nucleobase biosynthetic process

description: The chemical reactions and pathways resulting in the formation of a nucleobase, a nitrogenous base that is a constituent of a nucleic acid.


CCL2-activated CCR4 signaling pathway

category: biolink:Pathway biolink:OntologyClass biolink:BiologicalProcess biolink:Occurrent biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: The series of molecular signals initiated by the binding of the C-C chemokine CCL2 to a C-C chemokine type 4 receptor (CCR4) on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.


fructose 6-phosphate metabolic process

category: biolink:BiologicalProcess biolink:Occurrent biolink:OntologyClass biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: The chemical reactions and pathways involving fructose 6-phosphate, also known as F6P. The D-enantiomer is an important intermediate in glycolysis, gluconeogenesis, and fructose metabolism.


alpha-zeacarotene metabolic process

description: The chemical reactions and pathways involving alpha-zeacarotene.


category: biolink:MolecularActivity biolink:Occurrent biolink:OntologyClass biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N2-methylguanine.


siRNA catabolic process

description: The chemical reactions and pathways resulting in the breakdown of small interfering RNA transcripts (siRNAs).


name: negative regulation of endothelial cell proliferation

description: Any process that stops, prevents, or reduces the rate or extent of endothelial cell proliferation.


name: corticosteroid receptor signaling pathway

description: A nuclear receptor-mediated signaling pathway initiated by a corticosteroid binding to an intracellular receptor of the nuclear receptor protein family, and ending with regulation of a downstream cellular process, e.g. transcription.


oxanine DNA N-glycosylase activity

description: DNA N-glycosylase activity acting on deaminated guanine where the resulting base (oxanine) is generated by NO- or HNO2-induced nitrosative deamination.


type II hypersensitivity

description: An inflammatory response resulting in cell death or dysfunction mediated by activation of the classical complement pathway or induction of effector cell phagocytosis, cytolysis mechanisms via complement or Fc receptors following the binding of antibodies to cell surface antigens on a target cell, or mediated by the direct binding of antibody to cellular receptors.


name: double-strand break repair via classical nonhomologous end joining

description: An instance of double-strand break repair via nonhomologous end joining that requires a number of factors important for V(D)J recombination, including the KU70/80 heterodimer (KU), XRCC4, ligase IV, and DNA-PKcs in mammals. It does not produce translocations (as opposed to the alternative nonhomologous end joining).


name: negative regulation of calcium-dependent ATPase activity

description: Any process that stops, prevents or reduces the frequency, rate or extent of calcium-dependent ATPase activity.


name: anaerobic phenol-containing compound biosynthetic process

description: The chemical reactions and pathways resulting in the formation of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring, in the absence of oxygen.


name: cellular stress response to acid chemical

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in cellular homeostasis caused by the chemical structure of the anion portion of a dissociated acid (rather than the acid acting as a proton donor). The acid chemical may be in gaseous, liquid or solid form.


name: positive regulation of horizontal cell localization

description: Any process that activates or increases the frequency, rate or extent of horizontal cell localization.


sperm displacement

description: The physical displacement of sperm stored from previous mating encounters.


description: Catalysis of the reaction: N(pros)-phospho-L-histidyl-[protein] + N-acetyl-D-glucosamine(out) = L-histidyl-[protein] + N-acetyl-D-glucosamine 6-phosphate(in).


female gonad morphogenesis

description: The process in which a female gonad is generated and organized.


ventral furrow formation

description: Formation of a ventral indentation (furrow) from the blastoderm epithelium, which is internalized to form a tube in the interior of the embryo, marking the start of gastrulation.


limb epidermis stratification

description: The pattern specification process that results in the subdivision of the epidermis of the limb in space to define a volume in which specific patterns of basal cell, spinous cell and granular cells will differentiate giving rise to the layers of the limb epidermis.


RNA stem-loop binding

description: Binding to a stem-loop in an RNA molecule. An RNA stem-loop is a secondary RNA structure consisting of a double-stranded RNA (dsRNA) stem and a terminal loop.


arachidonic acid binding

description: Binding to arachidonic acid, a straight chain fatty acid with 20 carbon atoms and four double bonds per molecule. Arachidonic acid is the all-Z-(5,8,11,14)-isomer.


name: negative regulation of programmed necrotic cell death

description: Any process that decreases the frequency, rate or extent of programmed necrotic cell death.


pyridoxal binding

description: Binding to pyridoxal, 3-hydroxy-5-(hydroxymethyl)-2-methylpyridine-4-carbaldehyde, a form of vitamin B6.


ubiquitin activating enzyme activity

description: Catalysis of the reaction: E1 + ubiquitin + ATP--> E1-ubiquitin + AMP + PPi, where the E1-ubiquitin linkage is a thioester bond between the C-terminal glycine of Ub and a sulfhydryl side group of an E1 cysteine residue. This is the first step in a cascade of reactions in which ubiquitin is ultimately added to a protein substrate.


name: single-species biofilm formation in or on host organism

description: A process in which microorganisms of the same species attach to and grow in or on a host species, and produce extracellular polymers that facilitate attachment and matrix formation, resulting in a change in the microorganisms' growth rate and gene transcription. The host is defined as the larger of the organisms involved in a symbiotic interaction.


name: gamma-aminobutyric acid biosynthetic process

description: The chemical reactions and pathways resulting in the formation of gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms.


name: positive regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation

description: Any process that activates or increases the frequency, rate or extent of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation.


abducens nerve formation

description: The process that gives rise to the abducens nerve. This process pertains to the initial formation of a structure from unspecified parts. The motor function of the abducens nerve is to contract the lateral rectus which results in abduction of the eye.


name: ergosteryl 3-beta-D-glucoside biosynthetic process

description: The chemical reactions and pathways resulting in the formation of ergosteryl 3-beta-D-glucoside.


description: Catalysis of the reaction: S-adenosyl-L-methionine + a 7-hydroxyisoflavone = S-adenosyl-L-homocysteine + a 7-methoxyisoflavone.


description: Catalysis of the reaction: (3Z)-phycoerythrobilin + oxidized ferredoxin = 15,16-dihydrobiliverdin + reduced ferredoxin.


name: versiconal hemiacetal acetate reductase activity

description: Catalysis of the reaction: versiconol acetate + NADP = versiconal hemiacetal acetate + NADPH.


response to purvalanol A

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a purvalanol A stimulus.


name: cytochrome c-heme linkage via heme-bis-L-cysteine

description: The linkage of cytochromes and other heme proteins to heme via heme-bis-L-cysteine.


sperm ejaculation

description: The expulsion of seminal fluid, thick white fluid containing spermatozoa, from the male genital tract.


mitochondrial inner membrane fusion

description: The membrane organization process that joins two mitochondrial inner membranes to form a single membrane.


name: signal transduction involved in filamentous growth

description: Relaying of environmental signals promoting filamentous growth.


heme B biosynthetic process

description: The chemical reactions and pathways resulting in the formation of heme B, a Fe(II) porphyrin complex readily isolated from the hemoglobin of beef blood, but also found in other proteins including other hemoglobins, myoglobins, cytochromes P-450, catalases, peroxidases as well as b type cytochromes.


extraocular skeletal muscle development

description: The process whose specific outcome is the progression of the extraocular skeletal muscle over time, from its formation to the mature structure. The extraocular muscle is derived from cranial mesoderm and controls eye movements. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle. An example of this process is found in Mus musculus.


antifungal peptide biosynthetic process

description: The chemical reactions and pathways resulting in the formation of an antifungal peptide.


name: atrial cardiac muscle cell to AV node cell communication by electrical coupling

description: The process that mediates signaling interactions between an atrial cardiomyocyte and an AV node cell by transfer of current between their adjacent cytoplasms via intercellular protein channels.


metanephric distal tubule morphogenesis

description: The process in which the anatomical structures of a metanephric distal tubule are generated and organized. The metanephric distal tubule is a metanephric nephron tubule that begins at the macula densa and extends to the metanephric connecting tubule.


4-hydroxymandelate oxidase activity

description: Catalysis of the reaction: (S)-4-hydroxymandelate + H+ + O2 = 4-hydroxybenzaldehyde + CO2 + H2O2.


description: Catalysis of the reaction: 4-(2-oxocyclohexyl)-2-hydroxy-buta-2,4-dienoate + H2O = 2-hydroxydec-2,4-diene-1,10-dioate + H+.


XTP diphosphatase activity

description: Catalysis of the reaction: XTP + H2O = XMP + H+ + diphosphate.


name: epithelial cell proliferation involved in lung morphogenesis

description: The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population that contributes to the shaping of the lung.


name: symbiont-mediated cAMP intoxication of host cell

description: The production by a symbiont of high levels of cyclic AMP in a host cell, impairing host cellular functions in multiple ways, including ATP depletion, interference with host intracellular signaling, cytoskeletal defects and apoptosis-related cell death. The host is defined as the larger of the organisms involved in a symbiotic interaction.


description: Catalysis of the reaction: 5-phospho-alpha-D-ribose 1-diphosphate + xanthine = (9-D-ribosylxanthine)-5'-phosphate + diphosphate.


