name: Stage IIIA Childhood Hodgkin Lymphoma by Toronto Guidelines v2

description: Involvement of lymph node regions on both sides (above and below) of the diaphragm. This may be accompanied by extra-lymphatic extension in association with adjacent lymph node involvement (i.e., local extension from a lymph node area into a nearby organ) and/or involvement of spleen. No constitutional symptoms are recorded. This definition applies to both tiers (tier 1 and 2). (Childhood cancer staging for population registries according to the Toronto Childhood Cancer Stage Guidelines - Version 2. Cancer Council Queensland and Cancer Australia: Brisbane, Australia; 2021.)


Hypoperfusion

category: biolink:Disease biolink:DiseaseOrPhenotypicFeature biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing

description: No component of the tumor exhibits perfusion equal to or greater than cerebellar gray matter, excluding encased or grossly visible intrinsic vasculature.


Gastric Cancer pN3 TNM Finding v7

category: biolink:PhenotypicFeature biolink:DiseaseOrPhenotypicFeature biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing

description: Gastric cancer with metastasis in seven or more regional lymph nodes. (from AJCC 7th Ed.)


Body Habitus Artifact

description: Artifacts related to the physique or body build of the patient.


name: Ocular Adnexal Lymphoma Pathologic TNM Finding v7

description: A pathologic finding about one or more characteristics of ocular adnexal lymphoma, following the rules of the TNM AJCC v7 classification system.


Grade 2 Rash Maculo-Papular, CTCAE

description: Macules/papules covering 10-30% BSA with or without symptoms (e.g., pruritus, burning, tightness); limiting instrumental ADL; rash covering > 30% BSA with or without mild symptoms


6/6 HLA Match

description: Complete HLA matching for HLA-A, -B and -DRB1 loci.


Grade 2 Oral Dysesthesia, CTCAE

description: Moderate pain; interfering with oral intake


Tubular Neoplasm

description: A benign or malignant neoplasm characterized by the presence of a tubular architecture. This category includes tubular adenomas and tubular carcinomas.


pN3 TNM Finding

description: A pathologic regional lymph node TNM finding. The definition of pN3 finding depends on the particular type of cancer that it refers to; for example, for bladder cancer, pN3 finding is defined as follows: cancer with lymph node metastasis to the common iliac lymph nodes. (from AJCC 8th Ed.)


name: Melanoma in situ of other and unspecified parts of face

description: Evidence of melanoma in situ of other and unspecified parts of face.


name: Lacrimal Drainage System Exophytic Papilloma

description: A benign exophytic papillary neoplasm that arises from the lacrimal drainage system. It consists of fibrovascular cores lined by epithelial cells.


Grade 2 Gastric Ulcer, CTCAE

description: Symptomatic; altered GI function; medical intervention indicated; limiting instrumental ADL


name: Abnormal Blood Chemistry and Hematology Test Result

description: A laboratory test result that indicates the presence of abnormal blood chemistry and/or hematology values.


Grade 5 Ventricular Tachycardia, CTCAE

description: Death


name: Uterine Corpus Adenosarcoma Pathologic Distant Metastasis TNM Finding v8

description: A pathologic finding about one or more characteristics of uterine corpus adenosarcoma, following the rules of the TNM AJCC v8 classification system as they pertain to distant metastases.


name: Grade 4 Pharynx Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


name: Carcinoma of the Lacrimal Gland pT4c TNM Finding v7

description: Carcinoma of the lacrimal gland with tumor invading adjacent structures (brain, sinus, pterygoid fossa, temporal fossa).  (from AJCC 7th Ed.)


name: Hodgkin's disease mixed cellularity stage I subdiaphragmatic


name: Beta-2 Microglobulin Greater than 5.5 g/mL

description: A laboratory test result indicating the presence of high levels of beta-2 microglobulin in blood or urine, exceeding 5.5 g/mL.


Anal infection

description: An infectious process affecting the anal area.


name: Perihilar Bile Duct Cancer Clinical TNM Finding v8

description: A clinical finding about one or more characteristics of perihilar bile duct cancer, following the rules of the TNM AJCC v8 classification system.


Grade 1 Encephalopathy, CTCAE

description: Mild symptoms


Other Seizures

description: Evidence of other seizures not specified elsewhere.


name: Cutaneous Squamous Cell Carcinoma of the Head and Neck cN3 TNM Finding v8

description: Cutaneous squamous cell carcinoma of the head and neck with metastasis in a lymph node larger than 6 cm in greatest dimension and ENE(-); or metastasis in any lymph node(s) and clinically overt ENE(+). (from AJCC 8th Ed.)


name: Grade 4 Rectum Mucositis or Stomatitis by Functional or Symptomatic Classification, CTCAE


Reserve Cell Hyperplasia

description: Hyperplasia of the immature cells located between the surface columnar epithelium and the basal layer.


Hematocrit Less than 45 Percent

description: An indication that the volume of red blood cells in a whole blood sample is less than 45 percent of the total blood volume.


Grade 3 Pleural Hemorrhage, CTCAE

description: >1000 ml of blood evacuated; persistent bleeding (150-200 ml/hr for 2-4 hr); persistent transfusion indicated; elective operative intervention indicated; hospitalization


Physical Entrapment

description: Patient becomes entangled or caught in a bed, particularly in side rails, or mattress, or head/foot boards.


name: Metastatic malignant neoplasm to retroperitoneum and peritoneum

description: Evidence of secondary malignant neoplasm of retroperitoneum and peritoneum.


CDKN2A-p16 Status

description: An indication of whether CDKN2A-p16 expression has been detected in a sample.


name: Atherosclerosis of Other Type of Bypass Graft(s) of the Extremities with Intermittent Claudication, Other Extremity

description: Evidence of atherosclerosis of other type of bypass graft(s) of the extremities with intermittent claudication in the other extremity.


name: Hodgkin's Disease, Lymphocyte Depletion, Reticular

description: A lymphocyte depleted Hodgkin lymphoma characterized by the presence of reticular fibrosis.


name: Type 1 Diabetes Mellitus with Moderate Nonproliferative Diabetic Retinopathy with Macular Edema, Right Eye

description: Evidence of type 1 diabetes mellitus with moderate nonproliferative diabetic retinopathy with macular edema in the right eye.


name: Lugano Classification Limited Stage Hodgkin Lymphoma AJCC v8

description: Limited stage Hodgkin lymphoma based on the Lugano classification criteria. It includes stages I, IE, II, and IIE. (from AJCC 8th Ed.)


Restlessness, CTCAE

description: A disorder characterized by an inability to rest, relax or be still.


name: Neuroendocrine ADH Secretion Abnormality, CTCAE


name: Juvenile Arthritis, Unspecified, Right Knee

description: Evidence of unspecified juvenile arthritis in the right knee.


name: Ampulla of Vater Cancer pT3b TNM Finding v8

description: Ampulla of Vater cancer with tumor extending more than 0.5 cm into the pancreas, or extending into peripancreatic tissue or duodenal serosa without involvement of the celiac axis or superior mesenteric artery. (from AJCC 8th Ed.)


Lacrimal Gland Acinic Cell Carcinoma

description: An extremely rare, low-grade, salivary gland-type carcinoma that arises from the lacrimal gland. It exhibits acinar differentiation.


name: Gastric Neuroendocrine Tumor TNM Finding v8

description: A finding about one or more characteristics of a gastric neuroendocrine tumor, following the rules of the TNM AJCC v8 classification system. This classification system applies to gastric "carcinoid" tumors (NET G1 and G2, and rare well-differentiated G3). Gastric high-grade neuroendocrine carcinoma and gastric mixed adenoneuroendocrine carcinoma are not included in this classification system. (from AJCC 8th Ed.)


Testicular Cancer cNX TNM Finding v8

description: Testicular cancer in which the regional lymph nodes cannot be assessed. (from AJCC 8th Ed.)


name: Drug or Chemical Induced Diabetes Mellitus with Proliferative Diabetic Retinopathy with Combined Traction Retinal Detachment and Rhegmatogenous Retinal Detachment, Left Eye

description: Evidence of drug or chemical induced diabetes mellitus with proliferative diabetic retinopathy with combined traction retinal detachment and rhegmatogenous retinal detachment in the left eye.


name: Grade 2 Cranial Nerve V Neuropathy, CTCAE


name: Maxillary Sinus Cancer Pathologic Primary Tumor TNM Finding v8

description: A pathologic finding about one or more characteristics of maxillary sinus cancer, following the rules of the TNM AJCC v8 classification system as they pertain to staging of the primary tumor.


Grade 2 Hypothyroidism, CTCAE

description: Symptomatic; thyroid replacement indicated; limiting instrumental ADL


alcohol dependence in remission

description: Evidence of alcohol dependence, in remission.


Urethral Infection

description: A bacterial, viral, or fungal infectious process affecting the urethra.


Biliary Intraepithelial Neoplasia-2

description: Biliary intraepithelial neoplasia characterized by the presence of moderate epithelial atypia.


name: Hepatocellular Carcinoma pT3 TNM Finding v8

description: Hepatocellular carcinoma with multiple tumors, at least one of which is larger than 5 cm. (from AJCC 8th Ed.)


Recurrent Malignant Brain Neoplasm

description: The reemergence of a malignant brain neoplasm after a period of remission.


Alcoholic Gastritis with Bleeding

description: Evidence of alcoholic gastritis with bleeding.


Abdominal Rhabdomyosarcoma

description: Rhabdomyosarcoma involving the organs and structures in the abdomen.


name: Large Bowel Mucositis or Stomatitis by Clinical Examination Classification, CTCAE


Uveal Melanoma cM1a TNM Finding v8

description: Uveal melanoma with largest diameter of the largest metastasis 3.0 cm or less. (from AJCC 8th Ed.)


Grade 1 Hallucinations, CTCAE

description: Mild hallucinations (e.g., perceptual distortions)


Injection site thrombophlebitis

description: Thrombophlebitis in the veins surrounding an injection site.


Malignant Neoplasm of Right Upper Limb

description: Evidence of a malignant neoplasm of the right upper limb.


name: Refractory Accelerated Phase Chronic Myeloid Leukemia, BCR-ABL1 Positive

description: Accelerated phase chronic myeloid leukemia, BCR-ABL1 positive that is resistant to treatment.


name: Rheumatoid Vasculitis with Rheumatoid Arthritis of Left Wrist

description: Evidence of rheumatoid vasculitis with rheumatoid arthritis of left wrist.


Data Evaluable QC Metrics Good

description: An indication that the data can be evaluated and that the quality control metrics were good.


name: Major Salivary Gland Cancer pN2c TNM Finding V8

description: Major salivary gland cancer with metastasis in bilateral or contralateral lymph nodes, none more than 6 cm in greatest dimension and ENE(-). (from AJCC 8th Ed.)


name: Post-Dysenteric Arthropathy, Unspecified Knee

description: Evidence of post-dysenteric arthropathy in an unspecified knee.


Cervical Cancer pT3b TNM Finding v8

description: Cervical cancer extending to pelvic wall and/or causing hydronephrosis or nonfunctioning kidney. (from AJCC 8th Ed.)


Rare Diseases

description: A non-neoplastic or neoplastic disorder that is uncommon.


Cervical Cancer cT1b1 TNM Finding v8

description: Cervical cancer with clinically visible lesion 4.0 cm or less in greatest dimension. (from AJCC 8th Ed.)


name: Systemic Atrophy Affecting Central Nervous System in Other Diseases Classified Elsewhere

description: Evidence of systemic atrophy affecting central nervous system in other diseases classified elsewhere.


name: Microvascular Thrombosis Related to COVID-19

description: Blood clot formation in the small blood vessels of the body in a patient with probable or confirmed acute COVID-19.


name: Ann Arbor Stage II Lymphocyte-Depleted Classic Hodgkin Lymphoma

description: Ann Arbor Classification: Stage II: Involvement of two or more lymph node regions on the same side of the diaphragm (II); or localized involvement of a single extralymphatic organ or site in association with regional lymph node involvement with or without involvement of other lymph node regions on the same side of the diaphragm (IIE).


name: Grade 5 Ureteric Anastomotic Leak, CTCAE

description: Death


name: Grade 2 Alkaline Phosphatase Increased, CTCAE

description: >2.5-5.0 x ULN if baseline was normal; >2.5-5.0 x baseline if baseline was abnormal


Prosthetic Valve Thrombosis

description: The formation of a blood clot that is attached to or near an artificial heart valve; this can cause dysfunction of the valve, and possibly lead to an embolic event should the thrombus become dislodged.


