An aromatic ketone that is propiophenone in which the hydrogen alpha- to the keto group has been replaced by a methylamino group.


name: 3-(4-Chloro-phenyl)-8-thia-bicyclo[3.2.1]oct-2-ene-2-carboxylic acid methyl ester


name: (S)-3-[(4-Fluoro-phenyl)-phenyl-methoxy]-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester


name: (S)-3-[(4-Chloro-phenyl)-phenyl-methoxy]-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester


name: (R)-(3,4-Dichloro-phenyl)-(R)-tetrahydro-pyran-2-yl-acetic acid methyl ester


name: 3-(3,4-Dichloro-phenyl)-7-hydroxy-8-methyl-8-aza-bicyclo[3.2.1]oct-2-ene-2-carboxylic acid methyl ester


name: (S)-3-[Bis-(4-fluoro-phenyl)-methoxy]-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester


name: (S)-3-[(4-Bromo-phenyl)-phenyl-methoxy]-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester


name: (S)-(3,4-Dichloro-phenyl)-(S)-tetrahydro-pyran-2-yl-acetic acid methyl ester


name: 3-(4-Methylphenyl)tropane-2-carboxylic acid methyl ester


name: (S)-3-Benzhydryloxy-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester


name: (S)-8-Methyl-3-(phenyl-p-tolyl-methoxy)-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester


name: 3-(3,4-Dichloro-phenyl)-6-hydroxy-8-methyl-8-aza-bicyclo[3.2.1]oct-2-ene-2-carboxylic acid methyl ester


name: (S)-3-[(4-Iodo-phenyl)-phenyl-methoxy]-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester


name: 3-(4-Bromo-phenyl)-8-oxa-bicyclo[3.2.1]oct-2-ene-2-carboxylic acid methyl ester


name: 3-(4-Iodo-phenyl)-8-oxa-bicyclo[3.2.1]oct-2-ene-2-carboxylic acid methyl ester


name: (S)-3-[Bis-(4-bromo-phenyl)-methoxy]-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester


name: (S)-3-[Bis-(4-chloro-phenyl)-methoxy]-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester


name: 3-(4-Fluoro-phenyl)-7-hydroxy-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester


name: Cyclohexyl-(3,4-dichloro-phenyl)-acetic acid methyl ester


name: 4-(2-pyrrolidin-1-yl-pentanoyl)benzoic acid methyl Ester


name: (R)-(3,4-Dichloro-phenyl)-(S)-tetrahydro-pyran-2-yl-acetic acid methyl ester


name: 3-(4-Fluoro-phenyl)-8-thia-bicyclo[3.2.1]oct-2-ene-2-carboxylic acid methyl ester


name: (S)-8-Benzyl-3-[bis-(4-fluoro-phenyl)-methoxy]-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester


name: 7-Hydroxy-8-methyl-3-phenyl-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester


name: (S)-3-Di-p-tolylmethoxy-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester


name: 3-(4-Chloro-phenyl)-8-oxa-bicyclo[3.2.1]oct-2-ene-2-carboxylic acid methyl ester


name: 3-(4-Fluoro-phenyl)-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester


name: (S)-3-[(4-Bromo-phenyl)-(4-iodo-phenyl)-methoxy]-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester


name: 3-(4-Fluoro-phenyl)-bicyclo[3.2.1]oct-2-ene-2-carboxylic acid methyl ester


name: 3-(4-Fluoro-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]oct-2-ene-2-carboxylic acid methyl ester


pemoline

A member of the class of 1,3-oxazoles that is 1,3-oxazol-4(5H)-one which is substituted by an amino group at position 2 and by a phenyl group at position 5. A central nervous system stimulant, it was used to treat hyperactivity disorders in children, but withdrawn from use following reports of serious hepatotoxicity.


name: (S)-Naphthalen-2-yl-(S)-tetrahydro-pyran-2-yl-acetic acid methyl ester


name: 3-[Bis-(4-fluoro-phenyl)-methoxy]-6-hydroxy-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester


name: 3-(4-Fluoro-phenyl)-6-hydroxy-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester


name: (2R,3R)-3-[Bis-(4-fluoro-phenyl)-methoxy]-8-oxa-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester


name: 3-(4-Fluoro-phenyl)-8-oxa-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester


name: (S)-(3,4-Dichloro-phenyl)-(R)-tetrahydro-pyran-2-yl-acetic acid methyl ester


name: {1-[4,4-Bis-(4-fluoro-phenyl)-butyl]-piperidin-4-yl}-carbamic acid 2-(4-cyano-phenyl)-ethyl ester


name: 3-Phenyl-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester


name: (S)-3-[Bis-(4-iodo-phenyl)-methoxy]-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester


name: (R)-(4-Methoxy-phenyl)-carbamic acid 2-(2-carbamimidoyl-benzo[b]thiophen-4-yloxy)-2-phenyl-ethyl ester


name: (2-Methylamino-methyl-phenyl)-carbamic acid 2-(2-carbamimidoylbenzo[b]thiophen-4-yloxy)-2-phenyl-ethyl ester


name: [2-(Piperazin-1-ylmethyl)-phenyl]-carbamic acid 2-(2-carbamimidoylbenzo[b]thiophen-4-yloxy)-2-phenyl-ethyl ester


name: (2-Carbamimidoylbenzo[b]thiophen-6-yloxy)thiophen-2-ylacetic Acid Ethyl Ester


name: [4-(2-Dimethylamino-ethoxy)-phenyl]-carbamic acid 2-(2-carbamimidoylbenzo[b]thiophen-4-yloxy)-2-phenyl-ethyl ester


name: (2-Aminomethyl-phenyl)-carbamic acid 2-(2-carbamimidoyl-benzo[b]thiophen-4-yloxy)-2-phenyl-ethyl ester


name: (2-Aminomethyl-phenyl)-carbamic acid 2-(2-carbamimidoyl-6-fluorobenzo[b]thiophen-4-yloxy)-2-phenyl-ethyl ester


name: (2-Fluoro-phenyl)-carbamic acid 2-(2-carbamimidoyl-benzo[b]thiophen-4-yloxy)-2-phenyl-ethyl ester


name: (4-Methoxy-phenyl)-carbamic acid 2-(2-carbamimidoyl-benzo[b]thiophen-4-yloxy)-2-phenyl-ethyl ester


name: (2,4-Difluoro-phenyl)-carbamic acid 2-(2-carbamimidoyl-benzo[b]thiophen-4-yloxy)-2-phenyl-ethyl ester


name: (2,6-Difluoro-phenyl)-carbamic acid 2-(2-carbamimidoyl-benzo[b]thiophen-4-yloxy)-2-phenyl-ethyl ester


name: (4-Fluoro-phenyl)-carbamic acid 2-(2-carbamimidoyl-benzo[b]thiophen-4-yloxy)-2-phenyl-ethyl ester


name: (2-Dimethylaminomethyl-phenyl)-carbamic acid 2-(2-carbamimidoylbenzo[b]thiophen-4-yloxy)-2-phenyl-ethyl ester


name: (3,5-Dimethyl-1H-pyrazol-4-yl)-carbamic acid 2-(2-carbamimidoylbenzo[b]thiophen-4-yloxy)-2-phenyl-ethyl ester


name: (2-Dimethylaminomethyl-phenyl)-carbamic acid 2-(2-carbamimidoyl-6-fluorobenzo[b]thiophen-4-yloxy)-2-phenyl-ethyl ester


name: (2,5-Dimethyl-2H-pyrazol-3-yl)-carbamic acid 2-(2-carbamimidoylbenzo[b]thiophen-4-yloxy)-2-phenyl-ethyl ester


name: (3,5-Dimethyl-isoxazol-4-yl)-carbamic acid 2-(2-carbamimidoyl-benzo[b]thiophen-4-yloxy)-2-phenyl-ethyl ester


name: Phenyl-carbamic acid 2-(2-carbamimidoyl-6-fluoro-benzo[b]thiophen-4-yloxy)-2-phenyl-ethyl ester


name: (3-Fluoro-phenyl)-carbamic acid 2-(2-carbamimidoyl-benzo[b]thiophen-4-yloxy)-2-phenyl-ethyl ester


name: 3-(2-Carbamimidoylbenzo[b]thiophen-6-yloxy)-3-(4-chlorophenyl)propionic Acid Methyl Ester


name: (S)-(4-Methoxy-phenyl)-carbamic acid 2-(2-carbamimidoyl-benzo[b]thiophen-4-yloxy)-2-phenyl-ethyl ester


name: 4-(2-Carbamimidoylbenzo[b]thiophen-6-yloxy)-4-(4-chlorophenyl)butyric Acid Methyl Ester


name: [2-(2-Carbamimidoyl-benzo[b]thiophen-4-yloxy)-2-phenyl-ethyl]-carbamic acid phenyl ester


name: (2-Carbamimidoylbenzo[b]thiophen-4-yloxy)phenylacetic Acid Methyl Ester


name: 4-[4-Hydroxy-4-(3-trifluoromethyl-phenyl)-piperidin-1-yl]-2,2-diphenyl-butyric acid methyl ester


name: 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-2,2-diphenyl-butyric acid methyl ester


name: 4-[4-(4-Chloro-3-trifluoromethyl-phenyl)-4-hydroxy-piperidin-1-yl]-2,2-diphenyl-butyric acid methyl ester


LOPERAMIDE HYDROCHLORIDE

A hydrochloride obtained by combining loperamide with one equivalent of hydrochloric acid. Used for treatment of diarrhoea resulting from gastroenteritis or inflammatory bowel disease.


name: 1-Piperazinecarboxylic acid, 4-((3,4-dichlorophenyl)acetyl)-3-(1-pyrrolidinylmethyl)-, methyl ester, (3R)-


arisugacin A

An organic heterotetracyclic compound that is 4a,12a-dihydroxy-4,4,6a,12b-tetramethyl-4a,6,6a,12,12a,12b-hexahydro-4H,11H-benzo[f]pyrano[4,3-b]chromene-1,11(5H)-dione substituted by 3,4-dimethoxyphenyl group at position 9 (the 4aR,6aR,12aS,12bS steroisomer). Isolated from the culture broth of Penicillium, it acts as a selective inhibitor of acetylcholinesterase.


lipoic acid

The (R)-enantiomer of lipoic acid. A vitamin-like, C8 thia fatty acid with anti-oxidant properties.


p-CRESOL

A cresol that consists of toluene substituted by a hydroxy group at position 4. It is a metabolite of aromatic amino acid metabolism produced by intestinal microflora in humans and animals.


M-XYLENE

A xylene carrying methyl groups at positions 1 and 3.


A mononitrotoluene carrying a nitro group at position 3.


memantine

A primary aliphatic amine that is the 3,5-dimethyl derivative of 1-aminoadamantane. A low to moderate affinity uncompetitive (open-channel); NMDA receptor antagonist which binds preferentially to the NMDA receptor-operated cation channels.


toluene

The simplest member of the class toluenes consisting of a benzene core which bears a single methyl substituent.


GLABRANIN

A dihydroxyflavanone that is pinocembrin substituted by a prenyl group at position 8.


name: Dimethyl-carbamic acid 1-amino-indan-4-yl ester hydrochloride


O-XYLENE

A xylene substituted by methyl groups at positions 1 and 2.


fisetin

A 7-hydroxyflavonol with additional hydroxy groups at positions 3, 3' and 4'.


rutoside

A rutinoside that is quercetin with the hydroxy group at position C-3 substituted with glucose and rhamnose sugar groups.


name: Dimethyl-carbamic acid 1-dimethylamino-indan-4-yl ester hydrochloride


huperzine A

A sesquiterpene alkaloid isolated from a club moss Huperzia serrata that has been shown to exhibit neuroprotective activity. It is also an effective inhibitor of acetylcholinesterase and has attracted interest as a therapeutic candidate for Alzheimer's disease.


name: (+)-Hexyl-carbamic acid 1-ethyl-3a-methyl-1,2,3,3a,8,8a-hexahydro-1-aza-cyclopenta[a]inden-5-yl ester


name: Pyrrolo[2,3-b]indol-5-ol, 1,2,3,3a,8,8a-hexahydro-1,3a,8-trimethyl-, 5-(N-phenylcarbamate), (3aS,8aR)-, (2R,3R)-2,3-dihydroxybutanedioate (1:1);Pyrrolo[2,3-b]indol-5-ol, 1,2,3,3a,8,8a-hexahydro-1,3a,8-trimethyl-, 5-(N-phenylcarbamate), (3aS,8aR)-, (2R,3R)-2,3-dihydroxybutanedioate (1:1)


arisugacin B

An organic heterotetracyclic compound that is 4a,12a-dihydroxy-4,4,6a,12b-tetramethyl-4a,6,6a,12,12a,12b-hexahydro-4H,11H-benzo[f]pyrano[4,3-b]chromene-1,11(5H)-dione substituted by a 4-methoxyphenyl group at position 9 (the 4aR,6aR,12aS,12bS steroisomer). Isolated from the culture broth of Penicillium, it acts as a selective inhibitor of acetylcholinesterase.


name: Ethyl-methyl-carbamic acid 1-amino-indan-4-yl ester hydrochloride


name: (+)-Heptyl-carbamic acid 1-ethyl-3a-methyl-1,2,3,3a,8,8a-hexahydro-1-aza-cyclopenta[a]inden-5-yl ester


p-toluidine

An aminotoluene in which the amino substituent is para to the methyl group.


name: Carbamic acid, (10-(4-morpholinyl)decyl)-, 1,2,3,3a,8,8a-hexahydro-1,3a,8-trimethylpyrrolo(2,3-b)indol-5-yl ester, (3aS-cis)-


P-XYLENE

A xylene with methyl groups at positions 1 and 4.


METACRESOL

A cresol with the methyl substituent at position 3. It is a minor urinary metabolite of toluene.


irinotecan

A member of the class of pyranoindolizinoquinolines that is the carbamate ester obtained by formal condensation of the carboxy group of [1,4'-bipiperidine]-1'-carboxylic acid with the phenolic hydroxy group of (4S)-4,11-diethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2- hydrochloride]quinoline-3,14-dione. Used (in the form of its hydrochloride salt trihydrate) in combination with fluorouracil and leucovorin, for the treatment of patients with metastatic adenocarcinoma of the pancreas after disease progression following gemcitabine-based therapy. It is converted via hydrolysis of the carbamate linkage to its active metabolite, SN-38, which is ~1000 times more active.


name: Dimethyl-carbamic acid 1-prop-2-ynylamino-indan-4-yl ester hydrochloride


name: Carbamic acid, (8-(4-morpholinyl)octyl)-, 1,2,3,3a,8,8a-hexahydro-1,3a,8-trimethylpyrrolo(2,3-b)indol-5-yl ester, (3aS-cis)-


A mononitrotoluene that consists of toluene bearing a nitro substituent at the 4-position.


name: 1,11-Di(2-Isoquinoliniumyl)Undecane With Dibromide Ions


name: Benzo[b][1,8]naphthyridine-3-carboxylic acid, 5-amino-1,4,6,7,8,9-hexahydro-2-methyl-4-phenyl-, ethyl ester


name: Butyl-carbamic acid 16-hydroxy-hexadecyl ester


name: Carbamic acid, hexyl-, 2-ethyl-2,3,4,5-tetrahydro-5-methyl-1,5-methano-1H-2-benzazepin-7-yl ester, (+-)-


name: Butyl-carbamic acid 8-butylcarbamoyloxy-octyl ester


name: Methyl-carbamic acid 4-methyl-3-[(Z)-phenethylimino]-1,2,3,4-tetrahydro-cyclopenta[b]indol-7-yl ester


name: Butyl-carbamic acid 10-butylcarbamoyloxy-decyl ester


name: Butyl-carbamic acid 12-butylcarbamoyloxy-dodecyl ester


name: Butyl-carbamic acid 14-butylcarbamoyloxy-tetradecyl ester


name: Butyl-carbamic acid 16-butylcarbamoyloxy-hexadecyl ester


name: Indeno(2,1-b)pyrrol-5-ol, 1,2,3,3a,8,8a-hexahydro-1-ethyl-3a-methyl-, methylcarbamate (ester), cis-(+-)-


EDROPHONIUM CHLORIDE

The chloride salt of edrophonium. A reversible inhibitor of cholinesterase with a rapid onset (30-60 seconds after injection) but a short duration of action (5-15 minutes), it is used in myasthenia gravis both diagnostically and to distinguish between under- or over-treatment with other anticholinesterases. It has also been used for the reversal of neuromuscular blockade in anaesthesia, and for the management of poisoning due to tetrodotoxin, a neuromuscular blocking toxin found in puffer fish and other marine animals.


