name: plasma membrane electron transport, NADH to quinone

description: The transfer of electrons from NADH to the quinone pool that occurs during oxidative phosphorylation and results in the generation of a proton gradient, mediated by the enzyme known as NADH-quinone oxidoreductase.


emericellamide A biosynthetic process

category: biolink:BiologicalProcess biolink:Occurrent biolink:OntologyClass biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: The chemical reactions and pathways resulting in the formation of emericellamide A.


formaldehyde biosynthetic process

description: The chemical reactions and pathways resulting in the formation of formaldehyde (methanal, H2C=O), the simplest aldehyde.


glutamine metabolic process

description: The chemical reactions and pathways involving glutamine, 2-amino-4-carbamoylbutanoic acid.


name: regulation of pyruvate dehydrogenase activity

description: Any process that modulates the frequency, rate or extent of pyruvate dehydrogenase activity.


naphthalene 1,2-dioxygenase activity

category: biolink:MolecularActivity biolink:Occurrent biolink:OntologyClass biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: Catalysis of the reaction: naphthalene + NADH + H+ + O2 = (1R,2S)-1,2-dihydronaphthalene-1,2-diol + NAD+.


description: Catalysis of the movement of N-retinylidene-N-retinylphosphatidylethanolamine from the exoplasmic to the cytosolic leaftlet of a membrane, using energy from the hydrolysis of ATP.


cell adhesion molecule production

description: The appearance of a cell adhesion molecule due to biosynthesis or secretion.


methanethiol oxidase activity

description: Catalysis of the reaction: methanethiol + O2 + H2O = formaldehyde + hydrogen sulfide + hydrogen peroxide.


RNA pseudouridylation guide activity

description: Specifies the site of pseudouridylation in an RNA molecule by base pairing with a short sequence around the target residue.


peptidyl-proline 4-dioxygenase activity

description: Catalysis of the reaction: peptidyl L-proline + 2-oxoglutarate + O2 = peptidyl trans-4-hydroxy-L-proline + succinate + CO2.


description: Catalysis of the reaction: (R)-3-hydroxybutanoate + NAD+ = acetoacetate + H+ + NADH.


description: Catalysis of the reaction: 2-ketocyclohexane-1-carboxyl-CoA + H2O = pimeloyl-CoA.


sensory neuron migration

description: The orderly movement of a sensory neuron from one site to another.


name: 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase activity from histidine and PLP

description: Catalysis of the reaction: 2 Fe(3+) + 4 H2O + L-histidyl-[4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase] + N(6)-(pyridoxal phosphate)-L-lysyl-[4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase] = (2S)-2-amino-5-hydroxy-4-oxopentanoyl-[4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase] + 3-oxopropanoate + 4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine + 2 Fe(2+) + 2 H+ + L-lysyl-[4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase].


description: Catalysis of the reaction: DNA containing 7-methylguanine + H2O = DNA with abasic site + 7-methylguanine. This reaction is the hydrolysis of DNA by cleavage of the N-C1' glycosidic bond between the damaged DNA 7-methylguanine and the deoxyribose sugar to remove the 7-methylguanine, leaving an abasic site.


aerobactin biosynthetic process

description: The chemical reactions and pathways resulting in the formation of aerobactin (C22H36N4O13), a hydroxamate iron transport compound. It is a conjugate of 6-(N-acetyl-N-hydroxylamine)-2-aminohexanoic acid and citric acid.


name: regulation of oligodendrocyte progenitor proliferation

description: Any process that modulates the frequency, rate or extent of oligodendrocyte progenitor proliferation.


steroid dehydrogenase activity

description: Catalysis of an oxidation-reduction (redox) reaction in which one substrate is a sterol derivative.


indole glucosinolate catabolic process

description: The chemical reactions and pathways resulting in the breakdown of indole glucosinolates, sulfur-containing compounds that have a common structure linked to an R group derived from tryptophan.


polyol catabolic process

description: The chemical reactions and pathways resulting in the breakdown of a polyol, any alcohol containing three or more hydroxyl groups attached to saturated carbon atoms.


description: Catalysis of the reaction: 1,1-dichloro-2-(dihydroxy-4'-chorophenyl)-2-(4-chlorophenyl)ethene + O2 = 6-oxo-2-hydroxy-7-(4-chlorophenyl)-3,8,8-trichloroocta-2E,4E,7-trienoate.


name: hypothalamus gonadotrophin-releasing hormone neuron development

description: The process whose specific outcome is the progression of a hypothalamus gonadotrophin-releasing hormone neuron over time, from initial commitment of its fate, to the fully functional differentiated cell.


name: high-affinity glucose transmembrane transporter activity

description: Enables the transfer of glucose from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.


response to vanadate(3-)

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vanadate(3-) stimulus.


name: isopeptide cross-linking via N-(L-isoglutamyl)-glycine

description: The formation of an isopeptide cross-link between peptidyl-glutamate and peptidyl-glycine to produce N-(L-isoglutamyl)-glycine, as found in the antibiotic microcin J25.


dAMP binding

description: Binding to dAMP, deoxyadenosine monophosphate.


lung goblet cell differentiation

description: The process in which a relatively unspecialized cell acquires specialized features of a lung goblet cell. A goblet cell is a cell of the epithelial lining that produces and secretes mucins.


alcohol O-butanoyltransferase activity

description: Catalysis of the reaction: butanoyl-CoA + an alcohol = CoA + a butyl ester.


centrolateral pattern formation

description: The regionalization process in which the areas along the centrolateral axis are established that will lead to differences in cell differentiation, or in which cells interpret a specific environment.


name: cellular response to dehydroepiandrosterone

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dehydroepiandrosterone stimulus.


name: paraxial mesodermal cell fate specification

description: The process in which a cell becomes capable of differentiating autonomously into a paraxial mesoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.


name: negative regulation of cardiac cell fate specification

description: Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac cell fate specification.


name: glutathione-regulated potassium exporter activity

description: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: K+(in) + H+(out) = K+(out) + H+(in), where glutathione maintains the closed state.


lateral reticular nucleus development

description: The process whose specific outcome is the progression of the lateral reticular nucleus over time, from its formation to the mature structure.


archaeosine-tRNA biosynthetic process

description: The chemical reactions and pathways involved in the biosynthesis of archaeosine, an archaea-specific modified base found at position 15 in the D-loop of certain archaeal tRNAs.


name: fungal-type cell wall beta-glucan metabolic process

description: The chemical reactions and pathways involving beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of fungal cells.


N-cyclopropylmelamine catabolic process

description: The chemical reactions and pathways resulting in the breakdown of N-cyclopropylmelamine, a triazine compound commonly used as an insecticide.


plasma membrane invagination

description: An infolding of the plasma membrane.


auxin metabolic process

description: The chemical reactions and pathways involving auxins, a group of plant hormones that regulate aspects of plant growth.


name: positive regulation of muscle adaptation

description: Any process that activates or increases the frequency, rate or extent of muscle adaptation.


name: 2,4,5-trichlorophenoxyacetic acid catabolic process

description: The chemical reactions and pathways resulting in the breakdown of 2,4,5-trichlorophenoxyacetic acid, a chlorinated aromatic compound widely used as a herbicide.


name: cellular detoxification of methylglyoxal

description: Any process carried out at the cellular level that reduces or removes the toxicity of methylglyoxal. These may include chemical modification or transport of methylglyoxal away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance.


glycosphingolipid metabolic process

description: The chemical reactions and pathways involving glycosphingolipids, any compound with residues of sphingoid and at least one monosaccharide.


description: Catalysis of the reaction: S-adenosyl-L-methionine + (RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline = S-adenosyl-L-homocysteine + N-methyl-(RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline.


name: negative regulation of netrin-activated signaling pathway

description: Any process that stops, prevents or reduces the frequency, rate or extent of netrin-activated signaling pathway.


prenylation

description: The covalent attachment of a prenyl group to a molecule; geranyl, farnesyl, or geranylgeranyl groups may be added.


mammary gland bud morphogenesis

description: The process in which anatomical structures of the mammary gland buds are generated and organized. Mammary gland buds form by an outpocketing of the mammary placodes and grow to invade the mammary fat, when they form the mammary cord.


5-epi-aristolochene synthase activity

description: Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = (+)-5-epi-aristolochene + diphosphoric acid.


name: positive regulation of MDA-5 signaling pathway

description: Any process that activates or increases the frequency, rate or extent of MDA-5 signaling pathway.


beta-D-fucosidase activity

description: Catalysis of the hydrolysis of terminal non-reducing beta-D-fucose residues in beta-D-fucosides.


iron-sulfur-molybdenum cofactor binding

description: Binding to iron molybdenum cofactor, the cofactor located at the active site of the molybdenum nitrogenase.


metanephric glomerulus development

description: The progression of the metanephric glomerulus over time from its initial formation until its mature state. The metanephric glomerulus is a capillary tuft which forms a close network with the visceral epithelium (podocytes) and the mesangium to form the filtration barrier and is surrounded by Bowman's capsule in nephrons of the mature vertebrate kidney, or metanephros.


cholecystokinin signaling pathway

category: biolink:Pathway biolink:OntologyClass biolink:BiologicalProcess biolink:Occurrent biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: A G protein-coupled receptor signaling pathway initiated by cholecystokinin binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.


name: acrylate:acyl-coA CoA transferase activity

description: Catalysis of the reaction: acryloyl-CoA + H2O = acrylate + coenzyme A + H+.


description: Catalysis of the reaction: (R)-noradrenaline + L-glutaminyl-[protein] = 5-(R)-noradrenalinyl-L-glutamyl-[protein] + NH4(+).


name: mitochondrial ribosomal large subunit rRNA binding

description: Binding to a mitochondrial large ribosomal subunit RNA (LSU rRNA).


miRNA transcription

description: The cellular synthesis of microRNA (miRNA) transcripts. MicroRNA genes are synthesized as primary (pri) miRNA transcripts and subsequently processed to produce the ~22nt miRNAs that function in gene regulation.


