phosphatidylglycerol 18:1/18:1

A phosphatidylglycerol 36:1 in which both acyl groups contains 18 carbons and 1 double bond.


triacylglycerol 50:7

A triglyceride in which the three acyl groups contain a total of 50 carbons and 7 double bonds.


lysophosphatidylserine 19:1

A lysophosphatidylserine in which the remaining acyl group (position not specified) contains 19 carbons and 1 double bond.


A 1-alkyl-2-acetyl-3-acyl-sn-glycerol in which the alkyl and acyl groups are specified as palmityl and capryl.


diradylglycerol

Any lipid that is glycerol bearing two substituent groups - either acyl, alkyl, or alk-1-enyl - at any two of the three possible positions.


phosphatidylserine (18:1/20:4)

A phosphatidylserine 38:5 in which the acyl group at C-1 contains 18 carbons and 1 double bond while that at C-2 contains 20 carbons and 4 double bonds.


lysophosphatidylserine 18:4

A lysophosphatidylserine in which the remaining acyl group (position not specified) contains 18 carbons and 4 double bonds.


An N-acylphosphatidylethanolamine in which the N-acyl group is specified as stearoyl (octadecanoyl) while the phosphatidyl acyl groups are both specified as oleoyl (9Z-octadecenoyl).


A triacyl-sn-glycerol in which the which the acyl groups at positions 1, 2 and 3 are specified as hexadecanoyl, octadecanoyl and (9Z)-octadecenoyl respectively.


A 2-acyl-sn-glycerol 3-phosphate in which the phosphatidyl acyl group is specified as arachidonoyl.


phosphatidylethanolamine (16:0/16:1)

1,2-diacyl-sn-glycero-3-phosphoethanolamine  in which the acyl group at C-1 contains 16 carbons and no double bonds while that at C-2 contains 16 carbons and 1 double bond.


A 1-acyl-sn-glycerol that is the S-enantiomer of  2,3-dihydroxypropyl dodecanoate (glyceryl monolaurate).


triacylglycerol 56:3

A triglyceride in which the three acyl groups contain a total of 56 carbons and 3 double bonds.


A triacylglycerol 60:10 in which the acyl groups at positions 1, 2 and 3 are specified as octadecanoyl, icosatetraenoyl and docosahexaenoyl respectively.


triacylglycerol 53:2

A triglyceride in which the three acyl groups contain a total of 53 carbons and 2 double bonds.


phosphatidylserine 36:2

A 3-sn-phosphatidyl-L-serine in which the two acyl groups contain a total of 36 carbon atoms and 2 double bonds.


An N-acyl-sn-glycero-3-phosphoethanolamine in which the N-acyl group is specified as arachidonoyl (5Z,8Z,11Z,14Z-icosatetraenoyl).


monoacyl-sn-glycerol 3-phosphate

An sn-glycero-3-phosphate compound having a single unspecified acyl group at either position 1 or position 2.


A monoacylglycerol 20:5 in which the acyl group specified at position 2 is (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoyl.


phosphatidylserine (18:0/22:5)

A phosphatidylserine 40:5 in which the acyl group at C-1 contains 18 carbons and no double bonds while that at C-2 contains 22 carbons and 5 double bonds.


A triglyceride formed by acylation of the three hydroxy groups of glycerol with palmitoleic acid.


name: 15-methyl-9-hexadecenoic acid 2,3-dihydroxypropyl ester


A 1-acyl-sn-glycero-3-phosphoethanolamine in which the acyl group is specified as icosanoyl.


phosphatidylethanolamine 36:3

A phosphatidylethanolamine in which the acyl groups at C-1 and C-2 contain 36 carbons in total with 3 double bonds.


cardiolipin (20:2/16:1/18:1/18:3)

A cardiolipin in which the four acyl groups are specified as icosadienoyl, hexadecenoyl, octadecenoyl and octadecatrienoyl.


phosphatidylethanolamine 39:1

A phosphatidylethanolamine in which the two acyl groups contain a total of 39 carbons and 1 double bond.


A glycerolipid where one of the acyl groups is specified as (11Z,14Z,17Z)-icosatrienoyl.


phosphatidylethanolamine 33:2

A phosphatidylethanolamine in which the two acyl groups contain a total of 33 carbons and 2 double bonds.


A 1-(alk-1-enyl)-2-acyl-sn-glycero-3-phosphoethanolamine zwitterion in which the alkenyl and acyl groups are specified as (1Z)-hexadecenyl and linoleoyl respectively.


monooctanoylglycerol

A monoglyceride in which the acyl group is octanoyl with the position of acylation unspecified.


A 1,2-diacyl-sn-glycerol 3-phosphate in which the acyl substituents at positions 1 and 2 are specified as icosanoyl (arachidoyl) and oleoyl respectively.


A 2-monoglyceride in which the acyl group is specified as (9E)-9-octadecenoyl.


A glycerolipid where one of the acyl groups is specified as gamma-linolenoyl


phosphatidylserine 42:2

A 3-sn-phosphatidyl-L-serine in which the two acyl groups contain a total of 42 carbon atoms and 2 double bonds.


phosphatidylinositol mannoside

A glycosylphosphatidylinositol having mannose as the glycosyl moiety.


A 1-(Z-alk-1-enyl)-sn-glycero-3-phosphoethanolamine zwitterion in which the Z-alk-1-enyl group contains 18 carbons and has 1 additional double bond


A 1,2-diacyl-sn-glycero-3-phosphoethanolamine in which the 1- and 2-acyl groups are specified as hexadecanoyl (palmitoyl) and octadecanoyl (stearoyl) respectively.


phosphatidylethanolamine (17:0/22:6)

A phosphatidylethanolamine 39:6 in which the acyl group at C-1 contains 17 carbons and no double bonds while that at C-2 contains 22 carbons and 6 double bonds.


triacylglycerol 51:1

A triglyceride in which the three acyl groups contain a total of 51 carbons and 1 double bond.


monoacylglycerol 16:5

A monoacylglycerol in which the acyl group contains a total of 16 carbons and 5 double bonds.


phosphatidylserine (20:4/20:4)

A phosphatidyl-L-serine in which both acyl groups have 20 carbons and 4 double bonds.


triacylglycerol 50:8

A triglyceride in which the three acyl groups contain a total of 50 carbons and 8 double bonds.


A triacylglycerol 58:9 in which the acyl groups at positions 1, 2 and 3 are specified as octadecenoyl, octadecadienoyl and docosahexaenoyl respectively.


triacylglycerol 60:11

A triglyceride in which the three acyl groups contain a total of 60 carbons and 11 double bonds.


An N-acylphosphatidylethanolamine in which the N-acyl group is specified as butyryl while the phosphatidyl acyl groups at position 1 and 2 are specified as palmitoyl (hexadecanoyl) and linoleoyl (9Z,12Z-octadecadienoyl) respectively.


A 1,2-diacyl-sn-glycero-3-phospho-N-methylethanolamine in which the phosphatidyl acyl groups are both specified as oleoyl (9Z-octadecenoyl); major species at pH 7.3.


An N-acyllysophosphatidylethanolamine in which both the N- and O-acyl group are specified as oleoyl (9Z-octadecenoyl).


An N-acyllysophosphatidylethanolamine in which the N-acyl group is specified as arachidonoyl while the phosphatidyl acyl group is specified as oleoyl.


A 1-acyl-2-arachidonoyl-sn-glycero-3-phosphate in which the 1-acyl group is also arachidonoyl.


A triacylglycerol 38:0 in which the acyl groups at positions 1, 2 and 3 are specified as octanoyl, tetradecanoyl and hexadecanoyl respectively.


lysophosphatidylserine 14:0

A lysophosphatidylserine in which the remaining acyl group (position not specified) contains 14 carbons and 0 double bonds.


lysophosphatidylinositol 18:2

A lysophosphatidyl-1D-myo-inositol in which the remaining acyl group (position not specified) contains 18 carbons and 2 double bonds.


A 1,2-diacyl-sn-glycero-3-phosphoethanolamine in which the acyl groups at positions 1 and 2 are specified as (11Z,14Z)-icosadienoyl and (4Z,7Z,10Z,13Z,16Z)-docosapentaenoyl respectively.


A 1-phosphatidyl-1D-myo-inositol in which the phosphatidyl acyl groups at positions 1 and 2 are specified as (8Z,11Z,14Z,17Z)-icosatetraenoyl and (11Z)-octadecenoyl respectively.


A phosphatidylglycerol 36:3 in which one acyl group has 18 carbons and 1 double bond while the other has 18 carbons and 2 double bonds (position not specified).


A triacylglycerol 62:10 in which the acyl groups at positions 1, 2 and 3 are specified as octadecanoyl, docosatetraenoyl and docosahexaenoyl respectively.


A phosphatidyl-N-methylethanolamine (1,2-diacylglycero-3-phospho-N-methylethanolamine) in which the stereochemistry of the glycerol moiety is specified as sn.


A phosphatidylinositol 38:4 in which one acyl group has 18 carbons and is fully saturated while the other has 20 carbons and 4 double bonds (position not specified).


A 1,2-diacyl-sn-glycero-3-phosphoethanolamine in which the 1- and 2-acyl groups are specified as oleoyl and arachidonoyl respectively.


A 1-acyl-sn-glycero-3-phosphoethanolamine in which the acyl group is specified as 4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl.


glycosylmonoacylglycerol

Any glycosylmonoglyceride in which the glycosyl moiety is attached to one of the primary hydroxy groups and the acyl group position is not defined.


A 2-monoglyceride where the acyl group is tetradecanoyl (myristoyl).


1-(alk-1-enyl)-sn-glycero-3-phosphoethanolamine in which the alk-1-enyl group is specified as (E)-hexadec-1-enyl.


A 1-monoglyceride in which the acyl group is specified as (9E)-octadecenoyl.


A 1-alkyl-2-acylglycerol having acetyl as the acyl substituent.


phosphatidylserine (18:1/22:6)

A phosphatidylserine 40:7 in which the acyl group at C-1 contains 18 carbons and 1 double bond while that at C-2 contains 22 carbons and 6 double bonds.


lysophosphatidic acid 0:0/18:2(9Z,12Z)

A 2-acyl-sn-glycerol 3-phosphate having (9Z,12Z)-octadeca-9,12-dienoyl as the 2-O-acyl group.


lysophosphatidylserine 20:1

A lysophosphatidylserine in which the remaining acyl group (position not specified) contains 20 carbons and 1 double bond.


triacylglycerol 55:6

A triglyceride in which the three acyl groups contain a total of 55 carbons and 6 double bonds.


lysophosphatidylethanolamine 20:5

A lysophosphatidylethanolamine in which the acyl group (position not specified) contains 20 carbons and 5 double bonds.


A triglyceride formed by acylation of the three hydroxy groups of glycerol with linolenic acid.


A triacylglycerol 52:3 in which the acyl groups at positions 1, 2 and 3 are specified as palmitoyl, linoleoyl and oleoyl respectively.


distearoyl phosphatidylglycerol

A phosphatidylglycerol in which the phosphatidyl acyl groups are both stearoyl.


triacylglycerol 58:4

A triglyceride in which the three acyl groups contain a total of 58 carbons and 4 double bonds.


A 1-(alk-1-enyl)-2-arachidonoyl-sn-glycero-3-phosphoethanolamine zwitterion in which the alk-1-enyl group has Z geochemistry.


lysophosphatidylserine 20:2

A lysophosphatidylserine in which the remaining acyl group (position not specified) contains 20 carbons and 1 double bonds.


lysophosphatidylethanolamine 18:2

A lysophosphatidylethanolamine in which the acyl group (position not specified) contains 18 carbons and 2 double bonds.


A 2-acyl-sn-glycero-3-phosphoserine in which the 2-acyl group is specified as arachidonoyl.


A 1,2-diacyl-sn-glycerol 3-phosphate in which the acyl group at position 1 is unspecified while that at position 2 is specified as oleoyl


phosphatidylinositol (16:0/18:1)

A phosphatidylinositol 34:1 in which the acyl group at position 1 contains 16 carbons and no double bonds while that at position 2 contains 18 carbons and 1 double bond.


A phosphatidylglycerol that is the 3'-O-L-lysyl of any 1,2-diacyl-sn-glycero-3-phospho-1'-sn-glycerol.


A 3-(3-sn-phosphatidyl)-sn-glycerol 1-phosphate in which both phosphatidyl acyl groups are specified as hexadecanoyl (palmitoyl).


triacylglycerol 55:10

A triglyceride in which the three acyl groups contain a total of 55 carbons and 10 double bonds.


lysophosphatidylserine 20:5

A lysophosphatidylserine in which the remaining acyl group (position not specified) contains 20 carbons and 5 double bonds.


A triacylglycerol 58:4 in which the acyl groups at positions 1, 2 and 3 are specified as octadecanoyl, icosanoyl and icosatetraenoyl respectively.


