name: Placental Site Nodule and Plaque Occurring in the Fallopian Tube

description: A rare non-neoplastic trophoblastic disorder characterized by the presence of remnants of intermediate trophoblasts in the fallopian tube from a previous pregnancy.


name: Grade 3 Pelvis Infection NOS with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE

category: biolink:PhenotypicFeature biolink:DiseaseOrPhenotypicFeature biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing


Locally Advanced Pancreatic Carcinoma

category: biolink:Disease biolink:DiseaseOrPhenotypicFeature biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing

description: A pancreatic carcinoma that has spread from its original site of growth to nearby tissues or lymph nodes.


Childhood Acute Erythroid Leukemia

description: An acute erythroid leukemia occurring in children.


Malaise, CTCAE

description: A disorder characterized by a feeling of general discomfort or uneasiness, an out-of-sorts feeling.


name: Colorectal Cancer pTis Intraepithelial TNM Finding

description: Colorectal cancer in situ in which cancer cells are confined within the glandular basement membrane (intraepithelial). (from CAP Colorectal Cancer Protocol-January 2005 Revision)


name: Grade 2 Hypoglossal Nerve Disorder, CTCAE

description: Moderate symptoms; limiting instrumental ADL


name: Verrucous carcinoma of the oral cavity stage I


name: Other dissociative [conversion] disorders

description: Evidence of other dissociative and conversion disorders not specified elsewhere.


name: Genetic Syndrome Associated with Congenital Heart Defect

description: Genetic anomalies and collections of malformations that are known to cluster together that can be associated with congenital heart defects. (ACC/AHA)


Tracheal Stenosis, CTCAE

description: A disorder characterized by a narrowing of the trachea.


Grade 1 Lip Pain, CTCAE

description: Mild pain


Laryngeal Cancer pM1 TNM Finding v8

description: Laryngeal cancer with distant metastasis. (from AJCC 8th Ed.)


name: Refractory Endometrial Serous Adenocarcinoma

description: Endometrial serous adenocarcinoma that is resistant to treatment.


name: Mucosal Melanoma of the Head and Neck Clinical TNM Finding v7

description: A clinical finding about one or more characteristics of mucosal melanoma of the head and neck, following the rules of the TNM AJCC v7 classification system.


Grade 2 Dyspepsia, CTCAE

description: Moderate symptoms; medical intervention indicated


name: Lacrimal Drainage System Adenoid Cystic Carcinoma

description: A carcinoma that arises from the lacrimal sac. It is characterized by the presence of malignant epithelial cells that form cribriform, tubular, and solid patterns.


Skin Hyperpigmentation, CTCAE

description: A disorder characterized by darkening of the skin due to excessive melanin deposition.


Duodenal Hemorrhage, CTCAE

description: A disorder characterized by bleeding from the duodenum.


name: Perihilar Bile Duct Cancer Clinical Distant Metastasis TNM Finding v8

description: A clinical finding about one or more characteristics of perihilar bile duct cancer, following the rules of the TNM AJCC v8 classification system as they pertain to distant metastases.


name: Recurrent Endometrial Dedifferentiated Carcinoma

description: The reemergence of endometrial dedifferentiated carcinoma after a period of remission.


Bladder Cancer pT4a TNM Finding v7

description: Bladder cancer with tumor invading prostatic stroma, uterus, vagina.  (from AJCC 7th Ed.)


name: Anaplastic Large Cell Lymphoma, ALK-Negative, Lymph Nodes of Multiple Sites

description: Evidence of anaplastic large cell lymphoma that is ALK-Negative in the lymph nodes of multiple sites.


name: Perihilar Bile Duct Cancer pT2b TNM Finding v8

description: Perihilar bile duct cancer with tumor invading adjacent hepatic parenchyma. (from AJCC 8th Ed.)


name: Pregnancy, Puerperium and Perinatal Conditions, CTCAE


Adult Benign Brain Neoplasm

description: A benign neoplasm of the brain occurring in adults.


name: Metastatic Prostate Adenocarcinoma with Neuroendocrine Differentiation

description: Prostate adenocarcinoma with neuroendocrine differentiation that has spread from its original site of growth to another anatomic site.


name: Dravet syndrome, intractable, without status epilepticus

description: Evidence of Dravet syndrome, without status epilepticus that does not respond optimally to treatment.


description: An improvement in erythrocyte count as a response to treatment.


PSA Level Greater than or Equal to 0.8

description: A blood concentration of prostate specific antigen greater than or equal to 0.8 ng/mL.


Grade 3 Myocarditis, CTCAE

description: Severe with symptoms at rest or with minimal activity or exertion; intervention indicated; new onset of symptoms


name: Grade 2 Transient Ischemic Attacks, CTCAE

description: Moderate neurologic deficit with or without imaging confirmation


Grade 2 Skin Hyperpigmentation, CTCAE

description: Hyperpigmentation covering >10% BSA; associated psychosocial impact


name: Clear Cell Tumor with Melanocytic Differentiation and ACTIN-MITF Translocation

description: A MITF pathway-activated melanocytic tumor characterized by a cytogenetic translocation between ACTIN and MITF genes that results in ACTIN-MITF gene fusion. It presents as a single non-pigmented cutaneous nodule in the distal extremities or trunk. It is composed of large cells with clear cytoplasm that exhibit melanocytic differentiation and proliferate in the dermis without an intraepidermal component. Extension in the subcutaneous tissue is frequently seen. Atypical nuclear features may be present. It has an indolent clinical course.


name: Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma, Unspecified, Intrathoracic Lymph Nodes

description: Evidence of an unspecified mature T-cell and NK-cell non-Hodgkin lymphoma in the intrathoracic lymph nodes.


Perforation

description: A hole or opening made through a membrane or other tissue or material.


name: Grade 1 Artery NOS Intra-Operative Injury, CTCAE


name: Carcinoma of the Conjunctiva pNX TNM Finding v7

description: Carcinoma of the conjunctiva in which the regional lymph nodes cannot be assessed.  (from AJCC 7th Ed.)


name: Cranial Nerve I Intra-Operative Injury, CTCAE


name: Glottic Cancer pN2b TNM Finding v6 and v7

description: Glottic cancer with metastasis in two or more ipsilateral nodes, none more than 6 cm in greatest dimension. (from AJCC 6th and 7th Eds.)


name: Metastatic Platinum-Resistant Malignant Germ Cell Tumor

description: A platinum-resistant malignant germ cell tumor that has spread from its original site of growth to another anatomic site.


Grade 4 Neck Edema, CTCAE

description: Vascular or respiratory impairment requiring urgent intervention


name: Juvenile Myoclonic Epilepsy, Intractable, with Status Epilepticus

description: Evidence of juvenile myoclonic epilepsy, with status epilepticus that does not respond optimally to treatment.


name: Mediastinal Germ Cell Tumor Distant Metastasis TNM Finding

description: A TNM finding about one or more characteristics of a mediastinal germ cell tumor as they pertain to distant metastases. (WHO Classification of Tumors of the Lung, Pleura, Thymus and Heart, 2015)


name: Lip and Oral Cavity Cancer cN2a TNM Finding v8

description: Lip and oral cavity cancer with metastasis in a single ipsilateral lymph node larger than 3 cm but not larger than 6 cm in greatest dimension and ENE(-).  (from AJCC 8th Ed.)


name: Grade 2 Cervix Infection with Unknown Absolute Neutrophil Count, CTCAE


Grade 1 Premature Delivery, CTCAE

description: Delivery of a liveborn infant at >34 to 37 weeks gestation


Grade 3 Rectal Ulcer, CTCAE

description: Severely altered GI function; TPN indicated; elective invasive intervention indicated


Testicular Cancer cM1a TNM Finding v8

description: Testicular cancer with non-retroperitoneal nodal or pulmonary metastases. (from AJCC 8th Ed.)


Peripheral Motor Neuropathy, CTCAE

description: A disorder characterized by damage or dysfunction of the peripheral motor nerves.


name: Breast Cancer pTis (DCIS) TNM Finding v6 and v7

description: Breast cancer with a finding of ductal carcinoma in situ. (from AJCC 6th and 7th Ed.)


Grade 5 Duodenal Fistula, CTCAE

description: Death


name: Adnexal Adenocarcinoma, Not Otherwise Specified

description: An adnexal carcinoma with ductal/glandular differentiation lacking specific histological features that would allow further classification. (WHO 2018)


description: A hematologic malignancy that arises in a patient with a history of organ transplantation.


name: Grade 3 Cranial Nerve Infection with Unknown Absolute Neutrophil Count, CTCAE


Grade 2 Ileal Perforation, CTCAE

description: Invasive intervention not indicated


name: Stomach Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


name: Ocular Adnexal Lymphoma Pathologic Regional Lymph Nodes TNM Finding v8

description: A pathologic finding about one or more characteristics of ocular adnexal lymphoma, following the rules of the TNM AJCC v8 classification system as they pertain to staging of regional lymph nodes.


name: Grade 3 CD4 Lymphocytes Decreased, CTCAE

description: <200-50/mm3; <0.2 x 0.05-10e9/L


name: Grade 4 Neuroendocrine ACTH Deficiency, CTCAE


Normal Expression

description: An indication that the expression level for a biological factor of interest is found within the normal range of values.


Childhood Benign Skin Neoplasm

description: A childhood neoplasm that arises from the skin and is characterized by the absence of atypical or malignant cytological and architectural features, and absence of invasive features or metastatic potential.


Grade 5 Vaginal Fistula, CTCAE

description: Death


Recurrent Endometrial Cancer

description: The reemergence of endometrial carcinoma after a period of remission.


name: Complex endometrial hyperplasia without atypia

description: A hyperplasia characterized by excessive proliferation of endometrial cells, resulting in the formation of complex epithelial structures. Epithelial atypia is absent.


Thyroid Cancer pT1b TNM Finding v7

description: Thyroid cancer with a tumor size of more than 1 cm but not more than 2 cm in greatest dimension, limited to the thyroid gland. (from AJCC 7th Ed.)


Chest Wall Disorder

description: A non-neoplastic or neoplastic disorder that affects the structures of the chest wall.  Representative examples include infection, chest wall lipoma, and chest wall lymphoma.


name: Grade 3 CNS Cerebrovascular Ischemia, CTCAE


Grade 3 Encephalopathy, CTCAE

description: Severe symptoms; limiting self care ADL


Metastatic adenoid cystic carcinoma

description: An adenoid cystic carcinoma that has spread from the original site of growth to other anatomic sites.


name: Grade 1 Reduction in Growth Velocity, CTCAE


Epstein-Barr virus infection recurrent

description: An Epstein-Barr virus infection that has recurred after a period of remission.


Cervical myelocele

description: Herniation of spinal cord tissue and meninges through a defect in the cervical region of the vertebral column. The protrusion of the tissue is flush with the level of the skin surface.


name: Metastatic Malignant Neoplasm in the Lacrimal System

description: A malignant neoplasm that has spread from its original site of growth to the lacrimal gland or lacrimal drainage system.


name: Somnolence and Depressed Level of Consciousness, CTCAE


Nutritional Hypophosphatemic Rickets

description: Hypophosphatemic rickets due to insufficient dietary phosphate intake or absorption.


Global Relapse in Skin

description: Any disease recurrence in those with complete response.


Hyperlipasaemia

description: A laboratory test result which indicates increased levels of lipase in a biologic specimen.


name: Grade 2 Neuroendocrine Growth Hormone Secretion Abnormality, CTCAE


Post-Dysenteric Arthropathy, Right Hand

description: Evidence of post-dysenteric arthropathy in the right hand.


Grade 1 Neonatal Constipation, AE

description: An adverse event in a newborn characterized by reduced number of stools or hard stools; no apparent discomfort.


name: Grade 5 Prolonged Intubation After Pulmonary Resection, CTCAE


Adult Intracranial Germ Cell Tumor

description: A germ cell tumor that arises within the cranium and occurs during adulthood.


post-traumatic seizures

description: Evidence of post traumatic seizures.


