pentamethonium bromide

A quarternary ammonium cation that is cadaverine in which the terminal amino hydrogens are substituted methyl groups. Its bromide and iodide salt exhibits ganglionic blocking activity and used in the treatment of hypertension.


lysophosphatidylcholine (22:4/0:0)

A lysophosphatidylcholine 22:4 in which the docosatetraenoyl group is located at position 1.


A 1-octadecanoyl-2-octadecenoyl-sn-glycero-3-phosphocholine in which the acyl groups specified at positions 1 and 2 are (11Z)-octadecenoyl and octadecanoyl respectively.


An N-acyl-15-methylhexadecasphing-4-enine-1-phosphocholine in which the acyl group has 25 carbons and 2 double bonds.


Major microspecies at pH 7.3.


lysophosphatidylcholine 19:2

A lysophosphatidylcholine in which the remaining acyl group (position unspecified) contains 19 carbons and 2 double bonds.


L-prolinium

An optically active form of prolinium having L-configuration.


phosphatidylcholine (20:2/20:4)

A phosphatidylcholine 40:6 in which the fatty acyl groups at positions 1 and 2 are specified as C20:2 and C20:4 respectively.


A quaternary ammonium ion resulting from the addition of a methyl group to the tertiary amino group of 3-[dodecyl(methyl)amino]propane-1-sulfonic acid.


An alpha-amino-acid cation obtained by protonation of any dimethylarginine.


A sphingomyelin  d18:1 in which the ceramide N-acyl group contains 14 carbons, 1 hydroxy group and 1 double bond.


lysophosphatidylcholine 14:1

A lysophosphatidylcholine in which the remaining acyl group contains 14 carbons and 1 double bond. If R1 is the acyl group and R2 is a hydrogen then the molecule is a 1-acyl-sn-glycero-3-phosphocholine. If R1 is a hydrogen and R2 is the acyl group then the molecule is a 2-acyl-sn-glycero-3-phosphocholine.


decanoylcholine

An acylcholine obtained by formal condensation of the carboxy group of decanoic acid with the hydroxy group of choline.


An organic cation obtained by protonation of the secondary amino group of (R)-tetrindole.


A phosphatidylcholine 34:1 in which one acyl group has 16 carbons and is fully saturated while the other has 18 carbons and 1 double bond (position not specified).


A sphingomyelin in which the sphingoid component is specified as hexadecaphytosphingosine.


An organic cation obtained by protonation of the tertiary amino function of 6-hydroxy-N-methylmyosmine; major species at pH 7.3.


tropiniumone

Conjugate acid of tropinone; major species at pH 7.3.


phosphatidylcholine O-30:2

An alkyl,acyl-sn-glycero-3-phosphocholine in which the alkyl or acyl groups at positions 1 and 2 contain a total of 30 carbons and 2 double bonds.


A cationic sphingoid that is the conjugate acid of 4-hydroxy-15-methylhexadecasphinganine, obtained by protonation of the amino group; major species at pH 7.3.


ethyl green(1+)

An iminium ion that forms the cationic portion of the histological dye 'ethyl green'.


A cationic sphingoid resulting from the protonation of the amino group of L-erythro-sphingosine; major species at pH 7.3.


phosphatidylcholine 37:4

A 1,2-diacyl-sn-glycero-3-phosphocholine in which the acyl groups at C-1 and C-2 contain 37 carbons in total with 4 double bonds.


phosphatidylcholine (18:0/22:6)

A phosphatidylcholine 40:6 in which the fatty acyl groups at positions 1 and 2 are specified as C18:0 and C22:6 respectively.


An ammonium ion resulting from the protonation of the primary amino group of midodrine.


An ammonium ion that is the conjugate acid of 4-aminobutanal; major species at pH 7.3.


An ammonium ion resulting from the protonation of the tertiary amino group of ketotifen.


A sphingomyelin 39:1 obtained by formal condensation of the carboxy group of docosanoic acid with the amino group of 14-methylhexadecasphingosine-1-phosphocholine. It is a metabolite of the nematode Caenorhabditis elegans.


caproylcholine

An acylcholine with an acyl group that is hexanoyl.


1-palmitoyl-2-acyl-sn-glycero-3-phosphocholine in which the 2-acyl group is specified as heptanoyl.


A cationic sphingoid obtained by the protonation of the amino group of 1-deoxymethyl-3-dehydrosphinganine.


phosphatidylcholine 40:6

A 1,2-diacyl-sn-glycero-3-phosphocholine in which the two acyl groups contain forty carbons in total with six double bonds.


phosphatidylcholine (15:0/16:1)

A phosphatidylcholine 31:1 in which the fatty acyl groups at positions 1 and 2 are specified as C15:0 and C16:1 respectively.


A lysophosphatidylcholine 22:5 in which the acyl group at position 1 is (4Z,7Z,10Z,13Z,16Z)-docosapentaenoyl and the hydroxy group at position 2 is unsubstituted.


ambenonium

A symmetrical oxalamide-based bis-quaternary ammonium ion having ethyl and 2-chlorobenzyl groups attached to the nitrogens.


An alpha-amino-acid cation obtained by deprotonation of the carboxy group and protonation of the amino groups of 4-hydroxy-L-lysine: major species at pH 7.3.


A quadruply-charged organic cation arising from protonation of the four amino groups of 2'-oxokanamycin A; major species at pH 7.3.


octopaminium

The conjugate acid of octopamine; major species at pH 7.3.


A sphingomyelin 34:0 in which the N-acyl group and sphingoid base are specified as hexadecanoyl and sphinganine respectively.


A phosphatidylcholine 24:0 in which the acyl groups specified at positions 1 and 2 are tridecanoyl and undecanoyl respectively.


quaternary ammonium ion

A derivative of ammonium, NH4(+), in which all four of the hydrogens bonded to nitrogen have been replaced with univalent (usually organyl) groups.


A secondary amino compound that is 4-(2-aminoethyl)-2,5-dimethoxybenzonitrile in which one of the hydrogens of the amino group has been replaced by a 2-hydroxybenzyl group. A 5-hydroxytryptamine 2A receptor agonist.


Stage IIIB Cervical Cancer FIGO 2018

category: biolink:Disease biolink:DiseaseOrPhenotypicFeature biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing

description: Cervical carcinoma with extension to the pelvic wall and/or hydronephrosis or nonfunctioning kidney (unless known to be due to another cause). (FIGO 2018)


name: regulation of steroid biosynthetic process

category: biolink:BiologicalProcess biolink:Occurrent biolink:OntologyClass biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus.


name: positive regulation of sterol biosynthetic process

description: Any process that activates or increases the frequency, rate or extent of a sterol biosynthetic process.


name: negative regulation of sterol biosynthetic process

description: Any process that stops, prevents or reduces the frequency, rate or extent of a sterol biosynthetic process.


name: negative regulation of cholesterol biosynthetic process

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cholesterol.


name: negative regulation of androgen biosynthetic process

description: Any process that stops, prevents, or reduces the frequency, rate or extent of androgen biosynthetic process.


name: positive regulation of steroid biosynthetic process

description: Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus.


name: regulation of sterol biosynthetic process

description: Any process that modulates the frequency, rate or extent of a sterol biosynthetic process.


name: negative regulation of steroid biosynthetic process

description: Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus.


name: positive regulation of cholesterol biosynthetic process

description: Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cholesterol.


An optically active form of 3-ammonio-3-phenylpropanoate having (S)-configuration.


Leaflet Disruption Due To Calcification

description: The disturbance of a cusp of a heart valve secondary to the accumulation of calcium on the valve tissue. This most often results in stenosis of the valve.


Leaflet Disruption

description: The disturbance of a cusp of a heart valve, often resutling in dysfunction of the valve.


Leaflet Disruption Due To Infection

description: The disturbance of a cusp of a heart valve secondary to infection affecting the valve tissue, which can result in valvular dysfunction.


Leaflet Disruption Due To Unknown Cause

description: The disturbance of a cusp of a heart valve without an identifiable cause.


name: Leaflet Disruption Due To Host Tissue Overgrowth

description: The disturbance of a cusp of a heart valve secondary to an increase in tissue mass at the valve site, which can lead to valve dysfunction. This often happens as a result of fibrosis of tissue surrounding the suture line of a prosthetic valve.


name: Leaflet Disruption Due To Suture Abrasion

description: The disturbance of a cusp of a heart valve secondary to irritation by surgical sutures, which can result in valvular dysfunction.


Vulvar Fibroadenoma

description: A benign epithelial-stromal neoplasm that arises from the vulva and resembles the breast fibroadenoma.


name: Fibroadenoma of Anogenital Mammary-Type Glands

description: A benign epithelial-stromal neoplasm that arises from the perineum and resembles the breast fibroadenoma.


Anal Fibroadenoma

description: A benign epithelial-stromal neoplasm that arises from the anus and resembles the breast fibroadenoma.


ETHYL VANILLIN

A member of the class of benzaldehydes that is vanillin in which the methoxy group is replaced by an ethoxy group.


name: Esophageal Squamous Intraepithelial Neoplasia

description: A lesion in which the architectural and cytologic abnormalities involve either the lower or both the lower and the upper half of the esophageal squamous epithelium.


name: High Grade Esophageal Squamous Intraepithelial Neoplasia

description: A lesion in which the architectural and cytologic abnormalities involve both the lower and the upper half of the esophageal squamous epithelium.


name: Low Grade Esophageal Squamous Intraepithelial Neoplasia

description: A lesion in which the architectural and cytologic abnormalities are confined to the lower half of the esophageal squamous epithelium.


name: Extramedullary Disease in Multiple Myeloma Involving the Liver

description: Infiltration of the hepatic sinusoids by malignant (clonal) plasma cells in patients with history of multiple myeloma.


L-ARABINOSE

A L-arabinopyranose with an alpha-configuration at the anomeric position.


ganglioside GM2 (24:1)

A sialotriaosylceramide that is N-acetyl-beta-D-galactosaminyl-(1->4)-alpha-N-acetylneuraminosyl-(2->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-N-acylsphingosine in which the acyl group on the sphingosine nitrogen is tetracos-15-enoyl. A constituent of natural ganglioside GM2.


fisetin 8-C-glucoside

A  flavone C-glycoside that is fisetin substituted by a beta-D-glucopyranosyl residue at position 8 via a C-glycosidic linkage.


A 5-HETrE consisting of (6E,8Z,11Z)-icosatrienoic acid in which the 5-hydroxy group has S-configuration.


GALLOCATECHIN

A gallocatechin  that has (2R,3S)-configuration. It is found in green tea and bananas.


name: Unresectable Diffuse Midline Glioma, H3 K27M-Mutant

description: Diffuse midline glioma, H3 K27M-mutant that is not amenable to surgical resection.


Unresectable Diffuse Midline Glioma

description: Diffuse midline glioma that is not amenable to surgical resection.


name: atrazine catabolic process to cyanuric acid

description: The chemical reactions and pathways resulting in the breakdown of atrazine, a triazine ring-containing herbicide, into cyanuric acid.


The alpha-stereoisomer of isoorientin 2''-O-rhamnoside . It has been isolated from Petrorhagia velutina.


