name: endoplasmic reticulum cisternal network maintenance

description: The organization process that preserves the endoplasmic reticulum (ER) cisternal network in a stable functional or structural state. The ER cisternal network is the ER part that comprises the membranes with low curvature in cross-section.


mycodextranase activity

category: biolink:MolecularActivity biolink:Occurrent biolink:OntologyClass biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: Catalysis of the endohydrolysis of 1,4-alpha-D-glucosidic linkages in alpha-D-glucans containing both 1,3- and 1,4-bonds.


GSI anchor metabolic process

category: biolink:BiologicalProcess biolink:Occurrent biolink:OntologyClass biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: The chemical reactions and pathways involving glycosylsphingolipidinositol (GSI) anchors, which attach membrane proteins to the lipid bilayer of the cell membrane.


spermine metabolic process

description: The chemical reactions and pathways involving spermine, a polybasic amine found in human sperm, in ribosomes and in some viruses, which is involved in nucleic acid packaging. Synthesis is regulated by ornithine decarboxylase which plays a key role in control of DNA replication.


name: CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation

description: The process in which a precursor cell type acquires the specialized features of a CD4-positive, CD25-positive, alpha-beta regulatory T cell.


RNA translocase activity

description: Generating a movement along a single- or double-stranded RNA molecule, driven by ATP hydrolysis.


mammary stem cell proliferation

description: The expansion of a mammary stem cell population by cell division. Mammary stem cells are a source of cells for growth of the mammary gland during puberty and gestation. These cells can give rise to both the luminal and myoepithelial cell types of the gland, and can regenerate the entire organ.


ribosome disassembly

description: The disaggregation of a ribosome into its constituent components; includes the dissociation of ribosomal subunits.


name: positive regulation of toll-like receptor 9 signaling pathway

description: Any process that activates or increases the frequency, rate, or extent of toll-like receptor 9 signaling pathway.


cellular response to monoamine stimulus

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monoamine stimulus. A monoamine is any of a group of molecular messengers that contain one amino group that is connected to an aromatic ring by ethylene group (-CH2-CH2-). Monoamines are derived from the aromatic amino acids phenylalanine, tyrosine, histidine and tryptophan.


ciliary pro-basal body maturation

description: A process that is carried out at the cellular level which results in the conversion of an immature and partially assembled ciliary pro-basal body into a mature basal body that is capable of nucleating a cilium.


name: negative regulation of hepatocyte apoptotic process

description: Any process that stops, prevents or reduces the frequency, rate or extent of hepatocyte apoptotic process.


distal tubule development

description: The process whose specific outcome is the progression of the distal tubule over time, from its formation to the mature structure. In mammals, the distal tubule is a nephron tubule that begins at the macula densa and extends to the connecting tubule.


name: negative regulation of starch metabolic process

description: Any process that stops, prevents or reduces the frequency, rate or extent of starch metabolic process.


granuloma formation

description: The formation of nodular inflammatory lesions, usually small or granular, firm, persistent, well-structured, and containing compactly grouped T lymphocytes and modified phagocytes such as epithelioid cells, giant cells, and other macrophages. Granuloma formation represents a chronic inflammatory response initiated by various infectious and noninfectious agents. The center of a granuloma consists of fused macrophages, which can become necrotic.


name: regulation of neuromuscular synaptic transmission

description: Any process that modulates the frequency, rate or extent of neuromuscular synaptic transmission.


muscle cell fate specification

description: The process in which a cell becomes capable of differentiating autonomously into a muscle cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.


simple leaf morphogenesis

description: The leaf morphogenesis process which results in the shaping of a simple leaf. A simple leaf is a leaf in which the lamina is undivided.


name: regulation of flavonol biosynthetic process

description: Any process that modulates the frequency, rate or extent of flavonol biosynthetic process.


name: cyclization of asparagine involved in intein-mediated protein splicing

description: The cyclization of asparagine to yield an L-aspartimide (otherwise known as alpha-aminosuccinimide) residue at the C-terminus of an excised intein during protein splicing.


Kupffer's vesicle development

description: The progression of the Kupffer's vesicle over time from its initial formation until its mature state. The Kupffer's vesicle is a small but distinctive epithelial sac containing fluid, located midventrally posterior to the yolk cell or its extension, and transiently present during most of the segmentation period.


name: iron incorporation into iron-sulfur cluster via tetrakis-L-cysteinyl diiron disulfide

description: The incorporation of iron into a 2Fe-2S iron-sulfur cluster via tetrakis-L-cysteinyl diiron disulfide.


name: negative regulation of synaptic transmission, glycinergic

description: Any process that stops or decreases the frequency, rate or extent of glycinergic synaptic transmission. Glycinergic synaptic transmission is the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glycine.


O antigen metabolic process

description: The chemical reactions and pathways involving the O side chain of a lipopolysaccharide, which determines the antigenic specificity of the organism. It is made up of about 50 repeating units of a branched tetrasaccharide.


chorismate synthase activity

description: Catalysis of the reaction: 5-O-(1-carboxyvinyl)-3-phosphoshikimate = chorismate + phosphate.


name: negative regulation of exo-alpha-sialidase activity

description: Any process that stops, prevents or reduces the frequency, rate or extent of exo-alpha-sialidase activity.


GDP-mannose 4,6-dehydratase activity

description: Catalysis of the reaction: GDP-alpha-D-mannose = GDP-4-dehydro-6-deoxy-alpha-D-mannose + H2O.


name: mitotic recombination-dependent replication fork processing

description: Replication fork processing that includes recombination between DNA near the arrested fork and homologous sequences. Proteins involved in homologous recombination are required for replication restart.


HRI-mediated signaling

category: biolink:Pathway biolink:OntologyClass biolink:BiologicalProcess biolink:Occurrent biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: A series of reactions in which a signal is passed on to downstream proteins within the cell via HRI (also known as EIF2AK1), an intracellular protein kinase that is activated by stress signals, such as heme deficiency, oxidative stress, osmotic shock, mitochondrial dysfunction and heat shock.


sporangiospore formation

description: The process in which sporangiospores, a type of asexual spore found in fungi, are formed. Sporangiospores are formed within sac-like structure, the sporangium, following the division of the cytoplasm.


name: 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase activity

description: Catalysis of the reaction: 4-CDP-2-C-methyl-D-erythritol + ATP = 4-CDP-2-C-methyl-D-erythritol 2-phosphate + ADP + 2 H+.


description: Catalysis of the reactions : D-galactosyl-3-(N-acetyl-beta-D-galactosaminyl)-L-serine + H2O = D-galactosyl-3-N-acetyl-beta-D-galactosamine + L-serine and D-galactosyl-3-(N-acetyl-beta-D-galactosaminyl)-L-threonyl + H2O = D-galactosyl-3-N-acetyl-beta-D-galactosamine + L-threonyl.


intestinal lipid catabolic process

description: The chemical reactions and pathways resulting in the breakdown into fatty acids and monoglycerides of lipids in the small intestine. Lipids are broken down by lipases released by the pancreas.


description: Catalysis of the transfer of N-acetylglucosamine-1-phosphate to a serine residue in a protein.


description: Catalysis of the reaction: glyoxylate + an aromatic amino acid = L-glycine + an aromatic oxo acid.


name: apigenin-7,4'-dimethyl ether 6-hydroxylase activity

description: Catalysis of the reaction: apigenin-7,4'-dimethyl ether + O2 + NADPH + H+ = ladanein + H2O + NADP.


description: Catalysis of the endohydrolysis of (1->5)-alpha-arabinofuranosidic linkages in (1->5) arabinans.


name: glutathione transmembrane transporter activity

description: Enables the transfer of glutathione, the tripeptide glutamylcysteinylglycine, from one side of a membrane to the other.


regulation of cardiac muscle adaptation

description: Any process that modulates the rate, extent or frequency of the process in which cardiac muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors.


eriodictyol 2-hydroxylase activity

description: Catalysis of the reaction: eriodictyol + NADPH + O2 + 2 H+ = 2-hydroxyeriodictyol + NADP + H2O.


allantoinase activity

description: Catalysis of the reaction: allantoin + H2O = allantoate.


peptidyl-threonine decanoylation

description: The decanoylation of peptidyl-threonine to form peptidyl-O3-decanoyl-L-threonine, typical of the protein ghrelin.


luteinizing hormone signaling pathway

description: A G protein-coupled receptor signaling pathway initiated by luteinizing hormone binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process.


MHC class Ib protein complex assembly

description: The aggregation, arrangement and bonding together of a set of components to form an MHC class Ib protein complex. Class Ib here refers to non-classical class I molecules.


name: spermidine:coumaroyl CoA N-acyltransferase activity

description: Catalysis of the transfer of a coumaroyl group to a nitrogen atom on the spermidine molecule.


name: symbiont-mediated activation of host anti-inflammatory cytokine signaling

description: A process in which a symbiont subverts an anti-inflammatory cytokine signaling pathway in the host organism by initiating, promoting, or enhancing its activation.


coenzyme F420 binding

description: Binding to F420, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes.


name: glycerol-3-phosphate transmembrane transporter activity

description: Enables the transfer of glycerol-3-phosphate from one side of a membrane to the other. Glycerol-3-phosphate is a phosphoric monoester of glycerol.


wall teichoic acid catabolic process

description: The chemical reactions and pathways resulting in the breakdown of wall teichoic acid, which is a major component of the cell wall of Gram-positive bacteria and typically consists of a polymer of glycerol-phosphate or ribitol-phosphate to which are attached glycosyl and D-alanyl ester residues and which is covalently linked to peptidoglycan.


name: positive regulation of renal sodium excretion by pressure natriuresis

description: An increase in the amount of sodium excreted in urine over a unit of time, as a result of pressure natriuresis.


methionine racemase activity

description: Catalysis of the reaction: L-methionine = D-methionine.


name: regulation of membrane repolarization during action potential

description: Any process that modulates the rate, frequency or extent of membrane repolarization during an action potential. Membrane repolarization is the process in which membrane potential changes in the repolarizing direction, towards the resting potential.


flower formation

description: The process that gives rise to the flower. This process pertains to the initial formation of a structure from unspecified parts.


