name: 4-{[((R)-1-Hydroxycarbamoyl-2-thiophen-2-yl-ethyl)-(4-methoxy-benzenesulfonyl)-amino]-methyl}-benzoic acid methyl ester


name: [(1R,2R)-1-((R)-1-Hydroxycarbamoyl-2-thiazol-4-yl-ethylcarbamoyl)-2-methyl-butyl]-carbamic acid benzyl ester


name: {(1R,2R)-1-[2-(4-tert-Butoxy-phenyl)-1-hydroxycarbamoyl-ethylcarbamoyl]-2-methyl-butyl}-carbamic acid benzyl ester


name: (R)-2-{3-[(R)-4-Hydroxycarbamoyl-4-(4-methoxy-benzenesulfonylamino)-butyl]-ureido}-3-phenyl-propionic acid methyl ester


name: {(1R,2R)-1-[2-(2-Chloro-phenyl)-1-hydroxycarbamoyl-ethylcarbamoyl]-2-methyl-butyl}-carbamic acid benzyl ester


name: [(1R,2R)-1-(2-Biphenyl-4-yl-1-hydroxycarbamoyl-ethylcarbamoyl)-2-methyl-butyl]-carbamic acid benzyl ester


name: {(1R,2R)-1-[(R)-1-Hydroxycarbamoyl-2-(4-nitro-phenyl)-ethylcarbamoyl]-2-methyl-butyl}-carbamic acid benzyl ester


name: {(1R,2R)-1-[(R)-2-(4-Bromo-phenyl)-1-hydroxycarbamoyl-ethylcarbamoyl]-2-methyl-butyl}-carbamic acid benzyl ester


name: 4-{[((R)-1-Carboxy-2-thiophen-2-yl-ethyl)-(4-methoxy-benzenesulfonyl)-amino]-methyl}-benzoic acid methyl ester


name: {(1R,2R)-1-[(R)-2-(5-Bromo-thiophen-2-yl)-1-hydroxycarbamoyl-ethylcarbamoyl]-2-methyl-butyl}-carbamic acid benzyl ester


name: [(1R,2R)-1-((R)-1-Hydroxycarbamoyl-2-pyridin-2-yl-ethylcarbamoyl)-2-methyl-butyl]-carbamic acid benzyl ester


name: {(1R,2R)-1-[(R)-1-Hydroxycarbamoyl-2-(1H-imidazol-4-yl)-ethylcarbamoyl]-2-methyl-butyl}-carbamic acid benzyl ester


name: (R)-4-[Benzo[1,3]dioxol-5-ylmethyl-(4-methoxy-benzenesulfonyl)-amino]-4-hydroxycarbamoyl-butyric acid methyl ester


name: (R)-2-[Benzo[1,3]dioxol-5-ylmethyl-(4-methoxy-benzenesulfonyl)-amino]-pentanedioic acid 5-cyclohexyl ester


name: {(1R,2S)-1-[(R)-1-Hydroxycarbamoyl-2-(1H-indol-3-yl)-ethylcarbamoyl]-2-methyl-butyl}-carbamic acid benzyl ester


name: {1-[(R)-1-Hydroxycarbamoyl-2-(1H-indol-3-yl)-ethylcarbamoyl]-butyl}-carbamic acid benzyl ester


Vitamin E

An alpha-tocopherol that has R,R,R configuration. The naturally occurring stereoisomer of alpha-tocopherol, it is found particularly in sunflower and olive oils.


name: 9H-Xanthene-4-propanoic acid, 7-carboxy-3-((6-(4-methoxyphenyl)-5-hexenyl)oxy)-9-oxo-, (E)-


name: 7-[3-(4-Acetyl-2-ethyl-5-hydroxyphenoxy)propoxy]-3,4-dihydro-8-propyl-2h-1-benzopyran-2-carboxylic acid sodium salt


name: 6-(4,6-Diphenyl-pyridin-2-yloxy)-hexanoic acid methyl ester


name: 2-(4,5-Dihydro-1H-imidazol-2-yl)-4-methyl-3,4-dihydro-2H-benzo[1,4]oxazine-6-carboxylic acid methyl ester


ANDROSTANDIOL

The 5alpha-stereoisomer of androstane-3alpha,17beta-diol.


A 17beta-hydroxy steroid, being 17beta-estradiol methoxylated at C-2.


A 3-hydroxy steroid that is obtained by formal dehydrogenation across positions 6 and 7 of 17beta-estradiol.


A 3-hydroxy steroid that is obtained by formal dehydrogenation across positions 7 and 8 of 17beta-estradiol.


EQUILENIN

A 3-hydroxy steroid that is estrone which carries two double bonds at positions 6 and 8. It is found in the urine of pregnant mare's and extensively used for estrogen replacement therapy in postmenopausal women.


A 3-hydroxy steroid resulting from deoxygenation at position 17 of estradiol or estrone.


A C19-steroid that is testosterone in which the hydrogen at the 16alpha position has been replaced by a hydroxy group.


dehydroepiandrosterone

An androstanoid that is androst-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 17. It is a naturally occurring steroid hormone produced by the adrenal glands.


ANDROSTERONE

An androstanoid that is 5alpha-androstane having a hydroxy substituent at the 3alpha-position and an oxo group at the 17-position. It is a metabolite of dehydroepiandrosterone .


pregnenolone

A 20-oxo steroid that is pregn-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 20.


MATAIRESINOL

A lignan that is gamma-butyrolactone in which the 3 and 4 positions are substituted by 4-hydroxy-3-methoxybenzyl groups (the 3R,4R-diastereomer).


A hydroxypregnenolone carrying an alpha-hydroxy group at position 17.


ETIOCHOLANOLONE

An androstanoid that is 5beta-androstane substituted by an alpha-hydroxy group at position 3 and an oxo group at position 17. It is a metabolite of testosterone in mammals.


PURPUROGALLIN

A cyclic ketone that is 5H-benzocycloheptene bearing an oxo group at position 5 and hydroxy groups at positions 2, 3, 4 and 6.


γ-linolenic acid

A C18, omega-6 acid fatty acid comprising a linolenic acid having cis- double bonds at positions 6, 9 and 12.


MENTHOL

Any secondary alcohol that is one of the eight possible diastereoisomers of 5-methyl-2-(propan-2-yl)cyclohexan-1-ol.


name: 4-(4-Biphenyl)butyldiphosphonic Acid Tetrapotassium Salt


name: 1-Phosphono-4-[3-(2-benzylphenoxy)phenyl]butylsulfonic Acid Tripotassium Salt


name: 1-Phosphono-4-[3-(4-fluorophenoxy)-6-fluoro-phenyl]butylsulfonic Acid Tripotassium Salt


name: 1-Phosphono-4-[3-(2-fluorophenoxy)phenyl]butylsulfonic Acid Tripotassium Salt


name: 1-Phosphono-4-[3-(3-fluorophenoxy)phenyl]butylsulfonic Acid Tripotassium Salt


name: 1-Phosphono-4-[3-(4-fluorophenoxy)phenyl]butylsulfonic Acid Tripotassium Salt


name: 1-Phosphono-4-[3-(4-chlorophenoxy)phenyl]butylsulfonic Acid Tripotassium Salt


name: (+/-)-1-Phosphono-4-(3-phenoxyphenyl)butylsulfonic Acid Tripotassium Salt


name: 1-Phosphono-4-[3-(3,5-difluorophenoxy)phenyl]butylsulfonic Acid Tripotassium Salt


name: 1-Phosphono-4-[3-(3,4-difluorophenoxy)phenyl]butylsulfonic Acid Tripotassium Salt


name: 1-Phosphono-4-(4-phenoxyphenyl)butylsulfonic Acid Tripotassium Salt


name: 1-Phosphono-4-[3-(3-trifluoromethylphenoxy)phenyl]butylsulfonic Acid Tripotassium Salt


name: 1-Phosphono-4-(3-benzylphenyl)butylsulfonic Acid Tripotassium Salt


name: 4-(4-Biphenyl)butyldiphosphonic Acid tripotassium salt


name: 1-Phosphono-4-(3-phenylaminophenyl)butylsulfonic Acid Tripotassium Salt


name: 1-Phosphono-4-[4-(4-butylphenyl)phenyl]butylsulfonic Acid Tripotassium Salt


name: 1-Phosphono-4-[3-(4-trifluoromethylphenoxy)phenyl]butylsulfonic Acid Tripotassium Salt


name: 1-Phosphono-4-[4-(2,4-difluorophenyl)phenyl]butylsulfonic Acid Tripotassium Salt


name: 1-Phosphono-4-[4-(4-methylphenyl)phenyl]butylsulfonic Acid Tripotassium Salt


B 581

A dipeptide obtained from the tetrapeptide Cys-Val-Phe-Met by reduction of the amide carbonyl groups of the Cys and Val residues.


name: 1-Phosphono-4-(4-biphenyl)butylsulfonic Acid Tripotassium Salt


name: 1-Phosphono-3-(3-phenoxyphenyl)propylsulfonic Acid Tripotassium Salt


name: 1-Phosphono-4-[3-(4-benzylphenoxy)phenyl]butylsulfonic Acid Tripotassium Salt


DIPHENYLENEIODONIUM

An organic cation that is fluorene in which the methylene group is replaced by a positively charged iodine.


khellin

A furanochrome in which the basic tricyclic skeleton is substituted at positions 4 and 9 with methoxy groups and at position 7 with a methyl group. A major constituent of the plant Ammi visnaga it is a herbal folk medicine used for various illnesses, its main effect being as a vasodilator.


clioquinol

A monohydroxyquinoline that is quinolin-8-ol in which the hydrogens at positions 5 and 7 are replaced by chlorine and iodine, respectively. It has antibacterial and atifungal properties, and is used in creams for the treatment of skin infections. It has also been investigated as a chelator of copper and zinc ions for the possible treatment of Alzheimer's disease.


name: 5-hydroxy-2-methyl-3-benzo[g]benzofurancarboxylic acid ethyl ester


name: 6,11-dioxo-12-naphtho[2,3-b]indolizinecarboxylic acid ethyl ester


BENZO[E]PYRENE

An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings. It is listed as a Group 3 carcinogen by the IARC.


thiabendazole

A member of the class of benzimidazoles carrying a 1,3-thiazol-4-yl substituent at position 2. A mainly post-harvest fungicide used to control a wide range of diseases including Aspergillus, Botrytis, Cladosporium and Fusarium.


hycanthone

A thioxanthen-9-one compound having a hydroxymethyl substituent at the 1-position and a 2-[(diethylamino)ethyl]amino substituent at the 4-position. It was formerly used (particularly as the monomethanesulfonic acid salt) as a schistosomicide for individual or mass treatement of infection with Schistosoma haematobium and S. mansoni, but due to its toxicity and concern about possible carcinogenicity, it has been replaced by other drugs such as praziquantel.


name: Carbamimidothioic acid, (4-oxo-2-phenyl-4H-1-benzopyran-8-yl)methyl ester, monohydrobromide


name: 2-[[(4-fluorophenyl)-oxomethyl]amino]benzoic acid methyl ester


CIS-RESVERATROL

The cis-stereoisomer of  resveratrol.


9-anthroic acid

An anthroic acid carrying the carboxy substituent at position 9.


sulmazole

An imidazopyridine that is 1H-imidazo[4,5-b]pyridine which is substituted at position 2 by a 2-methoxy-4-(methylsulfinyl)phenyl group. An A1 adenosine receptor antagonist, it was formerly used as a cardiotonic agent.


name: 3-[5-[oxo-(3-pyridinylamino)methyl]-2-furanyl]-2-thiophenecarboxylic acid methyl ester


butamben

An amino acid ester resulting from the formal condensation of the carboxy group of 4-aminobenzoic acid with the hydroxy group of butan-1-ol. Its local anaesthetic properties have been used for surface anaesthesia of the skin and mucous membranes, and for relief of pain and itching associated with some anorectal disorders.


ICI 118551

An indane substituted at position 7 by a methyl group and at position 4 by a 3-(isopropylamino)-2-hydroxybutoxy group (the 2R,3S-diastereomer).


albendazole

A carbamate ester that is methyl 1H-benzimidazol-2-ylcarbamate substituted by a propylsulfanyl group at position 5. It is commonly used in the treatment of parasitic worm infestations.


name: Acetic acid, 2-[(6-methoxy-4-methyl-2-quinolinyl)thio]-, hydrazide


name: 6-amino-4-(5-chloro-2-thiophenyl)-5-cyano-2-phenyl-4H-pyran-3-carboxylic acid ethyl ester


FUROXAN

A 1,2,5-oxadiazole substituted by an oxido, cyano and phenyl groups at positions 2, 3 and 4, respectively. It is a vasodilator and inhibitor of platelet aggregation.


name: (4-Oxo-2-phenyl-4H-quinazolin-3-yl)-acetic acid ethyl ester


name: N-[6-(propan-2-ylthio)-1H-benzimidazol-2-yl]carbamic acid methyl ester


name: 4-(4-Fluoro-phenyl)-1-isobutyl-1,4-dihydro-pyrrolo[3,2-b]pyrrole-2-carboxylic acid methyl ester


(S)-profenamine

The (S)-enantiomer of profenamine.


name: (2-Phenyl-quinazolin-4-ylsulfanyl)-acetic acid ethyl ester


name: (8-Fluoro-5H-[1,2,4]triazino[5,6-b]indol-3-ylsulfanyl)-acetic acid benzyl ester


MPEP

A methylpyridine that coinsists of 2-methylp[yridine bearing an additional phenylethynyl group at position 6. Potent and highly selective non-competitive antagonist at the mGlu5 receptor subtype (IC50 = 36 nM) and a positive allosteric modulator at mGlu4 receptors. Centrally active following systemic administration in vivo. Reverses mechanical hyperalgesia in the inflamed rat hind paw.


name: 4-phenoxy-2-phenyl-5-pyrimidinecarboxylic acid ethyl ester


HARMAN

An indole alkaloid fundamental parent with a structure of 9H-beta-carboline carrying a methyl substituent at C-1. It has been isolated from the bark of Sickingia rubra, Symplocus racemosa, Passiflora incarnata, Peganum harmala, Banisteriopsis caapi and Tribulus terrestris, as well as from tobacco smoke. It is a specific, reversible inhibitor of monoamine oxidase A.


name: 6-Methoxy-3-[(4-methyl-furazan-3-carbonyl)-amino]-1H-indole-2-carboxylic acid methyl ester


NOCODAZOLE

A member of the class of benzimidazoles that is benzimidalole which is substituted at position 2 by a (methoxycarbonyl)amino group and at position 5 by a 2-thienoyl group. It is an antineoplastic agent that exerts its effect by depolymerising microtubules.


fenbendazole

A member of the class of benzimidazoles that is 1H-benzimidazole  which is substituted at positons 2 and 5 by (methoxycarbonyl)amino and phenylsulfanediyl groups, respectively. A broad-spectrum anthelmintic, it is used, particularly in veterinary medicine, for the treatment of nematodal infections.


name: 3-(5-Mercapto-tetrazol-1-yl)-benzoic acid methyl ester


name: 2-(2,2-Dimethyl-propionylamino)-5,6-dihydro-4H-cyclopenta[b]thiophene-3,4-dicarboxylic acid dimethyl ester


DIFLUFENICAN

A pyridinecarboxamide that is pyridine-3-carboxamide substituted by a 2,4-difluorophenyl group at the carbamoyl nitrogen and a 3-(trifluoromethyl)phenoxy group at position 2.


name: (4,6-Dimethyl-pyrimidin-2-ylsulfanyl)-acetic acid (6-methyl-benzothiazol-2-ylcarbamoyl)-methyl ester


name: 3-(4-Phenoxy-butyrylamino)-benzoic acid methyl ester


name: 2-[[2-furanyl(oxo)methyl]amino]-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxylic acid methyl ester


name: 4-(4-ethoxycarbonylanilino)-2-quinazolinecarboxylic acid ethyl ester


name: 4-(4-Fluoro-phenyl)-1-isopropyl-1,4-dihydro-pyrrolo[3,2-b]pyrrole-2-carboxylic acid methyl ester


name: (Z)-3-(3,4-Dihydroxyphenyl)propenoic acid 2-phenylethyl ester


fMet-Leu-Phe

A tripeptide composed of L-Met, L-Leu and L-Phe in a linear sequence with a formyl group at the amino terminus. It acts as a potent inducer of leucocyte chemotaxis and macrophage activator as well as a ligand for the FPR receptor.


name: 6-Chloro-2,3-dihydro-imidazo [2,1-b]thiazole-5-sulfonic Acid (1-H-indol-5-yl)-amide


name: 4-(1-Benzenesulfonyl-1H-indol-3-yl)-3,6-dihydro-2H-pyridine-1-carboxylic acid tert-butyl ester


name: (2-Ethyl-8-methoxy-1-oxo-3-thioxo-2,3-dihydro-1H-imidazo[1,5-a]indol-6-yloxy)-acetic acid tert-butyl ester


