name: INT14_HUMAN Integrator complex subunit 14 (sprot)

description: An integrator complex subunit 14 that is encoded in the genome of human.


name: ZSC10_HUMAN Zinc finger and SCAN domain-containing protein 10 (sprot)

description: A zinc finger and SCAN domain-containing protein 10 that is encoded in the genome of human.


name: AEDO_HUMAN 2-aminoethanethiol dioxygenase (sprot)

description: A 2-aminoethanethiol dioxygenase that is encoded in the genome of human.


cysteamine dioxygenase activity

category: biolink:MolecularActivity biolink:Occurrent biolink:OntologyClass biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: Catalysis of the reaction: cysteamine + O2 = H+ + hypotaurine.


name: CK5P1_HUMAN Mitochondrial tRNA methylthiotransferase CDK5RAP1 (sprot)

description: A mitochondrial tRNA methylthiotransferase CDK5RAP1 that is encoded in the genome of human.


tRNA methylthiolation

category: biolink:BiologicalProcess biolink:Occurrent biolink:OntologyClass biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: The addition of a methylthioether group (-SCH3) to a nucleotide in a tRNA molecule.


name: positive regulation of translational fidelity

description: Any process that increases the ability of the translational apparatus to interpret the genetic code.


mitochondrial tRNA modification

description: The covalent alteration of one or more nucleotides within a mitochondrial tRNA molecule to produce a mitochondrial tRNA molecule with a sequence that differs from that coded genetically.


name: SEBP2_HUMAN Selenocysteine insertion sequence-binding protein 2 (sprot)

description: A selenocysteine insertion sequence-binding protein 2 that is encoded in the genome of human.


name: RSF1_HUMAN Remodeling and spacing factor 1 (sprot)

description: A remodeling and spacing factor 1 that is encoded in the genome of human.


name: ZIC5_HUMAN Zinc finger protein ZIC 5 (sprot)

description: A zinc finger protein ZIC 5 that is encoded in the genome of human.


name: RBM15_HUMAN RNA-binding protein 15 (sprot)

description: An RNA-binding protein 15 that is encoded in the genome of human.


name: PP16B_HUMAN Protein phosphatase 1 regulatory inhibitor subunit 16B (sprot)

description: A protein phosphatase 1 regulatory inhibitor subunit 16B that is encoded in the genome of human.


regulation of protein dephosphorylation

description: Any process that modulates the frequency, rate or extent of removal of phosphate groups from a protein.


name: RUFY1_HUMAN RUN and FYVE domain-containing protein 1 (sprot)

description: A RUN and FYVE domain-containing protein 1 that is encoded in the genome of human.


name: IMP2L_HUMAN Mitochondrial inner membrane protease subunit 2 (sprot)

description: A mitochondrial inner membrane protease subunit 2 that is encoded in the genome of human.


cerebellum vasculature development

description: The process whose specific outcome is the progression of the vasculature of the cerebellum over time, from its formation to the mature structure.


name: MBOA4_HUMAN Ghrelin O-acyltransferase (sprot)

description: A ghrelin O-acyltransferase that is encoded in the genome of human.


peptidyl-serine octanoylation

description: The octanoylation of peptidyl-serine to form peptidyl-O3-octanoyl-L-serine, typical of the protein ghrelin.


name: KCNKH_HUMAN Potassium channel subfamily K member 17 (sprot)

description: A potassium channel subfamily K member 17 that is encoded in the genome of human.


name: KCNKG_HUMAN Potassium channel subfamily K member 16 (sprot)

description: A potassium channel subfamily K member 16 that is encoded in the genome of human.


name: MINT_HUMAN Msx2-interacting protein (sprot)

description: An Msx2-interacting protein that is encoded in the genome of human.


name: PNKP_HUMAN Bifunctional polynucleotide phosphatase/kinase (sprot)

description: A bifunctional polynucleotide phosphatase/kinase that is encoded in the genome of human.


purine nucleotide binding

description: Binding to a purine nucleotide, a compound consisting of a purine nucleoside esterified with (ortho)phosphate.


polynucleotide 3'-phosphatase activity

description: Catalysis of the reaction: a 3'end (2'-deoxyribonucleotide 3'-phosphate)-DNA + H2O = a 3'-end 2'-deoxyribonucleotide-DNA + phosphate.


name: NMNA3_HUMAN Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 (sprot)

description: A nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 that is encoded in the genome of human.


name: SETB2_HUMAN Histone-lysine N-methyltransferase SETDB2 (sprot)

description: A histone-lysine N-methyltransferase SETDB2 that is encoded in the genome of human.


name: DSCR8_HUMAN Down syndrome critical region protein 8 (sprot)

description: A Down syndrome critical region protein 8 that is encoded in the genome of human.


name: MMS19_HUMAN MMS19 nucleotide excision repair protein homolog (sprot)

description: An MMS19 nucleotide excision repair protein that is encoded in the genome of human.


name: SL9A7_HUMAN Sodium/hydrogen exchanger 7 (sprot)

description: A sodium/hydrogen exchanger 7 that is encoded in the genome of human.


regulation of Golgi lumen acidification

description: Any process that modulates the frequency, rate or extent of Golgi lumen acidification.


name: UHRF1_HUMAN E3 ubiquitin-protein ligase UHRF1 (sprot)

description: An E3 ubiquitin-protein ligase UHRF1 that is encoded in the genome of human.


histone H3 ubiquitin ligase activity

description: Catalysis of the transfer of ubiquitin to a histone H3 substrate.


name: GPHA2_HUMAN Glycoprotein hormone alpha-2 (sprot)

description: A glycoprotein hormone alpha-2 that is encoded in the genome of human.


name: INSM2_HUMAN Insulinoma-associated protein 2 (sprot)

description: An insulinoma-associated protein 2 that is encoded in the genome of human.


name: PCDBI_HUMAN Putative protocadherin beta-18 (sprot)


NIBA2_HUMAN Protein Niban 2 (sprot)

A protein Niban 2 that is encoded in the genome of human.


name: YMEL1_HUMAN ATP-dependent zinc metalloprotease YME1L1 (sprot)

description: An ATP-dependent zinc metalloprotease YME1L1 that is encoded in the genome of human.


name: RMD3_HUMAN Regulator of microtubule dynamics protein 3 (sprot)

description: A regulator of microtubule dynamics protein 3 that is encoded in the genome of human.


name: CSF3R_HUMAN Granulocyte colony-stimulating factor receptor (sprot)

description: A granulocyte colony-stimulating factor receptor that is encoded in the genome of human.


name: granulocyte colony-stimulating factor binding

description: Binding to granulocyte colony-stimulating factor, G-CSF.


name: HBEGF_HUMAN Proheparin-binding EGF-like growth factor (sprot)

description: A proheparin-binding EGF-like growth factor that is encoded in the genome of human.


name: negative regulation of elastin biosynthetic process

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of elastin.


name: HTF4_HUMAN Transcription factor 12 (sprot)

description: A transcription factor 12 that is encoded in the genome of human.


name: response to gonadotropin-releasing hormone

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gonadotropin-releasing hormone stimulus. Gonadotropin-releasing hormone (GnRH) is a peptide hormone responsible for the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the anterior pituitary. GnRH is synthesized and released by the hypothalamus.


MUC4_HUMAN Mucin-4 (sprot)

A mucin-4 that is encoded in the genome of human.


name: AMELX_HUMAN Amelogenin, X isoform (sprot)

description: An amelogenin, X isoform that is encoded in the genome of human.


name: AMELY_HUMAN Amelogenin, Y isoform (sprot)

description: An amelogenin, Y isoform that is encoded in the genome of human.


name: SCN2A_HUMAN Sodium channel protein type 2 subunit alpha (sprot)

description: A sodium channel protein type 2 subunit alpha that is encoded in the genome of human.


name: DCE1_HUMAN Glutamate decarboxylase 1 (sprot)

description: A glutamate decarboxylase 1 that is encoded in the genome of human.


glutamate decarboxylase activity

description: Catalysis of the reaction: L-glutamate = 4-aminobutanoate + CO2.


glutamate decarboxylation to succinate

description: The chemical reactions and pathways resulting in the formation of succinate from glutamate. Also known as GABA (gamma-aminobutyrate) shunt since it channels glutamate into the TCA cycle bypassing two steps of that cycle. There are three enzymes involved in the GABA shunt: glutamate decarboxylase (GAD), GABA aminotransferase (GABA-TA), and succinate semialdehyde dehydrogenase (SSADH). These three enzymes acting in concert to convert glutamate into succinate. The GABA shunt is predominantly associated with neurotransmission in the mammalian brain. It is also present in nonneuronal cells, in plants, in unicellular eukaryotes, and in prokaryotes.


name: MYCBP_HUMAN c-Myc-binding protein (sprot)

description: A c-Myc-binding protein that is encoded in the genome of human.


CYH2_HUMAN Cytohesin-2 (sprot)

A cytohesin-2 that is encoded in the genome of human.


name: ACOX2_HUMAN Peroxisomal acyl-coenzyme A oxidase 2 (sprot)

description: A peroxisomal acyl-coenzyme A oxidase 2 that is encoded in the genome of human.


description: Catalysis of the reaction: (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyl-CoA + H2O + acceptor = (24R,25R)-3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestan-26-oyl-CoA + reduced acceptor.


name: TBCB_HUMAN Tubulin-folding cofactor B (sprot)

description: A tubulin-folding cofactor B that is encoded in the genome of human.


name: NELL2_HUMAN Protein kinase C-binding protein NELL2 (sprot)

description: A protein kinase C-binding protein NELL2 that is encoded in the genome of human.


name: PSB7_HUMAN Proteasome subunit beta type-7 (sprot)

description: A proteasome subunit beta type-7 that is encoded in the genome of human.


name: VATO_HUMAN V-type proton ATPase 21 kDa proteolipid subunit c'' (sprot)

description: A V-type proton ATPase 21 kDa proteolipid subunit c'' that is encoded in the genome of human.


