name: transient receptor potential cation channel subfamily M member 2 isoform h2 (human)

description: A transient receptor potential cation channel subfamily M member 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O94759-2.


name: phosphatidylserine lipase ABHD16A isoform 1 (human)

description: A phosphatidylserine lipase ABHD16A isoform 1 that is encoded in the genome of human.


inborn organic aciduria

category: biolink:Disease biolink:DiseaseOrPhenotypicFeature biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing

description: An inherited disorder that affects the metabolism of any acidic compound containing carbon in a covalent linkage.


maple syrup urine disease

description: An autosomal recessive inherited disorder caused by mutations in the BCKDHA, BCKDHB, DBT, and DLD genes. It is characterized by a deficiency of branched-chain alpha-keto acid dehydrogenase complex, leading to accumulation of metabolites in the body fluids. The name of the disease derives from the sweet odor of the urine in infants, reminiscent of maple syrup. Signs and symptoms usually appear in infancy and include lethargy and developmental delays. If untreated, it may lead to seizures, coma, and death.


description: 3-methylcrotonyl-CoA carboxylase deficiency (3-MCCD) is an inherited disorder of leucine metabolism characterized by a highly variable clinical picture ranging from metabolic crisis in infancy to asymptomatic adults.


multiple carboxylase deficiency

description: Multiple carboxylase deficiency (MCD) is a term used to describe inborn errors of biotin metabolism characterized by reduced activities of biotin-dependent enzymes resulting in a wide spectrum of symptoms, including feeding difficulty, breathing difficulties, lethargy, seizures, skin rash, alopecia, and developmental delay.


name: methylmalonic aciduria and homocystinuria

description: An inborn error of vitamin B12 (cobalamin) metabolism characterized by megaloblastic anemia, lethargy, failure to thrive, developmental delay, intellectual deficit and seizures. There are four complementation classes of cobalamin defects (cblC, cblD, cblF and cblJ) that are responsible for methylmalonic acidemia - homocystinuria (methylmalonic acidemia - homocystinuria cblC, cblD cblF and cblJ).


name: vitamin B12-unresponsive methylmalonic acidemia type mut0

description: Vitamin B12-unresponsive methylmalonic acidemia type mut0 is an inborn error of metabolism characterized by recurrent ketoacidotic comas or transient vomiting, dehydration, hypotonia and intellectual deficit, which does not respond to administration of vitamin B12.


name: vitamin B12-unresponsive methylmalonic acidemia type mut-

description: Vitamin B12-unresponsive methylmalonic acidemia type mut- is an inborn error of metabolism characterized by recurrent ketoacidotic comas or transient vomiting, dehydration, hypotonia and intellectual deficit, which does not respond to administration of vitamin B12.


name: vitamin B12-responsive methylmalonic acidemia

description: Vitamin B12-responsive methylmalonic acidemia (MA) is an inborn error of vitamin B12 (cobalamin) metabolism characterized by recurrent ketoacidotic comas or transient vomiting, dehydration, hypotonia and intellectual deficit, which responds to vitamin B12. There are three types: cblA, cblB and cblD-variant 2 (cblDv2).


night blue

An iminium salt composed of 4-{(4-anilinonaphthalen-1-yl)[4-(diethylamino)phenyl]methylidene}-N,N-diethylcyclohexa-2,5-dien-1-iminium and chloride ions in a 1:1 ratio.


cytochrome b deaminated 1 (human)

A cytochrome b (human) that has been deaminated on the residue at the position equivalent to Asn-85 of the amino acid sequence represented by UniProtKB:P00156. UniProtKB:P00156, Asn-85, MOD:00684.


name: phosphatidate cytidylyltransferase, mitochondrial acetylated 1 (human)

description: A phosphatidate cytidylyltransferase, mitochondrial (human) that has been acetylated on the residue at the position equivalent to Lys-206 of the amino acid sequence represented by UniProtKB:Q96BW9-1. Example: UniProtKB:Q96BW9-1, Lys-206, MOD:00723.


name: hydroxymethylglutaryl-CoA synthase, mitochondrial, transit peptide removed form (human)

description: A hydroxymethylglutaryl-CoA synthase, mitochondrial (human) that has had the transit peptide removed. UniProtKB:P54868, 38-508.


name: sodium/potassium-transporting ATPase subunit alpha-4 methylated 2 (human)

description: A sodium/potassium-transporting ATPase subunit alpha-4 (human) that has been methylated on the residue at the position equivalent to Glu-295 of the amino acid sequence represented by UniProtKB:Q13733-1. Example: UniProtKB:Q13733-1, Glu-295, MOD:00713.


frizzled-4 isoform 1 (human)

A frizzled-4 isoform 1 that is encoded in the genome of human.


name: synaptotagmin-like protein 2 isoform h3 (human)

description: A synaptotagmin-like protein 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9HCH5-4.


name: solute carrier family 22 member 6 isoform h1 (human)

description: A solute carrier family 22 member 6 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q4U2R8-1.


name: E3 ubiquitin-protein ligase RAD18 methylated 1 (human)

description: An E3 ubiquitin-protein ligase RAD18 (human) that has been methylated on the residue at the position equivalent to Asn-394 of the amino acid sequence represented by UniProtKB:Q9NS91. UniProtKB:Q9NS91, Asn-394, MOD:00673.


name: exocyst complex component 2 methylated 2 (human)

description: An exocyst complex component 2 (human) that has been methylated on the residue at the position equivalent to Cys-719 of the amino acid sequence represented by UniProtKB:Q96KP1. UniProtKB:Q96KP1, Cys-719, MOD:00660.


name: acyl-coenzyme A synthetase ACSM1, mitochondrial isoform h2 (human)

description: An acyl-coenzyme A synthetase ACSM1, mitochondrial (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q08AH1-2.


name: galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3 isoform 1 (human)

description: A galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3 isoform 1 that is encoded in the genome of human.


gamma-aminooctyl-GTP

A nucleoside triphosphate analogue that is GTP in which one of the OH groups at the gamma-position of the triphosphate is replaced by an 8-aminooctylamino group.


name: G protein-activated inward rectifier potassium channel

description: An inwardly rectifying potassium channel protein that has core architecture consisting of an Inward rectifier potassium channel domain (Pfam:PF01007), which may be preceeded by an Inward rectifier potassium channel N-terminal domain (Pfam:PF08466).


name: inward rectifier potassium channel 13 isoform 1 (human)

description: An inward rectifier potassium channel 13 isoform 1 that is encoded in the genome of human.


name: ATP-sensitive inward rectifier potassium channel 11

description: A G protein-activated inward rectifier potassium channel that is a translation product of the human KCNJ11 gene or a 1:1 ortholog thereof.


name: ATP-sensitive inward rectifier potassium channel 11 isoform h2 (human)

description: An ATP-sensitive inward rectifier potassium channel 11 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q14654-2.


name: G protein-activated inward rectifier potassium channel 1 isoform 1 (human)

description: A G protein-activated inward rectifier potassium channel 1 isoform 1 that is encoded in the genome of human.


inward rectifier potassium channel 16

A G protein-activated inward rectifier potassium channel that is a translation product of the human KCNJ16 gene or a 1:1 ortholog thereof.


name: ATP-sensitive inward rectifier potassium channel 1

description: A G protein-activated inward rectifier potassium channel that is a translation product of the human KCNJ1 gene or a 1:1 ortholog thereof.


name: G protein-activated inward rectifier potassium channel 3 isoform 1 (human)

description: A G protein-activated inward rectifier potassium channel 3 isoform 1 that is encoded in the genome of human.


inward rectifier potassium channel 13

A G protein-activated inward rectifier potassium channel that is a translation product of the human KCNJ13 gene or a 1:1 ortholog thereof.


name: ATP-sensitive inward rectifier potassium channel 8

description: A G protein-activated inward rectifier potassium channel that is a translation product of the human KCNJ8 gene or a 1:1 ortholog thereof.


name: G protein-activated inward rectifier potassium channel 1

description: A G protein-activated inward rectifier potassium channel that is a translation product of the human KCNJ3 gene or a 1:1 ortholog thereof.


name: ATP-sensitive inward rectifier potassium channel 1 isoform h2 (human)

description: An ATP-sensitive inward rectifier potassium channel 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P48048-2.


name: ATP-sensitive inward rectifier potassium channel 10 isoform 1 (human)

description: An ATP-sensitive inward rectifier potassium channel 10 isoform 1 that is encoded in the genome of human.


inward rectifier potassium channel 4

A G protein-activated inward rectifier potassium channel that is a translation product of the human KCNJ4 gene or a 1:1 ortholog thereof.


inward rectifier potassium channel 2

A G protein-activated inward rectifier potassium channel that is a translation product of the human KCNJ2 gene or a 1:1 ortholog thereof.


name: ATP-sensitive inward rectifier potassium channel 11 isoform 1 (human)

description: An ATP-sensitive inward rectifier potassium channel 11 isoform 1 that is encoded in the genome of human.


name: ATP-sensitive inward rectifier potassium channel 8 isoform 1 (human)

description: An ATP-sensitive inward rectifier potassium channel 8 isoform 1 that is encoded in the genome of human.


name: ATP-sensitive inward rectifier potassium channel 1 isoform 1 (human)

description: An ATP-sensitive inward rectifier potassium channel 1 isoform 1 that is encoded in the genome of human.


name: ATP-sensitive inward rectifier potassium channel 1 isoform h3 (human)

description: An ATP-sensitive inward rectifier potassium channel 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P48048-3.


name: G protein-activated inward rectifier potassium channel 4

description: A G protein-activated inward rectifier potassium channel that is a translation product of the human KCNJ5 gene or a 1:1 ortholog thereof.


name: inward rectifier potassium channel 2 isoform 1 (human)

description: An inward rectifier potassium channel 2 isoform 1 that is encoded in the genome of human.


name: G protein-activated inward rectifier potassium channel 1 isoform h2 (human)

description: A G protein-activated inward rectifier potassium channel 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P48549-2.


name: ATP-sensitive inward rectifier potassium channel 14 citrullinated 1 (human)

description: An ATP-sensitive inward rectifier potassium channel 14 (human) that has been citrullinated on the residue at the position equivalent to Arg-233 of the amino acid sequence represented by UniProtKB:Q9UNX9. UniProtKB:Q9UNX9, Arg-233, MOD:00219.


name: G protein-activated inward rectifier potassium channel 4 isoform 1 (human)

description: A G protein-activated inward rectifier potassium channel 4 isoform 1 that is encoded in the genome of human.


name: ATP-sensitive inward rectifier potassium channel 15

description: A G protein-activated inward rectifier potassium channel that is a translation product of the human KCNJ15 gene or a 1:1 ortholog thereof.


name: ATP-sensitive inward rectifier potassium channel 10

description: A G protein-activated inward rectifier potassium channel that is a translation product of the human KCNJ10 gene or a 1:1 ortholog thereof.


