response to brassinosteroid

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a brassinosteroid stimulus.


name: regulation protein catabolic process at presynapse

category: biolink:BiologicalProcess biolink:Occurrent biolink:OntologyClass biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein at the presynapse.


bacteriochlorophyll binding

category: biolink:MolecularActivity biolink:Occurrent biolink:OntologyClass biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: Binding to bacteriochlorophyll, a form of chlorophyll found in photosynthetic bacteria, such as the purple and green bacteria. There are several types, designated a to g. Bacteriochlorophyll a and bacteriochlorophyll b are structurally similar to the chlorophyll a and chlorophyll b found in plants.


name: pouch outgrowth involved in semicircular canal formation

description: The morphogenetic process in which an epithelial sheet bends along a linear axis and gives rise to a pouch that will form a semicircular canal.


ensheathment of neuronal cell bodies

description: The process in which satellite glial cells isolate neuronal cell bodies.


name: negative regulation of transporter activity

description: Any process that stops or reduces the activity of a transporter.


name: establishment of body hair planar orientation

description: Orientation of body hairs, projections from the surface of an organism, such that the hairs all point in a uniform direction along the surface.


interleukin-33 receptor activity

description: Combining with interleukin-33 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


L-lysine 6-oxidase activity

description: Catalysis of the reaction: L-lysine + H2O + O2 = allysine + H2O2 + NH4.


name: GDP-mannose biosynthetic process from mannose

description: The chemical reactions and pathways resulting in the formation of GDP-mannose from mannose.


cellular response to interleukin-17

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-17 stimulus.


leucoanthocyanidin reductase activity

description: Catalysis of the reaction: (2R,3S)-catechin + NADP+ + H2O = 2,3-trans-3,4-cis-leucocyanidin + NADPH + H+.


name: double-strand break repair via single-strand annealing, removal of nonhomologous ends

description: During DSBR via single-strand annealing, the removal of nonhomologous sequences at the broken 3' single-strand DNA end before DNA repair synthesis can occur.


sno(s)RNA catabolic process

description: The chemical reactions and pathways resulting in the breakdown of snoRNA, small nucleolar RNA, any of a class of small RNAs that are associated with the eukaryotic nucleus as components of small nucleolar ribonucleoproteins.


name: killing by virus of host cell by post-segregational killing

description: The process by which a virus causes the death of daughter cells which do not contain its genes after host cell division, by a mechanism of post-segregational killing (PSK). The extrachromosomal viral DNA consist of two genes; the product of the second is long lived and toxic, while the product of the first is short lived and antagonizes the lethal action of the toxin. Daughter cells that do not contain the viral extrachromosomal element are killed by the long lived toxin, while daughter cells that do contain the viral extrachromosomal element are protected by the action of the short lived antitoxin it encodes.


description: The chemical reactions and pathways resulting in the formation of the exopolysaccharide galactosaminogalactan. GAG is a heteropolysaccharide composed of alpha-1,4 linked galactose, N-acetyl galactosamine (GalNAc) and galactosamine (GalN).


name: regulation of L-glutamine import across plasma membrane

description: Any process that modulates the frequency, rate or extent of L-glutamine import into cell.


choline-sulfatase activity

description: Catalysis of the reaction: choline sulfate + H2O = choline + H+ + sulfate.


UDP-rhamnose metabolic process

description: The chemical reactions and pathways involving UDP-L-rhamnose, a substance composed of rhamnose in glycosidic linkage with uridine diphosphate.


name: regulation of Schwann cell differentiation

description: Any process that modulates the frequency, rate or extent of Schwann cell differentiation.


name: 6-phosphoglucan, water dikinase activity

description: Catalysis of the reaction: n ATP + n H2O + a 6-phosphogluco-maltodextrin = n AMP + n hydrogenphosphate + a poly-6-phosphogluco-maltodextrin.


name: TRAIL death-inducing signaling complex assembly

description: The aggregation, arrangement and bonding together of a set of components to form a TRAIL death-inducing signaling complex.


sn-glycerol 3-phosphate binding

description: Binding to sn-glycerol 3-phosphate.


aminoacylase activity

description: Catalysis of the reaction: an N-acyl-L-amino acid + H2O = a carboxylate + an L-amino acid.


fatty acid homeostasis

description: Any process involved in the maintenance of an internal steady state of fatty acid within an organism or cell.


name: symbiont-mediated evasion of host innate immune response

description: A process by which a symbiont avoids recognition by host's innate immune response by altering, concealing or destroying a conserved symbiont molecule recognized by the host. The host is defined as the larger of the organisms involved in a symbiotic interaction.


response to Aroclor 1254

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an Aroclor 1254 stimulus.


regulation of ascus development

description: Any process that modulates the frequency, rate or extent of ascus development, a process that leads to the formation of basidium, a sac-like structure produced by fungi of the phylum Ascomycota (sac fungi) in which sexually produced spores (ascospores), usually four or eight in number, are formed.


name: positive regulation of border follicle cell migration

description: Any process that activates or increases the frequency, rate or extent of border follicle cell migration.


name: negative regulation of steroid metabolic process

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving steroids.


name: negative regulation of horizontal cell localization

description: Any process that stops, prevents or reduces the frequency, rate or extent of horizontal cell localization.


name: positive regulation of aortic smooth muscle cell differentiation

description: Any process that activates or increases the frequency, rate or extent of aortic smooth muscle cell differentiation.


myeloid dendritic cell chemotaxis

description: The movement of a myeloid dendritic cell in response to an external stimulus.


lupeol 28-monooxygenase activity

description: Catalysis of the reaction: lupeol + NADPH(4-) + O2 + H+ = betulin + NADP(3-) + H2O.


name: shikimate 3-dehydrogenase (NADP+) activity

description: Catalysis of the reaction: shikimate + NADP+ = 3-dehydroshikimate + NADPH + H+.


10-oxogeraniol oxidoreductase activity

description: Catalysis of the reaction: (6E)-8-oxogeraniol + NADP = (6E)-8-oxogeranial + NADPH + H+.


structural constituent of egg chorion

description: The action of a molecule that contributes to the structural integrity of an egg chorion. An example of this is found in Drosophila melanogaster.


description: Catalysis of the reaction: zeaxanthin + 2 NADH + 2 H+ + 2 O2 = nostoxanthin + 2 NAD + 2 H2O.


name: negative regulation of hormone metabolic process

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving any hormone.


name: lymph gland plasmatocyte differentiation

description: The process in which a relatively unspecialized larval lymph gland-derived hemocyte precursor cell acquires the specialized features of the phagocytic blood-cell type, the plasmatocyte.


name: negative regulation of mesodermal cell fate specification

description: Any process that stops, prevents, or reduces the frequency, rate or extent of mesoderm cell fate specification.


name: regulation of ER to Golgi vesicle-mediated transport

description: Any process that modulates the rate, frequency, or extent of ER to Golgi vesicle-mediated transport, the directed movement of substances from the endoplasmic reticulum (ER) to the Golgi, mediated by COP II vesicles. Small COP II coated vesicles form from the ER and then fuse directly with the cis-Golgi. Larger structures are transported along microtubules to the cis-Golgi.


dirigent protein activity

description: Catalysis of the reaction: 2 H+ + 2 coniferol + O2 = (+)-pinoresinol + 2 H2O.


violaxanthin de-epoxidase activity

description: Catalysis of the reaction: violaxanthin + 2 ascorbate = zeaxanthin + 2 dehydroascorbate + 2 H2O; and antheraxanthin + ascorbate = zeaxanthin + dehydroascorbate + H2O.


pigment accumulation

description: The aggregation of coloring matter in a particular location in an organism, tissue or cell, occurring in response to some external stimulus.


low-affinity IgE receptor activity

description: Combining with low affinity with an immunoglobulin of the IgE isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


name: negative regulation of cell differentiation involved in phenotypic switching

description: Any process that stops, prevents or reduces the frequency, rate or extent of cell differentiation involved in phenotypic switching.


protein retention in Golgi apparatus

description: The retention of proteins within the Golgi apparatus. Golgi-localized carbohydrate-modifying enzymes have a short N-terminal domain that faces the cytosol, a single transmembrane alpha helix, and a large C-terminal domain that faces the Golgi lumen and that contains the catalytic site. How the membrane-spanning alpha helix in a Golgi enzyme causes its localization and prevents its movement to the plasma membrane is not known.


fourth ventricle development

description: The process whose specific outcome is the progression of the fourth ventricle over time, from its formation to the mature structure. The fourth ventricle is an irregularly shaped cavity in the rhombencephalon, between the medulla oblongata, the pons, and the isthmus in front, and the cerebellum behind. It is continuous with the central canal of the cord below and with the cerebral aqueduct above, and through its lateral and median apertures it communicates with the subarachnoid space.


L-ascorbate oxidase activity

description: Catalysis of the reaction: 4 L-ascorbate + O2 = 4 monodehydroascorbate + 2 H2O.


