RSR' by ECG Finding

description: An electrocardiographic finding in which there are two R waves, which are two deflections above the baseline resulting from a single ventricular depolarization. The first upward deflection in the complex is the R wave. The S is the first downward deflection. A second upward deflection is called the R-prime wave.


name: PME40_ARATH Probable pectinesterase/pectinesterase inhibitor 40 (sprot)

description: A protein that is a translation product of the PME40 gene in Arabidopsis thaliana.


A carboxylic ester resulting from the formal condensation of the carboxy group of isobutyric acid with the 1-hydroxy group of 2,4,4-trimethylpentane-1,3-diol.


name: Thrombolysis in Myocardial Infarction Flow-0

category: biolink:PhenotypicFeature biolink:DiseaseOrPhenotypicFeature biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing

description: No perfusion: No antegrade flow beyond the point of occlusion. (www.TIMI.org accessed 21SEP2011) (ACC)


name: Thrombolysis in Myocardial Infarction Flow

description: A grading system for coronary blood flow based on the classification developed by the Thrombolysis in Myocardial Infarction Group. It classifies coronary blood flow into four classes based upon the angiographic appearance of the blood vessels. (ACC)


name: Thrombolysis in Myocardial Infarction Flow-1

description: Penetration without perfusion: The contrast material passes beyond the area of obstruction, but fails to opacify the entire coronary bed distal to the obstruction for the duration of the cine run.  (www.TIMI.org accessed 21SEP2011) (ACC)


name: Thrombolysis in Myocardial Infarction Flow-3

description: Complete perfusion: Antegrade flow into the bed distal to the obstruction occurs as promptly as into the bed proximal to the obstruction and clearance of contrast material from the involved bed is as rapid as from an uninvolved bed in the same vessel or the opposite artery. (www.TIMI.org accessed 21SEP2011) (ACC)


name: Thrombolysis in Myocardial Infarction Flow-2

description: Partial reperfusion: The contrast material passes across the obstruction and opacifies the entire coronary bed distal to the obstruction. However, the rate of entry of contrast into the vessel distal to the obstruction and/or its rate of clearance from the distal bed are perceptibly slower than its entry into and/or clearance from comparable areas not perfused by the culprit vessel (e.g., the opposite coronary artery or coronary bed proximal to the obstruction).(www.TIMI.org accessed 21SEP2011) (ACC)


A dialkylglycerol that is glycerol alkylated at positions 1 and 2 by phytanyl groups with (R)-configuration at position 2.


name: Y6352_DICDI Putative uncharacterized protein DDB_G0285119 (sprot)

description: A protein that is a translation product of the DDB_G0285119 gene in Dictyostelium discoideum.


name: Metastatic Malignant Neoplasm to the Thyroid

category: biolink:Disease biolink:DiseaseOrPhenotypicFeature biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing

description: A malignant neoplasm either directly extending to the thyroid gland from adjacent structures (e.g. pharynx, larynx, esophagus, cervical lymph nodes), or spreading to the thyroid gland from distant anatomic sites, most frequently kidney, lung, uterus, breast, and skin.  The majority of cases are carcinomas, lymphomas, and melanomas.


Metastatic malignant neoplasm to neck

description: A malignant neoplasm that has spread to the neck region from a malignancy in a local or distant anatomic site.


name: Metastatic malignant neoplasm to parathyroid gland

description: A malignant neoplasm either directly extending to the parathyroid glands from adjacent anatomic structures, or spreading to the parathyroid glands from distant anatomic sites, most frequently breast, lung, kidney, soft tissues, and skin.


name: Metastatic malignant neoplasm to nasopharynx

description: A malignant neoplasm that has spread to the nasopharynx from another anatomic site.


name: Metastatic malignant neoplasm to oropharynx

description: A malignant neoplasm that has spread to the oropharynx from another anatomic site.


name: Metastatic malignant neoplasm to hypopharynx

description: A malignant neoplasm that has spread to the hypopharynx from another anatomic site.


Metastatic malignant neoplasm to larynx

description: A malignant neoplasm that has spread to the larynx from another anatomic site.


name: Neck Squamous Cell Carcinoma of Unknown Primary

description: A squamous cell carcinoma that has metastasized to the neck lymph nodes from an unknown primary anatomic site.


name: Recurrent Neck Squamous Cell Carcinoma of Unknown Primary

description: The reemergence of metastatic squamous cell carcinoma of unknown primary in the neck region after a period of remission.


name: Metastatic malignant neoplasm to pharynx

description: A malignant neoplasm that has spread to the pharynx from another anatomic site.


name: Human Papillomavirus-Related Head and Neck Squamous Cell Carcinoma of Unknown Primary

description: A squamous cell carcinoma that is associated with human papillomavirus infection and has metastasized to the neck lymph nodes from an unknown primary anatomic site.


name: Human Papillomavirus-Negative Head and Neck Squamous Cell Carcinoma of Unknown Primary

description: A squamous cell carcinoma that is not associated with human papillomavirus infection and has metastasized to the neck lymph nodes from an unknown primary anatomic site.


name: BOS complex subunit ncln isoform 2 (zebrafish)

description: A BOS complex subunit ncln (zebrafish) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q6NZ07-2.


name: HEY2_MOUSE Hairy/enhancer-of-split related with YRPW motif protein 2 (sprot)

description: A hairy/enhancer-of-split related with YRPW motif protein 2 that is encoded in the genome of mouse.


Verruca plana

description: Slightly raised wart 2-5 mm in diameter often associated with viral infections, commonly persistent in immunodeficient individuals.


name: protein max isoform long unmodified form

description: A protein max isoform long that has not been subjected to any co- or post-translational residue modification or peptide bond cleavage.


protein max isoform long

A protein max that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P61244-1 or a 1:1 ortholog thereof.


name: protein max isoform long phosphorylated 1 (human)

description: A protein max isoform long phosphorylated 1 in human. UniProtKB:P61244-1, Ser-2/Ser-11, MOD:00046.


protein max isoform long (human)

A protein max isoform long that is encoded in the genome of human.


name: protein max isoform long phosphorylated 1

description: A protein max isoform long that has been phosphorylated at two Ser residues in the N-terminal region. Example: UniProtKB:P61244-1, Ser-2/Ser-11, MOD:00046.


protein max isoform Long (rat)

A protein max isoform long that is encoded in the genome of rat.


protein max isoform 1 (mouse)

A protein max isoform long that is encoded in the genome of mouse.


name: CK097_HUMAN Uncharacterized protein C11orf97 (sprot)

description: An uncharacterized protein C11orf97 that is encoded in the genome of human.


NIS1_YEAST Protein NIS1 (sprot)

A protein that is a translation product of the NIS1 gene in yeast.


name: linker for activation of T-cells family member 1 isoform h3 (human)

description: A linker for activation of T-cells family member 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O43561-3.


name: linker for activation of T-cells family member 1

description: A protein that is a translation product of the human LAT gene or a 1:1 ortholog thereof.


name: linker for activation of T-cells family member 1 isoform h2 (human)

description: A linker for activation of T-cells family member 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O43561-2.


name: LAT_RAT Linker for activation of T-cells family member 1 (sprot)

description: A linker for activation of T-cells family member 1 that is encoded in the genome of rat.


name: linker for activation of T-cells family member 1 isoform h4 (human)

description: A linker for activation of T-cells family member 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O43561-4.


name: linker for activation of T-cells family member 1 phosphorylated 2 (human)

description: A linker for activation of T-cells family member 1 (human) that has been post-translationally modified to include phosphotyrosine at positions 200 and 220 of the amino acid sequence represented by UniProtKB:O43561. UniProtKB:O43561, Tyr-200/Tyr-220, MOD:00048.


name: LAT_HUMAN Linker for activation of T-cells family member 1 (sprot)

description: A linker for activation of T-cells family member 1 that is encoded in the genome of human.


name: linker for activation of T-cells family member 1 isoform h5 (human)

description: A linker for activation of T-cells family member 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O43561-5.


name: LAT_MOUSE Linker for activation of T-cells family member 1 (sprot)

description: A linker for activation of T-cells family member 1 that is encoded in the genome of mouse.


name: linker for activation of T-cells family member 1 phosphorylated 1 (human)

description: A linker for activation of T-cells family member 1 (human) that has been post-translationally modified to include phosphotyrosine at positions 156, 161, 200, 220 and 255 of the amino acid sequence represented by UniProtKB:O43561. UniProtKB:O43561, Tyr-156/Tyr-161/Tyr-200/Tyr-220/Tyr-255, MOD:00048.


name: linker for activation of T-cells family member 1 isoform h1 (human)

description: A linker for activation of T-cells family member 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O43561-1.


name: linker for activation of T-cells family member 1 isoform h2 phosphorylated 1 (human)

description: A linker for activation of T-cells family member 1 isoform h2 (human) that has been phosphorylated on the residues at the positions equivalent to Tyr-127, Tyr-132, Tyr-171, Tyr-191, and Tyr-226 of the amino acid sequence represented by UniProtKB:O43561-2. UniProtKB:O43561-2, Tyr-127/Tyr-132/Tyr-171/Tyr-191/Tyr-226, MOD:00048.


name: BIN2_MOUSE Bridging integrator 2 (sprot)

description: A bridging integrator 2 that is encoded in the genome of mouse.


name: bridging integrator 2 cysteinylated 1 (mouse)

description: A bridging integrator 2 (mouse) that has been cysteinylated on the residue at the position equivalent to Cys-205 of the amino acid sequence represented by UniProtKB:D3Z6Q9. UniProtKB:D3Z6Q9, Cys-205, MOD:00765.


myrothenone A

An alicyclic ketone which is 3-oxocyclopent-1-ene substituted by a formamido group at position 1 as well as vinyl and hydroxy groups at position 4. It is isolated from a marine derived fungus Myrothecium sp. and acts as an inhibitor of tyrosinase enzyme (EC 1.14.18.1).


TP53-target gene 5 protein

A protein that is a translation product of the human TP53TG5 gene or a 1:1 ortholog thereof.


name: TP53-target gene 5 protein phosphorylated 1 (human)

description: A TP53-target gene 5 protein (human) that has been phosphorylated on the residue at the position equivalent to Thr-262 of the amino acid sequence represented by UniProtKB:Q9Y2B4. UniProtKB:Q9Y2B4, Thr-262, MOD:00047.


name: T53G5_HUMAN TP53-target gene 5 protein (sprot)

description: A TP53-target gene 5 protein that is encoded in the genome of human.


Hypoplastic iris stroma

description: Underdevelopment of the stroma of iris.


name: transmembrane protease serine 13 isoform h1 (human)

description: A transmembrane protease serine 13 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9BYE2-1.


name: serum paraoxonase/arylesterase 1 isoform 1 (rat)

description: A serum paraoxonase/arylesterase 1 isoform 1 that is encoded in the genome of rat.


name: serum paraoxonase/arylesterase 1 isoform 1

description: A serum paraoxonase/arylesterase 1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P27169-1 or a 1:1 ortholog thereof.


name: serum paraoxonase/arylesterase 1 isoform 1 (mouse)

description: A serum paraoxonase/arylesterase 1 isoform 1 that is encoded in the genome of mouse.


name: serum paraoxonase/arylesterase 1 isoform 1 (human)

description: A serum paraoxonase/arylesterase 1 isoform 1 that is encoded in the genome of human.


name: diphthamide biosynthesis protein 3 isoform 1 (human)

description: A DPH3 isoform 1 that is encoded in the genome of human.


