name: regulation of CD8-positive, alpha-beta T cell extravasation

description: Any process that modulates the frequency, rate or extent of CD8-positive, alpha-beta T cell extravasation.


pullulan biosynthetic process

category: biolink:BiologicalProcess biolink:Occurrent biolink:OntologyClass biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: The chemical reactions and pathways resulting in the formation of pullulan, a neutral linear polysaccharide composed of repeating units of maltotriose joined by alpha-(1,6)-linkages.


name: mitochondrial outer membrane permeabilization

description: The process by which the mitochondrial outer membrane becomes permeable to the passing of proteins and other molecules from the intermembrane space to the cytosol as part of the apoptotic signaling pathway.


name: poly(glycerol phosphate) teichoic acid biosynthetic process

description: The chemical reactions and pathways resulting in the formation of poly(glycerol phosphate) teichoic acid.


trace-amine receptor activity

category: biolink:MolecularActivity biolink:Occurrent biolink:OntologyClass biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: Combining with a trace amine to initiate a change in cell activity. Trace amines are biogenic amines that are synthesized from aromatic amino acids and are substrates for monoamine oxidase, and are therefore detectable only at trace levels in mammals.


name: nucleoside diphosphate metabolic process

description: The chemical reactions and pathways involving a nucleoside diphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with diphosphate on the sugar.


name: negative regulation of toll-like receptor 21 signaling pathway

description: Any process that stops, prevents or reduces the frequency, rate or extent of toll-like receptor 21 signaling pathway.


xylose catabolic process to ethanol

description: The anaerobic chemical reactions and pathways resulting in the breakdown of xylose, an aldopentose, where one of the resulting products is ethanol.


heteroduplex formation

description: The formation of a stable duplex DNA that contains one strand from each of the two recombining DNA molecules.


regulation of wax biosynthetic process

description: Any process that modulates the frequency, rate or extent of wax biosynthetic process.


hydroxylysine catabolic process

description: The chemical reactions and pathways resulting in the breakdown of hydroxylysine (5-hydroxy-2,6-diaminohexanoic acid), a chiral alpha-amino acid.


myeloid cell apoptotic process

description: Any apoptotic process in a myeloid cell, a cell of the monocyte, granulocyte, mast cell, megakaryocyte, or erythroid lineage.


name: cellular detoxification of hydrogen peroxide

description: Any process that reduces or removes the toxicity of hydrogen peroxide in a cell. These include transport of hydrogen peroxide away from sensitive areas and to compartments or complexes whose purpose is sequestration.


description: Catalysis of the reaction: 3-O-[N-acetyl-beta-D-glucosaminyl-(1->3)-N-acetyl-alpha-D-galactosaminyl]-L-threonyl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = 3-O-[N-acetyl-beta-D-glucosaminyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->6)]-N-acetyl-alpha-D-galactosaminyl]-L-threonyl-[protein] + H+ + UDP.


lysine metabolic process

description: The chemical reactions and pathways involving lysine, 2,6-diaminohexanoic acid.


name: envenomation resulting in modulation of acid-sensing ion channel activity in another organism

description: A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant change in the activity of an acid-sensing ion channel (ASIC) in the bitten organism.


name: iron incorporation into iron-sulfur cluster via tris-L-cysteinyl-L-N1'-histidino tetrairon tetrasulfide

description: The incorporation of iron into a 4Fe-4S iron-sulfur cluster via tris-L-cysteinyl-L-N1'-histidino tetrairon tetrasulfide.


name: propionate metabolic process, methylcitrate cycle

description: The chemical reactions and pathways involving propionate that occur in the methylcitrate cycle.


name: positive regulation of gibberellic acid mediated signaling pathway

description: Any process that activates or increases the frequency, rate or extent of gibberellic acid mediated signaling activity.


N-acetyltransferase activity

description: Catalysis of the transfer of an acetyl group to a nitrogen atom on the acceptor molecule.


phenylpropanoid biosynthetic process

description: The chemical reactions and pathways resulting in the formation of aromatic derivatives of trans-cinnamic acid.


interleukin-13 production

description: The appearance of interleukin-13 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


name: negative regulation of anterior neural cell fate commitment of the neural plate by fibroblast growth factor receptor signaling pathway

category: biolink:Pathway biolink:OntologyClass biolink:BiologicalProcess biolink:Occurrent biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: The series of molecular signals that stops, prevents or reduces the frequency or rate at which cell adopts an anterior neural cell fate, generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands.


name: ganglioside biosynthetic process via lactosylceramide

description: The chemical reactions and pathways resulting in the formation of gangliosides that begins with the formation of lactosylceramides, Gal-beta-(1->4)-Glc-beta-(1->1') ceramides, any compound formed by the replacement of the glycosidic C1 hydroxyl group of lactose by a ceramide group.


name: positive regulation of erythrocyte aggregation

description: Any process that activates or increases the frequency, rate, or extent of erythrocyte aggregation.


description: The formylation of the N-terminal glycine of proteins to form the derivative N-formylglycine.


G1 phase

description: The cell cycle 'gap' phase which is the interval between the completion of DNA segregation (usually by mitosis or meiosis) and the beginning of DNA synthesis.


name: negative regulation of eosinophil extravasation

description: Any process that stops, prevents or reduces the frequency, rate or extent of eosinophil extravasation.


synaptic vesicle coating

description: The formation of clathrin coated pits in the presynaptic membrane endocytic zone, triggered by the presence of high concentrations of synaptic vesicle components. This process leads to, but does not include budding of the membrane to form new vesicles.


protein K29-linked ubiquitination

description: A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 29 of the ubiquitin monomers, is added to a protein. K29-linked ubiquitination targets the substrate protein for degradation.


name: gastrulation involving germ band extension

description: A complex and coordinated series of cellular movements, including germ band extension, that occurs at the end of cleavage during embryonic development. An example of this process is found in Drosophila melanogaster.


name: positive regulation of chemokine-mediated signaling pathway

description: Any process that increases the rate, frequency or extent of a chemokine-mediated signaling pathway.


name: G protein-coupled glucose receptor activity

description: Combining with an extracellular glucose molecule and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.


name: regulation of blood pressure by chemoreceptor signaling pathway

description: A series of reactions within the cell that occur as a result of a single trigger reaction or compound interacting with a chemoreceptor resulting in a modulation of the force with which blood travels through the circulatory system. Chemoreceptors respond to oxygen, carbon dioxide and hydrogen ions.


putrescine acetylation

description: The modification of putrescine by addition of acetyl groups.


name: smoothened signaling pathway involved in regulation of secondary heart field cardioblast proliferation

description: The series of molecular signals generated as a consequence of activation of the transmembrane protein Smoothened contributing to the modulation of the frequency, rate or extent of cardioblast proliferation in the secondary heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.


name: regulation of vascular associated smooth muscle cell migration

description: Any process that modulates the frequency, rate or extent of vascular associated smooth muscle cell migration.


name: distal stomach smooth muscle contraction

description: A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the distal stomach. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The distal stomach is composed of the lower body and antrum and develops strong peristaltic phasic contractions that increase in amplitude as they propagate toward the pylorus.


name: isopentenyl diphosphate biosynthetic process, mevalonate pathway

description: The chemical reactions and pathways resulting in the formation of isopentenyl diphosphate, via the intermediate mevalonate. This pathway converts acetate, in the form of acetyl-CoA, to isopentenyl diphosphate (IPP), the fundamental unit in isoprenoid biosynthesis, through a series of mevalonate intermediates.


name: protein localization to ciliary inversin compartment

description: A process in which a protein is transported to, or maintained in, a location within a ciliary inversin compartment.


cellular response to chloroquine

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chloroquine stimulus.


name: positive regulation of phytoalexin metabolic process

description: Any process that activates, maintains or increases the frequency, rate or extent of phytoalexin metabolism, the chemical reactions and pathways involving phytoalexins.


fatty alcohol catabolic process

description: The chemical reactions and pathways resulting in the breakdown of fatty alcohol.


description: Catalysis of the reaction: nicotinate + UDP-D-glucose = O-D-glucosylnicotinate + UDP.


negative regulation of anoikis

description: Any process that stops, prevents or reduces the frequency, rate or extent of anoikis.


name: organic phosphonate biosynthetic process

description: The chemical reactions and pathways resulting in the formation of phosphonates, any organic compound containing one or more C-PO(OH)2 or C-PO(OR)2 (with R=alkyl, aryl) groups. Synthesis of phosphonic acid itself, an inorganic compound without the biochemically relevant C-P bond, is not included.


guanosine salvage

description: Any process that generates guanosine, guanine riboside, from derivatives of it without de novo synthesis.


pteridine metabolic process

description: The chemical reactions and pathways involving pteridine, pyrazino(2,3-dipyrimidine), the parent structure of pterins and the pteroyl group.