RNA strand-exchange activity

description: Facilitates the displacement of one strand of an RNA-RNA duplex and its replacement with a different strand of higher complementarity.


name: choline biosynthetic process via CDP-choline

description: The chemical reactions and pathways resulting in the formation of choline (2-hydroxyethyltrimethylammonium), via the intermediate CDP-choline.


superior raphe nucleus development

description: The process whose specific outcome is the progression of the superior raphe nucleus over time, from its formation to the mature structure.


creatinine catabolic process to formate

description: The chemical reactions and pathways resulting in the breakdown of creatinine into other compounds, including formate.


name: 4-hydroxybenzoate amino acid synthetase activity

description: Catalysis of the reaction: 4-hydroxybenzoate + ATP + amino acid = 4-hydroxybenzoyl amino acid conjugate + AMP + diphosphate.


name: S-(hydroxymethyl)glutathione dehydrogenase (NADP+) activity

description: Catalysis of the reaction: S-(hydroxymethyl)glutathione + NADP+ = S-formylglutathione + NADPH + H+.


name: positive regulation of Schwann cell migration

description: Any process that activates or increases the frequency, rate or extent of Schwann cell migration.


ventral midline development

description: The process whose specific outcome is the progression of the ventral midline over time, from its formation to the mature structure. In protostomes (such as insects, snails and worms) as well as deuterostomes (vertebrates), the midline is an embryonic region that functions in patterning of the adjacent nervous tissue. The ventral midline in insects is a cell population extending along the ventral surface of the embryo and is the region from which cells detach to form the ventrally located nerve cords. In vertebrates, the midline is originally located dorsally. During development, it folds inwards and becomes the ventral part of the dorsally located neural tube and is then called the ventral midline, or floor plate.


name: negative regulation of synoviocyte proliferation

description: Any process that stops, prevents or reduces the frequency, rate or extent of synoviocyte proliferation.


5S rRNA binding

description: Binding to a 5S ribosomal RNA, the smallest RNA constituent of a ribosome.


name: ventricular compact myocardium morphogenesis

description: The process in which the anatomical structures of the compact cardiac ventricle muscle are generated and organized.


name: regulation of developmental pigmentation

description: Any process that modulates the frequency, rate or extent of the developmental process that results in the deposition of coloring matter in an organism.


name: response to diacyl bacterial lipopeptide

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diacylated bacterial lipopeptide stimulus.


name: flavin-containing compound metabolic process

description: The chemical reactions and pathways involving a flavin, any derivative of the dimethylisoalloxazine (7,8-dimethylbenzo[g]pteridine-2,4(3H,10H)-dione) skeleton, with a substituent on the 10 position.


name: high-affinity zinc transmembrane transporter activity

description: Enables the transfer of zinc ions (Zn2+) from one side of a membrane to the other, probably powered by proton motive force. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.


name: shikimate transmembrane transporter activity

description: Enables the transfer of shikimate from one side of a membrane to the other. Shikimate is an important intermediate in the biosynthesis of aromatic amino acids.


name: mesonephric glomerular parietal epithelial cell fate commitment

description: The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesonephric glomerular parietal epithelial cell. Mesonephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. These cells may also give rise to podocytes.


fruit ripening

description: An developmental maturation process that has as participant a fruit. Ripening causes changes in one or more characteristics of a fruit (color, aroma, flavor, texture, hardness, cell wall structure) and may make it more attractive to animals and aid in seed dispersal.


response to photoperiod, blue light

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the detection of a blue light photoperiod stimulus. Blue light is electromagnetic radiation with a wavelength of between 440 and 500nm.


halogen metabolic process

description: The chemical reactions and pathways involving any halogen, elements of Group VII; includes metabolism of halogen-containing compounds.


description: Catalysis of the reaction: UDP-N-acetyl-D-glucosamine = UDP-N-acetyl-D-galactosamine.


corrin metabolic process

description: The chemical reactions and pathways involving corrin, C19H22N4, the fundamental heterocyclic skeleton of the corrinoids. It consists of four reduced pyrrole rings joined into a macrocyclic ring. Corrin is the core of the vitamin B12 molecule.


peptidyl-threonine octanoylation

description: The octanoylation of peptidyl-threonine to form peptidyl-O3-octanoyl-L-threonine, typical of the protein ghrelin.


dCMP deaminase activity

description: Catalysis of the reaction: dCMP + H2O = dUMP + NH3.


Fc-gamma receptor signaling pathway

category: biolink:Pathway biolink:OntologyClass biolink:BiologicalProcess biolink:Occurrent biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: The series of molecular signals initiated by the binding of the Fc portion of immunoglobulin G (IgG) to an Fc-gamma receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. The Fc portion of an immunoglobulin is its C-terminal constant region.


renal capsule specification

description: The regionalization process in which the identity of the renal capsule is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized.


hyponitrite reductase activity

description: Catalysis of the reaction: 2 hydroxylamine + 2 NAD+ = 2 H+ + hyponitrous acid + 2 NADH.


ciliary body morphogenesis

description: The process in which the ciliary body generated and organized. The ciliary body is the circumferential tissue inside the eye composed of the ciliary muscle and ciliary processes.


description: Catalysis of the random hydrolysis of (1->6) linkages in (1->6)-beta-D-glucans.


name: neural crest-derived cardiac glial cell differentiation

description: The process in which a neural crest cell acquires the specialized features of a glial cell of the heart.


name: mitochondrial protein-transporting ATPase activity

description: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O = ADP + phosphate; drives the transport of proteins into the mitochondrion via the mitochondrial inner membrane translocase complex.


name: molybdenum incorporation into metallo-sulfur cluster

description: The incorporation of molybdenum into a metallo-sulfur cluster.


cellular response to glutathione

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glutathione stimulus.


name: formation of peptidyl-cystine persulfide by sulphur transfer from H2S

description: The modification of a peptidyl-cystine residue in a protein by the direct addition of H2S, followed by the removal of 2 protons to form peptidyl-cysteine persulfide.


folate reductase activity

description: Catalysis of the reaction: 7,8-dihydrofolate + NADP+ = folate + NADPH + H+.


glyoxal metabolic process

description: The chemical reactions and pathways involving glyoxal.


name: 1-deoxy-D-xylulose 5-phosphate biosynthetic process

description: The chemical reactions and pathways resulting in the formation of 1-deoxy-D-xylulose 5-phosphate, the 5-phospho derivative of 1-deoxy-D-xylulose. 1-deoxy-D-xylulose 5-phosphate is an intermediate in the non-mevalonate pathway and a common precursor for isoprenoid, thiamin, and pyridoxol biosynthesis.


NAD+ binding

description: Binding to the oxidized form, NAD, of nicotinamide adenine dinucleotide, a coenzyme involved in many redox and biosynthetic reactions.


name: regulation of stomatal complex patterning

description: Any process that modulates the frequency, rate or extent of stomatal complex patterning.


response to mycophenolic acid

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mycophenolic acid stimulus.


name: 3,5-dichloro-THPH methyl transferase activity

description: Catalysis of the reaction: (3,5-dichloro-2,4,6-trihydroxyphenyl)hexan-1-one + S-adenosyl-L-methionine = 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one + H+ + S-adenosyl-L-homocysteine.


name: UDP-glucuronic acid dehydrogenase activity

description: Catalysis of the reaction: UDP-glucuronate + NAD+ = UDP-beta-L-threo-pentapyranos-4-ulose + CO2 + NADH + H+.


description: Catalysis of the reaction: selenocysteine + S-adenosyl-L-methionine = Se-methylselenocysteine + S-adenosyl-homocysteine.


oxalate catabolic process

description: The chemical reactions and pathways resulting in the breakdown of oxalate, the organic acid ethanedioate.


4-hydroxytryptamine kinase activity

description: Catalysis of the reaction: 4-hydroxytryptamine + ATP = 4-hydoxytryptamine 4-phosphate + ADP + H+.


tryptophanyl-tRNA aminoacylation

description: The process of coupling tryptophan to tryptophanyl-tRNA, catalyzed by tryptophanyl-tRNA synthetase. The tryptophanyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2'-OH group of a tryptophan-accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification.


name: mammillotegmental axonal tract development

description: The process in which the mammillotegmental tract progresses over time, from its formation to the mature structure. The mammillotegmental tract is the collection of axons that connects the ventral diencephalon to the tegmentum and pons.


name: very-low-density lipoprotein particle clearance

description: The process in which a very-low-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.


regulation of dopamine secretion

description: Any process that modulates the frequency, rate or extent of the regulated release of dopamine.


name: regulation of the force of skeletal muscle contraction

description: Any process that modulates the frequency, rate or extent of the force of skeletal muscle contraction. The force of skeletal muscle contraction is produced by acto-myosin interaction processes through the formation of cross bridges.


neural plate axis specification

description: The pattern specification process in which the axes of the nervous system are established.


name: NAD-dependent protein de-2-hydroxyisobutyrylase activity

description: Catalysis of the reaction: H2O + N6-(2-hydroxyisobutanoyl)-L-lysyl-[protein] + NAD+ = 2''-O-(2-hydroxyisobutanoyl)-ADP-D-ribose + L-lysyl-[protein] + nicotinamide.


galactoxylomannan biosynthetic process

description: The chemical reactions and pathways resulting in the formation of the exopolysaccharide galactoxylomannan. Galactoxylomannan is produced by a pathogenic fungus and causes paralysis in some animals.


lysosomal membrane organization

description: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lysosomal membrane. A lysosomal membrane is the lipid bilayer surrounding the lysosome and separating its contents from the cell cytoplasm.


