Quadriplegia, C5-C7 Incomplete

description: Evidence of quadriplegia, C5-C7 incomplete.


Grade 5 Infantile Apnea, AE

category: biolink:PhenotypicFeature biolink:DiseaseOrPhenotypicFeature biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing

description: An apneic adverse event in a newborn which results in death.


Grade 3 Fatigue, CTCAE

description: Fatigue not relieved by rest, limiting self care ADL


dyskeratosis congenita

category: biolink:Disease biolink:DiseaseOrPhenotypicFeature biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing

description: A rare genetic disorder characterized by nail dystrophy, reticulated skin pigmentation especially on the neck and chest, and oral leukoplakia.  In about half the cases mutations in the TERT, TERC, DKC1, or TINF2 genes are identified.  Patients are at an increased risk of developing bone marrow failure, myelodysplastic syndrome, leukemia, or cancer, especially in the head and neck region.


chronic hepatic failure with coma

description: Evidence of chronic hepatic failure with coma.


Chronic acquired lymphedema

description: A condition that is caused by trauma to the lymph system, which disrupts the normal flow of lymph fluid. This is most often due to surgery that requires lymph node removal or a large amount of lymph tissue. This disruption is especially apparent if the lymph nodes under the arm and arm and around the breast are compromised due to breast cancer surgery, diagnostic dissection, mastectomy, or radiation.


name: Diabetes Mellitus due to Underlying Condition with Periodontal Disease

description: Evidence of diabetes mellitus due to underlying condition with periodontal disease.


name: Occupational Artificial Smoke Machine Smoke Exposure

description: Occupational exposure to airborne gases and particulates during the operation of a machine that produces artificial smoke.


name: Grade 5 Neonatal Spontaneous Intestinal Perforation, AE

description: A spontaneous intestinal perforation (SIP) adverse event in a newborn which results in death.


name: Atherosclerosis of Unspecified Type of Bypass Graft(s) of the Extremities with Rest Pain, Left Leg

description: Evidence of atherosclerosis of unspecified type of bypass graft(s) of the extremities with rest pain in the left leg.


name: Other types of follicular lymphoma, lymph nodes of axilla and upper limb

description: Evidence of other types of follicular lymphoma in the lymph nodes of axilla and upper limb not specified elsewhere.


name: Grade 3 Central Nervous System Necrosis, CTCAE

description: Severe symptoms; medical intervention indicated


Grade 5 Otitis Externa, CTCAE

description: Death


name: Mycosis Fungoides and Sezary Syndrome B0b TNM Finding v8

description: Clone positive. Note: A T-cell clone is defined by polymerase chain reaction (PCR) or Southern blot analysis of the TCR gene. (from AJCC 8th Ed.)


name: Grade 2 Pharynx Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


Grade 4 Prolapse of Urostomy, CTCAE

description: Life-threatening consequences; urgent intervention indicated


Abdominal Infection, CTCAE

description: A disorder characterized by an infectious process involving the abdominal cavity.


name: Follicular Lymphoma Grade II, Lymph Nodes of Head, Face, and Neck

description: Evidence of follicular lymphoma grade II in the lymph nodes of head in the face in the and neck.


name: Chest Pain Along Right Middle Sternal Border

description: The location of the chest pain is along the right middle border of the sternum.


name: Acute Myeloid Leukemia with Myelodysplasia-Related Gene Mutations

description: A group of acute myeloid leukemias characterized by the presence of gene mutations that are associated with myelodysplasia.


Stage IV Prostate Cancer AJCC v6

description: Stage IV includes: (T4, N0, M0); (Any T, N1, M0); (Any T, Any N, M1) (Any G).  T4: Tumor is fixed or invades adjacent structures other than seminal vesicles: bladder neck, external sphincter, rectum, levator muscles, and/or pelvic wall.  N1: Metastasis in regional lymph node(s).  M1: Distant metastasis.  (AJCC 6th ed.)


name: General Disorders and Administration Site Conditions, CTCAE


name: Testicular Sertoli Cell Tumor, Lipid Rich Variant

description: A testicular Sertoli cell tumor in which the neoplastic cells have clear and vacuolated cytoplasm due to accumulation of intracytoplasmic lipids.


Grade 2 Dyspnea, CTCAE

description: Shortness of breath with minimal exertion; limiting instrumental ADL


Endometrial Dedifferentiated Carcinoma

description: A carcinoma that arises from the endometrium and is characterized by the presence of an undifferentiated carcinomatous component and a second component of either FIGO grade 1 or 2 endometrioid carcinoma.


Penile Cancer cN1 TNM Finding v7

description: Penile cancer with palpable mobile unilateral inguinal lymph node. (from AJCC 7th Ed.)


Adult Type Granulosa Cell Tumor

description: A low-grade malignant sex cord-stromal tumor occurring in the ovary and rarely in the testis. It is composed of granulosa cells in an often fibrothecomatous stroma. The neoplastic cells may form various patterns including the microfollicular, which is characterized by the presence of Call-Exner bodies, macrofollicular, insular, trabecular, and diffuse pattern. In females, it affects middle aged to post-menopausal women. Signs and symptoms include abdominal mass, hemoperitoneum, and ascites. Estrogenic and rarely androgenic manifestations may be present. The vast majority of cases present as stage I tumors; however, all tumors have a potential for aggressive clinical course. In males, it is reported in the age range of 16-76 years and the average age at presentation is 44 years. A minority of patients have gynecomastia. Metastases have been reported in a minority of patients.


name: Melanoma in Situ of Breast (Skin) (Soft Tissue)

description: Evidence of melanoma in situ of breast (skin) (soft tissue).


Uveal Melanoma cM1b TNM Finding v8

description: Uveal melanoma with largest diameter of the largest metastasis 3.1-8.0 cm. (from AJCC 8th Ed.)


name: Rheumatoid Lung Disease with Rheumatoid Arthritis of Right Ankle and Foot

description: Evidence of rheumatoid lung disease with rheumatoid arthritis of right ankle and foot.


name: Grade 2 Peripheral Sensory Nerve NOS Intra-Operative Injury, CTCAE


name: Grade 2 Tooth Development Disorder, CTCAE

description: Impairment correctable with oral surgery


Stage IA2 Cervical Cancer FIGO 2009

description: Cervical carcinoma measuring more than 3 mm and not more than 5 mm in depth. (FIGO 2009)


Lung Cancer pT3 TNM Finding v6

description: Lung cancer directly invading the chest wall (including superior sulcus tumors), diaphragm, mediastinal pleura or parietal pericardium, or a tumor of any size extending into the main bronchus less than 2 cm distal to the carina but without involvement of the carina, or a tumor of any size with atelectasis or obstructive pneumonitis involving the entire lung. (from AJCC 6th Ed.)


name: Other infective spondylopathies, cervicothoracic region

description: Evidence of other infective spondylopathies in the cervicothoracic region not specified elsewhere.


Grade 3 Lip Infection, CTCAE

description: IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated


name: Monoplegia of Upper Limb following Other Non-Traumatic Intracranial Hemorrhage Affecting Unspecified Side

description: Evidence of monoplegia of upper limb following other non-traumatic intracranial hemorrhage affecting unspecified side.


name: Follicular Lymphoma Grade I, Lymph Nodes of Head, Face, and Neck

description: Evidence of follicular lymphoma grade I in the lymph nodes of head in the face in the and neck.


name: Grade 2 Cranial Nerve X Intra-Operative Injury, CTCAE


name: Grade 5 Foreign Body Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


A1 Hydronephrosis

description: Antenatal hydronephrosis with the following clinical findings: 1) an anterior-posterior renal pelvis diameter (APRPD) of 4 to less than 7 mm at less than 28 weeks, 2) to less than10 mm at greater than or equal to 28 weeks, and 3) may have central calyceal dilation. (Adapted from: Hiep T. Nguyen, Carol B. Benson, Bryann Bromley, Jeffrey B. Campbell, Jeanne Chow, Beverly Coleman, Christopher Cooper, Jude Crino, Kassa Darge, C.D. Anthony Herndon, Anthony O. Odibo, Michael J.G. Somers, Deborah R. Stein; Multidisciplinary consensus on the classification of prenatal and postnatal urinary tract dilation (UTD classification system); Pediatric Urology; December 2014 Volume 10, Issue 6, Pages 982-998)


name: Atherosclerosis of Non-Biological Bypass Graft(s) of the Extremities with Gangrene, Bilateral Legs

description: Evidence of atherosclerosis of non-biological bypass graft(s) of the extremities with gangrene in both legs.


Liver Cancer pT2 TNM Finding v6

description: Liver cancer with a solitary tumor of any size with vascular invasion, or with multiple tumors none of which are more than 5 cm in size. (from AJCC 6th Ed.)


name: Grade 2 Pharynx Mucositis or Stomatitis by Clinical Examination Classification, CTCAE


name: Malignant Neoplasm of Central Portion of Right Female Breast

description: Evidence of a malignant neoplasm of the central portion of right female breast.


Bone Lucency

description: A radiologic finding of an area of bone resulting from decreased absorption of the radiation used in the imaging process.


Grade 5 Cecal Hemorrhage, CTCAE

description: Death


name: Grade 2 Bladder Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


name: Primary Mediastinal (Thymic) Large B-Cell Lymphoma, Extranodal and Solid Organ Sites

description: Evidence of primary mediastinal (thymic) large B-cell lymphoma in the extranodal and solid organ sites.


name: Childhood Benign Genitourinary System Neoplasm

description: A childhood neoplasm that arises from any part of the genitourinary system and is characterized by the absence of atypical or malignant cytological and architectural features, and absence of invasive features or metastatic potential.


Grade 4 Pulmonary Valve Disease, CTCAE

description: Life-threatening consequences; urgent intervention indicated (e.g., valve replacement, valvuloplasty)


name: Gestational Trophoblastic Neoplasm cM1 TNM Finding v8

description: Gestational trophoblastic neoplasm with distant metastasis. (from AJCC 8th Ed.)


Impaired judgement

description: Reduced ability to plan, poor decision making.


Retinoblastoma pT4 TNM Finding v7

description: Retinoblastoma with tumor invading optic nerve to resection line or exhibiting extra-ocular extension elsewhere. (from AJCC 7th Ed.)


Grade 4 Tracheal Stenosis, CTCAE

description: Life-threatening airway compromise; urgent intervention indicated (e.g., tracheotomy or intubation)


name: Skin Squamous Cell Carcinoma or Other Skin Carcinomas cM0 TNM Finding v7

description: Skin squamous cell carcinoma or other skin carcinomas without distant metastases. (from AJCC 7th Ed.)


name: Post-Dysenteric Arthropathy, Left Ankle and Foot

description: Evidence of post-dysenteric arthropathy in the left ankle and foot.


name: Invasive Lipid-Rich Urothelial Carcinoma

description: Invasive urothelial carcinoma characterized by the presence of lipid laden tumor cells.


Grade 2 Hepatic Pain, CTCAE

description: Moderate pain; limiting instrumental ADL


name: Grade 4 Portal Vein Intra-Operative Injury, CTCAE


name: Appendix Neuroendocrine Tumor pN0 TNM Finding v8

description: Appendix neuroendocrine tumor without regional lymph node metastasis. (from AJCC 8th Ed.)


Fourth Degree Perineal Laceration

description: Injury to perineum involving anal sphincter complex and internal anal sphincter and anal epithelium. (reVITALize)


Sickle Cell-SS Disease

description: A variant of sickle cell disease due to homozygosity of the E6V mutation, amino acid substitution of valine for glutamic acid in the sixth position of the beta chain, resulting in the production of hemoglobin S from both alleles.