name: ATP-sensitive inward rectifier potassium channel 15 isoform 1 (human)

description: An ATP-sensitive inward rectifier potassium channel 15 isoform 1 that is encoded in the genome of human.


name: G protein-activated inward rectifier potassium channel 3

description: A G protein-activated inward rectifier potassium channel that is a translation product of the human KCNJ9 gene or a 1:1 ortholog thereof.


name: inward rectifier potassium channel 4 phosphorylated 1 (human)

description: An inward rectifier potassium channel 4 (human) that has been phosphorylated at Tyr-234. UniProtKB:P48050, Tyr-234, MOD:00048.


name: G protein-activated inward rectifier potassium channel 2

description: A G protein-activated inward rectifier potassium channel that is a translation product of the human KCNJ6 gene or a 1:1 ortholog thereof.


name: ATP-sensitive inward rectifier potassium channel 12

description: A G protein-activated inward rectifier potassium channel that is a translation product of the human KCNJ12 gene or a 1:1 ortholog thereof.


name: ATP-sensitive inward rectifier potassium channel 14

description: A G protein-activated inward rectifier potassium channel that is a translation product of the human KCNJ14 gene or a 1:1 ortholog thereof.


name: inward rectifier potassium channel 2 phosphorylated 1 (human)

description: An inward rectifier potassium channel 2 (human) that has been phosphorylated on the residue at the position equivalent to Ser-165 of the amino acid sequence represented by UniProtKB:P63252. UniProtKB:P63252, Ser-165, MOD:00046.


name: inward rectifier potassium channel 13 isoform h2 (human)

description: An inward rectifier potassium channel 13 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O60928-2.


oxythiamine chloride

A organic chloride salt having oxythiamine as the counterion.


name: Ral guanine nucleotide dissociation stimulator isoform h2 (human)

description: A Ral guanine nucleotide dissociation stimulator (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q12967-2.


name: Ral guanine nucleotide dissociation stimulator

description: A protein that is a translation product of the human RALGDS gene or a 1:1 ortholog thereof.


name: Ral guanine nucleotide dissociation stimulator isoform h4 (human)

description: A Ral guanine nucleotide dissociation stimulator (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q12967-4.


name: Ral guanine nucleotide dissociation stimulator isoform h6 (human)

description: A Ral guanine nucleotide dissociation stimulator (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q12967-6.


name: Ral guanine nucleotide dissociation stimulator isoform h3 (human)

description: A Ral guanine nucleotide dissociation stimulator (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q12967-3.


name: Ral guanine nucleotide dissociation stimulator isoform h5 (human)

description: A Ral guanine nucleotide dissociation stimulator (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q12967-5.


name: Ral guanine nucleotide dissociation stimulator isoform h1 (human)

description: A Ral guanine nucleotide dissociation stimulator (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q12967-1.


name: cartilage oligomeric matrix protein N-glycosylated 2 (human)

description: A cartilage oligomeric matrix protein (human) that has been N-glycosylated at the residue equivalent to Asn-742 of the amino acid sequence represented by UniProtKB:P49747-1, in which the glycan composition is represented by GlyTouCan:G80920RR. Example: UniProtKB:P49747-1, Asn-742, MOD:00160~GNO:G80920RR.


name: solute carrier organic anion transporter family member 2A1 sequence variant C420F (human)

description: A solute carrier organic anion transporter family member 2A1 (human) that has a Phe residue at the position equivalent to Cys-420 of the amino acid sequence represented by UniProtKB:Q92959. UniProtKB:Q92959, Cys-420, CHEBI:29997.


name: solute carrier organic anion transporter family member 2A1

description: A solute carrier organic anion transporter family member that is a translation product of the human SLCO2A1 gene or a 1:1 ortholog thereof.


name: solute carrier organic anion transporter family member 2A1 sequence variant G222R (human)

description: A solute carrier organic anion transporter family member 2A1 (human) that has an Arg residue at the position equivalent to Gly-222 of the amino acid sequence represented by UniProtKB:Q92959. UniProtKB:Q92959, Gly-222, CHEBI:29952.


name: solute carrier organic anion transporter family member 2A1 sequence variant G255E (human)

description: A solute carrier organic anion transporter family member 2A1 (human) that has a Glu residue at the position equivalent to Gly-255 of the amino acid sequence represented by UniProtKB:Q92959. UniProtKB:Q92959, Gly-255, CHEBI:29972.


name: immunoglobulin heavy constant mu N-glycosylated 41 (human)

description: An immunoglobulin heavy constant mu (human) that has been N-glycosylated at the residue equivalent to Asn-272 of the amino acid sequence represented by UniProtKB:P01871-2, in which the glycan structure is represented by GlyTouCan:G65219TP. Example: UniProtKB:P01871-2, Asn-272, MOD:00160~GNO:G65219TP.


name: inositol 1,4,5-trisphosphate receptor type 3 deaminated 1 (human)

description: An inositol 1,4,5-trisphosphate receptor type 3 (human) that has been deaminated on the residue at the position equivalent to Asn-2567 of the amino acid sequence represented by UniProtKB:Q14573. UniProtKB:Q14573, Asn-2567, MOD:00684.


inherited cutis laxa

description: An instance of cutis laxa that is inherited.


name: pancreatic alpha-amylase isoform h1 (human)

description: A pancreatic alpha-amylase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P04746-1.


name: E3 ubiquitin-protein ligase Itchy homolog deaminated 5 (human)

description: An E3 ubiquitin-protein ligase Itchy homolog (human) that has been deaminated on the residue at the position equivalent to Asn-451 of the amino acid sequence represented by UniProtKB:Q96J02-1. Example: UniProtKB:Q96J02-1, Asn-451, MOD:00684.


name: transient receptor potential cation channel subfamily M member 1 phosphorylated 1 (human)

description: A transient receptor potential cation channel subfamily M member 1 (human) that has been phosphorylated on the residue at the position equivalent to Ser-995 of the amino acid sequence represented by UniProtKB:Q7Z4N2-1. Example: UniProtKB:Q7Z4N2-1, Ser-995, MOD:00046.


name: protein-glutamine gamma-glutamyltransferase E isoform 1 (human)

description: A protein-glutamine gamma-glutamyltransferase E isoform 1 that is encoded in the genome of human.


name: 5'(3')-deoxyribonucleotidase, cytosolic type isoform h2 (human)

description: A 5'(3')-deoxyribonucleotidase, cytosolic type (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8TCD5-2.


name: fermitin family homolog 2 isoform h2 (human)

description: A fermitin family homolog 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q96AC1-2.


calpain-10 isoform F (human)

A calpain-10 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9HC96-6.


name: mothers against decapentaplegic homolog 7 isoform h2 (human)

description: A mothers against decapentaplegic homolog 7 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O15105-2.


name: phospholipase A2 group XV, signal peptide removed form (human)

description: A phospholipase A2 group XV (human) that has had the signal peptide removed. Example: UniProtKB:Q8NCC3-1, 34-412.


name: 3-amino-5-methyl-4-[[3-(4-morpholinyl)propylamino]-oxomethyl]-2-thiophenecarboxylic acid ethyl ester


name: equilibrative nucleoside transporter 1 isoform h2 (human)

description: An equilibrative nucleoside transporter 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q99808-2.


name: DNA-directed RNA polymerase III subunit RPC2

description: A protein that is a translation product of the human POLR3B gene or a 1:1 ortholog thereof.


name: DNA-directed RNA polymerase III subunit RPC2 isoform h2 (human)

description: A DNA-directed RNA polymerase III subunit RPC2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9NW08-2.


name: DNA-directed RNA polymerase III subunit RPC2 isoform 1 (human)

description: A DNA-directed RNA polymerase III subunit RPC2 isoform 1 that is encoded in the genome of human.


name: DNA-directed RNA polymerase III subunit RPC2 citrullinated 1 (human)

description: A DNA-directed RNA polymerase III subunit RPC2 (human) that has been citrullinated on the residue at the position equivalent to Arg-1105 of the amino acid sequence represented by UniProtKB:Q9NW08-1. Example: UniProtKB:Q9NW08-1, Arg-1105, MOD:00219.


name: heat shock cognate 71 kDa protein cysteinylated 2 (human)

description: A heat shock cognate 71 kDa protein (human) that has been cysteinylated on the residue at the position equivalent to Cys-574 of the amino acid sequence represented by UniProtKB:P11142-1. Example: UniProtKB:P11142-1, Cys-574, MOD:00765.


name: methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial sequence variant MCCA R385S (human)

description: A methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial sequence variant (human) that has a Ser residue at the position equivalent to Arg-385 of the amino acid sequence represented by UniProtKB:Q96RQ3. UniProtKB:Q96RQ3, Arg-385, CHEBI:29999.


name: methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial sequence variant (human)

description: A methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial (human) that has at least one amino acid residue that differs from the corresponding residue found in another methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial (human) when such a difference arises as the result of genetic differences, i.e., different alleles of methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial (human). Operationally, this means the sequence representation of the methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial (human) has at least one amino acid residue that differs from the equivalent residue found in the sequence represented by UniProtKB:Q96RQ3-1.


name: methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial sequence variant MCCA A289V (human)

description: A methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial sequence variant (human) that has a Val residue at the position equivalent to Ala-289 of the amino acid sequence represented by UniProtKB:Q96RQ3. UniProtKB:Q96RQ3, Ala-289, CHEBI:30015.


name: methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial sequence variant MCCA L437P (human)

description: A methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial sequence variant (human) that has a Pro residue at the position equivalent to Leu-437 of the amino acid sequence represented by UniProtKB:Q96RQ3. UniProtKB:Q96RQ3, Leu-437, CHEBI:50342.


name: methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial sequence variant MCCA D532H (human)

description: A methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial sequence variant (human) that lacks the region encoded by exon 13 and shifts the reading frame due to the missense mutation D532H altering the splice site at the position equivalent to Asp-532 of the amino acid sequence represented by UniProtKB:Q96RQ3.


name: aggrecan core protein citrullinated 1 (human)

description: An aggrecan core protein (human) that has been citrullinated on the residue at the position equivalent to Arg-305 of the amino acid sequence represented by UniProtKB:P16112-1. Example: UniProtKB:P16112-1, Arg-305, MOD:00219.


name: importin subunit alpha-7 deaminated 2 (human)

description: An importin subunit alpha-7 (human) that has been deaminated on the residue at the position equivalent to Gln-45 of the amino acid sequence represented by UniProtKB:O60684. UniProtKB:O60684, Gln-45, MOD:00685.


name: ectonucleotide pyrophosphatase/phosphodiesterase family member 2 isoform h1 (human)

description: An ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q13822-1.


name: ectonucleotide pyrophosphatase/phosphodiesterase family member 2 isoform h3 (human)

description: An ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q13822-3.


cadherin-12 isoform 1 (human)

A cadherin-12 isoform 1 that is encoded in the genome of human.


name: serine/threonine-protein kinase ULK3 isoform 1 (human)

description: A serine/threonine-protein kinase ULK3 isoform 1 that is encoded in the genome of human.


vitamin B2

Any member of a group of vitamers that belong to the chemical structural class called flavins that exhibit biological activity against vitamin B2 deficiency. Symptoms associated with vitamin B2 deficiency include glossitis, seborrhea, angular stomaitis, cheilosis and photophobia. The vitamers include riboflavin and its phosphate derivatives (and includes their salt, ionised and hydrate forms).


name: interferon-induced, double-stranded RNA-activated protein kinase cysteinylated 1 (human)

description: An interferon-induced, double-stranded RNA-activated protein kinase (human) that has been cysteinylated on the residue at the position equivalent to Cys-485 of the amino acid sequence represented by UniProtKB:P19525-1. Example: UniProtKB:P19525-1, Cys-485, MOD:00765.