name: positive regulation of somatic muscle development

description: Any process that increases the rate, frequency or extent of somatic muscle development.


name: triplet codon-amino acid adaptor activity

description: The codon binding activity of a tRNA that positions an activated amino acid, mediating its insertion at the correct point in the sequence of a nascent polypeptide chain during protein synthesis.


name: regulation of cellotriose metabolic process

description: Any process that modulates the frequency, rate or extent of cellotriose metabolic process.


name: positive regulation of cell proliferation in bone marrow

description: A process that activates or increases the frequency, rate or extent of cell proliferation in the bone marrow.


regulation of intestinal absorption

description: Any process that modulates the frequency, rate or extent of intestinal absorption.


name: negative regulation of lens epithelial cell proliferation

description: Any process that stops, prevents or reduces the frequency, rate or extent of lens epithelial cell proliferation.


p-cymene methyl hydroxylase activity

description: Catalysis of the reaction: p-cymene + NADH + O2 = NAD+ + OH- + p-cumic alcohol.


name: keto-3-deoxy-D-manno-octulosonic acid biosynthetic process

description: The chemical reactions and pathways resulting in the formation of keto-3-deoxy-D-manno-octulosonic acid, an acidic sugar present in lipopolysaccharides of the outer membranes of some Gram-negative bacteria.


name: negative regulation of atrial cardiac muscle cell action potential

description: Any process that stops, prevents or reduces the frequency, rate or extent of atrial cardiac muscle cell action potential.


description: Catalysis of the reaction: O-acetyl-L-homoserine + hydrogen sulfide = homocysteine + acetate.


name: voltage-gated calcium channel complex assembly

description: Cellular protein complex assembly that results in the formation of a voltage-gated calcium channel complex.


positive regulation of ferroptosis

description: Any process that activates or increases the frequency, rate or extent of ferroptosis.


name: endodermal digestive tract morphogenesis

description: The process in which the anatomical structures of the endodermal digestive tract are generated and organized. The endodermal digestive tract includes those portions of the digestive tract that are derived from endoderm.


natural killer cell differentiation

description: The process in which a relatively unspecialized cell acquires the specialized features of a natural killer cell.


1,3-propanediol dehydrogenase activity

description: Catalysis of the reaction: propane-1,3-diol + NAD+ = 3-hydroxypropanal + NADH + H+.


name: intramembrane lipid transporter activity

description: Enables the transport of a lipid from a region of a membrane to a different region on the same membrane.


dihydropterin oxidase activity

description: Catalysis of the reaction: a 7,8-dihydropteridine + O2 = a pterin + hydrogen peroxide.


name: protein-N(PI)-phosphohistidine-glucose phosphotransferase system transporter activity

description: Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + glucose(out) = protein histidine + glucose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.


name: modulation of heart rate in another organism

description: Any process that modulates the frequency or rate of heart contraction of another organism.


name: regulation of octopamine signaling pathway

description: Any process that modulates the frequency, rate or extent of octopamine signaling pathway.


proximal tubule morphogenesis

description: The process in which the anatomical structures of a proximal tubule are generated and organized. The proximal tubule is a nephron tubule that connects Bowman's capsule to the descending thin limb of the loop of Henle. It has a brush border epithelial morphology.


name: negative regulation of cell wall polysaccharide catabolic process

description: Any process that stops, prevents or reduces the frequency, rate or extent of cell wall polysaccharide catabolic process.


name: negative regulation of sphingolipid mediated signaling pathway

description: Any process that stops, prevents or reduces the frequency, rate or extent of sphingolipid signaling.


description: Catalysis of the reaction: retinol-[cellular-retinol-binding-protein] + phosphatidylcholine = retinyl-ester-[cellular-retinol-binding-protein] + 2-acylglycerophosphocholine.


negative regulation of fibrinolysis

description: Any process that stops, prevents, or reduces the frequency, rate or extent of fibrinolysis, an ongoing process that solubilizes fibrin, resulting in the removal of small blood clots.


name: cellular response to prostaglandin F stimulus

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin F stimulus.


name: positive regulation of compound eye photoreceptor cell differentiation

description: Any process that activates or increases the frequency, rate or extent of compound eye photoreceptor cell differentiation.


C-terminal protein methylation

description: The methylation of the C-terminal amino acid of a protein.


mesangial cell development

description: The process whose specific outcome is the progression of a mesangial cell in the kidney over time, from its formation to the mature structure.


name: synaptic vesicle fusion to presynaptic active zone membrane

description: Fusion of the membrane of a synaptic vesicle with the presynaptic active zone membrane, thereby releasing its cargo neurotransmitters into the synaptic cleft.


RNA polymerase III promoter clearance

description: A process that mediates the transition from the initiation to the elongation phases of transcription by RNA polymerase III, generally including a conformational change from the initiation conformation to the elongation conformation. Promoter clearance often involves breaking contact with transcription factors involved only in the initiation phase.


name: regulation of prostaglandin-endoperoxide synthase activity

description: Any process that modulates the rate, frequency or prostaglandin-endoperoxide synthase activity. Prostaglandin-endoperoxide synthase activity is the catalysis of the reaction: arachidonate + donor-H2 + 2 O2 = prostaglandin H2 + acceptor + H2O.


description: The chemical reactions and pathways resulting in the formation of (17Z)-protosta-17(20),24-dien-3beta-ol.


name: positive regulation of membrane potential

description: Any process that activates or increases the frequency, rate or extent of establishment or extent of a membrane potential, the electric potential existing across any membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane.


L-altrarate metabolic process

description: The chemical reactions and pathways involving L-altrarate.


name: positive regulation of larval somatic muscle development

description: Any process that increases the rate, frequency or extent of larval somatic muscle development.


limb morphogenesis

description: The process in which the anatomical structures of a limb are generated and organized. A limb is a paired appendage of a tetrapod used for locomotion or grasping.


response to tamsulosin

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tamsulosin stimulus.


cocaine metabolic process

description: The chemical reactions and pathways involving cocaine, an alkaloid obtained from the dried leaves of the shrub Erythroxylon coca. It is a cerebral stimulant and narcotic.


absorption of visible light

description: The reception of a (visible light) photon by a cell, visible light being defined as having a wavelength within the range 380-780 nm.


name: regulation of synaptic signaling by nitric oxide

description: Any process that modulates the frequency, rate or extent of synaptic signaling by nitric oxide.


eosinophil migration

description: The movement of an eosinophil within or between different tissues and organs of the body.


auxin binding

description: Binding to auxin, a plant hormone that regulates aspects of plant growth.


stereocilium maintenance

description: The organization process that preserves a stereocilium in a stable functional or structural state.


name: negative regulation of ascospore formation

description: Any process that stops, prevents, or reduces the frequency, rate or extent of ascospore formation, a process in which a sexual spore, named ascospore, from Ascomycete fungi was produced inside an ascus.


name: midbrain-hindbrain boundary maturation during neural plate development

description: A developmental process occurring before the brain has been specified along the neural axis that is required for the midbrain-hindbrain boundary to attain its fully functional state. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate.


adenosylcobinamide hydrolase activity

description: Catalysis of the reaction: adenosylcobinamide + H2O = (R)-1-aminopropan-2-ol + adenosylcobyrate.


name: regulation of lipopolysaccharide-mediated signaling pathway

description: Any process that modulates the frequency, rate or extent of signaling in response to detection of lipopolysaccharide.


fraxetin biosynthesis

description: The chemical reactions and pathways resulting in the formation of fraxetin.


RNA cytidine insertion

description: The modification of an RNA molecule by insertion of a cytidine nucleotide.


steroid hormone biosynthetic process

description: The chemical reactions and pathways resulting in the formation of any steroid hormone, naturally occurring substances secreted by specialized cells that affects the metabolism or behavior of other cells possessing functional receptors for the hormone.


name: antigen processing and presentation following receptor mediated endocytosis

description: Antigen processing and presentation which is initiated by uptake of antigen receptor-mediated endocytosis.


teichuronic acid biosynthetic process

description: The chemical reactions and pathways resulting in the formation of teichuronic acid, a polymer containing chains of uronic acids and N-acetylglucosamine found in the cell wall, membrane or capsule of Gram-positive bacteria.


phasic smooth muscle contraction

description: A process in which force is generated within phasic smooth muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. In the phasic smooth muscle, the muscle contraction occurs without an ordered sarcomeric structure. Phasic smooth muscle contraction occurs in a series of discrete contractions and relaxations.


tyrosine-arginine ligase activity

description: Catalysis of the reaction: L-arginine + L-tyrosine + ATP = L-tyrosyl-L-arginine + AMP + diphosphate + 2 H+.


description: Catalysis of the reaction: 3D-3,5/4-trihydroxycyclohexane-1,2-dione + H2O = 5-deoxy-D-glucuronate + H+.


name: regulation of tonic skeletal muscle contraction

description: Any process that modulates the frequency, rate or extent of tonic skeletal muscle contraction.


name: mesonephric proximal tubule morphogenesis

description: The process in which the anatomical structures of a mesonephric proximal tubule are generated and organized. The mesonephric proximal tubule extends from the capsule to the distal tubule.


negative regulation of ossification

description: Any process that stops, prevents, or reduces the frequency, rate or extent of ossification, the formation of bone or of a bony substance or the conversion of fibrous tissue or of cartilage into bone or a bony substance.


internal protein amino acid acetylation

description: The addition of an acetyl group to a non-terminal amino acid in a protein.


name: negative regulation of cell adhesion in ventricular zone

description: The process that results in the loss of attachments of a cell in the ventricular zone.


description: Catalysis of the reaction: 3',3'-c-di-AMP + H2O = 5'-O-phosphonoadenylyl-(3'-5')-adenosine + H+.


description: Catalysis of the reaction: (2S,3R,4S)-4-hydroxy-L-isoleucine + NAD = (2S,3R)-2-amino-3-methyl-4-ketopentanoate + NADH + H+.


description: Catalysis of the reaction: 6-hydroxy-3-succinoylpyridine + H2O = succinic semialdehyde + 2,5-dihydroxypyridine.


regulation of ethanol catabolic process

description: Any process that modulates the frequency, rate or extent of ethanol catabolic process.


cellular response to glyoxal

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glyoxal stimulus.


name: mechanosensitive voltage-gated sodium channel activity

description: Enables the transmembrane transfer of a sodium ion by a voltage-gated channel whose activity is modulated in response to mechanical stress. Response to mechanical stress and voltage gating together is different than the sum of individual responses. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.


name: regulation of neutrophil mediated killing of fungus

description: Any process that modulates the rate, frequency or extent of neutrophil mediated killing of a fungal cell, the directed killing of a fungal cell by a neutrophil.


protein localization to meiotic spindle

description: A process in which a protein is transported to, or maintained in, a location within a meiotic spindle.


fructoselysine biosynthetic process

description: The chemical reactions and pathways resulting in the formation of fructoselysine.


name: negative regulation of lymphocyte anergy

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of lymphocyte anergy.