(S)-usnate reductase activity

description: Catalysis of the reaction: (6R)-2-acetyl-6-(3-acetyl-2,4,6-trihydroxy-5-methylphenyl)-3-hydroxy-6-methylcyclohexa-2,4-dien-1-one + NAD+ = (S)-usnate + 2 H+ + NADH.


T cell homeostasis

description: The process of regulating the proliferation and elimination of T cells such that the total number of T cells within a whole or part of an organism is stable over time in the absence of an outside stimulus.


description: Catalysis of the reaction: H2O + an N-acetyl-beta-D-galactosalaminyl-[glycan] = N-acetyl-beta-D-galactosamine + a glycan.


GMP catabolic process

description: The chemical reactions and pathways resulting in the breakdown of GMP, guanosine monophosphate.


name: collecting lymphatic vessel constriction

description: A decrease in the diameter of collecting lymphatic vessels.


CCC codon-amino acid adaptor activity

description: A triplet codon-amino acid adaptor activity that recognizes a CCC codon.


name: thiamine-containing compound metabolic process

description: The chemical reactions and pathways involving thiamine (vitamin B1), and compounds derived from it.


name: 4-hydroxyphenylacetate transmembrane transporter activity

description: Enables the transfer of 4-hydroxyphenylacetate from one side of a membrane to the other.


lung morphogenesis

description: The process in which the anatomical structures of the lung are generated and organized.


name: negative regulation of fibronectin-dependent thymocyte migration

description: Any process that stops, prevents or reduces the frequency, rate or extent of fibronectin-dependent thymocyte migration.


name: SA node cell to atrial cardiac muscle cell signaling

description: Any process that mediates the transfer of information from an SA node cardiomyocyte to an atrial cardiomyocyte.


name: regulation of cell proliferation involved in mesonephros development

description: Any process that modulates the frequency, rate or extent of cell proliferation involved in mesonephros development.


name: regulation of response to cytokine stimulus

description: Any process that modulates the rate, frequency, or extent of a response to cytokine stimulus.


cell septum edging catabolic process

description: The chemical reactions and pathways resulting in the dissolution of the septum edging during cell separation.


description: Catalysis of the reaction: D-glucosamine + acetyl-CoA = N-acetyl-D-glucosamine + CoA + H+.


name: snoRNA transcription by RNA polymerase II

description: The synthesis of small nucleolar RNA (snoRNA) from a DNA template by RNA polymerase II, originating at an RNA polymerase II promoter.


peptidyl-lysine trimethylation

description: The methylation of peptidyl-lysine to form peptidyl-N6,N6,N6-trimethyl-L-lysine.


presynaptic membrane assembly

description: The aggregation, arrangement and bonding together of a set of components to form a presynaptic membrane, including any proteins associated with the membrane, but excluding other cellular components. A presynaptic membrane is a specialized area of membrane of the axon terminal that faces the plasma membrane of the neuron or muscle fiber with which the axon terminal establishes a synaptic junction.


name: ion channel modulating, G protein-coupled receptor signaling pathway

description: The series of molecular signals generated as a consequence of a G protein-coupled receptor binding to its physiological ligand, where the pathway proceeds through activation or inhibition of an ion channel.


name: negative regulation of cellular response to hypoxia

description: Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to hypoxia.


neural plate thickening

description: The process of apical-basal elongation of individual ectodermal cells during the formation of the neural placode.


acetyl-CoA biosynthetic process

description: The chemical reactions and pathways resulting in the formation of acetyl-CoA, a derivative of coenzyme A in which the sulfhydryl group is acetylated.


Pup conjugating enzyme activity

description: Isoenergetic transfer of Pup from one protein to another via the reaction X-Pup + Y = Y-Pup + X, where both the X-Pup and Y-Pup linkages are thioester bonds between the C-terminal amino acid of Pup and a sulfhydryl side group of a cysteine residue.


detoxification of nitrogen compound

description: Any process that reduces or removes the toxicity of nitrogenous compounds which are dangerous or toxic. This includes the aerobic conversion of toxic compounds to harmless substances.


regulation of uredinium development

description: Any process that modulates the frequency, rate or extent of uredinium development, a process that leads to the formation of a reddish, pustule-like structure formed by a rust fungus and consisting of uredospores.


sequence-specific mRNA binding

description: Binding to messenger RNA (mRNA) of a specific nucleotide composition or a specific sequence motif.


equator specification

description: The formation and development of the equator that forms the boundary between the photoreceptors in the dorsal sector of the eye and those in the ventral sector, dividing the eye into dorsal and ventral halves.


description: Catalysis of the reaction: L-methionine + thioredoxin disulfide + H2O = L-methionine (R)-S-oxide + thioredoxin.


description: Catalysis of the reaction: galactitol-1-phosphate + NAD+ = D-tagatose 6-phosphate + NADH + H+.


interleukin-21 production

description: The appearance of interleukin-21 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


name: pole plasm mitochondrial rRNA localization

description: Any process in which mitochondrial ribosomal RNA is transported to, or maintained in, the oocyte pole plasm. An example of this is found in Drosophila melanogaster.


neuromast development

description: The process whose specific outcome is the progression of the neuromast over time, from its formation to the mature structure. The neuromast is the sensory organ of the lateral line and is composed of a population of sensory hair cells, and nonsensory supporting cells and mantle cells. Neuromasts are located superficially on the epithelium or in lateral line canals.


name: positive regulation of peptide antigen transport

description: Any process that activates or increases the frequency, rate or extent of peptide antigen transport.


ether biosynthetic process

description: The chemical reactions and pathways resulting in the formation of ether.


name: detection of electrical stimulus involved in sensory perception of pain

description: The series of events that contribute to the perception of pain in which an electrical stimulus is received and converted into a molecular signal.


name: morphogenesis of larval imaginal disc epithelium

description: The process in which the anatomical structures of a larval imaginal disc epithelium are generated and organized.


inflammatory cell apoptotic process

description: Any apoptotic process in an inflammatory cell, any cell participating in the inflammatory response to a foreign substance e.g. neutrophil, macrophage.


description: Catalysis of the reaction: pyrophosphate + a 2,4-dioxotetrahydropyrimidine D-ribonucleotide = PRPP + a 2,4-dioxotetrahydropyrimidine.


name: positive regulation of distal tip cell migration

description: Any process that activates or increases the frequency, rate or extent of distal tip cell migration.


name: negative regulation of cardiac muscle hypertrophy in response to stress

description: Any process that stops, prevents or reduces the frequency, rate or extent of cardiac muscle hypertrophy in response to stress.


cyclohexane monooxygenase activity

description: Catalysis of the reaction: cyclohexane + O2 + NAD(P)H + H+ = cyclohexanol + NAD(P)+ + H2O.


response to freezing

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a freezing stimulus, temperatures below 0 degrees Celsius.


name: mesenchyme migration involved in limb bud formation

description: The migration of mesenchymal tissue that contributes to the formation of a limb bud.


description: Catalysis of the reaction: dolichyl phosphate D-mannose + protein = dolichyl phosphate + O-D-mannosylprotein.


positive regulation of DNA ligation

description: Any process that activates or increases the frequency, rate or extent of DNA ligation, the re-formation of a broken phosphodiester bond in the DNA backbone, carried out by DNA ligase.


positive regulation of urine volume

description: Any process that increases the amount of urine excreted from the body over a unit of time.


CD86 biosynthetic process

description: The chemical reactions and pathways resulting in the formation of CD86, a CD marker that occurs on antigen presenting cells that provides co-stimulatory signals necessary for T cell activation and survival.


primitive erythrocyte differentiation

description: Erythrocyte differentiation which occurs as part of the process of primitive hemopoiesis.


name: cell chemotaxis involved in Malpighian tubule morphogenesis

description: The directed movement of the outgrowing Malpighian tubule guided by specific chemical cues/signals. Movement may be towards a guidance cue (positive chemotaxis) or away from it (negative chemotaxis). Guidance contributes to the final positioning of the tubule.


oral apparatus organization

description: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the oral apparatus. The oral apparatus is a funnel-like structure used by the cell to collect food and channel it to the cytostome, characteristic of ciliate protozoans.


atrial ventricular junction remodeling

description: The reorganization or renovation of heart tissue that contributes to the maturation of the connection between an atrium and a ventricle.


name: 5'-hydroxyl dinucleotide hydrolase activity

description: Catalysis of the hydrolysis of phosphodiester bonds in 5'OH-RNA according to the reaction 5'OH-RNA + H20 = 5'OH-NpN (dinucleotide) + 5'P-RNA.


neurofilament cytoskeleton organization

description: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising neurofilaments and their associated proteins.


glycogen binding

description: Binding to glycogen.


description: Catalysis of the reaction: S-adenosyl-L-methionine + (protein)-arginine = S-adenosyl-L-homocysteine + (protein)-N-methyl-arginine.


description: Catalysis of the reaction: 2,6-dioxo-6-phenylhexanoate + NADP+ = 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate + H+ + NADPH.


name: regulation of atrial cardiac muscle cell action potential

description: Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in an atrial cardiac muscle cell contributing to the regulation of its contraction. This typically occurs via modulation of the activity or expression of voltage-gated ion channels.


name: positive regulation of posterior neural plate formation by fibroblast growth factor receptor signaling pathway

description: Any process that increases the rate or extent of the formation of the posterior neural plate, the posterior end of the flat, thickened layer of ectodermal cells known as the neural plate.


name: regulation of maltoheptaose metabolic process

description: Any process that modulates the frequency, rate or extent of maltoheptaose metabolic process.


