levoketoconazole

A cis-1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine which dioxolane moiety has (2S,4R)-configuration.


DL-threo-β-hydroxyaspartate

The (3S)-diastereomer of 3-hydroxy-L-aspartic acid.


posaconazole

An N-arylpiperazine that consists of piperazine carrying two 4-substituted phenyl groups at positions 1 and 4. A triazole antifungal drug.


piperaquine

An aminoquinoline that is 1,3-di(piperazin-1-yl)propane in which the nitrogen at position 4 of each of the piperazine moieties is replaced by a 7-chloroquinolin-4-yl group.


(R)-butaconazole

The (R)-enantiomer of butaconazole.


BROMUCONAZOLE

A member of the class of oxolanes carrying 1,2,4-triazol-ylmethyl and 2,4-dichlorophenyl substituents at position 2 as well as a bromo substituent at position 4.  A foliar applied conazole fungicide for a range of crops including cereals, fruit, vegetables and vines.


name: {4-[6-(2-Dimethylamino-1-imidazol-1-yl-propyl)-naphthalen-2-yloxymethyl]-phenoxy}-acetic acid methyl ester


DIHYDROCUBEBIN

A glycol that is butane-1,4-diol substituted at the 2- and 3-positions by (1,3-benzodioxol-5-yl)methyl groups (the R,R-configuration).


name: 3-[6-(2-Dimethylamino-1-imidazol-1-yl-propyl)-naphthalen-2-yloxymethyl]-benzoic acid methyl ester


ELLIPTECINE

A organic heterotetracyclic compound that is pyrido[4,3-b]carbazole carrying two methyl substituents at positions 5 and 11.


(3-aminopropyl)phosphonic acid

A phosphonic acid in which the hydrogen attached to the phosphorus of phosphonic acid is substituted by a 3-aminopropyl group. It is a partial agonist of GABAB receptors.


saquinavir

An aspartic acid derivative obtained by formal condensation of the primary amino group of (2S,3R)-4-[(3S,4aS,8aS)-3-(tert-butylcarbamoyl)octahydroisoquinolin-2(1H)-yl]-3-hydroxy-1-phenylbutan-2-ylamine with the carboxy group of N(2)(-quinolin-2-ylcarbonyl)-L-asparagine. An inhibitor of HIV-1 protease.


dihydroanhydropodorhizol

A member of the class of butan-4-olides carrying 3,4,5-trimethoxybenzyl and (1,3-benzodioxol-5-yl)methyl substituents at positions 3 and 4 respectively.


erythromycin

An erythromycin that consists of erythronolide A having 2,6-dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranosyl and 3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl residues attahced at positions 4 and 6 respectively.


name: 2-Benzoylamino-3-naphthalen-1-yl-acrylic acid allyl ester


(R)-enilconazole

A 1-[2-(allyloxy)-2-(2,4-dichlorophenyl)ethyl]imidazole that is the (R)-enantiomer of enilconazole.


ETACONAZOLE

A member of the class of dioxolanes that is 1,3-dioxolane substituted at position 2 by 2,4-dichlorophenyl and 1,2,4-triazol-1-ylmethyl groups and at position 4 by an ethyl group. An obsolete fungicide that was used to control powdery mildew on fruit and other crops.


name: 2,7,10,12-Tetraazatridecanoic acid, 9-(2-aminoethyl)-12-methyl-13-[2-(1-methylethyl)-4-thiazolyl]-8,11-dioxo-3,6-bis(phenylmethyl)-, 5-thiazolylmethyl ester, (3R,6R,9S)-


abiraterone

A 3beta-sterol that is androsta-5,16-dien-3beta-ol substituted at position 17 by a 3-pyridyl group. Administered as the O-acetate, it is used for treatment of metastatic castrate-resistant prostate cancer.


CIS-UROCANIC ACID

A urocanic acid in which the double bond of the carboxyethene moiety has Z configuration.


(R)-econazole

A 1-{2-(4-chlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl}imidazole that is the (R)-enantiomer of econazole.


SEPIAPTERIN

A sepiapterin with L configuration.


name: Pyrrolidine-1,2-dicarboxylic acid 2-[(benzo[1,3]dioxol-5-ylmethyl)-amide] 1-[(2-methoxy-phenyl)-amide]


HINOKININ

A lignan that is dihydrofuran-2(3H)-one (gamma-butyrolactone) substituted by a 3,4-methylenedioxybenzyl group at positions 3 and 4 (the 3R,4R-diastereoisomer).


name: 1-(4-amino-1,2,5-oxadiazol-3-yl)-5-[(2-pyridinylthio)methyl]-4-triazolecarboxylic acid propan-2-yl ester


name: N-[3-(3-Chloro-phenylcarbamoyl)-phenyl]-succinamic acid methyl ester


isoconazole

A racemate comprising equimolar amounts of (R)- and (S)-isoconazole. A broad-spectrum antibacterial drug used (as its nitrate salt) for treatment of dermatomycoses.


lopinavir

A dicarboxylic acid diamide that is amphetamine is substituted on nitrogen by a (2,6-dimethylphenoxy)acetyl group and on the carbon alpha- to nitrogen by a (1S,3S)-1-hydroxy-3-{[(2S)-3-methyl-2-(2-oxotetrahydropyrimidin-1-yl)butanoyl]amino}-4-phenylbutyl group. An antiretroviral of the protease inhibitor class, it is used against HIV infections as a fixed-dose combination with another protease inhibitor, ritonavir.


nelfinavir

An aryl sulfide that is used (as its mesylate salt) for treatment of HIV and also exhibits some anticancer properties.


name: Nicotinic acid 2-(3,4-dichloro-phenyl)-2-oxo-ethyl ester


A 1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine in which the dioxolane ring has S configuration at positions 2 and 4.


podophyllotoxin

An organic heterotetracyclic compound that has a furonaphthodioxole skeleton bearing a 3,4,5-trimethoxyphenyl substituent. It is found in the roots and rhizomes of Podophyllum species and is used for the topical treatment of genital warts.


sulconazole

A racemate comprising equimolar amounts of (R)- and (S)-sulconazole. An antifungal agent with activity against Candida species, it is used (generally as the nitrate salt) for the topical treatment of fungal skin infections.


mefloquine

A racemate composed of (+)-(11R,2'S)- and (-)-(11S,2'R)-enantiomers of mefloquine. An antimalarial agent which acts as a blood schizonticide; its mechanism of action is unknown.


name: 7-[[2-(3,4-dihydro-1H-isoquinolin-2-yl)-1-oxoethyl]amino]-5H-[1,3]dioxolo[4,5-f]indole-6-carboxylic acid ethyl ester


name: 4-[4-(2,4-Dioxothiazolidin-5-ylidenemethyl)-2-methoxyphenoxy]-naphthalene-1-carboxylic Acid Methyl Ester


(R)-nicardipine

The R-enantiomer of nicardipine.


ARASERTACONAZOLE

A 1-{2-[(7-chloro-1-benzothiophen-3-yl)methoxy]-2-(2,4-dichlorophenyl)ethyl}imidazole that is the active R-enantiomer of sertaconazole and is used (as its nitrate salt) for treatment of vulvovaginal candidiasis. The racemate itself is also used as a broad-spectrum antifungal drug.


L-histidine

The L-enantiomer of the amino acid histidine.


name: 5-(3-Benzo[1,3]dioxol-5-yl-acryloylamino)-isophthalic acid dimethyl ester


bifonazole

A racemate comprising equimolar amounts of R- and S-bifonazole. It is a broad spectrum antifungal drug used for the treatment of fungal skin and nail infections.


name: 3-[2-(4-{3-[4-(3-Methoxy-benzyl)-piperazine-1-carbonyl]-adamantan-1-yl}-phenoxy)-acetylamino]-benzoic acid methyl ester


A 1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine in which the dioxolane ring has R configuration at positions 2 and 4.


name: (4-Chloro-phenyl)-carbamic acid 2-{5-[(2-chloro-phenyl)-morpholin-4-yl-methyl]-tetrazol-1-yl}-ethyl ester


name: 4-Nitro-benzoic acid 2-methoxy-4-[(pyridine-4-carbonyl)-hydrazonomethyl]-phenyl ester


name: But-2-enedioic acid (cyclopentylcarbamoyl-o-tolyl-methyl)-(4-ethoxy-phenyl)-amide (5-methyl-isoxazol-3-yl)-amide


PHENYLHYDRAZINE

A phenylhydrazine that is the monophenyl derivative of hydrazine.


(S)-nicardipine

The S-enantiomer of nicardipine.


FIPRONIL

A racemate comprising equimolar amounts of (R)- and (S)-fipronil.


A 1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol that is the R-enantiomer of SKF 38393.


SCH 23390

A benzazepine that is 2,3,4,5-tetrahydro-3-benzazepine bearing a phenyl substituent at position 1, a methyl substituent at position 3, a chloro substituent at position 7 and a hydroxy substituent at position 8.


DICLOFENAC SODIUM

The sodium salt of diclofenac.


name: 4-(5-Amino-3-furan-2-yl-pyrazol-1-yl)-benzoic acid methyl ester


SULINDAC SULFIDE

An  aryl sulfide that is a metabolite of  sulindac. A non-steroidal anti-inflammatory drug, which also has anticancer activity.


TROLOX

A chromanol that is 6-hydroxychromane which is substituted by a carboxy group at position 2 and by methyl groups at positions 2, 5, 7, and 8. A cell-permeable, water-soluble analogue of vitamin E, it is used as a standard for measuring the antioxidant capacity of complex mixtures.


MIROPROFEN

A monocarboxylic acid that is propionic acid in which one of the hydrogens at position 2 is substituted by a 4-(imidazo[1,2-a]pyridin-2-yl)phenyl group. A non-steroidal anti-inflammatory drug that also exhibits analgesic, antipyretic and platelet aggregation inhibition properties.


phenothiazine

The 10H-tautomer of phenothiazine.


A monocarboxylic acid that is propionic acid in which one of the hydrogens at position 2 is substituted by a 4-[(2-hydroxycyclopentyl)methyl]phenyl group (the 2S,1'R,2'S-stereoisomer. The active metabolite of loxoprofen.


name: 4-Chloro-5-(4-chloro-phenyl)-1-(4-sulfamoyl-phenyl)-1H-pyrazole-3-carboxylic acid methyl ester


name: 2-(3-Benzoyl-phenyl)-propionic acid 2-nitrooxy-ethyl ester


name: 2-[4-(Thiophene-2-carbonyl)-phenyl]-propionic acid 2,3-bis-nitrooxy-propyl ester


name: 2-[4-(Thiophene-2-carbonyl)-phenyl]-propionic acid 2-nitrooxy-propyl ester


name: 2-[4-(Thiophene-2-carbonyl)-phenyl]-propionic acid 2-nitrooxy-ethyl ester


name: 2-(3-Benzoyl-phenyl)-propionic acid 2,3-bis-nitrooxy-propyl ester


name: 2-(3-Benzoyl-phenyl)-propionic acid 2-nitrooxy-propyl ester


A salicylanilide derivative with chloride substituents at C-3 and C-5 of the salicylate moiety and at C-3 and C-4 of the anilide moiety.


pterostilbene

A stilbenol that consists of trans-stilbene bearing a hydroxy group at position 4 as well as two methoxy substituents at positions 3' and 5'.


gamma-mangostin

A member of the class of xanthones that is 9H-xanthene substituted by hydroxy group at positions 1, 3, 6 and 7, an oxo group at position 9 and prenyl groups at positions 2 and 8. Isolated from the stems of Cratoxylum cochinchinense, it exhibits antitumour activity.


CAFFEIC ACID PHENETHYL ESTER

An alkyl caffeate ester in which 2-phenylethyl is the alkyl component.


name: 4-(4-(Aminosulfonyl)phenyl)-5-(4-fluorophenyl)thiophene-2-carboxylic acid methyl ester


A member of the class of monomethoxyflavones that is 3'-methoxyflavone bearing an additional amino substituent at position 2'.


name: 6-(3-tert-Butyl-ureido)-2-(2-methoxy-5-nitro-benzylsulfanyl)-3-propyl-3H-benzoimidazole-4-carboxylic acid methyl ester


A secondary carboxamide resulting from the formal condensation of the carboxy group of {4-[1-(trifluoromethyl)cyclopropyl]phenyl}acetic acid with the amino group of 6-[(3-amino-1H-pyrazol-1-yl)methyl]pyridine-3-carbonitrile. It is a selective, orally available T-type calcium channel blocker that is being studied as a potential new treatment in epilepsy.


SOPHORAFLAVANONE G

A tetrahydroxyflavanone having a structure of naringenin bearing an additional hydroxyl substituent at position 2' as well as a (2R)-5-methyl-2-(prop-1-en-2-yl)hex-4-en-1-yl (lavandulyl) substituent at position 8'.


sophoraflavanone B

A trihydroxyflavanone that is (S)-naringenin having a prenyl group at position 8.


NNC 55-0396 dihydrochloride

The dihydrochloride salt of NNC 55-0396. It is a stable analogue of mibefradil and a highly selective T-type calcium channel blocker.


CURCUMIN PYRAZOLE

A pyrazole obtained by cyclocodensation of the two carbonyl groups of curcumin with hydrazine.


PHENOXAZINE

A member of the class of phenoxazines that is morpholine which is ortho-fused to two benzene rings at positions 2-3 and 5-6.


nordihydroguiaretic acid

A tetrol that is butane which is substituted at positions 2 and 3 by 3,4-dihydroxybenzyl groups. Masoprocol, the meso-form found in the leaves of the creosote bush (Larrea divaricata), is a potent lipoxygenase inhibitor.


name: (E)-3-(10H-Phenoxazin-2-yl)-acrylic acid ethyl ester


NYMPHAEOL A

A tetrahydroxyflavanone that is (2S)-flavanone substituted by hydroxy group at positions 5, 7, 3' and 4' and a geranyl group at position 6. Isolated from Macaranga tanarius and propolis collected in Okinawa, it exhibits radical scavenging activity.


Embelin

A member of the class of dihydroxy-1,4-benzoquinones that is 2,5-dihydroxy-1,4-benzoquinone which is substituted by an undecyl group at position 3. Isolated from Lysimachia punctata and Embelia ribes, it exhibits antimicrobial, antineoplastic and inhibitory activity towards hepatitis C protease.


name: 3 inverted exclamation marka-Omethyl-5 inverted exclamation marka-hydroxydiplacone


name: 10H-Phenoxazine-2-carboxylic acid methyl ester


name: 7-[3-(4-Hydroxy-tetrahydro-pyran-4-yl)-benzyloxy]-4-phenyl-naphthalene-2-carboxylic acid methyl ester


tepoxalin

A hydroxamic acid obtained by formal condensation of the carboxy group of 3-[5-(4-chlorophenyl)-1-(4-methoxyphenyl)pyrazol-3-yl]propanoic acid with the amino group of N-methylhydroxylamine. It is used in veterinary medicine for the control of pain and inflammation caused by musculoskeletal disorders such as hip dysplasia and arthritis in dogs.


