vulval cell fate determination

description: The process in which a cell becomes capable of differentiating autonomously into a nematode vulval cell regardless of its environment; upon determination, the cell fate cannot be reversed. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed adult vulva, which is the egg-laying organ of female and hermaphrodite nematodes.


name: positive regulation of response to DNA integrity checkpoint signaling

category: biolink:BiologicalProcess biolink:Occurrent biolink:OntologyClass biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: Any process that activates or increases the frequency, rate or extent of response to DNA integrity checkpoint signaling.


name: negative regulation of erythrophore differentiation

description: Any process that stops, prevents, or reduces the frequency, rate or extent of erythrophore differentiation.


name: negative regulation of erythrocyte apoptotic process

description: Any process that stops, prevents or reduces the frequency, rate or extent of erythrocyte apoptotic process.


GPCR bitter taste receptor activity

category: biolink:MolecularActivity biolink:Occurrent biolink:OntologyClass biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: A G protein-coupled receptor activity that is responsible for the sense of bitter taste.


description: Catalysis of the reaction: 3 H+ + 15-cis-4,4'-diapophytoene + 4 FAD = 4,4'-diapolycopene + 3 FADH2. This reaction consists of three successive dehydrogenations that lead to the introduction of three double bonds into 4,4'-diapophytoene (dehydrosqualene), with 4,4'-diapophytofluene and 4,4'-diapo-zeta-carotene as intermediates, and 4,4'-diaponeurosporene (the major deep-yellow pigment in staphylococci strains) as the end product.


stomatal closure

description: The process of closing of stomata, pores in the epidermis of leaves and stems bordered by two guard cells and serving in gas exchange.


regulation of timing of exogen

description: Any process that modulates the frequency, rate or extent of timing of exogen, the shedding phase of the hair cycle.


name: urokinase plasminogen activator receptor activity

description: Combining with the urokinase plasminogen activator to initiate a change in cell activity.


alpha-agarase activity

description: Catalysis of the endohydrolysis of 1,3-alpha-L-galactosidic linkages in agarose, yielding agarotetraose as the major product.


name: glucosamine-containing compound biosynthetic process

description: The chemical reactions and pathways resulting in the formation of glucosamine-containing compounds (glucosamines).


cap-dependent translational initiation

description: The process where the cap structure, composed of a 7- methylguanosine (m7G) group and associated cap-binding proteins, located at the 5' end of an mRNA molecule, which serves as a molecular tag that marks the spot where the 40S ribosomal subunit, is recruited and will then scan in a 5' to 3' direction until an AUG codon is encountered in an appropriate sequence context to initiate mRNA translation.


name: proline:proton symporter activity

description: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: proline(out) + H+(out) = proline(in) + H+(in).


name: uridine:proton symporter activity

description: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: uridine(out) + H+(out) = uridine(in) + H+(in).


name: glucosinolate biosynthetic process from homomethionine

description: The chemical reactions and pathways resulting in the formation of glucosinolates from other compounds including homomethionine.


name: regulation of chronic inflammatory response

description: Any process that modulates the frequency, rate, or extent of a chronic inflammatory response.


name: cotranscriptional mitochondrial rRNA nucleotide insertion

description: The insertion of one or two non-coded nucleotides during the transcription of a mitochondrial rRNA. Such additions are known to occur in myxomycetes such as Physarum, Didymium, and Stemonitis.


dehydroaustinol metabolic process

description: The chemical reactions and pathways involving dehydroaustinol.


name: positive regulation of heart rate by circulating norepinephrine

description: The process in which the secretion of norepinephrine into the bloodstream increases the rate of heart muscle contraction.


name: negative regulation of respiratory burst involved in inflammatory response

description: Any process that decreases the rate, frequency or extent of a phase of elevated metabolic activity, during which oxygen consumption increases made as a defense response ; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals.


diguanylate cyclase activity

description: Catalysis of the reaction: 2 GTP = cyclic di-3',5'-guanylate + 2 diphosphate + 2 H+.


name: epiboly involved in gastrulation with mouth forming second

description: The expansion of one cell sheet over other cells involved in deuterostomic gastrulation.


name: microgametophyte vegetative cell differentiation

description: The process in which a relatively unspecialized cell acquires specialized features of a microgametophyte. The microgametophyte vegetative cell gives rise to the pollen tube.


protein demannosylation

description: The removal of one or more mannose residues from a mannosylated protein.


name: positive regulation of lung blood pressure

description: The process that increases the force with which blood travels through the lungs.


L-threonylcarbamoyladenylate synthase

description: Catalysis of the reaction: L-threonine + ATP + bicarbonate = L-threonylcarbamoyladenylate + diphosphate + H2O.


histone catabolic process

description: The chemical reactions and pathways resulting in the breakdown of a histone protein by individual cells.


orcinol biosynthetic process

description: The chemical reactions and pathways resulting in the formation of orcinol (5-methyl-1,3-benzenediol), an aromatic compound derived from the fermentation of lichen and synthesized by some higher plants.


entry into reproductive diapause

description: The dormancy process that results in entry into reproductive diapause. Reproductive diapause is a form of diapause where the organism itself will remain fully active, including feeding and other routine activities, but the reproductive organs experience a tissue-specific reduction in metabolism, with characteristic triggering and releasing stimuli.


name: serotonin production involved in inflammatory response

description: The synthesis or release of serotonin following a stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels.


2,5-dihydroxypyridine metabolic process

description: The chemical reactions and pathways involving 2,5-dihydroxypyridine.


name: regulation of (1->3)-alpha-glucan metabolic process

description: Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds.


name: mesenchymal-epithelial cell signaling involved in lung development

description: Any process that mediates the transfer of information from a mesenchymal cell to an epithelial cell and contributes to the development of the lung.


forward locomotion

description: Anterior movement of an organism, following the direction of the head of the animal.


mammillary body development

description: The progression of the mammillary body over time from its initial formation until its mature state. The mammillary body is a protrusion at the posterior end of the hypothalamus that contains hypothalamic nuclei.


regulation of behavioral fear response

description: Any process that modulates the frequency, rate or extent of behavioral fear response.


name: negative regulation of male germ cell proliferation

description: Any process that stops, prevents or reduces the frequency, rate or extent of male germ cell proliferation.


name: afferent axon development in lateral line nerve

description: The process whose specific outcome is the progression of an afferent axon in a lateral line nerve over time from its formation to the mature structure. This process includes axonogenesis and pathfinding of the afferent axons in any lateral line nerve.


'de novo' GMP biosynthetic process

description: The chemical reactions and pathways resulting in the formation of guanosine 5'-monophosphate (GMP) through an inosine 5'-monophosphate (IMP) intermediate.


name: metanephric glomerular mesangial cell proliferation involved in metanephros development

description: The multiplication or reproduction of glomerular mesangial cells in the metanephros, resulting in the expansion of the population.


name: negative regulation of epidermis development

description: Any process that stops, prevents, or reduces the frequency, rate or extent of epidermis development.


peptidyl-arginine modification

description: The modification of peptidyl-arginine.


name: structural constituent of chitin-based cuticle

description: The action of a molecule that contributes to the structural integrity of a chitin-based cuticle. An example of this is found in Drosophila melanogaster.


name: central nervous system projection neuron axonogenesis

description: Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body towards target cells in a different central nervous system region.


chlorophyll cycle

description: A cyclic series of interconversions involving chlorophyll a, chlorophyll b and several chlorophyllide intermediates.


description: Catalysis of the reaction: a 3beta-hydroxysteroid-4alpha-carboxylate + NAD+ = a 3-oxosteroid + CO2 + NADH.


carbohydrate mediated signaling

category: biolink:Pathway biolink:OntologyClass biolink:BiologicalProcess biolink:Occurrent biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: The series of molecular signals mediated by the detection of carbohydrate.


lung basal cell differentiation

description: The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features of a mature basal cell found in the lung. Differentiation includes the processes involved in commitment of a cell to a specific fate. A basal cell is an epithelial stem cell.


name: minus-end specific microtubule depolymerization

description: The removal of tubulin heterodimers from the minus end of a microtubule.


name: arterial endothelial cell fate commitment

description: The commitment of a cell to an arterial endothelial cell fate and its capacity to differentiate into an arterial endothelial cell.


voltage-gated chloride channel activity

description: Enables the transmembrane transfer of a chloride ion by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.


name: decarboxylation-driven active transmembrane transporter activity

description: Primary active transport of a solute across a membrane driven by decarboxylation of a cytoplasmic substrate. Primary active transport is catalysis of the transport of a solute across a membrane, up the solute's concentration gradient, by binding the solute and undergoing a series of conformational changes. Transport works equally well in either direction and is driven by a primary energy source.


name: hydrolase activity, hydrolyzing N-glycosyl compounds

description: Catalysis of the hydrolysis of any N-glycosyl bond.


description: Catalysis of the reaction: phenanthrene-4,5-dicarboxylate + H+ = phenanthrene-4-carboxylate + CO2.


name: aromatic amino acid:proton symporter activity

description: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: aromatic amino acid(out) + H+(out) = aromatic amino acid(in) + H+(in).


name: regulation of sorocarp spore cell differentiation

description: Any process that modulates the frequency, rate or extent of sorocarp spore cell differentiation.


name: positive regulation of dopamine receptor signaling pathway

description: Any process that activates or increases the frequency, rate or extent of the dopamine receptor protein signaling pathway. A dopamine receptor signaling pathway is the series of molecular signals generated as a consequence of a dopamine receptor binding to one of its physiological ligands.


name: oxidoreductase activity, acting on other nitrogenous compounds as donors, iron-sulfur protein as acceptor

description: Catalysis of an oxidation-reduction (redox) reaction in which a nitrogenous group, excluding NH and NH2 groups, acts as a hydrogen or electron donor and reduces an iron-sulfur protein.


interleukin-23 production

description: The appearance of interleukin-23 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


name: pyloric antrum smooth muscle contraction

description: A process in which force is generated within gastric smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the widest part of the pylorus that is continuous with the body of the stomach.


name: regulation of establishment or maintenance of bipolar cell polarity regulating cell shape

description: Any process that modulates the frequency, rate or extent of establishment or maintenance of bipolar cell polarity regulating cell shape.


