name: somatic diversification of immune receptors via gene conversion

description: The process in which immune receptor genes are diversified through gene conversion.


ADP-thymidine kinase activity

category: biolink:MolecularActivity biolink:Occurrent biolink:OntologyClass biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: Catalysis of the reaction: ADP + thymidine = AMP + thymidine 5'-phosphate.


name: embryonic ectodermal digestive tract morphogenesis

category: biolink:BiologicalProcess biolink:Occurrent biolink:OntologyClass biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: The process, occurring during the embryonic phase, by which the anatomical structures of the ectodermal digestive tract are generated and organized.


description: Catalysis of the reaction: GDP-4-amino-4,6-dideoxy-alpha-D-mannose + 2-oxoglutarate = GDP-4-dehydro-6-deoxy-alpha-D-mannose + L-glutamate.


name: positive regulation of maltotriulose transport

description: Any process that activates or increases the frequency, rate or extent of maltotriulose transport.


integrated stress response signaling

category: biolink:Pathway biolink:OntologyClass biolink:BiologicalProcess biolink:Occurrent biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: The series of molecular signals generated in response to diverse stress stimuli required to restore cellular homeostasis. The core event in this pathway is the phosphorylation of eIF2 alpha by one of four members of the eIF2a kinase family (EIF2AK1/HRI, EIF2AK2/PKR, EIF2AK3/PERK and EIF2AK4/GCN2), which leads to a decrease in global protein synthesis and the induction of selected genes, including the transcription factor ATF4, that together promote cellular recovery.


O-succinyltransferase activity

description: Catalysis of the transfer of a succinyl group to an oxygen atom on the acceptor molecule.


proteasome core complex assembly

description: The aggregation, arrangement and bonding together of a mature, active 20S proteasome core particle complex that does not contain any regulatory particles.


spinal cord interneuron axon guidance

description: The process in which the migration of an axon growth cone of a spinal cord interneuron is directed to a specific target site in response to a combination of attractive and repulsive cues. A spinal cord interneuron is a CNS interneuron located in the spinal cord.


nuclear capsid assembly

description: The assembly of a virus capsid that occurs in the nucleus. The assembly of large icosahedral shells for herpesviridae and adenoviridae requires structural proteins that act as chaperones for assembly.


description: Catalysis of the reaction: UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine + L-alanyl-tRNA(Ala) = UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-N6-(L-alanyl)-L-lysyl-D-alanyl-D-alanine + tRNA(Ala).


detection of folic acid

description: The series of events in which a folic acid stimulus is received by a cell and converted into a molecular signal.


name: regulation of septation initiation signaling

description: Any process that modulates the frequency, rate or extent of septation initiation signaling.


ion binding

description: Binding to an ion, a charged atoms or groups of atoms.


name: determination of intestine left/right asymmetry

description: Determination of the asymmetric location of the intestine loops with respect to the left and right halves of the organism.


description: Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing 2'-O-methylcytosine.


hexitol dehydrogenase activity

description: Catalysis of the reaction: hexitol + acceptor = hexose + reduced acceptor.


name: negative regulation of otic vesicle morphogenesis

description: Any process that stops, prevents or reduces the frequency, rate or extent of otic vesicle morphogenesis.


description: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: monocarboxylate(out) + Na+(out) = monocarboxylate(in) + Na+(in).


name: glucuronoside transmembrane transporter activity

description: Enables the transfer of a glucuronosides from one side of a membrane to the other. Glucuronosides are any compound formed by combination of glycosidic linkage of a hydroxy compound (e.g. an alcohol or a saccharide) with the anomeric carbon atom of glucuronate.


interferon-epsilon production

description: The appearance of interferon-epsilon due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


response to cyclopentenone

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cyclopentenone stimulus. Cyclopentenones are oxylipins derived from polyunsaturated fatty acids. They are structurally similar to jasmonic acid, but contain a reactive unsaturated carbonyl structure in the cyclo-ring. Cyclopentenones include phytoprostanes and 12-oxo-phytodienoic acid.


positive regulation of cilium movement

description: Any process that increases the rate, frequency, or extent of cilium movement, the directed, self-propelled movement of a cilium.


haltere development

description: The process whose specific outcome is the progression of the haltere over time, from its formation to the mature structure. The haltere is the club-shaped 'balancers' found on each side of the metathorax among the true flies (Diptera). They are the much-modified hind wings.


homoserine biosynthetic process

description: The chemical reactions and pathways resulting in the formation of homoserine, alpha-amino-gamma-hydroxybutyric acid.


zygotene

description: The cell cycle phase which follows leptotene during prophase I of meiosis, and during which each chromosome pairs with its homolog; the two become aligned and crossing over may occur.


name: planar cell polarity pathway involved in ventricular septum morphogenesis

description: The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity that contributes to the shaping of the ventricular septum.


name: L-tryptophan transmembrane transporter activity

description: Enables the transfer of L-tryptophan from one side of a membrane to the other. Tryptophan is 2-amino-3-(1H-indol-3-yl)propanoic acid.


5-aminolevulinate-CoA ligase activity

description: Catalysis of the reaction: 5-ammoniolevulinate + coenzyme A + ATP = 5-aminolevulinyl-CoA + AMP + diphosphoric acid.


name: single-strand selective uracil DNA N-glycosylase activity

description: Catalysis of the cleavage of the N-C1' glycosidic bond between the damaged DNA base and the deoxyribose sugar, releasing a free base and leaving an apyrimidinic (AP) site. Enzymes with this activity recognize and remove uracil bases present in single-stranded DNA.


name: iron incorporation into iron-sulfur cluster via tris-L-cysteinyl-L-aspartato diiron disulfide

description: The incorporation of iron into a 2Fe-2S iron-sulfur cluster via tris-L-cysteinyl-L-aspartato diiron disulfide.


name: copal-8-ol diphosphate synthase activity

description: Catalysis of the reaction: copal-8-ol diphosphate = 2-trans,6-trans,10-trans-geranylgeranyl diphosphate + H2O.


name: UDP-D-glucose:delphinidin 3-O-glucosyl-5-O-caffeoylglucoside -O-beta-D-glucosyltransferase activity

description: Catalysis of the reaction: UDP-alpha-D-glucose + delphinidin 3-O-glucosyl-5-O-caffeoylglucoside = H+ + delphinidin 3-O-glucosyl-5-O-(caffeoylglucoside-3'-O-glucoside) + UDP.


name: fungal-type cell wall (1->3)-beta-D-glucan metabolic process

description: The chemical reactions and pathways involving (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds, found in the walls of fungi.


name: positive regulation of positive thymic T cell selection

description: Any process that activates or increases the frequency, rate or extent of positive thymic T cell selection.


rolling circle viral DNA replication

description: A process of unidirectional viral DNA replication that takes place on a circular DNA to rapidly produce numerous copies of the viral genome. Involves creating a nick in one strand of the circular DNA molecule at the origin of replication. DNA is then synthesized by DNA polymerase. Using the non-nicked strand as a template, replication proceeds around the circular DNA molecule, displacing the nicked strand as single-stranded DNA.


apical dendrite arborization

description: The process in which the anatomical structures of a dendritic tree are generated on the apical neuron side and organized into dendritic branches.


maltose glucosidase activity

description: Catalysis of the reaction: H2O + maltose = 2 glucose.


name: negative regulation of branch elongation involved in ureteric bud branching

description: Any process that reduces the frequency, rate or extent of branch elongation involved in ureteric bud branching, the growth of a branch of the ureteric bud along its axis.


name: negative regulation of microglia differentiation

description: Any process that stops, prevents, or reduces the frequency, rate or extent of microglia differentiation, the process in which a relatively unspecialized cell acquires specialized features of a microglial cell.


name: light-independent chlorophyll biosynthetic process

description: The chemical reactions and pathways resulting in the formation of chlorophyll, any compound of magnesium complexed in a porphyrin (tetrapyrrole) ring and which functions as a photosynthetic pigment, from less complex precursors, which occur in the absence of light.


response to strigolactone

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a strigolactone stimulus.


quinate 3-dehydrogenase (NAD+) activity

description: Catalysis of the reaction: (-)-quinate + NAD+ = (-)-3-dehydroquinate + NADH + H+.


negative energy taxis

description: The directed movement of a motile cell or organism towards a lower level of a physical stimulus involved in energy generation, such as light, oxygen, and oxidizable substrates.


callose deposition in cell wall

description: Any process in which callose is transported to, and/or maintained in, the cell wall. Callose is a linear 1,3-beta-d-glucan formed from UDP-glucose and is found in certain plant cell walls.


description: Catalysis of the reaction: 7,8-dihydroxykynurenate + O2 = 5-(3-carboxylato-3-oxoprop-1-en-1-yl)-4,6-dihydroxypyridine-2-carboxylate + H+.


seed maturation

description: A process in seed development that occurs after embryogenesis by which a quiescent state is established in a seed. Seed maturation is characterized by storage compound accumulation, acquisition of desiccation tolerance, growth arrest and the entry into a dormancy period of variable length that is broken upon germination.


name: transmembrane ascorbate ferrireductase activity

description: Oxidation of Fe(3+) to Fe(2+) on the outer side of a membrane coupled to the reduction of L-ascorbate to monodehydro-L-ascorbate radical on the inner side of a membrane. Electrons get transferred across the membrane during the reaction.


name: p-benzoquinone reductase (NADPH) activity

description: Catalysis of the reaction: 1,4-benzoquinone + H+ + NADPH = hydroquinone + NADP+.


name: cell proliferation involved in pronephros development

description: The multiplication or reproduction of cells, resulting in the expansion of the population in the pronephros.


name: establishment or maintenance of cytoskeleton polarity involved in ameboidal cell migration

description: Any cellular process that results in the specification, formation or maintenance of polarized cytoskeletal structures that contribute to the cell polarity of a migrating ameboid cell.


name: positive regulation of spore encystment on host

description: Any process that activates, maintains or increases the frequency, rate or extent of spore encystment on host. The host is defined as the larger of the organisms involved in a symbiotic interaction.


ascaroside metabolic process

description: The chemical reactions and pathways involving ascaroside.


arginine N-succinyltransferase activity

description: Catalysis of the reaction: succinyl-CoA + L-arginine = CoA + N2-succinyl-L-arginine.


sterigmatocystin metabolic process

description: The chemical reactions and pathways involving sterigmatocystin, a carcinogenic mycotoxin produced in high yields by strains of the common molds.


