Refractory Grade 3a Follicular Lymphoma

description: Grade 3a follicular lymphoma that is resistant to treatment.


name: Refractory Nodular Lymphocyte Predominant B-Cell Lymphoma

category: biolink:Disease biolink:DiseaseOrPhenotypicFeature biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing

description: Nodular lymphocyte predominant B-cell lymphoma that is resistant to treatment.


Primary Iris Non-Hodgkin Lymphoma

description: An extremely rare low-grade B-cell non-Hodgkin lymphoma that arises from the iris. It is characterized by the presence of a diffuse infiltrate of small, round lymphocytes. Most cases represent extranodal marginal zone lymphomas of mucosa-associated lymphoid tissue.


follicular lymphoma of lung

description: An exceedingly rare follicular lymphoma that arises in and is confined to the lung at the time of diagnosis.


breast diffuse large B-cell lymphoma

description: A diffuse large B-cell lymphoma that arises from the breast. It is the most common type of primary breast lymphoma.


name: Lymphoplasmacytic Lymphoma by Ann Arbor Stage

description: An anatomic stage for lymphoplasmacytic lymphoma based on the Ann Arbor classification criteria.


name: Refractory Primary Diffuse Large B-Cell Lymphoma of the Central Nervous System

description: Primary diffuse large B-cell lymphoma of the central nervous system that does not respond to treatment.


name: Lacrimal Drainage System Non-Hodgkin Lymphoma

description: A non-Hodgkin lymphoma that arises from the lacrimal sac. The majority of cases are of B-cell type. The most common subtypes are mucosa-associated lymphoid tissue lymphoma and diffuse large B-cell lymphoma.


name: Diffuse large B-cell lymphoma refractory

description: Diffuse large B-cell lymphoma that is resistant to treatment.


extranodal nasal NK/T cell lymphoma

description: Extranodal nasal NK/T cell lymphoma (NKTCL) is a rare, malignant neoplasm mainly affecting men in the fifth decade of life, that usually arises in the nose, paranasal sinuses, orbits or upper airway, and that can present with a nasal mass, nasal bleeding, nasal obstruction, palate perforation (i.e. midline perforation of the hard palate), and mid-facial and/or upper airway destructive lesions. In advanced disease stages, which are associated with a poor prognosis, NKTCL may disseminate to other organs. A few cases of NKTCL presenting primarily in the lymph nodes have also been described.


indolent B-cell non-Hodgkin lymphoma

description: A B-cell non-Hodgkin lymphoma with an indolent clinical course. Representative examples include grade 1 and grade 2 follicular lymphoma, marginal zone lymphoma, and lymphoplasmacytic lymphoma.


name: Recurrent HHV8-Positive Diffuse Large B-Cell Lymphoma, Not Otherwise Specified

description: The reemergence of HHV8-positive diffuse large B-cell lymphoma, not otherwise specified, after a period of remission.


Mycosis Fungoides by AJCC v7 Stage

description: A term that refers to the staging of mycosis fungoides, following the rules of the TNM AJCC v7 classification system.


name: Cardiac Fibrin-Associated Diffuse Large B-Cell Lymphoma

description: A rare fibrin-associated diffuse large B-cell lymphoma that affects the heart.


name: Childhood Nodular Lymphocyte Predominant Hodgkin Lymphoma

description: A nodular lymphocyte predominant B-cell lymphoma occurring in children.


Recurrent Grade 3 Follicular Lymphoma

description: The reemergence of grade 3 follicular lymphoma after a period of remission.


name: Central Nervous System Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma

description: A primary central nervous system non-Hodgkin lymphoma derived from mature or post-thymic T-cells or NK-cells.


name: Recurrent Primary Cutaneous Gamma-Delta T-Cell Lymphoma

description: The reemergence of primary cutaneous gamma-delta T-cell lymphoma after a period of remission


name: Transformed Waldenstrom Macroglobulinemia to Diffuse Large B-Cell Lymphoma

description: Histologic transformation of Waldenstrom macroglobulinemia to an aggressive diffuse large B-cell lymphoma.


name: diffuse large B-cell lymphoma germinal center B-cell type

description: A diffuse large B-cell lymphoma that is characterized by the expression of CD10, BCL-6, A-myb, and LMO2 genes, BCL-2 translocation, and c-REL amplification.


name: Ann Arbor Stage I Mature T- and NK-Cell Lymphoma

description: Ann Arbor Classification: Stage I: Involvement of a single lymph node region (I); or localized involvement of a single extralymphatic organ or site in the absence of any lymph node involvement (IE).


name: Extranodal Marginal Zone Lymphoma of Mucosa-Associated Lymphoid Tissue by Ann Arbor Stage

description: An anatomic stage for extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue based on the Ann Arbor classification criteria.


AIDS-Related Primary Effusion Lymphoma

description: Primary effusion lymphoma occurring in HIV-positive patients.


Conjunctival Follicular Lymphoma

description: A follicular lymphoma that arises from the conjunctiva.


Lymphoepithelioid lymphoma

description: A variant of peripheral T-cell lymphoma, not otherwise specified. It is characterized by the presence of neoplastic small lymphocytes infiltrating the lymph nodes in a diffuse and less frequently interfollicular pattern. There is an associated proliferation of epithelioid histiocytes forming confluent clusters.


Stage IV Childhood Non-Hodgkin Lymphoma

description: Ann Arbor Classification: Stage IV: Diffuse or disseminated involvement of one or more extralymphatic organs, with or without associated lymph node involvement; or isolated extralymphatic organ involvement in the absence of adjacent regional lymph node involvement, but in conjunction with disease in distant site(s); or any involvement of the liver or bone marrow, lungs (other than by direct extension from another site), or cerebrospinal fluid.


name: Lugano Classification Stage IIE Adult Non-Hodgkin Lymphoma AJCC v8

description: Stage IIE: Contiguous extralymphatic extension from a nodal site with or without involvement of other lymph node regions on the same side of the diaphragm. (from AJCC 8th Ed.)


Sezary syndrome recurrent

description: The reemergence of Sezary syndrome after a period of remission.


name: St. Jude Stage I Childhood Non-Hodgkin Lymphoma AJCC v8

description: Stage I: A single tumor (extranodal) or single anatomic area (nodal), with the exclusion of the mediastinum or abdomen. (from AJCC 8th Ed.)


Advanced Anaplastic Large Cell Lymphoma

description: Anaplastic large cell lymphoma that has spread extensively to distant anatomic sites.


name: Refractory Indolent B-Cell Non-Hodgkin Lymphoma

description: Indolent B-cell non-Hodgkin lymphoma that is resistant to treatment.


name: AIDS-Related Diffuse Large B-cell Lymphoma

description: A diffuse large B-cell lymphoma occurring in HIV-positive patients.


name: Refractory Primary Cutaneous Gamma-Delta T-Cell Lymphoma

description: Primary cutaneous gamma-delta T-cell lymphoma that is resistant to treatment.


name: Primary mediastinal large B-cell lymphoma stage II

description: Ann Arbor Classification: Stage II: Involvement of two or more lymph node regions on the same side of the diaphragm (II); or localized involvement of a single extralymphatic organ or site in association with regional lymph node involvement with or without involvement of other lymph node regions on the same side of the diaphragm (IIE).


name: Central Nervous System T-Cell Non-Hodgkin Lymphoma

description: A T-cell lymphoblastic lymphoma or a mature T-cell and NK-cell neoplasm that affects the brain, meninges, or spinal cord.


anaplastic large cell lymphoma of lung

description: A rare anaplastic large cell lymphoma that arises in the lung parenchyma.


Colorectal Mantle Cell Lymphoma

description: A mantle cell lymphoma that arises from the colon or rectum.  It often presents as a polypoid lesion.


name: Refractory Subcutaneous Panniculitis-Like T-Cell Lymphoma

description: Subcutaneous panniculitis-like T-cell lymphoma that is resistant to treatment.


name: Recurrent Aggressive Adult Non-Hodgkin Lymphoma

description: The reemergence of an aggressive adult non-Hodgkin lymphoma after a period of remission.


follicular lymphoma of thyroid gland

description: A rare follicular lymphoma primarily involving the thyroid gland.


name: Ann Arbor Stage II Supradiaphragmatic Nodular Lymphocyte Predominant B-Cell Lymphoma


name: B-cell small lymphocytic lymphoma stage III

description: Ann Arbor Classification: Stage III: Involvement of lymph node regions on both sides of the diaphragm (III), which also may be accompanied by extralymphatic extension in association with adjacent lymph node involvement (IIIE) or by involvement of the spleen (IIIS) or both (IIIE,S).


name: primary cutaneous follicle center lymphoma

description: A primary lymphoma of the skin composed of various numbers of small and large irregular neoplastic follicle center cells. Its morphologic pattern can be nodular, diffuse, or nodular and diffuse. It presents with solitary or grouped plaques and tumors, and it usually involves the scalp, forehead, or trunk. It rarely involves the legs. This type of cutaneous lymphoma tends to remain localized to the skin.


name: Conjunctival Mucosa-Associated Lymphoid Tissue Lymphoma

description: A mucosa-associated lymphoid tissue lymphoma affecting the conjunctiva.


Indolent Adult Non-Hodgkin Lymphoma

description: An indolent non-Hodgkin lymphoma occurring in adults.  Representative examples include small lymphocytic lymphoma, lymphoplasmacytic lymphoma/Waldenstrom's macroglobulinemia, marginal zone B-cell lymphoma, and grade 1 and 2 follicular lymphoma.


name: Small Lymphocytic Lymphoma with Unmutated Immunoglobulin Heavy Chain Variable-Region Gene

description: Small lymphocytic lymphoma characterized by the absence of somatic hypermutation within the immunoglobulin heavy chain gene variable region of neoplastic clones. Patients have a significantly worse prognosis as compared to those with mutated immunoglobulin heavy chain gene variable region rearrangements.


splenic diffuse large B-cell lymphoma

description: A diffuse large B-cell lymphoma occurring in the spleen.


name: Noncutaneous Anaplastic Large Cell Lymphoma by Ann Arbor Stage

description: An anatomic stage for noncutaneous anaplastic large cell lymphoma based on the Ann Arbor classification criteria.


name: Refractory Systemic Anaplastic Large Cell Lymphoma, ALK-Positive

description: Systemic anaplastic large cell lymphoma, ALK-positive that is resistant to treatment.


name: Stage IIIA Mycosis Fungoides and Sezary Syndrome AJCC v8

description: Stage IIIA includes: T4, N0-2, M0, B0. T4: Confluence of erythema covering 80% or more of body surface area. N0: No clinically abnormal peripheral lymph nodes; biopsy not required. N1: Clinically abnormal peripheral lymph nodes; histopathology Dutch grade 1 or National Cancer Institute (NCI) LN0-2. N2: Clinically abnormal peripheral lymph nodes; histopathology Dutch grade 2 or NCI LN3. M0: No visceral organ involvement. B0: Absence of significant blood involvement: 5% or less of peripheral blood lymphocytes are atypical (Sezary cells). (AJCC 8th ed.)


name: Adult Non-Hodgkin Lymphoma by Ann Arbor Stage

description: An anatomic stage for adult non-Hodgkin lymphoma based on the Ann Arbor classification criteria.


