A sialotetraosylceramide consisting of a branched hexasaccharide made up from two sialyl residues, two galactose residues, one N-acetylgalactosamine residue and a glucose residue at the reducing end attached to the ceramide portion via a beta-linkage.


GlyTouCan G00194GV

A composition-only glycan consisting of one acetaminohexosyl group and one 6-deoxyhexosyl group (identities and connectivity unknown). Composition: HexNAc1 dHex1.


A glycophytoceramide having a 4-O-(4-methylbenzyl)-alpha-D-galactosyl residue at the O-1 position and a hexacosanoyl group attached to the nitrogen. One of a series of an extensive set of 4"-O-alkylated alpha-GalCer analogues evaluated (PMID:30556652) as invariant natural killer T-cell (iNKT) antigens.


alpha-methyl-L-phenylalanine

An L-phenylalanine derivative that consists of L-phenylalanine bearing an additional methyl substituent at position 2.


A synthetic tetrapeptide comprising Ac-Cha, Cpg, Tic and Met-NH2 residues coupled in sequence.


An eight-membered homodetic cyclic peptide comprising the sequence L-leucine, L-serine, L-alpha-glutamic acid, L-threonine, O-sulfo-L-tyrosine, L-threonine, L-lysine, D-leucine.


A fifteen-membered glycopeptide comprising glycyl, homoleucyl, alanyl, glycyl, 4-fluorophenylalanyl, (5R)-5-(beta-D-galactopyranosyloxy)lysyl, glycyl. alpha-glutamyl, glutaminyl, glycyl, prolyl, lysyl, glycyl, alpha-glutamyl and threonine residues coupled in sequence.


name: (2S, 3S, 4R)-2-[(2'R)-2'-hydroxypentacosanoylamino]-1, 3, 4-octadecanetriol


An N-(1-phenylethyl)acetamide that has S configuration.


An amino disaccharide consisting of 2-acetamido-2-deoxy-beta-D-galactopyranose and 2-acetamido-2-deoxy-alpha-D-glucopyranose residues joined in sequence by a (1->4) glycosidic bond.


Major microspecies at pH 7.3.


2-methylaminoethylphosphonic acid

A phosphonic acid having a 2-methylaminoethyl group attached to the phosphorus.


Ala-Leu-Thr-Pro

A tetrapeptide composed of L-alanine, L-leucine, L-threonine, and L-proline units joined in sequence.


toluene 2,6-diisocyanate

A toluene meta-diisocyanate in which the isocyanato groups are at positions 2 and 6 relative to the methyl group on the benzene ring.


An amino trisaccharide consisting of alpha-D-galactosyl, N-acetyl-beta-D-glucosaminyl and alpha-D-mannose residues joined in sequence by (1->3) and (1->2) glycosidic bonds.


isoglobotetraosyl ceramide

A glycotetraosylceramide compound having an isoglobotetraosyl moiety attached to the primary hydroxy group of the ceramide.


1-nitroguanidine derivative

Any nitroguanidine derivative resulting from the replacement of one or more hydrogens of 1-nitroguanidine by an organyl group.


butylphosphonic acid

A member of the class of phosphonic acids that is phosphonic acid having a butyl group attached to the phosphorous atom.


A secondary carboxamide resulting from the formal condensation of the carboxy group of  3-cyclopentylpropionic acid with the amino group of [biphenyl]-2-amine.


An artificial glycosphingolipid composed of the ceramide mimetic C12L (CHEBI:190285) bound to a beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-[alpha-L-Fuc-(1->6)]-D-GlcNAc oligosaccharide via a beta-linkage.


A glycosylceramide obtained by formal condensation of the carboxy group of docosanoic acid with the amino group of 1-(2',3',4',6'-tetraacetylbeta-D-galactosyl)-3-acetylsphingosine.


A beta-D-glucosyl-(1<->1')-N-acylsphinganine in which the acyl group specified is tetracosanoyl.


name: 3-[[oxo(2-quinoxalinyl)methyl]amino]benzoic acid ethyl ester


glucagon

A 29-amino acid peptide hormone consisting of His, Ser, Gln, Gly, Thr, Phe, Thr, Ser, Asp, Tyr, Ser, Lys, Tyr, Leu, Asp, Ser, Arg, Arg, Ala, Gln, Asp, Phe, Val, Gln, Trp, Leu, Met, Asn and Thr residues joined in sequence.


A ten-membered oligopeptide comprising D-arginyl, L-arginyl, L-prolyl, (4R)-4-hydroxy-L-prolyl, glycyl, L-phenylalanyl, L-seryl, D-phenylalanyl, L-phenylalanyl and L-arginine residues joined in sequence.


aldoxime

Oximes of aldehydes RCH=NOH.


ganglioside GM2 (20:0)

A sialotriaosylceramide that is N-acetyl-beta-D-galactosaminyl-(1->4)-alpha-N-acetylneuraminosyl-(2->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-N-acylsphingosine in which the acyl group on the sphingosine nitrogen is icosanoyl. A constituent of natural ganglioside GM2.


A beta-D-galactosyl-(1<->1')-N-acylsphinganine in which the acyl group is specified as tetracosanoyl.


A ceramide that is the N-(2-hydroxytetracosanoyl) derivative of 4-hydroxyeicosasphinganine.


hydroxylamines

Hydroxylamine, H2N-OH, and its hydrocarbyl derivatives.


ETHYL NITROSOUREA

A member of the class of N-nitrosoureas that is urea in which one of the nitrogens is substituted by ethyl and nitroso groups.


N-glycosylated glycine

A glycine derivative in which a glycosyl group is linked to the glycine molecule through its N atom.


amino acid derivative

Any derivative of an amino acid resulting from reaction at an amino group, carboxy group, side-chain functional group, or from the replacement of any hydrogen by a heteroatom. The definition normally excludes peptides containing amino acid residues.


THIAZOMYCIN

A  heterodetic cyclic peptide isolated from Amycolatopsis fastidiosa.


L-threonine derivative

A proteinogenic amino acid derivative resulting from reaction of L-threonine  at the amino group or the carboxy group, or from the replacement of any hydrogen of L-threonine  by a heteroatom.


An N-acyl-1-O-beta-D-glucosyl-15-methylhexadecasphing-4-enine in which the acyl group has 17 carbons and 0 double bonds and is 2-hydroxylated.


An amino trisaccharide consisting of two beta-D-galactopyranose residues and a 2-acetamido-2-deoxy-D-glucopyranose residue joined in sequence by (1->6) glycosidic bonds.


A glycophytoceramide having an alpha-D-galactopyranosyl residue at the O-1 position and a palmitoyl (hexadecanoyl) group attached to the nitrogen.


taltirelin

An oligopeptide comprising of (4S)-1-methyl-2,6-dioxohexahydropyrimidine-4-carboxylic acid, L-histidine and L-prolinamide joined in sequence by peptide linkages. It is a thyrotropin-releasing hormone (TRH) analog. Its tetrahydrate form is approved in Japan for the treatment of spinal muscular atrophy.


mononitroglycerol

A nitroglycerol that is glycerol in which one nitro group replaces the hydrogen(s) attached to one of the hydroxy groups.


Asp-Leu-Thr-Ser

A tetrapeptide composed of L-aspartic acid, L-leucine, L-threonine and L-serine joined in sequence by peptide linkages.


Ile-Leu-Trp-Trp

A tetrapeptide composed of L-isoleucine, L-leucine and two L-tryptophan units joined in sequence by peptide linkages.


A glycotetraosylceramide having beta-D-galactosyl-(1->4)-N-acetyl-beta-D-galactosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucose as the tetrasaccharide component.


A cationic C3 cyanine dye having benzothiazolium-2-yl and quinolinium-4-yl substituents.


A ceramide obtained by formal condensation of the carboxy group of icosanoic acid with the amino group of (4E,14Z)-sphinga-4,14-dienine.


GlyTouCan G09197ZW

A composition-only glycan consisting of six hexosyl groups, four acetaminohexosyl groups and one 6-deoxyhexosyl group (identities and connectivity unknown). Composition: Hex6 HexNAc4 dHex1.


Asp-Leu-Phe-Val

A tetrapeptide composed of L-aspartic acid, L-leucine, L-phenylalanine and L-valine joined in sequence by peptide linkages.


KETOTIFEN FUMARATE

An organoammonium salt consisting of equimolar amounts of ketotifen(1+) and fumarate(1-) ions. A blocker of histamine H1 receptors with a stabilising action on mast cells, it is a non-bronchodilator anti-asthmatic drug.


oxidized ceramide

Any ceramide having an oxidized fatty acyl component.


A glucosylceramide consisting of a beta-D-glucosyl residue attached to the primary hydroxyl group of N-acylpentadecasphingosine.


Asp-Pro-Ser-Ser

A tetrapeptide composed of L-aspartic acid, L-proline and two L-serine units joined by peptide linkages.


An N-acyl-1-O-beta-D-glucosyl-15-methylhexadecasphing-4-enine in which the acyl group has 19 carbons and 4 double bonds and is 2-hydroxylated.


MOPS

An oxygen molecular entity that acts as an excellent buffer for many biological systems at near-neutral pH.


A sialotriosylceramide that consists of a beta-D-GalNAc-(1->4)-[alpha-Neu5Ac-(2->3)]-beta-D-Gal-(1->4)-beta-D-Glc moiety attached via a glycosidic bond at position 1 of N-acylicosasphingosine.


A beta-D-glucosylceramide in which a beta-D-glucosyl residue attached to the primary hydroxyl group of N-tricosanoyl-14-methylhexadecasphingosine. It is a metabolite of the nematode Caenorhabditis elegans.


polyamine

Any organic amino compound that contains two or more amino groups.


Glu-Trp-Asp-Arg

A tetrapeptide composed of L-glutamic acid, L-tryptophan, L-aspartic acid, and L-arginine joined in sequence by peptide linkages.


nitrohydrocarbon

A C-nitro compound that is a hydrocarbon in which one or more of the hydrogens has been replaced by nitro groups.


vancomycin

A complex glycopeptide from Streptomyces orientalis. It inhibits a specific step in the synthesis of the peptidoglycan layer in the Gram-positive bacteria Staphylococcus aureus and Clostridium difficile.


A sphingoid that is sphingosine having an additional trans-double bond at position 8.


etrasimod arginine

An organoammonium salt obtained by combining etrasimod with one molar equivalent of L-arginine. It is a sphingosine 1-phosphate receptor modulator approved for the treatment of moderately to severely active ulcerative colitis in adults.


carbocyanin DBTC(1+)

A symmetrical C3 cyanine dye having 1-ethylnaphtho[1,2-d][1,3]thiazol-2-yl groups at each end.


A glycopentaosylceramide having beta-D-galactosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->6)]-N-acetyl-beta-D-galactosaminyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosyl component attached to the primary hydroxy function of a ceramide with undefined sphingoid base.


A glucosylceramide consisting of a beta-D-glucosyl residue attached to the primary hydroxyl group of N-acyl-(4E,6E)-pentadecasphingadienine.


Ala-Leu-Leu-His

A tetrapeptide composed of L-alanine, two L-leucine units, and an L-histidine joined in sequence.


Ala-Thr-Ala-Pro

A tetrapeptide composed of L-alanine, L-threonine, L-alanine, and L-proline joined in sequence by peptide linkages.


A ceramide in which the sphingoid component is specified as (4E,8E)-9-methylsphinga-4,8-dienine.


An aromatic ether comprised of phenetole substituted at C-2 and C-4 by nitro groups.


METHYL PHOSPHONATE

A one-carbon compound that is phosphonic acid in which the hydrogen attached to the phosphorus is substituted by a methyl group.


L-phenylalanine derivative

A proteinogenic amino acid derivative resulting from reaction of L-phenylalanine  at the amino group or the carboxy group, or from the replacement of any hydrogen of L-phenylalanine  by a heteroatom.