CNN2_HUMAN Calponin-2 (sprot)

A calponin-2 that is encoded in the genome of human.


name: regulation of mononuclear cell proliferation

description: Any process that modulates the frequency, rate or extent of mononuclear cell proliferation.


name: CD006_HUMAN Uncharacterized protein encoded by LINC01587 (sprot)

description: A protein that is a translation product of the LINC01587 gene in human.


name: SEC62_HUMAN Translocation protein SEC62 (sprot)

description: A translocation protein SEC62 that is encoded in the genome of human.


name: GML_HUMAN Glycosyl-phosphatidylinositol-anchored molecule-like protein (sprot)

description: A glycosyl-phosphatidylinositol-anchored molecule-like protein that is encoded in the genome of human.


name: PCY2_HUMAN Ethanolamine-phosphate cytidylyltransferase (sprot)

description: An ethanolamine-phosphate cytidylyltransferase that is encoded in the genome of human.


description: Catalysis of the reaction: CTP + ethanolamine phosphate = diphosphate + CDP-ethanolamine.


name: PHX2B_HUMAN Paired mesoderm homeobox protein 2B (sprot)

description: A paired mesoderm homeobox protein 2B that is encoded in the genome of human.


name: medullary reticular formation development

description: The process whose specific outcome is the progression of the medullary reticular formation over time, from its formation to the mature structure. The medullary reticular formation is a series of brain nuclei located in the medulla oblongata.


name: parasympathetic nervous system development

description: The process whose specific outcome is the progression of the parasympathetic nervous system over time, from its formation to the mature structure. The parasympathetic nervous system is one of the two divisions of the vertebrate autonomic nervous system. Parasympathetic nerves emerge cranially as pre ganglionic fibers from oculomotor, facial, glossopharyngeal and vagus and from the sacral region of the spinal cord. Most neurons are cholinergic and responses are mediated by muscarinic receptors. The parasympathetic system innervates, for example: salivary glands, thoracic and abdominal viscera, bladder and genitalia.


name: efferent axon development in a lateral line nerve

description: The process whose specific outcome is the progression of an efferent axon in a lateral line nerve over time from its formation to the mature structure. This process includes axonogenesis and pathfinding of the efferent axons in any lateral line nerve.


name: retrotrapezoid nucleus neuron differentiation

description: The process in which a relatively unspecialized cell acquires specialized features of a neuron whose cell body resides in the retrotrapezoid nucleus.


cellular response to carbon dioxide

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbon dioxide (CO2) stimulus.


name: K1C12_HUMAN Keratin, type I cytoskeletal 12 (sprot)

description: A keratin, type I cytoskeletal 12 that is encoded in the genome of human.


name: NP1L3_HUMAN Nucleosome assembly protein 1-like 3 (sprot)

description: A nucleosome assembly protein 1-like 3 that is encoded in the genome of human.


name: CDC5L_HUMAN Cell division cycle 5-like protein (sprot)

description: A cell division cycle 5-like protein that is encoded in the genome of human.


name: PSMD1_HUMAN 26S proteasome non-ATPase regulatory subunit 1 (sprot)

description: A 26S proteasome non-ATPase regulatory subunit 1 that is encoded in the genome of human.


name: NPY6R_HUMAN Putative neuropeptide Y receptor type 6 (sprot)


name: NOTC4_HUMAN Neurogenic locus notch homolog protein 4 (sprot)

description: A neurogenic locus notch homolog protein 4 that is encoded in the genome of human.


CD180_HUMAN CD180 antigen (sprot)

A CD180 molecule that is encoded in the genome of human.


name: STAC_HUMAN SH3 and cysteine-rich domain-containing protein (sprot)

description: An SH3 and cysteine-rich domain-containing protein that is encoded in the genome of human.


name: SDF2_HUMAN Stromal cell-derived factor 2 (sprot)

description: A stromal cell-derived factor 2 that is encoded in the genome of human.


PFD5_HUMAN Prefoldin subunit 5 (sprot)

A prefoldin subunit 5 that is encoded in the genome of human.


name: PAFA2_HUMAN Platelet-activating factor acetylhydrolase 2, cytoplasmic (sprot)

description: A platelet-activating factor acetylhydrolase 2, cytoplasmic that is encoded in the genome of human.


OXDD_HUMAN D-aspartate oxidase (sprot)

A D-aspartate oxidase that is encoded in the genome of human.


D-aspartate oxidase activity

description: Catalysis of the reaction: D-aspartate + H2O + O2 = oxaloacetate + NH3 + hydrogen peroxide.


D-glutamate oxidase activity

description: Catalysis of the reaction: D-glutamate + H2O + O2 = 2-oxoglutarate + NH3 + H2O2.


regulation of cell communication

description: Any process that modulates the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.


name: AGAP2_HUMAN Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2 (sprot)

description: An Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2 that is encoded in the genome of human.


name: RING2_HUMAN E3 ubiquitin-protein ligase RING2 (sprot)

description: An E3 ubiquitin-protein ligase RING2 that is encoded in the genome of human.


name: PARK7_HUMAN Parkinson disease protein 7 (sprot)

description: A parkinson disease protein 7 that is encoded in the genome of human.


protein deglycase activity

description: Catalysis of the removal of a sugar or dicarbonyl from a glycated L-arginine, L-lysine or L-cysteine residue within proteins that have been attacked and modified by glyoxal or 2-oxopropanal.


name: protein deglycation, methylglyoxal removal

description: The removal of methylglyoxal from a glycated protein, to form lactate and a deglycated protein.


name: tyrosine 3-monooxygenase activator activity

description: Binds to and increases the activity of tyrosine 3-monooxygenase (tyrosine hydroxylase).


L-dopa decarboxylase activator activity

description: Interacts with and increases L-dopa decarboxylase activity.


name: glyoxalase (glycolic acid-forming) activity

description: Catalysis of the reaction: glyoxal + H2O = glycolic acid. Catalysis occurs in the absence of a cofactor.


cellular response to glyoxal

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glyoxal stimulus.


peptidyl-cysteine deglycation

description: The removal of a sugar or dicarbonyl from a cysteine residue of a glycated protein.


peptidyl-arginine deglycation

description: The removal of a sugar or dicarbonyl from an arginine residue of a glycated protein.


peptidyl-lysine deglycation

description: The removal of a sugar or dicarbonyl from a lysine residue of a glycated protein.


protein deglycation, glyoxal removal

description: The removal of glyoxal from a glycated protein, to form glycolate and a deglycated protein.


glycolate biosynthetic process

description: The chemical reactions and pathways resulting in the formation of glycolate, the anion of hydroxyethanoic acid (glycolic acid).


detoxification of mercury ion

description: Any process that reduce or remove the toxicity of mercuric ion. These include transport of mercury away from sensitive areas and to compartments or complexes whose purpose is sequestration of mercury ion and/or reduction of mercury ion (Hg[II]) to metallic mercury (Hg[0]).


detoxification of hydrogen peroxide

description: Any process that reduces or removes the toxicity of hydrogen peroxide. These include transport of hydrogen peroxide away from sensitive areas and to compartments or complexes whose purpose is sequestration.


name: methylglyoxal catabolic process to lactate

description: The chemical reactions and pathways resulting in the breakdown of methylglyoxal, CH3-CO-CHO, into lactate.


guanine deglycation

description: The removal of a sugar or dicarbonyl from a glycated guanine.


name: guanine deglycation, methylglyoxal removal

description: The removal of methylglyoxal from a glycated guanine, to form lactate and a deglycated guanine.


guanine deglycation, glyoxal removal

description: The removal of glyoxal from a glycated guanine, to form glycolate and a deglycated guanine.


name: cellular detoxification of methylglyoxal

description: Any process carried out at the cellular level that reduces or removes the toxicity of methylglyoxal. These may include chemical modification or transport of methylglyoxal away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance.


name: positive regulation of superoxide dismutase activity

description: Any process that activates or increases the frequency, rate or extent of superoxide dismutase activity.


name: regulation of supramolecular fiber organization

description: Any process that modulates the frequency, rate or extent of supramolecular fiber organization.


name: positive regulation of mitochondrial electron transport, NADH to ubiquinone

description: Any process that activates or increases the frequency, rate or extent of mitochondrial electron transport, NADH to ubiquinone.


name: negative regulation of death-inducing signaling complex assembly

description: Any process that stops, prevents or reduces the frequency, rate or extent of death-inducing signaling complex assembly.


name: negative regulation of TRAIL-activated apoptotic signaling pathway

description: Any process that stops, prevents or reduces the frequency, rate or extent of TRAIL-activated apoptotic signaling pathway.


name: positive regulation of pyrroline-5-carboxylate reductase activity

description: Any process that activates or increases the frequency, rate or extent of pyrroline-5-carboxylate reductase activity.


name: positive regulation of tyrosine 3-monooxygenase activity

description: Any process that activates or increases the frequency, rate or extent of tyrosine 3-monooxygenase activity.


glyoxal metabolic process

description: The chemical reactions and pathways involving glyoxal.


glyoxal catabolic process

description: The chemical reactions and pathways resulting in the breakdown of glyoxal.


name: positive regulation of L-dopa biosynthetic process

description: Any process that activates or increases the frequency, rate or extent of L-dopa biosynthetic process.


name: positive regulation of L-dopa decarboxylase activity

description: Any process that activates or increases the frequency, rate or extent of L-dopa decarboxylase activity.


name: negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway

description: Any process that stops, prevents or reduces the frequency, rate or extent of a hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway.


name: S1PR3_HUMAN Sphingosine 1-phosphate receptor 3 (sprot)

description: A sphingosine 1-phosphate receptor 3 that is encoded in the genome of human.


GA2L1_HUMAN GAS2-like protein 1 (sprot)

A GAS2-like protein 1 that is encoded in the genome of human.


name: EYA1_HUMAN Eyes absent homolog 1 (sprot)

description: An eyes absent homolog 1 that is encoded in the genome of human.


otic vesicle morphogenesis

description: The process in which the anatomical structures of the otic vesicle are generated and organized. The otic vesicle is a transient embryonic structure formed during development of the vertebrate inner ear.


name: EYA3_HUMAN Eyes absent homolog 3 (sprot)

description: An eyes absent homolog 3 that is encoded in the genome of human.


name: FMO2_HUMAN Flavin-containing monooxygenase 2 (sprot)

description: A flavin-containing monooxygenase 2 that is encoded in the genome of human.


NEUR1_HUMAN Sialidase-1 (sprot)

A sialidase-1 that is encoded in the genome of human.


alpha-sialidase activity

description: Catalysis of the hydrolysis of alpha-glycosidic linkages in oligo- or poly(sialic) acids.


SORT_HUMAN Sortilin (sprot)

A sortilin that is encoded in the genome of human.


name: neurotensin receptor activity, non-G protein-coupled

description: Combining with neurotensin, a neuropeptide active in the central and peripheral nervous system in mammals, and transmitting the signal from one side of the membrane to the other by a mechanism independent of coupling to G proteins.


name: H4G_HUMAN Histone H4-like protein type G (sprot)

description: A histone H4-like protein type G that is encoded in the genome of human.


name: GPER1_HUMAN G-protein coupled estrogen receptor 1 (sprot)

description: A G-protein coupled estrogen receptor 1 that is encoded in the genome of human.


name: G protein-coupled estrogen receptor activity

description: Combining with estrogen and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.


name: nuclear fragmentation involved in apoptotic nuclear change

description: The breakdown of the nucleus into small membrane-bounded compartments, or blebs, each of which contain compacted DNA.


name: positive regulation of cardiac vascular smooth muscle cell differentiation

description: Any process that activates or increases the frequency, rate or extent of cardiac vascular smooth muscle cell differentiation.


name: VAT1_HUMAN Synaptic vesicle membrane protein VAT-1 homolog (sprot)

description: A synaptic vesicle membrane protein VAT-1 that is encoded in the genome of human.


LGMN_HUMAN Legumain (sprot)

A legumain that is encoded in the genome of human.


PLIN2_HUMAN Perilipin-2 (sprot)

A perilipin-2 that is encoded in the genome of human.


name: MMP19_HUMAN Matrix metalloproteinase-19 (sprot)

description: A matrix metalloproteinase-19 that is encoded in the genome of human.


name: DNJC2_HUMAN DnaJ homolog subfamily C member 2 (sprot)

description: A DnaJ homolog subfamily C member 2 that is encoded in the genome of human.


name: MPH6_HUMAN M-phase phosphoprotein 6 (sprot)

description: An M-phase phosphoprotein 6 that is encoded in the genome of human.


name: MPP8_HUMAN M-phase phosphoprotein 8 (sprot)

description: An M-phase phosphoprotein 8 that is encoded in the genome of human.


name: MPP9_HUMAN M-phase phosphoprotein 9 (sprot)

description: An M-phase phosphoprotein 9 that is encoded in the genome of human.


name: MTEF1_HUMAN Transcription termination factor 1, mitochondrial (sprot)

description: A transcription termination factor 1, mitochondrial that is encoded in the genome of human.


name: termination of mitochondrial transcription

description: A transcription termination process that completes the production of a primary mitochondrial transcript.


name: M3K14_HUMAN Mitogen-activated protein kinase kinase kinase 14 (sprot)

description: A mitogen-activated protein kinase kinase kinase 14 that is encoded in the genome of human.


name: NUP88_HUMAN Nuclear pore complex protein Nup88 (sprot)

description: A nuclear pore complex protein Nup88 that is encoded in the genome of human.


