Evidence of carcinoma in situ of the skin of right eyelid including the canthus.


name: Grade 1 Cranial Nerve IV Intra-Operative Injury, CTCAE


name: Grade 3 Abdomen NOS Intra-Operative Injury, CTCAE


name: Malignant Melanoma of Left Lower Limb, Including Hip

description: Evidence of a malignant melanoma of the left lower limb including the hip.


Biliary Colic

description: Painful sensation in the gallbladder region.


Choking

description: Interference with respiration by compression or obstruction of the larynx or trachea.


Patient's Condition Stable

description: An indication that the patient’s condition is stable.


Pharyngeal Necrosis, CTCAE

description: A disorder characterized by a necrotic process occurring in the pharynx.


name: Grade 5 Peripheral Nerve Infection with Unknown Absolute Neutrophil Count, CTCAE


Global Complete Response in Lymph Nodes

description: All lymph nodes are now 1.5 cm or less in greatest transverse (long axis) diameter by method used to assess lymph nodes at baseline or biopsy negative for lymphoma; in addition, lymph nodes that were N3 classification and 1.5 cm or less in their long axis and more than 1 cm in their short axis at baseline, must now be 1 cm or less in their short axis or biopsy negative for lymphoma.


Cervical Cancer pT1b TNM Finding v8

description: Cervical cancer with clinically visible lesion confined to the cervix or microscopic lesion greater than T1a/IA2. It includes all macroscopically visible lesions, even those with superficial invasion. (from AJCC 8th Ed.)


name: Other Specified Diabetes Mellitus with Severe Nonproliferative Diabetic Retinopathy without Macular Edema, Unspecified Eye

description: Evidence of other specified diabetes mellitus with severe nonproliferative diabetic retinopathy without macular edema, unspecified eye not specified elsewhere.


Grade 3 Fracture, CTCAE

description: Severe symptoms; displaced or open wound with bone exposure; limiting self care ADL; operative intervention indicated


Grade 3 Photophobia, CTCAE

description: Limiting self care ADL


name: Leiomyosarcoma and Endometrial Stromal Sarcoma pT1a TNM Finding v7

description: Tumor 5 cm or less in greatest dimension. (from AJCC 7th Ed.)


Stage IA Merkel Cell Carcinoma AJCC v7

description: Stage IA includes: T1, pN0, M0.  T1: Primary tumor equal or less than 2 cm in size.  pN0: No regional lymph node metastasis by pathologic examination.  M0: No distant metastasis.  (AJCC 7th Ed.)


description: Evidence of inhalant abuse with inhalant-induced anxiety disorder.


name: Other Generalized Epilepsy, not Intractable, without Status Epilepticus

description: Evidence of other generalized epilepsy without status epilepticus that has some acceptable treatment options not specified elsewhere.


Testosterone Greater than 120 ng/dL

description: A semiquantitative finding indicating that the concentration of testosterone in a sample is greater than 120 ng/dL.


Borderline Exocrine Pancreatic Neoplasm

description: A group of epithelial neoplasms that arise from the exocrine pancreatic tissue and have the potential to evolve into invasive malignant neoplasms.  This group includes the pancreatic intraepithelial neoplasias, non-invasive pancreatic mucinous-cystic neoplasms, pancreatic intraductal papillary-mucinous neoplasms, and pancreatic intraductal tubulopapillary neoplasms.


name: Metastatic Anal Canal Squamous Cell Carcinoma

description: Anal canal squamous cell carcinoma that has spread from its original site of growth to another anatomic site.


S-Beta Thalassemia

description: A disorder characterized by the body's inability to synthesize beta-globin chains, leading to the formation of abnormal hemoglobin and anemia. This inherited autosomal recessive blood disorder is caused by germline mutation of the HBB gene.


name: Grade 3 Cranial Nerve XI Intra-Operative Injury, CTCAE


name: Grade 4 Stomach Mucositis or Stomatitis by Clinical Examination Classification, CTCAE


name: Grade 3 Oral Cavity NOS Intra-Operative Injury, CTCAE


name: Breast Cancer pTis (LCIS) TNM Finding v6 and v7

description: Breast cancer with a finding of lobular carcinoma in situ. (from AJCC 6th and 7th Ed.)


name: Adult Acute Myeloid Leukemia with t(16;16)(p13.1;q22); CBFB-MYH11

description: An acute myeloid leukemia with t(16;16)(p13.1;q22); CBFB-MYH11 occurring in adults.


Stage IV Bone Cancer AJCC v8

description: Stage IV includes: IVA: (Any T, N0, M1a, Any G); IVB: (Any T, N1, Any M, Any G); (Any T, Any N, M1b, Any G). N0: No regional lymph node metastasis. N1: Regional lymph node metastasis. M1a: Metastasis in the lung. M1b: Metastasis in the bone or other distant sites. (AJCC 8th ed.)


name: Juvenile rheumatoid arthritis with systemic onset of other specified site

description: Evidence of juvenile rheumatoid arthritis with systemic onset in another specified site.


25-Hydroxyvitamin D Less than 32 ng/ml

description: A semiquantitative finding indicating that the concentration of 25-hydroxyvitamin D2 plus 25-hydroxyvitamin D3 is less than 32 ng/mL.


name: Mycosis fungoides involving lymph nodes of head, face, and neck

description: Evidence of mycosis fungoides, lymph nodes of head, face, and neck.


name: Unspecified Atherosclerosis of Other Type of Bypass Graft(s) of the Extremities, Unspecified Extremity

description: Evidence of unspecified atherosclerosis of other type of bypass graft(s) of the extremities in an unspecified extremity.


name: Breast Cancer Pathologic Regional Lymph Nodes TNM Finding v7

description: A pathologic finding about one or more characteristics of breast cancer, following the rules of the TNM AJCC v7 classification system as they pertain to staging of regional lymph nodes.  The classification is based on axillary lymph node dissection with or without sentinel lymph node biopsy. (partially adapted from AJCC 7th Ed.)


name: Grade 3 Rectum Mucositis or Stomatitis by Clinical Examination Classification, CTCAE


name: Larynx Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


Grade 1 Infant Irritability, AE

description: An adverse event in a newborn characterized by mild, self-limiting, irritability, not affecting feeding and sleeping.


name: Grade 3 Salivary Gland Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


Grade 1 Hemorrhoids, CTCAE

description: Asymptomatic; clinical or diagnostic observations only; intervention not indicated


name: Unspecified Malignant Neoplasm of Overlapping Sites of Skin

description: Evidence of unspecified malignant neoplasm of overlapping sites of skin.


name: Grade 2 Cecum Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


name: Grade 5 Bronchopulmonary Hemorrhage, CTCAE

description: Death


name: Recovered from Adverse Event with Sequelae

description: One of the possible results of an adverse event outcome where the subject recuperated but retained pathological conditions resulting from the prior disease or injury.


name: Malignant Neoplasm of Short Bones of Left Upper Limb

description: Evidence of a malignant neoplasm of the short bones of left upper limb.


Disorder of transplanted kidney

description: A disease or disorder that is associated with a transplanted kidney.


name: Grade 3 Urinary Electrolyte Wasting, CTCAE


name: Stage IA Pancreatic Cancer AJCC v6 and v7

description: Stage IA includes: T1, N0, M0. T1: Tumor limited to the pancreas, 2 cm or less in greatest dimension.  N0: No regional lymph node metastasis.  M0: No distant metastasis. (from AJCC 7th Ed.)


Benzene Exposure

description: Environmental, occupational or consumer-based exposure to benzene, benzene-containing compounds or benzene derivatives.


name: Thyroid Cancer Pathologic Regional Lymph Nodes TNM Finding v6

description: A pathologic finding about one or more characteristics of thyroid cancer, following the rules of the TNM AJCC v6 classification system as they pertain to staging of regional lymph nodes. TNM pathologic regional lymph nodes findings are based on clinical findings supplemented by histopathologic examination of one or more tissue specimens acquired during surgery.


name: Recurrent Endometrial Mixed Cell Adenocarcinoma

description: The reemergence of endometrial mixed cell adenocarcinoma after a period of remission.


name: Follicular Lymphoma Grade I, Lymph Nodes of Multiple Sites

description: Evidence of follicular lymphoma grade I in the lymph nodes of multiple sites.


Decreased Drug Level

description: A reduction in the expected therapeutic effect of a drug due to increased clearance.


name: Refractory Malignant Nongerminomatous Germ Cell Tumor

description: Malignant nongerminomatous germ cell tumor that is resistant to treatment.


Non-response per Protocol

description: A response defined as a non-response in the protocol.


Adverse Event Severity Grade

description: A numeric value corresponding to the degree of severity of an adverse event.


name: Cerebral Infarction due to Unspecified Occlusion or Stenosis of Left Carotid Artery

description: Evidence of cerebral infarction due to an unspecified occlusion or stenosis of the left carotid artery.


name: Grade 3 Penis Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


name: Testicular Cancer Pathologic Primary Tumor TNM Finding v8

description: A pathologic finding about one or more characteristics of testicular cancer, following the rules of the TNM AJCC v8 classification system as they pertain to staging of the primary tumor.


Carcinoma in situ of ampulla of Vater

description: Stage 0 includes: Tis, N0, M0.  Tis: Carcinoma in situ.  N0: No regional lymph node metastasis.  M0: No distant metastasis. (from AJCC 7th Ed.)