DEQUALINIUM CHLORIDE

An organic chloride salt that is the dichloride salt of dequalinium.


name: 5,5-Dimethyl-2-(4-morpholin-4-yl-4-oxo-butyrylamino)-4,7-dihydro-5H-thieno[2,3-c]pyran-3-carboxylic acid ethyl ester


name: [6-Fluoro-2-(4-fluoro-phenyl)-quinazolin-4-ylsulfanyl]-acetic acid isopropyl ester


sulfaphenazole

A sulfonamide that is sulfanilamide in which the sulfonamide nitrogen is substituted by a 1-phenyl-1H-pyrazol-5-yl group. It is a selective inhibitor of cytochrome P450 (CYP) 2C9 isozyme, and antibacterial agent.


noscapine

A benzylisoquinoline alkaloid that is 1,2,3,4-tetrahydroisoquinoline which is substituted by a 4,5-dimethoxy-3-oxo-1,3-dihydro-2-benzofuran-1-yl group at position 1, a methylenedioxy group at positions 6-7 and a methoxy group at position 8. Obtained from plants of the Papaveraceae family, it lacks significant painkilling properties and is primarily used for its antitussive (cough-suppressing) effects.


name: {2-[(Thiophene-2-carbonyl)-amino]-acetylamino}-acetic acid 4-chloro-benzyl ester


name: ({[2-(Diethoxy-phosphorylamino)-ethyl]-ethyl-amino}-methyl)-phosphonic acid diethyl ester


name: 4-{2-[3-Pyridin-4-yl-5-(thiazol-2-ylcarbamoylmethylsulfanyl)-[1,2,4]triazol-1-yl]-acetylamino}-benzoic acid methyl ester


name: 5,5-Dimethyl-2-(4-morpholin-4-yl-butyrylamino)-4,7-dihydro-5H-thieno[2,3-c]pyran-3-carboxylic acid ethyl ester


name: Toluene-4-sulfonic acid 4-((E)-2-benzoylamino-2-phenylcarbamoyl-vinyl)-phenyl ester


name: 3,4,5-Trimethoxy-benzoic acid 2-[(4-methyl-benzoyl)-hydrazonomethyl]-phenyl ester


name: 2-[[2-methyl-5-(3-methyl-4-oxo-1-phthalazinyl)phenyl]sulfonylamino]acetic acid ethyl ester


name: (5-Morpholin-4-yl-1,2,3,4-tetrahydro-7-thia-6,9,11-triaza-benzo[c]fluoren-8-ylsulfanyl)-phenyl-acetic acid ethyl ester


name: 5-(Sec-butylamino-methyl)-furan-2-carboxylic acid methyl ester


name: {2-[(3-Amino-6-ethyl-thieno[2,3-b]quinoline-2-carbonyl)-amino]-thiazol-4-yl}-acetic acid ethyl ester


PLINABULIN

A member of the class of 2,5-diketopiperazines that is piperazine-2,5-dione substituted by benzylidene and (5-tert-butyl-1H-imidazol-4-yl)methylidene groups at positions 3 and 6, respectively. It is a vascular disrupting agent and a microtubule destabalising agent which was in clinical trials (now discontinued) for the treatment of non-small cell lung cancer.


(R)-acenocoumarol

The (R)-enantiomer of acenocoumarol.


(R)-betaxolol

The (R)-enantiomer of betaxolol.


name: 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 2-methoxyethyl 1-methylethyl ester, (4R)-


A member of the class of benzimidazoles that is 1,3-dihydro-2H-benzimidazol-2-one in which the hydrogens at positions 1 and 5 are replaced are replaced by 2-hydroxy-5-(trifluoromethyl)phenyl and trifluoromethyl groups, respectively. It is an opener/activator of the large-conductance calcium-activated potassium channel (Bkca).


name: Acetic acid 4,5-diacetoxy-2-(5-nitro-2,3-dihydro-indol-1-yl)-tetrahydro-pyran-3-yl ester


name: 2-Benzenesulfonylamino-4-methyl-thiazole-5-carboxylic acid ethyl ester


(S)-lorglumide sodium

An organic sodium salt obtained by formal condensation of N(2)-(3,4-dichlorobenzoyl)-N,N-dipentyl-L-alpha-glutamine with one equivalent of sodium hydroxide. The racemate is lorglumide sodium, a CCK antagonist.


name: 4-Chloro-2-methyl-3-(3-oxo-butyl)-quinoline-6-carboxylic acid ethyl ester


name: 2-[4-chloro-2-[3-(4-methoxyphenyl)-4-oxo-1,2-dihydroquinazolin-2-yl]phenoxy]acetic acid methyl ester


name: 4-{2-[4-(2-Amino-3-cyano-4H-benzo[h]chromen-4-yl)-2-methoxy-phenoxy]-acetylamino}-benzoic acid methyl ester


ZARDAVERINE

A pyridazinone derivative in which pyridazin-3(2H)-one is substituted at C-6 with a 4-(difluoromethoxy)-3-methoxyphenyl group.  It is a phosphodiesterase inhibitor, selective for PDE3 and 4.


name: Acetic acid (1R,3R)-2-acetoxy-1-hydroxycarbamoyl-3-phosphonooxy-propyl ester


4-phospho-D-erythronic acid

The D-enantiomer of 4-phosphoerythronic acid.


epicatechin gallate

A gallate ester obtained by formal condensation of the carboxy group of gallic acid with the (3R)-hydroxy group of epicatechin. A natural product found in Parapiptadenia rigida.


name: 4-[4-(2,4-Dioxothiazolidin-5-ylidenemethyl)-2-methoxyphenoxy]-3-trifluoromethylbenzoic Acid Methyl Ester


name: 4-[4-(2,4-Dioxothiazolidin-5-ylidenemethyl)-2-methoxyphenoxy]-3-chlorobenzoic Acid Methyl Ester


name: 4-[4-(2,4-Dioxothiazolidin-5-ylidenemethyl)-2-methoxyphenoxy]-2-trifluoromethylbenzoic Acid Methyl Ester


name: 2-[4-(2,4-Dioxothiazolidin-5-ylidenemethyl)-2-methoxyphenoxy]-5-trifluoromethylbenzoic Acid Methyl Ester


name: 4-[4-(2,4-Dioxothiazolidin-5-ylidenemethyl)-2-methoxyphenoxy]-3-bromobenzoic Acid Methyl Ester


name: Benzamide, 4-(((2E)-2-(aminomethyl)-3-fluoro-2-propen-1-yl)oxy)-N-(1,1-dimethylethyl)-, hydrochloride (1:1)


name: (S)-2-(2,4-Dimethyl-benzoylamino)-3-(4-nitro-phenyl)-propionic acid ethyl ester


name: (R)-2-[(S)-2-[(Naphthalene-1-carbonyl)-amino]-3-(4-nitro-phenyl)-propionylamino]-propionic acid ethyl ester


name: 3-[3-(3-Cyano-phenyl)-ureido]-2-[4-(4-fluoro-benzyl)-piperidin-1-ylmethyl]-benzoic acid methyl ester


name: (S)-2-[(Naphthalene-1-carbonyl)-amino]-3-(4-nitro-phenyl)-propionic acid ethyl ester


name: 3-[3-(3-Acetyl-phenyl)-ureido]-2-[4-(4-fluoro-benzyl)-piperidin-1-ylmethyl]-benzoic acid methyl ester


name: 2-[4-(4-Fluoro-benzyl)-piperidin-1-ylmethyl]-3-(3-phenyl-ureido)-benzoic acid methyl ester


name: 2-[4-(4-Fluoro-benzyl)-piperidin-1-ylmethyl]-3-[3-(3-methoxy-phenyl)-ureido]-benzoic acid methyl ester


name: (S)-2-[(Naphthalene-1-carbonyl)-amino]-3-(4-nitro-phenyl)-propionic acid benzyl ester


name: (R)-2-[(S)-2-[(Naphthalene-1-carbonyl)-amino]-3-(4-nitro-phenyl)-propionylamino]-propionic acid tert-butyl ester


name: (S)-2-[(Naphthalene-1-carbonyl)-amino]-3-(4-nitro-phenyl)-propionic acid isopropyl ester


name: 2-[4-(4-Fluoro-benzyl)-piperidin-1-ylmethyl]-4-(3-methoxy-phenylcarbamoyl)-piperazine-1-carboxylic acid tert-butyl ester


name: 4-[3-(3-Acetyl-phenyl)-ureido]-3-[4-(4-fluoro-benzyl)-piperidin-1-ylmethyl]-benzoic acid methyl ester


name: 2-{[1-(3,4-Dichloro-benzyl)-piperidin-4-ylcarbamoyl]-methylsulfanyl}-benzothiazole-6-carboxylic acid ethyl ester


name: (S)-2-[(Naphthalene-1-carbonyl)-amino]-3-(4-nitro-phenyl)-propionic acid tert-butyl ester


name: 3-[4-(4-Fluoro-benzyl)-piperidin-1-ylmethyl]-4-[3-(3-methoxy-phenyl)-ureido]-benzoic acid methyl ester


name: 4-[3-(3-Cyano-phenyl)-ureido]-3-[4-(4-fluoro-benzyl)-piperidin-1-ylmethyl]-benzoic acid methyl ester


name: (S)-3-(4-Hydroxy-phenyl)-2-[(naphthalene-1-carbonyl)-amino]-propionic acid ethyl ester


SCALARADIAL

A scalarane sesterterpenoid with formula C27H40O4. It is a natural product found in the marine sponges Spongia officinalis and Cacospongia mollior, and exhibits anti-inflammatory activity.


name: [[3-(2-amino-2-oxoethyl)-1-[(3-chlorophenyl)methyl]-2-methyl-1H-indol-4-yl]oxy]acetic acid sodium salt


name: [3-(1-Benzyl-3-carbamoylmethyl-2-ethyl-1H-indol-5-yloxy)-propyl]-phosphonic acid monomethyl ester


name: 2-[[3-(2-amino-1,2-dioxoethyl)-1-benzyl-2-ethyl-6,7,8,9-tetrahydro-1H-benz[g]indol-4-yl]oxy]acetic acid methyl ester


name: 2-[[3-(2-Amino-1,2-dioxoethyl)-2-methyl-1-benzyl-1,6,7,8-tetrahydrocyclopent[g]indol-4-yl]oxy]acetic acid methyl ester


name: 2-[[3-(2-Amino-1,2-dioxoethyl)-2-ethyl-1-benzyl-1,6,7,8-tetrahydrocyclopent[g]indol-4-yl]oxy]acetic acid methyl ester


name: 2-[[3-(2-amino-1,2-dioxoethyl)-1-benzyl-2-methyl-6,7,8,9-tetrahydro-1H-benz[g]indol-4-yl]oxy]acetic acid methyl ester


name: 2-[[3-(2-amino-1,2-dioxoethyl)-1-cyclohexylmethyl-2-methyl-1H-benz[g]indol-4-yl]oxy]acetic acid methyl ester


name: [3-(1-Benzyl-3-carbamoylmethyl-2-ethyl-1H-indol-5-yloxy)-propyl]-phosphonic acid dimethyl ester


name: 5-(1-Benzyl-3-carbamoylmethyl-2-methyl-1H-indol-6-yloxy)-pentanoic acid ethyl ester


name: 4-(1-Benzyl-3-carbamoylmethyl-2-methyl-1H-indol-6-yloxy)-butyric acid ethyl ester


name: Sodium salt of [3-(1-Benzyl-3-hydrazinocarbonyl-2-methyl-1H-indol-5-yloxy)-propyl]-phosphonic acid


name: (E)-3-[5,6-Bis-benzyloxy-3-(4-chloro-phenoxy)-benzo[b]thiophen-2-yl]-2-pyridin-4-yl-acrylic acid methyl ester


amodiaquine

A quinoline having a chloro group at the 7-position and an aryl amino group at the 4-position.


MARIZOMIB

A salinosporamide in which the core (1R)-6-oxa-2-azabicyclo[3.2.0]heptane-3,7-dione skeleton is substituted at positions 1, 4, and 5 by (1S)-cyclohex-2-en-1-yl(hydroxy)methyl, 2-chloroethyl, and methyl groups, respectively (the 1R,4R,5S diastereoisomer). A potent proteasome inhibitor, it has attracted interest for potential use in the treatment of various cancers.


coumarin

A chromenone having the keto group located at the 2-position.


VERATRIC ACID

A member of the class of benzoic acids that is benzoic acid substituted by methoxy groups at positions 2 and 3.


name: Adamantane-1-carboxylic acid (S)-1-pyridin-4-yl-ethyl ester


name: 2-Pyridin-4-yl-propionic acid (S)-2,6,6-trimethyl-bicyclo[3.1.1]hept-3-yl ester


name: 2-Pyridin-4-yl-butyric acid (S)-2,6,6-trimethyl-bicyclo[3.1.1]hept-3-yl ester


name: 2-Methyl-2-pyridin-4-yl-propionic acid (S)-2,6,6-trimethyl-bicyclo[3.1.1]hept-3-yl ester


name: 2-Methyl-2-pyridin-3-yl-propionic acid 2-methyl-adamantan-2-yl ester


name: 2-Methyl-2-pyridin-3-yl-propionic acid adamantan-1-yl ester


name: 2-Pyridin-3-yl-propionic acid (S)-2,6,6-trimethyl-bicyclo[3.1.1]hept-3-yl ester


name: 2-Methyl-2-pyridin-3-yl-propionic acid (S)-2,6,6-trimethyl-bicyclo[3.1.1]hept-3-yl ester


ORTERONEL

A member of the class of pyrroloimidazoles that is 6,7-dihydro-5H-pyrrolo[1,2-c]imidazole substituted by hydroxy and 6-(methylcarbamoyl)naphthalen-2-yl groups at position 7 (the 7S-stereoisomer). It is a non-steroidal 17,20-lyase inhibitor that suppresses androgen synthesis. It was previously in clinical development for the treatment of castration-resistant prostate cancer -- trial now discontinued.


name: 2-Pyridin-3-yl-propionic acid adamantan-1-yl ester


name: 2-Ethyl-2-pyridin-4-yl-butyric acid (S)-2,6,6-trimethyl-bicyclo[3.1.1]hept-3-yl ester


name: Pyridin-3-yl-acetic acid (3R,6R)-3,6,8,8-tetramethyl-octahydro-3a,7-methano-azulen-6-yl ester


name: Adamantane-1-carboxylic acid (R)-1-pyridin-4-yl-ethyl ester


name: Pyridin-3-yl-acetic acid (S)-2,6,6-trimethyl-bicyclo[3.1.1]hept-3-yl ester


name: Adamantane-1-carboxylic acid 1-methyl-1-pyridin-3-yl-ethyl ester


name: Pyridin-3-yl-acetic acid adamantan-1-yl ester


name: Adamantane-1-carboxylic acid (R)-1-pyridin-3-yl-ethyl ester


name: Adamantane-1-carboxylic acid (S)-1-pyridin-3-yl-ethyl ester


name: Pyridin-3-yl-acetic acid 2-methyl-adamantan-2-yl ester


An epoxy steroid that is pregnenolone which has an epoxy group whose oxygen is attached to the 16alpha and 17alpha-positions.


name: Adamantane-1-carboxylic acid pyridin-3-ylmethyl ester


tioconazole

A member of the class of imidazoles that comprises 2-(2,4-dichlorophenyl)ethylimidazole carrying an additional (2-chloro-3-thienyl)methoxy substituent at position 2.


ISOCONAZOLE

A member of the class of imidazoles that carries a 2-[(2,6-dichlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl group at position 1.


name: 2-Methyl-2-pyridin-3-yl-propionic acid (3R,6R)-3,6,8,8-tetramethyl-octahydro-3a,7-methano-azulen-6-yl ester


tasquinimod

Tasquinimod is a quinoline-3-carboxamide linomide analogue with antiangiogenic and potential antineoplastic activities. Tasquinimod has been shown to decrease blood vessel density but the exact mechanism of action is not known. This agent has also been shown to augment the antineoplastic effects of docetaxel and androgen ablation in a murine model of prostate cancer involving human prostate cancer xenografts.


name: (S)-1-Ethyl-6-methyl-4-phenyl-1,4-dihydro-pyridine-2,3,5-tricarboxylic acid 5-isopropyl ester


BAY 73-6691

A member of the class of pyrazolopyrimidines that is 4,5-dihydro-1H-pyrazolo[3,4-d]pyrimidine substituted by 2-chlorophenyl, oxo, and (2R)-3,3,3-trifluoro-2-methylpropyl groups at positions 1, 4 and 6, respectively. It is a potent and selective inhibitor of phosphodiesterase 9 (PDE9), currently in pre-clinical development for the treatment of Alzheimer's disease.


