negative regulation of hypersensitivity

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of hypersensitivity.


name: perturbation of platelet aggregation in another organism

category: biolink:BiologicalProcess biolink:Occurrent biolink:OntologyClass biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: The process in which an organism effects a change that affects platelet aggregation in another organism. Platelet aggregation is the adhesion of one platelet to one or more other platelets via adhesion molecules.


positive regulation of sterol transport

description: Any process that activates or increases the frequency, rate or extent of the directed movement of sterols into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


category: biolink:MolecularActivity biolink:Occurrent biolink:OntologyClass biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: Catalysis of the reaction: 3-hydroxy-2-methylquinolin-4(1H)-one + H+ + O2 = N-acetylanthranilate + CO.


name: compound eye cone cell fate specification

description: The process in which a cell becomes capable of differentiating autonomously into a compound eye cone cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.


Rohon-Beard neuron differentiation

description: The process in which a relatively unspecialized cell acquires the specialized features of a Rohon-Beard neuron.


name: symbiont-mediated suppression of host exocytosis

description: A process in which a symbiont inhibits or disrupts the normal execution of  host exocytosis. The host is defined as the larger of the organisms involved in a symbiotic interaction.


name: positive regulation of vascular associated smooth muscle cell migration

description: Any process that activates or increases the frequency, rate or extent of vascular associated smooth muscle cell migration.


ferredoxin-NADP+ reductase activity

description: Catalysis of the reaction: reduced ferredoxin + NADP+ = oxidized ferredoxin + NADPH + H+.


salicylate 5-hydroxylase activity

description: Catalysis of the reaction: salicylate + O2 + NAD(P)H + H+ = gentisate + H2O + NAD(P)+.


name: specification of pronephric tubule identity

description: The process in which the tubules arranged along the proximal/distal axis of the pronephric nephron acquire their identity.


name: regulation of cAMP/PKA signal transduction

description: Any process that modulates the frequency, rate or extent of cAMP/PKA signal transduction.


regulation of myoblast differentiation

description: Any process that modulates the frequency, rate or extent of myoblast differentiation. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.


D-arabinokinase activity

description: Catalysis of the reaction: D-arabinose + ATP = D-arabinose 5-phosphate + ADP.


name: peripheral nervous system myelin formation

description: The process in which the wraps of cell membrane that constitute myelin are laid down around an axon by Schwann cells in the peripheral nervous system.


name: negative regulation of apoptotic process involved in development

description: Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in development.


protein histidine kinase activity

description: Catalysis of the reaction: ATP + protein L-histidine = ADP + protein phospho-L-histidine.


muramyl dipeptide binding

description: Interacting selectively and non-covalently, in a non-covalent manner, with muramyl dipeptide; muramyl dipeptide is derived from peptidoglycan.


name: 4-aminobenzoate amino acid synthetase activity

description: Catalysis of the reaction: 4-aminobenzoate + ATP + amino acid = 4-aminobenzoyl amino acid conjugate + AMP + diphosphate.


protopine 6-monooxygenase activity

description: Catalysis of the reaction: H+ + NADPH + O2 + protopine = 6-hydroxyprotopine + H2O + NADP+.


3-aminopropanal dehydrogenase activity

description: Catalysis of the reaction: 3-ammoniopropanal + NAD + H2O = 2 H+ + beta-alanine + NADH.


name: negative regulation of response to water deprivation

description: Any process that stops, prevents, or reduces the frequency, rate or extent of a response to water deprivation. Response to water deprivation is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a water deprivation stimulus, prolonged deprivation of water.


oncogene-induced cell senescence

description: A cellular senescence process associated with the dismantling of a cell as a response to oncogenic stress, such as the activation of the Ras oncogenic family.


cellular response to interleukin-11

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-11 stimulus.


limb spinous cell differentiation

description: The process in which a relatively unspecialized cell acquires specialized features of a limb epidermal spinous cell.


regulation of water channel activity

description: Any process that modulates the frequency, rate or extent of water channel activity.


asparagine-tRNA ligase activity

description: Catalysis of the reaction: L-asparagine + ATP + tRNA(Asn) = AMP + Asn-tRNA(Asn) + diphosphate + 2 H+.


name: base-excision repair, AP site formation via deaminated base removal

description: A base-excision repair, AP site formation process occurring via excision of a deaminated base.


protein autophosphorylation

description: The phosphorylation by a protein of one or more of its own amino acid residues (cis-autophosphorylation), or residues on an identical protein (trans-autophosphorylation).


name: positive regulation of nuclear migration along microtubule

description: Any process that activates or increases the frequency, rate or extent of nuclear migration along microtubule.


reproductive senescence

description: A life cycle stage during which the reproductive capacity and fitness of an organism declines.


name: acetate:monoatomic cation symporter activity

description: Enables the transfer of acetate from one side of a membrane to the other according to the reaction: acetate(out) + cation(out) = acetate(in) + cation(in).


name: 3-hydroxyphenyl propanoate transmembrane transporter activity

description: Enables the transfer of 3-hydroxyphenyl propanoate from one side of a membrane to the other.


eye pigment biosynthetic process

description: The chemical reactions and pathways resulting in the formation of eye pigments, any general or particular coloring matter in living organisms, found or utilized in the eye.


oocyte construction

description: The synthesis, deposition, and organization of the materials in a cell of an ovary; where the cell can then undergo meiosis and form an ovum. An example of this is found in Drosophila melanogaster.


thymidine phosphorylase activity

description: Catalysis of the reaction: thymidine + phosphate = thymine + 2-deoxy-D-ribose 1-phosphate.


pronuclear fusion

description: The merging of two pronuclei in a fertilized egg to fuse and produce a single zygotic genome.


cysteate synthase activity

description: Catalysis of the reaction: O-phospho-L-serine + sulfite + H+ = L-cysteate + phosphate.


sorocarp spore cell differentiation

description: The process in which a relatively unspecialized cell acquires specialized features of a sorocarp spore cell, a cell of the sorocarp sorus. A sorocarp is the fruiting body characteristic of certain cellular slime moulds (e.g., Dictyosteliida) and consists of both stalk and a sorus (spore mass).


beta-catenin-TCF complex assembly

description: The aggregation, arrangement and bonding together of a set of components to form a beta-catenin-TCF complex.


name: non-ribosomal peptide synthetase activity

description: Catalysis of a multistep reaction that produce non-ribosomal peptides. The key chain-building reaction, a C-N bond-forming reaction, involves the generation of the characteristic peptide bond by nucleophilic attack of the amino group of an amino-acyl donor unit covalently bound to a downstream peptidyl carrier protein module (amino acyl-S-PCP) on the acyl group of an upstream electrophilic acyl- or peptidyl acyl-S-PCP chain, catalyzed by a condensation (C) domain. Supplementing these core chain-elongation domains are variable numbers of auxiliary domains that are responsible for modification of the growing polypeptide chain by a small set of iterated reactions including epimerization, N-methylation, and heterocyclization.


name: positive regulation of foraging behavior

description: Any process that activates or increases the frequency, rate or extent of foraging behavior.


petal vascular tissue pattern formation

description: Vascular tissue pattern formation as it occurs in the petal of vascular plants.


negative regulation of ERK5 cascade

description: Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the ERK5 cascade.


delta-cuprenene synthase activity

description: Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = delta-cuprenene + diphosphoric acid.


cephalosporin C metabolic process

description: The chemical reactions and pathways involving cephalosporin C.


name: long-chain fatty-acyl-CoA catabolic process

description: The chemical reactions and pathways resulting in the breakdown of long-chain fatty-acyl-CoAs, any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a long-chain fatty-acyl group. A long-chain fatty acid has an aliphatic tail containing 13 to 22 carbons.


name: regulation of cellular response to glucose starvation

description: Any process that modulates the frequency, rate or extent of cellular response to glucose starvation.


name: intrinsic apoptotic signaling pathway in response to nitrosative stress

category: biolink:Pathway biolink:OntologyClass biolink:BiologicalProcess biolink:Occurrent biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: The series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced in response to nitrosative stress; a state often resulting from exposure to high levels of nitric oxide (NO) or the highly reactive oxidant peroxynitrite, which is produced following interaction of NO with superoxide anions.


description: Catalysis of the reaction: 3-methyl-2-oxo-1,2-dihydroquinoline + O2 + 2 H+ + 2 e- = H2O + 6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline.


name: L-arabinose 1-dehydrogenase (NAD+) activity

description: Catalysis of the reaction: L-arabinose + NAD+ = L-arabinono-1,4-lactone + NADH.


name: symbiont-mediated suppression of host immunoglobulin-mediated immune response

description: A process in which a symbiont interferes with, inhibits or disrupts the normal execution of the immunoglobulin-mediated immune response of the host organism. One common mechanism by which this happens is the direct inhibition of immunoglobulin activity, by direct binding or modification. The host is defined as the larger of the organisms involved in a symbiotic interaction.