Steroid-induced myopathy

description: A non-neoplastic disorder affecting the skeletal muscles. It is caused by damage to muscle fibers either by excessive intake of corticosteroids (steroid treatment) or high levels of endogenous corticosteroids due to hormonal abnormalities. Patients usually present with weakness mainly in the proximal muscles of the upper and lower extremities and the neck flexors.


name: Carcinoma of the Eyelid pM1 TNM Finding v7

description: Carcinoma of the eyelid with distant metastasis. (from AJCC 7th Ed.)


name: Grade 3 Upper Extremity Intra-Operative Injury, CTCAE


name: Grade 1 Left Ventricular Systolic Dysfunction, CTCAE


name: Cutaneous Squamous Cell Carcinoma of the Head and Neck pN2 TNM Finding v8

description: Cutaneous squamous cell carcinoma of the head and neck with metastasis in a single ipsilateral lymph node, 3 cm or smaller in greatest dimension and ENE(+); or metastasis in a single ipsilateral lymph node larger than 3 cm but not larger than 6 cm in greatest dimension and ENE(-); or metastases in multiple ipsilateral lymph nodes, none larger than 6 cm in greatest dimension and ENE(-); or metastases in bilateral or contralateral lymph nodes, none larger than 6 cm in greatest dimension and ENE(-).  (from AJCC 8th Ed.)


name: Type 1 Diabetes Mellitus with Severe Nonproliferative Diabetic Retinopathy with Macular Edema, Bilateral

description: Evidence of type 1 diabetes mellitus with severe nonproliferative diabetic retinopathy with macular edema that is bilateral.


Grade 3 Small Intestine Ulcer, CTCAE

description: Severely altered GI function; TPN indicated; elective invasive intervention indicated; limiting self care ADL


name: Enteropathic Arthropathies, Unspecified Knee

description: Evidence of enteropathic arthropathies in an unspecified knee.


Neonatal Early-Onset Sepsis

description: An infectious disorder of newborn infants that is characterized by a systemic inflammatory response within 72 hours of life and is most commonly caused by bacteria.


name: Hypopharyngeal Cancer cM0 TNM Finding v8

description: Hypopharyngeal cancer without evidence of distant metastasis. (from AJCC 8th Ed.)


name: Grade 1 Gastrointestinal Stoma Leak, CTCAE


Grade 3 Diarrhea, CTCAE

description: Increase of >=7 stools per day over baseline; hospitalization indicated; severe increase in ostomy output compared to baseline; limiting self care ADL


Grade 3 Prostate Infection, CTCAE

description: IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated


name: Juvenile Arthritis, Unspecified, Unspecified Knee

description: Evidence of unspecified juvenile arthritis in the knee.


T1b3 TNM Finding

description: A general term that refers to a TNM finding of a primary tumor limited to the site of growth.  The definition of T1b3 TNM finding depends on the specific type of cancer that it refers to; for example, for carcinoma of the cervix uteri it refers to a primary tumor that is strictly confined to the cervix (extension to the corpus should be disregarded) that is greater than 4 cm in greatest dimension.


Rheumatic aortic valve disease

description: A disorder of the aortic valve secondary to rheumatic fever.


name: Grade 1 Hypoxic Ischemic Encephalopathy, AE

description: An adverse event in a newborn clinically classified as perinatal asphyxia, but not resulting in encephalopathy.


Other Malignant Neuroendocrine Tumors

description: Evidence of other malignant neuroendocrine tumors not specified elsewhere.


name: Exocrine Pancreatic Cancer pM1 TNM Finding v8

description: Exocrine pancreatic cancer with distant metastasis. (from AJCC 8th Ed.)


Refractory Cervical Carcinoma

description: Cervical carcinoma that is resistant to treatment.


name: Localization-Related Symptomatic Epilepsy and Epileptic Syndromes with Complex Partial Seizures, Intractable, without Status Epilepticus

description: Evidence of localization-related symptomatic epilepsy and epileptic syndromes with complex partial seizures, without status epilepticus that does not respond optimally to treatment.


cannabis abuse with withdrawal

description: Evidence of cannabis abuse with withdrawal.


name: Merkel Cell Carcinoma Clinical Distant Metastasis TNM Finding v8

description: A clinical finding about one or more characteristics of Merkel cell carcinoma, following the rules of the TNM AJCC v8 classification system as they pertain to distant metastases.


Grade 5 Rectal Obstruction, CTCAE

description: Death


name: Sebaceous cell carcinoma of skin of left upper eyelid, including canthus

description: Evidence of sebaceous cell carcinoma of skin of left upper eyelid including the canthus.


name: Intrahepatic Bile Duct Biliary Intraepithelial Neoplasia

description: A neoplastic, non-invasive lesion that affects the intrahepatic bile duct epithelium.  It is characterized by the presence of atypical epithelial cells with an increased nuclear/cytoplasmic ratio, nuclear hyperchromasia, and loss of nuclear polarity.


name: Other Inflammatory Spondylopathies, Lumbosacral Region

description: Evidence of other inflammatory spondylopathies in the lumbosacral region not specified elsewhere.


46,XY Sex Reversal 2

description: Sex reversal in an individual with 46,XY karyotype caused by point mutations or deletions in the NR0B1 gene, encoding nuclear receptor subfamily 0 group B member 1.


name: Type 1 Diabetes Mellitus with Mild Nonproliferative Diabetic Retinopathy without Macular Edema, Bilateral

description: Evidence of type 1 diabetes mellitus with mild nonproliferative diabetic retinopathy without macular edema that is bilateral.


name: Grade 3 Intra-Abdominal Hemorrhage, CTCAE

description: Transfusion indicated; invasive intervention indicated; hospitalization


Thymic Tumor pT3 TNM Finding v8

description: Thymic tumor with direct invasion into any of the following: lung, brachiocephalic vein, superior vena cava, phrenic nerve, chest wall, or extrapericardial pulmonary artery or veins. (from AJCC 8th Ed.)


name: Prior Invasive Malignancy of Other Sites

description: A finding indicating the presence of a previously diagnosed malignant neoplasm infiltrating other, non-specified anatomic sites.


name: Nodular Sclerosis Classic Hodgkin Lymphoma, Intrapelvic Lymph Nodes

description: Evidence of nodular sclerosis classic Hodgkin lymphoma in the intrapelvic lymph nodes.


name: Left Anterior Apical Transition Zone of Prostate

description: The region of the prostate that is located on the anatomical left side of the anterior portion of the apical division of the transition zone.


Castration Levels of Testosterone

description: A finding of low concentrations of testosterone in a subject's serum that results from the use of surgical or chemical castration procedures.


name: Esophagus and Esophagogastric Junction Cancer pT2 TNM Finding v8

description: Esophagus and esophagogastric junction cancer with tumor invading the muscularis propria. (from AJCC 8th Ed.)


name: Gastrointestinal Stromal Tumor pTX TNM Finding v7

description: Gastrointestinal stromal tumor in which the primary tumor cannot be assessed. (from AJCC 7th Ed.)


Vulvar Cancer pN1 TNM Finding v7

description: Vulvar cancer with one or two lymph node metastasis each measuring 5 mm or less, or one lymph node metastasis measuring 5 mm or greater. (from AJCC 7th Ed.)


Hemoglobin S/O-Arab Heterozygote

description: A laboratory finding indicating that the subject expresses abnormal hemoglobin containing 2 variant forms of the hemoglobin subunit beta protein (HBB). One HBB protein variant has the amino acid substitution glutamic acid to valine at residue 6, which is associated with the formation of hemoglobin S (HbS), while the other variant has a glutamic acid to lysine substitution at residue 121, which is associated with the formation of hemoglobin O-Arab (HbO(Arab)). Subjects expressing this compound heterozygous HBB genotype may have severe sickling hemoglobinopathy with clinical manifestations similar to those of homozygous sickle cell anemia.


name: Idiopathic 46,XY Differences of Sex Development

description: Conditions affecting individuals whose karyotype is 46,XY that is characterized by atypical development of the internal or external sex structures, or the gonads, and in whom no genetic, environmental, or biochemical causation can be established.


name: Stage IIB Ampulla of Vater Cancer AJCC v7

description: Stage IIB includes: (T1, N1, M0); (T2, N1, M0); (T3, N1, M0).  T1: Tumor limited to ampulla of Vater or sphincter of Oddi.  T2: Tumor invades the duodenal wall.  T3: Tumor invades the pancreas.  N1: Regional lymph node metastasis.  M0: No distant metastasis. (from AJCC 7th Ed.)


name: Mediastinal Germ Cell Tumor N3 TNM Finding

description: Mediastinal germ cell tumor with metastasis in scalene and/or supraclavicular lymph nodes. (WHO Classification of Tumors of the Lung, Pleura, Thymus and Heart, 2015)


Cervical Cancer cN0 TNM Finding v7

description: Cervical cancer with no regional lymph node metastasis. (from AJCC 7th Ed.)


name: Type 1 Diabetes Mellitus with Mild Nonproliferative Diabetic Retinopathy with Macular Edema, Right Eye

description: Evidence of type 1 diabetes mellitus with mild nonproliferative diabetic retinopathy with macular edema in the right eye.


Islet Glucagon Cell Hyperplasia

description: Hyperplasia of the alpha cells of the pancreas.


name: Grade 3 Cardiac Troponin T Increased, CTCAE

description: Levels consistent with myocardial infarction as defined by the manufacturer


Malignant neoplasm of urethra local

description: A urethral carcinoma that has spread from its original site of growth to nearby tissues or lymph nodes.


name: Unresectable Pancreatic Neuroendocrine Carcinoma

description: Pancreatic neuroendocrine carcinoma that is not amenable to surgical resection.


Vulvar Cancer pM1 TNM Finding v8

description: Vulvar cancer with distant metastasis (including pelvic lymph node metastasis). (from AJCC 8th Ed.)


Mucosal Melanoma of the Urinary System

description: A malignant melanocytic neoplasm that arises from a mucosal site of the urinary system.


Exogenous Obesity

description: Obesity caused by caloric intake greater than caloric expenditures.


Biventricular congestive heart failure

description: Heart failure due to dysfunction of both the left and right ventricles.


name: Recurrent Extracranial Malignant Solid Neoplasm

description: The reemergence of an extracranial malignant solid neoplasm after a period of remission.


Immunotherapy-Related

description: An observation that a situation is related to immunotherapy received.


Proctitis, CTCAE

description: A disorder characterized by inflammation of the rectum.


Incorrect Patient Position

description: An artifact resulting from the incorrect positioning of the patient.


name: Aleukemic Acute Lymphoblastic Leukemia Cutis

description: Aleukemic acute lymphoblastic leukemia that manifests with cutaneous involvement.


name: Drug Use Complicating Pregnancy, Second Trimester

description: Evidence of drug use complicating pregnancy in the second trimester.


name: Ovarian Cancer and Primary Peritoneal Carcinoma TNM Finding v7

description: A finding about one or more characteristics of ovarian cancer or primary peritoneal carcinoma, following the rules of the TNM AJCC v7 classification system.  Ovarian cancer and primary peritoneal carcinoma are surgically/pathologically staged malignancies. (from AJCC 7th Ed.)


name: Other Specified Diabetes Mellitus with Proliferative Diabetic Retinopathy without Macular Edema, Unspecified Eye

description: Evidence of other specified diabetes mellitus with proliferative diabetic retinopathy without macular edema, unspecified eye not specified elsewhere.


name: Carcinoma of the Lacrimal Gland Pathologic Regional Lymph Nodes TNM Finding v7

description: A pathologic finding about one or more characteristics of carcinoma of the lacrimal gland, following the rules of the TNM AJCC v7 classification system as they pertain to staging of regional lymph nodes.


CDKN2A Gene Mutation Negative

description: A genetic finding indicating that CDKN2A gene mutations have not been detected in a sample.


Grade 3 Cognitive Disturbance, CTCAE

description: Severe cognitive disability; significant impairment of work/school/life performance


HPV16 Infection

description: An infection caused by human papillomavirus 16. HPV16 infection is associated with a risk for cervical cancer.


Grade 5 Neonatal Rash, AE

description: A rash adverse event in a newborn which results in death.