CTPB

A benzamide obtained by formal condensation of the carboxy group of 2-ethoxy-6-pentadecylbenzoic acid with one of the amino groups of 4-chloro-3-(trifluoromethyl)aniline.


tamsulosin

A 5-(2-{[2-(2-ethoxyphenoxy)ethyl]amino}propyl)-2-methoxybenzenesulfonamide that has (R)-configuration. A specific alpha1 adrenoceptor antagonist used (generally as its hydrochloride salt, tamsulosin hydrochloride) in the treatment of prostatic hyperplasia, chronic prostatitis, urinary retention, and help with the passage of kidney stones.


A secondary amino compound that is ammonia in which nitrogen is substituted by a 1-(4-methoxy-3-sulfamoylphenyl)propan-2-yl group and a 2-(2-ethoxyphenoxy)ethyl group.


ent-tamsulosin

A 5-(2-{[2-(2-ethoxyphenoxy)ethyl]amino}propyl)-2-methoxybenzenesulfonamide that has (S)-configuration. The enantiomer of tamsulosin.


name: Stage IIIA Gastric Gastrointestinal Stromal Tumor

description: Stage IIIA includes: T3, N0, M0, Mitotic rate: High. T3: Tumor more than 5 cm, but not more than 10 cm, in greatest dimension. N0: No regional lymph node metastasis.  M0: No distant metastasis. (AJCC 7th ed.)


glutamate receptor clustering

description: The neurotransmitter-gated ion channel clustering process in which glutamate receptors are localized to distinct domains in the cell membrane.


receptor clustering

description: The receptor metabolic process that results in grouping of a set of receptors at a cellular location, often to amplify the sensitivity of a signaling response.


name: gamma-aminobutyric acid receptor clustering

description: The receptor clustering process in which gamma-aminobutyric acid (GABA) receptors are localized to distinct domains in the cell membrane.


name: ciliary receptor clustering involved in smoothened signaling pathway

description: Grouping of smoothened or patched receptors in a cilium, contributing to the smoothened signaling pathway.


name: skeletal muscle acetylcholine-gated channel clustering

description: The accumulation of acetylcholine-gated cation channels in a narrow, central region of muscle fibers, in apposition to nerve terminals.


name: neurexin clustering involved in presynaptic membrane assembly

description: The receptor clustering process involved in assembly of the presynaptic membrane in which neurexins are localized to distinct domains in the cell membrane. Neurexins are synaptic cell surface proteins which act as cell recognition molecules at nerve terminals.


name: neuroligin clustering involved in postsynaptic membrane assembly

description: The receptor clustering process involved in assembly of the postsynaptic membrane in which neuroligins are localized to distinct domains in the cell membrane. Neuroligins are neuronal cell surface proteins on the postsynaptic membrane that mediate synapse formation between neurons.


NMDA glutamate receptor clustering

description: The receptor clustering process in which N-methyl-D-aspartate (NMDA) receptors are localized to distinct domains in the cell membrane.


AMPA glutamate receptor clustering

description: The glutamate receptor clustering process in which alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors are localized to distinct domains in the cell membrane.


glycine receptor clustering

description: The receptor clustering process in which glycine receptors are localized to distinct domains in the cell membrane.


name: neurotransmitter-gated ion channel clustering

description: The receptor clustering process in which neurotransmitter-gated ion channels are localized to distinct domains in the cell membrane.


L-proline betaine biosynthetic process

description: The chemical reactions and pathways resulting in the formation of stachydrine, N-methylproline methylbetaine, the betaine derivative of L-proline.


snRNA processing

description: Any process involved in the conversion of a primary small nuclear RNA (snRNA) transcript into a mature snRNA molecule. The primary function of snRNAs is processing pre-messenger RNA in the nucleus. They have also been shown to aid in the regulation of transcription factors (7SK RNA) or RNA polymerase II (B2 RNA), and maintaining the telomeres.


U1 snRNA 3'-end processing

description: Any process involved in forming the mature 3' end of a U1 snRNA molecule.


U4 snRNA 3'-end processing

description: Any process involved in forming the mature 3' end of a U4 snRNA molecule.


U2 snRNA 3'-end processing

description: Any process involved in forming the mature 3' end of a U2 snRNA molecule.


snRNA 3'-end processing

description: Any process involved in forming the mature 3' end of an snRNA molecule.


name: snRNA 2,2,7-trimethylguanosine (TMG) capping

description: The sequence of enzymatic reactions by which a 2,2,7-trimethylguanosine cap structure is added to the 5' end of an snRNA. The snRNA capping process includes the formation of 7-methyl-G caps found on all RNA polymerase II transcripts, followed by hypermethylation at the 2' position of the guanosine residue to convert a mono-methylated cap to a 2,2,7-trimethylguanosine cap structure. Note that the pol III transcribed U6 snRNA is also TMG capped.


U6 snRNA 3'-end processing

description: Any process involved in forming the mature 3' end of a U6 snRNA molecule.


response to host iron concentration

description: Any process that results in a change in state or activity of the symbiont or its cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detecting iron concentration in its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.


name: aromatic primary alcohol biosynthetic process

description: The chemical reactions and pathways resulting in the formation of aromatic primary alcohol.


cis-golgicide A

A racemate comprising equimolar amounts of (3aR,4S,9bS)- and (3aS,4R,9bR)-golgicide A. Commercially available golgicide A is a 10:1 mixture of cis- and trans-golgicide A; the (3aS,4R,9bR) stereoisomer is the most active.


Hemangioendothelioma, benign

description: A benign vascular proliferation characterized by the presence of prominent endothelial cells and the formation of vascular channels.


A tricarboxylic acid that is the 2-oxo derivative of homocitric acid.


A 2-hydroxy-4-oxobutane-1,2,4-tricarboxylic acid that has S configuration.


alvaradoin K

A C-glycosyl compound that is 1,8-dihydroxy-3-methylanthracen-9(10H)-one substituted by a 2-O-senecioyl-alpha-lyxopyranosyl moiety at position 10 via a C-glycosidic linkage  (the 10R stereoisomer). It is isolated from the leaves of Alvaradoa haitiensis and exhibits cytotoxicity against human oral epidermoid carcinoma.


name: Entner-Doudoroff pathway through gluconate to D-glyceraldehyde-3-phosphate

description: The Entner-Doudoroff pathway that proceeds through a D-gluconate intermediate and yields pyruvate and D-glyceraldehyde-3-phosphate.


Entner-Doudoroff pathway

description: A cellular carbohydrate catabolic process that converts a carbohydrate to pyruvate and either glyceraldehyde or glyceraldehyde-3 phosphate by dehydration and aldol cleavage via a gluconate or 6-phosphogluconate intermediate.


name: Entner-Doudoroff pathway through gluconate

description: The Entner-Doudoroff pathway that proceeds through a D-gluconate intermediate.


name: Entner-Doudoroff pathway through gluconate to D-glyceraldehyde

description: The Entner-Doudoroff pathway that proceeds through a D-gluconate intermediate and yields pyruvate and D-glyceraldehyde.


name: Entner-Doudoroff pathway through 6-phosphogluconate

description: A pathway that converts a carbohydrate to pyruvate and glyceraldehyde-3 phosphate by producing 6-phosphogluconate and then dehydrating it.


A linear amino tetrasaccharide comprised of alpha-L-fucosyl, beta-D-galactosyl, N-acetyl-beta-D-glucosaminyl and N-acetyl-alpha-D-galactosamine residues linked sequentially (1->2), (1->4) and (1->3).


name: Stage IIIA Rectal Neuroendocrine Tumor AJCC v8

description: Stage IIIA includes: T4, N0, M0. T4: Tumor invading the visceral peritoneum (serosa) or other organs or adjacent structures. N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 8th ed.)


name: Colorectal Neuroendocrine Tumor by AJCC v8 Stage

description: A term that refers to the staging of a colorectal neuroendocrine tumor, following the rules of the TNM AJCC v8 classification system. This staging system applies to colorectal "carcinoid" tumors (neuroendocrine tumor G1 and G2, and rare-well differentiated G3). High-grade neuroendocrine carcinomas and mixed adenoneuroendocrine carcinomas of the colon and rectum are not staged using this staging system. (from AJCC 8th Ed.)


name: Stage I Colorectal Neuroendocrine Tumor AJCC v8

description: Stage I includes: T1, N0, M0. T1: Tumor invading the lamina propria or submucosa and measuring 2 cm or less. N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 8th ed.)


name: Stage IIB Colon Neuroendocrine Tumor AJCC v8

description: Stage IIB includes: T3, N0, M0. T3: Tumor invading through the muscularis propria into subserosal tissue without penetration of overlying serosa. N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 8th ed.)


name: Stage IIB Rectal Neuroendocrine Tumor AJCC v8


name: Stage IIIB Colon Neuroendocrine Tumor AJCC v8

description: Stage IIIB includes: (T1, N1, M0); (T2, N1, M0); (T3, N1, M0); (T4, N1, M0). T1: Tumor invading the lamina propria or submucosa and measuring 2 cm or less. T2: Tumor invading the muscularis propria or measuring more than 2 cm with invasion of the lamina propria or submucosa. T3: Tumor invading through the muscularis propria into subserosal tissue without penetration of overlying serosa. T4: Tumor invading the visceral peritoneum (serosa) or other organs or adjacent structures. N1: Regional lymph node metastasis. M0: No distant metastasis. (AJCC 8th ed.)


name: Stage IIIB Rectal Neuroendocrine Tumor AJCC v8


name: Rectal Neuroendocrine Tumor by AJCC v8 Stage

description: A term that refers to the staging of a rectal neuroendocrine tumor, following the rules of the TNM AJCC v8 classification system. This staging system applies to rectal "carcinoid" tumors (neuroendocrine tumor G1 and G2, and rare-well differentiated G3). High-grade neuroendocrine carcinomas and mixed adenoneuroendocrine carcinomas of the rectum are not staged using this staging system. (from AJCC 8th Ed.)


name: Stage IIB Colorectal Neuroendocrine Tumor AJCC v8


name: Stage IIA Colorectal Neuroendocrine Tumor AJCC v8

description: Stage IIA includes: T2, N0, M0. T2: Tumor invading the muscularis propria or measuring more than 2 cm with invasion of the lamina propria or submucosa. N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 8th ed.)


name: Stage IIA Rectal Neuroendocrine Tumor AJCC v8


name: Colon Neuroendocrine Tumor by AJCC v8 Stage

description: A term that refers to the staging of a colon neuroendocrine tumor, following the rules of the TNM AJCC v8 classification system. This staging system applies to colon "carcinoid" tumors (neuroendocrine tumor G1 and G2, and rare-well differentiated G3). High-grade neuroendocrine carcinomas and mixed adenoneuroendocrine carcinomas of the colon are not staged using this staging system. (from AJCC 8th Ed.)


name: Stage IIIB Colorectal Neuroendocrine Tumor AJCC v8


name: Stage I Colon Neuroendocrine Tumor AJCC v8


name: Stage IIIA Colon Neuroendocrine Tumor AJCC v8


name: Stage IIA Colon Neuroendocrine Tumor AJCC v8


name: Stage IIIA Colorectal Neuroendocrine Tumor AJCC v8


A heparin hexasaccharide consisting of 4-deoxy-2-O-sulfo-alpha-L-threo-hex-4-enopyranuronosyl, 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranosyl, alpha-L-idopyranuronosyl, 2-acetamido-2-deoxy-6-O-sulfo-alpha-D-glucopyranosyl, beta-D-glucopyranuronosyl, and 2-deoxy-3,6-di-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose units joined in sequence by 1->4 linkages. Sequence: DUA2S-GlcNS6S-IdoA-GlcNAc6S-GlcA-GlcNS3S6S.


