triglyceride acyl-chain remodeling

description: Remodeling the acyl chains of triacylglycerol, through sequential deacylation and re-acylation reactions, to generate triacylglycerol containing different types of fatty acid acyl chains.


category: biolink:MolecularActivity biolink:Occurrent biolink:OntologyClass biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: Catalysis of the reaction: L-phenylalanine + 2 NADPH + 2 O2 + 2 H+ = (E)-phenylacetaldehyde oxime + 2 NADP + 3 H2O + carbon dioxide.


name: Hodgkin's disease mixed cellularity stage II subdiaphragmatic

category: biolink:Disease biolink:DiseaseOrPhenotypicFeature biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing


name: Ann Arbor Stage II Mixed Cellularity Classic Hodgkin Lymphoma

description: Ann Arbor Classification: Stage II: Involvement of two or more lymph node regions on the same side of the diaphragm (II); or localized involvement of a single extralymphatic organ or site in association with regional lymph node involvement with or without involvement of other lymph node regions on the same side of the diaphragm (IIE).


name: Hodgkin's disease mixed cellularity stage II supradiaphragmatic


name: RNA exonuclease activity, producing 3'-phosphomonoesters

description: Catalysis of the hydrolysis of ester linkages within ribonucleic acids by removing nucleotide residues from the 3' or 5' end to yield 3' phosphomonoesters.


name: exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters

description: Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 3' or 5' end to yield 3' phosphomonoesters.


exodeoxyribonuclease VII activity

description: Catalysis of the exonucleolytic cleavage in either 5' to 3' or 3' to 5' direction to yield 5'-phosphomononucleotides.


name: DNA 5'-adenosine monophosphate hydrolase activity

description: Catalysis of the reaction: 5'-AMP-DNA + H2O = AMP + DNA; nucleophilic release of a covalently linked adenylate residue from a DNA strand, leaving a 5' phosphate terminus.


exoribonuclease II activity

description: Catalysis of the reaction: RNA + H2O = 5'-phosphomononucleotides. Cleaves RNA in the 3' to 5' direction.


exoribonuclease H activity

description: Catalysis of the exonucleolytic cleavage of RNA to 5'-phosphomonoester oligonucleotides in both 5' to 3' and 3' to 5' directions.


ribonuclease D activity

description: Catalysis of the exonucleolytic cleavage that removes extra residues from the 3'-terminus of tRNA to produce 5'-mononucleotides.


name: poly(U)-specific exoribonuclease activity, producing 3' uridine cyclic phosphate ends

description: Catalysis of 3' exonucleolytic cleavage of poly(U), to form poly(U)-N containing a 3' uridine cyclic phosphate (U>P).


5'-3' RNA exonuclease activity

description: Catalysis of the sequential cleavage of mononucleotides from a free 5' terminus of an RNA molecule.


exodeoxyribonuclease V activity

description: Catalysis of the exonucleolytic cleavage (in the presence of ATP) in either 5' to 3' or 3' to 5' direction to yield 5'-phosphooligonucleotides.


name: 3'-5'-exoribonuclease activity involved in mature miRNA 3'-end processing

description: Catalysis of the sequential cleavage of mononucleotides from a free 3' terminus of an RNA molecule that contributes to forming distinct miRNA isoforms from a mature miRNA.


name: double-stranded DNA 5'-3' DNA exonuclease activity

description: Catalysis of the sequential cleavage of mononucleotides from a free 5' terminus of a double-stranded DNA molecule.


D-tyrosine catabolic process

category: biolink:BiologicalProcess biolink:Occurrent biolink:OntologyClass biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: The chemical reactions and pathways resulting in the breakdown of D-tyrosine.


D-tyrosine metabolic process

description: The chemical reactions and pathways involving D-tyrosine.


name: promoter-enhancer loop anchoring activity

description: Bridging together two cis-regulatory elements, colloquially referred to as promoters and/or enhancers, holding two loop anchors together to maintain a chromatin loop.


Childhood Sympathetic Paraganglioma

description: A sympathetic paraganglioma that occurs during childhood.


Childhood Paraganglioma

description: A paraganglioma that occurs during childhood.


Childhood Parasympathetic Paraganglioma

description: A parasympathetic paraganglioma that occurs during childhood.


Childhood Composite Paraganglioma

description: A composite paraganglioma that occurs during childhood.


name: epithelial cell migration, open tracheal system

description: The orderly movement of epithelial cells during development of an open tracheal system. An example of this is found in Drosophila melanogaster.


DELTA-TOCOTRIENOL

A tocotrienol that is chroman-6-ol substituted by methyl groups at positions 2 and 8 and a farnesyl chain at position 2.


chromanol

Any member of the class of chromanes that is chromane substituted by one or more hydroxy groups.


(S,R,S)-alpha-tocopherol

The (S,R,S)-stereoisomer of alpha-tocopherol.


beta-tocotrienol

A tocotrienol that is chroman-6-ol substituted by methyl groups at positions 2, 5 and 8 and a farnesyl chain at position 2. It has been isolated from various cultivars of wheat.


(R,R,S)-alpha-tocopherol

The (R,R,S)-stereoisomer of alpha-tocopherol.


GAMMA-TOCOPHEROL

A tocopherol in which the chroman-6-ol core is substituted by methyl groups at positions 7 and 8. It is found particularly in maize (corn) oil and soya bean (soybean) oils.


A tocopherol in which the chroman-6-ol core is substituted by a methyl group at position 8. It is found particularly in maize (corn) oil and soya bean (soybean) oils.


(S,S,R)-alpha-tocopherol

The (S,S,R)-stereoisomer of alpha-tocopherol.


(R,S,R)-alpha-tocopherol

The (R,S,R)-stereoisomer of alpha-tocopherol.


tocol

A chromanol with a chroman-6-ol skeleton that is substituted at position 2 by a saturated or triply-unsaturated hydrocarbon chain consisting of three isoprenoid units.


tocopherol

A collective name for a group of closely related lipids that contain a chroman-6-ol nucleus substituted at position 2 by a methyl group and by a saturated hydrocarbon chain consisting of three isoprenoid units. They are designated as alpha-, beta-, gamma-, and delta-tocopherol depending on the number and position of additional methyl substituents on the aromatic ring. Tocopherols occur in vegetable oils and vegetable oil products, almost exclusively with R,R,R configuration. Tocotrienols differ from tocopherols only in having three double bonds in the hydrocarbon chain.


ALPHA-TOCOTRIENOL

A tocotrienol that is chroman-6-ol substituted by methyl groups at positions 2, 5, 7 and 8 and a farnesyl chain at position 2. It has been found in palm oil derived from Elaeis guineensis.


beta-tocopherol

A tocopherol in which the chroman-6-ol core is substituted by methyl groups at positions 5 and 8. While it is found in low concentrations in many vegetable oils, only cottonseed oil contains significant amounts.


(S,S,S)-alpha-tocopherol

The (S,S,S)-stereoisomer of alpha-tocopherol.


(S,R,R)-alpha-tocopherol

The (S,R,R)-stereoisomer of alpha-tocopherol.


alpha-tocopherol

A tocopherol that is chroman-6-ol substituted by methyl groups at positions 2, 5, 7 and 8 and a 4,8,12-trimethyltridecyl group at position 2.


(R,S,S)-alpha-tocopherol

The (R,S,S)-stereoisomer of alpha-tocopherol.


GAMMA-TOCOTRIENOL

A tocotrienol that is chroman-6-ol substituted by methyl groups at positions 2, 7 and 8 and a farnesyl chain at position 2. A vitamin E family member that has potent anti-cancer properties against a wide-range of cancers.


sinoatrial valve morphogenesis

description: The process in which the structure of the sinoatrial valve is generated and organized.


name: Mismatch Repair-Deficient Endometrial Endometrioid Adenocarcinoma

description: An endometrial endometrioid adenocarcinoma characterized by mismatch repair (MMR) deficiency caused by inactivating methylation or less frequently mutation of an MMR gene (MLH1, PMS2, MSH2, or MSH6).


name: 1-18:1-2-18:2-phosphatidylcholine desaturase activity (SN2-18:3 forming)

description: Catalysis of the reaction: 1-18:1-2-18:2-phosphatidylcholine + O2 + a reduced electron acceptor = 1-18:1-2-18:3-phosphatidylcholine + 2 H2O + an oxidized electron acceptor.


Uterine Corpus Neuroendocrine Tumor G1

description: A very rare, well-differentiated, low-grade neuroendocrine neoplasm that arises from the uterine corpus.


Stress ulcer

description: An ulcer due to stress.


Orbit Solitary Fibrous Tumor

description: A solitary fibrous tumor that arises from the orbit. Most of these tumors are benign.


name: cytoplasmic side of late endosome membrane

category: biolink:CellularComponent biolink:AnatomicalEntity biolink:PhysicalEssence biolink:OrganismalEntity biolink:SubjectOfInvestigation biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: The side (leaflet) of the late endosome membrane that faces the cytoplasm.


name: tetracenomycin B3 8-O-methyl transferase activity

description: Catalysis of the reaction: tetracenomycin B3 + S-adenosyl-L-methionine = tetracenomycin E + S-adenosyl-L-homocysteine + H+.


abdominal ganglion

category: biolink:AnatomicalEntity biolink:PhysicalEssence biolink:OrganismalEntity biolink:SubjectOfInvestigation biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: A ganglion that is part of a abdominal segment of trunk.


plasma membrane

description: The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.


name: apical plasma membrane urothelial plaque

description: A scallop-shaped plaque, also referred to as an asymmetric unit membrane (AUM), found in the apical plasma membrane of urothelial superficial (umbrella) cells which form a a barrier to the passage of water and soluble toxic compounds found in urine. The plaques are thickened regions of membrane composed of uroplakin transmembrane proteins which form a crystalline array.


name: positive regulation of molecular function

description: Any process that activates or increases the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding.


name: positive regulation of exonuclease activity

description: Any process that activates or increases the frequency, rate or extent of exonuclease activity.


positive regulation of RNA binding

description: Any process that activates or increases the frequency, rate or extent of RNA binding.


name: positive regulation of glucosylceramidase activity

description: Any process that activates or increases the frequency, rate or extent of glucosylceramidase activity.


positive regulation of collagen binding

description: Any process that activates or increases the frequency, rate or extent of collagen binding.


name: positive regulation of D-amino-acid oxidase activity

description: Any process that activates or increases the frequency, rate or extent of D-amino-acid oxidase activity.


name: positive regulation of arginase activity

description: Any process that activates or increases the frequency, rate or extent of arginase activity.


name: positive regulation of iron ion transmembrane transporter activity

description: Any process that activates or increases the frequency, rate or extent of an iron transmembrane transporter activity.


