description: The process where translation initiation recruits the 40S ribosomal subunits in a Cap and 5' end independent fashion before an AUG codon is encountered in an appropriate sequence context to initiate mRNA or circRNA translation.


mesenchymal cell development

category: biolink:BiologicalProcess biolink:Occurrent biolink:OntologyClass biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: The process aimed at the progression of a mesenchymal cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell.


detection of ethylene stimulus

description: The series of events in which an ethylene (ethene) stimulus is received by a cell and converted into a molecular signal.


ciliary vesicle assembly

description: The aggregation, arrangement and bonding together of a set of components to form a ciliary vesicle. Multiple smaller vesicles dock to the transitional fibers on a mature basal body and then fuse together to form a larger single vesicle. This then fuses with the plasma membrane and forms the ciliary membrane.


category: biolink:MolecularActivity biolink:Occurrent biolink:OntologyClass biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: Catalysis of the reaction: D-ribitol 5-phosphate + CTP = CDP-ribitol + diphosphate.


octopamine dehydratase activity

description: Catalysis of the reaction: 1-(4-hydroxyphenyl)-2-aminoethanol = (4-hydroxyphenyl)acetaldehyde + NH4.


name: negative regulation of RNA binding transcription factor activity

description: Any process that stops, prevents or reduces the frequency, rate or extent of RNA binding transcription factor activity.


galactose oxidase activity

description: Catalysis of the reaction: D-galactose + O2 = D-galacto-hexodialdose + hydrogen peroxide.


description: Catalysis of endonucleolytic cleavage of DNA in a site-specific manner, resulting in double-strand breaks.


long-day photoperiodism, flowering

description: A change from the vegetative to the reproductive phase as a result of detection of, or exposure to, a period of light that exceeds the critical day length. The critical day length varies between species. Although the term is long-day is used, most species actually respond to the duration of the night, so that the response will occur when a period of darkness falls short of the number of hours defined by 24 minus the critical day length.


name: membrane depolarization during SA node cell action potential

description: The process in which SA node cardiac muscle cell membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential.


protein targeting to chloroplast

description: The process of directing proteins towards the chloroplast, usually using signals contained within the protein. Imported proteins are synthesized as cytosolic precursors containing N-terminal uptake-targeting sequences that direct each protein to its correct subcompartment and are subsequently cleaved.


description: Catalysis of the reaction: 2 geranylgeranyl diphosphate = diphosphate + prephytoene diphosphate.


cellular response to phylloquinone

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a phylloquinone (vitamin K1) stimulus.


alpha-beta T cell proliferation

description: The expansion of an alpha-beta T cell population by cell division.


mRNA 3'-splice site recognition

description: Recognition of the intron 3'-splice site by components of the assembling U2- or U12-type spliceosome.


name: glycerol 2-dehydrogenase (NADP+) activity

description: Catalysis of the reaction: glycerol + NADP+ = glycerone + H+ + NADPH.


description: Catalysis of the reaction: 2-methylnaphthalene + NADH + O2 + H+ = 2-hydroxymethylnaphthalene + NAD+ + H2O.


muscle adaptation

description: A process in which muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities.


S-triazine hydrolase activity

description: Catalysis of the reaction: 1-halo or 1-pseudohalo-S-triazine = 1-hydroxy-S-triazine.


name: regulation of glucuronoarabinoxylan catabolic process

description: Any process that modulates the frequency, rate or extent of glucuronoarabinoxylan catabolic process.


resolution phase response

description: An active host response phase of acute inflammation driven by specialized pro-resolving mediators (SPMs) and signaling pathways, enabling timely tissue regeneration and return of function.


name: regulation of systemic arterial blood pressure by stress relaxation

description: The intrinsic circulatory process resulting from stress relaxation that modulates the force with which blood travels through the systemic arterial circulatory system. Stress relaxation is the adaptation of vessels to a new size as a result of changes in pressure in storage areas such as veins, the liver, the spleen, and the lungs.


radial pattern formation

description: The regionalization process that results in defined areas around a point in which specific types of cell differentiation will occur.


name: amino acid ligation activity by nonribosomal peptide synthase

description: Catalysis of the ligation of an amino acid to another amino acid via a carbon-nitrogen bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate, carried out by a nonribosomal peptide synthase.


name: positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure

description: Any process that activates, maintains or increases the frequency, rate or extent of heart contraction as a result of the baroreceptor response to decreased blood pressure.


name: effector-mediated modulation of host process by symbiont

description: A process mediated by a molecule secreted by a symbiont that results in the modulation (either activation or suppression) of a host structure or process. The host is defined as the larger of the organisms involved in a symbiotic interaction.


UDP-D-apiose metabolic process

description: The chemical reactions and pathways involving UDP-D-apiose, uridinediphosphoapiose, a substance composed of apiose in glycosidic linkage with uridine diphosphate.


description: Catalysis of the reaction: 4-nitrocatechol + O2 + 4 e- + 3 H+ = H2O + nitrite + 1,2,4-benzenetriol.


name: norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure

description: A process that results in an increase in the diameter of an artery during the norepinephrine-epinephrine response to blood pressure change.


regulation of lipid transport

description: Any process that modulates the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


name: positive regulation of megakaryocyte differentiation

description: Any process that activates or increases the frequency, rate or extent of megakaryocyte differentiation.


cell proliferation in forebrain

description: The creation of greater cell numbers in the forebrain due to cell division of progenitor cells.


name: G protein-coupled chemorepellent receptor activity

description: Combining with a chemorepellent and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.


name: oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor

description: Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH group acts as a hydrogen or electron donor and reduces a flavin.


name: N-acetylneuraminate 7-O(or 9-O)-acetyltransferase activity

description: Catalysis of the reaction: N-acetylneuraminate + acetyl-CoA = N-acetyl-7-O(or 9-O)-acetylneuraminate + CoA.


name: 3'-O-methyltricetin O methyl transferase activity

description: Catalysis of the reaction: S-adenosyl-L-methionine + 3'-O-methyltricetin = H+ + S-adenosyl-L-homocysteine + 3',5'-di-O-methyltricetin.


cellular response to catechin

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a catechin stimulus.


name: positive regulation of optic nerve formation

description: Any process that activates or increases the frequency, rate or extent of optic nerve formation.


regulation of nuclease activity

description: Any process that modulates the frequency, rate or extent of nuclease activity, the hydrolysis of ester linkages within nucleic acids.


name: regulation of flavonoid biosynthetic process

description: Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of flavonoids.


name: L-histidine catabolic process to glutamate and formate

description: The chemical reactions and pathways resulting in the breakdown of L-histidine into other compounds, including glutamate and formate.


alanyl-tRNA aminoacylation

description: The process of coupling alanine to alanyl-tRNA, catalyzed by alanyl-tRNA synthetase. The alanyl-tRNA synthetase is a class-II synthetases. The activated amino acid is transferred to the 3'-OH group of an alanine accetping tRNA.


name: protein O-linked glycosylation via hydroxylysine

description: The glycosylation of protein via the O5 atom of peptidyl-hydroxylysine, forming O5-glycosyl-L-hydroxylysine; the most common form is galactosyl hydroxylysine.


name: negative regulation of skeletal muscle tissue regeneration

description: Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle regeneration.


name: multi-ciliated epithelial cell differentiation

description: The process in which a relatively unspecialized cell acquires the specialized features of a multi-ciliated epithelial cell.


renal vesicle formation

description: The developmental process pertaining to the initial formation of the renal vesicle from condensed mesenchymal cells. The renal vesicle is the primordial structure of the nephron epithelium, and is formed by the condensation of mesenchymal cells.


sympathetic neuron projection guidance

description: The process in which the migration of a sympathetic neuron projection is directed to a specific target site in response to a combination of attractive and repulsive cues.


benzoate-CoA ligase activity

description: Catalysis of the reaction: ATP + benzoate + CoA = AMP + benzoyl-CoA + diphosphate.


name: norepinephrine-epinephrine catabolic process in blood stream

description: The chemical reactions and pathways resulting in the breakdown of norepinephrine or epinephrine in the bloodstream.


cinnamate reductase activity

description: Catalysis of the reaction: 3-phenylpropanoate + NAD+ = (E)-cinnamate + NADH + H+.


name: negative regulation of skeletal muscle hypertrophy

description: Any process that stops, prevents or reduces the frequency, rate or extent of skeletal muscle hypertrophy.


name: molybdopterin cofactor metabolic process

description: The chemical reactions and pathways involving the molybdopterin cofactor (Moco), essential for the catalytic activity of some enzymes, e.g. sulfite oxidase, xanthine dehydrogenase, and aldehyde oxidase. The cofactor consists of a mononuclear molybdenum (Mo-molybdopterin) or tungsten ion (W-molybdopterin) coordinated by one or two molybdopterin ligands.


name: transcription open complex formation at RNA polymerase II promoter

description: Any process involved in the melting of the DNA hybrid of the core promoter region within the transcriptional closed complex of an RNA polymerase II preinitiation complex (PIC) to produce an open complex where the DNA duplex around the transcription initiation site is unwound to form the transcription bubble.


cerebellar basket cell differentiation

description: The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature cerebellar basket cell. Differentiation includes the processes involved in commitment of a neuroblast to a cerebellar basket cell fate. A cerebellar basket cell is an inhibitory GABAergic interneuron found in the cerebellar cortex.


description: The chemical reactions and pathways involving poly(3-hydroxyalkanoates), polyesters of 3-hydroxyacids produced as intracellular granules by a large variety of bacteria.


glycosylceramidase activity

description: Catalysis of the reaction: glycosyl-N-acylsphingosine + H2O = a sugar + N-acylsphingosine.


uracil dehydrogenase activity

description: Catalysis of the reaction: uracil + acceptor = barbiturate + reduced acceptor.