Rheumatoid Bursitis, Left Knee

description: Evidence of rheumatoid bursitis in the left knee.


name: Male Reproductive System Cancer TNM Finding v8

description: A finding about one or more characteristics of male reproductive system cancer, following the rules of the TNM AJCC v8 classification system. This classification system applies to penile cancer, prostate cancer, and testicular cancer.


name: Stage I Childhood Retinoblastoma by Toronto Guidelines v2

description: Enucleation with negative margins. (Childhood cancer staging for population registries according to the Toronto Childhood Cancer Stage Guidelines - Version 2. Cancer Council Queensland and Cancer Australia: Brisbane, Australia; 2021.)


Phlebitis of portal vein

description: Inflammation of the portal vein.


name: Grade 3 Bone Growth Limb Length Discrepancy, CTCAE


Basal-Like Prostate Carcinoma

description: Prostate carcinoma in which the CD49f signature is increased, the luminal markers and androgen receptor expression and signaling (androgen activity pathway) are not increased, and the proliferation score is higher than the luminal A prostate carcinoma.


Anal Fistula, CTCAE

description: A disorder characterized by an abnormal communication between the opening in the anal canal to the perianal skin.


name: Type 1 Diabetes Mellitus with Moderate Nonproliferative Diabetic Retinopathy without Macular Edema, Left Eye

description: Evidence of type 1 diabetes mellitus with moderate nonproliferative diabetic retinopathy without macular edema in the left eye.


Stage II Gallbladder Cancer AJCC v7

description: Stage II includes: T2, N0, M0.  T2: Tumor invades perimuscular connective tissue; no extension beyond serosa or into liver.  N0: No regional lymph node metastasis.  M0: No distant metastasis. (from AJCC 7th Ed.)


name: Grade 2 Laryngopharyngeal Dysesthesia, CTCAE

description: Moderate symptoms; mild anxiety, but no dyspnea; short duration of observation and/or anxiolytic indicated; limiting instrumental ADL


Grade 3 Urinary Fistula, CTCAE

description: Invasive intervention indicated


Gestational diabetes mellitus class A2

description: Carbohydrate intolerance first diagnosed during pregnancy. Diagnosis from abnormal oral glucose tolerance test (OGTT) and abnormal fasting or post-prandial glucose levels. Euglycemia achieved with medication.


name: Mediastinal Germ Cell Tumor T4 TNM Finding

description: Mediastinal germ cell tumor with pleural or pericardial dissemination. (WHO Classification of Tumors of the Lung, Pleura, Thymus and Heart, 2015)


name: Stage II Intermediate Grade Adult Non-Hodgkin's Lymphoma


name: Diffuse Large B-Cell Lymphoma, Lymph Nodes of Head, Face, and Neck

description: Evidence of diffuse large B-cell lymphoma, lymph nodes of head, face, and neck.


name: Stage IIIA Uterine Corpus Cancer AJCC v8

description: Stage IIIA includes: T3a, N0, M0. T3a: Uterine corpus carcinoma or carcinosarcoma with tumor involving the serosa and/or adnexa (direct extension or metastasis). N0: No regional lymph node metastasis. M0: No distant metastasis. (from AJCC 8th Ed.)


PSA Level Less than 0.5

description: An indication that a blood concentration of prostate specific antigen below 0.5 ng/mL was detected in a sample.


name: ALK-negative anaplastic large cell lymphoma of intrathoracic lymph nodes

description: Evidence of anaplastic large cell lymphoma that is ALK-Negative in the intrathoracic lymph nodes.


Rheumatoid Bursitis, Right Hip

description: Evidence of rheumatoid bursitis in the right hip.


name: Grade 2 Catheter Related Infection, CTCAE

description: Localized; local intervention indicated; oral intervention indicated (e.g., antibiotic, antifungal, or antiviral)


Tumor Lysis Syndrome, CTCAE 5.0

description: A disorder characterized by metabolic abnormalities that result from a spontaneous or therapy-related cytolysis of tumor cells.


Grade 5 Feeding Intolerance, AE

description: A feeding intolerance adverse event in a newborn which results in death.


Breast Cancer pN2 TNM Finding v8

description: Breast cancer with metastases in 4-9 axillary lymph nodes; or positive ipsilateral internal mammary lymph nodes by imaging in the absence of axillary lymph node metastases. (from AJCC 8th Ed.)


name: Head and Neck Cancer Pathologic Regional Lymph Nodes TNM Finding v8

description: A pathologic finding about one or more characteristics of head and neck cancer, following the rules of the TNM AJCC v8 classification system as they pertain to staging of regional lymph nodes.


name: Other Malignant Neoplasm Skin of Unspecified Lower Limb, Including Hip

description: Evidence of other malignant neoplasm skin of unspecified lower limb including the hip not specified elsewhere.


name: Grade 1 Upper Extremity Artery Intra-Operative Injury, CTCAE


name: Pre-Existing Essential Hypertension Complicating Pregnancy, Third Trimester

description: Evidence of pre-existing essential hypertension complicating pregnancy in the third trimester.


name: Papillary, Follicular, Hurthle Cell, Poorly Differentiated, and Anaplastic Thyroid Carcinoma Clinical TNM Finding v8

description: A clinical finding about one or more characteristics of papillary, follicular, Hurthle cell, poorly differentiated, and anaplastic thyroid carcinoma, following the rules of the TNM AJCC v8 classification system.


name: Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma, Unspecified, Lymph Nodes of Head, Face, and Neck

description: Evidence of an unspecified mature T-cell and NK-cell non-Hodgkin lymphoma in the lymph nodes of head, face, and neck.


Grade 4 Capillary Leak Syndrome, CTCAE

description: Life-threatening consequences; urgent intervention indicated


Unresectable Digestive System Carcinoma

description: Digestive system carcinoma that is not amenable to surgical resection.


Vulvar Cancer pTX TNM Finding v8

description: Vulvar cancer in which the primary tumor cannot be assessed. (from AJCC 8th Ed.)


name: Other Paralytic Syndrome following Non-Traumatic Intracerebral Hemorrhage, Bilateral

description: Evidence of other paralytic syndrome following non-traumatic intracerebral hemorrhage that is bilateral not specified elsewhere.


Recurrent basal cell carcinoma

description: The reemergence of basal cell carcinoma after a period of remission.


Unacceptable Toxicity

description: Therapy-related toxicity leading to multiple treatment dose reductions or delays, early treatment stoppage, unplanned hospital admission, or death.


name: Maxillary Sinus Cancer Pathologic TNM Finding v7

description: A pathologic finding about one or more characteristics of maxillary sinus cancer, following the rules of the TNM AJCC v7 classification system.  The pathologic staging requires the use of all information obtained in clinical staging and in histologic study of the surgically resected specimens.  The surgeon's evaluation of gross unresected residual tumor must also be included.  (from AJCC 7th Ed.)


Grade 1 Pericarditis, CTCAE

description: Asymptomatic, ECG or physical findings (e.g., rub) consistent with pericarditis


Melanoma of the Uvea pN0 TNM Finding v7

description: Melanoma of the uvea with no regional lymph node metastasis.  (from AJCC 7th Ed.)


Refractory Childhood Malignant Neoplasm

description: A childhood malignant neoplasm that does not respond to treatment.


Grade 1 Esophagitis, CTCAE

description: Asymptomatic; clinical or diagnostic observations only; intervention not indicated


name: Soft Tissue Sarcoma of the Trunk and Extremities pT0 TNM Finding v8

description: Soft tissue sarcoma of the trunk and extremities with no evidence of primary tumor. (from AJCC 8th Ed.)


name: Grade 2 Spinal Cord Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


description: Evidence of hallucinogen dependence with intoxication.


name: Cutaneous Melanoma by AJCC v8 Pathologic Stage

description: A term that refers to the pathologic staging of cutaneous melanoma, following the rules of the TNM AJCC v8 classification system.


name: Unspecified Pre-Existing Hypertension Complicating Pregnancy, Third Trimester

description: Evidence of unspecified pre-existing hypertension complicating pregnancy in the third trimester.


Grade 4 Hepatic Failure, CTCAE

description: Life-threatening consequences; moderate to severe encephalopathy; coma


name: Renal Pelvis and Ureter Cancer pTis TNM Finding v8

description: Renal pelvis and ureter cancer with a finding of carcinoma in situ. (from AJCC 8th Ed.)


ALK Gene Mutation Negative

description: A genetic finding indicating that ALK gene mutations have not been detected in a sample.


name: Gallbladder Cancer Pathologic TNM Finding v6

description: A pathologic finding about one or more characteristics of gallbladder cancer, following the rules of the TNM AJCC v6 classification system.


Current EBV Infection

description: Epstein-Barr virus infection is evident at the time of testing.


name: Distal Bile Duct Cancer pT2 TNM Finding v8

description: Distal bile duct cancer with tumor invading the bile duct wall with a depth of 5-12 mm. (from AJCC 8th Ed.)


Spine Cancer pTX TNM Finding v8

description: Spine cancer in which the primary tumor cannot be assessed. (from AJCC 8th Ed.)


name: Childhood Ependymoma by Toronto Guidelines v2 Stage, Tier 1

description: A term that refers to the staging of childhood ependymoma according to the tier 1 Toronto childhood cancer staging guidelines v2.


Vasculitic ulcer

description: A circumscribed inflammatory lesion associated with underlying ischemic disease.


Grade 4 Gum Infection, CTCAE

description: Life-threatening consequences; urgent intervention indicated


name: Cerebral Infarction due to Thrombosis Unspecified Precerebral Artery

description: Evidence of cerebral infarction due to a thrombosis of an unspecified precerebral artery.


Pulmonary Embolism Related to COVID-19

description: Pulmonary embolism in a patient with probable or confirmed acute COVID-19.


name: Grade 1 Superior Vena Cava Syndrome, CTCAE

description: Asymptomatic; incidental finding of SVC thrombosis


Human Anti-Mouse Antibodies Negative

description: Indicates that human anti-mouse antibodies have not been detected in a sample.


name: Gastric Neuroendocrine Tumor pT3 TNM Finding v8

description: Gastric neuroendocrine tumor invading through the muscularis propria into subserosal tissue without penetration of overlying serosa. (from AJCC 8th Ed.)


name: Other Stimulant Abuse with Intoxication with Perceptual Disturbance

description: Evidence of other stimulant abuse with intoxication with perceptual disturbance not specified elsewhere.


Vulvar Cancer TNM Finding v8

description: A finding about one or more characteristics of vulvar cancer, following the rules of the TNM AJCC v8 classification system. This classification system applies to all carcinomas of the vulva. Melanoma of the vulva is staged according to the classification for melanoma of the skin.   (from AJCC 8th Ed.)


name: Parathyroid Carcinoma Pathologic Regional Lymph Nodes TNM Finding v8

description: A pathologic finding about one or more characteristics of parathyroid carcinoma, following the rules of the TNM AJCC v8 classification system as they pertain to staging of regional lymph nodes.


Voice Alteration, CTCAE

description: A disorder characterized by a change in the sound and/or speed of the voice.


name: Grade 4 Upper Airway Infection NOS with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


Grade 2 Vertigo, CTCAE

description: Moderate symptoms; limiting instrumental ADL


Device embolization

description: Movement of a medical device to an unintended location within the body with resulting obstruction of an organ or vessel.


name: Gastric Neuroendocrine Tumor Pathologic Distant Metastasis TNM Finding v7

description: A pathologic finding about one or more characteristics of gastric neuroendocrine tumor, following the rules of the TNM AJCC v7 classification system as they pertain to distant metastases.  There is no pathologic M0 for gastric neuroendocrine tumor. (from AJCC 7th Ed.)


name: Grade 5 Bladder Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


name: Transient Retinal Artery Occlusion, Left Eye

description: Evidence of transient retinal artery occlusion in the left eye.


name: Appendiceal Carcinoma Clinical TNM Finding v8

description: A clinical finding about one or more characteristics of appendiceal carcinoma, following the rules of the TNM AJCC v8 classification system.