name: positive regulation of inward rectifier potassium channel activity

description: Any process that activates or increases the frequency, rate or extent of inward rectifier potassium channel activity.


name: positive regulation of advanced glycation end-product receptor activity

description: Any process that activates or increases the frequency, rate or extent of advanced glycation end-product receptor activity.


name: positive regulation of glucagon-like peptide receptor 1 activity in another organism

description: A process that activates or increases the frequency, rate or extent of the activity of a glucagon-like peptide receptor 1 in a second organism.


name: negative regulation of guanyl-nucleotide exchange factor activity

description: Any process that stops, prevents or reduces the frequency, rate or extent of guanyl-nucleotide exchange factor activity.


name: positive regulation of potassium:proton exchanging ATPase activity

description: Any process that activates or increases the frequency, rate or extent of hydrogen:potassium-exchanging ATPase activity.


name: positive regulation of pyruvate dehydrogenase activity

description: Any process that activates or increases the frequency, rate or extent of pyruvate dehydrogenase activity.


name: positive regulation of phosphodiesterase I activity

description: Any process that activates or increases the frequency, rate or extent of phosphodiesterase I activity.


name: positive regulation of glutamate-cysteine ligase activity

description: Any process that activates or increases the activity of glutamate-cysteine ligase, typically by lowering its sensitivity to inhibition by glutathione and by increasing its affinity for glutamate.


name: positive regulation of creatine transmembrane transporter activity

description: Any process that activates or increases the frequency, rate or extent of creatine transmembrane transporter activity.


name: positive regulation of RNA-dependent RNA polymerase activity

description: Any process that activates or increases the frequency, rate or extent of RNA-directed 5'-3' RNA polymerase activity.


name: positive regulation of pyruvate kinase activity

description: Any process that activates or increases the frequency, rate or extent of pyruvate kinase activity.


name: positive regulation of recombination hotspot binding

description: Any process that activates or increases the frequency, rate or extent of recombination hotspot binding.


name: positive regulation of nerve growth factor receptor activity

description: Any process that activates or increases the frequency, rate or extent of the activity of the nerve growth factor (NGF) receptor.


name: positive regulation of peroxidase activity

description: Any process that activates or increases the frequency, rate or extent of peroxidase activity.


positive regulation of mRNA cap binding

description: Any process that activates or increases the frequency, rate or extent of mRNA cap binding.


name: positive regulation of prostaglandin-E synthase activity

description: Any process that activates or increases the frequency, rate or extent of prostaglandin-E synthase activity.


name: positive regulation of choline O-acetyltransferase activity

description: Any process that activates or increases the frequency, rate or extent of choline O-acetyltransferase activity.


name: positive regulation of ATP citrate synthase activity

description: Any process that activates or increases the frequency, rate or extent of ATP citrate synthase activity.


name: positive regulation of water channel activity

description: Any process that activates or increases the frequency, rate or extent of water channel activity.


name: positive regulation of mRNA 3'-UTR binding

description: Any process that activates or increases the frequency, rate or extent of mRNA 3'-UTR binding.


name: positive regulation of malate dehydrogenase (decarboxylating) (NADP+) activity

description: Any process that activates or increases the frequency, rate or extent of malate dehydrogenase (decarboxylating) (NADP+) activity.


name: positive regulation of double-stranded telomeric DNA binding

description: Any process that activates or increases the frequency, rate or extent of double-stranded telomeric DNA binding.


positive regulation of mRNA binding

description: Any process that activates or increases the frequency, rate or extent of mRNA binding.


name: positive regulation of alpha-(1->3)-fucosyltransferase activity

description: Any process that activates or increases the frequency, rate or extent of alpha-(1->3)-fucosyltransferase activity.


name: positive regulation of beta-galactosidase activity

description: Any process that activates or increases the frequency, rate or extent of beta-galactosidase activity.


name: positive regulation of selenocysteine insertion sequence binding

description: Any process that activates or increases the frequency, rate or extent of selenocysteine insertion sequence binding.


name: positive regulation of voltage-gated sodium channel activity in another organism

description: Any process that activates or increases the frequency, rate or extent of the activity of a voltage-gated sodium channel in another organism.


name: positive regulation of catalase activity

description: Any process that activates or increases the frequency, rate or extent of catalase activity.


name: positive regulation of cyclic nucleotide-gated ion channel activity

description: Any process that activates or increases the frequency, rate or extent of cyclic nucleotide-gated ion channel activity.


name: positive regulation of molecular function in another organism

description: Any process that activates or increases the frequency, rate or extent of the function of proteins in a second organism.


name: positive regulation of G protein-coupled receptor activity in another organism

description: A process that activates or increases the frequency, rate or extent of the activity of a G protein-coupled receptor in a second organism.


name: positive regulation of glutathione peroxidase activity

description: Any process that activates or increases the frequency, rate or extent of glutathione peroxidase activity.


name: positive regulation of endoribonuclease activity

description: Any process that activates or increases the frequency, rate or extent of endoribonuclease activity.


name: positive regulation of DNA replication origin binding

description: Any process that activates or increases the frequency, rate or extent of DNA replication origin binding.


name: positive regulation of guanyl-nucleotide exchange factor activity

description: Any process that activates or increases the frequency, rate or extent of guanyl-nucleotide exchange factor activity.


name: positive regulation of single-stranded telomeric DNA binding

description: Any process that increases the frequency, rate or extent of single-stranded telomeric DNA binding.


name: positive regulation of methylenetetrahydrofolate reductase (NAD(P)H) activity

description: Any process that activates or increases the frequency, rate or extent of methylenetetrahydrofolate reductase (NAD(P)H) activity.


positive regulation of urease activity

description: Any process that activates or increases the frequency, rate or extent of urease activity.


name: positive regulation of glycogen synthase activity, transferring glucose-1-phosphate

description: Any process that activates or increases the frequency, rate or extent of glycogen synthase activity, transferring glucose-1-phosphate.


name: positive regulation of GTP cyclohydrolase I activity

description: Any process that activates or increases the activity of the enzyme GTP cyclohydrolase I.


name: positive regulation of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands

description: Any process that activates or increases the frequency, rate or extent of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands.


name: positive regulation of water channel activity involved in maintenance of lens transparency

description: Any positive regulation of water channel activity that is involved in maintenance of lens transparency.


name: positive regulation of osmolarity-sensing cation channel activity

description: Any process that activates or increases the frequency, rate or extent of osmolarity-sensing cation channel activity.


name: positive regulation of corticotropin-releasing hormone receptor activity

description: Any process that activates or increases the frequency, rate or extent of corticotropin-releasing hormone receptor activity.


name: positive regulation of GABA-A receptor activity

description: Any process that activates or increases the frequency, rate or extent of GABA-A receptor activity.


name: positive regulation of threonine-tRNA ligase activity

description: Any process that activates or increases the frequency, rate or extent of threonine-tRNA ligase activity.


name: positive regulation of lipid transporter activity

description: Any process that increases the frequency, rate, or extent of lipid transporter activity.


name: positive regulation of proton-transporting ATP synthase activity, rotational mechanism

description: Any process that activates or increases the frequency, rate or extent of proton-transporting ATP synthase activity, rotational mechanism.


name: positive regulation of isoleucine-tRNA ligase activity

description: Any process that activates or increases the frequency, rate or extent of isoleucine-tRNA ligase activity.


name: positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding

description: Any process that activates or increases the frequency, rate or extent of RNA polymerase II regulatory region sequence-specific DNA binding.


name: positive regulation of protein-glutamine gamma-glutamyltransferase activity

description: Any process that activates or increases the frequency, rate or extent of protein-glutamine gamma-glutamyltransferase activity.


name: positive regulation of heme oxygenase activity

description: Any process that activates or increases the frequency or rate of heme oxygenase activity.


name: positive regulation of CoA-transferase activity

description: Any process that activates or increases the frequency, rate or extent of CoA-transferase activity.


name: positive regulation of G-quadruplex DNA binding

description: Any process that activates or increases the frequency, rate or extent of G-quadruplex DNA binding.


name: positive regulation of lysozyme activity

description: Any process that activates or increases the frequency, rate or extent of lysozyme activity.


name: positive regulation of vasoactive intestinal polypeptide receptor activity in another organism

description: A process that activates or increases the frequency, rate or extent of the activity of a vasoactive intestinal polypeptide receptor in a second organism.


name: positive regulation of tyrosinase activity

description: Any process that activates or increases the activity of a tyrosinase enzyme monophenol oxygenase.


name: positive regulation of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity

description: Any process that activates or increases the frequency or rate of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity.


name: positive regulation of triplex DNA binding

description: Any process that activates or increases the frequency, rate or extent of triplex DNA binding.


name: positive regulation of L-dopa decarboxylase activity

description: Any process that activates or increases the frequency, rate or extent of L-dopa decarboxylase activity.


name: positive regulation of oxidative phosphorylation uncoupler activity

description: Any process that activates or increases the frequency, rate or extent of oxidative phosphorylation uncoupler activity.


name: positive regulation of tyrosine 3-monooxygenase activity

description: Any process that activates or increases the frequency, rate or extent of tyrosine 3-monooxygenase activity.


name: positive regulation of exoribonuclease activity

description: Any process that activates or increases the frequency, rate or extent of exoribonuclease activity.


name: positive regulation of Rho guanyl-nucleotide exchange factor activity

description: Any process that activates or increases the frequency, rate or extent of Rho guanyl-nucleotide exchange factor activity.


name: positive regulation of polynucleotide adenylyltransferase activity

description: Any process that activates or increases the frequency, rate or extent of polynucleotide adenylyltransferase activity.


name: positive regulation of catalytic activity

description: Any process that activates or increases the activity of an enzyme.


name: positive regulation of NMDA glutamate receptor activity

description: Any process that activates or increases the frequency, rate or extent of NMDA glutamate receptor activity.


name: positive regulation of phospholipase D activity

description: Any process that activates or increases the frequency, rate or extent of phospholipase D activity.


name: positive regulation of poly(A)-specific ribonuclease activity

description: Any process that activates or increases the frequency, rate or extent of poly(A)-specific ribonuclease activity.


name: positive regulation of ribonucleoside-diphosphate reductase activity

description: Any process that activates or increases the frequency, rate or extent of ribonucleoside-diphosphate reductase activity.


name: positive regulation of methionine-tRNA ligase activity

description: Any process that activates or increases the frequency, rate or extent of methionine-tRNA ligase activity.


name: positive regulation of receptor activity in another organism

description: A process that activates or increases the frequency, rate or extent of the activity of a receptor in a second organism.


name: positive regulation of light-activated channel activity

description: Any process that activates or increases the frequency, rate or extent of light-activated channel activity.


name: positive regulation of heparan sulfate binding

description: Any process that activates or increases the frequency, rate or extent of heparan sulfate binding.