RNA cytidine-uridine insertion

description: The modification of an RNA molecule by insertion of an cytidine-uridine dinucleotide.


name: nuclear polyadenylation-dependent ncRNA catabolic process

description: The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of a noncoding RNA (ncRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target ncRNA.


name: establishment of synaptic vesicle localization

description: The directed movement of a synaptic vesicle or vesicles to a specific location.


name: positive regulation of cerebral blood circulation

description: Any process that activates or increases the frequency, rate or extent of cerebral blood circulation.


name: protocatechuate catabolic process, ortho-cleavage

description: The chemical reactions and pathways resulting in the breakdown of protocatechuate, the anion of 3,4-dihydroxybenzoic acid, to yield beta-ketoadipate.


name: neuronal stem cell population maintenance

description: Any process in by an organism or tissue maintains a population of neuronal stem cells.


myosuppressin receptor activity

description: Combining with the peptide myosuppressin to initiate a change in cell activity.


description: Catalysis of the reaction: 7,8-dihydroneopterin triphosphate + H2O = 6-carboxy-5,6,7,8-tetrahydropterin + triphosphate + acetaldehyde + 2 H+.


name: platelet-derived growth factor beta-receptor activity

description: Combining with platelet-derived growth factor isoform PDGF-BB or PDGF-AB to initiate a change in cell activity.


urate oxidase activity

description: Catalysis of the reaction: urate + O2 + H2O = 5-hydroxyisourate + hydrogen peroxide.


name: negative regulation of R7 cell fate commitment

description: Any process that stops, prevents or reduces the frequency, rate or extent of R7 cell fate commitment.


name: negative regulation of mesenchymal cell proliferation

description: Any process that decreases the frequency, rate or extent of mesenchymal cell proliferation. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets.


name: positive regulation of alcohol biosynthetic process

description: Any process that activates or increases the frequency, rate or extent of alcohol biosynthetic process.


cloacal gland development

description: The process whose specific outcome is the progression of a cloacal gland over time, from its formation to the mature structure.


name: metanephric glomerular mesangial cell differentiation

description: The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the glomerular mesangial cells of the metanephros as it progresses from its formation to the mature state.


name: monocyte antigen processing and presentation

description: The process in which a monocyte expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex.


ABC-type nickel transporter activity

description: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Ni2+(out) = ADP + phosphate + Ni2+(in).


parallel actin filament bundle assembly

description: Assembly of actin filament bundles in which the filaments are tightly packed (approximately 10-20 nm apart) and oriented with the same polarity.


negative regulation of cilium movement

description: Any process that decreases the rate, frequency, or extent of cilium movement, the directed, self-propelled movement of a cilium.


description: Catalysis of the reaction: acetyl-CoA + S(2-) = CoA + thioacetate.


sorbose biosynthetic process

description: The chemical reactions and pathways resulting in the formation of sorbose, the ketohexose xylo-2-hexulose. Sorbose is produced commercially by fermentation and is used as an intermediate in the manufacture of ascorbic acid.


name: positive regulation of extrinsic apoptotic signaling pathway in absence of ligand

description: Any process that activates or increases the frequency, rate or extent of extrinsic apoptotic signaling pathway in absence of ligand.


tRNA(Ile)-lysidine synthase activity

description: Catalysis of the ligation of lysine onto the cytidine residue present at the wobble position (usually position 34) of an AUA-specific isoleucine tRNA, to form the derivative lysidine. This modification converts both the codon specificity of tRNA(Ile) from AUG to AUA and its amino acid specificity from methionine to isoleucine.


name: transcription ternary complex disassembly

description: The disaggregation of a transcription ternary complex, composed of RNA polymerase, template DNA, and an RNA transcript, into its constituent components.


follicle cell microvillus organization

description: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a microvillus on a follicle cell. A microvillus is a thin cylindrical membrane-covered projection on the surface of an animal cell containing a core bundle of actin filaments.


name: macrophage colony-stimulating factor receptor activity

description: Combining with macrophage colony-stimulating factor (M-CSF) receptor ligand and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP + a protein-L-tyrosine = ADP + a protein-L-tyrosine phosphate.


name: Mo(VI)-molybdopterin cytosine dinucleotide metabolic process

description: The chemical reactions and pathways involving Mo(VI)-molybdopterin cytosine dinucleotide.


regulation of stomatal closure

description: Any process that modulates the rate, frequency, or extent of stomatal closure. Stomatal closure is the process of closing of stomata, pores in the epidermis of leaves and stems bordered by two guard cells and serving in gas exchange.


name: homospermidine synthase (spermidine-specific) activity

description: Catalysis of the reaction: spermidine + putrescine = sym-homospermidine + propane-1,3-diamine.


3-deoxyoctulosonase activity

description: Catalysis of the reaction: 3-deoxyoctulosonyl-lipopolysaccharide + H2O = 3-deoxyoctulosonic acid + lipopolysaccharide.


description: Catalysis of the reactions: a (3Z)-enoyl-CoA = a 4-saturated (2E)-enoyl-CoA or a (3E)-enoyl-CoA = a 4-saturated (2E)-enoyl-CoA.


description: Catalysis of the transfer of a beta-D-glucosyl residue from UDP-glucose to a glucosylhydroxymethylcytosine residue in DNA.


interleukin-6 receptor activity

description: Combining with interleukin-6 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


description: Catalysis of the cyclization of part of a 1,4-alpha-D-glucan chain by formation of a 1,4-alpha-D-glucosidic bond.


name: negative regulation of maltotriulose transport

description: Any process that stops, prevents or reduces the frequency, rate or extent of maltotriulose transport.


name: negative regulation of water channel activity

description: Any process that stops, prevents or reduces the frequency, rate or extent of water channel activity.


description: Catalysis of the reaction: GDP-L-fucose + beta-D-galactosyl-(1,3)-N-acetyl-D-glucosaminyl-R = GDP + beta-D-galactosyl-(1,3)-[alpha-L-fucosyl-(1,4)]-N-acetyl-D-glucosaminyl-R.


description: Catalysis of the reaction: succinyl-CoA + lysine in peptide = CoA + N-succinyl-lysine-peptide.


name: clathrin coat assembly involved in endocytosis

description: The process that results in the assembly of clathrin triskelia into a clathrin cage during endocytosis. Clathrin is recruited to the plasma membrane via interaction with scaffolding proteins that bridge between clathtin and cell surface receptors. Clathrin coat formation is concomittant with coated pit formation leading to endocytic vesicle formation.


name: CD8-positive, alpha-beta T cell activation

description: The change in morphology and behavior of a CD8-positive, alpha-beta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.


cochlear nucleus development

description: The process whose specific outcome is the progression of the cochlear nucleus over time, from its formation to the mature structure.


name: positive regulation of receptor recycling

description: Any process that activates or increases the frequency, rate or extent of receptor recycling.


name: bilirubin transmembrane transporter activity

description: Enables the transfer of bilirubin from one side of a membrane to the other. Bilirubin is a linear tetrapyrrole produced in the reticuloendothelial system from biliverdin and transported to the liver as a complex with serum albumin. In the liver, bilirubin is converted to bilirubin bisglucuronide, which is excreted in the bile.


name: positive regulation of homotypic cell-cell adhesion

description: Any process that activates or increases the frequency, rate, or extent of homotypic cell-cell adhesion.


name: GPI anchor biosynthetic process via N-threonyl-glycosylphosphatidylinositolethanolamine

description: The chemical reactions and pathways resulting in the formation of a C-terminal peptidyl-threonyl ethanolamide-linked glycosylphosphatidylinositol (GPI) anchor following hydrolysis of a threonyl-peptide bond in the carboxy-terminal region of a membrane-associated protein.


description: Catalysis of the reaction: 4-hydroxybenzoic acid + L-glutamate + ATP = H+ + N-(4-hydroxybenzoyl)-L-glutamate + AMP + diphosphoric acid.


name: nicotinate transmembrane transporter activity

description: Enables the transfer of nicotinate from one side of a membrane to the other.


plasma lipoprotein particle disassembly

description: The disaggregation of a plasma lipoprotein particle into its constituent components.


