Absent Morphologic Response

description: The absence of change in the overall attenuation of the metastasis and in the peripheral rim, suggesting a lack of response to treatment.


Bladder Cancer TNM Finding v8

category: biolink:PhenotypicFeature biolink:DiseaseOrPhenotypicFeature biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing

description: A finding about one or more characteristics of bladder cancer, following the rules of the TNM AJCC v8 classification system. This classification system applies to carcinomas arising in the bladder. The typical carcinoma of the bladder is urothelial carcinoma. These carcinomas may include other histologic elements, including adenocarcinoma, squamous cell carcinoma, and small cell neuroendocrine carcinoma, but should be classified as urothelial unless the cancer is composed entirely of the alternative histology. All histologic cell types that are derived primarily from the urinary bladder epithelium should follow this classification system. It does not apply to prostatic urothelial carcinomas (are staged according to the classification for urethra), lymphomas (are staged according to the classification for Hodgkin and non-Hodgkin lymphoma), and sarcomas (are staged according to the classification for soft tissue sarcoma of the abdomen and thoracic visceral organs).  (from AJCC 8th Ed.)


Lumbar Meningocele

category: biolink:Disease biolink:DiseaseOrPhenotypicFeature biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing

description: A congenital abnormality in the lumbar region of the spine in which the meninges protrude through a defect in the spinal column.


name: Small Cell B-Cell Lymphoma, Intrathoracic Lymph Nodes

description: Evidence of small cell B-cell lymphoma in the intrathoracic lymph nodes.


name: Metastatic Extrapulmonary Large Cell Neuroendocrine Carcinoma

description: Extrapulmonary large cell neuroendocrine carcinoma that has spread to another anatomic site.


name: Grade 4 Bone Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


Grade 2 Venous Injury, CTCAE

description: Symptomatic (e.g., claudication); repair or revision not indicated


name: Other Atherosclerosis of Unspecified Type of Bypass Graft(s) of the Extremities, Right Leg

description: Evidence of other atherosclerosis of unspecified type of bypass graft(s) of the extremities in the right leg not specified elsewhere.


name: Clinical Stage 0 Cutaneous Melanoma AJCC v8

description: Stage 0 includes: Tis, N0, M0. Tis: Melanoma in situ. Thickness: Not applicable. Ulceration status: Not applicable. N0: No regional lymph node metastasis detected. Presence of in-transit, satellite, and/or microsatellite metastases: No. M0: No evidence of distant metastasis. LDH level is not applicable. (AJCC 8th ed.)


Oropharyngeal candidiasis

description: Infection of the oropharynx with, or disease caused by, Candida, especially C. albicans. This disease usually results from debilitation (as in immunosuppression and especially AIDS), physiologic change, prolonged administration of antibiotics, and iatrogenic and barrier breakage. SYN candidosis, moniliasis.


name: Non-Hodgkin Lymphoma, Lymph Nodes of Axilla and Upper Limb

description: Evidence of non-Hodgkin lymphoma in the lymph nodes of axilla and upper limb.


name: Unresectable Genitourinary System Carcinoma

description: Genitourinary system carcinoma that is not amenable to surgical resection.


Postoperative infection

description: Any infection documented following a surgical procedure that was not evident or suspected prior to the procedure.


Primary Cutaneous Mucinous Carcinoma

description: A rare low-grade carcinoma of the sweat glands. The most common sites are eyelids, scalp, axilla, face and trunk. It is histologically characterized by proliferating ducts until the overproduction of mucin creates islands of tumor cells, essentially floating in mucinous pools (Rosai J. Ackerman's Surgical Pathology).


name: Unresectable Vulvar Squamous Cell Carcinoma

description: Vulvar squamous cell carcinoma that is not amenable to surgical resection.


Grade 2 Colonic Perforation, CTCAE

description: Invasive intervention not indicated


name: Grade 5 Small Intestinal Mucositis, CTCAE

description: Death


Rapid Virologic Response

description: A finding of aviremia at a specified timepoint, early during the treatment period.


name: Atherosclerosis of Native Arteries of Extremities with Rest Pain, Right Leg

description: Evidence of atherosclerosis of native arteries of extremities with rest pain in the right leg.


name: Nasopharyngeal Cancer pT1 TNM Finding v6

description: Nasopharyngeal cancer with tumor confined to the nasopharynx. (from AJCC 6th Ed.)


Toxic nephropathy

description: Toxicity that impairs or damages the kidney. This condition is often caused by the administration of a pharmaceutical agent that causes damage to the kidney.


Grade 2 Pharyngeal Hemorrhage, CTCAE

description: Moderate symptoms; intervention indicated


Lupus encephalitis

description: Encephalitis that is associated with systemic lupus erythematosus.


name: Malignant Neoplasm of Right Fallopian Tube

description: Evidence of a malignant neoplasm of the right fallopian tube.


Childhood depression

description: Similar to depression in adults, childhood depression is characterized by a prolonged depressed or irritable mood accompanied by a significant loss of interest in activities, changes in appetite or sleep, decreased energy, feelings of worthlessness, and/or recurrent thoughts of death or suicide.


Adult Astroblastoma, MN1-Altered

description: An astroblastoma, MN1-altered that occurs during adulthood.


Cervical Cancer pN1 TNM Finding v8

description: Cervical cancer with regional lymph node metastasis. (from AJCC 8th Ed.)


name: Bone Cancer Pathologic Primary Tumor TNM Finding v7

description: A pathologic finding about one or more characteristics of bone cancer, following the rules of the TNM AJCC v7 classification system as they pertain to staging of the primary tumor.


name: Grade 5 Radiation Excluding Chemoradiation, CTCAE


Grade 3 Ovarian Rupture, CTCAE

description: Transfusion; invasive intervention indicated


name: Unspecified Viral Hepatitis C with Hepatic Coma

description: Evidence of unspecified viral hepatitis C with hepatic coma.


name: Other Juvenile Arthritis, Unspecified Shoulder

description: Evidence of other juvenile arthritis in an unspecified shoulder not specified elsewhere.


name: Gastrointestinal Stromal Tumor Pathologic TNM Finding v8

description: A pathologic finding about one or more characteristics of gastrointestinal stromal tumor, following the rules of the TNM AJCC v8 classification system.


Less Than Partial Response in cGVHD

description: Change towards improvement from the pretreatment baseline, but not meeting the criteria for Complete Response or Partial Response in chronic Graft versus Host Disease (cGVHD).


name: Type 2 diabetes mellitus with diabetic dermatitis

description: Evidence of type 2 diabetes mellitus with diabetic dermatitis.


Stage IIB Esophageal Carcinoma

description: Stage IIB includes: For squamous cell carcinoma: (T2-3, N0, M0, G2-3, Tumor location: Upper, middle); (T1-2, N1, M0, Any G, Tumor location: Any).  For adenocarcinoma: (T3, N0, M0, Any G); (T1-2, N1, M0, Any G).  T2: Tumor invades muscularis propria. T3: Tumor invades adventitia. T1: Tumor invades lamina propria, muscularis mucosae, or submucosa.  N0: No regional lymph node metastasis.  N1: Metastasis in 1-2 regional lymph nodes.  M0: No distant metastasis.  G1: Well differentiated.  GX: Grade cannot be assessed-stage grouping as G1.  G2: Moderately differentiated.  G3: Poorly differentiated.  Tumor location: Location of the primary cancer site is defined by the position of the upper (proximal) edge of the tumor in the esophagus.  (AJCC 7th ed.)


name: Breast Cancer pT4a TNM Finding v6 and v7

description: Breast cancer with extension to the chest wall, not including the pectoralis muscle. (from AJCC 6th and 7th Eds.)


name: Grade 5 Right Ventricular Dysfunction, CTCAE

description: Death


name: manic episode with psychotic symptoms - severe

description: Evidence of manic episode, severe with psychotic symptoms.


PSA Level Ten to Fifteen

description: A blood concentration of prostate specific antigen between 10 ng/mL and 15 ng/mL.


Ovarian Rupture, CTCAE

description: A disorder characterized by tearing or disruption of the ovarian tissue.


Congenital spondylolysis

description: Spondylolysis, the cause of which is present from birth.


Grade 3 Folliculitis, CTCAE

description: >30% BSA; systemic intervention indicated


name: Acute Leukemia of Ambiguous Lineage, Not Otherwise Specified

description: Acute leukemia of ambiguous lineage, expressing combinations of markers that do not allow for its classification as either acute undifferentiated leukemia or mixed phenotype acute leukemia, and definitive classification along a single lineage is difficult. (WHO 2017)


name: Vascular Disorders - Other, Specify, CTCAE


Unresectable Esophageal Carcinoma

description: A carcinoma that arises from the esophagus and is not amenable to surgical resection.


Papillary mucinous cystadenocarcinoma

description: An invasive adenocarcinoma characterized by cystic changes, papillary growth pattern, and the presence of malignant glandular cells which contain intracytoplasmic mucin.


Prostate Cancer TNM Finding v6

description: A finding about one or more characteristics of prostate cancer, following the rules of the TNM AJCC v6 classification system.


name: Metastatic Primary Malignant Brain Neoplasm

description: A malignant neoplasm that arises from the brain and has spread from its original site of growth to other sites.


name: Orbital Sarcoma Clinical Distant Metastasis TNM Finding v8

description: A clinical finding about one or more characteristics of orbital sarcoma, following the rules of the TNM AJCC v8 classification system as they pertain to distant metastases.


Gastric Cancer pT1 TNM Finding v7

description: Gastric cancer invading lamina propria, muscularis mucosae, or submucosa. (from AJCC 7th Ed.)


Gastric Hepatoid Adenocarcinoma

description: A rare adenocarcinoma that arises from the gastric mucosa and is characterized by the presence of large polygonal malignant cells with eosinophilic cytoplasm resembling hepatocytes.


Anal squamous cell carcinoma metastatic

description: Anal squamous cell carcinoma that has spread from its primary site to another anatomic site.


name: Recurrent Endometrial Clear Cell Adenocarcinoma

description: The reemergence of endometrial clear cell adenocarcinoma after a period of remission.


Bone Sarcoma by AJCC v7 Stage

description: A term that refers to the staging of bone sarcoma, following the rules of the TNM AJCC v7 classification system.


name: Adrenal Cortical Carcinoma pN1 TNM Finding v8

description: Metastasis in regional lymph node(s). (from AJCC 8th Ed.)


name: Gastric Neuroendocrine Tumor cM1c TNM Finding v8

description: Gastric neuroendocrine tumor with both hepatic and extrahepatic metastases. (from AJCC 8th Ed.)


Cervical Cancer pT3a TNM Finding v9

description: Cervical cancer involving the lower third of vagina but not extending to pelvic wall. (from AJCC 9th Ed.)


CTRP Clinical Finding

description: A finding concept that has been requested by CTRP to be used in the disease field for abstraction and search of clinical trials.


name: Nasopharyngeal Cancer pTX TNM Finding v8

description: Nasopharyngeal cancer in which the primary tumor cannot be assessed. (from AJCC 8th Ed.)


Pulmonary Hypertension, CTCAE

description: A disorder characterized by an increase in pressure within the pulmonary circulation due to lung or heart disorder.


Cytogenetic Minimal Response

description: A minimal decrease in abnormal karyotype, based on pre-defined thresholds.


name: Recurrent Large Cell Neuroendocrine Carcinoma

description: The reemergence of large cell neuroendocrine carcinoma after a period of remission.


name: Kidney Infection with Unknown Absolute Neutrophil Count, CTCAE


name: Sedative, Hypnotic or Anxiolytic Dependence, Uncomplicated

description: Evidence of sedative, hypnotic or anxiolytic dependence, uncomplicated.


Hydrocephalus, CTCAE

description: A disorder characterized by an abnormal increase of cerebrospinal fluid in the ventricles of the brain.


