name: 3BP5L_HUMAN SH3 domain-binding protein 5-like (sprot)

description: An SH3 domain-binding protein 5-like that is encoded in the genome of human.


name: FAKD5_HUMAN FAST kinase domain-containing protein 5, mitochondrial (sprot)

description: A FAST kinase domain-containing protein 5, mitochondrial that is encoded in the genome of human.


mitochondrial RNA processing

category: biolink:BiologicalProcess biolink:Occurrent biolink:OntologyClass biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: The conversion of a primary RNA molecule transcribed from a mitochondrial genome into one or more mature RNA molecules; occurs in the mitochondrion.


name: OTU6A_HUMAN OTU domain-containing protein 6A (sprot)

description: An OTU domain-containing protein 6A that is encoded in the genome of human.


name: DPH6_HUMAN Diphthine--ammonia ligase (sprot)

description: A diphthine--ammonia ligase that is encoded in the genome of human.


diphthine-ammonia ligase activity

category: biolink:MolecularActivity biolink:Occurrent biolink:OntologyClass biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: Catalysis of the reaction: ATP + diphthine + NH4 = ADP + diphthamide + H+ + phosphate.


name: ZN627_HUMAN Zinc finger protein 627 (sprot)

description: A zinc finger protein 627 that is encoded in the genome of human.


name: LIGO2_HUMAN Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 2 (sprot)

description: A leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 2 that is encoded in the genome of human.


name: EEPD1_HUMAN Endonuclease/exonuclease/phosphatase family domain-containing protein 1 (sprot)

description: An endonuclease/exonuclease/phosphatase family domain-containing protein 1 that is encoded in the genome of human.


name: MOB1B_HUMAN MOB kinase activator 1B (sprot)

description: A MOB kinase activator 1B that is encoded in the genome of human.


name: KDM3B_HUMAN Lysine-specific demethylase 3B (sprot)

description: A lysine-specific demethylase 3B that is encoded in the genome of human.


name: S26A9_HUMAN Solute carrier family 26 member 9 (sprot)

description: A solute carrier family 26 member 9 that is encoded in the genome of human.


name: CHM1B_HUMAN Charged multivesicular body protein 1b (sprot)

description: A charged multivesicular body protein 1b that is encoded in the genome of human.


name: ARC_HUMAN Activity-regulated cytoskeleton-associated protein (sprot)

description: An activity-regulated cytoskeleton-associated protein that is encoded in the genome of human.


virus-like capsid

category: biolink:CellularComponent biolink:AnatomicalEntity biolink:PhysicalEssence biolink:OrganismalEntity biolink:SubjectOfInvestigation biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: A protein coat that surrounds nucleic acid to form a structure similar to a virus capsid. Virus-like capsids are non-infectious and are encoded by endogenous (non-viral) genes. Fly and tetrapod Arc (ancestrally-related to retrotransposon Gag) are examples of proteins that can self-assemble into capsid-like structures which encapsulate Arc mRNA and mediate the intercellular transmission of RNA.


name: GRP2_HUMAN RAS guanyl-releasing protein 2 (sprot)

description: A RAS guanyl-releasing protein 2 that is encoded in the genome of human.


name: GAK6_HUMAN Endogenous retrovirus group K member 6 Gag polyprotein (sprot)


name: CXXC5_HUMAN CXXC-type zinc finger protein 5 (sprot)

description: A CXXC-type zinc finger protein 5 that is encoded in the genome of human.


name: CHSTF_HUMAN Carbohydrate sulfotransferase 15 (sprot)

description: A carbohydrate sulfotransferase 15 that is encoded in the genome of human.


name: N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity

description: Catalysis of the reactions: 3'-phosphoadenylyl sulfate + dermatan = adenosine 3',5'-bisphosphate + dermatan 6'-sulfate and 3'-phosphoadenylyl sulfate + chondroitin = adenosine 3',5'-bisphosphate + chondroitin 6'-sulfate.


hexose biosynthetic process

description: The chemical reactions and pathways resulting in the formation of hexose, any monosaccharide with a chain of six carbon atoms in the molecule.


name: RIR2B_HUMAN Ribonucleoside-diphosphate reductase subunit M2 B (sprot)

description: A ribonucleoside-diphosphate reductase subunit M2 B that is encoded in the genome of human.


name: deoxyribonucleoside triphosphate metabolic process

description: The chemical reactions and pathways involving a deoxyribonucleoside triphosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with triphosphate on the sugar.


name: HS2ST_HUMAN Heparan sulfate 2-O-sulfotransferase 1 (sprot)

description: A heparan sulfate 2-O-sulfotransferase 1 that is encoded in the genome of human.


name: heparan sulfate 2-O-sulfotransferase activity

description: Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + heparan sulfate = adenosine 3',5'-bisphosphate + heparan sulfate 2-O-sulfate; results in 2-O-sulfation of iduronic acid residues in heparan sulfate.


name: CHST3_HUMAN Carbohydrate sulfotransferase 3 (sprot)

description: A carbohydrate sulfotransferase 3 that is encoded in the genome of human.


chondroitin 6-sulfotransferase activity

description: Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + chondroitin = adenosine 3',5'-bisphosphate + chondroitin 6'-sulfate.


proteoglycan sulfotransferase activity

description: Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + proteoglycan = adenosine 3',5'-bisphosphate + proteoglycan sulfate. A proteoglycan is a glycoprotein whose carbohydrate units are glycosaminoglycans.


name: SHF_HUMAN SH2 domain-containing adapter protein F (sprot)

description: An SH2 domain-containing adapter protein F that is encoded in the genome of human.


name: OTOP1_HUMAN Proton channel OTOP1 (sprot)

description: A proton channel OTOP1 that is encoded in the genome of human.


proton channel activity

description: Enables the facilitated diffusion of a hydrogen ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.


detection of gravity

description: The series of events in which a gravitational stimulus is received and converted into a molecular signal.


name: STRAA_HUMAN STE20-related kinase adapter protein alpha (sprot)

description: A STE20-related kinase adapter protein alpha that is encoded in the genome of human.


name: NIPA1_HUMAN Magnesium transporter NIPA1 (sprot)

description: A magnesium transporter NIPA1 that is encoded in the genome of human.


name: MICA3_HUMAN [F-actin]-monooxygenase MICAL3 (sprot)

description: An [F-actin]-monooxygenase MICAL3 that is encoded in the genome of human.


name: NLRP9_HUMAN NACHT, LRR and PYD domains-containing protein 9 (sprot)

description: A NACHT, LRR and PYD domains-containing protein 9 that is encoded in the genome of human.


name: NLRC3_HUMAN NLR family CARD domain-containing protein 3 (sprot)

description: An NLR family CARD domain-containing protein 3 that is encoded in the genome of human.


name: T2R42_HUMAN Taste receptor type 2 member 42 (sprot)

description: A taste receptor type 2 member 42 that is encoded in the genome of human.


name: BHA15_HUMAN Class A basic helix-loop-helix protein 15 (sprot)

description: A class A basic helix-loop-helix protein 15 that is encoded in the genome of human.


name: PTF1A_HUMAN Pancreas transcription factor 1 subunit alpha (sprot)

description: A pancreas transcription factor 1 subunit alpha that is encoded in the genome of human.


name: OTOP3_HUMAN Proton channel OTOP3 (sprot)

description: A proton channel OTOP3 that is encoded in the genome of human.


name: OTOP2_HUMAN Proton channel OTOP2 (sprot)

description: A proton channel OTOP2 that is encoded in the genome of human.


name: K2C74_HUMAN Keratin, type II cytoskeletal 74 (sprot)

description: A keratin, type II cytoskeletal 74 that is encoded in the genome of human.


DYM_HUMAN Dymeclin (sprot)

A dymeclin that is encoded in the genome of human.


name: SSX9_HUMAN Putative protein SSX9 (sprot)

description: A putative protein SSX9 that is encoded in the genome of human.


name: SSX8_HUMAN Putative protein SSX8 (sprot)

description: A putative protein SSX8 that is encoded in the genome of human.


SSX7_HUMAN Protein SSX7 (sprot)

A protein SSX7 that is encoded in the genome of human.


name: SSX6_HUMAN Putative protein SSX6 (sprot)

description: A putative protein SSX6 that is encoded in the genome of human.


name: S29A4_HUMAN Equilibrative nucleoside transporter 4 (sprot)

description: An equilibrative nucleoside transporter 4 that is encoded in the genome of human.


name: organic acid transmembrane transporter activity

description: Enables the transfer of organic acids from one side of a membrane to the other. Organic acids are acidic compound containing carbon in covalent linkage.


organic acid transmembrane transport

description: The process in which an organic acid is transported across a membrane.


name: TCF24_HUMAN Transcription factor 24 (sprot)

description: A transcription factor 24 that is encoded in the genome of human.


name: TCF23_HUMAN Transcription factor 23 (sprot)

description: A transcription factor 23 that is encoded in the genome of human.


name: OLIG3_HUMAN Oligodendrocyte transcription factor 3 (sprot)

description: An oligodendrocyte transcription factor 3 that is encoded in the genome of human.


spinal cord motor neuron migration

description: The orderly movement of a spinal cord motor neuron from one site to another. A spinal cord motor neuron is a motor neuron that passes from the spinal cord toward or to a muscle and conducts an impulse that causes movement.


name: BHA09_HUMAN Class A basic helix-loop-helix protein 9 (sprot)

description: A class A basic helix-loop-helix protein 9 that is encoded in the genome of human.


name: ASCL5_HUMAN Achaete-scute homolog 5 (sprot)

description: An achaete-scute homolog 5 that is encoded in the genome of human.


name: SCX_HUMAN Basic helix-loop-helix transcription factor scleraxis (sprot)

description: A basic helix-loop-helix transcription factor scleraxis that is encoded in the genome of human.


tendon formation

description: The process that gives rise to a tendon. This process pertains to the initial formation of a tendon from unspecified parts.


STRC_HUMAN Stereocilin (sprot)

A stereocilin that is encoded in the genome of human.


name: PHF5A_HUMAN PHD finger-like domain-containing protein 5A (sprot)

description: A PHD finger-like domain-containing protein 5A that is encoded in the genome of human.


name: GSTA5_HUMAN Glutathione S-transferase A5 (sprot)

description: A glutathione S-transferase A5 that is encoded in the genome of human.


name: ZN367_HUMAN Zinc finger protein 367 (sprot)

description: A zinc finger protein 367 that is encoded in the genome of human.


name: PXL2C_HUMAN Peroxiredoxin-like 2C (sprot)

description: A peroxiredoxin-like 2C that is encoded in the genome of human.


OTOAN_HUMAN Otoancorin (sprot)

An otoancorin that is encoded in the genome of human.


name: TS1R3_HUMAN Taste receptor type 1 member 3 (sprot)

description: A taste receptor type 1 member 3 that is encoded in the genome of human.


sweet taste receptor activity

description: Combining with soluble sweet compounds to initiate a change in cell activity. These receptors are responsible for the sense of sweet taste.


name: detection of chemical stimulus involved in sensory perception of sweet taste

description: The series of events required for a sweet taste stimulus to be received and converted to a molecular signal.


sweet taste receptor complex

description: A protein complex which is capable of sweet taste receptor activity.


name: TS1R1_HUMAN Taste receptor type 1 member 1 (sprot)

description: A taste receptor type 1 member 1 that is encoded in the genome of human.


name: CTSR4_HUMAN Cation channel sperm-associated protein 4 (sprot)

description: A cation channel sperm-associated protein 4 that is encoded in the genome of human.


name: MOT14_HUMAN Monocarboxylate transporter 14 (sprot)

description: A monocarboxylate transporter 14 that is encoded in the genome of human.


name: MOT13_HUMAN Monocarboxylate transporter 13 (sprot)

description: A monocarboxylate transporter 13 that is encoded in the genome of human.


name: MOT9_HUMAN Monocarboxylate transporter 9 (sprot)

description: A monocarboxylate transporter 9 that is encoded in the genome of human.