name: cell communication by electrical coupling involved in cardiac conduction

description: The process that mediates signaling interactions between one cell and another cell by transfer of current between their adjacent cytoplasms via intercellular protein channels and contributes to the process of cardiac conduction.


name: keto-3-deoxy-D-manno-octulosonic acid metabolic process

description: The chemical reactions and pathways involving keto-3-deoxy-D-manno-octulosonic acid, an acidic sugar present in lipopolysaccharides of the outer membranes of some Gram-negative bacteria.


name: paraxial mesodermal cell fate commitment

description: The process in which a cell becomes committed to become a paraxial mesoderm cell.


name: negative regulation of axial mesodermal cell fate determination

description: Any process that stops, prevents, or reduces the frequency, rate or extent of axial mesoderm cell fate determination.


description: Remodeling the acyl chains of phosphatidylglycerol, through sequential deacylation and re-acylation reactions, to generate phosphatidylglycerol containing different types of fatty acid acyl chains.


saponin biosynthetic process

description: The chemical reactions and pathways resulting in the formation of saponins, glycosides of plants in which the aglycan (sapogenin) group is a terpene or steroid and the sugar group is a glucose, a galactose, a pentose, a methylpentose or an oligosaccharide. Saponins are powerful surfactant agents and membrane active; they are, hence, toxic to animals on injection.


name: abscisic acid glucose ester beta-glucosidase activity

description: Catalysis of the reaction: abscisic acid glucose ester + H2O = abscisic acid + beta-D-glucose.


name: positive regulation of phosphatidylethanolamine metabolic process

description: Any process that activates or increases the frequency, rate or extent of phosphatidylethanolamine metabolic process.


serine-tRNA ligase activity

description: Catalysis of the reaction: ATP + L-serine + tRNA(Ser) = AMP + diphosphate + L-seryl-tRNA(Ser).


oviduct morphogenesis

description: The process in which anatomical structures of the oviduct are generated and organized. An oviduct is a tube through which an ova passes from the ovary to the uterus, or from the ovary to the outside of the organism.


alanopine dehydrogenase activity

description: Catalysis of the reaction: 2,2'-iminodipropanoate + H2O + NAD+ = L-alanine + H+ + NADH + pyruvate.


name: positive regulation of muscle cell differentiation

description: Any process that activates or increases the frequency, rate or extent of muscle cell differentiation.


ceramide transfer activity

description: Removes a ceramide from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle.


description: The chemical reactions and pathways resulting in the formation of (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds.


(25S)-Delta(4)-dafachronate binding

description: Binding to (25S)-Delta(4)-dafachronate.


name: subpallium cell proliferation in forebrain

description: The multiplication or reproduction of subpallium cells in the forebrain, resulting in the expansion of a cell population.


name: negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning

description: Any process that stops, prevents or reduces the frequency, rate or extent of smoothened signaling pathway involved in dorsal/ventral neural tube patterning.


rRNA acetylation

description: The modification of rRNA structure by addition of an acetyl group to rRNA. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid.


name: thyroid-stimulating hormone-secreting cell development

description: The process whose specific outcome is the progression of a thyroid-stimulating hormone-secreting cell over time, from its formation to the mature structure. A thyroid-stimulating hormone-secreting cell is a basophil cell of the anterior pituitary that produces thyroid stimulating hormone, thyrotrophin.


description: Catalysis of the reaction: IMP + diphosphate = hypoxanthine + 5-phospho-alpha-D-ribose 1-diphosphate.


UDP-rhamnose biosynthetic process

description: The chemical reactions and pathways resulting in the formation of UDP-L-rhamnose, a substance composed of rhamnose in glycosidic linkage with uridine diphosphate.


regulation of norepinephrine uptake

description: Any process that modulates the frequency, rate or extent of the directed movement of the neurotransmitter norepinephrine into a cell.


name: regulation of serine C-palmitoyltransferase activity

description: Any process that modulates the frequency, rate or extent of serine C-palmitoyltransferase activity.


name: iron incorporation into iron-sulfur cluster via tris-L-cysteinyl L-arginyl diiron disulfide

description: The incorporation of iron into a 4Fe-4S iron-sulfur cluster via tris-L-cysteinyl L-arginyl diiron disulfide.


inositol biosynthetic process

description: The chemical reactions and pathways resulting in the formation of inositol, 1,2,3,4,5,6-cyclohexanehexol, a growth factor for animals and microorganisms.


name: symbiont-mediated disruption of host cell-cell adhesion

description: A process in which a symbiont alters or subverts host cell adhesion ito its extracellular matrix. The host is defined as the larger of the organisms involved in a symbiotic interaction.


name: negative regulation of turning behavior involved in mating

description: Any process that decreases the rate, frequency or extent of turning behavior involved in mating. Turning behavior is the sharp ventral turn performed by the male as he approaches either the hermaphrodite head or tail, whilst trying to locate his partner's vulva. Turning occurs via a sharp ventral coil of the male's tail.


neoxanthin synthase activity

description: Catalysis of the reaction: all-trans-violaxanthin = all-trans-neoxanthin.


chaeta morphogenesis

description: The process in which the anatomical structures of the chaeta are generated and organized. A chaeta is a sensory multicellular cuticular outgrowth of a specifically differentiated cell.


name: urate transmembrane transporter activity

description: Enables the transfer of urate from one side of a membrane to the other. Urate is the anion of uric acid, 2,6,8-trioxypurine, the end product of purine metabolism in certain mammals and the main excretory product in uricotelic animals.


name: reduced coenzyme F420:quinone oxidoreductase activity

description: Catalysis of the reaction: reduced coenzyme F420 + 2,3-dimethyl-1,4-naphthoquinone = coenzyme F420 + reduced 2,3-dimethyl-1,4-naphthoquinone. Reduced 2,3-dimethyl-1,4-naphthoquinone is also known as 2,3-dimethyl-1,4-hydronaphthoquinone.


name: GTP-dependent polyribonucleotide 5'-hydroxyl-kinase activity

description: Catalysis of the reaction: GTP + 5'-dephospho-RNA = GDP + 5'-phospho-RNA.


name: CoB--CoM heterodisulfide reductase activity

description: Catalysis of the reaction: coenzyme B + coenzyme M + methanophenazine = N-{7-[(2-sulfoethyl)dithio]heptanoyl}-3-O-phospho-L-threonine + dihydromethanophenazine.


description: The formylation of the N-terminal proline of proteins to form the derivative N-formylproline.


name: protoheme IX farnesyltransferase activity

description: Catalysis of the reaction: protoheme IX + (2E,6E)-farnesyl diphosphate + H2O = heme O + diphosphate.


name: regulation of establishment or maintenance of cell polarity

description: Any process that modulates the frequency, rate or extent of the specification, formation or maintenance of anisotropic intracellular organization or cell growth patterns.


name: negative regulation of entry into reproductive diapause

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the dormancy process that results in entry into reproductive diapause. Reproductive diapause is a form of diapause where the organism itself will remain fully active, including feeding and other routine activities, but the reproductive organs experience a tissue-specific reduction in metabolism, with characteristic triggering and releasing stimuli.


name: mesonephric glomerulus vasculature morphogenesis

description: The process in which the anatomical structures of the mesonephric glomerulus vasculature are generated and organized. The mesonephric glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the mesonephric glomerulus.


name: agglutination involved in conjugation with cellular fusion

description: The aggregation or adhesion of compatible mating types via complementary cell-cell interactions during conjugation with cellular fusion of a unicellular organism. An example of this process is agglutination in Saccharomyces cerevisiae.


sequestering of mercury

description: The process of binding or confining toxic mercury ions or atoms such that they are separated from sensitive components of a biological system.


glycolipid transfer activity

description: Removes a glycolipid from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle. A glycolipid is a compound usually containing 1-4 linked monosaccharide residues joined by a glycosyl linkage to a lipid.


phenylmercury acetate catabolic process

description: The chemical reactions and pathways resulting in the breakdown of phenylmercury acetate, an organomercurial compound composed of a mercury atom attached to a benzene ring and an acetate group.


name: regulation of cardiac endothelial to mesenchymal transition

description: Any process that modulates the frequency, rate or extent of cardiac endothelial to mesenchymal transition.


peptidyl-tryptophan modification

description: The chemical alteration of a tryptophan residue in a peptide.


name: cerebellar Purkinje cell layer maturation

description: A developmental process, independent of morphogenetic (shape) change, that is required for the cerebellar Purkinje cell layer to attain its fully functional state. The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar cortex through axons that project into the white matter. Extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells.


name: [tyrosine 3-monooxygenase] kinase activity

description: Catalysis of the reaction: ATP + [tyrosine-3-monooxygenase] = ADP + phospho-[tyrosine-3-monooxygenase].


inferior olivary nucleus maturation

description: A developmental process, independent of morphogenetic (shape) change, that is required for the inferior olivary nucleus to attain its fully functional state. The inferior olivary nucleus is a capsule-shaped structure in the ventral medulla located just lateral and dorsal to the medullary pyramids. Neurons in the inferior olivary nucleus are the source of climbing fiber input to the cerebellar cortex; these neurons have been implicated in various functions, such as learning and timing of movements.


pulmonary valve development

description: The progression of the pulmonary valve over time, from its formation to the mature structure.


regulation of flocculation

description: Any process that modulates the rate, frequency or extent of the non-sexual aggregation of single-celled organisms.


pyridoxal oxidase activity

description: Catalysis of the reaction: pyridoxal + H2O + O2 = 4-pyridoxate + hydrogen peroxide.