'de novo' XMP biosynthetic process

description: The chemical reactions and pathways resulting in the formation of XMP, xanthosine monophosphate, from simpler precursors.


name: negative regulation of CD8-positive, alpha-beta T cell differentiation

description: Any process that stops, prevents, or reduces the rate of CD8-positive, alpha-beta T cell differentiation.


lactose binding

description: Binding to lactose, a disaccharide of glucose and galactose, the carbohydrate of milk.


name: regulation of mitochondrial RNA catabolic process

description: Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving catabolism in the mitochondrion of RNA transcribed from the mitochondrial genome.


one-carbon metabolic process

description: The chemical reactions and pathways involving the transfer of one-carbon units in various oxidation states.


description: Catalysis of the reaction: (3R)-hydroxypalmitoyl-[acyl-carrier protein] = 2-hexadecenoyl-[acyl-carrier protein] + H2O.


name: catechol-containing compound catabolic process

description: The chemical reactions and pathways resulting in the breakdown of catechol-containing compounds. Catechol is a compound containing a pyrocatechol nucleus or substituent.


description: Catalysis of the reaction: glucosyl-N-acetylglucosamine + H2O = glucosamine + N-acetylglucosamine.


name: ACP-dependent peptidyl-lysine N6-palmitoyltransferase activity

description: Catalysis of the reaction: hexadecanoyl-[ACP] + L-lysyl-[protein] = H+ + holo-[ACP] + N(6)-hexadecanoyl-L-lysyl-[protein].


name: cellular response to glucocorticoid stimulus

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucocorticoid stimulus. Glucocorticoids are hormonal C21 corticosteroids synthesized from cholesterol with the ability to bind with the cortisol receptor and trigger similar effects. Glucocorticoids act primarily on carbohydrate and protein metabolism, and have anti-inflammatory effects.


name: phosphogluconate dehydrogenase (decarboxylating) activity

description: Catalysis of the reaction: 6-phospho-D-gluconate + NADP+ = D-ribulose 5-phosphate + CO2 + NADPH + H+.


mature B cell differentiation

description: The process in which transitional stage B cells acquire the specialized features of mature B cells in the spleen.


name: L-iditol 2-dehydrogenase (NAD+) activity

description: Catalysis of the reaction: L-iditol + NAD+ = L-sorbose + NADH + H+. Acts on a number of sugar alcohols, including (but not limited to) L-iditol, D-glucitol, D-xylitol, and D-galactitol.


mammary gland development

description: The process whose specific outcome is the progression of the mammary gland over time, from its formation to the mature structure. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk. Its development starts with the formation of the mammary line and ends as the mature gland cycles between nursing and weaning stages.


name: negative regulation of Rho protein signal transduction

description: Any process that stops, prevents, or reduces the frequency, rate or extent of Rho protein signal transduction.


description: Catalysis of the reaction: guanosine(26)/guanosine(27) in tRNA + 4 S-adenosyl-L-methionine = 4 H+ + N(2)-dimethylguanosine(26)/N(2)-dimethylguanosine(27) in tRNA + 4 S-adenosyl-L-homocysteine.


description: Catalysis of the reaction: acyl-[acyl-carrier protein] + malonyl-[acyl-carrier protein] = 3-oxoacyl-[acyl-carrier protein] + CO2 + [acyl-carrier protein].


dUMP biosynthetic process

description: The chemical reactions and pathways resulting in the formation of dUMP, deoxyuridine monophosphate (2'-deoxyuridine 5'-phosphate).


T cell lineage commitment

description: The process in which a lymphoid progenitor cell becomes committed to becoming any type of T cell.


filtration diaphragm assembly

description: The aggregation, arrangement and bonding together of a set of components to form a filtration diaphragm, a specialized cell-cell junction found between the cells of the excretory system, which provides a barrier for filtration of blood or hemolymph.


name: purine-specific mismatch base pair DNA N-glycosylase activity

description: Catalysis of the removal of purines present in mismatches, especially opposite oxidized purines, by cleaving the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apurinic (AP) site.


name: modulation by symbiont of host ethylene-mediated defense response

description: Any process in which a symbiont modulates the frequency, rate or extent of the ethylene-mediated defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.


name: positive regulation of execution phase of apoptosis

description: Any process that activates or increases the frequency, rate or extent of execution phase of apoptosis.


name: regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway

description: Any process that modulates the frequency, rate or extent of a hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway.


trigeminal ganglion formation

description: The process that gives rise to the trigeminal ganglion. This process pertains to the initial formation of a structure from unspecified parts.


cardiac muscle cell proliferation

description: The expansion of a cardiac muscle cell population by cell division.


name: dihydropyrimidine dehydrogenase (NADP+) activity

description: Catalysis of the reaction: 5,6-dihydrouracil + NADP+ = uracil + NADPH + H+.


Wnt receptor catabolic process

description: The chemical reactions and pathways resulting in the breakdown of a Wnt receptor. Internalized Wnt receptors can be recycled to the plasma membrane or sorted to lysosomes for protein degradation.


description: Catalysis of the reaction: S-adenosyl-L-methionine(1+) = 1-aminocyclopropane-1-carboxylate + S-methyl-5'-thioadenosine + H+.


name: negative regulation of endodermal cell differentiation

description: Any process that stops, prevents or reduces the frequency, rate or extent of endodermal cell differentiation.


L-threonate 3-dehydrogenase activity

description: Catalysis of the reaction: L-threonate + NAD+ = 3-dehydro-L-threonate + H+ + NADH.


syn-pimara-7,15-diene synthase activity

description: Catalysis of the reaction: 9-alpha-copalyl diphosphate = 9-beta-pimara-7,15-diene + diphosphate.


dihydrofolate reductase activity

description: Catalysis of the reaction: 5,6,7,8-tetrahydrofolate + NADP+ = 7,8-dihydrofolate + NADPH + H+.


name: calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules

description: The attachment of one cell to another cell via adhesion molecules that do not require the presence of calcium for the interaction.


description: Catalysis of the reaction: 3,4-dichlorobenzoate + O2 + a reduced electron acceptor = 3,4-dichlorobenzoate-cis-4,5-diol + an oxidized electron acceptor.


central nervous system vasculogenesis

description: The differentiation of endothelial cells from progenitor cells during blood vessel development, and the de novo formation of blood vessels and tubes in the central nervous system. The capillary endothelial cells in the brain are specialized to form the blood-brain barrier.


name: B cell tolerance induction in mucosal-associated lymphoid tissue

description: Tolerance induction taking place in the mucosal-associated lymphoid tissue (MALT) mediated by B cells.


name: mitochondrial fragmentation involved in apoptotic process

description: The change in the morphology of the mitochondria in an apoptotic cell from a highly branched network to a fragmented vesicular form.


name: positive regulation of activin receptor signaling pathway

description: Any process that activates or increases the frequency, rate or extent of the activity of any activin receptor signaling pathway.


name: regulation of toll-like receptor 6 signaling pathway

description: Any process that modulates the frequency, rate, or extent of toll-like receptor 6 signaling pathway.


endocardial cell differentiation

description: The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of an endocardial cell. An endocardial cell is a specialized endothelial cell that makes up the endocardium portion of the heart. The endocardium is the innermost layer of tissue of the heart, and lines the heart chambers.


regulation of proton transport

description: Any process that modulates the frequency, rate or extent of proton transport into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


response to methylglyoxal

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylglyoxal stimulus. Methylglyoxal is a 2-oxoaldehyde derived from propanal.


name: regulation of smooth muscle contraction involved in micturition

description: Any process that modulates the frequency, rate or extent of smooth muscle contraction involved in micturition.


name: oxidoreductase activity, acting on hydrogen as donor

description: Catalysis of an oxidation-reduction (redox) reaction in which hydrogen acts as an electron donor.


tyrosine biosynthetic process

description: The chemical reactions and pathways resulting in the formation of tyrosine, an aromatic amino acid, 2-amino-3-(4-hydroxyphenyl)propanoic acid.


name: receptor guanylyl cyclase signaling pathway

description: The series of molecular signals initiated by an extracellular ligand binding to a receptor on the surface of the target cell where the receptor possesses guanylyl cyclase activity, and ending with the regulation of a downstream cellular process, e.g. transcription.


Golgi inheritance

description: The partitioning of Golgi apparatus between daughter cells at cell division.


name: cellular response to thyroid hormone stimulus

description: A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thyroid hormone stimulus.


name: chemokine (C-C motif) ligand 11 production

description: The appearance of chemokine (C-C motif) ligand 11 (CCL11, also known as eotaxin-1) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


name: regulation of mesodermal cell differentiation

description: Any process that modulates the frequency, rate or extent of mesodermal cell differentiation.


name: negative regulation of amoeboid sperm motility

description: Any process that stops, prevents or reduces the frequency, rate or extent of amoeboid sperm motility.


name: mast cell secretagogue receptor activity

description: Combining with basic secretagogues to initiate pseudo-allergic reactions in mast cells.


name: regulation of pheromone response MAPK cascade

description: Any process that modulates the frequency, rate or extent of a pheromone response MAPK cascade.


peptidyl-lysine modification

description: The modification of peptidyl-lysine.


name: protein-N(PI)-phosphohistidine-N,N'-diacetylchitobiose phosphotransferase system transporter activity

description: Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + N,N'-diacetylchitobiose(out) = protein histidine + N,N'-diacetylchitobiose phosphate(in).


hyaluranon cable assembly

description: A process that results in the aggregation, arrangement and bonding together of a hyaluranon cable, a cable structure, surrounding some cell types (e.g. proximal or bronchial tubular epithelial cells), and composed of hyaluranon (HA), a ubiquitous connective tissue glycosaminoglycan.