VILAZODONE HYDROCHLORIDE

A hydrochloride obtained by reaction of vilazodone with one equivalent of hydrochloric acid. Used for the treatment of major depressive disorder.


A 3-oxo Delta(4)-steroid that is testosterone carrying an additional oxo substituent at position 11.


interferon alpha-14

An interferon alpha that is a translation product of the human IFNA14 gene or a 1:1 ortholog thereof.


name: interferon alpha-14 N-glycosylated 2 (human)

description: An interferon alpha-14 (human) that has been N-glycosylated at the residue equivalent to Asn-95 of the amino acid sequence represented by UniProtKB:P01570-1, in which the glycan structure is represented by GlyTouCan:G75903TQ. Example: UniProtKB:P01570-1, Asn-95, MOD:00160~GNO:G75903TQ.


name: interferon alpha-14 N-glycosylated 1 (human)

description: An interferon alpha-14 (human) that has been N-glycosylated at the residue equivalent to Asn-95 of the amino acid sequence represented by UniProtKB:P01570-1, in which the glycan structure is represented by GlyTouCan:G07392QY. Example: UniProtKB:P01570-1, Asn-95, MOD:00160~GNO:G07392QY.


name: interferon alpha-14, signal peptide removed form (human)

description: An interferon alpha-14 (human) that has had the signal peptide removed. UniProtKB:P01570, 24-189.


name: CD14 molecule cleaved 2 GPI-anchored form (human)

description: A CD14 molecule cleaved 2 GPI-anchored form in human. UniProtKB:P08571, 20-345, Asn-345, MOD:00167.


name: 3-hydroxyacyl-CoA dehydrogenase type-2 isoform h2 (human)

description: A 3-hydroxyacyl-CoA dehydrogenase type-2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q99714-2.


name: 3-hydroxyacyl-CoA dehydrogenase type-2 isoform h1 (human)

description: A 3-hydroxyacyl-CoA dehydrogenase type-2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q99714-1.


name: 3-hydroxyacyl-CoA dehydrogenase type-2, initiator methionine removed form (human)

description: A 3-hydroxyacyl-CoA dehydrogenase type-2 (human) that has had the initiator methionine removed. UniProtKB:Q99714, 2-261.


name: DNA polymerase subunit gamma-1 deaminated 2 (human)

description: A DNA polymerase subunit gamma-1 (human) that has been deaminated on the residue at the position equivalent to Asn-1171 of the amino acid sequence represented by UniProtKB:P54098. UniProtKB:P54098, Asn-1171, MOD:00684.


name: DNA polymerase subunit gamma-1 deaminated 1 (human)

description: A DNA polymerase subunit gamma-1 (human) that has been deaminated on the residue at the position equivalent to Gln-262 of the amino acid sequence represented by UniProtKB:P54098. UniProtKB:P54098, Gln-262, MOD:00685.


name: cAMP-responsive element modulator isoform h11 (human)

description: A cAMP-responsive element modulator (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q03060-13.


NAD kinase cysteinylated 3 (human)

An NAD kinase (human) that has been cysteinylated on the residue at the position equivalent to Cys-69 of the amino acid sequence represented by UniProtKB:O95544-1. Example: UniProtKB:O95544-1, Cys-69, MOD:00765.


NAD kinase methylated 1 (human)

An NAD kinase (human) that has been methylated on the residue at the position equivalent to Cys-349 of the amino acid sequence represented by UniProtKB:O95544-1. Example: UniProtKB:O95544-1, Cys-349, MOD:00660.


NAD kinase cysteinylated 1 (human)

An NAD kinase (human) that has been cysteinylated on the residue at the position equivalent to Cys-180 of the amino acid sequence represented by UniProtKB:O95544-1. Example: UniProtKB:O95544-1, Cys-180, MOD:00765.


NAD kinase cysteinylated 2 (human)

An NAD kinase (human) that has been cysteinylated on the residue at the position equivalent to Cys-402 of the amino acid sequence represented by UniProtKB:O95544-1. Example: UniProtKB:O95544-1, Cys-402, MOD:00765.


NAD kinase isoform h1 (human)

An NAD kinase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O95544-1.


NAD kinase isoform h2 (human)

An NAD kinase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O95544-2.


NAD kinase deaminated 1 (human)

An NAD kinase (human) that has been deaminated on the residue at the position equivalent to Gln-195 of the amino acid sequence represented by UniProtKB:O95544-1. Example: UniProtKB:O95544-1, Gln-195, MOD:00685.


name: U5 small nuclear ribonucleoprotein 200 kDa helicase cysteinylated 4 (human)

description: A U5 small nuclear ribonucleoprotein 200 kDa helicase (human) that has been cysteinylated on the residue at the position equivalent to Cys-1278 of the amino acid sequence represented by UniProtKB:O75643-1. Example: UniProtKB:O75643-1, Cys-1278, MOD:00765.


name: DNA replication licensing factor MCM4 methylated 2 (human)

description: A DNA replication licensing factor MCM4 (human) that has been methylated on the residue at the position equivalent to Cys-306 of the amino acid sequence represented by UniProtKB:P33991. UniProtKB:P33991, Cys-306, MOD:00660.


name: DNA replication licensing factor MCM4 cysteinylated 2 (human)

description: A DNA replication licensing factor MCM4 (human) that has been cysteinylated on the residue at the position equivalent to Cys-306 of the amino acid sequence represented by UniProtKB:P33991. UniProtKB:P33991, Cys-306, MOD:00765.


name: DNA replication licensing factor MCM4 deaminated 2 (human)

description: A DNA replication licensing factor MCM4 (human) that has been deaminated on the residue at the position equivalent to Gln-257 of the amino acid sequence represented by UniProtKB:P33991. UniProtKB:P33991, Gln-257, MOD:00685.


name: DNA replication licensing factor MCM4 deaminated 1 (human)

description: A DNA replication licensing factor MCM4 (human) that has been deaminated on the residue at the position equivalent to Gln-259 of the amino acid sequence represented by UniProtKB:P33991. UniProtKB:P33991, Gln-259, MOD:00685.


name: DNA replication licensing factor MCM4 methylated 3 (human)

description: A DNA replication licensing factor MCM4 (human) that has been methylated on the residue at the position equivalent to Cys-328 of the amino acid sequence represented by UniProtKB:P33991. UniProtKB:P33991, Cys-328, MOD:00660.


name: DNA replication licensing factor MCM4 methylated 4 (human)

description: A DNA replication licensing factor MCM4 (human) that has been methylated on the residue at the position equivalent to Cys-309 of the amino acid sequence represented by UniProtKB:P33991. UniProtKB:P33991, Cys-309, MOD:00660.


name: DNA replication licensing factor MCM4 cysteinylated 1 (human)

description: A DNA replication licensing factor MCM4 (human) that has been cysteinylated on the residue at the position equivalent to Cys-328 of the amino acid sequence represented by UniProtKB:P33991. UniProtKB:P33991, Cys-328, MOD:00765.


name: DNA replication licensing factor MCM4 methylated 1 (human)

description: A DNA replication licensing factor MCM4 (human) that has been methylated on the residue at the position equivalent to Cys-162 of the amino acid sequence represented by UniProtKB:P33991. UniProtKB:P33991, Cys-162, MOD:00660.


name: DNA replication licensing factor MCM4, initiator methionine removed form (human)

description: A DNA replication licensing factor MCM4 (human) that has had the initiator methionine removed. UniProtKB:P33991, 2-863.


name: acyl-coenzyme A thioesterase 2, mitochondrial isoform h2 (human)

description: An acyl-coenzyme A thioesterase 2, mitochondrial (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P49753-2.


name: acyl-coenzyme A thioesterase 2, mitochondrial isoform h1 (human)

description: An acyl-coenzyme A thioesterase 2, mitochondrial (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P49753-1.


name: Rho GDP-dissociation inhibitor 2 deaminated 1 (human)

description: A Rho GDP-dissociation inhibitor 2 (human) that has been deaminated on the residue at the position equivalent to Asn-23 of the amino acid sequence represented by UniProtKB:P52566. UniProtKB:P52566, Asn-23, MOD:00684.


name: nuclear factor of activated T-cells, cytoplasmic 4 isoform h19 (human)

description: A nuclear factor of activated T-cells, cytoplasmic 4 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q14934-19.


name: E3 SUMO-protein ligase RanBP2 glutathionylated 2 (human)

description: An E3 SUMO-protein ligase RanBP2 (human) that has been glutathionylated on the residue at the position equivalent to Cys-319 of the amino acid sequence represented by UniProtKB:P49792. UniProtKB:P49792, Cys-319, MOD:00234.


name: ALK tyrosine kinase receptor sequence variant G881D, signal peptide removed form (human)

description: An ALK tyrosine kinase receptor (human) that has an Asp residue at the position equivalent to Gly-881 of the amino acid sequence represented by UniProtKB:Q9UM73 and that has had the signal peptide removed. UniProtKB:Q9UM73, 19-1620, Gly-881, CHEBI:29958.


name: voltage-gated potassium channel subunit beta-2 phosphorylated 1 (human)

description: A voltage-gated potassium channel subunit beta-2 (human) that has been phosphorylated on the residue at the position equivalent to Ser-266 of the amino acid sequence represented by UniProtKB:Q13303-1. Example: UniProtKB:Q13303-1, Ser-266, MOD:00046.


name: ribosomal oxygenase 2 methylated 1 (human)

description: A ribosomal oxygenase 2 (human) that has been methylated on the residue at the position equivalent to Cys-156 of the amino acid sequence represented by UniProtKB:Q8IUF8-1. Example: UniProtKB:Q8IUF8-1, Cys-156, MOD:00660.


isoprenoid

Any lipid formally derived from isoprene (2-methylbuta-1,3-diene), the skeleton of which can generally be discerned in repeated occurrence in the molecule. The skeleton of isoprenoids may differ from strict additivity of isoprene units by loss or shift of a fragment, commonly a methyl group. The class includes both hydrocarbons and oxygenated derivatives.


A 3beta-hydroxy-4alpha-formyl-4beta-methylsteroid that is 24-methylene-9beta-9,19-cyclolanostane-3beta,28-diol in which the hydroxy group at position 28 has been oxidised to give the corresponding aldehyde.


