name: HLA-G specific inhibitory MHC class Ib receptor activity

description: Combining with a MHC class Ib molecule of the HLA-G subclass to mediate signaling that inhibits activation of a lymphocyte.


Testicular Myeloid Sarcoma

category: biolink:Disease biolink:DiseaseOrPhenotypicFeature biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing

description: A rare myeloid sarcoma that arises from the testis. At presentation the involvement is usually unilateral.


Phosphaturic mesenchymal tumor, benign

description: A phosphaturic mesenchymal tumor with benign histologic features.  It may recur locally but does not metastasize.  Complete excision is curative.


name: vertebral, cardiac, renal, and limb defects syndrome 3


name: congenital vertebral-cardiac-renal anomalies syndrome


name: vertebral, cardiac, renal, and limb defects syndrome 1


name: vertebral, cardiac, renal, and limb defects syndrome 2


NF-kappaB p50/p65 complex

category: biolink:CellularComponent biolink:AnatomicalEntity biolink:PhysicalEssence biolink:OrganismalEntity biolink:SubjectOfInvestigation biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: A heterodimer of NF-kappa B p50 and p65 subunits.


melatonin binding

category: biolink:MolecularActivity biolink:Occurrent biolink:OntologyClass biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: Binding to melatonin.


parakeratinized epithelium of gingiva

category: biolink:GrossAnatomicalStructure biolink:AnatomicalEntity biolink:PhysicalEssence biolink:OrganismalEntity biolink:SubjectOfInvestigation biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: A parakeratinized epithelium that is part of a gingiva.


gingival epithelium

description: A stratified squamous epithelium consisting of a basal layer; it is keratinized or parakeratinized[BTO].


name: androsterone dehydrogenase (A-specific) activity

description: Catalysis of the reaction: NAD(P)+ + androsterone = NAD(P)H + H+ + 5-alpha-androstane-3,17-dione. The reaction is A-specific (i.e. the pro-R hydrogen is transferred from the 4-position of reduced nicotinamide cofactor) with respect to NAD(P)+.


name: androsterone dehydrogenase (B-specific) activity

description: Catalysis of the reaction: NAD(P)+ + androsterone = NAD(P)H + H+ + 5-alpha-androstane-3,17-dione. The reaction is B-specific (i.e. the pro-S hydrogen is transferred from the 4-position of reduced nicotinamide cofactor) with respect to NAD(P)+.


name: positive regulation of very-low-density lipoprotein particle clearance

category: biolink:BiologicalProcess biolink:Occurrent biolink:OntologyClass biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: Any process that increases the frequency, rate or extent of very-low-density lipoprotein particle clearance.


age related macular degeneration 1

description: An age related macular degeneration associated with polymorphism in the hemicentin gene (HMCN1) on chromosome 1q25.3-q31.1.


name: negative regulation of protein targeting to vacuole involved in autophagy

description: Any process that stops, prevents or reduces the frequency, rate or extent of protein targeting to vacuole involved in autophagy.


name: negative regulation of protein targeting to vacuolar membrane

description: Any process that stops, prevents or reduces the frequency, rate or extent of protein targeting to vacuolar membrane.


name: negative regulation of axo-dendritic protein transport

description: Any process that stops, prevents or reduces the frequency, rate or extent of axo-dendritic protein transport.


name: negative regulation of endosome to plasma membrane protein transport

description: Any process that stops, prevents or reduces the frequency, rate or extent of endosome to plasma membrane protein transport.


name: negative regulation of post-translational protein targeting to membrane, translocation

description: Any process that stops, prevents or reduces the frequency, rate or extent of posttranslational protein translocation through the ER membrane.


name: negative regulation of protein insertion into mitochondrial outer membrane

description: Any process that stops, prevents or reduces the frequency, rate or extent of protein insertion into mitochondrial outer membrane.


name: snoRNA transcription by RNA polymerase III

description: The synthesis of small nucleolar RNA (snoRNA) from a DNA template by RNA polymerase III, originating at a type 2 RNA polymerase III promoter.


pollen tube reception

description: An interaction between the pollen tube, part of the male gametophyte, and the female gametophyte (typically the synergid cells), that results in the arrest of pollen tube growth, rupture of the pollen tube and the release of the sperm cells.


Jejunal Melanoma

description: A melanoma that arises from the jejunum.


Jejunal Carcinoma

description: A carcinoma that arises from the jejunum.


gravitaxis

description: The directed movement of a motile cell or organism in response to gravity.


negative gravitaxis

description: The directed movement of a motile cell or organism away from the source of gravity.


positive gravitaxis

description: The directed movement of a motile cell or organism towards the source of gravity.


African histoplasmosis

description: An disease or disorder caused by infection with Histoplasma capsulatum var. duboisii.


name: Histoplasma capsulatum infectious disease

description: An disease or disorder caused by infection with Histoplasma capsulatum.


histoplasmosis meningitis

description: An infectious meningitis caused by infection with Histoplasma capsulatum.


histoplasmosis retinitis

description: An retinitis caused by infection with Histoplasma capsulatum.


macular corneal dystrophy

description: Macular corneal dystrophy (MCD) is a rare, severe form of stromal corneal dystrophy characterized by bilateral ill-defined cloudy regions within a hazy stroma, and eventually severe visual impairment.


gelatinous drop-like corneal dystrophy

description: Gelatinous drop-like corneal dystrophy (GDCD) is a form of superficial corneal dystrophy characterized by multiple prominent milky-white gelatinous nodules beneath the corneal epithelium, and marked visual impairment.


Mounier-Kuhn syndrome

description: Mounier-Kuhn syndrome, also known as idiopathic tracheobronchomegaly, is a congenital disorder characterized by marked dilatation of the trachea and proximal bronchi that leads to impaired airway secretion clearance and recurrent lower respiratory tract infections.


SHG alpha-glucan phosphorylase activity

description: Catalysis of the reaction: hydrogenphosphate + a plant soluble heteroglycan = alpha-D-glucose 1-phosphate + a plant soluble heteroglycan.


genochondromatosis type 1

description: Genochondromatosis is characterized by chondromatosis, typically involving the clavicles, upper end of the humerus, and lower end of the femur. Lesions are bilateral and symmetrical. It has been described four patients from the same family and is transmitted as an autosomal dominant trait. Another disorder, genochondromatosis II, shows strong similarities to genochondromatosis but is characterized by the involvement of the short tubular bones and by normal clavicles. It has been described in one unrelated family. Genochondromatosis II may also be inherited as an autosomal dominant trait. Genochondromatosis has a benign clinical course.


genochondromatosis type 2

description: Genochondromatosis type 2 is a rare genetic bone development disorder characterized by normal clavicles and symmetrical generalized metaphyseal enchondromas particularly in the distal femur, proximal humerus, and bones of the wrists, hands, and feet. Lesions regress later in life with growth cartilage obliteration. Clinical examination is normal and the course of the disease is benign.


protein pupylation

description: The process in which a Pup protein is conjugated to a target protein via an isopeptide bond between the carboxy-terminus of Pup and the epsilon-amino group of a lysine residue of the target protein.


A 1-glycosyltriazole in which the glycosyl residue is specified as ribosyl.


sensory perception of slow pain

description: The series of events required for an organism to receive a slow pain stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. Slow pain is often subjectively described as an aching or throbbing pain; in humans, the signals from a slow pain stimulus are perceived and relayed along unmyelinated C fibers to the central nervous system, reaching their target in about 1 second. Slow pain is often associated with tissue destruction.


name: polyuridylation-dependent decapping of nuclear-transcribed mRNA

description: Cleavage of the 5'-cap of a nuclear-transcribed mRNA that has been modified by the enzymatic addition of a sequence of uridylyl residues (polyuridylation) at the 3' end.


facial nerve formation

description: The process that gives rise to the facial nerve. This process pertains to the initial formation of a structure from unspecified parts. This sensory and motor nerve supplies the muscles of facial expression and the expression and taste at the anterior two-thirds of the tongue. The principal branches are the superficial ophthalmic, buccal, palatine and hyomandibular. The main trunk synapses within pterygopalatine ganglion in the parotid gland and this ganglion then gives of nerve branches which supply the lacrimal gland and the mucous secreting glands of the nasal and oral cavities.


Stage IV Adult Hodgkin Lymphoma

description: Ann Arbor Classification: Stage IV: Diffuse or disseminated involvement of one or more extralymphatic organs, with or without associated lymph node involvement; or isolated extralymphatic organ involvement in the absence of adjacent regional lymph node involvement, but in conjunction with disease in distant site(s); or any involvement of the liver or bone marrow, lungs (other than by direct extension from another site), or cerebrospinal fluid.


name: Esophageal squamous cell carcinoma recurrent

description: An esophageal squamous cell carcinoma which has reappeared after a period of remission or after presumed treatment.


benign neoplasm of lacrimal gland

description: A benign neoplasm that involves the lacrimal gland.


lacrimal gland neoplasm

description: A neoplasm (disease) that involves the lacrimal gland.


lacrimal gland cancer

description: A malignant neoplasm involving the lacrimal gland.


description: Catalysis of the hydrolysis of terminal, non-reducing N-acetylmuramic residues.


ceratohyal-ventral hypohyal joint

description: Joint that articulates the ceratohyal and ventral hypohyal bones. Ceratohyal-ventral hypohyal joint is paired.


natural killer cell apoptotic process

description: Any apoptotic process in a natural killer cell, a lymphocyte that can spontaneously kill a variety of target cells without prior antigenic activation.


name: negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis

description: Any process that stops, prevents or reduces the frequency, rate or extent of Fc-gamma receptor signaling pathway involved in phagocytosis.


name: regulation of Fc-gamma receptor signaling pathway involved in phagocytosis

description: Any process that modulates the frequency, rate or extent of Fc-gamma receptor signaling pathway involved in phagocytosis.


name: positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis

description: Any process that activates or increases the frequency, rate or extent of Fc-gamma receptor signaling pathway involved in phagocytosis.


name: all-trans-beta-apo-10'-carotenal cleavage oxygenase activity

description: Catalysis of the reaction: 10'-apo-beta-carotenal + O2 = 13-apo-beta-carotenone + 4-methylocta-2,4,6-trienedial.