A steroidal acyl-CoA that results from the formal condensation of the thiol group of coenzyme A with the carboxy group of 12alpha-hydroxy-3-oxochola-4,6-dien-24-oic acid.


An alpha-D-galactoside that is the 2-aminoethyl glycoside of a tetrasaccharide consisting of beta-D-glucuronosyl, beta-D-glucosyl, alpha-D-glucosyl and alpha-D-galactosyl residues linked sequentially (1->4).


alpha-D-galactoside

Any D-galactoside having alpha-configuration at its anomeric centre.


6-bromo-2-naphthyl alpha-D-galactoside

An alpha-D-galactoside having a 6-bromo-2-naphthyl substituent at the anomeric position.


fagopyritol B1

An alpha-D-galactoside that is 1D-chiro-inositol having an alpha-D-galactosyl residue attached at position 2 via a glycosidic linkage.


An alpha-D-glucoside that is the 2-aminoethyl glycoside of a tetrasaccharide consisting of two beta-D-glucosyl residues, an alpha-D-glucosyl residue and (at the reducing end) an alpha-D-galactosyl residue, all linked sequentially (1->4).


An alpha-D-glucoside that is the 2-aminoethyl glycoside of a pentasaccharide consisting of  alpha-D-galactosyl, beta-D-glucuronosyl, beta-D-glucosyl, alpha-D-glucosyl and alpha-D-galactosyl residues, all linked sequentially (1->4).


An amino disaccharide that is 2-acetamido-2-deoxy-beta-D-glucopyranose in which the hydroxy group at position 3 has been converted into the corresponding alpha-D-galactopyranoside.


A glycosyl glycoside consisting of two alpha-D-galactopyranose residues joined by a (1->1) glycosidic bond.


A glycosyl glycoside that is alpha-D-galactopyranose in which the anomeric hydroxy group has been converted into the corresponding alpha-D-glucopyranosyl derivative.


A fatty amide resulting from the formal condensation of the carboxy group of cerotic acid with the amino group of (2S,3S,4R)-2-aminononane-1,3,4-triol and in which the primary hydroxy group of the resulting product has been converted to the corresponding alpha-D-galactopyranoside.


A disaccharide that is D-glucopyranose in which the hydroxy group at position 2 has been converted into the corresponding alpha-D-galactopyranoside.


An alpha-D-galactoside having a 4-methylumbelliferyl substituent at the anomeric position


An alpha-D-glucoside that is the 2-aminoethyl glycoside of a hexasaccharide consisting of alpha-D-glucosyl, alpha-D-galactosyl, beta-D-glucuronosyl, beta-D-glucosyl, alpha-D-glucosyl and alpha-D-galactosyl residues, all linked sequentially (1->4).


A disaccharide that is L-fucopyranose in which the hydroxy group at position 4 has been converted into the corresponding alpha-D-galactopyranoside.


adxanthromycin A

An organic peroxide, which is the 3-alpha-D-galactopyranosyl substituted derivative of the dimer obtained by oxidation at the 10-hydroxy position of (10S)-3,8,10-trihydroxy-1,7,10-trimethyl-9-oxo-9,10-dihydroanthracene-2-carboxylic acid. It is isolated from the fermentation broth of Streptomyces.


An amino pentasaccharide consisting of alpha-L-fucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-galactopyranose, and 2-acetamido-2-deoxy-beta-D-glucopyranose joined in sequence by (1->4), (1->3), and (1->4) glycosidic bonds and in which the hydroxy group at position 3 of the non-terminal 2-acetamido-2-deoxy-beta-D-glucopyranose moiety has been to the corresponding alpha-D-galactopyranoside.


4-nitrophenyl alpha-D-galactoside

An alpha-D-galactopyranoside having a 4-nitrophenyl substituent at the anomeric position.


An alpha-D-Galp-(1->4)-D-Glcp in which the carbon bearing the anomeric hydroxy group has beta configuration.


A carboxylic ester obtained by formal condensation of 9-(alpha-D-galactosyloxy)nonanoic acid and methanol.


A alpha-D-Galp-(1->4)-D-Glcp in which the carbon bearing the anomeric hydroxy group has alpha configuration.


isofloridoside

A galactosylglycerol that is glycerol in which one of the primary hydroxy groups has been converted into the corresponding alpha-D-galactopyranoside.


A isofloridoside in which position 2 of the glyceryl moiety has R configuration.


A glycosylglucose that is D-glucopyranose in which the hydroxy group at position 4 has been converted into the corresponding alpha-D-galactoside.


A cyclitol ether that is D-myo-inositol carrying methyl and alpha-D-galactosyl substituents at positions 4 and 3 respectively.


A disaccharide that is D-mannitol in which the hydroxy group at position 2 has been converted into its alpha-D-galactopyranoside


An alpha-D-glucoside that is the 2-aminoethyl glycoside of a trisaccharide consisting of  beta-D-glucosyl, alpha-D-glucosyl and alpha-D-galactosyl residues linked sequentially (1->4).


An alpha-D-Galp-(1->2)-D-Glcp in which the carbon bearing the anomeric hydroxy group has alpha configuration.


An amino disaccharide that is 2-acetamido-beta-D-glucopyranose in which the hydroxy group at position 6 has been glycosylated by an alpha-D-galactopyranosyl group.


An alpha-D-galactoside having a 1D-myo-inositol substituent at the anomeric position.


fagopyritol A1

An alpha-D-galactoside having a 1D-chiro-inositol substituent at the anomeric position.


nitrogen

An elemental molecule consisting of two trivalently-bonded nitrogen atoms.


A hexaarabinofuranosyl group corresponding to part of the arabinogalactan portion of the lipoarabinomannan from Mycobacterium tuberculosis.


A secondary fatty alcohol that is tetradecane substituted by a hydroxy group at position 6.


N(4)-methyl-dCMP(1-) residue

An organic anionic group obtained by deprotonation of the phosphate OH group of an N(4)-methyl-dCMP residue; major species at pH 7.3.


A polysaccharide derivative composed of a backbone of linear tetrasaccharide derivative repeating units consisting of beta-QuiN4Fm-(1->4)-alpha-GalNAcAN-(1->4)-alpha-GalNAcAN-(1->3)-beta-QuiNAc connected by beta-(1->2) linkages.


A dTDP-sugar having 3,4-didehydro-2,6-dideoxy-alpha-D-glucose as the sugar component.


An amino acid zwitterion resulting from the transfer of a proton from the carboxy to the side-chain amino group of any N(2)-[(3R)-hydroxy-acyl]-L-ornithine; major species at pH 7.3.


A dicarboxylic acid monoamide obtained by formal condensation of the 6-amino group of 2,6-diaminobenzimidazole with one of the carboxy groups of glutaric acid.


adenosine biosynthetic process

description: The chemical reactions and pathways resulting in the formation of adenosine, adenine riboside, a ribonucleoside found widely distributed in cells of every type as the free nucleoside and in combination in nucleic acids and various nucleoside coenzymes.


adenosine salvage

description: Any process that generates adenosine, adenine riboside, from derivatives of it without de novo synthesis.


name: cellulose catabolism by endo-processive cellulases

description: The breakdown into simpler components of cellulose. Catabolism is initiated by endohydrolytic attacks on the cellulose chain, and the resulting pieces are further degraded by cellulase enzymes to produce smaller and smaller fragments.


beta-glucan catabolic process

description: The chemical reactions and pathways resulting in the breakdown of beta-glucans.


anaerobic cellulose catabolic process

description: The chemical reactions and pathways resulting in the breakdown of cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation, in absence of oxygen.


(1->3)-beta-D-glucan catabolic process

description: The chemical reactions and pathways resulting in the breakdown of (1->3)-beta-D-glucans.


(1->6)-beta-D-glucan catabolic process

description: The chemical reactions and pathways resulting in the breakdown of (1->6)-beta-D-glucans.


cellulose catabolic process

description: The chemical reactions and pathways resulting in the breakdown of cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation.


triphenylmethane

A triarylmethane in which the three aryl groups are phenyl. It forms the basic skeleton of several synthetic dyes.


triarylmethane

Any benzenoid aromatic compound containing three aryl groups connected by a single C atom.


name: Head and Neck Phosphaturic Mesenchymal Tumor

description: A phosphaturic mesenchymal tumor that arises from the head and neck. It usually affects the paranasal sinuses. The head and neck region is the most frequently involved site for phosphaturic mesenchymal tumors, following the appendicular skeleton.


name: Appendicular Skeleton Phosphaturic Mesenchymal Tumor

description: A phosphaturic mesenchymal tumor that arises from the appendicular skeleton. The appendicular skeleton is the most frequently involved site for phosphaturic mesenchymal tumors.


name: Malignant phosphaturic mesenchymal tumor

description: A phosphaturic mesenchymal tumor characterized by the presence of nuclear atypia, high mitotic activity, increased cellularity, marked pleomorphism, and necrosis. It usually develops in lesions that have recurred locally and metastasizes to other sites.


A member of the class of 2,6-diaminopurines that is 9H-purine in which the hydrogens at positions 2 and 6 are replaced by amino groups.


CLOMAZONE

An isoxazolidinone that is 1,2-oxazolidin-3-one substituted by a 2-chlorobenzyl group at position 2 and two methyl groups at position 4.


A FAHFA obtained by formal condensation of the carboxy group of palmitic acid with the hydroxy group of 11-hydroxystearic acid.


A univalent carboacyl group formed by loss of OH from the carboxy group of (3-bromo-4-hydroxy-5-nitrophenyl)acetic acid.


duodenal goblet cell

category: biolink:Cell biolink:AnatomicalEntity biolink:PhysicalEssence biolink:OrganismalEntity biolink:SubjectOfInvestigation biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: A goblet cell that is part of the epithelium proper of duodenum.


duodenum glandular cell

description: Glandular cell of duodenal epithelium. Example: Enterocytes, Goblet cells, enteroendocrine cells; Paneth cells; M cells; Brunner's gland cell.


name: endoplasmic reticulum tubular network formation

description: The aggregation, arrangement and bonding together of a set of components to form the endoplasmic reticulum (ER) tubular network. The ER tubular network is the ER part that comprises the membranes with high curvature in cross-section.


D-glycero-D-manno-heptose 7-phosphate

D-glycero-D-manno-heptose in which the hydrogen of the primary hydroxy group is substituted by a dihydrogen phosphate group.


The 1-alpha-anomer of D-glycero-D-manno-heptose 7-phosphate.


D-glycero-beta-D-manno-heptose in which the hydrogens of the hydroxy groups at positions 1 and 7 are substituted by dihydrogen phosphate groups.


