name: cellular response to leukemia inhibitory factor

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leukemia inhibitory factor stimulus.


name: uridine-rich cytoplasmic polyadenylylation element binding

category: biolink:MolecularActivity biolink:Occurrent biolink:OntologyClass biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: Binding to a U-rich sequence in the 3'-end of nuclear-transcribed mRNAs; required for cytoplasmic polyadenylylation.


UV-damage excision repair

category: biolink:BiologicalProcess biolink:Occurrent biolink:OntologyClass biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: A DNA repair process that is initiated by an endonuclease that introduces a single-strand incision immediately 5' of a UV-induced damage site. UV-damage excision repair acts on both cyclobutane pyrimidine dimers (CPDs) and pyrimidine-pyrimidone 6-4 photoproducts (6-4PPs).


1,4-dichlorobenzene catabolic process

description: The chemical reactions and pathways resulting in the breakdown of 1,4-dichlorobenzene (p-dichlorobenzene or paramoth), a derivative of benzene with two chlorine atoms attached at opposite positions on the ring.


name: protein localization to lateral cortical node

description: A process in which a protein is transported to, or maintained in, a location within a lateral cortical node.


mitochondrial DNA metabolic process

description: The chemical reactions and pathways involving mitochondrial DNA.


protein uridylylation

description: The addition of phospho-uridine to a protein amino acid.


description: The chemical reactions and pathways resulting in the formation of trimethylenediamine.


ADP catabolic process

description: The chemical reactions and pathways resulting in the breakdown of ADP, adenosine 5'-diphosphate.


name: aspartate family amino acid catabolic process

description: The chemical reactions and pathways resulting in the breakdown of amino acids of the aspartate family, comprising asparagine, aspartate, lysine, methionine and threonine.


name: RNA-protein covalent cross-linking via peptidyl-serine

description: The formation of a covalent cross-link between RNA and a peptidyl-serine residue by the formation of O-(phospho-5'-5NA)-L-serine.


name: protein insertion into membrane from inner side

description: The process in which a protein is incorporated into a lipid bilayer, e.g., the prokaryotic, mitochondrial, or chloroplast inner membrane, from the inner side.


cellular response to glucose starvation

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of glucose.


name: adenylate cyclase-inhibiting dopamine receptor signaling pathway

category: biolink:Pathway biolink:OntologyClass biolink:BiologicalProcess biolink:Occurrent biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: An adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway initiated by dopamine binding to its receptor, and ending with the regulation of a downstream cellular process.


sno(s)RNA 3'-end cleavage

description: The endonucleolytic cleavage of snoRNA 3' ends, which is required for mature snoRNAs to be functional.


name: positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response

description: Any process that activates or increases the frequency, rate or extent of differentiation of CD4-positive, CD25-positive, alpha-beta regulatory T cells as part of an immune response.


name: negative regulation of plant-type hypersensitive response

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the hypersensitive response in a plant.


name: phenol-containing compound catabolic process

description: The chemical reactions and pathways resulting in the breakdown of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring.


dense core granule maturation

description: Steps required to transform a dense core granule generated at the trans-Golgi network into a fully formed and transmissible dense core granule. Dense core granule maturation proceeds through clathrin-mediated membrane remodeling events and is essential for efficient processing of cargo within dense core granules as well as for removing factors that might otherwise interfere with dense core granule trafficking and exocytosis.


name: branched-chain amino acid:sodium symporter activity

description: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: branched-chain amino acid(out) + cation(out) = branched-chain amino acid(in) + cation(in).


name: L-cysteine catabolic process via cystine

description: The chemical reactions and pathways resulting in the breakdown of L-cysteine, via the intermediate cystine.


ethanol biosynthetic process

description: The chemical reactions and pathways resulting in the formation of ethanol, CH3-CH2-OH, a colorless, water-miscible, flammable liquid produced by alcoholic fermentation.


serotonin receptor activity

description: Combining with the biogenic amine serotonin and transmitting a signal across a membrane by activating some effector activity. Serotonin (5-hydroxytryptamine) is a neurotransmitter and hormone found in vertebrates and invertebrates.


name: receptor-mediated virion attachment to host cell

description: The process by which a virion attaches to a host cell by binding to a receptor on the host cell surface.


name: symbiont-mediated suppression of host translation termination

description: A process in which a symbiont inhibits or disrupts translation termination of host mRNAs. The host is defined as the larger of the organisms involved in a symbiotic interaction.


cordyol C catabolic process

description: The chemical reactions and pathways resulting in the breakdown of cordyol C.


complement receptor activity

description: Combining with any component or product of the complement cascade and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


name: positive regulation of pattern recognition receptor signaling pathway

description: Any process that decreases the rate, frequency or extent of a pattern recognition receptor signaling pathway.


name: intracellularly calcium-gated chloride channel activity

description: Enables the transmembrane transfer of chloride by a channel that opens in response to stimulus by a calcium ion or ions. Transport by a channel involves catalysis of facilitated diffusion of a solute (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel, without evidence for a carrier-mediated mechanism.


ubiquinone-6 biosynthetic process

description: The chemical reactions and pathways resulting in the formation of ubiquinone-6.


name: response to G2 DNA damage checkpoint signaling

description: A process that occurs in response to signals generated as a result of G2/M transition DNA damage checkpoint signaling.


name: cortical actin cytoskeleton organization

description: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of actin-based cytoskeletal structures in the cell cortex, i.e. just beneath the plasma membrane.


name: regulation of endothelial cell chemotaxis to vascular endothelial growth factor

description: Any process that modulates the frequency, rate or extent of endothelial cell chemotaxis to vascular endothelial growth factor.


name: negative regulation of mitotic cell cycle phase transition

description: Any process that stops, prevents or reduces the frequency, rate or extent of mitotic cell cycle phase transition.


adenine biosynthetic process

description: The chemical reactions and pathways resulting in the formation of adenine, 6-aminopurine, one of the five main bases found in nucleic acids and a component of numerous important derivatives of its corresponding ribonucleoside, adenosine.


type IIa hypersensitivity

description: An inflammatory response resulting in cell death mediated by activation of the classical complement pathway or induction of effector cell phagocytosis or cytolysis mechanisms via complement or Fc receptors following the binding of antibodies to cell surface antigens on a target cell.


cellular response to caffeine

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a caffeine stimulus. Caffeine is an alkaloid found in numerous plant species, where it acts as a natural pesticide that paralyzes and kills certain insects feeding upon them.


apocarotenoid catabolic process

description: The chemical reactions and pathways resulting in the breakdown of apocarotenoids, a class of compounds derived from the oxidative cleavage of carotenoids, many of which are biologically important e.g. retinal and abscisic acid.


pyrimidine nucleoside metabolic process

description: The chemical reactions and pathways involving any pyrimidine nucleoside, one of a family of organic molecules consisting of a pyrimidine base covalently bonded to ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside).


name: extracellular regulation of signal transduction

description: Any regulation of signal transduction that takes place in the extracellular region.


name: amino acid activation for nonribosomal peptide biosynthetic process

description: Activation of an amino acid for incorporation into a peptide by a nonribosomal process.


name: regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide

description: Any process that modulates the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to hydrogen peroxide.


carboxy-lyase activity

description: Catalysis of the nonhydrolytic addition or removal of a carboxyl group to or from a compound.


ectoine catabolic process

description: The chemical reactions and pathways resulting in the breakdown of ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidinecarboxylic acid), a tetrahydropyrimidine commonly synthesized by halophilic bacteria.


name: positive regulation of mesenchymal cell apoptotic process

description: Any process that activates or increases the frequency, rate or extent of mesenchymal cell apoptotic process.


name: regulation of respiratory burst involved in inflammatory response

description: Any process that modulates the rate, frequency or extent of a phase of elevated metabolic activity, during which oxygen consumption increases made as a defense response ; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals.


name: fibroblast growth factor receptor signaling pathway involved in heart development

description: The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands and contributing to the progression of the heart over time.


thiamine metabolic process

description: The chemical reactions and pathways involving thiamine (vitamin B1), a water soluble vitamin present in fresh vegetables and meats, especially liver.


name: clustering of voltage-gated sodium channels

description: The process in which voltage-gated sodium channels become localized together in high densities. In animals, nodes of Ranvier differ dramatically from internodal axonal regions in very high densities of voltage-dependent sodium (Nav) channels responsible for the rapid, inward ionic currents that produce membrane depolarization.


name: positive regulation of plant-type cell wall cellulose catabolic process

description: Any process that activates or increases the frequency, rate or extent of plant-type cell wall cellulose catabolic process.


oligodendrocyte apoptotic process

description: Any apoptotic process in an oligodendrocyte. Oligodendrocytes belong to a class of large neuroglial (macroglial) cells in the central nervous system, where they form the insulating myelin sheath of axons.


granzyme A production

description: The appearance of granzyme A due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


cellular response to hydroxyisoflavone

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydroxyisoflavone stimulus.