Grade 3 Hepatitis B Reactivation, CTCAE

description: Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; IV intervention indicated


name: Other Sequelae following Unspecified Cerebrovascular Disease

description: Evidence of other sequelae following unspecified cerebrovascular disease not specified elsewhere.


name: Juvenile Arthritis, Unspecified, Left Elbow

description: Evidence of juvenile arthritis in the unspecified in the left elbow.


Breast Cancer pN3a TNM Finding v8

description: Breast cancer with metastases in 10 or more axillary lymph nodes (at least one tumor deposit larger than 2.0 mm); or metastases to the infraclavicular (level III axillary) lymph nodes. (from AJCC 8th Ed.)


name: Grade 3 Sciatic Nerve Intra-Operative Injury, CTCAE


Poorly Differentiated Fibrosarcoma

description: A usually aggressive malignant neoplasm arising from the deep soft tissue.  It is characterized by the presence of poorly-differentiated spindle-shaped fibroblasts, collagenous stroma formation and increased mitotic activity.


name: Cerebral Infarction due to Unspecified Occlusion or Stenosis of Right Post Cerebral Artery

description: Evidence of cerebral infarction due to an unspecified occlusion or stenosis of the right post cerebral artery.


name: Overlapping malignant neoplasm of tonsil

description: Evidence of a malignant neoplasm of overlapping sites of the tonsil.


name: Type 1 Diabetes Mellitus with Proliferative Diabetic Retinopathy with Macular Edema, Unspecified Eye

description: Evidence of type 1 diabetes mellitus with proliferative diabetic retinopathy with macular edema in an unspecified eye.


name: Grade 5 Gallbladder Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


Seasickness

description: A sensation of discomfort associated with travel over water, which may include nausea, vomiting, dizziness, or sweating.


name: Grade 1 Urethra Intra-Operative Injury, CTCAE


name: Conjunctival Melanoma pT1b TNM Finding v8

description: Conjunctival melanoma with tumor of the bulbar conjunctiva invading the substantia propria, more than 2.0 mm in thickness. (from AJCC 8th Ed.)


Nail Infection, CTCAE

description: A disorder characterized by an infectious process involving the nail.


name: Grade 2 Dental-Tooth Infection with Unknown Absolute Neutrophil Count, CTCAE


Urethral Condyloma Acuminatum

description: A sexually transmitted papillary neoplasm that arises from the epithelial surface of the urethra, and caused by the human papillomavirus.


name: Merkel Cell Carcinoma Clinical Regional Lymph Nodes TNM Finding v8

description: A clinical finding about one or more characteristics of Merkel cell carcinoma, following the rules of the TNM AJCC v8 classification system as they pertain to staging of regional lymph nodes.


Acquired Factor I Deficiency

description: An acquired coagulation disorder characterized by the partial or complete absence of fibrinogen (factor I) activity in the blood.


Environmental or Occupational Exposure

description: The exposure to potentially harmful agents in the environment or to work-related environmental factors.


Body Temperature Associated Symptom

description: An alteration in body temperature outside the normal range.


Peritoneal Inclusion Cyst

description: A cyst that is located in the peritoneum and is lined by benign mesothelium.


name: Atherosclerosis of Native Arteries of Extremity with Rest Pain, Unspecified Extremity

description: Evidence of atherosclerosis of native arteries of extremity with rest pain, unspecified extremity.


Elevated Erythropoietin

description: A finding indicating elevated concentrations of erythropoietin in blood.


name: Grade 4 Skin Intra-Operative Injury, CTCAE


name: cocaine dependence with intoxication - uncomplicated

description: Evidence of cocaine dependence with intoxication, uncomplicated.


Compound Spitz Nevus

description: A Spitz nevus characterized by the presence of both junctional and dermal melanocytic components.


Esophageal Cancer by AJCC v6 Stage

description: A term that refers to the staging of esophageal carcinoma according to the American Joint Committee on Cancer, 6th edition.


Well Differentiated Fibrosarcoma

description: A well-differentiated malignant neoplasm arising from the deep soft tissues.  It is characterized by the presence of spindle-shaped fibroblasts and collagenous stroma formation in a herringbone growth pattern.


CD34 Negative

description: An indication that expression of CD34 has not been detected in a sample.


Diplegia

description: Paralysis affecting corresponding parts on both sides of the body.


Refractory Endometrial Adenocarcinoma

description: Endometrial adenocarcinoma that is resistant to treatment.


Luminal B Prostate Carcinoma

description: Prostate carcinoma associated with increased androgen receptor expression and signaling (androgen activity pathway), increased luminal markers, and a higher proliferation score than the luminal A prostate carcinoma. Patients with luminal B prostate carcinoma have the poorest prognosis but respond better to postoperative androgen deprivation therapy compared to patients with non-luminal B prostate carcinoma.


name: Appendix Neuroendocrine Tumor pT1 TNM Finding v8

description: Appendix neuroendocrine tumor measuring 2 cm or less in greatest dimension. (from AJCC 8th Ed.)


Other Juvenile Arthritis, Right Wrist

description: Evidence of other juvenile arthritis in the right wrist not specified elsewhere.


name: Grade 5 Small Bowel Infection NOS with Unknown Absolute Neutrophil Count, CTCAE


Intentional Trauma

description: An injury that is not the result of an accident or natural causes.


Grade 2 Hypocalcemia, CTCAE

description: Corrected serum calcium of <8.0-7.0 mg/dL; <2.0-1.75 mmol/L; Ionized calcium <1.0-0.9 mmol/L; symptomatic


Toxic methemoglobinemia with cyanosis

description: Blue skin coloration due to elevated blood levels of methemoglobin. The degree of cyanosis is directly correlated to the concentration of methemoglobin in the blood. As methemoglobin is not suitable for carrying oxygen, hypoxemia becomes a serious sequela.


Grade 2 Vaginal Perforation, CTCAE

description: Invasive intervention not indicated


name: Metastatic Malignant Pancreatic Neoplasm

description: A malignant neoplasm that arises from the pancreas and has metastasized to another anatomic site.


name: Cerebral Infarction due to Unspecified Occlusion or Stenosis of Unspecified Post Cerebral Artery

description: Evidence of cerebral infarction due to an unspecified occlusion or stenosis of an unspecified post cerebral artery.


name: Atherosclerosis of Other Type of Bypass Graft(s) of the Extremities with Rest Pain, Bilateral Legs

description: Evidence of atherosclerosis of other type of bypass graft(s) of the extremities with rest pain in both legs.


name: Other Specified Diabetes Mellitus with Proliferative Diabetic Retinopathy with Combined Traction Retinal Detachment and Rhegmatogenous Retinal Detachment, Bilateral

description: Evidence of other specified diabetes mellitus with proliferative diabetic retinopathy with combined traction retinal detachment and rhegmatogenous retinal detachment that is bilateral not specified elsewhere.


name: Grade 3 Other Hepatobiliary and Pancreas, CTCAE


name: Grade 2 Intraoperative Renal Injury, CTCAE

description: Partial resection of injured organ/structure indicated


Decreased anogenital distance

description: An indication that the anogenital distance is less than the norm.


Edge or Boundary Artifact

description: An artifact that occurs where different tissues meet.


Tracheitis, CTCAE

description: A disorder characterized by an infectious process involving the trachea.


Grilling Smoke Exposure

description: Environmental, occupational or consumer-based exposure to airborne gases and particulates emitted by an indoor or outdoor grill used for cooking.


name: Exocrine Pancreatic Cancer pN1a TNM Finding

description: Exocrine pancreatic cancer with metastasis to a single regional lymph node. (from CAP Cancer of the Endocrine Pancreas Protocol- January 2005 Revision)


name: Other nonrheumatic tricuspid valve disorders

description: Evidence of other non-rheumatic tricuspid valve disorders not specified elsewhere.


name: Colon or Rectum Neuroendocrine Tumor pT1b TNM Finding v7

description: Colon or rectum neuroendocrine tumor invading lamina propria or submucosa and is 1-2 cm in greatest dimension. (from AJCC 7th Ed.)


description: Evidence of alcohol abuse with withdrawal with perceptual disturbance.


Pancreatic adenocarcinoma recurrent

description: The reemergence of pancreatic adenocarcinoma after a period of remission.


Generalized Edema, CTCAE

description: A disorder characterized by fluid accumulation in the tissues of the body including the skin.


HBV Genotype Finding

description: The determination of the genotype of hepatitis b virus in a blood sample.


Bronchopulmonary Dysplasia, AE

description: An adverse event in a newborn characterized by a lung disorder associated with pulmonary maldevelopment, scarring, and/or inflammation that develops in preterm neonates. The condition is defined based on treatment with supplemental oxygen for at least 28 days adjusted for the degree of prematurity.