7S RNA binding

description: Binding to a 7S RNA, the RNA component of the signal recognition particle (SRP).


name: negative regulation of cellotriose metabolic process

description: Any process that stops, prevents or reduces the frequency, rate or extent of cellotriose metabolic process.


phototropism

description: The movement of an organism, or part of an organism, in response to a light stimulus, usually toward or away from it.


malonyl-CoA biosynthetic process

description: The chemical reactions and pathways resulting in the formation of malonyl-CoA, the S-malonyl derivative of coenzyme A.


name: formation of peptidyl-cystine persulfide by sulphur transfer from free cysteine

description: The modification of a peptidyl-cystine residue in a protein by the transfer of a sulfur atom from a free cysteine (in the process converting the free cysteine to alanine) to the peptidyl-cysteine to form peptidyl-cysteine persulfide.


name: phenol-containing compound metabolic process

description: The chemical reactions and pathways involving a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring.


name: mesonephric nephron tubule morphogenesis

description: The process in which the anatomical structures of a mesonephric nephron tubule are generated and organized. A mesonephric nephron tubule is an epithelial tube that is part of the mesonephric nephron, the functional part of the mesonephros.


premeiotic DNA replication termination

description: Any DNA replication termination involved in meiotic cell cycle DNA replication.


peptidyl-pyrromethane cofactor linkage

description: The covalent binding of a pyrromethane (dipyrrin) cofactor to protein via the sulfur atom of cysteine forming dipyrrolylmethanemethyl-L-cysteine.


description: Catalysis of the reaction: P1-P6-bis(5'-adenosyl) hexaphosphate + H2O = AMP + adenosine 5'-pentaphosphate.


name: negative regulation of vasculature development

description: Any process that stops, prevents or reduces the frequency, rate or extent of vasculature development.


mitochondrial RNA surveillance

description: The set of processes involved in identifying and degrading defective or aberrant RNAs that takes place in the mitochondrion.


name: corticospinal neuron axon guidance through the cerebral peduncle

description: The process in which the migration of an axon growth cone of a pyramidal cell that is part of the corticospinal tract is directed after exiting the internal capsule through the cerebral peduncle in response to a combination of attractive and repulsive cues.


description: The methylation of 5-hydroxy-L-lysine to form peptidyl-N6,N6,N6-trimethyl-5-hydroxy-L-lysine.


name: (R)-4-hydroxyphenyllactate dehydrogenase (NADP+) activity

description: Catalysis of the reaction: NADP+ + (R)-3-(4-hydroxyphenyl)lactate = NADPH + H+ + 3-(4-hydroxyphenyl)pyruvate.


name: regulation of cellodextrin catabolic process

description: Any process that modulates the frequency, rate or extent of cellodextrin catabolic process.


sevenless signaling pathway

description: The series of molecular signals initiated by an extracellular ligand binding to sevenless (sev; a receptor tyrosine kinase) on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.


name: negative regulation of nerve growth factor production

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of production of nerve growth factor (NGF).


eoxin E4 synthase activity

description: Catalysis of the reaction: eoxin D4 + H20 = eoxin E4 + glycine.


name: medulla reticulospinal tract morphogenesis

description: Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the medulla towards target cells in the spinal cord.


name: cellular response to lipoprotein particle stimulus

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipoprotein particle stimulus.


FAT10 conjugating enzyme activity

description: Isoenergetic transfer of FAT10 from one protein to another via the reaction X-FAT10 + Y = Y-FAT10 + X, where both the X-FAT10 and Y-FAT10 linkages are thioester bonds between the C-terminal amino acid of FAT10 and a sulfhydryl side group of a cysteine residue.


name: regulation of cell differentiation involved in embryonic placenta development

description: Any process that modulates the rate, frequency or extent of cell differentiation that contributes to the progression of the placenta over time, from its initial condition to its mature state.


name: activation-induced cell death of T cells

description: A T cell apoptotic process that occurs towards the end of the expansion phase following the initial activation of mature T cells by antigen and is triggered by T cell receptor stimulation and signals transmitted via various surface-expressed members of the TNF receptor family such as Fas ligand, Fas, and TNF and the p55 and p75 TNF receptors.


description: Catalysis of the reaction: nucleoside triphosphate + aminoglycoside = diphosphate + nucleotidylaminoglycoside.


name: positive regulation of CD8-positive, alpha-beta T cell proliferation

description: Any process that activates or increases the frequency, rate or extent of CD8-positive, alpha-beta T cell proliferation.


homocysteine metabolic process

description: The chemical reactions and pathways involving homocysteine, the amino acid alpha-amino-gamma-mercaptobutanoic acid. Homocysteine is an important intermediate in the metabolic reactions of its S-methyl derivative, methionine.


snRNA methylation

description: The posttranscriptional addition of methyl groups to specific residues in an snRNA molecule.


embryonic hindlimb morphogenesis

description: The process, occurring in the embryo, by which the anatomical structures of the hindlimbs are generated and organized. The hindlimbs are the posterior limbs of an animal.


regulation of vesicle docking

description: Any process that modulates the frequency, rate or extent of vesicle docking.


antennal development

description: The process whose specific outcome is the progression of the antenna over time, from its formation to the mature structure. The antenna are the sensory structures on the head that are capable of detecting various environmental stimuli.


angioblast cell differentiation

description: The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of an angioblast cell. Angioblasts are one of the two products formed from hemangioblast cells (the other being pluripotent hemopoietic stem cells).


peptidyl-lysine malonylation

description: The addition of a malonyl group (CO-CH2-CO) to peptidyl-lysine to form N6-malonyl-L-lysine.


regulation of B cell activation

description: Any process that modulates the frequency, rate or extent of B cell activation.


name: adult salivary gland boundary specification

description: Determination in an adult organism of where the salivary gland forms, the total number of salivary gland cells and how many cells are allocated to each of the specialised cell types within the salivary gland.


name: propionate transmembrane transporter activity

description: Enables the transfer of propionate from one side of a membrane to the other. Propionate (or propanoate) is the organic acid CH3-CH2-COOH.


description: The dehydration of peptidyl-S-carbamoyl-L-cysteine to form peptidyl-S-cyano-L-cysteine.


description: Catalysis of the reaction: a branched-chain amino acid + 2-oxoglutarate = L-glutamate + a 2-oxocarboxylate derived from the branched-chain amino acid.


negative regulation of ovulation

description: Any process that stops, prevents, or reduces the frequency, rate or extent of ovulation, the release of a mature ovum/oocyte from an ovary.


name: symbiont-mediated perturbation of host actin cytoskeleton via actin filament reorganization

description: The process in which an organism effects a change that impairs the structure or function of the host actin cytoskeleton by reorganizing the actin filaments, in a way that keeps the total filementous actin remains approximately constant. The host is defined as the larger of the organisms involved in a symbiotic interaction.


cell-matrix recognition

description: Cell recognition that involves the interaction of the cell with the extracellular matrix.


mammary gland duct regression in males

description: The process in which the epithelium of the mammary duct is destroyed in males.


N-methyl nucleosidase activity

description: Catalysis of the reaction: 7-methylxanthosine + H2O = 7-methylxanthine + H+ + ribofuranose.


name: cardiac epithelial to mesenchymal transition

description: A transition where a cardiac epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.


phosphoserine-tRNA(Cys) ligase activity

description: Catalysis of the reaction: tRNA(Cys) + O-phospho-L-serine + ATP = AMP + diphosphate + phosphoseryl-tRNA(Cys).


name: protein localization to cytosolic proteasome complex

description: A process in which a protein is transported to, or maintained in, a location within a cytosolic proteasome complex.


nucleobase binding

description: Binding to a nucleobase, any of a class of pyrmidines or purines, organic nitrogenous bases.


name: protein localization to actin cortical patch

description: A process in which a protein is transported to, or maintained in, an actin cortical patch.


phlobaphene metabolic process

description: The chemical reactions and pathways involving phlobaphenes, red pigments with oligomeric or polymeric structure derived from the flavonoid intermediate flavan-4-ols.


name: positive regulation of heart rate by norepinephrine

description: The process in which the secretion of norepinephrine into the bloodstream or released from nerve endings increases the rate of heart muscle contraction.


basket cell precursor proliferation

description: The multiplication or reproduction of neuroblasts that will give rise to basket cells. A cerebellar basket cell is an inhibitory GABAergic interneuron found in the cerebellar cortex.


regulation of G0 to G1 transition

description: A cell cycle process that modulates the rate or extent of the transition from the G0 quiescent state to the G1 phase.


gluconate dehydratase activity

description: Catalysis of the reaction: D-gluconate = 2-dehydro-3-deoxy-D-gluconate + H2O.


name: positive regulation of mast cell proliferation

description: Any process that activates or increases the rate or extent of mast cell proliferation.


7SK snRNA binding

description: Binding to a 7SK small nuclear RNA (7SK snRNA).


bisdemethoxycurcumin synthase activity

description: Catalysis of the reaction: 2 4-coumaryl-CoA + malonyl-CoA + H2O + H+ = 3 coenzyme A + bisdemethoxycurcumin + 2 carbon dioxide.


description: Catalysis of the reaction: S-adenosyl-L-methionine + myricetin = S-adenosyl-L-homocysteine + laricitrin.


ectopic germ cell programmed cell death

description: Programmed cell death of an errant germ line cell that is outside the normal migratory path or ectopic to the gonad. This is an important mechanism of regulating germ cell survival within the embryo.


description: Catalysis of the reaction: L-glutamate + ATP + NADPH = ADP + L-glutamate gamma-semialdehyde + NADP+ + phosphate.


response to blue light

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a blue light stimulus. Blue light is electromagnetic radiation with a wavelength of between 440 and 500nm.


name: glial cell migration in anterior lateral line nerve

description: The movement of a glial cell along the axons in the anterior lateral line nerve.


name: regulation of proline import across plasma membrane

description: Any process that modulates the frequency, rate or extent of proline import into cell.


bromide peroxidase activity

description: Catalysis of the reaction: 2 R-H + 2 bromide + H2O2 = 2 R-Br + 2 H2O. Enzymes with this activity often accept other halide ions as substrates, including chloride and iodide.


name: regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning

description: Any process that modulates the frequency, rate or extent of smoothened signaling pathway involved in dorsal/ventral neural tube patterning.


description: Catalysis of the reaction: CTP + choline phosphate = diphosphate + CDP-choline.


schizogony

description: Cell division by multiple fission in which nuclei and other organelles in the parent cell divide repeatedly and move to the cell periphery before internal membranes develop around them, producing a large number of daughter cells simultaneously.


name: inhibitory C-type lectin receptor signaling pathway

description: The series of molecular signals initiated by an extracellular ligand binding to an inhibitory C-type lectin receptor capable of inhibiting an immune effector process contributing to an immune response.


vacuole-mitochondria membrane tethering

description: The attachment of a mitochondrial membrane to a vacuolar membrane via molecular tethers that physically bridge their respective membranes and attach them to each other. The tethering may facilitate exchange of metabolites between the organelles.


description: Catalysis of the reaction: coniferyl aldehyde + H2O + NAD(P)+ = ferulate + NAD(P)H + H+.


heme oxidation

description: The chemical reactions and pathways resulting in the loss of electrons from one or more atoms in heme.


name: negative regulation of muscle cell apoptotic process

description: Any process that decreases the rate or frequency of muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a muscle cell and result in its death.


description: Catalysis of the reaction: 1,2-dihydroxyphenanthrene + UDP-glucose = 2-hydroxy-1-phenanthryl-beta-D-glucopyranoside + UDP.


name: symbiont entry into host cell via disruption of host cell envelope

description: The disruption by a symbiont of host cell envelope components to allow entry into the host cell.


plasmid maintenance

description: The maintenance of the integrity of extrachromosomal plasmid DNA; includes processes that ensure plasmids are retained in the daughter cells after cell division.