prostaglandin metabolic process

description: The chemical reactions and pathways involving prostaglandins, any of a group of biologically active metabolites which contain a cyclopentane ring due to the formation of a bond between two carbons of a fatty acid. They have a wide range of biological activities.


collagen metabolic process

description: The chemical reactions and pathways involving collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%).


name: peptidyl-lactic acid biosynthetic process from peptidyl-serine

description: The modification of N-terminal peptidyl-serine to lactic acid.


name: negative regulation of substrate-dependent cell migration, cell attachment to substrate

description: Any process that stops, prevents or reduces the frequency, rate or extent of substrate-dependent cell migration, cell attachment to substrate.


name: methyl tert-butyl ether metabolic process

description: The chemical reactions and pathways involving methyl tert-butyl ether, 2-methoxy-2-methylpropane. Methyl tert-butyl ether is a synthetic chemical which is mixed with gasoline for use in reformulated gasoline. It was first introduced as an additive for unleaded gasoline in the 1980s. It is also used as a laboratory reagent and a pharmaceutical agent.


name: protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity

description: Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + fructose(out) = protein histidine + fructose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.


metanephric short nephron development

description: The process whose specific outcome is the progression of a short nephron in the metanephros over time, from its formation to the mature structure. Short nephrons are associated with mid-cortical and superficial glomeruli, are situated entirely in the outer medulla, and have no thin ascending limb.


name: pituitary adenylate cyclase-activating polypeptide receptor activity

description: A G protein-coupled receptor that interacts with pituitary adenylate cyclase-activating polypeptide.


name: negative regulation of chlorophyll biosynthetic process

description: Any process that stops, prevents or reduces the frequency, rate or extent of chlorophyll biosynthetic process.


catecholamine metabolic process

description: The chemical reactions and pathways involving any of a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine.


name: cellular process involved in reproduction in multicellular organism

description: A process, occurring at the cellular level, that is involved in the reproductive function of a multicellular organism.


name: positive regulation of interleukin-17-mediated signaling pathway

description: Any process that activates or increases the frequency, rate or extent of interleukin-17-mediated signaling pathway.


IMP biosynthetic process

description: The chemical reactions and pathways resulting in the formation of IMP, inosine monophosphate.


name: retrograde trans-synaptic signaling by neuropeptide, modulating synaptic transmission

description: Modulation of synaptic transmission by cell-cell signaling across the synaptic cleft from postsynapse to presynapse, mediated by a neuropeptide.


cellular response to hydrogen sulfide

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen sulfide stimulus.


intronic box H/ACA snoRNA processing

description: Any process involved in the conversion of a primary box H/ACA type small nucleolar RNA (snoRNA) transcript that resides within, and is processed from, the intron of a pre-mRNA into a mature box H/ACA snoRNA.


ADP-ribose diphosphatase activity

description: Catalysis of the reaction: ADP-ribose + H2O = AMP + D-ribose 5-phosphate.


name: regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway

description: Any process that modulates the frequency, rate or extent of an endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway.


cellular response to decane

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a decane stimulus.


maintenance of seed dormancy

description: Any process that maintains a seed in a dormant state.


histone crotonyltransferase activity

description: Catalysis of the reaction: crotonyl-CoA + histone = CoA + crotonyl-histone.


name: positive regulation of complement-dependent cytotoxicity

description: Any process that activates or increases the frequency, rate or extent of complement-dependent cytotoxicity.


chlorophyll synthetase activity

description: Catalysis of the reaction: chlorophyllide a + 2 H+ + phytyl diphosphate = chlorophyll a + diphosphate.


name: L-idonate transmembrane transporter activity

description: Enables the transfer of L-idonate from one side of a membrane to the other. L-idonate is an aldonic acid derived from L-idose, an aldohexose which is epimeric with D-glucose.


cellular response to alcohol

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alcohol stimulus.


name: envenomation resulting in plasminogen activation in another organism

description: The process which begins with venom being forced into an organism by the bite or sting of another organism, and ends with the activation of plasminogen into plasmin in the bitten organism. This process includes cleavage at an internal Arg-Val site to form an N-terminal A-chain and C-terminal B-chain held together by a disulfide bond, and can include further proteolytic cleavage events to remove the preactivation peptide.


name: thiamine-containing compound catabolic process

description: The chemical reactions and pathways resulting in the breakdown of thiamine (vitamin B1), and compounds derived from it.


regulation of cell differentiation

description: Any process that modulates the frequency, rate or extent of cell differentiation, the process in which relatively unspecialized cells acquire specialized structural and functional features.


peptidyl-tryptophan hydroxylation

description: The hydroxylation of peptidyl-tryptophan, to form peptidyl-L-3-hydroxytryptophan.


cellular response to erythromycin

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an erythromycin stimulus.


nitrogen fixation

description: The process in which nitrogen is taken from its relatively inert molecular form (N2) in the atmosphere and converted into nitrogen compounds useful for other chemical processes, such as ammonia, nitrate and nitrogen dioxide.


description: Catalysis of the reaction: N-acetyl-LL-2,6-diaminopimelate + H2O = LL-2,6-diaminopimelate + acetate.


name: protein lipidation involved in autophagosome assembly

description: The protein lipidation process by which phosphatidylethanolamine is conjugated to a protein of the ATG8 family, leading to membrane insertion of the protein as a step in autophagosome assembly.


delta-carotene catabolic process

description: The chemical reactions and pathways resulting in the breakdown of delta-carotene.


septin ring assembly

description: The aggregation, arrangement and bonding together of septins and associated proteins to form an organized structure resembling a ring at the cell cortex.


name: sequestering of nodal from receptor via nodal binding

description: Binding to a nodal protein in the extracellular region, and inhibiting nodal signaling by preventing nodal from binding to its cell surface receptor.


viral gene expression

description: A process by which a viral gene is converted into a mature gene product or products (proteins or RNA). This includes viral transcription, processing to produce a mature RNA product, and viral translation.


regulation of ERBB signaling pathway

description: Any process that modulates the frequency, rate or extent of ERBB signaling pathway.


description: Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing 2'-O-methylguanosine.


name: negative regulation of raffinose biosynthetic process

description: Any process that stops, prevents or reduces the frequency, rate or extent of raffinose biosynthetic process.


name: positive regulation of lymphocyte activation

description: Any process that activates or increases the frequency, rate or extent of lymphocyte activation.


name: negative regulation of tumor necrosis factor-mediated signaling pathway

description: Any process that decreases the rate or extent of the tumor necrosis factor-mediated signaling pathway. The tumor necrosis factor-mediated signaling pathway is the series of molecular signals generated as a consequence of tumor necrosis factor binding to a cell surface receptor.


glucan metabolic process

description: The chemical reactions and pathways involving glucans, polysaccharides consisting only of glucose residues.


peptidyl-threonine modification

description: The modification of peptidyl-threonine.


seed dormancy process

description: A dormancy process in which dormancy (sometimes called a dormant state) is induced, maintained or broken in a seed. Seed dormancy is a suspension of most physiological activity and growth in a seed, including the embryo contained therein, that can be reactivated. It often requires special conditions for reactivation, such as specific temperature, scarification, or leaching of inhibitors.


sperm capacitation

description: A process required for sperm to reach fertilization competence. Sperm undergo an incompletely understood series of morphological and molecular maturational processes, termed capacitation, involving, among other processes, protein tyrosine phosphorylation and increased intracellular calcium.


name: positive regulation of small GTPase mediated signal transduction

description: Any process that activates or increases the frequency, rate or extent of small GTPase mediated signal transduction.


name: DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator

description: A cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, resulting in the induction of the transcription of p21 (also known as WAF1, CIP1 and SDI1) or any equivalent protein, in response to the detection of DNA damage.


inulin catabolic process

description: The chemical reactions and pathways resulting in the breakdown of inulin.


name: protease localization to mast cell secretory granule

description: Any process in which a protease is transported to, or maintained in, a location within a secretory granule in a mast cell.


fructose catabolic process

description: The chemical reactions and pathways resulting in the breakdown of fructose, the ketohexose arabino-2-hexulose.


name: regulation of initiation of premeiotic DNA replication

description: Any process that modulates the frequency, rate or extent of initiation of premeiotic DNA replication.


name: positive regulation of cellobiose catabolic process

description: Any process that activates or increases the frequency, rate or extent of cellobiose catabolic process.


dolichol biosynthetic process

description: The chemical reactions and pathways resulting in the formation of dolichols, any 2,3-dihydropolyprenol derived from four or more linked isoprene units.


peptidyl-lysine carboxyethylation

description: The modification of peptidyl-lysine to form peptidyl-N6-1-carboxyethyl-L-lysine.


arugosin metabolic process

description: The chemical reactions and pathways involving arugosin.