BW B70C

A  hydroxamic acid that is urea in which both the hydrogens attached to one of the nitrogens are replaced by a hydroxy and a (1E)-1-[3-(4-fluorophenoxy)phenyl]but-1-en-3-yl group. A selective inhibitor of arachidonate 5-lipoxygenase, it can be used for the treatment of asthma.


name: (R)-2-[3-Fluoro-5-(1-methyl-2-oxo-1,2-dihydro-quinolin-6-ylmethoxy)-phenyl]-2-methoxy-butyric acid methyl ester


name: 4-{3-Fluoro-5-[4-(2-methyl-imidazol-1-yl)-benzyloxy]-phenyl}-tetrahydro-pyran-4-carboxylic acid ethyl ester


name: (R)-2-[3-Fluoro-5-(naphthalen-2-ylmethoxy)-phenyl]-2-methoxy-butyric acid methyl ester


TAIWANIN C

A furonaphthodioxole that is furo[3',4':6,7]naphtho[2,3-d][1,3]dioxol-6(8H)-one substituted by a 1,3-benzodioxol-5-yl group at position 5. It is a naturally occurring lignan extracted from Taiwania cryptomerioides and found to be a potential inhibitor of COX2 expression.


name: (S)-2-[3-Fluoro-5-(naphthalen-2-ylmethoxy)-phenyl]-2-methoxy-butyric acid methyl ester


name: (S)-2-[3-Fluoro-5-(1-methyl-2-oxo-1,2-dihydro-quinolin-6-ylmethoxy)-phenyl]-2-methoxy-butyric acid methyl ester


name: Acetic acid 2,5-diphenyl-thiazol-4-yl ester


name: 4-[Hydroxy-(4-phenyl-butyryl)-amino]-butyric acid ethyl ester


A member of the class of biindoles that is indirubin substituted at position 6 by a bromo group and in which the keto group at position 3' has undergone condensation with hydroxylamine to form the corresponding oxime.


A member of the class of monohydroxy-1,4-benzoquinones that is embelin in which the hydroxy group at position 5 is replaced by a methoxy group. Isolated from Lysimachia punctata and Embelia ribes, it exhibits antileishmanial activity as well as inhibitory activity towards hepatitis C protease.


name: 10H-Phenoxazine-1-carboxylic acid methyl ester


TETRAC

A monocarboxylic acid that is thyroacetic acid carrying four iodo substituents at positions 3, 3', 5 and 5'.


name: Hexadecanoic acid (S)-2-benzyloxycarbonyl-2-(2-tetradecanoylamino-acetylamino)-ethyl ester


name: (S)-3-Hydroxy-2-(2-tetradecanoylamino-acetylamino)-propionic acid benzyl ester


name: 1-Ethyl-4-phenyl-1,2,5,6-tetrahydro-pyridine-3-carboxylic acid nonyl ester


name: 1-(3,4-Dichloro-phenyl)-cyclohexanecarboxylic acid 2-diethylamino-ethoxymethyl ester


name: 1-Ethyl-4-phenyl-1,2,3,6-tetrahydro-pyridine-3-carboxylic acid nonyl ester


name: 1-(3,4-Dichloro-phenyl)-cyclohexanecarboxylic acid 2-pyrrolidin-1-yl-ethoxymethyl ester


name: 1-(4-Chloro-phenyl)-cyclopentanecarboxylic acid 2-(2-diethylamino-ethoxy)-ethyl ester


mosapramine

A racemate comprising equimolar amounts of (R)- and (S)-mosapramine. It is a second-generation antipsychotic used for the treatment of schizophrenia.


name: (S)-1-{2-[4-(4-Chloro-benzyl)-piperazin-1-yl]-acetyl}-2,3-dihydro-1H-indole-2-carboxylic acid methyl ester


name: (S)-1-{2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-acetyl}-2,3-dihydro-1H-indole-2-carboxylic acid methyl ester


A benzamide resulting from the formal condensation of the carboxy group of 4-(dimethylamino)benzoic acid with the amino group of 7-amino-N-hydroxyheptanamide. It is a potent inhibitor of histone deacetylases and induces cell cycle arrest and apoptosis in several human cancer cell lines.


A benzodioxine that is idazoxan substituted at position 2 by a methoxy group.


idazoxan

A benzodioxine that is 2,3-dihydro-1,4-benzodioxine in which one of the hydrogens at position 2 has been replaced by a 4,5-dihydro-1H-imidazol-2-yl group.


emetine

A pyridoisoquinoline comprising emetam having methoxy substituents at the 6'-, 7'-, 10- and 11-positions. It is an antiprotozoal agent and emetic. It inhibits SARS-CoV2, Zika and Ebola virus replication and displays antimalarial, antineoplastic and antiamoebic properties.


vancomycin

A complex glycopeptide from Streptomyces orientalis. It inhibits a specific step in the synthesis of the peptidoglycan layer in the Gram-positive bacteria Staphylococcus aureus and Clostridium difficile.


TCDD

Any dibenzodioxine in which two or more hydrogens have been replaced by chlorines.


A hydrochloride salt obtained by reaction of 6-({7-[(1-aminocyclopropyl)methoxy]-6-methoxyquinolin-4-yl}oxy)-N-methyl-1-naphthamide with one equivalent of hydrochloric acid. E-3810 is a dual VEGFR and FGFR inhibitor


name: 4-{2-[4-(1-Butyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)-phenoxy]-acetyl}-piperazine-1-carboxylic acid benzyl ester


NECA

A derivative of adenosine in which the 5'-hydroxymethyl group is replaced by an N-ethylcarboxamido group.


name: [4-(2,6-Dioxo-1-propyl-2,3,6,7-tetrahydro-1H-purin-8-yl)-phenoxy]-acetic acid methyl ester


name: 4-{2-[4-(2,6-Dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)-phenoxy]-acetylamino}-benzoic acid methyl ester


name: 4-{2-[4-(1-Butyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)-phenoxy]-acetylamino}-benzoic acid methyl ester


name: 4-(2,6-Dioxo-1-propyl-2,3,6,7-tetrahydro-1H-purin-8-yl)-benzenesulfonic acid 4-nitro-phenyl ester


name: 4-{2-[4-(1-Butyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)-phenoxy]-acetyl}-piperazine-1-carboxylic acid ethyl ester


name: [4-(2,6-Dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)-phenoxy]-acetic acid 2,5-dioxo-pyrrolidin-1-yl ester


name: 4-(2,6-Dioxo-1-propyl-2,3,6,7-tetrahydro-1H-purin-8-yl)-benzenesulfonic acid 3-nitro-phenyl ester


name: 4-(1-Butyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)-benzenesulfonic acid 3-nitro-phenyl ester


name: 4-(1-Butyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)-benzenesulfonic acid 4-nitro-phenyl ester


name: 3-[4-(2,6-Dioxo-1-propyl-2,3,6,7-tetrahydro-1H-purin-8-yl)-phenyl]-acrylic acid methyl ester


name: Amino-8-propyl-2-(2-furyl) pyrazolo (4,3-e)-1,2,4-triazolo (1,5-c)pyrimidine


name: 4-Furan-3-yl-6-methyl-2-oxo-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid ethyl ester


A derivative of adenosine in which the 5'-hydroxymethyl group is replaced by N-ethylcarboxamido and the hydrogen at position 2 on the adenine is replaced by a 4-(2-carboxyethyl)phenethylamino group.


name: 4-(2,6-Dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)-benzenesulfonic acid 3-nitro-phenyl ester


name: 4-Amino-5-chloro-2-methoxy-benzoic acid 2-[4-(3-methoxy-phenyl)-piperazin-1-yl]-ethyl ester


name: Potassium salt of  4-(2,6-dioxo-1-propyl-2,3,6,7-tetrahydro-1H-purin-8-yl)-benzenesulfonate (PSB-1115)


levisoprenaline

An optically active phenylethanolamine compound having an isopropyl substituent attached to the nitrogen atom.


name: Methanesulfonic acid 3-{(R)-2-[(R)-2-hydroxy-2-(3-prop-2-ynylamino-phenyl)-ethylamino]-propyl}-1H-indol-7-yl ester


name: Methanesulfonic acid 3-{(R)-2-[(R)-2-(3-but-2-enylamino-phenyl)-2-hydroxy-ethylamino]-propyl}-1H-indol-7-yl ester


A benzimidazole that is benzimidazol-2-one substituted at position 4 by a 3-(tert-butylamino)-2-hydroxypropoxy group.


name: Methanesulfonic acid (R)-3-{2-[(R)-2-(3-benzenesulfonylamino-phenyl)-2-hydroxy-ethylamino]-propyl}-1H-indol-7-yl ester


OLODATEROL HYDROCHLORIDE

A hydrochloride obtained by combining olodaterol with one equivalent of hydrochloric acid. Used for long-term treatment of airflow obstruction in patients with chronic obstructive pulmonary disease including chronic bronchitis and/or emphysema.


clenbuterol

A substituted aniline that is 2,6-dichloroaniline in which the hydrogen at position 4 has been replaced by a 2-(tert-butylamino)-1-hydroxyethyl group.


FENPROPIMORPH

A racemate comprising equimolar amounts of (R)- and (S)-fenpropimorph. It is a systemic fungicide, used to control a variety of fungal diseases in cereal crops.


name: {4-Oxo-4-[4-(3-phenyl-propyl)-piperazin-1-yl]-butyl}-carbamic acid tert-butyl ester


A 17-oxo steroid that is dehydroepiandrosterone in which the hydroxy group at position 3beta is replaced by a 2-(diethylamino)ethoxy group. It is a cholesterol biosynthesis inhibitor and induces cataracts in rats.


An aromatic ether that is (2-phenoxyethyl)benzene which carries a 2-(dipropylamino)ethyl group at position 3 and a methoxy group at position 6. It is a potent and selective sigma1 receptor antagonist.


eperisone

A racemate that is an equimolar mixture of (R)- and (S)-eperisone. It is used (as the hydrochloride salt) as a muscle relaxant for the symptomatic treatment of muscle spasm and spasticity.


name: Benzeneacetic acid, 3,4-dichloro-, 2-(1-pyrrolidinyl)ethyl ester


An N-alkylpiperazine that consists of piperazine bearing 2-(benzhydryloxy)ethyl and 3-phenylpropyl groups at positions 1 and 4 respectively. Potent and selective inhibitor of dopamine uptake (KD = 5.5 nM in rat striatal membranes).


bromhexine

A substituted aniline that is 2,4-dibromoaniline which is substituted at position 6 by a [cyclohexyl(methyl)amino]methyl group. It is used (as the monohydrochloride salt) as a mucolytic for the treatment of respiratory disorders associated with productive cough (i.e. a cough characterised by the production of sputum).


pramocaine

A member of the class of morpholines that is morpholine substituted at the nitrogen atom by a 3-(4-butoxyphenoxy)propyl group.


An organic heterotricyclic compound that is metazocine in which the methyl group at the N-position is replaced by an allyl group.


HYDANTOIN

An imidazolidinone with oxo groups at position 2 and 4.


name: {3-Oxo-3-[4-(3-phenyl-propyl)-piperazin-1-yl]-propyl}-carbamic acid tert-butyl ester


name: 1-[6-(4-Oxo-2-phenyl-4H-chromen-6-yloxy)-hexyl]-piperidine-4-carboxylic acid ethyl ester


name: 1-[6-(4-Oxo-2-phenyl-4H-chromen-6-yloxy)-hexyl]-piperidine-3-carboxylic acid ethyl ester


name: {2-Oxo-2-[4-(3-phenyl-propyl)-piperazin-1-yl]-ethyl}-carbamic acid tert-butyl ester


CINANSERIN

An aryl sulfide that is (2E)-3-phenyl-N-(2-sulfanylphenyl)prop-2-enamide in which the hydrogen of the thiol group is substituted by a 3-(dimethylamino)propyl group. It is a 5-hydroxytryptamine receptor antagonist and an inhibitor of SARS-CoV replication.


TERCONAZOLE

A 1-(4-{[2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)-4-isopropylpiperazine in which positions 2 and 4 of the 1,3-dioxolane moiety have R and S configuration, respectively.


dexfenfluramine

The S-enantiomer of fenfluramine. It stimulates the release of serotonin and selectively inhibits its reuptake, but unlike fenfluramine it does not possess catecholamine agonist activity. It was formerly given by mouth as the hydrochloride in the treatment of obesity, but, like fenfluramine, was withdrawn wolrdwide following reports of valvular heart defects.


name: 2-(4-Fluoro-phenyl)-5-[4-(5-fluoro-pyrimidin-2-yl)-piperazin-1-yl]-pentanoic acid methyl ester


terbinafine

A tertiary amine that is N-methyl-1-naphthalenemethylamine in which the amino hydrogen is replaced by a 3-(tertbutylethynyl)allyl group. An antifungal agent administered orally (generally as the hydrochloride salt) for the treatment of skin and nail infections.


Guanidine carrying a phenyl substituent on each of the two amino groups. It is used as an accelerator in the rubber industry.


name: 4-[4,4-Bis-(4-fluoro-phenyl)-butyl]-piperazine-1-carboxylic acid 2-(4-cyano-phenyl)-ethyl ester


naftifine

A tertiary amine in which the nitrogen is substituted by methyl, alpha-naphthylmethyl, and (1E)-cinnamyl groups. It is used (usually as its hydrochloride salt) for the treatment of fungal skin infections.


METHYSERGIDE

A synthetic ergot alkaloid, structurally related to the oxytocic agent methylergonovine and to the potent hallucinogen LSD and used prophylactically to reduce the frequency and intensity of severe vascular headaches.


CINACALCET HYDROCHLORIDE

A hydrochloride derived from equimolar amounts of cinacalcet and hydrogen chloride.


name: [2-(2,2,2-Trifluoro-1-hydroxy-1-trifluoromethyl-ethyl)-naphthalen-1-yl]-carbamic acid isopropyl ester


name: 1-[2-(3-Benzyloxycarbonyl-phenyl)-acetyl]-3-(4-hydroxy-benzyl)-4-oxo-azetidine-2-carboxylic acid benzyl ester


name: Nonanoic acid 3-(2-dimethylamino-ethyl)-1H-indol-5-yl ester


name: Trifluoromethanesulfonic acid 3-(2-aminoethyl)-1H-indol-5-yl ester


name: Trifluoro-methanesulfonic acid 3-(2-dimethylamino-ethyl)-1H-indol-5-yl ester


name: Trifluoro-methanesulfonic acid 3-(2-diethylamino-ethyl)-1H-indol-5-yl ester


name: Isobutyric acid 3-(2-dimethylamino-ethyl)-1H-indol-5-yl ester


name: Propionic acid 3-(2-dimethylamino-ethyl)-1H-indol-5-yl ester


name: 2,2-Dimethyl-propionic acid 3-(2-dimethylamino-ethyl)-1H-indol-5-yl ester


name: Trifluoro-methanesulfonic acid 3-(2-dipropylamino-ethyl)-1H-indol-5-yl ester


N-methylquipazine

An aminoquinoline that consists of quinoline in which the hydrogen at position 2 is substituted by a 4-methylpiperazin-1-yl group. A 5-HT3 agonist. Has almost the same affinity for 5-HT3 sites as quipazine but unlike the latter, does not bind to 5-HT1B sites.


name: 3-Ethyl-2-oxo-2,3-dihydro-benzoimidazole-1-carboxylic acid (8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl)-amide; hydrochloride


name: 4-Desmethyl 3-Methyl Vortioxetine Hydrochloride


name: 3-(4-Fluorophenyl)-1-methyl-5-(1-piperazinyl)-4-(4-pyridinyl)-1H-pyrrole-2-carboxylic acid methyl ester


glyceraldehyde

An aldotriose comprising propanal having hydroxy groups at the 2- and 3-positions. It plays role in the formation of advanced glycation end-products (AGEs), a deleterious accompaniment to ageing.


3,5-di-O-caffeoyl quinic acid

A carboxylic ester that is the diester obtained by the condensation of the hydroxy groups at positions 3 and 5 of (-)-quinic acid with the carboxy group of trans-caffeic acid. Isolated from Brazilian propolis and Suaeda glauca, it exhibits hepatoprotective and cytotoxic activities.


QUERCITRIN

A quercetin O-glycoside that is quercetin substituted by a alpha-L-rhamnosyl moiety at position 3 via a glycosidic linkage.


ellagic acid

An organic heterotetracyclic compound resulting from the formal dimerisation of gallic acid by oxidative aromatic coupling with intramolecular lactonisation of both carboxylic acid groups of the resulting biaryl. It is found in many fruits and vegetables, including raspberries, strawberries, cranberries, and pomegranates.


chlorogenic acid

A cinnamate ester obtained by formal condensation of the carboxy group of trans-caffeic acid with the 3-hydroxy group of quinic acid. It is an intermediate metabolite in the biosynthesis of lignin.