Stargardt disease 4

description: Any Stargardt disease in which the cause of the disease is a mutation in the PROM1 gene.


name: positive regulation of spontaneous neurotransmitter secretion

description: Any process that activates or increases the frequency, rate or extent of spontaneous neurotransmitter secretion.


leading edge of dendritic growth cone

description: That part of the dendritic growth cone which represents the distal part of the structure.


Sporadic Cylindroma

description: A cylindroma occurring as a solitary sporadic lesion.


interleukin-13 receptor binding

description: Binding to an interleukin-13 receptor.


interleukin-20 receptor binding

description: Binding to an interleukin-20 receptor.


interleukin-11 receptor binding

description: Binding to an interleukin-11 receptor.


CX3C chemokine receptor binding

description: Binding to a CX3C chemokine receptor.


name: granulocyte macrophage colony-stimulating factor receptor binding

description: Binding to a granulocyte macrophage colony-stimulating factor receptor.


XCR1 chemokine receptor binding

description: Binding to a XCR1 chemokine receptor.


CCR6 chemokine receptor binding

description: Binding to a CCR6 chemokine receptor.


interleukin-17 receptor binding

description: Binding to an interleukin-17 receptor.


name: granulocyte colony-stimulating factor receptor binding

description: Binding to a granulocyte colony-stimulating factor receptor.


interleukin-26 receptor binding

description: Binding to an interleukin-26 receptor.


CXCR6 chemokine receptor binding

description: Binding to a CXCR6 chemokine receptor.


interleukin-19 receptor binding

description: Binding to an interleukin-19 receptor.


interleukin-7 receptor binding

description: Binding to an interleukin-7 receptor.


interleukin-25 receptor binding

description: Binding to an interleukin-25 receptor.


interleukin-24 receptor binding

description: Binding to an interleukin-24 receptor.


interleukin-9 receptor binding

description: Binding to an interleukin-9 receptor.


CCR3 chemokine receptor binding

description: Binding to a CCR3 chemokine receptor.


CCR8 chemokine receptor binding

description: Binding to a CCR8 chemokine receptor.


CCR9 chemokine receptor binding

description: Binding to a CCR9 chemokine receptor.


name: brain-derived neurotrophic factor receptor binding

description: Binding to a brain-derived neurotrophic factor receptor.


interleukin-17E receptor binding

description: Binding to an interleukin-17E receptor.


CXCR2 chemokine receptor binding

description: Binding to a CXCR2 chemokine receptor.


CXCR5 chemokine receptor binding

description: Binding to a CXCR5 chemokine receptor.


interleukin-15 receptor binding

description: Binding to an interleukin-15 receptor.


interleukin-10 receptor binding

description: Binding to an interleukin-10 receptor.


CCR11 chemokine receptor binding

description: Binding to a CCR11 chemokine receptor.


interleukin-16 receptor binding

description: Binding to an interleukin-16 receptor.


interleukin-35 receptor binding

description: Binding to an interleukin-35 receptor.


interleukin-33 receptor binding

description: Binding to an interleukin-33 receptor.


CXCR1 chemokine receptor binding

description: Binding to a CXCR1 chemokine receptor.


CCR4 chemokine receptor binding

description: Binding to a CCR4 chemokine receptor.


interleukin-28 receptor binding

description: Binding to an interleukin-28 receptor.


interleukin-18 receptor binding

description: Binding to an interleukin-18 receptor.


interleukin-21 receptor binding

description: Binding to an interleukin-21 receptor.


neurotrophin TRKC receptor binding

description: Binding to a neurotrophin TRKC receptor.


CXCR4 chemokine receptor binding

description: Binding to a CXCR4 chemokine receptor.


arylalkyl acylamidase activity

description: Catalysis of the reaction: H2O + N-acetylarylalkylamine = acetate + arylalkylamine.


name: positive regulation of basophil differentiation

description: Any process that activates or increases the frequency, rate or extent of basophil differentiation.


name: protein-phycobiliviolin linkage via S-phycobiliviolin-L-cysteine

description: The linkage of the chromophore phycobiliviolin to phycoerythrocyanin via S-phycobiliviolin-L-cysteine.


protein-phycobiliviolin linkage

description: The linkage of the chromophore phycobiliviolin to phycoerythrocyanin.


name: neuron migration involved in amphid sensory organ dendrite retrograde extension

description: The directed, self-propelled movement of a neuron that contributes to the process of retrograde extension of a dendrite of a neuron in the amphid sensory organ.


name: Closed fracture of mandible, multiple sites

description: A traumatic break in two or more places in the mandible that does not involve a break in the adjacent skin.


name: Descending Colon Neuroendocrine Tumor G1

description: A well differentiated, low grade neuroendocrine neoplasm that arises from the descending colon. The mitotic count is less than 2 per 10 HPF and/or the Ki67 index is equal to or less than 2 percent.


name: fibroblast growth factor receptor signaling pathway involved in somitogenesis

category: biolink:Pathway biolink:OntologyClass biolink:BiologicalProcess biolink:Occurrent biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands that contributes to somitogenesis.


Elevated Alpha-Hydroxyglutarate

category: biolink:PhenotypicFeature biolink:DiseaseOrPhenotypicFeature biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing

description: A finding indicating elevated concentrations of alpha-hydroxyglutarate in a sample.


name: neutral amino acid, sodium:proton antiporter activity

description: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(in) + amino acid(out) + Na+(out) = H+(out) + amino acid(in) + Na+(in).


metal cation:proton antiporter activity

description: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: metal ion(in) + H+(out) = metal ion(out) + H+(in).


name: L-histidine, sodium:proton antiporter activity

description: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(in) + L-histidine(out) + Na+(out) = H+(out) + L-histidine(in) + Na+(in).


name: manganese:proton antiporter activity

description: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Mn2+(in) + H+(out) = Mn2+(out) + H+(in).


name: L-glutamine, sodium:proton antiporter activity

description: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(in) + L-glutamine(out) + Na+(out) = H+(out) + L-glutamine(in) + Na+(in).


name: zinc:proton antiporter activity

description: Enables the transfer of zinc from one side of a membrane to the other according to the reaction: H+(out) + Zn2+(in) = H+(in) + Zn2+(out).


name: sodium:proton antiporter activity involved in regulation of cardiac muscle cell membrane potential

description: Enables the transfer of a solute or solutes from one side of a cardiac muscle cell membrane to the other according to the reaction: Na+(out) + H+(in) = Na+(in) + H+(out). This transfer contributes to the regulation of the cardiac muscle cell plasma membrane potential.


name: lithium:proton antiporter activity

description: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Li+(in) + H+(out) = Li+(out) + H+(in).


name: L-asparagine, sodium:proton antiporter activity

description: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(in) + L-asparagine(out) + Na+(out) = H+(out) + L-asparagine(in) + Na+(in).


name: calcium:proton antiporter activity

description: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Ca2+(in) + H+(out) = Ca2+(out) + H+(in).


name: negative regulation of membrane hyperpolarization

description: Any process that stops, prevents or reduces the frequency, rate or extent of membrane hyperpolarization.


20q11.2 microdeletion syndrome

description: 20q11.2 microdeletion syndrome is a rare, genetic, syndromic intellectual disability characterized by psychomotor delay, hypotonia, feeding difficulties, failure to thrive, anomalies of the hands and feet (clinodactyly, camptodactyly, brachydactyly, feet malposition), and craniofacial dysmorphism. Associated prenatal growth retardation, and gastrointestinal, heart and eye anomalies have been reported.


D-galacturonate catabolic process

description: The chemical reactions and pathways resulting in the breakdown of D-galacturonate, the D-enantiomer of galacturonate, the anion of galacturonic acid.


D-galacturonate metabolic process

description: The chemical reactions and pathways involving D-galacturonate, the D-enantiomer of galacturonate, the anion of galacturonic acid. D-galacturonic acid is a component of plant gums and bacterial cell walls.


D-galacturonate biosynthetic process

description: The chemical reactions and pathways resulting in the formation of D-galacturonate, the D-enantiomer of galacturonate, the anion of galacturonic acid.


name: Resectable Clear Cell Renal Cell Carcinoma

description: Clear cell renal cell carcinoma that is amenable to surgical resection.


Resectable Renal Cell Carcinoma

description: Renal cell carcinoma that is amenable to surgical resection.


esophagus squamous epithelium

description: A squamous epithelium that is part of a esophagus.


name: negative regulation of primary miRNA processing

description: Any process that stops, prevents or reduces the frequency, rate or extent of primary microRNA processing.


target-directed miRNA degradation

description: The process in which a miRNA is targeted for degradation by a non-coding RNA or mRNA. The binding of an RNA to a target miRNA within a RISC complex results in either ubiquitin-mediated degradation of AGO protein or the displacement of the 3' end of the miRNA, exposing it to nucleases.


positive regulation of miRNA processing

description: Any process that activates or increases the frequency, rate or extent of microRNA processing.


name: positive regulation of pre-miRNA processing

description: Any process that activates or increases the frequency, rate or extent of pre-microRNA processing.


name: positive regulation of primary miRNA processing

description: Any process that activates or increases the frequency, rate or extent of primary microRNA processing.


urethral calculus

description: A concretion in the urethra.


retinitis pigmentosa 42

description: Any retinitis pigmentosa in which the cause of the disease is a mutation in the KLHL7 gene.


name: positive regulation of barbed-end actin filament capping

description: Any process that activates or increases the frequency, rate or extent of barbed-end actin filament capping.


TDP-43 proteinopathy

description: Disease characterized by the presence of abnormally phosphorylated, ubiquitinated, and cleaved DNA-binding protein TDP-43 in affected brain and spinal cord. Inclusions of the pathologic protein in neurons and glia, without the presence of AMYLOID, is the major feature of these conditions, thus making these proteinopathies distinct from most other neurogenerative disorders in which protein misfolding leads to brain amyloidosis. Both frontotemporal lobar degeneration and AMYOTROPHIC LATERAL SCLEROSIS exhibit this common method of pathogenesis and thus they may represent two extremes of a continuous clinicopathological spectrum of one disease.


name: symbiont-mediated suppression of host chemokine signal transduction pathway

description: A process in which a symbiont interferes with, inhibits or disrupts a chemokine signaling pathway, a G protein-coupled receptor signal transduction pathway activated by a chemokine. The host is defined as the larger of the organisms involved in a symbiotic interaction.


cervicofacial actinomycosis

description: A form of actinomycosis characterized by slow-growing inflammatory lesions of the lymph nodes that drain the mouth (lumpy jaw), reddening of the overlying skin, and intraperitoneal abscesses.


name: positive regulation of high voltage-gated calcium channel activity

description: Any process that activates or increases the frequency, rate or extent of high voltage-gated calcium channel activity.


name: positive regulation of hepatic stellate cell migration

description: Any process that increases the frequency, rate or extent of hepatic stellate cell migration.