A 1-(Z)-alk-1-enyl-2-acyl-sn-glycero-3-phosphoethanolamine zwitterion in which the alkenyl and acyl groups are specified as (1Z)-octadecenyl and linoleoyl respectively.


triacylglycerol 42:4

A triglyceride in which the three acyl groups contain a total of 42 carbons and 4 double bonds.


A triacylglycerol 44:2 in which the acyl groups at positions 1, 2 are specified as tetradecenoyl while that at position 3 is specified as hexadecanoyl.


glycerophosphoinositol trisphosphate

Any glycerophosphoinositol bearing three additional phospho substituents on the inositol ring.


phosphatidylinositol 3-phosphate

A phosphatidylinositol monophosphate carrying the phosphate group at the 3-position.


A 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) in which the acyl group at position 1 is unspecified while that at position 2 is specified as palmitoyl.


A 2-monoglyceride in which the acyl group is specified as (9E,12E,15E)-octadecatrienoyl.


A glycerolipid where one of the acyl groups is specified as (7Z,10Z,13Z,16Z)-docosatetraenoyl.


A phosphatidylinositol 4-phosphate having 1D-myo-configuration.


triacylglycerol 52:3

A triglyceride in which the three acyl groups contain a total of 52 carbons and 3 double bonds.


CDP-acylglycerol

A CDP-glycerol compound having an acyl substituent on its primary hydroxyl group.


A 1-alkyl-2-acetyl-3-acyl-sn-glycerol in which the alkyl and acyl groups are specified as palmityl and capryloyl.


A 1-monoglyceride that has alpha-linolenoyl as the acyl group.


phosphatidylglycerol (18:3/16:0)

A phosphatidylglycerol 34:3 in which the 1- and 2-acyl groups are specified as octadecatrienoyl and hexadecanoyl respectively.


A phosphatidylethanolamine 35:2 in which the acyl group at C-1 contains 18 carbons and 1 double bond while that at C-2 contains 17 carbons and 1 double bond.


triacylglycerol 55:5

A triglyceride in which the three acyl groups contain a total of 55 carbons and 5 double bonds.


phosphatidylglycerol 12:0

A 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) in which the acyl groups at C-1 and C-2 contain 12 carbons in total with no double bonds.


triacylglycerol 55:2

A triglyceride in which the three acyl groups contain a total of 55 carbons and 2 double bonds.


LYSOPHOSPHATIDIC ACID

A 1-acyl-sn-glycerol 3-phosphate having oleoyl as the 1-O-acyl group.


A glycerolipid where one of the acyl groups is specified as (4Z,7Z,10Z,13Z,16Z)-docosapentaenoyl.


trilinoleoyl 2-monolysocardiolipin

A 2-monolysocardiolipin in which all three phosphatidyl acyl groups are specified as linoleoyl.


name: Hepatitis Virus-Related Hepatocellular Carcinoma

category: biolink:Disease biolink:DiseaseOrPhenotypicFeature biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing

description: A hepatocellular carcinoma that develops following hepatitis virus exposure and injury of the liver parenchyma.


Stage IIIA Adult Liver Cancer AJCC v7

description: For hepatocellular carcinoma: Stage IIIA includes: T3a, N0, M0. T3a: Multiple tumors more than 5 cm. N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 7th ed.)


name: Epithelioid hemangioendothelioma of liver

description: A low-grade malignant blood vessel neoplasm that arises from the liver.  It is characterized by the presence of epithelioid endothelial cells.  The neoplastic cells are arranged in cords and nests, which are embedded in a myxoid to hyalinized stroma.  Patients may be asymptomatic or present with an abdominal mass, ascites, and jaundice.


name: Stage I Intrahepatic Bile Duct Cancer AJCC v8

description: Stage I includes: IA (T1a, N0, M0); IB (T1b, N0, M0). T1a: Solitary tumor equal to or less than 5 cm without vascular invasion.  T1b: Solitary tumor larger than 5 cm without vascular invasion. N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 8th ed.)


Unresectable Fibrolamellar Carcinoma

description: A fibrolamellar carcinoma that is not amenable to surgical resection.


name: Hepatoblastoma with Pure Fetal Epithelial Differentiation

description: A hepatoblastoma composed of small cells resembling the fetal hepatocytes, forming thin trabeculae.


name: Recurrent Adult Hepatocellular Carcinoma

description: A hepatocellular carcinoma that occurs during adulthood and has recurred after a period of remission.


name: Locally Advanced Hepatocellular Carcinoma

description: Hepatocellular carcinoma that has spread to nearby tissues or lymph nodes.


Hepatoblastoma recurrent

description: The reemergence of hepatoblastoma after a period of remission.


name: Stage IV Childhood Hepatocellular Carcinoma AJCC v7

description: Stage IV includes: IVA: (Any T, N1, M0); IVB: (Any T, Any N, M1). N1: Regional lymph node metastasis. M0: No distant metastasis.  M1: Distant metastasis. (AJCC 7th ed.)


BCLC Stage 0 Hepatocellular Carcinoma

description: Very early hepatocellular carcinoma. Patients are optimal candidates for resection. (HPB (Oxford) 2005; 7(1):35-41)


BCLC Stage D Hepatocellular Carcinoma

description: End-stage hepatocellular carcinoma.  Patients will receive symptomatic treatment. (HPB (Oxford) 2005; 7(1):35-41)


Localized PRETEX III Hepatoblastoma

description: PRETEX III hepatoblastoma confined to the liver including regional lymph nodes. (Childhood cancer staging for population registries according to the Toronto Childhood Cancer Stage Guidelines - Version 2. Cancer Council Queensland and Cancer Australia: Brisbane, Australia; 2021.)


Adult Liver Carcinoma

description: A hepatocellular carcinoma or intrahepatic cholangiocarcinoma that occurs during adulthood.


Liver Synovial Sarcoma

description: A synovial sarcoma that affects the liver.


Stage IV Liver Cancer

description: Stage IV carcinoma of the liver according to the American Joint Committee on Cancer, 6th, 7th, and 8th editions.


Metastatic Fibrolamellar Carcinoma

description: A fibrolamellar carcinoma that has spread from the liver to another anatomic site.


name: Stage III Hepatocellular Carcinoma AJCC v7

description: Stage III includes: IIIA: (T3a, N0, M0); IIIB: (T3b, N0, M0); IIIC: (T4, N0, M0). T3a: Multiple tumors more than 5 cm. T3b: Single tumor or multiple tumors of any size involving a major branch of the portal vein or hepatic vein.  T4: Tumors(s) with direct invasion of adjacent organs other than the gallbladder or with perforation of visceral peritoneum. N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 7th ed.)


name: Stage IVA Hepatocellular Carcinoma AJCC v7

description: Stage IVA includes: Any T, N1, M0.  N1: Regional lymph node metastasis. M0: No distant metastasis.  (AJCC 7th ed.)


PRETEXT IV Hepatoblastoma

description: An internationally developed presurgical anatomic staging system using imaging techniques: Tumor involves all 4 quadrants; there is no quadrant free of tumor. (from PDQ 2004)


Non-Resectable Malignant Liver Neoplasm

description: A malignant liver neoplasm that is not amenable to surgical resection.


Metastatic liver carcinoma

description: A carcinoma that arises from the liver and has spread to another anatomic site.


name: Adult Pleomorphic Hepatocellular Carcinoma

description: A pleomorphic hepatocellular carcinoma that occurs during adulthood.


name: Childhood Hepatoblastoma by Toronto Guidelines v2 Stage, Tier 2

description: A term that refers to the staging of childhood hepatoblastoma according to the tier 2 Toronto childhood cancer staging guidelines v2. It includes localized tumors, metastatic tumors, and the PRETEXT system. (Childhood cancer staging for population registries according to the Toronto Childhood Cancer Stage Guidelines - Version 2. Cancer Council Queensland and Cancer Australia: Brisbane, Australia; 2021.)


name: Stage IV Hepatocellular Carcinoma AJCC v7


name: BCLC Stage C Adult Hepatocellular Carcinoma

description: Advanced hepatocellular carcinoma.  Patients may receive new agents in the setting of randomized controlled trials. (HPB (Oxford) 2005; 7(1):35-41)


name: Stage IV Hepatocellular Carcinoma AJCC v6

description: Stage IV includes (Any T, Any N, M1).  M1: Distant metastasis. (AJCC 6th ed.)


Extrarenal Rhabdoid Tumor of the Liver

description: A rare, aggressive primary malignant tumor of the liver that occurs in childhood.  It is characterized by the presence of a diffuse infiltrate of undifferentiated cells with rhabdoid features.


Adult Liver Embryonal Sarcoma

description: An embryonal sarcoma of the liver that occurs during adulthood.


Stage II Liver Cancer

description: Stage II carcinoma of the liver according to the American Joint Committee on Cancer, 6th, 7th, and 8th editions.


Postsurgical Stage III Hepatoblastoma

description: No distant metastases, tumor unresectable or resected with gross residual tumor, or positive lymph nodes. (from PDQ 2004)


PRETEXT III Hepatoblastoma

description: An internationally developed presurgical anatomic staging system using imaging techniques: Tumor involves 3 adjoining quadrants or 2 nonadjoining quadrants; 1 quadrant or 2 nonadjoining quadrants are free of tumor. (from PDQ 2004)


Refractory Hepatoblastoma

description: Hepatoblastoma that does not respond to treatment.


Uveal Melanoma Metastatic in the Liver

description: A melanoma that originates from melanocytes of the uveal tract and has spread to the liver.


name: Stage II Hepatocellular Carcinoma AJCC v8

description: Stage II includes: T2, N0, M0. T2: Solitary tumor larger than 2 cm with vascular invasion, or multiple tumors, none larger than 5 cm. N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 8th ed.)


name: Liver Small Cell Neuroendocrine Carcinoma

description: An aggressive, high-grade, and poorly differentiated carcinoma with neuroendocrine differentiation that arises from the liver. It is characterized by the presence of malignant small cells.


name: Stage IV Intrahepatic Bile Duct Cancer AJCC v8

description: Stage IV includes: Any T, Any N, M1. M1: Distant metastasis. (AJCC 8th ed.)


name: Stage IIIA Hepatocellular Carcinoma AJCC v7

description: Stage IIIA includes: T3a, N0, M0.  T3a: Multiple tumors more than 5 cm. N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 7th ed.)


Stage III Liver Cancer

description: Stage III carcinoma of the liver according to the American Joint Committee on Cancer, 6th, 7th, and 8th editions.


name: Epithelial Hepatoblastoma with Pleomorphic Pattern

description: Epithelial hepatoblastoma characterized by the presence of fetal or embryonal cells showing nuclear pleomorphism. Malignant giant cells may be present.


Stage IIIC Adult Liver Cancer AJCC v7

description: For hepatocellular carcinoma: Stage IIIC includes: T4, N0, M0.  T4: Tumors(s) with direct invasion of adjacent organs other than the gallbladder or with perforation of visceral peritoneum. N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 7th ed.)


name: Stage I Hepatocellular Carcinoma AJCC v6 and v7

description: Stage I includes: T1, N0, M0.  T1: Solitary tumor without vascular invasion.  N0: No regional lymph node metastasis.  M0: No distant metastasis. (AJCC 6th and 7th eds.)


Colon Carcinoma Metastatic in the Liver

description: A carcinoma that originates from the colonic wall and has spread to the liver.


name: Stage III Hepatocellular Carcinoma AJCC v8

description: Stage III includes: IIIA: (T3, N0, M0); IIIB: (T4, N0, M0). T3: Multiple tumors, at least one of which is larger than 5 cm. T4: Single tumor or multiple tumors of any size involving a major branch of the portal vein or hepatic vein, or tumor(s) with direct invasion of adjacent organs other than the gallbladder or with perforation of visceral peritoneum. N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 8th ed.)


Non-Teratoid Hepatoblastoma

description: A mixed epithelial and mesenchymal hepatoblastoma characterized by the absence of heterologous elements, muscle, cartilage or osteoid.


name: Stage IIIA Intrahepatic Bile Duct Cancer AJCC v8

description: Stage IIIA includes: T3, N0, M0. T3: Tumor perforating the visceral peritoneum. N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 8th ed.)


name: Liver Mixed Adenoneuroendocrine Carcinoma

description: A carcinoma that arises from the liver and is characterized by the presence of a malignant glandular epithelial component and a malignant neuroendocrine component.  At least 30 percent of either component should be present for the diagnosis to be made.


name: Moderately Differentiated Hepatocellular Carcinoma

description: A hepatocellular carcinoma characterized by the presence of malignant cells with abundant eosinophilic cytoplasm forming trabecular and pseudoglandular patterns.  It is usually associated with tumors that are larger than 3 cm in diameter.


name: Hepatocellular carcinoma, spindle cell variant

description: A morphologic variant of hepatocellular carcinoma characterized by the presence of malignant spindle cells or atypical giant cells.


carcinosarcoma of liver

description: An aggressive carcinoma with a sarcomatous component that arises from the liver.  The sarcomatous component is clonally related to the more differentiated, carcinomatous component.  The prognosis is usually poor.


