thyroid hormone generation

description: The formation of either of the compounds secreted by the thyroid gland, mainly thyroxine and triiodothyronine. This is achieved by the iodination and joining of tyrosine molecules to form the precursor thyroglobin, proteolysis of this precursor gives rise to the thyroid hormones.


larval chitin-based cuticle development

category: biolink:BiologicalProcess biolink:Occurrent biolink:OntologyClass biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: Synthesis and deposition of a chitin-based larval cuticle. The insect larval cuticle is a secretion from epidermal cells that is shed at each molt. An example of this is found in Drosophila melanogaster.


name: regulation of cell-cell adhesion involved in gastrulation

description: Any process that modulates the frequency, rate, or extent of attachment of a cell to another cell affecting gastrulation.


name: cell wall beta-glucan biosynthetic process

description: The chemical reactions and pathways resulting in the formation of beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of cells.


name: positive regulation of hexasaccharide transport

description: Any process that activates or increases the frequency, rate or extent of hexasaccharide transport.


name: positive regulation of symbiont haustorium neck formation for entry into host

description: Any process that activates, maintains or increases the frequency, rate or extent of symbiont haustorium neck formation for entry into host. The host is defined as the larger of the organisms involved in a symbiotic interaction.


name: peptidyl-L-3-oxoalanine biosynthetic process from peptidyl-cysteine or peptidyl-serine

description: The modification of peptidyl-cysteine or peptidyl-serine to peptidyl-L-3-oxoalanine; characteristic of the active sites of arylsulfatases.


T-tubule organization

description: A process that is carried out at the cellular level that results in the assembly, arrangement of constituent parts, or disassembly of the T-tubule. A T-tubule is an invagination of the plasma membrane of a muscle cell that extends inward from the cell surface around each myofibril.


name: postnatal olfactory bulb interneuron migration

description: The migration of olfactory bulb interneuron precursors in the cerebral cortex that occurs after birth.


leptin-mediated signaling pathway

category: biolink:Pathway biolink:OntologyClass biolink:BiologicalProcess biolink:Occurrent biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: The series of molecular signals initiated by leptin binding to its receptor on the surface of a cell, and ending with the regulation of a downstream cellular process, e.g. transcription. Leptin is a hormone manufactured primarily in the adipocytes of white adipose tissue, and the level of circulating leptin is directly proportional to the total amount of fat in the body.


name: mesenchymal cell condensation involved in mammary fat development

description: The cell adhesion process in which mammary mesenchyme cells adhere to one another in the initial stages of the formation of mammary fat development.


oxytocin receptor activity

category: biolink:MolecularActivity biolink:Occurrent biolink:OntologyClass biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: Combining with oxytocin to initiate a change in cell activity.


name: positive regulation of adenylate cyclase-inhibiting opioid receptor signaling pathway

description: Any process that activates or increases the frequency, rate or extent of adenylate cyclase-inhibiting opioid receptor signaling pathway.


pectate disaccharide-lyase activity

description: Catalysis of the reaction: a pectate = a pectate + 4-(4-deoxy-alpha-D-galact-4-enuronosyl)-D-galacturonate. This reaction is the eliminative cleavage of 4-(4-deoxy-alpha-D-galact-4-enuronosyl)-D-galacturonate from the reducing end of pectate, i.e. de-esterified pectin.


thiocyanate isomerase activity

description: Catalysis of the reaction: benzyl isothiocyanate = benzyl thiocyanate.


branching morphogenesis of a nerve

description: The process in which the anatomical structures of branches in a nerve are generated and organized. This term refers to an anatomical structure (nerve) not a cell (neuron).


octopine metabolic process

description: The chemical reactions and pathways involving octopine, (N-(1-carboxy-4-guanidinobutyl)-L-alanine), an amino acid derived opine.


name: glutamate catabolic process to succinate via 2-oxoglutarate-dependent GABA-transaminase activity

description: The chemical reactions and pathways resulting in the breakdown of glutamate into succinate, that includes the conversion of 4-aminobutyrate to succinate semialdehyde by the 2-oxoglutarate-dependent gamma aminobutyrate (GABA) transaminase.


regulation of amine transport

description: Any process that modulates the frequency, rate or extent of the directed movement of amines into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


Langerhans cell differentiation

description: The process in which a precursor cell type acquires the specialized features of a Langerhans cell.


CAAX-box protein maturation

description: A series of specific posttranslational modifications to the CAAX box region of CAAX box proteins. CAAX box proteins are eukaryotic proteins that contain a CAAX motif where the C is a cysteine, the two A residues are aliphatic amino acids and the X can be one of several amino acids. The CAAX-box proteins undergo three sequential, enzymatic, post-translational modifications essential to their targeting: First, the proteins are prenylated by one of two prenyltransferases called farnesyltransferase and geranylgeranyltransferase-I. Prenylation results in the covalent attachment of either farnesyl or geranylgeranyl isoprenoid groups to the cysteine in the CAAX box motif. Prenylation is followed by proteolytic removal of the last three amino acids of the protein (AAX). Finally, the newly exposed carboxylate group of the isoprenylcysteine is methylated by an ER-associated prenyl-dependent carboxylmethyltransferase.


response to water deprivation

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a water deprivation stimulus, prolonged deprivation of water.


atrial septum primum morphogenesis

description: The process in which anatomical structure of an atrial septum primum is generated and organized.


mucosal lymphocyte homeostasis

description: The process of regulating the proliferation and elimination of lymphocytes such that the total number of lymphocytes within the mucosal tissue of an organism is stable over time in the absence of an outside stimulus.


name: cellular response to hydrostatic pressure

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrostatic pressure stimulus. Hydrostatic pressure is the force acting on an object in a system where the fluid is at rest (as opposed to moving). The weight of the fluid above the object creates pressure on it.


name: sialic acid transmembrane transporter activity

description: Enables the transfer of sialic acid from one side of a membrane to the other.


primary sex determination, soma

description: The transmission of information about sexual status from the initial, general, determination to signals specific to the soma.


name: plasma membrane proton-transporting ATP synthase complex assembly

description: The aggregation, arrangement and bonding together of a proton-transporting ATP synthase in the plasma membrane.


histone H2A kinase activity

description: Catalysis of the transfer of a phosphate group to a histone H2A.


carnitine 3-dehydrogenase activity

description: Catalysis of the reaction: carnitine + NAD+ = 3-dehydrocarnitine + H+ + NADH.


nitrate reductase (NADH) activity

description: Catalysis of the reaction: nitrite + NAD+ + H2O = nitrate + NADH + H+.


pH-gated sodium channel activity

description: A gated channel activity that enables the transmembrane transfer of a sodium ion by a channel that opens in response to a change in pH.


anterior midgut development

description: The process whose specific outcome is the progression of the anterior midgut over time, from its formation to the mature structure.


name: regulation of megakaryocyte differentiation

description: Any process that modulates the frequency, rate or extent of megakaryocyte differentiation.


aminodeoxyfutalosine synthase activity

description: Catalysis of the reaction: 3-[(1-carboxylatovinyl)oxy]benzoate(2-) + S-adenosyl-L-methionine + H2O = aminodeoxyfutalosinate + L-methionine + hydrogencarbonate + H+.


name: symbiont-mediated inactivation of host ribosome

description: A process in which a symbiont inhibits or disrupts translation of mRNA into protein in its host by inactivating its ribosomes.


Kdo transferase activity

description: Catalysis of the reactions: (KDO)-lipid IVA + CMP-3-deoxy-D-manno-octulosonate = KDO2-lipid IVA + CMP, and lipid IVA + CMP-3-deoxy-D-manno-octulosonate = (KDO)-lipid IVA + CMP.


protein localization to cell tip

description: A process in which a protein is transported to, or maintained in, a location at the cell tip.


name: D-arabinose 1-dehydrogenase (NADP+) activity

description: Catalysis of the reaction: D-arabinose + NADP+ = D-arabinono-1,4-lactone + NADPH.


name: symbiont-mediated suppression of host type II interferon-mediated signaling pathway

description: A process in which a symbiont interferes with, inhibits or disrupts a type II interferon-mediated signaling in the host organism. Type II interferon is also known as interferon-gamma.


name: positive regulation of skeletal muscle hypertrophy

description: Any process that activates or increases the frequency, rate or extent of skeletal muscle hypertrophy.


name: negative regulation of NK T cell differentiation

description: Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer T cell differentiation.


name: anther wall tapetum cell fate specification

description: The process in which a cell becomes capable of differentiating autonomously into a tapetal cell of anthers in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.


nitrogen cycle metabolic process

description: A nitrogen compound metabolic process that contributes to the nitrogen cycle. The nitrogen cycle is a series of metabolic pathways by which nitrogen is converted between various forms and redox states; it encompasses pathways in which nitrogen is acted upon directly, such as nitrification, denitrification, nitrogen fixation, and mineralization.


intercellular bridge organization

description: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the intracellular bridge. An intracellular bridge is a direct link between the cytoplasms of sister cells that allows cells to communicate with one another.


name: mesenchymal-endodermal cell signaling involved in lung induction

description: Any process that mediates the transfer of information from a mesenchymal cell to an endodermal cell in the foregut and contributes to the formation of the lung bud.


selenocysteine lyase activity

description: Catalysis of the reaction: L-selenocysteine + reduced acceptor = hydrogen selenide + L-alanine + acceptor.


cellular response to Gentian violet

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a Gentian violet stimulus.


myeloid dendritic cell activation

description: The change in morphology and behavior of a dendritic cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.


name: regulation of mononuclear cell migration

description: Any process that modulates the rate, frequency or extent of mononuclear cell migration. Mononuclear cell migration is the movement of a mononuclear cell within or between different tissues and organs of the body.


name: negative regulation of trichoblast fate specification

description: Any process that suppresses trichoblast fate specification.


description: Catalysis of the reaction: phenanthrene + O2 + NADH + H+ = H2O + NAD+ + phenanthrene-9,10-oxide.


bacitracin A catabolic process

description: The chemical reactions and pathways resulting in the breakdown of bacitracin A.


name: polyamine transmembrane transporter activity

description: Enables the transfer of polyamines, organic compounds containing two or more amino groups, from one side of a membrane to the other.


name: negative regulation of vein smooth muscle contraction

description: Any process that decreases the frequency, rate or extent of vein smooth muscle contraction.


alkylthioltransferase activity

description: Catalysis of the transfer of an alkylthio group from one compound (donor) to another (acceptor).