NADPH-hemoprotein reductase activity

description: Catalysis of the reaction: NADPH + H+ + n oxidized hemoprotein = NADP+ + n reduced hemoprotein.


name: positive regulation of hair follicle development

description: Any process that activates or increases the frequency, rate or extent of hair follicle development.


histone H3 kinase activity

description: Catalysis of the transfer of a phosphate group to a histone H3.


description: Catalysis of the reaction: pyruvate + L-phenylalanine = phenylpyruvate + L-alanine.


name: metal incorporation into metallo-molybdopterin complex

description: The incorporation of a metal into a metallo-molybdopterin complex.


glycolipid binding

description: Binding to a glycolipid, any compound containing one or more monosaccharide residues bound by a glycosidic linkage to a hydrophobic group such as an acylglycerol, a sphingoid, a ceramide (N-acylsphingoid) or a prenyl phosphate.


name: negative regulation of high voltage-gated calcium channel activity in another organism

description: Any process in which an organism stops, prevents or reduces the frequency, rate or extent of the activity of a high voltage-gated calcium channel in another organism. A high voltage-gated channel is a channel whose open state is dependent on high voltage across the membrane in which it is embedded.


hypoglossal nerve development

description: The process whose specific outcome is the progression of the hypoglossal nerve over time, from its formation to the mature structure. This motor nerve innervates all the intrinsic and all but one of the extrinsic muscles of the tongue.


GTP-dependent protein kinase activity

description: GTP dependent catalysis of the reaction: ATP + a protein serine/threonine = ADP + protein serine/threonine phosphate.


peptidyl-serine decanoylation

description: The decanoylation of peptidyl-serine to form peptidyl-O3-decanoyl-L-serine, typical of the protein ghrelin.


sporopollenin biosynthetic process

description: The chemical reactions and pathways resulting in the formation of sporopollenin, a primary constituent of the pollen exine layer.


glutaconyl-CoA decarboxylase activity

description: Catalysis of the reaction: trans-glutaconyl-CoA + H+ = but-2-enoyl-CoA + CO2.


sneeze reflex

description: A reflex process that expels air forcibly from the mouth and nose in an explosive, spasmodic involuntary action resulting chiefly from irritation of the nasal mucous membrane.


kanamycin kinase activity

description: Catalysis of the reaction: ATP + kanamycin = ADP + 2 H+ + kanamycin 3'-phosphate.


name: RNA-protein covalent cross-linking via peptidyl-tyrosine

description: The formation of a covalent cross-link between RNA and a peptidyl-tyrosine residue by the formation of O4'-(phospho-5'-RNA)-L-tyrosine.


name: positive regulation of glial cell apoptotic process

description: Any process that activates or increases the frequency, rate, or extent of glial cell apoptotic process.


name: anterior lateral line neuromast deposition

description: The process in which a migrating neuromast primordium deposits clusters of undifferentiated cells (proneuromasts) along its migratory path in the developing anterior lateral line.


amyloplast organization

description: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an amyloplast. An amyloplast is a plastid whose main function is to synthesize and store starch.


Langerhans cell chemotaxis

description: The movement of a Langerhans cell in response to an external stimulus.


dorsal root ganglion development

description: The process whose specific outcome is the progression of a dorsal root ganglion over time, from its formation to the mature structure.


tooth mineralization

description: The process in which calcium salts are deposited into calcareous tooth structures such as dental enamel, dentin and cementum.


description: Catalysis of the reaction: CoA + 3-alpha,7-alpha-dihydroxy-5-beta-cholestanate + ATP = 3-alpha,7-alpha-dihydroxy-5-beta-cholestanoyl-CoA + diphosphate + AMP.


description: Catalysis of the reaction: (S)-(2-hydroxyacyl)glutathione + H2O = glutathione + a 2-hydroxy carboxylate.


name: melanin biosynthetic process from tyrosine

description: The chemical reactions and pathways resulting in the formation of melanin from other compounds, including tyrosine.


floor plate morphogenesis

description: The process in which the anatomical structure of the floor plate is generated and organized.


name: oxidized purine nucleobase lesion DNA N-glycosylase activity

description: Catalysis of the removal of oxidized purine bases by cleaving the N-C1' glycosidic bond between the oxidized purine and the deoxyribose sugar. The reaction involves the formation of a covalent enzyme-substrate intermediate. Release of the enzyme and free base by a beta-elimination or a beta, gamma-elimination mechanism results in the cleavage of the DNA backbone 3' of the apurinic (AP) site.


name: smoothened signaling pathway involved in dorsal/ventral neural tube patterning

description: The series of molecular signals generated as a consequence of activation of the transmembrane protein Smoothened contributing to the dorsal/ventral pattern of the neural tube.


name: polysaccharide transmembrane transporter activity

description: Enables the transfer of polysaccharides from one side of a membrane to the other. A polysaccharide is a polymer of many (typically more than 10) monosaccharide residues linked glycosidically.


D-fuconate dehydratase activity

description: Catalysis of the reaction: D-fuconate = 2-dehydro-3-deoxy-D-fuconate + H2O.


name: 5-ureido-4-imidazole carboxylate hydrolase activity

description: Catalysis of the reaction: 5-ureido-4-imidazole carboxylate + H2O = 5-amino-4-imidazole carboxylate + NH3 + CO2.


name: metanephric short descending thin limb development

description: The process whose specific outcome is the progression of the metanephric short descending thin limb over time, from its formation to the mature structure. The metanephric short descending thin limb is the descending thin limb of a short nephron in the metanephros that has a squamous epithelial morphology.


name: negative regulation of DNA damage response, signal transduction by p53 class mediator

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage.


cellular response to ecdysone

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ecdysone stimulus.


somatostatin receptor activity

description: Combining with somatostatin to initiate a change in cell activity. Somatostatin is a peptide hormone that regulates the endocrine system by signaling via G protein-coupled somatostatin receptors. Somatostatin has two active forms produced by proteolytic cleavage: a 14 amino acid peptide (SST-14) and a 28 amino acid peptide (SST-28).


name: dopamine neurotransmitter receptor activity

description: Combining with the neurotransmitter dopamine to initiate a change in cell activity.


virion attachment to host cell pilus

description: The process by which a virion attaches to a host cell by binding to a pilus on the host cell surface. Pili are retractile filaments that protrude from gram-negative bacteria. Filamentous viruses can attach to the pilus tip, whereas icosahedral viruses can attach to the pilus side.


name: positive regulation of telomerase RNA localization to Cajal body

description: Any process that activates or increases the frequency, rate or extent of telomerase RNA localization to Cajal body.


name: negative regulation of cellular response to hepatocyte growth factor stimulus

description: Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to hepatocyte growth factor stimulus.


name: regulation of thrombin-activated receptor signaling pathway

description: Any process that modulates the frequency, rate or extent of a thrombin-activated receptor signaling pathway activity. A thrombin receptor signaling pathway is the series of molecular signals generated as a consequence of a thrombin-activated receptor binding to one of its physiological ligands.


name: thyroid hormone transmembrane transporter activity

description: Enables the transfer of thyroid hormones from one side of a membrane to the other. Thyroid hormone are any of the compounds secreted by the thyroid gland, largely thyroxine and triiodothyronine.


name: negative regulation of morphogenesis of an epithelium

description: Any process that stops, prevents or reduces the frequency, rate or extent of morphogenesis of an epithelium.


name: protein import into peroxisome matrix, substrate release

description: The process by which the cargo protein is released into the peroxisomal matrix, following translocation across the membrane.


response to hydrogen sulfide

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen sulfide stimulus.


name: symbiont-mediated perturbation of host exit from mitosis

description: A process in which a virus interferes with the host cell completing the M phase of the cell cycle.


name: RNA splicing, via endonucleolytic cleavage and ligation

description: Splicing of RNA via recognition of the folded RNA structure that brings the 5' and 3' splice sites into proximity and cleavage of the RNA at both the 3' and 5' splice sites by an endonucleolytic mechanism, followed by ligation of the exons.


arylmalonate decarboxylase activity

description: Catalysis of the reaction: 2-aryl-2-methylmalonate + H+ = 2-arylpropionate + CO2.


name: carbon-oxygen lyase activity, acting on phosphates

description: Catalysis of the cleavage of a carbon-oxygen bond by elimination of a phosphate.


description: Catalysis of the reaction: CDP-diacylglycerol + H2O = a phosphatidate + CMP + 2 H+.


intracellular aspartate homeostasis

description: A homeostatic process involved in the maintenance of a steady state level of aspartate within a cell.


cellular response to endothelin

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an endothelin stimulus. Endothelin is any of three secretory vasoconstrictive peptides (endothelin-1, -2, -3).


name: inorganic diphosphate phosphatase activity

description: Catalysis of the reaction: diphosphate + H2O = H+ + 2 phosphate.


name: DNA strand elongation involved in cell cycle DNA replication

description: Any DNA strand elongation that is involved in cell cycle DNA replication.


peptidyl-aspartic acid modification

description: The modification of peptidyl-aspartic acid.


name: phagosome maturation involved in apoptotic cell clearance

description: A process that is carried out at the cellular level which results in the arrangement of constituent parts of a phagosome within a cell and contributes to apoptotic cell clearance. Phagosome maturation begins with endocytosis and formation of the early phagosome and ends with the formation of the hybrid organelle, the phagolysosome.


isocitrate metabolic process

description: The chemical reactions and pathways involving isocitrate, the anion of isocitric acid, 1-hydroxy-1,2,3-propanetricarboxylic acid. Isocitrate is an important intermediate in the TCA cycle and the glycoxylate cycle.


name: regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway

description: Any process that modulates the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to nitrosative stress.


name: positive regulation of vascular associated smooth muscle cell dedifferentiation

description: Any process that activates or increases the frequency, rate or extent of vascular smooth muscle cell dedifferentiation.


cellular response to osmotic stress

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.


name: zinc ion transmembrane transporter activity

description: Enables the transfer of zinc (Zn) ions from one side of a membrane to the other.


description: Catalysis of the reaction: nucleoside triphosphate + aminoglycoside = diphosphate + 2''-nucleotidylaminoglycoside.


name: effector-mediated perturbation of host innate immune response by symbiont

description: A process mediated by a molecule secreted by a symbiont that results in the modulation (either activation or suppression) of a host innate immune response. The host is defined as the larger of the organisms involved in a symbiotic interaction.


regulation of phospholipid efflux

description: Any process that modulates the frequency, rate or extent of phospholipid efflux.


protein lipoylation

description: The lipoylation of peptidyl-lysine to form peptidyl-N6-lipoyl-L-lysine.


description: Catalysis of the reaction: L-2-aminoadipate + L-cysteine + L-valine + 3 ATP + H2O = N-[(5S)-5-amino-5-carboxypentanoyl]-L-cysteinyl-D-valine + 3 AMP + 3 diphosphate + 6 H+.


response to dsDNA

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a double-stranded DNA stimulus.