Peritoneal and Retroperitoneal Neoplasm

description: A benign or malignant, primary or metastatic neoplasm that affects the peritoneum and/or retroperitoneum.


name: Grade 5 Thorax Soft Tissue Necrosis, CTCAE


name: Duodenum and Ampulla of Vater Neuroendocrine Tumor pM1b TNM Finding v8

description: Duodenum and ampulla of Vater neuroendocrine tumor with metastasis in at least one extrahepatic site (e.g., lung, ovary, nonregional lymph node, peritoneum, bone). (from AJCC 8th Ed.)


name: Cannabis Use, Unspecified with Psychotic Disorder, Unspecified

description: Evidence of cannabis use, unspecified with psychotic disorder.


name: Grade 2 Joint Intra-Operative Injury, CTCAE


name: Other Specified Type of Carcinoma in Situ of Breast

description: Evidence of other specified type of carcinoma in situ of the breast not specified elsewhere.


name: Hodgkin's disease nodular sclerosis stage I subdiaphragmatic


Grade 2 Pancreatitis, CTCAE

description: Enzyme elevation; radiologic findings only


Grade 3 Stevens-Johnson Syndrome, CTCAE

description: Skin sloughing covering <10% BSA with associated signs (e.g., erythema, purpura, epidermal detachment, and mucous membrane detachment)


Venous Injury, CTCAE

description: A finding of damage to a vein.


name: Type 2 diabetes mellitus with hypoglycemia with coma

description: Evidence of type 2 diabetes mellitus with hypoglycemia with coma.


name: Supraglottic Cancer pN2b TNM Finding v6 and v7

description: Supraglottic cancer with metastasis in two or more ipsilateral nodes, none more than 6 cm in greatest dimension. (from AJCC 6th and 7th Eds.)


name: Major Salivary Gland Cancer pT3 TNM Finding v8

description: Major salivary gland cancer with tumor more than 4 cm in greatest dimension, and/or tumor having extraparenchymal extension. Extraparenchymal extension is clinical or macroscopic evidence of invasion of soft tissues. Microscopic evidence alone does not constitute extraparenchymal extension for classification purposes. (from AJCC 8th Ed.)


name: Grade 2 Uterus Stricture or Stenosis, CTCAE


name: Nodular Sclerosis Classic Hodgkin Lymphoma, Lymph Nodes of Axilla and Upper Limb

description: Evidence of nodular sclerosis classic Hodgkin lymphoma in the lymph nodes of axilla and upper limb.


Difficult Vascular Access

description: Access to the subject's vasculature is troublesome or formidable. (ACC)


name: acute myeloid leukemia with inv(3) (q21.3;q26.2) or t(3;3) (q21.3;q26.2)

description: An acute myeloid leukemia associated with inv(3)(q21.3q26.2) or t(3;3)(q21.3;q26.2) resulting in the reposition of a distal GATA2 enhancer to activate MECOM expression. It may present de novo or follow a myelodysplastic syndrome. The clinical course is aggressive.


Laryngeal Cancer pN3 TNM Finding v8

description: Laryngeal cancer with metastasis in a lymph node, more than 6 cm in greatest dimension and ENE(-); or metastasis in a single ipsilateral lymph node, more than 3 cm in greatest dimension and ENE(+); or metastases in multiple ipsilateral, contralateral, or bilateral lymph nodes and any with ENE(+). (from AJCC 8th Ed.)


External Ear Pain, CTCAE 5.0

description: A disorder characterized by a sensation of marked discomfort in the external ear region.


Grade 1 Psychosis, CTCAE

description: Mild psychotic symptoms


name: Clinical Stage 0 Esophageal Adenocarcinoma AJCC v8

description: Stage 0 includes: Tis, N0, M0. Tis: High-grade dysplasia, defined as malignant cells confined to the epithelium by the basement membrane. N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 8th ed.)


name: Upper Airway Infection with Unknown Absolute Neutrophil Count NOS, CTCAE


Hyponatremia, CTCAE

description: A disorder characterized by laboratory test results that indicate a low concentration of sodium in the blood.


Grade 5 Urethral Infection, CTCAE

description: Death


name: Grade 3 Middle Ear Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


Psoriatic Juvenile Idiopathic Arthritis

description: A category of juvenile idiopathic arthritis defined by the presence of arthritis with a personal or family history of psoriasis, and features such as dactylitis and nail dystrophy.


name: Pancreatic Neuroendocrine Tumor pN0 TNM Finding v8

description: Pancreatic neuroendocrine tumor without regional lymph node involvement. (from AJCC 8th Ed.)


Hepatic Thrombosis

description: Formation of a blood clot (thrombus) in the lumen of the veins in the liver or hepatic artery.


Grade 5 Sinusitis, CTCAE

description: Death


Non-traumatic subdural hemorrhage

description: Evidence of nontraumatic subdural hemorrhage.


Glottic Cancer pT3 TNM Finding v8

description: Glottic cancer with tumor limited to the larynx with vocal cord fixation and /or invasion of paraglottic space, and/or inner cortex of the thyroid cartilage. (from AJCC 8th Ed.)


Biliary Anastomotic Leak, CTCAE

description: A finding of leakage of bile due to breakdown of a biliary anastomosis (surgical connection of two separate anatomic structures).


name: arthropathy following intestinal bypass vertebrae

description: Evidence of arthropathy following intestinal bypass in the vertebrae.


name: Enteropathic Arthropathies, Unspecified Hand

description: Evidence of enteropathic arthropathies in an unspecified hand.


Grade 1 Neonatal Diarrhea, AE

description: An adverse event in a newborn characterized by an increase of 2-4 stools per day over baseline; mild increase in ostomy output compared to baseline.


name: Drug or Chemical Induced Diabetes Mellitus with Unspecified Diabetic Retinopathy without Macular Edema

description: Evidence of drug or chemical induced diabetes mellitus with unspecified diabetic retinopathy without macular edema.


name: Liver Cancer Pathologic Regional Lymph Nodes TNM Finding v7

description: A pathologic finding about one or more characteristics of liver cancer, following the rules of the TNM AJCC v7 classification system as they pertain to staging of regional lymph nodes.


T2 Hypointensity Brainstem

description: Areas of focal dark T2 signal (hypointense to cerebellar gray matter), not representing infiltrated normal internal brainstem structures. These areas may typically exhibit relative diffusions restriction and/or enhancement.


Non-Neoplastic Soft Tissue Disorder

description: A non-neoplastic disorder that affects the soft tissue.


Pleural Mesothelioma pT2 TNM Finding v7

description: Pleural mesothelioma with a tumor involving each of the ipsilateral pleural surfaces (parietal, mediastinal, diaphragmatic, and visceral pleura) with at least one of the following: involvement of diaphragmatic muscle; extension of tumor from visceral pleura into the underlying pulmonary parenchyma. (from AJCC 7th Ed.)


Intraoperative Endocrine Injury, CTCAE

description: A finding of damage to the endocrine gland during a surgical procedure.


Grade 4 Duodenal Obstruction, CTCAE

description: Life-threatening consequences; urgent operative intervention indicated


Grade 2 Intracranial Hemorrhage, CTCAE

description: Moderate symptoms; intervention indicated


Hyperplasia of pituitary gland

description: A rare condition characterized by hyperplasia and hypertrophy of the pituitary gland. It is caused by hypersecretion of hypothalamic stimulating hormones.


Recurrent Malignant Skin Neoplasm

description: Reemergence of a malignant skin neoplasm after a period of remission.


name: Grade 5 Vascular Disorders - Other, Specify, CTCAE

description: Death


Recurrent Malignant Scrotal Neoplasm

description: The reemergence of a malignant scrotal neoplasm after a period of remission.


Grade 1 Hypophysitis, CTCAE

description: Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated


name: Metastatic malignant neoplasm to esophagus

description: A malignant neoplasm that has spread to the esophagus from another organ or system, or from another primary esophageal tumor. The primary esophageal tumor is not in continuity with the metastatic lesion. Representative examples of metastatic cancers to the esophagus include breast and lung metastatic carcinomas and melanomas.


Pathologic TNM Finding

description: A TNM finding obtained following the microscopic examination of a specimen.


Grade 4 Rash Acneiform, CTCAE

description: Life-threatening consequences; papules and/or pustules covering any % BSA, which may or may not be associated with symptoms of pruritus or tenderness and are associated with extensive superinfection with IV antibiotics indicated


name: Lip and Oral Cavity Cancer cM1 TNM Finding v8

description: Lip and oral cavity cancer with distant metastasis. (from AJCC 8th Ed.)


cell-associated neurotoxicity

description: Neurotoxicity associated with immune effector cell therapy. It may be characterized by aphasia, altered level of consciousness, motor weakness, seizures, and cerebral edema.


Grade 1 Personality Change, CTCAE

description: Mild personality change


Grade 5 Atelectasis, CTCAE

description: Death


name: Soft Tissue Sarcoma of the Head and Neck Pathologic Distant Metastasis TNM Finding v8

description: A pathologic finding about one or more characteristics of soft tissue sarcoma of the head and neck, following the rules of the TNM AJCC v8 classification system as they pertain to distant metastases.


malignant neoplasm of right ovary

description: Evidence of a malignant neoplasm of the right ovary.


name: Post-Dysenteric Arthropathy, Right Wrist

description: Evidence of post-dysenteric arthropathy in the right wrist.


Dissection of artery of upper extremity

description: Evidence of dissection of artery of upper extremity.


name: Platelet Count Greater Than or Equal to 150x10^9/L

description: A semiquantitative hemocytometry finding indicating the presence of least 150 billion platelets per liter of blood.


name: rheumatoid vasculitis with rheumatoid arthritis of hand

description: Evidence of rheumatoid vasculitis with rheumatoid arthritis of unspecified hand.


name: Grade 4 Eye Infection NOS with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


Other hereditary ataxias

description: Evidence of other hereditary ataxias not specified elsewhere.


Recurrent Visual Pathway Glioma

description: The reemergence of visual pathway glioma after a period of remission.


