name: asymmetric protein localization involved in cell fate determination

description: Any process in which a protein is transported to, or maintained in, a specific asymmetric distribution, resulting in the formation of daughter cells of different types.


aliphatic nitrilase activity

category: biolink:MolecularActivity biolink:Occurrent biolink:OntologyClass biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: Catalysis of the reaction: R-CN + H2O = R-COOH + NH3.


S-alkylthiohydroximate lyase activity

description: Catalysis of the conversion of a S-alkylthiohydroximate to a thiohydroximate.


description: Catalysis of the reaction: 2-hydroxycyclohexan-1-one + NADPH + O2 = 6-oxohexanoate + H2O + NADP+.


atrioventricular valve development

category: biolink:BiologicalProcess biolink:Occurrent biolink:OntologyClass biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: The progression of the atrioventricular valve over time, from its formation to the mature structure.


name: spermidine oxidase (propane-1,3-diamine-forming) activity

description: Catalysis of the reaction: H2O + O2 + spermidine = 1,3-diaminopropane + 4-aminobutanal + H2O2.


name: lysine biosynthetic process via alpha-aminoadipate and N2-acetyl-alpha-aminoadipate

description: The chemical reactions and pathways resulting in the formation of lysine via the intermediates alpha-aminoadipic acid and N2-acetyl-alpha-aminoadipate. This pathway of prokaryotic lysine biosynthesis via alpha-aminoadipate was discovered in the hyper-thermophilic Gram-negative eubacterium Thermus thermophilus. The pathway proceeds as follows: alpha-ketoglutarate is converted to homocitrate, which is metabolized to 3-carboxyhex-2-enedioate and then homoisocitrate. This is then decarboxylated to form alpha-ketoadipate, which is then converted to alpha-aminoadipate. This undergoes acetylation, to form N2-acetyl-alpha-aminoadipate, and is then phosphorylated to give N2-acetyl-alpha-aminoadipyl-delta-phosphate. This is converted to N2-acetyl-alpha-aminoadipate semialdehyde, which is then converted to N2-acetyl-L-lysine. A final deacetylation reaction produces L-lysine.


ommatidial rotation

description: The process in which photoreceptors are arranged in ommatidia in the dorsal and ventral fields to be mirror images. The polarity is established in the imaginal discs concurrently with cell fate specification.


description: The phosphorylation by a protein of one or more of its own aspartate amino acid residues, or an aspartate residue on an identical protein.


name: negative regulation of the force of heart contraction by chemical signal

description: Any process which decreases the force of heart muscle contraction mediated by chemical signaling, hormonal, autocrine or paracrine.


name: positive regulation of growth of unicellular organism as a thread of attached cells

description: Any process that activates or increases the frequency, rate or extent of the process in which cells remain attached after division and form thread-like filaments that may penetrate into a solid growth medium.


geranyl diphosphate metabolic process

description: The chemical reactions and pathways involving geranyl diphosphate, the universal precursor of the monoterpenes.


anther dehiscence

description: The dehiscence of an anther to release the pollen grains contained within it.


9-fluorenone-3,4-dioxygenase activity

description: Catalysis of the reaction: 9-fluorenone + O2 + 2 H+ + 2 e- = 1-hydro-1,1a-dihydroxy-9-fluorenone.


aerobic sulfur oxidation

description: A sulfur oxidation process that proceeds via the reaction catalyzed by sulfur dioxygenase, and requires the presence of oxygen.


name: sulochrin oxidase [(-)-bisdechlorogeodin-forming] activity

description: Catalysis of the reaction: O2 + 2 sulochrin = 2 (2R)-bisdechlorogeodin + 2 H2O.


name: sodium:phosphate symporter activity

description: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Na+(out) + phosphate(out) = Na+(in) + phosphate(in).


protein-tetrapyrrole linkage

description: The covalent linking of a tetrapyrrole to a protein.


name: epithelial cell proliferation involved in Malpighian tubule morphogenesis

description: The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population and contributing to the shaping of a Malpighian tubule.


name: N-cyclopropylammelide alkylamino hydrolase activity

description: Catalysis of the reaction: N-cyclopropylammelide + H2O = cyclopropylamine + cyanuric acid.


name: squamous basal epithelial stem cell differentiation involved in prostate gland acinus development

description: The process in which a relatively unspecialized epithelial cell acquires specialized features of a squamous basal epithelial stem cell of the prostate.


name: metanephric proximal convoluted tubule segment 1 development

description: The process whose specific outcome is the progression of the S1 portion of the metanephric proximal convoluted tubule over time, from its formation to the mature structure. The S1 portion is the initial portion of the metanephric proximal convoluted tubule and is responsible for avid reabsorption of water and solutes.


nonfunctional rRNA decay

description: An rRNA catabolic process that results in the targeted detection and degradation of aberrant rRNAs contained within translationally defective ribosomes, thereby acting as a quality-control system.


cellular detoxification

description: Any process carried out at the cellular level that reduces or removes the toxicity of a toxic substance. These may include transport of the toxic substance away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance.


cellular response to retinoic acid

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a retinoic acid stimulus.


box H/ACA sno(s)RNA processing

description: Any process involved in the conversion of a primary box H/ACA type small RNA transcript into a mature box H/ACA RNA.


name: negative regulation of receptor signaling pathway via JAK-STAT

description: Any process that stops, prevents, or reduces the frequency, rate or extent of a receptor signaling pathway via JAK-STAT.


cerebellum development

description: The process whose specific outcome is the progression of the cerebellum over time, from its formation to the mature structure. The cerebellum is the portion of the brain in the back of the head between the cerebrum and the pons. In mice, the cerebellum controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills.


proline catabolic process

description: The chemical reactions and pathways resulting in the breakdown of proline (pyrrolidine-2-carboxylic acid), a chiral, cyclic, nonessential alpha-amino acid found in peptide linkage in proteins.


description: Catalysis of the reaction: 1-palmitoylglycerol-3-phosphate + NADP+ = palmitoylglycerone phosphate + NADPH + H+.


description: The covalent attachment of a palmitoyl group to a nitrogen (N) atom in an N-terminal cysteine residue to form N-palmitoyl-L-cysteine.


name: negative regulation of pro-B cell differentiation

description: Any process that stops, prevents or reduces the frequency, rate or extent of pro-B cell differentiation.


name: fatty acid methyl ester metabolic process

description: The chemical reactions and pathways involving fatty acid methyl ester.


glucocorticoid catabolic process

description: The chemical reactions and pathways resulting in the breakdown of glucocorticoids, hormonal C21 corticosteroids synthesized from cholesterol.


parietal peritoneum development

description: The process whose specific outcome is the progression of a parietal peritoneum over time, from its formation to the mature structure.


rRNA 3'-end processing

description: Any process involved in forming the mature 3' end of an rRNA molecule.


name: protein O-linked glycosylation via hydroxyproline

description: The glycosylation of proteins via 04 atom of hydroxyproline to form O4-glycosyl-L-hydroxyproline; the most common form is arabinofuranosyl-4-proline.


name: CD4-positive, alpha-beta T cell cytokine production

description: Any process that contributes to cytokine production by a CD4-positive, alpha-beta T cell.


imaginal disc lineage restriction

description: Formation and/or maintenance of a lineage boundary between compartments in an imaginal disc that cells cannot cross, thus separating the populations of cells in each compartment.


stalled ribosome sensor activity

description: A molecule that recognizes stalled ribosomes and initiates a signaling response.


intramolecular lyase activity

description: The catalysis of certain rearrangements of a molecule to break or form a ring.


name: positive regulation of homophilic cell adhesion

description: Any process that activates or increases the frequency, rate or extent of homophilic cell adhesion.


description: Catalysis of the reaction: H2O + N6-(2-hydroxyisobutanoyl)-L-lysyl-[protein] = 2-hydroxy-2-methylpropanoate + L-lysyl-[protein].


feruloyl-CoA hydratase/lyase activity

description: Catalysis of the reaction: (E)-feruloyl-CoA + H2O = acetyl-CoA + vanillin.


cochlea development

description: The progression of the cochlea over time from its formation to the mature structure. The cochlea is the snail-shaped portion of the inner ear that is responsible for the detection of sound.


3,4-dihydroxybenzoate catabolic process

description: The chemical reactions and pathways resulting in the breakdown of 3,4-dihydroxybenzoate.


DN3 thymocyte differentiation

description: The process in which a relatively unspecialized cell acquires the specialized features of a DN3 thymocyte. A DN3 thymocyte is a CD4-,CD8- thymocyte that is also CD44+,CD25+.


name: poly(A)-dependent snoRNA 3'-end processing

description: Any process involved in forming the mature 3' end of a snoRNA molecule linked to prior polyadenylation of the 3'-end of the precursor snoRNA.


dihydrofolic acid binding

description: Binding to dihydrofolic acid, a folic acid in which the bicyclic pteridine structure is in the dihydro, partially reduced form; they are intermediates in folate metabolism and are reduced to their tetrahydro, reduced forms.


dissimilatory sulfate reduction

description: The reduction of sulfate to hydrogen sulfide, which acts as a terminal electron acceptor. Sulfate is activated to adenosine-phosphosulfate (APS) which is then reduced to sulfite, which is in turn reduced to hydrogen sulfide.


neural nucleus development

description: The biological process whose specific outcome is the progression of a neural nucleus from its initial condition to its mature state. A neural nucleus is an anatomical structure consisting of a discrete aggregate of neuronal soma.


name: verbascose galactinol:ajugose galactosyltransferase activity

description: Catalysis of the reaction: verbascose + alpha-D-galactosyl-(1->3)-1D-myo-inositol = ajugose + myo-inositol.


name: regulation of Schwann cell proliferation involved in axon regeneration

description: Any process that modulates the frequency, rate or extent of Schwann cell proliferation involved in axon regeneration.


exo-alpha-(2->8)-sialidase activity

description: Catalysis of the hydrolysis of alpha-(2->8)-glycosidic linkages of terminal sialic residues in substrates.