4p16.3 microduplication syndrome

description: 4p16.3 microduplication syndrome is a rare genetic syndrome that results from the partial duplication of the short arm of chromosome 4. It has a highly variable phenotype, principally characterized by psychomotor and language delay, seizures and dysmorphic features such as high forehead with frontal bossing, hypertelorism, prominent glabella, long narrow palpebral fissures, low set ears and short neck. Eye abnormalities (glaucoma, irregular iris pigmentation, hyperopia) have also been reported.


name: positive regulation of neutrophil activation

description: Any process that activates or increases the frequency, rate or extent of neutrophil activation.


name: developmental and epileptic encephalopathy, 62


Intraocular Infection

description: Infection within the eye.


Fungal endophthalmitis

description: Inflammation of the lining of the ocular cavities, which results from a fungal infection.


parasitic endophthalmitis

description: Infection of the epicondyles by a parasite.


cellular response to L-glutamate

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-glutamate(1-) stimulus.


name: establishment of latency as a circular episome

description: A process by which a virus establishes a latent state within its host as an episome, where the viral genome remains silent in the cytoplasm or nucleus as a circular structure.


establishment of episomal latency

description: A process by which a virus establishes a latent state within its host as an episome, where the viral genome remains silent in the cytoplasm or nucleus as a distinct genetic entity.


name: establishment of latency as a linear episome

description: A process by which a virus establishes a latent state within its host as an episome, where the viral genome remains silent in the cytoplasm or nucleus as linear structure.


caudate lobe hepatic sinusoid

description: A hepatic sinusoid that is part of a caudate lobe of liver.


name: peroxisome membrane class-1 targeting sequence binding

description: Binding to a class I peroxisomal membrane targeting sequence, any of several sequences of amino acids within a protein that can act as a signal for the localization of the protein into the peroxisome membrane in a PEX19-dependent manner.


autoimmune vasculitis

description: An autoimmune form of vasculitis.


rheumatoid vasculitis

description: Necrotizing VASCULITIS of small and medium size vessels, developing as a complication in RHEUMATOID ARTHRITIS patients. It is characterized by peripheral vascular lesions, cutaneous ulcers, peripheral gangrene, and mononeuritis multiplex.


name: positive regulation of estrogen secretion

description: Any process that activates or increases the frequency, rate or extent of estrogen secretion.


Toc complex

description: Protein translocon complex at the chloroplast outer membrane.


name: Benign Epithelial Melanoses of the Conjunctiva

description: A group of benign, non-neoplastic lesions in the conjunctiva characterized by increased production of melanin without proliferation of conjunctival melanocytes.


Recurrent Breast Acinic Cell Carcinoma

description: The reemergence of acinic cell breast carcinoma after a period of remission.


Branch of abdominal aorta

category: biolink:AnatomicalEntity biolink:PhysicalEssence biolink:OrganismalEntity biolink:SubjectOfInvestigation biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: An arterial segment arising from the abdominal aorta that supplies blood to the abdominal organs, other structures, genitalia and the lower limbs. The aortic branches include terminal branches called the common iliac arteries, the celiac artery, the superior mesenteric artery, the inferior mesenteric artery, the renal arteries, the suprarenal arteries, the testicular (internal spermatic) arteries, the ovarian arteries, the inferior phrenic arteries, lumbar arteries and the middle sacral artery.


left common iliac artery

description: The common iliac artery situated on the left side of the body.


common iliac artery

description: The common iliac arteries are two large arteries, about 4cm long in adults but more than a centimetre in diameter, that originate from the aortic bifurcation. The arteries run inferolaterally, along the medial border of the psoas muscles to the pelvic brim, where they bifurcate into the external iliac artery and internal iliac artery. The common iliac artery, and all of its branches, exist as paired structures (that is to say, there is one on the left side and one on the right). The distribution of the common iliac artery is basically the pelvis and lower limb on the corresponding side. Both common iliac arteries are accompanied along their course by common iliac veins. [WP,unvetted].


iliolumbar artery

description: The iliolumbar artery is a branch of the posterior trunk of the internal iliac artery. [WP,unvetted].


left testicular artery

description: A testicular artery that supplies a left testicle.


spermatic artery

description: A branch of the abdominal aorta that supplies oxygenated blood to the testis.


phrenic artery

description: An artery that supplies the diaphragm.


left gastric artery

description: An artery that arises from the celiac artery and supplies the stomach.


right testicular artery

description: A testicular artery that supplies a right testicle.


mesenteric artery

description: Arteries which arise from the abdominal aorta and distribute to most of the intestines.


suprarenal artery

description: Artery that supplies blood to the adrenal glands.


ovarian artery

description: An artery that supplies an ovary.


right renal artery

description: Renal artery that supplies the right kidney.


lumbar artery

description: The lumbar arteries are in series with the intercostals. They are usually four in number on either side, and arise from the back of the aorta, opposite the bodies of the upper four lumbar vertebrC&. A fifth pair, small in size, is occasionally present: they arise from the middle sacral artery. They run lateralward and backward on the bodies of the lumbar vertebrC&, behind the sympathetic trunk, to the intervals between the adjacent transverse processes, and are then continued into the abdominal wall. The arteries of the right side pass behind the inferior vena cava, and the upper two on each side run behind the corresponding crus of the diaphragm. The arteries of both sides pass beneath the tendinous arches which give origin to the Psoas major, and are then continued behind this muscle and the lumbar plexus. They now cross the Quadratus lumborum, the upper three arteries running behind, the last usually in front of the muscle. At the lateral border of the Quadratus lumborum they pierce the posterior aponeurosis of the Transversus abdominis and are carried forward between this muscle and the Obliquus internus. They anastomose with the lower intercostal, the subcostal, the iliolumbar, the deep iliac circumflex, and the inferior epigastric arteries.


left renal artery

description: Renal artery that supplies the left kidney.


inferior suprarenal artery

description: Each renal artery gives off some small inferior suprarenal branches to the suprarenal gland, the ureter, and the surrounding cellular tissue and muscles. [WP,unvetted].


Accessory Renal Artery

description: An additional renal artery originating from the aorta. Accessory renal arteries are found in 26-30% of humans.


superior suprarenal artery

description: Each (left and right) superior suprarenal artery is a branch of the inferior phrenic artery on that side of the body. The left and right phrenic arteries supply the diaphragm, and come off the aorta. [WP,unvetted].


right common iliac artery

description: The common iliac artery situated on the right side of the body.


iliac artery

description: Any of the arteries that arise from a bifurcation of the aorta supplying the pelvic or abdomen. Examples: Common iliac artery, External iliac artery, Internal iliac artery.


name: immunoskeletal dysplasia with neurodevelopmental abnormalities


cranial nodular fasciitis

description: A rare self-limiting, rapidly growing, non-encapsulated benign neoplasm that arises from the cranium. This is an osteolytic lesion. It is characterized by the presence of plump spindle-shaped fibroblasts, multinucleated osteoclast-like giant cells, chronic inflammatory infiltrate, red blood cell extravasation, and high mitotic activity.


name: positive regulation of syringal lignin catabolic process

description: Any process that activates or increases the frequency, rate or extent of syringal lignin catabolic process.


Stage V Kidney Wilms Tumor

description: Wilms tumor that affects both kidneys at the same time. The tumor in each kidney is staged separately (National Wilms Tumor Study Group Staging System)


Kv4.3-KChIP1 channel complex

description: A voltage-gated potassium channel complex that contains the Kv channel interacting protein KChIP1 associated with the channel via interaction with the Kv alpha subunit 4.3.


name: type IV site-specific deoxyribonuclease activity

description: Catalysis of the endonucleolytic cleavage of DNA in a site specific manner. Cleavage is dependent on the presence of a specific recognition site in the DNA which must be modified (e.g. methylated, hydroxymethylated, glucosyl-hydroxymethylated).


name: negative regulation of nucleobase-containing compound metabolic process

description: Any cellular process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids.


name: negative regulation of single-strand break repair via homologous recombination

description: Any process that stops, prevents or reduces the frequency, rate or extent of single-strand break repair via homologous recombination.


name: negative regulation of pyruvate kinase activity

description: Any process that stops, prevents or reduces the frequency, rate or extent of pyruvate kinase activity.


name: negative regulation of poly(A)-specific ribonuclease activity

description: Any process that stops, prevents or reduces the frequency, rate or extent of poly(A)-specific ribonuclease activity.


name: negative regulation of double-strand break repair via single-strand annealing

description: Any process that stops, prevents or reduces the frequency, rate or extent of double-strand break repair via single-strand annealing.


name: negative regulation of exoribonuclease activity

description: Any process that stops, prevents or reduces the frequency, rate or extent of exoribonuclease activity.


name: negative regulation of transcription elongation by RNA polymerase I

description: Any process that stops, prevents or reduces the frequency, rate or extent of transcription elongation mediated by RNA polymerase I.


name: negative regulation of termination of RNA polymerase I transcription

description: Any process that stops, prevents or reduces the frequency, rate or extent of termination of RNA polymerase I transcription.


name: negative regulation of reciprocal meiotic recombination

description: Any process that decreases the frequency, rate or extent of recombination during meiosis. Reciprocal meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate.


name: negative regulation of transcription by transcription factor catabolism

description: Any process that stops, prevents, or reduces the frequency, rate or extent of DNA-dependent transcription using a mechanism that involves the catabolism of a sequence-specific DNA-binding transcription factor by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.


name: negative regulation of termination of DNA-templated transcription

description: Any process that decreases the rate, frequency or extent of DNA-dependent transcription termination, the process in which transcription is completed; the formation of phosphodiester bonds ceases, the RNA-DNA hybrid dissociates, and RNA polymerase releases the DNA.


name: negative regulation of ribosomal protein gene transcription from RNA polymerase II promoter in response to nutrient levels

description: Any process that decreases the frequency, rate or extent of the synthesis of RNA from ribosomal protein genes by RNA polymerase II, originating at an RNA polymerase II promoter, as a result of a stimulus reflecting the presence, absence, or concentration of nutrients.