A phosphatidylcholine 24:0 in which the acyl groups at positions 1 and 2 are specified as lauroyl (dodecanoyl).


GABA

A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.


THIOCITRULLINE

An L-arginine derivative in which the guanidino NH2 group of L-arginine is replaced by a methylsufanyl group.


name: L-N omega-Nitroarginine-2,4-L-diaminobutyric amide (L-Arg NO2-L-Dbu-NH2.2TFA)


L-NAME

An alpha-amino acid ester that is the methyl ester of N(gamma)-nitro-L-arginine.


name: 4-(4-{6-[(Thiophene-2-carboximidoyl)-amino]-benzothiazol-2-ylamino}-piperidin-1-ylmethyl)-benzoic acid methyl ester


A 1,3-thiazole that is 4,5-dihydro-1,3-thiazole substituted by an amino group at position 2.


name: N(gamma)-nitro-L-arginine methyl ester hydrochloride

description: A hydrochloride obtained by combining N(gamma)-nitro-L-arginine methyl ester with one equivalent of hydrochloric acid.


tilarginine

A L-arginine derivative with a N(omega)-methyl substituent.


A macrolide that is the 7-oxo derivative of zeaenol (the 5Z stereoisomer). Isolated from Fungi, it exhibits cytotoxic, antibacterial and inhibitory activity against NF-kappaB.


A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 7-fluoro-3-[(2-fluoro-4-iodophenyl)amino]furo[3,2-c]pyridine-2-carboxylic acid with the amino group of (2S)-1-(aminooxy)propan-2-ol.


A carboxamide resulting from the formal condensation of the primary amino group of 4-propanoyl-1,3-thiazol-2-amine with the carboxy group of a 3-phenylbutiyric acid which has been substituted at position 2 by a (4R)-4-[p-(2-hydroxyethoxy)phenyl]-2,5-dioxoimidazolidin-1-yl group. It is a potent, highly selective inhibitormitogen-activated protein kinase 1/2 inhibitor.


FRAXINE

A beta-D-glucoside that is fraxetin attached to a beta-D-glucopyranosyl group at position 8 via a glycosidic linkage. It is a natural product isolated from the leaves of Fraxinus excelsior and exhibits potent hepatoprotective effects in vitro and in vivo.


A hydroxycoumarin that is coumarin in which the hydrogen at position 4 is replaced by a hydroxy group.


hymecromone

A hydroxycoumarin that is umbelliferone substituted by a methyl group at position 4.


FRAXETIN

A hydroxycoumarin that is 6-methoxycoumarin in which the hydrogens at positions 7 and 8 have been replaced by hydroxy groups.


gamma-valerolactone

A butan-4-olide that is dihydrofuran-2(3H)-one substituted by a methyl group at position 5. It has been found in the urine samples of humans exposed to n-hexane.


SCOPOLETIN

A hydroxycoumarin that is umbelliferone bearing a methoxy substituent at position 6.


name: 4-(2-Carboxy-6-hydroxy-benzoyl)-3,5-dihydroxy-benzoic acid (R)-3-(4-hydroxy-benzoylamino)-4-methyl-azepan-4-yl ester


name: [2-(1H-Indol-3-yl)-1-isobutylcarbamoyl-ethyl]-carbamic acid 1-trityl-1H-imidazol-4-ylmethyl ester


A member of the class of ureas that is 1-tert-butylurea in which one of the hydrogens attached to N(3) is substituted by a pyrido[2,3-d]pyrimidin-7-yl group, which is itself substituted at positions 2 and 6 by a 4-(diethylamino)butyl]amino group and a 3,5-dimethoxyphenyl group, respectively. It is a FGF/VEGF receptor tyrosine kinase inhibitor.


name: (R)-cyclic ((N-AC)Gla Leu Tyr Ach Asn Val Gly NPG Tyr Cys(O) NH2)


name: (R)-cyclic ((N-AC)Gla Leu Tyr Ach Asn Val Gly Cha Tyr Cys(O) NH2)


name: cyclic ((N-AC)Gla Leu Tyr Ach Asn Val Gly F5Phe Tyr Cys NH2)


name: cyclic ((N-AC)Gla Leu Tyr Ach Asn Val Gly NPG Tyr Cys NH2)


name: cyclic ((N-AC)Gla Leu Tyr Ach Asn Val Gly 2-Nal Tyr Cys NH2)


name: (R)-cyclic ((N-AC)Gla Leu Tyr Ach Asn Val Gly Nal Tyr Cys(O) NH2)


name: cyclic ((N-AC)Gla Leu Tyr Ach Asn Val Gly Bip Tyr Cys NH2)


name: cyclic ((N-AC)Gla Leu Tyr Ach Asn Val Gly Met Tyr Cys NH2)


name: cyclic ((N-AC)Gla Leu Tyr BCH Asn Val Gly Met Tyr Cys NH2)


name: cyclic ((N-AC)Gla Leu Tyr Ach Asn Val Gly Cha Tyr Cys NH2)


name: cyclic ((N-AC)Gla Leu Tyr Pro Asn Val Gly Met Tyr Cys NH2)


MANGOSTIN

A member of the class of xanthones that is 9H-xanthene substituted by hydroxy group at positions 1, 3 and 6, a methoxy group at position 7, an oxo group at position 9 and prenyl groups at positions 2 and 8. Isolated from the stems of Cratoxylum cochinchinense, it exhibits antioxidant, antimicrobial and antitumour activities.


An oxoicosatetraenoic acid having (5Z,8Z,11Z,13E) double bond stereochemistry, and an oxo group in position 15.


name: P-[[4-[(1-Oxodecyl)amino]phenyl]methyl]phosphonic Acid Cyclohexylamine Salt


1-myristoyl-sn-glycerol 3-phosphate

A 1-acyl-sn-glycerol 3-phosphate having myristoyl (tetradecanoyl) as the 1-O-acyl group.


Pontamine sky blue 5B (acid form)

A ring assembly consisting of two 5-amino-4-hydroxy-3-[(2-methoxyphenyl)diazenyl]naphthalene-2,7-disulfonic acid units joined by a 4,4'-linkage. The tetrasodium salt is the histological dye 'Pontamine sky blue 5B'.


name: 9Z-Octadecenoic acid, (2S)-3-[(hydroxymercaptophosphinyl)oxy]-2-methoxypropyl ester


name: octanoic acid (S)-2-octanoyloxy-3-thiophosphonooxy-propyl ester


name: alpha-Sulfone piperidine hydroxamate, 11c


name: alpha-Sulfone piperidine hydroxamate, 11e


name: alpha-Sulfone piperidine hydroxamate, 11m


name: alpha-Sulfone piperidine hydroxamate, 11b


name: alpha-Sulfone piperidine hydroxamate, 11d


name: alpha-Sulfone piperidine hydroxamate, 11f


name: alpha-Sulfone piperidine hydroxamate, 11h


name: (2R, 3R) 1-[4-(4-fluoro-2-methyl-benzyloxy)-benzenesulfonyl]-3-hydroxy-3-methyl-piperidine-2-carboxylic acid hydroxyamide


name: alpha-Sulfone piperidine hydroxamate, 11i


name: (2R,4R)-1-[4-(4-Fluoro-benzyloxy)-benzenesulfonyl]-2-hydroxycarbamoyl-piperidine-4-carboxylic acid methyl ester


name: 4-(4-But-2-ynyloxy-benzenesulfonyl)-3-hydroxycarbamoyl-piperazine-1-carboxylic acid methyl ester


name: alpha-Sulfone piperidine hydroxamate, 11k


name: alpha-Sulfone piperidine hydroxamate, 11n


name: alpha-Sulfone piperidine hydroxamate, 11j


name: (2S,3R)-3-Hydroxycarbamoyl-2-methyl-4-[4-(2-methyl-benzyloxy)-benzenesulfonyl]-piperazine-1-carboxylic acid methyl ester


name: (2S,3R)-3-Hydroxycarbamoyl-2-methyl-4-[4-(2-methyl-benzyloxy)-benzenesulfonyl]-piperazine-1-carboxylic acid ethyl ester


name: alpha-Sulfone piperidine hydroxamate, 11a


name: 4-(4-But-2-ynyloxy-benzenesulfonyl)-3-hydroxycarbamoyl-[1,4]diazepane-1-carboxylic acid tert-butyl ester


name: alpha-Sulfone piperidine hydroxamate, 1b


name: alpha-Sulfone piperidine hydroxamate, 11l


name: alpha-Sulfone piperidine hydroxamate, 1c


name: (2R,4R)-1-[4-(4-Fluoro-phenoxy)-benzenesulfonyl]-2-hydroxycarbamoyl-piperidine-4-carboxylic acid methyl ester


name: alpha-Sulfone piperidine hydroxamate, 1d


name: alpha-Sulfone piperidine hydroxamate, 1e


name: 1-{3-Hydroxycarbamoyl-2-[(4-methoxy-benzenesulfonyl)-methyl-amino]-benzyl}-pyrrolidine-2-carboxylic acid methyl ester


name: alpha-Sulfone piperidine hydroxamate, 1a


An N-sulfonylcarboxamide resulting from the formal condensation of the carboxy group of o-naphthalen-2-ylcinnamic acid with the sulfonamide group of 5-bromo-2-methoxybenzenesulfonamide. It is a selective antagonist for the prostanoid receptor EP3, a prostaglandin receptor for prostaglandin E2 (PGE2).


A member of the class of quinolines that is 7-methoxyquinoline substituted at position 4 by a (6-phenyl[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methoxy group. AMG exhibits antitumour activity, particularly in prostate cancer.


N-oleoylethanolamine phosphate

A N-acylethanolamine phosphate in which the acyl group is specifed as (9Z)-octadec-9-enoyl. It is a lysophosphatidic acid-1 (LPA1) receptor agonist.


SODIUM OXALATE

An organic sodium salt consisting of sodium and oxalate ions in a 2:1 ratio.


SODIUM CITRATE

The trisodium salt of citric acid.


name: Carbamimidothioic acid, 2-[(aminoiminomethyl)amino]ethyl ester, dihydrobromide (9CI)


An aralkylamino compound that is histamine bearing a methyl substituent at the 5 position on the ring.


cyclomulberrin

A extended flavonoid that is 6H,7H-chromeno[4,3-b]chromen-7-one which is substituted by a 2-methylprop-1-en-1-yl group at position 6, a 3-methylbut-2-en-1-yl group at position 11, and hydroxy groups at positions 3, 8, and 10. It is found in the bark of Morus species and has been reported to protect human neuronal cells derived from the human neuroblastoma SH-SY5Y cell line.


name: Trifluoro-methanesulfonic acid 8-(3-chloro-phenyl)-[1,7]naphthyridin-6-yl ester


CUDRAFLAVONE C

A tetrahydroxyflavone that is flavone substituted by hydroxy groups at positions 5, 7, 2' and 4' and prenyl groups at positions 3 and 6. Isolated from Morus nigra, it exhibits antibacterial and cytotoxic activities.


name: 3,5-Dimethyl-1-phenyl-1H-pyrazole-4-carboxylic acid ethyl ester


MORUSIN

An extended flavonoid that is flavone substituted by hydroxy groups at positions 5, 2' and 4', a prenyl group at position 3 and a 2,2-dimethyl pyran group across positions 7 and 8.


S-ROLIPRAM

The (S)-enantiomer of rolipram.


name: [4-(4-{2-[(S)-2-Hydroxy-3-(4-hydroxy-phenoxy)-propylamino]-ethyl}-phenylsulfamoyl)-phenyl]-carbamic acid methyl ester


name: (3-{2-[(R)-2-(3-Chloro-phenyl)-2-hydroxy-ethylamino]-propyl}-1H-indol-7-yloxy)-acetic acid methyl ester


name: [4-(4-{2-[(S)-2-Hydroxy-3-(4-hydroxy-phenoxy)-propylamino]-ethyl}-phenylsulfamoyl)-phenyl]-carbamic acid benzyl ester


name: [4-(4-{2-[(S)-2-Hydroxy-3-(4-hydroxy-phenoxy)-propylamino]-ethyl}-phenylsulfamoyl)-phenyl]-carbamic acid ethyl ester


name: Methanesulfonic acid 3-(2-{2-hydroxy-2-[(R)-3-(thiophene-2-sulfonylamino)-phenyl]-ethylamino}-ethyl)-1H-indol-7-yl ester


name: [4-(4-{2-[(S)-2-Hydroxy-3-(4-hydroxy-phenoxy)-propylamino]-ethyl}-phenylsulfamoyl)-phenyl]-carbamic acid isopropyl ester


name: Methanesulfonic acid 3-{(R)-2-[(R)-2-(3-allylamino-phenyl)-2-hydroxy-ethylamino]-propyl}-1H-indol-7-yl ester


name: Methanesulfonic acid 3-{(R)-2-[(R)-2-(3-but-2-ynylamino-phenyl)-2-hydroxy-ethylamino]-propyl}-1H-indol-7-yl ester


name: Methanesulfonic acid 3-{(R)-2-[(R)-2-hydroxy-2-(3-pent-2-enylamino-phenyl)-ethylamino]-propyl}-1H-indol-7-yl ester


name: [4-(4-{2-[(S)-2-Hydroxy-3-(4-hydroxy-phenoxy)-propylamino]-ethyl}-phenylsulfamoyl)-phenyl]-carbamic acid hexyl ester


name: Methanesulfonic acid 3-{(R)-2-[(R)-2-(3-benzylamino-phenyl)-2-hydroxy-ethylamino]-propyl}-1H-indol-7-yl ester


name: Methanesulfonic acid 3-{(R)-2-[(R)-2-(3-benzyloxy-phenyl)-2-hydroxy-ethylamino]-propyl}-1H-indol-7-yl ester


name: Methanesulfonic acid 3-((R)-2-{(R)-2-hydroxy-2-[3-(2-methyl-allylamino)-phenyl]-ethylamino}-propyl)-1H-indol-7-yl ester


name: (4-{4-[2-((R)-2-Hydroxy-2-pyridin-3-yl-ethylamino)-ethyl]-phenylsulfamoyl}-phenyl)-carbamic acid hexyl ester


name: (4-{4-[2-((R)-2-Hydroxy-2-pyridin-3-yl-ethylamino)-ethyl]-phenylsulfamoyl}-phenyl)-carbamic acid phenethyl ester


name: Methanesulfonic acid 3-{(R)-2-[(R)-2-(3-benzenesulfonylmethyl-phenyl)-2-hydroxy-ethylamino]-propyl}-1H-indol-7-yl ester


A member of the class of coumarins that is 2H-chromen-2-one substituted by 4-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)phenyl, methyl, and diethylamino groups at positions 3, 4 and 7, respectively. It is a thiol-reactive fluorescent dye.


A pyrazolone that is 5-methyl-4-methylene-2-(p-carboxyphenyl)-2,4-dihydro-3H-pyrazol-3-one in which the exocyclic carbon of the methylene group is attached to a 5-(4,5-dimethyl-2-nitrophenyl)furan-2-yl group by a single bond. C646 is a potent, cell permeable and selective competitive inhibitor of p300 and CBP (p300/CBP) histone acetyltransferases.


5-methyl-pyrazole-3-carboxylic acid

A memebr of the class of pyrazoles that is 1H-pyrazole with methyl and carboxylic acid group substituents at positions 5 and 3 respectively.


aminoacridine

Acridines which are substituted in any position by one or more amino groups or substituted amino groups. Note that the term 'aminoacridine' is the International Prorietary Name (INN) for 9-aminoacridine.


A dicarboxylic acid diamide obtained by condensation of the 3- and 4'-carboxy groups of 6-methyl[1,1'-biphenyl]-3,4'-dicarboxylic acid with cyclpropylamine and cyclpropylmethylamine respectively.


name: 1-Amino-2-phenylethylphosphonic acid monophenyl ester


name: Carbamic acid, ((1R,3aR,4aR,6R,8aR,9S,9aS)-9-((1E)-2-(2,3'-bipyridin)-6'-ylethenyl)dodecahydro-1-methyl-3-oxonaphtho(2,3-C)furan-6-yl)-, ethyl ester


name: 2-methyl-2-[3-((E)-2-nitro-vinyl)-phenoxy]-propionic acid ethyl ester


name: Naphthalen-1-yl-carbamic acid (1R,3S)-3-((R)-1-amino-2-oxo-2-thiazolidin-3-yl-ethyl)-cyclopentyl ester


name: (3-Fluoro-phenyl)-carbamic acid (1R,3S)-3-((R)-1-amino-2-oxo-2-thiazolidin-3-yl-ethyl)-cyclopentyl ester


name: (4-Methoxy-phenyl)-carbamic acid (1R,3S)-3-((S)-1-amino-2-oxo-2-pyrrolidin-1-yl-ethyl)-cyclopentyl ester


name: Biphenyl-2-yl-carbamic acid (1R,3S)-3-((S)-1-amino-2-oxo-2-pyrrolidin-1-yl-ethyl)-cyclopentyl ester


name: Synthesis of (E)-6-(2-((4-(furan-2-yl)-N-methylbenzamido)methyl)phenoxy)hex-2-enoic acid


A thienopyrimidine that is thieno[3,2-d]pyrimidine which is substituted by a (carboxymethyl)sulfanediyl group at position 4 and by a 4-(methylsulfanyl)phenyl group at position 6. It is a STK17B kinase inhibitor.


