Gastric Cancer Clinical TNM Finding v8

description: A clinical finding about one or more characteristics of gastric cancer, following the rules of the TNM AJCC v8 classification system.


name: PSA Decline Greater than or Equal to 50 Percent

category: biolink:PhenotypicFeature biolink:DiseaseOrPhenotypicFeature biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing

description: A finding indicating that the blood concentration of prostate specific antigen in a subject's sample has decreased by at least 50 percent from the concentration recorded for a previous sample from that subject.


Childhood Gastric Carcinoma

category: biolink:Disease biolink:DiseaseOrPhenotypicFeature biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing

description: A rare carcinoma of the stomach that occurs during childhood.


name: Phlebitis Including Superficial Thrombosis, CTCAE


Breast Cancer pN3 TNM Finding v6

description: Breast cancer with metastasis in 10 or more axillary lymph nodes, or in infraclavicular lymph nodes, or in clinically apparent ipsilateral internal mammary lymph nodes in the presence of 1 or more positive axillary lymph nodes; or in more than 3 axillary lymph nodes with clinically negative microscopic metastasis in internal mammary lymph nodes; or in ipsilateral supraclavicular lymph nodes. (from AJCC 6th Ed.)


name: Grade 2 Esophagus Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


name: Grade 3 Superior Vena Cava Syndrome, CTCAE

description: Severe symptoms; multi-modality intervention indicated (e.g., anticoagulation, chemotherapy, radiation, stenting)


Stage IV Gallbladder Cancer AJCC v6

description: Stage IV includes: (Any T, Any N, M1).  M1: Distant metastasis. (AJCC 6th ed.)


name: Stage y-I Childhood Malignant Kidney Neoplasm Excluding Renal Cell Carcinoma by Toronto Guidelines v2, International Society of Pediatric Oncology (SIOP) Protocol

description: Tumor limited to kidney and completely resected. Renal capsule may be infiltrated by tumor, but tumor does not reach the outer surface. Tumor may protrude or bulge into the pelvic system or ureter but does not infiltrate. Vessel of renal sinus not involved. (Childhood cancer staging for population registries according to the Toronto Childhood Cancer Stage Guidelines - Version 2. Cancer Council Queensland and Cancer Australia: Brisbane, Australia; 2021.)


name: Drug Use Complicating Pregnancy, First Trimester

description: Evidence of drug use complicating pregnancy in the first trimester.


name: Grade 3 Extrapyramidal and Involuntary Movement and Restlessness, CTCAE


Native valve endocarditis

description: Endocarditis affecting a native valve of the heart.


Benign germ cell neoplasm

description: A germ cell tumor without evidence of atypia and metastatic potential.


Chromium Exposure

description: A finding indicating that an individual has been exposed to chromium or chromium-containing compounds.


Pleural Infection

description: An infectious process affecting the pleura.


name: Glottic Cancer Pathologic Regional Lymph Nodes TNM Finding v7

description: A pathologic finding about one or more characteristics of glottic cancer, following the rules of the TNM AJCC v7 classification system as they pertain to staging of regional lymph nodes.  Metastases at level VII are considered regional lymph node metastases. (from AJCC 7th Ed.)


Merkel Cell Carcinoma of Scalp and Neck

description: Evidence of Merkel cell carcinoma of scalp and neck.


name: Lower Gastrointestinal Tract Cancer TNM Finding v8

description: A finding about one or more characteristics of lower gastrointestinal tract cancer, following the rules of the TNM AJCC v8 classification system.


Stage II Uterine Corpus Cancer

description: Stage II includes: T2, N0, M0.  T2: Tumor invades stromal connective tissue of the cervix but does not extend beyond uterus.  Endocervical glandular involvement only should be considered as Stage I and not as Stage II.  N0: No regional lymph node metastasis. M0: No distant metastasis.  This staging applies to carcinomas and carcinosarcomas. (AJCC 7th ed.)


Esophageal Hodgkin Lymphoma

description: A very rare Hodgkin lymphoma that arises from the esophagus.


Refractory Vaginal Carcinoma

description: Vaginal carcinoma that does not respond to treatment.


name: Grade 4 Pancreas or Pancreatic Duct Stricture or Stenosis, CTCAE


RAD51 Gene Mutation Negative

description: A genetic finding indicating that RAD51 gene mutations have not been detected in a sample.


name: Bipolar Disorder, Current Episode Mixed, Unspecified

description: Evidence of bipolar disorder, current episode mixed.


Grade 2 Hypoxia, CTCAE

description: Decreased oxygen saturation with exercise (e.g., pulse oximeter <88%); intermittent supplemental oxygen


name: Melanoma in Situ of Unspecified Eyelid, Including Canthus

description: Evidence of melanoma in situ of unspecified eyelid including the canthus.


Verumontanum Mucosal Gland Hyperplasia

description: A benign microacinar proliferation occurring exclusively in the verumontanum and adjacent posterior urethra where the ejaculatory ducts and utricle empty into the urethra. Crystalloids and intraluminal mucin are usually absent, but; intraluminal corpora amylacea are often present. The lining epithelium typically consists of bland cuboidal to columnar luminal cells with underlying basal cells.


name: Unresectable Fallopian Tube Endometrioid Adenocarcinoma

description: Fallopian tube endometrioid adenocarcinoma that is not amenable to surgical resection.


name: Grade 2 Genitourinary Stoma Prolapse, CTCAE


name: Nontraumatic Subarachnoid Hemorrhage from Left Vertebral Artery

description: Evidence of nontraumatic subarachnoid hemorrhage from left vertebral artery.


name: Gastrointestinal Stromal Tumor Pathologic Distant Metastasis TNM Finding v7

description: A pathologic finding about one or more characteristics of gastrointestinal stromal tumor, following the rules of the TNM AJCC v7 classification system as they pertain to distant metastases.  There is no pathologic M0 for gastrointestinal stromal tumor. (from AJCC 7th Ed.)


name: Acute Myeloid Leukemia with t(1;17)(q42.3;q21.2); IRF2BP2-RARA

description: Acute myeloid leukemia with variant RARA rearrangement associated with t(1;17)(q42.3;q21.2) resulting in IRF2BP2-RARA fusion protein expression.


Salivary Gland Infection, CTCAE

description: A disorder characterized by an infectious process involving the salivary gland.


name: Cannabis Dependence with Other Cannabis-Induced Disorder

description: Evidence of cannabis dependence with other cannabis-induced disorder.


name: Grade 3 Meninges Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


description: Evidence of thyrotoxicosis factitia without thyrotoxic crisis or storm.


name: Pelvis Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils NOS, CTCAE


Vascular Access Graft Failure

description: Failure to achieve vascular access due to damage of the graft that was created for this purpose.


name: Grade 1 Muscle Weakness Right-Sided, CTCAE

description: Symptomatic; perceived by patient but not evident on physical exam


name: Monoplegia of Lower Limb following Non-Traumatic Intracerebral Hemorrhage Affecting Right Non-Dominant Side

description: Evidence of monoplegia of lower limb following non-traumatic intracerebral hemorrhage affecting right non-dominant side.


Anal Pain, CTCAE

description: A disorder characterized by a sensation of marked discomfort in the anal region.


name: Grade 1 Upper Extremity Artery Injury, CTCAE


name: Post-Immunization Arthropathy, Right Hip

description: Evidence of post-immunization arthropathy in the right hip.


Retinal Vascular Disorder, CTCAE

description: A disorder characterized by pathological retinal blood vessels that adversely affects vision.


name: Duodenum and Ampulla of Vater Neuroendocrine Tumor pN0 TNM Finding v8

description: Duodenum and ampulla of Vater neuroendocrine tumor without regional lymph node involvement. (from AJCC 8th Ed.)


name: Breast Cancer pN3c TNM Finding v6 and v7

description: Breast cancer with metastasis in ipsilateral supraclavicular lymph nodes. (from AJCC 6th and 7th Eds.)


name: Recurrent Adult Diffuse Large Cell Lymphoma

description: The reemergence of adult diffuse large cell lymphoma after a period of remission.


name: Grade 1 Transient Ischemic Attacks, CTCAE

description: Mild neurologic deficit with or without imaging confirmation


Benign Anal Granular Cell Tumor

description: A granular cell tumor that arises from the anus and is characterized by the absence of atypical or malignant cytological and architectural features, and absence of invasive features or metastatic potential.


Grade 4 Vision Decreased, CTCAE

description: Best corrected visual acuity of 20/200 or worse in the affected eye


Acquired Facial Nerve Palsy

description: A condition characterized by reduced or absent movement of the ipsilateral face as a consequence of an injury to the seventh cranial nerve that has occurred after birth.


name: Cerebral Infarction due to Thrombosis of Bilateral Carotid Arteries

description: Evidence of cerebral infarction due to a thrombosis of the bilateral carotid arteries.


name: Diffuse Large B-Cell Lymphoma, Intrathoracic Lymph Nodes

description: Evidence of diffuse large B-cell lymphoma, intrathoracic lymph nodes.


Grade 5 Pulmonary Edema, CTCAE

description: Death


Unresectable Fibrosarcoma

description: A fibrosarcoma that is not amenable to surgical resection.


Central line complication

description: A problem with a central venous access catheter or site of insertion.


name: Grade 4 Respiratory, Thoracic and Mediastinal Disorders - Other, Specify, CTCAE

description: Life-threatening consequences; urgent intervention indicated


Urinary Tract Pain, CTCAE

description: A disorder characterized by a sensation of marked discomfort in the urinary tract.


name: Atherosclerosis of Non-Autologous Biological Bypass Graft(s) of the Left Leg with Ulceration of Thigh

description: Evidence of atherosclerosis of non-autologous biological bypass graft(s) of the left leg with ulceration of thigh.


name: Beta Thalassemia Plus Structural Variants

description: A heterozygous state in which a person has a mutation in a beta globin allele causing beta thalassemia, together with other structural variants in the other allele.


Esthesioneurocytoma

description: A rare benign neuroectodermal tumor originating from olfactory receptor cells in the nasal cavity. Microscopically, it is characterized by the absence of malignant characteristics and the absence of rosettes formation.


Small Intestinal Mucositis, CTCAE

description: A disorder characterized by ulceration or inflammation of the mucous membrane of the small intestine.


Recurrent Primary Amyloidosis

description: The reemergence of primary amyloidosis after a period of remission.


Liver Cancer pT1 TNM Finding v7

description: Liver cancer with solitary tumor without vascular invasion. (from AJCC 7th Ed.)


Metastatic urothelial carcinoma

description: A carcinoma that arises from the urothelium and has spread from its original site of growth to another anatomic site.


Metastatic transitional cell carcinoma

description: A carcinoma that arises from transitional cells and has spread from its original site of growth to another anatomic site.


name: Type 1 diabetes mellitus with ketoacidosis, with coma

description: Evidence of type 1 diabetes mellitus with ketoacidosis with coma.


name: Grade 3 Radiation Recall Reaction (Dermatologic), CTCAE

description: Moist desquamation in areas other than skin folds and creases; bleeding induced by minor trauma or abrasion


Pulmonary Complication

description: Any pulmonary disorder occurring as a consequence of injury to the lungs.


name: Grade 2 Esophageal Varices Hemorrhage, CTCAE

description: Self-limited; intervention not indicated


Continued Complete Hematologic Response

description: Durable or long-term complete hematologic response. Time frames that define durability of complete hematologic response vary for different hematologic malignancies.


name: Diffuse Large B-Cell Lymphoma, Lymph Nodes of Inguinal Region and Lower Limb

description: Evidence of diffuse large B-cell lymphoma, lymph nodes of inguinal region and lower limb.


Asystole, CTCAE 5.0

description: A disorder characterized by a dysrhythmia without cardiac electrical activity. Typically, this is accompanied by cessation of the pumping function of the heart.


Grade 3 Apnea, CTCAE

description: Present; medical intervention indicated


name: Diffuse Large B-Cell Lymphoma, Intrapelvic Lymph Nodes

description: Evidence of diffuse large B-cell lymphoma, intrapelvic lymph nodes.