negative regulation of DNA ligation

description: Any process that stops, prevents, or reduces the frequency, rate or extent of DNA ligation, the re-formation of a broken phosphodiester bond in the DNA backbone, carried out by DNA ligase.


name: negative regulation of protection from non-homologous end joining at telomere

description: Any process that stops, prevents or reduces the frequency, rate or extent of protection from non-homologous end joining at telomere.


name: replication fork arrest at mating type locus

description: A process that impedes the progress of the DNA replication fork at natural replication fork pausing sites within the mating type locus.


name: negative regulation of endoribonuclease activity

description: Any process that decreases the rate, frequency or extent of the catalysis of the hydrolysis of ester linkages within ribonucleic acid by creating internal breaks.


name: negative regulation of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination

description: Any process that stops, prevents or reduces the frequency, rate or extent of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination.


name: negative regulation of apoptotic DNA fragmentation

description: Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic DNA fragmentation.


name: negative regulation of reverse transcription

description: Any process that stops, prevents or reduces the frequency, rate or extent of reverse transcription.


name: negative regulation of error-prone translesion synthesis

description: Any process that stops, prevents or reduces the frequency, rate or extent of error-prone translesion synthesis.


name: negative regulation of ribosomal protein gene transcription from RNA polymerase II promoter in response to stress

description: Any process that decreases the frequency, rate or extent of the synthesis of RNA from ribosomal protein genes by RNA polymerase II, originating at an RNA polymerase II promoter, as a result of a disturbance in organismal or cellular homeostasis.


name: negative regulation of mitotic recombination-dependent replication fork processing

description: Any process that inhibits or decreases the rate of mitotic recombination-dependent replication fork processing. Suppression of recombination at replication forks is necessary to prevent template switching.


name: negative regulation of mitotic DNA replication initiation from late origin

description: Any process that stops, prevents or reduces the frequency, rate or extent of firing from a late origin of replication involved in mitotic DNA replication.


name: negative regulation of telomere single strand break repair

description: Any process that stops, prevents or reduces the frequency, rate or extent of telomere single strand break repair.


name: negative regulation of DNA ligase activity

description: Any process that stops, prevents or reduces the frequency, rate or extent of DNA ligase activity.


name: negative regulation of pyrimidine nucleotide biosynthetic process

description: Any process that stops, prevents or reduces the frequency, rate or extent of pyrimidine nucleotide biosynthetic process.


name: carbon catabolite repression of transcription by galactose

description: A transcription regulation process in which the presence of galactose that leads to a decrease in the frequency, rate, or extent of transcription of specific genes involved in the metabolism of other carbon sources. Carbon catabolite repression is a mechanism of genetic regulation which the accumulation of catabolites of one substance in the cell represses the formation of enzymes that contribute to the catabolism of other substances.


name: negative regulation of mRNA cis splicing, via spliceosome

description: Any process that stops, prevents or reduces the frequency, rate or extent of mRNA cis splicing, via spliceosome.


name: negative regulation of meiotic DNA double-strand break formation

description: Any process that stops, prevents or reduces the frequency, rate or extent of meiotic DNA double-strand break formation.


telomerase RNA stabilization

description: Prevention of degradation of telomerase RNA (TERC) molecules.


name: negative regulation of DNA strand resection involved in replication fork processing

description: Any process that stops, prevents, or reduces the frequency, rate or extent of DNA strand resection involved in replication fork processing.


name: negative regulation of single strand break repair

description: Any process that stops, prevents or reduces the frequency, rate or extent of single strand break repair.


name: negative regulation of miRNA metabolic process

description: Any process that stops, prevents or reduces the frequency, rate or extent of miRNA metabolic process.


name: negative regulation of DNA primase activity

description: Any process that stops, prevents or reduces the frequency, rate or extent of DNA primase activity.


name: negative regulation of telomerase RNA reverse transcriptase activity

description: Any process that stops, prevents or reduces the frequency, rate or extent of telomerase RNA reverse transcriptase activity.


name: negative regulation of type III site-specific deoxyribonuclease activity

description: Any process that stops or reduces the rate of type III restriction endodeoxyribonuclease activity.


name: negative regulation of deadenylation-dependent decapping of nuclear-transcribed mRNA

description: Any process that stops, prevents, or reduces the frequency, rate or extent of deadenylation-dependent decapping of nuclear-transcribed mRNA.


name: negative regulation of nuclear-transcribed mRNA catabolic process, meiosis-specific transcripts

description: Any process that stops, prevents or reduces the frequency, rate or extent of selective degradation of meiosis-specific nuclear transcribed transcripts during vegetative growth, by a mechanism that requires determinant of selective removal (DSR) sequences in the targeted mRNAs and involves a YTH family protein.


name: negative regulation of DNA amplification

description: Any process that stops, prevents or reduces the frequency, rate or extent of DNA amplification.


name: negative regulation of telomeric loop disassembly

description: Any process that stops, prevents or reduces the frequency, rate or extent of telomeric loop disassembly.


replication fork arrest at tRNA locus

description: A process that impedes the progress of the DNA replication fork at natural replication fork pausing sites within the eukaryotic tRNA transcription unit.


name: negative regulation of snRNA transcription by RNA polymerase II

description: Any process that stops, prevents or reduces the frequency, rate or extent of snRNA transcription mediated by RNA polymerase II.


name: negative regulation of mitotic cell cycle DNA replication

description: Any process that stops, prevents or reduces the frequency, rate or extent of mitotic cell cycle DNA replication.


name: negative regulation of RNA metabolic process

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving RNA.


name: negative regulation of exodeoxyribonuclease activity

description: Any process that stops, prevents or reduces the frequency, rate or extent of exodeoxyribonuclease activity.


name: negative regulation of telomere maintenance in response to DNA damage

description: Any process that stops, prevents or reduces the frequency, rate or extent of telomere maintenance in response to DNA damage.


name: negative regulation of nuclear-transcribed mRNA poly(A) tail shortening

description: Any process that decreases the frequency, rate or extent of poly(A) tail shortening of a nuclear-transcribed mRNA. Poly(A) tail shortening is the decrease in length of the poly(A) tail of an mRNA from full length to an oligo(A) length.


inactivation of recombination (HML)

description: The inactivation of recombination at sequences around a mating type donor locus, with the consequence that the other donor is the only one available for mating type switching; exemplified by the HML locus and surrounding sequences on Chromosome III in Saccharomyces cerevisiae.


name: negative regulation of mRNA modification

description: Any process that decreases the rate, frequency, or extent of the covalent alteration of one or more nucleotides within an mRNA molecule to produce an mRNA molecule with a sequence that differs from that coded genetically.


name: negative regulation of type I site-specific deoxyribonuclease activity

description: Any process that stops or reduces the rate of type I restriction endodeoxyribonuclease activity.


name: negative regulation of mating-type specific transcription, DNA-templated

description: Any mating-type specific process that stops, prevents or reduces the rate of cellular DNA-templated transcription.


name: negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

description: Any process that stops, prevents or reduces the frequency, rate or extent of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay.


name: nitrogen catabolite repression of transcription from RNA polymerase II promoter

description: A transcription regulation process in which the presence of one nitrogen source leads to a decrease in the frequency, rate, or extent of transcription, from an RNA polymerase II promoter, of specific genes involved in the metabolism of other nitrogen sources.


name: negative regulation of type II site-specific deoxyribonuclease activity

description: Any process that stops or reduces the rate of type II restriction endodeoxyribonuclease activity.


name: negative regulation of endodeoxyribonuclease activity

description: Any process that stops or reduces the rate of endodeoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid by creating internal breaks.


name: negative regulation of DNA-templated DNA replication initiation

description: Any process that stops, prevents, or reduces the frequency, rate or extent of initiation of DNA-dependent DNA replication.


name: negative regulation of type IV site-specific deoxyribonuclease activity

description: Any process that stops or reduces the rate of type IV restriction endodeoxyribonuclease activity.


name: negative regulation of DNA recombination at centromere

description: Any process that stops, prevents, or reduces the frequency, rate or extent of genetic recombination at the centromere.


negative regulation of mismatch repair

description: Any process that stops, prevents, or reduces the frequency, rate or extent of mismatch repair.


replication fork arrest

description: Any process that stops, prevents, or reduces the frequency, rate or extent of DNA replication by impeding the progress of the DNA replication fork. Replication fork arrest is one of the 'quality control' processes ensuring that DNA-dependent DNA replication occurs correctly. DNA replication fork arrest during DNA-dependent DNA replication is not known to occur outside of cases where a replication error needs to be prevented or corrected.


name: negative regulation of transcription from RNA polymerase II promoter by a nonfermentable carbon source

description: A transcription regulation process in which the presence of a nonfermentable carbon source leads to a decrease of the frequency, rate, or extent of transcription, from an RNA polymerase II promoter, of specific genes involved in the metabolism of other carbon sources.


name: negative regulation of telomere maintenance via recombination

description: Any process that stops, prevents, or reduces the frequency, rate or extent of a recombinational process involved in the maintenance of proper telomeric length.


name: negative regulation of telomeric D-loop disassembly

description: Any process that stops, prevents or reduces the frequency, rate or extent of telomeric D-loop disassembly.


name: negative regulation of ribosomal protein gene transcription by RNA polymerase II

description: Any process that decreases the frequency, rate or extent of the synthesis of RNA from ribosomal protein genes mediated by RNA polymerase II.


name: negative regulation of mitochondrial mRNA catabolic process

description: Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrial mRNA catabolic process.


tRNA stabilization

description: Prevention of degradation of tRNA molecules.


name: negative regulation of deoxyribonuclease activity

description: Any process that stops or reduces the rate of deoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid.


name: negative regulation of glycolytic process through fructose-6-phosphate

description: Any process that stops, prevents or reduces the frequency, rate or extent of glycolytic process through fructose-6-phosphate.


name: negative regulation of DNA replication initiation involved in plasmid copy number maintenance

description: Any process that decreases the frequency, rate or extent of initiation of plasmid DNA replication that contributes to copy number maintenance.


name: negative regulation of mitotic DNA replication initiation

description: Any process that stops, prevents or reduces the frequency, rate or extent of DNA replication initiation involved in mitotic DNA replication.