Dianion of D-glycero-D-manno-heptose 1-phosphate arising from deprotonation of both phosphate OH groups.


D-glycero-D-manno-heptose 1-phosphate(2-) with alpha-configuration at the anomeric carbon atom.


D-glycero-D-manno-heptose 1-phosphate(2-) with beta-configuration at the anomeric carbon atom.


D-glycero-alpha-D-manno-heptose in which the hydrogens of the hydroxy groups at positions 1 and 7 are substituted by dihydrogen phosphate groups.


The 1-beta-anomer of D-glycero-D-manno-heptose 7-phosphate.


D-glycero-D-manno-heptose in which the hydrogens of the hydroxy groups at positions 1 and 7 are substituted by dihydrogen phosphate groups.


Conjugate base of bkos#30-CoA


A hydroxyaldehyde that is pentanal carrying three hydroxy substituents at positions 3, 4 and 5.


description: The chemical reactions and pathways resulting in the breakdown of UDP-N-acetylgalactosamine, a substance composed of N-acetylgalactosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate.


description: The chemical reactions and pathways involving UDP-N-acetylgalactosamine, a substance composed of N-acetylgalactosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate.


description: The chemical reactions and pathways resulting in the formation of UDP-N-acetylgalactosamine, a substance composed of N-acetylgalactosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate.


name: Metastatic malignant neoplasm to trachea

description: A malignant neoplasm that has spread to the trachea from another anatomic site.


This is mimetic of 4-Hydroxynonenal (4-HNE) and a potential inhibitor of SIRT2 enzyme


A branched amino heptasaccharide consisting of a chain of four alpha-sialyl residues, a beta-D-galactosyl residue and a beta-D-glucose residue linked sequentially (2->8), (2->8), (2->8), (2->3) and (1->4), to the galactosyl residue of which is also linked (1->4) an N-acetyl-beta-D-galactosaminyl residue.


heptasaccharide derivative

An oligosaccharide derivative that is formally obtained from a heptasaccharide.


A branched amino heptasaccharide comprising N-acetyl-alpha-D-galactosamine, beta-D-galactose, N-acetyl-beta-D-galactosamine, alpha-D-galactose, beta-D-galactose and D-glucose residues linked sequentially (1->3), (1->3), (1->3), (1->4) and (1->4), to the beta-D-galactose residue nearest to the non-reducing end is also linked (1->2) an alpha-L-fucose residue.


A branched amino heptasaccharide in which a tetrasaccharide backbone consisting of beta-D-galactose, N-acetyl-beta-D-glucosamine, beta-D-galactose and  beta-D-glucose residues linked sequentially (1->3), (1->3) and (1->4), the galactose residue at the non-reducing end of which carries via a (1->6) linkage a trisaccharide side-chain comprising N-acetyl-alpha-neuraminyl, beta-D-galactose and N-acetyl-beta-D-glucosamine residues linked (2->6) and (1->4).


A branched amino heptasaccharide consisting of a linear pentasaccharide chain of N-acetyl-beta-D-glucosamine, beta-D-galactose, beta-D-glucose, L-glycero-alpha-D-manno-heptose (Hep) and 3-deoxy-D-manno-oct-2-ulose (Kdo) residues linked in a (1->3), (1->4), (1->4), (1->5) sequence, to the Hep residue of which is linked (1->3) an N-acetyl-alpha-D-glucosaminyl-(1->2)-L-glycero-alpha-D-manno-heptosyl side-chain. lpt3 and and lgtB mutant of the core oligosaccharide of Neisseria meningitidis.


A branched amino heptasaccharide that is beta-D-Manp-(1->4)-beta-D-GlcpNAc-(1->4)-beta-D-GlcpNAc in which the hydroxy groups at positions 2 and 3 of the mannosyl residue have been glycosylated by a beta-D-xylopyranosyl residue and an N-acetyl-beta-D-glucopyranosaminyl-(1->2)-alpha-D-mannopyranosyl group respectively, while the GlcNAc residue at the reducing end carries also an alpha-L-fucosyl residue attached via a (1->3)-linkage.


GlyTouCan G08691QG

A composition-only glycan consisting of four hexosyl groups, one acetaminohexosyl group and two 6-deoxyhexosyl groups (identities and connectivity unknown). Composition: Hex4 HexNAc1 dHex2.


GlyTouCan G00406II

A composition-only glycan consisting of four hexosyl groups, two acetaminohexosyl groups, and one 6-deoxyhexosyl group (identities and connectivity unknown). Composition: Hex4 HexNAc2 dHex1.


A branched amino heptasaccharide derivative that is alpha-D-Man-(1->3)-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc in which the beta-D-GlcNAc residue carries an alpha-L-Fuc residue via a (1->3) linkage and the the D-GlcNAc residue at the reducing end carries two alpha-L-Fuc residues via (1->3) and (1->6) linkages.


amino heptasaccharide

A heptasaccharide derivative having one or more substituted or unsubstituted amino groups in place of hydroxy groups at unspecified positions.


A member of the class of neuraminic acids that is neuraminic acid attached in sequence to beta-D-galactopyranosyl, 2-acetamido-2-deoxy-beta-D-glucopyranosyl, beta-D-galactopyranosyl, and beta-D-glucopyranosyl, residues by (2->3), (1->3), (1->3) and (1->4) glycosidic linkages. The galactosyl residue attached to the neuraminic acid is glycosylated at position 4 by a beta-D-acetamidogalactosyl residue, while the other galactosyl residue has been glycosylated at position 4 by a 2-acetamido-beta-D-galactopyranosyl residue.


A branched amino heptasaccharide consisting of a sequence of beta-D-galactose, N-acetyl-beta-D-glucosamine, alpha-D-mannose, beta-D-mannose and two N-acetyl-beta-D-glucosamine residues linked (1->4), (1->2), (1->6), (1->4) and (1->4), with an alpha-D-mannose linked (1->3) to the beta-D-mannose residue.


A branched amino heptasaccharide consisting of a linear pentasaccharide chain of alpha-sialyl, beta-D-galactose, N-acetyl-beta-D-glucosamine, beta-D-galactose and D-glucose residues linked sequentially (2->6), (1->3), (1->3) and (1->4), to the galactose residue nearest to the reducing end is also linked (1->6) a beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl disaccharide unit.


A linear amino heptasaccharide comprising alpha-neuraminyl, beta-D-galactosyl, N-acetyl-beta-D-glucosaminyl, beta-D-galactosyl, N-acetyl-beta-D-glucosaminyl, beta-D-galactosyl and N-acetyl-beta-D-glucosamine residues connected via (2->3), (1->4), (1->3), (1->4), (1->3) and (1->4) linkages.


An amino heptasaccharide consisting of a beta-D-Gal-(1->3)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc tetrasaccharide backbone, to the galactosyl residue distal to the reducing end is (1->4)-linked a beta-DGlcNAc residue, while Neu5Ac residues are linked to this same galactosyl residue and the GlcNAc residue via (2->3) and (2->6) glycosidic linkages respectively. An antigen for the monoclonal antibody RM2, it is used as a histological marker for prostate cancer.


A branched amino heptasaccharide comprising a linear hexasaccharide chain of alpha-N-acetylneuraminyl, beta-D-galactose, N-acetyl-beta-D-glucosamine, beta-D-galactose, N-acetyl-beta-D-glucosamine and N-acetyl-alpha-D-galactosamine residues linked sequentially (2->6), (1->4), (1->3), (1->4), (1->6), to the N-acetyl-alpha-D-galactosamine residue at the reducing end of which is also linked (1->3) a further beta-D-galactose residue.


A linear amino heptasaccharide comprising alpha-sialyl, beta-D-galactosyl, N-acetyl-beta-D-glucosaminyl, beta-D-galactosyl, N-acetyl-beta-D-glucosaminyl, beta-D-galactosyl and N-acetyl-beta-D-glucosamine residues in a (2->6), (1->4), (1->3), (1->4), (1->3) and (1->4) sequence.


GlyTouCan G05194RK

A composition-only glycan consisting of three hexosyl groups, two acetaminohexosyl groups and two N-acetyl-neuraminic acid group (identities and connectivity unknown). Composition: Hex3 HexNAc2 NeuAc2.


A branched amino heptasaccharide consisting of N-acetyl-alpha-D-galactosamine carrying two individual N-acetyl-alpha-neuraminyl-(2->6)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosyl tetrasaccharide units via (1->3) and (1->6) glycosidic linkages.


An amino heptasaccharide in which two alpha-L-fucosyl-(1->2)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl chains are linked (1->3) and (1->6) to D-galactose.


A branched amino heptasaccharide consisting of a beta-D-GlcNAc residue at the reducing end with an alpha-D-Man-(1->3)-[beta-D-Xyl-(1->2)]-beta-D-Man-(1->4)-beta-D-GlcNAc moiety attached via a (1->4) linkage and alpha-L-Fuc residues attached via (1->3) and (1->6) linkages.


A branched amino heptasaccharide derivative that is beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc in which the mannosyl group is substituted at position 3 by a beta-D-GlcNAc-(1->2)-alpha-D-Man group and at position 6 by an alpha-D-Man-(1->6)-alpha-D-Man group.


A branched amino heptasaccharide consisting of a beta-D-GlcNAc residue at the reducing end with a beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)-[alpha-D-Man-(1->3)]-[beta-D-Xyl-(1->2)]-beta-D-Man-(1->4)-beta-D-GlcNAc moiety attached via a beta-(1->4)-linkage.


A branched heptasaccharide derivative consisting of three sialyl residues, two galactose residues, one N-acetylglucosamine and a glucose residue at the reducing end. The oligosaccharide of ganglioside GT1a.


A branched amino heptasaccharide consisting of alpha-D-mannose,  beta-D-mannose and two N-acetyl-beta-D-glucosamine residues linked sequentially (1->6), (1->4) and (1->4), to the alpha-D-mannose residue of which are linked (1->3) and (1->6) two further alpha-D-mannose residues and to the beta-D-mannose residue of which is (1->3)-linked also an alpha-D-mannose residue.


A branched amino heptasaccharide derivative that is beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc in which the mannosyl group is substituted at position 3 by a beta-D-GlcNAc-(1->2)-alpha-D-Man group and at position 6 by an alpha-D-Man-(1->6)-alpha-D-Man group.


A branched amino heptasaccharide consisting of a hexasaccharide backbone comprising alpha-D-galactosyl, beta-D-galactosyl, N-acetyl-beta-D-galactosaminyl,alpha-D-galactosyl, beta-D-galactosyl and (at the reducing end) D-glucose residues linked sequentially (1->3), (1->3), (1->3), (1->4) and (1->4), to the D-galactosyl residue proximal to the non-reducing end is also linked (1->2) an alpha-L-fucosyl residue.


An amino heptasaccharide consisting of two N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannose disaccharide units linked (1->3) and (1->6) to the mannose residue of a beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-glucosamine trisaccharide. The anomer of beta-D-GlcpNAc-(1->2)-alpha-D-Manp-(1->3)-[beta-D-GlcpNAc-(1->2)-alpha-D-Manp-(1->6)]-beta-D-Manp-(1->4)-beta-GlcpNAc-(1->4)-D-GlcpNAc in which the configuration at the anomeric centre of the reducing-end N-acetyl-D-glucosamine residue is beta.