Hemangioma of conjunctiva

description: A hemangioma that arises from the conjunctiva.


Tumor Marker Response

description: An evaluation of the tumor marker response of the disease to the therapy.


name: Carcinoma of the Conjunctiva pT4a TNM Finding v7

description: Carcinoma of the conjunctiva with tumor invading the orbital soft tissues, without bone invasion. (from AJCC 7th Ed.)


Failure After First Treatment

description: A lack of response to the first cycle of therapy.


name: Neonatal Spontaneous Intestinal Perforation, AE

description: An adverse event in a newborn characterized by a perforation in the gastrointestinal tract of a newborn with no demonstrable cause.


name: Fallopian Tube Cancer pT3 TNM Finding v7

description: Fallopian tube cancer with tumor involving one or both fallopian tubes, with peritoneal implants outside the pelvis. (from AJCC 7th Ed.)


name: Type 1 Diabetes Mellitus with Proliferative Diabetic Retinopathy with Combined Traction Retinal Detachment and Rhegmatogenous Retinal Detachment, Right Eye

description: Evidence of type 1 diabetes mellitus with proliferative diabetic retinopathy with combined traction retinal detachment and rhegmatogenous retinal detachment in the right eye.


name: Grade 2 Vein NOS Intra-Operative Injury, CTCAE


Stress

description: The negative mental, emotional, and physical reactions that occur when environmental stressors are perceived as exceeding the individual's adaptive capacities.


name: Grade 4 Intraoperative Neurological Injury, CTCAE

description: Life-threatening consequences; urgent intervention indicated


Increased Drug Level

description: A laboratory test result demonstrating an increased concentration of a specific drug.


name: Esophageal Varices Hemorrhage, CTCAE 5.0

description: A disorder characterized by bleeding from esophageal varices.


name: Bipolar Disorder, Current Episode Manic without Psychotic Features, Severe

description: Evidence of bipolar disorder that is current episode manic without psychotic features that is severe.


Grade 1 Confusion, CTCAE

description: Mild disorientation


name: Thymic Tumor Pathologic Regional Lymph Nodes TNM Finding v8

description: A pathologic finding about one or more characteristics of a thymic tumor, following the rules of the TNM AJCC v8 classification system as they pertain to staging of regional lymph nodes.


Exertional Fatigue

description: Prolonged, extreme exhaustion after physical or mental effort or stress.


Surgical Complication

description: A disease or disorder that occurs during, soon after or as a result of a surgical procedure.


Grade 1 Feminization Acquired, CTCAE

description: Mild symptoms; intervention not indicated


Refractory Gallbladder Carcinoma

description: Gallbladder carcinoma that is resistant to treatment.


name: Gastric Cancer Pathologic Regional Lymph Nodes TNM Finding v7

description: A pathologic finding about one or more characteristics of gastric cancer, following the rules of the TNM AJCC v7 classification system as they pertain to staging of regional lymph nodes.


name: Major Salivary Gland Cancer pN2b TNM Finding v6 and v7

description: Major salivary gland cancer with metastasis in multiple ipsilateral lymph nodes, none more than 6 cm in greatest dimension. (from AJCC 6th and 7th Eds.)


Ileal Fistula

description: An abnormal communication between the ileum and another organ or cavity.


Vulvar Non-Neoplastic Disorder

description: A non-neoplastic disorder that affects the vulva. Representative examples include infection and fibroepithelial polyp.


name: Colorectal Cancer pM1 TNM Finding v6 and v7

description: Colorectal cancer with distant metastasis. (from AJCC 6th and 7th Eds.)


name: Exocrine Pancreatic Cancer pTis TNM Finding v6

description: Exocrine pancreatic cancer with a finding of carcinoma in situ, also known as grade III pancreatic intraepithelial neoplasia (PanIn III). (from AJCC 6th Ed.)


Recurrent Laryngeal Nerve Palsy, CTCAE

description: A disorder characterized by paralysis of the recurrent laryngeal nerve.


name: Grade 4 Artery Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


Vaginal Cancer cM0 TNM Finding v7

description: Vaginal cancer without evidence of distant metastasis. (from AJCC 7th Ed.)


External hydrocephalus

description: Abnormal increase of cerebrospinal fluid in the subdural space of the brain.


PSA Level Greater than 2.5

description: A blood concentration of prostate specific antigen greater than 2.5 ng/mL.


name: Grade 2 Pharynx Mucositis or Stomatitis by Functional or Symptomatic Classification, CTCAE


Grade 3 Gastric Fistula, CTCAE

description: Invasive intervention indicated


description: A Hodgkin lymphoma that develops in patients who are immunosuppressed with methotrexate.


name: Advanced Extrapulmonary Neuroendocrine Carcinoma

description: Extrapulmonary neuroendocrine carcinoma that has spread extensively to other anatomic sites or is no longer responding to treatment.


Adult Diffuse Mixed Cell Lymphoma

description: A B-or T-cell non-Hodgkin lymphoma composed of a mixed-sized lymphocytic population occurring in adults.


name: Stomach Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


name: Esophageal Large Cell Neuroendocrine Carcinoma

description: An aggressive, high-grade and poorly differentiated carcinoma with neuroendocrine differentiation that arises from the esophagus.  It is characterized by the presence of malignant large cells.


description: Evidence of bipolar disorder, current episode manic without psychotic features.


Retroperitoneal Hemorrhage

description: Bleeding originating in the retroperitoneal area.


Indeterminate Tumor Regression

description: A response that the tumor regression is indeterminate.


name: Serum CA19-9 Equal or Less than 180 Units/ml

description: A laboratory test result indicating the presence of a CA19-9 level in the serum which is equal or less than 180 units per ml.


Grade 3 Tendon Reflex Decreased, CTCAE

description: Absence of all reflexes


Grade 2 Hypotension, CTCAE

description: Non-urgent medical intervention indicated


Grade 1 Edema Limbs, CTCAE

description: 5-10% inter-limb discrepancy in volume or circumference at point of greatest visible difference; swelling or obscuration of anatomic architecture on close inspection


Flu Like Symptoms, CTCAE

description: A disorder characterized by a group of symptoms similar to those observed in patients with the flu. It includes fever, chills, body aches, malaise, loss of appetite and dry cough.


Matted Tumor Mass Present

description: A finding indicating that two or more tumors have merged to create a single cancerous mass.


name: Subglottic Cancer Pathologic Primary Tumor TNM Finding v7

description: A pathologic finding about one or more characteristics of subglottic cancer, following the rules of the TNM AJCC v7 classification system as they pertain to staging of the primary tumor.


Centrilobular Opacity

description: A radiologic finding indicating the presence of radio-opaque areas in the central parts of lung lobules.


Recurrent Subsequent Malignant Neoplasm

description: The reemergence of a malignant neoplasm other than the original one, after a period of remission.


name: Carcinoma of the Eyelid pT4 TNM Finding v7

description: Unresectable carcinoma of the eyelid due to extensive invasion of ocular, orbital, and craniofacial structures, or brain. (from AJCC 7th Ed.)


name: Grade 4 Neuroendocrine ADH Secretion Abnormality, CTCAE


name: Pauciarticular Juvenile Rheumatoid Arthritis, Right Hand

description: Evidence of pauciarticular juvenile rheumatoid arthritis in the right hand.


name: Melanoma of the Uvea Clinical Distant Metastasis TNM Finding v7

description: A clinical finding about one or more characteristics of melanoma of the uvea, following the rules of the TNM AJCC v7 classification system as they pertain to distant metastases.


name: Stage IVA Esophageal Squamous Cell Carcinoma


name: Visuospatial Deficit and Spatial Neglect following Cerebral Infarction

description: Evidence of visuospatial deficit and spatial neglect following cerebral infarction.


name: Bladder Cancer pM1 TNM Finding v6 and v7

description: Bladder cancer with distant metastasis. (from AJCC 6th and 7th Eds.)


Prostate Cancer cTX TNM Finding v7

description: Primary tumor cannot be assessed. (from AJCC 7th Ed.)


Grade 1 Obstruction Gastric, CTCAE

description: Asymptomatic; clinical or diagnostic observations only; intervention not indicated


name: Carcinoma of the Eyelid Clinical TNM Finding v7

description: A clinical finding about one or more characteristics of carcinoma of the eyelid, following the rules of the TNM AJCC v7 classification system.  Staging of eyelid carcinoma begins with a comprehensive ophthalmic, orbital, and periorbital clinical examination.  This approach includes a slit lamp or equivalent biomicroscopy evaluation, neuro-ophthalmic examination for evidence of perineural invasion, and regional assessment of the head and neck including lymphatic drainage basins. (from AJCC 7th Ed.)


Maxillary Sinus Cancer TNM Finding v7

description: A finding about one or more characteristics of maxillary sinus cancer, following the rules of the TNM AJCC v7 classification system.


Muscle Weakness Left-Sided, CTCAE

description: A disorder characterized by a reduction in the strength of the muscles on the left side of the body.


name: Grade 5 Catheter-Related Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


Eye Melanocytoma

description: A benign neoplastic melanocytic proliferation affecting the optic disk and optic nerve or the uvea.


name: Breast Cancer Pathologic Primary Tumor TNM Finding v6

description: A pathologic finding about one or more characteristics of breast cancer, following the rules of the TNM AJCC v6 classification system as they pertain to staging of the primary tumor. TNM pathologic primary tumor findings are based on clinical findings supplemented by histopathologic examination of one or more tissue specimens acquired during surgery.


Cutaneous Melanoma cM1b TNM Finding v7

description: Cutaneous melanoma with metastases to lung associated with normal serum lactate dehydrogenase (LDH). (from AJCC 7th Ed.)


name: Grade 3 Intraoperative Urinary Injury, CTCAE

description: Complete resection or reconstruction of injured organ/structure indicated; limiting self care ADL


tubular adenoma of gallbladder

description: An adenoma that arises from the gallbladder.  It is characterized by the presence of a tubular growth pattern.


End Organ Damage from Diabetes

description: Irreparable damage to multiple organs/systems which is the result of chronic complications of diabetes.  The affected organs/systems include the cardiovascular system, kidneys, eyes, nervous system, joints and feet.


name: Grade 4 Dental and Teeth and Peridontal Pain, CTCAE


name: Grade 5 Neonatal Culture Negative Sepsis, AE

description: A culture negative neonatal sepsis adverse event in a newborn which results in death.


name: Human Papillomavirus-Related Cervical Carcinoma

description: A carcinoma that arises from the cervix and is caused by human papillomavirus infection.


Vaginal Cancer TNM Finding v8

description: A finding about one or more characteristics of vaginal cancer, following the rules of the TNM AJCC v8 classification system. This classification system applies to all carcinomas of the vagina. There is no AJCC staging system for mucosal melanoma of the vagina. (from AJCC 8th Ed.)


Stage IV Uterine Corpus Cancer AJCC v6

description: Stage IV includes: IVA: (T4, Any N, M0); IVB: (Any T, Any N, M1).  T4: Tumor invades bladder mucosa and/or bowel mucosa (bullous edema is not sufficient to classify a tumor as T4).  M1: Distant metastasis (includes metastasis to abdominal lymph nodes other than para-aortic, and/or inguinal lymph nodes: excludes metastasis to vagina, pelvic serosa, or adnexa). (AJCC 6th ed.)


Grade 4 Pharyngeal Mucositis, CTCAE

description: Life-threatening consequences; urgent intervention indicated


Grade 3 Sinus Tachycardia, CTCAE

description: Urgent medical intervention indicated


Urethral Cancer pN2 TNM Finding v7

description: Urethral cancer with metastasis in a singe lymph node more than 2 cm in greatest dimension or in multiple lymph nodes. (from AJCC 7th Ed.)


Oligometastatic Gastric Adenocarcinoma

description: Gastric adenocarcinoma that has metastasized to a limited number of sites.