DNA replication, removal of RNA primer

description: Removal of the Okazaki RNA primer from the lagging strand of replicating DNA, by a combination of the actions of DNA polymerase, DNA helicase and an endonuclease.


name: negative regulation of filamentous growth of a population of unicellular organisms in response to biotic stimulus

description: Any process that stops, prevents or reduces the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to biotic stimulus.


name: negative regulation of fatty acid transport

description: Any process that stops, prevents, or reduces the frequency, rate or extent of fatty acid transport.


name: central nervous system control of baroreceptor feedback

description: The neurological process in which nerve impulses arising in the aorta or the carotid sinuses travel to the medulla and reach the nucleus of tractus solaris.


name: acetyl-CoA biosynthetic process from pantothenate

description: The chemical reactions and pathways resulting in the formation of acetyl-CoA from pantothenate via phosphopantothenate and CoA.


sterigmatocystin catabolic process

description: The chemical reactions and pathways resulting in the breakdown of sterigmatocystin, a carcinogenic mycotoxin produced in high yields by strains of the common molds.


notochord morphogenesis

description: The process in which the anatomical structures of the notochord are generated and organized. The notochord is a mesoderm-derived structure located ventral of the developing nerve cord. In vertebrates, the notochord serves as a core around which other mesodermal cells form the vertebrae. In the most primitive chordates, which lack vertebrae, the notochord persists as a substitute for a vertebral column.


mannan catabolic process

description: The chemical reactions and pathways resulting in the breakdown of mannan, the main hemicellulose of soft (coniferous) wood, made up of D-mannose, D-glucose and D-galactose.


regulation of maltose transport

description: Any process that modulates the frequency, rate or extent of maltose transport.


prebend segment development

description: The process whose specific outcome is the progression of the prebend segment over time, from its formation to the mature structure. The prebend segment is a part of the descending thin limb that lies before the bend and exhibits permeabilities characteristic of the ascending limb, especially negligible water permeability.


neuroblast development

description: The process aimed at the progression of a neuroblast over time, from initial commitment of the cell to a specific state, to the mature neuroblast. It does not include processes where the neuroblast turns into a glial cell or a neuron.


oocyte fate commitment

description: The process in which the developmental fate of a cell becomes restricted such that it will develop into an oocyte.


icosanoid binding

description: Binding to icosanoids, any C20 polyunsaturated fatty acids or their derivatives, including the leukotrienes and the prostanoids.


description: Catalysis of the reaction: 4alpha-carboxy-stigmasta-7,24(241)-dien-3beta-ol + NAD = avenastenone + NADH + carbon dioxide.


retinoic acid metabolic process

description: The chemical reactions and pathways involving retinoic acid, one of the three components that makes up vitamin A.


name: regulation of calcium-dependent ATPase activity

description: Any process that modulates the frequency, rate or extent of calcium-dependent ATPase activity.


name: enzyme-directed rRNA pseudouridine synthesis

description: The intramolecular conversion of uridine to pseudouridine during ribosome biogenesis where the enzyme specifies the site that becomes pseudouridylated without using a guide RNA.


name: behavioral response to water deprivation

description: Any process that results in a change in the behavior of an organism as a result of deprivation of water.


stearic acid binding

description: Binding to stearic acid, the 18-carbon saturated fatty acid octadecanoic acid.


exon-exon junction complex assembly

description: The aggregation, arrangement and bonding together of a set of components to form an exon-exon junction complex.


name: T cell proliferation involved in immune response

description: The expansion of a T cell population by cell division as part of an immune response.


limonene 8-hydratase activity

description: Catalysis of the reaction: limonene + H2O = alpha-terpineol.


name: ventricular cardiac muscle tissue morphogenesis

description: The process in which the anatomical structures of cardiac ventricle muscle is generated and organized.


acetoacetate-CoA ligase activity

description: Catalysis of the reaction: acetoacetate + ATP + CoA = acetoacetyl-CoA + AMP + diphosphate + H+.


response to pyrimidine ribonucleotide

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pyrimidine ribonucleotide stimulus.


purine nucleoside biosynthetic process

description: The chemical reactions and pathways resulting in the formation of any purine nucleoside, one of a family of organic molecules consisting of a purine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside).


name: RNA NAD+-cap (NAD+-forming) hydrolase activity

description: Catalysis of the reaction: a 5'-end NAD+-phospho-ribonucleoside in mRNA + H2O = a 5'-end phospho-ribonucleoside in mRNA + H+ + NAD+.


name: negative regulation of pectin catabolic process

description: Any process that stops, prevents or reduces the frequency, rate or extent of pectin catabolic process.


protein-heme linkage

description: The covalent linkage of heme and a protein.


decylhomocitrate synthase activity

description: Catalysis of the reaction: 2-oxoglutarate + H2O + lauroyl-CoA = (3S,4S)-3-hydroxytetradecane-1,3,4-tricarboxylate + CoA + H+.


name: hydroxymethylglutaryl-CoA reductase (NADPH) activity

description: Catalysis of the reaction: (R)-mevalonate + CoA + 2 NADP+ = (S)-3-hydroxy-3-methylglutaryl-CoA + 2 H+ + 2 NADPH.


name: regulation of granulosa cell apoptotic process

description: Any process that modulates the frequency, rate or extent of granulosa cell apoptotic process.


name: negative regulation of lung blood pressure

description: The process that decreases the force with which blood travels through the lungs.


response to menaquinone

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a menaquinone (vitamin K2) stimulus.


name: regulation of cell chemotaxis to fibroblast growth factor

description: Any process that modulates the frequency, rate or extent of cell chemotaxis to fibroblast growth factor.


name: light-driven active monoatomic ion transmembrane transporter activity

description: Active transport of an ion across a membrane, driven by light.


cytotoxic T cell differentiation

description: The process in which a relatively unspecialized T cell acquires specialized features of a cytotoxic T cell.


name: negative regulation of hepatocyte growth factor receptor signaling pathway

description: Any process that stops, prevents or reduces the frequency, rate or extent of hepatocyte growth factor receptor signaling pathway.


neural rod formation

description: The formation of a solid rod of neurectoderm derived from the neural keel. The neural rod is roughly circular in cross section. Neural rod formation occurs during primary neurulation in teleosts.


photoreceptor cell maintenance

description: Any process preventing the degeneration of the photoreceptor, a specialized cell type that is sensitive to light.


photosystem I assembly

description: The aggregation, arrangement and bonding together of a set of components to form a photosystem I complex on the thylakoid membrane.


name: positive regulation of cyclodextrin catabolic process

description: Any process that activates or increases the frequency, rate or extent of cyclodextrin catabolic process.


name: Malpighian tubule tip cell differentiation

description: The process in which a relatively unspecialized cell acquires specialized features of a Malpighian tubule tip cell. A Malpighian tubule tip cell is a mitogenic signaling cell that controls the proliferation of its neighboring cells.


name: symbiont-mediated cytolysis of host cell

description: A process mediated by a symbiont that results in the death of a host cell by means of the rupture of cell membranes and the loss of cytoplasm. The host is defined as the larger of the organisms involved in a symbiotic interaction.


name: establishment of dense core granule localization

description: The directed movement of a dense core granule to a specific location.


motor neuron apoptotic process

description: Any apoptotic process in a motor neuron, an efferent neuron that passes from the central nervous system or a ganglion toward or to a muscle and conducts an impulse that causes movement.


mediator complex assembly

description: The aggregation, arrangement and bonding together of a set of components to form a mediator complex. The mediator complex is a protein complex that interacts with the carboxy-terminal domain of the largest subunit of RNA polymerase II and plays an active role in transducing the signal from a transcription factor to the transcriptional machinery. The Saccharomyces complex contains several identifiable subcomplexes: a head domain comprising Srb2, -4, and -5, Med6, -8, and -11, and Rox3 proteins; a middle domain comprising Med1, -4, and -7, Nut1 and -2, Cse2, Rgr1, Soh1, and Srb7 proteins; a tail consisting of Gal11p, Med2p, Pgd1p, and Sin4p; and a regulatory subcomplex comprising Ssn2, -3, and -8, and Srb8 proteins. Metazoan mediator complexes have similar modular structures and include homologs of yeast Srb and Med proteins.


intestinal hexose absorption

description: Uptake of hexoses, notably D-glucose, fructose, and galactose, into the blood by absorption from the small intestine.


3',2'-cyclic GMP-AMP synthase activity

description: Catalysis of the reaction: ATP + GTP = 2 diphosphate + cyclic G-P(3'-5')A-P(2'-5') (cyclic 3',2' GAMP).


name: compound eye retinal cell programmed cell death

description: Programmed cell death that occurs in the retina to remove excess cells between ommatidia, thus resulting in a hexagonal lattice, precise with respect to cell number and position surrounding each ommatidium.


name: netrin receptor activity involved in chemorepulsion

description: Combining with a netrin signal and transmitting the signal from one side of the membrane to the other to contribute to the directed movement of a motile cell away from a higher concentration of netrin.


long-chain-alcohol oxidase activity

description: Catalysis of the reaction: 2 long-chain alcohol + O2 = 2 long-chain aldehyde + 2 H2O.


Schwann cell migration

description: The orderly movement of a Schwann cell from one site to another. A Schwann cell is a glial cell that ensheathes axons of neuron in the peripheral nervous system and is necessary for their maintenance and function.


name: reorganization of cellular membranes to establish viral sites of replication

description: A process in intracellular membranes are reorganized by viral proteins that perturb membrane integrity and can cause an extensive rearrangement of cellular membranes, forming membranous webs, which are thought to be the site of replication or certain viruses, for example the HPV virus.


acylpyruvate hydrolase activity

description: Catalysis of the reaction: a 3-acylpyruvate + H2O = a carboxylate + pyruvate.


name: anaerobic purine nucleobase catabolic process

description: The anaerobic chemical reactions and pathways resulting in the breakdown of purine nucleobases, yielding energy in the form of ATP.


retinal cell apoptotic process

description: Any apoptotic process in a retinal cell.


AGC codon-amino acid adaptor activity

description: A triplet codon-amino acid adaptor activity that recognizes an AGC codon.


