name: regulation of actin cortical patch localization

description: Any process that modulates the localization of an actin cortical patch. An actin cortical patch is a discrete actin-containing structure found just beneath the plasma membrane in fungal cells.


category: biolink:MolecularActivity biolink:Occurrent biolink:OntologyClass biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: Catalysis of the reaction: hydroxidodioxidosulfidosulfate + a reduced thioredoxin = sulfite + hydrogen sulfide + H+ + an oxidized thioredoxin.


name: vesicle targeting, plasma membrane to endosome

category: biolink:BiologicalProcess biolink:Occurrent biolink:OntologyClass biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: The process in which vesicles formed at the plasma membrane are directed to specific destinations in endosome membranes, mediated by molecules at the vesicle membrane and target membrane surfaces.


leucyl-tRNA aminoacylation

description: The process of coupling leucine to leucyl-tRNA, catalyzed by leucyl-tRNA synthetase. The leucyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2'-OH group of a leucine-accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification.


hexitol catabolic process

description: The chemical reactions and pathways resulting in the breakdown of hexitols, any alditol with a chain of six carbon atoms in the molecule.


description: Catalysis of the reaction: CoA + substrate-serine = adenosine 3',5'-bisphosphate + substrate-serine-4'-phosphopantetheine. The transfer of the 4'-phosphopantetheine (Ppant) co-factor from coenzyme A to the hydroxyl side chain of the serine residue of acyl- or peptidyl-carrier protein (ACP or PCP) to convert them from the apo to the holo form.


serine 2-dehydrogenase activity

description: Catalysis of the reaction: L-serine + H2O + NAD+ = 3-hydroxypyruvate + NH3 + NADH.


leaf development

description: The process whose specific outcome is the progression of the leaf over time, from its formation to the mature structure.


name: negative regulation of cellular response to testosterone stimulus

description: Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to testosterone stimulus.


peroxisome membrane biogenesis

description: The process in which a peroxisome membrane is synthesized, aggregates, and bonds together.


RNA polymerase I promoter clearance

description: A process that mediates the transition from the initiation to the elongation phases of transcription by RNA polymerase I, generally including a conformational change from the initiation conformation to the elongation conformation. Promoter clearance often involves breaking contact with transcription factors involved only in the initiation phase and making contacts with elongation specific factors.


mitochondrial tRNA 5'-end processing

description: The process in which the 5' end of a pre-tRNA molecule is converted to that of a mature tRNA in the mitochondrion.


name: peptide cross-linking via 2-(S-L-cysteinyl)-D-allo-threonine

description: The post-translational cross-linking of a cysteine residue to an L-threonine residue to form 2-(S-L-cysteinyl)-D-allo-threonine.


neurotrophin receptor activity

description: Combining with a neurotrophin, any of a family of growth factors that prevent apoptosis in neurons and promote nerve growth, and transmitting the signal to initiate a change in cell activity.


name: regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling

description: Any process that modulates the rate, frequency, or extent of branching involved in salivary gland morphogenesis as a result of signals being generated by the mesenchyme and received and interpreted by the salivary gland epithelium.


name: negative regulation of cellular response to nitrogen starvation

description: Any process that stops, prevents, or reduces the frequency, rate or extent of a cellular response to nitrogen starvation.


name: regulation of phytoalexin metabolic process

description: Any process that modulates the frequency, rate or extent of phytoalexin metabolism, the chemical reactions and pathways involving phytoalexins, any of a range of substances produced by plants as part of their defense response.


name: site-specific endodeoxyribonuclease activity, specific for altered base

description: Catalysis of the hydrolysis of ester linkages at specific sites within a deoxyribonucleic acid molecule by creating internal breaks.


name: hydrolase activity, acting on acid sulfur-sulfur bonds

description: Catalysis of the hydrolysis of any acid sulfur-sulfur bond.


name: negative regulation of amine metabolic process

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving amines.


gastric mucosal blood circulation

description: The flow of blood through the gastric mucosa of an animal, enabling the transport of nutrients and the removal of waste products.


proteasome regulatory particle binding

description: Binding to a proteasome regulatory particle.


name: negative regulation of blood circulation

description: Any process that stops, prevents or reduces the frequency, rate or extent of blood circulation.


basement membrane disassembly

description: The controlled breakdown of the basement membrane in the context of a normal process such as imaginal disc eversion.


macrolide 2'-kinase activity

description: Catalysis of the reaction: ATP + oleandomycin = ADP + 2 H+ + oleandomycin 2'-O-phosphate.


description: Catalysis of the reaction: H2O + maltose 6'-phosphate = D-glucose + D-glucose 6-phosphate.


2-aminohexanoate transaminase activity

description: Catalysis of the reaction: L-2-aminohexanoate + 2-oxoglutarate = 2-oxohexanoate + L-glutamate.


malate dehydrogenase activity

description: Catalysis of the reversible conversion of pyruvate or oxaloacetate to malate.


name: 23S rRNA (guanine(748)-N(1))-methyltransferase activity

description: Catalysis of the reaction: S-adenosyl-L-methionine + guanine(748) in 23S rRNA = N(1)-methylguanine(748) in 23S rRNA + S-adenosyl-L-homocysteine.


isoleucine biosynthetic process

description: The chemical reactions and pathways resulting in the formation of isoleucine, (2R*,3R*)-2-amino-3-methylpentanoic acid.


SMAD protein signal transduction

category: biolink:Pathway biolink:OntologyClass biolink:BiologicalProcess biolink:Occurrent biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: An intracellular signaling cassette that starts with the activation of a SMAD protein, leading to the formation of a complex with co-SMADs, which translocates to the nucleus and regulates transcription of specific target genes.


description: Catalysis of the reaction: UDP-alpha-D-glucose + 8-methylthiooctylhydroximate = H+ + 7-methylthioheptyldesulfoglucosinolate + UDP.


rhythmic synaptic transmission

description: Any process involved in the generation of rhythmic, synchronous synaptic inputs in a neural circuit.


GCU codon-amino acid adaptor activity

description: A triplet codon-amino acid adaptor activity that recognizes a GCU codon.


ecdysone binding

description: Binding to 20-hydroxyecdysone (ecdysone). Ecdysone is an ecdysteroid produced by the prothoracic glands of immature insects and the ovaries of adult females, which stimulates growth and molting.


pyruvate catabolic process

description: The chemical reactions and pathways resulting in the breakdown of pyruvate, 2-oxopropanoate.


2-alkyn-1-ol dehydrogenase activity

description: Catalysis of the reaction: 2-butyne-1,4-diol + NAD+ = 4-hydroxy-2-butynal + H+ + NADH.


name: positive regulation of pancreatic A cell differentiation

description: Any process that activates or increases the frequency, rate or extent of pancreatic A cell differentiation.


leukotriene D4 metabolic process

description: The chemical reactions and pathways involving leukotriene D4.


IgA receptor activity

description: Combining with an immunoglobulin of an IgA isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


type IV pilus-dependent motility

description: Any process involved in the controlled movement of a bacterial cell which is dependent on the presence of type IV pili. Includes social gliding motility and twitching motility.


2-oxobutyrate catabolic process

description: The chemical reactions and pathways resulting in the breakdown of 2-oxobutyrate, the anion of the organic acid 2-oxobutyric acid, which contains a ketone group on carbon 2.


uracil metabolic process

description: The chemical reactions and pathways involving uracil, 2,4-dioxopyrimidine, one of the pyrimidine bases occurring in RNA, but not in DNA.


alternative respiration

description: Alternative respiration pathway consumes oxygen, oxidizes NADH to NAD+ and generates water. During electron flow, proton motive force is diminished resulting in fewer molecules of ATP compared to cytochrome pathway. The pathway is found in plants, algae and some protozoa.


name: cell proliferation involved in outflow tract morphogenesis

description: The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to the shaping of the outflow tract.


cellular response to triterpenoid

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a triterpenoid stimulus.


name: germarium-derived female germ-line cyst encapsulation

description: Formation of a single follicular epithelium around the germ-line derived cells of a cyst formed in the germarium. An example of this process is found in Drosophila melanogaster.


detection of pheromone

description: The series of events in which a pheromone stimulus is received by a cell and converted into a molecular signal.


bixin aldehyde dehydrogenase activity

description: Catalysis of the reaction: bixin aldehyde + O2 + NAD = norbixin + NADH + H+.


name: positive regulation of heart rate by circulating epinephrine

description: The process in which the secretion of epinephrine into the bloodstream increases the rate of heart muscle contraction.


name: negative regulation of sorocarp spore cell differentiation

description: Any process that stops, prevents or reduces the frequency, rate or extent of sorocarp spore cell differentiation.


name: D-lactate dehydrogenase (quinone) activity

description: Catalysis of the reaction: (R)-lactate + an ubiquinone = pyruvate + an ubiquinol.


description: Catalysis of the reaction: a cytidine in mRNA + S-adenosyl-L-methionine = a 5-methylcytidine in mRNA + H+ + S-adenosyl-L-homocysteine.


Cdc42 protein signal transduction

description: An intracellular signaling cassette in which a small monomeric GTPase of the Cdc42 subfamily relays a signal.


name: intermediate-density lipoprotein particle binding

description: Binding to a intermediate-density lipoprotein particle, a triglyceride-rich lipoprotein particle that typically contains APOB100, APOE and APOCs and has a density of 1.006-1.019 g/ml and a diameter of between 25-30 nm.


polyphosphate biosynthetic process

description: The chemical reactions and pathways resulting in the formation of a polyphosphate, the anion or salt of polyphosphoric acid.


cytidylate cyclase activity

description: Catalysis of the reaction: CTP = 3',5'-cyclic CMP + diphosphate + H+.