name: nucleoside oxidase (hydrogen peroxide-forming) activity

description: Catalysis of the reactions: adenosine + 2 O2 = 9-riburonosyladenine + 2 hydrogen peroxide.


name: anaerobic cyclohexane-1-carboxylate catabolic process

description: The chemical reactions and pathways resulting in the breakdown of cyclohexane-1-carboxylate, a alicyclic acid, in the absence of oxygen.


name: positive regulation of platelet-derived growth factor receptor-beta signaling pathway

description: Any process that activates or increases the frequency, rate or extent of platelet-derived growth factor receptor-beta signaling pathway.


name: positive regulation of ureter smooth muscle cell differentiation

description: Any process that activates or increases the frequency, rate or extent of ureter smooth muscle cell differentiation.


hydroxyquinol 1,2-dioxygenase activity

description: Catalysis of the reaction: benzene-1,2,4-triol + O2 = 3-hydroxy-cis,cis-muconate + 2 H+.


terpene catabolic process

description: The chemical reactions and pathways resulting in the breakdown of terpenes, any of a large group of hydrocarbons made up of isoprene units.


name: morphogenesis of an epithelial fold involved in embryonic heart tube formation

description: The morphogenetic process in which an epithelial sheet bends along a linear axis, contributing to embryonic heart tube formation.


name: positive regulation of motor neuron apoptotic process

description: Any process that activates or increases the frequency, rate or extent of motor neuron apoptotic process.


oral incubation

description: A parental behavior in which fertilized eggs are taken into the mouth and held until hatching.


chondrocyte activation

description: A change in the morphology or behavior of a chondrocyte resulting from exposure to an activating factor such as a cellular or soluble ligand. A chondrocyte is a polymorphic cell that forms cartilage.


pre-mRNA catabolic process

description: The chemical reactions and pathways resulting in the breakdown of the unspliced pre-mRNA (pre-messenger RNA).


glucan 1,6-alpha-glucosidase activity

description: Catalysis of the hydrolysis of (1->6)-alpha-D-glucosidic linkages in (1->6)-alpha-D-glucans and derived oligosaccharides.


butanediol catabolic process

description: The chemical reactions and pathways resulting in the breakdown of butanediol; the biologically relevant isomer is 2,3-butanediol, CH3CH(OH)CH(OH)CH3.


positive regulation of strand invasion

description: Any process that increases the rate, frequency or extent of strand invasion. Strand invasion is the process in which the nucleoprotein complex (composed of the broken single-strand DNA and the recombinase) searches and identifies a region of homology in intact duplex DNA. The broken single-strand DNA displaces the like strand and forms Watson-Crick base pairs with its complement, forming a duplex in which each strand is from one of the two recombining DNA molecules.


name: thiol-driven fumarate reductase activity

description: Catalysis of the reaction: fumarate + coenzyme M + coenzyme B = succinate + coenzyme M + coenzyme B + heterodisulfide.


name: symbiont-mediated non-specific activation of host T-cells

description: A process by which a symbiont superantigen elicits a strong immune response by activating a large number of T cells in a non-specific manner. Unlike conventional antigens, which activate T cells by interacting with specific receptors on the surface of these cells, superantigens can stimulate T cells by binding to regions outside the antigen-binding site. Superantigens can activate a large proportion of T cells, leading to an exaggerated immune response. This excessive activation can result in the release of a large amount of cytokines such as tumor necrosis factor and interleukin-2. The massive cytokine release can lead to an acute toxic shock, causing symptoms such as fever and organ damage.


name: positive regulation of activated CD4-positive, alpha-beta T cell apoptotic process

description: Any process that activates or increases the frequency, rate or extent of activated CD4-positive, alpha-beta T cell apoptotic process.


pyrimidine deoxyribonucleotide binding

description: Binding to a pyrimidine deoxyribonucleotide, any compound consisting of a pyrimidine deoxyribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the deoxyribose moiety.


name: L-methionine secondary active transmembrane transporter activity

description: Enables the transfer of L-methionine from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters.


name: determination of left/right asymmetry in nervous system

description: The establishment of the nervous system with respect to the left and right halves.


name: envenomation resulting in blood vessel extracellular matrix damage, causing hemorrhagic damage in another organism

description: A process that begins with venom being forced into an organism by the bite or sting of another organism which causes damage to the extracellular matrix of the blood vessels of the bitten organism, ultimately resulting in hemorrhage in the bitten organism.


name: chondrocyte intercalation involved in growth plate cartilage morphogenesis

description: The orderly movement of a chondrocyte from one site to another that contributes to the shaping of growth plate cartilage in an endochondral bone.


name: inositol heptakisphosphate 5-kinase activity

description: Catalysis of the reaction: ATP + 4-diphospho-1D-myo-inositol (1,2,3,5,6)pentakisphosphate = 4,5-bisdiphosphoinositol-1D-myoinositol (1,2,3,6)tetrakisphosphate, and ATP + 6-diphospho-1D-myo-inositol (1,2,3,4,5)pentakisphosphate = 5,6-bisdiphosphoinositol-1D-myoinositol (1,2,3,4)tetrakisphosphate.


name: monodehydroascorbate reductase (NADH) activity

description: Catalysis of the reaction: NADH + H+ + 2 monodehydroascorbate = NAD+ + 2 ascorbate.


name: oxidoreductase activity, acting on the CH-NH2 group of donors, with a quinone or similar compound as acceptor

description: Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and reduces a quinone or similar compound.


squalene synthase activity

description: Catalysis of the reaction: presqualene diphosphate + NADPH = squalene + NADP+ + diphosphate.


description: Catalysis of the reaction: 1-O-(indol-3-ylacetyl)-beta-D-glucose + H2O = H+ + indole-3-acetate + beta-D-glucose.


7-oxatyphasterol synthase activity

description: Catalysis of the reaction: H+ + typhasterol + NADPH + O2 = 7-oxatyphasterol + NADP + H2O.


adult visceral muscle development

description: The process whose specific outcome is the progression of the adult visceral muscle over time, from its formation to the mature structure.


nicotianamine metabolic process

description: The chemical reactions and pathways involving nicotianamine, 2(S),3'2(S),3''(S)-N-(N-(3-amino-3-carboxypropyl)-3-amino-3-carboxypropyl)-azetidine-2-carboxylic acid.


description: Catalysis of the reaction: all-trans-beta-carotene + O2 = 2 all-trans-retinal.


description: Catalysis of the reaction: an aromatic amino acid + 2-oxoglutarate = an aromatic oxo acid + L-glutamate.


name: anaerobic catabolism of pairs of amino acids

description: The anaerobic chemical reactions and pathways resulting in the breakdown of amino acids; in these reactions, one amino acid is oxidised (acts as an electron donor) and a different amino acid is reduced (acts as an electron acceptor); oxidation of the electron-donating amino acid yields energy in the form of ATP.


name: chemokine (C-C motif) ligand 1 production

description: The appearance of chemokine (C-C motif) ligand 1 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


hemocyte development

description: The process whose specific outcome is the progression of the hemocyte over time, from its formation to the mature structure. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen.


guanidinobutyrase activity

description: Catalysis of the reaction: 4-guanidinobutanoate + H2O = 4-aminobutanoate + urea.


mesenchymal stem cell proliferation

description: The multiplication or reproduction of mesenchymal stem cells, resulting in the expansion of a stem cell population. A mesenchymal stem cell, or MSC, is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells.


name: zeinoxanthin epsilon hydroxylase activity

description: Catalysis of the reaction: zeinoxanthin + NADPH + O2 + H+ = lutein + NADP+ + H2O. Adds a hydroxyl group to the epsilon ring of the alpha-carotene.


name: trimethyluric acid monooxygenase activity

description: Catalysis of the reaction: 1,3,7-trimethyluric acid + O2 + NADH + 3 H+ = 1,3,7-trimethyl-5-hydroxyisourate + NAD + H2O.


tetrahydrocorphin metabolic process

description: The chemical reactions and pathways involving tetrahydrocorphins, tetrapyrroles that combine the structural elements of both porphyrins and corrins.


name: negative regulation of ornithine catabolic process

description: Any process that stops, prevents or reduces the frequency, rate or extent of ornithine catabolic process.


histone H2B acetyltransferase activity

description: Catalysis of the reaction: acetyl-CoA + histone H2B L-lysine = CoA + histone H2B N6-acetyl-L-lysine.


caudal fin morphogenesis

description: The process in which the anatomical structures of the caudal fin are generated and organized. A caudal fin is an unpaired medial fin mounted at the caudal end of the fish, and is the main fin used for propulsion.


name: negative regulation of meiotic joint molecule formation

description: Any process that decreases the frequency, rate or extent of meiotic joint molecule formation. Meiotic joint molecule formation is the conversion of the paired broken DNA and homologous duplex DNA into a four-stranded branched intermediate, known as a joint molecule, formed during meiotic recombination.


pyochelin biosynthetic process

description: The chemical reactions and pathways resulting in the formation of the siderochrome pyochelin (2-(2-o-hydroxyphenyl-2-thiazolin-4-yl)-3-methylthiazolidine-4-carboxylic acid).


description: Catalysis of the reaction: H+ + uracil 5-carboxylate = CO2 + uracil.


name: symbiont-mediated perturbation of host opsonization

description: A process in which a symbiont alters or subverts opsonization by the host. The host is defined as the larger of the organisms involved in a symbiotic interaction.


L-lysine 4-chlorinase activity

description: Catalysis of the reaction: 2-oxoglutarate + chloride + H+ + L-lysine + O2 = 4-chloro-L-lysine + CO2 + H2O + succinate.


tyrosine phenol-lyase activity

description: Catalysis of the reaction: L-tyrosine + H2O = NH4 + phenol + pyruvate.


propane-1,3-diamine oxidase activity

description: Catalysis of the reaction: propane-1,3-diamine + H2O + O2 = 3-aminopropanal + NH3 + hydrogen peroxide + H+.


alpha-1,4-mannosyltransferase activity

description: Catalysis of the transfer of a mannose residue to an oligosaccharide, forming an alpha-(1->4) linkage.


name: thiosulfate transmembrane transporter activity

description: Enables the transfer of thiosulfate ions, HS2O3(1-), from one side of a membrane to the other.


name: 9,12-cis-hexadecadienoic acid delta 15 desaturase activity

description: Catalysis of the reaction: (9Z,12Z)-hexadecadienoyl-CoA + O2 + a reduced electron acceptor = 9,12,15-cis-hexadecatrienoyl-CoA + 2 H2O + an oxidized electron acceptor.


description: Catalysis of the reaction: S-substituted L-cysteine + acetyl-CoA = S-substituted N-acetyl-L-cysteine + CoA + H+.