A thienopyrimidine that is thieno[3,2-d]pyrimidine which is substituted by a (carboxymethyl)sulfanediyl group at position 4 and by a 1-benzothiophen-2-yl group at position 6. It is a STK17B kinase inhibitor.


orantinib

An oxindole that is 3-methyleneoxindole in which one of the hydrogens of the methylene group is substituted by a 2-(2-carboxyethyl)-3,5-dimethylpyrrol-3-yl group. It is an ATP-competitive inhibitor of the tyrosine kinase activity of fibroblast growth factor receptor 1.


name: 2-AMINO-3-(4-HYDROXY-1,2,5-OXADIAZOL-3-YL)PROPIONIC ACID (STRUCTURAL MIX)


name: Succinic acid mono-[4-hydroxycarbamoyl-2-(4-phenoxy-benzoylamino)-pentyl] ester


name: 4-[4-(2,6,8,10-Tetraoxo-1,7,9-triaza-spiro[4.5]dec-1-yl)-phenoxy]-benzoic acid methyl ester


name: {5-[Hydroxycarbamoylmethyl-(4-nitro-benzyl)-sulfamoyl]-2-methoxy-phenyl}-carbamic acid tert-butyl ester


name: (S)-2-((E)-2-Hydroxycarbamoylmethyl-4-methyl-pent-2-enoylamino)-3-(1H-indol-3-yl)-propionic acid ethyl ester


name: 1-(Toluene-4-sulfonyl)-4-(toluene-4-sulfonyloxy)-pyrrolidine-2-carboxylic acid methyl ester


name: {4-[Hydroxycarbamoylmethyl-(4-nitro-benzyl)-sulfamoyl]-phenyl}-carbamic acid tert-butyl ester


name: 1-Benzenesulfonyl-4-benzenesulfonyloxy-pyrrolidine-2-carboxylic acid methyl ester


name: {3-[Hydroxycarbamoylmethyl-(4-nitro-benzyl)-sulfamoyl]-phenyl}-carbamic acid tert-butyl ester


caffeic acid

The trans-isomer of caffeic acid.


name: 4-{3-(Formyl-hydroxy-amino)-4-[4-(4-trifluoromethoxy-phenoxy)-benzenesulfonyl]-butyl}-benzoic acid methyl ester


name: 1-Benzenesulfonyl-4-(toluene-4-sulfonyloxy)-pyrrolidine-2-carboxylic acid methyl ester


name: 4-(3-Phenyl-acryloyloxy)-1-(toluene-4-sulfonyl)-pyrrolidine-2-carboxylic acid methyl ester


name: 4-Benzenesulfonyloxy-1-(toluene-4-sulfonyl)-pyrrolidine-2-carboxylic acid methyl ester


name: 4-[2-Hydroxycarbamoyl-1-(4-methoxy-benzenesulfonyl)-ethyl]-benzoic acid methyl ester


name: 1-Benzenesulfonyl-4-(3-phenyl-acryloyloxy)-pyrrolidine-2-carboxylic acid methyl ester


name: trans-4-Hydroxy-1-(toluene-4-sulfonyl)-pyrrolidine-2-carboxylic acid methyl ester


name: (S)-7-(Toluene-4-sulfonyl)-1,4-dioxa-7-aza-spiro[4.4]nonane-8-carboxylic acid methyl ester


name: 1-Methanesulfonyl-4-(toluene-4-sulfonyloxy)-pyrrolidine-2-carboxylic acid methyl ester


name: 4-Methanesulfonyloxy-1-(toluene-4-sulfonyl)-pyrrolidine-2-carboxylic acid methyl ester


name: (S)-2-(Toluene-4-sulfonyl)-6,10-dioxa-2-aza-spiro[4.5]decane-3-carboxylic acid methyl ester


name: (6S,7S)-7-hydroxycarbamoyl-6-(4-phenyl-piperidine-1-carbonyl)-5-aza-spiro[2.5]octane-5-carboxylic acid methyl ester


name: 1-Methanesulfonyl-4-(3-phenyl-acryloyloxy)-pyrrolidine-2-carboxylic acid methyl ester


name: 4-Benzenesulfonyloxy-1-methanesulfonyl-pyrrolidine-2-carboxylic acid methyl ester


name: trans-1-Benzenesulfonyl-4-hydroxy-pyrrolidine-2-carboxylic acid methyl ester


name: Phosphoric acid 3-(4-pyren-1-yl-butyrylamino)-propyl ester (1R,2R,3S,4R,5R,6S)-2,3,6-trihydroxy-4,5-bis-phosphonooxy-cyclohexyl ester


name: Phosphoric acid 3-[(naphthalene-1-carbonyl)-amino]-propyl ester (1R,2R,3S,4R,5R,6S)-2,3,6-trihydroxy-4,5-bis-phosphonooxy-cyclohexyl ester


name: Phosphoric acid 3-{4-[bis-(4-dimethylamino-phenyl)-methyl]-benzoylamino}-propyl ester (1R,2R,3S,4R,5R,6S)-2,3,6-trihydroxy-4,5-bis-phosphonooxy-cyclohexyl ester


name: Phosphoric acid 3-amino-propyl ester (1R,2R,3S,4R,5R,6S)-2,3,6-trihydroxy-4,5-bis-phosphonooxy-cyclohexyl ester


TRIDOLGOSIR

An indolizidine alkaloid isolated from the plant Swainsona canescens with three hydroxy substituents at positions 1, 2 and 8.


name: 4-(2,5-Dioxo-3-phenyl-imidazolidine-1-sulfonyl)-benzoic acid methyl ester


name: 3-(2,5-Dioxo-3-phenyl-imidazolidine-1-sulfonyl)-benzoic acid methyl ester


name: (S)-2-[3-(4-Cyano-benzoylamino)-2,2-dimethyl-nonanoylamino]-3-phenyl-propionic acid isopropyl ester


name: 4-(5-Chloro-3-methyl-benzo[b]thiophene-2-sulfonylamino)-3-methanesulfonyl-benzoic acid methyl ester


name: (S)-2-[3-(4-Cyano-benzoylamino)-2,2-dimethyl-nonanoylamino]-3-phenyl-propionic acid ethyl ester


name: 3-Methanesulfonyl-4-(3-methyl-benzo[b]thiophene-2-sulfonylamino)-benzoic acid methyl ester


name: 4-(3,5-Dimethyl-benzo[b]thiophene-2-sulfonylamino)-3-methanesulfonyl-benzoic acid methyl ester


name: [3-(2,5-Dioxo-3-phenyl-imidazolidine-1-sulfonyl)-phenyl]-acetic acid methyl ester


name: 4-(5-Chloro-3-methyl-benzo[b]thiophene-2-sulfonylamino)-3-methanesulfonyl-2-methyl-benzoic acid methyl ester


name: 4-(5-Chloro-3-methyl-benzo[b]thiophene-2-sulfonylamino)-3-nitro-benzoic acid methyl ester


DELANZOMIB

A C-terminal boronic acid peptide inhibitor which induces apoptosis in multiple myeloma, hematological and solid tumor cell lines.


name: (S)-2-[3-(4-Cyano-benzoylamino)-2,2-dimethyl-nonanoylamino]-3-phenyl-propionic acid propyl ester


A member of the class of isoquinolines that is the sulfonamide obtained by formal condensation of the sulfo group of isoquinoline-5-sulfonic acid with the primary amino group of N(1)-[3-(4-bromophenyl)prop-2-en-1-yl]ethane-1,2-diamine. It is a protein kinase A inhibitor.


fumagillin

A meroterpenoid resulting from the formal condensation of the hydroxy group of fumagillol with the carboxylic acid group of (all-E)-deca-2,4,6,8-tetraenedioic acid. Originally isolated from the fungus Aspergillus fumigatus, it is used for the control of Nosema infection in honey bees.


O-CHLOROACETYLCARBAMOYLFUMAGILLOL

A carbamate ester that is fumagillol in which the hydroxy group has been converted to the corresponding N-(chloroacetyl)carbamate derivative.


name: 5,6-Disubstituted anthranilic acid sulfonamide, 9i


name: 5,6-Disubstituted anthranilic acid sulfonamide, 19d


name: 5,6-Disubstituted anthranilic acid sulfonamide, 9h


name: 5,6-Disubstituted anthranilic acid sulfonamide, 19i


name: 5,6-Disubstituted anthranilic acid sulfonamide, 19f


name: 5,6-Disubstituted anthranilic acid sulfonamide, 9n


name: 5,6-Disubstituted anthranilic acid sulfonamide, 19a


name: 5,6-Disubstituted anthranilic acid sulfonamide, 19h


name: 5,6-Disubstituted anthranilic acid sulfonamide, 19e


name: 5,6-Disubstituted anthranilic acid sulfonamide, 9j


name: 5,6-Disubstituted anthranilic acid sulfonamide, 19c


name: 5,6-Disubstituted anthranilic acid sulfonamide, 19g


name: 5,6-Disubstituted anthranilic acid sulfonamide, 16a


name: 5,6-Disubstituted anthranilic acid sulfonamide, 9o


name: 5,6-Disubstituted anthranilic acid sulfonamide, 9b


name: (R)-2-((R)-3-Amino-5-ethylsulfanyl-2-hydroxy-pentanoylamino)-propionic acid ethyl ester


name: 5,6-Disubstituted anthranilic acid sulfonamide, 9d


name: 5,6-Disubstituted anthranilic acid sulfonamide, 9m


name: (S)-2-((R)-3-Amino-2-hydroxy-5-phenyl-pentanoylamino)-propionic acid ethyl ester


name: (S)-2-((R)-3-Amino-5-cyclohexyl-2-hydroxy-pentanoylamino)-propionic acid ethyl ester


name: (S)-2-((2S,3R)-3-Amino-4-cyclohexyl-2-hydroxy-butyrylamino)-propionic acid ethyl ester


name: (S)-2-((R)-3-Amino-4-cyclohexyl-2-hydroxy-butyrylamino)-propionic acid ethyl ester


name: 2-((2S,3R)-3-Amino-4-cyclohexyl-2-hydroxy-butyrylamino)-2-methyl-propionic acid ethyl ester


name: 5,6-Disubstituted anthranilic acid sulfonamide, 9k


MMP9 inhibitor I

A hydroxamic acid that is N-hydroxy-3-methylbenzamide in which the the hydrogens at positions 2 and 5 have been replaced by benzyl[(4-methoxyphenyl)sulfonyl]amino and (diethylamino)methyl groups, respectively. It is a cell-permeable, potent, selective, and reversible inhibitor of matrix metallopeptidase-9 (MMP-9, EC 3.4.24.35).


name: ((R)-3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquinolin-2-yl)-(4-methoxy-phenyl)-phosphinic acid ethyl ester


name: {2-[3-Hydroxycarbamoyl-4-(4-methoxy-benzenesulfonyl)-[1,4]diazepan-1-yl]-2-oxo-ethyl}-carbamic acid tert-butyl ester


name: ((R)-3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquinolin-2-yl)-p-tolyl-phosphinic acid ethyl ester


name: ((R)-3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquinolin-2-yl)-phenyl-phosphinic acid ethyl ester


name: (4-Fluoro-phenyl)-((R)-3-hydroxycarbamoyl-3,4-dihydro-1H-isoquinolin-2-yl)-phosphinic acid ethyl ester


name: ((S)-3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquinolin-2-yl)-(4-methoxy-phenyl)-phosphinic acid ethyl ester


dacarbazine

A dacarbazine in which the N=N double bond adopts a trans-configuration.


name: {(R)-3-[(S)-2-(1H-Indol-3-yl)-1-methylcarbamoyl-ethylcarbamoyl]-5-methyl-hexanoylaminooxy}-acetic acid methyl ester


name: (S)-3-(Hydroxyaminooxalyl-amino)-N-((S)-1-phenyl-ethyl)-succinamic acid benzyl ester


imetit dihydrobromide

A hydrobromide salt obtained by reaction of imetit with two equivalents of hydrobromic acid. An extremely potent, high affinity agonist at H3 and H4 receptors (Ki values are 0.3 and 2.7 nM respectively). Induces shape change in eosinophils with an EC50 of 25 nM. Centrally active following systemic administration.


(R)-alpha-methylhistamine

An aralkylamino compound that is histamine bearing a methyl substituent at the alpha-position (the R-enantiomer).


name: Dicyclopropylmethyl-carbamic acid 3-(1H-imidazol-4-yl)-propyl ester;C2H2O4


name: (R)(1-Cyclohexyl-ethyl)-carbamic acid 3-(1H-imidazol-4-yl)-propyl ester


name: 4-(4-Iodo-phenyl)-butyric acid 3-(1H-imidazol-4-yl)-propyl ester


name: Phosphoric acid 2-{(2S,3S)-2-[2-(5-benzyloxy-1H-indol-3-yl)-acetylamino]-3-methyl-pentanoylamino}-ethyl ester (S)-2-(3-hydroxy-hexadecylcarbamoyl)-2-icosanoylamino-ethyl ester


name: Phosphoric acid (S)-2-(3-hydroxy-hexadecylcarbamoyl)-2-icosanoylamino-ethyl ester 2-[(2S,3S)-2-(2-1H-indol-3-yl-acetylamino)-3-methyl-pentanoylamino]-ethyl ester


N-Acetylneuraminic acid reduced across the 2,3-bond with loss of the hydroxy group at C-2; it is a minor component of body fluids although abundant in sialuria.


DEOXYFUCONOJIRIMYCIN

A hydroxypiperidine in which the three hydroxy substituents are located at positions 3, 4 and 5 together with an additional methyl substituent at position 2.


name: {[(3,4,5-Trihydroxy-2-hydroxymethyl-6-methyl-piperidin-2-ylmethyl)-carbamoyl]-methyl}-carbamic acid benzyl ester


phosphoenolpyruvic acid

A monocarboxylic acid that is acrylic acid substituted by a phosphonooxy group at position 2. It is a metabolic intermediate in pathways like glycolysis and gluconeogenesis.


thiram

An organic disulfide that results from the formal oxidative dimerisation of N,N-dimethyldithiocarbamic acid. It is widely used as a fungicidal seed treatment.