11-oxo-beta-amyrin catabolic process

description: The chemical reactions and pathways resulting in the breakdown of 11-oxo-beta-amyrin.


primitive hemopoiesis

description: A first transient wave of blood cell production that, in vertebrates, gives rise to erythrocytes (red blood cells) and myeloid cells.


ribonucleotide binding

description: Binding to a ribonucleotide, any compound consisting of a ribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety.


description: Catalysis of the reaction: UDP-galactose + O-beta-D-xylosylprotein = UDP + 4-beta-D-galactosyl-O-beta-D-xylosylprotein.


description: Catalysis of the reaction: tRNA-(2-methylthio-N-6-isopentenyl adenosine) = tRNA-(2-methylthio-N-6-(cis-hydroxy)isopentenyl adenosine) + O2. 2-methylthio-N-6-isopentenyl adenosine is also known as ms2i6A; 2-methylthio-N-6-(cis-hydroxy)isopentenyl adenosine is also known as ms2io6A and 2-methylthio-cis-ribozeatin.


name: coenzyme F420-dependent 2,4,6-trinitrophenol hydride reductase activity

description: Catalysis of the reaction: trinitrophenol hydride Meisenheimer complex + H- = trinitrophenol dihydride Meisenheimer complex (aci form). Coenzyme F420 supplies the hydride (H-) in the reaction.


regulation of ferroptosis

description: Any process that modulates the frequency, rate or extent of ferroptosis.


name: negative regulation of metanephric comma-shaped body morphogenesis

description: Any process that stops, prevents, or reduces the frequency, rate or extent of metanephric comma-shaped body morphogenesis.


name: establishment or maintenance of cytoskeleton polarity involved in gastrulation

description: Any cellular process that results in the specification, formation or maintenance of polarized cytoskeletal structures that contribute to the cell polarity of a migrating ameboid cell taking part in gastrulation.


lipoprotein localization

description: Any process in which a lipoprotein is transported to, or maintained in, a specific location.


name: pyrimidine dimer DNA N-glycosylase activity

description: Catalysis of the removal of pyrimidine dimers by removing the 5' pyrimidine of the dimer by cleaving the N-C1' glycosidic bond between the 5' pyrimidine of the dimer and the deoxyribose sugar. The reaction releases the 5' pyrimidine of the dimer and leaves an apurinic (AP) site. The reaction involves the formation of a covalent enzyme substrate intermediate. Release of the enzyme and free base by a beta-elimination or a beta, gamma-elimination mechanism results in the cleavage of the DNA backbone 3' of the apyrimidinic (AP) site.


description: Catalysis of the reaction: 3-chloro-L-alanine + thioglycolate = S-carboxymethyl-L-cysteine + chloride + H+.


2'-deoxyadenosine deaminase activity

description: Catalysis of the reaction: 2'-deoxyadenosine + H2O = deoxyinosine + NH3.


D-valine catabolic process

description: The chemical reactions and pathways resulting in the breakdown of D-valine.


name: secondary active organic cation transmembrane transporter activity

description: Enables the transfer of organic cations from one side of a membrane to the other, up the solute's concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction.


name: neutral L-amino acid:sodium symporter activity

description: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: neutral L-amino acid(out) + Na+(out) = neutral L-amino acid(in) + Na+(in).


name: antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent

description: The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class I protein complex following intracellular transport via a TAP-independent ER pathway. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell and becomes associated with the MHC class I molecule in the ER following transport from the cytosol via a TAP-independent pathway. Class I here refers to classical class I molecules.


name: adenylate cyclase-inhibiting opioid receptor signaling pathway

description: An adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway initiated by an opioid binding to its receptor, and ending with the regulation of a downstream cellular process.


regulation of vasoconstriction

description: Any process that modulates the frequency, rate or extent of reductions in the diameter of blood vessels.


name: positive regulation of glomerular mesangial cell proliferation

description: Any process that increases the frequency, rate or extent of glomerular mesangial cell proliferation.


description: Catalysis of the reaction: carboxymethoxysuccinate = fumarate + glycolate.


dihydrosphingosine-1-P pathway

description: A phosphatidylethanolamine biosynthetic process that proceeds via the enzymatic action of dihydrosphingosine phosphate lyase.


coronary vasculature morphogenesis

description: The process in which the anatomical structures of blood vessels of the heart are generated and organized. The blood vessel is the vasculature carrying blood.


development of symbiont in host

description: The progression of an organism from an initial condition to a later condition, occurring within the cells or tissues of the host organism. This may (but not necessarily) include a filamentous growth form, and also can include secretion of proteases and lipases to break down host tissue. The host is defined as the larger of the organisms involved in a symbiotic interaction.


amyloid-beta metabolic process

description: The chemical reactions and pathways involving amyloid-beta, a glycoprotein associated with Alzheimer's disease, and its precursor, amyloid precursor protein (APP).


name: response to oscillatory fluid shear stress

description: Any response to fluid shear stress where the fluid is moving across a solid surface with an oscillatory flow. Disturbed flow patterns at the arterial bifurcations and curvatures may cause endothelial dysfunction, which initiates atherosclerosis.


hydroxyglutamate decarboxylase activity

description: Catalysis of the reaction: 3-hydroxy-L-glutamate + H+ = 4-amino-3-hydroxybutanoate + CO2.


name: negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

description: Any process that stops, prevents or reduces the frequency, rate or extent of extrinsic apoptotic signaling pathway via death domain receptors.


name: regulation of endocardial cushion cell differentiation

description: Any process that modulates the frequency, rate or extent of cell differentiation, the process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of an endocardial cushion cell.


activation of recombination (HML)

description: The activation of recombination at a mating type locus, such that it is used in preference to the other donor locus for mating type switching; exemplified by the HML locus and surrounding sequences on Chromosome III in Saccharomyces cerevisiae.


serine-glyoxylate transaminase activity

description: Catalysis of the reaction: L-serine + glyoxylate = 3-hydroxypyruvate + glycine.


description: Catalysis of the endolytic cleavage of beta-1,4-galactosaminic bonds between N-acetylgalactosamine and either D-glucuronic acid or L-iduronic acid to produce a mixture of Delta4-unsaturated oligosaccharides of different sizes that are ultimately degraded to Delta4-unsaturated tetra- and disaccharides.


description: Catalysis of the reaction: S-adenosyl-L-methionine + cycloartenol = (24R)-24-methylcycloart-25-en-3beta-ol + S-adenosyl-L-homocysteine + H+.


name: regulation of transport across blood-brain barrier

description: Any process that modulates the frequency, rate or extent of transport across the blood-brain barrier.


temperature homeostasis

description: A homeostatic process in which an organism modulates its internal body temperature.


description: Catalysis of the reaction: N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenol + UDP-N-acetyl-D-glucosamine = N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenyl-N-acetylglucosamine + UDP.


tryptophan 2-monooxygenase activity

description: Catalysis of the reaction: L-tryptophan + O2 = CO2 + H2O + indole-3-acetamide.


name: regulation of collagen metabolic process

description: Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the metabolism of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals.


name: nucleotide-excision repair, DNA damage removal

description: The removal of the oligonucleotide that contains the DNA damage. The oligonucleotide is formed by dual incisions that flank the site of DNA damage.


erythrocyte aggregation

description: The adhesion of one erythrocyte to one or more other erythrocytes via adhesion molecules.


description: The process in which one relatively unspecialized immature cystocyte of the germ-line cyst in the germarium acquires the specialized features of an oocyte. An example of this process can be found in Drosophila melanogaster.


description: Catalysis of the reaction: 1-O-caffeoyl-beta-D-glucose + S-adenosyl-L-methionine = 1-O-feruloyl-beta-D-glucose + S-adenosyl-L-homocysteine + H+.


presynapse organization

description: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a presynapse.


S-methyl-5-thioribose kinase activity

description: Catalysis of the reaction: S-methyl-5-thio-D-ribose + ATP = S-methyl-5-thio-alpha-D-ribose 1-phosphate + ADP + 2 H+.


phytochelatin-metal complex formation

description: A phytochelatin metabolic process in which a metal is incorporated with phytochelatin to form a complex.


[4Fe-4S] cluster assembly

description: The incorporation of four iron atoms and four sulfur atoms into an iron-sulfur cluster.


description: Catalysis of the transfer of a galactose residue from a donor molecule, such as GDP-galactose or UDP-galactose, to an oligosaccharide, forming an alpha-(1->3) linkage.


name: tyrosine-based site-specific recombinase activity

description: Catalysis of the formation of new phosphodiester bonds between a pair of short, unique DNA target sequences; occurs through a phosphotyrosyl intermediate in which the target sequence is first cleaved by the nucleophilic attack by a tyrosine in the active site.


name: intracellularly calcium-gated channel activity

description: Enables the transmembrane transfer of a solute by a channel that opens when calcium ions bind on the intracellular side of the channel complex or one of its constituent parts.


dTTP metabolic process

description: The chemical reactions and pathways involving dTTP, deoxyribosylthymine triphosphate.


diphthine synthase activity

description: Catalysis of the reaction: 2-[(3S)-amino-3-carboxypropyl]-L-histidyl-[translation elongation factor 2] + 3 S-adenosyl-L-methionine = diphthine-[translation elongation factor 2] + 3 H+ + 3 S-adenosyl-L-homocysteine.


2,5-dioxopiperazine hydrolase activity

description: Catalysis of the reaction: 2,5-dioxopiperazine + H2O = glycylglycine.


name: 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity

description: Catalysis of the removal of 8-oxo-7,8-dihydroguanine bases by cleaving the N-C1' glycosidic bond between the oxidized purine and the deoxyribose sugar.


cysteine lyase activity

description: Catalysis of the reaction: L-cysteine + sulfite = L-cysteate + sulfide.


description: Catalysis of the reaction: (2Z)-2-(acetamidomethylene)-3-(hydroxymethyl)succinate + 2 H2O + H+ = 2-(hydroxymethyl)-4-oxobutanoate + acetate + CO2 + NH4.


name: low-affinity phosphate transmembrane transporter activity

description: Enables the transfer of phosphate from one side of a membrane to the other. In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations.


N-glycan processing to lysosome

description: The modification of high-mannose N-glycans by UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase and the subsequent removal of the N-acetylglucosamine residues yielding mannose-6-P that occurs in the ER-Golgi apparatus to N-glycans destined for the lysosome.


malate dehydrogenase (NADP+) activity

description: Catalysis of the reaction: (S)-malate + NADP+ = oxaloacetate + NADPH + H+.


floral organ abscission

description: The controlled shedding of floral organs.


enucleation

description: The process in which nucleated precursor cells lose their nucleus.


description: Catalysis of the reaction: (6E)-8-hydroxygeraniol + NADP = (6E)-8-hydroxygeranial + NADPH + H+.


snRNA transcription

description: The synthesis of small nuclear RNA (snRNA) from a DNA template.


methionyl-tRNA aminoacylation

description: The process of coupling methionine to methionyl-tRNA, catalyzed by methionyl-tRNA synthetase. The methionyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2'-OH group of a methionine-accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification.