Hepatic cancer stage IVA

description: Stage IVA carcinoma of the liver according to the American Joint Committee on Cancer, 7th and 8th editions.


name: Stage II Intrahepatic Bile Duct Cancer AJCC v8

description: Stage II includes: T2, N0, M0. T2: Solitary tumor with intrahepatic vascular invasion, or multiple tumors, with or without vascular invasion. N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 8th ed.)


name: Hepatocellular Malignant Neoplasm, Not Otherwise Specified

description: A rare childhood malignant liver neoplasm with overlapping features of hepatoblastoma and hepatocellular carcinoma.


name: Stage I Childhood Hepatocellular Carcinoma AJCC v6 and v7


Locally Advanced Liver Carcinoma

description: Liver carcinoma that has spread from its original site of growth to nearby tissues or lymph nodes.


Teratoid Hepatoblastoma

description: A mixed epithelial and mesenchymal hepatoblastoma characterized by the presence of heterologous elements. The latter include neuroectoderm, endoderm, or melanin-holding cells. Muscle, cartilage and osteoid may or may not be present.


BCLC Stage B Hepatocellular Carcinoma

description: Intermediate hepatocellular carcinoma.  Patients may benefit from chemoembolization. (HPB (Oxford) 2005; 7(1):35-41)


Kaposi's sarcoma of liver

description: A Kaposi sarcoma that arises from the liver.


name: Stage IA Intrahepatic Bile Duct Cancer AJCC v8

description: Stage IA includes: T1a, N0, M0. T1a: Solitary tumor equal to or less than 5 cm without vascular invasion.  N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 8th ed.)


description: Hepatocellular carcinoma characterized by the presence of diffuse neutrophil infiltrates within the tumor.


Stage IIIB Adult Liver Cancer AJCC v7

description: For hepatocellular carcinoma: Stage IIIB includes: T3b, N0, M0. T3b: Single tumor or multiple tumors of any size involving a major branch of the portal vein or hepatic vein. N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 7th ed.)


name: Childhood Hepatoblastoma by Toronto Guidelines v2 Stage

description: A term that refers to the staging of childhood hepatoblastoma according to the Toronto childhood cancer staging guidelines v2.


Metastatic malignant neoplasm to liver

description: A malignant neoplasm that has spread to the liver from another (primary) anatomic site. Representative examples include carcinomas, lymphomas, melanomas, or sarcomas.


name: Stage 0 Intrahepatic Bile Duct Cancer AJCC v8

description: Stage 0 includes: Tis, N0, M0. Tis: Carcinoma in situ (intraductal tumor). N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 8th ed.)


Metastatic hepatocellular carcinoma

description: A hepatocellular carcinoma that has spread to another anatomic site.


name: Unresectable Liver and Intrahepatic Bile Duct Carcinoma

description: Liver carcinoma that is not amenable to surgical resection.


Childhood Liver Embryonal Sarcoma

description: An embryonal sarcoma of the liver that occurs during childhood.


name: Recurrent Childhood Hepatocellular Carcinoma

description: A hepatocellular carcinoma that occurs during childhood and has recurred after a period of remission.


Malignant Liver Non-Epithelial Neoplasm

description: A primary or metastatic malignant non-epithelial neoplasm that affects the liver.


name: BCLC Stage B Adult Hepatocellular Carcinoma


name: Hepatocellular Carcinoma by AJCC v8 Stage

description: A term that refers to the staging of hepatocellular carcinoma according to the American Joint Committee on Cancer, 8th edition. This staging system applies to hepatocellular carcinomas and fibrolamellar carcinomas (fibrolamellar variant of hepatocellular carcinoma). Intrahepatic cholangiocarcinomas, combined hepatocellular-cholangiocarcinomas, and sarcomas of the liver are not staged using this staging system. (from AJCC 8th Ed.)


description: A hepatocellular carcinoma that arises in a patient with a history of organ transplantation.


name: Hepatitis B Virus-Related Hepatocellular Carcinoma

description: A hepatocellular carcinoma that develops following hepatitis B virus exposure and injury of the liver parenchyma.


name: Hepatitis C Virus-Related Hepatocellular Carcinoma

description: A hepatocellular carcinoma that develops following hepatitis C virus exposure and injury of the liver parenchyma.


name: BCLC Stage 0 Adult Hepatocellular Carcinoma

description: Very early hepatocellular carcinoma. Patients are optimal candidates for resection. (HPB (Oxford) 2005; 7(1):35-41)


name: Localized Non-Resectable Adult Liver Carcinoma

description: A localized hepatocellular carcinoma or intrahepatic cholangiocarcinoma that occurs during adulthood and it is not amenable to surgical resection.


Recurrent Childhood Liver Cancer

description: A malignant neoplasm of the liver that occurs during childhood and has recurred after a period of remission.


Liver Yolk Sac Tumor

description: A yolk sac tumor that arises from the liver.


Stage I Liver Carcinoma

description: Stage I carcinoma of the liver according to the American Joint Committee on Cancer, 6th, 7th, and 8th editions.


name: Colorectal Adenocarcinoma Metastatic in the Liver

description: An adenocarcinoma that originates from the colorectal area and has spread to the liver.


name: Stage IV Hepatocellular Carcinoma AJCC v8

description: Stage IV includes: IVA: (Any T, N1, M0); IVB: (Any T, Any N, M1). N1: Regional lymph node metastasis. M0: No distant metastasis. M1: Distant metastasis. (AJCC 8th ed.)


Postsurgical Stage IV Hepatoblastoma

description: Distant metastases, regardless of the extent of liver involvement. (from PDQ 2004)


name: Localized Childhood Hepatoblastoma by Toronto Guidelines v2, Tier1

description: Tumor confined to the liver including regional lymph nodes. (Childhood cancer staging for population registries according to the Toronto Childhood Cancer Stage Guidelines - Version 2. Cancer Council Queensland and Cancer Australia: Brisbane, Australia; 2021.)


name: Small Cell Undifferentiated Hepatoblastoma

description: A hepatoblastoma composed exclusively of noncohesive sheets of small undifferentiated cells. Cases showing loss of INI1 nuclear staining should be classified as rhabdoid tumors.


name: Metastatic Childhood Hepatoblastoma by Toronto Guidelines v2, Tier 2

description: Distant metastases present. (Childhood cancer staging for population registries according to the Toronto Childhood Cancer Stage Guidelines - Version 2. Cancer Council Queensland and Cancer Australia: Brisbane, Australia; 2021.)


Postsurgical Stage I Hepatoblastoma

description: No metastases, tumor completely resected. (from PDQ 2004)


name: Well Differentiated Hepatocellular Carcinoma

description: A hepatocellular carcinoma characterized by the presence of malignant cells with mild atypia and an increased nuclear/cytoplasmic ratio forming thin trabecular patterns.  It is usually associated with small tumors and an early stage.


name: Stage IB Intrahepatic Bile Duct Cancer AJCC v8

description: Stage IB includes: T1b, N0, M0. T1b: Solitary tumor larger than 5 cm without vascular invasion. N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 8th ed.)


Childhood Fibrolamellar Carcinoma

description: A fibrolamellar variant of hepatocellular carcinoma that occurs during childhood.


Recurrent Liver Carcinoma

description: The reemergence of liver carcinoma after a period of remission.


name: Stage IVA Hepatocellular Carcinoma AJCC v8

description: Stage IVA includes: Any T, N1, M0. N1: Regional lymph node metastasis. M0: No distant metastasis. (AJCC 8th ed.)


name: BCLC Stage A Adult Hepatocellular Carcinoma

description: Early hepatocellular carcinoma.  Patients are candidates for radical therapies (resection, liver transplantation, or percutaneous treatments). (HPB (Oxford) 2005; 7(1):35-41)


Metastatic Hepatoblastoma

description: Hepatoblastoma that has spread from its original site of growth to another anatomic site.


name: Childhood Hepatoblastoma by Toronto Guidelines v2 Stage, Tier 1

description: A term that refers to the staging of childhood hepatoblastoma according to the tier 1 Toronto childhood cancer staging guidelines v2.


Stage II Adult Liver Cancer AJCC v7

description: For hepatocellular carcinoma: Stage II includes: T2, N0, M0. T2: Solitary tumor with vascular invasion or multiple tumors none more than 5 cm. N0: No regional lymph node metastasis. M0: No distant metastasis.  For intrahepatic cholangiocarcinoma: Stage II includes: T2, N0, M0. T2: Solitary tumor with vascular invasion or multiple tumors, with or without vascular invasion. N0: No regional lymph node metastasis. M0: No distant metastasis. (from AJCC 7th Ed.)


name: Stage III Childhood Hepatocellular Carcinoma AJCC v7

description: Stage III includes: IIIA: (T3a, N0, M0); IIIB: (T3b, N0, M0); IIIC: (T4, N0, M0). T3a: Multiple tumors more than 5 cm. T3b: Single tumor or multiple tumors of any size involving a major branch of the portal vein or hepatic vein.  T4: Tumors(s) with direct invasion of adjacent organs other than the gallbladder or with perforation of visceral peritoneum. N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 7th ed.)


Hepatoblastoma by PRETEXT Stage

description: A term that refers to the staging of hepatoblastoma, following the rules of the PRETEXT (pre-treatment extent of tumor) system.


Localized PRETEX I Hepatoblastoma

description: PRETEX I hepatoblastoma confined to the liver including regional lymph nodes. (Childhood cancer staging for population registries according to the Toronto Childhood Cancer Stage Guidelines - Version 2. Cancer Council Queensland and Cancer Australia: Brisbane, Australia; 2021.)


Hepatoblastoma resectable

description: Hepatoblastoma amenable to surgical removal.


name: Stage IVB Hepatocellular Carcinoma AJCC v8

description: Stage IVB includes: Any T, Any N, M1. M1: Distant metastasis. (AJCC 8th ed.)


name: Hepatocellular Carcinoma by AJCC v7 Stage

description: A term that refers to the staging of hepatocellular carcinoma according to the American Joint Committee on Cancer, 7th edition.


name: Stage IIIB Hepatocellular Carcinoma AJCC v8

description: Stage IIIB includes: T4, N0, M0. T4: Single tumor or multiple tumors of any size involving a major branch of the portal vein or hepatic vein, or tumor(s) with direct invasion of adjacent organs other than the gallbladder or with perforation of visceral peritoneum. N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 8th ed.)


name: Localized Unresectable Adult Hepatocellular Carcinoma

description: A localized hepatocellular carcinoma that occurs during adulthood and it is not amenable to surgical resection.


Adult Fibrolamellar Carcinoma

description: Fibrolamellar variant of hepatocellular carcinoma that occurs during adulthood.


name: Poorly Differentiated Hepatocellular Carcinoma

description: A hepatocellular carcinoma characterized by the presence of malignant pleomorphic cells forming solid patterns.


Recurrent Fibrolamellar Carcinoma

description: The reemergence of fibrolamellar carcinoma after a period of remission.


undifferentiated carcinoma of liver

description: A rare carcinoma that arises from the liver.  The diagnosis is made by immunohistochemical studies.  Morphologic studies alone cannot establish the diagnosis of carcinoma or further subclassify the malignant tumor.


description: A hepatocellular carcinoma that develops following alcohol-induced injury of the liver parenchyma.


name: Stage IVB Hepatocellular Carcinoma AJCC v7

description: Stage IVB includes: Any T, Any N, M1.  M1: Distant metastasis. (AJCC 7th ed.)


BCLC Stage C Hepatocellular Carcinoma

description: Advanced hepatocellular carcinoma.  Patients may receive new agents in the setting of randomized controlled trials. (HPB (Oxford) 2005; 7(1):35-41)


Stage I Adult Liver Cancer AJCC v7

description: For hepatocellular carcinoma: Stage I includes: T1, N0, M0. T1: Solitary tumor without vascular invasion. N0: No regional lymph node metastasis. M0: No distant metastasis.  For intrahepatic cholangiocarcinoma: Stage I includes: T1, N0, M0. T1: Solitary tumor without vascular invasion. N0: No regional lymph node metastasis. M0: No distant metastasis. (from AJCC 7th Ed.)


Small Hepatocellular Carcinoma

description: Hepatocellular carcinoma measuring equal to or less than 2 cm in diameter. It includes early hepatocellular carcinoma and small progressed hepatocellular carcinoma.


Hepatoblastoma by Postsurgical Stage

description: A term that refers to the staging of hepatoblastoma according to post-operative findings.