positive regulation of lipid binding

description: Any process that activates or increases the frequency, rate or extent of lipid binding.


name: positive regulation of proteinase activated receptor activity

description: Any process that activates or increases the frequency, rate or extent of proteinase activated receptor activity.


name: positive regulation of calcium ion binding

description: Any process that activates or increases the frequency, rate or extent of calcium ion binding.


name: positive regulation of DNA ligase activity

description: Any process that activates or increases the frequency, rate or extent of DNA ligase activity.


name: positive regulation of G-protein activated inward rectifier potassium channel activity

description: Any process that activates or increases the frequency, rate or extent of G-protein activated inward rectifier potassium channel activity.


name: positive regulation of euchromatin binding

description: Any process that activates or increases the frequency, rate or extent of euchromatin binding.


name: positive regulation of cystathionine beta-synthase activity

description: Any process that activates or increases the frequency, rate or extent of cystathionine beta-synthase activity.


name: positive regulation of pyrroline-5-carboxylate reductase activity

description: Any process that activates or increases the frequency, rate or extent of pyrroline-5-carboxylate reductase activity.


name: positive regulation of calcium-dependent ATPase activity

description: Any process that activates or increases the frequency, rate or extent of calcium-dependent ATPase activity.


name: negative regulation of Rho guanyl-nucleotide exchange factor activity

description: Any process that stops, prevents or reduces the frequency, rate or extent of Rho guanyl-nucleotide exchange factor activity.


name: positive regulation of dUTP diphosphatase activity

description: Any process that activates or increases the frequency, rate or extent of dUTP diphosphatase activity.


pinhole eye

category: biolink:GrossAnatomicalStructure biolink:AnatomicalEntity biolink:PhysicalEssence biolink:OrganismalEntity biolink:SubjectOfInvestigation biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: Simple eye that has a small aperture (which may be adjustable) and deep pit. It is only found in the nautiloids.


simple eye

description: An eye with one concave chamber. Note that 'simple' does not imply a reduced level of complexity or acuity.


camera-type eye

description: An organ of sight that includes the camera-type eyeball and supporting structures such as the lacrimal apparatus, the conjunctiva, the eyelid.


spherical lensed eye

description: Simple eye that consists of a lens of one refractive index.


simple eye with multiple lenses

description: Simple eye that has two or more lenses. Some marine organisms bear more than one lens; for instance the copeopod Pontella has three. The outer has a parabolic surface, countering the effects of spherical aberration while allowing a sharp image to be formed. Copilla's eyes have two lenses, which move in and out like a telescope.


stemma

description: Eye-spots which may be set into a pit to reduce the angles of light that enters and affects the eyespot, to allow the organism to deduce the angle of incoming light.


stroma

description: Connective, non-functional supportive framework of a biological cell, tissue, or organ. Contrast with parenchyma.


Connective and Soft Tissue

description: The supporting connective tissue of an organ.


endoneurium

description: The loose connective tissue within the perineurium that continues into nerve fascicles and surrounds individual fibers. (Nolte, J. The Human Brain 3rd edition).


eyelid connective tissue

description: A portion of connective tissue that is part of a eyelid [Automatically generated definition].


Volkmann's canal

description: Microscopic channels in the compact bone that run perpendicular to the Haversian canals.  They carry blood vessels from the periosteum into the bone and connect the Haversian canals with each other and the periosteum.


aorta endothelium

description: The thin layer of flat cells that line the aorta and form a barrier between circulating blood in the lumen and the rest of the vessel wall.


lymphatic vessel endothelium

description: An endothelium that is part of a lymphatic vessel [Automatically generated definition].


soft tissue

description: A general term comprising tissue that is not hardened or calcified; including muscle, fat, blood vessels, nerves, tendons, ligaments and fascia.


osteon

description: A circular structural unit of bone tissue. It consists of a central hole, the Haversian canal through which blood vessels run, surrounded by concentric rings, called lamellae.


compact bone tissue

description: The outer layers of solid, hard bone that covers spongy bone; consists of parallel osteons containing mineral deposits and interstitial lamellae.


arterial system endothelium

description: An endothelium that is part of an arterial system [Automatically generated definition].


endothelium of venule

description: An endothelium that is part of a venule [Automatically generated definition].


Blood Vessel Tissue

description: The tissue component of a blood vessel. Large vessels contain three layers of tissue, the tunica intima, tunica media, and tunica adventitia. Capillary tissue is composed of a single layer of endothelium and connective tissue.


endothelium of capillary

description: An endothelium that is part of a capillary [Automatically generated definition].


Visceral Striated Muscle Tissue

description: Muscle tissue associated with organs such as tongue, pharynx, diaphragm and upper part of the esophagus. It is identical in structure to skeletal muscle tissue.


fibrocartilage

description: Cartilage tissue intermediate between hyaline cartilage and dense connective tissue; contains of abundant collagen fibers; chondrocytes often arranged in columns.


larynx connective tissue

description: A portion of connective tissue that is part of a larynx [Automatically generated definition].


intestine smooth muscle

description: A portion of smooth muscle tissue that is part of a intestine [Automatically generated definition].


haversian canal

description: Haversian canals are a series of tubes around narrow channels formed by lamellae. This is the region of bone called compact bone. Osteons are arranged in parallel to the long axis of the bone. The Haversian canals surround blood vessels and nerve cells throughout the bone and communicate with osteocytes in lacunae (spaces within the dense bone matrix that contain the living bone cells) through canaliculi. This unique arrangement is conducive to mineral salt deposits and storage which gives bone tissue its strength.


blood vessel endothelium

description: An endothelium that lines the blood vasculature. Other endothelia may line lymph vessels, the heart.


gallbladder smooth muscle

description: A portion of smooth muscle tissue that is part of a gallbladder [Automatically generated definition].


aorta smooth muscle tissue

description: The nonstriated, involuntary muscle tissue located in the wall of the aorta.


Superficial Myometrium

description: The portion of myometrium adjacent to the endometrium.


perineurium

description: A layer of thin, concentrically arranged cells with interspersed collagen that lies within the epineurium. The perineurium is a component of the blood–nerve barrier and is essential for protecting axons and their associated Schwann cells from ionic flux, toxins and infection.


endothelium of artery

description: An endothelium that is part of an artery [Automatically generated definition].


dental pulp

description: The part in the center of a tooth made up of living soft tissue and cells called odontoblasts[WP].


glomerular capillary endothelium

description: An endothelium that is part of a glomerular capillary.


muscle tissue of prostate

description: A muscle tissue that is part of a prostate gland.


eyelid subcutaneous connective tissue

description: An eyelid connective tissue that is part of a hypodermis.


blood vessel smooth muscle

description: Smooth muscle found within, and composing the majority of the wall of blood vessels.


Lamellar bone

description: A type of bone tissue. There are two subtypes of mature bone - compact and spongy. Compact bone is very dense and hard on the outside. Compact bone forms the thick-walled tube of the shaft of long bones and covers the epiphyses of long bones. Spongy bone is lightweight and consists of trabeculae, which branch and intersect to form a sponge like network, and red bone marrow for hematopoiesis. Short bones and the epiphyses of long bones consist mainly of spongy bone.


name: Connective Tissue Component of the Peripheral Nerve


cementum

description: Odontoid tissue that is deposited by cementoblasts onto dentine tissue and functions to attach teeth, odontodes and other odontogenic derivatives to bone tissue and the integument.


endothelium of arteriole

description: An endothelium that is part of an arteriole [Automatically generated definition].


Medullary Bone

description: The central and spongy portion of the bone.


Demineralized Bone Tissue

description: Bone that has had most of the mineralized components removed while retaining collagen and noncollagenous proteins.


Structure of iliotibial tract

description: A dense band of avascular, regular connective tissue, it is formed as the union of the superficial and deep layers of the tensor fascia latae, creating a thick band that extends inferiorly, taking its origins from the iliac crest, the tensor fascia latae, and the gluteus maximus, travelling inferiolaterally along the thigh, and inserting on Gerdy's tubercle on the lateral aspect of the tibia. Functionally, the iliotibial band helps to flex, abduct, and medially rotate the femur at the hip joint, and it also helps to stabilize the knee laterally.


epineurium

description: A loose connective tissue sheath surrounding each peripheral nerve. Composed mainly of colagen and fibroblasts, it forms a substantial covering over nerve trunks, then thins to an incomplete layer around smaller branches near their terminations. The epineurium is continuous centrally with the dura. Peripherally, it usually ends near the termination of a nerve fiber, but it may continue as the capsule of Meissner corpuscles and a few other encapsulated endings. Nolte, J. The Human Brain 3rd edition.


hyaline cartilage tissue

description: Cartilage tissue primarily composed of type II collagen (thin fibrils) and a glassy appearance.


Immature Bone

description: The earliest tissue to appear in embryonic development (it is the predominant bone in the developing fetus) and post fracture. The collagenous lamellae are randomly oriented and loosely intertwined. It is characterized by coarse fiber bundles approximately 30 um in diameter.


venous system endothelium

description: An endothelium that is part of a venous system [Automatically generated definition].


striated muscle tissue

description: Muscle tissue that contains fibers that are divided by transverse bands into striations.


endothelium of vein

description: An endothelium that is part of a vein [Automatically generated definition].


bronchus connective tissue

description: A portion of connective tissue that is part of a bronchus [Automatically generated definition].


artery smooth muscle tissue

description: A portion of smooth muscle tissue that is part of an artery [Automatically generated definition].


interalveolar septum

description: A the thin septum that separates adjacent pulmonary alveoli, containing connective tissue constituents of the respiratory tissue and the capillary network of the blood supply of the lung.


Nerve Sheath

description: A protective cover encircling a nerve, nerve fiber or axon.


osteoid

description: Bone tissue that is an unmineralized bone matrix deposited by osteoblasts prior to the mineralization of bone tissue.


layer of muscle tissue

description: Any organ component layer that consists of muscle tissue.


smooth muscle of trachea

description: A portion of smooth muscle tissue that is part of a trachea [Automatically generated definition].


vena cava endothelium

description: An endothelium that is part of a vena cava [Automatically generated definition].


cardiovascular system endothelium

description: An endothelium that is part of the cardiovascular system.


bronchus elastic tissue

description: An elastic tissue that is part of a bronchus [Automatically generated definition].


Arteriole Smooth Muscle Tissue

description: The smooth muscle tissue present in the tunica media which is the middle layer of the wall of an arteriole.


odontoid tissue

description: Skeletal tissue that is part of the exoskeleton and derived from an odontogenic papilla.


Arterial System Smooth Muscle Tissue

description: The smooth muscle tissue present in the tunica media which is the middle layer of the wall of the arterial system.


white adipose tissue

description: Connective tissue consisting of fat-storing cells and arranged in lobular groups or along minor blood vessels[MP,modified].