ISOLIQUIRITIGENIN

A member of the class of chalcones that is trans-chalcone hydroxylated at C-2', -4 and -4'.


ISOLIQUIRITIN

A monosaccharide derivative that is trans-chalcone substituted by hydroxy groups at positions 2' and 4' and a beta-D-glucopyranosyloxy group at position 4 respectively.


name: 3-[(R)-2-Amino-2-((S)-1-benzyl-2-carboxy-ethylcarbamoyl)-propyl]-indole-1-carboxylic acid adamantan-2-yl ester


name: 1-[2-Oxo-2-(3,4,5-trimethoxy-phenyl)-acetyl]-piperidine-2-carboxylic acid 4-phenyl-1-(3-pyridin-3-yl-propyl)-butyl ester


name: 1-[2-Oxo-2-(3,4,5-trimethoxy-phenyl)-acetyl]-piperidine-2-carboxylic acid 4-phenyl-1-(3-phenyl-propyl)-butyl ester


name: 1-[2-Oxo-2-(3,4,5-trimethoxy-phenyl)-acetyl]-piperidine-2-carboxylic acid 1-(3-phenyl-propyl)-4-pyridin-2-yl-butyl ester


ASCOMYCIN

A macrolide that is produced by the fermentation of Streptomyces hygroscopicus and exhibits strong immunosuppressant properties.


name: 1-(3,3-Dimethyl-2-oxo-butyryl)-piperidine-2-carboxylic acid 3-phenyl-propyl ester


name: 1-[2-Oxo-2-(3,4,5-trimethoxy-phenyl)-acetyl]-piperidine-2-carboxylic acid 4-phenyl-1-(2-pyridin-3-yl-ethyl)-butyl ester


name: 1-(2-Oxo-2-phenyl-acetyl)-piperidine-2-carboxylic acid 4-phenyl-1-(3-phenyl-propyl)-butyl ester


name: 1-(3,3-Dimethyl-2-oxo-butyryl)-pyrrolidine-2-carboxylic acid 3-pyridin-3-yl-propyl ester


name: 1-(3,3-Dimethyl-2-oxo-butyryl)-piperidine-2-carboxylic acid 4-phenyl-1-(3-phenyl-propyl)-butyl ester


name: 1-(3,3-Dimethyl-2-oxo-pentanoyl)-piperidine-2-carboxylic acid 3,3-diphenyl-propyl ester


name: 1-(3,3-Dimethyl-2-oxo-pentanoyl)-pyrrolidine-2-carbothioic acid S-(3-pyridin-3-yl-propyl) ester


name: 1-(2-Cyclohexyl-2-oxo-acetyl)-pyrrolidine-2-carboxylic acid 3-pyridin-3-yl-propyl ester


name: 1-(Adamantan-1-ylcarbamoyl)-piperidine-2-carboxylic acid 3-(2,4-dimethoxy-phenyl)-propyl ester


name: 1-(3,3-Dimethyl-2-oxo-pentanoyl)-piperidine-2-carboxylic acid 3-(2,5-dimethoxy-phenyl)-propyl ester


name: 1-(3,3-Dimethyl-2-oxo-pentanoyl)-pyrrolidine-2-carbothioic acid S-phenethyl ester


name: 1-[2-Oxo-2-(3,4,5-trimethoxy-phenyl)-acetyl]-piperidine-2-carboxylic acid 4-(4-methoxy-phenyl)-butyl ester


name: 1-(3,3-Dimethyl-2-oxo-pentanoyl)-piperidine-2-carboxylic acid 1-ethyl-2-(4-methoxy-phenyl)-4-phenyl-butyl ester


name: 1-[2-Oxo-2-(3,4,5-trimethoxy-phenyl)-acetyl]-piperidine-2-carboxylic acid 3-(1H-indol-3-yl)-propyl ester


name: 1-(3,3-Dimethyl-2-oxo-pentanoyl)-piperidine-2-carboxylic acid (R)-1,3-diphenyl-propyl ester


name: 1-[2-Oxo-2-(3,4,5-trimethoxy-phenyl)-acetyl]-piperidine-2-carboxylic acid 3-phenoxy-benzyl ester


name: 1-(3,3-Dimethyl-2-oxo-pentanoyl)-piperidine-2-carboxylic acid 1-phenethyl-3-phenyl-propyl ester


name: (S)-1-Phenylmethanesulfonyl-pyrrolidine-2-carboxylic acid 3-(4-methoxy-phenyl)-propyl ester


name: 1-(3,3-Dimethyl-2-oxo-butyryl)-piperidine-2-carboxylic acid 4-(4-methoxy-phenyl)-butyl ester


name: 1-(3,3-Dimethyl-2-oxo-pentanoyl)-piperidine-2-carboxylic acid 3-(3,4,5-trimethoxy-phenyl)-propyl ester


name: 1-(3,3-Dimethyl-2-oxo-pentanoyl)-piperidine-2-carboxylic acid 4-phenyl-1-(3-phenyl-propyl)-butyl ester


name: 1-(Adamantan-1-ylcarbamoyl)-piperidine-2-carboxylic acid 3-(3,4-dimethoxy-phenyl)-propyl ester


name: 1-(3,3-Dimethyl-2-oxo-butyryl)-piperidine-2-carboxylic acid 3-cyclohexyl-propyl ester


name: 1-Phenylmethanesulfonyl-piperidine-2-carboxylic acid 4-phenyl-butyl ester


name: 1-[2-Oxo-2-(3,4,5-trimethoxy-phenyl)-acetyl]-piperidine-2-carboxylic acid 4-cyclohexyl-butyl ester


name: 1-(3,3-Dimethyl-2-oxo-pentanoyl)-pyrrolidine-2-carboxylic acid 3-phenyl-propyl ester


name: (S)-1-(3,3-Dimethyl-2-oxo-pentanoyl)-pyrrolidine-2-carboxylic acid 3-phenyl-propyl ester


name: 1-Phenylmethanesulfonyl-piperidine-2-carboxylic acid 3-(3,4-dimethoxy-phenyl)-propyl ester


name: 1-(2-Oxo-2-phenyl-acetyl)-piperidine-2-carboxylic acid 1-(3-phenyl-propyl)-4-pyridin-2-yl-butyl ester


name: (S)-1-(3,3-Dimethyl-2-oxo-pentanoyl)-pyrrolidine-2-carboxylic acid (R)-1,3-diphenyl-propyl ester


name: 1-(3,3-Dimethyl-2-oxo-pentanoyl)-piperidine-2-carboxylic acid 4-(4-methoxy-phenyl)-butyl ester


name: 1-(2-Methyl-butylcarbamoyl)-piperidine-2-carboxylic acid 3-pyridin-3-yl-propyl ester


name: 1-Phenylmethanesulfonyl-pyrrolidine-2-carboxylic acid 3-pyridin-3-yl-propyl ester


name: 1-(2-Cyclohexyl-2-oxo-acetyl)-pyrrolidine-2-carboxylic acid 3-phenyl-propyl ester


name: (S)-1-Cyclohexylthiocarbamoyl-pyrrolidine-2-carboxylic acid 3-(3,4-dimethoxy-phenyl)-propyl ester


name: 1-Phenylmethanesulfonyl-piperidine-2-carboxylic acid 3-(4-methoxy-phenyl)-propyl ester


name: 1-(2-Phenyl-propionyl)-piperidine-2-carboxylic acid 1-(3-carboxymethoxy-phenyl)-3-(3,4-dimethoxy-phenyl)-propyl ester


name: 1-(3,3-Dimethyl-2-oxo-butyryl)-pyrrolidine-2-carboxylic acid 3-phenyl-propyl ester


name: 1-(2-Cyclohexyl-2-oxo-acetyl)-piperidine-2-carboxylic acid 4-(4-methoxy-phenyl)-butyl ester


name: 1-Phenylmethanesulfonyl-piperidine-2-carboxylic acid 1-benzyl-4-phenyl-butyl ester


name: (S)-1-(3,3-Dimethyl-2-oxo-pentanoyl)-piperidine-2-carboxylic acid 3-phenyl-propyl ester


name: 1-(Adamantan-2-ylthiocarbamoyl)-pyrrolidine-2-carboxylic acid 3-pyridin-3-yl-propyl ester


name: 1-Phenylmethanesulfonyl-piperidine-2-carboxylic acid 3-(3,5-dimethoxy-phenyl)-propyl ester


name: 1-(3,3-Dimethyl-2-oxo-pentanoyl)-pyrrolidine-2-carboxylic acid 2-(3,4,5-trimethoxy-phenyl)-ethyl ester


name: 1-(3,3-Dimethyl-2-oxo-pentanoyl)-piperidine-2-carboxylic acid 3-pyridin-3-yl-propyl ester


name: (S)-1-(3,3-Dimethyl-2-oxo-pentanoyl)-piperidine-2-carboxylic acid 3-pyridin-3-yl-propyl ester


name: 1-Cyclohexylthiocarbamoyl-pyrrolidine-2-carboxylic acid 3-pyridin-3-yl-propyl ester


name: 1-(2-Phenyl-butyryl)-piperidine-2-carboxylic acid 1-(3-carboxymethoxy-phenyl)-3-(3,4-dimethoxy-phenyl)-propyl ester


name: 1-(3,3-Dimethyl-2-oxo-pentanoyl)-piperidine-2-carboxylic acid 3-cyclohexyl-propyl ester


name: 1-Benzenesulfonyl-piperidine-2-carboxylic acid 3-(3,4-dimethoxy-phenyl)-propyl ester


name: 1-(3,3-Dimethyl-2-oxo-pentanoyl)-pyrrolidine-2-carboxylic acid 3-pyridin-2-yl-propyl ester


name: 1-(3,3-Dimethyl-2-oxo-pentanoyl)-pyrrolidine-2-carboxylic acid 3-cyclohexyl-propyl ester


name: 1-(2-Cyclohexyl-2-oxo-acetyl)-piperidine-2-carboxylic acid 3-phenyl-propyl ester


name: (S)-1-[2-((1S,2R,5R)-1-Hydroxy-5-isopropyl-2-methyl-cyclohexyl)-2-oxo-acetyl]-piperidine-2-carboxylic acid benzyl ester


name: 1-(Toluene-4-sulfonyl)-piperidine-2-carboxylic acid 3-(4-methoxy-phenyl)-propyl ester


name: 1-(3,3-Dimethyl-2-oxo-pentanoyl)-pyrrolidine-2-carboxylic acid 3-(2,5-dimethoxy-phenyl)-propyl ester


name: 1-Benzenesulfonyl-piperidine-2-carboxylic acid 3-(4-methoxy-phenyl)-propyl ester


name: 1-Diphenylacetyl-piperidine-2-carboxylic acid 1-(3-carboxymethoxy-phenyl)-3-(3,4-dimethoxy-phenyl)-propyl ester


name: 1-Phenylmethanesulfonyl-piperidine-2-carboxylic acid 3-(4-fluoro-phenyl)-propyl ester


name: 1-(Toluene-4-sulfonyl)-piperidine-2-carboxylic acid 4-phenyl-1-(3-phenyl-propyl)-butyl ester


name: 1-(Toluene-4-sulfonyl)-piperidine-2-carboxylic acid 3-(3,5-dimethoxy-phenyl)-propyl ester


name: 1-Phenylmethanesulfonyl-piperidine-2-carboxylic acid 3-(4-chloro-phenyl)-propyl ester


name: 1-(3,3-Dimethyl-2-oxo-pentanoyl)-pyrrolidine-2-carboxylic acid (E)-3-(2,5-dimethoxy-phenyl)-allyl ester


name: (S)-1-(Adamantan-1-ylcarbamoyl)-pyrrolidine-2-carboxylic acid 4-phenyl-butyl ester


name: 1-Benzenesulfonyl-piperidine-2-carboxylic acid 4-phenyl-butyl ester


name: 1-Benzenesulfonyl-piperidine-2-carboxylic acid 3-(3,5-dimethoxy-phenyl)-propyl ester


name: 1-(Toluene-4-sulfonyl)-piperidine-2-carboxylic acid 4-phenyl-butyl ester


name: 1-(2-Oxo-2-phenyl-acetyl)-piperidine-2-carboxylic acid 3-pyridin-3-yl-propyl ester


name: 1-Benzenesulfonyl-piperidine-2-carboxylic acid 3-(4-fluoro-phenyl)-propyl ester


name: 1-(1,1-Dimethyl-propylcarbamoyl)-pyrrolidine-2-carboxylic acid 3-pyridin-3-yl-propyl ester


name: 1-(2-Cyclohexyl-2-oxo-acetyl)-piperidine-2-carboxylic acid 3-cyclohexyl-propyl ester


name: (S)-1-Phenylcarbamoyl-pyrrolidine-2-carboxylic acid 3-phenyl-propyl ester


name: (S)-1-(Adamantan-1-ylthiocarbamoyl)-pyrrolidine-2-carboxylic acid 3-(4-fluoro-phenyl)-propyl ester


name: (S)-1-(Adamantan-1-ylcarbamoyl)-pyrrolidine-2-carboxylic acid 3-phenyl-propyl ester


Ro 25-6981

A member of the class of piperidines that is 4-benzylpiperidine substituted by a 3-hydroxy-3-(4-hydroxyphenyl)-2-methylpropyl group at position 1 (the 1R,2S-stereoisomer). It is a potent antagonist of the GluN2B subunit of the N-methyl-D-aspartate (NMDA) receptor.


ELIPRODIL

A member of the class of piperidines that is piperidine substituted by a 2-(4-chlorophenyl)-2-hydroxyethyl group at position 1 and by a 4-fluorobenzyl group at position 4.


A member of the class of pyrazoles that is 1-(2-hydroxyethyl)pyrazole carrying additional 4-pyridyl and 1-(hydroxyimino)indan-5-yl substituents at positions 3 and 4 respectively.


A member of the class of benzothiazoles that is 1,3-benzothiazole substituted by (cyclopropanecarbonyl)amino, 4-fluoro-3-{2-[3-(trifluoromethyl)phenyl]acetamido}phenoxy, and cyano groups at positions 2, 6 and 7, respectively. It is a potent pan-RAF inhibitor with IC50 of 1.4, 2.4 and 8.3 nM for CRAF, BRAF(V600E), BRAF(WT), respectively.


An N-{5-[2-{4-[2-(dimethylamino)ethoxy]phenyl}-4-(pyridin-4-yl)-1H-imidazol-5-yl]-2,3-dihydro-1H-inden-1-ylidene}hydroxylamine in which the oxime group has E configuration.


AMASTATIN

A tetrapeptide comprising (2S,3R)-3-amino-2-hydroxy-5-methylhexanoyl, L-valyl, L-valyl and L-aspartic acid units joined in sequence


COFORMYCIN

An N-glycosyl in which (8R)-3,6,7,8-tetrahydroimidazo[4,5-d][1,3]diazepin-8-ol is attached to ribofuranose via a beta-N(3)-glycosidic bond. compound The parent of the class of coformycins.


EHNA

EHNA of absolute configuration 2R,3S. Selective inhibitor of cGMP-stimulated phosphodiesterase (PDE2) (IC50 = 0.8 - 4 mM). Also a potent inhibitor of adenosine deaminase.