Diffuse neurofibroma

description: A rare neurofibroma with an infiltrative growth pattern.  It involves the skin and subcutaneous tissue and grows in a plaque-like fashion.  Malignant transformation is rare.


Gastric Carcinoma with Lymphoid Stroma

description: A rare adenocarcinoma that arises from the gastric mucosa and is characterized by the presence of prominent lymphocytic stromal infiltration and poorly formed tubular structures.


Grade 2 Prostatic Hemorrhage, CTCAE

description: Moderate symptoms; intervention indicated


name: Breast Cancer pTis (Paget) TNM Finding v8

description: Paget disease of the nipple not associated with invasive carcinoma and/or carcinoma in situ (DCIS) in the underlying breast parenchyma. Carcinomas in the breast parenchyma associated with Paget disease are categorized based on the size and characteristics of the parenchymal disease, although the presence of Paget disease should still be noted. (from AJCC 8th Ed.)


PSA Level Less than Forty

description: A blood concentration of prostate specific antigen less than 40 ng/mL.


name: Myelodysplastic/Myeloproliferative Neoplasm, Not Otherwise Specified

description: A myelodysplastic/myeloproliferative neoplasm that does not meet the criteria of other myelodysplastic/myeloproliferative neoplasms, myelodysplastic syndromes, and myeloproliferative neoplasms. It is associated with cytopenia, blasts less than 20% in bone marrow and peripheral blood, thrombocytosis, and absence of genetic abnormalities associated with myeloid/lymphoid neoplasms with eosinophilia and tyrosine kinase gene fusions.


name: Cerebral Infarction due to Embolism of Unspecified Posterior Cerebral Artery

description: Evidence of cerebral infarction due to an embolism of an unspecified posterior cerebral artery.


Naevus spider acquired

description: A non-congenital, benign vascular lesion with a central punctum (arteriole) that is surrounded by thin-walled capillaries in a radial pattern. It occurs as the result of the dilatation of pre-existing vessels and is most often an incidental finding. The lesion may also be found in association with hypermetabolic states or chronic disease.


name: Metastatic Malignant Neoplasm in the Pelvic Cavity

description: The spread of a malignant neoplasm from a primary site to the pelvic cavity.


Hypertension, CTCAE

description: A disorder characterized by a pathological increase in blood pressure.


Grade 4 Papilledema, CTCAE

description: Best corrected visual acuity of 20/200 or worse in the affected eye


Antimicrobial Nonsusceptibility Result

description: A microbial susceptibility test result in which the growth of microorganisms is not inhibited by the usually achievable concentrations of antimicrobial agent when the recommended dosage is used for the site of infection. This category may be applied to new antimicrobial agents for which no resistant microorganisms have been encountered at the time the initial interpretive criteria are determined. Microorganisms that test with an MIC above or a zone measurement below the susceptible interpretive criteria may be designated as nonsusceptible. A designation of nonsusceptible does not necessarily mean that a resistance mechanism(s) exists in the microorganism.


name: Childhood Acute Lymphoblastic Leukemia CNS-Negative Toronto Guidelines v2

description: No clinical signs of CNS involvement and no blasts in CSF. (Childhood cancer staging for population registries according to the Toronto Childhood Cancer Stage Guidelines - Version 2. Cancer Council Queensland and Cancer Australia: Brisbane, Australia; 2021.)


name: Refractory Acute Undifferentiated Leukemia

description: Acute undifferentiated leukemia that does not respond to treatment.


Stage IV Urethral Cancer AJCC v8

description: Stage IV includes: (T4, N0, M0); (T4, N1, M0); (Any T, N2, M0); (Any T, Any N, M1). T4: For male penile urethra and female urethra: Tumor invades other adjacent organs (e.g., invasion of the bladder wall). For prostatic urethra: Tumor invades other adjacent organs (e.g., extraprostatic invasion of the bladder wall, rectal wall). N0: No regional lymph node metastasis. N1: Single regional lymph node metastasis in the inguinal region or true pelvis [perivesical, obturator, internal (hypogastric) and external iliac], or presacral lymph node. N2: Multiple regional lymph node metastasis in the inguinal region or true pelvis [perivesical, obturator, internal (hypogastric) and external iliac], or presacral lymph node. M0: No distant metastasis. M1: Distant metastasis. (AJCC 8th ed.)


Global DNA Hypomethylation

description: A genetic finding indicating decreased DNA methylation (in the form of decreased amounts of 5-methylcytosine) in CpG islands and promoter regions across the genome in an individual subject.


name: Grade 4 Artery Infection with Unknown Absolute Neutrophil Count, CTCAE


Grade 3 Movements Involuntary, CTCAE

description: Severe symptoms; limiting self care ADL


Parainfluenza Virus Infections

description: A viral infection caused by a parainfluenza virus, typically resulting in infections of the lower respiratory tract.


Grade 2 Duodenal Fistula, CTCAE

description: Symptomatic, invasive intervention not indicated


name: Skin disorder arising from mental factors

description: A skin disorder for which mental factors play a causative role.


Supraglottic Cancer pT4a TNM Finding v8

description: Supraglottic cancer with moderately advanced local disease. Tumor invades through the outer cortex of the thyroid cartilage and/or invades tissues beyond the larynx (e.g., trachea, soft tissues of neck including deep extrinsic muscle of the tongue, strap muscles, thyroid, or esophagus). (from AJCC 8th Ed.)


Aleukemic myeloid leukemia

description: Myeloid leukemia presenting with leukemic infiltration of tissues and normal or decreased leukocyte count in the peripheral blood.


Virus-Related Carcinoma

description: Carcinoma that develops in the context of an individual infected with a virus.


Vulvar Melanocytic Nevus

description: A benign, atypical, or dysplastic melanocytic nevus that arises from the vulva.


Enterotoxigenic E coli Infection

description: A pathotype of Escherichia coli, which is a gram-negative bacteria that is transmitted through the fecal-oral route. It has an incubation period of 10-72 hours and a duration of 1-5 days. Symptoms may include acute, occasionally severe diarrhea without fever.


name: Testicular Cancer Pathologic Regional Lymph Nodes TNM Finding v7

description: A pathologic finding about one or more characteristics of testicular cancer, following the rules of the TNM AJCC v7 classification system as they pertain to staging of regional lymph nodes.  (from AJCC 7th Ed.)


name: Soft Tissue Sarcoma of the Abdomen and Thoracic Visceral Organs Pathologic Regional Lymph Nodes TNM Finding v8

description: A pathologic finding about one or more characteristics of soft tissue sarcoma of the abdomen and thoracic visceral organs, following the rules of the TNM AJCC v8 classification system as they pertain to staging of regional lymph nodes.


Skin Lesion 15-200 mm

description: A skin lesion that measures between 15 and 200 mm in greatest dimension.


Personality unstable

description: Lability of an individual's outward presentation, which is characterized by unpredictable social behavior or uneven mood.


Rheumatoid Nodule, Left Hip

description: Evidence of rheumatoid nodule in the left hip.


name: Intestinal Metaplasia of Bladder Urachal Epithelium


Lung Cancer pTis TNM Finding v6 and v7

description: Lung cancer with a finding of carcinoma in situ. (from AJCC 6th and 7th Eds.)


name: Small Intestine Cancer Clinical Distant Metastasis TNM Finding v8

description: A clinical finding about one or more characteristics of small intestine cancer, following the rules of the TNM AJCC v8 classification system as they pertain to distant metastases.


Radiculitis, CTCAE

description: A disorder characterized by inflammation involving a nerve root. Patients experience marked discomfort radiating along a nerve path because of spinal pressure on the connecting nerve root.


Accidental Grass Fire Smoke Exposure

description: Environmental or occupational exposure to airborne gases and particulates produced during a grass fire that was not caused by deliberate human actions.


name: Grade 5 Neuroendocrine Prolactin Hormone Secretion Abnormality, CTCAE


name: Other Specified Rheumatoid Arthritis, Left Wrist

description: Evidence of other specified rheumatoid arthritis in the left wrist not specified elsewhere.


Grade 3 Accessory Nerve Disorder, CTCAE

description: Severe symptoms; limiting self care ADL


Grade 1 Proctitis, CTCAE

description: Rectal discomfort, intervention not indicated


Grade 2 Pelvic Pain, CTCAE

description: Moderate pain; limiting instrumental ADL


Bone Marrow Response

description: The response of the bone marrow to the treatment.


name: Exocrine Pancreatic Cancer pTX TNM Finding v8

description: Exocrine pancreatic cancer in which the primary tumor cannot be assessed. (from AJCC 8th Ed.)


name: Complete Atrioventricular Canal Defect Balanced

description: Atrioventricular septal defect in which the atrioventricular junction is shared evenly between the left ventricle and right ventricle.


name: Grade 1 Other Metabolic and Laboratory, CTCAE


Benign Liver Non-Epithelial Neoplasm

description: A non-epithelial neoplasm that arises from the liver and is characterized by the absence of atypical or malignant cytological and architectural features, and absence of invasive features or metastatic potential. Representative examples include hemangioma, angiomyolipoma, and solitary fibrous tumor.


name: Lip and Oral Cavity Cancer pN2a TNM Finding v8

description: Lip and oral cavity cancer with metastasis in a single ipsilateral lymph node, 3 cm or smaller in greatest dimension and ENE(+); or a single ipsilateral node larger than 3 cm but not larger than 6 cm in greatest dimension and ENE (-). (from AJCC 8th Ed.)


Cognitive Disturbance, CTCAE 5.0

description: A disorder characterized by a conspicuous change in cognitive function.


Gastrointestinal Stoma Necrosis, CTCAE

description: A disorder characterized by a necrotic process occurring in the gastrointestinal tract stoma.


Endometrioid intraepithelial neoplasia

description: A neoplastic clonal expansion of endometrial glands characterized by cytologic changes of the epithelium and the presence of an increased number of endometrial glands. The glands form crowded aggregates with tubular or branching patterns which are cytologically distinct from the background architectural and cytological pattern. It is associated with molecular changes seen in endometrioid endometrial carcinoma, including microsatellite instability, PAX2 inactivation, and PTEN, KRAS, and CTNNB1 gene mutations.


iRECIST Stable Disease

description: Cancer that is neither decreasing nor increasing in extent or severity based on predetermined boundaries following an initial apparent radiographic progression.


High Leukocyte Count

description: A higher than average level of leukocytes in a sample.


name: Ocular Adnexal Lymphoma pTX TNM Finding v7

description: Lymphoma extent is not specified. (from AJCC 7th Ed.)


name: AIDS-Related Malignant Cervical Neoplasm

description: A malignant neoplasm that arises from the cervix in a patient with acquired immunodeficiency syndrome. This category includes cervical carcinoma, Kaposi sarcoma, and non-Hodgkin lymphoma.


Pericarditis secondary to uremia

description: Inflammation of the pericardium associated with chronic kidney failure.


name: Cutaneous T-Cell Lymphoma, Unspecified, Intra-abdominal Lymph Nodes

description: Evidence of unspecified cutaneous T-cell lymphoma in the intra-abdominal lymph nodes.


Response in Target Lesion

description: A qualitative or quantitative measurement of the response of a target lesion(s) to the therapy.


name: Grade 1 Nasopharynx Intra-Operative Injury, CTCAE


Third Relapse

description: The reemergence of a disorder as diagnosed by clinical and/or laboratory evidence following three documented periods of remission.


Refractory Chronic Leukemia

description: Chronic leukemia that is resistant to treatment.