Grade 3 Postoperative Hemorrhage, CTCAE

description: Transfusion indicated of >=2 units (10 cc/kg for pediatrics) pRBCs; invasive intervention indicated; hospitalization


Vulvar Dysplastic Melanocytic Nevus

description: A rare, elevated and pigmented, compound or junctional nevus that arises from the vulva. It affects women in their reproductive years and may be associated with the presence of dysplastic nevi in other anatomic areas. It is characterized by the presence of epithelioid or spindle-shaped melanocytes exhibiting nuclear pleomorphism and prominent nucleoli.


name: Small Intestine Cancer cM0 TNM Finding v8

description: Small intestine cancer without evidence of distant metastasis. (from AJCC 8th Ed.)


Grade 4 Conjunctivitis, CTCAE

description: Best corrected visual acuity of 20/200 or worse in the affected eye


name: Nasal Cavity and Ethmoid Sinus Cancer pT3 TNM Finding v6 and v7

description: Nasal cavity and ethmoid sinus cancer with tumor invading the medial wall or floor of the orbit, maxillary sinus, palate, or cribriform plate. (from AJCC 6th and 7th Eds.)


name: Other Secondary Malignancy Possibly Related to Cancer Treatment, CTCAE


name: Eyelid Carcinoma Clinical Regional Lymph Nodes TNM Finding v8

description: A clinical finding about one or more characteristics of eyelid carcinoma, following the rules of the TNM AJCC v8 classification system as they pertain to staging of regional lymph nodes.


name: Grade 5 Jejunum Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


Equivocal Laboratory Test Result

description: A laboratory test result that indicates that a specific disease, condition, or attribute being assessed is not clearly present or absent.


45,XO Karyotype

description: An abnormal sex chromosome karyotype where the individual is missing either a second X chromosome or the Y chromosome. The normal autosomal karyotype is present. This karyotype is associated with Turner Syndrome.


Grade 4 Hepatitis B Reactivation, CTCAE

description: Life-threatening consequences; urgent intervention indicated; severe decompensated liver function (e.g., coagulopathy, encephalopathy, coma)


name: Appendiceal Carcinoma pT3 TNM Finding v7

description: Appendiceal carcinoma with tumor invading through muscularis propria into subserosa or into mesoappendix. (from AJCC 7th Ed.)


Reiter's Disease, Left Hip

description: Evidence of Reiter's disease in the left hip.


Liver Cancer pT3 TNM Finding v6

description: Liver cancer with multiple tumors at least one of which is more than 5 cm in size, or a tumor involving a major branch of the portal or hepatic vein. (from AJCC 6th Ed.)


name: Borderline Ovarian Serous Papillary Cystic Tumor

description: A neoplasm of low malignant potential arising from the ovary. It is characterized by the presence of papillary proliferations of atypical serous epithelial cells and a cystic component.  There is no evidence of stromal invasion.


NRAS Exon 2 Mutation Negative

description: A genetic finding indicating that NRAS exon 2 gene mutations have not been detected in a sample.


Vaginal Perforation, CTCAE 5.0

description: A disorder characterized by a rupture in the vaginal wall.


name: Memory Deficit following Unspecified Cerebrovascular Disease

description: Evidence of memory deficit following unspecified cerebrovascular disease.


Digestive System Cancer TNM Finding v7

description: A finding about one or more characteristics of digestive system cancer, following the rules of the TNM AJCC v7 classification system.


name: Grade 3 Upper Extremity Vein Intra-Operative Injury, CTCAE


Unresectable Malignant Gastric Neoplasm

description: A malignant gastric neoplasm that is not amenable to surgical resection.


Reiter's disease, multiple sites

description: Evidence of Reiter's disease in multiple sites.


Pain of Skin, CTCAE

description: A disorder characterized by a sensation of marked discomfort in the skin.


name: Grade 3 Eye NOS Intra-Operative Injury, CTCAE


name: Grade 3 Intraoperative Head and Neck Injury, CTCAE

description: Complete resection or reconstruction of injured organ/structure indicated; limiting self care ADL


HIV Serology Test Result

description: The outcome of human immunodeficiency virus serology testing.


Bidirectional HLA Mismatch

description: The state when a recipient of a hematopoietic stem cell transplantation is not fully matched with their unrelated adult volunteer donor for HLA-A, HLA-B, HLA-C, and HLA-DRB1 and both are heterozygous for different alleles at one locus.


name: Gastrointestinal Stromal Tumor pM1 TNM Finding v8

description: Gastrointestinal stromal tumor with distant metastasis. (from AJCC 8th Ed.)


name: Colorectal Cancer Clinical TNM Finding v8

description: A clinical finding about one or more characteristics of colorectal cancer, following the rules of the TNM AJCC v8 classification system.


name: Grade 1 Non-Malignant Pleural Effusion, CTCAE


Grade 3 Oral Hemorrhage, CTCAE

description: Transfusion indicated; invasive intervention indicated; hospitalization


Grade 4 Splenic Infection, CTCAE

description: Life-threatening consequences; urgent intervention indicated


name: Invasive Bladder Urothelial Carcinoma with Trophoblastic Differentiation

description: An invasive bladder urothelial carcinoma characterized by the presence of trophoblastic differentiation.


Metastatic NUT Carcinoma

description: NUT carcinoma that has spread from its original site of growth to another anatomic site.


Peritoneal Sarcomatosis

description: A condition in which a sarcoma has spread extensively throughout the peritoneum.


Vaginal Infection, CTCAE

description: A disorder characterized by an infectious process involving the vagina.


name: Grade 3 Biliary Tree Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


name: Grade 5 Salivary Gland Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


Hemolysis, CTCAE

description: A disorder characterized by laboratory test results that indicate widespread erythrocyte cell membrane destruction.


Melanoma in situ of trunk

description: Evidence of melanoma in situ of trunk.


Grade 5 Ileal Fistula, CTCAE

description: Death


Infective cystitis

description: An infectious process affecting the urinary bladder.


name: Carcinoma of the Eyelid cN1 TNM Finding v7

description: Carcinoma of the eyelid with regional lymph node metastasis. (from AJCC 7th Ed.)


name: Merkel Cell Carcinoma cN1 TNM Finding v8

description: Merkel cell carcinoma with metastasis in regional lymph node(s). (from AJCC 8th Ed.)


name: Grade 2 Cranial Nerve IX Neuropathy, CTCAE


Diffuse Midline Glioma, H3 K27-Altered

description: A diffuse midline glioma characterized by H3 K27 alteration and usually either a histone H3 K27M mutation, an EGFR mutation, or aberrant overexpression of EZHIP. The prognosis is poor.


FCER2 Negative

description: Indicates that expression of FCER2 has not been detected in a sample.


Refractory WHO Grade 2 Glioma

description: WHO grade 2 glioma that is resistant to treatment.


name: Grade 5 Upper Aerodigestive Infection NOS Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


name: Grade 3 Cecum Intra-Operative Injury, CTCAE


name: Metastatic Bladder Plasmacytoid Urothelial Carcinoma

description: Bladder plasmacytoid urothelial carcinoma that has spread to another anatomic site.


Grade 2 Gait Disturbance, CTCAE

description: Moderate change in gait (e.g., wide-based, limping or hobbling); assistive device indicated; limiting instrumental ADL


name: IgM Monoclonal Gammopathy of Undetermined Significance, Plasma Cell Type

description: A subtype of IgM monoclonal gammopathy of undetermined significance characterized by the presence of clonal plasma cells, absence of clonal B-lymphocytes, and absence of MYD88 gene mutation. The t(11;14)(q13;q32) is present in some cases. This subtype is considered a precursor of multiple myeloma.


Bone Cancer pT0 TNM Finding v7

description: Bone cancer with no evidence of primary tumor. (from AJCC 7th Ed.)


name: Chronic gastric ulcer without hemorrhage AND without perforation

description: Evidence of chronic gastric ulcer without hemorrhage or perforation.


Symptomatic Presentation

description: A clinical description in which a patient demonstrates evidence of more than one clinical finding suggestive of underlying pathology. (ACC/AHA)


Head and Neck Cancer TNM Finding v6

description: A finding about one or more characteristics of head and neck cancer, following the rules of the TNM AJCC v6 classification system.


name: Distal Bile Duct Cancer Clinical Distant Metastasis TNM Finding v8

description: A clinical finding about one or more characteristics of distal bile duct cancer, following the rules of the TNM AJCC v8 classification system as they pertain to distant metastases.


Small Intestine Ulcer, CTCAE

description: A disorder characterized by a circumscribed, erosive lesion on the mucosal surface of the small intestine.


name: Unresectable Digestive System Neuroendocrine Carcinoma

description: A neuroendocrine carcinoma that arises from any part of the digestive system and is not amenable to surgical resection.


name: Grade 2 Penis Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


name: Chest Pain in Right Second Intercostal Space

description: The location of the chest pain is within the second intercostal space on the right side.


Non-Neoplastic Mediastinal Disorder

description: A non-neoplastic disorder that affects the structures of the mediastinum.  Representative examples include mediastinitis and thymic hyperplasia.


Grade 5 Hyperthyroidism, CTCAE

description: Death


name: Conjunctival Melanoma cT3 TNM Finding v8

description: Conjunctival melanoma with tumor of any size with local invasion. (from AJCC 8th Ed.)


name: Fallopian Tube Cancer pT1 TNM Finding v7

description: Fallopian tube cancer limited to fallopian tube(s). (from AJCC 7th Ed.)


name: Major Salivary Gland Cancer Clinical Regional Lymph Nodes TNM Finding v8

description: A clinical finding about one or more characteristics of major salivary gland cancer, following the rules of the TNM AJCC v8 classification system as they pertain to staging of regional lymph nodes.


name: Grade 4 Left Ventricular Systolic Dysfunction, CTCAE

description: Refractory or poorly controlled heart failure due to drop in ejection fraction; intervention such as ventricular assist device, intravenous vasopressor support, or heart transplant indicated


name: Grade 1 Fibrosis-Deep Connective Tissue, CTCAE


name: Undescribed Disease Entity Reported to CTRP

description: A designation used to map diseases reported by clinical trial sites to CTRP that have not been described in the medical literature.


alcoholic hepatic failure with coma

description: Evidence of alcoholic hepatic failure with coma.


Grade 5 Hypocalcemia, CTCAE

description: Death


Grade 3 Tremor, CTCAE

description: Severe symptoms; limiting self care ADL


Chills, CTCAE

description: A disorder characterized by a sensation of cold that often marks a physiologic response to sweating after a fever.


Jaccoud Arthropathy, Left Hand

description: Evidence of Jaccoud arthropathy in the left hand.


Hair Color Changes, CTCAE

description: A disorder characterized by change in hair color or loss of normal pigmentation.


name: Pre-Existing Secondary Hypertension Complicating Childbirth

description: Evidence of pre-existing secondary hypertension complicating childbirth.


Cytomegalovirus gastroenteritis

description: Gastroenteritis resulting from an infection with cytomegalovirus.


Childhood Digestive System Neoplasm

description: A neoplasm that affects any part of the digestive system and occurs during childhood.