Adult B Lymphoblastic Lymphoma

description: B-lymphoblastic lymphoma that occurs in adults.


name: Nasal Type NK/T-Cell Lymphoma by Ann Arbor Stage

description: An anatomic stage for nasal type NK/T-cell lymphoma based on the Ann Arbor classification criteria.


name: Primary Cutaneous T-Cell/Histiocyte-Rich Large B-Cell Lymphoma

description: T-Cell/histiocyte-rich large B-cell lymphoma that arises from the skin.


Intestinal T-cell lymphoma stage IV

description: Ann Arbor Classification: Stage IV: Diffuse or disseminated involvement of one or more extralymphatic organs, with or without associated lymph node involvement; or isolated extralymphatic organ involvement in the absence of adjacent regional lymph node involvement, but in conjunction with disease in distant site(s); or any involvement of the liver or bone marrow, lungs (other than by direct extension from another site), or cerebrospinal fluid.


Stage I Childhood Burkitt Lymphoma

description: Ann Arbor Classification: Stage I: Involvement of a single lymph node region (I); or localized involvement of a single extralymphatic organ or site in the absence of any lymph node involvement (IE).


Peripheral T-Cell Lymphoma-GATA3

description: A molecular subtype of peripheral T-cell lymphoma, not otherwise specified, characterized by high expression of GATA3. It is composed of a monomorphic lymphocytic infiltrate with minimal inflammation and is associated with a poor prognosis.


name: Recurrent Nodular Lymphocyte Predominant B-Cell Lymphoma

description: The reemergence of nodular lymphocyte predominant B-cell lymphoma after a period of remission.


name: Small Intestinal B-Cell Non-Hodgkin Lymphoma

description: A B-cell non-Hodgkin lymphoma that arises from the small intestine.  Representative examples include diffuse large B-cell lymphoma, mucosa-associated lymphoid tissue lymphoma, alpha heavy chain disease/immunoproliferative small intestinal disease, Burkitt lymphoma, follicular lymphoma, and mantle cell lymphoma.


name: Childhood Primary Mediastinal Large B-Cell Lymphoma

description: Primary mediastinal large B-cell lymphoma that occurs during childhood.


Mediastinal T Lymphoblastic Lymphoma

description: A precursor T-lymphoblastic lymphoma that arises from the mediastinum.  It usually presents with an anterior mediastinal mass and respiratory distress.  It may present acutely with superior vena cava syndrome.  It usually affects adolescent and young adult males.  It is treated with aggressive chemotherapy and radiation.  The prognosis is better in the pediatric patients.


name: Refractory Primary Cutaneous T-Cell Non-Hodgkin Lymphoma

description: A T-cell non-Hodgkin lymphoma that arises from the skin and does not respond to treatment.


Indolent Non-Hodgkin Lymphoma

description: A non-Hodgkin lymphoma with an indolent clinical course.


name: breast mucosa-associated lymphoid tissue lymphoma

description: An extranodal marginal zone B-cell lymphoma of mucosa associated lymphoid tissue that arises from the breast as a primary tumor.


name: St. Jude Stage III Childhood Non-Hodgkin Lymphoma AJCC v8

description: Stage III: Two single tumors (extranodal) on opposite sides of the diaphragm. Two or more nodal areas above and below the diaphragm. All the primary intrathoracic tumors (mediastinal, pleural, and thymic). All extensive primary intra-abdominal disease. All paraspinal or epidural tumors, regardless of other tumor site(s). (from AJCC 8th Ed.)


name: Ann Arbor Stage II Aggressive Adult Non-Hodgkin Lymphoma

description: Stage II: Involvement of two or more lymph node regions on the same side of the diaphragm (II) or localized involvement of a single associated extralymphatic organ or site and its regional lymph nodes with or without other lymph node regions on the same side of the diaphragm (IIE). Note: The number of lymph node regions involved may be indicated by a subscript (e.g., II3). (from PDQ)


Double-Expressor Lymphoma

description: A diffuse large B-cell lymphoma characterized by double expression of MYC and BCL2 proteins without MYC and BCL2 gene aberrations. These lymphomas may have a worse prognosis than other diffuse large B-cell lymphomas, not otherwise specified, but they are not as aggressive as the high-grade B-cell lymphomas, with rearrangements of MYC and BCL2 and/or BCL6 genes.


name: Peripheral T-cell lymphoma unspecified refractory

description: Peripheral T-cell lymphoma, not otherwise specified that is resistant to treatment.


plasmablastic lymphoma

description: An aggressive diffuse large B-cell lymphoma frequently arising in the setting of HIV infection and characterized by the presence of large neoplastic cells resembling B-immunoblasts which have the immunophenotypic profile of plasma cells. Sites of involvement include the oral cavity, sinonasal cavity, skin, soft tissues, gastrointestinal tract, and bone.


Recurrent Adult Non-Hodgkin Lymphoma

description: The reemergence of non-Hodgkin lymphoma in adults after a period of remission.


B-cell non-Hodgkin lymphoma

description: The most common type of non-Hodgkin lymphoma. It includes the most frequently seen morphologic variants which are: diffuse large B-cell lymphoma, follicular lymphoma, small lymphocytic lymphoma and marginal zone B-cell lymphoma. -- 2003


splenic marginal zone lymphoma

description: Splenic marginal zone lymphoma is a rare, indolent B-cell non-Hodgkin lymphoma characterized by abnormal clonal proliferation of mature B-lymphocytes with involvement in the spleen, bone marrow and, frequently, the blood. It usually presents with splenomegaly, lymphocytosis, anemia and/or thrombocytopenia. Hepatitis C virus and autoimmune manifestations, such as autoimmune hemolytic anemia and autoimmune thrombocytopenia, could be associated.


Adult T Lymphoblastic Lymphoma

description: T-lymphoblastic lymphoma occurring in adults.


name: primary cutaneous anaplastic large cell lymphoma

description: Primary cutaneous anaplastic large cell lymphoma (C-ALCL) is a rare T-cell non-Hodgkin lymphoma that affects the skin and generally shows no extracutaneous involvement at presentation. It belongs to the spectrum of primary cutaneous CD30+ lymphoproliferative disorders along with lymphomatoid papulosis with which it shares overlapping clinical and histopathologic features.


African Burkitt's lymphoma

description: A clinical variant of Burkitt lymphoma that occurs in equatorial Africa.  The Epstein-Barr virus has been detected in all patients.  It is the most common malignancy of childhood in this area.


description: The reemergence of Waldenstrom macroglobulinemia after a period of remission.


description: T-cell/histiocyte rich large B cell lymphoma (THRLBCL) is a rare variant of diffuse large B-cell lymphoma (DLBCL), mainly affecting middle-aged men and often not being discovered until an advanced disease stage, with involvement of the spleen, liver and bone marrow occurring at a greater frequency than in DLBCL. It is often difficult to diagnose due to its similarity with other lymphoid diseases such as classic Hodgkin lymphoma and nodular lymphocyte-predominant Hodgkin lymphoma and has an aggressive clinical course.


name: Ann Arbor Stage I Nodular Lymphocyte Predominant B-Cell Lymphoma

description: Ann Arbor Classification: Stage I: Involvement of a single lymph node region (I); or localized involvement of a single extralymphatic organ or site in the absence of any lymph node involvement (IE) (rare in Hodgkin lymphoma).


name: Ann Arbor Stage IIX (Bulky) Non-Hodgkin Lymphoma

description: Ann Arbor Stage II non-Hodgkin lymphoma with a mass of nodes with one diameter more than 10cm or a mediastinal mass larger than one third of the transthoracic width. (Cotswolds modification)


name: Refractory Aggressive T-Cell Non-Hodgkin Lymphoma

description: An aggressive T-cell non-Hodgkin lymphoma that is resistant to treatment.


name: Adult T-cell lymphoma/leukemia stage III

description: Ann Arbor Classification: Stage III: Involvement of lymph node regions on both sides of the diaphragm (III), which also may be accompanied by extralymphatic extension in association with adjacent lymph node involvement (IIIE) or by involvement of the spleen (IIIS) or both (IIIE,S).


name: Recurrent Childhood Lymphoblastic Lymphoma

description: The reemergence of lymphoblastic lymphoma in childhood after a period of remission.


name: Burkitt-Like Lymphoma Post-Transplant Lymphoproliferative Disorder

description: A Burkitt-like lymphoma that arises in a patient with a history of organ transplantation.


name: Refractory Follicular Helper T-Cell Lymphoma

description: Follicular helper T-cell lymphoma that is resistant to treatment.


name: high-grade B-cell lymphoma double-hit/triple-hit

description: A B-cell lymphoma that is characterized by the abnormal rearrangement of two genes, MYC gene and either BCL2 or BCL6 genes.


Stage I Adult Non-Hodgkin Lymphoma

description: Ann Arbor Classification: Stage I: Involvement of a single lymph node region (I); or localized involvement of a single extralymphatic organ or site in the absence of any lymph node involvement (IE).


Splenic T Lymphoblastic Lymphoma

description: T-lymphoblastic lymphoma that affects the spleen.


name: Mycosis fungoides/Sezary syndrome stage II

description: Stage II includes: IIA (T1-2, N1-2, M0, B0-1); IIB (T3, N0-2, M0, B0-1). T1: Limited patches, papules, and/or plaques covering less than 10% of the skin surface.  May further stratify into T1a (patch only) vs. T1b (plaque +/- patch).  T2: Patches, papules, or plaques covering 10% or more of the skin surface.  May further stratify into T2a (patch only) vs. T2b (plaque +/- patch).  T3: One or more tumors (equal or greater than 1 cm diameter).  N0: No clinically abnormal peripheral lymph nodes; biopsy not required.  N1: Clinically abnormal peripheral lymph nodes; histopathology Dutch grade 1 or NCI LN0-2.  N2: Clinically abnormal peripheral lymph nodes; histopathology Dutch grade 2 or NCI LN3.  M0: No visceral organ involvement.  B0: Absence of significant blood involvement: 5% or less of peripheral blood lymphocytes are atypical (Sezary cells).  B1: Low blood tumor burden: more than 5% of peripheral blood lymphocytes are atypical (Sezary cells) but does not meet the criteria of B2.  (AJCC 7th ed.)


name: Angioimmunoblastic T-cell lymphoma stage III


Small Intestinal Follicular Lymphoma

description: A follicular lymphoma that arises from the small intestine.  It most often affects the duodenum.


name: Childhood Non-Hodgkin Lymphoma by Toronto Guidelines v2 Stage

description: A term that refers to the staging of childhood non-Hodgkin lymphoma according to the Toronto childhood cancer staging guidelines v2.


name: Nodular Lymphocyte Predominant B-Cell Lymphoma by Ann Arbor Stage

description: An anatomic stage for nodular lymphocyte predominant B-cell lymphoma based on the Ann Arbor classification criteria.


Breast T-Cell Non-Hodgkin Lymphoma

description: A T-cell non-Hodgkin lymphoma that arises from the breast as a primary tumor.  Primary T-cell non-Hodgkin lymphomas of the breast are rare.