Grade 3 Cystitis Noninfective, CTCAE

description: Gross hematuria; transfusion, IV medications, or hospitalization indicated; elective invasive intervention indicated


name: Grade 3 Irritability in Children Less Than 3 Years of Age, CTCAE


Grade 3 Cushingoid, CTCAE

description: Severe symptoms, medical intervention or hospitalization indicated


Stage IB Vulvar Carcinoma AJCC v6

description: Stage IB includes: T1b, N0, M0.  T1ab Tumor confined to the vulva or vulva and perineum, 2cm or less in greatest dimension, and with stromal invasion greater than 1mm.  N0: No regional lymph node metastasis.  M0: No distant metastasis. (AJCC 6th ed.)


name: Appendix Neuroendocrine Tumor by AJCC v8 Stage

description: A term that refers to the staging of an appendiceal neuroendocrine tumor, following the rules of the TNM AJCC v8 classification system. This staging system applies to appendiceal NETs (carcinoid tumors) (NET G1 and G2, and rare well-differentiated G3). High-grade neuroendocrine carcinomas (NEC), goblet cell carcinoids, mixed adenocarcinomas, and adenocarcinomas of the appendix are not staged using this staging system. (from AJCC 8th Ed.)


Breast Neuroendocrine Tumor G1

description: A well-differentiated, low grade neuroendocrine neoplasm arising from the breast.


Grade 3 Cough, CTCAE

description: Severe symptoms; limiting self care ADL


name: Grade 1 Neonatal Respiratory Insufficiency, AE

description: An adverse event in a newborn characterized by clinical evidence of mildly increased respiratory distress (e.g. increased work of breathing) without significant deterioration in gas exchange (increase in partial pressure of carbon dioxide (pCO2) or decrease in oxygenation); no change in baseline functioning; no care changes required.


Partial DNA Methylation

description: An indication that 10-90% of the CpG islands in a gene or gene promoter have detectable methylation.


Continued Complete Response

description: The patient had achieved a complete response; received more therapy and continued in complete response.


Grade 4 Myocarditis, CTCAE

description: Life-threatening consequences; urgent intervention indicated (e.g., continuous IV therapy or mechanical hemodynamic support)


MGMT-Methylated Glioblastoma

description: A glioblastoma characterized by the presence of DNA methylation in the promoter region of the MGMT gene. It is associated with improved survival.


name: Atherosclerosis of Native Arteries of the Extremities with Gangrene, Left Leg

description: Evidence of atherosclerosis of native arteries of the extremities with gangrene in the left leg.


Chief Complaint is Present Daily

description: The chief complaint is noted to occur at least once per day.


Stage III Skin Cancer

description: Stage III includes: (T3, N0, M0); (T1, N1, M0); (T2, N1, M0); (T3, N1, M0).  T3: Tumor with invasion of maxilla, mandible, orbit, or temporal bone.  T1: Tumor 2 cm or less in greatest dimension with less than two high-risk features.  T2: Tumor size greater than 2 cm in greatest dimension or tumor of any size with two or more high-risk features.  N0: No regional lymph node metastasis.  N1: Metastasis in a single ipsilateral lymph node, 3 cm or less in greatest dimension.  M0: No clinical or radiographic evidence of distant metastasis.  (AJCC 7th Ed.)


Mental Retardation, X-linked 21/34

description: An X-linked recessive condition caused by mutation(s) in the IL1RAPL1 gene, encoding interleukin-1 receptor accessory protein-like 1. It is characterized by intellectual disability ranging from moderate mental retardation to high-functioning autism.


PSA Level Four to Ten

description: A blood concentration of prostate specific antigen between 4 ng/mL and 10 ng/mL.


name: Other Psychoactive Substance Dependence with Psychoactive Substance-Induced Psychotic Disorder with Hallucinations

description: Evidence of other psychoactive substance dependence with psychoactive substance-induced psychotic disorder with hallucinations not specified elsewhere.


name: Left Posterior Middle Transition Zone of Prostate

description: The region of the prostate that is located on the anatomical left side of the posterior portion of the middle division of the transition zone.


name: Endometrial Endometrioid Adenocarcinoma with a Poorly Differentiated Carcinomatous Component

description: A primary endometrioid adenocarcinoma of the endometrium characterized by the presence of a component with poorly differentiated carcinoma cells.


name: Grade 3 Glomerular Filtration Rate, CTCAE


Grade 2 Hypohidrosis, CTCAE

description: Symptomatic; limiting instrumental ADL


name: Diabetes Mellitus due to Underlying Condition with Severe Non-Proliferative Diabetic Retinopathy without Macular Edema, Right

description: Evidence of diabetes mellitus due to underlying condition with severe non-proliferative diabetic retinopathy without macular edema in the right.


Body Mass Index 39.0-39.9, Adult

description: Evidence of a body mass index of 39.0-39.9 in the adult.


Grade 5 Glucose Intolerance, CTCAE

description: Death


name: Unspecified Combined Systolic and Diastolic Congestive Heart Failure

description: Evidence of unspecified combined systolic and diastolic congestive heart failure.


name: Appendix Neuroendocrine Tumor pTX TNM Finding v8

description: Appendix neuroendocrine tumor in which the primary tumor cannot be assessed. (from AJCC 8th Ed.)


name: Thyroid Stimulating Hormone Increased, CTCAE

description: A disorder characterized by an increase in thyroid stimulating hormone.


name: Renal Pelvis and Ureter Cancer pN0 TNM Finding v8

description: Renal pelvis and ureter cancer with no regional lymph node metastasis. (from AJCC 8th Ed.)


name: Grade 4 Salivary Duct Inflammation, CTCAE

description: Life-threatening consequences; urgent intervention indicated


name: Other Specified Diabetes Mellitus with Stable Proliferative Diabetic Retinopathy, Left Eye

description: Evidence of other specified diabetes mellitus with stable proliferative diabetic retinopathy in the left eye not specified elsewhere.


Stage I Gallbladder Cancer AJCC v6

description: Stage I includes: IA: (T1, N0, M0); IB: (T2, N0, M0). T1: Tumor invades lamina propria or muscle layer.  T1a: Tumor invades lamina propria.  T1b: Tumor invades muscle layer.  N0: No regional metastasis.  M0: No distant metastasis. (AJCC 6th ed.)


Stage IV Childhood Large Cell Lymphoma

description: Stage IV: Disseminated (multifocal) involvement of one or more extralymphatic sites with or without associated lymph node involvement or isolated extralymphatic organ involvement with distant (nonregional) nodal involvement. (from PDQ)


Merkel cell carcinoma of nose

description: Evidence of Merkel cell carcinoma of nose.


name: Rheumatoid Vasculitis with Rheumatoid Arthritis of Left Ankle and Foot

description: Evidence of rheumatoid vasculitis with rheumatoid arthritis of left ankle and foot.


name: Direct Infection of Unspecified Shoulder in Infectious and Parasitic Diseases Classified Elsewhere

description: Evidence of direct infection of unspecified shoulder in infectious and parasitic diseases classified elsewhere.


name: Other Classic Hodgkin Lymphoma, Unspecified Site

description: Evidence of other classic Hodgkin lymphoma in an unspecified site not specified elsewhere.


name: Hemiplegia following Non-Traumatic Intracerebral Hemorrhage Affecting Right Non-Dominant Side

description: Evidence of hemiplegia following non-traumatic intracerebral hemorrhage affecting right non-dominant side.


name: Recurrent Fallopian Tube Transitional Cell Carcinoma

description: The reemergence of fallopian tube transitional cell carcinoma after a period of remission.


name: Adverse Event Associated with the Vascular System


name: Neonatal Respiratory Distress Syndrome, AE

description: An adverse event in a newborn characterized by progressive alveolar atelectasis from birth due to an abnormality of synthesis, function or metabolism of surfactant, characterized by respiratory failure and an abnormal chest radiograph showing diffuse reticulogranular densities and air bronchograms.


name: Conjunctival Melanoma pTX TNM Finding v8

description: Conjunctival melanoma in which the primary tumor cannot be assessed. (from AJCC 8th Ed.)


name: Grade 1 Flashing Lights and Floaters in Vision, CTCAE


Grade 2 Trochlear Nerve Disorder, CTCAE

description: Moderate symptoms; limiting instrumental ADL


name: Duodenum and Ampulla of Vater Neuroendocrine Tumor cM1a TNM Finding v8

description: Duodenum and ampulla of Vater neuroendocrine tumor with metastasis confined to liver. (from AJCC 8th Ed.)


Grade 2 Weight Loss, CTCAE

description: 10-<20% from baseline; nutritional support indicated


description: Evidence of alcohol dependence with alcohol-induced sexual dysfunction.


name: Stage IIIB Cervical Cancer AJCC v6 and v7

description: Stage IIIB includes: (T3b, Any N, M0); (T1-3, N1, M0).  T3: Tumor extends to pelvic wall and/or involves lower third of vagina, and/or causes hydronephrosis or non-functioning kidney. T3b: Tumor extends to pelvic wall and/or causes hydronephrosis or non-functioning kidney. N1: Regional lymph node metastasis. M0: No distant metastasis. (AJCC 6th and 7th eds.)


Breast Cancer pT2 TNM Finding v8

description: Breast cancer with tumor size more than 20 mm, but not more than 50 mm in greatest dimension. (from AJCC 8th Ed.)


Enteropathic Arthropathies, Left Knee

description: Evidence of enteropathic arthropathies in the left knee.


Malignant melanoma, regressing

description: A skin lesion characterized by the disappearance of the melanoma cells from the primary melanoma site. The disappearance of the malignant cells is associated with fibroplasia of the papillary dermis. According to some authors, complete regression of the primary melanoma may occur in 4-8% of patients.


name: Grade 5 Supraventricular Arrhythmia NOS, CTCAE


Foreign body embolism

description: Occlusion of a lumen by a foreign object.


Grade 3 Pleuritic Pain, CTCAE

description: Severe pain; limiting self care ADL


Lentigo simplex

description: The most common form of the skin disorder lentigo, characterized by a single or multiple benign, pigmented macules of unknown etiology that are present at birth or develop in early childhood.


Gastric Cancer Clinical TNM Finding v6

description: A clinical finding about one or more characteristics of gastric cancer, following the rules of the TNM AJCC v6 classification system.


Increased Concomitant Drug Half Life

description: Increased period of time required for the concentration or amount of a concomitant drug in the body to be reduced to exactly one-half of a given concentration or amount.


Other Non-Follicular Lymphoma, Spleen

description: Evidence of other non-follicular lymphoma in the spleen not specified elsewhere.


name: Grade 4 Breast Intra-Operative Injury, CTCAE


name: Hodgkin's disease nodular sclerosis stage II subdiaphragmatic


Transaminitis

description: Abnormally high levels of alanine transaminase (ALT) and/or aspartate transaminase (AST) in the blood.


name: Malignant Neoplasm of Connective and Soft Tissue of Unspecified Upper Limb, Including Shoulder

description: Evidence of a malignant neoplasm of connective and soft tissue of unspecified upper limb including the shoulder.


name: Grade 3 Vulva Infection with Unknown Absolute Neutrophil Count, CTCAE


name: Other Diabetes with Diabetic Macular Edema, Resolved following Treatment, Bilateral

description: Evidence of other diabetes with diabetic macular edema, which is resolved following treatment that is bilateral not specified elsewhere.


name: Stage 0 Cutaneous Melanoma AJCC v6 and v7

description: Stage 0 includes: Tis, N0, M0.  Tis: Melanoma in situ.  N0: No regional lymph node metastases.  M0: No detectable evidence of distant metastases. (from AJCC 6th and 7th Eds.)


Death by Overdose

description: A death that is attributed to an excessive amount of a substance.


Gallbladder Cancer pT0 TNM Finding v8

description: Gallbladder cancer with no evidence of primary tumor. (from AJCC 8th Ed.)