PKP4_HUMAN Plakophilin-4 (sprot)

A plakophilin-4 that is encoded in the genome of human.


name: PI3R4_HUMAN Phosphoinositide 3-kinase regulatory subunit 4 (sprot)

description: A phosphoinositide 3-kinase regulatory subunit 4 that is encoded in the genome of human.


P2RX4_HUMAN P2X purinoceptor 4 (sprot)

A P2X purinoceptor 4 that is encoded in the genome of human.


P2RX7_HUMAN P2X purinoceptor 7 (sprot)

A P2X purinoceptor 7 that is encoded in the genome of human.


NAD transport

description: The directed movement of nicotinamide adenine dinucleotide into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore; transport may be of either the oxidized form, NAD, or the reduced form, NADH.


positive regulation of bleb assembly

description: Any process that activates or increases the frequency, rate or extent of bleb assembly.


NEUS_HUMAN Neuroserpin (sprot)

A neuroserpin that is encoded in the genome of human.


name: POP1_HUMAN Ribonucleases P/MRP protein subunit POP1 (sprot)

description: A ribonucleases P/MRP protein subunit POP1 that is encoded in the genome of human.


name: T22D3_HUMAN TSC22 domain family protein 3 (sprot)

description: A TSC22 domain family protein 3 that is encoded in the genome of human.


name: RIT2_HUMAN GTP-binding protein Rit2 (sprot)

description: A GTP-binding protein Rit2 that is encoded in the genome of human.


FEV_HUMAN Protein FEV (sprot)

A protein FEV that is encoded in the genome of human.


name: MNT_HUMAN Max-binding protein MNT (sprot)

description: A Max-binding protein MNT that is encoded in the genome of human.


S10AD_HUMAN Protein S100-A13 (sprot)

A protein S100-A13 that is encoded in the genome of human.


SCAFB_HUMAN Protein SCAF11 (sprot)

A protein SCAF11 that is encoded in the genome of human.


name: ZBT18_HUMAN Zinc finger and BTB domain-containing protein 18 (sprot)

description: A zinc finger and BTB domain-containing protein 18 that is encoded in the genome of human.


name: TBX5_HUMAN T-box transcription factor TBX5 (sprot)

description: A T-box transcription factor TBX5 that is encoded in the genome of human.


name: positive regulation of cardiac conduction

description: Any process that activates or increases the frequency, rate or extent of cardiac conduction.


name: cell migration involved in coronary vasculogenesis

description: The orderly movement of a cell from one site to another that will contribute to the differentiation of an endothelial cell that will form the blood vessels of the heart.


name: TEAD3_HUMAN Transcriptional enhancer factor TEF-5 (sprot)

description: A transcriptional enhancer factor TEF-5 that is encoded in the genome of human.


name: TI17A_HUMAN Mitochondrial import inner membrane translocase subunit Tim17-A (sprot)

description: A mitochondrial import inner membrane translocase subunit Tim17-A that is encoded in the genome of human.


name: TSNAX_HUMAN Translin-associated protein X (sprot)

description: A translin-associated protein X that is encoded in the genome of human.


name: TRGV9_HUMAN T cell receptor gamma variable 9 (sprot)

description: A protein that is a translation product of the TRGV9 gene in human.


name: ELF4_HUMAN ETS-related transcription factor Elf-4 (sprot)

description: An ETS-related transcription factor Elf-4 that is encoded in the genome of human.


NECD_HUMAN Necdin (sprot)

A necdin that is encoded in the genome of human.


name: SPS2_HUMAN Selenide, water dikinase 2 (sprot)

description: A selenide, water dikinase 2 that is encoded in the genome of human.


selenide, water dikinase activity

description: Catalysis of the reaction: ATP + H2O + hydrogen selenide = AMP + 3 H+ + phosphate + selenophosphorate.


selenium compound metabolic process

description: The chemical reactions and pathways involving compounds that contain selenium, such as selenocysteine.


selenocysteine metabolic process

description: The chemical reactions and pathways involving selenocysteine, an essential component of glutathione peroxidase and some other proteins.


selenocysteine biosynthetic process

description: The chemical reactions and pathways resulting in the formation of selenocysteine, an essential component of glutathione peroxidase and some other proteins.


name: KLF6_HUMAN Krueppel-like factor 6 (sprot)

description: A krueppel-like factor 6 that is encoded in the genome of human.


name: EIF3C_HUMAN Eukaryotic translation initiation factor 3 subunit C (sprot)

description: A protein that is a translation product of the EIF3C gene in human.


name: TTC1_HUMAN Tetratricopeptide repeat protein 1 (sprot)

description: A tetratricopeptide repeat protein 1 that is encoded in the genome of human.


name: DNJC7_HUMAN DnaJ homolog subfamily C member 7 (sprot)

description: A DnaJ homolog subfamily C member 7 that is encoded in the genome of human.


name: CCL13_HUMAN C-C motif chemokine 13 (sprot)

description: A C-C motif chemokine 13 that is encoded in the genome of human.


name: CDCA3_HUMAN Cell division cycle-associated protein 3 (sprot)

description: A cell division cycle-associated protein 3 that is encoded in the genome of human.


name: SPSB2_HUMAN SPRY domain-containing SOCS box protein 2 (sprot)

description: A SPRY domain-containing SOCS box protein 2 that is encoded in the genome of human.


C10_HUMAN Protein C10 (sprot)

A protein C10 that is encoded in the genome of human.


PHB2_HUMAN Prohibitin-2 (sprot)

A prohibitin-2 that is encoded in the genome of human.


name: regulation of cytochrome-c oxidase activity

description: Any process that modulates the frequency, rate or extent of cytochrome-c oxidase activity.


name: S38A3_HUMAN Sodium-coupled neutral amino acid transporter 3 (sprot)

description: A sodium-coupled neutral amino acid transporter 3 that is encoded in the genome of human.


name: L-asparagine, sodium:proton antiporter activity

description: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(in) + L-asparagine(out) + Na+(out) = H+(out) + L-asparagine(in) + Na+(in).


name: L-histidine, sodium:proton antiporter activity

description: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(in) + L-histidine(out) + Na+(out) = H+(out) + L-histidine(in) + Na+(in).


histidine transport

description: The directed movement of histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


name: L-asparagine import across plasma membrane

description: The directed movement of L-asparagine from outside of a cell, across the plasma membrane and into the cytosol.


name: positive regulation of glutamine transport

description: Any process that activates or increases the frequency, rate or extent of glutamine transport.


name: CDX2_HUMAN Homeobox protein CDX-2 (sprot)

description: A homeobox protein CDX-2 that is encoded in the genome of human.


name: CSN8_HUMAN COP9 signalosome complex subunit 8 (sprot)

description: A COP9 signalosome complex subunit 8 that is encoded in the genome of human.


name: PRP18_HUMAN Pre-mRNA-splicing factor 18 (sprot)

description: A pre-mRNA-splicing factor 18 that is encoded in the genome of human.


name: RAD9A_HUMAN Cell cycle checkpoint control protein RAD9A (sprot)

description: A cell cycle checkpoint control protein RAD9A that is encoded in the genome of human.


name: PMYT1_HUMAN Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (sprot)

description: A membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase that is encoded in the genome of human.


name: C560_HUMAN Succinate dehydrogenase cytochrome b560 subunit, mitochondrial (sprot)

description: A succinate dehydrogenase cytochrome b560 subunit, mitochondrial that is encoded in the genome of human.


EPYC_HUMAN Epiphycan (sprot)

An epiphycan that is encoded in the genome of human.


name: OSMR_HUMAN Oncostatin-M-specific receptor subunit beta (sprot)

description: An oncostatin-M-specific receptor subunit beta that is encoded in the genome of human.


name: CHP1_HUMAN Calcineurin B homologous protein 1 (sprot)

description: A calcineurin B homologous protein 1 that is encoded in the genome of human.


membrane docking

description: The initial attachment of a membrane or protein to a target membrane. Docking requires only that the proteins come close enough to interact and adhere.


name: KIF2C_HUMAN Kinesin-like protein KIF2C (sprot)

description: A kinesin-like protein KIF2C that is encoded in the genome of human.


name: I12R2_HUMAN Interleukin-12 receptor subunit beta-2 (sprot)

description: An interleukin-12 receptor subunit beta-2 that is encoded in the genome of human.


name: CGRE1_HUMAN Cell growth regulator with EF hand domain protein 1 (sprot)

description: A cell growth regulator with EF hand domain protein 1 that is encoded in the genome of human.


name: CGRF1_HUMAN Cell growth regulator with RING finger domain protein 1 (sprot)

description: A cell growth regulator with RING finger domain protein 1 that is encoded in the genome of human.


name: ZN184_HUMAN Zinc finger protein 184 (sprot)

description: A zinc finger protein 184 that is encoded in the genome of human.


name: LPAR4_HUMAN Lysophosphatidic acid receptor 4 (sprot)

description: A lysophosphatidic acid receptor 4 that is encoded in the genome of human.


name: GPR20_HUMAN G-protein coupled receptor 20 (sprot)

description: A G-protein coupled receptor 20 that is encoded in the genome of human.


name: GPR21_HUMAN Probable G-protein coupled receptor 21 (sprot)

description: A probable G-protein coupled receptor 21 that is encoded in the genome of human.


name: GPR22_HUMAN G-protein coupled receptor 22 (sprot)

description: A G-protein coupled receptor 22 that is encoded in the genome of human.


name: M3K5_HUMAN Mitogen-activated protein kinase kinase kinase 5 (sprot)

description: A mitogen-activated protein kinase kinase kinase 5 that is encoded in the genome of human.


name: neuron intrinsic apoptotic signaling pathway in response to oxidative stress

category: biolink:Pathway biolink:OntologyClass biolink:BiologicalProcess biolink:Occurrent biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: The series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a neuron. The pathway is induced in response to oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, and ends when the execution phase of apoptosis is triggered.


name: GFI1_HUMAN Zinc finger protein Gfi-1 (sprot)

description: A zinc finger protein Gfi-1 that is encoded in the genome of human.


MGLL_HUMAN Monoglyceride lipase (sprot)

A monoglyceride lipase that is encoded in the genome of human.


name: regulation of endocannabinoid signaling pathway

description: Any process that modulates the frequency, rate or extent of endocannabinoid signaling pathway.


name: MEIS3_HUMAN Homeobox protein Meis3 (sprot)

description: A homeobox protein Meis3 that is encoded in the genome of human.


name: FEZ1_HUMAN Fasciculation and elongation protein zeta-1 (sprot)

description: A fasciculation and elongation protein zeta-1 that is encoded in the genome of human.


name: positive regulation of anterograde axonal transport of mitochondrion

description: Any process that activates or increasesthe frequency, rate or extent of the directed movement of mitochondria along microtubules in axons away from the cell body and towards the presynapse.


name: PITX2_HUMAN Pituitary homeobox 2 (sprot)

description: A pituitary homeobox 2 that is encoded in the genome of human.


name: prolactin secreting cell differentiation

description: The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a prolactin secreting cell. A prolactin secreting cell is an acidophilic cell of the anterior pituitary that produces prolactin.


name: LYST_HUMAN Lysosomal-trafficking regulator (sprot)

description: A lysosomal-trafficking regulator that is encoded in the genome of human.


ATX2_HUMAN Ataxin-2 (sprot)

An ataxin-2 that is encoded in the genome of human.