CLC_DROME Clathrin light chain (sprot)

A clathrin light chain B that is encoded in the genome of fruit fly.


name: Gastrointestinal Stromal Tumor cM1 TNM Finding v7

description: Gastrointestinal stromal tumor with distant metastasis. (from AJCC 7th Ed.)


name: YEHX_ECOLI Glycine betaine uptake system ATP-binding protein YehX (sprot)

description: A glycine betaine uptake system ATP-binding protein YehX that is encoded in the genome of Escherichia coli K-12.


name: actin filament-associated protein 1-like 2 isoform m1 (mouse)

description: An actin filament-associated protein 1-like 2 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q5DTU0-1.


name: AF1L2_MOUSE Actin filament-associated protein 1-like 2 (sprot)

description: An actin filament-associated protein 1-like 2 that is encoded in the genome of mouse.


name: actin filament-associated protein 1-like 2 isoform m2 (mouse)

description: An actin filament-associated protein 1-like 2 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q5DTU0-2.


name: U6 snRNA-associated Sm-like protein LSm8, initiator methionine removed form

description: A U6 snRNA-associated Sm-like protein LSm8 that has had the initiator methionine removed.


name: U6 snRNA-associated Sm-like protein LSm8, initiator methionine removed form (human)

description: A U6 snRNA-associated Sm-like protein LSm8 (human) that has had the initiator methionine removed. UniProtKB:O95777, 2-96.


erlin-1 isoform 1 (mouse)

An erlin-1 isoform 1 that is encoded in the genome of mouse.


jaspamide O

A cyclodepsipeptide isolated from Jaspis splendens. A derivative of jaspamide, it has been shown to exhibit cytotoxic and microfilament disruption activity.


Vaginal Cancer pT2a TNM Finding v8

description: Vaginal cancer with tumor invading paravaginal tissues but not to pelvic wall, measuring 2.0 cm or less. (from AJCC 8th Ed.)


A hydroperoxyicosatrienoic acid that is (8Z,11Z,14Z)-icosatrienoic acid in which the hydroperoxy substituent is located at position 10.


19-hydroxyprostaglandin H2

A prostaglandin H that consists of prostaglandin H2 bearing an additional hydroxy substituent at position 19.


A HETE that is (5Z,8Z,12E,14Z)-icosa-5,8,12,14-tetraenoic acid substituted at position 11 by a hydroxy group.


leukotriene E3

A leukotriene that is leukotriene E4 in which the non-conjugated double bond has been reduced to a single bond.


A hydroperoxy(hydroxy)icosatetraenoic acid that is (7E,9E,11Z,13E)-icosatetraenoic acid carrying 2 hydroxy substituents at positions 5S and 6R as well as a hydroperoxy substituent at position 15S.


18-hydroxythromboxane A2

A thromboxane A that is thromboxane A2 carrying an additional hydroxy substituent at position 18.


trans-2-icosenoic acid

An icosenoic acid in which the double bond is at the 2-3 position and has E configuration.


prostaglandin D2 1-glyceryl ester

A 1-monoglyceride resulting from the condensation of the carboxy group of prostaglandin D2 with the 1-hydroxy group of glycerol.


An 11-HETE in which the chiral centre at position 11 has R-configuration.


Ab 8,15-DiHETE that is derived from (5Z,9E,11Z,13E)-icosatetraenoic acid and has (8S,15S)-stereochemistry.


A hydroperoxy fatty acid that is (14R,15S)-epoxy-(6E,8Z,11Z)-icosatrienoic acid in which the hydroperoxy group is located at position 5S.


An EpETE obtained by formal epoxidation of the 17,18-double bond of all-cis-5,8,11,14,17-icosapentaenoic acid.


A bis(hydroperoxy)icosatetraenoic acid that is (6E,8Z,11Z,13E)-icosatetraenoic acid in which the two hydroperoxy groups are located at positions 5S and 15S.


6-trans-leukotriene B4

A leukotriene that is the 6-trans-isomer of leukotriene B4.


An epoxy(hydroxy)icosatrienoic acid that is the (8S,9S)-epoxy-(10R)-hydroxy derivative of icosa-(5Z,11Z,14Z)-trienoic acid.


An icosanoid that is (5Z,9E,11Z,13E)-icosatetraenoic acid carrying two hydroperoxy substituents at positions 8 and 15 (the 8S,15S-stereoisomer).


name: 17-phenoxy trinor Prostaglandin F2alpha isopropyl ester


A DHET obtained by formal dihydroxylation across the 8,9-double bond of arachidonic acid.


prostaglandin E2 2-glyceryl ester

A 2-monoglyceride obtained by formal condensation of the carboxy group of prostaglandin E2 with the 2-hydroxy group of glycerol.


A (5Z,8Z,11Z)-14,15-dihydroxyicosatrienoic acid in which the two stereocentres at positions 14 and 15 both have R-configuration.


A HETE having a (12R)-hydroxy group and (5Z)-, (8Z)-, (10E)- and (14Z)-double bonds.


tafluprost

A prostaglandin Falpha that is prostaglandin F2alpha in which the carboxylic acid function has been converted to the corresponding isopropyl ester and the 3-hydroxy-1-octenyl side-chain is substituted by 3,3-difluoro-4-phenoxybut-1-enyl. Used for treatment of elevated intraocular pressure in patients with open-angle glaucoma or ocular hypertension.


An HETE having a 9-hydroxy group and (5E)-, (7Z)-, (11Z)- and (14Z)-double bonds.


20,20-dihydroxyleukotriene B4

A leukotriene that is leukotriene B4 in which two of the methyl hydrogens at position 20 have been replaced by hydroxy groups.


leukotriene E4 methyl ester

The methyl ester of leukotriene E4, the esterified acid group being the one forming position 1 of the icosatetraenyl chain. Leukotriene E4 methyl ester is a more lipid-soluble form of leukotriene E4.


A leukotriene that is the 11-trans-isomer of leukotriene E4.


prostaglandin G2 2-glyceryl ester

A 2-monoglyceride obtained by formal condensation of the carboxy group of prostaglandin G2 with the 2-hydroxy group of glycerol.


name: Prostaglandin E2 p-benzamidophenyl ester


An icosanoid that is (6E,8Z,10E,14Z)-icosatetraenoic acid substituted at positions 5 and 12 by oxo and hydroxy groups respectively.


An optically active form of 15-HETE having 15(S)-configuration..


name: 17-trifluoromethylphenyl-13,14-dihydro trinor Prostaglandin F1alpha


15-deoxy-Δ-12,14-prostaglandin J2

A prostaglandin J derivative comprising prostaglandin J2 lacking the 15-hydroxy group and having C=C double bonds at the 12- and 14-positions.


leukotriene B5

A leukotriene composed of (6Z,8E,10E,14Z,17Z)-icosapentaenoic acid carrying (5S)- and (12R)-hydroxy substituents.


2,3,4,5-tetranor-thromboxane B1

A monocarboxylic acid that is thromboxane B1 which is lacking four methylenes in the carboxyalkyl chain. It is a urinary metabolite of thromboxane B2.


An epoxy(hydroxy)icosatrienoic acid that is (8Z,11Z,14Z)-icosatrienoic acid having the epoxide group across positions 5-6 and the hydroxy substituent located at position 20.


A trihydroxyicosatrienoic acid that is (5Z,8Z,13E)-icosatrienoic acid in which the three hydroxy groups are located at positions 11, 12 and 15.


eoxin E4

A leukotriene that is the 14R-(S-cysteinyl),15S-hydroxy derivative of (5Z,8Z,10E,12E)-icosa-7,9,11,14-tetraenoic acid.


unoprostone isopropyl

The isopropyl ester of unoprostone.


20-oxoleukotriene B4

A leukotriene that is leukotriene B4 bearing an additional oxo substituent at position 20.


A prostanoid that is 18,19,20-trinor-prostaglandin D2 in which one of the terminal methyl hydrogens has been replaced by a phenyl group.


12-oxo-20-hydroxyleukotriene B4

A member of the class of leukotrienes that is leukotriene B4 in which the hydroxy group at position 12 has been oxidised to the corresponding ketone and one of the methyl hydrogens at position 20 replaced by a hydroxy group.


prostaglandin J3

A member of the class of prostaglandins J that is (5Z,9Z,13E,17Z)-prostatetraenoic acid carrying hydroxy and oxo substituents at positions 11 and 15 respectively. An intermediate of specialised proresolving mediators


An 11,12-EET in which the epoxy moiety has 11R,12S-configuration.


6-epi-lipoxin A4

A C20 hydroxy fatty acid having (5S)-, (6S)- and (15S)-hydroxy groups as well as (7E)- (9E)-, (11Z)- and (13E)-double bonds.


A prostaglandin Falpha obtained by formal oxidation of the 15-hydroxy group and hydrogenation of the 13,14-double bond of prostaglandin F2alpha.


2,3,4,5-tetranor-prostaglandin FM

A prostanoid that is prostaglandin E2-UM in which the oxo group at position 9 has been reduced to the corresponding alcohol (alpha-configuration).


A prostanoid-LPC that is the ammonium betaine of a 2-(prostaglandin H2)-sn-glycero-3-phosphocholine arising from deprotonation of the phosphate OH group; major species at pH 7.3.


prostaglandin F2beta

A prostaglandins Falpha that is prosta-5,13-dien-1-oic acid substituted by hydroxy groups at positions 9, 11 and 15. It is the 9beta-hydroxy epimer of prostaglandin F2alpha.


A trienoic fatty acid consisting of (8Z,11Z,14Z)-icosa-8,11,14-trienoic acid having additional (7R)-hydroxy- and (5S,6S)-epoxy groups.


aspirin triggered lipoxin A4

A C20 hydroxy polyunsaturated fatty acid having (5S)-, (6R)- and (15R)-hydroxy groups as well as (7E)- (9E)-, (11Z)- and (13E)-double bonds.


An epoxy(hydroxy)icosatrienoic acid that is (5Z,8Z,14Z)-icosatrienoic acid having the epoxide group across positions 11-12 and the hydroxy substituent located at position 20.


A member of the class of prostaglandins Falpha that is 15-oxo-prostaglandin F2alpha in which the methyl group has been oxidised to the corresponding carboxylic acid and in which the double bond at positions 13-14 has been reduced to a single bond.


nonclassic icosanoid

Any biologically active signalling molecule made by oxygenation of C20 fatty acids other than the classic icosanoids (the leukotrienes and the prostanoids).


leukotriene C4 methyl ester

The methyl ester of leukotriene C4, the esterified acid group being the one forming position 1 of the icosatetraenyl chain.  Leukotriene C4 methyl ester is a more lipid-soluble form of leukotriene C4.


eoxin D4

A leukotriene that is the 14R-(S-cysteinylglycyl),15S-hydroxy derivative of (5Z,8Z,10E,12E)-icosa-7,9,11,14-tetraenoic acid.


gadelaidic acid

An icosenoic acid having a trans- double bond at position 9.


A hydroperoxy fatty acid that is (8Z,10E,14Z)-icosatrienoic acid in which the hydroperoxy group is located at the 12(S)-position.


An epoxy(hydroxy)icosatrienoic acid consisting of (5Z,9E,14Z)-icosa-5,9,14-trienoic acid having additional (8R)-hydroxy- and (11S,12S)-epoxy groups.


DHET

An icosanoid obtained by formal dihydroxylation across one of the double bonds of arachidonic acid.


An optically active form of 15-HETE having 15(R)-configuration.


A leukotriene that is 10,11-dihydroleukotriene B4 in which two of the methyl hydrogens at position 20 have been replaced by hydroxy groups.


A 9-HPETE in which the 9-hydroxy group has S stereochemistry.


19-hydroxyprostaglandin I2

A prostaglandin I that consists of prostaglandin I1 carrying an additional hydroxy substituent at position 19.


(Z)-icos-13-enoic acid

An icosenoic acid having a cis- double bond at position 13.


eoxin

Oxylipins that derive from eicosanoids.


An epoxy(hydroxy)icosatrienoic acid that is (5Z,8Z,12E)-icosatrienoic acid having the epoxide group across positions 14-15 and the hydroxy substituent located at position 11.


13,14-dihydro-15-oxolipoxin A4

A C20 hydroxy fatty acid obtained by formal hydrogenation across the 13,-14-double bond of 15-oxolipoxin A4.


prostaglandin B3

A member of the class of prostaglandins A that is prosta-5,8(12),13,17-tetraen-1-oic acid carrying oxo and hydsroxy substituents at positions 9 and 15 respectively (the 5Z,13E,15S,17Z-stereoisomer).


name: 16-phenyl tetranor Prostaglandin F2alpha


A HETE having a (12S)-hydroxy group and (5Z)-, (8Z)-, (10E)- and (14Z)-double bonds.


