name: symbiont-mediated suppression of host NF-kappaB cascade

description: A process in which a symbiont interferes with, inhibits or disrupts an NF-kappaB-mediated signaling cascade in its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.


response to (R)-carnitine

category: biolink:BiologicalProcess biolink:Occurrent biolink:OntologyClass biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an (R)-carnitine stimulus.


name: response to pulsatile fluid shear stress

description: Any response to fluid shear stress where the fluid is flowing across a solid surface with periodic variations. For example, the endothelium in straight parts of the artery tree is subjected to pulsatile shear stress with a significant forward direction, which is believed to be an important physiological stimulus enhancing vessel compliance and conferring anti-thrombotic, anti-adhesive, and anti-inflammatory effects.


category: biolink:MolecularActivity biolink:Occurrent biolink:OntologyClass biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: Catalysis of 5-taurinomethyluridine in tRNA + a [protein]-S-sulfanylcysteine + ATP + a reduced electron acceptor = a 5-taurinomethyl-2-thiouridine in tRNA + a [protein]-L-cysteine + AMP + an oxidized electron acceptor + diphosphate + H+.


(S)-6-hydroxynicotine oxidase activity

description: Catalysis of the reaction: (S)-6-hydroxynicotine + H2O + O2 = 6-hydroxypseudooxynicotine + H2O2.


cell fate determination

description: The cellular developmental process involved in cell fate commitment that occurs after cell fate specification, in which a cell is irreversibly committed to a cellular developmental fate which is heritable on cell division.


category: biolink:Pathway biolink:OntologyClass biolink:BiologicalProcess biolink:Occurrent biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: The series of molecular signals initiated by erythropoietin (EPO) binding to the erythropoietin receptor (EPO-R) on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.


name: positive regulation of glial cell differentiation

description: Any process that activates or increases the frequency, rate or extent of glia cell differentiation.


capsanthin biosynthetic process

description: The chemical reactions and pathways resulting in the formation of capsanthin.


high-affinity IgM receptor activity

description: Combining with high affinity with an immunoglobulin of an IgM isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


homomethionine biosynthetic process

description: The chemical reactions and pathways resulting in the formation of homomethionine, a non-protein amino acid synthesized from methionine via chain elongation.


description: The process of coupling alanine to alanyl-tRNA in a mitochondrion, catalyzed by alanyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.


name: negative regulation of receptor signaling pathway via STAT

description: Any process that stops, prevents or reduces the frequency, rate or extent of receptor signaling via STAT.


description: Catalysis of the reaction: N-acetyl-D-glucosaminyldiphosphoundecaprenol + UDP-N-acetyl-D-mannosamine = N-acetyl-beta-D-mannosaminyl-1,4-N-acetyl-D-glucosaminyldiphosphoundecaprenol + UDP.


name: chromosomal 5-methylcytosine DNA demethylation, oxidative deamination pathway

description: An epigenetic cytosine DNA demethylation pathway that includes a deamination step to produce either a thymine (T), or a 5-hydroxymethyluracil (5hmU), if the 5meC had first been converted to 5hmC. A DNA glycosylase (e. g. TDG) recognizes the T mispaired with a G or the 5hmC and excises the modified base to initiate its replacement with unmethylated cytosine through base excision repair.


regulation of NK T cell proliferation

description: Any process that modulates the frequency, rate or extent of natural killer T cell proliferation.


name: negative regulation of glycogen synthase activity, transferring glucose-1-phosphate

description: Any process that stops, prevents or reduces the frequency, rate or extent of glycogen synthase activity, transferring glucose-1-phosphate.


name: constitutive protein ectodomain proteolysis

description: The proteolytic cleavage of transmembrane proteins and release of their ectodomain that occurs constantly, regardless of environmental conditions or demands.


ureidoglycolate hydrolase activity

description: Catalysis of the reaction: (S)-ureidoglycolate + H2O + 2 H+ = CO2 + glyoxylate + 2 NH4.


mineralocorticoid biosynthetic process

description: The chemical reactions and pathways resulting in the formation of mineralocorticoids, hormonal C21 corticosteroids synthesized from cholesterol.


cellular response to cobalamin

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cobalamin (vitamin B12) stimulus.


description: Catalysis of the reaction: 1,2-dihydroxynaphthalene-6-sulfonate + O2 = H+ + (Z)-4-(2-hydroxy-5-sulfonatophenyl)-2-oxo-3-butenoate.


mesonephros development

description: The process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. In mammals, the mesonephros is the second of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the mesonephros will form the mature kidney.


aspartate ammonia-lyase activity

description: Catalysis of the reaction: L-aspartate = fumarate + NH3.


cerebellar granule cell differentiation

description: The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature cerebellar granule cell. Differentiation includes the processes involved in commitment of a neuroblast to a granule cell fate. A granule cell is a glutamatergic interneuron found in the cerebellar cortex.


name: positive regulation of myeloid progenitor cell differentiation

description: Any process that activates or increases the frequency, rate or extent of myeloid progenitor cell differentiation.


exo-alpha-(2->3)-sialidase activity

description: Catalysis of the hydrolysis of alpha-(2->3)-glycosidic linkages of terminal sialic residues in substrates.


name: atrazine catabolic process to isopropylamine

description: The chemical reactions and pathways resulting in the breakdown of atrazine, a triazine ring-containing herbicide, into isopropylamine.


name: 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate metabolic process

description: The chemical reactions and pathways involving 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate.


D-ribose 5-phosphate metabolic process

description: The chemical reactions and pathways involving D-ribose 5-phosphate.


description: Catalysis of the reaction: UDP-alpha-D-glucose + coniferyl aldehyde = H+ + coniferaldehyde glucoside + UDP.


reproductive blastospore formation

description: The formation of a spore following the marked enlargement of part of a cell before separation by a septum. Blastospores are a type of asexual spore found in some fungi, most notably the class Glomeromycota.


regulation of bone development

description: Any process that modulates the frequency, rate or extent of bone development.


name: regulation of programmed necrotic cell death

description: Any process that modulates the frequency, rate or extent of programmed necrotic cell death.


colanic acid metabolic process

description: The chemical reactions and pathways involving colanic acid, a capsular bacterial polysaccharide composed of glucose, galactose, fucose and glucuronic acid residues.


description: Catalysis of the reaction: 1-alkenylglycerophosphoethanolamine + acyl-CoA = 1-alkenyl-2-acyl-glycerophosphoethanolamine + CoA.


neuroinflammatory response

description: The immediate defensive reaction by neural vertebrate tissue to infection or injury caused by chemical or physical agents.


negative regulation of gastric emptying

description: Any process that decreases the frequency, rate or extent of any gastric emptying process, the process in which the liquid and liquid-suspended solid contents of the stomach exit through the pylorus into the duodenum.


description: Catalysis of the reaction: (3E)-4-(2-carboxyphenyl)-2-oxobut-3-enoate = 2-carboxybenzaldehyde + pyruvate.


arogenate dehydratase activity

description: Catalysis of the reaction: L-arogenate = L-phenylalanine + H2O + CO2.


mitochondria-nucleus signaling pathway

description: The series of molecular signals that forms a pathway of communication from the mitochondria to the nucleus and initiates cellular changes in response to changes in mitochondrial function.


primary sex determination, germ-line

description: The transmission of information about sexual status, from the initial general determination, to signals specific to the germ-line.


DCT cell fate commitment

description: The process in which the developmental fate of a cell becomes restricted such that it will develop into a distal convoluted tubule cell.


trachea submucosa development

description: The progression of the trachea submucosa over time from its formation to the mature structure. The trachea submucosa is made up of the glands and elastic tissue that lie under the mucosa in the trachea.


name: positive regulation of myoblast differentiation

description: Any process that activates or increases the frequency, rate or extent of myoblast differentiation. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.


heart valve development

description: The progression of a heart valve over time, from its formation to the mature structure. A heart valve is a structure that restricts the flow of blood to different regions of the heart and forms from an endocardial cushion.


description: Catalysis of the reaction: 3-hydroxybenzyl alcohol + NADP+ = 3-hydroxybenzaldehyde + H+ + NADPH.


description: Catalysis of the reaction: heteroglycan + GDP-mannose = alpha-D-mannosylheteroglycan + GDP.


description: Catalysis of the reaction: NADP+ + scytalone = NADPH + H+ + 1,3,6,8-naphthalenetetrol.


name: U6 snRNA 2'-O-ribose methyltransferase activity

description: Catalysis of the reaction: S-adenosyl-L-methionine + U6 snRNA = S-adenosyl-L-homocysteine + U6 containing a 3'-terminal 2'-O-methylnucleotide + H+.


description: The chemical reactions and pathways resulting in the formation of tetrahydrofolylpolyglutamate, a folate derivative comprising tetrahydrofolate attached to a chain of glutamate residues.


response to kainic acid

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a kainic acid stimulus.


name: regulation of gibberellic acid mediated signaling pathway

description: Any process that modulates the frequency, rate or extent of gibberellic acid mediated signaling.


name: regulation of skeletal muscle hypertrophy

description: Any process that modulates the frequency, rate or extent of skeletal muscle hypertrophy.


meiotic anaphase I

description: The cell cycle phase during which chromosomes separate and migrate towards the poles of the spindle the as part of meiosis I.


linoleate 8R-lipoxygenase activity

description: Catalysis of the reaction: O2 + linoleate = (8R,9Z,12Z)-8-hydroperoxyoctadeca-9,12-dienoate.


phosphatidylcholine desaturase activity

description: Catalysis of the reaction: An oleoyl-[glycerolipid] + 2 ferrocytochrome b5 + O2 + 2 H+ = a linoleoyl-[glycerolipid] + 2 ferricytochrome b5 + 2 H2O.


hepatocyte growth factor production

description: The appearance of hepatocyte growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


name: L-threonine catabolic process to glycine

description: The chemical reactions and pathways resulting in the breakdown of L-threonine (the L-enantiomer of 2-amino-3-hydroxybutyric acid) to form to form 2-amino-3-oxobutanoate, which is subsequently converted to glycine.


name: oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity

description: Catalysis of the removal oxidized pyrimidine bases by cleaving the N-C1' glycosidic bond between the oxidized pyrimidine and the deoxyribose sugar. The reaction involves formation of a covalent enzyme-pyrimidine base intermediate. Release of the enzyme and free base by a beta-elimination or a beta, gamma-elimination mechanism results in the cleavage of the DNA backbone 3' of the apyrimidinic (AP) site.


regulation of embryonic development

description: Any process that modulates the frequency, rate or extent of embryonic development.


name: glutathione derivative catabolic process

description: The chemical reactions and pathways resulting in the breakdown of glutathione derivative.


name: envenomation resulting in vasodilation in another organism

description: A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with resultant vasodilation of blood vessels, usually causing a reduction in blood pressure, in the bitten/stung organism.


interphase mitotic telomere clustering

description: The process whereby the mitotic telomeres are gathered together during, or prior to, attachment to the nuclear envelope.