7-dehydrocholesterol reductase activity

description: Catalysis of the reaction: cholesterol + NADP+ = 7-dehydrocholesterol + H+ + NADPH.


postsynapse assembly

description: The aggregation, arrangement and bonding together of a set of components to form a postsynapse.


name: CMP-keto-3-deoxy-D-manno-octulosonic acid metabolic process

description: The chemical reactions and pathways involving CMP-keto-3-deoxy-D-manno-octulosonic acid, a substance composed of the acidic sugar 3-deoxy-D-manno-octulosonic acid in glycosidic linkage with cytidine monophosphate.


response to ultrasound

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ultrasonic stimulus.


cellular response to virus

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a virus.


exo-oligoalginate lyase activity

description: Catalysis of the cleavage of glycosidic bonds through a beta-elimination reaction on alginate, a linear polysaccharide consisting of guluronate (G) and mannuronate (M) as the monomer constituents. An oligoalginate is a linear polymer of two, three or four units of (1->4)-alpha-L-guluronic acid and beta-D-mannuronic acid, releasing monosaccharides with 4-deoxy-alpha-L-erythro-hex-4-enopyranuronosyl groups at their ends.


glycine catabolic process to creatine

description: The chemical reactions and pathways resulting in the breakdown of glycine into other compounds, including creatine.


name: formation of extrachromosomal circular DNA

description: Excision from the chromosome and circularization of a region of chromosomal DNA, generally, but not always, via homologous recombination between direct tandem repeats.


name: chrysanthemyl diphosphate synthase activity

description: Catalysis of the reaction: 2 dimethylallyl diphosphate = (R,R)-chrysanthemyl diphosphate + diphosphate.


name: positive regulation of cation transmembrane transport

description: Any process that activates or increases the frequency, rate or extent of cation transmembrane transport.


IAA-Ala conjugate hydrolase activity

description: Catalysis of the reaction: indole-3-acetyl-alanine + H2O = indole-3-acetate + L-alanine.


1,6-alpha-L-fucosidase activity

description: Catalysis of the hydrolysis of (1->6) linkages between alpha-L-fucose and N-acetyl-D-glucosamine in glycopeptides such as immunoglobulin G glycopeptide and fucosyl-asialo-agalacto-fetuin.


name: positive regulation of tolerance induction to self antigen

description: Any process that activates or increases the frequency, rate, or extent of tolerance induction to self antigen.


propionate CoA-transferase activity

description: Catalysis of the reaction: acetyl-CoA + propanoate = acetate + propanoyl-CoA.


name: protein-FAD linkage via 3'-(8alpha-FAD)-L-histidine

description: The formation of a protein-FAD linkage via 3'-(8-alpha-FAD)-L-histidine.


ether catabolic process

description: The chemical reactions and pathways resulting in the breakdown of ether.


vesicle scission

description: The membrane scission process that is the final step in the formation of a vesicle, leading to separation from its parent membrane. Vesicle scission involves the constriction of a neck-forming protein complex, consisting e.g. of dynamin, around the budded membrane, leading to vesicle closure during its separation from the parent membrane.


nonadec-1-ene metabolic process

description: The chemical reactions and pathways involving nonadec-1-ene.


name: negative regulation of inflammatory response to antigenic stimulus

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of an inflammatory response to an antigenic stimulus.


description: Catalysis of the reaction: 1,2-dihydroxyfluorene + O2 = 2-hydroxy-4-(2-oxo-1,3-dihydro-2H-inden-1-ylidene) but-2-enoic acid.


name: positive regulation of cytokinin-activated signaling pathway

description: Any process that activates or increases the frequency, rate or extent of cytokinin signaling.


cellular response to interleukin-15

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-15 stimulus.


creatinine metabolic process

description: The chemical reactions and pathways involving creatinine, 2-amino-1,5-dihydro-1-methyl-4H-imidazol-4-one, an end product of creatine metabolism and a normal constituent of urine.


name: molybdenum incorporation via L-aspartyl molybdenum bis(molybdopterin guanine dinucleotide)

description: The incorporation of molybdenum into a protein via L-aspartyl molybdenum bis(molybdopterin guanine dinucleotide).


description: Catalysis of the reaction: 3-hydroxyanthranilate + O2 = cis,cis-2-amino-3-(3-oxoprop-1-enyl)but-2-enedioate + H+.


rubredoxin-NAD(P)+ reductase activity

description: Catalysis of the reaction: reduced rubredoxin + NAD(P)+ = oxidized rubredoxin + NAD(P)H + H+.


name: cell-cell signaling involved in metanephros development

description: Any process that mediates the transfer of information from one cell to another and contributes to the progression of the metanephros over time, from its formation to the mature organ.


name: host response to induction by symbiont of tumor, nodule or growth in host

description: Any process that results in a change in the state or activity of a host cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the formation of an abnormal mass of cells in the host organism, induced by a symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction.


name: positive regulation of neuroinflammatory response

description: Any process that activates or increases the frequency, rate or extent of neuroinflammatory response.


neural fold elevation formation

description: The process in which the lateral borders of the neural plate begin to migrate upwards to form the neural folds, caused by the proliferation of the underlying mesoderm.


name: regulation of fungal-type cell wall biogenesis

description: Any process that modulates the process in which a cell wall is synthesized, aggregates, and bonds together. The fungal-type cell wall contains beta-glucan and may contain chitin.


name: positive regulation of regulation of vascular associated smooth muscle cell membrane depolarization

description: Any process that activates or increases the frequency, rate or extent of regulation of vascular smooth muscle cell membrane depolarization.


name: positive regulation of secondary cell wall biogenesis

description: Any process that activates or increases the frequency, rate or extent of secondary cell wall biogenesis.


pseurotin A catabolic process

description: The chemical reactions and pathways resulting in the breakdown of pseurotin A.


name: negative regulation of small intestinal transit

description: Any process that decreases the frequency, rate or extent of any small intestinal transit process, the migration of ingested material along the length of the small intestine.


description: Catalysis of the reaction: UDP-4-keto-rhamnose + NADPH = UDP-rhamnose + NADP+.


description: Catalysis of the transfer of sialyl residues alpha-2,3-linked to a beta galactosyl residue on the donor to form an alpha-2,3 linkage to a terminal beta galactosyl residue on the acceptor.


name: regulation of tetrapyrrole catabolic process

description: Any process that modulates the frequency, rate or extent of tetrapyrrole catabolic process.


name: negative regulation of acrosome reaction

description: Any process that stops, prevents or reduces the frequency, rate or extent of acrosome reaction.


gland development

description: The process whose specific outcome is the progression of a gland over time, from its formation to the mature structure. A gland is an organ specialised for secretion.


oligoribonucleotidase activity

description: Catalysis of the exonucleolytic cleavage of oligoribonucleotides to yield ribonucleoside 5'-phosphates.


regulation of memory T cell activation

description: Any process that modulates the frequency, rate or extent of memory T cell activation.


geraniol biosynthetic process

description: The chemical reactions and pathways resulting in the formation of geraniol.


dethiobiotin binding

description: Binding to dethiobiotin.


name: neural crest cell differentiation involved in parathyroid gland development

description: Any neural crest cell differentiation that is involved in parathyroid gland development.


inositol hexakisphosphate binding

description: Binding to inositol hexakisphosphate.


name: alanine:sodium symporter activity

description: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: alanine(out) + Na+(out) = alanine(in) + Na+(in).


name: envenomation resulting in slowing of activation kinetics of voltage-gated potassium channel in another organism

description: A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant slowing of the activation kinetics of the activity of a voltage-gated potassium channel in the bitten/stung organism.


o-pyrocatechuate decarboxylase activity

description: Catalysis of the reaction: 2,3-dihydroxybenzoate + H+ = catechol + CO2.


name: regulation of acute inflammatory response to non-antigenic stimulus

description: Any process that modulates the frequency, rate, or extent of an acute inflammatory response to a non-antigenic stimulus.


name: fungal-type cell wall (1->3)-alpha-glucan biosynthetic process

description: The chemical reactions and pathways resulting in the formation of (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in fungal-type cell walls, including those of ascospores.


haltere disc development

description: Progression of the haltere imaginal disc over time, from its initial formation through to its metamorphosis to form the adult capitellum, pedicel, haltere sclerite, metathoracic spiracle and metanotum.


name: glial cell projection elongation involved in axon ensheathment

description: The extension of a glial cell process or projection to wrap around an axon.


name: detection of hypoxic conditions in blood by chemoreceptor signaling

description: The process in which information about a lack of oxygen are received and are converted to a molecular signal by chemoreceptors in the carotid bodies and the aortic bodies.


name: negative regulation of mitotic cytokinetic process

description: Any process that stops, prevents or reduces the frequency, rate or extent of mitotic cytokinetic process.


mitochondrion DNA recombination

description: Any DNA recombination that takes place in mitochondrion.


name: positive regulation of (R)-carnitine transmembrane transport

description: Any process that activates or increases the frequency, rate or extent of (R)-carnitine transmembrane transport.


(S)-scoulerine biosynthetic process

description: The chemical reactions and pathways resulting in the formation of (S)-scoulerine.


description: Catalysis of the reaction: (6aR,11aR)-3,9-dihydroxypterocarpan + H+ + NADPH + O2 = (6aS,11aS)-3,6a,9-trihydroxypterocarpan + H2O + NADP+. (6aS,11aS)-3,6a,9-trihydroxypterocarpan is also known as (-)-glycinol.


description: Catalysis of the reaction: O2 + reduced [NADPH--hemoprotein reductase] + testosterone = 16beta,17beta-dihydroxyandrost-4-en-3-one + H+ + H2O + oxidized [NADPH--hemoprotein reductase].