name: Butyl-carbamic acid 10-hydroxy-decyl ester


name: Butyl-carbamic acid 14-hydroxy-tetradecyl ester


name: Methyl-carbamic acid 8-chloro-4-methyl-3-[(Z)-methylimino]-1,2,3,4-tetrahydro-cyclopenta[b]indol-7-yl ester


name: Methyl-carbamic acid 8-bromo-3-[(Z)-ethylimino]-4-propyl-1,2,3,4-tetrahydro-cyclopenta[b]indol-7-yl ester


name: Butyl-carbamic acid 5-butylcarbamoyloxy-pentyl ester


name: (4-Methoxy-phenyl)-methyl-carbamic acid 3-amino-indan-5-yl ester hydrochloride


name: Butyl-carbamic acid 12-hydroxy-dodecyl ester


name: Butyl-carbamic acid 8-hydroxy-octyl ester


name: Carbamic acid, butyl-, 1,2-ethanediyl ester


name: Dimethyl-carbamic acid 3-amino-indan-4-yl ester hydrochloride


name: (-)Hexyl-carbamic acid 1-propyl-1,2,3,3a,8,8a-hexahydro-1-aza-cyclopenta[a]inden-5-yl ester


name: Dimethyl-carbamic acid 3-methylamino-indan-4-yl ester hydrochloride


name: Hexyl-methyl-carbamic acid 3-amino-indan-5-yl ester hydrochloride


name: Methyl-phenyl-carbamic acid 3-prop-2-ynylamino-indan-5-yl ester hydrochloride


PROPOXUR

A carbamate ester that is phenyl methylcarbamate substituted at position 2 by a propan-2-yloxy group.


dichlorvos

An alkenyl phosphate that is the 2,2-dichloroethenyl ester of dimethyl phosphate.


name: Methyl-carbamic acid 6-chloro-4-methyl-3-[(Z)-methylimino]-1,2,3,4-tetrahydro-cyclopenta[b]indol-7-yl ester


name: Dimethyl-carbamic acid 3-amino-indan-5-yl ester hydrochloride


methoxsalen

A member of the class of psoralens that is 7H-furo[3,2-g]chromen-7-one in which the 9 position is substituted by a methoxy group. It is a constituent of the fruits of Ammi majus. Like other psoralens, trioxsalen causes photosensitization of the skin. It is administered topically or orally in conjunction with UV-A for phototherapy treatment of vitiligo and severe psoriasis.


name: (4-Methoxy-phenyl)-methyl-carbamic acid 3-prop-2-ynylamino-indan-5-yl ester hydrochloride


name: 3H-Imidazole-4-carboxylic acid, 3-methyl-5-[(pyridin-4-ylmethyl)amino]-, (4-tert-butylphenyl)amide


ZM 323881

A member of the class of quinazolines carrying 2-fluoro-4-methyl-5-hydroxyanilino and benzyloxy substituents at positions 4 and 7 respectively.


name: 4-(3-Hydroxy-4-methyl-phenylamino)-5-propyl-pyrrolo[2,1-f][1,2,4]triazine-6-carboxylic acid ethyl ester


CABOZANTINIB S-MALATE

A malate salt that is the mono-(S)-malate salt of cabozantinib. A multi-tyrosine kinase inhibitor, used for the treatment of progressive, metastatic, medullary thyroid cancer.


A pyrazolopyrimidine that is pyrazolo[1,5-a]pyrimidine substituted by phenyl and 4-[2-(morpholin-4-yl)ethoxy]phenyl groups at positions 3 and 6, respectively. It is an inhibitor of VEGFR-2 (IC50 = 0.16 muM).


name: 4-(3-Hydroxy-4-methyl-phenylamino)-5-methyl-pyrrolo[2,1-f][1,2,4]triazine-6-carboxylic acid methyl ester


name: 4-(2,4-Difluoro-5-methoxycarbamoyl-phenylamino)-5-isopropyl-pyrrolo[2,1-f][1,2,4]triazine-6-carboxylic acid ethyl ester


name: 4-(3-Hydroxy-4-methyl-phenylamino)-5-isopropyl-pyrrolo[2,1-f][1,2,4]triazine-6-carboxylic acid ethyl ester


vatalanib succinate

A succinate salt obtained by combining vatalanib with one molar equivalent of succinic acid. It is a multi-targeted tyrosine kinase inhibitor for all isoforms of VEGFR, PDGFR and c-Kit.


name: 7-Amino-6-[4-(3-m-tolylureido)phenyl]pyrazolo[1,5-a]pyrimidine-3-carboxylic Acid Ethyl Ester


name: Phosphoric acid diethyl ester 4-isopropyl-6-methoxy-1,1,3-trioxo-1,3-dihydro-1lambda*6*-benzo[d]isothiazol-2-ylmethyl ester


name: (4S,6R)-6-Allyl-4-(naphthalene-2-sulfonyl)-5-oxo-hexahydro-pyrrolo[3,2-b]pyrrole-1-carboxylic acid benzyl ester


name: 1,4-Benzenediacetic acid, alpha,alpha,alpha',alpha'-tetramethyl-, bis(4-((2-carboxy-2-methylpropyl)sulfonyl)phenyl) ester


name: Phosphoric acid dibutyl ester 1,1,3-trioxo-1,3-dihydro-1lambda*6*-benzo[d]isothiazol-2-ylmethyl ester


name: Carbonic acid methyl ester 1-oxo-3-phenyl-2-[(3,3,3-trifluoro-1-isopropyl-2-oxo-propylcarbamoyl)-methyl]-2,9-dihydro-1H-beta-carbolin-8-yl ester


name: 2,4-Bis-(2,2-dimethyl-propionyloxy)-benzoic acid 5-(2,2-dimethyl-propionyloxy)-4-oxo-4H-pyran-2-ylmethyl ester


name: (3aS,6R)-6-Allyl-4-hexyl-5-oxo-hexahydro-pyrrolo[3,2-b]pyrrole-1-carboxylic acid benzyl ester


name: (3aS,6R)-6-Allyl-4-ethylcarbamoyl-5-oxo-hexahydro-pyrrolo[3,2-b]pyrrole-1-carboxylic acid benzyl ester


name: Benzoic acid 1,1,3-trioxo-1,3-dihydro-1lambda*6*-benzo[d]isothiazol-2-ylmethyl ester


name: (3R,6aS)-3-Allyl-2-oxo-hexahydro-furo[3,2-b]pyrrole-4-carboxylic acid benzyl ester


name: 3-Acetoxymethyl-7-fluoro-5,5,8-trioxo-5lambda*6*-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid tert-butyl ester


name: 3-Acetoxymethyl-7-methoxy-5,5,8-trioxo-5lambda*6*-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzyl ester


name: (3R,6aS)-3-Allyl-2-oxo-hexahydro-furo[3,2-b]pyrrole-4-carboxylic acid ethyl ester


name: Octadecanoic acid 5-isobutyryloxy-4-oxo-4H-pyran-2-ylmethyl ester


name: (3S,6aS)-3-Allyl-2-oxo-hexahydro-furo[3,2-b]pyrrole-4-carboxylic acid benzyl ester


name: 2,2-Dimethyl-propionic acid 2-benzoyl-5-(2,2-dimethyl-propionyloxy)-phenyl ester


name: 2,2-Dimethyl-propionic acid 4-[4-(2,2-dimethyl-propionyloxy)-benzenesulfonyl]-phenyl ester


name: (3aS,6R)-6-Allyl-4-(naphthalene-1-sulfonyl)-5-oxo-hexahydro-pyrrolo[3,2-b]pyrrole-1-carboxylic acid benzyl ester


name: (3aS,6R)-6-Allyl-4-formyl-5-oxo-hexahydro-pyrrolo[3,2-b]pyrrole-1-carboxylic acid benzyl ester


name: Octadecanoic acid 5-(2,2-dimethyl-propionyloxy)-4-oxo-4H-pyran-2-ylmethyl ester


name: 3,4,5-Tris-(2,2-dimethyl-propionyloxy)-benzoic acid 5-(2,2-dimethyl-propionyloxy)-4-oxo-4H-pyran-2-ylmethyl ester


A member of the class of isocoumarins that is isocoumarin substituted by chloro groups at positions 3 and 4. It is a serine protease inhibitor.


name: 3-Acetoxymethyl-7-methyl-5,5,8-trioxo-5lambda*6*-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid tert-butyl ester


name: Hexadecanoic acid 5-(2,2-dimethyl-propionyloxy)-4-oxo-4H-pyran-2-ylmethyl ester


name: 2,2-Dimethyl-propionic acid 4-[4-(2,2-dimethyl-propionyloxy)-phenylazo]-phenyl ester


name: Icosanoic acid 5-(2,2-dimethyl-propionyloxy)-4-oxo-4H-pyran-2-ylmethyl ester


name: Hexadec-9-enoic acid 5-(2,2-dimethyl-propionyloxy)-4-oxo-4H-pyran-2-ylmethyl ester


name: 2,2-Dimethyl-propionic acid 2-{2-[2-(4-carboxymethoxy-phenoxy)-acetylamino]-3-methyl-butyryl}-benzooxazol-4-yl ester


name: Isobutyric acid 4-(4-isobutyryloxy-benzoyl)-phenyl ester


name: Carbonic acid 8-butoxycarbonyloxy-3-methyl-9,10-dioxo-6-propoxy-9,10-dihydro-anthracen-1-yl ester butyl ester


name: Docos-13-enoic acid 5-(2,2-dimethyl-propionyloxy)-4-oxo-4H-pyran-2-ylmethyl ester


name: 3-Acetoxymethyl-7-methoxy-5,5,8-trioxo-5lambda*6*-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid ethyl ester


name: 3-Acetoxymethyl-7-methoxy-5,5,8-trioxo-5lambda*6*-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid methyl ester


name: 4-(2,2-Dimethyl-propionyloxy)-benzoic acid 5-(2,2-dimethyl-propionyloxy)-4-oxo-4H-pyran-2-ylmethyl ester


name: Icos-11-enoic acid 5-(2,2-dimethyl-propionyloxy)-4-oxo-4H-pyran-2-ylmethyl ester


name: (5,6-Dimethyl-4-oxo-4H-thieno[2,3-d][1,3]oxazin-2-ylsulfanyl)-acetic acid methyl ester


name: (R)-6-Ethyl-7-oxo-3-phenyl-4-thia-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid benzyl ester


name: Octadec-9-enoic acid 5-(2,2-dimethyl-propionyloxy)-4-oxo-4H-pyran-2-ylmethyl ester


name: 2,2-Dimethyl-propionic acid 4-benzoyl-2-(1-methyl-allyl)-phenyl ester


name: 3-Chloromethyl-7-methoxy-5,5,8-trioxo-5lambda*6*-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid tert-butyl ester


name: Carbonic acid 8-butoxycarbonyloxy-7-hexyl-9,10-dioxo-9,10-dihydro-anthracen-1-yl ester butyl ester


name: 2,2-Dimethyl-propionic acid 4-[4-(2,2-dimethyl-propionyloxy)-phenoxy]-phenyl ester


name: 2,2-Dimethyl-propionic acid 2-(2-benzyloxycarbonylamino-3-methyl-butyryl)-benzooxazol-4-yl ester


name: 2,2-Dimethyl-propionic acid 4-[4-(2,2-dimethyl-propionyloxy)-benzyl]-phenyl ester


name: 3-Ethyl-7-methoxy-5,5,8-trioxo-5lambda*6*-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid 4-carboxy-benzyl ester


name: (R)-3-Benzyl-6-isopropyl-7-oxo-4-thia-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid benzyl ester


name: 2,2-Dimethyl-tetradecanoic acid 5-(2,2-dimethyl-propionyloxy)-4-oxo-4H-pyran-2-ylmethyl ester


name: 2,2-Dimethyl-pentanoic acid 4-[4-(2,2-dimethyl-pentanoyloxy)-benzoyl]-phenyl ester


name: Propanoic acid, 2,2-dimethyl-, 6-[(2-benzoxazolylthio)methyl]-4-oxo-4H-pyran-3-yl ester


name: 3-Acetoxymethyl-7-methoxy-5,5,8-trioxo-5lambda*6*-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid isopropyl ester


name: 2,2-Dimethyl-propionic acid 2-allyl-4-benzoyl-phenyl ester


name: 2,2-Dimethyl-propionic acid 4-benzoyl-2-(2-methyl-allyl)-phenyl ester


name: 3-Acetoxymethyl-7-methoxy-5,5,8-trioxo-5lambda*6*-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid tert-butyl ester


name: (R)-6-Isopropyl-7-oxo-3-phenyl-4-thia-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid benzyl ester


name: 7-Methoxy-3-methoxymethyl-5,5,8-trioxo-5lambda*6*-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid tert-butyl ester


name: 2,2-Dimethyl-malonic acid 4-benzoyl-phenyl ester methyl ester


name: 2,2-Dimethyl-propionic acid 4-oxo-6-trityloxymethyl-4H-pyran-3-yl ester


name: 3-Acetoxymethyl-5,5,8-trioxo-7-phenoxy-5lambda*6*-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid tert-butyl ester


name: 10-Methoxy-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-aza-chrysene-5-carboxylic acid ethyl ester


name: 3-(8-Methanesulfonylamino-1-methoxy-6H-benzo[c]chromen-6-yl)-benzoic acid ethyl ester


name: 4-(8-Methanesulfonylamino-1-methoxy-6H-benzo[c]chromen-6-yl)-benzoic acid ethyl ester


ethisterone

A 17beta-hydroxy steroid that is testosterone in which the 17beta hydrogen is replaced by an ethynyl group. Ethisterone was the first orally active progestin and is a metabolite of danazol.


HYDRAZINECARBOXAMIDE

A monocarboxylic acid amide that is urea where one of the amino groups has been replaced with hydrazine.


name: 3-[2-Acetyl-4-(3-trifluoromethyl-benzyloxy)-phenoxy]-2-methoxymethyl-propionic acid methyl ester


ISATIN

An indoledione that is the 2,3-diketo derivative of indole.


TRANYLCYPROMINE HYDROCHLORIDE

A hydrochloride obtained by combining (1R,2S)-tranylcypromine with one equivalent of hydrochloric acid.


MAACKIAIN

The (-)-enantiomer of maackiain.


CHALCONE

The trans-isomer of chalcone.


A member of the class of  chalcones that is trans-chalcone substituted by a hydroxy group at position 4'.


name: (E)-3-Chlorocinnamic acid 2-oxo-2,3-dihydro-benzofuran-5-yl ester


A member of the class of 1,3-thiazole bearing 2-cyclopentylidenehydrazino and 4-chlorophenyl substituents at positions 2 and 4 respectively.


menadione

A member of the class of 1,4-naphthoquinones that is 1,4-naphthoquinone which is substituted at position 2 by a methyl group. It is used as a nutritional supplement and for the treatment of hypoprothrombinemia.


piperine

A N-acylpiperidine that is piperidine substituted by a (1E,3E)-1-(1,3-benzodioxol-5-yl)-5-oxopenta-1,3-dien-5-yl group at the nitrogen atom. It is an alkaloid isolated from the plant Piper nigrum.