Third degree uterine prolapse

description: The uterus has descended below the level of the hymen and protrudes through the opening of the vagina.


Pneumothorax, CTCAE

description: A disorder characterized by abnormal presence of air in the pleural cavity resulting in the collapse of the lung.


Grade 4 Biliary Anastomotic Leak, CTCAE

description: Life-threatening consequences; urgent operative intervention indicated


name: atherosclerosis of other type of bypass graft of left leg with ulceration of thigh

description: Evidence of atherosclerosis of other type of bypass graft(s) of the left leg with ulceration of thigh.


Wood-Burning Factory Smoke Exposure

description: Environmental or occupational exposure to airborne gases and particulates produced when wood is burned in a factory setting.


Non-Neoplastic Chest Wall Disorder

description: A non-neoplastic disorder that affects the structures of the chest wall.


name: Bilateral occlusion of branch retinal arteries

description: Evidence of retinal artery branch occlusion that is bilateral.


name: Cutaneous Squamous Cell Carcinoma of the Head and Neck pT4 TNM Finding v8

description: Cutaneous squamous cell carcinoma of the head and neck with gross cortical bone/marrow, skull base invasion and/or skull base foramen invasion.  (from AJCC 8th Ed.)


Grade 1 Pulmonary Fistula, CTCAE

description: Asymptomatic


name: Grade 1 Fallopian Tube Hemorrhage, CTCAE


name: Stage III Pancreatic Cancer AJCC v6 and v7

description: Stage III includes: T4, Any N, M0. T4: Tumor involves the celiac axis or the superior mesenteric artery.  M0: No distant metastasis.  (AJCC 6th and 7th Eds.)


Grade 2 Esophagitis, CTCAE

description: Symptomatic; altered eating/swallowing; oral supplements indicated


name: Presence of Other Heart-Valve Replacement

description: Evidence of presence of other heart-valve replacement.


name: Hypopharyngeal Cancer pN1 TNM Finding v8

description: Hypopharyngeal cancer with metastasis in a single ipsilateral lymph node, 3 cm or smaller in greatest dimension and ENE (-). (from AJCC 8th Ed.)


Subglottic Cancer pT1 TNM Finding v8

description: Subglottic cancer in which the tumor is limited to the subglottis. (from AJCC 8th Ed.)


Adverse event

description: Any unfavorable or unintended disease, sign, or symptom (including an abnormal laboratory finding) that is temporally associated with the use of a medical treatment or procedure, and that may or may not be considered related to the medical treatment or procedure. Such events can be related to the intervention, dose, route of administration, patient, or caused by an interaction with another drug(s) or procedure(s).


name: Recurrent Acute Myeloid Leukemia with Multilineage Dysplasia

description: The reemergence of acute myeloid leukemia with multilineage dysplasia after a period of remission.


Grade 3 Breast Atrophy, CTCAE

description: Asymmetry >1/3 of breast volume; severe atrophy


Philadelphia Chromosome Negative

description: Indicates that the Philadelphia chromosome abnormality, t(9;22)(q34;q11), has not been detected in a sample.


name: Gastric Neuroendocrine Tumor Clinical Distant Metastasis TNM Finding v7

description: A clinical finding about one or more characteristics of gastric neuroendocrine tumor, following the rules of the TNM AJCC v7 classification system as they pertain to distant metastases.


name: Uterine Corpus Adenosarcoma pTX TNM Finding v8

description: Uterine corpus adenosarcoma in which the primary tumor cannot be assessed. (from AJCC 8th Ed.)


Pleural Mesothelioma pTX TNM Finding v7

description: Pleural mesothelioma in which the primary tumor cannot be assessed. (from AJCC 7th Ed.)


Grade 1 Ataxia, CTCAE

description: Asymptomatic; clinical or diagnostic observations only; intervention not indicated


Stage IVB Appendix Carcinoma AJCC v8

description: Stage IVB includes: Any T, Any N, M1b, G2, G3, or GX. M1b: Intraperitoneal metastasis only, including peritoneal mucinous deposits containing tumor cells. G2: Moderately differentiated. G3: Poorly differentiated. GX: Grade cannot be assessed.  (AJCC 8th ed.)


name: Patient's Non-Compliance with Renal Dialysis

description: Evidence of patient non-compliance with renal dialysis.


name: Malignant Neoplasm of Upper-Outer Quadrant of Left Male Breast

description: Evidence of a malignant neoplasm of the upper-outer quadrant of left male breast.


name: Metastatic Cervical Squamous Cell Carcinoma

description: Cervical squamous cell carcinoma that has spread to another anatomic site.


name: Non-Neoplastic Trigeminal Nerve Disorder

description: A non-neoplastic disorder affecting the trigeminal nerve.


name: Serum Soluble Fas Ligand Level Increased

description: An indication that the concentration of soluble Fas ligand in a sample has increased when compared to a normal baseline or a previous sample measurement.


Neonatal Culture Negative Sepsis, AE

description: An adverse event in a newborn characterized by a systemic inflammatory response without identifiable cause.


Grade 4 Tracheal Mucositis, CTCAE

description: Life-threatening consequences; urgent intervention indicated


name: Malignant neoplasm of bone and articular cartilage of limb, unspecified

description: Evidence of a malignant neoplasm of unspecified bones and articular cartilage of limb.


name: Stage II Childhood Malignant Kidney Neoplasm Excluding Renal Cell Carcinoma by Toronto Guidelines v2, Children's Oncology Group (COG) Protocol

description: Tumor extends beyond kidney but completely resected. Tumor penetrates renal capsule. Tumor in lymphatics or veins of renal sinus. Tumor in renal vein with margin not involved. No nodal or hematogenous metastases. Negative margins. (Childhood cancer staging for population registries according to the Toronto Childhood Cancer Stage Guidelines - Version 2. Cancer Council Queensland and Cancer Australia: Brisbane, Australia; 2021.)


Cannabis abuse, in remission

description: Evidence of cannabis abuse, in remission.


name: Major Salivary Gland Cancer pN0 TNM Finding v6 and v7

description: Major salivary gland cancer with no metastasis to regional lymph nodes. (from AJCC 6th and 7th Eds.)


5/10 HLA Match

description: Degree of HLA match is 5/10 for HLA-A, -B, -C, -DRB1, and -DQB1 loci.


name: Unresectable Malignant Peripheral Nerve Sheath Tumor

description: A malignant peripheral nerve sheath tumor that is not amenable to surgical resection.


Edema Trunk

description: Swelling due to an excessive accumulation of fluid in trunk area.


Pelvic Floor Disorders

description: A disorder affecting the muscles of the pelvic floor.


name: Overlapping malignant neoplasm of small intestine

description: Evidence of a malignant neoplasm of overlapping sites of the small intestine.


name: FIGO Stage IV Gestational Trophoblastic Tumor

description: Gestational trophoblastic tumor in all other metastatic sites.


name: Grade 2 Middle Ear Infection with Unknown Absolute Neutrophil Count, CTCAE


name: Unspecified inflammatory spondylopathy, thoracolumbar region

description: Evidence of unspecified inflammatory spondylopathy in the thoracolumbar region.


Grade 3 Oropharyngeal Pain, CTCAE

description: Severe pain; severely altered eating/swallowing; narcotics initiated; requires parenteral nutrition


name: Papillary, Follicular, Hurthle Cell, Poorly Differentiated, and Anaplastic Thyroid Carcinoma pT4a TNM Finding v8

description: Gross extrathyroidal extension invading subcutaneous soft tissues, larynx, trachea, esophagus, or recurrent laryngeal nerve from a tumor of any size. (from AJCC 8th Ed.)


Focal KATP-Associated Hyperinsulinism

description: KATP-associated hyperinsulinism in which there is an area of adenomatous beta-cell hyperplasia. This condition results from paternal recessive mutation(s) in either the ABCC8 or the KCNJ11 gene and paternal uniparental isodisomy of chromosome region 11p15 with loss of tumor suppressor genes expressed from the maternally inherited chromosome.


name: Ungual Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


name: Other Pre-Existing Diabetes Mellitus in Pregnancy, Unspecified Trimester

description: Evidence of other pre-existing diabetes mellitus in pregnancy in an unspecified trimester not specified elsewhere.


name: Oropharyngeal (p16-Negative) Cancer pN1 TNM Finding v8

description: Oropharyngeal (p16-negative) cancer with metastasis in a single ipsilateral lymph node, 3 cm or smaller in greatest dimension and ENE (-). (from AJCC 8th Ed.)


Dialysis Access Complication

description: Any issue that arises as a consequence of a problem with a patient's dialysis access.


Serum CA 19-9 Low

description: The amount of cancer antigen 19-9 present in a serum sample is low.


Primary Cause of Death

description: The first significant event which ultimately led to death.


Vision Decreased, CTCAE

description: A disorder characterized by a decrease in visual acuity.


name: Neck Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils NOS, CTCAE


Grade 4 Jejunal Hemorrhage, CTCAE

description: Life-threatening consequences; urgent intervention indicated


Ovarian Infection, CTCAE

description: A disorder characterized by an infectious process involving the ovary.


Locally Advanced High Grade Sarcoma

description: High-grade sarcoma that has spread from its original site of growth to nearby tissues or lymph nodes.


name: Benign Childhood Central Nervous System Neoplasm

description: A childhood neoplasm that arises from the central nervous system and is characterized by the absence of atypical or malignant cytological and architectural features, and absence of invasive features or metastatic potential.


name: Lymphocyte-Depleted Classic Hodgkin Lymphoma, Lymph Nodes of Head, Face, and Neck

description: Evidence of lymphocyte-depleted classic Hodgkin lymphoma in the lymph nodes of head in the face in the and neck.


name: Stage II Non-Contiguous Adult Diffuse Small Cleaved Cell Lymphoma

description: Stage II: Involvement of two or more lymph node regions on the same side of the diaphragm (II) or localized involvement of a single associated extralymphatic organ or site and its regional lymph nodes with or without other lymph node regions on the same side of the diaphragm (IIE). Note: The number of lymph node regions involved may be indicated by a subscript (e.g., II3). (from PDQ)


Enteric campylobacteriosis

description: A gastrointestinal infection attributed to the bacteria campylobacter. It is usually contracted by consuming raw or undercooked poultry or consuming a food that has been in contact with raw poultry. It is characterized by abdominal pain, fever, and  diarrhea and usually resolves in two to five days.


name: Gastric Cancer Pathologic Regional Lymph Nodes TNM Finding v6

description: A pathologic finding about one or more characteristics of gastric cancer, following the rules of the TNM AJCC v6 classification system as they pertain to staging of regional lymph nodes.


name: Cutaneous Follicular Center Lymphoma, Extranodal and Solid Organ Sites

description: Evidence of cutaneous follicular center lymphoma in the extranodal and solid organ sites.


name: Chief Complaint Present in the Afternoon

description: The chief complaint is noted to primarily occur after noon but before sunset.


name: Colorectal Neuroendocrine Tumor cM1c TNM Finding v8

description: Colorectal neuroendocrine tumor with both hepatic and extrahepatic metastases. (from AJCC 8th Ed.)


name: Gastrointestinal Stromal Tumor pN1 TNM Finding v7

description: Gastrointestinal stromal tumor with regional lymph node metastasis. (from AJCC 7th Ed.)


Spinal Cord Compression, CTCAE

description: A disorder characterized by pressure on the spinal cord.


name: Grade 1 Vas Deferens Stricture or Stenosis, CTCAE


name: FIGO Stage IIIB Gestational Trophoblastic Tumor


Incomplete Response/Stable Disease

description: Persistence of one or more non-target lesions.


name: Maxillary Sinus Cancer pMX TNM Finding v6

description: Maxillary sinus cancer in which distant metastasis cannot be assessed. (from AJCC 6th Ed.)


name: Diabetes Mellitus due to Underlying Condition with Moderate Non-Proliferative Diabetic Retinopathy without Macular Edema, Right Eye

description: Evidence of diabetes mellitus due to underlying condition with moderate non-proliferative diabetic retinopathy without macular edema in the right eye.


