pancreatic bud formation

description: The morphogenetic process in which the foregut region specified to become the pancreas forms a bud.


UUC codon-amino acid adaptor activity

category: biolink:MolecularActivity biolink:Occurrent biolink:OntologyClass biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: A triplet codon-amino acid adaptor activity that recognizes a UUC codon.


tetracycline metabolic process

category: biolink:BiologicalProcess biolink:Occurrent biolink:OntologyClass biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: The chemical reactions and pathways involving tetracycline, (4S,4aS,5aS,6S,12aS)-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide, a broad-spectrum antibiotic produced by streptomyces bacteria that blocks binding of aminoacyl tRNA to the ribosomes of both Gram-positive and Gram-negative organisms (and those of organelles).


name: oxidoreductase activity, acting on the CH-OH group of donors, cytochrome as acceptor

description: Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces a cytochrome molecule.


D-iditol 2-dehydrogenase activity

description: Catalysis of the reaction: D-iditol + NAD+ = D-sorbose + NADH.


name: negative regulation of epinephrine uptake

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of epinephrine into a cell.


description: Any process in which an organism changes its pigmentation (lightening in response to a brighter environment or darkening in response to a dimmer environment) in response to a change in light intensity detected by light sensitive cells in the integument.


L-iduronidase activity

description: Catalysis of the hydrolysis of alpha-L-iduronosidic linkages in dermatan sulfate.


dormancy entry of symbiont in host

description: Entry into a dormant state of the symbiont within the host organism.


name: ABC-type thiosulfate transporter activity

description: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + thiosulfate(out) = ADP + phosphate + thiosulfate(in).


name: regulation of imaginal disc-derived wing size

description: Any process that modulates the size of an imaginal disc-derived wing.


description: Catalysis of the reaction: cis-3,4-phenanthrenedihydrodiol-4-carboxylate = 3,4-dihydroxyphenanthrene + H+ + 2 e- + CO2.


name: UDP-D-glucose:cyanidin 3-(p-coumaroyl)-glucoside 5-O-glucosyltransferase activity

description: Catalysis of the reaction: UDP-alpha-D-glucose + cyanidin 3-(p-coumaroyl)-glucoside = shisonin + UDP + H+.


name: protein localization to postsynaptic membrane

description: A process in which a protein is transported to, or maintained in, a location within a postsynaptic membrane.


acyl-CoA dehydrogenase (NADP+) activity

description: Catalysis of the reaction: acyl-CoA + NADP+ = 2,3-dehydroacyl-CoA + NADPH + H+.


name: tetrachloro-p-hydroquinone reductive dehalogenase activity

description: Catalysis of the reaction: 2,3,5,6-tetrachlorohydroquinone + 2 glutathione = 2,3,6-trichlorohydroquinone + glutathione disulfide + HCl.


name: spermidine:feruloyl CoA N-acyltransferase activity

description: Catalysis of the transfer of a feruloyl group to a nitrogen atom on the spermidine molecule.


siderophore metabolic process

description: The chemical reactions and pathways involving siderophores, low molecular weight Fe(III)-chelating substances made by aerobic or facultatively anaerobic bacteria, especially when growing under iron deficient conditions. The complexes of Fe(3+)-siderophores have very high stability constants and are taken up by specific transport systems by microorganisms; the subsequent release of iron requires enzymatic action.


name: chemorepulsion of branchiomotor neuron axon in branchial arch mesenchyme

description: The process in which a branchiomotor neuron growth cone in the branchial arch mesenchyme is directed to a specific target site in the branchial arch mesenchyme in response to a repulsive chemical cue. Branchiomotor neurons are located in the hindbrain and innervate branchial arch-derived muscles that control jaw movements, facial expression, the larynx, and the pharynx.


purine alkaloid metabolic process

description: The chemical reactions and pathways involving purine alkaloids, compounds derived from purine and composed of an N-containing double ring structure.


name: dopamine biosynthetic process from tyrosine

description: The chemical reactions and pathways resulting in the formation of dopamine (3,4-dihydroxyphenylethylamine) from L-tyrosine, via the metabolic precursor 3,4-dihydroxy-L-phenylalanine (L-dopa). Dopamine is a catecholamine neurotransmitter and a metabolic precursor of norepinephrine and epinephrine.


description: The chemical reactions and pathways resulting in the formation of 5,6,7,8-tetrahydrosarcinapterin.


peptidyl-lysine carboxylation

description: The modification of peptidyl-lysine to form peptidyl-N6-carboxy-L-lysine.


phosphoarginine metabolic process

description: The chemical reactions and pathways involving phosphoarginine, a phosphagen of L-arginine with phosphoric acid containing the phosphoamide bond. It is a source of energy in the contraction of muscle in invertebrates, corresponding to phosphocreatine in the muscles of vertebrates.


cellular response to tellurium ion

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tellurium ion stimulus.


name: epithelial cell differentiation involved in mammary gland bud morphogenesis

description: The process in which a cell of the mammary placode becomes a cell of the mammary gland bud.


positive regulation of flocculation

description: Any process that activates or increases the frequency, rate or extent of flocculation.


name: galactosamine transmembrane transporter activity

description: Enables the transfer of galactosamine from one side of a membrane to the other. Galactosamine is an aminodeoxysugar; D-galactosamine is a constituent of some glycolipids and glycosaminoglycans, commonly as its N-acetyl derivative.


negative regulation of leaf development

description: Any process that stops, prevents or reduces the frequency, rate or extent of leaf development.


name: cyanidin 3-O-glucoside 5-O-glucosyltransferase (acyl-glucose dependent) activity

description: Catalysis of the reaction: cyanidin 3-O-beta-D-glucoside betaine + 1-O-feruloyl-beta-D-glucose = cyanin betaine + ferulate + H+.


lateral root branching

description: Any process involved in the formation of branches in lateral roots.


renal water retention

description: The process in which renal water excretion is decreased.


pronephric nephron tubule morphogenesis

description: The process in which the anatomical structures of a pronephric nephron tubule are generated and organized from an epithelium. A pronephric nephron tubule is an epithelial tube that is part of the pronephric nephron.


nopaline metabolic process

description: The chemical reactions and pathways involving nopaline, (N-(I-carboxy-4-guanidinobutyl)glutamic acid), a rare amino-acid derivative.


thioglucosidase activity

description: Catalysis of the reaction: a thioglucoside + H2O = a thiol + a sugar.


chlorate reductase activity

description: Catalysis of the reaction: AH(2) + chlorate = A + chlorite + H2O + H+.


coumarin 7-hydroxylase activity

description: Catalysis of the reaction: coumarin + O2 + NADPH + H+ = hydroxycoumarin + H2O + NADP+.


name: G protein-coupled folate receptor activity

description: Combining with folate and transmitting the signal from one side of the membrane to the other by activating an associated G-protein, initiating a change in cell activity.


cellular response to acadesine

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acadesine stimulus.


name: anterior midgut (ectodermal) morphogenesis

description: The process in which the anatomical structures of the anterior midgut (ectodermal) are generated and organized.


response to diphenidol

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diphenidol stimulus.


description: Catalysis of the reaction: acetyl phosphate + peptidyl-L-lysine = phosphate + peptidyl-N6-acetyl-L-lysine.


name: endocardial cushion cell fate specification

description: The process involved in the specification of endocardial cushion cell identity. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment.


homeostatic process

description: Any biological process involved in the maintenance of an internal steady state.


name: cellular response to trehalose-6-phosphate stimulus

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a trehalose-6-phosphate stimulus.


name: negative regulation of dendritic cell antigen processing and presentation

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of dendritic cell antigen processing and presentation.


name: positive regulation of dopamine biosynthetic process

description: Any process that activates or increases the frequency, rate or extent of dopamine biosynthetic process.


sinus venosus formation

description: The developmental process pertaining to the initial formation of the sinus venosus from unspecified parts. The sinus venosus is a heart chamber attached to the atrium on the venous side of the embryonic heart.


pole cell formation

description: Formation of a small group of cells (pole cells) at the posterior pole of the insect blastula. They are the first cells to cellularize after the arrival of nuclei at the end of the syncytial blastula stage and are the precursors to the insect germ cells.


name: maintenance of protein localization at growing cell tip

description: Any process in which localization of a protein is maintained at the growing cell tip.


name: linear malto-oligosaccharide phosphorylase activity

description: Catalysis of the reaction: hydrogenphosphate + a linear malto-oligosaccharide = alpha-D-glucose 1-phosphate + a linear malto-oligosaccharide.


homoserine dehydrogenase activity

description: Catalysis of the reaction: L-homoserine + NADP+ = L-aspartate-4-semialdehyde + NADPH + H+.


URM1 ligase activity

description: Catalysis of the transfer of URM1 to a substrate protein via the reaction X-URM1 + S = X + S-URM1, where X is either an E2 or E3 enzyme, the X-URM1 linkage is a thioester bond, and the S-URM1 linkage is an isopeptide bond between the C-terminal amino acid of URM1 and the epsilon-amino group of lysine residues in the substrate.


name: negative regulation of uterine smooth muscle relaxation

description: Any process that stops, prevents or reduces the frequency, rate or extent of uterine smooth muscle relaxation.


name: pentaerythritol trinitrate reductase activity

description: Catalysis of the reaction: pentaerythritol trinitrate + NADPH = NADP+ + nitrate + pentaerythritol dinitrate.


ribonuclease U2 activity

description: Catalysis of the two-stage endonucleolytic cleavage to nucleoside 3'-phosphates and 3'-phosphooligonucleotides ending in Ap or Gp with 2',3'-cyclic phosphate intermediates.


name: cell wall disassembly involved in floral organ abscission

description: A cellular process that results in the breakdown of the cell wall that contributes to the process of floral organ abscission.


description: Catalysis of the reaction: epsilon-(L-gamma-glutamyl)-L-lysine = L-lysine + 5-oxo-L-proline.


cyclodextrin binding

description: Binding to cyclodextrin.


description: Catalysis of the reaction: phosphate + oxaloacetate = phosphoenolpyruvate + HCO3-.


description: Catalysis of the reaction: 2,3-dihydroxyethylbenzene + O2 = H+ + 2-hydroxy-6-oxoocta-2,4-dienoate.


name: maintenance of granzyme B location in T cell secretory granule

description: A process in which the protease granyme B is maintained in a secretory granule in a T cell and prevented from moving elsewhere.


name: oxidised low-density lipoprotein particle receptor activity

description: Combining with an oxidised low-density lipoprotein particle and delivering the oxidised low-density lipoprotein particle into the cell via endocytosis.