3-propylmalate synthase activity

description: Catalysis of the reaction: glyoxylate + H2O + pentanoyl-CoA = 3-propylmalate + CoA + H+.


L-xylulose reductase (NADPH) activity

description: Catalysis of the reaction: NADP+ + xylitol = L-xylulose + H+ + NADPH.


name: negative regulation of cholesterol metabolic process

description: Any process that decreases the rate, frequency, or extent of cholesterol metabolism, the chemical reactions and pathways involving cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.


regulation of pectin catabolic process

description: Any process that modulates the frequency, rate or extent of pectin catabolic process.


name: protein localization to adherens junction

description: Any process in which a protein is transported to, and/or maintained at the adherens junction.


response to bacteriocin

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bacteriocin stimulus. A bacteriocin is a protein substance released by certain bacteria that kills but does not lyse closely related strains of bacteria. Specific bacteriocins attach to specific receptors on cell walls and induce specific metabolic block, e.g. cessation of nucleic acid or protein synthesis of oxidative phosphorylation.


triethanolamine lyase activity

description: Catalysis of the reaction: triethanolamine = diethanolamine + acetaldehyde.


name: modulation of zoospore encystment on host

description: Any process that modulates the frequency, rate or extent of zoospore encystment on host. The host is defined as the larger of the organisms involved in a symbiotic interaction.


neuromast primordium migration

description: The migration of a cluster of a relatively undifferentiated cell originating at specific cephalic placodes and depositing proneuromasts along a developing lateral line, from which the neuromasts will develop.


histone H3S10 kinase activity

description: Catalysis of the reaction: histone H3-serine (position 10) + ATP = histone H3-phosphoserine (position 10) + ADP. This reaction is the addition of a phosphate group to the serine residue at position 10 of histone H3.


regulation of amyloid-beta clearance

description: Any process that modulates the frequency, rate or extent of amyloid-beta clearance.


name: regulation of dendritic cell differentiation

description: Any process that modulates the frequency, rate or extent of dendritic cell differentiation.


name: negative regulation of regulation of vascular associated smooth muscle cell membrane depolarization

description: Any process that stops, prevents or reduces the frequency, rate or extent of regulation of vascular smooth muscle cell membrane depolarization.


central B cell deletion

description: The deletion of B cells by apoptotic process occurring as part of central tolerance induction and B cell selection.


regulation of epinephrine secretion

description: Any process that modulates the frequency, rate or extent of the regulated release of epinephrine.


cresol catabolic process

description: The chemical reactions and pathways resulting in the breakdown of cresol, a mixture of the aromatic alcohol isoforms o-, p-, and m-cresol, which is obtained from coal tar or petroleum. The isomers are used as disinfectants, textile scouring agents, surfactants and as intermediates in the manufacture of salicylaldehyde, coumarin, and herbicides as well as being a major component of creosote.


cell wall disassembly

description: A process that results in the breakdown of the cell wall.


description: Catalysis of the reaction: 1,6-dihydroxy-2-methylcyclohexa-2,4-dienecarboxylate + NAD+ = 3-methylcatechol + CO2 + NADH.


tubuloglomerular feedback

description: The process in which blood volume is regulated due to a change in the rate of glomerular filtration. This is accomplished by a feedback mechanism that senses changes in the juxtaglomerular apparatus.


name: intracellularly ATP-gated chloride channel activity

description: Enables passage of a chloride ion through a transmembrane channel that opens when ATP is bound by the channel complex or one of its constituent parts on the intracellular side of the plasma membrane.


name: positive regulation of receptor-mediated virion attachment to host cell

description: Any process that activates or increases the frequency, rate or extent of receptor-mediated virion attachment to host cell.


name: 3-hydroxypropionate dehydrogenase (NADP+) activity

description: Catalysis of the reaction: 3-hydroxypropanoate + NADP+ = 3-oxopropanoate + H+ + NADPH.


membranous septum morphogenesis

description: The process in which the membranous septum is generated and organized. The membranous septum is the upper part of ventricular septum.


description: Catalysis of the reaction: beta-chaconine + UDP-L-rhamnose = H+ + alpha-chaconine + UDP.


cyanoalanine nitrilase activity

description: Catalysis of the reaction: 3-cyano-L-alanine + 2 H2O + H+ = L-aspartate + NH4.


name: gibberelli A15, 2-oxoglutarate:oxygen oxidoreductase activity

description: Catalysis of the reaction: gibberellin A15 + 2-oxoglutarate + O2 = gibberellin A24 + succinate + carbon dioxide + H2O.


name: positive regulation of heptasaccharide transport

description: Any process that activates or increases the frequency, rate or extent of heptasaccharide transport.


surface biofilm formation

description: A process in which planktonically growing microorganisms grow at the surface of a liquid-air interface and produce extracellular polymers that facilitate matrix formation, resulting in a change in the organisms' growth rate and gene transcription.


name: positive regulation of pyroptotic inflammatory response

description: Any process that increases the frequency, rate or extent of a pyroptotic inflammatory response.


lung epithelial cell differentiation

description: The process in which a relatively unspecialized cell acquires specialized features of an epithelial cell that contributes to the epithelium of the lung.


description: Catalysis of the transfer of an alpha-D-mannosyl residue from GDP-mannose into lipid-linked oligosaccharide, forming an alpha-(1->6)-D-mannosyl-D-mannose linkage.


uroporphyrinogen-III synthase activity

description: Catalysis of the reaction: hydroxymethylbilane = H2O + uroporphyrinogen III.


pyridoxamine phosphate oxidase activity

description: Catalysis of the reaction: pyridoxamine 5'-phosphate + H2O + O2 = pyridoxal 5'-phosphate + NH4+ + hydrogen peroxide. This activity can also oxidize pyridoxine 5'-phosphate to pyridoxal 5'-phosphate + hydrogen peroxide.


name: symbiont-mediated suppression of host immune response

description: A process in which a symbiont interferes with, inhibits or disrupts the normal execution of an immune response of the host organism. The immune response is any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat. The host is defined as the larger of the organisms involved in a symbiotic interaction.


name: leukemia inhibitory factor signaling pathway

description: The series of molecular signals initiated by the binding of a leukemia inhibitory factor to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.


name: regulation of malate dehydrogenase (decarboxylating) (NADP+) activity

description: Any process that modulates the frequency, rate or extent of malate dehydrogenase (decarboxylating) (NADP+) activity.


name: NAD(P)H dehydrogenase (quinone) activity

description: Catalysis of the reaction: NAD(P)H + H+ + a quinone = NAD(P)+ + a quinol.


response to proline

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a proline stimulus.


superoxide reductase activity

description: Catalysis of the reaction: superoxide + reduced rubredoxin + 2 H+ = H2O2 + rubredoxin.


name: regulation of post-embryonic root development

description: Any process that modulates the frequency, rate or extent of post-embryonic root development.


description: Catalysis of the reaction: acetyl-CoA + aminoglycoside = CoA + 1-N-acetylaminoglycoside. This is acetylation of the 1-amino group of the central deoxystreptamine ring.


name: phosphorelay response regulator activity

description: Responds to a phosphorelay sensor to initiate a change in cell state or activity. The activity of the response regulator is regulated by transfer of a phosphate from a histidine residue in the sensor, to an aspartate residue in the response regulator. Many but not all response regulators act as transcriptional regulators to elicit a response.


flavin prenyltransferase activity

description: Catalysis of the reaction: dimethylallylphosphate + FMNH2 = prenylated FMNH2 + phosphate.


trachea development

description: The process whose specific outcome is the progression of a trachea over time, from its formation to the mature structure. The trachea is the portion of the airway that attaches to the bronchi as it branches.


histamine binding

description: Binding to histamine, a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans.


neural tube formation

description: The formation of a tube from the flat layer of ectodermal cells known as the neural plate. This will give rise to the central nervous system.


name: negative regulation of SREBP signaling pathway

description: Any process that stops, prevents or reduces the frequency, rate or extent of the SREBP signaling pathway.


tRNA C5-cytosine methylation

description: The process whereby a cytosine in a tRNA is methylated at position 5 of the cytosine.


name: peripheral nervous system neuron axonogenesis

description: Generation of a long process from a neuron whose cell body resides in the peripheral nervous system. The axon carries action potential from the cell body towards target cells.


menaquinone catabolic process

description: The chemical reactions and pathways resulting in the breakdown of menaquinones, any of the quinone-derived compounds synthesized by intestinal bacteria. Structurally, menaquinones consist of a methylated naphthoquinone ring structure and side chains composed of a variable number of unsaturated isoprenoid residues. Menaquinones have vitamin K activity and are known as vitamin K2.


name: regulation of early endosome to late endosome transport

description: Any process that modulates the frequency, rate or extent of early endosome to late endosome transport.