A member of the class of imidazoles carrying 4-hydroxycyclohexyl, 4-fluorophenyl and 2-methoxypyrimidin-4-yl substituents at positions 1, 4 and 5 respectively.


name: 4-(2-Chloro-6-methyl-phenylamino)-imidazo[1,5-a]quinoxaline-6-carboxylic acid methyl ester


name: (E)-3-{3-[(4-Benzo[1,3]dioxol-5-yl-benzyl)-isobutyryl-amino]-phenyl}-acrylic acid methyl ester


name: (E)-3-[3-(Cyclohexanecarbonyl-{4-[(E)-2-(2-fluoro-phenyl)-vinyl]-benzyl}-amino)-phenyl]-acrylic acid methyl ester


name: (E)-3-(3-{Isobutyryl-[4-((E)-styryl)-benzyl]-amino}-phenyl)-acrylic acid methyl ester


name: (E)-3-[3-({4-[(E)-2-(2-Fluoro-phenyl)-vinyl]-benzyl}-isobutyryl-amino)-phenyl]-acrylic acid methyl ester


name: (E)-3-[3-({4-[(E)-2-(3-Fluoro-phenyl)-vinyl]-benzyl}-isobutyryl-amino)-phenyl]-acrylic acid methyl ester


name: (E)-3-[3-(Cyclohexanecarbonyl-{4-[(E)-2-(3-fluoro-phenyl)-vinyl]-benzyl}-amino)-phenyl]-acrylic acid methyl ester


name: (E)-3-{3-[1-(4-Benzo[1,3]dioxol-5-yl-benzyl)-3-isopropyl-ureido]-phenyl}-acrylic acid methyl ester


iclaprim

An aminopyrimidine that is 5-methylpyrimidine-2,4-diamine in which one of the hydrogens of the methyl group has been replaced by a 2-cyclopropyl-7,8-dimethoxy-2H-chromen-5-yl group.


trimethoprim

An aminopyrimidine antibiotic whose structure consists of pyrimidine 2,4-diamine and 1,2,3-trimethoxybenzene moieties linked by a methylene bridge.


cycloguanil

A triazine in which a 1,6-dihydro-1,3,5-triazine ring is substituted at N-1 by a 4-chlorophenyl group, at C-2 and -4 by amino groups and at C-6 by gem-dimethyl groups. A dihydrofolate reductase inhibitor, it is a metabolite of the antimalarial drug proguanil.


name: 2,4-Diamino-5-methylpyrido(2,3-d)pyrimidine, 6-((3-chlorophenylthio)methyl), 0.9 hydrate


name: 2,4-Diamino-5-methylpyrido(2,3-d)pyrimidine, 6-((3,4-dimethoxyphenylthio)methyl), 0.9 hydrate


name: 2,4-Diamino-5-methylpyrido(2,3-d)pyrimidine, 6-((3-methoxyphenylthio)methyl), 0.9 hydrate


DIAVERIDINE

An aminopyrimidine in which the pyrimidine ring carries amino substituents at C-2 and C-4 and a 3,4-dimethoxybenzyl group at C-5. A folic acid antagonist, it is used as a synergist with sulfonamides against the parasitic Eimeria species.


name: 2,4-Diamino-5-methylpyrido(2,3-d)pyrimidine, 6-((3-methylphenylthio)methyl), 0.7 hydrate


A benzazepine that is 2,3,4,5-tetrahydro-3-benzazepine bearing a 3-methylphenyl substituent at position 1, an allyl substituent at position 3, a chloro substituent at position 6 and two hydroxy substituents at positions 7 and 8. High affinity, selective dopamine D1-like receptor agonist. Ki values are 3.2, 3.1, 186, 66, 335, 1167, 1251 and 1385 nM at recombinant D1, D5, D2, D3, D4, 5-HT2A, alpha1A and alpha1B receptors respectively. Stimulates adenylyl cyclase (EC50 = 65 nM) but not phosphoinositide hydrolysis. Induces extreme arousal and hyperlocomotion following subcutaneous administration in monkeys.


A benzazepine that is 2,3,4,5-tetrahydro-3-benzazepine bearing a phenyl substituent at position 1, an allyl substituent at position 3 and two hydroxy substituents at positions 7 and 8. Selective dopamine D1-like receptor partial agonist (IC50 values are 19.7 and 2425 nM for binding to D1-like and D2-like receptors respectively). Centrally active following systemic administration in vivo.


A hydrobromide salt prepared from N-methyl-6-chloro-1-(3-methylphenyl)-2,3,4,5-tetrahydro-3-benzazepine-7,8-diol and one equivalent of hydrogen bromide. Dopamine D1-like receptor partial agonist (Ki values are 1.18, 7.56, 920 and 399 nM for rat D1, D5, D2 and D3 receptors respectively). May act as an antagonist in vivo, producing anti-Parkinsonian effects and antagonising the behavioral effects of cocaine.


SCOULERINE

A berberine alkaloid isolated from  Corydalis saxicola.


(R)-SKF 38393 hydrobromide

A hydrobromide obtained by combining (R)-SKF 38393 with one molar equivalent of hydrogen bromide.


(S)-nandinine

A berberine alkaloid that is 5,8,13,13a-tetrahydro-2H,6H-[1,3]dioxolo[4,5-g]isoquinolino[3,2-a]isoquinoline carrying hydroxy and methoxy substituents at positions 9 and 10 respectively.


name: 2-{3-[2-(2-Carboxy-ethyl)-benzyl]-7-oxa-bicyclo[2.2.1]hept-2-yl}-oxazole-4-carboxylic acid 4-cyclohexyl-butyl ester


name: (Z)-7-[(1R,2S,3S,4S)-3-(Biphenyl-4-sulfonylamino)-bicyclo[2.2.1]hept-2-yl]-hept-5-enoic acid methyl ester


RU 58668

A 17beta-hydroxy steroid that is 17beta-estradiol in the the hydrogen at the 11beta position has been replaced by a p-({5-[(4,4,5,5,5-pentafluoropentyl)sulfonyl]pentyl}oxy)phenyl group. RU 58668 is a pure anti-estrogen that downregulates estrogen receptor expression (IC50 = 0.04 nM).


AFIMOXIFENE

A tertiary amino compound that is tamoxifen in which the phenyl group which is in a Z- relationship to the ethyl substituent is hydroxylated at the para- position. It is the active metabolite of tamoxifen.


name: (E)-3-(4-((2-(2-ethylphenyl)-6-hydroxybenzo[b] thiophen-3-yl)oxy) phenyl)-acrylic acid


name: (E)-3-(4-((2-(2-(tert-butyl)phenyl)-6-hydroxybenzo[b] thiophen-3-yl)oxy) phenyl)-acrylic acid


name: (E)-3-(4-((6-hydroxy-2-(2-(trifluoromethyl)-phenyl)benzo[b] thiophen-3-yl)oxy) phenyl)-acrylic acid


name: (E)-3-(4-((2-(4-fluoro-2-methylphenyl)-6-hydroxybenzo[b] thiophen-3-yl)oxy) phenyl)-acrylic acid


estradiol benzoate

A benzoate ester resulting from the formal condensation of benzoic acid with the phenolic hydroxy group of 17beta-estradiol.


name: 6-Hydroxy-1-[4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-3,4-dihydro-1H-isoquinoline-2-carboxylic acid ethyl ester


A 3-hydroxy steroid that is 17beta-estradiol substituted by a 11-[butyl(methyl)amino]-11-oxoundecyl group at position 7R. It is a steroidal antioestrogen that inhibits the cell proliferation of breast-carcinoma cell lines.


dehydrodiconiferyl alcohol

A guaiacyl lignin obtained by cyclodimerisation of coniferol.


name: Benzeneacetic acid, 2,3-bis((2-chlorophenyl)methoxy)-alpha-hydroxy-, (alphaS)-


8-anilinonaphthalene-1-sulfonic acid

A naphthalenesulfonic acid that is naphthalene-1-sulfonic acid substituted by a phenylamino group at position 8.


palmitic acid

A straight-chain, sixteen-carbon, saturated long-chain fatty acid.


A 7-hydroxyisoflavone that is daidzein  substituted by a hydroxy group at position 3'.


A hydroxyisoflavone that is isoflavone substituted by hydroxy groups at positions 3' and 4'. It has been isolated from Penicillium purpurogenum.


2-benzylsuccinic acid

A dicarboxylic acid consisting of succinic acid carrying a 2-benzyl substituent.


(R)-2-benzylsuccinic acid

The (R)-enantiomer of 2-benzylsuccinic acid.


A hydroxypiperidine that is duvoglustat in which the amino hydrogen is replaced by a methyl group. It is an inhibitor of alpha-glucosidase, an agonist of the glucose sensor SGLT3 and exhibits anti-HIV activity.


DESIPRAMINE HYDROCHLORIDE

The hydrochloride salt of desipramine.


name: 2,1,3-Benzothiadiazole-1(3H)-propanol, 3-(2-fluorophenyl)-alpha-[(methylamino)methyl]-, 2,2-dioxide, (alphaS)-


name: Biphenyl-2-ylmethyl-(S)-pyrrolidin-3-yl-carbamic acid methyl ester


name: 2-Hydroxyethyl [3-propoxy-2-(tridecanoylamino)propyl] hydrogen phosphate


DIADENOSINE TETRAPHOSPHATE

A diadenosyl tetraphosphate compound having the two 5'-adenosyl residues attached at the P(1)- and P(4)-positions.


zalcitabine

A pyrimidine 2',3'-dideoxyribonucleoside compound having cytosine as the nucleobase.


aminoguanidine

A one-carbon compound whose unique structure renders it capable of acting as a derivative of hydrazine, guanidine or formamide.


name: N4-Methoxycytidine 5''-Triphosphate triethylammonium Salt


A fluoroindole that is 6-fluoroindole in which the hydrogen at position 3 has been replaced by a 2-(pyridin-3-yl)vinyl group (trans configuration). It is a selective inhibitor of tryptophan 2,3-dioxygenase (TDO), which directs the conversion of trypophan to kynurenin.


name: 4-(4,9-Dioxo-4,9-dihydro-naphtho[2,3-d][1,2,3]triazol-1-yl)-benzoic acid methyl ester


name: N3-(4-(Trifluoro-methoxy) phenyl)furo [2,3-c] pyridine-2,3-diamine


name: Benzyl (3-((3-chloro-4-fluorophenyl) amino)furo [2,3-c]pyridin-2-yl)carbamate


name: 4-(2-Amino-3-((3-chloro-4-fluorophenyl) amino)furo [2,3-c]pyridin-7-yl) benzonitrile


name: Methyl 4-(2-amino-3-((3-chloro-4-fluorophenyl) amino)furo [2,3-c]pyridin-7-yl)benzoate


name: Benzyl (3-((3-chloro-4-fluorophenyl) amino)-7-cyanofuro [2,3-c]pyridin-2-yl)carbamate


name: 7-(Benzo[d] [1,3]dioxol-5-yl)-N3-(3-chloro-4-fluorophenyl) furo[2,3-c] pyridine-2,3-diamine


A pyrrolopyrimidine that is 7H-pyrrolo[2,3-d]pyrimidine substituted at position 4 by a methyl[(3R,4R)-4-methyl-1-(pyrrolidin-1-ylcarbonyl)piperidin-3-yl]nitrilo group. It is a potent JAK3-selective chemical probe.


N-nonyldeoxynojirimycin

A hydroxypiperidine that is deoxynojirimycin (duvoglustat) in which the amino hydrogen is replaced by a nonyl group.


A hydroxamic acid that is N-hydroxy-D-valinamide in which the alpha-amino group has been substituted by isopropoxy and [biphenyl]-4-ylsulfonyl groups. A selective matrix metalloproteinase-2 (MMP-2) inhibitor, it is one of the most potent inducers of autophagy. Its physiological roles include angiogenesis, cancer metastasis, embryogenesis, tissue remodeling in development, and wound healing.


CEFAMANDOLE SODIUM

An organic sodium salt that is the sodium salt of cefamandole.


PYRENE

An ortho- and peri-fused polycyclic arene consisting of four fused benzene rings, resulting in a flat aromatic system.


BETA-NAPHTHOFLAVONE

An extended flavonoid resulting from the formal fusion of a benzene ring with the f side of flavone.


bergapten

A 5-methoxyfurocoumarin that is psoralen substituted by a methoxy group at position 5.


diosmetin

A monomethoxyflavone that is the 4'-methyl ether derivative of luteolin. It is a natural product isolated from citrus fruits which exhibits a range of pharmacological activities.


CHRYSOERIOL

The 3'-O-methyl derivative of luteolin.


TAMARIXETIN

A monomethoxyflavone that is quercetin methylated at position O-4'. Isolated from Cyperus teneriffae.


A stilbenoid that is trans-resveratrol in which one of the meta-hydroxy groups is converted to the corresponding methyl ether.


EUPATORIN

A trimethoxyflavone that is 6-hydroxyluteolin in which the phenolic hydogens at positions 4', 6 and 7 have been replaced by methyl groups.


thapsigargin

An organic heterotricyclic compound that is a hexa-oxygenated 6,7-guaianolide isolated fron the roots of Thapsia garganica L., Apiaceae. A potent skin irritant, it is used in traditional medicine as a counter-irritant. Thapsigargin inhibits Ca(2+)-transporting ATPase mediated uptake of calcium ions into sarcoplasmic reticulum and is used in experimentation examining the impacts of increasing cytosolic calcium concentrations.


name: (7-Methyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinolin-9-ylmethyl)-carbamic acid benzyl ester


GLAUCINE

An  aporphine alkaloid that is (S)-1,2,9,10-tetrahydroxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline in which the four phenolic hydrogens have been replaced by methyl groups.


name: acetic acid 5-chloro-4-[2-methyl-4-(2-methyl-2H-pyrazol-3-yl)-quinolin-8-yloxymethyl]-pyridin-3-ylmethyl ester


An organoiodine compound consisting of uracil having an iodo substituent at the 5-position.


A 17-oxo steroid that is estrone in which the hydrogen at position 2 has been replaced by a methoxy group.


name: (R,R) Propane-2-sulfonic acid [2-(4-iodo-phenyl)-cyclopentyl]-amide


name: (+/-) Propane-2-sulfonic acid [2-(4-iodo-phenyl)-cyclopentyl]-amide


name: (+,-) Cis-propane-2-sulfonic Acid (2-p-bromophenyl-cyclopentyl)-amide


name: (+/-) Propane-2-sulfonic acid [2-(4-bromo-phenyl)-cyclopentyl]-amide


name: (R,R) Propane-2-sulfonic acid [2-(3,5-difluoro-phenyl)-cyclopentyl]-amide


name: (+,-) Cis-propane-2-sulfonic Acid (2-p-chlorophenyl-cyclopentyl)-amide


An alanine derivative that is L-alanine bearing a 5-fluorouracil-1-yl substituent at position 3. A more potent and selective AMPA receptor agonist (at hGluR1 and hGluR2) than AMPA itself (Ki = 14.7, 25.1, and 1820 nM for hGluR1, hGluR2 and hGluR5 respectively).


name: (R,R) Propane-2-sulfonic acid [2-(4-cyano-phenyl)-cyclopentyl]-amide


name: (+/-) Propane-2-sulfonic acid (2-p-tolyl-cyclopentyl)-amide


name: (+/-) Propane-2-sulfonic acid (2-phenyl-cyclopentyl)-amide


name: (+,-) Cis-Propane-2-sulfonic Acid [2-(3-fluoro-phenyl)-cyclopentyl]-amide


name: (+/-) Propane-2-sulfonic acid [2-(3,4-difluoro-phenyl)-cyclopentyl]-amide


(S)-ATPA

A non-proteinogenic L-alpha-amino acid that is L-alanine in which one of the methyl hydrogens is replaced by a 5-tert-butyl-3-hydroxy-isooxazol-4-yl group.


(S)-WILLARDIINE

The 3-(uracil-1-yl) derivative of L-alanine.


HINOKITIOL

A monoterpenoid that is cyclohepta-2,4,6-trien-1-one substituted by a hydroxy group at position 2 and an isopropyl group at position 4. Isolated from Thuja plicata and Chamaecyparis obtusa, it exhibits antimicrobial activities.


bithionol

An aryl sulfide that is diphenyl sulfide in which each phenyl group is substituted at position 2 by hydroxy and at positions 3 and 5 by chlorine. A fungicide and anthelmintic, it was used in various topical drug products for the treatment of liver flukes, but withdrawn after being shown to be a potent photosensitizer with the potential to cause serious skin disorders.


An organobromine compound that is dibenzodioxine carrying four bromo substituents at positions 2, 3, 7 and 8.


BENZO[DEF]CHRYSENE

An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.


POLYCHLORINATED BIPHENYL 126

A pentachlorobiphenyl in which the chlorines are located at the 3, 4, 5, 3', and 4' positions.


A pentacyclic ortho- and peri-fused polycyclic arene consisting of a dihydrocyclopenta[ij]tetraphene ring system with a methyl substituent at the 3-position.