N-acylsphingosine galactosyltransferase

description: Catalysis of the reaction: N-acylsphing-4-enine + UDP-alpha-D-galactose = a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + H+ + UDP.


description: Catalysis of the reaction 2-dehydro-3-deoxy-L-rhamnonate = pyruvate + (S)-lactaldehyde.


sympathetic neuron axon guidance

description: The chemotaxis process that directs the migration of a sympathetic neuron axon growth cone to a specific target site in response to a combination of attractive and repulsive cues.


tensidol A biosynthetic process

description: The chemical reactions and pathways resulting in the formation of tensidol A.


description: Catalysis of the reaction: GlcNAc-1,6-anhMurNAc-L-Ala-gamma-D-Glu-DAP-D-Ala + H2O glcNAc-1,6-anhMurNAc + L-Ala-gamma-D-Glu-DAP-D-Ala.


extensin metabolic process

description: The chemical reactions and pathways involving extensins, a group of 60-90 kDNA hydroxyproline (Hyp)-rich glycoproteins whose polypeptide backbone consists of many repeats of structural Ser(Hyp)4-6 motifs, with heavily glycosylated 1-4 arabinose residues O-linked to contiguous stretches of Hyp residues, with most of the Ser residues being O-galactosylated.


description: The chemical reactions and pathways involving 17-methylnonadec-1-ene.


name: rebaudioside B glucosyltransferase activity

description: Catalysis of the reaction: rebaudioside B + UDP-alpha-D-glucose = rebaudioside A + UDP + H+.


cellular response to cytochalasin B

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytochalasin B stimulus.


name: adhesion of symbiont to host epithelial cell

description: The attachment of a symbiont to a host epithelial cell via adhesion molecules, general stickiness etc., either directly or indirectly.


name: mechanoreceptor differentiation involved in mechanosensory epithelium regeneration

description: Differentiation of new mechanoreceptors to replace those lost or destroyed by injury.


name: GPI anchor biosynthetic process via N-glycyl-glycosylphosphatidylinositolethanolamine

description: The chemical reactions and pathways resulting in the formation of a C-terminal peptidyl-glycine ethanolamide-linked glycosylphosphatidylinositol (GPI) anchor following hydrolysis of a glycyl-peptide bond in the carboxy-terminal region of a membrane-associated protein.


protein-serine epimerase activity

description: Catalysis of the reaction: (protein)-L-serine = (protein)-D-serine.


intracellular histidine homeostasis

description: A homeostatic process involved in the maintenance of a steady state level of histidine within a cell.


description: Catalysis of the transfer of N-acetylglucosamine (GlcNAc) in a beta-1,3 linkage to the mannose(beta-1,4)Glc disaccharide core of glycolipids.


name: maintenance of imaginal disc-derived wing hair orientation

description: Ensuring that hairs in the imaginal disc-derived wing continue to point distally during development, following the initial establishment of wing hair polarity.


description: Catalysis of the reaction: 3-hydroxy-2-methylhexanoyl-CoA = 2-methyl-3-oxohexanoyl-CoA + 2 H+ + 2 e-.


name: IAA-amino acid conjugate hydrolase activity

description: Catalysis of the cleavage of the amide bond between IAA (auxin) and the conjugated amino acid.


description: Catalysis of the reaction (4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione = 3-hydroxy-5-phosphonooxypentane-2,4-dione.


description: Catalysis of the reaction: H2O + N(6)-glutaryl-L-lysyl-[protein] + NAD+ = 2''-O-glutaryl-ADP-D-ribose + L-lysyl-[protein] + nicotinamide.


nucleotide binding

description: Binding to a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose or deoxyribose.


name: vanadium incorporation into metallo-sulfur cluster

description: The incorporation of vanadium a metallo-sulfur cluster such as VFe(7-8)S(n).


uracil binding

description: Binding to uracil.


cytosine binding

description: Binding to cytosine.


name: all-trans retinal 3,4-desaturase activity

description: Catalysis of the reaction: all-trans-retinal + 2 H+ + O2 + 2 reduced [adrenodoxin] = all-trans-3,4-didehydro retinal + 2 H2O + 2 oxidized [adrenodoxin].


name: maturation of 5S rRNA from tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

description: Any process involved in the maturation of a precursor 5S ribosomal RNA (rRNA) molecule into a mature 5S rRNA molecule from the pre-rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 4.5S rRNA, and the 5S rRNA in that order from 5' to 3' along the primary transcript.


glutathione synthase activity

description: Catalysis of the reaction: L-gamma-glutamyl-L-cysteine + ATP + glycine = ADP + glutathione + 2 H+ + phosphate.


description: The chemical reactions and pathways involving (+)-epi-alpha-bisabolol.


description: The methylation of the N-terminal tyrosine of proteins to form the derivative N-methyl-L-tyrosine.


name: positive regulation of cell communication by electrical coupling involved in cardiac conduction

description: Any process that activates or increases the frequency, rate or extent of cell communication by electrical coupling involved in cardiac conduction.


dUTP catabolic process

description: The chemical reactions and pathways resulting in the breakdown of dUTP, deoxyuridine (5'-)triphosphate.


name: negative regulation of axial mesodermal cell fate specification

description: Any process that stops, prevents, or reduces the frequency, rate or extent of axial mesoderm cell fate specification.


DNA recombinase disassembly

description: The disaggregation of a DNA recombinase complex into its constituent strand exchange proteins (recombinases).


mesonephric nephron development

description: The process whose specific outcome is the progression of a nephron in the mesonephros over time, from its formation to the mature structure. A nephron is the functional unit of the kidney.


chloroplast disassembly

description: The disaggregation of a chloroplast into its constituent components.


name: negative regulation of natural killer cell proliferation

description: Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer cell proliferation.


description: Catalysis of the reaction: (S)-lactate + oxaloacetate = malate + pyruvate.


description: Catalysis of the reaction: glucarolactone + sinapoyl-CoA = O-sinapoylglucarolactone + CoA.


name: N-alpha,N-alpha,N-alpha-trimethyl-L-histidine biosynthesis from histidine

description: The pathway resulting in the formation of N-alpha,N-alpha,N-alpha-trimethyl-L-histidine from histidine. Histidine undergoes three methylations by a histidine-alpha-N-methyltransferase (EC:2.1.1.44) to form N-alpha,N-alpha,N-alpha-trimethyl-L-histidine (also known as hercynine or histidine betaine).


description: Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + quercetin 3-sulfate = adenosine 3',5'-diphosphate + H+ + quercetin 3,3'-disulfate.


description: Catalysis of the reaction: L-serine + CDP-ethanolamine = L-serine-phosphoethanolamine + CMP + H+.


thromboxane A2 receptor activity

description: Combining with thromboxane A2 (TXA(2)) and transmitting the signal across the membrane to activate an associated G-protein.


description: Catalysis of the reaction: feruloyl-CoA + galactarate = 2-(E)-O-feruloyl-D-galactarate + CoA.


perianth development

description: The process whose specific outcome is the progression of the perianth over time, from its formation to the mature structure. The perianth is a collective phyllome structure composed of two or more petals, sepals, or tepals.


prechordal plate formation

description: The formation of the prechordal plate. The prechordal plate is a thickening of the endoderm at the cranial end of the primitive streak formed by the involution of Spemann's organizer cells. The prechordal plate and the notochord induce the formation of the neural plate from the overlying ectodermal cells.


name: eriodictyol dibenzoylmethane tautomer 6C-glucosyltransferase activity

description: Catalysis of the reaction: eriodictyol dibenzoylmethane tautomer + UDP-alpha-D-glucose = 6C-beta-D-glucosyl-2-hydroxyeriodictyol + UDP + H+.


delta24-sterol reductase activity

description: Catalysis of the reaction: NADP+ + 5-alpha-cholest-7-en-3-beta-ol = NADPH + H+ + 5-alpha-cholesta-7,24-dien-3-beta-ol.


description: Catalysis of the reaction: 2,6-dichlorohydroquinone + O2 + H2O = HCl + 2 H+ + 2-chloromaleylacetate.


reductive pentose-phosphate cycle

description: The fixation of carbon dioxide (CO2) as glucose in the chloroplasts of C3 plants; uses ATP and NADPH formed in the light reactions of photosynthesis; carbon dioxide reacts with ribulose 1,5-bisphosphate (catalyzed by the function of ribulose-bisphosphate carboxylase) to yield two molecules of 3-phosphoglycerate; these are then phosphorylated by ATP to 1,3-bisphosphateglyceraldehyde which, in turn, is then reduced by NADPH to glyceraldehyde 3-phosphate. The glyceraldehyde 3-phosphate is converted to fructose 5-phosphate and ribulose 5-phosphate by aldolase and other enzymes; the ribulose 5-phosphate is phosphorylated by ATP to ribulose 1,5-bisphosphate.


plant ovule development

description: The process whose specific outcome is the progression of the ovule over time, from its formation to the mature structure. The ovule is the structure in seed plants enclosing the female gametophyte, and is composed of the nucellus, one or two integuments, and the funiculus; it develops into the seed.


description: The chemical reactions and pathways resulting in the breakdown of (R)-4-hydroxymandelate, the anion of (R)-4-hydroxymandelic acid.


name: negative regulation of mesoderm formation

description: Any process that stops, prevents or reduces the frequency, rate or extent of mesoderm formation.


undecan-2-one metabolic process

description: The chemical reactions and pathways involving undecan-2-one.


name: positive regulation of epinephrine uptake

description: Any process that activates or increases the frequency, rate or extent of the directed movement of epinephrine into a cell.


description: Catalysis of the reaction: 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine + ATP = (2-amino-4-hydroxy-7,8-dihydropteridin-6-yl)methyl diphosphate + AMP + 2 H+.


name: vascular associated smooth muscle cell differentiation involved in phenotypic switching

description: Any vascular smooth muscle cell differentiation that is involved in phenotypic switching.


chlorophyllide metabolic process

description: The chemical reactions and pathways involving chlorophyllides, any chlorophyll lacking the terpenoid side chain such as phytyl or farnesyl.


description: Catalysis of the reaction: quercetin-7-olate + UDP-L-rhamnose = H+ + quercetin 3-O-rhamnoside + UDP.


name: negative regulation of toll-like receptor 10 signaling pathway

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 10 signaling pathway.


description: Catalysis of the reaction: pyridoxine + UDP-D-glucose = 5'-O-beta-D-glucosylpyridoxine + H+ + UDP.


name: protocatechuate catabolic process, meta-cleavage

description: The chemical reactions and pathways resulting in the breakdown of protocatechuate, the anion of 3,4-dihydroxybenzoic acid, to yield oxaloacetate and pyruvate.


aspartate dehydrogenase activity

description: Catalysis of the reaction: L-aspartate + H2O + NAD(P)+ = oxaloacetate + NH3 + NAD(P)H + H+.


name: fluconazole transmembrane transporter activity

description: Enables the transfer of fluconazole from one side of a membrane to the other. Fluconazole is an antifungal drug used for oral candidiasis and cryptococcal meningitis; it is still under study for treatment of vaginal candidiasis and other fungal infections.


name: nickel cation transmembrane transporter activity

description: Enables the transfer of nickel (Ni) cations from one side of a membrane to the other.


name: germacrene A acid 8beta-hydroxylase activity

description: Catalysis of the reaction: germacra-1(10),4,11(13)-trien-12-oate + NADPH + O2 + H+ = 8beta-hydroxy-germacra-1(10),4,11(13)-trien-12-oate + NADP + H2O.


name: positive regulation of placenta blood vessel development

description: Any process that activates or increases the frequency, rate or extent of placenta blood vessel development.


name: positive regulation of kainate selective glutamate receptor signaling pathway

description: Any process that activates or increases the frequency, rate or extent of the kainate selective glutamate receptor signaling pathway.