(+)-EHNA

EHNA of absolute configuration 2S,3R.


name: 3-[4-((Z)-2-Iodo-vinyl)-phenyl]-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester


name: 3-[4-((Z)-2-Bromo-vinyl)-phenyl]-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester


name: 3-[4-((Z)-2-Bromo-vinyl)-phenyl]-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester


name: 3-[4-(2,2-Dibromo-vinyl)-phenyl]-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester


name: 3beta-(4-Methylthiophenyl)nortropane-2beta-carboxylic acid methyl ester


name: 3-(4-Iodo-phenyl)-6-methyl-6-aza-bicyclo[3.2.2]nonane-4-carboxylic acid methyl ester


MDMA

A member of the class of  benzodioxoles that is 1,3-benzodioxole substituted by a 2-(methylamino)propyl group at position 5.


name: 3-(3,4-Dichloro-phenyl)-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester


name: 3beta-(4-Ethylthiophenyl)nortropane-2beta-carboxylic acid methyl ester


name: 3-[4-(2,2-Dibromo-vinyl)-phenyl]-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester


name: 3-(3,4-Dichloro-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester


A fluoroindole that is 1H-indole in which the hydrogens at positions 3 and 6 are replaced by 1-[2-(2,2-dioxo-5,6-dihydro-4H-2lambda(6)-[1,2,5]thiadiazolo[4,3,2-ij]quinolin-1(2H)-yl)ethyl]-1,2,3,6-tetrahydropyridin-4-yl and fluoro groups, respectively. It is an inhibitor of the 5-hydroxytryptamine transporter (Ki = 2.3 nM) and an antagonist of 5-hydroxytryptamine(2A) receptor (Ki = 0.81 nM).


name: (1R,3S)-3-(4-iodophenyl)-8-methyl-8-azabicyclo[3.2.1]octane-4-carboxylic acid methyl ester


name: 3beta-(3-Bromo-4-methylsulfinylphenyl)tropane-2beta-carboxylic acid methyl ester


name: 3beta-(4-Methylsulfinylphenyl)tropane-2beta-carboxylic acid methyl ester


name: 3beta-(4-Methoxyphenyl)tropane-2beta-carboxylic acid methyl ester


name: 3-(3,4-Dichloro-phenyl)-8-oxa-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester


name: 3beta-(4-Methylthiophenyl)-8-allylnortropane-2beta-carboxylic acid methyl ester


name: 7-Hydroxy-8-methyl-3-naphthalen-2-yl-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester


name: 3beta-(4-Methylthiophenyl)-8-propylnortropane-2beta-carboxylic acid methyl ester


name: 3-(4-Chloro-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester


name: 8-Methyl-3-naphthalen-2-yl-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester


name: Dimethyl-carbamic acid (R)-2-methyl-1-[2-(4-nitro-phenoxy)-ethyl]-2,3-dihydro-1H-benzo[c]azepin-7-yl ester


primaquine

An N-substituted diamine that is pentane-1,4-diamine substituted by a 6-methoxyquinolin-8-yl group at the N(4) position. It is a drug used in the treatment of malaria and Pneumocystis pneumonia.


name: 3-(3-Iodo-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester


name: 3-(4-Iodo-phenyl)-8-oxa-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester


An oxime O-ether that is the (E)-O-(2-aminoethyl)oxime derived from 4'-iodo-5-methoxyvalerophenone.


name: (S)-3-[Bis-(4-fluoro-phenyl)-methoxy]-8-(3-phenyl-propyl)-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester


name: (2R,3S)-3-[Bis-(4-fluoro-phenyl)-methoxy]-8-(3-phenyl-propyl)-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester


name: 3-(3,4-Dimethoxy-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester


name: 8-Methyl-3-p-tolyl-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester


name: 3-(3,4-Dichloro-phenyl)-7-hydroxy-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester


name: 3-(4-Bromo-phenyl)-8-oxa-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester


name: 3-(3,4-Dichloro-phenyl)-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester


name: 6-Hydroxy-8-methyl-3-naphthalen-2-yl-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester


name: 3-Biphenyl-3-yl-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester


name: 3beta-(4-Ethylthiophenyl)-8-allylnortropane-2beta-carboxylic acid methyl ester


name: 3beta-(4-Ethylthiophenyl)-8-propylnortropane-2beta-carboxylic acid methyl ester


name: 3-(4-Fluoro-phenyl)-8-(5-phenyl-pentyl)-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester


name: 3-(3-Furan-2-yl-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester


name: 8-Methyl-3-(3-thiophen-3-yl-phenyl)-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester


COCAINE HYDROCHLORIDE

The hydrochloride salt of cocaine. It is a local anesthetic and vasoconstrictor and is clinically used for that purpose, particularly in the eye, ear, nose, and throat. It also has powerful central nervous system effects similar to the amphetamines and is a drug of abuse.


name: 3-(3,4-Dichloro-phenyl)-7-hydroxy-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid ethyl ester


name: 3-(4-Chloro-phenyl)-8-oxa-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester


name: 3-Naphthalen-2-yl-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester


name: 8-Methyl-3-naphthalen-2-yl-8-aza-bicyclo[3.2.1]oct-2-ene-2-carboxylic acid methyl ester


MEPHEDRONE

An aromatic ketone that is propiophenone substituted at C-4 and at C-beta with methyl and methylamino groups respectively. It is a synthetic stimulant and entactogen drug of the amphetamine and cathinone classes.


name: 3-(4-Fluoro-phenyl)-8-(3-phenyl-propyl)-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester


name: 3-(3,4-Dichloro-phenyl)-6-hydroxy-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester


name: 3-(3,4-Diacetyl-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester


(R)-CITALOPRAM

A 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile that has R-configuration at the chiral centre. It is the inactive enantiomer of citalopram.


name: 3beta-(4-Methylsulfonylphenyl)tropane-2beta-carboxylic acid methyl ester


name: 6-Hydroxy-8-methyl-3-naphthalen-2-yl-8-aza-bicyclo[3.2.1]oct-2-ene-2-carboxylic acid methyl ester


name: 3-(3,4-Dihydroxy-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester


name: (2-Methylsulfanyl-benzyl)-(S)-pyrrolidin-3-yl-carbamic acid ethyl ester


name: 3-(4-Chloro-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid phenyl ester


name: Biphenyl-2-ylmethyl-(R)-pyrrolidin-3-yl-carbamic acid ethyl ester


name: 3-(4-Chloro-phenyl)-6-methyl-6-aza-bicyclo[3.2.2]nonane-4-carboxylic acid isopropyl ester


name: (S)-Pyrrolidin-3-yl-(2-trifluoromethyl-benzyl)-carbamic acid ethyl ester


name: (2-Phenoxy-benzyl)-(S)-pyrrolidin-3-yl-carbamic acid ethyl ester


name: (S)-3-[Bis-(4-fluoro-phenyl)-methoxy]-8-(5-phenyl-pentyl)-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester


name: (2R,3S)-3-[Bis-(4-fluoro-phenyl)-methoxy]-8-(5-phenyl-pentyl)-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester


name: 7-Hydroxy-8-methyl-3-naphthalen-2-yl-8-aza-bicyclo[3.2.1]oct-2-ene-2-carboxylic acid methyl ester


name: (2-Isopropyl-benzyl)-(S)-pyrrolidin-3-yl-carbamic acid ethyl ester


butenafine

Trimethylamine in which hydrogen atoms attached to different methyl groups are substituted by 1-naphthyl and 4-tert-butylphenyl groups. It is an inhibitor of squalene epoxidase, an enzyme responsible for the creation of sterols needed in fungal cell membranes, and is used as its hydrochloride salt for treatment of dermatological fungal infections.


name: Biphenyl-2-ylmethyl-(S)-pyrrolidin-3-yl-carbamic acid isopropyl ester


(R)-nomifensine

The R enantiomer of nomifensine.


name: 3-(3,4-Dichloro-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]oct-2-ene-2-carboxylic acid methyl ester


(S)-nomifensine

The S enantiomer of nomifensine.


telatinib

A member of the class of furopyridazines that is furo[2,3-d]pyridazine substituted by (4-chlorophenyl)amino and [2-(methylcarbamoyl)pyridin-4-yl]methoxy groups at positions 4 and 7, respectively. It is a potent inhibitor of VEGFR2/3, c-Kit and PDGFRalpha.


name: acetic acid, methoxy-, 2-(1H-indol-2-ylcarbonyl)-1H-indol-5-yl ester


A secondary amino compound consisting of two molecules of tacrine that are linked together through their exocyclic amino groups by a heptane-1,7-diyl chain. Bis(7)-tacrine is an acetylcholinesterase (AChE)inhibitor (IC50 0.40 nM, >1,000 times more potent than tacrine). It has also been found to protect against H2O2 -induced apoptosis in rat pheochromocytoma cells.


name: Benzyl-carbamic acid 1-[(3-fluoro-pyridin-4-yl)-propyl-amino]-3-methyl-1H-indol-5-yl ester


name: Methyl-carbamic acid 1-[(3-fluoro-pyridin-4-yl)-propyl-amino]-3-methyl-1H-indol-5-yl ester


name: 1,12-Di(2-Isoquinoliniumyl)Dodecane With Dibromide Ions


name: 1,9-Di(2-Isoquinoliniumyl)Nonane With Dibromide Ions


name: 1,9-Di(1-Quinoliniumyl)Nonane With Dibromide Ions


name: 2-(4-Dimethylcarbamoyloxy-phenyl)-2-(4-hydroxy-phenyl)-propionic acid 2-diethylamino-ethyl ester


HOOKERIANAMIDE J

A steroid alkaloid that is 5alpha-preg-16-ene substituted by a hydroxy group at position 4, a N,N-dimethylamino group at position 20 and a N-senecoylamino group at position 3 (the 3beta,4beta,20S stereoisomer). Isolated from Sarcococca hookeriana, it exhibits antileishmanial and antibacterial activities.


name: Butyl-carbamic acid 1-[(3-fluoro-pyridin-4-yl)-propyl-amino]-3-methyl-1H-indol-5-yl ester


METHOCTRAMINE HYDROCHLORIDE

A hydrochloride obtained by combining methoctramine with four molar equivalents of hydrochloric acid.


A 4-methyl-L-glutamic acid in which the methyl group at position 4 adopts R-configuration.


name: 3-Isoquinolinecarboxylic acid, 6-(((2S)-2-carboxy-4,4-difluoro-1-pyrrolidinyl)methyl)decahydro-, (3S,4aR,6S,8aR)-


4-methylene-L-glutamic acid

The L-enantiomer of 4-methyleneglutamic acid.


name: (3S,4aS,6S,8aR)-6-[2-(1H-Tetrazol-5-yl)-phenoxy]-decahydro-isoquinoline-3-carboxylic acid isobutyl ester


name: 2-{[3-(4-Chloro-3-methyl-isoxazol-5-ylsulfamoyl)-thiophene-2-carbonyl]-amino}-5-methyl-benzoic acid methyl ester


ENRASENTAN

A member of the class of indanes that is 2,3-dihydro-1H-indene which is substituted by a 1,3-benzodioxol-5-yl group, carboxy group, 2-(2-hydroxyethoxy)-4-methoxyphenyl group and a propoxy group at positions 1S, 2R, 3S and 5, respectively. It is an orally active mixed endothelin A/B receptor antagonist with a 100-fold greater affinity for the endothelin A receptor. The drug was being developed by GSK for the treatment of congestive heart failure and pulmonary hypertension (clinical trials discontinued).


name: 4-((4-(carboxymethyl) cyclohexyl) thio)-1-((6-chloro-1,3-benzodioxol-5-yl) methyl)-2-propyl-1H-imidazole-5-carboxylic acid


name: 2-Methyl-5-(3-oxazol-5-yl-phenylsulfamoyl)-furan-3-carboxylic acid methyl ester


name: 3-(4-Chloro-3-methyl-isoxazol-5-ylsulfamoyl)-thiophene-2-carboxylic acid benzo[1,3]dioxol-5-yl ester


name: 3-[4-Benzo[1,3]dioxol-5-yl-2-hydroxy-2-(4-methoxy-phenyl)-5-oxo-2,5-dihydro-furan-3-ylmethyl]-benzoic acid methyl ester


name: 3-(4-Bromo-3-methyl-isoxazol-5-ylsulfamoyl)-thiophene-2-carboxylic acid p-tolyl ester


name: 4-[4-Benzo[1,3]dioxol-5-yl-2-hydroxy-2-(4-methoxy-phenyl)-5-oxo-2,5-dihydro-furan-3-ylmethyl]-benzoic acid methyl ester


name: [3-(4-Bromo-3-methyl-isoxazol-5-ylsulfamoyl)-thiophen-2-yl]-carbamic acid benzo[1,3]dioxol-5-yl ester


name: 2-{[3-(4-methoxy-phenyl)-1-(3-trifluoromethyl-benzyl)-1H-indole-2-carbonyl]-sulfamoyl}-benzoic acid methyl ester


name: 1-oxo-3-phenyl-6-(3-phenylpropoxy)-1H-indene-2-carboxylic acid ethyl ester


name: Acetic acid 2-[2-amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-propionyl]-1,2,3,4-tetrahydro-isoquinolin-3-ylmethyl ester


carfentanil

A monocarboxylic acid amide resulting from the formal condensation of the aryl amino group of methyl 4-anilino-1-(2-phenylethyl)piperidine-4-carboxylate with propanoic acid.


name: N-cyclohexylmethyl-N-{2-[3-endo-(3-hydroxyphenyl)-8-aza-bicyclo[3.2.1]oct-8-yl]ethyl}succinamic acid methyl ester


name: acetic acid(benzyl-{2-[3-endo-(3-hydroxyphenyl)-8-azabicyclo[3.2.1]oct-8-yl]-ethyl}carbamoyl)methyl ester trifluoroacetate salt


name: N-{2-[3-endo-(3-carbamoyl-phenyl)-8-aza-bicyclo[3.2.1]oct-8-yl]ethyl}-N-cyclohexylmethyl-succinamic acid methyl ester


name: 4-(Carboxy-phenyl-methoxy)-3-methyl-5-propyl-benzoic acid methyl ester


name: 4-(Carboxy-phenyl-methoxy)-3-chloro-5-propyl-benzoic acid methyl ester


name: Benzenepropanoic acid, alpha-ethyl-4-methoxy-3-((((4-(trifluoromethyl)phenyl)methyl)amino)carbonyl)-, (alphaS)-


name: 4-(Carboxy-phenyl-methoxy)-3,5-dipropyl-benzoic acid methyl ester


name: 2-{4-[2-(1,2,3,4-Tetrahydro-quinolin-7-yloxy)-ethoxy]-benzyl}-malonic acid monomethyl ester


OXYPURINOL

A  pyrazolopyrimidine that is 4,5,6,7-tetrahydro-H-pyrazolo[3,4-d]pyrimidine substituted by oxo groups at positions 4 and 6.


name: N-(5-Carbamoyl-3H-imidazol-4-yl)-oxalamic acid hexyl ester


apigenin

A trihydroxyflavone that is flavone substituted by hydroxy groups at positions 4', 5 and 7.  It induces autophagy in leukaemia cells.