OVCH1_HUMAN Ovochymase-1 (sprot)

An ovochymase-1 that is encoded in the genome of human.


name: TMPS7_HUMAN Transmembrane protease serine 7 (sprot)

description: A transmembrane protease serine 7 that is encoded in the genome of human.


PRS41_HUMAN Serine protease 41 (sprot)

A testis serine protease 1 that is encoded in the genome of human.


OVCH2_HUMAN Ovochymase-2 (sprot)

An ovochymase-2 that is encoded in the genome of human.


name: U17L1_HUMAN Ubiquitin carboxyl-terminal hydrolase 17-like protein 1 (sprot)

description: A protein that is a translation product of the USP17L1 gene in human.


name: PLPR4_HUMAN Phospholipid phosphatase-related protein type 4 (sprot)

description: A phospholipid phosphatase-related protein type 4 that is encoded in the genome of human.


APTX_HUMAN Aprataxin (sprot)

An aprataxin that is encoded in the genome of human.


name: DNA 5'-adenosine monophosphate hydrolase activity

description: Catalysis of the reaction: 5'-AMP-DNA + H2O = AMP + DNA; nucleophilic release of a covalently linked adenylate residue from a DNA strand, leaving a 5' phosphate terminus.


description: Catalysis of the reaction: (DNA)-3'-diphospho-5'-guanosine + H2O = (DNA)-3'-phosphate + GMP.


name: KRBX5_HUMAN KRAB domain-containing protein 5 (sprot)

description: A KRAB domain-containing protein 5 that is encoded in the genome of human.


name: H2BWT_HUMAN Histone H2B type W-T (sprot)

description: A histone H2B type W-T that is encoded in the genome of human.


name: S36A1_HUMAN Proton-coupled amino acid transporter 1 (sprot)

description: A proton-coupled amino acid transporter 1 that is encoded in the genome of human.


name: ERMP1_HUMAN Endoplasmic reticulum metallopeptidase 1 (sprot)

description: An endoplasmic reticulum metallopeptidase 1 that is encoded in the genome of human.


name: GRIN1_HUMAN G protein-regulated inducer of neurite outgrowth 1 (sprot)

description: A G protein-regulated inducer of neurite outgrowth 1 that is encoded in the genome of human.


name: LRR70_HUMAN Leucine-rich repeat-containing protein 70 (sprot)

description: A leucine-rich repeat-containing protein 70 that is encoded in the genome of human.


name: SSAS1_HUMAN Putative uncharacterized protein SSBP3-AS1 (sprot)


TRM1L_HUMAN TRMT1-like protein (sprot)

A TRM1-like protein that is encoded in the genome of human.


description: Catalysis of the reaction: guanosine(10) in tRNA + S-adenosyl-L-methionine = H+ + N(2)-methylguanosine(10) in tRNA + S-adenosyl-L-homocysteine.


name: ZCCHV_HUMAN Zinc finger CCCH-type antiviral protein 1 (sprot)

description: A zinc finger CCCH-type antiviral protein 1 that is encoded in the genome of human.


name: TRPM8_HUMAN Transient receptor potential cation channel subfamily M member 8 (sprot)

description: A transient receptor potential cation channel TRPM8 that is encoded in the genome of human.


name: RM21_HUMAN Large ribosomal subunit protein bL21m (sprot)

description: A large ribosomal subunit protein bL21m that is encoded in the genome of human.


name: PCLI1_HUMAN PTB-containing, cubilin and LRP1-interacting protein (sprot)

description: A PTB-containing, cubilin and LRP1-interacting protein that is encoded in the genome of human.


regulation of mitochondrial fusion

description: Any process that modulates the frequency, rate or extent of merging of two or more mitochondria within a cell to form a single compartment.


name: PAGE2_HUMAN P antigen family member 2 (sprot)

description: A G antigen family E member 2 that is encoded in the genome of human.


name: NRK_HUMAN Nik-related protein kinase (sprot)

description: A Nik-related protein kinase that is encoded in the genome of human.


name: GVIN1_HUMAN Interferon-induced very large GTPase 1 (sprot)

description: An interferon-induced very large GTPase 1 that is encoded in the genome of human.


TICRR_HUMAN Treslin (sprot)

A treslin that is encoded in the genome of human.


name: EFL1_HUMAN Elongation factor-like GTPase 1 (sprot)

description: An elongation factor-like GTPase 1 that is encoded in the genome of human.


name: MAMC2_HUMAN MAM domain-containing protein 2 (sprot)

description: A MAM domain-containing protein 2 that is encoded in the genome of human.


name: PBIR2_HUMAN PABIR family member 2 (sprot)

description: A PABIR family member 2 that is encoded in the genome of human.


name: SETX_HUMAN Probable helicase senataxin (sprot)

description: A probable helicase senataxin that is encoded in the genome of human.


name: transcription termination site sequence-specific DNA binding

description: Binding to a sequence of DNA that promotes termination by RNA polymerase. The transcribed region might be described as a gene, cistron, or operon.


name: positive regulation of termination of DNA-templated transcription

description: Any process that increases the rate, frequency or extent of DNA-templated transcription termination, the process in which transcription is completed; the formation of phosphodiester bonds ceases, the RNA-DNA hybrid dissociates, and RNA polymerase releases the DNA.


name: positive regulation of termination of RNA polymerase II transcription, poly(A)-coupled

description: Any process that activates or increases the frequency, rate or extent of termination of RNA polymerase II transcription, poly(A)-coupled.


name: ZN551_HUMAN Zinc finger protein 551 (sprot)

description: A zinc finger protein 551 that is encoded in the genome of human.


name: HDX_HUMAN Highly divergent homeobox (sprot)

description: A highly divergent homeobox that is encoded in the genome of human.


name: TPC11_HUMAN Trafficking protein particle complex subunit 11 (sprot)

description: A trafficking protein particle complex subunit 11 that is encoded in the genome of human.


name: ZN550_HUMAN Zinc finger protein 550 (sprot)

description: A zinc finger protein 550 that is encoded in the genome of human.


name: SIM15_HUMAN Small integral membrane protein 15 (sprot)

description: A small integral membrane protein 15 that is encoded in the genome of human.


name: NEGR1_HUMAN Neuronal growth regulator 1 (sprot)

description: A neuronal growth regulator 1 that is encoded in the genome of human.


name: KANL1_HUMAN KAT8 regulatory NSL complex subunit 1 (sprot)

description: A KAT8 regulatory NSL complex subunit 1 that is encoded in the genome of human.


name: regulation of mitochondrial transcription

description: Any process that modulates the frequency, rate or extent of transcription occurring in the mitochondrion.


NUP54_HUMAN Nucleoporin p54 (sprot)

A nucleoporin p54 that is encoded in the genome of human.


name: ATG9A_HUMAN Autophagy-related protein 9A (sprot)

description: An autophagy-related protein 9A that is encoded in the genome of human.


name: LYSM3_HUMAN LysM and putative peptidoglycan-binding domain-containing protein 3 (sprot)

description: A LysM and putative peptidoglycan-binding domain-containing protein 3 that is encoded in the genome of human.


name: GLUCM_HUMAN D-glutamate cyclase, mitochondrial (sprot)

description: A D-glutamate cyclase, mitochondrial that is encoded in the genome of human.


D-glutamate cyclase activity

description: Catalysis of the reaction: D-glutamate = 5-oxo-D-proline + H2O.


name: PARPT_HUMAN Protein mono-ADP-ribosyltransferase TIPARP (sprot)

description: A protein mono-ADP-ribosyltransferase TIPARP that is encoded in the genome of human.


name: CC186_HUMAN Coiled-coil domain-containing protein 186 (sprot)

description: A coiled-coil domain-containing protein 186 that is encoded in the genome of human.


name: ARMC9_HUMAN LisH domain-containing protein ARMC9 (sprot)

description: A LisH domain-containing protein ARMC9 that is encoded in the genome of human.


name: LYCHS_HUMAN Lysosomal cholesterol signaling protein (sprot)

description: A lysosomal cholesterol signaling protein that is encoded in the genome of human.


name: PRIC2_HUMAN Prickle-like protein 2 (sprot)

description: A prickle-like protein 2 that is encoded in the genome of human.


name: PANKY_HUMAN Photoreceptor ankyrin repeat protein (sprot)

description: A photoreceptor ankyrin repeat protein that is encoded in the genome of human.


name: SAMD7_HUMAN Sterile alpha motif domain-containing protein 7 (sprot)

description: A sterile alpha motif domain-containing protein 7 that is encoded in the genome of human.


name: ZN572_HUMAN Zinc finger protein 572 (sprot)

description: A zinc finger protein 572 that is encoded in the genome of human.


name: VP35L_HUMAN VPS35 endosomal protein-sorting factor-like (sprot)

description: A VPS35 endosomal protein-sorting factor-like that is encoded in the genome of human.


name: POGZ_HUMAN Pogo transposable element with ZNF domain (sprot)

description: A pogo transposable element with ZNF domain that is encoded in the genome of human.


name: MIER3_HUMAN Mesoderm induction early response protein 3 (sprot)

description: A mesoderm induction early response protein 3 that is encoded in the genome of human.


name: S46A3_HUMAN Lysosomal proton-coupled steroid conjugate and bile acid symporter SLC46A3 (sprot)

description: A lysosomal proton-coupled steroid conjugate and bile acid symporter SLC46A3 that is encoded in the genome of human.


vacuolar transmembrane transport

description: The process in which a solute is transported from one side of the vacuolar membrane to the other.


name: CA2D4_HUMAN Voltage-dependent calcium channel subunit alpha-2/delta-4 (sprot)

description: A voltage-dependent calcium channel subunit alpha-2/delta-4 that is encoded in the genome of human.


name: NT2NA_HUMAN Notch homolog 2 N-terminal-like protein A (sprot)

description: A notch homolog 2 N-terminal-like protein A that is encoded in the genome of human.


name: OR2W3_HUMAN Olfactory receptor 2W3 (sprot)

description: An olfactory receptor 2W3 that is encoded in the genome of human.


name: ZFY16_HUMAN Zinc finger FYVE domain-containing protein 16 (sprot)

description: A zinc finger FYVE domain-containing protein 16 that is encoded in the genome of human.


MON2_HUMAN Protein MON2 homolog (sprot)

A protein MON2 that is encoded in the genome of human.


name: ZN571_HUMAN Zinc finger protein 571 (sprot)

description: A zinc finger protein 571 that is encoded in the genome of human.


name: K1C28_HUMAN Keratin, type I cytoskeletal 28 (sprot)

description: A keratin, type I cytoskeletal 28 that is encoded in the genome of human.


name: K1C27_HUMAN Keratin, type I cytoskeletal 27 (sprot)

description: A keratin, type I cytoskeletal 27 that is encoded in the genome of human.


name: K1C26_HUMAN Keratin, type I cytoskeletal 26 (sprot)

description: A keratin, type I cytoskeletal 26 that is encoded in the genome of human.


name: K1C25_HUMAN Keratin, type I cytoskeletal 25 (sprot)

description: A keratin, type I cytoskeletal 25 that is encoded in the genome of human.


RD3_HUMAN Protein RD3 (sprot)

A protein RD3 that is encoded in the genome of human.


name: negative regulation of guanylate cyclase activity

description: Any process that stops, prevents, or reduces the frequency, rate or extent of guanylate cyclase activity.


PIWL3_HUMAN Piwi-like protein 3 (sprot)

A piwi-like protein 3 that is encoded in the genome of human.