Breast Cancer cM1 TNM Finding v6

description: Breast cancer with distant metastasis. (from AJCC 6th Ed.)


name: Grade 4 Appendix Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


name: Grade 3 Kidney Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


Grade 2 Ischemia Cerebrovascular, CTCAE

description: Moderate symptoms


2-Hour Postprandial Insulin

description: The amount of insulin present in a sample two hours after a subject has eaten a meal.


Grade 1 Periodontal Disease, CTCAE

description: Gingival recession or gingivitis; limited bleeding on probing; mild local bone loss


name: Nasal Cavity and Ethmoid Sinus Cancer Pathologic TNM Finding v7

description: A pathologic finding about one or more characteristics of nasal cavity and ethmoid sinus cancer, following the rules of the TNM AJCC v7 classification system.  The pathologic staging requires the use of all information obtained in clinical staging and in histologic study of the surgically resected specimens.  The surgeon's evaluation of gross unresected residual tumor must also be included.  (from AJCC 7th Ed.)


HER2/Neu Low Expression

description: An immunohistochemical result indicating that HER2/Neu (ERBB2) is expressed at low levels in a sample.


Grade 2 Wound Infection, CTCAE

description: Oral intervention indicated (e.g., antibiotic, antifungal, or antiviral)


Grade 4 Esophageal Infection, CTCAE

description: Life-threatening consequences; urgent intervention indicated


name: Gallbladder Cancer Pathologic Distant Metastasis TNM Finding v7

description: A pathologic finding about one or more characteristics of gallbladder cancer, following the rules of the TNM AJCC v7 classification system as they pertain to distant metastases.  There is no pathologic M0 for gallbladder cancer.


name: Acute Myeloid Leukemia with ZRSR2 Mutation

description: An acute myeloid leukemia associated with ZRSR2 gene mutation.


Stage IIIB Prostate Cancer AJCC v8

description: Stage IIIB includes: T3-4, N0, M0, PSA: Any, Grade Group 1-4; T3: Prostate cancer with extraprostatic tumor that is not fixed or does not invade adjacent structures. T4: Prostate cancer in which the tumor is fixed or invades adjacent structures other than seminal vesicles such as external sphincter, rectum, bladder, levator muscles, and/or pelvic wall. N0: Prostate cancer with no positive regional nodes. M0: Prostate cancer without evidence of distant metastasis. Grade Group 1: Gleason Score 6 or less, Gleason Pattern 3 or less+3. Grade Group 2: Gleason Score 7, Gleason Pattern 3+4. Grade Group 3: Gleason Score 7, Gleason Pattern 4+3. Grade Group 4: Gleason Score 8, Gleason Pattern 4+4. (AJCC 8th ed.)


name: Locally Advanced Cervical Squamous Cell Carcinoma

description: Cervical squamous cell carcinoma that has spread from its original site of growth to nearby tissues or lymph nodes.


Undetectable PSA

description: An indication that the PSA level in a blood sample was not detected or below the detection limit.


name: Grade 4 Dental-Tooth Infection with Unknown Absolute Neutrophil Count, CTCAE


name: Rheumatoid Arthritis with Rheumatoid Factor of Other Specified Site without Organ or Systems Involvement

description: Evidence of rheumatoid arthritis with rheumatoid factor of other specified site without organ or systems involvement.


name: Direct Infection of Unspecified Wrist in Infectious and Parasitic Diseases Classified Elsewhere

description: Evidence of direct infection of unspecified wrist in infectious and parasitic diseases classified elsewhere.


name: Atherosclerosis of Other Type of Bypass Graft(s) of Extremities with Intermittent Claudication, Unspecified Extremity

description: Evidence of atherosclerosis of other type of bypass graft(s) of extremities with intermittent claudication in the unspecified extremity.


name: Colon or Rectum Neuroendocrine Tumor pM1 TNM Finding v7

description: Colon or rectum neuroendocrine tumor with distant metastasis. (from AJCC 7th Ed.)


Edema Trunk, CTCAE

description: A disorder characterized by swelling due to excessive fluid accumulation in the trunk area.


name: Cutaneous T Lymphoblastic Leukemia/Lymphoma

description: T-lymphoblastic leukemia/lymphoma that affects the skin.


name: Recurrent Endometrial Mucinous Adenocarcinoma

description: The reemergence of endometrial mucinous adenocarcinoma after a period of remission.


name: Malignant Carcinoid Tumor of the Small Intestine, Unspecified Portion

description: Evidence of a malignant carcinoid tumor of the small intestine, unspecified portion.


name: Invasive Pancreatic Micropapillary Adenocarcinoma

description: An invasive pancreatic ductal adenocarcinoma characterized by the presence of clusters of malignant cells located within artifactual clear stromal spaces.


Breast Cancer pMX TNM Finding v6

description: Breast cancer in which the status of distant metastasis cannot be assessed. (from AJCC 6th Ed.)


Kidney Cancer TNM Finding v7

description: A finding about one or more characteristics of kidney cancer, following the rules of the TNM AJCC v7 classification system.  Renal pelvis and ureter cancers are not included in this classification. (from AJCC 7th Ed.)


Grade 1 Akathisia, CTCAE

description: Mild restlessness or increased motor activity


Prostate Cancer pMX TNM Finding v6

description: Prostate cancer in which the status of distant metastasis cannot be assessed. (from AJCC 6th Ed.)


Subphrenic Abscess

description: An abscess that is located in the anatomical space between the diaphragm and the liver and/or spleen.


name: Acute Myeloid Leukemia with MECOM Rearrangement

description: Acute myeloid leukemia characterized by rearrangement of the MECOM gene with various genes.


name: Grade 2 Small Intestinal Anastomotic Leak, CTCAE

description: Symptomatic; medical intervention indicated


name: Grade 2 Cranial Nerve II Neuropathy, CTCAE


name: Thyrotoxicosis, Unspecified with Thyrotoxic Crisis or Storm

description: Evidence of thyrotoxicosis, unspecified with thyrotoxic crisis or storm.


name: Mucosal Melanoma of the Head and Neck Clinical Distant Metastasis TNM Finding v8

description: A clinical finding about one or more characteristics of mucosal melanoma of the head and neck, following the rules of the TNM AJCC v8 classification system as they pertain to distant metastases.


name: Grade 4 Vagina Infection with Unknown Absolute Neutrophil Count, CTCAE


Grade 3 Colonic Fistula, CTCAE

description: Invasive intervention indicated


name: Nodular Lymphocyte Predominant Hodgkin Lymphoma, Spleen

description: Evidence of nodular lymphocyte predominant Hodgkin lymphoma in the spleen.


Grade 2 GGT Increased, CTCAE

description: >2.5-5.0 x ULN if baseline was normal; >2.5-5.0 x baseline if baseline was abnormal


name: Testicular Cancer Clinical TNM Finding v7

description: A clinical finding about one or more characteristics of testicular cancer, following the rules of the TNM AJCC v7 classification system.


Stage III Cervical Cancer FIGO 2009

description: Cervical carcinoma involving lower vagina, pelvic sidewall, and ureters. (FIGO 2009)


name: Other Nontraumatic Subarachnoid Hemorrhage

description: Evidence of other nontraumatic subarachnoid hemorrhage not specified elsewhere.


Insomnia exacerbated

description: Insomnia that is made worse by other factors, including pain, physiological or psychological disorders, external causes, or pharmacologic interventions.


name: Cutaneous Melanoma cM1a(0) TNM Finding v8

description: Cutaneous melanoma with distant metastasis to skin, soft tissue including muscle, and/or nonregional lymph node. LDH level not elevated. (from AJCC 8th Ed.)


Grade 5 Apnea, CTCAE

description: Death


name: Recurrent Digestive System Neuroendocrine Carcinoma

description: The reemergence of a neuroendocrine carcinoma in any part of the digestive system after a period of remission.


Post-Traumatic Hydrocephalus

description: Evidence of post-traumatic hydrocephalus.


name: Clonal Cytopenia of Undetermined Significance

description: Clinically meaningful cytopenia in one or more hematopoietic cell lineages. Clonal hematopoiesis is present with the variant allele frequency (VAF) equal or more that 2 percent. There is no other evidence of hematologic malignancy.


name: Ampulla of Vater Cancer cM0 TNM Finding v7

description: Ampulla of Vater cancer without evidence of distant metastasis. (from AJCC 7th Ed.)


Stage IB2 Cervical Cancer AJCC v9

description: Stage IB2 includes: T1b2, N0, M0. T1b2: Tumor measuring more than 2 cm and equal or less than 4 cm in greatest dimension. N0: No regional lymph node metastasis. M0: No distant metastasis. (from AJCC 9th Ed.)


name: Post-Procedural Heart Failure following Other Surgery

description: Evidence of post-procedural heart failure following other surgery.


name: Choroidal and Ciliary Body Melanoma pT2a TNM Finding v8

description: Choroidal and ciliary body melanoma, tumor size category 2 without ciliary body involvement and extraocular extension. (from AJCC 8th Ed.)


Retinoblastoma pM1 TNM Finding v8

description: Retinoblastoma with distant metastasis with microscopic confirmation. (from AJCC 8th Ed.)


name: Colorectal Cancer Pathologic Distant Metastasis TNM Finding v8

description: A pathologic finding about one or more characteristics of colorectal cancer, following the rules of the TNM AJCC v8 classification system as they pertain to distant metastases.