12-epi LTB4

A leukotriene that is the 12S-isomer of leukotriene B4.


A member of the class of prostaglandins J that is prosta-5,9,12-trien-1-oic acid carrying oxo and hydsroxy substituents at positions 11 and 15 respectively (the 5Z,12E,15S-stereoisomer).


11-dehydro-thromboxane B2

A thromboxane obtained by formal oxidation of the hemiacetal hydroxy function of thromboxane B2.


A hydroperoxy(hydroxy)icosatetraenoic acid that is (6E,8Z,11Z,13E)-icosatetraenoic acid in which the hydroxy and hydroperoxy substituents are located at positions 5S and 15S respectively.


prostaglandin F2alpha 2-glyceryl ester

A 2-monoglyceride obtained by formal condensation of the carboxy group of prostaglandin F2alpha with the 2-hydroxy group of glycerol.


A HPETE in which the hydroxy group is located at position 9 with the four double bonds at positions 5, 7, 11 and 14 (the 5Z,7E,11Z,14Z geoisomer).


prostaglandin D3

A member of the class of prostaglandins D that is prosta-5,13,17-trien-1-oic acid substituted by hydroxy groups at positions 9 and 15 and an oxo group at position 11 (the 5Z,13E,15S,17Z-stereoisomer).


A polyunsaturated fatty acid that is (6E,8Z,11Z,14Z,16E)-icosapentaenoic acid substituted at positions 5 and 18 by hydroperoxy and hydroxy groups respectively (the 5S, 18S-stereoisomer).


name: (1S,2R)-3-oxo-2-pentylcyclopentane-1-octanoic acid methyl ester


An icosanoid that is any icosatetraenoic acid bearing hydroxy and hydroperoxy substituents. An oxidation product of icosatetraenoic acid metabolism.


name: 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl]-5-heptenoic acid propan-2-yl ester


5,8,11-icosatriynoic acid

A C20 polyunsaturated fatty acid having three triple bonds in the 5-, 8- and 11-positions.


A bis(hydroperoxy)icosatetraenoic acid that is (5Z,8Z,10E,12E)-icosatetraenoic acid carrying two hydroperoxy substituents at positions 14 and 15 (the 14R,15S-stereoisomer).


A HETE that is arachidonic acid carrying a hydroxy substituent at position 7.


18-carboxy-19,20-dinor-leukotriene E4

An icosanoid that is leukotriene E4 in which two methylene groups are removed from the carboxyalkyl chain attached to the non-conjugated double bond.


An 8,9-EET in which the epoxy moiety has 8S,9R-configuration.


An epoxy(hydroxy)icosatrienoic acid consisting of (5Z,9E,14Z)-icosa-5,9,14-trienoic acid having additional (8R)-hydroxy- and (11R,12R)-epoxy groups.


10,11-dihydro-12-oxoleukotriene B4

A hydroxy polyunsaturated fatty acid that is (6Z,8E,14Z)-icosatrienoic acid carrying hydroxy and oxo substituents at positions 5 and 12 respectively.


A 16-carboxy-Delta(13)-17,18,19,20-tetranor-leukotriene E4 in which the double bond at position 13-14 has E-configuration.


A prostanoid that is 2,3-dinor-6-oxo-prostaglandin F1alpha in which a hydrogen at position 19 is replaced by a hydroxy group.


A HETE that is arachidonic acid carrying a hydroxy substituent at position 10.


name: 5-trans-17-phenyl trinor Prostaglandin F2alpha ethyl amide


A DiHETE that is (6E,8Z,12E,14Z)-icosatetraenoic acid in which the two hydroxy substituents are placed at the 5S- and 11R-positions.


eoxin A4

An oxylipin that is the (14S,15S)-epoxy derivative of (5Z,8Z,10E,12E)-icosa-5,8,10,12-tetraenoic acid.


A (5Z,8Z,11Z)-14,15-dihydroxyicosatrienoic acid in which the two stereocentres at positions 14 and 15 both have S-configuration.


A polyunsaturated fatty acid consisting of (7E,9E,11Z,14Z,16E)-icosapentaenoic acid carrying additional 18-hydroxy and (5S,6S)-epoxy groups.


A 2-acyl-sn-glycero-3-phosphoethanolamine in which the acyl group is specified as (9S,11R)-epidioxy-(15S)-hydroperoxy-(5Z,13E)-prostadienoyl.


leukotriene F4

A leukotriene composed of (7E,9E,11Z,14Z)-icosa-7,9,11,14-tetraenoic acid having (5S)-hydroxy and (6R)-(L-gamma-glutamyl-L-cystein-S-yl) substituents.


19-hydroxyleukotriene B4

A leukotriene that is leukotriene B4 carrying an additional hydroxy substituent at position 19.


A DiHETE that is (5Z,8Z,10E,12E)-icosatetraenoic acid carrying two hydroxy substituents at positions 14 and 15 (the 14R,15S-stereoisomer).


epoxy(hydroxy)icosatrienoic acid

A nonclassic icosanoid that consists of any icosatrienoic acid carrying epoxy and hydroxy substituents.


A HETE having an (8S)-hydroxy group and (5Z)-, (9E)-, (11Z)- and (14Z)-double bonds.


A 16-HETE in which the chiral centre at position 16 has S-configuration.


A hydroperoxy fatty acid that is (5Z,8Z,10E)-icosatrienoic acid in which the hydroperoxy group is located at the 12(S)-position.


An 11-HETE in which the chiral centre at position 11 has S-configuration.


A HETE that is arachidonic acid carrying a hydroxy substituent at position 13.


prostaglandin H2 2-glyceryl ester

A 2-monoglyceride obtained by formal condensation of the carboxy group of prostaglandin H2 with the 2-hydroxy group of glycerol.


An icosatetraenoic acid in which the double bonds are located at the 6-7, 8-9, 11-12, and 14-15 positions and have E, Z, Z, and Z geometry, respectively, and in which the pro-S hydrogen is substituted by a hydroperoxy group.


Delta(6)-trans-12-epi-leukotriene B4

A leukotriene that is the 6-trans,12S-isomer of leukotriene B4.


A  clavulone that is a chlorinated prostanoid isolated from marine corals.


lipoxin

A nonclassic icosanoid and signalling molecule that has four conjugated double bonds and is derived from arachidonic acid.


A HPETE that consists of (6E,8Z,11Z,14Z)-icosatetraenoic acid in which the hydroperoxy group is located at position 5.


6-oxoprostaglandin E1

A prostaglandin E that is prostaglandin E1 bearing a keto substituent at the 6-position.


A HETE having a (9S)-hydroxy group and (5Z)-, (7E)-, (11Z)- and (14Z)-double bonds.


A DiHETE that is 5-HETE carrying an additional hydroxy substituent at position 20.


12-oxo-6-trans-leukotriene B4

A leukotriene consisting of 6-trans-leukotriene B4 having a 12-keto group in place of the 12-hydroxy group.


A 17(18)-EpETE in which the epoxy group has (17R,18S)-configuration.


A 2-acyl-sn-glycero-3-phosphoethanolamine in which the acyl group is specified as (5Z,13E,15S)-11alpha,15-dihydroxy-9-oxoprosta-5,13-dien-1-oyl


A prostaglandin Falpha obtained by formal oxidation of the 15-hydroxy group and hydrogenation of the 13,14-double bond of prostaglandin F1alpha.


bis(hydroperoxy)icosatetraenoic acid

An icosanoid that consists of any icosatetraenoic acid carrying two hydroperoxy substituents at unspecified positions.


prostaglandin H3

A member of the class of prostaglandins H that is 9,11-epidioxyprosta-5,13,17-trienoic acid carrying an additional hydroxy substituent at the 15S-position.


A hydroperoxy fatty acid that is (8Z,10E,14Z)-icosatrienoic acid in which the hydroperoxy group is located at position 12.


15-deoxy-Delta(12,14)-prostaglandin D2

A prostaglandin D derivative that is prostaglandin D2 lacking the 15-hydroxy group and having C=C double bonds at positions 12(13) and 14(15).


A leukotriene compound having double bonds in the 7-, 9-, 11- and 14-positions and 5(S)- and 6(S)-hydroxy substituents.


10,11-dihydroleukotriene B4

A leukotriene obtained by formal dehydrogenation of the 10,11-double bond in leukotriene B4.


An epoxy(hydroxy)icosatrienoic acid consisting of (5Z,8Z,11Z)-icosa-5,9,14-trienoic acid having additional (13R)-hydroxy- and (14S,15S)-epoxy groups.


A HETE that is icosa-5,8,10,14-tetraenoic acid substituted by a hydroxy group at position 12. It is a metabolite of arachidonic acid.


An HETE having a 8-hydroxy group and (5Z)-, (9E)-, (11Z)- and (14Z)-double bonds.


An epoxy(hydroxy)icosatrienoic acid that is (5Z,11Z,14Z)-icosatrienoic acid having the epoxide group across positions 8-9 and the hydroxy substituent located at position 20.


A trihydroxyicosatrienoic acid that is (5Z,8Z,11Z)-icosatrienoic acid in which the three hydroxy groups are located at positions 13, 14 and 15.


A leukotriene that is the (5S,6S)-epoxy derivative of (7E,9E,11Z,14Z)-icosa-7,9,11,14-tetraenoic acid.


An EpETE obtained by formal epoxidation of the 8,9-double bond of all-cis-5,8,11,14,17-icosapentaenoic acid.


20-hydroxylipoxin B4

A member of the class of lipoxins that is lipoxin B4 carrying an additional hydroxy substituent at position 20.


(R)-PGJ2-S-glutathione conjugate

A glutathione conjugate obtained by formal 1,4-addition of the thiol function of glutathione to the enone function of prostaglandin J2 (where the newly formed stereocentre at position 9 has R-configuration).


prostaglandin H1

A member of the class of prostaglandins H that is prostaglandin H2 lacking the double bond at position 5.


13,14-dihydroprostaglandin F2alpha

A prostaglandins Falpha that is prost-5-en-1-oic acid substituted by hydroxy groups at positions 9, 11 and 15.


15-oxolipoxin A4

A C20 hydroxy fatty acid having (5S)- and (6R)- -hydroxy groups as well as a 15-oxo group and (7E)- (9E)-, (11Z)- and (13E)-double bonds.


A polyunsaturated fatty acid that is (6E,8Z,11Z,14Z,16E)-icosapentaenoic acid substituted at positions 5 and 18 by hydroperoxy and hydroxy groups respectively (the 5S, 18R-stereoisomer).


A HETE having a (19S)-hydroxy group and all-cis double bonds at positions 5, 8, 11 and 14.


A HETE that consists of arachidonic acid bearing an additional hydroxy substituent at position 17.


trihydroxyicosatrienoic acid

A nonclassic icosanoid that consists of any icosatrienoic acid carrying three hydroxy substituents.


A HPETE that is (5Z,8Z,10E,12R,14Z)-icosa-5,8,10,14-tetraenoic acid with the hydroperoxy group located at position 12 (the R-enantiomer).


A trihydroxyicosatrienoic acid that is (5Z,8Z,12E)-icosatrienoic acid in which the three hydroxy groups are located at positions 11, 14 and 15.


A leukotriene that is (5S,7E,9E,12R,14Z)-5,12-dihydroxyicosa-7,9,14-trienoic acid to which a glutathionyl group is attached at position 6 via a sulfide linkage.


N-acetylleukotriene E4

A leukotriene that is (7E,9E,11Z,14Z)-icosa-7,9,11,14-tetraenoic acid substituted by a hydroxy group at position 5 (5S) and an N-acetyl-L-cystein-S-yl group at position 6 (6R); it is a major bilary metabolite of cysteinyl leukotrienes.


prostaglandin F1alpha alcohol

A member of the class of prostaglandins Falpha that is prostaglandin F1alpha in which the carboxy group has been reduced to the corresponding primary alcohol.