Neonatal Gastrointestinal Bleeding, AE

description: An adverse event in a newborn characterized by hemorrhage originating at any site located within the gastrointestinal tract.


name: Localized Childhood Malignant Bone Neoplasm by Toronto Guidelines v2

description: Tumor confined to the area of origin including the regional lymph nodes. (Childhood cancer staging for population registries according to the Toronto Childhood Cancer Stage Guidelines - Version 2. Cancer Council Queensland and Cancer Australia: Brisbane, Australia; 2021.)


name: Major Salivary Gland Cancer cM0 TNM Finding v8

description: Major salivary gland cancer without evidence of distant metastasis. (from AJCC 8th Ed.)


name: Malignant Neoplasm of Upper-Inner Quadrant of Unspecified Female Breast

description: Evidence of a malignant neoplasm of the upper-inner quadrant of unspecified female breast.


No Response to Treatment

description: No apparent pathologic and/or clinical changes resulting from treatment.


cocaine dependence with intoxication

description: Evidence of cocaine dependence with intoxication.


Gastric Cancer pN2 TNM Finding v7

description: Gastric cancer with metastasis in 3-6 regional lymph nodes. (from AJCC 7th Ed.)


name: Grade 2 Neuroendocrine ADH Secretion Abnormality, CTCAE


name: Grade 2 Blood Antidiuretic Hormone Abnormal, CTCAE

description: Symptomatic; medical intervention indicated


name: Nasopharyngeal Cancer pT0 TNM Finding v6 and v7

description: Nasopharyngeal cancer with no evidence of a primary tumor. (from AJCC 6th and 7th Eds.)


Solvent Exposure

description: Environmental, occupational, or consumer-based exposure to volatiles associated with production, handling and use of chemical solvents.


name: Lymphoblastic Diffuse Lymphoma, Extranodal and Solid Organ Sites

description: Evidence of lymphoblastic diffuse lymphoma in extranodal and solid organ sites.


name: Skin Squamous Cell Carcinoma or Other Skin Carcinomas pT0 TNM Finding v7

description: Skin squamous cell carcinoma or other skin carcinomas with no evidence of primary tumor. (from AJCC 7th Ed.)


name: Skin Squamous Cell Carcinoma or Other Skin Carcinomas pT2 TNM Finding v7

description: Skin squamous cell carcinoma or other skin carcinomas with a tumor size greater than 2 cm in greatest dimension or tumor of any size with two or more high-risk features.  High-risk features for the primary tumor staging are defined as follows: depth/invasion of more than 2 mm thickness; Clark level equal to or greater than IV; and perineural invasion.  Anatomic location: primary site ear and primary site non-hair-bearing lip.  Differentiation: poorly differentiated or undifferentiated. (from AJCC 7th Ed.)


Non-Neoplastic Peritoneal Disorder

description: A non-neoplastic disorder that affects the peritoneum. Representative examples include peritonitis and panniculitis.


name: Colorectal Neuroendocrine Tumor pTX TNM Finding v8

description: Colorectal neuroendocrine tumor in which the primary tumor cannot be assessed. (from AJCC 8th Ed.)


name: Lennox-Gastaut syndrome, not intractable, without status epilepticus

description: Evidence of Lennox-Gastaut syndrome without status epilepticus that responds to treatment.


name: Female Reproductive System Cancer TNM Finding v7

description: A finding about one or more characteristics of female reproductive system cancer, following the rules of the TNM AJCC v7 classification system.


Inherited neuropathies

description: A hereditary disorder that affects the sensory and/or motor nerves or the autonomic nerves.


Adrenal hemorrhage

description: Hemorrhage and necrosis of the adrenal gland tissue. Bilateral and extensive hemorrhage may lead to acute adrenal insufficiency, shock, and death.


name: Choroidal and Ciliary Body Melanoma pT3a TNM Finding v8

description: Choroidal and ciliary body melanoma, tumor size category 3 without ciliary body involvement and extraocular extension. (from AJCC 8th Ed.)


name: Carcinoma in Situ of Middle Ear and Respiratory System

description: Evidence of carcinoma in situ of the middle ear and respiratory system.


name: Left Basal Anterior Fibromuscular Stroma of Prostate

description: The portion of the fibromuscular stroma of the prostate that is located on the anatomical left side of the basal division of the anterior lobe.


Other specified disorders of brain

description: Evidence of other specified disorders of brain not specified elsewhere.


Tobacco Smoke Related Exposure

description: Environmental, occupational, or consumer-based exposure to airborne gases and particulates produced by direct or nearby use of a vaporized or combusted tobacco product.


name: Unspecified Atherosclerosis of Other Type of Bypass Graft(s) of the Extremities, Other Extremity

description: Evidence of unspecified atherosclerosis of other type of bypass graft(s) of the extremities in another extremity.


name: Other Psychoactive Substance Dependence with Psychoactive Substance-Induced Psychotic Disorder with Delusions

description: Evidence of other psychoactive substance dependence with psychoactive substance-induced psychotic disorder with delusions not specified elsewhere.


name: Grade 2 Thoracic Duct Intra-Operative Injury, CTCAE


name: Skin Reaction Secondary to Radiation Therapy


name: Intracranial Laceration Related to Birth

description: Tearing of the cerebral or cerebellar parenchyma or vessels of a newborn infant due to forces occurring during labor and delivery.


Grade 1 Hypernatremia, CTCAE

description: >ULN-150 mmol/L


name: Pathologic Stage IIIA Merkel Cell Carcinoma AJCC v8

description: Stage IIIA includes: (T1-4, N1a(sn) or N1a, M0); (T0, N1b, M0). T0: No evidence of primary tumor. T1: Maximum clinical tumor diameter equal to or less than 2 cm. T2: Maximum clinical tumor diameter more than 2 cm but equal to or less than 5 cm. T3: Maximum clinical tumor diameter more than 5 cm. T4: Primary tumor invades fascia, muscle, cartilage, or bone. N1a(sn): Clinically occult regional lymph node metastasis identified only by sentinel lymph node biopsy. N1a: Clinically occult regional lymph node metastasis following lymph node dissection. N1b: Clinically and/or radiologically detected regional lymph node metastasis, microscopically confirmed. M0: No distant metastasis detected on clinical and/or radiologic examination. (AJCC 8th ed.)


name: Grade 1 Pituitary Intra-Operative Injury, CTCAE


name: Juvenile Arthritis, Unspecified, Vertebrae

description: Evidence of unspecified juvenile arthritis in the vertebrae.


name: Grade 3 Pancreatic Enzymes Decreased, CTCAE

description: Sequelae of absorption deficiency


Grade 3 Esophagitis, CTCAE

description: Severely altered eating/swallowing; tube feeding, TPN, or hospitalization indicated


Fracture, CTCAE

description: A finding of traumatic injury to the bone in which the continuity of the bone is broken.


name: Glottic Cancer pN3 TNM Finding v6 and v7

description: Glottic cancer with metastasis in a lymph node, more than 6 cm in greatest dimension. (from AJCC 6th and 7th Eds.)


name: Grade 1 Intraoperative Musculoskeletal Injury, CTCAE

description: Primary repair of injured organ/structure indicated


Response in Non-Target Lesion

description: A qualitative or quantitative measurement of the response of a non-target lesion(s) to the therapy.


name: Juvenile Rheumatoid Arthritis with Systemic Onset, Multiple Sites

description: Evidence of juvenile rheumatoid arthritis with systemic onset in multiple sites.


Tumor Mass of the Extremity

description: A mass-forming benign or malignant neoplasm that affects a limb of the body.


Esophageal Neuroendocrine Tumor G3

description: A well differentiated, high grade neoplasm with neuroendocrine differentiation that arises from the esophagus. The Ki-67 index is higher than 20%.


name: Follicular Lymphoma Grade IIIb, Lymph Nodes of Axilla and Upper Limb

description: Evidence of follicular lymphoma grade IIIb in the lymph nodes of axilla and upper limb.


name: Carcinoma of the Lacrimal Gland pT4 TNM Finding v7

description: Carcinoma of the lacrimal gland with tumor invading periosteum or orbital bone or adjacent structures.  (from AJCC 7th Ed.)


name: Grade 2 Tendon Intra-Operative Injury, CTCAE


name: Grade 1 Female Genital Tract Fistula, CTCAE


Grade 1 Pleural Hemorrhage, CTCAE

description: Asymptomatic; mild hemorrhage confirmed by thoracentesis


Advanced Malignant Germ Cell Tumor

description: A malignant germ cell tumor that has spread extensively to other anatomic sites or is no longer responding to treatment.


Unresectable Endometrial Carcinoma

description: Endometrial carcinoma that is not amenable to surgical resection.


name: Gallbladder Cancer Clinical TNM Finding v6

description: A clinical finding about one or more characteristics of gallbladder cancer, following the rules of the TNM AJCC v6 classification system.


name: intraductal papillary-mucinous neoplasm of pancreas with moderate dysplasia

description: A non-invasive pancreatic intraductal papillary mucinous neoplasm characterized by the presence of neoplastic epithelial cells that exhibit nuclear stratification, loss of polarity, and crowding.  There is moderate nuclear hyperchromasia.


Systemic Sclerosis with Polyneuropathy

description: Evidence of systemic sclerosis with polyneuropathy.


name: Type 1 Diabetes Mellitus with Mild Nonproliferative Diabetic Retinopathy without Macular Edema

description: Evidence of type 1 diabetes mellitus with mild nonproliferative diabetic retinopathy without macular edema.


name: Rheumatoid nodule of subcutaneous tissue of right elbow

description: Evidence of rheumatoid nodule in the right elbow.


Aplastic anemia due to infection

description: Aplastic anemia caused by an infection.


Grade 3 Keratitis, CTCAE

description: Symptomatic with marked decrease in visual acuity (best corrected visual acuity worse than 20/40 or more than 3 lines of decreased vision from known baseline, up to 20/200); corneal ulcer; limiting self care ADL


Otitis Media, CTCAE

description: A disorder characterized by an infectious process involving the middle ear.


6/10 HLA Match

description: Degree of HLA match is 6/10 for HLA-A, -B, -C, -DRB1, and -DQB1 loci.


name: Subglottic Cancer Pathologic TNM Finding v7

description: A pathologic finding about one or more characteristics of subglottic cancer, following the rules of the TNM AJCC v7 classification system.  The pathologic staging requires the use of all information obtained in clinical staging and in histologic study of the surgically resected specimens.  (from AJCC 7th Ed.)


Sarcoma of the Orbit pT2 TNM Finding v7

description: Sarcoma of the orbit with tumor measuring more than 15 mm in greatest dimension without invasion of globe or bony wall.  (from AJCC 7th Ed.)


Grade 5 Neonatal Fever, AE

description: A febrile adverse event in a newborn which results in death.


name: Schizoaffective disorder, depressive type

description: Schizoaffective disorder with episodes of depression only.


Grade 2 Rectal Obstruction, CTCAE

description: Symptomatic; altered GI function; limiting instrumental ADL


name: Esophageal High Grade Intraepithelial Neoplasia

description: A lesion in which the architectural and cytologic abnormalities involve both the lower and the upper half of the esophageal mucosa.  It includes lesions termed moderate dysplasia, and carcinoma in situ (severe dysplasia).  (WHO, 2000)


Grade 4 Vasculitis, CTCAE

description: Life-threatening consequences; evidence of peripheral or visceral ischemia; urgent intervention indicated


name: Soft Tissue Sarcoma of the Trunk and Extremities pT1 TNM Finding v8

description: Soft tissue sarcoma of the trunk and extremities with tumor measuring 5 cm or less in greatest dimension. (from AJCC 8th Ed.)