S-methylmethionine metabolic process

description: The chemical reactions and pathways involving S-methyl-methionine (SMM). SMM can be converted to methionine by donating a methyl group to homocysteine, and concurrent operation of this reaction and that mediated by MMT sets up the SMM cycle.


name: negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator

description: Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator.


forebrain astrocyte differentiation

description: The process in which a relatively unspecialized cell acquires the specialized features of an astrocyte residing in the forebrain. An astrocyte is the most abundant type of glial cell. Astrocytes provide support for neurons and regulate the environment in which they function.


name: positive regulation of defense response to virus by host

description: Any host process that results in the promotion of antiviral immune response mechanisms, thereby limiting viral replication.


cytoplasm protein quality control

description: The chemical reactions and pathways resulting in the breakdown of misfolded proteins in the cytoplasm, which are either targeted to cytoplasmic proteasomes for degradation or protected by chaperones to shield thermosensitive proteins from degradation until conditions allow disaggregation and refolding.


hydrogen biosynthetic process

description: The chemical reactions and pathways resulting in the formation of H2 (dihydrogen).


name: regulation of microglial cell activation

description: Any process that modulates the frequency, rate or extent of microglial cell activation.


negative regulation of response to food

description: Any process that stops, prevents, or reduces the frequency, rate or extent of a response to a food stimulus.


name: diacylglycerol-dependent serine/threonine kinase activity

description: Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. This reaction requires diacylglycerol.


name: female germline ring canal formation, actin assembly

description: Recruitment and organization of actin filaments in female germline ring canals.


acyl-CoA biosynthetic process

description: The chemical reactions and pathways resulting in the formation of acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with an acyl group.


description: Catalysis of the reaction: 3',4',5'-trimethylmyricetin + S-adenosyl-L-methionine = 3,3',4',5'-tetramethylmyricetin + S-adenosyl-L-homocysteine + H+.


chorismate metabolic process

description: The chemical reactions and pathways involving chorismate, the anion of (3R-trans)-3-((1-carboxyethenyl)oxy)-4-hydroxy-1,5-cyclohexadiene-1-carboxylic acid.


regulation of peptide antigen transport

description: Any process that modulates the frequency, rate or extent of peptide antigen transport.


description: Catalysis of the reaction: O-phospho-L-threonine + H+ = (R)-1-aminopropan-2-yl phosphate + CO2.


O antigen biosynthetic process

description: The chemical reactions and pathways resulting in the formation of the O side chain of a lipopolysaccharide, which determines the antigenic specificity of the organism. It is made up of about 50 repeating units of a branched tetrasaccharide.


description: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: 2-keto-3-deoxygluconate(out) + H+(out) = 2-keto-3-deoxygluconate(in) + H+(in).


phosphoglycerate kinase activity

description: Catalysis of the reaction: 3-phospho-D-glycerate + ATP = 3-phospho-D-glyceroyl phosphate + ADP + H+.


cleistothecium development

description: The process whose specific outcome is the progression of the cleistothecium over time, from its formation to the mature structure. The cleistothecium is a closed sexual fruiting body that contains ascospores in linear asci, characteristic of some filamentous Ascomycete fungi such as members of the genera Aspergillus and Emericella.


UMP kinase activity

description: Catalysis of the reaction: ATP + UMP = ADP + UDP.


name: zinc:bicarbonate symporter activity

description: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: zinc(out) + HCO3-(out) = zinc(in) + HCO3-(in).


steroid 22-alpha hydroxylase activity

description: Catalysis of the reaction: 5-alpha-campestanaol + O2 = 6-deoxocathasterone + H2O.


T-helper cell differentiation

description: The process in which a relatively unspecialized thymocyte acquires specialized features of a T-helper cell.


de novo centriole assembly

description: Centriole assembly in which a centriole arises de novo, rather than by replication from an existing centriole. This process may occur via different mechanisms. Examples include the deuterosome pathway in multicilated epithelial animal cells and formation of centrioles during parthenogenesis in some insects.


name: positive regulation of lung alveolus development

description: Any process that activates or increases the frequency, rate or extent of lung alveolus development.


phenol 2-monooxygenase activity

description: Catalysis of the reaction: phenol + NADPH + H+ + O2 = catechol + NADP+ + H2O.


mammillotectal axonal tract development

description: The progression of the mammillotectal tract over time, from its formation to the mature structure. The mammillotectal tract is the collection of axons that connects the ventral diencephalon to the superior colliculus.


Wnt receptor activity

description: Combining with a Wnt protein and transmitting the signal across the plasma membrane to initiate a change in cell activity.


name: P-type potassium:proton transporter activity

description: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + H+(in) + K+(out) = ADP + phosphate + H+(out) + K+(in).


benzene catabolic process

description: The chemical reactions and pathways resulting in the breakdown of benzene.


closure of embryonic heart tube

description: Creation of the central hole of the embryonic heart tube by sealing the edges of an epithelial fold.


description: Catalysis of the reaction: a 1,2-diacyl-sn-glycero-3-phosphocholine + L-serine = 1,2-diacyl-sn-glycero-3-phospho-L-serine + choline.


vagus nerve morphogenesis

description: The process in which the anatomical structure of the vagus nerve is generated and organized. This nerve is primarily sensory but also has visceromotor components. It originates in the brain stem and controls many autonomic functions of the heart, lungs, stomach, pharynx, larynx, trachea, esophagus and other gastrointestinal tract components. It controls some motor functions such as speech. The sensory branches mediate sensation from the pharynx, larynx, thorax and abdomen; it also innervates taste buds in the epiglottis.


chitin binding

description: Binding to chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues.


name: negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway

description: Any process that stops, prevents or reduces the frequency, rate or extent of an adenylate cyclase-activating G protein-coupled receptor signaling pathway.


response to tumor cell

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a tumor cell.


name: regulation of ecdysone receptor signaling pathway

description: Any process that modulates the frequency, rate or extent of the activity of any ecdysone receptor signaling pathway.


pons reticulospinal tract morphogenesis

description: Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the pons towards target cells in the spinal cord.


response to leptomycin B

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leptomycin B stimulus.


name: proboscis morphogenesis, eye-antennal disc-derived

description: The process in which the anatomical structures of the proboscis that are derived from the eye-antennal disc are generated and organized.


description: The chemical reactions and pathways resulting in the breakdown of N(omega)-methyl-L-arginine.


name: W-molybdopterin cofactor catabolic process

description: The chemical reactions and pathways resulting in the breakdown of the W-molybdopterin cofactor, essential for the catalytic activity of some enzymes. The cofactor consists of a mononuclear tungsten ion (W) coordinated by one or two molybdopterin ligands.


cellular response to L-glutamine

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-glutamine stimulus.


geraniol kinase activity

description: Catalysis of the reaction: geraniol + nucleoside triphosphate = geranyl monophosphate + nucleoside diphosphate.


midbrain-hindbrain boundary initiation

description: The regionalization process that gives rise to the midbrain-hindbrain boundary. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate.


description: Catalysis of the reaction: 3-hydroxybenzoate + H+ + NADH + O2 = 2,5-dihydroxybenzoate + H2O + NAD+.


name: ventricular cardiac muscle cell membrane repolarization

description: The process in which ions are transported across the plasma membrane of a ventricular cardiac muscle cell such that the membrane potential changes in the repolarizing direction, toward the steady state potential. For example, the repolarization during an action potential is from a positive membrane potential towards a negative resting potential.


indole 2,3-dioxygenase activity

description: Catalysis of the reaction: indole + O2 = 2-formamidobenzaldehyde.


purine nucleoside binding

description: Binding to a purine nucleoside, a compound consisting of a purine base linked either to ribose or deoxyribose.


name: negative regulation of semaphorin-plexin signaling pathway

description: Any process that stops, prevents or reduces the frequency, rate or extent of semaphorin-plexin signaling pathway.


name: negative regulation of vascular associated smooth muscle cell dedifferentiation

description: Any process that stops, prevents or reduces the frequency, rate or extent of vascular smooth muscle cell dedifferentiation.


polyprenyltransferase activity

description: Catalysis of the transfer of multiple prenyl groups from one compound (donor) to another (acceptor).


L-arabitol metabolic process

description: The chemical reactions and pathways involving L-arabitol, the pentitol derived from arabinose or lyxose by reduction of the aldehyde group.


name: negative regulation of L-threonine import across plasma membrane

description: Any process that stops, prevents or reduces the frequency, rate or extent of L-threonine import into cell.


voluntary skeletal muscle contraction

description: A process in which force is generated within voluntary skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. In the voluntary skeletal muscle, the muscle contraction takes advantage of an ordered sarcomeric structure and it is under voluntary control. Voluntary skeletal muscle is skeletal muscle that is under conscious control.


decanoyltransferase activity

description: Catalysis of the transfer of a decanoyl (CH3-[CH2]8-CO-) group to an acceptor molecule.


name: 2-hydroxyglutarate dehydrogenase activity, forward reaction

description: Catalysis of the reaction: (S)-2-hydroxyglutarate + acceptor -> 2-oxoglutarate + reduced acceptor.