COPII receptor activity

description: Binding specifically to a substance (cargo) to deliver it to a COPII transport vesicle. Cargo receptors span a membrane (either the plasma membrane or a vesicle membrane), binding simultaneously to cargo molecules and coat adaptors, to efficiently recruit soluble proteins to nascent vesicles.


hypochlorite binding

description: Binding to hypochlorite.


poly(U) RNA binding

description: Binding to a sequence of uracil residues in an RNA molecule.


response to ziprasidone

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ziprasidone stimulus. Ziprasidone is a piperazine compound having 1,2-benzothiazol-3-yl- and 2-(6-chloro-1,3-dihydro-2-oxindol-5-yl)ethyl substituents attached to the nitrogen atoms.


name: positive regulation of neuromuscular synaptic transmission

description: Any process that activates or increases the frequency, rate or extent of neuromuscular synaptic transmission.


high-affinity IgG receptor activity

description: Combining with high affinity with an immunoglobulin of an IgG isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


peptidyl-arginine methylation

description: The addition of a methyl group to an arginine residue in a protein.


description: Catalysis of the reaction: UDP-alpha-D-glucose + N-benzyladenine = H+ + benzyladenine-7-N-glucoside + UDP.


regulation of sporangium germination

description: Any process that modulates the frequency, rate or extent of sporangium germination.


name: lateral line nerve glial cell development

description: The process aimed at the progression of a lateral line glial cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.


name: trans-synaptic signaling by endocannabinoid

description: Cell-cell signaling in either direction across the synaptic cleft, mediated by an endocannabinoid ligand.


salicylaldehyde dehydrogenase activity

description: Catalysis of the reaction: salicylaldehyde + NAD+ + H2O = salicylate + NADH + H+.


cyanide catabolic process

description: The chemical reactions and pathways resulting in the breakdown of cyanide, NC-, the anion of hydrocyanic acid. Cyanide is a potent inhibitor of respiration.


tyramine biosynthetic process

description: The chemical reactions and pathways resulting in the formation of tyramine.


peptide pheromone maturation

description: The generation of a mature, active peptide pheromone via processes unique to its processing and modification. An example of this process is found in Saccharomyces cerevisiae.


cardiolipin metabolic process

description: The chemical reactions and pathways involving cardiolipin, 1,3-bis(3-phosphatidyl)glycerol.


name: negative regulation of pyloric antrum smooth muscle contraction

description: Any process that decreases the frequency, rate or extent of any pyloric antrum smooth muscle contraction.


name: deoxyribose phosphate biosynthetic process

description: The chemical reactions and pathways resulting in the formation of deoxyribose phosphate, the phosphorylated sugar 2-deoxy-erythro-pentose.


pyocyanin hydroxylase activity

description: Catalysis of the reaction: 5-methylphenazine-1-carboxylate + NADH + O2 + 2 H+ = pyocyanin + NAD + carbon dioxide + H2O.


description: Catalysis of the reaction: N-benzyloxycarbonylglycine + H2O + H+ = benzyl alcohol + CO2 + glycine.


farnesyltranstransferase activity

description: Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate + isopentenyl diphosphate = diphosphate + geranylgeranyl diphosphate.


name: regulation of nucleoside metabolic process

description: Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nucleosides.


name: 23S rRNA (adenosine(1067)-2'-O)-methyltransferase activity

description: Catalysis of the reaction: adenosine(1067) in 23S rRNA + S-adenosyl-L-methionine = 2'-O-methyladenosine(1067) in 23S rRNA + H+ + S-adenosyl-L-homocysteine.


name: VEGF-activated platelet-derived growth factor receptor-alpha signaling pathway

description: The series of molecular signals initiated by vascular endothelial growth factor (VEGF) binding to an alpha-type platelet-derived growth factor receptor (PDGFR) on the surface of a cell, and ending with the regulation of a downstream cellular process, e.g. transcription.


embryonic forelimb morphogenesis

description: The process, occurring in the embryo, by which the anatomical structures of the forelimb are generated and organized. The forelimbs are the front limbs of an animal, e.g. the arms of a human.


name: advanced glycation end-product receptor activity

description: Combining with advanced glycation end-products and transmitting the signal to initiate a change in cell activity. Advanced glycation end-products (AGEs) form from a series of chemical reactions after an initial glycation event (a non-enzymatic reaction between reducing sugars and free amino groups of proteins).


iodide peroxidase activity

description: Catalysis of the reaction: iodide + H2O2 = iodine + 2 H2O.


tRNA dimethylallyltransferase activity

description: Catalysis of the reaction: dimethylallyl diphosphate + tRNA = diphosphate + tRNA containing 6-dimethylallyladenosine.


interleukin-21 receptor activity

description: Combining with interleukin-21 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


L-fucose biosynthetic process

description: The chemical reactions and pathways resulting in the formation of L-fucose (6-deoxy-L-galactose).


name: lysine biosynthetic process via diaminopimelate

description: The chemical reactions and pathways resulting in the formation of lysine, via the intermediate diaminopimelate.


name: regulation of execution phase of apoptosis

description: Any process that modulates the frequency, rate or extent of execution phase of apoptosis.


regulation of cholesterol storage

description: Any process that modulates the rate or extent of cholesterol storage. Cholesterol storage is the accumulation and maintenance in cells or tissues of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.


name: luteinizing hormone signaling pathway involved in ovarian follicle development

description: The series of molecular signals initiated by luteinizing hormone binding to a receptor, where the activated receptor signals via downstream effectors that contribute to progression of the ovarian follicle over time, from its formation to the mature structure.


name: fosfomycin 2-glutathione ligase activity

description: Catalysis of the reaction: hydrogen (2R,3S)-3-methyloxiran-2-ylphosphonic acid + glutathione = hydrogen (1R,2R)-1-glutathio-2-hydroxypropylphosphonic acid.


name: regulation of neutrophil apoptotic process

description: Any process that modulates the frequency, rate, or extent of neutrophil apoptotic process.


name: indoleacetic acid ester conjugate biosynthetic process

description: The chemical reactions and pathways resulting in the formation of an indole-3-acetic acid amide conjugate, a form of indoleacetic acid covalently bound to an a sugar or polyol through an ester bond.


alpha-pinene metabolic process

description: The chemical reactions and pathways involving alpha-pinene, a monoterpene that may be a significant factor affecting bacterial activities in nature. It is a major component in tea-tree oils, and gives off a piney smelling odor.


dimethylallylcistransferase activity

description: Catalysis of the reaction: dimethylallyl diphosphate + isopentenyl diphosphate = diphosphate + neryl diphosphate.


name: activation of plasma proteins involved in acute inflammatory response

description: Any process activating plasma proteins by proteolysis as part of an acute inflammatory response.


name: skeletal muscle satellite cell fate specification

description: The process in which a cell becomes capable of differentiating autonomously into a skeletal muscle satellite cell in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed.


guanidinoacetate kinase activity

description: Catalysis of the reaction: ATP + guanidinoacetate = ADP + 2 H+ + phosphoguanidinoacetate.


name: calcium-induced calcium release activity involved in regulation of presynaptic cytosolic calcium ion concentration

description: Any calcium-induced calcium release activity that is involved in regulation of presynaptic cytosolic calcium ion concentration.


name: regulation of insulin-like growth factor receptor signaling pathway

description: Any process that modulates the frequency, rate or extent of insulin-like growth factor receptor signaling.


name: cellular response to prostaglandin I stimulus

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin I stimulus.


dolichol metabolic process

description: The chemical reactions and pathways involving dolichols, any 2,3-dihydropolyprenol derived from four or more linked isoprene units.


name: endocardial cushion to mesenchymal transition involved in heart chamber septation

description: A transition where an endocardial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell that will contribute to the formation of the heart septum.


peptidyl-lysine palmitoylation

description: The palmitoylation of peptidyl-lysine to form peptidyl-N6-palmitoyl-L-lysine.


name: dicarboxylic acid transmembrane transporter activity

description: Enables the transfer of dicarboxylic acids from one side of a membrane to the other. A dicarboxylic acid is an organic acid with two COOH groups.


name: regulation of endodeoxyribonuclease activity

description: Any process that modulates the frequency, rate or extent of endodeoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid by creating internal breaks.


all-trans-neoxanthin metabolic process

description: The chemical reactions and pathways involving all-trans-neoxanthin.


name: cellular response to chondroitin 4'-sulfate

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chondroitin 4'-sulfate stimulus.


behavioral response to ethanol

description: Any process that results in a change in the behavior of an organism as a result of an ethanol stimulus.


regulation of cuticle pigmentation

description: Any process that modulates the frequency, rate or extent of establishment of a pattern of pigment in the cuticle of an organism.


pro-T cell lineage commitment

description: The process in which a lymphoid progenitor cell becomes committed to becoming a pro-T cell.


hypothalamus cell differentiation

description: The differentiation of cells that will contribute to the structure and function of the hypothalamus.


name: regulation of glucomannan catabolic process

description: Any process that modulates the frequency, rate or extent of glucomannan catabolic process.


name: AV node cell-bundle of His cell adhesion involved in cell communication

description: The attachment of an AV node cell to an bundle of His cell via adhesion molecules that results in the cells being juxtaposed so that they can communicate.