Grade 4 Endocarditis Infective, CTCAE

description: Life-threatening consequences; urgent intervention indicated


Lung Cancer pNX TNM Finding v8

description: Lung cancer in which the regional lymph nodes cannot be assessed.  (from AJCC 8th Ed.)


name: Adverse Event Associated with Constitutional Symptoms


Testicular cancer metastatic

description: A malignant germ cell tumor that arises from the testis and has spread to another anatomic site.


name: Postneoadjuvant Therapy Pathologic TNM Finding

description: Pathologic TNM staging performed with access to postneoadjuvant therapy information only.


name: Non-Functioning Pancreatic Neuroendocrine Tumor G1

description: A low grade well differentiated neoplasm with neuroendocrine differentiation that arises from the pancreas. It is characterized by the absence of a hormone-related clinical syndrome.


name: Grade 3 Carbon Monoxide Diffusion Capacity, CTCAE


description: Evidence of alcohol abuse with alcohol-induced psychotic disorder with delusions.


name: Other Paralytic Syndrome following Non-Traumatic Subarachnoid Hemorrhage Affecting Right Non-Dominant Side

description: Evidence of other paralytic syndrome following non-traumatic subarachnoid hemorrhage affecting right non-dominant side not specified elsewhere.


Urostomy Leak, CTCAE

description: A finding of leakage of contents from a urostomy.


name: Childhood Connective and Soft Tissue Neoplasm

description: A soft tissue or bone neoplasm that occurs during childhood.


name: Female Reproductive System Cancer TNM Finding v9

description: A finding about one or more characteristics of female reproductive system cancer, following the rules of the TNM AJCC v9 classification system. The AJCC v9 changes align with the International Federation of Gynecology and Obstetrics (FIGO) staging.


name: Supraglottic Cancer Pathologic Distant Metastasis TNM Finding v7

description: A pathologic finding about one or more characteristics of supraglottic cancer, following the rules of the TNM AJCC v7 classification system as they pertain to distant metastases.  There is no pathologic M0 for supraglottic cancer.


name: Arterial Thrombosis Related to Vascular Access Complication

description: The formation of a thrombus in the artery as a direct result of an activity associated with vascular access.


name: Lugano Classification Stage I Hodgkin Lymphoma AJCC v8

description: Stage I: Involvement of a single lymphatic site (i.e., nodal region, Waldeyer's ring, thymus, or spleen). (from AJCC 8th Ed.)


name: Malignant Osteoclastic Giant Cell-Rich Tumor of Bone

description: A giant cell tumor that arises from the bone and is characterized by the presence of a malignant cellular component.


Neonatal Hypotension, AE

description: An adverse event in a newborn characterized by abnormally low blood pressure, which is usually symptomatic.


name: Refractory Sclerodermatous Graft Versus Host Disease

description: Sclerodermatous Graft Versus Host Disease that is resistant to treatment.


name: Bladder Cancer pT3 TNM Finding v6 and v7

description: Bladder cancer with tumor invading the perivesical tissue. (from AJCC 6th and 7th Eds.)


name: Grade 4 Cranial Nerve VII Sensory Intra-Operative Injury, CTCAE


Grade 1 Photophobia, CTCAE

description: Symptomatic but not limiting ADL


Infectious Encephalomyelitis

description: An infectious process that affects the brain and spinal cord tissues. It is usually caused by viruses.


Acral nevus

description: A melanocytic nevus that arises from the palms, soles, and nails.


name: Early T Precursor Acute Lymphoblastic Leukemia with BCL11B Rearrangement

description: An early T precursor acute lymphoblastic leukemia associated with the presence of BCL11B gene rearrangement.


name: Mucosal Melanoma of the Head and Neck pT3 TNM Finding v8

description: Mucosal melanoma of the head and neck with tumor limited to the mucosa and immediately underlying soft tissue, regardless of thickness or greatest dimension; for example, polypoid nasal disease, pigmented or nonpigmented lesions of the oral cavity, pharynx, or larynx. (from AJCC 8th Ed.)


Grade 1 Vaginal Hemorrhage, CTCAE

description: Mild symptoms; intervention not indicated


name: Arthropathy following Intestinal Bypass, Left Ankle and Foot

description: Evidence of arthropathy following intestinal bypass in the left ankle and foot.


Grade 5 Arachnoiditis, CTCAE

description: Death


name: Grade 3 Rectum Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


Stage IIA2 Cervical Cancer AJCC v8

description: Stage IIA2 includes: T2a2, Any N, M0. T2a2: Cervical carcinoma invading beyond the uterus but not to the pelvic wall or to lower third of vagina without parametrial invasion. Clinically visible lesion more than 4.0 cm in greatest dimension. M0: No distant metastasis. (AJCC 8th Ed.)


name: Acute Myeloid Leukemia with STAG2 Mutation

description: An acute myeloid leukemia associated with STAG2 gene mutation.


name: Cranial Nerve X Intra-Operative Injury, CTCAE


Malignant Neoplasm of Left Ureter

description: Evidence of a malignant neoplasm of the left ureter.


Liver Germ Cell Tumor

description: A benign or malignant extragonadal germ cell tumor that arises from the liver. Representative examples include teratoma and yolk sac tumor.


Loss of INI 1 Protein Expression

description: An immunohistochemical finding indicating negative staining of tumor cells for INI 1 protein, resulting from the inactivation of the INI 1 tumor suppressor gene.


Grade 2 Dysesthesia, CTCAE

description: Moderate sensory alteration; limiting instrumental ADL


name: Malignant Neoplasm of Overlapping Sites of Unspecified Male Breast

description: Evidence of a malignant neoplasm of overlapping sites of unspecified male breast.


Grade 2 Bronchopulmonary Dysplasia, AE

description: An adverse event in a newborn characterized by the need for supplemental oxygen at 28 days AND need for 22-30% oxygen at 36 weeks postmenstrual age (PMA) in infants born less than 32 weeks' gestation; need for 22-30% oxygen by 56 days postnatal age in infants born greater than 32 weeks' gestation; need for 22-30% oxygen at discharge. Note: For conversion of oxygen administered by different modalities to fraction of inspired oxygen (FiO2): see http://nicutools.org/MediCalcs/ActualO2.php3.


name: Refractory Fallopian Tube Mucinous Adenocarcinoma

description: Fallopian tube mucinous adenocarcinoma that is resistant to treatment.


ITGAD Negative

description: An indication that ITGAD expression has not been detected in a sample.


Grade 3 Prolapse of Urostomy, CTCAE

description: Dysfunctional stoma; elective operative intervention or major stomal revision indicated


name: Borrelia Burgdoferi-Associated Primary Cutaneous Marginal Zone Lymphoproliferative Disorder

description: Primary cutaneous marginal zone lymphoproliferative disorder that arises from chronically stimulated lymphoid tissue in the skin in response to Borrelia burgdoferi infection.


name: Appendicular Skeleton, Trunk, Skull, and Facial Bones Cancer pT1 TNM Finding v8

description: Appendicular skeleton, trunk, skull, and facial bones cancer with tumor measuring 8 cm or less in greatest dimension. (from AJCC 8th Ed.)


name: Grade 4 Peritoneal Cavity Intra-Operative Injury, CTCAE


Grade 1 Neonatal Fever, AE

description: An adverse event in a newborn characterized by isolated, not sustained fever, no change in baseline age-appropriate behavior.


name: Grade 3 Breast Volume and Hypoplasia, CTCAE


Adolescent Gynecomastia

description: Gynecomastia that occurs during puberty and is not due to exogenous substances or disease processes.


malignant neoplasm of the left orbit

description: Evidence of a malignant neoplasm of the left orbit.


name: Rheumatoid Myopathy with Rheumatoid Arthritis of Right Knee

description: Evidence of rheumatoid myopathy with rheumatoid arthritis of right knee.


name: Anal Canal Cancer by AJCC v6 and v7 Stage

description: A term that refers to the staging of anal canal cancer according to the American Joint Committee on Cancer, 6th and 7th editions. This staging system applies to carcinomas arising in the anal canal only; melanomas, carcinoid tumors, sarcomas, and perianal tumors are not included. (from AJCC 6th and 7th Eds.)


Kidney Cancer pM0 TNM Finding

description: Kidney cancer with no distant metastasis. (from AJCC 6th Ed.)


name: Toxic Liver Disease with Hepatitis NEC in NCI Thesaurus

description: Evidence of toxic liver disease with hepatitis, not elsewhere classified.


Grade 5 Perforation Bile Duct, CTCAE

description: Death


name: Small Intestine Cancer pT1a TNM Finding v8

description: Small intestine cancer with tumor invading the lamina propria. (from AJCC 8th Ed.)


name: Chest Pain in Right Fifth Intercostal Space

description: The location of the chest pain is within the fifth intercostal space on the right side.


Metastatic Lesion

description: A tumor arising at a location distant to the primary lesion.


name: Unspecified Juvenile Rheumatoid Arthritis, Unspecified Shoulder

description: Evidence of unspecified juvenile rheumatoid arthritis in an unspecified shoulder.


Mural Nodule

description: A solid, sharply demarcated, benign or malignant nodular mass that is attached to the wall of an organ.


Renal lymphocele

description: Encapsulated collection of lymphatic fluid around a transplanted kidney.


name: Post-Dysenteric Arthropathy, Unspecified Site

description: Evidence of post-dysenteric arthropathy in an unspecified site.


Periorbital Infection, CTCAE

description: A disorder characterized by an infectious process involving the orbit of the eye.


name: Refractory T Acute Lymphoblastic Leukemia

description: T-acute lymphoblastic leukemia that does not respond to treatment.


name: Cutaneous Follicular Center Lymphoma, Lymph Nodes of Inguinal Region and Lower Limb

description: Evidence of cutaneous follicular center lymphoma in the lymph nodes of inguinal region and lower limb.


Metastatic Acral Lentiginous Melanoma

description: Acral lentiginous melanoma that has spread from its original site of growth to another anatomic site.


Unresectable Solid Neoplasm

description: A solid neoplasm that is not amenable to surgical resection.


name: Grade 2 Penis Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


Grade 5 Testicular Hemorrhage, CTCAE

description: Death


name: Male Penile Urethra and Female Urethra Cancer pT0 TNM Finding v8

description: Urethral cancer with no evidence of primary tumor. (from AJCC 8th Ed.)


Radiation burn

description: A burn caused by exposure to x-ray, radium, sunlight, atomic or any other type of radiant energy.


Grade 2 Skin Ulceration, CTCAE

description: Combined area of ulcers 1-2 cm; partial thickness skin loss involving skin or subcutaneous fat


name: Grade 3 Abdominal Distension or Bloating, CTCAE


name: Human Papillomavirus-Related Vaginal Adenocarcinoma

description: An adenocarcinoma that arises from the vagina and is caused by human papillomavirus infection.


name: Drug or Chemical Induced Diabetes Mellitus with Unspecified Diabetic Retinopathy with Macular Edema

description: Evidence of drug or chemical induced diabetes mellitus with unspecified diabetic retinopathy with macular edema.


name: Recurrent HIV-Related Lymphoproliferative Disorder

description: The reemergence of HIV-associated lymphoproliferative disorder after a period of remission.


name: Testicular Spermatocytic Tumor with Sarcoma

description: A malignant germ cell tumor that arises from the testis and is characterized by the presence of a spermatocytic tumor component that is contiguous with an undifferentiated or differentiated sarcomatous component.  It usually presents as a slowly growing mass that enlarges very rapidly soon after the initial diagnosis.


name: Conjunctival Melanoma cM0 TNM Finding v8

description: Conjunctival melanoma with no distant metastasis. (from AJCC 8th Ed.)


Myocardial Infarction, CTCAE

description: A disorder characterized by gross necrosis of the myocardium; this is due to an interruption of blood supply to the area.


Toxic Epidermal Necrolysis, CTCAE

description: A disorder characterized by greater than 30% total body skin area separation of dermis. The syndrome is thought to be a hypersensitivity complex affecting the skin and the mucous membranes.


name: Metastatic Gastric Neuroendocrine Carcinoma

description: A gastric neuroendocrine carcinoma that has spread from its original site of growth to another anatomic site.


Uveal Melanoma pN1a TNM Finding v8

description: Uveal melanoma with metastasis in one or more regional lymph node(s). (from AJCC 8th Ed.)