A 5(),6(S)-epoxy-18-hydroxy-(7E,9E,11Z,14Z,16E)-icosapentaenoic acid in which the 18-hydroxy group has S-configuration.


carbocyclic thromboxane A2

A member of the class of thromboxanes that is thromboxane A2 in which the bridging oxygen has been replaced by a methylene group.


name: 13,14-dihydro-15-keto PGF2alpha isopropyl ester


prostaglandin I2 2-glyceryl ester

A 2-monoglyceride obtained by formal condensation of the carboxy group of prostaglandin I2 with the 2-hydroxy group of glycerol.


4,5-leukotriene A4

A leukotriene whose structure comprises leukotriene A4 having a (4R,5R)-epoxy group.


A hydroperoxyicosatrienoic acid that is (8Z,12E,14Z)-icosatrienoic acid in which the hydroperoxy substituent is located at position 11.


thromboxane

A class of oxygenated oxane derivatives, originally derived from prostaglandin precursors in platelets, that stimulate aggregation of platelets and constriction of blood vessels.


leukotriene D3

A leukotriene that is (5S,7E,9E,11Z)-5-hydroxyicosa-7,9,11-trienoic acid in which an L-cysteinylglycinyl group is attached at position 6R via a sulfide linkage.


The (R)-enantiomer of 8-HPETE.


(R)-PGA2-S-glutathione conjugate

A glutathione conjugate obtained by formal 1,4-addition of the thiol function of glutathione to the enone function of prostaglandin A2 (where the newly formed stereocentre at position 11 has R-configuration).


name: 17-phenyl trinor Prostaglandin F2alpha-d4


thromboxane B3

A member of the class of thromboxanes B that is (5Z,13E,17Z)-thromboxa-5,13,17-trien-1-oic acid substituted by hydroxy groups at positions 9, 11 and 15.


(11Z)-icos-11-enoic acid

An icosenoic acid having a cis- double bond at position 11.


A hydroperoxy fatty acid that is (5Z,8Z,10E,14Z,17Z)-icosapentaenoic acid in which the hydroperoxy group is located at the 12-position.


A hydroperoxyicosatrienoic acid that is (9E,11Z,14Z)-icosatrienoic acid in which the hydroperoxy substituent is located at position 8R.


A DiHETE that consists of 6E,8Z,11Z,13E-icosatetraenoic acid having the two hydroxy groups located at positions 5 and 15.


A 13-hydroxy-14,15-epoxy-(5Z,8Z,11Z)-icosatrienoic acid in which the three chiral centres at positions 13, 14 and 15 all have S-configuration.


eoxin C4

A leukotriene that is the 14R-(S-glutathionyl),15S-hydroxy derivative of (5Z,8Z,10E,12E)-icosa-7,9,11,14-tetraenoic acid.


20-hydroxyprostaglandin A1

A prostaglandin A derivative that is prostaglandin A1 in which one of the methyl hydrogens at position 20 has been replaced by a hydroxy group.


hydroperoxyicosapentaenoic acid

A hydroperoxy polyunsaturated fatty acid that is any icosapentaenoic fatty acid carrying a single hydroperoxy substituent.


EpETE

An epoxy fatty acid obtained by formal epoxidation of one of the double bonds of any icosapentaenoic acid.


2,3-dinor-prostaglandin E2

A prostanoid that is prostaglandin E2 lacking two methylenes in the carboxyalkyl chain.


A HETE that consists of arachidonic acid bearing a hydroxy substituent at position 18.


hydroperoxyicosatrienoic acid

A hydroperoxy polyunsaturated fatty acid that is any icosatrienoic fatty acid carrying a single hydroperoxy substituent.


(S)-PGA2-S-glutathione conjugate

A glutathione conjugate obtained by formal 1,4-addition of the thiol function of glutathione to the enone function of prostaglandin A2 (where the newly formed stereocentre at position 11 has S-configuration).


An 8,9-EET in which the epoxy moiety has 8R,9S-configuration.


A dihydroxyicosatetraenoic acid (7E,9E,11Z,14Z)-icosatetraenoic acid in which the two hydroxy substituents are located at positions 5S and 6R.


A C20 hydroxy fatty acid having (5S)-, (14R)- and (15S)-hydroxy groups as well as (6E)- (8Z)-, (10E)- and (12E)-double bonds.


A hydroperoxyicosapentaenoic acid that is (5Z,8Z,11Z,14Z,16E)-icosapentaenoic acid in which the pro-R hydrogen at position 18 has been replaced by a hydroperoxy group. One of the two stereoisomers formed when acetylated COX2 oxidises the omega-3 fatty acid EPA.


A DiHETE that is 8-HETE carrying an additional hydroxy substituent at position 20.


levuglandin

Seco-prostaglandins related formally to the corresponding prostaglandins by aldol condensation.


15-deoxy-Delta(12,14)-prostaglandin A2

A prostaglandin A derivative that is prostaglandin A2 lacking the 15-hydroxy group and having C=C double bonds at positions 12(13) and 14(15).


name: (1S,2R)-3-oxo-2-pentylcyclopentane-1-hexanoic acid methyl ester


Delta(12)-prostaglandin J3

A member of the class of prostaglandins J that is (5Z,9Z,12E,17Z)-prostatetraenoic acid carrying hydroxy and oxo substituents at positions 11 and 15 respectively. An intermediate of specialised proresolving mediators and potent anti-leukemic agent.


A member of the class of lipoxins that is (7E,9E,11Z,13E,17Z)-icosapentaenoic acid carrying three hydroxy substituents at positions 5, 6, and 15R.


A 13-HETE in which the stereocentre at position 13 has S-configuration.


prostaglandin D2 2-glyceryl ester

A 2-monoglyceride resulting from the condensation of the carboxy group of prostaglandin D2 with the 2-hydroxy group of glycerol.


An icosanoid that is (6E,8Z,11Z,14Z,17Z)-icosapentaenoic acid substituted at positions 5 and 20 by hydroxy groups.


20-hydroxyprostaglandin E2

A prostaglandin E derivative that is prostaglandin E2 in which one of the methyl hydrogens at position 20 has been replaced by a hydroxy group.


19-hydroxyprostaglandin H1

A prostaglandin H that consists of prostaglandin H1 bearing an additional hydroxy substituent at position 19.


A DiHETE that is 12-HETE carrying an additional hydroxy substituent at position 20.


prostaglandin F2alpha 1-ethanolamide

An N-acylethanolamine compound formed by a condensation of prostaglandin F2alpha and ethanolamine.


17-icosenoic acid

An icosenoic acid having a double bond at position 17.


A DiHETE that is (6E,8Z,11Z,13E)-icosatetraenoic acid in which the two hydroxy substituents are placed at the 5S- and 15R-positions.


A 16-HETE in which the chiral centre at position 16 has R-configuration.


name: (1S,2S)-3-oxo-2-(2Z-pentenyl)cyclopentane-1-hexanoic acid methyl ester


A 14,15-EET in which the epoxy moiety has 14R,15S-configuration.


name: 15(S)-15-methyl Prostaglandin F2alpha ethyl amide


An 11,12-EET in which the epoxy moiety has 11S,12R-configuration.


11-epi-prostaglandin F2alpha

The prostaglandin F that is the 11-epimer of prostaglandin F2alpha.


A 2-acyl-sn-glycero-3-phosphocholine in which the acyl group is specified as (9S,11R)-epidioxy-(15S)-hydroperoxy-(5Z,13E)-prostadienoyl.


A HPETE that is (5Z,8Z,11Z,13E,15R)-icosa-5,8,11,13-tetraenoic acid with the hydroperoxy group located at position 15 (the R-enantiomer).


EET

An icosanoid obtained by formal epoxidation of one of the double bonds of arachidonic acid.


An icosanoid that is (6E,8Z,11Z,14Z,16E)-icosa-6,8,11,14,16-pentaenoic acid substituted at positions 5S and 18 by hydroperoxy and hydroxy groups respectively.


20-hydroxy-20-oxoleukotriene B4

A member of the class of leukotrienes that is leukotriene B4 in which the terminal methyl group has undergone formal oxidation to the corresponding carboxylic acid.


20-hydroxyprostaglandin E1

A prostaglandin E derivative that is prostaglandin E1 in which one of the methyl hydrogens at position 20 has been replaced by a hydroxy group.


HETE

Any monohydroxylated icosanoid having four double bonds.


A 17(18)-EpETE in which the epoxy group has (17S,18R)-configuration.


A HETE that consists of arachidonic acid bearing a hydroxy substituent at position 19.


20-oxoleukotriene E4

A leukotriene that is leukotriene E4 in which the terminal methyl grop has been oxidised to the corresponding aldehyde


icosenoic acid

An icosanoid comprising icosanoic acid having one C=C bond at any position.


An icosanoid that is leukotriene E3 in which the terminal octyl group is replaced by a carboxymethyl group.


name: 16,16-dimethyl Prostaglandin E2 p-(p-acetamidobenzamido) phenyl ester


The (S)-enantiomer of 15-HPETE.


An icosanoid that is (6E,8Z,11Z,13E)-icosa-6,8,11,13-tetraenoic acid substituted at positions 5 and 15 by hydroperoxy and hydroxy groups respectively.


prostaglandin E2 1-glyceryl ester

A 1-monoglyceride resulting from the condensation of the carboxy group of prostaglandin E2 with the 1-hydroxy group of glycerol.


A 2-acyl-sn-glycero-3-phosphoethanolamine in which the acyl group is specified as (9S,11R)-epidioxy-(15S)-hydroxy-(5Z,13E)-prostadienoyl.


15-dehydroprostaglandin A1

A member of the class of prostaglandins A obtained by oxidation of the 15-hydroxy group of prostaglandin A1 to the corresponding ketone.


A HPETE in which the hydroperoxy group is located at position 8S and the four double bonds at position 5, 9, 11 and 14 (the 5Z,9E,11Z,14Z-geoisomer).


The (5Z,8Z,10E,14Z)-stereoisomer of 12-HETE.


prostanoid

The family of natural prostaglandins and prostaglandin-like compounds including prostacyclins and thromboxanes.


A prostaglandin Falpha that is prostaglandin F1alpha bearing keto substituents at positions 6 and 15.


An O-acyl carbohydrate obtained by the formal condensation of the 20-carboxy group of 20-hydroxy-20-oxoleukotriene B4 with the anomeric hydroxy group of beta-D-glucuronic acid.


An icosanoid that is leukotriene E4 in which the isolated double bond has migrated into conjugation with the triene moiety and in which four methylene groups have been lost from the resulting carboxyalkyl chain.


A 12-HPEPE in which the hydroperoxy group at positions 12 has S-configuration.


13,14-dihydrolipoxin A4

A trienoic fatty acid obtained by formal hydrogenation across the 13,14-double bond of lipoxin A4.


thromboxane B1

A thromboxane B that is thromboxane B2 in which the double bond at position 5-6 has been reduced to a single bond.


20-carboxyleukotriene E4

A leukotriene that is leukotriene E4 in which the terminal methyl grop has been oxidised to the corresponding carboxylic acid.


A HETE that consists of arachidonic acid bearing an additional hydroxy substituent at position 16.


An epoxy(hydroxy)icosatrienoic acid that is (5Z,8Z,11Z)-icosatrienoic acid having the epoxide group across positions 14-15 and the hydroxy substituent located at position 20.


An EET obtained by formal epoxidation of the 11,12-double bond of arachidonic acid.


dihydroxyicosatetraenoic acid

A hydroxy fatty acid that is any eicosatetraenoic acid bearing two hydroxy substituents.


fluprostenol

An organofluorine compound that is racemic prostaglandin F2alpha in which the pentyl group is replaced by a 3-(trifluoromethyl)phenoxymethyl group. A synthetic analogue of prostaglandin F2alpha, ophthalmic solutions of its isopropyl ester prodrug, travoprost, are used as a topical medication for controlling the progression of open-angle glaucoma and ocular hypertension, by reducing intraocular pressure. The isopropyl ester group of travoprost is hydrolysed to the biologically active free acid by esterases in the cornea.


prostaglandin G1

A member of the class of prostaglandins G that is 9alpha,11alpha-epidioxy-13-trans-prostenoic acid carrying an additional hydroperoxy substituent at the 15S-position.