DOK1_HUMAN Docking protein 1 (sprot)

A docking protein 1 that is encoded in the genome of human.


name: MCHR1_HUMAN Melanin-concentrating hormone receptor 1 (sprot)

description: A melanin-concentrating hormone receptor 1 that is encoded in the genome of human.


name: melanin-concentrating hormone receptor activity

description: Combining with the cyclic peptide hormone melanin-concentrating hormone to initiate a change in cell activity.


name: KI2L4_HUMAN Killer cell immunoglobulin-like receptor 2DL4 (sprot)

description: A killer cell immunoglobulin-like receptor 2DL4 that is encoded in the genome of human.


METH_HUMAN Methionine synthase (sprot)

A methionine synthase that is encoded in the genome of human.


methionine synthase activity

description: Catalysis of the reaction: (6S)-5-methyl-5,6,7,8-tetrahydrofolate + L-homocysteine = (6S)-5,6,7,8-tetrahydrofolate + L-methionine.


name: CTIP_HUMAN DNA endonuclease RBBP8 (sprot)

description: A DNA endonuclease RBBP8 that is encoded in the genome of human.


name: KCJ15_HUMAN ATP-sensitive inward rectifier potassium channel 15 (sprot)

description: An ATP-sensitive inward rectifier potassium channel 15 that is encoded in the genome of human.


name: HCD2_HUMAN 3-hydroxyacyl-CoA dehydrogenase type-2 (sprot)

description: A 3-hydroxyacyl-CoA dehydrogenase type-2 that is encoded in the genome of human.


cholate 7-alpha-dehydrogenase activity

description: Catalysis of the reaction: cholate + NAD+ = 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanate + H+ + NADH.


name: 17-beta-hydroxysteroid dehydrogenase (NAD+) activity

description: Catalysis of the reaction: a 17-beta-hydroxysteroid + NAD+ = a 17-oxosteroid + NADH + H+.


description: Catalysis of the reaction: NAD+ + 2-methyl-3-hydroxybutyryl-CoA = NADH + H+ + 2-methylaceto-acetyl-CoA.


name: chenodeoxycholate 7-alpha-dehydrogenase (NAD+) activity

description: Catalysis of the reaction: chenodeoxycholate + NAD+ = 7-oxolithocholate + H+ + NADH.


name: isoursodeoxycholate 7-beta-dehydrogenase (NAD+) activity

description: Catalysis of the reaction: 3beta,7beta-dihydroxy-5beta-cholan-24-oate + NAD+ = 3beta-hydroxy-7-oxo-5beta-cholan-24-oate + H+ + NADH.


name: ursodeoxycholate 7-beta-dehydrogenase (NAD+) activity

description: Catalysis of the reaction: NAD+ + ursodeoxycholate = 7-oxolithocholate + H+ + NADH.


brexanolone metabolic process

description: The chemical reactions and pathways by which living organisms transform brexanolone.


name: COCA1_HUMAN Collagen alpha-1(XII) chain (sprot)

description: A collagen alpha-1(XII) chain that is encoded in the genome of human.


collagen type XII trimer

category: biolink:CellularComponent biolink:AnatomicalEntity biolink:PhysicalEssence biolink:OrganismalEntity biolink:SubjectOfInvestigation biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: A collagen homotrimer of alpha1(XII) chains; type XII collagen triple helices may link sheet-forming or fibrillar collagens to other structures.


name: SMAD5_HUMAN Mothers against decapentaplegic homolog 5 (sprot)

description: A smad5 that is encoded in the genome of human.


SEPT5_HUMAN Septin-5 (sprot)

A septin-5 that is encoded in the genome of human.


name: SGMR1_HUMAN Sigma non-opioid intracellular receptor 1 (sprot)

description: A sigma non-opioid intracellular receptor 1 that is encoded in the genome of human.


name: ZNT3_HUMAN Probable proton-coupled zinc antiporter SLC30A3 (sprot)

description: A probable proton-coupled zinc antiporter SLC30A3 that is encoded in the genome of human.


positive regulation of transport

description: Any process that activates or increases the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


name: TIMP4_HUMAN Metalloproteinase inhibitor 4 (sprot)

description: A metalloproteinase inhibitor 4 that is encoded in the genome of human.


name: BARD1_HUMAN BRCA1-associated RING domain protein 1 (sprot)

description: A BRCA1-associated RING domain protein 1 that is encoded in the genome of human.


name: negative regulation of mRNA 3'-end processing

description: Any process that stops, prevents, or reduces the frequency, rate or extent of mRNA 3'-end processing.


name: ROAA_HUMAN Heterogeneous nuclear ribonucleoprotein A/B (sprot)

description: A heterogeneous nuclear ribonucleoprotein A/B that is encoded in the genome of human.


name: CCL19_HUMAN C-C motif chemokine 19 (sprot)

description: A C-C motif chemokine 19 that is encoded in the genome of human.


name: positive regulation of dendritic cell dendrite assembly

description: Any process that activates or increases the frequency, rate or extent of dendritic cell dendrite assembly.


name: LITAF_HUMAN Lipopolysaccharide-induced tumor necrosis factor-alpha factor (sprot)

description: A lipopolysaccharide-induced tumor necrosis factor-alpha factor that is encoded in the genome of human.


name: regulation of macrophage cytokine production

description: Any process that modulates the rate, frequency or extent of macrophage cytokine production. Macrophage cytokine production is the appearance of a chemokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


name: cytoplasmic side of late endosome membrane

description: The side (leaflet) of the late endosome membrane that faces the cytoplasm.


name: NP1L4_HUMAN Nucleosome assembly protein 1-like 4 (sprot)

description: A nucleosome assembly protein 1-like 4 that is encoded in the genome of human.


name: MGST2_HUMAN Microsomal glutathione S-transferase 2 (sprot)

description: A microsomal glutathione S-transferase 2 that is encoded in the genome of human.


name: CDC6_HUMAN Cell division control protein 6 homolog (sprot)

description: A cell division control protein 6 that is encoded in the genome of human.


name: NPAS1_HUMAN Neuronal PAS domain-containing protein 1 (sprot)

description: A neuronal PAS domain-containing protein 1 that is encoded in the genome of human.


name: NPAS2_HUMAN Neuronal PAS domain-containing protein 2 (sprot)

description: A neuronal PAS domain-containing protein 2 that is encoded in the genome of human.


name: SNAG_HUMAN Gamma-soluble NSF attachment protein (sprot)

description: A gamma-soluble NSF attachment protein that is encoded in the genome of human.


NRTN_HUMAN Neurturin (sprot)

A neurturin that is encoded in the genome of human.


name: MDFI_HUMAN MyoD family inhibitor (sprot)

description: A MyoD family inhibitor that is encoded in the genome of human.


name: PI51A_HUMAN Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha (sprot)

description: A phosphatidylinositol 4-phosphate 5-kinase type-1 alpha that is encoded in the genome of human.


name: THIOM_HUMAN Thioredoxin, mitochondrial (sprot)

description: A thioredoxin, mitochondrial that is encoded in the genome of human.


name: peptide-methionine (S)-S-oxide reductase activity

description: Catalysis of the reactions: peptide-L-methionine + thioredoxin disulfide + H2O = peptide-L-methionine (S)-S-oxide + thioredoxin, and L-methionine + thioredoxin disulfide + H2O = L-methionine (S)-S-oxide + thioredoxin. Can act on oxidized methionine in peptide linkage with specificity for the S enantiomer. Thioredoxin disulfide is the oxidized form of thioredoxin.


name: ABCA3_HUMAN Phospholipid-transporting ATPase ABCA3 (sprot)

description: A phospholipid-transporting ATPase ABCA3 that is encoded in the genome of human.


name: positive regulation of protein homooligomerization

description: Any process that activates or increases the frequency, rate or extent of protein homooligomerization.


lamellar body membrane

description: The lipid bilayer surrounding a lamellar body. A lamellar body is a membrane-bounded organelle, specialized for the storage and secretion of various substances (surfactant phospholipids, glycoproteins and acid phosphates) which are arranged in the form of tightly packed, concentric, membrane sheets or lamellae. Has some similar properties to, but is distinct from, a lysosome.


name: M3K3_HUMAN Mitogen-activated protein kinase kinase kinase 3 (sprot)

description: A mitogen-activated protein kinase kinase kinase 3 that is encoded in the genome of human.


name: ATP5S_HUMAN ATP synthase subunit s, mitochondrial (sprot)

description: An ATP synthase subunit s, mitochondrial that is encoded in the genome of human.


name: APBA2_HUMAN Amyloid-beta A4 precursor protein-binding family A member 2 (sprot)

description: An amyloid-beta A4 precursor protein-binding family A member 2 that is encoded in the genome of human.


NOE1_HUMAN Noelin (sprot)

A noelin that is encoded in the genome of human.


name: CML1_HUMAN Chemerin-like receptor 1 (sprot)

description: A chemokine receptor-like protein CMKLR1 that is encoded in the genome of human.


name: GPA33_HUMAN Cell surface A33 antigen (sprot)

description: A cell surface A33 antigen that is encoded in the genome of human.


name: MIPEP_HUMAN Mitochondrial intermediate peptidase (sprot)

description: A mitochondrial intermediate peptidase that is encoded in the genome of human.


name: ACON_HUMAN Aconitate hydratase, mitochondrial (sprot)

description: An aconitate hydratase, mitochondrial that is encoded in the genome of human.


name: NKX31_HUMAN Homeobox protein Nkx-3.1 (sprot)

description: A homeobox protein Nkx-3.1 that is encoded in the genome of human.


MADS box domain binding

description: Binding to a MADS box domain, a protein domain that encodes the DNA-binding MADS domain. The MADS domain binds to DNA sequences of high similarity to the motif CC[A/T]6GG termed the CArG-box. MADS-domain proteins are generally transcription factors. The length of the MADS-box is in the range of 168 to 180 base pairs.


name: positive regulation of androgen secretion

description: Any process that activates or increases the frequency, rate or extent of androgen secretion.


name: TM9S2_HUMAN Transmembrane 9 superfamily member 2 (sprot)

description: A transmembrane 9 superfamily member 2 that is encoded in the genome of human.


name: regulation of heparan sulfate proteoglycan biosynthetic process

description: Any process that modulates the rate, frequency or extent of heparan sulfate proteoglycan biosynthesis. Heparan sulfate proteoglycan biosynthetic processes are the chemical reactions and pathways resulting in the formation of the heparan sulfate proteoglycan, a glycosaminoglycan with repeat unit consisting of alternating alpha-(1->4)-linked hexuronic acid and glucosamine residues.


name: COQ7_HUMAN 5-demethoxyubiquinone hydroxylase, mitochondrial (sprot)

description: A ubiquinone biosynthesis protein COQ7 that is encoded in the genome of human.


name: S29A1_HUMAN Equilibrative nucleoside transporter 1 (sprot)

description: An equilibrative nucleoside transporter 1 that is encoded in the genome of human.


name: pyrimidine nucleobase transmembrane transport

description: The process in which pyrimidine is transported across a membrane.


name: PRRX2_HUMAN Paired mesoderm homeobox protein 2 (sprot)

description: A paired mesoderm homeobox protein 2 that is encoded in the genome of human.


name: EPAS1_HUMAN Endothelial PAS domain-containing protein 1 (sprot)

description: An endothelial PAS domain-containing protein 1 that is encoded in the genome of human.


name: TS101_HUMAN Tumor susceptibility gene 101 protein (sprot)

description: A tumor susceptibility gene 101 protein that is encoded in the genome of human.


name: positive regulation of viral budding via host ESCRT complex

description: Any process that activates or increases the frequency, rate or extent of viral budding via host ESCRT complex.


name: positive regulation of ubiquitin-dependent endocytosis

description: Any process that activates or increases the frequency, rate or extent of ubiquitin-dependent endocytosis.


name: GDIR3_HUMAN Rho GDP-dissociation inhibitor 3 (sprot)

description: A Rho GDP-dissociation inhibitor 3 that is encoded in the genome of human.


name: CIB1_HUMAN Calcium and integrin-binding protein 1 (sprot)

description: A calcium and integrin-binding protein 1 that is encoded in the genome of human.


name: calcium-dependent protein kinase inhibitor activity

description: Binds to and stops, prevents or reduces the activity of a calcium-dependent protein kinase.