N-formyl peptide receptor activity

description: Combining with an N-formyl peptide to initiate a change in cell activity.


description: A phytochelatin metabolic process in which a metal and exogenous sulfur are incorporated with phytochelatin to form a complex.


regulation of mitotic recombination

description: Any process that modulates the frequency, rate or extent of DNA recombination during mitosis.


name: regulation of mitotic DNA damage checkpoint

description: Any process that modulates the frequency, rate or extent of mitotic DNA damage checkpoint.


name: mesenchymal-epithelial cell signaling involved in prostate induction

description: Signaling at short range from urogenital sinus mesenchymal cells to cells of the urogenital epithelium resulting in the epithelial cells adopting a prostatic fate.


name: jasmonic acid and ethylene-dependent systemic resistance, jasmonic acid mediated signaling pathway

description: The series of molecular signals mediated by jasmonic acid involved in jasmonic acid/ethylene (ethene) dependent systemic resistance.


name: tungsten incorporation via L-selenocysteinyl tungsten bis(molybdopterin guanine dinucleotide)

description: The incorporation of tungsten into a protein via L-selenocysteinyl tungsten bis(molybdopterin guanine dinucleotide).


regulation of peptide transport

description: Any process that modulates the frequency, rate or extent of the directed movement of peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


release from viral latency

description: The process by which a virus begins to replicate following a latency replication decision (switch).


organosilicon catabolic process

description: The chemical reactions and pathways resulting in the breakdown of organosilicons, any organic compound that contains silicon.


positive regulation of defense response

description: Any process that activates or increases the frequency, rate or extent of a defense response.


gibberellin 12 metabolic process

description: The chemical reactions and pathways involving gibberellin 12, (1R,2S,3S,4R,8S,9S,12R)-4,8-dimethyl-13-methylidenetetracyclo[10.2.1.01,9.03,8]pentadecane-2,4-dicarboxylic acid 1meta,4a-dimethyl-8-methylidene-4aalpha,4bbeta-gibbane-1alpha,10beta-dicarboxylic acid.


phytanic acid metabolic process

description: The chemical reactions and pathways involving phytanic acid.


Group II intron splicing

description: The splicing of Group II introns. This occurs by a ribozymic mechanism where the intron sequence forms a distinct 3D structure, characteristic of Group II introns and containing splice site consensus sequences, that is involved in catalyzing the splicing reactions, though protein factors are also required in vivo. Splicing occurs by a series of two transesterification reactions (mechanistically similar to those for splicing of nuclear mRNAs) initiated by a bulged adenosine residue within the intron sequence as the initiating nucleophile. The intron is excised as a lariat.


RNA nucleotide insertion

description: The modification of an RNA molecule by insertion of one or more nucleotides.


name: 5-phosphoribosyl 1-pyrophosphate pyrophosphatase activity

description: Catalysis of the reaction: 5-phospho-alpha-D-ribose 1-diphosphate + H2O = ribose 1,5 bisphosphate + phosphate + H+.


3'-5' DNA helicase activity

description: Unwinding a DNA helix in the direction 5' to 3', driven by ATP hydrolysis.


name: negative regulation of signal transduction by p53 class mediator

description: Any process that stops, prevents or reduces the frequency, rate or extent of signal transduction by p53 class mediator.


name: extracellular polysaccharide catabolic process involved in ascospore release from ascus

description: The chemical reactions and pathways resulting in the breakdown of polysaccharides in the ascus wall that contributes to the release of ascospores from the ascus.


name: regulation of mitotic spindle checkpoint

description: Any process that modulates the frequency, rate or extent of mitotic spindle checkpoint.


description: Catalysis of the transfer of a palmitoyl group to the N6 nitrogen atom on a lysine residue of a peptide or protein molecule.


bile acid conjugation

description: The process in which bile acids are covalently linked to taurine or glycine.


methylmercury biosynthetic process

description: The chemical reactions and pathways resulting in the formation of methylmercury (MeHg+), a highly toxic organometal.


description: Catalysis of the reaction: 2-hydroxyisobutyryl-CoA + lysine in peptide = CoA + N-2-hydroxyisobutyryl-lysine-peptide.


cellular process

description: Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.


shamixanthone biosynthetic process

description: The chemical reactions and pathways resulting in the formation of shamixanthone.


taxis

description: The directed movement of a motile cell or organism in response to an external stimulus.


exit from host cell

description: The movement of an organism out of a cell of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.


name: fatty acid beta-oxidation, unsaturated, even number, epimerase pathway

description: A fatty acid beta-oxidation pathway by which fatty acids having cis-double bonds on even-numbered carbons are degraded. In this pathway, the intermediate 2,4-dienoyl-CoA is converted to cis-2-enoyl-CoA through one more cycle of the core beta-oxidation pathway. Cis-2-enoyl-CoA cannot be completely degraded via the core beta-oxidation pathway because hydratation of cis-2-enoyl-CoA yields D-3-hydroxyacyl-CoA, which is not a substrate for 3-hydroxylacyl-CoA dehydrogenase. Cis-2-enoyl-CoA must enter the so-called epimerase pathway, which involves converting D-3-hydroxyacyl-CoA to L-3-hydroxyacyl-CoA by 3-hydroxylacyl-CoA epimerase or by two stereo-specific enoyl-CoA hydratases. L-3-hydroxyacyl-CoA then returns to the core beta-oxidation pathway. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and ends when only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively).


description: The trimethylation of the N-terminal serine of proteins to form the derivative N,N,N-trimethylserine.


name: extracellular matrix-granule cell signaling involved in regulation of granule cell precursor proliferation

description: The process that mediates the transfer of information from the extracellular matrix to granule cell precursors resulting in a decrease in rate of granule cell precursor cell proliferation.


name: negative regulation of glial cell apoptotic process

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of glial cell apoptotic process.


superinfection exclusion

description: The process by which a preexisting viral infection prevents a secondary infection with the same or a closely related virus. Typically some aspect of viral entry is inhibited, but post entry mechanisms have also been documented.


description: Catalysis of the reaction: sn-glycerol 3-phosphate + UDP-D-galactose = 1-O-alpha-D-galactosyl-sn-glycerol 3-phosphate + H+ + UDP.


proteolysis

description: The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.


name: symbiont-mediated perturbation of host G protein-coupled receptor signal transduction pathway

description: A process by which a symbiont alters or subverts the normal execution of a host G protein-coupled receptor signal transduction pathway. The host is defined as the larger of the organisms involved in a symbiotic interaction.


RNA strand annealing activity

description: An activity that facilitates the formation of a complementary double-stranded RNA molecule.


name: positive regulation of mononuclear cell migration

description: Any process that increases the rate, frequency or extent of mononuclear cell migration. Mononuclear cell migration is the movement of a mononuclear cell within or between different tissues and organs of the body.


cellular response to ozone

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ozone stimulus.


RNA 3' uridylation

description: The enzymatic addition of a sequence of uridylyl residues at the 3' end of an RNA molecule.


name: taurine:sodium symporter activity

description: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: taurine(out) + Na+(out) = taurine(in) + Na+(in).


neural crest formation

description: The formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation proceeds.


response to interleukin-8

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-8 stimulus.


L-glutamate biosynthetic process

description: The chemical reactions and pathways resulting in the formation of L-glutamate, the L enantiomer anion of 2-aminopentanedioic acid.


name: de novo centriole assembly via blepharoplast

description: A de novo centriole assembly process observed in multi-ciliated sperm cells of some primitive land plants, and where centrioles are formed from a blepharoplast, ultimately giving rise to multiple cilia on the sperm surface.


name: monoatomic anion:monoatomic cation symporter activity

description: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: anion(out) + cation(out) = anion(in) + cation(in).


interleukin-4 receptor activity

description: Combining with interleukin-4 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


name: farnesyl diphosphate biosynthetic process

description: The chemical reactions and pathways resulting in the formation of farnesyl diphosphate.


histone H2A deubiquitinase activity

description: A histone deubiquitinase that cleaves ubiquitin from a histone H2A protein to which it is conjugated.


double stranded viral RNA replication

description: A viral genome replication process where the template genome is double stranded RNA (dsRNA). Genomic dsRNA is first transcribed into single-stranded (ss) mRNA, which is then replicated to ds-genomic RNA.


name: symbiont-mediated suppression of host signal transduction pathway

description: A process in which a symbiont interferes with, inhibits or disrupts a host signal transduction pathway. The host is defined as the larger of the organisms involved in a symbiotic interaction.


1,4-beta-D-xylan synthase activity

description: Catalysis of the reaction: UDP-D-xylose + [(1->4)-beta-D-xylan](n) = UDP + [(1->4)-beta-D-xylan](n+1).


name: chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process

description: The elongation of chondroitin sulfate proteoglycan chains by alternate addition of N-acetylhexosamine and GlcUA residues to the GAG-protein linkage region tetrasaccharide of chondroitin sulfate.


protein O-GlcNAcylation via threonine

description: The glycosylation of a protein by addition of N-acetylglucosamine via the O3 atom of peptidyl-threonine, forming O3-N-acetylglucosamine-L-threonine.


leukotriene A4 catabolic process

description: The chemical reactions and pathways resulting in the breakdown of leukotriene A4.


cellular response to actinomycin D

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an actinomycin D stimulus.


regulation of growth

description: Any process that modulates the frequency, rate or extent of the growth of all or part of an organism so that it occurs at its proper speed, either globally or in a specific part of the organism's development.


description: The chemical reactions and pathways resulting in the breakdown of S-adenosylhomocysteine, forming homocysteine and then methionine.


plantlet formation on parent plant

description: The process in which a new plantlet develops from a meristem on the plant body. As part of this process, when the plantlet is large enough to live independently, the physical connection between the new plantlet and the main plant is severed.


phenanthrene metabolic process

description: The chemical reactions and pathways involving phenanthrene, a tricyclic aromatic hydrocarbon used in explosives and in the synthesis of dyes and drugs. Although phenanthrene is not mutagenic or carcinogenic, it has been shown to be toxic to marine diatoms, gastropods, mussels, crustaceans, and fish.


name: negative regulation of cGAS/STING signaling pathway

description: Any process that stops, prevents or reduces the frequency, rate or extent of cGAS/STING signaling pathway.


positive regulation of TORC1 signaling

description: Any process that activates or increases the frequency, rate or extent of TORC1 signaling.


description: Catalysis of the reaction: adenosine(9) in tRNA + S-adenosyl-L-methionine = H+ + N(1)-methyladenosine(9) in tRNA + S-adenosyl-L-homocysteine.