Mixed Trophoblastic Tumor

description: A gestational trophoblastic tumor characterized by the presence of two or three histological types of gestational trophoblastic tumor, including choriocarcinoma, placental site trophoblastic tumor, and epithelioid trophoblastic tumor.


name: Grade 3 Infertility and Sterility, CTCAE


Stage 0 Gallbladder Cancer AJCC v8

description: Stage 0 includes: Tis, N0, M0. Tis: Carcinoma in situ. N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 8th ed.)


name: Neuropathy, Recurrent, with Pressure Palsies

description: An autosomal dominant condition caused by mutation(s) in the PMP22 gene, encoding peripheral myelin protein 22. Neuropathy is precipitated by mechanical compression on a nerve, typically with onset in the first and second decades.


name: Grade 4 Upper Extremity Artery Injury, CTCAE


name: Grade 4 Wound Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


Other Drug-Induced Dystonia

description: Evidence of other drug-induced dystonia not specified elsewhere.


Grade 5 Vomiting, CTCAE

description: Death


Stage III Merkel Cell Carcinoma AJCC v7

description: Stage III includes: IIIA: (Any T, N1a, M0) and IIIB: (Any T, N1b/N2, M0).  N1a: Micrometastasis in regional lymph nodes.  N1b: Macrometastasis in regional lymph nodes.  N2: In transit metastasis.  M0: No distant metastasis.  (AJCC 7th Ed.)


Stage IIA Gallbladder Cancer AJCC v8

description: Stage IIA includes: T2a, N0, M0. T2a: Tumor invading the perimuscular connective tissue on the peritoneal side, without involvement of the serosa (visceral peritoneum). N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 8th ed.)


name: Grade 5 Infections and Infestations - Other, Specify, CTCAE

description: Death


name: Maxillary Sinus Cancer Clinical Distant Metastasis TNM Finding v7

description: A clinical finding about one or more characteristics of maxillary sinus cancer, following the rules of the TNM AJCC v7 classification system as they pertain to distant metastases.


Fibrohistiocytic Neoplasm

description: A benign, intermediate, or malignant mesenchymal neoplasm composed of fibrohistiocytic cells, spindle fibroblastic cells, and histiocytes, in a storiform pattern.


name: Grade 1 Injury, Poisoning and Procedural Complications - Other, Specify, CTCAE

description: Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated


name: Perihilar Bile Duct Cancer Pathologic Distant Metastasis TNM Finding v8

description: A pathologic finding about one or more characteristics of perihilar bile duct cancer, following the rules of the TNM AJCC v8 classification system as they pertain to distant metastases.


name: Grade 3 Skin Intra-Operative Injury, CTCAE


Stage IIB Cervical Cancer AJCC v9

description: Stage IIB includes: T2b, N0, M0. T2b: Tumor with parametrial invasion but not up to the pelvic wall. N0: No regional lymph node metastasis. M0: No distant metastasis. (from AJCC 9th Ed.)


name: Rheumatoid Nodule, Unspecified Ankle and Foot

description: Evidence of rheumatoid nodule in an unspecified ankle and foot.


Unresectable Sarcoma

description: A sarcoma which is not amenable to surgical resection.


name: Carcinoma of the Conjunctiva pT0 TNM Finding v7

description: Carcinoma of the conjunctiva with no evidence of a primary tumor. (from AJCC 7th Ed.)


name: Conjunctival Melanoma pT2 TNM Finding v8

description: Conjunctival melanoma with tumor of the nonbulbar (forniceal, palpebral, tarsal) conjunctiva, and tumor involving the caruncle. (from AJCC 8th Ed.)


Grade 3 Hepatic Infection, CTCAE

description: IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated


name: Appendicular Skeleton, Trunk, Skull, and Facial Bones Cancer Pathologic Primary Tumor TNM Finding v8

description: A pathologic finding about one or more characteristics of appendicular skeleton, trunk, skull, and facial bones cancer, following the rules of the TNM AJCC v8 classification system as they pertain to staging of the primary tumor.


Home-related Exposure

description: Exposure to potentially harmful chemical, physical, or biological agents in the home.


Syphilis of Liver and Other Viscera

description: Evidence of syphilis of liver and other viscera.


Decreased NCF1 Expression

description: An indication that the expression of NCF1 is lower than the normal range of values.


name: Stage II Gestational Trophoblastic Neoplasm AJCC v8

description: Stage II includes: T2, M0. T2: Gestational trophoblastic neoplasm in which the tumor extends to other genital structures (ovary, tube, vagina, broad ligaments) by metastasis or direct extension. M0: No distant metastasis. (AJCC 8th Ed.)


Fibromuscular Stroma of Prostate

description: The portion of the prostate comprising both fibrous and muscle tissue that fills the spaces between the glandular tissue.


Grade 4 Infant Irritability, AE

description: An adverse event in a newborn characterized by life threatening irritability, with loss of autonomic control of temperature or heart rate; requiring urgent care change.


name: Other specified malignant neoplasm of skin of right upper eyelid, including canthus

description: Evidence of other specified malignant neoplasm of skin of right upper eyelid including the canthus not specified elsewhere.


name: Oropharyngeal (p16-Negative) Cancer Clinical Regional Lymph Nodes TNM Finding v8

description: A clinical finding about one or more characteristics of oropharyngeal (p16-negative) cancer, following the rules of the TNM AJCC v8 classification system as they pertain to staging of regional lymph nodes.


name: Other Psychoactive Substance Dependence with Mood Disorder

description: Evidence of other psychoactive substance dependence with mood disorder not specified elsewhere.


Prostate Cancer pT4 TNM Finding v8

description: Prostate cancer in which the tumor is fixed or invades adjacent structures other than seminal vesicles such as external sphincter, rectum, bladder, levator muscles, and/or pelvic wall. (from AJCC 8th Ed.)


Cervical Cancer pN0 TNM Finding v9

description: Cervical cancer with no regional lymph node metastasis. (from AJCC 9th Ed.)


name: Soft Tissue Sarcoma of the Abdomen and Thoracic Visceral Organs pT4a TNM Finding v8

description: Soft tissue sarcoma of the abdomen and thoracic visceral organs with multifocal involvement (two sites). (from AJCC 8th Ed.)


name: Smoldering Systemic Mastocytosis with an Associated Myeloid Neoplasm

description: Smoldering systemic mastocytosis associated with the presence of a clonal non-mast cell myeloid neoplasm (e.g., myelodysplastic syndrome,  myeloproliferative neoplasm, and acute myeloid leukemia).


name: Human papillomavirus negative squamous cell carcinoma

description: A squamous cell carcinoma not associated with human papilloma virus infection.


Stage II Cervical Cancer AJCC v6

description: Stage II includes: II (T2, N0, M0); IIA (T2a, N0, M0); IIB (T2b, N0, M0). T2: Cervical carcinoma invades beyond uterus but not to pelvic wall or to lower third of vagina. T2a: Tumor without parametrial invasion. T2b: Tumor with parametrial invasion.  N0: No regional lymph node metastasis.  M0: No distant metastasis. (AJCC 6th ed.)


name: Grade 3 Small Intestinal Perforation, CTCAE

description: Invasive intervention indicated


Gallbladder Cancer TNM Finding v6

description: A finding about one or more characteristics of primary gallbladder cancer, following the rules of the TNM AJCC v6 classification system.


name: Grade 2 Cranial Nerve IV Neuropathy, CTCAE


name: Grade 3 Scrotum Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


Grade 2 Jejunal Hemorrhage, CTCAE

description: Moderate symptoms; intervention indicated


Lung Cancer pT1b TNM Finding v7

description: Lung cancer with a tumor size more than 2 cm but 3 cm or less in greatest dimension, surrounded by lung or visceral pleura and without bronchoscopic evidence of invasion more proximal than the lobar bronchus (i.e., not in the main bronchus). The uncommon superficial tumor of any size with its invasive component limited to the bronchial wall, which may extend proximal to the main bronchus, is also classified as T1a. (from AJCC 7th Ed.)


Recurrent Anal Mucinous Adenocarcinoma

description: The reemergence of anal mucinous adenocarcinoma after a period of remission.


name: Colorectal Neuroendocrine Tumor Pathologic Primary Tumor TNM Finding v8

description: A pathologic finding about one or more characteristics of a colorectal neuroendocrine tumor, following the rules of the TNM AJCC v8 classification system as they pertain to staging of the primary tumor.


Prostate Cancer by AJCC v7 Stage

description: A term that refers to the staging of prostate carcinoma according to the American Joint Committee on Cancer, 7th edition.


name: Gastric Neuroendocrine Tumor pT3 TNM Finding v7

description: Gastric neuroendocrine tumor penetrating subserosa.  (from AJCC 7th Ed.)


name: Merkel Cell Carcinoma Pathologic Distant Metastasis TNM Finding v8

description: A pathologic finding about one or more characteristics of Merkel cell carcinoma, following the rules of the TNM AJCC v8 classification system as they pertain to distant metastases.


PALB2-Associated Malignant Neoplasm

description: A malignant neoplasm caused by deleterious germline mutation in the PALB2 gene. This mutation is associated with the development of breast carcinoma and pancreatic carcinoma.


Maternal Proteinuria

description: The presence of excessive protein, chiefly albumin but also globulin, in the urine of a pregnant woman.


name: Bladder Cancer Pathologic Distant Metastasis TNM Finding v7

description: A pathologic finding about one or more characteristics of bladder cancer, following the rules of the TNM AJCC v7 classification system as they pertain to distant metastases.  There is no pathologic M0 for bladder cancer. (from AJCC 7th Ed.)


Grade 1 Renal Hemorrhage, CTCAE

description: Mild symptoms; intervention not indicated


name: Esophagus and Esophagogastric Junction Cancer pTis TNM Finding v8

description: Esophagus and esophagogastric junction cancer with a finding of high-grade dysplasia, defined as malignant cells confined to the epithelium by the basement membrane. (from AJCC 8th Ed.)


Liver Neuroendocrine Tumor G1

description: A well differentiated, low grade neoplasm with neuroendocrine differentiation that arises from the liver. The mitotic count is less than 2 per 10 HPF.


Rare Malignant Solid Neoplasm

description: A malignant solid neoplasm with an annual incidence of less than 6 per 100,000 people.


description: Evidence of cocaine abuse with intoxication with delirium.


name: Pancreatic Moderately Differentiated Ductal Adenocarcinoma

description: A pancreatic ductal adenocarcinoma characterized by the presence of medium-sized duct-like structures and small malignant tubular glandular structures.


name: Steroid-Dependent Gastrointestinal Tract Acute Graft Versus Host Disease

description: Gastrointestinal tract acute graft versus host disease that is responsive to treatment with steroids but relapses during attempts at tapering or discontinuing steroid therapy.


Grade 3 Tumor Hemorrhage, CTCAE

description: Transfusion indicated; invasive intervention indicated; hospitalization


name: Cervix Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


Paresthesia, CTCAE

description: A disorder characterized by functional disturbances of sensory neurons resulting in abnormal cutaneous sensations of tingling, numbness, pressure, cold, and/or warmth.


Grade 1 Neonatal Convulsion, AE

description: An adverse event in a newborn characterized by a single, self-limited suspected seizure requiring no treatment.


name: Unspecified Atherosclerosis of Native Arteries of Extremities, Unspecified Extremity

description: Evidence of unspecified atherosclerosis of native arteries of extremities in an unspecified extremity.


name: Grade 2 Gastroesophageal Reflux Disease, CTCAE

description: Moderate symptoms; medical intervention indicated


name: Drug or Chemical Induced Diabetes Mellitus with Severe Non-Proliferative Diabetic Retinopathy without Macular Edema, Right Eye

description: Evidence of drug or chemical induced diabetes mellitus with severe non-proliferative diabetic retinopathy without macular edema in the right eye.