PIWL4_HUMAN Piwi-like protein 4 (sprot)

A piwi-like protein 4 that is encoded in the genome of human.


piRNA binding

description: Binding to a piRNA, a Piwi-associated RNA, a 24- to 30-nucleotide RNA derived from repeat or complex DNA sequence elements and processed by a Dicer-independent mechanism.


secondary piRNA processing

description: A process leading to the generation of a functional secondary piRNA, involving a self-perpetuating piRNA loop, often called the ping-pong cycle, in which piRNAs are amplified by pairing with complementary transcripts (for example the transposable element mRNA target). In Drosophila, the processing involves the piwi proteins aubergine and Argonaute 3 and in mice, the piwi proteins Piwil2 and Piwil4.


piP-body

description: A P granule that contains the PIWIL4-TDRD9 module, a set of proteins that act in the secondary piRNA pathway.


name: MYCPP_HUMAN C-myc promoter-binding protein (sprot)

description: A C-myc promoter-binding protein that is encoded in the genome of human.


name: TMC7_HUMAN Transmembrane channel-like protein 7 (sprot)

description: A transmembrane channel-like protein 7 that is encoded in the genome of human.


name: TMC6_HUMAN Transmembrane channel-like protein 6 (sprot)

description: A transmembrane channel-like protein 6 that is encoded in the genome of human.


name: TMC4_HUMAN Transmembrane channel-like protein 4 (sprot)

description: A transmembrane channel-like protein 4 that is encoded in the genome of human.


MYH14_HUMAN Myosin-14 (sprot)

A myosin-14 that is encoded in the genome of human.


name: CSMD3_HUMAN CUB and sushi domain-containing protein 3 (sprot)

description: A CUB and sushi domain-containing protein 3 that is encoded in the genome of human.


name: CSMD2_HUMAN CUB and sushi domain-containing protein 2 (sprot)

description: A CUB and sushi domain-containing protein 2 that is encoded in the genome of human.


name: TMPS9_HUMAN Transmembrane protease serine 9 (sprot)

description: A transmembrane protease serine 9 that is encoded in the genome of human.


name: PEX26_HUMAN Peroxisome assembly protein 26 (sprot)

description: A peroxisome assembly protein 26 that is encoded in the genome of human.


name: NUFP2_HUMAN FMR1-interacting protein NUFIP2 (sprot)

description: An FMR1-interacting protein NUFIP2 that is encoded in the genome of human.


name: KCNKI_HUMAN Potassium channel subfamily K member 18 (sprot)

description: A potassium channel subfamily K member 18 that is encoded in the genome of human.


name: R144B_HUMAN E3 ubiquitin-protein ligase RNF144B (sprot)

description: An E3 ubiquitin-protein ligase RNF144B that is encoded in the genome of human.


LFG1_HUMAN Protein lifeguard 1 (sprot)

A glutamate [NMDA] receptor-associated protein 1 that is encoded in the genome of human.


name: MAVS_HUMAN Mitochondrial antiviral-signaling protein (sprot)

description: A mitochondrial antiviral-signaling protein that is encoded in the genome of human.


positive regulation of IP-10 production

description: Any process that activates or increases the frequency, rate, or extent of production of IP-10.


name: PK1L2_HUMAN Polycystin-1-like protein 2 (sprot)

description: A polycystin-1-like protein 2 that is encoded in the genome of human.


name: PK1L3_HUMAN Polycystin-1-like protein 3 (sprot)

description: A polycystin-1-like protein 3 that is encoded in the genome of human.


sour taste receptor activity

description: Combining with soluble sour compounds to initiate a change in cell activity. These receptors are responsible for the sense of sour taste.


name: detection of chemical stimulus involved in sensory perception of sour taste

description: The series of events required for a sour taste stimulus to be received and converted to a molecular signal.


RASE_HUMAN GTPase ERas (sprot)

A GTPase ERas that is encoded in the genome of human.


CP2U1_HUMAN Cytochrome P450 2U1 (sprot)

A cytochrome P450 2U1 that is encoded in the genome of human.


cytochrome metabolic process

description: The chemical reactions and pathways involving a cytochrome.


name: CLAP1_HUMAN CLIP-associating protein 1 (sprot)

description: A CLIP-associating protein 1 that is encoded in the genome of human.


centrosomal corona

description: An amorphous structure surrounding the core of the centrosome, from which microtubules are nucleated; contains gamma-tubulin.


name: BNIPL_HUMAN Bcl-2/adenovirus E1B 19 kDa-interacting protein 2-like protein (sprot)

description: A Bcl-2/adenovirus E1B 19 kDa-interacting protein 2-like protein that is encoded in the genome of human.


name: DHX29_HUMAN ATP-dependent RNA helicase DHX29 (sprot)

description: An ATP-dependent RNA helicase DHX29 that is encoded in the genome of human.


NPHP3_HUMAN Nephrocystin-3 (sprot)

A nephrocystin-3 that is encoded in the genome of human.


name: convergent extension involved in gastrulation

description: The morphogenetic process in which an epithelium narrows along one axis and lengthens in a perpendicular axis usually resulting in the formation of the three primary germ layers, ectoderm, mesoderm and endoderm.


name: determination of intestine left/right asymmetry

description: Determination of the asymmetric location of the intestine loops with respect to the left and right halves of the organism.


name: determination of stomach left/right asymmetry

description: Determination of the asymmetric location of the stomach with respect to the left and right halves of the organism.


name: regulation of Wnt signaling pathway, planar cell polarity pathway

description: Any process that modulates the frequency, rate or extent of Wnt signaling pathway, planar cell polarity pathway.


name: CR020_HUMAN Putative uncharacterized protein encoded by LINC00305 (sprot)


name: LRP10_HUMAN Low-density lipoprotein receptor-related protein 10 (sprot)

description: A low-density lipoprotein receptor-related protein 10 that is encoded in the genome of human.


name: COMD6_HUMAN COMM domain-containing protein 6 (sprot)

description: A COMM domain-containing protein 6 that is encoded in the genome of human.


name: TRM11_HUMAN tRNA (guanine(10)-N2)-methyltransferase homolog (sprot)

description: A tRNA guanosine-2'-O-methyltransferase TRM11 that is encoded in the genome of human.


name: HDDC2_HUMAN 5'-deoxynucleotidase HDDC2 (sprot)

description: A 5'-deoxynucleotidase HDDC2 that is encoded in the genome of human.


ADM2_HUMAN Protein ADM2 (sprot)

A protein ADM2 that is encoded in the genome of human.


name: HAUS6_HUMAN HAUS augmin-like complex subunit 6 (sprot)

description: A HAUS augmin-like complex subunit 6 that is encoded in the genome of human.


name: PLGT3_HUMAN Protein O-glucosyltransferase 3 (sprot)

description: A protein O-glucosyltransferase 3 that is encoded in the genome of human.


F220A_HUMAN Protein FAM220A (sprot)

A protein FAM220A that is encoded in the genome of human.


name: LIMS2_HUMAN LIM and senescent cell antigen-like-containing domain protein 2 (sprot)

description: A LIM and senescent cell antigen-like-containing domain protein 2 that is encoded in the genome of human.


name: negative regulation of cholangiocyte proliferation

description: Any process that stops, prevents or reduces the frequency, rate or extent of cholangiocyte proliferation.


name: GL6D1_HUMAN Putative glycosyltransferase 6 domain-containing protein 1 (sprot)

description: A putative glycosyltransferase 6 domain-containing protein 1 that is encoded in the genome of human.


name: TRI46_HUMAN Tripartite motif-containing protein 46 (sprot)

description: A tripartite motif-containing protein 46 that is encoded in the genome of human.


name: COX8C_HUMAN Cytochrome c oxidase subunit 8C, mitochondrial (sprot)

description: A cytochrome c oxidase subunit 8C, mitochondrial that is encoded in the genome of human.


name: TT21B_HUMAN Tetratricopeptide repeat protein 21B (sprot)

description: A tetratricopeptide repeat protein 21B that is encoded in the genome of human.


intraciliary retrograde transport

description: The directed movement of large protein complexes along microtubules from the tip of a cilium (also called flagellum) toward the cell body, mediated by motor proteins.


name: regulation of intraciliary retrograde transport

description: Any process that modulates the frequency, rate or extent of intraciliary retrograde transport.


intraciliary transport particle A

description: The smaller subcomplex of the intraciliary transport particle; characterized complexes have molecular weights of 710-760 kDa.


name: PPR42_HUMAN Protein phosphatase 1 regulatory subunit 42 (sprot)

description: A protein phosphatase 1 regulatory subunit 42 that is encoded in the genome of human.


name: RE114_HUMAN Meiotic recombination protein REC114 (sprot)

description: A meiotic recombination protein REC114 that is encoded in the genome of human.


name: TRPM1_HUMAN Transient receptor potential cation channel subfamily M member 1 (sprot)

description: A transient receptor potential cation channel subfamily M member 1 that is encoded in the genome of human.


name: P4HA3_HUMAN Prolyl 4-hydroxylase subunit alpha-3 (sprot)

description: A prolyl 4-hydroxylase subunit alpha-3 that is encoded in the genome of human.


name: GDF7_HUMAN Growth/differentiation factor 7 (sprot)

description: A growth/differentiation factor 7 that is encoded in the genome of human.


roof plate formation

description: The formation of a single row of glia at the dorsal midline of the developing neural tube. This region provides inductive signals for the specification of neuronal cell types and of the specification of neural crest cells. The cells comprising the roof plate are the precursors to radial glial cells.


name: positive regulation of tendon cell differentiation

description: Any process that activates or increases the frequency, rate or extent of tendon cell differentiation.


name: HEAT3_HUMAN HEAT repeat-containing protein 3 (sprot)

description: A HEAT repeat-containing protein 3 that is encoded in the genome of human.


name: CF120_HUMAN UPF0669 protein C6orf120 (sprot)

description: A UPF0669 protein C6orf120 that is encoded in the genome of human.


name: KI21A_HUMAN Kinesin-like protein KIF21A (sprot)

description: A kinesin-like protein KIF21A that is encoded in the genome of human.


name: GLTL5_HUMAN Inactive polypeptide N-acetylgalactosaminyltransferase-like protein 5 (sprot)

description: A polypeptide N-acetylgalactosaminyltransferase-like protein 5 that is encoded in the genome of human.


name: CFA91_HUMAN Cilia- and flagella-associated protein 91 (sprot)

description: A cilia- and flagella-associated protein 91 that is encoded in the genome of human.


radial spoke stalk

description: Protein complex forming the elongated portion of the radial spoke between the base which binds to the A-tubule of each microtubule outer doublet and the neck which connects to the spoke head within the ciliary or flagellum axoneme.


name: ZN438_HUMAN Zinc finger protein 438 (sprot)

description: A zinc finger protein 438 that is encoded in the genome of human.


name: HDGR2_HUMAN Hepatoma-derived growth factor-related protein 2 (sprot)

description: A hepatoma-derived growth factor-related protein 2 that is encoded in the genome of human.


H3K9me3 modified histone binding

description: Binding to a histone H3 in which the lysine residue at position 9 has been modified by trimethylation.


DCXR_HUMAN L-xylulose reductase (sprot)

An L-xylulose reductase that is encoded in the genome of human.


L-xylulose reductase (NADPH) activity

description: Catalysis of the reaction: NADP+ + xylitol = L-xylulose + H+ + NADPH.


name: LYZL2_HUMAN Lysozyme-like protein 2 (sprot)

description: A lysozyme-like protein 2 that is encoded in the genome of human.


name: KR193_HUMAN Keratin-associated protein 19-3 (sprot)

description: A keratin-associated protein 19-3 that is encoded in the genome of human.


name: AT5L2_HUMAN Putative ATP synthase subunit g 2, mitochondrial (sprot)

description: A putative ATP synthase subunit g 2, mitochondrial that is encoded in the genome of human.


name: MDGA2_HUMAN MAM domain-containing glycosylphosphatidylinositol anchor protein 2 (sprot)

description: A MAM domain-containing glycosylphosphatidylinositol anchor protein 2 that is encoded in the genome of human.


name: BRAP_HUMAN BRCA1-associated protein (sprot)

description: A BRCA1-associated protein that is encoded in the genome of human.


name: Z804A_HUMAN Zinc finger protein 804A (sprot)

description: A zinc finger protein 804A that is encoded in the genome of human.


name: SPT21_HUMAN Spermatogenesis-associated protein 21 (sprot)

description: A spermatogenesis-associated protein 21 that is encoded in the genome of human.


name: EMSY_HUMAN BRCA2-interacting transcriptional repressor EMSY (sprot)

description: A transcriptional repressor EMSY that is encoded in the genome of human.


name: AKNA_HUMAN Microtubule organization protein AKNA (sprot)

description: A microtubule organization protein AKNA that is encoded in the genome of human.


delamination

description: The process of negative regulation of cell adhesion that results in a cell or sheet of cells splitting off from an existing epithelial sheet.


neuroblast delamination

description: The negative regulation of cell adhesion process in which a neuroblast splits off of a neurectodermal sheet.


name: PRS42_HUMAN Putative serine protease 42 (sprot)

description: A putative serine protease 42 that is encoded in the genome of human.


name: TAFA5_HUMAN Chemokine-like protein TAFA-5 (sprot)

description: A chemokine-like protein TAFA-5 that is encoded in the genome of human.


name: TAFA3_HUMAN Chemokine-like protein TAFA-3 (sprot)

description: A chemokine-like protein TAFA-3 that is encoded in the genome of human.


name: TAFA1_HUMAN Chemokine-like protein TAFA-1 (sprot)

description: A chemokine-like protein TAFA-1 that is encoded in the genome of human.