DNA replication proofreading

description: Correction of replication errors by DNA polymerase using a 3'-5' exonuclease activity.


name: symbiont-mediated suppression of host ethylene-mediated defense response

description: A process in which a symbiont inhibits or disrupts the normal execution of the ethylene-mediated defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.


apoptotic process in bone marrow cell

description: The apoptotic process in cells in the bone marrow.


name: regulation of cell migration involved in sprouting angiogenesis

description: Any process that modulates the frequency, rate or extent of cell migration involved in sprouting angiogenesis. Cell migration involved in sprouting angiogenesis is the orderly movement of endothelial cells into the extracellular matrix in order to form new blood vessels contributing to the process of sprouting angiogenesis.


inhibitory synapse assembly

description: The aggregation, arrangement and bonding together of a set of components to form an inhibitory synapse.


name: fatty acid beta-oxidation, unsaturated, odd number

description: A fatty acid beta-oxidation pathway by which fatty acids having cis-double bonds on odd-numbered carbons are degraded. In this pathway, a cis-3-enoyl-CoA is generated by the core beta-oxidation pathway, and then converted to a trans-2-enoyl-CoA, which can return to the core beta-oxidation pathway for complete degradation. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and ends when only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively).


name: extracellular matrix-dependent thymocyte migration

description: The movement of a thymocyte through distinct intrathymic niches (e.g. medulla, cortex), where it receives a unique set of developmental cues required for T-cell development, dependent on extracellular matrix components including fibronectin, collagen and laminin.


L-cysteine catabolic process to taurine

description: The chemical reactions and pathways resulting in the breakdown of L-cysteine into other compounds, including taurine.


uronic acid metabolic process

description: The chemical reactions and pathways involving uronic acid, any monocarboxylic acid formally derived by oxidizing to a carboxyl group the terminal hydroxymethylene group of either an aldose with four or more carbon atoms in the molecule, or of any glycoside derived from such an aldose.


name: positive regulation of PERK-mediated unfolded protein response

description: Any process that activates or increases the frequency, rate or extent of the PERK-mediated unfolded protein response.


name: negative regulation of blood vessel endothelial cell migration

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the migration of the endothelial cells of blood vessels.


creatine biosynthetic process

description: The chemical reactions and pathways resulting in the formation of creatine, N-[amino(imino)methyl]-N-methylglycine. Creatine is formed by a process beginning with amidino group transfer from L-arginine to glycine to form guanidinoacetate, followed by methyl group transfer from S-adenosyl-L-methionine to guanidinoacetate; it is then is phosphorylated to form a pool that stores high energy phosphate for the replenishment of ATP during periods of high, or fluctuating energy demand. In animals, most creatine is transported to and used in muscle.


protein K27-linked ubiquitination

description: A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 27 of the ubiquitin monomers, is added to a protein.


name: apoptotic process involved in heart valve morphogenesis

description: Any apoptotic process that contributes to the shaping of a heart valve.


name: protein localization to cell leading edge

description: A process in which a protein is transported to, or maintained in, a location within a cell leading edge.


diorcinol catabolic process

description: The chemical reactions and pathways resulting in the breakdown of diorcinol.


histone succinyltransferase activity

description: Catalysis of the reaction: succinyl-CoA + histone = CoA + succinyl-histone.


name: fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow cell

description: The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands, which stops, prevents, or reduces the frequency, rate or extent of the occurrence or rate of cell death by apoptotic process in the bone marrow.


name: histone H2BK5 acetyltransferase activity

description: Catalysis of the reaction: acetyl-CoA + histone H2B L-lysine (position 5) = CoA + histone H2B N6-acetyl-L-lysine (position 5).


name: 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity

description: Catalysis of the reaction: 8-oxo-7,8-dihydrodeoxyguanosine-triphosphate (8-oxo-dGTP) + H2O = 8-oxo-7,8-dihydrodeoxyguanosine phosphate (8-oxo-dGMP) + diphosphate. 8-oxo-dGTP is the oxidised form of the free guanine nucleotide and can act as a potent mutagenic substrate for DNA synthesis causing transversion mutations. 8-oxo-dGTPase hydrolyses 8-oxo-dGTP to its monophosphate form to prevent the misincorporation of 8-oxo-dGTP into cellular DNA.


ecdysone biosynthetic process

description: The chemical reactions and pathways resulting in the formation of ecdysone, (22R)-2-beta,3-beta,14,22,25-pentahydroxycholest-7-en-6-one, an ecdysteroid found in insects.


proline metabolic process

description: The chemical reactions and pathways involving proline (pyrrolidine-2-carboxylic acid), a chiral, cyclic, nonessential alpha-amino acid found in peptide linkage in proteins.


membrane protein proteolysis

description: The proteolytic cleavage of a transmembrane protein leading to the release of its intracellular or ecto-domains.


histone H3K14 deacetylase activity

description: Catalysis of the reaction: histone H3 N6-acetyl-L-lysine (position 14) + H2O = histone H3 L-lysine (position 14) + acetate. This reaction represents the removal of an acetyl group from lysine at position 14 of the histone H3 protein.


negative regulation of fever generation

description: Any process that stops, prevents, or reduces the rate or extent of fever generation.


GSI anchor biosynthetic process

description: The chemical reactions and pathways resulting in the formation of a glycosylsphingolipidinositol (GSI) anchor that attaches some membrane proteins to the lipid bilayer of the cell membrane. The sphingolipid group is linked, via the C-6 hydroxyl residue of inositol to a carbohydrate chain which is itself linked to the protein via a ethanolamine phosphate group, its amino group forming an amide linkage with the C-terminal carboxyl of the protein. Some GSI anchors have variants on this canonical linkage.


name: postsynaptic density protein 95 clustering

description: The clustering process in which postsynaptic density protein 95 (PSD-95) molecules are localized to distinct domains in the cell membrane. PSD-95 is mostly located in the post synaptic density of neurons, and is involved in anchoring synaptic proteins.


chordate embryonic development

description: The process whose specific outcome is the progression of the embryo over time, from zygote formation through a stage including a notochord and neural tube until birth or egg hatching.


carbamoyl phosphate metabolic process

description: The chemical reactions and pathways involving carbamoyl phosphate, an intermediate in the urea cycle and other nitrogen compound metabolic pathways.


hypoxanthine biosynthetic process

description: The chemical reactions and pathways resulting in the formation of hypoxanthine, 6-hydroxy purine, an intermediate in the degradation of adenylate. Its ribonucleoside is known as inosine and its ribonucleotide as inosinate.


name: planar cell polarity pathway involved in outflow tract morphogenesis

description: The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity that contributes to the shaping of the outflow tract.


name: regulation of mRNA export from nucleus in response to heat stress

description: Any process that modulates the frequency, rate or extent of mRNA export from nucleus in response to heat stress.


threonine catabolic process

description: The chemical reactions and pathways resulting in the breakdown of threonine (2-amino-3-hydroxybutyric acid), a polar, uncharged, essential amino acid found in peptide linkage in proteins.


name: positive regulation of inflammatory response to antigenic stimulus

description: Any process that activates or increases the frequency, rate, or extent of an inflammatory response to an antigenic stimulus.


trimethylenediamine metabolic process

description: The chemical reactions and pathways involving trimethylenediamine.


glucokinase activity

description: Catalysis of the reaction: ATP + D-glucose = ADP + D-glucose-6-phosphate.


name: chlorophyll a biosynthetic process via geranylgeranyl-chlorophyll a

description: The chemical reactions and pathways leading to the formation of chlorophyll a, via the intermediate geranylgeranyl-chlorophyll a.


description: Catalysis of the transfer of a glucosyl group from UDP-glucose to the 3-hydroxy group of a quercetin molecule.


interferon-omega production

description: The appearance of interferon-omega due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


name: regulation of poly(A)-specific ribonuclease activity

description: Any process that modulates the rate, frequency or extent of the catalysis of the exonucleolytic cleavage of poly(A) to 5'-AMP.


alpha-adrenergic receptor activity

description: Combining with epinephrine or norepinephrine to initiate a change in cell activity via activation of a G protein, with pharmacological characteristics of alpha-adrenergic receptors.


nucleotide receptor activity

description: Combining with a nucleotide and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. A nucleotide is a compound that consists of a nucleoside esterified with a phosphate molecule.


name: regulation of adaptive immune memory response

description: Any process that modulates the frequency, rate or extent of adaptive immune memory response.


description: The trimethylation of the N-terminal alanine of proteins to form the derivative peptidyl-N,N,N-trimethyl-L-alanine.