Rhinovirus infection

description: An infectious process caused by rhinovirus. The virus usually causes upper respiratory infections, but can infect the lower tract as well.


Gradient Digitization Error Artifact

description: An artifact that results from a gradient which is not constant with respect to the gradient direction.


name: Type 1 Diabetes Mellitus with Moderate Nonproliferative Diabetic Retinopathy with Macular Edema, Bilateral

description: Evidence of type 1 diabetes mellitus with moderate nonproliferative diabetic retinopathy with macular edema that is bilateral.


Stage IVB Vulvar Cancer AJCC v6 and v7

description: Stage IVB includes: Any T, Any N, M1.  M1: distant metastasis (including pelvic lymph node metastasis).  (AJCC 6th and 7th eds.)


Exposed to COVID-19

description: A finding indicating that an individual has been exposed to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).


Hemophilus influenza infection

description: An infection that is caused by the organism Hemophilus influenza.


name: Recurrent Adult Diffuse Mixed Cell Lymphoma

description: The reemergence of adult diffuse mixed cell lymphoma after a period of remission.


name: Grade 2 Other Dermatology or Skin, CTCAE


name: Cerebral Infarction due to Embolism of Unspecified Precerebral Artery

description: Evidence of cerebral infarction due to an embolism of an unspecified precerebral artery.


name: Cutaneous Squamous Cell Carcinoma of the Head and Neck Pathologic Distant Metastasis TNM Finding v8

description: A pathologic finding about one or more characteristics of cutaneous squamous cell carcinoma of the head and neck, following the rules of the TNM AJCC v8 classification system as they pertain to distant metastases.


name: Grade 2 Esophagus Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


Refractory Carcinoma

description: A carcinoma that does not respond to treatment.


name: Other Specified Diabetes Mellitus with Diabetic Nephropathy

description: Evidence of other specified diabetes mellitus with diabetic nephropathy not specified elsewhere.


name: Alcohol Abuse with Unspecified Alcohol-Induced Disorder

description: Evidence of alcohol abuse with unspecified alcohol-induced disorder.


Multifocal Glioblastomas

description: The occurrence of multiple and independent glioblastomas that are unrelated to inherited neoplastic syndromes.


name: Grade 3 Pancreas Exocrine Enzyme Deficiency, CTCAE


name: Metastatic Digestive System Neuroendocrine Tumor G3

description: Digestive system neuroendocrine tumor G3 that has spread from its original site of growth to another anatomic site.


Grade 3 Gastric Anastomotic Leak, CTCAE

description: Severe symptoms; invasive intervention indicated


Gastroenteritis enteroviral

description: Gastroenteritis resulting from an infection with enterovirus.


name: Grade 4 Peristomal Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


Grade 2 Hypoglycemia, CTCAE

description: <55-40 mg/dL; <3.0-2.2 mmol/L


Intraoperative Cardiac Injury, CTCAE

description: A finding of damage to the heart during a surgical procedure.


name: Mucosal Melanoma of the Head and Neck pT4a TNM Finding v7

description: Mucosal melanoma of the head and neck with moderately advanced disease.  Tumor involves deep soft tissue, cartilage, bone, or overlying skin. (from AJCC 7th Ed.)


name: Merkel Cell Carcinoma cN2 TNM Finding v7

description: Merkel cell carcinoma in transit metastasis.  In transit metastasis is defined as a tumor distinct from the primary lesion and located either (1) between the primary lesion and the draining regional lymph nodes or (2) distal to the primary lesion. (from AJCC 7th Ed.)


name: Grade 3 Slipped Capital Femoral Epiphysis, CTCAE


name: Grade 4 Allergic Reaction and Hypersensitivity Including Drug Fever, CTCAE


name: Melanoma in situ of right upper eyelid, including canthus

description: Evidence of melanoma in situ of right upper eyelid including the canthus.


Accelerated Phase Primary Myelofibrosis

description: Rapid progression of primary myelofibrosis, characterized by the presence of myeloblasts accounting for 10-19% of the peripheral blood white cells or the nucleated cells in the bone marrow.


name: Colorectal Neuroendocrine Tumor pM1b TNM Finding v8

description: Colorectal neuroendocrine tumor with metastasis in at least one extrahepatic site (e.g., lung, ovary, nonregional lymph node, peritoneum, bone). (from AJCC 8th Ed.)


Vulvar Cancer pN2c TNM Finding v7

description: Vulvar cancer with lymph node metastasis with extracapsular spread. (from AJCC 7th Ed.)


Accelerated Neoplasm Growth

description: Neoplasm that is growing at a faster rate


opioid dependence with intoxication

description: Evidence of opioid dependence with intoxication.


name: Lip and Oral Cavity Cancer pT4 TNM Finding v6

description: Lip cancer with tumor invading through cortical bone, inferior alveolar nerve, floor of mouth or skin of face (i.e. chin or nose). Superficial erosion of bone or tooth socket by a gingival primary tumor is not sufficient to classify as T4. (from AJCC 6th Ed.)


Grade 4 Ileal Ulcer, CTCAE

description: Life-threatening consequences; urgent operative intervention indicated


name: Diseases of the Nervous System Complicating Childbirth

description: Evidence of diseases of the nervous system complicating childbirth.


name: Spinal Cord Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


name: Resectable Platinum-Resistant Malignant Germ Cell Tumor

description: A platinum-resistant malignant germ cell tumor that is amenable to surgical resection.


Colorectal Cancer cM1b TNM Finding v8

description: Colorectal cancer with metastasis to two or more sites or organs without peritoneal metastasis. (from AJCC 8th Ed.)


name: Childhood Favorable Prognosis Hodgkin Lymphoma

description: A Hodgkin lymphoma with favorable prognosis that occurs during childhood.


name: Hepatocellular Carcinoma Pathologic Regional Lymph Nodes TNM Finding v8

description: A pathologic finding about one or more characteristics of hepatocellular carcinoma, following the rules of the TNM AJCC v8 classification system as they pertain to staging of regional lymph nodes.


Swelling

description: Enlargement; expansion in size; sign of inflammation


name: Carcinoma in Situ of Skin of Right Lower Eyelid, Including Canthus

description: Evidence of carcinoma in situ of the skin of right lower eyelid including the canthus.


name: Dravet syndrome, intractable, with status epilepticus

description: Evidence of Dravet syndrome, with status epilepticus that does not respond optimally to treatment.


Grade 1 Hypokalemia, CTCAE

description: <LLN-3.0 mmol/L


Grade 2 Pharyngitis, CTCAE

description: Oral intervention indicated (e.g., antibiotic, antifungal, or antiviral)


name: Grade 4 Thoracodorsal Nerve Intra-Operative Injury, CTCAE


name: Malignant Neoplasm of Unspecified Kidney, Except Renal Pelvis

description: Evidence of a malignant neoplasm of an unspecified kidney, except renal pelvis.


name: Gallbladder Cancer pNX TNM Finding v6 and v7

description: Gallbladder cancer in which the regional lymph nodes cannot be assessed. (from AJCC 6th and 7th Eds.)


Penile Cancer Clinical TNM Finding v8

description: A clinical finding about one or more characteristics of penile cancer, following the rules of the TNM AJCC v8 classification system.


Grade 1 Bruising, CTCAE

description: Localized or in a dependent area


Grade 3 Renal Calculi, CTCAE

description: Hospitalization indicated; IV intervention (e.g., analgesics, antiemetics); elective invasive intervention indicated


Grade 4 Fracture, CTCAE

description: Life-threatening consequences; urgent intervention indicated


Advanced Gallbladder Carcinoma

description: Gallbladder carcinoma that has spread extensively to other anatomic sites or is no longer responding to treatment.


Vasculitis, CTCAE

description: A disorder characterized by inflammation involving the wall of a vessel.


name: Type 2 Diabetes Mellitus with Moderate Nonproliferative Diabetic Retinopathy with Macular Edema, Bilateral

description: Evidence of type 2 diabetes mellitus with moderate nonproliferative diabetic retinopathy with macular edema that is bilateral.


name: Grade 2 Thorax Soft Tissue Necrosis, CTCAE


name: Prostate Carcinoma by Gene Expression Profile

description: A header term that includes the following prostate carcinoma subtypes determined by gene expression profiling: luminal A prostate carcinoma, luminal B prostate carcinoma, and basal-like prostate carcinoma.


name: Uterine Corpus Adenosarcoma Pathologic Regional Lymph Nodes TNM Finding v8

description: A pathologic finding about one or more characteristics of uterine corpus adenosarcoma, following the rules of the TNM AJCC v8 classification system as they pertain to staging of regional lymph nodes.


Prostatic Basal Cell Hyperplasia

description: A type of prostatic hyperplasia.  It is characterized by the presence of nodules of dark basal cells around residual prostatic secretory cells.


name: Exocrine Pancreatic Cancer pTX TNM Finding v6

description: Exocrine pancreatic cancer in which the primary tumor cannot be assessed. (from AJCC 6th Ed.)


name: Recurrent Acute Myeloid Leukemia Not Otherwise Specified

description: The reemergence of acute myeloid leukemia not otherwise specified after a period of remission.


name: Adrenal Cortical Carcinoma pT3 TNM Finding v8

description: Tumor of any size with local invasion but not invading adjacent organs. (from AJCC 8th Ed.)


name: Vein Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


name: Unspecified Atherosclerosis of Native Arteries of Extremities, Right Leg

description: Evidence of unspecified atherosclerosis of native arteries of extremities in the right leg.


Grade 2 Vaginal Inflammation, CTCAE

description: Moderate discomfort or pain, edema, or redness; limiting instrumental ADL


Benign neoplasm of cranial nerves

description: A neoplasm that arises from a cranial nerve and is characterized by the absence of atypical or malignant cytological and architectural features, and absence of invasive features or metastatic potential.


name: Refractory Acute Leukemia of Ambiguous Lineage

description: Acute leukemia of ambiguous lineage that is resistant to treatment.


Cutting Behavior

description: Self-injury caused by making cuts into the skin.


name: Grade 5 Otitis Middle Ear Non Infectious, CTCAE


name: Grade 2 Testis Intra-Operative Injury, CTCAE


name: Grade 1 Nodal or Junctional Rhythm, CTCAE


name: Grade 2 Trigeminal Nerve Disorder, CTCAE

description: Moderate symptoms; limiting instrumental ADL


Childhood Giant Cell Glioblastoma

description: A giant cell glioblastoma that occurs during childhood.


Subretinal Seeding

description: Tumor seeding that is localized under the retina.


Syphilitic endocarditis

description: Endocarditis secondary to syphilis.


name: Grade 4 Soft Tissue Infection NOS with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


name: Grade 4 Stomach Mucositis or Stomatitis by Functional or Symptomatic Classification, CTCAE


Esophageal Perforation, CTCAE

description: A disorder characterized by a rupture in the wall of the esophagus.


Non-Neoplastic Retinal Disorder

description: A non-neoplastic disorder that affects the retina.


name: Monoplegia of Lower Limb following Cerebral Infarction Affecting Unspecified Side

description: Evidence of monoplegia of lower limb following cerebral infarction affecting unspecified side.


name: Grade 1 Other Constitutional Symptoms, CTCAE


Grade 2 Urostomy Leak, CTCAE

description: Symptomatic; medical intervention indicated


Grade 3 Chest Pain - Cardiac, CTCAE

description: Pain at rest; limiting self care ADL; cardiac catheterization; new onset cardiac chest pain; unstable angina


description: The reemergence of a myelodysplastic/myeloproliferative neoplasm after a period of remission.