name: sex determination, somatic-gonadal interaction

description: The process that mediates the interactions between somatic cells and gonadal cells that ultimately results in the specification of sexual status of the organism.


name: negative regulation of astrocyte differentiation

description: Any process that stops, prevents, or reduces the frequency, rate or extent of astrocyte differentiation.


name: 2-hydroxy-but-3-enyl glucosinolate biosynthetic process

description: The chemical reactions and pathways resulting in the formation of progoitrin, a 2-hydroxy-but-3-enyl glucosinolate. Glucosinolates are substituted thioglucosides found in rapeseed products and related cruciferae, and progoitrin has been implicated in causing goiters in mammals and bitter taste in cruciferous vegetables.


establishment of bipolar cell polarity

description: The specification and formation of bipolar intracellular organization or cell growth patterns. Bipolar organization is the organization that is a mirror image along an axis from a plane.


rhombomere 8 morphogenesis

description: The process in which the anatomical structure of rhombomere 8 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.


name: development of secondary female sexual characteristics

description: The process whose specific outcome is the progression of the secondary female sexual characteristics over time, from their formation to the mature structures. In female humans, these include growth of axillary and pubic hair, breast development and menstrual periods. Their development occurs in response to sex hormone secretion.


name: protein-N(PI)-phosphohistidine-galactosamine phosphotransferase system transporter activity

description: Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + galactosamine(out) = protein histidine + galactosamine phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.


name: negative regulation of intracellular steroid hormone receptor signaling pathway

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of any intracellular steroid hormone receptor signaling pathway.


name: sequestering of BMP in extracellular matrix

description: Confining a bone morphogenetic protein (BMP) to the extracellular matrix (ECM), such that it is separated from other components of the signaling pathway, including its cell surface receptor. Bone morphogenetic proteins (BMPs) are secreted as homodimers, non-covalently associated with N-terminal pro-peptides, and are targeted to the extracellular matrix through interaction with matrix proteins.


rolling hairpin viral DNA replication

description: A viral DNA replication process where a 3' hairpin structure in the viral single-stranded DNA (ssDNA) template serves as a primer for host enzymes to synthesize DNA.


catabolism by virus of host DNA

description: The breakdown of host DNA, deoxyribonucleic acid, by a virus.


name: branching involved in mammary gland cord morphogenesis

description: The process in which the branching structure of the mammary gland cord is generated and organized. The mammary gland cord is a solid epithelial structure that will hollow out, forming the mammary duct.


name: monoatomic cation efflux transmembrane transporter activity

description: Enables the transfer of a cation or cations from the inside of the cell to the outside of the cell across a membrane.


carvone reductase activity

description: Catalysis of the reaction: carvone + 2 H+ + 2 e- = dihydrocarvone.


description: Catalysis of the reaction: 2,4-dichloro-2,5-dihydro-5-oxofuran-2-acetate = 2,4-dichloro-cis,cis-muconate.


name: positive regulation of amine catabolic process

description: Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of amines.


description: Catalysis of the reaction: 17alpha-hydroxyprogesterone + O2 + reduced [NADPH--hemoprotein reductase] = 11-deoxycortisol + H+ + H2O + oxidized [NADPH--hemoprotein reductase].


plastoglobule organization

description: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the plastoglobule. Plastoglobule is a lipoprotein particle present in chloroplasts. They are rich in non-polar lipids (triglycerides, esters) as well as in prenylquinones, plastoquinone and tocopherols. Plastoglobules are often associated with thylakoid membranes, suggesting an exchange of lipids with thylakoids.


p-cresol biosynthetic process

description: The chemical reactions and pathways resulting in the formation of p-cresol.


neuroblast delamination

description: The negative regulation of cell adhesion process in which a neuroblast splits off of a neurectodermal sheet.


fructoselysine catabolic process

description: The chemical reactions and pathways resulting in the breakdown of fructoselysine.


siderophore catabolic process

description: The chemical reactions and pathways resulting in the breakdown of siderophores, low molecular weight Fe(III)-chelating substances made by aerobic or facultatively anaerobic bacteria, especially when growing under iron deficient conditions. The complexes of Fe(3+)-siderophores have very high stability constants and are taken up by specific transport systems by microorganisms; the subsequent release of iron requires enzymatic action.


L-sorbose oxidase activity

description: Catalysis of the reaction: L-sorbose + O2 = 5-dehydro-D-fructose + H2O2.


name: regulation of erythrocyte apoptotic process

description: Any process that modulates the frequency, rate or extent of erythrocyte apoptotic process.


pancreatic D cell differentiation

description: The process in which relatively unspecialized cells acquire specialized structural and functional features that characterize a pancreatic delta cell. A delta cell is a cell of the pancreas that produces somatostatin.


description: The appearance of vascular endothelial growth factor production due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


lactate racemase activity

description: Catalysis of the reaction: (S)-lactate = (R)-lactate.


tRNA acetylation

description: The modification of tRNA structure by addition of an acetyl group to tRNA. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid.


fatty acid ligase activity

description: Catalysis of the ligation of a fatty acid to an acceptor, coupled to the hydrolysis of ATP.


flavin reductase (NADH) activity

description: Catalysis of the reaction: a reduced flavin + NAD+ = an oxidized flavin + 2 H+ + NADH.


oligodendrocyte cell fate commitment

description: The process in which the developmental fate of a cell becomes restricted such that it will develop into an oligodendrocyte.


isopimaradienal hydroxylase activity

description: Catalysis of the reaction: isopimaradienal + NADPH + O2 = isopimaric acid + NADP + H2O.


rhombomere 7 development

description: The process whose specific outcome is the progression of rhombomere 7 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.


lysine carbamoyltransferase activity

description: Catalysis of the reaction: L-lysine + carbamoyl phosphate = L-homocitrulline + H+ + phosphate.


prophase

description: The cell cycle phase which is the first stage of M phase of meiosis and mitosis and during which chromosomes condense and the two daughter centrioles and their asters migrate toward the poles of the cell.


name: regulation of skeletal muscle cell differentiation

description: Any process that modulates the frequency, rate or extent of skeletal muscle cell differentiation.


protein targeting to Golgi apparatus

description: The process of targeting specific proteins to the Golgi apparatus. Usually requires an organelle-specific protein sequence motif or a protein modification (for example a palmitoylation).


name: programmed cell death involved in cell development

description: The activation of endogenous cellular processes that result in the death of a cell as part of its development.


name: positive regulation of mitotic cell cycle DNA replication

description: Any process that activates or increases the frequency, rate or extent of mitotic cell cycle DNA replication.


plasmacytoid dendritic cell activation

description: A change in the morphology or behavior of a plasmacytoid dendritic cell resulting from exposure to an activating factor such as a cellular or soluble ligand.


endodermal cell differentiation

description: The process in which a relatively unspecialized cell acquires the specialized features of an endoderm cell, a cell of the inner of the three germ layers of the embryo.


description: Catalysis of the reaction: 2-methylhexanoyl-CoA = 2-methylhex-2-enoyl-CoA + 2 H+ + e-.


name: positive regulation of synaptic vesicle recycling

description: Any process that activates or increases the frequency, rate or extent of synaptic vesicle recycling.


description: Catalyzes the reaction: UDP-alpha-D-xylose + [protein with EGF-like domain]-3-O-(beta-D-glucosyl)-L-serine = UDP + [protein with EGF-like domain]-3-O-(alpha-D-xylosyl-(1->3)-beta-D-glucosyl)-L-serine.


name: angiotensin-mediated vasodilation involved in regulation of systemic arterial blood pressure

description: The process that increases the diameter of a blood vessel via the renin-angiotensin system.


name: nuclear cell cycle DNA replication initiation

description: Any DNA replication initiation that is involved in nuclear cell cycle DNA replication.


name: methylthioribulose 1-phosphate dehydratase activity

description: Catalysis of the reaction: S-methyl-5-thio-D-ribulose 1-phosphate = 5-(methylthio)-2,3-dioxopentyl phosphate + H2O.


name: regulation of atrichoblast fate specification

description: Any process that modulates atrichoblast fate specification.


name: branched duct epithelial cell fate determination, open tracheal system

description: Allocation of a set number of cells to each primary branch in an open tracheal system, prior to the onset of cell migration. This establishes different domains of cells within the tracheal placode.


name: chemoattraction of dopaminergic neuron axon

description: The process in which a dopaminergic neuron growth cone is directed to a specific target site in response to an attractive chemical signal.


post-embryonic hemopoiesis

description: The stages of blood cell formation that take place after completion of embryonic development.


integrin biosynthetic process

description: The chemical reactions and pathways resulting in the formation of integrins, a large family of transmembrane proteins that act as receptors for cell-adhesion molecules.


name: regulation of lung goblet cell differentiation

description: Any process that modulates the frequency, rate or extent of lung goblet cell differentiation.


name: negative regulation of lipoprotein particle clearance

description: Any process that decreases the rate, frequency, or extent of lipoprotein particle clearance. Lipoprotein particle clearance is the process in which a lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.


positive regulation of hair cycle

description: Any process that activates or increases the frequency, rate or extent of the cyclical phases of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair.


description: Catalysis of the reaction: fluoroacetaldehyde + NAD+ + H2O = fluoroacetate + NADH + 2 H+.


name: glucose catabolic process to D-lactate and ethanol

description: The anaerobic chemical reactions and pathways resulting in the enzymatic breakdown of D-glucose to D-lactate and ethanol, yielding energy in the form of adenosine triphosphate (ATP) at the rate of one ATP per glucose molecule.


description: Catalysis of the reaction: indole-3-acetate + glycine + ATP(4-) = H+ + indole-3-acetyl-glycine + AMP(2-) + diphosphoric acid.


name: vascular endothelial cell response to laminar fluid shear stress

description: Any response to laminar fluid shear stress in a vascular endothelial cell.