L-leucine metabolic process

description: The chemical reactions and pathways involving L-leucine, 2-amino-4-methylpentanoic acid.


name: carbohydrate derivative metabolic process

description: The chemical reactions and pathways involving carbohydrate derivative.


name: negative regulation of toll-like receptor 4 signaling pathway

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 4 signaling pathway.


name: positive regulation of endothelial cell chemotaxis to fibroblast growth factor

description: Any process that activates or increases the frequency, rate or extent of endothelial cell chemotaxis to fibroblast growth factor.


name: anaerobic phenol-containing compound catabolic process

description: The chemical reactions and pathways resulting in the breakdown of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring, in the absence of oxygen.


disproportionation of elemental sulfur

description: The process in which sulfur compounds with an intermediate oxidation state serve as both electron donors and electron acceptors in an energy-generating redox process. The reaction takes place anaerobically, in light and in the absence of CO2.


histone H3R2 methyltransferase activity

description: Catalysis of the reaction: S-adenosyl-L-methionine + (histone H3)-arginine (position 2) = S-adenosyl-L-homocysteine + (histone H3)-N-methyl-arginine (position 2). This reaction is the addition of a methyl group to the arginine residue at position 2 of histone H3.


macrolide metabolic process

description: The chemical reactions and pathways involving macrolides, any of a large group of polyketide compounds that contain a large lactone ring with few or no double bonds and no nitrogen atoms, linked glycosidically to one or more sugar groups. The macrolides include the carbomycins, the erythromycins, oleandomycin, oligomycins, and the spiramycins, and act as antibiotics, mainly against Gram-positive bacteria.


description: Catalysis of the reaction: all-trans-nonaprenyl diphosphate + H+ + homogentisate = 2-methyl-6-all-trans-nonaprenylbenzene-1,4-diol + CO2 + diphosphate. 2-methyl-6-solanyl-1,4-benzoquinonone is also known as 2-methyl-6-solanesylplastoquinol and all-trans-nonaprenyl diphosphate as solanesyl diphosphate.


purine nucleobase salvage

description: Any process that generates purine nucleobases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, from derivatives of them without de novo synthesis.


name: aerobic respiration, using nitrite as electron donor

description: The oxidation of nitrite (NO2) to nitrate (NO3), using oxygen (O2) as the electron acceptor. Nitrite oxidation is the final step in nitrification, the oxidation of ammonia to nitrate, and nitrite oxidoreductase (NOR) is the key enzyme complex that catalyzes the conversion of nitrite to nitrate in nitrite oxidizing species.


cellular response to antibiotic

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antibiotic stimulus. An antibiotic is a chemical substance produced by a microorganism which has the capacity to inhibit the growth of or to kill other microorganisms.


discadenine biosynthetic process

description: The chemical reactions and pathways resulting in the formation of discadenine, (2S)-2-amino-4-{6-[(3-methylbut-2-en-1-yl)amino]-3H-purin-3-yl}butanoic acid.


name: regulation protein catabolic process at presynapse

description: Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein at the presynapse.


interleukin-33 receptor activity

description: Combining with interleukin-33 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


name: GDP-mannose biosynthetic process from mannose

description: The chemical reactions and pathways resulting in the formation of GDP-mannose from mannose.


regulation of mRNA metabolic process

description: Any process that modulates the frequency, rate or extent of mRNA metabolic process.


cellular response to interleukin-17

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-17 stimulus.


name: double-strand break repair via single-strand annealing, removal of nonhomologous ends

description: During DSBR via single-strand annealing, the removal of nonhomologous sequences at the broken 3' single-strand DNA end before DNA repair synthesis can occur.


sno(s)RNA catabolic process

description: The chemical reactions and pathways resulting in the breakdown of snoRNA, small nucleolar RNA, any of a class of small RNAs that are associated with the eukaryotic nucleus as components of small nucleolar ribonucleoproteins.


name: killing by virus of host cell by post-segregational killing

description: The process by which a virus causes the death of daughter cells which do not contain its genes after host cell division, by a mechanism of post-segregational killing (PSK). The extrachromosomal viral DNA consist of two genes; the product of the second is long lived and toxic, while the product of the first is short lived and antagonizes the lethal action of the toxin. Daughter cells that do not contain the viral extrachromosomal element are killed by the long lived toxin, while daughter cells that do contain the viral extrachromosomal element are protected by the action of the short lived antitoxin it encodes.


description: The chemical reactions and pathways resulting in the formation of the exopolysaccharide galactosaminogalactan. GAG is a heteropolysaccharide composed of alpha-1,4 linked galactose, N-acetyl galactosamine (GalNAc) and galactosamine (GalN).


regulation of membrane potential

description: Any process that modulates the establishment or extent of a membrane potential, the electric potential existing across any membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane.


UDP-rhamnose metabolic process

description: The chemical reactions and pathways involving UDP-L-rhamnose, a substance composed of rhamnose in glycosidic linkage with uridine diphosphate.


name: TRAIL death-inducing signaling complex assembly

description: The aggregation, arrangement and bonding together of a set of components to form a TRAIL death-inducing signaling complex.


name: symbiont-mediated evasion of host innate immune response

description: A process by which a symbiont avoids recognition by host's innate immune response by altering, concealing or destroying a conserved symbiont molecule recognized by the host. The host is defined as the larger of the organisms involved in a symbiotic interaction.


name: positive regulation of border follicle cell migration

description: Any process that activates or increases the frequency, rate or extent of border follicle cell migration.


name: negative regulation of steroid metabolic process

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving steroids.


name: positive regulation of aortic smooth muscle cell differentiation

description: Any process that activates or increases the frequency, rate or extent of aortic smooth muscle cell differentiation.


myeloid dendritic cell chemotaxis

description: The movement of a myeloid dendritic cell in response to an external stimulus.


flagellated sperm motility

description: The directed, self-propelled movement of a cilium (aka flagellum) that contributes to the movement of a flagellated sperm.


viral budding from nuclear membrane

description: A viral budding that starts with formation of a membrane curvature in the host nuclear membrane.


name: negative regulation of hormone metabolic process

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving any hormone.


low-affinity IgE receptor activity

description: Combining with low affinity with an immunoglobulin of the IgE isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


RNA strand-exchange activity

description: Facilitates the displacement of one strand of an RNA-RNA duplex and its replacement with a different strand of higher complementarity.


name: choline biosynthetic process via CDP-choline

description: The chemical reactions and pathways resulting in the formation of choline (2-hydroxyethyltrimethylammonium), via the intermediate CDP-choline.


creatinine catabolic process to formate

description: The chemical reactions and pathways resulting in the breakdown of creatinine into other compounds, including formate.


name: positive regulation of Schwann cell migration

description: Any process that activates or increases the frequency, rate or extent of Schwann cell migration.


5S rRNA binding

description: Binding to a 5S ribosomal RNA, the smallest RNA constituent of a ribosome.


name: flavin-containing compound metabolic process

description: The chemical reactions and pathways involving a flavin, any derivative of the dimethylisoalloxazine (7,8-dimethylbenzo[g]pteridine-2,4(3H,10H)-dione) skeleton, with a substituent on the 10 position.


name: shikimate transmembrane transporter activity

description: Enables the transfer of shikimate from one side of a membrane to the other. Shikimate is an important intermediate in the biosynthesis of aromatic amino acids.


halogen metabolic process

description: The chemical reactions and pathways involving any halogen, elements of Group VII; includes metabolism of halogen-containing compounds.


corrin metabolic process

description: The chemical reactions and pathways involving corrin, C19H22N4, the fundamental heterocyclic skeleton of the corrinoids. It consists of four reduced pyrrole rings joined into a macrocyclic ring. Corrin is the core of the vitamin B12 molecule.


peptidyl-threonine octanoylation

description: The octanoylation of peptidyl-threonine to form peptidyl-O3-octanoyl-L-threonine, typical of the protein ghrelin.