4-nitrophenol 2-monooxygenase activity

description: Catalysis of the reaction: 4-nitrophenol + H+ + NADH + O2 = 4-nitrocatechol + H2O + NAD+.


name: negative regulation of appressorium formation

description: Any process that stops, prevents, or reduces the frequency, rate or extent of symbiont appressorium formation.


regulation of ectoderm development

description: Any process that modulates the frequency, rate or extent of ectoderm development.


arabinan metabolic process

description: The chemical reactions and pathways involving arabinan, a polysaccharide composed of arabinose residues.


RITS complex localization

description: Any process in which a RITS complex is transported to, or maintained in, a specific location.


name: protein localization to polar microtubule

description: A process in which a protein is transported to, or maintained in, a location within a polar microtubule.


blood vessel maturation

description: A developmental process, independent of morphogenetic (shape) change, that is required for a blood vessel to attain its fully functional state.


name: stomach pylorus smooth muscle contraction

description: A process in which force is generated within gastric smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the most distal part of the stomach.


name: histone H2AK119 ubiquitin ligase activity

description: Catalysis of the transfer of a ubiquitin molecule to histone 2A at the lysine-119 residue.


response to fluid shear stress

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fluid shear stress stimulus. Fluid shear stress is the force acting on an object in a system where the fluid is moving across a solid surface.


name: trans-synaptic signaling by carbon monoxide

description: Cell-cell signaling between presynapse and postsynapse mediated by carbon monoxide.


isopentenyl phosphate kinase activity

description: Catalysis of the reaction: isopentenyl phosphate(2-) + ATP(4-) = isopentenyl diphosphate(3-) + ADP(3-).


XMP biosynthetic process

description: The chemical reactions and pathways resulting in the formation of XMP, xanthosine monophosphate.


progression of neural tube closure

description: The process in which the neural folds are fused extending from the initial closure points.


amylin receptor activity

description: Combining with amylin to initiate a change in cell activity.


name: dolichyl diphosphate biosynthetic process

description: The chemical reactions and pathways resulting in the formation of dolichyl diphosphate, a diphosphorylated dolichol derivative.


terminal region determination

description: Specification of the terminal regions (the two non-segmented ends) of the embryo by the gap genes; exemplified in insects by the actions of huckebein and tailless gene products.


name: regulation of secondary cell wall biogenesis

description: Any process that modulates the frequency, rate or extent of secondary cell wall biogenesis.


collenchyma cell differentiation

description: The process in which a relatively unspecialized cell acquires specialized features of a collenchyma cell. This is a plant cell in which the primary cell walls are unevenly thickened, with most thickening occurring at the cell corners. Cells are living and able to grow, they are elongated, and lignin and secondary walls absent. Collenchyma cells make up collenchyma tissue which acts as a supporting tissue in growing shoots, leaves and petioles. This tissue is often arranged in cortical ribs, as seen prominently in celery and rhubarb petioles.


interleukin-7 production

description: The appearance of interleukin-7 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


beta 2 integrin biosynthetic process

description: The chemical reactions and pathways resulting in the formation of beta 2 integrins, a subfamily of integrins which contain the beta 2 subunit.


name: positive regulation of hematopoietic stem cell migration

description: Any process that activates or increases the frequency, rate or extent of hematopoietic stem cell migration.


name: regulation of bundle of His cell action potential

description: Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a cardiac muscle cell of the bundle of His. This typically occurs via modulation of the activity or expression of voltage-gated ion channels.


name: regulation of lipid transport across blood-brain barrier

description: Any process that modulates the frequency, rate or extent of lipid transport across blood-brain barrier.


deoxycytidine biosynthetic process

description: The chemical reactions and pathways resulting in the formation of deoxycytidine, 2-deoxyribosylcytosine, one of the four major nucleosides of DNA.


name: tRNA transcription by RNA polymerase III

description: The synthesis of transfer RNA (tRNA) from a DNA template by RNA polymerase III (Pol III), originating at a Pol III promoter.


name: regulation of calcium-independent cell-cell adhesion

description: Any process that modulates the frequency, rate or extent of the attachment of one cell to another cell via adhesion molecules that do not require the presence of calcium for the interaction.


regulation of blood vessel branching

description: Any process that modulates the frequency, rate or extent of blood vessel branching.


description: Catalysis of the reaction: acetyl-CoA + an N-hydroxyarylamine = CoA + an N-acetoxyarylamine.


ribitol metabolic process

description: The chemical reactions and pathways involving ribitol, a pentitol derived formally by reduction of the -CHO group of either D- or L-ribose. It occurs free in some plants and is a component of riboflavin.


description: Catalysis of the reaction: beta-carotene + O2 = 10'-apo-beta-carotenal + beta-ionone.


description: Catalysis of the reaction: 5-deoxy-D-glucuronate = 5-dehydro-2-deoxy-D-gluconate.


lysine racemase activity

description: Catalysis of the reaction: L-lysine = D-lysine.


name: apical constriction involved in ventral furrow formation

description: The actin-mediated process that results in contraction of the apical end of a polarized columnar epithelial cell, contributing to formation of a ventral indentation (furrow) from the blastoderm epithelium, which is internalized to form a tube in the interior of the embryo, marking the start of gastrulation.


11-oxo-beta-amyrin 30-oxidase activity

description: Catalysis of the reaction: 11-oxo-beta-amyrin + 3 NADPH + 3 O2 + 2 H+ = glycyrrhetinic acid + 3 NADP + 4 H2O.


name: epicardium-derived cell migration to the myocardium

description: The orderly movement of a cell that have undergone an epithelial to mesenchymal transition from the epicardium into the myocardium.


snoRNA localization

description: Any process in which small nucleolar RNA is transported to, or maintained in, a specific location.


5-dehydro-2-deoxygluconokinase activity

description: Catalysis of the reaction: ATP + 5-dehydro-2-deoxy-D-gluconate = ADP + 6-phospho-5-dehydro-2-deoxy-D-gluconate.


name: putrescine biosynthetic process from arginine, using agmatinase

description: The chemical reactions and pathways resulting in the formation of putrescine, 1,4-diaminobutane, from other compounds, including arginine; in this pathway, arginine is converted to agmatine, and agmatine is converted to putrescine in a single enzymatic step.


description: The chemical reactions and pathways resulting in the breakdown of beta-D-galactofuranose.


name: mesonephric interstitial fibroblast fate commitment

description: The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesonephric interstitial fibroblast.


neural crest cell fate specification

description: The process in which a cell becomes capable of differentiating autonomously into a neural crest cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.


name: positive regulation of nitrogen utilization

description: Any process that activates or increases the frequency, rate or extent of nitrogen utilization.


name: positive regulation of endodermal cell differentiation

description: Any process that activates or increases the frequency, rate or extent of endodermal cell differentiation.


name: positive regulation of austinol biosynthetic process

description: Any process that activates or increases the frequency, rate or extent of austinol biosynthetic process.


glutamate synthase (NADH) activity

description: Catalysis of the reaction: 2 L-glutamate + NAD+ = 2-oxoglutarate + L-glutamine + H+ + NADH.


name: tetrapyrrole biosynthetic process from glutamate

description: The chemical reactions and pathways leading to the formation of tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next, from other compounds, including L-glutamate.


name: planar cell polarity pathway involved in cardiac muscle cell fate commitment

description: The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via effectors other than beta-catenin and contributing to a cardioblast being committed to a cardiac muscle cell fate.


description: Catalysis of the hydrolysis of (1->6)-alpha-D-glucosidic linkages in dextrans, to remove successive isomaltotriose units from the non-reducing ends of the chains.


name: thioacetamide S-oxide S-oxygenase activity

description: Catalysis of the reaction: thioacetamide S-oxide + O2 + 2 H+ + 2 e- = thioacetamide S,S-dioxide + H2O.


R2/R5 cell differentiation

description: The process in which relatively unspecialized cells acquire the specialized features of R2 and R5 photoreceptors. An example of this process is found in Drosophila melanogaster.


apiose 1-reductase activity

description: Catalysis of the reaction: D-apiitol + NAD+ = D-apiose + H+ + NADH.


name: maturation of LSU-rRNA from tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, 2S rRNA, LSU-rRNA)

description: Any process involved in the maturation of a precursor Large SubUnit (LSU) ribosomal RNA (rRNA) molecule into a mature LSU-rRNA molecule from the pre-rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, 5.8 S rRNA, 2S rRNA, and Large Subunit (LSU) in that order from 5' to 3' along the primary transcript.


metal chelating activity

description: The formation of bonds from two or more atoms within the same ligand to a metal atom in complexes in which the metal is part of a ring.


name: regulation of systemic arterial blood pressure by renin-angiotensin

description: The process in which renin-angiotensin modulates the force with which blood passes through the circulatory system.


regulation of mesoderm development

description: Any process that modulates the frequency, rate or extent of mesoderm development.


aspartate-tRNA ligase activity

description: Catalysis of the reaction: ATP + L-aspartate + tRNA(Asp) = AMP + diphosphate + L-aspartyl-tRNA(Asp).


phosphatidylserine transfer activity

description: Removes phosphatidylserine from the outer leaflet of a donor membrane, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to the outer leaflet of an acceptor membrane.