GDP-glucosidase activity

description: Catalysis of the reaction: GDP-D-glucose + H2O = D-glucose + GDP + H+.


name: epithelial cell migration involved in distal tubule morphogenesis

description: The orderly movement of epithelial cells within a renal tubule that contributes to distal tubule morphogenesis.


chlorobenzene dioxygenase activity

description: Catalysis of the reaction: 2,3-unsubstituted benzenoid + O2 + NAD(P)H + H+ = 2,3-cis-dihydroxydihydrobenzenoid + NAD(P)+. Substrates include 1,4-dichlorobenzene (forms 3,6-dichloro-cis-1,2-dihydroxycyclohexa-3,5-diene), 1,2,3,4-tetrachlorobenzene (forms cis-chlorobenzene dihydrodiol) and 1,2,4-trichlorobenzene (forms 3,4,6-trichloro-cis-1,2-dihydroxycyclohexa-3,5-diene).


description: Catalysis of the reaction: (R)-5-diphosphomevalonate + ATP = ADP + CO2 + H+ + isopentenyl diphosphate + phosphate.


description: Catalysis of the reaction: 4-guanidinobutanal + H2O + NAD+ = 4-guanidinobutanoate + 2 H+ + NADH.


name: endonucleolytic cleaveage between 4.5S rRNA and 5S rRNA of tetracistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 4.5S-rRNA, 5S-rRNA)

description: Endonucleolytic cleavage between the 5S rRNA and the 4.5S rRNA of an rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 4.5S rRNA, and the 5S rRNA in that order from 5' to 3' along the primary transcript. Note that the use of the word tetracistronic refers only to the number of mature rRNA molecules which will be produced from the primary transcript and ignores tRNAs that may also be present within the primary transcript.


description: Catalysis of the reaction: 2-hydroxy-7-hydroxymethylchromene-2-carboxylate = 2-hydroxy-4-hydroxymethylbenzalpyruvate.


description: The chemical reactions and pathways involving gamma-1,2,3,4,5,6-hexachlorocyclohexane (also known as Lindane), the most common form of hexachlorohexane, a halogenated organic insecticide that has been used worldwide for agriculture and public health.


tagatose-6-phosphate kinase activity

description: Catalysis of the reaction: ATP + D-tagatose 6-phosphate = ADP + D-tagatose 1,6-bisphosphate.


vitamin D4 metabolic process

description: The chemical reactions and pathways involving vitamin D4, (3S,5Z,7E)-9,10-secoergosta-5,7,10(19)-trien-3-ol.


name: glucosinolate transmembrane transporter activity

description: Enables the transfer of a glucosinolate across a membrane.


versicolorin B desaturase activity

description: Catalyzes the reaction: versicolorin B + NADPH + O2 = versicolorin A + NADP+ + 2 H2O. Uses heme-thiolate as a co-factor. Involved in the synthesis of aflatoxins in the fungus Aspergillus parasiticus.


description: Catalysis of the reaction: UDP-galactose + N-glycan = galactose-beta-1,3-N-glycan + UDP.


description: Catalysis of the reaction: [oligomeric (1->3)-beta-D-glucosyl](n) + phosphate = [(1->3)-beta-D-glucosyl](n-1) + alpha-D-glucose 1-phosphate.


name: neural crest-derived cardiac glial cell development

description: The process aimed at the progression of a neural crest-derived cardiac glial cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.


description: Catalysis of the reaction: 2,3-dihydroxybenzoate + O2 = 2-carboxy-cis,cis-muconate + 2 H+.


name: G-protein gated monoatomic ion channel activity

description: An ion channel activity that is gated by binding of a G-protein beta-gamma dimer.


regulation of ferrochelatase activity

description: Any process that modulates the frequency, rate or extent of ferrochelatase activity; catalysis of the reaction: protoporphyrin + Fe2+ = protoheme + 2 H+.


lactate catabolic process

description: The chemical reactions and pathways resulting in the breakdown of lactate.


mesoderm structural organization

description: The process that contributes to the act of creating the structural organization of the mesoderm. This process pertains to the physical shaping of a rudimentary structure.


viral tail assembly

description: The aggregation, arrangement and bonding together of a set of components to form a virus tail.


name: negative regulation of vesicle transport along microtubule

description: Any process that stops, prevents or reduces the frequency, rate or extent of vesicle transport along microtubule.


alpha-N-acetylglucosaminidase activity

description: Catalysis of the hydrolysis of terminal non-reducing N-acetyl-D-glucosamine residues in N-acetyl-alpha-D-glucosaminides.


name: chemorepulsion of branchiomotor neuron axon in neural tube

description: The process in which a branchiomotor neuron growth cone in the neural tube is directed to a specific target site in the neural tube in response to a repulsive chemical cue. Branchiomotor neurons are located in the hindbrain and innervate branchial arch-derived muscles that control jaw movements, facial expression, the larynx, and the pharynx.


neuron projection arborization

description: The process in which the anatomical structures of a neuron projection are generated and organized into branches. A neuron projection is any process extending from a neural cell, such as axons or dendrites.


name: 3,4-dihydroxy-5-polyprenylbenzoic acid O-methyltransferase activity

description: Catalysis of the reaction: 3,4-dihydroxy-5-polyprenylbenzoic acid + S-adenosyl-L-methionine = 3-methoxy-4-hydroxy-5-polyprenylbenzoic acid + S-adenosyl-L-homocysteine + H+.


name: positive regulation of sevenless signaling pathway

description: Any process that activates or increases the frequency, rate or extent of the sevenless signaling pathway.


selenocysteine catabolic process

description: The chemical reactions and pathways resulting in the breakdown of selenocysteine, an essential component of glutathione peroxidase and some other proteins.


name: response to cell size control checkpoint signaling

description: A process that occurs in response to signals generated as a result of cell size control checkpoint signaling.


name: transmembrane signaling receptor activity

description: Combining with an extracellular or intracellular signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity or state as part of signal transduction.


name: transcription elongation by mitochondrial RNA polymerase

description: The extension of an RNA molecule after transcription initiation and promoter clearance at mitochondrial promoter by the addition of ribonucleotides catalyzed by a mitchondrial RNA polymerase.


name: symbiont-mediated occlusion of host xylem

description: The process in which an organism reduces the flow of fluid within the host xylem, the tissue in plants that carries water and nutrients up from the roots to the shoot and leaves. The host is defined as the larger of the organisms involved in a symbiotic interaction.


name: symbiont-mediated suppression of host gene expression

description: A process in which a symbiont inhibits or disrupts expression of genes in its host. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Some protein processing events may be included when they are required to form an active form of a product from an inactive precursor form. The host is defined as the larger of the organisms involved in a symbiotic interaction.


chloromuconate cycloisomerase activity

description: Catalysis of the reaction: 2-chloro-2,5-dihydro-5-oxofuran-2-acetate = 3-chloro-cis,cis-muconate.


name: evasion by virus of host natural killer cell activity

description: Any process by which a virus avoids the effects mediated by the host organism's natural killer (NK) cells.


name: positive regulation of ecdysteroid secretion

description: Any process that activates or increases the frequency, rate or extent of the regulated release of ecdysteroid.


name: positive regulation of the force of heart contraction by neuronal epinephrine-norepinephrine

description: Any process that increases the force with which the cardiac muscles of the heart pump blood through the circulatory system as a result of the presence of epinephrine or norepinephrine released from the nerve endings.


description: Catalysis of the reaction: 4-hydroxybutyraldehyde + H2O = 2 H+ + 2 e- + 4-hydroxybutanoate.


name: temperature compensation of the circadian clock

description: The process in which the circadian clock maintains robust and accurate timing over a broad range of physiological temperatures. The circadian clock is an endogenous 24-h timer found in most eukaryotes and in photosynthetic bacteria. The clock drives rhythms in the physiology, biochemistry, and metabolism of the organisms.


name: negative regulation of interleukin-18-mediated signaling pathway

description: Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-18-mediated signaling pathway.


name: positive regulation of retinal cell programmed cell death

description: Any process that activates or increases the frequency, rate or extent of programmed cell death that occurs in the retina.


name: malate:sodium symporter activity

description: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: malate(out) + Na+(out) = malate(in) + Na+(in).


name: epiblast cell-extraembryonic ectoderm cell signaling involved in anterior/posterior axis specification

description: Any process that mediates the transfer of information from an epiblast cell to an extraembryonic ectoderm cell that contributes to the specification of the anterior/posterior axis.


description: Catalysis of the reaction: alpha-L-arabinose 1-phosphate + UTP = UDP-L-arabinose + diphosphate.