UDP-glucose 6-dehydrogenase activity

description: Catalysis of the reaction: H2O + 2 NAD+ + UDP-alpha-D-glucose = 3 H+ + 2 NADH + UDP-alpha-D-glucuronate.


detection of UV

description: The series of events in which an ultraviolet radiation (UV light) stimulus is received and converted into a molecular signal. Ultraviolet radiation is electromagnetic radiation with a wavelength in the range of 10 to 380 nanometers.


anesthesia-resistant memory

description: The memory process that results in the formation of consolidated memory resistant to disruption of the patterned activity of the brain, without requiring protein synthesis.


collecting duct development

description: The process whose specific outcome is the progression of a collecting duct over time, from its formation to the mature structure. The collecting duct responds to vasopressin and aldosterone to regulate water, electrolyte and acid-base balance. It is the final common path through which urine flows before entering the ureter and then emptying into the bladder.


head kidney structural organization

description: The process that contributes to the act of creating the structural organization of the head kidney. This process pertains to the physical shaping of a rudimentary structure. The head kidney is a pronephros that consists of fused bilateral lobes located in the anterior part of the kidney.


(d)CMP kinase activity

description: Catalysis of the reaction: ATP + (d)CMP = ADP + (d)CDP.


name: Malpighian tubule stellate cell differentiation

description: The process in which a relatively unspecialized cell acquires specialized features of a Malpighian tubule stellate cell. A Malpighian tubule stellate cell is a specialized epithelial secretory cell that moves chloride ions and water across the tubule epithelium.


ectodermal placode development

description: The progression of an ectodermal placode over time from its initial formation until its mature state. An ectodermal placode is a thickening of the ectoderm that is the primordium of many structures derived from the ectoderm.


name: transcription-coupled nucleotide-excision repair, DNA damage recognition

description: The identification of lesions on the actively transcribed strand of the DNA duplex as well as a small subset of lesions not recognized by the general nucleotide-excision repair pathway.


description: Catalysis of the reaction: 2-aminobenzenesulfonate + 2 H+ + NADH + O2 = 2,3-dihydroxybenzenesulfonate + NAD+ + NH4. 2,3-dihydroxybenzenesulfonate is also known as 3-sulfocatechol.


description: Catalysis of the reaction: 2-hydroxy-6-oxo-(2'-aminophenyl)-hexa-2,4-dienoate + H2O = 2-aminobenzoate + cis-2-hydroxypenta-2,4-dienoate.


name: positive regulation of ribosome biogenesis

description: Any process that increases the rate, frequency or extent of ribosome biogenesis. Ribosome biogenesis is the cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits.


name: regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback

description: The process that modulates blood pressure by sensing the amount of stretch occurring in large arteries and responding to the input via central nervous system control.


name: myoblast maturation involved in muscle regeneration

description: A developmental process, independent of morphogenetic (shape) change, that is required for a myoblast cell to attain its fully functional state involved in muscle regeneration. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.


dicarboxylic acid catabolic process

description: The chemical reactions and pathways resulting in the breakdown of dicarboxylic acids, any organic acid containing two carboxyl (-COOH) groups.


name: negative regulation of cell morphogenesis

description: Any process that decreases the frequency, rate or extent of cell morphogenesis contributing to cell differentiation. Cell morphogenesis involved in differentiation is the change in form (cell shape and size) that occurs when relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history.


name: protein localization to T cell secretory granule

description: A process in which a protein is transported to, or maintained in, a location within a secretory granule in a T cell.


name: positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell

description: Any process that activates or increases the frequency, rate or extent of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell.


URM1 activating enzyme activity

description: Catalysis of the activation of the small ubiquitin-related modifier URM1, through the formation of an ATP-dependent high-energy thiolester bond.


jump response

description: The sudden, usually upward, movement off the ground or other surface through sudden muscular effort in the legs, following exposure to an external stimulus.


interleukin-16 receptor activity

description: Combining with interleukin-16 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


name: regulation of systemic arterial blood pressure by hormone

description: The process in which hormones modulate the force with which blood passes through the circulatory system. A hormone is one of a group of substances formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells, in the same organism, upon which they have a specific regulatory action.


retroviral 3' processing activity

description: The catalysis of the removal of two di- or tri-nucleotides from each 3' end of double-stranded viral DNA, exposing recessed 3' hydroxyls.


trophectodermal cell fate commitment

description: The cell fate commitment of precursor cells that will become trophectoderm cells.


name: negative regulation of digestive system process

description: Any process that decreases the frequency, rate or extent of a digestive system process, a physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism.


description: Catalysis of the endohydrolysis of (1->4)-beta-D-galactosidic linkages in blood group A and B substances.


endocrocin biosynthetic process

description: The chemical reactions and pathways resulting in the formation of endocrocin.


autophagosome membrane disassembly

description: The controlled breakdown of the membranes of autophagosomes.


name: regulation of prostaglandin catabolic process

description: Any process that modulates the frequency, rate or extent of prostaglandin catabolic process.


name: regulation of metanephric glomerular mesangial cell proliferation

description: Any process that modulates the frequency, rate or extent of metanephric glomerular mesangial cell proliferation.


name: positive regulation of anterograde axonal transport of mitochondrion

description: Any process that activates or increasesthe frequency, rate or extent of the directed movement of mitochondria along microtubules in axons away from the cell body and towards the presynapse.


name: positive regulation of Kit signaling pathway

description: Any process that activates or increases the frequency, rate or extent of Kit signaling pathway.


xanthine dehydrogenase activity

description: Catalysis of the reaction: xanthine + NAD+ + H2O = urate + NADH + H+.


name: phosphatidylglycerol-prolipoprotein diacylglyceryl transferase activity

description: Catalysis of the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the prospective N-terminal cysteine residue in an unmodified prolipoprotein.


name: epithelial cell-cell adhesion involved in epithelium migration

description: The attachment of an epithelial cell to another epithelial cell via adhesion molecules that contributes to epithelium migration.


beta-1,4-mannosyltransferase activity

description: Catalysis of the transfer of a mannose residue to an oligosaccharide, forming a beta-(1->4) linkage.


name: positive regulation of complement activation, lectin pathway

description: Any process that activates or increases the frequency, rate or extent of complement activation by the lectin pathway.


name: [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity

description: Catalysis of the reaction: 3'-phosphoadenylyl sulfate + [heparan sulfate]-glucosamine = adenosine 3',5'-bisphosphate + [heparan sulfate]-glucosamine 3-sulfate. The [heparan sulfate]-glucosamine 3-sulfate has a substrate consensus sequence of Glc(N2S>NAc)+/-6S GlcA GlcN2S*+/-6S GlcA>IdoA+/-2S Glc(N2S/NAc)+/-6S.


name: mycinamicin VI 2''-O-methyltransferase activity

description: Catalysis of the reaction: S-adenosyl-L-methionine + mycinamicin VI = S-adenosyl-L-homocysteine + mycinamicin III(1+) + H+.


description: Catalysis of the reaction: DNA containing 7-methyladenine + H2O = DNA with abasic site + 7-methyladenine. This reaction is the hydrolysis of DNA by cleavage of the N-C1' glycosidic bond between the damaged DNA 7-methyladenine and the deoxyribose sugar to remove the 7-methyladenine, leaving an abasic site.


phosphomethylpyrimidine kinase activity

description: Catalysis of the reaction: ATP + 4-amino-2-methyl-5-phosphomethylpyrimidine = ADP + 4-amino-2-methyl-5-diphosphomethylpyrimidine.


adenohypophysis morphogenesis

description: The process in which the anatomical structures of the adenohypophysis are generated and organized. The adenohypophysis is the anterior part of the pituitary. It secretes a variety of hormones and its function is regulated by the hypothalamus.


S-ribosylhomocysteine lyase activity

description: Catalysis of the reaction: S-(5-deoxy-D-ribos-5-yl)-L-homocysteine = (S)-4,5-dihydroxypentane-2,3-dione + L-homocysteine.


cuticle pattern formation

description: The regionalization process that gives rise to the patterns of cell differentiation in the cuticle.


name: cellular response to methamphetamine hydrochloride

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methamphetamine hydrochloride stimulus.


response to endothelin

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an endothelin stimulus. Endothelin is any of three secretory vasoconstrictive peptides (endothelin-1, -2, -3).


name: glyoxylate dehydrogenase (acylating) activity

description: Catalysis of the reaction: CoA + glyoxylate + NADP+ = H+ + NADPH + oxalyl-CoA.


response to epinephrine

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an epinephrine stimulus. Epinephrine is a catecholamine that has the formula C9H13NO3; it is secreted by the adrenal medulla to act as a hormone, and released by certain neurons to act as a neurotransmitter active in the central nervous system.


name: proximal/distal pattern formation involved in pronephric nephron development

description: The regionalization process in which specific areas of cell differentiation are determined along a proximal/distal axis of the pronephros.


name: regulation of toll-like receptor 15 signaling pathway

description: Any process that modulates the frequency, rate or extent of toll-like receptor 15 signaling pathway.