B-1a B cell differentiation

description: The process in which B cells acquire the specialized features of B-1a B cells. B-1a B cells are B-1 cells that express CD5 and arise from fetal liver precursors.


positive stranded viral RNA replication

description: A viral genome replication process where the template genome is positive stranded, single stranded RNA ((+)ssRNA). Replication of the positive strand leads to dsRNA formation, which in turn is transcribed into positive single stranded RNA.


auditory receptor cell morphogenesis

description: Any process that alters the size or shape of an auditory receptor cell.


hypothalamus development

description: The progression of the hypothalamus region of the forebrain, from its initial formation to its mature state.


chrysobactin biosynthetic process

description: The chemical reactions and pathways resulting in the formation of the siderophore chrysobactin (alpha-N-(2,3-dihydroxybenzoyl)-D-lysyl-L-serine).


description: Catalysis of the reaction: 4-hydroxy-L-glutamate + 2-oxoglutarate = 4-hydroxy-2-oxoglutarate + L-glutamate.


description: Catalysis of the reaction: 2-methylpropanoate + ATP = 2-methylpropanoyl phosphate + ADP + H+.


description: Catalysis of the transfer of a linoleoyl ((9Z,12Z)-octadeca-9,12-dienoyl) group from phosphatidylcholine to an oxygen atom on a cardiolipin molecule.


cellular response to curcumin

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a curcumin stimulus.


amylin receptor 3 signaling pathway

description: The series of molecular signals initiated by an extracellular amylin, or another ligand, combining with an amylin receptor 3 (AMY3), a G protein-coupled receptor complex, on the surface of the target cell. The AMY3 signaling pathway can also be initiated by the amyloid-beta complex. AMY3 signaling results in increased import of calcium ions into the cytosol across plasma membrane, increased phosphorylation of ERK1/2, Act, and a PKA regulatory subunit II, as well as increased expression of cFos.


name: epithelial cell proliferation involved in salivary gland morphogenesis

description: The multiplication or reproduction of epithelial cells of the submandibular salivary gland, resulting in the expansion of a cell population and the shaping of the gland.


isopimaradienol hydroxylase activity

description: Catalysis of the reaction: H+ + isopimaradienol + NADPH + O2 = isopimaradiene-diol + NADP + H2O.


tartrate catabolic process

description: The chemical reactions and pathways resulting in the breakdown of tartrate.


name: regulation of hepatocyte growth factor receptor signaling pathway

description: Any process that modulates the frequency, rate or extent of hepatocyte growth factor receptor signaling pathway.


primary alcohol metabolic process

description: The chemical reactions and pathways involving primary alcohols. A primary alcohol is any alcohol in which a hydroxy group, -OH, is attached to a saturated carbon atom which has either three hydrogen atoms attached to it or only one other carbon atom and two hydrogen atoms attached to it.


paraxial mesoderm development

description: The process whose specific outcome is the progression of the paraxial mesoderm over time, from its formation to the mature structure. The paraxial mesoderm is the mesoderm located bilaterally adjacent to the notochord and neural tube.


name: induction of platelet aggregation in another organism

description: Any process in which an organism activates, maintains or increases the frequency, rate or extent of platelet aggregation in another organism.


description: Catalysis of the reaction: GDP-L-fucose + beta-D-galactosyl-R = GDP + alpha-L-fucosyl-(1,2)-beta-D-galactosyl-R.


cell wall biogenesis

description: A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cell wall. Includes biosynthesis of constituent macromolecules, such as proteins and polysaccharides, and those macromolecular modifications that are involved in synthesis or assembly of the cellular component. A cell wall is the rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis.


name: aldarate transmembrane transporter activity

description: Enables the transfer of aldarate from one side of a membrane to the other.


protein kinase C deactivation

description: Any process resulting in the inhibition or termination of the activity of protein kinase C.


name: acetyl-coenzyme A:acetyl alcohol acetyltransferase activity

description: Catalysis of the reaction: benzyl alcohol + acetyl-CoA = benzyl acetate + coenzyme A.


description: Catalysis of the reaction: N-acetyl-D-glucosaminyldiphosphoundecaprenol + UDP-D-glucose = beta-D-glucosyl-1,4-N-acetyl-D-glucosaminyldiphosphoundecaprenol + UDP.


homogentisate 1,2-dioxygenase activity

description: Catalysis of the reaction: homogentisate + O2 = 4-maleylacetoacetate + H+.


name: negative regulation of mast cell activation

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of mast cell activation.


name: leukocyte adhesion to vascular endothelial cell

description: The attachment of a leukocyte to vascular endothelial cell via adhesion molecules.


name: poly(glycerol phosphate) teichoic acid metabolic process

description: The chemical reactions and pathways involving poly(glycerol phosphate) teichoic acid.


intussusceptive angiogenesis

description: The formation of new blood vessels as a result of the insertion and extension of lumenal tissue pillars.


dITP catabolic process

description: The chemical reactions and pathways resulting in the breakdown of dITP, a deoxyinosine phosphate compound having a triphosphate group at the 5'-position.


phosphocreatine catabolic process

description: The chemical reactions and pathways resulting in the breakdown of phosphocreatine, a phosphagen of creatine which is synthesized and broken down by creatine phosphokinase.


sorocarp stalk morphogenesis

description: The process in which the sorocarp stalk is generated and organized. The sorocarp stalk is a tubular structure that consists of cellulose-covered cells stacked on top of each other and surrounded by an acellular stalk tube composed of cellulose and glycoprotein. An example of this process is found in Dictyostelium discoideum.


sperm mitochondrial sheath assembly

description: The assembly and organization of the sperm mitochondrial sheath, the tightly packed helical sheath of ATP-producing mitochondria restricted to the midpiece of the sperm flagellum.


name: positive regulation of vascular wound healing

description: Any process that increases the rate, frequency, or extent of blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels and contribute to the series of events that restore integrity to damaged vasculature.


RNA localization to chromatin

description: A process in which RNA is transported to and maintained in a part of a chromosome that is organized into chromatin.


levanase activity

description: Catalysis of the random hydrolysis of 2,6-beta-D-fructofuranosidic linkages in 2,6-beta-D-fructans (levans) containing more than 3 fructose units.


ionotropic taste receptor activity

description: Enables the transmembrane transfer of an ion by a channel that opens when a soluble compound has been bound by the channel complex or one of its constituent parts.


name: mating-type factor pheromone receptor activity

description: Combining with a mating-type factor pheromone to initiate a change in cell activity.


name: mesonephric interstitial fibroblast development

description: The process whose specific outcome is the progression of a mesonephric interstitial fibroblast over time, from its formation to the mature structure.


methanol metabolic process

description: The chemical reactions and pathways involving methanol, CH3-OH, a colorless, flammable, mobile, poisonous liquid, widely used as a solvent.


name: 4-methoxybenzoate monooxygenase (O-demethylating) activity

description: Catalysis of the reaction: 4-methoxybenzoate + AH(2) + O2 = 4-hydroxybenzoate + A + formaldehyde + H2O.


name: regulation of lipoprotein particle clearance

description: Any process that modulates the rate, frequency, or extent of lipoprotein particle clearance. Lipoprotein particle clearance is the process in which a lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.


name: positive regulation of endothelial cell migration

description: Any process that increases the rate, frequency, or extent of the orderly movement of an endothelial cell into the extracellular matrix to form an endothelium.


ureter development

description: The process whose specific outcome is the progression of the ureter over time, from its formation to the mature structure. The ureter is a muscular tube that transports urine from the kidney to the urinary bladder or from the Malpighian tubule to the hindgut.


name: tRNA-derived regulatory ncRNA processing

description: A process leading to the generation of a functional small regulatory non-coding RNA derived from a tRNA.


protein localization to Cajal body

description: A process in which a protein is transported to, or maintained in, a location within a Cajal body.


membrane raft distribution

description: The process that establishes the spatial arrangement of membrane rafts within a cellular membrane.


name: negative regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching

description: Any process that stops, prevents or reduces the frequency, rate or extent of vascular smooth muscle cell differentiation involved in phenotypic switching.


name: positive regulation of endocytic recycling

description: Any process that activates or increases the frequency, rate or extent of endocytic recycling.


nucleoside ribosyltransferase activity

description: Catalysis of the reaction: D-ribosyl-base1 + base2 = D-ribosyl-base2 + base1.


name: regulation of cargo loading into COPII-coated vesicle

description: Any process that modulates the frequency, rate or extent of cargo loading into COPII-coated vesicle.


description: Catalysis of the reaction: ADP-D-glycero-D-manno-heptose = ADP-L-glycero-D-manno-heptose.


arabinogalactan binding

description: Binding to arabinogalactan.


name: response to mitotic DNA integrity checkpoint signaling

description: A process that occurs in response to signals generated as a result of mitotic DNA integrity checkpoint signaling.


amylin receptor signaling pathway

description: A G protein-coupled receptor signaling pathway initiated by amylin binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process.


mycolic acid metabolic process

description: The chemical reactions and pathways involving mycolic acids, beta-hydroxy fatty acids with a long alpha-alkyl side chain.


name: regulation of toll-like receptor signaling pathway

description: Any process that modulates the frequency, rate, or extent of toll-like receptor signaling pathway.


maintenance of Golgi location

description: Any process in which the Golgi is maintained in a specific location within a cell and prevented from moving elsewhere.


name: globoside biosynthetic process via lactosylceramide

description: The chemical reactions and pathways resulting in the formation of globosides that begins with the formation of lactosylceramides, Gal-beta-(1->4)-Glc-beta-(1->1') ceramides, any compound formed by the replacement of the glycosidic C1 hydroxyl group of lactose by a ceramide group.


berbamunine metabolic process

description: The chemical reactions and pathways involving berbamunine, an isoquinoline alkaloid.


name: planar cell polarity pathway involved in cardiac right atrium morphogenesis

description: The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity that contributes to the shaping of the cardiac right atrium.


name: presynaptic modulation of chemical synaptic transmission

description: Any process, acting in the presynapse that results in modulation of chemical synaptic transmission.