CPNE1_HUMAN Copine-1 (sprot)

A copine-1 that is encoded in the genome of human.


name: TCPH_HUMAN T-complex protein 1 subunit eta (sprot)

description: A T-complex protein 1 subunit eta that is encoded in the genome of human.


SMO_HUMAN Protein smoothened (sprot)

A protein smoothened that is encoded in the genome of human.


ventral midline determination

description: The regionalization process in which the area where the ventral midline will form is specified.


name: mesenchymal to epithelial transition involved in metanephric renal vesicle formation

description: A transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephric renal vesicle.


regulation of heart morphogenesis

description: Any process that modulates the frequency, rate or extent of heart morphogenesis.


name: MYD88_HUMAN Myeloid differentiation primary response protein MyD88 (sprot)

description: A myeloid differentiation primary response protein MyD88 that is encoded in the genome of human.


Toll binding

description: Binding to a Toll protein, a transmembrane receptor.


TIR domain binding

description: Binding to a Toll-Interleukin receptor (TIR) domain of a protein. The TIR domain is an intracellular 200 residue domain that is found in the Toll protein, the interleukin-1 receptor (IL-1R), and MyD88; it contains three highly-conserved regions, and mediates protein-protein interactions between the Toll-like receptors (TLRs) and signal-transduction components.


name: ATP-dependent histone chaperone activity

description: Binding to and carrying a histone or a histone complex to unload or deposit it as a nucleosome, driven by ATP hydrolysis.


response to molecule of fungal origin

description: Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by molecules of fungal origin such as chito-octamer oligosaccharide.


induced systemic resistance

description: A response to non-pathogenic bacteria that confers broad spectrum systemic resistance to disease that does not depend upon salicylic acid signaling.


toll-like receptor 8 signaling pathway

description: The series of molecular signals initiated by a ligand binding to the endolysosomal toll-like receptor 8.


name: regulation of chemokine (C-X-C motif) ligand 1 production

description: Any process that modulates the frequency, rate or extent of chemokine (C-X-C motif) ligand 1 production.


name: EBP2_HUMAN Probable rRNA-processing protein EBP2 (sprot)

description: A probable rRNA-processing protein EBP2 that is encoded in the genome of human.


name: FOXB1_HUMAN Forkhead box protein B1 (sprot)

description: A forkhead box protein B1 that is encoded in the genome of human.


mammillary body development

description: The progression of the mammillary body over time from its initial formation until its mature state. The mammillary body is a protrusion at the posterior end of the hypothalamus that contains hypothalamic nuclei.


hypothalamus cell migration

description: The directed movement of a cell into the hypothalamus region of the forebrain.


name: mammillothalamic axonal tract development

description: The progression of the mammillothalamic axonal tract, from its formation to the mature structure. The mammillothalamic tract is the collection of axons that connects the two major subdivisions of the diencephalon (hypothalamus and thalamus) and closes the diencephalic circuit.


mammary gland lobule development

description: The progression of the mammary gland lobule over time, from its formation to the mature structure. A mammary gland lobule is a small rounded projection of the mammary gland.


cell migration in diencephalon

description: The orderly movement of a cell that will reside in the diencephalon.


name: ARI3A_HUMAN AT-rich interactive domain-containing protein 3A (sprot)

description: An AT-rich interactive domain-containing protein 3A that is encoded in the genome of human.


SPI2A_HUMAN Spindlin-2A (sprot)

A spindlin-2A that is encoded in the genome of human.


name: HAUS7_HUMAN HAUS augmin-like complex subunit 7 (sprot)

description: A HAUS augmin-like complex subunit 7 that is encoded in the genome of human.


name: ANM1_HUMAN Protein arginine N-methyltransferase 1 (sprot)

description: A protein arginine N-methyltransferase 1 that is encoded in the genome of human.


N-methyltransferase activity

description: Catalysis of the transfer of a methyl group to the nitrogen atom of an acceptor molecule.


GATOR1 complex binding

description: Binding to a GATOR1 complex.


name: H2B1N_HUMAN Histone H2B type 1-N (sprot)

description: A histone H2B type 1-N that is encoded in the genome of human.


name: H2A1J_HUMAN Histone H2A type 1-J (sprot)

description: A histone H2A type 1-J that is encoded in the genome of human.


name: H2B1M_HUMAN Histone H2B type 1-M (sprot)

description: A histone H2B type 1-M that is encoded in the genome of human.


name: H2B1L_HUMAN Histone H2B type 1-L (sprot)

description: A histone H2B type 1-L that is encoded in the genome of human.


name: SC6A7_HUMAN Sodium-dependent proline transporter (sprot)

description: A sodium-dependent proline transporter that is encoded in the genome of human.


CTRC_HUMAN Chymotrypsin-C (sprot)

A chymotrypsin-C that is encoded in the genome of human.


SSX3_HUMAN Protein SSX3 (sprot)

A protein SSX3 that is encoded in the genome of human.


name: GBRG3_HUMAN Gamma-aminobutyric acid receptor subunit gamma-3 (sprot)

description: A gamma-aminobutyric acid receptor subunit gamma-3 that is encoded in the genome of human.


name: ASCL2_HUMAN Achaete-scute homolog 2 (sprot)

description: An achaete-scute homolog 2 that is encoded in the genome of human.


spongiotrophoblast layer development

description: The process in which the spongiotrophoblast layer of the placenta progresses from its formation to its mature state.


chorionic trophoblast cell development

description: The process whose specific outcome is the progression of the chorionic trophoblast over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.


name: SPAG8_HUMAN Sperm-associated antigen 8 (sprot)

description: A sperm-associated antigen 8 that is encoded in the genome of human.


name: BAG1_HUMAN BAG family molecular chaperone regulator 1 (sprot)

description: A BAG family molecular chaperone regulator 1 that is encoded in the genome of human.


name: PROL1_HUMAN Opiorphin prepropeptide (sprot)

description: An opiorphin prepropeptide that is encoded in the genome of human.


name: ATF6B_HUMAN Cyclic AMP-dependent transcription factor ATF-6 beta (sprot)

description: A cyclic AMP-dependent transcription factor ATF-6 beta that is encoded in the genome of human.


name: RNF5_HUMAN E3 ubiquitin-protein ligase RNF5 (sprot)

description: An E3 ubiquitin-protein ligase RNF5 that is encoded in the genome of human.


name: PLCA_HUMAN 1-acyl-sn-glycerol-3-phosphate acyltransferase alpha (sprot)

description: A 1-acyl-sn-glycerol-3-phosphate acyltransferase alpha that is encoded in the genome of human.


name: EGFL8_HUMAN Epidermal growth factor-like protein 8 (sprot)

description: An epidermal growth factor-like protein 8 that is encoded in the genome of human.


name: PRRT1_HUMAN Proline-rich transmembrane protein 1 (sprot)

description: A proline-rich transmembrane protein 1 that is encoded in the genome of human.


name: PTN18_HUMAN Tyrosine-protein phosphatase non-receptor type 18 (sprot)

description: A tyrosine-protein phosphatase non-receptor type 18 that is encoded in the genome of human.


name: SMR3A_HUMAN Submaxillary gland androgen-regulated protein 3A (sprot)

description: A submaxillary gland androgen-regulated protein 3A that is encoded in the genome of human.


name: DUS9_HUMAN Dual specificity protein phosphatase 9 (sprot)

description: A dual specificity protein phosphatase 9 that is encoded in the genome of human.


name: FOXC2_HUMAN Forkhead box protein C2 (sprot)

description: A forkhead box protein C2 that is encoded in the genome of human.


PKP2_HUMAN Plakophilin-2 (sprot)

A plakophilin-2 that is encoded in the genome of human.


name: maintenance of protein localization at cell tip

description: Any process in which localization of a protein is maintained at the cell tip.


SH3G1_HUMAN Endophilin-A2 (sprot)

An endophilin-A2 that is encoded in the genome of human.


SH3G2_HUMAN Endophilin-A1 (sprot)

An endophilin-A1 that is encoded in the genome of human.


SH3G3_HUMAN Endophilin-A3 (sprot)

An endophilin-A3 that is encoded in the genome of human.


name: ADAM2_HUMAN Disintegrin and metalloproteinase domain-containing protein 2 (sprot)

description: A disintegrin and metalloproteinase domain-containing protein 2 that is encoded in the genome of human.


name: CITE1_HUMAN Cbp/p300-interacting transactivator 1 (sprot)

description: A Cbp/p300-interacting transactivator 1 that is encoded in the genome of human.


response to interleukin-11

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-11 stimulus.


name: CITE2_HUMAN Cbp/p300-interacting transactivator 2 (sprot)

description: A Cbp/p300-interacting transactivator 2 that is encoded in the genome of human.


cranial nerve morphogenesis

description: The process in which the anatomical structure of the cranial nerves are generated and organized. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions.


name: RARR2_HUMAN Retinoic acid receptor responder protein 2 (sprot)

description: A retinoic acid receptor responder protein 2 that is encoded in the genome of human.


MYOC_HUMAN Myocilin (sprot)

A myocilin that is encoded in the genome of human.


skeletal muscle hypertrophy

description: The enlargement or overgrowth of all or part of an organ due to an increase in size (not length) of individual muscle fibers without cell division. In the case of skeletal muscle cells this happens due to the additional synthesis of sarcomeric proteins and assembly of myofibrils.


name: TEP1_HUMAN Telomerase protein component 1 (sprot)

description: A telomerase protein component 1 that is encoded in the genome of human.


OMD_HUMAN Osteomodulin (sprot)

An osteomodulin that is encoded in the genome of human.


SEM3C_HUMAN Semaphorin-3C (sprot)

A semaphorin-3C that is encoded in the genome of human.


name: cardiac endothelial to mesenchymal transition

description: A transition where a cardiac endothelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell. Endocardial cells (specialized endothelial cells that line the heart) undergo EndMT, and give rise to mesenchymal cells necessary for proper heart development. EndMT, specifically generates valve progenitor cells that give rise to the mitral and tricuspid valves. EndMT also contributes to endocardial cushion formation, as well as to generation of cardiac fibroblasts and smooth muscle cells, but not cardiac myocytes.


name: VRK1_HUMAN Serine/threonine-protein kinase VRK1 (sprot)

description: A serine/threonine-protein kinase VRK1 that is encoded in the genome of human.


histone H2AX kinase activity

description: Catalysis of the transfer of a phosphate group to a histone variant H2AX.


name: GDF15_HUMAN Growth/differentiation factor 15 (sprot)

description: A growth/differentiation factor 15 that is encoded in the genome of human.


name: VGLL1_HUMAN Transcription cofactor vestigial-like protein 1 (sprot)

description: A transcription cofactor vestigial-like protein 1 that is encoded in the genome of human.


name: AKAP9_HUMAN A-kinase anchor protein 9 (sprot)

description: An A-kinase anchor protein 9 that is encoded in the genome of human.


name: G3ST1_HUMAN Galactosylceramide sulfotransferase (sprot)

description: A galactosylceramide sulfotransferase that is encoded in the genome of human.


galactosylceramide metabolic process

description: The chemical reactions and pathways involving galactosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of galactose by a ceramide group.


name: DPYL5_HUMAN Dihydropyrimidinase-related protein 5 (sprot)

description: A dihydropyrimidinase-related protein 5 that is encoded in the genome of human.


name: B9D2_HUMAN B9 domain-containing protein 2 (sprot)

description: A B9 domain-containing protein 2 that is encoded in the genome of human.