Cvt vesicle assembly

description: A vesicle organization process that takes place as part of the Cvt pathway, and results in the formation of a double membrane-bounded cytosolic structure that sequesters precursor aminopeptidase I (prAPI).


tissue migration

description: The process in which the population of cells that make up a tissue undergo directed movement.


name: regulation of interleukin-2-mediated signaling pathway

description: Any process that modulates the frequency, rate or extent of interleukin-2-mediated signaling pathway.


description: Catalysis of the reaction: monodemethylisoproturon + H2O = didemethylisoproturon + formaldehyde + 2 H+ + 2 e-.


starch, H2O dikinase activity

description: Catalysis of the reaction: n ATP + n H2O + starch = n AMP + n hydrogenphosphate + a 6-phosphogluco-amylopectin.


name: symbiont entry into host cell via permeabilization of host membrane

description: The entry of a symbiont into the cytoplasm of a host cell, triggered by an interaction between the bilayer of a host membrane and a membrane-penetration symbiont protein. This process mediates the entry of some non-enveloped virus into host cells, and results in the release of the virus contents into the host cell cytoplasm.


negative regulation of growth rate

description: Any process that reduces the rate of growth of all or part of an organism.


alpha-zingiberene synthase activity

description: Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = zingiberene + diphosphoric acid.


name: regulation of proanthocyanidin biosynthetic process

description: Any process that modulates the frequency, rate or extent of proanthocyanidin biosynthetic process.


name: negative regulation of tendon cell differentiation

description: Any process that stops, prevents or reduces the frequency, rate or extent of tendon cell differentiation.


name: positive regulation of ATF6-mediated unfolded protein response

description: Any process that activates or increases the frequency, rate or extent of the ATF6-mediated unfolded protein response.


cholesterol catabolic process

description: The chemical reactions and pathways resulting in the breakdown of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.


vesicle fusion with vesicle

description: Fusion of the membrane of a transport vesicle with a target membrane on another vesicle.


isoprenoid binding

description: Binding to an isoprenoid compound, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues.


name: neurotrophin TRK receptor signaling pathway

description: The series of molecular signals initiated by neurotrophin binding to its receptor on the surface of a target cell where the receptor possesses tyrosine kinase activity, and ending with the regulation of a downstream cellular process, e.g. transcription.


description: Catalysis of the reaction: H+ + phosphatidyl-L-serine = CO2 + phosphatidylethanolamine.


description: Catalysis of the reaction: 2-oxoglutarate + O2 + penicillin N = CO2 + deacetoxycephalosporin C + H2O + succinate.


cGMP catabolic process

description: The chemical reactions and pathways resulting in the breakdown of cyclic GMP, guanosine 3',5'-phosphate.


name: cyclic nucleotide-dependent protein kinase activity

description: cNMP-dependent catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein.


name: regulation of mRNA alternative polyadenylation

description: Any process that modulates the frequency, rate or extent of mRNA alternative polyadenylation.


response to copper ion starvation

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of copper ion.


NK T cell lineage commitment

description: The process in which a pro-T cell becomes committed to becoming an NK T cell.


suspensor development

description: The process whose specific outcome is the progression of the suspensor over time, from its formation to the mature structure. The suspensor is the extension at the base of the embryo that anchors the embryo in the embryo sac and pushes it into the endosperm.


name: monocoumaroyl dicaffeoyl spermidine meta-hydroxylase activity

description: Catalysis of the reaction: monocoumaroyl dicaffeoyl spermidine + NADPH + O2 = tricaffeoyl spermidine + NADP+ + H2O.


ureidoglycolate lyase activity

description: Catalysis of the reaction: (S)-ureidoglycolate = glyoxylate + urea.


endodermal cell fate determination

description: The cell fate determination process in which a cell becomes capable of differentiating autonomously into an endoderm cell regardless of its environment; upon determination, the cell fate cannot be reversed.


name: regulation of vesicle transport along microtubule

description: Any process that modulates the frequency, rate or extent of vesicle transport along microtubule.


name: late distal convoluted tubule development

description: The process whose specific outcome is the progression of the late distal convoluted tubule over time, from its formation to the mature structure. The late distal convoluted tubule contains DCT cells and intercalated (IC) alpha and beta cells and is vasopressin-sensitive.


name: negative regulation of N',N'',N'''-triacetylfusarinine C biosynthetic process

description: Any process that stops, prevents or reduces the frequency, rate or extent of N',N'',N'''-triacetylfusarinine C biosynthetic process.


name: regulation of long-chain fatty acid import into cell

description: Any process that modulates the frequency, rate or extent of long-chain fatty acid import into a cell.


name: negative regulation of pollen tube guidance

description: Any process that decreases the rate, frequency or extent of pollen tube guidance towards ovules. This is one mechanism to prevent polytuby, the simultaneous penetration of ovules by multiple pollen tubes.


name: oxidation-dependent protein catabolic process

description: The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the oxidation of one or more amino acid residues in the protein.


terephthalate decarboxylase activity

description: Catalysis of the reaction: terephthalate + H2O = benzoate + HCO3-.


XTP binding

description: Binding to XTP.


gamma-tubulin complex assembly

description: The aggregation, arrangement and bonding together of a set of components to form a gamma-tubulin complex.


fibroblast migration

description: Cell migration that is accomplished by extension and retraction of a fibroblast pseudopodium. A fibroblast is a connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules.


name: regulation of intrinsic apoptotic signaling pathway in response to osmotic stress

description: Any process that modulates the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to osmotic stress.


melatonin receptor activity

description: Combining with melatonin, N-acetyl-5-methoxytryptamine, to initiate a change in cell activity. Melatonin is a neuroendocrine substance that stimulates the aggregation of melanosomes in melanophores, thus lightening the skin.


name: positive regulation of tumor necrosis factor-mediated signaling pathway

description: Any process that activates or increases the frequency, rate or extent of tumor necrosis factor-mediated signaling pathway.


hemoglobin biosynthetic process

description: The chemical reactions and pathways resulting in the formation of hemoglobin, an oxygen carrying, conjugated protein containing four heme groups and globin.


name: positive regulation of transepithelial migration of symbiont in host

description: Any process that activates or increases the frequency, rate or extent of transepithelial migration of symbiont in host.


adenosylcobinamide kinase activity

description: Catalysis of the reaction: RTP + adenosylcobinamide = adenosylcobinamide phosphate + RDP (where RTP is either ATP or GTP).


description: Catalysis of the reaction: 1-chloro-2,2-bis(4-chlorophenyl)ethene + 2 H+ + 2 e- = 1-chloro-2,2-bis(4-chlorophenyl)ethane. 1-chloro-2,2-bis(4-chlorophenyl)ethene is also known as DDMU; 1-chloro-2,2-bis(4-chlorophenyl)ethane is also known as DDMS.


name: glutamine family amino acid biosynthetic process

description: The chemical reactions and pathways resulting in the formation of amino acids of the glutamine family, comprising arginine, glutamate, glutamine and proline.


name: diphthine methyl ester synthase activity

description: Catalysis of the reaction: 2-[(3S)-amino-3-carboxypropyl]-L-histidyl-[translation elongation factor 2] + 4 S-adenosyl-L-methionine = diphthine methyl ester-[translation elongation factor 2] + 3 H+ + 4 S-adenosyl-L-homocysteine.


methanophenazine biosynthetic process

description: The chemical reactions and pathways resulting in the formation of methanophenazine.


phenylserine aldolase activity

description: Catalysis of the reaction: L-threo-3-phenylserine = benzaldehyde + glycine.


name: protein localization to mitotic spindle pole body

description: A process in which a protein is transported to, or maintained in, a location within a mitotic spindle pole body.


peripheral B cell negative selection

description: Any process leading to negative selection of B cells in the periphery.


mast cell proliferation

description: The expansion of a mast cell population by cell division.


p-cymene catabolic process

description: The chemical reactions and pathways resulting in the breakdown of p-cymene, 1-methyl-4-isopropylbenzene, one of the alkyl-substituted aromatic hydrocarbons found in volatile oils from over 100 plants.


name: symbiont-mediated perturbation of host cell cycle G1/S transition checkpoint

description: A process in which a symbiont interferes with the normal execution of the host cell G1/S transition checkpoint. The host is defined as the larger of the organisms involved in a symbiotic interaction.


glucocorticoid biosynthetic process

description: The chemical reactions and pathways resulting in the formation of glucocorticoids, hormonal C21 corticosteroids synthesized from cholesterol.


epithelial cell-cell adhesion

description: The attachment of an epithelial cell to another epithelial cell via adhesion molecules.


name: non-recombinational interstrand cross-link repair

description: Removal of a DNA interstrand crosslink (a covalent attachment of DNA bases on opposite strands of the DNA) and restoration of the DNA by a mechanism that does not involve homologous DNA recombination.


tartrate dehydrogenase activity

description: Catalysis of the reaction: tartrate + NAD+ = oxaloglycolate + NADH + H+.


toluene-4-sulfonate metabolic process

description: The chemical reactions and pathways involving toluene-4-sulfonate, the anion of 4-toluene sulfonic acid, a white crystalline solid which is highly hygroscopic and soluble in water.


hopanoid metabolic process

description: The chemical reactions and pathways involving hopanoids, pentacyclic sterol-like compounds based on the hopane nucleus.


response to host defenses

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detecting the defenses of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.


name: 2,2-dialkylglycine decarboxylase (pyruvate) activity

description: Catalysis of the reaction: 2,2-dialkylglycine + H+ + pyruvate = L-alanine + CO2 + dialkyl ketone.


name: iron incorporation into iron-sulfur cluster via tetrakis-L-cysteinyl triiron tetrasulfide

description: The incorporation of iron into a 3Fe-4S iron-sulfur cluster via tetrakis-L-cysteinyl triiron tetrasulfide.


pronephric glomerulus development

description: The progression of the glomerulus of the pronephric kidney over time from its initial formation until its mature state. The pronephric glomerulus is part of the pronephric nephron and is restricted to one body segment.


name: regulation of (1->3)-beta-D-glucan metabolic process

description: Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving (1->3)-beta-D-glucans.


meristem structural organization

description: Organization of a region of tissue in a plant that is composed of one or more undifferentiated cells capable of undergoing mitosis and differentiation, thereby effecting growth and development of a plant by giving rise to more meristem or specialized tissue.


methylguanidinase activity

description: Catalysis of the reaction: H2O + methylguanidine = methylammonium + urea.