AUA codon-amino acid adaptor activity

description: A triplet codon-amino acid adaptor activity that recognizes an AUA codon.


name: trichloro-p-hydroquinone reductive dehalogenase activity

description: Catalysis of the reaction: 2,3,6-trichlorohydroquinone + 2 glutathione = 2,6-dichlorohydroquinone + glutathione disulfide + HCl.


immunoglobulin receptor activity

description: Combining with the Fc region of an immunoglobulin protein and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


name: response to triacyl bacterial lipopeptide

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a triacylated bacterial lipopeptide stimulus.


name: negative regulation of glycogen (starch) synthase activity

description: Any process that stops, prevents or reduces the frequency, rate or extent of glycogen (starch) synthase activity.


cellular response to pH

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus. pH is a measure of the acidity or basicity of an aqueous solution.


description: Catalysis of the reaction: 2,6-dihydroxybenzothiazole + 1/2 O2 = 2,6,7-trihydroxybenzothiazole.


glomerulus vasculature morphogenesis

description: The process in which the anatomical structures of the glomerulus vasculature are generated and organized. The glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the glomerulus.


dicarboxylic acid biosynthetic process

description: The chemical reactions and pathways resulting in the formation of dicarboxylic acids, any organic acid containing two carboxyl (-COOH) groups.


positive regulation of heart looping

description: Any process that activates or increases the frequency, rate or extent of heart looping.


prephenate(2-) biosynthetic process

description: The chemical reactions and pathways resulting in the formation of prephenate(2-).


name: cellular response to cell envelope stress

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stress acting at the cell envelope.


NADPH dehydrogenase activity

description: Catalysis of the reaction: NADPH + H+ + acceptor = NADP+ + reduced acceptor.


description: Catalysis of the reaction: 2-oxo-8-methylthiooctanoate + acetyl-CoA + H2O = H+ + 2-(6'-methylthio)hexylmalate + coenzyme A.


acetoacetyl-ACP synthase activity

description: Catalysis of the reaction: acetyl-CoA + malonyl-CoA + H+ + a holo-[acyl-carrier protein] = acetoacetyl-ACP + 2 coenzyme A + carbon dioxide.


name: siRNA-mediated retrotransposon silencing by mRNA destabilization

description: A retrotransposon silencing mechanism in which mRNAs transcribed from transposons are targeted for degradation by a siRNA.


retrotransposon silencing

description: Any process that decreases the frequency, rate or extent of retrotransposition. Retrotransposons are a subset of transposable elements that use an RNA intermediate and reverse transcribe themselves into the genome.


name: response to cell cycle checkpoint signaling

description: A process that occurs in response to signals generated as a result of cell cycle checkpoint signaling.


cardiac muscle cell action potential

description: An action potential that occurs in a cardiac muscle cell.


name: negative regulation of relaxation of cardiac muscle

description: Any process that stops, prevents or reduces the frequency, rate or extent of relaxation of cardiac muscle.


cellular response to fluid shear stress

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fluid shear stress stimulus. Fluid shear stress is the force acting on an object in a system where the fluid is moving across a solid surface.


glial cell fate specification

description: The process in which a cell becomes capable of differentiating autonomously into a glial cell in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed.


labyrinthine layer morphogenesis

description: The process in which the labyrinthine layer of the placenta is generated and organized.


forebrain generation of neurons

description: The process in which nerve cells are generated in the forebrain. This includes the production of neuroblasts from and their differentiation into neurons.


name: maintenance of secretory granule location

description: Any process in which a secretory granule is maintained in a specific location within a cell and prevented from moving elsewhere.


root cap development

description: The process whose specific outcome is the progression of the root cap over time, from its formation to the mature structure. The root cap protects the root meristem from friction as the root grows through the soil. The cap is made up of a group of parenchyma cells which secrete a glycoprotein mucilage as a lubricant.


name: 2-hydroxyeriodictyol 6C-glucoside dehydratase activity

description: Catalysis of the reaction: 6C-beta-D-glucosyl-2-hydroxyeriodictyol = isoorientin + H2O.


name: negative regulation of activated CD8-positive, alpha-beta T cell apoptotic process

description: Any process that stops, prevents or reduces the frequency, rate or extent of activated CD8-positive, alpha-beta T cell apoptotic process.


name: phosphate:acyl-[acyl carrier protein] acyltransferase activity

description: Catalysis of the reaction: a fatty acyl-[acyl-carrier protein] + orthophosphate = acyl phosphate + [acyl-carrier protein].


name: positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway

category: biolink:Pathway biolink:OntologyClass biolink:BiologicalProcess biolink:Occurrent biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: The series of molecular signals initiated by vascular endothelial growth factor (VEGF) binding to a platelet-derived growth factor receptor (PDGFR) on the surface of a cell, which activates or increases the frequency, rate or extent of cell proliferation.


name: negative regulation of austinol biosynthetic process

description: Any process that stops, prevents or reduces the frequency, rate or extent of austinol biosynthetic process.


name: multiple spine synapse organization, multiple dendrites

description: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a synapse between a multiple synapse bouton and two or more dendritic spines protruding either from a single dendrite or from multiple dendrites.


positive regulation of bone remodeling

description: Any process that activates or increases the frequency, rate or extent of bone remodeling.


polyketide synthase activity

description: Catalysis of a multistep reaction that produce polyketides through decarboxylative condensation of carboxylic acids. The key chain-building reaction, a C-N bond-forming reaction, involves the generation of the characteristic peptide bond by nucleophilic attack of the amino group of an amino-acyl donor unit covalently bound to a downstream peptidyl carrier protein module (amino acyl-S-PCP) on the acyl group of an upstream electrophilic acyl- or peptidyl acyl-S-PCP chain, catalyzed by a condensation (C) domain. Supplementing these core chain-elongation domains are variable numbers of auxiliary domains that are responsible for modification of the growing polypeptide chain by a small set of iterated reactions including epimerization, N-methylation, and heterocyclization.


pentanamidase activity

description: Catalysis of the reaction: H2O + pentanamide = NH4 + valerate.


tRNA m2,2-guanine biosynthesis

description: The process whereby a guanine residue in a transfer RNA is methylated twice at the N2 position.


name: canonical Wnt signaling pathway involved in heart development

description: The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that contributes to the progression of the heart over time. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes.


name: regulation of mitotic cell cycle DNA replication

description: Any process that modulates the frequency, rate or extent of mitotic cell cycle DNA replication.


name: negative regulation of xylan catabolic process

description: Any process that stops, prevents or reduces the frequency, rate or extent of xylan catabolic process.


name: termination of RNA polymerase III transcription

description: A transcription termination process that completes the production of a primary RNA polymerase II transcript. RNA polymerase III has an intrinsic ability to terminate transcription upon incorporation of at least 4 contiguous U residues.


inner ear receptor cell development

description: The process whose specific outcome is the progression of an inner ear receptor cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.


name: negative regulation of endodermal cell fate specification

description: Any process that restricts, stops or prevents a cell from specifying into an endoderm cell.


otolith mineralization

description: The precipitation of specific crystal forms of calcium carbonate with extracellular matrix proteins in the otolith organs of the vertebrate inner ear.


name: positive regulation of myeloid cell apoptotic process

description: Any process that activates or increases the frequency, rate, or extent of myeloid cell apoptotic process.


solanapyrone synthase activity

description: Catalysis of the cyclization of double bonds in prosolanapyrone II to form (-)-solanapyrone A.


name: ATPase-coupled monocarboxylic acid transmembrane transporter activity

description: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + monocarboxylic acid(out/in) = ADP + phosphate + monocarboxylic acid(in/out).


snRNA modification guide activity

description: Specifies the site of a posttranscriptional modification in an snRNA molecule by base pairing with a short sequence around the target residue.


description: Catalysis of the hydrolysis of the terminal alpha-D-mannose residues in oligo-mannose oligosaccharides.


name: efferent axon development in anterior lateral line nerve

description: The process whose specific outcome is the progression of an efferent axon in the anterior lateral line nerve over time from its formation to the mature structure. This process includes axonogenesis and pathfinding of the efferent axons in the anterior lateral line nerve.


GPCR taste receptor activity

description: A G protein-coupled receptor activity that is responsible for the sense of taste.


name: oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor

description: Catalysis of an oxidation-reduction (redox) reaction in which a phosphorus- or arsenic-containing group acts as a hydrogen or electron donor and reduces a disulfide.


name: negative regulation of lateral mesodermal cell fate specification

description: Any process that stops, prevents, or reduces the frequency, rate or extent of lateral mesoderm cell fate specification.


description: H2O + L-glutamate 5-semialdehyde + NAD+ = 2 H+ + L-glutamate + NADH.


dendritic cell cytokine production

description: Any process that contributes to cytokine production by a dendritic cell.


description: Remodeling the acyl chains of phosphatidylethanolamine, through sequential deacylation and re-acylation reactions, to generate phosphatidylethanolamine containing different types of fatty acid acyl chains.


phytanate-CoA ligase activity

description: Catalysis of the reaction: ATP + CoA + phytanate = AMP + diphosphate + H+ + phytanoyl-CoA.


name: positive regulation of nutrient release by host

description: Any process in which an organism activates, maintains or increases the frequency, rate or extent of the release of nutrients from its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.


cell redox homeostasis

description: Any process that maintains the redox environment of a cell or compartment within a cell.


interleukin-5 production

description: The appearance of interleukin-5 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


cellular response to quercetin

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a quercetin stimulus.


name: cleavage of bicistronic rRNA transcript (SSU-rRNA, LSU-rRNA)

description: Endonucleolytic cleavage of pre-rRNAs originally produced as a bicistronic rRNA transcript that contains the SSU-rRNA and the LSU-rRNA in that order from 5' to 3' along the primary transcript. Primary ribosomal RNA transcripts with two genes in this order are produced in Archaeal species.


palmitic acid metabolic process

description: The chemical reactions and pathways involving palmitic acid.


description: Catalysis of the reaction: Catalysis of the reaction: S-adenosyl-L-methionine + uridine44 in tRNASer = 2'-O-methyluridine44 in tRNASer + H+ + S-adenosyl-L-homocysteine.


name: defense response by callose deposition in cell wall

description: Any process in which callose is transported to, and/or maintained in, the cell wall during the defense response. Callose is a linear 1,3-beta-d-glucan formed from UDP-glucose and is found in certain plant cell walls.


name: positive regulation of cyclodextrin metabolic process

description: Any process that activates or increases the frequency, rate or extent of cyclodextrin metabolic process.


leucoanthocyanidin biosynthetic process

description: The chemical reactions and pathways resulting in the formation of leucoanthocyanidins, a class of colorless intermediates in the biosynthetic pathway of the pigmented flavonoids.


maintenance of unfolded protein

description: Maintaining a protein in an unfolded, soluble state.


name: negative regulation of epithelial cell differentiation

description: Any process that stops, prevents, or reduces the frequency, rate or extent of epithelial cell differentiation.