R-loop processing

description: A DNA metabolic process that results in the disassembly of R-loops. R-loops are three-stranded nucleic acid structures consisitng of an RNA:DNA heteroduplex and a looped-out non-template strand. Aberrant formation and persistence of R-loops block transcription elongation and cause DNA damage. Mechanisms that resolve R-loops are essential for genome stability.


name: deoxynucleotide transmembrane transporter activity

description: Catalyzes transport of all four deoxy (d) NDPs, and, less efficiently, the corresponding dNTPs, in exchange for dNDPs, ADP, or ATP.


name: cell growth mode switching, filamentous to budding

description: The process in which a cell switches from growing as a filament (elongated cells attached end-to-end) to growing as a round budding cell. An example of this is observed in Candida albicans.


name: negative regulation of glomerular mesangial cell proliferation

description: Any process that decreases the frequency, rate or extent of glomerular mesangial cell proliferation.


cerebellum vasculature morphogenesis

description: The process in which the vasculature of the cerebellum is generated and organized.


name: regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway

description: Any process that modulates the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing 2 (NOD2) pathway.


cellular response to diosgenin

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diosgenin stimulus.


dihydroorotase activity

description: Catalysis of the reaction: (S)-dihydroorotate + H2O = N-carbamoyl-L-aspartate + H+.


renal sodium excretion

description: The elimination of sodium ions from peritubular capillaries (or surrounding hemolymph in invertebrates) into the renal tubules to be incorporated subsequently into the urine.


description: Catalysis of the reaction: 1,2,3-tri-(9Z,12Z)-octadecadienoylglycerol + N-(30-hydroxytriacontanoyl)-sphing-4-enine = di-(9Z,12Z)-octadecadienoylglycerol + N-[30-(9Z,12Z-octadecadienoyloxy)-triacontanoyl]-sphing-4-enine.


propan-2-ol metabolic process

description: The chemical reactions and pathways involving propan-2-ol.


dehiscence

description: The opening of an anther, fruit or other structure, which permits the escape of reproductive bodies contained within it.


isoflavonoid metabolic process

description: The chemical reactions and pathways involving isoflavonoids, a group of water-soluble phenolic derivatives, isomeric with flavonoids, containing a flavan skeleton. They are differentiated from flavonoids by the point of attachment of the aromatic ring group.


CCL19-activated CCR7 signaling pathway

description: The series of molecular signals initiated by the binding of the C-C chemokine CCL19 to a C-C chemokine type 7 receptor (CCR7) on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.


name: cell motility involved in cerebral cortex radial glia guided migration

description: The movement of a cell along the process of a radial glial cell involved in cerebral cortex glial-mediated radial migration.


name: negative regulation of catecholamine metabolic process

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving catecholamine.


anhydrosialidase activity

description: Catalysis of the reaction: an N-acetylneuraminate glycoside = 2,7-anhydro-alpha-N-acetylneuraminate + an alpha-sialyl group. This reaction is the elimination of alpha-sialyl groups in N-acetylneuraminic acid glycosides, releasing 2,7-anhydro-alpha-N-acetylneuraminate.


nucleic acid biosynthetic process

description: The biosynthetic process resulting in the formation of a nucleic acid.


CD27 signaling pathway

description: The series of molecular signals initiated by the binding of the cell surface receptor CD27 to its physiological ligand CD70, and ending with the regulation of a downstream cellular process, e.g. transcription.


glucocorticoid metabolic process

description: The chemical reactions and pathways involving glucocorticoids, hormonal C21 corticosteroids synthesized from cholesterol. Glucocorticoids act primarily on carbohydrate and protein metabolism, and have anti-inflammatory effects.


name: Mo-molybdopterin cofactor catabolic process

description: The chemical reactions and pathways resulting in the breakdown of the Mo-molybdopterin cofactor, essential for the catalytic activity of some enzymes. The cofactor consists of a mononuclear molybdenum (Mo) ion coordinated by one or two molybdopterin ligands.


phosphogluconate dehydratase activity

description: Catalysis of the reaction: 6-phospho-D-gluconate = 2-dehydro-3-deoxy-6-phospho-D-gluconate + H2O.


description: Catalysis of the reaction: UDP-alpha-D-glucose(2-) + medicagenate = UDP(3-) + a medicagenate monoglucoside.


quinoline 2-oxidoreductase activity

description: Catalysis of the reaction: quinoline + acceptor + H2O = isoquinolin-1(2H)-one + reduced acceptor.


name: negative regulation of lamellocyte differentiation

description: Any process that stops, prevents, or reduces the frequency, rate or extent of lamellocyte differentiation. Lamellocytes differentiate massively in the lymph glands after parasitization and are large flat cells devoted to encapsulation of invaders too large to be phagocytosed by plasmatocytes.


name: negative regulation of fibroblast apoptotic process

description: Any process that stops, prevents or reduces the frequency, rate or extent of fibroblast apoptotic process.


name: hypoxia-inducible factor-proline dioxygenase activity

description: Catalysis of the reaction: 2-oxoglutarate + L-prolyl-[hypoxia-inducible factor alpha subunit] + O2 = CO2 + succinate + trans-4-hydroxy-L-prolyl-[hypoxia-inducible factor alpha subunit].


name: saccharopine dehydrogenase (NAD+, L-lysine-forming) activity

description: Catalysis of the reaction: L-saccharopine + H2O + NAD+ = 2-oxoglutarate + L-lysine + H+ + NADH.


description: Catalysis of the reaction: UDP-N-acetyl-alpha-D-quinovosamine + NAD(P) = UDP-2-acetamido-4-dehydro-2,6-dideoxy-beta-D-glucose + H+ + NAD(P)H.


specification of axis polarity

description: The pattern specification process in which the polarity of a body or organ axis is established and maintained.


name: positive regulation of T cell extravasation

description: Any process that activates or increases the frequency, rate or extent of T cell extravasation.


name: negative regulation of cell differentiation involved in stem cell population maintenance

description: Any negative regulation of cell differentiation that is involved in stem cell population maintenance.


heterotrimeric G-protein binding

description: Binding to a heterotrimeric G-protein.


description: Catalysis of the reaction: phenylacetyl-CoA + L-glutamine = CoA + alpha-N-phenylacetyl-L-glutamine.


slime layer organization

description: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a slime layer. A slime layer is an easily removed, diffuse, unorganized layer of extracellular material that surrounds a cell.


protein-heme P460 linkage

description: The linkage of protein to heme P460.


background adaptation

description: Any process in which an organism changes its pigmentation (lightening in response to a brighter environment or darkening in response to a dimmer environment) in response to a change in light intensity.


name: regulation of neurotransmitter loading into synaptic vesicle

description: Any process that modulates the frequency, rate or extent of neurotransmitter loading into synaptic vesicles.


name: D-arabitol catabolic process to xylulose 5-phosphate

description: The chemical reactions and pathways resulting in the breakdown of D-arabitol to form xylulose 5-phosphate. D-arabitol is converted into D-xylulose, which is then phosphorylated to form D-xylulose-5-phosphate.


preribosome binding

description: Binding to a preribosome.