peptide histaminyltransferase activity

description: Catalysis of the reaction: histamine + L-glutaminyl-[protein] = 5-histaminyl-L-glutamyl-[protein].


name: positive regulation of antigen receptor-mediated signaling pathway

description: Any process that activates or increases the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B- or T cell.


beta-ketoadipate pathway

description: A pathway of aromatic compound degradation by ortho-cleavage; one branch converts protocatechuate, derived from phenolic compounds, to beta-ketoadipate, and the other branch converts catechol, generated from various aromatic hydrocarbons, amino aromatics, and lignin monomers, also to beta-ketoadipate. Two additional steps accomplish the conversion of beta-ketoadipate to tricarboxylic acid cycle intermediates.


phosphatidylserine floppase activity

description: Catalysis of the movement of phosphatidylserine from the cytosolic to the exoplasmic leaftlet of a membrane, using energy from the hydrolysis of ATP.


name: symbiont-mediated activation of host G protein-coupled receptor signal transduction

description: A process in which a symbiont initiates, promotes, or enhances a G protein-coupled receptor signal transduction pathway in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.


tyrocidine metabolic process

description: The chemical reactions and pathways involving tyrocidine.


thromboxane receptor activity

description: Combining with a thromboxane (TXA) to initiate a change in cell activity.


name: histidine catabolic process to hydantoin-5-propionate

description: The chemical reactions and pathways resulting in the breakdown of histidine into other compounds, including hydantoin-5-propionate.


name: negative regulation of cytokine-mediated signaling pathway

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the cytokine mediated signaling pathway.


description: The chemical reactions and pathways resulting in the formation of beta-1,2-linked oligomannosides, which are found in fungal cell wall phosphopeptidomannan and phospholipomannan.


foregut morphogenesis

description: The process in which the anatomical structures of the foregut are generated and organized.


name: pyridoxine transmembrane transporter activity

description: Enables the transfer of pyridoxine from one side of a membrane to the other. Pyridoxine, 2-methyl-3-hydroxy-4,5-bis(hydroxymethyl)pyridine, is one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate.


channel-forming ionophore activity

description: Enables transport of a solute across a membrane. This kind of transporter interacts much more weakly with the solute than the carrier does. It is an aqueous pore that extends across the membrane. It may change from closed to open and back. It transports faster than a carrier. It is always passive.


response to silicon dioxide

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a silicon dioxide stimulus.


name: indole-containing compound metabolic process

description: The chemical reactions and pathways involving compounds that contain an indole (2,3-benzopyrrole) skeleton.


description: Catalysis of the reaction: 4'-hydroxyacetophenone + H+ + NADPH + O2 = 4-hydroxyphenyl acetate + H2O + NADP+.


pineal gland development

description: The progression of the pineal gland over time from its initial formation until its mature state. The pineal gland is an endocrine gland that secretes melatonin and is involved in circadian rhythms.


structural constituent of virion

description: The action of a molecule that contributes to the structural integrity of a virion.


gastrulation with mouth forming second

description: A gastrulation process in which the initial invagination becomes the anus and the mouth forms second.


galactitol metabolic process

description: The chemical reactions and pathways involving galactitol, the hexitol derived by the reduction of the aldehyde group of either D- or L-galactose.


description: Catalysis of the reaction: rhamnetin + S-adenosyl-L-methionine = ombuin + S-adenosyl-L-homocysteine + H+.


name: L-lysine catabolic process to glutarate, by acetylation

description: The chemical reactions and pathways resulting in the breakdown of L-lysine into other compounds, including glutarate, by acetylation.


(S)-canadine synthase activity

description: Catalysis of the reaction: (S)-tetrahydrocolumbamine + [reduced NADPH--hemoprotein reductase] + O2 -> (S)-canadine + [oxidized NADPH--hemoprotein reductase] + 2 H2O.


description: Catalysis of the reaction: A [sulfatase]-L-cysteine + O2 + 2 a thiol = a [sulfatase]-3-oxo-L-alanine + hydrogen sulfide + a disulfide + H2O.


name: regulation of deoxyribonuclease activity

description: Any process that modulates the frequency, rate or extent of deoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid.


photoreactive repair

description: The repair of UV-induced T-T, C-T and C-C dimers by directly reversing the damage to restore the original pyrimidines.


description: The chemical reactions and pathways resulting in the formation of dehydro-D-arabinono-1,4-lactone, the gamma-lactone (5R)-3,4-dihydroxy-5-(hydroxymethyl)furan-2(5H)-one.


name: positive regulation of relaxation of cardiac muscle

description: Any process that activates or increases the frequency, rate or extent of relaxation of cardiac muscle.


actinorhodin biosynthetic process

description: The chemical reactions and pathways resulting in the formation of actinorhodin.


phosphoribulokinase activity

description: Catalysis of the reaction: D-ribulose 5-phosphate + ATP = D-ribulose 1,5-bisphosphate + ADP + 2 H+.


phosphatidic acid biosynthetic process

description: The chemical reactions and pathways resulting in the formation of phosphatidic acid, any derivative of glycerol phosphate in which both the remaining hydroxyl groups of the glycerol moiety are esterified with fatty acids.


name: malate transmembrane transporter activity

description: Enables the transfer of malate from one side of a membrane to the other. Malate is a chiral hydroxydicarboxylic acid, hydroxybutanedioic acid. The (+) enantiomer is an important intermediate in metabolism as a component of both the TCA cycle and the glyoxylate cycle.


description: Catalysis of the reaction: S-methyl-L-methionine + L-homocysteine = 2 L-methionine + H+.


name: regulation of cleistothecium development

description: Any process that modulates the frequency, rate or extent of cleistothecium development, a process that leads to the formation of a cleistothecium. The cleistothecium is a closed sexual fruiting body that contains ascospores in linear asci, characteristic of some filamentous Ascomycete fungi such as members of the genera Aspergillus and Emericella.


CAAX-box protein modification

description: The covalent alteration of one or more amino acid residues within the CAAX box region of CAAX box proteins.


name: genital disc anterior/posterior pattern formation

description: The establishment, maintenance and elaboration of the anterior/posterior axis of the genital disc. An anterior and posterior compartment form in each of the three genital disc primoridia (the female genital disc primordium, the male genital disc primordium and the anal primordium).


epithelial cell migration

description: The orderly movement of an epithelial cell from one site to another, often during the development of a multicellular organism.


bone maturation

description: A developmental process, independent of morphogenetic (shape) change, that is required for bone to attain its fully functional state.


name: skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration

description: Any process by which the number of skeletal muscle satellite cells in a skeletal muscle is maintained during muscle regeneration. There are at least three mechanisms by which this is achieved. Skeletal muscle satellite stem cell asymmetric division ensures satellite stem cell numbers are kept constant. Symmetric division of these cells amplifies the number of skeletal muscle satellite stem cells. Some adult skeletal muscle myoblasts (descendants of activated satellite cells) can develop back into quiescent satellite cells, replenishing the overall pool of satellite cells.


tensidol B metabolic process

description: The chemical reactions and pathways involving tensidol B.


name: regulation of retrograde trans-synaptic signaling by trans-synaptic protein complex

description: Any process that modulates the frequency, rate or extent of retrograde trans-synaptic signaling by a trans-synaptic complex.


name: anterior mRNA localization involved in anterior/posterior axis specification

description: Any process in which a mRNA is transported to, and maintained in the anterior portion of the oocyte and/or syncytial embryo contributing to the specification of the anterior/posterior axis.


lobar bronchus epithelium development

description: The biological process whose specific outcome is the progression of a lobar bronchus epithelium from an initial condition to its mature state. This process begins with the formation of the lobar bronchus epithelium and ends with the mature structure. The lobar bronchus epithelium is the tissue made up of epithelial cells that lines the inside of the lobar bronchus.


aerotaxis

description: The directed movement of a motile cell or organism in response to environmental oxygen.


name: antigen processing and presentation of endogenous peptide antigen via MHC class Ib

description: The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class Ib protein complex. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family.


name: lignostilbene alpha beta-dioxygenase activity

description: Catalysis of the reaction: 1,2-bis(4-hydroxy-3-methoxyphenyl)ethylene + O2 = 2 vanillin.


digestive system process

description: A physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism.


name: alcohol dehydrogenase (cytochrome c(L)) activity

description: Catalysis of the reaction: 2 [Fe(III)cytochrome cL] + a primary alcohol = 2 [Fe(II)cytochrome cL] + an aldehyde + 2 H+.


name: regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell

description: Any process that modulates the frequency, rate or extent of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell.


name: regulation of methanofuran metabolic process

description: Any process that modulates the frequency, rate or extent of methanofuran metabolic process.


name: 1,5-anhydro-D-fructose reductase (1,5-anhydro-D-mannitol-forming) activity

description: Catalysis of the reaction: 1,5-anhydro-D-mannitol + NADP+ = 1,5-anhydro-D-fructose + H+ + NADPH.


nose morphogenesis

description: The process in which the anatomical structures of the nose are generated and organized. The nose is the specialized structure of the face that serves as the organ of the sense of smell and as part of the respiratory system. Includes the nasi externus (external nose) and cavitas nasi (nasal cavity).


name: hydroxymate-containing siderophore biosynthetic process

description: The chemical reactions and pathways resulting in the formation of a siderophore from other compounds, including hydroxamic acid. Hydroxamate is one of the three major chemical groups incorporated into siderophore structures with catechol and a-hydroxycarboxylate, each having a high selectivity for iron(3+).


name: positive regulation of compound eye photoreceptor development

description: Any process that activates or increases the frequency, rate or extent of compound eye photoreceptor development.