P2Y13_HUMAN P2Y purinoceptor 13 (sprot)

A P2Y purinoceptor 13 that is encoded in the genome of human.


APOL4_HUMAN Apolipoprotein L4 (sprot)

An apolipoprotein L4 that is encoded in the genome of human.


name: RSLBB_HUMAN Ras-like protein family member 11B (sprot)

description: A Ras-like protein family member 11B that is encoded in the genome of human.


name: NIPS1_HUMAN Protein NipSnap homolog 1 (sprot)

description: A protein NipSnap homolog 1 that is encoded in the genome of human.


name: DHRS9_HUMAN Dehydrogenase/reductase SDR family member 9 (sprot)

description: A dehydrogenase/reductase SDR family member 9 that is encoded in the genome of human.


racemase and epimerase activity

description: Catalysis of a reaction that alters the configuration of one or more chiral centers in a molecule.


name: DHB14_HUMAN 17-beta-hydroxysteroid dehydrogenase 14 (sprot)

description: A 17-beta-hydroxysteroid dehydrogenase 14 that is encoded in the genome of human.


name: CND3_HUMAN Condensin complex subunit 3 (sprot)

description: A condensin complex subunit 3 that is encoded in the genome of human.


name: ARP5L_HUMAN Actin-related protein 2/3 complex subunit 5-like protein (sprot)

description: An actin-related protein 2/3 complex subunit 5-like protein that is encoded in the genome of human.


name: MICU1_HUMAN Calcium uptake protein 1, mitochondrial (sprot)

description: A calcium uptake protein 1, mitochondrial that is encoded in the genome of human.


name: CG025_HUMAN UPF0415 protein C7orf25 (sprot)

description: A UPF0415 protein C7orf25 that is encoded in the genome of human.


F118B_HUMAN Protein FAM118B (sprot)

A protein FAM118B that is encoded in the genome of human.


name: HOP_HUMAN Homeodomain-only protein (sprot)

description: A homeodomain-only protein that is encoded in the genome of human.


SPI2B_HUMAN Spindlin-2B (sprot)

A spindlin-2B that is encoded in the genome of human.


name: PAIP2_HUMAN Polyadenylate-binding protein-interacting protein 2 (sprot)

description: A polyadenylate-binding protein-interacting protein 2 that is encoded in the genome of human.


name: SIN1_HUMAN Target of rapamycin complex 2 subunit MAPKAP1 (sprot)

description: A target of rapamycin complex 2 subunit MAPKAP1 that is encoded in the genome of human.


name: RBM4B_HUMAN RNA-binding protein 4B (sprot)

description: An RNA-binding protein 4B that is encoded in the genome of human.


RETNB_HUMAN Resistin-like beta (sprot)

A resistin-like beta that is encoded in the genome of human.


name: KCD14_HUMAN BTB/POZ domain-containing protein KCTD14 (sprot)

description: A BTB/POZ domain-containing protein KCTD14 that is encoded in the genome of human.


name: SOSB1_HUMAN SOSS complex subunit B1 (sprot)

description: A SOSS complex subunit B1 that is encoded in the genome of human.


TICN3_HUMAN Testican-3 (sprot)

A testican-3 that is encoded in the genome of human.


name: ZFY21_HUMAN Zinc finger FYVE domain-containing protein 21 (sprot)

description: A zinc finger FYVE domain-containing protein 21 that is encoded in the genome of human.


name: KCNS3_HUMAN Potassium voltage-gated channel subfamily S member 3 (sprot)

description: A voltage-gated potassium channel KCNS3 that is encoded in the genome of human.


name: DDX50_HUMAN ATP-dependent RNA helicase DDX50 (sprot)

description: An ATP-dependent RNA helicase DDX50 that is encoded in the genome of human.


name: RM34_HUMAN Large ribosomal subunit protein bL34m (sprot)

description: A large ribosomal subunit protein bL34m that is encoded in the genome of human.


name: SMIM7_HUMAN Small integral membrane protein 7 (sprot)

description: A small integral membrane protein 7 that is encoded in the genome of human.


name: TREX2_HUMAN Three prime repair exonuclease 2 (sprot)

description: A three prime repair exonuclease 2 that is encoded in the genome of human.


name: PD1L2_HUMAN Programmed cell death 1 ligand 2 (sprot)

description: A programmed cell death 1 ligand 2 that is encoded in the genome of human.


name: RNZ2_HUMAN Zinc phosphodiesterase ELAC protein 2 (sprot)

description: A zinc phosphodiesterase ELAC protein 2 that is encoded in the genome of human.


tRNA-specific ribonuclease activity

description: Catalysis of the hydrolysis of phosphodiester bonds in tRNA molecules.


name: TRIR_HUMAN Telomerase RNA component interacting RNase (sprot)

description: A telomerase RNA component interacting RNase that is encoded in the genome of human.


name: USB1_HUMAN U6 snRNA phosphodiesterase 1 (sprot)

description: A U6 snRNA phosphodiesterase that is encoded in the genome of human.


name: poly(U)-specific exoribonuclease activity, producing 3' uridine cyclic phosphate ends

description: Catalysis of 3' exonucleolytic cleavage of poly(U), to form poly(U)-N containing a 3' uridine cyclic phosphate (U>P).


U6 snRNA 3'-end processing

description: Any process involved in forming the mature 3' end of a U6 snRNA molecule.


name: KR412_HUMAN Keratin-associated protein 4-12 (sprot)

description: A keratin-associated protein 4-12 that is encoded in the genome of human.


name: GRWD1_HUMAN Glutamate-rich WD repeat-containing protein 1 (sprot)

description: A glutamate-rich WD repeat-containing protein 1 that is encoded in the genome of human.


name: MACD1_HUMAN ADP-ribose glycohydrolase MACROD1 (sprot)

description: An ADP-ribose glycohydrolase MACROD1 that is encoded in the genome of human.


name: TCF25_HUMAN Ribosome quality control complex subunit TCF25 (sprot)

description: A ribosome quality control complex subunit TCF25 that is encoded in the genome of human.


name: regulation of protein K48-linked ubiquitination

description: Any process that modulates the rate, frequency or extent of protein K-48-linked ubiquitination, a protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 48 of the ubiquitin monomers, is added to a protein. K48-linked ubiquitination targets the substrate protein for degradation.


CMS1_HUMAN Protein CMSS1 (sprot)

A protein CMSS1 that is encoded in the genome of human.


name: SLX1_HUMAN Structure-specific endonuclease subunit SLX1 (sprot)

description: A structure-specific endonuclease subunit SLX1 that is encoded in the genome of human.


name: TBL1Y_HUMAN F-box-like/WD repeat-containing protein TBL1Y (sprot)

description: An F-box-like/WD repeat-containing protein TBL1Y that is encoded in the genome of human.


F110A_HUMAN Protein FAM110A (sprot)

A protein FAM110A that is encoded in the genome of human.


name: KLDC3_HUMAN Kelch domain-containing protein 3 (sprot)

description: A kelch domain-containing protein 3 that is encoded in the genome of human.


name: ECSIT_HUMAN Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial (sprot)

description: An evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial that is encoded in the genome of human.


regulation of oxidoreductase activity

description: Any process that modulates the frequency, rate or extent of oxidoreductase activity, the catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.


name: MEP50_HUMAN Methylosome protein WDR77 (sprot)

description: A methylosome protein WDR77 that is encoded in the genome of human.


name: HINFP_HUMAN Histone H4 transcription factor (sprot)

description: A histone H4 transcription factor that is encoded in the genome of human.


name: CYBC1_HUMAN Cytochrome b-245 chaperone 1 (sprot)

description: A cytochrome b-245 chaperone 1 that is encoded in the genome of human.


SOST_HUMAN Sclerostin (sprot)

A sclerostin that is encoded in the genome of human.


name: VKOR1_HUMAN Vitamin K epoxide reductase complex subunit 1 (sprot)

description: A vitamin K epoxide reductase complex subunit 1 that is encoded in the genome of human.


name: vitamin-K-epoxide reductase (warfarin-insensitive) activity

description: Catalysis of the reaction: 3-hydroxy-2-methyl-3-phytyl-2,3-dihydronaphthoquinone + oxidized dithiothreitol + H2O = 2,3-epoxy-2,3-dihydro-2-methyl-3-phytyl-1,4-naphthoquinone + 1,4-dithiothreitol.


name: DPH2_HUMAN 2-(3-amino-3-carboxypropyl)histidine synthase subunit 2 (sprot)

description: A 2-(3-amino-3-carboxypropyl)histidine synthase subunit 2 that is encoded in the genome of human.


description: Catalysis of the reaction S-adenosyl-L-methionine + L-histidine-[translation elongation factor 2] = S-methyl-5-thioadenosine + 2-[(3S)-3-amino-3-carboxypropyl]-L-histidine-[translation elongation factor 2].


name: RT63_HUMAN Large ribosomal subunit protein mL63 (sprot)

description: A large ribosomal subunit protein mL63 that is encoded in the genome of human.


name: MCHL2_HUMAN Putative pro-MCH-like protein 2 (sprot)

description: A putative pro-MCH-like protein 2 that is encoded in the genome of human.


name: KXDL1_HUMAN KxDL motif-containing protein 1 (sprot)

description: A KxDL motif-containing protein 1 that is encoded in the genome of human.


name: ANKMT_HUMAN Adenine nucleotide translocase lysine N-methyltransferase (sprot)

description: An adenine nucleotide translocase lysine N-methyltransferase that is encoded in the genome of human.


name: TBA1C_HUMAN Tubulin alpha-1C chain (sprot)

description: A tubulin alpha-1C chain that is encoded in the genome of human.


SELS_HUMAN Selenoprotein S (sprot)

A selenoprotein S that is encoded in the genome of human.


name: regulation of nitric oxide metabolic process

description: Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nitric oxide, nitrogen monoxide (NO), a colorless gas only slightly soluble in water.


Derlin-1-VIMP complex

description: A protein complex containing, in mammals, Derlin-1 and VCP-interacting membrane protein (VIMP). The complex links the p97/VCP-containing ATPase complex with Derlin-1 during translocation of protein substrates from the endoplasmic reticulum to the cytosol for degradation by the cytosolic proteasome.


APOL2_HUMAN Apolipoprotein L2 (sprot)

An apolipoprotein L2 that is encoded in the genome of human.


name: BCL7B_HUMAN B-cell CLL/lymphoma 7 protein family member B (sprot)

description: A B-cell CLL/lymphoma 7 protein family member B that is encoded in the genome of human.


name: SENP7_HUMAN Sentrin-specific protease 7 (sprot)

description: A sentrin-specific protease 7 that is encoded in the genome of human.


name: MBB1A_HUMAN Myb-binding protein 1A (sprot)

description: A Myb-binding protein 1A that is encoded in the genome of human.