Grade 3 Pharyngolaryngeal Pain, CTCAE

description: Severe pain; limiting self care ADL


name: Childhood Acute Myeloid Leukemia Not Otherwise Specified

description: Acute myeloid leukemias that occur in childhood and do not fulfill the criteria for inclusion in the group of acute myeloid leukemias which have recurrent genetic abnormalities or myelodysplastic changes, or are therapy-related.  This category includes entities classified according to the French-American-British classification scheme.


Cervical Blue Nevus

description: A nevus that arises from the cervix. It is characterized by the presence of benign, heavily pigmented dendritic melanocytes.


cocaine dependence with withdrawal

description: Evidence of cocaine dependence with withdrawal.


Retinoblastoma pT3 TNM Finding v8

description: Intraocular tumor(s) with significant local invasion. (from AJCC 8th Ed.)


Grade 3 Bile Duct Stenosis, CTCAE

description: Severely altered GI function; invasive intervention indicated


name: Grade 4 Artery Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


name: Heart Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


name: Dyspnea with No Physical Activity Limitation

description: Dyspnea that does not interfere with their physical activity.


description: Gastritis that is characterized by erosion of the mucosal surface.


name: Hypopharyngeal Cancer cN2 TNM Finding v8

description: Hypopharyngeal cancer with metastasis in a single ipsilateral lymph node larger than 3 cm but not larger than 6 cm in greatest dimension and ENE(-); or metastases in multiple ipsilateral lymph nodes, none larger than 6 cm in greatest dimension and ENE(-); or metastases in bilateral or contralateral lymph nodes, none larger than 6 cm in greatest dimension and ENE(-). (from AJCC 8th Ed.)


Cotinine Less than 10 ng/ml

description: A semiquantitative finding indicating that the concentration of cotinine in a sample is less than 10 ng/mL.


Congenital Disruption

description: A morphologic defect of an organ, part of an organ, or a larger region of the body that results from the extrinsic breakdown of, or an interference with, an originally normal developmental process.


Malignant Neoplasm of Right Conjunctiva

description: Evidence of a malignant neoplasm of the right conjunctiva.


name: Ocular Adnexal Lymphoma pN2 TNM Finding v7

description: Involvement of contralateral or bilateral regional lymph nodes.  Note: The regional lymph nodes include preauricular (parotid), submandibular, and cervical. (from AJCC 7th Ed.)


Transient Organic Mental Disorder

description: An organic mental disorder that is temporary in nature.


Elevated CA15-3

description: A laboratory test result indicating the presence of an increased level of the tumor-associated antigen (TAA) CA15-3 in a blood or serum sample.


name: Gallbladder Cancer Pathologic TNM Finding v8

description: A pathologic finding about one or more characteristics of gallbladder cancer, following the rules of the TNM AJCC v8 classification system.


name: Secondary malignant neoplasm of intrathoracic lymph nodes

description: Evidence of secondary and unspecified malignant neoplasm of intrathoracic lymph nodes.


Delayed Capillary Refill Time

description: A clinical finding in which a capillary nail refill test returns to pink color in greater than two seconds after pressure is removed. (ACC/AHA)


Jaccoud Arthropathy, Right Wrist

description: Evidence of Jaccoud arthropathy in the right wrist.


Small Intestinal Obstruction, CTCAE

description: A disorder characterized by blockage of the normal flow of the intestinal contents of the small intestine.


Grade 5 Bronchopleural Fistula, CTCAE

description: Death


Grade 4 Atrial Flutter, CTCAE

description: Life-threatening consequences; embolus requiring urgent intervention


Atrial Septum Lipomatous Hypertrophy

description: A condition in which deposits of fat accumulate within the interatrial septum.


name: EBV-Related Clonal Post-Transplant Lymphoproliferative Disorder

description: A clonal lymphoproliferative disorder that develops following organ transplantation and is associated with Epstein-Barr virus infection.


Other Classic Hodgkin Lymphoma, Spleen

description: Evidence of other classic Hodgkin lymphoma in the spleen not specified elsewhere.


name: Shared Neoantigen-Positive Malignant Solid Neoplasm

description: A malignant solid neoplasm that expresses unique tumor-specific neoantigens across a subset of patients.


name: Grade 1 Pharynx Mucositis or Stomatitis by Clinical Examination Classification, CTCAE


Radiation-Related Sarcoma

description: A sarcoma that arises in the bones or soft tissues following exposure to ionizing or non-ionizing radiation.


Carcinoma in situ of hard palate

description: Evidence of carcinoma in situ of the hard palate.


PSA Level Zero to Forty Four

description: A blood concentration of prostate specific antigen between 0 ng/mL and 44 ng/mL.


name: Recurrent Chronic Myelomonocytic Leukemia

description: The reemergence of chronic myelomonocytic leukemia after a period of remission.


Iron Overload, CTCAE

description: A disorder characterized by accumulation of iron in the tissues.


NF1 Gene Mutation Negative

description: A genetic finding indicating that NF1 gene mutations have not been detected in a sample.


Appendix Neuroendocrine Tumor G2

description: A well differentiated, intermediate grade neoplasm with neuroendocrine differentiation that arises from the appendix. The mitotic count is 2-20 per 10 HPF and/or the Ki67 index is 3 to 20 percent.


Grade 5 Rectal Necrosis, CTCAE

description: Death


Clinical Primary Tumor TNM Finding

description: A clinical finding about one or more characteristics of a specific cancer, following the rules of the TNM classification system as they pertain to evaluating primary tumor.


Grade 1 Ileal Stenosis, CTCAE

description: Asymptomatic; clinical or diagnostic observations only; intervention not indicated


Grade 3 Glucose Intolerance, CTCAE

description: Severe symptoms; insulin indicated


Acute duodenal ulcer with perforation

description: Evidence of an acute duodenal ulcer with perforation.


Grade 1 Prostatic Hemorrhage, CTCAE

description: Mild symptoms; intervention not indicated


name: Nasal Cavity and Ethmoid Sinus Cancer Pathologic TNM Finding v6

description: A pathologic finding about one or more characteristics of nasal cavity and ethmoid sinus cancer, following the rules of the TNM AJCC v6 classification system.


Menorrhagia, CTCAE

description: A disorder characterized by abnormally heavy vaginal bleeding during menses.


Gene Variant Negative

description: An indication that gene variants were not detected in a sample.


name: Rheumatoid Arthritis of Left Ankle and Foot with Involvement of Organs and Systems

description: Evidence of rheumatoid arthritis of left ankle and foot with involvement of organs and systems.


Rheumatoid Nodule, Right Shoulder

description: Evidence of rheumatoid nodule in the right shoulder.


Stage IA1 Cervical Cancer AJCC v9

description: Stage IA1 includes: T1a1, N0, M0. T1a1: Tumor with measured stromal invasion equal or less than 3 mm in depth. N0: No regional lymph node metastasis. M0: No distant metastasis. (from AJCC 9th Ed.)


Grade 2 Duodenal Stenosis, CTCAE

description: Symptomatic; altered GI function


name: Malignant Neoplasm of Overlapping Sites of Left Bronchus and Lung

description: Evidence of a malignant neoplasm of overlapping sites of the left bronchus and lung.


Grade 4 Hypertriglyceridemia, CTCAE

description: >1000 mg/dL; >11.4 mmol/L; life-threatening consequences


Grade 2 Urinary Tract Infection, CTCAE

description: Localized; oral intervention indicated (e.g., antibiotic, antifungal, or antiviral)


Grade 2 Confusion, CTCAE

description: Moderate disorientation; limiting instrumental ADL


Grade 2 Papilledema, CTCAE

description: Symptomatic; moderate decrease in visual acuity (best corrected visual acuity 20/40 and better or 3 lines or less decreased vision from known baseline)


name: Primary Cutaneous B-Cell/T-Cell (Non-MF/SS) Lymphoma T2a TNM Finding v8

description: All disease encompassing in a less than 15-cm circular area. (from AJCC 8th Ed.)


name: Acute Myeloid Leukemia with t(3;12)(q26.2;p13.2); ETV6-MECOM

description: An acute myeloid leukemia associated with t(3;12)(q26.2;p13.2) resulting in the expression of ETV6-MECOM fusion gene.


Morphologic Complete Response

description: The disappearance of all signs of cancer, supported by morphological analysis.


Grade 3 Restlessness, CTCAE

description: Severe symptoms; limiting self care ADL


name: Advanced Gastric Neuroendocrine Carcinoma

description: A gastric neuroendocrine carcinoma that has spread extensively to other anatomic sites or is no longer responding to treatment.


name: Unspecified Atherosclerosis of Non-Biological Bypass Graft(s) of the Extremities, Unspecified Extremity

description: Evidence of unspecified atherosclerosis of non-biological bypass graft(s) of the extremities in an unspecified extremity.


name: Malignant Neoplasm of Lower-Inner Quadrant of Right Female Breast

description: Evidence of a malignant neoplasm of the lower-inner quadrant of right female breast.


name: Adrenal Cortical Carcinoma Clinical Distant Metastasis TNM Finding v8

description: A clinical finding about one or more characteristics of adrenal cortical carcinoma, following the rules of the TNM AJCC v8 classification system as they pertain to distant metastases.


name: Grade 2 Endocrine Disorders - Other, Specify, CTCAE

description: Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL


name: Melanoma of the Conjunctiva pT1c TNM Finding v7

description: Melanoma of the bulbar conjunctiva with tumor measuring more than 1.5 mm in thickness with invasion of the substantia propria.  (from AJCC 7th Ed.)


Connective and Soft Tissue Disorder

description: A non-neoplastic or neoplastic disorder that affects the connective and soft tissue.


Grade 1 Pneumonitis, CTCAE

description: Asymptomatic; clinical or diagnostic observations only; intervention not indicated


7/10 HLA Match

description: Degree of HLA match is 7/10 for HLA-A, -B, -C, -DRB1, and -DQB1 loci.


name: Cutaneous Melanoma Clinical Regional Lymph Nodes TNM Finding v8

description: A clinical finding about one or more characteristics of cutaneous melanoma, following the rules of the TNM AJCC v8 classification system as they pertain to staging of regional lymph nodes. The TNM clinical and pathologic regional lymph nodes classifications of cutaneous melanoma are not the same. TNM clinical regional lymph nodes findings are based on clinical/radiographic examination of the regional lymph nodes (clinically detected regional lymph node metastasis). (from AJCC 8th Ed.)


name: Metastatic Proximal Gastric Adenocarcinoma

description: A proximal gastric adenocarcinoma that has spread from its original site of growth to another anatomic site.


Grade 1 Sneezing, CTCAE

description: Mild symptoms; intervention not indicated


Adenosarcoma pT1a TNM Finding v7

description: Tumor limited to endometrium/endocervix. (from AJCC 7th Ed.)


name: Skin Basal Cell Carcinoma with Adnexal Differentiation

description: A basal cell carcinoma of the skin that is characterized by adnexal differentiation.


name: Diffuse Follicular Center Lymphoma, Lymph Nodes of Inguinal Region and Lower Limb

description: Evidence of diffuse follicular center lymphoma, lymph nodes of inguinal region and lower limb.


name: Central Nervous System Histiocytic and Dendritic Cell Neoplasm

description: A neoplasm that originates from histiocytes and accessory cells and affects the central nervous system.  It is usually associated with the presence of identical tumors outside the central nervous system.  Representative examples include Langerhans cell histiocytosis, histiocytic sarcoma, and follicular dendritic cell sarcoma.


Spiculated Nodule

description: The presence of two or more linear opacities extending from the nodule margin that taper as their distance from the nodule increases. Use tapering to distinguish from external septal stretching.


MAP2K1 Gene Mutation Negative

description: A genetic finding indicating that MAP2K1 gene mutations have not been detected in a sample.


Grade 5 Stroke, CTCAE

description: Death


Lesion by Focality

description: A term referring to the number of anatomic sites affected by a disease.


name: Parathyroid Carcinoma pTX TNM Finding v8

description: Primary tumor cannot be assessed. (from AJCC 8th Ed.)