name: negative regulation of cAMP/PKA signal transduction

description: Any process that stops, prevents or reduces the frequency, rate or extent of cAMP/PKA signal transduction.


ecgonine methyl ester metabolic process

description: The chemical reactions and pathways involving ecgonine methyl ester.


hexose catabolic process

description: The chemical reactions and pathways resulting in the breakdown of hexose, any monosaccharide with a chain of six carbon atoms in the molecule.


name: organonitrogen compound catabolic process

description: The chemical reactions and pathways resulting in the breakdown of organonitrogen compound.


name: histone H3K4 dimethyltransferase activity

description: Catalysis of the reaction: L-lysyl4-[histone H3] + 2 S-adenosyl-L-methionine = 2 H+ + N6,N6-dimethyl-L-lysyl4-[histone H3] + 2 S-adenosyl-L-homocysteine. This reaction is the successive addition of two methyl groups to the unmethylated lysine residue at position 4 of histone H3, producing histone H3K4me2.


name: extracellularly glutamate-gated chloride channel activity

description: Enables the transmembrane transfer of a chloride ion by a channel that opens when glutamate is bound by the channel complex or one of its constituent parts on the extracellular side of the plasma membrane.


response to interleukin-3

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-3 stimulus.


name: karyogamy involved in conjugation with mutual genetic exchange

description: During sexual reproduction, the creation of a single nucleus from two nuclei as a result of fusing the nuclear envelopes that surround each nuclei. This takes place following the mutual exchange of one of the two nuclei produced by the mitosis that follows the second meiotic nuclear division. This occurs in ciliated protozoans such as Tetrahymena.


protein localization to M-band

description: Any process in which a protein is transported to, and/or maintained in, the M band. The M band is the midline of aligned thick filaments in a sarcomere.


IgG receptor activity

description: Combining with an immunoglobulin of an IgG isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


name: formation by host of specialized structure for nutrient acquisition from symbiont

description: The assembly by an organism of a cellular component or anatomical structure for the purpose of obtaining nutrients from a symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.


anaerobic electron transport chain

description: A process in which a series of electron carriers operate together to transfer electrons from donors such as NADH and FADH2 to any of several different terminal electron acceptors other than oxygen to generate a transmembrane electrochemical gradient.


peptide crotonyltransferase activity

description: Catalysis of the reaction: crotonyl-CoA + lysine in peptide = CoA + N-crotonyl-lysine-peptide.


name: indoleacetic acid amide conjugate biosynthetic process

description: The chemical reactions and pathways resulting in the formation of an indole-3-acetic acid amide conjugate, a form of indoleacetic acid covalently bound to an amino acid or polypeptide through an amide bond.


sensory perception of pain

description: The series of events required for an organism to receive a painful stimulus, convert it to a molecular signal, and recognize and characterize the signal. Pain is medically defined as the physical sensation of discomfort or distress caused by injury or illness, so can hence be described as a harmful stimulus which signals current (or impending) tissue damage. Pain may come from extremes of temperature, mechanical damage, electricity or from noxious chemical substances. This is a neurological process.


name: tryptophan catabolic process to acetyl-CoA

description: The chemical reactions and pathways resulting in the breakdown of tryptophan into other compounds, including acetyl-CoA.


histone butyryltransferase activity

description: Catalysis of the reaction: butyryl-CoA + histone = CoA + butyryl-histone.


protein-coenzyme A linkage

description: The formation of a linkage between a protein amino acid and coenzyme A.


name: transport of virus in host, cell to cell

description: The transport of a virus between adjacent cells in a multicellular organism.


name: positive regulation of lipid metabolic process

description: Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving lipids.


name: negative regulation of pteridine metabolic process

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving pteridine.


name: positive regulation of natural killer cell differentiation involved in immune response

description: Any process that activates or increases the frequency, rate or extent of natural killer cell differentiation as part of an immune response.


actinorhodin metabolic process

description: The chemical reactions and pathways involving actinorhodin.


regulation of potassium ion transport

description: Any process that modulates the frequency, rate or extent of the directed movement of potassium ions (K+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


basophil differentiation

description: The process in which a relatively unspecialized myeloid precursor cell acquires specialized features of a basophil cell.


lipid droplet fusion

description: The process by which a single lipid droplet is created from the fusion of two or more lipid droplets.


name: cellular response to macrophage colony-stimulating factor stimulus

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a macrophage colony-stimulating factor stimulus.


C4 photosynthesis

description: The combination of atmospheric CO2 with a 3-carbon molecule phosphoenol pyruvate (PEP) in the mesophyll cells to make a 4-carbon acid which is immediately converted to malic acid. The malic acid is then passed across to the bundle sheath cells where it is broken down again to pyruvic acid and CO2. The acid is passed back to the mesophyll cells to be used again, while the CO2 is fed into the reductive pentose-phosphate cycle (Calvin cycle) and converted into sugar and starch.


name: negative regulation of eosinophil differentiation

description: Any process that stops, prevents, or reduces the frequency, rate or extent of eosinophil differentiation.


name: L-lysine catabolic process to acetyl-CoA via saccharopine

description: The chemical reactions and pathways resulting in the breakdown of L-lysine into other compounds, including acetyl-CoA, via the intermediate saccharopine.


cAMP receptor activity

description: Combining with cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


name: positive regulation of CD8-positive, alpha-beta T cell extravasation

description: Any process that activates or increases the frequency, rate or extent of CD8-positive, alpha-beta T cell extravasation.


dIMP salvage

description: Any process which produces a dIMP from derivatives of it, without de novo synthesis.


name: protein localization to endoplasmic reticulum tubular network

description: A process in which a protein is transported to, or maintained in, a location within an endoplasmic reticulum tubular network.


lagging strand elongation

description: The process in which an existing DNA strand is extended in a net 3' to 5' direction by activities including the addition of nucleotides to the 3' end of the strand, complementary to an existing template, as part of DNA replication. Lagging strand DNA elongation proceeds by discontinuous synthesis of short stretches of DNA, known as Okazaki fragments, from RNA primers; these fragments are then joined by DNA ligase. Although each segment of nascent DNA is synthesized in the 5' to 3' direction, the overall direction of lagging strand synthesis is 3' to 5', mirroring the progress of the replication fork.


histone H4K deacetylase activity

description: Catalysis of the reaction: histone H4 N6-acetyl-L-lysine + H2O = histone H4 L-lysine + acetate. This reaction represents the removal of an acetyl group from a histone H4.


autophagosome-lysosome fusion

description: The process in which autophagosomes, double-membraned vesicles containing cytoplasmic material, fuse with a vacuole (yeast) or lysosome (e.g. mammals and insects). In the case of yeast, inner membrane-bounded structures (autophagic bodies) appear in the vacuole. Fusion provides an acidic environment and digestive function to the interior of the autophagosome.


name: negative regulation by symbiont of host synaptic transmission

description: Any process in which a symbiont organism decreases the frequency, rate or extent of synaptic transmission, communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse, in its host organism.


griseofulvin biosynthetic process

description: The chemical reactions and pathways resulting in the formation of griseofulvin, an important antifungal drug that has been in use for a long time for treating dermatophyte infections.


angiotensin type I receptor activity

description: An angiotensin receptor activity that acts via Gq-mediated activation of phospholipase C followed by phosphoinositide hydrolysis and Ca2+ signaling, and may act via additional signaling mechanisms.


name: isoprenoid biosynthetic process via mevalonate

description: The chemical reactions and pathways resulting in the formation of isoprenoid via mevalonate.


name: cellular response to endogenous stimulus

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus arising within the organism.


name: jasmonic acid and ethylene-dependent systemic resistance, ethylene mediated signaling pathway

description: The series of molecular signals mediated by ethylene (ethene) involved in jasmonic acid/ethylene dependent systemic resistance.


reuteran biosynthetic process

description: The chemical reactions and pathways resulting in the formation of reuteran, a soluble glucan polymer with mainly alpha-(1->4) glycosidic linkages and significant amounts of alpha-(1->6) and alpha-(1->4,6) glucosidic linkages.


name: cellular response to immobilization stress

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of being rendered immobile.


cyanide biosynthetic process

description: The chemical reactions and pathways resulting in the formation of cyanide, NC-, the anion of hydrocyanic acid. Cyanide is a potent inhibitor of respiration.


regulation of erythrocyte aggregation

description: Any process that modulates the frequency, rate, or extent of erythrocyte aggregation.


peripheral B cell deletion

description: The deletion of B cells by apoptotic process occurring as part of peripheral tolerance induction and B cell selection.


immune complex formation

description: The process that gives rise to an immune complex. Immune complexes are clusters of antibodies bound to antigen, to which complement may also be fixed, and which may precipitate or remain in solution. Examples are the clumping of cells such as bacteria or red blood cells in the presence of an antibody, precipitation of a toxin after an antibody binds to it, and clumping of viral particles as a result of antibody binding to the virus.


lsiRNA processing

description: A process leading to the generation of a functional long small interfering RNA (lsiRNA). lsiRNAs are class of siRNAs 30 to 40 nt in length. lsiRNAs are induced by pathogen infection or under specific growth conditions.