AUU codon-amino acid adaptor activity

description: A triplet codon-amino acid adaptor activity that recognizes an AUU codon.


name: formation of specialized structure for nutrient acquisition

description: The assembly of a symbiotic cellular or anatomical structure for the purpose of obtaining nutrients from its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.


positive regulation of heart growth

description: Any process that increases the rate or extent of heart growth. Heart growth is the increase in size or mass of the heart.


pronuclear envelope synthesis

description: Synthesis and ordering of the envelope of pronuclei.


name: extraction of mislocalized protein from mitochondrial outer membrane

description: The removal of a mislocalized protein from the mitochondrial outer membrane.


name: central tolerance induction to nonself antigen

description: Tolerance induction to nonself antigens in the central lymphoid organs.


xanthine DNA N-glycosylase activity

description: DNA N-glycosylase activity acting on deaminated guanine (xanthine).


meiosis II cell cycle phase

description: A meiotic cell cycle phase that occurs after meiosis I (the first meiotic nuclear division).


ochratoxin A metabolic process

description: The chemical reactions and pathways involving ochratoxin A.


name: anterior lateral line neuromast cupula development

description: The process whose specific outcome is the progression of the anterior lateral line neuromast cupula over time, from its formation to the mature structure. The cupula is secreted by mantle cells and the ciliary bundles of all of the hair cells of the neuromast are embedded in it. The cupula provides a mechanical linkage between the hair cells and the external hydrodynamic environment. The cupula of superficial neuromasts grows continuously, while the height of the cupula of canal neuromasts is limited by canal diameter.


name: alpha-ketoglutarate transmembrane transporter activity

description: Enables the transfer of alpha-ketoglutarate from one side of a membrane to the other. Alpha-ketoglutarate (or oxoglutarate) is a compound with important roles in carbohydrate and amino acid metabolism, especially in transamination reactions and as a component of the TCA cycle.


strombine dehydrogenase activity

description: Catalysis of the reaction: N-(carboxymethyl)-D-alanine + H2O + NAD+ = glycine + H+ + NADH + pyruvate.


organic phosphonate metabolic process

description: The chemical reactions and pathways involving phosphonates, any organic compounds containing one or more C-PO(OH)2 or C-PO(OR)2 (with R=alkyl, aryl) groups. Metabolism of phosphonic acid itself, an inorganic compound without the biochemically relevant C-P bond, is not included.


description: Catalysis of the hydrolysis of (1->4)-beta-D-glucosidic linkages in cellulose and cellotetraose, releasing cellobiose from the non-reducing ends of the chains.


mannogen biosynthetic process

description: The chemical reactions and pathways resulting in the formation of mannogen, a mannose-containing polysaccharide that is a major energy reserve in Leishmania.


regulation of cartilage condensation

description: Any process that modulates the frequency, rate or extent of cartilage condensation.


phytochromobilin metabolic process

description: The chemical reactions and pathways involving phytochromobilin, the linear tetrapyrrole chromophore required for plant phytochrome photoactivity.


tooth placode formation

description: The developmental process in which the tooth placode forms. A tooth placode is a thickening of the ectoderm that will give rise to the tooth bud.


interleukin-18 production

description: The appearance of interleukin-18 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


name: T cell tolerance induction in mucosal-associated lymphoid tissue

description: Tolerance induction taking place in the mucosal-associated lymphoid tissue (MALT) mediated by T cells.


name: 2-desacetyl-2-hydroxyethyl bacteriochlorophyllide a dehydrogenase activity

description: Catalysis of the reaction: 2-desacetyl-2-hydroxyethyl bacteriochlorophyllide a = bacteriochlorophyllide a + 2 H+.


2-oxopent-4-enoate hydratase activity

description: Catalysis of the reaction: 4-hydroxy-2-oxopentanoate = 2-oxopent-4-enoate + H2O.


description: Catalysis of the reaction: quercetin-3-glucoside + UDP-alpha-D-glucose(2-) = quercetin-3-gentiobioside + UDP.


name: bundle of His cell-Purkinje myocyte adhesion involved in cell communication

description: The attachment of a bundle of His cell to a Purkinje myocyte via adhesion molecules that results in the cells being juxtaposed so that they can communicate.


'de novo' AMP biosynthetic process

description: The chemical reactions and pathways resulting in the formation of adenosine monophosphate (AMP) from inosine 5'-monophosphate (IMP).


description: Catalysis of the reaction: 5-oxopent-3-ene-1,2,5-tricarboxylate = 2-oxohept-3-enedioate + CO2.


smooth muscle contraction

description: A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. Smooth muscle differs from striated muscle in the much higher actin/myosin ratio, the absence of conspicuous sarcomeres and the ability to contract to a much smaller fraction of its resting length.


name: generation of mature 3'-end of 5S rRNA generated by RNA polymerase III

description: The removal of extra uridine residues from the 3' end of a 5S pre-rRNA generated by transcription by RNA polymerase III to generate the mature 3'-end.


tRNA N2-guanine methylation

description: The process whereby a guanine in a tRNA is methylated at the N2 position of guanine.


13-prostaglandin reductase activity

description: Catalysis of the reaction: 15-keto-prostaglandin + NAD(P)H + H+ -> 13,14-dihydro-15-keto-prostaglandin + NAD(P)+. This reaction is the reduction of 15-keto-prostaglandin.


name: NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity

description: Catalysis of the transfer of ADP-ribose groups to the glutamate-18 residue of histone H2B (or an equivalent residue).


olfactory receptor activity

description: Combining with an odorant and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity in response to detection of smell.


fructosyl-amino acid oxidase activity

description: Catalysis of the reaction: fructosyl-amino acid + O2 = corresponding amino acid + glucosone + H2O2.


name: regulation of cell proliferation involved in kidney development

description: Any process that modulates the frequency, rate or extent of cell proliferation involved in kidney development.


name: amyloid precursor protein catabolic process

description: The chemical reactions and pathways resulting in the breakdown of amyloid precursor protein (APP), the precursor of amyloid-beta, a glycoprotein associated with Alzheimer's disease.


name: red or far-red light photoreceptor activity

description: The function of absorbing and responding to electromagnetic radiation with a wavelength of approximately 660-730nm. The response may involve a change in conformation.


alpha-copaene synthase activity

description: Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = alpha-copaene + diphosphoric acid.


name: mesoderm migration involved in gastrulation

description: The migration of mesodermal cells during gastrulation to help establish the multilayered body plan of the organism.


name: regulation of cardiac muscle tissue regeneration

description: Any process that modulates the frequency, rate or extent of cardiac muscle tissue regeneration.


ABC-type tungstate transporter activity

description: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + tungstate(in) = ADP + phosphate + tungstate(out).


lateral mesodermal cell differentiation

description: The process in which a relatively unspecialized cell acquires the specialized features of a lateral mesoderm cell.


name: regulation of polysaccharide metabolic process

description: Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving polysaccharides.


trigeminal nerve maturation

description: A developmental process, independent of morphogenetic (shape) change, that is required for the trigeminal nerve to attain its fully functional state. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae.


amine catabolic process

description: The chemical reactions and pathways resulting in the breakdown of any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom.


name: fusion of virus membrane with host plasma membrane

description: Fusion of a viral membrane with the host cell membrane during viral entry. Results in release of the virion contents into the cytoplasm.


name: negative regulation of testicular blood vessel morphogenesis

description: Any process that stops, prevents, or reduces the frequency, rate or extent of blood vessel morphogenesis in the testicle.


nociceptin receptor activity

description: Combining with the peptide nociceptin, and transmitting the signal across the membrane by activating an associated G-protein.


name: inositol pentakisphosphate 2-kinase activity

description: Catalysis of the reaction: 1D-myo-inositol 1,3,4,5,6-pentakisphosphate + ATP = 1D-myo-inositol hexakisphosphate + ADP + 2 H+.


cellular response to ionomycin

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ionomycin stimulus.


name: RNA 5'-gamma-phosphate methyltransferase activity

description: Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the 5'-gamma-phosphate in an RNA molecule.


name: positive regulation of blood vessel endothelial cell migration

description: Any process that activates or increases the frequency, rate or extent of the migration of the endothelial cells of blood vessels.


pollen-pistil interaction

description: The interaction between a pollen grain and pistil.


sensory organ boundary specification

description: The process in which boundaries between a sensory organ and the surrounding tissue are established and maintained.


rhamnogalacturonan endolyase activity

description: Catalysis of the reaction: H2O + a rhamnogalacturonan type I = [rhamnogalacturonan I oligosaccharide]-alpha-L-rhamnose + 4-deoxy-4,5-unsaturated D-galactopyranosyluronate-[rhamnogalacturonan I oligosaccharide].


regulation of T cell differentiation

description: Any process that modulates the frequency, rate or extent of T cell differentiation.


name: mRNA splicing, via endonucleolytic cleavage and ligation

description: Splicing of mRNA substrates via recognition of the folded RNA structure that brings the 5' and 3' splice sites into proximity and cleavage of the RNA at both the 3' and 5' splice sites by an endonucleolytic mechanism, followed by ligation of the exons.


teichoic acid biosynthetic process

description: The chemical reactions and pathways resulting in the formation of teichoic acid, any polymer occurring in the cell wall, membrane or capsule of Gram-positive bacteria and containing chains of glycerol phosphate or ribitol phosphate residues.


swim bladder morphogenesis

description: The process in which the anatomical structure of the swim bladder is generated and organized. The swim bladder is used by some fishes to maintain buoyancy and may function in addition as a sound producing organ, a sound receptor, and a respiratory organ.


description: Binding to beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-D-Glc.