A D-galactosyl-N-acylsphingosine in which a beta-D-galactosyl residue is attached to the primary hydroxy group of any N-(2-hydroxyacyl)sphingosine.


tyrocidine D

A homodetic cyclic decapeptide consisting of D-Phe, L-Pro, L-Trp, D-Trp, L-Asn, L-Gln, L-Trp, L-Val, L-Orn, and L-Leu residues coupled in sequence and cyclised head-to-tail.


An amino trisaccharide consisting of alpha-L-fucopyranosyl, 2-acetamido-beta-D-glucosyl and D-mannopyranosyl residues linked in sequence by (1->3) and (1->2) glycosidic linkeages.


N-nitrosoureas

A nitroso compound that is any urea in which one of the nitrogens is substituted by a nitroso group


A sialotriaosylceramide consisting of a linear pentasaccharide made up from two N-acetylneuraminyl residues, an N-acetyl-6-O-[(2-aminoethoxy)(hydroxy)phosphoryl]-beta-D-glucosaminyl residue, a mannosyl residue and a glucosyl residue at the reducing end attached to the ceramide portion via a beta-linkage.


N-METHYL-N-NITROSUREA

A member of the class of N-nitrosoureas that is urea in which one of the nitrogens is substituted by methyl and nitroso groups.


ganglioside GM2 (18:0) amide

A sialotriaosylceramide that is ganglioside GM2 (18:0) in which the carboxy function of the sialic acid residue has been converted into a carboxamide.


An N-acetyl-beta-D-glycosaminyl glycopeptide consisting of an N-acetyl-beta-D-glycosaminyl-(1->4)-N-acetylmuramoyl moiety attached to the amino terminus of the pentapeptide L-Ala-gamma-D-Glu-N(6)-(beta-D-Asp)-L-Lys-D-Ala-D-Ala via an amide linkage.


ammonium compound

Compounds (NH4(+))Y(-) and derivatives, in which one or more of the hydrogens bonded to nitrogen have been replaced with univalent groups.


epichlicin

A homodetic cyclic peptide containing L-Pro, D-Tyr, L-Ser, L-Asn and L-Gln as the amino acid residues. Isolated from an endophytic fungus, Epichloe typhina, it exhibits inhibitory activity toward the spore germination of Cladosporium phlei, a pathogenic fungus of the timothy plant.


name: (2S)-2-[[(2-chlorophenyl)-oxomethyl]amino]-3-methylbutanoic acid (3-cyano-4-imino-2-oxopentyl) ester


A dinitrotoluene carrying nitro substituents at positions 2 and 6.


Asp-Met-Met-Cys

A tetrapeptide composed of L-aspartic acid, two L-methionine units, and a L-cysteine joined in sequence by peptide linkages.


bleomycin A5

A member of the class of bleomycins that is used in sclerotherapy for cervicofacial lymphatic malformations.


1-aminocyclopropylphosphonic acid

A member of the class of phosphonic acids that is phosphonic acid in which the hydrogen attached to the phosphorus is substituted by a 1-aminocyclopropyl group.


An amino tetrasaccharide that is alpha-L-Fucp-(1->2)-beta-D-Galp-(1->3)-D-GalpNAc in which the hydroxy group at position 4 of the beta-D-galactopyranosyl moiety has been glycosylated by an alpha-D-galactopyranosyl group.


name: ganglioside GM2 (18:0) NeuAc-C7-de(1,2,-dihydroxyethyl)

description: A sialotriaosylceramide that is ganglioside GM2 (18:0) in which the sialo residue is truncated at C-7.


Gln-Leu-Leu-Pro

A tetrapeptide composed of L-glutamine, two L-leucine units and L-proline joined in sequence by peptide linkages.


HYDROXYAMINE

The simplest hydroxylamine, consisting of ammonia bearing a hydroxy substituent. It is an intermediate in the biological nitrification by microbes like bacteria.


A beta-D-glucoside that is the 2-azidoethyl glycoside of a tetrasaccharide (Streptococcus pneumoniae serotype 14 tetrasaccharide) consisting of at the reducing end an N-acetyl-beta-D-glucosamine residue to which are linked (1->4) and (1->6) respectively a beta-D-glucose residue and a beta-D-galactosyl-(1->4)-beta-D-glucosyl disaccharide unit.


An N-acyl-D-galactosylsphingosine in which the ceramide N-acyl group is composed of 26 carbons, 1 double bond and a hydroxy group at C2.


NEUROTENSIN

A 13 amino acid peptide hormone which is found in the central nervous system and the gastrointestinal tract. It behaves as a neurotransmitter in the brain, as a hormone in the gut, and also as a neuromodulator. It is implicated in the pathophysiology of several CNS disorders (including schizophrenia, Parkinson's disease, drug abuse, pain, cancer, inflammation, eating disorders and central control of blood pressure) due to its association with a wide variety of neurotransmitter systems such as dopaminergic, sertonergic, glutamatergic, GABAergic, and cholinergic systems.


hydroxyurea

A member of the class of ureas that is urea in which one of the hydrogens is replaced by a hydroxy group. An antineoplastic used in the treatment of chronic myeloid leukaemia as well as for sickle-cell disease.


phosphonoacetaldehyde

A phosphonic acid consisting of acetaldehyde with the phospho group at the 2-position.


N-acylethanolamine phosphate

Any carboxamide resulting from the formal condensation of a carboxylic acid with the amino group of O-phosphoethanolamine (2-aminoethyl dihydrogen phosphate).


A glycophytoceramide having an alpha-D-galactopyranosyl residue at the O-1 position and an 8-phenyloctanoyl group attached to the nitrogen.


A ceramide obtained by formal condensation of the carboxy group of hexadecanoic acid with the amino group of 14-methylhexadecasphingosine. It is a metabolite of the nematode Caenorhabditis elegans.


A sialopentaosylceramide consisting of a alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-beta-D-GalNAc-(1->4)-[alpha-Neu5Ac-(2->3)]-beta-D-Gal-(1->4)-beta-D-Glucosyl unit attached to a Cer(d18:1/23:0).


phytochelatin 3

A phytochelatin that is a heptapeptide consisting of 3 units of gamma-Glu-Cys, with a glycyl unit at the C-terminus.


An amino trisaccharide consisting of alpha-L-fucopyranose, alpha-L-arabinopyranose and 2-acetamido-2-deoxy-beta-D-glucopyranose residues joined in sequence by (1->2) and (1->3) glycosidic bonds.


An amino trisaccharide consisting of 2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-galactopyranose and D-glucopyranose residues joined in sequence by (1->6) and (1->4) glycosidic bonds.


An N-acyl-1-O-beta-D-glucosyl-15-methylhexadecasphing-4-enine in which the acyl group has 23 carbons and 0 double bonds and is 2-hydroxylated.


Cys-Phe-Phe-Gly

A tetrapeptide composed of L-cysteine, two L-phenylalanine units and glycine joined in sequence by peptide linkages.


N-acetylglycine-N-methylamide

An amino acid amide that is methylglycinamide with an acetyl group substituent on the amino group.


An oligoglycosylceramide consisting of a branched nonasaccharide made up from five sialyl residues, two galactose residues, one N-acetylgalactosamine residue and a glucose residue at the reducing end attached to N-acylsphingosine via a beta-linkage.


An amino trisaccharide consisting of alpha-L-fucopyranosyl, 2-acetamido-2-deoxy-beta-D-glucopyranosyl and D-galactopyanosyl residues joined together in sequence by (1->3) and (1->2) glycosidic linkages.


reactive nitrogen species

A family of nitrogen molecular entities which are highly reactive and derived from nitric oxide (.NO) and superoxide (O2.(-)) produced via the enzymatic activity of inducible nitric oxide synthase 2 (NOS2) and NADPH oxidase respectively.


azoxy compound

An N-oxide of an azo compound of structure RN=N(+)(O(-))R.


A ceramide that is the N-(2-hydroxyhexadecanoyl) derivative of 4-hydroxyeicosasphinganine.


A ceramide where the acyl chain chain length is greater than C27 and the sphingoid base is undefined


A glycophytoceramide having a 6-deoxy-6-(N'-naphthoureido)-alpha-D-galactosyl residue at the O-1 position and a hexacosanoyl group attached to the nitrogen.


BUTAMBEN PICRATE

An organoammonium salt resulting from the formal reaction of butamben with 0.5 mol eq. of picric acid.


4-nitrophenyl alpha-L-fucoside

An alpha-L-fucoside that is alpha-L-fucopyranose in which the anomeric hydroxy hydrogen is replaced by a 4-nitrophenyl group.


N-acetylhexosaminyl-dihexosylceramide

A glycotriaosylceramide in which the trisaccharide portion includes one N-acetyl hexosaminyl residue and two hexosyl residues.


A dinitrotoluene in which the methyl group is meta to one of the nitro groups and para to the other. A uellow crystalline compound that is virtually insoluble in water but dissolves in most organic solvents.


Any ceramide in which the primary hydroxy hydrogen has been replaced by an acyl group.


A tricarboxylic acid triamide resulting from the formal condensation of the each carboxy group or benzene-1,3,5-tricarboxylic acid with the primary amino group of a molecule of 3-aminopyridine.


A dihydroceramide in which the acyl moiety contains 24 carbons, 1 double bond, and a hydroxyl group on position 2.


furanilide fungicide

Any anilide fungicide whose structure contains a furanilide group [ArC(=O)N(R)Ar', where Ar is a furanyl or substituted furanyl group and Ar' is a phenyl or substituted phenyl group].


N-palmitoyl-sphingoid base

A ceramide where the N-acyl is a palmitoyl chain but the sphingoid base is not defined


A dihydroceramide in which the ceramide N-acyl group is specified as 2-hydroxyhexadecanoyl


A glycosyl alditol derivative consisting of beta-D-galactopyranose and N-acetyl-D-galactosaminitol joined in sequence by a (1->3) glycosidic bond.


(acetamidomethyl)phosphonic acid

A member of the class of acetamides obtained by formal condensation of acetic acid with the amino group of (aminomethyl)phosphonic acid.


An N-acyl-D-galactosylsphingosine in which the ceramide N-acyl group is composed of 25 carbons  and a hydroxy group at C2.


A spermidine hydroxycinnamic acid conjugate in which N-1 and N-5 of spermidine have formed amide bonds with a molecule each of 5-hydroxyferulic acid and N-10 has formed an amide bond with sinapic acid.


A sialotetraosylceramide consisting of a linear pentasaccharide made up from one sialyl residue, two galactose residues, one N-acetylgalactosamine residue and a glucose residue at the reducing end attached to the ceramide portion via a beta-linkage.


An N-acyl-1-O-beta-D-glucosyl-15-methylhexadecasphing-4-enine in which the acyl group has 21 carbons and 2 double bonds.


Cy7 dye

A C7-cyanine dye having differentially-substituted 2-indolyl units at each end.


Ala-Val-Pro-Pro

A tetrapeptide composed of L-alanine, L-valine, and two L-proline units joined in sequence by peptide linkages.


N-octacosanoylsphinganine

A dihydroceramide that is the N-(octacosanoyl) derivative of sphinganine.


Arg-Asn-Gly-Ser

A tetrapeptide composed of L-arginine, L-asparagine, glycine, and L-serine joined in sequence by peptide linkages.


GlyTouCan G08590QR

A composition-only glycan consisting of three hexosyl groups and one acetaminohexosyl group (identities and connectivity unknown). Composition: Hex3 HexNAc1.


An oligopeptide composed of L-asparagine, L-proline, L-valine, L-valine, L-histidine, L-phenylalanine, L-phenylalanine, L-lysine, L-asparagine, L-isoleucine, L-valine, L-threonine, L-proline, L-arginine, L-threonine, L-proline, L-proline, L-proline and L-serine joined in sequence by peptide linkages.


A glycophytoceramide having a 4-O-[3-(4-methoxyphenyl)propyl]-alpha-D-galactosyl residue at the O-1 position and a hexacosanoyl group attached to the nitrogen. One of a series of an extensive set of 4"-O-alkylated alpha-GalCer analogues evaluated (PMID:30556652) as invariant natural killer T-cell (iNKT) antigens.