glyoxylate cycle

description: A modification of the TCA cycle occurring in some plants and microorganisms, in which isocitrate is cleaved to glyoxylate and succinate. Glyoxylate can then react with acetyl-CoA to form malate.


name: positive regulation of potassium ion export across plasma membrane

description: Any process that activates or increases the frequency, rate or extent of potassium ion export across the plasma membrane.


alpha-cuprenene synthase activity

description: Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = (-)-alpha-cuprenene + diphosphoric acid.


name: [methyl-Co(III) methylamine-specific corrinoid protein]:coenzyme M methyltransferase activity

description: Catalysis of the reaction: [methyl-Co(III) methylamine-specific corrinoid protein] + coenzyme M = [Co(I) methylamine-specific corrinoid protein] + H+ + methyl-coenzyme M. This reaction is the transfer of the methyl group from the methylated corrinoid cofactor of a methylamine corrinoid protein to coenzyme M.


name: negative regulation of fat cell proliferation

description: Any process that stops or decreases the rate or extent of fat cell proliferation.


taste bud morphogenesis

description: The process in which the anatomical structures of the taste bud are generated and organized. The taste bud is a specialized area of the tongue that contains taste receptors.


name: NAD-dependent protein demyristoylase activity

description: Catalysis of the reaction: N6-tetradecanoyl-L-lysyl-[protein] + NAD+ + H2O = tetradecanoyl-ADP-D-ribose + L-lysyl-[protein] + nicotinamide.


allantoicase activity

description: Catalysis of the reaction: allantoate + H2O = (S)-ureidoglycolate + urea.


pinocarveol dehydrogenase activity

description: Catalysis of the reaction: pinocarveol = pinocarvone + 2 H+ + 2 e-.


high-affinity IgE receptor activity

description: Combining with high affinity with an immunoglobulin of the IgE isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


eugenol biosynthetic process

description: The chemical reactions and pathways resulting in the formation of eugenol, a colorless, aromatic, liquid hydrocarbon (C10H12O2) found in clove oil.


cranial nerve morphogenesis

description: The process in which the anatomical structure of the cranial nerves are generated and organized. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions.


name: 4,6-pyruvylated galactose residue biosynthetic process

description: The chemical reactions and pathways resulting in the formation of the pyruvylated galactose residue 4-6-O-[(R)(1-carboxyethylidine)]-Gal-beta-1,3-. The galactose residue is part of a larger polysaccharide chain.


name: D-arabinose 1-dehydrogenase [NAD(P)+] activity

description: Catalysis of the reaction: D-arabinose + NAD(P)+ = D-arabinono-1,4-lactone + NAD(P)H + H+.


cGMP-dependent protein kinase activity

description: cGMP dependent catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein.


regulation of gluconeogenesis

description: Any process that modulates the frequency, rate or extent of gluconeogenesis, the formation of glucose from noncarbohydrate precursors, such as pyruvate, amino acids and glycerol.


root hair initiation

description: The process in which a protrusion or bulge is formed at the site of plant root hair outgrowth.


name: type III site-specific deoxyribonuclease activity

description: Catalysis of the endonucleolytic cleavage of DNA to give double-stranded fragments with terminal 5'-phosphates. ATP hydrolysis is required. Cleavage is dependent on the presence of two copies of a specific recognition sequence in an inverse orientation in the DNA. Cleavage occurs at a specific distance from one of the recognition sites.


name: regulation of muscle cell apoptotic process

description: Any process that modulates the rate or frequency of muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a muscle cell and result in its death.


exochitinase activity

description: Catalysis of the hydrolysis of terminal 1,4-beta-linkages of N-acetyl-D-glucosamine (GlcNAc) polymers of chitin and chitodextrins. Typically, exochitinases progressively cleave off two subunits from the reducing or non-reducing ends of the chitin chain.


indole alkaloid metabolic process

description: The chemical reactions and pathways involving an indole alkaloid, an alkaloid containing an indole skeleton.


description: Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + chondroitin = adenosine 3',5'-bisphosphate + chondroitin 2'-O-sulfate. Results in sulfation of glucuronic acid and iduronic acid residues.


name: negative regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator

description: Any process that stops, prevents or reduces the frequency, rate or extent of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator.


central nervous system formation

description: The process that gives rise to the central nervous system. This process pertains to the initial formation of a structure from unspecified parts. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain, spinal cord and spinal nerves. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord.


prenyl-FMNH2 biosynthetic process

description: The chemical reactions and pathways resulting in prenyl-FMNH2, an essential cofactor for the decarboxylase enzymes UbiD and Fdc1.


name: CCACCA tRNA nucleotidyltransferase activity

description: Catalysis of the reaction: an unstable tRNA + 2 ATP + 4 CTP = a tRNA with a 3' CCACCA end + 6 diphosphate.


regulation of sensory perception

description: Any process that modulates the frequency, rate or extent of sensory perception, the series of events required for an organism to receive a sensory stimulus, convert it to a molecular signal, and recognize and characterize the signal.


name: nucleic acid transmembrane transporter activity

description: Enables the transfer of nucleic acids from one side of a membrane to the other. Nucleic acids are single or double-stranded polynucleotides involved in the storage, transmission and transfer of genetic information.


name: positive regulation of viral entry into host cell

description: Any process that activates or increases the frequency, rate or extent of the introduction of viral entry into the host cell.


name: chondrocyte morphogenesis involved in endochondral bone morphogenesis

description: The process in which the structures of a chondrocyte that will contribute to bone development are generated and organized.


amino-acid betaine metabolic process

description: The chemical reactions and pathways involving any betaine, the N-trimethyl derivative of an amino acid.


description: Catalysis of the reaction: 3',4',5,6-tetrahydroxy-3,7-dimethoxyflavone + S-adenosyl-L-methionine(1+) = 3',4',5-trihydroxy-3,6,7-trimethoxyflavone + S-adenosyl-L-homocysteine + H+.


berbamunine synthase activity

description: Catalysis of the reaction: (S)-N-methylcoclaurine + (R)-N-methylcoclaurine + [reduced NADPH--hemoprotein reductase] + O2 = berbamunine + [oxidized NADPH--hemoprotein reductase] + 2 H2O.


mycothiol-dependent detoxification

description: The chemical reactions using mycothiol to convert an alkylating agent to an S-conjugate of mycothiol. The latter is cleaved to release mercapturic acid which is excreted from the cell.


2-aminobenzoyl-CoA reductase activity

description: Catalysis of the reaction: 2-aminobenzoyl-CoA + 2 H+ + 2 e- = NH3 + benzoyl-CoA.


ADP-ribosylserine hydrolase activity

description: Catalysis of the reaction: (ADP-D-ribosyl)-L-seryl-[protein] + H2O = L-seryl-[protein] + ADP-ribose.


stress response to acid chemical

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis caused by the chemical structure of the anion portion of a dissociated acid (rather than the acid acting as a proton donor). The acid chemical may be in gaseous, liquid or solid form.


name: epithelial tube branching involved in lung morphogenesis

description: The process in which a highly ordered sequence of patterning events generates the branched epithelial tubes of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units.


name: negative regulation of corticotropin-releasing hormone receptor activity

description: Any process that stops, prevents or reduces the frequency, rate or extent of corticotropin-releasing hormone receptor activity.


dextranase activity

description: Catalysis of the endohydrolysis of 1,6-alpha-D-glucosidic linkages in dextran.


description: Catalysis of the reaction: 8'-apo-beta-carotenol + O2 = (E,E)-7-hydroxy-6-methylhepta-3,5-dienal + 14'-apo-beta-carotenal.


name: negative regulation of intermediate mesodermal cell fate determination

description: Any process that stops, prevents, or reduces the frequency, rate or extent of intermediate mesoderm cell fate determination.


inositol-3-phosphate synthase activity

description: Catalysis of the reaction: D-glucose 6-phosphate = 1D-myo-inositol 3-phosphate. This reaction requires NAD, which dehydrogenates the CHOH group to CO at C-5 of the glucose 6-phosphate, making C-6 into an active methylene, able to condense with the aldehyde at C-1. Finally, the enzyme-bound NADH reconverts C-5 into the CHOH form.


name: rhamnogalacturonan I backbone metabolic process

description: The chemical reactions and pathways involving the alternating alpha-(1->2)-linked rhamnose and alpha-(1->2)-linked B-galacturonic acid residues of the rhamnogalacturonan I backbone.


ribonuclease P4 activity

description: Catalysis of the endonucleolytic cleavage of RNA, removing 3'-extranucleotides from tRNA precursor.


dihydroxy-acid dehydratase activity

description: Catalysis of the reaction: 2,3-dihydroxy-3-methylbutanoate = 3-methyl-2-oxobutanoate + H2O.


name: positive regulation of macrophage proliferation

description: Any process that activates or increases the frequency, rate or extent of macrophage proliferation.


name: monoatomic cation:bicarbonate symporter activity

description: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: monoatomic cation(out) + HCO3-(out) = monoatomic cation(in) + HCO3-(in).


glucose catabolic process

description: The chemical reactions and pathways resulting in the breakdown of glucose, the aldohexose gluco-hexose.


description: Catalysis of the reaction: 5-hydroxymethylfurfural + NAD(P)H + H+ = 2,5-bis-hydroxymethylfuran + NAD(P)+.


cellular response to trehalose stimulus

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a trehalose stimulus.


17alpha-hydroxyprogesterone binding

description: Binding to 17alpha-hydroxyprogesterone.


name: negative regulation of reverse cholesterol transport

description: Any process that stops, prevents or reduces the frequency, rate or extent of reverse cholesterol transport.


detection of inactivity

description: The series of events in which a inactivity stimulus is received by a cell or organism and converted into a molecular signal.


name: regulation of type B pancreatic cell proliferation

description: Any process that modulates the frequency, rate or extent of type B pancreatic cell proliferation.