ERBB2-ERBB4 signaling pathway

description: The series of molecular signals initiated by binding of a ligand to a ERBB4 receptor on the surface of a cell, followed by transmission of the signal by a heterodimeric complex of ERBB2 and ERBB4. ERBB2, which does not bind any known ligand, is activated through formation of a heterodimer with another ligand-activated ERBB family member such as ERBB4.


description: Catalysis of the reaction: 4-coumaryl-CoA + 3-oxooctanoyl-CoA + H2O = 4-coumaroylhexanoylmethane + 2 coenzyme A + carbon dioxide.


name: nuclear polyadenylation-dependent snRNA catabolic process

description: The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of a small nuclear RNA (snRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target snRNA.


name: negative regulation of male pigmentation

description: Any process that stops, prevents, or reduces the frequency, rate or extent of establishment of a pattern of pigment in males.


name: protein localization to astral microtubule

description: A process in which a protein is transported to, or maintained in, a location within an astral microtubule.


siRNA transcription

description: The transcription of a small interfering RNA from an RNA template.


peptidyl-lysine glutarylation

description: The glutarylation of a lysine residue in a protein.


adaxial/abaxial pattern specification

description: The regionalization process in which differences in cell differentiation along the adaxial/abaxial are generated. Adaxial refers to being situated toward an axis of an anatomical structure. Abaxial refers to being situated away from an axis of an anatomical structure.


name: all-trans retinoic acid 18-hydroxylase activity

description: Catalysis of the reaction: all-trans-retinoate + O2 + reduced [NADPH--hemoprotein reductase] = all-trans-18-hydroxyretinoate + H+ + H2O + oxidized [NADPH--hemoprotein reductase].


name: negative regulation of cell-glial cell adhesion involved in cerebral cortex lamination

description: The process that results in the release of migrating cells from their interaction with radial glial cells as a component of the process of cerebral cortex glial-mediated radial cell migration.


name: dorsal/ventral lineage restriction, imaginal disc

description: Formation and/or maintenance of a lineage boundary between dorsal and ventral compartments that cells cannot cross, thus separating the populations of cells in each compartment.


name: L-tyrosine biosynthetic process from chorismate via L-arogenate

description: The chemical reactions and pathways resulting in the formation of L-tyrosine from other compounds, including chorismate, via the intermediate L-arogenate.


ureide biosynthetic process

description: The chemical reactions and pathways resulting in the formation of ureide, the organic form of nitrogen in nitrogen fixing and transporting plants, from IMP, which is synthesized de novo during nitrogen fixation by roots.


name: positive regulation of tyramine signaling pathway

description: Any process that activates or increases the frequency, rate or extent of tyramine signaling pathway.


name: mitotic DNA replication lagging strand elongation

description: Any lagging strand elongation that is involved in mitotic cell cycle DNA replication.


description: The chemical reactions and pathways resulting in the formation of sophorosyloxydocosanoate, 13-sophorosyloxydocosanoate 6',6''-diacetate.


name: ABC-type carbohydrate transporter activity

description: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O = ADP + phosphate, to directly drive the transport of carbohydrates across a membrane.


name: negative regulation of chromosome attachment to the nuclear envelope

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the chromosome attachment to the nuclear envelope.


name: ionotropic salty taste receptor activity

description: Enables the transmembrane transfer of an ion by a channel that opens when a soluble salty compound has been bound by the channel complex or one of its constituent parts.


allantoin racemase activity

description: Catalysis of the reaction: (S)-(+)-allantoin = (R)-(-)-allantoin.


name: negative regulation of innate immunity memory response

description: Any process that stops, prevents or reduces the frequency, rate or extent of innate immunity memory response.


name: positive regulation of nitric oxide mediated signal transduction

description: Any process that increases the rate, frequency or extent of nitric oxide mediated signal transduction. Nitric oxide mediated signal transduction is The series of molecular signals mediated by the detection of nitric oxide (NO).


peptidyl-threonine acetylation

description: The acetylation of peptidyl-threonine.


peptide butyryltransferase activity

description: Catalysis of the reaction: butyryl-CoA + lysine in peptide = CoA + N-butyryl-lysine-peptide.


description: Catalysis of the hydrolysis of alpha-(1->4)-D-glucosidic linkage in 4-alpha-D-{(1->4)-alpha-D-glucanosyl}n trehalose to yield trehalose and alpha-(1->4)-D-glucan.


methylselenol demethylase activity

description: Catalysis of the reaction: methylselenol + H2O => H2Se + CH3OH.


pectoral fin development

description: The process whose specific outcome is the progression of the pectoral fin over time, from its formation to the mature structure.


determination of affect

description: Any process in which an emotional response is associated with a particular sensory stimulation.


name: UDP-glucose: N-methylanthranilate glucosyltransferase activity

description: Catalysis of the reaction: N-methylanthranilate + UDP-alpha-D-glucose = N-methylanthraniloyl-beta-D-glucopyranose + UDP.


homeostasis of number of meristem cells

description: Any biological process involved in the maintenance of the steady-state number of cells within a population of cells in the meristem.


name: negative regulation of glucose mediated signaling pathway

description: Any process that stops, prevents or reduces the frequency, rate or extent of glucose mediated signaling pathway.


thiamine oxidase activity

description: Catalysis of the reaction: thiamine + 2 O2 = thiamine acetic acid + 2 H2O2.


name: regulation of response to G2 DNA damage checkpoint signaling

description: Any process that modulates the frequency, rate or extent of response to G2 DNA damage checkpoint signaling.


name: regulation of acetylcholine-gated cation channel activity

description: Any process that modulates the frequency, rate or extent of acetylcholine-gated cation channel activity.


name: regulation of iodide transmembrane transport

description: Any process that modulates the frequency, rate or extent of iodide transmembrane transport.


description: Catalysis of the reaction: S-adenosyl-L-methionine + xanthotoxol = S-adenosyl-L-homocysteine + xanthotoxin. Xanthotoxol is also known as 8-hydroxyfuranocoumarin and xanthotoxin as 8-methoxyfuranocoumarin.


description: Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate(3-) = valerena-4,7(11)-diene + diphosphoric acid.


style development

description: The process whose specific outcome is the progression of the style over time, from its formation to the mature structure. The style is an elongated part of a carpel, or group of fused carpels, and it lies between the ovary and the stigma.


alpha-D-glucan binding

description: Binding to alpha-D-glucan.


name: branched-chain amino acid catabolic process to alcohol via Ehrlich pathway

description: The chemical reactions and pathways involving the catabolism of branched chain amino acids to produce branched chain alcohols with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. When a branched chain family amino acid, leucine, isoleucine, or valine, is used as the substrate, 3-methylbutanol, 2-methylbutanol, or 2-methylpropanol, respectively, is produced. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of alcohols, often collectively referred to as fusel alcohols. Depending on the redox state of the cells, carboxylic acid derivatives may be produced instead of alcohols.


description: Catalysis of the reaction: apigenin 7-O-beta-D-glucoside + UDP-alpha-D-glucose = apigenin-7-O-gentiobioside + UDP + H+.


name: positive regulation of sulfite transport

description: Any process that activates or increases the frequency, rate or extent of sulfite transport.


type I hypersensitivity

description: An inflammatory response driven by antigen recognition by antibodies bound to Fc receptors on mast cells or basophils, occurring within minutes after exposure of a sensitized individual to the antigen, and leading to the release of a variety of inflammatory mediators such as histamines.


name: maintenance of protein complex location in cytoplasm

description: Any process in which a protein complex is maintained in a specific location within the cytoplasm and is prevented from moving elsewhere.


tocopherol cyclase activity

description: Catalysis of the reactions: delta-tocopherol = 2-methyl-6-phytyl-1,4-benzene-1,4-diol, gamma-tocopherol = 2,3-dimethyl-6-phytylbenzene-1,4-diol. delta-tocotrienol = 6-geranylgeranyl-2-methylbenzene-1,4-diol gamma-tocotrienol, and = 6-geranylgeranyl-2,3-dimethylbenzene-1,4-diol.


L-arabinose isomerase activity

description: Catalysis of the reaction: L-arabinose = L-ribulose.


name: positive regulation of Fas signaling pathway

description: Any process that activates or increases the frequency, rate or extent of Fas signaling pathway.


citrazinate dehydrogenase activity

description: Catalysis of the reaction: citrazinate + H2O = 2,3,6-trihydroxyisonicotinate + 2 H+ + 2 e-.


description: Catalysis of the reaction: indoxyl + UDP-D-glucose = H+ + indican + UDP.


name: detection of electrical stimulus involved in regulation of muscle adaptation

description: The series of events by which an electrical stimulus is received and converted into a molecular signal. This occurs as part of the regulation of muscle adaptation.


parthenolide synthase activity

description: Catalysis of the reaction: costunolide + NADPH + O2 + H+ = parthenolide + NADP(3-) + H2O.


corticotropin receptor activity

description: Combining with corticotropin to initiate a change in cell activity.


description: Catalysis of the reaction: N,N'-diacetyl-alpha-D-bacillosaminyl-diphospho-tri-trans,hepta-cis-undecaprenol + UDP-N-acetyl-D-galactosamine = N-acetyl-D-galactosaminyl-alpha-(1->3)-N,N'-diacetyl-alpha-D-bacillosaminyl-diphospho-tri-trans,hepta-cis-undecaprenol + UDP + H+.


description: Catalysis of the reaction: hydroxymethylmethylsilanediol + O2 + 2 H+ + 2 e- = formylmethylsilanediol + 2 H2O.


description: Catalysis of the reaction: 1-(5-phospho-D-ribosyl)-ATP + H2O = 1-(5-phosphonatoribosyl)-5'-AMP + diphosphate + H+.


rhombomere 5 structural organization

description: The process that contributes to creating the structural organization of rhombomere 5. This process pertains to the physical shaping of a rudimentary structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.


name: prephenate dehydrogenase (NAD+) activity

description: Catalysis of the reaction: NAD+ + prephenate = (4-hydroxyphenyl)pyruvate + CO2 + NADH.


taurine dehydrogenase activity

description: Catalysis of the reaction: A + H2O + taurine = AH(2) + NH4 + sulfoacetaldehyde.


description: Catalysis of the reaction: UDP-galactose + glycoprotein-alpha-L-fucosyl-(1,2)-D-galactose = UDP + glycoprotein-alpha-D-galactosyl-(1,3)-(alpha-L-fucosyl-(1,2))-D-galactose.


description: Catalysis of the reaction: L-tyrosine + pyruvate = (4-hydroxyphenyl)pyruvate + L-alanine.


name: positive regulation of nigerotriose transport

description: Any process that activates or increases the frequency, rate or extent of nigerotriose transport.


steryl-sulfatase activity

description: Catalysis of the reaction: 3-beta-hydroxyandrost-5-en-17-one 3-sulfate + H2O = 3-beta-hydroxyandrost-5-en-17-one + sulfate.


name: peptidyl-glycine cholesteryl ester biosynthesis from peptidyl-glycine

description: The synthesis of peptidyl-glycine cholest-5-en-3-beta-ol ester at the carboxy-terminus of autolytically cleaved proteins.


cellular response to cation stress

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of cation stress, an increase or decrease in the concentration of positively charged ions in the environment.