A beta-D-galactosyl-(1<->1')-N-acylsphinganine in which the acyl group is specified as (15Z)-tetracosenoyl.


TYROCIDINE A

A homodetic cyclic decapeptide consisting of D-Phe, L-Pro, L-Phe, D-Phe, L-Asn, L-Gln, L-Tyr, L-Val, L-Orn, and L-Leu residues coupled in sequence and cyclised head-to-tail.


salicylaldehyde N-tosylimines

Salicylaldehyde imines with a tosyl (toluene-p-sulfonyl) group bonded to the imine N atom.


A C20 phytoceramide in which the ceramide N-acyl group is specified as 2-hydroxytetradecanoyl.


A carboxamide consisting of a 1-hydroxyoctadecan-2-yl moiety linked via nitrogen to tetracosanamide. A ceramide mimetic, it is composed of a saturated C18-phytosphingosine and lignoceric acid (C24:0).


A glycooctaosylceramide having beta-D-Galp-(1->4)-beta-D-GlcpNAc-(1->3)-[beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->6)]-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc as the oligoglycosyl component.


GlyTouCan G62765YT

A partially-defined glycan consisting of 8 hexosyl and 2 acetaminohexosyl groups (identities and connectivity unknown). Composition: Hex8 HexNAc2.


An amino trisaccharide that is alpha-D-galactopyranose in which the hydroxy groups at positions 2 and 3 have been glycosylated by alpha-L-fucopyranosyl and 2-acetamido-alpha-D-galactopyranosyl groups, respectively.


Ala-Ala-Asp-Asp

A tetrapeptide composed of two L-alanine units linked to two L-aspartic acid units by peptide linkages.


Schiff base

An imine bearing a hydrocarbyl group on the nitrogen atom R2C=NR' (R' =/= H).


primary diamine

A primary diamine is a compound derived from a hydrocarbon by replacing two hydrogen atoms by amino groups.


pentaerithrityl tetranitrate

A pentaerythritol nitrate in which all four hydroxy groups of pentaerythritol have been converted to the corresponding nitrate ester. It is a vasodilator with properties similar to those of glyceryl trinitrate, but with a more prolonged duration of action, and is used for treatment of angina pectoris. It is also one of the most powerful high explosives known and is a component of the plastic explosive known as Semtex.


N-glycolylneuraminyllactosylceramide

A sialotriaosylceramide in which the triaosyl group is 3,5-dideoxy-5-(2-hydroxyacetamido)-D-glycero-alpha-D-galacto-non-2-ulopyranonosyl-(2->3)-beta-D-galactopyranosyl-(1->4)-beta-D-glucopyranosyl attached to the primary hydroxy function of ceramide. A tumour antigen found in solid tumors such as breast carcinoma, nonsmall cell lung cancer, and melanoma, but not usually detected in normal human cells.


A sialotetraosylceramide consisting of a branched heptasaccharide made up from three sialyl residues, two galactose residues, one N-acetylglucosamine residue and a glucose residue at the reducing end attached to the ceramide portion via a beta-linkage.


A sialohexaosylceramide consisting of a linear heptasaccharide made up from one glycolylneuraminyl residue, three galactose residues, two N-acetylglucosamine residues and one glucose residue, which at the reducing end is attached to the ceramide portion via a beta-linkage.


vitamin B12

Any member of a group of cobalamin vitamers that exhibit biological activity against vitamin B12 deficiency. Vitamin B12 deficiency is associated with low red blood cell count and anemia. The vitamers are found in foods such as cereals, meat, fish, and poultry. The vitamers include adenosylcobalamin, hydroxocobalamin, cyanocobalamin, aquacobalamin, nitritocobalamin and methylcobabalamin (also includes their ionized, salt and phosphate derivatives).


Ala-Leu-Leu-Ser

A tetrapeptide composed of L-alanine, two L-leucine units, and L-serine joined in sequence by peptide linkages.


A beta-D-glucosylceramide obtained by formal condensation of the carboxy group of henicosanoic acid with the amino group of beta-D-glucosyl-(1<->1')-(4E,14Z)-sphingadienine.


An amino disaccharide consisting of a beta-D-glucopyranose residue and a 2-acetamido-2-deoxy-D-glucopyranose residue joined in sequence by a (1->3) glycosidic bond.


glycooctaosylceramide

An oligoglycosylceramide consisting of a glycooctaosyl moiety attached to the ceramide oxygen with an unspecified N-acyl substituent attached to the ceramide nitrogen.


An amino disaccharide consisting of alpha-D-glucopyranose and 2-acetamido-2-deoxyalpha-D-galactopyranose residues joined in sequence by a (1->3) glycosidic bond.


primary amide

A derivative of an oxoacid RkE(=O)l(OH)m (l =/= 0) in which an acidic hydroxy group has been replaced by an amino or substituted amino group.


GlyTouCan G06356OH

An amino decasaccharide consisting of five hexosyl groups, four acetaminohexosyl groups and an N-acetcylneuraminic acid group (identities and connectivity unknown). Composition: Hex5 HexNAc4 Neu5Ac1.


oxime O-ether

O-organyl oximes R2C=NOR' (R' =/= H).


A  N-acyl-beta-D-galactosylsphingosine in which the acyl group is specified as tricosanoyl.


BRADYKININ

A linear nonapeptide messenger belonging to the kinin group of proteins, with amino acid sequence RPPGFSPFR. Enzymatically produced from kallidin in the blood, it is a powerful vasodilator that causes smooth muscle contraction, and may mediate inflammation.


hexadecasphingosine-based sphingolipid

A family of sphingolipids that share a common structural feature, a hexadecasphingosine base backbone.


name: 2-[2-[[1-oxo-2-[(5-pyridin-4-yl-1,3,4-oxadiazol-2-yl)thio]ethyl]amino]-4-thiazolyl]acetic acid ethyl ester


acetyl-amino acid

Any amino acid derivative that is the N-acetyl or O-acetyl derivative of an amino acid.


A ceramide obtained by formal condensation of the carboxy group of docosanoic acid with the amino group of 14-methylhexadecasphingosine. It is a metabolite of the nematode Caenorhabditis elegans.


kinetensin (1-8)

An 8 amino acid oligopeptide fragment of kinetensin lacking the C-terminal L-leucine residue.


isoproturon-monodemethyl

A member of the class of phenylureas that is 1-methylurea substituted by a p-cumenyl group at position 3. It is a metabolite of the herbicide isoproturon.


azo compound

Derivatives of diazene with the general structure R-N=N-R'.


An amino disaccharide consisting of 2-acetamido-beta-D-glucopyranose and D-mannopyranose residues joined in sequence by a (1->6) glycosidic bond.


microcin B17

A 43-membered microcin composed of Val, Gly, Ile, Gly, Gly, Gly, Gly, Gly, Gly, Gly, Gly, Gly, Gly, Ser, Cys, Gly, Gly, Gln, Gly, Gly, Gly, Cys, Gly, Gly, Cys, Ser, Asn, Gly, Cys, Ser, Gly, Gly, Asn, Gly, Gly, Ser, Gly, Gly, Ser, Gly, Ser, His and Ile residues joined in sequence.


A guanidine that consists of agmatine having a 3-aminopropyl group attached to the N-1 position.


name: 2-[4-(dimethylamino)phenyl]azobenzoic acid [2-(1-azepanyl)-2-oxoethyl] ester


microcystin LW

A microcystin consisting of D-alanyl, L-leucyl, (3S)-3-methyl-D-beta-aspartyl, L-tryptophanyl, (2S,3S,4E,6E,8S,9S)-3-amino-4,5,6,7-tetradehydro-9-methoxy-2,6,8-trimethyl-10-phenyldecanoyl, D-gamma-glutamyl, and 2,3-didehydro-N-methylalanyl residues joined into a 25-membered macrocycle.


A glycotetraosylceramide having beta-D-galactosyl-(1->3)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl component attached to the primary hydroxy function of a ceramide with undefined sphingoid base.


name: 2-[[oxo-(5-propyl-3-isoxazolyl)methyl]amino]benzoic acid methyl ester


A glycotriaosylceramide having N-acetyl-beta-D-galactosyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosyl as the triaosyl component.


Ala-Leu-Asp-Asp

A tetrapeptide composed of L-alanine, L-leucine, and two L-aspartic acid units joined in sequence by peptide linkages.


An amino trisaccharide consisting of 2-acetamido-2-deox-beta-D-glucoyranosyl, beta-D-mannopyranosyl and 2-acetamido-2-deoxy-D-glucopyranosyl residues joined in sequence by (1->4) glycosidic linkages.


2-methylpropanal oxime

An aldoxime derived from 2-methylpropanal.


A synthetic tetrapeptide comprising Ac-Cha, Arg, Tic and  Nle-NHCH2CH2Ph residues coupled in sequence.


cyclohexyl isocyanide

An isocyanide having a cyclohexyl group attached to nitrogen.


N-nitrososarcosine

A nitrosamine that is sarcosine in which the hydrogen attached to the nitrogen has been replaced by a nitroso group.


A N-acyl-beta-D-galactosylsphingosine in which the acyl group specified is (17Z)-hexacosenoyl.


A fifteen-membered glycopeptide comprising glycyl, isoleucyl, alanyl, glycyl, 4-fluorophenylalanyl, (5R)-5-(beta-D-galactopyranosyloxy)lysyl, glycyl. alpha-glutamyl, glutaminyl, glycyl, prolyl, lysyl, glycyl, alpha-glutamyl and threonine residues coupled in sequence.


A glycophytoceramide having an alpha-D-glucopyranosyl residue at the O-1 position and an tetracosanoyl group attached to the nitrogen.


acylamino acid fungicide

An amide fungicide whose structure contains an acylamino acid skeleton.


name: 4-[[oxo-(1-phenyl-3-pyridin-4-yl-4-pyrazolyl)methyl]amino]benzoic acid methyl ester


A glycophytoceramide having a 4-O-[3-(3,4-dichlorophenyl)propyl]-alpha-D-galactosyl residue at the O-1 position and a hexacosanoyl group attached to the nitrogen. One of a series of an extensive set of 4"-O-alkylated alpha-GalCer analogues evaluated (PMID:30556652) as invariant natural killer T-cell (iNKT) antigens.


SUBSTANCE P

A neuropeptide consisting of 11-amino acids. It preferentially activates neurokinin-1 receptors, exterting excitatory effects on central and peripheral neurons and involved in pain transmission.


An N-acyl-15-methylhexadecasphing-4-enine in which the acyl group has 18 carbons and 0 double bonds and is 2-hydroxylated.


An amino trisaccharide that is D-galactopyranose in which the hydroxy groups at positions 2 and 3 have each been converted into the corresponding 2-acetamido-2-deoxy-beta-D-glucopyranosyl derivative.


A sialopentaosylceramide consisting of a alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-beta-D-GalNAc-(1->4)-[alpha-Neu5Ac-(2->3)]-beta-D-Gal-(1->4)-beta-D-Glucosyl unit attached to a Cer(d18:1/22:0).


A glycotriaosylceramide having alpha-D-galactosyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosyl as the glycotriaosyl component attached to the Cer(d18:1/24:0).


thionylimide

An imide in which an imino group and an oxo group are both attached to an atom of sulfur.


N-tetradecanoylicosasphinganine

A C20 dihydroceramide in which the ceramide N-acyl group is specified as tetradecanoyl (myristoyl).


p-nitrobenzyl glutaryl glycinic acid

A glycine derivative in which a glycine core carries an N-{5-[(4-nitrobenzyl)amino]-5-oxopentanoyl} substituent.


A polyamide consisting of hexane-1,6-diamine having a 1-{(2S)-2-cyclohexyl-2-[(N-methyl-L-alanyl)amino]acetyl}-L-prolyl-beta-phenyl-L-phenylalanyl moiety attached to both nitrogens.


hexadecasphinganine-based sphingolipid

A family of sphingolipids that share a common structural feature, a hexadecasphinganine base backbone.


Asn-Trp-Asp-Ser

A tetrapeptide composed of L-asparagine, L-tryptophan, L-aspartic acid and L-serine joined in sequence by peptide linkages.