cellular response to vitamin B3

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin B3 stimulus.


description: The chemical reactions and pathways involving (-)-exo-alpha-bergamotene.


name: phosphatidylcholine biosynthesis from phosphoryl-ethanolamine via N-dimethylethanolamine phosphate and CDP-choline

description: The phosphatidylcholine biosynthetic process that begins with three consecutive N-methylation steps that are carried out on phospho-bases, phosphoethanolamine, phospho-N-methylethanolamine, and phospho-N-dimethylethanolamine; the process ends with the conversion of a phosphatidyl-N-dimethylethanolamine to a phosphatidylcholine.


malate metabolic process

description: The chemical reactions and pathways involving malate, the anion of hydroxybutanedioic acid, a chiral hydroxydicarboxylic acid. The (+) enantiomer is an important intermediate in metabolism as a component of both the TCA cycle and the glyoxylate cycle.


name: regulation of positive chemotaxis to cAMP by chlorinated alkylphenone

description: Any process that modulates the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of a chlorinated alkylphenone. An alkylphenone is an aromatic polyketide with methyl and chlorine substitutions.


description: Catalysis of the reaction: S-adenosyl-L-methionine + phenylethanolamine = S-adenosyl-L-homocysteine + N-methylphenylethanolamine.


cerebral cortex regionalization

description: The regionalization process that results in the creation of areas within the cerebral cortex that will direct the behavior of cell migration and differentiation as the cortex develops.


ectodermal digestive tract development

description: The process whose specific outcome is the progression of the ectodermal digestive tract over time, from its formation to the mature structure. The ectodermal digestive tract includes those portions that are derived from ectoderm.


name: embryonic skeletal limb joint morphogenesis

description: The process, occurring in the embryo, in which the anatomical structures of a skeletal limb joint are generated and organized. A skeletal limb joint is the connecting structure between the bones of a limb.


description: Catalysis of the reaction: L-proline + NADP+ = 1-pyrroline-5-carboxylate + NADPH + H+.


description: Catalysis of the reaction: (R)-2-hydroxyisocaproate + isocaproyl-CoA = (R)-2-hydroxyisocaproyl-CoA + isocaproate.


name: postsynaptic neurotransmitter receptor diffusion trapping

description: The process by which diffusing neurotransmitter receptor becomes trapped at the postsynaptic specialization membrane. This is typically due to interaction with components of the post-synaptic specialization.


carbon fixation by acetyl-CoA pathway

description: A pathway of carbon dioxide fixation in which one molecule of acetyl-CoA is completely synthesized from two molecules of carbon dioxide (CO2).


brain segmentation

description: Division of the brain into a series of semi-repetitive parts or segments.


receptor localization to synapse

description: Any process in which a receptor is transported to, and/or maintained at the synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell.


T cell extravasation

description: The migration of a T cell from the blood vessels into the surrounding tissue.


globoside metabolic process

description: The chemical reactions and pathways involving globosides, globotetraosylceramides, ceramides containing a core structure of GalNAc-beta-(1->3)-Gal-alpha-(1->4)-Glc(I). Globosides are the major neutral glycosphingolipid in normal kidneys and erythrocytes.


name: cardiac muscle cell myoblast differentiation

description: The process in which a relatively unspecialized cell acquires specialized features of a cardiac myoblast. A cardiac myoblast is a precursor cell that has been committed to a cardiac muscle cell fate but retains the ability to divide and proliferate throughout life.


description: Catalysis of the reaction: 2-hydroxyisobutyrate = H2O + methacrylate.


name: metanephric mesenchymal cell differentiation

description: The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesenchymal cells of the metanephros as it progresses from its formation to the mature state.


strigolactone biosynthetic process

description: The chemical reactions and pathways resulting in the formation of strigolactone.


name: extracellular phenylacetaldehyde-gated monoatomic ion channel activity

description: Enables the transmembrane transfer of an ion by a channel that opens when extracellular phenylacetaldehyde has been bound by the channel complex or one of its constituent parts.


aerenchyma formation

description: The process that gives rise to aerenchyma, parenchyma tissue containing particularly large intercellular spaces of schizogenous or lysigenous origin. This process pertains to the initial formation of a structure from unspecified parts.


bulbus arteriosus formation

description: The developmental process pertaining to the initial formation of the bulbus arteriosus from unspecified parts. The bulbus arteriosus is an elastic chamber of the heart.


name: tetrahydrothiophene 1-oxide reductase activity

description: Catalysis of the reaction: tetrahydrothiophene 1-oxide + reduced acceptor = tetrahydrothiophene + acceptor.


tetrahydrobiopterin binding

description: Binding to a tetrahydrobiopterin, 5,6,7,8-tetrahydrobiopterin or a derivative thereof; tetrahydrobiopterins are enzyme cofactors that carry electrons in redox reactions.


name: immunoglobulin production in mucosal tissue

description: The synthesis and release of immunoglobulin in the mucosal tissue.


purine deoxyribonucleoside salvage

description: Any process which produces a purine deoxyribonucleoside from derivatives of it, without de novo synthesis.


description: Catalysis of the reaction: cobalt-precorrin 5A + H2O = cobalt-precorrin 5B + acetaldehyde + H+.


name: cell wall (1->3)-alpha-glucan biosynthetic process

description: The chemical reactions and pathways resulting in the formation of (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-glucosidic bonds, found in the walls of cells.


name: negative regulation of macrophage derived foam cell differentiation

description: Any process that decreases the rate, frequency or extent of macrophage derived foam cell differentiation. Macrophage derived foam cell differentiation is the process in which a macrophage acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions.


2 iron, 2 sulfur cluster binding

description: Binding to a 2 iron, 2 sulfur (2Fe-2S) cluster; this cluster consists of two iron atoms, with two inorganic sulfur atoms found between the irons and acting as bridging ligands.


mitotic checkpoint complex assembly

description: The aggregation, arrangement and bonding together of a set of components to form a mitotic checkpoint complex.


renal protein absorption

description: A renal system process in which proteins are taken up from the collecting ducts, glomerulus and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures (e.g. protein absorption is observed in nephrocytes in Drosophila, see PMID:23264686).


pallium glioblast division

description: The division of a glioblast in the pallium. A glioblast is a dividing precursor cell that gives rise to glial cells.


response to 5-fluoro-2'-deoxyuridine

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 5-fluoro-2'-deoxyuridine stimulus. 5-fluoro-2'-deoxyuridine is a pyrimidine 2'-deoxyribonucleoside compound having 5-fluorouracil as the nucleobase; it is used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.


trigeminal ganglion morphogenesis

description: The process in which the anatomical structure of a trigeminal ganglion is generated and organized.


name: regulation of systemic arterial blood pressure by epinephrine

description: The regulation of blood pressure mediated by the catecholamine signaling molecule epinephrine.


macrophage cytokine production

description: The appearance of a macrophage cytokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


name: mitochondria-associated ubiquitin-dependent protein catabolic process

description: The chemical reactions and pathways resulting in the breakdown of proteins transported from mitochondria and targeted to cytoplasmic proteasomes for degradation as a response to oxidative stress conditions.


name: negative regulation of cardiac muscle cell differentiation

description: Any process that stops, prevents or reduces the frequency, rate or extent of cardiac muscle cell differentiation.


intracellular copper ion homeostasis

description: A homeostatic process involved in the maintenance of a steady state level of copper ions within a cell.


name: circadian regulation of heart rate by the suprachiasmatic nucleus

description: The process in which the suprachiasmatic nucleus modulates heart rate at different values with a regularity of approximately 24 hours.


auxin receptor activity

description: Combining with auxin and transmitting the signal in the cell to initiate a change in cell activity. Auxin is a plant hormone (phytohormone).


name: regulation of tube diameter, open tracheal system

description: Ensuring that a tube in an open tracheal system is of the correct diameter. When primary branches form their lumens are small (less than 2 micrometers) in caliber and must undergo regulated expansion during larval life to reach their mature size.


name: positive regulation of the force of heart contraction by epinephrine-norepinephrine

description: Any process that increases the force with which the cardiac muscles of the heart pump blood through the circulatory system as a result of the presence of epinephrine or norepinephrine in the bloodstream or released from the nerve endings.


name: protein-heme P460 linkage via heme P460-bis-L-cysteine-L-tyrosine

description: The linkage of protein to heme P460 via heme P460-bis-L-cysteine-L-tyrosine.


response to TNF agonist

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a TNF agonist stimulus.


B cell apoptotic process

description: Any apoptotic process in a B cell, a lymphocyte of B lineage with the phenotype CD19-positive and capable of B cell mediated immunity.


cellular response to indole-3-methanol

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an indole-3-methanol stimulus.


name: tricarboxylate secondary active transmembrane transporter activity

description: Enables the transfer of tricarboxylate from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters.


name: inositol diphosphate pentakisphosphate diphosphatase activity

description: Catalysis of the reaction: diphospho-1D-myo-inositol pentakisphosphate + H2O = 1D-myo-inositol hexakisphosphate + phosphate.


U7 snRNA binding

description: Binding to a U7 small nuclear RNA (U7 snRNA).


estrous cycle

description: A type of ovulation cycle, which occurs in most mammalian therian females, where the endometrium is resorbed if pregnancy does not occur.


name: intermediate mesoderm structural organization

description: The process that contributes to the act of creating the structural organization of the intermediate mesoderm. This process pertains to the physical shaping of a rudimentary structure.


(S)-2-methylmalate dehydratase activity

description: Catalysis of the reaction: S-citramalate = H2O + mesaconate.


regulation of motor neuron migration

description: Any process that modulates the frequency, rate or extent of motor neuron migration.


name: regulation of cardiac muscle cell contraction

description: Any process that modulates the frequency, rate or extent of cardiac muscle cell contraction.