5-fluorocytosine deaminase activity

description: Catalysis of the reaction: H+ + flucytosine + H2O = 5-fluorouracil + ammonium.


protein localization to P-body

description: Any process in which a protein is transported to, or maintained at, a P-body.


localization of cell

description: Any process in which a cell is transported to, and/or maintained in, a specific location.


description: The chemical reactions and pathways resulting in the breakdown of 3-(3-hydroxy)phenylpropionate, a hydroxylated derivative of phenylpropionate.


epistomal sclerite morphogenesis

description: The process in which the anatomical structures of the epistomal sclerite are generated and organized.


name: positive regulation of renal amino acid absorption

description: Any process that activates or increases the frequency, rate or extent of renal amino acid absorption.


actin filament bundle convergence

description: A process of actin filament bundle distribution that results in the compaction of actin filaments.


description: Catalysis of the reaction: arachidonate + O2 = (5Z,8Z,10E,12S,14Z)-12-hydroperoxyicosa-5,8,10,14-tetraenoate.


dCDP metabolic process

description: The chemical reactions and pathways involving dCDP, deoxycytidine 5'-diphosphate.


name: post-embryonic camera-type eye development

description: The process occurring during the post-embryonic phase whose specific outcome is the progression of the camera-type eye over time, from its formation to the mature structure.


name: purine nucleotide-sugar transmembrane transporter activity

description: Enables the transfer of a purine nucleotide-sugar from one side of a membrane to the other. Purine nucleotide-sugars are purine nucleotides in glycosidic linkage with a monosaccharide or monosaccharide derivative.


name: CoA-disulfide reductase (NADPH) activity

description: Catalysis of the reaction: 2 CoA + NADP+ = CoA-disulfide + NADPH + H+.


rhombomere 6 formation

description: The process that gives rise to rhombomere 6. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.


vasopressin receptor activity

description: Combining with vasopressin to initiate a change in cell activity.


name: cellular response to isoquinoline alkaloid

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an isoquinoline alkaloid stimulus. An isoquinoline alkaloid is any member of a group of compounds with the heterocyclic ring structure of benzo(c)pyridine which is a structure characteristic of the group of opium alkaloids.


regulation of glucocorticoid secretion

description: Any process that modulates the frequency, rate or extent of glucocorticoid secretion.


negative regulation of protein folding

description: Any process that stops, prevents or reduces the frequency, rate or extent of protein folding.


blastocyst formation

description: The initial formation of a blastocyst from a solid ball of cells known as a morula.


name: negative regulation of osteoclast development

description: Any process that stops, prevents or reduces the frequency, rate or extent of osteoclast development.


name: inositol hexakisphosphate kinase activity

description: Catalysis of the reaction: ATP + 1D-myo-inositol 1,2,3,4,5,6-hexakisphosphate = ADP + diphospho-1D-myo-inositol-pentakisphosphate. The isomeric configuration of diphospho-1D-myo-inositol-pentakisphosphate (PP-IP5) is unknown.


name: galactitol transmembrane transporter activity

description: Enables the transfer of a galactitol from one side of a membrane to the other. Galactitol is the hexitol derived by the reduction of the aldehyde group of either D- or L-galactose.


chloroplast-nucleus signaling pathway

description: The process in which a molecular signal is transduced between the chloroplast and nucleus, such that expression of nuclear encoding photosynthetic proteins is coupled with chloroplast biogenesis.


name: negative regulation of type B pancreatic cell proliferation

description: Any process that stops, prevents or reduces the frequency, rate or extent of type B pancreatic cell proliferation.


cellulose metabolic process

description: The chemical reactions and pathways involving cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation.


structural constituent of myelin sheath

description: The action of a molecule that contributes to the structural integrity of the myelin sheath of a nerve.


name: negative regulation of response to alcohol

description: Any process that stops, prevents or reduces the frequency, rate or extent of response to alcohol.


uracilylalanine synthase activity

description: Catalysis of the reaction: O3-acetyl-L-serine + uracil = 3-(uracil-1-yl)-L-alanine + acetate.


name: positive regulation of adaptive immune effector response

description: Any process that activates or increases the frequency, rate or extent of adaptive immune effector response.


name: negative regulation of platelet-derived growth factor receptor-beta signaling pathway

description: Any process that stops, prevents or reduces the frequency, rate or extent of platelet-derived growth factor receptor-beta signaling pathway.


cellular detoxification of cadmium ion

description: Any process that reduces or removes the toxicity of cadmium cations in a cell. These include transport of cadmium cations away from sensitive areas and to compartments or complexes whose purpose is sequestration.


name: oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with oxygen as acceptor

description: Catalysis of an oxidation-reduction (redox) reaction in which X-H and Y-H form X-Y and the acceptor is oxygen.


GABA-A receptor activity

description: Combining with the amino acid gamma-aminobutyric acid (GABA, 4-aminobutyrate) to initiate a change in cell activity. GABA-A receptors function as chloride channels.


gerfelin catabolic process

description: The chemical reactions and pathways resulting in the breakdown of gerfelin.


cytochrome-c oxidase activity

description: Catalysis of the reaction: 4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.


name: regulation of cell proliferation involved in compound eye morphogenesis

description: Any process that modulates the frequency, rate or extent of cell proliferation involved in compound eye morphogenesis.


description: Catalysis of the reaction: sn-glycerol 3-phosphate + ADP-glucose = 2-O-(beta-D-glucosyl)-sn-glycerol 3-phosphate + ADP + H+.


ABC-type D-allose transporter activity

description: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + D-allose(out) = ADP + phosphate + D-allose(in).


name: establishment of endoplasmic reticulum localization to postsynapse

description: The directed movement of endoplasmic reticulum into a postsynaptic compartment such as a dendritic spine.


ecgonine methyl ester catabolic process

description: The chemical reactions and pathways resulting in the breakdown of ecgonine methyl ester.


'de novo' IMP biosynthetic process

description: The chemical reactions and pathways resulting in the formation of IMP, inosine monophosphate, by the stepwise assembly of a purine ring on ribose 5-phosphate.


name: retrograde trans-synaptic signaling by lipid

description: Cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by a lipid ligand.


peptide amidation

description: The posttranslational conversion of C-terminal glycine-extended peptides to C-terminal alpha-amidated peptides. Occurs to over half of all peptide hormones to give bioactive peptides. This is a two step process catalyzed by a peptidyl-glycine alpha-hydroxylating monooxygenase and a peptidyl-alpha-hydroxyglycine alpha-amidating lyase. In some organisms, this process is catalyzed by two separate enzymes, whereas in higher organisms, one polypeptide catalyzes both reactions.


biofilm matrix assembly

description: A process that results in the assembly of a biofilm matrix.


name: positive regulation of cardiac muscle myoblast proliferation

description: Any process that activates or increases the frequency, rate or extent of cardiac muscle myoblast proliferation.


name: cADPR-sensitive calcium-release channel activity

description: Enables the transmembrane transfer of a calcium ion by a channel that opens when cyclic adenosine diphosphate ribose (cADPR) has been bound by the channel complex or one of its constituent parts.


regulation of defense response to virus

description: Any process that modulates the frequency, rate or extent of the antiviral response of a cell or organism.


description: The binding of a cell to the extracellular matrix via adhesion molecules that do not require the presence of calcium for the interaction.


name: VEGF-activated platelet-derived growth factor receptor signaling pathway

description: The series of molecular signals initiated by vascular endothelial growth factor (VEGF) binding to a platelet-derived growth factor receptor (PDGFR) on the surface of a cell, and ending with the regulation of a downstream cellular process, e.g. transcription.


name: GSI anchor biosynthetic process via N-seryl-glycosylsphingolipidinositolethanolamine

description: The formation of a C-terminal peptidyl-serine ethanolamide-linked glycosylsphingolipidinositol (GSI) anchor following hydrolysis of a seryl-peptide bond in the carboxy-terminal region of a membrane-associated protein.


methylarsonate reductase activity

description: Catalysis of the reaction: 2 glutathione + H+ + methylarsonate = glutathione disulfide + H2O + methylarsonous acid.


multi-species biofilm formation

description: A process in which planktonically growing microorganisms of different species grow at a liquid-air interface or on a solid substrate under the flow of a liquid and produce extracellular polymers that facilitate matrix formation, resulting in a change in the organisms' growth rate and gene transcription.


name: regulation of D-aspartate import across plasma membrane

description: Any process that modulates the frequency, rate or extent of the directed import of D-aspartate from the extracellular region across the plasma membrane and into the cytosol.


cellular response to raffinose

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a raffinose stimulus.


cellular response to L-ascorbic acid

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an L-ascorbic acid (vitamin C) stimulus.


plastid translation

description: The chemical reactions and pathways resulting in the formation of a protein in a plastid. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein; the plastid has its own ribosomes and transfer RNAs, and uses a genetic code that differs from the nuclear code.


thiamine binding

description: Binding to thiamine (vitamin B1), a water soluble vitamin present in fresh vegetables and meats, especially liver.


name: endothelial cell activation involved in immune response

description: A change in the morphology or behavior of an endothelial cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response.


tyrosine catabolic process

description: The chemical reactions and pathways resulting in the breakdown of tyrosine, an aromatic amino acid, 2-amino-3-(4-hydroxyphenyl)propanoic acid.


hard palate development

description: The biological process whose specific outcome is the progression of the hard palate from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. The hard palate is the anterior portion of the palate consisting of bone and mucous membranes.


peptide hormone processing

description: The generation of a mature peptide hormone by posttranslational processing of a prohormone.


dextrin alpha-glucosidase activity

description: Catalysis of the reaction: dextrin + H2O = alpha-D-glucose.


interleukin-27 receptor activity

description: Combining with interleukin-27 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


name: maternal process involved in parturition

description: A reproductive process occurring in the mother that results in birth.