D-octopine dehydrogenase activity

description: Catalysis of the reaction: N2-(D-1-carboxyethyl)-L-arginine + NAD+ + H2O = L-arginine + pyruvate + NADH.


lipoprotein catabolic process

description: The chemical reactions and pathways resulting in the breakdown of any conjugated, water-soluble protein in which the covalently attached nonprotein group consists of a lipid or lipids.


UDP catabolic process

description: The chemical reactions and pathways resulting in the breakdown of UDP, uridine (5'-)diphosphate.


name: renal vasodilation of the peripheral vascular system involved in regulation of systemic arterial blood pressure

description: The renal process that modulates the force with which blood travels through the circulatory system, by vasodilation of the peripheral vascular system.


transketolase activity

description: Catalysis of the reversible transfer of a 2-carbon ketol group (CH2OH-CO-) from a ketose phosphate donor to an aldose phosphate acceptor.


response to leukemia inhibitory factor

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leukemia inhibitory factor stimulus.


embryonic pelvic fin morphogenesis

description: The process, occurring in the embryo, by which the anatomical structures of the pelvic fin are generated and organized. The pelvic fins are bilaterally paired fins mounted in a ventral-lateral position on most fish. These fins are used primarily for lateral mobility and propulsion.


name: regulation of adenine biosynthetic process

description: Any process that modulates the frequency, rate or extent of an adenine biosynthetic process.


plastid fission

description: The creation of two or more plastids by division of one plastid. A plastid is any member of a family of organelles found in the cytoplasm of plants and some protists, which are membrane-bounded and contain DNA.


name: cellular response to electrical stimulus

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electrical stimulus.


neural fold folding

description: The process of folding the neuroepithelium around the medial hinge point to create the neural elevations, and around the lateral hinge points to produce convergence of the folds.


name: cytoplasmic actin-based contraction involved in forward cell motility

description: The actin filament-based movement by which cytoplasmic actin filaments slide past one another resulting in a contraction that propels the cell in the direction that has been defined as the front of the cell.


luteal cell differentiation

description: The process in which a relatively unspecialized cell acquires the specialized features of a luteal cell. Large luteal cells develop from granulosa cells. Small luteal cells develop from theca cells.


description: The chemical reactions and pathways resulting in the breakdown of 2-chloro-N-isopropylacetanilide, an acylanide herbicide widely used to protect corn, onion, cabbage, rose bushes, and ornamental plants.


name: histone arginine N-methyltransferase activity

description: Catalysis of the reaction: S-adenosyl-L-methionine + (histone)-arginine = S-adenosyl-L-homocysteine + (histone)-N-methyl-arginine.


name: positive regulation of antigen processing and presentation of polysaccharide antigen via MHC class II

description: Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of polysaccharide antigen via MHC class II.


name: peptide lactyltransferase (CoA-dependent) activity

description: Catalysis of the reaction: (L-lysyl-[protein] + lactoyl-CoA = CoA + H+ + N(6)-lactoyl-L-lysyl-[protein].


myosin light chain kinase activity

description: Catalysis of the reaction: ATP + myosin-light-chain = ADP + myosin-light-chain phosphate.


cellular response to chloramphenicol

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chloramphenicol stimulus.


description: Catalysis of the reaction: 30-hydroxy-beta-amyrin + O2 + NADPH + H+ = 11alpha,30-dihydroxy-beta-amyrin + H2O + NADP.


name: eosinophil activation involved in immune response

description: The change in morphology and behavior of a eosinophil resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response.


lactosylceramide biosynthetic process

description: The chemical reactions and pathways resulting in the formation of lactosylceramides, Gal-beta-(1->4)-Glc-beta(1->1') ceramides, any compound formed by the replacement of the glycosidic C1 hydroxyl group of lactose by a ceramide group. They are the precursors of both gangliosides and globosides.


name: positive regulation of copper ion transmembrane transport

description: Any process that activates or increases the frequency, rate or extent of copper ion transmembrane transport.


description: Catalysis of the reaction: O2 + 3-hydroxy-1H-quinolin-4-one = carbon monoxide + N-formylanthranilate.


name: anaerobic ethylbenzene catabolic process

description: The chemical reactions and pathways resulting in the breakdown of ethylbenzene, a benzene derivative with an ethyl group attached to the ring, which occurs in the absence of oxygen.


L-carnitine CoA-transferase activity

description: Catalysis of the reactions: (E)-4-(trimethylammonio)but-2-enoyl-CoA + L-carnitine = (E)-4-(trimethylammonio)but-2-enoate + L-carnitinyl-CoA and 4-trimethylammoniobutanoyl-CoA + L-carnitine = 4-trimethylammoniobutanoate + L-carnitinyl-CoA.


response to food

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a food stimulus; food is anything which, when taken into the body, serves to nourish or build up the tissues or to supply body heat.


type I interferon production

description: The appearance of type I interferon due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.


name: cellular response to 3,3',5-triiodo-L-thyronine

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 3,3',5-triiodo-L-thyronine stimulus.


blastocyst development

description: The process whose specific outcome is the progression of the blastocyst over time, from its formation to the mature structure. The mammalian blastocyst is a hollow ball of cells containing two cell types, the inner cell mass and the trophectoderm.


ADP-riboxanase activity

description: Catalysis of the reaction: L-arginyl-[protein] + NAD+ = ADP-riboxanated L-argininyl-[protein] + H+ + NH4(+) + nicotinamide.


name: proton-transporting ATP synthase complex assembly

description: The aggregation, arrangement and bonding together of a proton-transporting ATP synthase (also known as F-type ATPase), a two-sector ATPase found in the inner membrane of mitochondria and chloroplasts, and in bacterial plasma membranes.


morphogenesis of a polarized epithelium

description: The morphogenetic process in which the anatomical structures of a polarized epithelium are generated and organized. A polarized epithelium is an epithelium where the epithelial sheet is oriented with respect to the planar axis.


description: Catalysis of the reaction: 5,10-methenyl-5,6,7,8-tetrahydromethanopterin + H2O = N(5)-formyl-5,6,7,8-tetrahydromethanopterin + H+.


protein trimerization

description: The formation of a protein trimer, a macromolecular structure consisting of three noncovalently associated identical or nonidentical subunits.


ribulokinase activity

description: Catalysis of the reaction: ATP + L(or D)-ribulose = ADP + L(or D)-ribulose 5-phosphate.


name: ATP-dependent diacylglycerol kinase activity

description: Catalysis of the reaction: a 1,2-diacyl-sn-glycerol + ATP = a 1,2-diacyl-sn-glycero-3-phosphate + ADP + H+.


description: Catalysis of the reaction: 9,15,9'-tricis-zeta-carotene = 9,9'-dicis-zeta-carotene.


name: ecdysis, collagen and cuticulin-based cuticle

description: The shedding of the old collagen and cuticulin-based cuticle fragments during the molting cycle. Examples of this process are found in invertebrates.


name: positive regulation of miRNA metabolic process

description: Any process that activates or increases the frequency, rate or extent of miRNA metabolic process.


mRNA cap binding complex binding

description: Binding to a mRNA cap binding complex.


regulation of lipid storage

description: Any process that modulates the rate, frequency or extent of lipid storage. Lipid storage is the accumulation and maintenance in cells or tissues of lipids, compounds soluble in organic solvents but insoluble or sparingly soluble in aqueous solvents. Lipid reserves can be accumulated during early developmental stages for mobilization and utilization at later stages of development.


name: amino acid catabolic process to alcohol via Ehrlich pathway

description: The chemical reactions and pathways involving the catabolism of amino acids to produce alcohols with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of alcohols, often collectively referred to as fusel alcohols. Depending on the redox state of the cells, carboxylic acid derivatives may be produced instead of alcohols.


name: regulation of single-species biofilm formation in or on host organism

description: Any process that modulates the frequency, rate or extent of single-species biofilm formation in or on host organism.


name: L-arabinose catabolic process to 2-oxoglutarate

description: The chemical reactions and pathways resulting in the breakdown of L-arabinose into other compounds, including 2-oxoglutarate.


name: positive regulation of dopamine secretion

description: Any process that activates or increases the frequency, rate or extent of the regulated release of dopamine.


rhombomere morphogenesis

description: The process in which the anatomical structure of the rhombomere is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates.


inductive cell migration

description: Migration of a cell in a multicellular organism that, having changed its location, is required to induce normal properties in one or more cells at its new location. An example of this would be the distal tip cells of Caenorhabditis elegans.


brassinolide synthase activity

description: Catalysis of the reaction: H+ + castasterone + NADPH + O2 = brassinolide + NADP + H2O.