RNA polymerase IV activity

description: Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template that contains an RNA polymerase IV specific promoter to direct initiation and catalyses DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.


verruculogen biosynthetic process

description: The chemical reactions and pathways resulting in the formation of verruculogen.


anaerobic fructose catabolic process

description: The chemical reactions and pathways resulting in the breakdown of fructose that occurs in the absence of oxygen.


name: molybdenum cofactor cytidylyltransferase activity

description: Catalysis of the reaction CTP + molybdenum cofactor = diphosphate + cytidylyl molybdenum cofactor.


histidine N-acetyltransferase activity

description: Catalysis of the reaction: L-histidine + acetyl-CoA = N(alpha)-acetyl-L-histidine + CoA + H+.


retinal blood vessel morphogenesis

description: The process whose specific outcome is the progression of a blood vessel of the retina over time, from its formation to the mature structure.


name: positive regulation of nematode larval development

description: Any process that increases the rate, frequency, or extent of nematode larval development, the process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew.


eye-antennal disc morphogenesis

description: The process in which the anatomical structures derived from the eye-antennal disc are generated and organized. This includes the transformation of an eye-antennal imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into recognizable adult structures including the eye, antenna, head capsule and maxillary palps.


name: right ventricular compact myocardium morphogenesis

description: The process in which the anatomical structures of the right ventricular compact myocardium are generated and organized.


name: positive regulation of dopaminergic neuron differentiation

description: Any process that activates or increases the frequency, rate or extent of dopaminergic neuron differentiation.


name: negative regulation of L-dopa decarboxylase activity

description: Any process that stops, prevents or reduces the frequency, rate or extent of L-dopa decarboxylase activity.


engulfment of apoptotic cell

description: The removal of the apoptotic cell by phagocytosis, by a neighboring cell or by a phagocyte.


regulation of foraging behavior

description: Any process that modulates the frequency, rate or extent of foraging behavior.


name: hormonal regulation of the force of heart contraction

description: The process in which the hormones modulates the force of heart muscle contraction. A hormone is one of a group of substances formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells, in the same organism, upon which they have a specific regulatory action.


gentisate decarboxylase activity

description: Catalysis of the reaction: 2,5-dihydroxybenzoate + H+ = CO2 + hydroquinone.


response to interleukin-6

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-6 stimulus.


protein-hormone receptor activity

description: Combining with a protein hormone to initiate a change in cell activity.


box H/ACA sno(s)RNA 3'-end processing

description: Any process involved in forming the mature 3' end of a box H/ACA RNA molecule.


peptide cross-linking via L-cystine

description: The oxidation of two peptidyl-cysteine residues to form a peptidyl-L-cystine (dicysteine) in which segments of peptide chain are linked by a disulfide bond; the cross-link may be between different or the same peptide chain.


regulation of nitrogen utilization

description: Any process that modulates the frequency, rate or extent of nitrogen utilization.


myoblast differentiation

description: The process in which a relatively unspecialized cell acquires specialized features of a myoblast. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into striated muscle fibers.


name: positive regulation of systemic acquired resistance

description: Any process that activates or increases the frequency, rate or extent of systemic acquired resistance.


name: myeloid dendritic cell antigen processing and presentation

description: The process in which a myeloid dendritic cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex.


gibberellin biosynthetic process

description: The chemical reactions and pathways resulting in the formation of gibberellin. Gibberellins are a class of highly modified terpenes that function as plant growth regulators.


description: The series of molecular signals initiated by interleukin-5 binding to its receptor on the surface of a cell, and ending with the regulation of a downstream cellular process, e.g. transcription.


name: phytochrome chromophore biosynthetic process

description: The chemical reactions and pathways resulting in the formation of the phytochrome chromophore. The phytochrome chromophore is a linear tetrapyrrolic prosthetic group covalently attached to the large soluble protein phytochrome. Light absorption by the phytochrome chromophore triggers photoconversion between two spectrally distinct forms of the photoreceptor: Pr, the red light absorbing form, and Pfr, the far red light absorbing form.


myrtenol dehydrogenase activity

description: Catalysis of the reaction: myrtenol + O2 + 2 H+ + 2 e- = 2 H2O + myrtenal.


mRNA 3'-UTR AU-rich region binding

description: Binding to a region containing frequent adenine and uridine bases within the 3' untranslated region of a mRNA molecule or in pre-mRNA intron. The ARE-binding element consensus is UUAUUUAUU. ARE-binding proteins control the stability and/or translation of mRNAs.


name: development of primary male sexual characteristics

description: The process whose specific outcome is the progression of the primary male sexual characteristics over time, from their formation to the mature structures. The primary male sexual characteristics are the testes, and they develop in response to sex hormone secretion.


regulation of mitotic cytokinesis

description: Any process that modulates the frequency, rate or extent of mitotic cytokinesis.


name: establishment of plant organ orientation

description: The process that determines the orientation of a plant organ or tissue with reference to an axis.


cardiac neuron fate commitment

description: The process in which the developmental fate of a cell becomes restricted such that it will develop into a neuron of the heart.


response to desipramine

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a desipramine stimulus.


pro-B cell differentiation

description: The process in which a precursor cell type acquires the specialized features of a pro-B cell. Pro-B cells are the earliest stage of the B cell lineage and undergo heavy chain D and J gene rearrangements, although they are not fully committed.


mannan biosynthetic process

description: The chemical reactions and pathways resulting in the formation of mannan, the main hemicellulose of soft (coniferous) wood, made up of D-mannose, D-glucose and D-galactose.


name: fatty acid beta-oxidation, unsaturated, even number

description: A fatty acid beta-oxidation pathway by which fatty acids having cis-double bonds on even-numbered carbons are degraded. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and ends when only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively).


name: cellular response to catecholamine stimulus

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a catecholamine stimulus. A catecholamine is any of a group of biogenic amines that includes 4-(2-aminoethyl)pyrocatechol [4-(2-aminoethyl)benzene-1,2-diol] and derivatives formed by substitution.


name: eukaryotic translation initiation factor 4F complex assembly

description: The aggregation, arrangement and bonding together of a set of components to form the eukaryotic translation initiation factor 4F complex.


tRNA N-acetyltransferase activity

description: Catalysis of the reaction: a cytidine in tRNA + acetyl-CoA + ATP + H2O = ADP + an N4-acetylcytidine in tRNA + CoA + H+ + phosphate.


terpenoid catabolic process

description: The chemical reactions and pathways resulting in the breakdown of terpenoids, any member of a class of compounds characterized by an isoprenoid chemical structure.


name: positive regulation of oogonium development

description: Any process that activates, maintains or increases the frequency, rate or extent of oogonium development, a process that leads to the formation of a female gametangium of oomycetes, containing one or more gametes.


alcohol O-hexanoyltransferase activity

description: Catalysis of the reaction: hexanoyl-CoA + an alcohol = CoA + a hexyl ester.


name: cis-zeatin UDP glycosyltransferase activity

description: Catalysis of the reaction: UDP-alpha-D-glucose + cis-zeatin = H+ + 9-(alpha-D-glucosyl)-cis-zeatin + UDP.


regulation of platelet aggregation

description: Any process that modulates the rate, frequency or extent of platelet aggregation. Platelet aggregation is the adhesion of one platelet to one or more other platelets via adhesion molecules.


inosine kinase activity

description: Catalysis of the reaction: ATP + inosine = ADP + IMP.


description: The chemical reactions and pathways resulting in the breakdown of (+)-epi-alpha-bisabolol.


name: negative regulation of metabolic activity involved in hibernation

description: The slowing of metabolic processes to very low levels in order to conserve energy as a part of hibernation.


name: cellular biogenic amine catabolic process

description: The chemical reactions and pathways occurring at the level of individual cells resulting in the breakdown of biogenic amines, any of a group of naturally occurring, biologically active amines, such as norepinephrine, histamine, and serotonin, many of which act as neurotransmitters.


cAMP-dependent protein kinase activity

description: cAMP-dependent catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein.


name: histone H3K36 trimethyltransferase activity

description: Catalysis of the reaction: L-lysyl36-[histone H3] + 3 S-adenosyl-L-methionine = 3 H+ + N6,N6,N6-trimethyl-L-lysyl36-[histone H3] + 3 S-adenosyl-L-homocysteine. This reaction is the successive addition of three methyl groups to the lysine residue at position 36 of histone H3, producing histone H3K36me3.


name: semaphorin-plexin signaling pathway involved in neuron projection guidance

description: Any semaphorin-plexin signaling pathway that is involved in neuron projection guidance.


description: Catalysis of the reaction: 7,8-dihydro-7,8-dihydroxykynurenate + NAD+ = 7,8-dihydroxykynurenate + H+ + NADH.


name: zeaxanthin bis(beta-D-glucoside) metabolic process

description: The chemical reactions and pathways involving zeaxanthin bis(beta-D-glucoside).


description: Catalysis of the reaction: UDP-alpha-D-glucose + gypsogenin = gypsogenin-28-beta-D-glucoside + UDP.


(+)-delta-cadinene synthase activity

description: Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = diphosphate + (+)-delta-cadinene.


name: regulation of anterograde synaptic vesicle transport

description: Any process that modulates the frequency, rate or extent of anterograde synaptic vesicle transport.


protein C-linked glycosylation

description: A protein glycosylation process in which a carbohydrate or carbohydrate derivative unit is added to a protein via a C atom.


hermaphrodite somatic sex determination

description: The determination of sex and sexual phenotypes in a hermaphroditic organism's soma. An example of this is found in Caenorhabditis elegans.


name: positive regulation of DNA damage response, signal transduction by p53 class mediator

description: Any process that activates, maintains or increases the rate of the cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage.


lymph circulation

description: The flow of lymph through the body of an animal.


name: inorganic diphosphate transmembrane transporter activity

description: Enables the transfer of inorganic diphosphate across a membrane.


name: glutamate:sodium symporter activity

description: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glutamate(out) + Na+(out) = glutamate(in) + Na+(in).


ornithine N-benzoyltransferase activity

description: Catalysis of the reaction: L-ornithine + 2 benzoyl-CoA = N(2),N(5)-dibenzoyl-L-ornithine + 2 CoA + 2 H+.


description: The acetylation of the N-terminal methionine of proteins to form the derivative N-acetyl-L-methionine.


name: mannose to fructose-6-phosphate catabolic process

description: The chemical reactions and pathways in which mannose, the aldohexose manno-hexose, is converted to fructose-6-phosphate.


coenzyme A metabolic process

description: The chemical reactions and pathways involving coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester.


5'-3' DNA/RNA helicase activity

description: Unwinding of a DNA/RNA duplex in the 5' to 3' direction, driven by ATP hydrolysis.