Stage IB Mycosis Fungoides AJCC v7

description: Stage IB includes: T2, N0, M0, B0-1. T2: Patches, papules, or plaques covering 10% or more of the skin surface.  May further stratify into T2a (patch only) vs. T2b (plaque +/- patch).  N0: No clinically abnormal peripheral lymph nodes; biopsy not required.  M0: No visceral organ involvement.  B0: Absence of significant blood involvement: 5% or less of peripheral blood lymphocytes are atypical (Sezary cells).  B1: Low blood tumor burden: more than 5% of peripheral blood lymphocytes are atypical (Sezary cells) but does not meet the criteria of B2.  (AJCC 7th ed.)


Head and Neck Mantle Cell Lymphoma

description: A mantle cell lymphoma that affects the head and neck region. The most common site of involvement is the Waldeyer ring, usually the tonsils. Other sites of involvement include the orbit, salivary glands, and nasopharynx.


Acute Adult T-Cell Leukemia/Lymphoma

description: The most common variant of adult T-cell leukemia/lymphoma.  It is characterized by systemic disease with a leukemic phase, generalized lymphadenopathy, and skin lesions.  Hypercalcemia is commonly seen.


name: Ann Arbor Stage II Adult Contiguous Immunoblastic Lymphoma

description: Stage II: Involvement of two or more lymph node regions on the same side of the diaphragm (II) or localized involvement of a single associated extralymphatic organ or site and its regional lymph nodes with or without other lymph node regions on the same side of the diaphragm (IIE). Note: The number of lymph node regions involved may be indicated by a subscript (e.g., II3). (from PDQ)


name: Refractory Diffuse Large B-Cell Lymphoma Activated B-Cell Type

description: Diffuse large B-cell lymphoma activated B-cell type that is resistant to treatment.


Angiocentric lymphoma stage II

description: Ann Arbor Classification: Stage II: Involvement of two or more lymph node regions on the same side of the diaphragm (II); or localized involvement of a single extralymphatic organ or site in association with regional lymph node involvement with or without involvement of other lymph node regions on the same side of the diaphragm (IIE).


Recurrent Gray-Zone Lymphoma

description: The reemergence of gray-zone lymphoma after a period of remission.


name: Recurrent Diffuse Large B-Cell Lymphoma Activated B-Cell Type

description: The reemergence of diffuse large B-cell lymphoma activated B-cell type after a period of remission.


name: adult nodular lymphocyte predominant Hodgkin lymphoma

description: A nodular lymphocyte predominant Hodgkin lymphoma occurring in adults.


name: Lacrimal Drainage System Mucosa-Associated Lymphoid Tissue Lymphoma

description: A mucosa-associated lymphoid tissue lymphoma that arises from the lacrimal sac.


Non-Hodgkin Breast Lymphoma

description: A non-Hodgkin lymphoma that arises from the breast.  There is no history of extramammary breast non-Hodgkin lymphoma and ipsilateral axillary lymph node involvement does not exclude the diagnosis of primary breast non-Hodgkin lymphoma.  Most patients present with a painless breast lump.  The vast majority of cases are B-cell non-Hodgkin lymphomas.  Diffuse large B-cell lymphoma, follicular lymphoma, and extranodal marginal zone B-cell lymphoma of mucosa associated lymphoid tissue are the most common types of primary non-Hodgkin lymphoma of the breast.


name: Common Variant Anaplastic Large Cell Lymphoma

description: An anaplastic large cell lymphoma, characterized by CD30 positive lymphoid cells.


Parotid Gland Non-Hodgkin Lymphoma

description: A non-Hodgkin lymphoma that arises from the parotid gland.  Representative examples include mucosa-associated lymphoid tissue lymphoma and diffuse large B-cell lymphoma.


description: Waldenstrom macroglobulinemia with serum IgM monoclonal protein equal or more than 3 g/dL and/or at least 10% bone marrow lymphoplasmacytic infiltration but no evidence of constitutional symptoms, symptomatic anemia, or hyperviscosity. (Blood 2008, 112:2709)


lymphoblastic lymphoma

description: A lymphoma composed of immature small to medium-sized precursor lymphoid cells (lymphoblasts). It includes the B- and T-cell lymphoblastic lymphoma.


name: Adult EBV-Positive Diffuse Large B-Cell Lymphoma, Not Otherwise Specified

description: An EBV-positive diffuse large B-cell lymphoma, not otherwise specified, that occurs in adults. It was originally described in patients older than 50 years, but it has been increasingly recognized in younger patients.


High grade B-cell lymphoma recurrent

description: The reemergence of high-grade B-cell lymphoma after a period of remission.


BN2 diffuse large B-cell lymphoma

description: A diffuse large B-cell lymphoma that is categorized as BN2 with high probability by the LymphGen algorithm. This is based on a combination of genetic features and BN2 DLBCLs often, but do not always, have a translocation involving the BCL6 locus and/or some combination of mutations affecting NOTCH2, TNFAIP3, BCL10 and UBE2A. This subgroup also commonly has mutations due to aberrant somatic hypermutation affecting CD70, which can be coding or non-coding.


Follicular Lymphoma by Ann Arbor Stage

description: An anatomic stage for follicular lymphoma based on the Ann Arbor classification criteria.


Stage III Non-Hodgkin Lymphoma

description: Ann Arbor Classification: Stage III: Involvement of lymph node regions on both sides of the diaphragm (III), which also may be accompanied by extralymphatic extension in association with adjacent lymph node involvement (IIIE) or by involvement of the spleen (IIIS) or both (IIIE,S).


name: Extranodal marginal zone B-cell lymphoma (MALT type) stage II

description: Extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue presenting as stage II disease.


name: Extranodal marginal zone B-cell lymphoma (MALT type) refractory

description: Extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue that is resistant to treatment.


EBV-Related Burkitt Lymphoma

description: Burkitt lymphoma that is caused by Epstein-Barr virus infection.


name: Refractory Transformed Non-Hodgkin Lymphoma

description: An indolent non-Hodgkin lymphoma which has undergone histologic transformation to an aggressive non-Hodgkin lymphoma and has become resistant to treatment.


Follicular lymphoma stage II

description: Ann Arbor Classification: Stage II: Involvement of two or more lymph node regions on the same side of the diaphragm (II); or localized involvement of a single extralymphatic organ or site in association with regional lymph node involvement with or without involvement of other lymph node regions on the same side of the diaphragm (IIE).


name: Diffuse Large B-Cell Lymphoma by Ann Arbor Stage

description: An anatomic stage for diffuse large B-cell lymphoma based on the Ann Arbor classification criteria.


name: Stage I Childhood Non-Hodgkin Lymphoma by Toronto Guidelines v2

description: Involvement of a single tumor mass or nodal area, excluding the abdomen and mediastinum. (Childhood cancer staging for population registries according to the Toronto Childhood Cancer Stage Guidelines - Version 2. Cancer Council Queensland and Cancer Australia: Brisbane, Australia; 2021.)


name: Ann Arbor Stage I Supradiaphragmatic Nodular Lymphocyte Predominant B-Cell Lymphoma


name: Burkitt Lymphoma Post-Transplant Lymphoproliferative Disorder

description: A Burkitt lymphoma that arises in a patient with a history of organ transplantation.


name: Angioimmunoblastic T-cell lymphoma stage II


folliculotropic mycosis fungoides

description: Folliculotropic mycosis fungoides is a rare variant of mycosis fungoides (MF), a form of cutaneous T-cell lymphoma, and is characterized by the presence of folliculotropic infiltrates in patch-plaque lesions usually involving the head and neck area.


Refractory Plasmablastic Lymphoma

description: Plasmablastic lymphoma that is resistant to treatment.


name: Recurrent Transformed Follicular Lymphoma to Diffuse Large B-Cell Lymphoma

description: The reemergence of transformed follicular lymphoma to diffuse large B-cell lymphoma after a period of remission.


Nasopharyngeal Non-Hodgkin Lymphoma

description: A non-Hodgkin lymphoma that arises from the nasopharynx.


name: Ann Arbor Stage II Contiguous Adult Aggressive Non-Hodgkin Lymphoma

description: Stage II: Involvement of two or more lymph node regions on the same side of the diaphragm (II) or localized involvement of a single associated extralymphatic organ or site and its regional lymph nodes with or without other lymph node regions on the same side of the diaphragm (IIE). Note: The number of lymph node regions involved may be indicated by a subscript (e.g., II3). (from PDQ)


name: AIDS-Related Primary Diffuse Large B-Cell Lymphoma of the Central Nervous System

description: A diffuse large B-cell lymphoma that arises from the central nervous system in AIDS patients.


description: ALK-negative anaplastic large cell lymphoma (ALK- ALCL) is a type of ALCL, a rare and aggressive peripheral T-cell non-Hodgkin lymphoma affecting lymph nodes and extranodal sites, which is characterized by the lack of expression of a protein called anaplastic lymphoma kinase (ALK).


name: Mature T- and NK-Cell Lymphoma by Ann Arbor Stage

description: An anatomic stage for mature T- and NK-cell non-Hodgkin lymphomas based on the Ann Arbor classification criteria.


Mantle Cell Lymphoma by Ann Arbor Stage

description: An anatomic stage for mantle cell lymphoma based on the Ann Arbor classification criteria.


name: Angioimmunoblastic T-cell lymphoma stage I

description: Ann Arbor Classification: Stage I: Involvement of a single lymph node region (I); or localized involvement of a single extralymphatic organ or site in the absence of any lymph node involvement (IE).


Primary Uveal Non-Hodgkin Lymphoma

description: An indolent, low-grade B-cell non-Hodgkin lymphoma that arises from the choroid, iris, or ciliary body. It is characterized by the presence of a diffuse infiltrate of small, round lymphocytes. Lymphoid follicles with germinal centers may be present. In the past these tumors were termed 'reactive lymphoid hyperplasia'. Now they are considered low-grade B-cell lymphomas, most commonly extranodal marginal zone lymphomas of mucosa-associated lymphoid tissue.


name: Stage III Indolent Adult Non-Hodgkin Lymphoma

description: Ann Arbor Classification: Stage III: Involvement of lymph node regions on both sides of the diaphragm (III), which also may be accompanied by extralymphatic extension in association with adjacent lymph node involvement (IIIE) or by involvement of the spleen (IIIS) or both (IIIE,S).


Centroblastic lymphoma recurrent

description: The reemergence of centroblastic lymphoma after a period of remission.


name: Recurrent Primary Cutaneous Diffuse Large B-Cell Lymphoma

description: The reemergence of primary cutaneous diffuse large B-cell lymphoma after a period of remission.


name: Stage IB Mycosis Fungoides and Sezary Syndrome AJCC v8

description: Stage IB includes: T2, N0, M0, B0,1. T2: Patches, papules, or plaques covering 10% or more of the skin surface. N0: No clinically abnormal peripheral lymph nodes; biopsy not required. M0: No visceral organ involvement. B0: Absence of significant blood involvement: 5% or less of peripheral blood lymphocytes are atypical (Sezary cells). B1: Low blood tumor burden: more than 5% of peripheral blood lymphocytes are atypical (Sezary cells) but does not meet the criteria of B2. (AJCC 8th ed.)


name: Ann Arbor Stage IV Mature T- and NK-Cell Lymphoma

description: Ann Arbor Classification: Stage IV: Diffuse or disseminated involvement of one or more extralymphatic organs, with or without associated lymph node involvement; or isolated extralymphatic organ involvement in the absence of adjacent regional lymph node involvement, but in conjunction with disease in distant site(s); or any involvement of the liver or bone marrow, lungs (other than by direct extension from another site), or cerebrospinal fluid.