N-tricosanoyl-D-galactosylsphingosine

An N-acyl-D-galactosylsphingosine in which the ceramide N-acyl group is specified as tricosanoyl


An amino trisaccharide consisting of alpha-L-fucopyranose, 3-O-methyl-beta-D-galactopyranose and 2-acetamido-2-deoxy-D-glucopyranose residues joined in sequence by (1->2) and (1->4) glycosidic bonds.


A glycophytoceramide having an alpha-D-galactopyranosyl residue at the O-1 position and an 11-(4-fluorophenyl)undecanoyl group attached to the nitrogen.


An amino trisaccharide consisting of a 2-acetamido-2-deoxy-beta-D-mannopyranose residue and two beta-D=glucopyranose residues joined in sequence by (1->4) glycosidic bonds.


An amino trisaccharide consisting of beta-D-glucopyranuronic acid, 2-acetamido-2-deoxy-alpha-D-glucopyranose and beta-D-glucopyranuronic acid residues joined in sequence by (1->4) glycosidic bonds.


A glycophytoceramide having an 6-O-(3-phenylpropanoyl)-alpha-D-galactosyl residue at the O-1 position and a hexacosanoyl group attached to the nitrogen; a C6"-modified alpha-GalCer derivative.


An amino trisaccharide consisting of alpha-L-fucopyranose, 3-deoxy-beta-D-xylo-hexopyranose and 2-acetamido-2-deoxy-beta-D-glucopyranose residues joined in sequence by (1->2) and (1->3) glycosidic bonds.


D-tryptophan derivative

A non-proteinogenic amino acid derivative resulting from reaction of D-tryptophan  at the amino group or the carboxy group, or from the replacement of any hydrogen of D-tryptophan  by a heteroatom.


A beta-D-galactosyl-(1<->1')-N-acylsphinganine in which the acyl group specified is (17Z)-hexacosenoyl.


sialoheptaosylceramide

A ganglioside in which the oligosaccharide portion is composed of a heptasaccharide, to which one or more sialic acid residues are attached.


A sialotriaosylceramide consisting of beta-D-GalNAc-(1->4)-[alpha-Neu5Ac-(2->3)]-beta-D-Gal-(1->4)-beta-D-Glc attached to the primary hydroxy function of ceramide(d18:1/21:0).


A branched glycooctaosylceramide having alpha-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->6)-[beta-D-GlcNAc-(1->3)]-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc as the glycooctaosyl component.


A galactosylceramide with a proposed structure in which an alpha-galactose residue is linked glycosidically to a sphingoid backbone with substituents -C(=O)Cn(OH)H2n on nitrogen and -C31-n(OH)H62-2n on C-2. Obtained from the intestinal microbe Bacteroides fragilis NCTC 9343. In the structural diagram R1 = Cn(OH)H2n and R2 = C31-n(OH)H62-2n.


This compound belongs to the class of organic compounds known as glycosylamines. These are compounds consisting of an amine with a beta-N-glycosidic bond to a carbohydrate, thus forming a cyclic hemiaminal ether bond (alpha-amino ether).


Ala-Val-Asp-His

A tetrapeptide composed of L-alanine, L-valine, L-aspartic acid, and L-histidine joined in sequence by peptide linkages.


A glycoside comprising beta-lactose having a p-(p-dimethylaminophenylazo)phenyl group at the 1-position.


A glycotriaosylceramide having alpha-D-galactosyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosyl as the glycotriaosyl component attached to the Cer(d18:1/24:1(15Z)).


capuride

An N-acylurea in which the acyl substituent is 2-ethyl-3-methylpentanoyl. A monoureide sedative, it has a duration of hypnotic effect similar to that of the short-acting barbiturates.


Ac-Cha-Gpg-Tic-Nle-NMeBn

A synthetic tetrapeptide composed of the non-natural Ac-Cha, Gpg, Tic and Nle-NMeBn residues coupled in sequence.


8-(methylsulfanyl)octanal oxime

An aliphatic aldoxime resulting from the formal condensation of 8-(methylsulfanyl)octanal with hydroxylamine.


An amino pentasaccharide that is beta-D-Manp-(1->4)-beta-D-GlcpNAc-(1->4)-beta-D-GlcpNAc in which the mannosyl group has been glycosylated by alpha-D-mannopyranosyl groups at positions 3 and 6.


BISTRATAMIDE F

A homodetic cyclic peptide that consists of L-threonine and L-valine and L-serine as the amino acid residues cyclised via amide bonds. It is isolated from Lissoclinum bistratum and exhibits antitumour activity against the human colon tumour cell line


An amino trisaccharide that is 2-acetamido-2-deoxy-beta-D-glucopyranose in which the hydroxy groups at positions 3 and 4 have been converted to the corresponding beta-D-galactopyranosyl and 4,6-dideoxy-alpha-L-xylo-hexopyranosyl derivatives, respectively.


A trisubstituted guanidine, carrying 4-cyanophenyl, diphenylmethyl and carboxymethyl substituents, which is known to act as a highly potent sweetening agent.


A glycophytoceramide having an alpha-lactosyl residue at the O-1 position and a hexacosanoyl group attached to the nitrogen.


Asn-Leu-Phe-Asp

A tetrapeptide composed of L-asparagine, L-leucine, L-phenylalanine and L-aspartic acid joined in sequence by peptide linkages.


A D-galactosyl-N-acylsphingosine where the ceramide N-acyl group is nervonoyl [(15Z)-tetracos-15-enoyl] and the D-galactosyl component has beta anomeric configuration.


A glycopeptide that consists of glycyl, phenylalanyl, (5R)-5-(beta-D-galactopyranosyloxy)lysyl, glycyl. alpha-glutamyl, glutaminyl, glycyl, prolyl, lysyl, glycyl, alpha-glutamyl and threonine residues coupled in sequence with an isostere-modified IlePsi[(E)-CH=CH]Ala group attached to the amino terminus.


An N-acyl-15-methylhexadecasphing-4-enine in which the acyl group has 22 carbons and 0 double bonds.


A phosphonic acid consisting of 1-cyclopentyluracil having a phosphomethoxy group at position 2 on the cyclopentyl ring with (1R,2R)-trans-stereochemistry.


A 1-O-acyl-N-acylsphingosine in which the N- and O-acyl groups are specified as acetyl and (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl respectively.


microcystin-LR

A microcystin consisting of D-alanyl, L-leucyl, (3S)-3-methyl-D-beta-aspartyl,L-arginyl, 2S,3S,4E,6E,8S,9S)-3-amino-4,5,6,7-tetradehydro-9-methoxy-2,6,8-trimethyl-10-phenyldecanoyl, D-gamma-glutamyl, and 2,3-didehydro-N-methylalanyl residues joined into a 25-membered macrocycle. Produced by the cyanobacterium Microcystis aeruginosa, it is the most studied of the microcystins.


deferrichrome

A homodetic cyclic peptide composed from two units of three glycyl and three N(5)-acetyl-N(5)-hydroxy-L-ornithyl residues.


A synthetic six-membered oligopeptide comprising Ac-Cha, Arg, Ala, Odapdc, Ser and Leu-NH2 residues coupled in sequence.


A nucleoside analogue in which adenosine has been modified by substitution at C-2 by a methylthio (methylsulfanyl) group and at the 6-amino nitrogen by a Delta(2)-isopentenyl group.


A macromolecule consisting of (6R)-5,10-methylenetetrahydrofolic acid with an arbitrary number of glutamic acid residues attached as a polypeptide to the single existent one.


An amino trisaccharide consisting of 2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-galactopyranose and 2-acetamido-2-deoxy-D-galactopyranose residues joined in sequence by (1->3) and (1->4) glycosidic bonds.


microcin c

A member of the family of microcins comprising a heptapeptide covalently liinked to 3-aminopropyl-AMP via an acylphosphoramide linkage. A potent inhibitor of aspartyl-tRNA synthetase.


longicalycinin A

A homodetic cyclic peptide composed of glycyl, L-phenylalanyl, L-tyrosyl, L-prolyl and L-phenylalanyl residues joined sequentially to give a 15-membered macrocycle. Isolated from Dianthus superbus var longicalycinus, it exhibits anti-cancer activity.


C3-indocyanine cation

The cationic form of a C3 cyanine dye having 1-ethyl-3,3-dimethylindoleinine units at each end.


name: 2-[[cyclohexyl(oxo)methyl]amino]acetic acid [2-[2-chloro-5-(trifluoromethyl)anilino]-2-oxoethyl] ester


PERINDOPRIL ARGININE

An organoammonium salt obtained by combining perindopril with one molar equivalent of L-arginine.


An amino trisaccharide consisting of beta-D-galactopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose and 2-acetamido-2-deoxy-D-glucopyranose residues joined in sequence by (1->4) glycosidic bonds.


An N-acyl-1-O-beta-D-glucosyl-15-methylhexadecasphing-4-enine in which the acyl group has 27 carbons and 0 double bonds and is 2-hydroxylated.


An aminotrisaccharide that is 2-acetamido-2-deoxy-D-glucopyranose in which the hydroxy groups at positions 4 and 6 have been glycosylated by a beta-D-galactopyranosyl group and a beta-D-glucopyranosyl group, respectively.


A trisaccharide consisting of two beta-D-galactopyranose residues and a 2-acetamido-2-deoxy-D-glucopyranose residue joined in sequence by (1->3) and (1->4) glycosidic bonds.


A galactosylceramide consisting of a beta-D-galactosyl residue attached to the primary hydroxyl group of N-acyl-(4E,8E)-9-methylsphinga-4,8-dienine.


A glycosphingolipid identical with alpha-galactosylceramide (alpha-GalCer) with the exception of the replacement of the C-2 carbonyl oxygen on the acyl chain with a sulfur atom.


A dihydroceramide in which the ceramide N-acyl group is specified as 2-hydroxydocosanoyl.


An N-icosenoylsphinganine in which the double bond is located at position 11 (the Z-geoisomer).


A glycophytoceramide having a 4-O-(5-phenylpentyl)-alpha-D-galactosyl residue at the O-1 position and a hexacosanoyl group attached to the nitrogen. One of a series of an extensive set of 4"-O-alkylated alpha-GalCer analogues evaluated (PMID:30556652) as invariant natural killer T-cell (iNKT) antigens.


N-carboxyglycine

A glycine derivative in which one of the hydrogens attached to the amino group bas been replaced by a carboxy group.


A glycophytoceramide having a 4-O-[4-(trifluoromethyl)benzyl]-alpha-D-galactosyl residue at the O-1 position and a hexacosanoyl group attached to the nitrogen. One of a series of an extensive set of 4"-O-alkylated alpha-GalCer analogues evaluated (PMID:30556652) as invariant natural killer T-cell (iNKT) antigens.


amide

An amide is a derivative of an oxoacid RkE(=O)l(OH)m (l =/= 0) in which an acidic hydroxy group has been replaced by an amino or substituted amino group.


Glu-Phe-Gln-Gln

A tetrapeptide composed of L-glutamic acid, L-phenylalanine and two L-glutamine units joined by peptide linkages.


(E)-2-methylpropanal oxime

A 2-methylpropanal oxime in which the oxime double bond has E geometry.


An amino trisaccharide consisting of a beta-D-mannopyranose residue and two 2-acetamido-2-deoxy-beta-D-glucopyranose residues joined in sequence by (1->4) glycosidic bonds.


GlyTouCan G05394UY

A composition-only glycan consisting of two hexosyl groups and one acetaminohexosyl group (identities and connectivity unknown). Composition: Hex2 HexNAc1.


amide antifungal agent

A compound that has significant antifungal properties whose structure contains an amide moiety.


isocyanates

Organonitrogen compounds that are derivatives of isocyanic acid; compounds containing the isocyanate functional group -N=C=O (as opposed to the cyanate group, -O-C#N).