RIC3_HUMAN Protein RIC-3 (sprot)

A protein RIC-3 that is encoded in the genome of human.


name: NANGN_HUMAN NANOG neighbor homeobox (sprot)

description: A NANOG neighbor homeobox that is encoded in the genome of human.


name: GOGA7_HUMAN Golgin subfamily A member 7 (sprot)

description: A golgin subfamily A member 7 that is encoded in the genome of human.


palmitoyltransferase complex

description: A protein complex with palmitoyltransferase activity.


name: RHG22_HUMAN Rho GTPase-activating protein 22 (sprot)

description: A Rho GTPase-activating protein 22 that is encoded in the genome of human.


name: VN1R5_HUMAN Vomeronasal type-1 receptor 5 (sprot)

description: A vomeronasal type-1 receptor 5 that is encoded in the genome of human.


pheromone receptor activity

description: Combining with a pheromone to initiate a change in cell activity. A pheromone is a substance used in olfactory communication between organisms of the same species eliciting a change in sexual or social behavior.


response to pheromone

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pheromone stimulus.


name: VN1R4_HUMAN Vomeronasal type-1 receptor 4 (sprot)

description: A vomeronasal type-1 receptor 4 that is encoded in the genome of human.


name: DHI1L_HUMAN Hydroxysteroid 11-beta-dehydrogenase 1-like protein (sprot)

description: A hydroxysteroid 11-beta-dehydrogenase 1-like protein that is encoded in the genome of human.


name: RAI1_HUMAN Retinoic acid-induced protein 1 (sprot)

description: A retinoic acid-induced protein 1 that is encoded in the genome of human.


name: ANKAR_HUMAN Ankyrin and armadillo repeat-containing protein (sprot)

description: An ankyrin and armadillo repeat-containing protein that is encoded in the genome of human.


name: WAPL_HUMAN Wings apart-like protein homolog (sprot)

description: A wings apart-like protein that is encoded in the genome of human.


name: ATP-dependent protein-DNA unloader activity

description: Facilitating the removal of a protein or protein complex from a DNA molecule driven by ATP hydrolysis. This can be achieved for example by introducing non-canonical DNA structures or generating torque to directly inhibit a protein-DNA binding interaction.


name: VMO1_HUMAN Vitelline membrane outer layer protein 1 homolog (sprot)

description: A vitelline membrane outer layer protein 1 that is encoded in the genome of human.


name: R3HCL_HUMAN Coiled-coil domain-containing protein R3HCC1L (sprot)

description: A coiled-coil domain-containing protein R3HCC1L that is encoded in the genome of human.


name: C1QL2_HUMAN Complement C1q-like protein 2 (sprot)

description: A complement C1q-like protein 2 that is encoded in the genome of human.


name: SPT19_HUMAN Spermatogenesis-associated protein 19, mitochondrial (sprot)

description: A spermatogenesis-associated protein 19, mitochondrial that is encoded in the genome of human.


sperm mitochondrion organization

description: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of sperm mitochondria; the process in which they take on their characteristic morphology; they are flattened, elongated, and arranged circumferentially into a tight helical coil around the tail-dense fibers of the mature sperm.


PODN_HUMAN Podocan (sprot)

A podocan that is encoded in the genome of human.


name: I2BP2_HUMAN Interferon regulatory factor 2-binding protein 2 (sprot)

description: An interferon regulatory factor 2-binding protein 2 that is encoded in the genome of human.


name: TMC3_HUMAN Transmembrane channel-like protein 3 (sprot)

description: A transmembrane channel-like protein 3 that is encoded in the genome of human.


SDK1_HUMAN Protein sidekick-1 (sprot)

A protein sidekick-1 that is encoded in the genome of human.


name: DHB13_HUMAN 17-beta-hydroxysteroid dehydrogenase 13 (sprot)

description: A 17-beta-hydroxysteroid dehydrogenase 13 that is encoded in the genome of human.


MUC19_HUMAN Mucin-19 (sprot)

A mucin-19 that is encoded in the genome of human.


name: CPEB2_HUMAN Cytoplasmic polyadenylation element-binding protein 2 (sprot)

description: A cytoplasmic polyadenylation element-binding protein 2 that is encoded in the genome of human.


name: negative regulation of cytoplasmic translational elongation

description: Any process that stops, prevents or reduces the frequency, rate or extent of cytoplasmic translational elongation.


DPOLN_HUMAN DNA polymerase nu (sprot)

A DNA polymerase nu that is encoded in the genome of human.


name: AB1IP_HUMAN Amyloid beta A4 precursor protein-binding family B member 1-interacting protein (sprot)

description: An amyloid beta A4 precursor protein-binding family B member 1-interacting protein that is encoded in the genome of human.


name: TM144_HUMAN Transmembrane protein 144 (sprot)

description: A transmembrane protein 144 that is encoded in the genome of human.


name: SAXO4_HUMAN Stabilizer of axonemal microtubules 4 (sprot)

description: A stabilizer of axonemal microtubules 4 that is encoded in the genome of human.


name: BN3D2_HUMAN RNA 5'-monophosphate methyltransferase (sprot)

description: A methyltransferase BCDIN3D that is encoded in the genome of human.


name: BMP8A_HUMAN Bone morphogenetic protein 8A (sprot)

description: A bone morphogenetic protein 8A that is encoded in the genome of human.


name: KCD20_HUMAN BTB/POZ domain-containing protein KCTD20 (sprot)

description: A BTB/POZ domain-containing protein KCTD20 that is encoded in the genome of human.


name: GP142_HUMAN Probable G-protein coupled receptor 142 (sprot)

description: A probable G-protein coupled receptor 142 that is encoded in the genome of human.


name: GP141_HUMAN Probable G-protein coupled receptor 141 (sprot)

description: A probable G-protein coupled receptor 141 that is encoded in the genome of human.


SNX20_HUMAN Sorting nexin-20 (sprot)

A sorting nexin-20 that is encoded in the genome of human.


name: CMKMT_HUMAN Calmodulin-lysine N-methyltransferase (sprot)

description: A calmodulin-lysine N-methyltransferase that is encoded in the genome of human.


description: Catalysis of the reaction: S-adenosyl-L-methionine + calmodulin L-lysine = S-adenosyl-L-homocysteine + calmodulin N6-methyl-L-lysine.


name: ARHG8_HUMAN Neuroepithelial cell-transforming gene 1 protein (sprot)

description: A neuroepithelial cell-transforming gene 1 protein that is encoded in the genome of human.


name: CEA19_HUMAN Carcinoembryonic antigen-related cell adhesion molecule 19 (sprot)

description: A carcinoembryonic antigen-related cell adhesion molecule 19 that is encoded in the genome of human.


name: ADCK2_HUMAN Uncharacterized aarF domain-containing protein kinase 2 (sprot)

description: An uncharacterized aarF domain-containing protein kinase 2 that is encoded in the genome of human.


name: regulation of ubiquinone biosynthetic process

description: Any process that modulates the frequency, rate or extent of ubiquinone biosynthesis. Ubiquinone biosynthesis consists of the chemical reactions and pathways resulting in the formation of ubiquinone, a lipid-soluble electron-transporting coenzyme.


name: SPRE2_HUMAN Sprouty-related, EVH1 domain-containing protein 2 (sprot)

description: A sprouty-related, EVH1 domain-containing protein 2 that is encoded in the genome of human.


stem cell factor receptor binding

description: Binding to a stem cell factor receptor (SCFR), a type III transmembrane kinase receptor.


regulation of protein deacetylation

description: Any process that modulates the rate, frequency, or extent of protein deacetylation, the removal of an acetyl group from a protein amino acid. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid.


name: SPRE1_HUMAN Sprouty-related, EVH1 domain-containing protein 1 (sprot)

description: A sprouty-related, EVH1 domain-containing protein 1 that is encoded in the genome of human.


name: BTLA_HUMAN B- and T-lymphocyte attenuator (sprot)

description: A B- and T-lymphocyte attenuator that is encoded in the genome of human.


name: CCD91_HUMAN Coiled-coil domain-containing protein 91 (sprot)

description: A coiled-coil domain-containing protein 91 that is encoded in the genome of human.


name: SRGP1_HUMAN SLIT-ROBO Rho GTPase-activating protein 1 (sprot)

description: A SLIT-ROBO Rho GTPase-activating protein 1 that is encoded in the genome of human.


name: RBBP6_HUMAN E3 ubiquitin-protein ligase RBBP6 (sprot)

description: An E3 ubiquitin-protein ligase RBBP6 that is encoded in the genome of human.


name: NECA2_HUMAN N-terminal EF-hand calcium-binding protein 2 (sprot)

description: An N-terminal EF-hand calcium-binding protein 2 that is encoded in the genome of human.


name: negative regulation of G protein-coupled receptor internalization

description: Any process that stops, prevents or reduces the frequency, rate or extent of G protein-coupled receptor internalization.


name: ANS1B_HUMAN Ankyrin repeat and sterile alpha motif domain-containing protein 1B (sprot)

description: An ankyrin repeat and sterile alpha motif domain-containing protein 1B that is encoded in the genome of human.


name: SPT12_HUMAN Spermatogenesis-associated protein 12 (sprot)

description: A spermatogenesis-associated protein 12 that is encoded in the genome of human.


name: RHG30_HUMAN Rho GTPase-activating protein 30 (sprot)

description: A Rho GTPase-activating protein 30 that is encoded in the genome of human.


name: CE024_HUMAN UPF0461 protein C5orf24 (sprot)

description: A UPF0461 protein C5orf24 that is encoded in the genome of human.


name: SH3R1_HUMAN E3 ubiquitin-protein ligase SH3RF1 (sprot)

description: An E3 ubiquitin-protein ligase SH3RF1 that is encoded in the genome of human.


name: regulation of CD4-positive, alpha-beta T cell differentiation

description: Any process that modulates the frequency, rate, or extent of CD4-positive, alpha-beta T cell differentiation.


GRASP_HUMAN Protein TAMALIN (sprot)

A protein TAMALIN that is encoded in the genome of human.


name: FGD2_HUMAN FYVE, RhoGEF and PH domain-containing protein 2 (sprot)

description: A FYVE, RhoGEF and PH domain-containing protein 2 that is encoded in the genome of human.


name: FRMD5_HUMAN FERM domain-containing protein 5 (sprot)

description: A FERM domain-containing protein 5 that is encoded in the genome of human.


name: UBE3D_HUMAN E3 ubiquitin-protein ligase E3D (sprot)

description: An E3 ubiquitin-protein ligase E3D that is encoded in the genome of human.


name: SEN54_HUMAN tRNA-splicing endonuclease subunit Sen54 (sprot)

description: A tRNA-splicing endonuclease subunit Sen54 that is encoded in the genome of human.


name: THAP5_HUMAN THAP domain-containing protein 5 (sprot)

description: A THAP domain-containing protein 5 that is encoded in the genome of human.


name: PTAR1_HUMAN Protein prenyltransferase alpha subunit repeat-containing protein 1 (sprot)

description: A protein prenyltransferase alpha subunit repeat-containing protein 1 that is encoded in the genome of human.


protein prenyltransferase activity

description: Catalysis of the covalent addition of an isoprenoid group such as a farnesyl or geranylgeranyl group via thioether linkages to a cysteine residue in a protein.


name: NRARP_HUMAN Notch-regulated ankyrin repeat-containing protein (sprot)

description: A notch-regulated ankyrin repeat-containing protein that is encoded in the genome of human.