D-threo-aldose 1-dehydrogenase activity

description: Catalysis of the reaction: a D-threo-aldose + NAD+ = a D-threo-aldono-1,5-lactone + NADH.


name: positive regulation of cell migration by VEGF-activated platelet derived growth factor receptor signaling pathway

category: biolink:Pathway biolink:OntologyClass biolink:BiologicalProcess biolink:Occurrent biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: The series of molecular signals initiated by vascular endothelial growth factor (VEGF) binding to a platelet-derived growth factor receptor (PDGFR) on the surface of a cell, which activates or increases the frequency, rate or extent of the orderly movement of a cell from one site to another.


name: regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator

description: Any process that modulates the frequency, rate or extent of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator.


succinyl-CoA catabolic process

description: The chemical reactions and pathways resulting in the breakdown of succinyl-CoA.


name: cerebellar granule cell precursor tangential migration

description: The early migration of granule cell precursors in which cells move orthogonal to the direction of radial migration and ultimately cover the superficial zone of the cerebellar primordium.


name: femoral head articular cartilage development

description: The process whose specific outcome is the progression of femoral head articular cartilage over time, from its formation to the mature structure.


description: Catalysis of the reaction: alpha-D-glucose 1-phosphate + ATP = ADP-glucose + diphosphate.


description: Catalysis of the transfer of an L-fucosyl group from GDP-beta-L-fucose to an acceptor molecule to form an alpha-(1->6) linkage.


tRNA nucleotidyltransferase activity

description: Catalysis of the reaction: tRNA(n+1) + phosphate = tRNA(n) + a nucleoside diphosphate.


phosphatidylserine catabolic process

description: The chemical reactions and pathways resulting in the breakdown of phosphatidylserines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of L-serine.


crotonyl-CoA hydratase activity

description: Catalysis of the reaction: Acetyl-CoA + [protein]-L-lysine = CoA + [protein]-N(6)-acetyl-L-lysine.


description: Catalysis of the reaction: H+ + 2-methylpropionitrile + O2 + NADPH = 2-hydroxy-2-methylpropanenitrile + NADP + H2O.


name: regulation of plasma membrane sterol distribution

description: Any process that modulates the proportions or spatial arrangement of sterols in the plasma membrane.


name: DNA synthesis involved in DNA replication

description: Synthesis of DNA that is a part of the process of duplicating one or more molecules of DNA.


name: 3,3',5,5'-tetrabromobisphenol A reductive dehalogenase activity

description: Catalysis of the reaction: 3,3',5,5'-tetrabromobisphenol A + 2 H+ + 2 e- = 3,3',5-tribromobisphenol A + HBr.


description: Catalysis of the reaction: 3-(N-formyl)-formiminopyruvate + H2O = 3-formiminopyruvate + formate.


name: pole plasm mitochondrial srRNA localization

description: Any process in which mitochondrial small ribosomal RNA is transported to, or maintained in, the oocyte pole plasm. An example of this is found in Drosophila melanogaster.


name: central nervous system interneuron axonogenesis

description: Generation of a long process that carries efferent (outgoing) action potentials from the cell body towards target cells from a neuron located in the central nervous system whose axons remain within a single brain region.


name: monoatomic anion:sodium symporter activity

description: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: monoatomic anion(out) + Na+(out) = monoatomic anion(in) + Na+(in).


name: epithelial to mesenchymal transition involved in cardiac fibroblast development

description: A transition where an epicardial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell that will mature into a cardiac fibroblast.


name: all-trans-nonaprenyl-diphosphate synthase (geranyl-diphosphate specific) activity

description: Catalysis of the reaction: geranyl diphosphate + 7 isopentenyl diphosphate = 7 diphosphate + all-trans-nonaprenyl diphosphate.


name: intracellularly phosphatidylinositol-3,5-bisphosphate-gated monatomic cation channel activity

description: Enables the transmembrane transfer of cations by a channel that opens when phosphatidylinositol-3,5-bisphosphate has been bound by the channel complex or one of its constituent parts.


8-oxo-GDP phosphatase activity

description: Catalysis of the reaction 8-oxo-GDP + H2O = 8-oxo-GMP + phosphate.


endothelial cell-matrix adhesion

description: The binding of an endothelial cell to the extracellular matrix via adhesion molecules.


name: negative regulation of cardiac conduction

description: Any process that stops, prevents or reduces the frequency, rate or extent of cardiac conduction.


description: Catalysis of the reaction: 2-chlorobenzoate + NADH + H+ + O2 = catechol + chloride + NAD+ + CO2.


floral whorl formation

description: The process that gives rise to the floral whorl. This process pertains to the initial formation of a structure from unspecified parts.


name: proteinogenic amino acid catabolic process

description: The chemical reactions and pathways resulting in the breakdown of any amino acid that is incorporated into protein naturally by ribosomal translation of mRNA, and that has a specific codon for translation from mRNA to protein.


description: The phosphorylation of a peptidyl-threonine to form peptidyl-O-phospho-L-threonine on an identical protein. For example, phosphorylation by the other kinase within a homodimer.


name: regulation of asexual sporulation resulting in formation of a cellular spore

description: Any process that modulates the frequency, rate or extent of the formation of a cellular spore derived from the products of mitosis.


description: The chemical reactions and pathways resulting in the formation of any one of a family of organic molecules consisting of a purine or pyrimidine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside).


name: protein localization to cortical endoplasmic reticulum

description: A process in which a protein is transported to, or maintained in, a location within a cortical endoplasmic reticulum.


glycine dehydrogenase activity

description: Catalysis of the reaction: glycine + H2O + NAD+ = glyoxylate + NH3 + NADH.


name: positive regulation of metula development

description: Any process that activates or increases the frequency, rate or extent of metula development, a process that leads to the formation of metulae. Metulae are elongated mononucleate cells that bud from the surface of the conidiophore tip.


name: negative regulation of invasive growth in response to glucose limitation

description: Any process that stops, prevents, or reduces the frequency, rate or extent of invasive growth in response to glucose limitation.


name: positive regulation of single strand break repair

description: Any process that activates or increases the frequency, rate or extent of single strand break repair.


ITPase activity

description: Catalysis of the reaction: ITP + H2O = IDP + H+ + phosphate.


renal phosphate ion absorption

description: A renal system process in which phosphate ions are taken up from the collecting ducts and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures.


description: Catalysis of the reaction: 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + L-alanyl-tRNA(Ala) = 1,2-diacyl-sn-glycero-3-phospho-1'-(3'-O-L-alanyl)-sn-glycerol + tRNA(Ala).


name: photosynthetic electron transport in photosystem I

description: A photosynthetic electron transport chain in which electrons move from the primary electron acceptor (Quinone, X) through a chain of electron transport molecules in the thylakoid membrane until they reach ferredoxin which passes the electron to the ultimate electron acceptor; NADP.


galactomannan biosynthetic process

description: The chemical reactions and pathways resulting in the formation of galactomannan, a polysaccharide composed of D-galactosyl and D-mannosyl. The mannosyl units form the backbone structure (a linear main chain) with the D-galactosyl as single side units.


name: regulation of innate immunity memory response

description: Any process that modulates the frequency, rate or extent of innate immunity memory response.


mesenchymal cell fate commitment

description: The process in which a cell becomes committed to become a mesenchymal cell.


cysteine-type aminopeptidase activity

description: Catalysis of the hydrolysis of a single N-terminal amino acid residue from a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile.


histone deubiquitinase activity

description: A deubiquitinase that cleaves ubiquitin from a histone protein to which it is conjugated.


emericellin catabolic process

description: The chemical reactions and pathways resulting in the breakdown of emericellin.


description: The process of immune complex clearance by erythrocytes. The process often starts with binding of complement receptor 1 (CR1) on the surface of erythrocytes to a complement coated immune complex. The complex bound to erythrocyte CR1 is then transported to the liver or spleen where it is presented to phagocytes. The process ends when the complex is removed from CR1, allowing the erythrocyte to return to general circulation.


3-chlorobenzoate-3,4-oxygenase activity

description: Catalysis of the reaction: 3-chlorobenzoate + O2 + a reduced electron acceptor = 3-chlorobenzoate-cis-3,4-diol + an oxidized electron acceptor.


name: high-affinity glutamine transmembrane transporter activity

description: Enables the transfer of glutamine from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.


name: anther wall tapetum cell differentiation

description: The process in which a relatively unspecialized cell acquires specialized features of an anther cell wall tapetum cell. The tapetum is a layer of cells that provides a source of nutrition for the pollen grains as they mature.


name: glucose catabolic process to lactate via pyruvate

description: The anaerobic enzymatic chemical reactions and pathways resulting in the breakdown of glucose to lactate, via canonical glycolysis, yielding energy in the form of adenosine triphosphate (ATP).


description: Catalysis of the reaction: GDP-alpha-D-mannose + queuosine34 in tRNA(Asp) = GDP + H+ + O-4''-alpha-D-mannosylqueuosine34 in tRNA(Asp).


name: homophytochelatin synthase activity (polymer-forming)

description: Catalysis of the reaction: glutathionate + a poly gamma-glutamylcysteine-beta-alanine = glycine + a poly gamma-glutamylcysteine-beta-alanine.