A sialotriaosylceramide consisting of the hexasaccharide beta-GalNAc-(1->4)-[alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)]-beta-Gal-(1->4)-beta-Glc attached to the primary hydroxy function of ceramide(d18:1/18:0).


carbetocin

Oxytocin in which the hydrogen on the phenolic hydroxy group is substituted by methyl, the amino group on the cysteine residue is substituted by hydrogen, and the sulfur of the cysteine residue is replaced by a methylene group. A synthetic carba-analogue of oxytocin, it is used to control bleeding after giving birth. Like oxytocin, it causes contraction of the uterus.


A fifteen-membered glycopeptide comprising glycyl, cyclopropylalanyl, alanyl, glycyl, 4-pyridylylalanyl, (5R)-5-(beta-D-galactopyranosyloxy)lysyl, glycyl. alpha-glutamyl, glutaminyl, glycyl, prolyl, lysyl, glycyl, alpha-glutamyl and threonine residues coupled in sequence.


acetamides

Compounds with the general formula RNHC(=O)CH3.


Asn-Leu-Asp-Asp

A tetrapeptide composed of L-asparagine, L-leucine and two L-aspartic acid units joined in sequence by peptide linkages.


carbohydrazide

A hydrazide consisting of hydrazine carrying one or more carboacyl groups.


THIOACETAMIDE

A thiocarboxamide consiting of acetamide having the oxygen replaced by sulfur.


A sialotriaosylceramide consisting of beta-D-GalNAc-(1->4)-[alpha-Neu5Ac-(2->3)]-beta-D-Gal-(1->4)-beta-D-Glc attached to the primary hydroxy function of ceramide(d18:1/24:2), the position of the double bond in the tetracosadienoyl group being unspecified.


An aminotrisaccharide consisting of beta-D-galactopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose and L-furopyranose residues joined in sequence by (1->4) and (1->3) glycosidic bonds.


A glycophytoceramide having an alpha-D-galctopyranosyl residue at the O-1 position and a nonanoyl group attached to the nitrogen.


A fifteen-membered glycopeptide comprising glycyl, 2-aminoindane-2-formyl, alanyl, glycyl, cyclohexylalanyl, (5R)-5-(beta-D-galactopyranosyloxy)lysyl, glycyl. alpha-glutamyl, glutaminyl, glycyl, prolyl, lysyl, glycyl, alpha-glutamyl and threonine residues coupled in sequence.


An N-acyl-1-O-beta-D-glucosyl-15-methylhexadecasphing-4-enine in which the acyl group has 20 carbons and 4 double bonds and is 2-hydroxylated.


N-(hydroxymethyl)urea

A member of the class of ureas that is urea in which one of the amino hydrogens is replaced by a hydroxymethyl group.


A glycosyl alditol derivative consisting of N-acetyllactosamine and N-acetyl-D-galactosaminitol joined in sequence by a (1->6) glycosidic bond.


Asn-Asn-Pro-Ser

A tetrapeptide composed of two L-asparagine units, L-proline and L-serine joined in sequence by peptide linkages.


A glycophytoceramide that consists of phytosphingosine having a 6-acetamido-6-deoxy-alpha-D-galactosyl attached at the O-1 position via a glycosidic linkage and a (Z)-tetracos-15-enoyl group attached to the nitrogen.


D-alanine derivative

A non-proteinogenic amino acid derivative resulting from reaction of D-alanine at the amino group or the carboxy group, or from the replacement of any hydrogen of D-alanine by a heteroatom.


carboxamide

An amide of a carboxylic acid, having the structure RC(=O)NR2. The term is used as a suffix in systematic name formation to denote the -C(=O)NH2 group including its carbon atom.


meglumine

A  hexosamine that is D-glucitol in which the hydroxy group at position 1 is substituted by the nitrogen of a methylamino group. A crystalline base, it is used in preparing salts of certain acids for use as diagnostic radiopaque media, while its antimonate is used as an antiprotozoal in the treatment of leishmaniasis.


An N-acyl-1-O-beta-D-glucosyl-15-methylhexadecasphing-4-enine in which the acyl group has 21 carbons and 4 double bonds and is 2-hydroxylated.


An N-acyl-D-galactosylsphingosine in which the ceramide N-acyl group is composed of 24 carbons and 2 double bonds.


nucleoside analogue

An analogue of a nucleoside, being an N-glycosyl compound in which the nitrogen-containing moiety is a modified nucleotide base. They are commonly used as antiviral products to prevent viral replication in infected cells.


An aminodisaccharide that is 2-acetamido-2-deoxy-beta-D-glucopyranose in which the hydroxy group at position 6 has been glycosylated by an alpha-D-mannopyranosyl group.


An N-acyl-1-O-beta-D-glucosyl-15-methylhexadecasphing-4-enine in which the acyl group has 18 carbons and 2 double bonds.


azine

An organonitrogen compound of general structure RCH=N-N=CHR or RR'C=N-N=CRR'.


An L-threonine derivative in which L-threonine is linked via its nitrogen to C-6 of the non-reducing-end galactose residue of 3-O-acetyl-alpha-D-galacto-hexodialdo-1,5-pyranosyl-(1->3)-N-acetyl-acetamido-2-deoxy-beta-D-galactosamine; an important threonine-containing epitope of the Proteus penneri O-specific polysaccharide.


An amino trisaccharide consisting of a 2-acetamido-2-deoxy-beta-D-glucopyranose residue and two alpha-D-mannopyranose residues joined in sequence by (1->6) glycosidic bonds.


N-methyl-amino acid

An amino acid derivative in which at least one of the hydrogens of the amino group has been replaced by a methyl group.


GlyTouCan G03574QJ

A composition-only glycan consisting of six hexosyl groups, three 2-acetaminohexosyl groups and one 6-deoxyhexosyl group (identities and connectivity unknown). Composition: Hex6 HexNAc3 dHex1.


A dicarboxylic acid diamide comprising suberic (octanedioic) acid coupled to aniline and 1,2-diaminobenzene.


phosphoramide

A compound in which one or more of the OH groups of phosphoric acid have been replaced with an amino or substituted amino group. The term is commonly confined to the phosphoric triamides, P(=O)(NR2)3, since replacement of one or two OH groups produces phosphoramidic acids: P(=O)(OH)(NR2)2 , P(=O)(OH)2(NR2).


hydrazone

Compounds having the structure R2C=NNR2, formally derived from aldehydes or ketones by replacing =O by =NNH2 (or substituted analogues).


A glycophytoceramide having a 6-O-(1-naphthylcarbamoyl)-alpha-D-galactopyranosyl residue at the O-1 position and a hexacosanoyl group attached to the nitrogen.


B vitamin

Any member of the group of eight water-soluble vitamins originally thought to be a single compound (vitamin B) that play important roles in cell metabolism. The group comprises of vitamin B1, B2, B3, B5, B6, B7, B9, and B12 (Around 20 other compounds were once thought to be B vitamins but are no longer classified as such).


A beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-N-acylsphingosine in which the acyl group specified is octadecanoyl.


cyanates

Salts and esters of cyanic acid, HOC#N; compounds carrying the cyanate functional group -O-C#N.


Lys-Thr-Trp-Gly-Lys-Asn-Leu-Val-Phe

An oligopeptide composed of L-lysine, L-threonine, L-tryptophan, glycine, L-asparagine, L-leucine, L-valine and L-phenylalanine joined in sequence by peptide linkages; corresponds to the sequence in the yellow feverspecific peptide epitope K9F.


N,N'-dimethylurea

A member of the class of ureas that is urea substituted by methyl groups at positions 1 and 3.


cyanine conjugate

A cyanine dye connected via a linker to a hapten.


L-cysteine-S-dioxide

A cysteine derivative consiting of L-cysteine carrying two S-oxy-substituents.


An N-acyl-1-O-beta-D-glucosyl-15-methylhexadecasphing-4-enine in which the acyl group has 27 carbons and 0 double bonds.


An amino trisaccharide consisting of D-mannopyranose in which the hydroxy groups at positions 3 and 4 have been converted into the corresponding alpha-D-mannopyranosyl and 2-acetamino-2-deoxy-beta-D-glucopyranosyl derivatives, respectively.


N(beta)-acetylstreptothricin F(2+)

The N(beta)-acetyl derivative of streptothricin F(3+); major microspecies at pH 7.3.


ristocetin

A heterodetic cyclic peptide  that is produced by species of Amycolatopsis and Nocardia.


name: 5-carbamoyl-4-methyl-2-[[(3-nitrophenyl)-oxomethyl]amino]-3-thiophenecarboxylic acid methyl ester


allopurinol riboside

A nucleoside analogue that is allopurinol with a beta-D-ribofuranosyl moiety at the 1-position.


arcaine

A guanidine derivative consisting of butane having guanidino groups at the 1- and 4-positions.


A beta-D-galactosyl-(1<->1')-N-acylsphinganine in which the acyl group specified is hexacosanoyl.


An amino trisaccharide consisting of 2-acetamido-2-deoxy-alpha-D-glucopyranose, beta-D-galactopyranose and 2-acetamido-2-deoxy-D-glucopyranose residues joined in sequence by (1->4) glycosidic bonds.


A sphinganine derivative having a beta-D-glucosyl group at the 1-position and an octadecanoyl group attached to the nitrogen.


A glycononaosylceramide having beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-[alpha-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->6)]-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc as the glycononaosyl component.


A glycosylceramide in which the oligoglycosyl component can be any oligoglycosyl-(1->4)-beta-D-glucosyl residue.


A ceramide obtained by formal condensation of the carboxy group of pentacosanoic acid with the amino group of 14-methylhexadecasphingosine. It is a metabolite of the nematode Caenorhabditis elegans.


A ceramide obtained by formal condensation of the carboxy group of tricosenoic acid with the amino group of 14-methylhexadecasphingosine. It is a metabolite of the nematode Caenorhabditis elegans.


name: 2-[[(4-methyl-5-thieno[3,2-b]pyrrolyl)-oxomethyl]amino]benzoic acid methyl ester


nitroalkane

A nitrohydrocarbon that is an alkane in which one of the hydrogens has been replaced by a nitro group.


TAFAMIDIS MEGLUMINE

An organoammonium salt obtained by combining tafamidis with one molar equivalent of 1-deoxy-1-(methylamino)-D-glucitol. Used for the amelioration of transthyretin-related hereditary amyloidosis.


An amino trisaccharide that is 2-acetamido-2-deoxy-alpha-D-glucopyranose in which the hydroxy groups at positions 4 and 6 have been converted into the corresponding 2-acetamido-2-deoxy-alpha-D-glucopyranosy and beta-L-fucopyranosyl derivatives, respectively.


A sialopentaosylceramide consisting of alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-beta-D-GalNAc-(1->4)-[alpha-Neu5Ac-(2->3)]-beta-D-Gal-(1->4)-beta-D-Glucosyl unit attached to the Cer(d18:1/20:0).


An amino trisaccharide that is 2-acetamido-2-deoxy-beta-D-glucopyranose in which the hydroxy groups at positions 4 and 6 have been converted into the corresponding 2-acetamido-2-deoxy-beta-D-glucopyranosyl and beta-L-fucopyranosyl derivatives, respectively.


A phenylenediamine in which the two amino groups are ortho to each other.


mixed diacylamine

Any imide in which the acyl substituents are any two from carboacyl, sulfonyl and phosphoryl


GlyTouCan G00390GQ

A composition-only glycan consisting of two hexosyl groups, two acetaminohexosyl groups and two N-acetyl-neuraminic acid groups (identities and connectivity unknown). Composition:  Hex2 HexNAc2 NeuAc2.


CHRYSOGESIDE E

A glucosylceramide isolated from Penicillium chrysogenum.


imine

Compounds having the structure RN=CR2 (R = H, hydrocarbyl). Thus analogues of aldehydes or ketones, having NR doubly bonded to carbon; aldimines have the structure RCH=NR, ketimines have the structure R'2C=NR (where R' is not H). Imines include azomethines and Schiff bases. Imine is used as a suffix in systematic nomenclature to denote the C=NH group excluding the carbon atom.


An N-acyl-1-O-beta-D-glucosyl-15-methylhexadecasphing-4-enine in which the acyl group has 23 carbons and 0 double bonds.