Estrogen Receptor Status 2+

description: An immunohistochemical result of 2 for estrogen receptor expression that is considered intermediate for expression.


name: Advanced Primary Malignant Brain Neoplasm

description: A malignant neoplasm that arises from the brain and has spread extensively to other anatomic sites or is no longer responding to treatment.


name: Stage IIIB Fallopian Tube Cancer AJCC v7

description: Stage IIIB includes: T3b, N0, M0.  T3b: Macroscopic peritoneal metastasis outside the pelvis 2 cm or less in greatest dimension.  N0: No regional lymph node metastasis.  M0: No distant metastasis.  (AJCC 7th ed.)


Grade 3 Ileal Hemorrhage, CTCAE

description: Transfusion indicated; invasive intervention indicated; hospitalization


name: Grade 4 CNS Cerebrovascular Ischemia, CTCAE


Breast Cancer cT2 TNM Finding v6

description: Breast cancer with tumor size more than 2.0 cm, but not more than 5.0 cm in greatest dimension. (from AJCC 6th Ed.)


name: Pathologic Stage I Esophageal Adenocarcinoma AJCC v8

description: Stage I includes: IA: (T1a, N0, M0, G1); (T1a, N0, M0, GX); IB: (T1a, N0, M0, G2); (T1b, N0, M0, G1-2); (T1b, N0, M0, GX); IC: (T1, N0, M0, G3); (T2, N0, M0, G1-2). T1a: Tumor invades the lamina propria or muscularis mucosae. T1b: Tumor invades the submucosa. T1: Tumor invades the lamina propria, muscularis mucosae, or submucosa. T2: Tumor invades the muscularis propria. N0: No regional lymph node metastasis. M0: No distant metastasis. G1: Well-differentiated. GX: Grade cannot be assessed. G2: Moderately differentiated. G3: Poorly differentiated, undifferentiated. (AJCC 8th ed.)


Mediastinal Germ Cell Tumor TNM Finding

description: A TNM finding about one or more characteristics of a mediastinal germ cell tumor. This is not an official UICC TNM classification. (WHO Classification of Tumors of the Lung, Pleura, Thymus and Heart, 2015)


Neoplasm by Special Category

description: A neoplasm defined by its unique characteristic as they apply to clinical presentation and course, morphologic patterns, frequency, and/or age distribution.


Grade 3 Laryngeal Edema, CTCAE

description: Stridor; respiratory distress; hospitalization indicated


name: Grade 5 Peritoneal Cavity Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


name: Juvenile Myoclonic Epilepsy, not Intractable, without Status Epilepticus

description: Evidence of juvenile myoclonic epilepsy without status epilepticus that responds to treatment.


name: Upper Gastrointestinal Hemorrhage, CTCAE

description: A disorder characterized by bleeding from the upper gastrointestinal tract (oral cavity, pharynx, esophagus, and stomach).


name: Papillary, Follicular, Hurthle Cell, Poorly Differentiated, and Anaplastic Thyroid Carcinoma TNM Finding v8

description: A finding about one or more characteristics of papillary, follicular, Hurthle cell, poorly differentiated, and anaplastic (undifferentiated) thyroid carcinoma, following the rules of the TNM AJCC v8 classification system. Medullary thyroid cancers are staged according to the classification for thyroid-medullary. Thyroid lymphomas are staged according to the classification for Hodgkin and non-Hodgkin lymphoma. There are no AJCC staging systems for thyroid cancer arising from thyroglossal duct cyst and thyroid cancer in malignant struma ovarii. (from AJCC 8th Ed.)


name: Grade 3 Superior Vena Cava Vein Injury, CTCAE


name: Adenosarcoma Clinical Distant Metastasis TNM Finding v7

description: A clinical finding about one or more characteristics of adenosarcoma, following the rules of the TNM AJCC v7 classification system as they pertain to distant metastases.  (from AJCC 7th Ed.)


Vomiting, CTCAE

description: A disorder characterized by the reflexive act of ejecting the contents of the stomach through the mouth.


description: LDH more than 10 x N or hCG (mIu/ml) more than 50,000 or AFP (ng/ml) more than 10,000. N indicates the upper limit of normal for the LDH assay. (AJCC 7th ed.)


name: Grade 2 International Normalized Ratio of Prothrombin Time, CTCAE


Grade 4 Colonic Stenosis, CTCAE

description: Life-threatening consequences; urgent operative intervention indicated


name: Hemiplegia following Unspecified Cerebrovascular Disease Affecting Unspecified Side

description: Evidence of hemiplegia following unspecified cerebrovascular disease affecting unspecified side.


Grade 2 Hypoalbuminemia, CTCAE

description: <3-2 g/dL; <30-20 g/L


name: Left Posterolateral Apical Peripheral Zone of Prostate

description: The region of the prostate that is located on the anatomical left side of the posterolateral portion of the apical division of the peripheral zone.


Localized Gastric Carcinoma

description: A carcinoma that arises from the stomach and has not spread to other anatomic sites.


name: Type 2 Diabetes Mellitus with Diabetic Peripheral Angiopathy without Gangrene

description: Evidence of type 2 diabetes mellitus with diabetic peripheral angiopathy without gangrene.


Uterine Ligament Wolffian Tumor

description: An epithelial neoplasm of Wolffian (mesonephric) origin arising from a uterine ligament. Most tumors behave in a benign fashion.


name: Grade 5 Colon Infection with Unknown Absolute Neutrophil Count, CTCAE


Cervical Cancer cT3a TNM Finding v8

description: Cervical cancer involving the lower third of vagina but not extending to pelvic wall. (from AJCC 8th Ed.)


name: Small Intestine Cancer Clinical TNM Finding v7

description: A clinical finding about one or more characteristics of small intestine cancer, following the rules of the TNM AJCC v7 classification system.  Imaging studies such as CT and MRI play a major role in clinical staging.  Metastatic disease is assessed by routine chest films and chest CT.  Intraoperative assessment plays a role in clinical evaluation, especially when tumor cannot be resected. Metastatic involvement of the liver may be evaluated by intraoperative ultrasonography. (from AJCC 7th Ed.)


name: Esophagus and Esophagogastric Junction Cancer Pathologic Distant Metastasis TNM Finding v8

description: A pathologic finding about one or more characteristics of esophagus and esophagogastric junction cancer, following the rules of the TNM AJCC v8 classification system as they pertain to distant metastases.


Grade 1 Aspiration, CTCAE

description: Asymptomatic; clinical or diagnostic observations only; intervention not indicated


Transient Hyperinsulinism

description: Hyperinsulinism that resolves spontaneously. This is the most common cause of neonatal hypoglycemia.


Recurrent Malignant Solid Neoplasm

description: A malignant solid neoplasm that has recurred after a period of remission.


name: Post-Dysenteric Arthropathy, Unspecified Wrist

description: Evidence of post-dysenteric arthropathy in an unspecified wrist.


Chronic Decubitus

description: A longstanding lesion caused by death of tissue due to external pressure.


Sinusoidal hemangioma

description: A rare hemangioma occurring mainly in middle-aged adults. The most common location is in the trunk. The lesions are small, asymptomatic, and bluish. They are composed of irregular, dilated, congested thin-walled vascular channels with scant smooth muscle in a sinusoidal or sieve-like pattern. (WHO 2018)


Stage IB Cervical Cancer AJCC v9

description: Stage IB includes: T1b, N0, M0. T1b: Tumor with measured deepest invasion more than 5 mm (greater than FIGO stage IA); lesion limited to the cervix uteri with size measured by maximum tumor diameter. Note: The involvement of vascular/lymphatic spaces should not change the staging. The lateral extent of the lesion is no longer considered. N0: No regional lymph node metastasis. M0: No distant metastasis. (from AJCC 9th Ed.)


name: Febrile Neutropenia without Clinically or Microbiologically Documented Infection with Absolute Neutrophil Count Less Than 1 X 10e9 per Liter and Temperature Greater Than or Equal to 38 Point 5 Degrees Celsius, CTCAE


Grade 3 Atrial Fibrillation, CTCAE

description: Symptomatic, urgent intervention indicated; device (e.g., pacemaker); ablation; new onset


name: Grade 1 Cervical Spine Range of Motion, CTCAE


name: Hemoglobin Alpha Three Copies Deleted Genotype

description: A genetic finding indicating that one copy of chromosome 16 has only one functional copy of a hemoglobin alpha (HBA) gene and the other copy of has no functional HBA genes. This genotype is associated with hemoglobin H disease.


Incorrect Filter Applied Artifact

description: An image of reduced quality due to the collection or rejection of the wrong signal frequencies.


name: General Disorders and Administration Site Conditions - Other, Specify, CTCAE


Reiter's Disease, Unspecified Elbow

description: Evidence of Reiter's disease in an unspecified elbow.


name: Occlusion and Stenosis of Left Vertebral Artery

description: Evidence of occlusion and stenosis of left vertebral artery.


Verruca Plana

description: A wart characterized by the presence of flat-topped cutaneous papules. It is caused by human papillomavirus. It most commonly affects children and usually arises on the face, hands, and shins.


Macular Rash

description: An outbreak of small, flat, red spots on the skin.


name: Rheumatoid Lung Disease with Rheumatoid Arthritis of Right Elbow

description: Evidence of rheumatoid lung disease with rheumatoid arthritis of right elbow.


name: Major Salivary Gland Cancer pT4b TNM Finding v6

description: Major salivary gland cancer with tumor invading the skull base and/or pterygoid plates and/or encasing the carotid artery. (from AJCC 6th Ed.)


name: Stage IVB Cervical Cancer AJCC v6 and v7

description: Stage IVB includes: Any T, Any N, MI. M1: Distant metastasis. (AJCC 6th and 7th eds.)


Stage IIIC Gastric Cancer AJCC v7

description: Stage IIIC includes: (T4b, N2, M0); (T4b, N3, M0); (T4a, N3, M0).  T4a: Tumor invades serosa (visceral peritoneum).  T4b: Tumor invades adjacent structures. N2: Metastasis in 3-6 regional lymph nodes.  N3: Metastasis in seven or more regional lymph nodes. M0: No distant metastasis.  (AJCC 7th ed.)


Cutaneous Melanoma cM1d TNM Finding v8

description: Cutaneous melanoma with distant metastasis to CNS with or without M1a, M1b, or M1c sites of disease.  LDH level not recorded or unspecified. (from AJCC 8th Ed.)


Killing Pain

description: A sensation of extreme discomfort and anguish that is perceived as severe enough to cause one's death.


Recurrent Genetic Abnormalities Present

description: A laboratory test result indicating the presence of recurrent genetic abnormalities in cells.


name: Human Immunodeficiency Virus Infection Complicating Pregnancy, First Trimester

description: Evidence of human immunodeficiency virus infection complicating pregnancy in the first trimester.


name: Grade 2 Stoma Pulmonary Hemorrhage, CTCAE


Retinoblastoma pM1b TNM Finding v8

description: Retinoblastoma with pathological evidence of tumor in the cerebrospinal fluid or CNS parenchyma. (from AJCC 8th Ed.)


name: Other megaloblastic anemias, not elsewhere classified in ICD10CM

description: Evidence of other megaloblastic anemias, not elsewhere classified not specified elsewhere.


Enteropathic Arthropathies, Right Wrist

description: Evidence of enteropathic arthropathies in the right wrist.


name: Grade 2 Other Musculoskeletal and Soft Tissue, CTCAE


name: Metastatic Pancreatic Ductal Adenocarcinoma

description: An adenocarcinoma that arises from the exocrine pancreatic ducts and has metastasized to other anatomic sites.


Grade 1 Bullous Dermatitis, CTCAE

description: Asymptomatic; blisters covering <10% BSA


name: Grade 2 Glossopharyngeal Nerve Disorder, CTCAE

description: Moderate symptoms; limiting instrumental ADL


Hemoglobin Alpha Genotype Finding

description: A genetic finding indicating the genotype in a subject for the genes that encode hemoglobin subunit alpha, HBA1 and HBA2. Since the two HBA genes encode the same protein and are co-located on chromosome 16, the normal genotype is comprised of 2 maternal alpha genes and 2 paternal alpha genes (aa/aa).


name: Carcinoma of the Eyelid Pathologic Primary Tumor TNM Finding v7

description: A pathologic finding about one or more characteristics of carcinoma of the eyelid, following the rules of the TNM AJCC v7 classification system as they pertain to staging of the primary tumor.