SYT3_HUMAN Synaptotagmin-3 (sprot)

A synaptotagmin-3 that is encoded in the genome of human.


name: NUD12_HUMAN NAD-capped RNA hydrolase NUDT12 (sprot)

description: An NAD-capped RNA hydrolase NUDT12 that is encoded in the genome of human.


name: AIF1L_HUMAN Allograft inflammatory factor 1-like (sprot)

description: An allograft inflammatory factor 1-like that is encoded in the genome of human.


name: E2AK1_HUMAN Eukaryotic translation initiation factor 2-alpha kinase 1 (sprot)

description: A eukaryotic translation initiation factor 2-alpha kinase 1 that is encoded in the genome of human.


name: negative regulation of translational initiation by iron

description: Any process involving iron that stops, prevents or reduces the rate of translational initiation.


name: negative regulation of hemoglobin biosynthetic process

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hemoglobin, an oxygen carrying, conjugated protein containing four heme groups and globin.


name: CCDC3_HUMAN Coiled-coil domain-containing protein 3 (sprot)

description: A coiled-coil domain-containing protein 3 that is encoded in the genome of human.


name: SGIP1_HUMAN SH3-containing GRB2-like protein 3-interacting protein 1 (sprot)

description: An SH3-containing GRB2-like protein 3-interacting protein 1 that is encoded in the genome of human.


name: SLF1_HUMAN SMC5-SMC6 complex localization factor protein 1 (sprot)

description: An SMC5-SMC6 complex localization factor protein 1 that is encoded in the genome of human.


name: PSD2_HUMAN PH and SEC7 domain-containing protein 2 (sprot)

description: A PH and SEC7 domain-containing protein 2 that is encoded in the genome of human.


name: NRIP2_HUMAN Nuclear receptor-interacting protein 2 (sprot)

description: A nuclear receptor-interacting protein 2 that is encoded in the genome of human.


name: TMM47_HUMAN Transmembrane protein 47 (sprot)

description: A transmembrane protein 47 that is encoded in the genome of human.


name: LPIN3_HUMAN Phosphatidate phosphatase LPIN3 (sprot)

description: A phosphatidate phosphatase LPIN3 that is encoded in the genome of human.


name: FERM1_HUMAN Fermitin family homolog 1 (sprot)

description: A fermitin family homolog 1 that is encoded in the genome of human.


negative regulation of timing of anagen

description: Any process that stops, prevents, or reduces the frequency, rate or extent of timing of anagen, the growth phase of the hair cycle.


FA83C_HUMAN Protein FAM83C (sprot)

A protein FAM83C that is encoded in the genome of human.


name: MGME1_HUMAN Mitochondrial genome maintenance exonuclease 1 (sprot)

description: A mitochondrial genome maintenance exonuclease 1 that is encoded in the genome of human.


name: BPIA3_HUMAN BPI fold-containing family A member 3 (sprot)

description: A BPI fold-containing family A member 3 that is encoded in the genome of human.


name: GORS1_HUMAN Golgi reassembly-stacking protein 1 (sprot)

description: A Golgi reassembly-stacking protein 1 that is encoded in the genome of human.


name: RTP3_HUMAN Receptor-transporting protein 3 (sprot)

description: A receptor-transporting protein 3 that is encoded in the genome of human.


PRS27_HUMAN Serine protease 27 (sprot)

A serine protease 27 that is encoded in the genome of human.


name: HSPB9_HUMAN Heat shock protein beta-9 (sprot)

description: A heat shock protein beta-9 that is encoded in the genome of human.


HEPH_HUMAN Hephaestin (sprot)

A hephaestin that is encoded in the genome of human.


name: FYCO1_HUMAN FYVE and coiled-coil domain-containing protein 1 (sprot)

description: A FYVE and coiled-coil domain-containing protein 1 that is encoded in the genome of human.


name: ODC_HUMAN Mitochondrial 2-oxodicarboxylate carrier (sprot)

description: A mitochondrial 2-oxodicarboxylate carrier that is encoded in the genome of human.


name: mitochondrial alpha-ketoglutarate transmembrane transport

description: The process in which alpha-ketoglutarate is transported across a mitochondrial membrane, into or out of the mitochondrion.


CSTN3_HUMAN Calsyntenin-3 (sprot)

A calsyntenin-3 that is encoded in the genome of human.


name: COE4_HUMAN Transcription factor COE4 (sprot)

description: A transcription factor COE4 that is encoded in the genome of human.


name: RHXF2_HUMAN Rhox homeobox family member 2 (sprot)

description: A rhox homeobox family member 2 that is encoded in the genome of human.


name: WFDC6_HUMAN WAP four-disulfide core domain protein 6 (sprot)

description: A WAP four-disulfide core domain protein 6 that is encoded in the genome of human.


name: DBND2_HUMAN Dysbindin domain-containing protein 2 (sprot)

description: A dysbindin domain-containing protein 2 that is encoded in the genome of human.


name: ST4A1_HUMAN Sulfotransferase 4A1 (sprot)

description: A sulfotransferase 4A1 that is encoded in the genome of human.


name: NEUL2_HUMAN Neuralized-like protein 2 (sprot)

description: A neuralized-like protein 2 that is encoded in the genome of human.


name: SPT25_HUMAN Spermatogenesis-associated protein 25 (sprot)

description: A spermatogenesis-associated protein 25 that is encoded in the genome of human.


name: ZSWM1_HUMAN Zinc finger SWIM domain-containing protein 1 (sprot)

description: A zinc finger SWIM domain-containing protein 1 that is encoded in the genome of human.


name: OCSTP_HUMAN Osteoclast stimulatory transmembrane protein (sprot)

description: An osteoclast stimulatory transmembrane protein that is encoded in the genome of human.


multinuclear osteoclast differentiation

description: The process in which a relatively unspecialized monocyte acquires the specialized features of a multinuclear osteoclast. An osteoclast is a specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue.


JPH2_HUMAN Junctophilin-2 (sprot)

A junctophilin-2 that is encoded in the genome of human.


name: regulation of cardiac muscle tissue development

description: Any process that modulates the frequency, rate or extent of cardiac muscle tissue development.


name: ACBD6_HUMAN Acyl-CoA-binding domain-containing protein 6 (sprot)

description: An acyl-CoA-binding domain-containing protein 6 that is encoded in the genome of human.


COR1B_HUMAN Coronin-1B (sprot)

A coronin-1B that is encoded in the genome of human.


name: CCD77_HUMAN Coiled-coil domain-containing protein 77 (sprot)

description: A coiled-coil domain-containing protein 77 that is encoded in the genome of human.


name: ZN559_HUMAN Zinc finger protein 559 (sprot)

description: A zinc finger protein 559 that is encoded in the genome of human.


name: LSMD1_HUMAN N-alpha-acetyltransferase 38, NatC auxiliary subunit (sprot)

description: An N-alpha-acetyltransferase 38, NatC auxiliary subunit that is encoded in the genome of human.


name: TXD17_HUMAN Thioredoxin domain-containing protein 17 (sprot)

description: A thioredoxin domain-containing protein 17 that is encoded in the genome of human.


name: PIGQ_HUMAN Phosphatidylinositol N-acetylglucosaminyltransferase subunit Q (sprot)

description: A phosphatidylinositol N-acetylglucosaminyltransferase subunit Q that is encoded in the genome of human.


name: PLCD4_HUMAN 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 (sprot)

description: A 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 that is encoded in the genome of human.


BUD13_HUMAN BUD13 homolog (sprot)

A BUD13 homolog that is encoded in the genome of human.


RES complex

description: A protein complex that is required for efficient splicing, and prevents leakage of unspliced pre-mRNAs from the nucleus (named for pre-mRNA REtention and Splicing). In Saccharomyces, the complex consists of Ist3p, Bud13p, and Pml1p.


name: CPPED_HUMAN Serine/threonine-protein phosphatase CPPED1 (sprot)

description: A serine/threonine-protein phosphatase CPPED1 that is encoded in the genome of human.


name: VPS25_HUMAN Vacuolar protein-sorting-associated protein 25 (sprot)

description: A vacuolar protein-sorting-associated protein 25 that is encoded in the genome of human.


name: SH23A_HUMAN SH2 domain-containing protein 3A (sprot)

description: An SH2 domain-containing protein 3A that is encoded in the genome of human.


name: ZN251_HUMAN Zinc finger protein 251 (sprot)

description: A zinc finger protein 251 that is encoded in the genome of human.


name: ZNT2_HUMAN Proton-coupled zinc antiporter SLC30A2 (sprot)

description: A proton-coupled zinc antiporter SLC30A2 that is encoded in the genome of human.


zinc ion import into zymogen granule

description: The directed import of zinc(2+) from the cytosol, across an organelle membrane, into a zymogen granule.


zinc ion import into mitochondrion

description: The directed import of zinc(2+) from the cytosol, across an organelle membrane, into a mitochondrion.


name: RM45_HUMAN Large ribosomal subunit protein mL45 (sprot)

description: A large ribosomal subunit protein mL45 that is encoded in the genome of human.


name: CG050_HUMAN Uncharacterized protein C7orf50 (sprot)

description: An uncharacterized protein C7orf50 that is encoded in the genome of human.


name: TIRR_HUMAN Tudor-interacting repair regulator protein (sprot)

description: A tudor-interacting repair regulator protein that is encoded in the genome of human.


name: MESP1_HUMAN Mesoderm posterior protein 1 (sprot)

description: A mesoderm posterior protein 1 that is encoded in the genome of human.


sinus venosus morphogenesis

description: The process in which the sinus venosus is generated and organized. The sinus venosus is a heart chamber attached to the atrium on the venous side of the embryonic heart.


cardioblast anterior-lateral migration

description: The orderly movement of a cardioblast toward the head and laterally to form the heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.


name: negative regulation of endodermal cell fate specification

description: Any process that restricts, stops or prevents a cell from specifying into an endoderm cell.


sinoatrial node cell differentiation

description: The process in which a relatively unspecialized cell acquires specialized features of a sinoatrial (SA) node cell. SA node cells are pacemaker cells that are found in the sinoatrial node.


name: cardioblast migration to the midline involved in heart field formation

description: The orderly movement of a cardioblast toward the midline to form the heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.


name: positive regulation of hepatocyte differentiation

description: Any process that activates or increases the rate or extent of hepatocyte differentiation.


name: REEP2_HUMAN Receptor expression-enhancing protein 2 (sprot)

description: A receptor expression-enhancing protein 2 that is encoded in the genome of human.


name: MXRA8_HUMAN Matrix remodeling-associated protein 8 (sprot)

description: A matrix remodeling-associated protein 8 that is encoded in the genome of human.


name: establishment of glial blood-brain barrier

description: Establishment of the glial barrier between the blood and the brain. The glial cells in the brain are packed tightly together preventing the passage of most molecules from the blood into the brain. Only lipid soluble molecules or those that are actively transported can pass through the blood-brain barrier.


name: LZTS2_HUMAN Leucine zipper putative tumor suppressor 2 (sprot)

description: A leucine zipper putative tumor suppressor 2 that is encoded in the genome of human.


primary ureteric bud growth

description: The process in which the primary ureteric bud grows along its axis dorsally toward the metanephric blastema.


name: CAB45_HUMAN 45 kDa calcium-binding protein (sprot)

description: A 45 kDa calcium-binding protein that is encoded in the genome of human.


zymogen granule exocytosis

description: The release of intracellular molecules contained within the zymogen granule by fusion of the granule with the plasma membrane of the oocyte, requiring calcium ions.


name: SRSF8_HUMAN Serine/arginine-rich splicing factor 8 (sprot)

description: A serine/arginine-rich splicing factor 8 that is encoded in the genome of human.


name: SC22C_HUMAN Vesicle-trafficking protein SEC22c (sprot)

description: A vesicle-trafficking protein SEC22c that is encoded in the genome of human.


name: TM2D3_HUMAN TM2 domain-containing protein 3 (sprot)

description: A TM2 domain-containing protein 3 that is encoded in the genome of human.


name: OVOL2_HUMAN Transcription factor Ovo-like 2 (sprot)

description: A transcription factor Ovo-like 2 that is encoded in the genome of human.


name: PDD2L_HUMAN Programmed cell death protein 2-like (sprot)

description: A programmed cell death protein 2-like that is encoded in the genome of human.


name: PAAF1_HUMAN Proteasomal ATPase-associated factor 1 (sprot)

description: A proteasomal ATPase-associated factor 1 that is encoded in the genome of human.


name: FDXA1_HUMAN Ferredoxin-fold anticodon-binding domain-containing protein 1 (sprot)

description: A ferredoxin-fold anticodon-binding domain-containing protein 1 that is encoded in the genome of human.


name: PYM1_HUMAN Partner of Y14 and mago (sprot)

description: A protein wibg that is encoded in the genome of human.


exon-exon junction complex disassembly

description: The disaggregation of an exon-exon junction complex into its constituent components.