B-1b B cell differentiation

description: The process in which B cells acquire the specialized features of B-1b B cells. B-1b B cells are B-1 cells that do not express CD5.


name: oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor

description: Catalysis of an oxidation-reduction (redox) reaction in which a CH2 group acts as a hydrogen or electron donor and reduces NAD+ or NADP.


atrioventricular canal morphogenesis

description: The developmental process by which an atrioventricular canal is generated and organized.


mannose catabolic process

description: The chemical reactions and pathways resulting in the breakdown of mannose, the aldohexose manno-hexose, the C-2 epimer of glucose.


name: regulation of dendritic cell antigen processing and presentation

description: Any process that modulates the frequency, rate, or extent of dendritic cell antigen processing and presentation.


outer stripe development

description: The process whose specific outcome is the progression of the outer stripe over time, from its formation to the mature structure. The outer stripe is the region of the kidney outer medulla that lies just below the cortex. The proximal straight tubules (S3) characterize this region.


description: Catalysis of the reaction: 4-hydroxybenzoyl-CoA + H2O = 4-hydroxybenzoate + CoA + H+.


name: negative regulation of methanofuran metabolic process

description: Any process that stops, prevents or reduces the frequency, rate or extent of methanofuran metabolic process.


bisphenol A hydroxylase B activity

description: Catalysis of the reaction: bisphenol A + NADH + H+ + O2 = 1,2-bis(4-hydroxyphenyl)-2-propanol + NAD+ + H2O.


lipoprotein lipid oxidation

description: The modification of a lipoprotein by oxidation of the lipid group.


sulfinoalanine decarboxylase activity

description: Catalysis of the reaction: 3-sulfino-L-alanine = hypotaurine + CO2.


glycine reductase activity

description: Catalysis of the reaction: acetyl phosphate + H2O + NH4 + thioredoxin disulfide = glycine + H+ + phosphate + thioredoxin.


positive regulation of viral process

description: Any process that activates or increases the frequency, rate or extent of a multi-organism process in which a virus is a participant.


heme catabolic process

description: The chemical reactions and pathways resulting in the breakdown of heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring.


name: negative regulation of mitotic spindle pole body separation

description: Any process that decreases the rate, frequency or extent of the process involving the release of duplicated mitotic spindle pole bodies (SPBs) and their migration away from each other within the nuclear membrane.


D-lysine oxidase activity

description: Catalysis of the reaction: D-lysine + O2 + H2O = 6-amino-2-oxohexanoate + NH3 + hydrogen peroxide.


dense core granule priming

description: A process that converts unprimed dense core granules (DCVs) to a pool of primed vesicles that are capable of fusing with the plasma membrane (fusion-competent) and thereby releasing their contents. Priming typically occurs after docking.


name: specification of mesonephric distal tubule identity

description: The process in which the distal tubule of the mesonephric nephron acquires its identity.


name: spinal cord ventral commissure morphogenesis

description: The process in which the anatomical structures of the spinal cord ventral commissure are generated and organized.


name: inner nuclear membrane-associated protein degradation pathway

description: A protein quality control pathway that removes ubiquitinated proteins from the nuclear inner membrane before transferring them to the proteasome for degradation.


name: positive regulation of heart rate by neuronal norepinephrine

description: The process in which the secretion of norepinephrine released from nerve endings increases the rate of heart muscle contraction.


regulation of ERK5 cascade

description: Any process that modulates the frequency, rate or extent of signal transduction mediated by the ERK5 cascade.


name: negative regulation of monocyte extravasation

description: Any process that stops, prevents or reduces the frequency, rate or extent of monocyte extravasation.


cellotetraose binding

description: Binding to a cellotetraose, an oligosaccharide consisting of four glucose residues resulting from hydrolysis of cellulose.


name: trinitrophenol dihydride denitratase activity

description: Catalysis of the reaction: trinitrophenol dihydride Meisenheimer complex (aci form) = 2,4-dinitrophenol hydride Meisenheimer complex + NO2. Trinitrophenol is also known as TNP and dinitrophenol is also known as DNP.


name: olfactory bulb interneuron differentiation

description: The process in which a neuroblast acquires specialized features of an interneuron residing in the olfactory bulb.


D-amino-acid oxidase activity

description: Catalysis of the reaction: a D-amino acid + H2O + O2 = a 2-oxo acid + NH3 + hydrogen peroxide.


name: positive regulation of paraxial mesodermal cell fate specification

description: Any process that activates or increases the frequency, rate or extent of paraxial mesoderm cell fate specification.


description: Catalysis of the reaction: (2E,4E)-2-hydroxyhexa-2,4-dienoate + H2O = 4-hydroxy-2-oxohexanoate.


alcohol O-decanoyltransferase activity

description: Catalysis of the reaction: decanoyl-CoA + an alcohol = CoA + a decyl ester.


eisosome assembly

description: The aggregation, arrangement and bonding together of a set of components to form an eisosome, a cell part that is composed of the eisosome membrane and eisosome filaments. The eisosome membrane, also called the MCC domain, is a furrow-like plasma membrane sub-domain with associated integral transmembrane proteins. The eisosome filaments form a scaffolding lattice on the cytoplasmic face of the membrane.


name: positive regulation of relaxation of smooth muscle

description: Any process that activates or increases the frequency, rate or extent of relaxation of smooth muscle.


cellulose binding

description: Binding to cellulose.


name: isoprenoid biosynthetic process via 1-deoxy-D-xylulose 5-phosphate

description: The chemical reactions and pathways resulting in the formation of isoprenoid via 1-deoxy-D-xylulose 5-phosphate.


name: envenomation resulting in modulation of calcium channel activity in another organism

description: A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant change in the activity of a calcium channel in the bitten organism.


name: regulation of type I site-specific deoxyribonuclease activity

description: Any process that modulates the frequency, rate or extent of a type I restriction endodeoxyribonuclease activity.


cellular response to iron(III) ion

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron(III) ion stimulus.


name: platelet-activating factor acetyltransferase activity

description: Catalysis of the reaction: 1-radyl-2-acyl-sn-glycero-3-phospholipid + 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine = 1-alkyl-2-lyso-sn-glycero-3-phosphocholine + 1-radyl-2-acetyl-sn-glycero-3-phospholipid.


tRNA (guanine-N7)-methylation

description: The process whereby a guanine in a tRNA is methylated at the N7 position of guanine.


sequestering of copper ion

description: The process of binding or confining copper ions such that they are separated from other components of a biological system.


name: pentose transmembrane transporter activity

description: Enables the transfer of a pentose sugar from one side of a membrane to the other. Pentose is a monosaccharide with 5 carbon atoms.


name: positive regulation of mechanosensory behavior

description: Any process that activates or increases the frequency, rate or extent of mechanosensory behavior.


name: urinary bladder smooth muscle contraction

description: A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the urinary bladder. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The urinary bladder is a musculomembranous sac along the urinary tract.


flavonol binding

description: Binding to a flavonol, a flavonoid that contains a 3-hydroxy-2-phenylchromen-4-one backbone.


name: positive regulation of apoptotic process involved in metanephric nephron tubule development

description: Any process that activates or increases the frequency, rate or extent of apoptotic process involved in metanephric nephron tubule development.


name: delphinidin 3-O-rutinoside 7-O-glucosyltransferase (acyl-glucose dependent) activity

description: Catalysis of the reaction: delphinidin 3-O-rutinoside + 1-O-4-hydroxybenzoyl-beta-D-glucose = delphinidin 3-O-rutinoside-7-O-glucoside + 4-hydroxybenzoic acid + H+.


description: Catalysis of the reaction: hydroxymalonate + sinapoyl-CoA = CoA + sinapoyltartronate.


acquisition of desiccation tolerance

description: The process in which tolerance to severe drying is acquired, before entering into a dry, either dormant or quiescent state.


name: D-xylose 1-dehydrogenase (NAD+) activity

description: Catalysis of the reaction: D-xylose + NAD+ = D-xylonolactone + NADH.


regulation of NK T cell activation

description: Any process that modulates the frequency, rate or extent of natural killer T cell activation.


name: methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity

description: Catalysis of the reaction: 5,10-methylenetetrahydrofolate + NAD(P)+ = 5,10-methenyltetrahydrofolate + NAD(P)H + H+.


name: UDP-glucose:curcumin monoglucoside glucosyltransferase activity

description: Catalysis of the reaction: UDP-alpha-D-glucose + curcumin monoglucoside = H+ + curcumin diglucoside + UDP.


name: positive regulation of endothelial tube morphogenesis

description: Any process that activates or increases the frequency, rate or extent of endothelial tube morphogenesis.


name: establishment or maintenance of cell polarity regulating cell shape

description: Any cellular process that results in the specification, formation or maintenance of a polarized intracellular organization or cell growth patterns that regulate the shape of a cell.