ADP metabolic process

description: The chemical reactions and pathways involving ADP, adenosine 5'-diphosphate.


name: negative regulation of high-density lipoprotein particle clearance

description: Any process that decreases the rate, frequency or extent of high-density lipoprotein particle clearance. High-density lipoprotein particle clearance is the process in which a high-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.


name: cytosine transmembrane transporter activity

description: Enables the transfer of cytosine, 4-amino-2-hydroxypyrimidine from one side of a membrane to the other.


name: regulation of tube length, open tracheal system

description: Ensuring that a tube in an open tracheal system is of the correct length.


name: postsynaptic neurotransmitter receptor activity

description: Neurotransmitter receptor activity occurring in the postsynaptic membrane during synaptic transmission.


name: determination of dorsal/ventral asymmetry

description: Determination of asymmetry from the dorsal to the ventral side; as, the dorsoventral axis.


name: symbiont-mediated activation of host inflammasome-mediated signal transduction

description: A process in which a symbiont subverts an inflammasome-mediated signal transduction pathway in the host organism by initiating, promoting, or enhancing its activation. The host is defined as the larger of the organisms involved in a symbiotic interaction.


ocellus photoreceptor cell development

description: Development of photoreceptors, sensory cells that react to the presence of light, found in the ocellus.


name: negative regulation of sinapate ester biosynthetic process

description: Any process that stops, prevents or reduces the frequency, rate or extent of sinapate ester biosynthesis.


name: regulation of demethylkotanin biosynthetic process

description: Any process that modulates the frequency, rate or extent of demethylkotanin biosynthetic process.


neuromast support cell differentiation

description: The process in which a relatively unspecialized cell acquires specialized features of a neuromast support cell. Support cells are non-sensory cells of the neuromast that extend between the sensory hair cells from the basement membrane to the apical surface; they are surrounded by mantle cells.


name: proline:sodium symporter activity

description: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: proline(out) + Na+(out) = proline(in) + Na+(in).


dITP diphosphatase activity

description: Catalysis of the reaction: dITP + H2O = dIMP + H+ + diphosphate.


name: glucan endo-1,4-beta-glucanase activity, C-3 substituted reducing group

description: Catalysis of the endohydrolysis of (1->4)-linkages in beta-D-glucans when the glucose residue whose reducing group is involved in the linkage to be hydrolysed is itself substituted at C-3.


name: negative regulation of formation of structure involved in a symbiotic process

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the progression of an organism from an initial condition to a later condition, occurring in, on or near the exterior of its host organism.


name: cellular response to jasmonic acid stimulus

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a jasmonic acid stimulus.


thyroid hormone catabolic process

description: The chemical reactions and pathways resulting in the breakdown of any of the compounds secreted by the thyroid gland, largely thyroxine and triiodothyronine.


embryonic dorsal fin morphogenesis

description: The process, occurring in the embryo, by which the anatomical structures of the dorsal fin are generated and organized. A dorsal fin is an unpaired medial fin on the dorsal aspect of a fish that provides lateral stability while swimming. Generally fish have one or two dorsal fins.


(13S)-vitexifolin A synthase activity

description: Catalysis of the reaction:9alpha-copalyl diphosphate + H2O = (13S)-vitexifolin A + diphosphate.


geraniol 10-hydroxylase activity

description: Catalysis of the reaction: geraniol + O2 + NADPH + H+ = (6E)-8-hydroxygeraniol + NADP + H2O.


cellular response to camptothecin

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a camptothecin stimulus.


description: Catalysis of the reaction: polyprenyl phosphate + UDP-D-glucose = polyprenylphosphate-glucose + UDP.


thiol S-methyltransferase activity

description: Catalysis of the reaction: S-adenosyl-L-methionine + a thiol = S-adenosyl-L-homocysteine + a thioether.


name: NAD-dependent histone H3K14 deacetylase activity

description: Catalysis of the reaction: histone H3 N6-acetyl-L-lysine (position 14) + H2O = histone H3 L-lysine (position 14) + acetate. This reaction requires the presence of NAD, and represents the removal of an acetyl group from lysine at position 14 of the histone H3 protein.


abscisic acid binding

description: Binding to abscisic acid, a plant hormone that regulates aspects of plant growth.


cellular response to ergosterol

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ergosterol stimulus.


PEP carboxykinase C4 photosynthesis

description: The process of C4 photosynthesis, as it occurs in plants in which the enzyme decarboxylating C4 acids in the bundle sheath is phosphoenolpyruvate carboxykinase (PEPCK).


cellular response to formaldehyde

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a formaldehyde stimulus.


glioblast division

description: The process resulting in the physical partitioning and separation of a glioblast into daughter cells.


alpha-1,4-glucan synthase activity

description: Catalysis of the reaction: RDP-glucose + [alpha-D-glucosyl-(1,4)]n = RDP + [alpha-D-glucosyl-(1,4)]n+1, where RDP is ADP or UDP.


ureter urothelium development

description: The process whose specific outcome is the progression of the urothelium of the ureter over time, from its formation to the mature structure. The urothelium is an epithelium that makes up the epithelial tube of the ureter.


name: sphingolipid biosynthesis involved in endoplasmic reticulum membrane organization

description: The chemical reactions and pathways resulting in the formation of sphingolipids that contributes to endoplasmic reticulum membrane organization.


name: negative regulation of determination of dorsal identity

description: Any process that stops, prevents, or reduces the frequency, rate or extent of determination of dorsal identity.


positive regulation of angiogenesis

description: Any process that activates or increases angiogenesis.


name: negative regulation of heme biosynthetic process

description: Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of heme.


name: platelet-derived growth factor receptor activity

description: Combining with platelet-derived growth factor receptor ligand and transmitting the signal across the plasma membrane to initiate a change in cell activity.


cellular response to amine stimulus

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amine stimulus. An amine is a compound formally derived from ammonia by replacing one, two or three hydrogen atoms by hydrocarbyl groups.


name: nitrate:proton symporter activity

description: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: nitrate(out) + H+(out) = nitrate(in) + H+(in).


presynaptic active zone assembly

description: The aggregation, arrangement and bonding together of a set of components to form a presynaptic active zone. The presynaptic active zone is a specialized region of the plasma membrane and cell cortex of a presynaptic neuron; encompasses a region of the plasma membrane where synaptic vesicles dock and fuse, and a specialized cortical cytoskeletal matrix.


name: iron incorporation into iron-sulfur cluster via tris-L-cysteinyl-L-serinyl tetrairon tetrasulfide

description: The incorporation of iron into a 4Fe-4S iron-sulfur cluster via tris-L-cysteinyl-L-serinyl tetrairon tetrasulfide.


name: positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation

description: Any process that activates or increases the frequency, rate or extent of CD8-positive, alpha-beta cytotoxic T cell extravasation.


alkyl hydroperoxide reductase activity

description: Catalysis of the reaction: octane hydroperoxide + NADH + H+ = H2O + NAD+ + 1-octanol.


name: parasexual reproduction with cellular fusion

description: A type of reproduction in which new individuals are produced from two individuals, with the fusion of two somatic cells.


name: organellar voltage-gated chloride channel activity

description: Enables the transmembrane transfer of a chloride ion by a voltage-gated channel. The membrane is an organellar membrane.


name: hydroperoxy icosatetraenoate dehydratase activity

description: A hydroperoxy icosatetraenoate = an oxoicosatetraenoate + H2O.


itaconyl-CoA hydratase activity

description: Catalysis of the reaction: citramalyl-CoA = itaconyl-CoA + H2O.


sperm incapacitation

description: The process in which the use of stored sperm from the first-mating male is inhibited by the seminal fluid of subsequently mating males.


adrenal cortex formation

description: The process that gives rise to the adrenal cortex. This process pertains to the initial formation of a structure from unspecified parts. The adrenogonadal primordium from which the adrenal cortex is formed derives from a condensation of coelomic epithelial cells (the urogenital ridge; the same structure from which gonads and kidney also originate).


regulation of cornification

description: Any process that modulates the frequency, rate or extent of cornification.


name: negative regulation of response to cytokine stimulus

description: Any process that decreases the rate, frequency, or extent of a response to cytokine stimulus.


post-embryonic dorsal fin morphogenesis

description: The process, occurring after embryonic development, by which the anatomical structures of the dorsal fin are generated and organized. A dorsal fin is an unpaired medial fin on the dorsal aspect of a fish that provides lateral stability while swimming. Generally fish have one or two dorsal fins.


sulfur amino acid catabolic process

description: The chemical reactions and pathways resulting in the breakdown of amino acids containing sulfur, comprising cysteine, methionine and selenocysteine.


amine dehydrogenase activity

description: Catalysis of the reaction: an aliphatic amine + an acceptor (A) + H2O = an aldehyde + a reduced acceptor (AH2) + NH4+.


stizolobate synthase activity

description: Catalysis of the reaction: 3,4-dihydroxy-L-phenylalanine + O2 = 4-(L-alanin-3-yl)-2-hydroxy-cis,cis-muconate 6-semialdehyde.


name: amyloid precursor protein metabolic process

description: The chemical reactions and pathways involving amyloid precursor protein (APP), the precursor of amyloid-beta, a glycoprotein associated with Alzheimer's disease.


name: sexual sporulation resulting in formation of a multicellular or syncytial spore

description: The formation of multicellular or syncytial spore via septations derived from meiosis. A multicellular or syncytial spore is a structure that can be used for dissemination, for survival of adverse conditions because of its heat and desiccation resistance, and/or for reproduction.


name: traversing start control point of mitotic cell cycle

description: A cell cycle process by which a cell commits to entering S phase via a positive feedback mechanism between the regulation of transcription and G1 CDK activity.