Cutaneous Melanoma pT0 TNM Finding v8

description: Cutaneous melanoma with no evidence of primary tumor (e.g., unknown primary or completely regressed melanoma). Thickness: Not applicable. Ulceration status: Not applicable. (from AJCC 8th Ed.)


name: Malignant Neoplasm of Overlapping Sites of Unspecified Bronchus and Lung

description: Evidence of a malignant neoplasm of overlapping sites of unspecified bronchus and lung.


Grade 1 Rash Maculo-Papular, CTCAE

description: Macules/papules covering <10% BSA with or without symptoms (e.g., pruritus, burning, tightness)


name: Malnutrition in Pregnancy, First Trimester

description: Evidence of malnutrition in pregnancy in the first trimester.


Sickening Pain

description: A sensation of discomfort or distress that makes the individual queasy or nauseated.


Grade 2 Skin Atrophy, CTCAE

description: Covering 10-30% BSA; associated with striae or adnexal structure loss


name: Major Salivary Gland Cancer Clinical Distant Metastasis TNM Finding v7

description: A clinical finding about one or more characteristics of major salivary gland cancer, following the rules of the TNM AJCC v7 classification system as they pertain to distant metastases.


name: Prostatic Urethra Cancer pT2 TNM Finding v8

description: Urethral cancer with tumor invading the prostatic stroma surrounding ducts either by direct extension from the urothelial surface or by invasion from prostatic ducts. (from AJCC 8th Ed.)


name: Monoplegia of Lower Limb following Non-Traumatic Intracerebral Hemorrhage Affecting Right Dominant Side

description: Evidence of monoplegia of lower limb following non-traumatic intracerebral hemorrhage affecting right dominant side.


name: Chronic combined systolic and diastolic heart failure

description: Chronic heart failure due to reduced contractility of the left ventricle and which does not fill properly due to decreased compliance.


Grade 3 Budd-Chiari Syndrome, CTCAE

description: Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; asterixis; mild encephalopathy


name: Nasopharyngeal Cancer Pathologic Primary Tumor TNM Finding v6

description: A pathologic finding about one or more characteristics of nasopharyngeal cancer, following the rules of the TNM AJCC v6 classification system as they pertain to staging of the primary tumor.


name: Locally Advanced Appendix Adenocarcinoma

description: Appendix adenocarcinoma that has spread from its original site of growth to nearby tissues or lymph nodes.


name: Grade 2 Neonatal Respiratory Insufficiency, AE

description: An adverse event in a newborn characterized by clinical evidence of increased respiratory distress without significant deterioration in gas exchange (increase in partial pressure of carbon dioxide (pCO2) or decrease in oxygenation); corrected by minor adjustments in current ventilatory support, supplemental oxygen or non-invasive support.


name: Thyroid Cancer Pathologic Regional Lymph Nodes TNM Finding v7

description: A pathologic finding about one or more characteristics of thyroid cancer, following the rules of the TNM AJCC v7 classification system as they pertain to staging of regional lymph nodes.


pN1 TNM Finding

description: A pathologic regional lymph node TNM finding. The definition of pN1 finding depends on the particular type of cancer that it refers to; for example, for breast cancer, pN1 finding is defined as follows: cancer with micrometastases (approximately 200 cells, larger than 0.2 mm, but none larger than 2.0 mm). (from AJCC 8th Ed.)


name: Jejunum Infection with Unknown Absolute Neutrophil Count, CTCAE


name: oligoarticular juvenile idiopathic arthritis of elbow

description: Evidence of pauciarticular juvenile rheumatoid arthritis in an unspecified elbow.


PSA Level 0.2 to Four

description: A blood concentration of prostate specific antigen between 0.2 ng/mL and 4 ng/mL.


description: Evidence of rheumatoid vasculitis with rheumatoid arthritis of multiple sites.


name: Grade 5 Restrictive Cardiomyopathy, CTCAE

description: Death


name: Refractory HIV-Related Lymphoproliferative Disorder

description: HIV-associated lymphoproliferative disorder that is resistant to treatment.


Refractory Barrett Esophagus

description: Dysplasia in Barrett esophagus that is resistant to treatment.


Prostatic Obstruction, CTCAE

description: A disorder characterized by compression of the urethra secondary to enlargement of the prostate gland. This results in voiding difficulties (straining to void, slow urine stream, and incomplete emptying of the bladder).


Eyelid Carcinoma pT2 TNM Finding v8

description: Eyelid carcinoma with tumor measuring more than 10 mm but 20 mm or less in greatest dimension. (from AJCC 8th Ed.)


Signal Transduction Alteration

description: Signal Transduction Alteration involves a change in the quality of existing cellular processes by which a cell propagates information from an extracellular signal through a series of biochemical reactions inside the cell to produce biological responses to events in the environment or internal milieu.


Constipation, CTCAE

description: A disorder characterized by irregular and infrequent or difficult evacuation of the bowels.


Advanced Merkel Cell Carcinoma

description: A Merkel cell carcinoma that has metastasized from its original site of growth to distal anatomic sites or is no longer responding to treatment.


name: Papillary, Follicular, Hurthle Cell, Poorly Differentiated, and Anaplastic Thyroid Carcinoma cN0b TNM Finding v8

description: No radiologic or clinical evidence of locoregional lymph node metastasis. (from AJCC 8th Ed.)


name: Grade 4 Cranial Nerve VIII Intra-Operative Injury, CTCAE


Intermediate Osteogenic Neoplasm

description: A non-metastasizing, locally aggressive, bone-forming neoplasm.


name: Merkel cell carcinoma of left eyelid, including canthus

description: Evidence of Merkel cell carcinoma of left eyelid including the canthus.


Paratesticular Epithelial Neoplasm

description: A benign, borderline, or malignant epithelial neoplasm that arises from the paratesticular structures.


name: Grade 5 Anus Mucositis or Stomatitis by Clinical Examination Classification, CTCAE


Arrhythmia Artifact

description: An imaging artifact resulting from a patient arrhythmia.


Lung Cancer pT1b TNM Finding v8

description: Lung cancer with tumor measuring more than 1 cm but 2 cm or less in greatest dimension. (from AJCC 8th Ed.)


Grade 5 Duodenal Infection, CTCAE

description: Death


name: Grade 1 Cranial Nerve Or Branch NOS Intra-Operative Injury, CTCAE


name: Malignant neoplasm of cerebrum (excluding lobes and ventricles)

description: Evidence of a malignant neoplasm of the cerebrum, except lobes and ventricles.


Dialysis dementia

description: A severe, often fatal encephalopathy which has been attributed to accumulation in the brain of aluminum from dialysate prepared with inadequately purified water.


name: Other Inflammatory Spondylopathies, Occipito-Atlanto-Axial Region

description: Evidence of other inflammatory spondylopathies in the occipito-atlanto-axial region not specified elsewhere.


name: Other Specified Diabetes Mellitus with Diabetic Autonomic Polyneuropathy

description: Evidence of other specified diabetes mellitus with diabetic autonomic polyneuropathy not specified elsewhere.


name: Soft Tissue Sarcoma of the Trunk and Extremities Pathologic Regional Lymph Nodes TNM Finding v8

description: A pathologic finding about one or more characteristics of soft tissue sarcoma of the trunk and extremities, following the rules of the TNM AJCC v8 classification system as they pertain to staging of regional lymph nodes.


name: Cutaneous Squamous Cell Carcinoma of the Head and Neck cN2 TNM Finding v8

description: Cutaneous squamous cell carcinoma of the head and neck with metastasis in a single ipsilateral lymph node larger than 3 cm but not larger than 6 cm in greatest dimension and ENE(-); or metastases in multiple ipsilateral lymph nodes, none larger than 6 cm in greatest dimension and ENE(-); or metastases in bilateral or contralateral lymph nodes, none larger than 6 cm in greatest dimension and ENE(-).  (from AJCC 8th Ed.)


name: Grade 5 Liver Infection with Unknown Absolute Neutrophil Count, CTCAE


name: Malignant Lymphoma, Large Cell, Cleaved and Non-Cleaved

description: Antiquated term describing follicular (nodular) or diffuse non-Hodgkin lymphomas that are composed of a mixture of large cells: large cleaved cells, with irregular nuclei without visible nucleoli; and large non-cleaved cells (centroblasts), having a rounder nucleus with two to three small, peripherally placed nucleoli and a small amount of basophilic cytoplasm.  The follicular variants represent mature B-cell lymphomas, whereas the diffuse variants can be either mature B- or mature T-cell lymphomas.


Acute hemorrhagic edema of infancy

description: A self-limiting cutaneous vasculitis that typically presents as a clinical triad of purpura, edema, and fever in children between the ages of four months and two years old. It is usually associated with a recent history of upper respiratory infection and/or antibiotic therapy.


description: A reactive cutaneous proliferation of macrophages associated with local trauma. It is characterized by the presence of giant cells with ground-glass cytoplasm. It presents as a single, asymptomatic, cutaneous or mucosal, firm xanthomatous to dark-red papule or nodule. (WHO 2018)


Low grade myofibroblastic sarcoma

description: A low-grade malignant neoplasm arising from the soft tissue and rarely bone. It is characterized by the presence of spindle-shaped myofibroblasts and collagenous stroma formation in a storiform growth pattern. Metastasis is very rare.


name: Lip and Oral Cavity Cancer pN2b TNM Finding v8

description: Lip and oral cavity cancer with metastases in multiple ipsilateral lymph nodes, none larger than 6 cm in greatest dimension and ENE(-). (from AJCC 8th Ed.)


name: Oropharyngeal (p16-Negative) Cancer pNX TNM Finding v8

description: Oropharyngeal (p16-negative) cancer in which the regional lymph nodes cannot be assessed. (from AJCC 8th Ed.)