Pharyngolaryngeal Pain

description: Painful sensation in the pharyngolaryngeal region.


name: Sedative, Hypnotic or Anxiolytic Abuse with Intoxication, Uncomplicated

description: Evidence of sedative, hypnotic or anxiolytic abuse with intoxication, uncomplicated.


name: Grade 3 Inferior Vena Cava Intra-Operative Injury, CTCAE


Left Bundle Branch Block Artifact

description: An imaging artifact resulting from a patient left bundle branch block.


Breast Infection, CTCAE

description: A disorder characterized by an infectious process involving the breast.


name: Grade 5 Esophagus Mucositis or Stomatitis by Clinical Examination Classification, CTCAE


Intervening Foreign Body

description: An artifact resulting from the presence of a foreign body between the target and the receiver.


name: Type 1 Diabetes Mellitus with Moderate Nonproliferative Diabetic Retinopathy without Macular Edema, Bilateral

description: Evidence of type 1 diabetes mellitus with moderate nonproliferative diabetic retinopathy without macular edema that is bilateral.


Grade 4 Uveitis, CTCAE

description: Best corrected visual acuity of 20/200 or worse in the affected eye


name: Grade 2 Anal or Perianal Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


name: Metastatic Bladder Nested Urothelial Carcinoma

description: Bladder nested urothelial carcinoma that has spread to another anatomic site.


name: Malignant Neoplasm of Lower Lobe, Left Bronchus or Lung

description: Evidence of a malignant neoplasm of the lower lobe in the left bronchus or lung.


Testosterone Less than 50 ng/dL

description: A semiquantitative finding indicating that the concentration of testosterone in a sample is less than 50 ng/dL.


name: Other Cerebral Infarction due to Occlusion or Stenosis of Small Artery

description: Evidence of other cerebral infarction due to occlusion or stenosis of small artery not specified elsewhere.


name: Perianal Squamous Intraepithelial Neoplasia

description: A precancerous neoplastic intraepithelial process involving the squamous epithelium of the perianal skin. Clinically, it usually presents as a white or red area in the perianal skin. Morphologically, it is characterized by full thickness dysplasia of the squamous epithelium and sometimes of the pilosebaceous epithelium. Human papillomavirus DNA sometimes may be identified in the dysplastic epithelium. It may recur after treatment, however only a small percentage of cases progress to squamous cell carcinoma.


Cholesterol High, CTCAE

description: A finding based on laboratory test results that indicate higher than normal levels of cholesterol in a blood specimen.


name: Post-Dysenteric Arthropathy, Unspecified Elbow

description: Evidence of post-dysenteric arthropathy in an unspecified elbow.


Infectious Mediastinitis

description: An acute or chronic infectious process affecting the mediastinum.


Cervical Cancer pT1a1 TNM Finding v9

description: Invasive cervical carcinoma with measured stromal invasion equal or less than 3 mm in depth. (from AJCC 9th Ed.)


Road Injury

description: An injury that occurs on a road or motor way.


name: cocaine abuse with intoxication with perceptual disturbances

description: Evidence of cocaine abuse with intoxication with perceptual disturbance.


name: Grade 1 Neck NOS Intra-Operative Injury, CTCAE


name: Soft Tissue Sarcoma of the Abdomen and Thoracic Visceral Organs pT1 TNM Finding v8

description: Soft tissue sarcoma of the abdomen and thoracic visceral organs, organ confined. (from AJCC 8th Ed.)


Grade 3 Vaginal Hemorrhage, CTCAE

description: Transfusion indicated; invasive intervention indicated; hospitalization


name: Grade 4 Peripheral Nerve Infection, CTCAE

description: Life-threatening consequences; urgent intervention indicated


name: Merkel Cell Polyoma Virus-Positive Merkel Cell Carcinoma

description: A Merkel cell carcinoma that is associated with Merkel cell polyoma virus infection.


name: Grade 2 Salivary Gland Intra-Operative Injury, CTCAE


Elevated Urine Alkaline Phosphatase

description: An elevated concentration of alkaline phosphatase in the urine.


Infratentorial Glioblastoma

description: A glioblastoma that occurs in the infratentorial region.


Cutaneous Melanoma pTis TNM Finding v8

description: Cutaneous melanoma with a finding of melanoma in situ. Thickness: Not applicable. Ulceration status: Not applicable. (from AJCC 8th Ed.)


name: Malignant Lymphoma Follicular, Large Cleaved Cell Type


name: Sedative, Hypnotic or Anxiolytic lnduced Dependence with withdrawal with Perceptual Disturbance

description: Evidence of sedative, hypnotic or anxiolytic induced dependence with withdrawal with perceptual disturbance.


name: Partial occlusion of left retinal artery

description: Evidence of partial retinal artery occlusion in the left eye.


name: Rheumatoid Vasculitis with Rheumatoid Arthritis of Right Hand

description: Evidence of rheumatoid vasculitis with rheumatoid arthritis of right hand.


Scrotal Pain, CTCAE 5.0

description: A disorder characterized by a sensation of marked discomfort in the scrotal area.


name: Merkel Cell Carcinoma Pathologic TNM Finding v7

description: A pathologic finding about one or more characteristics of Merkel cell carcinoma, following the rules of the TNM AJCC v7 classification system. TNM pathologic findings are based on the histologic examination of the regional lymph nodes following focused (sentinel lymph node biopsy), therapeutic, or complete lymphadenectomy.  (from AJCC 7th Ed.)


Mild recurrent major depression

description: Evidence of major depressive disorder that is recurrent and mild.


name: Grade 5 Esophagus Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


name: Mixed Epithelial and Mesenchymal Hair Follicle Neoplasm

description: A trichoblastoma characterized by the presence of neoplastic epithelial cell forming nodules. There are palisaded basaloid cells present at the periphery and pale larger cells with vesicular nuclei, prominent nucleoli, and abundant cytoplasm present at the center of the nodules. The epithelial cells are admixed with numerous small lymphocytes and occasional large multinucleated cells that resemble Reed-Sternberg cells.


Urine Output Decreased, CTCAE

description: A finding based on test results that indicate urine production is less relative to previous output.


name: Congenital Abnormalities of Erythrocyte Differentiation or Function

description: Inherited disorders involving abnormalities of red blood cell function, structure, or production. Some diseases in this group may be associated with bone marrow failure, neutropenia, and/or thrombocytopenia.


name: Metastatic malignant neoplasm to bone marrow

description: The spread of a malignant neoplasm from its original site of growth to the bone marrow.


name: Atherosclerosis of Non-Autologous Biological Bypass Graft(s) of the Extremities with Intermittent Claudication, Unspecified Extremity

description: Evidence of atherosclerosis of non-autologous biological bypass graft(s) of the extremities with intermittent claudication, unspecified extremity.


47,XYY Karyotype

description: An abnormal sex chromosome karyotype where the individual has one X chromosome and has two copies of the Y chromosome. The normal autosomal karyotype is present.


name: Utricle-Associated Mucosal Gland Hyperplasia

description: A benign microacinar proliferation occurring exclusively in the area of the utricle.


Acquired Cytomegaloviral Infection

description: An infection with the Cytomegalovirus that is not present from birth.


name: Grade 2 Small Intestine Infection, CTCAE

description: Moderate symptoms; oral intervention indicated (e.g., antibiotic, antifungal, or antiviral)


Biliary System Disorder

description: A non-neoplastic or neoplastic disorder that affects the intrahepatic or extrahepatic bile ducts or the gallbladder. Representative examples of non-neoplastic disorders include cholangitis and cholecystitis. Representative examples of neoplastic disorders include extrahepatic bile duct adenoma, intrahepatic and extrahepatic cholangiocarcinoma, and gallbladder carcinoma.


Increased Concomitant Drug Level

description: An increase in the level of a concomitant drug.


Adrenal Gland Hyperplasia II

description: Decreased activity of the enzyme 3-beta-hydroxysteroid dehydrogenase, associated with mutation(s) in the HSD3B2 gene. The lack of activity of this enzyme produces a type of congenital adrenal hyperplasia.


name: Grade 2 Skin Infection with Unknown Absolute Neutrophil Count, CTCAE


name: Grade 2 Cranial Nerve IV Intra-Operative Injury, CTCAE


name: Intrahepatic Bile Duct Cancer pT3 TNM Finding v7

description: Intrahepatic bile duct cancer with tumor perforating the visceral peritoneum or involving the local extra hepatic structures by direct invasion. (from AJCC 7th Ed.)


name: Unspecified Juvenile Rheumatoid Arthritis, Right Hand

description: Evidence of unspecified juvenile rheumatoid arthritis in the right hand.


Grade 1 Intestinal Stoma Leak, CTCAE

description: Asymptomatic diagnostic finding; intervention not indicated


Grade 3 Suicide Attempt, CTCAE

description: Suicide attempt or gesture without intent to die


name: Spinal enthesopathy of thoracolumbar region

description: Evidence of spinal enthesopathy in the thoracolumbar region.


name: Grade 3 Voice Changes and Dysarthria, CTCAE


name: Type 2 Diabetes Mellitus with Proliferative Diabetic Retinopathy with Macular Edema, Right Eye

description: Evidence of type 2 diabetes mellitus with proliferative diabetic retinopathy with macular edema in the right eye.


name: Grade 3 Ureter Infection with Unknown Absolute Neutrophil Count, CTCAE


Refractory Gastric Adenocarcinoma

description: Gastric adenocarcinoma that is resistant to treatment.


name: Cranial Nerve IX Motor Intra-Operative Injury, CTCAE


name: Grade 5 Upper Aerodigestive Infection NOS with Unknown Absolute Neutrophil Count, CTCAE


Cervical Cancer cT4 TNM Finding v7

description: Cervical cancer invades mucosa of bladder or rectum, and/or extends beyond true pelvis (bullous edema is not sufficient to classify a tumor as T4). (from AJCC 7th Ed.)


Stage IV Vaginal Cancer AJCC v6 and v7

description: Stage IV includes: IVA: (T4, Any N, M0) and IVB: (Any T, Any N, M1).  T4: Tumor invades mucosa of the bladder or rectum and/or extends beyond the true pelvis (bullous edema is not sufficient evidence to classify tumor as T4).  M0: No distant metastasis.  M1: Distant metastasis.  (AJCC 6th and 7th eds.)


Rheumatoid bursitis

description: Evidence of rheumatoid bursitis in an unspecified site.


Early Stage Cervical Carcinoma

description: A stage term that refers to cervical carcinoma stages IA, IB, and IIA.


Ocular Adnexal Lymphoma TNM Finding v8

description: A finding about one or more characteristics of ocular adnexal lymphoma, following the rules of the TNM AJCC v8 classification system. The lymphomas staged according to this system are primary lymphomas arising in the ocular adnexa-namely, the conjunctiva, eyelids, lacrimal gland, lacrimal drainage apparatus, and other orbital tissues surrounding the eye. Secondary ocular adnexal lymphomas and intraocular lymphomas are staged according to the classification for Hodgkin and non-Hodgkin lymphoma. There is no prognostic stage grouping for ocular adnexal lymphomas. (from AJCC 8th Ed.)


name: Unresectable Extrapulmonary Small Cell Neuroendocrine Carcinoma

description: Extrapulmonary small cell neuroendocrine carcinoma that is not amenable to surgical resection.


name: Melanoma of the Conjunctiva pT1b TNM Finding v7

description: Melanoma of the bulbar conjunctiva with tumor measuring more than 0.5 mm but not more than 1.5 mm in thickness with invasion of the substantia propria.  (from AJCC 7th Ed.)


name: Grade 4 Ungual Infection with Unknown Absolute Neutrophil Count, CTCAE


name: Grade 5 Catheter-Related Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


name: Exocrine Pancreatic Cancer pNX TNM Finding v8

description: Exocrine pancreatic cancer in which the regional lymph nodes cannot be assessed.  (from AJCC 8th Ed.)


name: Grade 3 Skin Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


HER2/Neu Status by Immunohistochemistry

description: The result of HER2/Neu status as determined by immunohistochemical detection.


name: HPV-Mediated (p16-Positive) Oropharyngeal Cancer pT3 TNM Finding v8

description: HPV-mediated (p16-positive) oropharyngeal cancer with tumor larger than 4 cm in greatest dimension or extension to lingual surface of epiglottis. (from AJCC 8th Ed.)