Grade 3 Hypercalcemia, CTCAE

description: Corrected serum calcium of >12.5-13.5 mg/dL; >3.1-3.4 mmol/L; Ionized calcium >1.6-1.8 mmol/L; hospitalization indicated


name: Carcinoma in Situ of Gingiva and Edentulous Alveolar Ridge

description: Evidence of carcinoma in situ of the gingiva and edentulous alveolar ridge.


name: Type 2 Diabetes Mellitus with Mild Nonproliferative Diabetic Retinopathy with Macular Edema, Left Eye

description: Evidence of type 2 diabetes mellitus with mild nonproliferative diabetic retinopathy with macular edema in the left eye.


Esophageal Cancer by AJCC v7 Stage

description: A term that refers to the staging of esophageal carcinoma according to the American Joint Committee on Cancer, 7th edition.


name: Carcinoma of the Eyelid cM0 TNM Finding v7

description: Carcinoma of the eyelid without evidence of distant metastasis. (from AJCC 7th Ed.)


name: PSA Level Twenty to One Hundred Fifty or Greater

description: A blood concentration of prostate specific antigen between 20 ng/mL and 150 ng/mL or greater.


Grade 5 Uterine Hemorrhage, CTCAE

description: Death


name: Personality and Behavioral Change, CTCAE


Type I Endometrial Adenocarcinoma

description: A classification of primary endometrial adenocarcinomas that refers to endometrioid adenocarcinoma and mucinous adenocarcinoma.


name: Grade 4 Carotid Artery Intra-Operative Injury, CTCAE


Antimicrobial Resistance Result

description: A microbial susceptibility test result in which the growth of microorganisms is not inhibited by the usually achievable concentrations of antimicrobial agent with normal dosage, or microorganisms demonstrate minimum inhibitory concentrations (MIC) or zone diameters that fall in the range where specific microbial resistance mechanisms are likely in effect, or clinical efficacy of the agent against the microorganism has not been reliably shown in treatment studies.


Stage 0 Vulvar Cancer AJCC v6

description: Stage 0 includes: Tis, N0, M0.  Tis: Carcinoma in situ (preinvasive carcinoma. N0: No regional lymph node metastasis.  M0: No distant metastasis. (AJCC 6th ed.)


Low Grade Endometrioid Adenocarcinoma

description: Endometrioid adenocarcinoma exhibiting 50% or less solid non-glandular, non-squamous growth.


Retention cyst

description: A cyst that is formed because of the blockage of the duct of a glandular organ. This results in the retention of the glandular secretions.


name: Melanoma of the Uvea cM1b TNM Finding v7

description: Melanoma of the uvea with distant metastasis, with the largest diameter of the largest metastasis measuring 3.1-8.0 cm. (from AJCC 7th Ed.)


Grade 1 Colonic Ulcer, CTCAE

description: Asymptomatic; clinical or diagnostic observations only; intervention not indicated


name: Hemolytic disease of fetus OR newborn due to ABO immunization

description: A condition of the newborn characterized by the destruction of red blood cells initiated by the transmission of anti-A or anti-B antibodies from a mother to the child via the placenta against A or B antigens of the newborn's blood.


name: Pancreas Exocrine Enzyme Deficiency, CTCAE


name: Lymphoid Leukemia, Unspecified not Having Achieved Remission

description: Evidence of lymphoid leukemia, unspecified not having achieved remission.


name: Prostate Carcinoma Metastatic in the Soft Tissue

description: A carcinoma that arises from the prostate gland and has spread to the soft tissues.


PSA Doubling Time Less than 12 Months

description: An indication that the number of months that a subject's blood concentration of prostate specific antigen took to double was less than twelve months.


Bladder Cancer pT0 TNM Finding v8

description: Bladder cancer with no evidence of primary tumor. (from AJCC 8th Ed.)


name: Grade 2 Small Bowel Mucositis or Stomatitis by Clinical Examination Classification, CTCAE


name: Postneoadjuvant Therapy Stage IIIA Esophageal Adenocarcinoma AJCC v8

description: Stage IIIA includes: T0-2, N1, M0. T0: No evidence of primary tumor. T1: Tumor invades the lamina propria, muscularis mucosae, or submucosa. T2: Tumor invades the muscularis propria. N1: Tumor with metastasis in one or two regional lymph nodes. M0: No distant metastasis. (AJCC 8th ed.)


Laryngeal Cancer TNM Finding v6

description: A finding about one or more characteristics of laryngeal cancer, following the rules of the TNM AJCC v6 classification system.


PSA Level Greater than or Equal to 0.5

description: A blood concentration of prostate specific antigen greater than or equal to 0.5 ng/mL.


name: Rheumatoid Vasculitis with Rheumatoid Arthritis of Unspecified Knee

description: Evidence of rheumatoid vasculitis with rheumatoid arthritis of unspecified knee.


Grade 1 Hyperphosphatemia, CTCAE

description: Laboratory finding only and intervention not indicated


name: Death Not Associated with More Specific Term NOS, CTCAE


Grade 3 Wound Complication, CTCAE

description: Operative intervention indicated


Fifth Relapse

description: The reemergence of a disorder as diagnosed by clinical and/or laboratory evidence following five documented periods of remission.


name: Metastatic malignant neoplasm to viscera

description: A malignant neoplasm which has spread from its original site of growth to any visceral site.


name: Rheumatoid Arthritis with Rheumatoid Factor of Unspecified Site without Organ or Systems Involvement

description: Evidence of rheumatoid arthritis with rheumatoid factor of unspecified site without organ or systems involvement.


Normal Abdomen on Palpation

description: An indication that palpation of the abdomen demonstrates no organomegaly or masses found.


name: Grade 2 Non-Infectious Wound Complication, CTCAE


Breast Cancer pN3b TNM Finding v6

description: Breast cancer with metastasis in clinically apparent ipsilateral internal mammary lymph nodes in the presence of 1 or more positive axillary lymph nodes; or in more than 3 axillary lymph nodes and in internal mammary lymph nodes with microscopic disease detected by sentinel lymph node dissection but not clinically apparent. (from AJCC 6th Ed.)


Grade 1 Pulmonary Fibrosis, CTCAE

description: Radiologic pulmonary fibrosis <25% of lung volume associated with hypoxia


name: Monoplegia of Upper Limb following Cerebral Infarction Affecting Right Dominant Side

description: Evidence of monoplegia of upper limb following cerebral infarction affecting right dominant side.


Tracheal Obstruction, CTCAE

description: A disorder characterized by blockage of the lumen of the trachea.


name: Cytogenetically normal acute myeloid leukemia

description: Acute myeloid leukemia not associated with cytogenetic abnormalities.


Adenocarcinoma in tubulovillous adenoma

description: A non-invasive or invasive adenocarcinoma arising from a tubulovillous adenoma.


Iron deficiency

description: Subnormal concentrations of iron resulting from low iron intake, inefficient iron absorption in the gastrointestinal tract, or increased iron loss.


name: Conjunctival Carcinoma pT4c TNM Finding v8

description: Conjunctival carcinoma with tumor invading adjacent paranasal sinuses. (from AJCC 8th Ed.)


Butyrate Level Finding

description: A finding that indicates the amount of butyrate, which includes any salt or ester forms of the short chain fatty acid butyric acid, in a sample.


Grade 4 Tracheal Obstruction, CTCAE

description: Life-threatening airway compromise; urgent intervention indicated (e.g., tracheotomy or intubation)


Perinatal cyanotic attacks

description: Episodes of cyanosis during the perinatal period.


Orthokeratinized odontogenic cyst

description: An odontogenic cyst that is entirely or predominantly lined by orthokeratinized stratified squamous epithelium. (WHO 2017)


Breast Solid Neuroendocrine Carcinoma

description: A neuroendocrine carcinoma that arises from the breast.  It is characterized by the presence of cellular solid nests and trabeculae that contain spindle-shaped, plasmacytoid, and large neuroendocrine cells.


name: Grade 1 Tracheostomy Site Bleeding, CTCAE

description: Minimal bleeding identified on clinical exam; intervention not indicated


Grade 3 Facial Nerve Disorder, CTCAE

description: Severe symptoms; limiting self care ADL


name: Grade 3 Skin Infection with Unknown Absolute Neutrophil Count, CTCAE


Primary Meningeal Melanocytic Neoplasm

description: A melanocytic neoplasm that arises from the leptomeninges. This category includes diffuse proliferative processes (melanocytosis and melanomatosis) and circumscribed processes (melanocytoma and melanoma).


Breast Cancer pN2 TNM Finding v7

description: Breast cancer with metastases in 4 to 9 axillary lymph nodes, or metastases in clinically detected internal mammary lymph nodes in the absence of axillary lymph node metastases.  "Clinically detected" is defined as detected by imaging studies (excluding lymphoscintigraphy) or by clinical examination and having characteristics highly suspicious for malignancy or a presumed pathologic macrometastasis based on fine needle aspiration biopsy with cytologic examination. (from AJCC 7th Ed.)


name: Lugano Classification Stage IV Hodgkin Lymphoma AJCC v8

description: Stage IV: Diffuse or disseminated involvement of one or more extralymphatic organs, with or without associated lymph node involvement; or noncontiguous extralymphatic organ involvement in conjunction with nodal stage II disease; or any extralymphatic organ involvement in nodal stage III disease. Stage IV includes any involvement of the CSF, bone marrow, liver, or lungs (other than by direct extension in stage IIE disease). (from AJCC 8th Ed.)


name: Nasal Cavity and Paranasal Sinuses Cancer pM1 TNM Finding v8

description: Nasal cavity and paranasal sinuses cancer with distant metastasis. (from AJCC 8th Ed.)


Gastric infection

description: An acute or chronic infectious process affecting the stomach.


PSA Level Less than One

description: A blood concentration of prostate specific antigen less than 1 ng/mL.


name: Atherosclerosis of Non-Biological Bypass Graft(s) of the Left Leg with Ulceration of Unspecified Site

description: Evidence of atherosclerosis of non-biological bypass graft(s) of the left leg with ulceration of unspecified site.


Grade 3 Edema Trunk, CTCAE

description: Gross deviation from normal anatomic contour; limiting self care ADL


Breast Cancer cN2a TNM Finding v8

description: Breast cancer with metastases in ipsilateral level I, II axillary lymph nodes fixed to one another (matted) or to other structures. (from AJCC 8th Ed.)


name: Systemic sclerosis induced by drugs and chemicals

description: Evidence of systemic sclerosis induced by drug and chemical.


name: Carbon Monoxide Diffusing Capacity Decreased, CTCAE

description: A finding based on lung function test results that indicate a decrease in the lung capacity to absorb carbon monoxide.


name: Grade 4 Cranial Nerve I Neuropathy, CTCAE


Negative Skin Test

description: A finding that indicates the absence of an immune response to an antigen that is introduced to the skin.


Anal Inflammatory Cloacogenic Polyp

description: A non-neoplastic polypoid lesion that arises from the anal transitional zone.  It is characterized by the presence of hyperplastic rectal mucosa that is partially covered by squamous or transitional epithelium.


name: Grade 4 Catheter-Related Infection with Unknown Absolute Neutrophil Count, CTCAE


name: Grade 5 Hypoxic Ischemic Encephalopathy, AE

description: An hypoxic ischemic encephalopathy adverse event in a newborn which results in death.


name: Peritoneal and retroperitoneal disorders

description: A non-neoplastic or neoplastic disorder that affects the peritoneum and/or retroperitoneum.


Grade 3 Obesity, CTCAE

description: BMI 30-39.9 kg/m2


RAS/BRAF/NF1 Triple Wild Type

description: A genetic finding indicating that mutations in BRAF, NF1 and RAS family genes have not been detected in a sample.


Stage IIB Cervical Cancer AJCC v8

description: Stage IIB includes: T2b, Any N, M0. T2b: Cervical carcinoma invading beyond the uterus but not to the pelvic wall or to lower third of vagina with parametrial invasion. M0: No distant metastasis. (AJCC 8th Ed.)


name: Life Threatening or Disabling Adverse Event

description: Any adverse event that places the patient, in the view of the initial reporter, at immediate risk of death from the adverse event as it occurred, i.e., it does not include an adverse experience that, had it occurred in a more severe form, might have caused death.