A potent cell-permeable and bivalent Smac mimetic which binds to XIAP, cIAP-1 and cIAP-2 proteins (Ki = 0.56 nM,  0.31 nM and 1.1 nM, respectively). It induces apoptosis and tumor regression in cancer xenograft models.


name: US9669031, 51 N-[6-[[8-chloro-3-(3-chlorophenyl)-3-methyl-1,5-dioxo-2H-imidazo[1,5-a]pyridin-6-yl]amino]pyrimidin-4-yl]cyclopropanecarboxamide (Cpd. No. 51)


name: US9669031, 109 8-chloro-6-(pyrimidin-4-ylamino)spiro[2H-imidazo[1,5-a]pyridine-3,1'-cyclohexane]-1,5-dione hydrochloride (Cpd. No. 109)


name: US9669031, 207 6'-((6-aminopyrimidin-4-yl)amino)-8'-(hydroxymethyl)-2'H-spiro[cyclohexane-1,3'-imidazo[1,5-a]pyridine]-1',5'-dione (Cpd. No. 207)


name: US9669031, 10 N-(6-((3,3-dimethyl-1,5-dioxo-1,2,3,5-tetrahydroimidazo[1,5-a]pyridin-6-yl)amino)pyrimidin-4-yl)cyclopropanecarboxamide (Cpd. No. 10)


name: US9669031, 69 8-fluoro-3,3-dimethyl-6-(pyrimidin-4-ylamino)-2H-imidazo[1,5-a]pyridine-1,5-dione (Cpd. No. 69)


name: 2-methyl-2-{[(2S)-4-methyl-2-({[4-(trifluoromethyl)phenyl]carbamoyl} amino)pentanoyl]amino} propanoic acid


name: (R)-3-(3-Cyano-pyridin-2-ylamino)-pyrrolidine-1-carboxylic acid 5-carbamoyl-adamantan-2-yl ester


name: (S)-3-(3-Trifluoromethyl-pyridin-2-ylamino)-pyrrolidine-1-carboxylic acid 5-carbamoyl-adamantan-2-yl ester


name: (R)-3-(3-Trifluoromethyl-pyridin-2-ylamino)-pyrrolidine-1-carboxylic acid 5-carbamoyl-adamantan-2-yl ester


name: (R)-3-(6-Trifluoromethyl-pyridin-2-ylamino)-pyrrolidine-1-carboxylic acid 5-carbamoyl-adamantan-2-yl ester


name: (S)-3-(5-Trifluoromethyl-pyridin-2-ylamino)-pyrrolidine-1-carboxylic acid 5-carbamoyl-adamantan-2-yl ester


name: (R)-3-(5-Trifluoromethyl-pyridin-2-ylamino)-pyrrolidine-1-carboxylic acid 5-carbamoyl-adamantan-2-yl ester


name: (R)-3-(5-Cyano-pyridin-2-ylamino)-pyrrolidine-1-carboxylic acid 5-carbamoyl-adamantan-2-yl ester


name: (S)-3-(5-Cyano-pyridin-2-ylamino)-pyrrolidine-1-carboxylic acid 5-carbamoyl-adamantan-2-yl ester


name: (R)-3-(2-Trifluoromethyl-pyrimidin-4-ylamino)-pyrrolidine-1-carboxylic acid 5-carbamoyl-adamantan-2-yl ester


name: (S)-3-(3-Cyano-pyridin-2-ylamino)-pyrrolidine-1-carboxylic acid 5-carbamoyl-adamantan-2-yl ester


name: (R)-3-(tert-Butoxycarbonyl-methyl-amino)-pyrrolidine-1-carboxylic acid adamantan-2-yl ester


name: (R)-3-(4-Trifluoromethyl-pyridin-2-ylamino)-pyrrolidine-1-carboxylic acid 5-carbamoyl-adamantan-2-yl ester


name: (R)-3-tert-Butoxycarbonylamino-pyrrolidine-1-carboxylic acid 5-carbamoyl-adamantan-2-yl ester


name: (R)-3-tert-Butoxycarbonylamino-pyrrolidine-1-carboxylic acid 5-hydroxy-adamantan-2-yl ester


name: (S)-3-tert-Butoxycarbonylamino-pyrrolidine-1-carboxylic acid 5-carbamoyl-adamantan-2-yl ester


name: Piperidine-1-carboxylic acid adamantan-2-yl ester


name: (R)-3-(4-Trifluoromethyl-pyrimidin-2-ylamino)-pyrrolidine-1-carboxylic acid 5-carbamoyl-adamantan-2-yl ester


name: (R)-3-Propoxycarbonylamino-pyrrolidine-1-carboxylic acid adamantan-2-yl ester


name: (R)-3-tert-Butoxycarbonylamino-pyrrolidine-1-carboxylic acid 5-hydroxymethyl-adamantan-2-yl ester


glycyrrhizin

A  triterpenoid saponin that is the  glucosiduronide derivative of 3beta-hydroxy-11-oxoolean-12-en-30-oic acid.


name: (R)-3-Isopropoxycarbonylamino-pyrrolidine-1-carboxylic acid adamantan-2-yl ester


name: (R)-3-tert-Butoxycarbonylamino-pyrrolidine-1-carboxylic acid 5-cyano-adamantan-2-yl ester


enoxolone

A pentacyclic triterpenoid that is olean-12-ene substituted by a hydroxy group at position 3, an oxo group at position 11 and a carboxy group at position 30.


name: (R)-3-Benzyloxycarbonylamino-pyrrolidine-1-carboxylic acid adamantan-2-yl ester


name: (R)-3-(Benzyl-tert-butoxycarbonyl-amino)-pyrrolidine-1-carboxylic acid adamantan-2-yl ester


name: (R)-3-tert-Butoxycarbonylamino-pyrrolidine-1-carboxylic acid 5-acetylamino-adamantan-2-yl ester


name: (R)-3-(2,6-Dimethyl-pyrimidin-4-ylamino)-pyrrolidine-1-carboxylic acid 5-carbamoyl-adamantan-2-yl ester


name: (R)-3-(5-Trifluoromethyl-[1,3,4]thiadiazol-2-ylamino)-pyrrolidine-1-carboxylic acid 5-carbamoyl-adamantan-2-yl ester


name: 4-(2-Fluoro-benzenesulfonylamino)-a damantane-1-carboxylic acid amide


name: 4-[2-(3-Benzoyl-4-hydroxy-1,1-dioxo-1H-1lambda*6*-benzo[e][1,2]thiazin-2-yl)-acetyl]-benzoic acid methyl ester


name: 4-Phenyl-piperidine-1,4-dicarboxylic acid 1-adamantan-2-ylamide 4-amide


name: (R)-3-(3,3-Dimethyl-butyrylamino)-pyrrolidine-1-carboxylic acid adamantan-2-yl ester


name: (R)-3-tert-Butoxycarbonylamino-pyrrolidine-1-carboxylic acid 5-(1-hydroxy-1-methyl-ethyl)-adamantan-2-yl ester


name: 3,3-Dimethyl-pentanedioic acid adamantan-2-ylamide cyclopropylamide


name: 4-{[3-(3,4-Dichloro-benzenesulfonyl)-thiazolidine-2-carbonyl]-amino}-adamantane-1-carboxylic acid methyl ester


name: (R)-3-tert-Butoxycarbonylamino-pyrrolidine-1-carboxylic acid 5-methoxycarbonyl-adamantan-2-yl ester


name: Tert-butyl 6-(2-(adamantan-2-yl amino)-2-oxoethyl)-1,2,6-thiadiazinan-2-carboxylate 1,1-dioxide


name: 2-(Adamantan-2-ylcarbamoyl)-thiazolidine-3-carboxylic acid tert-butyl ester


A 11alpha-hydroxy steroid that is pregn-4-ene-3,20-dione substituted by a hydroxy group at position 11.


name: Thiazolidine-2,3-dicarboxylic acid 2-adamantan-2-ylamide 3-phenylamide


name: Preparation of 2-(7-(5-chloro-4-(2-(isopropylsulfonyl)phenylamino)pyrimidin-2 yl)amino)-6-methoxy-3,4-dihydroisoquinolin-2(1H)-yl)-N, N-dimethylacetamide


stattic

A member of the class of 1-benzothiophenes that is 1-benzothiophene-1,1-dioxide substituted at position 6 by a nitro group. Used as a radiosensitising agent for esophageal squamous cell carcinoma.


name: 3-[2-(4-Adamant-1-yl-phenoxy)-acetylamino]-benzoic acid methyl ester


name: (E)-3-[3-(4-Adamantan-1-yl-phenoxy)-acryloylamino]-benzoic acid methyl ester


EUFLAVINE

The 10-methochloride salt of 3,6-diaminoacridine. Note that a mixture of this compound with 3,6-diaminoacridine (proflavine) is known as acriflavine or neutral acriflavine.


name: (7S)-1 inverted exclamation marka-{[5-(trifluoromethyl)furan-2-yl]methyl}spiro[furo[2,3-f][1,3]benzodioxole-7,3 inverted exclamation marka-indol]-2 inverted exclamation marka(1 inverted exclamation markaH)-one


name: Pentanedioic acid ([2,2'''']bithiophenyl-5-ylmethyl)-amide (2''''-sulfamoyl-biphenyl-4-ylmethyl)-amide


A 7-hydroxyflavonol that is kaempferide substituted by a 1,1-dimethylallyl group at position 8.


NORVERAPAMIL

A secondary amino compound that is 3,4-dimethoxyphenylethylamine in which one of the hydrogens attached to the nitrogen has been replaced by a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.


Fumitremorgin C

An organic heteropentacyclic compound that is a mycotoxic indole alkaloid produced by several fungi. A potent and specific inhibitor of the breast cancer resistance protein multidrug transporter.


A trihydroxyflavone that is galangin substituted by a 1,1-dimethylallyl moiety at position 8. It is isolated from the buds of Platanus acerifolia.


name: [2''-(1-Carbamoyl-3-methyl-butylcarbamoyl)-biphenyl-2-ylmethyl]-carbamic acid benzyl ester


name: {2-[2-(Cyclopropylmethyl-carbamoyl)-pyridin-3-yl]-benzyl}-carbamic acid 1-phenyl-ethyl ester


name: [6,6''-Dimethyl-2''-(2-pyridin-2-yl-ethylcarbamoyl)-biphenyl-2-ylmethyl]-carbamic acid benzyl ester


name: [2''-(3-Methyl-butylcarbamoyl)-biphenyl-2-ylmethyl]-carbamic acid benzyl ester


name: [2''-(2,4-Difluoro-benzylcarbamoyl)-biphenyl-2-ylmethyl]-carbamic acid benzyl ester


name: {2-[2-(3-Methyl-butylcarbamoyl)-pyridin-3-yl]-benzyl}-carbamic acid benzyl ester


name: [2''-(3-Methyl-butylcarbamoyl)-biphenyl-2-ylmethyl]-carbamic acid tert-butyl ester


name: {4-[2-(3-Methyl-butylcarbamoyl)-phenyl]-pyridin-3-ylmethyl}-carbamic acid benzyl ester


name: {2-[3-(3-Methyl-butylcarbamoyl)-pyridin-2-yl]-benzyl}-carbamic acid benzyl ester


name: 4''-{[3-(3,3,3-Trifluoro-propionylamino)-pyridin-2-ylamino]-methyl}-biphenyl-2-carboxylic acid methyl ester


name: 2-(4-{[3-(2-Cyano-acetylamino)-4-methyl-pyridin-2-ylamino]-methyl}-piperidin-1-yl)-benzoic acid methyl ester


name: 2-(4-{[3-(2-Cyano-acetylamino)-4-methyl-pyridin-2-ylamino]-methyl}-cyclohex-1-enyl)-benzoic acid methyl ester


name: 2-(4-{[3-(2-Cyano-acetylamino)-4-methyl-pyridin-2-ylamino]-methyl}-phenyl)-cyclohex-1-enecarboxylic acid methyl ester


name: (S)-alpha-[[[4-bromo-5-[(2-chlorobenzoyl)amino]-1H-pyrazol-3-yl]carbonyl]amino]benzeneacetic acid methyl ester


name: [[4-(6-Aminopurin-9-yl)-2,3-dihydroxy-1-bicyclo[3.1.0]hexanyl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate


name: (S)-2-(4-Diisopropylcarbamoyl-2-isopropoxy-benzoylamino)-4-methyl-pentanoic acid methyl ester


An aromatic amide obtained by formal condensation of the amino group of 2-(6-methoxy-1-oxo-1,3-dihydro-2H-isoindol-2-yl)-1,3-thiazole-4-carboxylic acid with the primary amino group of 4-(piperazin-1-yl)pyridin-3-amine.


name: Methyl-carbamic acid 4-[(2-methoxy-benzoylamino)-methyl]-4-phenyl-cyclohexyl ester


name: Propyl-carbamic acid 4-[(2-methoxy-benzoylamino)-methyl]-4-phenyl-cyclohexyl ester


name: Allyl-carbamic acid 4-[(2-methoxy-benzoylamino)-methyl]-4-phenyl-cyclohexyl ester


name: Allyl-carbamic acid 4-[(5-fluoro-2-methoxy-benzoylamino)-methyl]-4-phenyl-cyclohexyl ester


name: {4-[(2-Methoxy-benzoylamino)-methyl]-4-phenyl-cyclohexyl}-carbamic acid allyl ester


name: Isopropyl-carbamic acid 4-[(2-methoxy-benzoylamino)-methyl]-4-phenyl-cyclohexyl ester


name: (2-Methyl-allyl)-carbamic acid 4-[(2-methoxy-benzoylamino)-methyl]-4-phenyl-cyclohexyl ester


name: Butyl-carbamic acid 4-[(2-methoxy-benzoylamino)-methyl]-4-phenyl-cyclohexyl ester


name: (2-Hydroxy-ethyl)-carbamic acid 4-[(2-methoxy-benzoylamino)-methyl]-4-phenyl-cyclohexyl ester


name: Carbamic acid 4-[(2-methoxy-benzoylamino)-methyl]-4-phenyl-cyclohexyl ester


name: Phenyl-carbamic acid 4-[(2-methoxy-benzoylamino)-methyl]-4-phenyl-cyclohexyl ester


name: (3-Methoxy-propyl)-carbamic acid 4-[(2-methoxy-benzoylamino)-methyl]-4-phenyl-cyclohexyl ester


name: {4-[(2-Methoxy-benzoylamino)-methyl]-4-phenyl-cyclohexyl}-carbamic acid methyl ester


name: Allyl-carbamic acid 4-[(5-fluoro-2-hydroxy-benzoylamino)-methyl]-4-phenyl-cyclohexyl ester


name: (2-Methoxy-ethyl)-carbamic acid 4-[(2-methoxy-benzoylamino)-methyl]-4-phenyl-cyclohexyl ester


name: Allyl-methyl-carbamic acid 4-[(2-methoxy-benzoylamino)-methyl]-4-phenyl-cyclohexyl ester


name: {4-[(2-Methoxy-benzoylamino)-methyl]-4-phenyl-cyclohexyl}-thiocarbamic acid methyl ester


name: Diallyl-carbamic acid 4-[(2-methoxy-benzoylamino)-methyl]-4-phenyl-cyclohexyl ester


name: Allyl-carbamic acid 4-[(5-chloro-2-methoxy-benzoylamino)-methyl]-4-phenyl-cyclohexyl ester


name: Carbonic acid allyl ester 4-[(2-methoxy-benzoylamino)-methyl]-4-phenyl-cyclohexyl ester


name: Benzyl-carbamic acid 4-[(2-methoxy-benzoylamino)-methyl]-4-phenyl-cyclohexyl ester


name: Allyl-carbamic acid 4-{[(2-methoxy-pyridine-3-carbonyl)-amino]-methyl}-4-phenyl-cyclohexyl ester


name: Phenethyl-carbamic acid 4-[(2-methoxy-benzoylamino)-methyl]-4-phenyl-cyclohexyl ester


name: (3-Phenyl-propyl)-carbamic acid 4-[(2-methoxy-benzoylamino)-methyl]-4-phenyl-cyclohexyl ester


name: 4-Piperidinecarboxylic acid, 1-(3-cyano-3,3-diphenylpropyl)-4-phenyl-, methyl ester


name: Allyl-carbamic acid 4-{[(2,3-dihydro-benzofuran-7-carbonyl)-amino]-methyl}-4-phenyl-cyclohexyl ester


NALANTHALIDE

A pyranone diterpenoid isolated from Nalanthamala and Chaunopycnis alba and has been shown to be a blocker of the voltage-gated potassium channel Kv1.3


name: Allyl-carbamic acid 4-[(3-chloro-2-hydroxy-benzoylamino)-methyl]-4-phenyl-cyclohexyl ester


name: Allyl-carbamic acid 4-[(3-chloro-2-methoxy-benzoylamino)-methyl]-4-phenyl-cyclohexyl ester


name: {5-[4-(Benzylcarbamoyl-methyl)-3-biphenyl-4-yl-3,4-dihydro-quinazolin-2-ylamino]-pentyl}-carbamic acid tert-butyl ester


name: 2-(4-Bromo-phenyl)-2-isopropyl-5-[4-(3-methyl-benzyl)-piperazin-1-yl]-pentanoic acid methyl ester


name: 2-(3-methyl-benzyl)-1,3-dioxo-2,3-dihydro-1H-isoindole-5-carboxylic acid (2-piperidin-1-yl-ethyl)-amide hydrochloride


name: 2-(4-methyl-benzyl)-1,3-dioxo-2,3-dihydro-1H-isoindole-5-carboxylic acid (2-piperidin-1-yl-ethyl)-amide hydrochloride


name: 2-(2-methyl-benzyl)-1,3-dioxo-2,3-dihydro-1H-isoindole-5-carboxylic acid (2-piperidin-1-yl-ethyl)-amide hydrochloride


(-)-CATECHINGALLATE

A gallate ester obtained by formal condensation of the carboxy group of gallic acid with the (3R)-hydroxy group of (-)-catechin.


LACTACYSTIN

L-Cysteine substituted at nitrogen by an acetyl group and at sulfur by a substituted-lactam carbonyl group.


GALLOCATECHIN GALLATE

A gallate ester obtained by formal condensation of the carboxy group of gallic acid with the (3R)-hydroxy group of (-)-gallocatechin. A natural product found in found in green tea.


syringolin A

A syrbactin that has a (3E,9E)-2,7-dioxo-1,6-diazacyclododeca-3,9-diene skeleton that is substituted by an isopropyl group at position 5 and by a [(2S)-2-({[(1S)-1-carboxy-2-methylpropyl]carbamoyl}amino)-3-methylbutanoyl]nitrilo group at the 8-pro-S position. It is produced by the pathogenic bacterium Pseudomonas syringae pv. syringae.


Indole-3-acetic acid substituted on nitrogen with a 4-chlorobenzoyl group and at C-5 by a methoxy group.