ABC-type bile acid transporter activity

description: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: bile acid(in) + ATP + H2O -> bile acid(out) + ADP + phosphate.


cellular response to nitrogen dioxide

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrogen dioxide (NO2) stimulus.


leaf formation

description: The process that gives rise to a leaf. This process pertains to the initial formation of a structure from unspecified parts.


description: Catalysis of the reaction: (3S)-3-hydroxy-L-aspartate = NH4 + oxaloacetate.


chlorite O2-lyase activity

description: Catalysis of the reaction: chloride + O2 = chlorite.


formylaspartate deformylase activity

description: Catalysis of the reaction: N-formyl-L-aspartate + H2O = formate + L-aspartate.


name: mesonephric glomerular mesangial cell differentiation

description: The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the glomerular mesangial cells of the mesonephros as it progresses from its formation to the mature state.


name: 4-hydroxy-3-methylbut-2-enyl-diphosphate synthase activity (flavodoxin)

description: Catalysis of the reaction: (2E)-4-hydroxy-3-methylbut-2-enyl diphosphate + 2 H+ + H2O + oxidized [flavodoxin] = 2-C-methyl-D-erythritol 2,4-cyclic diphosphate + reduced [flavodoxin].


description: Catalysis of the reaction: L-tyrosyl-[protein] + NAD+ = H+ + nicotinamide + O-(ADP-D-ribosyl)-L-tyrosyl-[protein].


maintenance of viral latency

description: The perpetuation of a latent state, generally by repressing the viruses own lytic genes expression and ensuring expression of viral genes which function to keep the viral genome from being detected by the host defense mechanisms.


name: modulation by symbiont of defense-related host calcium ion flux

description: Any process in which an organism modulates the frequency, rate or extent of calcium ion fluxes as part of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.


name: cellular modified histidine catabolic process

description: The chemical reactions and pathways resulting in the breakdown of compounds derived from histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid.


oogonium stage

description: The stage in mammalian oogenesis when the primordial germ cell is hardly distinguishable from other cortical cells of the ovary.


description: Catalysis of the reaction: Cypridina luciferin + O2 = oxidized Cypridina luciferin + CO2 + light.


name: negative regulation of extraocular skeletal muscle development

description: Any process that stops, prevents, or reduces the frequency, rate or extent of extraocular skeletal muscle development. Extraocular skeletal muscle development is the process whose specific outcome is the progression of the extraocular skeletal muscle over time, from its formation to the mature structure. The extraocular muscle is derived from cranial mesoderm and controls eye movements. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle.


benzonitrile metabolic process

description: The chemical reactions and pathways involving benzonitrile. Benzonitrile is used as a solvent and chemical intermediate in the pharmaceutical, dyestuffs and rubber industries. It is highly toxic and harmful in contact with skin.


beta-zeacarotene catabolic process

description: The chemical reactions and pathways resulting in the breakdown of beta-zeacarotene.


P-type zinc transporter activity

description: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Zn2+(in) = ADP + phosphate + Zn2+(out).


phenylethylamine metabolic process

description: The chemical reactions and pathways involving phenylethylamine, an amine with pharmacological properties similar to those of amphetamine, occurs naturally as a neurotransmitter in the brain, and is present in chocolate and oil of bitter almonds.


positive regulation of sterol import

description: Any process that activates or increases the frequency, rate or extent of sterol import.


anterior midgut invagination

description: Internalization of the anterior midgut into the interior of the embryo.


response to Gram-positive bacterium

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a Gram-positive bacterium.


description: Catalysis of the reaction: cyclopropanecarboxyl-CoA = crotonoyl-CoA.


name: aromatic amino acid family catabolic process to alcohol via Ehrlich pathway

description: The chemical reactions and pathways involving the catabolism of aromatic amino acids to produce aromatic alcohols with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. When an aromatic family amino acid, phenylalanine, tyrosine, or tryptophan, is used as the substrate, 2-phenylethanol, 4-hydroxyphenylethanol, or tryptophol, respectively, is produced. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of alcohols, often collectively referred to as fusel alcohols. Depending on the redox state of the cells, carboxylic acid derivatives may be produced instead of alcohols.


pronephric nephron morphogenesis

description: The process in which the anatomical structures of the pronephric nephron are generated and organized. A pronephric nephron is the functional unit of the pronephros.


tRNA adenosine deamination to inosine

description: The removal of an amine group from an adenosine to produce inosine within a tRNA molecule.


name: glycogen cell differentiation involved in embryonic placenta development

description: The process in which a relatively unspecialized cell acquires specialized features of a glycogen cell of the placenta. A glycogen cell is a vacuolated glycogen-rich cell that appears in compact cell islets of the spongiotrophoblast layer.


name: regulation of gamma-delta T cell activation involved in immune response

description: Any process that modulates the frequency, rate or extent of gamma-delta T cell activation involved in immune response.


tyramine N-feruloyltransferase activity

description: Catalysis of the reaction: feruloyl-CoA + tyramine = CoA + N-feruloyltyramine.


succinyl-CoA pathway

description: The chemical reactions that utilize succinyl-CoA in the synthesis of protoporphyrin IX.


name: negative regulation of calcium channel activity in another organism

description: Any process in which an organism stops, prevents or reduces the frequency, rate or extent of the activity of a calcium channel in another organism.


name: thyrotropin-releasing hormone receptor activity

description: Combining with thyrotropin-releasing hormone to initiate a change in cell activity.


ground meristem histogenesis

description: The formation of the primary meristem or meristematic tissue that gives rise to the ground tissues.


lagging strand initiation

description: The process in which the synthesis of DNA from a template strand in a net 3' to 5' direction is started.


description: Catalysis of the reaction: keto-phenylpyruvate + L-aspartate = L-phenylalanine + oxaloacetate.


piperine biosynthetic process

description: The chemical reactions and pathways resulting in the formation of piperine.


sphingosine hydroxylase activity

description: Catalysis of the hydroxylation of sphingolipid long chain bases.


regulation of aorta morphogenesis

description: Any process that modulates the frequency, rate or extent of aorta morphogenesis.


description: Catalysis of the reaction: pyridoxamine 5'-phosphate + 2-oxoglutarate = pyridoxal 5'-phosphate + D-glutamate.


name: molybdenum incorporation via L-cysteinyl copper sulfido molybdopterin cytosine dinucleotide

description: The incorporation of molybdenum into a protein by L-cysteinyl copper sulfido molybdopterin cytosine dinucleotide.


amidinoaspartase activity

description: Catalysis of the reaction: N-amidino-L-aspartate + H2O = L-aspartate + urea.


gamma-delta T cell proliferation

description: The expansion of a gamma-delta T cell population by cell division.


pheromone biosynthetic process

description: The chemical reactions and pathways resulting in the formation of pheromones, a substance that is secreted and released by an organism and detected by a second organism of the same or a closely related species, in which it causes a specific reaction, such as a definite behavioral reaction or a developmental process.


glyoxylate reductase activity

description: Catalysis of the reaction: glycolate + NAD(P)+ = glyoxylate + NAD(P)H.


name: regulation of type IV site-specific deoxyribonuclease activity

description: Any process that modulates the frequency, rate or extent of a type IV restriction endodeoxyribonuclease activity.


description: Catalysis of the reaction: cyclohex-1-ene-1-carboxyl-CoA + H2O = 2-hydroxycyclohexane-1-carboxyl-CoA.


ATP-dependent protein folding chaperone

description: Binding to a protein or a protein-containing complex to assist the protein folding process, driven by ATP hydrolysis.


thiosulfate dehydrogenase activity

description: Catalysis of the reaction: 2 thiosulfate + 2 ferricytochrome c = tetrathionate + 2 ferrocytochrome c.


description: The acetylation of the N-terminal tyrosine of proteins to form the derivative N-acetyl-L-tyrosine.


name: glutathione-dependent sulfide quinone oxidoreductase activity

description: Catalysis of the reaction: a quinone + glutathione + H+ + hydrogen sulfide = a quinol + S-sulfanylglutathione.


negative regulation of locomotor rhythm

description: Any process that stops, prevents or reduces the frequency, rate or extent of locomotor rhythm.


name: complement component C1q receptor activity

description: Combining with the C1q complex, a component of the classical complement cascade, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


coronary sinus valve development

description: The progression of the valve of the coronary sinus over time, from its formation to the mature structure.


nematode pharyngeal muscle development

description: The process whose specific outcome is the progression of the nematode pharyngeal muscle over time, from its formation to the mature structure.


positive regulation of signaling

description: Any process that activates, maintains or increases the frequency, rate or extent of a signaling process.


name: central nervous system structural organization

description: The process that contributes to the act of creating the structural organization of the central nervous system structure. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain, spinal cord and spinal nerves. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord.


name: peptidyl-1-thioglycine biosynthetic process, internal

description: The chemical reactions and pathways resulting in the formation of internal peptidyl-1-thioglycine, which has an internal C=S bond, instead of an internal C=O bond, in the peptide.


establishment of left sidedness

description: The initial formation of the type asymmetry in an organism's body plan or part of an organism that established the pattern characteristic to its left side.


name: oxidoreductase activity, acting on CH or CH2 groups, oxygen as acceptor

description: Catalysis of an oxidation-reduction (redox) reaction in which a CH2 group acts as a hydrogen or electron donor and reduces an oxygen molecule.


name: efferent axon development in posterior lateral line nerve

description: The process whose specific outcome is the progression of an efferent axon in the posterior lateral line nerve over time from its formation to the mature structure. This process includes axonogenesis and pathfinding of the efferent axons in the posterior lateral line nerve.


histone H4S1 kinase activity

description: Catalysis of the reaction: histone H4-serine (position 1) + ATP = histone H4-phosphoserine (position 1) + ADP. This reaction is the addition of a phosphate group to the serine residue at position 1 of histone H4.