RNA-DNA hybrid ribonuclease activity

description: Catalysis of the endonucleolytic cleavage of RNA in RNA-DNA hybrids to 5'-phosphomonoesters.


pole cell fate determination

description: The cell fate determination process in which a cell becomes capable of differentiating autonomously into a pole cell regardless of its environment; upon determination, the cell fate cannot be reversed.


name: detection of stimulus involved in sensory perception of pain

description: The series of events involved in the perception of pain in which a stimulus is received and converted into a molecular signal.


N-acetylgalactosamine kinase activity

description: Catalysis of the reaction: ATP + N-acetyl-D-galactosamine = ADP + N-acetyl-alpha-D-galactosamine 1-phosphate.


facial nerve development

description: The process whose specific outcome is the progression of the facial nerve over time, from its formation to the mature structure. This sensory and motor nerve supplies the muscles of facial expression and the expression and taste at the anterior two-thirds of the tongue. The principal branches are the superficial ophthalmic, buccal, palatine and hyomandibular. The main trunk synapses within pterygopalatine ganglion in the parotid gland and this ganglion then gives off nerve branches which supply the lacrimal gland and the mucous secreting glands of the nasal and oral cavities.


methylamine metabolic process

description: The chemical reactions and pathways involving methylamine (CH3NH2).


name: detection of humidity stimulus involved in sensory perception

description: The series of events in which a humidity stimulus is received and converted into a molecular signal as part of the sensory perception of humidity.


septation initiation signaling

description: The series of molecular signals, mediated by the small GTPase Ras, that results in the initiation of contraction of the contractile ring, at the beginning of cytokinesis and cell division by septum formation. The pathway coordinates chromosome segregation with mitotic exit and cytokinesis.


glossopharyngeal nerve maturation

description: A developmental process, independent of morphogenetic (shape) change, that is required for the glossopharyngeal nerve to attain its fully functional state. Various sensory and motor branches of the glossopharyngeal nerve supply nerve connections to the pharynx and back of the tongue. The branchial motor component contains motor fibers that innervate muscles that elevate the pharynx and larynx, and the tympanic branch supplies parasympathetic fibers to the otic ganglion.


name: cell proliferation involved in imaginal disc-derived wing morphogenesis

description: The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to imaginal disc-derived wing morphogenesis.


name: dorsal/ventral pattern formation, imaginal disc

description: The establishment, maintenance and elaboration of the dorsal/ventral axis of the imaginal disc. Imaginal disks are masses of hypodermic cells, carried by the larvae of some insects after leaving the egg, from which masses the wings and legs of the adult are subsequently formed.


name: proximal convoluted tubule segment 1 cell fate commitment

description: The process in which the developmental fate of a cell becomes restricted such that it will develop into an S1 cell in the kidney.


description: Catalysis of the reaction: beta-D-glucosaminyl-(1->4)-N-acetyl-D-glucosamine + H2O = D-glucosamine + N-acetyl-D-glucosamine.


morphine metabolic process

description: The chemical reactions and pathways involving morphine, 17-methyl-7,8-didehydro-4,5alpha-epoxymorphinan-3,6alpha-diol. Morphine is a highly potent opiate analgesic psychoactive drug obtained form the opium poppy, Papaver somniferum.


ent-cassadiene-C2-hydroxylase activity

description: Catalysis of the reaction: ent-cassa-12,15-diene + NADPH + O2 + H+ = 2alpha-hydroxy-ent-cassadiene + NADP + H2O.


description: Catalysis of the reaction: (1R,9R,10S,11R,12R,19R)-12-ethyl-10,11-dihydroxy-5-methoxy-10-(methoxycarbonyl)-8-methyl-8,16-diazapentacyclo[10.6.1.0^{1,9}.0^{2,7}.0^{16,19}]nonadeca-2(7),3,5,13-tetraen-16-ium + acetyl-CoA = (1R,9R,10S,11R,12R,19R)-11-(acetyloxy)-12-ethyl-10-hydroxy-5-methoxy-10-(methoxycarbonyl)-8-methyl-8,16-diazapentacyclo[10.6.1.0^{1,9}.0^{2,7}.0^{16,19}]nonadeca-2(7),3,5,13-tetraen-16-ium + CoA.


male germ-line cyst formation

description: Formation of a group of interconnected cells derived from a single male gonial founder cell.


name: positive regulation of microglia differentiation

description: Any process that activates, maintains or increases the frequency, rate or extent of microglia differentiation, the process in which a relatively unspecialized cell acquires specialized features of a microglial cell.


name: N1-acetylspermine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity

description: Catalysis of the reaction: H2O + N(1)-acetylspermine + O2 = 3-acetamidopropanal + H2O2 + spermidine.


name: initiator methionyl aminopeptidase activity

description: Catalysis of the release of N-terminal initiator methionine from peptides.


precorrin-2 dehydrogenase activity

description: Catalysis of the reaction: NAD+ + precorrin-2 = 2 H+ + NADH + sirohydrochlorin.


name: negative regulation of nerve growth factor receptor activity

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of the nerve growth factor (NGF) receptor.


name: membrane protein proteolysis involved in retrograde protein transport, ER to cytosol

description: Any membrane protein proteolysis that is involved in retrograde protein transport, ER to cytosol.


name: metanephric descending thin limb development

description: The process whose specific outcome is the progression of the metanephric descending thin limb over time, from its formation to the mature structure. The metanephric descending thin limb is a part of the metanephric loop of Henle situated just after the proximal straight tubule (S3). It extends to the tip of the metanephric loop of Henle.


name: regulation of AV node cell action potential

description: Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in an atrioventricular node myocyte. This typically occurs via modulation of the activity or expression of voltage-gated ion channels.


name: negative regulation of inner ear receptor cell differentiation

description: Any process that stops, prevents or reduces the frequency, rate or extent of inner ear receptor cell differentiation.


name: negative regulation of meiotic cell cycle

description: Any process that stops, prevents or reduces the rate or extent of progression through the meiotic cell cycle.


nerve growth factor processing

description: The generation of a mature nerve growth factor (NGF) by proteolysis of a precursor.


histone H4 ubiquitin ligase activity

description: Catalysis of the transfer of ubiquitin to a histone H4 substrate.


description: Catalysis of the reaction: 3-keto-5-aminohexanoate + acetyl-CoA = L-3-aminobutyryl-CoA + acetoacetate.


retinal ganglion cell axon guidance

description: The process in which the migration of an axon growth cone of a retinal ganglion cell (RGC) is directed to its target in the brain in response to a combination of attractive and repulsive cues.


name: negative regulation of myoblast proliferation

description: Any process that stops, prevents or reduces the frequency, rate or extent of myoblast proliferation.


cardiac fibroblast cell differentiation

description: The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cardiac fibroblast. A cardiac fibroblast is a connective tissue cell in the heart which secretes an extracellular matrix rich in collagen and other macromolecules.


middle ear morphogenesis

description: The process in which the anatomical structures of the middle ear are generated and organized. The middle ear is the air-filled cavity within the skull of vertebrates that lies between the outer ear and the inner ear. It is linked to the pharynx (and therefore to outside air) via the Eustachian tube and in mammals contains the three ear ossicles, which transmit auditory vibrations from the outer ear (via the tympanum) to the inner ear (via the oval window).


name: negative regulation of ectoderm development

description: Any process that stops, prevents or reduces the frequency, rate or extent of ectoderm development.


description: Catalysis of the reaction: 2 raffinose = sucrose + 1F-alpha-D-galactosylraffinose.


RNA modification guide activity

description: Specifies the site of a posttranscriptional modification in an RNA molecule by base pairing with a short sequence around the target residue.


description: Catalysis of the reaction: adenosine2503 in 23S rRNA + 2 reduced [2Fe-2S]-[ferredoxin] + 2 S-adenosyl-L-methionine = 2-methyladenosine2503 in 23S rRNA + 5'-deoxyadenosine + L-methionine + 2 oxidized [2Fe-2S]-[ferredoxin] + S-adenosyl-L-homocysteine.


dihydroxyfluorene dioxygenase activity

description: Catalysis of the reaction: a dihydroxyfluorene + O2 = the corresponding 2-hydroxy-4-(oxo-1,3-dihydro-2H-inden-ylidene) but-2-enoic acid.


name: mismatch repair involved in maintenance of fidelity involved in DNA-dependent DNA replication

description: A mismatch repair process that corrects errors introduced that ensures the accuracy of DNA replication.


name: response to intra-S DNA damage checkpoint signaling

description: A process that occurs in response to signals generated as a result of intra-S DNA damage checkpoint signaling.


peptidyl-arginine N5-methylation

description: The methylation of peptidyl-arginine on the internal nitrogen-5 (N5) atom (also called delta-nitrogen) to form peptidyl-N5-methyl-L-arginine.


movement of group I intron

description: Lateral transfer of a group I intron to a homologous allele that lacks the intron, mediated by a site-specific endonuclease encoded within the mobile intron; group I introns are self-splicing introns that use guanosine as a cofactor in the splicing reaction.


name: ergothioneine biosynthesis from histidine via hercynylcysteine sulfoxide synthase

description: A biosynthetic process that results in the formation of ergothioneine from histidine via a set of steps including the hercynylcysteine sulfoxide synthase reaction, which converts N-alpha,N-alpha,N-alpha-trimethyl-L-histidine directly to hercynylcysteine sulfoxide.


sinapate ester biosynthetic process

description: The chemical reactions and pathways resulting in the formation of ester derivates of sinapate, (2E)-3-(4-hydroxy-3,5-dimethoxyphenyl)prop-2-enoate.


neutrophil mediated cytotoxicity

description: The directed killing of a target cell by a neutrophil.


cranial ganglion development

description: The process whose specific outcome is the progression of a cranial ganglion over time, from its formation to the mature structure.


name: positive regulation of stem cell differentiation

description: Any process that activates or increases the frequency, rate or extent of stem cell differentiation.