(S)-norcoclaurine synthase activity

description: Catalysis of the reaction: 4-(2-aminoethyl)benzene-1,2-diol + 4-hydroxyphenylacetaldehyde = (S)-norcoclaurine + H2O.


saponin metabolic process

description: The chemical reactions and pathways involving saponins, glycosides of plants in which the aglycan (sapogenin) group is a terpene or steroid and the sugar group is a glucose, a galactose, a pentose, a methylpentose or an oligosaccharide. Saponins are powerful surfactant agents and membrane active; they are, hence, toxic to animals on injection.


aspyridone B metabolic process

description: The chemical reactions and pathways involving aspyridone B.


description: Binding to 5-O-phosphono-alpha-D-ribofuranosyl diphosphate.


response to prostaglandin

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin stimulus.


name: carbon-oxygen lyase activity, acting on polysaccharides

description: Catalysis of the cleavage of a carbon-oxygen bond by the elimination of an alcohol from a polysaccharide.


cellular response to butyrate

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a butyrate stimulus.


name: specification of mesonephric proximal tubule identity

description: The process in which the proximal tubule of the mesonephric nephron acquires its identity.


name: adenosine 5'-(hexahydrogen pentaphosphate) catabolic process

description: The chemical reactions and pathways resulting in the breakdown of adenosine 5'-(hexahydrogen pentaphosphate).


description: Catalysis of the transfer, in a beta 1,3 linkage, of D-glucuronic acid (GlcUA) from UDP-D-glucuronic acid to N-acetyllactosamine (galactosyl beta-1,4-N-acetylglucosamine).


callus formation

description: The process by which a callus is formed at a wound site. A plant callus is a portion of plant tissue that consists of mass of undifferentiated plant cells. It consists primarily of parenchyma cells but possibly contains other cell types as the callus begins to differentiate.


regulation of oogonium development

description: Any process that modulates the frequency, rate or extent of oogonium development, a process that leads to the formation of a female gametangium of oomycetes, containing one or more gametes.


name: positive regulation of tonic skeletal muscle contraction

description: Any process that activates or increases the frequency, rate or extent of tonic skeletal muscle contraction.


diet induced thermogenesis

description: The process that results in increased metabolic rate in tissues of an organism. It is triggered by the detection of dietary excess. This process is achieved via signaling in the sympathetic nervous system.


response to acetylsalicylate

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aspirin (acetylsalicylate) stimulus. Aspirin is a non-steroidal anti-inflammatory drug with moA cyclooxygenase inhibitor activity.


name: microtubule anchoring at cell cortex of cell tip

description: Any process in which a microtubule is maintained in a specific location at the cell tip by attachment to the cell cortex.


cAMP metabolic process

description: The chemical reactions and pathways involving the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate).


name: regulation of cardioblast cell fate specification

description: Any process that mediates the specification of a cell into a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.


name: positive regulation of blood vessel branching

description: Any process that activates or increases the frequency, rate or extent of blood vessel branching.


description: Catalysis of the reaction: S-adenosyl-L-methionine + precorrin-3B = S-adenosyl-L-homocysteine + precorrin 4.


name: response to 1-oleoyl-sn-glycerol 3-phosphate

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 1-oleoyl-sn-glycerol 3-phosphate stimulus.


name: negative regulation of blood vessel morphogenesis

description: Any process that stops, prevents, or reduces the frequency, rate or extent of blood vessel morphogenesis.


pyrene 1,2-monooxygenase activity

description: Catalysis of the reaction: pyrene + O2 + 2 H+ + 2 e- = pyrene-1,2-oxide + H2O.


name: [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity

description: Catalysis of the reaction: [3-hydroxy-3-methylglutaryl-CoA reductase (NADPH)] + ATP = [3-hydroxy-3-methylglutaryl-CoA reductase (NADPH)] phosphate + ADP.


name: positive regulation of vulval development

description: Any process that activates or increases the frequency, rate or extent of development of the vulva. Vulval development is the process whose specific outcome is the progression of the egg-laying organ of female and hermaphrodite nematodes over time, from its formation to the mature structure. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed vulva in the adult.


sensory perception of gravity

description: The series of events required for an organism to receive a gravitational stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.


name: positive regulation of amyloid-beta clearance

description: Any process that activates or increases the frequency, rate or extent of amyloid-beta clearance.


description: Catalysis of the reaction: AH(2) + O2 + thiophene-2-carbonyl-CoA = 5-hydroxythiophene-2-carbonyl-CoA + A + H2O + H+.


mammary gland duct morphogenesis

description: The process in which anatomical structures of the mammary ducts are generated and organized. Mammary ducts are epithelial tubes that transport milk.


cellular response to dodecane

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dodecane stimulus.


description: Catalysis of the reaction: ATP + nicotinate ribonucleotide = diphosphate + deamido-NAD+.


mitochondrial nucleoid organization

description: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the mitochondrial nucleoid. The mitochondrial nucleoid is the region of a mitochondrion to which the DNA is confined.


pyridoxal metabolic process

description: The chemical reactions and pathways involving 3-hydroxy-5-(hydroxymethyl)-2-methyl-4-pyridinecarboxaldehyde, one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate.


name: detection of reduced oxygen by chemoreceptor signaling

description: The process in which information about the levels of oxygen are received and are converted to a molecular signal by chemoreceptors in the carotid bodies and the aortic bodies.


acid-CoA ligase (GDP-forming) activity

description: Catalysis of the reaction: a carboxylate + CoA + GTP = acyl-CoA + GDP + H+ + phosphate.


cellular response to acid chemical

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by the chemical structure of the anion portion of the dissociated acid (rather than the acid acting as a proton donor). The acid chemical may be in gaseous, liquid or solid form.


name: early neuron differentiation in forebrain

description: The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of neurons. Differentiation includes the processes involved in commitment of a cell to a specific fate.


name: regulation of gamma-aminobutyric acid secretion

description: Any process that modulates the frequency, rate or extent of the regulated release of gamma-aminobutyric acid.


erythritol kinase activity

description: Catalysis of the reaction: ATP + erythritol = D-erythritol 4-phosphate + ADP + 2 H+.


regulation of toluene metabolic process

description: Any process that modulates the frequency, rate or extent of toluene metabolic process.


pantetheine hydrolase activity

description: Catalysis of the reaction: (R)-pantetheine + H2O = (R)-pantothenate + cysteamine.


biuret amidohydrolase activity

description: Catalysis of the reaction: biuret + H2O = urea + CO2 + NH3.


description: Catalysis of the reaction: UDP-arabinose + a flavonol = UDP + a flavonol 3-O-D-arabinoside.


cupric ion binding

description: Binding to a cupric ion, copper(2+).


name: positive regulation of endocardial cushion cell differentiation

description: Any process that activates or increases the frequency, rate or extent of endocardial cushion cell differentiation.


amine sulfotransferase activity

description: Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + an amine = adenosine 3',5'-bisphosphate + a sulfamate.


name: negative regulation of anthocyanin metabolic process

description: Any process that stops, prevents, or reduces the frequency, rate or extent of chemical reactions and pathways involving anthocyanins.


S-glycoside metabolic process

description: The chemical reactions and pathways involving S-glycosides, any compound in which a glycosyl group has been substituted into a thiol group.


name: response to spindle assembly checkpoint signaling

description: A process that occurs in response to signals generated as a result of spindle assembly checkpoint signaling.


name: positive regulation of octopamine or tyramine signaling pathway

description: Any process that activates or increases the frequency, rate or extent of octopamine or tyramine signaling pathway.


name: negative regulation of granulosa cell apoptotic process

description: Any process that stops, prevents or reduces the frequency, rate or extent of granulosa cell apoptotic process.


name: regulation of plant-type cell wall organization or biogenesis

description: Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving plant-type cell wall organization or biogenesis. Plant-type cell wall organization or biogenesis is a process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cellulose- and pectin-containing cell wall.


name: cellular response to caloric restriction

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a of caloric restriction, insufficient food energy intake.


regulation of tyrosinase activity

description: Any process that modulates the activity of a tyrosinase enzyme.


name: glycerol-3-phosphate 1-dehydrogenase (NADP+) activity

description: Catalysis of the reaction: sn-glycerol 3-phosphate + NADP+ = D-glyceraldehyde 3-phosphate + H+ + NADPH.


description: Catalysis of the reaction: 2-hydroxy-2-methyl-1,3-dicarbonate + H+ = CO2 + L-lactate.


name: protein localization involved in establishment of planar polarity

description: Any process in which a protein is transported to, and/or maintained in, a specific location in a cell that contributes to the establishment of planar polarity.


name: positive regulation of conidiophore stalk development

description: Any process that activates or increases the frequency, rate or extent of conidiophore stalk development, a process that leads to the formation of a conidiophore stalk. The conidiophore stalk is part of a specialized hypha that extends aerially from the growth substrate and supports structures from which conidia, or asexual spores, develop.