ARPIN_HUMAN Arpin (sprot)

An arpin that is encoded in the genome of human.


name: PRRT2_HUMAN Proline-rich transmembrane protein 2 (sprot)

description: A proline-rich transmembrane protein 2 that is encoded in the genome of human.


name: negative regulation of SNARE complex assembly

description: Any process that decreases the frequency, rate or extent of assembly of the SNARE complex. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers.


name: negative regulation of short-term synaptic potentiation

description: Any process that stops, prevents or reduces the frequency, rate or extent of short-term synaptic potentiation.


name: TCPR1_HUMAN Tectonin beta-propeller repeat-containing protein 1 (sprot)

description: A tectonin beta-propeller repeat-containing protein 1 that is encoded in the genome of human.


name: RABEK_HUMAN Rab9 effector protein with kelch motifs (sprot)

description: A Rab9 effector protein with Kelch motifs that is encoded in the genome of human.


name: FBX33_HUMAN F-box only protein 33 (sprot)

description: An F-box only protein 33 that is encoded in the genome of human.


MILR1_HUMAN Allergin-1 (sprot)

An allergin-1 that is encoded in the genome of human.


name: MTEF4_HUMAN Transcription termination factor 4, mitochondrial (sprot)

description: A transcription termination factor 4, mitochondrial that is encoded in the genome of human.


name: RAB44_HUMAN Ras-related protein Rab-44 (sprot)

description: A Ras-related protein Rab-44 that is encoded in the genome of human.


name: histamine secretion mediated by IgE immunoglobulin

description: Histamine release triggered by the binding of an antigen to an IgE immunoglobulin bound to the cell surface. An example is mast cell histamine degranulation as a result of exposure of mast cell-bound IgE to alder tree pollen.


name: AP2D_HUMAN Transcription factor AP-2-delta (sprot)

description: A transcription factor AP-2-delta that is encoded in the genome of human.


inferior colliculus development

description: The process whose specific outcome is the progression of the inferior colliculus over time, from its formation to the mature structure. The inferior colliculus (IC) (Latin, lower hill) is the principal midbrain nucleus of the auditory pathway and receives input from several more peripheral brainstem nuclei in the auditory pathway, as well as inputs from the auditory cortex. The inferior colliculus has three subdivisions: the central nucleus (CIC), a dorsal cortex (DCIC) by which it is surrounded, and an external cortex (ICX) which is located laterally.


name: ADAT2_HUMAN tRNA-specific adenosine deaminase 2 (sprot)

description: A tRNA-specific adenosine deaminase 2 that is encoded in the genome of human.


name: TMCO2_HUMAN Transmembrane and coiled-coil domain-containing protein 2 (sprot)

description: A transmembrane and coiled-coil domain-containing protein 2 that is encoded in the genome of human.


name: DNJB7_HUMAN DnaJ homolog subfamily B member 7 (sprot)

description: A DnaJ homolog subfamily B member 7 that is encoded in the genome of human.


name: PLPL5_HUMAN Patatin-like phospholipase domain-containing protein 5 (sprot)

description: A patatin-like phospholipase domain-containing protein 5 that is encoded in the genome of human.


name: HUWE1_HUMAN E3 ubiquitin-protein ligase HUWE1 (sprot)

description: An E3 ubiquitin-protein ligase HUWE1 that is encoded in the genome of human.


histone ubiquitin ligase activity

description: Catalysis of the transfer of ubiquitin to a histone substrate.


name: ANR37_HUMAN Ankyrin repeat domain-containing protein 37 (sprot)

description: An ankyrin repeat domain-containing protein 37 that is encoded in the genome of human.


name: PKHH3_HUMAN Pleckstrin homology domain-containing family H member 3 (sprot)

description: A pleckstrin homology domain-containing family H member 3 that is encoded in the genome of human.


name: YTHD3_HUMAN YTH domain-containing family protein 3 (sprot)

description: A YTH domain-containing family protein 3 that is encoded in the genome of human.


name: MRO2B_HUMAN Maestro heat-like repeat-containing protein family member 2B (sprot)

description: A maestro heat-like repeat-containing protein family member 2B that is encoded in the genome of human.


name: S35E3_HUMAN Solute carrier family 35 member E3 (sprot)

description: A solute carrier family 35 member E3 that is encoded in the genome of human.


description: The directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


carbohydrate derivative transport

description: The directed movement of a carbohydrate derivative into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


name: K2C1B_HUMAN Keratin, type II cytoskeletal 1b (sprot)

description: A keratin, type II cytoskeletal 1b that is encoded in the genome of human.


CNTRL_HUMAN Centriolin (sprot)

A centriolin that is encoded in the genome of human.


meiotic spindle pole

description: Either of the ends of a meiotic spindle, a spindle that forms as part of meiosis, where spindle microtubules are organized; usually contains a microtubule organizing center and accessory molecules, spindle microtubules and astral microtubules.


name: CTU1_HUMAN Cytoplasmic tRNA 2-thiolation protein 1 (sprot)

description: A cytoplasmic tRNA 2-thiolation protein 1 that is encoded in the genome of human.


name: PXK_HUMAN PX domain-containing protein kinase-like protein (sprot)

description: A PX domain-containing protein kinase-like protein that is encoded in the genome of human.


name: FLIP1_HUMAN Filamin-A-interacting protein 1 (sprot)

description: A filamin-A-interacting protein 1 that is encoded in the genome of human.


name: PIGW_HUMAN Phosphatidylinositol-glycan biosynthesis class W protein (sprot)

description: A phosphatidylinositol-glycan biosynthesis class W protein that is encoded in the genome of human.


GPI anchor metabolic process

description: The chemical reactions and pathways involving glycosylphosphatidylinositol anchors, molecular mechanisms for attaching membrane proteins to the lipid bilayer of cell membranes. Structurally they consist of a molecule of phosphatidylinositol to which is linked, via the C-6 hydroxyl of the inositol, a carbohydrate chain. This chain is in turn linked to the protein through an ethanolamine phosphate group, the amino group of which is in amide linkage with the C-terminal carboxyl of the protein chain, the phosphate group being esterified to the C-6 hydroxyl of the terminal mannose of the core carbohydrate chain.


DB132_HUMAN Beta-defensin 132 (sprot)

A beta-defensin 132 that is encoded in the genome of human.


DB128_HUMAN Beta-defensin 128 (sprot)

A beta-defensin 128 that is encoded in the genome of human.


name: STRA8_HUMAN Stimulated by retinoic acid gene 8 protein homolog (sprot)

description: A stimulated by retinoic acid gene 8 protein that is encoded in the genome of human.


name: TAF8_HUMAN Transcription initiation factor TFIID subunit 8 (sprot)

description: A transcription initiation factor TFIID subunit 8 that is encoded in the genome of human.


name: DNA-templated transcription open complex formation

description: Any process involved in the melting of the DNA hybrid of the core promoter region within the transcriptional closed complex of an RNA polymerase preinitiation complex (PIC) to produce an open complex where the DNA duplex around the transcription initiation site is unwound to form the transcription bubble.


name: VTCN1_HUMAN V-set domain-containing T-cell activation inhibitor 1 (sprot)

description: A V-set domain-containing T-cell activation inhibitor 1 that is encoded in the genome of human.


name: UB2Q1_HUMAN Ubiquitin-conjugating enzyme E2 Q1 (sprot)

description: A ubiquitin-conjugating enzyme E2 Q1 that is encoded in the genome of human.


reproductive system development

description: The progression of the reproductive system over time from its formation to the mature structure. The reproductive system consists of the organs that function in reproduction.


name: KHDC4_HUMAN KH homology domain-containing protein 4 (sprot)

description: A KH homology domain-containing protein 4 that is encoded in the genome of human.


name: RM55_HUMAN Large ribosomal subunit protein mL55 (sprot)

description: A large ribosomal subunit protein mL55 that is encoded in the genome of human.


TARSH_HUMAN Target of Nesh-SH3 (sprot)

A target of Nesh-SH3 that is encoded in the genome of human.


name: CLNK_HUMAN Cytokine-dependent hematopoietic cell linker (sprot)

description: A cytokine-dependent hematopoietic cell linker that is encoded in the genome of human.


CPLX4_HUMAN Complexin-4 (sprot)

A complexin-4 that is encoded in the genome of human.


name: VP13B_HUMAN Intermembrane lipid transfer protein VPS13B (sprot)

description: An intermembrane lipid transfer protein VPS13B that is encoded in the genome of human.


slow endocytic recycling

description: The directed movement of membrane-bounded vesicles from deep (non-peripheral) compartments endocytic compartments back to the plasma membrane where they are recycled for further rounds of transport.


name: CATIP_HUMAN Ciliogenesis-associated TTC17-interacting protein (sprot)

description: A ciliogenesis-associated TTC17-interacting protein that is encoded in the genome of human.


name: TMED4_HUMAN Transmembrane emp24 domain-containing protein 4 (sprot)

description: A transmembrane emp24 domain-containing protein 4 that is encoded in the genome of human.


name: RM10_HUMAN Large ribosomal subunit protein uL10m (sprot)

description: A large ribosomal subunit protein uL10m that is encoded in the genome of human.


name: DPPA2_HUMAN Developmental pluripotency-associated protein 2 (sprot)

description: A developmental pluripotency-associated protein 2 that is encoded in the genome of human.


name: LHPL4_HUMAN LHFPL tetraspan subfamily member 4 protein (sprot)

description: An LHFPL tetraspan subfamily member 4 protein that is encoded in the genome of human.


name: regulation of inhibitory synapse assembly

description: Any process that modulates the frequency, rate or extent of inhibitory synapse assembly.


name: CK2N1_HUMAN Calcium/calmodulin-dependent protein kinase II inhibitor 1 (sprot)

description: A calcium/calmodulin-dependent protein kinase II inhibitor 1 that is encoded in the genome of human.


name: COXM1_HUMAN COX assembly mitochondrial protein homolog (sprot)

description: A COX assembly mitochondrial protein that is encoded in the genome of human.


name: ZN467_HUMAN Zinc finger protein 467 (sprot)

description: A zinc finger protein 467 that is encoded in the genome of human.


name: CENPV_HUMAN Centromere protein V (sprot)

description: A centromere protein V that is encoded in the genome of human.


centromere complex assembly

description: The aggregation, arrangement and bonding together of proteins and centromeric DNA molecules to form a centromeric protein-DNA complex. Includes the formation of the chromatin structures which form a platform for the kinetochore, and assembly of the kinetochore onto this specialized chromatin. In fission yeast and higher eukaryotes this process also includes the formation of heterochromatin at the outer repeat (pericentric) regions of the centromere.


name: SLN11_HUMAN Schlafen family member 11 (sprot)

description: A Schlafen family member 11 that is encoded in the genome of human.


replication fork arrest

description: Any process that stops, prevents, or reduces the frequency, rate or extent of DNA replication by impeding the progress of the DNA replication fork. Replication fork arrest is one of the 'quality control' processes ensuring that DNA-dependent DNA replication occurs correctly. DNA replication fork arrest during DNA-dependent DNA replication is not known to occur outside of cases where a replication error needs to be prevented or corrected.


name: ZER1_HUMAN Protein zer-1 homolog (sprot)

description: A protein zer-1 that is encoded in the genome of human.


name: ZSCA2_HUMAN Zinc finger and SCAN domain-containing protein 2 (sprot)

description: A zinc finger and SCAN domain-containing protein 2 that is encoded in the genome of human.


name: MEGF8_HUMAN Multiple epidermal growth factor-like domains protein 8 (sprot)

description: A multiple epidermal growth factor-like domains protein 8 that is encoded in the genome of human.


name: epiboly involved in gastrulation with mouth forming second

description: The expansion of one cell sheet over other cells involved in deuterostomic gastrulation.


name: AGRD2_HUMAN Adhesion G-protein coupled receptor D2 (sprot)

description: An adhesion G-protein coupled receptor D2 that is encoded in the genome of human.


name: B3GN8_HUMAN UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8 (sprot)

description: A UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8 that is encoded in the genome of human.


description: Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + protein = UDP + 4-N-(N-acetyl-D-glucosaminyl)-protein.


name: GALT5_HUMAN Polypeptide N-acetylgalactosaminyltransferase 5 (sprot)

description: A polypeptide N-acetylgalactosaminyltransferase 5 that is encoded in the genome of human.


name: T179B_HUMAN Transmembrane protein 179B (sprot)

description: A transmembrane protein 179B that is encoded in the genome of human.


name: RALYL_HUMAN RNA-binding Raly-like protein (sprot)

description: An RNA-binding Raly-like protein that is encoded in the genome of human.