A DiHETE that is (6E,8Z,11Z,13E)-icosatetraenoic acid in which the two hydroxy substituents are placed at the 5S- and 15S-positions.


2,3-dinor-8-epi-prostaglandin F1alpha

A prostanoid that is prostaglandin F1alpha lacking two methylenes in the carboxyalkyl chain and having inverted stereochemistry at the 8-position.


An icosanoid that is (6E,8Z,11Z,13E)-icosatetraenoic acid substituted at positions 5 and 15 by oxo and hydroxy groups respectively.


A 2-acyl-sn-glycero-3-phosphocholine in which the acyl group is specified as (5Z,13E,15S)-11alpha,15-dihydroxy-9-oxoprosta-5,13-dien-1-oyl


name: 16-phenoxy tetranor PGF2alpha cyclopropyl methyl amide


A polyunsaturated fatty acid consisting of (7E,9E,11Z,14Z,16E)-icosapentaenoic acid carrying additional (18R)-hydroxy and (5S,6S)-epoxy groups.


A (5Z,8Z,14Z)-11,12-dihydroxyicosatrienoic acid in which the two stereocentres at positions 11 and 12 both have R-configuration.


name: 8-iso-17-phenyl trinor Prostaglandin F2alpha


A HETE having a 5-hydroxy group and (6E)-, (8Z)-, (11Z)- and (14Z)-double bonds.


clavulone

A class of esterified prostanoids obtained from marine corals.


5,6-epoxyeicosatrienoic acid

An EET obtained by formal epoxidation of the 5,6-double bond of arachidonic acid.


prostaglandin A3

A member of the class of prostaglandins A that is prosta-5,10,13,17-tetraen-1-oic acid carrying oxo and hydroxy substituents at positions 9 and 15 respectively (the 5Z,13E,15S,17Z-stereoisomer).


A (5Z,11Z,14Z)-8,9-dihydroxyicosatrienoic acid in which the two stereocentres at positions 8 and 9 both have R-configuration.


A (5Z,11Z,14Z)-8,9-dihydroxyicosatrienoic acid in which the two stereocentres at positions 8 and 9 both have S-configuration.


A 9-HPETE in which the 9-hydroxy group has R stereochemistry.


prostaglandin C2

A member of the class of prostaglandins C that is prosta-5,11,13-trien-1-oic acid carrying oxo and hydroxy substituents at positions 9 and 15 respectively (the 5Z,13E,15S-stereoisomer).


bimatoprost (free acid form)

A member of the class of prostaglandins Falpha that is latanoprost free acid with a double bond at position 13.


leukotriene C3

A leukotriene that is (5S,7E,9E,11Z)-5-hydroxyicosa-7,9,11-trienoic acid in which a glutathionyl group is attached at position 6 via a sulfide linkage.


A hydroperoxyicosatrienoic acid that is (8Z,11Z,13E)-icosatrienoic acid in which the pro-S hydrogen at position 15 has been replaced by a hydroperoxy group.


A C20 hydroxy fatty acid having (5S)-, (6R)- and (15S)-hydroxy groups as well as (7E)- (9E)-, (11Z)- and (13E)-double bonds.


A DHET obtained by formal dihydroxylation across the 11,12-double bond of arachidonic acid.


20-hydroxy-6-trans-leukotriene B4

A member of the class of leukotrienes that is 6-trans-leukotriene B4 bearing an additional hydroxy substituent at position 20.


nonacosanoic acid

A very long-chain fatty acid comprising of 29 carbon atoms.


An EpETE obtained by formal epoxidation of the 11,12-double bond of all-cis-5,8,11,14,17-icosapentaenoic acid.


(S)-PGJ2-S-glutathione conjugate

A glutathione conjugate obtained by formal 1,4-addition of the thiol function of glutathione to the enone function of prostaglandin J2 (where the newly formed stereocentre at position 9 has S-configuration).


A 5-hydroperoxy-15-HETE stereoisomer that has 5S,15S configuration.


18-hydroxycarbocyclic thromboxane A2

A member of the class of thromboxanes that is carbocyclic thromboxane A2 carrying an additional hydroxy substituent at position 18.


prostaglandin E2-UM

A prostanoid that is prostaglandin E2 in which the acyclic hydroxy group has been oxidised to the corresponding ketone, the methyl group has been oxidised to the corresponding carboxylic acid and the 6-carboxyhexenyl group has been oxidatively cleaved to a 2-carboxyethyl group. It is the major urinary metabolite of prostaglandin E2.


An epoxy(hydroxy)icosatrienoic acid that is (5Z,8Z,11Z)-icosatrienoic acid having the epoxide group across positions 14-15 and the hydroxy substituent located at position 13.


18-hydroxyleukotriene B4

A leukotriene that is leukotriene B4 carrying an additional hydroxy substituent at position 18.


A leukotriene that is 10,11-dihydroleukotriene B4 in which the three methyl hydrogens at position 20 have been replaced by hydroxy groups.


15-dehydro-prostaglandin D2

The 15-dehydro derivative of prostaglandin D2.


An HETE that is (5Z,7E,11Z,14Z)-icosa-5,7,11,14-tetraenoic acid in which the hydroxy group is located at position 9.


A DHET obtained by formal dihydroxylation across the 5,6-double bond of arachidonic acid.


An epoxy(hydroxy)icosatrienoic acid consisting of (5Z,8Z,14Z)-icosa-5,9,14-trienoic acid having additional (10R)-hydroxy- and (11S,12S)-epoxy groups.


hydroperoxy(epoxy)icosatrienoic acid

An icosanoid derived from hydroperoxidation and epoxidation across one of the double bonds of arachidonic acid.


A hydroperoxy fatty acid that is (14S,15R)-epoxy-(5Z,9E,11Z)-icosatrienoic acid in which the hydroperoxy group is located at position 8S.


15-deoxy-Delta(12,14)-prostaglandin J3

A prostaglandin J derivative comprising prostaglandin J3 lacking the 15-hydroxy group and having C=C double bonds at the 12- and 14-positions. An intermediate of specialised proresolving mediators


prostaglandin H2 1-ethanolamide

An N-acylethanolamine compound formed by a condensation of prostaglandin H2 and ethanolamine.


prostaglandin F3alpha

A prostaglandin Falpha that is prosta-5,13,17-trien-1-oic acid carrying three hydroxy substituents at positions 9alpha, 11alpha and 15.


name: (1S,2R)-3-oxo-2-(2Z-pentenyl)cyclopentane-1-octanoic acid methyl ester


12-dehydro-leukotriene B4

A long-chain fatty acid consisting of leukotriene B4 having a 12-keto group in place of the 12-hydroxy group.


name: 7-[(1R,2R,3R)-3-hydroxy-2-(4-hydroxy-4-methyloct-1-enyl)-5-oxocyclopentyl]heptanoic acid methyl ester


PROSTAGLANDIN B1

A member of the class of prostaglandins B that is prosta-8(12),13-dien-1-oic acid carrying oxo and hydroxy substituents at positions 9 and 15 respectively (the 13E,15S-stereoisomer).


An icosanoid that is (6E,8Z,11Z,14Z,17Z)-icosapentaenoic acid carrying an oxo substituent at position 5. An intermediate of specialised proresolving mediators.


A HETE having an (8R)-hydroxy group and (5Z)-, (9E)-, (11Z)- and (14Z)-double bonds.


A hydroperoxy fatty acid that is (14S,15R)-epoxy-(5Z,8Z,10E)-icosatrienoic acid in which the hydroperoxy group is located at position 12S.


A prostanoid that is prostaglandin F2alpha  which is lacking two methylenes in the carboxyalkyl chain and in which the hydroxy group at position 15 has been oxidised to the corresponding ketone.


An EpETE obtained by formal epoxidation of the 14,15-double bond of all-cis-5,8,11,14,17-icosapentaenoic acid.


15-epi-lipoxin B4

A C20 hydroxy fatty acid having (5S)-, (14R)- and (15R)-hydroxy groups as well as (6E)- (8Z)-, (10E)- and (12E)-double bonds.


A 2-monoglyceride resulting from the condensation of the carboxy group of 15-deoxy-Delta(12,14)-prostaglandin J2 with the  hydroxy group at position 2 of glycerol.


20,20,20-trihydroxyleukotriene B4

A leukotriene that is leukotriene B4 in which the three methyl hydrogens at position 20 have been replaced by hydroxy groups.


prostaglandin G3

A member of the class of prostaglandins G that is 9,11-epidioxyprosta-5,13,17-trienoic acid carrying an additional hydroperoxy substituent at the 15S-position.


19-hydroxycarbocyclic thromboxane A2

A member of the class of thromboxanes that is carbocyclic thromboxane A2 carrying an additional hydroxy substituent at position 19.


name: (1S,2S)-3-oxo-2-(2Z-pentenyl)cyclopentane-1-octanoic acid methyl ester


An icosanoid that is (5Z,9E,14Z)-icosa-5,9,14-trienoic acid carrying four hydroxy substituents at positions 8, 11, 12 and 20. An intermediary metabolite from the 12(R)-lipoxygenase pathway.


An 18-HETE in which the 18-hydroxy group has R-configuration.


A 14,15-EET in which the epoxy moiety has 14S,15R-configuration.


latanoprost (free acid form)

A prostaglandin Falpha that is an analogue of prostaglandin F2alpha in which the pentyl group has been replaced by 2-phenylethyl and where the the 13,14-double bond has undergone formal hydrogenation. Its isopropyl ester prodrug, latanoprost, is used in the treatment of open-angle glaucoma and ocular hypertension.


A leukotriene with formula C23H39NO6S that results from the metabilism of leukotriene B4 by human keratinocytes.


HPETE

Mono-hydroperoxy (e)icosatetraenoic acids (HPETEs) are the primary products of lipoxygenase-catalysed oxygenation of arachidonic acid.


A member of the class of resolvins that is (6Z,8E,10E,14Z,16E)-icosapentaenoic acid carrying three hydroxy substituents at positions 5, 12, and 18R.


15-ketoprostaglandin F1alpha

A prostaglandin Falpha that is prostaglandin F1alpha bearing a keto substituent at the 15-position. It is the initial metabolite of prostaglandin F1alpha via 15-hydroxyprostaglandin dehydrogenase.


(17Z)-icosenoic acid

A 17-icosenoic acid in which the double bond adopts cis-configuration.


(18S)-hydroperoxyicosapentaenoic acid

A hydroperoxyicosapentaenoic acid that is an icosapentaenoic acid in which the pro-S hydrogen at position 18 has been replaced by a hydroperoxy group.


prostaglandin F2alpha 1-glyceryl ester

A 1-monoglyceride resulting from the condensation of the carboxy group of prostaglandin F2alpha with the 1-hydroxy group of glycerol.


A DiHETE consisting of arachidonic acid having the two hydroxy substituents located at position 17 and 18.


19-hydroxythromboxane A2

A thromboxane A that is thromboxane A2 carrying an additional hydroxy substituent at position 19.


An icosanoid that is any icosapentaenoic acid bearing hydroxy and hydroperoxy substituents. An oxidation product of icosapentaenoic acid metabolism.


An icosanoid that is leukotriene E4 in which the non-conjugated double bond has been reduced to a single bond and four methylene groups have been lost from the resulting carboxyalkyl chain.


name: (1S,2S)-3-oxo-2-pentylcyclopentane-1-octanoic acid methyl ester


name: 17-phenyl trinor-13,14-dihydro Prostaglandin A2


A DHET obtained by formal dihydroxylation across the 14,15-double bond of arachidonic acid.


18-oxoresolvin E1

A nonclassic icosanoid that is (6Z,8E,10E,14Z,16E)-icosa-6,8,10,14,16-pentaenoic acid carrying two hydroxy groups at positions 5 and 12 as well as an oxo group at position 18.


13,14-dihydro-15-oxoprostaglandin E1

A prostaglandin E obtained by formal oxidation of the 15-hydroxy group and hydrogenation of the 13,14-double bond of prostaglandin E1.


gadoleic acid

An icosenoic acid having a cis- double bond at position 9.


A leukotriene composed of (6E,8Z,10E,14Z)-icosatetraenoic acid having 5S- and 12R-hydroxy substituents.