description: Catalysis of the reaction: ent-sandaracopimaradien-3-beta-ol + NADPH + H+ + O2 = oryzalexin E + NADP + H2O.


name: negative regulation of uracil import across plasma membrane

description: Any process that stops, prevents or reduces the frequency, rate or extent of uracil import across plasma membrane.


name: d-4,5 unsaturated beta-glucuronyl hydrolase activity

description: Catalysis of the hydrolysis of the glycosidic bond in an unsaturated saccharide between the unsaturated glucuronyl residue at the nonreducing terminus and the saccharide linked to the residue.


amphid sensory organ development

description: The progression of the amphid sensory organ over time, from its formation to the mature structure. Amphid sensory organs are the sensory organs of nematodes.


thromboxane A2 signaling pathway

description: A G protein-coupled receptor signaling pathway initiated by thromboxane A2 binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.


name: myeloid dendritic cell differentiation involved in immune response

description: The process in which an immature myeloid dendritic cell acquires the specialized features of a mature myeloid dendritic cell as part of an immune response.


name: SA node cell-atrial cardiac muscle cell adhesion involved in cell communication

description: The attachment of SA node cardiomyocyte to an atrial cardiomyocyte via adhesion molecules that results in the cells being juxtaposed so that they can communicate.


synaptonemal complex organization

description: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a synaptonemal complex. A synaptonemal complex is a proteinaceous scaffold formed between homologous chromosomes during meiosis.


name: adhesion of symbiont to host via host extracellular matrix

description: The attachment of a symbiont to its host by binding to a component of the host extracellular matrix. The host is defined as the larger of the organisms involved in a symbiotic interaction.


AUG codon-amino acid adaptor activity

description: A triplet codon-amino acid adaptor activity that recognizes an AUG codon.


name: 2,4,4-trimethyl-3-oxopentanoyl-CoA 2-C-propanoyl transferase activity

description: Catalysis of the reaction: 2,4,4-trimethyl-3-oxopentanoyl-CoA + CoASH = pivalyl-CoA + propanoyl-CoA.


thyroid-hormone transaminase activity

description: Catalysis of the reaction: 2-oxoglutarate + 3,5,3'-triiodo-L-thyronine = 3,5,3'-triiodothyropyruvate + L-glutamate.


response to antineoplastic agent

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antineoplastic agent stimulus. An antineoplastic agent is a substance that inhibits or prevents the proliferation of neoplasms.


nitroalkane oxidase activity

description: Catalysis of the reaction: nitroalkane + H2O + O2 = an aldehyde or ketone + nitrite + H2O2.


metacyclogenesis

description: The morphological, biochemical and genetic changes that induce the differentiation of non-pathogenic parasites into pathogenic metacyclic parasites in the Trypanosomatidae species. The pathogenic parasites are known as metacyclic trypomastigotes in Trypanosoma and metacyclic promastigotes in Leishmania.


name: positive regulation of extrinsic apoptotic signaling pathway via death domain receptors

description: Any process that activates or increases the frequency, rate or extent of extrinsic apoptotic signaling pathway via death domain receptors.


name: general adaptation syndrome, behavioral process

description: The set of behavioral processes that occur as part of the general adaptation syndrome, the response of the body to a strong, stressful stimulus.


MHC class II protein complex binding

description: Binding to a class II major histocompatibility complex.


name: 3-methoxy-4-hydroxy-5-decaprenylbenzoic acid decarboxylase activity

description: Catalysis of the reaction: 3-methoxy-4-hydroxy-5-decaprenylbenzoic acid -> 2-methoxy-6-decaprenylphenol + CO2.


name: calcium-dependent protein serine/threonine kinase activity

description: Calcium-dependent catalysis of the reactions: ATP + a protein serine = ADP + protein serine phosphate; and ATP + a protein threonine = ADP + protein threonine phosphate.


sensory perception of light stimulus

description: The series of events required for an organism to receive a sensory light stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.


ajmaline biosynthetic process

description: The chemical reactions and pathways resulting in the formation of ajmaline.


name: regulation of larval somatic muscle development

description: Any process that modulates the rate, frequency or extent of larval somatic muscle development.


carnitine metabolic process

description: The chemical reactions and pathways involving carnitine (hydroxy-trimethyl aminobutyric acid), a compound that participates in the transfer of acyl groups across the inner mitochondrial membrane.


name: trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission

description: Cell-cell signaling between presynapse and postsynapse, mediated by transynaptic protein complexes, that modulates the synaptic transmission properties of the synapse.


Wnt receptor recycling

description: The process that results in the return of a Wnt receptor to an active state at the plasma membrane. An active state is when the receptor is ready to receive a Wnt signal. Internalized Wnt receptors can be recycled to the plasma membrane or sorted to lysosomes for protein degradation.


peptidyl-methionine modification

description: The modification of peptidyl-methionine.


trigeminal nerve morphogenesis

description: The process in which the anatomical structure of the trigeminal nerve is generated and organized. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae.


name: ursodeoxycholate 7-beta-dehydrogenase (NAD+) activity

description: Catalysis of the reaction: NAD+ + ursodeoxycholate = 7-oxolithocholate + H+ + NADH.


name: cellular organohalogen metabolic process

description: The chemical reactions and pathways involving organohalogen compounds, as carried out by individual cells.


acrylonitrile metabolic process

description: The chemical reactions and pathways involving acrylonitrile, a colorless, volatile liquid with a pungent odor. Acrylonitrile is used in the production of acrylic fibers, plastics, and synthetic rubbers.


adenine salvage

description: Any process that generates adenine, 6-aminopurine, from derivatives of it without de novo synthesis.


name: 6-sulfoquinovose(1-) catabolic process to 3-sulfopropanediol(1-)

description: The chemical reactions and pathways resulting in the breakdown of 6-sulfoquinovose(1-) resulting in the formation of glycerone phosphate (DHAP) and 3-sulfopropanediol(1-).


peptidyl-cysteine deglycation

description: The removal of a sugar or dicarbonyl from a cysteine residue of a glycated protein.


response to glycine

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glycine stimulus.


description: Catalysis of the reaction: trans-cinnamate + UDP-D-glucose = 1-O-trans-cinnamoyl-beta-D-glucopyranose + UDP.


name: regulation of cell wall pectin metabolic process

description: Any process that modulates the frequency, rate or extent of cell wall pectin metabolic process.


acetate metabolic process

description: The chemical reactions and pathways involving acetate, the anion of acetic acid.


serotonin catabolic process

description: The chemical reactions and pathways resulting in the breakdown of serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties.


3-hydroxykynureninase activity

description: Catalysis of the reaction: L-3-hydroxykynurenine + H2O = 3-hydroxyanthranilate + L-alanine.


name: positive regulation of apoptotic process involved in mammary gland involution

description: Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process of mammary epithelial cells during mammary gland involution.


description: Catalysis of the reaction: UDP-N-acetyl-alpha-D-glucosamine + ditrans,octacis-undecaprenyl phosphate = UMP + N-acetyl-alpha-D-glucosaminyldiphospho-ditrans,octacis-undecaprenol.


ascus development

description: The process that leads to the development of ascus, a sac-like structure produced by fungi of the phylum Ascomycota (sac fungi) in which sexually produced spores (ascospores), usually four or eight in number, are formed.


name: positive regulation of cell proliferation involved in heart morphogenesis

description: Any process that activates or increases the frequency, rate or extent of cell proliferation involved in heart morphogenesis.


name: B cell antigen processing and presentation

description: The process in which a B cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex.


name: regulation of myeloid leukocyte mediated immunity

description: Any process that modulates the frequency, rate, or extent of myeloid leukocyte mediated immunity.


name: corticospinal neuron axon guidance through the basilar pons

description: The process in which the migration of an axon growth cone of a pyramidal cell that is part of the corticospinal tract is directed after exiting the cerebral peduncle through the basilar pons in response to a combination of attractive and repulsive cues.


name: chondroitin sulfate proteoglycan metabolic process

description: The chemical reactions and pathways involving chondroitin sulfate proteoglycan, any glycoprotein whose glycosaminoglycan units are chondroitin sulfate. Chondroitin sulfates are a group of 10-60 kDa glycosaminoglycans, widely distributed in cartilage and other mammalian connective tissues; the repeat units consist of beta-(1,4)-linked D-glucuronyl beta-(1,3)-N-acetyl-D-galactosamine sulfate.


name: mRNA cleavage and polyadenylation specificity factor complex assembly

description: The aggregation, arrangement and bonding together of a set of components to form the mRNA cleavage and polyadenylation specificity factor complex.


description: Catalysis of the reaction: GDP-beta-L-galactose + alpha-D-mannose 1-phosphate = GDP-alpha-D-mannose + beta-L-galactose-1-phosphate.


name: positive regulation of cellular response to transforming growth factor beta stimulus

description: Any process that activates or increases the frequency, rate or extent of cellular response to transforming growth factor beta stimulus.


polyterpenoid biosynthetic process

description: The chemical reactions and pathways resulting in the formation of polyterpenoid compounds, terpenoids with more than eight isoprene units.


kynureninase activity

description: Catalysis of the reaction: L-kynurenine + H2O = anthranilate + L-alanine.


procambium histogenesis

description: The formation of the primary meristem or meristematic tissue that gives rise to the primary vascular tissue.


name: stress-activated protein kinase signaling cascade

description: The series of molecular signals in which a stress-activated protein kinase (SAPK) cascade relays a signal.