3,4-dihydroxybenzoate metabolic process

description: The chemical reactions and pathways involving protocatechuate, the anion of protocatechuic acid (3,4-dihydroxybenzoic acid).


viral DNA genome replication

description: The replication of a viral DNA genome.


name: malonate semialdehyde decarboxylase activity

description: Catalysis of the reaction: malonate semialdehyde + H+ = acetaldehyde + CO2.


name: site-specific DNA-methyltransferase (adenine-specific) activity

description: Catalysis of the reaction: S-adenosyl-L-methionine + DNA adenine = S-adenosyl-L-homocysteine + DNA 6-methylaminopurine.


description: Catalysis of the reaction: H2O + NAD+ + 2-aminomuconate semialdehyde = NADH + 2-amino-muconate.


description: Catalysis of the reaction: a phosphatidylethanolamine + a sterol = a sterol ester + a lysophosphatidylethanolamine.


name: symbiont-mediated perturbation of host intracellular transport

description: A process in which a symbiont alters or subverts the directed movement of substances within the cell of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.


name: regulation of cellotriose catabolic process

description: Any process that modulates the frequency, rate or extent of cellotriose catabolic process.


name: mesenchymal stem cell proliferation involved in nephron morphogenesis

description: The multiplication or reproduction of mesenchymal stem cells, resulting in the expansion of a stem cell population, that contributes to the shaping of a nephron.


name: vinyl chloride reductive dehalogenase activity

description: Catalysis of the reaction: vinyl chloride + 2 H+ + 2 e- = HCl + ethene.


description: The chemical reactions and pathways involving beta-D-galactofuranose.


structural constituent of postsynapse

description: The action of a molecule that contributes to the structural integrity of a postsynapse.


name: acinar cell differentiation involved in salivary gland development

description: The process in which a relatively unspecialized cell acquires specialized structural and/or functional features that characterize an acinar cell of the salivary gland. Acinar cells are protein-secreting cells in the gland.


plastid DNA metabolic process

description: The chemical reactions and pathways involving plastid DNA.


name: establishment of protein localization to postsynaptic membrane

description: The directed movement of a protein to a specific location in a postsynaptic membrane.


name: cyanidin 3-O-p-coumaroylglucoside 2-O''-xylosyltransferase activity

description: Catalysis of the reaction: cyanidin 3-O-(6-O-(E)-4-coumaroyl-beta-D-glucoside) + UDP-alpha-D-xylose = cyanidin 3-O-[2''-O-xylosyl) 6''-O-(p-coumaroyl) glucoside + UDP + H+.


chitosanase activity

description: Catalysis of the endohydrolysis of beta-1,4-linkages between N-acetyl-D-glucosamine and D-glucosamine residues in a partly acetylated chitosan.


description: Catalysis of the reaction: 2 1-O-sinapoyl-beta-D-glucose = 1,2-di-O-sinapoyl-beta-D-glucose + D-glucose.


11-oxo-beta-amyrin metabolic process

description: The chemical reactions and pathways involving 11-oxo-beta-amyrin.


name: dorsal spinal cord interneuron anterior axon guidance

description: The process in which the migration of an axon growth cone of a dorsal spinal cord interneuron is directed to a specific target site in the anterior direction along the anterior-posterior body axis in response to a combination of attractive and repulsive cues. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism.


butanediol metabolic process

description: The chemical reactions and pathways involving butanediol; the biologically relevant isomer is 2,3-butanediol, CH3CH(OH)CH(OH)CH3.


name: negative regulation of syringal lignin catabolic process

description: Any process that stops, prevents or reduces the frequency, rate or extent of syringal lignin catabolic process.


name: regulation of pre-tubular aggregate formation by cell-cell signaling

description: Any process that mediates the transfer of information from one cell to another that modulates the rate, frequency, or extent of pre-tubular aggregate formation. Pre-tubular aggregate formation is the cell adhesion process in which mesenchymal cells adhere to one another in the initial stages of the formation of the pre-tubular aggregate, the earliest recognizable structure of the kidney.


response to alkyl hydroperoxide

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alkyl hydroperoxide stimulus. Alkyl hydroperoxides are monosubstitution products of hydrogen peroxide, HOOH, where the substituent is an alkyl group.


allophanate hydrolase activity

description: Catalysis of the reaction: H2O + 3 H+ + urea-1-carboxylate = 2 CO2 + 2 NH4.


name: positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator

description: Any process that activates or increases the frequency, rate or extent of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator.


description: Catalysis of the reaction: hydroxidodioxidosulfidosulfate + a reduced thioredoxin = sulfite + hydrogen sulfide + H+ + an oxidized thioredoxin.


name: vesicle targeting, plasma membrane to endosome

description: The process in which vesicles formed at the plasma membrane are directed to specific destinations in endosome membranes, mediated by molecules at the vesicle membrane and target membrane surfaces.


hexitol catabolic process

description: The chemical reactions and pathways resulting in the breakdown of hexitols, any alditol with a chain of six carbon atoms in the molecule.


description: Catalysis of the reaction: CoA + substrate-serine = adenosine 3',5'-bisphosphate + substrate-serine-4'-phosphopantetheine. The transfer of the 4'-phosphopantetheine (Ppant) co-factor from coenzyme A to the hydroxyl side chain of the serine residue of acyl- or peptidyl-carrier protein (ACP or PCP) to convert them from the apo to the holo form.


serine 2-dehydrogenase activity

description: Catalysis of the reaction: L-serine + H2O + NAD+ = 3-hydroxypyruvate + NH3 + NADH.


mitochondrial tRNA 5'-end processing

description: The process in which the 5' end of a pre-tRNA molecule is converted to that of a mature tRNA in the mitochondrion.


name: peptide cross-linking via 2-(S-L-cysteinyl)-D-allo-threonine

description: The post-translational cross-linking of a cysteine residue to an L-threonine residue to form 2-(S-L-cysteinyl)-D-allo-threonine.


name: negative regulation of cellular response to nitrogen starvation

description: Any process that stops, prevents, or reduces the frequency, rate or extent of a cellular response to nitrogen starvation.


gastric mucosal blood circulation

description: The flow of blood through the gastric mucosa of an animal, enabling the transport of nutrients and the removal of waste products.


macrolide 2'-kinase activity

description: Catalysis of the reaction: ATP + oleandomycin = ADP + 2 H+ + oleandomycin 2'-O-phosphate.


description: Catalysis of the reaction: H2O + maltose 6'-phosphate = D-glucose + D-glucose 6-phosphate.


2-aminohexanoate transaminase activity

description: Catalysis of the reaction: L-2-aminohexanoate + 2-oxoglutarate = 2-oxohexanoate + L-glutamate.


name: 23S rRNA (guanine(748)-N(1))-methyltransferase activity

description: Catalysis of the reaction: S-adenosyl-L-methionine + guanine(748) in 23S rRNA = N(1)-methylguanine(748) in 23S rRNA + S-adenosyl-L-homocysteine.


isoleucine biosynthetic process

description: The chemical reactions and pathways resulting in the formation of isoleucine, (2R*,3R*)-2-amino-3-methylpentanoic acid.


description: Catalysis of the reaction: UDP-alpha-D-glucose + 8-methylthiooctylhydroximate = H+ + 7-methylthioheptyldesulfoglucosinolate + UDP.


GCU codon-amino acid adaptor activity

description: A triplet codon-amino acid adaptor activity that recognizes a GCU codon.


ecdysone binding

description: Binding to 20-hydroxyecdysone (ecdysone). Ecdysone is an ecdysteroid produced by the prothoracic glands of immature insects and the ovaries of adult females, which stimulates growth and molting.


pyruvate catabolic process

description: The chemical reactions and pathways resulting in the breakdown of pyruvate, 2-oxopropanoate.


2-alkyn-1-ol dehydrogenase activity

description: Catalysis of the reaction: 2-butyne-1,4-diol + NAD+ = 4-hydroxy-2-butynal + H+ + NADH.


name: positive regulation of pancreatic A cell differentiation

description: Any process that activates or increases the frequency, rate or extent of pancreatic A cell differentiation.


leukotriene D4 metabolic process

description: The chemical reactions and pathways involving leukotriene D4.


IgA receptor activity

description: Combining with an immunoglobulin of an IgA isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


type IV pilus-dependent motility

description: Any process involved in the controlled movement of a bacterial cell which is dependent on the presence of type IV pili. Includes social gliding motility and twitching motility.


2-oxobutyrate catabolic process

description: The chemical reactions and pathways resulting in the breakdown of 2-oxobutyrate, the anion of the organic acid 2-oxobutyric acid, which contains a ketone group on carbon 2.


alternative respiration

description: Alternative respiration pathway consumes oxygen, oxidizes NADH to NAD+ and generates water. During electron flow, proton motive force is diminished resulting in fewer molecules of ATP compared to cytochrome pathway. The pathway is found in plants, algae and some protozoa.


cellular response to triterpenoid

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a triterpenoid stimulus.


name: germarium-derived female germ-line cyst encapsulation

description: Formation of a single follicular epithelium around the germ-line derived cells of a cyst formed in the germarium. An example of this process is found in Drosophila melanogaster.


detection of pheromone

description: The series of events in which a pheromone stimulus is received by a cell and converted into a molecular signal.


bixin aldehyde dehydrogenase activity

description: Catalysis of the reaction: bixin aldehyde + O2 + NAD = norbixin + NADH + H+.


name: positive regulation of heart rate by circulating epinephrine

description: The process in which the secretion of epinephrine into the bloodstream increases the rate of heart muscle contraction.


name: negative regulation of sorocarp spore cell differentiation

description: Any process that stops, prevents or reduces the frequency, rate or extent of sorocarp spore cell differentiation.


name: D-lactate dehydrogenase (quinone) activity

description: Catalysis of the reaction: (R)-lactate + an ubiquinone = pyruvate + an ubiquinol.


description: Catalysis of the reaction: a cytidine in mRNA + S-adenosyl-L-methionine = a 5-methylcytidine in mRNA + H+ + S-adenosyl-L-homocysteine.


name: intermediate-density lipoprotein particle binding

description: Binding to a intermediate-density lipoprotein particle, a triglyceride-rich lipoprotein particle that typically contains APOB100, APOE and APOCs and has a density of 1.006-1.019 g/ml and a diameter of between 25-30 nm.


polyphosphate biosynthetic process

description: The chemical reactions and pathways resulting in the formation of a polyphosphate, the anion or salt of polyphosphoric acid.


cytidylate cyclase activity

description: Catalysis of the reaction: CTP = 3',5'-cyclic CMP + diphosphate + H+.


4-nitrophenol 2-monooxygenase activity

description: Catalysis of the reaction: 4-nitrophenol + H+ + NADH + O2 = 4-nitrocatechol + H2O + NAD+.


name: negative regulation of appressorium formation

description: Any process that stops, prevents, or reduces the frequency, rate or extent of symbiont appressorium formation.


arabinan metabolic process

description: The chemical reactions and pathways involving arabinan, a polysaccharide composed of arabinose residues.