Pleomorphic Hepatocellular Carcinoma

description: A morphologic variant of hepatocellular carcinoma, characterized by the presence of malignant cells which show marked variation in their size and shape. Bizarre mononuclear or multinucleated giant cells are often present.


name: Stage IIIB Hepatocellular Carcinoma AJCC v7

description: Stage IIIB includes: T3b, N0, M0. T3b: Single tumor or multiple tumors of any size involving a major branch of the portal vein or hepatic vein.  N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 7th ed.)


Stage III Adult Liver Cancer AJCC v7

description: For hepatocellular carcinoma: Stage III includes: IIIA: (T3a, N0, M0); IIIB: (T3b, N0, M0); IIIC: (T4, N0, M0). T3a: Multiple tumors more than 5 cm. T3b: Single tumor or multiple tumors of any size involving a major branch of the portal vein or hepatic vein. T4: Tumors(s) with direct invasion of adjacent organs other than the gallbladder or with perforation of visceral peritoneum. N0: No regional lymph node metastasis. M0: No distant metastasis.  For intrahepatic cholangiocarcinoma: Stage III includes: T3, N0, M0. T3: Tumor perforating the visceral peritoneum or involving the local extra hepatic structures by direct invasion. N0: No regional lymph node metastasis. M0: No distant metastasis. (from AJCC 7th Ed.)


name: large cell neuroendocrine carcinoma of liver

description: An aggressive, high-grade and poorly differentiated carcinoma with neuroendocrine differentiation that arises from the liver. It is characterized by the presence of malignant large cells.


PRETEXT I Hepatoblastoma

description: An internationally developed presurgical anatomic staging system using imaging techniques: Tumor involves only 1 quadrant; 3 adjoining liver quadrants are free of tumor. (from PDQ 2004)


name: Hepatocellular Carcinoma by AJCC v6 Stage

description: A term that refers to the staging of hepatocellular carcinoma according to the American Joint Committee on Cancer, 6th edition.


Childhood Liver Angiosarcoma

description: An angiosarcoma that arises from the liver during childhood. Most cases arise within preexisting liver infantile hemangiomas.


Epithelial Hepatoblastoma

description: A subtype of hepatoblastoma characterized by the presence of an epithelial component and absence of mesenchymal elements. It includes hepatoblastoma with pure fetal epithelial differentiation, hepatoblastoma with combined fetal and embryonal epithelial differentiation, macrotrabecular hepatoblastoma, and small cell undifferentiated hepatoblastoma (small cell undifferentiated hepatoblastoma with loss of INI1 nuclear staining should be classified as rhabdoid tumor).


Hepatocellular Carcinoma by BCLC Stage

description: A staging classification system for hepatocellular carcinoma that uses variables related to tumor stage, liver functional status, physical status, and cancer-related symptoms, and links the stages with a treatment algorithm. (HPB (Oxford) 2005; 7(1):35-41)


name: Metastatic Childhood Hepatoblastoma by Toronto Guidelines v2, Tier 1

description: Distant metastases present. (Childhood cancer staging for population registries according to the Toronto Childhood Cancer Stage Guidelines - Version 2. Cancer Council Queensland and Cancer Australia: Brisbane, Australia; 2021.)


Hepatoblastoma non-resectable

description: Hepatoblastoma not amenable to surgical removal.


name: Intrahepatic Bile Duct Cancer by AJCC v8 Stage

description: A term that refers to the staging of intrahepatic bile duct cancer according to the American Joint Committee on Cancer, 8th edition. This staging system applies to intrahepatic cholangiocarcinomas, combined hepatocellular-cholangiocarcinomas (mixed hepatocholangiocarcinomas), and primary neuroendocrine tumors of the liver. Primary sarcomas of the liver, pure hepatocellular carcinomas, hilar cholangiocarcinomas, and gallbladder carcinomas are not staged using this staging system. (from AJCC 8th Ed.)


name: Stage III Intrahepatic Bile Duct Cancer AJCC v8

description: Stage III includes: IIIA: (T3, N0, M0); IIIB: (T4, N0, M0); (Any T, N1, M0). T3: Tumor perforating the visceral peritoneum. T4: Tumor involving local extrahepatic structures by direct invasion. N0: No regional lymph node metastasis. N1: Regional lymph node metastasis. M0: No distant metastasis. (AJCC 8th ed.)


Chromophobe Hepatocellular Carcinoma

description: Hepatocellular carcinoma characterized by the presence of malignant cells with smooth chromophobic cytoplasm, abrupt focal nuclear anaplasia, and scattered microscopic pseudocysts.


Recurrent Hepatocellular Carcinoma

description: The reemergence of hepatocellular carcinoma after a period of remission


BCLC Stage A Hepatocellular Carcinoma

description: Early hepatocellular carcinoma.  Patients are candidates for radical therapies (resection, liver transplantation, or percutaneous treatments). (HPB (Oxford) 2005; 7(1):35-41)


Refractory Liver Carcinoma

description: Liver carcinoma that is resistant to treatment.


Stage IVB Liver Cancer

description: Stage IVB carcinoma of the liver according to the American Joint Committee on Cancer, 7th and 8th editions.


Metastatic PRETEX III Hepatoblastoma

description: PRETEX III hepatoblastoma with distant metastases. (Childhood cancer staging for population registries according to the Toronto Childhood Cancer Stage Guidelines - Version 2. Cancer Council Queensland and Cancer Australia: Brisbane, Australia; 2021.)


Refractory Hepatocellular Carcinoma

description: Hepatocellular carcinoma that is resistant to treatment.


Localized PRETEX II Hepatoblastoma

description: PRETEX II hepatoblastoma confined to the liver including regional lymph nodes. (Childhood cancer staging for population registries according to the Toronto Childhood Cancer Stage Guidelines - Version 2. Cancer Council Queensland and Cancer Australia: Brisbane, Australia; 2021.)


Metastatic carcinoma to liver

description: A carcinoma that has spread to the liver from another primary anatomic site.  Representative examples include metastatic carcinomas from the colon, breast, and lung.


name: Localized Childhood Hepatoblastoma by Toronto Guidelines v2, Tier 2

description: Tumor confined to the liver including regional lymph nodes. (Childhood cancer staging for population registries according to the Toronto Childhood Cancer Stage Guidelines - Version 2. Cancer Council Queensland and Cancer Australia: Brisbane, Australia; 2021.)


Early Hepatocellular Carcinoma

description: A low grade, well differentiated small hepatocellular carcinoma. It lacks obvious stromal invasion and significant atypia.


Metastatic PRETEX IV Hepatoblastoma

description: PRETEX IV hepatoblastoma with distant metastases. (Childhood cancer staging for population registries according to the Toronto Childhood Cancer Stage Guidelines - Version 2. Cancer Council Queensland and Cancer Australia: Brisbane, Australia; 2021.)


Liver Plasmacytoma

description: A plasmacytoma that arises in the liver.


name: Stage II Hepatocellular Carcinoma AJCC v6 and v7

description: Stage II includes: T2, N0, M0.  T2: Solitary tumor with vascular invasion or multiple tumors none more than 5 cm.  N0: No regional lymph node metastasis.  M0: No distant metastasis. (AJCC 6th and 7th eds.)


description: A rare type of hepatocellular carcinoma characterized by the presence of pleomorphic malignant cells that are intermixed with lymphocytes.


name: Stage III Hepatocellular Carcinoma AJCC v6

description: Stage III includes: IIIA: (T3, N0, M0); IIIB: (T4, N0, M0); IIIC: (Any T, Any N, M0).  IIIA: T3: Multiple tumors more than 5 cm or tumor involving a major branch of the portal or hepatic vein(s).  T4: Tumors(s) with direct invasion of adjacent organs other than the gallbladder or with perforation of visceral peritoneum.  N0: No regional lymph node metastasis.  N1: Regional lymph node metastasis.  M0: No distant metastasis. (AJCC 6th ed.)


PRETEXT II Hepatoblastoma

description: An internationally developed presurgical anatomic staging system using imaging techniques: Tumor involves 2 adjoining quadrants; 2 adjoining quadrants are free of tumor. (from PDQ 2004)


Stage IV Adult Liver Cancer AJCC v7

description: For hepatocellular carcinoma: Stage IV includes: IVA: (Any T, N1, M0); IVB: (Any T, Any N, M1). N1: Regional lymph node metastasis. M0: No distant metastasis. M1: Distant metastasis.  For intrahepatic cholangiocarcinoma: Stage IVA includes: (T4, N0, M0); (Any T, N1, M0). T4: Tumor with periductal invasion. N0: No regional lymph node metastasis. N1: Regional lymph node metastasis. M0: No distant metastasis.  Stage IVB includes: Any T, Any N, M1. M1: Distant metastasis. (from AJCC 7th Ed.)


Unresectable Hepatocellular Carcinoma

description: A hepatocellular carcinoma that is not amenable to surgical resection.


name: Hepatoblastoma with Combined Fetal and Embryonal Epithelial Differentiation

description: A hepatoblastoma composed of cells resembling fetal epithelial cells and small round cells resembling blastema cells.


name: Rectal Carcinoma Metastatic in the Liver

description: A carcinoma that originates from the rectum and has spread to the liver.


name: Adult Combined Hepatocellular Carcinoma and Cholangiocarcinoma

description: A combined hepatocellular carcinoma and cholangiocarcinoma that occurs during adulthood.


name: Stage IIIA Hepatocellular Carcinoma AJCC v8

description: Stage IIIA includes: T3, N0, M0. T3: Multiple tumors, at least one of which is larger than 5 cm. N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 8th ed.)


name: Stage IIIC Hepatocellular Carcinoma AJCC v7

description: Stage IIIC includes: T4, N0, M0.  T4: Tumors(s) with direct invasion of adjacent organs other than the gallbladder or with perforation of visceral peritoneum. N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 7th ed.)


Childhood Malignant Liver Neoplasm

description: A malignant neoplasm that affects the liver and occurs during childhood.


name: BCLC Stage D Adult Hepatocellular Carcinoma

description: End-stage hepatocellular carcinoma.  Patients will receive symptomatic treatment. (HPB (Oxford) 2005; 7(1):35-41)


name: Macrotrabecular Massive Hepatocellular Carcinoma

description: Hepatocellular carcinoma characterized by more than 50% growth of macrotrabecular pattern (equal to or more than 6 to 10 cells thick). It presents with higher grade and stage compared to conventional hepatocellular carcinoma. It has poor prognosis with early recurrence and poor overall survival.


name: Stage II Childhood Hepatocellular Carcinoma AJCC v6 and v7


Metastatic PRETEX II Hepatoblastoma

description: PRETEX II hepatoblastoma with distant metastases. (Childhood cancer staging for population registries according to the Toronto Childhood Cancer Stage Guidelines - Version 2. Cancer Council Queensland and Cancer Australia: Brisbane, Australia; 2021.)


Early Stage Hepatocellular Carcinoma

description: A stage term referring to hepatocellular carcinoma that presents as a single tumor with the largest diameter measuring 2 cm or less. The liver function is well-preserved and there is no vascular invasion or metastasis. (Barcelona Liver Cancer Classification).


name: Stage IIIB Intrahepatic Bile Duct Cancer AJCC v8

description: Stage IIIB includes: (T4, N0, M0); (Any T, N1, M0). T4: Tumor involving local extrahepatic structures by direct invasion. N0: No regional lymph node metastasis. N1: Regional lymph node metastasis. M0: No distant metastasis. (AJCC 8th ed.)


description: Hepatocellular carcinoma characterized by the presence of steatohepatitis features, including macrovesicular steatosis, fibrosis, ballooning of malignant hepatocytes, Mallory bodies, and inflammation.


name: Colorectal Carcinoma Metastatic in the Liver

description: A carcinoma that originates from the colorectal area and has spread to the liver.


Metastatic PRETEX I Hepatoblastoma

description: PRETEX I hepatoblastoma with distant metastases. (Childhood cancer staging for population registries according to the Toronto Childhood Cancer Stage Guidelines - Version 2. Cancer Council Queensland and Cancer Australia: Brisbane, Australia; 2021.)


name: Small Progressed Hepatocellular Carcinoma

description: A well to moderately differentiated small hepatocellular carcinoma. It is characterized by the presence of obvious stromal invasion and increase atypia compared with early hepatocellular carcinoma.


Recurrent Adult Liver Carcinoma

description: A hepatocellular carcinoma or intrahepatic cholangiocarcinoma that occurs during adulthood and has recurred after a period of remission.


yanuthone F

A class I yanuthone that is 7-deacetoxyyanuthone A in which one of the hydrogens of the trans-terminal methyl groups of the sesquiterpenoid side-chain has been replaced by a hydroxy group.