Fat pad

description: Encapsulated adipose tissue within the body.


enamel

description: A dentine-like hypermineralized substance that covers the tooth tip. Enamel's primary mineral is hydroxylapatite, which is a crystalline calcium phosphate. Unlike dentin and bone, enamel does not contain collagen. Instead, it has two unique classes of proteins called amelogenins and enamelins[WP].


elastic cartilage tissue

description: Cartilage tissue that is flexible and contains abundant elastic fibers.


tunica media of artery

description: A tunica media that is part of a artery.


bronchus smooth muscle

description: A portion of smooth muscle tissue that is part of a bronchus [Automatically generated definition].


dentine

description: Collagen-rich odontogenic tissue characteristic of teeth and tooth-like skeletal elements (e.g., odontodes); mature dentine is mineralized and develops from predentine tissue; often (but not always) tubular and acellular.


trabecular network of bone

description: The network of intersecting plates and spicules in cancellous bone which form a meshwork of intercommunicating spaces filled with blood vessels and marrow; in mature bone, the trabeculae are aligned in parallel with the lines of major compressive or tensile force.


loose connective tissue

description: Irregular connective tissue, the intercellular matrix of which contains a sparse irregular network of collagen and elastic fiber bundles. Examples: areolar tissue, neuroglial tissue, mucoid tissue.


Extracellular Matrix

description: The extracellular matrix is a network of fibers that hold cells together. It is found within the extracellular space and in association with the basement membrane of the cell surface. It promotes cellular proliferation and provides a supporting structure to which cells or cell lysates in culture dishes adhere. It is broken down during normal physiological and disease processes such as bone remodeling, embryogenesis, cancer, and arthritis.


Malignant neoplasm of exocervix

description: A malignant neoplasm that affects the exocervix.


name: negative regulation melanotic encapsulation of foreign target

description: Any process that stops, prevents or reduces the frequency, rate or extent of melanotic encapsulation of foreign target.


description: Catalysis of the reaction: acetyl-CoA + N-terminal L-alanyl-peptide = CoA + H+ + N-terminal N-alpha-acetyl-L-alanyl-peptide.


Carpometacarpal Joint 2

description: A plane joint primarily between the second metacarpal and the trapezoid, which also connects with the trapezium and capitate.


name: positive regulation of spinal cord association neuron differentiation

description: Any process that activates or increases the frequency, rate or extent of spinal cord association neuron differentiation.


name: regulation of spinal cord association neuron differentiation

description: Any process that modulates the frequency, rate or extent of spinal cord association neuron differentiation.


name: negative regulation of spinal cord association neuron differentiation

description: Any process that stops, prevents or reduces the frequency, rate or extent of spinal cord association neuron differentiation.


carboxamidine

Compounds having the structure RC(=NR)NR2. The term is used as a suffix in systematic nomenclature to denote the -C(=NH)NH2 group including its carbon atom.


snRNA pseudouridine synthesis

description: The intramolecular conversion of uridine to pseudouridine in an snRNA molecule.


D-arabinonolactonase activity

description: Catalysis of the reaction: D-arabinono-1,4-lactone + H2O = D-arabinonate + H+.


pheophorbidase activity

description: Catalysis of the reaction: pheophorbide a + H2O = pyropheophorbide a + methanol + CO2. The reaction occurs in two steps; pheophoridase catalyzes the conversion of pheophorbide a to a precursor of pyropheophorbide a, C-13(2)-carboxylpyropheophorbide a, by demethylation, and then the precursor is decarboxylated non-enzymatically to yield pyropheophorbide a.


name: mycophenolic acid acyl-glucuronide esterase activity

description: Catalysis of the reaction: mycophenolic acid O-acyl-glucuronide(1-) + H2O = mycophenolate + H+ + D-glucopyranuronate.


sialate 4-O-acetylesterase activity

description: Catalysis of the reaction: H2O + N-acetyl-4-O-acetylneuraminate = acetate + H+ + N-acetylneuraminate.


name: all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity

description: Catalysis of the reaction: H2O + all-trans-retinyl ester = 11-cis-retinol + fatty acid.


Gly-tRNA(Ala) hydrolase activity

description: Catalysis of the hydrolysis of misacylated Gly-tRNA(Ala).


sialate O-acetylesterase activity

description: Catalysis of the reaction: N-acetyl-O-acetylneuraminate (free or glycosidically bound) + H2O = N-acetylneuraminate + acetate.


description: Catalysis of the reaction: a long-chain-acyl ethyl ester + H2O = a long-chain carboxylic acid + ethanol.


acetylajmaline esterase activity

description: Catalysis of the reactions: 17-O-acetylajmaline + H2O = ajmaline + acetate, and 17-O-acetylnorajmaline + H2O = norajmaline + acetate.


pectinesterase activity

description: Catalysis of the reaction: pectin + n H2O = n methanol + pectate.


tropinesterase activity

description: Catalysis of the reaction: atropine + H2O = H+ + tropate + tropine.


acetylxylan esterase activity

description: Catalysis of the deacetylation of xylans and xylo-oligosaccharides.


description: Catalysis of the reaction: H2O + poly[(R)-3-hydroxyoctanoate](n) = poly[(R)-3-hydroxyoctanoate](x) + poly[(R)-3-hydroxyoctanoate](n-x); x is 1-5.


fusarinine-C ornithinesterase activity

description: Catalysis of the reaction: N5-acyl-L-ornithine ester + H2O = N5-acyl-L-ornithine + an alcohol.


steroid-lactonase activity

description: Catalysis of the reaction: H2O + testololactone = H+ + testolate.


acylcarnitine hydrolase activity

description: Catalysis of the reaction: O-acylcarnitine + H2O = a fatty acid + L-carnitine.


triacetate-lactonase activity

description: Catalysis of the reaction: H2O + triacetate lactone = triacetate.


phosphatidylinositol deacylase activity

description: Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol + H2O = 1-acyl-sn-glycero-3-phospho-D-myo-inositol + a carboxylate + H+.


name: L-ascorbate 6-phosphate lactonase activity

description: Catalysis of the reaction: L-ascorbate 6-phosphate + H2O = 3-keto-L-gulonate 6-phosphate.


juvenile-hormone esterase activity

description: Catalysis of the reaction: methyl (2E,6E)-(10R,11S)-10,11-epoxy-3,7,11-trimethyltrideca-2,6-dienoate + H2O = (2E,6E)-(10R,11S)-10,11-epoxy-3,7,11-trimethyltrideca-2,6-dienoate + methanol. A carboxylesterase that hydrolyzes the ester linkage of juvenile hormone.


endosulfan lactone lactonase activity

description: Catalysis of the reaction: endosulfan lactone + H2O = endosulfan hydroxycarboxylate + H+.


description: Catalysis of the removal of acetylesters (as acetate) from galacturonic acid residues in the backbone of rhamnogalacturonan.


description: Catalysis of the reaction: 2-acetyl-1-alkyl-sn-glycerol + H2O = 1-alkyl-sn-glycerol + acetate + H+.


Ala-tRNA(Thr) hydrolase activity

description: Catalysis of the hydrolysis of misacylated ala-tRNA(thr).


description: Catalysis of the reaction: chitooligosaccharide with N-acetylglucosamine at nonreducing terminal + H2O = chitooligosaccharide with glucosamine at nonreducing terminal + acetate. This reaction is the deacetylation of a chitooligosaccharide at the nonreducing N-acetylglucosamine residue; chitooligosaccharide are composed of (1->4)-linked D-glucosamine (GlcN) and N-acetyl-D-glucosamine (GlcNAc) in varying proportions.


1,4-lactonase activity

description: Catalysis of the reaction: H2O + a 1,4-lactone = a 4-hydroxyacid.


description: Catalysis of the reaction: bis(2-ethylhexyl)phthalate + H2O = 2-ethylhexan-1-ol + 2-ethylhexyl phthalate + H+.


orsellinate-depside hydrolase activity

description: Catalysis of the reaction: H2O + orsellinate depside = 2 o-orsellinate + H+.


feruloyl esterase activity

description: Catalysis of the reaction: feruloyl-polysaccharide + H2O = ferulate + polysaccharide.


cephalosporin-C deacetylase activity

description: Catalysis of the reaction: cephalosporin C + H2O = acetate + deacetylcephalosporin C + H+.


name: primary fluorescent dioxobilin-type chlorophyll catabolite methylesterase activity

description: Catalysis of the reaction: H2O + primary fluorescent dioxobilin-type chlorophyll catabolite = H+ + methanol + O13(4)-desmethyl pFCC.


alpha-amino-acid esterase activity

description: Catalysis of the reaction: an alpha-amino acid ester + H2O = an alpha-amino acid + an alcohol.


6-acetylglucose deacetylase activity

description: Catalysis of the reaction: 6-acetyl-D-glucose + H2O = D-glucose + acetate + H+.


tannase activity

description: Catalysis of the reaction: digallate + H2O = 2 gallate + H+.


cetraxate benzylesterase activity

description: Catalysis of the reaction: benzyl cetraxate + H2O = benzyl alcohol + cetraxate + H+.


Ala-tRNA(Pro) hydrolase activity

description: Catalysis of the hydrolysis of misacylated Ala-tRNA(Pro).


palmitoleyl hydrolase activity

description: Catalysis of a hydrolase reaction that removes a palmitoleyl moiety, a 16-carbon monounsaturated fatty acid (C16:1), from some substrate.


description: Catalysis of the reaction: (R)-3-[(R)-3-hydroxybutanoyloxy]butanoate + H2O = 2 (R)-3-hydroxybutanoate + H+.


retinyl-palmitate esterase activity

description: Catalysis of the reaction: retinyl palmitate + H2O = retinol + palmitate + H+.


lactonohydrolase activity

description: Catalysis of the hydrolysis of lactone rings (intramolecular cyclic esters) to produce a hydroxyl group and a carboxyl group.


name: methyl indole-3-acetate esterase activity

description: Catalysis of the reaction: methyl indole-3-acetate + H2O = indole-3-acetate + methanol + H+.


description: Catalysis of the reaction: 1-oxa-2-oxocycloheptane + H2O = 6-hydroxyhexanoate.


Ser(Gly)-tRNA(Ala) hydrolase activity

description: Catalysis of the hydrolysis of misacylated Ser-tRNA(Ala) and Gly-tRNA(Ala).


dihydrocoumarin hydrolase activity

description: Catalysis of the reaction: 3,4-dihydrocoumarin + H2O = 3-(2-hydroxyphenyl)propanoate + H+.


description: Catalysis of the reaction: H2O + poly[(R)-3-hydroxybutanoate](n) = poly[(R)-3-hydroxybutanoate](x) + poly[(R)-3-hydroxybutanoate](n-x); x is 1-5.