A tetrachlorobiphenyl that is biphenyl in which the hydrogens at position 3 and 4 on each phenyl group are replaced by chlorines.


name: 2-[2-(Isothiazole-3-carbonyl)-pyrrolidine-1-carbonyl]-pyrrolidine-1-carboxylic acid benzyl ester


name: (R)-3-(Pyrrolidine-1-carbonyl)-2-aza-bicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester


name: (S)-2-[(S)-2-(5-Cyano-isoxazole-3-carbonyl)-pyrrolidine-1-carbonyl]-pyrrolidine-1-carboxylic acid benzyl ester


name: (R)-3-(2,5-Dihydro-pyrrole-1-carbonyl)-2-aza-bicyclo[2.2.2]octane-2-carboxylic acid tert-butyl ester


name: {6-Oxo-6-[(S)-3-(pyrrolidine-1-carbonyl)-3,4-dihydro-1H-isoquinolin-2-yl]-hexyl}-carbamic acid benzyl ester


name: (R)-3-(Pyrrolidine-1-carbonyl)-2-aza-bicyclo[2.2.2]octane-2-carboxylic acid tert-butyl ester


name: (R)-3-(Thiazolidine-3-carbonyl)-2-aza-bicyclo[2.2.2]octane-2-carboxylic acid tert-butyl ester


name: (3aS,7aS)-2-(Azetidine-1-carbonyl)-octahydro-indole-1-carboxylic acid tert-butyl ester


name: {5-Oxo-5-[(S)-3-(pyrrolidine-1-carbonyl)-3,4-dihydro-1H-isoquinolin-2-yl]-pentyl}-carbamic acid benzyl ester


name: {6-Oxo-6-[(S)-3-(pyrrolidine-1-carbonyl)-3,4-dihydro-1H-isoquinolin-2-yl]-hexyl}-carbamic acid tert-butyl ester


name: 2-(2-Dimethoxymethyl-pyrrolidine-1-carbonyl)-pyrrolidine-1-carboxylic acid benzyl ester


name: 2-(4-Dimethoxymethyl-thiazolidine-3-carbonyl)-pyrrolidine-1-carboxylic acid benzyl ester


name: 2-(2-[1,3]Dithiolan-2-yl-pyrrolidine-1-carbonyl)-pyrrolidine-1-carboxylic acid benzyl ester


name: 2-(2-[1,3]Dioxolan-2-yl-pyrrolidine-1-carbonyl)-pyrrolidine-1-carboxylic acid benzyl ester


name: (2E,4E)-5-(1H-Indol-2-yl)-2-methoxy-penta-2,4-dienoic acid methyl ester


(2S)-2-amino-4-phosphonobutanoic acid

A non-proteinogenc L-alpha-amino acid that is L-alpha-aminobutyric acid in which one of the hydrogens of the terminal methyl group has been replaced by a dihydroxy(oxido)-lambda(5)-phosphanyl group. It is a potent and selective agonist for the group III metabotropic glutamate receptors (mGluR4/6/7/8).


name: Phosphoric acid mono-[2-amino-4-(4-octyl-phenyl)-butyl] ester


name: Phosphoric acid mono-[1-amino-1-hydroxymethyl-3-(4-octyl-phenyl)-propyl] ester


A member of the class of isoquinolines that is the sulfonamide formed by the formal condensation of the sulfo group of 4-methylisoquinoline-5-sulfonic acid with the 1-amino group of (S)-2-methyl-1,4-diazepane.


name: N-(3-(ethylcarbamoyl) benzyl)-6H-isochromeno [3,4-c] pyridine-8-carboxamide


mupirocin

An alpha,beta-unsaturated ester resulting from the formal condensation of the alcoholic hydroxy group of 9-hydroxynonanoic acid with the carboxy group of (2E)-4-[(2S)-tetrahydro-2H-pyran-2-yl]-3-methylbut-2-enoic acid in which the tetrahydropyranyl ring is substituted at positions 3 and 4 by hydroxy groups and at position 5 by a {(2S,3S)-3-[(2S,3S)-3-hydroxybutan-2-yl]oxiran-2-yl}methyl group. Originally isolated from the Gram-negative bacterium Pseudomonas fluorescens, it is used as a topical antibiotic for the treatment of Gram-positive bacterial infections.


A member of the class of isoindoles that is  2,3-dihydro-1H-isoindole in which the hydrogens at positon 1 are replaced by an oxo group.


A member of the class of coumarins that is coumarin in which the hydrogen at position 3 is replaced by an acetyl group.


esculetin

A  hydroxycoumarin that is umbelliferone in which the hydrogen at position 6 is substituted by a hydroxy group. It is used in filters for absorption of ultraviolet light.


UMBELLIFERONE

A hydroxycoumarin that is coumarin substituted by a hydroxy group ay position 7.


SCOPOLIN

A member of the class of  coumarins that is scopoletin attached to a beta-D-glucopyranosyl residue at position 7 via a glycosidic linkage.


name: Benzoic acid 2-oxo-2H-chromen-7-yl ester


name: N-[7-(3-Methoxycarbonyl-propionylamino)-9,10-dioxo-9,10-dihydro-phenanthren-2-yl]-succinamic acid methyl ester


name: N-(9,10-Dioxo-9,10-dihydro-phenanthren-3-yl)-succinamic acid methyl ester


name: N-(9,10-Dioxo-9,10-dihydro-phenanthren-1-yl)-succinamic acid methyl ester


name: 7-(9,10-Dioxo-9,10-dihydro-phenanthren-2-ylcarbamoyl)-heptanoic acid methyl ester


name: [(9,10-Dioxo-9,10-dihydro-phenanthrene-3-carbonyl)-amino]-acetic acid tert-butyl ester


name: [(9,10-Dioxo-9,10-dihydro-phenanthrene-2-carbonyl)-amino]-acetic acid tert-butyl ester


name: 7-(9,10-Dioxo-9,10-dihydro-phenanthren-3-ylcarbamoyl)-heptanoic acid methyl ester


name: 4-(9,10-Dioxo-9,10-dihydro-phenanthren-3-ylcarbamoyl)-butyric acid methyl ester


name: Thiophosphoric acid (E)-dodec-9-enyl ester


name: Thiophosphoric acid (E)-tetradec-9-enyl ester


name: Phosphoric acid mono-((E)-dodec-9-enyl) ester


A 1,2-diacyl-sn-glycero-3-phosphate in which the acyl groups at positions 1 and 2 are specified as octanoyl.


name: Phosphoric acid mono-((E)-tetradec-11-enyl) ester


name: nonanoic acid (S)-2-nonanoyloxy-3-phosphonooxy-propyl ester


name: Phosphoric acid mono-((E)-tetradec-9-enyl) ester


LYSOPHOSPHATIDIC ACID

A 1-acyl-sn-glycerol 3-phosphate having oleoyl as the 1-O-acyl group.


ROCAGLAMIDE

An organic heterotricyclic compound that is 2,3,3a,8b-tetrahydro-1H-benzo[b]cyclopenta[d]furan substituted by hydroxy groups at positions 1 and 8b, methoxy groups at positions 6 and 8, a 4-methoxyphenyl group at position 3a, a phenyl group at position 3 and a N,N-dimethylcarbamoyl group at position 1. Isolated from Aglaia odorata and Aglaia duperreana, it exhibits antineoplastic activity.


name: 3-[(2-Chloro-4-trifluoromethyl-pyrimidine-5-carbonyl)-amino]-5-trifluoromethyl-benzoic acid butyl ester


GIBBERELLIN A3

A C19-gibberellin that is a pentacyclic diterpenoid responsible for promoting growth and elongation of cells in plants.  Initially identified in Gibberella fujikuroi,it differs from gibberellin A1 in the presence of a double bond between C-3 and C-4.


name: 3-[(2-Chloro-4-trifluoromethyl-pyrimidine-5-carbonyl)-amino]-5-trifluoromethyl-benzoic acid ethyl ester


name: 3-[(2-Chloro-4-trifluoromethyl-pyrimidine-5-carbonyl)-amino]-5-trifluoromethyl-benzoic acid hexyl ester


name: [3-(4-Guanidino-benzyl)-ureido]-acetic acid 5-{2-[3-(4-guanidino-benzyl)-ureido]-acetoxy}-cyclooctyl ester


name: Pentanedioic acid 4-aminomethyl-benzylamide 4-{[4-(4-aminomethyl-benzylcarbamoyl)-butyrylamino]-methyl}-benzylamide


name: Pentanedioic acid 4-guanidino-benzylamide 4-{[4-(4-guanidino-benzylcarbamoyl)-butyrylamino]-methyl}-benzylamide


name: 3-[4-(3,3-Diphenyl-propylcarbamoyl)-piperazin-1-yl]-2-(4-guanidino-phenyl)-3-oxo-propionic acid methyl ester


name: Piperazine-1,4-dicarboxylic acid 4-carbamimidoyl-benzylamide (3,3-diphenyl-propyl)-amide


name: Piperazine-1,4-dicarboxylic acid (3,3-diphenyl-propyl)-amide 4-guanidino-benzylamide


name: Piperazine-1,4-dicarboxylic acid (4,4-diphenyl-cyclohexyl)-amide 4-guanidino-benzylamide


BRYOSTATIN 1

A member of the class of bryostatins that is (17E)-2-oxooxacyclohexacos-17-ene which is substituted by hydroxy groups at positions 4, 10, and 20; an acetoxy group at position 8; methyl groups at positions 9, 9, 18, and 19; 2-methoxy-2-oxoethylidene groups at positions 14 and 24; an (E,E)-octa-2,4-dienoyloxy group at position 21; and with oxygen bridges linking positions 6 to 10, 12 to 16, and 20 to 24. It is one of the most abundant member of the class of bryostatins.


name: Nonanoic acid 2-hydroxy-1-(4-nonylidene-5-oxo-tetrahydro-furan-2-yl)-ethyl ester


name: Decanoic acid 2-hydroxymethyl-4-(3-isopropyl-4-methyl-pentylidene)-5-oxo-tetrahydro-furan-2-ylmethyl ester


name: Decanoic acid 2-hydroxymethyl-4-(3-methyl-butylidene)-5-oxo-tetrahydro-furan-2-ylmethyl ester


name: 3-Methyl-butyric acid 2-hydroxymethyl-4-(3-methyl-butylidene)-5-oxo-tetrahydro-furan-2-ylmethyl ester


name: 3-[2-Hydroxymethyl-4-(3-isopropyl-4-methyl-pentylidene)-5-oxo-tetrahydro-furan-2-yl]-acrylic acid hexyl ester


name: Hexanoic acid 2-hydroxymethyl-4-(3-isopropyl-4-methyl-pentylidene)-5-oxo-tetrahydro-furan-2-ylmethyl ester


name: Octanoic acid 2-hydroxymethyl-4-(3-isopropyl-4-methyl-pentylidene)-5-oxo-tetrahydro-furan-2-ylmethyl ester


name: Decanoic acid 2-hydroxymethyl-4-[3-isopropyl-4-methyl-pent-(Z)-ylidene]-5-oxo-tetrahydro-furan-2-ylmethyl ester


name: 3-Isopropyl-4-methyl-pentanoic acid 4-hexylidene-2-hydroxymethyl-5-oxo-tetrahydro-furan-2-ylmethyl ester


name: Benzoic acid 4-decylidene-2-hydroxymethyl-5-oxo-tetrahydro-furan-2-ylmethyl ester


INDOLACTUM

A 9-membered ring that is a potent protein kinase C activator


name: 3-(2-Hydroxymethyl-4-octadec-9-enylidene-5-oxo-tetrahydro-furan-2-yl)-acrylic acid methyl ester


name: 2,2-Dimethyl-propionic acid 2-hydroxymethyl-4-(3-isopropyl-4-methyl-pentylidene)-5-oxo-tetrahydro-furan-2-ylmethyl ester


name: Hexanoic acid 2-hydroxymethyl-4-(3-isopropyl-4-methyl-pent-2-enylidene)-5-oxo-tetrahydro-furan-2-ylmethyl ester


name: 3-Isopropyl-4-methyl-pentanoic acid 4-decylidene-2-hydroxymethyl-5-oxo-tetrahydro-furan-2-ylmethyl ester


name: 3-Methyl-butyric acid 4-decylidene-2-hydroxymethyl-5-oxo-tetrahydro-furan-2-ylmethyl ester


name: Benzoic acid 4-biphenyl-4-ylmethylene-2-hydroxymethyl-5-oxo-tetrahydro-furan-2-ylmethyl ester


name: 3-Isopropyl-4-methyl-pentanoic acid 3-hydroxymethyl-4-(3-methyl-butylidene)-5-oxo-tetrahydro-furan-2-ylmethyl ester


name: Biphenyl-4-carboxylic acid 4-decylidene-2-hydroxymethyl-5-oxo-tetrahydro-furan-2-ylmethyl ester


name: Butyric acid 2-hydroxymethyl-4-(3-isopropyl-4-methyl-pentylidene)-5-oxo-tetrahydro-furan-2-ylmethyl ester


name: 3-(4-Heptadec-9-enylidene-2-hydroxymethyl-5-oxo-tetrahydro-furan-2-yl)-acrylic acid methyl ester


debromoaplysiatoxin

A member of the class of aplysiatoxins that has the structure of the parent aplysiatoxin, but is lacking the bromo substituent on the benzene ring at the position para to the phenolic hydroxy group. It is a cyanotoxin produced by several species of freshwater and marine cyanobacteria, as well as algae and molluscs.


name: 4-(2-Carboxy-6-hydroxy-benzoyl)-3,5-dihydroxy-benzoic acid (S)-4-(4-hydroxy-benzoylamino)-pyrrolidin-3-yl ester


name: Biphenyl-4-carboxylic acid 4-biphenyl-4-ylmethylene-2-hydroxymethyl-5-oxo-tetrahydro-furan-2-ylmethyl ester


name: Acetic acid 2-hydroxymethyl-4-octadec-9-enylidene-5-oxo-tetrahydro-furan-2-ylmethyl ester


name: Acetic acid 4-((E)-heptadec-9-enylidene)-2-hydroxymethyl-5-oxo-tetrahydro-furan-2-ylmethyl ester


name: 3-Isopropyl-4-methyl-pentanoic acid 4-butylidene-2-hydroxymethyl-5-oxo-tetrahydro-furan-2-ylmethyl ester


name: Benzoic acid 2-hydroxymethyl-4-nonylidene-5-oxo-tetrahydro-furan-2-ylmethyl ester


name: Biphenyl-4-carboxylic acid 2-hydroxymethyl-4-nonylidene-5-oxo-tetrahydro-furan-2-ylmethyl ester


name: 3-Isopropyl-4-methyl-pentanoic acid 3-hydroxy-2-(3-isopropyl-4-methyl-pentanoyloxy)-propyl ester


name: 3-Isopropyl-4-methyl-pentanoic acid 3-hydroxymethyl-4-isopropylidene-5-oxo-tetrahydro-furan-2-ylmethyl ester


A member of the class of piperidinylimidazoles that is 1-methyl-4-(1-propylimidazol-2-yl)piperidine carrying additional 3,4-dichlorophenyl and 2-(cyclopropylamino)pyrimidin-4-yl substituents at positions 4 and 5 respectively.


An aminopyrimidine that is N-cyclohexyl-N-methylpyrimidin-2-amine in which the pyrimidine ring is substituted at position 4 by an imidazo[1,2-a]pyridin-3-yl group. It is an inhibitor of interleukin-1 receptor-associated kinase 4 (IRAK-4; EC 2.7.11.1).


A member of the class of  adenosines that is 5'-dehydro derivative of adenosine.


5'-CARBOXY ADENOSINE

A purine nucleoside having adenine as the nucleobase and a carboxy group at C-5'.


name: 4-(4-Acryloylamino-benzenesulfonyl)-piperazine-1-carboxylic acid 2-chloro-benzyl ester


name: 4-(4-Acryloylamino-benzenesulfonyl)-piperazine-1-carboxylic acid tert-butyl ester


name: 4-(4-Acryloylamino-benzenesulfonyl)-piperazine-1-carboxylic acid benzyl ester


name: 4-(4-Acryloylamino-2-trifluoromethyl-benzenesulfonyl)-piperazine-1-carboxylic acid benzyl ester


name: [1-(4-Acryloylamino-benzenesulfonyl)-piperidin-4-yl]-carbamic acid benzyl ester


name: [4-(4-Acryloylamino-piperidine-1-sulfonyl)-phenyl]carbamic acid benzyl ester


name: 4-(4-Acryloylamino-benzenesulfonylamino)-piperidine-1-carboxylic acid benzyl ester


DEOXYGUANOSINE TRIPHOSPHATE

A purine 2'-deoxyribonucleoside 5'-triphosphate having guanine as the nucleobase.


OLEIC ACID ANILIDE

The fatty amide resulting from the formal condensation of oleic acid and aniline.