D-ribose biosynthetic process

description: The chemical reactions and pathways resulting in the formation of D-ribose, (ribo-pentose).


name: maintenance of shoot apical meristem identity

description: The process in which an organism retains a population of shoot apical meristem cells, preventing the commitment of all stem cell progeny to a differentiated cell fate.


name: negative regulation of ureter smooth muscle cell differentiation

description: Any process that stops, prevents, or reduces the frequency, rate or extent of ureter smooth muscle cell differentiation.


name: pteridine-containing compound biosynthetic process

description: The chemical reactions and pathways resulting in the formation of any compound containing pteridine (pyrazino(2,3-dipyrimidine)), e.g. pteroic acid, xanthopterin and folic acid.


behavioral defense response

description: A behavioral response seeking to protect an organism from an a perceived external threat to that organism.


citrate catabolic process to diacetyl

description: The anaerobic chemical reactions and pathways resulting in the breakdown of citrate to diacetyl, yielding energy in the form of ATP.


nephric duct formation

description: The developmental process pertaining to the initial formation of a nephric duct. A nephric duct is a tube that drains a primitive kidney.


name: branching involved in salivary gland morphogenesis

description: The process in which the branching structure of the salivary gland is generated and organized.


name: gluconate 2-dehydrogenase (acceptor) activity

description: Catalysis of the reaction: D-gluconate + acceptor = 2-dehydro-D-gluconate + reduced acceptor.


presynaptic active zone disassembly

description: The disaggregation of a presynaptic active zone into its constituent components.


meristem determinacy

description: The process in which a meristem becomes determinate (i.e. ceases to produce lateral organs and may or may not terminally differentiate).


description: Catalysis of the reaction: 1,2-dihydroxy-8-methylnaphthalene + O2 = 2-hydroxy-8-methylchromene-2-carboxylate + H+.


head kidney morphogenesis

description: The process in which the anatomical structures of the head kidney are generated and organized. The head kidney is a pronephros that consists of fused bilateral lobes located in the anterior part of the kidney.


GABA receptor activity

description: Combining with gamma-aminobutyric acid (GABA), and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. (GABA, 4-aminobutyrate) is an amino acid which acts as a neurotransmitter in some organisms.


description: Catalysis of the reaction: trans-4-(2-(3-hydroxy)-thionaphthenyl)-2-oxo-3-butenoate + H2O = pyruvate + 3-hydroxy-2-formylbenzothiophene.


embryonic neurocranium morphogenesis

description: The process in which the anatomical structures of the neurocranium are generated and organized during the embryonic phase. The neurocranium is the portion of the vertebrate skull surrounding the brain.


regulation of trichome patterning

description: Any process that modulates the frequency, rate or extent of trichome patterning.


regulation of sporulation

description: Any process that modulates the frequency, rate or extent of sporulation, the process whose specific outcome is the progression of a spore over time, from its initiation to the mature structure.


name: potassium:proton symporter activity

description: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: K+(out) + H+(out) = K+(in) + H+(in).


name: plasmacytoid dendritic cell activation involved in immune response

description: A change in the morphology or behavior of a plasmacytoid dendritic cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response.


stabilization of membrane potential

description: The accomplishment of a non-fluctuating membrane potential, the electric potential existing across any membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane.


name: detection of mechanical stimulus involved in sensory perception of wind

description: The series of events involved in the perception of wind in which a mechanical stimulus is received and converted into a molecular signal.


name: negative regulation of Schwann cell proliferation

description: Any process that decreases the frequency or extent of the multiplication or reproduction of Schwann cells, resulting in the expansion of their population. Schwann cells are a type of glial cell in the peripheral nervous system.


name: central nervous system neuron development

description: The process whose specific outcome is the progression of a neuron whose cell body is located in the central nervous system, from initial commitment of the cell to a neuronal fate, to the fully functional differentiated neuron.


geraniol dehydrogenase activity

description: Catalysis of the reaction: geraniol + NADP+ = geranial + NADPH.


name: iron-sulfur-molybdenum cofactor catabolic process

description: The chemical reactions and pathways resulting in the breakdown of iron-sulfur-molybdenum cofactor.


name: protein localization to non-growing cell tip

description: A process in which a protein is transported to, or maintained in, a location within a non-growing cell tip.


left/right axis specification

description: The establishment, maintenance and elaboration of the left/right axis. The left/right axis is defined by a line that runs orthogonal to both the anterior/posterior and dorsal/ventral axes. Each side is defined from the viewpoint of the organism rather of the observer (as per anatomical axes).


name: glutamate catabolic process via 2-oxoglutarate

description: The chemical reactions and pathways resulting in the breakdown of glutamate, via the intermediate 2-oxoglutarate.


pyrimidine dimer repair

description: The repair of UV-induced T-T, C-T and C-C dimers.


protein demethylation

description: The removal of a methyl group, from a protein amino acid. A methyl group is derived from methane by the removal of a hydrogen atom.


name: protein-DNA covalent cross-linking activity

description: Catalysis of the cross-link between a protein and a DNA abasic site, forming a thiazolidine linkage between a DNA ring-opened abasic site and the alpha-amino and sulfhydryl substituents of cysteine residue of the protein.


name: symbiont-mediated perturbation of host microtubule cytoskeleton

description: The process in which an organism effects a change that impairs the structure or function of the host microtubule cytoskeleton. The host is defined as the larger of the organisms involved in a symbiotic interaction.


name: regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response

description: Any process that modulates the frequency, rate or extent of differentiation of CD4-positive, CD25-positive, alpha-beta regulatory T cells as part of an immune response.


regulation of lung blood pressure

description: The process that modulates the force with which blood travels through the lungs. The process is controlled by a balance of processes that increase pressure and decrease pressure.


21-deoxycortisol binding

description: Binding to 21-deoxycortisol.


male pigmentation

description: Establishment of a pattern of pigment in males.


name: specification of plant organ axis polarity

description: The process in which the polarity of a plant organ axis is specified.


execution phase of necroptosis

description: A stage of the necroptotic process that starts after a necroptotic signal has been relayed to the execution machinery. Key steps of the execution phase are swelling of organelles, minor ultrastructural modifications of the nucleus (specifically, dilatation of the nuclear membrane and condensation of chromatin into small, irregular, circumscribed patches) and increased cell volume (oncosis), culminating in the disruption of the plasma membrane and subsequent loss of intracellular contents. The execution phase ends when the cell has died.


name: detection of mechanical stimulus involved in sensory perception of sound

description: The series of events involved in the perception of sound vibration in which the vibration is received and converted into a molecular signal.


primary meristem tissue development

description: The process whose specific outcome is the progression of the primary meristem over time, from formation to the mature structure, as it occurs during plant embryogenesis. The primary meristem tissue is the protoderm, ground meristem and procambium.


name: 3-geranylgeranylindole NADPH:oxygen oxidoreductase (10,11-epoxidizing) activity

description: Catalysis of the reaction: 3-geranylgeranylindole + O2 + NADPH + H+ = 10,11-epoxy-3-geranylgeranylindole + NADP + H2O.


detection of nodal flow

description: The series of events by which an endogenous stimulus is received by a cilium on a cell and converted to a molecular signal contributing to left/right asymmetry.


name: RNA endonuclease activity, producing 5'-phosphomonoesters

description: Catalysis of the hydrolysis of ester linkages within ribonucleic acids by creating internal breaks to yield 5'-phosphomonoesters.


name: response to electrical stimulus involved in regulation of muscle adaptation

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electrical stimulus. This process occurs as part of the regulation of muscle adaptation.


name: osmoregulated periplasmic glucan biosynthetic process

description: The chemical reactions and pathways resulting in the formation of osmoregulated periplasmic glucan.


bacitracin A biosynthetic process

description: The chemical reactions and pathways resulting in the formation of bacitracin A.


name: response to G1 cell size control checkpoint signaling

description: A process that occurs in response to signals generated as a result of mitotic cell cycle G1/S transition size control checkpoint signaling.


description: Catalysis of the reaction: 3-chloro-D-alanine + H2O = pyruvate + chloride + NH3.


cellular response to protozoan

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a protozoan.


name: negative regulation of kainate selective glutamate receptor signaling pathway

description: Any process that stops, prevents or reduces the frequency, rate or extent of the kainate selective glutamate receptor signaling pathway.


fatty-acyl-CoA catabolic process

description: The chemical reactions and pathways resulting in the breakdown of a fatty-acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with a fatty-acyl group.


name: TRAIL-activated apoptotic signaling pathway

description: An extrinsic apoptotic signaling pathway initiated by the binding of the ligand TRAIL (tumor necrosis factor-related apoptosis-inducing ligand) to a death receptor on the cell surface.


alveolar primary septum development

description: The progression of a primary alveolar septum over time, from its formation to the mature structure. A primary alveolar septum is a specialized epithelium that surrounds the saccule as it forms.


hypochord development

description: The process whose specific outcome is the progression of the hypochord over time, from its formation to the mature structure. The hypochord is a transient rod-like structure in the embryos of fish, lampreys and amphibians that is located immediately ventral to the notochord. The hypochord may play a role in positioning the dorsal aorta.


behavioral fear response

description: An acute behavioral change resulting from a perceived external threat.


arginyl-tRNA aminoacylation

description: The process of coupling arginine to arginyl-tRNA, catalyzed by arginyl-tRNA synthetase. The arginyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2'-OH group of an alanine accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification.


name: negative regulation of asymmetric cell division

description: Any process that stops, prevents, or reduces the frequency, rate or extent of asymmetric cell division.


L-rhamnose isomerase activity

description: Catalysis of the reaction: L-rhamnose = L-rhamnulose.