response to biotin

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biotin stimulus.


name: negative regulation of mast cell apoptotic process

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of mast cell apoptotic process.


behavioral response to wounding

description: A behavioral response resulting from wounding.


cytoplasmic translational termination

description: The process resulting in the release of a polypeptide chain from the ribosome in the cytoplasm, usually in response to a termination codon.


cellular response to nocodazole

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nocodazole stimulus.


name: peripheral nervous system axon ensheathment

description: The process in which a Schwann cell membrane closes around an axon in the peripheral nervous system. This can be a myelinating or a non-myelinating neuron-glial interaction.


name: fibroblast growth factor receptor signaling pathway involved in mammary gland specification

category: biolink:Pathway biolink:OntologyClass biolink:BiologicalProcess biolink:Occurrent biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: The series of molecular signals initiated by binding of a fibroblast growth factor to its receptor on the surface of al cell in the epidermis resulting in the formation of the mammary line. The mammary line is a ridge of epidermal cells that will form the mammary placodes.


description: Catalysis of the reactions: a 9-cis-epoxycarotenoid + O2 = 2-cis,4-trans-xanthoxin + a 12'-apo-carotenal; 9-cis-violaxanthin + O2 = 2-cis,4-trans-xanthoxin + (3S,5R,6S)-5,6-epoxy-3-hydroxy-5,6-dihydro-12'-apo-beta-caroten-12'-al; and 9'-cis-neoxanthin + O2 = 2-cis,4-trans-xanthoxin + (3S,5R,6R)-5,6-dihydroxy-6,7-didehydro-5,6-dihydro-12'-apo-beta-caroten-12'-al.


serine 3-dehydrogenase activity

description: Catalysis of the reaction: L-serine + NADP+ = L-alpha-formylglycine + 2 H+ + NADPH.


peripheral B cell tolerance induction

description: Tolerance induction of mature B cells in the peripheral lymphoid tissues: the blood, lymph nodes, spleen, and mucosal-associated lymphoid tissue.


acquisition of seed longevity

description: The acquisition of seed longevity is the ordered series of events during seed development, that prevent embryo deterioration and ROS damage and thus contribute to seed viability over time or in response to adverse environmental conditions. These events include protective (e.g. production of glassy cytoplasm ) and repair (e.g. oxidative stress responses) processes.


name: wing disc dorsal/ventral pattern formation

description: The establishment, maintenance and elaboration of the dorsal/ventral axis of the wing disc, a precursor to the adult wing.


meristem development

description: The process whose specific outcome is the progression of the meristem over time, from its formation to the mature structure.


name: regulation of brassinosteroid mediated signaling pathway

description: Any process that modulates the frequency, rate or extent of brassinosteroid mediated signaling pathway.


myosin filament organization

description: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a filament composed of myosin molecules.


cellular response to water deprivation

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of water.


abietadiene synthase activity

description: Catalysis of the reaction: (+)-copalyl diphosphate = (-)-abietadiene + diphosphate.


tropinone reductase activity

description: Catalysis of the reaction: NADP+ + pseudotropine = H+ + NADPH + tropinone.


name: cuticle development involved in collagen and cuticulin-based cuticle molting cycle

description: Synthesis and deposition of a collagen and cuticulin-based noncellular, hardened, or membranous secretion from an epithelial sheet, occurring as part of the molting cycle. An example of this process is found in Caenorhabditis elegans.


name: regulation of inositol biosynthetic process

description: Any process that modulates the frequency, rate or extent of inositol biosynthetic process.


name: envenomation resulting in blood agglutination in another organism

description: A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with specific proteins binding to cell-surface carbohydrates and causing calcium-dependent agglutination of blood cells in the bitten organism.


description: Enables the directed movement of lysophospholipids from one side of a membrane to the other. A lysophospholipid is a phospholipid that lacks one of its fatty acyl chains; it is an intermediate formed during digestion of dietary and biliary phospholipids.


description: Catalysis of the reaction: 3-methoxy-5-hydroxytoluene + S-adenosyl-L-methionine = H+ + 3,5-dimethoxytoluene + S-adenosyl-L-homocysteine.


name: negative regulation of xenobiotic detoxification by transmembrane export across the plasma membrane

description: Any process that stops, prevents or reduces the frequency, rate or extent of xenobiotic transmembrane export. A xenobiotic is a compound foreign to the organism exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical.


L-gulonolactone oxidase activity

description: Catalysis of the reaction: L-gulono-1,4-lactone + O2 = L-xylo-hex-3-ulonolactone + H2O2.


interleukin-33 production

description: The appearance of interleukin-33 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


O-acetyltransferase activity

description: Catalysis of the transfer of an acetyl group to an oxygen atom on the acceptor molecule.


hepatic stellate cell differentiation

description: The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a hepatic stellate cell.


GARP complex binding

description: Binding to a GARP complex.


calcidiol 1-monooxygenase activity

description: Catalysis of the reaction: calcidiol + H+ + NADPH + O2 = calcitriol + H2O + NADP+.


chronic inflammatory response

description: Inflammation of prolonged duration (weeks or months) in which active inflammation, tissue destruction, and attempts at repair are proceeding simultaneously. Although it may follow acute inflammation, chronic inflammation frequently begins insidiously, as a low-grade, smoldering, often asymptomatic response.


sensory processing

description: Any neural process required for an organism to sense and interpret the dimensions of a sensory experience: modality, location, intensity and affect.


name: cell differentiation involved in pronephros development

description: The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the pronephros as it progresses from its formation to the mature state.


amphiregulin production

description: The appearance of amphiregulin due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Amphiregulin (AREG) is a ligand of the epidermal growth factor receptor (EGFR), a widely expressed transmembrane tyrosine kinase. AREG is synthesized as a membrane-anchored precursor protein that can engage in juxtacrine signaling on adjacent cells. Alternatively, after proteolytic processing by cell membrane proteases, mainly TACE/ADAM17, AREG is secreted and behaves as an autocrine or paracrine factor.


name: positive regulation of blood pressure in another organism

description: A process by which one organism increases the force with which blood travels through the circulatory system of another organism.


mitochondrial ncRNA surveillance

description: The set of processes involved in identifying and degrading defective or aberrant non-coding RNA transcripts (ncRNAs) within the mitochondrion.


foraging behavior

description: Behavior by which an organism locates food.


name: regulation of calcidiol 1-monooxygenase activity

description: Any process that modulates the rate, frequency or extent of calcidiol 1-monooxygenase activity. Calcidiol 1-monooxygenase activity is catalysis of the reaction: calcidiol + NADPH + H+ + O2 = calcitriol + NADP+ + H2O.


sepal giant cell differentiation

description: The process in which a relatively unspecialized cell acquires specialized features of a sepal giant cell. A sepal giant cell is a pavement cell that is part of the sepal epidermis and stretches one fifth the length of the sepal with a chromosome content of 16C.


positive regulation of cell size

description: Any process that increases cell size.


name: ureter smooth muscle cell differentiation

description: The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell in the ureter.


name: regulation of monoatomic anion transport

description: Any process that modulates the frequency, rate or extent of the directed movement of anions, atoms or small molecules with a net negative charge into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


cellular response to leucine starvation

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of leucine.


name: regulation of intestinal epithelial cell development

description: Any process that modulates the frequency, rate or extent of intestinal epithelial cell development.


description: Catalysis of the reaction: 4-coumaroyl-CoA + a flavonol 3-O-[beta-D-glucosyl-(1->2)-beta-D-glucosyl-(1->2)-beta-D-glucoside] = CoA + a flavonol 3-O-[6-(4-coumaroyl)-beta-D-glucosyl-(1->2)-beta-D-glucosyl-(1->2)-beta-D-glucoside].


name: MAPK-activating adrenergic receptor signaling pathway

description: The series of molecular signals generated as a consequence of an adrenergic receptor binding to its physiological ligand and leading to the activation of a MAP kinase cascade.


name: positive regulation of protein kinase C signaling

description: Any process that increases the frequency, rate, or extent of a series of reactions, mediated by the intracellular serine/threonine kinase protein kinase C, which occurs as a result of a single trigger reaction or compound.


protein insertion into membrane raft

description: The process in which a protein is incorporated into a membrane raft. Membrane rafts are small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes.


cellobiose binding

description: Binding to cellobiose, a disaccharide that represents the basic repeating unit of cellulose.


receptor catabolic process

description: The chemical reactions and pathways resulting in the breakdown of a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.


name: symbiont-mediated suppression of host translation elongation

description: A process in which a symbiont inhibits or disrupts the translation elongation of host mRNA into protein, for example by directly inhibiting elongation factors. The host is defined as the larger of the organisms involved in a symbiotic interaction.


description: Catalysis of the reaction: L-arginyl-[protein] + NAD+ = H+ + (ADP-D-ribosyl)-L-arginyl-[protein] + nicotinamide.


description: Catalysis of the reaction: N-methyl-3-aminomethylindole + S-adenosyl-L-methionine = H+ + gramine + S-adenosyl-L-homocysteine.


vestibulocochlear nerve morphogenesis

description: The process in which the anatomical structure of the vestibulocochlear nerve is generated and organized. This sensory nerve innervates the membranous labyrinth of the inner ear. The vestibular branch innervates the vestibular apparatus that senses head position changes relative to gravity. The auditory branch innervates the cochlear duct, which is connected to the three bony ossicles which transduce sound waves into fluid movement in the cochlea.


name: regulation of retinal cell programmed cell death

description: Any process that modulates the frequency, rate or extent of programmed cell death that occurs in the retina.


name: iron incorporation into iron-sulfur cluster via pentakis-L-cysteinyl L-histidino nickel tetrairon pentasulfide

description: The incorporation of iron into a nickel-iron-sulfur cluster via pentakis-L-cysteinyl L-histidino nickel tetrairon pentasulfide, found in carbon monoxide dehydrogenase.


name: somatic diversification of immune receptors by N region addition

description: The addition of variable numbers of random nucleotides by terminal deoxytransferase in the N regions of heavy chain immunoglobulin and T cell receptor genes. N regions are found at the V-D, D-D, V-J, and D-J recombinational junctions, depending on the immune receptor gene.


myelination of lateral line nerve axons

description: The formation of compact myelin sheaths around the axons of a lateral line nerve.


gallate catabolic process

description: The chemical reactions and pathways resulting in the breakdown of gallate, the anion of gallic acid (3,4,5-trihydroxybenzoic acid).


name: hydrolase activity, acting on acid halide bonds, in C-halide compounds

description: Catalysis of the hydrolysis of any acid halide bond in substances containing halogen atoms in organic linkage.


name: detection of pH by chemoreceptor signaling

description: The process in which information about the levels of hydrogen ions are received and are converted to a molecular signal by chemoreceptors.


nematode pharynx morphogenesis

description: The process in which the anatomical structures of the nematode pharynx are generated and organized.


monoacylglycerol metabolic process

description: The chemical reactions and pathways involving monoacylglycerol, any ester of glycerol in which any one of its hydroxyl groups has been acylated with a fatty acid, the other being non-esterified.


name: mammary gland branching involved in pregnancy

description: The process in which the branching structure of the mammary gland duct is generated and organized as a part of pregnancy.


amyloid-beta formation

description: The generation of amyloid-beta by cleavage of the amyloid precursor protein (APP).