9,10-epoxystearate hydroxylase activity

description: Catalysis of the reaction: H+ + 9,10-epoxystearate + O2 + NADPH = 9,10-epoxy-18-hydroxystearate + H2O + NADP.


name: behavioral response to acetic acid induced pain

description: Any process that results in a change in the behaviour of an organism as a result of an acetic acid pain stimulus.


name: glucuronide:cation symporter activity

description: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucuronide(out) + monovalent cation(out) = glucuronide(in) + monovalent cation(in).


farnesol 2-isomerase activity

description: Catalysis of the reaction: 2-trans,6-trans-farnesol = 2-cis,6-trans-farnesol.


description: Catalysis of the reaction: (3R)-hydroxybutanoyl-[acyl-carrier-protein] = (2E)-butenoyl-[acyl-carrier-protein] + H2O.


embryonic root morphogenesis

description: The process in which the anatomical structures of the embryonic root are generated and organized.


meiotic DNA replication initiation

description: Any DNA replication initiation involved in meiotic cell cycle DNA replication.


trans-synaptic signaling by BDNF

description: Cell-cell signaling between presynapse and postsynapse mediated by brain-derived neurotrophic factor (BDNF) crossing the synaptic cleft.


description: Catalysis of the reaction: (2R)-3-sulfopropanediol(1-) + NAD = 2-oxo-3-hydroxy-propane-1-sulfonate + NADH + H+.


maintenance of RNA location

description: Any process in which RNA is maintained in a location and prevented from moving elsewhere.


name: telomeric DNA-containing double minutes formation

description: A telomere maintenance process that results in the formation of small fragments of circular extrachromosomal DNA elements which contain telomeric DNA. It is speculated that telomeric DNA-containing double minutes are formed through a recombination event between the telomere and chromosome-internal TTAGGG-like sequences. Telomeric DNA-containing double minutes appear as two closely positioned dots in metaphase.


novofumigatonin biosynthetic process

description: The chemical reactions and pathways resulting in the formation of novofumigatonin, a heavily oxygenated meroterpenoid containing a unique orthoester moiety.


name: positive regulation of R8 cell differentiation

description: Any process that activates or increases the frequency, rate or extent of R8 cell differentiation.


galactose uniporter activity

description: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: galactose (out) = galactose(in).


acetyl-CoA catabolic process

description: The chemical reactions and pathways resulting in the breakdown of acetyl-CoA, a derivative of coenzyme A in which the sulfhydryl group is acetylated.


name: signaling receptor ligand precursor processing

description: The cleavage of a peptide bond in a precursor form of a signaling receptor ligand, resulting in the mature (active) form of the ligand.


isochorismate pyruvate lyase activity

description: Catalysis of the reaction: isochorismate = salicylate + pyruvate.


ovarian fusome organization

description: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the fusome of ovarian cells, an organelle derived from the spectrosome. It anchors the mitotic spindle pole to provide orientation during cystoblast cell divisions.


name: regulation of branching involved in salivary gland morphogenesis by epithelial-mesenchymal signaling

description: Any process that modulates the rate, frequency, or extent of salivary gland branching as a result of the transfer of information from the epithelial cells to the mesenchymal cells of the salivary gland.


name: regulation of aggregation involved in sorocarp development

description: Any process that modulates the frequency, rate or extent of aggregation during sorocarp development. Aggregation involved in sorocarp development is the process whose specific outcome is the progression of the aggregate over time, from its formation to the point when a slug is formed. Aggregate development begins in response to starvation and continues by the chemoattractant-mediated movement of cells toward each other. The aggregate is a multicellular structure that gives rise to the slug.


name: fusion of sperm to egg plasma membrane involved in double fertilization forming a zygote and endosperm

description: The binding and fusion of a sperm, with the plasma membrane of the oocyte as part of the process of double fertilization forming a zygote and endosperm.


name: chemorepulsion of serotonergic neuron axon

description: The process in which a serotonergic neuron growth cone is directed to a specific target site in response to a repulsive chemical cue.


trans-synaptic signaling by lipid

description: Cell-cell signaling from post to pre-synapse, across the synaptic cleft, mediated by a lipid.


name: endonucleolytic cleavage in 3'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

description: Endonucleolytic cleavage within the 3'-External Transcribed Spacer (ETS) of a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, the 5.8S rRNA, and the Large Subunit (LSU) rRNA in that order from 5' to 3' along the primary transcript. In S. cerevisiae, endonucleolytic cleavage within the 3'-ETS of the pre-RNA, which may occur cotranscriptionally, is the first step in rRNA processing, and initiates a cascade of subsequent processing and modification events.


lactoferrin receptor activity

description: Combining with lactoferrin and delivering lactoferrin into the cell via endocytosis. Lactoferrin is an iron-binding glycoprotein which binds ferric iron most efficiently at low pH.


positive regulation of muscle atrophy

description: Any process that activates or increases the frequency, rate or extent of muscle atrophy.


name: azetidine-2-carboxylic acid acetyltransferase activity

description: Catalysis of the reaction: L-azetidine-2-carboxylic acid + acetyl-CoA = CoA-SH + N-acetyl azetidine-2-carboxylic acid.


regulation of trichome morphogenesis

description: Any process that modulates the frequency, rate or extent of trichome morphogenesis.


name: negative regulation of compound eye cone cell fate specification

description: Any process that restricts, stops or prevents a cell from specifying into a compound eye cone cell.


ent-isokaurene C2-hydroxylase activity

description: Catalysis of the reaction: ent-isokaurene + O2 + NADPH + H+ = ent-2alpha-hydroxyisokaurene + H2O + NADP+.


name: endocannabinoid signaling pathway involved in trans-synaptic signaling

description: Any endocannabinoid signaling pathway that is involved in trans-synaptic signaling by endocannabinoid.


name: negative regulation of long-term neuronal synaptic plasticity

description: A process that decreases long-term neuronal synaptic plasticity, the ability of neuronal synapses to change long-term as circumstances require. Long-term neuronal synaptic plasticity generally involves increase or decrease in actual synapse numbers.


homogalacturonan metabolic process

description: The chemical reactions and pathways involving homogalacturonan, a pectin characterized by a backbone of alpha-(1->4)-linked D-galacturonic acid residues that can be methyl-esterified at C-6 and carry acetyl groups on O-2 and O-3.


response to temozolomide

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a temozolomide stimulus.


name: C-C chemokine receptor CCR4 signaling pathway

description: The series of molecular signals initiated by a the C-C chemokine type 2 receptor (CCR4) on the surface of a cell binding to one of it's physiological ligands, and ending with the regulation of a downstream cellular process, e.g. transcription.


name: symbiont-mediated activation of host autophagy

description: A process in which a symbiont initiates, promotes, or enhances the activation of autophagy in the host cell. The host is defined as the larger of the organisms involved in a symbiotic interaction.


name: positive regulation of male mating behavior

description: Any process that activates or increases the frequency, rate or extent of male mating behavior.


name: protein localization to spindle microtubule

description: A process in which a protein is transported to, or maintained in, a location within a spindle microtubule.


GGA codon-amino acid adaptor activity

description: A triplet codon-amino acid adaptor activity that recognizes a GGA codon.


glutarate-CoA ligase activity

description: Catalysis of the reaction: ATP + CoA + glutarate = ADP + glutaryl-CoA + H+ + phosphate.


description: Catalysis of the reaction: N(5)-[1(S)-1-carboxyethyl]-L-ornithine + H2O + NADP+ = L-ornithine + H+ + NADPH + pyruvate.


name: cytoplasmic translational elongation through polyproline stretches

description: The successive addition of amino acid residues to a nascent polypeptide chain, proceeding through regions of multiple repeated proline codons, during protein biosynthesis in the cytoplasm.


nicotinate dehydrogenase activity

description: Catalysis of the reaction: H2O + NADP+ + nicotinate = 6-hydroxynicotinate + H+ + NADPH.


microvillar actin bundle assembly

description: Assembly of the parallel bundle of actin filaments at the core of a microvillus.


name: negative regulation of cellobiose catabolic process

description: Any process that stops, prevents or reduces the frequency, rate or extent of cellobiose catabolic process.


blood coagulation, common pathway

description: A protein activation cascade that contributes to blood coagulation and consists of events leading from the formation of activated factor X to the formation of active thrombin, the cleavage of fibrinogen by thrombin, and the formation of cleaved fibrin into a stable multimeric, cross-linked complex.


description: Catalysis of the reaction: a lipopolysaccharide + ADP-L-glycero-beta-D-manno-heptose = a heptosylated lipopolysaccharide + ADP + H+.


name: trinitrophenol hydride denitratase activity

description: Catalysis of the reaction: trinitrophenol hydride Meisenheimer complex = 2,4-dinitrophenol + nitrite. Trinitrophenol is also known as TNP.


name: peptidyl-S-diphytanylglycerol diether-L-cysteine biosynthetic process from peptidyl-cysteine

description: The modification of cysteine to form peptidyl-S-diphytanylglycerol diether-L-cysteine.


name: C-C chemokine receptor CCR7 signaling pathway

description: The series of molecular signals initiated by a the C-C chemokine type 7 receptor on the surface of a cell binding to one of it's physiological ligands, and ending with the regulation of a downstream cellular process, e.g. transcription.


3-sulfino-L-alanine binding

description: Binding to 3-sulfino-L-alanine (cysteine sulfinate).


description: Catalysis of the reaction: dimethylamine + a dimethylamine corrinoid protein = a methylated dimethylamine corrinoid protein + methylamine.


name: positive regulation of interleukin-35-mediated signaling pathway

description: Any process that increases the rate, frequency or extent of an interleukin-35-mediated signaling pathway.


name: lipopolysaccharide glucosyltransferase II activity

description: Catalysis of the reaction: lipopolysaccharide + UDP-D-glucose = D-glucosyl-lipopolysaccharide + UDP.


name: regulation of aminoacyl-tRNA ligase activity

description: Any process that modulates the frequency, rate or extent of aminoacyl-tRNA ligase activity.


name: positive regulation of sorocarp spore cell differentiation

description: Any process that activates or increases the frequency, rate or extent of sorocarp spore cell differentiation.


description: Catalysis of the reaction: N-acetyl-D-glucosaminyl-(1,3)-D-galactosyl-(1,4)-D-glucosylceramide + UDP-galactose = D-galactosyl-N-acetyl-D-glucosaminyl-(1,3)-D-galactosyl-(1,4)-D-glucosylceramide + UDP.


description: Catalysis of the reaction: S-adenosyl-L-methionine + glucuronoxylan D-glucuronate = S-adenosyl-L-homocysteine + glucuronoxylan 4-O-methyl-D-glucuronate.