Other Lymphoid Leukemia, in Relapse

description: Evidence of other lymphoid leukemia in relapse not specified elsewhere.


name: Progesterone Receptor-Positive Malignant Neoplasm

description: A malignant neoplasm that is positive for progesterone receptors.


Rhinorrhea, CTCAE

description: A disorder characterized by excessive mucous secretions draining from the nose.


description: Myelofibrosis that develops in a patient with history of essential thrombocythemia.


name: Malignant Neoplasm of Left Acoustic Nerve

description: Evidence of a malignant neoplasm of the left acoustic nerve.


name: Merkel Cell Carcinoma of Right Upper Limb, Including Shoulder

description: Evidence of Merkel cell carcinoma of right upper limb including the shoulder.


Perinatal Exposure

description: Exposure to potentially harmful chemical, physical, or biological agents in utero or pre-conception.


name: Gallbladder Cancer Clinical TNM Finding v7

description: A clinical finding about one or more characteristics of gallbladder cancer, following the rules of the TNM AJCC v7 classification system.  The clinical evaluation usually depends on the results of ultrasonography, computed tomography, and magnetic resonance cholangiopancreatography.  Clinical staging may also be based on findings from surgical exploration (laparoscopic or open) when the main tumor mass is not resected.  (from AJCC 7th Ed.)


name: Locally Advanced Digestive System Carcinoma

description: Digestive system carcinoma that has spread to nearby tissues or lymph nodes.


Grade 1 Gastroparesis, CTCAE

description: Mild nausea, early satiety and bloating, able to maintain caloric intake on regular diet


Arterial Thromboembolism, CTCAE

description: A disorder characterized by occlusion of an arterial vessel by a blood clot that develops in an artery.


name: Grade 5 Anus Mucositis or Stomatitis by Functional or Symptomatic Classification, CTCAE


name: Ocular Adnexal Lymphoma pT3 TNM Finding v7

description: Lymphoma with preseptal eyelid involvement +/- orbital involvement +/- any conjunctival involvement.  Note: Preseptal tissues include dermis and orbicularis muscle of the anterior eyelid skin.  (from AJCC 7th Ed.)


name: Grade 3 Gallbladder Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


Vaginal Cancer pT2b TNM Finding v8

description: Vaginal cancer with tumor invading paravaginal tissues but not to pelvic wall, measuring more than 2.0 cm. (from AJCC 8th Ed.)


Grade 2 Bacteremia, CTCAE

description: Blood culture positive with no signs or symptoms


name: Grade 4 Fallopian Tube Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


CD15 Negative

description: An indication that CD15 antigen expression has not been detected in a sample.


name: Chronic Myeloid Leukemia, BCR-ABL Positive, not Having Achieved Remission

description: Evidence of chronic myeloid leukemia, BCR-ABL positive, not having achieved remission.


Metastatic Benign Neoplasm

description: A very rare benign neoplasm that metastasizes inexplicably. This category includes metastasizing pleomorphic adenoma of the salivary gland and uterine corpus metastasizing leiomyoma.


name: Other Stimulant Dependence with Stimulant-Induced Psychotic Disorder with Hallucinations

description: Evidence of other stimulant dependence with stimulant-induced psychotic disorder with hallucinations not specified elsewhere.


Grade 3 Urostomy Site Bleeding, CTCAE

description: Transfusion indicated; invasive intervention indicated


name: Refractory Low Grade Fallopian Tube Serous Adenocarcinoma

description: Low grade fallopian tube serous adenocarcinoma that is resistant to treatment.


name: Grade 4 Dental-Tooth Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


name: Refractory Malignant Urinary System Neoplasm

description: Malignant urinary system neoplasm that is resistant to treatment.


name: Grade 1 Superior Vena Cava Vein Injury, CTCAE


name: Grade 2 Retina Intra-Operative Injury, CTCAE


name: Nasal Cavity and Paranasal Sinus Cancer TNM Finding v6

description: A finding about one or more characteristics of nasal cavity and paranasal sinus cancer, following the rules of the TNM AJCC v6 classification system.


name: Grade 4 Biliary Tree NOS Intra-Operative Injury, CTCAE


Adenosarcoma pT2b TNM Finding v7

description: Tumor involves other pelvic tissues. (from AJCC 7th Ed.)


Grade 2 Hematoma, CTCAE

description: Minimally invasive evacuation or aspiration indicated


ESR2 Negative

description: An indication that expression of ESR2 has not been detected in a sample.


name: Nasal Cavity and Ethmoid Sinus Cancer Pathologic Regional Lymph Nodes TNM Finding v6

description: A pathologic finding about one or more characteristics of nasal cavity and ethmoid sinus cancer, following the rules of the TNM AJCC v6 classification system as they pertain to staging of regional lymph nodes.


name: Grade 5 Bronchus Infection with Unknown Absolute Neutrophil Count, CTCAE


name: Grade 1 Adrenal Gland Intra-Operative Injury, CTCAE


name: Merkel Cell Carcinoma pN1a TNM Finding v8

description: Merkel cell carcinoma with clinically occult regional lymph node metastasis following lymph node dissection. (from AJCC 8th Ed.)


Signet Ring Melanoma

description: A rare variant of cutaneous melanoma, characterized by the presence of malignant cells with signet-ring morphology.


Junctional melanocytic nevus of skin

description: A nevus characterized by the presence of an intraepidermal proliferation of nevus cells. The nevus cells form multiple nests in the dermal-epidermal junction. It presents as a small, slightly raised, pigmented skin lesion.


Mucosal lentiginous melanoma

description: An acral lentiginous melanoma affecting mucosal surfaces.


name: Grade 2 Foreign Body Infection with Unknown Absolute Neutrophil Count, CTCAE


name: Thyroid Cancer Pathologic TNM Finding v6

description: A pathologic finding about one or more characteristics of thyroid cancer, following the rules of the TNM AJCC v6 classification system. TNM pathologic findings are based on clinical findings supplemented by histopathologic examination of one or more tissue specimens acquired during surgery.


name: Grade 2 Dental-Tooth Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


name: Chemically Induced Irreversible Toxicity


Malignant Neoplasm of Left Epididymis

description: Evidence of a malignant neoplasm of the left epididymis.


name: Grade 5 Peristomal Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


name: Grade 5 Stomach Mucositis or Stomatitis by Clinical Examination Classification, CTCAE


Other Persistent Mood Disorders

description: Evidence of other persistent mood disorders not specified elsewhere.


name: Grade 3 Kidney Infection with Unknown Absolute Neutrophil Count, CTCAE


name: Rheumatoid Arthritis with Rheumatoid Factor of Multiple Sites without Organ or Systems Involvement

description: Evidence of rheumatoid arthritis with rheumatoid factor of multiple sites without organ or systems involvement.


Testicular Cancer cN0 TNM Finding v8

description: Testicular cancer with no regional lymph node metastasis. (from AJCC 8th Ed.)


Lung Cancer pTis TNM Finding v8

description: Lung cancer with a finding of carcinoma in situ. Squamous cell carcinoma in situ (SCIS). Adenocarcinoma in situ (AIS): adenocarcinoma with pure lepidic pattern, 3 cm or less in greatest dimension. (from AJCC 8th Ed.)


Childhood Junctional Nevus

description: A junctional nevus that occurs during childhood.


Metastatic Visceral Disease

description: Metastases to the viscera, predominantly involving the lung and liver, that present with subjective evidence of disease as perceived by the patient.


Hypoxic-Ischemic Encephalopathy

description: Ischemic brain damage in which the entire brain is deprived of oxygen. It may be fatal or lead to long term disabilities including developmental delays, intellectual disability, and seizures.


name: Merkel Cell Carcinoma pT1 TNM Finding v7

description: Merkel cell carcinoma with less than or equal to 2 cm maximum tumor dimension. (from AJCC 7th Ed.)


Adult Grade III Meningioma

description: A grade III meningioma that occurs during adulthood.


Grade 4 Infective Myositis, CTCAE

description: Life-threatening consequences; urgent intervention indicated


Indeterminate Lymph-Vascular Invasion

description: A response that the lymphatic invasion of a specimen is indeterminate.


name: Colon Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


Grade I Meningioma

description: A benign meningioma which may recur in approximately 7-20% of the cases.  This category includes the angiomatous meningioma, fibrous meningioma, lymphoplasmacyte-rich meningioma, meningothelial meningioma, metaplastic meningioma, microcystic meningioma, psammomatous meningioma, secretory meningioma, and transitional meningioma.


Stage II Vulvar Cancer AJCC v8

description: Stage II includes: T2, N0, M0. T2: Tumor of any size with extension to adjacent perineal structures (lower/distal third of the urethra, lower/distal third of the vagina, anal involvement). N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 8th Ed.)


name: Grade 5 Ureter Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


Grade 4 Watering Eyes, CTCAE

description: Best corrected visual acuity of 20/200 or worse in the affected eye


Recurrent Laryngeal Nerve Paralysis

description: Paralysis of the recurrent laryngeal nerve. Causes include surgical and non-surgical traumas, neoplasms (e.g., lung carcinoma), and inflammatory neuritis.


name: Grade 2 Lip or Perioral Infection with Unknown Absolute Neutrophil Count, CTCAE


Grade 2 Tracheal Stenosis, CTCAE

description: Symptomatic (e.g., noisy airway breathing), no respiratory distress; medical intervention indicated (e.g., steroids); limiting instrumental ADL


Iris Melanoma pT1 TNM Finding v8

description: Iris melanoma with tumor limited to the iris. (from AJCC 8th Ed.)


ESR1 Gene Mutation Negative

description: A genetic finding indicating that ESR1 gene mutations have not been detected in a sample.


name: Recurrent Central Nervous System Lymphoma

description: The reemergence of central nervous system lymphoma after a period of remission.


name: Grade 2 Jejunum Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


name: Grade 3 Heart Intra-Operative Injury, CTCAE


Esophageal Ulcer, CTCAE

description: A disorder characterized by a circumscribed, erosive lesion on the mucosal surface of the esophageal wall.


name: Male Penile Urethra and Female Urethra Cancer pTis TNM Finding v8

description: Urethral cancer with a finding of carcinoma in situ. (from AJCC 8th Ed.)


name: Non-Traumatic Subarachnoid Hemorrhage from Unspecified Intracranial Artery

description: Evidence of non-traumatic subarachnoid hemorrhage from unspecified intracranial artery.


name: Atherosclerosis of Autologous Vein Bypass Graft(s) of Left Leg with Ulceration of Other Part of Lower Leg

description: Evidence of atherosclerosis of autologous vein bypass graft(s) of left leg with ulceration of other part of lower leg.


Grade 3 INR Increased, CTCAE

description: >2.5; >2.5 x baseline if on anticoagulation; bleeding


Kidney Paraganglioma

description: An extremely rare paraganglioma that arises from the renal hilum. Paragangliomas that arise from the perihilar sympathetic ganglia are not included in this category.


name: Anaplastic Large Cell Lymphoma, ALK-Positive, Lymph Nodes of Head, Face, and Neck

description: Evidence of anaplastic large cell lymphoma that is ALK-Positive in the lymph nodes of head in the face in the and neck.


Laryngeal Cancer cN3a TNM Finding v8

description: Laryngeal cancer with metastasis in a lymph node, more than 6 cm in greatest dimension and ENE(-). (from AJCC 8th Ed.)


name: Unspecified Juvenile Rheumatoid Arthritis, Left Hip

description: Evidence of unspecified juvenile rheumatoid arthritis in the left hip.


name: Atherosclerosis of Autologous Vein Bypass Graft(s) of the Extremities with Intermittent Claudication, Right Leg

description: Evidence of atherosclerosis of autologous vein bypass graft(s) of the extremities with intermittent claudication in the right leg.