name: salicin transmembrane transporter activity

description: Enables the transfer of salicin (saligenin-beta-D-glucopyranoside), a glucoside of o-hydroxybenzylalcohol, from one side of a membrane to the other.


phenanthrene 1,2-monooxygenase activity

description: Catalysis of the reaction: phenanthrene + O2 + NADH + H+ = H2O + NAD+ + phenanthrene-1,2-oxide.


protein localization to spore cell wall

description: A process in which a protein is transported, tethered to or otherwise maintained in a spore cell wall.


name: neurotransmitter receptor activity involved in regulation of presynaptic cytosolic calcium ion concentration

description: Any neurotransmitter receptor activity that is involved in regulating the concentration of calcium in the presynaptic cytosol.


pH-gated chloride channel activity

description: A gated channel activity that enables the transmembrane transfer of a chloride ion by a channel that opens in response to a change in pH.


plasmacytoid dendritic cell chemotaxis

description: The movement of a plasmacytoid dendritic cell in response to an external stimulus.


regulation of thymocyte aggregation

description: Any process that modulates the frequency, rate or extent of thymocyte aggregation.


flavanone 4-reductase activity

description: Catalysis of the reaction: (2S)-flavan-4-ol + NADP+ = (2S)-flavanone + NADPH.


name: regulation of anthocyanin catabolic process

description: Any process that modulates the frequency, rate or extent of anthocyanin catabolic process.


name: delphinidin 3-O-glucoside 5-O-glucosyltransferase (vanilloyl-glucose dependent) activity

description: Catalysis of the reaction: delphinidin 3-O-beta-D-glucoside + 1-O-vanilloyl-beta-D-glucose = delphinidin 3,7-di O-beta-D-glucoside + vanillate + H+.


name: membrane macromolecule biosynthetic process

description: The chemical reactions and pathways resulting in the formation of a macromolecule destined to form part of a membrane in a cell.


name: NAD-dependent protein lipoamidase activity

description: Catalysis of the reaction: (R)-N6-lipoyl-L-lysyl-[protein] + H2O + NAD+ = 2''-O-lipoyl-ADP-D-ribose + L-lysyl-[protein] + nicotinamide.


D-allose metabolic process

description: The chemical reactions and pathways involving D-allose, the D-enantiomer of allo-hexose, an aldohexose similar to glucose.


name: neural crest-derived cardiac fibroblast cell fate commitment

description: The commitment of neural crest cells to a cardiac fibroblast fate and their capacity to differentiate into cardiac fibroblast cells. A cardiac fibroblast is a connective tissue cell in the heart which secretes an extracellular matrix rich in collagen and other macromolecules.


response to anticoagulant

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an anticoagulant stimulus.


regulation of activin secretion

description: Any process that modulates the frequency, rate or extent of the regulated release of activin from a cell.


name: cell-cell signaling involved in kidney development

description: Any process that mediates the transfer of information from one cell to another and contributes to the progression of the kidney over time, from its formation to the mature organ.


thick ascending limb development

description: The process whose specific outcome is the progression of the thick ascending limb over time, from its formation to the mature structure. The thick ascending limb is the last part of the loop of Henle. Its thick, mitochondria-rich epithelium characterizes the outer medulla, and is responsible for very avid active salt transport. At the macula densa, the thick ascending limb connects to the distal convoluted tubule.


name: detection of electrical stimulus involved in magnetoreception

description: The series of events that contribute to magnetoception in which an electrical stimulus is received and converted into a molecular signal. The stimulus is in the form of an induced electric field resulting from movement in a magnetic field.


ganglion morphogenesis

description: The process in which the anatomical structures of ganglion are generated and organized.


name: retrograde trans-synaptic signaling by nitric oxide

description: Cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by nitric oxide.


name: positive regulation of Ras protein signal transduction

description: Any process that activates or increases the frequency, rate or extent of Ras protein signal transduction.


name: symbiont-mediated perturbation of host Rho signal transduction

description: A process in which a symbiont alters a Rho protein family-mediated signal transduction pathway in its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.


peptidyl-threonine O-acetylation

description: The acetylation of peptidyl-threonine to form peptidyl-O-acetyl-L-threonine.


response to pH

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus. pH is a measure of the acidity or basicity of an aqueous solution.


deacetylisoipecoside synthase activity

description: Catalysis of the reaction: deacetylisoipecoside + H2O = dopamine + secologanin.


peptidyl-lysine demalonylation

description: The process of removing a malonyl group (CO-CH2-CO) from an malonylated lysine residue in a peptide or protein.


detoxification of copper ion

description: Any process that reduces or removes the toxicity of copper ion. These include transport of copper away from sensitive areas and to compartments or complexes whose purpose is sequestration of copper ion.


determination of wing disc primordium

description: Allocation of embryonic cells to the wing disc founder populations, groups of cells that are committed to contribute to the formation of a wing imaginal disc.


Golgi apparatus mannose trimming

description: Any protein alpha-1,2-demannosylation that takes place in the Golgi apparatus.


name: L-2-hydroxycarboxylate dehydrogenase (NAD+) activity

description: Catalysis of the reaction: NAD(1-) + a (2S)-2-hydroxycarboxylate = NADH(2-) + H+ + a 2-oxo carboxylate.


oxaloacetate decarboxylase activity

description: Catalysis of the reaction: oxaloacetate = pyruvate + CO2.


name: formation of structure involved in a symbiotic process

description: The progression of an organism from an initial condition to a later condition, occurring when the organism is in a symbiotic interaction.


description: Catalysis of the reaction: L-glutamate + acetyl-CoA = N-acetyl-L-glutamate + CoA + H+.


name: positive regulation of axial mesodermal cell fate determination

description: Any process that activates or increases the frequency, rate or extent of axial mesoderm cell fate determination.


dTDP-glucose 4,6-dehydratase activity

description: Catalysis of the reaction: dTDP-glucose = dTDP-4-dehydro-6-deoxy-alpha-D-glucose + H2O.


name: transforming growth factor beta production

description: The appearance of any member of the transforming growth factor-beta family of cytokines due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Transforming growth factor-beta family members include TGF-B1, TGF-B2, and TGF-B3.


name: regulation of angioblast cell migration involved in selective angioblast sprouting

description: Any process that modulates the frequency, rate or extent of angioblast cell migration involved in selective angioblast sprouting.


name: response to 1-aminocyclopropane-1-carboxylic acid

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 1-aminocyclopropane-1-carboxylic acid stimulus.


Toll signaling pathway

description: The series of molecular signals initiated by an extracellular ligand binding to the receptor Toll on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.


name: positive regulation of cilium-dependent cell motility

description: Any process that activates or increases the frequency, rate or extent of cilium-dependent cell motility.


name: plant-type cell wall loosening involved in abscission

description: Any plant-type cell wall loosening that is involved in abscission.


apoptotic chromosome condensation

description: The compaction of chromatin during apoptosis.


name: negative regulation of keratinocyte migration

description: Any process that stops, prevents, or reduces the frequency, rate or extent of keratinocyte migration.


description: Catalysis of the reaction: 2-methylene-3-methylsuccinate = dimethylmaleate.


2-hydroxyglutarate synthase activity

description: Catalysis of the reaction: glyoxylate + H2O + propanoyl-CoA = 2-hydroxyglutarate + CoA + H+.


name: regulation of smooth muscle tissue development

description: Any process that modulates the frequency, rate or extent of smooth muscle tissue development.


name: positive regulation of salivary gland formation by mesenchymal-epithelial signaling

description: Any process that induces the formation of the salivary gland field by means of the secretion of a signal by a mesenchymal cell and its reception and interpretation by an epithelial cell resulting in it adopting the identity of a salivary gland bud cell.


curcumin catabolic process

description: The chemical reactions and pathways resulting in the breakdown of the polyphenol, curcumin.


name: viral release from host cell by cytolysis

description: The dissemination of mature viral particles from a host cell by the rupture of cell membranes and the loss of cytoplasm.


name: hydroxymethylglutaryl-CoA reductase (NADH) activity

description: Catalysis of the reaction: (R)-mevalonate + CoA + 2 NAD+ = 3-hydroxy-3-methylglutaryl-CoA + 2 NADH.


name: protein localization to microtubule plus-end

description: A process in which a protein is transported to, or maintained in, a location at a microtubule plus-end.


name: negative regulation of natural killer cell activation

description: Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer cell activation.


name: symbiont-mediated perturbation of host actin cytoskeleton

description: The process in which an organism effects a change that impairs the structure or function of the host actin cytoskeleton. The host is defined as the larger of the organisms involved in a symbiotic interaction.


alginate synthase activity

description: Catalysis of the reaction: GDP-D-mannuronate + alginate(n) = GDP + alginate(n+1).


name: peptide-methionine (R)-S-oxide reductase activity

description: Catalysis of the reaction: peptide-L-methionine + H2O + thioredoxin disulfide = peptide-L-methionine (R)-S-oxide + thioredoxin. Can act on oxidized methionine in peptide linkage with specificity for the R enantiomer. Thioredoxin disulfide is the oxidized form of thioredoxin.


description: The chemical reactions and pathways resulting in the formation of 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA, a derivative of coenzyme A.