KDEL sequence binding

description: Binding to a KDEL sequence, the C terminus tetrapeptide sequence Lys-Asp-Glu-Leu found in proteins that are to be retained in the endoplasmic reticulum.


arginine catabolic process

description: The chemical reactions and pathways resulting in the breakdown of arginine, 2-amino-5-(carbamimidamido)pentanoic acid.


peptidyl-histidine methylation

description: The methylation of peptidyl-L-histidine to form peptidyl-L-1'-methyl-L-histidine (otherwise known as tau-methylhistidine, tele-methylhistidine) or peptidyl-L-3'-methyl-L-histidine (otherwise known as pi-methylhistidine, pros-methylhistidine).


name: epithelial cell differentiation involved in embryonic placenta development

description: The process in which a trophoblast cell acquires specialized features of an epithelial cell of the placental labyrinthine layer.


name: principal sensory nucleus of trigeminal nerve development

description: The process whose specific outcome is the progression of the pontine nucleus over time, from its formation to the mature structure.


regulation of NK T cell differentiation

description: Any process that modulates the frequency, rate or extent of natural killer T cell differentiation.


regulation of lymphangiogenesis

description: Any process that modulates the frequency, rate or extent of lymphangiogenesis.


name: exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

description: Exonucleolytic digestion of a pre-rRNA molecule to generate the mature 3'-end of a 5.8S rRNA molecule derived from an originally tricistronic pre-rRNA transcript that contained the Small Subunit (SSU) rRNA, the 5.8S rRNA, and the Large Subunit (LSU) rRNA in that order from 5' to 3' along the primary transcript.


name: negative regulation of asexual reproduction

description: Any process that stops, prevents or reduces the frequency, rate or extent of asexual reproduction.


NAD-cap decapping

description: Cleavage of the 5'-NAD-cap of an RNA. The NAD-cap is present at the 5'-end of some RNAs in both bacetria and eukaryotes. While it promotes RNA stability in bacteria, it promotes RNA decay in eukaryotes.


keratinocyte differentiation

description: The process in which a relatively unspecialized cell acquires specialized features of a keratinocyte.


name: regulation of cell wall integrity MAPK cascade

description: Any process that modulates the frequency, rate or extent of MAPK cascade involved in cell wall organization or biogenesis.


name: PSII associated light-harvesting complex II catabolic process

description: The chemical reactions and pathways resulting in the breakdown of one or more components of the light-harvesting complex of photosystem II.


name: extracellular ammonia-gated monoatomic ion channel activity

description: Enables the transmembrane transfer of an ion by a channel that opens when extracellular ammonia (NH3) has been bound by the channel complex or one of its constituent parts.


description: Catalysis of the reaction: 2-oxoglutarate + L-histidine = 3-(imidazol-5-yl)pyruvate + L-glutamate.


guanine salvage

description: Any process that generates guanine, 2-amino-6-hydroxypurine, from derivatives of it without de novo synthesis.


camalexin metabolic process

description: The chemical reactions and pathways involving camalexin, an indole phytoalexin.


name: positive regulation of leukocyte proliferation

description: Any process that activates or increases the frequency, rate or extent of leukocyte proliferation.


dimethylmaleate hydratase activity

description: Catalysis of the reaction: (2R,3S)-2,3-dimethylmalate = dimethylmaleate + H2O.


monocyte homeostasis

description: The process of regulating the proliferation and elimination of monocytes such that the total number of monocytes within a whole or part of an organism is stable over time in the absence of an outside stimulus.


name: poly(ribitol phosphate) teichoic acid metabolic process

description: The chemical reactions and pathways involving poly(ribitol phosphate) teichoic acid.


description: Catalysis of the reaction: homocystine + 2 reduced glutathione = oxidized glutathione + 2 homocysteine.


regulation of necroptotic process

description: Any process that modulates the rate, frequency or extent of a necroptotic process, a necrotic cell death process that results from the activation of endogenous cellular processes, such as signaling involving death domain receptors or Toll-like receptors.


name: nicotinic acid riboside metabolic process

description: The chemical reactions and pathways involving nicotinic acid riboside, the product of the formation of a glycosidic bond between ribose and nicotinic acid.


name: positive regulation of egg-laying behavior

description: Any process that activates or increases the frequency, rate or extent of oviposition.


GPCR sweet taste receptor activity

description: A G protein-coupled receptor activity that is responsible for the sense of sweet taste.


name: thiamine transmembrane transporter activity

description: Enables the transfer of thiamine from one side of a membrane to the other. Thiamine is vitamin B1, a water soluble vitamin present in fresh vegetables and meats, especially liver.


name: sulfur incorporation into metallo-sulfur cluster

description: The incorporation of exogenous sulfur into a metallo-sulfur cluster.


histone H4K5 acetyltransferase activity

description: Catalysis of the reaction: acetyl-CoA + histone H4 L-lysine (position 5) = CoA + histone H4 N6-acetyl-L-lysine (position 5).


name: cellular response to non-ionic osmotic stress

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of non-ionic solutes (e.g. mannitol, sorbitol) in the environment.


name: tRNA (uracil(54)-C5)-methyltransferase activity, 5,10-methylenetetrahydrofolate-dependent

description: Catalysis of the reaction: 5,10-methylenetetrahydrofolate + tRNA containing uridine at position 54 + FADH + H+ = tetrahydrofolate + tRNA containing ribothymidine at position 54 + FAD+.


superoxide dismutase activity

description: Catalysis of the reaction: 2 superoxide + 2 H+ = O2 + hydrogen peroxide.


mesodermal cell fate commitment

description: The cell differentiation process that results in commitment of a cell to become part of the mesoderm.


alpha-zeacarotene catabolic process

description: The chemical reactions and pathways resulting in the breakdown of alpha-zeacarotene.


D-leucine metabolic process

description: The chemical reactions and pathways involving D-leucine.


name: regulation of filamentous growth of a population of unicellular organisms in response to starvation

description: Any process that modulates the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to starvation.


response to benzene

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a benzene stimulus.


dibenzothiophene desulfurization

description: The removal of the sulfur atom from dibenzothiophene, a substance composed of two benzene rings linked by one sulfide bond and one carbon-carbon bond.


trimethylarsine oxidase activity

description: Catalysis of the reaction: trimethylarsine oxide + 2 H+ + 2 e- = trimethylarsine + H2O.


description: Catalysis of the reaction: 5-amino-4-chloro-2-(2,3-dihydroxyphenyl)pyridazin-3(2H)-one + O2 = 5-amino-4-chloro-2-(2-hydroxymuconoyl)pyridazin-3(2H)-one + 2 H+.


amino-acid betaine biosynthetic process

description: The chemical reactions and pathways resulting in the formation of any betaine, the N-trimethyl derivative of an amino acid.


polyterpenoid catabolic process

description: The chemical reactions and pathways resulting in the breakdown of polyterpenoid compounds, terpenoids with more than eight isoprene units.


name: regulation of signal transduction by p53 class mediator

description: Any process that modulates the frequency, rate or extent of signal transduction by p53 class mediator.


name: determination of digestive tract left/right asymmetry

description: Determination of the asymmetric location of various parts of the digestive tract with respect to the left and right halves of the organism. The digestive tract is the anatomical structure through which food passes and is processed.


establishment of Golgi localization

description: The directed movement of the Golgi to a specific location.


grooming behavior

description: The specific behavior of an organism relating to grooming, cleaning and brushing to remove dirt and parasites.


helper T cell extravasation

description: The migration of a helper T cell from the blood vessels into the surrounding tissue. A helper T-cell is an effector T cell that provides help in the form of secreted cytokines to other immune cells.


name: induction of conjugation upon carbon starvation

description: The process in which a cell initiates conjugation with cellular fusion upon carbon starvation.


name: metalloendopeptidase activity involved in amyloid precursor protein catabolic process

description: Any metalloendopeptidase activity that is involved in amyloid precursor protein catabolic process.


pantothenate kinase activity

description: Catalysis of the reaction: ATP + pantothenate = ADP + D-4'-phosphopantothenate.


name: positive regulation of response to salt stress

description: Any process that activates or increases the frequency, rate or extent of response to salt stress.


name: histone H3K27me2/H3K27me3 demethylase activity

description: Catalysis of the removal of a methyl group from a tri- or a dimethyl-lysine residue at position 27 of the histone H3 protein. This is a dioxygenase reaction that is dependent on Fe(II) and 2-oxoglutarate.


cellular response to bile acid

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bile acid stimulus.


name: box C/D methylation guide snoRNP complex binding

description: Binding to a box C/D methylation guide snoRNP complex.