name: acetylcholine catabolic process in synaptic cleft

description: The chemical reactions and pathways resulting in the breakdown of acetylcholine that occurs in the synaptic cleft during synaptic transmission.


positive regulation of serotonin uptake

description: Any process that activates or increases the frequency, rate or extent of the directed movement of serotonin into a cell.


bract morphogenesis

description: The process in which the anatomical structure of a bract are generated and organized. A bract is a leaf, usually different in form from the foliage leaves, subtending a flower or inflorescence.


sepal formation

description: The process that gives rise to the sepal. This process pertains to the initial formation of a structure from unspecified parts.


embryo implantation

description: Attachment of the blastocyst to the uterine lining.


muramyl dipeptide kinase activity

description: Catalysis of the reaction: ATP + muramyl dipeptide = ADP + H+ + 6-O-phospho-muramyl dipeptide.


name: ferric-enterobactin transmembrane transporter activity

description: Enables the transfer of ferric-enterobactin from one side of a membrane to the other.


name: positive regulation of cellular pH reduction

description: Any process that activates or increases the frequency, rate, or extent of a process that reduces the internal pH of a cell.


description: Catalysis of the reaction: 1-carboxyvinyl carboxyphosphonate = 3-(hydrohydroxyphosphoryl)pyruvate + CO2.


leg disc development

description: Progression of the leg imaginal disc over time, from its initial formation through to its metamorphosis to form adult structures including the leg, coxa and ventral thoracic pleura.


description: Catalysis of the reaction: acetyl-CoA + aminoglycoside = CoA + N-acetylaminoglycoside.


name: positive regulation of B cell proliferation

description: Any process that activates or increases the rate or extent of B cell proliferation.


name: specification of proximal tubule identity

description: The process in which the proximal tubule of the kidney nephron acquires its identity.


clearance of cells from fusion plate

description: The morphogenetic process in which cells are removed from the inner loop of a semicircular canal.


name: negative regulation of outer hair cell apoptotic process

description: Any process that stops, prevents or reduces the frequency, rate or extent of outer hair cell apoptotic process.


name: nitronate monooxygenase (FMN-linked) activity

description: Catalysis of the reaction: ethylnitronate + FMNH(2) + O2 = acetaldehyde + FMN + H2O + H+ + nitrite.


morphogenesis of a branching epithelium

description: The process in which the anatomical structures of a branched epithelium are generated and organized.


polyprenol metabolic process

description: The chemical reactions and pathways involving polyprenols, prenols with more than 4 isoprenoid residues, which may be all-trans, or a mixture of cis and trans.


response to ATP

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ATP (adenosine 5'-triphosphate) stimulus.


negative regulation of bone resorption

description: Any process that stops, prevents, or reduces the frequency, rate or extent of bone resorption.


description: Catalysis of the reaction: procollagen L-proline + 2-oxoglutarate + O2 = procollagen trans-hydroxy-L-proline + succinate + CO2.


peroxidase activity

description: Catalysis of the reaction: a donor + a peroxide = an oxidized donor + 2 H2O.


name: symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity

description: A process in which a symbiont interferes with, inhibits or disrupts a cytoplasmic pattern recognition receptor signaling pathway in a host organism by reducing the activity of host IRF3 (interferon regulatory factor-3). IRF3 is a transcription factor in the RIG-I/MDA-5 signaling pathway. Viral infection triggers phosphorylation of cytoplasmic IRF3, which allows IRF3 to form a homodimer, migrate to the nucleus, and activate transcription of IFN-alpha and IFN-beta genes.


description: Catalysis of the reaction:H2O + N(6)-propanoyl-L-lysyl-[protein] + NAD+ = 3''-O-propanoyl-ADP-D-ribose + L-lysyl-[protein] + nicotinamide.


nitric-oxide synthase activity

description: Catalysis of the reaction: L-arginine + n NADPH + n H+ + m O2 = citrulline + nitric oxide + n NADP+.


name: oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water

description: Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from each of two donors, and molecular oxygen is reduced to two molecules of water.


response to high light intensity

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a high light intensity stimulus.


name: 5-(carboxyamino)imidazole ribonucleotide synthase activity

description: Catalysis of the reaction: 5-amino-1-(5-phospho-D-ribosyl)imidazole + ATP + bicarbonate = 5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole + ADP + 3 H+ + phosphate.


description: Catalysis of the reaction: a 3-beta-hydroxysterol + triacylglycerol = a 3-beta-hydroxysterol ester + 1,2-diacylglycerol.


description: Catalysis of the reaction: ATP + 3-dephospho-CoA = 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA + adenine.


motor neuron migration

description: The orderly movement of a motor neuron from one site to another. A motor neuron is an efferent neuron that passes from the central nervous system or a ganglion toward or to a muscle and conducts an impulse that causes movement.


phenanthrene catabolic process

description: The chemical reactions and pathways resulting in the breakdown of phenanthrene, a tricyclic aromatic hydrocarbon.


description: Catalysis of the reaction: taurine + 2-oxoglutarate = sulfoacetaldehyde + L-glutamate.


TMP metabolic process

description: The chemical reactions and pathways involving TMP, ribosylthymine monophosphate.


description: Catalysis of the reaction: a long-chain aldehyde + NAD+ = a long-chain carboxylate + NADH + H+. A long-chain aldehyde is one with more than 12 carbons.


name: very-long-chain 3-oxoacyl-CoA reductase activity

description: Catalysis of the reaction: a very-long-chain (3R)-3-hydroxyacyl-CoA + NADP+ = a very-long-chain 3-oxoacyl-CoA + H+ + NADPH. This reaction is the second (reduction) step of the four-step fatty acid elongation cycle in the endoplasmic reticulum that extends fatty acids of C-16 or longer with an additional 2-C unit.


name: metanephric proximal convoluted tubule development

description: The process whose specific outcome is the progression of the metanephric proximal convoluted tubule over time, from its formation to the mature structure. The metanephric proximal convoluted tubule is the most proximal portion of the metanephric proximal tubule and extends from the metanephric glomerular capsule to the metanephric proximal straight tubule.


carnitine biosynthetic process

description: The chemical reactions and pathways resulting in the formation of carnitine (hydroxy-trimethyl aminobutyric acid), a compound that participates in the transfer of acyl groups across the inner mitochondrial membrane.


name: positive regulation of meiotic cell cycle process involved in oocyte maturation

description: Any process that activates or increases the frequency, rate or extent of meiotic cell cycle process involved in oocyte maturation.


name: proximal/distal pattern formation, imaginal disc

description: The establishment, maintenance and elaboration of the proximal/distal axis of the imaginal disc. Imaginal disks are masses of hypodermic cells, carried by the larvae of some insects after leaving the egg, from which masses the wings and legs of the adult are subsequently formed.


questin monooxygenase activity

description: Catalysis of the reaction: H+ + NADPH + O2 + questin = demethylsulochrin + NADP+.


name: glycine betaine biosynthetic process from choline

description: The chemical reactions and pathways resulting in the formation of betaine (N-trimethylglycine) from the oxidation of choline.


senecionine N-oxygenase activity

description: Catalysis of the reaction: H+ + NADPH + O2 + senecionine = H2O + NADP+ + senecionine N-oxide.


name: regulation of hepatic stellate cell contraction

description: Any process that modulates the frequency, rate or extent of hepatic stellate cell contraction.


cellular detoxification of sulfide

description: Any process carried out at the cellular level that reduces or removes the toxicity of a sulfide. These may include chemical modification or transport of sulfide away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance.


name: positive regulation of substrate adhesion-dependent cell spreading

description: Any process that activates or increases the frequency, rate or extent of substrate adhesion-dependent cell spreading.


prostaglandin D receptor activity

description: Combining with prostaglandin D (PGD(2)) to initiate a change in cell activity.


name: regulation of vasoconstriction by neuronal epinephrine

description: Any process that modulates the frequency, rate or extent of reductions in the diameter of blood vessels as a result of epinephrine released by nerve endings.


oxaloacetase activity

description: Catalysis of the reaction: H2O + oxaloacetate = acetate + H+ + oxalate.


name: positive regulation of secondary heart field cardioblast proliferation

description: Any process that activates or increases the frequency, rate or extent of cardioblast proliferation in the second heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating. The secondary heart field is the region of the heart that will form the majority of the mesodermal component of the right ventricle, the arterial pole (outflow tract) and the venous pole (inflow tract).


peptidyl-glutamate ADP-deribosylation

description: The removal of ADP-ribose from ADP-ribosylglutamate.


name: positive regulation of steroid metabolic process

description: Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving steroids.