UFM1 activating enzyme activity

description: Catalysis of the activation of the small ubiquitin-related modifier UFM1, through the formation of an ATP-dependent high-energy thiolester bond.


regulation of leaf morphogenesis

description: Any process that modulates the frequency, rate or extent of leaf morphogenesis.


name: negative regulation of actin filament severing

description: Any process that stops, prevents or reduces the frequency, rate or extent of actin filament severing.


name: dichotomous subdivision of terminal units involved in salivary gland branching

description: The process in which a salivary epithelial cord bifurcates at its end.


name: isoursodeoxycholate 7-beta-dehydrogenase (NAD+) activity

description: Catalysis of the reaction: 3beta,7beta-dihydroxy-5beta-cholan-24-oate + NAD+ = 3beta-hydroxy-7-oxo-5beta-cholan-24-oate + H+ + NADH.


lanosterol O-acyltransferase activity

description: Catalysis of the reaction: acyl-CoA + lanosterol = CoA + lanosterol ester.


name: symbiont-mediated suppression of host calcium or calmodulin-mediated signal transduction

description: A process in which a virus interferes with, inhibits or disrupts a calcium or calmodulin-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.


nitrous-oxide reductase activity

description: Catalysis of the reaction: H2O + 2 cytochrome c + nitrogen = 2 reduced cytochrome c + nitrous oxide.


ERBB4-EGFR signaling pathway

description: The series of molecular signals transmitted by a heterodimeric complex of the tyrosine kinase receptors EGFR (epidermal growth factor receptor/ERBB1) and ERBB4. The pathway begins with binding of a ligand to either cell surface receptor, or the dimeric receptor complex, and ends with regulation of a downstream cellular process, e.g. transcription.


name: negative regulation of antipodal cell differentiation

description: Any process that stops, prevents, or reduces the frequency, rate or extent of antipodal cell differentiation.


name: lysine N-acetyltransferase activity, acting on acetyl phosphate as donor

description: Catalysis of the reaction: acetyl phosphate + L-lysine = phosphate + N6-acetyl-L-lysine.


name: protein kinase C-activating G protein-coupled receptor signaling pathway

description: The series of molecular signals generated as a consequence of a G protein-coupled receptor binding to its physiological ligand, where the pathway proceeds with activation of protein kinase C (PKC). PKC is activated by second messengers including diacylglycerol (DAG).


propanediol channel activity

description: Enables the energy-independent facilitated diffusion of propanediol through a transmembrane aqueous pore or channel.


haloperoxidase activity

description: Catalysis of the reaction: R-CH + a halogen + H2O2 = R-C-halogen + H2O.


name: bacterial-type DNA replication termination

description: Any DNA replication termination that is involved in bacterial-type DNA replication.


name: somatic diversification of variable lymphocyte receptors of jawless fish

description: The somatic process that results in the generation of sequence diversity of the variable lymphocyte receptors (VLR) of jawless fish.


name: glycerol-3-phosphate dehydrogenase (NADP+) activity

description: NADP+ + sn-glycerol 3-phosphate = dihydroxyacetone phosphate + H+ + NADPH.


name: negative regulation of mitotic spindle elongation

description: Any process that stops, prevents or reduces the frequency, rate or extent of mitotic spindle elongation.


name: positive regulation of gonadotropin secretion

description: Any process that activates or increases the frequency, rate or extent of the regulated release of a gonadotropin.


name: undecaprenyl-phosphate glucose phosphotransferase activity

description: Catalysis of the reaction: UDP-glucose + ditrans,octacis-undecaprenyl phosphate = UMP + alpha-D-glucopyranosyl-diphospho-ditrans,octacis-undecaprenol.


tolerance induction to tumor cell

description: A process of tolerance induction which leads to immunological tolerance of a tumor.


cortisol sulfotransferase activity

description: Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + cortisol = adenosine 3',5'-diphosphate + cortisol 21-sulfate + H+.


name: B cell proliferation involved in immune response

description: The expansion of a B cell population by cell division following B cell activation during an immune response.


AAG codon-amino acid adaptor activity

description: A triplet codon-amino acid adaptor activity that recognizes an AAG codon.


isocitrate lyase activity

description: Catalysis of the reaction: isocitrate = glyoxylate + succinate.


name: perturbation of blood coagulation in another organism

description: The process in which an organism effects a change that affects blood coagulation in another organism. Blood coagulation is the sequential process in which the multiple coagulation factors of the blood interact, ultimately resulting in the formation of an insoluble fibrin clot.


name: calcitonin gene-related peptide receptor signaling pathway

description: The series of molecular signals initiated by an extracellular calcitonin gene-related peptide (CGRP) combining with a calcitonin gene-related peptide receptor on the surface of the target cell. Calcitonin gene-related peptide receptors may form dimers, trimers or tetramers.


name: negative regulation of cardiac muscle tissue growth

description: Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle growth.


name: satellite cell activation involved in skeletal muscle regeneration

description: The process that initiates skeletal muscle satellite cell division by causing it to move from quiescence to the G1 stage of the cell cycle. The cell swells and there are a number of other small changes. The cells then start to divide. Following cell division the cells will differentiate. In adult muscle, satellite cells become activated to divide and differentiate in response to muscle damage.


alpha-glucan biosynthetic process

description: The chemical reactions and pathways resulting in the formation of alpha-glucans, compounds composed of glucose residues linked by alpha-D-glucosidic bonds.


name: pigment biosynthetic process involved in pigment granule maturation

description: The chemical reactions and pathways resulting in the formation of a pigment, contributing to the process in which a membrane-bounded organelle develops into a pigment granule. Maturation is a developmental process, independent of morphogenetic (shape) change, that is required for a cell or structure to attain its fully functional state.


mating plug formation

description: The deposition of a plug of sperm or other gelatinous material into the opening of the vulva by a male at the termination of copulation. Probably acts to prevent subsequent matings by other males.


name: positive regulation of DNA recombination at telomere

description: Any process that activates or increases the frequency, rate or extent of DNA recombination within the telomere.


vascular process in circulatory system

description: A circulatory process that occurs at the level of the vasculature.


response to 3-methylcholanthrene

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 3-methylcholanthrene stimulus.


JUN kinase kinase activity

description: Catalysis of the phosphorylation of tyrosine and threonine residues in a c-Jun NH2-terminal kinase (JNK), a member of a subgroup of mitogen-activated protein kinases (MAPKs), which signal in response to cytokines and exposure to environmental stress. JUN kinase kinase (JNKK) is a dual-specificity protein kinase kinase and requires activation by a serine/threonine kinase JUN kinase kinase kinase.


embryonic hemocyte differentiation

description: The process in which a relatively unspecialized cell derived from the embryonic head mesoderm acquires the specialized features of a mature hemocyte. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen.


pyridoxine 5-dehydrogenase activity

description: Catalysis of the reaction: pyridoxine + acceptor = isopyridoxal + reduced acceptor.


description: Catalysis of the reaction: chenodeoxycholoyltaurine + H2O = chenodeoxycholate + taurine.


name: gibberellin A12, 2-oxoglutarate:oxygen oxidoreductase activity (gibberellin A15-forming)

description: Catalysis of the reaction: gibberellin A12 + O2 + 2-oxoglutarate = gibberellin A15 + carbon dioxide + succinate.


name: negative regulation of regulatory T cell differentiation

description: Any process that stops, prevents, or reduces the rate of differentiation of regulatory T cells.


name: sodium:dicarboxylate symporter activity

description: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: dicarboxylate(out) + Na+(out) = dicarboxylate(in) + Na+(in).


atrazine metabolic process

description: The chemical reactions and pathways involving atrazine, a triazine ring-containing compound, widely used as a herbicide.


name: positive regulation of Wnt signaling pathway by establishment of Wnt protein localization to extracellular region

description: Any process that activates or increases the frequency, rate or extent of the Wnt signaling pathway by the directed movement of a Wnt protein within the extracellular region.


acetoin racemase activity

description: Catalysis of the reaction: (S)-acetoin = (R)-acetoin.


name: regulation of glycine import across plasma membrane

description: Any process that modulates the frequency, rate or extent of glycine import into a cell.


description: Catalysis of the transfer of a myristoyl (systematic name, tetradecanoyl) group to a sulfur atom on a cysteine residue of a protein molecule in the reaction: tetradecanoyl-CoA + L-cysteinyl-[protein] = CoA + S-tetradecanoyl-L-cysteinyl-[protein].


purine nucleosidase activity

description: Catalysis of the reaction: a N-D-ribosylpurine + H2O = a purine + D-ribose.


name: 16:0 monogalactosyldiacylglycerol desaturase activity

description: Catalysis of the introduction of an omega-3 double bond into an unsaturated 16-carbon fatty acid in a monogalactosyldiacylglycerol molecule.


name: noradrenergic neuron differentiation involved in brainstem development

description: The process in which a relatively unspecialized cell acquires specialized features of an noradrenergic neuron that is part of the brainstem.


name: negative regulation of striated muscle tissue development

description: Any process that stops, prevents, or reduces the frequency, rate or extent of striated muscle development.


1-penten-3-one reductase activity

description: Catalysis of the reaction: 1-penten-3-one + NADPH + H+ = 1-pentan-3-one + NADP.


epithelial-mesenchymal cell signaling

description: Any process that results in the transfer of information from an epithelial cell to a mesenchymal cell where it is interpreted.


description: Catalysis of the reaction: 16-alpha-hydroxyprogesterone = H2O + 16-dehydroprogesterone.


name: nickel incorporation into nickel-iron-sulfur cluster via pentakis-L-cysteinyl L-histidino nickel tetrairon pentasulfide

description: The incorporation of nickel into a nickel-iron-sulfur cluster via pentakis-L-cysteinyl L-histidino nickel tetrairon pentasulfide, found in carbon monoxide dehydrogenase.


name: positive regulation of B cell differentiation

description: Any process that activates or increases the frequency, rate or extent of B cell differentiation.