Bladder Cancer pM1b TNM Finding v8

description: Bladder cancer with non-lymph node distant metastases. (from AJCC 8th Ed.)


name: Digestive System Neuroendocrine Tumor G2

description: A well differentiated, intermediate grade neoplasm with neuroendocrine differentiation that arises from the digestive system. The mitotic count is 2-20 per 10 HPF and/or the Ki67 index is 3 to 20 percent.


name: High Grade Prostatic Intraepithelial Neoplasia, Mucinous Variant

description: High grade prostatic intraepithelial neoplasia characterized by the presence of masses of mucin within the affected distended glands.


name: Malignant neoplasm of peripheral nerves of trunk, unspecified

description: Evidence of a malignant neoplasm of the peripheral nerves of trunk.


name: Grade 1 Otitis External Ear Non Infectious, CTCAE


name: Stage M0 Childhood Ependymoma by Toronto Guidelines v2

description: No visible disease on imaging (MRI brain and spine) beyond primary site of disease and no tumor cells in the CSF. (Childhood cancer staging for population registries according to the Toronto Childhood Cancer Stage Guidelines - Version 2. Cancer Council Queensland and Cancer Australia: Brisbane, Australia; 2021.)


name: Rheumatoid Myopathy with Rheumatoid Arthritis of Left Elbow

description: Evidence of rheumatoid myopathy with rheumatoid arthritis of left elbow.


name: Grade 2 Lower Extremity Artery Injury, CTCAE


Malignant neoplasm of stomach recurrent

description: The reemergence of a malignant neoplasm of the stomach after a period of remission.


pN2a TNM Finding

description: A pathologic regional lymph node TNM finding. The definition of pN2a finding depends on the particular type of cancer that it refers to; for example, for breast cancer, pN2a finding is defined as follows: cancer with metastasis in 4-9 axillary lymph nodes (at least one tumor deposit larger than 2.0 mm). (from AJCC 8th Ed.)


Stage I Cervical Cancer AJCC v8

description: Stage I includes: T1, Any N, M0. T1: Tumor confined to uterus (extension to corpus should be disregarded). M0: No distant metastasis. (AJCC 8th Ed.)


name: Atherosclerosis of Non-Autologous Biological Bypass Graft(s) of the Extremities with Gangrene, Bilateral Legs

description: Evidence of atherosclerosis of non-autologous biological bypass graft(s) of the extremities with gangrene in both legs.


name: Fallopian Tube Cancer pT2b TNM Finding v7

description: Fallopian tube cancer with extension to other pelvic structures. (from AJCC 7th Ed.)


Blastic Granulocytic Sarcoma

description: A granulocytic sarcoma composed primarily of myeloblasts (WHO 2001).


Childhood NUT Carcinoma

description: A NUT carcinoma that occurs during childhood.


name: Lobular Endocervical Glandular Hyperplasia

description: Lobular proliferations of benign-appearing small to moderate sized endocervical glands in the inner half of the cervical stroma. The glands are lined by columnar epithelial cells which contain pyloric gland-type mucin. There is minimal atypia and mitotic figures are rare. Some cases have been associated with adenocarcinoma in situ/high grade cervical glandular intraepithelial neoplasia and gastric-type adenocarcinomas.


name: Grade 4 Duodenum Intra-Operative Injury, CTCAE


name: Urothelial (Transitional Cell) Carcinoma of the Prostate Pathologic Primary Tumor TNM Finding v7

description: A pathologic finding about one or more characteristics of urothelial (transitional cell) carcinoma of the prostate, following the rules of the TNM AJCC v7 classification system as they pertain to staging of the primary tumor.


Paratesticular Serous Cystadenoma

description: A rare serous cystadenoma that arises from the paratesticular structures.


name: Grade 3 Genitourinary Stoma Prolapse, CTCAE


name: Follicular Lymphoma, Unspecified, Intrathoracic Lymph Nodes

description: Evidence of unspecified follicular lymphoma in the intrathoracic lymph nodes.


name: Malignant Neoplasm of Connective and Soft Tissue of Left Upper Limb, Including Shoulder

description: Evidence of a malignant neoplasm of connective and soft tissue of left upper limb including the shoulder.


Grade 1 Toothache, CTCAE

description: Mild pain


Pocket erosion

description: Erosion of patient's skin pocket which houses a device.


name: Grade 3 Stenosis of Gastrointestinal Stoma, CTCAE

description: Severely altered GI function; tube feeding, TPN or hospitalization indicated; elective operative intervention indicated


name: Other Paralytic Syndrome following Other Non-Traumatic Intracranial Hemorrhage Affecting Right Non-Dominant Side

description: Evidence of other paralytic syndrome following other non-traumatic intracranial hemorrhage affecting right non-dominant side not specified elsewhere.


name: Other atherosclerosis of unspecified type of bypass graft(s) of the extremities, bilateral legs

description: Evidence of other atherosclerosis of unspecified type of bypass graft(s) of the extremities in both legs not specified elsewhere.


Grade 1 Ovarian Hemorrhage, CTCAE

description: Mild symptoms; intervention not indicated


name: Neoplasm of Uncertain Behavior of Brain, Unspecified

description: Evidence of neoplasm of uncertain behavior of brain.


name: Clonal Cytopenia with Monocytosis of Undetermined Significance

description: A myelodysplastic/myeloproliferative neoplasm that fulfills the diagnostic criteria of clonal monocytosis of undetermined significance and is associated with cytopenia.


Thyroid Cancer pN1b TNM Finding v7

description: Thyroid cancer with metastasis to unilateral, bilateral or contralateral cervical (Levels I, II, III, IV, or V) or retropharyngeal or superior mediastinal lymph nodes (Level VII). (from AJCC 7th Ed.)


Other Rheumatic Mitral Valve Diseases

description: Evidence of other rheumatic mitral valve diseases not specified elsewhere.


Ventricular Tachycardia, CTCAE 5.0

description: A disorder characterized by a dysrhythmia with a heart rate greater than 100 beats per minute that originates distal to the bundle of His.


name: Grade 1 Scleral Necrosis and Melt, CTCAE


Stage II Pancreatic Cancer AJCC v8

description: Stage II includes: IIA: (T3, N0, M0); IIB: (T1, N1, M0); (T2, N1, M0); (T3, N1, M0). T1: Tumor measuring 2 cm or less in greatest dimension. T2: Tumor measuring more than 2 cm and 4 cm or less in greatest dimension. T3: Tumor measuring more than 4 cm in greatest dimension. N0: No regional lymph node metastasis. N1: Metastasis in one to three regional lymph nodes. M0: No distant metastasis. (AJCC 8th ed.)


Urethral Cancer pTX TNM Finding v7

description: Urethral cancer in which the primary tumor cannot be assessed. (from AJCC 7th Ed.)


Pituitary hemorrhage

description: Bleeding within the pituitary gland.


Radiation-Related Osteosarcoma

description: A high grade osteosarcoma arising in an irradiated bone.


name: Abnormal Cardiac Event Monitoring Finding

description: A history of having had an abnormal finding during cardiac event monitoring.


recurrent adult acute myeloid leukemia

description: The reemergence of acute myeloid leukemia in adults after a period of remission.


name: No Specific Molecular Profile Endometrial Endometrioid Adenocarcinoma

description: An endometrial endometrioid adenocarcinoma characterized by the absence of POLE gene mutations, mismatch repair (MMR) deficiency, and p53 gene mutations.


name: Jejunum and Ileum Neuroendocrine Tumor Clinical Distant Metastasis TNM Finding v8

description: A clinical finding about one or more characteristics of a jejunum and ileum neuroendocrine tumor, following the rules of the TNM AJCC v8 classification system as they pertain to distant metastases.


Bladder Cancer pM1 TNM Finding v8

description: Bladder cancer with distant metastasis. (from AJCC 8th Ed.)


Pancreatic Intraductal Neoplasms

description: A group of cystic or mass-forming epithelial neoplasms that arise from the exocrine pancreas, exhibit ductal differentiation, and grow mostly within the pancreatic ducts.  This group includes the pancreatic intraductal papillary mucinous neoplasms and the pancreatic intraductal tubulopapillary neoplasms.


name: No Evidence of Hormonal Immunoreactivity Present


name: Vaginal Cancer Pathologic Primary Tumor TNM Finding v7

description: A pathologic finding about one or more characteristics of vaginal cancer, following the rules of the TNM AJCC v7 classification system as they pertain to staging of the primary tumor.


name: Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma, Unspecified, Extranodal and Solid Organ Sites

description: Evidence of an unspecified mature T-cell and NK-cell non-Hodgkin lymphoma in the extranodal and solid organ sites.


name: Oral Cavity or Gum Infection with Unknown Absolute Neutrophil Count, CTCAE


Great vessel abnormalities

description: A congenital vascular abnormality that affects the great vessels and/or aortic arch. Representative examples include double aortic arch, aortic coarctation, and absence of a pulmonary artery.


Life Threatening Illness or Injury

description: Patient suffered an illness or injury which if not treated would be fatal.


Cervical Cancer pM1 TNM Finding v9

description: Cervical cancer with microscopic confirmation of distant metastasis including inguinal lymph nodes, lung, liver, bone, or intraperitoneal metastases. Metastases to pelvic or paraaortic lymph nodes, or vagina are excluded. (from AJCC 9th Ed.)


Monoplegia of upper limb

description: Evidence of monoplegia of upper limb affecting unspecified side.


Embolism and thrombosis of iliac artery

description: Evidence of embolism and thrombosis of iliac artery.


name: Granulomatous Hepatitis, not Elsewhere Classified in NCI Thesaurus

description: Evidence of granulomatous hepatitis, not elsewhere classified.


name: Grade 1 Neutrophil Count Decreased, CTCAE

description: <LLN-1500/mm3; <LLN-1.5 x 10e9/L


Stage I Appendix Carcinoma AJCC v7

description: Stage I includes: (T1, N0, M0); (T2, N0, M0). T1: Tumor invades submucosa.  T2: Tumor invades muscularis propria. N0: No regional lymph node metastasis.  M0: No distant metastasis. (AJCC 7th ed.)


Radiation-Induced Vascular Disease

description: A vascular disease caused by radiation.


name: Colorectal Cancer Clinical TNM Finding v7

description: A clinical finding about one or more characteristics of colorectal cancer, following the rules of the TNM AJCC v7 classification system.  Clinical assessment is based on medical history, physical examination, sigmoidoscopy, and colonoscopy with biopsy.  Examinations designed to demonstrate the presence of extrarectal or extracolonic metastasis may include chest radiographic films, computed tomography (CT; abdomen, pelvis, chest), magnetic resonance imaging (MRI), and positron emission tomography (PET) or fused PET/CT scans. (from AJCC 7th Ed.)


Grade 3 Colonic Ulcer, CTCAE

description: Severely altered GI function; TPN indicated; elective invasive intervention indicated


name: Other Stimulant Dependence with Intoxication with Perceptual Disturbance

description: Evidence of other stimulant dependence with intoxication with perceptual disturbance not specified elsewhere.


MLH1 Negative

description: An indication that expression of MLH1 has not been detected in a sample.