An EpETE that is (5Z,9Z,11Z,14Z)-icosatetraenoic acid in which the epoxide function is located across positions 8 and 9.


The (S)-enantiomer of 12-HPETE.


name: (1S,2S)-3-oxo-2-pentylcyclopentane-1-hexanoic acid methyl ester


11,12-dihydro-12-oxoleukotriene C4

A leukotriene  that is (5S,7E,9E,14Z)-5-hydroxy-12-oxoicosa-7,9,14-trienoic acid to which a glutathionyl group is attached at position 6 via a sulfide linkage.


A HETE that is (5Z,8Z,11Z,13E)-15-hydroxyicosa-5,8,11,13-tetraenoic acid bearing a hydroxy substituent at position 15.


A (5Z,8Z,14Z)-11,12-dihydroxyicosatrienoic acid in which the two stereocentres at positions 11 and 12 both have S-configuration.


A 13-hydroxy-14,15-epoxy-(5Z,8Z,11Z)-icosatrienoic acid in which the chiral centres at positions 14 and 15 have R- and S-configuration respectively while that at position 13 remains unspecified.


name: (1S,2R)-3-oxo-2-(2Z-pentenyl)cyclopentane-1-hexanoic acid methyl ester


name: negative elongation factor B isoform m2 (mouse)

description: A negative elongation factor B (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8C4Y3-3.


name: UBC22_ARATH Ubiquitin-conjugating enzyme E2 22 (sprot)

description: A ubiquitin-conjugating enzyme E2 S that is encoded in the genome of Arabidopsis thaliana.


Brown-Vialetto-van Laere syndrome 1

description: Any Brown-Vialetto-van Laere syndrome in which the cause of the disease is a mutation in the SLC52A3 gene.


name: EPHA6_MOUSE Ephrin type-A receptor 6 (sprot)

description: An ephrin type-A receptor 6 that is encoded in the genome of mouse.


name: ephrin type-A receptor 6 isoform 1 (mouse)

description: An ephrin type-A receptor 6 isoform 1 that is encoded in the genome of mouse.


name: protein DBF4 homolog A isoform m1 (mouse)

description: A protein DBF4 homolog A (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9QZ41-1.


Pelvic girdle amyotrophy

description: Atrophy of the muscles of the pelvic girdle (also known as hip girdle), i.e., the gluteal muscles, the lateral rotators, the adductors, the psoas major and the iliacus muscle.


name: Amyotrophy of the musculature of the pelvis

description: Muscular atrophy affecting the muscles of the pelvis.


BNPS-skatole

A bromoindole that is 3H-indole in which the hydrogen at position 2 has been replaced by an (o-nitrophenyl)sulfanyl group and in which the hydrogens at position 3 have been replaced by a bromine and a methyl group. It is used particularly for the selective cleavage of tryptophanyl peptide bonds (cleavage occurs at peptide bonds after amino acids with available C(gamma)=C(delta) double bonds such as tryptophan, tyrosine, and histidine).


name: pro-cathepsin H glutathionylated 1 (human)

description: A pro-cathepsin H (human) that has been glutathionylated on the residue at the position equivalent to Cys-9 of the amino acid sequence represented by UniProtKB:P09668. UniProtKB:P09668, Cys-9, MOD:00234.


intravascular fasciitis

description: A rare self-limiting, rapidly growing, non-encapsulated benign neoplasm that arises from the vessels. It is characterized by the presence of plump spindle-shaped fibroblasts, multinucleated osteoclast-like giant cells, chronic inflammatory infiltrate, red blood cell extravasation, and high mitotic activity.


name: ILVC_BRUSI Ketol-acid reductoisomerase (NADP(+)) (sprot)

description: A ketol-acid reductoisomerase (NADP(+)) that is encoded in the genome of Brucella suis ATCC 23445.


Leg Cramp

description: An involuntary contraction of a muscle supporting the femur.


MRG/MORF4L-binding protein

A protein that is a translation product of the human MRGBP gene or a 1:1 ortholog thereof.


name: MRG/MORF4L-binding protein isoform m1 (mouse)

description: An MRG/MORF4L-binding protein (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9DAT2-1.


name: Q7K003_DROME MRG/MORF4L binding protein (trembl)

description: An MRG/MORF4L-binding protein that is encoded in the genome of fruit fly.


name: MRGBP_MOUSE MRG/MORF4L-binding protein (sprot)

description: An MRG/MORF4L-binding protein that is encoded in the genome of mouse.


name: MRG/MORF4L-binding protein isoform m2 (mouse)

description: An MRG/MORF4L-binding protein (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9DAT2-2.


name: MRGBP_HUMAN MRG/MORF4L-binding protein (sprot)

description: An MRG/MORF4L-binding protein that is encoded in the genome of human.


name: Q9FZD2_ARATH Chromatin modification-like protein (trembl)

description: An MRG/MORF4L-binding protein that is encoded in the genome of Arabidopsis thaliana.


name: GLGB2_ARATH 1,4-alpha-glucan-branching enzyme 2-2, chloroplastic/amyloplastic (sprot)

description: A protein that is a translation product of the SBE2.2 gene in Arabidopsis thaliana.


name: Sin3 histone deacetylase corepressor complex component SDS3, initiator methionine removed form (human)

description: A Sin3 histone deacetylase corepressor complex component SDS3 (human) that has had the initiator methionine removed. UniProtKB:Q9H7L9, 2-328.


name: Sin3 histone deacetylase corepressor complex component SDS3, initiator methionine removed ubiquitinated form (human)

description: A Sin3 histone deacetylase corepressor complex component SDS3 (human) that has had the initiator methionine removed and that includes at least one ubiquitinated lysine. UniProtKB:Q9H7L9, 2-328, MOD:01148.


name: prolyl endopeptidase-like isoform r1 (rat)

description: A prolyl endopeptidase-like (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q5HZA6-1.


name: HIPPO_DROME Serine/threonine-protein kinase hippo (sprot)

description: A protein that is a translation product of the hpo gene in fruit fly.


name: Stage IV Major Salivary Gland Carcinoma with Metastasis

description: Stage IV carcinoma of the major salivary glands with regional lymph nodes and/or distant metastases.


teneurin-3 isoform mA2B1 (mouse)

A teneurin-3 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9WTS6-5.


name: dual specificity protein phosphatase 13B isoform h5 (human)

description: A dual specificity protein phosphatase 13B (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9UII6-5.


Cervical Micropapillary Adenocarcinoma

description: A rare, invasive adenocarcinoma that arises from the cervix and is characterized by a micropapillary architecture.


calcitriol 25-O-(beta-D-glucuronide)

A steroid glucosiduronic acid that is calcitriol in which the hydroxy hydrogen at position 25 has been replaced by a beta-D-glucuronyl residue.


uromodulin N-glycosylated 357 (human)

A uromodulin (human) that has been N-glycosylated at the residue equivalent to Asn-76 of the amino acid sequence represented by UniProtKB:P07911-1, in which the glycan structure is represented by GlyTouCan:G79565XA. Example: UniProtKB:P07911-1, Asn-76, MOD:00160~GNO:G79565XA.


Late Stillbirth

description: Delivery of a dead fetus greater than 28 weeks gestational age and/or greater than 1,000 grams birth weight.


An organic sulfide that consists of two 4-hydroxybenzyl groups covalently bound to a central sulfur atom. It is isolated from Gastrodia elata and Pleuropterus ciliinervis and exhibits neoroprotective activity.


name: laminin subunit beta-1 methylated 1 (human)

description: A laminin subunit beta-1 (human) that has been methylated on the residue at the position equivalent to Cys-1009 of the amino acid sequence represented by UniProtKB:P07942. UniProtKB:P07942, Cys-1009, MOD:00660.


name: ETS translocation variant 4 isoform m2 (mouse)

description: An ETS translocation variant 4 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P28322-2.


name: TPIS_CHICK Triosephosphate isomerase (sprot)

description: A triosephosphate isomerase that is encoded in the genome of chicken.


name: torsin-1A-interacting protein 1 isoform h3 (human)

description: A torsin-1A-interacting protein 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q5JTV8-3.


chaperedoxin

A protein that is a translation product of the Escherichia coli K-12 ybbN gene or a 1:1 ortholog thereof.


CNOX_ECOLI Chaperedoxin (sprot)

A chaperedoxin that is encoded in the genome of Escherichia coli K-12.


name: Pathologic Stage IVB Gastroesophageal Junction Adenocarcinoma AJCC v8

description: Stage IVB includes: Any T, Any N, M1, Any G. M1: Distant metastasis. (AJCC 8th ed.)


name: Gastroesophageal Junction Adenocarcinoma by AJCC v8 Pathologic Stage

description: A term that refers to the pathologic staging of gastroesophageal junction adenocarcinoma according to the American Joint Committee on Cancer, 8th edition.


name: Pathologic Stage IIIB Gastroesophageal Junction Adenocarcinoma AJCC v8

description: Stage IIIB includes: (T2, N2, M0, Any G); (T3, N1-2, M0, Any G); (T4a, N0-1, M0, Any G). T2: Tumor invades the muscularis propria. T3: Tumor invades adventitia. T4a: Tumor invades the pleura, pericardium, azygos vein, diaphragm, or peritoneum. N0: No regional lymph node metastasis. N1: Tumor with metastasis in one or two regional lymph nodes. N2: Tumor with metastasis in three to six regional lymph nodes. M0: No distant metastasis. (AJCC 8th ed.)


name: Pathologic Stage IA Gastroesophageal Junction Adenocarcinoma AJCC v8

description: Stage IA includes: (T1a, N0, M0, G1); (T1a, N0, M0, GX). T1a: Tumor invades the lamina propria or muscularis mucosae. N0: No regional lymph node metastasis. M0: No distant metastasis. G1: Well-differentiated. GX: Grade cannot be assessed. (AJCC 8th ed.)


name: Pathologic Stage IIIA Gastroesophageal Junction Adenocarcinoma AJCC v8

description: Stage IIIA includes: (T1, N2, M0, Any G); (T2, N1, M0, Any G). T1: Tumor invades the lamina propria, muscularis mucosae, or submucosa. T2: Tumor invades the muscularis propria. N1: Tumor with metastasis in one or two regional lymph nodes. N2: Tumor with metastasis in three to six regional lymph nodes. M0: No distant metastasis. (AJCC 8th ed.)


name: Pathologic Stage 0 Gastroesophageal Junction Adenocarcinoma AJCC v8

description: Stage 0 includes: Tis, N0, M0, GN/A. Tis: High-grade dysplasia, defined as malignant cells confined to the epithelium by the basement membrane. N0: No regional lymph node metastasis. M0: No distant metastasis. GN/A: Grade non-applicable. (AJCC 8th ed.)


name: Pathologic Stage IIA Gastroesophageal Junction Adenocarcinoma AJCC v8

description: Stage IIA includes: (T2, N0, M0, G3); (T2, N0, M0, GX). T2: Tumor invades the muscularis propria. N0: No regional lymph node metastasis. M0: No distant metastasis. GX: Grade cannot be assessed. G3: Poorly differentiated, undifferentiated. (AJCC 8th ed.)


name: Pathologic Stage I Gastroesophageal Junction Adenocarcinoma AJCC v8

description: Stage I includes: IA: (T1a, N0, M0, G1); (T1a, N0, M0, GX); IB: (T1a, N0, M0, G2); (T1b, N0, M0, G1-2); (T1b, N0, M0, GX); IC: (T1, N0, M0, G3); (T2, N0, M0, G1-2). T1a: Tumor invades the lamina propria or muscularis mucosae. T1b: Tumor invades the submucosa. T1: Tumor invades the lamina propria, muscularis mucosae, or submucosa. T2: Tumor invades the muscularis propria. N0: No regional lymph node metastasis. M0: No distant metastasis. G1: Well-differentiated. GX: Grade cannot be assessed. G2: Moderately differentiated. G3: Poorly differentiated, undifferentiated. (AJCC 8th ed.)