CTP catabolic process

description: The chemical reactions and pathways resulting in the breakdown of CTP, cytidine 5'-triphosphate.


dense core granule localization

description: Any process in which a dense core granule is transported to, and/or maintained in, a specific location within the cell.


tyrosine 3-monooxygenase activity

description: Catalysis of the reaction: L-tyrosine + tetrahydrobiopterin + O2 = 3,4-dihydroxy-L-phenylalanine + 4-alpha-hydroxytetrahydrobiopterin + H2O.


description: Catalysis of the reaction: 5,10-methylenetetrahydrofolate + D-alanine + H2O = (6S)-5,6,7,8-tetrahydrofolate + 2-methylserine.


name: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase activity (ferredoxin)

description: Catalysis of the reaction: (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate + H2O + 2 oxidized ferredoxin = 2-C-methyl-D-erythritol 2,4-cyclodiphosphate + 2 reduced ferredoxin.


name: larval salivary gland boundary specification

description: Determination in a larval organism of where the salivary gland forms, the total number of salivary gland cells and how many cells are allocated to each of the specialised cell types within the salivary gland.


name: cell adhesion involved in biofilm formation

description: The attachment of a cell to a solid substrate, via cell adhesion molecules, contributing to the formation of a biofilm.


antisense RNA transcription

description: The synthesis of antisense RNA, an RNA molecule complementary in sequence to another RNA or DNA molecule, which, by binding the latter, acts to inhibit its function and/or completion of synthesis, on a template of DNA.


cellular response to cycloheximide

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cycloheximide stimulus. Cycloheximide (actidione) is an antibiotic produced by some Streptomyces species which interferes with protein synthesis in eukaryotes.


description: The chemical reactions and pathways resulting in the formation of 10-formyltetrahydrofolate, the formylated derivative of tetrahydrofolate.


propioin synthase activity

description: Catalysis of the reaction: 4-hydroxyhexan-3-one = 2 propanal.


name: asymmetric protein localization to old mitotic spindle pole body

description: Any process in which a protein is transported to, or maintained to the old mitotic spindle pole body resulting in its being distributed asymmetrically.


thymidine biosynthetic process

description: The chemical reactions and pathways resulting in the formation of thymidine, deoxyribosylthymine thymine 2-deoxyriboside, a deoxynucleoside very widely distributed but occurring almost entirely as phosphoric esters in deoxynucleotides and deoxyribonucleic acid, DNA.


geranylgeraniol kinase activity

description: Catalysis of the reaction: geranylgeraniol + nucleoside triphosphate = all-trans-geranyl-geranyl monophosphate + nucleoside diphosphate.


name: regulation of smooth muscle cell chemotaxis

description: Any process that modulates the frequency, rate, or extent of smooth muscle cell chemotaxis.


name: cysteine biosynthetic process from serine

description: The chemical reactions and pathways resulting in the formation of cysteine from other compounds, including serine.


name: 5-amino-1-ribofuranosylimidazole-4-carboxamide transmembrane transporter activity

description: Enables the transfer of 5-amino-1-ribofuranosylimidazole-4-carboxamide from one side of a membrane to the other.


description: Catalysis of the reaction: poly(ribitol phosphate) + UDP-N-acetyl-D-glucosamine = N-acetyl-D-glucosaminyl-poly(ribitol phosphate) + UDP.


name: detection of mechanical stimulus involved in sensory perception

description: The series of events in which a mechanical stimulus is received and converted into a molecular signal as part of sensory perception.


name: symbiont-mediated perturbation of host inflammatory response

description: A process in which a symbiont alters or subverts the normal execution of the  inflammatory response of the host organism; the inflammatory response is the immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The host is defined as the larger of the organisms involved in a symbiotic interaction.


name: dopamine neurotransmitter receptor activity, coupled via Gs

description: Combining with the neurotransmitter dopamine and activating adenylate cyclase via coupling to Gs to initiate a change in cell activity.


name: low-density lipoprotein particle remodeling

description: The acquisition, loss or modification of a protein or lipid within a low-density lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase, with the subsequent loss of free fatty acid, and the transfer of cholesterol esters from LDL to a triglyceride-rich lipoprotein particle by cholesteryl ester transfer protein (CETP), with the simultaneous transfer of triglyceride to LDL.


description: Catalysis of the reaction: N-acetyl-beta-D-glucosaminyl-1,3-N-acetyl-D-galactosaminyl-R + UDP-N-acetyl-D-glucosamine = N-acetyl-beta-D-glucosaminyl-1,6-(N-acetyl-beta-D-glucosaminyl-1,3)-N-acetyl-D-galactosaminyl-R + UDP.


GA5 3beta-hydroxylase activity

description: Catalysis of the reaction: gibberellin A5 + O2 + 2-oxoglutarate = gibberellin A3 + succinate + carbon dioxide.


name: Actinobacterium-type cell wall biogenesis

description: A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cell wall of the type found in Actinobacteria. The cell wall is the rigid or semi-rigid envelope lying outside the cell membrane. Actinobacterial cell walls contain characteristic mycolic acids, of which some are covalently linked to the cell wall peptidoglycan and others accumulate at the cell surface.


determination of adult lifespan

description: The pathways that regulate the duration of the adult phase of the life-cycle of an animal.


name: negative regulation of cytotoxic T cell differentiation

description: Any process that stops, prevents, or reduces the frequency, rate or extent of cytotoxic T cell differentiation.


name: imidazole-containing compound catabolic process

description: The chemical reactions and pathways resulting in the breakdown of imidazoles, five-membered organic heterocycle containing two nitrogen atoms at positions 1 and 3, or any of its derivatives; compounds containing an imidazole skeleton.


synaptic target inhibition

description: The process in which a neuronal cell in a multicellular organism recognizes chemorepellent signals that inhibit its growth toward the source.


anterior commissure morphogenesis

description: Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in one half of the cerebral cortex towards target cells in the contralateral half. This axonal process is a member of those that make up the anterior commissure, a small midline fiber tract that lies at the anterior end of the corpus callosum.


regulation of cell cycle checkpoint

description: Any process that modulates the frequency, rate or extent of cell cycle checkpoint.


name: regulation of plasmatocyte differentiation

description: Any process that modulates the frequency, rate or extent of plasmatocyte differentiation.


name: scutellarein 7-methyl ether 6-O-methyltransferase activity

description: Catalysis of the reaction: scutellarein 7-methyl ether + S-adenosyl-L-methionine = cirsimaritin + S-adenosyl-L-homocysteine + H+.


L-histidine metabolic process

description: The chemical reactions and pathways involving L-histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid.


limb joint morphogenesis

description: The process in which the anatomical structures of a limb joint are generated and organized. A limb joint is a flexible region that separates the rigid sections of a limb to allow movement in a controlled manner.


aldose 1-dehydrogenase activity

description: Catalysis of the reaction: D-aldose + NAD+ = D-aldonolactone + NADH.


methylglyoxal synthase activity

description: Catalysis of the reaction: glycerone phosphate = methylglyoxal + phosphate.


peptidyl-tyrosine uridylylation

description: The uridylylation of peptidyl-tyrosine to form peptidyl-O4'-(phospho-5'-uridine)-L-tyrosine, found in glutamine synthetase.


protein deglycase activity

description: Catalysis of the removal of a sugar or dicarbonyl from a glycated L-arginine, L-lysine or L-cysteine residue within proteins that have been attacked and modified by glyoxal or 2-oxopropanal.


name: fungal-type cell wall (1->3)-alpha-glucan metabolic process

description: The chemical reactions and pathways involving (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in the walls of ascospores.


name: negative regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation

description: Any process that stops, prevents or reduces the frequency, rate or extent of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation.


vestibulocochlear nerve development

description: The process whose specific outcome is the progression of the vestibulocochlear nerve over time, from its formation to the mature structure. This sensory nerve innervates the membranous labyrinth of the inner ear. The vestibular branch innervates the vestibular apparatus that senses head position changes relative to gravity. The auditory branch innervates the cochlear duct, which is connected to the three bony ossicles which transduce sound waves into fluid movement in the cochlea.


photosynthesis, light harvesting

description: Absorption and transfer of the energy absorbed from light photons between photosystem reaction centers.


name: establishment of melanosome localization

description: The directed movement of a melanosome to a specific location.


name: coenzyme F420-dependent 2,4,6-trinitrophenol reductase activity

description: Catalysis of the reaction: 2,4,6-trinitrophenol + H- = 2,4,6-trinitrophenol hydride Meisenheimer complex. Coenzyme F420 supplies the hydride (H-) in the reaction.


response to abscisic acid

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abscisic acid stimulus.


guanylate kinase activity

description: Catalysis of the reaction: ATP + GMP = ADP + GDP.


name: T cell mediated immune response to tumor cell

description: An immune response mediated by a T cell triggered in response to the presence of a tumor cell.


cyanuric acid amidohydrolase activity

description: Catalysis of the reaction: cyanurate + H2O = 1-carboxybiuret + H+.


chloroplast elongation

description: Expansion of the chloroplast that usually precedes division.


deoxyuridine 2'-dioxygenase activity

description: Catalysis of the reaction: 2'-deoxyuridine + 2-oxoglutarate + O2 = CO2 + succinate + uridine.


cytotoxic T cell pyroptotic cell death

description: A pyroptotic cell death process that occurs in a cytotoxic T cell.


neuron fate determination

description: The process in which a cell becomes capable of differentiating autonomously into a neuron regardless of its environment; upon determination, the cell fate cannot be reversed.


name: positive regulation of monoatomic anion transport

description: Any process that activates or increases the frequency, rate or extent of anion transport.


name: regulation of mammary gland epithelial cell proliferation

description: Any process that modulates the frequency, rate or extent of mammary gland epithelial cell proliferation.


name: regulation of natural killer cell differentiation

description: Any process that modulates the frequency, rate or extent of natural killer cell differentiation.


central nervous system myelin formation

description: The process in which the wraps of cell membrane that constitute myelin are laid down around an axon by an oligodendrocyte in the central nervous system.


name: regulation of amino acid transmembrane transport

description: Any process that modulates the frequency, rate or extent of amino acid transmembrane transport.


name: convergent extension involved in organogenesis

description: The morphogenetic process in which an epithelium narrows along one axis and lengthens in a perpendicular axis contribution to the shaping of an organ.


name: regulation of systemic arterial blood pressure by aortic body chemoreceptor signaling

description: The process that modulates blood pressure by the action of chemoreceptors found in the aortic bodies and their resultant modulation of the vasomotor center. Chemoreceptors respond to oxygen, carbon dioxide and hydrogen ions.


sensory perception of wind

description: The series of events required for an organism to receive sensory mechanical stimulus resulting from air flow, convert it to a molecular signal, and recognize and characterize the signal.


syncytial blastoderm mitotic cell cycle

description: Mitotic division cycles 10 to 13 of the insect embryo. This is the second phase of the syncytial period where nuclei divide in a common cytoplasm without cytokinesis. The majority of migrating nuclei reach the embryo surface during cycle 10, after which they divide less synchronously than before, and the syncytial blastoderm cycles lengthen progressively.


name: negative regulation of establishment of competence for transformation

description: Any process that stops, prevents, or reduces the frequency, rate or extent of establishment of competence for transformation.