BEAUVERIOLIDE I

A cyclodepsipeptide with formula C27H41N3O5. It was originally isolated from the fungus Beauveria sp. FO-6979 during a screening program for inhibitors of lipid droplet accumulation in murine macrophages. It is an inhibitor of acyl-CoA: cholesterol acyltransferase (ACAT) and effective at reducing atherogenic lesions of the artery and heart in mouse models.


name: 1-(2-chloro-phenyl)-5-[5-(3-methanesulfonyl-phenyl)thiophen-2-yl]-1H-pyrazole-3-carboxylic acid methyl ester


24(S), 25-epoxycholesterol

A 3beta-hydroxy-Delta(5)-steroid that is desmosterol in which the double bond at position 24-25 has been oxidised to the corresponding epoxide (the 24S diastereoisomer). It is an oxysterol agonist of the liver X receptor.


name: Phosphoric acid (S)-2-amino-5-guanidino-pentyl ester (2R,3S,4R,5R)-5-(6-amino-purin-9-yl)-3,4-dihydroxy-tetrahydro-furan-2-ylmethyl ester


name: rel-trans-[4-(Imidazo[4,5-d]pyrrolo[2,3-b]pyridin-1(6H)-yl)-cyclohexyl]-carbamic Acid tert-Butyl Ester


name: rel-cis-[4-(Imidazo[4,5-d]pyrrolo[2,3-b]pyridin-1(6H)-yl)-cyclohexyl]-carbamic acid tert-butyl ester


name: rel-trans-[4-(Imidazo[4,5-d]pyrrolo[2,3-b]pyridin-1(6H)-yl)-cyclohexyl]-carbamic acid methyl ester


RUXOLITINIB PHOSPHATE

A phosphate salt obtained by reaction ruxolitinib with one equivalent of phosphoric acid. Used for the treatment of patients with intermediate or high-risk myelofibrosis, including primary myelofibrosis, post-polycythemia vera myelofibrosis and post-essential thrombocythemia myelofibrosis.


name: rel-trans-N-Methyl-[4-(imidazo[4,5-d]pyrrolo[2,3-b]pyridin-1(6H)-yl)-cyclohexyl]-carbamic acid methyl ester


okadaic acid

A polycyclic ether that is produced by several species of dinoflagellates, and is known to accumulate in both marine sponges and shellfish.  A polyketide, polyether derivative of a C38 fatty acid, it is one of the primary causes of diarrhetic shellfish poisoning (DSP). It is a potent inhibitor of specific protein phosphatases and is known to have a variety of negative effects on cells.


cantharidin

A monoterpenoid with an epoxy-bridged cyclic dicarboxylic anhydride structure secreted by many species of blister beetle, and most notably by the Spanish fly, Lytta vesicatoria.  Natural toxin inhibitor of protein phosphatases 1 and 2A.


forskolin

A labdane diterpenoid isolated from the Indian Coleus plant.


name: 4-fluorobenzoic acid 4-[[5-(1-naphthalenyl)-1,3,4-oxadiazol-2-yl]thio]but-2-ynyl ester


name: 2-benzofurancarboxylic acid 4-[[5-(1-naphthalenyl)-1,3,4-oxadiazol-2-yl]thio]but-2-ynyl ester


name: 4-(dimethylamino)benzoic acid 4-[[5-(1-naphthalenyl)-1,3,4-oxadiazol-2-yl]thio]but-2-ynyl ester


name: 3,4,5-trifluorobenzoic acid 4-[[5-(1-naphthalenyl)-1,3,4-oxadiazol-2-yl]thio]but-2-ynyl ester


name: 2-naphthalenecarboxylic acid 4-[[5-(1-naphthalenyl)-1,3,4-oxadiazol-2-yl]thio]but-2-ynyl ester


name: 4-fluorobenzoic acid 4-[(5-phenyl-1,3,4-oxadiazol-2-yl)thio]but-2-ynyl ester


name: 3-(trifluoromethyl)benzoic acid 4-[[5-(1-naphthalenyl)-1,3,4-oxadiazol-2-yl]thio]but-2-ynyl ester


name: 4-methylsulfonylbenzoic acid 4-[[5-(1-naphthalenyl)-1,3,4-oxadiazol-2-yl]thio]but-2-ynyl ester


name: 4-fluorobenzoic acid 4-[[5-(2-fluorophenyl)-1,3,4-oxadiazol-2-yl]thio]but-2-ynyl ester


name: 4-fluorobenzoic acid 4-[[5-(2-chlorophenyl)-1,3,4-oxadiazol-2-yl]thio]but-2-ynyl ester


name: 1H-indole-4-carboxylic acid 4-[[5-(1-naphthalenyl)-1,3,4-oxadiazol-2-yl]thio]but-2-ynyl ester


name: 4-fluorobenzoic acid 4-[(5-thiophen-2-yl-1,3,4-oxadiazol-2-yl)thio]but-2-ynyl ester


name: 4-fluorobenzoic acid 4-[[5-(2-methoxyphenyl)-1,3,4-oxadiazol-2-yl]thio]but-2-ynyl ester


name: cyclobutanecarboxylic acid 4-[[5-(1-naphthalenyl)-1,3,4-oxadiazol-2-yl]thio]but-2-ynyl ester


name: 4-chloro-3-(trifluoromethyl)benzoic acid 4-[[5-(1-naphthalenyl)-1,3,4-oxadiazol-2-yl]thio]but-2-ynyl ester


name: 4-fluorobenzoic acid 4-[[5-(5-quinolinyl)-1,3,4-oxadiazol-2-yl]thio]but-2-ynyl ester


name: 6-{[3-(2-Chloro-4-fluorophenylcarbamoyl)pyrazole-1-carbonyl]-amino}-hexanoic acid ethyl ester


name: cyclopropanecarboxylic acid 4-[[5-(1-naphthalenyl)-1,3,4-oxadiazol-2-yl]thio]but-2-ynyl ester


name: 2-methoxybenzoic acid 4-[[5-(1-naphthalenyl)-1,3,4-oxadiazol-2-yl]thio]but-2-ynyl ester


name: 4-fluorobenzoic acid 4-[[5-(1-naphthalenyl)-1,3,4-oxadiazol-2-yl]thio]butyl ester


baicalein

A trihydroxyflavone with the hydroxy groups at positions C-5, -6 and -7.


An organic heterotetracyclic compound that is 1H-indole which is ortho-fused to a 2H-1-benzothiopyran group at positions 2-3. It is an inhibitor of 15-lipoxygenase that limits atherosclerotic lesion development in rabbits.


name: 1H-imidazole-5-carboxylic acid 4-[[5-(1-naphthalenyl)-1,3,4-oxadiazol-2-yl]thio]but-2-ynyl ester


name: 4-fluorobenzoic acid 4-[[5-(2-furanyl)-1,3,4-oxadiazol-2-yl]thio]but-2-ynyl ester


An organosulfonate salt that is the tetrakis(p-toluenesulfonate) salt of meso-tetrakis(N-methyl-4-pyridyl)porphine.


An aza-steroid that is 3-O-methyl-17beta-estradiol in which the 17beta-hydroxy group is replaced by a 6-(maleimid-1-yl)hexylamino group. An inibitor of phospholipase C.


An organic cation that is porphyrin bearing four 1-methylpyridinium-4-yl groups at the 5-, 10-, 15- and 20-positions.


celastrol

A pentacyclic triterpenoid that is 24,25,26-trinoroleana-1(10),3,5,7-tetraen-29-oic acid bearing an oxo substituent at position 2, a hydroxy substituent at position 3 and two methyl groups at positions 9 and 13. An antioxidant and anti-inflammatory agent. Potently inhibits lipid peroxidation in mitochondria and inhibits TNF-alpha-induced NFkappaB activation. Also shown to inhibit topoisomerase II activity in vitro (IC50 = 7.41 muM).


DIGITOXIGENIN

A 5beta-cardenolide that is 5beta-cardanolide with hydroxy substituents at the 3beta- and 14beta-positions and double bond unsaturation at C(20)-C(22).


name: 4-(2-Carboxy-6-hydroxy-benzoyl)-3,5-dihydroxy-benzoic acid (S)-2-(4-hydroxy-benzoylamino)-cyclopentyl ester


name: 2-[4-(Carboxy-difluoro-methyl)-benzyl]-2-[4-(difluoro-phosphono-methyl)-benzyl]-malonic acid dibenzyl ester


name: 2,2-Di{4-[difluoro(phosphono)methyl]benzyl}malonic acid, dibenzyl ester


name: Oxalyl-aryl-amino benzoic acid-based inhibitor 19


name: Oxalyl-aryl-amino benzoic acid-based inhibitor 17


name: 2,2-Bis-[4-(difluoro-phosphono-methyl)-benzyl]-malonic acid diisopropyl ester


name: Oxalyl-aryl-amino benzoic acid-based inhibitor 12


name: Oxalyl-aryl-amino benzoic acid-based inhibitor 18


name: 2,2-Bis-[4-(difluoro-phosphono-methyl)-benzyl]-malonic acid benzyl ester methyl ester


name: Oxalyl-aryl-amino benzoic acid-based inhibitor 15


name: 2-Benzotriazol-1-yl-3-[4-(difluoro-phosphono-methyl)-phenyl]-2-phenyl-propionic acid benzyl ester


name: Oxalyl-aryl-amino benzoic acid-based inhibitor 13


name: 3-(1-Indol-1-yl-3,4-dioxo-3,4-dihydro-naphthalen-2-yl)-propionic acid ethyl ester


name: 3-(5,6-Dioxo-8-phenyl-5,6-dihydro-naphthalen-2-yl)-propionic acid methyl ester


name: Oxalyl-aryl-amino benzoic acid-based inhibitor 20


name: 3-(3,4-Dioxo-1-phenyl-3,4-dihydro-naphthalen-2-yl)-propionic acid ethyl ester


name: Oxalyl-aryl-amino benzoic acid-based inhibitor 14


name: Oxalyl-aryl-amino benzoic acid-based inhibitor 8a


name: Oxalyl-aryl-amino benzoic acid-based inhibitor 21


name: [4-(1-Indol-1-yl-3,4-dioxo-3,4-dihydro-naphthalen-2-ylmethyl)-phenoxy]-acetic acid tert-butyl ester


name: (7,8-Dioxo-5-phenyl-7,8-dihydro-naphthalen-1-yl)-carbamic acid ethyl ester


name: 3-[7-(2-Methoxycarbonyl-ethyl)-3,4-dioxo-1-phenyl-3,4-dihydro-naphthalen-2-yl]-propionic acid methyl ester


name: Oxalyl-aryl-amino benzoic acid-based inhibitor 16


lobarin

A member of the class of 2-benzofurans that is 3-butyl-3-hydroxy-2-benzofuran-1(3H)-one substituted by a 3-carboxy-4,6-dihydroxy-2-pentylphenoxy group and a methoxy group at positions 4 and 6, respectively. It is a metabolite isolated from the Sumatran lichen, Stereocaulon halei.


name: 3-(8-Indol-1-yl-5,6-dioxo-5,6-dihydro-naphthalen-2-yl)-propionic acid methyl ester


name: 3-[1-Indol-1-yl-6-(2-methoxycarbonyl-ethyl)-3,4-dioxo-3,4-dihydro-naphthalen-2-yl]-propionic acid methyl ester


name: 2-[4-(Difluoro-phosphono-methyl)-benzyl]-2-(4-methanesulfonyl-benzyl)-malonic acid dibenzyl ester


name: 4-[2-(3,4-Dioxo-1-phenyl-3,4-dihydro-naphthalen-2-yl)-ethyl]-benzoic acid ethyl ester


name: [(2S,3R)-3-((S)-1-Carbamoyl-2-phenyl-ethylcarbamoyl)-2-hydroxycarbamoyl-5-methyl-hexylsulfanyl]-acetic acid methyl ester


batimastat

A secondary carboxamide resulting from the formal condensation of the carboxy group of (2S,3R)-5-methyl-3-{[(2S)-1-(methylamino)-1-oxo-3-phenylpropan-2-yl]carbamoyl}-2-[(thiophen-2-ylsulfanyl)methyl]hexanoic acid with the amino group of hydroxylamine. It a broad-spectrum matrix metalloprotease inhibitor.


name: Thioacetic acid S-[(2S,3R)-3-((S)-1-carbamoyl-2-phenyl-ethylcarbamoyl)-2-hydroxycarbamoyl-5-methyl-hexyl] ester


name: Acetic acid (2S,3S)-3-((S)-2-benzyloxycarbonylamino-4-methyl-pentanoylamino)-4-oxo-azetidin-2-yl ester


name: [(S)-1-((R)-1-Phenyl-ethylaminooxalyl)-pentyl]-carbamic acid adamantan-2-yl ester


name: [(S)-1-((R)-1-Phenyl-ethylaminooxalyl)-pentyl]-carbamic acid (S)-4,4-dimethyl-2-oxo-pyrrolidin-3-yl ester


name: Benzoic acid (2S,3S)-3-((S)-2-benzyloxycarbonylamino-3-phenyl-propionylamino)-4-oxo-azetidin-2-yl ester


name: 3-Phenyl-propionic acid (2S,3S)-3-((S)-2-benzyloxycarbonylamino-3-phenyl-propionylamino)-4-oxo-azetidin-2-yl ester


name: [(S)-1-((2S,3R)-2-Benzenesulfonyl-4-oxo-azetidin-3-ylcarbamoyl)-2-phenyl-ethyl]-carbamic acid benzyl ester


name: [(S)-1-((R)-1-Phenyl-ethylaminooxalyl)-pentyl]-carbamic acid (1S,3S,5R)-3,5-dimethyl-cyclohexyl ester


name: [(S)-1-((5S,6S)-7-Oxo-4-oxa-1-aza-bicyclo[3.2.0]hept-6-ylcarbamoyl)-2-phenyl-propyl]-carbamic acid benzyl ester


name: Acetic acid (1S,2S,4R)-3-[(2-benzyloxycarbonylamino-cyclohexanecarbonyl)-amino]-4-oxo-azetidin-2-yl ester


name: [(S)-1-((S)-3-Hydroxy-2-oxo-1-phenethyl-propylcarbamoyl)-3-methyl-butyl]-carbamic acid benzyl ester


name: Acetic acid (2S,3S)-3-((S)-2-benzyloxycarbonylamino-3-phenyl-propionylamino)-4-oxo-azetidin-2-yl ester


name: [(S)-2-Methyl-1-((5R,6S)-7-oxo-4-oxa-1-aza-bicyclo[3.2.0]hept-6-ylcarbamoyl)-propyl]-carbamic acid benzyl ester


name: [(S)-1-((3S,4S)-2-Oxo-4-phenoxy-azetidin-3-ylcarbamoyl)-2-phenyl-ethyl]-carbamic acid benzyl ester


name: [(S)-1-((3R,4S)-2-Oxo-4-phenylsulfanyl-azetidin-3-ylcarbamoyl)-2-phenyl-ethyl]-carbamic acid benzyl ester


name: [(S)-1-((2S,3S)-2-Butoxy-4-oxo-azetidin-3-ylcarbamoyl)-2-phenyl-ethyl]-carbamic acid benzyl ester


name: [(S)-1-((S)-7-Oxo-4-oxa-1-aza-bicyclo[3.2.0]hept-6-ylcarbamoyl)-2-phenyl-propyl]-carbamic acid benzyl ester


name: [(S)-1-((S)-3-Benzyloxy-2-oxo-1-phenethyl-propylcarbamoyl)-3-methyl-butyl]-carbamic acid benzyl ester


name: [(S)-1-((S)-3-Hydroxy-2-oxo-1-phenethyl-propylcarbamoyl)-2-methyl-butyl]-carbamic acid benzyl ester


name: Acetic acid (2S,3S)-3-[(1-benzyloxycarbonylamino-cyclohexanecarbonyl)-amino]-4-oxo-azetidin-2-yl ester


name: [5-(3-Isopropyl-phenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]-carbamic acid methyl ester


name: 3,5-Dihydroxy-4-(2-hydroxy-6-methoxycarbonyl-benzoyl)-benzoic acid (1R,2R)-2-(4-hydroxy-benzoylamino)-cyclopentyl ester


DEXVERAPAMIL

A 2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile that has R configuration. It competitively inhibits the multidrug resistance efflux pump P-glycoprotein (MDR-1, EC 3.6.3.44), thereby potentially increasing the effectiveness of a wide range of antineoplastic drugs which are inactivated by MDR-1 mechanisms. Dexverapamil exhibits lower calcium antagonistic activity and toxicity than racemic verapamil.


name: 9-Carbamoyl-4-{4-[2-(3,4-difluoro-phenyl)-ethyl]-piperazin-1-yl}-pyrimido[5,4-b]indole-5-carboxylic acid ethyl ester


name: 4-{4-[2-(3,4-Difluoro-phenyl)-ethyl]-piperazin-1-yl}-5H-pyrimido[5,4-b]indole-8-carboxylic acid methyl ester


name: (4-{4-[2-(3,4-Difluoro-phenyl)-ethyl]-piperazin-1-yl}-8-nitro-pyrimido[5,4-b]indol-5-yl)-acetic acid ethyl ester


(S)-VERAPAMIL

A 2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile that has S configuration.


name: (9-Carbamoyl-4-{4-[2-(3,4-difluoro-phenyl)-ethyl]-piperazin-1-yl}-pyrimido[5,4-b]indol-5-yl)-acetic acid ethyl ester


17beta-estradiol 3-sulfate

A steroid sulfate obtained by the formal condensation of sulfuric acid with the 3-hydroxy group of 17beta-estradiol.


ivermectin

A mixture consisting of >= 90% 22,23-dihydroavermectin B1a (R = Me) and <= 10% 22,23-dihydroavermectin B1b (R = H). A semi-synthetic derivative of abamectin, it is used as a broad-spectrum antiparasite medication, particularly against worms (except tapeworms), although it is also effective against most mites and some lice.


name: 4-(4-Phenethyl-piperazin-1-yl)-6,7,8,9-tetrahydro-pyrimido[4,5-b]indolizine-10-carboxylic acid methyl ester


name: 3-{5-[(Z)-Cyclohexylimino]-4-methyl-4,5-dihydro-[1,3,4]thiadiazol-2-yl}-benzoic acid methyl ester


name: 4-{5-[(Z)-Cyclohexylimino]-4-methyl-4,5-dihydro-[1,3,4]thiadiazol-2-yl}-benzoic acid methyl ester


rigosertib

An N-[2-methoxy-5-({[2-(2,4,6-trimethoxyphenyl)ethenyl]sulfonyl}methyl)phenyl]glycine in which the double bond has E-configuration. It is a non-ATP-competitive inhibitor of PLK1 with an IC50 of 9 nM and exhibits anti-cancer properties.