description: Catalysis of the reaction: nicotinate + UDP-D-glucose = N-(beta-D-glucosyl)nicotinate + UDP.


name: DNA synthesis involved in double-strand break repair via homologous recombination

description: The synthesis of DNA that contributes to the process of double-strand break repair via homologous recombination.


name: negative regulation of AV node cell action potential

description: Any process that stops, prevents or reduces the frequency, rate or extent of AV node cell action potential.


description: Catalysis of the reaction 6-deoxy-6-sulfofructose-1-phosphate = 3-sulfolactaldehyde + dihydroxyacetone phosphate.


description: Catalysis of the reaction: agmatine + S-adenosylmethioninamine = N1-aminopropylagmatine + 5'-methylthioadenosine.


name: adaptive immune response based on somatic recombination of immune receptors built from leucine-rich repeat domains

description: An immune response mediated by lymphocytes expressing specific receptors for antigen produced through a somatic diversification process that includes somatic recombination of variable lymphocyte receptors (VLR) incorporating leucine-rich repeat (LRR) domains, and allowing for enhanced responses upon subsequent exposures to the same antigen (immunological memory). Examples of this process are found in jawless fish, including the lampreys (Petromyzontidae) and hagfishes (Myxinidae).


name: cell cycle DNA replication maintenance of fidelity

description: Any maintenance of fidelity that is involved in cell cycle DNA replication.


name: thyroid-stimulating hormone-secreting cell differentiation

description: The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a thyroid-stimulating hormone-secreting cell. A thyroid-stimulating hormone-secreting cell is a basophil cell of the anterior pituitary that produces thyroid-stimulating hormone, thyrotrophin.


GDP-D-glucose phosphorylase activity

description: Catalysis of the reaction: GDP-alpha-D-glucose + phosphate = alpha-D-glucose-1-phosphate + GDP.


2-phenanthrol sulfotransferase activity

description: Catalysis of the reaction: 2-phenanthrol + X-SO3(-) = HX + 2-phenanthrylsulfate.


formation of animal organ boundary

description: The regionalization process that specifies animal organ primordium boundaries resulting in a restriction of organogenesis to a limited spatial domain and keeping the organ separate from surrounding tissues.


name: ATP:farnesol kinase activity

description: Catalysis of the reaction: 2-trans,-6-trans-farnesol + ATP = 2-trans,-6-trans-farnesyl monophosphate + ADP + H+.


name: gibberellin A13,oxoglutarate:oxygen oxidoreductase activity

description: Catalysis of the reaction: gibberellin A13 + 2-oxoglutarate + O2 = gibberellin A43 + succinate + carbon dioxide.


description: Catalysis of the reaction: P(1),P(4)-bis(5'-nucleosyl)tetraphosphate + H2O = NTP + NMP. Acts on bis(5'-guanosyl)-, bis(5'-xanthosyl)-, bis(5'-adenosyl)- and bis(5'-uridyl)-tetraphosphate.


name: protein localization to equatorial microtubule organizing center

description: A process in which a protein is transported to, or maintained in, a location within an equatorial microtubule organizing center.


ansamycin metabolic process

description: The chemical reactions and pathways involving ansamycins, any of a group of complex macrolactam compounds characterized by a cyclic structure in which an aliphatic ansa chain forms a bridge between two non-adjacent positions of a cyclic p-system; many exhibit antibacterial, antifungal or antitumor activity.


name: tetracyclic triterpenoid metabolic process

description: The chemical reactions and pathways involving tetracyclic triterpenoid compounds, terpenoids with six isoprene units and 4 carbon rings.


AP-3 adaptor complex binding

description: Binding to an AP-3 adaptor complex. The AP-3 adaptor complex is a heterotetrameric AP-type membrane coat adaptor complex that consists of beta3, delta, mu3 and sigma3 subunits and is found associated with endosomal membranes. In at least humans, the AP-3 complex can be heterogeneric due to the existence of multiple subunit isoforms encoded by different genes (beta3A and beta3B, mu3A and mu3B, and sigma3A and sigma3B).


name: negative regulation of osteoclast differentiation

description: Any process that stops, prevents, or reduces the frequency, rate or extent of osteoclast differentiation.


name: N-substituted formamide deformylase activity

description: Catalysis of the reaction: N-benzylformamide + H2O = formate + benzylamine.


ubiquinone binding

description: Binding to ubiquinone, a quinone derivative with a tail of isoprene units.


epi-isozizaene synthase activity

description: Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = (+)-epi-isozizaene + diphosphate.


protein farnesyltransferase activity

description: Catalysis of the reaction: farnesyl diphosphate + protein-cysteine = S-farnesyl protein + diphosphate.


response to salt stress

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.


name: positive regulation of early endosome to recycling endosome transport

description: Any process that activates or increases the frequency, rate or extent of early endosome to recycling endosome transport.


name: positive regulation of pyocyanine biosynthetic process

description: Any process that increases the frequency, rate or extent of a pyocyanine biosynthetic process.


positive regulation of neuron migration

description: Any process that activates or increases the frequency, rate or extent of neuron migration.


presynaptic signal transduction

description: Signal transduction in which the initial step occurs in a presynapse.


outer hair cell apoptotic process

description: Any apoptotic process in an outer hair cell.


name: protein localization to somatodendritic compartment

description: A process in which a protein is transported to or maintained in a location within the somatodendritic compartment.


name: detection of chemical stimulus involved in sensory perception of umami taste

description: The series of events required for a umami taste stimulus to be received and converted to a molecular signal. Umami taste is the savory taste of meats and other foods that are rich in glutamates.


regulation of phospholipase D activity

description: Any process that modulates the frequency, rate or extent of phospholipase D activity.


name: glycerol dehydrogenase (acceptor) activity

description: Catalysis of the reaction: A + glycerol = AH(2) + glycerone.


name: regulation of vascular endothelial growth factor signaling pathway

description: Any process that modulates the frequency, rate or extent of vascular endothelial growth factor signaling pathway.


name: CD8-positive, alpha-beta T cell proliferation

description: The expansion of a CD8-positive, alpha-beta T cell population by cell division.


tetrapyrrole biosynthetic process

description: The chemical reactions and pathways leading to the formation of tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next.


name: regulation of arbuscule formation for nutrient acquisition from host

description: Any process that modulates the frequency, rate or extent of symbiont arbuscule formation for nutrient acquisition from host. The host is defined as the larger of the organisms involved in a symbiotic interaction.


R-lactaldehyde reductase activity

description: Catalysis of the reaction: (R)-propane-1,2-diol + NAD+ = (R)-lactaldehyde + NADH + H+.


hydroxyectoine binding

description: Binding to hydroxyectoine.


name: innate immune response-inhibiting signal transduction

description: The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately leading to inhibition of an innate immune response.


name: negative regulation of plasmatocyte differentiation

description: Any process that stops, prevents, or reduces the frequency, rate or extent of plasmatocyte differentiation.


sucrose-phosphate synthase activity

description: Catalysis of the reaction: UDP-glucose + D-fructose 6-phosphate = UDP + sucrose 6-phosphate.


emericellin metabolic process

description: The chemical reactions and pathways involving emericellin.


name: negative regulation of pigment cell differentiation

description: Any process that stops, prevents, or reduces the frequency, rate or extent of pigment cell differentiation.


CAMKK-AMPK signaling cascade

description: The series of molecular signals in which calmodulin-dependent protein kinase activity enabled by a CAMKK directly activates an AMPK. The cascade begins with calmodulin binding calcium which in turn binds CAMKK enabling its calmodulin-dependent protein kinase activity. The cascade ends with AMP-activated protein kinase activity.


dolichyldiphosphatase activity

description: Catalysis of the reaction: dolichyl diphosphate + H2O = dolichyl phosphate + phosphate.


description: Catalysis of the reaction: 2,5-dihydroxybenzoate + UDP-alpha-D-glucose = 2,5-dihydroxybenzoate 5-O-beta-D-glucoside + UDP + H+.


diterpenoid catabolic process

description: The chemical reactions and pathways resulting in the breakdown of diterpenoid compounds, terpenoids with four isoprene units.


beta-adrenergic receptor activity

description: Combining with epinephrine or norepinephrine to initiate a change in cell activity via activation of a G protein, with pharmacological characteristics of beta-adrenergic receptors; the activity involves transmitting the signal to the Gs alpha subunit of a heterotrimeric G protein.


name: negative regulation of developmental pigmentation

description: Any process that decreases the frequency, rate or extent of the developmental process that results in the deposition of coloring matter in an organism.


5-methylcytosine metabolic process

description: The chemical reactions and pathways involving 5-methylcytosine, a methylated base of DNA.


oxidative demethylation

description: The process of removing one or more methyl groups from a molecule, involving the oxidation (i.e. electron loss) of one or more atoms in the substrate.


hydrogen dehydrogenase (NADP+) activity

description: Catalysis of the reaction: NADP+ + H2 = NADPH + H+.