Head and Neck Cancer pNX TNM Finding v8

description: Head and neck cancer in which the regional lymph nodes cannot be assessed.  (from AJCC 8th Ed.)


name: Homologous Recombination Repair Proficient

description: A finding indicating that a sample exhibits normal or near normal levels of homologous recombination DNA repair activity.


CTCAE v4 Grade 2

description: An adverse event for which only minimal, local, or noninvasive intervention (e.g. packing, cautery) is indicated; or that limits instrumental activities of daily living (ADLs, e.g., shopping, laundry, transportation, or ability to conduct finances).


name: Mucosal Melanoma of the Head and Neck Clinical TNM Finding v8

description: A clinical finding about one or more characteristics of mucosal melanoma of the head and neck, following the rules of the TNM AJCC v8 classification system.


Bilateral cataracts (disorder)

description: Partial or complete opacity of the crystalline lens of both eyes that decreases visual acuity and eventually results in blindness. Some cataracts appear in infancy or in childhood, but most develop in older individuals. (Sternberg Diagnostic Surgical Pathology, 3rd ed.)


name: Hematologic Malignancy-Associated Skin Squamous Cell Carcinoma

description: A squamous cell carcinoma that arises from the skin in a patient with a history of hematologic malignancy, usually non-Hodgkin lymphoma or chronic lymphocytic leukemia.


Marginal ulcer

description: An ulcer that develops in the jejunal mucosa close to the anastomosis site following a gastroenterostomy procedure.


name: Metastatic Carcinoma to the Uterine Cervix

description: A carcinoma that has spread to the cervix from another anatomic site.


Round Nodule

description: Nodule shape conforming to a roughly spherical shape, independent of spiculations.


Conjunctival foreign body

description: External material in or on the conjunctiva.


Gum Infection, CTCAE

description: A disorder characterized by an infectious process involving the gums.


description: A high grade poorly differentiated carcinoma arising from the digestive system.  It is composed of small or large neoplastic cells that express immunohistochemical evidence of neuroendocrine differentiation.  There is marked nuclear atypia, necrosis, and more than 20 mitoses per 10 HPF.


Harlequin Reaction

description: Transient blanching of the lower half of the body while in the lateral recumbent position, most commonly seen in premature or low birth weight infants.


name: Ampulla of Vater Cancer pT1b TNM Finding v8

description: Ampulla of Vater cancer with tumor invading beyond the sphincter of Oddi (perisphincteric invasion) and/or into the duodenal submucosa. (from AJCC 8th Ed.)


Low Glutathione Level

description: An indication that a lower than average level of glutathione was detected in a sample.


name: Grade 2 Intraoperative Endocrine Injury, CTCAE

description: Partial resection of injured organ/structure indicated


Nevus of Female Genitalia

description: A nevus that arises from the female genital organs. This category includes congenital nevus, acquired nevus, dysplastic nevus, blue nevus, and atypical melanocytic nevus of the genital type.


Pseudoporphyria

description: A drug-induced photodermatosis characterized by skin fragility, erythema, and the appearance of tense bullae, erosions and scarring in the absence of abnormalities in porphyrin metabolism.


name: Carcinoma in Situ of Skin of Left Lower Limb, Including Hip

description: Evidence of carcinoma in situ of the skin of left lower limb including the hip.


Increased Porphyrin

description: Increase in the amount of porphyrin.


name: Appendiceal Carcinoma cM1b TNM Finding v7

description: Appendiceal carcinoma with nonperitoneal metastasis. (from AJCC 7th Ed.)


name: Metabolic or Respiratory Acidosis, CTCAE


name: Lip and Oral Cavity Cancer pM0 TNM Finding

description: Lip and oral cavity cancer with no distant metastasis. (from AJCC 6th Ed.)


name: Faulty Instrument or Use of Instrument Artifact

description: An artifact resulting from the use of defective equipment or from improper use of equipment.


name: Fanconi Anemia Complementation Group Gene Mutation Negative

description: A genetic finding indicating that Fanconi anemia complementation group gene mutations have not been detected in a sample.


Grade 5 Hypertriglyceridemia, CTCAE

description: Death


Supraglottic Cancer pT4 TNM Finding v8

description: Supraglottic cancer with moderately advanced or very advanced disease. (from AJCC 8th Ed.)


name: Type 1 Diabetes Mellitus with Proliferative Diabetic Retinopathy with Macular Edema

description: Evidence of type 1 diabetes mellitus with proliferative diabetic retinopathy with macular edema.


name: Acute Myocardial Injury with Type I Myocardial Infarction Related to COVID-19

description: Acute myocardial injury with clinical presentation suggestive of type I myocardial infarction with detection of a rise or fall of cardiac troponin values with at least one value above the 99th percentile upper reference limit and with at least 1 of the following: 1. Symptoms of acute myocardial ischemia; 2. New ischemic ECG changes; 3. Development of pathological Q waves; 4. Imaging evidence of new loss of viable myocardium or new regional wall motion abnormality in a pattern consistent with an ischemic etiology; 5. Identification of a coronary thrombus by angiography including intracoronary imaging or by autopsy, occurring in a patient with probable or confirmed acute COVID-19.


description: Intraepithelial neoplasia of the penis or vulva. It usually presents as a solitary white or pink macule or plaque that may be slightly elevated. A background of long-standing lichen sclerosus is often present.


name: Grade 3 Upper Extremity Artery Intra-Operative Injury, CTCAE


Oral Pain

description: Painful sensation in the mouth, tongue, or lips.


name: Grade 3 Pharynx Mucositis or Stomatitis by Functional or Symptomatic Classification, CTCAE


Grade 5 Pancreas Infection, CTCAE

description: Death


name: Grade 5 Uterus Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


name: Appendiceal Carcinoma pN1a TNM Finding v8

description: Appendiceal carcinoma in which one regional lymph node is positive. (from AJCC 8th Ed.)


Hyperpnea

description: A clinical finding in which there is deeper breathing than normal. (ACC/AHA)


Acute Bacterial Prostatitis

description: An acute infection of the prostate gland caused by bacteria, most often Escherichia coli, Proteus mirabilis, Klebsiella, and Pseudomonas aeruginosa. Signs and symptoms include fever, lower back pain, urinary frequency, and painful urination.  The urinalysis reveals the presence of white cells.  Risk factors include intraprostatic ductal reflux, phimosis, urinary tract infections, and unprotected anal intercourse.


Abnormal Chest Radiograph

description: A history of having had an abnormal chest radiograph.


name: Localization-Related Symptomatic Epilepsy and Epileptic Syndromes with Simple Partial Seizures, Intractable, with Status Epilepticus

description: Evidence of localization-related symptomatic epilepsy and epileptic syndromes with simple partial seizures, with status epilepticus that does not respond optimally to treatment.


KMT2A Gene Rearrangement Negative

description: A genetic finding indicating that rearrangement of the KMT2A gene has not been detected in a sample.


Postoperative Hemorrhage, CTCAE

description: A disorder characterized by bleeding occurring after a surgical procedure.


Primary Site Response

description: The response at a primary site of a disease or condition to treatment.


Grade 3 Neck Edema, CTCAE

description: Generalized neck edema (e.g., difficulty in turning neck); limiting self care ADL


name: Carcinoma of the Lacrimal Gland TNM Finding v7

description: A finding about one or more characteristics of carcinoma of the lacrimal gland, following the rules of the TNM AJCC v7 classification system.  No stage grouping is presently recommended for carcinoma of the lacrimal gland.  (from AJCC 7th Ed.)


Grade 5 Bile Duct Stenosis, CTCAE

description: Death


name: Stage IIIC1 Uterine Corpus Cancer AJCC v8

description: Stage IIIC1 includes: T1-T3, N1/N1mi/N1a, M0. T1: Uterine corpus carcinoma or carcinosarcoma with tumor confined to the corpus uteri, including endocervical glandular involvement. T2: Uterine corpus carcinoma or carcinosarcoma with tumor invading the stromal connective tissue of the cervix but not extending beyond the uterus. Does not include endocervical glandular involvement. T3: Uterine corpus carcinoma or carcinosarcoma with tumor involving serosa, adnexa, vagina, or parametrium. N1: Regional lymph node metastasis to pelvic lymph nodes. N1mi: Regional lymph node metastasis (greater than 0.2 mm but nor greater than 2.0 mm in diameter) to pelvic lymph nodes. N1a: Regional lymph node metastasis (greater than 2.0 mm in diameter) to pelvic lymph nodes. M0: No distant metastasis. (from AJCC 8th Ed.)


name: Post-Immunization Arthropathy, Left Hand

description: Evidence of post-immunization arthropathy in the left hand.


pN3c TNM Finding

description: A pathologic regional lymph node TNM finding. The definition of pN3c finding depends on the particular type of cancer that it refers to; for example, for breast cancer, pN3c finding is defined as follows: cancer with metastases in ipsilateral supraclavicular lymph nodes. (from AJCC 8th Ed.)


N1mi TNM Finding

description: A regional lymph node TNM finding indicating the presence of micrometastases (greater than 0.2 mm and/or more than 200 cells, but none greater than 2.0 mm).


name: Breast Nipple and Areolar Deformity, CTCAE


Colorectal Cancer pTX TNM Finding v8

description: Colorectal cancer in which the primary tumor cannot be assessed. (from AJCC 8th Ed.)


name: Refractory Malignant Neoplasm of Multiple Primary Sites

description: Malignant neoplasm of multiple primary sites that is resistant to treatment.


Urethral Cancer pT0 TNM Finding v7

description: Urethral cancer with no evidence of primary tumor. (from AJCC 7th Ed.)


name: Grade 2 Vagina Stricture or Stenosis, CTCAE


name: Other Psychoactive Substance Abuse with Psychoactive Substance-Induced Sleep Disorder

description: Evidence of other psychoactive substance abuse with psychoactive substance-induced sleep disorder not specified elsewhere.


Urethral Melanoma

description: A rare melanoma that arises from the urethral mucosa.


name: Cerebral Infarction due to Embolism of Unspecified Cerebral Artery

description: Evidence of cerebral infarction due to an embolism of an unspecified cerebral artery.


name: Grade 3 Vein Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


name: Grade 2 Anus Intra-Operative Injury, CTCAE


name: Refractory Invasive Pulmonary Aspergillosis

description: Invasive pulmonary aspergillosis that is resistant to treatment.


Skin Nodulocystic Basal Cell Carcinoma

description: A nodular basal cell carcinoma composed of solid and cystic areas.


name: Facial Weakness following Cerebral Infarction

description: Evidence of facial weakness following cerebral infarction.


Thoracotomy Scar

description: Replacement of destroyed tissue by fibrous tissue due to a surgical procedure where an incision was made into the chest wall to the left or to the right of the midline.


Collapsed Lumen

description: A finding in which the walls of a tube or tubular organ have contorted or buckled into its cavity or channel.


Pharyngeal Stenosis, CTCAE

description: A disorder characterized by a narrowing of the pharyngeal airway.


name: Parathyroid Carcinoma pN1a TNM Finding v8

description: Metastasis to level VI (pretracheal, paratracheal, and prelaryngeal/Delphian lymph nodes), or superior mediastinal lymph nodes (level VII). (from AJCC 8th Ed.)


name: Cocaine Use, Unspecified with Cocaine-Induced Psychotic Disorder with Delusions

description: Evidence of cocaine use, unspecified with cocaine-induced psychotic disorder with delusions.


name: Esophagus and Esophagogastric Junction Cancer TNM Finding v7

description: A finding about one or more characteristics of esophagus and esophagogastric junction cancer, following the rules of the TNM AJCC v7 classification system.  Tumor location is simplified, and esophagogastric junction and proximal 5 cm of stomach are included in this classification.  Nonmucosal cancers are not included. (from AJCC 7th Ed.)


name: Other Specified Diabetes Mellitus with Stable Proliferative Diabetic Retinopathy, Bilateral

description: Evidence of other specified diabetes mellitus with stable proliferative diabetic retinopathy that is bilateral not specified elsewhere.