RITS complex localization

description: Any process in which a RITS complex is transported to, or maintained in, a specific location.


name: protein localization to polar microtubule

description: A process in which a protein is transported to, or maintained in, a location within a polar microtubule.


name: stomach pylorus smooth muscle contraction

description: A process in which force is generated within gastric smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the most distal part of the stomach.


name: histone H2AK119 ubiquitin ligase activity

description: Catalysis of the transfer of a ubiquitin molecule to histone 2A at the lysine-119 residue.


name: trans-synaptic signaling by carbon monoxide

description: Cell-cell signaling between presynapse and postsynapse mediated by carbon monoxide.


isopentenyl phosphate kinase activity

description: Catalysis of the reaction: isopentenyl phosphate(2-) + ATP(4-) = isopentenyl diphosphate(3-) + ADP(3-).


XMP biosynthetic process

description: The chemical reactions and pathways resulting in the formation of XMP, xanthosine monophosphate.


progression of neural tube closure

description: The process in which the neural folds are fused extending from the initial closure points.


amylin receptor activity

description: Combining with amylin to initiate a change in cell activity.


terminal region determination

description: Specification of the terminal regions (the two non-segmented ends) of the embryo by the gap genes; exemplified in insects by the actions of huckebein and tailless gene products.


name: regulation of secondary cell wall biogenesis

description: Any process that modulates the frequency, rate or extent of secondary cell wall biogenesis.


interleukin-7 production

description: The appearance of interleukin-7 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


name: regulation of bundle of His cell action potential

description: Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a cardiac muscle cell of the bundle of His. This typically occurs via modulation of the activity or expression of voltage-gated ion channels.


name: regulation of lipid transport across blood-brain barrier

description: Any process that modulates the frequency, rate or extent of lipid transport across blood-brain barrier.


deoxycytidine biosynthetic process

description: The chemical reactions and pathways resulting in the formation of deoxycytidine, 2-deoxyribosylcytosine, one of the four major nucleosides of DNA.


regulation of blood vessel branching

description: Any process that modulates the frequency, rate or extent of blood vessel branching.


description: Catalysis of the reaction: acetyl-CoA + an N-hydroxyarylamine = CoA + an N-acetoxyarylamine.


ribitol metabolic process

description: The chemical reactions and pathways involving ribitol, a pentitol derived formally by reduction of the -CHO group of either D- or L-ribose. It occurs free in some plants and is a component of riboflavin.


description: Catalysis of the reaction: beta-carotene + O2 = 10'-apo-beta-carotenal + beta-ionone.


description: Catalysis of the reaction: 5-deoxy-D-glucuronate = 5-dehydro-2-deoxy-D-gluconate.


lysine racemase activity

description: Catalysis of the reaction: L-lysine = D-lysine.


name: apical constriction involved in ventral furrow formation

description: The actin-mediated process that results in contraction of the apical end of a polarized columnar epithelial cell, contributing to formation of a ventral indentation (furrow) from the blastoderm epithelium, which is internalized to form a tube in the interior of the embryo, marking the start of gastrulation.


11-oxo-beta-amyrin 30-oxidase activity

description: Catalysis of the reaction: 11-oxo-beta-amyrin + 3 NADPH + 3 O2 + 2 H+ = glycyrrhetinic acid + 3 NADP + 4 H2O.


name: epicardium-derived cell migration to the myocardium

description: The orderly movement of a cell that have undergone an epithelial to mesenchymal transition from the epicardium into the myocardium.


5-dehydro-2-deoxygluconokinase activity

description: Catalysis of the reaction: ATP + 5-dehydro-2-deoxy-D-gluconate = ADP + 6-phospho-5-dehydro-2-deoxy-D-gluconate.


name: putrescine biosynthetic process from arginine, using agmatinase

description: The chemical reactions and pathways resulting in the formation of putrescine, 1,4-diaminobutane, from other compounds, including arginine; in this pathway, arginine is converted to agmatine, and agmatine is converted to putrescine in a single enzymatic step.


description: The chemical reactions and pathways resulting in the breakdown of beta-D-galactofuranose.


name: mesonephric interstitial fibroblast fate commitment

description: The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesonephric interstitial fibroblast.


neural crest cell fate specification

description: The process in which a cell becomes capable of differentiating autonomously into a neural crest cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.


name: positive regulation of nitrogen utilization

description: Any process that activates or increases the frequency, rate or extent of nitrogen utilization.


name: positive regulation of endodermal cell differentiation

description: Any process that activates or increases the frequency, rate or extent of endodermal cell differentiation.


glutamate synthase (NADH) activity

description: Catalysis of the reaction: 2 L-glutamate + NAD+ = 2-oxoglutarate + L-glutamine + H+ + NADH.


name: tetrapyrrole biosynthetic process from glutamate

description: The chemical reactions and pathways leading to the formation of tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next, from other compounds, including L-glutamate.


name: planar cell polarity pathway involved in cardiac muscle cell fate commitment

description: The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via effectors other than beta-catenin and contributing to a cardioblast being committed to a cardiac muscle cell fate.


description: Catalysis of the hydrolysis of (1->6)-alpha-D-glucosidic linkages in dextrans, to remove successive isomaltotriose units from the non-reducing ends of the chains.


name: thioacetamide S-oxide S-oxygenase activity

description: Catalysis of the reaction: thioacetamide S-oxide + O2 + 2 H+ + 2 e- = thioacetamide S,S-dioxide + H2O.


R2/R5 cell differentiation

description: The process in which relatively unspecialized cells acquire the specialized features of R2 and R5 photoreceptors. An example of this process is found in Drosophila melanogaster.


apiose 1-reductase activity

description: Catalysis of the reaction: D-apiitol + NAD+ = D-apiose + H+ + NADH.


name: maturation of LSU-rRNA from tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, 2S rRNA, LSU-rRNA)

description: Any process involved in the maturation of a precursor Large SubUnit (LSU) ribosomal RNA (rRNA) molecule into a mature LSU-rRNA molecule from the pre-rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, 5.8 S rRNA, 2S rRNA, and Large Subunit (LSU) in that order from 5' to 3' along the primary transcript.


phosphatidylserine transfer activity

description: Removes phosphatidylserine from the outer leaflet of a donor membrane, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to the outer leaflet of an acceptor membrane.


peptide histaminyltransferase activity

description: Catalysis of the reaction: histamine + L-glutaminyl-[protein] = 5-histaminyl-L-glutamyl-[protein].


phosphatidylserine floppase activity

description: Catalysis of the movement of phosphatidylserine from the cytosolic to the exoplasmic leaftlet of a membrane, using energy from the hydrolysis of ATP.


name: symbiont-mediated activation of host G protein-coupled receptor signal transduction

description: A process in which a symbiont initiates, promotes, or enhances a G protein-coupled receptor signal transduction pathway in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.


thromboxane receptor activity

description: Combining with a thromboxane (TXA) to initiate a change in cell activity.


name: histidine catabolic process to hydantoin-5-propionate

description: The chemical reactions and pathways resulting in the breakdown of histidine into other compounds, including hydantoin-5-propionate.


description: The chemical reactions and pathways resulting in the formation of beta-1,2-linked oligomannosides, which are found in fungal cell wall phosphopeptidomannan and phospholipomannan.


name: pyridoxine transmembrane transporter activity

description: Enables the transfer of pyridoxine from one side of a membrane to the other. Pyridoxine, 2-methyl-3-hydroxy-4,5-bis(hydroxymethyl)pyridine, is one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate.


channel-forming ionophore activity

description: Enables transport of a solute across a membrane. This kind of transporter interacts much more weakly with the solute than the carrier does. It is an aqueous pore that extends across the membrane. It may change from closed to open and back. It transports faster than a carrier. It is always passive.


description: Catalysis of the reaction: 4'-hydroxyacetophenone + H+ + NADPH + O2 = 4-hydroxyphenyl acetate + H2O + NADP+.


pineal gland development

description: The progression of the pineal gland over time from its initial formation until its mature state. The pineal gland is an endocrine gland that secretes melatonin and is involved in circadian rhythms.


structural constituent of virion

description: The action of a molecule that contributes to the structural integrity of a virion.


galactitol metabolic process

description: The chemical reactions and pathways involving galactitol, the hexitol derived by the reduction of the aldehyde group of either D- or L-galactose.


description: Catalysis of the reaction: rhamnetin + S-adenosyl-L-methionine = ombuin + S-adenosyl-L-homocysteine + H+.


name: L-lysine catabolic process to glutarate, by acetylation

description: The chemical reactions and pathways resulting in the breakdown of L-lysine into other compounds, including glutarate, by acetylation.


(S)-canadine synthase activity

description: Catalysis of the reaction: (S)-tetrahydrocolumbamine + [reduced NADPH--hemoprotein reductase] + O2 -> (S)-canadine + [oxidized NADPH--hemoprotein reductase] + 2 H2O.


description: Catalysis of the reaction: A [sulfatase]-L-cysteine + O2 + 2 a thiol = a [sulfatase]-3-oxo-L-alanine + hydrogen sulfide + a disulfide + H2O.


photoreactive repair

description: The repair of UV-induced T-T, C-T and C-C dimers by directly reversing the damage to restore the original pyrimidines.


name: positive regulation of relaxation of cardiac muscle

description: Any process that activates or increases the frequency, rate or extent of relaxation of cardiac muscle.


actinorhodin biosynthetic process

description: The chemical reactions and pathways resulting in the formation of actinorhodin.


phosphoribulokinase activity

description: Catalysis of the reaction: D-ribulose 5-phosphate + ATP = D-ribulose 1,5-bisphosphate + ADP + 2 H+.


name: malate transmembrane transporter activity

description: Enables the transfer of malate from one side of a membrane to the other. Malate is a chiral hydroxydicarboxylic acid, hydroxybutanedioic acid. The (+) enantiomer is an important intermediate in metabolism as a component of both the TCA cycle and the glyoxylate cycle.


description: Catalysis of the reaction: S-methyl-L-methionine + L-homocysteine = 2 L-methionine + H+.


name: regulation of cleistothecium development

description: Any process that modulates the frequency, rate or extent of cleistothecium development, a process that leads to the formation of a cleistothecium. The cleistothecium is a closed sexual fruiting body that contains ascospores in linear asci, characteristic of some filamentous Ascomycete fungi such as members of the genera Aspergillus and Emericella.