N-malonylurea hydrolase activity

description: Catalysis of the reaction: 3-oxo-3-ureidopropanoate + H2O = H+ + malonate + urea.


response to desiccation

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a desiccation stimulus, extreme dryness resulting from the prolonged deprivation of water.


name: disruption of extracellular matrix of another organism

description: The chemical reactions and pathways performed by an organism resulting in the breakdown of the extracellular matrix of another organism.


name: complement component C3dg receptor activity

description: Combining with the C3dg product of the complement cascade and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


type III hypersensitivity

description: An inflammatory response resulting from recognition of immune complexes via complement or Fc receptors on effector cells leading to activation of neutrophils and other leukocytes and damage to bystander tissue.


name: cytosine:proton symporter activity

description: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: cytosine(out) + H+(out) = cytosine(in) + H+(in).


name: chemorepulsion of dopaminergic neuron axon

description: The process in which a dopaminergic neuron growth cone is directed to a specific target site in response to a repulsive chemical cue.


L-pipecolate oxidase activity

description: Catalysis of the reaction: L-pipecolate + O2 = 2,3,4,5-tetrahydropyridine-2-carboxylate + H2O2 + H+. Delta1-piperideine-6-carboxylate is also known as 2,3,4,5-tetrahydropyridine-2-carboxylate.


RNA polymerase activity

description: Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1); the synthesis of RNA from ribonucleotide triphosphates in the presence of a nucleic acid template.


cellular response to haloperidol

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a haloperidol stimulus.


name: determination of stomach left/right asymmetry

description: Determination of the asymmetric location of the stomach with respect to the left and right halves of the organism.


name: negative regulation of peptidoglycan recognition protein signaling pathway

description: Any process that decreases the rate, frequency, or extent of the peptidoglycan recognition protein signaling pathway.


beta-carotene metabolic process

description: The chemical reactions and pathways involving beta-carotene.


name: dimethyl selenide methyltransferase activity

description: Catalysis of the reaction: S-adenosyl-L-methionine + dimethyl selenide => S-adenosyl-L-homocysteine + trimethylselenonium.


(1->3)-beta-D-glucan binding

description: Binding to a (1->3)-beta-D-glucan.


delta7-sterol 5(6)-desaturase activity

description: Catalysis of the reaction: a delta(7)-sterol + 2 ferrocytochrome b5 + O2 + 2 H+ -> a delta(5,7)-sterol + 2 ferricytochrome b5 + 2 H2O.


hyoscyamine (6S)-dioxygenase activity

description: Catalysis of the reaction: 2-oxoglutarate + L-hyoscyamine + O2 = (6S)-6-hydroxyhyoscyamine + CO2 + succinate.


name: ocellus photoreceptor cell differentiation

description: The process in which a relatively unspecialized cell acquires specialized features of a photoreceptor cell found in the ocellus.


protein methylthiotransferase activity

description: Catalysis of the reaction: 2 S-adenosyl-L-methionine + a [ribosomal protein S12] L-aspartate89 + a sulfurated [sulfur carrier] + a reduced electron acceptor = S-adenosyl-L-homocysteine + L-methionine + 5'-deoxyadenosine + 2 H+ + a [ribosomal protein S12] 3-methylthio-L-aspartate89 + an unsulfurated [sulfur carrier] + an oxidized electron acceptor.


name: low-affinity glucose:sodium symporter activity

description: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose(out) + Na+(out) = glucose(in) + Na+(in). In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations.


egg deposition

description: The multicellular organismal reproductive process that results in the movement of an egg from within an organism into the external environment.


growth hormone receptor activity

description: Combining with a growth hormone and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


name: effector-mediated suppression of host defense response

description: A process mediated by a molecule secreted by a symbiont that results in the suppression of a defense response. The host is defined as the larger of the organisms involved in a symbiotic interaction.


name: modulation of relaxation of muscle in another organism

description: The process in which an organism effects a change in the relaxation of muscle in a second organism.


N-terminal peptidyl-glycine methylation

description: The methylation of the N-terminal glycine of proteins to form the derivative N-methylglycine.


name: 7-beta-hydroxysteroid dehydrogenase (NADP+) activity

description: Catalysis of the reaction: NADP+ + a 7-beta-hydroxysteroid = NADPH + H+ + a 7-oxosteroid.


maintenance of left sidedness

description: The organization process that preserves the left sidedness in an organism's body plan or part of an organism with respect to the left and right halves.


name: L-cysteine catabolic process via cystine, using cysteine transaminase

description: The chemical reactions and pathways resulting in the breakdown, via the compound cystine, of L-cysteine, catalyzed by the enzyme cysteine transaminase.


gellan lyase activity

description: Catalysis of the reaction: gellan = n beta-D-4-deoxy-delta4,5-GlcAp-(1->4)-beta-D-Glcp-(1->4)-alpha-L-Rhap-(1->3)-beta-D-Glcp. This reaction is the eliminative cleavage of beta-D-glucopyranosyl-(1->4)-beta-D-glucopyranosyluronate bonds of gellan backbone, releasing tetrasaccharides containing a 4-deoxy-4,5-unsaturated D-glucopyranosyluronic acid at the non-reducing end; in the product, the abbreviations are D-glucose (Glc), D-glucuronic acid (GlcA), and L-rhamnose (Rha).


description: Catalysis of the reaction: sucrose + 1,6-alpha-D-glucosyl(n) = 1,6-alpha-D-glucosyl(n+1) + fructose.


description: Catalysis of the reaction: N-nitrodimethylamine + O2 + 2 H+ + 2 e- = N-nitromethylamine + formaldehyde + H2O.


calcitriol binding

description: Binding to calcitriol. Calcitriol (1,25-dihydroxycholecalciferol) is the hormonally active form of vitamin D3.


name: methylammonium transmembrane transporter activity

description: Enables directed movement of methylammonium, CH3NH2, from one side of a membrane to the other.


AAC codon-amino acid adaptor activity

description: A triplet codon-amino acid adaptor activity that recognizes an AAC codon.


dalcochinase activity

description: Catalysis of the reaction: dalcochinin-8'-O-beta-glucoside + H2O = dalcochinin + D-glucopyranose.


description: Catalysis of the reaction: 2-oxoglutarate + LL-2,6-diaminopimelate = (S)-2,3,4,5-tetrahydrodipicolinate + L-glutamate + H2O + H+.


carnitine-CoA ligase activity

description: Catalysis of the reaction: D-carnitine + CoA + ATP = AMP + diphosphate + D-carnitinyl-CoA.


endosulfan ether monooxygenase activity

description: Catalysis of the reaction: endosulfan ether + O2 + 2 H+ + 2 e- = endosulfan hydroxyether + H2O.


linear vestibuloocular reflex

description: A vestibular reflex by which a response to a linear acceleration stimulus begins with an afferent nerve impulse from a receptor in the otolith and ends with the compensatory action of eye muscles. Signaling never reaches a level of consciousness.


name: neurotransmitter-mediated guidance of interneurons involved in substrate-independent cerebral cortex tangential migration

description: The response of migrating interneurons to neurotransmitters that alter electrical activity in cells in calcium dependent manner.


name: positive adaptation of signaling pathway

description: The positive regulation of a signal transduction pathway in response to a stimulus upon prolonged exposure to that stimulus.


protein depropionylation

description: The removal of a propionyl group from a residue in a peptide or protein.


description: Catalysis of the transfer of a methyl group to an acceptor molecule; dependent on the presence of 5-methyltetrahydropteroyltri-L-glutamate.


acetolactate synthase activity

description: Catalysis of the reaction: 2 pyruvate = 2-acetolactate + CO2.


description: Catalysis of the reaction: cis-zeatin + UDP-D-glucose = O-beta-D-glucosyl-cis-zeatin + H+ + UDP.


ketotetrose-phosphate aldolase activity

description: Catalysis of the reaction: L-erythrulose 1-phosphate = formaldehyde + glycerone phosphate.


trans-cinnamate-CoA ligase activity

description: Catalysis of the reaction: (E)-cinnamate + ATP + CoA = (E)-cinnamoyl-CoA + AMP + diphosphate.


baicalin beta-D-glucuronidase activity

description: Catalysis of the reaction: baicalin + H2O = baicalein + D-glucuronate.


myofibroblast contraction

description: The actin filament-based process in which cytoplasmic actin filaments slide past one another resulting in contraction of a myofibroblast.


name: antigen processing and presentation of endogenous peptide antigen via MHC class I via endolysosomal pathway

description: The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class I protein complex. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell and becomes associated with the MHC class I molecule in an endolysosome. Class I here refers to classical class I molecules.


deethylatrazine monooxygenase activity

description: Catalysis of the reaction: 2 deethylatrazine + O2 = 2 CH3COCH3 + 2 deisopropyldeethylatrazine.


metestrus

description: The estrous cycle phase in which there is subsiding follicular function.


aristolochene synthase activity

description: Catalysis of the reaction: trans,trans-farnesyl diphosphate = aristolochene + diphosphate.


description: Catalysis of the reaction: S-adenosyl-L-methionine + a 3-demethylubiquinol = S-adenosyl-L-homocysteine + a ubiquinol.


name: intermediate mesodermal cell fate determination

description: The process in which a cell becomes capable of differentiating autonomously into a intermediate mesoderm cell regardless of its environment; upon determination, the cell fate cannot be reversed.


apiose biosynthetic process

description: The chemical reactions and pathways resulting in the formation of apiose, the branched tetrose 3-C-(hydroxymethyl)-D-glycero-tetrose.


larval burrowing behavior

description: Digging into the substrate by non-feeding larvae in search for food-free sites suitable for pupation.


description: Catalysis of the reaction: S,S-dimethyl-beta-propiothetin = acrylate + dimethyl sulfide + H+.


hydroxylamine reductase activity

description: Catalysis of the reaction: NH3 + H2O + acceptor = hydroxylamine + reduced acceptor.


stachyose synthase activity

description: Catalysis of the reaction: 2 raffinose = stachyose + sucrose.


name: temporomandibular joint articular cartilage development

description: The process whose specific outcome is the progression of temporomandibular joint articular cartilage over time, from its formation to the mature structure.


name: proboscis morphogenesis, clypeo-labral disc-derived

description: The process in which the anatomical structures of the proboscis that are derived from the clypeo-labral disc are generated and organized.


description: Catalysis of the reaction: (6E)-8-hydroxygeranial + NADP = (6E)-8-oxogeranial + NADPH + H+.