Other folate deficiency anemias

description: Evidence of other folate deficiency anemias not specified elsewhere.


Subglottic Cancer pT4a TNM Finding v6

description: Subglottic cancer with tumor invading cricoid or thyroid cartilage and/or invading tissues behind the larynx (e.g. trachea, soft tissues of neck including deep extrinsic muscles of the tongue, strap muscles, thyroid, or esophagus). (from AJCC 6th Ed.)


Single Ventricle Defect

description: A diverse group of congenital cardiovascular abnormalities that share one characteristic, the presence of a single functional cardiac ventricle.


name: Grade 4 Retroperitoneal Hemorrhage, CTCAE

description: Life-threatening consequences; urgent intervention indicated


name: Pleural Malignant Mesothelioma pT3 TNM Finding v8

description: Pleural malignant mesothelioma in which the tumor is locally advanced but potentially resectable. The tumor involves all the ipsilateral pleural surfaces (parietal, mediastinal, diaphragmatic, and visceral pleura) with at least one of the following features: involvement of the endothoracic fascia, extension into the mediastinal fat, solitary, completely resectable focus of tumor extending into the soft tissues of the chest wall, and/or nontransmural involvement of the pericardium. (from AJCC 8th Ed.)


name: Non-Neoplastic Digestive System Disorder

description: A non-neoplastic disorder that affects the gastrointestinal tract, anus, liver, biliary system, and pancreas. Representative examples include infections, ulcers, cirrhosis, and diverticulosis.


Urethral Cancer pTa TNM Finding v7

description: Urethral cancer with a finding of noninvasive papillary, polypoid, or verrucous carcinoma. (from AJCC 7th Ed.)


Merkel cell carcinoma of skin of breast

description: Evidence of Merkel cell carcinoma of skin of breast.


name: Primary Cutaneous B-Cell/T-Cell (Non-MF/SS) Lymphoma N3 TNM Finding v8

description: Involvement of central lymph nodes. (from AJCC 8th Ed.)


name: Grade 4 Neutrophils and Granulocytes, CTCAE


Somatic Variation Rate

description: The frequency of mutations in a sample derived from non-germline cells or tissues.


Pancreas Infection, CTCAE

description: A disorder characterized by an infectious process involving the pancreas.


name: Grade 3 Heart Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


name: Colorectal Neuroendocrine Tumor TNM Finding v8

description: A finding about one or more characteristics of a colorectal neuroendocrine tumor, following the rules of the TNM AJCC v8 classification system. This classification system applies to colorectal "carcinoid" tumors (neuroendocrine tumor G1 and G2, and rare-well differentiated G3). It does not apply to high-grade neuroendocrine carcinomas and mixed adenoneuroendocrine carcinomas of the colon and rectum. (from AJCC 8th Ed.)


Grade 1 Hepatitis B Reactivation, CTCAE

description: Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated


name: Grade 2 Vaginal Stenosis and Length, CTCAE


pTa TNM Finding

description: A term that refers to a TNM finding of a primary, non-invasive, papillary cancer.


Second Primary Tumor

description: A new primary neoplasm that occurs in a person who was previously diagnosed with another primary neoplasm.


name: Infiltrating Ureter Urothelial Carcinoma with Mixed Differentiation


Metastatic non-small cell carcinoma

description: Non-small cell carcinoma that has spread from its original site of growth to another anatomic site.


name: Melanoma of the Conjunctiva pT2c TNM Finding v7

description: Melanoma of the palpebral, forniceal, or caruncular conjunctiva with tumor measuring more than 1.5 mm in thickness with invasion of the substantia propria.  (from AJCC 7th Ed.)


Lichenoid drug eruption

description: A red or violaceous flat-topped, papular eruption that is induced by exposure to a variety of medications or environmental agents.


Malignant Visual Pathway Neoplasm

description: A primary or metastatic malignant neoplasm that affects the visual pathway.


Grade 3 Dermatitis Radiation, CTCAE

description: Moist desquamation in areas other than skin folds and creases; bleeding induced by minor trauma or abrasion


Grade 4 Jejunal Ulcer, CTCAE

description: Life-threatening consequences; urgent operative intervention indicated


Metastatic Ampulla of Vater Carcinoma

description: Carcinoma that arises from the ampulla of Vater and has spread to another anatomic site.


name: Grade 4 Lung Thoracic Nerve Intra-Operative Injury, CTCAE


name: Other Psychoactive Substance Dependence with Unspecified Disorder

description: Evidence of other psychoactive substance dependence with unspecified disorder not specified elsewhere.


Grade 2 Cervicitis Infection, CTCAE

description: Localized; local intervention indicated (e.g., topical antibiotic, antifungal, or antiviral)


Retinoblastoma pN0 TNM Finding v7

description: Retinoblastoma with no regional lymph node involvement. (from AJCC 7th Ed.)


Firearm Injury

description: An injury sustained by a gun.


Uterine Corpus Cancer TNM Finding v7

description: A finding about one or more characteristics of uterine corpus cancer, following the rules of the TNM AJCC v7 classification system.  The TNM findings for uterine corpus carcinomas and sarcomas are not the same. (from AJCC 7th Ed.)


Sternotomy Scar

description: Replacement of destroyed tissue by fibrous tissue due to a surgical procedure where a vertical inline incision is made along the sternum, after which the sternum itself is divided. (ACC/AHA)


name: Malignant melanoma of left lower eyelid, including canthus

description: Evidence of a malignant melanoma of the left lower eyelid including the canthus.


name: Grade 5 Meninges Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


name: Grade 4 Outer Ear NOS Intra-Operative Injury, CTCAE


name: Refractory Histiocytic and Dendritic Cell Neoplasm

description: A histiocytic and dendritic cell neoplasm that does not respond to treatment.


Stage IIC Merkel Cell Carcinoma AJCC v7

description: Stage IIC includes: T4, N0, M0.  T4: Primary tumor invades bone, muscle, fascia, or cartilage.  N0: No regional lymph node metastasis.  M0: No distant metastasis.  (AJCC 7th Ed.)


Nail Matrix Nevus

description: An acral nevus that arises from the nail matrix.


name: Intrahepatic Bile Duct Cancer cM0 TNM Finding v8

description: Intrahepatic bile duct cancer without evidence of distant metastasis. (from AJCC 8th Ed.)


Myeloid Neoplasm with Mutated TP53

description: Myeloid neoplasm characterized by the presence of TP53 gene mutations. This category includes myelodysplastic syndrome, myelodysplastic syndrome/acute myeloid leukemia, and acute myeloid leukemia with mutated TP53.


Urethral Cancer pN1 TNM Finding v8

description: Urethral cancer with single regional lymph node metastasis in the inguinal region or true pelvis [perivesical, obturator, internal (hypogastric) and external iliac], or presacral lymph node. (from AJCC 8th Ed.)


name: Rheumatoid Myopathy with Rheumatoid Arthritis of Unspecified Ankle and Foot

description: Evidence of rheumatoid myopathy with rheumatoid arthritis of unspecified ankle and foot.


name: Grade 1 Larynx Mucositis or Stomatitis by Clinical Examination Classification, CTCAE


name: Localization-Related Idiopathic Epilepsy and Epileptic Syndromes with Seizures of Localized Onset, not Intractable, with Status Epilepticus

description: Evidence of localization-related idiopathic epilepsy and epileptic syndromes with seizures of localized onset with status epilepticus that responds to treatment.


name: Diabetes Mellitus due to Underlying Condition with Foot Ulcer

description: Evidence of diabetes mellitus due to underlying condition with foot ulcer.


name: Testicular Cancer Serum Markers Test Result

description: A laboratory test result in which markers for testicular cancer are tested in a blood sample for staging purposes.


Pelvis Cancer pT0 TNM Finding v8

description: Pelvis cancer without evidence of primary tumor. (from AJCC 8th Ed.)


Lung Cancer pTX TNM Finding v8

description: Lung cancer in which the primary tumor cannot be assessed. (from AJCC 8th Ed.)


name: Atherosclerosis of Unspecified Type of Bypass Graft(s) of Right Leg with Ulceration of Other Part of Lower Leg

description: Evidence of atherosclerosis of unspecified type of bypass graft(s) of right leg with ulceration of other part of lower leg.


name: Death Due to Multi-Organ Failure Not Associated with More Specific Term, CTCAE


name: Lugano Classification Stage II Childhood Hodgkin Lymphoma AJCC v8

description: Stage II: Involvement of two or more lymph node regions on the same side of the diaphragm. (from AJCC 8th Ed.)


Cutaneous Juvenile Xanthogranuloma

description: A benign histiocytic tumor that arises from the skin and occurs during childhood; it is distinct from Langerhans cell histiocytosis. It is characterized by the presence of lipid-laden, foamy histiocytes and Touton-type giant cells in the dermis. The lesions usually develop during infancy. They consist of cutaneous papules and nodules (most often in the head and neck).


name: Rheumatoid Myopathy with Rheumatoid Arthritis of Left Ankle and Foot

description: Evidence of rheumatoid myopathy with rheumatoid arthritis of left ankle and foot.


name: Other Psychoactive Substance Dependence with Sexual Dysfunction

description: Evidence of other psychoactive substance dependence with sexual dysfunction not specified elsewhere.


name: Rheumatoid Polyneuropathy with Rheumatoid Arthritis of Right Wrist

description: Evidence of rheumatoid polyneuropathy with rheumatoid arthritis of right wrist.


Retinoblastoma cT3 TNM Finding v7

description: Severe intraocular disease. (from AJCC 7th Ed.)


Cutaneous Melanoma cN3b TNM Finding v8

description: Cutaneous melanoma with four or more nodal metastases, at least one of which was clinically detected, or presence of any number of matted nodes. Presence of in-transit, satellite, and/or microsatellite metastases: No.  (from AJCC 8th Ed.)


name: Other Juvenile Arthritis, Unspecified Wrist

description: Evidence of other juvenile arthritis in an unspecified wrist not specified elsewhere.


name: Mantle Cell Lymphoma, Lymph Nodes of Axilla and Upper Limb

description: Evidence of mantle cell lymphoma in the lymph nodes of axilla and upper limb.


Grade 1 Edema Face, CTCAE

description: Localized facial edema


name: Pathologic Stage IVA Esophageal Adenocarcinoma AJCC v8

description: Stage IVA includes: (T4a, N2, M0, Any G); (T4b, N0-2, M0, Any G); (Any T, N3, M0, Any G). T4a: Tumor invades the pleura, pericardium, azygos vein, diaphragm, or peritoneum. T4b: Tumor invades other adjacent structures, such as the aorta, vertebral body, or airway. N0: No regional lymph node metastasis. N1: Tumor with metastasis in one or two regional lymph nodes. N2: Tumor with metastasis in three to six regional lymph nodes. N3: Tumor with metastasis in seven or more regional lymph nodes. M0: No distant metastasis. (AJCC 8th ed.)


Cervical Cancer cT1b TNM Finding v7

description: Cervical cancer with clinically visible lesion confined to the cervix. (from AJCC 7th Ed.)


Normal Point of Maximum Impulse

description: A clinical finding in which the point of maximum impulse is located in the midclavicular line, fifth intercostal space.


Epilepsy congenital

description: A seizure disorder that is present at the time of birth.


name: Stage IIIA Cervical Cancer AJCC v6 and v7

description: Stage IIIA includes: T3a, N0, M0.  T3a: Tumor involves lower third of vagina, no extension to pelvic wall.  N0: No regional lymph node metastasis.  M0: No distant metastasis. (AJCC 6th and 7th eds.)