Calcifying Odontogenic Cyst

description: A simple odontogenic cyst lined by ameloblastoma-like epithelium, which contains focal accumulations of ghost cells. (WHO 2017)


name: Diffuse Follicular Center Lymphoma, Extranodal and Solid Organ Sites

description: Evidence of diffuse follicular center lymphoma, extranodal and solid organ sites.


Testicular Pain, CTCAE 5.0

description: A disorder characterized by a sensation of marked discomfort in the testis.


name: Grade 1 Peripheral Motor Nerve NOS Intra-Operative Injury, CTCAE


Refractory Myeloid Neoplasm

description: A myeloid neoplasm that does not respond to treatment.


Stage IV Bladder Cancer AJCC v6

description: Stage IV includes the following: T4b, N0, M0; Any T, N1, M0; Any T, N2 M0; Any T, N3 M0; Any T, Any N, M1.  T4b: Tumor invades the pelvic wall, abdominal wall.  N1: Metastasis in a single lymph node, 2 cm or less in greatest dimension.  N2: Metastasis in a single lymph node, more than 2 cm but not more than 5 cm in greatest dimension; or multiple lymph nodes, none more than 5 cm in greatest dimension.  N3: Metastasis in a lymph node more than 5 cm in greatest dimension.  M1: Distant metastasis.  (AJCC 6th Ed.)


name: Cerebral Infarction To Thrombosis of Bilateral Posterior Cerebral Arteries

description: Evidence of cerebral infarction to thrombosis of bilateral posterior cerebral arteries.


name: Grade 4 Paranasal Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


Pathologic Primary Tumor TNM Finding

description: A pathologic finding about one or more characteristics of a specific cancer, following the rules of the TNM classification system as they pertain to evaluating the primary tumor.


Intestinal nematode infection

description: An infection in the gastrointestinal tract by a nematode.


name: Grade 1 Other Hemorrhage and Bleeding, CTCAE


Stage IIA Anal Cancer AJCC v8

description: Stage IIA includes: T2, N0, M0. T2: Tumor larger than 2 cm but equal to or smaller than 5 cm. N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 8th ed.)


Sickness

description: A state of ill health, bodily malfunction, or discomfort.


Treatment related secondary malignancy

description: The development of a malignant neoplasm in response to medical or surgical treatment, induced by the treatment itself.


Grade 2 Vaginal Fistula, CTCAE

description: Symptomatic, invasive intervention not indicated


Grade 1 Productive Cough, CTCAE

description: Occasional/minimal production of sputum with cough


name: Anal Extramucosal (Perianal) Adenocarcinoma

description: An anal adenocarcinoma arising from the lining of an anorectal fistulous tract or the anal glands.  The overlying anal mucosa does not show evidence of neoplastic changes.  It usually presents as a submucosal tumor.


Grade 1 Oral Cavity Fistula, CTCAE

description: Asymptomatic


name: flaccid hemiplegia affecting right dominant side

description: Evidence of flaccid hemiplegia affecting the right dominant side.


name: Follicular Lymphoma Grade IIIb, Lymph Nodes of Head, Face, and Neck

description: Evidence of follicular lymphoma grade IIIb in the lymph nodes of head in the face in the and neck.


name: Glottic Cancer Pathologic Distant Metastasis TNM Finding v7

description: A pathologic finding about one or more characteristics of glottic cancer, following the rules of the TNM AJCC v7 classification system as they pertain to distant metastases.  There is no pathologic M0 for glottic cancer.


name: Grade 3 Kidney Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


name: Grade 3 Trigeminal Nerve Disorder, CTCAE

description: Severe symptoms; limiting self care ADL


Trichogerminoma

description: A rare subtype of trichoblastoma characterized by the presence of lobules of basaloid cells. The lobules are separated by fibrous stroma. It is associated with the expression of recurrent FOXK1/GRHL and GPS2/GRHL gene fusions.


name: Childhood Acute Myeloid Leukemia with t(9;11)(p21.3;q23.3); MLLT3-KMT2A

description: An acute myeloid leukemia with t(9;11)(p21.3;q23.3); MLLT3-KMT2A occurring in children.


name: Diffuse Follicular Center Lymphoma, Intra-abdominal Lymph Nodes

description: Evidence of diffuse follicular center lymphoma, intra-abdominal lymph nodes.


name: Stage IV Childhood Hodgkin Lymphoma by Toronto Guidelines v2

description: Diffuse or disseminated (multifocal) involvement of one or more extra-lymphatic organs with or without associated lymph node involvement or isolated (non-contiguous) extra-lymphatic organ involvement in the absence of adjacent regional lymph node involvement, but in conjunction with disease in distant site(s) or any involvement of liver, bone marrow, lungs (except by direct extension from another site) or CSF. This definition applies to both tiers (tier 1 and 2). (Childhood cancer staging for population registries according to the Toronto Childhood Cancer Stage Guidelines - Version 2. Cancer Council Queensland and Cancer Australia: Brisbane, Australia; 2021.)


Locally Advanced Neuroendocrine Tumor

description: A neuroendocrine tumor that has spread from its original site of growth to nearby tissues or lymph nodes.


name: Grade 5 Penis Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


name: Hemiplegia following Non-Traumatic Subarachnoid Hemorrhage Affecting Unspecified Side

description: Evidence of hemiplegia following non-traumatic subarachnoid hemorrhage affecting unspecified side.


opioid abuse with withdrawal

description: Evidence of opioid abuse with withdrawal.


name: Sinus Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


Tracheal Mucositis

description: An inflammatory process affecting the mucous membrane of the trachea.


name: Lugano Classification Stage II Bulky Adult Hodgkin Lymphoma AJCC v8

description: Stage II Bulky: Stage II with disease bulk. (from AJCC 8th Ed.)


Orbital Contusion

description: Bruising of the skin and soft tissue surrounding the eye.


name: Distal Bile Duct Cancer pT2 TNM Finding v7

description: Distal bile duct cancer with tumor invading beyond the wall of the bile duct. (from AJCC 7th Ed.)


name: Acute Myeloid Leukemia with a Variant MECOM Rearrangement

description: A term referring to acute myeloid leukemias with rearrangement of the MECOM gene with various genes other than the GATA2 gene.


Dialysis Access Failure

description: Failure to perform hemodialysis due to blockage of the artery-vein grafts which provide the requisite vascular access.


name: Hemiplegia following Non-Traumatic Subarachnoid Hemorrhage Affecting Right Non-Dominant Side

description: Evidence of hemiplegia following non-traumatic subarachnoid hemorrhage affecting right non-dominant side.


Cystic Periventricular Leukomalacia

description: Necrosis and softening of the white matter around the ventricles in the brain associated with cystic changes.


Abnormal Flexure

description: A flexure that is deviating from the norm or outwith the bounds of what is considered normal.


Hamartoma of Mature Cardiac Myocytes

description: A non-malignant, focal growth in the heart, composed of unencapsulated nodules of enlarged, hypertrophic, mature cardiac myocytes with a variable amount of collagen and fat.


Vaginal Cancer pTis TNM Finding v7

description: Vaginal cancer with a finding of carcinoma in situ. (from AJCC 7th Ed.)


Prosoposchisis

description: A congenital anatomic defect characterised by a facial cleft that extends from the mouth to the orbit of the eye.


name: Grade 4 Colon or Cecum or Appendix Necrosis, CTCAE


name: Grade 2 Genitourinary Stoma Stricture or Stenosis, CTCAE


name: Advanced Malignant Female Reproductive System Neoplasm

description: A malignant female reproductive system neoplasm that has spread extensively from its original site of growth to other anatomic sites or is no longer responding to treatment.


Disorder of soft tissue

description: A non-neoplastic or neoplastic disorder that affects the soft tissue.


name: Grade 2 Skin and Subcutaneous Tissue Disorders - Other, Specify, CTCAE

description: Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL


name: Small Intestine Cancer cM1 TNM Finding v7

description: Small intestine cancer with distant metastasis. (from AJCC 7th Ed.)


ERBB2 Gene Amplification Negative

description: An indication that amplification of the ERBB2 gene was not detected in a sample.


Anatomic Artifact

description: An artifact resulting from the specific anatomy of the patient.


name: Grade 5 Intraoperative Hepatobiliary Injury, CTCAE

description: Death


name: Nose Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


Sporadic Retinoblastoma

description: A retinoblastoma that occurs in a patient without a family history of the disease.


name: Grade 3 Oral Cavity or Gum Infection with Unknown Absolute Neutrophil Count, CTCAE


Grade 1 Anorexia, CTCAE

description: Loss of appetite without alteration in eating habits


hypertensive retinopathy of left eye

description: Evidence of hypertensive retinopathy in the left eye.


Intraoperative Splenic Injury, CTCAE

description: A finding of damage to the spleen during a surgical procedure.


name: Malignant Non-Hodgkin's Lymphoma, Diffuse, Lymphocytic, Poorly Differentiated


Grade 5 Spasticity, CTCAE

description: Death


name: Intra-Operative Injury by Anatomic Descriptor, CTCAE


name: alk-positive anaplastic large cell lymphoma in extranodal and solid organ sites

description: Evidence of anaplastic large cell lymphoma that is ALK-Positive in the extranodal and solid organ sites.


Recurrent Acute Leukemia

description: The reemergence of acute leukemia after a period of remission.


Locally Advanced Angiosarcoma

description: An angiosarcoma that has spread from its original site of growth to nearby tissues or lymph nodes.


name: Mucosal Melanoma of the Head and Neck Pathologic Distant Metastasis TNM Finding v7

description: A pathologic finding about one or more characteristics of mucosal melanoma of the head and neck, following the rules of the TNM AJCC v7 classification system as they pertain to distant metastases.  There is no pathologic M0 for mucosal melanoma of the head and neck.


Normal Blood Test Result

description: A laboratory test result indicating the results of the blood test are within normal parameters for the age and population.


description: Evidence of hallucinogen dependence with intoxication with delirium.


name: Grade 2 Meninges Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


name: Intracystic papillary neoplasm with low grade intraepithelial neoplasia

description: An intracholecystic papillary neoplasm that arises from the epithelium of the gallbladder. It is characterized by the presence of mild epithelial atypia.


name: Grade 5 Visceral Arterial Ischemia, CTCAE

description: Death


name: Grade 2 Periventricular Leukomalacia, AE

description: An adverse event in a newborn characterized by transient periventricular echodensities evolving in to small localized fronto-parietal cysts or persistent diffuse echodensities.


name: Rheumatoid Arthritis of Right Ankle and Foot with Involvement of Organs and Systems

description: Evidence of rheumatoid arthritis of right ankle and foot with involvement of organs and systems.


name: Carcinoma in situ of other and unspecified female genital organs

description: Evidence of carcinoma in situ of other and unspecified female genital organs.


FGFR1 Gene Mutation Negative

description: A genetic finding indicating that FGFR1 gene mutations have not been detected in a sample.


name: Stage I Childhood Malignant Kidney Neoplasm Excluding Renal Cell Carcinoma by Toronto Guidelines v2, Children's Oncology Group (COG) Protocol

description: Tumor is limited to the kidney and completely excised. Renal capsule intact, not penetrated by tumor. No tumor invasion of veins or lymphatics of renal sinus. No nodal or hematogenous metastases. No prior biopsy. Negative margins. (Childhood cancer staging for population registries according to the Toronto Childhood Cancer Stage Guidelines - Version 2. Cancer Council Queensland and Cancer Australia: Brisbane, Australia; 2021.)


Grade 5 Vasculitis, CTCAE

description: Death


name: Grade 4 Liver Infection with Unknown Absolute Neutrophil Count, CTCAE


Recurrent Myeloid Neoplasm

description: The reemergence of a myeloid neoplasm after a period of remission.


Pansclerotic Morphea

description: A rare, aggressive form of morphea characterized by sclerosis of the dermis, fascia, and muscle over large parts of the body, resulting in contractures and immobility.