ABC-type cadmium transporter activity

description: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Cd (cytosol) = ADP + phosphate + Cd (vacuole).


negative regulation of glucose import

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the import of the hexose monosaccharide glucose into a cell or organelle.


name: nucleotide-excision repair involved in interstrand cross-link repair

description: Any nucleotide-excision repair that is involved in interstrand cross-link repair.


cellular response to histamine

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a histamine stimulus. Histamine, the biogenic amine 2-(1H-imidazol-4-yl)ethanamine, is involved in local immune responses as well as regulating physiological function in the gut and acting as a neurotransmitter.


flavone apiosyltransferase activity

description: Catalysis of the reaction: UDP-apiose + 7-O-beta-D-glucosyl-5,7,4'-trihydroxyflavone = UDP + 7-O-(beta-D-apiofuranosyl-1,2-beta-D-glucosyl)-5,7,4'-trihydroxyflavone.


name: regulation of ventricular cardiac muscle cell membrane depolarization

description: Any process that modulates the establishment or extent of a membrane potential in the depolarizing direction away from the resting potential in a ventricular cardiomyocyte.


presynapse to nucleus signaling pathway

description: The series of molecular signals that conveys information from the presynapse to the nucleus via cytoskeletal transport of a protein from a presynapse to the component to the nucleus where it affects biochemical processes that occur in the nucleus (e.g DNA transcription, mRNA splicing, or DNA/histone modifications).


name: self-resistance to endogenously produced metabolite

description: A process that reduces or removes the toxicity of an endogenously produced substance. Mechanisms of resistance to endogenously produced compounds include modification the compound, export, sequestration, or mutations in the target enzyme.


N-acylglucosamine 2-epimerase activity

description: Catalysis of the reaction: N-acyl-D-glucosamine = N-acyl-D-mannosamine.


neural tube closure

description: The last step in the formation of the neural tube, where the paired neural folds are brought together and fuse at the dorsal midline.


protein localization to trailing edge

description: A process in which a protein is transported to, or maintained at, the trailing edge. The trailing edge is the area of a motile cell opposite to the direction of movement.


name: regulation of phenazine biosynthetic process

description: Any process that modulates the frequency, rate or extent of phenazine biosynthetic process.


purine ribonucleotide binding

description: Binding to a purine ribonucleotide, any compound consisting of a purine ribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety.


eurydendroid cell differentiation

description: The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature eurydendroid cell. Differentiation includes the processes involved in commitment of a neuroblast to a eurydendroid cell fate. A eurydendroid cell is an efferent neuron found in the cerebellar cortex of teleosts.


anterior lateral line development

description: The process whose specific outcome is the progression of the anterior lateral line over time, from its formation to the mature structure. The anterior lateral line consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the head of all fishes and most amphibians. The anterior lateral line develops from cranial ectodermal placodes situated between the eye and ear.


vacuolar protein processing

description: Protein processing that takes place in the vacuole. Most protein processing in the vacuole represents proteolytic cleavage of precursors to form active enzymes.


lymphocyte migration into lymph node

description: The movement of a lymphocyte within the lymphatic system into a lymph node, and its subsequent positioning within defined functional compartments such as sites of cell activation by antigen.


name: negative regulation of Wnt signaling pathway, planar cell polarity pathway

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the Wnt signaling pathway, planar cell polarity pathway.


name: negative regulation of glomerular filtration by angiotensin

description: The process in which angiotensin directly decreases the rate of glomerular filtration in the kidney. Glomerular filtration is the process whereby blood is filtered by the glomerulus into the renal tubule.


name: regulation of positive thymic T cell selection

description: Any process that modulates the frequency, rate or extent of positive thymic T cell selection.


name: cellular response to decreased oxygen levels

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting a decline in the level of oxygen.


L-arabinose biosynthetic process

description: The chemical reactions and pathways resulting in the formation of L-arabinose, arabino-pentose.


Leydig cell proliferation

description: The multiplication or reproduction of Leydig cells, resulting in the expansion of a cell population. Leydig cells are interstitial cells located adjacent to the seminiferous tubules in the testis which produce testosterone.


description: The methylation of the N-terminal phenylalanine of proteins to form the derivative N-methyl-L-phenylalanine.


'de novo' CTP biosynthetic process

description: The chemical reactions and pathways resulting in the formation of cytidine 5'-triphosphate (CTP) from simpler components.


name: regulation of gastric mucosal blood circulation

description: Any process that modulates the frequency, rate or extent of gastric mucosal blood circulation.


name: histone H4K16 acetyltransferase activity

description: Catalysis of the reaction: acetyl-CoA + histone H4 L-lysine (position 16) = CoA + histone H4 N6-acetyl-L-lysine (position 16). This reaction represents the addition of an acetyl group to the lysine at position 16 of histone H4.


name: regulation of establishment of competence for transformation

description: Any process that modulates the frequency, rate or extent of the process in which a cell becomes able to take up and incorporate extracellular DNA into its genome.


GGU codon-amino acid adaptor activity

description: A triplet codon-amino acid adaptor activity that recognizes a GGU codon.


cardiac right ventricle morphogenesis

description: The process in which the right cardiac ventricle is generated and organized.


isopullulanase activity

description: Catalysis of the hydrolysis of pullulan to isopanose (6-alpha-maltosylglucose).


name: phosphatidylethanolamine:Kdo2-lipid A phosphoethanolamine transferase activity

description: Catalysis of the reaction: Kdo2-lipid A + phosphatidylethanolamine = phosphoethanolamine-Kdo2-lipid A + diacylglycerol.


central B cell tolerance induction

description: Tolerance induction of B cells in the bone marrow.


name: CD4-positive gamma-delta intraepithelial T cell differentiation

description: The process in which a precursor cell type acquires the specialized features of a CD4-positive, gamma-delta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways.


description: The chemical reactions and pathways resulting in the breakdown of N(omega),N(omega)-dimethyl-L-arginine, a methyl-L-arginine having two methyl groups both attached to the primary amino moiety of the guanidino group.


dimethyl ether metabolic process

description: The chemical reactions and pathways involving dimethyl ether, CH3-O-CH3, the simplest ether. Dimethyl ether, also known wood ether and methyl ether, is a colorless gas that has been used in refrigeration applications.


name: regulation of systemic arterial blood pressure mediated by a chemical signal

description: The regulation of blood pressure mediated by biochemical signaling: hormonal, autocrine or paracrine.


description: Catalysis of the reaction: [(1->3)-beta-D-glucosyl](n) + phosphate = [(1->3)-beta-D-glucosyl](n-1) + alpha-D-glucose 1-phosphate; substrates include laminarin.


name: positive regulation of peptidoglycan recognition protein signaling pathway

description: Any process that increases the rate, frequency, or extent of the peptidoglycan recognition protein signaling pathway.


name: glucosylglycerol transmembrane transporter activity

description: Enables the transfer of a glucosylglycerol from one side of a membrane to the other. A glucosylglycerol is an alpha-D-glucopyranosyl-alpha-(1,2)-glycerol.


name: modulation of blood pressure in another organism

description: A process by which one organism modulates the force with which blood travels through the circulatory system of another organism.


name: positive regulation of CD8-positive, alpha-beta T cell activation

description: Any process that activates or increases the frequency, rate or extent of CD8-positive, alpha-beta T cell activation.


extracellular exosome biogenesis

description: The assembly and secretion of an extracellular exosome, a membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane.


peptidyl-proline 3-dioxygenase activity

description: Catalysis of the reaction: peptidyl L-proline + 2-oxoglutarate + O2 = peptidyl trans-3-hydroxy-L-proline + succinate + CO2.


spore wall biogenesis

description: A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a spore wall. A spore wall is the specialized cell wall lying outside the cell membrane of a spore.


hindbrain development

description: The process whose specific outcome is the progression of the hindbrain over time, from its formation to the mature structure. The hindbrain is the posterior of the three primary divisions of the developing chordate brain, or the corresponding part of the adult brain (in vertebrates, includes the cerebellum, pons, and medulla oblongata and controls the autonomic functions and equilibrium).


compartment boundary maintenance

description: A homeostatic process involved in the maintenance of a compartment boundary. A compartment boundary is a lineage restriction boundary within a developing tissue which does not correspond to some morphological barrier.


name: beta-galactoside (CMP) alpha-2,3-sialyltransferase activity

description: Catalysis of the reaction: CMP-N-acetylneuraminate + beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl-R = CMP + alpha-N-acetylneuraminyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl-R.


description: Catalysis of the reaction: S-adenosyl-L-methionine + ethanolamine phosphate = S-adenosyl-L-homocysteine + N-methylethanolamine phosphate.