SCF complex assembly

description: The aggregation, arrangement and bonding together of a set of components to form the SKP1-Cullin/Cdc53-F-box protein ubiquitin ligase (SCF) complex.


name: positive regulation of acetylcholine metabolic process

description: Any process that increases the rate, frequency or extent of the chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues.


regulation of xylan catabolic process

description: Any process that modulates the frequency, rate or extent of xylan catabolic process.


noradrenergic neuron fate commitment

description: The process in which the developmental fate of a cell becomes restricted such that it will develop into a noradrenergic neuron.


name: positive regulation of erythrocyte differentiation

description: Any process that activates or increases the frequency, rate or extent of erythrocyte differentiation.


mesonephric distal tubule morphogenesis

description: The process in which the anatomical structures of a mesonephric distal tubule are generated and organized. The mesonephric distal tubule is a mesonephric nephron tubule that begins at the macula densa and extends to the mesonephric connecting tubule.


manganese ion homeostasis

description: Any process involved in the maintenance of an internal steady state of manganese ions within an organism or cell.


name: vascular associated smooth muscle cell migration

description: The orderly movement of a vascular associated smooth muscle cell from one site to another.


morphine 6-dehydrogenase activity

description: Catalysis of the reaction: morphine + NAD(P)+ = morphinone + NAD(P)H + H+.


name: iron-sulfur-molybdenum cofactor metabolic process

description: The chemical reactions and pathways involving iron-sulfur-molybdenum cofactor.


name: positive regulation of triglyceride transport

description: Any process that activates or increases the frequency, rate or extent of triglyceride transport.


cellular response to cesium ion

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cesium stimulus.


bromoxynil nitrilase activity

description: Catalysis of the reaction: 3,5-dibromo-4-hydroxybenzonitrile + 2 H2O = 3,5-dibromo-4-hydroxybenzoate + NH4. Involved in the bacterial degradation of the herbicide bromoxynil.


undecan-2-one biosynthetic process

description: The chemical reactions and pathways resulting in the formation of undecan-2-one.


dCTP deaminase activity

description: Catalysis of the reaction: dCTP + H2O = dUTP + NH3.


name: inositol hexakisphosphate 3-kinase activity

description: Catalysis of the reaction: ATP + 1D-myo-inositol hexakisphosphate = ADP + 3-diphospho-1D-myo-inositol (1,2,4,5,6)pentakisphosphate.


UDP-D-xylose metabolic process

description: The chemical reactions and pathways involving UDP-D-xylose, uridinediphosphoxylose, a substance composed of xylose in glycosidic linkage with uridine diphosphate.


name: adenylate cyclase-activating G protein-coupled bile acid receptor signaling pathway

description: An adenylate cyclase-activating G protein-coupled receptor signaling pathway initiated by a ligand binding to a bile acid receptor on the surface of the target cell, and ending with the regulation of a downstream cellular process.


protein localization to nucleoplasm

description: A process in which a protein is transported to, or maintained in, a location within the nucleoplasm.


cell differentiation in hindbrain

description: The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mature cells of the hindbrain. Differentiation includes the processes involved in commitment of a cell to a specific fate.


stilbene catabolic process

description: The chemical reactions and pathways resulting in the breakdown of stilbenes, a class of polyketide compounds formed from cinnamic acid and three molecules of malonyl CoA.


thiocyanate metabolic process

description: The chemical reactions and pathways involving thiocyanate, the anion of thiocyanic acid, a toxic cyanide derivative commonly formed as a by-product in the production of gas for fuel, coke, and substances for chemical industries.


peptidyl-lysine methylation

description: The methylation of peptidyl-lysine to form either the mono-, di- or trimethylated derivative.


name: positive regulation of acute inflammatory response to non-antigenic stimulus

description: Any process that activates or increases the frequency, rate, or extent of an acute inflammatory response to a non-antigenic stimulus.


name: regulation of carbohydrate catabolic process

description: Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of carbohydrates.


name: negative regulation of response to wounding

description: Any process that stops, prevents or reduces the frequency, rate or extent of response to wounding.


description: The carbamylation of the N-terminal alanine of proteins to form the derivative N-carbamoyl-L-alanine.


description: The chemical reactions and pathways resulting in the formation of naphtho-gamma-pyrone.


7-methylguanosine cap hypermethylation

description: Hypermethylation of the 7-(mono)methylguanosine (m(7)G) cap structure at the 2' position of the guanosine residue to convert a mono-methylated cap to a 2,2,7-trimethylguanosine cap structure. This type of cap modification occurs on small nuclear RNAs (snRNAs) and small nucleolar RNAs (snoRNAs) and is dependent on prior guanine-N7 methylation.


UMP/dUMP kinase activity

description: Catalysis of the reaction: ATP + (d)UMP = ADP + (d)UDP.


name: negative regulation of pulmonary blood vessel remodeling

description: Any process that stops, prevents or reduces the frequency, rate or extent of pulmonary blood vessel remodeling.


name: negative regulation of glucose transmembrane transport

description: Any process that decreases the frequency, rate or extent of glucose transport across a membrane. Glucose transport is the directed movement of the hexose monosaccharide glucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


name: Notch signaling pathway involved in camera-type eye photoreceptor fate commitment

description: The series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell that contributes to the commitment of a precursor cell to a eye photoreceptor fate.


response to type I interferon

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a type I interferon stimulus. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.


name: regulation of CD4-positive, alpha-beta T cell activation

description: Any process that modulates the frequency, rate or extent of CD4-positive, alpha-beta T cell activation.


name: ABC-type oligogalacturonide transporter activity

description: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + oligogalacturonide(out) = ADP + phosphate + oligogalacturonide(in).


regulation of viral transcription

description: Any process that modulates the frequency, rate or extent of the transcription of the viral genome.


name: negative regulation of microglial cell mediated cytotoxicity

description: Any process that stops, prevents or reduces the frequency, rate or extent of microglial cell mediated cytotoxicity.


name: regulation of vascular endothelial growth factor receptor signaling pathway

description: Any process that modulates the frequency, rate or extent of vascular endothelial growth factor receptor signaling pathway activity.


description: Catalysis of the reaction: [(1->4)-alpha-D-galacturonide](n) + H2O = [(1->4)-alpha-D-galacturonide](n-1) + D-galacturonate.


name: negative regulation by host of viral genome replication

description: A process in which a host organism stops, prevents or reduces the frequency, rate or extent of viral genome replication.


name: negative regulation of small intestine smooth muscle contraction

description: Any process that stops, prevents or reduces the frequency, rate or extent of small intestine smooth muscle contraction.


name: positive regulation of adipose tissue development

description: Any process that activates or increases the frequency, rate or extent of adipose tissue development.


specification of ovule identity

description: The regionalization process in which the identity of an ovule is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized.


prevention of polyspermy

description: The negative regulation of fertilization process that takes place as part of egg activation, ensuring that only a single sperm fertilizes the egg.


4-phenanthrol sulfotransferase activity

description: Catalysis of the reaction: 4-phenanthrol + X-SO3(-) = HX + 4-phenanthrylsulfate.


response to yeast

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a yeast species.


high-affinity IgA receptor activity

description: Combining with high affinity with an immunoglobulin of an IgA isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


description: Catalysis of the reaction: coproporphyrinogen III + 2 S-adenosyl-L-methionine = protoporphyrinogen IX + 2 CO2 + 2 L-methionine + 2 5'-deoxyadenosine.


name: anterograde trans-synaptic signaling by trans-synaptic protein complex

description: Cell-cell signaling from presynapse to postynapse, across the synaptic cleft, mediated by a trans-synaptic protein complex.


neuroblast fate commitment

description: The process in which the developmental fate of a cell becomes restricted such that it will differentiate into a neuroblast.


name: RNA-binding transcription regulator activity

description: A transcription regulator activity that modulates the transcription of specific gene sets via selective and non-covalent binding to a specific RNA sequence. This function is known to occur in phages and viruses, for example the lambda N and the HIV tat proteins are necessary to allow RNA polymerase to read through terminator sequences.


name: specification of metanephric distal tubule identity

description: The process in which the distal tubule of the metanephric nephron acquires its identity.


description: Catalysis of the reaction: purine nucleoside + phosphate = purine + alpha-D-ribose 1-phosphate.


selenomethionine gamma-lyase activity

description: Catalysis of the reaction: L-Selenomethionine + H2O => Methaneselenol + Ammonia + 2-oxobutanoic acid.


description: Catalysis of the reaction: poly(ribitol phosphate) + UDP-D-glucose = beta-D-glucosylpoly(ribitol phosphate) + UDP.


description: The series of molecular signals initiated by interleukin-1 binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.


taxoid 7beta-hydroxylase activity

description: Catalysis of the reaction: taxusin + [reduced NADPH-hemoprotein reductase] + O2 = 7beta-hydroxytaxusin + [oxidized NADPH-hemoprotein reductase] + H2O and 2alpha-hydroxytaxusin + [reduced NADPH-hemoprotein reductase] + O2 = 2alpha,7beta-dihydroxytaxusin + [oxidized NADPH-hemoprotein reductase] + H2O.


name: carbohydrate-importing ABC transporter activity

description: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + carbohydrate(out) -> ADP + phosphate + carbohydrate(in).