anthocyanidin reductase activity

description: Catalysis of the reaction: a flavan-3-ol + 2 NAD(P)+ = an anthocyanidin + 2 NAD(P)H + H+.


dTTP catabolic process

description: The chemical reactions and pathways resulting in the breakdown of dTTP, deoxyribosylthymine triphosphate.


name: cyclic pyranopterin monophosphate synthase activity

description: Catalysis of the reaction: (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate = cyclic pyranopterin phosphate + diphosphate.


sesquiterpenoid metabolic process

description: The chemical reactions and pathways involving sesquiterpenoid compounds, terpenoids with three isoprene units.


cytokinin dehydrogenase activity

description: Catalysis of the reaction: N6-dimethylallyladenine + acceptor + H2O = adenine + 3-methylbut-2-enal + reduced electron acceptor.


penicillin amidase activity

description: Catalysis of the reaction: penicillin + H2O = a carboxylate + 6-aminopenicillanate.


snoRNP binding

description: Binding to a small nucleolar ribonucleoprotein particle.


name: positive regulation of T cell differentiation

description: Any process that activates or increases the frequency, rate or extent of T cell differentiation.


chrysobactin metabolic process

description: The chemical reactions and pathways involving the siderophore chrysobactin (alpha-N-(2,3-dihydroxybenzoyl)-D-lysyl-L-serine).


name: macrophage colony-stimulating factor signaling pathway

description: The series of molecular signals initiated by the binding of the cytokine macrophage colony-stimulating factor (M-CSF) to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.


name: regulation of induction of conjugation upon nitrogen starvation

description: Any process that modulates the frequency of induction of conjugation upon nitrogen starvation, the process in which a cell initiates conjugation with cellular fusion upon nitrogen starvation.


mesonephric nephron tubule formation

description: The developmental process pertaining to the initial formation of a mesonephric nephron tubule from unspecified parts. A mesonephric nephron tubule is an epithelial tube that is part of a nephron in the mesonephros.


name: protein-RNA covalent cross-linking repair

description: A process that rescues stalled ribosomes by removing the covalent cross-link between RNA and a protein.


skeletal muscle fiber adaptation

description: Any process in which the skeletal muscle fibers change their phenotypic profiles in response to altered functional demands and a variety of signals. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast.


name: regulation of viral entry into host cell

description: Any process that modulates the frequency, rate or extent of the viral entry into the host cell.


name: negative regulation of heart rate in another organism

description: Any process that stops, prevents or reduces the frequency of heart contraction of another organism.


name: virus-mediated perturbation of host defense response

description: A process in which a virus interferes with the ability of the host to mount a defense in response to its presence. Host defenses may be induced by the presence of the virus or may be preformed (e.g. physical barriers). The host is defined as the larger of the organisms involved in a symbiotic interaction.


establishment of tissue polarity

description: Coordinated organization of groups of cells in a tissue, such that they all orient to similar coordinates.


catecholamine catabolic process

description: The chemical reactions and pathways resulting in the breakdown of any of a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine.


regulation of rRNA catabolic process

description: Any process that modulates the frequency, rate or extent of rRNA catabolic process.


name: regulation of poly(3-hydroxyalkanoate) biosynthetic process

description: Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of poly(3-hydroxyalkanoates), polyesters of 3-hydroxyacids produced as intracellular granules by a large variety of bacteria.


ent-kaurene oxidation to kaurenoic acid

description: The three successive oxidations of the 4-methyl group of ent-kaurene to form ent-kaur-16-en-19-oate, kaurenoic acid. This process may be carried out entirely by the enzyme ent-kaurene oxidase.


name: positive regulation of lymphocyte anergy

description: Any process that activates or increases the frequency, rate, or extent of lymphocyte anergy.


name: methanopterin-containing compound biosynthetic process

description: The chemical reactions and pathways resulting in the formation of a methanopterin.


name: formate dehydrogenase (coenzyme F420) activity

description: Catalysis of the reaction: formate + coenzyme F420 = CO2 + reduced coenzyme F420.


name: 1-18:1-2-16:0-phosphatidylglycerol omega-6 desaturase activity

description: Catalysis of the reaction: 1-[(9Z)-octadec-9-enoyl]-2-hexadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol)(1-) + O2 + a reduced electron acceptor = 1-18:2-2-16:0-phosphatidylglycerol + 2 H2O + an oxidized electron acceptor.


name: regulation of postsynaptic cytosolic calcium ion concentration

description: Any process that regulates the concentration of calcium in the postsynaptic cytosol.


name: growth hormone receptor signaling pathway

description: The series of molecular signals generated as a consequence of growth hormone receptor binding to its physiological ligand.


description: Catalysis of the reaction: monomethylamine + a monomethylamine corrinoid protein = a methylated monomethylamine corrinoid protein + NH3.


negative regulation of fear response

description: Any process that stops, prevents or reduces the frequency, rate or extent of fear response.


name: formation of stylet for nutrient acquisition

description: The assembly of a stylet, a hollow protrusible spear-like symbiont structure projected into the host cell for the purpose of obtaining nutrients. The host is defined as the larger of the organisms involved in a symbiotic interaction.


mandelamide amidase activity

description: Catalysis of the reaction: (R)-mandelamide + H2O = (R)-mandelate + NH4.


name: immune response-regulating cell surface receptor signaling pathway involved in phagocytosis

description: An immune response-regulating cell surface receptor signaling pathway that contributes to the endocytic engulfment of external particulate material by phagocytes.


shamixanthone metabolic process

description: The chemical reactions and pathways involving shamixanthone.


muscle cell proliferation

description: The expansion of a muscle cell population by cell division.


alpha-sialidase activity

description: Catalysis of the hydrolysis of alpha-glycosidic linkages in oligo- or poly(sialic) acids.


name: symbiont-mediated perturbation of host salicylic acid-mediated signal transduction pathway

description: A process in which a symbiont alters or subverts a salicylic acid-mediated signal transduction pathway in its host. The host is defined as the larger of the organisms involved in a symbiotic interaction.


name: positive regulation of nematode pharynx morphogenesis

description: Any process that activates or increases the frequency, rate or extent of nematode pharynx morphogenesis.


name: high-affinity copper ion transmembrane transporter activity

description: Enables the transfer of a copper ions (Cu2+) from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.


ventriculo bulbo valve formation

description: The developmental process pertaining to the initial formation of the ventriculo bulbo valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable.


CDP-choline pathway

description: The phosphatidylcholine biosynthetic process that begins with the phosphorylation of choline and ends with the combination of CDP-choline with diacylglycerol to form phosphatidylcholine.


name: gonadotropin-releasing hormone receptor activity

description: Combining with gonadotropin-releasing hormone to initiate a change in cell activity. Gonadotropin-releasing hormone (GnRH) is a peptide hormone responsible for the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the anterior pituitary. GnRH is synthesized and released by the hypothalamus.


dorsal spinal cord development

description: The process whose specific outcome is the progression of the dorsal region of the spinal cord over time, from its formation to the mature structure. The dorsal region of the mature spinal cord contains neurons that process and relay sensory input.


description: Catalysis of the reaction: (R)-2-hydroxyglutaryl-CoA = H2O + glutaconyl-CoA.


name: dihydroorotate dehydrogenase (NAD+) activity

description: Catalysis of the reaction: (S)-dihydroorotate + NAD+ = H+ + NADH + orotate.


name: symbiont-mediated disruption of host cellular anatomical entity

description: The process in which an organism effects a change that impairs the structure or function of a host cellular anatomical entity. The host is defined as the larger of the organisms involved in a symbiotic interaction.


name: pyridoxal transmembrane transporter activity

description: Enables the transfer of pyridoxal from one side of a membrane to the other. Pyridoxal, 3-hydroxy-5-(hydroxymethyl)-2-methyl-4-pyridinecarboxaldehyde, is one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate.


IMP dehydrogenase activity

description: Catalysis of the reaction: inosine 5'-phosphate + NAD+ + H2O = xanthosine 5'-phosphate + NADH + H+.


name: negative regulation of mesenchymal cell apoptotic process involved in metanephros development

description: Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal cell apoptotic process involved in metanephros development.


glycosome organization

description: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a glycosome, a membrane-bounded organelle found in organisms from the order Kinetoplastida that houses the enzymes of glycolysis.