6-METHOXY-2-NAPHTHYLACETIC ACID

A monocarboxylic acid consisting of 2-naphthylacetic acid having a methoxy substituent at the 6-position. The active metabolite of the prodrug nabumetone.


M-PHENOXYBENZOIC ACID FOR CIS-ISOMER

A phenoxybenzoic acid in which the phenoxy group is meta to the carboxy group. It is a metabolite of pyrethroid insecticides.


LAPACHONE

A benzochromenone that is 3,4-dihydro-2H-benzo[h]chromene-5,6-dione substituted by geminal methyl groups at position 2. Isolated from Tabebuia avellanedae, it exhibits antineoplastic and anti-inflammatory activities.


A glutathione conjugate in which the mercapto hydrogen of glutathione has been replaced by a 1,4-dihydroxy-3-methylnaphthalen-2-yl group


NAPHTHOQUINONE

The parent structure of the family of 1,4-naphthoquinones, in which the oxo groups of the quinone moiety are at positions 1 and 4 of the naphthalene ring. Derivatives have pharmacological properties.


A naphthoquinone that is naphthalene-1,4-dione substituted by a methoxy group at position 2. It has been isolated from the roots of Rubia yunnanensis.


JUGLONE

A hydroxy-1,4-naphthoquinone that is 1,4-naphthoquinone in which the hydrogen at position 5 has been replaced by a hydroxy group. A plant-derived 1,4-naphthoquinone with confirmed antibacterial and antitumor activities.


name: {Isobutyryl-[4-(2,2,2-trifluoro-1-hydroxy-1-trifluoromethylethyl)phenyl]amino}acetic acid methyl ester


name: 5-{(Morpholine-4-carbonyl)-[4-(2,2,2-trifluoro-1-hydroxy-1-trifluoromethylethyl)phenyl]amino}pentanoic acid methyl ester


name: 4-{(Morpholine-4-carbonyl)-[4-(2,2,2-trifluoro-1-hydroxy-1-trifluoromethylethyl)phenyl]amino}butyric acid methyl ester


name: {(Morpholine-4-carbonyl)-[4-(2,2,2-trifluoro-1-hydroxy-1-trifluoromethylethyl)phenyl]amino}acetic acid methyl ester


name: 3-{(Morpholine-4-carbonyl)-[4-(2,2,2-trifluoro-1-hydroxy-1-trifluoromethylethyl)phenyl]amino}propionic acid methyl ester


name: {(3-Phenylpropionyl)-[4-(2,2,2-trifluoro-1-hydroxy-1-trifluoromethylethyl)phenyl]amino}acetic acid methyl ester


name: N4-Benzyloxycytidine 5''-Diphosphate triethylammonium Salt


name: [(1S,2R,3R,4S,5S)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxy-2-bicyclo[3.1.0]hexanyl]methyl phosphono hydrogen phosphate


voriconazole

A triazole-based antifungal agent used for the treatment of esophageal candidiasis, invasive pulmonary aspergillosis, and serious fungal infections caused by Scedosporium apiospermum and Fusarium spp. It is an inhibitor of cytochrome P450 2C9 (CYP2C9) and CYP3A4.


name: 4-[(3-Phosphono-propylamino)-methyl]-benzoic acid heptyl ester


name: [(2S)-2-amino-3-(4-octylanilino)-3-oxopropyl] dihydrogen phosphate;2,2,2-trifluoroacetic acid


name: 3-(2-Amino-4-oxo-4,5-dihydro-3H-pyrrolo[3,2-d]pyrimidin-7-yl)-3-(3-chloro-phenyl)-propionic acid methyl ester


name: N-[(2S,3R)-2-Methyl-4-oxooxetane-3-yl]carbamic acid 5-phenylpentyl ester


(-)-marinopyrrole A

A member of the class of pyrroles that is 1'H-1,3'-bipyrrole substituted by four chloro groups at positions 4, 4', 5 and 5' and two 2-hydroxybenzoyl moieties at positions 2 and 2'. It is isolated from Streptomyces sp.CNQ-418 and exhibits cytotoxic and antibacterial activities.


anthragallol

A trihydroxyanthraquinone that is anthracene-9,10-dione substituted by hydroxy groups at positions 1, 2 and 3.


name: (4-Biphenyl-4-yl-thiophene-2-carbonyl)-carbamic acid 4-methyl-benzyl ester


name: [4-(4-Trifluoromethoxy-phenyl)-thiophene-2-carbonyl]-carbamic acid 4-methyl-cyclohexyl ester


name: [4-(4-Trifluoromethoxy-phenyl)-thiophene-2-carbonyl]-carbamic acid 4-methyl-benzyl ester


A member of the class of guanidines in which the imino hydrogen of guanidine itself has been replaced by a 7-aminoheptyl group. It is an inhibitor of deoxyhypusine synthase activity (GO:0034038).


name: (S)-3-(4-((3-((Isopropyl(thiophen-3-ylmethyl)amino)methyl)benzyl)oxy)phenyl)hex-4-ynoic acid Calcium Salt


name: (1-Aminooxalyl-3-biphenyl-2-ylmethyl-2-methyl-indolizin-8-yloxy)-acetic acid methyl ester


name: (1-Aminooxalyl-3-biphenyl-2-ylmethyl-2-ethyl-indolizin-8-yloxy)-acetic acid methyl ester


name: (1-Aminooxalyl-3-cyclohexylmethyl-2-cyclopropyl-indolizin-8-yloxy)-acetic acid methyl ester


name: (1-Aminooxalyl-2-ethyl-3-phenethyl-indolizin-8-yloxy)-acetic acid methyl ester


name: 2-Chloro-5-{2-methoxy-6-[2-(4-methoxy-phenyl)-ethylamino]-pyrimidin-4-yl)-benzoic acid ethyl ester


name: N''-[3-(4-acetyl-piperazin-1-ylmethyl)-2-phenyl-quinoline-4-carbonyl]-N-phenyl-hydrazinecarboxylic acid methyl ester


name: N-(3-fluoro-phenyl)-N''-(3-methoxy-2-phenyl-quinoline-4-carbonyl)-hydrazinecarboxylic acid methyl ester


name: [(R)-2-(2-Fluoro-phenyl)-1-methyl-1-(7-ureido-heptylcarbamoyl)-ethyl]-carbamic acid (S)-2-methyl-1-phenyl-propyl ester


fezolinetant

A triazolopyrazine that is 5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-a]pyrazine substituted by 3-methyl-1,2,4-thiadiazol-5-yl, 4-fluorobenzoyl and methyl groups at positions 3, 7, and 8R, respectively. It is a prescription medicine used to reduce moderate to severe vasomotor symptoms due to menopause.


name: Phenyl-[(2-thiophen-3-yl-quinoline-4-carbonyl)-amino]-acetic acid methyl ester


name: Phenyl-[(2-phenyl-quinoline-4-carbonyl)-amino]-acetic acid methyl ester


name: N-(4-fluoro-phenyl)-N''-(3-methoxy-2-phenyl-quinoline-4-carbonyl)-hydrazinecarboxylic acid methyl ester


name: [(R)-1-Methyl-2-phenyl-1-(7-ureido-heptylcarbamoyl)-ethyl]-carbamic acid (S)-2-methyl-1-phenyl-propyl ester


name: Phenyl-{[2-(1H-pyrrol-2-yl)-quinoline-4-carbonyl]-amino}-acetic acid methyl ester


name: [(R)-1-(8-Hydroxy-octylcarbamoyl)-1-methyl-2-phenyl-ethyl]-carbamic acid (S)-2-methyl-1-phenyl-propyl ester


name: N-(2-fluoro-phenyl)-N''-(3-methoxy-2-phenyl-quinoline-4-carbonyl)-hydrazinecarboxylic acid methyl ester


name: [(7-Methoxy-2-phenyl-quinoline-4-carbonyl)-amino]-phenyl-acetic acid methyl ester


name: N''-(3-methoxy-2-phenyl-quinoline-4-carbonyl)-N-phenyl-hydrazinecarboxylic acid ethyl ester


name: Phenyl-[(2-thiophen-2-yl-quinoline-4-carbonyl)-amino]-acetic acid methyl ester


name: [(R)-1-Methyl-2-phenyl-1-((S)-1-phenyl-ethylcarbamoyl)-ethyl]-carbamic acid (R)-2-methyl-1-phenyl-propyl ester


name: [(2-Furan-2-yl-quinoline-4-carbonyl)-amino]-phenyl-acetic acid methyl ester


name: {(S)-1-[1-(8-Hydroxy-octylcarbamoyl)-2-phenyl-ethylcarbamoyl]-1-methyl-2-phenyl-ethyl}-carbamic acid tert-butyl ester


name: {(S)-1-[1-(8-Hydroxy-octylcarbamoyl)-1-methyl-2-phenyl-ethylcarbamoyl]-2-phenyl-ethyl}-carbamic acid tert-butyl ester


name: N-phenyl-N''-(2-phenyl-quinoline-4-carbonyl)-hydrazinecarboxylic acid methyl ester


name: {[2-(2-Fluoro-phenyl)-quinoline-4-carbonyl]-amino}-phenyl-acetic acid methyl ester


name: {(S)-1-[1-(8-Methoxy-octylcarbamoyl)-1-methyl-2-phenyl-ethylcarbamoyl]-2-phenyl-ethyl}-carbamic acid tert-butyl ester


A member of the class of quinazolines that is quinazoline which is substituted at positions 2 and 4 by 6-methylpyridin-2-yl and pyridin-4-ylnitrilo groups, respectively. It is an ALK5 and PKN3 kinase inhibitor.


pyripyropene A

A sesquiterpenoid that consists of (3S,4R,4aR,6S,6aS,12R,12aS,12bS)-4-(acetoxymethyl)-12-hydroxy-4,6a,12b-trimethyl-11-oxo-9-(pyridin-3-yl)-1,3,4,4a,5,6,6a,12,12a,12b-decahydro-2H,11H-benzo[f]pyrano[4,3-b]chromene-3,6-diol in which the hydrogens of the 3- and 6-hydroxy functions are substituted by acetyl groups.


name: Benzoic acid 4-{(S)-2-tert-butylcarbamoyl-2-[(S)-2-(butyl-methyl-amino)-4-methyl-pentanoylamino]-ethyl}-phenyl ester


name: Benzoic acid 4-{(S)-2-tert-butylcarbamoyl-2-[(S)-4-methyl-2-(3-methyl-butylamino)-pentanoylamino]-ethyl}-phenyl ester


name: Benzoic acid 4-{(S)-2-[(S)-2-(benzyl-methyl-amino)-4-methyl-pentanoylamino]-2-tert-butylcarbamoyl-ethyl}-phenyl ester


name: Benzoic acid 4-{(S)-2-tert-butylcarbamoyl-2-[(S)-2-(isobutyl-methyl-amino)-4-methyl-pentanoylamino]-ethyl}-phenyl ester


name: Benzoic acid 4-{(S)-2-tert-butoxycarbonyl-2-[(S)-4-methyl-2-(3-methyl-butylamino)-pentanoylamino]-ethyl}-phenyl ester


name: (R)-2-tert-Butoxycarbonylamino-3-cyclohexylmethylsulfanyl-propionic acid 4-methoxy-benzyl ester


name: [(R)-2-Cyclopentylmethylsulfanyl-1-(4-methoxy-benzylcarbamoyl)-ethyl]-carbamic acid tert-butyl ester


name: (R)-3-Cyclohexylmethylsulfanyl-2-isobutoxycarbonylamino-propionic acid 4-methoxy-benzyl ester


name: 4-(3-Chloro-phenyl)-2,6-dimethyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid mono-(3-p-tolyl-allyl) ester


name: (R)-3-Cyclohexylmethylsulfanyl-2-(cyclopentanecarbonyl-amino)-propionic acid 4-methoxy-benzyl ester


name: Benzoic acid 4-((S)-2-tert-butoxycarbonyl-2-{[1-(3-methyl-butyl)-piperidine-2-carbonyl]-amino}-ethyl)-phenyl ester


name: (R)-3-Cyclohexylmethylsulfanyl-2-(3-methyl-butyrylamino)-propionic acid 4-methoxy-benzyl ester


name: (R)-2-(Cyclohexanecarbonyl-amino)-3-cyclohexylmethylsulfanyl-propionic acid 4-methoxy-benzyl ester


name: Benzoic acid 4-[(S)-2-tert-butylcarbamoyl-2-((S)-4-methyl-2-piperidin-1-yl-pentanoylamino)-ethyl]-phenyl ester


name: Benzoic acid 4-((S)-2-tert-butoxycarbonyl-2-{[1-(3-methyl-butyl)-piperidine-4-carbonyl]-amino}-ethyl)-phenyl ester


name: Benzoic acid 4-{(S)-2-tert-butylcarbamoyl-2-[(S)-2-(sec-butyl-methyl-amino)-4-methyl-pentanoylamino]-ethyl}-phenyl ester


name: 4-Methyl-2-methylamino-pentanoic acid [4,4-bis-(4-fluoro-phenyl)-butyl]-amide hydrochloride


name: Benzoic acid 4-((S)-2-tert-butylcarbamoyl-2-{2-[methyl-(3-methyl-butyl)-amino]-acetylamino}-ethyl)-phenyl ester


name: Benzoic acid 4-{(S)-2-tert-butylcarbamoyl-2-[(S)-4-methyl-2-(methyl-phenethyl-amino)-pentanoylamino]-ethyl}-phenyl ester


name: (R)-3-Cyclohexylmethylsulfanyl-2-[(thiazole-4-carbonyl)-amino]-propionic acid 4-methoxy-benzyl ester


name: Benzoic acid 4-[(S)-2-tert-butylcarbamoyl-2-((S)-2-dimethylamino-4-methyl-pentanoylamino)-ethyl]-phenyl ester


name: Benzoic acid 4-[(S)-2-tert-butylcarbamoyl-2-((S)-4-methyl-2-methylamino-pentanoylamino)-ethyl]-phenyl ester


name: (R)-3-Cyclohexylmethylsulfanyl-2-[((R)-thiazolidine-4-carbonyl)-amino]-propionic acid 4-methoxy-benzyl ester


name: Benzoic acid 4-{(S)-2-tert-butylcarbamoyl-2-[(S)-2-(isopropyl-methyl-amino)-4-methyl-pentanoylamino]-ethyl}-phenyl ester


name: N-Type calcium channel inhibitor APJ-2929


name: Benzoic acid 4-[(S)-2-((S)-2-amino-4-methyl-pentanoylamino)-2-tert-butylcarbamoyl-ethyl]-phenyl ester


name: 4-(3-Chloro-phenyl)-2,6-dimethyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid mono-(3,3-diphenyl-allyl) ester


name: (R)-2-Amino-3-cyclohexylmethylsulfanyl-propionic acid 4-methoxy-benzyl ester


name: Benzoic acid 4-[(S)-2-tert-butylcarbamoyl-2-((S)-4-methyl-2-morpholin-4-yl-pentanoylamino)-ethyl]-phenyl ester


L-NIL

An L-lysine derivative that is L-lysine in which one of the hydrogens attached to N(6) is substituted by an acetimidoyl group


name: Pyrrolo[3,4-c]pyrazole-5(1H)-carboxylic acid, 3-[(2,2-dimethyl-1-oxopropyl)amino]-4,6-dihydro-6,6-dimethyl-, (1S)-2-(dimethylamino)-1-phenylethyl ester


name: Pyrrolo[3,4-c]pyrazole-5(1H)-carboxylic acid, 3-[(4-fluorobenzoyl)amino]-4,6-dihydro-6,6-dimethyl-, (1S)-2-(dimethylamino)-1-phenylethyl ester


glutathione

A tripeptide compound consisting of glutamic acid attached via its side chain to the N-terminus of cysteinylglycine.


ROTENONE

A member of the class of rotenones that consists of 1,2,12,12a-tetrahydrochromeno[3,4-b]furo[2,3-h]chromen-6(6aH)-one substituted at position 2 by a prop-1-en-2-yl group and at positions 8 and 9 by methoxy groups (the 2R,6aS,12aS-isomer). A non-systemic insecticide, it is the principal insecticidal constituent of derris (the dried rhizome and root of Derris elliptica).


An organic heterotricyclic compound resulting from the formal fusion of the 2-3 bond of 5-chloroindole with the 2-3 bond of cycloheptanecarboxamide (the S enantiomer). It is a potent, cell-permeable, metabolically stable and selective inhibitor of the deacetylase SIRT1.


(R)-selisistat

A 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide that has R configuration. It is the inactive enantiomer.


(S)-selisistat

A 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide that has S configuration It is the active enantiomer.