1,2-dichloroethane metabolic process

description: The chemical reactions and pathways involving 1,2-dichloroethane, a major commodity chemical used, for example, in the manufacture of vinyl chloride.


name: negative regulation of encysted zoospore germination

description: Any process that stops, prevents, or reduces the frequency, rate or extent of encysted zoospore germination.


name: negative regulation of low-density lipoprotein particle clearance

description: Any process that decreases the rate, frequency or extent of low-density lipoprotein particle clearance. Low-density lipoprotein particle clearance is the process in which a low-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.


description: Catalysis of the reaction: 4-coumaryl-CoA + pelargonidin 3-O-beta-D-glucoside = pelargonidin 3-O-beta-D-p-coumaroylglucoside + coenzyme A.


farnesol dehydrogenase activity

description: Catalysis of the reaction: 2-trans,6-trans-farnesol + NADP+ = 2-trans,6-trans-farnesal + H+ + NADPH.


name: negative regulation of tolerance induction

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of tolerance induction.


name: negative regulation of stem cell differentiation

description: Any process that stops, prevents or reduces the frequency, rate or extent of stem cell differentiation.


3-oxolaurate decarboxylase activity

description: Catalysis of the reaction: 3-oxolaurate + H+ = 2-undecanone + CO2.


2-hexadecenal reductase activity

description: Catalysis of the reaction: NADP+ + palmitaldehyde = trans-hexadec-2-enal + H+ + NADPH.


name: membrane reorganization involved in phagocytosis, engulfment

description: The assembly and arrangement of the plasma membrane that is involved in the internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis.


name: negative regulation of endothelial cell development

description: Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell development.


name: inward migration of deep nuclear neurons

description: The directed movement of a deep nuclear neuron from the rostrodorsal region of the cerebellar plate to their final more ventral position.


name: positive regulation of norepinephrine uptake

description: Any process that activates or increases the frequency, rate or extent of the directed movement of norepinephrine into a cell.


adenine metabolic process

description: The chemical reactions and pathways involving adenine, 6-aminopurine, one of the five main bases found in nucleic acids and a component of numerous important derivatives of its corresponding ribonucleoside, adenosine.


name: symbiont entry into host cell via permeabilization of endosomal membrane

description: The entry of a symbiont into a host cell, following endocytosis, via permeabilization of the endosomal membrane by membrane penetration protein(s) of the symbiont. This process mediates the entry of some non-enveloped virus into eukaryotic cells. In some cases, viral membrane-penetration protein requires to be activated to display its membrane penetrating activity. Activation can be due to receptor binding or the acidic pH of the endosomal lumen.


citronellyl-CoA ligase activity

description: Catalysis of the reaction: citronellate + CoASH + ATP = citronellyl-CoA + AMP + PPi.


name: regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis

description: Any process that modulates the frequency, rate or extent of cardiac neural crest cell migration involved in outflow tract morphogenesis.


protein localization to early endosome

description: A process in which a protein is transported to, or maintained in, a location within an early endosome.


name: indoleacetic acid conjugate metabolic process

description: The chemical reactions and pathways involving any indole-3-acetic acid conjugate, a form of indoleacetic acid covalently bound to another molecule.


name: positive regulation of ARF protein signal transduction

description: Any process that activates or increases the frequency, rate or extent of ARF protein signal transduction.


name: peptidyl-S-palmitoleyl-L-cysteine biosynthetic process from peptidyl-cysteine

description: The modification of peptidyl-cysteine to form peptidyl-S-palmitoleyl-L-cysteine specifically.


name: guanine transmembrane transporter activity

description: Enables the transfer of guanine, 2-amino-6-hydroxypurine, from one side of a membrane to the other.


cellular response to nitrogen levels

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of inorganic nitrogen.


cAMP deaminase activity

description: Catalysis of the reaction: cyclic adenosine monophosphate + H2O = cyclic inosine monophosphate + NH3.


name: isopropylmalate transmembrane transporter activity

description: Enables the transfer of isopropylmalate from one side of a membrane to the other.


C-22 sterol desaturase activity

description: Catalysis of the formation of the C-22(23) double bond in the sterol side chain. An example reaction: 5,7,24(28)-ergostatrienol + O2 + NADPH = 5,7,22,24(28)-ergostatetraenol + 2 H2O + NADP+.


heparan sulfate binding

description: Binding to heparan sulfate.


name: negative regulation of fusion cell fate specification

description: Any process that restricts, stops or prevents a cell from adopting a fusion cell fate. Once the terminal and fusion fates have been correctly induced, inhibitory feedback loops prevent the remaining branch cells from assuming similar fates.


negative regulation of cell killing

description: Any process that stops, prevents, or reduces the frequency, rate or extent of cell killing.


cellular hyperosmotic salinity response

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, an increase in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.


ketone catabolic process

description: The chemical reactions and pathways resulting in the breakdown of ketones, a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups.


uterine smooth muscle contraction

description: A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the uterus. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The uterus is a muscular organ of the female mammal for containing and usually for nourishing the young during development prior to birth.


name: positive regulation of toll-like receptor 15 signaling pathway

description: Any process that activates or increases the frequency, rate or extent of toll-like receptor 15 signaling pathway.


name: regulation of cellular response to phosphate starvation

description: Any process that modulates the frequency, rate or extent of cellular response to phosphate starvation.


name: adenine nucleotide transmembrane transporter activity

description: Enables the transfer of adenine nucleotides (AMP, ADP, and ATP) from one side of a membrane to the other.


regulation of acetylcholine uptake

description: Any process that modulates the frequency, rate or extent of the directed movement of the neurotransmitter acetylcholine into a cell.


name: neuron development involved in amphid sensory organ development

description: The process whose specific outcome is the progression of a neuron over time, that contributes to the development of the amphid sensory organ.


alkali metal ion binding

description: Binding to an alkali metal ion; alkali metals are those elements in group Ia of the periodic table, with the exception of hydrogen.


alternative oxidase activity

description: Catalysis of the oxidation of ubiquinol by diverting electrons from the standard electron transfer chain, transferring them from ubiquinol to oxygen and generating water as the product.


histone H3 methyltransferase activity

description: Catalysis of the reaction: S-adenosyl-L-methionine + a histone H3 = S-adenosyl-L-homocysteine + a methylated histone H3. Histone methylation generally occurs on either an arginine or a lysine residue.


name: positive regulation of response to calcium ion

description: Any process that activates or increases the frequency, rate or extent of response to calcium ion.


name: regulation of chlorophyll biosynthetic process

description: Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of chlorophyll, any compound of magnesium complexed in a porphyrin (tetrapyrrole) ring and which functions as a photosynthetic pigment, from less complex precursors.


name: xanthine transmembrane transporter activity

description: Enables the transfer of xanthine from one side of a membrane to the other. Xanthine (2,6-dihydroxypurine) is a purine formed in the metabolic breakdown of guanine, but is not present in nucleic acids.


name: proteolysis within endoplasmic reticulum associated with antigen processing and presentation

description: The hydrolysis of a peptide bond or bonds within a protein by ER resident proteases contributing to antigen processing and presentation.


name: negative regulation of inward rectifier potassium channel activity

description: Any process that stops, prevents or reduces the frequency, rate or extent of inward rectifier potassium channel activity.


description: Catalysis of the reaction: UDP-alpha-D-glucose(2-) + trans-zeatin = H+ + 9-(alpha-D-glucosyl)-trans-zeatin + UDP(3-).


name: positive regulation of wound healing, spreading of epidermal cells

description: Any process that activates or increases the frequency, rate or extent of wound healing, spreading of epidermal cells.


name: dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity

description: Catalysis of the addition of the first glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation; the transfer of glucose from dolichyl phosphate glucose (Dol-P-Glc) on to the lipid-linked oligosaccharide Man(9)GlcNAc(2)-PP-Dol.


nuclear pore complex assembly

description: The aggregation, arrangement and bonding together of a set of components to form a nuclear pore complex.


description: Catalysis of the reaction: UDP-N-acetyl-D-galactosamine + alpha-D-galactosyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosylceramide = UDP + beta-N-acetyl-D-galactosaminyl-(1->3)-alpha-D-galactosyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosylceramide.


name: protein localization to cytoplasmic microtubule plus-end

description: A process in which a protein is transported to, or maintained in, a location at a cytoplasmic microtubule plus-end.


name: positive regulation of necroptotic process

description: Any process that increases the rate, frequency or extent of a necroptotic process, a necrotic cell death process that results from the activation of endogenous cellular processes, such as signaling involving death domain receptors or Toll-like receptors.


name: negative regulation of myeloid cell apoptotic process

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of a myeloid cell apoptotic process.


negative regulation of eye pigmentation

description: Any process that stops, prevents, or reduces the frequency, rate or extent of establishment of a pattern of pigment in the eye of an organism.


peptidyl-tyrosine sulfation

description: The sulfation of peptidyl-tyrosine residues to form peptidyl-O4'-sulfo-L-tyrosine.


hemidesmosome assembly

description: Assembly of hemidesmosomes, integrin-containing protein complexes that bind to laminin in the basal lamina. Hemidesmosomes form the contact between the basal surface of epithelial cells and the underlying basal lamina.


telencephalon development

description: The process whose specific outcome is the progression of the telencephalon over time, from its formation to the mature structure. The telencephalon is the paired anteriolateral division of the prosencephalon plus the lamina terminalis from which the olfactory lobes, cerebral cortex, and subcortical nuclei are derived.


description: Catalysis of the reaction: peptidyl L-asparagine + 2-oxoglutarate + O2 = peptidyl 3-hydroxy-L-asparagine + succinate + CO2.