4-alpha-glucanotransferase activity

description: Catalysis of the transfer of a segment of a (1->4)-alpha-D-glucan to a new 4-position in an acceptor, which may be glucose or (1->4)-alpha-D-glucan.


neutrophil mediated immunity

description: Any process involved in the carrying out of an immune response by a neutrophil.


name: symbiont-mediated suppression of host JAK-STAT cascade via inhibition of STAT activity

description: A process in which a symbiont interferes with, inhibits or disrupt a JAK-STAT signal cascade in the host organism by reducing the activity of host STAT (signal transducer and activator of transcription). STATs are SH2 domain-containing proteins which lie downstream of many signaling receptors. Upon phosphorylation by JAKs, STAT proteins hetero- or homo-dimerize and translocate to the nucleus to activate transcription of target genes.


description: Catalysis of the reaction: indole-3-acetate + L-glutamate + ATP = H+ + indole-3-acetyl-glutamate + AMP + diphosphoric acid.


name: RNA NAD-cap (NMN-forming) hydrolase activity

description: Catalysis of the reaction: a 5'-end NAD+-phospho-ribonucleoside in mRNA + H2O = a 5'-end phospho-adenosine-phospho-ribonucleoside in mRNA + beta-nicotinamide D-ribonucleotide + 2 H+.


trichloroethylene metabolic process

description: The chemical reactions and pathways involving trichloroethylene, a toxic, colorless, photoreactive, chlorinated hydrocarbon liquid, commonly used as a metal degreaser and solvent.


name: regulation of epithelial to mesenchymal transition involved in endocardial cushion formation

description: Any process that modulates the frequency, rate or extent of epithelial to mesenchymal transition involved in endocardial cushion formation.


anal fin morphogenesis

description: The process in which the anatomical structures of the anal fin are generated and organized. An anal fin is an unpaired medial fin on the ventral aspect near the caudal end of a fish, which provides lateral stability while swimming.


name: negative regulation of cilium-dependent cell motility

description: Any process that stops, prevents or reduces the frequency, rate or extent of cilium-dependent cell motility.


interleukin-9 production

description: The appearance of interleukin-9 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


protein destabilization

description: Any process that decreases the stability of a protein, making it more vulnerable to degradative processes or aggregation.


name: regulation of neural precursor cell proliferation

description: Any process that modulates the frequency, rate or extent of neural precursor cell proliferation.


pseurotin A metabolic process

description: The chemical reactions and pathways involving pseurotin A.


name: baroreceptor detection of increased arterial stretch

description: The series of events by which an increase in diameter of an artery is detected and converted to a molecular signal.


name: regulation of smooth muscle cell apoptotic process

description: Any process that modulates the frequency, rate, or extent of smooth muscle cell apoptotic process.


name: cell adhesion involved in retrograde extension

description: The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix that contributes to the process of retrograde extension.


pyridoxal 4-dehydrogenase activity

description: Catalysis of the reaction: NAD+ + pyridoxal = 4-pyridoxolactone + H+ + NADH.


ethanolamine kinase activity

description: Catalysis of the reaction: ATP + ethanolamine = ADP + 2 H+ + phosphoethanolamine.


urea channel activity

description: Enables the energy-independent facilitated diffusion of urea through a transmembrane aqueous pore or channel.


progesterone receptor signaling pathway

description: A nuclear receptor-mediated signaling pathway initiated by a progesterone binding to an intracellular receptor of the nuclear receptor protein family, and ending with regulation of a downstream cellular process, e.g. transcription.


response to ecdysone

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ecdysone stimulus.


name: nuclear polyadenylation-dependent CUT catabolic process

description: The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of a cryptic unstable transcript (CUT), initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target CUT.


name: regulation of nerve growth factor receptor activity

description: Any process that modulates the frequency, rate or extent of the activity of the nerve growth factor (NGF) receptor.


regulation of protein refolding

description: Any process that regulates the rate, frequency, or extent of protein refolding. Protein refolding is the process carried out by a cell that restores the biological activity of an unfolded or misfolded protein, using helper proteins such as chaperones.


description: Catalysis of the reaction: 4-acetamidobutanoate + H2O = acetate + 4-aminobutanoate.


name: neural crest cell differentiation involved in thymus development

description: Any neural crest cell differentiation that is involved in thymus development.


tRNA pseudouridine synthesis

description: The intramolecular conversion of uridine to pseudouridine in a tRNA molecule.


pyruvate decarboxylase activity

description: Catalysis of the reaction: a 2-oxo acid = an aldehyde + CO2.


name: regulation of cholesterol transporter activity

description: Any process that modulates the rate, frequency, or extent of cholesterol transporter activity.


microvillus organization

description: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a microvillus, a thin cylindrical membrane-covered projection on the surface of a cell.


maintenance of dormancy

description: The dormancy process that results in an organism remaining in dormancy. Dormancy (sometimes called a dormant state) is a suspension of most physiological activity and growth that can be reactivated.


chromoplast organization

description: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the chromoplast. A chromoplast is a plastid containing pigments other than chlorophyll, usually yellow and orange carotenoid pigments.


chorionic trophoblast cell development

description: The process whose specific outcome is the progression of the chorionic trophoblast over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.


name: modulation by symbiont of host heat acclimation

description: Any process in which an organism modulates the host's tolerance to high temperatures, above the optimal temperature for that organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.


name: specification of segmental identity, mandibular segment

description: The specification of the characteristic structures of the mandibular segment following establishment of segment boundaries. Identity is considered to be the aggregate of characteristics by which a structure is recognized.


name: CTP:geranylgeraniol kinase activity

description: Catalysis of the reaction: geranylgeraniol + CTP = all-trans-geranyl-geranyl monophosphate + CDP.


deoxyinosine salvage

description: Any process that generates deoxyinosine from derivatives of it, without de novo synthesis.


name: valine N-monooxygenase (oxime forming) activity

description: Catalysis of the reaction: L-valine + 2 O2 + 2 NADPH(4-) + 2 H+ = (E)-2-methylpropanal oxime + 2 NADP(3-) + carbon dioxide + 3 H2O.


diacylglycerol catabolic process

description: The chemical reactions and pathways resulting in the breakdown of diacylglycerol, a glyceride in which any two of the R groups (positions not specified) are acyl groups while the remaining R group can be either H or an alkyl group.


name: symbiont-mediated suppression of host adaptive immune response

description: A process by which a symbiont inhibits or disrupts the normal execution of the adaptive immune response of the host organism, an immune response based on directed amplification of specific receptors for antigen produced through a somatic diversification process, and allowing for enhanced response to subsequent exposures to the same antigen (immunological memory).


name: crossover junction DNA endonuclease activity

description: Catalysis of the endonucleolytic cleavage at a junction such as a reciprocal single-stranded crossover between two homologous DNA duplexes (Holliday junction).


valine biosynthetic process

description: The chemical reactions and pathways resulting in the formation of valine, 2-amino-3-methylbutanoic acid.


glial cell proliferation

description: The multiplication or reproduction of glial cells by cell division, resulting in the expansion of their population. Glial cells exist throughout the nervous system, and include Schwann cells, astrocytes, and oligodendrocytes among others.


name: negative regulation of granuloma formation

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of granuloma formation.


name: nascent polypeptide-associated complex binding

description: Binding to nascent polypeptide-associated complex, a heterodimeric protein complex that can reversibly bind to ribosomes and is located in direct proximity to newly synthesized polypeptide chains as they emerge from the ribosome.


name: positive regulation of synaptic plasticity by chemical substance

description: The process in which a chemical substance increases synaptic plasticity, the ability of synapses to change as circumstances require.


name: positive regulation of iron ion transport

description: Any process that activates or increases the frequency, rate or extent of the directed movement of iron ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


name: regulation of arugosin biosynthetic process

description: Any process that modulates the frequency, rate or extent of arugosin biosynthetic process.


name: regulation of biological process involved in symbiotic interaction

description: Any process that modulates the frequency, rate or extent of symbiosis, an interaction between two organisms living together in more or less intimate association.


imaginal disc pattern formation

description: The regionalization process that results in defined areas of the imaginal disc that will undergo specific cell differentaiton. Imaginal discs are epithelial infoldings in the larvae of holometabolous insects that develop into adult appendages (legs, antennae, wings, etc.) during metamorphosis from larval to adult form.


actin ubiquitination

description: The modification of actin by addition of ubiquitin groups.


thelarche

description: The beginning of development of the breasts in the female.


brain renin-angiotensin system

description: The process in which an angiotensin-mediated signaling system present in the brain regulates the force with which blood passes through the circulatory system.


name: 9,10 (9', 10')-carotenoid-cleaving dioxygenase activity

description: Catalysis of the oxidative cleavage of carotenoids at the (9, 10) and/or (9', 10') double bond.


myristoyltransferase activity

description: Catalysis of the transfer of a myristoyl (CH3-[CH2]12-CO-) group to an acceptor molecule.


pollen intine formation

description: Formation of pollen intine, the inner layer of the pollen wall. The reticulate pollen wall pattern consists of two layers, exine and intine.


negative regulation of viral life cycle

description: Any process that stops, prevents or reduces the frequency, rate or extent of viral life cycle.


name: negative regulation of proteinase activated receptor activity

description: Any process that stops, prevents or reduces the frequency, rate or extent of proteinase activated receptor activity.


description: Catalysis of the reaction: N(2)-(2-carboxyethyl)-L-arginine + ATP = AMP + deoxyamidinoproclavaminate + diphosphate + 2 H+.


name: myotube cell development involved in skeletal muscle regeneration

description: The process aimed at the progression of a myotube cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. This occurs as part of the process of skeletal muscle regeneration. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse.


hindgut development

description: The process whose specific outcome is the progression of the hindgut over time, from its formation to the mature structure. The hindgut is part of the alimentary canal that lies posterior to the midgut.


granulosa cell proliferation

description: The multiplication or reproduction of granulosa cells, resulting in the expansion of the granulosa cells population. A granulosa cell is a supporting cell for the developing female gamete in the ovary of mammals. They develop from the coelomic epithelial cells of the gonadal ridge.


description: Catalysis of the reaction: CMP-N-acetyl-beta-neuraminate + 2 Fe(II)-[cytochrome b5] + 2 H+ + O2 = CMP-N-glycoloyl-beta-neuraminate + 2 Fe(III)-[cytochrome b5] + H2O.


name: negative regulation of paraxial mesodermal cell fate specification

description: Any process that stops, prevents, or reduces the frequency, rate or extent of paraxial mesoderm cell fate specification.


glucuronoarabinoxylan metabolic process

description: The chemical reactions and pathways involving xylan, a polymer containing a beta-(1->4)-linked D-xylose backbone decorated with glucuronic acid and arabinose side units.


name: calcium-induced calcium release activity involved in regulation of postsynaptic cytosolic calcium ion concentration

description: Any calcium-induced calcium release activity that is involved in regulation of postsynaptic cytosolic calcium ion concentration.


response to 5-fluorouracil

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 5-fluorouracil stimulus.


name: negative regulation of cardiac muscle cell contraction

description: Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle cell contraction.


name: negative regulation of cartilage development

description: Any process that decreases the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate.


appendage segmentation

description: Division of an appendage, an organ or part that is attached to the main body of an organism, into a series of semi-repetitive parts or segments. Most arthropod appendages, such as the legs and antennae, are visibly segmented.


name: polyol transmembrane transporter activity

description: Enables the transfer of a polyol from one side of a membrane to the other. A polyol is any polyhydric alcohol.


name: peptide mating pheromone maturation involved in regulation of pheromone-induced unidirectional conjugation

description: The formation of a mature peptide mating pheromone by proteolysis and/or modification of a peptide precursor, occurring in the context of pheromone-induced unidirectional conjugation.