Cytogenetic Partial Response

description: A partial decrease in abnormal karyotype, based on pre-defined thresholds.


name: Post-Immunization Arthropathy, Right Ankle and Foot

description: Evidence of post-immunization arthropathy in the right ankle and foot.


name: Pleural Malignant Mesothelioma Pathologic Regional Lymph Nodes TNM Finding v8

description: A pathologic finding about one or more characteristics of pleural malignant mesothelioma, following the rules of the TNM AJCC v8 classification system as they pertain to staging of regional lymph nodes.


name: Metastatic Sarcomatoid Urothelial Carcinoma

description: Sarcomatoid urothelial carcinoma that has spread to another anatomical site.


name: Hypertensive Chronic Kidney Disease with Stage 5 Chronic Kidney Disease or End Stage Renal Disease

description: Evidence of hypertensive chronic kidney disease with stage 5 chronic kidney disease or end stage renal disease.


name: Grade 3 Large Bowel Mucositis or Stomatitis by Functional or Symptomatic Classification, CTCAE


name: Grade 4 Ejection Fraction Decreased, CTCAE

description: Resting ejection fraction (EF) <20%


Second degree perineal laceration

description: Injury to perineum involving perineal muscles but not involving anal sphincter. (reVITALize)


name: Postneoadjuvant Therapy Stage IIIB Esophageal Adenocarcinoma AJCC v8

description: Stage IIIB includes: (T3, N1, M0); (T0-3, N2, M0); (T4a, N0, M0). T0: No evidence of primary tumor. T1: Tumor invades the lamina propria, muscularis mucosae, or submucosa. T2: Tumor invades the muscularis propria. T3: Tumor invades adventitia. T4a: Tumor invades the pleura, pericardium, azygos vein, diaphragm, or peritoneum. N0: No regional lymph node metastasis. N1: Tumor with metastasis in one or two regional lymph nodes. N2: Tumor with metastasis in three to six regional lymph nodes. M0: No distant metastasis. (AJCC 8th ed.)


name: Merkel cell carcinoma of left upper eyelid, including canthus

description: Evidence of Merkel cell carcinoma of left upper eyelid including the canthus.


Hypertriglyceridemia, CTCAE

description: A disorder characterized by laboratory test results that indicate an elevation in the concentration of triglyceride concentration in the blood.


name: Grade 5 Genitourinary Stoma Stricture or Stenosis, CTCAE


name: Grade 3 Lens Intra-Operative Injury, CTCAE


Recurrent Gangliocytoma

description: The reemergence of gangliocytoma after a period of remission.


name: Right Posterolateral Basal Peripheral Zone of Prostate

description: The region of the prostate that is located on the anatomical right side of the posterolateral portion of the basal division of the peripheral zone.


Low Weight Gain in Pregnancy

description: In a woman with a normal weight pre-pregnancy body mass index (BMI), i.e. 18.5-24.9, the weight gained during pregnancy does not exceed a total weight gain of 25 lbs. In a woman with an underweight pre-pregnancy body mass index (BMI), i.e. less than 18.5, the weight gained during pregnancy does not exceed a total weight gain of 28 lbs. In a woman with an overweight pre-pregnancy body mass index (BMI), i.e. 25.0-29.9, the weight gained during pregnancy does not exceed a total weight gain of 15 lbs. In a woman with an obese pre-pregnancy body mass index (BMI), i.e. greater than 30, the weight gained during pregnancy does not exceed a total weight gain of 11 lbs. These standards are supported for the whole population irrespective of height, race or ethnicity.


Gallbladder Neuroendocrine Tumor G3

description: A well differentiated, high grade neoplasm with neuroendocrine differentiation that arises from the gallbladder. The Ki-67 index is higher than 20%.


Edge Smearing Artifact

description: An edge artifact that results in image blurring.


name: Blood coagulation disorder due to liver disease

description: A disorder of blood clotting that is attributable to a deficiency in liver function.


Atrial Fibrillation, CTCAE

description: A disorder characterized by a dysrhythmia without discernible P waves and an irregular ventricular response due to multiple reentry circuits. The rhythm disturbance originates above the ventricles.


Pathological Gynecomastia

description: Gynecomastia that is due to exogenous substances or disease processes.


name: Rheumatoid Arthritis without Rheumatoid Factor, Right Ankle and Foot

description: Evidence of rheumatoid arthritis without rheumatoid factor in the right ankle and foot.


Grade 1 Uveitis, CTCAE

description: Anterior uveitis with trace cells


name: Other Psychoactive Substance Abuse with Withdrawal, Uncomplicated

description: Evidence of other psychoactive substance abuse with withdrawal, uncomplicated not specified elsewhere.


Pedunculated conjunctival papilloma

description: A papilloma that arises from the conjunctival squamous epithelium. It is associated with human papillomavirus infection.


Benign Intracranial Neoplasm

description: A neoplasm that involves the intracranial area and is characterized by the absence of atypical or malignant cytological and architectural features, and absence of invasive features or metastatic potential.


Other specified nontoxic goiter

description: Evidence of other specified non-toxic goiter not specified elsewhere.


name: Clinical Stage IVB Esophageal Adenocarcinoma AJCC v8

description: Stage IVB includes: Any T, Any N, M1. M1: Distant metastasis. (AJCC 8th ed.)


name: Atherosclerosis of Autologous Vein Bypass Graft(s) of the Extremities with Gangrene, Right Leg

description: Evidence of atherosclerosis of autologous vein bypass graft(s) of the extremities with gangrene in the right leg.


name: Major Salivary Gland Cancer Pathologic Distant Metastasis TNM Finding v6

description: A pathologic finding about one or more characteristics of major salivary gland cancer, following the rules of the TNM AJCC v6 classification system as they pertain to distant metastases.


Grade 2 Obstruction Gastric, CTCAE

description: Symptomatic; altered GI function; limiting instrumental ADL


Dysphagia, CTCAE

description: A disorder characterized by difficulty in swallowing.


Neonatal Coagulation Disorder, AE

description: An adverse event in a newborn characterized by abnormal blood clotting or bleeding.


Grade 4 Duodenal Infection, CTCAE

description: Life-threatening consequences; urgent intervention indicated


name: Anal or Perianal Infection with Unknown Absolute Neutrophil Count, CTCAE


Chronic Insomnia

description: Insomnia that has persisted at least one month.


Grade 1 Libido Decreased, CTCAE

description: Decrease in sexual interest not adversely affecting relationship


Grade 5 Stevens-Johnson Syndrome, CTCAE

description: Death


New Onset Diabetes After Transplant

description: Development of diabetes after transplant, usually associated with calcineurin inhibitor use.


name: Grade 4 Other Allergy and Immunology, CTCAE


Localized Prostate Carcinoma

description: A carcinoma that arises from the prostate and has not spread to other anatomic sites.


name: Benign Ovarian Partly Luteinized Thecoma


name: Metastatic Malignant Nongerminomatous Germ Cell Tumor

description: A malignant nongerminomatous germ cell tumor that has spread from its original site of growth to another anatomic site.


name: Grade 1 Associated with the Teeth, CTCAE


Recurrent Meningioma

description: The reemergence of a meningioma after a period of remission.


Grade 2 Abdominal Infection, CTCAE

description: Oral intervention indicated (e.g., antibiotic, antifungal, or antiviral)


name: Upper Gastrointestinal Hemorrhage NOS, CTCAE


name: Jejunum and Ileum Neuroendocrine Tumor pM1c TNM Finding v8

description: Jejunum and ileum neuroendocrine tumor with both hepatic and extrahepatic metastases. (from AJCC 8th Ed.)


U2AF1 Gene Mutation Negative

description: A genetic finding indicating that U2AF1 gene mutations have not been detected in a sample.


Well Differentiated Malignant Neoplasm

description: A malignant neoplasm with morphological features reminiscent of the tissue from which it arose.


Subglottic Cancer pT4a TNM Finding v8

description: Subglottic cancer with moderately advanced local disease. Tumor invades cricoid or thyroid cartilage and/or invades tissues beyond the larynx (e.g., trachea, soft tissues of neck including deep extrinsic muscles of the tongue, strap muscles, thyroid, or esophagus). (from AJCC 8th Ed.)


Grade 2 Atelectasis, CTCAE

description: Symptomatic (e.g., dyspnea, cough); medical intervention indicated (e.g., chest physiotherapy, suctioning); bronchoscopic suctioning


name: Mechanical Breakdown of Heart Valve Prosthesis, Sequela

description: Evidence of mechanical breakdown of heart valve prosthesis, sequela.


Penile Cancer cM0 TNM Finding v8

description: Penile cancer without evidence of distant metastasis. (from AJCC 8th Ed.)


name: Diseases of the Nervous System Complicating Pregnancy, First Trimester

description: Evidence of diseases of the nervous system complicating pregnancy in the first trimester.


name: Morbid (Severe) Obesity due to Excess Calories

description: Evidence of morbid (severe) obesity due to excess calories.


name: Other Reactive Arthropathies, Left Ankle and Foot

description: Evidence of other reactive arthropathies in the left ankle and foot not specified elsewhere.


Bladder Cancer pT2b TNM Finding v6

description: Bladder cancer with invasion into the deep muscle layer. (from AJCC 6th Ed.)


name: Lip and Oral Cavity Cancer Pathologic Primary Tumor TNM Finding v6

description: A pathologic finding about one or more characteristics of lip and oral cavity cancer, following the rules of the TNM AJCC v6 classification system as they pertain to staging of the primary tumor.


name: Ampulla of Vater Neuroendocrine Neoplasm

description: A neoplasm with neuroendocrine differentiation that arises from the ampulla of Vater and periampullary region. It includes neuroendocrine tumors (well-differentiated neuroendocrine neoplasms) and neuroendocrine carcinomas (poorly differentiated neuroendocrine neoplasms).


name: Grade 5 Nasal Cavity and Paranasal Sinus Reactions, CTCAE


EGFR Negative

description: An indication that EGFR expression has not been detected in a sample.


name: Grade 2 Upper Extremity Intra-Operative Injury, CTCAE


Ovoid Nodule

description: Nodule shape conforming to a roughly ovoid shape, in which the perpendicular diameters are dissimilar (there being a long diameter and a short diameter that differ by at least 30 percent).


name: Maxillary Sinus Cancer pT1 TNM Finding v6 and v7

description: Maxillary sinus cancer with tumor limited to the maxillary sinus mucosa with no erosion or destruction of bone.  (from AJCC 6th and 7th Eds.)


name: Grade 2 Biliary Tree Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


Ovarian Leydig Cell Hyperplasia

description: An increased number of Leydig cells in the hilar region of the ovary. (WHO 2020)


name: Grade 4 Liver Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


name: Grade 1 Stomach Intra-Operative Injury, CTCAE


Bladder Cancer pT3a TNM Finding v8

description: Bladder cancer with tumor invading perivesical soft tissue, microscopically. (from AJCC 8th Ed.)


name: Thyroid Cancer pT3 TNM Finding v6 and v7

description: Thyroid cancer with a tumor size greater than 4 cm in greatest dimension and limited to the thyroid gland, or a tumor of any size with minimal extrathyroid extension (e.g., extension to sternothyroid muscle or perithyroid soft tissues).  (from AJCC 6th and 7th Eds.)


name: Grade 5 Wound Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


Supraglottic Cancer pT3 TNM Finding v7

description: Supraglottic cancer with tumor limited to larynx with vocal cord fixation and/or invading any of the following: postcricoid area, preepiglottic space, paraglottic space, and/or inner cortex of thyroid cartilage. (from AJCC 7th Ed.)


name: Grade 1 Cardiac Troponin T Increased, CTCAE

description: Levels above the upper limit of normal and below the level of myocardial infarction as defined by the manufacturer


name: Grade 3 External Ear Infection with Unknown Absolute Neutrophil Count, CTCAE


name: PSA Doubling Time Less than or Equal to 12 Months

description: An indication that the number of months that a subject's blood concentration of prostate specific antigen took to double was twelve months or less.


Stage IV Merkel Cell Carcinoma AJCC v7

description: Stage IV includes: Any T, Any N, M1.  M1: Metastasis beyond regional lymph nodes. (AJCC 7th Ed.)


Stage 0 Anal Cancer AJCC v8

description: Stage 0 includes: Tis, N0, M0. Tis: High-grade squamous intraepithelial lesion (previously termed carcinoma in situ, Bowen disease, anal intraepithelial neoplasia II-III, high-grade anal intraepithelial neoplasia). N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 8th ed.)


Metastatic Endometrial Carcinoma

description: A carcinoma that arises from the endometrium and has metastasized to another anatomic site.