A branched amino heptasaccharide derivative that is beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc in which the mannosyl group is substituted at position 3 by a beta-D-GlcNAc-(1->2)-alpha-D-Man group and at position 6 by an alpha-D-Man residue, while the D-GlcNAc residue at the reducing end is substituted at position 6 by an alpha-L-Fuc residue.


A branched amino heptasaccharide consisting of three sialyl residues, two galactose residues, one N-acetylglucosamine and a glucose residue at the reducing end.


A branched amino heptasaccharide derivative that is beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc in which the mannosyl group is substituted at position 3 by a beta-D-GlcNAc-(1->2)-[beta-D-GlcNAc-(1->6)]-alpha-D-Man group and the GlcNAc residue at the reducing end is substituted at position 6 by an alpha-L-Fuc residue.


A branched amino heptasaccharide consisting of a linear sequence of N-acetyl-alpha-neuraminyl, beta-D-galactosyl, N-acetyl-beta-D-glucosaminyl, beta-D-galactosyl and N-acetyl-beta-D-glucosamine residues linked respectively (2->3), (1->3), (1->3) and (1->4), to each N-acetyl-beta-D-glucosamine residue of which is also linked (1->4) an alpha-L-fucosyl residue.


A branched amino heptasaccharide comprised of a backbone of beta-D-galactosyl, N-acetyl-beta-D-glucosaminyl, alpha-D-mannosyl, beta-D-mannosyl, N-acetyl-beta-D-glucosaminyl and N-acetyl-beta-D-glucosamine residues linked in sequence (1->4), (1->2), (1->3), (1->4) and (1->4), to the beta-D-mannosyl residue is also linked (1->2) a beta-D-xylosyl residue.


A linear amino heptasaccharide comprising N-acetyl-beta-D-glucosamine at the reducing end with an N-acetyl-beta-D-glucosaminyl-(1->4)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl moiety at the 4-position.


A branched amino heptasaccharide compound consisting of a beta-D-GlcNAc residue at the reducing end with an alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc moiety attached via a (1->4)-linkage and two alpha-L-Fuc residues attached via (1->3)- and (1->6)-linkages.


An amino heptasaccharide in which two alpha-L-fucosyl-(1->2)-beta-D-galactosyl-(1->3)-N-acetyl-beta-D-glucosaminyl chains are linked (1->3) and (1->6) to alpha-D-galactose.


A heptasaccharide derivative in which a backbone of one glucuronic acid, one 6-O-acetyl and three mannose residues is branched at each of the two non-terminal mannoses with a xylose residue, linked alpha(1->2).


A branched amino heptasaccharide derivative that is beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc in which the beta-GlcNAc residue distal to the reducing end carries an alpha-L-Fuc residue via a (1->3) linkage and the GlcNAc residue at the reducing end carries an alpha-L-Fuc residue via a (1->6) linkage.


An amino hexasaccharide that is the carbohydrate portion of ganglioside GalNAc-GD1a.


A branched amino heptasaccharide consisting of a linear pentasaccharide comprising N-acetyl-alpha-neuraminic acid, beta-D-galactose, two L-glycero-alpha-D-manno-heptose (L-alpha-D-Hep) residues and a 3-deoxy-alpha-D-manno-oct-2-ulose (alpha-Kdo) residue linked in sequence (2->3), (1->3),(1->3), (1->3) and (1->5), to the L-alpha-D-Hep residue proximal to the reducing end is also linked (1->4) a beta-D-glucose residue, while the alpha-Kdo residue also carries a second alpha-Kdo residue linked (2->-4). One of a number of chemoenzymatically synthesised oligosaccharides composed of the inner core oligosaccharide of Campylobacter jejuni extended by various ganglioside mimics.


GlyTouCan G05645NK

A composition-only glycan consisting of six hexosyl groups and one acetaminohexosyl group (identities and connectivity unknown). Composition: Hex6 HexNAc1.


A member of the class of neuraminic acids that is neuraminic acid attached in sequence to beta-D-galactopyranosyl, 2-acetamido-2-deoxy-beta-D-glucopyranosyl, beta-D-galactopyranosyl, 2-acetamido-2-deoxy-beta-D-glucopyranosyl, beta-D-galactopyranosyl, and beta-D-glucopyranose units by (2->3), (1->4), (1->3), (1->4), 1->3), and (1->4) glycosidic linkages, respectively.


GlyTouCan G04371QE

A composition-only glycan consisting of four hexosyl groups, two acetaminohexosyl groups and one N-acetyl-neuraminic acid group (identities and connectivity unknown). Composition: Hex4 HexNAc2 NeuAc1.


A branched heptasaccharide derivative consisting of a backbone of four alpha-D-mannose residues linked sequentially (1->3), with the residues at the non-reducing end and at the one proximal to the residue at the reducing end acetylated at O-6, and with a beta-D-glucuronosyl residue and two beta-D-xylosyl residues linked (1->2) to the main chain as shown in the diagram. One of a number of synthetic oligosaccharides used to create a synthetic strategy to Cryptococcus neoformans glucuronoxylomannan (GXM) capsular polysaccharide part structures.


A branched amino heptasaccharide consisting of a linear chain of an alpha-D-mannose residue, a beta-D-mannose residue and two N-acetyl-beta-D-glucosamine residues linked sequentially (1->6), (1->4) and (1->4), to the alpha-D-mannose residue of which are linked (1->3) and (1->2) alpha-D-mannose and beta-D-xylose residues respectively, while the N-acetyl-beta-D-glucosamine residue at the reducing end also carries an alpha-L-fucose residue via a (1->3) linkage.  It forms the heptasaccharide portion of the N-glycan phytohemaglutinin (PHA).


A linear amino heptasaccharide comprising a sequence of alpha-sialyl, beta-D-galactosyl, N-acetyl-beta-D-glucosaminyl, alpha-D-mannosyl, beta-D-mannosyl, N-acetyl-beta-D-glucosaminyl and N-acetyl-D-glucosamine residues linked respectively (2->6), (1->4), (1->2), (1->3), (1->4) and (1->4).


A branched heptasaccharide derivative consisting of a GlcNAc residue at the reducing end with a Man-alpha(1->6)-[Xyl-beta(1->2)-Man-alpha(1->3)]-Man-beta(1->4)-GlcNAc moiety attached via a beta-(1->4)-linkage and a Fuc residue attached via an alpha-(1->6)-linkage.


A branched amino heptasaccharide  comprising a beta-D-galactosyl-(1->4)-beta-D-glucose disaccharide, the galactosyl residue of which carries an N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminyl trisaccharide unit and an N-acetyl-alpha-neuraminyl-(2->8)-N-acetyl-alpha-neuraminyl disaccharide unit through (2->4) and (2->3) linkages respectively. It corresponds to the carbohydrate portion of ganglioside GT1b.


A branched amino heptasaccharide consisting of a linear sequence of N-acetyl-alpha-neuraminyl, beta-D-galactosyl, N-acetyl-beta-D-glucosaminyl, beta-D-galactosyl and N-acetyl-beta-D-glucosamine residues linked respectively (2->3), (1->3), (1->3) and (1->3), to each N-acetyl-beta-D-glucosamine residue of which is also linked an alpha-L-fucosyl residue, (1->4)-linked to the reducing-end residue and (1->3)-linked to the mid-chain one.


A linear amino heptasaccharide comprising a sequence of alpha-sialyl, beta-D-galactosyl, N-acetyl-beta-D-glucosaminyl, alpha-D-mannosyl, beta-D-mannosyl, N-acetyl-beta-D-glucosaminyl and N-acetyl-D-glucosamine residues linked respectively (2->6), (1->4), (1->2), (1->6), (1->4) and (1->4).


A branched derivative heptasaccharide consisting of the tetrasaccharide derivative beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-D-glucose where the galactosyl residue at the non-reducing end has alpha-L-fucosyl and N-acetyl-alpha-D-galactosaminyl residues attached at the 2- and 3-positions respectively and the glucosaminyl residue has an alpha-L-fucosyl residue attached at the 3-position.


An aminoheptasaccharide that is the MAN-3 glycan, alpha-D-Manp-(1->3)-[alpha-D-Manp-(1->6)]-beta-D-Manp-(1->4)-beta-D-GlcpNAc-(1->4)-D-GlcpNAc, in which the (1->6) linked mannosyl group has been glycosylated at positions 3 and 6 by alpha-D-mannopyranosyl groups.


A branched amino heptasaccharide consisting of an N-acetyl-alpha-D-galactosamine residue to which are linked via (1->3) and (1->6) linkages two N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl trisaccharide units.


GlyTouCan G99758GD

An aminoheptasaccharide consisting of two hexosyl and five acetaminohexosyl groups (identities and connectivity unknown). Composition: Hex2 HexNAc5.


A branched amino heptasaccharide consisting of a beta-D-GlcNAc residue at the reducing end with a beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-[beta-D-Xyl-(1->2)]-beta-D-Man-(1->4)-beta-D-GlcNAc moiety attached via a beta-(1->4)-linkage.


A heptasaccharide derivative composed of a 5-deoxy-5-(methylsulfanyl)xylofuranose, two mannopyranose and four arabinofuranose residues in an alpha(1->4), alpha(1->2), alpha(1->5), beta(1->2), alpha(1->5) and alpha(1->5) linear sequence.


A branched amino heptasaccharide derivative that is beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc in which the mannosyl group is substituted at position 3 by a beta-D-GlcNAc-(1->2)-alpha-D-Man group and at position 6 by an alpha-D-Man-(1->2)-alpha-D-Man group.


A branched amino heptasaccharide derivative that is beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc in which the mannosyl group is substituted at position 3 by a beta-D-GlcNAc-(1->2)-alpha-D-Man group and at position 6 by an alpha-D-Man residue, while the D-GlcNAc residue at the reducing end is substituted at position 6 by an alpha-L-Fuc residue.


A linear heptasaccharide derivative comprising a fucose residue linked alpha(1->2) to a chain of three beta(1->3)-linked galactosyl-(1->4)-N-acetylglucosamine units.


A branched amino heptasaccharide consisting of a linear tetrasaccharide of beta-D-galactose, N-acetyl-beta-D-galactosamine, beta-D-galactose and beta-D-glucose residues linked sequentially (1->3), (1->4) and (1->4), to the galactose residue proximal to the reducing end is also linked (2->3) an N-acetyl-alpha-neuraminyl-(2->8)-N-acetyl-alpha-neuraminyl-(2->8)-N-acetyl-alpha-neuraminyl trisaccharide side-chain.  The carbohydrate moiety of ganglioside GT1c.


A branched heptasaccharide derivative consisting of a D-GlcNAc residue at the reducing end with an alpha-D-Man-(1->6)-[beta-D-Xyl-(1->2)]-[alpha-D-Man-(1->3)]-beta-D-Man-(1->4)-beta-D-GlcNAc moiety attached via a (1->4)-linkage and an L-Fuc residue attached via an alpha-(1->3)-linkage.