protein linear polyubiquitination

description: A protein ubiquitination process in which a linear polymer of ubiquitin, formed by the amino-terminal methionine (M1) of one ubiquitin molecule and by the carboxy-terminal glycine (G76) of the next, is added to a protein.


name: positive regulation of cell cycle G2/M phase transition

description: Any signaling pathway that activates or increases the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to M phase of the cell cycle.


name: histone H3K36 acetyltransferase activity

description: Catalysis of the reaction: acetyl-CoA + histone H3 L-lysine (position 36) = CoA + histone H3 N6-acetyl-L-lysine (position 36).


description: Catalysis of the reaction: (25S)-5beta-spirostan-3beta-ol + UDP-D-glucose = (25S)-5beta-spirostan-3beta-yl beta-D-glucoside + H+ + UDP.


galactosylceramide biosynthetic process

description: The chemical reactions and pathways resulting in the formation of galactosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of galactose by a ceramide group.


kinetochore assembly

description: The aggregation, arrangement and bonding together of a set of components to form the kinetochore, a multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules.


name: positive regulation of G2/MI transition of meiotic cell cycle

description: Any signaling pathway that activates or increases the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to MI phase of the meiotic cell cycle.


phytoene catabolic process

description: The chemical reactions and pathways resulting in the breakdown of phytoene.


coumarin biosynthetic process

description: The chemical reactions and pathways resulting in the formation of coumarins, a class of compounds derived from the phenylacrylic skeleton of cinnamic acids.


cellular response to vitamin D

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin D stimulus.


axoneme assembly

description: The assembly and organization of an axoneme, the bundle of microtubules and associated proteins that forms the core of cilia (also called flagella) in eukaryotic cells and is responsible for their movements.


name: modulation by symbiont of host cell motility

description: Modulation of host cell motility by a symbiont of that host.


prostaglandin F receptor activity

description: Combining with prostaglandin F (PGF (2-alpha)) to initiate a change in cell activity.


seminal clot liquefaction

description: The reproductive process in which coagulated semen becomes liquid following ejaculation, allowing the progressive release of motile spermatozoa.


p-cymene metabolic process

description: The chemical reactions and pathways involving p-cymene, 1-methyl-4-isopropylbenzene, one of the alkyl-substituted aromatic hydrocarbons found in volatile oils from over 100 plants.


name: modulation by host of viral RNA-binding transcription factor activity

description: A process in which a host organism modulates the frequency, rate or extent of the activity of a viral RNA-binding transcription factor.


polyol biosynthetic process

description: The chemical reactions and pathways resulting in the formation of a polyol, any alcohol containing three or more hydroxyl groups attached to saturated carbon atoms.


pyrimidine nucleobase salvage

description: Any process that generates pyrimidine nucleobases, 1,3-diazine organic nitrogenous bases, from derivatives of them without de novo synthesis.


description: The acetylation of a glutamine residue in protein to form the N5-methyl-L-glutamine derivative. The occurrence of this modification has not been confirmed. Its annotation in sequence databases is either due to the misidentification of 2-pyrrolidone-5-carboxylic acid, or to inappropriate homolog comparisons when proteolytic modification is more probable.


recombination within rDNA repeats

description: Genetic recombination within the DNA of the genes coding for ribosomal RNA.


methylglyoxal metabolic process

description: The chemical reactions and pathways involving methylglyoxal, CH3-CO-CHO, the aldehyde of pyruvic acid.


name: rRNA cytidine N-acetyltransferase activity

description: Catalysis of the reaction: acetyl-CoA + cytidine = CoA + N4-acetylcytidine. The cytidine is within the polynucleotide chain of an rRNA.


name: Gi/o-coupled serotonin receptor activity

description: Combining with serotonin and transmitting the signal across the membrane by activation of the Gi/o subunit of an associated cytoplasmic heterotrimeric G protein complex. The Gi/o subunit subsequently inhibits adenylate cyclase and results in a decrease in cyclic AMP (cAMP) levels.


name: sinapoyl spermidine:sinapoyl CoA N-acyltransferase activity

description: Catalysis of the transfer of a sinapoyl group to a nitrogen atom on a sinapoyl spermidine molecule resulting in the formation of a disinapoyl spermidine derivative.


name: positive regulation of macrophage apoptotic process

description: Any process that activates or increases the frequency, rate or extent of macrophage apoptotic process.


mRNA 3'-UTR binding

description: Binding to a 3' untranslated region of an mRNA molecule.


name: modulation of voltage-gated potassium channel activity in another organism

description: Any process in which an organism effects a change in the frequency, rate or extent of the activity of a voltage-gated potassium channel in another organism.


necroptotic signaling pathway

description: The series of molecular signals which triggers the necroptotic death of a cell. The pathway starts with reception of a signal, is characterized by activation of receptor-interacting serine/threonine-protein kinase 1 and/or 3 (RIPK1/3, also called RIP1/3), and ends when the execution phase of necroptosis is triggered.


RNA replication

description: The cellular metabolic process in which a cell duplicates one or more molecules of RNA.


name: spliceosome-depend formation of circular RNA

description: Formation of circular RNAs (circRNAs) by back-splicing circularization of pre-mRNAs in a spliceosome-dependent process.


name: cellular response to Thyroglobulin triiodothyronine

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a Thyroglobulin triiodothyronine stimulus.


name: positive regulation of serotonin biosynthetic process

description: Any process that activates or increases the frequency, rate or extent of serotonin biosynthetic process.


ergosterol metabolic process

description: The chemical reactions and pathways involving ergosterol, (22E)-ergosta-5,7,22-trien-3-beta-ol, a sterol found in ergot, yeast and moulds. It is the most important of the D provitamins and is converted to vitamin D2 on irradiation with UV light.


biofilm matrix organization

description: A process that results in the assembly, arrangement of constituent parts, or disassembly of a biofilm matrix.


modulation by virus of host autophagy

description: Any process in which a virus effect a change in the frequency, rate or extent of autophagy in the host.


name: negative regulation of macromolecule metabolic process

description: Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.


response to hormone

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hormone stimulus.


description: Catalysis of the reaction: UDP-N-acetyl-D-galactosamine + polypeptide = UDP + N-acetyl-D-galactosaminyl-polypeptide. This reaction is the modification of serine or threonine residues in polypeptide chains by the transfer of a N-acetylgalactose from UDP-N-acetylgalactose to the hydroxyl group of the amino acid; it is the first step in O-glycan biosynthesis.


name: positive regulation of inflammasome-mediated signaling pathway

description: Any process that activates or increases the frequency, rate or extent of an inflammasome-mediated signaling pathway.


name: positive regulation of activation-induced cell death of T cells

description: Any process that activates or increases the frequency, rate or extent of activation-induced cell death of T cells.


name: sorbitol transmembrane transporter activity

description: Enables the transfer of sorbitol from one side of a membrane to the other. Sorbitol, also known as glucitol, is the hexitol derived by the reduction of the aldehyde group of glucose.


description: The chemical reactions and pathways resulting in the formation of S-adenosylmethionine, S-(5'-adenosyl)-L-methionine, an important intermediate in one-carbon metabolism.


name: positive regulation of coenzyme F420-dependent bicyclic nitroimidazole catabolic process

description: Any process that activates or increases the frequency, rate or extent of coenzyme F420-dependent bicyclic nitroimidazole catabolic process.


O-glycan processing, core 6

description: The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form the core 6 O-glycan structure, GlcNAc-beta-(1->6)-GalNAc.


fructoselysine metabolic process

description: The chemical reactions and pathways involving fructoselysine, a fructose molecule containing a lysine group in place of a hydroxyl group.


name: dehydrodolichyl diphosphate synthase activity

description: Catalysis of the condensation of isopentenyl diphosphate and farnesyl diphosphate in the cis-configuration to form dehydrodolichyl diphosphate.


name: negative regulation of anthocyanin biosynthetic process

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of anthocyanins.


name: cellular response to inositol starvation

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of inositol.


peptidyl-cysteine sulfation

description: The sulfation of peptidyl-cysteine to form S-sulfo-L-cysteine.


name: amino acid catabolic process via Ehrlich pathway

description: The chemical reactions and pathways involving the catabolism of amino acids to produce alcohols or carboxylic acids containing one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of alcohols, often collectively referred to as fusel alcohols. Depending on the redox state of the cells, carboxylic acid derivatives, sometimes referred to as fusel acids, may be produced instead of alcohols.