CAAX-box protein modification

description: The covalent alteration of one or more amino acid residues within the CAAX box region of CAAX box proteins.


name: genital disc anterior/posterior pattern formation

description: The establishment, maintenance and elaboration of the anterior/posterior axis of the genital disc. An anterior and posterior compartment form in each of the three genital disc primoridia (the female genital disc primordium, the male genital disc primordium and the anal primordium).


tensidol B metabolic process

description: The chemical reactions and pathways involving tensidol B.


name: anterior mRNA localization involved in anterior/posterior axis specification

description: Any process in which a mRNA is transported to, and maintained in the anterior portion of the oocyte and/or syncytial embryo contributing to the specification of the anterior/posterior axis.


aerotaxis

description: The directed movement of a motile cell or organism in response to environmental oxygen.


name: lignostilbene alpha beta-dioxygenase activity

description: Catalysis of the reaction: 1,2-bis(4-hydroxy-3-methoxyphenyl)ethylene + O2 = 2 vanillin.


name: alcohol dehydrogenase (cytochrome c(L)) activity

description: Catalysis of the reaction: 2 [Fe(III)cytochrome cL] + a primary alcohol = 2 [Fe(II)cytochrome cL] + an aldehyde + 2 H+.


name: 1,5-anhydro-D-fructose reductase (1,5-anhydro-D-mannitol-forming) activity

description: Catalysis of the reaction: 1,5-anhydro-D-mannitol + NADP+ = 1,5-anhydro-D-fructose + H+ + NADPH.


name: hydroxymate-containing siderophore biosynthetic process

description: The chemical reactions and pathways resulting in the formation of a siderophore from other compounds, including hydroxamic acid. Hydroxamate is one of the three major chemical groups incorporated into siderophore structures with catechol and a-hydroxycarboxylate, each having a high selectivity for iron(3+).


name: positive regulation of compound eye photoreceptor development

description: Any process that activates or increases the frequency, rate or extent of compound eye photoreceptor development.


anthocyanidin reductase activity

description: Catalysis of the reaction: a flavan-3-ol + 2 NAD(P)+ = an anthocyanidin + 2 NAD(P)H + H+.


dTTP catabolic process

description: The chemical reactions and pathways resulting in the breakdown of dTTP, deoxyribosylthymine triphosphate.


name: cyclic pyranopterin monophosphate synthase activity

description: Catalysis of the reaction: (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate = cyclic pyranopterin phosphate + diphosphate.


cytokinin dehydrogenase activity

description: Catalysis of the reaction: N6-dimethylallyladenine + acceptor + H2O = adenine + 3-methylbut-2-enal + reduced electron acceptor.


penicillin amidase activity

description: Catalysis of the reaction: penicillin + H2O = a carboxylate + 6-aminopenicillanate.


snoRNP binding

description: Binding to a small nucleolar ribonucleoprotein particle.


name: positive regulation of multicellular organismal process

description: Any process that activates or increases the frequency, rate or extent of an organismal process, any of the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs.


chrysobactin metabolic process

description: The chemical reactions and pathways involving the siderophore chrysobactin (alpha-N-(2,3-dihydroxybenzoyl)-D-lysyl-L-serine).


name: regulation of induction of conjugation upon nitrogen starvation

description: Any process that modulates the frequency of induction of conjugation upon nitrogen starvation, the process in which a cell initiates conjugation with cellular fusion upon nitrogen starvation.


mesonephric nephron tubule formation

description: The developmental process pertaining to the initial formation of a mesonephric nephron tubule from unspecified parts. A mesonephric nephron tubule is an epithelial tube that is part of a nephron in the mesonephros.


name: protein-RNA covalent cross-linking repair

description: A process that rescues stalled ribosomes by removing the covalent cross-link between RNA and a protein.


name: negative regulation of heart rate in another organism

description: Any process that stops, prevents or reduces the frequency of heart contraction of another organism.


regulation of rRNA catabolic process

description: Any process that modulates the frequency, rate or extent of rRNA catabolic process.


ent-kaurene oxidation to kaurenoic acid

description: The three successive oxidations of the 4-methyl group of ent-kaurene to form ent-kaur-16-en-19-oate, kaurenoic acid. This process may be carried out entirely by the enzyme ent-kaurene oxidase.


name: methanopterin-containing compound biosynthetic process

description: The chemical reactions and pathways resulting in the formation of a methanopterin.


name: formate dehydrogenase (coenzyme F420) activity

description: Catalysis of the reaction: formate + coenzyme F420 = CO2 + reduced coenzyme F420.


name: 1-18:1-2-16:0-phosphatidylglycerol omega-6 desaturase activity

description: Catalysis of the reaction: 1-[(9Z)-octadec-9-enoyl]-2-hexadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol)(1-) + O2 + a reduced electron acceptor = 1-18:2-2-16:0-phosphatidylglycerol + 2 H2O + an oxidized electron acceptor.


name: regulation of postsynaptic cytosolic calcium ion concentration

description: Any process that regulates the concentration of calcium in the postsynaptic cytosol.


description: Catalysis of the reaction: monomethylamine + a monomethylamine corrinoid protein = a methylated monomethylamine corrinoid protein + NH3.


negative regulation of fear response

description: Any process that stops, prevents or reduces the frequency, rate or extent of fear response.


name: formation of stylet for nutrient acquisition

description: The assembly of a stylet, a hollow protrusible spear-like symbiont structure projected into the host cell for the purpose of obtaining nutrients. The host is defined as the larger of the organisms involved in a symbiotic interaction.


mandelamide amidase activity

description: Catalysis of the reaction: (R)-mandelamide + H2O = (R)-mandelate + NH4.


shamixanthone metabolic process

description: The chemical reactions and pathways involving shamixanthone.


name: symbiont-mediated perturbation of host salicylic acid-mediated signal transduction pathway

description: A process in which a symbiont alters or subverts a salicylic acid-mediated signal transduction pathway in its host. The host is defined as the larger of the organisms involved in a symbiotic interaction.


name: positive regulation of nematode pharynx morphogenesis

description: Any process that activates or increases the frequency, rate or extent of nematode pharynx morphogenesis.


name: high-affinity copper ion transmembrane transporter activity

description: Enables the transfer of a copper ions (Cu2+) from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.


ventriculo bulbo valve formation

description: The developmental process pertaining to the initial formation of the ventriculo bulbo valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable.


description: Catalysis of the reaction: (R)-2-hydroxyglutaryl-CoA = H2O + glutaconyl-CoA.


name: dihydroorotate dehydrogenase (NAD+) activity

description: Catalysis of the reaction: (S)-dihydroorotate + NAD+ = H+ + NADH + orotate.


name: symbiont-mediated disruption of host cellular anatomical entity

description: The process in which an organism effects a change that impairs the structure or function of a host cellular anatomical entity. The host is defined as the larger of the organisms involved in a symbiotic interaction.


name: pyridoxal transmembrane transporter activity

description: Enables the transfer of pyridoxal from one side of a membrane to the other. Pyridoxal, 3-hydroxy-5-(hydroxymethyl)-2-methyl-4-pyridinecarboxaldehyde, is one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate.


4-alpha-glucanotransferase activity

description: Catalysis of the transfer of a segment of a (1->4)-alpha-D-glucan to a new 4-position in an acceptor, which may be glucose or (1->4)-alpha-D-glucan.


name: symbiont-mediated suppression of host JAK-STAT cascade via inhibition of STAT activity

description: A process in which a symbiont interferes with, inhibits or disrupt a JAK-STAT signal cascade in the host organism by reducing the activity of host STAT (signal transducer and activator of transcription). STATs are SH2 domain-containing proteins which lie downstream of many signaling receptors. Upon phosphorylation by JAKs, STAT proteins hetero- or homo-dimerize and translocate to the nucleus to activate transcription of target genes.


description: Catalysis of the reaction: indole-3-acetate + L-glutamate + ATP = H+ + indole-3-acetyl-glutamate + AMP + diphosphoric acid.


name: RNA NAD-cap (NMN-forming) hydrolase activity

description: Catalysis of the reaction: a 5'-end NAD+-phospho-ribonucleoside in mRNA + H2O = a 5'-end phospho-adenosine-phospho-ribonucleoside in mRNA + beta-nicotinamide D-ribonucleotide + 2 H+.


trichloroethylene metabolic process

description: The chemical reactions and pathways involving trichloroethylene, a toxic, colorless, photoreactive, chlorinated hydrocarbon liquid, commonly used as a metal degreaser and solvent.


name: regulation of epithelial to mesenchymal transition involved in endocardial cushion formation

description: Any process that modulates the frequency, rate or extent of epithelial to mesenchymal transition involved in endocardial cushion formation.


anal fin morphogenesis

description: The process in which the anatomical structures of the anal fin are generated and organized. An anal fin is an unpaired medial fin on the ventral aspect near the caudal end of a fish, which provides lateral stability while swimming.


name: negative regulation of cilium-dependent cell motility

description: Any process that stops, prevents or reduces the frequency, rate or extent of cilium-dependent cell motility.


interleukin-9 production

description: The appearance of interleukin-9 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


pseurotin A metabolic process

description: The chemical reactions and pathways involving pseurotin A.


name: baroreceptor detection of increased arterial stretch

description: The series of events by which an increase in diameter of an artery is detected and converted to a molecular signal.


pyridoxal 4-dehydrogenase activity

description: Catalysis of the reaction: NAD+ + pyridoxal = 4-pyridoxolactone + H+ + NADH.


response to ecdysone

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ecdysone stimulus.


immune response

description: Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat.


name: nuclear polyadenylation-dependent CUT catabolic process

description: The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of a cryptic unstable transcript (CUT), initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target CUT.


name: regulation of nerve growth factor receptor activity

description: Any process that modulates the frequency, rate or extent of the activity of the nerve growth factor (NGF) receptor.


description: Catalysis of the reaction: 4-acetamidobutanoate + H2O = acetate + 4-aminobutanoate.


name: neural crest cell differentiation involved in thymus development

description: Any neural crest cell differentiation that is involved in thymus development.


pyruvate decarboxylase activity

description: Catalysis of the reaction: a 2-oxo acid = an aldehyde + CO2.


name: modulation by symbiont of host heat acclimation

description: Any process in which an organism modulates the host's tolerance to high temperatures, above the optimal temperature for that organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.