SURAMIN HEXASODIUM

An organic sodium salt that is the hexasodium salt of suramin. It is an FDA approved drug for African sleeping sickness and river blindness.


toxoflavin

A pyrimidotriazine that is 1,6-dimethyl-1,5,6,7-tetrahydropyrimido[5,4-e][1,2,4]triazine with oxo groups at positions 5 and 7.


name: Uridine 5 inverted exclamation marka-(trihydrogen diphosphate), 2-thio-, P inverted exclamation marka-|A-D-glucopyranosyl ester


name: 4-(4-Acryloylamino-2-methoxy-benzenesulfonyl)-piperazine-1-carboxylic acid tert-butyl ester


name: Pyridin-3-yl-carbamic acid 4-(benzothiazol-2-ylmethoxy)-2-(2-phenyl-bicyclo[2.2.1]hept-2-yl)-phenyl ester


name: {4-[(9-Fluoro-5,6-dihydro-4H-3-thia-1-aza-benzo[e]azulen-2-ylamino)-methyl]-cyclohexyl}-carbamic acid methyl ester


name: trans-6-Chloro-2-(3'-oxo-3'H-spiro[cyclohex-1,1'-isobenzofuran]-4-yl)-3H-benzoimidazole-5-carboxylic acid methyl ester


name: 4-[(9-Fluoro-5,6-dihydro-4H-3-thia-1-aza-benzo[e]azulen-2-ylamino)-methyl]-piperidine-1-carboxylic acid ethyl ester


name: trans-4-Chloro-2-(3'-oxo-3'H-spiro[cyclohex-1,1'-isobenzofuran]-4-yl)-1H-benzoimidazole-5-carboxylic acid methyl ester


name: Acetic acid 4-(4-phenylamino-quinazolin-2-ylamino)-cyclohexyl ester


name: trans-2-(3'-Oxo-3'H-spiro[cyclohex-1,1'-isobenzofuran]-4-yl)-1H-benzoimidazole-5-carboxylic acid methyl ester


name: [4-(4-Phenylamino-quinazolin-2-ylamino)-benzyl]-phosphonic acid diethyl ester


name: Carbonic acid ethyl ester (R)-3-hydroxycarbamoyl-2-(4-methoxy-benzenesulfonyl)-1,2,3,4-tetrahydro-isoquinolin-7-yl ester


name: [4-((R)-3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquinoline-2-sulfonyl)-phenyl]-carbamic acid ethyl ester


name: 5-((R)-3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquinoline-2-sulfonyl)-4-methoxy-thiophene-3-carboxylic acid methyl ester


name: [3-(3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquinoline-2-sulfonyl)-phenyl]-carbamic acid 4-methoxy-phenyl ester


name: [3-((R)-3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquinoline-2-sulfonyl)-phenyl]-carbamic acid 4-methoxy-phenyl ester


name: [3-(3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquinoline-2-sulfonyl)-phenyl]-carbamic acid ethyl ester


name: Indan-2,2-dicarboxylic acid hydroxyamide (3-phenyl-propyl)-amide


name: [3-((R)-3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquinoline-2-sulfonyl)-phenyl]-carbamic acid ethyl ester


name: [4-((R)-3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquinoline-2-sulfonyl)-phenyl]-carbamic acid benzyl ester


name: 2-Mercapto-4-(4-methoxy-benzenesulfonyl)-butyric acid methyl ester


name: [(S)-1-Hydroxycarbamoyl-2-(4-phenoxy-benzenesulfonyl)-ethyl]-carbamic acid tert-butyl ester


name: [(S)-1-Hydroxycarbamoyl-2-(4-phenoxy-benzenesulfonyl)-ethyl]-methyl-carbamic acid tert-butyl ester


name: [(S)-1-Hydroxycarbamoyl-2-(4-phenylsulfanyl-benzenesulfonyl)-ethyl]-carbamic acid benzyl ester


name: {[1-Hydroxycarbamoyl-2-(4-phenylsulfanyl-benzenesulfonyl)-ethylcarbamoyl]-methyl}-carbamic acid benzyl ester


name: 4-(4-Benzoylamino-naphthalene-1-sulfonylamino)-piperidine-1-carboxylic acid ethyl ester


name: 4-(4-o-Tolylcarbamoyl-naphthalene-1-sulfonylamino)-piperidine-1-carboxylic acid ethyl ester


name: 4-(4-Cyclohexylcarbamoyl-naphthalene-1-sulfonylamino)-piperidine-1-carboxylic acid ethyl ester


name: 4-(4-Benzoylamino-naphthalene-1-sulfonylamino)-piperidine-1-carboxylic acid tert-butyl ester


name: 4-{4-[(3-Phenyl-propylamino)-methyl]-naphthalene-1-sulfonylamino}-piperidine-1-carboxylic acid ethyl ester


name: 4-[4-(Phenethylamino-methyl)-naphthalene-1-sulfonylamino]-piperidine-1-carboxylic acid ethyl ester


name: 4-[4-(Benzylamino-methyl)-naphthalene-1-sulfonylamino]piperidine-1-carboxylic acid ethyl ester


A member of the class of diamino-1,3,5-triazines that is 1,3,5-triazine-2,4-diamine in which the amino groups at positions 2 and 4 are respectively carrying 2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl and 2-(propan-2-ylsulfonyl)phenyl substituents. It is a potent inhibitor of anaplastic lymphoma kinase (ALK), Ack and ROS1 activity (IC50 values are 3.5, 5.8 and 8.9 nM respectively) and exhibits anti-cancer properties.


Phe-Gly

A dipeptide formed from L-phenylalanine and glycine residues.


name: 3-Piperidinecarboxylic acid, 1-((2R)-2-((2-amino-2-methyl-1-oxopropyl)amino)-3-(1H-indol-3-yl)-1-oxopropyl)-3-(phenylmethyl)-, ethyl ester, (3S)-


name: Carbamic acid, N-(4-hydroxybutyl)-, 2-(5-((1S)-1-((2-amino-2-methyl-1-oxopropyl)amino)-2-(phenylmethoxy)ethyl)-1H-tetrazol-1-yl)ethyl ester


name: [2-(4-Diethylamino-phenylcarbamoyl)-1,2,3,4-tetrahydro-naphthalen-2-yl]-carbamic acid isobutyl ester


A 1,2,3,4-tetrahydroisoquinoline hacing chloro substituents at the 7- and 8-positions.


name: 3-[4-(4-Benzyl-phenoxy)-butylamino]-propionic acid ethyl ester


name: [4-(4-Benzyl-phenoxy)-butylamino]-acetic acid ethyl ester


name: {2-[2-(4-Benzyl-phenoxy)-ethyl]-2-aza-bicyclo[2.2.1]hept-5-yl}-acetic acid methyl ester


name: 3-{Methyl-[3-(4-thiophen-2-ylmethyl-phenoxy)-propyl]-amino}-propionic acid methyl ester


name: 3-Amino-4-(4-benzyloxy-phenyl)-2-oxo-butyric acid benzyl ester


name: 2-[2-(4-Benzyl-phenoxy)-ethyl]-2-aza-bicyclo[2.2.1]heptane-5-carboxylic acid methyl ester


name: 3-[3-(4-Benzyl-phenoxy)-propylamino]-propionic acid ethyl ester


name: 3-{[3-(4-Benzyl-phenoxy)-propyl]-methyl-amino}-propionic acid ethyl ester


name: ({1-[2-(4-Benzyl-phenoxy)-ethyl]-piperidine-4-carbonyl}-amino)-acetic acid ethyl ester


name: 3-[2-(4-Benzyl-phenoxy)-ethylamino]-propionic acid methyl ester


name: 3-{Methyl-[3-(4-thiophen-3-ylmethyl-phenoxy)-propyl]-amino}-propionic acid methyl ester


name: [5-(4-Benzyl-phenoxy)-pentylamino]-acetic acid ethyl ester


name: 3-{Methyl-[3-(4-pyridin-3-ylmethyl-phenoxy)-propyl]-amino}-propionic acid methyl ester


name: {1-[2-(4-Benzyl-phenoxy)-ethyl]-pyrrolidin-3-yl}-acetic acid methyl ester


name: 4-{[2-(4-Benzyl-phenoxy)-ethyl]-methyl-amino}-butyric acid methyl ester


name: (S)-1-[2-(4-Benzyl-phenoxy)-ethyl]-pyrrolidine-2-carboxylic acid methyl ester


name: 3-{[4-(4-Benzyl-phenoxy)-butyl]-methyl-amino}-propionic acid ethyl ester


name: 3-Amino-4-(4-benzyloxy-phenyl)-2-oxo-butyric acid methyl ester


name: 3-Amino-4-(4-benzyloxy-phenyl)-2-hydroxy-butyric acid benzyl ester


A biaryl resulting from the formal oxidative coupling of the 6 position of 3-(piperidin-4-yl)-1,2-benzoxazole with the 3 position of p-toluic acid and subsequent condensation of the carboxy group with the primary amino group of 3-(morpholin-4-yl)aniline to give the corresponding carboxamide. An inhibitor of p38-alpha MAP kinase.


name: 6-Methyl-biphenyl-3,4''-dicarboxylic acid 3-cyclopropylamide 4''-[4-(4-methyl-piperazin-1-yl)-benzylamide]


A member of the class of benzamides obtained by formal condensation of the carboxy group of 3-{[1-(2,4-difluorophenyl)-7-methyl-6-oxo-6,7-dihydropyrazolo[3,4-b]pyridin-4-yl]amino}-4-methylbenzoic acid with the amino group of cyclopropylamine.


name: 6-Methyl-biphenyl-3,4''-dicarboxylic acid 3-cyclopropylamide 4''-(3-methoxy-benzylamide)


name: 6-Methyl-biphenyl-3,4''-dicarboxylic acid 4''-[(3-cyano-phenyl)-amide] 3-cyclopropylamide


name: 5-tert-Butyl-3-[3-(2,3-dichloro-phenyl)-ureido]-1H-pyrrole-2-carboxylic acid methyl ester


name: 3,5-Dichloro-4-[6-(4-fluoro-phenylsulfanyl)-2-oxo-3,4-dihydro-2H-pyrido[3,2-d]pyrimidin-1-yl]-benzoic acid methyl ester


A member of the class of biphenyls that is biphenyl in which one of the phenyl groups is substituted at positions 2and 4 by a methyl and a 5-methyl-1,3,4-oxadiazol-2-yl groups, respectively, while the other phenyl group is substituted at positions 2 and 5 by a methyl and an N-(cyclopropyl)aminocarbohyl group, respectively. An inhibitor of p38-alpha MAP kinase.


name: 5-tert-Butyl-3-(3-naphthalen-1-yl-ureido)-1H-pyrrole-2-carboxylic acid methyl ester


name: Carbamic acid 3,5-dichloro-4-[6-(4-fluoro-phenylsulfanyl)-2-oxo-3,4-dihydro-2H-pyrido[3,2-d]pyrimidin-1-yl]-phenyl ester


name: 5-tert-Butyl-3-[3-(3-chloro-phenyl)-ureido]-1H-pyrrole-2-carboxylic acid methyl ester


name: Acetic acid 1-(4-phenyl-piperidin-1-ylmethyl)-propyl ester


name: 3-[methyl-[(3E,7E)-4,8,12-trimethyltrideca-3,7,11-trienyl]amino]propyl phosphono hydrogen phosphate


name: [4-Chloro-3-(5-chloro-benzothiazol-2-yl)-phenyl]-carbamic acid prop-2-ynyl ester


name: [3-(5-Chloro-benzothiazol-2-yl)-4-methyl-phenyl]-carbamic acid prop-2-ynyl ester


name: (4-Chloro-3-(5-trifluoromethyl-benzothiazol-2-yl)-phenyl)-carbamic Acid Prop-2-ynyl Ester


name: (4-Chloro-3-(5-chloro-benzooxazol-2-yl)-phenyl)-carbamic Acid Prop-2-ynyl Ester


name: [4-Chloro-3-(5-chloro-benzothiazol-2-yl)-phenyl]-carbamic acid methyl ester


name: (3-Benzooxazol-2-yl-4-chloro-phenyl)-carbamic acid prop-2-ynyl ester


name: [4-Chloro-3-(5-chloro-1-methyl-1H-benzoimidazol-2-yl)-phenyl]-carbamic acid prop-2-ynyl ester


name: [4-Chloro-3-(5-chloro-benzooxazol-2-yl)-phenyl]-carbamic acid but-3-ynyl ester


name: [4-Chloro-3-(5-chloro-benzooxazol-2-yl)-phenyl]-carbamic acid but-2-ynyl ester


name: [3-(5-Chloro-benzooxazol-2-yl)-4-methyl-phenyl]-carbamic acid prop-2-ynyl ester


name: [4-Chloro-3-(1-methyl-5-trifluoromethyl-1H-benzoimidazol-2-yl)-phenyl]-carbamic acid prop-2-ynyl ester


name: [4-Chloro-3-(5-trifluoromethyl-benzooxazol-2-yl)-phenyl]-carbamic acid prop-2-ynyl ester


name: [4-Chloro-3-(4-methyl-benzooxazol-2-yl)-phenyl]-carbamic acid prop-2-ynyl ester


name: [4-Chloro-3-(5-methyl-benzooxazol-2-yl)-phenyl]-carbamic acid prop-2-ynyl ester


name: (4-Chloro-3-(5-trifluoromethyl-benzothiazol-2-yl)-phenyl)-carbamic Acid Methyl Ester


name: (4-Chloro-3-(5-chloro-benzooxazol-2-yl)-phenyl)-carbamic Acid Methyl Ester


name: [4-Chloro-3-(6-methyl-benzooxazol-2-yl)-phenyl]-carbamic acid methyl ester


name: (3-Benzooxazol-2-yl-4-chloro-phenyl)-carbamic acid methyl ester


name: [4-Chloro-3-(4-methyl-benzooxazol-2-yl)-phenyl]-carbamic acid methyl ester


name: [3-(5-Chloro-benzooxazol-2-yl)-4-methyl-phenyl]-carbamic acid methyl ester


name: [4-Chloro-3-(5-chloro-1-methyl-1H-benzoimidazol-2-yl)-phenyl]-carbamic acid methyl ester


name: [4-Chloro-3-(5-trifluoromethyl-benzooxazol-2-yl)-phenyl]-carbamic acid methyl ester


name: [4-Chloro-3-(5-methyl-benzooxazol-2-yl)-phenyl]-carbamic acid methyl ester


name: 4-(4-{3-[2-(4-Chloro-phenoxymethyl)-4-methyl-benzoimidazol-1-yl]-propyl}-piperidin-1-yl)-butyric acid ethyl ester


name: 4-[3-(3-{3-[4-(3-Hydroxy-phenyl)-piperazin-1-yl]-propyl}-ureido)-phenyl]-2,6-dimethyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid 3-ethyl ester 5-methyl ester


name: 2,6-Dimethyl-4-(3-{3-[3-(4-phenyl-piperazin-1-yl)-propyl]-ureido}-phenyl)-1,4-dihydro-pyridine-3,5-dicarboxylic acid 3-ethyl ester 5-methyl ester


name: 2,6-Dimethyl-4-(3-{3-[3-(4-phenyl-piperidin-1-yl)-propyl]-ureido}-phenyl)-1,4-dihydro-pyridine-3,5-dicarboxylic acid 3-ethyl ester 5-methyl ester


name: 2,6-Dimethyl-4-(3-{3-[3-(4-o-tolyl-piperazin-1-yl)-propyl]-ureido}-phenyl)-1,4-dihydro-pyridine-3,5-dicarboxylic acid 3-ethyl ester 5-methyl ester


BAFILOMYCIN A1

The most used of the bafilomycins, a family of toxic macrolide antibiotics derived from Streptomyces griseus.


name: 5-tert-Butyl-2-[(E)-2-(2,3-dihydro-benzo[1,4]dioxin-6-ylcarbamoyl)-vinyl]-benzoic acid ethyl ester


N-arachidonoylserotonin

An N-acylserotonin obtained by formal condensation of the carboxy group of arachidonic acid with the primary amino group of serotonin.


LINOLEOYLETHANOLAMIDE

An N-acylethanolamine 18:2 that is the ethanolamide of linoleic acid.


cannabigerol

A member of the class of resorcinols that is resorcinol which is substituted by a (2E)-3,7-dimethylocta-2,6-dien-1-yl group at position 2 and by a pentyl group at position 5. It is a natural product found in Cannabis sativa and Helichrysum species.