NPM2_HUMAN Nucleoplasmin-2 (sprot)

A nucleoplasmin-2 that is encoded in the genome of human.


name: PCGF5_HUMAN Polycomb group RING finger protein 5 (sprot)

description: A Polycomb group RING finger protein 5 that is encoded in the genome of human.


name: GALT7_HUMAN N-acetylgalactosaminyltransferase 7 (sprot)

description: An N-acetylgalactosaminyltransferase 7 that is encoded in the genome of human.


name: ANR23_HUMAN Ankyrin repeat domain-containing protein 23 (sprot)

description: An ankyrin repeat domain-containing protein 23 that is encoded in the genome of human.


name: DAZ4_HUMAN Deleted in azoospermia protein 4 (sprot)

description: A deleted in azoospermia protein 4 that is encoded in the genome of human.


S1A7A_HUMAN Protein S100-A7A (sprot)

A protein S100-A7A that is encoded in the genome of human.


name: NEK8_HUMAN Serine/threonine-protein kinase Nek8 (sprot)

description: A serine/threonine-protein kinase Nek8 that is encoded in the genome of human.


name: LYG2_HUMAN Lysozyme g-like protein 2 (sprot)

description: A lysozyme g-like protein 2 that is encoded in the genome of human.


name: ZAR1_HUMAN Zygote arrest protein 1 (sprot)

description: A zygote arrest protein 1 that is encoded in the genome of human.


name: PRNT_HUMAN Putative testis-specific prion protein (sprot)


name: CEI_HUMAN Putative uncharacterized protein IRX2-DT (sprot)


name: AMGO2_HUMAN Amphoterin-induced protein 2 (sprot)

description: An amphoterin-induced protein 2 that is encoded in the genome of human.


DSG4_HUMAN Desmoglein-4 (sprot)

A desmoglein-4 that is encoded in the genome of human.


name: SCD5_HUMAN Stearoyl-CoA desaturase 5 (sprot)

description: A stearoyl-CoA desaturase 5 that is encoded in the genome of human.


name: GP149_HUMAN Probable G-protein coupled receptor 149 (sprot)

description: A probable G-protein coupled receptor 149 that is encoded in the genome of human.


negative regulation of ovulation

description: Any process that stops, prevents, or reduces the frequency, rate or extent of ovulation, the release of a mature ovum/oocyte from an ovary.


name: PHLB2_HUMAN Pleckstrin homology-like domain family B member 2 (sprot)

description: A pleckstrin homology-like domain family B member 2 that is encoded in the genome of human.


name: AGRE4_HUMAN Putative adhesion G protein-coupled receptor E4P (sprot)


name: AGRG6_HUMAN Adhesion G-protein coupled receptor G6 (sprot)

description: An adhesion G-protein coupled receptor G6 that is encoded in the genome of human.


name: AGRA1_HUMAN Adhesion G protein-coupled receptor A1 (sprot)

description: An adhesion G protein-coupled receptor A1 that is encoded in the genome of human.


name: SDCG8_HUMAN Serologically defined colon cancer antigen 8 (sprot)

description: A serologically defined colon cancer antigen 8 that is encoded in the genome of human.


name: DHDDS_HUMAN Dehydrodolichyl diphosphate synthase complex subunit DHDDS (sprot)

description: A dehydrodolichyl diphosphate synthase complex subunit DHDDS that is encoded in the genome of human.


polyprenyltransferase activity

description: Catalysis of the transfer of multiple prenyl groups from one compound (donor) to another (acceptor).


name: dehydrodolichyl diphosphate synthase activity

description: Catalysis of the condensation of isopentenyl diphosphate and farnesyl diphosphate in the cis-configuration to form dehydrodolichyl diphosphate.


name: dolichyl diphosphate biosynthetic process

description: The chemical reactions and pathways resulting in the formation of dolichyl diphosphate, a diphosphorylated dolichol derivative.


name: dehydrodolichyl diphosphate synthase complex

description: A protein complex which is capable of dehydrodolichyl diphosphate synthase activity.


name: GLT10_HUMAN Polypeptide N-acetylgalactosaminyltransferase 10 (sprot)

description: A polypeptide N-acetylgalactosaminyltransferase 10 that is encoded in the genome of human.


SYT9_HUMAN Synaptotagmin-9 (sprot)

A synaptotagmin-9 that is encoded in the genome of human.


name: ILDR1_HUMAN Immunoglobulin-like domain-containing receptor 1 (sprot)

description: An immunoglobulin-like domain-containing receptor 1 that is encoded in the genome of human.


name: high-density lipoprotein particle receptor activity

description: Combining with a high-density lipoprotein particle and delivering the high-density lipoprotein into the cell via endocytosis.


tricellular tight junction assembly

description: The aggregation, arrangement and bonding together of a set of components to form a tricellular tight junction.


name: TEDC1_HUMAN Tubulin epsilon and delta complex protein 1 (sprot)

description: A tubulin epsilon and delta complex protein 1 that is encoded in the genome of human.


name: GLRX5_HUMAN Glutaredoxin-related protein 5, mitochondrial (sprot)

description: A glutaredoxin-related protein 5 that is encoded in the genome of human.


name: protein maturation by [4Fe-4S] cluster transfer

description: The transfer of an assembled 4Fe-4S] cluster from a scaffold protein to an acceptor protein that contributes to the attainment of the full functional capacity of a protein.


name: TPC6B_HUMAN Trafficking protein particle complex subunit 6B (sprot)

description: A trafficking protein particle complex subunit 6B that is encoded in the genome of human.


name: PP4P1_HUMAN Type 1 phosphatidylinositol 4,5-bisphosphate 4-phosphatase (sprot)

description: A type 1 phosphatidylinositol 4,5-bisphosphate 4-phosphatase that is encoded in the genome of human.


description: Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O = 1-phosphatidyl-1D-myo-inositol 3-phosphate + phosphate.


name: proton-transporting V-type ATPase complex assembly

description: The aggregation, arrangement and bonding together of a proton-transporting V-type ATPase complex, proton-transporting two-sector ATPase complex that couples ATP hydrolysis to the transport of protons across a concentration gradient.


name: CLC14_HUMAN C-type lectin domain family 14 member A (sprot)

description: A C-type lectin domain family 14 member A that is encoded in the genome of human.


name: vascular endothelial growth factor receptor-3 signaling pathway

category: biolink:Pathway biolink:OntologyClass biolink:BiologicalProcess biolink:Occurrent biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: The series of molecular signals initiated by a ligand binding to a vascular endothelial growth factor receptor-3 (VEGFR-3) on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.


name: SIM29_HUMAN Small integral membrane protein 29 (sprot)

description: A small integral membrane protein 29 that is encoded in the genome of human.


name: CROL1_HUMAN Putative ciliary rootlet coiled-coil protein-like 1 protein (sprot)

description: A putative ciliary rootlet coiled-coil protein-like 1 protein that is encoded in the genome of human.


name: KAISO_HUMAN Transcriptional regulator Kaiso (sprot)

description: A transcriptional regulator Kaiso that is encoded in the genome of human.


name: TM11B_HUMAN Transmembrane protease serine 11B (sprot)

description: A transmembrane protease serine 11B that is encoded in the genome of human.


name: ZN605_HUMAN Zinc finger protein 605 (sprot)

description: A zinc finger protein 605 that is encoded in the genome of human.


name: DAAM2_HUMAN Disheveled-associated activator of morphogenesis 2 (sprot)

description: A disheveled-associated activator of morphogenesis 2 that is encoded in the genome of human.


name: NBPFB_HUMAN Neuroblastoma breakpoint family member 11 (sprot)

description: A neuroblastoma breakpoint family member 11 that is encoded in the genome of human.


name: UBP37_HUMAN Ubiquitin carboxyl-terminal hydrolase 37 (sprot)

description: A ubiquitin carboxyl-terminal hydrolase 37 that is encoded in the genome of human.


K1328_HUMAN Protein hinderin (sprot)

A protein hinderin that is encoded in the genome of human.


name: RN180_HUMAN E3 ubiquitin-protein ligase RNF180 (sprot)

description: An E3 ubiquitin-protein ligase RNF180 that is encoded in the genome of human.


name: MOB3B_HUMAN MOB kinase activator 3B (sprot)

description: A MOB kinase activator 3B that is encoded in the genome of human.


name: ALPK2_HUMAN Alpha-protein kinase 2 (sprot)

description: An alpha-protein kinase 2 that is encoded in the genome of human.


name: negative regulation of Wnt signaling pathway involved in heart development

description: Any process that decreases the rate, frequency, or extent of the series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell, resulting a change in cell state that contributes to the progression of the heart over time.


name: PATL1_HUMAN Protein PAT1 homolog 1 (sprot)

description: A protein PAT1 homolog 1 that is encoded in the genome of human.


name: deadenylation-dependent decapping of nuclear-transcribed mRNA

description: Cleavage of the 5'-cap of a nuclear mRNA triggered by shortening of the poly(A) tail to below a minimum functional length.


MYPN_HUMAN Myopalladin (sprot)

A myopalladin that is encoded in the genome of human.


muscle alpha-actinin binding

description: Binding to muscle isoforms of actinin. Muscle alpha-actinin isoforms are found in skeletal and cardiac muscle and are localized to the Z-disc.


SRCA_HUMAN Sarcalumenin (sprot)

A sarcalumenin that is encoded in the genome of human.


name: LUZP2_HUMAN Leucine zipper protein 2 (sprot)

description: A leucine zipper protein 2 that is encoded in the genome of human.


name: T150A_HUMAN Transmembrane protein 150A (sprot)

description: A transmembrane protein 150A that is encoded in the genome of human.


name: PEG10_HUMAN Retrotransposon-derived protein PEG10 (sprot)

description: A retrotransposon-derived protein PEG10 that is encoded in the genome of human.


name: ATL2_HUMAN ADAMTS-like protein 2 (sprot)

description: An ADAMTS-like protein 2 that is encoded in the genome of human.


lobar bronchus epithelium development

description: The biological process whose specific outcome is the progression of a lobar bronchus epithelium from an initial condition to its mature state. This process begins with the formation of the lobar bronchus epithelium and ends with the mature structure. The lobar bronchus epithelium is the tissue made up of epithelial cells that lines the inside of the lobar bronchus.


name: TBCD1_HUMAN TBC1 domain family member 1 (sprot)

description: A TBC1 domain family member 1 that is encoded in the genome of human.


name: DPP9_HUMAN Dipeptidyl peptidase 9 (sprot)

description: A dipeptidyl peptidase 9 that is encoded in the genome of human.


name: TAD2B_HUMAN Transcriptional adapter 2-beta (sprot)

description: A transcriptional adapter 2-beta that is encoded in the genome of human.