TTP metabolic process

description: The chemical reactions and pathways involving TTP, ribosylthymine triphosphate.


dentate nucleus development

description: The process whose specific outcome is the progression of the dentate nucleus over time, from its formation to the mature structure.


amidophosphoribosyltransferase activity

description: Catalysis of the reaction: 5-phospho-beta-D-ribosylamine + L-glutamate + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + L-glutamine + H2O.


name: negative regulation of neuronal signal transduction

description: Any process that stops, prevents or reduces the frequency, rate or extent of neuronal signal transduction.


rhombomere 4 formation

description: The process that gives rise to rhombomere 4. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.


luciferin monooxygenase activity

description: Catalysis of the generalized reaction: luciferin + O2 = oxidized luciferin + CO2 + light. There may be additional substrates and reactants involved in the reaction. The reaction results in light emission as luciferin returns to the ground state after enzymatic oxidation.


name: positive regulation of embryonic pattern specification

description: Any process that activates or increases the frequency, rate or extent of embryonic pattern specification.


name: left ventricular cardiac muscle tissue morphogenesis

description: The process in which the anatomical structures of left cardiac ventricle muscle are generated and organized.


description: Catalysis of the reaction: acyl-[acyl-carrier protein] + O-(2-acyl-sn-glycero-3-phospho)ethanolamine = [acyl-carrier protein] + O-(1-beta-acyl-2-acyl-sn-glycero-3-phospho)ethanolamine.


name: positive regulation of apoptotic process involved in metanephric collecting duct development

description: Any process that activates or increases the frequency, rate or extent of apoptotic process involved in metanephric collecting duct development.


regulation of muscle filament sliding

description: Any process that modulates the frequency, rate or extent of muscle filament sliding.


name: tRNA-specific adenosine-37 deaminase activity

description: Catalysis of the reaction: adenosine-37 + H2O = inosine-37 + NH3, in a tRNA-Ala molecule.


description: Catalysis of the reaction: 4-hydroxyphenylacetonitrile + H+ + NADPH + O2 = 4-hydroxymandelonitrile + H2O + NADP+.


atrazine N-dealkylase activity

description: Catalysis of the reaction: atrazine + O2 + 2 H+ = deethylatrazine + acetaldehyde + H2O.


name: regulation of pulmonary blood vessel remodeling

description: Any process that modulates the frequency, rate or extent of pulmonary blood vessel remodeling.


ground tissue pattern formation

description: The regionalization process that gives rise to the patterning of the ground tissue.


description: Catalysis of the reaction: 2-hydroxyisonicotinate + acceptor + H2O = citrazinate + reduced acceptor.


name: catechol catabolic process, meta-cleavage

description: The chemical reactions and pathways resulting in the breakdown of catechol via the meta-cleavage pathway, in which the catechol aromatic ring is broken between a hydroxylated carbon atom and an adjacent unsubstituted carbon atom.


epinephrine metabolic process

description: The chemical reactions and pathways involving epinephrine, a hormone produced by the medulla of the adrenal glands that increases heart activity, improves the power and prolongs the action of muscles, and increases the rate and depth of breathing. It is synthesized by the methylation of norepinephrine.


D-serine metabolic process

description: The chemical reactions and pathways involving D-serine, the D-enantiomer of serine, i.e. (2R)-2-amino-3-hydroxypropanoic acid.


myoblast fate determination

description: The cell fate determination process in which a cell becomes capable of differentiating autonomously into a myoblast regardless of its environment; upon determination, the cell fate cannot be reversed. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.


name: cell proliferation involved in kidney development

description: The multiplication or reproduction of cells, resulting in the expansion of the population in the kidney.


response to fluoride

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fluoride stimulus.


all-trans-phytoene synthase activity

description: Catalysis of the reaction: 2 geranylgeranyl diphosphate -> all-trans-phytoene + 2 diphosphate.


U5 snRNA binding

description: Binding to a U5 small nuclear RNA (U5 snRNA).


name: establishment of bipolar cell polarity involved in cell morphogenesis

description: The specification and formation of bipolar intracellular organization or cell growth patterns that contribute to cell morphogenesis. Bipolar organization is the organization that is a mirror image along an axis from a plane.


name: copper chelate transmembrane transporter activity

description: Enables the transfer of a copper chelate from one side of a membrane to the other. A copper chelate is a heterocyclic compound having a metal ion attached by coordinate bonds to at least two nonmetal ions.


name: negative regulation of T cell differentiation

description: Any process that stops, prevents, or reduces the frequency, rate or extent of T cell differentiation.


detection of sucrose stimulus

description: The series of events in which a sucrose stimulus is received by a cell and converted into a molecular signal.


name: alpha-beta T cell activation involved in immune response

description: The change in morphology and behavior of an alpha-beta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific, leading to the initiation or perpetuation of an immune response.


name: intracellular mRNA localization involved in pattern specification process

description: Any process in which mRNA is transported to, or maintained in, a specific location within an oocyte that results in a pattern being established in the embryo.


regulation of hemocyte differentiation

description: Any process that modulates the frequency, rate or extent of hemocyte differentiation.


name: cyanidin 3,5-diglucoside glucosidase activity

description: Catalysis of the reaction: cyanin betaine + H2O = cyanidin 3-O-beta-D-glucoside betaine + beta-D-glucose.


name: nickel incorporation into iron-sulfur cluster via tris-L-cysteinyl L-cysteine persulfido bis-L-glutamato L-histidino nickel triiron disulfide trioxide

description: The incorporation of nickel into a 3Fe-2S complex by tris-L-cysteinyl L-cysteine persulfido bis-L-glutamato L-histidino nickel triiron disulfide trioxide.


mugineic-acid 3-dioxygenase activity

description: Catalysis of the reactions: mugineic acid + 2-oxoglutarate + O2 = 3-epihydroxymugineic acid + succinate + CO2.


description: Catalysis of the reaction: 3-dehydro-L-gulonate + H+ = L-xylulose + CO2.


name: negative regulation of activated CD4-positive, alpha-beta T cell apoptotic process

description: Any process that stops, prevents or reduces the frequency, rate or extent of activated CD4-positive, alpha-beta T cell apoptotic process.


cerebral cortex neuron differentiation

description: The process in which a relatively unspecialized cell acquires specialized features of a neuron residing in the cerebral cortex.


glutamate-putrescine ligase activity

description: Catalysis of the reaction: L-glutamate + ATP + putrescine = gamma-L-glutamylputrescine + ADP + 2 H+ + phosphate.


biotin carboxylase activity

description: Catalysis of the reaction: ATP + biotin-carboxyl-carrier protein + CO2 = ADP + phosphate + carboxybiotin-carboxyl-carrier protein.


L-glutamate oxidase activity

description: Catalysis of the reaction: L-glutamate + O2 + H2O = 2-oxoglutarate + NH3 + H2O2.


gastrulation with mouth forming first

description: A gastrulation process in which the initial invagination becomes the mouth and the anus forms second.


name: protein insertion into mitochondrial membrane

description: The process that results in the incorporation of a protein into a mitochondrial membrane.


name: posterior semicircular canal development

description: The progession of the posterior semicircular canal from its initial formation to the mature structure.


description: Catalysis of the reaction: microsomal-membrane protein + diphosphate = diphosphate + O-phospho-microsomal-membrane protein.


description: Catalysis of the reaction: 1-methylnaphthalene + NADH + H+ + O2 = 1-hydroxymethylnaphthalene + NAD+ + H2O.


hyaluronic acid binding

description: Binding to hyaluronic acid, a polymer composed of repeating dimeric units of glucuronic acid and N-acetyl glucosamine.


peptidyl-histidine modification

description: The modification of peptidyl-histidine.


macrophage fusion

description: The binding and fusion of a macrophage to one or more other cells to form a multinucleated cell.


glucuronan lyase activity

description: Catalysis of the reaction: (1->4)-beta-D-glucuronan = an oligosaccharide with 4-deoxy-beta-D-gluc-4-enuronosyl end + (1->4)-beta-D-glucuronan. This reaction is the eliminative cleavage of (1->4)-beta-D-glucuronans to give oligosaccharides with 4-deoxy-beta-D-gluc-4-enuronosyl groups at their non-reducing ends. Complete degradation of glucuronans results in the formation of tetrasaccharides.


description: Catalysis of the reaction: N-isopropylaniline + O2 + 2 H+ + NADH = catechol + NAD+ + isopropylamine.


name: endosulfan hemisulfate sulfatase activity

description: Catalysis of the reaction: endosulfan hemisulfate + H2O = endosulfan monoalcohol + 2 H+ + sulfate.


nitrotoluene metabolic process

description: The chemical reactions and pathways involving nitrotoluene, any methylbenzene molecule with NO2 group(s) attached.


name: positive regulation of myeloid leukocyte mediated immunity

description: Any process that activates or increases the frequency, rate, or extent of myeloid leukocyte mediated immunity.


regulation of bile acid secretion

description: Any process that modulates the frequency, rate or extent of the controlled release of bile acid from a cell or a tissue.


fumitremorgin B biosynthetic process

description: The chemical reactions and pathways resulting in the formation of the indole alkaloid fumitremorgin B.


description: Catalysis of the reaction: 4-methyloct-2-enoyl-CoA + H2O = 3-hydroxy-4-methyloctanoyl-CoA.


xanthophyll cycle

description: A cyclic series of interconversions involving three xanthophylls, violoxanthin, antheraxanthin, and zeaxanthin. The xanthophyll cycle is involved in regulating energy dissipation in light harvesting complex II.


maintenance of neuroblast polarity

description: The maintenance of the apicobasal polarity of a neuroblast cell, a progenitor of the central nervous system.


name: ATP-dependent protein-DNA unloader activity

description: Facilitating the removal of a protein or protein complex from a DNA molecule driven by ATP hydrolysis. This can be achieved for example by introducing non-canonical DNA structures or generating torque to directly inhibit a protein-DNA binding interaction.


name: glucosinolate biosynthetic process from phenylalanine

description: The chemical reactions and pathways resulting in the formation of glucosinolates from other compounds including phenylalanine.


redox taxis

description: The directed movement of a motile cell or organism in response to redox potential.


name: photosynthesis, light harvesting in photosystem I

description: After a photon of light is absorbed by one of the many chlorophyll molecules, in one of the light-harvesting complexes of an antenna on photosystem I, some of the absorbed energy is transferred to the pair of chlorophyll molecules in the reaction center.


regulation of epidermis development

description: Any process that modulates the frequency, rate or extent of epidermis development.


name: DNA synthesis involved in mitochondrial DNA replication

description: Any DNA biosynthetic process that is involved in mitochondrial DNA replication.


quinone binding

description: Binding to a quinone, any member of a class of diketones derivable from aromatic compounds by conversion of two CH groups into CO groups with any necessary rearrangement of double bonds.


name: initiation of movement involved in cerebral cortex radial glia guided migration

description: The initial stages of cell motility involved in the glial-mediated movement of cells in the developing cerebral cortex.


name: positive regulation of uracil import across plasma membrane

description: Any process that activates or increases the frequency, rate or extent of uracil import across plasma membrane.