Grade 3 Joint Infection, CTCAE

category: biolink:PhenotypicFeature biolink:DiseaseOrPhenotypicFeature biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing

description: Arthroscopic intervention indicated (e.g., drainage) or arthrotomy (e.g., open surgical drainage)


2,6-dioxo-6-phenylhexanoic acid

A dioxo monocarboxylic acid consisting of 6-phenylhexanoic acid having the two oxo groups at the 2- and 6-positions.


name: Grade II Prostatic Intraepithelial Neoplasia

description: High grade prostatic intraepithelial neoplasia characterized by the presence of moderate architectural and cytologic abnormalities.


ROS1 Negative

description: An indication that expression of ROS1 has not been detected in a sample.


name: Testicular Tumor of the Thecoma/Fibroma Group

description: A group of rare, slow-growing stromal tumors that arise from the testis.  This category includes thecoma and fibroma.


Testicular Signet Ring Stromal Tumor

description: An extremely rare tumor that arises from the testis. It is characterized by the proliferation of epithelioid cells with signet ring appearance separated by fibrous tissue into trabeculae and nests. The histologic features are bland and there is no mucin production. Mutations of CTNNB1 gene have been identified in the reported cases. It is considered a special type of sex cord-stromal tumor. All reported cases had a benign clinical course without metastases.


name: recurrent childhood acute myeloid leukemia

description: The reemergence of acute myeloid leukemia in childhood after a period of remission.


Arg-Ile

A dipeptide formed from L-arginyl and L-isoleucine residues.


A phosphatidylethanolamine 34:0 zwitterion in which the acyl groups at positions 1 and 2 are both specified as heptadecanoyl.


A 1,2-diacyl-sn-glycero-3-phosphoethanolamine zwitterion in which the acyl groups at C-1 and C-2 contain 34 carbons in total with 0 double bonds.


A phosphatidylethanolamine 34:1 zwitterion obtained by transfer of a proton from the phosphate to the amino group of 1-hexadecanoyl-2-octadecanoyl-sn-glycero-3-phosphoethanolamine.


(-)-coronaridine

A monoterpenoid indole alkaloid with formula C21H26N2O2. It is isolated from the flowering plant genus, Tabernaemontana.


Oropharyngeal Cancer pT3 TNM Finding v7

description: Oropharyngeal cancer with tumor size more than 4 centimeters in greatest dimension or extension to lingual surface of epiglottis. (from AJCC 7th Ed.)


A secondary fatty alcohol that is hexacosane substituted by a hydroxy group at position 13.


name: Stage IV Gestational Trophoblastic Neoplasm AJCC v8

description: Stage IV includes: Any T, M1b. M1b: Gestational trophoblastic neoplasm with all other distant metastases. (AJCC 8th Ed.)


Grade 4 Uterine Hemorrhage, CTCAE

description: Life-threatening consequences; urgent intervention indicated


name: Childhood Unfavorable Prognosis Hodgkin Lymphoma

description: A Hodgkin lymphoma with unfavorable prognosis that occurs during childhood.


Acquired Factor III Deficiency

description: An acquired coagulation disorder characterized by the partial or complete absence of tissue factor (factor III) activity in the blood.


Factor III deficiency

description: A coagulation disorder characterized by the partial or complete absence of tissue factor (factor III) activity in the blood.


Factor III Inactivation

description: Presence of inactivating antibodies to tissue factor (factor III) in the blood.


Hereditary Factor III Deficiency

description: An autosomal recessive, inherited coagulation disorder characterized by the partial or complete absence of tissue factor (factor III) activity in the blood.


A member of the class of 1,3-benzoxazoles that is 1,3-benzoxazole substituted at positions 2 and 5 by 4-ethylphenyl and 3-nitrobenzamido groups respectively.


Parallel Imaging Artifact

description: Artifacts that are produced when acquisition times are reduced and some signals are computed rather than acquired.


name: Grade 4 Nodal or Junctional Rhythm, CTCAE


Acardius

description: A severe form of twin-twin transfusion syndrome that occurs in monochorionic pregnancies. The normal twin (pump twin) supplies the blood flow to its sibling that lacks heart or brain or both (acardiac/acephalic twin). Untreated, it may lead to the demise of the pump twin in some cases.


Suture Abrasion

description: Wearing away of the surface of a suture as a result of bending and frictional forces.


skin abrasion

description: Superficial damage to the skin caused by rubbing or scraping.


Parkinson Disease 9

description: An autosomal recessive subtype of Parkinson disease, caused by mutation(s) in the ATP13A2 gene, encoding polyamine-transporting ATPase 13A2.


name: Parkinson Disease 23, Autosomal Recessive, Early Onset

description: An autosomal recessive subtype of Parkinson disease, caused by mutation(s) in the VPS13C gene, encoding intermembrane lipid transfer protein VPS13C.


Parkinson Disease 20, Early-Onset

description: An autosomal recessive subtype of Parkinson disease, caused by mutation(s) in the SYNJ1 gene, encoding synaptojanin-1.


Grade 5 Necrotizing Enterocolitis, AE

description: A necrotizing enterocolitis adverse event in a newborn which results in death.


desertorin A

A bicoumarin that is 7-hydroxy-4-methoxy-5-methyl-2H-chromen-2-one substituted by a 7-hydroxy-4-methoxy-5-methyl-2-oxo-2H-chromen-6-yl group at position 8.


name: Grade 3 Jugular Vein Intra-Operative Injury, CTCAE


isotridecanoyl-CoA

A methyl-branched fatty acyl-CoA obtained from the formal condensation of the thiol group of coenzyme A with the carboxy group of isotridecanoic acid


Benign neoplasm of supraglottis

description: A neoplasm that arises from the supraglottis and is characterized by the absence of atypical or malignant cytological and architectural features, and absence of invasive features or metastatic potential.


name: Childhood Acute Myeloid Leukemia without Maturation

description: An acute myeloid leukemia without maturation occurring in children.


A member of the class of anthracyclines that is beta-rhodomycin lacking the phenolic hydroxy group at position 11.


Grade 3 Tracheal Fistula, CTCAE

description: Invasive intervention indicated


name: Pulmonary and Upper Respiratory Fistula, CTCAE


Grade 3 Laryngeal Fistula, CTCAE

description: Invasive intervention indicated


name: Grade 1 Oral Cavity Pulmonary Fistula, CTCAE


Grade 2 Laryngeal Fistula, CTCAE

description: Symptomatic, invasive intervention not indicated


name: Grade 3 Oral Cavity Pulmonary Fistula, CTCAE


Laryngeal Fistula, CTCAE

description: A disorder characterized by an abnormal communication between the larynx and another organ or anatomic site.


name: Grade 4 Pharynx Pulmonary Fistula, CTCAE


name: Grade 4 Oral Cavity Pulmonary Fistula, CTCAE


Tracheal Fistula, CTCAE

description: A disorder characterized by an abnormal communication between the trachea and another organ or anatomic site.


Grade 5 Laryngeal Fistula, CTCAE

description: Death


Grade 4 Laryngeal Fistula, CTCAE

description: Life-threatening consequences; urgent intervention indicated


name: Grade 5 Oral Cavity Pulmonary Fistula, CTCAE


name: Grade 5 Pharynx Pulmonary Fistula, CTCAE


name: Grade 3 Pharynx Pulmonary Fistula, CTCAE


Grade 1 Laryngeal Fistula, CTCAE

description: Asymptomatic


Grade 1 Tracheal Fistula, CTCAE

description: Asymptomatic


name: Grade 2 Pharynx Pulmonary Fistula, CTCAE


name: Grade 1 Pharynx Pulmonary Fistula, CTCAE


That one of the three tautomers of pyrrole which has the double bonds at positions 1 and 4.


Parasite-Related Carcinoma

description: A term that refers to a group of carcinomas that are caused by parasites.


name: Schistosoma Hematobium-Related Bladder Squamous Cell Carcinoma

description: A squamous cell carcinoma of the bladder that is caused by Schistosoma hematobium.


name: Schistosoma Hematobium-Related Bladder Verrucous Carcinoma

description: A verrucous squamous cell carcinoma of the bladder that is caused by Schistosoma hematobium.


A secondary carboxamide resulting from the formal condensation of the carboxy group of 4-sulfamoylbenzoic acid with the amino group of 1-phenylmethanamine. It is a potent inhibitor of carbonic anhydrase II.


Thymic Tumor pT1b TNM Finding v8

description: Thymic tumor with direct invasion of mediastinal pleura. (from AJCC 8th Ed.)


pyrylium salt

Any salt of pyrylium or its derivatives


name: Occlusion and Stenosis of Right Vertebral Artery

description: Evidence of occlusion and stenosis of right vertebral artery.


Felty's Syndrome, Right Knee

description: Evidence of Felty's syndrome in the right knee.


1,2-diacyl-sn-glycero-3-phosphoethanolamine zwitterion in which the acyl groups at positions 1 and 2 are both specified as hexanoyl.


(S)-idazoxan

An idazoxan that has S configuration.


Aortic Valve Regurgitant Fraction

description: A quantitative measurement of the amount of retrograde blood flow across the orifice of the aortic valve expressed as a percentage of the anterograde flow.


4-O-methyl-L-dopa zwitterion

An aromatic L-alpha-amino acid zwitterion resulting from transfer of a proton from the carboxy to the amino group of 4-O-methyl-L-dopa. Major species at pH 7.3


aromatic L-alpha-amino acid zwitterion

An L-alpha-amino acid zwitterion resulting from a transfer of a proton from the carboxy to the amino group of any aromatic L-alpha-amino acid; major species at pH 7.3.


L-6'-bromotryptophan zwitterion

The L-alpha-amino acid zwitterion that results from the transfer of a proton from the carboxylic acid group to the alpha-amino group of L-6'-bromotryptophan. The major species at pH 7.3.


3-O-methyldopa zwitterion

An aromatic L-alpha-amino acid zwitterion resulting from transfer of a proton from the carboxy to the amino group of 3-O-methyldopa. Major species at pH 7.3


calysolin III

A resin glycoside that is the pentasaccharide derivative of  jalapinolic acid. It has been isolated from Calystegia soldanella.


A glucotriose consisting of beta-D-glucopyranosyl, alpha-D-glucopyranosyl and D-glucopyranoseresidues joined in sequence by two (1->4) glycosidic linkages.


name: Metastatic malignant neoplasm to choroid

description: A malignant neoplasm that has spread to the choroid from another anatomic site.


A ceramide phosphoethanolamine zwitterion obtained by transfer of a proton from the phospho to the amino group of any N-acyltetradecasphingosine-1-phosphoethanolamine; major species at pH 7.3.


name: Type 2 Diabetes Mellitus with Proliferative Diabetic Retinopathy with Macular Edema

description: Evidence of type 2 diabetes mellitus with proliferative diabetic retinopathy with macular edema.


Gallbladder Soft Tissue Neoplasm

description: A benign, intermediate, or malignant mesenchymal neoplasm that arises from the gallbladder.


Uterus Present

description: An indication that an individual's uterus is present.


2-(2-methylthioethyl)malic acid

The 2-(2-methylthioethyl) derivative of malic acid.


iron trichloride hexahydrate

A hydrate that is the hexahydrate form of iron trichloride.


flufiprole

A racemate comprising equimolar amounts of (R)- and (S)-flufiprole. It is a phenylpyrazole insecticide used to control brown plant hopper and leafy beetle in rice.


lactonamycin

An organic heterohexacyclic compound isolated from the culture broth of Streptomyces rishiriensis. It is an antibiotic with antibacterial activity.


name: Type 1 Diabetes Mellitus with Proliferative Diabetic Retinopathy without Macular Edema, Unspecified Eye

description: Evidence of type 1 diabetes mellitus with proliferative diabetic retinopathy without macular edema in an unspecified eye.


Childhood Osteochondroma

description: An osteochondroma that occurs during childhood.


Osteochondromatosis

description: An autosomal dominant neoplastic chondrogenic process affecting multiple sites. It is caused by mutations in the EXT1 or EXT2 genes.  Grossly and microscopically, the lesions resemble an osteochondroma.


Maxillofacial Osteochondroma

description: A rare osteochondroma that arises from a maxillofacial bone.


Childhood Chondroblastoma

description: A chondroblastoma that occurs during childhood.


Maxillofacial Chondroblastoma

description: A benign chondroid-producing neoplasm arising in a maxillofacial bone.


Jaw Chondromyxoid Fibroma

description: A chondromyxoid fibroma that arises from the jaw.


Laryngeal Chondroma

description: A benign neoplasm arising from hyaline cartilage of the larynx. It is characterized by the presence of chondrocytes, a lobulated growth pattern, and calcification.


Maxillofacial Chondroma

description: A benign neoplasm of hyaline cartilage that arises within the medullary cavity of a maxillofacial bone. It is characterized by the presence of chondrocytes, a lobulated growth pattern, and calcification.