GGC codon-amino acid adaptor activity

description: A triplet codon-amino acid adaptor activity that recognizes a GGC codon.


name: positive regulation of methanophenazine biosynthetic process

description: Any process that activates or increases the frequency, rate or extent of methanophenazine biosynthetic process.


codeine metabolic process

description: The chemical reactions and pathways involving codeine, an alkaloid found in the opium poppy, Papaver somniferum var. album. Codeine has analgesic, anti-tussive and anti-diarrhoeal properties.


name: regulation of retinal rod cell fate commitment

description: Any process that modulates the process in which the developmental fate of a cell becomes restricted such that it will develop into a retinal rod cell. A retinal rod cell is one of the two photoreceptor subtypes in a camera-type eye.


description: Catalysis of the oxidative decarboxylation of 6-hydroxynicotinate to 2,5-dihydroxypyridine, dependent on O2, NADH +H+ and FAD.


sucrose alpha-glucosidase activity

description: Catalysis of the reaction: sucrose + H2O = alpha-D-glucose + beta-D-fructose.


regulation of steroid hormone secretion

description: Any process that modulates the frequency, rate or extent of steroid hormone secretion.


name: isopentenyl diphosphate biosynthetic process, mevalonate pathway involved in terpenoid biosynthetic process

description: The chemical reactions and pathways resulting in the formation of isopentenyl diphosphate by the mevalonate pathway that contributes to terpenoid biosynthesis. This pathway converts acetate, in the form of acetyl-CoA, to isopentenyl diphosphate (IPP) through a series of mevalonate intermediates.


name: 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process

description: The chemical reactions and pathways resulting in the formation of 3'-phosphoadenosine 5'-phosphosulfate, a naturally occurring mixed anhydride. It is an intermediate in the formation of a variety of sulfo compounds in biological systems.


response to cyanide

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cyanide stimulus.


(S)-corytuberine synthase activity

description: Catalysis of the reaction: H+ + (S)-reticulinium(1+) + NADPH + O2 = (S)-corytuberine + NADP + 2 H2O.


name: NADPH-dependent dihydrocurcumin reductase activity

description: Catalysis of the reaction: dihydrocurcumin + NADPH+ + H+ = tetrahydrocurcumin + NADP+.


name: regulation of macrophage tolerance induction

description: Any process that modulates the frequency, rate, or extent of macrophage tolerance induction.


mast cell homeostasis

description: The process of regulating the proliferation and elimination of mast cells such that the total number of mast cells within a whole or part of an organism is stable over time in the absence of an outside stimulus.


name: heparan sulfate N-acetylglucosaminyltransferase activity

description: Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + heparan sulfate = UDP + (N-acetyl-D-glucosaminyl)-heparan sulfate.


tetraterpenoid catabolic process

description: The chemical reactions and pathways resulting in the breakdown of tetraterpenoid compounds, terpenoids with eight isoprene units.


name: vitexin 2''-O-rhamnoside 7-O-methyltransferase activity

description: Catalysis of the reaction: S-adenosyl-L-methionine + vitexin 2''-O-beta-L-rhamnoside = S-adenosyl-L-homocysteine + 7-O-methylvitexin 2''-O-beta-L-rhamnoside.


mesonephric mesenchyme development

description: The biological process whose specific outcome is the progression of a mesonephric mesenchyme from an initial condition to its mature state. This process begins with the formation of mesonephric mesenchyme and ends with the mature structure. Mesonephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the mesonephros.


fatty acid derivative catabolic process

description: The chemical reactions and pathways resulting in the breakdown of fatty acid derivative.


sodium-dependent self proteolysis

description: The sodium-dependent hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their own peptide bonds.


name: negative regulation of Wnt signaling pathway, calcium modulating pathway

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors leads to an increase in intracellular calcium and activation of protein kinase C (PKC).


regulation of miRNA metabolic process

description: Any process that modulates the frequency, rate or extent of miRNA metabolic process.


name: protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity

description: Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + D-fructose(out) = protein cysteine + D-fructose-1-phosphate(in).


guanosine deaminase activity

description: Catalysis of the reaction: guanosine + H2O = xanthosine + NH3.


name: acetate transmembrane transporter activity

description: Enables the transfer of acetate from one side of a membrane to the other. Acetate is the 2-carbon carboxylic acid ethanoic acid.


thigmotropism

description: The movement of an organism, or part of an organism, such as leaves or tendrils, in response to a touch stimulus, usually toward or away from it.


description: Catalysis of the reaction: S-methyl-5-thio-alpha-D-ribose 1-phosphate = S-methyl-5-thio-D-ribulose 1-phosphate.


auxin conjugate metabolic process

description: The chemical reactions and pathways involving auxin conjugates, a bound form of auxin.


name: benzene-containing compound metabolic process

description: The chemical reactions and pathways involving benzene, C6H6, a volatile, very inflammable liquid, contained in the naphtha produced by the destructive distillation of coal, from which it is separated by fractional distillation, or any of its derivatives.


trihydroxytoluene dioxygenase activity

description: Catalysis of the reaction: 2,3,5-trihydroxytoluene + O2 = 2,4,6-trioxoheptanoate.


S-methylmethionine biosynthetic process

description: The chemical reactions and pathways resulting in the formation of S-methyl-methionine (SMM) from methionine and S-adenosyl-methionine (Ado-Met), catalyzed by methionine S-methyltransferase (MMT). SMM can be reconverted to methionine by donating a methyl group to homocysteine, and concurrent operation of this reaction and that mediated by MMT sets up the SMM cycle.


versiconal reductase activity

description: Catalysis of the reaction: versiconol + NADP = versiconal hemiacetal + NADPH + H+.


D-xylose fermentation

description: The anaerobic enzymatic conversion of D-xylose to ethanol, yielding energy in the form of ATP.


name: regulation of endoplasmic reticulum unfolded protein response

description: Any process that modulates the frequency, rate or extent of endoplasmic reticulum unfolded protein response.


name: negative regulation of toll-like receptor signaling pathway

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor signaling pathway.


name: iron incorporation into iron-sulfur cluster via tris-L-cysteinyl L-cysteine persulfido L-glutamato L-histidino L-serinyl nickel triiron disulfide trioxide

description: The incorporation of iron into a 3Fe-2S cluster by tris-L-cysteinyl L-cysteine persulfido L-glutamato L-histidino L-serinyl nickel triiron disulfide trioxide.


helper T cell diapedesis

description: The passage of a helper T cell between the tight junctions of endothelial cells lining blood vessels, typically the fourth and final step of cellular extravasation.


pollen wall assembly

description: The formation of reticulate pollen wall pattern consisting of two layers, exine and intine.


phytol kinase activity

description: Catalysis of the reaction: phytol + CTP = phytyl monophosphate + CDP + H+.


name: protein-disulfide reductase (glutathione) activity

description: Catalysis of the reaction: 2 glutathione + protein-disulfide = glutathione disulfide+ protein-dithiol.


cellular response to heparin

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heparin stimulus.


name: cyclization of glutamine involved in intein-mediated protein splicing

description: The cyclization of glutamine to yield an L-glutamimide residue at the C-terminus of an excised intein during protein splicing.


name: symbiont-mediated perturbation of host tight cell-cell junction

description: The process in which an organism effects a change that impairs the structure or temporarily subverts the tight cell-cell junctions between cells of the host. Tight cell-cell junctions, a cell-cell junction that seals cells together in an epithelium in a way that prevents even small molecules from leaking from one side of the sheet to the other.


name: DNA double-strand break processing involved in repair via single-strand annealing

description: The 5' to 3' exonucleolytic resection of the DNA at the site of the break to form a 3' single-strand DNA overhang that results in the repair of a double strand break via single-strand annealing.


name: response to water-immersion restraint stress

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of water immersion while being held immobile.


apiose metabolic process

description: The chemical reactions and pathways involving apiose, the branched tetrose 3-C-(hydroxymethyl)-D-glycero-tetrose.


description: Catalysis of the reaction: 2-oxoglutarate + UDP-2-acetamido-4-amino-2,4,6-trideoxy-D-glucose = L-glutamate + UDP-2-acetamido-4-dehydro-2,6-dideoxy-beta-D-glucose.


GABAergic neuron differentiation

description: The process in which a neuroblast acquires the specialized structural and functional features of a GABAergic neuron.


cobinamide kinase activity

description: Catalysis of the reaction: cobinamide + ATP = cobinamide phosphate + ADP. This reaction is the phosphorylation of the hydroxyl group of the 1-amino-2-propanol residue of cobinamide, in the presence of ATP, to form cobinamide phosphate.


regulation of muscle hypertrophy

description: Any process that modulates the frequency, rate or extent of muscle hypertrophy.


name: ATPase-coupled L-glutamine transmembrane transporter activity

description: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + glutamine(out) -> ADP + phosphate + glutamine(in).


3'-5' DNA/RNA helicase activity

description: Unwinding of a DNA/RNA duplex in the 3' to 5' direction, driven by ATP hydrolysis.


description: Catalysis of the reaction: 2-chloro-N-isopropylacetanilide + O2 + 2 H+ + NADH = 2-chloro-N-isopropylacetamide + catechol + NAD+.


cardioblast cell fate commitment

description: The process in which a cell becomes committed to becoming a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.


name: regulation of catecholamine metabolic process

description: Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving catecholamines.


histone H3R8 methyltransferase activity

description: Catalysis of the reaction: S-adenosyl-L-methionine + (histone H3)-arginine (position 8) = S-adenosyl-L-homocysteine + (histone H3-N-methyl-arginine (position 8). This reaction is the addition of a methyl group to the arginine residue at position 8 of histone H3.


name: benzyladenine UDP glycosyltransferase activity

description: Catalysis of the reaction: UDP-alpha-D-glucose + N-benzyladenine = H+ + N-benzyl-9-(alpha-D-glucosyl)adenine + UDP.


name: positive regulation of cardiac muscle cell differentiation

description: Any process that activates or increases the frequency, rate or extent of cardiac muscle cell differentiation.


name: antigen processing and presentation of exogenous peptide antigen via MHC class II

description: The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class II protein complex. The peptide antigen is typically, but not always, processed from a whole protein.


name: histone H4K12 methyltransferase activity

description: Catalysis of the reaction: S-adenosyl-L-methionine + histone H4 L-lysine (position 12) = S-adenosyl-L-homocysteine + histone H4 N6-methyl-L-lysine (position 12). This reaction is the addition of a methyl group to the lysine residue at position 12 of the histone H4 protein.