An amino disaccharide consisting of alpha-D-mannopyranose and 2-acetamido-2-deoxy-alpha-D-glucopyranose residues joined in sequence by a (1->4) glycosidic bond.


A C20 dihydroceramide in which the ceramide N-acyl group is specified as 2-hydroxytricontanoyl.


An amino disaccharide consisting of beta-L-fucopyranose and 2-acetamido-2-deoxy-beta-D-glucopyranose residues joined in sequence by a (1->6) glycosidic bond.


name: 2,3-dihydro-1,4-dioxin-5-carboxylic acid [2-(4-cyanoanilino)-2-oxoethyl] ester


An amino disaccharide that is 2-acetamido-2-deoxy-beta-D-glucopyranose in which the hydroxy group at position 6 has been converted into the corresponding beta-D-glucopyranoside.


N(4)-acetyl-L-2,4-diaminobutyric acid

The N(4)-acetyl derivative of L-2,4-diaminobutyric acid


An amino trisaccharide consisting of beta-D-galactopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose and D-galactopyranose residues joined in sequence by (1->3) glycosidic bonds.


name: spermidine hydroxycinnamic acid conjugate

description: A carboxamide derivative between one or more of the nitrogens of spermidine and a hydroxycinnamic acid.


A glycophytoceramide having an 4-deoxy-alpha-D-xylo-hexopyranosyl residue at the O-1 position and an hexacosanoyl group attached to the nitrogen.


A synthetic tetrapeptide composed of the non-natural Ac-Cha, Gpg, Tic and Nle-NHCH2CH2Ph residues coupled in sequence.


A glycophytoceramide having a 4-O-(4-phenylbutyl)-alpha-D-galactosyl residue at the O-1 position and a hexacosanoyl group attached to the nitrogen. One of a series of an extensive set of 4"-O-alkylated alpha-GalCer analogues evaluated (PMID:30556652) as invariant natural killer T-cell (iNKT) antigens.


An amino trisaccharide consisting of alpha-D-mannopyranose, beta-D-mannopyranose and 2-acetamido-2-deoxy-D-glucopyranose residues joined in sequence by (1->6) and (1->4) glycosidic bonds.


A glycophytoceramide having a 4-O-allyl-alpha-D-galactosyl residue at the O-1 position and a hexacosanoyl group attached to the nitrogen. One of a series of an extensive set of 4"-O-alkylated alpha-GalCer analogues evaluated (PMID:30556652) as invariant natural killer T-cell (iNKT) antigens.


Leu-Ser-Ser-Tyr

A tetrapeptide composed of L-leucine, two L-serine units and L-tyrosine joined in sequence by peptide linkages.


An aminotrisaccharide that is N-acetyllactosamine in which the hydroxy group at position 6 has been converted into the corresponding alpha-L-fucopyranosyl derivative.


A benzenedicarboxamide in which one nitrogen forms the beta-nitogen of beta-alanine and the other is the N of 2,3,3a,4,7,7a-hexahydro-1H-isoindole.


Any ceramide having 15-methylhexadecasphing-4-enine as the sphingoid component.


vasopressin

The predominant form of mammalian vasopressin (antidiuretic hormone). It is a nonapeptide containing an arginine at residue 8 and two disulfide-linked cysteines at residues of 1 and 6.


GlyTouCan G03930BU

A composition-only glycan consisting of four hexosyl groups, three acetaminohexosyl groups and three 6-deoxyhexosyl groups (identities and connectivity unknown). Composition: Hex4 HexNAc3 dHex3.


vitamin B9

Any B-vitamin that exhibits biological activity against vitamin B9 deficiency. Vitamin B9 refers to the many forms of folic acid and its derivatives, including tetrahydrofolic acid (the active form), methyltetrahydrofolate (the primary form found in blood), methenyltetrahydrofolate, folinic acid amongst others. They are present in abundance in green leafy vegetables, citrus fruits, and animal products. Lack of vitamin B9 leads to anemia, a condition in which the body cannot produce sufficient number of red blood cells. Symptoms of vitamin B9 deficiency include fatigue, muscle weakness, and pale skin.


An N-acyl-1-O-beta-D-glucosyl-15-methylhexadecasphing-4-enine in which the acyl group has 19 carbons and 0 double bonds and is 2-hydroxylated.


Leu-Ser-Glu-Thr-Thr-D-Leu

A six-membered oligopeptide comprising L-leucine, L-serine, L-glutamic acid, L-threonine, L-threonine and D-leucine residues coupled in sequence.


A beta-D-Gal-(1->3)-D-GalNAc having beta-configuration at the reducing end anomeric centre.


cabergoline

An N-acylurea that is (8R)-ergoline-8-carboxamide in which the hydrogen attached to the piperidine nitrogen (position 6) is substituted by an allyl group and the hydrogens attached to the carboxamide nitrogen are substituted by a 3-(dimethylamino)propyl group and an N-ethylcarbamoyl group. A dopamine D2 receptor agonist, cabergoline is used in the management of Parkinson's disease and of disorders associated with hyperprolactinaemia.


A glycophytoceramide having an alpha-D-galactopyranosyl residue at the O-1 position and an 11-(4-methoxyphenyl)undecanoyl group attached to the nitrogen.


An oligopeptide composed of the tripeptide unit beta-alanyl-L-leucyl-L-alanyl which is attached via an amide bond to the amino terminus of the pseudopeptide fragment 3-({[N-(2-aminoethyl)-N-(indol-3-ylacetyl)glycyl]amino}methyl)benzoyl, which is in turn attached via an amide bond to the amino terminus of the tripeptide unit L-leucyl-L-threonyl-L-valine.


An amino disaccharide consisting of two 2-acetamido-2-deoxy-beta-D-glucopyranose residues joined by a (1->3) glycosidic bond.


An amino trisaccharide that is 2-acetamido-2-deoxy-D-glcopyranose in which the hydroxy groups at positions 4 and 6 have each been converted into the corresponding alpha-L-fucopyranosyl derivative.


fragin zwitterion

A diazeniumdiolate natural product found in Burkholderia cenocepacia with an antifungal activity.


An alanine derivative consisting of alanine having a 6-oxo-6,9-dihydro-1H-purin-2-yl group attached to the amino function.


A glycophytoceramide having a 4-O-(3-phenylpropyl)-alpha-D-galactosyl residue at the O-1 position and a hexacosanoyl group attached to the nitrogen. One of a series of an extensive set of 4"-O-alkylated alpha-GalCer analogues evaluated (PMID:30556652) as invariant natural killer T-cell (iNKT) antigens.


ganglioside GM1

A sialotetraosylceramide consisting of a branched pentasaccharide made up from one sialyl residue, two galactose residues, one N-acetylgalactosamine residue and a glucose residue at the reducing end attached to N-stearoylsphingosine via a beta-linkage.


A sialohexaosylceramide consisting of a linear heptasaccharide made up from one sialyl residue, three galactose residues, two N-acetylglucosamine residues and one glucose residue, which at the reducing end is attached to the ceramide portion via a beta-linkage.


Asp-Leu-Thr-Asp

A tetrapeptide composed of L-aspartic acid, L-leucine, L-threonine and L-aspartic acid joined in sequence by peptide linkages.


glyoxamides

Compounds with the structure R2NC(=O)C(=O)H.


An amino disaccharide consisting of alpha-D-mannopyranose and 2-acetamido-2-deoxy-D-glucopyranose residues joined in sequence by a (1->6) glycosidic bond.


D-asparagine derivative

A non-proteinogenic amino acid derivative resulting from reaction of D-asparagine at the amino group, the carboxy group, or the carboxamide, or from the replacement of any hydrogen of D-asparagine by a heteroatom.


A D-galactosyl-N-acylsphingosine in which the galactosyl moiety is attached by a beta-linkage at the anomeric position and in which the N-acyl moiety bears a hydroxy group alpha- to the carboxamide group


A fifteen-membered glycopeptide comprising glycyl, 2-aminoindane-2-formyl, alanyl, glycyl, phenylalanyl, (5R)-5-(beta-D-galactopyranosyloxy)lysyl, glycyl. alpha-glutamyl, glutaminyl, glycyl, prolyl, lysyl, glycyl, alpha-glutamyl and threonine residues coupled in sequence.


A galactosylceramide obtained by formal condensation of the carboxy group of icosanoic acid with the amino group of beta-D-galactosyl-(1<->1')-(4E,14Z)-sphingadienine.


A beta-D-glucosylceramide in which a beta-D-glucosyl residue attached to the primary hydroxyl group of N-pentacosanoyl-14-methylhexadecasphingosine. It is a metabolite of the nematode Caenorhabditis elegans.


Asn-Leu-Leu-Ser

A tetrapeptide composed of L-asparagine, two L-leucine units, and L-serine joined in sequence by peptide linkages.


A C-glycosyl compound that is L-tryptophan in which the hydrogen at position 2 on the indole protion has been replaced by an alpha-mannosyl residue.


The E (anti) isomer of testosterone 3-(O-carboxymethyl)oxime.


trans-azoxybenzene

An azoxybenzene with a trans-configuration.


sphingolipid

Sphingolipids are a complex family of compounds that share a common structural feature, a sphingoid base backbone.


A hexosyl-(1<->1')-N-acylsphinganine in which the hexosyl component is specified as  beta-D-glucosyl.


An amino tetrasaccharide consisting of a beta-D-xylofuranose residue, a beta-D-mannopyranose residue and two 2-acetamido-2-deoxy-beta-D-glucopyranose residues joined in sequence by (1->2), (1->4) and (1->4) glycosidic bonds.


A  dicarboxylic acid diamide that is a derivative of butyl(hydroxy)malonic acid in which one carboxy group has formed a hydrazide with 1,2-diphenylhydrazine and the other an amide with 6-aminohexanoic acid.


An aci-nitro compound resulting from the formal tautomerisation of the nitro group of (2-nitroethyl)benzene.


A 1-O-acyl-N-acylsphingosine in which the N- and O-acyl groups are specified as acetyl and palmitoyl (hexadecanoyl) respectively.


Amino acid amide with 2,6-dimethylanilino and 2-aminobutanoyl components.


ISOPROTURON

A member of the class of phenylureas that is 1,1-dimethylurea substituted by a p-cumenyl group at position 3. A selective, systemic herbicide used to control annual grasses and broadleaf weeds in cereals, its use within the EU has been banned after September 2017 on the grounds of potential groundwater contamination and risks to aquatic life; there have also been concerns about its endocrine-disrupting properties.


A dihydroceramide in which the ceramide N-acyl group is specified as 2-hydroxyoctadecanoyl.


name: 3-[(4-chlorophenyl)sulfonylamino]propanoic acid [2-(2-furanylmethylamino)-2-oxoethyl] ester


name: 2-(4-nitrophenyl)-4-thiazolecarboxylic acid ethyl ester


name: 2-[2-[[2-[(5-cyclopropyl-4-methyl-1,2,4-triazol-3-yl)thio]-1-oxoethyl]amino]-4-thiazolyl]acetic acid ethyl ester


alpha-galactosylceramide

A galactosylceramide in which the galactosyl residue has alpha anomeric conofiguration.


ethylammonium pivalate

An organoammonium salt resulting from the mixing of equimolar amounts of pivalic acid and ethylamine.


phosphine

Phosphane (PH3) and compounds derived from it by substituting one, two or three hydrogen atoms by hydrocarbyl groups: RPH2, R2PH, R3P (R =/= H) are called primary, secondary and tertiary phosphines, respectively. A specific phosphine is preferably named as a substituted phosphane.


glycodihydroceramide

A dihydroceramide having at least one glycosyl group attached to either of its hydroxy groups.


A phenylenediamine in which the amino functions are at positions 1 and 4 of the benzene nucleus.