Mycosis fungoides refractory

description: Mycosis fungoides resistant to treatment.


name: Stage IIB Mycosis Fungoides and Sezary Syndrome AJCC v7

description: Stage IIB includes: T3, N0-2, M0, B0-1.  T3: One or more tumors (equal or greater than 1 cm diameter).  N0: No clinically abnormal peripheral lymph nodes; biopsy not required.  N1: Clinically abnormal peripheral lymph nodes; histopathology Dutch grade 1 or NCI LN0-2.  N2: Clinically abnormal peripheral lymph nodes; histopathology Dutch grade 2 or NCI LN3.  M0: No visceral organ involvement.  B0: Absence of significant blood involvement: 5% or less of peripheral blood lymphocytes are atypical (Sezary cells).  B1: Low blood tumor burden: more than 5% of peripheral blood lymphocytes are atypical (Sezary cells) but does not meet the criteria of B2.  (AJCC 7th ed.)


marginal zone lymphoma

description: A usually indolent mature B-cell lymphoma, arising from the marginal zone of lymphoid tissues. It is characterized by the presence of small to medium sized atypical lymphocytes. It comprises three entities, according to the anatomic sites involved: extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue, which affects extranodal sites (most often stomach, lung, skin, and ocular adnexa); nodal marginal zone B-cell lymphoma, which affects lymph nodes without evidence of extranodal disease; and splenic marginal zone B-cell lymphoma, which affects the spleen and splenic hilar lymph nodes, bone marrow, and often the peripheral blood.


name: Systemic Anaplastic Large Cell Lymphoma, ALK-Positive

description: A T-cell peripheral lymphoma affecting multiple anatomic sites. It is composed of usually large, pleomorphic, CD30 positive T-lymphocytes with abundant cytoplasm. It is characterized by the presence of a translocation involving the ALK gene and expression of ALK fusion protein.


Follicular Helper T-Cell Lymphoma

description: A group of node-based peripheral T-cell lymphomas with phenotypic features of T follicular helper (TFH) cells. This category includes the following: follicular helper T-cell lymphoma, angioimmunoblastic-type; follicular helper T-cell lymphoma, follicular-type; and follicular helper T-cell lymphoma, not otherwise specified.


name: Recurrent Follicular Helper T-Cell Lymphoma

description: The reemergence of follicular helper T-cell lymphoma after a period of remission.


splenic mantle cell lymphoma

description: A mantle cell lymphoma occurring in the spleen.


name: Recurrent Transformed Marginal Zone Lymphoma to Diffuse Large B-Cell Lymphoma

description: The reemergence of diffuse large B-cell lymphoma that resulted from the transformation of marginal zone lymphoma, after a period of remission.


Recurrent Burkitt Lymphoma

description: The reemergence of Burkitt lymphoma after a period of remission.


Prostate Diffuse Large B-Cell Lymphoma

description: A rare diffuse large B-cell lymphoma that arises from the prostate gland.


name: Monomorphic epitheliotropic intestinal T-cell lymphoma

description: A mature T-cell and NK-cell non-Hodgkin lymphoma of intraepithelial T-lymphocytes. It usually arises from the small intestine. A minority of cases arise from the large intestine or the stomach. It is characterized by the presence of a monomorphic cellular infiltrate of small to medium-sized T-lymphocytes that are cytotoxic and express CD56. It is not associated with celiac disease.


name: large B-cell diffuse lymphoma of salivary gland

description: A diffuse large B-cell lymphoma that manifests initially in a salivary gland. It usually occurs in the parotid gland.


name: Ann Arbor Stage II Grade 1 Follicular Lymphoma

description: Ann Arbor Classification: Stage II: Involvement of two or more lymph node regions on the same side of the diaphragm (II); or localized involvement of a single extralymphatic organ or site in association with regional lymph node involvement with or without involvement of other lymph node regions on the same side of the diaphragm (IIE).


name: Childhood Anaplastic Large Cell Lymphoma

description: An anaplastic large cell lymphoma that occurs during childhood.


name: Anaplastic Lymphoma Post-Transplant Lymphoproliferative Disorder

description: An anaplastic lymphoma that arises in a patient with a history of organ transplantation.


name: Stage IV Indolent Adult Non-Hodgkin Lymphoma


enteropathy-associated T-cell lymphoma

description: An uncommon mature T-cell lymphoma of intraepithelial lymphocytes. It usually arises from the small intestine, most commonly the jejunum or ileum. Other less frequent primary anatomic sites include the duodenum, stomach, colon, or outside the gastrointestinal tract. It is seen with increased frequency in regions with a high prevalence of celiac disease.


name: Ann Arbor Stage III Grade 3 Follicular Lymphoma

description: Ann Arbor Classification: Stage III: Involvement of lymph node regions on both sides of the diaphragm (III), which also may be accompanied by extralymphatic extension in association with adjacent lymph node involvement (IIIE) or by involvement of the spleen (IIIS) or both (IIIE,S).


T-cell lymphoma stage II

description: Ann Arbor Classification: Stage II: Involvement of two or more lymph node regions on the same side of the diaphragm (II); or localized involvement of a single extralymphatic organ or site in association with regional lymph node involvement with or without involvement of other lymph node regions on the same side of the diaphragm (IIE). The number of regions involved may be indicated by a subscript (e.g., II3).


name: Refractory Primary Cutaneous Anaplastic Large Cell Lymphoma

description: Primary cutaneous anaplastic large cell lymphoma that is resistant to treatment.


name: nodular lymphocyte predominant Hodgkin lymphoma

description: A monoclonal B-cell neoplasm characterized by a nodular, or a nodular and diffuse proliferation of scattered large neoplastic cells known as popcorn or lymphocyte predominant cells (LP cells)- formerly called L&H cells for lymphocytic and/or histiocytic Reed-Sternberg cell variants. The LP cells lack CD15 and CD30 in nearly all instances. Patients are predominantly male, frequently in the 30-50 year age group. Most patients present with limited stage disease (localized peripheral lymphadenopathy, stage I or II). (WHO 2008)


Sezary syndrome refractory

description: Sezary syndrome that is resistant to treatment.


follicular lymphoma of spleen

description: A follicular lymphoma occurring in the spleen.


name: Refractory Transformed Follicular Lymphoma to Diffuse Large B-Cell Lymphoma

description: Transformed follicular lymphoma to diffuse large B-cell lymphoma that is resistant to treatment.


name: central nervous system anaplastic large cell lymphoma

description: An anaplastic large cell lymphoma that affects the brain, meninges, or spinal cord.


name: Ann Arbor Stage II Grade 1 Contiguous Follicular Lymphoma


name: Lacrimal Gland Mucosa-Associated Lymphoid Tissue Lymphoma

description: A mucosa-associated lymphoid tissue lymphoma that arises from the lacrimal gland.


name: Hodgkin-Like Adult T-Cell Leukemia/Lymphoma

description: A rare morphologic variant of adult T-cell leukemia/lymphoma characterized by the presence of Hodgkin-like and Reed-Sternberg-like cells.


name: Follicular Helper T-Cell Lymphoma, Angioimmunoblastic-Type by Ann Arbor Stage

description: An anatomic stage for follicular helper T-cell lymphoma, angioimmunoblastic-type  based on the Ann Arbor classification criteria.


Triple hit lymphoma

description: High-grade B-cell lymphoma characterized by the abnormal rearrangement of MYC gene, BCL2 gene, and BCL6 gene. Patients with this type of lymphoma usually respond poorly to standard treatments and have a poor prognosis.


description: Waldenstrom macroglobulinemia that does not respond to treatment.


name: Ann Arbor Stage III Aggressive Adult Non-Hodgkin Lymphoma


Blastoid Variant Mantle Cell Lymphoma

description: An aggressive mantle cell lymphoma characterized by the presence of neoplastic B-lymphocytes resembling lymphoblasts.


name: thyroid gland diffuse large B-cell lymphoma

description: A diffuse large B-cell lymphoma primarily involving the thyroid gland.


name: Ann Arbor Stage I Grade 2 Follicular Lymphoma

description: Ann Arbor Classification: Stage I: Involvement of a single lymph node region (I); or localized involvement of a single extralymphatic organ or site in the absence of any lymph node involvement (IE).


name: Precursor B-lymphoblastic lymphoma stage III


name: BCL2-R-Negative, CD23-Positive Follicle Center Lymphoma

description: Follicular lymphoma characterized by the absence of BCL2 rearrangement and the presence of CD23-positive neoplastic cells. It is associated with STAT6 mutations. It presents with low-stage disease, typically in the inguinal region, and often has a predominant diffuse growth pattern.


name: Ann Arbor Stage II Grade 2 Contiguous Follicular Lymphoma

description: Ann Arbor Classification: Stage II: Involvement of two or more lymph node regions on the same side of the diaphragm (II); or localized involvement of a single extralymphatic organ or site in association with regional lymph node involvement with or without involvement of other lymph node regions on the same side of the diaphragm (IIE).


localized pagetoid reticulosis

description: A variant of mycosis fungoides, characterized by an exclusively intraepidermal atypical (cerebriform) lymphocytic infiltrate. Patients present with a localized psoriasiform or hyperkeratotic patch or plaque, usually in the extremities. Extracutaneous dissemination of the disease has never been reported.


nodal marginal zone B-cell lymphoma

description: Nodal marginal zone B-cell lymphoma is a rare, indolent B-cell non-Hodgkin lymphoma, characterized by abnormal clonal proliferation of mature B-lymphocytes with involvement of the lymph nodes, sometimes the bone marrow, and rarely the blood. Clinically it presents with disseminated peripheral, abdominal and/or thoracic lymphadenopathy. Cytopenia and bulky tumors (greater than 5 cm) are rare. Association with Hepatitis C virus and chronic inflammation has been reported.


name: Refractory Systemic Anaplastic Large Cell Lymphoma

description: Systemic anaplastic large cell lymphoma that does not respond to treatment.


name: Primary Vitreoretinal Non-Hodgkin Lymphoma

description: An uncommon and potentially fatal intraocular non-Hodgkin lymphoma that involves the uvea, retina, vitreous body, and optic nerve. It is a subset of primary central nervous system non-Hodgkin lymphoma. The majority of cases are diffuse large B-cell lymphomas.


grade 3B follicular lymphoma

description: A grade 3 follicular lymphoma composed of solid sheets of centroblasts.


Recurrent Hepatosplenic T-Cell Lymphoma

description: The reemergence of hepatosplenic T-cell lymphoma after a period of remission.


Grade III Lymphomatoid Granulomatosis

description: Lymphomatoid granulomatosis characterized by the presence of aggregates of neoplastic large B-lymphocytes, usually admixed with pleomorphic and Hodgkin-like cells, in a background of chronic inflammation.  Necrotic changes are present and are usually extensive.  Grade III lymphomatoid granulomatosis should be approached clinically as a subtype of diffuse large B-cell lymphoma.


name: Adult Systemic Anaplastic Large Cell Lymphoma

description: An anaplastic large cell lymphoma affecting multiple anatomic sites and occurring in adults.


name: Predominantly Diffuse Follicular Lymphoma with 1p36 Deletion

description: A predominantly diffuse, low-grade follicular lymphoma. It often presents as a large localized inguinal mass, lacks BCL2 rearrangement, and is associated with 1p36 deletion.