N-acetylgalactosamine binding

description: Binding to N-acetylgalactosamine, 2-acetamido-2-deoxygalactopyranose, the n-acetyl derivative of galactosamine.


kynurenine metabolic process

description: The chemical reactions and pathways involving kynurenine, the amino acid 3-(2-aminobenzoyl)-alanine.


protein decanoylation

description: The modification of a protein amino acid by formation of an ester or amide with decanoic acid.


sphingomyelin synthase activity

description: Catalysis of the reaction: 1,2-diacyl-sn-glycero-3-phosphocholine + ceramide = 1,2-diacyl-sn-glycerol + sphingomyelin.


name: negative regulation of cellular response to X-ray

description: Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to X-ray.


name: guanosine pentaphosphate biosynthetic process

description: The chemical reactions and pathways resulting in the formation of guanine pentaphosphate (5'-pppGpp-3'), a derivative of guanine riboside with five phosphates.


cellular response to azide

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an azide stimulus.


octanol metabolic process

description: The chemical reactions and pathways involving octanol, the 8-carbon alcohol with the formula C8H17OH.


name: negative regulation of melanin biosynthetic process

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of melanin.


mannogen metabolic process

description: The chemical reactions and pathways involving mannogen, a mannose-containing polysaccharide that is a major energy reserve in Leishmania.


ammonium ion metabolic process

description: The chemical reactions and pathways involving the ammonium ion.


neuropilin signaling pathway

description: The series of molecular signals initiated by an extracellular ligand binding to a neuropilin protein on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.


Purkinje myocyte action potential

description: An action potential that occurs in a Purkinje myocyte.


description: Binding to an oligosaccharyltransferase complex.


name: iron-sulfur-molybdenum cofactor biosynthetic process

description: The chemical reactions and pathways resulting in the formation of iron-sulfur-molybdenum cofactor.


glucosinolate biosynthetic process

description: The chemical reactions and pathways resulting in the formation of glucosinolates, substituted thioglucosides found in rapeseed products and related cruciferae.


bidentate ribonuclease III activity

description: Catalysis of the digestion of double-stranded RNAs into 20 to 30-nucleotide products. These products typically associate to the RNA-induced silencing complex and serve as guide RNAs for posttranslational RNA interference.


lipid III floppase activity

description: Enables the transbilayer of capsular-polysaccharides (Und-PP-GlcNAc-ManNAcA-Fuc4NAc (lipid III)) from the inner to the outer leaflet of the cytoplasmic membrane during the assembly of ECA. Capsular polysaccharides make up the capsule, a protective structure surrounding some species of bacteria and fungi.


D-xylulose reductase activity

description: Catalysis of the reaction: NAD+ + xylitol = D-xylulose + H+ + NADH.


head morphogenesis

description: The process in which the anatomical structures of the head are generated and organized. The head is the anterior-most division of the body.


orthodenticle mRNA localization

description: Any process in which orthodenticle mRNA is transported to and maintained in the oocyte and/or syncytial embryo as part of the process that will specify the anterior/posterior axis.


name: tricyclic triterpenoid metabolic process

description: The chemical reactions and pathways involving tricyclic triterpenoid compounds, terpenoids with six isoprene units and 3 rings.


candicidin metabolic process

description: The chemical reactions and pathways involving candicidin.


description: Catalysis of the reaction: N(2)-benzoyl-D-arginine-4-nitroanilide + H2O = 4-nitroaniline + N(2)-benzoyl-D-arginine + H+.


citrate-CoA ligase activity

description: Catalysis of the reaction: ATP + citrate + CoA = (3S)-citryl-CoA + ADP + H+ + phosphate.


name: epithelial cell type specification, open tracheal system

description: Allocation of epithelial cells within each migrating branch in an open tracheal system to distinct tracheal cell fates. During the migration phase each branch forms a well-defined number of cell types (including fusion cells, terminal cells and branch cells) at precise positions.


mesonephric podocyte development

description: The process whose specific outcome is the progression of a mesonephric glomerular visceral epithelial cell over time, from its formation to the mature structure. A mesonephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the mesonephros.


mucilage extrusion from seed coat

description: The process in which seed mucilage expands through hydration and breaks the outer cell wall that encapsulates the whole seed upon imbibition. Mucilage, mainly composed of pectins, is formed during seed development and deposited into the apoplast underneath the outer wall of the seed coat.


arsenite methyltransferase activity

description: Catalysis of the reaction: S-adenosyl-L-methionine + arsenite = S-adenosyl-L-homocysteine + methylarsonate.


name: negative regulation of ARF protein signal transduction

description: Any process that stops, prevents, or reduces the frequency, rate or extent of ARF protein signal transduction.


N-cyclopropylmelamine metabolic process

description: The chemical reactions and pathways involving N-cyclopropylmelamine, a triazine compound commonly used as an insect growth regulator insecticide.


pole plasm protein localization

description: Any process in which a protein is transported to, or maintained in, the oocyte pole plasm. An example of this is found in Drosophila melanogaster.


tricellular tight junction assembly

description: The aggregation, arrangement and bonding together of a set of components to form a tricellular tight junction.


description: Catalysis of the reaction: ATP(4-) + H2O + a cis-keto-C60-meroacyl-[acp] = diphosphoric acid + a cis-keto-meroacyl-adenylate + a holo-[acyl-carrier protein].


name: cell-cell adhesion involved in cerebral cortex tangential migration using cell-cell interactions

description: The attachment of cells to one another to form groups of cells involved in cerebral cortex tangential migration.


name: negative regulation of growth factor dependent skeletal muscle satellite cell proliferation

description: Any process that stops, prevents or reduces the frequency, rate or extent of satellite cell proliferation; dependent on specific growth factor activity such as fibroblast growth factors and transforming growth factor beta.


regulation of kidney size

description: Any process that modulates the size of a kidney.


response to psychosocial stress

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of exposure to aversive or demanding psychological and social conditions that tax or exceed the behavioral resources of the organism.


phenylalanine-tRNA ligase activity

description: Catalysis of the reaction: ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + L-phenylalanyl-tRNA(Phe).


diphthine-ammonia ligase activity

description: Catalysis of the reaction: ATP + diphthine + NH4 = ADP + diphthamide + H+ + phosphate.


name: positive regulation of amoeboid sperm motility

description: Any process that activates or increases the frequency, rate or extent of amoeboid sperm motility.


description: Catalysis of the reaction: L-ribulose 5-phosphate = L-xylulose 5-phosphate.


determination of bilateral symmetry

description: The establishment of an organism's body plan or part of an organism with respect to a single longitudinal plane. The pattern can either be symmetric, such that the halves are mirror images, or asymmetric where the pattern deviates from this symmetry.


name: regulation of apoptotic process in bone marrow cell

description: Any process that modulates the occurrence or rate of cell death by apoptotic process in the bone marrow.


description: Catalysis of the dimethylation of two adjacent adenine residues in a rRNA, using S-adenosyl-L-methionine as a methyl donor.


name: epithelial cell differentiation involved in mammary gland alveolus development

description: The process in which a relatively unspecialized epithelial cell becomes a more specialized epithelial cell of the mammary gland alveolus.


mesonephric glomerulus development

description: The progression of the mesonephric glomerulus over time from its initial formation until its mature state. The mesonephric glomerulus is a capillary tuft which forms a close network with the visceral epithelium (podocytes) and the mesangium to form the filtration barrier and is surrounded by Bowman's capsule in nephrons of the mature vertebrate kidney, or mesonephros.


carboxymethylhydantoinase activity

description: Catalysis of the reaction: L-5-carboxymethylhydantoin + H2O = N-carbamoyl-L-aspartate + H+.


name: assembly of large subunit precursor of preribosome

description: The aggregation, arrangement and bonding together of a set of components to form the large subunit precursor of the preribosome.


enucleate erythrocyte development

description: The process aimed at the progression of an enucleate erythrocyte over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.


eye blink reflex

description: The reflex process in which a mechanical stimulus applied to the eye elicits a response of the eyelid closing.


glycerol ether biosynthetic process

description: The chemical reactions and pathways resulting in the formation of glycerol ethers, any anhydride formed between two organic hydroxy compounds, one of which is glycerol.


name: starch utilization system complex assembly

description: The aggregation, arrangement and bonding together of the starch utilization system complex, a complex of cell envelope-associated proteins that degrades glycan.


sodium ion binding

description: Binding to a sodium ion (Na+).


description: Catalysis of the reaction: 5'-acylphosphoadenosine + H2O = AMP + a carboxylate.


hydrotropism

description: Growth or movement in a sessile organism toward or away from water, as of the roots of a plant.


negative regulation of odontogenesis

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the formation and development of a tooth or teeth.


name: transcription elongation by RNA polymerase III

description: The extension of an RNA molecule after transcription initiation and promoter clearance at an RNA polymerase III promoter by the addition of ribonucleotides catalyzed by RNA polymerase III.