GINSENOSIDE RB3

A ginsenoside found in Panax species that is dammarane which is substituted by hydroxy groups at the 3beta, 12beta and 20 pro-S positions, in which the hydroxy groups at positions 3 and 20 have been converted to the corresponding beta-D-glucopyranosyl-(1->2)-beta-D-glucopyranoside and beta-D-xylopyranosyl-(1->6)-beta-D-glucopyranoside respectively, and in which a double bond has been introduced at the 24-25 position.


ginsenoside C-K

A ginsenoside found in Panax species that is dammarane which is substituted by hydroxy groups at the 3beta, 12beta and 20 pro-S positions, in which the hydroxy group at position 20 has been converted to the corresponding beta-D-glucopyranoside, and in which a double bond has been introduced at the 24-25 position.


A cholestanoid that is 5alpha-cholesta-8,14-dien-3beta-ol bearing two additional methyl substituents at position 4.


geranylgeranyl diphosphate

A polyprenol diphosphate having geranylgeranyl as the polyprenyl component.


carotene

Hydrocarbon carotenoids.


tetraterpenoid

Any terpenoid derived from a tetraterpene. The term includes compounds in which the C40 skeleton of the parent tetraterpene has been rearranged or modified by the removal of one or more skeletal atoms (generally methyl groups).


CITRONELLOL

A monoterpenoid that is oct-6-ene substituted by a hydroxy group at position 1 and methyl groups at positions 3 and 7.


A diastereomer of protopanaxadiol in which the 20-hydroxy substituent has been introduced at the pro-R position.


limonene

A monoterpene that is cyclohex-1-ene substituted by a methyl group at position 1 and a prop-1-en-2-yl group at position 4 respectively.


all-trans-retinyl octanoate

An all-trans-retinyl ester obtained by formal condensation of the carboxy group of octanoic acid with the hydroxy group of all-trans-retinol.


A tetracyclic triterpenoid that is dammarenediol-II where the hydrogen of the hydroxy group at position 20 is replaced by a beta-D-glucoside.


A pentacyclic triterpenod that is 9beta,19-cyclolanost-24-ene which is substituted by hydroxy groups at the 3beta and 28 positions.


squalene triterpenoid

A triterpenoid based on a  squalene skeleton and its substituted derivatives thereof.


GINSENOSIDE RF

A ginsenoside found in Panax ginseng and Panax japonicus var. major that is dammarane which is substituted by hydroxy groups at the 3beta, 6alpha, 12beta and 20 pro-S positions, in which the hydroxy group at position 6 has been converted to the corresponding beta-D-glucopyranosyl-(1->2)-beta-D-glucopyranoside, and in which a double bond has been introduced at the 24-25 position.


polyprenol phosphate

A prenol phosphate resulting from the formal condensation of the terminal allylic hydroxy group of a polyprenol with 1 mol eq. of phosphoric acid.


A car-3-ene (3,7,7-trimethylbicyclo[4.1.0]hept-3-ene) that has R configuration at position 1 and S configuration at position 6.


sesquiterpene

A C15 terpene.


polyprenol

Any member of the class of  prenols possessing the general formula H-[CH2C(Me)=CHCH2]nOH in which the carbon skeleton is composed of more than one isoprene units.


triterpenoid

Any terpenoid derived from a triterpene. The term includes compounds in which the C30 skeleton of the parent triterpene has been rearranged or modified by the removal of one or more skeletal atoms (generally methyl groups).


A steroid acid that is 4beta,14-dimethyl-5alpha,9beta-9,19-cyclocholest-24-en-3beta-ol in which the 4alpha hydrogen has been replaced by a carboxy group.


pneumocysterol

A tetracyclic triterpenoid that is (24Z)-24-ethylidenelanost-8-ene substituted by a hydroxy group at the 3beta position.


tetracyclic diterpenoid

A diterpenoid with a tetracyclic skeleton.


polyterpene

A C5n terpene, where n is greater than 8.


GINSENOSIDE RH2

A ginsenoside found in Panax species that is dammarane which is substituted by hydroxy groups at the 3beta, 12beta and 20 pro-S positions, in which the hydroxy group at position 3 has been converted to the corresponding beta-D-glucopyranoside, and in which a double bond has been introduced at the 24-25 position.


A cholestanoid that is 5alpha-cholesta-8-en-3beta-ol bearing two additional methyl substituents at position 4.


all-trans-3,4-didehydroretinoic acid

A retinoid obtained by 3,4-desaturation of beta-ionone ring of all-trans-retinoic acid


A car-3-ene (3,7,7-trimethylbicyclo[4.1.0]hept-3-ene) that has S configuration at position 1 and R configuration at position 6.


GINSENOSIDE RG2

A ginsenoside found in Panax species that is dammarane which is substituted by hydroxy groups at the 3beta, 6alpha, 12beta and 20 pro-S positions, in which the hydroxy group at position 6 has been converted to the corresponding alpha-L-rhamnopyranosyl-(1->2)-beta-D-glucopyranoside, and in which a double bond has been introduced at the 24-25 position.


terpene

A hydrocarbon of biological origin having carbon skeleton formally derived from isoprene [CH2=C(CH3)CH=CH2].


GINSENOSIDE RH1

A tetracyclic triterpenoid that is (20S)-protopanaxadiol which is substituted by beta-D-glucoside at the 6alpha position.


sesquiterpenoid

Any terpenoid derived from a sesquiterpene. The term includes compounds in which the C15 skeleton of the parent sesquiterpene has been rearranged or modified by the removal of one or more skeletal atoms (generally methyl groups).


GINSENOSIDE RC

A ginsenoside found in Panax ginseng that is dammarane which is substituted by hydroxy groups at the 3beta, 12beta and 20 pro-S positions, in which the hydroxy groups at positions 3 and 20 have been converted to the corresponding beta-D-glucopyranosyl-(1->2)-beta-D-glucopyranoside and alpha-L-arabinofuranosyl-(1->6)-beta-D-glucopyranoside respectively, and in which a double bond has been introduced at the 24-25 position.


(R)-(+)-perillyl alcohol

A perillyl alcohol in which the chiral centre has R configuration.


PERILLYL ALCOHOL

A perillyl alcohol in which the chiral centre has S configuration.


(+)-menthol

A p-menthan-3-ol which has (1S,2R,5S)-stereochemistry. In contrast to (-)-menthol, the (+)-enantiomer occurs only rarely in nature.


p-menthadiene

A monoterpene that consists of an unsaturated p-menthane skeleton having two double bonds.


A 3beta-hydroxy-4alpha-formyl-4beta-methylsteroid that is 9beta-9,19-cyclolanost-24-ene-3beta,28-diol in which the hydroxy group at position 28 has been oxidised to the corresponding aldehyde.


tetracyclic triterpenoid

Any triterpenoid consisting of a tetracyclic skeleton.


(+)-alpha-phellandrene

The (5S)-stereoisomer of alpha-phellandrene (5-isopropyl-2-methylcyclohexa-1,3-diene).


A squalene triterpenoid obtained by formal epoxidation across the 2,3 C=C bond of squalene.


all-trans-polyprenyl diphosphate

A polyprenol diphosphate of unspecified chain-length with all double bonds having (E)-configuration.


all-trans-retinyl dodecanoate

An all-trans-retinyl ester obtained by formal condensation of the carboxy group of dodecanoic (lauric) acid with the hydroxy group of all-trans-retinol.


ginsenoside Mc

A ginsenoside found in Panax notoginseng that is dammarane which is substituted by hydroxy groups at the 3beta, 12beta and 20 pro-S positions and in which the hydroxy group at position 20 has been converted to the corresponding alpha-L-arabinofuranosyl-beta-D-glucopyranoside.


A tetracyclic triterpenoid that is lanost-8-ene carrying hydroxy and oxo substituents at positions 3beta and 30 respectively.


acitretin

A retinoid that consists of 3,7-dimethylnona-2,4,6,8-tetraenoic acid having a 4-methoxy-2,3,6-trimethylphenyl group attached at position 9.


DISOGENIN

A  sapogenin that is spirostan which is substituted by a hydroxy group at the 3beta position, contains a double bond at the 5-6 position, and has R- configuration at position 25. A natural product found in Dioscorea (wild yam) species, it is used as the starting point for the commercial synthesis of a number of steroids, including cortisone, pregnenolone and progesterone.


eburicol

A tetracyclic triterpenoid that is 24,25-dihydrolanosterol carrying an additional methylene substituent at position 24. A natural product found in Taiwanofungus camphoratus.


protopanaxatriol

A tetracyclic triterpenoid sapogenin (isolated from ginseng and notoginseng) that is that is dammarane which is substituted by hydroxy groups at the 3beta, 6alpha, 12beta and 20 pro-S positions and in which a double bond has been introduced at the 24-25 position.


A 3beta-hydroxy-4alpha-formyl-4beta-methylsteroid that is 24-methylenecycloartanol in which the alpha-methyl substituent at position 4 has been substituted by a hydroxy group.


GINSENOSIDE RB2

A ginsenoside found in Panax ginseng that is dammarane which is substituted by hydroxy groups at the 3beta, 12beta and 20 pro-S positions, in which the hydroxy groups at positions 3 and 20 have been converted to the corresponding beta-D-glucopyranosyl-(1->2)-beta-D-glucopyranoside and alpha-L-arabinopyranosyl-(1->6)-beta-D-glucopyranoside respectively, and in which a double bond has been introduced at the 24-25 position.


A tetracyclic triterpenoid that is lanost-8-ene carrying two hydroxy substituents at positions 3beta and 30.


A diastereomer of protopanaxadiol in which the 20-hydroxy substituent has been introduced at the pro-S position.


monoterpenoid

Any terpenoid derived from a monoterpene. The term includes compounds in which the C10 skeleton of the parent monoterpene has been rearranged or modified by the removal of one or more skeletal atoms (generally methyl groups).


phorbol ester

Esters of phorbol, originally found in croton oil (from Croton tiglium, of the family Euphorbiaceae). A number of phorbol esters possess activity as tumour promoters and activate the mechanisms associated with cell growth. Some of these are used in experiments as activators of protein kinase C.


hainanic acid A

A tetracyclic triterpenoid isolated from the fruiting bodies of Ganoderma hainanense.


prenols

Any alcohol possessing the general formula H-[CH2C(Me)=CHCH2]nOH in which the carbon skeleton is composed of one or more isoprene units (biogenetic precursors of the isoprenoids).


xanthophyll

A subclass of carotenoids consisting of the oxygenated carotenes.


monoterpene

A C10 terpene.


ginsenoside C-Y

A ginsenoside found in Panax species that is dammarane which is substituted by hydroxy groups at the 3beta, 12beta and 20 pro-S positions, in which the hydroxy group at position 20 has been converted to the corresponding alpha-L-arabinopyranosyl-(1->6)-beta-D-glucopyranoside, and in which a double bond has been introduced at the 24-25 position.