AcGly-Ser(O-L-alpha-D-Hep)-Gly-Leu

A derivatised tetrapeptide in which a parent tetrapeptide comprising glycine, L-serine, glycine and L-leucine residues coupled in sequence, has its terminal glycine residue  acetylated on nitrogen and its serine residue L-glycero-alpha-D-heptosylated on oxygen.


cyclo(Leu-Ser-Glu-Thr-Lys-Thr-D-Leu)

A seven-membered homodetic cyclic peptide comprising the sequence L-leucine, L-serine, L-alpha-glutamic acid, L-threonine, L-lysine, L-threonine, D-leucine.


An amino tetrasaccharide that is beta-D-Galp-beta-D-GalpNAc-D-Glcp in which the acetaminogalactosyl group has undergone formal glycosylation at position 6 by a beta-D-acetaminogalactopyranosyl group.


Pro-Val-Val-Pro

A tetrapeptide composed of L-proline, two L-valine units and L-proline joined in sequence by peptide linkages.


amide fungicide

Compounds that contain an amide group as a key feature of their structure and which have been used as fungicides.


name: 4-[3-(4-methoxyanilino)-3-oxopropyl]-1-piperazinecarboxylic acid ethyl ester


N-icosenoylsphinganine

A dihydroceramide in which the acyl group contains 20 carbons and 1 double bond of unknown position.


felypressin

A synthetic nonapeptide comprising cysteinyl, phenylalanyl, phenylalanyl, glutaminyl, asparaginyl, cysteinyl, prolyl, lysyl, and glycinamide residues in sequence, with a disulfide bridge joining the two cysteine residues. Its antidiuretic effects are less than those of vasopressin. It is used as a vasoconstrictor in local anaesthetic injections for dental use, and is an ingredient of preparations that have been used for treatment of pain and inflammation of the mouth.


An N-acyl-1-O-beta-D-glucosyl-15-methylhexadecasphing-4-enine in which the acyl group has 25 carbons and 0 double bonds and is 2-hydroxylated.


Leu-Ser-Glu-Thr-Glu-Thr-Lys(Ac)-D-Leu

An eight-membered oligopeptide comprising L-leucine, L-serine, L-glutamic acid, L-threonine, L-glutamic acid, L-threonine, N(6)-acetyl-L-lysine and D-leucine residues coupled in sequence.


An N-acetyl-beta-D-galactosaminyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosylceramide in which the ceramide N-acyl group is specified as stearoyl.


An N-acyl-15-methylhexadecasphing-4-enine in which the acyl group has 20 carbons and 0 double bonds and is 2-hydroxylated.


An amino disaccharide consisting of beta-D-galactopyranose and 2-acetamido-2-deoxy-alpha-D-glucopyranose residues joined in sequence by a (1->6) glycosidic bond.


An amino trisaccharide that is 2-acetamido-2-deoxy-alpha-D-galactopyranose in which the hydroxy groups at positions 3 and 6 have been converted into the corresponding beta-D-galactopyranosyl derivatives.


name: 2-(2-methoxy-2-oxoethyl)-3-oxo-1-piperazinecarboxylic acid tert-butyl ester


An N-acyl-1-O-beta-D-glucosyl-15-methylhexadecasphing-4-enine in which the acyl group has 28 carbons and 0 double bonds.


asparagine derivative

An amino acid derivative resulting from reaction of asparagine at the amino group, the carboxy group, or the carboxamide, or from the replacement of any hydrogen of asparagine by a heteroatom. The definition normally excludes peptides containing asparagine residues.


An isocyanate that is 1,1,3,3-tetramethylcyclohexane in which one of the methyl groups carries a isocyanato substituent.


organonitrogen compound

Any heteroorganic entity containing at least one carbon-nitrogen bond.


An amino tetrasaccharide consisting of beta-D-galactopyranose, 2-acetamido-2-deoxy-beta-D-galactopyranos, beta-D-galactopyranose and beta-D-glucopyranose residues joined in sequence by (1->4) glycosidic bonds.


An N-acyl-1-O-beta-D-glucosyl-15-methylhexadecasphing-4-enine in which the acyl group has 19 carbons and 2 double bonds.


name: 6-methyl-2-[[2-(4-morpholinyl)-1-oxoethyl]amino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylic acid methyl ester


A synthetic tetrapeptide comprising Ac-Cha, Arg, Disc and Met-NH2 residues coupled in sequence.


A heterodetic cyclic peptide consisting of somatostatin in which the amino terminus has been acylated by the fourteen membered peptide Ser-Ala-Asn-Ser-Asn-Pro-Ala-Met-Ala-Pro-Arg-Glu-Arg-Lys.


A synthetic 17-mer oligopeptide derived from the Ara h2 protein comprising N-acetyl-L-alpha-glutamyl, L-arginyl, L-asparaginyl, L-prolyl, L-tyrosyl, L-seryl, L-prolyl, L-seryl, L-glutaminyl, L-asparaginyl, L-prolyl, L-tyrosyl, L-seryl, L-prolyl, L-seryl, L-glutaminyl and L-lysinamide residues coupled in sequence.


phosphocerebroside

A ceramide that consists of a cerebroside carrying one or more phosphate or alkyl phosphate substituents.


A member of the class of phenylhydrazines that is  phenylhydrazine substituted at the 4-position by a nitro group.


A glycophytoceramide having an alpha-D-galactopyranosyl residue at the O-1 position and a 9-phenylnonanoyl group attached to the nitrogen.


name: 2-[(2-acetamido-1-oxoethyl)amino]-3-phenylpropanoic acid ethyl ester


Ala-Leu-Ala-Pro

A tetrapeptide composed of L-alanine, L-leucine, L-alanine, and L-proline joined in sequence by peptide linkages.


N(alpha)-t-butoxycarbonyl-L-asparagine

The N(alpha)-t-butoxycarbonyl derivative of L-asparagine


A secondary amino compound consisting of two molecules of tacrine that are linked together through their exocyclic amino groups by a heptane-1,7-diyl chain. Bis(7)-tacrine is an acetylcholinesterase (AChE)inhibitor (IC50 0.40 nM, >1,000 times more potent than tacrine). It has also been found to protect against H2O2 -induced apoptosis in rat pheochromocytoma cells.


A sialopentaosylceramide consisting of a alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-beta-D-GalNAc-(1->4)-[alpha-Neu5Ac-(2->3)]-beta-D-Gal-(1->4)-beta-D-Glucosyl unit attached to a Cer(d18:1/24:0).


A fifteen-membered glycopeptide comprising glycyl, cyclohexylglycyl, alanyl, glycyl, 4-pyridylalanyl, (5R)-5-(beta-D-galactopyranosyloxy)lysyl, glycyl. alpha-glutamyl, glutaminyl, glycyl, prolyl, lysyl, glycyl, alpha-glutamyl and threonine residues coupled in sequence.


N-carbamoylsarcosine

The N-carbamoyl derivative of sarcosine.


An amino trisacharide that is beta-D-galacopyranose in which the hydroxy groups at positions 3 and 4 have each been converted into the corresponding 2-acetamido-2-deoxy-beta-D-glucopyranosyl derivative.


An N-acyl-15-methylhexadecasphing-4-enine in which the acyl group has 28 carbons and 0 double bonds and is 2-hydroxylated.


A cerebroside in which the ceramide N-acyl group is specified as hexadecanoyl.


An oligopeptide composed of L-alanine, L-arginine, glycine, L-tyrosine, L-serine, L-serine, L-phenylalanine, L-arginine, L-tyrosine, L-trytophan, L-phenylalanine and L-phenylalanine joined in sequence by peptide linkages.


sialodecaosylceramide

A ganglioside in which the oligosaccharide portion is composed of a decasaccharide, to which one or more sialic acid residues are attached.


name: carbamimidothioic acid 2-[4-[(4-nitrophenyl)methoxy]phenyl]ethyl ester


pantothenic acids

A class of amides formed from pantoic acid and beta-alanine and its derivatives.


4-nitrophenyl beta-lactoside

A disaccharide derivative that is beta-lactose in which the anomeric hydroxy hydrogen is replaced by a 4-nitrophenyl group.


D-galactosyl-N-hexadecanoylsphinganine

A  glycodihydroceramide that is a sphinganine derivative having a D-galactosyl group at the 1-position and a hexadecanoyl group attached to the nitrogen.


An L-tyrosine derivative in which the phenolic hydrogen is replaced by a dimethylallyl group.


A ceramide in which the sphingoid component is specified as (4E,8Z)-sphinga-4,8-dienine.


D-tyrosine derivative

A non-proteinogenic amino acid derivative resulting from reaction of D-tyrosine at the amino group or the carboxy group, or from the replacement of any hydrogen of D-tyrosine by a heteroatom.


glycodiaosylceramide

An oligoglycosylceramide in which the oligoglycosyl component is derived from the cyclic form of a disaccharide (or derivative).


A phytoceramide in which the ceramide N-acyl group is specified as 2-hydroxytriacontanoyl.


An amino trisaccharide consisting of a beta-D-mannopyranose residue and two 2-acetamido-2-deoxy-alpha-D-glucopyranose residues joined in sequence by (1->4) glycosidic bonds.


name: 3-methyl-5-[[1-oxo-2-(2-pyridinylmethylamino)ethyl]amino]thiophene-2,4-dicarboxylic acid diethyl ester


An aminopentasaccharide that is 2-acetamido-D-alactitol which has been glycosylated at positions 3 and 6 by 2-acetamido-beta-D-glucopyranosyl and alpha-L-fucosyl-(1->3)-[beta-D-galactopyranosyl-(1->4)]-2-acetamido-beta-D-glucopyranosyl groups, respectively.


A sialotriaosylceramide consisting of beta-D-GalNAc-(1->4)-[alpha-Neu5Ac-(2->3)]-beta-D-Gal-(1->4)-beta-D-Glc attached to the primary hydroxy function of ceramide(d18:1/18:0).


A sialotetraosylceramide consisting of a branched octasaccharide made up from four sialyl residues, two galactose residues, one N-acetylglucosamine residue and a glucose residue at the reducing end attached to the ceramide portion via a beta-linkage.


N-glycosyl compound

A glycosyl compound arising formally from the elimination of water from a glycosidic hydroxy group and an H atom bound to a nitrogen atom, thus creating a C-N bond.


tricoumaroyl spermidine

A spermidine hydroxycinnamic acid conjugate in which each nitrogen of spermidine has entered into amide bond formation with a molecule of 4-coumaric acid.


Leu-Ser-Glu-Thr-Tyr-Thr-Lys-D-Leu

An eight-membered oligopeptide comprising L-leucine, L-serine, L-glutamic acid, L-threonine, L-tyrosine, L-threonine, L-lysine and D-leucine residues coupled in sequence.


4-nitrophenyl beta-D-glucoside

A beta-D-glucoside that is beta-D-glucopyranose in which the anomeric hydroxy hydrogen is replaced by a 4-nitrophenyl group.


hexamidine

A polyether that is the bis(4-guanidinophenyl) ether of hexane-1,6-diol.


name: 2-(2,6-dichlorophenyl)acetic acid [2-oxo-2-[4-(trifluoromethoxy)anilino]ethyl] ester


A sialotetraosylceramide consisting of a branched heptasaccharide made up from three sialyl residues, two galactose residues, one N-acetylglucosamine residue and a glucose residue at the reducing end attached to the ceramide portion via a beta-linkage.


D-threonine derivative

A non-proteinogenic amino acid derivative resulting from reaction of D-threonine  at the amino group or the carboxy group, or from the replacement of any hydrogen of D-threonine  by a heteroatom.


benzylpenicilloyl-octa-L-lysine

An oligopeptide that is octa-L-lysine (Lys-Lys-Lys-Lys-Lys-Lys-Lys-Lys) in which each lysine residue is substituted on the epsilon-nitrogen by a benzylpenicilloyl group; used in skin-testing for penicillin allergy.


A glycophytoceramide having an alpha-D-galactopyranosyl residue at the O-1 position and a 6-(4-trifluoromethyl)hexanoyl group attached to the nitrogen.


3-sulfo propionyl L-cysteine(1-)

Major microspecies at pH 7.3.


nitrogen mustard

Compounds having two beta-haloalkyl groups bound to a nitrogen atom, as in (X-CH2-CH2)2NR.