L-seryl-tRNA(Thr) hydrolase activity

description: Catalysis of the hydrolysis of misacylated Ser-tRNA(Thr).


name: all-trans-retinyl-palmitate hydrolase, 11-cis retinol forming activity

description: Catalysis of the reaction: H2O + all-trans-retinyl palmitate = 11-cis-retinol + H+ + palmitate.


name: 1-16:0-2-18:2-phosphatidylcholine sn-1 acylhydrolase activity

description: Catalysis of the reaction: 1-palmitoyl-2-linoleoyl-phosphatidylcholine + H2O = 1-linoleoyl-sn-glycero-3-phosphocholine + hexadecanoate + H+.


name: vinylacetate caboxylester hydrolase activity

description: Catalysis of the reaction: but-3-enoate + H2O = allyl alcohol + formate.


deoxylimonate A-ring-lactonase activity

description: Catalysis of the reaction: deoxylimonoate + H2O = deoxylimononate D-ring-lactone + H+.


wax-ester hydrolase activity

description: Catalysis of the reaction: a wax ester + H2O = a long-chain alcohol + a long-chain carboxylate.


description: Catalysis of the reaction: 2-oxo-3-(5-oxofuran-2-ylidene)propanoate + H2O = 3-maleylpyruvate + H+.


phorbol-diester hydrolase activity

description: Catalysis of the reaction: H2O + phorbol 12,13-dibutanoate = butanoate + H+ + phorbol 13-butanoate.


4-sulfomuconolactone hydrolase activity

description: Catalysis of the reaction: (5-oxo-2-sulfonato-2,5-dihydrofuran-2-yl)acetate + H2O = maleylacetate + sulfite + 2 H+.


5-valerolactone hydrolase activity

description: Catalysis of the reaction: 5-valerolactone + H2O = 5-hydroxyvalerate.


prenylcysteine methylesterase activity

description: Catalysis of the reaction: protein C-terminal S-farnesyl-L-cysteine methyl ester + H2O = protein C-terminal S-farnesyl-L-cysteine + methanol + H+.


butyrolactone hydrolase activity

description: Catalysis of the reaction: butyrolactone + H2O = 4-hydroxybutanoate.


L-rhamnono-1,4-lactonase activity

description: Catalysis of the reaction: L-rhamnono-1,4-lactone + H2O = L-rhamnonate + H+.


pheophytinase activity

description: Catalysis of the reaction: pheophytin + H2O = phytol + pheophorbide.


sialate 9-O-acetylesterase activity

description: Catalysis of the reaction: H2O + N-acetyl-9-O-acetylneuraminate = acetate + H+ + N-acetylneuraminate.


diphthine methylesterase activity

description: Catalysis of the reaction: diphthine methyl ester + H2O = diphthine + H+ + methanol.


gluconolactonase activity

description: Catalysis of the reaction: D-glucono-1,5-lactone + H2O = D-gluconate.


description: Catalysis of the reaction: H2O + a 1,3-diglyceride = a monoglyceride + a fatty acid.


name: protein C-terminal methylesterase activity

description: Catalysis of the reaction: C-terminal protein amino acid methyl ester + H2O = protein amino acid + methanol.


short-chain carboxylesterase activity

description: Catalysis of the reaction: a carboxylic ester + H2O = an alcohol + a carboxylic anion, where the carboxylic chain has 8 or fewer carbon atoms.


Cys-tRNA(Pro) hydrolase activity

description: Catalysis of the hydrolysis of misacylated Cys-tRNA(Pro).


methyl jasmonate esterase activity

description: Catalysis of the reaction: a methyl jasmonate + H2O = a jasmonic acid + methanol.


4-methyloxaloacetate esterase activity

description: Catalysis of the reaction: 4-methoxy-2,4-dioxobutanoate + H2O = H+ + methanol + oxaloacetate.


protein methylesterase activity

description: Catalysis of the reaction: protein amino acid methyl ester + H2O = protein amino acid + methanol.


description: Catalysis of the reaction: [X]-4-O-methyl-D-glucuronic acid + H2O = [X]-OH + methyl-D-glucuronic acid. This reaction is the hydrolysis of the ester linkage between 4-O-methyl-D-glucuronic acid (MeGlcA) and an alcohol (-OH) group attached to a molecule, denoted here as [X].


description: Catalysis of the reaction: 11-cis-retinyl palmitate + H2O = 11-cis-retinol + H+ + palmitate.


pheophytinase b activity

description: Catalysis of the reaction: pheophytin b + H2O = H+ + pheophorbide b + phytol.


sulfolactone hydrolase activity

description: Catalysis of the reaction: 4-sulfolactone + OH- = HSO3(-) + maleylacetate.


description: Catalysis of the reaction: 5-(4-acetoxybut-1-ynyl)-2,2'-bithiophene + H2O = 5-(4-hydroxy-but-1-ynyl)-2,2'-bithiophene + acetate + H+.


name: all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity

description: Catalysis of the reaction: all-trans-retinyl palmitate + H2O = all-trans-retinol + H+ + palmitate.


phosphatidyl phospholipase B activity

description: Catalysis of the reaction: 2 H2O + a phosphatidylcholine = sn-glycero-3-phosphocholine + 2 H+ + 2 a carboxylate.


acetylsalicylate deacetylase activity

description: Catalysis of the reaction: acetylsalicylate + H2O = acetate + H+ + salicylate.


description: Catalysis of the reaction: H2O + an N-acyl-L-homoserine lactone = H+ + an N-acyl-L-homoserine.


trans-permethrin hydrolase activity

description: Catalysis of the reaction: (-)-trans-permethrin + H2O = H+ + (3-phenoxyphenyl)methanol + (1S,3R)-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate.


description: Catalysis of the reaction: H2O + polyneuridine aldehyde = 16-epivellosimine + CO2 + methanol.


D-leucyl-tRNA(Leu) deacylase activity

description: Catalysis of the reaction: D-leucyl-tRNA(Leu) = D-leucine + tRNA(Leu). Hydrolysis of the removal of D-leucine from residues in charged tRNA(Leu).


L-arabinonolactonase activity

description: Catalysis of the reaction: L-arabinono-1,4-lactone + H2O = L-arabinonate + H+.


3-oxoadipate enol-lactonase activity

description: Catalysis of the reaction: 3-oxoadipate enol-lactone + H2O = 3-oxoadipate.


heparan sulfate N-deacetylase activity

description: Catalysis of the reaction: H2O + [heparan sulfate]-N-acetyl-alpha-D-glucosamine = acetate + H+ + [heparan sulfate]-alpha-D-glucosamine.


limonin-D-ring-lactonase activity

description: Catalysis of the reaction: limonoate D-ring-lactone + H2O = limonoate.


chlorogenate hydrolase activity

description: Catalysis of the reaction: chlorogenate + H2O = (-)-quinate + cis-caffeate + H+.


uronolactonase activity

description: Catalysis of the reaction: D-glucurono-6,2-lactone + H2O = D-glucuronate.


brefeldin A esterase activity

description: Catalysis of the hydrolysis of brefeldin A to produce brefeldin A acid. Brefeldin A is also known as gamma,4-dihydroxy-2-(6-hydroxy-1-heptenyl)-4-cyclopentanecrotonic acid lambda-lactone.


galactolipase activity

description: Catalysis of the reaction: 1,2-diacyl-3-beta-D-galactosyl-sn-glycerol + 2 H2O = 3-beta-D-galactosyl-sn-glycerol + 2 carboxylates.


actinomycin lactonase activity

description: Catalysis of the reaction: actinomycin + H2O = actinomycinic monolactone.


methyl salicylate esterase activity

description: Catalysis of the reaction: methyl salicylate + H2O = salicylic acid + methanol + H+.


4-pyridoxolactonase activity

description: Catalysis of the reaction: 4-pyridoxolactone + H2O = 4-pyridoxate + H+.


description: Catalysis of the reaction: 5-(3,4-diacetoxybut-1-ynyl)-2,2'-bithiophene + H2O = 5-(3-hydroxy-4-acetoxybut-1-ynyl)-2,2'-bithiophene + acetate + H+.


description: Catalysis of the reaction: H2O + a 1,2-diacyl-sn-glycerol = a monoglyceride + a fatty acid.


name: pimelyl-[acyl-carrier protein] methyl ester esterase activity

description: Catalysis of the reaction: pimelyl-[acyl-carrier protein] methyl ester + H2O = pimelyl-[acyl-carrier protein] + methanol.


description: Catalysis of the reaction: 1-18:1-2-16:0-monogalactosyldiacylglycerol + H2O = sn-1-lyso-2-16:0-monogalactosyldiacylglycerol + oleate + H+.


description: Catalysis of the reaction: protein L-glutamate O(5)-methyl ester + H2O = protein L-glutamate + methanol.


hormone-sensitive lipase activity

description: Catalysis of the reactions: diacylglycerol + H2O = monoacylglycerol + a carboxylate; triacylglycerol + H2O = diacylglycerol + a carboxylate; and monoacylglycerol + H2O = glycerol + a carboxylate.


acyloxyacyl hydrolase activity

description: Catalysis of the reaction: 3-(acyloxy)acyl group of bacterial toxin = 3-hydroxyacyl group of bacterial toxin + a fatty acid.


description: Catalysis of the reaction: H2O + N-acetyl-D-galactosaminoglycan = acetate + D-galactosaminoglycan.


acetylesterase activity

description: Catalysis of the reaction: an acetic ester + H2O = an alcohol + acetate.


xylono-1,4-lactonase activity

description: Catalysis of the reaction: D-xylono-1,4-lactone + H2O = D-xylonate.


pectin acetylesterase activity

description: Catalysis of the reaction: pectin + H2O = pectate + acetate. This reaction is the hydrolysis of acetyl esters of pectin, producing pectate, partially esterified pectin.


carboxymethylenebutenolidase activity

description: Catalysis of the reaction: 4-carboxymethylenebut-2-en-4-olide + H2O = 4 oxohex-2-enedioate.


sinapine esterase activity

description: Catalysis of the reaction: O-sinapoylcholine + H2O = choline + H+ + sinapate.


cutinase activity

description: Catalysis of the reaction: cutin + H2O = cutin monomers.


aclacinomycin T methylesterase activity

description: Catalysis of the reaction: aclacinomycin T(1+) + H2O = 15-demethylaclacinomycin T + methanol + H+.


Ser-tRNA(Ala) hydrolase activity

description: Catalysis of the hydrolysis of misacylated Ser-tRNA(Ala).