2-octaprenylphenol hydroxylase activity

description: Catalysis of the reaction: 2-octaprenylphenol + NADPH + O2 + H+ = 2-octaprenyl-6-hydroxyphenol + NADP+ + H2O.


brevianamide F biosynthetic process

description: The chemical reactions and pathways resulting in the formation of brevianamide F. Brevianamide F is the biosynthetic precursor of a large family of biologically active prenylated tryptophan-proline 2,5-diketopiperazines that are produced by some fungi.


name: cell wall macromolecule metabolic process

description: The chemical reactions and pathways involving macromolecules forming, or destined to form, part of the cell wall. A cell wall is a rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis.


name: pyruvate dehydrogenase [NAD(P)+] activity

description: Catalysis of the reaction: pyruvate + CoA + NAD(P)+ = acetyl-CoA + CO2 + NAD(P)H.


response to manganese ion

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a manganese ion stimulus.


name: tRNA 4-demethylwyosine alpha-amino-alpha-carboxypropyltransferase activity

description: Catalysis of the reaction: S-adenosyl-L-methionine + 4-demethylwyosine37 in tRNAPhe = 5'-S-methyl-5'-thioadenosine + H+ + 7-[(3S)-3-amino-3-carboxypropyl]-4-demethylwyosine37 in tRNAPhe.


name: regulation of aortic smooth muscle cell differentiation

description: Any process that modulates the frequency, rate or extent of aortic smooth muscle cell differentiation.


response to DDT

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a DDT stimulus. DDT, dichlorodiphenyltrichloroethane, is a chlorinated hydrocarbon pesticide moderately toxic to humans and other animals.


hematopoietic stem cell homeostasis

description: Any biological process involved in the maintenance of the steady-state number of hematopoietic stem cells within a population of cells.


name: negative regulation of male mating behavior

description: Any process that stops, prevents or reduces the frequency, rate or extent of male mating behavior.


name: protein localization to spindle pole body

description: A process in which a protein is transported to, or maintained at, the spindle pole body.


name: positive regulation of mesenchymal stem cell proliferation

description: Any process that activates or increases the frequency, rate or extent of mesenchymal stem cell proliferation.


cytosolic ribosome assembly

description: The aggregation, arrangement and bonding together of the large and small ribosomal subunits into a functional cytosolic ribosome. Distinct stages of this process take place first in the nucleolus, then in the nucleus and finally in the cytosol.


name: regulation of phospholipase C-activating G protein-coupled receptor signaling pathway

description: Any process that modulates the frequency, rate or extent of phospholipase C-activating G protein-coupled receptor signaling pathway.


D-lysine metabolic process

description: The chemical reactions and pathways involving D-lysine, the D-enantiomer of lysine; i.e. (2R)-2,6-diaminohexanoic acid.


stem cell factor receptor activity

description: Combining with stem cell factor (SCF) receptor ligand and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP + a protein-L-tyrosine = ADP + a protein-L-tyrosine phosphate. Stem cell factor is a cytokine that stimulates mast cell growth and differentiation.


name: negative regulation of binding of sperm to zona pellucida

description: Any process that stops, prevents or reduces the frequency, rate or extent of binding of sperm to the zona pellucida.


description: Catalysis of the reaction: 5,6-dihydroxy-3-methyl-2-oxo-1,2-dihydroquinoline + O2 = 3-methyl-5-hydroxy-6-(3-carboxy-3-oxopropenyl)-1H-2-pyridon.


name: cellular response to boron-containing substance levels

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of boron-containing substances.


compound eye development

description: The process whose specific outcome is the progression of the compound eye over time, from its formation to the mature structure. The compound eye is an organ of sight that contains multiple repeating units, often arranged hexagonally. Each unit has its own lens and photoreceptor cell(s) and can generate either a single pixelated image or multiple images, per eye.


name: positive regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway

description: Any process that activates or increases the frequency, rate, or extent of a nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway (NLR) pathway.


name: regulation of endocannabinoid signaling pathway

description: Any process that modulates the frequency, rate or extent of endocannabinoid signaling pathway.


lung smooth muscle development

description: The process whose specific outcome is the progression of smooth muscle in the lung over time, from its formation to the mature structure.


axonemal basal plate assembly

description: The aggregation, arrangement and bonding together of a set of components to form an axonemal basal plate.


glucuronoarabinoxylan catabolic process

description: The chemical reactions and pathways resulting in the breakdown of a glucuronoarabinoxylan.


otolith tethering

description: The attachment of a developing otolith to the kinocilia of tether cells in the inner ear.


regulation of egg-laying behavior

description: Any process that modulates the frequency, rate or extent of the deposition of eggs, either fertilized or not, upon a surface or into a medium.


oncostatin-M-mediated signaling pathway

description: The series of molecular signals initiated by oncostatin-M (OSM) binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. OSM can signal via at least two different receptors (a specific receptor and a LIF receptor) to activate different downstream signal transduction pathways.


name: anthocyanidin 3-O-glucoside 2''-O-glucosyltransferase activity

description: Catalysis of the reaction: UDP-alpha-D-glucose + an anthocyanidin-3-O-beta-D-glucoside = UDP + H+ + an anthocyanidin 3-O-sophoroside.


ethanolamine oxidase activity

description: Catalysis of the reaction: ethanolamine + H2O + O2 = glycolaldehyde + NH3 + H2O2.


name: regulation of histamine secretion by mast cell

description: Any process that modulates the frequency, rate or extent of histamine secretion by mast cell.


name: Spemann organizer formation at the anterior end of the primitive streak

description: Formation of the specialized region at the anterior end of the primitive streak of the embryo that acts as the main signaling center establishing the body plan.


4-nitrotoluene catabolic process

description: The chemical reactions and pathways resulting in the breakdown of 4-nitrotoluene, 1-methyl-4-nitrobenzene.


response to nicotine

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nicotine stimulus.


name: peptidyl-tyrosine dehydrogenation to form (E)-2,3-didehydrotyrosine

description: The oxidation of the C alpha-C beta bond of peptidyl-tyrosine to form peptidyl-(E)-2,3-didehydrotyrosine coupled with cyclization of neighboring residues.


name: histone H2AQ104 methyltransferase activity

description: Catalysis of the reaction: S-adenosyl-L-methionine + (histone H2A)-glutamine (position 104) = S-adenosyl-L-homocysteine + (histone H2A)-N5-methyl-glutamine (position 104). Note that this corresponds to Q105 in yeast.


name: 6-methylsalicylic acid synthase activity

description: Catalysis of the reaction: acetyl-CoA + 3 H+ + 3 malonyl-CoA + NADPH = 6-methylsalicylate + 3 CO2 + 4 CoA + H2O + NADP+.


oogonium development

description: The process that leads to the development of an oogonium, a female gametangium of Oomycetes, containing one or more gametes.


response to 4'-epidoxorubicin

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 4'-epidoxorubicin stimulus.


description: Catalysis of the hydrolysis of the terminal alpha-glucosyl-(1,3)-mannosyl unit from Glc-Man(9)-(GlcNAc)(2) oligosaccharide component of the glycoprotein produced in the Golgi membrane.


phytosteroid catabolic process

description: The chemical reactions and pathways resulting in the breakdown of phytosteroids, steroids that differ from animal steroids in having substitutions at C24 and/or a double bond at C22. Phytosteroids are so named because they occur in higher plants; some, notably ergosterol, are also found in fungi.


cohesin loader activity

description: Facilitating a conformational change to load a cohesin complex around sister chromatids.


bicoid mRNA localization

description: Any process in which bicoid mRNA is transported to and maintained within the oocyte as part of the specification of the anterior/posterior axis.


name: endoplasmic reticulum-organelle membrane tether activity

description: The binding activity of a molecule that brings together two membranes, either via membrane lipid binding or by interacting with a membrane protein, to establish or maintain membrane contact sites and mediate organelle exchange and communication.


description: Catalysis of the reaction: anthranilate + benzoyl-CoA = N-benzoylanthranilate + CoA.


cranial skeletal system development

description: The process whose specific outcome is the progression of a cranial skeletal system over time, from its formation to the mature structure. The cranial skeletal system is the skeletal subdivision of the head, and includes the skull (cranium plus mandible), pharyngeal and/or hyoid apparatus.


name: regulation of establishment of cell polarity

description: Any process that modulates the frequency, rate or extent of establishment of cell polarity.


name: positive regulation of G1 to G0 transition

description: Any process that activates or increases the frequency, rate or extent of G1 to G0 transition.


name: negative regulation of odontogenesis of dentin-containing tooth

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the formation and development of teeth, the hard, bony appendages which are borne on the jaws, or on other bones in the walls of the mouth or pharynx.


name: emindole-SB NADPH:oxygen oxidoreductase (14,15-epoxidizing) activity

description: Catalysis of the reaction: emindole-SB + O2 + NADPH + H+ = 14,15-epoxyemindole-SB + NADP + H2O.


fibronectin fibril organization

description: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a fibronectin fibril.


name: tricaffeoyl spermidine:S-adenosyl-L-methionine O-methyltransferase activity

description: Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the oxygen atom of a tricaffeoyl spermidine molecule.


description: Catalysis of the hydrolysis of the link between N-acetylmuramoyl residues and L-amino acid residues in certain bacterial cell-wall glycopeptides.


SA node cell action potential

description: An action potential that occurs in a sinoatrial node cardiac muscle cell.


nitrate assimilation

description: The nitrogen metabolic process that encompasses the uptake of nitrate from the environment and reduction to ammonia, and results in the incorporation of nitrogen derived from nitrate into cellular substances.