Cutaneous Precursor Lymphoid Neoplasm

description: A precursor lymphoid neoplasm that affects the skin.


Tearing Chest Pain

description: The sensation of chest pain described as a sharp, lacerating, intense, discomfort; sometimes used to describe the pain felt during an aortic dissection.


Peritumoral Lesion

description: A lesion present in the area around a neoplasm.


Stage IIIA Cervical Cancer AJCC v9

description: Stage IIIA includes: T3a, N0, M0. T3a: Tumor involving the lower third of vagina but not extending to pelvic wall. N0: No regional lymph node metastasis. M0: No distant metastasis. (from AJCC 9th Ed.)


Adult Erythroleukemia

description: An erythroleukemia occurring in adults.


name: Other Juvenile Arthritis, Right Ankle and Foot

description: Evidence of other juvenile arthritis in the right ankle and foot not specified elsewhere.


Grade 1 Ileal Obstruction, CTCAE

description: Asymptomatic; clinical or diagnostic observations only; intervention not indicated


name: Conjunctival Carcinoma pN0 TNM Finding v8

description: Conjunctival carcinoma with no regional lymph node metastasis. (from AJCC 8th Ed.)


name: Other congenital malformations of aortic and mitral valves

description: Evidence of the other congenital malformations of the aortic and mitral valves not specified elsewhere.


name: Diabetes Mellitus due to Underlying Condition with Proliferative Diabetic Retinopathy with Combined Traction Retinal Detachment and Rhegmatogenous Retinal Detachment, Right Eye

description: Evidence of diabetes mellitus due to underlying condition with proliferative diabetic retinopathy with combined traction retinal detachment and rhegmatogenous retinal detachment in the right eye.


name: Unspecified Malignant Neoplasm of Skin of Other Part of Trunk

description: Evidence of unspecified malignant neoplasm of the skin of the other part of trunk.


name: Hypopharyngeal Cancer pN0 TNM Finding v8

description: Hypopharyngeal cancer with no metastasis to regional lymph nodes. (from AJCC 8th Ed.)


name: Mucosal Melanoma of the Head and Neck pT4b TNM Finding v7

description: Mucosal melanoma of the head and neck with very advanced disease.  Tumor involves brain, dura, skull base, lower cranial nerves (IX, X, XI, XII), masticator space, carotid artery, prevertebral space, or mediastinal structures. (from AJCC 7th Ed.)


name: Thyrotoxicosis with Toxic Single Thyroid Nodule without Thyrotoxic Crisis

description: Evidence of thyrotoxicosis with toxic single thyroid nodule without thyrotoxic crisis.


Lymphangioma of liver

description: A rare lymphangioma that arises from the liver.  It usually occurs in children and adolescents.


Distal Femur R1

description: The portion of the distal femur, identified during a DXA scan, that contains primarily metaphyseal or trabecular bone.


Grade 5 Esophagitis, CTCAE

description: Death


Bladder Cancer pN3 TNM Finding v7

description: Bladder cancer with metastasis to the common iliac lymph nodes. (from AJCC 7th Ed.)


Urinary Urgency, CTCAE

description: A disorder characterized by a sudden compelling urge to urinate.


name: Metastatic Childhood Astrocytoma by Toronto Guidelines v2

description: Distant metastases present. (Childhood cancer staging for population registries according to the Toronto Childhood Cancer Stage Guidelines - Version 2. Cancer Council Queensland and Cancer Australia: Brisbane, Australia; 2021.)


name: Vaginal Cancer Pathologic Primary Tumor TNM Finding v8

description: A pathologic finding about one or more characteristics of vaginal cancer, following the rules of the TNM AJCC v8 classification system as they pertain to staging of the primary tumor. The definitions of the T categories correspond to the stages accepted by FIGO. (from AJCC 8th Ed.)


name: Stage y-II Childhood Malignant Kidney Neoplasm Excluding Renal Cell Carcinoma by Toronto Guidelines v2, International Society of Pediatric Oncology (SIOP) Protocol

description: Tumor extends beyond kidney but completely resected. Tumor penetrates renal capsule into perirenal fat. Tumor infiltrates the renal sinus and/or invades blood and lymphatic vessels outside renal parenchyma but is completely resected. Tumor infiltrates adjacent organs or vena cava but is completely resected. (Childhood cancer staging for population registries according to the Toronto Childhood Cancer Stage Guidelines - Version 2. Cancer Council Queensland and Cancer Australia: Brisbane, Australia; 2021.)


T4e TNM Finding

description: A general term that refers to a TNM finding of a primary tumor with direct invasion of adjacent structures. The definition of T4e TNM finding depends on the specific type of cancer that it refers: for example, for choroidal and ciliary body melanoma it indicates any tumor size category with extraocular extension more than 5 mm in largest diameter.


name: Late Relapse of Acute Lymphoblastic Leukemia

description: Clinical and/or laboratory evidence of reemergence of acute lymphoblastic leukemia greater than or equal to 18 months (extramedullary) or 36 months (marrow) from diagnosis.


T3d TNM Finding

description: A TNM finding term that refers to choroidal and ciliary body melanoma, conjunctival melanoma, or retinoblastoma TNM staging. For choroidal and ciliary body melanoma it means tumor size category 3 with ciliary body involvement and extraocular extension 5 mm or less in largest diameter. For conjunctival melanoma it means tumor of any size invading the nasolacrimal duct and/or lacrimal sac and/or paranasal sinuses. For retinoblastoma it means hyphema and/or massive vitreous hemorrhage (clinical) or full-thickness invasion into the outer third of the sclera and/or invasion into or around emissary channels (pathologic). (from AJCC 8th Ed.)


name: Grade 4 Lip or Perioral Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


Metastatic sarcoma

description: A sarcoma that has spread from its original site of growth to another anatomic site.


name: Senile Degeneration of Brain NEC in NCI Thesaurus

description: Evidence of senile degeneration of brain, not elsewhere classified.


Multi-Organ Involvement

description: A finding indicating the spread of a neoplastic process to multiple organs.


Transition Zone of Prostate

description: The region of the prostate gland that is located deep to both the central and peripheral zones; it surrounds the proximal urethra, and is the zone of the prostate gland that grows throughout life, most often causing a condition called benign prostatic hypertrophy.


name: Lung Cancer Pathologic Primary Tumor TNM Finding v7

description: A pathologic finding about one or more characteristics of lung cancer, following the rules of the TNM AJCC v7 classification system as they pertain to staging of the primary tumor.


name: Mycosis Fungoides and Sezary Syndrome T1 TNM Finding v8

description: Limited patches, papules, and/or plaques covering less than 10% of the skin surface. Note: for skin, patch indicates any size skin lesion without significant elevation or induration. Presence/absence of hypo- or hyperpigmentation, scale, crusting, and/or poikiloderma should be noted. Plaque indicates any size skin lesion that is elevated or indurated. Presence or absence of scale, crusting, and/or poikiloderma should be noted. Histologic features such as folliculotropism, large-cell transformation (more than 25% large cells), and CD30 positivity or negativity, as well as clinical features such as ulceration are important to document. (from AJCC 8th Ed.)


Adverse Event by CTCAE Category

description: An adverse event as categorized by the Common Terminology Criteria for Adverse Events (CTCAE).


Grade 4 Jejunal Perforation, CTCAE

description: Life-threatening consequences; urgent operative intervention indicated


name: Grade 5 Liver Dysfunction or Failure by Clinical Classification, CTCAE


Vaginal Cancer pT3 TNM Finding v8

description: Vaginal cancer with tumor extending to the pelvic sidewall and/or involving the lower third of the vagina and/or causing hydronephrosis or nonfunctioning kidney. Pelvic sidewall is defined as the muscle, fascia, neurovascular structures, or skeletal portions of the bony pelvis. (from AJCC 8th Ed.)


name: Grade 4 Cranial Nerve Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


MET Exon 14 Skipping Mutation Negative

description: A genetic finding indicating that activating MET exon 14 skipping mutations have not been detected in a sample.


Grade 1 Euphoria, CTCAE

description: Mild mood elevation


name: Stage IIIB Ampulla of Vater Cancer AJCC v8

description: Stage IIIB includes: (T4, Any N, M0); (Any T, N2, M0). T4: Tumor involving the celiac axis, superior mesenteric artery, and/or common hepatic artery, irrespective of size. N2: Metastasis to four or more regional lymph nodes. M0: No distant metastasis. (AJCC 8th ed.)


Felty's Syndrome, Right Ankle and Foot

description: Evidence of Felty's syndrome in the right ankle and foot.


name: Stomach Mucositis or Stomatitis by Clinical Examination Classification, CTCAE


name: Conjunctival Melanoma pT4 TNM Finding v8

description: Conjunctival melanoma with tumor of any size invading the central nervous system. (from AJCC 8th Ed.)


name: Bladder Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


name: Grade 5 Stomach Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


name: Pleural Malignant Mesothelioma Clinical TNM Finding v8

description: A clinical finding about one or more characteristics of pleural malignant mesothelioma, following the rules of the TNM AJCC v8 classification system.


name: PSA Decline Greater than or Equal to 90 Percent

description: A finding indicating that the blood concentration of prostate specific antigen in a subject's sample has decreased by 90 percent or more when compared to the value recorded for a previous sample from that subject.