Endocrine Therapy-Induced Alopecia

description: Alopecia caused by treatment with endocrine therapy agents.


Grade 5 Myelodysplastic Syndrome, CTCAE

description: Death


Death NOS, CTCAE

description: Death that cannot be attributed to a CTCAE term associated with Grade 5.


Colorectal Cancer pM1a TNM Finding v7

description: Colorectal cancer with metastasis confined to one organ or site (e.g., liver, lung, ovary, nonregional node). (from AJCC 7th Ed.)


name: Transplant-Related Skin Squamous Cell Carcinoma

description: A squamous cell carcinoma that arises from the skin in a patient with a history of organ transplantation.


name: Grade 2 Fallopian Tube Intra-Operative Injury, CTCAE


name: Radiating Chest Pain Along Right Midclavicular Line

description: The location of the radiating chest pain is along the right midclavicular line.


name: Oropharyngeal (p16-Negative) Cancer cN2a TNM Finding v8

description: Oropharyngeal (p16-negative) cancer with metastasis in a single ipsilateral lymph node larger than 3 cm but not larger than 6 cm in greatest dimension and ENE(-). (from AJCC 8th Ed.)


name: Female Non-Neoplastic Reproductive System Disorder

description: A non-neoplastic disorder that affects the female reproductive system. Representative examples include endometriosis, pelvic inflammatory disease, and endometritis.


Neonatal Late-Onset Sepsis

description: An infectious disorder of newborn infants that is characterized by a systemic inflammatory response beyond 72 hours of life and is most commonly caused by bacteria.


Rheumatoid Bursitis, Left Elbow

description: Evidence of rheumatoid bursitis in the left elbow.


name: Grade 3 Cranial Nerve I Intra-Operative Injury, CTCAE


name: Pleural Malignant Mesothelioma pT1 TNM Finding v8

description: Pleural malignant mesothelioma with tumor limited to the ipsilateral parietal with or without involvement of visceral pleura, mediastinal pleura, and diaphragmatic pleura. (from AJCC 8th Ed.)


name: Appendix Neuroendocrine Tumor TNM Finding v8

description: A finding about one or more characteristics of an appendiceal neuroendocrine tumor, following the rules of the TNM AJCC v8 classification system. This classification system applies to appendiceal NETs (carcinoid tumors) (NET G1 and G2, and rare well-differentiated G3). It does not apply to high-grade neuroendocrine carcinomas (NEC), goblet cell carcinoids, mixed adenocarcinomas, and adenocarcinomas of the appendix. (from AJCC 8th Ed.)


Recurrent Pancreatic Cystadenocarcinoma

description: The reemergence of pancreatic cystadenocarcinoma after a period of remission.


lipoma of bone

description: A benign neoplasm which is composed of adipocytes and arises from the surface of the bone or the medullary cavity.


name: Head and Neck Cancer cN2b TNM Finding v8

description: Head and neck cancer with metastasis in multiple ipsilateral lymph nodes, none larger than 6 cm in greatest dimension and ENE(-). (from AJCC 8th Ed.)


name: central retinal artery occlusion of left eye

description: Evidence of central retinal artery occlusion in the left eye.


name: Rheumatoid Arthritis without Rheumatoid Factor, Left Knee

description: Evidence of rheumatoid arthritis without rheumatoid factor in the left knee.


Grade 5 Neonatal Convulsion, AE

description: An adverse event in a newborn characterized by death related to suspected seizures.


Extrapulmonary Neuroendocrine Carcinoma

description: A small or large cell neuroendocrine carcinoma that arises from an anatomic site other than the lung.


Prostate Myeloid Sarcoma

description: Myeloid sarcoma that affects the prostate gland.  It may present in association with or as a site of relapse of acute myeloid leukemia.  Cases of myeloid sarcoma of the prostate gland preceding acute myeloid leukemia have also been reported.


CDKN2A Negative

description: Indicates that expression of CDKN2A has not been detected in a sample.


name: Refractory Blastic Plasmacytoid Dendritic Cell Neoplasm

description: Blastic plasmacytoid dendritic cell neoplasm that is resistant to treatment.


name: Supraglottic Cancer Clinical Distant Metastasis TNM Finding v7

description: A clinical finding about one or more characteristics of supraglottic cancer, following the rules of the TNM AJCC v7 classification system as they pertain to distant metastases.


name: Grade 5 Otitis External Ear Non Infectious, CTCAE


Hot Flashes, CTCAE

description: A disorder characterized by an uncomfortable and temporary sensation of intense body warmth, flushing, sometimes accompanied by sweating upon cooling.


name: Pre-Existing Type 1 Diabetes Mellitus, in Pregnancy, First Trimester

description: Evidence of pre-existing type 1 diabetes mellitus in the in pregnancy in the first trimester.


name: Hypopharyngeal Cancer cN3 TNM Finding v8

description: Hypopharyngeal cancer with metastasis in a lymph node larger than 6 cm in greatest dimension and ENE(-); or metastasis in any node(s) and clinically overt ENE(+). (from AJCC 8th Ed.)


name: Dysphagia following Unspecified Cerebrovascular Disease

description: Evidence of dysphagia following unspecified cerebrovascular disease.


description: Evidence of hallucinogen abuse with hallucinogen-induced psychotic disorder with hallucinations.


Neonatal Epileptic Seizure, AE

description: An adverse event in a newborn characterized by an electroencephalogram (EEG) confirmed paroxysmal surge of electrical activity in the brain that may result in physical or behavioral changes.


name: Nasopharyngeal Cancer Pathologic Distant Metastasis TNM Finding v7

description: A pathologic finding about one or more characteristics of nasopharyngeal cancer, following the rules of the TNM AJCC v7 classification system as they pertain to distant metastases.  There is no pathologic M0 for nasopharyngeal cancer.


Non-Neoplastic Sternal Disorder

description: A non-neoplastic disorder that affects the sternum.


Grade 3 Dizziness, CTCAE

description: Severe unsteadiness or sensation of movement; limiting self care ADL


name: Grade 2 Ureter Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


Interim Response

description: An evaluation prior to the completion of therapy that the individual is responding to therapy.


Locally Advanced Gastric Carcinoma

description: A gastric carcinoma that has spread from its original site of growth to nearby tissues or lymph nodes.


Vulvar Melanocytic Neoplasm

description: A neoplasm that originates from melanocytes and arises from the vulva. This category includes congenital and acquired melanocytic nevus, blue nevus, dysplastic melanocytic nevus, atypical melanocytic nevus of genital type, and melanoma.


Grade 1 Chest Pain - Cardiac, CTCAE

description: Mild pain


name: Prolonged Intubation After Pulmonary Resection, CTCAE


name: Grade 1 Portal Vein Intra-Operative Injury, CTCAE


name: Appendiceal Carcinoid Pathologic TNM Finding v7

description: A pathologic finding about one or more characteristics of appendiceal carcinoid, following the rules of the TNM AJCC v7 classification system.  Appendiceal carcinoids are usually staged after laparoscopic or open surgical exploration of the abdomen (often for appendicitis) and pathologic examination of the resected specimen.  (from AJCC 7th Ed.)


Recurrent Adult Hodgkin Lymphoma

description: The reemergence of Hodgkin lymphoma in adulthood after a period of remission.


Classical Poroma

description: A poroma characterized by the presence of cords and aggregates of neoplastic cells in the superficial dermis in connection with the epidermis.


Spermatic Cord Anastomotic Leak, CTCAE

description: A finding of leakage due to breakdown of a spermatic cord anastomosis (surgical connection of two separate anatomic structures).


Body Mass Index 60.0-69.9, Adult

description: Evidence of a body mass index of 60.0-69.9 in the adult.


name: Nasal Cavity and Ethmoid Sinus Cancer cM0 TNM Finding v7

description: Nasal cavity and ethmoid sinus cancer without evidence of distant metastasis. (from AJCC 7th Ed.)


name: Duodenum/Ampulla/Jejunum/Ileum Neuroendocrine Tumor pT3 TNM Finding v7

description: Duodenum/ampulla/jejunum/ileum neuroendocrine tumor invading through the muscularis propria into subserosal tissue without penetration of overlying serosa (jejunal or ileal tumors) or invading pancreas or retroperitoneum (ampullary or duodenal tumors) or into non-peritonealized tissues. (from AJCC 7th Ed.)


Environment-Related Malignant Neoplasm

description: Cancers caused by exposure to carcinogens in the general environment


Moist Desquamation

description: A skin reaction characterized by sloughing of the epidermis and serous exudate.


NTRK Family Fusion Gene Negative

description: An indication that fusions involving NTRK family genes have not been detected in a sample.


Incidental Gallbladder Carcinoma

description: Gallbladder carcinoma that is discovered incidental to gallbladder surgery for another indication.


Grade 5 Leukoencephalopathy, CTCAE

description: Death


name: Diabetes Mellitus due to Underlying Condition with Moderate Non-Proliferative Diabetic Retinopathy with Macular Edema, Bilateral

description: Evidence of diabetes mellitus due to underlying condition with moderate non-proliferative diabetic retinopathy with macular edema that is bilateral.


Penile Pain, CTCAE 5.0

description: A disorder characterized by a sensation of marked discomfort in the penis.


name: Grade 3 Cecum or Appendix Hemorrhage, CTCAE


POLE Gene Mutation Negative

description: A genetic finding indicating that POLE gene mutations have not been detected in a sample.


name: Sciatic Nerve Intra-Operative Injury, CTCAE


name: Soft Tissue Sarcoma of the Head and Neck pT4 TNM Finding v8

description: Soft tissue sarcoma of the head and neck with tumor invading adjoining structures. (from AJCC 8th Ed.)


name: Drug or Chemical Induced Diabetes Mellitus with Diabetic Macular Edema, Resolved following Treatment, Unspecified Eye

description: Evidence of drug or chemical induced diabetes mellitus with diabetic macular edema, which is resolved following treatment in an unspecified eye.


Bladder Cancer pT1 TNM Finding v8

description: Bladder cancer with tumor invading lamina propria (subepithelial connective tissue). (from AJCC 8th Ed.)


Grade 1 Tumor Pain, CTCAE

description: Mild pain


Advanced Esophageal Carcinoma

description: Esophageal carcinoma that has spread extensively to other anatomic sites or is no longer responding to treatment.


Grade 2 Gastritis, CTCAE

description: Symptomatic; altered GI function; medical intervention indicated


Stage II Prostate Cancer AJCC v8

description: Stage II includes: IIA: (cT1a-c, cT2a, N0, M0, PSA equal or more than 10 and less than 20, Grade Group 1); (cT2b-c, N0, M0, PSA less than 20, Grade Group 1); IIB: T1-2, N0, M0, PSA less than 20, Grade Group 2; IIC: (T1-2, N0, M0, PSA less than 20, Grade Group 3); (T1-2, N0, M0, PSA less than 20, Grade Group 4). cT1a: Prostate cancer in which the tumor is an incidental histologic finding in 5% or less of tissue resected. cT1b: Prostate cancer in which the tumor is an incidental histologic finding in more than 5% of tissue resected. cT1c: Prostate cancer in which the tumor is identified by needle biopsy found in one or both sides, but not palpable. cT2a: Prostate cancer in which the tumor involves one-half of one side or less. cT2b: Prostate cancer in which the tumor involves more than one-half of one side but not both sides. cT2c: Prostate cancer in which the tumor involves both sides. T1: Prostate cancer with clinically inapparent tumor that is not palpable. T2: Prostate cancer in which the tumor is palpable and confined within the prostate. N0: Prostate cancer with no positive regional nodes. M0: Prostate cancer without evidence of distant metastasis. Grade Group 1: Gleason Score 6 or less, Gleason Pattern 3 or less+3. Grade Group 2: Gleason Score 7, Gleason Pattern 3+4. Grade Group 3: Gleason Score 7, Gleason Pattern 4+3. Grade Group 4: Gleason Score 8, Gleason Pattern 4+4. (AJCC 8th ed.)


name: Subglottic Cancer Pathologic Distant Metastasis TNM Finding v6

description: A pathologic finding about one or more characteristics of subglottic cancer, following the rules of the TNM AJCC v6 classification system as they pertain to distant metastases.