description: Catalysis of the reaction: N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide + L-glutamine + ATP + H2O = 2-(formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine + L-glutamate + ADP + 2 H+ + phosphate.


polyprenol biosynthetic process

description: The chemical reactions and pathways resulting in the formation of polyprenols, prenols with more than 4 isoprenoid residues, which may be all-trans, or a mixture of cis and trans.


name: alpha-D-ribose 1-methylphosphonate 5-phosphate C-P-lyase activity

description: Catalysis of the reaction: alpha-D-ribose 1-methylphosphonate 5-phosphate = alpha-D-ribose 1,2-cyclic phosphate 5-phosphate + methane.


name: protein-N(PI)-phosphohistidine-galactitol phosphotransferase system transmembrane transporter activity

description: Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + galactitol(out) = protein histidine + galactitol phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.


name: forebrain anterior/posterior pattern specification

description: The creation of specific areas of progenitor domains along the anterior-posterior axis of the developing forebrain.


monensin A metabolic process

description: The chemical reactions and pathways involving monensin A.


prostaglandin E receptor activity

description: Combining with prostaglandin E (PGE(2)) to initiate a change in cell activity.


name: regulation of vasoconstriction by epinephrine

description: Any process that modulates the frequency, rate or extent of reductions in the diameter of blood vessels as a result of secretion of epinephrine into the bloodstream or released by nerve endings.


name: sodium:chloride symporter activity

description: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Na+(out) + Cl-(out) = Na+(in) + Cl-(in).


tyrosine N-monooxygenase activity

description: Catalysis of the reaction: tyrosine + O2 + NADPH + H+ = N-hydroxytyrosine + NADP+ + H2O.


menthol metabolic process

description: The chemical reactions and pathways involving menthol, the monoterpene 2-isopropyl-5-methylcyclohexanol.


siroheme biosynthetic process

description: The chemical reactions and pathways resulting in the formation of siroheme, a tetrahydroporphyrin with adjacent, reduced pyrrole rings.


name: brain-derived neurotrophic factor receptor activity

description: Combining with a brain-derived neurotrophic factor and transmitting the signal across the plasma membrane to initiate a change in cell activity.


name: anti-Mullerian hormone receptor activity

description: Combining with anti-Mullerian hormone to initiate a change in cell activity.


name: polarized epithelial cell differentiation

description: The process in which a relatively unspecialized cell acquires specialized features of a polarized epithelial cell. The polarized epithelial cell can be any of the cells within an epithelium where the epithelial sheet is oriented with respect to the planar axis.


name: monocyte chemotactic protein-1 production

description: The appearance of monocyte chemotactic protein-1 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


response to L-glutamine

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-glutamine stimulus.


name: regulation of cellular response to iron ion starvation

description: Any process that modulates the frequency, rate or extent of cellular response to iron ion starvation.


name: chlorophyll a biosynthetic process via phytyl diphosphate

description: The chemical reactions and pathways leading to the formation of chlorophyll a, via the intermediate phytyl diphosphate.


name: testosterone 17-beta-dehydrogenase (NADP+) activity

description: Catalysis of the reaction: NADP+ + testosterone = NADPH + H+ + androst-4-ene-3,17-dione.


description: Catalysis of the reaction: delta1-piperideine-6-carboxylate + NAD+ + 2 H2O = 2-aminoadipate + NADH + H+. Delta1-piperideine-6-carboxylate is also known as 2,3,4,5-tetrahydropyridine-2-carboxylate.


response to bronchodilator

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bronchodilator stimulus. A bronchodilator is a chemical that causes an increase in the expansion of a bronchus or bronchial tubes.


name: axon ensheathment in central nervous system

description: The process in which a glial cell membrane closes around an axon in the central nervous system. This can be a myelinating or a non-myelinating neuron-glial interaction.


name: positive regulation of anterograde synaptic vesicle transport

description: Any process that activates or increases the frequency, rate or extent of anterograde synaptic vesicle transport.


colneleate synthase activity

description: Catalysis of the reaction: 9(S)-HPODE = colneleate + H2O.


name: positive regulation of epiboly involved in gastrulation with mouth forming second

description: Any process that activates or increases the frequency, rate or extent of epiboly involved in gastrulation with mouth forming second.


geranyl-diphosphate cyclase activity

description: Catalysis of the reaction: geranyl diphosphate = (2S)-bornyl diphosphate.


description: Catalysis of the reaction: UDP-galactose + N-acetylglucosamine = galactose-beta-1,3-N-acetylglucosamine + UDP.


RNA-protein covalent cross-linking

description: The formation of a covalent cross-link between RNA and a protein.


name: negative regulation of filamentous growth of a population of unicellular organisms in response to heat

description: Any process that stops, prevents or reduces the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to heat.


dehydroscoulerine synthase activity

description: Catalysis of the reaction: (S)-scoulerine + O2 = dehydroscoulerine + hydrogen peroxide + H+.


renal artery morphogenesis

description: The process in which the anatomical structure of a renal artery is generated and organized. Renal arteries supply the kidneys with blood.


name: modulation by symbiont of host response to abiotic stimulus

description: Any process in which an organism modulates a change in the state or activity of a host cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abiotic (non-living) stimulus. The host is defined as the larger of the organisms involved in a symbiotic interaction.


pectin biosynthetic process

description: The chemical reactions and pathways resulting in the formation of pectin, a polymer containing a backbone of alpha-1,4-linked D-galacturonic acid residues.


name: regulation of TRAIL-activated apoptotic signaling pathway

description: Any process that modulates the frequency, rate or extent of TRAIL-activated apoptotic signaling pathway.


name: regulation of neurotransmitter transport

description: Any process that modulates the frequency, rate or extent of the directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


name: leukocyte chemotaxis involved in immune response

description: The movement of an immune cell in response to an external stimulus a part of an immune response.


name: negative regulation of myeloid cell differentiation

description: Any process that stops, prevents, or reduces the frequency, rate or extent of myeloid cell differentiation.


glycol catabolic process

description: The chemical reactions and pathways resulting in the breakdown of glycol, a diol in which the two hydroxy groups are on different carbon atoms, usually but not necessarily adjacent.


cardiac right atrium morphogenesis

description: The process in which the right cardiac atrium is generated and organized.


name: positive regulation of microglial cell activation

description: Any process that activates or increases the frequency, rate or extent of microglial cell activation.


glutamine biosynthetic process

description: The chemical reactions and pathways resulting in the formation of glutamine, 2-amino-4-carbamoylbutanoic acid.


description: Catalysis of the reaction: tRNA guanine + 7-cyano-7-deazaguanine = tRNA 7-cyano-7-deazaguanine + guanine.


type B pancreatic cell development

description: The process whose specific outcome is the progression of a type B pancreatic cell over time, from its formation to the mature structure. A type B pancreatic cell is a cell located towards center of the islets of Langerhans that secretes insulin.


response to gemcitabine

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gemcitabine stimulus. Gemcitabine is a 2'-deoxycytidine having geminal fluoro substituents in the 2'-position, and is used as a drug in the treatment of various carcinomas.


lactone metabolic process

description: The chemical reactions and pathways involving lactone.


name: symbiont-mediated disruption of host extracellular matrix

description: The process in which an organism effects a change that impairs the structure or function of the host extracellular matrix.


NADH peroxidase activity

description: Catalysis of the reaction: H2O2 + NADH + H+ = 2 H2O + NAD+.


description: Catalysis of the reaction: 2-heptyl-4-quinolone + NADH + O2 + H+ = 2-heptyl-3-hydroxy-4-quinolone + NAD + H2O.


name: fungal-type cell wall (1->3)-beta-D-glucan biosynthetic process

description: The chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds, found in fungal cell walls.


name: glutamate catabolic process to 2-oxoglutarate

description: The chemical reactions and pathways resulting in the breakdown of glutamate into other compounds, including 2-oxoglutarate.


name: symbiont-mediated perturbation of host signal transduction pathway

description: A process in which a symbiont alters or subverts a signal transduction pathway in its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.


name: regulation of immature T cell proliferation

description: Any process that modulates the frequency, rate or extent of immature T cell proliferation.


name: granulocyte-macrophage colony-stimulating factor signaling pathway

description: The series of molecular signals initiated by the binding of the cytokine granulocyte macrophage colony-stimulating factor (GM-CSF) to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. GM-CSF binds to a heterodimer receptor (CSF2R) consisting of an alpha ligand-binding subunit, and a common beta subunit that is shared with other cytokine receptors.


threonine-tRNA ligase activity

description: Catalysis of the reaction: ATP + L-threonine + tRNA(Thr) = AMP + diphosphate + L-threonyl-tRNA(Thr).


name: heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process

description: The chemical reactions and pathways resulting in the formation of polysaccharide chain component of heparan sulfate proteoglycan.


glutaminase activity

description: Catalysis of the reaction: L-glutamine + H2O = L-glutamate + NH3.


peptidyl-lysine propionylation

description: The propionylation of peptidyl-lysine.


description: Catalysis of the reaction: 5 H+ + NADH + a menaquinone = 4 H+ + NAD + a menaquinol.


response to environmental enrichment

description: Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the provision of a combination of complex inanimate and social stimulations in the organism's housing environment.


cellular response to anisomycin

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an anisomycin stimulus.


labial disc development

description: Progression of the labial imaginal disc over time, from its initial formation through to its metamorphosis to form adult structures including parts of the proboscis.


cocaine biosynthetic process

description: The chemical reactions and pathways resulting in the formation of cocaine, an alkaloid obtained from the dried leaves of the shrub Erythroxylon coca. It is a cerebral stimulant and narcotic.


name: formation of arbuscule for nutrient acquisition

description: The assembly of an arbuscule, a fine, tree-like hyphal symbiont structure projected into the host cell for the purpose of obtaining nutrients. The host is defined as the larger of the organisms involved in a symbiotic interaction.


name: DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity

description: Catalysis of a DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined, driven by ATP hydrolysis. The enzyme changes the linking number in multiples of 2.


description: Catalysis of the reaction: 4-hydroxy-2-ketopimelate = succinate semialdehyde + pyruvate.