ACG codon-amino acid adaptor activity

description: A triplet codon-amino acid adaptor activity that recognizes an ACG codon.


name: serine-based site-specific recombinase activity

description: Catalysis of the formation of new phosphodiester bonds between a pair of short, unique DNA target sequences; occurs through a phosphoseryl intermediate in which the target sequence is first cleaved by the nucleophilic attack by a serine in the active site.


name: maternal specification of dorsal/ventral axis, oocyte, soma encoded

description: Polarization of the oocyte along the dorsal-ventral axis, by a gene product encoded by somatic cells. An example of this is found in Drosophila melanogaster.


name: positive regulation of pentasaccharide transport

description: Any process that activates or increases the frequency, rate or extent of pentasaccharide transport.


seed trichome maturation

description: A developmental process, independent of morphogenetic (shape) change, that is required for a seed trichome to attain its fully functional state.


cellular response to cGMP

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cGMP (cyclic GMP, guanosine 3',5'-cyclophosphate) stimulus.


name: positive regulation of neural crest formation

description: Any process that increases the rate, frequency, or extent of neural crest formation. Neural crest formation is the formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation proceeds.


name: establishment of cell polarity involved in growth plate cartilage chondrocyte division

description: The cellular process that results in the specification, formation or maintenance of anisotropic intracellular organization that results in the directional division of a growth plate cartilage chondrocyte.


succinate metabolic process

description: The chemical reactions and pathways involving succinate, also known as butanedioate or ethane dicarboxylate, the dianion of succinic acid. Succinate is an important intermediate in metabolism and a component of the TCA cycle.


name: positive regulation of calcium-mediated signaling

description: Any process that activates or increases the frequency, rate or extent of calcium-mediated signaling.


name: establishment of protein-containing complex localization to telomere

description: The directed movement of a protein-containing macromolecular complex to a specific location in the telomeric region of a chromosome.


pre-tubular aggregate formation

description: The cell adhesion process in which mesenchyme cells adhere to one another in the initial stages of the formation of the pre-tubular aggregate, the earliest recognizable structure of the kidney.


name: regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway

description: Any process that modulates the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing 1 (NOD1) pathway.


proximal convoluted tubule development

description: The process whose specific outcome is the progression of the proximal convoluted tubule over time, from its formation to the mature structure. The proximal convoluted tubule is the most proximal portion of the proximal tubule and extends from the glomerular capsule to the proximal straight tubule.


name: pantothenate:sodium symporter activity

description: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: pantothenate(out) + Na+(out) = pantothenate(in) + Na+(in).


medulla oblongata development

description: The process whose specific outcome is the progression of the medulla oblongata over time, from its formation to the mature structure. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate.


response to isooctane

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an isooctane stimulus.


compound eye cone cell differentiation

description: The process in which a relatively unspecialized cell acquires the specialized features of a compound eye cone cell, a cone-shaped cell, that focuses light in a compound eye.


hydroxycinnamoyltransferase activity

description: Catalysis of the transfer of a hydroxycinnamoyl group to an acceptor molecule.


name: glycerol-3-phosphate dehydrogenase (quinone) activity

description: Catalysis of the reaction: sn-glycerol 3-phosphate + a quinone = glycerone phosphate + a quinol.


description: Catalysis of the reaction: phosphoribulosylformimino-AICAR-P + L-glutamine = D-erythro-imidazole-glycerol-phosphate + aminoimidazole carboxamide ribonucleotide + L-glutamate + 2 H+.


aldehyde dehydrogenase (NADP+) activity

description: Catalysis of the reaction: an aldehyde + NADP+ + H2O = an acid + NADPH + H+.


regulation of dermatome development

description: Any process that modulates the rate, frequency, or extent of the progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin.


archaeosine synthase activity

description: Catalysis of the reaction: L-glutamine + 7-cyano-7-carbaguanine15 in tRNA + H2O = L-glutamate + archaeine15 in tRNA.


name: acetyl-CoA biosynthetic process from pyruvate

description: The chemical reactions and pathways resulting in the formation of acetyl-CoA from pyruvate.


name: cell-cell adhesion involved in mesendodermal cell migration

description: The attachment of mesendodermal cells to each other that contributes to the establishment of cell polarity that is part of the directed movement of the cells of the mesendoderm.


name: short-chain fatty acid catabolic process

description: The chemical reactions and pathways resulting in the breakdown of a short-chain fatty acid. A short-chain fatty acid has an aliphatic tail containing fewer than 6 carbons.


name: 5'-adenylyl sulfate transmembrane transporter activity

description: Enables the transfer of 5'-adenylyl sulfate from one side of a membrane to the other.


polycistronic mRNA processing

description: The conversion of a primary mRNA transcript containing more than one complete protein-coding region into individual mature mRNA molecules.


description: Catalysis of the reaction: UDP-alpha-D-glucose + curcumin = curcumin monoglucoside + UDP + H+.


atrial septum development

description: The progression of the atrial septum over time, from its initial formation to the mature structure.


name: negative regulation of cardiac epithelial to mesenchymal transition

description: Any process that stops or decreases the rate, frequency or extent of cardiac epithelial to mesenchymal transition, a transition where a cardiac epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.


name: positive regulation of receptor localization to synapse

description: Any process that activates or increases the frequency, rate or extent of receptor localization to synapse.


name: regulation of heart rate by cardiac conduction

description: A cardiac conduction process that modulates the frequency or rate of heart contraction.


ribosomal small subunit assembly

description: The aggregation, arrangement and bonding together of constituent RNAs and proteins to form the small ribosomal subunit.


regulation of excretion

description: Any process that modulates the frequency, rate, or extent of excretion, the elimination by an organism of the waste products that arise as a result of metabolic activity.


embryonic digit morphogenesis

description: The process, occurring in the embryo, by which the anatomical structures of the digit are generated and organized. A digit is one of the terminal divisions of an appendage, such as a finger or toe.


AMP binding

description: Binding to AMP, adenosine monophosphate.


forebrain astrocyte fate commitment

description: The process in which the developmental fate of a cell becomes restricted such that it will develop into an astrocyte that resides in the forebrain.


name: positive regulation of cumulus cell differentiation

description: Any process that activates or increases the frequency, rate or extent of ovarian cumulus cell differentiation.


ventricular septum morphogenesis

description: The developmental process in which a ventricular septum is generated and organized. A ventricular septum is an anatomical structure that separates the lower chambers (ventricles) of the heart from one another.


name: regulation of ribosomal small subunit export from nucleus

description: Any process that modulates the frequency, rate or extent of ribosomal small subunit export from nucleus.


cellular heat acclimation

description: Any process that increases heat tolerance of a cell in response to high temperatures.


pupation

description: The act of becoming a pupa, a resting stage in the life cycle of organisms with complete metamorphosis. This event marks the end of the prepupal period and the beginning of the pupal period.


description: Catalysis of the reaction: 1-alkyl-sn-glycero-3-phosphocholine + acetyl-CoA = 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine + CoA.


name: symbiont defense to host-produced reactive oxygen species

description: A process in which a symbiont alters or subverts either the host signal transduction pathways leading to the production of reactive oxygen species as part of the host innate immune response.


glyoxylate metabolic process

description: The chemical reactions and pathways involving glyoxylate, the anion of glyoxylic acid, HOC-COOH.


GCG codon-amino acid adaptor activity

description: A triplet codon-amino acid adaptor activity that recognizes a GCG codon.


ferroptosis

description: A programmed cell death characterized morphologically by the presence of smaller than normal mitochondria with condensed mitochondrial membrane densities, reduction or vanishing of mitochondria crista, and outer mitochondrial membrane rupture. Activation of mitochondrial voltage-dependent anion channels and mitogen-activated protein kinases, upregulation of endoplasmic reticulum stress, and inhibition of cystine/glutamate antiporter are involved in the induction of ferroptosis. This process is characterized by the accumulation of lipid peroxidation products and lethal reactive oxygen species (ROS) derived from iron metabolism. Glutathione peroxidase 4 (GPX4), heat shock protein beta-1, and nuclear factor erythroid 2-related factor 2 function as negative regulators of ferroptosis by limiting ROS production and reducing cellular iron uptake, respectively. In contrast, NADPH oxidase and p53 act as positive regulators of ferroptosis by promotion of ROS production and inhibition of expression of SLC7A11 (a specific light-chain subunit of the cystine/glutamate antiporter), respectively. Misregulated ferroptosis has been implicated in multiple physiological and pathological processes.


name: negative regulation of adenylate cyclase-activating glucose-activated G protein-coupled receptor signaling pathway

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the adenylate cyclase-activating glucose-activated G protein-coupled receptor signaling pathway.


name: induction of conjugation with cellular fusion

description: The process in which a cell initiates conjugation with cellular fusion. Conjugation with cellular fusion is the process that results in the union of cellular and genetic information from compatible mating types.


regulation of Malpighian tubule size

description: Ensuring that a Malpighian tubule is the correct length and diameter.


positive regulation of ovulation

description: Any process that activates or increases the frequency, rate or extent of ovulation, the release of a mature ovum/oocyte from an ovary.


alpha-glucan metabolic process

description: The chemical reactions and pathways involving alpha-glucans, compounds composed of glucose residues linked by alpha-D-glucosidic bonds.


response to docetaxel trihydrate

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a docetaxel trihydrate stimulus.


name: negative regulation of monocyte activation

description: Any process that stops, prevents or reduces the frequency, rate or extent of monocyte activation.


description: Catalysis of the reaction: UDP-alpha-D-glucose + N(6)-dimethylallyladenine = H+ + 7-(alpha-D-glucosyl)-N(6)-isopentenyladenine + UDP.


name: symbiont-mediated evasion of recognition by host innate immune effector

description: A process by which a symbiont mitigates the effects of recognition by a host innate immune effector. Effectors have a direct activity against a symbiont and include complement, antimicrobial peptides, and bacterial restriction enzymes. The host is defined as the larger of the organisms involved in a symbiotic interaction.


name: translocation of molecules into symbiont

description: The directed movement of molecule(s) produced by an organism to a location inside the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.


description: Catalysis of the reaction: acyl-CoA + 2-acylglycerol = CoA + diacylglycerol.


phosphatidylcholine floppase activity

description: Catalysis of the movement of phosphatidylcholine from the cytosolic to the exoplasmic leaftlet of a membrane, using energy from the hydrolysis of ATP.


Z-phenylacetaldoxime catabolic process

description: The chemical reactions and pathways resulting in the breakdown of Z-phenylacetaldoxime, a member of the glucosinolate group of compounds.


metanephric podocyte development

description: The process whose specific outcome is the progression of a metanephric glomerular visceral epithelial cell over time, from its formation to the mature structure. A metanephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the metanephros.


Group I intron splicing

description: The splicing of Group I introns. This occurs by a ribozymic mechanism where the intron sequence forms a distinct 3D structure, characteristic of Group I introns and involved in determining the locations of the splice sites (there do not appear to be consensus splice site sequences) as well as having a role in catalyzing the splicing reactions, though protein factors are also required in vivo. Splicing occurs by a series of two transesterification reactions, generally with exogenous guanosine as the initiating nucleophile. The intron is excised as a linear piece (though it may subsequently circularize).


globoside biosynthetic process

description: The chemical reactions and pathways resulting in the formation of a ceramide with a core structure of GalNAc-beta-(1->3)-Gal-alpha-(1->4)-Glc(I).


name: ATPase-coupled urea transmembrane transporter activity

description: Catalysis of the reaction: ATP + H2O + urea(out) = ADP + phosphate + urea(in).