name: negative regulation of restriction endodeoxyribonuclease activity

description: Any process that stops or reduces the rate of a restriction endodeoxyribonuclease activity, the catalysis of endonucleolytic cleavage of DNA in a site-specific manner, resulting in double-strand breaks.


name: negative regulation of miRNA catabolic process

description: Any process that stops, prevents or reduces the frequency, rate or extent of miRNA catabolic process.


name: negative regulation of exonuclease activity

description: Any process that stops, prevents or reduces the frequency, rate or extent of exonuclease activity.


name: carbon catabolite repression of transcription from RNA polymerase II promoter

description: A transcription regulation process in which the presence of one carbon source leads to a decrease in the frequency, rate, or extent of transcription, from an RNA polymerase II promoter, of specific genes involved in the metabolism of other carbon sources.


name: negative regulation of initiation of premeiotic DNA replication

description: Any process that stops, prevents or reduces the frequency, rate or extent of initiation of premeiotic DNA replication.


name: negative regulation of DNA-directed DNA polymerase activity

description: Any process that stops, prevents or reduces the frequency, rate or extent of DNA-directed DNA polymerase activity.


name: negative regulation of tRNA catabolic process

description: Any process that stops, prevents or reduces the frequency, rate or extent of tRNA catabolic process.


name: replication fork arrest involved in DNA replication termination

description: A replication fork arrest process that contributes to the termination of DNA replication.


replication fork arrest at rDNA repeats

description: A process that impedes the progress of the DNA replication fork at natural replication fork pausing sites within the eukaryotic rDNA repeat spacer.


negative regulation of strand invasion

description: Any process that decreases the rate, frequency or extent of strand invasion. Strand invasion is the process in which the nucleoprotein complex (composed of the broken single-strand DNA and the recombinase) searches and identifies a region of homology in intact duplex DNA. The broken single-strand DNA displaces the like strand and forms Watson-Crick base pairs with its complement, forming a duplex in which each strand is from one of the two recombining DNA molecules.


name: negative regulation of DNA-templated transcription

description: Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.


name: negative regulation of termination of RNA polymerase II transcription

description: Any process that stops, prevents or reduces the frequency, rate or extent of termination of RNA polymerase II transcription.


name: nitrogen catabolite repression of transcription

description: A transcription regulation process in which the presence of one nitrogen source leads to a decrease in the frequency, rate, or extent of transcription of specific genes involved in the metabolism of other nitrogen sources.


name: negative regulation of ribonuclease activity

description: Any process that decreases the rate, frequency, or extent of ribonuclease activity, catalysis of the hydrolysis of phosphodiester bonds in chains of RNA.


name: negative regulation of double-strand break repair via break-induced replication

description: Any process that stops, prevents or reduces the frequency, rate or extent of double-strand break repair via break-induced replication.


name: negative regulation of termination of RNA polymerase II transcription, poly(A)-coupled

description: Any process that stops, prevents or reduces the frequency, rate or extent of termination of RNA polymerase II transcription, poly(A)-coupled.


name: negative regulation of base-excision repair

description: Any process that stops, prevents or reduces the frequency, rate or extent of base-excision repair.


name: negative regulation of RNA polymerase III activity

description: Any process that stops, prevents or reduces the frequency, rate or extent of RNA polymerase III activity.


name: negative regulation of ribosomal protein gene transcription from RNA polymerase II promoter in response to chemical stimulus

description: Any process that decreases the frequency, rate or extent of the synthesis of RNA from ribosomal protein genes by RNA polymerase II, originating at an RNA polymerase II promoter, as a result of a chemical stimulus.


name: carbon catabolite repression of transcription from RNA polymerase II promoter by galactose

description: Any process involving galactose that stops, prevents or reduces the rate of transcription from an RNA polymerase II promoter.


transcription antitermination

description: A positive regulation of gene expression mechanism that allows RNA polymerase to continue transcription beyond a termination site, thus allowing expression of downstream genes under specific conditions.


name: negative regulation of RNA biosynthetic process

description: Any process that stops, prevents or reduces the frequency, rate or extent of RNA biosynthetic process.


detection of salicylic acid stimulus

description: The series of events in which a salicylic acid stimulus is received by a cell and converted into a molecular signal.


name: cellular response to salicylic acid stimulus

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a salicylic acid stimulus.


name: thrombocytopenia 12 with or without myopathy


name: osmosensory signaling pathway via Sho1 osmosensor

description: The series of molecular signals generated in response to osmotic change, as mediated through a Sho1 osmosensor system.


osmosensory signaling pathway

description: The series of molecular signals initiated in response to osmotic change.


name: osmosensory signaling via phosphorelay pathway

description: The series of molecular signals generated in response to osmotic change, as mediated through a phosphorelay system. In S.cerevisiae, the osmosensor is the histidine kinase Sln1.


upper aerodigestive tract neoplasm

description: Soft tissue tumors or cancer arising from the mucosal surfaces of the lip; oral cavity; pharynx; larynx; and cervical esophagus. Other sites included are the nose and paranasal sinuses; salivary glands; thyroid gland and parathyroid glands; and melanoma and non-melanoma skin cancers of the head and neck. (from Holland et al., Cancer Medicine, 4th ed, p1651)


name: Adenocarcinoma in multiple adenomatous polyps

description: Adenocarcinomas developing in gastrointestinal tract adenomas in patients with multiple adenomatous polyps.


name: Adenocarcinoma in adenomatous polyposis coli

description: Adenocarcinomas developing in colorectal adenomas in patients with a history of adenomatous polyposis coli. The mean age of development of adenocarcinoma is about 40 years.


alcoholic psychosis

description: A group of mental disorders associated with organic brain damage and caused by poisoning from alcohol.


childhood parosteal osteosarcoma

description: A low grade malignant bone-forming mesenchymal neoplasm arising from the surface of the bone. It occurs in childhood and usually affects the distal posterior femur, the proximal tibia, and proximal humerus. Painless swelling is the usual clinical sign. The prognosis is usually excellent.


peripheral osteosarcoma

description: A usually aggressive malignant bone-forming mesenchymal neoplasm arising from the surface of the bone.


high grade surface osteosarcoma

description: A usually aggressive high grade malignant bone-forming mesenchymal neoplasm arising from the surface of the bone.


Childhood Periosteal Osteosarcoma

description: A periosteal osteosarcoma occurring in childhood.


periosteal osteogenic sarcoma

description: An intermediate grade malignant bone-forming mesenchymal neoplasm with chondroblastic differentiation. It arises from the surface of the bone and affects the diaphysis or diaphyseal- metaphyseal portion of the long bones. A painless mass or swelling is the most common clinical sign. It is associated with a better prognosis than conventional osteosarcoma.


juxtacortical osteosarcoma

description: A low grade malignant bone-forming mesenchymal neoplasm arising from the surface of the bone. It usually affects the distal posterior femur, the proximal tibia, and proximal humerus. Painless swelling is the usual clinical sign. Most patients are young adults and the prognosis is usually excellent.


medulla oblongata formation

description: The process that gives rise to the medulla oblongata. This process pertains to the initial formation of a structure from unspecified parts. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate.


name: calmodulin-activated 3',5'-cyclic-AMP phosphodiesterase activity

description: Catalysis of the reactions: nucleoside 3',5'-cyclic AMP + H2O = AMP + H+; this activity is activated by binding to calcium-bound calmodulin.


name: D-tagatose 6-phosphate catabolic process

description: The chemical reactions and pathways resulting in the breakdown of a D-tagatose 6-phosphate.


deoxycytidine catabolic process

description: The chemical reactions and pathways resulting in the breakdown of deoxycytidine, 2-deoxyribosylcytosine, one of the four major nucleosides of DNA.


chitobiose catabolic process

description: The chemical reactions and pathways resulting in the breakdown of any chitobiose, a family of compounds derived from chitin and based on the structure of D-glucosaminyl-(1->4)-D-glucosamine.


N-acetylglucosamine catabolic process

description: The chemical reactions and pathways resulting in the breakdown of N-acetylglucosamine. The D isomer is a common structural unit of glycoproteins in plants, bacteria and animals; it is often the terminal sugar of an oligosaccharide group of a glycoprotein.


glycopeptide catabolic process

description: The chemical reactions and pathways resulting in the breakdown of glycopeptides, a compound in which carbohydrate is covalently attached to an oligopeptide composed of residues of L and/or D-amino acids. The term usually denotes a product of proteolytic degradation of a glycoprotein but includes glycated peptide.


butirosin catabolic process

description: The chemical reactions and pathways resulting in the breakdown of butirosin.


name: anthocyanin-containing compound catabolic process

description: The chemical reactions and pathways resulting in the breakdown of anthocyanins, any member of a group of intensely colored soluble glycosides of anthocyanidins.


amino disaccharide catabolic process

description: The chemical reactions and pathways resulting in the breakdown of any amino disaccharide, a disaccharide having one or more substituted or unsubstituted amino groups in place of hydroxy groups at unspecified positions.


gentamycin catabolic process

description: The chemical reactions and pathways resulting in the breakdown of gentamycin.


paromomycin catabolic process

description: The chemical reactions and pathways resulting in the breakdown of paromomycin.


description: The chemical reactions and pathways resulting in the breakdown of sophorosyloxydocosanoate, 13-sophorosyloxydocosanoate 6',6''-diacetate.


name: pyrimidine deoxyribonucleoside catabolic process

description: The chemical reactions and pathways resulting in the breakdown of any one of a family of organic molecules consisting of a pyrimidine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside).


name: 2-deoxyribose 1-phosphate catabolic process

description: The chemical reactions and pathways resulting in the breakdown of deoxyribose 1-phosphate, the phosphorylated sugar 1-phospho-2-deoxyribose.


deoxyuridine catabolic process

description: The chemical reactions and pathways resulting in the breakdown of deoxyuridine, 2-deoxyribosyluracil, one of the four major nucleosides of DNA.