Colon Diffuse Large B-Cell Lymphoma

description: A diffuse large B-cell lymphoma that arises from the colon.  It is the most frequent type of lymphoma found in the colon.


Mycosis fungoides stage I

description: Stage I includes: IA (T1, N0, M0, B0-1); IB (T2, N0, M0, B0-1). T1: Limited patches, papules, and/or plaques covering less than 10% of the skin surface.  May further stratify into T1a (patch only) vs. T1b (plaque +/- patch).  T2: Patches, papules, or plaques covering 10% or more of the skin surface.  May further stratify into T2a (patch only) vs. T2b (plaque +/- patch).  N0: No clinically abnormal peripheral lymph nodes; biopsy not required.  M0: No visceral organ involvement.  B0: Absence of significant blood involvement: 5% or less of peripheral blood lymphocytes are atypical (Sezary cells).  B1: Low blood tumor burden: more than 5% of peripheral blood lymphocytes are atypical (Sezary cells) but does not meet the criteria of B2.  (AJCC 7th ed.)


name: Stage III Childhood Anaplastic Large Cell Lymphoma

description: Ann Arbor Classification: Stage III: Involvement of lymph node regions on both sides of the diaphragm (III), which also may be accompanied by extralymphatic extension in association with adjacent lymph node involvement (IIIE) or by involvement of the spleen (IIIS) or both (IIIE,S).


name: Nodal marginal zone B-cell lymphoma stage II


Childhood Immunoblastic Lymphoma

description: An immunoblastic lymphoma (a variant of diffuse large B-cell lymphoma) occurring in children.


Prostate Mantle Cell Lymphoma

description: A rare mantle cell lymphoma that arises from the prostate gland.


description: The reemergence of lymphoplasmacytic lymphoma after a period of remission.


name: Refractory Transformed T-cell Non-Hodgkin Lymphoma

description: An indolent T-cell non-Hodgkin lymphoma which has undergone histologic transformation to an aggressive T-cell non-Hodgkin lymphoma and has become resistant to treatment.


Non-Hodgkin Lymphoma by Ann Arbor Stage

description: An anatomic stage for non-Hodgkin lymphomas based on the Ann Arbor classification criteria.


name: Stage IVB Mycosis Fungoides and Sezary Syndrome AJCC v7

description: Stage IVB includes: T1-4, N0-3, M1, B0-2. T1: Limited patches, papules, and/or plaques covering less than 10% of the skin surface.  May further stratify into T1a (patch only) vs. T1b (plaque +/- patch).  T2: Patches, papules, or plaques covering 10% or more of the skin surface.  May further stratify into T2a (patch only) vs. T2b (plaque +/- patch).  T3: One or more tumors (equal or greater than 1 cm diameter).  T4: Confluence of erythema covering 80% or more of body surface area.  N0: No clinically abnormal peripheral lymph nodes; biopsy not required.  N1: Clinically abnormal peripheral lymph nodes; histopathology Dutch grade 1 or NCI LN0-2.  N2: Clinically abnormal peripheral lymph nodes; histopathology Dutch grade 2 or NCI LN3.  N3: Clinically abnormal peripheral lymph nodes; histopathology Dutch grades 3-4 or NCI LN4; clone positive or negative.  M1: Visceral involvement (must have pathology confirmation and organ involved should be specified).  B0: Absence of significant blood involvement: 5% or less of peripheral blood lymphocytes are atypical (Sezary cells).  B1: Low blood tumor burden: more than 5% of peripheral blood lymphocytes are atypical (Sezary cells) but does not meet the criteria of B2.  B2: High blood tumor burden: 1000/microL Sezary cells or more with positive clone.  (AJCC 7th ed.)


name: Lymphoplasmacytoid lymphoma/immunocytoma stage III


name: Refractory Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma

description: Mature T-cell and NK-cell non-Hodgkin lymphoma that is resistant to treatment.


name: AIDS-Related Non-Hodgkin Lymphoma of the Cervix

description: A non-Hodgkin lymphoma that arises from the cervix in a patient with acquired immunodeficiency syndrome.


name: Liver Mucosa-Associated Lymphoid Tissue Lymphoma

description: A rare mucosa-associated lymphoid tissue lymphoma that arises from the liver.  It is characterized by the presence of centrocyte-like cells surrounding germinal centers.  Lymphoepithelial lesions involving the bile duct epithelium may also be present.


Cyclin D1-Positive Mantle Cell Lymphoma

description: A molecular subtype of mantle cell lymphoma characterized by the presence of cyclin D1 expression and/or CCND1 rearrangement..


Mature B-Cell Non-Hodgkin Lymphoma

description: A non-Hodgkin lymphoma that originates from mature B lymphocytes. Representative examples include diffuse large B-cell lymphoma, follicular lymphoma, marginal zone lymphoma, mantle cell lymphoma, and small lymphocytic lymphoma.


name: small cell variant anaplastic large cell lymphoma

description: A histologic variant of anaplastic large cell lymphoma characterized by the presence of a predominant population of small to medium size malignant cells with irregular nuclei.


name: Ann Arbor Stage II Non-Contiguous Mantle Cell Lymphoma

description: Stage II: Involvement of two or more lymph node regions on the same side of the diaphragm (II) or localized involvement of a single associated extralymphatic organ or site and its regional lymph nodes with or without other lymph node regions on the same side of the diaphragm (IIE). Note: The number of lymph node regions involved may be indicated by a subscript (e.g., II3). (from PDQ)


name: Ann Arbor Stage I Aggressive Adult Non-Hodgkin Lymphoma

description: Ann Arbor Classification: Stage I: Involvement of a single lymph node region (I); or localized involvement of a single extralymphatic organ or site in the absence of any lymph node involvement (IE).


Refractory Gray-Zone Lymphoma

description: Gray-zone lymphoma that is resistant to treatment.


name: Anaplastic large cell lymphoma T- and null-cell types refractory

description: Anaplastic large cell lymphoma resistant to treatment.


Mediastinal Non-Hodgkin Lymphoma

description: Non-Hodgkin lymphoma arising from the mediastinum.


name: Chlamydia Psittaci-Associated Ocular Adnexal Mucosa-Associated Lymphoid Tissue Lymphoma

description: Mucosa-associated lymphoid tissue lymphoma that arises from the ocular adnexa and caused by stimulation of lymphoid tissue due to Chlamydia psittaci bacterial infection.


Colorectal Burkitt Lymphoma

description: A rare Burkitt lymphoma that arises from the colon or rectum.


name: Recurrent Systemic Anaplastic Large Cell Lymphoma

description: The reemergence of systemic anaplastic large cell lymphoma after a period of remission.


Stage IV Diffuse Large B-Cell Lymphoma

description: Ann Arbor Classification: Stage IV: Diffuse or disseminated involvement of one or more extralymphatic organs, with or without associated lymph node involvement; or isolated extralymphatic organ involvement in the absence of adjacent regional lymph node involvement, but in conjunction with disease in distant site(s); or any involvement of the liver or bone marrow, lungs (other than by direct extension from another site), or cerebrospinal fluid.


Colon Mantle Cell Lymphoma

description: A mantle cell lymphoma that arises from the colon.  It often presents as a polypoid lesion.


name: Smoldering Adult T-Cell Leukemia/Lymphoma

description: An adult T-cell leukemia/lymphoma characterized by less than 5% neoplastic lymphocytes in the peripheral blood, absence of lymphadenopathy and hypercalcemia, and occasional skin or pulmonary lesions.


follicular malignant lymphoma of breast

description: A follicular lymphoma that arises from the breast as a primary tumor.


protein FosB isoform 1 (mouse)

A protein FosB isoform 1 that is encoded in the genome of mouse.


name: PI5PA_RAT Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (sprot)

description: A phosphatidylinositol 4,5-bisphosphate 5-phosphatase A that is encoded in the genome of rat.


name: ankyrin repeat and SOCS box protein 16 isoform 1 (human)

description: An ankyrin repeat and SOCS box protein 16 isoform 1 that is encoded in the genome of human.


name: GDPP1_DANRE GDP-D-glucose phosphorylase 1 (sprot)

description: A GDP-D-glucose phosphorylase 1 that is encoded in the genome of zebrafish.


pannexin-1 isoform 1 (mouse)

A pannexin-1 isoform 1 that is encoded in the genome of mouse.


PANX1_MOUSE Pannexin-1 (sprot)

A pannexin-1 that is encoded in the genome of mouse.


name: CDN1C_HUMAN Cyclin-dependent kinase inhibitor 1C (sprot)

description: A cyclin-dependent kinase inhibitor 1C that is encoded in the genome of human.


name: cyclin-dependent kinase inhibitor 1C isoform Long (human)

description: A cyclin-dependent kinase inhibitor 1C (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P49918-1.


name: cyclin-dependent kinase inhibitor 1C phosphorylated 1 (human)

description: A cyclin-dependent kinase inhibitor 1C (human) that has been phosphorylated on the residue at the position equivalent to Tyr-91 of the amino acid sequence represented by UniProtKB:P49918-1. Example: UniProtKB:P49918-1, Tyr-91, MOD:00048.


name: cyclin-dependent kinase inhibitor 1C isoform Short (human)

description: A cyclin-dependent kinase inhibitor 1C (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P49918-2.


name: RLF23_ARATH Rapid alkalinization factor 23 (sprot)

description: A protein that is a translation product of the RALF23 gene in Arabidopsis thaliana.


AIR1_SCHPO Protein air1 (sprot)

A protein that is a translation product of the air1 gene in Schizosaccharomyces pombe 972h-.


name: Charcot-Marie-Tooth disease X-linked recessive 3

description: X-linked Charcot-Marie-Tooth disease type 3 is a rare, genetic, peripheral sensorimotor neuropathy characterized by an X-linked recessive inheritance pattern and the childhood- to adolescent-onset of progressive, distal muscle weakness and atrophy (beginning in the lower extremities and then affecting the upper extremities), as well as distal, pansensory loss in the upper and lower extremities, pes cavus, and absent or reduced distal tendon reflexes. Pain and paresthesia are frequently the initial sensory symptoms. Spastic paraparesis (manifested by clasp-knife sign, hyperactive deep-tendon reflexes, and Babinski sign) has also been reported.