O-phosphoserine sulfhydrylase activity

description: Catalysis of the reaction: O-phospho-L-serine + hydrogen sulfide = L-cysteine + phosphate.


name: anterior lateral line nerve glial cell differentiation

description: The process in which a relatively unspecialized cell acquires specialized features of a glial cell in the anterior lateral line nerve.


Lugaro cell differentiation

description: The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature Lugaro cell. Differentiation includes the processes involved in commitment of a neuroblast to a Lugaro cell fate. A Lugaro cell is an inhibitory GABAergic interneuron found in the cerebellar cortex.


name: dissimilatory sulfite reductase activity

description: Catalysis of the reactions: [DsrC protein]-trisulfide + 3 H2O + NAD+ = [DsrC protein]-dithiol + 3 H+ + NADH + sulfite.


name: growth plate cartilage chondrocyte morphogenesis

description: The process in which the structures of a chondrocyte in the growth plate cartilage are generated and organized.


name: regulation of hepatic stellate cell proliferation

description: Any process that modulates the frequency, rate or extent of hepatic stellate cell proliferation.


quinolinate catabolic process

description: The chemical reactions and pathways resulting in the breakdown of quinolinate, the anion of quinolinic acid, also known as 2,3-pyridinedicarboxylic acid.


name: intracellular mRNA localization involved in anterior/posterior axis specification

description: Any process in which mRNA is transported to, or maintained in, a specific location within the oocyte and/or syncytial embryo that contributes to the specification of the anterior/posterior axis.


bioluminescence

description: The production of light by certain enzyme-catalyzed reactions in cells.


description: Catalysis of the reaction: 4-coumaroyl-CoA + agmatine = N-(4-guanidiniumylbutyl)-4-hydroxycinnamamide + CoA + H+.


name: mitochondrion-endoplasmic reticulum membrane tether activity

description: The binding activity of a molecule that brings together a mitochondrion and an ER membrane either via membrane lipid binding or by interacting with a mitochondrial outer membrane protein, to establish or maintain the localization of the mitochondrion.


name: 'de novo' GDP-L-fucose biosynthetic process

description: The chemical reactions and pathways resulting in the formation of GDP-L-fucose from GDP-D-mannose via GDP-4-dehydro-6-deoxy-D-mannose, requiring the functions of GDP-mannose 4,6-dehydratase (EC:4.2.1.47) and GDP-L-fucose synthase (EC:1.1.1.271).


name: positive regulation of hepatocyte growth factor receptor signaling pathway

description: Any process that activates or increases the frequency, rate or extent of hepatocyte growth factor receptor signaling pathway.


mammary gland formation

description: The process pertaining to the initial formation of the mammary gland from unspecified parts. The process begins with formation of the mammary line and ends when the solid mammary bud invades the primary mammary mesenchyme.


name: negative regulation of hematopoietic progenitor cell differentiation

description: Any process that stops, prevents or reduces the frequency, rate or extent of hematopoietic progenitor cell differentiation.


description: Catalysis of the reaction: NAD+ + propane-1,2-diol 1-phosphate = H+ + hydroxyacetone phosphate + NADH.


epistomal sclerite development

description: The process whose specific outcome is the progression of the epistomal sclerite over time, from its formation to the mature structure.


oxysterol binding

description: Binding to oxysterol, an oxidized form of cholesterol.


name: positive regulation of hepatic stellate cell activation

description: Any process that activates or increases the frequency, rate or extent of hepatic stellate cell activation.


regulation of cytolysis

description: Any process that modulates the frequency, rate or extent of the rupture of cell membranes and the loss of cytoplasm.


cellular response to lipoteichoic acid

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipoteichoic acid stimulus; lipoteichoic acid is a major component of the cell wall of gram-positive bacteria and typically consists of a chain of glycerol-phosphate repeating units linked to a glycolipid anchor.


name: agglutination involved in conjugation with mutual genetic exchange

description: The aggregation or adhesion of compatible mating types via complementary cell-cell interactions during conjugation without cellular fusion of a unicellular organism.


name: SREBP-SCAP complex retention in endoplasmic reticulum

description: Any process in which the SREBP-SCAP complex is maintained in the endoplasmic reticulum and prevented from moving elsewhere. The SREBP-SCAP complex is formed by the association of sterol regulatory element binding protein (SREBP) and SREBP-cleavage-activating protein (SCAP). In the absence of sterols, the SREBP-SCAP complex is packaged into COPII vesicles and travels to the Golgi apparatus to be processed. In the presence of sterols, the complex binds ER-resident proteins such as INSIG, which retain the complex in the ER.


name: symbiont-mediated disruption of host mucosa

description: The disruption of the host mucosa by a symbiont, leading to damage or temporary subversion of that tissue. The mucosa is a membrane that lines various cavities in the body of an organism and covers the surface of internal organs.


cardioblast cell fate specification

description: The process in which a cell becomes capable of differentiating autonomously into a cardioblast cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.


carbon fixation

description: A metabolic process in which carbon (usually derived from carbon dioxide) is incorporated into organic compounds (usually carbohydrates).


actin cortical patch assembly

description: Assembly of an actin cortical patch, a discrete actin-containing structure found at the plasma membrane of fungal cells.


name: negative regulation of response to calcium ion

description: Any process that stops, prevents or reduces the frequency, rate or extent of response to calcium ion.


name: negative regulation of erythrocyte aggregation

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of erythrocyte aggregation.


name: positive regulation of the force of heart contraction by epinephrine

description: The process in which the secretion of epinephrine into the bloodstream or released from nerve endings modulates the force of heart muscle contraction.


name: anterior/posterior pattern specification involved in ureteric bud development

description: The developmental process that results in the creation of defined areas or spaces within the ureteric bud along the anterior/posterior axis to which cells respond and eventually are instructed to differentiate.


response to decalin

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a decalin stimulus.


name: cytochrome P450 dependent 16beta-hydroxy-beta-amyrin epoxidase activity

description: Catalysis of the reaction: 16beta-hydroxy-beta-amyrin + O2 + H+ + NAD(P)H = 12,13beta-epoxy-16beta-hydroxy-beta-amyrin + H2O + NAD(P).


name: positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway

description: The series of molecular signals initiated by the binding of a vascular endothelial growth factor (VEGF) to its receptor on the surface of a cell, which activates or increases the frequency, rate or extent of endothelial cell chemotaxis.


name: positive regulation of C-C chemokine receptor CCR7 signaling pathway

description: Any process that activates or increases the frequency, rate or extent of C-C chemokine receptor CCR7 signaling pathway.


prothoracic disc development

description: Progression of the prothoracic disc over time, from its initial formation through to its metamorphosis to form the adult humerous and anterior spiracle.


FAD metabolic process

description: The chemical reactions and pathways involving FAD, the oxidized form of flavin adenine dinucleotide.


peptidyl-tyrosine dehydrogenation

description: The oxidation of the C alpha-C beta bond of peptidyl-tyrosine to form peptidyl-dehydrotyrosine coupled with cyclization of neighboring residues.


name: regulation of dopamine receptor signaling pathway

description: Any process that modulates the frequency, rate or extent of a dopamine receptor signaling pathway activity. A dopamine receptor signaling pathway is the series of molecular signals generated as a consequence of a dopamine receptor binding to one of its physiological ligands.


swim bladder formation

description: The process that gives rise to the swim bladder. This process pertains to the initial formation of a structure from unspecified parts. The swim bladder is used by some fishes to maintain buoyancy and may function in addition as a sound producing organ, a sound receptor, and a respiratory organ.


psychomotor behavior

description: The specific behavior of an organism that combines cognitive functions and physical movement. For example, driving a car, throwing a ball, or playing a musical instrument.


description: Catalysis of the reaction: D-arabinono-1,4-lactone + O2 = dehydro-D-arabinono-1,4-lactone + H2O2 + H+.


description: The series of molecular signals initiated by interleukin-18 binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.


name: IRES-dependent translational initiation of linear mRNA

description: The process where translation initiation recruits the 40S ribosomal subunits via an internal ribosome entry segment (IRES) before an AUG codon is encountered in an appropriate sequence context to initiate linear mRNA translation.


name: regulation of branching involved in salivary gland morphogenesis

description: Any process that modulates the rate, frequency, or extent of branching morphogenesis in the salivary gland epithelium.


name: trans-activation response element binding

description: Binding to a trans-activation response (TAR) element, a hairpin RNA structure located at the 5' end of all HIV-1 transcripts, and which is required for trans-activation of a viral promoter.


cellulose-polysulfatase activity

description: Catalysis of the hydrolysis of the 2- and 3-sulfate groups of the polysulfates of cellulose and charonin.


ultradian rhythm

description: The specific actions or reactions of an organism that recur with a regularity more frequent than every 24 hours.


name: protein-phosphocysteine-glucose phosphotransferase system transporter activity

description: Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + glucose(out) = protein cysteine + glucose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.


telomeric loop disassembly

description: The telomere maintenance process in which telomeric loops are disassembled to permit efficient telomere replication.


name: substantia propria of cornea development

description: The process whose specific outcome is the progression of a substantia propria of cornea over time, from its formation to the mature structure.


snoRNA guided rRNA 2'-O-methylation

description: The posttranscriptional addition of methyl groups to the 2'-oxygen atom of nucleotide residues in an rRNA molecule during ribosome biogenesis using a snoRNA guide that targets the position of methylation.


methylenediurea deaminase activity

description: Catalysis of the reaction: 2 H2O + methylenediurea = CO2 + 2 NH3 + N-hydroxymethylurea.