CUC codon-amino acid adaptor activity

description: A triplet codon-amino acid adaptor activity that recognizes a CUC codon.


description: Catalysis of the reaction: D-glyceraldehyde 3-phosphate + H+ + pyruvate = 1-deoxy-D-xylulose 5-phosphate + CO2.


name: entry receptor-mediated virion attachment to host cell

description: The process by which a virion attaches to a host cell by binding to a receptor on the host cell surface that mediates/triggers viral entry by endocytosis/pinocytosis or by inducing fusion/penetration.


carbon dioxide receptor activity

description: Combining with carbon dioxide to initiate a change in cell activity.


name: regulation of toll-like receptor 7 signaling pathway

description: Any process that modulates the frequency, rate, or extent of toll-like receptor 7 signaling pathway.


spindle assembly checkpoint signaling

description: A signaling process that delays the metaphase/anaphase transition until the spindle is correctly assembled and chromosomes are attached to the spindle.


RNA polyadenylation at postsynapse

description: A polyadenylation event (the enzymatic addition of a sequence of adenylyl residues at the 3' end of an RNA molecule) that takes place at a postsynapse.


globose nucleus development

description: The process whose specific outcome is the progression of the globose nucleus over time, from its formation to the mature structure.


negative regulation of T cell anergy

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell anergy.


name: protoaphin-aglucone dehydratase (cyclizing) activity

description: Catalysis of the reaction: protoaphin aglucone = H2O + xanthoaphin.


trans-geranyl-CoA isomerase activity

description: Catalysis of the reaction: trans-geranyl-CoA = cis-geranyl-CoA.


response to undecane

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an undecane stimulus.


ferroxidase activity

description: Catalysis of the reaction: 4 Fe2+ + 4 H+ + O2 = 4 Fe3+ + 2 H2O.


farnesol biosynthetic process

description: The chemical reactions and pathways resulting in the formation of the sesquiterpenoid alcohol farnesol, 3,7,11-trimethyl-2,6,10,dodecatrien-1-ol.


optic vesicle formation

description: The developmental process pertaining to the initial formation of the optic vesicle from the lateral wall of the forebrain. This process begins with the specific processes that contribute to the appearance of the vesicle and ends when the vesicle has evaginated. The optic vesicle is the evagination of neurectoderm that precedes formation of the optic cup.


protein deneddylation

description: The removal of a ubiquitin-like protein of the NEDD8 type from a protein.


name: coenzyme F420-0:L-glutamate ligase activity

description: Catalysis of the reaction: GTP + L-glutamate + factor F420-0 = GDP + H+ + factor gamma-F420-1 + phosphate.


fruit dehiscence

description: The process leading to the spontaneous opening of the fruit permitting the escape of seeds.


atrial septum intermedium development

description: The progression of the atrial septum intermedium over time, from its formation to the mature structure.


cerebellar granular layer development

description: The process whose specific outcome is the progression of the cerebellar granule layer over time, from its formation to the mature structure. The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer.


regulation of response to alcohol

description: Any process that modulates the frequency, rate or extent of response to alcohol.


ABC-type D-ribose transporter activity

description: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + D-ribose(out) = ADP + phosphate + D-ribose(in).


histone H3K18 decrotonylase activity

description: Catalysis of the reaction: H2O + N6-(2E)-butenoyl-L-lysyl-[histone H3 position 18] + NAD+ = 2''-O-(2E)-but-2-enoyl-ADP-D-ribose + L-lysyl-[histone H3] + nicotinamide.


cyclopeptine synthase activity

description: Catalysis of the reaction: anthranilate + 2 ATP + L-phenylalanine + S-adenosyl-L-methionine = 2 AMP + cyclopeptine + 2 diphosphate + 2 H+ + S-adenosyl-L-homocysteine.


name: negative regulation of alpha-beta T cell differentiation

description: Any process that stops, prevents, or reduces the frequency, rate or extent of alpha-beta T cell differentiation.


box H/ACA snoRNP complex binding

description: Binding to a box H/ACA snoRNP complex.


tRNA dihydrouridine synthesis

description: The process whereby a uridine in a transfer RNA is converted to dihydrouridine.


response to carboplatin

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carboplatin stimulus.


positive regulation of cytolysis

description: Any process that activates or increases the frequency, rate or extent of cytolysis.


root radial pattern formation

description: The radial pattern formation process that results in the formation of the different tissues of the root around its radial axis.


(-)-menthol dehydrogenase activity

description: Catalysis of the reaction: (-)-menthol + NADP+ = (2S,5R)-menthone + H+ + NADPH.


name: response to immobilization stress combined with electrical stimulus

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electrical stimulus given while being held immobile.


dGTP diphosphatase activity

description: Catalysis of the reaction: dGTP + H2O = dGMP + H+ + diphosphate.


Atg8 activating enzyme activity

description: Catalysis of the activation of the small ubiquitin-related modifier APG8, through the formation of an ATP-dependent high-energy thiolester bond.


tRNA 2'-O-methyltransferase activity

description: Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing a 2'-O-nucleotide.


name: NAD-dependent histone deacetylase activity

description: Catalysis of the reaction: histone N6-acetyl-L-lysine + H2O = histone L-lysine + acetate. This reaction requires the presence of NAD, and represents the removal of an acetyl group from a histone.


cephalosporin biosynthetic process

description: The chemical reactions and pathways resulting in the formation of a cephalosporin, any of large class of tetracyclic triterpene broad-spectrum antibiotics similar both chemically and in their mode of action to penicillin, first isolated from the culture filtrates of mediterranean fungus acremonium (cephalosporium acremonium), and effective against gram-positive bacteria.


protein-DNA ISRE complex assembly

description: The aggregation, arrangement and bonding together of proteins and DNA molecules to form a protein-DNA complex, in which the complex is formed through interaction of the protein(s) with a interferon-stimulated response element (ISRE) in the DNA.


name: regulation of action potential firing threshold

description: Any process that regulates the potential at which an axon potential is triggered.


trophectodermal cell differentiation

description: The process in which a relatively unspecialized cell acquires the specialized features of a trophectoderm cell.


name: modulation of voltage-gated sodium channel activity in another organism

description: Any process in which an organism effects a change in the frequency, rate or extent of the activity of a voltage-gated sodium channel in another organism.


name: regulation of hepatocyte differentiation

description: Any process that modulates the frequency, rate or extent of hepatocyte differentiation.


name: cellular response to sugar-phosphate stress

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the accumulation of sugar-phosphate.


embryonic meristem development

description: The process whose specific outcome is the progression of the embryonic meristem over time, from its formation to the mature structure.


euchromatin binding

description: Binding to euchromatin, a dispersed and relatively uncompacted form of chromatin.


name: protein-L-isoaspartate (D-aspartate) O-methyltransferase activity

description: Catalysis of the reaction: S-adenosyl-L-methionine + protein L-beta-aspartate = S-adenosyl-L-homocysteine + protein L-beta-aspartate methyl ester.


[2Fe-2S] cluster assembly

description: The incorporation of two iron atoms and two sulfur atoms into an iron-sulfur cluster.


4-hydroxycoumarin metabolic process

description: The chemical reactions and pathways involving 4-hydroxycoumarin.


name: protein-phycocyanobilin linkage via S-phycocyanobilin-L-cysteine

description: The linkage of the chromophore phycocyanobilin to phycocyanin or allophycocyanin via S-phycocyanobilin-L-cysteine.


name: homophytochelatin synthase (dimmer forming) activity

description: Catalysis of the reaction: glutathionate + L-gamma-glutamyl-L-cysteinyl-beta-alaninate = gamma-Glu-Cys-gamma-Glu-Cys-beta-Ala + glycine.


name: IRES-dependent translational initiation of circular RNA

description: The process where translation initiation recruits the 40S ribosomal subunits via an internal ribosome entry segment (IRES) before an AUG codon is encountered in an appropriate sequence context to initiate circular mRNA translation.


name: cellular response to zinc ion starvation

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of zinc ions.


name: symbiont-mediated perturbation of host programmed cell death

description: A process in which a symbiont gene product alters or subverts host programmed cell death, leading to a change in the frequency, rate or extent of host programmed cell death in the host cell. The host is defined as the larger of the organisms involved in a symbiotic interaction.


name: N(1),N(12)-diacetylspermine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity

description: Catalysis of the reaction: H2O + N(1),N(12)-diacetylspermine + O2 = 3-acetamidopropanal + H2O2 + N(1)-acetylspermidine.


uroporphyrinogen decarboxylase activity

description: Catalysis of the reaction: uroporphyrinogen-III = coproporphyrinogen + 4 CO2.


bud dormancy process

description: A dormancy process in which dormancy (sometimes called a dormant state) is induced, maintained or broken in a bud. Bud dormancy is a suspension of most physiological activity and growth that can be reactivated. It may be a response to environmental conditions such as seasonality or extreme heat, drought, or cold. The exit from bud dormancy is marked by the resumed growth of the bud.


name: 3,3',5-tribromobisphenol A reductive dehalogenase activity

description: Catalysis of the reaction: 3,3',5-tribromobisphenol A + 2 H+ + 2 e- = 3,3'-dibromobisphenol A + HBr.


spinal trigeminal nucleus development

description: The process whose specific outcome is the progression of the spinal trigeminal nucleus over time, from its formation to the mature structure.


gluconate 2-dehydrogenase activity

description: Catalysis of the reaction: D-gluconate + NADP+ = 2-dehydro-D-gluconate + NADPH + H+.


name: 5'-(N(7)-methyl 5'-triphosphoguanosine)-[mRNA] diphosphatase activity

description: Catalysis of the reaction: a 5'-end (N2,N2,N7-trimethyl 5'-triphosphoguanosine)-ribonucleoside in mRNA + H2O = a 5'-end diphospho-ribonucleoside in mRNA + 2 H+ + N7-methyl-GMP. Can also use (N7-methyl 5'-triphosphoguanosine)-ribonucleoside in mRNA as a substrate.