Fc-gamma receptor signaling pathway

description: The series of molecular signals initiated by the binding of the Fc portion of immunoglobulin G (IgG) to an Fc-gamma receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. The Fc portion of an immunoglobulin is its C-terminal constant region.


nucleobase metabolic process

description: The chemical reactions and pathways involving a nucleobase, a nitrogenous base that is a constituent of a nucleic acid, e.g. the purines: adenine, guanine, hypoxanthine, xanthine and the pyrimidines: cytosine, uracil, thymine.


name: mitochondrial protein-transporting ATPase activity

description: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O = ADP + phosphate; drives the transport of proteins into the mitochondrion via the mitochondrial inner membrane translocase complex.


name: molybdenum incorporation into metallo-sulfur cluster

description: The incorporation of molybdenum into a metallo-sulfur cluster.


cellular response to glutathione

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glutathione stimulus.


name: formation of peptidyl-cystine persulfide by sulphur transfer from H2S

description: The modification of a peptidyl-cystine residue in a protein by the direct addition of H2S, followed by the removal of 2 protons to form peptidyl-cysteine persulfide.


glyoxal metabolic process

description: The chemical reactions and pathways involving glyoxal.


isoprenoid biosynthetic process

description: The chemical reactions and pathways resulting in the formation of an isoprenoid compound, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues.


name: 1-deoxy-D-xylulose 5-phosphate biosynthetic process

description: The chemical reactions and pathways resulting in the formation of 1-deoxy-D-xylulose 5-phosphate, the 5-phospho derivative of 1-deoxy-D-xylulose. 1-deoxy-D-xylulose 5-phosphate is an intermediate in the non-mevalonate pathway and a common precursor for isoprenoid, thiamin, and pyridoxol biosynthesis.


oxalate catabolic process

description: The chemical reactions and pathways resulting in the breakdown of oxalate, the organic acid ethanedioate.


gene expression

description: The process in which a gene's sequence is converted into a mature gene product (protein or RNA). This includes the production of an RNA transcript and its processing, as well as translation and maturation for protein-coding genes.


tryptophanyl-tRNA aminoacylation

description: The process of coupling tryptophan to tryptophanyl-tRNA, catalyzed by tryptophanyl-tRNA synthetase. The tryptophanyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2'-OH group of a tryptophan-accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification.


galactoxylomannan biosynthetic process

description: The chemical reactions and pathways resulting in the formation of the exopolysaccharide galactoxylomannan. Galactoxylomannan is produced by a pathogenic fungus and causes paralysis in some animals.


lysosomal membrane organization

description: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lysosomal membrane. A lysosomal membrane is the lipid bilayer surrounding the lysosome and separating its contents from the cell cytoplasm.


7S RNA binding

description: Binding to a 7S RNA, the RNA component of the signal recognition particle (SRP).


name: negative regulation of cellotriose metabolic process

description: Any process that stops, prevents or reduces the frequency, rate or extent of cellotriose metabolic process.


malonyl-CoA biosynthetic process

description: The chemical reactions and pathways resulting in the formation of malonyl-CoA, the S-malonyl derivative of coenzyme A.


name: formation of peptidyl-cystine persulfide by sulphur transfer from free cysteine

description: The modification of a peptidyl-cystine residue in a protein by the transfer of a sulfur atom from a free cysteine (in the process converting the free cysteine to alanine) to the peptidyl-cysteine to form peptidyl-cysteine persulfide.


name: phenol-containing compound metabolic process

description: The chemical reactions and pathways involving a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring.


name: secondary active transmembrane transporter activity

description: Enables the transfer of a solute from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy, not direct ATP coupling. Secondary active transporters include symporters and antiporters.


premeiotic DNA replication termination

description: Any DNA replication termination involved in meiotic cell cycle DNA replication.


peptidyl-pyrromethane cofactor linkage

description: The covalent binding of a pyrromethane (dipyrrin) cofactor to protein via the sulfur atom of cysteine forming dipyrrolylmethanemethyl-L-cysteine.


description: Catalysis of the reaction: P1-P6-bis(5'-adenosyl) hexaphosphate + H2O = AMP + adenosine 5'-pentaphosphate.


mitochondrial RNA surveillance

description: The set of processes involved in identifying and degrading defective or aberrant RNAs that takes place in the mitochondrion.


name: corticospinal neuron axon guidance through the cerebral peduncle

description: The process in which the migration of an axon growth cone of a pyramidal cell that is part of the corticospinal tract is directed after exiting the internal capsule through the cerebral peduncle in response to a combination of attractive and repulsive cues.


description: The methylation of 5-hydroxy-L-lysine to form peptidyl-N6,N6,N6-trimethyl-5-hydroxy-L-lysine.


name: regulation of cellodextrin catabolic process

description: Any process that modulates the frequency, rate or extent of cellodextrin catabolic process.


sevenless signaling pathway

description: The series of molecular signals initiated by an extracellular ligand binding to sevenless (sev; a receptor tyrosine kinase) on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.


name: cellular response to lipoprotein particle stimulus

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipoprotein particle stimulus.


name: activation-induced cell death of T cells

description: A T cell apoptotic process that occurs towards the end of the expansion phase following the initial activation of mature T cells by antigen and is triggered by T cell receptor stimulation and signals transmitted via various surface-expressed members of the TNF receptor family such as Fas ligand, Fas, and TNF and the p55 and p75 TNF receptors.


homocysteine metabolic process

description: The chemical reactions and pathways involving homocysteine, the amino acid alpha-amino-gamma-mercaptobutanoic acid. Homocysteine is an important intermediate in the metabolic reactions of its S-methyl derivative, methionine.


snRNA methylation

description: The posttranscriptional addition of methyl groups to specific residues in an snRNA molecule.


peptidyl-lysine malonylation

description: The addition of a malonyl group (CO-CH2-CO) to peptidyl-lysine to form N6-malonyl-L-lysine.


name: propionate transmembrane transporter activity

description: Enables the transfer of propionate from one side of a membrane to the other. Propionate (or propanoate) is the organic acid CH3-CH2-COOH.


description: The dehydration of peptidyl-S-carbamoyl-L-cysteine to form peptidyl-S-cyano-L-cysteine.


name: symbiont-mediated perturbation of host actin cytoskeleton via actin filament reorganization

description: The process in which an organism effects a change that impairs the structure or function of the host actin cytoskeleton by reorganizing the actin filaments, in a way that keeps the total filementous actin remains approximately constant. The host is defined as the larger of the organisms involved in a symbiotic interaction.


name: cardiac epithelial to mesenchymal transition

description: A transition where a cardiac epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.


name: protein localization to cytosolic proteasome complex

description: A process in which a protein is transported to, or maintained in, a location within a cytosolic proteasome complex.


name: protein localization to actin cortical patch

description: A process in which a protein is transported to, or maintained in, an actin cortical patch.


phlobaphene metabolic process

description: The chemical reactions and pathways involving phlobaphenes, red pigments with oligomeric or polymeric structure derived from the flavonoid intermediate flavan-4-ols.


regulation of G0 to G1 transition

description: A cell cycle process that modulates the rate or extent of the transition from the G0 quiescent state to the G1 phase.


7SK snRNA binding

description: Binding to a 7SK small nuclear RNA (7SK snRNA).


ectopic germ cell programmed cell death

description: Programmed cell death of an errant germ line cell that is outside the normal migratory path or ectopic to the gonad. This is an important mechanism of regulating germ cell survival within the embryo.


name: inhibitory C-type lectin receptor signaling pathway

description: The series of molecular signals initiated by an extracellular ligand binding to an inhibitory C-type lectin receptor capable of inhibiting an immune effector process contributing to an immune response.


heme oxidation

description: The chemical reactions and pathways resulting in the loss of electrons from one or more atoms in heme.


name: negative regulation of muscle cell apoptotic process

description: Any process that decreases the rate or frequency of muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a muscle cell and result in its death.


description: Catalysis of the reaction: 1,2-dihydroxyphenanthrene + UDP-glucose = 2-hydroxy-1-phenanthryl-beta-D-glucopyranoside + UDP.


name: symbiont entry into host cell via disruption of host cell envelope

description: The disruption by a symbiont of host cell envelope components to allow entry into the host cell.


R-loop processing

description: A DNA metabolic process that results in the disassembly of R-loops. R-loops are three-stranded nucleic acid structures consisitng of an RNA:DNA heteroduplex and a looped-out non-template strand. Aberrant formation and persistence of R-loops block transcription elongation and cause DNA damage. Mechanisms that resolve R-loops are essential for genome stability.


name: regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway

description: Any process that modulates the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing 2 (NOD2) pathway.


cellular response to diosgenin

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diosgenin stimulus.


propan-2-ol metabolic process

description: The chemical reactions and pathways involving propan-2-ol.


dehiscence

description: The opening of an anther, fruit or other structure, which permits the escape of reproductive bodies contained within it.


isoflavonoid metabolic process

description: The chemical reactions and pathways involving isoflavonoids, a group of water-soluble phenolic derivatives, isomeric with flavonoids, containing a flavan skeleton. They are differentiated from flavonoids by the point of attachment of the aromatic ring group.


cGMP-mediated signaling

description: An intracellular signaling cassette that starts with production of cyclic GMP (cGMP), and ends with activation of downstream effectors that further transmit the signal within the cell.


CCL19-activated CCR7 signaling pathway

description: The series of molecular signals initiated by the binding of the C-C chemokine CCL19 to a C-C chemokine type 7 receptor (CCR7) on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.


name: negative regulation of catecholamine metabolic process

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving catecholamine.


nucleic acid biosynthetic process

description: The biosynthetic process resulting in the formation of a nucleic acid.