O-sialoglycoprotein catabolic process

description: The chemical reactions and pathways resulting in the breakdown of O-sialoglycoproteins, glycoproteins which contain sialic acid as one of their carbohydrates. They are often found on or in the cell or tissue membranes and participate in a variety of biological activities.


galactosylceramide catabolic process

description: The chemical reactions and pathways resulting in the breakdown of galactosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of galactose by a ceramide group.


description: The chemical reactions and pathways resulting in the breakdown of poly-N-acetyllactosamine, a carbohydrate composed of N-acetyllactosamine repeats (Gal-beta-1,4-GlcNAc-beta-1,3)n.


amylopectin catabolic process

description: The chemical reactions and pathways resulting in the breakdown of an amylopectin.


glucuronoside catabolic process

description: The chemical reactions and pathways resulting in the breakdown of glucuronosides, compound composed of a hydroxy compound linked to a glucuronate residue.


galactosaminoglycan catabolic process

description: The chemical reactions and pathways resulting in the breakdown of galactosaminoglycans, any of a group of polysaccharides that contain amino sugars derived from the galactose.


lincomycin catabolic process

description: The chemical reactions and pathways resulting in the breakdown of lincomycin.


neomycin catabolic process

description: The chemical reactions and pathways resulting in the breakdown of neomycin.


S-glycoside catabolic process

description: The chemical reactions and pathways resulting in the breakdown of S-glycosides, any compound in which a glycosyl group has been substituted into a thiol group.


lipoteichoic acid catabolic process

description: The chemical reactions and pathways resulting in the breakdown of lipoteichoic acid, which is a major component of the cell wall of gram-positive bacteria and typically consists of a chain of glycerol-phosphate repeating units linked to a glycolipid anchor.


lipopolysaccharide catabolic process

description: The chemical reactions and pathways resulting in the breakdown of lipopolysaccharides, any of a group of related, structurally complex components of the outer membrane of Gram-negative bacteria.


kanamycin catabolic process

description: The chemical reactions and pathways resulting in the breakdown of kanamycin.


diacetylchitobiose catabolic process

description: The chemical reactions and pathways resulting in the breakdown of diacetylchitobiose into simpler products.


deoxyinosine catabolic process

description: The chemical reactions and pathways resulting in the breakdown of deoxyinosine, hypoxanthine deoxyriboside.


name: diacetylchitobiose catabolic process to glucosamine and acetate

description: The pathway resulting in the breakdown of diacetylchitobiose into simpler products, including glucosamine and glucosamine. The catabolism proceeds by the deacetylation of diacetylchitobiose, producing acetate and GlcN-GlcNAc; the latter is cleaved to produce glucosamine (GlcN) and N-acetylglucosamine (GlcNAc). The N-acetylglucosamine (GlcNAc) is then deacetylated to produce glucosamine (GlcN) and acetate.


name: aminoglycoside antibiotic catabolic process

description: The chemical reactions and pathways resulting in the breakdown of an aminoglycoside antibiotic, any member of a group of broad spectrum antibiotics, of similar toxicity and pharmacology, that contain an aminodeoxysugar, an amino- or guanidino-substituted inositol ring, and one or more residues of other sugars. The group includes streptomycin, neomycin, framycetin, kanamycin, paromomycin, and gentamicin.


name: ergosteryl 3-beta-D-glucoside catabolic process

description: The chemical reactions and pathways resulting in the breakdown of ergosteryl 3-beta-D-glucoside.


N-acetylmannosamine catabolic process

description: The chemical reactions and pathways resulting in the breakdown of N-acetylmannosamine, the acetylated derivative of mannosamine, 2-amino-2-deoxymannose.


mannosamine catabolic process

description: The chemical reactions and pathways resulting in the breakdown of mannosomine, 2-amino-2-deoxymannose; the D-isomer is a constituent of neuraminic acids as well as mucolipids and mucoproteins.


mannoprotein catabolic process

description: The chemical reactions and pathways resulting in the breakdown of a mannoprotein, a protein that contains covalently bound mannose residues.


thymidine catabolic process

description: The chemical reactions and pathways resulting in the breakdown of thymidine, deoxyribosylthymine thymine 2-deoxyriboside, a deoxynucleoside very widely distributed but occurring almost entirely as phosphoric esters in deoxynucleotides and deoxyribonucleic acid, DNA.


deoxyadenosine catabolic process

description: The chemical reactions and pathways resulting in the breakdown of deoxyadenosine, 2-deoxyribosyladenine, one of the four major nucleosides of DNA.


teichoic acid catabolic process

description: The chemical reactions and pathways resulting in the breakdown of teichoic acid, which is a major component of the cell wall of Gram-positive bacteria and typically consists of a polymer of glycerol-phosphate or ribitol-phosphate to which are attached glycosyl and D-alanyl ester residues.


cyanogenic glycoside catabolic process

description: The chemical reactions and pathways resulting in the breakdown of cyanogenic glycosides, any glycoside containing a cyano group that is released as hydrocyanic acid on acid hydrolysis; such compounds occur in the kernels of various fruits.


heparin catabolic process

description: The chemical reactions and pathways resulting in the breakdown of heparin, any member of a group of glycosaminoglycans of average Mr (6000-20000), consisting predominantly of alternating alpha-(1->4)-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues.


name: purine deoxyribonucleoside catabolic process

description: The chemical reactions and pathways resulting in the breakdown of any one of a family of organic molecules consisting of a purine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside).


deoxyguanosine catabolic process

description: The chemical reactions and pathways resulting in the breakdown of deoxyguanosine, a nucleoside consisting of the base guanine and the sugar deoxyribose.


lipooligosaccharide catabolic process

description: The chemical reactions and pathways resulting in the breakdown of lipooligosaccharide.


saponin catabolic process

description: The chemical reactions and pathways resulting in the breakdown of saponins, glycosides of plants in which the aglycan (sapogenin) group is a terpene or steroid and the sugar group is a glucose, a galactose, a pentose, a methylpentose or an oligosaccharide. Saponins are powerful surfactant agents and membrane active; they are, hence, toxic to animals on injection.


beta-glucoside catabolic process

description: The chemical reactions and pathways resulting in the breakdown of beta-glucoside.


uridine catabolic process

description: The chemical reactions and pathways resulting in the breakdown of uridine, uracil riboside, a ribonucleoside very widely distributed but occurring almost entirely as phosphoric esters in ribonucleotides and ribonucleic acids.


name: zeaxanthin bis(beta-D-glucoside) catabolic process

description: The chemical reactions and pathways resulting in the breakdown of zeaxanthin bis(beta-D-glucoside).


elastin catabolic process

description: The chemical reactions and pathways resulting in the breakdown of elastin. Elastin is a glycoprotein which is randomly coiled and crosslinked to form elastic fibers that are found in connective tissue.


pyridine nucleoside catabolic process

description: The chemical reactions and pathways resulting in the breakdown of any pyridine nucleoside, a nucleoside in which a pyridine base covalently bonded to a sugar, usually ribose.


queuosine catabolic process

description: The chemical reactions and pathways resulting in the breakdown of queuosines, any of a series of nucleosides found in tRNA and having an additional pentenyl ring added via an NH group to the methyl group of 7-methylguanosine. The pentenyl ring may carry other substituents.


fructosamine catabolic process

description: The chemical reactions and pathways resulting in the breakdown of fructosamine, a fructose molecule containing an amino group in place of a hydroxyl group.


name: Recurrent Childhood Gemistocytic Astrocytoma

description: The reemergence of gemistocytic astrocytoma in childhood after a period of remission.


Recurrent Astrocytic Tumor

description: The reemergence of an astrocytic tumor after a period of remission.


name: Recurrent Childhood Cerebellar Astrocytoma

description: Regrowth of benign and malignant childhood cerebellar astrocytomas that have previously been subjected to surgical resection and less frequently other forms of therapy such as radiation or chemotherapy.  Recurrence of benign tumors (e.g., (pilocytic astrocytoma) may respond to a second surgical procedure.


name: Recurrent Childhood Pleomorphic Xanthoastrocytoma

description: The reemergence of pleomorphic xanthoastrocytoma in childhood after a period of remission.


Recurrent MGMT-Methylated Glioblastoma

description: The reemergence of MGMT-methylated glioblastoma after a period of remission.


name: Recurrent Childhood Anaplastic Astrocytoma

description: The reemergence of anaplastic astrocytoma in childhood after a period of remission.


name: Recurrent Anaplastic Pleomorphic Xanthoastrocytoma

description: The reemergence of anaplastic pleomorphic xanthoastrocytoma after a period of remission.


name: Recurrent Childhood Visual Pathway Astrocytoma

description: The reemergence of visual pathway astrocytoma in childhood after a period of remission.


Recurrent Childhood Astrocytic Tumor

description: The reemergence of a childhood astrocytic tumor after a period of remission.


name: Recurrent Childhood Cerebral Astrocytoma

description: The reemergence of cerebral astrocytoma in childhood after a period of remission.


name: Recurrent Anaplastic Astrocytoma, IDH-Wildtype

description: The reemergence of anaplastic astrocytoma, IDH-wildtype after a period of remission.


Recurrent Childhood Diffuse Astrocytoma

description: The reemergence of diffuse astrocytoma in childhood after a period of remission.


Recurrent Gliosarcoma

description: The reemergence of gliosarcoma after a period of remission.


Recurrent Childhood Glioblastoma

description: The reemergence of glioblastoma in childhood after a period of remission.


Recurrent Glioblastoma, IDH-Wildtype

description: The reemergence of glioblastoma, IDH-wildtype after a period of remission.


Recurrent Giant Cell Glioblastoma

description: The reemergence of giant cell glioblastoma after a period of remission.


Recurrent Anaplastic Astrocytoma

description: The reemergence of anaplastic astrocytoma after a period of remission.


name: Recurrent Childhood Pilomyxoid Astrocytoma

description: The reemergence of pilomyxoid astrocytoma in childhood after a period of remission.


Recurrent Astrocytoma, IDH-Mutant

description: The reemergence of IDH-mutant astrocytoma after a period of remission.


Recurrent Childhood Gliosarcoma

description: The reemergence of gliosarcoma in childhood after a period of remission.


name: Recurrent Childhood Giant Cell Glioblastoma

description: The reemergence of giant cell glioblastoma in childhood after a period of remission.


name: Recurrent Astrocytoma, IDH-Mutant, Grade 4

description: The reemergence of astrocytoma, IDH-mutant, Grade 4, after a period of remission.


Recurrent Diffuse Astrocytoma

description: The reemergence of diffuse astrocytoma after a period of remission.


name: Recurrent Childhood Subependymal Giant Cell Astrocytoma

description: The reemergence of subependymal giant cell astrocytoma in childhood after a period of remission.


name: Recurrent Childhood Pilocytic Astrocytoma

description: The reemergence of pilocytic astrocytoma in childhood after a period of remission.