FAT10 activating enzyme activity

description: Catalysis of the activation of the small ubiquitin-related modifier FAT10, through the formation of an ATP-dependent high-energy thiolester bond.


alkaloid biosynthetic process

description: The chemical reactions and pathways resulting in the formation of alkaloids, nitrogen-containing natural products which are not otherwise classified as nonprotein amino acids, amines, peptides, amines, cyanogenic glycosides, glucosinolates, cofactors, phytohormones, or primary metabolite (such as purine or pyrimidine bases).


ribonuclease R activity

description: Catalysis of the reaction: RNA + H2O = 5'-phosphomononucleotides. Cleaves RNA in the 3' to 5' direction, leaving an undigested core of 3-5 nucleotides.


name: 4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate biosynthetic process

description: The chemical reactions and pathways resulting in the formation of 4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate, a precursor of 4-amino-4-deoxy-L-arabinose (L-Ara4N).


leaf proximal/distal pattern formation

description: The regionalization process within a leaf by which specific areas of cell differentiation are determined along a proximal/distal axis.


description: Catalysis of the reaction: cobalt-precorrin 3 + S-adenosyl-L-methionine = cobalt-precorrin 4 + S-adenosyl-L-homocysteine.


alliin lyase activity

description: Catalysis of the reaction: an S-alkyl-L-cysteine S-oxide = an alkyl sulfenate + 2-aminoacrylate.


name: acyl-lipid omega-(9-4) desaturase activity

description: Catalysis of the reaction: a (9Z,12Z)-octadecadienoyl-containing glycerolipid + 2 Fe(II)-[cytochrome b5] + 2 H+ + O2 = a (5Z,9Z,12Z)-octadecatrienoyl-containing glycerolipid + 2 Fe(III)-[cytochrome b5] + 2 H2O. Can also use a substrate with 3 double bonds (a (9Z,12Z,15Z)-octadecatrienoyl-containing glycerolipid) and add a fourth double bond (a (5Z,9Z,12Z,15Z)-octadecatetraenoyl-containing glycerolipid).


oomycete sporangium development

description: The process that leads to the development of an oomycete sporangium, a single-celled or many-celled structure that germinates directly to form an infection hypha or differentiates, through specialized cleavage vesicles, into between 10 and 30 zoospores, which are laterally flagellated.


biofilm matrix disassembly

description: A process that results in the disassembly of a biofilm matrix.


name: very-low-density lipoprotein particle receptor activity

description: Combining with a very-low-density lipoprotein particle and delivering the very-low-density lipoprotein into the cell via endocytosis.


description: Catalysis of the reaction: phenylacetyl-CoA + isopenicillin N + H2O = CoA + penicillin G + L-2-aminohexanedioate.


response to herbivore

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a herbivore.


name: poly(ribitol phosphate) teichoic acid biosynthetic process

description: The chemical reactions and pathways resulting in the formation of poly(ribitol phosphate) teichoic acid.


description: Catalysis of the reaction: ATP + aminoglycoside = ADP + phosphoaminoglycoside.


L-histidine biosynthetic process

description: The chemical reactions and pathways resulting in the formation of L-histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid.


seedling development

description: The process whose specific outcome is the progression of the seedling over time, beginning with seed germination and ending when the first adult leaves emerge.


name: glomerular parietal epithelial cell development

description: The process whose specific outcome is the progression of a glomerular parietal epithelial cell over time, from its formation to the mature structure. Glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport.


name: vibrational conductance of sound to the inner ear

description: The transmission of vibrations via ossicles to the inner ear.


description: Catalysis of the reaction: L-methionine + 2-oxoglutarate = 4-methylthio-2-oxobutyrate + L-glutamate.


name: tripeptide transmembrane transporter activity

description: Enables the transfer of a tripeptide, a compound containing three amino acids linked together by peptide bonds, from one side of a membrane to the other.


alpha-galactosidase activity

description: Catalysis of the hydrolysis of terminal, non-reducing alpha-D-galactose residues in alpha-D-galactosides, including galactose oligosaccharides, galactomannans and galactolipids.


granulosa cell fate commitment

description: The cell fate commitment of precursor cells that will become granulosa cells.


name: glutathione disulfide oxidoreductase activity

description: Catalysis of the reaction: 2 glutathione + electron acceptor = glutathione disulfide + electron donor.


name: NAD+-histone H3S10 serine ADP-ribosyltransferase activity

description: Catalysis of the transfer of ADP-ribose groups to the serine-10 or an equivalent residue of the N-terminal tail of histone H3.


heart valve morphogenesis

description: The process in which the structure of a heart valve is generated and organized.


name: positive regulation of compound eye pigmentation

description: Any process that activates or increases the frequency, rate or extent of establishment of a pattern of pigment in the compound eye.


Meynert cell differentiation

description: The process in which a relatively unspecialized cell acquires the specialized features of a Meynert cell.


description: Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + lysosomal-enzyme D-mannose = UMP + lysosomal-enzyme N-acetyl-D-glucosaminyl-phospho-D-mannose.


inferior olivary nucleus development

description: The process whose specific outcome is the progression of the inferior olivary nucleus over time, from its formation to the mature structure. The inferior olivary nucleus is a capsule-shaped structure in the ventral medulla located just lateral and dorsal to the medullary pyramids. Neurons in the inferior olivary nucleus are the source of climbing fiber input to the cerebellar cortex; these neurons have been implicated in various functions, such as learning and timing of movements.


dUDP catabolic process

description: The chemical reactions and pathways resulting in the breakdown of dUDP, deoxyuridine (5'-)diphosphate.


sweet taste receptor activity

description: Combining with soluble sweet compounds to initiate a change in cell activity. These receptors are responsible for the sense of sweet taste.


negative regulation of eclosion

description: Any process that stops, prevents, or reduces the frequency, rate or extent of eclosion.


description: Catalysis of the reaction: 4-aminobutanoate + 2-oxoglutarate = succinate semialdehyde + L-glutamate.


tRNA-dihydrouridine20 synthase activity

description: Catalysis of the reaction: a 5,6-dihydrouracil20 in tRNA + NAD(P) = H+ + a uracil20 in tRNA + NAD(P)H.


name: epithelial cell proliferation involved in prostatic bud elongation

description: The multiplication of epithelial cells, contributing to the expansion of the primary prostatic bud.


name: regulation of hair follicle placode formation

description: Any process that modulates the rate, frequency, or extent of hair follicle placode formation, the developmental process in which a hair placode forms. An hair follicle placode is a thickening of the ectoderm that will give rise to the hair follicle bud.


regulation of cell fate determination

description: Any process that modulates the frequency, rate or extent of cell fate determination.


intracellular phosphate ion homeostasis

description: A homeostatic process involved in the maintenance of a steady state level of phosphate ions within a cell.


name: negative regulation of mitochondrial membrane permeability involved in apoptotic process

description: Any negative regulation of mitochondrial membrane permeability that is involved in apoptotic process.


name: GTP:coenzyme F420 guanyltransferase activity

description: Catalysis of the reaction: GTP + factor gamma-F420-2 + H+ = coenzyme F390-G + diphosphate.


description: Catalysis of the reaction: 5-aminomethyl-2-thiouridine34 in tRNA + S-adenosyl-L-methionine = 5-methylaminomethyl-2-thiouridine34 in tRNA + H+ + S-adenosyl-L-homocysteine. This enzyme specifically adds the terminal methyl group of 5-[(methylamino)methyl]-2-thiouridylate.


styrene dioxygenase activity

description: Catalysis of the reaction: styrene + O2 + NADH + H+ = NAD+ + styrene cis-glycol.


muscle organ morphogenesis

description: The process in which the anatomical structures of muscle are generated and organized.


name: negative regulation of transport across blood-brain barrier

description: Any process that stops, prevents or reduces the frequency, rate or extent of transport across blood-brain barrier.


description: Catalysis of the reaction: 3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione + O2 = 3-hydroxy-5,9,17-trioxo-4,5:9,10-disecoandrosta-1(10),2-dien-4-oate + H+.


putrescine oxidase activity

description: Catalysis of the reaction: putrescine + O2 + H2O = 4-aminobutanal + NH3 + H2O2.


description: Catalysis of the reaction: vanillate + L-glutamate(1-) + ATP = H+ + N-vanillate-L-glutamate + AMP + diphosphoric acid.


name: negative regulation of SMAD protein signal transduction

description: Any process that decreases the rate, frequency or extent of the SMAD protein signaling pathway.


flight involved in flight behavior

description: Self-propelled movement of an organism from one location to another through the air that is part of the organism's response to external or internal stimuli resulting in flight.


name: negative regulation of response to pullulan

description: Any process that stops, prevents or reduces the frequency, rate or extent of response to pullulan.


description: Catalysis of the reaction: amino acyl-[protein] + NAD+ = H+ + (ADP-D-ribosyl)-amino acyl-[protein] + nicotinamide.


nitrobenzoate nitroreductase activity

description: Catalysis of the reaction: o-nitrobenzoate + NADPH + H+ = o-hydroxylaminobenzoate + NADP+.


name: transport of virus in host, tissue to tissue

description: The transport of a virus between tissues in a multicellular organism.


name: regulation of cellular response to X-ray

description: Any process that modulates the frequency, rate or extent of cellular response to X-ray.


name: regulation of plant-type hypersensitive response

description: Any endogenous process that modulates the frequency, rate or extent of the plant hypersensitive response.