Charcot-Marie-Tooth disease type X

description: A subtype of Charcot-Marie-Tooth disease with genetic defects on the X chromosome.


name: Charcot-Marie-Tooth disease X-linked recessive 4

description: X-linked Charcot-Marie-Tooth disease type 4 is a rare, genetic, axonal, peripheral sensorimotor neuropathy characterized by an X-linked recessive inheritance pattern and the neonatal- to early childhood-onset of severe, slowly progressive, distal muscle weakness and atrophy (in particular of the peroneal group), as well as sensory impairment (with the lower extremities being more affected than the upper extremities), pes cavus, areflexia and hammertoes. Sensorineural hearing loss and cognitive impairment may also be associated. Females are asymptomatic and do not display the phenotype.


name: Charcot-Marie-Tooth disease X-linked recessive 5

description: X-linked Charcot-Marie-Tooth disease type 5 is a rare, genetic, peripheral sensorimotor neuropathy characterized by an X-linked recessive inheritance pattern and the infancy- to childhood-onset of: 1) progressive distal muscle weakness and atrophy (first appearing and more prominent in the lower extremities than the upper) which usually manifests with foot drop and gait disturbance, 2) bilateral, profound, prelingual sensorineural hearing loss and 3) progressive optic neuropathy. Females are asymptomatic and do not display the phenotype.


name: Charcot-Marie-Tooth disease X-linked dominant 1

description: Charcot-Marie-Tooth neuropathy that is inherited in an X-linked manner, and is associated with mutation(s) in the GJB1 gene, encoding gap junction beta-1 protein. The condition is characterized by moderate to severe motor and sensory neuropathy in males, and mild to no symptoms in females.


name: Charcot-Marie-Tooth disease X-linked recessive 2

description: X-linked Charcot-Marie-Tooth disease type 2 is a rare, genetic, peripheral sensorimotor neuropathy characterized by an X-linked recessive inheritance pattern and the infantile- to childhood-onset of progressive, distal muscle weakness and atrophy (more prominent in the lower extremities than in the upper extremities), pes cavus, and absent tendon reflexes. Sensory impairment and intellectual disability has been reported in some individuals.


name: Charcot-Marie-Tooth disease X-linked dominant 6

description: X-linked Charcot-Marie-Tooth disease type 6 is a rare, genetic, principally axonal, peripheral sensorimotor neuropathy characterized by an X-linked dominant inheritance pattern and the childhood-onset of slowly progressive, moderate to severe, distal muscle weakness and atrophy of the lower extremities, as well as distal, panmodal sensory abnormalities, bilateral foot deformities (pes cavus, clawed toes), absent ankle reflexes and gait abnormalities (steppage gait). Females are usually asymptomatic or only present mild manifestations (mild postural hand tremor, mild wasting of hand intrinsic muscles).


brugunin A

A  lignan isolated from the stems of Sinocalamus affinis.


name: partitioning defective 3 homolog isoform 1 (mouse)

description: A partitioning defective 3 homolog (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q99NH2-1.


KGB1_CAEEL GLH-binding kinase 1 (sprot)

A protein that is a translation product of the kgb-1 gene in worm.


name: bladder cancer-associated protein isoform 1 (rat)

description: A bladder cancer-associated protein isoform 1 that is encoded in the genome of rat.


N(1)-methyladenosine 5'-monophosphate

A purine ribonucleoside 5'-monophosphate that is AMP monomethylated on N(1).


statin (semi-synthetic)

A statin that is derived from a naturally occurring statin by partial chemical synthesis.


PRAVASTATIN SODIUM

An organic sodium salt that is the sodium salt of pravastatin. A reversible inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA), it is used for lowering cholesterol and preventing cardiovascular disease. It is one of the lower potency statins, but has the advantage of fewer side effects compared with lovastatin and simvastatin.


name: MACF1_MOUSE Microtubule-actin cross-linking factor 1, isoforms 1/2/3/4 (sprot)

description: A microtubule-actin cross-linking factor 1 that is encoded in the genome of mouse.


name: microtubule-actin cross-linking factor 1 cysteinylated 1 (mouse)

description: A microtubule-actin cross-linking factor 1 (mouse) that has been cysteinylated on the residue at the position equivalent to Cys-1063 of the amino acid sequence represented by UniProtKB:Q9QXZ0-1. Example: UniProtKB:Q9QXZ0-1, Cys-1063, MOD:00765.


name: protein spinster homolog 3 isoform m1 (mouse)

description: A protein spinster homolog 3 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9D232-1.


protein spinster homolog 3

A protein that is a translation product of the human SPNS3 gene or a 1:1 ortholog thereof.


name: protein spinster homolog 3 isoform h2 (human)

description: A protein spinster homolog 3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q6ZMD2-2.


name: protein spinster homolog 3 isoform m2 (mouse)

description: A protein spinster homolog 3 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9D232-2.


name: SPNS3_DANRE Protein spinster homolog 3 (sprot)

description: A protein spinster homolog 3 that is encoded in the genome of zebrafish.


name: SPNS3_MOUSE Protein spinster homolog 3 (sprot)

description: A protein spinster homolog 3 that is encoded in the genome of mouse.


name: protein spinster homolog 3 cysteinylated 1 (mouse)

description: A protein spinster homolog 3 (mouse) that has been cysteinylated on the residue at the position equivalent to Cys-56 of the amino acid sequence represented by UniProtKB:Q9D232-1. Example: UniProtKB:Q9D232-1, Cys-56, MOD:00765.


name: protein spinster homolog 3 isoform h1 (human)

description: A protein spinster homolog 3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q6ZMD2-1.


name: SPNS3_HUMAN Protein spinster homolog 3 (sprot)

description: A protein spinster homolog 3 that is encoded in the genome of human.


name: eukaryotic translation initiation factor 4E-binding protein 1 isoform 1 phosphorylated 1

description: A eukaryotic translation initiation factor 4E-binding protein 1 isoform 1 that has been phosphorylated by activated mTORC1. Example: UniProtKB:Q13541-1, 2-118, Thr-37/Thr-46, MOD:00047.


name: eukaryotic translation initiation factor 4E-binding protein 1 isoform 1

description: A eukaryotic translation initiation factor 4E-binding protein 1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q13541-1 or a 1:1 ortholog thereof.


name: eukaryotic translation initiation factor 4E-binding protein 1 isoform 1, initiator methionine removed form

description: A eukaryotic translation initiation factor 4E-binding protein 1 isoform 1 that has had the initiator methionine removed.


name: eukaryotic translation initiation factor 4E-binding protein 1 isoform 1 phosphorylated 1 (human)

description: A eukaryotic translation initiation factor 4E-binding protein 1 isoform 1 phosphorylated 1 in human. UniProtKB:Q13541-1, 2-118, Thr-37/Thr-46, MOD:00047.


name: eukaryotic translation initiation factor 4E-binding protein 1 isoform 1 phosphorylated 2 (rat)

description: A eukaryotic translation initiation factor 4E-binding protein 1 isoform 1 phosphorylated 2 in rat. UniProtKB:Q62622-1, Ser-64, MOD:00046.


name: eukaryotic translation initiation factor 4E-binding protein 1 isoform 1 phosphorylated 2

description: A eukaryotic translation initiation factor 4E-binding protein 1 isoform 1 that has been phosphorylated by MAP kinases. Example: UniProtKB:Q62622-1, Ser-64, MOD:00046.


name: eukaryotic translation initiation factor 4E-binding protein 1 isoform 1 (mouse)

description: A eukaryotic translation initiation factor 4E-binding protein 1 isoform 1 that is encoded in the genome of mouse.


name: eukaryotic translation initiation factor 4E-binding protein 1 isoform 1 (human)

description: A eukaryotic translation initiation factor 4E-binding protein 1 isoform 1 that is encoded in the genome of human.


hippocampal sclerosis of aging

description: Age-related neuropathological condition with severe neuronal cell loss and gliosis in the hippocampus


prosaposin N-glycosylated 94 (human)

A prosaposin (human) that has been N-glycosylated at the residue equivalent to Asn-80 of the amino acid sequence represented by UniProtKB:P07602-1, in which the glycan structure is represented by GlyTouCan:G82348BZ. Example: UniProtKB:P07602-1, Asn-80, MOD:00160~GNO:G82348BZ.


name: transcription initiation factor TFIID subunit 8 isoform h1 (human)

description: A transcription initiation factor TFIID subunit 8 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q7Z7C8-1.


name: FDHF_ECOLI Formate dehydrogenase H (sprot)

description: A formate dehydrogenase H that is encoded in the genome of Escherichia coli K-12.


formate dehydrogenase H

A protein that is a translation product of the Escherichia coli K-12 fdhF gene or a 1:1 ortholog thereof.


name: FDHL_STAA8 Putative formate dehydrogenase SAOUHSC_02582 (sprot)

description: A formate dehydrogenase H that is encoded in the genome of Staphylococcus aureus subsp. aureus NCTC 8325.


name: cyclin-D-binding Myb-like transcription factor 1 isoform m1 (mouse)

description: A cyclin-D-binding Myb-like transcription factor 1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8CE22-1.


name: kinesin-like protein KIF3B deaminated 1 (human)

description: A kinesin-like protein KIF3B (human) that has been deaminated on the residue at the position equivalent to Asn-323 of the amino acid sequence represented by UniProtKB:O15066-1. Example: UniProtKB:O15066-1, Asn-323, MOD:00684.


name: KIF3B_HUMAN Kinesin-like protein KIF3B (sprot)

description: A kinesin-like protein KIF3B that is encoded in the genome of human.


name: kinesin-like protein KIF3B isoform 1 (human)

description: A kinesin-like protein KIF3B isoform 1 that is encoded in the genome of human.


name: kinesin-like protein KIF3B isoform h2 (human)

description: A kinesin-like protein KIF3B (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O15066-2.


Benign cyst of ovary

description: A non-malignant ovarian cyst.


corpus luteum cyst

description: A ovarian cyst (disease) that involves the corpus luteum.


name: Large Solitary Luteinized Follicle Cyst of Ovary

description: A large, unilateral, solitary ovarian cyst lined by luteinized cells, occurring during pregnancy or puerperium. (WHO 2020)


Complex ovarian cyst

description: A cystic lesion that arises from the ovary. It is characterized by the presence of cystic spaces that contain fluid and a solid tissue component.


Unilocular Ovarian Cyst

category: biolink:PhenotypicFeature biolink:DiseaseOrPhenotypicFeature biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing

description: An ovarian cyst that has a single compartment.


Follicular cyst of ovary

description: A benign ovarian cyst that develops from a persistent, unruptured Graafian follicle, which grows larger than three centimeters.


Autonomous Ovarian Follicular Cyst

description: A cyst arising from an ovarian follicle that produces hormones independent of gonadotropin stimulation.


Functional cyst of ovary

description: A benign ovarian cyst that develops and regresses during the menstrual cycle as part of normal ovarian function.


DEFA9_MOUSE Alpha-defensin 9 (sprot)

A defensin-related cryptdin-9 that is encoded in the genome of mouse.


name: RS18_DICDI Small ribosomal subunit protein uS13 (sprot)

description: A eukaryotic-type small ribosomal subunit protein uS13 that is encoded in the genome of Dictyostelium discoideum.


name: transmembrane protein 182 isoform 1 (human)

description: A transmembrane protein 182 isoform 1 that is encoded in the genome of human.


transmembrane protein 182 isoform 1

A transmembrane protein 182 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q6ZP80-1 or a 1:1 ortholog thereof.


name: transmembrane protein 182 isoform 1 (mouse)

description: A transmembrane protein 182 isoform 1 that is encoded in the genome of mouse.