SULFAMIDE

The simplest of the sulfamic acids consisting of a single sulfur atom covalently bound by single bonds to two amino groups and by double bonds to two oxygen atoms.


SULFAMATE

The simplest of the sulfamic acids consisting of a single sulfur atom covalently bound by single bonds to hydroxy and amino groups and by double bonds to two oxygen atoms.


N-OXALYLGLYCINE

An amino dicarboxylic acid that is iminodiacetic acid with an oxo substituent. It is used as an inhibitor of alpha-ketoglutarate dependent (EC 1.14.11.*) enzymes.


name: ((S)-1-Formyl-pentyl)-carbamic acid (S)-1-benzyl-propyl ester


name: {(S)-1-[(morpholine-4-carbonyl)-hydrazonomethyl]-pentyl}-carbamic acid (R)-1-benzyl-2-methyl-propyl ester


name: {(S)-3-Methyl-1-[3-oxo-1-(4-phenoxy-benzenesulfonyl)-piperidin-4-ylcarbamoyl]-butyl}-carbamic acid benzyl ester


name: ((S)-1-Formyl-pentyl)-carbamic acid 1-isopropyl-2-methyl-propyl ester


name: [(S)-1-((R)-1-Phenyl-ethylaminooxalyl)-pentyl]-carbamic acid 1-tert-butyl-2,2-dimethyl-propyl ester


name: [(S)-1-((R)-1-Phenyl-ethylaminooxalyl)-pentyl]-carbamic acid (R)-1-tert-butyl-4-phenyl-butyl ester


name: ((S)-1-Formyl-pentyl)-carbamic acid 1-propyl-butyl ester


name: {(S)-1-[(morpholine-4-carbonyl)-hydrazonomethyl]-pentyl}-carbamic acid (S)-1-methyl-2-phenyl-ethyl ester


name: [(S)-1-((R)-1-Phenyl-ethylaminooxalyl)-pentyl]-carbamic acid (R)-2,2-dimethyl-1-phenethyl-propyl ester


name: ((S)-1-Formyl-pentyl)-carbamic acid 1-isobutyl-3-methyl-butyl ester


name: ((S)-1-Formyl-pentyl)-carbamic acid (S)-1-benzyl-butyl ester


name: [1-(1H-Pyrazol-3-ylaminooxalyl)-pentyl]-carbamic acid 2,2-dimethyl-butyl ester


name: 3-[(S)-3-(1-Isopropyl-2-methyl-propoxycarbonylamino)-2-oxo-heptanoylamino]-1H-pyrazole-4-carboxylic acid ethyl ester


name: [1-(1H-Pyrazol-3-ylaminooxalyl)-pentyl]-carbamic acid 1-ethyl-cyclopentylmethyl ester


name: [1-(1H-Pyrazol-3-ylaminooxalyl)-pentyl]-carbamic acid 1-ethyl-cyclobutylmethyl ester


name: ((S)-1-Formyl-pentyl)-carbamic acid 1-benzyl-cyclohexyl ester


name: ((S)-1-Formyl-pentyl)-carbamic acid 1-benzyl-1-ethyl-propyl ester


name: ((S)-1-Formyl-pentyl)-carbamic acid 1-benzyl-cyclobutyl ester


name: [(S)-1-((R)-1-Phenyl-ethylaminooxalyl)-pentyl]-carbamic acid 1-isopropyl-2-methyl-propyl ester


name: ((S)-1-Formyl-pentyl)-carbamic acid 2-(4-methoxy-phenyl)-1,1-dimethyl-ethyl ester


name: ((R)-2-Phenyl-1-{3-phenyl-1-[(4-piperidin-1-yl-phenylamino)-methyl]-propylcarbamoyl}-ethyl)-carbamic acid benzyl ester


name: ((S)-1-Formyl-pentyl)-carbamic acid 2-(2-chloro-phenyl)-1,1-dimethyl-ethyl ester


name: ((S)-1-Formyl-pentyl)-carbamic acid 1-ethyl-propyl ester


name: ((R)-2-Methyl-1-{3-phenyl-1-[(4-piperidin-1-yl-phenylamino)-methyl]-propylcarbamoyl}-propyl)-carbamic acid benzyl ester


name: ((S)-1-Formyl-pentyl)-carbamic acid 2-(4-chloro-phenyl)-1,1-dimethyl-ethyl ester


name: ((S)-1-Formyl-pentyl)-carbamic acid 1-isopropyl-1,2-dimethyl-propyl ester


name: [4-((S)-2-{[1-(biphenyl-3-ylamino)-cyclohexanecarbonyl]-amino}-butylamino)-phenoxy]-acetic acid tert-butyl ester


name: ((R)-3-Methyl-1-{3-phenyl-1-[(4-piperidin-1-yl-phenylamino)-methyl]-propylcarbamoyl}-butyl)-carbamic acid benzyl ester


name: [1-((S)-7-Oxo-4-oxa-1-aza-bicyclo[3.2.0]hept-6-ylcarbamoyl)-2-phenyl-ethyl]-carbamic acid benzyl ester


name: [(S)-1-(Isoxazol-3-ylaminooxalyl)-pentyl]-carbamic acid 1-isopropyl-2-methyl-propyl ester


name: ((S)-1-Formyl-pentyl)-carbamic acid 2-(3-methoxy-phenyl)-1,1-dimethyl-ethyl ester


name: [(S)-1-((R)-1-Phenyl-ethylaminooxalyl)-pentyl]-carbamic acid dicyclopentylmethyl ester


name: ((S)-1-Formyl-pentyl)-carbamic acid (S)-1-benzyl-3-methyl-butyl ester


name: (4-{(S)-2-[(S)-2-(biphenyl-3-ylamino)-4-methyl-pentanoylamino]-butylamino}-phenoxy)-acetic acid tert-butyl ester


name: ((S)-1-Formyl-pentyl)-carbamic acid 1,1-dimethyl-2-(3-thiophen-3-yl-phenyl)-ethyl ester


name: CAC1 proteinases 5,5 bicyclic inhibitor 10


name: ((R)-1-{3-Phenyl-1-[(4-piperidin-1-yl-phenylamino)-methyl]-propylcarbamoyl}-ethyl)-carbamic acid benzyl ester


name: (1-Cyano-pyrrolidin-3-yl)-carbamic acid (S)-1-cyclohexylmethyl-propyl ester


name: {(S)-1-[(S)-1-Benzyl-2-(4-piperidin-1-yl-phenylamino)-ethylcarbamoyl]-3-methyl-butyl}-carbamic acid benzyl ester


name: ((S)-1-Formyl-pentyl)-carbamic acid 1,1-dimethyl-2-phenyl-ethyl ester


name: 2-{(S)-3-Phenyl-1-[(4-piperidin-1-yl-phenylamino)-methyl]-propylcarbamoyl}-pyrrolidine-1-carboxylic acid benzyl ester


name: (1-Cyano-pyrrolidin-3-yl)-carbamic acid (S)-2-cyclohexyl-1-methyl-ethyl ester


name: {(S)-1-Cyclohexylmethyl-2-oxo-2-[(thiophen-2-ylmethyl)-carbamoyl]-ethyl}-carbamic acid 1-isopropyl-2-methyl-propyl ester


name: ((R)-3-Phenyl-1-{3-phenyl-1-[(4-piperidin-1-yl-phenylamino)-methyl]-propylcarbamoyl}-propyl)-carbamic acid benzyl ester


name: ((S)-5-tert-Butoxycarbonylamino-6-oxo-hexyl)-carbamic acid methyl ester


name: ((S)-1-Formyl-4-phenyl-butyl)-carbamic acid tert-butyl ester


name: {(S)-1-[(S)-1-Benzyl-2-(4-morpholin-4-yl-phenylamino)-ethylcarbamoyl]-3-methyl-butyl}-carbamic acid benzyl ester


name: [(S)-1-((3S,4R)-2-Oxo-4-phenoxy-azetidin-3-ylcarbamoyl)-2-phenyl-ethyl]-carbamic acid benzyl ester


name: ((S)-4-Cyclohexyl-1-formyl-butyl)-carbamic acid tert-butyl ester


name: [1-(1H-Pyrazol-3-ylaminooxalyl)-pentyl]-carbamic acid 1-ethyl-cyclohexylmethyl ester


name: [1-((S)-1-Cyano-pyrrolidin-3-ylcarbamoyl)-3-methyl-butyl]-carbamic acid cyclohexylmethyl ester


name: [(S)-1-((R)-1-Phenyl-ethylaminooxalyl)-pentyl]-carbamic acid 1,2,2-trimethyl-propyl ester


name: (1-Cyano-pyrrolidin-3-yl)-carbamic acid benzyl ester


name: [1-(Isoxazol-3-ylaminooxalyl)-pentyl]-carbamic acid 1-ethyl-cyclobutylmethyl ester


name: ((S)-1-Formyl-heptyl)-carbamic acid tert-butyl ester


name: {(S)-1-[(2,2,2-trifluoro-acetyl)-hydrazonomethyl]-pentyl}-carbamic acid tert-butyl ester


name: {(S)-3-Methyl-1-[1-(4-methyl-pentyl)-3-oxo-piperidin-4-ylcarbamoyl]-butyl}-carbamic acid benzyl ester


name: [1-(Isoxazol-3-ylaminooxalyl)-pentyl]-carbamic acid 2,2-dimethyl-butyl ester


name: ((S)-3-Cyclohexyl-1-formyl-propyl)-carbamic acid tert-butyl ester


name: (Cyano-methyl-amino)-acetic acid (S)-2-cyclohexyl-1-methyl-ethyl ester


name: {(S)-1-Benzyl-2-oxo-2-[(thiophen-2-ylmethyl)-carbamoyl]-ethyl}-carbamic acid 1-isopropyl-2-methyl-propyl ester


name: {(S)-1-Formyl-4-[methyl-(2,2,2-trifluoro-acetyl)-amino]-butyl}-carbamic acid tert-butyl ester


name: {(S)-3-Methyl-1-[4-oxo-1-(4-phenoxy-benzoyl)-pyrrolidin-3-ylcarbamoyl]-butyl}-carbamic acid benzyl ester


name: [(S)-1-((R)-1-Phenyl-ethylaminooxalyl)-pentyl]-carbamic acid 1-propyl-butyl ester


name: {(S)-1-[(morpholine-4-carbonyl)-hydrazonomethyl]-pentyl}-carbamic acid tert-butyl ester


name: {(S)-1-[2-(4-Isobutoxy-phenylamino)-ethylcarbamoyl]-3-methyl-butyl}-carbamic acid benzyl ester


name: [1-(1-Phenyl-ethylaminooxalyl)-pentyl]-carbamic acid 2,2-dimethyl-butyl ester


name: {(S)-1-[(pyrrolidine-1-carbonyl)-hydrazonomethyl]-pentyl}-carbamic acid tert-butyl ester


name: [1-(1-Phenyl-ethylaminooxalyl)-pentyl]-carbamic acid 1-(thiazol-2-yloxymethyl)-cyclobutylmethyl ester


name: ((R)-2-Benzylsulfanyl-1-formyl-ethyl)-carbamic acid tert-butyl ester


name: [(S)-1-Formyl-5-(2,2,2-trifluoro-acetylamino)-pentyl]-carbamic acid tert-butyl ester


name: {(S)-1-[2-(4-Cyclohexyloxy-phenylamino)-ethylcarbamoyl]-3-methyl-butyl}-carbamic acid benzyl ester


name: {(S)-1-[2-(4-Cyclopentylmethoxy-phenylamino)-ethylcarbamoyl]-3-methyl-butyl}-carbamic acid benzyl ester


name: {(S)-1-Formyl-5-[methyl-(2,2,2-trifluoro-acetyl)-amino]-pentyl}-carbamic acid tert-butyl ester


name: Carbamic acid, [(1S)-1-formylpentyl]-, 1,1-dimethylethyl ester


name: [1-(1-Phenyl-ethylaminooxalyl)-pentyl]-carbamic acid 1-(benzooxazol-2-ylsulfanylmethyl)-cyclobutylmethyl ester


name: {(S)-1-[2-(4-Benzyloxy-phenylamino)-ethylcarbamoyl]-3-methyl-butyl}-carbamic acid benzyl ester


name: [1-(1-Phenyl-ethylaminooxalyl)-pentyl]-carbamic acid 1-(2-morpholin-4-yl-pyrimidin-4-yloxymethyl)-cyclobutylmethyl ester


name: {(S)-1-[(piperidine-1-carbonyl)-hydrazonomethyl]-pentyl}-carbamic acid tert-butyl ester


name: {(S)-1-[2-(4-Methoxy-phenylamino)-ethylcarbamoyl]-3-methyl-butyl}-carbamic acid benzyl ester


name: (S)-1-Cyano-pyrrolidine-2-carboxylic acid tert-butyl ester


name: [1-(1-Phenyl-ethylaminooxalyl)-pentyl]-carbamic acid 3-ethyl-oxetan-3-ylmethyl ester


name: [1-(1-Phenyl-ethylaminooxalyl)-pentyl]-carbamic acid 1-ethyl-cyclopentylmethyl ester


name: {(S)-1-[2-(4-Cyclopropylmethoxy-phenylamino)-ethylcarbamoyl]-3-methyl-butyl}-carbamic acid benzyl ester


name: ((S)-1-Formyl-pentyl)-carbamic acid 1-benzyl-2-phenyl-ethyl ester


name: [1-(1-Phenyl-ethylaminooxalyl)-pentyl]-carbamic acid 1-ethyl-cyclobutylmethyl ester


name: [(S)-1-((3R,4R)-2-Oxo-4-phenylsulfanyl-azetidin-3-ylcarbamoyl)-2-phenyl-ethyl]-carbamic acid benzyl ester


name: [(S)-1-((R)-1-Phenyl-ethylaminooxalyl)-pentyl]-carbamic acid 1-ethyl-propyl ester


name: ((S)-1-Formyl-3-methyl-but-3-enyl)-carbamic acid tert-butyl ester


name: {(S)-1-[2-(4-Cyclopentyloxy-phenylamino)-ethylcarbamoyl]-3-methyl-butyl}-carbamic acid benzyl ester


name: ((R)-2-Ethylsulfanyl-1-formyl-ethyl)-carbamic acid tert-butyl ester


name: ((S)-5,5,5-Trifluoro-1-formyl-pentyl)-carbamic acid tert-butyl ester


name: [1-(1-Phenyl-ethylaminooxalyl)-pentyl]-carbamic acid 1-(1-phenyl-1H-imidazol-2-ylsulfanylmethyl)-cyclobutylmethyl ester


name: CAC1 proteinases 5,5 bicyclic inhibitor 45a


name: {(S)-1-[(3,4-dihydro-1H-isoquinoline-2-carbonyl)-hydrazonomethyl]-pentyl}-carbamic acid tert-butyl ester


name: {(S)-1-Formyl-3-[methyl-(2,2,2-trifluoro-acetyl)-amino]-propyl}-carbamic acid tert-butyl ester


name: [1-(1-Phenyl-ethylaminooxalyl)-pentyl]-carbamic acid 1-(thieno[3,2-d]pyrimidin-4-yloxymethyl)-cyclobutylmethyl ester


name: ((S)-1-Formyl-pentyl)-carbamic acid (R)-1-methyl-2-phenyl-ethyl ester


name: ((S)-1-Formyl-hexyl)-carbamic acid tert-butyl ester


name: [1-(Isoxazol-3-ylaminooxalyl)-pentyl]-carbamic acid 1-ethyl-cyclohexylmethyl ester


name: ((R)-1-Formyl-2-methyl-butyl)-carbamic acid tert-butyl ester


name: N''-[(S)-2-tert-butoxycarbonylamino-hexylidene]-hydrazinecarboxylic acid isopropyl ester


name: [1-(1-Phenyl-ethylaminooxalyl)-pentyl]-carbamic acid 1-ethyl-cyclohexylmethyl ester