name: termination of T cell signal transduction

description: The signaling process in which T cell signal transduction is brought to an end rather than being reversibly modulated.


regulation of astrocyte chemotaxis

description: Any process that modulates the frequency, rate or extent of astrocyte chemotaxis.


name: 24-ethylidenelophenol 4alpha-methyl oxidase activity

description: Catalysis of the reaction: 24-ethylidenelophenol + NADH + O2 + H+ = 4alpha-hydroxymethyl-stigmasta-7,24(241)-dien-3beta-ol + NAD + H2O.


name: vascular endothelial growth factor receptor signaling pathway involved in lymphatic endothelial cell fate commitment

description: The series of molecular signals generated as a consequence of vascular endothelial growth factor receptor binding to one of its physiological ligands that contributes to the commitment of a venous endothelial cell to a lymphatic endothelial cell fate.


trans-zeatin metabolic process

description: The chemical reactions and pathways involving trans-zeatin, (2E)-2-methyl-4-(9H-purin-6-ylamino)but-2-en-1-ol.


name: positive regulation of octopamine signaling pathway

description: Any process that activates or increases the frequency, rate or extent of octopamine signaling pathway.


name: anterior visceral endoderm cell migration

description: The orderly movement of an anterior visceral endoderm cell from one site to another.


description: The chemical reactions and pathways resulting in the breakdown of 1,5-anhydro-D-fructose.


description: Catalysis of the reaction: L-homocysteine + dimethylsulfonioacetate = (methylthio)acetate + L-methionine + H+.


name: cellular response to very low light intensity stimulus

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a very low light intensity stimulus. A very low light intensity stimulus is defined as a level of electromagnetic radiation below 0.001 mmol/m2/sec.


name: dorsal closure, spreading of leading edge cells

description: Dorsally-directed movement of a cell at the leading edge of the epithelium over the amnioserosa.


3-sulfolactaldehyde reductase activity

description: Catalysis of the reaction 2,3-dihydroxypropane-1-sulfonate + NAD+ = 3-sulfolactaldehyde + NADH + H+.


name: cystathionine gamma-synthase activity (acts on O-phosphohomoserine)

description: Catalysis of the reaction: L-cysteine + O-phosphonato-L-homoserine = L-cystathionine + hydrogenphosphate.


peptidyl-proline di-hydroxylation

description: The modification of peptidyl-proline to form trans-2,3-cis-3,4-dihydroxy-L-proline.


heterocyclic compound binding

description: Binding to heterocyclic compound.


description: Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N3-methylpseudouridine.


cytochrome c biosynthetic process

description: The chemical reactions and pathways resulting in the formation of cytochrome c.


name: cell-cell adhesion involved in synapse maturation

description: The attachment of the pre-synaptic cell to the post-synaptic cell via adhesion molecules that contributes to synapse maturation.


interleukin-28B production

description: The appearance of interleukin-28B due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


furylfuramide isomerase activity

description: Catalysis of the reaction: (E)-2-(2-furyl)-3-(5-nitro-2-furyl)acrylamide = (Z)-2-(2-furyl)-3-(5-nitro-2-furyl)acrylamide.


accessory nerve morphogenesis

description: The process in which the anatomical structure of the accessory nerve is generated and organized. The spinal branch of this motor nerve innervates the trapezius and the sternocleidomastoid muscles. The cranial branch joins the vagus nerve and innervates the same targets as the vagus nerve.


mRNA methylguanosine-cap decapping

description: Cleavage of the 5'-methylguanosine-cap of an mRNA. The methylguanosine-cap is present at the 5'-end of eukaryotic mRNAs. Decapping inactivates translation initiation and promotes 5'-to-3' decay of mRNA.


name: negative regulation of imaginal disc-derived wing size

description: Any process that reduces the size of an imaginal disc-derived wing.


protopanaxadiol 6-hydroxylase activity

description: Catalysis of the reaction: (20S)-protopanaxadiol + O2 + NADPH(4-) + H+ = protopanaxatriol + NADP + H2O.


name: regulation of viral DNA genome packaging via site-specific sequence recognition

description: Any process that modulates the frequency, rate or extent of viral DNA genome packaging via site-specific sequence recognition.


description: Catalysis of the reaction: 3-carboxy-2-hydroxy-4-methylpentanoate + NAD+ = 3-carboxy-4-methyl-2-oxopentanoate + NADH + H+.


name: regulation of cell population proliferation

description: Any process that modulates the frequency, rate or extent of cell proliferation.


response to diterpene

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diterpene stimulus.


name: benzaldehyde dehydrogenase (NADP+) activity

description: Catalysis of the reaction: benzaldehyde + NADP+ + H2O = benzoate + NADPH + H+.


glycosylceramide flippase activity

description: Catalysis of the movement of glycosylceramide from the exoplasmic to the cytosolic leaftlet of a membrane, using energy from the hydrolysis of ATP. Glycosylceramides are ceramides containing a functional group derived from a sugar.


cinnamic acid metabolic process

description: The chemical reactions and pathways involving cinnamic acid, 3-phenyl-2-propenoic acid.


hippocampal interneuron differentiation

description: The process in which a relatively unspecialized cell acquires specialized features of a hippocampal interneuron.


name: L-lysine efflux transmembrane transporter activity

description: Enables the transfer of L-lysine from the inside of the cell to the outside of the cell across a membrane.


description: Catalysis of the reaction: L-alanine + oxomalonate = aminomalonate + pyruvate.


sternite morphogenesis

description: The process in which the anatomical structures of the sternite are generated and organized. The sternite is the plate or sclerite on the underside of a body segment.


(R)-mevalonic acid metabolic process

description: The chemical reactions and pathways involving (R)-mevalonic acid.


name: indole glucosinolate biosynthetic process

description: The chemical reactions and pathways resulting in the formation of indole glucosinolates, sulfur-containing compounds that have a common structure linked to an R group derived from tryptophan.


phosphocreatine biosynthetic process

description: The chemical reactions and pathways resulting in the formation of phosphocreatine, a phosphagen of creatine which is synthesized and broken down by creatine phosphokinase.


name: negative regulation of cell proliferation in dorsal spinal cord

description: Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation in dorsal spinal cord.


name: mannitol transmembrane transporter activity

description: Enables the transfer of mannitol from one side of a membrane to the other. Mannitol is the alditol derived from D-mannose by reduction of the aldehyde group.


description: Catalysis of the reaction: 2-hydroxy-6-oxo-7-methylocta-2,4-dienoate + H2O = cis-2-hydroxypenta-2,4-dienoate + isobutyrate.


neuropeptide processing

description: Any protein maturation process achieved by the cleavage of a peptide bond or bonds within a neuropeptide precursor. Processing leads to the attainment of the full functional capacity of the neuropeptide.


description: Catalysis of the reaction: cis-3-phenylcyclohexa-3,5-diene-1,2-diol + NAD+ = biphenyl-2,3-diol + NADH + H+.


name: negative regulation of male germ-line stem cell asymmetric division

description: Any process that stops, prevents or reduces the frequency, rate or extent of male germ-line stem cell asymmetric division.


putrescine N-methyltransferase activity

description: Catalysis of the reaction: S-adenosyl-L-methionine + putrescine = N-methylputrescine + S-adenosyl-L-homocysteine + H+.


name: proteasomal proteolysis associated with antigen processing and presentation

description: The hydrolysis of a peptide bond or bonds within a protein by the proteasome complex contributing to antigen processing and presentation.


low-affinity IgA receptor activity

description: Combining with low affinity with an immunoglobulin of an IgA isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


name: negative regulation of oligodendrocyte progenitor proliferation

description: Any process that stops or decreases the rate or extent of oligodendrocyte progenitor proliferation.


name: positive regulation of midbrain dopaminergic neuron differentiation

description: Any process that activates or increases the frequency, rate or extent of midbrain dopaminergic neuron differentiation.


name: hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in nitriles

description: Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a nitrile, a compound containing the cyano radical, -CN.


description: Catalysis of the reaction: pelargonidin 3-O-beta-D-glucoside + UDP-alpha-D-glucose = anthocyanidin 3,5-di-O-beta-D-glucoside + UDP + H+.


name: positive regulation of cellotriose catabolic process

description: Any process that activates or increases the frequency, rate or extent of cellotriose catabolic process.


name: symbiont-mediated disruption of host phagosome

description: The process in which an organism effects a change that impairs the structure or function of host phagosomes.


ABC-type D-galactofuranose transporter

description: Catalysis of the reaction: alpha-D-galactofuranose + ATP + H2O = alpha-D-galactofuranose + hydrogenphosphate + ADP + H+.


name: negative regulation of CD8-positive, alpha-beta T cell extravasation

description: Any process that stops, prevents or reduces the frequency, rate or extent of CD8-positive, alpha-beta T cell extravasation.


name: establishment of septation initiation network asymmetry

description: The septation initiation signaling process by which the activity of the septation initiation network (SIN) is activated asymmetrically on the spindle pole bodies.


name: regulation of phosphate transmembrane transport

description: Any process that modulates the frequency, rate or extent of phosphate transmembrane transport.


carbapenem biosynthetic process

description: The chemical reactions and pathways resulting in the formation of carbapenem.


name: glycerol-1-phosphate dehydrogenase [NAD(P)+] activity

description: Catalysis of the reaction: NAD(P)+ + sn-glycerol-1-phosphate = NAD(P)H + H+ + dihydroxy-acetone-phosphate.


catechol 1,2-dioxygenase activity

description: Catalysis of the reaction: catechol + O2 = cis,cis-muconate.


helvolic acid biosynthetic process

description: The chemical reactions and pathways resulting in the formation of helvolic acid.


tetrose metabolic process

description: The chemical reactions and pathways involving a tetrose, any monosaccharide with a chain of four carbon atoms in the molecule.