2',3'-cyclic GMP-AMP synthase activity

description: Catalysis of the reaction: ATP + GTP = 2 diphosphate + cyclic G-P(2'-5')A-P(3'-5') (cyclic 2',3' GAMP).


name: negative regulation of telomerase RNA localization to Cajal body

description: Any process that stops, prevents or reduces the frequency, rate or extent of telomerase RNA localization to Cajal body.


name: peptide antigen assembly with MHC protein complex

description: The binding of a peptide to the antigen binding groove of an MHC protein complex.


name: positive regulation of trophoblast cell migration

description: Any process that activates or increases the frequency, rate or extent of trophoblast cell migration.


name: envenomation resulting in negative regulation of acid-sensing ion channel activity in another organism

description: A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant negative regulation in the activity of an acid-sensing ion channel (ASIC) in the bitten organism.


metanephric nephron morphogenesis

description: The process in which the anatomical structures of the metanephric nephron are generated and organized. A metanephric nephron is the functional unit of the metanephros.


vistamycin catabolic process

description: The chemical reactions and pathways resulting in the breakdown of vistamycin.


cyclopentanol catabolic process

description: The chemical reactions and pathways resulting in the breakdown of cyclopentanol.


name: COPI coating of Golgi vesicle, cis-Golgi to rough ER

description: The addition of COPI proteins and adaptor proteins to Golgi membranes during the formation of cis-Golgi to rough ER transport vesicles, forming a vesicle coat.


name: antigen processing and presentation of peptide antigen

description: The process in which an antigen-presenting cell expresses peptide antigen in association with an MHC protein complex on its cell surface, including proteolysis and transport steps for the peptide antigen both prior to and following assembly with the MHC protein complex. The peptide antigen is typically, but not always, processed from an endogenous or exogenous protein.


quinone biosynthetic process

description: The chemical reactions and pathways resulting in the formation of quinone.


epsilon-caprolactam lactamase activity

description: Catalysis of the reaction: epsilon-caprolactam + H2O = H+ + 6-aminohexanoate.


cellular response to sterol

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sterol stimulus.


DNA transmembrane transporter activity

description: Enables the transfer of DNA, deoxyribonucleic acid, from one side of a membrane to the other.


name: cell chemotaxis to fibroblast growth factor

description: The directed movement of a motile cell in response to the presence of fibroblast growth factor (FGF).


name: adenylate cyclase-inhibiting serotonin receptor signaling pathway

description: An adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway initiated by serotonin binding to its receptor, and ending with the regulation of a downstream cellular process.


nicotinate catabolic process

description: The chemical reactions and pathways resulting in the breakdown of nicotinate.


endoglycosylceramidase activity

description: Catalysis of the reaction: H2O + oligoglycosylglucosylceramide = ceramide + oligoglycosylglucose.


name: regulation of the force of heart contraction

description: Any process that modulates the extent of heart contraction, changing the force with which blood is propelled.


description: Catalysis of the reaction: cyclooctat-9-en-7-ol + O2 + NADPH + H+ = cyclooctat-9-en-5,7-diol + H2O + NADP.


name: di-homo-gamma-linolenate delta5 desaturase activity

description: Catalysis of the reaction: all-cis-icosa-8,11,14-trienoate + O2 + a reduced electron acceptor = arachidonate + 2 H2O + an oxidized electron acceptor.


name: indolelactate dehydrogenase (NAD+) activity

description: Catalysis of the reaction: 3-(indol-3-yl)lactate + NAD+ = 3-(indol-3-yl)pyruvate + H+ + NADH.


RNA-dependent RNA polymerase activity

description: Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1); uses an RNA template, i.e. the catalysis of RNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.


action potential initiation

description: The initiating cycle of an action potential. In vertebrate neurons this typically occurs at an axon hillock. Not all initiated axon potentials propagate.


maleylacetate reductase activity

description: Catalysis of the reaction: 3-oxoadipate + NAD(P)+ = 2-maleylacetate + NAD(P)H + H+.


ergothioneine biosynthetic process

description: The chemical reactions and pathways resulting in the formation of ergothioneine, a naturally occurring metabolite of histidine with antioxidant properties.


peptide N-succinyltransferase activity

description: Catalysis of the acetylation of an amino acid residue of a peptide or protein, according to the reaction: succinyl-CoA + peptide = CoA + N-succinylpeptide.


name: spinal cord commissural neuron specification

description: The process in which a cell becomes capable of differentiating autonomously into a commissural neuron in an environment that is neutral with respect to the developmental pathway.


name: carcinine transmembrane transporter activity

description: Enables the transfer of carcinine from one side of a membrane to the other.


regulation of phenotypic switching

description: Any process that modulates the frequency, rate or extent of phenotypic switching.


endocrocin catabolic process

description: The chemical reactions and pathways resulting in the breakdown of endocrocin.


purine ribonucleoside salvage

description: Any process which produces a purine nucleoside from derivatives of it, without de novo synthesis.


pheophorbide a oxygenase activity

description: Catalysis of the reaction: pheophorbide a + reduced ferredoxin + 2 O2 = red chlorophyll catabolite + oxidized ferredoxin + H2O.


NAD transmembrane transporter activity

description: Enables the transfer of NAD from one side of a membrane to the other.


name: precorrin-6A synthase (deacetylating) activity

description: Catalysis of the reaction: S-adenosyl-L-methionine + H2O + precorrin-5 = S-adenosyl-L-homocysteine + acetate + 2 H+ + precorrin-6X.


name: acute inflammatory response to non-antigenic stimulus

description: An acute inflammatory response to non-antigenic stimuli such as heat or physical trauma.


name: regulation of cell wall (1->3)-alpha-glucan metabolic process

description: Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in the walls of cells.


name: pyrimidine-containing compound biosynthetic process

description: The chemical reactions and pathways resulting in the formation of a pyrimidine-containing compound, i.e. any compound that contains pyrimidine or a formal derivative thereof.


name: positive regulation of prolactin signaling pathway

description: Any process that activates or increases the frequency, rate or extent of prolactin signaling pathway.


name: symbiont-mediated perturbation of host ubiquitin-like protein modification

description: A process by which a symbiont alters ubiquitin-like protein modification of target proteins of either host or symbiont proteins. This includes ubiquitination, SUMOylation, NEDDylation, and ISG15ylation. The ubiquitination status of a protein  affects whether it is targeted to the proteasome for degradation. The host is defined as the larger of the organisms involved in a symbiotic interaction.


dehydropipecolic acid reductase

description: Catalysis of the reaction: dehydropipecolic acid + NAD(P)H + H+ = L-pipecolic acid + NAD(P)+.


intracellular ammonium homeostasis

description: A homeostatic process involved in the maintenance of a steady state level of ammonium within a cell.


name: gephyrin clustering involved in postsynaptic density assembly

description: The clustering process in which gephyrin molecules are localized to distinct domains in the postsynaptic density as part of postsynaptic density assembly. Gephyrin is a component of the postsynaptic protein network of inhibitory synapses.


abscisic acid homeostasis

description: Any process involved in the maintenance of an internal steady state of abscisic acid within an organism or cell.


name: mesenchymal stem cell differentiation involved in metanephric nephron morphogenesis

description: The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal stem cell that contributes to the shaping of a nephronin the metanephros. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells.


description: Catalysis of the reaction: N-acetyl-beta-alanine + H2O = beta-alanine + acetate.


tissue kallikrein-kinin cascade

description: A series of reactions that takes place outside the cell initiated by the action of tissue (glandular) kallikreins on low molecular weight kininogen in response to tissue damage. Tissue kallikreins are present in glandular tissues and their fluids, such as the salivary glands, sweat glands, pancreas, and kidney. The ultimate products of the tissue kallikrein-kinin cascade include kallidin and bradykinin, agents known to induce smooth muscle contraction, vasoconstriction, and increased vascular permeability.


opioid growth factor receptor activity

description: Combining with the opioid growth factor (OGF, met-enkephalin) and transmitting the signal across the nuclear membrane. Met-enkephalin is an endogenous opioid peptide that binds to opioid and opioid growth factor receptors, regulating tissue growth in a variety of cellular processes.


regulation of receptor recycling

description: Any process that modulates the frequency, rate, or extent of receptor recycling.


description: Catalysis of the reaction: indole-3-pyruvate + S-adenosyl-L-methionine = (R)-3-(indol-3-yl)-2-oxobutanoate + H+ + S-adenosyl-L-homocysteine.


nicotianamine aminotransferase activity

description: Catalysis of the reaction: 2-oxoglutarate + nicotianamine = 3''-deamino-3''-oxonicotianamine + L-glutamate.