Recurrent Glioblastoma

description: The reemergence of glioblastoma after a period of remission.


name: Recurrent Childhood Optic Nerve Astrocytoma

description: The reemergence of optic nerve astrocytoma in childhood after a period of remission.


Recurrent Small Cell Glioblastoma

description: The reemergence of small cell glioblastoma after a period of remission.


Recurrent Supratentorial Glioblastoma

description: The reemergence of supratentorial glioblastoma after a period of remission.


name: Recurrent Childhood Fibrillary Astrocytoma

description: The reemergence of fibrillary astrocytoma in childhood after a period of remission.


name: Recurrent Astrocytoma, IDH-Mutant, Grade 3

description: The reemergence of astrocytoma, IDH-mutant, grade 3 after a period of remission.


Recurrent Brain Glioblastoma

description: The reemergence of brain glioblastoma after a period of remission.


Recurrent Pilocytic Astrocytoma

description: The reemergence of pilocytic astrocytoma after a period of remission.


Recurrent Low Grade Astrocytoma

description: The reemergence of a low grade astrocytoma after a period of remission.


name: Recurrent Childhood Brain Stem Astrocytoma

description: The reemergence of brain stem astrocytoma in childhood after a period of remission.


name: U12-type post-mRNA release spliceosomal complex

description: A spliceosomal complex that is formed following the release of the spliced product from the post-spliceosomal complex and contains the excised intron and the U12, U5 and U6atac snRNPs.


U12-type prespliceosome

description: A spliceosomal complex that is formed by the cooperative binding of the heterodimeric U11/U12 snRNP to the 5' splice site and the branch point sequence. The U12-type prespliceosome includes many proteins in addition to those found in the U11/U12 heterodimeric snRNPs. Commitment to a given pair of 5' and 3' splice sites occurs at the time of prespliceosome formation.


U12-type precatalytic spliceosome

description: A spliceosomal complex that is formed by the recruitment of the preassembled U4atac/U6atac.U5 tri-snRNP to the U12-type prespliceosome. Although all 5 snRNPs are present, the precatalytic spliceosome is catalytically inactive. The precatalytic spliceosome includes many proteins in addition to those found in the U11, U12 and U4atac/U6atac.U5 snRNPs.


U12-type post-spliceosomal complex

description: A spliceosomal complex that is formed following the second splicing event and contains the spliced product, the excised intron, and three snRNPs, U5, U12 and U6atac.


U2-type post-spliceosomal complex

description: A spliceosomal complex that is formed following the second splicing event and contains the spliced product, the excised intron, and three snRNPs, U5, U2 and U6.


U12-type catalytic step 2 spliceosome

description: A spliceosomal complex that contains the U12, U5 and U6atac snRNPs bound to a splicing intermediate in which the first catalytic cleavage of the 5' splice site has occurred. The precise subunit composition differs significantly from that of the catalytic step 1, or activated, spliceosome, and includes many proteins in addition to those found in the U12, U5 and U6atac snRNPs.


U2-type precatalytic spliceosome

description: A spliceosomal complex that is formed by the recruitment of the preassembled U4/U6.U5 tri-snRNP to the prespliceosome. Although all 5 snRNPs are present, the precatalytic spliceosome is catalytically inactive. The precatalytic spliceosome includes many proteins in addition to those found in the U1, U2 and U4/U6.U5 snRNPs.


trans spliceosomal complex

description: A spliceosomal complex that forms during the addition of a specific spliced leader (SL) sequence to the 5'-end of a messenger RNA primary transcript, a process which occurs in a number of eukaryotic organisms, including trypanosomatid protozoans, euglenoids, nematodes, trematodes, and chordates.


U12-type catalytic step 1 spliceosome

description: A spliceosomal complex that is formed by the displacement of the U11 and U4atac snRNPs from the precatalytic spliceosome; the U12, U5 and U6atac snRNPs remain associated with the mRNA. This complex, sometimes called the activated spliceosome, is the catalytically active form of the spliceosome, and includes many proteins in addition to those found in the U12, and U5 and U6atac snRNPs.


U2-type catalytic step 2 spliceosome

description: A spliceosomal complex that contains the U2, U5 and U6 snRNPs bound to a splicing intermediate in which the first catalytic cleavage of the 5' splice site has occurred. The precise subunit composition differs significantly from that of the catalytic step 1, or activated, spliceosome, and includes many proteins in addition to those found in the U2, U5 and U6 snRNPs.


description: A reactive cutaneous proliferation of macrophages. It is characterized by the presence of giant cells with ground-glass cytoplasm. It presents with multiple cutaneous or mucosal papules or nodules.


name: negative regulation of establishment of endothelial barrier

description: Any process that stops, prevents or reduces the frequency, rate or extent of establishment of endothelial barrier.


regulation of aplanospore formation

description: Any process that modulates the frequency, rate or extent of aplanospore formation, a process in which a nonmotile, asexual spore is formed within a cell in certain algae and fungi (commonly in the Phycomycetes), the wall of aplanospore is distinct from that of the parent cell.


name: positive regulation of aplanospore formation

description: Any process that activates, maintains or increases the frequency, rate or extent of aplanospore formation, a process in which a nonmotile, asexual spore is formed within a cell in certain algae and fungi (commonly in the Phycomycetes), the wall of aplanospore is distinct from that of the parent cell.


name: Epididymal Melanotic Neuroectodermal Tumor

description: A rare neoplasm that arises from the epididymis and is characterized by the presence of a mixture of melanin-containing epithelial cells and smaller neuroblast-like cells. It usually occurs in infants and has a benign clinical course.


organ system subdivision

description: A subdivision of an anatomical system.


name: insect embryonic/larval central nervous system

description: Central nervous system of the embryo/larva.


insect adult central nervous system

description: Central nervous system of the adult.


subdivision of skeletal system

description: Anatomical cluster consisting of the skeletal elements and articular elements that are part of an individual subdivision of the organism.


subdivision of skeleton

description: Anatomical cluster consisting of the skeletal elements (i.e. bone elements, cartilage elements, cartilage condensations) that are part of an individual subdivision of the organism. Excludes joints.


musculature

description: A subdivision of the muscular system corresponding to a subdisivision of an organism.


meckelian bone

description: The ossification of the Meckel's cartilage.


name: ATP-dependent H2AZ histone chaperone activity

description: A histone chaperone that mediates the exchange of histone H2A-H2B dimer and histone H2AZ-H2B dimers in a nucleosome, driven by ATP hydrolysis. Some chaperones insert H2AZ-H2B dimers and remove H2A-H2B, while others do the opposite.


maltose transporting porin activity

description: Enables the transfer of maltose from one side of a membrane to the other. Maltose is the disaccharide 4-O-alpha-D-glucopyranosyl-D-glucopyranose, an intermediate in the enzymatic breakdown of glycogen and starch. This transporter is a porin so enables the energy independent passage of substances, sized less than 1000 Da, across a membrane. The transmembrane portions of porins consist exclusively of beta-strands which form a beta-barrel. They are found in the outer membranes of Gram-negative bacteria, mitochondria, plastids and possibly acid-fast Gram-positive bacteria.


name: insulin-like growth factor binary complex

description: A complex of two proteins, which in animals is 50kDa and consists of the insulin-like growth factor (IGF) and one of the insulin-like growth factor binding protein-1 (IGFBP-1), -2 (IGFBP-2), -4 (IGFBP-4) and -6 (IGFBP-6). The complex plays a role in growth and development.


name: regulation of telomeric loop disassembly

description: Any process that modulates the frequency, rate or extent of telomeric loop disassembly.


name: positive regulation of telomeric D-loop disassembly

description: Any process that activates or increases the frequency, rate or extent of telomeric D-loop disassembly.


name: positive regulation of telomeric loop disassembly

description: Any process that activates or increases the frequency, rate or extent of telomeric loop disassembly.


name: regulation of telomeric D-loop disassembly

description: Any process that modulates the frequency, rate or extent of telomeric D-loop disassembly.


left anterior cardinal vein

description: An anterior cardinal vein that is in_the_left_side_of a multicellular organism.


cardinal vein

description: Any of the four veins in the developing vertebrate embryo which run along each side of the vertebral column.


left posterior cardinal vein

description: A posterior cardinal vein that is in_the_left_side_of a multicellular organism.


posterior cardinal vein

description: One of two paired cardinal veins that return blood from the body of the embryo[Kardong].


common cardinal vein

description: Either of a pair of large transverse venous sinuses that conduct blood from the cardinal veins to the sinus venosus of the vertebrate embryo[BTO].


right posterior cardinal vein

description: A posterior cardinal vein that is in_the_right_side_of a multicellular organism.


right anterior cardinal vein

description: An anterior cardinal vein that is in_the_right_side_of a multicellular organism.


anterior cardinal vein

description: One of the the two paired cardinal veins draining the cephalic part of the body.


facial nerve neoplasm

description: A neoplasm involving a facial nerve.


geniculate ganglionitis

description: Diseases of the facial nerve or nuclei. Pontine disorders may affect the facial nuclei or nerve fascicle. The nerve may be involved intracranially, along its course through the petrous portion of the temporal bone, or along its extracranial course. Clinical manifestations include facial muscle weakness, loss of taste from the anterior tongue, hyperacusis, and decreased lacrimation.


geniculate herpes zoster

description: A viral ear infection caused by the spread of varicella-zoster virus to the facial nerves. It is characterized by intense otalgia and a cutaneous vesicular eruption.


name: Moebius syndrome-axonal neuropathy-hypogonadotropic hypogonadism syndrome

description: This syndrome is characterized by the association of Moebius syndrome (congenital facial palsy with impaired ocular abduction) with peripheral axonal neuropathy and hypogonadotropic hypogonadism.


name: familial isolated deficiency of vitamin E

description: Ataxia with vitamin E deficiency (AVED) is a neurodegenerative disease belonging to the inherited cerebellar ataxias. It is mainly characterized by progressive spino-cerebellar ataxia, loss of proprioception, areflexia, and is associated with a marked deficiency in vitamin E.


hypertriglyceridemia 1

description: A laboratory test result indicating an autosomal dominant condition in which there is increased very low density lipoprotein production, which leads to increased triglyceride concentration.


name: positive regulation of pheromone response MAPK cascade

description: Any process that activates or increases the frequency, rate or extent of a pheromone response MAPK cascade.


positive regulation of ERK5 cascade

description: Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the ERK5 cascade.


name: positive regulation of cell wall integrity MAPK cascade

description: Any process that activates or increases the frequency, rate or extent of MAPK cascade involved in cell wall organization or biogenesis.


name: tRNA adenosine(64)-2'-O-ribosylphosphate transferase activity

description: Catalysis of the transfer of a phosphoribosyl group from 5'-phosphoribosyl-1'-pyrophosphate to position 64 of initiator tRNA.


female somatic sex determination

description: The determination of sex and sexual phenotypes in a female organism's soma.