Lung Cancer pN0 TNM Finding v6 and v7

description: Lung cancer with no evidence of metastasis to regional lymph nodes. (from AJCC 6th and 7th Eds.)


ROS1 Gene Mutation Negative

description: A genetic finding indicating that ROS1 gene mutations have not been detected in a sample.


name: Grade 3 Pulmonary Fibrosis Radiographic Changes, CTCAE


Second Relapse

description: The reemergence of a disorder as diagnosed by clinical and/or laboratory evidence following two documented periods of remission.


name: Grade 5 Larynx Mucositis or Stomatitis by Clinical Examination Classification, CTCAE


P2 Hydronephrosis

description: Postnatal Hydronephrosis with the following clinical findings: 1) APRPD is greater than or equal to 15 mm, 2) the calyces may be dilated centrally and peripherally, 3) or a dilated ureter is visible, 4) the parenchymal thickness and appearance is normal, and 5) the bladder is normal. Cases in which there is peripheral calyceal dilation but the APRPD is less than 15 mm are classified as UTD P2. (Adapted from: Hiep T. Nguyen, Carol B. Benson, Bryann Bromley, Jeffrey B. Campbell, Jeanne Chow, Beverly Coleman, Christopher Cooper, Jude Crino, Kassa Darge, C.D. Anthony Herndon, Anthony O. Odibo, Michael J.G. Somers, Deborah R. Stein; Multidisciplinary consensus on the classification of prenatal and postnatal urinary tract dilation (UTD classification system); Pediatric Urology; December 2014 Volume 10, Issue 6, Pages 982-998)


name: Drug or Chemical Induced Diabetes Mellitus without Complications

description: Evidence of drug or chemical induced diabetes mellitus without complications.


name: Carcinoma in Situ of Liver, Gallbladder and Bilateral Ducts

description: Evidence of carcinoma in situ of the liver, gallbladder and bilateral ducts.


name: Prostatic Intraepithelial Neoplasia-Like Adenocarcinoma

description: A rare subtype of prostate acinar adenocarcinoma that morphologically resembles high-grade prostatic intraepithelial neoplasia. It is characterized by the presence of large malignant glands lined with pseudostratified epithelium. It is graded as Gleason score 3+3=6.


name: Resectable Malignant Female Reproductive System Neoplasm

description: A malignant female reproductive system neoplasm that is amenable to surgical resection.


Milk of Calcium

description: Densely calcified fluid, most often found radiographically in association with an obstruction.


Skin Atrophy, CTCAE 5.0

description: A disorder characterized by the degeneration and thinning of the epidermis and dermis.


name: Stage I Gastric Neuroendocrine Tumor AJCC v8

description: Stage I includes: T1, N0, M0. T1: Tumor invading the lamina propria or submucosa and is less than or equal to 1 cm in size. N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 8th ed.)


name: Carcinoma of the Conjunctiva cM0 TNM Finding v7

description: Carcinoma of the conjunctiva without evidence of distant metastasis. (from AJCC 7th Ed.)


name: Type 1 Diabetes Mellitus with Moderate Nonproliferative Diabetic Retinopathy with Macular Edema, Unspecified Eye

description: Evidence of type 1 diabetes mellitus with moderate nonproliferative diabetic retinopathy with macular edema in an unspecified eye.


name: Cervical Mesonephric Remnants and Hyperplasia

description: The presence of embryonic remnants of mesonephric ducts in the cervix and their benign hyperplastic proliferations.


8/10 HLA Match

description: Degree of HLA match is 8/10 for HLA-A, -B, -C, -DRB1, and -DQB1 loci.


Grade 3 Uveitis, CTCAE

description: Anterior uveitis with 3+ or greater cells; intermediate posterior or pan-uveitis


Glucagonoma, malignant

description: A glucagon-producing neuroendocrine tumor arising from the alpha cells of the pancreas.  It may be associated with necrolytic erythema migrans, diarrhea, diabetes, glossitis, weight loss, malabsorption, and anemia.  It displays vascular invasion and metastasizes to other anatomic sites.


name: Benign Osteoclastic Giant Cell-Rich Tumor of Bone

description: A giant cell tumor that arises from the bone and is characterized by the absence of local aggression and lack of metastatic potential.


Malignant neoplasm of vertebral column

description: Evidence of a malignant neoplasm of the vertebral column.


Neonatal rickets

description: Rickets that usually affects premature infants. Factors that contribute to the development of neonatal rickets include calcium, phosphorus, or calciferol deficiency. It manifests with spontaneous fractures, respiratory distress, and growth developmental delays.


name: Unresectable Pancreatic Ductal Adenocarcinoma

description: Pancreatic ductal adenocarcinoma that is not amenable to surgical resection.


Kawasaki Disease Symptom

description: The symptoms of Kawasaki disease that the patient had. (ACC/AHA)


name: Bipolar Disorder, Current Episode Depressed, Mild or Moderate Severity, Unspecified

description: Evidence of bipolar disorder, current episode depressed that is mild or moderate severity.


name: Grade 2 Ungual Infection with Unknown Absolute Neutrophil Count, CTCAE


T4c TNM Finding

description: A general term that refers to a TNM finding of a primary tumor with direct invasion of adjacent structures. The definition of T4c TNM finding depends on the specific type of cancer that it refers to; for example, for breast cancer it refers to a primary tumor that extends to the chest wall, not including the pectoralis muscle, and with edema (including peau d'orange) or ulceration of the skin of the breast or satellite skin nodules confined to the same breast; for ocular adnexal lymphoma it refers to a primary tumor that Involves the maxillofacial, ethmoidal, and/or frontal sinuses; for carcinoma of the conjunctiva it refers to a primary tumor that invades adjacent paranasal sinuses.


Chief Complaint is Present Weekly

description: The chief complaint is noted to occur at least once per week.


name: Drug or Chemical Induced Diabetes Mellitus with Proliferative Diabetic Retinopathy with Macular Edema, Bilateral

description: Evidence of drug or chemical induced diabetes mellitus with proliferative diabetic retinopathy with macular edema that is bilateral.


Immediately Life-Threatening Disorder

description: A disease finding indicating that there is reasonable likelihood that death will occur within a matter of months or premature death is likely without early treatment. (After 21 CFR 312.300)


name: Mechanical Complication of Biological Heart Valve Graft, Subsequent Encounter

description: Evidence of mechanical complication of biological heart valve graft, subsequent encounter.


Recurrent Acute Myeloid Leukemia

description: The reemergence of acute myeloid leukemia after a period of remission.


Host Tissue Response To Foreign Body

description: Growth of tissue in or around a foreign body as the body's antibody response to the foreign body.


Prostate Cancer TNM Finding v8

description: A finding about one or more characteristics of prostate cancer, following the rules of the TNM AJCC v8 classification system. This classification system applies to adenocarcinomas and squamous cell carcinomas of the prostate gland. It does not apply to sarcomas, urothelial cell carcinomas, and urothelial carcinoma of bladder involving prostate. (from AJCC 8th Ed.)


Less than Partial Clinical Response

description: A change towards improvement from the pretreatment baseline, but not meeting the criteria for complete response or partial response.


name: Grade 1 Thoracodorsal Nerve Intra-Operative Injury, CTCAE


Joints and Fascia Progression GvHD

description: A NIH joint and fascia score that has increased by 1 or more points or a decrease in P-ROM score by 1 point for any site.


name: Malignant Neoplasm of Short Bones of Unspecified Lower Limb

description: Evidence of a malignant neoplasm of the short bones of unspecified lower limb.


name: Mycosis Fungoides and Sezary Syndrome M1 TNM Finding v7

description: Visceral involvement (must have pathology confirmation and organ involved should be specified).  Note: for viscera, spleen and liver may be diagnosed by imaging criteria. (from AJCC 7th Ed.)


Recurrent Plasma Cell Neoplasm

description: The reemergence of a plasma cell neoplasm after a period of remission.


name: Follicular Lymphoma, Unspecified, Extranodal and Solid Organ Sites

description: Evidence of unspecified follicular lymphoma in the extranodal and solid organ sites.


Cervical Cancer pT1a TNM Finding v8

description: Invasive cervical carcinoma diagnosed only by microscopy. Stromal invasion with a maximum depth of 5.0 mm measured from the base of the epithelium and a horizontal spread of 7.0 mm or less. Vascular space involvement, venous or lymphatic, does not affect classification. (from AJCC 8th Ed.)


Prostate Paraganglioma

description: A paraganglioma that affects the prostate gland.


Anxiety, CTCAE 5.0

description: A disorder characterized by apprehension of danger and dread accompanied by restlessness, tension, tachycardia, and dyspnea unattached to a clearly identifiable stimulus.


name: Adenoma of the Retinal Pigment Epithelium

description: A benign neoplasm that arises from the retinal pigment epithelium. It consists of cords and tubules of variably pigmented proliferating retinal pigment epithelium cells, separated by fibrous stroma. Malignant transformation is rare. (WHO 2018)


Neonatal Herpes Simplex Infection

description: Infection in the first month of life caused by the Herpes simplex virus.


name: Ampulla of Vater Cancer pTis TNM Finding v7

description: Ampulla of Vater cancer with a finding of carcinoma in situ. (from AJCC 7th Ed.)


Grade 2 Esophageal Infection, CTCAE

description: Local intervention indicated (e.g., oral antibiotic, antifungal, antiviral)


TP53 Gene Mutation Negative

description: A genetic finding indicating that TP53 gene mutations have not been detected in a sample.


Nasopharyngeal Cancer TNM Finding v7

description: A finding about one or more characteristics of nasopharyngeal cancer, following the rules of the TNM AJCC v7 classification system.


name: Nasal Cavity and Ethmoid Sinus Cancer pN2a TNM Finding v6 and v7

description: Nasal cavity and ethmoid sinus cancer with metastasis to a single ipsilateral lymph node, more than 3 cm, but not more than 6 cm in greatest dimension. (from AJCC 6th and 7th Eds.)


name: Malignant Neoplasm of Long Bones of Unspecified Lower Limb

description: Evidence of a malignant neoplasm of the long bones of unspecified lower limb.


name: Grade 3 Other Allergy and Immunology, CTCAE


Non-Hereditary Lesion

description: A pathologic process that is not inherited in a familial pattern.


Grade 2 Movements Involuntary, CTCAE

description: Moderate symptoms; limiting instrumental ADL


name: Grade 4 Pelvis NOS Intra-Operative Injury, CTCAE


name: Low Grade Endometrial Endometrioid Adenocarcinoma

description: Endometrial endometrioid adenocarcinoma exhibiting 50% or less solid non-glandular, non-squamous growth.


Grade 1 Nail Ridging, CTCAE

description: Asymptomatic; clinical or diagnostic observations only; intervention not indicated


Measurable Residual Disease Persistence

description: Presence of residual disease based on pre-defined thresholds and quantifiable MRD positivity by laboratory techniques.


name: Exocrine Pancreatic Cancer Pathologic Distant Metastasis TNM Finding v6

description: A pathologic finding about one or more characteristics of exocrine pancreatic cancer, following the rules of the TNM AJCC v6 classification system as they pertain to distant metastases.


Lung Cancer pM0 TNM Finding

description: Lung cancer with no evidence of distant metastasis. (from AJCC 6th Ed.)


Penile Cancer cN3 TNM Finding v8

description: Penile cancer with palpable fixed inguinal nodal mass or pelvic lymphadenopathy unilateral or bilateral. (from AJCC 8th Ed.)


name: Other Malignant Neoplasm of Overlapping Sites of Skin

description: Evidence of other malignant neoplasm of overlapping sites of skin not specified elsewhere.


name: Cervical Cancer Clinical Regional Lymph Nodes TNM Finding v7

description: A clinical finding about one or more characteristics of cervical cancer, following the rules of the TNM AJCC v7 classification system as they pertain to staging of regional lymph nodes.