name: Pathologic Stage II Gastroesophageal Junction Adenocarcinoma AJCC v8

description: Stage II includes: IIA: (T2, N0, M0, G3); (T2, N0, M0, GX); IIB: (T1, N1, M0, Any G); (T3, N0, M0, Any G). T2: Tumor invades the muscularis propria. T1: Tumor invades the lamina propria, muscularis mucosae, or submucosa. T3: Tumor invades adventitia. N0: No regional lymph node metastasis. N1: Tumor with metastasis in one or two regional lymph nodes. M0: No distant metastasis. GX: Grade cannot be assessed. G3: Poorly differentiated, undifferentiated. (AJCC 8th ed.)


name: Pathologic Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8

description: Stage III includes: IIIA: (T1, N2, M0, Any G); (T2, N1, M0, Any G); IIIB: (T2, N2, M0, Any G); (T3, N1-2, M0, Any G); (T4a, N0-1, M0, Any G). T1: Tumor invades the lamina propria, muscularis mucosae, or submucosa. T2: Tumor invades the muscularis propria. T3: Tumor invades adventitia. T4a: Tumor invades the pleura, pericardium, azygos vein, diaphragm, or peritoneum. N0: No regional lymph node metastasis. N1: Tumor with metastasis in one or two regional lymph nodes. N2: Tumor with metastasis in three to six regional lymph nodes. M0: No distant metastasis. (AJCC 8th ed.)


name: Pathologic Stage IC Gastroesophageal Junction Adenocarcinoma AJCC v8

description: Stage IC includes: (T1, N0, M0, G3); (T2, N0, M0, G1-2). T1: Tumor invades the lamina propria, muscularis mucosae, or submucosa. T2: Tumor invades the muscularis propria. N0: No regional lymph node metastasis. M0: No distant metastasis. G1: Well-differentiated. G2: Moderately differentiated. G3: Poorly differentiated, undifferentiated. (AJCC 8th ed.)


name: Pathologic Stage IVA Gastroesophageal Junction Adenocarcinoma AJCC v8

description: Stage IVA includes: (T4a, N2, M0, Any G); (T4b, N0-2, M0, Any G); (Any T, N3, M0, Any G). T4a: Tumor invades the pleura, pericardium, azygos vein, diaphragm, or peritoneum. T4b: Tumor invades other adjacent structures, such as the aorta, vertebral body, or airway. N0: No regional lymph node metastasis. N1: Tumor with metastasis in one or two regional lymph nodes. N2: Tumor with metastasis in three to six regional lymph nodes. N3: Tumor with metastasis in seven or more regional lymph nodes. M0: No distant metastasis. (AJCC 8th ed.)


name: Pathologic Stage IIB Gastroesophageal Junction Adenocarcinoma AJCC v8

description: Stage IIB includes: (T1, N1, M0, Any G); (T3, N0, M0, Any G). T1: Tumor invades the lamina propria, muscularis mucosae, or submucosa. T3: Tumor invades adventitia. N0: No regional lymph node metastasis. N1: Tumor with metastasis in one or two regional lymph nodes. M0: No distant metastasis. (AJCC 8th ed.)


name: Pathologic Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8

description: Stage IV includes: IVA: (T4a, N2, M0, Any G); (T4b, N0-2, M0, Any G); (Any T, N3, M0, Any G); IVB: (Any T, Any N, M1, Any G). T4a: Tumor invades the pleura, pericardium, azygos vein, diaphragm, or peritoneum. T4b: Tumor invades other adjacent structures, such as the aorta, vertebral body, or airway. N0: No regional lymph node metastasis. N1: Tumor with metastasis in one or two regional lymph nodes. N2: Tumor with metastasis in three to six regional lymph nodes. N3: Tumor with metastasis in seven or more regional lymph nodes. M0: No distant metastasis. M1: Distant metastasis. (AJCC 8th ed.)


name: Pathologic Stage IB Gastroesophageal Junction Adenocarcinoma AJCC v8

description: Stage IB includes: (T1a, N0, M0, G2); (T1b, N0, M0, G1-2); (T1b, N0, M0, GX). T1a: Tumor invades the lamina propria or muscularis mucosae. T1b: Tumor invades the submucosa. N0: No regional lymph node metastasis. M0: No distant metastasis. G1: Well-differentiated. GX: Grade cannot be assessed. G2: Moderately differentiated. (AJCC 8th ed.)


name: YDCZ_ECOLI Inner membrane protein YdcZ (sprot)

description: An inner membrane protein YdcZ that is encoded in the genome of Escherichia coli K-12.


name: Refractory High Grade Burkitt-Like Lymphoma

description: High grade B-cell lymphoma Burkitt-like lymphoma resistant to treatment.


name: Recurrent High Grade Burkitt-Like Lymphoma

description: The reemergence of high grade B-cell lymphoma Burkitt-like lymphoma after a period of remission.


name: Stage II High Grade Adult Non-Hodgkin's Lymphoma


name: Stage II High Grade Burkitt-Like Lymphoma

description: Stage II NHL means involvement of two or more lymph node regions on the same side of the diaphragm (II) or localized involvement of a single associated extralymphatic organ or site and its regional lymph nodes with or without other lymph node regions on the same side of the diaphragm (IIE). Note: The number of lymph node regions involved may be indicated by a subscript (e.g., II3). (from PDQ)


name: High Grade B-Cell Non-Hodgkin's Lymphoma


name: Stage I High Grade Burkitt-Like Lymphoma

description: Stage I NHL means involvement of a single lymph node region (I) or localized involvement of a single extralymphatic organ or site (IE). (from PDQ)


name: Recurrent High Grade Adult Non-Hodgkin's Lymphoma


name: Stage IV High Grade Adult Non-Hodgkin's Lymphoma


name: Stage IV High Grade Burkitt-Like Lymphoma

description: Stage IV NHL means disseminated (multifocal) involvement of one or more extralymphatic sites with or without associated lymph node involvement or isolated extralymphatic organ involvement with distant (nonregional) nodal involvement. (from PDQ)


name: Stage III High Grade Adult Non-Hodgkin's Lymphoma


name: Stage I High Grade Adult Non-Hodgkin's Lymphoma


name: Stage III High Grade Burkitt-Like Lymphoma

description: Stage III NHL means involvement of lymph node regions on both sides of the diaphragm (III) that may also be accompanied by localized involvement of an extralymphatic organ or site (IIIE), by involvement of the spleen (IIIS), or both (IIIS+E). (from PDQ)


High Grade Burkitt-Like Lymphoma

description: A high grade B-cell lymphoma showing greater pleomorphism in nuclear size and shape than the classical Burkitt lymphoma.


allocholic acid

An allo-bile acid that is 5alpha-cholan-24-oic acid bearing three alpha-hydroxy substituents at position 3, 7 and 12.


name: Muellerian-inhibiting factor isoform 1 cleaved and glycosylated form

description: A Muellerian-inhibiting factor isoform 1 cleaved 1 that includes at least one glycosylated residue.


name: Muellerian-inhibiting factor isoform 1 cleaved and glycosylated 2

description: A Muellerian-inhibiting factor isoform 1 cleaved and glycosylated form that has been cleaved at the RxxR dibasic cleavage site rendering the propeptide and the mature protein non-covalently bound.


name: Muellerian-inhibiting factor isoform 1 cleaved and N-glycosylated 2 (human)

description: A Muellerian-inhibiting factor isoform 1 cleaved and glycosylated 2 in human, in which the cleaved parts remain joined by disulfide bonds. The position(s) of glycosylation sites have not been experimentally determined. UniProtKB:P03971-1, 26-450, 451-560, MOD:00160.


name: Patchy sclerosis of the proximal phalanx of the 3rd toe


name: NLTP1_ARATH Non-specific lipid-transfer protein 1 (sprot)

description: A protein that is a translation product of the LTP1 gene in Arabidopsis thaliana.


name: Macroscopically Positive Parametrial Margin

description: The presence of macroscopically visible residual tumor in surgical margins in the parametrial region.


name: FCERA_MOUSE High affinity immunoglobulin epsilon receptor subunit alpha (sprot)

description: A high affinity immunoglobulin epsilon receptor subunit alpha that is encoded in the genome of mouse.


name: NU116_YEAST Nucleoporin NUP116/NSP116 (sprot)

description: A protein that is a translation product of the NUP116 gene in yeast.


name: CAT1_SCHPO Cationic amino acid transporter 1 (sprot)

description: A protein that is a translation product of the cat1 gene in Schizosaccharomyces pombe 972h-.


name: Stage IVB Esophageal Squamous Cell Carcinoma


name: sodium/nucleoside cotransporter 1 isoform h2 (human)

description: A sodium/nucleoside cotransporter 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O00337-2.


name: lactotransferrin, signal peptide removed form (human)

description: A lactotransferrin (human) that has had the signal peptide removed. UniProtKB:P02788, 20-710.


chronic sphenoidal sinusitis

description: Inflammation of the sphenoid sinus that typically lasts beyond eight weeks. It is caused by infections, allergies, and the presence of sinus polyps or a deviated septum. Signs and symptoms include headache, nasal discharge, swelling in the face, dizziness, and breathing difficulties.


name: band 4.1-like protein 3 isoform m3 (mouse)

description: A band 4.1-like protein 3 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9WV92-3.


name: 1alpha,25-dihydroxy-2beta-(2-hydroxyethoxy)vitamin D3 / 1alpha,25-dihydroxy-2beta-(2-hydroxyethoxy)cholecalciferol


cuticle collagen 6 isoform a (worm)

A cuticle collagen 6 (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P18831-1.


name: serine/threonine-protein kinase Kist methylated 2 (human)

description: A serine/threonine-protein kinase Kist (human) that has been methylated on the residue at the position equivalent to Cys-207 of the amino acid sequence represented by UniProtKB:Q8TAS1-1. Example: UniProtKB:Q8TAS1-1, Cys-207, MOD:00660.


name: N-[6-[2-[(6-methoxy-2-quinolinyl)methylidene]hydrazinyl]-6-oxohexyl]carbamic acid tert-butyl ester


name: Type 2 diabetes mellitus with ketoacidosis, with coma

description: Evidence of type 2 diabetes mellitus with ketoacidosis with coma.


PHOSPHOCHOLINE

The phosphate of choline; and the parent compound of the phosphocholine family.


name: ATP-dependent RNA helicase DHX15 isoform 1 (human)

description: An ATP-dependent RNA helicase DHX15 isoform 1 that is encoded in the genome of human.


protein DPCD isoform r2 (rat)

A protein DPCD (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q6AYM4-2.


name: short transient receptor potential channel 6 isoform h1 (human)

description: A short transient receptor potential channel 6 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9Y210-1.


name: short transient receptor potential channel 6

description: A transient receptor potential cation channel TRPC3/6/7 that is a translation product of the human TRPC6 gene or a 1:1 ortholog thereof.


name: short transient receptor potential channel 6 isoform h3 (human)

description: A short transient receptor potential channel 6 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9Y210-3.


name: short transient receptor potential channel 6 phosphorylated 1 (human)

description: A short transient receptor potential channel 6 (human) that has been phosphorylated on the residue at the position equivalent to Thr-402 of the amino acid sequence represented by UniProtKB:Q9Y210-1. Example: UniProtKB:Q9Y210-1, Thr-402, MOD:00047.


name: TRPC6_MOUSE Short transient receptor potential channel 6 (sprot)

description: A short transient receptor potential channel 6 that is encoded in the genome of mouse.


name: TRPC6_HUMAN Short transient receptor potential channel 6 (sprot)

description: A short transient receptor potential channel 6 that is encoded in the genome of human.


name: short transient receptor potential channel 6 N-glycosylated 2 (human)

description: A short transient receptor potential channel 6 (human) that has been N-glycosylated at the residue equivalent to Asn-473 of the amino acid sequence represented by UniProtKB:Q9Y210-1, in which the glycan composition is represented by GlyTouCan:G12580WI. Example: UniProtKB:Q9Y210-1, Asn-473, MOD:00160~GNO:G12580WI.


name: short transient receptor potential channel 6 N-glycosylated 1 (human)

description: A short transient receptor potential channel 6 (human) that has been N-glycosylated at the residue equivalent to Asn-473 of the amino acid sequence represented by UniProtKB:Q9Y210-1, in which the glycan composition is represented by GlyTouCan:G08293MJ. Example: UniProtKB:Q9Y210-1, Asn-473, MOD:00160~GNO:G08293MJ.


name: short transient receptor potential channel 6 isoform h2 (human)

description: A short transient receptor potential channel 6 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9Y210-2.