DAIDZIN

A glycosyloxyisoflavone that is  daidzein attached to a beta-D-glucopyranosyl residue at position 7 via a glycosidic linkage. It is used in the treatment of alcohol dependency (antidipsotropic).


name: [3-(4-Hydroxy-phenyl)-4-oxo-4H-chromen-7-yloxy]-acetic acid ethyl ester


WIN 18446

A carboxamide that is 1,8-diaminooctane in which a hydrogen attached to each of the amino groups has been replaced by a dichloroacetyl group. Inhibitor of aldehyde dehydrogenase 1a2 (ALDH1a2). Inhibits the biosynthesis of retinoic acid from retinol in neonatal and adult murine testis. It down-regulates sex related genes in zebrafish.


name: 5-[3-(4-Hydroxy-phenyl)-4-oxo-4H-chromen-7-yloxy]-pentanoic acid ethyl ester


name: 6-[3-(4-Hydroxy-phenyl)-4-oxo-4H-chromen-7-yloxy]-hexanoic acid ethyl ester


name: 2-[3-(4-Hydroxy-phenyl)-4-oxo-4H-chromen-7-yloxy]-propionic acid ethyl ester


A organic heterotetracyclic compound that is ellipticine in which the hydrogen at position 9 has been replaced by a hydroxy group.


name: Allyl-{1-[(S)-(benzenesulfonyl-methyl-amino)-methyl-phenyl-butyl]-piperidin-4-yl}-carbamic acid, 4-nitro-benzyl ester


name: {1-[(S)-(Benzenesulfonyl-methyl-amino)-phenyl-butyl]-piperidin-4-yl}-propyl-carbamic acid, 4-nitro-benzyl ester


name: {1-[(S)-4-(Benzenesulfonyl-methyl-amino)-3-phenyl-butyl]-piperidin-4-yl}-propyl-carbamic acid 2-methyl-benzyl ester


name: Carbamic acid, [1-[3-(3-chlorophenyl)-4-[(4R)-4-(1H-indol-3-ylmethyl)-2,5-dioxo-1-imidazolidinyl]butyl]-4-piperidinyl]ethyl-, phenylmethyl ester


name: Carbamic acid, [1-[[(3S,4S)-1-(cyclopentylcarbonyl)-4-phenyl-3-pyrrolidinyl]methyl]-4-piperidinyl]ethyl-, phenylmethyl ester


name: Carbamic acid, [1-[(3S)-3-(3-chlorophenyl)-4-[methyl(phenylsulfonyl)amino]butyl]-4-piperidinyl]ethyl-, phenylmethyl ester


name: {1-[(S)-4-(Benzenesulfonyl-methyl-amino)-3-phenyl-butyl]-piperidin-4-yl}-propyl-carbamic acid benzyl ester


name: 1H-Pyrrolo[3,2-c]pyridine-1-carboxylic acid, octahydro-5-[3-methyl-4-[methyl(phenylsulfonyl)amino]-3-phenylbutyl]-, (4-nitrophenyl)methyl ester


name: {1-[(S)-4-(Benzenesulfonyl-methyl-amino)-3-phenyl-butyl]-piperidin-4-yl}-propyl-carbamic acid 3-methyl-benzyl ester


name: {1-[(S)-4-(Benzenesulfonyl-methyl-amino)-3-phenyl-butyl]-piperidin-4-yl}-propyl-carbamic acid 4-methyl-benzyl ester


name: Carbamic acid, ethyl[1-[4-[(4R)-4-(1H-indol-3-ylmethyl)-2,5-dioxo-1-imidazolidinyl]-3-methyl-3-phenylbutyl]-4-piperidinyl]-, phenylmethyl ester


name: [1-((3S,4S)-1-Cyclohexanecarbonyl-4-phenyl-pyrrolidin-3-ylmethyl)-piperidin-4-yl]-ethyl-carbamic acid benzyl ester


name: Ethyl-{1-[(3S,4S)-1-(naphthalene-1-carbonyl)-4-phenyl-pyrrolidin-3-ylmethyl]-piperidin-4-yl}-carbamic acid benzyl ester


name: Carbamic acid, [1-[(3S)-3-(3-chlorophenyl)-4-[methyl(phenylsulfonyl)amino]butyl]-4-piperidinyl]propyl-, phenylmethyl ester


name: Benzoic acid (S)-2-(3,4-dichloro-phenyl)-4-(spiro[1-benzothiophene-3,4''-piperidinyl])butyl ester


name: Carbamic acid, [1-[4-[(4R)-4-(1H-indol-3-ylmethyl)-2,5-dioxo-1-imidazolidinyl]-3-methyl-3-phenylbutyl]-4-piperidinyl]2-propenyl-, phenylmethyl ester


name: Carbamic acid, [1-[[(3S,4S)-1-benzoyl-4-phenyl-3-pyrrolidinyl]methyl]-4-piperidinyl]ethyl-, phenylmethyl ester


name: {1-[(S)-4-(Benzenesulfonyl-methyl-amino)-3-phenyl-butyl]-piperidin-4-yl}-butyl-carbamic acid benzyl ester


name: {1-[(S)-4-(Benzenesulfonyl-methyl-amino)-3-phenyl-butyl]-piperidin-4-yl}-methyl-carbamic acid benzyl ester


name: {1-[(S)-4-(Benzenesulfonyl-methyl-amino)-3-phenyl-butyl]-piperidin-4-yl}-cyclohexylmethyl-carbamic acid methyl ester


name: 4-[3-(4-{Ethyl-[2-(4-methanesulfonyl-phenyl)-acetyl]-amino}-piperidin-1-yl)-1-phenyl-propyl]-benzoic acid methyl ester


name: [1-((3S,4S)-1-Benzyl-4-phenyl-pyrrolidin-3-ylmethyl)-piperidin-4-yl]-ethyl-carbamic acid benzyl ester


name: {1-[(S)-4-(Benzenesulfonyl-methyl-amino)-3-phenyl-butyl]-piperidin-4-yl}-ethyl-carbamic acid phenyl ester


name: {1-[(S)-4-(Benzenesulfonyl-methyl-amino)-3-phenyl-butyl]-piperidin-4-yl}-hexyl-carbamic acid methyl ester


name: {1-[(S)-4-(Benzenesulfonyl-methyl-amino)-3-phenyl-butyl]-piperidin-4-yl}-ethyl-carbamic acid cyclohexylmethyl ester


name: {1-[(S)-4-(Benzenesulfonyl-methyl-amino)-3-phenyl-butyl]-piperidin-4-yl}-butyl-carbamic acid methyl ester


name: {1-[(S)-4-(Benzenesulfonyl-methyl-amino)-3-phenyl-butyl]-piperidin-4-yl}-propyl-carbamic acid methyl ester


name: {1-[(S)-4-(Benzenesulfonyl-methyl-amino)-3-phenyl-butyl]-piperidin-4-yl}-cyclopentylmethyl-carbamic acid methyl ester


name: Cyclohexyl-{3-[4-hydroxy-4-(3-phenyl-propyl)-piperidin-1-ylmethyl]-4-phenyl-pyrrolidin-1-yl}-acetic acid benzyl ester


name: {1-[(S)-4-(Benzenesulfonyl-methyl-amino)-3-phenyl-butyl]-piperidin-4-yl}-ethyl-carbamic acid tert-butyl ester


name: [1-((3S,4S)-1-Benzoyl-4-phenyl-pyrrolidin-3-ylmethyl)-piperidin-4-yl]-cyclopentylmethyl-carbamic acid methyl ester


name: Carbamic acid, [1-[3-(3-chlorophenyl)-4-[(4R)-4-(1H-indol-3-ylmethyl)-2,5-dioxo-1-imidazolidinyl]-3-methylbutyl]-4-piperidinyl]2-propenyl-, phenylmethyl ester


name: {1-[(S)-4-(Benzenesulfonyl-methyl-amino)-3-phenyl-butyl]-piperidin-4-yl}-cyclohexylmethyl-carbamic acid ethyl ester


name: {1-[(S)-4-(Benzenesulfonyl-methyl-amino)-3-phenyl-butyl]-piperidin-4-yl}-ethyl-carbamic acid ethyl ester


name: {1-[(S)-4-(Benzenesulfonyl-methyl-amino)-3-phenyl-butyl]-piperidin-4-yl}-ethyl-carbamic acid methyl ester


name: [1-((3S,4S)-1-Benzyl-4-phenyl-pyrrolidin-3-ylmethyl)-piperidin-4-yl]-cyclopentylmethyl-carbamic acid methyl ester


name: Carbamic acid, [1-[3-(3-chlorophenyl)-4-[(4R)-4-(1H-indol-3-ylmethyl)-2,5-dioxo-1-imidazolidinyl]-3-methylbutyl]-4-piperidinyl]ethyl-, phenylmethyl ester


name: {1-[(S)-4-(Benzenesulfonyl-methyl-amino)-3-phenyl-butyl]-piperidin-4-yl}-benzyl-carbamic acid methyl ester


name: 2,6-Dimethyl-4-(2-methylsulfanyl-3-nitro-phenyl)-1,4-dihydro-pyridine-3,5-dicarboxylic acid diethyl ester


name: 2,6-Dimethyl-4-(5-methyl-3-phenyl-isoxazol-4-yl)-1,4-dihydro-pyridine-3,5-dicarboxylic acid diethyl ester


name: (S)-2,6-Dimethyl-5-nitro-4-(2-trifluoromethyl-phenyl)-1,4-dihydro-pyridine-3-carboxylic acid methyl ester


name: 1,4-Dihydro-6-methyl-2-(methylthio)-4-(3-nitrophenyl)-5-pyrimidinecarboxylic acid, ethyl ester


name: 2,6-Dimethyl-4-(3-methyl-5-phenethyl-isoxazol-4-yl)-1,4-dihydro-pyridine-3,5-dicarboxylic acid diethyl ester


name: 4-(3,5-Dimethyl-isoxazol-4-yl)-2,6-dimethyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid diethyl ester


name: 6-Methyl-2-methylsulfanyl-4-(2-methylsulfanyl-3-nitro-phenyl)-1,4-dihydro-pyrimidine-5-carboxylic acid methyl ester


name: 4-(5-Ethyl-3-methyl-isoxazol-4-yl)-2,6-dimethyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid diethyl ester


name: 2,6-Dimethyl-4-(5-phenethyl-3-phenyl-isoxazol-4-yl)-1,4-dihydro-pyridine-3,5-dicarboxylic acid diethyl ester


name: 2,6-Dimethyl-4-(5-pentyl-3-phenyl-isoxazol-4-yl)-1,4-dihydro-pyridine-3,5-dicarboxylic acid diethyl ester


name: 2,6-Dimethyl-4-(2-methylsulfanyl-5-nitro-phenyl)-1,4-dihydro-pyridine-3,5-dicarboxylic acid diethyl ester


name: 1,4-Dihydro-2-methoxy-6-methyl-4-(3-nitrophenyl)-5-pyrimidinecarboxylic acid, ethyl ester


name: 4-(3,5-Dimethyl-isoxazol-4-yl)-2,6-dimethyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid dimethyl ester


name: 4-Methyl-2-(3-nitro-phenyl)-2,5-dihydro-benzo[b][1,4]thiazepine-3-carboxylic acid methyl ester


name: 4-(5-Isopropyl-3-phenyl-isoxazol-4-yl)-2,6-dimethyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid diethyl ester


name: 5-(2-Dimethylamino-ethyl)-4-methyl-2-(3-nitro-phenyl)-2,5-dihydro-benzo[b][1,4]thiazepine-3-carboxylic acid methyl ester


name: 9,11-Dimethyl-8-thia-10-aza-tricyclo[7.3.1.0*2,7*]trideca-2(7),3,5,11-tetraene-12,13-dicarboxylic acid diethyl ester


L-ascorbic acid

The L-enantiomer of ascorbic acid and conjugate acid of L-ascorbate.


BENZOTHIAZYL DISULFIDE

An organic disulfide resulting from the formal oxidative coupling of the thiol groups of two molecules of 1,3-benzothiazole-2-thiol. It is used as an accelerator in the rubber industry.


An N-acylpyrrolidine obtained by formal condenstion of the carboxy group of L-proline and the secondary amino group of (R)-pyrrolidine-2-carboxylic acid.


name: [5-Amino-1-((R)-4-cyano-thiazolidine-3-carbonyl)-pentyl]-carbamic acid benzyl ester


An  organochlorine compound that is 7H-purin-2-amine substituted by a chloro group at position 6.


name: [4-((S)-1-Amino-2-oxo-2-thiazolidin-3-yl-ethyl)-cyclohexyl]-carbamic acid naphthalen-1-ylmethyl ester


name: [4-((S)-1-Amino-2-oxo-2-thiazolidin-3-yl-ethyl)-cyclohexyl]-carbamic acid naphthalen-2-ylmethyl ester


A triazolopyrazine that is a rigid cyclohexylamine analogue of sitagliptin.


name: tert-Butyl-carbamic acid 3-[2-(2-cyano-pyrrolidin-1-yl)-2-oxo-ethylamino]-adamantan-1-yl ester


name: [4-((S)-1-Amino-2-oxo-2-thiazolidin-3-yl-ethyl)-cyclohexyl]-carbamic acid benzyl ester


name: {4-[(S)-1-Amino-2-(3,3-difluoro-pyrrolidin-1-yl)-2-oxo-ethyl]-cyclohexyl}-carbamic acid benzyl ester


name: [4-((S)-1-Amino-2-oxo-2-thiazolidin-3-yl-ethyl)-cyclohexyl]-carbamic acid 3,4-dichloro-benzyl ester


name: {4-[(S)-1-Amino-2-((S)-3-fluoro-pyrrolidin-1-yl)-2-oxo-ethyl]-cyclohexyl}-carbamic acid benzyl ester


name: Phenyl-carbamic acid 3-[2-(2-cyano-pyrrolidin-1-yl)-2-oxo-ethylamino]-adamantan-1-yl ester


vidarabine

A purine nucleoside in which adenine is attached to arabinofuranose via a beta-N(9)-glycosidic bond.


name: Cyclohexyl-carbamic acid 3-[2-(2-cyano-pyrrolidin-1-yl)-2-oxo-ethylamino]-adamantan-1-yl ester


name: Acetic acid 3-[2-(2-cyano-pyrrolidin-1-yl)-2-oxo-ethylamino]-adamantan-1-yl ester


name: (4-Methoxy-phenyl)-carbamic acid (1R,3S)-3-((S)-1-amino-2-oxo-2-thiazolidin-3-yl-ethyl)-cyclohexyl ester


name: {4-[(S)-1-Amino-2-((R)-3-fluoro-pyrrolidin-1-yl)-2-oxo-ethyl]-cyclohexyl}-carbamic acid benzyl ester


name: [4-((S)-1-Amino-2-oxo-2-pyrrolidin-1-yl-ethyl)-cyclohexyl]-carbamic acid benzyl ester


name: (4-Iodo-phenyl)-carbamic acid (1R,3S)-3-((S)-1-amino-2-oxo-2-pyrrolidin-1-yl-ethyl)-cyclohexyl ester


name: (4-Iodo-phenyl)-carbamic acid (1R,3R)-3-((S)-1-amino-2-oxo-2-pyrrolidin-1-yl-ethyl)-cyclopentyl ester


An N-acylpyrrolidine that is the pyrrolidine amide of (2S,3S)-2-amino-3-{3-[4-(methylsulfonyl)phenyl]-1,2,4-oxadiazol-5-yl}butanoic acid.


name: (4-Methoxy-phenyl)-carbamic acid 3-[2-(2-cyano-pyrrolidin-1-yl)-2-oxo-ethylamino]-adamantan-1-yl ester


name: (4-Methoxy-phenyl)-carbamic acid (1R,3S)-3-((S)-1-amino-2-oxo-2-pyrrolidin-1-yl-ethyl)-cyclohexyl ester


name: (4-Iodo-phenyl)-carbamic acid (1S,3S)-3-((S)-1-amino-2-oxo-2-pyrrolidin-1-yl-ethyl)-cyclopentyl ester


name: Diisopropyl-carbamic acid 3-[2-(2-cyano-pyrrolidin-1-yl)-2-oxo-ethylamino]-adamantan-1-yl ester


name: (3-Fluoro-phenyl)-carbamic acid (1R,3S)-3-((S)-1-amino-2-oxo-2-thiazolidin-3-yl-ethyl)-cyclopentyl ester


name: (4-Methoxy-phenyl)-carbamic acid (1R,3S)-3-((S)-1-amino-2-oxo-2-thiazolidin-3-yl-ethyl)-cyclopentyl ester


name: (4-Methoxy-phenyl)-carbamic acid (1S,3S)-3-((S)-1-amino-2-oxo-2-pyrrolidin-1-yl-ethyl)-cyclopentyl ester


name: (3,4-Dichloro-phenyl)-carbamic acid (1R,3S)-3-((S)-1-amino-2-oxo-2-thiazolidin-3-yl-ethyl)-cyclopentyl ester


name: (3S)-1-[(2S,3S)-2-Amino-3-(4-fluorophenyl)-1-oxobutanyl]-3-fluoropyrrolidine trifluoroacetic acid salt


name: (4-Iodo-phenyl)-carbamic acid (1S,3S)-3-((S)-1-amino-2-oxo-2-pyrrolidin-1-yl-ethyl)-cyclohexyl ester


name: {4-[(S)-1-Amino-2-((3R,4R)-3,4-difluoro-pyrrolidin-1-yl)-2-oxo-ethyl]-cyclohexyl}-carbamic acid benzyl ester


name: (4-Methoxy-phenyl)-carbamic acid (1S,3S)-3-((S)-1-amino-2-oxo-2-thiazolidin-3-yl-ethyl)-cyclohexyl ester