R1/R6 development

description: The process whose specific outcome is the progression of the R1 and R6 pair of photoreceptors in the eye over time, from their formation to the mature structures. R1 and R6 are paired photoreceptors that contribute to the outer rhabdomeres. An example of this process is found in Drosophila melanogaster.


hexose oxidase activity

description: Catalysis of the reaction: hexose + O2 = aldono-1,5-lactone + H202.


name: negative regulation of MyD88-dependent toll-like receptor signaling pathway

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of MyD88-dependent toll-like receptor signaling pathway.


name: dihydropyrimidine dehydrogenase (NAD+) activity

description: Catalysis of the reaction: a 5,6-dihydropyrimidine (5,6-dihydrouracil or 5,6-dihydrothymine) + NAD+ = a pyrimidine (uracil or thymine) + NADH + H+.


name: negative regulation of cerebellar neuron development

description: Any process that stops, prevents or reduces the frequency, rate or extent of cerebellar neuron development.


regulation of mRNA export from nucleus

description: Any process that modulates the frequency, rate or extent of the directed movement of mRNA from the nucleus to the cytoplasm.


name: glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity

description: Catalysis of the reaction: D-glyceraldehyde 3-phosphate + NAD+ + H2O = 3-phospho-D-glycerate + NADH + H+.


imaginal disc development

description: The process whose specific outcome is the progression of the imaginal disc over time, from its formation to the metamorphosis to form adult structures. Imaginal discs are epithelial infoldings in the larvae of holometabolous insects that develop into adult structures (legs, antennae, wings, etc.).


name: determination of lung left/right asymmetry

description: Determination of the asymmetric location of the lungs with respect to the left and right halves of the organism.


carbonyl reductase (NADPH) activity

description: Catalysis of the reaction: R-CHOH-R' + NADP+ = R-CO-R' + NADPH + H+.


ascending aorta morphogenesis

description: The process in which the anatomical structures of the ascending aorta are generated and organized. The ascending aorta is the portion of the aorta in a two-pass circulatory system that lies between the heart and the arch of aorta. In a two-pass circulatory system blood passes twice through the heart to supply the body once.


name: oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor

description: Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces oxygen.


name: CD8-positive, alpha-beta T cell differentiation involved in immune response

description: The process in which an antigenically naive CD8-positive, alpha-beta T cell acquires the specialized features of an effector, regulatory, or memory T cell as part of an immune response. Effector T cells include cells which provide T cell help or exhibit cytotoxicity towards other cells.


name: delphinidin 3-O-glucoside 7-O-glucosyltransferase (feruloyl-glucose dependent) activity

description: Catalysis of the reaction: delphinidin 3-O-beta-D-glucoside + 1-O-feruloyl-beta-D-glucose = delphinidin 3,7-di O-beta-D-glucoside + ferulate + H+.


response to bisphenol A

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bisphenol A stimulus.


name: regulation of mesenchymal to epithelial transition involved in mesonephros morphogenesis

description: Any process that modulates the frequency, rate or extent of mesenchymal to epithelial transition involved in mesonephros morphogenesis.


name: positive regulation of mammary placode formation by mesenchymal-epithelial signaling

description: Any process that initiates the formation of a mammary placode through a mechanism that mediates the transfer of information from a mesenchymal cell to an epithelial cell resulting in the epithelial cell adopting the identity of a cell of the mammary placode.


name: relaxation of vascular associated smooth muscle

description: A negative regulation of smooth muscle contraction resulting in relaxation of vascular smooth muscle. The relaxation is mediated by a decrease in the phosphorylation state of myosin light chain. This can be achieved by removal of calcium from the cytoplasm to the sarcoplasmic reticulum lumen through the action of Ca2+ ATPases leading to a decrease myosin light chain kinase activity, and through calcium-independent pathways leading to a increase in myosin light chain phosphatase activity.


neuropeptide F receptor activity

description: Combining with neuropeptide F and transmitting the signal within the cell to initiate a change in cell activity. Neuropeptide F is an arthropod peptide of more than 28 residues (typically 28-45) with a consensus C-terminal RxRFamide (commonly RPRFa, but also RVRFa.


rhamnogalacturonan II metabolic process

description: The chemical reactions and pathways involving rhamnogalacturonan II, a low molecular mass (5-10KDa) pectic polysaccharide. The backbone of RG-II contains at least 8 1,4-linked alpha-D-GalpA residues.


pyoverdine biosynthetic process

description: The chemical reactions and pathways resulting in the formation of the siderochrome pyoverdine.


name: regulation of somatic muscle development

description: Any process that regulates the rate, frequency or extent of somatic muscle development.


cobalt ion binding

description: Binding to a cobalt ion (Co2+).


2-oxo-acid reductase activity

description: Catalysis of the reaction: a (2R)-hydroxy-carboxylate + acceptor = a 2-oxo-carboxylate + reduced acceptor.


name: negative regulation of alcohol biosynthetic process

description: Any process that stops, prevents or reduces the frequency, rate or extent of alcohol biosynthetic process.


regulation of cholesterol import

description: Any process that modulates the rate, frequency or extent of cholesterol import. Cholesterol import is the directed movement of cholesterol into a cell or organelle.


glycolate metabolic process

description: The chemical reactions and pathways involving glycolate, the anion of hydroxyethanoic acid (glycolic acid).


interleukin-17 receptor activity

description: Combining with any member of the interleukin-17 family of cytokines and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


name: tolerance induction in gut-associated lymphoid tissue

description: Tolerance induction taking place in the gut-associated lymphoid tissue (GALT).


raucaffricine beta-glucosidase activity

description: Catalysis of the reaction: H2O + raucaffricine = D-glucose + vomilenine.


description: Catalysis of the reaction: isovitexin + UDP-D-glucose = H+ + isovitexin 2''-O-beta-D-glucoside + UDP.


name: negative regulation of cartilage condensation

description: Any process that stops, prevents or reduces the frequency, rate or extent of cartilage condensation.


regulation of renal water transport

description: Any process that modulates the frequency, rate or extent of renal water transport.


fructan biosynthetic process

description: The chemical reactions and pathways resulting in the formation of fructan a polysaccharide consisting of fructose residues.


regulation of developmental growth

description: Any process that modulates the frequency, rate or extent of developmental growth.


cardiolipin synthase (CMP-forming)

description: Catalysis of the reaction: CDP-diacylglycerol + phosphatidylglycerol = CMP + diphosphatidylglycerol.


name: beta-hydroxybutyrate transmembrane transporter activity

description: Enables the transfer of beta-hydroxybutyrate from one side of a membrane to the other. Beta-hydroxybutyrate is the conjugate base of (R)-3-hydroxybutyric acid.


vacuolar localization

description: Any process in which the vacuole is transported to, and/or maintained in, a specific location within the cell.


name: negative regulation of RNA-dependent RNA polymerase activity

description: Any process that stops, prevents or reduces the frequency, rate or extent of RNA-directed 5'-3' RNA polymerase activity.


nephron morphogenesis

description: The process in which the anatomical structures of the nephron are generated and organized. A nephron is the functional unit of the kidney.


nucleobase catabolic process

description: The chemical reactions and pathways resulting in the breakdown of a nucleobase, a nitrogenous base that is a constituent of a nucleic acid.


name: positive regulation of adenosine receptor signaling pathway

description: Any process that activates or increases the frequency, rate or extent of the adenosine receptor signaling pathway. The adenosine receptor pathway is the series of molecular signals generated as a consequence of an adenosine receptor binding to one of its physiological ligands.


streptomycin metabolic process

description: The chemical reactions and pathways involving streptomycin, a commonly used antibiotic in cell culture media. It acts only on prokaryotes and blocks transition from initiation complex to chain elongating ribosome.


pyridine biosynthetic process

description: The chemical reactions and pathways resulting in the formation of pyridine, a nitrogenous base (C5H5N) obtained from the distillation of bone oil or coal tar, and by the decomposition of certain alkaloids, as a colorless liquid with a peculiar pungent odor.


spindle pole body anchor activity

description: The binding activity of a protein that brings together the spindle pole body and one or more other molecules, permitting them to function in a coordinated way.


description: Catalysis of the reaction: 2-polyprenyl-6-hydroxyphenol + S-adenosyl-L-methionine = 2-polyprenyl-6-methoxyphenol + S-adenosyl-L-homocysteine + H+.


name: SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition

description: The process in which SRP binds to the signal peptide in a nascent protein, causing protein elongation to pause, during cotranslational membrane targeting.


glucuronoside metabolic process

description: The chemical reactions and pathways involving glucuronosides, any compound formed by combination in glycosidic linkage of a hydroxy compound with the anomeric carbon atom of a glucuronate.


regulation of lateral root development

description: Any process that modulates the frequency, rate or extent of lateral root development.


monocyte extravasation

description: The migration of a monocyte from the blood vessels into the surrounding tissue.


name: pyrimidine dimer repair by nucleotide-excision repair

description: The repair of UV-induced T-T, C-T, and C-C dimers by the recognition and removal of the damaged DNA strand from the DNA helix as an oligonucleotide. The small gap left in the DNA helix is filled in by the sequential action of DNA polymerase and DNA ligase.


description: Catalysis of the reaction: 5-dehydro-4-deoxy-D-glucarate + H+ = 2,5-dioxopentanoate + CO2 + H2O.


cellular response to flavonoid

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a flavonoid stimulus.


macrolide binding

description: Binding to a macrolide, any of a large group of structurally related antibiotics produced by Streptomyces species.


instar larval or pupal morphogenesis

description: The process, occurring during instar larval or pupal development, by which anatomical structures are generated and organized.


name: protein folding in endoplasmic reticulum

description: A protein folding process that takes place in the endoplasmic reticulum (ER). Secreted, plasma membrane and organelle proteins are folded in the ER, assisted by chaperones and foldases (protein disulphide isomerases), and additional factors required for optimal folding (ATP, Ca2+ and an oxidizing environment to allow disulfide bond formation).


putrescine binding

description: Binding to putrescine, 1,4-diaminobutane, the polyamine formed by decarboxylation of ornithine and the metabolic precursor of spermidine and spermine.


name: glutathione-disulfide reductase (NADPH) activity

description: Catalysis of the reaction: 2 glutathione + NADP+ = glutathione disulfide + NADPH + H+.


name: response to rest involved in regulation of muscle adaptation

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a rest stimulus. This process occurs as part of the regulation of muscle adaptation.


P-type magnesium transporter activity

description: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Mg2+(out) = ADP + phosphate + Mg2+(in).


description: Catalysis of the reaction: cystine + 2 reduced glutathione = oxidized glutathione + 2 L-cysteine.


stipitatonate decarboxylase activity

description: Catalysis of the reaction: H2O + stipitatonate = CO2 + H+ + stipitatate.