8-oxoguanine deaminase activity

description: Catalysis of the reaction: H+ + 7,8-dihydro-8-oxoguanine + H2O = 7,9-dihydro-1H-purine-2,6,8(3H)-trione + ammonium.


gluconate dehydrogenase activity

description: Catalysis of the reaction: D-gluconate + NADP+ = dehydro-D-gluconate + NADPH + H+.


Kdo2-lipid A biosynthetic process

description: The chemical reactions and pathways resulting in the formation of Kdo2-lipid A, a lipopolysaccharide (LPS) component.


compound eye cone cell fate commitment

description: The process in which the cone cells of the compound eye, the lens-secreting cells in the ommatidia, adopt pathways of differentiation that lead to the establishment of their distinct cell type.


semicircular canal formation

description: The developmental process pertaining to the initial formation of the semicircular canal from the otic vesicle. This process begins with the regionalization of the vesicle that specifies the area where the vesicles will form and continues through the process of fusion which forms the initial tubes.


description: Catalysis of the reaction: N-sulfo-D-glucosamine + H2O = D-glucosamine + sulfate.


regulation of root meristem growth

description: Any process involved in maintaining the size and shape of a root meristem.


crystal cell differentiation

description: The process in which a hemocyte precursor cell acquires the characteristics of a crystal cell, a class of cells that contain crystalline inclusions and are involved in the melanization of pathogenic material in the hemolymph.


description: Catalysis of the reaction: 12-hydroxydihydrochelirubine + S-adenosyl-L-methionine(1+) = S-adenosyl-L-homocysteine + dihydromacarpine + H+.


vasodilation in another organism

description: A process by which an organism causes vasodilation of blood vessels, usually causing a reduction in blood pressure, in another organism.


acetaldehyde biosynthetic process

description: The chemical reactions and pathways resulting in the formation of acetaldehyde, a colorless, flammable liquid intermediate in the metabolism of alcohol.


all-trans undecaprenol kinase activity

description: Catalysis of the reaction: ATP + undecaprenol + all-trans-undecaprenyl phosphate + ADP + H+.


arabitol metabolic process

description: The chemical reactions and pathways involving arabitol, the pentitol derived from arabinose or lyxose by reduction of the aldehyde group.


name: skeletal muscle satellite cell fate determination

description: The process in which a cell becomes capable of differentiating autonomously into a skeletal muscle satellite cell regardless of its environment; upon determination, the cell fate cannot be reversed.


regulation of response to furfural

description: Any process that modulates the frequency, rate or extent of response to furfural.


name: inositol heptakisphosphate 6-kinase activity

description: Catalysis of the reaction: ATP + 5-diphospho-1D-myo-inositol (1,2,3,4,6)pentakisphosphate = 5,6-bisdiphosphoinositol-1D-myoinositol (1,2,3,4)tetrakisphosphate.


butanal dehydrogenase activity

description: Catalysis of the reaction: butanal + CoA + NAD(P)+ = butanoyl-CoA + NAD(P)H + H+.


alditol phosphate metabolic process

description: The chemical reactions and pathways involving alditol phosphates, any phosphorylated polyhydric alcohol derived from the acyclic form of a monosaccharide by reduction of its aldehyde or keto group to an alcoholic group.


isoquinoline 1-oxidoreductase activity

description: Catalysis of the reaction: A + H2O + isoquinoline = AH(2) + isoquinolin-1(2H)-one.


intracellular polyamine homeostasis

description: A homeostatic process involved in the maintenance of a steady state level of polyamine within a cell.


rhamnose catabolic process

description: The chemical reactions and pathways resulting in the breakdown of rhamnose, the hexose 6-deoxy-L-mannose.


name: proton motive force-driven motor activity

description: A motor activity driven by an electrochemical proton gradient (proton-motive force). PMF-driven motors are used by bacterial flagella.


thiamine diphosphate catabolic process

description: The chemical reactions and pathways resulting in the breakdown of thiamine diphosphate, a derivative of thiamine (vitamin B1) which acts as a coenzyme in a range of processes including the Krebs cycle.


sleep homeostasis

description: A homeostatic process in which the drive for sleep increases sleep propensity with prolonged wakefulness.


maintenance of root meristem identity

description: The process in which an organism retains a population of root meristem cells, preventing the commitment of all stem cell progeny to a differentiated cell fate.


vulval cell fate specification

description: The process in which a cell becomes capable of differentiating autonomously into a nematode vulval cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed adult vulva, which is the egg-laying organ of female and hermaphrodite nematodes.


ABC-type azole transporter activity

description: Enables the transfer of azoles, heterocyclic compound found in many biologically important substances, from one side of a membrane to the other according to the reaction: ATP + H2O + azole(in) = ADP + phosphate + azole(out).


regulation of CD40 signaling pathway

description: Any process that modulates the frequency, rate or extent of signaling via the CD40 signaling pathway.


response to vitamin

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin stimulus.


name: corticospinal neuron axon guidance through the cerebral cortex

description: The process in which the migration of an axon growth cone of a pyramidal cell that is part of the corticospinal tract is directed from its cell body in layer V through the cerebral cortex in response to a combination of attractive and repulsive cues.


name: regulation of muscle filament sliding speed involved in regulation of the velocity of shortening in skeletal muscle contraction

description: Any process that modulates the velocity of muscle filament sliding, and consequently contributes to the regulation of the velocity of shortening of skeletal muscle contraction.


ATP-dependent peptidase activity

description: Catalysis of the hydrolysis of peptide bonds, driven by ATP hydrolysis.


acetylcholine receptor activity

description: Combining with an acetylcholine receptor ligand and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


L-amino-acid dehydrogenase activity

description: Catalysis of the reaction: an L-amino acid + H2O + NAD+ = a 2-oxo acid + NH3 + NADH.


D-xylose reductase (NADPH) activity

description: Catalysis of the reaction: D-xylitol + NADP+ = D-xylose + NADPH + H+.


description: Catalysis of the reaction: N1-aminopropylagmatine + H2O = spermidine + urea.


name: negative regulation of autophagosome size

description: Any process that reduces autophagosome size.


peptide antigen stabilization

description: Any process involved in maintaining the structure and integrity of a peptide antigen and preventing it from being degraded.


asexual sporulation

description: The formation of spores derived from the products of an asexual cell division. Examples of this process are found in bacteria and fungi.


name: regulation of hypoxia-inducible factor-1alpha signaling pathway

description: Any process that modulates the frequency, rate or extent of hypoxia-inducible factor-1alpha signaling pathway.


name: embryo development ending in seed dormancy

description: The process whose specific outcome is the progression of the embryo over time, from zygote formation to the end of seed dormancy. An example of this process is found in Arabidopsis thaliana.


flavanol binding

description: Binding to a flavanol.


name: ferric triacetylfusarinine C transmembrane transporter activity

description: Enables the transfer of ferric triacetylfusarinine C from one side of a membrane to the other.


cell wall repair

description: A process of cell wall organization that results in the restoration of the cell wall following damage.


kinetochore binding

description: Binding to a kinetochore, a proteinaceous structure on a condensed chromosome, beside the centromere, to which the spindle fibers are attached.


description: Catalysis of the reaction: (E)-nerolidol + NADPH + O2 = (3E)-4,8-dimethylnona-1,3,7-triene + NADP+ + 2 H2O. It is unknown whether this reaction proceeds by the direct release of the 4-carbon compound but-1-en-3-one, or whether the substrate is first degraded to C11-geranylacetone and then cleaved to produce (3E)-4,8-dimethylnona-1,3,7-triene (DMNT) and acetone.


fructose-bisphosphate aldolase activity

description: Catalysis of the reaction: beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate.


name: corticotropin hormone secreting cell development

description: The process whose specific outcome is the progression of a corticotropic hormone secreting cell over time, from its formation to the mature structure. An corticotropic hormone secreting cell is a basophil cell of the anterior pituitary that produces corticotropin.