Activating ALK Gene Mutation Negative

description: A genetic finding indicating that mutations in the ALK gene which encode constitutively active forms of the ALK tyrosine kinase receptor protein are not present in a sample.


name: Grade 1 Lower Gastrointestinal Hemorrhage NOS, CTCAE


name: Rheumatoid Heart Disease with Rheumatoid Arthritis of Unspecified Knee

description: Evidence of rheumatoid heart disease with rheumatoid arthritis of unspecified knee.


Hematosalpinx, CTCAE

description: A disorder characterized by the presence of blood in a fallopian tube.


name: Grade 2 Leukoencephalopathy Radiographic Findings, CTCAE


name: Grade 3 Rash Hand or Foot Skin Reaction, CTCAE


name: Recurrence of Primary in Seminal Vesicles

description: A recurrence of disease at the site of the primary lesion in the seminal vesicles.


Grade 2 Enterocolitis Infectious, CTCAE

description: Passage of >3 unformed stools per 24 hrs or duration of illness >48 hrs; moderate abdominal pain; oral intervention indicated (e.g., antibiotic, antifungal, or antiviral)


name: Vaginal Cancer Pathologic Regional Lymph Nodes TNM Finding v7

description: A pathologic finding about one or more characteristics of vaginal cancer, following the rules of the TNM AJCC v7 classification system as they pertain to staging of regional lymph nodes.


name: Injury to spleen with open wound into cavity

description: Trauma to the spleen associated with a break in the tissue that extends into the abdominal cavity.


name: Grade 3 Uterus Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


name: Grade 3 Cytomegalovirus Infection Reactivation, CTCAE

description: Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; IV intervention indicated


description: Evidence of opioid abuse with opioid-induced mood disorder.


name: Major Salivary Gland Cancer pN2a TNM Finding v6 and v7

description: Major salivary gland cancer with metastasis in a single ipsilateral lymph node, more than 3 cm but not more than 6 cm in greatest dimension. (from AJCC 6th and 7th Eds.)


Chemically Induced Cytotoxicity

description: The adverse effect of some iatrogenic therapies. It is an accepted side effect in radiation therapy where the desired effect is to kill rapidly growing tumor cells.  In the killing of tumor cells, other cells that are rapidly growing e.g hair, mucous membranes are also killed.


name: Grade 2 Liver Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


Appendix Tubulovillous Adenoma

description: An adenoma arising from the appendix.  It is characterized by the presence of tubular and villous epithelial structures and it is associated with dysplasia.


Favorable Hodgkin Lymphoma

description: A Hodgkin lymphoma with favorable prognosis.


Unspecified dermatitis due to sun

description: Inflammation of the skin resulting from exposure to the sun.


Gastric Hemorrhage, CTCAE

description: A disorder characterized by bleeding from the gastric wall.


name: Drug or Chemical Induced Diabetes Mellitus with Neurological Complication with Diabetic Autonomic Polyneuropathy

description: Evidence of drug or chemical induced diabetes mellitus with neurological complication with diabetic autonomic polyneuropathy.


name: Malignant Neoplasm of Upper Lobe, Left Bronchus or Lung

description: Evidence of a malignant neoplasm of the upper lobe in the left bronchus or lung.


Mild major depression, single episode

description: Evidence of major depressive disorder that is a single episode and is mild.


Hyperkalemia, CTCAE

description: A disorder characterized by laboratory test results that indicate an elevation in the concentration of potassium in the blood; associated with kidney failure or sometimes with the use of diuretic drugs.


name: Grade 5 Genitourinary Stoma Obstruction, CTCAE


CMV Molecular Test Result

description: The outcome of cytomegalovirus molecular testing.


name: Intraoperative Head and Neck Injury, CTCAE

description: A finding of damage to the head and neck during a surgical procedure.


Stage III Testicular Cancer AJCC v8

description: Stage III includes: Any pT/TX, Any N, M1, SX. TX: Testicular cancer in which the primary tumor cannot be assessed. M1: Testicular cancer with distant metastasis. SX: Marker studies not available or not performed. (AJCC 8th ed.)


name: Other Atherosclerosis of Other Type of Bypass Graft(s) of the Extremities, Other Extremity

description: Evidence of other atherosclerosis of other type of bypass graft(s) of the extremities, other extremity not specified elsewhere.


Benign Musculoskeletal Neoplasm

description: A mesenchymal neoplasm that arises from muscle or bone and is characterized by the absence of atypical or malignant cytological and architectural features, and absence of invasive features or metastatic potential.


name: Grade 2 Pelvis NOS Intra-Operative Injury, CTCAE


Grade 5 Febrile Neutropenia, CTCAE

description: Death


name: Ovarian, Fallopian Tube, and Primary Peritoneal Carcinoma pTX TNM Finding v8

description: Ovarian, fallopian tube, or primary peritoneal carcinoma in which the primary tumor cannot be assessed. (from AJCC 8th Ed.)


Gastric Cancer pT1b TNM Finding v7

description: Gastric cancer invading the submucosa. (from AJCC 7th Ed.)


name: Acute Myeloid Leukemia with t(5;17)(q35;q21); NPM1-RARA

description: Acute myeloid leukemia with the variant RARA t(5;17)(q35;q21) and the expression of NPM1-RARA fusion protein.


name: Cocaine Use, Unspecified with Cocaine-Induced Psychotic Disorder, Unspecified

description: Evidence of cocaine use, unspecified with cocaine-induced psychotic disorder.


name: Vaginal intraepithelial neoplasia grade 1

description: Vaginal intraepithelial neoplasia characterized by the presence of koilocytosis and disorganization and thickening of the basal layer.


Hyperpigmentation, CTCAE

description: An adverse reaction characterized by darkening of the skin.


name: Major Salivary Gland Cancer pT1 TNM Finding v6 and v7

description: Major salivary gland cancer with tumor 2 cm or less in greatest dimension without extraparenchymal extension. Extraparenchymal extension is clinical or macroscopic evidence of invasion of soft tissues. Microscopic evidence alone does not constitute extraparenchymal extension for classification purposes. (from AJCC 6th and 7th Eds.)


name: Other specified types of non-Hodgkin lymphoma, lymph nodes of inguinal region and lower limb

description: Evidence of other specified types of non-Hodgkin lymphoma in the lymph nodes of inguinal region and lower limb not specified elsewhere.


Grade 1 Virilization, CTCAE

description: Mild symptoms; intervention not indicated


Grade 4 Hypermagnesemia, CTCAE

description: >8.0 mg/dL; >3.30 mmol/L; life-threatening consequences


PSA Doubling Time Greater than 3 Months

description: An indication that it took more than three months for a subject's blood concentration of prostate specific antigen to double.


name: Localized Digestive System Neuroendocrine Tumor G1

description: Digestive system neuroendocrine tumor G1 that is restricted to the site of origin without evidence of metastasis.


name: Distal Bile Duct Cancer pTX TNM Finding v8

description: Distal bile duct cancer in which the primary tumor cannot be assessed. (from AJCC 8th Ed.)


name: Pulmonary and Upper Respiratory Hemorrhage, CTCAE


name: Grade 1 Vulva Intra-Operative Injury, CTCAE


name: Grade 5 Colon Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


secondary carcinoid tumor of bone

description: Evidence of secondary carcinoid tumors of bone.


Cutaneous Melanoma cN1b TNM Finding v8

description: Cutaneous melanoma with one clinically detected nodal metastasis. Presence of in-transit, satellite, and/or microsatellite metastases: No.  (from AJCC 8th Ed.)


name: Grade 2 Spermatic Cord Hemorrhage, CTCAE

description: Moderate symptoms; intervention indicated


Vitreous Seeding

description: The spread of tumor cells into the vitreous of the eye.


name: Grade 2 Bladder Intra-Operative Injury, CTCAE


name: Nodular Lymphocyte Predominant Hodgkin Lymphoma, Lymph Nodes of Multiple Sites

description: Evidence of nodular lymphocyte predominant Hodgkin lymphoma in the lymph nodes of multiple sites.


Uveal Melanoma pM1c TNM Finding v8

description: Uveal melanoma with largest diameter of the largest metastasis 8.1 cm or more. (from AJCC 8th Ed.)


name: Skin Squamous Cell Carcinoma or Other Skin Carcinomas Pathologic Distant Metastasis TNM Finding v7

description: A pathologic finding about one or more characteristics of skin squamous cell carcinoma or other skin carcinomas, following the rules of the TNM AJCC v7 classification system as they pertain to distant metastases. (from AJCC 7th Ed.)


name: Other Dermatomyositis with Other Organ Involvement

description: Evidence of other dermatomyositis with other organ involvement not specified elsewhere.


Grade 4 Depression, CTCAE

description: Life-threatening consequences, threats of harm to self or others; hospitalization indicated


Fine motor delay

description: Delayed acquisition of age appropriate motor milestones that produce small and precise movements.


name: Recurrent Malignant Endocervical Neoplasm

description: The reemergence of a malignant neoplasm of the endocervix after a period of remission.


Prostate Cancer cM0 TNM Finding v8

description: Prostate cancer without evidence of distant metastasis. (from AJCC 8th Ed.)


name: Vulvar Cancer Pathologic Distant Metastasis TNM Finding v8

description: A pathologic finding about one or more characteristics of vulvar cancer, following the rules of the TNM AJCC v8 classification system as they pertain to distant metastases.


Anal Cancer cM0 TNM Finding v8

description: Anal cancer without evidence of distant metastasis. (from AJCC 8th Ed.)


name: Grade 3 Soft Tissue Infection NOS with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


Urethral Cancer pNX TNM Finding v7

description: Urethral cancer in which the regional lymph nodes cannot be assessed. (from AJCC 7th Ed.)


Liver Cancer cM1 TNM Finding v7

description: Liver cancer with distant metastasis. (from AJCC 7th Ed.)


name: Stage IA Gestational Trophoblastic Tumor AJCC v7

description: Stage IA includes: T1, M0, Risk factors: low risk.  T1: Tumor confined to uterus.  M0: No distant metastasis.  (AJCC 7th ed.)


Other Drug-Induced Pancytopenia

description: Evidence of other drug-induced pancytopenia not specified elsewhere.


name: Grade 4 Biliary Tree Infection with Unknown Absolute Neutrophil Count, CTCAE


name: Adrenal Cortical Carcinoma pT2 TNM Finding v8

description: Tumor measuring more than 5 cm in greatest dimension, with no extra-adrenal invasion. (from AJCC 8th Ed.)


name: Sclerodermatous Graft Versus Host Disease

description: A rare form of chronic graft-versus-host disease characterized by cutaneous features and/or mucocutaneous features including sclerosis, atrophy, and contractures. It may manifest as localized or generalized disease.


Chronic Myelomonocytic Leukemia-1

description: A chronic myelomonocytic leukemia characterized by the presence of less than 10 percent blasts in the bone marrow and less than 5 percent blasts in the peripheral blood.


name: CA125 to CEA Ratio Greater than or Equal to 25

description: An indication that the ratio of CA125 antigen to carcinoembryonic antigen (CEA) found in a sample is greater than or equal to 25.


Complex Nodule Shape

description: A complex shape has no normally geometric shape and combines multiple more simple shapes. If no classically defined shape applies, the lesion is likely complex.


name: Post-Immunization Arthropathy, Unspecified Wrist

description: Evidence of post-immunization arthropathy in an unspecified wrist.


name: Localization-Related Idiopathic Epilepsy and Epileptic Syndromes with Seizures of Localized Onset, Intractable, without Status Epilepticus

description: Evidence of localization-related idiopathic epilepsy and epileptic syndromes with seizures of localized onset, without status epilepticus that does not respond optimally to treatment.


name: Stage 0 Gallbladder Cancer AJCC v6 and v7

description: Stage 0 includes: (Tis, N0, M0).  Tis: Carcinoma in situ.  N0: No regional lymph node metastasis.  M0: No distant metastasis. (AJCC 6th and 7th Eds.)


name: Hypertensive Heart and Chronic Kidney Disease with Heart Failure and with Stage 5 Chronic Kidney Disease, or End Stage Renal Disease

description: Evidence of hypertensive heart and chronic kidney disease with heart failure and with stage 5 chronic kidney disease, or end stage renal disease.


name: Overlapping malignant neoplasm of floor of mouth

description: Evidence of a malignant neoplasm of overlapping sites of the floor of mouth.