An amino heptasaccharide that is MAN-3 glycan, alpha-D-Manp-(1->3)-[alpha-D-Manp-(1->6)]-beta-D-Manp-(1->4)-beta-D-GlcpNAc-(1->4)-D-GlcpNAc, in which either (a) two hydroxy groups in one of the terminal mannosyl groups have each undergone glycosylation with a molecule of D-mannopyranose, or (b) one of the hydroxy groups has undergone dimannosylation. The position of the additional mannosyl groups is not known. In the structure shown, either two of the R atoms each represent a D-mannopyranosyl group, or one of the R atoms represents a di-D-mannosyl group; all remaining R atoms = H.


GlyTouCan G02815KT

A partially-defined glycan consisting of 5 hexosyl and 2 acetaminohexosyl groups (identities and connectivity unknown). Composition: Hex5 HexNAc2.


A branched amino heptasaccharide derivative that is beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc in which the mannosyl group is substituted at position 3 by a beta-D-GlcNAc-(1->2)-alpha-D-Man group and at position 6 by an alpha-D-Man-(1->2)-alpha-D-Man group.


GlyTouCan G06110VR

An aminoheptasaccharide consisting of five hexosyl and two acetaminohexosyl groups (identities and connectivity unknown). Composition: Hex5 HexNAc2.


A branched heptasaccharide derivative consisting of the tetrasaccharide derivative beta-D-galactosyl-(1->3)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-D-glucose where the galactosyl residue at the non-reducing end has alpha-L-fucosyl and N-acetyl-alpha-D-galactosaminyl residues attached at the 2- and 3-positions respectively and the glucosaminyl residue has an alpha-L-fucosyl residue attached at the 4-position.


An amino heptasaccharide derivative that is beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc in which the mannosyl group is substituted at positions 3 and 6 by beta-D-GlcNAc-(1->2)-alpha-D-Man groups.


A branched amino heptasaccharide comprised of a hexasaccharide chain of beta-D-galactose, N-acetyl-beta-D-glucosamine, alpha-D-mannose, beta-D-mannose, and two N-acetyl-beta-D-glucosamine residues linked sequentially (1->4), (1->2), (1->3), (1->4) and (1->4), to the beta-D-mannose residue of which is (1->6)-linked an alpha-D-mannose residue.


A heptasaccharide derivative corresponding to the core oligosaccharide of the L1 immunotype of Neisseria meningitidis.


An alpha-D-glucoside that is the 5-aminopentyl glycoside of a branched heptasaccharide consisting of alpha-D-glucuronosyl, beta-D-mannosyl, alpha-D-glucosyl, beta-D-glucosyl, beta-D-mannosyl and beta-D-glucosyl residues linked sequentially (1->3), (1->4), (1->3), (1->4) and (1->4), to the mannosyl residue proximal to the reducing end of which has also linked (1->3) to it an alpha-D-glucuronosyl residue. The 5-aminopentyl group at the reducing end is a spacer to enable further conjugation to a carrier protein for immunological studies.


A branched amino heptasaccharide comprising a linear hexasaccharide chain of alpha-N-acetylneuraminyl, beta-D-galactose, N-acetyl-beta-D-glucosamine, beta-D-galactose, N-acetyl-beta-D-glucosamine and N-acetyl-alpha-D-galactosamine residues linked sequentially (2->3), (1->4), (1->3), (1->4), (1->6), to the N-acetyl-alpha-D-galactosamine residue at the reducing end of which is also linked (1->3) a further beta-D-galactose residue.


A branched heptasaccharide derivative consisting of two repeating units of beta-D-Gal-(1->4)-[alpha-L-Fuc-(1->3)]-beta-D-GlcNAc (joined by a (1->3)-linkage) with an alpha-L-fucosyl residue attached at the 2-position of the galactose residue at the non-reducing end.


A branched heptasaccharide consisting of four alpha-D-mannosyl residues, one beta-D-mannosyl residue and two N-acetyl-beta-D-glucosamine residues, one of which at the reducing end is bonded to the the aryl amino group of 2-amino-N-(2-aminoethyl)benzamide.


A branched amino heptasaccharide comprised of a backbone of N-acetyl-beta-D-galactosaminyl, N-acetyl-beta-D-glucosaminyl, alpha-D-mannosyl, beta-D-mannosyl, N-acetyl-beta-D-glucosaminyl and N-acetyl-beta-D-glucosamine residues linked in sequence (1->4), (1->2), (1->3), (1->4) and (1->4), to the beta-D-mannosyl residue is also linked (1->2) a beta-D-xylosyl residue.


GlyTouCan G03666XN

A composition-only glycan consisting of five hexosyl groups, one 2-acetaminohexosyl group and one 6-deoxyhexosyl group (identities and connectivity unknown). Composition: Hex5 HexNAc1 dHex1.


A branched amino heptasaccharide comprised of a backbone of N-acetyl-beta-D-glucosaminyl, alpha-D-mannosyl, beta-D-mannosyl, N-acetyl-beta-D-glucosaminyl and N-acetyl-beta-D-glucosamine residues linked in sequence (1->2), (1->3), (1->4) and (1->4), to the beta-D-mannosyl residue is also linked (1->2) a beta-D-xylosyl residue, while to the N-acetyl-beta-D-glucosamine residue at the reducing end is also linked (1->6) an alpha-L-fucosyl residue.


name: positive regulation of basidiospore formation

description: Any process that activates, maintains or increases the frequency, rate or extent of frequency, rate or extent of basidiospore formation, a process in which a sexually produced fungal spore is formed on a basidium in the fungi basidiomycetes.


name: positive regulation of zygospore formation

description: Any process that activates, maintains or increases the frequency, rate or extent of frequency, rate or extent of zygospore formation, a process in which a thick-walled spore of some algae and fungi is formed by union of two similar sexual cells, usually serves as a resting spore, and produces the sporophytic phase.


name: positive regulation of sexual sporulation resulting in formation of a cellular spore

description: Any process that activates, maintains or increases the frequency, rate or extent of the formation of cellular spores derived from the products of meiosis.


name: positive regulation of ascospore formation

description: Any process that activates, maintains or increases the frequency, rate or extent of ascospore formation, a process in which a sexual spore, named ascospore, from Ascomycete fungi was produced inside an ascus.


name: positive regulation of oospore formation

description: Any process that activates, maintains or increases the frequency, rate or extent of oospore formation, a process in which male and female gametangia develop and fuse to form a thick-walled resting spore of oomycetes.


chromosomal region

category: biolink:CellularComponent biolink:AnatomicalEntity biolink:PhysicalEssence biolink:OrganismalEntity biolink:SubjectOfInvestigation biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: Any subdivision of a chromosome along its length.


name: condensed chromosome, centromeric region

description: The region of a condensed chromosome that includes the centromere and associated proteins, including the kinetochore. In monocentric chromosomes, this region corresponds to a single area of the chromosome, whereas in holocentric chromosomes, it is evenly distributed along the chromosome.


name: aldonate transmembrane transporter activity

category: biolink:MolecularActivity biolink:Occurrent biolink:OntologyClass biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: Enables the transfer of aldonate from one side of a membrane to the other.


regulation of keratinocyte migration

description: Any process that modulates the frequency, rate or extent of keratinocyte migration.


N-acylethanolamine metabolic process

description: The chemical reactions and pathways involving N-acylethanolamines. An N-acylethanolamine is an ethanolamine substituted at nitrogen by an acyl group.


name: negative regulation of leukocyte apoptotic process

description: Any process that stops, prevents, or reduces the frequency, rate or extent of leukocyte apoptotic process.


NADH pyrophosphatase activity

description: Catalysis of the reaction: NADH + H2O = AMP + NMNH + 2 H+.


name: negative regulation of wound healing, spreading of epidermal cells

description: Any process that stops, prevents or reduces the frequency, rate or extent of wound healing, spreading of epidermal cells.


name: maturation of SSU-rRNA from tetracistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 4.5S-rRNA, 5S-rRNA)

description: Any process involved in the maturation of a precursor Small SubUnit (SSU) ribosomal RNA (rRNA) molecule into a mature SSU-rRNA molecule from the pre-rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 4.5S rRNA, and the 5S rRNA in that order from 5' to 3' along the primary transcript.


description: Catalysis of the reaction: 4-hydroxybenzoate + UDP-D-glucose = 4-(beta-D-glucosyloxy)benzoate + H+ + UDP.


description: Catalysis of the reaction: dolichol-phosphate + UDP-D-xylose = dolichyl D-xylosyl phosphate + UDP.


interleukin-35 receptor activity

description: Combining with interleukin-35 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


name: negative regulation of G1 to G0 transition

description: Any process that stops, prevents or reduces the frequency, rate or extent of G1 to G0 transition.


name: unsaturated monocarboxylic acid metabolic process

description: The chemical reactions and pathways involving unsaturated monocarboxylic acids, any organic acid containing one carboxyl (COOH) group or anion (COO-) and one or more unsaturated C-C bonds.


cellular hypotonic response

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a hypotonic environment, i.e. an environment with a lower concentration of solutes than the organism or cell.


description: Catalysis of the reaction: S-adenosyl-L-methionine + adenine in mRNA = S-adenosyl-L-homocysteine + N(1)-methyladenine in mRNA.


carboxylic acid catabolic process

description: The chemical reactions and pathways resulting in the breakdown of carboxylic acids, any organic acid containing one or more carboxyl (-COOH) groups.


name: negative regulation of necroptotic process

description: Any process that decreases the rate, frequency or extent of a necroptotic process, a necrotic cell death process that results from the activation of endogenous cellular processes, such as signaling involving death domain receptors or Toll-like receptors.


name: histone H3K18 acetyltransferase activity

description: Catalysis of the reaction: acetyl-CoA + histone H3 L-lysine (position 18) = CoA + histone H3 N6-acetyl-L-lysine (position 18).


name: beta-alanine catabolic process to mevalonate semialdehyde, by transamination

description: The chemical reactions and pathways resulting in the breakdown of beta-alanine into other compounds, including mevalonate semialdehyde, by transamination.


sterigmatocystin biosynthetic process

description: The chemical reactions and pathways resulting in the formation of sterigmatocystin, a carcinogenic mycotoxin produced in high yields by strains of the common molds.


name: negative regulation of small molecule metabolic process

description: Any process that stops, prevents or reduces the frequency, rate or extent of a small molecule metabolic process.


mRNA 5'-UTR binding

description: Binding to an mRNA molecule at its 5' untranslated region.


geraniol metabolic process

description: The chemical reactions and pathways involving geraniol.


arginine deiminase pathway

description: The chemical reactions and pathways resulting in the breakdown of arginine into other compounds, including ornithine and CO2, using the enzyme arginine deiminase.


endodermal-mesodermal cell signaling

description: Any process that mediates the transfer of information from endodermal cells to mesodermal cells.


name: envenomation resulting in negative regulation of blood coagulation in another organism

description: A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant stopping, prevention or reduction in the frequency, rate or extent of blood coagulation in the bitten organism.