response to morphine

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a morphine stimulus. Morphine is an opioid alkaloid, isolated from opium, with a complex ring structure.


cellular response to vanadate(3-)

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vanadate(3-) stimulus.


regulation of exit from mitosis

description: Any process involved in the progression from anaphase/telophase to G1 that is associated with a conversion from high to low mitotic CDK activity.


rhamnose binding

description: Binding to the D- or L-enantiomer of rhamnose.


leukotriene A4 metabolic process

description: The chemical reactions and pathways involving leukotriene A4.


metanephric cap development

description: The biological process whose specific outcome is the progression of the metanephric cap from an initial condition to its mature state. The metanephric cap is formed by the condensation of metanephric mesenchymal cells surrounding the ureteric bud tip.


geranyltranstransferase activity

description: Catalysis of the reaction: geranyl diphosphate + isopentenyl diphosphate = 2-trans,6-trans-farnesyl diphosphate + diphosphate.


name: monounsaturated fatty acid catabolic process

description: The chemical reactions and pathways resulting in the breakdown of monounsaturated fatty acid.


name: protein localization to actin cytoskeleton

description: A process in which a protein is transported to, or maintained in, the location of an actin cytoskeleton.


name: pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity

description: Catalysis of the reaction: D-ribose 5-phosphate + D-glyceraldehyde 3-phosphate + L-glutamine = pyridoxal 5'-phosphate + L-glutamate + 3 H2O + phosphate. The reaction occurs in two steps: L-glutamine + H2O = L-glutamate + NH3, and subsequently D-ribose 5-phosphate + D-glyceraldehyde 3-phosphate + NH3 = pyridoxal 5'-phosphate + 4 H2O + phosphate.


name: 8-demethylnovobiocic acid C8-methyltransferase activity

description: Catalysis of the reaction: S-adenosyl-L-methionine + 8-desmethylnovobiocic acid = S-adenosyl-L-homocysteine + novobiocic acid + H+.


host cell extracellular matrix binding

description: Binding to the extracellular matrix of a host cell.


D-series resolvin biosynthetic process

description: The chemical reactions and pathways resulting in the formation of resolvin family D-series, hydroxy fatty acids derived from docosahexaenoic acid.


Fas signaling pathway

description: The series of molecular signals initiated by the binding of a ligand to a Fas receptor on the surface of the cell, and ending with the regulation of a downstream cellular process, e.g. transcription. Fas is a death domain-containing member of the tumor necrosis factor receptor (TNFR) superfamily.


cellular response to methylmercury

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylmercury stimulus.


protein localization to ascospore wall

description: A process in which a protein is transported to, or maintained in, a location within an ascospore wall.


response to brefeldin A

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a brefeldin A stimulus.


corrin biosynthetic process

description: The chemical reactions and pathways resulting in the formation of corrin, C19H22N4, the fundamental heterocyclic skeleton of the corrinoids. It consists of four reduced pyrrole rings joined into a macrocyclic ring. Corrin is the core of the vitamin B12 molecule.


fatty acid oxidation

description: The removal of one or more electrons from a fatty acid, with or without the concomitant removal of a proton or protons, by reaction with an electron-accepting substance, by addition of oxygen or by removal of hydrogen.


neuromast hair cell development

description: The process whose specific outcome is the progression of a neuromast hair cell over time, from its formation to the mature structure. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. Cell development does not include the steps involved in committing a cell to a specific fate.


D-lactate-2-sulfatase activity

description: Catalysis of the reaction: (R)-2-O-sulfolactate + H2O = (R)-lactate + H+ + sulfate.


description: Catalysis of the reaction: S-adenosyl-L-methionine + caffeoyl-CoA = S-adenosyl-L-homocysteine + feruloyl-CoA.


description: Catalysis of the transfer of acyl groups from an acyl-CoA to a lysophospholipid.


relaxation of muscle

description: A process in which the extent of muscle contraction is reduced. Muscle relaxation can involve a number of processes including the removal of calcium from the cytoplasm to the sarcoplasmic reticulum lumen through the action of Ca2+ ATPases. In some muscles, calcium-independent pathways also play a role in muscle relaxation by decreasing the phosphorylation state of myosin light chain.


response to mercury ion

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mercury ion stimulus.


name: nuclear receptor-mediated glucocorticoid signaling pathway

description: A nuclear receptor-mediated signaling pathway initiated by a glucocorticoid binding to an intracellular receptor of the nuclear receptor protein family, and ending with regulation of a downstream cellular process, e.g. transcription.


description: The chemical reactions and pathways involving 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane (DDT), a chlorinated broad spectrum contact insecticide.


dipyrrin metabolic process

description: The chemical reactions and pathways involving dipyrrins (pyrromethanes), compounds containing two pyrrole rings linked through a methine, -CH=, group.


carbon-halide lyase activity

description: Catalysis of the breakage of a bond between carbon and any halogen atom.


dGTP metabolic process

description: The chemical reactions and pathways involving dGTP, guanosine triphosphate.


cellular response to vitamin A

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin A stimulus.


description: Catalysis of the reaction: sn-glycerol 3-phosphate + CTP = CDP-glycerol + diphosphate.


transferrin receptor activity

description: Combining selectively with transferrin, and delivering transferrin into the cell via endocytosis. Transferrin is a major iron carrier protein in vertebrates.


name: response to glial cell derived neurotrophic factor

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glial cell derived neurotrophic factor stimulus.


name: regulation of intestinal D-glucose absorption

description: Any process that modulates the frequency, rate or extent of intestinal D-glucose absorption.


name: methionine transmembrane transporter activity

description: Enables the transfer of methionine from one side of a membrane to the other.


leukotriene biosynthetic process

description: The chemical reactions and pathways resulting in the formation of leukotriene, a pharmacologically active substance derived from a polyunsaturated fatty acid, such as arachidonic acid.


name: erythromycin C 3''-o-methyltransferase activity

description: Catalysis of the reaction: S-adenosyl-L-methionine + erythromycin C = S-adenosyl-L-homocysteine + erythromycin A + H+.


description: Catalysis of the reaction: [Molybdopterin-synthase sulfur-carrier protein]-Gly-Gly-AMP + [cysteine desulfurase]-S-sulfanyl-L-cysteine = AMP [molybdopterin-synthase sulfur-carrier protein]-Gly-NH-CH(2)-C(O)SH + cysteine desulfurase.


response to nonylphenol

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nonylphenol stimulus.


description: Catalysis of the reaction: CDP + alcohol = CMP + phosphatidyl alcohol.


name: response to spindle checkpoint signaling

description: A process that occurs in response to signals generated as a result of spindle checkpoint signaling.


name: positive regulation of L-arginine import across plasma membrane

description: Any process that activates or increases the frequency, rate or extent of L-arginine import across plasma membrane.


name: regulation of defense response to bacterium

description: Any process that modulates the frequency, rate or extent of defense response to bacterium.


name: positive regulation of intracellular cholesterol transport

description: Any process that activates or increases the frequency, rate or extent of the directed movement of cholesterol within cells.


vitamin D2 metabolic process

description: The chemical reactions and pathways involving vitamin D2, (3S,5Z,7E,22E)-9,10-secoergosta-5,7,10(19),22-tetraen-3-ol.


cytosolic valyl-tRNA aminoacylation

description: The process of coupling valine to valyl-tRNA in the cytosol, catalyzed by valyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.


name: neurotensin receptor activity, non-G protein-coupled

description: Combining with neurotensin, a neuropeptide active in the central and peripheral nervous system in mammals, and transmitting the signal from one side of the membrane to the other by a mechanism independent of coupling to G proteins.


description: Catalysis of the reaction: 6-oxo-2-hydroxy-7-(4'-chlorophenyl)-3,8,8-trichloroocta-2Z,4Z,7-trienoate + H2O = 2-(4'-chlorophenyl)-3,3-dichloropropenoate + cis-2-Hydroxy-3-chloropenta-2,4-dienone + H+.


name: regulation of mitochondrial membrane permeability involved in apoptotic process

description: Any regulation of mitochondrial membrane permeability that is involved in apoptotic process.


gibberellin-44 dioxygenase activity

description: Catalysis of the reaction: gibberellin 44 + 2-oxoglutarate + O2 = gibberellin 19 + succinate + CO2.


tubulin deacetylation

description: The removal of an acetyl group from tubulin. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid.


name: cerebellar stellate cell differentiation

description: The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature cerebellar stellate cell. Differentiation includes the processes involved in commitment of a neuroblast to a cerebellar stellate cell fate. A cerebellar stellate cell is an inhibitory GABAergic interneuron found in the cerebellar cortex.


innervation

description: The process in which a nerve invades a tissue and makes functional synaptic connection within the tissue.


name: chlorate transmembrane transporter activity

description: Enables the transfer of chlorate, ClO3-, from one side of a membrane to the other.


name: oxidoreductase activity, acting on hydrogen as donor, NAD or NADP as acceptor

description: Catalysis of an oxidation-reduction (redox) reaction in which hydrogen acts as an electron donor and reduces NAD or NADP.


name: endocytosed synaptic vesicle to endosome fusion

description: Fusion of an endocytosed synaptic vesicle with an endosome.


name: eukaryotic translation initiation factor 2alpha kinase activity

description: Catalysis of the reaction: ATP + [eukaryotic translation initiation factor 2 alpha subunit] = ADP + [eukaryotic translation initiation factor 2 alpha subunit] phosphate.


name: positive regulation of asexual reproduction

description: Any process that activates or increases the frequency, rate or extent of asexual reproduction.


name: positive regulation of toll-like receptor 21 signaling pathway

description: Any process that activates or increases the frequency, rate or extent of toll-like receptor 21 signaling pathway.


acylphosphatase activity

description: Catalysis of the reaction: an acyl phosphate + H2O = a carboxylate + phosphate.


natural killer cell proliferation

description: The expansion of a natural killer cell population by cell division.


mammary placode formation

description: The developmental process in which the mammary placode forms. The mammary placode is a transient lens shaped structure that will give rise to the mammary bud proper.


description: Catalysis of the reaction: 4-coumaryl-CoA + cyanidin 3-O-beta-D-glucoside betaine = cyanidin 3-(p-coumaroyl)-glucoside + coenzyme A.


allocryptopine 6-hydroxylase activity

description: Catalysis of the reaction: allocryptopine + NADPH + O2 + H+ = 6-hydroxy-allocryptopine + NADP + H2O.