A lysophosphatidylethanolamine zwitterion in which the remaining acyl group (position not specified) contains 14 carbons and 2 double bonds.


name: Y6537_DICDI Putative uncharacterized protein DDB_G0280355 (sprot)

description: A protein that is a translation product of the DDB_G0280355 gene in Dictyostelium discoideum.


name: sorbin and SH3 domain-containing protein 2 isoform h11 (human)

description: A sorbin and SH3 domain-containing protein 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O94875-11.


name: PUB21_ARATH U-box domain-containing protein 21 (sprot)

description: A protein that is a translation product of the PUB21 gene in Arabidopsis thaliana.


tricyclene

A monoterpene that is tricyclo[2.2.1.0(2,6)]heptane bearing a three additional methyl substituents (one at position 1 and two at position 7).


name: saturated organic heteromonocyclic parent


A saturated organic heteromonocyclic parent that is cyclohexane in which the carbon atoms at positions 1, 3 and 5 are replaced by oxygen atoms.


thietane

An organosulfur heterocyclic compound containing a saturated four membered ring with 3 carbon atoms and 1 sulfur atom.


TANEGOOL

A lignan that consists of tetrahydrofuran ring substituted by a 4-hydroxy-3-methoxyphenyl group at position 5, a hydroxyphenyl group at position 4 and a hydroxy(4-hydroxy-3-methoxyphenyl)methyl group at position 3. It has been isolated from Taxus yunnanensis.


A crown ether that is cyclooctadecane in which the carbon atoms at positions 1, 4, 7, 10, 13 and 16 have been replaced by oxygen atoms.


Major microspecies at pH 7.3.


A crown thioether that is cyclododecane in which the carbon atoms at positions 1, 4, 7 and 10 are replaced by sulfur atoms.


An azacycloalkane that is cyclododecane in which the carbon atoms at positions 1, 4, 7 and 10 are replaced by nitrogen atoms.


oxathiocane

A saturated organic heteromonocyclic parent that is cyclooctane in which one methylene group has been replaced by an oxygen and another methylene group has been replaced by a sulphur.


dioxane

Any member of the class of dioxanes that is a cyclohexane in which two carbon atoms are replaced by oxygen atoms.


oxepane

A saturated organic heteromonocyclic parent that is cycloheptane in which one of the methylene groups is replaced by oxygen.


A crown ether that is cyclododecane in which the carbon atoms at positions 1, 4, 7 and 10 have been replaced by oxygen atoms.


dithianes

An organosulfur heterocyclic compound containing a six-member aliphatic saturated heterocycle made up of two sulfur atoms and four carbon atoms.


A crown ether that is cyclononane in which the carbon atoms at positions 1, 4, and 7 have been replaced by oxygen atoms.


oxane

A saturated organic heteromonocyclic parent that is cyclohexane in which one of the carbon atoms has been replaced by an oxygen atom.


thiazolidine

A saturated organic heteromonocyclic parent comprising a five-membered ring with a sulfur at position 1 and a nitrogen at either position 2 or 3.


An oxathiocane in which the oxygen and sulfur atoms are at positions 1 and 5 respectively.


THIOMORPHOLINE

A saturated organic heteromonocyclic parent that is an analogue of morpholine where the oxygen atom is replaced by sulfur.


MORPHOLINE

An organic heteromonocyclic compound whose six-membered ring contains four carbon atoms and one nitrogen atom and one oxygen atom that lies opposite to each other; the parent compound of the morpholine family.


AZEPANE

An azacycloalkane that is cycloheptane in which one of the carbon atoms is replaced by a nitrogen atom.


A crown thioether that is cyclononane in which the carbon atoms at positions 1, 4 and 7 are replaced by sulfur atoms. It is a tridentate thioether ligand that is used to synthesise complexes with a wide variety of transition metal ions.


trithiane

An organosulfur heterocyclic compound containing a six-member aliphatic saturated heterocycle made up of three sulfur atoms and three carbon atoms.


pyrazolidine

An azacycloalkane that is the 1,2-diaza derivative of cyclopentane


Major microspecies at pH 7.3.


oxetane

A saturated organic heteromonocyclic parent that is a four-membered ring comprising of three carbon atoms and an oxygen atom.


name: extracellular serine/threonine protein kinase FAM20C isoform h1 (human)

description: An extracellular serine/threonine protein kinase FAM20C (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8IXL6-1.


sterculic acid

A long-chain, monounsaturated fatty acid composed of 9-octadecenoic acid having a 9,10-cyclopropenyl group.


name: collagen alpha-6(IV) chain, signal peptide removed 5-hydroxy-lysine and 4-hydroxy-proline form (human)

description: A collagen alpha-6(IV) chain (human) that has had the signal peptide removed and that includes at least one 5-hydroxy-lysine and at least one 4-hydroxy-proline. UniProtKB:Q14031, 23-1691, MOD:00037|MOD:00039.


name: collagen alpha-6(IV) chain, signal peptide removed 5-hydroxy-lysine, 3-hydroxy-proline and 4-hydroxy-proline form (human)

description: A collagen alpha-6(IV) chain (human) that has had the signal peptide removed and that includes at least one 5-hydroxy-lysine, at least one 3-hydroxy-proline and at least one 4-hydroxy-proline. UniProtKB:Q14031, 23-1691, MOD:00037|MOD:00038|MOD:00039.


name: complement factor H N-glycosylated 52 (human)

description: A complement factor H (human) that has been N-glycosylated at the residue equivalent to Asn-911 of the amino acid sequence represented by UniProtKB:P08603-1, in which the glycan structure is represented by GlyTouCan:G42358LZ. Example: UniProtKB:P08603-1, Asn-911, MOD:00160~GNO:G42358LZ.


name: guanine nucleotide exchange protein SMCR8 isoform m1 (mouse)

description: A guanine nucleotide exchange protein SMCR8 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q3UMB5-1.


name: guanine nucleotide exchange protein SMCR8

description: A protein that is a translation product of the human SMCR8 gene or a 1:1 ortholog thereof.


name: SMR8A_DANRE Guanine nucleotide exchange protein smcr8a (sprot)

description: A guanine nucleotide exchange protein SMCR8 that is encoded in the genome of zebrafish.


name: guanine nucleotide exchange protein SMCR8 isoform h1 (human)

description: A guanine nucleotide exchange protein SMCR8 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8TEV9-1.


name: guanine nucleotide exchange protein SMCR8 isoform m2 (mouse)

description: A guanine nucleotide exchange protein SMCR8 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q3UMB5-2.


name: guanine nucleotide exchange protein SMCR8 methylated 1 (human)

description: A guanine nucleotide exchange protein SMCR8 (human) that has been methylated on the residue at the position equivalent to Cys-350 of the amino acid sequence represented by UniProtKB:Q8TEV9-1. Example: UniProtKB:Q8TEV9-1, Cys-350, MOD:00660.


name: SMCR8_HUMAN Guanine nucleotide exchange protein SMCR8 (sprot)

description: A guanine nucleotide exchange protein SMCR8 that is encoded in the genome of human.


name: guanine nucleotide exchange protein SMCR8 isoform h2 (human)

description: A guanine nucleotide exchange protein SMCR8 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8TEV9-2.


name: SMCR8_MOUSE Guanine nucleotide exchange protein SMCR8 (sprot)

description: A guanine nucleotide exchange protein SMCR8 that is encoded in the genome of mouse.


YIF1A_DANRE Protein YIF1A (sprot)

A protein YIF1A that is encoded in the genome of zebrafish.


name: NDUS7_MOUSE NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial (sprot)

description: An NADH-quinone oxidoreductase subunit B that is encoded in the genome of mouse.


carbonic anhydrase 2 isoform 1 (rat)

A vertebrate-type carbonic anhydrase 2 isoform 1 that is encoded in the genome of rat.


name: ATP-binding cassette sub-family D member 2 isoform 1 (mouse)

description: An ATP-binding cassette sub-family D member 2 isoform 1 that is encoded in the genome of mouse.


name: AT12B_ARATH Ubiquitin-like protein ATG12B (sprot)

description: A protein that is a translation product of the ATG12B gene in Arabidopsis thaliana.


name: microfibrillar-associated protein 3-like phosphorylated 1 (human)

description: A microfibrillar-associated protein 3-like (human) that has been phosphorylated on the residue at the position equivalent to Tyr-287 of the amino acid sequence represented by UniProtKB:O75121-1. Example: UniProtKB:O75121-1, Tyr-287, MOD:00048.


name: MFA3L_HUMAN Microfibrillar-associated protein 3-like (sprot)

description: A microfibrillar-associated protein 3-like that is encoded in the genome of human.


name: microfibrillar-associated protein 3-like isoform h3 (human)

description: A microfibrillar-associated protein 3-like (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O75121-3.


name: microfibrillar-associated protein 3-like isoform h2 (human)

description: A microfibrillar-associated protein 3-like (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O75121-2.


name: microfibrillar-associated protein 3-like isoform 1 (human)

description: A microfibrillar-associated protein 3-like isoform 1 that is encoded in the genome of human.


name: protein phosphatase Slingshot isoform 1 (fruit fly)

description: A protein phosphatase Slingshot (fruit fly) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q6NN85-1.


name: adenylosuccinate lyase isoform h1 (human)

description: An adenylosuccinate lyase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P30566-1.


erythronic acid

The erythro-isomer of  2,3,4-trihydroxybutanoic acid.


D-erythronic acid

An erythronic acid in which the stereocentres at positions 2 and 3 both have R-configuration (the D-enantiomer).


L-THREONIC ACID

The L-enantiomer of threonic acid.


name: alpha-endosulfine, initiator methionine removed phosphorylated 2 (human)

description: An alpha-endosulfine (human) that has had the initiator methionine removed and has been post-translationally modified to include phosphoserine at position 67 of the amino acid sequence represented by UniProtKB:O43768. UniProtKB:O43768, 2-121, Ser-67, MOD:00046.


CNTN3_HUMAN Contactin-3 (sprot)

A contactin-3 that is encoded in the genome of human.


A contactin that is a translation product of the human CNTN3 gene or a 1:1 ortholog thereof.


contactin-3 isoform 1 (human)

A contactin-3 isoform 1 that is encoded in the genome of human.


contactin-3 isoform 1

A contactin-3 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9P232-1 or a 1:1 ortholog thereof.


CNTN3_MOUSE Contactin-3 (sprot)

A contactin-3 that is encoded in the genome of mouse.


CNTN3_RAT Contactin-3 (sprot)

A contactin-3 that is encoded in the genome of rat.


contactin-3 isoform 1 (mouse)

A contactin-3 isoform 1 that is encoded in the genome of mouse.


contactin-3 citrullinated 1 (human)

A contactin-3 (human) that has been citrullinated on the residue at the position equivalent to Arg-565 of the amino acid sequence represented by UniProtKB:Q9P232. UniProtKB:Q9P232, Arg-565, MOD:00219.


name: Right Posterior Apical Transition Zone of Prostate

description: The region of the prostate that is located on the anatomical right side of the posterior portion of the apical division of the transition zone.


complement C4-A deaminated 5 (human)

A complement C4-A (human) that has been deaminated on the residue at the position equivalent to Asn-1347 of the amino acid sequence represented by UniProtKB:P0C0L4-1. Example: UniProtKB:P0C0L4-1, Asn-1347, MOD:00684.


5beta-Cholestane-3alpha,7alpha,24,26-tetrol with S-configuration at C-24.