Gene Amplification Negative

description: An indication that amplification of one or more genes of interest was not detected in a sample.


name: Grade 4 Acute Vascular Leak Syndrome, CTCAE


name: Grade 1 Associated with Dentures or Dental Prosthesis, CTCAE


Stage IA1 Cervical Cancer FIGO 2009

description: Cervical carcinoma measuring equal or less than 3 mm in depth. (FIGO 2009)


NTRK1 Fusion Negative

description: An indication that the expression of a NTRK1 fusion has not been detected in a sample.


Unresectable Liposarcoma

description: A liposarcoma which is not amenable to surgical resection.


name: Grade 2 Skin Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


name: Stage II Ampulla of Vater Cancer AJCC v7

description: Stage II includes: IIA (T3, N0, M0); IIB (T1, N1, M0); (T2, N1, M0); (T3, N1, M0).  T3: Tumor invades the pancreas.  T1: Tumor limited to ampulla of Vater or sphincter of Oddi.  T2: Tumor invades the duodenal wall.  N0: No regional lymph node metastasis.  N1: Regional lymph node metastasis.  M0: No distant metastasis. (from AJCC 7th Ed.)


Teratoma with Endocrine Differentiation

description: A teratoma that arises outside an endocrine organ and shows endocrine differentiation. The endocrine component ranges from benign endocrine tissue to malignant endocrine neoplasms. This category includes struma ovarii, thyroid carcinoma arising in struma ovarii, and carcinoid tumor arising in ovarian teratoma.


name: Cardiac Failure due to Anesthesia During Pregnancy, Second Trimester

description: Evidence of cardiac failure due to anesthesia during pregnancy in the second trimester.


name: Human Immunodeficiency Virus Infection Complicating Childbirth

description: Evidence of human immunodeficiency virus infection complicating childbirth.


name: Nontraumatic Subarachnoid Hemorrhage from Anterior Communicating Artery

description: Evidence of nontraumatic subarachnoid hemorrhage from anterior communicating artery.


name: Sedative, Hypnotic or Anxiolytic Dependence with Mood Disorder

description: Evidence of sedative, hypnotic or anxiolytic dependence with mood disorder.


Grade 2 Wound Complication, CTCAE

description: Bedside local care indicated


Injury of adrenal gland

description: Trauma to the adrenal gland.


name: Gastrointestinal Anastomotic Leak, CTCAE

description: A finding of leakage due to breakdown of a gastrointestinal anastomosis (surgical connection of two separate anatomic structures).


name: Unspecified inflammatory spondylopathy, cervical region

description: Evidence of unspecified inflammatory spondylopathy in the cervical region.


name: T-Cell Prolymphocytic Leukemia, Small Cell Variant

description: A T-cell prolymphocytic leukemia characterized by the presence of small neoplastic prolymphocytes often with invisible nucleolus by light microscopy.


Advanced Anal Carcinoma

description: Anal carcinoma that has spread extensively to other anatomic sites or is no longer responding to treatment.


name: Mechanical Breakdown of Biological Heart Valve Graft, Initial

description: Evidence of mechanical breakdown of biological heart valve graft, initial.


name: Bipolar Disorder, Current Episode Mixed, Severe, with Psychotic Features

description: Evidence of bipolar disorder, current episode mixed, severe with psychotic features.


Refractory Myeloproliferative Neoplasm

description: A myeloproliferative neoplasm that does not respond to treatment.


name: IgM-Positive Primary Cutaneous Marginal Zone Lymphoproliferative Disorder

description: A primary cutaneous marginal zone lymphoproliferative disorder characterized by expression of IgM and absence of class-switched immunoglobulin heavy chain expression.


name: Prostate Cancer Pathologic TNM Finding v6

description: A pathologic finding about one or more characteristics of prostate cancer, following the rules of the TNM AJCC v6 classification system. TNM pathologic findings are based on clinical findings supplemented by histopathologic examination of one or more tissue specimens acquired during surgery.


Immune Dysregulation Disorder

description: A group of autoimmune disorders characterized by defects in self-tolerance (central or peripheral) resulting in autoimmune disease with or without recurrent infections, comprised by: Familial hemophagocytic lymphohistiocytosis (FHL) syndromes; FHL syndromes with hypopigmentation; Regulatory T cell (Treg) defects (eg, IPEX); Autoimmunity with or without lymphoproliferation (eg, autoimmune polyendocrinopathy with candidiasis and ectodermal dystrophy [APECED]); Autoimmune lymphoproliferative syndrome (ALPS); Immune dysregulation with colitis; and Susceptibility to Epstein-Barr virus (EBV) and lymphoproliferative conditions.


name: Grade 3 Neck Infection NOS with Unknown Absolute Neutrophil Count, CTCAE


name: Neoplasms Benign, Malignant and Unspecified (Incl Cysts and Polyps) - Other, Specify, CTCAE


Stage III Pancreatic Cancer AJCC v8

description: Stage III includes: (T1, N2, M0); (T2, N2, M0); (T3, N2, M0); (T4, Any N, M0). T1: Tumor measuring 2 cm or less in greatest dimension. T2: Tumor measuring more than 2 cm and 4 cm or less in greatest dimension. T3: Tumor measuring more than 4 cm in greatest dimension. T4: Tumor involving the celiac axis, superior mesenteric artery, and/or common hepatic artery, regardless of size. N2: Metastasis in four or more regional lymph nodes. M0: No distant metastasis. (AJCC 8th ed.)


Stage I Childhood Hodgkin Lymphoma

description: Ann Arbor Classification: Stage I: Involvement of a single lymph node region (I); or localized involvement of a single extralymphatic organ or site in the absence of any lymph node involvement (IE) (rare in Hodgkin lymphoma).


name: Frontal Lobe Anaplastic Oligodendroglioma

description: An anaplastic oligodendroglioma occurring in the frontal lobe.


name: Ann Arbor Stage II Supradiaphragmatic Hodgkin Lymphoma

description: Ann Arbor Classification: Stage II: Involvement of two or more lymph node regions on the superior side of the diaphragm (II) or localized involvement of a single associated extralymphatic organ or site and its regional lymph node(s) with or without involvement of other lymph node regions on the same side of the diaphragm (IIE). Note: The number of lymph node regions involved may be indicated by a subscript.


name: Wood-Burning Indoor Stove or Fireplace Smoke Exposure

description: Environmental or occupational exposure to airborne gases and particulates produced when wood is subjected to combustion in an indoor stove or fireplace.


name: Grade 4 Lymphatic Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


name: Follicular Lymphoma Grade III, Unspecified, Spleen

description: Evidence of unspecified follicular lymphoma grade III in the spleen.


Grade 1 Hepatic Hemorrhage, CTCAE

description: Mild symptoms; intervention not indicated


name: Carcinoma of the Lacrimal Gland pT3 TNM Finding v7

description: Carcinoma of the lacrimal gland with tumor measuring more than 4 cm in greatest dimension.  Note: As the maximum size of the lacrimal gland is 2 cm, T2 and greater tumors will usually extend into the orbital soft tissue.  (from AJCC 7th Ed.)


name: Mycosis fungoides of lymph nodes of multiple sites

description: Evidence of mycosis fungoides, lymph nodes of multiple sites.


name: Grade 2 Gallbladder Intra-Operative Injury, CTCAE


CD7 Negative

description: An indication that CD7 expression has not been detected in a sample.


name: oligoarticular juvenile idiopathic arthritis of hip

description: Evidence of pauciarticular juvenile rheumatoid arthritis in an unspecified hip.


Colorectal Cancer TNM Finding v7

description: A finding about one or more characteristics of colorectal cancer, following the rules of the TNM AJCC v7 classification system.  Sarcomas, lymphomas, and carcinoid tumors of the large intestine are not included in this classification. (from AJCC 7th Ed.)


name: Sonic Hedgehog/Patch Pathway Signaling Status Unknown

description: The result of the sonic hedgehog/patch pathway signaling status is not known or the test has not been performed.


name: Intraoperative Musculoskeletal Injury, CTCAE

description: A finding of damage to the musculoskeletal system during a surgical procedure.


description: A non-invasive neoplastic process that affects the epithelium of any part of the digestive system.  It is characterized by the presence of morphologic features of dysplasia (e.g., architectural and cytological epithelial alterations) or, in a minority of cases, lack of such morphologic features, as in colonic sessile serrated adenomas/polyps.


name: Intrahepatic Bile Duct Cancer Clinical TNM Finding v7

description: A clinical finding about one or more characteristics of intrahepatic bile duct cancer, following the rules of the TNM AJCC v7 classification system.  The clinical staging depends on imaging procedures.  (from AJCC 7th Ed.)


name: Prostatic Atypical Adenomatous Hyperplasia

description: A prostatic hyperplasia characterized by the presence of crowded adenomatous epithelial nodules.


Urethral Anastomotic Leak, CTCAE

description: A finding of leakage due to breakdown of a urethral anastomosis (surgical connection of two separate anatomic structures).


name: Lung Cancer Clinical Distant Metastasis TNM Finding v7

description: A clinical finding about one or more characteristics of lung cancer, following the rules of the TNM AJCC v7 classification system as they pertain to distant metastases.


name: Genitourinary malfunction arising from mental factors

description: A dysfunction in genitourinary function that is due to a psychological process.