MAP kinase kinase activity

description: Catalysis of the concomitant phosphorylation of threonine (T) and tyrosine (Y) residues in a T-X-Y motif in the activation loop of a MAP kinase (MAPK) substrate.


name: cell movement involved in somal translocation

description: The movement of a cell body from the ventricular zone to the pial surface with a concomitant shortening of the process that extends to the pial surface.


D-mannitol oxidase activity

description: Catalysis of the reaction: mannitol + O2 = mannose + H2O2.


parental behavior

description: A reproductive behavior in which a parent cares for and rears offspring.


protein insertion into plasma membrane

description: The process that results in the incorporation of a protein into a plasma membrane. Incorporation in this context means having some part or covalently attached group that is inserted into the the hydrophobic region of one or both bilayers.


name: negative regulation of brassinosteroid mediated signaling pathway

description: Any process that stops, prevents or reduces the frequency, rate or extent of brassinosteroid mediated signaling pathway.


tropane alkaloid biosynthetic process

description: The chemical reactions and pathways resulting in the breakdown of tropane alkaloids, compounds containing the 8-methyl-8-azabicyclo(3.2.1)octane ring system.


name: diterpene phytoalexin biosynthetic process

description: The chemical reactions and pathways resulting in the formation of diterpene phytoalexins, terpenoids with 20 carbons produced by plants in response to environmental stresses.


response to antipsychotic drug

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antipsychotic drug stimulus. Antipsychotic drugs are agents that control agitated psychotic behaviour, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect.


name: envenomation resulting in modulation of voltage-gated potassium channel activity in another organism

description: A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant change in the activity of a voltage-gated potassium channel in the bitten/stung organism.


name: inositol hexakisphosphate 6-kinase activity

description: Catalysis of the reaction: ATP + 1D-myo-inositol hexakisphosphate = ADP + 6-diphospho-1D-myo-inositol (1,2,3,4,5)pentakisphosphate.


description: Catalysis of the reaction: N-(5-phospho-beta-D-ribosyl)anthranilate + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + anthranilate.


cAMP catabolic process

description: The chemical reactions and pathways resulting in the breakdown of the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate).


name: cyanidin 3-O-glucoside metabolic process

description: The chemical reactions and pathways involving cyanidin 3-O-beta-D-glucoside.


MTREC complex binding

description: Binding to a MTREC complex.


name: acquisition of plant reproductive competence

description: The process in which a plant acquires the ability to respond to a floral inductive signal.


response to glycoside

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glycoside stimulus.


name: sodium-transporting ATPase activity, rotational mechanism

description: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Na+(in) -> ADP + phosphate + Na+(out), by a rotational mechanism.


description: Catalysis of the reaction: Oplophorus luciferin + O2 = oxidized Oplophorus luciferin + CO2 + hnu.


establishment of ER localization

description: The directed movement of the endoplasmic reticulum to a specific location.


name: stomach neuroendocrine cell differentiation

description: The process in which a relatively unspecialized cell acquires specialized features of a neuroendocrine cell of the stomach epithelium.


siRNA 3'-end processing

description: The process of forming the mature 3' end of a siRNA molecule.


DNA-mediated transformation

description: The direct uptake and incorporation of exogenous genetic material (DNA or RNA) into a cell from its surroundings through the cell envelope.


NK T cell differentiation

description: The process in which a precursor cell type acquires the specialized features of a NK T cell.


sporocarp development

description: The process whose specific outcome is the progression of a sporocarp over time, from its formation to the mature structure. The sporocarp is a spore bearing fruiting body organ. An example of this process is found in the Fungal species Coprinopsis cinerea.


description: The series of molecular signals initiated by interleukin-33 binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.


name: symbiont-mediated evasion of mRNA degradation by host via mRNA cap methylation

description: An innate immune response evasion mechanism in which a symbiont methylates the 2'-O-ribose of the first or second transcribed nucleotide of its mRNAs. Methylation allows evasion of the host innate immune response, which degrades cap0 (non-methylated) mRNAs. This mechanism of immune evasion is used by viruses.


regulation of response to ethanol

description: Any process that modulates the frequency, rate or extent of response to ethanol.


name: 1-alkenyl-2-acylglycerol choline phosphotransferase activity

description: Catalysis of the reaction: 1-alkenyl-2-acylglycerol + CDP-choline = plasmenylcholine + CMP.


detection of visible light

description: The series of events in which a visible light stimulus is received by a cell and converted into a molecular signal. A visible light stimulus is electromagnetic radiation that can be perceived visually by an organism; for organisms lacking a visual system, this can be defined as light with a wavelength within the range 380 to 780 nm.


urocanate hydratase activity

description: Catalysis of the reaction: 4-imidazolone-5-propanoate + H+ = trans-urocanate + H2O.


name: oxidoreductase activity, acting on a heme group of donors, nitrogenous group as acceptor

description: Catalysis of an oxidation-reduction (redox) reaction in which a heme group acts as a hydrogen or electron donor and reduces a nitrogenous group.


female pigmentation

description: Establishment of a pattern of pigment in females.


name: UDP-xylose transmembrane transporter activity

description: Enables the transfer of UDP-xylose from one side of a membrane to the other. UDP-xylose is a substance composed of xylose in glycosidic linkage with uridine diphosphate.


name: vesicle fusion with Golgi medial cisterna membrane

description: The joining of the lipid bilayer membrane around a vesicle to the lipid bilayer membrane around the Golgi medial cisterna. This can involve anterograde or retrograde transport vesicles.


chondrocyte differentiation

description: The process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte. A chondrocyte is a polymorphic cell that forms cartilage.


name: triose-phosphate transmembrane transporter activity

description: Enables the transfer of a triose phosphate from one side of a membrane to the other.


name: fatty acid in-chain hydroxylase activity

description: Catalysis of the reaction: fatty acid + O2 + 2 NADPH + H+ = fatty acid with in-chain hydroxy group + 2 NADP+ + H2O.


name: negative regulation of cell-cell adhesion mediated by integrin

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of cell-cell adhesion mediated by integrin.


name: positive regulation of intracellular steroid hormone receptor signaling pathway

description: Any process that activates or increases the frequency, rate or extent of the activity of any intracellular steroid hormone receptor signaling pathway.


neuron projection regeneration

description: The regrowth of neuronal processes such as axons or dendrites in response to their loss or damage.


name: positive regulation of anti-Mullerian hormone signaling pathway

description: Any process that activates or increases the frequency, rate or extent of anti-Mullerian hormone signaling pathway.


SUMO activating enzyme activity

description: Catalysis of the activation of the proteolytically processed small ubiquitin-related modifier SUMO, through the formation of an ATP-dependent high-energy thiolester bond.


response to type III interferon

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a type III interferon stimulus. Interferon lambda is the only member of the type III interferon found so far.


positive regulation of gastric emptying

description: Any process that increases the frequency, rate or extent of any gastric emptying process, the process in which the liquid and liquid-suspended solid contents of the stomach exit through the pylorus into the duodenum.


name: ecgonone methyl ester biosynthetic process

description: The chemical reactions and pathways resulting in the formation of ecgonone methyl ester.


brassinosteroid binding

description: Binding to a brassinosteroid.


tachykinin receptor activity

description: Combining with a tachykinin neuropeptide and transmitting the signal across the membrane by activating an associated G-protein.


2'-hydroxydaidzein reductase activity

description: Catalysis of the reaction: 2'-hydroxydihydrodaidzein + NADP+ = 2'-hydroxydaidzein + NADPH + H+.


triokinase activity

description: Catalysis of the reaction: D-glyceraldehyde + ATP = D-glyceraldehyde 3-phosphate + ADP + 2 H+.


description: Catalysis of the reaction: protocatechuate + O2 = 4-carboxy-2-hydroxymuconate semialdehyde.


name: regulation of receptor localization to synapse

description: Any process that modulates the frequency, rate or extent of receptor localization to synapse.


dimethylallyltranstransferase activity

description: Catalysis of the reaction: dimethylallyl diphosphate + isopentenyl diphosphate = diphosphate + geranyl diphosphate.


name: positive regulation of exit from mitosis

description: Any process that activates or increases the rate of progression from anaphase/telophase (high mitotic CDK activity) to G1 (low mitotic CDK activity).


response to diuretic

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diuretic stimulus. A diuretic is an agent that promotes the excretion of urine through its effects on kidney function.


retinal isomerization

description: The reactions involved in isomerization of all trans to all cis retnal.


indole alkaloid biosynthetic process

description: The chemical reactions and pathways resulting in the formation of an indole alkaloid, an alkaloid containing an indole skeleton.


thermospermine oxidase activity

description: Catalysis of the reaction: S-methyl-5'-thioadenosine + thermospermine + H+ = S-adenosyl 3-(methylthio)propylamine + spermidine.


name: peptidoglycan stem peptide endopeptidase activity

description: A peptidoglycan endopeptidase activity that acts on a stem peptide of peptidoglycan.


trochlear nerve morphogenesis

description: The process in which the anatomical structure of the trochlear nerve is generated and organized. The trochlear nerve is a motor nerve and is the only cranial nerve to exit the brain dorsally. The trochlear nerve innervates the superior oblique muscle.


glyceraldehyde oxidoreductase activity

description: Catalysis of the reaction: A + D-glyceraldehyde + H2O = (R)-glycerate + AH2 + H+.


fumonisin metabolic process

description: The chemical reactions and pathways involving fumonisin.