N-terminal peptidyl-leucine methylation

description: The methylation of the N-terminal leucine of proteins to form the derivative N-methyl-L-leucine.


name: alkane transmembrane transporter activity

description: Enables the transfer of alkanes from one side of a membrane to the other. Alkanes are saturated aliphatic hydrocarbon compounds.


name: positive regulation of smooth muscle cell-matrix adhesion

description: Any process that activates or increases the frequency, rate or extent of smooth muscle cell-matrix adhesion.


peptidyl-cysteine phosphorylation

description: The phosphorylation of peptidyl-cysteine to form peptidyl-S-phospho-L-cysteine.


virion attachment to host cell

description: The process by which a virion protein binds to molecules on the host cellular surface or host cell surface projection.


name: mesonephric smooth muscle tissue development

description: The process whose specific outcome is the progression of smooth muscle in the mesonephros over time, from its formation to the mature structure.


name: oxidoreductase activity, acting on metal ions, NAD or NADP as acceptor

description: Catalysis of an oxidation-reduction in which the metal ion is reduced and NAD+ or NADP+ acts as an electron acceptor.


tricellular tight junction disassembly

description: The disaggregation of a tricellular tight junction into its constituent components.


description: Catalysis of the reaction: 2-amino-3-carboxymuconate 6-semialdehyde + H+ = 2-aminomuconate 6-semialdehyde + CO2.


name: regulation of vascular permeability involved in acute inflammatory response

description: Any process that modulates the extent to which blood vessels can be pervaded by fluid contributing to an acute inflammatory response.


name: regulation of cell-cell adhesion mediated by integrin

description: Any process that modulates the frequency, rate, or extent of cell-cell adhesion mediated by integrin.


glycerophosphate shuttle

description: The process of transferring reducing equivalents from the cytosol into the mitochondria; NADH is used to synthesise glycerol 3-phosphate in the cytosol; this compound is then transported into the mitochondria where it is converted to dihydroxyacetone phosphate (DHAP) using FAD; DHAP then returns to the cytosol to complete the cycle.


beta-galactofuranosidase activity

description: Catalysis of the hydrolysis of terminal non-reducing beta-D-galactofuranosides, releasing galactose.


isofucosterol hydroxylase activity

description: Catalysis of the reaction: H+ + isofucosterol + O2 + NADPH = (22alpha)-hydroxy-isofucosterol + H2O + NADP.


description: Catalysis of the reaction: 3-(all-trans-octaprenyl)benzene-1,2-diol + S-adenosyl-L-methionine = H+ + 2-methoxy-6-(all-trans-octaprenyl)phenol + S-adenosyl-L-homocysteine.


heparanase activity

description: Catalysis of the cleavage of heparan sulfate; can degrade both heparan sulfate and heparin glycosaminoglycan chains.


delta-carotene metabolic process

description: The chemical reactions and pathways involving delta-carotene.


description: Catalysis of the reaction: ATP + hygromycin B = 7''-O-phosphohygromycin B + ADP + 2 H+.


demethoxycurcumin synthase

description: Catalysis of the reaction: (4-coumaroyl)acetyl-CoA + 4-coumaryl-CoA + H2O = bisdemethoxycurcumin + 2 coenzyme A + carbon dioxide.


name: protein-N6-(L-lysyl)-L-lysine modification to protein-N6-(beta-lysyl)-L-lysine

description: The modification of an N6-(lysyl)-L-lysine residue in a protein, producing protein-N6-(beta-lysyl)-L-lysine ((2S)-2-amino-6-([(2S)-2,6-diaminohexanoyl]amino)hexanoic acid). This modification is observed in, and is probably unique to, translation elongation factor P (EF-P).


response to acidic pH

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus with pH < 7. pH is a measure of the acidity or basicity of an aqueous solution.


carotenoid catabolic process

description: The chemical reactions and pathways resulting in the breakdown of carotenoids, tetraterpenoid compounds in which two units of 4 isoprenoid residues joined head-to-tail are themselves joined tail-to-tail.


diacylglycerol biosynthetic process

description: The chemical reactions and pathways resulting in the formation of diacylglycerol, a glyceride in which any two of the R groups (positions not specified) are acyl groups while the remaining R group can be either H or an alkyl group.


name: hexuronate:monoatomic cation symporter activity

description: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: hexuronate(out) + cation(out) = hexuronate(in) + cation(in). The hexuronate may be glucuronate or galacturonate.


name: regulation of adaptive immune effector response

description: Any process that modulates the frequency, rate or extent of adaptive immune effector response.


cholate 7-alpha-dehydrogenase activity

description: Catalysis of the reaction: cholate + NAD+ = 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanate + H+ + NADH.


peripheral T cell tolerance induction

description: Tolerance induction of T cells in the periphery, in this case, any location in the body other than the thymus.


name: dihydroorotate dehydrogenase (NADP+) activity

description: Catalysis of the reaction: (S)-dihydroorotate + NADP+ = H+ + NADPH + orotate.


name: chemokine (C-C motif) ligand 19 production

description: The appearance of chemokine (C-C motif) ligand 19 (CCL19) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


description: The chemical reactions and pathways involving glyceraldehyde-3-phosphate, an important intermediate in glycolysis.


xylitol kinase activity

description: Catalysis of the reaction: ATP + xylitol = ADP + 2 H+ + xylitol 5-phosphate.


name: gibberellin A20,2-oxoglutarate:oxygen oxidoreductase activity

description: Catalysis of the reaction: gibberellin A20 + 2-oxoglutarate + O2 = gibberellin A29 + succinate + carbon dioxide.


name: telomerase RNA localization to Cajal body

description: A process in which telomerase RNA (TERC) is transported to, or maintained in, a Cajal body.


name: clathrin coating of Golgi vesicle, plasma membrane to endosome targeting

description: The addition of clathrin and adaptor proteins to Golgi membranes during the formation of transport vesicles that will move from the plasma membrane to the endosome, forming a vesicle coat.


lactone catabolic process

description: The chemical reactions and pathways resulting in the breakdown of lactone.


flurbiprofen binding

description: Binding to flurbiprofen.


name: ATP-dependent H3-H4 histone complex chaperone activity

description: A histone chaperone that carries a H3-H4 histone complex, driven by ATP hydrolysis.


interferon receptor activity

description: Combining with an interferon and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


name: regulation of retrograde transport, endosome to Golgi

description: Any process that modulates the frequency, rate or extent of retrograde transport, endosome to Golgi.


name: regulation of branching involved in lung morphogenesis

description: Any process that modulates the rate, frequency, or extent of the process in which a highly ordered sequence of patterning events generates the branched structures of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units.


ERBB4-ERBB4 signaling pathway

description: The series of molecular signals initiated by binding of a ligand to the tyrosine kinase receptor ERBB4, followed by ligand-induced homodimerization of ERBB4 and transmission of the signal into the cell by the homodimeric ERBB4 complex. The pathway ends with regulation of a downstream cellular process, e.g. transcription.


protein guanylyltransferase activity

description: Catalysis of the reaction: GTP + protein = diphosphate + guanylyl-protein; mediates the addition of an guanylyl (guanosine 5'-monophosphate; GMP group) to specific residues of target proteins.


name: regulation of mast cell apoptotic process

description: Any process that modulates the frequency, rate, or extent of mast cell apoptotic process.


adipokinetic hormone receptor activity

description: Combining with an adipokinetic hormone to initiate a change in cell activity. Adipokinetic hormones (AKHs) are protein or peptide hormones that are important for sugar and fat homeostasis in metazoa. In insects, they mobilize sugar and lipids from the insect fat body during energy-requiring activities such as flight and locomotion. They also contribute to hemolymph sugar homeostasis.


name: Notch signaling pathway involved in negative regulation of venous endothelial cell fate commitment

description: Any Notch signaling pathway that is involved in negative regulation of venous endothelial cell fate commitment.


cardiac muscle cell fate determination

description: The process involved in cardiac muscle cell fate commitment. Once determination has taken place, a cell becomes committed to differentiate down a particular pathway regardless of its environment.


name: spinal cord motor neuron cell fate specification

description: The process in which a cell becomes capable of differentiating autonomously into a motor neuron in an environment that is neutral with respect to the developmental pathway.


name: extracellularly glutamate-gated ion channel activity

description: Enables the transmembrane transfer of an ion by a channel that opens when glutamate is bound by the channel complex or one of its constituent parts on the extracellular side of the plasma membrane.


name: beta-L-Ara4N-lipid A biosynthetic process

description: The chemical reactions and pathways resulting in the formation of beta-L-Ara4N-lipid A which occurs as a result of modification of the lipid A moiety of lipopolysaccharide by the addition of the sugar 4-amino-4-deoxy-L-arabinose (L-Ara4N). This strategy is adopted by pathogenic Gram-negative bacteria to evade cationic antimicrobial peptides produced by the innate immune system.


T-helper 1 cell lineage commitment

description: The process in which a CD4-positive, alpha-beta T cell becomes committed to becoming a T-helper 1 cell, a CD4-positive, alpha-beta T cell specialized to promote immunological processes often associated with resistance to intracellular bacteria, fungi, and protozoa, and pathological conditions such as arthritis.


name: negative regulation of the force of heart contraction involved in baroreceptor response to increased systemic arterial blood pressure

description: Any process that decreases the force with which the cardiac muscles of the heart pump blood through the circulatory system as a result of the baroreceptor response to increased blood pressure.


description: The chemical reactions and pathways resulting in the formation of O3-(phosphoglycosyl-D-mannose-1-phosphoryl)-L-serine. The polypeptide backbones of glycoproteins and mucin-like proteoglycans are extensively modified with a complex array of phosphoglycan chains that are linked to Ser/Thr-rich domains via a common Man-alpha1-phosphate-Ser linkage.


name: positive regulation of adult salivary gland boundary specification

description: Any process that activates or increases the frequency, rate or extent of salivary gland determination in an adult organism.


polysaccharide immune receptor activity

description: Combining with a polysaccharide and transmitting the signal to initiate an innate immune response. A polysaccharide is a polymer of many (typically more than 10) monosaccharide residues linked glycosidically.


name: in-chain hydroxy fatty acyl-CoA synthetase activity

description: Catalysis of the reaction: coenzyme A + ATP + an in-chain hydroxy fatty acid = diphosphoric acid + AMP + a in-chain hydroxyacyl-CoA.


zymosterol metabolic process

description: The chemical reactions and pathways involving zymosterol, (5alpha-cholesta-8,24-dien-3beta-ol).


regulation of estrogen secretion

description: Any process that modulates the frequency, rate or extent of estrogen secretion.


name: regulation of juvenile hormone secretion

description: Any process that modulates the frequency, rate or extent of juvenile hormone secretion.


cysteine desulfurase activity

description: Catalysis of the reaction: L-cysteine + [enzyme]-cysteine = L-alanine + [enzyme]-S-sulfanylcysteine.


regulation of eosinophil activation

description: Any process that modulates the frequency, rate or extent of eosinophil activation.


regulation of heart rate by hormone

description: The process in which the hormones modulates the rate of heart muscle contraction. A hormone is one of a group of substances formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells, in the same organism, upon which they have a specific regulatory action.