PYGO2_HUMAN Pygopus homolog 2 (sprot)

A pygopus homolog 2 that is encoded in the genome of human.


name: histone acetyltransferase regulator activity

description: Binds to and modulates the activity of histone acetyltransferase.


name: NUD22_HUMAN Uridine diphosphate glucose pyrophosphatase NUDT22 (sprot)

description: A uridine diphosphate glucose pyrophosphatase NUDT22 that is encoded in the genome of human.


name: CF300_HUMAN Cilia- and flagella-associated protein 300 (sprot)

description: A cilia- and flagella-associated protein 300 that is encoded in the genome of human.


ORAI3_HUMAN Protein orai-3 (sprot)

A protein orai-3 that is encoded in the genome of human.


name: MIC25_HUMAN MICOS complex subunit MIC25 (sprot)

description: A MICOS complex subunit MIC25 that is encoded in the genome of human.


name: FSP1_HUMAN Ferroptosis suppressor protein 1 (sprot)

description: A ferroptosis suppressor protein 1 that is encoded in the genome of human.


name: ZKSC3_HUMAN Zinc finger protein with KRAB and SCAN domains 3 (sprot)

description: A zinc finger protein with KRAB and SCAN domains 3 that is encoded in the genome of human.


name: PGAP4_HUMAN Post-GPI attachment to proteins factor 4 (sprot)

description: A post-GPI attachment to proteins factor 4 that is encoded in the genome of human.


name: ADPGK_HUMAN ADP-dependent glucokinase (sprot)

description: An ADP-dependent glucokinase that is encoded in the genome of human.


ADP-specific glucokinase activity

description: Catalysis of the reaction: ADP + D-glucose = AMP + D-glucose 6-phosphate.


name: glycolytic process through glucose-6-phosphate

description: The chemical reactions and pathways resulting in the breakdown of a carbohydrate into pyruvate, occurring through a glucose-6-phosphate intermediate, with the concomitant production of a small amount of ATP.


name: GPTC1_HUMAN G patch domain-containing protein 1 (sprot)

description: A G patch domain-containing protein 1 that is encoded in the genome of human.


name: RHG09_HUMAN Rho GTPase-activating protein 9 (sprot)

description: A Rho GTPase-activating protein 9 that is encoded in the genome of human.


name: RIOK1_HUMAN Serine/threonine-protein kinase RIO1 (sprot)

description: A serine/threonine-protein kinase RIO1 that is encoded in the genome of human.


methyltransferase complex

description: A protein complex that possesses methyltransferase activity.


name: LARP6_HUMAN La-related protein 6 (sprot)

description: A La-related protein 6 that is encoded in the genome of human.


name: UQCC2_HUMAN Ubiquinol-cytochrome c reductase complex assembly factor 2 (sprot)

description: A ubiquinol-cytochrome c reductase complex assembly factor 2 that is encoded in the genome of human.


name: MIEN1_HUMAN Migration and invasion enhancer 1 (sprot)

description: A migration and invasion enhancer 1 that is encoded in the genome of human.


LLPH_HUMAN Protein LLP homolog (sprot)

A protein LLP that is encoded in the genome of human.


name: basal RNA polymerase II transcription machinery binding

description: Binding to a component of the basal transcription machinery for RNA polymerase II which is composed of the RNA polymerase II core enzyme, a multisubunit eukaryotic nuclear RNA polymerase typically composed of twelve subunits, and the basal RNA polymerase II transcription factors, the minimal set of factors required for formation of the preinitiation complex (PIC) by the RNA polymerase.


name: ZNG1A_HUMAN Zinc-regulated GTPase metalloprotein activator 1A (sprot)

description: A zinc-regulated GTPase metalloprotein activator 1A that is encoded in the genome of human.


name: SLD5_HUMAN DNA replication complex GINS protein SLD5 (sprot)

description: A DNA replication complex GINS protein SLD5 that is encoded in the genome of human.


name: TCAL7_HUMAN Transcription elongation factor A protein-like 7 (sprot)

description: A transcription elongation factor A protein-like 7 that is encoded in the genome of human.


name: UTP23_HUMAN rRNA-processing protein UTP23 homolog (sprot)

description: An rRNA-processing protein UTP23 that is encoded in the genome of human.


name: SWET1_HUMAN Sugar transporter SWEET1 (sprot)

description: A sugar transporter SWEET1 that is encoded in the genome of human.


name: glucoside transmembrane transporter activity

description: Enables the transfer of glucosides from one side of a membrane to the other. Glucosides are glycosides in which the sugar group is a glucose residue.


glucoside transport

description: The directed movement of glucosides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Glucosides are glycosides in which the sugar group is a glucose residue.


name: SIKE1_HUMAN Suppressor of IKBKE 1 (sprot)

description: A suppressor of IKK-epsilon that is encoded in the genome of human.


name: PELO_HUMAN Protein pelota homolog (sprot)

description: A protein pelota that is encoded in the genome of human.


name: nuclear-transcribed mRNA catabolic process, non-stop decay

description: The chemical reactions and pathways resulting in the breakdown of the transcript body of a nuclear-transcribed mRNA that is lacking a stop codon.


RNA surveillance

description: A process that identifies and degrades defective or aberrant RNAs.


Dom34-Hbs1 complex

description: A protein complex consisting of one subunit known as Dom34 or Pelota that has similarity to translation termination factor eRF1, and another subunit, Hbs1, that is a GTPase with similarity to translation termination factor eRF3. The Dom34-Hbs1 complex has a role in cotranslational mRNA quality control by promoting ribosomal subunit dissociation and peptidyl-tRNA release when translation is stalled, facilitating no-go decay and nonstop decay.


name: PSF3_HUMAN DNA replication complex GINS protein PSF3 (sprot)

description: A DNA replication complex GINS protein PSF3 that is encoded in the genome of human.


name: PXL2A_HUMAN Peroxiredoxin-like 2A (sprot)

description: A peroxiredoxin-like 2A that is encoded in the genome of human.


name: WDR83_HUMAN WD repeat domain-containing protein 83 (sprot)

description: A mitogen-activated protein kinase organizer 1 that is encoded in the genome of human.


name: S39A3_HUMAN Zinc transporter ZIP3 (sprot)

description: A zinc transporter ZIP3 that is encoded in the genome of human.


name: TRI56_HUMAN E3 ubiquitin-protein ligase TRIM56 (sprot)

description: An E3 ubiquitin-protein ligase TRIM56 that is encoded in the genome of human.


name: CENPK_HUMAN Centromere protein K (sprot)

description: A centromere protein K that is encoded in the genome of human.


name: APC13_HUMAN Anaphase-promoting complex subunit 13 (sprot)

description: An anaphase-promoting complex subunit 13 that is encoded in the genome of human.


name: ERP44_HUMAN Endoplasmic reticulum resident protein 44 (sprot)

description: An endoplasmic reticulum resident protein 44 that is encoded in the genome of human.


name: ZN649_HUMAN Zinc finger protein 649 (sprot)

description: A zinc finger protein 649 that is encoded in the genome of human.


name: ZN670_HUMAN Zinc finger protein 670 (sprot)

description: A zinc finger protein 670 that is encoded in the genome of human.


LXN_HUMAN Latexin (sprot)

A latexin that is encoded in the genome of human.


name: ZPBP1_HUMAN Zona pellucida-binding protein 1 (sprot)

description: A zona pellucida-binding protein 1 that is encoded in the genome of human.


name: S35A5_HUMAN UDP-sugar transporter protein SLC35A5 (sprot)

description: A UDP-sugar transporter protein SLC35A5 that is encoded in the genome of human.


name: TTYH2_HUMAN Protein tweety homolog 2 (sprot)

description: A protein tweety homolog 2 that is encoded in the genome of human.


name: TM175_HUMAN Endosomal/lysosomal proton channel TMEM175 (sprot)

description: An endosomal/lysosomal proton channel TMEM175 that is encoded in the genome of human.


name: ATGA1_HUMAN Autophagy-related protein 101 (sprot)

description: An autophagy-related protein 101 that is encoded in the genome of human.


name: NOL10_HUMAN Nucleolar protein 10 (sprot)

description: A nucleolar protein 10 that is encoded in the genome of human.


name: RHNO1_HUMAN RAD9, HUS1, RAD1-interacting nuclear orphan protein 1 (sprot)

description: A RAD9, HUS1, RAD1-interacting nuclear orphan protein 1 that is encoded in the genome of human.


name: NTPCR_HUMAN Cancer-related nucleoside-triphosphatase (sprot)

description: A cancer-related nucleoside-triphosphatase that is encoded in the genome of human.


name: TMM79_HUMAN Transmembrane protein 79 (sprot)

description: A transmembrane protein 79 that is encoded in the genome of human.


cuticle development

description: The chemical reactions and pathways resulting in the formation of a cuticle, the outer layer of some animals and plants, which acts to prevent water loss.


name: HERP2_HUMAN Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 2 protein (sprot)

description: A homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 2 protein that is encoded in the genome of human.


name: GDAH_HUMAN Guanidino acid hydrolase, mitochondrial (sprot)

description: A guanidino acid hydrolase, mitochondrial that is encoded in the genome of human.


agmatinase activity

description: Catalysis of the reaction: agmatine + H2O = putrescine + urea.


guanidinobutyrase activity

description: Catalysis of the reaction: 4-guanidinobutanoate + H2O = 4-aminobutanoate + urea.


guanidinopropionase activity

description: Catalysis of the reaction: 3-guanidinopropanoate + H2O = beta-alanine + urea.


name: SMAKA_HUMAN Small membrane A-kinase anchor protein (sprot)

description: A small membrane A-kinase anchor protein that is encoded in the genome of human.


name: TIM29_HUMAN Mitochondrial import inner membrane translocase subunit Tim29 (sprot)

description: A mitochondrial import inner membrane translocase subunit Tim29 that is encoded in the genome of human.


name: BTBDA_HUMAN BTB/POZ domain-containing protein 10 (sprot)

description: A BTB/POZ domain-containing protein 10 that is encoded in the genome of human.


name: PADC1_HUMAN Protease-associated domain-containing protein 1 (sprot)

description: A protease-associated domain-containing protein 1 that is encoded in the genome of human.


name: ZNF2_HUMAN Zinc finger protein 2 (sprot)

description: A zinc finger protein 2 that is encoded in the genome of human.


RTBDN_HUMAN Retbindin (sprot)

A retbindin that is encoded in the genome of human.