Injury of urinary bladder

description: Trauma to the bladder.


name: Unspecified Juvenile Rheumatoid Arthritis, Unspecified Hip

description: Evidence of unspecified juvenile rheumatoid arthritis in an unspecified hip.


name: Grade 4 Large Bowel Mucositis or Stomatitis by Functional or Symptomatic Classification, CTCAE


Mixed acinar-ductal carcinoma

description: A carcinoma that arises from the pancreas showing either extensive mucin accumulation and acinar neoplastic cells or a mixture of columnar or signet-ring cells and acinar neoplastic cells.


name: Prostate Cancer pT2b TNM Finding v6 and v7

description: Prostate cancer involving more than one-half of one lobe, but not both lobes of the prostate gland. (from AJCC 6th and 7th Eds.)


Erythema toxicum neonatorum

description: A benign, self-limited eruption of vesicles, pustules, papules and macules seen in newborns. An eosinophilic infiltrate can be isolated suggesting an immune-mediated reaction in the skin.


name: Other Specified Diabetes Mellitus with Severe Nonproliferative Diabetic Retinopathy without Macular Edema, Left Eye

description: Evidence of other specified diabetes mellitus with severe nonproliferative diabetic retinopathy without macular edema in the left eye not specified elsewhere.


name: Other Atherosclerosis of Non-Autologous Biological Bypass Graft(s) of the Extremities, Other Extremity

description: Evidence of other atherosclerosis of non-autologous biological bypass graft(s) of the extremities, in the other extremity.


name: Grade 2 Liver Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


Gastric Adenoma, Gastric-Type

description: A neoplastic polyp that arises from the stomach.  It is characterized by the presence of gastric epithelial differentiation.  It includes pyloric gland adenomas and foveolar-type adenomas.


Tourettism

description: Tics that are secondary to an identifiable cause.


name: Fallopian Tube Cancer pT2a TNM Finding v7

description: Fallopian tube cancer with extension and/or metastasis to the uterus and/or ovaries. (from AJCC 7th Ed.)


name: Small Cell B-Cell Lymphoma, Lymph Nodes of Axilla and Upper Limb

description: Evidence of small cell B-cell lymphoma in the lymph nodes of axilla and upper limb.


name: Female Reproductive System Cancer TNM Finding v8

description: A finding about one or more characteristics of female reproductive system cancer, following the rules of the TNM AJCC v8 classification system. The TNM categories have been defined to correspond to the FIGO stages. Some amendments have been made in collaboration with FIGO, and the classifications now published have the approval of FIGO, AJCC, and all other national TNM committees of the Union for International Cancer Control (UICC). (from AJCC 8th Ed.)


name: Penis Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


name: Grade 1 Esophageal Varices Hemorrhage, CTCAE


Cervical Cancer cT3 TNM Finding v7

description: Cervical cancer extends to pelvic wall and/or involves lower third of vagina, and/or causes hydronephrosis or nonfunctioning kidney. (from AJCC 7th Ed.)


Jaccoud Arthropathy, Left Wrist

description: Evidence of Jaccoud arthropathy in the left wrist.


Gallbladder Cancer by AJCC v7 Stage

description: A term that refers to the staging of gallbladder cancer according to the American Joint Committee on Cancer, 7th edition.


name: Grade 5 Conjunctiva Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


Pulmonary Fistula

description: An abnormal communication between the lung and another organ or anatomic site.


Grade 2 Virilization, CTCAE

description: Moderate symptoms; medical intervention indicated


name: Other Specified Diabetes Mellitus with Diabetic Peripheral Angiopathy without Gangrene

description: Evidence of other specified diabetes mellitus with diabetic peripheral angiopathy without gangrene not specified elsewhere.


name: Appendiceal Carcinoid pT1a TNM Finding v7

description: Appendiceal carcinoid with tumor 1 cm or less in greatest dimension. (from AJCC 7th Ed.)


Grade 2 Somnolence, CTCAE

description: Moderate sedation; limiting instrumental ADL


Stage IV Uterine Corpus Cancer AJCC v8

description: Stage IV includes: IVA: T4, Any N, M0; IVB: Any T, Any N, M1. T4: Uterine corpus carcinoma or carcinosarcoma with tumor invading the bladder mucosa and/or bowel mucosa (bullous edema is not sufficient to classify a tumor as T4). M0: No distant metastasis. M1: Distant metastasis (includes metastasis to inguinal lymph nodes, intraperitoneal disease, lung, liver, or bone. It excludes metastasis to pelvic or para-aortic lymph nodes, vagina, uterine serosa, or adnexa). (from AJCC 8th Ed.)


Localized Sarcoma

description: A sarcoma that is confined to a specific site without evidence of spread to other anatomic sites.


Post-Dysenteric Arthropathy, Right Hip

description: Evidence of post-dysenteric arthropathy in the right hip.


name: Burkitt's tumor or lymphoma involving lymph nodes of head, face, and neck

description: Evidence of Burkitt lymphoma in the lymph nodes of head in the face in the and neck.


Grade 3 Biliary Fistula, CTCAE

description: Invasive intervention indicated


name: Grade 4 Cranial Nerve VII Motor Intra-Operative Injury, CTCAE


name: Hypopharyngeal Cancer pN2b TNM Finding v8

description: Hypopharyngeal cancer with metastases in multiple ipsilateral lymph nodes, none larger than 6 cm in greatest dimension and ENE(-). (from AJCC 8th Ed.)


PSA Level Greater than 0.3

description: A blood concentration of prostate specific antigen greater than 0.3 ng/mL.


Flat Tympanometry Result

description: A tympanometry test result indicating the lack of movement of the tympanic membrane due to middle ear pathology.


pN2b TNM Finding

description: A pathologic regional lymph node TNM finding. The definition of pN2b finding depends on the particular type of cancer that it refers to; for example, for breast cancer, pN2b finding is defined as follows: cancer with metastases in clinically detected internal mammary lymph nodes with or without microscopic confirmation; with pathologically negative axillary nodes. (from AJCC 8th Ed.)


name: Other Specified Persistent Mood Disorders

description: Evidence of other specified persistent mood disorders not specified elsewhere.


name: Recurrent Human Papillomavirus-Related Malignant Neoplasm

description: The reemergence of human papillomavirus-related malignant neoplasm after a period of remission.


name: Acute Myeloid Leukemia with TBL1XR1-RARA

description: Acute myeloid leukemia with variant RARA rearrangement and expression of TBL1XR1-RARA fusion protein.


name: Stage IIB Gestational Trophoblastic Tumor AJCC v7

description: Stage IIB includes: T2, M0, Risk factors: high risk.  T2: Tumor extends to other genital structures (ovary, tube, vagina, broad ligaments) by metastasis or direct extension.  M0: No distant metastasis.  (AJCC 7th ed.)


Drug-induced gingival hyperplasia

description: Overgrowth of the gingival tissue caused by phenytoin, cyclosporine A, and calcium channel blockers.


Grade 5 Penile Infection, CTCAE

description: Death


Stage IB Cervical Cancer FIGO 2018

description: Invasive cervical carcinoma with measured deepest invasion equal or more than 5 mm (greater than Stage IA), lesion limited to the cervix uteri. (FIGO 2018)


name: Uterine Corpus Adenosarcoma pT3 TNM Finding v8

description: Uterine corpus adenosarcoma with tumor infiltrating abdominal tissues. (from AJCC 8th Ed.)


Grade 1 Pharyngolaryngeal Pain, CTCAE

description: Mild pain


Albumin Level Finding

description: A finding that indicates the amount of albumin in a sample.


name: Other Symptoms and Signs with Cognitive Functions following Cerebral Infarction

description: Evidence of other symptoms and signs with cognitive functions following cerebral infarction not specified elsewhere.


name: Gastric Cancer pNX TNM Finding v6 and v7

description: Gastric cancer in which the regional lymph nodes cannot be assessed. (from AJCC 6th and 7th Eds.)


10/10 HLA Match

description: Complete HLA matching for HLA-A, -B, -C, -DRB1, and -DQB1 loci.


Hematoma, CTCAE

description: A disorder characterized by a localized collection of blood, usually clotted, in an organ, space, or tissue, due to a break in the wall of a blood vessel.


name: Grade 2 Scrotum Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


Colorectal Cancer pN2 TNM Finding v8

description: Colorectal cancer in which four or more regional lymph nodes are positive. (from AJCC 8th Ed.)


name: Peritoneal Cavity Infection with Unknown Absolute Neutrophil Count, CTCAE


name: Acute Myocardial Injury with Cardiogenic Shock Related to COVID-19

description: Acute myocardial injury with evidence of cardiogenic shock defined as clinical evidence of low cardiac index (e.g., less than 2.2 L/min/m2) accompanied by impaired tissue perfusion in a patient with probable or confirmed acute COVID-19.


name: Radiating Chest Pain Along Sternal Border

description: The location of the radiating chest pain is along the lateral edge of the sternum.


name: Major Salivary Gland Cancer cN3a TNM Finding v8

description: Major salivary gland cancer with metastasis in a lymph node larger than 6 cm in greatest dimension and ENE(-). (from AJCC 8th Ed.)


Recurrent Lymphoma

description: The reemergence of a lymphoma after a period of remission.


name: Enteropathic Arthropathies, Unspecified Site

description: Evidence of enteropathic arthropathies in an unspecified site.


name: Thyrotoxicosis with Toxic Single Thyroid Nodule with Thyrotoxic Crisis

description: Evidence of thyrotoxicosis with toxic single thyroid nodule with thyrotoxic crisis.