KUROMANIN

An anthocyanin cation that is a cyanidin cation linked to a beta-D-glucosyl moiety at position 3.


name: (4-Methoxy-phenyl)-carbamic acid (1S,3S)-3-((S)-1-amino-2-oxo-2-pyrrolidin-1-yl-ethyl)-cyclohexyl ester


name: (4-Iodo-phenyl)-carbamic acid (1R,3S)-3-((S)-1-amino-2-oxo-2-pyrrolidin-1-yl-ethyl)-cyclopentyl ester


name: (4-Iodo-phenyl)-carbamic acid (1S,3R)-3-((S)-1-amino-2-oxo-2-pyrrolidin-1-yl-ethyl)-cyclopentyl ester


name: {4-[(S)-1-Amino-2-((3S,4S)-3,4-difluoro-pyrrolidin-1-yl)-2-oxo-ethyl]-cyclohexyl}-carbamic acid benzyl ester


name: [4-Amino-1-(pyrrolidine-1-carbonyl)-butyl]-carbamic acid benzyl ester


name: 2-{4-[2-(7,9-Dioxo-8-aza-spiro[4.5]dec-8-yl)-ethyl]-piperazin-1-yl}-benzoic acid ethyl ester


name: 5-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-pentanoic acid (4-isopropyl-phenyl)-amide hydrochloride


name: 5-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-pentanoic acid (4-sec-butyl-phenyl)-amide hydrochloride


name: 5-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-pentanoic acid (3-tert-butyl-phenyl)-amide hydrochloride


name: 5-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-pentanoic acid (3-isopropyl-phenyl)-amide hydrochloride


name: 5-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-pentanoic acid (4-tert-butyl-phenyl)-amide hydrochloride


name: 3-{5-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-pentanoylamino}-benzoic acid tert-butyl ester hydrochloride


name: 5-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-pentanoic acid (2-hydroxy-phenyl)-amide hydrochloride


name: 6-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-hexanoic acid (3-isopropyl-phenyl)-amide hydrochloride


name: 6-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-hexanoic acid (4-tert-butyl-phenyl)-amide hydrochloride


name: 5-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-pentanoic acid 2-hydroxy-benzylamide hydrochloride


name: 6-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-hexanoic acid (4-isopropyl-phenyl)-amide hydrochloride


name: 6-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-hexanoic acid (3-tert-butyl-phenyl)-amide hydrochloride


name: 6-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-hexanoic acid 2-methoxy-benzylamide hydrochloride


OXYMETAZOLINE HYDROCHLORIDE

A hydrochloride salt resulting from the reaction of equimolar quantities of oxymetazoline and hydrogen chloride. A direct-acting sympathomimetic with marked alpha-adrenergic activity, it is a vasoconstrictor that is used to relieve nasal congestion.


name: 6-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-hexanoic acid (4-sec-butyl-phenyl)-amide hydrochloride


name: 6-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-hexanoic acid 2-hydroxy-benzylamide hydrochloride


name: 2-Allylamino-8-methoxy-1,2,3,4-tetrahydro-naphthalene-1-carboxylic acid methyl ester


name: 5-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-pentanoic acid (2-aminooxy-phenyl)-amide hydrochloride


name: 5-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-pentanoic acid 2-methoxy-benzylamide hydrochloride


name: 6-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-hexanoic acid (5-tert-butyl-2-hydroxy-phenyl)-amide hydrochloride


name: 6-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-hexanoic acid (2-hydroxy-phenyl)-amide hydrochloride


phosphoramidon

A dipeptide isolated from the cultures of Streptomyces tanashiensis.


name: Bromo-acetic acid 7-methoxy-1-(2-propionylamino-ethyl)-naphthalen-2-yl ester


name: Chloro-acetic acid 7-methoxy-1-(2-propionylamino-ethyl)-naphthalen-2-yl ester


name: 3-[4-(2-Acetylaminoethyl)-6-methoxynaphth-2-yl]benzoic acid methyl ester


name: {4-[(3-Methoxy-phenyl)-methyl-amino]-phenyl}-carbamic acid ethyl ester


A member of the class of  tryptamines  that is melatonin with a hydroxy group substituent at position 6.


clorgiline

An aromatic ether that is the 2,4-dichlorophenyl ether of 3-aminopropan-1-ol in which the nitrogen is substituted by a methyl group and a prop-1-yn-3-yl group. A monoamine oxidase inhibitor, it was formerly used as an antidepressant.


harmaline

A harmala alkaloid in which the harman skeleton is methoxy-substituted at C-7 and has been reduced across the 3,4 bond.


mesuaxanthone A

A member of the class of xanthones that is 9H-xanthen-9-one substituted by hydroxy groups at bpositions 1 and 5 and a methoxy group at position 3.


RHAMNOCITRIN

A monomethoxyflavone that is the 7-methyl ether derivative of  kaempferol.


The parent of the class of 2-acetamidofluorenes, being an ortho-fused polycyclic arene that consists of 9H-fluorene bearing an acetamido substituent at position 2. It is a carcinogenic and mutagenic derivative of fluorene.


ACACETIN

A monomethoxyflavone that is the 4'-methyl ether derivative of apigenin.


tranylcypromine

A 2-phenylcyclopropan-1-amine that is the (1R,2S)-enantiomer of tranylcypromine.


name: Methyl-carbamic acid 8-chloro-3-[(Z)-ethylimino]-4-methyl-1,2,3,4-tetrahydro-cyclopenta[b]indol-7-yl ester


hispidol

A hydroxyaurone that is aurone substituted by hydroxy groups at positions 6 and 4' respectively.


KAEMPFERIDE

A monomethoxyflavone that is the 4'-O-methyl derivative of kaempferol.


name: Methyl-carbamic acid 8-bromo-3-[(Z)-ethylimino]-4-methyl-1,2,3,4-tetrahydro-cyclopenta[b]indol-7-yl ester


OSTHENOL

A hydroxycoumarin that is umbelliferone in which the hydrogen at position 8 has been replaced by a prenyl group.


PURPURIN

A trihydroxyanthraquinone derived from anthracene by substitution with oxo groups at C-9 and C-10 and with hydroxy groups at C-1, C-2 and C-4.


name: Dimethyl-carbamic acid 8-bromo-4-methyl-3-[(Z)-methylimino]-1,2,3,4-tetrahydro-cyclopenta[b]indol-7-yl ester


name: Methyl-carbamic acid 8-bromo-4-methyl-3-[(Z)-methylimino]-1,2,3,4-tetrahydro-cyclopenta[b]indol-7-yl ester


BELLIDIFOLIN

A member of the xanthone family that is bellidin substituted with a methyl group at O-3.  A natural product found  particularly in Swertia chirata and Gentianella campestris.


name: Butyl-carbamic acid 8-bromo-4-methyl-3-[(Z)-methylimino]-1,2,3,4-tetrahydro-cyclopenta[b]indol-7-yl ester


pentamidine

A diether consisting of pentane-1,5-diol in which both hydroxyl hydrogens have been replaced by 4-amidinophenyl groups. A  trypanocidal drug that is used for treatment of cutaneous leishmaniasis and Chagas disease.


XANTHONE

The parent compound of the xanthone class consisting of xanthene bearing a single oxo substituent at position 9.


trioxsalen

7H-Furo[3,2-g]chromen-7-one in which positions 2, 5, and 9 are substituted by methyl groups. Like other psoralens, trioxsalen causes photosensitization of the skin. It is administered orally in conjunction with UV-A for phototherapy treatment of vitiligo. After photoactivation it creates interstrand cross-links in DNA, inhibiting DNA synthesis and cell division, and can lead to cell injury; recovery from the cell injury may be followed by increased melanisation of the epidermis.


name: 2-Methyl-6-phenyl-4-phenylethynyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid 5-benzyl ester 3-ethyl ester


name: (2-Chloropurin-9-yl)-3,4-dihydroxytetrahydrothiphene-2-carboxylic acid methyl amide


name: rac-2-((2-(Furan-2-yl)-8-methyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)amino)hexanoic acid ethyl ester


A derivative of adenosine in which the 5'-hydroxymethyl group is replaced by N-ethylcarboxamido and one of the hydrogens of the exocyclic amino function is substituted by a 3-iodo-4-aminobenzyl group.


name: 2-Methyl-6-phenyl-4-phenylethynyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid 3-ethyl ester 5-(4-nitro-benzyl) ester


name: 4,6-Diethyl-5-ethylsulfanylcarbonyl-2-phenyl-nicotinic acid 2-fluoro-ethyl ester


name: (2R,3S,4R)-2-[2-chloro-6-(3-iodobenzylamino)purin-9-yl)-3,4-dihydroxytetrahydrothiophene-2-carboxylic acid methyl amide


name: [2-(9-Chloro-2-furan-2-yl-[1,2,4]triazolo[1,5-c]quinazolin-5-ylcarbamoyl)-ethyl]-carbamic acid tert-butyl ester


name: 4,6-Diethyl-5-ethylsulfanylcarbonyl-2-phenyl-nicotinic acid propyl ester


name: 2-Methyl-6-phenyl-4-phenylethynyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid 3-ethyl ester 5-(3-nitro-benzyl) ester


A methyladenosine compound with one methyl group attached to N(6) of the adenine nucleobase.


name: 6-Ethyl-5-ethylsulfanylcarbonyl-2-phenyl-4-propyl-nicotinic acid 3-fluoro-propyl ester


name: 5-Oxo-2-phenyl-4-propyl-7,8-dihydro-5H-thiopyrano[4,3-b]pyridine-3-carboxylic acid ethyl ester


name: 5-[2-Chloro-6-(3-iodo-benzylamino)-purin-9-yl]-3,4-dihydroxy-tetrahydro-furan-2-carboxylic acid methyl ester


name: 9-Methyl-2-phenyl-5,9-dihydro-[1,2,4]triazolo[5,1-a][2,7]naphthyridine-6-carboxylic acid methyl ester


cordysinin B

A member of the class of adenosines that is adenosine in which the hydroxy group at position 2' is replaced by a methoxy group. It has been isolated from the mycelia of Cordyceps sinensis.


name: rac-2-(2-Furan-2-yl-8-methyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-ylamino)propanoic acid ethyl ester


name: (S)-2-((2-(Furan-2-yl)-8-methyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)amino)succinic acid diethyl ester


name: 2-Methyl-6-phenyl-4-phenylethynyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid 3-ethyl ester 5-(4-trifluoromethyl-benzyl) ester


name: (S)-2-Methyl-6-phenyl-4-phenylethynyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid 5-benzyl ester 3-ethyl ester


name: [4-(9-Chloro-2-furan-2-yl-[1,2,4]triazolo[1,5-c]quinazolin-5-ylcarbamoyl)-butyl]-carbamic acid tert-butyl ester


name: 6-Ethyl-5-ethylsulfanylcarbonyl-2-(2-fluoro-phenyl)-4-propyl-nicotinic acid propyl ester


name: 8-Amino-4-oxo-4,5-dihydro-[1,2,4]triazolo[1,5-a]quinoxaline-2-carboxylic acid ethyl ester


name: 6-Ethyl-5-ethylsulfanylcarbonyl-2-(3-fluoro-phenyl)-4-propyl-nicotinic acid propyl ester


name: 6-Ethyl-5-ethylsulfanylcarbonyl-2-(4-fluoro-phenyl)-4-propyl-nicotinic acid propyl ester


name: [3-(9-Chloro-2-furan-2-yl-[1,2,4]triazolo[1,5-c]quinazolin-5-ylcarbamoyl)-propyl]-carbamic acid tert-butyl ester


name: [5-(9-Chloro-2-furan-2-yl-[1,2,4]triazolo[1,5-c]quinazolin-5-ylcarbamoyl)-pentyl]-carbamic acid tert-butyl ester


name: 2-Methyl-6-phenyl-4-phenylethynyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid 5-(3,5-dinitro-benzyl) ester 3-ethyl ester


name: 2-Methyl-6-phenyl-4-phenylethynyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid 5-(3,5-bis-trifluoromethyl-benzyl) ester 3-ethyl ester


A  monocarboxylic acid amide that is the propyl amide of adenosine 5'-carboxylic acid.


name: 5-(9-Chloro-2-furan-2-yl-[1,2,4]triazolo[1,5-c]quinazolin-5-ylcarbamoyl)-pentanoic acid benzyl ester


name: 6-Ethyl-5-(2-hydroxy-ethylsulfanylcarbonyl)-2-phenyl-4-propyl-nicotinic acid propyl ester


name: 2-Methyl-6-phenyl-4-phenylethynyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid 3-ethyl ester 5-(3-methyl-benzyl) ester


name: [6-(9-Chloro-2-furan-2-yl-[1,2,4]triazolo[1,5-c]quinazolin-5-ylcarbamoyl)-hexyl]-carbamic acid tert-butyl ester


name: 6-Ethyl-5-(2-fluoro-ethylsulfanylcarbonyl)-2-phenyl-4-propyl-nicotinic acid propyl ester


name: 2-Methyl-6-phenyl-4-((E)-styryl)-1,4-dihydro-pyridine-3,5-dicarboxylic acid 5-benzyl ester 3-ethyl ester


name: 7-(9-Chloro-2-furan-2-yl-[1,2,4]triazolo[1,5-c]quinazolin-5-ylcarbamoyl)-heptanoic acid methyl ester


name: 2-Methyl-4-[(E)-2-(4-nitro-phenyl)-vinyl]-6-phenyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid diethyl ester


name: 6-Ethyl-5-ethylsulfanylcarbonyl-4-(3-fluoro-propyl)-2-phenyl-nicotinic acid propyl ester


name: 2-Methyl-6-phenyl-4-phenylethynyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid 3-ethyl ester 5-(2-trimethylsilanyl-ethyl) ester


name: 2-Methyl-6-phenyl-4-phenylethynyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid 5-benzyl ester 3-propyl ester


name: 2-Ethyl-6-phenyl-4-phenylethynyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid 5-benzyl ester 3-ethyl ester


name: (2-Amino-ethyl)-carbamic acid 4-(2,6-dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)-phenoxymethyl ester


name: 2-Methyl-4-[(E)-2-(4-nitro-phenyl)-vinyl]-6-phenyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid 5-benzyl ester 3-ethyl ester


name: 2-Methyl-6-phenyl-4-phenylethynyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid diethyl ester


name: 2-Methyl-6-phenyl-4-phenylethynyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid 3-ethyl ester 5-(3-phenyl-propyl) ester


name: (9-Chloro-2-furan-2-yl-[1,2,4]triazolo[1,5-c]quinazolin-5-yl)-carbamic acid tert-butyl ester


name: 6-Ethyl-5-(3-fluoro-propylsulfanylcarbonyl)-2-phenyl-4-propyl-nicotinic acid propyl ester


name: 2-Methyl-6-phenyl-4-phenylethynyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid 3-ethyl ester 5-(3-iodo-benzyl) ester


TRIAPINE

Triapine is a synthetic heterocyclic carboxaldehyde thiosemicarbazone with potential antineoplastic activity. Triapine inhibits the enzyme ribonucleotide reductase, resulting in the inhibition of the conversion of ribonucleoside diphosphates to deoxyribonucleotides necessary for DNA synthesis. This agent has been shown to inhibit tumor growth in vitro.