DNA-templated transcription termination

description: The completion of transcription: the RNA polymerase pauses, the RNA-DNA hybrid dissociates, followed by the release of the RNA polymerase from its DNA template.


defasciculation of motor neuron axon

description: Separation of a motor axon away from a bundle of axons known as a fascicle.


description: Catalysis of the reaction: 3-hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA + 4 H+ = 7-methyl-3-oxooct-6-enoyl-CoA + acetate.


name: 4-cresol dehydrogenase (hydroxylating) activity

description: Catalysis of the reaction: 4-cresol + acceptor + H2O = 4-hydroxybenzaldehyde + reduced acceptor.


eosinophil activation

description: The change in morphology and behavior of a eosinophil resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.


name: oxidoreductase activity, acting on the CH-NH2 group of donors

description: Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.


name: pigment accumulation in tissues in response to UV light

description: The aggregation of coloring matter in a particular location in a tissue, occurring in response to a UV light stimulus.


name: activated CD4-positive, alpha-beta T cell apoptotic process

description: Any apoptotic process in an activated CD4-positive, alpha-beta T cell.


name: positive regulation of mesodermal to mesenchymal transition involved in gastrulation

description: Any process that increases the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition where a mesodermal cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell as part of the process of gastrulation.


name: cyanidin 3-O-glucoside 5-O-glucosyltransferase (sinapoyl-glucose dependent) activity

description: Catalysis of the reaction: cyanidin 3-O-beta-D-glucoside betaine + 1-O-sinapoyl-beta-D-glucose = cyanin betaine + trans-sinapate + H+.


long-term memory

description: The memory process that deals with the storage, retrieval and modification of information a long time (typically weeks, months or years) after receiving that information. This type of memory is typically dependent on gene transcription regulated by second messenger activation.


PKR/eIFalpha signaling

description: An intracellular signaling cassette that starts with activation and autophosphorylation of PKR (also known as EIF2AK2), which phosphorylates proteins including the translation initiation factor eIF2 to inhibit translation. PKR is activated by stress signals and during the antiviral response, activated by binding to viral double-stranded RNA (dsRNA) leading to inhibition of protein synthesis during viral infection.


name: positive regulation of mast cell apoptotic process

description: Any process that activates or increases the frequency, rate, or extent of mast cell apoptotic process.


charged-tRNA amino acid modification

description: The covalent alteration of an amino acid charged on a tRNA before it is incorporated into a protein, as in N-formylmethionine, selenocysteine or pyrrolysine.


name: negative regulation of endothelial cell apoptotic process

description: Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell apoptotic process.


name: positive regulation of mesoderm formation

description: Any process that activates or increases the frequency, rate or extent of mesoderm formation.


contact guidance

description: Cell recognition involving the deposition of specific pathways in the extracellular matrix that guide migrating cells.


name: regulation of long-term neuronal synaptic plasticity

description: A process that modulates long-term neuronal synaptic plasticity, the ability of neuronal synapses to change long-term as circumstances require. Long-term neuronal synaptic plasticity generally involves increase or decrease in actual synapse numbers.


name: negative regulation of glomerular filtration

description: Any process that stops, prevents, or reduces the frequency, rate or extent of glomerular filtration. Glomerular filtration is the process whereby blood is filtered by the glomerulus into the renal tubule.


name: double fertilization forming two zygotes

description: Rudimentary double fertilization where one of the two sperm nuclei from the pollen tube fuses with the egg nucleus to form a 2n zygote, and the other fuses with the ventral canal cell nucleus to form a second zygote, which soon degenerates. An example of this process is found in the Gnetophytes, such as Welwitschia mirabilis.


photoreceptor cell fate determination

description: The process in which a cell becomes capable of differentiating autonomously into a photoreceptor cell regardless of its environment; upon determination, the cell fate cannot be reversed.


name: tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation

description: The process whereby a wobble base uridine residue in a tRNA is modified to 5-methoxycarbonylmethyl-2-thiouridine.


name: envenomation resulting in modulation of blood coagulation in another organism

description: A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the modulation of the frequency, rate or extent of blood coagulation in the bitten organism.


name: posterior lateral line neuromast primordium migration

description: The migration of a relatively undifferentiated cell along the developing posterior lateral line, originating from cranial ectodermal placodes situated behind the ear. The neuromast primordium deposits proneuromasts along the lateral line, from which the neuromasts will develop.


name: GABAergic neuron differentiation in basal ganglia

description: The process in which a neuroblast acquires the specialized structural and functional features of a GABAergic inhibitory neuron in the basal ganglia. Differentiation includes the processes involved in commitment of a neuroblast to a GABAergic neuron.


curcumin synthase activity

description: Catalysis of the reaction: feruloylacetyl-CoA + feruloyl-CoA(4-) + H2O = curcumin + 2 coenzyme A(4-) + carbon dioxide.


regulation of oxidoreductase activity

description: Any process that modulates the frequency, rate or extent of oxidoreductase activity, the catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.


name: interneuron-substratum interaction involved in interneuron migration from the subpallium to the cortex

description: The process in which migrating interneurons interact with an external substratum as a component of migration from the subpallium to the cortex.


name: regulation of toll-like receptor 10 signaling pathway

description: Any process that modulates the frequency, rate, or extent of toll-like receptor 10 signaling pathway.


neuroblast division in subpallium

description: The division of neuroblasts in the subpallium area of the forebrain. The interneuron precursors that these cells give rise to include GABAergic interneurons and will migrate tangentially.


name: positive regulation of activated CD8-positive, alpha-beta T cell apoptotic process

description: Any process that activates or increases the frequency, rate or extent of activated CD8-positive, alpha-beta T cell apoptotic process.


proximal/distal axis specification

description: The establishment, maintenance and elaboration of the proximal/distal axis. The proximal/distal axis is defined by a line that runs from main body (proximal end) of an organism outward (distal end).


cellular response to ketone

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ketone stimulus.


name: regulation of midbrain dopaminergic neuron differentiation

description: Any process that modulates the frequency, rate or extent of midbrain dopaminergic neuron differentiation.


name: proton-dependent oligopeptide secondary active transmembrane transporter activity

description: Enables the transfer of a oligopeptide from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by proton movement.


name: maintenance of protein localization in organelle

description: Any process in which a protein is maintained in a specific location a specific location on or in an organelle, and is prevented from moving elsewhere. Encompasses establishment of localization in the membrane or lumen of a membrane-bounded organelle.


(3R)-citramalyl-CoA lyase activity

description: Catalysis of the reaction: (3R)-citramalyl-CoA = pyruvate + acetyl-CoA.


angelicin synthase activity

description: Catalysis of the reaction: columbianetin + NADPH + O2 + H+ = angelicin + acetone + NADP + 2 H2O.


name: regulation of raffinose biosynthetic process

description: Any process that modulates the frequency, rate or extent of raffinose biosynthetic process.


name: regulation of vascular associated smooth muscle contraction

description: Any process that increases the frequency, rate or extent of vascular smooth muscle contraction.


labial disc morphogenesis

description: The process in which the anatomical structures derived from the labial disc are generated and organized. This includes the transformation of a labial imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into recognizable adult structures including parts of the proboscis.


threonine synthase activity

description: Catalysis of the reaction: O-phospho-L-homoserine + H2O = L-threonine + phosphate.


name: positive regulation of iodide transmembrane transport

description: Any process that activates or increases the frequency, rate or extent of iodide transmembrane transport.


cell cycle DNA replication initiation

description: Any DNA replication initiation that is involved in cell cycle DNA replication.


name: high-affinity L-histidine transmembrane transporter activity

description: Enables the transfer of L-histidine from one side of a membrane to the other. L-histidine is 2-amino-3-(1H-imidazol-4-yl)propanoic acid. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.


petal epidermis patterning

description: The regionalization process that regulates the coordinated growth and establishes the non-random spatial arrangement of the cells in the petal epidermis.


bacillithiol biosynthetic process

description: The chemical reactions and pathways resulting in the formation of bacillithiol, the alpha-anomeric glycoside of L-cysteinyl-D-glucosamine with L-malic acid. Bacillithiol, produced widely in the Firmicutes and sporadically in other bacterial lineages, is a low-molecular-weight thiol analogous to mycothiol in the Actinomycetes and glutathione in many species.


name: metanephric long descending thin limb bend development

description: The process whose specific outcome is the progression of the metanephric long descending thin limb bend over time, from its formation to the mature structure. The metanephric long descending thin limb bend is a part of the descending thin limb of a long nephron that lies beyond the prebend segment in the metanephros.


name: negative regulation of (+)-kotanin biosynthetic process

description: Any process that stops, prevents or reduces the frequency, rate or extent of (+)-kotanin biosynthetic process.


regulation of galactotriose transport

description: Any process that modulates the frequency, rate or extent of galactotriose transport.