D-amino acid catabolic process

description: The chemical reactions and pathways resulting in the breakdown of D-amino acids, the D-enantiomers of amino acids.


diuretic hormone receptor activity

description: Combining with a diuretic hormone and transmitting the signal to initiate a change in cell activity.


name: deoxyribose 1,5-bisphosphate biosynthetic process

description: The chemical reactions and pathways resulting in the formation of deoxyribose 1,5-bisphosphate, the diphosphorylated sugar 1,5-diphospho-2-deoxyribose.


name: positive regulation of trophectodermal cell proliferation

description: Any process that activates or increases the frequency, rate or extent of trophectodermal cell proliferation.


name: regulation of (+)-kotanin biosynthetic process

description: Any process that modulates the frequency, rate or extent of (+)-kotanin biosynthetic process.


antigenic variation

description: A process by which a symbiont evades the host adaptive immune response by changing antigenic determinants on the symbiont surface that are exposed to host antibodies.


peroxynitrite reductase activity

description: Catalysis of the reaction: [protein]-dithiol + ONOO- = [protein]-disulfide + NO2- + H2O.


name: extraction of mislocalized protein from ER membrane

description: The removal of a mislocalized protein from the endoplasmic reticulum (ER) membrane.


selenocysteine-tRNA ligase activity

description: Catalysis of the reaction: tRNASec + L-Ser + ATP = Ser-tRNASec + AMP + diphosphate.


name: CD4-positive, alpha-beta T cell proliferation

description: The expansion of a CD4-positive, alpha-beta T cell population by cell division.


name: archaeal-type flagellum-dependent cell motility

description: Cell motility due to the motion of one or more archaeal-type flagella. An archaeal-type flagellum (also called archaellum) is a non-membrane-bounded organelle superficially similar to a bacterial-type flagellum, but having a different molecular structure and lacking a central channel.


name: positive regulation of chemotaxis to cAMP by DIF-2

description: Any process that increases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of DIF-2. DIF-2 is a chlorinated alkylphenone.


name: genital disc sexually dimorphic development

description: The sex-specific patterns of primoridia growth and differentiation in the genital imaginal disc. The anal primordium of the genital disc develops in both sexes, but depending on the genetic sex gives rise to either male or female analia. Depending on the genetic sex, only one of the two genital primordia develop. In females the female genital primordium develops and gives rise to the female genitalia whereas the male primordium is repressed. Conversely, in males the male genital primordium develops and gives rise to the male genitalia whereas the female genital primordium is repressed.


name: regulation of cellodextrin metabolic process

description: Any process that modulates the frequency, rate or extent of cellodextrin metabolic process.


proanthocyanidin biosynthetic process

description: The chemical reactions and pathways resulting in the formation of proanthocyanidin.


intramolecular oxidoreductase activity

description: Catalysis of an oxidation-reduction (redox) reaction in which the hydrogen donor and acceptor are the same molecule, and no oxidized product appears.


protein localization to postsynapse

description: Any process in which a protein is transported to, and/or maintained at the postsynapse, the part of a synapse that is part of the post-synaptic cell.


name: regulation of nurse cell apoptotic process

description: Any process that modulates the frequency, rate or extent of nurse cell apoptotic process.


name: imidazole-containing compound metabolic process

description: The chemical reactions and pathways involving imidazoles, five-membered organic heterocycle containing two nitrogen atoms at positions 1 and 3, or any of its derivatives; compounds containing an imidazole skeleton.


name: negative regulation of lipid catabolic process

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of lipids.


prostate gland development

description: The process whose specific outcome is the progression of the prostate gland over time, from its formation to the mature structure. The prostate gland is a partly muscular, partly glandular body that is situated near the base of the mammalian male urethra and secretes an alkaline viscid fluid which is a major constituent of the ejaculatory fluid.


chitobiose phosphorylase activity

description: Catalysis of the reaction: chitobiose + phosphate = N-acetyl-D-glucosamine + N-acetyl-alpha-D-glucosamine 1-phosphate. This reaction is the phosphorolysis of chitobiose, (GlcNAc)2, a dimer of beta-(1->4) linked glucosamine units.


gap junction assembly

description: Assembly of gap junctions, which are found in most animal tissues, and serve as direct connections between the cytoplasms of adjacent cells. They provide open channels through the plasma membrane, allowing ions and small molecules (less than approximately a thousand daltons) to diffuse freely between neighboring cells, but preventing the passage of proteins and nucleic acids.


name: maturation of 5.8S rRNA from tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, 2S rRNA, LSU-rRNA)

description: Any process involved in the maturation of a precursor 5.8S ribosomal RNA (rRNA) molecule into a mature 5.8S rRNA molecule from the pre-rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, the 8.8S rRNA, the 2S rRNA, and the Large Subunit (LSU) in that order from 5' to 3' along the primary transcript.


description: Catalysis of the reaction: a long-chain fatty aldehyde + CoA + NADP+ = a long-chain fatty acyl-CoA + NADPH.


diacylglycerol transacylase activity

description: Catalysis of the reaction: 2 a 1,2-diacyl-sn-glycerol = a triacyl-sn-glycerol + a 2-monoglyceride.


name: membrane fusion involved in acrosome reaction

description: The fusion of the plasma membrane of the sperm with the outer acrosomal membrane.


intergenic mRNA trans splicing

description: The joining together of two independently transcribed RNAs from two different genes, each of which also produces mRNA(s) via cis-splicing.


regulation of peroxisome size

description: Any process that modulates the volume of a peroxisome, a small, membrane-bounded organelle that uses dioxygen (O2) to oxidize organic molecules.


pullulan binding

description: Binding to pullulan.


regulation of hair follicle maturation

description: Any process that modulates the frequency, rate or extent of hair follicle maturation.


phosphatidic acid transfer activity

description: Removes a phosphatidic acid from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle. Phosphatidic acid refers to a glycophospholipids with, in general, a saturated fatty acid bonded to carbon-1, an unsaturated fatty acid bonded to carbon-2, and a phosphate group bonded to carbon-3.


description: The chemical reactions and pathways resulting in the formation of N-acetylneuraminate, the anion of 5-(acetylamino)-3,5-dideoxy-D-glycero-D-galacto-non-3-ulosonic acid.


cellulose biosynthetic process

description: The chemical reactions and pathways resulting in the formation of cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation.


name: negative regulation of smooth muscle cell proliferation

description: Any process that stops, prevents or reduces the rate or extent of smooth muscle cell proliferation.


geranoyl-CoA carboxylase activity

description: Catalysis of the reaction: ATP + bicarbonate + geranoyl-CoA = 3-(4-methylpent-3-en-1-yl)pent-2-enedioyl-CoA + ADP + 2 H+ + phosphate.


name: negative regulation of atrichoblast fate specification

description: Any process that suppresses atrichoblast fate specification.


ABC-type transporter activity

description: Primary active transporter characterized by two nucleotide-binding domains and two transmembrane domains. Uses the energy generated from ATP hydrolysis to drive the transport of a substance across a membrane.


name: negative regulation of establishment of Sertoli cell barrier

description: Any process that stops, prevents or reduces the frequency, rate or extent of establishment of Sertoli cell barrier.


response to epidermal growth factor

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an epidermal growth factor stimulus.


serous membrane development

description: The process whose specific outcome is the progression of a serous membrane over time, from its formation to the mature structure.


cyclic-di-AMP binding

description: Binding to a cyclic di-AMP nucleotide.


dark adaptation

description: The process by which the rods of the retina gradually become fully responsive to dim light when no longer exposed to bright light.


name: small RNA 2'-O-methyltransferase activity

description: Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the oxygen atom of a nucleoside residue in a small RNA molecule. Reaction: S-adenosyl-L-methionine + small RNA = S-adenosyl-L-homocysteine + small RNA containing a 3'-terminal 2'-O-methylnucleotide.


name: G protein-coupled GABA receptor activity

description: Combining with the amino acid gamma-aminobutyric acid (GABA, 4-aminobutyrate) and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.


olefinic compound metabolic process

description: The chemical reactions and pathways involving an olefinic compound, any compound which contains a carbon-carbon double bond (aka C=C).


description: Catalysis of the reaction: 5,10-methylenetetrahydrofolate + dCMP = 2'-deoxy-5-methyl-5'-cytidylate + 7,8-dihydrofolate.


tatiopterin metabolic process

description: The chemical reactions and pathways involving tatiopterin.


maternal placenta development

description: Maternally driven process whose specific outcome is the progression of the placenta over time, from its formation to the mature structure. The placenta is an organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin.


superior olivary nucleus development

description: The process whose specific outcome is the progression of the superior olivary nucleus over time, from its formation to the mature structure. In mice, the superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound.


maintenance of floral meristem identity

description: The process in which an organism retains a population of floral meristem cells, preventing the commitment of all stem cell progeny to a differentiated cell fate.


name: positive regulation of mitotic recombination-dependent replication fork processing

description: Any process that activates or increases the frequency, rate or extent of mitotic recombination-dependent replication fork processing. Regulation of mitotic recombination prevents recombination between inappropriate homologous sequences. Proteins involved in homologous recombination are required for replication restart.


altronate dehydratase activity

description: Catalysis of the reaction: D-altronate = 2-dehydro-3-deoxy-D-gluconate + H2O.


name: symbiont defense to host-produced jasmonic acid

description: Any process in which a symbiont modulates the frequency, rate or extent of the jasmonic acid-mediated defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.


adenosine nucleosidase activity

description: Catalysis of the reaction: adenosine + H2O = D-ribose + adenine.


name: spliceosomal conformational changes to generate catalytic conformation

description: Structural rearrangements of the spliceosome complex, containing RNA to be spliced, to generate a catalytic conformation.


atrial cardiac myofibril assembly

description: The process whose specific outcome is the progression of the atrial cardiac myofibril over time, from its formation to the mature structure. A cardiac myofibril is a myofibril specific to cardiac muscle cells.


name: regulation of L-arginine import across plasma membrane

description: Any process that modulates the frequency, rate or extent of L-arginine import across plasma membrane.


nitrogenase (flavodoxin) activity

description: Catalysis of the reaction: 6 reduced flavodoxin + 6 H+ + N2 + n ATP = 6 oxidized flavodoxin + 2 NH3 + n ADP + n phosphate.


carotene epsilon hydroxylase activity

description: Catalysis of the reaction: a carotene + NADPH + O2 + H+ = a beta-ring hydroxylcarotene + NADP+ + H2O. Adds a hydroxyl group to the epsilon ring of the alpha-carotene.


glomerulus morphogenesis

description: The process in which the anatomical structures of the glomerulus are generated and organized. The glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney.


description: Cytolysis of target cells by natural killer cells, eosinophils, neutrophils, monocytes, or macrophages following engagement of antibodies bound to the target cells by Fc receptors on the effector cells.


name: negative regulation of long-term synaptic potentiation

description: Any process that stops, prevents or reduces the frequency, rate or extent of long-term synaptic potentiation.


name: negative regulation of plant organ morphogenesis

description: Any process that stops, prevents or reduces the frequency, rate or extent of plant organ morphogenesis.


name: post-anaphase microtubule array organization

description: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly ofa post-anaphase microtubule array.