3-isopropylmalate dehydratase activity

description: Catalysis of the reaction: (2R,3S)-3-isopropylmalate = (2S)-2-isopropylmalate.


name: regulation of locomotion involved in locomotory behavior

description: Any process that modulates the frequency, rate, or extent of the self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement.


name: negative regulation of humoral immune response

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of a humoral immune response.


name: bicyclic nitroimidazole metabolic process

description: The chemical reactions and pathways involving bicyclic nitroimidazoles, imidazole derivatives with two rings and a nitro group attached to one ring.


description: Catalysis of the reaction: acetyl-CoA + gentamicin C(1a) = N(2')-acetylgentamicin C(1a) + CoA + H+. This is acetylation of the 2'-amino group of the 6-deoxy-6-aminoglucose ring.


name: optic cup formation involved in camera-type eye development

description: The developmental process pertaining to the initial formation of the optic cup, a two-walled vesicle formed from the optic vesicle.


name: oxidative stress-induced premature senescence

description: A cellular senescence process associated with the dismantling of a cell as a response to oxidative stress, e.g. high levels of reactive oxygen species, such as superoxide anions, hydrogen peroxide, and hydroxyl radicals.


name: cysteine biosynthetic process via S-sulfo-L-cysteine

description: The chemical reactions and pathways resulting in the formation of cysteine, via the intermediate S-sulfo-L-cysteine.


description: The chemical reactions and pathways resulting in the breakdown of (17Z)-protosta-17(20),24-dien-3beta-ol.


name: positive regulation of transforming growth factor beta receptor signaling pathway

description: Any process that activates or increases the frequency, rate or extent of TGF-beta receptor signaling pathway activity.


name: methylenetetrahydrofolate reductase (ferredoxin) activity

description: Catalysis of the reaction: 5-methyltetrahydrofolate + oxidized ferredoxin = 5,10-methylenetetrahydrofolate + reduced ferredoxin.


name: positive regulation of DNA-templated DNA replication

description: Any process that activates or increases the frequency, rate or extent of DNA-templated DNA replication.


cellular response to resveratrol

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a resveratrol stimulus.


name: negative regulation of prostaglandin catabolic process

description: Any process that stops, prevents or reduces the frequency, rate or extent of prostaglandin catabolic process.


name: negative regulation of growth hormone receptor signaling pathway

description: Any process that decreases the rate, frequency or extent of the growth hormone receptor signaling pathway. The growth hormone receptor signaling pathway is the series of molecular signals generated as a consequence of growth hormone receptor binding to its physiological ligand.


interleukin-16 production

description: The appearance of interleukin-16 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


selenomethionine-tRNA ligase activity

description: Catalysis of the reaction: ATP + L-selenomethionine + tRNA(Met) => AMP + diphosphate + selenomethionyl-tRNA(Met).


bradykinin catabolic process

description: The chemical reactions and pathways resulting in the breakdown of the peptide bradykinin.


sperm plasma membrane disassembly

description: The gradual disintegration of the sperm plasma membrane following insemination. This process is seen in Drosophila after entry of the entire sperm, surrounded by its plasma membrane, into the egg.


name: regulation of somitomeric trunk muscle development

description: Any process that modulates the frequency, rate or extent of somitomeric trunk muscle development.


U6 snRNA binding

description: Binding to a U6 small nuclear RNA (U6 snRNA).


GUU codon-amino acid adaptor activity

description: A triplet codon-amino acid adaptor activity that recognizes a GUU codon.


name: regulation of signal transduction involved in conjugation with cellular fusion

description: Any process that modulates the rate, frequency or extent of pheromone-dependent signal transduction during conjugation with cellular fusion.


B-1 B cell proliferation

description: The expansion of a B-1 B cell by cell division. Follows B cell activation.


interleukin-37 production

description: The appearance of interleukin-37 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


name: acetyl-CoA:oxalate CoA-transferase

description: Catalysis of the reaction: acetyl-CoA + oxalate = acetate + oxalyl-CoA.


name: mitochondrion-plasma membrane adaptor activity

description: The binding activity of a molecule that brings together a mitochondrion and a plasma membrane either via membrane lipid binding or by interacting with a mitochondrial outer membrane protein, to establish or maintain the localization of the mitochondrion.


name: organic heteropentacyclic compound catabolic process

description: The chemical reactions and pathways resulting in the breakdown of organic heteropentacyclic compound.


IDP catabolic process

description: The chemical reactions and pathways resulting in the breakdown of IDP, inosine 5'-diphosphate.


dUTP metabolic process

description: The chemical reactions and pathways involving dUTP, deoxyuridine (5'-)triphosphate.


peptidyl-lysine dimethylation

description: The methylation of peptidyl-lysine to form peptidyl-N6,N6-dimethyl-L-lysine.


name: negative regulation of chondrocyte proliferation

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the multiplication or reproduction of chondrocytes by cell division, resulting in the expansion of their population. A chondrocyte is a polymorphic cell that forms cartilage.


description: Catalysis of the reaction: (S)-3-methyl-2-oxopentanoate + L-valine = 3-methyl-2-oxobutanoate + L-isoleucine.


auxin-activated signaling pathway

description: The series of molecular signals generated by the binding of the plant hormone auxin to a receptor, and ending with modulation of a downstream cellular process, e.g. transcription.


name: mesenchymal smoothened signaling pathway involved in prostate gland development

description: The series of molecular signals generated as a consequence of activation of the transmembrane Smoothened-type protein in the mesenchymal cells of the prostate that contribute to the progression of the prostate over time. This process contributes to lung development.


cytidine salvage

description: Any process that generates cytidine, cytosine riboside, from derivatives of it without de novo synthesis.


ornithine N5-monooxygenase activity

description: Catalysis of the reaction: L-ornithine + O2 + H+ = N5-hydroxy-L-ornithine + H2O.


atrioventricular valve morphogenesis

description: The process in which the structure of the atrioventricular valve is generated and organized.


betaine reductase activity

description: Catalysis of the reaction: [thioredoxin]-disulfide + acetyl phosphate + H2O + trimethylamine = [thioredoxin]-dithiol + glycine betaine + H+ + phosphate.


name: positive regulation of flavonoid biosynthetic process

description: Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of flavonoids.


lobar bronchus development

description: The biological process whose specific outcome is the progression of a lobar bronchus from an initial condition to its mature state. This process begins with the formation of the lobar bronchus and ends with the mature structure. The lobar bronchus is the major airway within the respiratory tree that starts by division of the principal bronchi on both sides and ends at the point of its own subdivision into tertiary or segmental bronchi.


name: positive regulation by virus of viral protein levels in host cell

description: Any process where the infecting virus increases the levels of viral proteins in a cell.


signal recognition particle binding

description: Binding to a signal recognition particle.


name: regulation of horizontal cell localization

description: Any process that modulates the frequency, rate or extent of horizontal cell localization.


multinuclear osteoclast differentiation

description: The process in which a relatively unspecialized monocyte acquires the specialized features of a multinuclear osteoclast. An osteoclast is a specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue.


name: positive regulation of ribosomal large subunit export from nucleus

description: Any process that activates or increases the frequency, rate or extent of ribosomal large subunit export from nucleus.


description: Catalysis of the reaction: 5-hydroxypentanoate + acetyl-CoA = 5-hydroxy-pentanoyl-CoA + acetate.


podocyte cell migration

description: The orderly movement of a podocyte from one site to another, often during the development of a multicellular organism or multicellular structure. A podocyte is a specialized kidney epithelial cell.


lithocholate 6beta-hydroxylase activity

description: Catalysis of the reaction: H+ + lithocholate + NADPH + O2 = 6-beta-hydroxylithocholate + H2O + NADP+.


perithecium formation

description: The process of producing flask-shaped fruiting bodies, called perithecia. In the ascomycetous fungi such as Neurospora crassa and Sordaria macrospora, these perithecia are formed in the sexual phase and they discharge ascospores through the ostiolum at the tip of the perithecial neck.


name: secondary active cyanate transmembrane transporter activity

description: Enables the transfer of cyanate from one side of a membrane to the other.


N-acetylcitrulline deacetylase activity

description: Catalysis of the reaction: N-acetyl-L-citrulline + H2O = citrulline + acetate.


name: negative regulation of hemocyte proliferation

description: Any process that stops, prevents or reduces the rate or extent of hemocyte proliferation. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. An example of this is found in Drosophila melanogaster.


description: Catalysis of the hydrolysis of (1->2) and (1->3) linkages in mannan, releasing mannose.


name: positive regulation of neutrophil mediated killing of gram-negative bacterium

description: Any process that increases the frequency, rate or extent of the directed killing of a gram-negative bacterium by a neutrophil.


name: negative regulation of cell wall organization or biogenesis

description: Any process that stops, prevents or reduces the frequency, rate or extent of cell wall organization or biogenesis.


thiocyanate catabolic process

description: The chemical reactions and pathways resulting in the breakdown of thiocyanate, any anion of thiocyanic acid.


blood vessel lumenization

description: The process in which a developing blood vessel forms an endothelial lumen through which blood will flow.


sesquisabinene synthase activity

description: Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate(3-) = diphosphoric acid + sesquisabinene.


aldehyde-lyase activity

description: Catalysis of the cleavage of a C-C bond in a molecule containing a hydroxyl group and a carbonyl group to form two smaller molecules, each being an aldehyde or a ketone.


post-embryonic anal fin morphogenesis

description: The process, occurring after embryonic development, by which the anatomical structures of the anal fin are generated and organized. An anal fin is an unpaired medial fin on the ventral aspect near the caudal end of a fish, which provides lateral stability while swimming.