NIK deficiency

description: A immunodeficiency disorder caused by loss of function mutation in NIK (MAP3K14).


name: plasma membrane proton-transporting V-type ATPase, V0 domain

description: The V0 domain of a proton-transporting V-type ATPase found in the plasma membrane.


name: lysosomal proton-transporting V-type ATPase, V0 domain

description: The V0 domain of a proton-transporting V-type ATPase found in the lysosomal membrane.


transient retinal arterial occlusion

description: A partial, temporary occlusion of the retinal artery.


arterial disorder

description: An impairment of the structure or function of the blood vessels which carry blood away from the heart.


Hepatic Arterial Occlusion

description: An occlusion of the hepatic artery.


Efferent Arteriolar Hyalinosis

description: The deposition of hyaline material in the wall of the efferent arterioles.


Vertebral Artery Dissection

description: A tear within the wall of a vertebral artery.


Dissection of renal artery

description: A tear within the wall of a renal artery.


Dissection, Thoracoabdominal Aorta

description: A tear within the wall of the thoracoabdominal aorta.


Dissection, Thoracic Aorta

description: A tear within the wall of the thoracic aorta.


Juvenile polyarteritis

description: Polyarteritis occurring in children or adolescents.


Systemic Arterial Hypertensive Disorder

description: Any condition resulting in systemically elevated blood pressure that is attributed to an arterial source.


coronary atherosclerosis

description: Atherosclerosis of the coronary vasculature.


Three Vessel Coronary Disease

description: There was greater than or equal to 50% stenosis (reduction in cross-sectional area) in three coronary arteries (or greater than or equal to 50% stenosis in the left main coronary artery and greater than or equal to 50% stenosis in the right coronary artery). (ACC)


Dissection of iliac artery

description: A tear within the wall of an iliac artery.


generalized atherosclerosis

description: Atherosclerosis that is not localized.


arterial occlusion

description: Complete closure of the normally patent lumen of the blood vessels which carry blood away from the heart.


partial arterial retinal occlusion

description: A partial occlusion of the retinal artery.


Infectious Arteritis

description: A bacterial or viral infectious process affecting an artery.


Overlap Necrotizing Arteritis

description: A necrotizing arteritis that exhibits characteristic features of several distinct vascular disorders.


vasculitis due to ADA2 deficiency

description: Vasculitis due to ADA2 deficiency is a rare, genetic, systemic and rheumatologic disease due to adenosine deaminase-2 inactivating mutations, combining variable features of autoinflammation, vasculitis, and a mild immunodeficiency. Variable clinical presentation includes chronic or recurrent systemic inflammation with fever, livedo reticularis or racemosa, early-onset ischemic or hemorrhagic strokes, peripheral neuropathy, abdominal pain, hepatosplenomegaly, portal hypertension, cutaneous polyarteritis nodosa, variable cytopenia and immunoglobulin deficiency.


microscopic polyangiitis

description: Microscopic polyangiitis (MPA) is an inflammatory, necrotizing, systemic vasculitis that affects predominantly small vessels (i.e. small arteries, arterioles, capillaries, venules) in multiple organs.


Double coronary vessel disease

description: There was greater than or equal to 50% stenosis (reduction in cross-sectional area) in two coronary arteries (or greater than or equal to 50% stenosis in the left main coronary artery). (ACC)


cerebral atherosclerosis

description: Atherosclerosis of the cerebral vasculature.


arteriolosclerosis

description: The thickening of the wall of the small arteries and arterioles. It is caused by deposition of hyaline material in the wall or concentric smooth muscle wall hypertrophy. It results in lumen narrowing and tissue ischemia.


Monckeberg arteriosclerosis

description: A type of arteriosclerosis in which calcification of the tunica media is the predominant feature.


One Vessel Coronary Disease

description: There was greater than or equal to 50% stenosis (reduction in cross-sectional area) in one coronary artery. (ACC)


cutaneous polyarteritis nodosa

description: Cutaneous polyarteritis nodosa (CPAN) is a rare limited form of polyarteritis nodosa (PAN), characterized by cutaneous vasculitis and mild and transient extracutaneous manifestations such as mild arthralgia, arthritis,myalgia, and rarely peripheral neuropathy.


Generalised arteriosclerosis

description: Arteriosclerosis that is not localized.


Significant Arterial Dissection

description: A dissection that impairs flow. This includes Type C (a persisting contrast medium extravasation) in the presence of ischemia, Type D (a spiral filling defect with delayed but complete distal flow), Type E (persistent filling defect with delayed antegrade flow) and Type F (filling defect with impaired flow and total occlusion).


Hyaline arteriolosclerosis

description: The deposition of hyaline material in the wall of the arterioles.


granulomatous angiitis

description: Inflammation of the arteries that is characterized by the presence of granulomas.


Femoropopliteal Occlusive Disease

description: An occlusive disease of the femoropopliteal vascular system.


endarteritis

description: Inflammation of the arterial intima.


name: chorionic trophoblast cell proliferation

description: The multiplication or reproduction of chorionic trophoblast cells, resulting in the expansion of their population.


Lung Radiation Injury

description: Radiation injury of the pulmonary system.


middle ear cholesterol granuloma

description: As accumulation of granulation tissue in the middle ear that results from the degeneration of blood and a chronic inflammatory response.


Cholesterol granuloma

description: A cystic inflammatory lesion that is comprised of fluids, lipids, and cholesterol crystals, and which is surrounded by a fibrous lining.


mycothiol biosynthetic process

description: The chemical reactions and pathways resulting in the formation of mycothiol, which consists of N-acetyl-L-cysteine linked to a pseudodisaccharide, D-glucosamine and myo-inositol. Mycothiol is produced in actinomycetes like mycobacteria and serves similar functions to glutathione.


Bronchospasm, Exercise-Induced

description: Sudden contraction of the smooth muscles of the bronchial wall that occurs during or following exercise.


name: Drug-induced cutaneous lupus erythematosus

description: A reaction to a drug characterized by skin findings common to lupus including photosensitivity and butterfly rash; typically it resolves after drug discontinuation.


lupus erythematosus tumidus

description: Tumid erythematosus lupus is considered a rare type of chronic cutaneous lupus erythematosus. Cutaneous lupus erythematosus (CLE) can be divided into acute cutaneous lupus, subacute cutaneous lupus, and chronic cutaneous lupus. Tumid erythematosus lupus is characterized by smooth, non-scarring, pink- to violet-colored pimples (papules)on the skin without any other apparent skin changes, such as scarring. Patients with tumid lupus erythematosus usually do not have other symptoms of systemic lupus erythematosus or other types of cutaneous lupus erythematosus. The papules appear on sun-exposed areas of the face, upper back, V area of the neck, trunk, and arms, and more rarely on thighs and legs. They usually affect equally both sides of the body, but may affect only one side. Normally, the papules clear without leaving scars. The treatment is very effective in most cases, and may include sun protection, anti-malarials drugs, local corticosteroids, topical tacrolimus and light therapy.


subacute cutaneous lupus erythematosus

description: Subacute cutaneous lupus erythematosus (SCLE) is a form of cutaneous lupus erythematosus (CLE) that can present either as a non-scarring, annular photo-distributed dermatosis or psoriasiform plaques. SCLE is associated with anti-Ro/SSA antibodies and can be drug-induced.


deoxyuridine biosynthetic process

description: The chemical reactions and pathways resulting in the formation of deoxyuridine, 2-deoxyribosyluracil, one of the four major nucleosides of DNA.


name: 1,1,2-trichloroethene reductive dehalogenase activity

description: Catalysis of the reaction: trichloroethene + 2 H+ + 2 e- = HCl + 1,2-dichloroethene.


description: Catalysis of the reaction: L-proline + NAD(P)+ = 1-pyrroline-2-carboxylate + NAD(P)H + H+.


skin of manus

description: A zone of skin that is part of a manus [Automatically generated definition].


manual digit skin

description: A zone of skin that is part of a finger [Automatically generated definition].


skin of wrist

description: A zone of skin that is part of a wrist [Automatically generated definition].


name: cellular response to external biotic stimulus

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external biotic stimulus, an external stimulus caused by, or produced by living things.


clear cell sarcoma

description: A rare malignant neoplasm with melanocytic differentiation characterized by the presence of polygonal or spindle shaped clear cells. This sarcoma usually affects the tendons and aponeuroses and is associated with a poor prognosis due to recurrences and metastases.


name: Childhood Clear Cell Sarcoma of Soft Parts

description: A clear cell sarcoma of soft tissue occurring in children.


name: Metastatic Clear Cell Sarcoma of Soft Tissue

description: A clear cell sarcoma of soft tissue that has spread from the original site of growth to other anatomic sites.


name: Advanced Clear Cell Sarcoma of Soft Tissue

description: A clear cell sarcoma of soft tissue that has spread extensively to other anatomic sites or is no longer responding to treatment.


name: Recurrent Clear Cell Sarcoma of Soft Tissue

description: The reemergence of clear cell sarcoma of soft tissue after a period of remission.


name: Refractory Clear Cell Sarcoma of Soft Tissue

description: Clear cell sarcoma of soft tissue that is resistant to treatment.


anatomical group

description: Anatomical structure consisting of at least two non-overlapping organs, multi-tissue aggregates or portion of tissues or cells of different types that does not constitute an organism, organ, multi-tissue aggregate, or portion of tissue.


name: COG4-congenital disorder of glycosylation

description: COG4-CDG is an extremely rare form of CDG syndrome characterized clinically in the single reported case to date by seizures, some dysmorphic features, axial hyponia, slight peripheral hypertonia and hyperreflexia.