A pentacyclic triterpenoid that is (9beta)-24-methylene-9,19-cyclolanostane which carries a hydroxy group at position 3beta. It is isolated from several plant species including Euphorbia, Epidendrum, Psychotria and Sideritis.


VITAMIN A2

A retinoid derived from 3,4-desaturation of the beta-ionone ring of all-trans-retinol.


alpha-carotene

A cyclic carotene with a beta- and an epsilon-ring at opposite ends respectively.


sclerodol B

A 3beta-hydroxy steroid that is (3beta,5alpha)-4,4,14-trimethylandrost-8-en-3-ol which is substituted by a (3E,6S)-2-methoxy-2-methylhept-3-en-6-yl group at position 17.


GANODEROL B

A tetracyclic triterpenoid that is lanosta-7,9(11),24-triene which is substituted by hydroxy groups at positions 3 and 27. It has been isolated from several Ganoderma species.


gypenoside LXXV

A ginsenoside found in Panax species that is dammarane which is substituted by hydroxy groups at the 3beta,  12beta and 20 pro-S positions, in which the hydroxy group at position 20 has been converted to the corresponding beta-D-glucopyranosyl-(1->6)-beta-D-glucopyranoside, and in which a double bond has been introduced at the 24-25 position.


trans,poly-cis-decaprenyl diphosphate

A decaprenyl diphosphate having (Z)-stereochemistry in all but one of the double bonds.


GINSENOSIDE F2

A ginsenoside found in Panax species that is dammarane which is substituted by hydroxy groups at the 3beta, 12beta and 20 pro-S positions, in which the hydroxy groups at positions 3 and 20 have been converted to the corresponding beta-D-glucopyranosides, and in which a double bond has been introduced at the 24-25 position.


A 3beta-hydroxy steroid having an ent-dammarane skeleton with a double bond at C-24 and a Z-double bond at C-17(20).


(S)-all-trans-4-hydroxyretinoic acid

An all-trans-4-hydroxyretinoic acid in which the 4-hydroxy group has S-configuration.


protopanaxadiol

A tetracyclic triterpenoid sapogenin (isolated from ginseng) that is dammarane which is substituted by hydroxy groups at the 3beta, 12beta and 20 positions and in which a double bond has been introduced at the 24-25 position.


retinol

A retinoid consisting of 3,7-dimethylnona-2,4,6,8-tetraen-1-ol substituted at position 9 by a 2,6,6-trimethylcyclohex-1-en-1-yl group (geometry of the four exocyclic double bonds is not specified).


retinoid

Oxygenated derivatives of 3,7-dimethyl-1-(2,6,6-trimethylcyclohex-1-enyl)nona-1,3,5,7-tetraene and derivatives thereof.


tetraterpene

A C40 terpene.


all-trans-retinyl tetradecanoate

An all-trans-retinyl ester obtained by formal condensation of the carboxy group of tetradecanoic acid with the hydroxy group of all-trans-retinol.


MOGROL

A tetracyclic triterpenoid that is cucurbitadienol in which the side-chain double bond (position 24-25) has undergone formal oxidation to introduce hydroxy groups at positions 24 and 25 (the 24R stereoisomer). It is a biometabolite of mogrosides found in Siraitia grosvenorii.


carotenoid beta-end derivative

Any carotenoid derivative with an beta-end group


beta-caryophyllene

A sesquiterpene with a [7.2.0]-bicyclic structure comprising fused 9- and 4-membered rings, with a trans-ring junction, a trans-double bond between the 4- and 5-positions of the 9-membered ring, a methylidene group at position 9, and methyl groups at positions 3, 11, and 11. The most commonly occurring form is the (1R,9S)-(-)-enantiomer, which is found in many essential oils, particularly clove oil.


terpenoid

Any isoprenoid that is a natural product or related compound formally derived from isoprene units. Terpenoids may contain oxygen in various functional groups. This class is subdivided according to the number of carbon atoms in the parent terpene. The skeleton of terpenoids may differ from strict additivity of isoprene units by the loss or shift of a fragment, generally a methyl group.


GINSENOSIDE RG1

A ginsenoside found in Panax ginseng and Panax japonicus var. major that is dammarane which is substituted by hydroxy groups at the 3beta, 6alpha, 12beta and 20 pro-S positions, in which the hydroxy groups at positions 6 and 20 have been converted to the corresponding beta-D-glucopyranosides, and in which a double bond has been introduced at the 24-25 position.


A 3beta-sterol that is lanosterol carrying an oxo group at position 26.


ginsenoside Mx

A ginsenoside found in Panax ginseng that is dammarane which is substituted by hydroxy groups at the 3beta, 12beta and 20 pro-S positions and in which the hydroxy group at position 20 has been converted to the corresponding beta-D-xylopyranosyl-beta-D-glucopyranoside.


carotenoid

One of a class of tetraterpenoids (C40), formally derived from the acyclic parent, psi,psi-carotene by hydrogenation, dehydrogenation, cyclization, oxidation, or combination of these processes. This class includes carotenes, xanthophylls and certain compounds that arise from rearrangement of the skeleton of psi,psi-carotene or by loss of part of this structure. Retinoids are excluded.


NOTOGINSENOSIDE R1

A ginsenoside found in Panax notoginseng that is dammarane which is substituted by hydroxy groups at the 3beta, 6alpha, 12beta and 20 pro-S positions, in which the hydroxy groups at positions 6 and 20 have been converted to the corresponding beta-D-xylopyranosyl-(1->2)-beta-D-glucopyranoside and beta-D-glucopyranoside respectively, and in which a double bond has been introduced at the 24-25 position.


parkeol

A tetracyclic triterpenoid comprised of a lanostane skeleton which is 3beta-hydroxylated and has double bonds at the 9(11)- and 24-positions.


all-trans-decaprenyl diphosphate

A decaprenyl diphosphate having (E)-stereochemistry exclusively in the double bonds.


GINSENOSIDE RE

A ginsenoside found in Panax ginseng that is dammarane which is substituted by hydroxy groups at the 3beta, 6alpha, 12beta and 20 pro-S positions, in which the hydroxy groups at positions 6 and 20 have been converted to the corresponding alpha-L-rhamnopyranosyl-(1->2)-beta-D-glucopyranoside and beta-D-glucopyranoside respectively, and in which a double bond has been introduced at the 24-25 position.


ALPHA-PINENE

A pinene that is bicyclo[3.1.1]hept-2-ene substituted by methyl groups at positions 2, 6 and 6 respectively.


GINSENOSIDE F1

A ginsenoside found in Panax species that is dammarane which is substituted by hydroxy groups at the 3beta, 6alpha, 12beta and 20 pro-S positions, in which the hydroxy group at position 20 has been converted to the corresponding beta-D-glucopyranoside, and in which a double bond has been introduced at the 24-25 position.


triterpene

A C30 terpene.


terpene glycoside

A terpenoid in which one or more hydroxy functions are glycosylated.


retinyl ester

A carboxylic ester obtained by formal condensation of the hydroxy group of retinol with the carboxy group of any carboxylic acid.


hexaprenyl diphosphate

A polyprenol diphosphate compound having six prenyl units with undefined stereochemistry about the double bonds.


GYPENOSIDE XVII

A ginsenoside found in Panax species that is dammarane which is substituted by hydroxy groups at the 3beta, 12beta and 20 pro-S positions, in which the hydroxy groups at positions 3 and 20 have been converted to the corresponding beta-D-glucopyranoside and beta-D-glucopyranosyl-(1->6)-beta-D-glucopyranoside respectively, and in which a double bond has been introduced at the 24-25 position.


apo carotenoid

A compound arising from loss of part of the carotene skeleton (excluding retinoids)


retinoic acid

A retinoid consisting of 3,7-dimethylnona-2,4,6,8-tetraenoic acid substituted at position 9 by a 2,6,6-trimethylcyclohex-1-en-1-yl group (geometry of the four exocyclic double bonds is not specified).


A decaprenyl diphosphate having (Z)-stereochemistry about all but one of the double bonds.


CYCLOLAUDENOL (24S)

A pentacyclic triterpenoid that is (24S)-methyl-9beta,19-cyclolanost-25-ene which carries a hydroxy group at position 3beta. It is isolated from several plant species inclduing Turraeanthus  and Tillandsia.


all-trans-retinyl heptanoate

An all-trans-retinyl ester obtained by formal condensation of the carboxy group of heptanoic acid with the hydroxy group of all-trans-retinol.


carveol

A limonene monoterpenoid that is cyclohex-2-en-1-ol substituted by a methyl group at position 2 and a prop-1-en-2-yl group at position 5.


all-trans-retinyl ester

A retintinyl ester in which all double bonds of the retinyl side-chain have trans-configuration.


diterpenoid

Any terpenoid derived from a diterpene. The term includes compounds in which the C20 skeleton of the parent diterpene has been rearranged or modified by the removal of one or more skeletal atoms (generally methyl groups).


undecaprenyl diphosphate

A polyprenol diphosphate compound having eleven prenyl units with undefined stereochemistry about the double bonds.


A 3beta-sterol that is lanosterol carrying a hydroxy group at position 26.


triterpenoid saponin

A terpene glycoside in which the terpene moiety is a triterpenoid.


ALPHA-PHELLANDRENE

The (R)-(-)-stereoisomer of alpha-phellandrene.


name: sperm-egg fusion protein Juno isoform h2 (human)

description: A sperm-egg fusion protein Juno (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:A6ND01-2.


name: sperm-egg fusion protein Juno isoform h1 (human)

description: A sperm-egg fusion protein Juno (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:A6ND01-1.


name: phenylalanine--tRNA ligase alpha subunit isoform h2 (human)

description: A phenylalanine--tRNA ligase alpha subunit (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9Y285-2.


name: tRNA modification GTPase GTPBP3, mitochondrial isoform h3 (human)

description: A tRNA modification GTPase GTPBP3, mitochondrial (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q969Y2-3.