Neuroendocrine carcinoma of the bladder

description: A malignant, high grade neuroendocrine neoplasm that arises from the bladder. This category includes small cell and large cell neuroendocrine carcinoma.


Grade 3 Urostomy Obstruction, CTCAE

description: Altered organ function (e.g., sepsis or hydronephrosis, or renal dysfunction); elective operative intervention indicated


Grade 1 Urinary Retention, CTCAE

description: Urinary, suprapubic or intermittent catheter placement not indicated; able to void with some residual


name: Grade 1 Upper Extremity Vein Intra-Operative Injury, CTCAE


Drug Resistant Epilepsy

description: Epilepsy that is refractory to treatment.


Grade 1 Bronchopulmonary Dysplasia, AE

description: An adverse event in a newborn characterized by the need for supplemental oxygen at 28 days AND breathing room air at 36 weeks postmenstrual age (PMA) in infants born less than 32 weeks' gestation; breathing room air by 56 days postnatal age in infants born greater than 32 weeks' gestation; breathing room air at discharge. Note: For conversion of oxygen administered by different modalities to fraction of inspired oxygen (FiO2): see http://nicutools.org/MediCalcs/ActualO2.php3.


name: Stage IIIC Esophageal Adenocarcinoma AJCC v7

description: Stage IIIC includes: (T4a, N1-2, M0, Any G); (T4b, Any N, M0, Any G); (Any T, N3, M0, Any G).  T4a: Resectable tumor invading pleura, pericardium, or diaphragm. T4b: Unresectable tumor invading other adjacent structures, such as aorta, vertebral body, trachea, etc.  N1: Metastasis in 1-2 regional lymph nodes.  N2: Metastasis in 3-6 regional lymph nodes.  N3: Metastasis in seven or more regional lymph nodes.  M0: No distant metastasis.  (AJCC 7th ed.)


Recurrent WHO Grade 3 Glioma

description: The reemergence of a WHO grade III glioma after a period of remission.


Advanced Adenoid Cystic Carcinoma

description: Adenoid cystic carcinoma that has spread extensively to other anatomic sites or is no longer responding to treatment.


Gastric Cancer pN3 TNM Finding v6

description: Gastric cancer with evidence of metastasis in more than 15 regional lymph nodes. (from AJCC 6th Ed.)


name: Atherosclerosis of Unspecified Type of Bypass Graft(s) of Right Leg with Ulceration of Other Part of Foot

description: Evidence of atherosclerosis of unspecified type of bypass graft(s) of right leg with ulceration of other part of foot.


Breast Cancer cN2 TNM Finding v8

description: Breast cancer with metastases in ipsilateral level I, II axillary lymph nodes that are clinically fixed or matted; or in ipsilateral internal mammary nodes in the absence of axillary lymph node metastases. (from AJCC 8th Ed.)


name: Grade 5 Biliary Tree Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


name: Lacrimal Drainage System Lymphoepithelial Carcinoma

description: A rare nonkeratinizing squamous cell carcinoma that arises from the lacrimal sac or nasolacrimal duct. It is characterized by the presence of large cells with vesicular nuclei and prominent nucleoli, a syncytial growth pattern, and a lymphoplasmacytic infiltrate.


name: Atherosclerosis of Non-Biological Bypass Graft(s) of Left Leg with Ulceration of Heel and Midfoot

description: Evidence of atherosclerosis of non-biological bypass graft(s) of left leg with ulceration of heel and midfoot.


name: Other Reactive Arthropathies, Unspecified Hand

description: Evidence of other reactive arthropathies in an unspecified hand not specified elsewhere.


Thrombosis of abdominal aorta

description: Formation of blood clot in the lumen of the abdominal aorta. It may lead to severe abdominal pain and ischemic necrosis of the intestine.


Grade 2 Breast Infection, CTCAE

description: Local infection with moderate symptoms; oral intervention indicated (e.g., antibiotic, antifungal, or antiviral)


Stage IIIA Cervical Cancer FIGO 2018

description: Cervical carcinoma that involves the lower third of the vagina, with no extension to the pelvic wall. (FIGO 2018)


Facial Nerve Disorder, CTCAE

description: A disorder characterized by dysfunction of the facial nerve (seventh cranial nerve).


Grade 5 Bronchopulmonary Dysplasia, AE

description: A bronchopulmonary dysplasia adverse event in a newborn which results in death.


Acquired factor IX deficiency disease

description: An acquired coagulation disorder characterized by the partial or complete absence of factor IX activity in the blood.


Chief Complaint Present at Night

description: The chief complaint is noted to primarily occur between sunset and sunrise.


name: Grade 3 Mucosa Infection with Unknown Absolute Neutrophil Count, CTCAE


name: Mood Disorder due to Known Physiological Condition with Manic Features

description: Evidence of mood disorder due to known physiological condition with manic features.


name: Grade 3 Soft Tissue Infection NOS with Unknown Absolute Neutrophil Count, CTCAE


Life Threatening Adverse Event

description: An adverse event that has life-threatening consequences; for which urgent intervention is indicated; that puts the patient at risk of death at the time of the event if immediate intervention is not undertaken.


name: Other specified malignant neoplasm of skin of left lower eyelid, including canthus

description: Evidence of other specified malignant neoplasm of skin of left lower eyelid including the canthus not specified elsewhere.


Lung Cancer cM1a TNM Finding v7

description: Lung cancer with separate tumor nodule(s) in a contralateral lobe; tumor with pleural nodules or malignant pleural (or pericardial) effusion.  Most pleural (and pericardial) effusions with lung cancer are due to tumor.  In a few patients, however, multiple cytopathologic examinations of pleural (or pericardial) fluid) are negative for tumor, and the fluid is nonbloody and is not an exudate.  Where these elements and clinical judgment dictate that the effusion is not related to the tumor, the effusion should be excluded as a staging element and the patient should be classified as M0. (from AJCC 7th Ed.)


Burn, CTCAE

description: A finding of impaired integrity to the anatomic site of an adverse thermal reaction. Burns can be caused by exposure to chemicals, direct heat, electricity, flames and radiation. The extent of damage depends on the length and intensity of exposure and time until provision of treatment.


name: Refractory Fallopian Tube Adenocarcinoma

description: Fallopian tube adenocarcinoma that is resistant to treatment.


name: Rheumatoid Arthritis without Rheumatoid Factor, Unspecified Shoulder

description: Evidence of rheumatoid arthritis without rheumatoid factor in an unspecified shoulder.


name: Grade 3 Bone Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


name: Cerebral Infarction due to Embolism of Right Anterior Cerebral Artery

description: Evidence of cerebral infarction due to an embolism of the right anterior cerebral artery.


name: Grade 3 Pharynx Mucositis or Stomatitis by Clinical Examination Classification, CTCAE


name: IWG Hematologic Response Criteria for Treatment Response in Myeloproliferative Neoplasms

description: Criteria in inducing remission or improvement in myeloproliferative neoplasms according to the International Working Group-Myeloproliferative Neoplasms Research and Treatment (IWG-MRT).


name: Grade 4 Pancreatic Duct Intra-Operative Injury, CTCAE


name: Recurrent Pineal Parenchymal Cell Neoplasm

description: The reemergence of pineal parenchymal cell neoplasm after a period of remission.


Vulvar Cancer pT1 TNM Finding v8

description: Vulvar cancer with tumor confined to the vulva and/or perineum. Multifocal lesions should be designated as such. The largest lesion or the lesion with the greatest depth of invasion will be the target lesion identified to address the highest pT stage. Depth of invasion is defined as the measurement of the tumor from the epithelial-stromal junction of the adjacent most superficial dermal papilla to the deepest point of invasion. (from AJCC 8th Ed.)


Vagus Nerve Disorder, CTCAE

description: A disorder characterized by dysfunction of the vagus nerve (tenth cranial nerve).


name: Grade 3 Social Circumstances - Other, Specify, CTCAE

description: Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL


Grade 1 Gallbladder Pain, CTCAE

description: Mild pain


name: Indeterminate Extranodal Tumor Extension

description: A response that the extranodal tumor extension is undetermined.


Ureteric fistula

description: An abnormal communication between the ureter and another organ or anatomic site.


name: Grade 1 Anus Intra-Operative Injury, CTCAE


Grade 4 Stridor, CTCAE

description: Life-threatening airway compromise; urgent intervention indicated (e.g., tracheotomy or intubation)


Grade 2 Hepatitis B Reactivation, CTCAE

description: Moderate symptoms; medical intervention indicated


name: Grade 4 Carbon Monoxide Diffusion Capacity, CTCAE


Hemoglobin Response

description: An assessment of the disease response to therapy based on hemoglobin measurement.


Ophthalmologic Complication

description: Any eye disorder occurring as a consequence of injury to the eye.


Grade 1 Shingles, CTCAE

description: Localized, local intervention indicated


Cardiac Enzyme Elevation

description: An increase from the normal levels of cardiac enzymes measurement.


name: Type 2 Diabetes Mellitus with Mild Nonproliferative Diabetic Retinopathy without Macular Edema, Right Eye

description: Evidence of type 2 diabetes mellitus with mild nonproliferative diabetic retinopathy without macular edema in the right eye.


25-Hydroxyvitamin D Less than 66 ng/ml

description: A semiquantitative finding indicating that the concentration of 25-hydroxyvitamin D2 plus 25-hydroxyvitamin D3 is less than 66 ng/mL.


name: Grade 2 Meninges Intra-Operative Injury, CTCAE


Broad Ligament Serous Cystadenofibroma

description: A rare serous cystadenofibroma arising from the broad ligament.


Grade 2 Colonic Obstruction, CTCAE

description: Symptomatic; altered GI function


Grade 2 Amnesia, CTCAE

description: Moderate; short term memory loss; limiting instrumental ADL


Clinical Distant Metastasis TNM Finding

description: A clinical finding about one or more characteristics of a specific cancer, following the rules of the TNM classification system as they pertain to evaluating distant metastases.


name: Colon or Rectum Neuroendocrine Tumor pTX TNM Finding v7

description: Colon or rectum neuroendocrine tumor in which the primary tumor cannot be assessed. (from AJCC 7th Ed.)


name: Gastrointestinal Stromal Tumor cM0 TNM Finding v8

description: Gastrointestinal stromal tumor without distant metastasis. (from AJCC 8th Ed.)


FNCLCC Sarcoma Grade 3

description: A sarcoma with a total score of 6 or higher according to the FNCLCC guidelines.


name: Juvenile Rheumatoid Arthritis with Systemic Onset, Right Wrist

description: Evidence of juvenile rheumatoid arthritis with systemic onset in the right wrist.


name: Other Malignant Neoplasm Skin of Unspecified Upper Limb, Including Shoulder

description: Evidence of other malignant neoplasm skin of unspecified upper limb including the shoulder not specified elsewhere.


name: Other Specified Diabetes Mellitus with Diabetic Chronic Kidney Disease

description: Evidence of other specified diabetes mellitus with diabetic chronic kidney disease not specified elsewhere.


Grade 3 Arterial Injury, CTCAE

description: Severe symptoms; limiting self care ADL; repair or revision indicated


Plexiform Spindle Cell Melanocytoma

description: A subtype of WNT-activated deep penetrating/plexiform melanocytoma (nevus). It is characterized by the proliferation of neoplastic melanocytes in the upper dermis, forming a plexiform pattern.


Grade 3 Esophageal Ulcer, CTCAE

description: Severely altered GI function; TPN indicated; elective invasive intervention indicated; limiting self care ADL


name: Male Reproductive System Precancerous Condition

description: A premalignant pathologic process arising from an organ of the male reproductive system.  It is characterized by cellular atypia and/or dysplasia but does not show morphologic evidence of stromal invasion at the time of diagnosis.  Representative examples include prostatic intraepithelial neoplasia, giant condyloma acuminatum of the penis, and penile intraepithelial neoplasia.