CD27 signaling pathway

description: The series of molecular signals initiated by the binding of the cell surface receptor CD27 to its physiological ligand CD70, and ending with the regulation of a downstream cellular process, e.g. transcription.


glucocorticoid metabolic process

description: The chemical reactions and pathways involving glucocorticoids, hormonal C21 corticosteroids synthesized from cholesterol. Glucocorticoids act primarily on carbohydrate and protein metabolism, and have anti-inflammatory effects.


name: Mo-molybdopterin cofactor catabolic process

description: The chemical reactions and pathways resulting in the breakdown of the Mo-molybdopterin cofactor, essential for the catalytic activity of some enzymes. The cofactor consists of a mononuclear molybdenum (Mo) ion coordinated by one or two molybdopterin ligands.


name: negative regulation of fibroblast apoptotic process

description: Any process that stops, prevents or reduces the frequency, rate or extent of fibroblast apoptotic process.


name: positive regulation of T cell extravasation

description: Any process that activates or increases the frequency, rate or extent of T cell extravasation.


protein-heme P460 linkage

description: The linkage of protein to heme P460.


name: D-arabitol catabolic process to xylulose 5-phosphate

description: The chemical reactions and pathways resulting in the breakdown of D-arabitol to form xylulose 5-phosphate. D-arabitol is converted into D-xylulose, which is then phosphorylated to form D-xylulose-5-phosphate.


verruculogen biosynthetic process

description: The chemical reactions and pathways resulting in the formation of verruculogen.


anaerobic fructose catabolic process

description: The chemical reactions and pathways resulting in the breakdown of fructose that occurs in the absence of oxygen.


histidine N-acetyltransferase activity

description: Catalysis of the reaction: L-histidine + acetyl-CoA = N(alpha)-acetyl-L-histidine + CoA + H+.


engulfment of apoptotic cell

description: The removal of the apoptotic cell by phagocytosis, by a neighboring cell or by a phagocyte.


response to interleukin-6

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-6 stimulus.


protein-hormone receptor activity

description: Combining with a protein hormone to initiate a change in cell activity.


box H/ACA sno(s)RNA 3'-end processing

description: Any process involved in forming the mature 3' end of a box H/ACA RNA molecule.


peptide cross-linking via L-cystine

description: The oxidation of two peptidyl-cysteine residues to form a peptidyl-L-cystine (dicysteine) in which segments of peptide chain are linked by a disulfide bond; the cross-link may be between different or the same peptide chain.


gibberellin biosynthetic process

description: The chemical reactions and pathways resulting in the formation of gibberellin. Gibberellins are a class of highly modified terpenes that function as plant growth regulators.


description: The series of molecular signals initiated by interleukin-5 binding to its receptor on the surface of a cell, and ending with the regulation of a downstream cellular process, e.g. transcription.


name: phytochrome chromophore biosynthetic process

description: The chemical reactions and pathways resulting in the formation of the phytochrome chromophore. The phytochrome chromophore is a linear tetrapyrrolic prosthetic group covalently attached to the large soluble protein phytochrome. Light absorption by the phytochrome chromophore triggers photoconversion between two spectrally distinct forms of the photoreceptor: Pr, the red light absorbing form, and Pfr, the far red light absorbing form.


mRNA 3'-UTR AU-rich region binding

description: Binding to a region containing frequent adenine and uridine bases within the 3' untranslated region of a mRNA molecule or in pre-mRNA intron. The ARE-binding element consensus is UUAUUUAUU. ARE-binding proteins control the stability and/or translation of mRNAs.


regulation of mitotic cytokinesis

description: Any process that modulates the frequency, rate or extent of mitotic cytokinesis.


mannan biosynthetic process

description: The chemical reactions and pathways resulting in the formation of mannan, the main hemicellulose of soft (coniferous) wood, made up of D-mannose, D-glucose and D-galactose.


name: fatty acid beta-oxidation, unsaturated, even number

description: A fatty acid beta-oxidation pathway by which fatty acids having cis-double bonds on even-numbered carbons are degraded. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and ends when only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively).


name: inorganic molecular entity transmembrane transporter activity

description: Enables the transfer of an inorganic molecular entity from the outside of a cell to the inside of the cell across a membrane. An inorganic molecular entity is a molecular entity that contains no carbon.


name: cellular response to catecholamine stimulus

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a catecholamine stimulus. A catecholamine is any of a group of biogenic amines that includes 4-(2-aminoethyl)pyrocatechol [4-(2-aminoethyl)benzene-1,2-diol] and derivatives formed by substitution.


protein kinase activity

description: Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP.


tRNA N-acetyltransferase activity

description: Catalysis of the reaction: a cytidine in tRNA + acetyl-CoA + ATP + H2O = ADP + an N4-acetylcytidine in tRNA + CoA + H+ + phosphate.


terpenoid catabolic process

description: The chemical reactions and pathways resulting in the breakdown of terpenoids, any member of a class of compounds characterized by an isoprenoid chemical structure.


regulation of platelet aggregation

description: Any process that modulates the rate, frequency or extent of platelet aggregation. Platelet aggregation is the adhesion of one platelet to one or more other platelets via adhesion molecules.


description: The chemical reactions and pathways resulting in the breakdown of (+)-epi-alpha-bisabolol.


name: negative regulation of metabolic activity involved in hibernation

description: The slowing of metabolic processes to very low levels in order to conserve energy as a part of hibernation.


name: cellular biogenic amine catabolic process

description: The chemical reactions and pathways occurring at the level of individual cells resulting in the breakdown of biogenic amines, any of a group of naturally occurring, biologically active amines, such as norepinephrine, histamine, and serotonin, many of which act as neurotransmitters.


regulation of programmed cell death

description: Any process that modulates the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes.


name: histone H3K36 trimethyltransferase activity

description: Catalysis of the reaction: L-lysyl36-[histone H3] + 3 S-adenosyl-L-methionine = 3 H+ + N6,N6,N6-trimethyl-L-lysyl36-[histone H3] + 3 S-adenosyl-L-homocysteine. This reaction is the successive addition of three methyl groups to the lysine residue at position 36 of histone H3, producing histone H3K36me3.


name: semaphorin-plexin signaling pathway involved in neuron projection guidance

description: Any semaphorin-plexin signaling pathway that is involved in neuron projection guidance.


name: zeaxanthin bis(beta-D-glucoside) metabolic process

description: The chemical reactions and pathways involving zeaxanthin bis(beta-D-glucoside).


protein C-linked glycosylation

description: A protein glycosylation process in which a carbohydrate or carbohydrate derivative unit is added to a protein via a C atom.


name: positive regulation of DNA damage response, signal transduction by p53 class mediator

description: Any process that activates, maintains or increases the rate of the cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage.


name: glutamate:sodium symporter activity

description: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glutamate(out) + Na+(out) = glutamate(in) + Na+(in).


description: The acetylation of the N-terminal methionine of proteins to form the derivative N-acetyl-L-methionine.


methyltransferase activity

description: Catalysis of the transfer of a methyl group to an acceptor molecule.


name: mannose to fructose-6-phosphate catabolic process

description: The chemical reactions and pathways in which mannose, the aldohexose manno-hexose, is converted to fructose-6-phosphate.


coenzyme A metabolic process

description: The chemical reactions and pathways involving coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester.


name: positive regulation of acetylcholine metabolic process

description: Any process that increases the rate, frequency or extent of the chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues.


regulation of xylan catabolic process

description: Any process that modulates the frequency, rate or extent of xylan catabolic process.


name: positive regulation of catabolic process

description: Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances.


name: positive regulation of erythrocyte differentiation

description: Any process that activates or increases the frequency, rate or extent of erythrocyte differentiation.


name: iron-sulfur-molybdenum cofactor metabolic process

description: The chemical reactions and pathways involving iron-sulfur-molybdenum cofactor.


cellular response to cesium ion

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cesium stimulus.


undecan-2-one biosynthetic process

description: The chemical reactions and pathways resulting in the formation of undecan-2-one.


UDP-D-xylose metabolic process

description: The chemical reactions and pathways involving UDP-D-xylose, uridinediphosphoxylose, a substance composed of xylose in glycosidic linkage with uridine diphosphate.


name: adenylate cyclase-activating G protein-coupled bile acid receptor signaling pathway

description: An adenylate cyclase-activating G protein-coupled receptor signaling pathway initiated by a ligand binding to a bile acid receptor on the surface of the target cell, and ending with the regulation of a downstream cellular process.


protein localization to nucleoplasm

description: A process in which a protein is transported to, or maintained in, a location within the nucleoplasm.


stilbene catabolic process

description: The chemical reactions and pathways resulting in the breakdown of stilbenes, a class of polyketide compounds formed from cinnamic acid and three molecules of malonyl CoA.


thiocyanate metabolic process

description: The chemical reactions and pathways involving thiocyanate, the anion of thiocyanic acid, a toxic cyanide derivative commonly formed as a by-product in the production of gas for fuel, coke, and substances for chemical industries.


peptidyl-lysine methylation

description: The methylation of peptidyl-lysine to form either the mono-, di- or trimethylated derivative.


name: regulation of carbohydrate catabolic process

description: Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of carbohydrates.


name: negative regulation of response to wounding

description: Any process that stops, prevents or reduces the frequency, rate or extent of response to wounding.


description: The carbamylation of the N-terminal alanine of proteins to form the derivative N-carbamoyl-L-alanine.


description: The chemical reactions and pathways resulting in the formation of naphtho-gamma-pyrone.