UV protection

description: Any process in which an organism or cell protects itself from ultraviolet radiation (UV), which may also result in resistance to repeated exposure to UV.


regulation of deacetylase activity

description: Any process that modulates the frequency, rate or extent of deacetylase activity.


name: negative regulation of mesenchymal stem cell differentiation

description: Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal stem cell differentiation.


name: regulation of circadian sleep/wake cycle, wakefulness

description: Any process that modulates the rate, frequency, or extent of the wakeful phase of the circadian sleep/wake cycle. The wakeful phase is the part of the circadian sleep/wake cycle where the organism is not asleep.


name: negative regulation of glial cell proliferation

description: Any process that stops or decreases the rate or extent of glial cell proliferation.


description: Catalysis of the reaction: UDP-galactose + lipopolysaccharide = UDP + 1,3 alpha-D-galactosyl-lipopolysaccharide.


description: Catalysis of the reaction: demethylphylloquinone + S-adenosyl-L-methionine = phylloquinone + S-adenosyl-L-homocysteine + H+.


name: hydrolase activity, acting on acid sulfur-nitrogen bonds

description: Catalysis of the hydrolysis of any acid sulfur-nitrogen bond.


name: positive regulation of smooth muscle tissue development

description: Any process that activates or increases the frequency, rate or extent of smooth muscle tissue development.


name: positive regulation of thymine transport

description: Any process that activates or increases the frequency, rate or extent of the directed movement of thymine, 5-methyluracil, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


name: regulation of type II site-specific deoxyribonuclease activity

description: Any process that modulates the frequency, rate or extent of a type II restriction endodeoxyribonuclease activity.


MutSbeta complex binding

description: Binding to a MutSbeta mismatch repair complex.


name: positive regulation of developmental pigmentation

description: Any process that increases the frequency, rate or extent of the developmental process that results in the deposition of coloring matter in an organism.


spongiotrophoblast cell proliferation

description: The multiplication or reproduction of spongiotrophoblast cells, resulting in the expansion of the population in the spongiotrophoblast layer.


description: Catalysis of the reaction: 3'-phosphoadenylylselenate + NADPH => adenosine 3',5'-bisphosphate + selenite + NADP+ + H+.


name: L-methionine biosynthetic process from O-phospho-L-homoserine and cystathionine

description: The chemical reactions and pathways resulting in the formation of L-methionine from other compounds, including O-phospho-L-homoserine and cystathionine.


name: platelet activating factor receptor activity

description: Combining with platelet activating factor to initiate a change in cell activity.


macrocin O-methyltransferase activity

description: Catalysis of the reaction: S-adenosyl-L-methionine(1+) + macrocin = S-adenosyl-L-homocysteine + H+ + tylosin.


name: regulation of osteoclast differentiation

description: Any process that modulates the frequency, rate or extent of osteoclast differentiation.


name: positive regulation of fibroblast chemotaxis

description: Any process that activates or increases the frequency, rate or extent of fibroblast chemotaxis.


name: regulation of autophagy of mitochondrion in response to mitochondrial depolarization

description: Any process that modulates the frequency, rate or extent of autophagy of mitochondrion in response to mitochondrial depolarization.


name: regulation of photoreceptor cell differentiation

description: Any process that modulates the frequency, rate or extent of photoreceptor cell differentiation. An example of this process is found in Drosophila melanogaster.


post-embryonic limb morphogenesis

description: The process, occurring after embryonic development, by which the anatomical structures of the limb are generated and organized. A limb is an appendage of an animal used for locomotion or grasping.


ribonucleotide excision repair

description: The pathway by which a ribonucleotide is removed from DNA and replaced by a deoxyribonucleotide. The ribonucleotide is incised by RNase H2, and further excised by an endonuclease. The resulting 1 nt gap is then repaired by DNA polymerase and DNA ligase.


cellular response to ceramide

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ceramide stimulus.


regulation of timing of catagen

description: Any process that modulates the frequency, rate or extent of timing of catagen, the regression phase of the hair cycle.


name: positive regulation of substrate-dependent cell migration, cell attachment to substrate

description: Any process that activates or increases the frequency, rate or extent of substrate-dependent cell migration, cell attachment to substrate.


leukotriene B4 metabolic process

description: The chemical reactions and pathways involving leukotriene B4, a leukotriene composed of (6Z,8E,10E,14Z)-eicosatetraenoic acid having (5S)- and (12R)-hydroxy substituents.


name: positive regulation of response to water deprivation

description: Any process that activates or increases the frequency, rate or extent of response to water deprivation.


2-aminoethylphosphonate binding

description: Binding to 2-aminoethylphosphonate.


farnesylcysteine lyase activity

description: Catalysis of the reaction: S-[(2E,6E)-farnesyl]-L-cysteine + O2 + H2O = (2-trans,6-trans)-farnesal + L-cysteine + hydrogen peroxide.


DNA strand invasion

description: The process in which the nucleoprotein complex (composed of the broken single-strand DNA and the recombinase) searches and identifies a region of homology in intact duplex DNA. The broken single-strand DNA displaces the like strand and forms Watson-Crick base pairs with its complement, forming a duplex in which each strand is from one of the two recombining DNA molecules.


glycerol-3-phosphate catabolic process

description: The chemical reactions and pathways resulting in the breakdown of glycerol-3-phosphate, a phosphoric monoester of glycerol.


name: regulation of inner ear auditory receptor cell fate specification

description: Any process that mediates the specification of a cell into an auditory hair cell.


description: Catalysis of the reaction: 2-hydroxy-6-oxo-6-(2-carboxyphenyl)-hexa-2,4-dienoate + H2O = cis-2-hydroxypenta-2,4-dienoate + phthalate + H+.


fatty acid alpha-oxygenase activity

description: Catalysis of the reaction: O2 + a 2,3,4-saturated fatty acid = a 2(R)-hydroperoxy fatty acid.


6-sulfoquinovose(1-) metabolic process

description: The chemical reactions and pathways involving 6-sulfoquinovose(1-).


name: positive regulation of astrocyte differentiation

description: Any process that activates or increases the frequency, rate or extent of astrocyte differentiation.


serotonergic neuron axon guidance

description: The chemotaxis process that directs the migration of an axon growth cone of a serotonergic neuron to a specific target site in response to a combination of attractive and repulsive cues.


name: pattern specification involved in pronephros development

description: Any developmental process that results in the creation of defined areas or spaces within the pronephros to which cells respond and eventually are instructed to differentiate.


name: regulation of adenylate cyclase-inhibiting opioid receptor signaling pathway

description: Any process that modulates the frequency, rate or extent of adenylate cyclase-inhibiting opioid receptor signaling pathway.


central nervous system segmentation

description: Division of the central nervous system into a series of semi-repetitive parts or segments.


cycloeucalenol cycloisomerase activity

description: Catalysis of the reaction: cycloeucalenol = obtusifoliol.


description: Catalysis of the transfer of a methyl group to an acceptor molecule, dependent on the presence of 5-methyl-5,6,7,8-tetrahydromethanopterin.


name: negative regulation of platelet aggregation

description: Any process that decreases the rate, frequency or extent of platelet aggregation. Platelet aggregation is the adhesion of one platelet to one or more other platelets via adhesion molecules.


rRNA pseudouridine synthesis

description: The intramolecular conversion of uridine to pseudouridine in an rRNA molecule.


ribonucleoprotein complex localization

description: Any process in which a ribonucleoprotein complex is transported to, or maintained in, a specific location within a cell.


name: positive regulation of epithelial cell differentiation involved in kidney development

description: Any process that activates or increases the frequency, rate or extent of epithelial cell differentiation involved in kidney development.


name: non-proteinogenic amino acid biosynthetic process

description: The chemical reactions and pathways resulting in the formation of non-proteinogenic amino acids.


dCTP diphosphatase activity

description: Catalysis of the reaction: dCTP + H2O = dCMP + H+ + diphosphate.


sabinene synthase activity

description: Catalysis of the reaction: geranyl diphosphate = sabinene + diphosphate.


name: regulation of phosphorelay signal transduction system

description: Any process that modulates the frequency, rate or extent of signal transduction via a phosphorelay signal transduction system.


name: eukaryotic translation initiation factor 2 complex assembly

description: The aggregation, arrangement and bonding together of a set of components to form an eukaryotic translation initiation factor 2 complex.


regulation of radial pattern formation

description: Any process that modulates the rate, frequency or extent of radial pattern formation, the regionalization process that results in defined areas around a point in which specific types of cell differentiation will occur.


name: pyloric sphincter smooth muscle contraction

description: A process in which force is generated within gastric smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the narrowest part of the pylorus that separates the stomach from the duodenum.


name: osmolarity-sensing monoatomic cation channel activity

description: Enables the transmembrane transfer of a monoatomic cation by a channel that opens when a change in the osmolarity occurs in the extracellular space of the cell in which the cation channel resides.


name: negative regulation of cardiac muscle cell apoptotic process

description: Any process that decreases the rate or extent of cardiac cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a cardiac muscle cell and result in its death.


name: male germ-line stem cell population maintenance

description: The process by which an organism or tissue maintains a population of male germ-line stem cells.


regulation of strand invasion

description: Any process that modulates the rate, frequency or extent of strand invasion. Strand invasion is the process in which the nucleoprotein complex (composed of the broken single-strand DNA and the recombinase) searches and identifies a region of homology in intact duplex DNA. The broken single-strand DNA displaces the like strand and forms Watson-Crick base pairs with its complement, forming a duplex in which each strand is from one of the two recombining DNA molecules.