name: specification of segmental identity, mandibular segment

description: The specification of the characteristic structures of the mandibular segment following establishment of segment boundaries. Identity is considered to be the aggregate of characteristics by which a structure is recognized.


name: CTP:geranylgeraniol kinase activity

description: Catalysis of the reaction: geranylgeraniol + CTP = all-trans-geranyl-geranyl monophosphate + CDP.


deoxyinosine salvage

description: Any process that generates deoxyinosine from derivatives of it, without de novo synthesis.


name: valine N-monooxygenase (oxime forming) activity

description: Catalysis of the reaction: L-valine + 2 O2 + 2 NADPH(4-) + 2 H+ = (E)-2-methylpropanal oxime + 2 NADP(3-) + carbon dioxide + 3 H2O.


name: symbiont-mediated suppression of host adaptive immune response

description: A process by which a symbiont inhibits or disrupts the normal execution of the adaptive immune response of the host organism, an immune response based on directed amplification of specific receptors for antigen produced through a somatic diversification process, and allowing for enhanced response to subsequent exposures to the same antigen (immunological memory).


valine biosynthetic process

description: The chemical reactions and pathways resulting in the formation of valine, 2-amino-3-methylbutanoic acid.


name: negative regulation of granuloma formation

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of granuloma formation.


name: positive regulation of synaptic plasticity by chemical substance

description: The process in which a chemical substance increases synaptic plasticity, the ability of synapses to change as circumstances require.


name: regulation of arugosin biosynthetic process

description: Any process that modulates the frequency, rate or extent of arugosin biosynthetic process.


imaginal disc pattern formation

description: The regionalization process that results in defined areas of the imaginal disc that will undergo specific cell differentaiton. Imaginal discs are epithelial infoldings in the larvae of holometabolous insects that develop into adult appendages (legs, antennae, wings, etc.) during metamorphosis from larval to adult form.


actin ubiquitination

description: The modification of actin by addition of ubiquitin groups.


name: 9,10 (9', 10')-carotenoid-cleaving dioxygenase activity

description: Catalysis of the oxidative cleavage of carotenoids at the (9, 10) and/or (9', 10') double bond.


pollen intine formation

description: Formation of pollen intine, the inner layer of the pollen wall. The reticulate pollen wall pattern consists of two layers, exine and intine.


name: negative regulation of proteinase activated receptor activity

description: Any process that stops, prevents or reduces the frequency, rate or extent of proteinase activated receptor activity.


description: Catalysis of the reaction: N(2)-(2-carboxyethyl)-L-arginine + ATP = AMP + deoxyamidinoproclavaminate + diphosphate + 2 H+.


name: myotube cell development involved in skeletal muscle regeneration

description: The process aimed at the progression of a myotube cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. This occurs as part of the process of skeletal muscle regeneration. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse.


granulosa cell proliferation

description: The multiplication or reproduction of granulosa cells, resulting in the expansion of the granulosa cells population. A granulosa cell is a supporting cell for the developing female gamete in the ovary of mammals. They develop from the coelomic epithelial cells of the gonadal ridge.


description: Catalysis of the reaction: CMP-N-acetyl-beta-neuraminate + 2 Fe(II)-[cytochrome b5] + 2 H+ + O2 = CMP-N-glycoloyl-beta-neuraminate + 2 Fe(III)-[cytochrome b5] + H2O.


name: negative regulation of paraxial mesodermal cell fate specification

description: Any process that stops, prevents, or reduces the frequency, rate or extent of paraxial mesoderm cell fate specification.


glucuronoarabinoxylan metabolic process

description: The chemical reactions and pathways involving xylan, a polymer containing a beta-(1->4)-linked D-xylose backbone decorated with glucuronic acid and arabinose side units.


name: calcium-induced calcium release activity involved in regulation of postsynaptic cytosolic calcium ion concentration

description: Any calcium-induced calcium release activity that is involved in regulation of postsynaptic cytosolic calcium ion concentration.


response to 5-fluorouracil

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 5-fluorouracil stimulus.


name: negative regulation of cardiac muscle cell contraction

description: Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle cell contraction.


appendage segmentation

description: Division of an appendage, an organ or part that is attached to the main body of an organism, into a series of semi-repetitive parts or segments. Most arthropod appendages, such as the legs and antennae, are visibly segmented.


name: peptide mating pheromone maturation involved in regulation of pheromone-induced unidirectional conjugation

description: The formation of a mature peptide mating pheromone by proteolysis and/or modification of a peptide precursor, occurring in the context of pheromone-induced unidirectional conjugation.


protein decanoylation

description: The modification of a protein amino acid by formation of an ester or amide with decanoic acid.


name: negative regulation of cellular response to X-ray

description: Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to X-ray.


octanol metabolic process

description: The chemical reactions and pathways involving octanol, the 8-carbon alcohol with the formula C8H17OH.


mannogen metabolic process

description: The chemical reactions and pathways involving mannogen, a mannose-containing polysaccharide that is a major energy reserve in Leishmania.


glucosinolate biosynthetic process

description: The chemical reactions and pathways resulting in the formation of glucosinolates, substituted thioglucosides found in rapeseed products and related cruciferae.


bidentate ribonuclease III activity

description: Catalysis of the digestion of double-stranded RNAs into 20 to 30-nucleotide products. These products typically associate to the RNA-induced silencing complex and serve as guide RNAs for posttranslational RNA interference.


lipid III floppase activity

description: Enables the transbilayer of capsular-polysaccharides (Und-PP-GlcNAc-ManNAcA-Fuc4NAc (lipid III)) from the inner to the outer leaflet of the cytoplasmic membrane during the assembly of ECA. Capsular polysaccharides make up the capsule, a protective structure surrounding some species of bacteria and fungi.


D-xylulose reductase activity

description: Catalysis of the reaction: NAD+ + xylitol = D-xylulose + H+ + NADH.


orthodenticle mRNA localization

description: Any process in which orthodenticle mRNA is transported to and maintained in the oocyte and/or syncytial embryo as part of the process that will specify the anterior/posterior axis.


name: tricyclic triterpenoid metabolic process

description: The chemical reactions and pathways involving tricyclic triterpenoid compounds, terpenoids with six isoprene units and 3 rings.


description: Catalysis of the reaction: N(2)-benzoyl-D-arginine-4-nitroanilide + H2O = 4-nitroaniline + N(2)-benzoyl-D-arginine + H+.


citrate-CoA ligase activity

description: Catalysis of the reaction: ATP + citrate + CoA = (3S)-citryl-CoA + ADP + H+ + phosphate.


name: epithelial cell type specification, open tracheal system

description: Allocation of epithelial cells within each migrating branch in an open tracheal system to distinct tracheal cell fates. During the migration phase each branch forms a well-defined number of cell types (including fusion cells, terminal cells and branch cells) at precise positions.


mesonephric podocyte development

description: The process whose specific outcome is the progression of a mesonephric glomerular visceral epithelial cell over time, from its formation to the mature structure. A mesonephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the mesonephros.


mucilage extrusion from seed coat

description: The process in which seed mucilage expands through hydration and breaks the outer cell wall that encapsulates the whole seed upon imbibition. Mucilage, mainly composed of pectins, is formed during seed development and deposited into the apoplast underneath the outer wall of the seed coat.


arsenite methyltransferase activity

description: Catalysis of the reaction: S-adenosyl-L-methionine + arsenite = S-adenosyl-L-homocysteine + methylarsonate.


name: negative regulation of ARF protein signal transduction

description: Any process that stops, prevents, or reduces the frequency, rate or extent of ARF protein signal transduction.


N-cyclopropylmelamine metabolic process

description: The chemical reactions and pathways involving N-cyclopropylmelamine, a triazine compound commonly used as an insect growth regulator insecticide.


tricellular tight junction assembly

description: The aggregation, arrangement and bonding together of a set of components to form a tricellular tight junction.


description: Catalysis of the reaction: ATP(4-) + H2O + a cis-keto-C60-meroacyl-[acp] = diphosphoric acid + a cis-keto-meroacyl-adenylate + a holo-[acyl-carrier protein].


name: cell-cell adhesion involved in cerebral cortex tangential migration using cell-cell interactions

description: The attachment of cells to one another to form groups of cells involved in cerebral cortex tangential migration.


name: negative regulation of growth factor dependent skeletal muscle satellite cell proliferation

description: Any process that stops, prevents or reduces the frequency, rate or extent of satellite cell proliferation; dependent on specific growth factor activity such as fibroblast growth factors and transforming growth factor beta.


diphthine-ammonia ligase activity

description: Catalysis of the reaction: ATP + diphthine + NH4 = ADP + diphthamide + H+ + phosphate.


name: positive regulation of amoeboid sperm motility

description: Any process that activates or increases the frequency, rate or extent of amoeboid sperm motility.


description: Catalysis of the reaction: L-ribulose 5-phosphate = L-xylulose 5-phosphate.


mesonephric glomerulus development

description: The progression of the mesonephric glomerulus over time from its initial formation until its mature state. The mesonephric glomerulus is a capillary tuft which forms a close network with the visceral epithelium (podocytes) and the mesangium to form the filtration barrier and is surrounded by Bowman's capsule in nephrons of the mature vertebrate kidney, or mesonephros.


carboxymethylhydantoinase activity

description: Catalysis of the reaction: L-5-carboxymethylhydantoin + H2O = N-carbamoyl-L-aspartate + H+.


name: negative regulation of cell communication

description: Any process that decreases the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.


eye blink reflex

description: The reflex process in which a mechanical stimulus applied to the eye elicits a response of the eyelid closing.


description: Catalysis of the reaction: 5'-acylphosphoadenosine + H2O = AMP + a carboxylate.


defasciculation of motor neuron axon

description: Separation of a motor axon away from a bundle of axons known as a fascicle.


description: Catalysis of the reaction: 3-hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA + 4 H+ = 7-methyl-3-oxooct-6-enoyl-CoA + acetate.


name: 4-cresol dehydrogenase (hydroxylating) activity

description: Catalysis of the reaction: 4-cresol + acceptor + H2O = 4-hydroxybenzaldehyde + reduced acceptor.


name: pigment accumulation in tissues in response to UV light

description: The aggregation of coloring matter in a particular location in a tissue, occurring in response to a UV light stimulus.


name: activated CD4-positive, alpha-beta T cell apoptotic process

description: Any apoptotic process in an activated CD4-positive, alpha-beta T cell.