7-methylguanosine cap hypermethylation

description: Hypermethylation of the 7-(mono)methylguanosine (m(7)G) cap structure at the 2' position of the guanosine residue to convert a mono-methylated cap to a 2,2,7-trimethylguanosine cap structure. This type of cap modification occurs on small nuclear RNAs (snRNAs) and small nucleolar RNAs (snoRNAs) and is dependent on prior guanine-N7 methylation.


antigen processing and presentation

description: The process in which an antigen-presenting cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex.


name: negative regulation of glucose transmembrane transport

description: Any process that decreases the frequency, rate or extent of glucose transport across a membrane. Glucose transport is the directed movement of the hexose monosaccharide glucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


name: Notch signaling pathway involved in camera-type eye photoreceptor fate commitment

description: The series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell that contributes to the commitment of a precursor cell to a eye photoreceptor fate.


response to type I interferon

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a type I interferon stimulus. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.


adenylyltransferase activity

description: Catalysis of the transfer of an adenylyl group to an acceptor.


regulation of viral transcription

description: Any process that modulates the frequency, rate or extent of the transcription of the viral genome.


name: negative regulation of microglial cell mediated cytotoxicity

description: Any process that stops, prevents or reduces the frequency, rate or extent of microglial cell mediated cytotoxicity.


name: negative regulation by host of viral genome replication

description: A process in which a host organism stops, prevents or reduces the frequency, rate or extent of viral genome replication.


name: positive regulation of adipose tissue development

description: Any process that activates or increases the frequency, rate or extent of adipose tissue development.


microtubule bundle formation

description: A process that results in a parallel arrangement of microtubules.


response to yeast

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a yeast species.


high-affinity IgA receptor activity

description: Combining with high affinity with an immunoglobulin of an IgA isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


name: anterograde trans-synaptic signaling by trans-synaptic protein complex

description: Cell-cell signaling from presynapse to postynapse, across the synaptic cleft, mediated by a trans-synaptic protein complex.


description: Catalysis of the reaction: poly(ribitol phosphate) + UDP-D-glucose = beta-D-glucosylpoly(ribitol phosphate) + UDP.


name: negative regulation of MyD88-dependent toll-like receptor signaling pathway

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of MyD88-dependent toll-like receptor signaling pathway.


name: positive regulation of mammary placode formation by mesenchymal-epithelial signaling

description: Any process that initiates the formation of a mammary placode through a mechanism that mediates the transfer of information from a mesenchymal cell to an epithelial cell resulting in the epithelial cell adopting the identity of a cell of the mammary placode.


neuropeptide F receptor activity

description: Combining with neuropeptide F and transmitting the signal within the cell to initiate a change in cell activity. Neuropeptide F is an arthropod peptide of more than 28 residues (typically 28-45) with a consensus C-terminal RxRFamide (commonly RPRFa, but also RVRFa.


rhamnogalacturonan II metabolic process

description: The chemical reactions and pathways involving rhamnogalacturonan II, a low molecular mass (5-10KDa) pectic polysaccharide. The backbone of RG-II contains at least 8 1,4-linked alpha-D-GalpA residues.


pyoverdine biosynthetic process

description: The chemical reactions and pathways resulting in the formation of the siderochrome pyoverdine.


name: negative regulation of alcohol biosynthetic process

description: Any process that stops, prevents or reduces the frequency, rate or extent of alcohol biosynthetic process.


glycolate metabolic process

description: The chemical reactions and pathways involving glycolate, the anion of hydroxyethanoic acid (glycolic acid).


interleukin-17 receptor activity

description: Combining with any member of the interleukin-17 family of cytokines and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


name: tolerance induction in gut-associated lymphoid tissue

description: Tolerance induction taking place in the gut-associated lymphoid tissue (GALT).


description: Catalysis of the reaction: isovitexin + UDP-D-glucose = H+ + isovitexin 2''-O-beta-D-glucoside + UDP.


fructan biosynthetic process

description: The chemical reactions and pathways resulting in the formation of fructan a polysaccharide consisting of fructose residues.


name: beta-hydroxybutyrate transmembrane transporter activity

description: Enables the transfer of beta-hydroxybutyrate from one side of a membrane to the other. Beta-hydroxybutyrate is the conjugate base of (R)-3-hydroxybutyric acid.


nucleobase catabolic process

description: The chemical reactions and pathways resulting in the breakdown of a nucleobase, a nitrogenous base that is a constituent of a nucleic acid.


name: positive regulation of adenosine receptor signaling pathway

description: Any process that activates or increases the frequency, rate or extent of the adenosine receptor signaling pathway. The adenosine receptor pathway is the series of molecular signals generated as a consequence of an adenosine receptor binding to one of its physiological ligands.


streptomycin metabolic process

description: The chemical reactions and pathways involving streptomycin, a commonly used antibiotic in cell culture media. It acts only on prokaryotes and blocks transition from initiation complex to chain elongating ribosome.


pyridine biosynthetic process

description: The chemical reactions and pathways resulting in the formation of pyridine, a nitrogenous base (C5H5N) obtained from the distillation of bone oil or coal tar, and by the decomposition of certain alkaloids, as a colorless liquid with a peculiar pungent odor.


glucuronoside metabolic process

description: The chemical reactions and pathways involving glucuronosides, any compound formed by combination in glycosidic linkage of a hydroxy compound with the anomeric carbon atom of a glucuronate.


monocyte extravasation

description: The migration of a monocyte from the blood vessels into the surrounding tissue.


cysteine-type endopeptidase activity

description: Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile.


name: pyrimidine dimer repair by nucleotide-excision repair

description: The repair of UV-induced T-T, C-T, and C-C dimers by the recognition and removal of the damaged DNA strand from the DNA helix as an oligonucleotide. The small gap left in the DNA helix is filled in by the sequential action of DNA polymerase and DNA ligase.


cellular response to flavonoid

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a flavonoid stimulus.


name: protein folding in endoplasmic reticulum

description: A protein folding process that takes place in the endoplasmic reticulum (ER). Secreted, plasma membrane and organelle proteins are folded in the ER, assisted by chaperones and foldases (protein disulphide isomerases), and additional factors required for optimal folding (ATP, Ca2+ and an oxidizing environment to allow disulfide bond formation).


name: glutathione-disulfide reductase (NADPH) activity

description: Catalysis of the reaction: 2 glutathione + NADP+ = glutathione disulfide + NADPH + H+.


name: negative regulation of humoral immune response

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of a humoral immune response.


name: bicyclic nitroimidazole metabolic process

description: The chemical reactions and pathways involving bicyclic nitroimidazoles, imidazole derivatives with two rings and a nitro group attached to one ring.


description: Catalysis of the reaction: acetyl-CoA + gentamicin C(1a) = N(2')-acetylgentamicin C(1a) + CoA + H+. This is acetylation of the 2'-amino group of the 6-deoxy-6-aminoglucose ring.


name: oxidative stress-induced premature senescence

description: A cellular senescence process associated with the dismantling of a cell as a response to oxidative stress, e.g. high levels of reactive oxygen species, such as superoxide anions, hydrogen peroxide, and hydroxyl radicals.


name: cysteine biosynthetic process via S-sulfo-L-cysteine

description: The chemical reactions and pathways resulting in the formation of cysteine, via the intermediate S-sulfo-L-cysteine.


description: The chemical reactions and pathways resulting in the breakdown of (17Z)-protosta-17(20),24-dien-3beta-ol.


name: positive regulation of transforming growth factor beta receptor signaling pathway

description: Any process that activates or increases the frequency, rate or extent of TGF-beta receptor signaling pathway activity.


name: positive regulation of DNA-templated DNA replication

description: Any process that activates or increases the frequency, rate or extent of DNA-templated DNA replication.


cellular response to resveratrol

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a resveratrol stimulus.


name: negative regulation of prostaglandin catabolic process

description: Any process that stops, prevents or reduces the frequency, rate or extent of prostaglandin catabolic process.


name: negative regulation of growth hormone receptor signaling pathway

description: Any process that decreases the rate, frequency or extent of the growth hormone receptor signaling pathway. The growth hormone receptor signaling pathway is the series of molecular signals generated as a consequence of growth hormone receptor binding to its physiological ligand.


interleukin-16 production

description: The appearance of interleukin-16 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


bradykinin catabolic process

description: The chemical reactions and pathways resulting in the breakdown of the peptide bradykinin.


sperm plasma membrane disassembly

description: The gradual disintegration of the sperm plasma membrane following insemination. This process is seen in Drosophila after entry of the entire sperm, surrounded by its plasma membrane, into the egg.