ROS1 Gene Rearrangement Negative

description: A genetic finding indicating that rearrangement of the ROS1 gene has not been detected in a sample.


name: secondary carcinoid tumor of other sites

description: Evidence of secondary carcinoid tumors of other sites.


iRECIST Complete Response

description: The disappearance of all signs of cancer following an initial apparent radiographic progression.


name: Merkel Cell Carcinoma pN3 TNM Finding v8

description: Merkel cell carcinoma with in-transit metastasis (discontinuous from primary tumor; located between primary tumor and draining regional nodal basin, or distal to the primary tumor) with lymph node metastasis. (from AJCC 8th Ed.)


name: Childhood Retinoblastoma by Toronto Guidelines v2 Stage, Tier 1

description: A term that refers to the staging of childhood retinoblastoma according to the tier 1 Toronto childhood cancer staging guidelines v2.


Grade 3 Urinary Tract Infection, CTCAE

description: IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated


Grade 3 Periorbital Edema, CTCAE

description: Edema associated with visual disturbance; increased intraocular pressure, glaucoma or retinal hemorrhage; optic neuritis; diuretics indicated; operative intervention indicated


Colitis, CTCAE

description: A disorder characterized by inflammation of the colon.


Childhood Liver Neoplasm

description: A benign or malignant neoplasm that affects the liver and occurs during childhood.


Grade 2 Dry Mouth, CTCAE

description: Moderate symptoms; oral intake alterations (e.g., copious water, other lubricants, diet limited to purees and/or soft, moist foods); unstimulated saliva 0.1 to 0.2 ml/min


Adenosarcoma pN0 TNM Finding v7

description: No regional lymph node metastasis. (from AJCC 7th Ed.)


Malignant neoplasm overlapping lip site

description: Evidence of a malignant neoplasm of overlapping sites of the lip.


name: Grade 4 Retina Intra-Operative Injury, CTCAE


Physical Examination Finding

description: The result of an evaluation of the body and its functions using visual inspection, palpation, percussion, or auscultation that is performed to determine the presence, absence, or degree of a condition.


Radiating Pain

description: A sensation of discomfort or distress that spreads from one anatomic location to another.


Cervical Cancer pN0 TNM Finding v8

description: Cervical cancer with no regional lymph node metastasis. (from AJCC 8th Ed.)


Grade 3 Personality Change, CTCAE

description: Severe personality change; hospitalization not indicated


Distant Metastases Pathology Cancer

description: Evidence of distant metastases pathology cancer.


Liver Cancer pT0 TNM Finding v6

description: Liver cancer with no evidence of a primary tumor. (from AJCC 6th Ed.)


Relapse of Prior Malignancy

description: Clinical and/or laboratory evidence of reemergence of a malignancy after a period of remission.


name: Jejunum and Ileum Neuroendocrine Tumor pT4 TNM Finding v8

description: Jejunum and ileum neuroendocrine tumor invading visceral peritoneum (serosa) or other organs or adjacent structures. (from AJCC 8th Ed.)


name: Human Immunodeficiency Virus Infection Complicating Pregnancy, Second Trimester

description: Evidence of human immunodeficiency virus infection complicating pregnancy in the second trimester.


Grade 1 Vertigo, CTCAE

description: Mild symptoms


Mucosal Nevus

description: A nevus that arises from a mucosal site.


Melanoma of the Uvea pNX TNM Finding v7

description: Melanoma of the uvea in which the regional lymph nodes cannot be assessed.  (from AJCC 7th Ed.)


name: Metastatic Bladder Large Cell Neuroendocrine Carcinoma

description: Bladder large cell neuroendocrine carcinoma that has spread to another anatomical site.


name: Primary Cutaneous Diffuse Large B-Cell Lymphoma, Other

description: A rare type of primary cutaneous diffuse large B-cell lymphoma that does not belong in the group of primary cutaneous diffuse large B-cell lymphomas, leg type, or the group of primary cutaneous follicle center lymphomas.  It includes subtypes/entities of diffuse large B-cell lymphoma (e.g. intravascular large B-cell lymphoma, plasmablastic lymphoma, T-cell/histiocyte rich lymphoma) that can involve the skin as the primary anatomic site.  Such cases, unlike their nodal counterparts, usually have an excellent prognosis.


name: Sézary's disease of intra-abdominal lymph nodes

description: Evidence of Sezary disease in the intra-abdominal lymph nodes.


name: Exocrine Pancreatic Cancer Pathologic Primary Tumor TNM Finding v8

description: A pathologic finding about one or more characteristics of exocrine pancreatic cancer, following the rules of the TNM AJCC v8 classification system as they pertain to staging of the primary tumor.


Grade 1 Insomnia, CTCAE

description: Mild difficulty falling asleep, staying asleep or waking up early


PSA Level Greater than 0.4

description: A blood concentration of prostate specific antigen greater than 0.4 ng/mL.


name: Grade 5 Ileum Stricture or Stenosis, CTCAE


name: Grade 2 Uterus Infection with Unknown Absolute Neutrophil Count, CTCAE


Lung Cancer pT1a TNM Finding v7

description: Lung cancer with a tumor size of 2 cm or less in greatest dimension, surrounded by lung or visceral pleura and without bronchoscopic evidence of invasion more proximal than the lobar bronchus (i.e., not in the main bronchus). The uncommon superficial tumor of any size with its invasive component limited to the bronchial wall, which may extend proximal to the main bronchus, is also classified as T1a. (from AJCC 7th Ed.)


name: Grade 3 Surgical and Medical Procedures - Other, Specify, CTCAE

description: Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL


name: Primary Cutaneous B-Cell/T-Cell (Non-MF/SS) Lymphoma T2 TNM Finding v8

description: Regional skin involvement: multiple lesions limited to one body region or two contiguous body regions.  (from AJCC 8th Ed.)


Grade 1 Fatigue, CTCAE

description: Fatigue relieved by rest


Metastatic ocular melanoma

description: Ocular melanoma that has spread from its original site of growth to another anatomic site.


Grade 1 Bronchial Stricture, CTCAE

description: Asymptomatic; clinical or diagnostic observations only; intervention not indicated


name: Diabetes Mellitus due to Underlying Condition with Mild Non-Proliferative Diabetic Retinopathy without Macular Edema, Right Eye

description: Evidence of diabetes mellitus due to underlying condition with mild non-proliferative diabetic retinopathy without macular edema in the right eye.


Hiccups, CTCAE

description: A disorder characterized by repeated gulp sounds that result from an involuntary opening and closing of the glottis. This is attributed to a spasm of the diaphragm.


name: Right Middle Anterior Fibromuscular Stroma of Prostate

description: The portion of the fibromuscular stroma of the prostate that is located on the anatomical right side of the middle division of the anterior lobe.


name: Grade 5 Vein Infection with Unknown Absolute Neutrophil Count, CTCAE


name: Merkel Cell Carcinoma of Unspecified Eyelid, Including Canthus

description: Evidence of Merkel cell carcinoma of unspecified eyelid including the canthus.


Grade 3 Ventricular Tachycardia, CTCAE

description: Symptomatic, urgent intervention indicated


name: Grade 4 Spleen Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


name: Grade 2 Bruising in the Absence of Grade 3 or Grade 4 Thrombocytopenia, CTCAE


name: Grade 5 Intra-Abdominal Hemorrhage, CTCAE

description: Death


name: Grade 3 Pelvis Infection NOS with Unknown Absolute Neutrophil Count, CTCAE


name: Grade 2 Flashing Lights and Floaters in Vision, CTCAE


Cortical Cataract Grade 4

description: A stage of cortical cataract characterized by greater than 90% of the intrapupillary space obscured by opacity. (Modified LOCS II)


Grade 2 Olfactory Nerve Disorder, CTCAE

description: Moderate symptoms; limiting instrumental ADL


Grade 2 Jejunal Perforation, CTCAE

description: Invasive intervention not indicated


name: Type 2 Diabetes Mellitus with Proliferative Diabetic Retinopathy with Combined Traction Retinal Detachment and Rhegmatogenous Retinal Detachment, Unspecified Eye

description: Evidence of type 2 diabetes mellitus with proliferative diabetic retinopathy with combined traction retinal detachment and rhegmatogenous retinal detachment in an unspecified eye.


name: Clinical Stage IIA Esophageal Adenocarcinoma AJCC v8

description: Stage IIA includes: T1, N1, M0. T1: Tumor invades the lamina propria, muscularis mucosae, or submucosa. N1: Tumor with metastasis in one or two regional lymph nodes. M0: No distant metastasis. (AJCC 8th ed.)


name: Grade 5 Urethra Stricture or Stenosis, CTCAE


name: Low Grade Biliary Intraepithelial Neoplasia

description: Biliary intraepithelial neoplasia characterized by the presence of low grade epithelial dysplasia.


Grade 3 Pharyngitis, CTCAE

description: IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated


Grade 4 Salivary Gland Infection, CTCAE

description: Life-threatening consequences; urgent intervention indicated


48,XXXY Karyotype

description: An abnormal sex chromosome karyotype where the individual has three copies of the X chromosome and one copy of the Y chromosome. The normal autosomal karyotype is present.


name: Grade 5 Prostate Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


name: Adrenal Cortical Carcinoma Pathologic Distant Metastasis TNM Finding v8

description: A pathologic finding about one or more characteristics of adrenal cortical carcinoma, following the rules of the TNM AJCC v8 classification system as they pertain to distant metastases.


Gallbladder Neuroendocrine Tumor G2

description: A well differentiated, intermediate grade neoplasm with neuroendocrine differentiation that arises from the gallbladder. The mitotic count is 2-20 per 10 HPF and/or the Ki67 index is 3 to 20 percent.


name: Other Stimulant Abuse with Intoxication, Uncomplicated

description: Evidence of other stimulant abuse with intoxication, uncomplicated not specified elsewhere.


name: Artery Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


name: Other Specified Diabetes Mellitus with Moderate Nonproliferative Diabetic Retinopathy without Macular Edema

description: Evidence of other specified diabetes mellitus with moderate nonproliferative diabetic retinopathy without macular edema not specified elsewhere.


name: Grade 3 Lung Infection with Unknown Absolute Neutrophil Count, CTCAE


Encephalopathy, CTCAE 5.0

description: A disorder characterized by a pathologic process involving the brain.


name: Pleural Malignant Mesothelioma cM0 TNM Finding v8

description: Pleural malignant mesothelioma without distant metastasis. (from AJCC 8th Ed.)


Increased Follicles

description: Increased number and/or size of follicles.


name: H-type congenital tracheoesophageal fistula

description: Congenital tracheoesophageal fistula without esophageal atresia.


Drug Metabolism Alteration

description: A finding indicating a deficiency or excess in metabolism of one or more drugs.


Testicular Typical Seminoma

description: A testicular seminoma characterized by the presence of uniform round germ cells with glycogen-rich cytoplasm and large nuclei, and a lymphocytic infiltrate.


Grade 4 Laryngeal Hemorrhage, CTCAE

description: Life-threatening consequences; urgent intervention indicated (e.g., tracheotomy or intubation)


Grade 3 Cecal Hemorrhage, CTCAE

description: Transfusion indicated; invasive intervention indicated; hospitalization


name: Overlapping malignant neoplasm of esophagus

description: Evidence of a malignant neoplasm of overlapping sites of the esophagus.


name: Cerebral Infarction due to Thrombosis of Left Middle Cerebral Artery

description: Evidence of cerebral infarction due to a thrombosis of the left middle cerebral artery.


name: Grade 4 Salivary Gland Intra-Operative Injury, CTCAE


name: Non-Neoplastic Connective and Soft Tissue Disorder

description: A non-neoplastic disorder that affects the connective and soft tissue.


name: Burkitt's tumor or lymphoma involving lymph nodes of inguinal region and lower limb

description: Evidence of Burkitt lymphoma in the lymph nodes of inguinal region and lower limb.


name: Grade 3 Extraocular Muscle Paresis, CTCAE

description: Bilateral paresis or unilateral paresis causing double vision in peripheral gaze, but not in central gaze


Peritoneal Pain

description: Painful sensation in the peritoneum.