T-helper 17 cell chemotaxis

description: The directed movement of a T-helper 17 cell in response to an external stimulus.


name: negative regulation of leukocyte proliferation

description: Any process that stops, prevents, or reduces the frequency, rate or extent of leukocyte proliferation.


eosinophil mediated immunity

description: Any process involved in the carrying out of an immune response by an eosinophil.


name: regulation of xanthophore differentiation

description: Any process that modulates the frequency, rate or extent of xanthophore differentiation.


name: negative regulation of blood vessel remodeling

description: Any process that decreases the rate, frequency or extent of blood vessel remodeling, the reorganization or renovation of existing blood vessels.


name: epidermis morphogenesis involved in nipple formation

description: The process in which the epidermis of the nipple sheath is uplifted to form an umbrella-like projection.


name: modulation by host of viral transcription

description: Any process in which a host organism modulates the frequency, rate or extent of viral transcription.


aldehyde dehydrogenase (NAD+) activity

description: Catalysis of the reaction: an aldehyde + H2O + NAD+ = a carboxylate + 2 H+ + NADH.


inositol phosphate biosynthetic process

description: The chemical reactions and pathways resulting in the formation of an inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with one or more phosphate groups attached.


naringenin-chalcone synthase activity

description: Catalysis of the reaction: 3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO2.


alpha-copaene metabolic process

description: The chemical reactions and pathways involving alpha-copaene.


hydrogen sulfide metabolic process

description: The chemical reactions and pathways involving hydrogen sulfide, H2S.


intracellular nitrogen homeostasis

description: A homeostatic process involved in the maintenance of a steady state level of nitrogen within a cell.


meiotic telophase II

description: The cell cycle phase which follows anaphase II of meiosis and during which the chromosomes arrive at the poles of the cell and the division of the cytoplasm starts.


cephamycin C metabolic process

description: The chemical reactions and pathways involving cephamycin C.


name: voltage-gated calcium channel activity involved in regulation of cytosolic calcium levels

description: Regulation of cytosolic calcium ion concentrations via the directed movement of calcium ions across the plasma-membrane into the cytosol via the action of a voltage-gated calcium ion channel.


exit from dormancy

description: The dormancy process that results in exit from dormancy. Dormancy (sometimes called a dormant state) is a suspension of most physiological activity and growth that can be reactivated.


name: methyl transfer-driven active transmembrane transporter activity

description: Primary active transport of a solute across a membrane driven by a methyl transfer reaction. Primary active transport is catalysis of the transport of a solute across a membrane, up the solute's concentration gradient, by binding the solute and undergoing a series of conformational changes. Transport works equally well in either direction and is driven by a primary energy source.


respiratory chain complex III assembly

description: The aggregation, arrangement and bonding together of a set of components to form the cytochrome bc(1) complex, a transmembrane lipoprotein complex that it catalyzes the reduction of cytochrome c by accepting reducing equivalents from Coenzyme Q, by the aggregation, arrangement and bonding together of its constituents.


name: regulation of paraxial mesodermal cell fate determination

description: Any process that modulates the frequency, rate or extent of paraxial mesoderm cell fate determination.


nitroimidazole catabolic process

description: The chemical reactions and pathways resulting in the breakdown of nitroimidazoles, imidazole derivatives with a nitro group attached to one ring.


regulation of premature acrosome loss

description: Any process that modulates the rate, frequency or extent of the discharge, by sperm, of a single, anterior secretory granule before the sperm reaches to the zona pellucida of the oocyte. The process begins with the fusion of the outer acrosomal membrane with the sperm plasma membrane and ends with the exocytosis of the acrosomal contents.


name: central nervous system neuron axonogenesis

description: Generation of a long process from a neuron whose cell body resides in the central nervous system. The process carries efferent (outgoing) action potentials from the cell body towards target cells.


description: Catalysis of the reaction: 5-(carboxymethyl)uridine34 in tRNA + S-adenosyl-L-methionine = 5-(2-methoxy-2-oxoethyl)uridine34 in tRNA + S-adenosyl-L-homocysteine.


name: negative regulation of transmembrane transport

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a solute from one side of a membrane to the other.


name: negative regulation of monoatomic anion transport

description: Any process that stops, prevents or reduces the frequency, rate or extent of anion transport.


cuprous ion binding

description: Binding to a cuprous ion, copper(1+).


name: negative regulation of nuclear migration during mitotic telophase

description: Any process that stops, prevents or reduces the frequency, rate or extent of nuclear migration during mitotic telophase.


name: regulation of octopamine signaling pathway involved in response to food

description: Any process that modulates the frequency, rate or extent of octopamine signaling pathway involved in response to food.


description: Catalysis of the reaction: 5,10-methylenetetrahydrofolate + glycine + H2O = tetrahydrofolate + L-serine.


description: Catalysis of the transfer of an arachidonoyl (systematic name, (5Z,8Z,11Z,14Z)-eicosatetraenoyl) group to a sulfur atom on the cysteine of a protein molecule, in the reaction: in the reaction: (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + L-cysteinyl-[protein] = CoA + S-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-L-cysteinyl-[protein].


helvolic acid metabolic process

description: The chemical reactions and pathways involving helvolic acid.


name: envenomation resulting in negative regulation of sensory perception of pain in another organism

description: A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the inhibition of the sensory perception of pain in the bitten organism.


resolvin biosynthetic process

description: The chemical reactions and pathways resulting in the formation of resolvins, di- or trihydroxy fatty acids derived from omega-3 polyunsaturated fatty acids, specifically icosapentaenoic acid, docosahexaenoic acid and docosapentaenoic acid.


name: positive regulation of long-chain fatty acid import across plasma membrane

description: Any process that increases the rate, frequency or extent of plasma membrane long-chain fatty acid transport. Plasma membrane long-chain fatty acid transport is the directed movement of long-chain fatty acids across the plasma membrane. A long-chain fatty acid has an aliphatic tail containing 13 to 22 carbons.


name: positive regulation of hindgut contraction

description: Any process that increases the frequency, rate or extent of muscle contraction of the hindgut, the posterior part of the alimentary canal, including the rectum, and the large intestine.


name: 20-aldehyde-leukotriene B4 20-monooxygenase activity

description: Catalysis of the reaction: 20-oxo-leukotriene B4 + O2 + reduced [NADPH-hemoprotein reductase] = 20-carboxy-leukotriene B4 + 2 H+ + H2O + oxidized [NADPH-hemoprotein reductase].


peptide modification

description: The covalent alteration of one or more amino acid residues within a peptide, resulting in a change in the properties of that peptide.


aortic valve formation

description: The developmental process pertaining to the initial formation of the aortic valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable.


detection of hypoxia

description: The series of events in which a stimulus indicating lowered oxygen tension is received by a cell and converted into a molecular signal. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.


nitrite reductase (NO-forming) activity

description: Catalysis of the reaction: nitric oxide + H2O + ferricytochrome c = nitrite + ferrocytochrome c + 2 H+.


comma-shaped body morphogenesis

description: The process in which the comma-shaped body is generated and organized. The comma-shaped body is the precursor structure to the S-shaped body that contributes to the morphogenesis of the nephron.


description: Catalysis of the reaction: a 10-formyltetrahydrofolate-4a-carbinolamine = H2O + a 10-formyldihydrofolate.


name: cell-cell adhesion involved in neural tube closure

description: The attachment of one cell to another cell along the edges of two epithelial folds, giving rise to the lumen of the neural tube.


name: maintenance of vegetative meristem identity

description: The process in which an organism retains a population of vegetative meristem cells, preventing the commitment of all stem cell progeny to a differentiated cell fate.


glycolytic fermentation to butanediol

description: The anaerobic chemical reactions and pathways resulting in the breakdown of glucose into butanediol; effected by some members of the Enterobacteriaceae, e.g. Enterobacter, Erwinia, Klebsiella, and Serratia.


G2 phase

description: The cell cycle 'gap' phase which is the interval between the completion of DNA synthesis and the beginning of DNA segregation (usually by mitosis or meiosis).


description: Catalysis of the reaction: S-adenosyl-L-methionine + DNA containing cytosine = S-adenosyl-L-homocysteine + DNA containing 5-methylcytosine.


protein polyglutamylation

description: The addition of one or more alpha-linked glutamyl units to the gamma carboxyl group of peptidyl-glutamic acid.


myeloid cell homeostasis

description: The process of regulating the proliferation and elimination of myeloid cells such that the total number of myeloid cells within a whole or part of an organism is stable over time in the absence of an outside stimulus.


description: The series of molecular signals initiated by interleukin-19 binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.


name: growth plate cartilage chondrocyte development

description: The progression of a growth plate cartilage chondrocyte over time from after its fate commitment to the mature cell.


visceral peritoneum development

description: The process whose specific outcome is the progression of a visceral peritoneum over time, from its formation to the mature structure.


membrane raft organization

description: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of membrane rafts, small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes.


detection of cAMP

description: The series of events in which a cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate) stimulus is received by a cell and converted into a molecular signal; cAMP is the nucleotide cyclic AMP.


name: histone H3R17 arginine deiminase activity

description: Catalysis of the reaction: H2O + histone H3 L-arginyl (position 17)= histone H3 L-citrullyl (position 17) + NH4+, resulting in histone H3 citrullination at position 17.