U6 snRNA binding

description: Binding to a U6 small nuclear RNA (U6 snRNA).


GUU codon-amino acid adaptor activity

description: A triplet codon-amino acid adaptor activity that recognizes a GUU codon.


interleukin-37 production

description: The appearance of interleukin-37 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


name: organic heteropentacyclic compound catabolic process

description: The chemical reactions and pathways resulting in the breakdown of organic heteropentacyclic compound.


IDP catabolic process

description: The chemical reactions and pathways resulting in the breakdown of IDP, inosine 5'-diphosphate.


dUTP metabolic process

description: The chemical reactions and pathways involving dUTP, deoxyuridine (5'-)triphosphate.


peptidyl-lysine dimethylation

description: The methylation of peptidyl-lysine to form peptidyl-N6,N6-dimethyl-L-lysine.


auxin-activated signaling pathway

description: The series of molecular signals generated by the binding of the plant hormone auxin to a receptor, and ending with modulation of a downstream cellular process, e.g. transcription.


name: mesenchymal smoothened signaling pathway involved in prostate gland development

description: The series of molecular signals generated as a consequence of activation of the transmembrane Smoothened-type protein in the mesenchymal cells of the prostate that contribute to the progression of the prostate over time. This process contributes to lung development.


cytidine salvage

description: Any process that generates cytidine, cytosine riboside, from derivatives of it without de novo synthesis.


hexose metabolic process

description: The chemical reactions and pathways involving a hexose, any monosaccharide with a chain of six carbon atoms in the molecule.


name: positive regulation of cell-cell adhesion

description: Any process that activates or increases the rate or extent of cell adhesion to another cell.


name: positive regulation of flavonoid biosynthetic process

description: Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of flavonoids.


name: positive regulation of neutrophil mediated killing of gram-negative bacterium

description: Any process that increases the frequency, rate or extent of the directed killing of a gram-negative bacterium by a neutrophil.


thiocyanate catabolic process

description: The chemical reactions and pathways resulting in the breakdown of thiocyanate, any anion of thiocyanic acid.


lipid modification

description: The covalent alteration of one or more fatty acids in a lipid, resulting in a change in the properties of the lipid.


proteinase-activated receptor activity

description: A G protein-coupled receptor activity that is activated by cleavage by a serine protease, exposing a tethered ligand corresponding to the new N-terminus, which binds to the receptor and activates it.


syringal lignin biosynthetic process

description: The chemical reactions and pathways resulting in the formation of syringal lignin.


name: negative regulation of lactose biosynthetic process

description: Any process that stops, prevents or reduces the frequency, rate or extent of lactose biosynthetic process.


glycosyl compound biosynthetic process

description: The chemical reactions and pathways resulting in the formation of glycosyl compound.


intestinal phytosterol absorption

description: A process in which phytosterols are taken up from the contents of the intestine.


name: guanosine pentaphosphate catabolic process

description: The chemical reactions and pathways resulting in the breakdown of guanine pentaphosphate (5'-pppGpp-3'), a derivative of guanine riboside with five phosphates.


migration in host

description: The directional movement of an organism from one place to another within its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.


cyanamide metabolic process

description: The chemical reactions and pathways involving cyanamide, NCNH2, a cyanide compound which has been used as a fertilizer, defoliant and in many manufacturing processes. It often occurs as the calcium salt, sometimes also referred to as cyanamide. The citrated calcium salt is used in the treatment of alcoholism.


response to nickel cation

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nickel cation stimulus.


name: activating MHC class I receptor activity

description: Combining with a MHC class I protein complex to mediate signaling that activates a lymphocyte.


name: gastric inhibitory peptide receptor activity

description: Combining with gastric inhibitory peptide (GIP) and transmitting the signal across the membrane to activate an associated G-protein.


snRNA binding

description: Binding to a small nuclear RNA (snRNA).


name: symbiont-mediated suppression of host autophagy

description: A process in which a symbiont inhibits or disrupts the normal execution of autophagy in the host cell. The host is defined as the larger of the organisms involved in a symbiotic interaction.


pyloric canal smooth muscle contraction

description: A process in which force is generated within gastric smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the distal part of the pylorus between the pyloric antrum and the pyloric sphincter.


citrulline metabolic process

description: The chemical reactions and pathways involving citrulline, N5-carbamoyl-L-ornithine, an alpha amino acid not found in proteins.


perception of rate of movement

description: The series of events by which an organism senses the speed and direction of movement of the body and its parts.


telomeric 3' overhang formation

description: The formation of the single stranded telomeric 3' overhang, a conserved feature that ranges in length from 12 nt in budding yeast to approximately 500 nt in humans.


cellular response to putrescine

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a putrescine stimulus.


name: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen

description: Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from each of two donors, and molecular oxygen is reduced or incorporated into a donor.


name: modulation of process of another organism

description: The process in which an organism effects a change in the structure or processes of another organism.


name: serine family amino acid metabolic process

description: The chemical reactions and pathways involving amino acids of the serine family, comprising cysteine, glycine, homoserine, selenocysteine and serine.


purine nucleoside metabolic process

description: The chemical reactions and pathways involving one of a family of organic molecules consisting of a purine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside).


tyramine receptor activity

description: Combining with the biogenic amine tyramine to initiate a change in cell activity. Tyramine is a sympathomimetic amine derived from tyrosine with an action resembling that of epinephrine.


trinitrotoluene metabolic process

description: The chemical reactions and pathways involving trinitrotoluene, a methylated benzene molecule with three NO2 groups attached to it. This includes the explosive TNT, 1-methyl-2,4,6-trinitrobenzene.


name: stomach fundus smooth muscle contraction

description: A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the fundus of stomach. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The fundus is the portion of the stomach that lies above the cardiac notch.


name: lymphocyte migration into lymphoid organs

description: The movement of a lymphocyte within the lymphatic system into lymphoid organs such as lymph nodes, spleen or Peyer's patches, and its subsequent positioning within defined functional compartments such as sites of cell activation by antigen.


interleukin-28A production

description: The appearance of interleukin-28A due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


description: The chemical reactions and pathways resulting in the formation of a tetrahydromethanopterin.


interleukin-18 receptor activity

description: Combining with interleukin-18 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


alkane catabolic process

description: The chemical reactions and pathways resulting in the breakdown of an alkane, any acyclic branched or unbranched hydrocarbon having the general formula CnH2n+2.


name: G protein-coupled dopamine receptor signaling pathway

description: A G protein-coupled receptor signaling pathway initiated by a dopamine binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process.


name: positive regulation of regulatory T cell differentiation

description: Any process that activates or increases the frequency, rate or extent of differentiation of regulatory T cells.


name: connective tissue growth factor production

description: The appearance of connective tissue growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


dCMP catabolic process

description: The chemical reactions and pathways resulting in the breakdown of dCMP, deoxycytidine monophosphate.


cellular response to lectin

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lectin stimulus. A lectin is a carbohydrate-binding protein, highly specific for binding sugar moieties.


name: negative regulation of response to type II interferon

description: Any process that decreases the rate, frequency or extent of a response to type II interferon (interferon-gamma). Response to interferon gamma is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-gamma stimulus.


nephron tubule formation

description: The developmental process pertaining to the initial formation of a nephron tubule from unspecified parts. A nephron tubule is an epithelial tube that is part of the nephron, the functional part of the kidney.


name: granzyme B localization to T cell secretory granule

description: Any process in which the protease granzyme B is transported to, or maintained in, a location within a secretory granule in a T cell.


3-cyano-L-alanine biosynthetic process

description: The chemical reactions and pathways resulting in the formation of 3-cyano-L-alanine.


name: circadian sleep/wake cycle, non-REM sleep

description: All sleep stages in the circadian sleep/wake cycle other than REM sleep. These stages are characterized by a slowing of brain waves and other physiological functions.


bile acid signaling pathway

description: The series of molecular signals initiated by bile acid binding to its receptor, and ending with the regulation of a downstream cellular process, e.g. transcription.


stress response to zinc ion

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis caused by a zinc ion stimulus.


name: peptidyl-aspartic acid hydroxylation to form L-erythro-beta-hydroxyaspartic acid

description: The hydroxylation of peptidyl-aspartic acid to form peptidyl-L-erythro-beta-hydroxyaspartic acid; catalyzed by peptide-aspartate beta-dioxygenase (EC:1.14.11.16).


name: histone H4K20 monomethyltransferase activity

description: Catalysis of the reaction: L-lysyl20-[histone H4] + S-adenosyl-L-methionine = H+ + N6-methyl-L-lysyl20-[histone H4] + S-adenosyl-L-homocysteine. This reaction is the addition of a methyl group to the unmethylated lysine residue at position 20 of histone H4, producing histone H4K20me.


vitamin B6 catabolic process

description: The chemical reactions and pathways resulting in the breakdown of any of the vitamin B6 compounds; pyridoxal, pyridoxamine and pyridoxine and the active form, pyridoxal phosphate.