N-oleoylserotonin

An N-acylserotonin obtained by formal condensation of the carboxy group of oleoic acid with the primary amino group of serotonin.


name: 3-[5-Hydroxy-4-methoxy-2-(nonanoylamino-methyl)-phenyl]-acrylic acid methyl ester


name: Benzenepropanoic acid, 3,7-dimethylocta-2,6-dienyl ester


name: (7-Hydroxy-naphthalen-1-yl)-carbamic acid phenyl ester


name: 2-Amino-N-[1R-(2-phenyl ethyl)]propanamide boronic acid


name: N-[1R-(2-phenyl ethyl)]benzamide boronic acid


name: N-(2-phenyl ethyl)benzamide boronic acid


PAULLONE

An indolobenzazepine that is 5,6,7,12-tetrahydroindolo[3,2-d][1]benzazepine carrying an oxo substituent at position 6.


name: 3-[3-(4-Benzofuran-3-yl-2,5-dioxo-2,5-dihydro-1H-pyrrol-3-yl)-1-methyl-1H-indol-7-yl]propionic Acid Ethyl Ester


name: [4-(2-Hydroxy-5-oxo-tetrahydro-furan-3-ylcarbamoyl)-6-oxo-decahydro-pyrido[1,2-a]azepin-7-yl]-carbamic acid benzyl ester


name: 3-((S)-2-Benzyloxycarbonylamino-3-methyl-butyrylamino)-5-fluoro-4-oxo-pentanoic acid methyl ester


NAPHTHAZALIN

A naphthoquinone that is 1,4-naphthoquinone in which the hydrogens at positions 5 and 8 are replaced by hydroxy groups.


name: 6-Chloro-2-(2-methoxy-ethoxy)-quinoline-5-carboxylic acid (4,4-difluoro-cyclohexyl methyl)-amide


name: 6-Chloro-2-cyclopent-1-enyl-quinoline-5-carboxylic acid (4,4-difluoro-cyclo hexyl methyl)-amide


name: 6-Chloro-2-(2-hydroxy-ethylamino)-quinoline-5-carboxylic acid (4,4-difluoro-cyclohexyl methyl)-amide


name: 6-Chloro-2-(2-methoxy-ethylamino)-quinoline-5-carboxylic acid (4,4-difluoro-cyclohexyl methyl)-amide


name: 5-But-2-ynyloxy-pyrazine-2-carboxylic acid [3-((3R,4aS)-1-amino-3-methyl-4a-oxo-3,4,6,7,8,9-hexahydro-4a inverted question mark6-thia-2,5,9a-triaza-benzocyclohepten-3-yl)-4-fluoro-phenyl]-amide


name: 3-Chloro-5-cyano-pyridine-2-carboxylic acid [3-((3R,4aS)-1-amino-3-methyl-4a-oxo-3,4,6,7,8,9-hexahydro-4a inverted question mark6-thia-2,5,9a-triaza-benzocyclohepten-3-yl)-4-fluoro-phenyl]-amide


name: 5-Fluoro-3-methyl-pyridine-2-carboxylic acid [3-((3R,4aS)-1-amino-3-methyl-4a-oxo-3,4,6,7,8,9-hexahydro-4a inverted question mark6-thia-2,5,9a-triaza-benzocyclohepten-3-yl)-4-fluoro-phenyl]-amide


(+)-gallocatechin gallate

A gallate ester obtained by formal condensation of the carboxy group of gallic acid with the (3S)-hydroxy group of (+)-gallocatechin.


name: 4-{4-Bromo-2-[(naphthalene-1-carbonyl)-amino]-phenyl}-piperazine-1-carboxylic acid tert-butyl ester


name: 2-(3-(3-(benzylcarbamoyl)-4-fluorophenyl)-5-(cyclopropylmethyl)-4-(3-fluoro-4-sulfamoylbenzyl)-1H-pyrazol-1-yl)thiazole-4-carboxylic acid: MS (ES) 664.0 (M + H)+, LCMS RT = 1.052 min.


name: 2-(3-(3-phenoxyphenyl)-4-(4-sulfamoylbenzyl)-1H-pyrazol-1-yl)thiazole-4-carboxylic acid; MS (ES) 532.9(M + H)+ LCMS RT = 0.98 min.


name: 2-(3-(3-((3-methoxybenzyl)oxy)phenyl)-4-(4-sulfamoylbenzyl)-1H-pyrazol-1-yl)thiazole-4-carboxylic acid; MS (ES) 576.9 (M + H)+ LCMS RT = 1.02 min.


name: 2-(5-(cyclopropylmethyl)-3-(4-fluoro-3-((5-(trifluoromethyl)furan-2-yl)methoxy)phenyl)-4-(3-fluoro-4-sulfamoylbenzyl)-1H-pyrazol-1-yl)thiazole-4-carboxylic acid; MS (ES) 694.9 (M + H)+, LCMS RT = 1.20 min.


name: 2-(3-([1,1''''-biphenyl]-3-yl)-5-(2-cyclopropylethyl)-4-(4-sulfamoylbenzyl)-1H-pyrazol-1-yl)thiazole-4-carboxylic acid (M + H)+ = 585


CATECHIN GALLATE

A gallate ester obtained by formal condensation of the carboxy group of gallic acid with the (3S)-hydroxy group of (+)-catechin.


theaflavin

A biflavonoid that is 3,4,5-trihydroxybenzocyclohepten-6-one which is substituted at positions 1 and 8 by (2R,3R)-3,5,7-trihydroxy-3,4-dihydro-2H-chromen-2-yl groups. It is the main red pigment in black tea.


ATPGAMMAS

A nucleoside triphosphate analogue that is ATP in which one of the oxygens attached to 3-phosphate group is replaced by sulfur.


FLAVONOL

A monohydroxyflavone that is the 3-hydroxy derivative of flavone.


scutellarein

Flavone substituted with hydroxy groups at C-4', -5, -6 and -7.


HOMOERIODICTYOL

A trihydroxyflavanone that consists of 3'-methoxyflavanone in which the three hydroxy substituents are located at positions 4', 5, and 7.


ATHRAQUINONES A

A dihydroxyanthraquinone that is anthracene-9,10-dione in which the two hydroxy groups are located at positions 1 and 2.


PENTOSALEN

A member of the class of psoralens that is psoralen substituted by a prenyloxy group at position 8. Isolated from Angelica dahurica and Angelica koreana, it acts as a acetylcholinesterase inhibitor.


name: (2S,3S)-2-Amino-3-((3-(thiophen-3-yl)-1-tosyl-1H-indol-6-yl)methoxy)succinic acid trifluoroacetic acid


name: (2S,3S)-2-Amino-3-((1-tosyl-3-(4-(trifluoromethyl)phenyl)-1H-indol-6-yl)methoxy)succinic acid trifluoroacetic acid


GLAUCARUBINONE

A quassinoid with formula C25H34O10. It is a natural product isolated from several plant species and exhibits anti-cancer and anti-malarial properties.


name: 2-[Methyl(2,5-dioxo-3-methyl-3-pyrroline-1-yl)amino]-4-(trifluoromethyl)-5-pyrimidinecarboxylic acid ethyl ester


name: 3-Mercapto-6-methyl-4-(1-methylcarbamoyl-2-phenyl-ethylcarbamoyl)-heptanoic acid methyl ester


name: 4-[2-(1H-Indol-3-yl)-1-methylcarbamoyl-ethylcarbamoyl]-3-mercapto-6-methyl-heptanoic acid methyl ester


name: 4-(2-Benzyloxy-1-methylcarbamoyl-propylcarbamoyl)-3-mercapto-6-methyl-heptanoic acid methyl ester


name: 3-Mercapto-4-[2-(4-methoxy-phenyl)-1-methylcarbamoyl-ethylcarbamoyl]-6-methyl-heptanoic acid methyl ester


name: 3-Mercapto-4-[2-(4-methoxy-phenyl)-1-methylcarbamoyl-ethylcarbamoyl]-6-methyl-heptanoic acid tert-butyl ester


name: [(S)-3-((R)-2-Hydroxycarbamoylmethyl-decanoylamino)-2-oxo-azepan-1-yl]-acetic acid methyl ester


name: 4-(1-Carbamoyl-2-phenyl-ethylcarbamoyl)-3-mercapto-6-methyl-heptanoic acid methyl ester


name: 3-Acetylsulfanyl-4-[2-(1H-indol-3-yl)-1-methylcarbamoyl-ethylcarbamoyl]-6-methyl-heptanoic acid methyl ester


name: (2R,4R)-2-Hydroxycarbamoyl-1-(4-methoxy-benzenesulfonyl)-piperidine-4-carboxylic acid methyl ester


name: 2-Isobutyl-3-mercapto-pentanedioic acid 5-amide 1-{[2-(4-methoxy-phenyl)-1-methylcarbamoyl-ethyl]-amide}


name: 3-Acetylsulfanyl-4-[2-(4-methoxy-phenyl)-1-methylcarbamoyl-ethylcarbamoyl]-6-methyl-heptanoic acid methyl ester


name: 3-Mercapto-6-methyl-4-(2-oxo-azacyclotridec-3-ylcarbamoyl)-heptanoic acid isopropyl ester


name: (S)-2-[(R)-3-Mercapto-2-(2,2,2-trifluoro-acetylamino)-propionylamino]-3-phenyl-propionic acid methyl ester


name: [(S)-3-((R)-2-Hydroxycarbamoylmethyl-4-methyl-pentanoylamino)-2-oxo-azepan-1-yl]-acetic acid methyl ester


name: (S)-[4-(2-Ethoxy-ethoxy)-phenyl]-((R)-3-hydroxycarbamoyl-3,4-dihydro-1H-isoquinolin-2-yl)-phosphinic acid ethyl ester


name: (S)-((R)-3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquinolin-2-yl)-(4-methoxy-phenyl)-phosphinic acid 2-fluoro-ethyl ester


name: 3-Mercapto-4-[2-(4-methoxy-phenyl)-1-methylcarbamoyl-ethylcarbamoyl]-6-methyl-heptanoic acid benzyl ester


bexagliflozin

A C-glycosyl comprising of beta-D-glucose in which the anomeric hydroxy group is replaced by a 4-chloro-3-({4-[2-(cyclopropyloxy)ethoxy]phenyl}methyl)phenyl group. It is a sodium-glucose co-transporter 2 (SGLT2) inhibitor indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.


name: 2-[3-[(2-Amino-6-methylpyridin-3-yl)methyl]-4-methyl-1,3-thiazol-3-ium-5-yl]ethyl phosphono hydrogen phosphate


An azaspiro compound resulting from the formal fusion of position 3 of 6-chloro-oxindole with position 3 of (2R,3SS5S)-3-(3-chloro-2-fluorophenyl)-5-(2,2-dimethylpropyl)-N-[2-(morpholin-4-yl)ethyl]pyrrolidine-2-carboxamide. It is a potent inhibitor of the MDM2-p53 interaction.


name: p53 and MDM2 proteins-interaction-inhibitor chiral


HELENALIN

A sesquiterpene lactone that is 3,3a,4,4a,7a,8,9,9a-octahydroazuleno[6,5-b]furan-2,5-dione substituted by a hydroxy group at position 4, methyl groups at positions 4a and 8 and a methylidene group at position 3 (the 3aS,4S,4aR,7aR,8R,9aR stereoisomer).


AROMATICIN

A sesquiterpene lactone that is 3,3a,4,4a,7a,8,9,9a-octahydroazuleno[6,5-b]furan-2,5-dione substituted by methyl groups at positions 4a and 8 and a methylidene group at position 3. Isolated from the aerial parts of Inula hupehensis, it exhibits anti-inflammatory activity.


name: 1-Piperidinecarboxylic acid, 4-oxo-3,5-bis(phenyl-methylene)-, ethyl ester


name: (6S,7S)-7-hydroxycarbamoyl-6-(3-phenyl-pyrrolidine-1-carbonyl)-5-aza-spiro[2.5]octane-5-carboxylic acid methyl ester


name: 1-Bromo-6-propyl-2-naphthalenyl Ester N,N-Dimethylcarbamic Acid


name: Acetic acid 2-({6-[2-(3,4-dichloro-phenoxy)-acetylamino]-4-methyl-quinolin-2-yl}-methyl-amino)-ethyl ester


name: {[2,2-Diphenyl-5-(4-phenyl-piperidin-1-yl)-pentylcarbamoyl]-methyl}-carbamic acid benzyl ester


A carboxamide resulting from the formal condensation of the carboxy group of 5-(p-methoxyphenyl)-1,3,4-oxadiazole-2-carboxylic acid with the amino group of 3-phenoxyazetidine and in which the phenoxy group has been substituted at the para- position by a 2-oxa-6-azaspiro[3.3]heptan-6-ylmethyl group. It is a melanin concentrating hormone receptor 1 (MCHr1) antagonist.


PYRAZOFURIN

A C-glycosyl compound that is 4-hydroxy-1H-pyrazole-5-carboxamide in which the hydrogen at position 3 has been replaced by a beta-D-ribofuranosyl group.


ZERUMBONE

A sesquiterpenoid and cyclic ketone that is (1E,4E,8E)-alpha-humulene which is substituted by an oxo group at the carbon atom attached to two double bonds. It is obtained by steam distillation from a type of edible ginger, Zingiber zerumbet Smith,  grown particularly in southeast Asia.


An organic heterobicyclic compound that is (1S,5R)-2-thiabicyclo[3.1.0]hexane carrying oxo, oxo, amino, carboxy, and carboxy groups at positions 2, 2, 4S, 4S, and 6S, respectively. It is a potent agonist of group II metabotropic glutamate receptors mGluR2 mGluR3 (Ki = 149 nM and 92 nM, respectively) and exhibits antipsychotic and anxiolytic efficacy in animal models.


name: 2-Methyl-2-{3-[pyridin-3-ylmethyl-(2,2,2-trifluoro-ethanesulfonyl)-amino]-phenoxy}-propionic acid ethyl ester


name: 3-[4-(6-Hydroxy-naphthalen-2-ylamino)-phenyl]-3-imidazol-1-yl-2,2-dimethyl-propionic acid methyl ester


(R)-talarozole

An N-{4-[2-ethyl-1-(1H-1,2,4-triazol-1-yl)butyl]phenyl}-1,3-benzothiazol-2-amine that is the (R)-enantiomer of talarozole. The racemate is used for the treatment of keratinization disorders, psoriasis and acne.


talarozole

A member of the class of benzothiazoles that is 2-amino-1,3-benzothiazole in which one of the amino hydrogens is replaced by a 4-[2-ethyl-1-(1H-1,2,4-triazol-1-yl)butyl]phenyl group.


name: 3-Imidazol-1-yl-3-[4-(6-methoxy-naphthalen-2-ylamino)-phenyl]-2,2-dimethyl-propionic acid methyl ester


name: 3-[4-(2-Ethoxy-naphthalen-1-ylamino)-phenyl]-3-imidazol-1-yl-2,2-dimethyl-propionic acid methyl ester


name: 8-Azabicyclo[3.2.1]octane-8-carboxylic acid, 3-[3-(1H-indazol-4-yl)-2-(4-pyridinyl)pyrazolo[1,5-a]pyrimidin-7-yl]-, ethyl ester


avutometinib

A member of the class of coumarins that is 4-methyl-7-[(pyrimidin-2-yl)oxy]coumarin carrying an additional [2-[(methylaminosulfonyl)amino]-3-fluoropyridin-4-yl]methyl substituent at position 3.


name: US8754233, 2-(5-Amino-3-methyl-1H-pyrazol-4-yl)-benzothiazole-6-sulfonic acid amide


name: US8754233, 2-(3-Amino-1H-pyrazol-4-yl)-5-fluoro-benzothiazole-6-sulfonic acid amide


name: 2-Aminobenzimidazole with trans-stilbene, 8x


eritoran

A lipid A derivative used for the treatment of severe sepsis.


name: 6-(4-Chloro-2-fluoro-phenylsulfamoyl)-cyclohex-1-enecarboxylic acid ethyl ester


PSORALEN

The simplest member of the class of psoralens that is 7H-furo[3,2-g]chromene having a keto group at position 7. It has been found in plants like  Psoralea corylifolia and Ficus salicifolia.


A member of the class of benzaldehydes that is benzaldehyde carrying a dimethylamino substituent at position 4. Used as an indicator for detection of indoles and hydrazine.


MENTHOFURAN

A monoterpenoid that is 4,5,6,7-tetrahydro-1-benzofuran substituted by methyl groups at positions 3 and 6.


A member of the class of quinolines that is quinoline substituted by a 6-[4-(piperazin-1-yl)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl group at position 5. It is a potent ALK inhibitor (IC50 values of 2.4, 1.3, 85.8, 2,133 and 9,276 nM for ALK1, ALK2, ALK3, ALK4 and ALK5, respectively).


A pyrazolopyrimidine that is pyrazolo[1,5-a]pyrimidine bearing quinolin-4-yl and 4-isopropyloxyphenyl substituents at positions 3 and 6 respectively.


A secondary carboxamide resulting from the formal condensation of the carboxy group of 4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)benzoic acid with the primary amino group of N(3)-[(4-methoxy-1H-pyrrolo[2,3-b]pyridin-5-yl)methyl]-4-methylbenzene-1,3-diamine. It is a potent inhibitor of discoidin domain receptor tyrosine kinase 1 and 2 (DDR1/2) with IC50 = 47 nM and 145 nM, respectively.