Disease Phase

description: The stage or period of an individual's disease.


Drug Use Complicating the Puerperium

description: Evidence of drug use complicating the puerperium.


description: Evidence of alcohol abuse with alcohol-induced sleep disorder.


name: Wound Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


Differentiated Granulocytic Sarcoma

description: A granulocytic sarcoma composed of promyelocytes and more mature neutrophils (WHO 2001).


name: Malignant mesothelioma of tunica vaginalis

description: A rare malignant mesothelioma that arises from the tunica vaginalis.


name: Carcinoma of the Conjunctiva Clinical Distant Metastasis TNM Finding v7

description: A clinical finding about one or more characteristics of carcinoma of the conjunctiva, following the rules of the TNM AJCC v7 classification system as they pertain to distant metastases.


name: Grade 2 Testes Stricture or Stenosis, CTCAE


ROS1 Driver Mutation Negative

description: A genetic finding indicating that disease-causing mutations in the ROS1 gene were not detected in a sample.


name: Grade 3 Dental-Tooth Infection with Unknown Absolute Neutrophil Count, CTCAE


Grade 3 Burn, CTCAE

description: Moderate to major debridement or reconstruction indicated


Celosomy

description: A developmental abnormality characterized by the complex protrusion of viscera outside the abdominal wall.


PSA Level Less than Thirty

description: A blood concentration of prostate specific antigen less than 30 ng/mL.


Phobia, School

description: An overwhelming, irrational, and persistent fear of attending school.


name: Hepatitis B Virus Core Antibody Negative

description: An indication that antibodies that recognize a hepatitis B virus core protein have not been detected in a sample.


name: Testosterone Less than or Equal to 100 ng/dL

description: A semiquantitative finding indicating that the concentration of testosterone in a sample is less than or equal to 100 ng/dL.


ERBB2 Gene Mutation Negative

description: A genetic finding indicating that ERBB2 gene mutations have not been detected in a sample.


Grade 2 Uterine Obstruction, CTCAE

description: Symptomatic; elective intervention indicated


Grade 5 Injury To Jugular Vein, CTCAE

description: Death


name: squamous cell carcinoma of urinary tract

description: A rare squamous cell carcinoma that arises from the urinary tract. Almost all cases have been reported in the bladder. Causes include urinary stasis, recurrent chronic inflammation, and smoking. In regions where schistosomiasis is endemic, it is the major etiologic factor of bladder squamous cell carcinoma.


name: Grade 1 International Normalized Ratio of Prothrombin Time, CTCAE


name: Major Salivary Gland Cancer Pathologic Regional Lymph Nodes TNM Finding v6

description: A pathologic finding about one or more characteristics of major salivary gland cancer, following the rules of the TNM AJCC v6 classification system as they pertain to staging of regional lymph nodes.


PSA Level Less than or Equal to Eleven

description: A blood concentration of prostate specific antigen less than or equal to 11 ng/mL.


name: Retinoblastoma Clinical Regional Lymph Nodes TNM Finding v7

description: A clinical finding about one or more characteristics of retinoblastoma, following the rules of the TNM AJCC v7 classification system as they pertain to staging of regional lymph nodes.


Grade 1 Cognitive Disturbance, CTCAE

description: Mild cognitive disability; not interfering with work/school/life performance; specialized educational services/devices not indicated


Grade 3 Tracheitis, CTCAE

description: IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated


Diffuse Mixed-Cell Lymphoma

description: An antiquated term referring to non-Hodgkin lymphomas with a mixed cellular composition. This term applies to both B- and T- cell non-Hodgkin lymphomas.


name: Malignant neoplasm of aortic body and other paraganglia

description: Evidence of a malignant neoplasm of the aortic body and other paraganglia.


Grade 1 GGT Increased, CTCAE

description: >ULN-2.5 x ULN if baseline was normal; 2.0-2.5 x baseline if baseline was abnormal


name: Grade 1 Muscle Weakness Left-Sided, CTCAE

description: Symptomatic; perceived by patient but not evident on physical exam


name: Grade 3 Catheter Related Infection, CTCAE


name: Grade 3 Blood Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


name: Grade 5 Stomach Mucositis or Stomatitis by Functional or Symptomatic Classification, CTCAE


name: Grade 4 Pancreatic Endocrine Glucose Intolerance, CTCAE


Agonizing Pain

description: A sensation of great anguish and suffering.


name: Recurrent Cervical Squamous Cell Carcinoma

description: The reemergence of cervical squamous cell carcinoma after a period of remission.


name: Intrahepatic Bile Duct Microcystic Adenoma

description: An adenoma that arises from the intrahepatic bile ducts and it is characterized by the presence of microcystic changes.


name: Grade 3 Cervical Spine Range of Motion, CTCAE


Follicular Lymphoma Grade II, Spleen

description: Evidence of follicular lymphoma grade II in the spleen.


Refractory WHO Grade 3 Glioma

description: A WHO grade 3 glioma that is resistant to treatment.


name: Other Atherosclerosis of Non-Biological Bypass Graft(s) of the Extremities, Unspecified Extremity

description: Evidence of other atherosclerosis of non-biological bypass graft(s) of the extremities, unspecified extremity not specified elsewhere.


10q23/PTEN Locus Deletion Negative

description: A genetic finding indicating that deletion of 10q23/PTEN has not been detected in a sample.


Non-Hematologic Malignancy

description: A malignant neoplasm that arises from a site other than the bone marrow and lymphoid tissue.


name: Nasal Cavity and Paranasal Sinuses Cancer TNM Finding v8

description: A finding about one or more characteristics of nasal cavity and paranasal sinuses cancer, following the rules of the TNM AJCC v8 classification system. This staging system applies to malignancies that arise in the epithelial lining of the nasal cavity and paranasal sinuses, with the exception of lymphoma and sarcoma. Mucosal melanoma of the nasal cavity and paranasal sinuses is staged according to the classification for mucosal melanoma of the head and neck. (from AJCC 8th Ed.)


name: Metastatic Micropapillary Urothelial Carcinoma

description: Micropapillary urothelial carcinoma that has spread to another anatomic site.


name: Colorectal Neuroendocrine Tumor pT1b TNM Finding v8

description: Colorectal neuroendocrine tumor measuring 1-2 cm in greatest dimension. (from AJCC 8th Ed.)


name: Ampulla of Vater Cancer Pathologic Distant Metastasis TNM Finding v7

description: A pathologic finding about one or more characteristics of ampulla of Vater cancer, following the rules of the TNM AJCC v7 classification system as they pertain to distant metastases.  There is no pathologic M0 for ampulla of Vater cancer. (from AJCC 7th Ed.)


name: Pathologic Stage II Cutaneous Melanoma AJCC v8

description: Stage II includes: IIA: (T2b, N0, M0); (T3a, N0, M0); IIB: (T3b, N0, M0); (T4a, N0, M0); IIC: (T4b, N0, M0). T2b: Tumor measuring more than 1.0 and equal to or less than 2.0 mm in thickness. Ulceration status: With ulceration. T3a: Tumor measuring more than 2.0 and equal to or less than 4.0 mm in thickness. Ulceration status: Without ulceration. T3b: Tumor measuring more than 2.0 and equal to or less than 4.0 mm in thickness. Ulceration status: With ulceration. T4a: Tumor measuring more than 4.0 mm in thickness. Ulceration status: Without ulceration. T4b: Tumor measuring more than 4.0 mm in thickness. Ulceration status: With ulceration.  N0: No regional lymph node metastasis detected. Presence of in-transit, satellite, and/or microsatellite metastases: No. M0: No evidence of distant metastasis. LDH level is not applicable. (AJCC 8th ed.)


Organ Failure

description: The failure of an essential system in the body.


name: Cerebral Infarction due to Thrombosis of Unspecified Carotid Artery

description: Evidence of cerebral infarction due to a thrombosis of unspecified carotid artery.


Stage IC Fallopian Tube Cancer AJCC v8

description: Stage IC includes: T1c, N0, M0. T1c: Fallopian tube cancer with tumor limited to fallopian tubes, with any of the following: surgical spill, capsule ruptured before surgery or tumor on fallopian tube surface, or malignant cells in ascites or peritoneal washings. N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 8th Ed.)


name: Epilepsy, Unspecified, Intractable, with Status Epilepticus

description: Evidence of unspecified epilepsy with status epilepticus that does not respond optimally to treatment.


Metastatic gastric adenocarcinoma

description: A gastric adenocarcinoma that has spread from its original site of growth to another anatomic site.


Cervical Cancer cNX TNM Finding v7

description: Cervical cancer in which regional lymph nodes cannot be assessed. (from AJCC 7th Ed.)


name: Endometrial Endometrioid Adenocarcinoma with Small Glands, Tubules or Cords


name: Displacement of heart valve prosthesis, sequela

description: Evidence of displacement of heart valve prosthesis, sequela.


Unresectable Vulvar Carcinoma

description: Vulvar carcinoma that is not amenable to surgical resection.


name: No Evidence of YAP1 and ZFTA Gene Rearrangements Present

description: A finding indicating that the rearrangement status of YAP1 and ZFTA genes in a tumor sample is unknown or negative.


name: Grade 3 Esophagus Mucositis or Stomatitis by Clinical Examination Classification, CTCAE


Stage I Gastric Cancer AJCC v6

description: Stage I includes: IA: (T1, N0, M0) and IB: (T1, N1, M0); (Ta/b, N0, M0).  T1: Tumor invades lamina propria or submucosa.  T2: Tumor invades the muscularis propria or the subserosa.  T2a: Tumor invades muscularis propria. T2b: Tumor invades subserosa.  N0: No regional lymph node metastasis.  N1: Metastasis in 1 to 6 regional lymph nodes.  N2: Metastasis in 7 to 15 regional lymph nodes.  M0: No distant metastasis. (AJCC 6th ed.)


COL1A2 Gene Promoter Hypermethylation

description: A genetic finding indicating that an excess of DNA methylation in the promoter region of the COL1A2 gene has been detected in a sample.


Dysesthesia, CTCAE

description: A disorder characterized by distortion of sensory perception, resulting in an abnormal and unpleasant sensation.


name: Soft Tissue Sarcoma of the Head and Neck TNM Finding v8

description: A finding about one or more characteristics of soft tissue sarcoma of the head and neck, following the rules of the TNM AJCC v8 classification system. This classification system applies to soft tissue sarcomas of the head and neck except angiosarcoma, rhabdomyosarcoma of the embryonal and alveolar subtype, Kaposi sarcoma, and dermatofibrosarcoma protuberans, which do not share the same behavior and natural history. This is a new classification system that needs data collection before defining a stage grouping for head and neck sarcomas. Sarcomas of the orbit are staged according to the orbital sarcoma classification system. (from AJCC 8th Ed.)


name: Other Malignant Neoplasm Skin of Left Ear and External Auricular Canal

description: Evidence of other malignant neoplasm skin of the left ear and external auricular canal not specified elsewhere.


Esophageal Mass

description: An abnormal growth located in the esophagus.


name: Cannabis Use, Unspecified with Psychotic Disorder with Delusions

description: Evidence of cannabis use, unspecified with psychotic disorder with delusions.


name: Grade 4 Spinal Cord Intra-Operative Injury, CTCAE


name: Paranasal Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


name: Chronic or unspecified gastric ulcer with haemorrhage

description: Evidence of chronic or unspecified gastric ulcer with hemorrhage.


name: Grade 5 Bronchus Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


Other Motor Neuron Disease

description: Evidence of other motor neuron disease not specified elsewhere.


name: Stage I Ampulla of Vater Neuroendocrine Tumor AJCC v8

description: Stage I includes: T1, N0, M0. T1: Tumor measuring 1 cm or less and is confined within the sphincter of Oddi. N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 8th ed.)