Benign Nasolacrimal Duct Neoplasm

description: A neoplasm that arises from the lacrimal duct and is characterized by the absence of atypical or malignant cytological and architectural features, and absence of invasive features or metastatic potential.


name: Hodgkin lymphoma, nodular sclerosis, cellular phase

description: A nodular sclerosis Hodgkin lymphoma characterized by the presence of lacunar cells, nodular growth, and the absence of fibrosis.


name: OR5M5_MOUSE Olfactory receptor 5M5 (sprot)

description: An olfactory receptor 5M5 that is encoded in the genome of mouse.


olfactory receptor 5M5

A protein that is a translation product of the mouse Olfr1030 gene or a 1:1 ortholog thereof.


name: HYDN_ECOLI Electron transport protein HydN (sprot)

description: An electron transport protein HydN that is encoded in the genome of Escherichia coli K-12.


electron transport protein HydN

A protein that is a translation product of the Escherichia coli K-12 hydN gene or a 1:1 ortholog thereof.


name: proenkephalin-A proteolytic cleavage product

description: A proenkephalin-A that has been processed by proteolytic cleavage.


Non Progressive Disease

description: Following a previous assessment of progressive disease unconfirmed (PDu) of non-target lesion(s), the subsequent required assessment does not confirm progressive disease.


name: pre-mRNA 3' end processing protein pfs-2 isoform b (worm)

description: A pre-mRNA 3' end processing protein pfs-2 (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:U4PCM1-2.


name: TNNC1_HUMAN Troponin C, slow skeletal and cardiac muscles (sprot)

description: A troponin C, slow skeletal and cardiac muscles that is encoded in the genome of human.


name: troponin C, slow skeletal and cardiac muscles isoform 1 (human)

description: A troponin C, slow skeletal and cardiac muscles isoform 1 that is encoded in the genome of human.


name: uncharacterized HTH-type transcriptional regulator YidP

description: A protein that is a translation product of the Escherichia coli K-12 yidP gene or a 1:1 ortholog thereof.


name: YIDP_ECOLI Uncharacterized HTH-type transcriptional regulator YidP (sprot)

description: An uncharacterized HTH-type transcriptional regulator YidP that is encoded in the genome of Escherichia coli K-12.


LEXA_BACSU LexA repressor (sprot)

A LexA repressor that is encoded in the genome of Bacillus subtilis subsp. subtilis str. 168.


name: CML2_ARATH Calmodulin-like protein 2 (sprot)

description: A protein that is a translation product of the CML2 gene in Arabidopsis thaliana.


name: ATP-binding cassette sub-family C member 12 isoform h1 (human)

description: An ATP-binding cassette sub-family C member 12 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q96J65-1.


An imidazolidine-2,4-dione substituted by a guanidino group at position 5.


name: Unresectable Cervical Adenosquamous Carcinoma

description: Cervical adenosquamous carcinoma that is not amenable to surgical resection.


name: uncharacterized protein ZK688.5 isoform a (worm)

description: An uncharacterized protein ZK688.5 (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P34675-1.


name: YO25_CAEEL Uncharacterized protein ZK688.5 (sprot)

description: A protein that is a translation product of the ZK688.5 gene in worm.


name: uncharacterized protein ZK688.5 isoform b (worm)

description: An uncharacterized protein ZK688.5 (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P34675-2.


name: squamosa promoter-binding-like protein 7 isoform 2 (Arabidopsis thaliana)

description: A squamosa promoter-binding-like protein 7 (Arabidopsis thaliana) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8S9G8-2.


pyripyropene L

A sesquiterpenoid that consists of a heterotetracyclic system linked to a pyridine moiety. Isolated from the fungus, Aspergillus fumigatus, it exhibits inhibitory activity against acyl-CoA:cholesterol acyltransferase 2.


name: KC1A_CHICK Casein kinase I isoform alpha (sprot)

description: A casein kinase I isoform alpha that is encoded in the genome of chicken.


name: casein kinase I isoform alpha isoform CK1A-L (chicken)

description: A casein kinase I isoform alpha isoform 2 that is encoded in the genome of chicken.


name: casein kinase I isoform alpha isoform CK1A (chicken)

description: A casein kinase I isoform alpha isoform 1 that is encoded in the genome of chicken.


name: casein kinase I isoform alpha isoform CK1A-LS (chicken)

description: A casein kinase I isoform alpha (chicken) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P67962-3.


name: negative elongation factor A, initiator methionine removed form

description: A negative elongation factor A that has had the initiator methionine removed.


name: Sec1 family domain-containing protein 2 isoform 1 (human)

description: A Sec1 family domain-containing protein 2 isoform 1 that is encoded in the genome of human.


name: DHYS_HUMAN Deoxyhypusine synthase (sprot)

description: A deoxyhypusine synthase that is encoded in the genome of human.


name: deoxyhypusine synthase methylated 1 (human)

description: A deoxyhypusine synthase (human) that has been methylated on the residue at the position equivalent to Cys-275 of the amino acid sequence represented by UniProtKB:P49366-1. Example: UniProtKB:P49366-1, Cys-275, MOD:00660.


name: deoxyhypusine synthase isoform Long (human)

description: A deoxyhypusine synthase isoform 1 that is encoded in the genome of human.


name: deoxyhypusine synthase isoform Short (human)

description: A deoxyhypusine synthase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P49366-2.


name: deoxyhypusine synthase isoform h3 (human)

description: A deoxyhypusine synthase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P49366-3.


name: deoxyhypusine synthase deaminated 1 (human)

description: A deoxyhypusine synthase (human) that has been deaminated on the residue at the position equivalent to Asn-294 of the amino acid sequence represented by UniProtKB:P49366-1. Example: UniProtKB:P49366-1, Asn-294, MOD:00684.


pyrin domain-containing protein 1

A protein that is a translation product of the human PYDC1 gene or a 1:1 ortholog thereof.


name: PYDC1_HUMAN Pyrin domain-containing protein 1 (sprot)

description: A pyrin domain-containing protein 1 that is encoded in the genome of human.


name: coiled-coil domain-containing protein 60

description: A protein that is a translation product of the human CCDC60 gene or a 1:1 ortholog thereof.


name: CCD60_HUMAN Coiled-coil domain-containing protein 60 (sprot)

description: A coiled-coil domain-containing protein 60 that is encoded in the genome of human.


name: CCD60_MOUSE Coiled-coil domain-containing protein 60 (sprot)

description: A coiled-coil domain-containing protein 60 that is encoded in the genome of mouse.


name: coiled-coil domain-containing protein 60 isoform m1 (mouse)

description: A coiled-coil domain-containing protein 60 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8C4J0-1.


name: coiled-coil domain-containing protein 60 isoform m2 (mouse)

description: A coiled-coil domain-containing protein 60 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8C4J0-2.


name: CCD60_RAT Coiled-coil domain-containing protein 60 (sprot)

description: A coiled-coil domain-containing protein 60 that is encoded in the genome of rat.


protein unc-33 isoform a (worm)

A protein unc-33 (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q01630-1.


UNC33_CAEEL Protein unc-33 (sprot)

A protein that is a translation product of the unc-33 gene in worm.


protein unc-33 isoform c (worm)

A protein unc-33 (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q01630-3.


protein unc-33 isoform b (worm)

A protein unc-33 (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q01630-2.


name: splicing factor 3B subunit 3 isoform h3 (human)

description: A splicing factor 3B subunit 3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q15393-3.


name: E3 ubiquitin-protein ligase MBR1 isoform 1 (Arabidopsis thaliana)

description: An E3 ubiquitin-protein ligase MBR1 (Arabidopsis thaliana) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9ZQF9-1.


name: cyclin-dependent kinase 2-interacting protein isoform m2 (mouse)

description: A cyclin-dependent kinase 2-interacting protein (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9D0V8-2.


Urogenital fistula

description: The presence of a fistula affecting the genitourinary system.


Rectoperineal fistula

description: The presence of a fistula between the perineum and the rectum.


Urethrovaginal fistula

description: The presence of a fistula between the vagina and the urethra.


H-type rectovestibular fistula

description: Rectovestibular fistula with a normal anus is known as H-type fistula or double termination of the alimentary tract.


Perineal fistula

description: The presence of a fistula between the bowel and the perineum.


Anoperineal fistula

description: The presence of a fistula (abnormal tunnel) between the anal canal and the perineum.


Vaginal fistula

description: The presence of a fistula of the vagina.


Urachus fistula

description: Persistence of the urachal canal with drainage of urine from the bladder through the persistent allantois canal to the umbilicus.


Rectourethral fistula

description: An abnormal connection (fistula) between the rectum and the urethra.


Rectovaginal fistula

description: The presence of a fistula between the vagina and the rectum.


Rectoureteral fistula

description: An abnormal connection (fistula) between the rectum and the ureter.


Rectovestibular fistula

description: A congenital malformation characterized by an abnormal connection (fistula) between the rectum and the vulval vestibule, at the lower aspect of the vaginal opening.


Rectal fistula

description: The presence of a fistula affecting the rectum.


Colovesical fistula

description: An aberrant, pathological communication between the colon and the bladder.


Urethral fistula

description: The presence of an abnormal connection between the urethra and another organ or the skin.


Rectovesical fistula

description: An aberrant, pathological communication between the rectum and the bladder.


Grade 5 Pulmonary Hypertension, CTCAE

description: Death


A sialodiosylceramide that consists of an alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->4)-beta-D-Glc moiety attached via a glycosidic bond at position 1 of N-acylicosasphingosine.


name: DBIRD complex subunit ZNF326 isoform h3 (human)

description: A DBIRD complex subunit ZNF326 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q5BKZ1-3.


name: OSG1_CAEEL Rho guanine nucleotide exchange factor osg-1 (sprot)

description: A protein that is a translation product of the osg-1 gene in worm.


name: homeobox protein SIX3 isoform mSIX3B (mouse)

description: A homeobox protein SIX3 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q62233-1.


name: SIX3_MOUSE Homeobox protein SIX3 (sprot)

description: A homeobox protein SIX3 that is encoded in the genome of mouse.


name: homeobox protein SIX3 isoform mSIX3A (mouse)

description: A homeobox protein SIX3 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q62233-2.


diacylglycerol 35:2

A diglyceride in which the two acyl groups contain a total of 35 carbons and 2 double bonds.


name: protein phosphatase 1 regulatory subunit 3C isoform 1 (human)

description: A protein phosphatase 1 regulatory subunit 3C isoform 1 that is encoded in the genome of human.


name: PUB36_ARATH U-box domain-containing protein 36 (sprot)

description: A protein that is a translation product of the PUB36 gene in Arabidopsis thaliana.


name: U-box domain-containing protein 36 isoform 1 (Arabidopsis thaliana)

description: A U-box domain-containing protein 36 (Arabidopsis thaliana) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8GZ84-1.


name: electrogenic sodium bicarbonate cotransporter 1 isoform 1

description: An electrogenic sodium bicarbonate cotransporter 1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9Y6R1-1 or a 1:1 ortholog thereof.


name: electrogenic sodium bicarbonate cotransporter 1 isoform 1 (mouse)

description: An electrogenic sodium bicarbonate cotransporter 1 isoform 1 that is encoded in the genome of mouse.


name: electrogenic sodium bicarbonate cotransporter 1 isoform 1 (rat)

description: An electrogenic sodium bicarbonate cotransporter 1 isoform 1 that is encoded in the genome of rat.


name: electrogenic sodium bicarbonate cotransporter 1 isoform 1 (human)

description: An electrogenic sodium bicarbonate cotransporter 1 isoform 1 that is encoded in the genome of human.


Leu-Val-Ser

A tripeptide composed of L-leucine, L-valine and L-serine joined in sequence by peptide linkages.