A heme that consists of sirohaem lacking the two carboxy groups at positions 12 and 18.


ferroheme

Any iron(II)--porphyrin coordination complex.


name: cis-heme d hydroxychlorin gamma-spirolactone methyl ester

description: A carboxylic ester that is the methyl ester of cis-heme d hydroxychlorin gamma-spirolactone.


ferroheme o

A ferroheme having a methyl group at ring position 8 and an isoprenoid chain at position 2.


heme b

A metalloprotoporphyrin in which the four pyrrole nitrogens of the protoporphyrin moiety are coordinated to iron. It is the most abundant of the heme compounds.


ferroheme b

Heme b in which the iron has oxidation state +2.


ferriheme b

Heme b in which the iron has oxidation state +3.


heme d trans-diol

A metallochlorin that is ferroheme b which is trans-dihydroxylated at positions 5 and 6.


name: cis-heme d hydroxychlorin gamma-spirolactone

description: A metallochlorin that is heme d in which the hydroxy group and the carboxy group of the 6-carboxyethyl substituent have undergone intramolecular condensation to afford the corresponding gamma-spirolactone.


ferriheme a(1-)

Ferriheme a protonated to pH 7.3.


ferroheme c

A ferroheme coordination complex bearing 1-sulfanylethyl substituents at the 8- and 13-positions.


iron methylchlorin

A metallochlorin that is the iron(II) complex of 7,8-dihydroporphyrin which is substituted by methyl groups at positions 3, 7, 7, 8, 12, 13, and 17, and by carboxyethyl groups at positions 2 and 18.


heme d cis-diol

A metallochlorin that is ferroheme b which is cis-dihydroxylated at positions 5 and 6.


name: trans-heme d hydroxychlorin gamma-spirolactone

description: A metallochlorin that is ferroheme b which is hydroxylated at positions 5 and 6, and in which the resulting 6-hydroxy group undergoes formal condensation with the carboxy group of the 6-carboxyethyl group to afford the corresponding spirolactone in which the oxygen atoms at positions 5 and 6 are trans to each other.


ferriheme b(1-)

Ferriheme b carrying an overall charge of -1, caused by loss of a proton from each of the two carboxy groups.


ferriheme

Any iron(III)--porphyrin coordination complex.


ferriheme a

A ferriheme in which the 1-hydroxy group has S-configuration.


ferriheme a3

A ferriheme consisting of a tetraporphyrin derivative coordinated to a central iron.


ferroheme d1

A ferroheme having four carboxy groups and oxo groups on two of the pyrrole rings.


name: endothelin-converting enzyme 1 deaminated 3 (human)

description: An endothelin-converting enzyme 1 (human) that has been deaminated on the residue at the position equivalent to Asn-660 of the amino acid sequence represented by UniProtKB:P42892-1. Example: UniProtKB:P42892-1, Asn-660, MOD:00684.


name: cadherin-related family member 1 isoform h2 (human)

description: A cadherin-related family member 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q96JP9-2.


name: cadherin-related family member 1 isoform h1 (human)

description: A cadherin-related family member 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q96JP9-1.


name: dual specificity protein kinase CLK4 phosphorylated 1 (human)

description: A dual specificity protein kinase CLK4 (human) that has been phosphorylated on the residue at the position equivalent to Tyr-303 of the amino acid sequence represented by UniProtKB:Q9HAZ1. UniProtKB:Q9HAZ1, Tyr-303, MOD:00048.


5-fluoroanthranilic acid

An aminobenzoic acid that is anthranilic acid in which the hydrogen at position 5 on the phenyl ring is replaced by fluorine.


name: leukotriene A-4 hydrolase hydroxylated 1 (human)

description: A leukotriene A-4 hydrolase (human) that has been hydroxylated on the residue at the position equivalent to Trp-425 of the amino acid sequence represented by UniProtKB:P09960-1. Example: UniProtKB:P09960-1, Trp-425, MOD:01622.


name: leukotriene A-4 hydrolase isoform h2 (human)

description: A leukotriene A-4 hydrolase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P09960-2.


name: leukotriene A-4 hydrolase isoform 1 (human)

description: A leukotriene A-4 hydrolase isoform 1 that is encoded in the genome of human.


name: leukotriene A-4 hydrolase isoform h3 (human)

description: A leukotriene A-4 hydrolase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P09960-3.


name: leukotriene A-4 hydrolase, initiator methionine removed form (human)

description: A leukotriene A-4 hydrolase (human) that has had the initiator methionine removed. UniProtKB:P09960, 2-611.


name: leukotriene A-4 hydrolase deaminated 1 (human)

description: A leukotriene A-4 hydrolase (human) that has been deaminated on the residue at the position equivalent to Asn-467 of the amino acid sequence represented by UniProtKB:P09960-1. Example: UniProtKB:P09960-1, Asn-467, MOD:00684.


name: leukotriene A-4 hydrolase isoform h4 (human)

description: A leukotriene A-4 hydrolase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P09960-4.


name: hypoxia-inducible factor 1-alpha inhibitor cysteinylated 1 (human)

description: A hypoxia-inducible factor 1-alpha inhibitor (human) that has been cysteinylated on the residue at the position equivalent to Cys-226 of the amino acid sequence represented by UniProtKB:Q9NWT6. UniProtKB:Q9NWT6, Cys-226, MOD:00765.


name: receptor tyrosine-protein kinase erbB-2 sequence variant R896H, signal peptide removed form (human)

description: A receptor tyrosine-protein kinase erbB-2 (human) that has a His residue at the position equivalent to Arg-896 of the amino acid sequence represented by UniProtKB:P04626-1 and that has had the signal peptide removed. Example: UniProtKB:P04626-1, 23-1255, Arg-896, CHEBI:29979.


name: aggrecan core protein O-glycosylated 88 (human)

description: An aggrecan core protein (human) that has been O-glycosylated at the residue equivalent to Thr-2258 of the amino acid sequence represented by UniProtKB:P16112-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P16112-1, Thr-2258, MOD:00005~GNO:G43417UB.


phospholemman isoform 1 (human)

A phospholemman isoform 1 that is encoded in the genome of human.


phospholemman

A protein that is a translation product of the human FXYD1 gene or a 1:1 ortholog thereof.


name: phospholemman, signal peptide removed form (human)

description: A phospholemman (human) that has had the signal peptide removed. UniProtKB:O00168, 21-92.


name: histone H2A type 1-G/I/K/L/M, initiator methionine removed omega-methylated 2 (human)

description: A histone H2A type 1-G/I/K/L/M (human) that has had the initiator methionine removed and that has been omega-methylated on the residue at the position equivalent to Arg-12 of the amino acid sequence represented by UniProtKB:P0C0S8. UniProtKB:P0C0S8, 2-130, Arg-12, MOD:00078.


name: WD repeat domain phosphoinositide-interacting protein 1 isoform 1 (human)

description: A WD repeat domain phosphoinositide-interacting protein 1 isoform 1 that is encoded in the genome of human.


name: CDC42 small effector protein 1 phosphorylated 2 (human)

description: A CDC42 small effector protein 1 (human) that has been phosphorylated on the residue at the position equivalent to Ser-74 of the amino acid sequence represented by UniProtKB:Q9NRR8-1. Example: UniProtKB:Q9NRR8-1, Ser-74, MOD:00046.


name: transcription factor Sp1 isoform 1 cleaved 1 (human)

description: A transcription factor Sp1 isoform 1 cleaved 1 in human. UniProtKB:P08047-1, 65-785.


Y+L amino acid transporter 1

A protein that is a translation product of the human SLC7A7 gene or a 1:1 ortholog thereof.


name: Y+L amino acid transporter 1 sequence variant L334R (human)

description: A Y+L amino acid transporter 1 (human) that has an Arg residue at the position equivalent to Leu-334 of the amino acid sequence represented by UniProtKB:Q9UM01. UniProtKB:Q9UM01, Leu-334, CHEBI:29952.


name: Y+L amino acid transporter 1 sequence variant T188I (human)

description: A Y+L amino acid transporter 1 (human) that has an Ile residue at the position equivalent to Thr-188 of the amino acid sequence represented by UniProtKB:Q9UM01. UniProtKB:Q9UM01, Thr-188, CHEBI:30009.


name: Y+L amino acid transporter 1 cysteinylated 1 (human)

description: A Y+L amino acid transporter 1 (human) that has been cysteinylated on the residue at the position equivalent to Cys-151 of the amino acid sequence represented by UniProtKB:Q9UM01. UniProtKB:Q9UM01, Cys-151, MOD:00765.


name: Y+L amino acid transporter 1 sequence variant M50K (human)

description: A Y+L amino acid transporter 1 (human) that has a Lys residue at the position equivalent to Met-50 of the amino acid sequence represented by UniProtKB:Q9UM01. UniProtKB:Q9UM01, Met-50, CHEBI:29967.


name: aflatoxin B1 aldehyde reductase member 4 isoform h1 (human)

description: An aflatoxin B1 aldehyde reductase member 4 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8NHP1-1.


name: protein mono-ADP-ribosyltransferase PARP14 deaminated 2 (human)

description: A protein mono-ADP-ribosyltransferase PARP14 (human) that has been deaminated on the residue at the position equivalent to Gln-733 of the amino acid sequence represented by UniProtKB:Q460N5-6. Example: UniProtKB:Q460N5-6, Gln-733, MOD:00685.


name: Ras and Rab interactor 3 deaminated 1 (human)

description: A Ras and Rab interactor 3 (human) that has been deaminated on the residue at the position equivalent to Gln-716 of the amino acid sequence represented by UniProtKB:Q8TB24-1. Example: UniProtKB:Q8TB24-1, Gln-716, MOD:00685.


name: 14-3-3 protein beta/alpha cysteinylated 1 (human)

description: A 14-3-3 protein beta/alpha (human) that has been cysteinylated on the residue at the position equivalent to Cys-191 of the amino acid sequence represented by UniProtKB:P31946-1. Example: UniProtKB:P31946-1, Cys-191, MOD:00765.


name: 14-3-3 protein beta/alpha isoform Long (human)

description: A 14-3-3 protein beta/alpha isoform 1 that is encoded in the genome of human.


name: 14-3-3 protein beta/alpha methylated 1 (human)

description: A 14-3-3 protein beta/alpha (human) that has been methylated on the residue at the position equivalent to Cys-191 of the amino acid sequence represented by UniProtKB:P31946-1. Example: UniProtKB:P31946-1, Cys-191, MOD:00660.


name: 14-3-3 protein beta/alpha isoform Short (human)

description: A 14-3-3 protein beta/alpha isoform 2 that is encoded in the genome of human.


name: DNA damage-binding protein 1 methylated 3 (human)

description: A DNA damage-binding protein 1 (human) that has been methylated on the residue at the position equivalent to Cys-87 of the amino acid sequence represented by UniProtKB:Q16531-1. Example: UniProtKB:Q16531-1, Cys-87, MOD:00660.


name: pulmonary surfactant-associated protein A1

description: A protein that is a translation product of the human SFTPA1 gene or a 1:1 ortholog thereof.


name: pulmonary surfactant-associated protein A1 isoform h2 (human)

description: A pulmonary surfactant-associated protein A1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8IWL2-2.


name: pulmonary surfactant-associated protein A1 isoform h1 (human)

description: A pulmonary surfactant-associated protein A1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8IWL2-1.


name: pulmonary surfactant-associated protein A1, signal peptide removed form (human)

description: A pulmonary surfactant-associated protein A1 (human) that has had the signal peptide removed. UniProtKB:Q8IWL2, 21-248.


periodontal disorder

description: An inflammatory process of the gingival tissues and/or periodontal membrane of the teeth, resulting in an abnormally deep gingival sulcus, possibly producing periodontal pockets and loss of alveolar bone support.


chronic periodontitis

description: A chronic inflammatory process that affects the tissues that surround and support the teeth.