Childhood Chondromyxoid Fibroma

description: A chondromyxoid fibroma that occurs during childhood.


Childhood Subungual Exostosis

description: Subungual exostosis that occurs during childhood.


Maxillofacial Chondromyxoid Fibroma

description: An uncommon benign cartilaginous neoplasm arising in a maxillofacial bone. It is characterized by the presence of spindle-shaped or stellate chondrocytes, a lobulated growth pattern, myxoid stroma formation, and sometimes multinucleated giant cells.


Chondromatosis

description: A multifocal benign neoplasm arising from bone or soft tissue.  It is characterized by the presence of chondrocytes and is composed of hyaline cartilage.


name: Bizarre parosteal osteochondromatous proliferation

description: A benign lesion that usually affects the proximal small bones of the hands or feet.  Grossly it consists of a cartilage cap and a bony stalk.  Microscopically it is characterized by the presence of spindle cells, cartilage, and bone, usually in a disorganized pattern compared to subungual exostosis.  Enlarged (bizarre) chondrocytes are present in the cartilage.  Swelling with or without pain is present.  Recurrences following resection have been reported in approximately half of cases.


Solitary Osteochondroma

description: An osteochondroma affecting a single anatomical site.


A 2-aminohexano-6-lactam derived from L-lysine.


A sterol ester that is the O-succinoyl derivative of 3beta-hydroxy-5alpha-pregnan-20-one.


hemisuccinate

A succinate ester in which only one of the carboxy groups of succinic acid has been esterified.


O-succinyl-L-serine

A dicarboxylic acid monoester obtained by formal condensation of one of the carboxy groups of succinic acid with the side-chain hydroxy group of L-serine. It is an intermediate in the biosynthesis of the amino acid cysteine in fungi and bacteria.


6beta-hydroxyprogesterone hemisuccinate

A dicarboxylic acid monoester that is the hydrogen succinate ester of 6beta-hydroxyprogesterone.


A dicarboxylic acid monoester that is the 21-(hydrogen succinate) derivative of 11-deoxycorticosterone.


O-succinyl-L-homoserine

The O-succinyl derivative of L-homoserine.


A dicarboxylic acid monoester that is succinic acid monoesterified with 6-endo-amino-6-exo-benzoyl-5-exo-phenylnorbornan-2-ol


O-succinylcarnitine

An O-acylcarnitine having succinyl as the acyl substituent.


monomethyl succinate

A dicarboxylic acid monoester that is succinic acid in which one of the carboxy groups has been converted to its methyl ester.


A sterol ester that is the O-succinoyl derivative of 3beta-hydroxy-5beta-pregnan-20-one.


A steroid ester that is the O-succinoyl derivative of 11alpha-hydroxyprogesterone.


A nucleotide-sugar having ADP as the nucleotide fragment and 2-O-succinyl-D-ribofuranos-5-yl as the sugar component.


hydrocortisone succinate

A derivative of succinic acid in which one of the carboxy groups is esterified by the C-21 hydroxy group of cortisol (hydrocortisone).


etiocholanolone hemisuccinate

A sterol ester that is the O-succinoyl derivative of etiocholanolone.


Uterine Obstruction

description: Blockage of the uterine outlet. Causes include uterine tumors and adhesions.


Tactile Disorder

description: Conditions characterized by an alteration in the ability to perceive touch.


Protein kinase inhibitor of SNF1 analog sensitive allele.


A member of the class of 2,6-diaminopurines that is 2,6-diamiopurine which is substituted by an isopropyl group at position 9 and in which the amino groups at positions 2 and 6 are substituted by a 1-hydroxybutan-2-yl and 3-(pyridin-2-yl)phenyl groups, respectively (the R enantiomer). A cyclin dependent kinase inhibitor, widely used as its hydrochloride hydrate.


BETHANECHOL CHLORIDE

The chloride salt of bethanechol. A slowly hydrolysed muscarinic agonist with no nicotinic effects, it is used to increase smooth muscle tone, as in the gastrointestinal tract following abdominal surgery, treatment of gastro-oesophageal reflux disease, and as an alternative to catheterisation in the treatment of non-obstructive urinary retention.


(S)-bethanechol chloride

The (S)-enantiomer of bethanechol chloride.


Refractory Lymphoma

description: A lymphoma that does not respond to treatment.


name: Refractory Central Nervous System Lymphoma

description: Central nervous system lymphoma that is resistant to treatment.


Refractory Primary Cutaneous Lymphoma

description: Primary cutaneous lymphoma that does not respond to treatment.


Refractory EBV-Related Lymphoma

description: EBV-related lymphoma that is resistant to treatment.


name: Hodgkin's disease mixed cellularity refractory

description: Mixed cellularity classic Hodgkin lymphoma that is resistant to treatment.


Classical Hodgkin lymphoma refractory

description: Classic Hodgkin lymphoma that is resistant to treatment.


Refractory Primary Bone Lymphoma

description: Primary lymphoma of bone that is resistant to treatment.


Refractory Hodgkin Lymphoma

description: Hodgkin lymphoma resistant to treatment


name: Hodgkin's disease nodular sclerosis refractory

description: Nodular sclerosis classic Hodgkin lymphoma that is resistant to treatment.


name: Refractory Lymphocyte-Rich Classic Hodgkin Lymphoma

description: Lymphocyte-rich classic Hodgkin lymphoma that does not respond to treatment.


name: Hodgkin's disease lymphocyte depletion type refractory

description: Lymphocyte-depleted classic Hodgkin lymphoma that is resistant to treatment.


A potent cell-permeable and bivalent Smac mimetic which binds to XIAP, cIAP-1 and cIAP-2 proteins (Ki = 0.56 nM,  0.31 nM and 1.1 nM, respectively). It induces apoptosis and tumor regression in cancer xenograft models.


A glycol that is 2-methylpropane in which the two hydroxy groups are located at positions 1 and 2..


Sinonasal Neuroendocrine Tumor G2

description: A well-differentiated, intermediate grade neuroendocrine neoplasm that arises from the nasal cavity or paranasal sinuses.


Head and Neck Neuroendocrine Tumor

description: A well-differentiated, low or intermediate grade neuroendocrine neoplasm that arises from the head and neck.


Laryngeal Neuroendocrine Tumor G1

description: A well-differentiated, low grade neuroendocrine neoplasm that arises from the larynx.


Sinonasal Neuroendocrine Tumor

description: A well-differentiated, low or intermediate grade neuroendocrine neoplasm that arises from the sinonasal tract.


Head and Neck Neuroendocrine Tumor G2

description: A well-differentiated, intermediate grade neuroendocrine neoplasm that arises from the head and neck.


Paranasal Sinus Neuroendocrine Tumor G1

description: A well-differentiated, low grade neuroendocrine neoplasm that arises from the paranasal sinuses.


Paranasal Sinus Neuroendocrine Tumor

description: A well-differentiated, low or intermediate grade neuroendocrine neoplasm that arises from the paranasal sinuses.


Nasal Cavity Neuroendocrine Tumor G2

description: A well-differentiated, intermediate grade neuroendocrine neoplasm that arises from the nasal cavity.


Nasal Cavity Neuroendocrine Tumor

description: A well-differentiated, low or intermediate grade neuroendocrine neoplasm that arises from the nasal cavity.


Laryngeal Neuroendocrine Tumor

description: A well-differentiated, low or intermediate grade neuroendocrine neoplasm that arises from the larynx.


Nasal Cavity Neuroendocrine Tumor G1

description: A well-differentiated, low grade neuroendocrine neoplasm that arises from the nasal cavity.


Sinonasal Neuroendocrine Tumor G1

description: A well-differentiated, low grade neuroendocrine neoplasm that arises from the nasal cavity or paranasal sinuses.


Head and Neck Neuroendocrine Tumor G1

description: A well-differentiated, low grade neuroendocrine neoplasm that arises from the head and neck.


Laryngeal Neuroendocrine Tumor G2

description: A well-differentiated, intermediate grade neuroendocrine neoplasm that arises from the larynx.


A 1,2-diacyl-sn-glycero-3-phosphoethanolamine zwitterion in which the two acyl groups contain a total of 18 carbons and no double bonds.


lucifer yellow carbohydrazide dye

An organic dilithium salt having 6-amino-2-[(hydrazinocarbonyl)amino]-1,3-dioxo-2,3-dihydro-1H-benzo[de]isoquinoline-5,8-disulfonate as the counterion.


nafarelin acetate

An acetate salt obtained by reaction of nafarelin with one equivalent of acetic acid.


Post abortion hemorrhage

description: Excessive bleeding occurring after spontaneous miscarriage or therapeutic abortion.


An alpha-galactosylceramide in which the nitrogen carries a hexacosanamido group and C-4 carries in addition to a hydroxy function a 4-phenylbutyl group. Essentially a phytosphingosine analogue with a truncated lipid chain terminating in a benzene ring, it has been used in investigations on the binding affinity of glycolipids to CD1d molecules.


The (R,R)-stereoisomer of 2-methyl-6-phytylhydroquinone.


A member of the class of hydroquinones that is 2-methylbenzene-1,4-diol substituted by a phytyl group at position 6.


6-acetamido-3-oxohexanoic acid

A 3-oxo monocarboxylic acid that is 3-oxohexanoic acid substituted at position 6 by an acetamido group.


name: Grade 4 Intestinal Stoma Obstruction, CTCAE

description: Life-threatening consequences; urgent operative intervention indicated


name: Refractory Bladder Small Cell Neuroendocrine Carcinoma

description: Bladder small cell neuroendocrine carcinoma that is resistant to treatment.


A macromolecule composed of repeating 2,6-dimethyl-1,4-phenyleneoxy units.


name: 18,25-dihydroxyvitamin D3 / 18,25-dihydroxycholecalciferol


vitamin D4

It is present in mushrooms.


name: 1alpha,25-dihydroxy-11alpha-methoxyvitamin D3 / 1alpha,25-dihydroxy-11alpha-methoxycholecalciferol


name: 1alpha,25-dihydroxy-2beta-(6-hydroxyhexyl)vitamin D3 / 1alpha,25-dihydroxy-2beta-(6-hydroxyhexyl)cholecalciferol


name: 1,25-dihydroxy-22-oxavitamin D3 3-hemiglutarate/ 1,25-dihydroxy-22-oxacholecalciferol 3-hemiglutarate


name: (6R)-vitamin D2 6,19-sulfur dioxide adduct / (6R)-ergocalciferol 6,19-sulfur dioxide adduct


previtamin D3

A hydroxy seco-steroid which is an intermediate in the production of vitamin D3 in human skin.


23(S),25-dihydroxy-24-oxovitamin D3

A hydroxycalciol that is 25-hydroxyvitamin D3 carrying an additional hydroxy group at position 23 (with 23S-configuration) and an oxo group at position 24. An intermediate in the degradation pathway of 25-OH-vitamin D3.


name: 24-(dimethoxyphosphoryl)-25,26,27-trinorvitamin D3 / 24-(dimethoxyphosphoryl)-25,26,27-trinorcholecalciferol


name: 24-fluoro-25-hydroxyvitamin D3 / 24-fluoro-25-hydroxycholecalciferol


(20S,24S)-dihydroxyvitamin D3

A hydroxycalciol that consists of vitamin D3 (calciol) carrying additional hydroxy groups at positions 20 and 24 (both with S-configuration).


name: 2alpha-chloro-1beta,25-dihydroxyvitamin D3 / 2alpha-chloro-1beta,25-dihydroxycholecalciferol


name: (20S)-1alpha,20,25-trihydroxy-24a-homovitamin D3 / (20S)-1alpha,20,25-trihydroxy-24a-homocholecalciferol


name: (6R)-vitamin D3 6,19-(4-phenyl-1,2,4-triazoline-3,5-dione) adduct


name: (24R)-6,19-epidioxy-1,24-dihydroxy-6,19-dihydrovitamin D3 / (24R)-6,19-epidioxy-1,24-di hydroxy-6,19-dihydrocholecalciferol


name: 1alpha,25-dihydroxy-24-oxo-23-azavitamin D2 / 1alpha,25-dihydroxy-24-oxo-23-azaergocalciferol


name: (24R,25S)-25,26-epoxy-1alpha,24-dihydroxyvitamin D3 / (24R,25S)-25,26-epoxy-1alpha,24-dihydroxycholecalciferol


name: (23R)-1alpha,23,25-trihydroxy-23-methylvitamin D3 / (23R)-1alpha,23,25-trihydroxy-23-methylcholecalciferol


name: 25-hydroxy-16,17-didehydrovitamin D3 / 25-hydroxy-16,17-didehydrocholecalciferol


name: 1alpha,25-dihydroxy-18-oxovitamin D3 / 1alpha,25-dihydroxy-18-oxocholecalciferol


calcidiol 3-O-(beta-D-glucuronide)

A steroid glucosiduronic acid that is calcidiol in which the hydroxy hydrogen at position 3 has been replaced by a beta-D-glucuronyl residue.


name: 1alpha,25-dihydroxy-11alpha-(hydroxymethyl)vitamin D3 / 1alpha,25-dihydroxy-11alpha-(hydroxymethyl)cholecalciferol


name: 1alpha,24,25,28-tetrahydroxyvitamin D2 / 1alpha,24,25,28-tetrahydroxyergocalciferol


name: 1alpha,25-dihydroxy-(26,26)-(27,27)-diethanovitamin D3 / 1alpha,25-dihydroxy-(26,26)-(27,27)-diethanocholecalciferol


1,24(S)-dihydroxyvitamin D2

Metabolite of vitamin D2. It  present in the circulation of humans, cows, and rats given pharmacologic doses of vitamin D2


A hydroxycalciol that is a synthetic analogue of vitamin D3 which contains an oxolane ring and exhibits weak vitamin D receptor agonist activity.