4-hydroxybenzoate-CoA ligase activity

description: Catalysis of the reaction: ATP + 4-hydroxybenzoate + CoA = AMP + diphosphate + 4-hydroxybenzoyl-CoA.


tocopherol C-methyltransferase activity

description: Catalysis of the reaction: gamma-tocopherol + S-adenosyl-L-methionine = (+)-alpha-tocopherol + H+ + S-adenosyl-L-homocysteine. This reaction can also use delta-tocopherol, gamma-tocotrienol and delta-tocotrienol as substrates.


name: trans-synaptic signaling by neuropeptide, modulating synaptic transmission

description: Cell-cell signaling between presynapse and postsynapse, via the vesicular release and reception of neuropeptide molecules, that modulates the synaptic transmission properties of the synapse.


cellular response to tropane

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tropane stimulus. Tropane is a nitrogenous bicyclic organic compound mainly known for a group of alkaloids derived from it (called tropane alkaloids), which include, among others, atropine and cocaine.


butirosin metabolic process

description: The chemical reactions and pathways involving butirosin.


name: negative regulation of GABA-A receptor activity

description: Any process that stops, prevents or reduces the frequency, rate or extent of GABA-A receptor activity.


name: gibberellin A4 16alpha,17 epoxidase activity

description: Catalysis of the reaction: gibberellin A4 + O2 + H+ + NAD(P)H = 16alpha,17-epoxy gibberellin A4 + H2O + NAD(P).


iduronate-2-sulfatase activity

description: Catalysis of the hydrolysis of the 2-sulfate groups of the L-iduronate 2-sulfate units of dermatan sulfate, heparan sulfate and heparin.


response to cobalamin

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cobalamin (vitamin B12) stimulus.


vicianin beta-glucosidase activity

description: Catalysis of the reaction: (R)-vicianin + H2O = mandelonitrile + vicianose.


name: GMP synthase (glutamine-hydrolyzing) activity

description: Catalysis of the reaction: ATP + XMP + L-glutamine + H2O = AMP + diphosphate + GMP + L-glutamate + 2H+.


name: diacetyl reductase ((R)-acetoin forming) activity

description: Catalysis of the reaction: (R)-acetoin + NAD+ = diacetyl + H+ + NADH.


name: histone H3K9 dimethyltransferase activity

description: Catalysis of the reaction: L-lysyl9-[histone H3] + 2 S-adenosyl-L-methionine = 2 H+ + N6,N6-dimethyl-L-lysyl9-[histone H3] + 2 S-adenosyl-L-homocysteine. This reaction is the successive addition of two methyl groups to the unmethylated lysine residue at position 9 of histone H3, producing histone H3K9me2.


name: positive regulation of complement activation, alternative pathway

description: Any process that activates or increases the frequency, rate or extent of complement activation by the alternative pathway.


name: negative regulation of paraxial mesodermal cell fate determination

description: Any process that stops, prevents, or reduces the frequency, rate or extent of paraxial mesoderm cell fate determination.


name: modulation by host of symbiont type IV pilus-dependent motility

description: The process in which an organism effects a change in the type IV pilus-dependent motility of a symbiont organism (i.e. the controlled movement of a bacterial cell which is dependent on the presence of type IV pili, and which includes social gliding motility and twitching motility). The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.


name: entry into host cell by a symbiont-containing vacuole

description: The invasion by a symbiont of a cell of a host organism, forming a vacuole in which the symbiont resides. The vacuole membrane is formed from lipids and proteins derived from both host and symbiont. Begins when the symbiont attaches on to the host cell membrane which invaginates and deepens as the symbiont enters, and ends when the host cell membrane closes behind the newly-formed vacuole.


name: symbiont-mediated suppression of host translation initiation

description: A process in which a symbiont inhibits or disrupts translation initiation in its host. The host is defined as the larger of the organisms involved in a symbiotic interaction.


L-sorbose biosynthetic process

description: The chemical reactions and pathways resulting in the formation of L-sorbose, the L-enantiomer of the ketohexose xylo-2-hexulose. L-sorbose is formed by bacterial oxidation of sorbitol.


peptidyl-lysine guanylylation

description: The guanylylation of peptidyl-lysine to form peptidyl-N6-(phospho-5'-guanosine)-L-lysine.


name: negative regulation of voltage-gated calcium channel activity in another organism

description: Any process in which an organism stops, prevents or reduces the frequency, rate or extent of the activity of a voltage-gated calcium channel in another organism. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.


name: biosynthetic process of antibacterial peptides active against Gram-positive bacteria

description: The chemical reactions and pathways resulting in the formation of an antibacterial peptide with activity against Gram-positive bacteria.


description: The chemical reactions and pathways involving 3-(3-hydroxyphenyl)propanoate.


isonocardicin synthase activity

description: Catalysis of the reaction: S-adenosyl-L-methionine(1+) + nocardicin E = S-methyl-5'-thioadenosine + H+ + isonocardicin A.


name: positive regulation of neuronal action potential

description: Any process that activates or increases the frequency, rate or extent of neuronal action potential.


cellular response to cycloalkane

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cycloalkane stimulus. A cycloalkane is a cyclic saturated hydrocarbon having the general formula CnH2n.


macromolecule modification

description: The covalent alteration of one or more monomeric units in a polypeptide, polynucleotide, polysaccharide, or other biological macromolecule, resulting in a change in its properties.


cellular response to freezing

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a freezing stimulus, temperatures below 0 degrees Celsius.


histone H3K deacetylase activity

description: Catalysis of the reaction: histone H3 N6-acetyl-L-lysine + H2O = histone H3 L-lysine + acetate. This reaction represents the removal of an acetyl group from a histone H3.


xylose isomerase activity

description: Catalysis of the reaction: D-xylose = D-xylulose.


description: Catalysis of the reaction: (S)-naringenin + S-adenosyl-L-methionine = 2 H+ + ponciretin + S-adenosyl-L-homocysteine.


perchlorate reductase activity

description: Catalysis of the reaction: perchlorate + 2 H+ + 2 e- = chlorate + H2O.


name: symbiont-mediated perturbation of host NF-kappaB cascade

description: A process in which a symbiont alters or subverts an NF-kappaB-mediated signaling cascade in its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.


taxis to electron acceptor

description: The directed movement of a motile cell or organism in response to the presence of an alternative electron acceptor, for example, nitrate.


GUG codon-amino acid adaptor activity

description: A triplet codon-amino acid adaptor activity that recognizes a GUG codon.


U2 snRNP binding

description: Binding to a U2 small nuclear ribonucleoprotein particle.


name: regulation of fungal-type cell wall (1->3)-alpha-glucan metabolic process

description: Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in the walls of ascospores.


name: natural killer cell inhibitory signaling pathway

description: The series of molecular signals initiated by an extracellular ligand binding to a receptor on the surface of a natural killer cell capable of inhibiting an immune effector process contributing to an immune response.


carveol dehydrogenase activity

description: Catalysis of the reaction: (1S,5R)-carveol + NADP+ = (R)-carvone + H+ + NADPH.


name: Notch signaling pathway involved in forebrain neuroblast division

description: The series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell that contributes to the self renewal of neuroblasts in the forebrain.


albendazole monooxygenase activity

description: Catalysis of the reaction: albendazole + H+ + NADPH + O2 = albendazole S-oxide + H2O + NADP+.


name: left ventricular compact myocardium morphogenesis

description: The process in which the anatomical structures of cardiac left ventricular compact myocardium are generated and organized.


prostaglandin catabolic process

description: The chemical reactions and pathways resulting in the breakdown of prostaglandin.


regulation of biosynthetic process

description: Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances.


name: regulation of hemicellulose catabolic process

description: Any process that modulates the frequency, rate or extent of hemicellulose catabolic process.


name: vasodilation involved in acute inflammatory response

description: An increase in the internal diameter of blood vessels, especially arterioles or capillaries, usually resulting in a decrease in blood pressure contributing to an acute inflammatory response.


lactoyl-CoA dehydratase activity

description: Catalysis of the reaction: lactoyl-CoA = acryloyl-CoA + H2O.


description: Catalysis of the reaction: L-glutamate 5-semialdehyde + NADP+ + phosphate = L-glutamyl 5-phosphate + H+ + NADPH.


name: FAD-dependent urate hydroxylase activity

description: Catalysis of the reaction: 7,9-dihydro-1H-purine-2,6,8(3H)-trione + NADH + H+ + O2 = 5-hydroxyisouric acid + NAD + H2O.


name: positive regulation of cardiac epithelial to mesenchymal transition

description: Any process that starts or increases the rate, frequency or extent of cardiac epithelial to mesenchymal transition, a transition where a cardiac epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.


description: Catalysis of the reaction: 3-hydroxyanthranilate + S-adenosyl-L-methionine = 3-hydroxy-4-methylanthranilate + S-adenosyl-L-homocysteine + H+.


name: lipopolysaccharide transmembrane transporter activity

description: Enables the transfer of lipopolysaccharides from one side of a membrane to the other. A lipopolysaccharide is any of a group of related, structurally complex components of the outer membrane of Gram-negative bacteria. Lipopolysaccharides consist three covalently linked regions, lipid A, core oligosaccharide, and an O side chain. Lipid A is responsible for the toxicity of the lipopolysaccharide.


name: negative regulation of collecting lymphatic vessel constriction

description: Any process that stops, prevents or reduces the frequency, rate or extent of collecting lymphatic vessel constriction.


cysteine-type exopeptidase activity

description: Catalysis of the hydrolysis of C- or N-terminal peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile.


D-leucine catabolic process

description: The chemical reactions and pathways resulting in the breakdown of D-leucine.


acetate fermentation

description: The anaerobic chemical reactions and pathways resulting in the breakdown of acetate, yielding energy in the form of ATP.


name: anthocyanin-containing compound metabolic process

description: The chemical reactions and pathways involving anthocyanins, any member of a group of intensely colored soluble glycosides of anthocyanidins that occur in plants. They are responsible from most of the scarlet, purple, mauve and blue coloring in higher plants, especially of flowers.


name: symbiont-mediated suppression of host reactive oxygen species generation

description: A process in which a symbiont interferes with, inhibits or disrupts the host signal transduction pathways leading to the production of reactive oxygen species as part of the host innate immune response. The host is defined as the larger of the organisms involved in a symbiotic interaction.


substituted mannan metabolic process

description: The chemical reactions and pathways involving a mannan backbone composed of D-mannose unites, substituted with D-glucose and/or D-galactose units.


DIF dechlorinase activity

description: Catalysis of the reaction: 1-[(3,5-dichloro-2,6-dihydroxy-4-methoxy)phenyl]hexan-1-one => 1-[(3-chloro-2,6-dihydroxy-4-methoxy)phenyl]hexan-1-one + Cl-.


detection of maltose stimulus

description: The series of events in which a maltose stimulus is received by a cell and converted into a molecular signal.


description: Catalysis of the reaction: 2,4',7-trihydroxyisoflavanone + S-adenosyl-L-methionine = H+ + 2,7-dihydroxy-4'-methoxyisoflavanone + S-adenosyl-L-homocysteine.