NINTEDANIB ESYLATE

An organosulfonate salt obtained by combining nintedanib with one molar equivalent of ethanesulfonic acid. A kinase inhibitor used for the treatment of idiopathic pulmonary fibrosis and cancer.


A member of the class of aminopyrimidines that is pyrimidine-2,4-diamine substituted at positions N-2 and N-4 by 3-methoxy-4-(morpholin-4-yl)phenyl and quinolin-3-yl groups respectively.


A member of the class of phenylureas obtained by formal condensation of the carboxy group of (3-{5-[4-(aminomethyl)phenyl]pyrrolo[2,3-b]pyridin-3-yl}phenyl)carbamic acid with the amino group of 2-phenoxyaniline. An inhibitor of tyrosine kinase.


PQIP

A member of the class of imidazopyrazines that is imidazo[1,5-a]pyrazin-8-amine carrying additional 2-phenylquinolin-7-yl and 3-(4-methylpiperazin-1-yl)cyclobutyl groups at positions 1 and 3 respectively. It is an inhibitor of insulin growth factor 1 receptor (IGF-1 receptor, IGFR1R) tyrosine kinase.


name: 9H-Imidazo[1,5-a]pyrrolo[2,1-c][1,4]benzodiazepine-1-carboxylic acid, 11,12,13,13a-tetrahydro-7-methoxy-9-oxo-, ethyl ester, (13aS)-


brequinar

A quinolinemonocarboxylic acid that is quinoline substituted by 2'-fluoro[1,1'-biphenyl]-4-yl, methyl, carboxy and fluoro groups at positions 2, 3, 4, and 6, respectively. It is an inhibitor of dihydroorotate dehydrogenase, an enzyme that is required for de novo pyrimidine biosynthesis. The compound exhibits antineoplastic and antiviral properties.


name: X1-(4-Chloro-phenyl)-1H-pyrazole-3,5-dicarboxylic acid 3-benzylamide 5-phenylamide


name: 1-(4-Chloro-phenyl)-1H-pyrazole-3,5-dicarboxylic acid 5-phenylamide 3-[(pyridin-3-ylmethyl)-amide]


BREQUINAR SODIUM

An organic sodium salt of brequinar.


name: 2-(1,1'-Biphenyl-4-yl)-5-chloro-3-methyl-4-quinolinecarboxylic acid sodium salt


A member of the class of 1,3-thiazoles that is 1,3-thiazole substituted by (2E)-2-(2-carboxybenzylidene)hydrazinyl and 2-chlorophenyl groups at positions 2 and 4, respectively. It is a potent inhibitor of human dihydroorotate dehydrogenase (hDHODH) with IC50 of 32 nM. It exhibits antineoplastic activity and broad-spectrum antiviral activity against various RNA viruses including influenza A, Zika, Ebola, and SARS-CoV-2 viruses.


LAPACHOL

A hydroxy-1,4-naphthoquinone that is 1,4-naphthoquinone substituted by hydroxy and 3-methylbut-2-en-1-yl groups at positions 2 and 3, respectively. It is a natural compound that exhibits antibacterial and anticancer properties, first isolated in 1882 from the bark of Tabebuia avellanedae.


name: 2-Biphenyl-4-yl-6-fluoro-3-methyl-quinoline-4-carboxylic acid methyl ester


ascofuranol

A dihydroxybenzaldehyde that is 2,4-dihydroxybenzaldehyde which is substituted by a {(2E,6E)-7-[(2S,4S)-4-hydroxy-5,5-dimethyltetrahydrofuran-2-yl]-3-methylocta-2,6-dien-1-yl} group at position 3, chlorine at position 5, and a methyl group at position 6. A meroterpenoid produced by various filamentous fungi, including Acremonium egyptiacum.


IOTYROSINE

The monoiodotyrosine that is L-tyrosine carrying an iodo-substituent at position C-3 of the benzyl group.


cisapride

The amide resulting from formal condensation of 4-amino-5-chloro-2-methoxybenzoic acid with cis-1-[3-(4-fluorophenoxy)propyl]-3-methoxypiperidin-4-amine. It has been used (as its monohydrate or as its tartrate) for the treatment of gastro-oesophageal reflux disease and for non-ulcer dyspepsia, but its propensity to cause cardiac arrhythmias resulted in its complete withdrawal from many countries, including the U.K., and restrictions on its use elsewhere.


name: 4-(5-Chloro-3-{1-[2-(2-oxo-imidazolidin-1-yl)-ethyl]-piperidin-4-yl}-indol-1-yl)-benzoic acid methyl ester


name: Carbamic acid, (3-chloro-5-(1-((6-(2-(5-ethyl-4-methyl-2-thiazolyl)ethyl)-4-(4-morpholinyl)-2-pyridinyl)amino)ethyl)phenyl)-, 1-methylethyl ester


name: 3-[2-(Dim ethylamino)ethoxy]-2-phenyl-4-quinolinecarboxylic acid, 2-(methoxycarbonyl)-2-phenylhydrazide


name: [4-(5-Chloro-3-{1-[2-(2-oxo-imidazolidin-1-yl)-ethyl]-piperidin-4-yl}-indol-1-yl)-phenyl]-acetic acid methyl ester


amsacrine

A sulfonamide that is N-phenylmethanesulfonamide substituted by a methoxy group at position 3 and an acridin-9-ylamino group at position 4. It exhibits  antineoplastic activity.


name: N''-[3-(4-methyl-piperazin-1-ylmethyl)-2-phenyl-quinoline-4-carbonyl]-N-phenyl-hydrazinecarboxylic acid methyl ester


bedaquiline

A quinoline-based antimycobacterial drug used (as its fumarate salt) for the treatment of pulmonary multi-drug resistant tuberculosis by inhibition of ATP synthase, an enzyme essential for the replication of the mycobacteria.


lumefantrine

A member of the class of fluorenes that is 9-(p-chlorobenzylidene)-9H-fluorene which is substitutec by chlorine at positions 2 and 7, and by a 2-(dibutylamino)-1-hydroxyethyl group at position 4. An antimalarial drug used in combination with artemether for the treatment of multi-drug resistant strains of falciparum malaria.


rilpivirine

An aminopyrimidine that is pyrimidine-2,4-diamine in which the amino groups at positions 2 and 4 are substituted by 4-cyanophenyl and 4-[(E)-2-cyanovinyl]-2,6-dimethylphenyl groups respectively. Used for treatment of HIV.


name: N-phenyl-N''-(2-phenyl-3-piperidin-4-ylmethyl-quinoline-4-carbonyl)-hydrazinecarboxylic acid methyl ester


name: N''-[3-(4-benzyl-piperazin-1-ylmethyl)-2-phenyl-quinoline-4-carbonyl]-N-phenyl-hydrazinecarboxylic acid methyl ester


name: 4-{3-(5-chloro-pyridin-2-ylcarbamoyl)-4-[4-(N,N-dimethyl-carbamimidoyl)-benzoylamino]-phenoxy}-benzoic acid methyl ester


name: N''-[3-(4-isopropyl-piperazin-1-ylmethyl)-2-phenyl-quinoline-4-carbonyl]-N-phenyl-hydrazinecarboxylic acid methyl ester


name: {3-(5-chloro-pyridin-2-ylcarbamoyl)-4-[4-(N,N-dimethyl-carbamimidoyl)-benzoylamino]-phenoxy}-acetic acid ethyl ester


name: 4-(4-{3-[2-(3-Trifluoromethyl-benzoylamino)-acetylamino]-azetidin-1-yl}-cyclohexyl)-benzoic acid methyl ester


name: cis-4-{3-[2-(1-Benzyl-5-trifluoromethyl-1H-indazol-3-ylamino)-acetylamino]-azetidin-1-yl}-cyclohexane carboxylic acid ethyl ester


name: N''-[3-(4-cyclohexyl-piperazin-1-ylmethyl)-2-phenyl-quinoline-4-carbonyl]-N-phenyl-hydrazinecarboxylic acid methyl ester


name: cis-4-(3-{2-[1-(2,2,2-Trifluoro-ethyl)-5-trifluoromethyl-1H-indazol-3-ylamino]-acetylamino}-azetidin-1-yl)-cyclohexane carboxylic acid ethyl ester


tedisamil

A member of the class of diazabicyclononanes that is (1s,5s)-3,7-diazaspiro[bicyclo[3.3.1]nonane-9,1'-cyclopentane] in which the hydrogens at positions 3 and 7 are replaced by cyclopropylmethyl groups. It is a potassium channel blocker and an antiarrhythmic agent currently currently in development for the treatment of atrial fibrillation.


A propanoate ester that is propyl propanoate substituted by a benzyl and phenyl group at position 1, a methyl group at position 2 and a dimethylamino group at position 3.


name: N''-[3-(1-tert-butyl-piperidin-4-yloxy)-2-phenyl-quinoline-4-carbonyl]-N-phenyl-hydrazinecarboxylic acid methyl ester


ouabain

A steroid hormone that is a multi-hydroxylated alpha-L-rhamnosyl cardenoloide. It binds to and inhibits the plasma membrane Na(+)/K(+)-ATPase (sodium pump). It has been isolated naturally from Strophanthus gratus.


name: 2,3-Dihydro-1H-indole-3-carboxylic acid (3S,7S)-10-oxo-8-aza-tricyclo[5.3.1.0*3,8*]undec-5-yl ester


name: [2-(4-Diethylamino-phenylcarbamoyl)-8-methoxy-1,2,3,4-tetrahydro-naphthalen-2-yl]-methyl-carbamic acid isobutyl ester


papaverine

A benzylisoquinoline alkaloid that is isoquinoline substituted by methoxy groups at positions 6 and 7 and a 3,4-dimethoxybenzyl group at position 1. It has been isolated from Papaver somniferum.


name: cis-4-{3-[2-(1-Methyl-5-trifluoromethyl-1H-indazol-3-ylamino)-acetylamino]-azetidin-1-yl}-cyclohexane carboxylic acid ethyl ester


A triazolopyridine that is 3H-[1,2,3]triazolo[4,5-b]pyridine substituted by a 4-{(3-chloropyridin-2-yl)[(3R)-piperidin-3-yl]carbamoyl}phenyl group at position 3. It is a potent inhibitor of PCSK9.


name: cis-4-{3-[2-(5-Trifluoromethyl-1H-indazol-3-ylamino)-acetylamino]-azetidin-1-yl}-cyclohexane carboxylic acid ethyl ester


GLABRIDIN

A member of the class of  hydroxyisoflavans that is (R)-isoflavan substituted by hydroxy groups at positions 2' and 4' and a 2,2-dimethyl-2H-pyran group across positions 7 and 8 respectively.


GLYASPERIN D

A member of the class of  hydroxyisoflavans that is  (R)-isoflavan substituted by hydroxy groups at positions 2' and 4', methoxy groups at positions 5 and 7 and a prenyl group at position 6. It has been isolated from Glycyrrhiza uralensis.


GLYASPERIN C

A methoxyisoflavan that is (R)-isoflavan substituted by a methoxy group at position 5, hydroxy groups at positions 7, 2' and 4' and a prenyl group at position 6. It has been isolated from Glycyrrhiza uralensis.


A member of the class of phenylureas that is urea in which one of the nitrogens has been substituted by a 5-tert-butyl-1,2-oxazol-3-yl group, while the other has been substituted by a 3-fluoro-4-hydroxyphenyl group, the hydroxy group has been converted to the corresponding 1H-pyrazolo[3,4-d]pyrimidin-4-yl ether. It is an FLT3 (fms-like tyrosine kinase 3)and Wnt/beta-catenin signaling inhibitor.


A member of the class of indazoles that is linifanib in which the 2-fluoro-5-methylphenyl group has been replaced by a 2-methylphenyl group. A cell-permeable 3-aminoindazolylurea compound, it acts as a potent and ATP-competitive inhibitor of VEGFR2/KDR (IC50 = 3 nM) as well as Flt3 and cKit (IC50 = 4 to 20 nM). Shown to block VEGF-induced VEGFR2 phosphorylation in 3T3-murine fibroblasts in vitro.


A member of the class of pyrimidines that is 5-methylpyrimidine-2,4-diamine in which the amino group at position 2 is substituted by a p-(4-methylpiperazin-1-yl)phenyl group, while that at position 4 is substituted by a m-(tert-butylsulfamoyl)phenyl group. A Janus kinase 2 (JAK2) inhibitor.


name: Sulfamic Acid 4-{3-[(4-cyano-phenyl)-[1,2,4]triazol-4-yl-amino]-propylsulfanyl}-phenyl Ester


A dihydroxyflavone in which the two hydroxy substituents are located at positions 4' and 7.


An androstanoid that is androsta-1,4,6-triene substituted by oxo groups at positions 3 and 17.


name: Sulfamic acid, 2-bromo-4-[(4-cyanophenyl)-1H-1,2,4-triazol-1-ylmethyl]phenyl ester


ALPHA-NAPHTHOFLAVONE

An extended flavonoid resulting from the formal fusion of a benzene ring with the h side of flavone. A synthetic compound, it is an inhibitor of aromatase (EC 1.14.14.14).


formestane

A 17-oxo steroid that is androst-4-ene-3,17-dione in which the hydrogen at position 4 is replaced by a hydroxy group. Formestane was the first selective, type I steroidal aromatase inhibitor, suppressing oestrogen production from anabolic steroids or prohormones. It was formerly used in the treatment of oestrogen-receptor positive breast cancer in post-meopausal women. As it has poor oral bioavailability, it had to be administered by (fortnightly) intramuscular injection. It fell out of use with the subsequent development of cheaper, orally active aromatase inhibitors. Formestane is listed by the World Anti-Doping Agency as a substance prohibited from use by athletes.


A hydroxyflavonoid in which the flavone nucleus is substituted at position 7 by a hydroxy group.


ANDROSTENEDONE

A steroid that consists of androstane having double bonds at positions 1 and 4 and two keto groups at positions 3 and 17.


An  androstanoid that is (5alpha)-androst-3-ene substituted by an oxo group at position 5.


name: Pyridin-4-yl-acetic acid adamantan-1-yl ester


name: (1R,2R,3R,5S)-(-)-Pyridin-4-yl-acetic acid 2,6,6-trimethyl-bicyclo[3.1.1]hept-3-yl ester


name: (+)-Pyridin-4-yl-acetic acid 1,7,7-trimethyl-bicyclo[2.2.1]hept-2-yl ester


name: Pyridin-4-yl-acetic acid 4-ethyl-cyclohexyl ester


name: Pyridin-4-yl-acetic acid (S)-2,6,6-trimethyl-bicyclo[3.1.1]hept-3-yl ester


name: Pyridin-4-yl-acetic acid (cis)-4-methyl-cyclohexyl ester


name: (+)-Pyridin-4-yl-acetic acid 2-isopropyl-5-methyl-cyclohexyl ester


boldenone undecylenate

An  3-oxo-Delta(1),Delta(4)-steroid substituted by an oxo group at position 3 and a beta-hydroxy group at position 17. It is an  anabolic androgenic steroid that has been developed for veterinary use.


name: Pyridin-4-yl-acetic acid cyclohexyl ester


name: (endo)-Pyridin-4-yl-acetic acid bicyclo[2.2.1]hept-2-en-2-yl ester


LIQUIRTIGENIN

A dihydroxyflavanone compound having the two hydroxy substituents at the 4'- and 7-positions. Isolated from the root of Glycyrrhizae uralensis, it is a selective agonist for oestrogen receptor beta.


name: Pyridin-4-yl-acetic acid (3R,6R)-3,6,8,8-tetramethyl-octahydro-3a,7-methano-azulen-6-yl ester


A 6beta-hydroxy steroid that is androst-4-ene-3,17-dione substituted by a beta-hydroxy group at position 6.