Grade 3 Vision Decreased, CTCAE

description: Marked decrease in visual acuity (best corrected visual acuity worse than 20/40 or more than 3 lines of decreased vision from known baseline, up to 20/200)


Vacuum Cleaner Artifact

description: A magnetic field perturbation artifact that results in multiple high intensity rings.


name: outer membrane porin N, signal peptide removed form

description: An outer membrane porin N that has had the signal peptide removed.


name: phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha deaminated 1 (human)

description: A phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha (human) that has been deaminated on the residue at the position equivalent to Gln-1054 of the amino acid sequence represented by UniProtKB:O00443-1. Example: UniProtKB:O00443-1, Gln-1054, MOD:00685.


name: phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha

description: A protein that is a translation product of the human PIK3C2A gene or a 1:1 ortholog thereof.


name: P3C2A_MOUSE Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha (sprot)

description: A phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha that is encoded in the genome of mouse.


name: phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha isoform h2 (human)

description: A phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O00443-2.


name: phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha phosphorylated 1

description: A phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha that has been phosphorylated on the residue at the position equivalent to Ser-261 of the amino acid sequence represented by UniProtKB:Q61194. Example: UniProtKB:Q61194, Ser-261, MOD:00046.


name: phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha, initiator methionine removed form (human)

description: A phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha (human) that has had the initiator methionine removed. UniProtKB:O00443, 2-1686.


name: phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha isoform m2 (mouse)

description: A phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q61194-2.


name: P3C2A_HUMAN Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha (sprot)

description: A phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha that is encoded in the genome of human.


name: phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha phosphorylated 1 (mouse)

description: A phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha phosphorylated 1 in mouse. UniProtKB:Q61194, Ser-261, MOD:00046.


name: phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha, initiator methionine removed form

description: A phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha that has had the initiator methionine removed.


name: phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha isoform m1 (mouse)

description: A phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q61194-1.


name: phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha isoform h1 (human)

description: A phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O00443-1.


name: probable acylpyruvase FAHD2, mitochondrial isoform 1 (Arabidopsis thaliana)

description: A probable acylpyruvase FAHD2, mitochondrial (Arabidopsis thaliana) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9LUR3-1.


name: lysosome-associated membrane glycoprotein 1 N-glycosylated 26 (human)

description: A lysosome-associated membrane glycoprotein 1 (human) that has been N-glycosylated at the residue equivalent to Asn-249 of the amino acid sequence represented by UniProtKB:P11279-1, in which the glycan composition is represented by GlyTouCan:G40664HB. Example: UniProtKB:P11279-1, Asn-249, MOD:00160~GNO:G40664HB.


An alpha-L-Fucp-(1->3)-D-Galp in which the carbon bearing the anomeric hydroxy group has alpha configuration.


name: plasma protease C1 inhibitor N-glycosylated 14 (human)

description: A plasma protease C1 inhibitor (human) that has been N-glycosylated at the residue equivalent to Asn-25 of the amino acid sequence represented by UniProtKB:P05155-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P05155-1, Asn-25, MOD:00160~GNO:G43417UB.


name: UBL4A_RAT Ubiquitin-like protein 4A (sprot)

description: A ubiquitin-like protein 4A that is encoded in the genome of rat.


name: ubiquitin-like protein 4A isoform 1 (rat)

description: A ubiquitin-like protein 4A isoform 1 that is encoded in the genome of rat.


name: INT9_DROME Integrator complex subunit 9 (sprot)

description: An integrator complex subunit 9 that is encoded in the genome of fruit fly.


name: RL4_CLOBH Large ribosomal subunit protein uL4 (sprot)

description: A large ribosomal subunit protein uL4 that is encoded in the genome of Clostridium botulinum A str. Hall.


name: FIBIN_RAT Fin bud initiation factor homolog (sprot)

description: A fin bud initiation factor that is encoded in the genome of rat.


name: fin bud initiation factor homolog isoform 1 (rat)

description: A fin bud initiation factor isoform 1 that is encoded in the genome of rat.


mycophenolate mofetil

A carboxylic ester resulting from the formal condensation between the carboxylic acid group of mycophenolic acid and the hydroxy group of 2-(morpholin-4-yl)ethanol. In the liver, it is metabolised to mycophenolic acid, an immunosuppressant for which it is a prodrug. It is widely used to prevent tissue rejection following organ transplants as well as for the treatment of certain autoimmune diseases.


name: ADAL_MOUSE Adenosine deaminase-like protein (sprot)

description: An adenosine deaminase-like protein that is encoded in the genome of mouse.


name: adenosine deaminase-like protein isoform m2 (mouse)

description: An adenosine deaminase-like protein (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q80SY6-2.


name: adenosine deaminase-like protein isoform m3 (mouse)

description: An adenosine deaminase-like protein (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q80SY6-3.


name: adenosine deaminase-like protein isoform m4 (mouse)

description: An adenosine deaminase-like protein (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q80SY6-4.


name: adenosine deaminase-like protein isoform m1 (mouse)

description: An adenosine deaminase-like protein (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q80SY6-1.


FIGO Stage IIIB Ovarian Cancer

description: Ovarian cancer with macroscopic, extrapelvic, peritoneal metastasis equal or less than 2 cm +/- positive retroperitoneal lymph nodes. Includes extension to capsule of liver/spleen. (FIGO, 2014)


name: mannosyl-oligosaccharide alpha-1,2-mannosidase IA isoform K (fruit fly)

description: A mannosyl-oligosaccharide alpha-1,2-mannosidase IA (fruit fly) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P53624-2.


name: MA1A1_DROME Mannosyl-oligosaccharide alpha-1,2-mannosidase IA (sprot)

description: A protein that is a translation product of the alpha-Man-Ia gene in fruit fly.


name: mannosyl-oligosaccharide alpha-1,2-mannosidase IA isoform H (fruit fly)

description: A mannosyl-oligosaccharide alpha-1,2-mannosidase IA (fruit fly) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P53624-1.


name: chymotrypsin-like elastase family member 3B N-glycosylated 15 (human)

description: A chymotrypsin-like elastase family member 3B (human) that has been N-glycosylated at the residue equivalent to Asn-114 of the amino acid sequence represented by UniProtKB:P08861-1, in which the glycan structure is represented by GlyTouCan:G71367OV. Example: UniProtKB:P08861-1, Asn-114, MOD:00160~GNO:G71367OV.


name: BPIA2_RAT BPI fold-containing family A member 2 (sprot)

description: A BPI fold-containing family A member 2 that is encoded in the genome of rat.


name: BPI fold-containing family A member 2 isoform 1 (rat)

description: A BPI fold-containing family A member 2 isoform 1 that is encoded in the genome of rat.


name: BLK_MOUSE Tyrosine-protein kinase Blk (sprot)

description: A tyrosine-protein kinase BLK that is encoded in the genome of mouse.


name: ZN768_HUMAN Zinc finger protein 768 (sprot)

description: A zinc finger protein 768 that is encoded in the genome of human.


protein ZNF365 isoform 2 (human)

A ZNF365 gene translation product (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q70YC5-2.


name: mediator of RNA polymerase II transcription subunit 25 isoform 2 (Arabidopsis thaliana)

description: A mediator of RNA polymerase II transcription subunit 25 (Arabidopsis thaliana) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q7XYY2-2.


name: brain-specific angiogenesis inhibitor 1-associated protein 2 isoform h5 (human)

description: A brain-specific angiogenesis inhibitor 1-associated protein 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9UQB8-5.


name: CO7_HUMAN Complement component C7 (sprot)

description: A complement component C7 that is encoded in the genome of human.


complement component C7

A protein that is a translation product of the human C7 gene or a 1:1 ortholog thereof.


name: complement component C7, signal peptide removed form (human)

description: A complement component C7 (human) that has had the signal peptide removed. UniProtKB:P10643, 23-843.


name: complement component C7 N-glycosylated 1 (human)

description: A complement component C7 (human) that has been N-glycosylated at the residue equivalent to Asn-754 of the amino acid sequence represented by UniProtKB:P10643-1, in which the glycan composition is represented by GlyTouCan:G00912UN. Example: UniProtKB:P10643-1, Asn-754, MOD:00160~GNO:G00912UN.


name: complement component C7, signal peptide removed form

description: A complement component C7 that has had the signal peptide removed.


name: complement component C7 O-glycosylated 1 (human)

description: A complement component C7 (human) that has been O-glycosylated at the residue equivalent to Thr-696 of the amino acid sequence represented by UniProtKB:P10643-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P10643-1, Thr-696, MOD:00005~GNO:G43417UB.


name: leukocyte-associated immunoglobulin-like receptor 1 isoform m5 (mouse)

description: A leukocyte-associated immunoglobulin-like receptor 1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8BG84-5.


BCL9_DROME Protein BCL9 homolog (sprot)

A protein that is a translation product of the lgs gene in fruit fly.


name: RL26L_HUMAN Ribosomal protein uL24-like (sprot)

description: A ribosomal protein uL24-like that is encoded in the genome of human.


name: cysteine-rich receptor-like protein kinase 21 isoform 1 (Arabidopsis thaliana)

description: A cysteine-rich receptor-like protein kinase 21 (Arabidopsis thaliana) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q3E9X6-1.


name: CRK21_ARATH Cysteine-rich receptor-like protein kinase 21 (sprot)

description: A protein that is a translation product of the CRK21 gene in Arabidopsis thaliana.


name: serine/threonine-protein phosphatase 7 isoform 1 (Arabidopsis thaliana)

description: A serine/threonine-protein phosphatase 7 (Arabidopsis thaliana) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9FN02-1.


name: nitric oxide synthase 3 phosphorylated 1

description: A nitric oxide synthase 3 that has been phosphorylated on a residue equivalent to Ser-1176 of the amino acid sequence represented by UniProtKB:P70313. Example: UniProtKB:P70313, Ser-1176, MOD:00046.


name: nitric oxide synthase 3 phosphorylated 1 (mouse)

description: A nitric oxide synthase 3 phosphorylated 1 in mouse. UniProtKB:P70313, Ser-1176, MOD:00046.


name: NTAQ1_MOUSE Protein N-terminal glutamine amidohydrolase (sprot)

description: A protein N-terminal glutamine amidohydrolase that is encoded in the genome of mouse.


benzylpenicilloyl-benzylamine

A monocarboxylic acid amide formed between benzylpenicillin and benzylamine.


name: myristoylated alanine-rich C-kinase substrate phosphorylated 3 (human)

description: A myristoylated alanine-rich C-kinase substrate (human) that has been phosphorylated on the residue at the position equivalent to Ser-159 of the amino acid sequence represented by UniProtKB:P29966. UniProtKB:P29966, Ser-159, MOD:00046.


name: Grade 3 Stomach Intra-Operative Injury, CTCAE


name: serine protease FAM111B methylated 4 (human)

description: A serine protease FAM111B (human) that has been methylated on the residue at the position equivalent to Cys-451 of the amino acid sequence represented by UniProtKB:Q6SJ93-1. Example: UniProtKB:Q6SJ93-1, Cys-451, MOD:00660.


name: Recurrent T Acute Lymphoblastic Leukemia

description: The reemergence of T-acute lymphoblastic leukemia after a period of remission.