Genital Human Papillomavirus Infection

description: Infection of the genitalia by human papillomavirus.


name: hercynylcysteine sulfoxide synthase activity

description: Catalysis of the reaction: L-cysteine + N-alpha,N-alpha,N-alpha-trimethyl-L-histidine (hercynine) + O2 = hercynylcysteine sulfoxide + H2O.


name: ramus muscularis of glossopharyngeus nerve

description: Branchiomotor branch of the glossopharyngeus nerve innervating the m. subarcuales rectus I.


anaerobic L-alanine catabolic process

description: The anaerobic chemical reactions and pathways resulting in the breakdown of L-alanine, yielding energy in the form of ATP.


alanine biosynthetic process

description: The chemical reactions and pathways resulting in the formation of alanine, 2-aminopropanoic acid.


D-alanine metabolic process

description: The chemical reactions and pathways involving D-alanine, the D-enantiomer of the amino acid alanine, i.e. (2R)-2-aminopropanoic acid.


name: L-alanine oxidation to pyruvate via D-alanine

description: The chemical reactions and pathways resulting in the breakdown of L-alanine to pyruvate, with D-alanine as an intermediate.


name: beta-alanine catabolic process to L-alanine

description: The chemical reactions and pathways resulting in the breakdown of beta-alanine into other compounds, including L-alanine.


name: L-alanine catabolic process, by transamination

description: The chemical reactions and pathways resulting in the breakdown of L-alanine by transamination.


name: L-alanine oxidation to D-lactate and ammonia

description: The chemical reactions and pathways resulting in the breakdown of L-alanine to D-lactate and ammonia.


D-alanine biosynthetic process

description: The chemical reactions and pathways resulting in the formation of D-alanine, the D-enantiomer of the amino acid alanine, i.e (2R)-2-aminopropanoic acid.


D-alanine catabolic process

description: The chemical reactions and pathways resulting in the breakdown of D-alanine, the D-enantiomer of the amino acid alanine.


name: arginine catabolic process to alanine via ornithine

description: The chemical reactions and pathways resulting in the breakdown of arginine into other compounds, including alanine, via ornithine.


name: voltage-gated sodium channel activity involved in SA node cell action potential

description: Enables the transmembrane transfer of a sodium ion by a voltage-gated channel through the plasma membrane of an SA node cardiac muscle cell contributing to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.


name: arabitol transmembrane transporter activity

description: Enables the transfer of an arabitol from one side of a membrane to the other. Arabitol is the pentitol derived from arabinose or lyxose by reduction of the aldehyde group. The D enantiomer is present in lichens and mushrooms.


Iatrogenic Hypoparathyroidism

description: Hypoparathyroidism resulting from medical treatment or intervention.


Acquired Hypoparathyroidism

description: Hypoparathyroidism, the cause of which is not present at birth.


Hypoparathyroidism, Autosomal Recessive

description: Hypoparathyroidism associated with homozygous mutation(s) in the PTH gene, which encodes parathyroid hormone, or in the GCM2 gene, which encodes chorion-specific transcription factor GCMb.


Transient neonatal hypoparathyroidism

description: A disorder of decreased production of parathyroid hormone by the parathyroid gland in a newborn. It is due to maternal hyperparathyroidism. It may be characterized by hypocalcemic seizures in the first weeks of life.


Primary hypoparathyroidism

description: Abnormally low levels of parathyroid hormone due to a disorder originating within the parathyroid glands.


2,4,6-trinitrotoluene catabolic process

description: The chemical reactions and pathways resulting in the breakdown of 2,4,6-trinitrotoluene, 1-methyl-2,4,6-trinitrobenzene, a highly explosive pale yellow crystalline solid.


trinitrotoluene catabolic process

description: The chemical reactions and pathways resulting in the breakdown of trinitrotoluene, a methylated benzene entity with three NO2 groups attached to it. This includes the explosive TNT, 1-methyl-2,4,6-trinitrobenzene.


name: anaerobic 2,4,6-trinitrotoluene catabolic process

description: The chemical reactions and pathways resulting in the breakdown of 2,4,6-trinitrotoluene, 1-methyl-2,4,6-trinitrobenzene, a highly explosive pale yellow crystalline solid, in the absence of oxygen.


name: clearance of foreign intracellular nucleic acids

description: A defense process that protects an organism from DNA or RNA from an invading organism.


suppression of viral release by host

description: A process in which a host organism stops, prevents or reduces the frequency, rate or extent of the release of a virus with which it is infected, from its cells.


name: antimicrobial humoral immune response mediated by antimicrobial peptide

description: An immune response against microbes mediated by anti-microbial peptides in body fluid.


name: jasmonic acid and ethylene-dependent systemic resistance

description: The jasmonic acid and ethylene (ethene) dependent process that confers broad spectrum systemic resistance to disease in response to wounding or a pathogen.


cytolysis by host of symbiont cells

description: The killing by an organism of a cell in its symbiont organism by means of the rupture of cell membranes and the loss of cytoplasm. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.


CRISPR-cas system

description: A defense response of that serves to clear host cells of foreign DNA and RNA. It has three distinct stage: acquisition of foreign DNA by integration into CRISPR loci in the host chromosome, CRISPR RNA (crRNA) biogenesis, and target interference. CRISPR stands for Clustered Regularly Interspaced Short Palindromic Repeat, which describes the nature of the loci.


induced systemic resistance

description: A response to non-pathogenic bacteria that confers broad spectrum systemic resistance to disease that does not depend upon salicylic acid signaling.


name: natural killer cell mediated immune response to tumor cell

description: An immune response mediated by a natural killer cell triggered in response to the presence of a tumor cell.


DNA restriction-modification system

description: A defense process found in many bacteria and archaea that protects the organism from invading foreign DNA by cleaving it with a restriction endonuclease. The organism's own DNA is protected by methylation of a specific nucleotide, which occurs immediately following replication, in the same target site as the restriction enzyme.


suppression of symbiont entry into host

description: Any process in which an organism stops, prevents, or reduces the frequency, rate or extent to which it enters into a second organism, where the two organisms are in a symbiotic interaction.


defense response to host

description: Reactions triggered in response to the presence of a host that act to protect or prevent damage to the symbiont.


defense response to symbiont

description: Reactions triggered in response to the presence of a symbiont that act to protect or prevent damage to the host.


antiviral innate immune response

description: A defense response against viruses mediated through an innate immune response. An innate immune response is mediated by germline encoded components that directly recognize components of potential pathogens.


name: male-specific defense response to bacterium

description: A set of reactions, specific to males, that are triggered in response to the presence of a bacterium that act to protect the cell or organism.


clearance of foreign intracellular DNA

description: A defense process that protects an organism from invading foreign DNA.


natural killer cell cytokine production

description: Any process that contributes to cytokine production by a natural killer cell.


defense response to oomycetes

description: Reactions triggered in response to the presence of oomycetes that act to protect the cell or organism.


antifungal innate immune response

description: An defense response against a fungus mediated through an innate immune response. An innate immune response is mediated by germline encoded components that directly recognize components of potential pathogens.


name: natural killer cell mediated cytotoxicity directed against tumor cell target

description: The directed killing of a tumor cell by a natural killer cell through the release of granules containing cytotoxic mediators or through the engagement of death receptors.


antibacterial innate immune response

description: An defense response against a bacteria mediated through an innate immune response. An innate immune response is mediated by germline encoded components that directly recognize components of potential pathogens.


name: male-specific antibacterial humoral response

description: An immune response against bacteria, specific to males and mediated through a body fluid.


defense response to parasitic plant

description: Reactions triggered in response to the presence of a parasitic plant that act to protect an organism.


hemolymph coagulation

description: Any process in which factors in the hemolymph (the invertebrate equivalent of vertebrate blood and lymph) precipitate into insoluble clots in order to prevent loss of body fluid, and at the same time prevent the movement of microbes. Hemolymph coagulation is also part of the invertebrate humoral immune response.


name: melanotic encapsulation of foreign target

description: Formation of a multilayered, melanized sheath of cells around a foreign invader.


systemic acquired resistance

description: The salicylic acid-mediated response to a pathogen which confers broad spectrum resistance.


melanization defense response

description: The blackening of the wounded area of the cuticle or the surface of invading pathogens, parasites or parasitoids, resulting from a proteolytic cascade leading to the de novo synthesis and deposition of melanin.


innate immunity memory response

description: An immune response mediated by the innate immune system and directed against a previously encountered immunologic stimulus, being quicker and quantitatively better compared with the initial response to that stimulus.


innate immune response

description: Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens.


name: defense response against perturbation of plasma membrane integrity

description: The cellular processes and signaling pathways by which a cell responds to disruption of the integrity of its plasma membrane by another organism. Some toxins produced by other organisms can form pores in membranes, or affect the membrane permeability.


age-related resistance

description: An innate immune response that is positively correlated with host plant development. As a plant develops, its innate resistance to pathogenic infections increases. The mechanisms involved in age-related resistance differ in nature or in aspects of regulation from the hypersensitive response (HR), systemic acquired resistance (SAR), or induced systemic resistance (ISR).


clearance of foreign intracellular RNA

description: A defense process that protects an organism from invading foreign RNA.


pigment granule membrane

description: Any membrane that is part of a pigment granule.


name: epicardium-derived cardiac vascular smooth muscle cell development

description: The process whose specific outcome is the progression of a cardiac vascular smooth muscle cell that was derived from the epicardium over time, from its formation to the mature state.


description: Catalysis of the reaction: cis-2-chloro-4-carboxymethylenebut-2-en-1,4-olide = trans-2-chloro-4-carboxymethylenebut-2-en-1,4-olide.


Circumscribed storiform collagenoma

description: A benign skin tumor characterized as a small, dome-shaped dermal nodule composed of fibroblasts in a dense collagenous background with storiform organization.  Rarely, multiple lesions can occur in connection with Cowden's disease.


Senile nevus

description: A benign skin lesion consisting of a cluster of capillaries at the surface of the skin, forming a red papular lesion.


chlorobenzophenone

A member of the class of benzophenones that is any substituted benzophenone in which at least one of the substituents is a chlorine.


name: detection of reduced oxygen by carotid body chemoreceptor signaling

description: The process in which information about the levels of oxygen are received and are converted to a molecular signal by chemoreceptors in a carotid body.


saddle joint

description: In a saddle joint (sellar joint, articulation by reciprocal reception) the opposing surfaces are reciprocally concave-convex.


epithelium of forearm

description: An epithelium that is part of a lower arm [Automatically generated definition].


name: positive regulation of bone trabecula formation

description: Any process that activates or increases the frequency, rate or extent of bone trabecula formation.


elastin biosynthetic process

description: The chemical reactions and pathways resulting in the formation of elastin, a fibrous glycoprotein found in elastic tissues such as the walls of arteries.