L-fucose catabolic process

description: The chemical reactions and pathways resulting in the breakdown of L-fucose (6-deoxy-Lgalactose).


phosphatidylglycerol binding

description: Binding to phosphatidylglycerol.


name: muscle cell chemotaxis toward tendon cell

description: The directed movement of a muscle cell towards a tendon cell in response to an external stimulus. Tendon cells, for example, produce positive guidance cues that attract muscle cells.


regulation of endoribonuclease activity

description: Any process that modulates the rate, frequency or extent of the catalysis of the hydrolysis of ester linkages within ribonucleic acid by creating internal breaks.


name: protein maturation by iron-sulfur cluster transfer

description: The transfer of an assembled iron-sulfur cluster from a scaffold protein to an acceptor protein that contributes to the attainment of the full functional capacity of a protein.


name: double-strand break repair via synthesis-dependent strand annealing

description: SDSA is a major mechanism of double-strand break repair in mitosis which allows for the error-free repair of a double-strand break without the exchange of adjacent sequences. The broken DNA searches for and base pairs with a homologous region in an intact chromosome. DNA synthesis initiates from the 3' end of the invading DNA strand, using the intact chromosome as the template. Newly synthesized DNA is then displaced from the template and anneal with its complement on the other side of the double-strand break.


description: Catalysis of the reaction: L-histidyl-[protein] + S-adenosyl-L-methionine = N(pros)-methyl-L-histidyl-[protein] + S-adenosyl-L-homocysteine.


O6-methyl-dGTP hydrolase activity

description: Catalysis of the reaction O6-methyl-dGTP + H2O = O6-methyl-dGMP + diphosphate + H+.


description: The series of molecular signals initiated by interleukin-8 binding to its receptor on the surface of a cell, and ending with the regulation of a downstream cellular process, e.g. transcription.


name: sporocarp development involved in sexual reproduction

description: The process whose specific outcome is the progression of a fruiting body organ over time, from its formation to the mature structure. The fruiting body is a spore bearing structure. In fungi, the sporocarp (also known as fruiting body) is a multicellular structure on which spore-producing structures, such as basidia or asci, are borne. The fruiting body is part of the sexual phase of a fungal life cycle, with the rest of the life cycle being characterized by vegetative mycelial growth. The sporocarp of a basidiomycete is known as a basidiocarp, while the fruiting body of an ascomycete is known as an ascocarp. A significant range of different shapes and morphologies is found in both basidiocarps and ascocarps; these features play an important role in the identification and taxonomy of fungi.


regulation of defecation

description: Any process that modulates the frequency, rate or extent of defecation.


dGMP biosynthetic process

description: The chemical reactions and pathways resulting in the formation of dGMP, deoxyguanosine monophosphate (2'-deoxyguanosine 5'-phosphate).


regulation of chloride transport

description: Any process that modulates the frequency, rate or extent of chloride transport.


name: positive regulation of eosinophil differentiation

description: Any process that activates or increases the frequency, rate or extent of eosinophil differentiation.


name: termination of RNA polymerase II transcription, exosome-dependent

description: The process in which transcription of nonpolyadenylated RNA polymerase II transcripts is terminated; coupled to the maturation of the RNA 3'-end.


description: Catalysis of the reaction: S-adenosyl-L-methionine + guanine(37) in tRNA = N(1)-methylguanine(37) in tRNA + S-adenosyl-L-homocysteine.


name: regulation by virus of viral protein levels in host cell

description: Any virus-mediated process that modulates the levels of viral proteins in a cell.


name: intracellular sequestering of copper ion

description: The process of binding or confining copper ions in an intracellular area such that they are separated from other components of a biological system.


name: cell-cell signaling involved in pronephros development

description: Any process that mediates the transfer of information from one cell to another and contributes to the progression of the pronephros over time, from its formation to the mature organ.


regulation of cell fate specification

description: Any process that mediates the adoption of a specific fate by a cell.


regulation of membrane permeability

description: Any process that modulates the frequency, rate or extent of the passage or uptake of molecules by a membrane.


Schwann cell proliferation

description: The multiplication or reproduction of Schwann cells, resulting in the expansion of their population. Schwann cells are a type of glial cell in the peripheral nervous system.


name: regulation of cellobiose catabolic process

description: Any process that modulates the frequency, rate or extent of cellobiose catabolic process.


tagaturonate reductase activity

description: Catalysis of the reaction: D-altronate + NAD+ = D-tagaturonate + H+ + NADH.


name: positive regulation of DNA strand resection involved in replication fork processing

description: Any process that activates or increases the frequency, rate or extent of DNA strand resection involved in replication fork processing.


description: Catalysis of the reaction: 1,1-dichloro-2,2-bis(4-chlorophenyl)ethane = HCl + 1-chloro-2,2-bis(4-chlorophenyl)ethene. 1,1-dichloro-2,2-bis(4-chlorophenyl)ethane is also known as DDD; 1-chloro-2,2-bis(4-chlorophenyl)ethene is also known as DDMU.


11-cis-retinal 3,4-desaturase activity

description: Catalysis of the reaction: 11-cis-retinal + 2 H+ + O2 + 2 reduced [adrenodoxin] = 11-cis-3,4-didehydro-retinal + 2 H2O + 2 oxidized [adrenodoxin].


name: regulation of methanophenazine metabolic process

description: Any process that modulates the frequency, rate or extent of methanophenazine metabolic process.


stomatal complex patterning

description: The regionalization process of establishing the non-random spatial arrangement of stomatal complex on the surface of a leaf. The stomatal complex is the stomatal guard cells and their associated epidermal cells.


n-octane metabolic process

description: The chemical reactions and pathways involving n-octane, the 8 carbon straight chain alkane used in organic syntheses, calibrations, and azeotropic distillations. It is a common component of gasoline and other petroleum products and the engine fuel antiknocking properties of an isomer of n-octane are used as a comparative standard in the Octane Rating System.


tRNA folding

description: The process of assisting in the folding of tRNAs into the correct tertiary structure.


lncRNA binding

description: Binding to a long noncoding RNA (lncRNA).


astrocyte cell migration

description: The orderly movement of an astrocyte, a class of large neuroglial (macroglial) cells in the central nervous system, the largest and most numerous neuroglial cells in the brain and spinal cord.


name: cellular response to stem cell factor stimulus

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stem cell factor (SCF) stimulus.


name: D-malate dehydrogenase (decarboxylating) activity

description: Catalysis of the reaction: (R)-malate + NAD+ = CO2 + NADH + pyruvate.


calcitonin receptor activity

description: Combining with calcitonin and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.


name: regulation of angiotensin levels in blood

description: The process that modulates the level of any of the various angiotensinogen proteolytic products in the blood. This occurs by the proteolytic cleavage of angiotensinogen, and its proteolytic products, to create a variety of active peptide hormones, such as angiotensin I and angiotensin II, as well as through the removal of these peptides from the circulation.


cardiac ventricle formation

description: The developmental process pertaining to the initial formation of a cardiac ventricle from unspecified parts. A cardiac ventricle receives blood from a cardiac atrium and pumps it out of the heart.


name: tetralin ring-hydroxylating dioxygenase activity

description: Catalysis of the reaction: tetralin + O2 + NADH + H+ = cis-1,2-dihydroxy-1,2,5,6,7,8-hexahydronaphthalene + NAD+.


name: symbiont-mediated perturbation of host innate immune response

description: A process in which a symbiont alters or subverts the innate immune response of the host organism; the innate immune response is the host's first line of defense against infection. The host is defined as the larger of the organisms involved in a symbiotic interaction.


name: intracellularly ligand-gated monoatomic ion channel activity

description: Enables the transmembrane transfer of an ion by a channel that opens when a specific intracellular ligand has been bound by the channel complex or one of its constituent parts.


mitochondrial tRNA methylation

description: The posttranscriptional addition of methyl groups to specific residues in a mitochondrial tRNA molecule.


regulation of animal organ formation

description: Any process that modulates the rate, frequency or extent of animal organ formation. Organ formation is the process pertaining to the initial formation of an organ from unspecified parts. The process begins with the specific processes that contribute to the appearance of the discrete structure, such as inductive events, and ends when the structural rudiment of the organ is recognizable, such as a condensation of mesenchymal cells into the organ rudiment.


modulation of spore encystment on host

description: Any process that modulates the frequency, rate or extent of spore encystment on host. The host is defined as the larger of the organisms involved in a symbiotic interaction.


glutamate catabolic process

description: The chemical reactions and pathways resulting in the breakdown of glutamate, the anion of 2-aminopentanedioic acid.


description: Catalysis of the reaction: UDP-glucose + ecdysteroid = UDP + glucosyl-ecdysteroid.


description: Catalysis of the reaction: 4-aminobenzoate + UDP-glucose = p-aminobenzoate-beta-D-glucopyranosyl ester + UDP.


deoxyribonucleoside metabolic process

description: The chemical reactions and pathways involving any one of a family of organic molecules consisting of a purine or pyrimidine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside).


flavonol metabolic process

description: The chemical reactions and pathways involving flavonols, a member of a class of vascular pigments formed by consecutive oxidative processes from the flavonoid intermediates flavanones and dihydroflavonols. Flavonols are the most widespread of the flavonoids and have a wide array of physiological activities.


name: negative regulation of striated muscle cell apoptotic process

description: Any process that decreases the rate or extent of striated muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a striated muscle cell and result in its death.


nitrobenzene catabolic process

description: The chemical reactions and pathways resulting in the breakdown of nitrobenzene.


organometal metabolic process

description: The chemical reactions and pathways involving organometals, any metal-containing organic compound, especially one in which the metal atom is linked directly to one of more carbon atoms.


N-succinyltransferase activity

description: Catalysis of the transfer of a succinyl group to a nitrogen atom on the acceptor molecule.


hypochlorous acid catabolic process

description: The chemical reactions and pathways resulting in the breakdown of hypochlorous acid.