name: ((S)-1-Formyl-pent-3-enyl)-carbamic acid tert-butyl ester


name: ((S)-3-Methyl-1-{2-[4-(pyridin-4-ylmethoxy)-phenylamino]-ethylcarbamoyl}-butyl)-carbamic acid benzyl ester


name: [1-(1-Phenyl-ethylaminooxalyl)-pentyl]-carbamic acid 1-(4-p-tolyl-thiazol-2-yloxymethyl)-cyclobutylmethyl ester


name: Acetic acid (2S,3S)-3-[(1-benzyloxycarbonylamino-cyclopentanecarbonyl)-amino]-4-oxo-azetidin-2-yl ester


name: ((S)-3-Methyl-1-{2-[4-(tetrahydro-pyran-4-yloxy)-phenylamino]-ethylcarbamoyl}-butyl)-carbamic acid benzyl ester


name: [3-Methyl-1-(2-p-tolylamino-ethylcarbamoyl)-butyl]-carbamic acid benzyl ester


name: 2-((2S,3S)-2-Acetoxy-4-oxo-azetidin-3-ylcarbamoyl)-piperidine-1-carboxylic acid benzyl ester


name: 3-Cyanoamino-pyrrolidine-1-carboxylic acid (S)-1-cyclohexylmethyl-propyl ester


name: {(S)-1-[(3-methyl-butyryl)-hydrazonomethyl]-pentyl}-carbamic acid tert-butyl ester


name: [(S)-1-(benzoyl-hydrazonomethyl)-pentyl]-carbamic acid tert-butyl ester


name: [(S)-1-(Quinolin-2-ylaminooxalyl)-pentyl]-carbamic acid 1-isopropyl-2-methyl-propyl ester


name: ((S)-1-Formyl-3,3-dimethyl-butyl)-carbamic acid tert-butyl ester


name: ((S)-1-Formyl-2-methyl-butyl)-carbamic acid tert-butyl ester


name: [1-(1-Phenyl-ethylaminooxalyl)-pentyl]-carbamic acid 1-(pyrimidin-2-yloxymethyl)-cyclobutylmethyl ester


name: ((S)-1-Formyl-pentyl)-carbamic acid phenethyl ester


name: {(S)-3-Methyl-1-[2-(4-phenoxy-phenylamino)-ethylcarbamoyl]-butyl}-carbamic acid benzyl ester


name: (R)-1-Cyano-pyrrolidine-2-carboxylic acid tert-butyl ester


name: {1-[2-(4-Chloro-phenylamino)-ethylcarbamoyl]-3-methyl-butyl}-carbamic acid benzyl ester


name: [1-(Isoxazol-3-ylaminooxalyl)-pentyl]-carbamic acid 3-ethyl-oxetan-3-ylmethyl ester


name: {(S)-1-Methyl-2-oxo-2-[(thiophen-2-ylmethyl)-carbamoyl]-ethyl}-carbamic acid 1-isopropyl-2-methyl-propyl ester


name: ((S)-2-tert-Butoxycarbonylamino-3-oxo-propyl)-carbamic acid methyl ester


name: [1-((3S,4S)-2-Oxo-4-phenoxy-azetidin-3-ylcarbamoyl)-cyclohexyl]-carbamic acid benzyl ester


name: 2-Cyano-pyrazolidine-1-carboxylic acid tert-butyl ester


name: ((S)-1-Formyl-pent-3-ynyl)-carbamic acid tert-butyl ester


name: [3-Methyl-1-(2-m-tolylamino-ethylcarbamoyl)-butyl]-carbamic acid benzyl ester


name: [3-Methyl-1-(2-phenylamino-ethylcarbamoyl)-butyl]-carbamic acid benzyl ester


name: {(S)-1-[(4,5-dihydro-thiazol-3-yl)-hydrazonomethyl]-pentyl}-carbamic acid tert-butyl ester


name: ((S)-1-Formyl-pentyl)-carbamic acid benzyl ester


name: ((S)-1-Formyl-pentyl)-carbamic acid 3-phenyl-propyl ester


name: [(S)-1-((S)-3-Methoxy-2-oxo-1-phenethyl-propylcarbamoyl)-3-methyl-butyl]-carbamic acid benzyl ester


name: ((S)-1-Formyl-3-methoxy-propyl)-carbamic acid tert-butyl ester


name: {(S)-1-[(S)-1-Benzyl-2-(biphenyl-4-ylamino)-ethylcarbamoyl]-3-methyl-butyl}-carbamic acid benzyl ester


name: [(S)-1-(isopropylsulfanylcarbonyl-hydrazonomethyl)-pentyl]-carbamic acid tert-butyl ester


name: ((S)-1-{2-[4-(2-Imidazol-1-yl-ethoxy)-phenylamino]-ethylcarbamoyl}-3-methyl-butyl)-carbamic acid benzyl ester


name: {(S)-3-Methyl-1-[3-oxo-4-(4-phenoxy-benzoylamino)-pyrrolidine-1-carbonyl]-butyl}-carbamic acid benzyl ester


name: [(S)-1-((R)-1-Phenyl-ethylaminooxalyl)-pentyl]-carbamic acid (S)-2,2-dimethyl-1-phenethyl-propyl ester


name: [(S)-1-((S)-3-Ethoxy-2-oxo-1-phenethyl-propylcarbamoyl)-3-methyl-butyl]-carbamic acid benzyl ester


name: 2-((2S,3S)-2-Acetoxy-4-oxo-azetidin-3-ylcarbamoyl)-pyrrolidine-1-carboxylic acid benzyl ester


name: ((S)-3-Methyl-1-{2-[4-(1-methyl-piperidin-4-yloxy)-phenylamino]-ethylcarbamoyl}-butyl)-carbamic acid benzyl ester


N-oleoyl-L-leucine

An L-leucine derivative resulting from the formal condensation of the carboxy group of oleic acid with the amino group of L-leucine.


N-oleoyl-L-phenylalanine

An N-acyl-L-phenylalanine resulting from the formal condensation of the carboxy group of oleic acid with the amino group of L-phenylalanine.


(R)-oleoylcarnitine

An O-acyl-L-carnitine in which the acyl group is specified as oleoyl.


OLEOYL GLYCINE

A fatty acid derivative that is the 9Z-octadecenoyl derivative of glycine. It is believed to be an intermediate in oleamide biosynthesis.


N-oleoyl-L-serine

An L-serine derivative resulting from the formal condensation of the carboxy group of oleic acid with the amino group of L-serine.


O-palmitoyl-L-carnitine

An O-acyl-L-carnitine in which the acyl group is specified as palmitoyl (hexadecanoyl).


name: 4-(2-Carbamoyl-thieno[2,3-c]pyridin-4-yloxy)-benzoic acid ethyl ester


name: 3-(2-Carbamoyl-thieno[2,3-c]pyridin-4-yloxy)-benzoic acid ethyl ester


name: [4-(4-Amino-phenoxy)-phenyl]-(3-hydroxycarbamoyl-3,4-dihydro-1H-isoquinolin-2-yl)-phosphinic acid ethyl ester


name: (3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquinolin-2-yl)-(4-phenoxy-phenyl)-phosphinic acid ethyl ester


name: (3-Hydroxycarbamoyl-1,3,4,9-tetrahydro-beta-carbolin-2-yl)-(4-methoxy-phenyl)-phosphinic acid ethyl ester


name: (3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquinolin-2-yl)-(4-methoxy-phenyl)-phosphinic acid cyclohexylmethyl ester


name: (3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquinolin-2-yl)-(4-methoxy-phenyl)-phosphinic acid methyl ester


name: 10-Hydroxycarbamoyl-9-isobutyl-6-methylcarbamoyl-8-oxo-1,7diaza-cyclotridecane-1-carboxylic acid tert-butyl ester


name: 7-Benzenesulfonyl-12-isobutyl-13-oxo-1,7diaza-cyclotridecane-2,11-dicarboxylic acid 11-hydroxyamide 2-methylamide


name: Biphenyl-4-yl-(3-hydroxycarbamoyl-3,4-dihydro-1H-isoquinolin-2-yl)-phosphinic acid ethyl ester


name: (3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquinolin-2-yl)-[4-(pyridin-4-yloxy)-phenyl]-phosphinic acid ethyl ester


name: (3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquinolin-2-yl)-(4-methoxy-phenyl)-phosphinic acid hexyl ester


name: 3-Hydroxycarbamoyl-4-(4-methoxy-benzenesulfonyl)-piperazine-1-carboxylic acid 3-ethoxy-propyl ester


name: (6-Hydroxycarbamoyl-6,7-dihydro-4H-thieno[3,2-c]pyridin-5-yl)-(4-methoxy-phenyl)-phosphinic acid ethyl ester


name: (3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquinolin-2-yl)-(4-methoxy-phenyl)-phosphinic acid 2-ethoxy-ethyl ester


name: (3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquinolin-2-yl)-(4-methoxy-phenyl)-phosphinic acid 2-pyridin-2-yl-ethyl ester


name: (3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquinolin-2-yl)-(4-methoxy-phenyl)-phosphinic acid 2,2-difluoro-ethyl ester


name: (3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquinolin-2-yl)-(4-methoxy-phenyl)-phosphinic acid 2,2,2-trifluoro-ethyl ester


name: (3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquinolin-2-yl)-(4-methoxy-phenyl)-phosphinic acid phenethyl ester


name: 3-Hydroxycarbamoyl-4-(4-methoxy-benzenesulfonyl)-piperazine-1-carboxylic acid pyridin-3-ylmethyl ester


name: (7-Hydroxycarbamoyl-7,8-dihydro-5H-pyrido[3,4-b]pyrazin-6-yl)-(4-methoxy-phenyl)-phosphinic acid ethyl ester


name: (3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquinolin-2-yl)-phenethyl-phosphinic acid ethyl ester


name: (7-Amino-3-hydroxycarbamoyl-3,4-dihydro-1H-isoquinolin-2-yl)-(4-methoxy-phenyl)-phosphinic acid ethyl ester


name: (3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquinolin-2-yl)-(4-methoxy-phenyl)-phosphinic acid 2-biphenyl-4-yl-ethyl ester


name: 4-[Carboxy-(4''-methoxy-biphenyl-4-sulfonylamino)-methyl]-piperidine-1-carboxylic acid 2-methoxy-ethyl ester


name: (R)-5-Hydroxycarbamoyl-4-(4-methoxy-benzenesulfonyl)-[1,4]diazepane-1-carboxylic acid benzyl ester


name: 4-[Ethoxy-(4-methoxy-phenyl)-phosphinoyl]-3-hydroxycarbamoyl-piperazine-1-carboxylic acid benzyl ester


name: 4-(4-Methoxy-benzenesulfonyl)-piperazine-1,3-dicarboxylic acid 1-amide 3-hydroxyamide


name: [3-Hydroxycarbamoyl-2-(4-methoxy-benzenesulfonyl)-1,2,3,4-tetrahydro-isoquinolin-7-yl]-carbamic acid tert-butyl ester


name: Carbonic acid ethyl ester 3-hydroxycarbamoyl-2-(4-methoxy-benzenesulfonyl)-1,2,3,4-tetrahydro-isoquinolin-7-yl ester


name: {(S)-3-[(R)-2-((R)-1-Hydroxycarbamoyl-ethyl)-decanoylamino]-2-oxo-azepan-1-yl}-acetic acid methyl ester


name: 12-Isobutyl-3,11-dioxo-1-oxa-4,10-diaza-cyclotridecane-9,13-dicarboxylic acid 13-hydroxyamide 9-methylamide (SC903)


name: (3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquinolin-2-yl)-(4-methoxy-phenyl)-phosphinic acid butyl ester


name: (3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquinolin-2-yl)-(4-methoxy-phenyl)-phosphinic acid isopropyl ester


name: 4-(4-Methoxy-benzenesulfonyl)-piperazine-1,3-dicarboxylic acid 1-hexylamide 3-hydroxyamide


name: [4-(2-Ethoxy-ethoxy)-phenyl]-(3-hydroxycarbamoyl-3,4-dihydro-1H-isoquinolin-2-yl)-phosphinic acid ethyl ester


name: (3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquinolin-2-yl)-styryl-phosphinic acid ethyl ester


name: (3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquinolin-2-yl)-phenyl-phosphinic acid ethyl ester


name: 4-[Carboxy-(4''-methoxy-biphenyl-4-sulfonylamino)-methyl]-piperidine-1-carboxylic acid isopropyl ester


name: (2-Fluoro-phenyl)-(3-hydroxycarbamoyl-3,4-dihydro-1H-isoquinolin-2-yl)-phosphinic acid ethyl ester


name: (3-Fluoro-phenyl)-(3-hydroxycarbamoyl-3,4-dihydro-1H-isoquinolin-2-yl)-phosphinic acid ethyl ester


name: 4-[Carboxy-(4'-methoxy-biphenyl-4-sulfonylamino)-methyl]-piperidine-1-carboxylic acid tert-butyl ester


name: [(S)-3-((2R,3R)-3-Hydroxycarbamoyl-2-isobutyl-hexanoylamino)-2-oxo-azepan-1-yl]-acetic acid methyl ester


name: 3-Hydroxycarbamoyl-4-(4-methoxy-benzenesulfonyl)-piperazine-1-carboxylic acid tert-butyl ester


name: 3-[2-Hydroxycarbamoyl-1-(4-methoxy-benzenesulfonyl)-ethyl]-cyclohexanecarboxylic acid ethyl ester


name: (4-Fluoro-phenyl)-(3-hydroxycarbamoyl-3,4-dihydro-1H-isoquinolin-2-yl)-phosphinic acid ethyl ester


name: (3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquinolin-2-yl)-thiophen-2-yl-phosphinic acid ethyl ester


name: 4-{Carboxy-[(4''-methoxy-biphenyl-4-sulfonyl)-methyl-amino]-methyl}-piperidine-1-carboxylic acid 2-methoxy-ethyl ester


name: (3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquinolin-2-yl)-p-tolyl-phosphinic acid ethyl ester


name: (3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquinolin-2-yl)-(4-methoxy-phenyl)-phosphinic acid 2-diethylamino-ethyl ester


name: (S)-2-[(R)-2-((R)-1-Hydroxy-1-hydroxycarbamoyl-ethyl)-5-phenyl-pentanoylamino]-3-phenyl-propionic acid tert-butyl ester


name: {(R)-3-[(Biphenyl-4-sulfonyl)-isopropoxy-amino]-3-hydroxycarbamoyl-propyl}-carbamic acid benzyl ester


name: 4-[Carboxy-(4''-methoxy-biphenyl-4-sulfonylamino)-methyl]-piperidine-1-carboxylic acid ethyl ester


name: (4-Amino-phenyl)-(3-hydroxycarbamoyl-3,4-dihydro-1H-isoquinolin-2-yl)-phosphinic acid ethyl ester


name: (3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquinolin-2-yl)-pyridin-4-yl-phosphinic acid ethyl ester


name: {(S)-3-[(R)-2-((R)-1-Hydroxycarbamoyl-ethyl)-4-methyl-pentanoylamino]-2-oxo-azepan-1-yl}-acetic acid methyl ester


name: 4-[Carboxy-(4-phenoxy-benzenesulfonylamino)-methyl]-piperidine-1-carboxylic acid 2-methoxy-ethyl ester


name: [4-(3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquinoline-2-sulfonyl)-phenyl]-carbamic acid benzyl ester


name: 4-[(Biphenyl-4-sulfonylamino)-carboxy-methyl]-piperidine-1-carboxylic acid 2-methoxy-ethyl ester


name: 5-Mercapto-5-[(S)-3-methyl-1-((S)-1-methylcarbamoyl-2-phenyl-ethylcarbamoyl)-butylcarbamoyl]-pentanoic acid methyl ester


name: [4-(3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquinoline-2-sulfonyl)-phenyl]-carbamic acid ethyl ester


name: (2-Hydroxycarbamoyl-pyrrolidin-1-yl)-(4-methoxy-phenyl)-phosphinic acid ethyl ester


name: 4-[Carboxy-(4''-methoxy-biphenyl-4-sulfonylamino)-methyl]-piperidine-1-carboxylic acid methyl ester


name: 4-[(4-Butoxy-benzenesulfonylamino)-carboxy-methyl]-piperidine-1-carboxylic acid 2-methoxy-ethyl ester


name: 5-(3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquinoline-2-sulfonyl)-4-methoxy-thiophene-3-carboxylic acid methyl ester


name: (S)-2-((R)-2-Hydroxycarbamoylmethyl-4-methyl-pentanoyl)-hexahydro-pyridazine-3-carboxylic acid methyl ester


name: [(S)-3-((R)-2-Hydroxycarbamoylmethyl-heptanoylamino)-2-oxo-azepan-1-yl]-acetic acid methyl ester


name: 2-(4-(2-Trifluoromethylphenyl)piperidine-1-yl)-6-methylpyrimidine-4-carboxylic acid methyl ester


name: Acetic acid, 2-[4-[(15-oxoretin-15-yl)amino]phenoxy]-, methyl ester


FENRETINIDE

A retinoid obtained by formal condensation of the carboxy group of all-trans retinoic acid and the anilino group of 4-hydroxyaniline. Synthetic retinoid agonist. Antiproliferative, antioxidant and anticancer agent with a long half-life in vivo. Apoptotic effects appear to be mediated by a mechanism distinct from that of 'classical' retinoids.


talazoparib tosylate

Talazoparib is an orally available small molecule inhibitor of the DNA repair enzyme poly ADP-ribose polymerase (PARP) which is used as an antineoplastic agent in the treatment of selected cases of breast cancer. Talazoparib is associated with a moderate rate of serum aminotransferase elevations during therapy and is suspected to cause rare instances of clinically apparent acute liver injury.


veliparib

A benzimidazole substituted with a carbamoyl group at C-4 and a (2R)-2-methylpyrrolidin-2-yl moiety at C-2.  It is a potent, orally bioavailable PARP inhibitor.