name: protein localization to actin filament bundle

description: A process in which a protein is transported to, or maintained in, the location of an actin filament bundle.


description: Catalysis of the reaction: 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1-carboxylate = (1R,6R)-2-succinyl-6-hydroxycyclohexa-2,4-diene-1-carboxylate + pyruvate.


name: voltage-gated calcium channel activity involved SA node cell action potential

description: Enables the transmembrane transfer of a calcium ion by a voltage-gated channel across the plasma membrane of an SA node cardiac muscle cell that contributes to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.


name: positive regulation of spore germination

description: Any process that activates or increases the frequency, rate or extent of spore germination.


name: endoribonuclease activity, cleaving miRNA-paired mRNA

description: Catalysis of the endonucleolytic cleavage of the mRNA in a double-stranded RNA molecule formed by the base pairing of an mRNA with an miRNA.


name: histone H3K56 acetyltransferase activity

description: Catalysis of the reaction: acetyl-CoA + histone H3 L-lysine (position 56) = CoA + histone H3 N6-acetyl-L-lysine (position 56).


induction of negative chemotaxis

description: Any process that initiates the directed movement of a motile cell or organism towards a lower concentration in a concentration gradient of a specific chemical.


name: cerebral cortex radially oriented cell migration

description: The migration of cells in the developing cerebral cortex in which cells move from the ventricular and/or subventricular zone toward the surface of the brain.


description: Catalysis of the reaction: 5,6-dihydroxy-3-methyl-5,6-dihydroquinolin-2(1H)-one + NAD+ = 5,6-dihydroxy-3-methyl-2-oxo-1,2-dihydroquinoline + H+ + NADH.


response to neutral pH

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a neutral pH (pH close to 7) stimulus. pH is a measure of the acidity or basicity of an aqueous solution.


description: Catalysis of the reaction: UDP-alpha-D-glucose + gypsogenate = gypsogenate-28-beta-D-glucoside + UDP.


positive gravitropism

description: The orientation of plant parts towards gravity.


name: (+)-pulegone reductase, (+)-isomenthone as substrate, activity

description: Catalysis of the reaction: (+)-isomenthone + NADP+ = (+)-pulegone + NADPH + H+.


chlorophyll binding

description: Binding to a chlorophyll; a compound of magnesium complexed in a porphyrin (tetrapyrrole) ring and which functions as a photosynthetic pigment.


alpha-beta T cell lineage commitment

description: The process in which a pro-T cell becomes committed to becoming an alpha-beta T cell.


name: high-density lipoprotein particle binding

description: Binding to high-density lipoprotein particle, a lipoprotein particle with a high density (typically 1.063-1.21 g/ml) and a diameter of 5-10 nm that contains APOAs and may contain APOCs and APOE.


rRNA primary transcript binding

description: Binding to an unprocessed ribosomal RNA transcript.


ferrichrome biosynthetic process

description: The chemical reactions and pathways resulting in the formation of a ferrichrome. Ferrichromes are any of a group of growth-promoting Fe(III) chelates formed by various genera of microfungi. They are homodetic cyclic hexapeptides made up of a tripeptide of glycine (or other small neutral amino acids) and a tripeptide of an N'acyl-N4-hydroxy-L-ornithine.


response to ethylene

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ethylene (ethene) stimulus.


name: regulation of spore-bearing organ development

description: Any process that modulates the frequency, rate or extent of spore-bearing organ development, a process in which hyphae grow into special aggregates called fruiting bodies that produce new spores.


N-formylglutamate deformylase activity

description: Catalysis of the reaction: N-formyl-L-glutamate + H2O = L-glutamate + formate.


name: negative regulation of mononuclear cell migration

description: Any process that decreases the rate, frequency or extent of mononuclear cell migration. Mononuclear cell migration is the movement of a mononuclear cell within or between different tissues and organs of the body.


menstruation

description: The cyclic, physiologic discharge through the vagina of blood and endometrial tissues from the nonpregnant uterus.


regulatory T cell apoptotic process

description: Any apoptotic process in a regulatory T cell.


name: phospholipid-hydroperoxide glutathione peroxidase activity

description: Catalysis of the reaction: a hydroperoxy polyunsaturated fatty acid + 2 glutathione = a hydroxy polyunsaturated fatty acid + glutathione disulfide + H2O.


description: Catalysis of the reaction: campest-4-en-3beta-ol + NAD = campest-4-en-3-one + NADH + H+.


posterior commissure morphogenesis

description: Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the midbrain towards target cells in the diencephalon.


spermidine dehydrogenase activity

description: Catalysis of the reaction: spermidine + acceptor + H2O = 1,3-diaminopropane + 4-aminobutanal + reduced acceptor.


name: regulation of late endosome to lysosome transport

description: Any process that modulates the frequency, rate or extent of late endosome to lysosome transport.


aspartate transamidation

description: The exchange of the amino group of aspartate, the anion derived from aspartic acid, for another amino group.


cellular detoxification of metal ion

description: Any process carried out at the cellular level that reduces or removes the toxicity of a metal ion.


name: cell adhesion involved in multi-species biofilm formation

description: The attachment of a cell to a solid substrate, via cell adhesion molecules, contributing to the formation of a biofilm composed of microorganisms of different species.


sinoatrial valve formation

description: The developmental process pertaining to the initial formation of the sinoatrial valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable.


multi-multicellular organism process

description: A multicellular organism process which involves another multicellular organism of the same or different species.


glucose oxidase activity

description: Catalysis of the reaction: beta-D-glucose + O2 = D-glucono-1,5-lactone + H2O2.


name: positive regulation of gonad development

description: Any process that activates or increases the frequency, rate or extent of gonad development.


description: Catalysis of the reaction: L-methionine + glyoxylate = 4-methylthio-2-oxobutanoate + glycine.


flower phyllotactic patterning

description: The radial pattern formation process that results in the formation of floral organ primordia around a central axis in a flower primordium.


name: selenium-containing prosthetic group metabolic process

description: The chemical reactions and pathways involving a prosthetic group that contains selenium, as in the selenium-dependent molybdenum hydroxylases. The selenium atom in the prosthetic group is required for enzymatic function but is labile to a variety of treatments.


cyanogenic glycoside metabolic process

description: The chemical reactions and pathways involving cyanogenic glycosides, any glycoside containing a cyano group that is released as hydrocyanic acid on acid hydrolysis; such compounds occur in the kernels of various fruits.


ectodermal cell differentiation

description: The process in which relatively unspecialized cells acquire specialized structural and/or functional features of an ectodermal cell. Differentiation includes the processes involved in commitment of a cell to a specific fate.


flavonoid catabolic process

description: The chemical reactions and pathways resulting in the breakdown of flavonoids, a group of phenolic derivatives containing a flavan skeleton.


lutein biosynthetic process

description: The chemical reactions and pathways resulting in the formation of lutein.


right lung morphogenesis

description: The process in which anatomical structures of the right lung are generated and organized.


name: positive regulation of cardioblast proliferation

description: Any process that activates or increases the frequency, rate or extent of cardioblast proliferation.


epithelial cell maturation

description: The developmental process, independent of morphogenetic (shape) change, that is required for an epithelial cell to attain its fully functional state. An epithelial cell is a cell usually found in a two-dimensional sheet with a free surface.


name: ethanol-acetate fermentation to butyrate and caproate

description: The anaerobic chemical reactions and pathways resulting in the breakdown of ethanol and acetate to butyrate and caproate, yielding energy in the form of ATP.


name: lysine biosynthetic process via alpha-aminoadipate and saccharopine

description: The chemical reactions and pathways resulting in the formation of lysine via the intermediates alpha-aminoadipic acid and saccharopine. This pathway is used by yeast and fungi to synthesize the essential amino acid L-lysine, and pathway intermediates are often incorporated into secondary metabolic processes. The pathway proceeds as follows: alpha-ketoglutarate is converted to homocitrate, which is metabolized to 3-carboxyhex-2-enedioate and then homoisocitrate. This is then decarboxylated to form alpha-ketoadipate, which is then converted to alpha-aminoadipate. This is then reduced to form alpha-aminoadipate 6-semialdehyde, which is metabolized to saccharopine and finally L-lysine.


protein propionyltransferase activity

description: Catalysis of the reaction: propionyl-CoA + lysine in peptide = CoA + N-propionyl-lysine-peptide.


sterol catabolic process

description: The chemical reactions and pathways resulting in the breakdown of sterols, steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule.


name: internal mammary gland bud epithelial cell differentiation

description: The process in which a relatively unspecialized epithelial cell of the mammary placode becomes an internal epithelial cell of the mammary gland bud. Internal cells are small and of irregular shape.


vitamin catabolic process

description: The chemical reactions and pathways resulting in the breakdown of a vitamin, one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body.