name: endoplasmic reticulum-Golgi intermediate compartment (ERGIC) derived vesicle fusion with Golgi cis cisterna membrane

description: The joining of the lipid bilayer membrane around an ERGIC-derived vesicle to the lipid bilayer membrane around the Golgi cis cisterna. Such vesicles include COPII-coated transport vesicles involved in anterograde transport.


cysteine biosynthetic process

description: The chemical reactions and pathways resulting in the formation of cysteine, 2-amino-3-mercaptopropanoic acid.


name: mercury ion transmembrane transporter activity

description: Enables the transfer of mercury (Hg2+) ions from one side of a membrane to the other.


description: Catalysis of the reaction: 2'-deoxy-5-methyl-5'-cytidylate + ATP = 5-methyldeoxycytidine diphosphate + ADP + H+.


brexanolone metabolic process

description: The chemical reactions and pathways by which living organisms transform brexanolone.


nicotinamide metabolic process

description: The chemical reactions and pathways involving nicotinamide, pyridine-3-carboxamide, the amide of nicotinic acid. It is a member of the B complex of vitamins and occurs widely in living organisms.


name: positive regulation of luteinizing hormone secretion

description: Any process that activates or increases the frequency, rate or extent of the regulated release of luteinizing hormone.


nitrile metabolic process

description: The chemical reactions and pathways involving nitriles, an organic compound containing trivalent nitrogen attached to one carbon atom. The nitriles are named with reference to the acids produced by their decomposition; for example, hydrocyanic acid is formic nitrile, and methyl cyanide is acetic nitrile.


flavonoid binding

description: Binding to a flavonoid, a compound containing two or more aromatic rings, each bearing at least one aromatic hydroxyl and connected with a carbon bridge.


microglial cell proliferation

description: The expansion of a microglial cell population by cell division.


name: selenocysteine insertion sequence binding

description: Binding to a selenocysteine insertion sequence (SECIS), a regulatory sequence within mRNA which directs incorporation of a selenocysteine at a stop codon (UGA) during translation.


description: Catalysis of the reaction: 2,4,4-trimethyl-1-pentanol = 2,4,4-trimethylpentanal + 2 H+ + 2 e-.


name: type I hypersensitivity mediated by basophils

description: An inflammatory response driven by antigen recognition by antibodies bound to Fc receptors basophils, occurring within minutes after exposure of a sensitized individual to the antigen, and leading to the release of a variety of inflammatory mediators such as histamines.


name: negative regulation of heart rate involved in baroreceptor response to increased systemic arterial blood pressure

description: Any process that stops, prevents, or reduces the frequency, rate or extent of heart contraction as a result of the baroreceptor response to increased blood pressure.


name: CD4-positive, alpha-beta intraepithelial T cell differentiation

description: The process in which a precursor cell type acquires the specialized features of a CD4-positive, alpha-beta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways.


name: symbiont-mediated suppression of host inflammatory response

description: A process in which a symbiont inhibits or disrupts the normal execution of  inflammatory response in the host organism; the inflammatory response is the immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The host is defined as the larger of the organisms involved in a symbiotic interaction.


geranylgeranyl reductase activity

description: Catalysis of the formation of phytyl group from the stepwise reduction of a geranylgeranyl group.


DNA/RNA helicase activity

description: Unwinding of a DNA/RNA duplex, i.e. a double helix in which a strand of DNA pairs with a complementary strand of RNA, driven by ATP hydrolysis.


name: positive regulation of CD8-positive, alpha-beta T cell differentiation

description: Any process that activates or increases the frequency, rate or extent of CD8-positive, alpha-beta T cell differentiation.


name: L-leucine transmembrane transporter activity

description: Enables the transfer of L-leucine from one side of a membrane to the other. L-leucine is 2-amino-4-methylpentanoic acid.


tight junction assembly

description: A cellular process that results in the aggregation, arrangement and bonding together of a set of components to form a tight junction. A tight junction seals cells together in an epithelium in a way that prevents even small molecules from leaking from one side of the sheet to the other.


description: A lipid oxidation process proceeding through a series of three successive monooxygenations of the alpha methyl group on the C4 carbon (CH3 to CH2OH to CHO to COOH) and resulting in this overall reaction: 4,4-dimethyl-9beta,19-cyclopropylsterol + 3 NADPH + 3 H+ + 3 O2 = 4-alpha-carboxy, 4-beta-methyl-9beta,19-cyclopropylsterol + 3 NADP+ + 3 H2O.


name: negative regulation of voltage-gated potassium channel activity in another organism

description: Any process in which an organism stops, prevents or reduces the frequency, rate or extent of the activity of a voltage-gated potassium channel in another organism.


lipid ubiquitination

description: The process in which one or more ubiquitin groups are added to a lipid.


name: embryo development ending in birth or egg hatching

description: The process whose specific outcome is the progression of an embryo over time, from zygote formation until the end of the embryonic life stage. The end of the embryonic life stage is organism-specific and may be somewhat arbitrary; for mammals it is usually considered to be birth, for insects the hatching of the first instar larva from the eggshell.


DNA primase activity

description: Catalysis of the synthesis of a short RNA primer on a DNA template, providing a free 3'-OH that can be extended by DNA-directed DNA polymerases. In certain conditions, for example in response to DNA damage, some primases synthesize a DNA primer.


response to red or far red light

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a red or far red light stimulus. Red light is electromagnetic radiation of wavelength of 580-700nm. Far red light is electromagnetic radiation of wavelength 700-800nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs.


name: (R)-2-hydroxy-fatty acid dehydrogenase activity

description: Catalysis of the reaction: (R)-2-hydroxystearate + NAD+ = 2-oxostearate + H+ + NADH.


name: negative regulation of vasculature development involved in avascular cornea development in camera-type eye

description: Any negative regulation of vasculature development that is involved in developing an avascular cornea of a camera-type eye.


caudate nucleus development

description: The progression of the caudate nucleus over time from its initial formation until its mature state. The caudate nucleus is the C-shaped structures of the striatum containing input neurons involved with control of voluntary movement in the brain.


description: Catalysis of the reaction: (R)-carnitine + octanoyl-CoA = (S)-octanoylcarnitine + CoA.


mitochondrial protein catabolic process

description: The chemical reactions and pathways resulting in the breakdown of a mitochondrial protein. This process is necessary to maintain the healthy state of mitochondria and is thought to occur via the induction of an intramitochondrial lysosome-like organelle that acts to eliminate the damaged oxidised mitochondrial proteins without destroying the mitochondrial structure.


name: oxygen-dependent protoporphyrinogen oxidase activity

description: Catalysis of the reaction: 3 O2 + protoporphyrinogen IX = 3 H2O2 + protoporphyrin IX.


glutamic-type endopeptidase activity

description: Catalysis of the hydrolysis of internal peptide bonds in a polypeptide chain by a mechanism involving a glutamate/glutamine catalytic dyad.


description: Catalysis of the reaction: desacetoxyvindoline + 2-oxoglutarate + O2 = desacetylvindoline + succinate + CO2.


anoikis

description: Apoptosis triggered by inadequate or inappropriate adherence to substrate e.g. after disruption of the interactions between normal epithelial cells and the extracellular matrix.


catalytic activity, acting on a tRNA

description: Catalytic activity that acts to modify a tRNA.


name: peroxisome proliferator activated receptor signaling pathway

description: A nuclear receptor-mediated signaling pathway initiated by a ligand binding to an intracellular peroxisome proliferator activated receptor (alpha, beta or gamma) of the nuclear receptor protein family, and ending with regulation of a downstream cellular process, e.g. transcription.


name: membrane repolarization during cardiac muscle cell action potential

description: The process in which ions are transported across a membrane such that the cardiac muscle cell plasma membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential.


betaine-aldehyde dehydrogenase activity

description: Catalysis of the reaction: betaine aldehyde + NAD+ + H2O = betaine + NADH + H+.


O-glycan processing, core 1

description: The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form the core 1 O-glycan structure, Gal-beta-(1->3)-GalNAc.


description: Catalysis of the reaction: UDP-N-acetylglucosamine + Skp1-protein-hydroxyproline = UDP + Skp1-protein-O-(N-acetyl-D-glucosaminyl)hydroxyproline.


modulation of penetration peg formation

description: Any process that modulates the frequency, rate or extent of symbiont penetration peg formation for entry into host. The host is defined as the larger of the organisms involved in a symbiotic interaction.


description: Catalysis of the reaction: 10-formyltetrahydrofolate + 5'-phosphoribosyl-5-amino-4-imidazolecarboxamide = tetrahydrofolate + 5'-phosphoribosyl-5-formamido-4-imidazolecarboxamide.


name: antigen processing and presentation of endogenous peptide antigen

description: The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC protein complex. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell.