PINOCEMBRIN

A dihydroxyflavanone in which the two hydroxy groups are located at positions 5 and 7. A natural product found in Piper sarmentosum and Cryptocarya chartacea.


MEXILETINE HYDROCHLORIDE

A hydrochloride composed of equimolar amounts of mexiletine and hydrogen chloride.


piclamilast

A monocarboxylic acid amide resulting from the formal condensation of the carboxy group of 3-(cyclopentyloxy)-4-methoxybenzoic acid with the primary amino group of 3,5-dichloropyridin-4-amine.


name: 4-{2-[6-Amino-3-(3-cyclopentyloxy-4-methoxy-benzyl)-3H-purin-8-yl]-2-methyl-propoxy}-benzoic acid methyl ester


(-)-ROLIPRAM

The (R)-enantiomer of rolipram.


name: Trifluoro-methanesulfonic acid 8-(3-cyano-phenyl)-[1,7]naphthyridin-6-yl ester


A member of the class of tryptamines that is tryptamine substituted by a methyl group at position 5.


name: Trifluoro-methanesulfonic acid 7-propylamino-5,6,7,8-tetrahydro-naphthalen-1-yl ester


name: {4-Hydroxy-1-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-ylmethyl}-carbamic acid tert-butyl ester


A 2-arylethylamine compound where the aryl moiety is 4-bromo-2,5-dimethoxyphenyl.


N,O-dimethylserotonin

A tryptamine derivative hahing a methoxy group at position 5 of the indole portion and a methyl substituent on the side-chain nitrogen.


name: acetic acid (R)-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-yl ester


A member of the class of tryptamines that is tryptamine in which the the indole ring has been substituted by a hydroxy group at position 4.


name: Phosphoric acid mono-[1-butyl-3-(2-dimethylamino-ethyl)-1H-indol-4-yl] ester


name: 5-(4-Chloro-phenyl)-2-pyridin-4-yl-1H-pyrrole-3-carboxylic acid benzyl ester


A 4-aryl-5-(2-hydroxyalkyl)pyridine derivative used as a glucagon receptor antagonist.


name: 5-(4-Chloro-phenyl)-2-pyridin-4-yl-1H-pyrrole-3-carboxylic acid ethyl ester


ALISKIREN FUMARATE

The hemifumarate salt of aliskiren.


name: (3-Phenyl-propyl)-phosphonic acid (S)-1-((1S,2S,4R)-4-butylcarbamoyl-1-cyclohexylmethyl-2-hydroxy-pentylcarbamoyl)-pentyl ester ethyl ester


name: (3-Phenyl-propyl)-phosphonic acid (R)-1-((1S,2R,3S)-1-cyclohexylmethyl-2,3-dihydroxy-5-methyl-hexylcarbamoyl)-butyl ester ethyl ester


name: (3-Phenyl-propyl)-phosphonic acid (R)-1-((1S,2R,3S)-1-cyclohexylmethyl-3-cyclopropyl-2,3-dihydroxy-propylcarbamoyl)-butyl ester ethyl ester


name: (3-Phenyl-propyl)-phosphonic acid (R)-1-((1S,2S,4R)-4-butylcarbamoyl-1-cyclohexylmethyl-2-hydroxy-pentylcarbamoyl)-pentyl ester ethyl ester


name: Benzoic acid 2-{4-[(3R,4R)-3-(naphthalen-2-ylmethoxy)-piperidin-4-yl]-phenoxy}-ethyl ester


name: [3-((2S,4S,5S,7R)-4-Amino-7-butylcarbamoyl-5-hydroxy-2-isopropyl-octyl)-phenoxy]-acetic acid methyl ester


name: Benzoic acid 4-[(3R,4R)-3-(naphthalen-2-ylmethoxy)-piperidin-4-yl]-benzyl ester


name: {4-[2-(2,6-Dimethyl-phenoxy)-1-phenyl-1H-pyrrolo[3,2-b]pyridine-3-carbonyl]-piperazin-2-yl}-acetic acid methyl ester


name: 3-Methoxy-benzoic acid 4-[(3R,4R)-3-(naphthalen-2-ylmethoxy)-piperidin-4-yl]-benzyl ester


name: 2-[1-(1-Cyclohexylmethyl-2,3-dihydroxy-5-methyl-hexylcarbamoyl)-ethylamino]-4-phenyl-butyric acid ethyl ester


name: 2-[1-(1-Cyclohexylmethyl-2,3-dihydroxy-5-methyl-hexylcarbamoyl)-3-methyl-butylamino]-4-phenyl-butyric acid ethyl ester


name: [2-((2S,4S,5S)-4-Amino-7-butylcarbamoyl-5-hydroxy-2-isopropyl-octyl)-5-tert-butyl-phenoxy]-acetic acid ethyl ester


name: {1-[1-(1-Cyclohexylmethyl-2,3-dihydroxy-propylcarbamoyl)-ethylcarbamoyl]-2-phenyl-ethyl}-carbamic acid tert-butyl ester


name: Nicotinic acid 2-{4-[(3R,4R)-3-(naphthalen-2-ylmethoxy)-piperidin-4-yl]-phenoxy}-ethyl ester


name: 17-trifluoromethylphenyl-13,14-dihydro trinor Prostaglandin F1alpha


name: (2S, 3aS, 4R, 9bR)-4-(4-Hydroxy-phenyl)-2-trifluoromethyl-1,2,3,3a,4,9b-hexahydro-cyclopenta[c]chromen-8-ol


coumestrol

A member of the class of coumestans that is coumestan with hydroxy substituents at positions 3 and 9.


An estradiol that is estra-1,3,5(10)-triene substituted by hydroxy groups at positions 3 and 17 (the 17alpha stereoisomer).


name: 2,3-Bis-(4-hydroxy-phenyl)-propionic acid methyl ester


androstenediol

A 3beta-hydroxy-Delta(5)-steroid that is 3beta-hydroxyandrost-5-ene carrying an additional hydroxy group at position 17beta.


bisphenol AF

An organofluorine compound that is  bisphenol A with its methyl hydrogens replaced by fluorines.


A chromanol that is chroman-6-ol which is substituted at positions 2, 3, and 4 by p-(2-pyrrolidin-1-ylethoxy)phenyl, p-hydroxyphenyl, and methyl groups, respectively (the 2R,3R,4S diastereoisomer).


RALOXIFENE HYDROCHLORIDE

A hydrochloride salt resulting from the reaction of equimolar amounts of raloxifene and hydrogen chloride.


DEMECLOCYCLINE HYDROCHLORIDE

The hydrochloride salt of demeclocycline. A tetracycline antibiotic, it is used (mainly as the hydrochloride) for the treatment of Lyme disease, acne and bronchitis, as well as for hyponatraemia (low blood sodium concentration) due to the syndrome of inappropriate antidiuretic hormone (SIADH) where fluid restriction alone has been ineffective.


hexachlorophene

An organochlorine compound that is diphenylmethane in which each of the phenyl groups is substituted by chlorines at positions 2, 3, and 5, and by a hydroxy group at position 6. An antiseptic that is effective against Gram-positive organisms, it is used in soaps and creams for the treatment of various skin disorders. It is also used in agriculture as an acaricide and fungicide, but is not approved for such use within the European Union.


A member of the class of aminoquinolines that is is quinoline substituted by 5-methylfuran-2-yl, (1-methylpiperidin-4-yl)amino, methoxy, and 3-(pyrrolidin-1-yl)propoxy groups at positions 2, 4, 6 and 7, respectively. It is a dual G9a/DNA methyltransferases inhibitor with antitumor activity. It inhibits G9a, DNMT1, DNMT3A, DNMT3B and GLP (IC50 = 8 nM, 382 nM, 85 nM, 1200 nM and 2 nM, respectively).


METRIBOLONE

A synthetic non-aromatisable androgen and anabolic steroid. It binds strongly to the androgen receptor and has therefore also been used as an affinity label for this receptor in the prostate and in prostatic tumors.


A 11beta-hydroxy steroid that is  progesterone substituted by a beta-hydroxy group at position 11.


name: Acetic acid, (((5R)-5-((2R)-2-(4,5-diphenyl-2-oxazolyl)-1-pyrrolidinyl)-5,6,7,8-tetrahydro-1-naphthalenyl)oxy)-, sodium salt


name: Acetic acid, (3-(((1S)-2-(4,5-diphenyl-2-oxazolyl)-2-cyclohexen-1-yl)methyl)phenoxy)-, sodium salt


name: 2-(P-Cyanophenyl methylidene hydrazino) adenosine


name: [2-(3,5-Dimethylpyrazol-1-yl)-6-((R)-2-methoxymethylpyrrolidin-1-yl)pyrimidin-4-yl]carbamic Acid Methyl Ester


(R,S)-MEFLOQUINE

An optically active form of [2,8-bis(trifluoromethyl)quinolin-4-yl]-(2-piperidyl)methanol having (+)-(11R,2'S)-erythro-configuration. An antimalarial agent, used in racemic form, which acts as a blood schizonticide; its mechanism of action is unknown.


name: {2-[6-(4-Nitro-benzylsulfanyl)-purin-9-ylmethyl]-phenyl}-carbamic acid tert-butyl ester


name: {3-[3-(4-Cyano-3-methoxy-phenyl)-ureido]-benzyl}-carbamic acid (R)-2-cyano-1-ethyl-ethyl ester


name: Acetic acid (methyl-{2-[2-(3-oxazol-5-yl-1H-indol-6-ylamino)-oxazol-5-yl]-phenyl}-carbamoyl)-methyl ester


name: Dimethyl-carbamic acid 6-(7-methoxy-6-oxazol-5-yl-4-oxo-1,4-dihydro-quinolin-2-yl)-indan-1-yl ester


name: 2-[(3-Methoxy-4-oxazol-5-yl-phenylaminooxalyl)-amino]-2-methyl-propionic acid methyl ester


name: {3-[2-(3-Cyano-1-methyl-1H-indol-6-ylamino)-oxazol-5-yl]-benzyl}-carbamic acid 2-dimethylamino-ethyl ester


name: {3-[2-(3-Cyano-1-methyl-1H-indol-6-ylamino)-oxazol-5-yl]-benzyl}-carbamic acid 2-cyano-ethyl ester


name: Acetic acid ({2-[2-(3-cyano-1-methyl-1H-indol-6-ylamino)-oxazol-5-yl]-phenyl}-methyl-carbamoyl)-methyl ester


name: {3-[2-(3-Cyano-1-methyl-1H-indol-6-ylamino)-oxazol-5-yl]-benzyl}-carbamic acid tetrahydro-furan-3-yl ester


name: {2-[2-(3-Cyano-1-methyl-1H-indol-6-ylamino)-oxazol-5-yl]-benzyl}-carbamic acid 2-cyano-ethyl ester


name: {2-[2-(3-Cyano-1-methyl-1H-indol-6-ylamino)-oxazol-5-yl]-benzyl}-carbamic acid tetrahydro-furan-3-yl ester


name: Benzoic acid, 4-(1-methyl-2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)ethenyl)-, (E)-


name: Benzoic acid, 4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)ethenyl)-, (E)-


name: Benzoic acid, 4-(2-(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)ethenyl)-, (E)-


name: Benzoic acid, 4-(4-(2,6,6-trimethyl-1-cyclohexen-1-yl)-3-buten-1-ynyl)-, (E)-


BMS961 is a selective retinoic acid receptor gamma (RARgamma) agonist


name: 4-[(E)-2-(4,4-Dimethyl-thiochroman-6-yl)-propenyl]-benzoic acid methyl ester


name: (Z)-3-[(4-Dimethylaminomethyl-phenylamino)-phenyl-methylene]-2-oxo-2,3-dihydro-1H-indole-6-carboxylic Acid Methyl Ester


name: 1-Isopropyl-4,4-dimethyl-1,2,3,4-tetrahydro-quinoline-6-carboxylic acid 4-ethoxycarbonyl-phenyl ester


name: 1,4,4,7-Tetramethyl-1,2,3,4-tetrahydro-quinoline-6-carboxylic acid 4-ethoxycarbonyl-phenyl ester


name: 4-Phenylamino 3-quinolinecarbonitrile deriv. 27


name: 4-Phenylamino 3-quinolinecarbonitrile deriv. 26


name: {3-[4-Amino-5-(3-hydroxy-phenyl)-pyrrolo[2,3-d]pyrimidin-7-yl]-pyrrolidin-1-yl}-acetic acid methyl ester


name: 3-[4-Amino-5-(3-hydroxy-phenyl)-pyrrolo[2,3-d]pyrimidin-7-yl]-pyrrolidine-1-carboxylic acid tert-butyl ester


name: {(R)-4-[(S)-4-Amino-5-(4-hydroxy-phenyl)-pyrrolo[2,3-d]pyrimidin-7-yl]-pyrrolidin-2-yl}-acetic acid ethyl ester


name: 3-[4-Amino-5-(4-hydroxy-phenyl)-pyrrolo[2,3-d]pyrimidin-7-yl]-pyrrolidine-1-carboxylic acid tert-butyl ester


Src Inhibitor-5

A member of the class of quinazolines that is quinazoline which is substituted at position 4 by a 2-chloro-5-methoxyanilino group, at position 6 by a methoxy group and at position 7 by a 3-(morpholin-4-yl)propoxy group.


name: [(R)-4-((S)-4-Amino-5-phenyl-pyrrolo[2,3-d]pyrimidin-7-yl)-pyrrolidin-2-yl]-acetic acid ethyl ester


name: (2S,3S)-3-(3,4-Dichloro-phenyl)-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester


name: 2-Piperidineacetic acid, alpha-(3,4-dichlorophenyl)-, methyl ester, (alphaR,2R)-


A tertiary amino compound that consists of cyclohexane having piperidin-1-yl and benzothiophen-2-yl groups attached at position 1. A potent dopamine re-uptake inhibitor with a behavioral profile different from that of phencyclidine (PCP) and similar to that of cocaine.


vanoxerine dihydrochloride

A hydrochloride salt that is obtained by reaction of vanoxerine with two equivalents of hydrogen chloride. Potent, competitive inhibitor of dopamine uptake (Ki = 1 nM for inhibition of striatal dopamine uptake). Has > 100-fold lower affinity for the noradrenalin and 5-HT uptake carriers. Also a potent sigma ligand (IC50 = 48 nM). Centrally active following systemic administration.


name: 3-(3,4-Dichloro-phenyl)-8-thia-bicyclo[3.2.1]oct-2-ene-2-carboxylic acid methyl ester


name: 3-(4-Bromo-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid 3-fluoro-propyl ester


name: 3-(4-Bromo-phenyl)-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid 3-fluoro-propyl ester


name: 3-(4-Bromo-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid 2-fluoro-ethyl ester


name: 3-(4-Bromo-phenyl)-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid 2-fluoro-ethyl ester


name: 3-(4-Iodo-phenyl)-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid 2-fluoro-ethyl ester


name: 3-(4-Iodo-phenyl)-8-thia-bicyclo[3.2.1]oct-2-ene-2-carboxylic acid methyl ester


name: 3-(3,4-Dichloro-phenyl)-bicyclo[3.2.1]oct-2-ene-2-carboxylic acid methyl ester


name: 3-Naphthalen-2-yl-8-thia-bicyclo[3.2.1]oct-2-ene-2-carboxylic acid methyl ester


name: 3-(4-Bromo-phenyl)-8-thia-bicyclo[3.2.1]oct-2-ene-2-carboxylic acid methyl ester


name: 3-Naphthalen-2-yl-bicyclo[3.2.1]oct-2-ene-2-carboxylic acid methyl ester


name: 3-(3,4-Dichloro-phenyl)-8-oxa-bicyclo[3.2.1]oct-2-ene-2-carboxylic acid methyl ester