3-ethylmalate synthase activity

description: Catalysis of the reaction: butanoyl-CoA + glyoxylate + H2O = 3-ethylmalate + CoA + H+.


corticospinal neuron axon decussation

description: The process in which the migration of an axon growth cone of a pyramidal cell that is part of the corticospinal tract is directed to cross the midline to the contralateral side.


thyroxine 5-deiodinase activity

description: Catalysis of the reaction: 3,3',5'-triiodo-L-thyronine + iodide + A + H+ = L-thyroxine + AH2.


name: maintenance of protein localization to heterochromatin

description: A process in which a protein is maintained in a location in telomeric heterochromatin.


name: development of secondary male sexual characteristics

description: The process whose specific outcome is the progression of the secondary male sexual characteristics over time, from their formation to the mature structures. In male humans, these include growth of axillary, chest, and pubic hair, voice changes, and testicular/penile enlargement. Development occurs in response to sex hormone secretion.


dichloromethane dehalogenase activity

description: Catalysis of the reaction: dichloromethane + H2O = 2 chloride + formaldehyde + 2 H+.


name: SAGA complex localization to transcription regulatory region

description: Any process in which a SAGA complex is transported to, or maintained in, a specific location in the transcription regulatory region of a gene.


name: negative regulation of natural killer cell differentiation

description: Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer cell differentiation.


photosynthetic acclimation

description: A response to light intensity in which exposure to medium-intensity light results in increased tolerance to high-intensity light.


name: asparagine catabolic process via L-aspartate

description: The chemical reactions and pathways resulting in the breakdown of glutamate, via the intermediate L-aspartate.


name: N-terminal protein amino acid glucuronylation

description: The glucuronylation of the N-terminal amino acid of proteins.


name: embryonic process involved in female pregnancy

description: A reproductive process occurring in the embryo or fetus that allows the embryo or fetus to develop within the mother.


name: Spemann organizer formation at the dorsal lip of the blastopore

description: Formation of the specialized region at the dorsal lip of the blatopore of the embryo that acts as the main signaling center establishing the vertebrate body plan.


taste bud development

description: The progression of the taste bud over time, from its formation to the mature state. The taste bud is a specialized area of the tongue that contains taste receptors.


response to dinitrophenol

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dinitrophenol stimulus.


name: caffeoyl-CoA: alcohol caffeoyl transferase activity

description: Catalysis of the reaction: caffeoyl-CoA + a saturated primary alcohol = an alkyl caffeate + CoA.


name: regulation of skeletal muscle tissue development

description: Any process that modulates the frequency, rate or extent of skeletal muscle tissue development.


intracellular chloride ion homeostasis

description: A homeostatic process involved in the maintenance of a steady state level of chloride ions within a cell.


name: negative regulation of cell proliferation involved in compound eye morphogenesis

description: Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation involved in compound eye morphogenesis.


name: regulation of olefin biosynthetic process

description: Any process that modulates the frequency, rate or extent of olefin biosynthetic process.


chitin-based cuticle development

description: Synthesis and deposition of a chitin-based noncellular, hardened, or membranous secretion from an epithelial sheet. An example of this process is found in Drosophila melanogaster.


compound leaf morphogenesis

description: The leaf morphogenesis process that results in the shaping of a compound leaf. A compound leaf is a leaf having two or more distinct leaflets that are evident as such from early in development.


name: histone H3K37 methyltransferase activity

description: Catalysis of the reaction: S-adenosyl-L-methionine + histone H3 L-lysine (position 37) = S-adenosyl-L-homocysteine + histone H3 N6-methyl-L-lysine (position 37). This reaction is the addition of a methyl group to the lysine residue at position 37 of the histone H3 protein.


name: 2-oxoglutarate, L-arginine oxygenase (succinate-forming) activity

description: Catalysis of the reaction: L-argininium(1+) + 2-oxoglutarate + O2 = (3S)-3-hydroxy-L-arginine(1+) + succinate + carbon dioxide.


name: levan fructotransferase (DFA-IV-forming) activity

description: Catalysis of the reaction: beta-D-fructopyranosyl-(2->6)-[D-fructofuranosyl-(2->6)]n-D-fructofuranoside = beta-D-fructopyranosyl-(2->6)-[D-fructofuranosyl-(2->6)](n-1)-D-fructofuranoside + di-beta-D-fructofuranose 2,6':2',6-dianhydride. This reaction is the production of di-beta-D-fructofuranose 2,6':2',6-dianhydride (DFA IV) by successively eliminating the diminishing (2->6)-beta-D-fructan (levan) chain from the terminal D-fructosyl-D-fructosyl disaccharide.


vitelline membrane formation

description: Construction of the vitelline membrane portion of the egg shell, a rigid structure required to maintain the shape of the egg.


name: negative regulation of oospore formation

description: Any process that stops, prevents, or reduces the frequency, rate or extent of oospore formation, a process in which male and female gametangia develop and fuse to form a thick-walled resting spore of oomycetes.


Atg8-family conjugating enzyme activity

description: Isoenergetic transfer of an Atg8 family modifier from one protein to a phosphatidylethanolamine or phosphatidylserine on a membrane, via the reaction X-Atg8 + Y = Y-Atg8 + X.


lipoprotein amino acid oxidation

description: The modification of a lipoprotein by oxidation of one or more amino acids in the protein.


name: 9-cis-beta-carotene 9',10'-cleavage oxygenase activity

description: Catalysis of the reaction: 9-cis-beta-carotene + O2 = 9-cis-10'-apo-beta-carotenal + beta-ionone.


name: multivesicular body fusion to apical plasma membrane

description: The fusion of the membrane of a multivesicular body with the apical plasma membrane, resulting in release of exosomes from the cell.


response to UV-B

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-B radiation stimulus. UV-B radiation (UV-B light) spans the wavelengths 280 to 315 nm.


response to forskolin

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a forskolin stimulus.


name: ABC-type peptide antigen transporter activity

description: Catalysis of the reaction: peptide antigen(in) + ATP = peptide antigen(out) + ADP + phosphate.


tabersonine 16-hydroxylase activity

description: Catalysis of the reaction: H+ + NADPH + O2 + tabersonine = 16-hydroxytabersonine + H2O + NADP+.


regulation of cellular extravasation

description: Any process that modulates the frequency, rate, or extent of cellular extravasation.


cellular response to methylglyoxal

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylglyoxal stimulus. Methylglyoxal is a 2-oxoaldehyde derived from propanal.


name: branching involved in blood vessel morphogenesis

description: The process of coordinated growth and sprouting of blood vessels giving rise to the organized vascular system.


name: negative regulation of hair follicle cell proliferation

description: Any process that stops, prevents or reduces the rate or extent of hair follicle cell proliferation.


name: negative regulation of G protein-coupled receptor signaling pathway

description: Any process that stops, prevents, or reduces the frequency, rate or extent of G protein-coupled receptor signaling pathway.


diphenyl ether 1,2-dioxygenase activity

description: Catalysis of the reaction: diphenyl ether + NADH + O2 + H+ = phenol + catechol + NAD+.


serotonin binding

description: Binding to serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties.


name: positive regulation of neural retina development

description: Any process that increases the rate, frequency, or extent of neural retina development, the progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells.


description: Catalysis of the reaction: alkyl halide + H2O = alcohol + HCl. Substrates are 1,3(R),4,6(R)-tetrachloro-1,4-cyclohexadiene (forms 2,4,5-trichloro-2,5-cyclohexadiene-1-ol) and 2,4,5-trichloro-2,5-cyclohexadiene-1-ol (forms 2,5-dichloro-2,5-cyclohexadiene-1,4-diol).


name: establishment of protein localization to spindle pole body

description: The directed movement of a protein to a specific location at the spindle pole body.


L-glutamine biosynthetic process

description: The chemical reactions and pathways resulting in the formation of L-glutamine.


formin-nucleated actin cable assembly

description: The aggregation, arrangement and bonding together of a set of components to form a formin-nucleated actin cable. A formin-nucleated actin cable is an actin filament bundle that consists of short filaments organized into bundles of uniform polarity, and is nucleated by formins.


ADP-D-ribose binding

description: Binding to ADP-D-ribose, an ADP-aldose having ribose as the aldose fragment.


name: negative regulation of adipose tissue development

description: Any process that stops, prevents or reduces the frequency, rate or extent of adipose tissue development.


benzoyl acetate-CoA ligase activity

description: Catalysis of the reaction: 3-oxo-3-phenylpropionate + CoA + ATP = AMP + diphosphate + benzoyl acetyl-CoA.


name: transcription elongation factor activity

description: A molecular function that stimulates the elongation properties of the RNA polymerase during the elongation phase of transcription. A subclass of transcription elongation factors enable the transition from transcription initiation to elongation, while another class rescue stalled RNA polymerases.


name: negative regulation of cellodextrin catabolic process

description: Any process that stops, prevents or reduces the frequency, rate or extent of cellodextrin catabolic process.


name: positive regulation of sporangium development

description: Any process that activates, maintains or increases the frequency, rate or extent of sporangium development, a process that leads to the formation of sporangium, a single-celled or many-celled structure in which spores are produced, as in fungi, algae, mosses, and ferns, gymnosperms, angiosperms.


name: epithelial cell morphogenesis involved in gastrulation

description: The change in form that occurs when an epithelial cell progresses from it initial formation to its mature state, contributing to the process of gastrulation.


description: Catalysis of the reaction: N-acetyl-beta-D-galactosaminyl-(1,4)-beta-D-glucuronosyl-proteoglycan + UDP-alpha-D-glucuronate = beta-D-glucuronosyl-(1,3)-N-acetyl-beta-D-galactosaminyl-(1,4)-beta-D-glucuronosyl-proteoglycan + UDP.


response to vitamin B1

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin B1 stimulus.


basidium development

description: The process that leads to the development of basidium, a small, specialized club-shaped structure typically bearing four basidiospores at the tips of minute projections. The basidium is unique to Basidiomycetes and distinguishes them from other kinds of fungi.


name: establishment of planar polarity of larval imaginal disc epithelium

description: Coordinated organization of groups of cells in the plane of a larval imaginal disc epithelium, such that they all orient to similar coordinates.


name: positive regulation of long-day photoperiodism, flowering

description: Any process that activates, maintains or increases long-day photoperiodism, where the response associated with the photoperiodism is flowering. Flowering is defined by the switch from the vegetative to the reproductive phase.


circadian temperature homeostasis

description: Any homeostatic process in which an organism modulates its internal body temperature at different values with a regularity of approximately 24 hours.


name: establishment or maintenance of microtubule cytoskeleton polarity

description: Any cellular process that results in the specification, formation or maintenance of polarized microtubule-based cytoskeletal structures.


name: class II DNA-(apurinic or apyrimidinic site) endonuclease activity

description: Catalysis of the hydrolysis of ester linkages immediately 5' to an apurinic/apyrimidinic (AP; also called abasic) site within a deoxyribonucleic acid molecule by creating internal breaks, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.


microsporocyte differentiation

description: The process aimed at the progression of a microsporocyte cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. A microsporocyte is a diploid (2n) cell that undergoes meiosis and forms four haploid (1n) microspores; also called microspore mother cell and, in seed plants, pollen mother cell.