Grade 1 Dermatitis Radiation, CTCAE

description: Faint erythema or dry desquamation


Global Response in Lymph Nodes

description: Criteria for the response to treatment in lymph nodes, as a component of global response.


Grade 1 Jejunal Ulcer, CTCAE

description: Asymptomatic; clinical or diagnostic observations only; intervention not indicated


Hepatic Failure, CTCAE

description: A disorder characterized by the inability of the liver to metabolize chemicals in the body. Laboratory test results reveal abnormal plasma levels of ammonia, bilirubin, lactic dehydrogenase, alkaline phosphatase, aminotransferase, and/or prolongation of prothrombin time (INR.) Drug-induced liever injury (DILI) as defined by Hy's Law.


name: Unresectable Ampulla of Vater Adenocarcinoma

description: Adenocarcinoma that arises from the ampulla of Vater and is not amenable to surgical resection.


name: Rheumatoid Heart Disease with Rheumatoid Arthritis of Right Ankle and Foot

description: Evidence of rheumatoid heart disease with rheumatoid arthritis of right ankle and foot.


Metastatic Bone Sarcoma

description: Bone sarcoma that has spread from the original site of growth to another anatomic site.


name: Hyperplasia of Brunner glands of duodenum

description: A rare hyperplastic lesion of Brunner's gland in the duodenum. Although it is usually asymptomatic and discovered incidentally during upper gastrointestinal endoscopy, it may cause hemorrhage.


name: Grade 1 Testis Intra-Operative Injury, CTCAE


Grade 2 Pleural Effusion, CTCAE

description: Symptomatic; intervention indicated (e.g., diuretics or therapeutic thoracentesis)


name: Drug or Chemical Induced Diabetes Mellitus with Stable Proliferative Diabetic Retinopathy, Unspecified Eye

description: Evidence of drug or chemical induced diabetes mellitus with stable proliferative diabetic retinopathy in an unspecified eye.


name: Mycosis Fungoides and Sezary Syndrome Primary Tumor-Skin TNM Finding v7

description: A finding about one or more characteristics of mycosis fungoides and Sezary syndrome, following the rules of the TNM AJCC v7 classification system as they pertain to staging of the primary tumor (skin).


name: Perihilar Bile Duct Cancer pT3 TNM Finding v8

description: Perihilar bile duct cancer with tumor invading unilateral branches of the portal vein or hepatic artery. (from AJCC 8th Ed.)


name: other specified leukemias, not having achieved remission

description: Evidence of other specified leukemias not having achieved remission not specified elsewhere.


name: Stage IVA Oral Cavity Verrucous Carcinoma


name: B-Cell Proliferation of Uncertain Malignant Potential

description: A B-cell lymphoproliferative disorder with uncertain malignant potential. The representative example of this category is lymphomatoid granulomatosis.


name: Vagina Infection with Unknown Absolute Neutrophil Count, CTCAE


Refractory Vulvar Carcinoma

description: Vulvar carcinoma that does not respond to treatment.


Cutaneous Melanoma pM1c TNM Finding v8

description: Cutaneous melanoma with distant metastasis to non-CNS visceral sites with or without M1a or M1b sites of disease.  LDH level not recorded or unspecified. (from AJCC 8th Ed.)


Grade 3 Cataract, CTCAE

description: Symptomatic with marked decrease in visual acuity (best corrected visual acuity worse than 20/40 or more than 3 lines of decreased vision from known baseline, up to 20/200); limiting self care ADL


name: Atherosclerosis of Native Arteries of Extremities with Intermittent Claudication, Other Extremity

description: Evidence of atherosclerosis of native arteries of extremities with intermittent claudication in another extremity.


Premature Delivery, CTCAE

description: A disorder characterized by delivery of a viable infant before the normal end of gestation. Typically, viability is achievable between the twentieth and thirty-seventh week of gestation.


Grade 3 Sleep Apnea, CTCAE

description: Oxygen desaturation; associated with pulmonary hypertension; medical intervention indicated; limiting self care ADL


name: Grade 1 Bronchopulmonary Hemorrhage NOS, CTCAE


Grade 5 Lymph Leakage, CTCAE

description: Death


name: Grade 2 Upper Aerodigestive NOS Intra-Operative Injury, CTCAE


name: Grade 3 Brain Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


Grade 3 Appendicitis, CTCAE

description: IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated


Non-Neoplastic Musculoskeletal Disorder

description: A non-neoplastic disorder that affects muscles and bones.


Sarcoma of the Orbit pN1 TNM Finding v7

description: Sarcoma of the orbit with regional lymph node metastasis. (from AJCC 7th Ed.)


name: Exocrine and Endocrine Pancreatic Cancer Clinical TNM Finding v7

description: A clinical finding about one or more characteristics of exocrine or endocrine pancreatic cancer, following the rules of the TNM AJCC v7 classification system.  Information necessary for the clinical staging of pancreatic cancer can be obtained from physical examination and three dimensional radiographic imaging studies, which include triphasic, contrast-enhanced multislice computed tomography or magnetic resonance imaging (MRI). (from AJCC 7th Ed.)


name: Esophagus and Esophagogastric Junction Cancer pN2 TNM Finding v8

description: Esophagus and esophagogastric junction cancer with metastasis in three to six regional lymph nodes. (from AJCC 8th Ed.)


Adrenal Cancer pT4 TNM Finding v7

description: Adrenal cancer with tumor of any size, with invasion of adjacent organs.  Adjacent organs include kidney, diaphragm, great vessels, pancreas, spleen, and liver. (from AJCC 7th Ed.)


name: Melanoma in situ of left eyelid, including canthus

description: Evidence of melanoma in situ of left eyelid including the canthus.


Thymic Tumor cM1 TNM Finding v8

description: Thymic tumor with pleural, pericardial, or distant metastasis. (from AJCC 8th Ed.)


name: Grade 3 Pharynx Obstruction and Stenosis, CTCAE


name: Grade 2 Blood Bilirubin Increased, CTCAE

description: >1.5-3.0 x ULN if baseline was normal; >1.5-3.0 x baseline if baseline was abnormal


lymphomatoid papulosis, type C

description: A variant of lymphomatoid papulosis characterized clinically by regressing skin papules, and morphologically by features resembling anaplastic large cell lymphoma.


description: Ovarian or testicular dysfunction associated with high levels of gonadotropins, that is present at birth.


name: Chronic Phase Chronic Myeloid Leukemia, Philadelphia Chromosome Positive, BCR-ABL1 Positive

description: A phase of chronic myeloid leukemia, Philadelphia chromosome positive, BCR-ABL1 positive in which the peripheral blood smear shows leukocytosis with neutrophils in different stages of maturation, less than 2% blasts, and normal or increased platelet count. Most patients have mild anemia. The bone marrow is hypercellular due to increased numbers of neutrophils and their precursors, and blasts usually account for fewer than 5% of the marrow cells. Megakaryocytes are smaller than normal and have hypolobated nuclei. The spleen is enlarged due to infiltration of the cords of the red pulp by granulocytes.


name: Thyroid Cancer pT4b Anaplastic Carcinoma TNM Finding v6

description: Anaplastic carcinoma extending beyond the capsule of the thyroid gland, which is surgically unresectable. (from AJCC 6th Ed.)


name: Recurrent Ampulla of Vater Adenocarcinoma

description: The reemergence of ampulla of Vater adenocarcinoma after a period of remission.


Maternal Weight Gain in Pregnancy

description: The last recorded maternal weight prior to birth minus the last recorded weight immediately prior to pregnancy. (reVITALize)


Congenital Cystic Hygroma

description: A congenital lymphatic malformation usually arising from the neck and characterized by cystic dilation of the lymphatic vessels.


Gastric Cancer pN1 TNM Finding v7

description: Gastric cancer with metastasis in 1-2 regional lymph nodes. (from AJCC 7th Ed.)


Adenocarcinoma endometrial metastatic

description: An adenocarcinoma which originated in the endometrium and has spread to another anatomic site.


Seminal Versicle Carcinoma

description: A carcinoma that arises from the seminal vesicle.


M1d TNM Finding

description: A TNM finding indicating the spread of cancer to distant anatomic sites. The definition of M1d TNM finding depends on the specific type of cancer to which it refers: for example, for cutaneous melanoma it indicates distant metastasis to CNS with or without M1a, M1b, or M1c sites of disease. LDH level not recorded or unspecified.


name: Refractory Acute Myeloid Leukemia Not Otherwise Specified

description: Acute myeloid leukemia not otherwise specified that does not respond to treatment.


name: IWG Hematologic Response Criteria for Treatment Response in Myelodysplastic Syndromes

description: Criteria in inducing remission or improvement in myelodysplastic syndromes according to the International Working Group-Myeloproliferative Neoplasms Research and Treatment (IWG-MRT).


name: Hepatocellular Carcinoma cM1 TNM Finding v8

description: Hepatocellular carcinoma with distant metastasis. (from AJCC 8th Ed.)


Merkel cell carcinoma of anal skin

description: Evidence of Merkel cell carcinoma of anal skin.


name: Recurrent Monomorphic Post-Transplant Lymphoproliferative Disorder

description: The reemergence of monomorphic post-transplant lymphoproliferative disorder after a period of remission.


name: Rheumatoid Polyneuropathy with Rheumatoid Arthritis of Left Elbow

description: Evidence of rheumatoid polyneuropathy with rheumatoid arthritis of left elbow.


name: Thyroid Cancer pN1 TNM Finding v6 and v7

description: Thyroid cancer with metastasis to regional lymph nodes. (from AJCC 6th and 7th Eds.)


Grade 5 Splenic Infection, CTCAE

description: Death


name: Monoplegia of Upper Limb Affecting Left Non-Dominant Side

description: Evidence of monoplegia of upper limb affecting left non-dominant side.


description: An exceedingly rare adenocarcinoma that arises from the endometrium and displays mesonephric differentiation. Some tumors are thought to derive from mesonephric duct (Wolffian duct) remnants. Others may have a Mullerian duct lineage.


Grade 1 Flatulence, CTCAE

description: Mild symptoms; intervention not indicated


Prostate Cancer cT3b TNM Finding v7

description: Prostate cancer invading seminal vesicle(s). (from AJCC 7th Ed.)


name: Cerebral Infarction due to Embolism of Left Posterior Cerebral Artery

description: Evidence of cerebral infarction due to an embolism of the left posterior cerebral artery.


BRAF Gene Alteration Negative

description: An indication that mutation, overexpression, fusion or rearrangement involving the BRAF gene has not been detected in a sample.


Stage IB Gastric Carcinoma

description: Stage IB includes: (T2, N0, M0); (T1, N1, M0).  T1: Tumor invades lamina propria, muscularis mucosae, or submucosa.  T2: Tumor invades the muscularis propria. N0: No regional lymph node metastasis.  N1: Metastasis in 1-2 regional lymph nodes. M0: No distant metastasis. (AJCC 7th ed.)


Appendicitis Perforated, CTCAE

description: A disorder characterized by acute inflammation to the vermiform appendix caused by a pathogenic agent with gangrenous changes resulting in the rupture of the appendiceal wall. The appendiceal wall rupture causes the release of inflammatory and bacterial contents from the appendiceal lumen into the abdominal cavity.


name: Grade 3 Prolapse of Intestinal Stoma, CTCAE

description: Severe symptoms; elective operative intervention indicated; limiting self care ADL


Non-Rheumatic Tricuspid Valve Stenosis

description: Evidence of non-rheumatic tricuspid valve stenosis.


name: Other specified diabetes mellitus without complications

description: Evidence of other specified diabetes mellitus without complication not specified elsewhere.