Grade 5 Prostate Infection, CTCAE

description: Death


name: Pancreatic Neuroendocrine Tumor pT1 TNM Finding v8

description: Pancreatic neuroendocrine tumor limited to the pancreas and measuring less than 2 cm. Limited to the pancreas means there is no invasion of adjacent organs (stomach, spleen, colon, adrenal gland) or the wall of large vessels (celiac axis or the superior mesenteric artery). Extension of tumor into peripancreatic adipose tissue is not a basis for staging. (from AJCC 8th Ed.)


Grade 2 Irritability, CTCAE

description: Moderate; limiting instrumental ADL; increased attention indicated


Grade 3 Soft Tissue Infection, CTCAE

description: IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated


Grade 1 Hyperglycemia, CTCAE

description: Abnormal glucose above baseline with no medical intervention


name: Carcinoma of the Eyelid pNX TNM Finding v7

description: Carcinoma of the eyelid in which the regional lymph nodes cannot be assessed.  (from AJCC 7th Ed.)


name: Angiodysplasia of Stomach and Duodenum with Bleeding

description: Evidence of angiodysplasia of stomach and duodenum with bleeding.


name: manic episode without psychotic symptoms - moderate

description: Evidence of manic episode without psychotic symptoms, moderate.


name: Salivary Infection with Unknown Absolute Neutrophil Count, CTCAE


Malignant Neoplasm of Right Choroid

description: Evidence of a malignant neoplasm of the right choroid.


name: Appendiceal Carcinoid Pathologic Regional Lymph Nodes TNM Finding v7

description: A pathologic finding about one or more characteristics of appendiceal carcinoid, following the rules of the TNM AJCC v7 classification system as they pertain to staging of regional lymph nodes.


name: Grade 4 Cranial Nerve X Intra-Operative Injury, CTCAE


Grade 1 Glucosuria, CTCAE

description: Present


name: Fallopian Tube Cancer Pathologic TNM Finding v7

description: A pathologic finding about one or more characteristics of fallopian tube cancer, following the rules of the TNM AJCC v7 classification system.


name: Stage III Cutaneous T-Cell Non-Hodgkin Lymphoma


PDGFRA Gene Mutation Negative

description: A genetic finding indicating that PDGFRA gene mutations have not been detected in a sample.


Additional Medication Required

description: Patient required additional medication or additional dose of existing medication.


name: Grade 3 Wound Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


Grade 2 Tremor, CTCAE

description: Moderate symptoms; limiting instrumental ADL


name: Rheumatoid Polyneuropathy with Rheumatoid Arthritis of Left Shoulder

description: Evidence of rheumatoid polyneuropathy with rheumatoid arthritis of left shoulder.


name: Other Specified Diabetes Mellitus with Proliferative Diabetic Retinopathy with Traction Retinal Detachment not Involving the Macula, Unspecified Eye

description: Evidence of other specified diabetes mellitus with proliferative diabetic retinopathy with traction retinal detachment not involving the macula, unspecified eye not specified elsewhere.


Digestive System Hodgkin Lymphoma

description: A Hodgkin lymphoma that arises from any part of the digestive system, with the bulk of the disease localized to that site.


Felty's Syndrome, Right Hip

description: Evidence of Felty's syndrome in the right hip.


Enhancing Lesion

description: A well-defined area of unequivocally increased signal intensity on MRI or CT scan images compared with the normal-appearing surrounding tissues, following intravenous injection of an enhancing agent.


Felty's Syndrome, Left Hand

description: Evidence of Felty's syndrome in the left hand.


Refractory Skin Squamous Cell Carcinoma

description: Skin squamous cell carcinoma that does not respond to treatment.


name: Gastric Neuroendocrine Tumor pTX TNM Finding v8

description: Gastric neuroendocrine tumor in which the primary tumor cannot be assessed. (from AJCC 8th Ed.)


name: Simple Hamartoma of the Retinal Pigment Epithelium

description: A retinal hamartoma that involves only the retinal pigment epithelium. (WHO 2018)


name: Other Stimulant Dependence with Intoxication Delirium

description: Evidence of other stimulant dependence with intoxication delirium not specified elsewhere.


Acute Myeloid Leukemia with del(17p)

description: Acute myeloid leukemia associated with deletion of the short arm of chromosome 17 [del(17p)].


Other Cardiovascular Syphilis

description: Evidence of other cardiovascular syphilis not specified elsewhere.


Other sphingolipidosis

description: Evidence of other sphingolipidosis not specified elsewhere.


mCode Non-Neoplastic Disease/Finding

description: Terminology related to non-neoplastic diseases and findings that was developed to support the efforts of Minimal Common Oncology Data Elements (mCode), a data standard designed to increase high-quality data for all cancer types.


Lung Cancer cM0 TNM Finding v7

description: Lung cancer without evidence of distant metastasis. (from AJCC 7th Ed.)


name: Extragonadal primary germ cell tumor mixed stage II


Neonatal Complication

description: A difficulty or problem that occurs at or just after delivery of an infant that can jeopardize the health of the infant.


name: Testicular Cancer Pathologic Regional Lymph Nodes TNM Finding v8

description: A pathologic finding about one or more characteristics of testicular cancer, following the rules of the TNM AJCC v8 classification system as they pertain to staging of regional lymph nodes.


Refractory Myxoid Liposarcoma

description: Myxoid liposarcoma that does not respond to treatment.


1-33 Percent Affected Area of Interest

description: A radiographic finding indicating the area of interest is 1/3 or less affected.


name: Esophageal Adenocarcinoma by AJCC v7 Stage

description: A term that refers to the staging of esophageal adenocarcinoma according to the American Joint Committee on Cancer, 7th edition.


name: Colorectal Cancer pTis Lamina Propria Invasion TNM Finding

description: Colorectal cancer in situ involving the lamina propria (intramucosal) without extension through the muscularis mucosa into the submucosa. (from CAP Colorectal Cancer Protocol-January 2005 Revision)


Grade 5 Delusions, CTCAE

description: Death


name: Sedative, Hypnotic or Anxiolytic Dependence, in Remission

description: Evidence of sedative, hypnotic or anxiolytic dependence, in remission.


Subcutaneous Disorder

description: A disorder of the subcutaneous tissue.


name: Carcinoma in situ of other parts of cervix

description: Evidence of carcinoma in situ of other parts of cervix.


name: Undersocialized conduct disorder, aggressive type


name: Malignant Neoplasm of Overlapping Sites of Left Male Breast

description: Evidence of a malignant neoplasm of overlapping sites of the left male breast.


CD14 Negative

description: An indication that CD14 expression has not been detected in a sample.


name: Locally Advanced Biliary Tract Carcinoma

description: Carcinoma that arises from the intrahepatic, hilar, extrahepatic bile ducts, cystic duct, or gallbladder and has spread to nearby tissues or lymph nodes.


name: Radiating Chest Pain Along Left Midclavicular Line

description: The location of the radiating chest pain is along the left midclavicular line.


MET Gene Amplification Negative

description: An indication that amplification of the MET gene was not detected in a sample.


Other lacunar syndromes

description: Evidence of other lacunar syndromes not specified elsewhere.


name: Cocaine Abuse with Unspecified Cocaine-Induced Disorder

description: Evidence of cocaine abuse with unspecified cocaine-induced disorder.


name: Refractory Endometrial Transitional Cell Carcinoma

description: Endometrial transitional cell carcinoma that is resistant to treatment.


Recurrent Appendix Carcinoma

description: The reemergence of appendix carcinoma after a period of remission.


Kidney Schwannoma

description: A rare schwannoma arising from the kidney.


name: Grade 4 Postoperative Thoracic Procedure Complication, CTCAE

description: Life-threatening airway compromise; urgent intervention indicated (e.g., tracheotomy or intubation)


FOXO1 Fusion Negative

description: An indication that the expression of a fusion involving FOXO1 has not been detected in a sample.


name: Melanoma of the Conjunctiva pT2b TNM Finding v7

description: Melanoma of the palpebral, forniceal, or caruncular conjunctiva with tumor measuring more than 0.5 mm but not more than 1.5 mm in thickness with invasion of the substantia propria.  (from AJCC 7th Ed.)


Total Bilirubin Level Finding

description: A finding that indicates the amount of total bilirubin in a sample.


Treatment-Emergent Adverse Event

description: A situation that emerges during treatment, having been absent pretreatment, or worsens relative to the pretreatment state. (ICH)


Childhood Neuroendocrine Neoplasm

description: A neuroendocrine neoplasm that occurs during childhood.


Eyelid Carcinoma pT3b TNM Finding v8

description: Eyelid carcinoma with tumor measuring more than 20 mm but 30 mm or less in greatest dimension with invasion of the tarsal plate or eyelid margin. (from AJCC 8th Ed.)


name: Acute Peptic Ulcer, Site Unspecified, without Hemorrhage or Perforation

description: Evidence of an acute peptic ulcer, site unspecified, without hemorrhage or perforation.


Congenital complete heart block

description: A disorder characterized by an electrocardiographic finding of a complete atrioventricular block that manifests during fetal life or soon after birth. It may be isolated or associated with other congenital heart defects. Isolated congenital complete atrioventricular block may be associated with maternal connective tissue disorders.


name: DYSKERATOSIS CONGENITA, AUTOSOMAL DOMINANT 2

description: Dyskeratosis congenita caused by mutation(s) in the TERT gene, encoding telomerase reverse transcriptase.


name: Appendix Neuroendocrine Tumor by AJCC v7 Stage

description: A term that refers to the staging of an appendiceal neuroendocrine tumor, following the rules of the TNM AJCC v7 classification system.


name: Grade 1 CD4 Lymphocytes Decreased, CTCAE

description: <LLN-500/mm3; <LLN-0.5 x 10e9/L


name: Lugano Classification Stage IE Childhood Hodgkin Lymphoma AJCC v8

description: Stage IE: Single extralymphatic site in the absence of nodal involvement (rare in Hodgkin lymphoma). (from AJCC 8th Ed.)


name: Grade 4 Wound Infection with Unknown Absolute Neutrophil Count, CTCAE


Grade 2 Vital Capacity Abnormal, CTCAE

description: <75-50% of predicted value; limiting instrumental ADL


Prostate Cancer pT2 TNM Finding v8

description: Prostate cancer which is organ confined. (from AJCC 8th Ed.)


Metaplastic meningioma

description: A WHO grade I meningioma characterized by the presence of a prominent mesenchymal component. The mesenchymal component may be osseous, cartilaginous, myxoid, lipomatous, or a mixture of mesenchymal elements.


name: Postneoadjuvant Therapy Stage IVA Esophageal Adenocarcinoma AJCC v8

description: Stage IVA includes: (T4a, N1-2, M0); (T4a, NX, M0); (T4b, N0-2, M0); (Any T, N3, M0). T4a: Tumor invades the pleura, pericardium, azygos vein, diaphragm, or peritoneum. T4b: Tumor invades other adjacent structures, such as the aorta, vertebral body, or airway. NX: Regional lymph nodes cannot be assessed. N0: No regional lymph node metastasis. N1: Tumor with metastasis in one or two regional lymph nodes. N2: Tumor with metastasis in three to six regional lymph nodes. N3: Tumor with metastasis in seven or more regional lymph nodes. M0: No distant metastasis. (AJCC 8th ed.)


Stage IV Bone Cancer AJCC v7

description: Stage IV includes: IVA (Any T, N0, M1a, Any G); IVB (Any T, N1, Any M, Any G); (Any T, Any N, M1b, Any G).  N0: No regional lymph node metastasis.  N1: Regional lymph node metastasis.  M1a: Distant metastasis to lung.  M1b: Metastasis to other distant sites. (AJCC 7th ed.)


name: Unknown Primary Tumor cN3b TNM Finding v8

description: Unknown primary tumor with metastasis in any cervical node(s) with clinically overt ENE(+) (ENEc). ENEc is defined as invasion of skin, infiltration of musculature, dense tethering or fixation to adjacent structures, or cranial nerve, brachial plexus, sympathetic trunk, or phrenic nerve invasion with dysfunction. (from AJCC 8th Ed.)


name: Small Bowel Infection with Unknown Absolute Neutrophil Count NOS, CTCAE


Grade 5 Meningismus, CTCAE

description: Death


name: Atherosclerosis of Native Arteries of Left Leg with Ulceration of Other Part of Foot

description: Evidence of atherosclerosis of native arteries of left leg with ulceration of other part of foot.