CGA codon-amino acid adaptor activity

description: A triplet codon-amino acid adaptor activity that recognizes a CGA codon.


aerobic lactate catabolic process

description: The chemical reactions and pathways resulting in the breakdown of lactate (2-hydroxypropanoic acid) in the presence of oxygen.


nitrate reductase (cytochrome) activity

description: Catalysis of the reaction: ferrocytochrome + nitrate = ferricytochrome + nitrite.


name: regulation of orcinol biosynthetic process

description: Any process that modulates the frequency, rate or extent of orcinol biosynthetic process.


memory T cell activation

description: The change in morphology and behavior of a memory T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.


cellular response to calcium ion

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus.


name: Malpighian tubule principal cell differentiation

description: The process in which a relatively unspecialized cell acquires specialized features of a Malpighian tubule principal cell. A Malpighian tubule principal cell is an epithelial secretory cell that transports cations into the lumen of the tubule.


hepatocyte homeostasis

description: Any biological process involved in the maintenance of the steady-state number of hepatocytes within a population of cells. Hepatocytes are specialized epithelial cells of the liver that are organized into interconnected plates called lobules.


chondroitin sulfotransferase activity

description: Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + chondroitin = adenosine 3',5'-bisphosphate + chondroitin sulfate.


name: oxidoreductase activity, acting on hydrogen as donor, cytochrome as acceptor

description: Catalysis of an oxidation-reduction (redox) reaction in which hydrogen acts as an electron donor and reduces a cytochrome.


detection of cell density

description: The series of events in which information about the density of cells in a population is received and converted into a molecular signal.


cellular response to dinitrophenol

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dinitrophenol stimulus.


name: negative regulation of sexual sporulation resulting in formation of a cellular spore

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the formation of cellular spores derived from the products of meiosis.


name: oligosaccharide transporting porin activity

description: Enables the transfer of oligosaccharide, sized less than 1000 Da, from one side of a membrane to the other. The transmembrane portions of porins consist exclusively of beta-strands which form a beta-barrel. They are found in the outer membranes of Gram-negative bacteria, mitochondria, plastids and possibly acid-fast Gram-positive bacteria.


description: Catalysis of the reaction: indole-3-acetate + L-valine + ATP = H+ + indole-3-acetyl-valine + AMP + diphosphoric acid.


name: guanine nucleotide transmembrane transporter activity

description: Enables the transfer of guanine nucleotides (GMP, GDP, and GTP) from one side of a membrane to the other.


amidinotransferase activity

description: Catalysis of the reversible transfer of an amidino group to an acceptor.


description: Catalysis of the reaction: succinyl-CoA + (R)-citramalate = succinate + (R)-citramalyl-CoA.


endodermal cell fate specification

description: The cell fate determination process that results in a cell becoming capable of differentiating autonomously into an endoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.


description: Catalysis of the reaction: quinolin-2-ol + NADH + H+ + O2 = 2,5,6-trihydroxy-5,6-dihydroquinoline + NAD+.


asparagine biosynthetic process

description: The chemical reactions and pathways resulting in the formation of asparagine, 2-amino-3-carbamoylpropanoic acid.


otic vesicle formation

description: The process resulting in the transition of the otic placode into the otic vesicle, a transient embryonic structure formed during development of the vertebrate inner ear.


name: glyceraldehyde-3-phosphate dehydrogenase (NADP+) (non-phosphorylating) activity

description: Catalysis of the reaction: D-glyceraldehyde 3-phosphate + H2O + NADP+ = 3-phospho-D-glycerate + 2 H+ + NADPH.


description: Catalysis of the reaction: hexose + phosphoramidate = hexose 1-phosphate + NH3.


DNA amplification

description: The process in which the number of copies of a gene is increased in certain cells as extra copies of DNA are made in response to certain signals of cell development or of stress from the environment.


D-xylose biosynthetic process

description: The chemical reactions and pathways resulting in the formation of D-xylose, a naturally occurring plant polysaccharide.


name: sulfur compound transmembrane transporter activity

description: Enables the transfer of a sulfur compound from one side of a membrane to the other.


U1 snRNP binding

description: Binding to a U1 small nuclear ribonucleoprotein particle.


name: regulation of synaptic vesicle transport

description: Any process that modulates the frequency, rate or extent of synaptic vesicle transport.


acetylcholine biosynthetic process

description: The chemical reactions and pathways resulting in the formation of acetylcholine, the acetic acid ester of the organic base choline.


trimetaphosphatase activity

description: Catalysis of the reaction: H2O + trimetaphosphate = 2 H+ + triphosphate.


histone H2A acetyltransferase activity

description: Catalysis of the reaction: acetyl-CoA + histone H2A L-lysine = CoA + histone H2A N6-acetyl-L-lysine.


malolactic enzyme activity

description: Catalysis of the reaction: malate + H+ = L-lactate + CO2.


name: regulation of cyclic-nucleotide phosphodiesterase activity

description: Any process that modulates the frequency, rate or extent of cyclic nucleotide phosphodiesterase activity, the catalysis of the reaction: nucleotide 3',5'-cyclic phosphate + H2O = nucleotide 5'-phosphate.


name: regulation of odontoblast differentiation

description: Any process that modulates the frequency, rate or extent of odontoblast differentiation.


description: The acetylation of the N-terminal lysine of proteins to form the derivative N2-acetyl-L-lysine. The occurrence of this modification has not been confirmed.


name: D-glucuronate transmembrane transporter activity

description: Enables the transfer of D-glucuronate, the D-enantiomer of glucuronate, from one side of a membrane to the other.


lung lobe morphogenesis

description: The process in which the anatomical structures of a lung lobe are generated and organized. A lung lobe is a projection that extends from the lung.


regulation of mannan catabolic process

description: Any process that modulates the frequency, rate or extent of mannan catabolic process.


name: establishment of endothelial intestinal barrier

description: The establishment of a barrier between endothelial cell layers of the intestine to exert specific and selective control over the passage of water and solutes, thus allowing formation and maintenance of compartments that differ in fluid and solute composition.


muscle attachment

description: The developmental process in which a skeletal muscle attaches to its target (such as bone or body wall).


semicircular canal development

description: The progression of the semicircular canal from its initial formation to the mature structure.


name: juvenile hormone acid methyltransferase activity

description: Catalysis of the transfer of a methyl group to juvenile hormone acid.


xanthophyll metabolic process

description: The chemical reactions and pathways involving xanthophylls, oxygen-containing carotenoids.


rRNA N-glycosylase activity

description: Catalysis of the hydrolysis of the N-glycosylic bond at A-4324 in 28S rRNA from rat ribosomes or corresponding sites in 28S RNA from other species.


name: terminal cell fate specification, open tracheal system

description: The process in which a cell in an open tracheal system becomes capable of differentiating autonomously into a terminal cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed. Terminal cells send long and bifurcated hollow branches toward target tissues to allow oxygen exchange.


ADP phosphatase activity

description: Catalysis of the reaction: ADP + H2O = AMP + phosphate + H+.


methylseleninic acid reductase activity

description: Catalysis of the reaction: NADPH + H+ + CH3SeO2H => NADP+ + CH3SeOH + H2O.


regulation of olefin metabolic process

description: Any process that modulates the frequency, rate or extent of olefin metabolic process.


glutamate-tRNA ligase activity

description: Catalysis of the reaction: ATP + L-glutamate + tRNA(Glu) = AMP + diphosphate + L-glutamyl-tRNA(Glu).


allantoin biosynthetic process

description: The chemical reactions and pathways resulting in the formation of allantoin, (2,5-dioxo-4-imidazolidinyl)urea.


name: serotonin-gated monoatomic cation channel activity

description: Enables the transmembrane transfer of a cation by a channel that opens when serotonin has been bound by the channel complex or one of its constituent parts.


description: Catalysis of the reaction: 3-isopropylbut-3-enoyl-CoA + H2O = 3-isopropylbut-3-enoic acid + CoASH.


name: eye field cell fate commitment involved in camera-type eye formation

description: The commitment of neurectodermal cells to cells of the eye field and their capacity to differentiate into eye field cells. Eye field cells are neurectodermal cells that will form the optic placode.


regulation of spore germination

description: Any process that modulates the frequency, rate or extent of spore germination.


(E)-beta-ocimene synthase activity

description: Catalysis of the reaction: geranyl diphosphate = (E)-beta-ocimene + diphosphate.


name: lavandulyl diphosphate synthase activity

description: Catalysis of the reaction: 2 dimethylallyl diphosphate = diphosphate + lavandulyl diphosphate.


gibberellin metabolic process

description: The chemical reactions and pathways involving gibberellin. Gibberellins are a class of highly modified terpenes that function as plant growth regulators.


description: Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + glycochenodeoxycholate = adenosine 3',5'-diphosphate + glycochenodeoxycholate 7-sulfate + H+.


name: regulation of Ral protein signal transduction

description: Any process that modulates the frequency, rate or extent of Ral protein signal transduction.


name: epithelial cell apoptotic process involved in palatal shelf morphogenesis

description: An apoptotic process in a palatal shelf epithelial cell that contributes to the shaping of the palatal shelf.


glycolytic fermentation to propionate

description: Glycolytic fermentation resulting in the catabolism of glucose to propionate, yielding energy in the form of ATP; an alternative to the acrylate pathway to produce propionate.


name: negative regulation of cellular response to alkaline pH

description: Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to alkalinity.


pyrene dioxygenase activity

description: Catalysis of the reaction: pyrene + 2 H+ + 2 e- + O2 = cis-4,5-dihydroxy-4,5-dihydropyrene.


muscle cell apoptotic process

description: A form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle a muscle cell and result in its death. A muscle cell is a mature contractile cell, commonly known as a myocyte, that forms one of three kinds of muscle.


ganglioside GP1c binding

description: Binding to ganglioside GP1c.


hypoxanthine oxidase activity

description: Catalysis of the reaction: hypoxanthine + H2O + O2 = xanthine + H2O2.


mechanoreceptor activity

description: Combining with a mechanical force and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity or state as part of signal transduction.


name: negative regulation of microglial cell migration

description: Any process that stops, prevents or reduces the frequency, rate or extent of microglial cell migration.


name: fatty acid transmembrane transporter activity

description: Enables the transfer of fatty acids from one side of a membrane to the other. Fatty acids are aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis.


peptidyl-serine acetylation

description: The acetylation of peptidyl-serine.


wybutosine biosynthetic process

description: The chemical reactions and pathways resulting in the formation of wybutosine, 3H-imidazo[1,2-alpha]purine-7-butanoic acid, 4,9-dihydro- alpha-[(methoxycarbonyl)amino]- 4,6-dimethyl-9-oxo- 3-beta-D-ribofuranosyl methyl ester, a modified nucleoside found in some tRNA molecules.


detection of electrical stimulus

description: The series of events by which an electrical stimulus is received and converted into a molecular signal.


name: negative regulation of transformation of host cell by virus

description: Any process that stops, prevents or reduces the frequency, rate or extent of transformation of host cell by virus.


cellular response to cordycepin

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cordycepin stimulus.