DNA integration

description: The process in which a DNA segment is incorporated into another, usually larger, DNA molecule such as a chromosome.


immune effector process

description: Any process of the immune system that executes a component of an immune response. An effector immune process takes place after its activation.


name: regulation of D-xylose catabolic process

description: Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of xylose.


name: negative regulation of keratinocyte differentiation

description: Any process that stops, prevents, or reduces the frequency, rate or extent of keratinocyte differentiation.


histone H4K12 deacetylase activity

description: Catalysis of the reaction: histone H4 N6-acetyl-L-lysine (position 12) + H2O = histone H4 L-lysine (position 12) + acetate. This reaction represents the removal of an acetyl group from lysine at position 12 of the histone H4 protein.


cellular response to amyloid-beta

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a amyloid-beta stimulus.


establishment of localization

description: Any process that localizes a substance or cellular component. This may occur via movement, tethering or selective degradation.


mannitol catabolic process

description: The chemical reactions and pathways resulting in the breakdown of mannitol, the alditol derived from D-mannose by reduction of the aldehyde group.


rRNA (guanine-N7)-methylation

description: The addition of a methyl group to the N7 atom in the base portion of a guanine nucleotide residue in an rRNA molecule.


glucose catabolic process to pyruvate

description: The chemical reactions and pathways resulting in the breakdown of glucose, with the production of pyruvate.


name: negative regulation of flavonol biosynthetic process

description: Any process that stops, prevents or reduces the frequency, rate or extent of flavonol biosynthetic process.


synapse assembly

description: The aggregation, arrangement and bonding together of a set of components to form a synapse. This process ends when the synapse is mature (functional).


cellular response to fatty acid

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fatty acid stimulus.


name: macrophage migration inhibitory factor signaling pathway

category: biolink:Pathway biolink:OntologyClass biolink:BiologicalProcess biolink:Occurrent biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: The series of molecular signals initiated by macrophage migration inhibitory factor binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.


name: symbiont-mediated suppression of host antigen processing and presentation of peptide antigen via MHC class I

description: A process by which a symbiont inhibits or disrupts the normal processing and presentation of a peptide antigen on its cell surface in association with an MHC class I transmembrane protein complex. One mechanism of suppression is by direct inhibition of host tapasin, a type I transmembrane protein essential for the optimal expression of stable MHC class I molecules on the host cell surface. By inhibiting host tapasin activity, some viruses can prevent presentation of their antigens at the cell surface, and thereby evade the host anti-viral immune response.


cellular component disassembly

description: A cellular process that results in the breakdown of a cellular component.


name: histone H3R17 methyltransferase activity

description: Catalysis of the reaction: S-adenosyl-L-methionine + (histone H3)-arginine (position 17) = S-adenosyl-L-homocysteine + (histone H3)-N-methyl-arginine (position 17). This reaction is the addition of a methyl group to the arginine residue at position 17 of histone H3.


name: negative regulation of IRE1-mediated unfolded protein response

description: Any process that stops, prevents or reduces the frequency, rate or extent of the IRE1-mediated unfolded protein response.


name: regulation of blood vessel endothelial cell migration

description: Any process that modulates the frequency, rate or extent of the migration of the endothelial cells of blood vessels.


name: modulation by symbiont of defense-related host calcium-dependent protein kinase pathway

description: Any process in which an organism modulates the frequency, rate or extent of the host calcium-dependent protein kinase signal transduction pathways during the host defense response. The host is defined as the larger of the organisms involved in a symbiotic interaction.


name: apoptotic process in response to mitochondrial fragmentation

description: Any apoptotic process that occurs as a result of mitochondrial fragmentation.


modulation of host virulence by virus

description: A process by which a virus improves the virulence of its host for that host's respective host. Common in but not limited to bacteriophages; also occurs in phage-bearing bacteria infecting plants or animals for example. Mechanisms include the expression of factors that modulate a bacterial adhesion to a host cell, spread through host tissues, production of exotoxins or provide protection against host immune defenses.


regulation of DNA recombination

description: Any process that modulates the frequency, rate or extent of DNA recombination, a DNA metabolic process in which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents.


coenzyme M biosynthetic process

description: The chemical reactions and pathways resulting in the formation of coenzyme M (2-thioethansulfonate), a coenzyme involved in the utilization of methane by methanogenic prokaryotes.


5S rRNA primary transcript binding

description: Binding to an unprocessed 5S ribosomal RNA transcript.


pre-mRNA 5'-splice site binding

description: Binding to a pre-mRNA 5' splice site sequence.


biogenic amine metabolic process

description: The chemical reactions and pathways occurring at the level of individual cells involving any of a group of naturally occurring, biologically active amines, such as norepinephrine, histamine, and serotonin, many of which act as neurotransmitters.


name: metal ion transmembrane transporter activity

description: Enables the transfer of metal ions from one side of a membrane to the other.


cytokinin receptor activity

description: Combining with a cytokinin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


GAA codon-amino acid adaptor activity

description: A triplet codon-amino acid adaptor activity that recognizes a GAA codon.


vitamin D receptor signaling pathway

description: A nuclear receptor-mediated signaling pathway initiated by vitamin D binding to an intracellular receptor of the nuclear receptor protein family, and ending with regulation of a downstream cellular process, e.g. transcription.


name: negative regulation of toll-like receptor 7 signaling pathway

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 7 signaling pathway.


name: positive regulation of glutathione biosynthetic process

description: Any process that activates or increases the frequency, rate or extent of glutathione biosynthetic process.


description: Catalysis of the reaction: adenosine(58) in tRNA + S-adenosyl-L-methionine = H+ + N(1)-methyladenosine(58) in tRNA + S-adenosyl-L-homocysteine.


photorespiration

description: A light-dependent catabolic process occurring concomitantly with photosynthesis in plants (especially C3 plants) whereby dioxygen (O2) is consumed and carbon dioxide (CO2) is evolved. The substrate is glycolate formed in large quantities in chloroplasts from 2-phosphoglycolate generated from ribulose 1,5-bisphosphate by the action of ribulose-bisphosphate carboxylase; the glycolate enters the peroxisomes where it is converted by glycolate oxidase to glyoxylate which undergoes transamination to glycine. This then passes into the mitochondria where it is decarboxylated forming one molecule of serine for every two molecules of glycine. This pathway also exists in photosynthetic bacteria.


funalenone biosynthetic process

description: The chemical reactions and pathways resulting in the formation of funalenone.


N-glycan processing

description: The conversion of N-linked glycan (N = nitrogen) structures from the initially transferred oligosaccharide to a mature form, by the actions of glycosidases and glycosyltransferases. The early processing steps are conserved and play roles in glycoprotein folding and trafficking.


name: negative regulation of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity

description: Any process that decreases the frequency or rate of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity.


name: G protein-coupled purinergic receptor signaling pathway

description: A G protein-coupled receptor signaling pathway initiated by an extracellular purine or purine derivative binding to its receptor, and ending with the regulation of a downstream cellular process.


cell recognition

description: The process in which a cell in an organism interprets its surroundings.


tachykinin receptor signaling pathway

description: A G protein-coupled receptor signaling pathway initiated by tachykinin binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process. Tachykinin is a short peptide with the terminal sequence (Phe-X-Gly-Leu-Met-NH2).


name: cellular response to organic cyclic compound

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus.


name: complement component C3a receptor activity

description: Combining with the C3a product of the complement cascade and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


description: Catalysis of the reaction: UDP-glucose + 5,7,3',4'-tetrahydroxyflavone = UDP + 7-O-beta-D-glucosyl-5,7,3',4'-tetrahydroxyflavone.


Lands organization

description: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of Lands, a class of nuclear body that react against SP140 auto-antibodies.


epithelial tube formation

description: The developmental process pertaining to the initial formation of an epithelial tube.


description: The chemical reactions and pathways involving N-acylphosphatidylethanolamines. An N-acylphosphatidylethanolamine is a phosphatidylethanolamine substituted at nitrogen by an acyl group.


menstrual cycle

description: A type of ovulation cycle where the endometrium is shed if pregnancy does not occur.


tricarboxylic acid metabolic process

description: The chemical reactions and pathways involving dicarboxylic acids, any organic acid containing three carboxyl (COOH) groups or anions (COO-).


name: envenomation resulting in muscle damage in another organism

description: A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with resultant muscle damage in the bitten organism.


viral capsid assembly

description: The assembly of a virus capsid from its protein subunits.


regulation of fat cell differentiation

description: Any process that modulates the frequency, rate or extent of adipocyte differentiation.


name: glutamate catabolic process to 4-hydroxybutyrate

description: The chemical reactions and pathways resulting in the breakdown of glutamate into 4-hydroxybutyrate.


name: regulation of galactomannan catabolic process

description: Any process that modulates the frequency, rate or extent of galactomannan catabolic process.


name: envenomation resulting in fibrinogenolysis in another organism

description: The process which begins with venom being forced into an organism by the bite or sting of another organism, and ends with fibrinogenolysis, a process that degrades fibrinogen at a variety of Arg-Lys bonds, thus impairing fibrinogen clotting in the bloodstream of the bitten/stung organism.


name: DNA strand elongation involved in premeiotic DNA replication

description: Any DNA strand elongation involved in meiotic cell cycle DNA replication.


description: Catalysis of the reaction: alpha-aminoadipate + acetyl-CoA = N2-acetyl-alpha-aminoadipate + coenzyme A.


name: symbiont-mediated perturbation of host defenses

description: A process in which a symbiont alters or subverts the normal execution of a host organism's defense response. The host defense response is mounted by the host in response to the presence of the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction.


name: retrograde trans-synaptic signaling by neuropeptide

description: Cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by a neuropeptide.


name: choline biosynthetic process via N-monomethylethanolamine

description: The chemical reactions and pathways resulting in the formation of choline (2-hydroxyethyltrimethylammonium), via the intermediate N-monomethylethanolamine.


name: proton motive force-driven plasma membrane ATP synthesis

description: The transport of protons across the plasma membrane to generate an electrochemical gradient (proton-motive force) that powers ATP synthesis.


mitotic cell cycle, embryonic

description: The eukaryotic cell cycle in which a cell is duplicated without changing ploidy, occurring in the embryo.


name: envenomation resulting in positive regulation of platelet aggregation in another organism

description: A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant activation, maintenance or an increase in the frequency, rate or extent of platelet aggregation in the bitten organism.


name: positive regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process

description: Any process that activates or increases the frequency, rate or extent of an adenylate cyclase-activating adrenergic receptor signaling pathway involved in some heart process.


isopeptide cross-linking

description: The formation of a covalent cross-link between or within peptide chains, where either the amino group or the carboxyl group, or both, are not attached to the alpha carbon.


name: iron and molybdenum incorporation into iron-molybdenum-sulfur cluster via L-cysteinyl homocitryl molybdenum-heptairon-nonasulfide

description: The incorporation of iron and molybdenum into a Mo-7Fe-8S iron-molybdenum-sulfur cluster via L-cysteinyl homocitryl molybdenum-heptairon-nonasulfide, found in nitrogenase.


ethylene-activated signaling pathway

description: The series of molecular signals generated by the reception of ethylene (ethene, C2H4) by a receptor and ending with modulation of a cellular process, e.g. transcription.


gliotoxin catabolic process

description: The chemical reactions and pathways resulting in the breakdown of the epipolythiodioxopiperazine gliotoxin, a poisonous substance produced by some species of fungi.