6-hydroxycineole metabolic process

description: The chemical reactions and pathways involving 6-hydroxycineole (6-hydroxy-1,8-epoxy-p-menthane), a hydrocarbon with the formula C10H18O2.


extracellular matrix assembly

description: The aggregation, arrangement and bonding together of the extracellular matrix.


name: negative regulation of macrophage colony-stimulating factor signaling pathway

description: Any process that stops, prevents or reduces the frequency, rate or extent of macrophage colony-stimulating factor signaling pathway.


name: myo-inositol hexakisphosphate metabolic process

description: The chemical reactions and pathways involving phytic acid, myo-inositol hexakisphosphate, a regulator of intracellular signaling, a highly abundant animal anti-nutrient and a phosphate and mineral storage compound in plant seeds.


name: positive regulation of ephrin receptor signaling pathway

description: Any process that activates or increases the frequency, rate or extent of ephrin receptor signaling pathway.


methanol biosynthetic process

description: The chemical reactions and pathways resulting in the formation of methanol, CH3-OH, a colorless, flammable, mobile, poisonous liquid, widely used as a solvent.


centriole assembly

description: A cellular process that results in the assembly of one or more centrioles.


description: Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + beta-D-mannosyl-R = UDP + 4-(N-acetyl-beta-D-glucosaminyl)-beta-D-mannosyl-R.


description: Catalysis of the reaction: (DNA)-3'-diphospho-5'-guanosine + H2O = (DNA)-3'-phosphate + GMP.


actin filament-based process

description: Any cellular process that depends upon or alters the actin cytoskeleton, that part of the cytoskeleton comprising actin filaments and their associated proteins.


response to interleukin-11

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-11 stimulus.


name: nucleoside diphosphate phosphatase activity

description: Catalysis of the reaction: a nucleoside diphosphate + H2O = a nucleoside monophosphate + phosphate.


eye pigment granule organization

description: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of intracellular pigment storage granules in the eye.


description: The chemical reactions and pathways resulting in the breakdown of sphinganine-1-phosphate, the phosphorylated derivative of D-erythro-2-amino-1,3-octadecanediol.


name: inhibitory killer cell immunoglobulin-like receptor signaling pathway

description: The series of molecular signals initiated by an extracellular ligand binding to a inhibitory killer cell immunoglobulin-like receptor capable of inhibiting an immune effector process contributing to an immune response.


toxin metabolic process

description: The chemical reactions and pathways involving a toxin, a poisonous compound (typically a protein) that is produced by cells or organisms and that can cause disease when introduced into the body or tissues of an organism.


interleukin-26 receptor activity

description: Combining with interleukin-26 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


name: positive regulation of leaflet formation by auxin mediated signaling pathway

description: Any process that increases the frequency, rate or extent of leaflet formation as a result of the series of molecular signals generated in response to detection of auxin.


chanoclavine-I metabolic process

description: The chemical reactions and pathways involving chanoclavine-I.


name: symbiont-mediated evasion of recognition by host antimicrobial peptide

description: A process by which a symbiont avoids the effects of recognition by a host  antimicrobial peptide by altering molecules on the symbiont surface. The host is defined as the larger of the organisms involved in a symbiotic interaction.


name: protein localization to photoreceptor outer segment

description: A process in which a protein is transported to, or maintained in, a location within a photoreceptor outer segment.


name: negative regulation of CD40 signaling pathway

description: Any process that stops, prevents or reduces the frequency, rate or extent of signaling via the CD40 signaling pathway.


Golgi reassembly

description: The reformation of the Golgi following its breakdown and partitioning contributing to Golgi inheritance.


arginine catabolic process to spermine

description: The chemical reactions and pathways resulting in the breakdown of arginine into other compounds, including spermine.


L-asparagine biosynthetic process

description: The chemical reactions and pathways resulting in the formation of asparagine, (2S)-2-amino-3-carbamoylpropanoic acid.


membrane protein ectodomain proteolysis

description: The proteolytic cleavage of transmembrane proteins and release of their ectodomain (extracellular domain).


ITP catabolic process

description: The chemical reactions and pathways resulting in the breakdown of ITP, inosine (5'-)triphosphate.


erythropoietin receptor activity

description: Combining with erythropoietin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


name: viral mRNA export from host cell nucleus

description: The directed movement of intronless viral mRNA from the host nucleus to the cytoplasm for translation.


2-deoxystreptamine biosynthetic process

description: The chemical reactions and pathways resulting in the formation of 2-deoxystreptamine.


C-terminal protein deglutamylation

description: The removal of a C-terminal, gene-encoded glutamate residue from a protein.


AAU codon-amino acid adaptor activity

description: A triplet codon-amino acid adaptor activity that recognizes an AAU codon.


thymocyte migration

description: The movement of a thymocyte through distinct intrathymic niches (e.g. medulla, cortex), where it receives a unique set of developmental cues required for T-cell development.


cellular response to dextromethorphan

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dextromethorphan stimulus.


name: positive regulation of mitochondrial membrane permeability involved in apoptotic process

description: Any positive regulation of mitochondrial membrane permeability that is involved in apoptotic process.


description: Catalysis of the reaction: N-acetylneuraminyl-2,3-alpha-D-galactosyl-1,4-beta-D-glucosylceramide + UDP-N-acetylgalactosamine = N-acetyl-beta-D-galactosaminyl-1,4-(N-acetyl-alpha-neuraminyl-2,3)-beta-D-galactosyl-1,4-beta-D-glucosylceramide + UDP.


sperm DNA condensation

description: The progressive compaction of the spermatid chromatin so that it reaches a level of condensation that is not compatible with nuclear activities such as transcription or DNA replication.


name: protoporphyrinogen IX biosynthetic process from glutamate

description: The chemical reactions and pathways resulting in the formation of protoporphyrinogen IX from other compounds, including glutamate.


virion maturation

description: Maturation of a virion after separation from the host cell. Not all viruses mature after separation. In those that do, maturation typically involves rearangement and/or cleavage of viral proteins, resulting in the virion becoming competent for reinfection.


name: negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

description: Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator.


peptidyl-glutamic acid methylation

description: The addition of a methyl group to a glutamic acid residue in a protein.


name: P450-containing electron transport chain

description: A electron transport chain in which one or more electron carriers operate to transfer electrons from donors to a cytochrome P450 protein or domain. Electron carriers operating in this chain include FAD-containing flavoproteins or domains, FMN domains, ferredoxins and cytochrome b5. The reduced cytochrome P450 functions as the terminal oxidase and participates in a wide range of biochemical pathways.


name: benzoate transmembrane transporter activity

description: Enables the directed movement of benzoate, the anion of benzoic acid (benzenecarboxylic acid) from one side of a membrane to the other.


plasma membrane raft distribution

description: The process that establishes the spatial arrangement of membrane rafts within a plasma membrane.


name: pyridine-containing compound catabolic process

description: The chemical reactions and pathways resulting in the breakdown of a pyridine-containing compound, i.e. any compound that contains pyridine or a formal derivative thereof.


name: iron incorporation into metallo-sulfur cluster

description: The incorporation of iron into a metallo-sulfur cluster.


name: protein serine/threonine kinase activity

description: Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.


olefin metabolic process

description: The chemical reactions and pathways involving olefin.


apocarotenoid biosynthetic process

description: The chemical reactions and pathways resulting in the formation of apocarotenoids by the oxidative cleavage of carotenoids. Many apocarotenoids are biologically important e.g. retinal and abscisic acid.


dimethylsilanediol metabolic process

description: The chemical reactions and pathways involving dimethylsilanediol, the smallest member of the dialkylsilanediols. Dimethylsilanediol is the monomer of polydimethylsiloxane, a compound which can be found in a wide range of industrial and consumer products.


rolling circle DNA replication

description: A DNA-dependent DNA replication process in which a single-stranded DNA molecule is synthesized from a circular duplex template. Replication typically does not cease when one circumference has been replicated, but continues around the circumference several more times, producing a long single strand comprising multimers of the replicon.


name: regulation of lateral motor column neuron migration

description: Any process that modulates the frequency, rate or extent of lateral motor column neuron migration.


tridecane metabolic process

description: The chemical reactions and pathways involving tridecane.


(+)-camphor metabolic process

description: The chemical reactions and pathways involving (+)-camphor, a bicyclic monoterpene ketone which is one of the major components in the leaves of common sage. Camphor exists in two enantiomers, but the (+)-isomer is more widely distributed.


name: iron incorporation into iron-sulfur cluster via tris-L-cysteinyl L-cysteine persulfido bis-L-glutamato L-histidino nickel triiron disulfide trioxide

description: The incorporation of iron into a 3Fe-2S cluster via tris-L-cysteinyl L-cysteine persulfido bis-L-glutamato L-histidino nickel triiron disulfide trioxide.


name: regulation of emodin biosynthetic process

description: Any process that modulates the frequency, rate or extent of emodin biosynthetic process.


description: Catalysis of the reaction: a cytidine in tRNA + S-adenosyl-L-methionine = an N3-methylcytidine in tRNA + H+ + S-adenosyl-L-homocysteine.


cocaine catabolic process

description: The chemical reactions and pathways resulting in the breakdown of cocaine, an alkaloid obtained from the dried leaves of the shrub Erythroxylon coca. It is a cerebral stimulant and narcotic.


galactarate catabolic process

description: The chemical reactions and pathways resulting in the breakdown of galactarate, the anion of galactaric acid.


name: response to mitotic cell cycle spindle assembly checkpoint signaling

description: A process that occurs in response to signals generated as a result of mitotic cell cycle spindle assembly checkpoint signaling.


cellular response to sucrose stimulus

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sucrose stimulus.


name: anatomical structure formation involved in morphogenesis

description: The developmental process pertaining to the initial formation of an anatomical structure from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.


name: negative regulation of planar cell polarity pathway involved in neural tube closure

description: Any process that stops, prevents, or reduces the frequency, rate or extent of planar cell polarity pathway involved in neural tube closure.


selenoneine metabolic process

description: The chemical reactions and pathways involving selenoneine.


response to lead ion

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lead ion stimulus.


name: proteinogenic amino acid metabolic process

description: The chemical reactions and pathways involving any amino acid that is incorporated into protein naturally by ribosomal translation of mRNA, and that has a specific codon for translation from mRNA to protein.