anthranilate-CoA ligase activity

description: Catalysis of the reaction: ATP + anthranilate + CoA = AMP + diphosphate + anthranilyl-CoA.


chlorophyll biosynthetic process

description: The chemical reactions and pathways resulting in the formation of chlorophyll, any compound of magnesium complexed in a porphyrin (tetrapyrrole) ring and which functions as a photosynthetic pigment, from less complex precursors.


name: aorta smooth muscle tissue morphogenesis

description: The process in which the structure of the smooth muscle tissue surrounding the aorta is generated and organized. An aorta is an artery that carries blood from the heart to other parts of the body.


description: Catalysis of the reaction: 2-oxo-3-enoate-4-benzenoid + H2O = pyruvate + benzaldehyde derivative. Substrates are (3E)-4-(5-amino-2-hydroxy-phenyl)-2-oxo-but-3-ene-1-oic-acid (forms 5-aminosalicylaldehyde) and trans-o-hydroxybenzylidenepyruvate (forms salicylaldehyde).


name: formate dehydrogenase (quinone) activity

description: Catalysis of the reaction: formate + a quinone = CO2 + a quinol.


pentraxin receptor activity

description: Combining with a pentraxin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


heme C metabolic process

description: The chemical reactions and pathways involving heme c, a derivative of heme found in cytochromes c, b4, and f.


name: vascular associated smooth muscle cell fate specification

description: The process in which a cell becomes capable of differentiating autonomously into a vascular smooth muscle cell in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed. A vascular smooth muscle cell is a non-striated, elongated, spindle-shaped cell found lining the blood vessels.


thiazole synthase activity

description: Catalysis of the reaction: 1-deoxy-D-xylulose 5-phosphate + 2-iminoacetate + thiocarboxy-adenylate-[sulfur-carrier protein ThiS] = 2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate + [sulfur-carrier protein ThiS] + 2 H2O.


name: S-nitrosoglutathione reductase (NADPH) activity

description: Catalysis of the reaction: H+ + NADPH + S-nitrosoglutathione = NADP+ + S-(hydroxysulfenamide)glutathione.


name: tellurite transmembrane transporter activity

description: Enables the transfer of tellurite from one side of a membrane to the other. Tellurite is a salt of tellurous acid or an oxide of tellurium which occurs sparingly in tufts of white or yellowish crystals.


superior vena cava morphogenesis

description: The process in which the anatomical structure of superior vena cava generated and organized. The superior vena cava is a blood vessel that transports blood from the upper body to the heart.


E-series resolvin biosynthetic process

description: The chemical reactions and pathways resulting in the formation of resolvin family E-series, hydroxy fatty acids derived from icosapentaenoic acid.


oxazole or thiazole metabolic process

description: The chemical reactions and pathways involving oxazole or thiazole, five-membered heterocyclic ring structures containing an oxygen and a sulfur, respectively, in the 1-position and a nitrogen in the 3-position.


name: 5-hydroxymethyluracil DNA N-glycosylase activity

description: Catalysis of the removal of 5-hydroxymethyluracil bases by cleaving the N-C1' glycosidic bond between the oxidized pyrimidine and the deoxyribose sugar.


name: halohydrin hydrogen-halide-lyase B activity

description: Catalysis of the elimination of HCl from a chloropropanol, yielding an epoxypropane.


cGMP binding

description: Binding to cGMP, the nucleotide cyclic GMP (guanosine 3',5'-cyclophosphate).


name: cellular response to epinephrine stimulus

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an epinephrine stimulus. Epinephrine is a catecholamine that has the formula C9H13NO3; it is secreted by the adrenal medulla to act as a hormone, and released by certain neurons to act as a neurotransmitter active in the central nervous system.


name: negative regulation of cytokinin-activated signaling pathway

description: Any process that stops, prevents, or reduces the frequency, rate or extent of cytokinin signaling.


rejection of pollen from other species

description: The recognition and rejection of pollen of one species by cells in the stigma of another species.


vestibular reflex

description: A reflex process in which a response to an angular or linear acceleration stimulus begins with an afferent nerve impulse from a receptor in the inner ear and ends with the compensatory action of eye muscles. Signaling never reaches a level of consciousness.


phosphatidylinositol transfer activity

description: Removes phosphatidylinositol from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle.


name: protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity

description: Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + lactose(out) = protein histidine + lactose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.


pulmonary myocardium development

description: The progression of the pulmonary myocardium over time, from its initial formation to the mature structure. The pulmonary myocardium is the myocardial tissue present in the pulmonary vein.


description: Catalysis of the reaction: 1-hydroxypyrene + XCH3 = 1-methoxypyrene + HX.


name: NADPH:sulfur oxidoreductase activity

description: Catalysis of the reaction: NADPH + H+ + sulfur = hydrogen sulfide + NADP+.


name: protein-containing complex assembly involved in synapse maturation

description: The aggregation, arrangement and bonding together of a set of components to form a protein complex that contributes to synapse maturation.


name: capsule polysaccharide biosynthetic process

description: The chemical reactions and pathways resulting in the formation of polysaccharides that make up the capsule, a protective structure surrounding some species of bacteria and fungi.


name: energy derivation by oxidation of reduced inorganic compounds

description: The chemical reactions and pathways by which a cell derives energy from inorganic compounds; results in the oxidation of the compounds from which energy is released.


name: platelet-derived growth factor alpha-receptor activity

description: Combining with platelet-derived growth factor isoform PDGF-AA, PDGF-BB or PDGF-AB to initiate a change in cell activity.


regulation of RNA export from nucleus

description: Any process that modulates the frequency, rate or extent of the directed movement of RNA from the nucleus to the cytoplasm.


description: Catalysis of the reaction: UDP-galactose + kaempferol = UDP + kaempferol 3-O-beta-D-galactoside.


presynapse assembly

description: The aggregation, arrangement and bonding together of a set of components to form a presynapse.


name: regulation of CD8-positive, alpha-beta T cell differentiation

description: Any process that modulates the frequency, rate, or extent of CD8-positive, alpha-beta T cell differentiation.


axon arborization

description: The process in which the terminal anatomical structures of an axon are generated and organized into branches of specialised projections, or boutons. An axon is the long process of a neuron that conducts nerve impulses, usually away from the cell body to the terminal branches.


protein alpha-1,2-demannosylation

description: The removal of one or more alpha 1,2-linked mannose residues from a mannosylated protein.


name: regulation of synaptic vesicle lumen acidification

description: Any process that modulates the frequency, rate or extent of synaptic vesicle lumen acidification.


description: Catalysis of the reaction: anthocyanidin 3,5-di-O-beta-D-glucoside + caffeoyl-CoA = pelargonidin 3-O-(6-O-caffeoyl-beta-D-glucoside) 5-O-beta-D-glucoside + coenzyme A.


description: Catalysis of the reaction: myo-inositol + UDP-galactose = O-alpha-D-galactosyl-(1,3)-1D-myo-inositol + UDP.


name: multicellular organismal-level water homeostasis

description: A chemical homeostatic process involved in the maintenance of a steady state level of water within extracellular body fluids, such as blood, xylem or phloem, of a multicellular organism. This is distinct from maintenance of cellular homeostasis, which occurs within a cell.


name: regulation of lymphocyte apoptotic process

description: Any process that modulates the occurrence or rate of lymphocyte death by apoptotic process.


exon-exon junction complex disassembly

description: The disaggregation of an exon-exon junction complex into its constituent components.


dimethylargininase activity

description: Catalysis of the reaction: N(G),N(G)-dimethyl-L-arginine + H2O = dimethylamine + L-citrulline.


description: Catalysis of the reaction: aldose 1-phosphate + NDP = phosphate + NDP-aldose.


name: ubiquinone biosynthetic process via 3,4-dihydroxy-5-polyprenylbenzoate

description: The chemical reactions and pathways resulting in the formation of ubiquinone, via the intermediates 3,4-dihydroxy-5-polyprenylbenzoate and 3-methoxy-4-hydroxy-5-polyprenylbenzoate.


name: nuclear polyadenylation-dependent snoRNA catabolic process

description: The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of a small nucleolar RNA (snoRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target snoRNA.


response to interleukin-2

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-2 stimulus.


SNARE complex disassembly

description: The disaggregation of the SNARE protein complex into its constituent components. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers.


heart jogging

description: The morphogenetic process in which the heart cone is displaced to the left with respect to the vector of the anterior-posterior axis.


name: histone H3R8 arginine deiminase activity

description: Catalysis of the reaction: H2O + histone H3 L-arginyl (position 8)= histone H3 L-citrullyl (position 8) + NH4+, resulting in histone H3 citrullination at position 8.


description: The process that gives rise to the patterns of cell differentiation that will arise in the chitin-based adult cuticle. An example of this process is adult chitin-based cuticle pattern formation in Drosophila melanogaster.


dibutyl phthalate binding

description: Binding to dibutyl phthalate, C(16)H(22)O(4).


RNA dinucleotide insertion

description: The modification of an RNA molecule by insertion of a dinucleotide.


lipopolysaccharide floppase activity

description: Enables the transfer of a lipopolysaccharide from the cytosolic to the exoplasmic leaftlet of a membrane, using energy from the hydrolysis of ATP.


response to gamma radiation

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gamma radiation stimulus. Gamma radiation is a form of electromagnetic radiation (EMR) or light emission of a specific frequency produced from sub-atomic particle interaction, such as electron-positron annihilation and radioactive decay. Gamma rays are generally characterized as EMR having the highest frequency and energy, and also the shortest wavelength, within the electromagnetic radiation spectrum.


name: negative regulation of glutamine transport

description: Any process that stops, prevents or reduces the frequency, rate or extent of glutamine transport.


name: regulation of plasma cell differentiation

description: Any process that modulates the frequency, rate or extent of plasma cell differentiation.


description: Catalysis of the reaction: AMP + diphosphate = adenine + 5-phospho-alpha-D-ribose 1-diphosphate.


hepatocyte apoptotic process

description: Any apoptotic process in a hepatocyte, the main structural component of the liver.