snRNA metabolic process

description: The chemical reactions and pathways involving snRNA, small nuclear RNA, any of various low-molecular-mass RNA molecules found in the eukaryotic nucleus as components of the small nuclear ribonucleoprotein.


synaptic signaling via neuropeptide

description: Cell-cell signaling to or from a synapse, mediated by a peptide.


name: ATPase-coupled carboxylic acid transmembrane transporter activity

description: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + carboxylic acid(out/in) = ADP + phosphate + carboxylic acid(in/out).


endoplasmic reticulum membrane fusion

description: The joining of 2 or more lipid bilayer membranes that surround the endoplasmic reticulum.


tatiopterin biosynthetic process

description: The chemical reactions and pathways resulting in the formation of tatiopterin.


protein K27-linked deubiquitination

description: A protein deubiquitination process in which a K27-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 27 of the ubiquitin monomers, is removed from a protein.


cellular response to sodium phosphate

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sodium phosphate stimulus.


name: nucleoside monophosphate metabolic process

description: The chemical reactions and pathways involving a nucleoside monophosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with phosphate on the sugar.


cell wall integrity MAPK cascade

description: A MAPK cascade containing at least the SLT2 (S.cerevisiae)/Pmk1 (S.pombe) MAP kinase. It starts with the activation of an upstream MAP4K, and continues with the consecutive activation of a MAP3K and a MAP2K. The upstream MAP4K is activated following the detection of stretching of the plasma membrane or alterations of its connections to the cell wall by membrane sensors.


name: positive regulation of apoptotic process in bone marrow cell

description: Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process in the bone marrow.


paranodal junction assembly

description: Formation of the junction between an axon and the glial cell that forms the myelin sheath. Paranodal junctions form at each paranode, i.e. at the ends of the unmyelinated nodes of Ranvier.


coenzyme M metabolic process

description: The chemical reactions and pathways involving coenzyme M (2-thioethansulfonate), a coenzyme involved in the utilization of methane by methanogenic prokaryotes.


2-dehydro-3-deoxygluconokinase activity

description: Catalysis of the reaction: 2-dehydro-3-deoxy-D-gluconate + ATP = 2-dehydro-3-deoxy-6-phospho-D-gluconate + ADP + 2 H+.


name: isoquinoline alkaloid biosynthetic process

description: The chemical reactions and pathways resulting in the formation of isoquinoline alkaloids, alkaloid compounds that contain bicyclic N-containing aromatic rings and are derived from a 3,4-dihydroxytyramine (dopamine) precursor that undergoes a Schiff base addition with aldehydes of different origin.


memory T cell extravasation

description: The migration of a memory T cell from the blood vessels into the surrounding tissue. A memory T cell is a distinctly differentiated long-lived T cell that has the phenotype CD45RO-positive and CD127-positive.


name: regulation of apoptotic process involved in metanephric nephron tubule development

description: Any process that modulates the frequency, rate or extent of apoptotic process involved in metanephric nephron tubule development.


name: antigen processing and presentation of endogenous peptide antigen via MHC class I

description: The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class I protein complex. The peptide antigen is typically, but not always, processed from a whole protein. Class I here refers to classical class I molecules.


flavonoid metabolic process

description: The chemical reactions and pathways involving flavonoids, a group of water-soluble phenolic derivatives containing a flavan skeleton including flavones, flavonols and flavanoids, and anthocyanins.


nucleologenesis

description: A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a nucleolus, a small, dense body one or more of which are present in the nucleus of eukaryotic cells.


name: positive regulation of muscle cell apoptotic process

description: Any process that increases the rate or frequency of muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a muscle cell and result in its death.


ta-siRNA processing

description: A process leading to the generation of a functional trans-acting small interfering RNA (ta-siRNA). ta-siRNAs function like miRNAs to guide cleavage of target mRNAs.


name: symbiont-mediated suppression of host cGAS-STING signal transduction

description: A process in which a virus interferes with, inhibits or disrupt a cGAS/STING signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.


UTP diphosphatase activity

description: Catalysis of the reaction: UTP + H2O = UMP + H+ + diphosphate.


description: The 2-hydroxyisobutyrylation of a lysine residue in a protein.


name: protein localization to mitotic spindle midzone

description: A process in which a protein is transported to, or maintained in, a location within a mitotic spindle midzone.


UDP-D-apiose biosynthetic process

description: The chemical reactions and pathways resulting in the formation of UDP-D-apiose, uridinediphosphoapicose, a substance composed of apiose in glycosidic linkage with uridine diphosphate.


thylakoid membrane organization

description: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the thylakoid membrane.


name: positive regulation of adenylate cyclase-activating adrenergic receptor signaling pathway

description: Any process that activates or increases the frequency, rate or extent of the adenylate cyclase-activating adrenergic receptor protein signaling pathway. An adrenergic receptor signaling pathway is the series of molecular signals generated as a consequence of an adrenergic receptor binding to one of its physiological ligands.


cellular response to phenylpropanoid

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a phenylpropanoid stimulus.


cephalosporin C catabolic process

description: The chemical reactions and pathways resulting in the breakdown of cephalosporin C.


vacuole inheritance

description: The distribution of vacuoles into daughter cells after mitosis or meiosis, mediated by interactions between vacuoles and the cytoskeleton.


N-methyltransferase activity

description: Catalysis of the transfer of a methyl group to the nitrogen atom of an acceptor molecule.


protein autoubiquitination

description: The ubiquitination by a protein of one or more of its own amino acid residues, or residues on an identical protein. Ubiquitination occurs on the lysine residue by formation of an isopeptide crosslink.


name: cellular response to 4-nitroquinoline N-oxide

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 4-nitroquinoline N-oxide stimulus.


name: putrescine biosynthetic process from arginine

description: The chemical reactions and pathways resulting in the formation of putrescine, 1,4-diaminobutane, from other compounds, including arginine.


name: positive regulation of mitotic cytokinetic process

description: Any process that activates or increases the frequency, rate or extent of mitotic cytokinetic process.


cellular response to sulfate starvation

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of sulfate.


ATP metabolic process

description: The chemical reactions and pathways involving ATP, adenosine triphosphate, a universally important coenzyme and enzyme regulator.


name: adhesion of symbiont hyphopodium to host

description: The attachment of a hyphopodium of the symbiont to its host via adhesion molecules. The host is defined as the larger of the organisms involved in a symbiotic interaction.


name: mesenchymal-epithelial cell signaling involved in prostate gland development

description: Any process that mediates the transfer of information from a mesenchymal cell to an epithelial cell where it is received and interpreted contributing to the progression of the prostate gland over time.


glycol metabolic process

description: The chemical reactions and pathways involving glycol, a diol in which the two hydroxy groups are on different carbon atoms, usually but not necessarily adjacent.


name: negative regulation of signal transduction in absence of ligand

description: Any process that stops, prevents or reduces the frequency, rate or extent of signal transduction in absence of ligand.


name: envenomation resulting in fibrinolysis in another organism

description: The process which begins with venom being forced into an organism by the bite or sting of another organism, and ends with fibrinolysis, a process that solubilizes fibrin, chiefly by the proteolytic action of plasmin, in the bloodstream of the bitten/stung organism.


mitochondrial outer membrane fusion

description: The membrane organization process that joins two mitochondrial outer membranes to form a single membrane.


rhamnulokinase activity

description: Catalysis of the reaction: ATP + L-rhamnulose = ADP + L-rhamnulose 1-phosphate.


name: platelet-derived growth factor receptor signaling pathway

description: The series of molecular signals initiated by a ligand binding to a platelet-derived growth factor receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.


regulation of heme biosynthetic process

description: Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of heme.


neuropeptide receptor activity

description: Combining with a neuropeptide to initiate a change in cell activity.


name: cell wall polysaccharide biosynthetic process

description: The chemical reactions and pathways resulting in the formation of a polysaccharide destined to form part of a cell wall.


urinary tract smooth muscle contraction

description: A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the urinary tract. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The urinary tract consists of organs of the body that produce and discharge urine. These include the kidneys, ureters, bladder, and urethra.


uracil salvage

description: Any process that generates uracil, 2,4-dioxopyrimidine, from derivatives of it without de novo synthesis.


nicotine metabolic process

description: The chemical reactions and pathways involving nicotine, (S)(-)-3-(1-methyl-2-pyrrolidinyl)pyridine.


name: symbiont-mediated perturbation of host MAPK cascade

description: A process in which a symbiont alters or subverts a MAP kinase-mediated signal transduction pathway in its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.


description: The chemical reactions and pathways involving 18-methylnonadec-1-ene.


name: aerobic respiration, using ferrous ions as electron donor

description: The metabolic process in which ferrous ions (Fe2+) are oxidized to ferric ions (Fe3+) to generate energy, coupled to the reduction of carbon dioxide.