cytidine biosynthetic process

description: The chemical reactions and pathways resulting in the formation of cytidine, cytosine riboside, a widely distributed nucleoside.


heptose 7-phosphate kinase activity

description: Catalysis of the reaction: D-alpha,beta-D-heptose-7-phosphate + ATP = D-beta-D-heptose-1,7-bisphosphate + ADP.


name: diphosphoinositol polyphosphate catabolic process

description: The chemical reactions and pathways resulting in the breakdown of a diphosphoinositol polyphosphate, 1,2,3,4,5,6-cyclohexanehexol with one or more diphosphate groups and multiple monophosphate groups attached.


name: dopamine:sodium symporter activity

description: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: dopamine(out) + Na+(out) + Cl-(out)= dopamine(in) + Na+(in) + Cl-(in).


name: negative regulation of type I interferon-mediated signaling pathway

description: Any process that decreases the rate, frequency or extent of a type I interferon-mediated signaling pathway.


name: hydrolase activity, acting on glycosyl bonds

description: Catalysis of the hydrolysis of any glycosyl bond.


regulation of sexual sporulation

description: Any process that modulates the frequency, rate or extent of spore formation from the products of meiosis. An example of this is found in Saccharomyces cerevisiae.


protein localization to cell cortex

description: A process in which a protein is transported to, or maintained in, the cell cortex.


peptide antibiotic metabolic process

description: The chemical reactions and pathways involving peptides with antibiotic activity.


CGC codon-amino acid adaptor activity

description: A triplet codon-amino acid adaptor activity that recognizes a CGC codon.


name: histone H2AK9 acetyltransferase activity

description: Catalysis of the reaction: acetyl-CoA + histone H2A L-lysine (position 9) = CoA + histone H2A N6-acetyl-L-lysine (position 9).


name: mRNA N1-methyladenosine dioxygenase activity

description: Catalysis of the oxidative demethylation of N1-methyladenosine RNA, with concomitant decarboxylation of 2-oxoglutarate and releases oxidized methyl group on N1-methyladenosine as formaldehyde.


name: erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process

description: The chemical reactions and pathways involving erythrose 4-phosphate/phosphoenolpyruvate family amino acid.


name: 5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate metabolic process

description: The chemical reactions and pathways involving 5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate.


name: positive regulation of macrophage differentiation

description: Any process that activates or increases the frequency, rate or extent of macrophage differentiation.


name: positive regulation of G1/S transition of mitotic cell cycle

description: Any signaling pathway that increases or activates a cell cycle cyclin-dependent protein kinase to modulate the switch from G1 phase to S phase of the mitotic cell cycle.


t-circle formation

description: A telomere maintenance process that results in the formation of a telomeric circle, or t-circle. A t-circle is an extrachromosomal duplex or single-stranded circular DNA molecule composed of t-arrays. T-circles are involved in the control of telomere length via alternative-lengthening of telomeres (ALT) pathway and telomere rapid deletion (TRD).


isogloboside biosynthetic process

description: The chemical reactions and pathways resulting in the formation of a lactosyl-ceramide derivative in which a galactose is linked to the galactose via an alpha 1,3 linkage (vs alpha 1,4 for globosides).


name: RNA polymerase II C-terminal domain S5 O-GlcNAc transferase activity

description: Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + RNA polymerase II large subunit CTD heptapeptide repeat (YSPTSPS) = UDP + RNA polymerase II large subunit CTD heptapeptide repeat 3-O-(N-acetyl-D-glucosaminyl)-L-serine (position 5).


name: positive regulation of initiation of premeiotic DNA replication

description: Any process that activates or increases the frequency, rate or extent of initiation of premeiotic DNA replication.


tetrahydrofuran catabolic process

description: The chemical reactions and pathways resulting in the breakdown of tetrahydrofuran, a cyclic 4 carbon ether. It is one of the most polar ethers and is a widely used solvent for polar reagents. Since THF is very soluble in water and has a relatively low boiling point, significant amounts are often released into the environment, causing contamination problems.


name: N-terminal protein amino acid acetylation

description: The acetylation of the N-terminal amino acid of proteins.


L-sorbose metabolic process

description: The chemical reactions and pathways involving sorbose, the L-enantiomer of the ketohexose xylo-2-hexulose. L-sorbose is formed by bacterial oxidation of sorbitol.


cellular response to undecane

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an undecane stimulus.


cellular response to angiotensin

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an angiotensin stimulus. Angiotensin is any of three physiologically active peptides (angiotensin II, III, or IV) processed from angiotensinogen.


testicular fusome organization

description: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the fusome of testicular cells, an organelle derived from the spectrosome.


name: G protein-coupled neurotransmitter receptor activity

description: Combining with a neurotransmitter and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.


name: cellular response to gonadotropin stimulus

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gonadotropin stimulus.


FMN metabolic process

description: The chemical reactions and pathways involving FMN, riboflavin 5'-(dihydrogen phosphate), a coenzyme for a number of oxidative enzymes including NADH dehydrogenase.


cellular response to diphenidol

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diphenidol stimulus.


paracrine signaling

description: The transfer of information from one cell to another, where the signal travels from the signal-producing cell to the receiving cell by passive diffusion or bulk flow in intercellular fluid. The signaling cell and the receiving cell are usually in the vicinity of each other.


name: negative regulation of intracellular signal transduction

description: Any process that stops, prevents or reduces the frequency, rate or extent of intracellular signal transduction.


name: macrophage inflammatory protein-1 alpha production

description: The appearance of macrophage inflammatory protein 1 alpha due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


name: cellular response to increased oxygen levels

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting an increase in the level of oxygen.


spermatid nucleus elongation

description: The change in shape of the spermatid nucleus from a spherical structure to an elongated organelle, during the latter part of spermatid differentiation.


name: symbiont genome entry into host cell via pore formation in plasma membrane

description: Entry of a symbiont's genome into a host cell by a pore formed by the symbiont in the host cell. Examples of this process include injection by a non-enveloped virus of the viral genome into the host cytoplasm, usually mediated by a viral pore-forming peptide associated with the viral capsid or bacteriophage tail.


thrombopoietin receptor activity

description: Combining with the glycoprotein thrombopoietin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


description: The chemical reactions and pathways involving 7,8-didemethyl-8-hydroxy-5-deazariboflavin.


circadian behavior

description: The specific behavior of an organism that recurs with a regularity of approximately 24 hours.


name: symbiont-mediated perturbation of host transcription

description: A process in which a symbiont alters or subverts transcription in its host. The host is defined as the larger of the organisms involved in a symbiotic interaction.


apocarotenoid metabolic process

description: The chemical reactions and pathways involving apocarotenoids, a class of compounds derived from the oxidative cleavage of carotenoids, many of which are biologically important e.g. retinal and abscisic acid.


bombesin receptor signaling pathway

description: A G protein-coupled receptor signaling pathway initiated by a bombesin binding to its receptor, and ending with the regulation of a downstream cellular process, e.g. transcription.


thiamine diphosphate dephosphorylation

description: The removal of one or more phosphate groups from thiamine diphosphate, a derivative of thiamine (vitamin B1) which acts as a coenzyme in a range of processes including the Krebs cycle.


description: Catalysis of the reaction: cytidine(34) in tRNA + S-adenosyl-L-methionine = 2'-O-methylcytidine(34) in tRNA + H+ + S-adenosyl-L-homocysteine.


tetrahydrofolate metabolic process

description: The chemical reactions and pathways involving tetrahydrofolate, 5,6,7,8-tetrahydrofolic acid, a folate derivative bearing additional hydrogens on the pterin group.


name: negative regulation of toll-like receptor 15 signaling pathway

description: Any process that stops, prevents or reduces the frequency, rate or extent of toll-like receptor 15 signaling pathway.


name: regulation of carbohydrate metabolic process

description: Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving carbohydrates.


description: The chemical reactions and pathways involving CMP-N-acetylneuraminate, a substance composed of 5-(acetylamino)-3,5-dideoxy-D-glycero-D-galacto-non-3-ulosonic acid in glycosidic linkage with cytidine monophosphate.


T cell mediated cytotoxicity

description: The directed killing of a target cell by a T cell through the release of granules containing cytotoxic mediators or through the engagement of death receptors.


name: negative regulation of T cell apoptotic process

description: Any process that stops, prevents, or reduces the frequency, rate or extent of T cell death by apoptotic process.


name: negative regulation of Fas signaling pathway

description: Any process that stops, prevents or reduces the frequency, rate or extent of Fas signaling pathway.


name: mating-type P-factor pheromone receptor activity

description: Combining with the mating-type peptide pheromone P-factor and transmitting the signal across the membrane to initiate a change in cell activity. P-factor is a polypeptide of 23 residues, with the sequence Thr-Tyr-Ala-Asp-Phe-Leu-Arg-Ala-Tyr-Gln-Ser-Trp-Asn-Thr-Phe-Val-Asn-Pro-Asp-Arg-Pro-Asn-Leu, and is a peptide pheromone released by Schizosaccharomyces pombe cells of the cellular mating type Plus.