(20S)-hydroxyvitamin D3

A hydroxycalciol that consists of vitamin D3 (calciol) carrying an additional hydroxy group at position 20 with S-configuration.


18-acetoxy-1alpha-hydroxyvitamin D3

A hydroxycalciol that is calciol with an additional hydroxy group at position C-1 and an acetoxy group at C-18.


name: 1alpha,25-dihydroxy-24a,24b-dihomo-23-oxavitamin D3 / 1alpha,25-dihydroxy-24a,24b-dihomo-23-oxacholecalciferol


(20S,23)-dihydroxyvitamin D3

A hydroxycalciol that consists of vitamin D3 (calciol) carrying additional hydroxy groups  at positions 20 (with S-configuration) and 23.


name: (25R)-26,26,26-trifluoro-1alpha,25-dihydroxyvitamin D3 / (25R)-26,26,26-trifluoro-1alpha,25-dihydroxycholecalciferol


name: 1alpha-Hydroxy-25,26,27-trinorvitamin D3 24-carboxylic acid


name: 1alpha,25-dihydroxy-20-epivitamin D2 / 1alpha,25-dihydroxy-20-epiergocalciferol


name: (23Z)-25-hydroxy-16,17,23,24-tetradehydrovitamin D3 / (23Z)-25-hydroxy-16,17,23,24-tetradehydrocholecalciferol


name: (23S,25R)-25-hydroxyvitamin D3 26,23-lactol / (23S,25R)-25-hydroxycholecalciferol 26,23-lactol


vitamin D5

A vitamin D in which the side-chain at position 17 consists of a (5R)-5-ethyl-6-methylheptan-2-yl group.


name: (10e)-19-(3-carboxylpropyl)vitamin d3 / (10e)-19-(3-carboxylpropyl)cholecalciferol


name: (20S)-1alpha,25-dihydroxy-20-methoxyvitamin D3 / (20S)-1alpha,25-dihydroxy-20-methoxycholecalciferol


name: 1alpha,25-dihydroxy-24a,24b-dihomo-22-oxavitamin D3 / 1alpha,25-dihydroxy-24a,24b-dihomo-22-oxacholecalciferol


name: (24R)-1alpha,24,25,26-tetrahydroxyvitamin D2 / (24R)-1alpha,24,25,26-tetrahydroxyergocalciferol


name: (24S,25S)-25,26-epoxy-1alpha,24-dihydroxyvitamin D3 / (24S,25S)-25,26-epoxy-1alpha,24-dihydroxycholecalciferol


name: 23,23-difluoro-1alpha,25-dihydroxyvitamin D3 / 23,23-difluoro-1alpha,25-dihydroxycholecalciferol


name: 1alpha,25-dihydroxy-24a-homo-22-thiavitamin D3 / 1alpha,25-dihydroxy-24a-homo-22-thiacholecalciferol


name: 1alpha,25-Dihydroxyvitamin D3 25-trimethylsilyl ether


name: (24S,25R)-25,26-epoxy-1alpha,24-dihydroxyvitamin D3 / (24S,25R)-25,26-epoxy-1alpha,24-dihydroxycholecalciferol


1alpha,2beta,25-trihydroxy vitamin D3

A hydroxy seco-steroid that is calciol carrying three additional hydroxy substituents at positions 1alpha, 2beta and 25.


A hydroxycalciol that is a synthetic analogue of vitamin D3 which contains an oxolane ring and exhibits weak vitamin D receptor agonist activity


D3 vitamins

A vitamin D that is calciol or its hydroxylated metabolites calcidiol and calcitriol. Calciol (also known as vitamin D3) acts as a hormone precursor, being hydroxylated in the liver to calcidiol (25-hydroxyvitamin D3), which is then further hydroxylated in the kidney to give calcitriol (1,25-dihydroxyvitamin D3), the active hormone.


A hydroxycalciol that is calcitriol with an acetoxy group at C-18.


name: 1alpha,25-dihydroxy-24-nor-22-oxavitamin D3 / 1alpha,25-dihydroxy-24-nor-22-oxacholecalciferol


5,6-trans-vitamin D3

A member of the class of D3 vitamins that is calciol in which the double bond at position 5 adopts a trans-configuration. During exposure to sunlight, previtamin D3 and vitamin D3 in the skin become photoisomerized to 5,6-trans-vitamin D3.


tacalcitol

A hydroxy seco-steroid that is calciol which carries hydroxy groups at positions 1S and 24R. It is a vitamin D3 analog which is used for the treatment of psoriasis vulgaris in adults, especially on the scalp.


(20S,24R)-dihydroxyvitamin D3

A hydroxycalciol that consists of vitamin D3 (calciol) carrying additional hydroxy groups at positions 20 (with S-configuration) and 24 (with R-configuration).


20(S),25-dihydroxyvitamin D3

A hydroxycalciol that consists of vitamin D3 (calciol) carrying additional hydroxy groups  at positions 20 (with S-configuration) and 25.


ERCALCITRIOL

A hydroxycalciol that is vitamin D2 bearing additional hydroxy substituents at positions 1alpha and 25.


name: 26,26,26-trifluoro-25-hydroxyvitamin D3 / 26,26,26-trifluoro-25-hydroxycholecalciferol


calcidiol 25-O-(beta-D-glucuronide)

A steroid glucosiduronic acid that is calcidiol in which the hydroxy hydrogen at position 25 has been replaced by a beta-D-glucuronyl residue.


name: 1alpha,25-dihydroxy-11beta-methoxyvitamin D3 / 1alpha,25-dihydroxy-11beta-methoxycholecalciferol


name: (24R,25R)-25,26-epoxy-1alpha,24-dihydroxyvitamin D3 / (24R,25R)-25,26-epoxy-1alpha,24-dihydroxycholecalciferol


ACC/AHA Ischemic ECG Changes

description: An electrocardiographic finding, in the absence of left ventricular hypertrophy (LVH) and left bundle branch block pattern on ECG, of either a) new (or presumed new) ST elevation at the J point in two contiguous leads with the following cut-points: greater than or equal to 0.1 mV in all leads other than leads V2-V3 where the following cut points apply: greater than or equal to 0.2 mV in men age greater than or equal to 40 years, greater than or equal to 0.25 mV in men age greater than 40 years, or greater than or equal to 0.15 mV in women; or b) new (or presumed new) horizontal or down-sloping ST depression greater than or equal to 0.05 mV in two contiguous leads, and/or T wave inversion greater than or equal to 0.1 mV in two contiguous leads with a prominent R wave, or R/S ratio greater than 1. (Thygesen K, Alpert JS, Jaffe AS, et al.: the Writing Group on behalf of the Joint ESC/ACCF/AHA/WHF Task Force for the Universal Definition of Myocardial Infarction. J Am Coll Cardiol 60(16):1-18, 2012)


A polyprenylhydroquinone in which the polyprenyl substituent is decaprenyl at C-2; additional methyl and methoxy groups are also present at positions C-3 and C-6 respectively.


His-Val

A dipeptide formed from L-histidine and L-valine residues.


Grade 2 Jejunal Obstruction, CTCAE

description: Symptomatic; altered GI function; limiting instrumental ADL


name: Grade 2 Head Soft Tissue Necrosis, CTCAE

description: Local wound care; medical intervention indicated (e.g., dressings or topical medications)


A 6-alkyl-4-hydroxy-2H-pyran-2-one that is 4-hydroxy-2H-pyran-2-one in which the hydrogen at position 6 is replaced by an 11-methyldodecyl group.


Any member of the class of 2-pyranones that is 4-hydroxy-2H-pyran-2-one in which the hydrogen at position 6 has been replaced by an alkyl group.


A 6-alkyl-4-hydroxy-2H-pyran-2-one that is 4-hydroxy-2H-pyran-2-one in which the hydrogen at position 6 is replaced by an 11-hydroxyheptadecyl group.


A 6-alkyl-4-hydroxy-2H-pyran-2-one that is 4-hydroxy-2H-pyran-2-one in which the hydrogen at position 6 is replaced by a 2-methyldecyl group.


A 6-alkyl-4-hydroxy-2H-pyran-2-one that is 4-hydroxy-2H-pyran-2-one in which the hydrogen at position 6 is replaced by a 2-hydroxytridecyl group.


A 6-alkyl-4-hydroxy-2H-pyran-2-one that is 4-hydroxy-2H-pyran-2-one in which the hydrogen at position 6 is replaced by a 15-hydroxypentadecyl group.


A 6-alkyl-4-hydroxy-2H-pyran-2-one that is 4-hydroxy-2H-pyran-2-one in which the hydrogen at position 6 is replaced by a non-8-en-1-yl group.


A 6-alkyl-4-hydroxy-2H-pyran-2-one that is 4-hydroxy-2H-pyran-2-one in which the hydrogen at position 6 is replaced by a hexadecan-2-yl group.


A 6-alkyl-4-hydroxy-2H-pyran-2-one that is 4-hydroxy-2H-pyran-2-one in which the hydrogen at position 6 is replaced by a 14-hydroxytetradecyl group.


A 6-alkyl-4-hydroxy-2H-pyran-2-one that is 4-hydroxy-2H-pyran-2-one in which the hydrogen at position 6 is replaced by an 11-methylheptadecyl group.


Splenic Plasmacytoma

description: A plasmacytoma that arises in the spleen.


name: Splenic B-Cell Lymphoma/Leukemia, Unclassifiable

description: A small B-cell clonal lymphoproliferative disorder of the spleen that does not fall into any of the other categories of mature B-cell neoplasms.


Malignant Splenic Soft Tissue Neoplasm

description: A malignant mesenchymal neoplasm that arises from the spleen.


Recurrent Hairy Cell Leukemia Variant

description: The reemergence of hairy cell leukemia variant after a period of remission.


name: Splenic Manifestation of Chronic Myeloid Leukemia, BCR-ABL1 Positive

description: Infiltration and expansion of the red pulp and sinusoids of the spleen by chronic myeloid leukemia, BCR-ABL1 positive.


name: Splenic Manifestation of B-Cell Prolymphocytic Leukemia

description: Infiltration and expansion of the white and red pulp of the spleen by B-cell prolymphocytic leukemia.


name: Extramedullary Disease in Multiple Myeloma Involving the Spleen

description: Infiltration of the spleen by malignant (clonal) plasma cells in patients with history of multiple myeloma


name: Sclerosing angiomatoid nodular transformation of spleen

description: A benign, circumscribed lesion that arises from the spleen and is composed of multiple angiomatoid nodules in a fibrosclerotic stroma. It most often affects middle-aged females. It is usually asymptomatic, and most cases are detected incidentally on imaging studies.


name: Splenic Manifestation of T-Cell Prolymphocytic Leukemia

description: Infiltration and expansion of the white and red pulp of the spleen by T-cell prolymphocytic leukemia.


Malignant lymphoma of spleen

description: A non-Hodgkin lymphoma or rarely Hodgkin lymphoma that arises from the spleen.


name: Splenic Manifestation of T-Cell Large Granular Lymphocyte Leukemia

description: Infiltration and expansion of the red pulp cords and sinusoids of the spleen by T-cell large granular lymphocyte leukemia. The white pulp of the spleen is not involved and is often hyperplastic.


thiacloprid-amide

A monochloropyridine that is 2-chloropyridine substituted by a [2-(carbamoylimino)-1,3-thiazolidin-3-yl]methyl group at position 5. It is a metabolite of the insecticide thiacloprid.