6-carboxyhexanoate-CoA ligase activity

description: Catalysis of the reaction: ATP + CoA + pimelate = AMP + diphosphate + H+ + pimelyl-CoA.


name: apoptotic process involved in heart morphogenesis

description: Any apoptotic process that contributes to the shaping of the heart.


name: high-density lipoprotein particle assembly

description: The non-covalent aggregation and arrangement of proteins and lipids to form a high-density lipoprotein particle.


longitudinal axis specification

description: The establishment, maintenance and elaboration of the longitudinal axis. In plants, this is the axis that runs from the shoot to the root.


notochord cell vacuolation

description: The assembly and arrangement of a vacuole within a cell of the notochord.


name: negative regulation of phenazine biosynthetic process

description: Any process that stops, prevents or reduces the frequency, rate or extent of phenazine biosynthetic process.


name: isocitrate dehydrogenase (NAD+) activity

description: Catalysis of the reaction: isocitrate + NAD+ = 2-oxoglutarate + CO2 + NADH.


midbrain-hindbrain boundary maturation

description: A developmental process, independent of morphogenetic (shape) change, that is required for the midbrain-hindbrain boundary to attain its fully functional state. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate.


regulation of fucose catabolic process

description: Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of fucose.


name: positive regulation of defense response to insect

description: Any process that activates or increases the frequency, rate or extent of defense response to insect.


name: adenylate cyclase-activating dopamine receptor signaling pathway

description: An adenylate cyclase-activating G protein-coupled receptor signaling pathway initiated by dopamine binding to its receptor, and ending with the regulation of a downstream cellular process.


name: positive regulation of R7 cell fate commitment

description: Any process that activates or increases the frequency, rate or extent of R7 cell fate commitment.


glycerol kinase activity

description: Catalysis of the reaction: ATP + glycerol = sn-glycerol 3-phosphate + ADP + 2 H+.


beta-curcumene synthase activity

description: Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate(3-) = diphosphoric acid + (-)-beta-curcumene.


name: negative regulation of protein import into nucleus during spindle assembly checkpoint

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the movement of proteins from the cytoplasm into the nucleus, and that occurs as a response to the mitotic cell cycle spindle assembly checkpoint. In S. cerevisiae, this process involves inhibition of the karyopherin/importin Kap121p (also known as Pse1p), which acts as the specific nuclear import receptor for several proteins, including Glc7p. Glc7p functions in opposition to key spindle assembly checkpoint protein Aurora kinase (Ipl1p).


prostate gland epithelium morphogenesis

description: The process in which the anatomical structures of epithelia of the prostate gland are generated and organized. An epithelium consists of closely packed cells arranged in one or more layers, that covers the outer surfaces of the body or lines any internal cavity or tube.


description: Catalysis of the reaction: alpha-D-galactose 1-phosphate + UDP-D-glucose = alpha-D-glucose 1-phosphate + UDP-D-galactose.


name: suppression of platelet aggregation in another organism

description: Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of platelet aggregation in a second organism.


name: regulation of sporulation resulting in formation of a cellular spore

description: Any process that modulates the frequency, rate or extent of spore formation.


flavonoid phytoalexin metabolic process

description: The chemical reactions and pathways involving flavonoid phytoalexins, a group of water-soluble phenolic derivatives containing a flavan skeleton, which possess antibiotic activity and are produced by plant tissues in response to infection.


ubiquitin recycling

description: Any process involved in the maintenance of an internal steady state of ubiquitin monomers and free ubiquitin chains at the level of the cell by recycling ubiquitin from proteasome-bound ubiquitinated intermediates.


glucosaminate ammonia-lyase activity

description: Catalysis of the reaction: D-glucosaminate = 2-dehydro-3-deoxy-D-gluconate + NH3.


pentose catabolic process

description: The chemical reactions and pathways resulting in the breakdown of a pentose, any monosaccharide with a chain of five carbon atoms in the molecule.


outer ear unfolding

description: The opening and spreading out of the outer ear.


name: symbiont-mediated suppression of host resistance gene-dependent defense response

description: A process in which a symbiont inhibits or disrupts the normal execution of the resistance gene-dependent defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.


coronary sinus valve formation

description: The developmental process pertaining to the initial formation of the coronary sinus valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable.


description: Catalysis of the reaction: 1-hydroxy-4,4-dimethylpentan-3-one = 4,4-dimethyl-3-oxopentanal + 2 H+ + 2 e-.


name: negative regulation of cellodextrin metabolic process

description: Any process that stops, prevents or reduces the frequency, rate or extent of cellodextrin metabolic process.


response to water

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of water.


name: 3-hydroxypropionate dehydrogenase (NAD+) activity

description: Catalysis of the reaction: 3-hydroxypropanoate + NAD+ = 3-oxopropanoate + H+ + NADH.


name: regulation of hippocampal neuron apoptotic process

description: Any process that modulates the occurrence or rate of cell death by apoptotic process in hippocampal neurons.


name: negative regulation of cardioblast differentiation

description: Any process that stops, prevents, or reduces the frequency, rate or extent of cardioblast differentiation, the process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.


peptidyl-lysine butyrylation

description: The butyrylation of a lysine residue in a protein. Butyryl is the univalent radical C3H7COO- derived from butyric acid.


insecticide metabolic process

description: The chemical reactions and pathways involving insecticides, chemicals used to kill insects.


name: polyvinyl alcohol dehydrogenase (cytochrome) activity

description: Catalysis of the reaction: polyvinyl alcohol + ferricytochrome c = oxidized polyvinyl alcohol + ferrocytochrome c + H+.


regulation of timing of anagen

description: Any process that modulates the frequency, rate or extent of timing of anagen, the growth phase of the hair cycle.


name: regulation of natural killer cell tolerance induction

description: Any process that modulates the frequency, rate, or extent of natural killer cell tolerance induction.


name: regulation of tocopherol cyclase activity

description: Any process that modulates the frequency, rate or extent of tocopherol cyclase activity.


name: L-histidine catabolic process to 2-oxoglutarate

description: The chemical reactions and pathways resulting in the breakdown of L-histidine into other compounds, including 2-oxoglutarate.


name: antigen processing and presentation of exogenous peptide antigen via MHC class Ib

description: The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class Ib protein complex. The peptide is typically a fragment of a larger exogenous protein which has been degraded within the cell. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family.


name: asexual sporulation resulting in formation of a cellular spore

description: The formation of a cellular spore derived from the products of mitosis. A cellular spore is a cell form that can be used for dissemination, for survival of adverse conditions because of its heat and desiccation resistance, and/or for reproduction.


fruit ripening, non-climacteric

description: A fruit ripening process that does not involve a respiratory burst.


name: positive regulation of tetrapyrrole metabolic process

description: Any process that activates or increases the frequency, rate or extent of tetrapyrrole metabolic process.


regulation of homophilic cell adhesion

description: Any process that modulates the frequency, rate or extent of homophilic cell adhesion.


description: The chemical reactions and pathways resulting in the formation of (1->6)-beta-D-glucans.


citronellal dehydrogenase activity

description: Catalysis of the reaction: citronellal + NAD+ + OH- = citronellate + NADH + H+.


name: regulation of intrinsic apoptotic signaling pathway in response to DNA damage

description: Any process that modulates the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to DNA damage.


name: positive regulation of inosine transport

description: Any process that activates or increases the frequency, rate or extent of the directed movement of inosine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


depsipeptide catabolic process

description: The chemical reactions and pathways resulting in the breakdown of depsipeptides, a linear or cyclic compound composed of both amino acids and hydroxy acids in peptide and ester bonds respectively.


name: cellular response to nerve growth factor stimulus

description: A process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nerve growth factor stimulus.


name: modulation of inhibitory postsynaptic potential

description: Any process that modulates the frequency, rate or extent of inhibitory postsynaptic potential (IPSP). IPSP is a temporary decrease in postsynaptic membrane potential due to the flow of negatively charged ions into the postsynaptic cell. The flow of ions that causes an IPSP is an inhibitory postsynaptic current (IPSC) and makes it more difficult for the neuron to fire an action potential.


name: protein localization to Mei2 nuclear dot

description: A process in which a protein is transported to, or maintained in, a location within a Mei2 nuclear dot.


pollen maturation

description: The final stages of microgametogenesis after the trinucleate stage has been reached resulting in viable pollen grains.


phospholipid homeostasis

description: Any process involved in the maintenance of an internal steady state of phospholipid within an organism or cell.


modification of dendritic spine

description: Any process that modifies the structure of a dendritic spine.


adenine catabolic process

description: The chemical reactions and pathways resulting in the breakdown of adenine, 6-aminopurine, one of the 5 main bases found in nucleic acids and a component of numerous important derivatives of its corresponding ribonucleoside, adenosine.


name: cell wall macromolecule catabolic process

description: The chemical reactions and pathways resulting in the breakdown of macromolecules that form part of a cell wall.


description: Catalysis of the reaction: fumarate + n-hexane = (1-methylpentyl)succinate.


name: anaerobic carbon tetrachloride metabolic process

description: The chemical reactions and pathways involving carbon tetrachloride, a toxic, carcinogenic compound which is used as a general solvent in industrial degreasing operations, that occur in the absence of oxygen.


murein hydrolase activity

description: Catalysis of the reaction: a peptidoglycan dimer (generic) = a lipid II + GlcNAc-1,6-anhydro-MurNAc-pentapeptide.


tauropine dehydrogenase activity

description: Catalysis of the reaction: H2O + NAD+ + tauropine = H+ + NADH + pyruvate + taurine.


name: regulation of antigen receptor-mediated signaling pathway

description: Any process that modulates the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B- or T cell.