Granuloma of conjunctiva

description: A granuloma located on the conjunctiva, usually involving the inner surface of the eyelid.


description: Evidence of hydrocephalus in diseases classified elsewhere.


Ankylosing spondylitis, thoracic region

description: Evidence of ankylosing spondylitis of thoracic region.


name: Appendiceal Carcinoma pTX TNM Finding v7

description: Appendiceal carcinoma in which the primary tumor cannot be assessed. (from AJCC 7th Ed.)


name: Sedative, Hypnotic or Anxiolytic Dependence with Other Disorder

description: Evidence of sedative, hypnotic or anxiolytic dependence with other disorder.


name: Grade 2 Forced Expiratory Volume Decreased, CTCAE

description: FEV1 60-69%


NRAS Negative

description: An indication that NRAS expression has not been detected in a sample.


name: Gestational Diabetes Mellitus in Pregnancy, Controlled by Oral Hypoglycemic Drugs

description: Evidence of gestational diabetes mellitus in pregnancy that is controlled by oral hypoglycemic drugs.


Terminal Hematuria

description: Gross hematuria that occurs at the end of, or immediately after voiding.


name: Grade 5 Large Bowel Mucositis or Stomatitis by Functional or Symptomatic Classification, CTCAE


Plaque-Like Lesion

description: A flat lesion resembling a plaque.


Grade 2 Ileal Obstruction, CTCAE

description: Symptomatic; altered GI function; limiting instrumental ADL; naso-gastric tube indicated


name: Unresectable Cervical Squamous Cell Carcinoma

description: Cervical squamous cell carcinoma that is not amenable to surgical resection.


name: Prostatic Clear Cell Cribriform Hyperplasia

description: A rare type of prostatic hyperplasia. It is characterized by hyperplastic glandular cells with clear cytoplasm.


Unexpected Adverse Drug Reaction

description: An adverse drug reaction, whose nature, severity, specificity, or outcome is not consistent with the term or description used in the applicable product information (e.g., IB for an unapproved investigational product or PI/summary of product characteristics for an approved product, and/or scientific literature). (ICH)


name: Grade 4 Anus Mucositis or Stomatitis by Clinical Examination Classification, CTCAE


name: Major Salivary Gland Cancer pM0 TNM Finding

description: Major salivary gland cancer with no distant metastasis. (from AJCC 6th Ed.)


name: Grade 3 Bone Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


Complete Response in Solid Tumors

description: The disappearance of all signs of solid tumors in response to treatment.


name: Merkel Cell Carcinoma pM1c TNM Finding v7

description: Merkel cell carcinoma with metastasis to all other visceral sites. (from AJCC 7th Ed.)


Induction Death

description: Death of the patient due to the toxic side effects of induction therapy.


Grade 5 Spinal Fracture, CTCAE

description: Death


name: Grade 4 Pelvis Infection NOS with Unknown Absolute Neutrophil Count, CTCAE


name: Abdomen Infection with Unknown Absolute Neutrophil Count NOS, CTCAE


Crushing injury

description: Traumatic compression of the body or a part of the body.


name: Grade 5 Other Hemorrhage and Bleeding, CTCAE


Grade 5 Esophageal Ulcer, CTCAE

description: Death


Adenosarcoma pNX TNM Finding v7

description: Regional lymph nodes cannot be assessed. (from AJCC 7th Ed.)


name: Soft Tissue Sarcoma of the Trunk and Extremities pTX TNM Finding v8

description: Soft tissue sarcoma of the trunk and extremities in which the primary tumor cannot be assessed. (from AJCC 8th Ed.)


NRAS Exon 4 Mutation Negative

description: A genetic finding indicating that NRAS exon 4 gene mutations have not been detected in a sample.


Vaginal Cancer Clinical TNM Finding v8

description: A clinical finding about one or more characteristics of vaginal cancer, following the rules of the TNM AJCC v8 classification system.


Chief Complaint Continuously Present

description: The chief complaint continues without interruption.


Grade 5 Colonic Fistula, CTCAE

description: Death


description: Evidence of opioid dependence with intoxication delirium.


Metastatic Malignant Mesothelioma

description: Malignant mesothelioma that has spread from its original site of growth to another anatomic site.


Grade 2 Fever, CTCAE

description: >39.0-40.0 degrees C (102.3-104.0 degrees F)


name: Prostate Cancer pT2c TNM Finding v6 and v7

description: Prostate cancer involving both lobes of the prostate gland. (from AJCC 6th and 7th Eds.)


name: Cerebral Infarction due to Unspecified Occlusion or Stenosis of Bilateral Posterior Cerebral Artery

description: Evidence of cerebral infarction due to an unspecified occlusion or stenosis of the bilateral posterior cerebral artery.


name: Primary malignant neoplasm of overlapping sites of cervix uteri

description: Evidence of a malignant neoplasm of overlapping sites of the cervix uteri.


name: Thyroid Cancer Pathologic Primary Tumor TNM Finding v7

description: A pathologic finding about one or more characteristics of thyroid cancer, following the rules of the TNM AJCC v7 classification system as they pertain to staging of the primary tumor.  Note: All categories may be subdivided: (s) solitary tumors and (m) multifocal tumor (the largest determines the classification) (from AJCC 7th Ed.)


Stage IA Fallopian Tube Cancer AJCC v8

description: Stage IA includes: T1a, N0, M0. T1a: Fallopian tube cancer with tumor limited to fallopian tube surface; no malignant cells in ascites or peritoneal washings N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 8th Ed.)


name: Increase in B-type Natriuretic Peptide or N-terminal pro-B-type Natriuretic Peptide

description: A finding of an increased amount of either B-type natriuretic peptide or N-terminal pro-B-type natriuretic peptide


Testicular Cancer pM1b TNM Finding v8

description: Testicular cancer with non-pulmonary visceral metastases. (from AJCC 8th Ed.)


Increased Drug AUC

description: Increased area under the plot of plasma concentration of a drug against time after drug administration.


name: Grade 3 Bronchus Infection with Unknown Absolute Neutrophil Count, CTCAE


name: Digestive System Small Cell Neuroendocrine Carcinoma

description: An aggressive, high-grade, and poorly differentiated carcinoma with neuroendocrine differentiation that arises from any part of the gastrointestinal system.  It is characterized by the presence of malignant small cells.


name: Localized Hemorrhagic and Ulcerated Lesion

description: A finding indicating the presence of a focal ulcerated lesion that is associated with hemorrhage.


Early Localized Lyme Disease

description: An early stage of Lyme disease that may present within 3-30 days after a tick bite with a red, concentrically-expanding rash (erythema migrans), fatigue, chills, fever, headache, muscle and joint aches, and swollen lymph nodes.


Receptor Status

description: Refers to the presence or absence of specific receptor molecules on the surface of a cells in a specimen.


name: Nasopharyngeal Cancer pNX TNM Finding v8

description: Nasopharyngeal cancer in which the regional lymph nodes cannot be assessed. (from AJCC 8th Ed.)


PSA Level Less than or Equal to Ten

description: A blood concentration of prostate specific antigen less than or equal to 10 ng/mL.


Deficiency of vitamin D3

description: Abnormally low concentration of vitamin D3 (cholecalciferol) in the blood.


PSA Level Less than Twenty Five

description: A blood concentration of prostate specific antigen less than 25 ng/mL.


Cutaneous Melanoma pT1b TNM Finding v7

description: Cutaneous melanoma with a tumor measuring 1.0 mm or less in thickness, with ulceration or mitoses equal to or more than 1/mm2. (from AJCC 7th Ed.)


name: Grade 2 Radiation Excluding Chemoradiation, CTCAE


name: Opioid Use, Unspecified with Opioid-Induced Psychotic Disorder, Unspecified

description: Evidence of opioid use, unspecified with opioid-induced psychotic disorder.


Arteriovenous fistula thrombosis

description: Partial or complete occlusion of the lumen within an arteriovenous fistula by a thrombus.


Stage IIIA Anal Cancer AJCC v8

description: Stage IIIA includes: (T1, N1, M0); (T2, N1, M0). T1: Tumor 2 cm or smaller. T2: Tumor larger than 2 cm but equal to or smaller than 5 cm. N1: Metastasis in inguinal, mesorectal, internal iliac, or external iliac nodes. M0: No distant metastasis. (AJCC 8th ed.)


name: Grade 1 Gastrointestinal Disorders - Other, Specify, CTCAE

description: Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated


Grade 1 Ileal Ulcer, CTCAE

description: Asymptomatic; clinical or diagnostic observations only; intervention not indicated


name: Grade 2 Cranial Nerve III Neuropathy, CTCAE


Grade 4 Pleural Hemorrhage, CTCAE

description: Life-threatening consequences; intubation or urgent intervention indicated


Neonatal Culture Positive Sepsis, AE

description: An adverse event in a newborn characterized by a systemic inflammatory response to an infection with an identifiable cause.


name: Locally Advanced Small Cell Neuroendocrine Carcinoma

description: A small cell neuroendocrine carcinoma that has spread from its original site of growth to nearby tissues or lymph nodes.


Benign Hair Follicle Neoplasm

description: A neoplasm that arises from the hair follicle and is characterized by the absence of atypical or malignant cytological and architectural features, and absence of invasive features or metastatic potential.


name: Hypopharyngeal Cancer cN2b TNM Finding v8

description: Hypopharyngeal cancer with metastases in multiple ipsilateral lymph nodes, none larger than 6 cm in greatest dimension and ENE(-). (from AJCC 8th Ed.)


name: Ovarian, Fallopian Tube, and Primary Peritoneal Carcinoma pT1 TNM Finding v8

description: Ovarian, fallopian tube, or primary peritoneal carcinoma with tumor limited to ovaries (one or both) or fallopian tube(s). (from AJCC 8th Ed.)


Colorectal Cancer pN2 TNM Finding v6

description: Colorectal cancer with metastasis in four or more regional lymph nodes. (from AJCC 6th Ed.)


Childhood Breast Neoplasm

description: A neoplasm that affects the breast and occurs during childhood.


name: Merkel Cell Carcinoma pN1 TNM Finding v7

description: Merkel cell carcinoma with metastasis in regional lymph node(s). (from AJCC 7th Ed.)


name: Major Salivary Gland Cancer pN2 TNM Finding v6 and v7

description: Major salivary gland cancer with metastasis in a single ipsilateral lymph node, more than 3 cm but not more than 6 cm in greatest dimension, or in multiple ipsilateral lymph nodes, none more than 6 cm in greatest dimension, or in bilateral or contralateral lymph nodes, none more than 6 cm in greatest dimension. (from AJCC 6th and 7th Eds.)


Enzyme Secretion Alteration

description: A finding indicating a deficiency or excess in secretion of one or more enzymes.


name: Grade 4 Scrotum Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


name: Exocrine Pancreatic Cancer Pathologic Primary Tumor TNM Finding v6

description: A pathologic finding about one or more characteristics of exocrine pancreatic cancer, following the rules of the TNM AJCC v6 classification system as they pertain to staging of the primary tumor.


name: Grade 5 Leukemia Secondary To Oncology Chemotherapy, CTCAE

description: Death


name: Unspecified Diabetes Mellitus in Childbirth

description: Evidence of unspecified diabetes mellitus in childbirth.


name: Grade 3 Alkaline Phosphatase Increased, CTCAE

description: >5.0-20.0 x ULN if baseline was normal; >5.0-20.0 x baseline if baseline was abnormal


Grade 2 Euphoria, CTCAE

description: Moderate mood elevation


name: Melanoma in situ of ear and external auricular canal

description: Evidence of melanoma in situ of ear and external auricular canal.