Neuronevus

description: An intradermal nevus characterized by the presence of nests of atrophic nevus cells which are hyalinized and resemble nerve bundles.


description: Evidence of inhalant abuse with intoxication delirium.


Superior Vena Cava Syndrome, CTCAE

description: A disorder characterized by obstruction of the blood flow in the superior vena cava. Signs and symptoms include swelling and cyanosis of the face, neck, and upper arms, cough, orthopnea and headache.


name: Breast Cancer Pathologic Primary Tumor TNM Finding v7

description: A pathologic finding about one or more characteristics of breast cancer, following the rules of the TNM AJCC v7 classification system as they pertain to staging of the primary tumor.  The TNM pathologic and clinical primary tumor classifications of breast cancer are the same, regardless of whether they are based on pathologic and/or clinical criteria.


Soft Tissue Sarcoma TNM Finding v7

description: A finding about one or more characteristics of soft tissue sarcoma, following the rules of the TNM AJCC v7 classification system.  Kaposi sarcoma, fibromatosis (desmoid tumor), and sarcoma arising from the dura mater, brain, parenchymatous organs, or hollow viscera are not included in this classification. (from AJCC 7th Ed.)


name: HER2/Neu Expression by Immunohistochemistry 2+

description: An immunohistochemical result of 2+ for HER2/Neu expression that is considered equivocal for expression.


Late effect of radiation

description: Late radiation injury (LRI) is the damage to the soft tissue and bone following radiation therapy that occurs weeks and years after the radiation exposure. Pathogenesis of LRI stems from ischemia, interruption of the blood supply and direct cell damage. LRIs include but not limited to the skin atrophy, ulceration and non-healing wounds; cystitis, proctosigmoiditis, resulting to fistulas, abscesses, fibrosis and scaring; laryngitis, osteoradionecrosis; central nervous system injury, optic neuropathy.


MGMT-Unmethylated Glioblastoma

description: A glioblastoma characterized by the absence of DNA methylation in the promoter region of the MGMT gene. It is associated with a poor outcome.


Shunt thrombosis

description: The presence of a thrombus within a vascular shunt.


name: Microbial IC95 Fold Change from Baseline

description: A fold change based on the concentration of a specific drug expected to produce 95 percent inhibition on the enzymatic activity of a microbial organism; it is a ratio calculated by the current IC95 Subject Result divided by the IC95 Subject Result from the baseline visit.


name: Grade 3 Thrombotic Thrombocytopenic Purpura, CTCAE

description: Laboratory findings with clinical consequences (e.g., renal insufficiency, petechiae)


Simple Breath Holding

description: A clinical condition in which there is a breath-holding spell without syncope. (ACC/AHA)


name: Benign Peritoneal and Retroperitoneal Neoplasm

description: A neoplasm that arises from the peritoneum and/or retroperitoneum and is characterized by the absence of atypical or malignant cytological and architectural features, and absence of invasive features or metastatic potential.


Grade 4 Ileus, CTCAE

description: Life-threatening consequences; urgent intervention indicated


name: Metastatic Large Cell Neuroendocrine Carcinoma

description: A large cell neuroendocrine carcinoma that has metastasized from its original site of growth to another anatomic site.


8/8 HLA Match

description: Complete HLA matching for HLA-A, -B, -C, and -DRB1 loci.


name: Localized Childhood Astrocytoma by Toronto Guidelines v2

description: Localized disease. (Childhood cancer staging for population registries according to the Toronto Childhood Cancer Stage Guidelines - Version 2. Cancer Council Queensland and Cancer Australia: Brisbane, Australia; 2021.)


Stage IIIA Bladder Cancer AJCC v8

description: Stage IIIA includes: (T3a, T3b, T4a, N0, M0); (T1-T4a, N1, M0). T1: Tumor invades lamina propria (subepithelial connective tissue). T2: Tumor invades muscularis propria. T3: Tumor invades perivesical soft tissue. T3a: Tumor invades perivesical soft tissue, microscopically. T3b: Tumor invades perivesical soft tissue, macroscopically (extravesical mass). T4a: Extravesical tumor invades directly into prostatic stroma, uterus, vagina. N0: No regional lymph node metastasis. N1: Single regional lymph node metastasis in the true pelvis (perivesical, obturator, internal and external iliac, or sacral lymph node). M0: No distant metastasis. (AJCC 8th ed.)


name: Grade 2 Lymphocyte Count Increased, CTCAE


name: Malignant Neoplasm of Lower-Outer Quadrant of Left Female Breast

description: Evidence of a malignant neoplasm of the lower-outer quadrant of left female breast.


name: Other juvenile arthritis, site unspecified

description: Evidence of other juvenile arthritis in an unspecified site not specified elsewhere.


Moderate Grade Fever

description: Body temperature ranging between 102.1 degrees Fahrenheit (39 degrees Celsius) and 103.9 degrees Fahrenheit (39.9 degrees Celsius).


name: Agoraphobia without history of panic disorder

description: An anxiety disorder characterized by agoraphobia in the absence of a history of panic attacks; the individual fears incapacitation or humiliation in open, public places or situations due to panic-like symptoms rather than a full-blown panic attack.


name: spondylopathy in diseases classified elsewhere in occipito-atlanto-axial region

description: Evidence of spondylopathy in diseases classified elsewhere in the occipito-atlanto-axial region.


Panic

description: A sudden and overwhelming sense of fear characterized by the inability to function as normal.


name: Stage II Childhood Retinoblastoma by Toronto Guidelines v2

description: Enucleation with microscopic residual disease. (Childhood cancer staging for population registries according to the Toronto Childhood Cancer Stage Guidelines - Version 2. Cancer Council Queensland and Cancer Australia: Brisbane, Australia; 2021.)


name: Atherosclerosis of Native Arteries of Left Leg with Ulceration of Unspecified Site

description: Evidence of atherosclerosis of native arteries of left leg with ulceration of unspecified site.


name: Ocular Adnexal Lymphoma pT1 TNM Finding v7

description: Lymphoma involving the conjunctiva alone without orbital involvement. (from AJCC 7th Ed.)


name: Monoplegia of Upper Limb following Non-Traumatic Intracerebral Hemorrhage Affecting Left Non-Dominant Side

description: Evidence of monoplegia of upper limb following non-traumatic intracerebral hemorrhage affecting left non-dominant side.


Bladder Cancer pT2a TNM Finding v6

description: Bladder cancer with invasion into the superficial muscle layer. (from AJCC 6th Ed.)


Alkaline Phosphatase Increased, CTCAE

description: A finding based on laboratory test results that indicate an increase in the level of alkaline phosphatase in a blood specimen.


Grade 5 Colonic Obstruction, CTCAE

description: Death


Responsive Disease

description: An indication that a patient's disease is responding to treatment.


name: Esophageal Glandular Intraepithelial Neoplasia

description: A lesion in which the architectural and cytologic abnormalities involve either the lower or both the lower and the upper half of the esophageal glandular epithelium.


Gingival Pain, CTCAE

description: A disorder characterized by a sensation of marked discomfort in the gingival region.


name: Type 2 Diabetes Mellitus with Proliferative Diabetic Retinopathy with Macular Edema, Bilateral

description: Evidence of type 2 diabetes mellitus with proliferative diabetic retinopathy with macular edema that is bilateral.


name: Grade 3 CNS Necrosis and Cystic Progression, CTCAE


HRAS Gene Mutation Negative

description: A genetic finding indicating that HRAS gene mutations have not been detected in a sample.


Cervical Yolk Sac Tumor

description: A yolk sac tumor that arises from the cervix. Patients present with abnormal vaginal bleeding and a polypoid, friable mass, protruding into the vagina.


Grade 1 Guillain-Barre Syndrome, CTCAE

description: Mild symptoms


name: Cerebral Infarction due to Unspecified Occlusion or Stenosis of Bilateral Middle Cerebral Artery

description: Evidence of cerebral infarction due to an unspecified occlusion or stenosis of the bilateral middle cerebral artery.


name: Merkel Cell Carcinoma cM1b TNM Finding v8

description: Merkel cell carcinoma with metastasis to lung. (from AJCC 8th Ed.)


Enterovesical Fistula

description: An abnormal communication between the urinary bladder and the intestine.


name: Grade 2 Supraventricular Arrhythmia NOS, CTCAE


name: Overlapping malignant neoplasm of palate

description: Evidence of a malignant neoplasm of overlapping sites of the palate.


Verruca Palmaris

description: A wart on the palmar surface of the hand. It is caused by human papillomavirus.


name: Spondylopathy in Diseases Classified Elsewhere, Multiple Sites in Spine

description: Evidence of spondylopathy in diseases classified elsewhere in multiple sites in spine.


name: Type 1 Diabetes Mellitus with Other Diabetic Ophthalmic Complication

description: Evidence of type 1 diabetes mellitus with other diabetic ophthalmic complication.


Anemia, CTCAE

description: A disorder characterized by a reduction in the amount of hemoglobin in 100 ml of blood. Signs and symptoms of anemia may include pallor of the skin and mucous membranes, shortness of breath, palpitations of the heart, soft systolic murmurs, lethargy, and fatigability.


name: Atherosclerosis of Autologous Vein Bypass Graft(s) of the Right Leg with Ulceration of Thigh

description: Evidence of atherosclerosis of autologous vein bypass graft(s) of the right leg with ulceration of thigh.


name: Pathologic Stage II Retinoblastoma AJCC v8

description: Stage II includes: pT4, pN0, cM0, Any H. pT4: Evidence of extraocular tumor: tumor at the transected end of the optic nerve, tumor in the meningeal spaces around the optic nerve, full-thickness invasion of the sclera with invasion of the episclera, adjacent adipose tissue, extraocular muscle, bone, conjunctiva, or eyelids. pN0: No lymph node involvement. cM0: No signs or symptoms of intracranial or distant metastasis. HX: Unknown or insufficient evidence of a constitutional RB1 gene mutation. H0: Normal RB1 alleles in blood tested with demonstrated high-sensitivity assays. H1: Bilateral retinoblastoma, retinoblastoma with an intracranial primitive neuroectodermal tumor (i.e., trilateral retinoblastoma), patient with family history of retinoblastoma, or molecular definition of a constitutional RB1 gene mutation. (AJCC 8th ed.)


Testicular Cancer cM0 TNM Finding v7

description: Testicular cancer without evidence of distant metastasis. (from AJCC 7th Ed.)


name: Major Salivary Gland Cancer pNX TNM Finding v8

description: Major salivary gland cancer in which the regional lymph nodes cannot be assessed. (from AJCC 8th Ed.)


Gallbladder Cancer TNM Finding v7

description: A finding about one or more characteristics of gallbladder cancer, following the rules of the TNM AJCC v7 classification system.  Carcinoid tumors and sarcomas are not included.  The cystic duct is now included in this classification scheme. (from AJCC 7th Ed.)


Leukocytosis, CTCAE

description: A disorder characterized by laboratory test results that indicate an increased number of white blood cells in the blood.


PSA Nadir Less than 0.5 ng/mL

description: A finding indicating that the lowest blood concentration of prostate specific antigen for a subject was less than 0.5 ng/mL.


Grade 2 Bladder Anastomotic Leak, CTCAE

description: Symptomatic; medical intervention indicated


name: Grade 4 Pelvis Infection NOS Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


Grade 2 Accessory Nerve Disorder, CTCAE

description: Moderate symptoms; limiting instrumental ADL


PSA Level Greater than Four

description: A blood concentration of prostate specific antigen greater than 4 ng/mL.


name: Ocular Adnexal Lymphoma cM1b TNM Finding v8

description: Ocular adnexal lymphoma with lymphomatous involvement of the bone marrow. (from AJCC 8th Ed.)


Recurrent Urethral Cancer

description: The reemergence of urethral carcinoma after a period of remission