SAGA-type complex

description: A histone acetyltransferase complex that acetylates nucleosomal histones H2B, H3, or H4 and is required for the expression of a subset of Pol II-transcribed genes. This complex includes the acetyltransferases GCN5/KAT2A or PCAF/KAT2B, several proteins of the ADA, SGF and SPT families, and several TBP-associate proteins (TAFs).


name: ZN554_HUMAN Zinc finger protein 554 (sprot)

description: A zinc finger protein 554 that is encoded in the genome of human.


name: ATG4D_HUMAN Cysteine protease ATG4D (sprot)

description: A cysteine protease ATG4D that is encoded in the genome of human.


protein delipidation

description: The breakage of covalent bonds to detach lipid groups from a protein.


name: STIMA_HUMAN Store-operated calcium entry regulator STIMATE (sprot)

description: A store-operated calcium entry regulator STIMATE that is encoded in the genome of human.


name: DDX53_HUMAN Probable ATP-dependent RNA helicase DDX53 (sprot)

description: A probable ATP-dependent RNA helicase DDX53 that is encoded in the genome of human.


name: SYVN1_HUMAN E3 ubiquitin-protein ligase synoviolin (sprot)

description: An E3 ubiquitin-protein ligase synoviolin that is encoded in the genome of human.


Hrd1p ubiquitin ligase ERAD-L complex

description: A multiprotein complex that recognizes and ubiquitinates proteins with misfolded luminal domains during ER-associated protein degradation (ERAD). In S. cerevisiae, this complex contains the ubiquitin ligase Hrd1p.


name: TRPT1_HUMAN tRNA 2'-phosphotransferase 1 (sprot)

description: A tRNA 2'-phosphotransferase 1 that is encoded in the genome of human.


name: PRUN1_HUMAN Exopolyphosphatase PRUNE1 (sprot)

description: An exopolyphosphatase PRUNE1 that is encoded in the genome of human.


name: RM52_HUMAN Large ribosomal subunit protein mL52 (sprot)

description: A large ribosomal subunit protein mL52 that is encoded in the genome of human.


name: SETD3_HUMAN Actin-histidine N-methyltransferase (sprot)

description: An actin-histidine N-methyltransferase that is encoded in the genome of human.


peptidyl-histidine methylation

description: The methylation of peptidyl-L-histidine to form peptidyl-L-1'-methyl-L-histidine (otherwise known as tau-methylhistidine, tele-methylhistidine) or peptidyl-L-3'-methyl-L-histidine (otherwise known as pi-methylhistidine, pros-methylhistidine).


actin modification

description: Covalent modification of an actin molecule.


name: regulation of uterine smooth muscle contraction

description: Any process that modulates the frequency, rate or extent of uterine smooth muscle contraction.


name: TTC7B_HUMAN Tetratricopeptide repeat protein 7B (sprot)

description: A tetratricopeptide repeat protein 7B that is encoded in the genome of human.


name: ADCK1_HUMAN AarF domain-containing protein kinase 1 (sprot)

description: An AarF domain-containing protein kinase 1 that is encoded in the genome of human.


name: positive regulation of cristae formation

description: Any process that activates or increases the frequency, rate or extent of cristae formation.


name: ACOT1_HUMAN Acyl-coenzyme A thioesterase 1 (sprot)

description: An acyl-coenzyme A thioesterase 1 that is encoded in the genome of human.


name: ARMD4_HUMAN Armadillo-like helical domain-containing protein 4 (sprot)

description: An armadillo-like helical domain-containing protein 4 that is encoded in the genome of human.


regulation of TORC2 signaling

description: Any process that modulates the frequency, rate or extent of TORC2 signaling.


name: CN165_HUMAN Putative uncharacterized protein encoded by LINC00596 (sprot)


name: RBM23_HUMAN Probable RNA-binding protein 23 (sprot)

description: A probable RNA-binding protein 23 that is encoded in the genome of human.


name: LPP60_HUMAN 60 kDa lysophospholipase (sprot)

description: A 60 kDa lysophospholipase that is encoded in the genome of human.


name: acyltransferase activity, transferring groups other than amino-acyl groups

description: Catalysis of the transfer of an acyl group, other than amino-acyl, from one compound (donor) to another (acceptor).


name: ISCA2_HUMAN Iron-sulfur cluster assembly 2 homolog, mitochondrial (sprot)

description: An iron-sulfur cluster assembly 2, mitochondrial that is encoded in the genome of human.


NOP9_HUMAN Nucleolar protein 9 (sprot)

A nucleolar protein 9 that is encoded in the genome of human.


name: PABP2_HUMAN Polyadenylate-binding protein 2 (sprot)

description: A polyadenylate-binding protein 2 (human), isoforms 1 and 2.


name: positive regulation of polynucleotide adenylyltransferase activity

description: Any process that activates or increases the frequency, rate or extent of polynucleotide adenylyltransferase activity.


name: MTA70_HUMAN N6-adenosine-methyltransferase catalytic subunit (sprot)

description: An N6-adenosine-methyltransferase catalytic subunit that is encoded in the genome of human.


mRNA m(6)A methyltransferase activity

description: Catalysis of the reaction: an adenosine in mRNA + S-adenosyl-L-methionine = an N(6)-methyladenosine in mRNA + H+ + S-adenosyl-L-homocysteine. This activity is the methylation of adenines in mRNA with the consensus sequence RRACH, where R is a purine, and H is C, A, or U.


description: Catalysis of the reaction: S-adenosyl-L-methionine + m(7)G(5')pppAm = S-adenosyl-L-homocysteine + m(7)G(5')pppm(6)Am.


name: LDB1_HUMAN LIM domain-binding protein 1 (sprot)

description: A LIM domain-binding protein 1 that is encoded in the genome of human.


name: transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery

description: The chromosome organization process in which the DNA sequence containing a gene transcribed by RNA polymerase II is maintained in a specific location at the nuclear periphery. In S. cerevisiae, this process involves cis-acting DNA sequences such as the TATA box and upstream activating sequence (UAS) elements, trans-acting transcriptional activators, and also the 3'-UTR of the transcript.


cellular component assembly

description: The aggregation, arrangement and bonding together of a cellular component.


PB1_HUMAN Protein polybromo-1 (sprot)

A protein polybromo-1 that is encoded in the genome of human.


name: YRDC_HUMAN Threonylcarbamoyl-AMP synthase (sprot)

description: A threonylcarbamoyl-AMP synthase that is encoded in the genome of human.


L-threonylcarbamoyladenylate synthase

description: Catalysis of the reaction: L-threonine + ATP + bicarbonate = L-threonylcarbamoyladenylate + diphosphate + H2O.


description: The attachment of a carbonyl group and a threonine to the amino group of the adenine residue immediately 3' of the anticodon, in tRNAs that decode ANN codons (where N is any base).


name: PRP39_HUMAN Pre-mRNA-processing factor 39 (sprot)

description: A pre-mRNA-processing factor 39 that is encoded in the genome of human.


name: RIP_HUMAN RPA-interacting protein (sprot)

description: An RPA-interacting protein that is encoded in the genome of human.


name: BIVM_HUMAN Basic immunoglobulin-like variable motif-containing protein (sprot)

description: A basic immunoglobulin-like variable motif-containing protein that is encoded in the genome of human.


name: TM135_HUMAN Transmembrane protein 135 (sprot)

description: A transmembrane protein 135 that is encoded in the genome of human.


name: RSPH3_HUMAN Radial spoke head protein 3 homolog (sprot)

description: A radial spoke head protein 3 that is encoded in the genome of human.


name: SAPC2_HUMAN Suppressor APC domain-containing protein 2 (sprot)

description: A suppressor APC domain-containing protein 2 that is encoded in the genome of human.


symmetric cell division

description: Cell division in which both daughter cells are of the same type.


name: negative regulation of protein localization to cell cortex

description: Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell cortex.


name: MARH3_HUMAN E3 ubiquitin-protein ligase MARCHF3 (sprot)

description: An E3 ubiquitin-protein ligase MARCHF3 that is encoded in the genome of human.


name: ZN329_HUMAN Zinc finger protein 329 (sprot)

description: A zinc finger protein 329 that is encoded in the genome of human.


name: SL9B2_HUMAN Sodium/hydrogen exchanger 9B2 (sprot)

description: A sodium/hydrogen exchanger 9B2 that is encoded in the genome of human.


name: lithium:proton antiporter activity

description: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Li+(in) + H+(out) = Li+(out) + H+(in).


lithium ion transport

description: The directed movement of lithium ion into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


name: ZN546_HUMAN Zinc finger protein 546 (sprot)

description: A zinc finger protein 546 that is encoded in the genome of human.


LYRIC_HUMAN Protein LYRIC (sprot)

A protein LYRIC that is encoded in the genome of human.


name: LRRT1_HUMAN Leucine-rich repeat transmembrane neuronal protein 1 (sprot)

description: A leucine-rich repeat transmembrane neuronal protein 1 that is encoded in the genome of human.


name: TLK2_HUMAN Serine/threonine-protein kinase tousled-like 2 (sprot)

description: A serine/threonine-protein kinase tousled-like 2 that is encoded in the genome of human.


TSN33_HUMAN Tetraspanin-33 (sprot)

A tetraspanin-33 that is encoded in the genome of human.


name: CTGE6_HUMAN cTAGE family member 6 (sprot)

description: A cTAGE family member 6 that is encoded in the genome of human.


name: SO6A1_HUMAN Solute carrier organic anion transporter family member 6A1 (sprot)

description: A solute carrier organic anion transporter family member 6A1 that is encoded in the genome of human.


name: ABCAC_HUMAN Glucosylceramide transporter ABCA12 (sprot)

description: A glucosylceramide transporter ABCA12 that is encoded in the genome of human.


name: positive regulation of intracellular lipid transport

description: Any process that activates or increases the frequency, rate or extent of the directed movement of lipids within cells.


epidermal lamellar body membrane

description: The lipid bilayer surrounding an epidermal lamellar body, a specialized secretory organelle found in keratinocytes and involved in the formation of an impermeable, lipid-containing membrane that serves as a water barrier and is required for correct skin barrier function.


LBN_HUMAN Limbin (sprot)

A limbin that is encoded in the genome of human.


name: ZN598_HUMAN E3 ubiquitin-protein ligase ZNF598 (sprot)

description: An E3 ubiquitin-protein ligase ZNF598 that is encoded in the genome of human.


stalled ribosome sensor activity

description: A molecule that recognizes stalled ribosomes and initiates a signaling response.


name: GPAT4_HUMAN Glycerol-3-phosphate acyltransferase 4 (sprot)

description: A glycerol-3-phosphate acyltransferase 4 that is encoded in the genome of human.


name: MAGI2_HUMAN Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (sprot)

description: A membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 that is encoded in the genome of human.


name: R4RL1_HUMAN Reticulon-4 receptor-like 1 (sprot)

description: A reticulon-4 receptor-like 1 that is encoded in the genome of human.


name: R4RL2_HUMAN Reticulon-4 receptor-like 2 (sprot)

description: A reticulon-4 receptor-like 2 that is encoded in the genome of human.


name: AKA28_HUMAN A-kinase anchor protein 14 (sprot)

description: An A-kinase anchor protein 14 that is encoded in the genome of human.


CAD24_HUMAN Cadherin-24 (sprot)

A cadherin-24 that is encoded in the genome of human.