L-dopa decarboxylase activity

description: Catalysis of the reaction: L-dopa + H+ = CO2 + dopamine.


name: epithelial cell proliferation involved in lung bud dilation

description: The multiplication or reproduction of epithelial cells that contribute to the radial growth of a lung bud.


name: tRNA (uridine) methyltransferase activity

description: Catalysis of the transfer of a methyl group from a donor to a uracil residue in a tRNA molecule.


peptidylglycine monooxygenase activity

description: Catalysis of the reaction: peptidyl-glycine + ascorbate + O2 = peptidyl(2-hydroxyglycine) + dehydroascorbate + H2O.


name: negative regulation of synaptic plasticity

description: A process that decreases synaptic plasticity, the ability of synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers.


dorsal/ventral neural tube patterning

description: The process in which the neural tube is regionalized in the dorsoventral axis.


name: immune response-inhibiting signal transduction

description: The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately leading to inhibition of an immune response.


ovulation from ovarian follicle

description: The process leading to the rupture of the follicle, releasing the centrally located oocyte into the oviduct. An example of this is found in Mus musculus.


formate oxidation

description: The chemical reactions and pathways by which formate is converted to CO2.


name: peptidyl-S-12-hydroxyfarnesyl-L-cysteine biosynthetic process from peptidyl-cysteine

description: The modification of peptidyl-cysteine to form S-12-hydroxyfarnesyl-L-cysteine; formation of S-farnesycysteine may be coupled with subsequent cleavage of a carboxy-terminal tripeptide for the CXXX motif and methyl esterification of the farnesylated cysteine.


epoxide metabolic process

description: The chemical reactions and pathways involving epoxides, compounds in which an oxygen atom is directly attached to two adjacent or non-adjacent carbon atoms of a carbon chain or ring system; thus cyclic ethers.


mast cell differentiation

description: The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a mast cell. A mast cell is a cell that is found in almost all tissues containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation.


response to tacrolimus

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tacrolimus stimulus.


description: Catalysis of the reaction: 2-(carboxymethyl)-5-oxo-2,5-dihydro-2-furoate = 3-carboxy-cis,cis-muconate + H+.


name: microtubule cytoskeleton attachment to nuclear envelope

description: A process in which the microtubule cytoskeleton is attached to the nuclear envelope.


butyrate catabolic process

description: The chemical reactions and pathways resulting in the breakdown of butyrate, the anion of butyric acid.


name: positive regulation of eosinophil activation

description: Any process that activates or increases the frequency, rate or extent of eosinophil activation.


orthokinesis

description: The movement of a cell or organism in response to a stimulus in which the speed or frequency of movement is increased or decreased.


description: Catalysis of the reaction: 2-cis,6-cis-farnesyl diphosphate = (-)-endo-alpha-bergamotene + diphosphoric acid.


name: chromium ion transmembrane transporter activity

description: Enables the transfer of chromium (Cr) ions from one side of a membrane to the other.


nicotianamine catabolic process

description: The chemical reactions and pathways resulting in the breakdown of nicotianamine, 2(S),3'2(S),3''(S)-N-(N-(3-amino-3-carboxypropyl)-3-amino-3-carboxypropyl)-azetidine-2-carboxylic acid.


malonyl-CoA metabolic process

description: The chemical reactions and pathways involving malonyl-CoA, the S-malonyl derivative of coenzyme A.


lipopolysaccharide transfer activity

description: Removes a lipopolysaccharide (LPS) from the outer leaflet of a donor membrane, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to the outer leaflet of an acceptor membrane.


synoviocyte proliferation

description: The multiplication or reproduction of type B synoviocytes by cell division, resulting in the expansion of their population. A type B synoviocyte is a fibroblast-like cell found in synovial tissues.


name: negative regulation of neutrophil mediated cytotoxicity

description: Any process that decreases the frequency, rate or extent of the directed killing of a target cell by a neutrophil.


hepoxilin metabolic process

description: The chemical reactions and pathways involving hepoxilins, a class of bioactive icosanoids with roles in the regulation of cell physiology.


name: negative regulation of multicellular organism growth

description: Any process that stops, prevents, or reduces the frequency, rate or extent of growth of an organism to reach its usual body size.


quercetin O-glucoside metabolic process

description: The chemical reactions and pathways involving O-glucosylated derivatives of quercetin.


cellular response to methionine

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methionine stimulus.


description: Catalysis of the reaction: 5-hydroxypyrrole-2-carboxylate = 5-oxo-4,5-dihydropyrrole-2-carboxylate.


regulation of fibroblast migration

description: Any process that modulates the rate, frequency or extent of fibroblast cell migration. Fibroblast cell migration is accomplished by extension and retraction of a pseudopodium.


premature acrosome loss

description: The discharge, by sperm, of a single, anterior secretory granule before the sperm reaches to the zona pellucida of the oocyte. The process begins with the fusion of the outer acrosomal membrane with the sperm plasma membrane and ends with the exocytosis of the acrosomal contents.


name: protein localization to perinuclear region of cytoplasm

description: A process in which a protein is transported to, or maintained in, a location within the perinuclear region of the cytoplasm.


description: Catalysis of the reaction: 5,10-methenyltetrahydrofolate + H2O = 10-formyltetrahydrofolate.


name: fucose transmembrane transporter activity

description: Enables the transfer of fucose from one side of a membrane to the other. Fucose is 6-deoxygalactose and has two enantiomers, D-fucose and L-fucose.


MutLbeta complex binding

description: Binding to a MutLbeta mismatch repair complex.


neuron cell-cell adhesion

description: The attachment of a neuron to another cell via adhesion molecules.


name: negative regulation of hexasaccharide transport

description: Any process that stops, prevents or reduces the frequency, rate or extent of hexasaccharide transport.


embryonic lung development

description: The process occurring during the embryonic phase whose specific outcome is the progression of the lung over time, from its formation to the mature structure.


forebrain neuroblast division

description: The division of a neuroblast located in the forebrain. Neuroblast division gives rise to at least another neuroblast.


taurine catabolic process

description: The chemical reactions and pathways resulting in the breakdown of taurine (2-aminoethanesulfonic acid), a sulphur-containing amino acid derivative important in the metabolism of fats.


Ras palmitoyltransferase activity

description: Catalysis of the reaction: palmitoyl-CoA + protein-cysteine = S-palmitoyl protein + CoA, specific for Ras proteins.


name: abscisic acid-activated signaling pathway involved in stomatal movement

description: Any abscisic acid mediated signaling pathway that is involved in stomatal movement.


detection of gibberellic acid stimulus

description: The series of events in which a gibberellic acid stimulus is received by a cell and converted into a molecular signal.


name: rhamnogalacturonan alpha-L-rhamnopyranosyl-(1->4)-alpha-D-galactopyranosyluronide lyase activity

description: Catalysis of the cleavage of rhamnogalacturonan, generating oligosaccharides of the form alpha-D-us-galacturonic acid-(1,2)-alpha-L-rhamnose-(1,4)-alpha-D-galacturonate-(1,2)-L-rhamnose-(1,2)-alpha-L-rhamnose-p-(1,4)-alpha-D-galacturonic acid, terminating at the non-reducing end with a hex-4-enopyranosyluronic acid residue.


name: epithelial-mesenchymal cell signaling involved in lung development

description: Any process that results in the transfer of information from an epithelial cell to a mesenchymal cell and contributes to the progression of the lung over time from its initial formation to the mature organ.


name: lysophosphatidic acid acyltransferase activity

description: Catalysis of the transfer of acyl groups from an acyl-CoA to lysophosphatidic acid to form phosphatidic acid.


floral organ development

description: The process whose specific outcome is the progression of the floral organ over time, from its formation to the mature structure.