Female urinary-genital tract fistula

description: An abnormal connection between the urinary system and the genitals in a female.


name: Lung Cancer Pathologic Distant Metastasis TNM Finding v7

description: A pathologic finding about one or more characteristics of lung cancer, following the rules of the TNM AJCC v7 classification system as they pertain to distant metastases.  There is no pathologic M0 for lung cancer. (from AJCC 7th Ed.)


Grade 3 Lymph Node Pain, CTCAE

description: Severe pain; limiting self care ADL


description: An alveolar rhabdomyosarcoma characterized by the absence of chromosomal translocation t(1;13)(p36;q14) or t(2;13)(q35;q14) and therefore the absence of PAX7-FOXO1 or PAX3-FOXO1 gene fusion.


Primary Malignant Pelvic Neoplasm

description: A malignant neoplasm that arises from the organs and structures of the pelvis.


name: Grade 2 Colon Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


name: Malignant Neoplasm of Upper-Inner Quadrant of Unspecified Male Breast

description: Evidence of a malignant neoplasm of the upper-inner quadrant of unspecified male breast.


name: Unspecified Atherosclerosis of Non-Autologous Biological Bypass Graft(s) of the Extremities, Unspecified Extremity

description: Evidence of unspecified atherosclerosis of non-autologous biological bypass graft(s) of the extremities in an unspecified extremity.


Severe Cardiac Valve Regurgitation

description: Evidence of severe retrograde blood flow through the valve(s) of the heart. (ACC)


Bone Cancer TNM Finding v8

description: A finding about one or more characteristics of bone cancer, following the rules of the TNM AJCC v8 classification system. This classification system applies to osteosarcoma, chondrosarcoma, Ewing sarcoma, spindle cell sarcoma, hemangioendothelioma, angiosarcoma, fibrosarcoma/myofibroid sarcoma, chordoma, adamantinoma, and other cancers arising in the bone. It does not apply to primary malignant lymphoma of the bone and multiple myeloma. (from AJCC 8th Ed.)


name: FIGO Grade 1 Endometrial Mucinous Adenocarcinoma

description: A primary mucinous adenocarcinoma of the endometrium that contains equal to or less than 5% non-squamous solid areas.


Cancer Other

description: A finding indicating the presence of a malignancy that is not further specified or defined.


name: Vagina Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils, CTCAE


name: Grade 4 Gallbladder Intra-Operative Injury, CTCAE


Grade 5 Middle Ear Inflammation, CTCAE

description: Death


name: Drug or Chemical Induced Diabetes Mellitus with Proliferative Diabetic Retinopathy with Traction Retinal Detachment Involving the Macula, Right Eye

description: Evidence of drug or chemical induced diabetes mellitus with proliferative diabetic retinopathy with traction retinal detachment involving the macula in the right eye.


name: Mixed Cellularity Classic Hodgkin Lymphoma by Ann Arbor Stage

description: An anatomic stage for mixed cellularity classic Hodgkin lymphoma based on the Ann Arbor classification criteria.


Junctional Spitz Nevus

description: A Spitz nevus characterized by the presence of a junctional melanocytic component without involvement of the dermis.


Grade 4 Gallbladder Infection, CTCAE

description: Life-threatening consequences; urgent intervention indicated


Grade 1 Breast Atrophy, CTCAE

description: Minimal asymmetry; minimal atrophy


name: Chronic viral hepatitis B with hepatitis D

description: Evidence of chronic viral hepatitis B with delta-agent.


name: alcohol abuse with intoxication - uncomplicated

description: Evidence of alcohol abuse with intoxication, uncomplicated.


name: Nasal Cavity and Ethmoid Sinus Cancer Pathologic Primary Tumor TNM Finding v8

description: A pathologic finding about one or more characteristics of nasal cavity and ethmoid sinus cancer, following the rules of the TNM AJCC v8 classification system as they pertain to staging of the primary tumor.


Grade 3 Bladder Infection, CTCAE

description: IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated


Stage III Urethral Cancer AJCC v8

description: Stage III includes: (T1, N1, M0); (T2, N1, M0); (T3, N0, M0); (T3, N1, M0). T1: For male penile urethra and female urethra: Tumor invades subepithelial connective tissue. For prostatic urethra: Tumor invades urethral subepithelial connective tissue immediately underlying the urothelium. T2: For male penile urethra and female urethra: Tumor invades any of the following: corpus spongiosum, periurethral muscle. For prostatic urethra: Tumor invades the prostatic stroma surrounding ducts either by direct extension from the urothelial surface or by invasion from prostatic ducts. T3: For male penile urethra and female urethra: Tumor invades any of the following: corpus cavernosum, anterior vagina. For prostatic urethra: Tumor invades the periprostatic fat. N0: No regional lymph node metastasis. N1: Single regional lymph node metastasis in the inguinal region or true pelvis [perivesical, obturator, internal (hypogastric) and external iliac], or presacral lymph node. M0: No distant metastasis. (AJCC 8th ed.)


cocaine abuse with intoxication

description: Evidence of cocaine abuse with intoxication.


name: Grade 5 Scrotum Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils, CTCAE


Stage IIIA Appendix Carcinoma AJCC v8

description: Stage IIIA includes: (T1, N1, M0); (T2, N1, M0). T1: Tumor invades the submucosa (through the muscularis mucosa but not into the muscularis propria). T2: Tumor invades the muscularis propria. N1: One to three regional lymph nodes are positive (tumor in lymph node measuring 0.2 mm or more) or any number of tumor deposits is present, and all identifiable lymph nodes are negative. M0: No distant metastasis. (AJCC 8th ed.)


Non-Enhancing Lesion

description: Visibly abnormal tissue on a magnetic resonance image (MRI) or computed tomography (CT) that does not enhance with contrast and is not edema.


name: clear cell adenocarcinoma of gallbladder

description: A rare morphologic variant of gallbladder adenocarcinoma composed of malignant glandular epithelium with a predominance of glycogen rich clear cells.  The cells display hyperchromic nuclei and well-defined cytoplasmic borders.


name: Nervous System Disorders - Other, Specify, CTCAE


Chronic inflammation

description: An inflammatory process characterized by the presence of lymphocytes and plasma cells and the absence of polymorphonuclear neutrophils.


name: Other Psychoactive Substance Abuse with Withdrawal Delirium

description: Evidence of other psychoactive substance abuse with withdrawal delirium not specified elsewhere.


Fetal Neurodevelopmental Disorder

description: A fetal affliction that has a neurological basis and manifests as a developmental disability.


name: Jejunum and Ileum Neuroendocrine Tumor Clinical TNM Finding v8

description: A clinical finding about one or more characteristics of a jejunum and ileum neuroendocrine tumor, following the rules of the TNM AJCC v8 classification system.


Grade 3 Colonic Stenosis, CTCAE

description: Severely altered GI function; tube feeding or hospitalization indicated; elective operative intervention indicated


name: Partial occlusion of right retinal artery

description: Evidence of partial retinal artery occlusion in the right eye.


name: Grade 4 Cranial Nerve IX Motor Intra-Operative Injury, CTCAE


name: Grade 5 Neonatal Respiratory Insufficiency, AE

description: A respiratory insufficiency adverse event in a newborn which results in death.


name: Atherosclerosis of Non-Biological Bypass Graft(s) of the Extremities with Gangrene, Right Leg

description: Evidence of atherosclerosis of non-biological bypass graft(s) of the extremities with gangrene in the right leg.


Subglottic Cancer pT4a TNM Finding v7

description: Subglottic cancer with moderately advanced local disease.  Tumor invades cricoid or thyroid cartilage and/or invades tissues behind the larynx (e.g. trachea, soft tissues of neck including deep extrinsic muscles of the tongue, strap muscles, thyroid, or esophagus). (from AJCC 7th Ed.)


Miserable Pain

description: A sensation of discomfort or distress that renders an individual unable to find any happiness.


Grade 3 Bullous Dermatitis, CTCAE

description: Blisters covering >30% BSA; limiting self care ADL


Stage I Vulvar Cancer

description: Stage I includes: T1, N0, M0. T1: Invasive vulvar cancer confined to the vulva or perineum. N0: No regional lymph node metastasis.  M0: No distant metastasis. (AJCC 7th ed.)


Grade 5 Vagus Nerve Disorder, CTCAE

description: Death


name: Exhaled Carbon Monoxide Concentration Less than 10 ppm

description: An indication that the concentration of carbon monoxide (CO) in a sample of exhaled air is less than 10 ppm.


name: T-Cell Large Granular Lymphocyte Leukemia Expressing the T-Cell Receptor Gamma-Delta

description: An uncommon variant of T-cell large granular lymphocyte leukemia expressing the gamma-delta T-cell receptor. Approximately 60% of these cases are CD8-positive and the remainder are CD4/CD8-negative.


Conjunctival Carcinoma TNM Finding v8

description: A finding about one or more characteristics of conjunctival carcinoma, following the rules of the TNM AJCC v8 classification system. This classification system applies only to carcinoma of the conjunctiva. Other tumors of the conjunctiva, including secondary conjunctival tumors (e.g., intraocular tumors extending through the conjunctiva, such as uveal melanoma or uveal non-Hodgkin lymphoma, and orbital tumors extending into the conjunctiva, such as rhabdomyosarcoma), are not classified using this schema. Conjunctival lymphomas are staged according to the classification for ocular adnexal lymphoma and conjunctival melanomas are staged according to the classification for conjunctival melanoma. There is no proposal for anatomic stage and prognostic groups for conjunctival carcinoma. (from AJCC 8th Ed.)


Unresectable Low Grade Glioma

description: Low grade glioma that is not amenable to surgical removal.


name: Other Reactive Arthropathies, Unspecified Knee

description: Evidence of other reactive arthropathies in an unspecified knee not specified elsewhere.


name: Hemiplegia following Non-Traumatic Intracerebral Hemorrhage Affecting Left Dominant Side

description: Evidence of hemiplegia following non-traumatic intracerebral hemorrhage affecting left dominant side.


Gastrointestinal Perforation, CTCAE

description: An adverse event marked by rupture in the wall of a structure of the gastrointestinal system.


Stage III Bone Cancer AJCC v8

description: Stage III includes: T3, N0, M0, G2 or G3. T3: Discontinuous tumors in the primary bone site. N0: No regional lymph node metastasis. M0: No distant metastasis. G2: Moderately differentiated, high grade. G3: Poorly differentiated, high grade. (AJCC 8th ed.)


name: Grade 2 Colon Intra-Operative Injury, CTCAE


name: Radiating Chest Pain Along Right Middle Sternal Border

description: The location of the radiating chest pain is along the right middle sternal border.


name: Malignant Neoplasm of Unspecified Site of Unspecified Female Breast

description: Evidence of a malignant neoplasm of an unspecified site of an unspecified female breast.


Pancreatic Enzymes Decreased

description: A laboratory test result which indicates decreased levels of pancreatic enzymes in a biologic specimen.


name: Grade 1 Upper Extremity Intra-Operative Injury, CTCAE


Nevoid Melanoma

description: A rare variant of cutaneous melanoma occurring mostly in adults in their fifth decade. Morphologically it resembles an ordinary compound or dermal nevus.


KIT V559D Negative

description: A finding indicating that a mutation of the KIT gene encoding the amino acid substitution Val559Asp (V559D) in the  mast/stem cell growth factor receptor Kit protein has not been detected in a sample.


Skin Complete Response GvHD

description: An NIH skin score of 0 after previous GvHD involvement.


name: Sedative, Hypnotic or Anxiolytic Abuse with Sedative, Hypnotic or Anxiolytic-Induced Psychotic Disorder with Delusions

description: Evidence of sedative, hypnotic or anxiolytic abuse with sedative, hypnotic or anxiolytic-induced psychotic disorder with delusions.


name: Colon or Rectum Neuroendocrine Tumor Pathologic Regional Lymph Nodes TNM Finding v7

description: A pathologic finding about one or more characteristics of colon or rectum neuroendocrine tumor, following the rules of the TNM AJCC v7 classification system as they pertain to staging of regional lymph nodes.