A 2-[4-(piperidin-3-yl)phenyl]-2H-indazole-7-carboxamide that has R-configuration. It is a potent PARP1 inhibitor with IC50 of 2.4 nM.


A member of the class of indazoles that is 2H-indazole substituted by 4-(piperidin-3-yl)phenyl and aminocarbonyl groups at positions 2 and 7, respectively. It is a potent PARP1 inhibitor with IC50 of 3.2 nM.


mefuparib

A member of the class of 1-benzofurans that is 1-benzofuran substituted by 4-[(methylamino)methyl]phenyl, fluoro and aminocarbonyl groups at positions 2, 5, and 7, respectively. It is a potent inhibitor of poly(ADP-ribose) polymerases PARP1 and PARP2 (IC50 of 3.2 nM and 1.9 nM, respectively). The compound exhibits anti-cancer properties and has also shown promising antiviral activity against the virus that causes COVID-19.


name: 4-(4-Carbamoyl-1H-benzoimidazol-2-yl)-benzoic acid ethyl ester


A member of the class of phenanthridines that is 5,6-dihydrophenanthridine substituted at positions 2 and 6 by (N,N-dimethylglycyl)amino and oxo groups, respectively. It is a potent inhibitor of poly(ADP-ribose) polymerases PARP1 and PARP2 (IC50 of 110 nM and 86 nM, respectively) and exhibits anti-cancer, cardioprotective and neuroprotective properties.


A thiopyranopyrimidine in which a 7,8-dihydro-5H-thiopyrano[4,3-d]pyrimidine skeleton is substituted at C-4 by a hydroxy group and at C-2 by a para-(trifluoromethyl)phenyl group.


name: 6-Oxo-5,6-dihydro-phenanthridine-2-sulfonic acid (2-piperidin-1-yl-ethyl)-amide hydrochloride


name: 8-Fluoro-6-oxo-5,6-dihydro-phenanthridine-3-carboxylic acid methyl ester


name: 2-(2,5-Diaza-bicyclo[2.2.1]hept-2-yl)-5H-benzo[c][1,5]naphthyridin-6-one; Trifluoro-acetic acid anion


NU 1025

A member of the class of  quinazolines that is quinazolin-4(1H)-one substituted by a hydroxy group at position 8 and a methyl group at position 2. It has been shown to exhibit inhibitory activity against  poly(ADP-ribose) polymerase.


name: 2-Piperazin-1-yl-5H-benzo[c][1,5]naphthyridin-6-one; compound with methanesulfonic acid


name: 2-(4-Cyclopropylmethyl-piperazin-1-yl)-5H-benzo[c][1,5]naphthyridin-6-one; compound with methanesulfonic acid


name: [3-(4-Oxo-3,4-dihydro-phthalazin-1-ylmethyl)-phenyl]-carbamic acid ethyl ester


name: 6-Oxo-5,6-dihydro-phenanthridine-3-carboxylic acid methyl ester


phenanthridone

A member of the class of phenanthridines that is phenanthridine with an oxo substituent at position 6. A poly(ADP-ribose) polymerase (PARP) inhibitor, it has been shown to exhibit immunosuppressive activity.


An isoquinolinol that is isoquinoline in which the hydrogens at positions 1 and 5 are replaced by hydroxy groups.


name: 4-Carbamoyl-2-(4-methoxy-phenyl)-benzoimidazole-1-carboxylic acid benzyl ester


name: 5-(6-Oxo-5,6-dihydro-benzo[c][1,5]naphthyridin-2-yl)-2,5-diaza-bicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester


TIPIRACIL HYDROCHLORIDE

A hydrochloride obtained by combining tipiracil with one equivalent of hydrochloric acid. Used in combination with trifluridine, a nucleoside metabolic inhibitor, for treatment of advanced/relapsed unresectable colorectal cancer.


zavegepant

A member of the class of ureas that is urea in which both amino groups are replaced by 4-(2-oxo-1,2-dihydroquinolin-3-yl)piperidin-1-yl and {(2R)-3-(7-methyl-1H-indazol-5-yl)-1-[4-(1-methylpiperidin-4-yl)piperazin-1-yl]-1-oxopropan-2-yl}amino groups. It is a calcitonin gene-related peptide receptor antagonist whose hydrochloride salt has been approved by the FDA for the acute treatment of migraine.


name: Acetic acid 1-(2-dimethylamino-ethyl)-4-(4-methoxy-phenyl)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepin-3-yl ester


name: Oxalyl-aryl-amino benzoic acid-based inhibitor 8f


name: Oxalyl-aryl-amino benzoic acid-based inhibitor 2


name: Oxalyl-aryl-amino benzoic acid-based inhibitor 22


name: Phosphoric acid mono-{(R)-2-((Z)-octadec-9-enoylamino)-3-[4-(pyridin-2-ylmethoxy)-phenyl]-propyl} ester


1-palmitoyl-sn-glycerol 3-phosphate

A 1-acyl-sn-glycerol 3-phosphate having palmitoyl as the acyl group.


name: Phosphoric acid mono-[(R)-3-[4-(1H-indol-2-yloxy)-phenyl]-2-((Z)-octadec-9-enoylamino)-propyl] ester


name: 4-[3-(2-Methoxy-pyridin-3-yl)-pyrazolo[1,5-a]pyrimidin-5-yl]-piperazine-1-carboxylic acid isopropyl ester


name: {(S)-1-[(S)-1-(4-Butoxy-benzyl)-2,3-dioxo-propylcarbamoyl]-2-phenyl-ethyl}-carbamic acid benzyl ester


name: [1-(1-Formyl-2-phenyl-ethylcarbamoyl)-2-phenyl-ethyl]-carbamic acid benzyl ester(Cbz-Phe-Phe-CHO)


name: 3-[3-(2-Benzyloxycarbonylamino-3-phenyl-propionylamino)-2-oxo-4-phenyl-butylsulfanyl]-propionic acid ethyl ester


name: [1-(1-Benzyl-3-tert-butylsulfanyl-2-oxo-propylcarbamoyl)-2-phenyl-ethyl]-carbamic acid benzyl ester


name: {1-[1-Benzyl-2-oxo-3-(3-phenyl-propylsulfanyl)-propylcarbamoyl]-2-phenyl-ethyl}-carbamic acid benzyl ester


name: {1-[1-Benzyl-2-oxo-3-(3-phenyl-propylsulfanyl)-propylcarbamoyl]-3-methyl-butyl}-carbamic acid benzyl ester


name: [1-(1-Benzyl-3-tert-butylsulfanyl-2-oxo-propylcarbamoyl)-3-methyl-butyl]-carbamic acid benzyl ester


name: [1-(3-tert-Butylsulfanyl-2-oxo-1-phenethyl-propylcarbamoyl)-2-phenyl-ethyl]-carbamic acid pyridin-3-ylmethyl ester


name: {(S)-1-[2,5-Dioxo-1-(3-phenyl-propyl)-piperidin-4-ylcarbamoyl]-2-phenyl-ethyl}-carbamic acid benzyl ester


name: [1-(1-Benzyl-3-tert-butylsulfanyl-2-oxo-propylcarbamoyl)-3-methyl-butyl]-carbamic acid pyridin-4-ylmethyl ester


name: [1-(3-tert-Butylsulfanyl-2-oxo-1-phenethyl-propylcarbamoyl)-3-methyl-butyl]-carbamic acid pyridin-3-ylmethyl ester


A diazo compound that is L-phenylalanyl-L-phenylalanine in which the amino group is protected by a (benzyloxy)carbonyl group and the carboxy group is substituted by a diazoacetyl group. It is a cathepsin L inhibitor.


SID 26681509

A carbohydrazide that is L-tryptophan in which the amino and carboxy groups are substituted by tert-butoxycarbonyl and 2-({[2-(2-ethylanilino)-2-oxoethyl]sulfanyl}carbonyl)hydrazinyl groups, respectively. It is a potent and reversible inhibitor of human cathepsin L (IC50 = 56 nM).


name: [(S)-1-((2S,3S)-2-Isobutoxy-4-oxo-azetidin-3-ylcarbamoyl)-2-phenyl-ethyl]-carbamic acid benzyl ester


name: [(S)-1-(2,5-Dioxo-1-phenethyl-piperidin-4-ylcarbamoyl)-2-phenyl-ethyl]-carbamic acid benzyl ester


name: [(S)-1-((S)-1-Benzyl-2-phenylamino-ethylcarbamoyl)-3-methyl-butyl]-carbamic acid benzyl ester


name: [(S)-1-(2,5-Dioxo-1-propyl-piperidin-4-ylcarbamoyl)-2-phenyl-ethyl]-carbamic acid benzyl ester


name: [(S)-1-(1-Isobutyl-2,5-dioxo-piperidin-4-ylcarbamoyl)-2-phenyl-ethyl]-carbamic acid benzyl ester


name: [(S)-1-(1-Benzyl-2,5-dioxo-piperidin-4-ylcarbamoyl)-2-phenyl-ethyl]-carbamic acid benzyl ester


name: [(S)-1-(1-Isopropyl-2,5-dioxo-piperidin-4-ylcarbamoyl)-2-phenyl-ethyl]-carbamic acid benzyl ester


name: [(S)-1-((2S,3S)-2-tert-Butoxy-4-oxo-azetidin-3-ylcarbamoyl)-2-phenyl-ethyl]-carbamic acid benzyl ester


name: {(S)-1-[1-(2-Methoxy-ethyl)-2,5-dioxo-piperidin-4-ylcarbamoyl]-2-phenyl-ethyl}-carbamic acid benzyl ester


name: 3,5-Dimethyl-1-(3-nitrophenyl)-1H-pyrazole-4-carboxylic acid ethyl ester


name: 1-(2-Chlorophenyl)-3,5-dimethyl-1H-pyrazole-4-carboxylic acid ethyl ester


An aromatic amide resulting from the formal condensation of the carboxy group of 8-methoxy-2-(trifluoromethyl)quinoline-5-carboxylic acid with the primary amino group of 3,5-dichloropyridin-4-amine 1-oxide. It is a potent inhibitor of phosphodiesterase IV (PDE4).


name: 2-(1-Hydroxyethyl)-7-methoxypyrazolo[1,5-a]pyridine-4-carboxyl ic acid (3,5-dichloropyridin-4-yl)amide


name: (3S,4R)-4-(3-Cyclopentyloxy-4-methoxy-phenyl)-pyrrolidine-1,3-dicarboxylic acid 1-tert-butyl ester


name: (3S,4R)-3-tert-Butoxycarbonylamino-4-(3-cyclopentyloxy-4-methoxy-phenyl)-pyrrolidine-1-carboxylic acid benzyl ester


name: 2''-Phenylamino-6-piperazin-1-yl[2,4'']bipyridinyl-4-carboxylic Acid Methyl Amide


RADICICOL

An antifungal macrolactone antibiotic, obtained from Diheterospora chlamydosporia and Chaetomium chiversii that inhibits protein tyrosine kinase and heat shock protein 90 (Hsp90).


TANESPIMYCIN

A 19-membered macrocyle that is geldanamycin in which the methoxy substituent attached to the benzoquinone moiety has been replaced by an allylamino group. It is a potent inhibitor of heat shock protein 90 (Hsp90). A less toxic analogue than geldanamycin, it induces apoptosis and displays antitumour effects.


A member of the class of thiadiazoles that is 1,2,3-thiadiazole substituted at positions 4 and 5 by 2,4-dihydroxy-4-chlorophenyl and 4-methoxyphenyl groups respectively.


ONALESPIB

A member of the class of isoindoles that is isoindole in which the amino group has been acylated by a 2,4-dihydroxy-5-isopropylbenzoyl group and in which position 5 of the isoidole moiety has been substituted by a (4-methylpiperazin-1-yl)methyl group. A second-generation Hsp90 inhibitor.


name: Chisomicine D; 8-hydro-(8S*,9S*)-dihydroxy-14,15-en-chisomicine A


An aromatic amide obtained by formal condensation of the carboxy group of 5-(5-chloro-2,4-dihydroxyphenyl)-4-(4-methoxyphenyl)pyrazole-3-carboxylic acid with the amino group of ethylamine.


A member of the class of 1,2-benzoxazoles carrying 2,4-dihydroxy-4-chlorophenyl and (2-morpholin-4-ylethyl)amino substituents at positions 3 and 5 respectively.


DESACETYL SALANNIN

A limonoid that is salannin in which the acetyloxy group at position 6 is replaced by a hydroxy group. It has been isolated from Azadirachta indica.


A member of the class of 6-aminopurines that is 2-fluoroadenine carrying additional 2-chloro-3,4,5-trimethoxybenzyl and pent-4-yn-1-yl substituents at positions 8 and 9 respectively.


ECONAZOLE NITRATE

A racemate composed of equimolar amounts of (R)- and (S)-econazole nitrate. Used to treat skin infections such as athlete's foot, jock itch, ringworm and other fungal skin infections.


A member of the class of pyrazoles that is 1H-pyrazole carrying 1,4-benzodioxane-6-yl and 5-ethyl-2,4-dihydroxyphenyl substituents at positions 4 and 5 respectively.


TRIADIMENOL

A member of the class of triazoles that is 3,3-dimethyl-1-(1,2,4-triazol-1-yl)butane-1,2-diol substituted at position O1 by a 4-chlorophenyl group. A fungicide for cereals, beet and brassicas used to control a range of diseases including powdery mildew, rusts, bunts and smuts.


diiodohydroxyquinoline

A monohydroxyquinoline that is quinolin-8-ol in which the hydrogens at positions 5 and 7 are replaced by iodine.  It is considered the drug of choice for treating asymptomatic or moderate forms of amoebiasis.


ethyl violet

An organic chloride salt that is the monochloride salt of ethyl violet cation. Used for inclusion in mixed dye solutions of the iron resorcin fuchsin type for demonstrating elastic fibres.


octhilinone

A member of the class of 1,2-thiazole that is 1,2-thiazol-3-one substituted on the nitrogen (position 2) by an octyl group. A fungicide and antibacterial agent, it is used for treatment of canker and other fungal and bacterial diseases in fruit trees. It is no longer approved for use within the European Union.


brilliant green

An organic hydrogensulfate salt having 4-{[4-(diethylamino)phenyl](phenyl)methylidene}-N,N-diethylcyclohexa-2,5-dien-1-iminium as the counterion.


nitroxoline

A monohydroxyquinoline in which the hydroxy group is positioned at C-8 with a nitro group trans to it at C-5.


name: 2-Oxo-2H-chromene-3-carboxylic acid 2-methoxy-4-(2-nitro-vinyl)-phenyl ester


CANAGLIFLOZIN

A hydrate that is the hemihydrate form of canagliflozin. Used for treatment of type II diabetes via inhibition of sodium-glucose transport protein subtype 2.


name: US9617250, S-entiomer of Example 22 of D1


name: [(2R)-2-amino-3-oxo-3-(tetradecylamino)propyl] dihydrogen phosphate;2,2,2-trifluoroacetic acid


name: [(1R,2R)-1-(2-Benzyloxycarbonylamino-2-hydroxycarbamoyl-ethylcarbamoyl)-2-methyl-butyl]-carbamic acid benzyl ester


name: [(1R,2R)-1-((R)-1-Hydroxycarbamoyl-2-thiazol-4-yl-ethylcarbamoyl)-2-methyl-butyl]-carbamic acid 2-bromo-benzyl ester


name: [(1R,2R)-1-(2-Benzylamino-2-hydroxycarbamoyl-ethylcarbamoyl)-2-methyl-butyl]-carbamic acid benzyl ester