GTP metabolic process

description: The chemical reactions and pathways involving GTP, guanosine triphosphate.


name: regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation

description: Any process that modulates the frequency, rate or extent of CD8-positive, alpha-beta cytotoxic T cell extravasation.


acylglycerol homeostasis

description: Any process involved in the maintenance of an internal steady state of acylglycerol within an organism or cell.


description: Catalysis of the reaction: 2,3-dihydroxybenzoate + ATP + holo-[ACP] = 2,3-dihydroxybenzoyl-[ACP] + AMP + diphosphate.


description: Catalysis of the addition of mannose to dolichyl-pyrophosphate Man7GlcNAc2 (also written as Man7GlcNAc2-PP-Dol) in alpha-(1->6) linkage, producing Man8GlcNAc2-PP-Dol.


urethra development

description: The progression of the urethra over time from its initial formation to the mature structure. The urethra is a renal system organ that carries urine from the bladder to outside the body.


cellular response to estradiol stimulus

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by estradiol, a C18 steroid hormone hydroxylated at C3 and C17 that acts as a potent estrogen.


cellular response to UV-C

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-C radiation stimulus. UV-C radiation (UV-C light) spans the wavelengths 100 to 280 nm.


rifamycin-B oxidase activity

description: Catalysis of the reaction: 2 H+ + O2 + rifamycin B = H2O2 + rifamycin O.


name: regulation of adult chitin-containing cuticle pigmentation

description: Any process that modulates the frequency, rate or extent of establishment of the adult pattern of pigmentation in the cuticle of an organism.


name: cell fate specification involved in pattern specification

description: The process involved in the specification of the identity of a cell in a field of cells that is being instructed as to how to differentiate. Once specification has taken place, that cell will be committed to differentiate down a specific pathway if left in its normal environment.


nitrile hydratase activity

description: Catalysis of the reaction: an aliphatic amide = a nitrile + H2O.


riboflavin kinase activity

description: Catalysis of the reaction: ATP + riboflavin = ADP + FMN + 2 H+.


polysaccharide binding

description: Binding to a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically.


name: pre-mRNA intronic pyrimidine-rich binding

description: Binding to a pyrimidine-rich (CU-rich) intronic sequence of a pre-messenger RNA (pre-mRNA).


cellular response to ethylene stimulus

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ethylene (ethene) stimulus.


exo-(1,4)-alpha-D-glucan lyase activity

description: Catalysis of the reaction: linear alpha-D-glucan = 1,5-anhydro-D-fructose + beta-D-glucose.


pollen tube development

description: The process whose specific outcome is the progression of a pollen tube over time, from its initial formation to a mature structure.


metanephric nephron tubule formation

description: The developmental process pertaining to the initial formation of a metanephric nephron tubule from unspecified parts. A metanephric nephron tubule is an epithelial tube that is part of a nephron in the metanephros.


glycolipid floppase activity

description: Catalysis of the movement of a glycolipid from the cytosolic to the exoplasmic leaftlet of a membrane, using energy from the hydrolysis of ATP.


name: positive regulation of cell adhesion involved in single-species biofilm formation

description: Any process that activates or increases the frequency, rate or extent of cell adhesion involved in single-species biofilm formation.


name: methylglyoxal reductase (NADPH) (acetol producing) activity

description: Catalysis of the reaction: hydroxyacetone + NADP+ = H+ + methylglyoxal + NADPH.


description: Catalysis of the reaction: H2O + N-(long-chain-acyl)ethanolamine = ethanolamine + a fatty acid.


regulation of sporangiospore formation

description: Any process that modulates the frequency, rate or extent of sporangiospore formation, a process in which sporangiospores, a type of asexual spore found in fungi, are formed. Sporangiospores are formed within sac-like structure, the sporangium, following the division of the cytoplasm.


name: positive regulation of smooth muscle hypertrophy

description: Any process that activates or increases the frequency, rate or extent of smooth muscle hypertrophy.


RNA polymerase III assembly

description: The aggregation, arrangement and bonding together of a set of components to form the eukaryotic RNA polymerase III complex.


description: Catalysis of the reaction: (2S,3S)-2,3-dihydroxy-2,3-dihydrobenzoate + NAD+ = 2,3-dihydroxybenzoate + H+ + NADH.


cellular response to purvalanol A

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a purvalanol A stimulus.


name: hydroxymethyl-, formyl- and related transferase activity

description: Catalysis of the transfer of a hydroxymethyl- or formyl group from one compound (donor) to another (acceptor).


chloroplast mRNA modification

description: The covalent alteration within the chloroplast of one or more nucleotides within an mRNA to produce an mRNA molecule with a sequence that differs from that coded genetically.


tongue muscle cell differentiation

description: The process in which a relatively unspecialized cell acquires specialized features of a tongue muscle cell.


proximal/distal pattern formation

description: The regionalization process in which specific areas of cell differentiation are determined along a proximal/distal axis. The proximal/distal axis is defined by a line that runs from main body (proximal end) of an organism outward (distal end).


vesicle tethering

description: The initial, indirect interaction between a vesicle membrane and a membrane to which it is targeted for fusion. This interaction is mediated by tethering factors (or complexes), which interact with both membranes. Interaction can occur via direct binding to membrane phospholipids or membrane proteins, or via binding to vesicle coat proteins. This process is distinct from and prior to interaction between factors involved in fusion.


subsynaptic reticulum organization

description: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a subsynaptic reticulum. A subsynaptic reticulum is an elaborate tubulolamellar membrane system that underlies the postsynaptic cell membrane.


description: Catalysis of the reaction: N-(6-aminohexanoyl)-6-aminohexanoate + H2O = 2 6-aminohexanoate.


detection of endogenous stimulus

description: The series of events in which an endogenous stimulus is received by a cell and converted into a molecular signal.


name: protein localization to bicellular tight junction

description: A process in which a protein is transported to, or maintained in, a location within a bicellular tight junction.


(R)-lactaldehyde dehydrogenase activity

description: Catalysis of the reaction: (R)-propane-1,2-diol + NADP = (R)-lactaldehyde + NADPH + H+.


skeletal muscle adaptation

description: Any process in which skeletal muscles change their phenotypic profiles in response to altered functional demands and a variety of signals.


name: negative regulation of fibroblast chemotaxis

description: Any process that stops, prevents or reduces the frequency, rate or extent of fibroblast chemotaxis.


name: positive regulation of spermidine biosynthetic process

description: Any process that activates or increases the frequency, rate or extent of spermidine biosynthetic process.


description: Catalysis of the reaction: luteolin 7-O-beta-D-glucosiduronate + UDP-alpha-D-glucuronate = H+ + luteolin 7-O-[(beta-D-glucosiduronate)-(1->2)-(beta-D-glucosiduronate)] + UDP.


name: positive regulation of dopamine metabolic process

description: Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving dopamine.


anaerobic amino acid catabolic process

description: The anaerobic chemical reactions and pathways resulting in the breakdown of amino acids, yielding energy in the form of ATP.


name: positive regulation of imaginal disc-derived leg joint morphogenesis

description: Any process that activates or increases the frequency, rate or extent of imaginal disc-derived leg joint morphogenesis.


name: positive regulation of cell adhesion involved in sprouting angiogenesis

description: Any process that activates or increases the frequency, rate or extent of cell adhesion involved in sprouting angiogenesis.


name: positive regulation of cell proliferation involved in mesonephros development

description: Any process that activates or increases the frequency, rate or extent of cell proliferation involved in mesonephros development.


name: (gibberellin-36), 2-oxoglutarate:oxygen oxidoreductase activity

description: Catalysis of the reaction: gibberellin A36 + O2 + 2-oxoglutarate = H+ + gibberellin A4 + succinate + 2 carbon dioxide.


inositol catabolic process

description: The chemical reactions and pathways resulting in the breakdown of inositol, 1,2,3,4,5,6-cyclohexanehexol, a growth factor for animals and microorganisms.


name: 3,3'-dibromobisphenol A reductive dehalogenase activity

description: Catalysis of the reaction: 3,3'-dibromobisphenol A + 2 H+ + 2 e- = 3-monobromobisphenol A + HBr.


name: negative regulation of melanocyte differentiation

description: Any process that stops, prevents, or reduces the frequency, rate or extent of melanocyte differentiation.


positive regulation of heart rate

description: Any process that activates or increases the frequency or rate of heart contraction.


name: positive regulation of galactoglucomannan catabolic process

description: Any process that activates or increases the frequency, rate or extent of galactoglucomannan catabolic process.


cellular response to chitin

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chitin stimulus.


name: regulation of myofibroblast cell apoptotic process

description: Any process that modulates the frequency, rate or extent of myofibroblast cell apoptotic process.


cellular response to genistein

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a genistein stimulus.


name: positive regulation of netrin-activated signaling pathway

description: Any process that activates or increases the frequency, rate or extent of netrin-activated signaling pathway.


name: 23S rRNA (adenine(1618)-N(6))-methyltransferase activity

description: Catalysis of the reaction: S-adenosyl-L-methionine + adenine(1618) in 23S rRNA = S-adenosyl-L-homocysteine + rRNA containing N(6)-methyladenine(1618) in 23S rRNA.


formaldehyde catabolic process

description: The chemical reactions and pathways resulting in the breakdown of formaldehyde (methanal, H2C=O), the simplest aldehyde.


cellulose synthase activity

description: Catalysis of the reaction: nucleoside-disphosphate-glucose + ((1,4)-beta-D-glucosyl)(n) = nucleoside-disphosphate + ((1,4)-beta-D-glucosyl)(n+1).


CCG codon-amino acid adaptor activity

description: A triplet codon-amino acid adaptor activity that recognizes a CCG codon.


name: protein localization to horsetail-astral microtubule array

description: A process in which a protein is transported to, or maintained in, a location within a horsetail-astral microtubule array.


vitellogenin receptor activity

description: Receiving vitellogenin, and delivering vitellogenin into the cell via endocytosis.


description: Catalysis of the hydrolysis of glucosidic link in beta-gentiobiose.


description: Catalysis of the reaction: (S)-3-(imidazol-5-yl)lactate + NADP+ = 3-(imidazol-5-yl)pyruvate + NADPH + H+.


acetoacetate decarboxylase activity

description: Catalysis of the reaction: acetoacetate + H+ = acetone + CO2.


name: L-asparagine:sodium symporter activity

description: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: L-asparagine(out) + Na+(out) = L-asparagine(in) + Na+(in).


strictosidine beta-glucosidase activity

description: Catalysis of the reaction: 3alpha(S)-strictosidine + H2O = D-glucose + strictosidine aglycone.