Elevated AFP-L3

category: biolink:PhenotypicFeature biolink:DiseaseOrPhenotypicFeature biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing

description: A finding indicating that elevated concentrations of alpha-fetoprotein (AFP) fraction L3 (AFP-L3) were detected in a sample. AFP-L3 represents a glycoform variant of AFP that is highly reactive with Lens culinaris-expressed agglutinin (LCA) due to the presence of an extra alpha-(1-6) fucose attached to the N-acetylglucosamine modification present in AFP.


description: Catalysis of the reaction: 4,4'-dihydroxy-alpha-methylstilbene + O2 = 4-hydroxybenzaldehyde + 4-hydroxyacetophenone + 2 H+ + 2 e-.


collagen type VII trimer

description: A collagen homotrimer of alpha1(VII) chains; type VII collagen triple helices form antiparallel dimer, which in turn associate laterally to form anchoring fibrils that connect type IV collagen in the basal lamina to plaques in the underlying connective tissue. It binds laminin.


anilines

Any  aromatic amine that is benzene carrying at least one amino substituent and its substituted derivatives.


(R)-aminoglutethimide

The (3R)-enantiomer of aminoglutethimide.


isoflavonoid catabolic process

description: The chemical reactions and pathways resulting in the breakdown of isoflavonoids, a group of water-soluble phenolic derivatives, isomeric with flavonoids.


cinnamic acid catabolic process

description: The chemical reactions and pathways resulting in the breakdown of cinnamic acid, 3-phenyl-2-propenoic acid.


name: p-hydroxyphenyl lignin catabolic process

description: The chemical reactions and pathways resulting in the breakdown of p-hydroxyphenyl lignin.


anaerobic lignin catabolic process

description: The chemical reactions and pathways resulting in the breakdown of lignin in the absence of oxygen. Lignin is a class of polymers of phenylpropanoid units.


chalcone catabolic process

description: The chemical reactions and pathways resulting in the breakdown of chalcone, phenyl steryl ketone or its hydroxylated derivatives.


eugenol catabolic process

description: The chemical reactions and pathways resulting in the breakdown of eugenol, a colorless, aromatic, liquid hydrocarbon (C10H12O2) found in clove oil.


name: isoflavonoid phytoalexin catabolic process

description: The chemical reactions and pathways resulting in the breakdown of isoflavonoid phytoalexins, a group of water-soluble phenolic derivatives isomeric with flavonoids that possess antibiotic activity and are produced by plant tissues in response to infection.


cinnamic acid ester catabolic process

description: The chemical reactions and pathways resulting in the breakdown of ester derivatives of cinnamic acid, phenylpropenoic acid.


lignin catabolic process

description: The chemical reactions and pathways resulting in the breakdown of lignins, a class of polymers of phenylpropanoid units.


guaiacyl lignin catabolic process

description: The chemical reactions and pathways resulting in the breakdown of guaiacyl lignin.


name: negative regulation of colon smooth muscle contraction

description: Any process that stops, prevents or reduces the frequency, rate or extent of colon smooth muscle contraction.


name: visual perception involved in equilibrioception

description: The series of events during equilibrioception required for an organism to receive a visual stimulus, convert it to a molecular signal, and recognize and characterize the signal. Visual input plays an important role in the ability of an organism to perceive its orientation with respect to gravity.


irregular bone

description: The irregular bones are bones which, from their peculiar form, cannot be grouped as long bone, short bone, flat bone or sesamoid bone. Irregular bones serve various purposes in the body, such as protection of nervous tissue, affording multiple anchor points for skeletal muscle attachment (as with the sacrum), and maintaining pharynx and trachea support, and tongue attachment (such as the hyoid bone). They consist of cancellous tissue enclosed within a thin layer of compact bone. The irregular bones are: the vertebrC&, sacrum, coccyx, temporal, sphenoid, ethmoid, zygomatic, maxilla, mandible, palatine, inferior nasal concha, and hyoid.


vertebra

description: The ossified form of a vertebral element, a skeletal element that forms around the notochord and is part of the vertebral column.


inferior nasal concha

description: A turbinal located on the maxilla bone.


name: negative regulation of sevenless signaling pathway

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the sevenless signaling pathway.


description: Catalysis of the reaction: phenanthrene-4-carboxylate + 2 H+ + 2 e- + O2 = cis-3,4-phenanthrenedihydrodiol-4-carboxylate.


fluorenes

An ortho-fused polycyclic arene in which the skeleton is composed of two benzene rings ortho-fused to cyclopentane.


name: positive regulation of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination

description: Any process that activates or increases the frequency, rate or extent of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination.


name: positive regulation of meiotic DNA double-strand break formation

description: Any process that activates or increases the frequency, rate or extent of meiotic DNA double-strand break formation.


name: positive regulation of antibody-dependent cellular cytotoxicity

description: Any process that activates or increases the frequency, rate or extent of antibody-dependent cellular cytotoxicity.


Primary Insomnia

description: A sleep disorder characterized by difficulty initiating or maintaining sleep; this difficulty does not occur in the context of another sleep disorder and is not etiologically linked to a mental disorder, substance use, or a general medical condition.


GAC codon-amino acid adaptor activity

description: A triplet codon-amino acid adaptor activity that recognizes a GAC codon.


tetrol

A polyol that contains 4 hydroxy groups.


A hydroxycalciol that is a synthetic fluorinated and deuterated analogue of vitamin D3 which exhibits vitamin D receptor superagonist and anti-cancer activity.


1alpha,23(S),25-trihydroxyvitamin D3

A hydroxycalciol that consists of vitamin D3 (calciol) bearing additional hydroxy substituents at positions 1, 23 and 25 (with 1alpha,23S-configuration). An intermediate in the degradation pathway of 1alpha,25-(OH)2D3.


(20S,23,24)-trihydroxyvitamin D3

A hydroxycalciol that consists of vitamin D3 (calciol) carrying additional hydroxy groups  at positions 20 (with S-configuration), 23 and 24.


A vitamin D that is 19-norcalcitriol carrying an additional 3-hydroxypropyl substituent at position 2. A synthetic analogue of vitamin D, it exhibits anticancer properties.


nordihydroguiaretic acid

A tetrol that is butane which is substituted at positions 2 and 3 by 3,4-dihydroxybenzyl groups. Masoprocol, the meso-form found in the leaves of the creosote bush (Larrea divaricata), is a potent lipoxygenase inhibitor.


eldecalcitol

A hydroxycalciol that is calcitriol with a 3-hydroxypropoxy group at position 2.


(20S,23,25)-trihydroxyvitamin D3

A hydroxycalciol that consists of vitamin D3 (calciol) carrying additional hydroxy groups at positions 20 (with S-configuration), 23 and 25.


A hydroxycalciol that is calcitriol with a 4-hydroxybutoxy group at position 2.


name: diphosphate-purine nucleoside kinase activity

description: Catalysis of the reaction: diphosphate + a purine nucleoside = monophosphate + a purine mononucleotide.


name: germarium-derived female germ-line cyst formation

description: Formation, in a germarium, of a group of interconnected cells derived from a single female gonial founder cell (a cystoblast). The germarium is the most anterior portion of an insect ovariole. An example of this process is found in Drosophila melanogaster.


Cor triloculare

description: A congenital anatomic anomaly in which the heart has only three chambers.


name: Splenic Manifestation of Chronic Lymphocytic Leukemia

description: Infiltration of the spleen by chronic lymphocytic leukemia. It primarily involves the white pulp.


aspartate kinase activity

description: Catalysis of the reaction: L-aspartate + ATP = 4-phospho-L-aspartate + ADP + H+.


amino acid kinase activity

description: Catalysis of the transfer of a phosphate group, usually from ATP, to an amino acid substrate.


glutamate 5-kinase activity

description: Catalysis of the reaction: L-glutamate + ATP = L-glutamyl 5-phosphate + ADP + H+.


homoserine kinase activity

description: Catalysis of the reaction: L-homoserine + ATP = O-phospho-L-homoserine + ADP + 2 H+.


hydroxylysine kinase activity

description: Catalysis of the reaction: erythro-5-hydroxy-L-lysine + GTP = 5-phosphonooxy-L-lysine + GDP + 2 H+.


description: Catalysis of the reaction: ATP + N-acetyl-L-2-aminoadipate = ADP + N-acetyl-L-2-aminoadipate 6-phosphate.


arginine kinase activity

description: Catalysis of the reaction: L-arginine + ATP = N(omega)-phospho-L-arginine + ADP + 2 H+.


GMP catabolic process to IMP

description: The chemical reactions and pathways resulting in the breakdown of guanosine monophosphate into other compounds, including inosine monophosphate.


Kaposi's sarcoma of oral cavity

description: Kaposi sarcoma arising from the oral cavity.


name: extraglomerular mesangial cell proliferation

description: The multiplication or reproduction of extraglomerular glomerular mesangium cells by cell division, resulting in the expansion of their population. Extraglomerular mesangial cells (also known as lacis cells, Goormaghtigh cells) are light-staining cells in the kidney found outside the glomerulus, near the vascular pole and macula densa.


name: mesonephric extraglomerular mesangial cell proliferation involved in mesonephros development

description: The multiplication or reproduction of extraglomerular glomerular mesangium cells in the mesonephros by cell division, resulting in the expansion of their population. Extraglomerular mesangial cells (also known as lacis cells, Goormaghtigh cells) are light-staining cells in the kidney found outside the glomerulus, near the vascular pole and macula densa.


thoracic vertebra 12

description: The twelfth thoracic vertebra counting from the top down. Note that members of this class are not necessarily homologous[ncit,modified].


name: negative regulation of granulosa cell proliferation

description: Any process that stops, prevents or reduces the frequency, rate or extent of granulosa cell proliferation.