KTN1_HUMAN Kinectin (sprot)

A kinectin that is encoded in the genome of human.


name: ZFHX4_HUMAN Zinc finger homeobox protein 4 (sprot)

description: A zinc finger homeobox protein 4 that is encoded in the genome of human.


name: CUZD1_HUMAN CUB and zona pellucida-like domain-containing protein 1 (sprot)

description: A CUB and zona pellucida-like domain-containing protein 1 that is encoded in the genome of human.


trypsinogen activation

description: The proteolytic processing of trypsinogen to the active form, trypsin.


name: GTD2A_HUMAN General transcription factor II-I repeat domain-containing protein 2A (sprot)

description: A general transcription factor II-I repeat domain-containing protein 2A that is encoded in the genome of human.


name: LHPL3_HUMAN LHFPL tetraspan subfamily member 3 protein (sprot)

description: An LHFPL tetraspan subfamily member 3 protein that is encoded in the genome of human.


name: ZN589_HUMAN Zinc finger protein 589 (sprot)

description: A zinc finger protein 589 that is encoded in the genome of human.


name: ABCAD_HUMAN ATP-binding cassette sub-family A member 13 (sprot)

description: An ATP-binding cassette sub-family A member 13 that is encoded in the genome of human.


name: GTSC1_HUMAN Gilles de la Tourette syndrome chromosomal region candidate gene 1 protein (sprot)

description: A Gilles de la Tourette syndrome chromosomal region candidate gene 1 protein that is encoded in the genome of human.


name: NFE4_HUMAN Transcription factor NF-E4 (sprot)

description: A transcription factor NF-E4 that is encoded in the genome of human.


name: NOXA1_HUMAN NADPH oxidase activator 1 (sprot)

description: An NADPH oxidase activator 1 that is encoded in the genome of human.


name: RIMS1_HUMAN Regulating synaptic membrane exocytosis protein 1 (sprot)

description: A regulating synaptic membrane exocytosis protein 1 that is encoded in the genome of human.


name: EST1A_HUMAN Telomerase-binding protein EST1A (sprot)

description: A telomerase-binding protein EST1A that is encoded in the genome of human.


regulation of dephosphorylation

description: Any process that modulates the frequency, rate or extent of removal of phosphate groups from a molecule.


name: NHRF4_HUMAN Na(+)/H(+) exchange regulatory cofactor NHE-RF4 (sprot)

description: A Na(+)/H(+) exchange regulatory cofactor NHE-RF4 that is encoded in the genome of human.


guanylate cyclase inhibitor activity

description: Binds to and stops, prevents or reduces the activity of guanylate cyclase.


name: NLRX1_HUMAN NLR family member X1 (sprot)

description: An NLR family member X1 that is encoded in the genome of human.


name: CATAC_HUMAN Centrosomal AT-AC splicing factor (sprot)

description: A centrosomal AT-AC splicing factor that is encoded in the genome of human.


name: BCL9L_HUMAN B-cell CLL/lymphoma 9-like protein (sprot)

description: A B-cell CLL/lymphoma 9-like protein that is encoded in the genome of human.


name: PHLB1_HUMAN Pleckstrin homology-like domain family B member 1 (sprot)

description: A pleckstrin homology-like domain family B member 1 that is encoded in the genome of human.


GGN_HUMAN Gametogenetin (sprot)

A gametogenetin that is encoded in the genome of human.


TKN4_HUMAN Tachykinin-4 (sprot)

A tachykinin-4 that is encoded in the genome of human.


name: UBP48_HUMAN Ubiquitin carboxyl-terminal hydrolase 48 (sprot)

description: A ubiquitin carboxyl-terminal hydrolase 48 that is encoded in the genome of human.


name: TRI74_HUMAN Tripartite motif-containing protein 74 (sprot)

description: A tripartite motif-containing protein 74 that is encoded in the genome of human.


name: TRI73_HUMAN Tripartite motif-containing protein 73 (sprot)

description: A tripartite motif-containing protein 73 that is encoded in the genome of human.


name: OSTA_HUMAN Organic solute transporter subunit alpha (sprot)

description: An organic solute transporter subunit alpha that is encoded in the genome of human.


name: OSTB_HUMAN Organic solute transporter subunit beta (sprot)

description: An organic solute transporter subunit beta that is encoded in the genome of human.


name: N4BP2_HUMAN NEDD4-binding protein 2 (sprot)

description: A NEDD4-binding protein 2 that is encoded in the genome of human.


name: CAPS2_HUMAN Calcium-dependent secretion activator 2 (sprot)

description: A calcium-dependent secretion activator 2 that is encoded in the genome of human.


dense core granule exocytosis

description: The secretion of molecules (e.g. neuropeptides, insulin-related peptides or neuromodulators such as serotonin and dopamine) contained within a membrane-bounced dense core granule by fusion of the granule with the plasma membrane of a cell in response to increased cytosolic calcium levels.


name: HPLN4_HUMAN Hyaluronan and proteoglycan link protein 4 (sprot)

description: A hyaluronan and proteoglycan link protein 4 that is encoded in the genome of human.


name: DTX2_HUMAN Probable E3 ubiquitin-protein ligase DTX2 (sprot)

description: A protein deltex-2 that is encoded in the genome of human.


name: ITIH5_HUMAN Inter-alpha-trypsin inhibitor heavy chain H5 (sprot)

description: An inter-alpha-trypsin inhibitor heavy chain H5 that is encoded in the genome of human.


name: ST32C_HUMAN Serine/threonine-protein kinase 32C (sprot)

description: A serine/threonine-protein kinase 32C that is encoded in the genome of human.


name: URP2_HUMAN Fermitin family homolog 3 (sprot)

description: A fermitin family homolog 3 that is encoded in the genome of human.


FA83A_HUMAN Protein FAM83A (sprot)

A protein FAM83A that is encoded in the genome of human.


name: NAA40_HUMAN N-alpha-acetyltransferase 40 (sprot)

description: An N-alpha-acetyltransferase 40 that is encoded in the genome of human.


histone H2A acetyltransferase activity

description: Catalysis of the reaction: acetyl-CoA + histone H2A L-lysine = CoA + histone H2A N6-acetyl-L-lysine.


description: Catalysis of the reaction: acetyl-CoA + N-terminal L-serine in peptide = CoA + N-acetyl-L-serine-peptide.


name: NT5D3_HUMAN 5'-nucleotidase domain-containing protein 3 (sprot)

description: A 5'-nucleotidase domain-containing protein 3 that is encoded in the genome of human.


name: ZBT46_HUMAN Zinc finger and BTB domain-containing protein 46 (sprot)

description: A zinc finger and BTB domain-containing protein 46 that is encoded in the genome of human.


name: CASZ1_HUMAN Zinc finger protein castor homolog 1 (sprot)

description: A zinc finger protein castor homolog 1 that is encoded in the genome of human.


name: SHLD2_HUMAN Shieldin complex subunit 2 (sprot)

description: A shieldin complex subunit 2 that is encoded in the genome of human.


name: AACS_HUMAN Acetoacetyl-CoA synthetase (sprot)

description: An acetoacetyl-CoA synthetase that is encoded in the genome of human.


acetoacetate-CoA ligase activity

description: Catalysis of the reaction: acetoacetate + ATP + CoA = acetoacetyl-CoA + AMP + diphosphate + H+.


name: PAQR2_HUMAN Adiponectin receptor protein 2 (sprot)

description: An adiponectin receptor protein 2 that is encoded in the genome of human.


name: VASH2_HUMAN Tubulinyl-Tyr carboxypeptidase 2 (sprot)

description: A tubulinyl-Tyr carboxypeptidase 2 that is encoded in the genome of human.


cell-cell fusion

description: A cellular process in which two or more cells combine together, their plasma membrane fusing, producing a single cell. In some cases, nuclei fuse, producing a polyploid cell, while in other cases, nuclei remain separate, producing a syncytium.


name: CABP7_HUMAN Calcium-binding protein 7 (sprot)

description: A calcium-binding protein 7 that is encoded in the genome of human.


name: TIKI1_HUMAN Metalloprotease TIKI1 (sprot)

description: A metalloprotease TIKI1 that is encoded in the genome of human.


F124A_HUMAN Protein FAM124A (sprot)

A protein FAM124A that is encoded in the genome of human.


name: LUZP1_HUMAN Leucine zipper protein 1 (sprot)

description: A leucine zipper protein 1 that is encoded in the genome of human.


name: ZN429_HUMAN Zinc finger protein 429 (sprot)

description: A zinc finger protein 429 that is encoded in the genome of human.


name: THOC4_HUMAN THO complex subunit 4 (sprot)

description: A THO complex subunit 4 that is encoded in the genome of human.


name: GP180_HUMAN Integral membrane protein GPR180 (sprot)

description: An integral membrane protein GPR180 that is encoded in the genome of human.


name: PIM3_HUMAN Serine/threonine-protein kinase pim-3 (sprot)

description: A serine/threonine-protein kinase Pim-3 that is encoded in the genome of human.


name: MGDP1_HUMAN Magnesium-dependent phosphatase 1 (sprot)

description: A magnesium-dependent phosphatase 1 that is encoded in the genome of human.


name: KBTB6_HUMAN Kelch repeat and BTB domain-containing protein 6 (sprot)

description: A kelch repeat and BTB domain-containing protein 6 that is encoded in the genome of human.


name: C163A_HUMAN Scavenger receptor cysteine-rich type 1 protein M130 (sprot)

description: A scavenger receptor cysteine-rich type 1 protein M130 that is encoded in the genome of human.


name: MORC1_HUMAN MORC family CW-type zinc finger protein 1 (sprot)

description: A MORC family CW-type zinc finger protein 1 that is encoded in the genome of human.


name: S2542_HUMAN Mitochondrial coenzyme A transporter SLC25A42 (sprot)

description: A solute carrier family 25 member 42 that is encoded in the genome of human.


name: PIGZ_HUMAN GPI mannosyltransferase 4 (sprot)

description: A GPI mannosyltransferase 4 that is encoded in the genome of human.


name: MYPOP_HUMAN Myb-related transcription factor, partner of profilin (sprot)

description: A Myb-related transcription factor, partner of profilin that is encoded in the genome of human.


name: SERC5_HUMAN Serine incorporator 5 (sprot)

description: A serine incorporator 5 that is encoded in the genome of human.


name: positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity

description: Any process that activates or increases the frequency, rate or extent of CDP-diacylglycerol-serine O-phosphatidyltransferase activity.


name: positive regulation of serine C-palmitoyltransferase activity

description: Any process that activates or increases the frequency, rate or extent of serine C-palmitoyltransferase activity.


name: IGFN1_HUMAN Immunoglobulin-like and fibronectin type III domain-containing protein 1 (sprot)

description: An immunoglobulin-like and fibronectin type III domain-containing protein 1 that is encoded in the genome of human.


name: MOGT3_HUMAN 2-acylglycerol O-acyltransferase 3 (sprot)

description: A 2-acylglycerol O-acyltransferase 3 that is encoded in the genome of human.


name: NRAP_HUMAN Nebulin-related-anchoring protein (sprot)

description: A nebulin-related-anchoring protein that is encoded in the genome of human.


name: IFTAP_HUMAN Intraflagellar transport-associated protein (sprot)

description: An intraflagellar transport-associated protein that is encoded in the genome of human.


name: KIF27_HUMAN Kinesin-like protein KIF27 (sprot)

description: A kinesin-like protein KIF27 that is encoded in the genome of human.


name: LRRT4_HUMAN Leucine-rich repeat transmembrane neuronal protein 4 (sprot)

description: A leucine-rich repeat transmembrane neuronal protein 4 that is encoded in the genome of human.


name: LRRT3_HUMAN Leucine-rich repeat transmembrane neuronal protein 3 (sprot)

description: A leucine-rich repeat transmembrane neuronal protein 3 that is encoded in the genome of human.


name: EX3L1_HUMAN Exocyst complex component 3-like protein (sprot)

description: An exocyst complex component 3-like protein that is encoded in the genome of human.


name: IQGA3_HUMAN Ras GTPase-activating-like protein IQGAP3 (sprot)

description: A Ras GTPase-activating-like protein IQGAP3 that is encoded in the genome of human.


myosin VI light chain binding

description: Binding to a light chain of a myosin VI complex.


name: LAP4B_HUMAN Lysosomal-associated transmembrane protein 4B (sprot)

description: A lysosomal-associated transmembrane protein 4B that is encoded in the genome of human.


name: endosome transport via multivesicular body sorting pathway

description: The directed movement of substances from endosomes to lysosomes or vacuoles by a pathway in which molecules are sorted into multivesicular bodies, which then fuse with the target compartment.


name: regulation of lysosomal membrane permeability

description: Any process that modulates the frequency, rate or extent of the passage or uptake of molecules by the lysosomal membrane.


name: ZN410_HUMAN Zinc finger protein 410 (sprot)

description: A zinc finger protein 410 that is encoded in the genome of human.


name: S47A2_HUMAN Multidrug and toxin extrusion protein 2 (sprot)

description: A multidrug and toxin extrusion protein 2 that is encoded in the genome of human.


name: polyspecific organic cation:proton antiporter activity

description: Enables the transfer of various organic cations in exchange for a proton, according to the reaction: H+(out) + organic cation(in) = H+(in) + organic cation(out). The transported substrates are usually toxic molecules, drugs and xenobiotics.