3-chlorocatechol catabolic process

description: The chemical reactions and pathways resulting in the breakdown of 3-chlorocatechol.


name: regulation of apoptosis involved in tissue homeostasis

description: Any process that modulates the occurrence or rate of cell death by apoptosis that results in the maintenance of the steady-state number of cells within a tissue.


name: positive regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway

description: Any process that activates or increases the frequency, rate or extent of adenylate cyclase-inhibiting dopamine receptor signaling pathway.


name: copper incorporation into copper-sulfur cluster

description: The incorporation of copper into a copper-sulfur cluster.


xylan biosynthetic process

description: The chemical reactions and pathways resulting in the formation of xylan, a polymer containing a beta-1,4-linked D-xylose backbone.


CAA codon-amino acid adaptor activity

description: A triplet codon-amino acid adaptor activity that recognizes a CAA codon.


name: vascular endothelial cell response to pulsatile fluid shear stress

description: Any response to pulsatile fluid shear stress that occurs in a vascular endothelial cell.


name: circadian regulation of systemic arterial blood pressure

description: Any process in which an organism modulates its blood pressure at different values with a regularity of approximately 24 hours.


fibroblast apoptotic process

description: Any apoptotic process in a fibroblast, a connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules.


GDP-mannose hydrolase activity

description: Catalysis of the reaction: GDP-mannose + H2O = GMP + mannose-1-phosphate.


name: symbiont-mediated suppression of host RNAi-mediated antiviral immune response

description: A process by which a symbiont inhibits or disrupts the host's RNAi-mediated antiviral immune response. The host is defined as the larger of the organisms involved in a symbiotic interaction.


cellular response to iron ion

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron ion stimulus.


name: 2-dehydro-3-deoxy-D-gluconic acid metabolic process

description: The chemical reactions and pathways involving 2-dehydro-3-deoxy-D-gluconic acid.


name: negative regulation of ecdysone receptor signaling pathway

description: Any process that stops, prevents, or reduces the frequency, rate or extent of any ecdysone receptor signaling pathway.


name: positive regulation of xylose catabolic process to ethanol

description: Any process that activates or increases the frequency, rate or extent of xylose catabolic process to ethanol.


regulation of DNA repair

description: Any process that modulates the frequency, rate or extent of DNA repair.


ethanolamine catabolic process

description: The chemical reactions and pathways resulting in the breakdown of ethanolamine (2-aminoethanol), an important water-soluble base of phospholipid (phosphatidylethanolamine).


name: positive regulation of monocyte extravasation

description: Any process that activates or increases the frequency, rate or extent of monocyte extravasation.


priRNA 3'-end processing

description: The process of forming the mature 3' end of a priRNA molecule.


P granule organization

description: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of polar granules, cytoplasmic, non-membranous RNA/protein complex aggregates in the primordial germ cells of many higher eukaryotes.


neuromedin K receptor activity

description: Combining with neuromedin K, the peptide Asp-Met-His-Asp-Phe-Phe-Val-Gly-Leu-Met to initiate a change in cell activity.


dAMP catabolic process

description: The chemical reactions and pathways resulting in the breakdown of dAMP, deoxyadenosine monophosphate (2'-deoxyadenosine 5'-phosphate).


name: suppression by virus of host cell wall biogenesis

description: Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of cell wall biogenesis in the host organism. Cell wall biogenesis includes the biosynthesis of constituent macromolecules, and the assembly and arrangement of these constituent parts.


name: histone H3K72 acetyltransferase activity

description: Catalysis of the reaction: acetyl-CoA + histone H3 L-lysine (position 72) = CoA + histone H3 N6-acetyl-L-lysine (position 72).


name: tRNA (cytidine) methyltransferase activity

description: Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing methylcytosine.


phragmoplast microtubule organization

description: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures formed of microtubules and associated proteins in phragmoplast, a plant cell specific structure that forms during late cytokinesis. Phragmoplast serves as a scaffold for cell plate assembly and subsequent formation of a new cell wall separating the two daughter cells.


name: endodermal-mesodermal cell signaling involved in heart induction

description: Any process that mediates the transfer of information from endodermal cells to mesodermal cells that contributes to heart induction.


ent-kaurene metabolic process

description: The chemical reactions and pathways involving ent-kaur-16-ene. Ent-kaurene is a tetracyclic diterpenoid that is a precursor of several plant isoprenoids, including gibberellins.


CDP-glycerol diphosphatase activity

description: Catalysis of the reaction: CDP-glycerol + H2O = sn-glycerol 3-phosphate + CMP + 2 H+.


name: glial cell-derived neurotrophic factor receptor activity

description: Combining with glial cell line-derived neurotrophic factor and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


activin receptor activity

description: Combining with activin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. Activin is one of two gonadal glycoproteins related to transforming growth factor beta.


histone H3K4 acetyltransferase activity

description: Catalysis of the reaction: acetyl-CoA + histone H3 L-lysine (position 4) = CoA + histone H3 N6-acetyl-L-lysine (position 4).


asperthecin metabolic process

description: The chemical reactions and pathways involving asperthecin, an anthraquinone pigment obtained from the mould Aspergillus nidulans.


nuclear speck organization

description: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of nuclear specks, a class of nuclear body in which splicing factors are localized.


hexokinase activity

description: Catalysis of the reaction: ATP + D-hexose = ADP + D-hexose 6-phosphate.


nicotinate metabolic process

description: The chemical reactions and pathways involving nicotinate.


name: positive regulation of toll-like receptor 8 signaling pathway

description: Any process that activates or increases the frequency, rate, or extent of toll-like receptor 8 signaling pathway.


name: envenomation resulting in negative regulation of voltage-gated potassium channel activity in another organism

description: A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant negative regulation of the activity of a voltage-gated potassium channel in the bitten/stung organism.


name: low-affinity tryptophan transmembrane transporter activity

description: Catalysis of the low-affinity transfer of L-tryptophan from one side of a membrane to the other. Tryptophan is 2-amino-3-(1H-indol-3-yl)propanoic acid. In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations.


mannoprotein metabolic process

description: The chemical reactions and pathways involving a mannoprotein, a protein that contains covalently bound mannose residues.


name: regulation of single-strand break repair via homologous recombination

description: Any process that modulates the frequency, rate or extent of single-strand break repair via homologous recombination.


name: extrinsic apoptotic signaling pathway via death domain receptors

description: The series of molecular signals in which a signal is conveyed from the cell surface to trigger the apoptotic death of a cell. The pathway starts with a ligand binding to a death domain receptor on the cell surface, and ends when the execution phase of apoptosis is triggered.


ferulate metabolic process

description: The chemical reactions and pathways involving ferulate, (2E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoate.


alginic acid metabolic process

description: The chemical reactions and pathways involving alginic acid, a hydrophilic polysaccharide occurring in, for example, the cell walls of brown algae (brown seaweeds).


nitrobenzene biosynthetic process

description: The chemical reactions and pathways resulting in the formation of nitrobenzene.


response to platinum ion

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a platinum stimulus.


mRNA alternative polyadenylation

description: The process of generating multiple mRNA molecules with variable 3'-end length formation from a given pre-mRNA by differential use of cleavage and polyadenylation signals (pA signals).


heme O metabolic process

description: The chemical reactions and pathways involving heme O, a derivative of heme containing a 17-carbon hydroxyethylfarnesyl side chain at position 8 of the tetrapyrrole macrocycle.


name: response to DNA integrity checkpoint signaling

description: A process that occurs in response to signals generated as a result of DNA integrity checkpoint signaling.


purine nucleotide binding

description: Binding to a purine nucleotide, a compound consisting of a purine nucleoside esterified with (ortho)phosphate.


response to streptomycin

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a streptomycin stimulus. Streptomycin is a commonly used antibiotic in cell culture media which acts only on prokaryotes and blocks transition from initiation complex to chain elongating ribosome.


name: transferase activity, transferring phosphorus-containing groups

description: Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to another (acceptor).


description: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: neurotransmitter(out) + Na+(out) = neurotransmitter(in) + Na+(in).


cotyledon development

description: The process whose specific outcome is the progression of the cotyledon over time, from its formation to the mature structure. The cotyledon is the modified leaf (seed leaf), found as part of the embryo in plant seeds. It is involved in either storage or absorption of food reserves. Dicotyledonous seeds contain two cotyledons, while monocotyledonous seeds contain only one. The cotyledons may appear above ground and show photosynthetic activity in the seedling.


amino acid activation

description: The modification of an amino acid to an active form, for incorporation into a peptide, protein or other macromolecule.


name: envenomation resulting in modulation of sensory perception of pain in another organism

description: A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the modulation of the sensory perception of pain in the bitten organism.


carotene metabolic process

description: The chemical reactions and pathways involving carotenes, hydrocarbon carotenoids.


regulation of response to stress

description: Any process that modulates the frequency, rate or extent of a response to stress. Response to stress is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).


name: protein-keratan sulfate linkage via keratan sulfate D-glucuronyl-D-galactosyl-D-galactosyl-D-xylosyl-L-threonine

description: Keratan sulfate components are covalently linked to a core glycoprotein via O-glycosidic linkages between xylose and threonine residues.


dCMP metabolic process

description: The chemical reactions and pathways involving dCMP, deoxycytidine monophosphate.


name: chemokine (C-C motif) ligand 2 signaling pathway

description: The series of molecular signals initiated by the binding of the C-C chemokine CCL2 to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.


protein dehydration

description: The removal of a water group from a protein amino acid.