Parotid Gland Lipoma

description: A lipoma that arises from the parotid gland.


name: adenylate cyclase-inhibiting adrenergic receptor signaling pathway

category: biolink:Pathway biolink:OntologyClass biolink:BiologicalProcess biolink:Occurrent biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: An adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway initiated by a ligand binding to an adrenergic receptor, and ending with the regulation of a downstream cellular process.


insect internal sensillum

description: Sensillum that is internal to the animal - i.e. having no part that is part of the cuticle.


insect Bolwig organ

description: Visual organ of the larva. It consists of a dense cluster of 12 ciliated photoreceptor neurons.


name: chanoclavine-I aldehyde biosynthetic process

description: The chemical reactions and pathways resulting in the formation of chanoclavine-I aldehyde. Chanoclavine-I aldehyde is at a branching point in the biosynthetic pathways of fumigaclavine C and ergotamine.


name: negative regulation of positive chemotaxis to cAMP by DIF-2

description: Any process that decreases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of DIF-2. DIF-2 is a chlorinated alkylphenone.


name: positive regulation of epidermal growth factor receptor signaling pathway involved in heart process

description: Any process that activates or increases the frequency, rate or extent of epidermal growth factor receptor signaling pathway involved in heart process.


name: positive regulation of ERBB3 signaling pathway

description: Any process that activates or increases the frequency, rate or extent of ERBB3 signaling pathway.


name: symbiont-mediated suppression of host complement activation by complement sequestering

description: A process by which a symbiont prevents host complement activation by sequestering it away from its surface.


name: symbiont-mediated suppression of host complement activation

description: A process by which a symbiont inhibits or disrupts the normal execution of the activation of complement in its host. The host is defined as the larger of the organisms involved in a symbiotic interaction.


name: symbiont-mediated suppression of host complement activation by activation of host proteases

description: A process by which a symbiont prevents host complement activation by recruiting host proteases, destroying the complement before it has its effect on the symbiont.


name: symbiont-mediated suppression of host complement activation by recruitment of complement control protein

description: A process by which a symbiont prevents the activation of host complement by binding a soluble complement control protein (CCP) of the host and recruiting it to the microbe surface. The normal role of CCPs is to prevent complement activation on 'self' cellular targets. When soluble CCPs are recuited to the surface of a microbe, the complement fails to activate.


name: symbiont-mediated suppression of host complement activation by inactivation of complement proteins

description: A process by which a symbiont disrupts or prematurely activates host complement so that its microbial-destroying activities fail.


name: glutamate dehydrogenase (NADP+) activity

description: Catalysis of the reaction: L-glutamate + H2O + NADP+ = 2-oxoglutarate + NH3 + NADPH + H+.


splenic arteriole

description: A tiny terminal artery that is continuous with the capillaries in the spleen.


spleen central arteriole

description: A blood vessel surrounded by the periarteriolar lymphoid sheath that connects the trabecular artery to the trabecular vein.


penicillar arteriole

description: One of the small straight arteries of the red pulp of the spleen; a branch of the spleen central artery that supplies the red pulp[WP,modified].


PYRAZINE

A diazine that is benzene in which the carbon atoms at positions 1 and 4 have been replaced by nitrogen atoms.


An  oxazolidinone that is 1,3-oxazolidine with an oxo substituent at position 2.


extrathymic T cell differentiation

description: The process in which a precursor cell type acquires the specialized features of a T cell via a differentiation pathway independent of the thymus.


name: old cell tip after activation of bipolar cell growth

description: A cell tip which has existed for at least one complete cell cycle, and at which polarized growth occurs, which is part of a cell that has activated bipolar cell growth (i.e. in which new end take-off, NETO, has taken place). For example, in fission yeast the cell end that existed prior to cell division grows immediately after division, and contains a distinctive complement of proteins including actin cytoskeletal structures.


name: regulation of dehydroaustinol biosynthetic process

description: Any process that modulates the frequency, rate or extent of dehydroaustinol biosynthetic process.


name: negative regulation of dehydroaustinol biosynthetic process

description: Any process that stops, prevents or reduces the frequency, rate or extent of dehydroaustinol biosynthetic process.


mannose-specific flocculation

description: The non-sexual aggregation of single-celled organisms mediated by the binding of cell wall proteins on one cell to mannose residues on the other.


glucarate biosynthetic process

description: The chemical reactions and pathways resulting in the formation of glucarate, the anion of glucaric acid.


glucarate metabolic process

description: The chemical reactions and pathways involving glucarate, the dianion of glucaric acid, an aldaric acid derived from either glucose or gulose. There are two enantiomers L- and D-glucarate.


glucarate catabolic process

description: The chemical reactions and pathways resulting in the breakdown of glucarate, the anion of glucaric acid.


D-glucarate catabolic process

description: The chemical reactions and pathways resulting in the breakdown of D-glucarate, the D-enantiomer of glucarate.


D-glucarate metabolic process

description: The chemical reactions and pathways involving D-glucarate, the D-enantiomer of glucarate. D-glucarate is derived from either D-glucose or L-gulose.


D-glucarate biosynthetic process

description: The chemical reactions and pathways resulting in the formation of D-glucarate, the D-enantiomer of glucarate.


name: (3R)-hydroxyacyl-CoA dehydrogenase (NAD+) activity

description: Catalysis of the reaction: 3R-hydroxyacyl-CoA + NAD+ = 3-oxoacyl-CoA + NADH.


name: deoxyribonuclease IV (phage-T4-induced) activity

description: Catalysis of the endonucleolytic cleavage to 5'-phosphooligonucleotide end-products.


name: regulation of transcription-coupled nucleotide-excision repair

description: Any process that modulates the frequency, rate, or extent of the nucleotide-excision repair process that carries out preferential repair of DNA lesions on the actively transcribed strand of the DNA duplex. In addition, the transcription-coupled nucleotide-excision repair pathway is required for the recognition and repair of a small subset of lesions that are not recognized by the global genome nucleotide excision repair pathway.


name: cholesterol biosynthetic process via 24,25-dihydrolanosterol

description: The chemical reactions and pathways resulting in the formation of cholesterol, cholest-5-en-3 beta-ol, via the intermediate 24,25-dihydrolanosterol.


proline racemase activity

description: Catalysis of the reaction: L-proline = D-proline.


name: modulation by symbiont of host protein localization to phagocytic vesicle

description: Any process in which an organism modulates the frequency, rate or extent of protein localisation to the host phagosome. The host is defined as the larger of the organisms involved in a symbiotic interaction.


name: Ann Arbor Stage I Lymphocyte-Depleted Classic Hodgkin Lymphoma

description: Ann Arbor Classification: Stage I: Involvement of a single lymph node region (I); or localized involvement of a single extralymphatic organ or site in the absence of any lymph node involvement (IE) (rare in Hodgkin lymphoma).


name: Ann Arbor Stage I Supradiaphragmatic Lymphocyte-Depleted Classic Hodgkin Lymphoma


name: Ann Arbor Stage I Subdiaphragmatic Lymphocyte-Depleted Classic Hodgkin Lymphoma


Diaper candidiasis

description: An inflammatory skin condition in the diaper area superimposed with Candida infection, characterized by a bright red rash with a sharply demarcated edge and satellite lesions. Skin folds are often involved.


cellular hypotonic salinity response

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.


hypotonic salinity response

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.


mutator focus

description: A type of punctate focus localized to the perinuclear region of germline cytoplasm in C. elegans. Mutator foci are required for RNA interference (RNAi) and serve as sites of small inhibitory RNA (siRNA) amplification. As such, proteins that localize to mutator foci include RNA-directed RNA polymerases (RdRPs) and beta-nucleotidyltransferases. Mutator foci are distinct from, but adjacent to or partially overlap, P granules.


name: Stage IB Adult Soft Tissue Sarcoma AJCC v7


description: Catalysis of the reaction: 6-hydroxynicotinate + H2O + O2 = 2,6-dihydroxynicotinate + H2O2.


name: negative regulation of type IIa hypersensitivity

description: Any process that stops, prevents, or reduces the rate of type IIa hypersensitivity, a type of inflammatory response.


name: negative regulation of tolerance induction to nonself antigen

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of tolerance induction to nonself antigen.


regulation of type III hypersensitivity

description: Any process that modulates the frequency, rate, or extent of type III hypersensitivity, a type of inflammatory response.


name: negative regulation of tolerance induction dependent upon immune response

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of tolerance induction dependent upon immune response.


name: positive regulation of T cell antigen processing and presentation

description: Any process that activates or increases the frequency, rate, or extent of T cell antigen processing and presentation.


name: positive regulation of complement activation, classical pathway

description: Any process that activates or increases the frequency, rate or extent of complement activation by the classical pathway.


name: regulation of antibody-dependent cellular cytotoxicity

description: Any process that modulates the frequency, rate, or extent of antibody-dependent cellular cytotoxicity.


name: negative regulation of B cell antigen processing and presentation

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell antigen processing and presentation.


name: regulation of tolerance induction to nonself antigen

description: Any process that modulates the frequency, rate, or extent of tolerance induction to nonself antigen.


name: positive regulation of B cell antigen processing and presentation

description: Any process that activates or increases the frequency, rate, or extent of B cell antigen processing and presentation.


name: negative regulation of type IIb hypersensitivity

description: Any process that stops, prevents, or reduces the rate of type IIb hypersensitivity, a type of inflammatory response.


name: regulation of tolerance induction dependent upon immune response

description: Any process that modulates the frequency, rate, or extent of tolerance induction dependent upon immune response.


name: negative regulation of T-helper 17 cell lineage commitment

description: Any process that stops, prevents or reduces the frequency, rate or extent of T-helper 17 cell lineage commitment.


name: helper T cell enhancement of B cell mediated immune response

description: Positive regulation of a B cell mediated immune response mediated via cytokine production by a helper T cell.


name: positive regulation of type IIb hypersensitivity

description: Any process that activates or increases the frequency, rate or extent of type IIb hypersensitivity, a type of inflammatory response.


name: regulation of B cell antigen processing and presentation

description: Any process that modulates the frequency, rate, or extent of B cell antigen processing and presentation.


name: negative regulation of type II hypersensitivity

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of type II hypersensitivity.


name: negative regulation of T cell antigen processing and presentation

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell antigen processing and presentation.


name: positive regulation of peripheral tolerance induction

description: Any process that activates or increases the frequency, rate, or extent of peripheral tolerance induction.


name: positive regulation of tolerance induction to nonself antigen

description: Any process that activates or increases the frequency, rate, or extent of tolerance induction to nonself antigen.


name: helper T cell enhancement of T cell mediated immune response

description: Positive regulation of a T cell mediated immune response mediated via cytokine production by a helper T cell.


name: negative regulation of antibody-dependent cellular cytotoxicity

description: Any process that stops, prevents, or reduces the rate of antibody-dependent cellular cytotoxicity.


name: regulation of peripheral tolerance induction

description: Any process that modulates the frequency, rate, or extent of peripheral tolerance induction.


name: positive regulation of tolerance induction dependent upon immune response

description: Any process that activates or increases the frequency, rate, or extent of tolerance induction dependent upon immune response.


name: negative regulation of type III hypersensitivity

description: Any process that stops, prevents, or reduces the rate of type III hypersensitivity, a type of inflammatory response.


name: negative regulation of type I hypersensitivity

description: Any process that stops, prevents, or reduces the rate of type I hypersensitivity, a type of inflammatory response.


regulation of type IIb hypersensitivity

description: Any process that modulates the frequency, rate, or extent of type IIb hypersensitivity, a type of inflammatory response.


name: positive regulation of type IV hypersensitivity

description: Any process that activates or increases the frequency, rate or extent of type IV hypersensitivity, a type of inflammatory response.


name: positive regulation of type III hypersensitivity

description: Any process that activates or increases the frequency, rate or extent of type III hypersensitivity, a type of inflammatory response.


name: negative regulation of peripheral tolerance induction

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of peripheral tolerance induction.


sialic acid:proton symporter activity

description: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sialate(out) + H+(out) = sialate(in) + H+(in).