name: alpha-linked polysaccharide catabolism to maltopentaose

description: The breakdown of large alpha-linked polysaccharides by hydrolysis of (1->4)-alpha-D-glucosidic linkages to yield maltopentaose.


protein catabolic process at presynapse

description: The chemical reactions and pathways resulting in the breakdown of a protein at a presynapse.


mannoprotein biosynthetic process

description: The chemical reactions and pathways resulting in the formation of a mannoprotein, a protein that contains covalently bound mannose residues.


pentitol biosynthetic process

description: The chemical reactions and pathways resulting in the formation of pentitols, any alditol with a chain of five carbon atoms in the molecule.


collagen receptor activity

description: Combining with a collagen and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


cyclohexanol metabolic process

description: The chemical reactions and pathways involving cyclohexanol, the monohydroxy derivative of cyclohexane. It is used as a solvent and blending agent.


prenylcysteine metabolic process

description: The chemical reactions and pathways involving prenylcysteine, 3-methyl-2-buten-1-yl-cysteine, a derivative of the amino acid cysteine formed by the covalent addition of a prenyl residue.


palmitic acid catabolic process

description: The chemical reactions and pathways resulting in the breakdown of palmitic acid.


name: endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

description: Endonucleolytic cleavage between the SSU-rRNA and the 5.8S rRNA of an rRNA molecule originally produced as a tricistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript.


description: Catalysis of the reaction: p-hydroxybenzoate + solanesyl pyrophosphate = nonaprenyl-4-hydroxybenzoate + diphosphate.


name: transforming growth factor beta receptor superfamily signaling pathway

description: The series of molecular signals initiated by an extracellular ligand binding to a member of the transforming growth factor receptor superfamily, and ending with the regulation of a downstream cellular process, e.g. transcription.


name: cell surface receptor protein serine/threonine kinase signaling pathway

description: The series of molecular signals initiated by an extracellular ligand binding to a receptor on the surface of the target cell where the receptor possesses serine/threonine kinase activity, and ending with the regulation of a downstream cellular process, e.g. transcription.


description: The chemical reactions and pathways involving sophorosyloxydocosanoate, 13-sophorosyloxydocosanoate 6',6''-diacetate, an aromatic hydrocarbon.


name: peptidyl-L-glutamyl 5-omega-hydroxyceramide ester biosynthetic process from peptidyl-glutamine

description: The modification of peptidyl-glutamine residues by deamidation and esterification with omega-hydroxyceramide.


name: basement membrane assembly involved in embryonic body morphogenesis

description: Any basement membrane assembly that is involved in embryonic body morphogenesis.


name: positive regulation of opioid receptor signaling pathway

description: Any process that activates or increases the frequency, rate or extent of opioid receptor signaling pathway.


NADH regeneration

description: A metabolic process that generates a pool of NADH by the reduction of NAD+.


name: guanylate kinase-associated protein clustering

description: The clustering process in which guanylate kinase-associated proteins (GKAPs) are localized to distinct domains in the cell membrane. GKAP facilitates assembly of the post synaptic density of neurons.


name: positive regulation of heme biosynthetic process

description: Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of heme.


name: folic acid transmembrane transporter activity

description: Enables the transfer of folic acid (pteroylglutamic acid) from one side of a membrane to the other. Folic acid is widely distributed as a member of the vitamin B complex and is essential for the synthesis of purine and pyrimidines.


autolysis

description: A programmed cell death process observed in bacteria and filamentous fungi and leading to spontaneous death by lysis. Examples are lysis of the mother cell during sporulation of Bacillus subtilis and self-degradation of fungal cells in Aspergillus nidulans. Autolysis is also involved in bacterial biofilm formation.


name: N-terminal peptidyl-proline dimethylation involved in translation

description: An N-terminal peptidyl-proline dimethylation process that contributes to translation.


name: protein localization to microtubule minus-end

description: A process in which a protein is transported to, or maintained in, a location at a microtubule minus-end.


name: positive regulation of macrophage colony-stimulating factor signaling pathway

description: Any process that activates or increases the frequency, rate or extent of macrophage colony-stimulating factor signaling pathway.


spindle checkpoint signaling

description: A signaling process that that controls a cell cycle checkpoint that originates from the mitotic or meiotic spindle.


carbazole catabolic process

description: The chemical reactions and pathways resulting in the breakdown of carbazole, a heterocyclic aromatic compound containing a dibenzopyrrole system that is produced during coal gasification and is present in cigarette smoke. Coal tar produced at high temperature contains an average of 1.5% carbazole. It is used widely in synthesis of dyes, pharmaceuticals, and plastics and is a suspected carcinogen.


ICAM-3 receptor activity

description: Combining with ICAM-3, intercellular adhesion molecule 3, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. ICAM-3, or CD50, are constitutively expressed on monocytes, granulocytes and lymphocytes; on physiological stimulation, they become transiently phosphorylated on serine residues.


regulation of Kit signaling pathway

description: Any process that modulates the frequency, rate or extent of Kit signaling pathway.


1,2-dichloroethane catabolic process

description: The chemical reactions and pathways resulting in the breakdown of 1,2-dichloroethane, a major commodity chemical used, for example, in the manufacture of vinyl chloride.


name: negative regulation of Toll signaling pathway

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the Tl signaling pathway.


organomercury biosynthetic process

description: The chemical reactions and pathways resulting in the formation of organomercury compounds, any organic compound containing a mercury atom.


name: cyanidin 3-O-glucoside biosynthetic process

description: The chemical reactions and pathways resulting in the formation of cyanidin 3-O-glucoside, a basic anthocyanin responsible for red to magenta coloration of flowers and fruits.


serine-isocitrate lyase pathway

description: A one-carbon metabolic process in which acetyl-CoA is produced from formaldehyde and carbon dioxide.


blue light signaling pathway

description: The series of molecular signals initiated upon sensing of blue light by photoreceptor molecule, at a wavelength between 400nm and 470nm.


coenzyme A catabolic process

description: The chemical reactions and pathways resulting in the breakdown of coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester.


carbon-sulfur lyase activity

description: Catalysis of the elimination of hydrogen sulfide or substituted H2S.


cellular response to proline

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a proline stimulus.


name: maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, LSU-rRNA,5S)

description: Any process involved in the maturation of a precursor Large SubUnit (LSU) ribosomal RNA (rRNA) molecule into a mature LSU-rRNA molecule from the pre-rRNA molecule originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 5S rRNA in that order from 5' to 3' along the primary transcript.


suberin biosynthetic process

description: The chemical reactions and pathways resulting in the formation of suberin monomers and suberin polyesters. Suberin monomers are derived from fatty acids and trans-cinnamic acids. The monomers are then cross-linked with glycerols.


modulation by host of symbiont process

description: The process in which an host alters or subverts a process in a symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.


F-9775A metabolic process

description: The chemical reactions and pathways involving F-9775A.


isopentenol biosynthetic process

description: The chemical reactions and pathways resulting in the formation of isopentenol.


protein deglutamylation

description: The removal of a glutamate residue from a protein. Glutamate residues in proteins can be gene-encoded, or added as side chains during the protein modification process of polyglutamylation.


name: regulation of ornithine metabolic process

description: Any process that modulates the rate, frequency, or extent of the chemical reactions and pathways involving ornithine, an amino acid only rarely found in proteins, but which is important in living organisms as an intermediate in the reactions of the urea cycle and in arginine biosynthesis.


name: negative regulation of adenylate cyclase-inhibiting opioid receptor signaling pathway

description: Any process that stops, prevents or reduces the frequency, rate or extent of adenylate cyclase-inhibiting opioid receptor signaling pathway.


preblastoderm mitotic cell cycle

description: The first nine mitotic division cycles of the insect embryo, during which the dividing nuclei lie deep in the interior of the egg and divide nearly synchronously. This is the first phase of the syncytial period where nuclei divide in a common cytoplasm without cytokinesis.


xylulose catabolic process

description: The chemical reactions and pathways resulting in the breakdown of xylulose, the ketopentose threo-2-pentulose.


name: regulation of meiotic cell cycle process involved in oocyte maturation

description: Any process that modulates the frequency, rate or extent of meiotic cell cycle process involved in oocyte maturation.


name: epidermal growth factor receptor activity

description: Combining with an epidermal growth factor receptor ligand and transmitting the signal across the plasma membrane to initiate a change in cell activity.


brassinosteroid catabolic process

description: The chemical reactions and pathways resulting in the breakdown of brassinosteroids, any of a group of steroid derivatives that occur at very low concentrations in plant tissues and may have hormone-like effects.


xyloglucan biosynthetic process

description: The chemical reactions and pathways resulting in the formation of xyloglucan, the cross-linking glycan composed of (1->4)-beta-D glucan backbone substituted at regular intervals with beta-D-xylosyl-(1->6) residues, which is present in the primary cell wall of most higher plants.


lincomycin biosynthetic process

description: The chemical reactions and pathways resulting in the formation of lincomycin.


name: microtubule-dependent intracellular transport of viral material towards nucleus

description: The directed movement of a virus, or part of a virus, towards the host cell nucleus using host microtubules.


description: The chemical reactions and pathways resulting in the formation of 4-amino-3-isothiazolinone, five-membered saturated heterocyclic ring structures containing a sulfur and a nitrogen in the 1-position and 2-positions respectively.


gamete generation

description: The generation and maintenance of gametes in a multicellular organism. A gamete is a haploid reproductive cell.


name: tetrapyrrole biosynthetic process from glycine and succinyl-CoA

description: The chemical reactions and pathways leading to the formation of tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next, from other compounds, including glycine and succinyl-CoA.


cap snatching

description: A transcription initiation process during which a nucleotide sequence between 10 and 20 nucleotides in size is cleaved from the 5' end of host mRNAs by a viral RNA-dependent polymerase. The capped leader sequence obtained is subsequently used to prime transcription on the viral genome, which ultimately leads to the synthesis of capped, translatable viral mRNAs.


extrasynaptic signaling via GABA

description: Cell-cell signaling that starts with the activation of extrasynaptic GABA receptors in neurons through binding of ambient gamma-aminobutyric acid present in the extracellular fluid.


name: negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process

description: Any process that stops, prevents or reduces the frequency, rate or extent of an adenylate cyclase-activating adrenergic receptor signaling pathway involved in some heart process.


name: negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell

description: Any process that stops, prevents or reduces the frequency, rate or extent of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell.


name: low-density lipoprotein particle mediated signaling

description: The series of molecular signals mediated by the detection of low-density lipoprotein particle.


name: cellular response to tumor necrosis factor

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tumor necrosis factor stimulus.


imidazole N-acetyltransferase activity

description: Catalysis of the reaction: 1H-imidazole + acetyl-CoA = N-acetylimidazole + CoA.


name: cell-cell signaling involved in cell fate commitment

description: Signaling at long or short range between cells that results in the commitment of a cell to a certain fate.


galactitol catabolic process

description: The chemical reactions and pathways resulting in the breakdown of galactitol, the hexitol derived by the reduction of the aldehyde group of either D- or L-galactose.


name: regulation of cell migration involved in somitogenic axis elongation

description: Any process that modulates the frequency, rate, or extent of the controlled self-propelled movement of a cell that contributes to somitogenic axis elongation.