Pulmonary toxicity

description: Toxicity that impairs or damages the lung(s). This condition is often caused by the administration of a pharmaceutical agent that causes damage to the lungs.


name: Grade 5 Ileum Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


name: Bladder Cancer Pathologic Primary Tumor TNM Finding v6

description: A pathologic finding about one or more characteristics of bladder cancer, following the rules of the TNM AJCC v6 classification system as they pertain to staging of the primary tumor. TNM pathologic primary tumor findings are based on clinical findings supplemented by histopathologic examination of one or more tissue specimens acquired during surgery.


Grade 3 Obstruction Gastric, CTCAE

description: Hospitalization indicated; invasive intervention indicated; limiting self care ADL


name: Decreased Carbon Monoxide Diffusing Capacity

description: A lung function test result in which the lung capacity to absorb carbon monoxide is decreased.


Prostate Cancer pT3a TNM Finding v8

description: Prostate cancer with extraprostatic extension (unilateral or bilateral) or microscopic invasion of bladder neck. (from AJCC 8th Ed.)


MDM2 Gene Amplification Negative

description: An indication that amplification of the MDM2 gene was not detected in a sample.


Colon Polyp Observed During Examination

description: Direct observation of a colon polyp upon examination, during surgical procedure, or colonoscopy.


Grade 3 Anal Necrosis, CTCAE

description: TPN or hospitalization indicated; invasive intervention indicated


Body Mass Index 38.0-38.9, Adult

description: Evidence of a body mass index of 38.0-38.9 in the adult.


Childhood Blue Nevus

description: A blue nevus that occurs during childhood.


name: Other Specified Diabetes Mellitus with Other Oral Complications

description: Evidence of other specified diabetes mellitus with other oral complications not specified elsewhere.


45,XO with Y Chromosomal Material

description: An abnormal sex chromosome karyotype where the individual is missing a second X chromosome and has some chromosomal material from the Y chromosome. The normal autosomal karyotype is present.


name: Melanoma in situ of left lower eyelid, including canthus

description: Evidence of melanoma in situ of left lower eyelid including the canthus.


Grade 5 Hyponatremia, CTCAE

description: Death


name: Atherosclerosis of Native Arteries of Right Leg with Ulceration of Heel and Midfoot

description: Evidence of atherosclerosis of native arteries of right leg with ulceration of heel and midfoot.


name: Grade 2 Surgical and Medical Procedures - Other, Specify, CTCAE

description: Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL


name: Atherosclerosis of Non-Autologous Biological Bypass Graft(s) of Right Leg with Ulceration of Other Part of Foot

description: Evidence of atherosclerosis of non-autologous biological bypass graft(s) of right leg with ulceration of other part of foot.


Joint Tuberculosis

description: Tuberculosis affecting a joint.


name: Grade 4 Other Blood and Bone Marrow, CTCAE


Malignant tumor of cloacogenic zone

description: Evidence of a malignant neoplasm of the cloacogenic zone.


Shading Artifact

description: An artifact that is due to a group of channels or views that deviate gradually from the true measurement.


name: Choroidal and Ciliary Body Melanoma pT4d TNM Finding v8

description: Choroidal and ciliary body melanoma, tumor size category 4 with ciliary body involvement and extraocular extension 5 mm or less in largest diameter. (from AJCC 8th Ed.)


Ureter Cancer by AJCC v7 Stage

description: A term that refers to the staging of ureter cancer according to the American Joint Committee on Cancer, 7th edition.


name: Grade 5 Fallopian Tube Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


name: Supraglottic Cancer pN2a TNM Finding v6 and v7

description: Supraglottic cancer with metastasis to a single ipsilateral lymph node, more than 3 cm, but not more than 6 cm in greatest dimension. (from AJCC 6th and 7th Eds.)


Elevated WT1

description: A finding indicating elevated concentrations of WT1 in a sample.


Bulky Nodal Disease

description: Bulk at an alternate site to the thorax defined as any mass measuring 10 cm or more by any imaging study.


Partial Response by Computed Tomography

description: A decrease in the size and extent of tissue involvement by cancer, based on CT scan and criteria-defined assessments.


Epidermal burn of skin

description: A painful injury to the epidermis due to chemical, friction, radiation or thermal exposure. The affected area appears red and blanches when touched.


name: Gastrointestinal Neuroendocrine Tumor Clinical TNM Finding v7

description: A clinical finding about one or more characteristics of gastrointestinal neuroendocrine tumor, following the rules of the TNM AJCC v7 classification system.  The clinical staging depends upon the anatomic extent and hormonal activity of the primary tumor, which can be ascertained by examination before treatment. (from AJCC 7th Ed.)


Grade 5 Capillary Leak Syndrome, CTCAE

description: Death


Foregut Neuroendocrine Tumor G1

description: A neuroendocrine tumor that arises from the esophagus, stomach, or duodenum.


name: Pleural Malignant Mesothelioma TNM Finding v8

description: A finding about one or more characteristics of pleural malignant mesothelioma, following the rules of the TNM AJCC v8 classification system. This classification system applies to pleural diffuse malignant mesothelioma only. Localized pleural malignant mesotheliomas and other primary tumors of the pleura are not included in this classification. (from AJCC 8th Ed.)


Radiating Chest Pain in Left Arm

description: The location of the radiating chest pain is in the left arm.


Stage IIIA Gallbladder Cancer AJCC v7

description: Stage IIIA includes: T3, N0, M0. T3: Tumor perforates the serosa (visceral peritoneum) and/or directly invades the liver and/or one other adjacent organ or structure, such as the stomach, duodenum, colon, pancreas, omentum, or extrahepatic bile ducts.  N0: No regional lymph node metastasis.  M0: No distant metastasis. (from AJCC 7th Ed.)


name: Conjunctival Melanoma cT2d TNM Finding v8

description: Conjunctival melanoma with caruncular tumor, and more than 1 quadrant of the nonbulbar conjunctiva involved. (from AJCC 8th Ed.)


Polycythaemia (excl rubra vera)

description: An increase in the concentration of red blood cells (hemoglobin) that is not caused by polycythemia vera.


name: Cerebral Infarction due to Unspecified Occlusion or Stenosis of Unspecified Vertebral Artery

description: Evidence of cerebral infarction due to an unspecified occlusion or stenosis of an unspecified vertebral artery.


name: Hypopharyngeal Cancer Pathologic Regional Lymph Nodes TNM Finding v6

description: hypopharyngeal cancer, following the rules of the TNM classification system as they pertain to staging of regional lymph nodes.


Global Partial Response in Lymph Nodes

description: Cumulative reduction of 50 percent or more of the sum of products of diameter of each abnormal lymph node at baseline and no new lymph node greater than 1.5 cm in the diameter of the long axis or greater than 1.0 cm in the diameter of the short axis if the long axis is 1-1.5 cm diameter.


name: Grade 5 Stomach Infection with Unknown Absolute Neutrophil Count, CTCAE


name: Grade 2 Other Blood and Bone Marrow, CTCAE


Malignant carcinoid tumor of kidney

description: Evidence of a malignant carcinoid tumor of the kidney.


Hemiplegia, Flaccid

description: Evidence of flaccid hemiplegia affecting the unspecified side.


name: Stage IIIC Uterine Corpus Cancer AJCC v8

description: Stage IIIC includes: IIIC1: T1-T3, N1/N1mi/N1a, M0; IIIC2: T1-T3, N2/N2mi/N2a, M0. T1: Uterine corpus carcinoma or carcinosarcoma with tumor confined to the corpus uteri, including endocervical glandular involvement. T2: Uterine corpus carcinoma or carcinosarcoma with tumor invading the stromal connective tissue of the cervix but not extending beyond the uterus. Does not include endocervical glandular involvement. T3: Uterine corpus carcinoma or carcinosarcoma with tumor involving serosa, adnexa, vagina, or parametrium. N1: Regional lymph node metastasis to pelvic lymph nodes. N1mi: Regional lymph node metastasis (greater than 0.2 mm but nor greater than 2.0 mm in diameter) to pelvic lymph nodes. N1a: Regional lymph node metastasis (greater than 2.0 mm in diameter) to pelvic lymph nodes. N2: Regional lymph node metastasis to para-aortic lymph nodes, with or without positive pelvic lymph nodes. N2mi: Regional lymph node metastasis (greater than 0.2 mm but not greater than 2.0 mm in diameter) to para-aortic lymph nodes, with or without positive pelvic lymph nodes. N2a: Regional lymph node metastasis (greater than 2.0 mm in diameter) to para-aortic lymph nodes, with or without positive pelvic lymph nodes. M0: No distant metastasis. (from AJCC 8th Ed.)


Grade 5 Ventricular Arrhythmia, CTCAE

description: Death


description: Thrombotic microangiopathy that presents in some patients undergoing hematopoietic stem cell transplantation (HSCT). Though similar in presentation to thrombotic thrombocytopenic purpura (TTP) and atypical hemolytic uremic syndrome (aHUS), transplant-associated thrombotic microangiopathy (TA-TMA) is a distinct disorder. Several risk factors may be associated with TA-TMA, including high-dose chemotherapy, radiation therapy, HLA mismatch, use of calcineurin inhibitors, acute graft-versus-host disease (GVHD), and infections.


Corneal dellen

description: Corneal thinning just anterior to the limbus secondary to abnormal and/or irregular bulbar conjunctival contour.


name: Chest Pain in Left Fourth Intercostal Space

description: The location of the chest pain is within the fourth intercostal space on the left side.


name: Pancreatic Neuroendocrine Tumor pN1 TNM Finding v8

description: Pancreatic neuroendocrine tumor with regional lymph node involvement. (from AJCC 8th Ed.)


Spindle cell melanoma, type B

description: A melanoma characterized by the presence of malignant spindle-shaped melanocytes with larger nuclei and distinct nucleoli. Representative example is the type B spindle cell uveal melanoma.


name: Grade 1 Soft Tissue NOS Intra-Operative Injury, CTCAE


name: Other malignant immunoproliferative diseases

description: Evidence of other malignant immunoproliferative diseases not specified elsewhere.


name: Esophageal Adenocarcinoma by AJCC v8 Stage

description: A term that refers to the staging of esophageal adenocarcinoma according to the American Joint Committee on Cancer, 8th edition.


Mesothelioma of other sites

description: Evidence of mesothelioma of other sites than specified.


Naevus Lipomatosus Superficialis

description: A rare developmental anomaly characterized by the presence of ectopic adipose tissue within the upper half of the dermis. (WHO 2018)


name: asymptomatic carrier of alpha-thalassemia

description: A condition in which a person has reduced protein production from one of the four alpha-globin alleles.


Stage IIIC Cervical Cancer FIGO 2018

description: Cervical carcinoma with involvement of pelvic and/or para-aortic lymph nodes, irrespective of tumor size and extent (with r and p notations). (FIGO 2018)


name: Grade 2 Breast Intra-Operative Injury, CTCAE


Recurrent Severe Aplastic Anemia

description: The reemergence of severe aplastic anemia after a period of remission.


name: Nasopharyngeal Cancer pTis TNM Finding v6 and v7

description: Nasopharyngeal cancer with a finding of carcinoma in situ. (from AJCC 6th and 7th Eds.)


name: Oropharyngeal Cancer Clinical TNM Finding v7

description: A clinical finding about one or more characteristics of oropharyngeal cancer, following the rules of the TNM AJCC v7 classification system.


name: alk-positive anaplastic large cell lymphoma of intrathoracic lymph nodes

description: Evidence of anaplastic large cell lymphoma that is ALK-Positive in the intrathoracic lymph nodes.