NLRP3 inflammasome complex assembly

description: The aggregation, arrangement and bonding together of a set of components to form the NLRP3 inflammasome complex, occurring at the level of an individual cell.


cellular response to oxidopamine

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxidopamine stimulus.


name: regulation of cumulus cell differentiation

description: Any process that modulates the frequency, rate or extent of ovarian cumulus cell differentiation.


diestrus

description: The estrous cycle phase which is a period of sexual quiescence and represents the phase of the mature corpus luteum.


pyruvate metabolic process

description: The chemical reactions and pathways involving pyruvate, 2-oxopropanoate.


compound eye photoreceptor development

description: The process whose specific outcome is the progression of a light-responsive receptor in the compound eye over time, from its formation to the mature structure.


description: Catalysis of the reaction: UDP-glucose + gibberellin = UDP + gibberellin 2-O-beta-D-glucoside.


name: purine ribonucleoside triphosphate binding

description: Binding to a purine ribonucleoside triphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with triphosphate on the sugar.


mRNA dihydrouridine synthase activity

description: Catalysis of the reaction: mRNA-uracil + NAD(P)+ = mRNA-dihydrouridine + NAD(P)H+ + H+.


pollen development

description: The process whose specific outcome is the progression of the pollen grain over time, from its formation to the mature structure. The process begins with the meiosis of the microsporocyte to form four haploid microspores. The nucleus of each microspore then divides by mitosis to form a two-celled organism, the pollen grain, that contains a tube cell as well as a smaller generative cell. The pollen grain is surrounded by an elaborate cell wall. In some species, the generative cell immediately divides again to give a pair of sperm cells. In most flowering plants, however this division takes place later, in the tube that develops when a pollen grain germinates.


ganglion structural organization

description: The process that contributes to creating the structural organization of a ganglion. This process pertains to the physical shaping of a rudimentary structure.


taurine dioxygenase activity

description: Catalysis of the reaction: 2-oxoglutarate + O2 + taurine = aminoacetaldehyde + CO2 + succinate + sulfite.


name: skeletal muscle satellite cell activation

description: The change of a skeletal muscle satellite cell from a mitotically quiescent to a mitotically active state following exposure to some activating factor such as a cellular or soluble ligand. In adult muscle, satellite cells become activated to divide and differentiate in response to muscle damage.


plant-type cell wall organization

description: A process that results in the assembly and arrangement of constituent parts of the cellulose and pectin-containing cell wall, or in the disassembly of the cellulose and pectin-containing cell wall. This process is carried out at the cellular level. An example of this process is found in Arabidopsis thaliana.


maintenance of vesicle location

description: Any process in which a vesicle is maintained in a specific location within a cell and prevented from moving elsewhere.


name: negative regulation of myotube differentiation

description: Any process that decreases the frequency, rate or extent of myotube differentiation. Myotube differentiation is the process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse.


karyogamy

description: The creation of a single nucleus from multiple nuclei as a result of fusing the lipid bilayers that surround each nuclei.


amine biosynthetic process

description: The chemical reactions and pathways resulting in the formation of any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom.


name: regulation of gluconate transmembrane transport

description: Any process that modulates the frequency, rate or extent of the directed movement of a gluconate across a membrane by means of some agent such as a transporter or pore.


name: plasmacytoid dendritic cell cytokine production

description: Any process that contributes to cytokine production by a plasmacytoid dendritic cell.


name: protein N-linked glucosylation via asparagine

description: A process of protein N-linked glycosylation via asparagine in which glucose is added to the N4 of asparagine, forming an (S)-2-amino-4-(D-glucopyranosyl)amino-4-oxobutanoic acid residue.


box C/D sno(s)RNA metabolic process

description: The chemical reactions and pathways involving box C/D type small nucleolar RNA.


name: 4-methylumbelliferyl glucoside 6'-O-malonyltransferase activity

description: Catalysis of the reaction: 4-methylumbelliferyl glucoside + malonyl-CoA = 4-methylumbelliferone 6'-O-malonylglucoside + coenzyme A.


name: D-alanine [D-alanyl carrier protein] ligase activity

description: Catalysis of the ATP-dependent activation of D-alanine and its transfer as a thiol ester to the phosphopantheinyl prosthetic group of a D-alanyl carrier protein, according to the reaction: ATP + D-alanine + a [D-alaninyl carrier protein] = a D-alanyl-[D-alanyl carrier protein] + AMP + diphosphate.


Ran protein signal transduction

description: An intracellular signaling cassette in which a small monomeric GTPase of the Ran subfamily relays a signal.


name: membrane depolarization during action potential

description: The process in which membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential.


name: regulation of cilium movement involved in cell motility

description: Any process that modulates the rate frequency or extent of cilium movement involved in ciliary motility.


name: peptidyl-allysine oxidation to 2-aminoadipic acid

description: The oxidation of allysine to 2-aminoadipic acid.


description: Catalysis of the reaction: (3S,4R)-3,4-dihydrophenanthrene-3,4-diol + NAD+ = H+ + NADH + phenanthrene-3,4-diol.


name: regulation of MyD88-dependent toll-like receptor signaling pathway

description: Any process that modulates the frequency, rate, or extent of MyD88-dependent toll-like receptor signaling pathway.


auditory receptor cell fate commitment

description: The process in which the cellular identity of auditory hair cells is acquired and determined.


holo-citrate lyase synthase activity

description: Catalysis of the reaction: apo-citrate lyase + 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA = diphosphate + holo-citrate lyase.


response to parasitic plant

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a parasitic plant.


vagina development

description: The reproductive developmental process whose specific outcome is the progression of the vagina over time, from its formation to the mature structure.


sulfolipid metabolic process

description: The chemical reactions and pathways involving sulfolipids, any compound containing a sulfonic acid residue joined by a carbon-sulfur bond to a lipid.


lovastatin nonaketide synthase activity

description: Catalysis of the reaction: S-adenosyl-L-methionine(1+) + acetyl-CoA + 18 H+ + 8 malonyl-CoA + 11 NADPH = S-adenosyl-L-homocysteine + 8 CO2 + 9 CoA + dihydromonacolin L + 6 H2O + 11 NADP+.


name: negative regulation of choline O-acetyltransferase activity

description: Any process that stops, prevents or reduces the frequency, rate or extent of choline O-acetyltransferase activity.


name: linalyl 6-O-alpha-L-arabinopyranosyl-beta-D-glucopyranoside glucosidase (Yabukita) activity

description: Catalysis of the reaction: linalyl 6-O-alpha-L-arabinopyranosyl- beta-D-glucopyranoside + H2O = vicianose + linalool.


name: negative regulation of emodin biosynthetic process

description: Any process that stops, prevents or reduces the frequency, rate or extent of emodin biosynthetic process.


name: fosmidomycin transmembrane transporter activity

description: Enables the transfer of fosmidomycin, a phosphonic acid derivative with potent activity against Gram-negative organisms, from one side of a membrane to the other.


description: Catalysis of the reaction: cis-4-(2-(3-hydroxy)-thionaphthenyl)-2-oxo-3-butenoate = trans-4-(2-(3-hydroxy)-thionaphthenyl)-2-oxo-3-butenoate.


name: positive regulation of humoral immune response

description: Any process that activates or increases the frequency, rate, or extent of a humoral immune response.


description: Catalysis of the reaction: oxidized glutathione + CoA = reduced glutathione + CoA-glutathione.


deoxyribose-phosphate aldolase activity

description: Catalysis of the reaction: 2-deoxy-D-ribose 5-phosphate = D-glyceraldehyde 3-phosphate + acetaldehyde.


name: regulation of embryonic skeletal joint development

description: Any process that modulates the frequency, rate or extent of embryonic skeletal joint development.


name: positive regulation of urine volume by pressure natriuresis

description: An increase in the amount of urine excreted over a unit of time, as a result of pressure natriuresis.


regulation of lung alveolus development

description: Any process that modulates the frequency, rate or extent of lung alveolus development.


name: response to pheromone regulating conjugation with mutual genetic exchange

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pheromone stimulus regulating the process of conjugation without cellular fusion.


name: sexual sporulation resulting in formation of a cellular spore

description: The formation of spores derived from the products of meiosis. A cellular spore is a cell form that can be used for dissemination, for survival of adverse conditions because of its heat and desiccation resistance, and/or for reproduction.


name: regulation of growth of unicellular organism as a thread of attached cells

description: Any process that modulates the frequency, rate or extent of the process in which cells remain attached after division and form thread-like filaments that may penetrate into a solid growth medium.


name: L-phenylalanine biosynthetic process from chorismate via phenylpyruvate

description: The chemical reactions and pathways resulting in the formation of L-phenylalanine from other compounds, including chorismate, via the intermediate phenylpyruvate.


name: regulation of dopamine uptake involved in synaptic transmission

description: Any process that modulates the frequency, rate or extent of the directed movement of the catecholamine neurotransmitter dopamine into a cell.


protein localization to T-tubule

description: A process in which a protein is transported to, or maintained in, the T-tubule. The T-tubule is an invagination of the plasma membrane of a muscle cell that extends inward from the cell surface around each myofibril.