name: brevican core protein O-glycosylated 1 (human)

description: A brevican core protein (human) that has been O-glycosylated at the residue equivalent to Thr-384 of the amino acid sequence represented by UniProtKB:Q96GW7-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:Q96GW7-1, Thr-384, MOD:00005~GNO:G43417UB.


name: E3 ubiquitin-protein ligase RNF128 isoform 1 (human)

description: An E3 ubiquitin-protein ligase RNF128 isoform 1 that is encoded in the genome of human.


name: Vam6/Vps39-like protein isoform 1 (human)

description: A Vam6/Vps39-like protein isoform 1 that is encoded in the genome of human.


name: tissue-type plasminogen activator N-glycosylated 79 (human)

description: A tissue-type plasminogen activator (human) that has been N-glycosylated at the residue equivalent to Asn-483 of the amino acid sequence represented by UniProtKB:P00750-1, in which the glycan structure is represented by GlyTouCan:G02000AU. Example: UniProtKB:P00750-1, Asn-483, MOD:00160~GNO:G02000AU.


name: DNA-directed RNA polymerase I subunit RPA49 cysteinylated 1 (human)

description: A DNA-directed RNA polymerase I subunit RPA49 (human) that has been cysteinylated on the residue at the position equivalent to Cys-85 of the amino acid sequence represented by UniProtKB:Q9GZS1-2. Example: UniProtKB:Q9GZS1-2, Cys-85, MOD:00765.


name: DNA-directed RNA polymerase I subunit RPA49 deaminated 1 (human)

description: A DNA-directed RNA polymerase I subunit RPA49 (human) that has been deaminated on the residue at the position equivalent to Gln-358 of the amino acid sequence represented by UniProtKB:Q9GZS1-2. Example: UniProtKB:Q9GZS1-2, Gln-358, MOD:00685.


name: DNA-directed RNA polymerase I subunit RPA49 isoform h2 (human)

description: A DNA-directed RNA polymerase I subunit RPA49 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9GZS1-2.


name: DNA-directed RNA polymerase I subunit RPA49 isoform h1 (human)

description: A DNA-directed RNA polymerase I subunit RPA49 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9GZS1-1.


name: DNA-directed RNA polymerase I subunit RPA49 methylated 1 (human)

description: A DNA-directed RNA polymerase I subunit RPA49 (human) that has been methylated on the residue at the position equivalent to Cys-253 of the amino acid sequence represented by UniProtKB:Q9GZS1-2. Example: UniProtKB:Q9GZS1-2, Cys-253, MOD:00660.


name: tyrosine-protein phosphatase non-receptor type 11 phosphorylated 1 (human)

description: A tyrosine-protein phosphatase non-receptor type 11 (human) that has been phosphorylated on the residue at the position equivalent to Tyr-546 of the amino acid sequence represented by UniProtKB:Q06124. UniProtKB:Q06124, Tyr-546, MOD:00048.


name: CUB and zona pellucida-like domain-containing protein 1 isoform h3 (human)

description: A CUB and zona pellucida-like domain-containing protein 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q86UP6-3.


name: CUB and zona pellucida-like domain-containing protein 1 isoform h1 (human)

description: A CUB and zona pellucida-like domain-containing protein 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q86UP6-1.


name: CUB and zona pellucida-like domain-containing protein 1 isoform h2 (human)

description: A CUB and zona pellucida-like domain-containing protein 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q86UP6-2.


name: triggering receptor expressed on myeloid cells 2 sequence variant A196T (human)

description: A triggering receptor expressed on myeloid cells 2 sequence variant (human) that has a Thr residue at the position equivalent to Ala-196 of the amino acid sequence represented by UniProtKB:Q9NZC2-1. Example: UniProtKB:Q9NZC2-1, Ala-196, CHEBI:30013.


name: cartilage oligomeric matrix protein sequence variant D290N (human)

description: A cartilage oligomeric matrix protein (human) that has an Asn residue at the position equivalent to Asp-290 of the amino acid sequence represented by UniProtKB:P49747-1. Example: UniProtKB:P49747-1, Asp-290, CHEBI:50347.


name: poly [ADP-ribose] polymerase 2 ADP-ribosylglutamate form (human)

description: A poly [ADP-ribose] polymerase 2 (human) that includes at least one ADP-ribosylated glutamic acid. UniProtKB:Q9UGN5, MOD:00300.


neuferricin cysteinylated 2 (human)

A neuferricin (human) that has been cysteinylated on the residue at the position equivalent to Cys-217 of the amino acid sequence represented by UniProtKB:Q8WUJ1-1. Example: UniProtKB:Q8WUJ1-1, Cys-217, MOD:00765.


name: long-chain-fatty-acid--CoA ligase 6 isoform h7 (human)

description: A long-chain-fatty-acid--CoA ligase 6 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9UKU0-7.


name: protein kinase C epsilon type isoform 1 (human)

description: A protein kinase C epsilon isoform 1 that is encoded in the genome of human.


name: 14-3-3 protein gamma methylated 2 (human)

description: A 14-3-3 protein gamma (human) that has been methylated on the residue at the position equivalent to Cys-194 of the amino acid sequence represented by UniProtKB:P61981. UniProtKB:P61981, Cys-194, MOD:00660.


polyazaalkane

Any azaalkane in which two or more carbons in the chain are replaced by nitrogen.


A spermidine in which four carbon atoms have been replaced by the (13)C isotope.


alkane-alpha,omega-diamine

A primary diamine that is ethane or a higher alkane in which a hydrogen of each of the terminal methyl groups has been replaced by an amino group. H2NCH2(CH2)nCH2NH2, where n = 0, 1, 2, etc.


tyrosine-protein kinase Fer

A protein that is a translation product of the human FER gene or a 1:1 ortholog thereof.


name: tyrosine-protein kinase Fer isoform 1 (human)

description: A tyrosine-protein kinase Fer (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P16591-1.


name: tyrosine-protein kinase Fer isoform 3 (human)

description: A tyrosine-protein kinase Fer isoform 3 that is encoded in the genome of human.


name: tyrosine-protein kinase Fer isoform h2 (human)

description: A tyrosine-protein kinase Fer (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P16591-2.


name: diamine acetyltransferase 1 isoform 1 (human)

description: A diamine acetyltransferase 1 isoform 1 that is encoded in the genome of human.


name: diamine acetyltransferase 1 methylated 1 (human)

description: A diamine acetyltransferase 1 (human) that has been methylated on the residue at the position equivalent to Cys-54 of the amino acid sequence represented by UniProtKB:P21673. UniProtKB:P21673, Cys-54, MOD:00660.


name: DNA-directed RNA polymerases I, II, and III subunit RPABC3 isoform 1 (human)

description: A DNA-directed RNA polymerases I, II, and III subunit RPABC3 isoform 1 that is encoded in the genome of human.


name: aminoglycoside phosphotransferase domain-containing protein 1

description: A protein that is a translation product of the human HYKK gene or a 1:1 ortholog thereof.


hydroxylysine kinase isoform h2 (human)

A hydroxylysine kinase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:A2RU49-2.


hydroxylysine kinase isoform h1 (human)

A hydroxylysine kinase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:A2RU49-1.


hydroxylysine kinase isoform h3 (human)

A hydroxylysine kinase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:A2RU49-3.


name: eIF-2-alpha kinase GCN2 isoform h2 (human)

description: An eIF-2-alpha kinase GCN2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9P2K8-2.


name: versican core protein O-glycosylated 128 (human)

description: A versican core protein (human) that has been O-glycosylated at the residue equivalent to Thr-1734 of the amino acid sequence represented by UniProtKB:P13611-1, in which the glycan composition is represented by GlyTouCan:G88713AC. Example: UniProtKB:P13611-1, Thr-1734, MOD:00005~GNO:G88713AC.


serine/threonine-protein kinase PRKX

A protein that is a translation product of the human PRKX gene or a 1:1 ortholog thereof.


name: cAMP-dependent protein kinase catalytic subunit PRKX deaminated 1 (human)

description: A cAMP-dependent protein kinase catalytic subunit PRKX (human) that has been deaminated on the residue at the position equivalent to Asn-177 of the amino acid sequence represented by UniProtKB:P51817. UniProtKB:P51817, Asn-177, MOD:00684.


name: eukaryotic peptide chain release factor subunit 1, initiator methionine removed monomethylated 1 (human)

description: A eukaryotic peptide chain release factor subunit 1 (human) that has had the initiator methionine removed and that has been monomethylated on the residue at the position equivalent to Gln-185 of the amino acid sequence represented by UniProtKB:P62495-1. Example: UniProtKB:P62495-1, 2-437, Gln-185, MOD:00080.


name: ribosomal protein S6 kinase beta-1 isoform 1 phosphorylated 1 (human)

description: A ribosomal protein S6 kinase beta-1 isoform 1 phosphorylated 1 in human. UniProtKB:P23443-1, Ser-441/Ser-447, MOD:00046|Thr-444, MOD:00047.


name: fibroblast growth factor receptor 2 isoform 1 sequence variant A315T, signal peptide removed form (human)

description: A fibroblast growth factor receptor 2 isoform 1 (human) that has a Thr residue at the position equivalent to Ala-315 of the amino acid sequence represented by UniProtKB:P21802-1 and that has had the signal peptide removed. UniProtKB:P21802-1, 22-821, Ala-315, CHEBI:30013.


importin-11 deaminated 1 (human)

An importin-11 (human) that has been deaminated on the residue at the position equivalent to Gln-935 of the amino acid sequence represented by UniProtKB:Q9UI26-1. Example: UniProtKB:Q9UI26-1, Gln-935, MOD:00685.


name: guanine nucleotide-binding protein G(t) subunit alpha-3 isoform 1 (human)

description: A guanine nucleotide-binding protein G(t) subunit alpha-3 isoform 1 that is encoded in the genome of human.


name: 14 kDa phosphohistidine phosphatase isoform h1 (human)

description: A 14 kDa phosphohistidine phosphatase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9NRX4-1.


name: transcriptional regulator ATRX sequence variant R808* (human)

description: A transcriptional regulator ATRX (human) that has has been truncated after the position equivalent to Lys-807 of the amino acid sequence represented by UniProtKB:P46100-1. Example: UniProtKB:P46100-1, 1-807.


name: glutamate--cysteine ligase catalytic subunit sequence variant R127C (human)

description: A glutamate--cysteine ligase catalytic subunit (human) that has a Cys residue at the position equivalent to Arg-127 of the amino acid sequence represented by UniProtKB:P48506. UniProtKB:P48506, Arg-127, CHEBI:29950.


name: guanylyl cyclase-activating protein 2, initiator methionine removed form (human)

description: A guanylyl cyclase-activating protein 2 (human) that has had the initiator methionine removed. UniProtKB:Q9UMX6, 2-200.


guanylyl cyclase-activating protein 2

A protein that is a translation product of the human GUCA1B gene or a 1:1 ortholog thereof.


name: trimethyllysine dioxygenase, mitochondrial isoform h5 (human)

description: A trimethyllysine dioxygenase, mitochondrial (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9NVH6-5.