A member of the class of thiazolidinones that is 3-[(dimethylamino)methyl]-1,3-thiazolidine-2,4-dione bearing an additional (4-methoxyphenyl)methylidene substituent at position 5.


name: 3-[4-oxo-5-(phenylmethylene)-2-sulfanylidene-3-thiazolidinyl]propanoic acid butyl ester


A thiazolidinone that is 1,2-thiazolidin-3-one bearing an amino substituent at position 4.


optovin

A member of the class of thiazolidinone that is rhodanine in which the two methylene hydrogens have been replaced by a 2,5-dimethyl-1-(pyridin-3-yl)-1H-pyrrol-3-yl]methylidene group. A TRPA1 ligand that can be reversibly photoactivated.


pyochelin

A member of the class of thiazolidines that is (4R)-3-methyl-1,3-thiazolidine-4-carboxylic acid which is substituted at position 2 by a (4R)-2-(2-hydroxyphenyl)-4,5-dihydro-1,3-thiazol-4-yl group. A siderophore that is produced by Pseudomonas aeruginosa (via condensation of salicylic acid and two molecules of cysteine) as a mixture of two easily interconvertible diastereoisomers, pyochelin I (major) and pyochelin II (minor). The enantiomeric compounds, enant-pyochelin, are produced by Pseudomonas fluorescens.


A thiazolidinone that is 2-thioxo-4-thiazolidinone which is substituted at position 3 by a (m--trifluoromethyl)phenyl group and at position 5 by a p-carboxybenzylidene group. It is an inhibitor of cystic fibrosis transmembrane conductance regulator, a membrane protein and chloride channel in vertebrates that is encoded by the CFTR gene.


A member of the class of oxindoles that is 5-chloro-oxindole in which the methylene hydrogens at position 3 have been replaced by an N-(2-carboxyethyl)rhodanin-5-ylidene group.


YERSINIABACTIN

A member of the class of thiazolidines that is (4S)-4-methyl-4,5-dihydro-1,3-thiazole-4-carboxylic acid which is substituted at position 2 by a (1S)-1-hydroxy-1-{(4R)-2-[(4R)-2-(2-hydroxyphenyl)-4,5-dihydro-1,3-thiazol-4-yl]-1,3-thiazolidin-4-yl}-2-methylpropan-2-yl group. A siderophore found in the gram-negative bacterium species, Yersinia enterocolitica and Yersinia pestis.


flutianil

A member of the class of thiazolidines that is N-(o-methoxyphenyl)thiazolidine which is substituted at position 2 by a methylene group, the hydrogens of which are replaced by cyano and [2-fluoro-5-(trifluoromethyl)phenyl]sulfanediyl groups; the double bond conjugated to the cyano group has Z configuration. A fungicide intended for use on horticultural crops including strawberries and grapevines.


A member of the class of thiazolidinones that is 2-sulfanylidene-1,3-thiazolidin-4-one in which the hydrogens at positions 3 and 5 are replaced by carboxymethyl and 3-(1-phenylethoxy)-4-(2-phenylethoxy)benzylidene groups, respectively. It is an inhibitor of protein mannosyl transferase 1 (PMT1) and blocks protein O-mannosylation.


A thiazolidinone that is the 5-{[4-(pyridin-4-yl)quinolin-6-yl]methylene} derivative of 1,3-thiazolidine-2,4-dione. A PI3K inhibitor


pyochelin II

A pyochelin that has S-stereochemistry at the thioaminal centre; the diastereoisomer with R-stereochemistry at this centre is pyochelin I. Pseudomonas aeruginosa produces a mixture of pyochelin I (major) and pyochelin I (minor) via condensation of salicylic acid and two molecules of cysteine. The enantiomeric compounds, enant-pyochelin I and II, are produced by Pseudomonas fluorescens.


1,3-Thiazolidine substituted with methyl groups at C-2, -5 and -5 and with a carboxy group at C-4, representing the thiazolidine ring of a generalised penicillin structure.


LERIGLITAZONE

A member of the class of thiazolidenediones that is the hydroxy derivative of pioglitazone.


A trimethyl-substituted thiazolidine carboxylic acid derived by cleavage of and loss of C=O from the azetidine ring of penicillanic acid.


A  thiazolidinecarboxamide that is 1,3-thiazolidine-2-carboxamide substituted by a methyl group at position 2.


pyochelin I

A pyochelin that has R-stereochemistry at the thioaminal centre; the diastereoisomer with S-stereochemistry at this centre is pyochelin II. Pseudomonas aeruginosa produces a mixture of pyochelin I (major) and pyochelin II (minor) via condensation of salicylic acid and two molecules of cysteine. The enantiomeric compounds, enant-pyochelin I and II, are produced by Pseudomonas fluorescens.


LATRUNCULIN B

A macrolide consisting of a 14-membered bicyclic lactone attached to the rare 2-thiazolidinone moiety. It is obtained from the Red Sea sponge Latrunculia magnifica.


lugdunin

A thiazolidine-containing homodetic cyclic peptide that is isolated from human nasal bacteria. Exhibits bactericidal activity against many major pathogens including methicillin-resistant Staphylococcus aureus (MRSA).


thiazolidinediones

A thiadiazolidine in which the 1,3-thiazolidine ring is substituted by two oxo groups.


benzylpenicilloic acid

A penicilloic acid where the side-chain N-acyl group is specified as phenylacetyl.


benzylpenicilloyl-cysteine

A compound obtained from nucleophilic cleavage of the beta-lactam ring of benzylpenicillin by the amino group of L-cysteine.


A thiazolidinone that is 2-sulfanylidene-1,3-thiazolidin-4-one substituted by 3-{[3-(morpholin-4-yl)propyl]amino}-3-oxopropyl and 4-ethylbenzylidene groups at positions 3 and 5, respectively. It is a ferroptosis inducer.


rhodanine 3-acetic acid derivative

Any thiazolidinone that is derived from rhodanine 3-acetic acid.


A member of the class of thiazolidinones that is 2-sulfanylidene-1,3-thiazolidin-4-one which is substituted at position 5 by a (4-ethylphenyl)methylidene group. It is a cell permeable inhibitor of c-Myc-Max dimerization and exhibits antitumour effects in vivo. It downregulates c-Myc expression and upregulates CDK inhibitors, p21 and p27 resulting in the inhibition of proliferation, induction of apoptosis and cell cycle arrest in G0/G1 phase.


thiacloprid

A  nitrile that is cyanamide in which the hydrogens are replaced by a 1,3-thiazolidin-2-ylidene group which in turn is substituted by a (6-chloropyridin-3-yl)methyl group at the ring nitrogen.


penicilloic acid

A thiazolidinedicarboxylic acid obtained via hydrolysis of the beta-lactam ring of a penicillin.


A member of the class of thiazolidinones that is 1,1-dioxo-2,3-diphenyl-1,3-thiazolidin-4-one bearing an additional (4-methoxyphenyl)methylidene substituent at position 5.


Wound Discharge

description: The material exuded from a wound, either surgical or traumatic.


Paratesticular Paraganglioma

description: An extremely rare paraganglioma that arises from the paratesticular structures.


name: Hematologic Neoplasm with Germline Predisposition Associated with a Constitutional Disorder Affecting Multiple Organ Systems

description: Familial hematologic neoplasms associated with germline mutations and a preexisting disorder or organ dysfunction other than a platelet disorder.


name: Hematologic Neoplasm with Germline Predisposition Associated with Inherited Bone Marrow Failure Syndrome

description: Familial myelodysplastic syndromes/ acute myeloid leukemias associated with inherited bone marrow failure syndromes.


name: Hematologic Neoplasm with Germline GATA2 Mutation

description: Myelodysplastic syndromes/acute myeloid leukemias associated with germline GATA2 mutation.


name: Hematologic Neoplasm with Germline SAMD9 Mutation

description: Myelodysplastic syndromes/acute myeloid leukemias associated with germline SAMD9 mutation.


name: Hematologic Neoplasm with Germline SAMD9L Mutation

description: Myelodysplastic syndromes/acute myeloid leukemias associated with germline SAMD9L mutation.


name: Juvenile Myelomonocytic Leukemia Associated with Neurofibromatosis

description: Juvenile myelomonocytic leukemia that is associated with neurofibromatosis type 1 (NF1).


name: Juvenile Myelomonocytic Leukemia Associated with Noonan Syndrome-Like Disorder

description: Juvenile myelomonocytic leukemia that is associated with a genetic disorder caused by germline mutations in the CBL gene and phenotypically resembles Noonan syndrome (Noonan syndrome-like disorder).


name: Hematologic Neoplasm Associated with Down Syndrome

description: Hematologic neoplasms occurring in individuals with Down syndrome.  There is an increased risk of acute leukemias in both children and adults with Down syndrome.  In particular, the incidence of acute myeloid leukemia in Down syndrome children of less than five years of age is particularly high, it is usually an acute megakaryoblastic leukemia, and is associated with GATA1 gene mutation.  This group of disorders also includes the entity transient abnormal myelopoiesis which occurs in neonates and is associated with GATA1 gene mutation.


name: Hematologic Neoplasm with Germline Predisposition Associated with Telomerase Biology Disorder

description: Familial myelodysplastic syndromes/ acute myeloid leukemias associated with telomerase biology disorders.


Serous Tubal Intraepithelial Lesion

description: A non-invasive, precursor epithelial proliferation that arises from the fallopian tube, lacks severe atypia, and demonstrates serous differentiation.


name: 4-[[3-oxo-2-(3-pyridinyl)-1H-isoindol-1-yl]amino]benzoic acid ethyl ester


N-OXALYLGLYCINE

An amino dicarboxylic acid that is iminodiacetic acid with an oxo substituent. It is used as an inhibitor of alpha-ketoglutarate dependent (EC 1.14.11.*) enzymes.


Stress Fractures

description: A small, traumatic break or severe bruising of a bone caused by repetitive application of force.


Fracture of Ulna Related to Birth

description: A broken ulna sustained during the birthing process.


Closed Monteggia's fracture

description: Proximal radial head dislocation in association with a proximal ulnar fracture that does not involve a break in the adjacent skin.


Fracture of Clavicle Related to Birth

description: An injury sustained during the birthing process in which the continuity is broken in the clavicle.


Fracture of acetabulum

description: A traumatic break in the portion of the pelvic bone that forms the hip socket.


Fracture of Femur Related to Birth

description: A broken femur sustained during the birthing process.


Closed fracture of rib

description: A traumatic break in one of the bones in the rib cage that does not involve a break in the adjacent skin.


Fracture of metacarpal bone

description: A traumatic break in one or more of the metacarpal bones.


name: Closed fracture of shaft of metacarpal bone

description: A traumatic break in the diaphysis of the metacarpal bone that does not involve a break in the adjacent skin.


Closed fracture of multiple ribs

description: A traumatic break in two or more places in one rib, or a traumatic break in more than one rib, that does not involve a break in the adjacent skin.


Closed fracture of pelvis

description: A traumatic break in one or more of the bones comprising the bony structure of the pelvis that does not involve a break in the adjacent skin.


Fracture of foot

description: A traumatic break in one or more of the bones in the foot.


Open fracture of rib

description: A traumatic break in one of the bones in the rib cage  that involves a break in the adjacent skin.


Closed fracture of metacarpal bone

description: A traumatic break in one or more of the metacarpal bones that does not involve a break in the adjacent skin.


Fracture of mandible, closed

description: A traumatic break in the mandible  that does not involve a break in the adjacent skin.


name: Closed fracture of malar AND/OR maxillary bones

description: A traumatic break in the malar and maxillary bones  that does not involve a break in the adjacent skin.


Fracture Related to Birth

description: A broken bone sustained during the birthing process.


name: Closed fracture of neck of metacarpal bone

description: A traumatic break in the area of the metacarpal bone located between the diaphysis and the distal metaphysis that does not involve a break in the adjacent skin.


Fracture of bone involving growth plate

description: A traumatic break in a long bone that involves the epiphyseal plate.


Lumbar vertebral fracture L2

description: A traumatic break in the second lumbar spinal vertebra.


Upper Extremity Fracture

description: A traumatic break in one or more of the bones in the arm,  forearm, or hand.


Fracture of clavicle

description: A traumatic or pathologic injury to the clavicle in which the continuity of the clavicle is broken.


Fracture of Humerus Related to Birth

description: A broken humerus sustained during the birthing process.


Fracture of phalanx of finger

description: A traumatic break in one or more of the bones in one of the digits of the hand.


name: Open fracture of neck of metacarpal bone

description: A traumatic break in the area of the metacarpal bone located between the diaphysis and the distal metaphysis that involves a break in the adjacent skin.


Closed Colles' fracture

description: An extra-articular traumatic break in the distal radius with dorsal displacement of the distal fragment that does not involve a break in the adjacent skin.


Fracture of Spine Related to Birth

description: A broken vertebra sustained during the birthing process.


Fracture of Radius Related to Birth

description: A broken radius sustained during the birthing process.


Colles' Fracture

description: An extra-articular traumatic break in the distal radius with dorsal displacement of the distal fragment.


Fracture of wrist

description: Traumatic injury to the wrist joint in which the continuity of a wrist bone is broken. Symptoms include wrist pain, swelling, and deformity of wrist.