Nutritional Calcium Deficient Rickets

description: Nutritional rickets due to dietary deficiency of calcium.


name: Grade 3 Lung Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


Cervical Cancer pT1a1 TNM Finding v8

description: Invasive cervical carcinoma with measured stromal invasion of 3.0 mm or less in depth and 7.0 mm or less in horizontal spread. (from AJCC 8th Ed.)


name: oligoarticular juvenile idiopathic arthritis of shoulder

description: Evidence of pauciarticular juvenile rheumatoid arthritis in an unspecified shoulder.


name: Hypogonadotropic Hypogonadism with Adrenal Hypoplasia Congenita

description: Hypogonadotropic hypogonadism with congenital adrenal hypoplasia associated with mutation(s) in the NR0B1 gene (on the X chromosome).


name: PSA Doubling Time Greater than or Equal to 4 Months

description: An indication that the number of months that a subject's blood concentration of prostate specific antigen took at least 4 months to double.


name: Sedative, Hypnotic or Anxiolytic Abuse with Mood Disorder

description: Evidence of sedative, hypnotic or anxiolytic abuse with mood disorder.


Lung Cancer pMX TNM Finding v6

description: Lung cancer in which distant metastasis cannot be assessed. (from AJCC 6th Ed.)


name: Testicular Cancer Clinical Regional Lymph Nodes TNM Finding v7

description: A clinical finding about one or more characteristics of testicular cancer, following the rules of the TNM AJCC v7 classification system as they pertain to staging of regional lymph nodes.  (from AJCC 7th Ed.)


name: Pleura Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


Adult Atypical Meningioma

description: An atypical meningioma that occurs during adulthood.


Grade 5 Hyperkalemia, CTCAE

description: Death


Grade 3 Hypokalemia, CTCAE

description: <3.0-2.5 mmol/L; hospitalization indicated


Grade 4 Lung Infection, CTCAE

description: Life-threatening consequences; urgent intervention indicated


IgM Monoclonal Gammopathy

description: An abnormal laboratory test result indicating the presence of IgM monoclonal immunoglobulin in the blood or urine.


name: Stage IIIB Esophageal Adenocarcinoma AJCC v7

description: Stage IIIB includes: T3, N2, M0, Any G. T3: Tumor invades adventitia. N2: Metastasis in 3-6 regional lymph nodes.  M0: No distant metastasis.  (AJCC 7th ed.)


name: Grade 1 Pancreatic Duct Intra-Operative Injury, CTCAE


name: Grade 4 Small Bowel Mucositis or Stomatitis by Clinical Examination Classification, CTCAE


name: Radiating Chest Pain Along Right Upper Sternal Border

description: The location of the radiating chest pain is along the right upper sternal border.


Death Related to Adverse Event

description: The termination of life associated with an adverse event.


Obstructed Megaureter

description: A megaureter in which there is obstruction to the flow of urine at the ureterovesical junction.


Grade 3 Uterine Fistula, CTCAE

description: Invasive intervention indicated


name: Secondary Graft Failure After Hematopoietic Cell Transplantation

description: Loss of donor hematopoietic cells following initial engraftment.


name: Unspecified Dementia without Behavioral Disturbance

description: Evidence of unspecified dementia without behavioral disturbance.


name: Other Paralytic Syndrome following Other Non-Traumatic Intracranial Hemorrhage Affecting Unspecified Side

description: Evidence of other paralytic syndrome following other non-traumatic intracranial hemorrhage affecting unspecified side not specified elsewhere.


name: Dysarthria following Cerebral Infarction

description: Evidence of dysarthria following cerebral infarction.


Hindgut Neuroendocrine Tumor G2

description: A neuroendocrine tumor grade 2 that arises from the sigmoid colon, descending colon, or rectum.


name: Grade 4 Cranial Nerve IX Sensory Intra-Operative Injury, CTCAE


Grade 4 Colonic Ulcer, CTCAE

description: Life-threatening consequences; urgent operative intervention indicated


name: Thoracic Procedure Postoperative Complication

description: Any disorder occurring postoperatively as a consequence of a thoracic procedure.


atheroembolism of right lower extremity

description: Evidence of atheroembolism of right lower extremity.


Abdominal Distension, CTCAE

description: A disorder characterized by swelling of the abdomen.


name: Exocrine Pancreatic Cancer pT3 TNM Finding v6

description: Exocrine pancreatic cancer extending beyond the pancreas, but without involvement of the celiac axis or superior mesenteric artery. (from AJCC 6th Ed.)


name: Locally Advanced Large Cell Neuroendocrine Carcinoma

description: A large cell neuroendocrine carcinoma that has spread from its original site of growth to nearby tissues or lymph nodes.


Hypoechoic Focus

description: A radiologic finding describing a region in an image with a signal lower than that of the surrounding regions.


name: Grade 1 Lingual Nerve Intra-Operative Injury, CTCAE


Bone Marrow Hypocellular, CTCAE

description: A disorder characterized by the inability of the bone marrow to produce hematopoietic elements.


Eyelid Carcinoma pT2b TNM Finding v8

description: Eyelid carcinoma with tumor measuring more than 10 mm but 20 mm or less in greatest dimension with invasion of the tarsal plate or eyelid margin. (from AJCC 8th Ed.)


Hypoproteinemia

description: A laboratory test result indicating abnormally low levels of total protein in the serum.


Infusion Related Adverse Event

description: An adverse event that can be related to an infusion.


CTCAE v4 Grade 1

description: An adverse event that is asymptomatic; or involves mild or minor symptoms; or is of marginal clinical relevance; or consists of clinical or diagnostic observations alone; or for which intervention is not indicated; or for which only non-prescription intervention is indicated.


name: Spinal Cord Infection with Unknown Absolute Neutrophil Count, CTCAE


name: Stage II Centroblastic Follicular Lymphoma

description: Ann Arbor Classification: Stage II: Involvement of two or more lymph node regions on the same side of the diaphragm (II); or localized involvement of a single extralymphatic organ or site in association with regional lymph node involvement with or without involvement of other lymph node regions on the same side of the diaphragm (IIE).


Grade 5 Suicide Attempt, CTCAE

description: Death


Extrahepatic bile duct cancer stage II

description: Stage II includes: IIA: (T3, N0, M0); IIB: (T1, N1, M0); (T2, N1, M0); (T3, N1, M0).  T3: Tumor invades the liver, gallbladder, pancreas, and/or unilateral branches or the portal vein (right or left) or hepatic artery (right or left).  N1: Regional lymph node metastasis.  M0: No distant metastasis. (AJCC 6th ed.)


Eyelid Carcinoma pN2b TNM Finding v8

description: Eyelid carcinoma with metastasis in a single ipsilateral regional lymph node, measuring more than 3 cm in greatest dimension, or in bilateral or contralateral lymph nodes documented based on microscopic findings on lymph node biopsy. (from AJCC 8th Ed.)


Grade 2 Lymph Node Pain, CTCAE

description: Moderate pain; limiting instrumental ADL


Breast hyperplasia

description: A general term that refers to hyperplastic proliferations of the epithelial cells in the breast parenchyma.  Examples include atypical ductal hyperplasia, usual ductal hyperplasia, columnar cell hyperplasia, and atypical lobular hyperplasia.


Testicular Cystic Trophoblastic Tumor

description: A rare trophoblastic neoplasm that arises in metastatic sites of testicular mixed germ cell tumors following chemotherapy, or is part of treated or untreated testicular mixed germ cell tumors, or is secondary to either chemotherapy-induced or spontaneous regression of testicular choriocarcinoma. It is characterized by the presence of cysts lined by squamoid trophoblastic cells. The cysts are often compressed surrounded by other germ cell components.


name: Follicular Lymphoma Grade I, Extranodal and Solid Organ Sites

description: Evidence of follicular lymphoma grade I in the extranodal and solid organ sites.


name: Rheumatic tricuspid stenosis and insufficiency

description: Evidence of rheumatic tricuspid stenosis and insufficiency.


name: Grade 2 Rectum Mucositis or Stomatitis by Functional or Symptomatic Classification, CTCAE


Grade 5 Neonatal Sinus Bradycardia, AE

description: A sinus bradycardia adverse event in a newborn which results in death.


Blood Gonadotrophin Abnormal, CTCAE

description: A finding based on laboratory test results that indicate abnormal levels of gonadotrophin hormone in a blood specimen.


Injury To Inferior Vena Cava, CTCAE

description: A finding of damage to the inferior vena cava.


Genitourinary Signs and Symptoms

description: Patient complaints (symptoms), physical or laboratory findings (signs) related to the genitourinary system.


name: Cranial Nerve III Intra-Operative Injury, CTCAE


Annular Lesion

description: A ring-shaped skin finding with clear central area.


Grade 3 Optic Nerve Disorder, CTCAE

description: Marked decrease in visual acuity (best corrected visual acuity worse than 20/40 or more than 3 lines of decreased vision from known baseline, up to 20/200)


Grade 4 Cardiac Arrest, CTCAE

description: Life-threatening consequences; urgent intervention indicated


name: Grade 2 Small Bowel Infection NOS Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


name: Burkitt's lymphoma of intrapelvic lymph nodes

description: Evidence of Burkitt lymphoma in the intrapelvic lymph nodes.


name: Grade 4 Vagina Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


name: Grade 5 Personality and Behavioral Change, CTCAE


name: Grade 1 Colon Intra-Operative Injury, CTCAE


name: Grade 2 Urinary Tract Infection NOS with Unknown Absolute Neutrophil Count, CTCAE


Nickel Metabolic Disorder

description: A storage disorder that results from impaired metabolism of nickel.


name: Recurrent Polymorphous Low Grade Neuroepithelial Tumor of the Young

description: The reemergence of polymorphous low-grade neuroepithelial tumor of the young after a period of remission.


name: Malignant Neoplasm of Short Bones of Unspecified Upper Limb

description: Evidence of a malignant neoplasm of the short bones of unspecified upper limb.


name: DNA Methylation Profiling Status Unknown

description: A finding indicating that there is no information regarding molecular analysis for DNA methylation profiling in a tumor sample.


Grade 3 Hypernatremia, CTCAE

description: >155-160 mmol/L; hospitalization indicated


PSA Level Greater than 0.5

description: A blood concentration of prostate specific antigen greater than 0.5 ng/mL.


Grade 1 Alopecia, CTCAE

description: Hair loss of <50% of normal for that individual that is not obvious from a distance but only on close inspection; a different hair style may be required to cover the hair loss but it does not require a wig or hair piece to camouflage


name: Atherosclerosis of Native Arteries of Right Leg with Ulceration of Calf

description: Evidence of atherosclerosis of native arteries of right leg with ulceration of calf.


Passive Smoke Exposure

description: Exposure to tobacco smoke products among individuals who do not smoke. This can result from sharing space with a smoker or from placental transfer from mother to fetus.


name: Rectum Mucositis or Stomatitis by Clinical Examination Classification, CTCAE


name: Nose Infection with Unknown Absolute Neutrophil Count, CTCAE


Grade 2 Rectal Ulcer, CTCAE

description: Symptomatic; altered GI function (e.g., altered dietary habits, vomiting, diarrhea)


Malignant neoplasm of bladder recurrent

description: The reemergence of a malignant bladder neoplasm after a period of remission.


Ph -/BCR-ABL-

description: Philadelphia chromosome abnormality; t(9;22)(q34;q11) was not found; bcr/abl gene rearrangement was not found.


name: Grade 5 Esophagus Infection with Unknown Absolute Neutrophil Count, CTCAE


Gastrointestinal carcinoma in situ

description: An intraepithelial carcinoma arising from any part of the digestive system without evidence of invasion.


HER2/Neu Negative

description: The absence of detectable HER2/Neu in a tissue sample.


name: Colorectal Cancer pT0 TNM Finding v6 and v7

description: Colorectal cancer with no evidence of primary tumor. (from AJCC 6th and 7th Eds.)