heme a metabolic process

description: The chemical reactions and pathways involving heme a, a derivative of heme found in cytochrome aa3.


steryl-beta-glucosidase activity

description: Catalysis of the reaction: cholesteryl-beta-D-glucoside + H2O = D-glucose + cholesterol.


regulation of actin filament severing

description: Any process that modulates the frequency, rate or extent of actin filament severing.


name: histamine-gated chloride channel activity

description: Enables the energy-independent facilitated diffusion of a chloride ion through a transmembrane channel that opens when bound to histamine.


name: nucleoside triphosphate diphosphatase activity

description: Catalysis of the reaction: a nucleoside triphosphate + H2O = a nucleotide + H+ + diphosphate.


hippocampus development

description: The progression of the hippocampus over time from its initial formation until its mature state.


embryonic axis specification

description: The establishment, maintenance and elaboration of a pattern along a line or a point in an embryo.


sperm DNA decondensation

description: Unwinding of the condensed nuclear chromatin of an inactive male pronucleus after fertilization.


name: positive regulation of heart rate by epinephrine

description: The process in which the secretion of epinephrine into the bloodstream or released from nerve endings increases the rate of heart muscle contraction.


description: Catalysis of the reaction: H2O + O2 + 2,5-dihydroxypyridine = formate + maleamate.


fluoren-9-ol dehydrogenase activity

description: Catalysis of the reaction: fluoren-9-ol + 2 NADP+ = fluoren-9-one + 2 NADPH + 2 H+.


name: regulation of twitch skeletal muscle contraction

description: Any process that modulates the frequency, rate or extent of twitch skeletal muscle contraction.


RNA polymerase V activity

description: Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template that contains an RNA polymerase V specific promoter to direct initiation and catalyses DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.


name: posterior lateral line neuromast support cell differentiation

description: The process in which a relatively unspecialized cell acquires specialized features of a posterior lateral line neuromast support cell. Support cells are non-sensory cells of the neuromast that extend between the sensory hair cells from the basement membrane to the apical surface; they are surrounded by mantle cells.


response to methionine

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methionine stimulus.


name: negative regulation of astrocyte chemotaxis

description: Any process that stops, prevents or reduces the frequency, rate or extent of astrocyte chemotaxis.


name: regulation of vasoconstriction by circulating norepinephrine

description: Any process that modulates the frequency, rate or extent of reductions in the diameter of blood vessels as a result of secretion of norepinephrine into the bloodstream.


T cell secretory granule organization

description: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a secretory granule in a T cell. A secretory granule is a small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion.


embryonic digestive tract morphogenesis

description: The process in which the anatomical structures of the digestive tract are generated and organized during embryonic development. The digestive tract is the anatomical structure through which food passes and is processed.


name: positive regulation of cartilage condensation

description: Any process that activates or increases the frequency, rate or extent of cartilage condensation.


lateral ventricle development

description: The process whose specific outcome is the progression of the lateral ventricles over time, from the formation to the mature structure. The two lateral ventricles are a cavity in each of the cerebral hemispheres derived from the cavity of the embryonic neural tube. They are separated from each other by the septum pellucidum, and each communicates with the third ventricle by the foramen of Monro, through which also the choroid plexuses of the lateral ventricles become continuous with that of the third ventricle.


name: alpha-linked polysaccharide catabolism to maltotriose

description: The breakdown of large alpha-linked polysaccharides by hydrolysis of (1->4)-alpha-D-glucosidic linkages to yield maltotriose.


phenanthrol sulfotransferase activity

description: Catalysis of the reaction: phenanthrol + X-SO3(-) = HX + phenanthrylsulfate.


phosphate ion homeostasis

description: Any process involved in the maintenance of an internal steady state of phosphate ions within an organism or cell.


name: protein N-linked glycosylation via tryptophan

description: The glycosylation of protein via peptidyl-tryptophan, 1'-glycosyl-L-tryptophan; results in the formation of an (S)-2-amino-3-(1-D-mannopyranosyloxy-1H-indol-3-yl)propanoic acid residue.


name: serine-type D-Ala-D-Ala carboxypeptidase activity

description: Catalysis of the reaction: (Ac)2-L-Lys-D-alanyl-D-alanine + H2O = (Ac)2-L-Lys-D-alanine + D-alanine.


name: oocyte microtubule cytoskeleton polarization

description: Establishment and maintenance of a specific axis of polarity of the oocyte microtubule network. The axis is set so that the minus and plus ends of the microtubules of the mid stage oocyte are positioned along the anterior cortex and at the posterior pole, respectively. An example of this is found in Drosophila melanogaster.


molybdopterin synthase activity

description: Catalysis of the conversion of precursor Z to molybdopterin, the final step in molybdopterin biosynthesis.


name: positive regulation of androstenedione secretion

description: Any process that activates or increases the frequency, rate or extent of androstenedione secretion.


zymosterol biosynthetic process

description: The chemical reactions and pathways resulting in the formation of zymosterol, (5alpha-cholesta-8,24-dien-3beta-ol).


regulation of meristem development

description: Any process that modulates the frequency, rate or extent of meristem development, the biological process whose specific outcome is the progression of the meristem over time, from its formation to the mature structure.


name: positive regulation of sprouting angiogenesis

description: Any process that activates or increases the frequency, rate or extent of sprouting angiogenesis.


negative regulation of heat generation

description: Any process that stops, prevents, or reduces the rate or extent of heat generation.


name: regulation of single-species biofilm formation

description: Any process that modulates the frequency, rate or extent of single-species biofilm formation.


negative regulation of hemopoiesis

description: Any process that stops, prevents or reduces the frequency, rate or extent of hemopoiesis.


interferon-alpha production

description: The appearance of interferon-alpha due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


leading edge cell fate determination

description: The process in which a cell becomes capable of differentiating autonomously into a leading edge cell regardless of its environment; upon determination, the cell fate cannot be reversed.


mRNA m(6)A methyltransferase activity

description: Catalysis of the reaction: an adenosine in mRNA + S-adenosyl-L-methionine = an N(6)-methyladenosine in mRNA + H+ + S-adenosyl-L-homocysteine. This activity is the methylation of adenines in mRNA with the consensus sequence RRACH, where R is a purine, and H is C, A, or U.


protein-heme linkage via 3'-L-histidine

description: The covalent linkage of heme and a protein via 3'-L-histidine (otherwise known as pi-heme-histidine, pros-heme-histidine).


Malpighian tubule bud morphogenesis

description: The morphogenetic process in which a bud forms from the embryonic hindgut tube to form the Malpighian tubule. A bud is a protrusion that forms from the tube by localized changes in cell shape and position.


endo-alpha-(2,8)-sialidase activity

description: Catalysis of the endohydrolysis of (2->8)-alpha-sialosyl linkages in oligo- or poly(sialic) acids.


retinoic acid catabolic process

description: The chemical reactions and pathways resulting in the breakdown of retinoic acid, one of the three components that makes up vitamin A.


DNA excision

description: The removal of a section of DNA from a larger DNA molecule by the making of dual incisions that flank the section to be excised.


sinoatrial node cell differentiation

description: The process in which a relatively unspecialized cell acquires specialized features of a sinoatrial (SA) node cell. SA node cells are pacemaker cells that are found in the sinoatrial node.


sphingomyelin metabolic process

description: The chemical reactions and pathways involving sphingomyelin, N-acyl-4-sphingenyl-1-O-phosphorylcholine, any of a class of phospholipids in which the amino group of sphingosine is in amide linkage with one of several fatty acids, while the terminal hydroxyl group of sphingosine is esterified to phosphorylcholine.


kappa-carrageenase activity

description: Catalysis of the endohydrolysis of 1,4-beta-D-linkages between D-galactose 4-sulfate and 3,6-anhydro-D-galactose in kappa-carrageenans.


description: The chemical reactions and pathways involving 5,6,7,8-tetrahydromethanopterin.


name: lysine biosynthetic process via diaminopimelate and L-2-acetamido-6-oxoheptanedioate

description: The chemical reactions and pathways resulting in the formation of lysine, via the intermediates diaminopimelate and L-2-acetamido-6-oxoheptanedioate; in this pathway tetrahydrodipicolinate is converted to meso-diaminopimelate in four enzymatic steps.


epinephrine binding

description: Binding to epinephrine, a hormone produced by the medulla of the adrenal glands that increases heart activity, improves the power and prolongs the action of muscles, and increases the rate and depth of breathing. It is synthesized by the methylation of norepinephrine.


lactase activity

description: Catalysis of the reaction: lactose + H2O = D-glucose + D-galactose.


name: symbiont-mediated suppression of host interferon-mediated signaling pathway

description: Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of interferon-mediated signaling in the host organism.


secondary heart field specification

description: The process that results in the delineation of a specific region of the lateral mesoderm into the area which will form the majority of the mesodermal component of the right ventricle, arterial pole (outflow tract) and venous pole (inflow tract).


name: activation of prostate induction by androgen receptor signaling pathway

description: The series of molecular signals initiated by androgen binding to its receptor in the urogenital sinus mesenchyme that initiates prostate induction. Prostate induction is the close range interaction of the urogenital sinus mesenchyme and the urogenital sinus epithelium that causes the cells of the urogenital sinus epithelium to change their fates and specify the development of the prostate gland.


name: prostaglandin transmembrane transporter activity

description: Enables the transfer of prostaglandins from one side of a membrane to the other. A prostaglandin is any of a group of biologically active metabolites which contain a cyclopentane ring due to the formation of a bond between two carbons of a fatty acid. They have a wide range of biological activities.


name: positive regulation of inhibin secretion

description: Any process that activates or increases the frequency, rate or extent of the regulated release of inhibin from a cell.