Dental Caries, CTCAE

description: A disorder characterized by the decay of a tooth, in which it becomes softened, discolored and/or porous.


description: Evidence of polymyositis with respiratory involvement.


Neonatal Hypertension, AE

description: An adverse event in a newborn characterized by abnormally high blood pressure.


Subglottic Cancer cM0 TNM Finding v7

description: Subglottic cancer without evidence of distant metastasis. (from AJCC 7th Ed.)


Testicular Cancer pT1 TNM Finding v8

description: Testicular cancer which is limited to testis (including rete testis invasion) without lymphovascular invasion. (from AJCC 8th Ed.)


name: Cutaneous Squamous Cell Carcinoma of the Head and Neck cNX TNM Finding v8

description: Cutaneous squamous cell carcinoma of the head and neck in which the regional lymph nodes cannot be assessed.  (from AJCC 8th Ed.)


name: Cerebral Infarction due to Thrombosis of Left Posterior Cerebral Artery

description: Evidence of cerebral infarction due to a thrombosis of the left posterior cerebral artery.


name: Metastatic malignant neoplasm to respiratory and digestive systems

description: Evidence of secondary malignant neoplasm of respiratory and digestive organs.


name: Type 2 Diabetes Mellitus with Mild Nonproliferative Diabetic Retinopathy without Macular Edema, Bilateral

description: Evidence of type 2 diabetes mellitus with mild nonproliferative diabetic retinopathy without macular edema that is bilateral.


Grade 4 Hematuria, CTCAE

description: Life-threatening consequences; urgent invasive intervention indicated


Grade 2 Vestibular Disorder, CTCAE

description: Symptomatic; limiting instrumental ADL


Grade 3 Mediastinal Infection, CTCAE

description: IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated


Neoplasm by Morphology

description: A classification system grouping neoplasms according to their cellular characteristics.


name: Duodenum/Ampulla/Jejunum/Ileum Neuroendocrine Tumor pNX TNM Finding v7

description: Duodenum/ampulla/jejunum/ileum neuroendocrine tumor in which regional lymph nodes cannot be assessed. (from AJCC 7th Ed.)


Hypercalcemia, CTCAE

description: A disorder characterized by laboratory test results that indicate an elevation in the concentration of calcium (corrected for albumin) in blood.


name: Recurrent Platinum-Resistant Fallopian Tube High Grade Serous Adenocarcinoma

description: The reemergence of platinum-resistant fallopian tube high-grade serous adenocarcinoma after a period of remission.


name: Anemia in other chronic diseases classified elsewhere

description: Evidence of anemia in other chronic diseases classified elsewhere.


Grade 5 Laryngeal Hemorrhage, CTCAE

description: Death


name: Sedative, Hypnotic or Anxiolytic lnduced Dependence with Persisting Amnestic Disorder

description: Evidence of sedative, hypnotic or anxiolytic induced dependence with persisting amnestic disorder.


name: Nasopharyngeal Cancer pT2 TNM Finding v8

description: Nasopharyngeal cancer with extension to parapharyngeal space, and/or adjacent soft tissue involvement (medial pterygoid, lateral pterygoid, prevertebral muscles). (from AJCC 8th Ed.)


name: Other specified malignant neoplasm of skin of right lower eyelid, including canthus

description: Evidence of other specified malignant neoplasm of skin of right lower eyelid including the canthus not specified elsewhere.


name: Uterine Corpus Adenosarcoma pN0(i+) TNM Finding v8

description: Uterine corpus adenosarcoma with isolated tumor cells in regional lymph node(s) no greater than 0.2 mm. (from AJCC 8th Ed.)


name: Hepatic Failure, Unspecified without Coma

description: Evidence of hepatic failure, unspecified without coma.


name: Type 2 Diabetes Mellitus with Stable Proliferative Diabetic Retinopathy, Right Eye

description: Evidence of type 2 diabetes mellitus with stable proliferative diabetic retinopathy in the right eye.


Short Stature Homeobox Deficiency

description: A rare genetic deficiency characterized by mutations in the SHOX gene and reduced expression or function of the SHOX protein. It results in the disruption of normal bone development and growth starting before birth. It manifests with skeletal abnormalities and short stature.


name: Chronic Lymphocytic Leukemia of B-Cell Type not Having Achieved Remission

description: Evidence of chronic lymphocytic leukemia of B-cell type not having achieved remission.


Bladder cancer stage IV

description: A carcinoma that arises from the bladder and has metastasized to another anatomic site.


PMS2 Negative

description: An indication that expression of PMS2 has not been detected in a sample.


Grade 2 Gastrointestinal Fistula, CTCAE

description: Symptomatic, invasive intervention not indicated


name: Grade 4 Eye Infection NOS Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


name: Other Psychoactive Substance Abuse with Intoxication, Unspecified

description: Evidence of other psychoactive substance abuse with intoxication not specified elsewhere.


name: Grade 3 Small Bowel Perforation NOS, CTCAE


Edema Cerebral, CTCAE

description: A disorder characterized by swelling due to an excessive accumulation of fluid in the brain.


name: High Grade Mucinous Carcinoma Peritonei with Signet Ring Cells

description: A high-grade mucinous adenocarcinoma that has spread to the peritoneum and is characterized by the presence of signet ring malignant cells.


Cervical Cancer cM0 TNM Finding v9

description: Cervical cancer in which there is no evidence of distant metastasis. (from AJCC 9th Ed.)


name: Rheumatoid Arthritis of Left Elbow with Involvement of Organs and Systems

description: Evidence of rheumatoid arthritis of left elbow with involvement of organs and systems.


name: Grade 2 Scleral Necrosis and Melt, CTCAE


Grade 2 Dyspareunia, CTCAE

description: Moderate discomfort or pain associated with vaginal penetration; discomfort or pain partially relieved with use of vaginal lubricants or estrogen


Bladder Melanoma

description: A rare melanoma that arises from the bladder mucosa.


name: Grade 5 Central Nervous System Hemorrhage, CTCAE


name: Dermatopolymyositis, Unspecified without Myopathy

description: Evidence of dermatopolymyositis, unspecified without myopathy.


name: Pleural Mesothelioma Clinical TNM Finding v7

description: A clinical finding about one or more characteristics of pleural mesothelioma, following the rules of the TNM AJCC v7 classification system.  The clinical staging depends on imaging most frequently computed tomography (CT) and more recently FDG positron emission tomography (FDG-PET) scanning.  (from AJCC 7th Ed.)


Testosterone Deficiency, CTCAE

description: A disorder characterized by low testosterone.


Extranodal Lymphoma

description: A non-Hodgkin or Hodgkin lymphoma that arises from an anatomic site other than a lymph node.


name: Testicular Cancer Pathologic TNM Finding v7

description: A pathologic finding about one or more characteristics of testicular cancer, following the rules of the TNM AJCC v7 classification system.  Histologic examination of the orchiectomy specimen must be used for the pathologic examination.  (from AJCC 7th Ed.)


Renal Radiation Injury

description: Radiation injury of the kidney.


name: Mucosal Melanoma of the Head and Neck pN1 TNM Finding v8

description: Mucosal melanoma of the head and neck with regional lymph node metastases. (from AJCC 8th Ed.)


Adrenal Cancer pM1 TNM Finding v7

description: Adrenal cancer with distant metastasis. (from AJCC 7th Ed.)


name: Anus Mucositis or Stomatitis by Clinical Examination Classification, CTCAE


Visceral Arterial Ischemia, CTCAE

description: A disorder characterized by a decrease in blood supply due to narrowing or blockage of a visceral (mesenteric) artery.


Non-Neoplastic Bladder Disorder

description: A non-neoplastic disorder that affects the urinary bladder. Representative examples include cystitis, cystolithiasis, and urinary bladder rupture.


Stage Group Pathology Cancer

description: Evidence of stage group pathology cancer.


name: Follicular Lymphoma Grade III, Unspecified, Intrathoracic Lymph Nodes

description: Evidence of unspecified follicular lymphoma grade III in the intrathoracic lymph nodes.


name: Spleen Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


name: Gallbladder Cancer pM1 TNM Finding v6 and v7

description: Gallbladder cancer with distant metastasis. (from AJCC 6th and 7th Eds.)


name: Non-insulin-dependent diabetes mellitus with other specified complications

description: Evidence of type 2 diabetes mellitus with other specified complication.


Stage IIIB Appendix Carcinoma AJCC v8

description: Stage IIIB includes: (T3, N1, M0); (T4, N1, M0). T3: Tumor invades through the muscularis propria into the subserosa or the mesoappendix. T4: Tumor invades the visceral peritoneum, including the acellular mucin or mucinous epithelium involving the serosa of the appendix or mesoappendix, and/or directly invades adjacent organs or structures. N1: One to three regional lymph nodes are positive (tumor in lymph node measuring 0.2 mm or more) or any number of tumor deposits is present, and all identifiable lymph nodes are negative. M0: No distant metastasis. (AJCC 8th ed.)


name: Peripheral T-Cell Lymphoma, not Classified, Lymph Nodes of Inguinal Region and Lower Limb

description: Evidence of unclassified peripheral T-cell lymphoma in the lymph nodes of the inguinal region and lower limb.


name: Ampulla of Vater Intestinal-Type Adenocarcinoma

description: An invasive adenocarcinoma arising from the ampulla of Vater. Morphologically, it is characterized by the presence of intestinal-type malignant epithelial cells.


name: Unspecified Atherosclerosis of Native Arteries of Extremities, Other Extremity

description: Evidence of unspecified atherosclerosis of native arteries of extremities in another extremity.


name: Refractory T/NK-Cell Lymphoproliferative Disorder

description: T/NK-cell lymphoproliferative disorder that is resistant to treatment.


Acute Myeloid Leukemia with STAT3-RARA

description: Acute myeloid leukemia with variant RARA rearrangement and expression of STAT3-RARA fusion protein.


name: Carcinoma of the Eyelid Pathologic Regional Lymph Nodes TNM Finding v7

description: A pathologic finding about one or more characteristics of carcinoma of the eyelid, following the rules of the TNM AJCC v7 classification system as they pertain to staging of regional lymph nodes.


name: Skin Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


Diffuse hyperplasia

description: Hyperplasia characterized by the presence of a diffuse cellular infiltrate.


name: Grade 2 Voice Changes and Dysarthria, CTCAE


Chronic Cancer Pain

description: Chronic pain that results from cancer and/or its treatment. The mechanism for chronic cancer pain may be  inflammatory, neuropathic, ischemic, and/or mechanical in nature.


Testicular Cancer cN3 TNM Finding v7

description: Metastasis with a lymph node mass more than 5 cm in greatest dimension. (from AJCC 7th Ed.)


name: Monoplegia of Upper Limb following Non-Traumatic Subarachnoid Hemorrhage Affecting Left Non-Dominant Side

description: Evidence of monoplegia of upper limb following non-traumatic subarachnoid hemorrhage affecting left non-dominant side.


name: Distal Bile Duct Cancer pN0 TNM Finding v7

description: Distal bile duct cancer with no regional lymph node metastasis. (from AJCC 7th Ed.)


name: Type 2 Diabetes Mellitus with Moderate Nonproliferative Diabetic Retinopathy without Macular Edema

description: Evidence of type 2 diabetes mellitus with moderate nonproliferative diabetic retinopathy without macular edema.