ceruloplasmin N-glycosylated 62 (human)

A ceruloplasmin (human) that has been N-glycosylated at the residue equivalent to Asn-762 of the amino acid sequence represented by UniProtKB:P00450-1, in which the glycan composition is represented by GlyTouCan:G27947YN. Example: UniProtKB:P00450-1, Asn-762, MOD:00160~GNO:G27947YN.


name: cyclin-dependent kinase 9 phosphorylated 1 (human)

description: A cyclin-dependent kinase 9 (human) that has been phosphorylated on the residue at the position equivalent to Thr-186 of the amino acid sequence represented by UniProtKB:P50750-1. Example: UniProtKB:P50750-1, Thr-186, MOD:00047.


name: exostosin-1 sequence variant G339D (human)

description: An exostosin-1 (human) that has an Asp residue at the position equivalent to Gly-339 of the amino acid sequence represented by UniProtKB:Q16394. UniProtKB:Q16394, Gly-339, CHEBI:29958.


name: peptidyl-prolyl cis-trans isomerase H methylated 1 (human)

description: A peptidyl-prolyl cis-trans isomerase H (human) that has been methylated on the residue at the position equivalent to Cys-47 of the amino acid sequence represented by UniProtKB:O43447-1. Example: UniProtKB:O43447-1, Cys-47, MOD:00660.


name: programmed cell death protein 6 isoform 2 (human)

description: A programmed cell death protein 6 isoform 2 that is encoded in the genome of human.


name: alpha-ketoglutarate-dependent dioxygenase FTO isoform m1 (mouse)

description: An alpha-ketoglutarate-dependent dioxygenase FTO (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8BGW1-1.


name: alpha-ketoglutarate-dependent dioxygenase FTO isoform m3 (mouse)

description: An alpha-ketoglutarate-dependent dioxygenase FTO (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8BGW1-3.


name: alpha-ketoglutarate-dependent dioxygenase FTO isoform m2 (mouse)

description: An alpha-ketoglutarate-dependent dioxygenase FTO (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8BGW1-2.


name: alpha-ketoglutarate-dependent dioxygenase FTO isoform m4 (mouse)

description: An alpha-ketoglutarate-dependent dioxygenase FTO (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8BGW1-4.


name: TGF-beta receptor type-1 sequence variant R414*, signal peptide removed phosphorylated 1 (human)

description: A TGF-beta receptor type-1 (human) that has has been truncated after the position equivalent to Arg-413 of the amino acid sequence represented by UniProtKB:P36897-1, that has had the signal peptide removed, and that has been phosphorylated on the residues at the positions equivalent to Ser-165, Thr-185, Thr-186, Ser-187, Ser-189, and Ser-191. Example: UniProtKB:P36897-1, 34-413, Ser-165/Ser-187/Ser-189/Ser-191, MOD:00046|Thr-185/Thr-186, MOD:00047.


name: phosphatidylinositol transfer protein alpha isoform, initiator methionine removed form (human)

description: A phosphatidylinositol transfer protein alpha isoform (human) that has had the initiator methionine removed. UniProtKB:Q00169, 2-270.


name: tumor necrosis factor isoform 1 myristoylated 1 (human)

description: A tumor necrosis factor isoform 1 myristoylated 1 in human. UniProtKB:P01375-1, Lys-19/Lys-20, MOD:00087.


name: mothers against decapentaplegic homolog 3 sequence variant D258N phosphorylated 1 (human)

description: A mothers against decapentaplegic homolog 3 (human) that has an Asn residue at the position equivalent to Asp-258 of the amino acid sequence represented by UniProtKB:P84022-1 and that has been phosphorylated on the residues at the positions equivalent to Ser-423 and Ser-425. Example: UniProtKB:P84022-1, Asp-258, CHEBI:50347|Ser-423/Ser-425, MOD:00046.


name: dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A methylated 4 (human)

description: A dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A (human) that has been methylated on the residue at the position equivalent to Cys-198 of the amino acid sequence represented by UniProtKB:P46977-1. Example: UniProtKB:P46977-1, Cys-198, MOD:00660.


name: tropomyosin beta chain isoform 2 (human)

description: A tropomyosin beta chain isoform 2 that is encoded in the genome of human.


name: P-selectin glycoprotein ligand 1 isoform h2 (human)

description: A P-selectin glycoprotein ligand 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q14242-2.


name: spectrin alpha chain, non-erythrocytic 1 isoform 3 (human)

description: A spectrin alpha chain, non-erythrocytic 1 isoform 3 that is encoded in the genome of human.


name: prolow-density lipoprotein receptor-related protein 1 O-glycosylated 9 (human)

description: A prolow-density lipoprotein receptor-related protein 1 (human) that has been O-glycosylated at the residue equivalent to Thr-2857 of the amino acid sequence represented by UniProtKB:Q07954-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:Q07954-1, Thr-2857, MOD:00005~GNO:G43417UB.


name: vitamin K-dependent gamma-carboxylase deaminated 2 (human)

description: A vitamin K-dependent gamma-carboxylase (human) that has been deaminated on the residue at the position equivalent to Asn-525 of the amino acid sequence represented by UniProtKB:P38435-1. Example: UniProtKB:P38435-1, Asn-525, MOD:00684.


A 1-glycosyltriazole in which the glycosyl residue is specified as ribosyl.


name: ubiquitin-conjugating enzyme E2 K isoform h2 (human)

description: A ubiquitin-conjugating enzyme E2 K (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P61086-2.


name: ubiquitin-conjugating enzyme E2 K isoform 1 (human)

description: A ubiquitin-conjugating enzyme E2 K isoform 1 that is encoded in the genome of human.


name: ubiquitin-conjugating enzyme E2 K, initiator methionine removed form (human)

description: A ubiquitin-conjugating enzyme E2 K (human) that has had the initiator methionine removed. UniProtKB:P61086, 2-200.


name: ubiquitin-conjugating enzyme E2 K isoform h3 (human)

description: A ubiquitin-conjugating enzyme E2 K (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P61086-3.


name: glycerol-3-phosphate phosphatase methylated 1 (human)

description: A glycerol-3-phosphate phosphatase (human) that has been methylated on the residue at the position equivalent to Cys-217 of the amino acid sequence represented by UniProtKB:A6NDG6. UniProtKB:A6NDG6, Cys-217, MOD:00660.


name: collagen alpha-1(XVIII) chain O-glycosylated 43 (human)

description: A collagen alpha-1(XVIII) chain (human) that has been O-glycosylated at the residue equivalent to Thr-736 of the amino acid sequence represented by UniProtKB:P39060-3, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P39060-3, Thr-736, MOD:00005~GNO:G43417UB.


name: phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform sequence variant R38S (human)

description: A phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (human) that has a Ser residue at the position equivalent to Arg-38 of the amino acid sequence represented by UniProtKB:P42336. UniProtKB:P42336, Arg-38, CHEBI:29999.


beta adrenergic receptor

An adrenoceptor protein whose active form binds adrenaline and related compounds and whose activity is mediated by G proteins that cause activation of adenylate cyclase.


beta-3 adrenergic receptor

A beta adrenergic receptor that is a translation product of the human ADRB3 gene or a 1:1 ortholog thereof.


name: beta-2 adrenergic receptor phosphoserine form (human)

description: A beta-2 adrenergic receptor (human) that includes at least one phosphorylated serine. UniProtKB:P07550, MOD:00046.


beta-1 adrenergic receptor

A beta adrenergic receptor that is a translation product of the human ADRB1 gene or a 1:1 ortholog thereof.


name: beta-1 adrenergic receptor phosphorylated 1 (human)

description: A beta-1 adrenergic receptor (human) that has been phosphorylated at Ser-312. UniProtKB:P08588, Ser-312, MOD:00046.


name: beta-2 adrenergic receptor ubiquitinated form (human)

description: A beta-2 adrenergic receptor (human) that includes at least one ubiquitinated lysine. UniProtKB:P07550, MOD:01148.


beta-2 adrenergic receptor

A beta adrenergic receptor that is a translation product of the human ADRB2 gene or a 1:1 ortholog thereof.


name: beta-2 adrenergic receptor phosphorylated 1 (human)

description: A beta-2 adrenergic receptor (human) that has been phosphorylated at Tyr-141. UniProtKB:P07550, Tyr-141, MOD:00048.


name: GTP-binding protein Rit2 isoform 1 (human)

description: A GTP-binding protein Rit2 isoform 1 that is encoded in the genome of human.


name: protein-S-isoprenylcysteine O-methyltransferase deaminated 2 (human)

description: A protein-S-isoprenylcysteine O-methyltransferase (human) that has been deaminated on the residue at the position equivalent to Asn-127 of the amino acid sequence represented by UniProtKB:O60725. UniProtKB:O60725, Asn-127, MOD:00684.


A protein that is a translation product of the human ICMT gene or a 1:1 ortholog thereof.


name: protein-S-isoprenylcysteine O-methyltransferase deaminated 3 (human)

description: A protein-S-isoprenylcysteine O-methyltransferase (human) that has been deaminated on the residue at the position equivalent to Gln-224 of the amino acid sequence represented by UniProtKB:O60725. UniProtKB:O60725, Gln-224, MOD:00685.


name: protein-S-isoprenylcysteine O-methyltransferase deaminated 1 (human)

description: A protein-S-isoprenylcysteine O-methyltransferase (human) that has been deaminated on the residue at the position equivalent to Asn-52 of the amino acid sequence represented by UniProtKB:O60725. UniProtKB:O60725, Asn-52, MOD:00684.


name: phosphatidylinositol 3-kinase catalytic subunit type 3 deaminated 3 (human)

description: A phosphatidylinositol 3-kinase catalytic subunit type 3 (human) that has been deaminated on the residue at the position equivalent to Gln-620 of the amino acid sequence represented by UniProtKB:Q8NEB9. UniProtKB:Q8NEB9, Gln-620, MOD:00685.


name: vitamin K-dependent protein C N-glycosylated 3 (human)

description: A vitamin K-dependent protein C (human) that has been N-glycosylated at the residue equivalent to Asn-139 of the amino acid sequence represented by UniProtKB:P04070-1, in which the glycan structure is represented by GlyTouCan:G32246SI. Example: UniProtKB:P04070-1, Asn-139, MOD:00160~GNO:G32246SI.


name: protein-glucosylgalactosylhydroxylysine glucosidase isoform h2 (human)

description: A protein-glucosylgalactosylhydroxylysine glucosidase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q32M88-2.


A protein that is a translation product of the human PGGHG gene or a 1:1 ortholog thereof.


name: protein-glucosylgalactosylhydroxylysine glucosidase isoform 2 (chicken)

description: A protein-glucosylgalactosylhydroxylysine glucosidase (chicken) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:F1NZI4-2.


name: protein-glucosylgalactosylhydroxylysine glucosidase isoform h1 (human)

description: A protein-glucosylgalactosylhydroxylysine glucosidase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q32M88-1.