A sialopentaosylceramide having alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-[alpha-L-Fuc-(1->4)]-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc as the sialopentaosyl component.


A glycophytoceramide having a 6-O-(4-pyridylcarbamoyl)-alpha-D-galactopyranosyl residue at the O-1 position and an hexacosanoyl group attached to the nitrogen.


A glycophytoceramide having an alpha-D-galactopyranosyl residue at the O-1 position and a dodecanoyl group attached to the nitrogen.


L-selenocysteine derivative

A proteinogenic amino acid derivative resulting from reaction of L-selenocysteine at the amino group or the carboxy group, or from the replacement of any hydrogen of L-selenocysteine by a heteroatom.


GlyTouCan G06853GH

A composition-only glycan consisting of four hexosyl groups, seven acetaminohexosyl groups and one 6-deoxyhexosyl group (identities and connectivity unknown). Composition: Hex4 HexNAc7 dHex1.


An amino trisaccharide that is 2-acetamido-2-deoxy-beta-D-galactopyranose in which the hydroxy groups at positions 3 and 6 have been converted into the corresponding beta-D-galactopyranosyl and 2-acetamido-2-deoxy-beta-D-glucopyransoyl derivatives, respectively.


carbodiimide

Any organonitrogen compound that consists of two primary amino groups joined to a central carbon atom via N=C linkages.


malonamide

A dicarboxylic acid diamide that is malonic acid in which both carboxy groups have been replaced by carbamoyl groups.


A D-galactosyl-N-acylsphingosine in which the ceramide N-acyl group is dodecanoyl.


A branched glycononaosylceramide having beta-D-galactosyl-(1->4)-[alpha-L-fucosyl-(1->3)]-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucose as the glycononaosyl portion.


Ac-Gln-D-Phe-His-D-Pro-betaAla-betaAla

An oligopeptide comprising N(2)-acetyl-L-glutamine, D-phenylalanine, L-histidine, D-proline and two beta-alanine residues coupled in sequence.


An amino trisaccharide consisting of 2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-galactopyranose and 2-acetamido-2-deoxy-D-glucopyranose residues joined in sequence by (1->3) glycosidic bonds.


methacetin

A member of the class of acetamides that is paracetamol in which the hydrogen of phenolic hydroxy group has been replaced by a methyl group.


A ceramide that is the N-(2-hydroxyhexadecanoyl) derivative of eicosasphinganine.


A glycophytoceramide having a 6-O-[(4-chlorophenyl)carbamoyl]-alpha-D-galactopyranosyl residue at the O-1 position and an hexacosanoyl group attached to the nitrogen.


isocyanide

The isomer HN(+)#C(-) of hydrocyanic acid, HC#N, and its hydrocarbyl derivatives RNC (RN(+)#C(-)).


sialooctaosylceramide

A ganglioside in which the oligosaccharide portion is composed of an octasaccharide, to which one or more sialic acid residues are attached.


A glycodihydroceramide having alpha-D-galactosyl component and the ceramide N-acyl group specified as tetradecanoyl.


GlyTouCan G01666TL

A composition-only glycan consisting of one acetaminohexosyl group and two 6-deoxyhexosyl groups (identities and connectivity unknown). Composition: HexNAc1 dHex2.


A polymer composed of repeating 4-carbamoyl-6-(hexylcarbamoyl)isophthalic acid units.


hydrazide

Compounds derived from oxoacids RkE(=O)l(OH)m (l =/= 0) by replacing -OH  by -NRNR2 (R groups are commonly H). (IUPAC).


A dihydroceramide in which the ceramide N-acyl group is specified as 2-hydroxytriacontanoyl.


N-tricosenoyl-D-galactosylsphingosine

An N-acyl-D-galactosylsphingosine in which the ceramide N-acyl group is composed of 23 carbons and 1 double bond.


An amino disaccharide consisting of alpha-D-mannopyranose and 2-acetamido-2-deoxy-D-glucopyranose residues joined in sequence by a (1->3) glycosidic bond.


glycododecaosylceramide

Any oligoglycosylceramide where the oligoglycoside component is a  dodecasaccharide.


A ganglioside derivative that is gangliosde GM1 in which the sialic acid residue contains CH2OH instead of COOH.


A glycotriaosylceramide having alpha-D-galactosyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosyl as the glycotriaosyl component attached to the Cer(d18:1/23:0).


A synthetic sphingoid in which C16 phytosphingosine is substituted at O-1, C-16 and N with respectively an alpha-D-galactopyranosyl group, a phenyl group and an octanoyl group.


A fifteen-membered glycopeptide comprising glycyl, homoleucyl, alanyl, glycyl, 3-(1,3-thiazol-4-yl)alanyl, (5R)-5-(beta-D-galactopyranosyloxy)lysyl, glycyl. alpha-glutamyl, glutaminyl, glycyl, prolyl, lysyl, glycyl, alpha-glutamyl and threonine residues coupled in sequence.


An amino disaccharide consisting of beta-D-glucopyranose and 2-acetamido-2-deoxy-beta-D-glucopyranose residues joined in sequence by a (1->4) glycosidic bond.


semicarbazone

A hydrazone resulting from the formal condensation of an aldehyde or ketone with the non-acylated nitrogen of semicarbazide or its substituted derivatives.


A beta-D-glucosylceramide in which a beta-D-glucosyl residue attached to the primary hydroxyl group of N-tricosanoyl-15-methylhexadecasphinganine. It is a metabolite of the nematode Caenorhabditis elegans.


A neutral glycosphingolipid comprising a tetrasaccharide unit, alpha-D-Man-(1->2)-alpha-D-Gal-(1->6)-alpha-D-GlcN-(1->4)-alpha-D-GlcA, attached to a 12-(2-hexylcyclopropyl)-3-hydroxy-2-{[(2S)-2-hydroxytetradecanoyl]amino}dodecyl lipid group.


A cationic C1 cyanine dye having benzothiazolium-2-yl and quinolinium-4-yl substituents.


A sialotetraosylceramide consisting of a linear pentasaccharide made up from a sialyl residue, two galactose residues, one N-acetylglucosamine residue and a glucose residue at the reducing end attached to the ceramide portion via a beta-linkage.


N,N'-(p-xylylidene)bis(aminoguanidine)

A guanidine derivative comprised of two carbamimidamido (guanidino) groups, each linked via one of their amino nitrogens to the imino nitrogens of 1,4-phenylenedimethanimine.


L-isoglutamine

An isoglutamine that has L-configuration.


glycosyl-N-hexadecanoylsphinganine

Any glycosylceramide in which the acyl group specified is hexadecanoyl (palmitoyl).


A ceramide obtained by formal condensation of the carboxy group of icosanoic acid with the amino group of 14-methylhexadecasphinganine. It is a metabolite of the nematode Caenorhabditis elegans.


L-erythro-N-dodecanoylsphingosine

A sphingolipid that is the N-dodecanoyl (lauroyl) derivative of L-erythro-sphingosine.


Disperse Red 1

An azo dye with a structure consisting of nitrobenzene substituted on the 4-position of the phenyl group with a 4-[N-ethyl-N-(2-hydroxyethyl)]phenylazo group.


nitroarene

A nitrohydrocarbon that consists of an arene skeleton substituted by one or more nitro groups at unspecified positions.


N-nitro compound

A compound having the nitro group (-NO2) attached to a nitrogen atom.


Trp-Gly-Ile-His-His

A pentapeptide comprising L-tryptophan, glycine, L-isoleucine, and two L-histidine residues coupled in sequence by peptide linkages.


A glycotriaosylceramide having beta-D-galactosyl-(1->6)-beta-D-galactosyl-(1->4)-beta-D-glucose as the glycotriaosyl component.


GlyTouCan G02809YH

A composition-only glycan consisting of two hexosyl groups, three acetaminohexosyl groups and one 6-deoxyhexosyl groups  (identities and connectivity unknown). Composition: Hex2 HexNAc3 dHex1.


An amino trisaccharide that is 2-acetamido-2-deoxy-alpha-D-glucopyranose in which the hydroxy groups at positions 4 and 6 have been converted into the corresponding 2-acetamido-2-deoxy-beta-D-glucopyranosyl and alpha-L-fucopyranosyl derivatives, respectively.


An amino trisaccharide consisting of beta-D-galactopyranose, beta-D-glucopyranose and 2-acetamido-2-deoxy-D-galactopyranose residues joined in sequence by (1->4) and (1->3) glycosidic bonds.


A synthetic six-membered oligopeptide comprising Ac-Cha, Gpg, Tic, Met, betaPhPro and [S(oxaz)L]-NMe2 residues coupled in sequence.


A branched amino trisaccharide consisting of 2-acetamido-2-deoxy-D-glucopyranose in which the hydroxy groups at positions 3 and 6 have each been glycosylated by a alpha-L-fucopyranosyl group.


phosphonic acids

HP(=O)(OH)2  (phosphonic acid) and its P-substituted derivatives.


A diisocyanate consisting of dicyclohexylmethane with two isocyanate groups at the 4- and 4'-positions.


An amino tetrasaccharide that is beta-D-Manp-(1->4)-beta-D-GlcpNAc-(1->4)-D-GlcpNAc in which the hydroxy group at position 3 of the mannosyl group has been glycosylated by an alpha-D-mannopyranosyl residue.


2-tolyl isocyanate

An isocyanate comprising a benzene core with isocyanato- and methyl substituents ortho to each other.


A fifteen-membered glycopeptide comprising glycyl, isoleucyl, alanyl, glycyl, 3-(1,3-thiazol-4-yl)alanyl, (5R)-5-(beta-D-galactopyranosyloxy)lysyl, glycyl. alpha-glutamyl, glutaminyl, glycyl, prolyl, lysyl, glycyl, alpha-glutamyl and threonine residues coupled in sequence.


A member of the class of  hydrazines that is  hydrazine substituted by two methyl groups at position 1.


(S)-2-ureidoglycine zwitterion

The zwitterion resulting from the transfer of a proton from the carboxy group to the alpha-amino group of (S)-2-ureidoglycine.


An N-acyl-1-O-beta-D-glucosyl-15-methylhexadecasphing-4-enine in which the acyl group has 24 carbons and 0 double bonds and is 2-hydroxylated.


N-phosphotaurocyamine

The N-phospho derivative of taurocyamine.


An N-(2-hydroxyhexacosanoyl)phytosphingosine in which the 4-hydroxy group on the phytosphingosine portion has R-configuration.


trinitrophenol

A C-nitro compound comprising phenol having three nitro substtituents at the 2-, 4- and 6-positions.


organic amino compound

A compound formally derived from ammonia by replacing one, two or three hydrogen atoms by organyl groups.


A sialotetraosylceramide having beta-D-Gal-(1->3)-beta-D-GalNAc-(1->4)-[alpha-Neu5Gc-(2->3)]-beta-D-Gal-(1->4)-beta-D-Glc as the sialotetraosyl component.


Any member of the class of phytoceramides in which the sphingoid base is specified as Delta(8)-phytosphingenine.


N-hexanoyl-beta-D-galactosylsphinganine

A galactosylceramide that is beta-D-galactosylsphinganine in which the ceramide N-acyl group is specified as hexanoyl.


An amino trisaccharide consisting of 4,6-dideoxy-alpha-L-xylo-hexopyranose, beta-D-galactopyranose and 2-acetamido-2-deoxy-D-glucopyranose residues joined in sequence by (1->2) and (1->4) glycosidic bonds.


AcGly-Ser(O-D-alpha-D-Hep)-Gly-Leu

A derivatised tetrapeptide in which a parent tetrapeptide comprising glycine, L-serine, glycine and L-leucine residues coupled in sequence, has its terminal glycine residue acetylated on nitrogen and its serine residue D-glycero-alpha-D-heptosylated on oxygen.


GlyTouCan G03793VU

A composition-only glycan consisting of four hexosyl groups, two 2-acetaminohexosyl groups and three 6-deoxyhexosyl groups (identities and connectivity unknown). Composition: Hex4 HexNAc2 dHex3.


N-methylvaline

An N-methylamino acid that is the N-methyl derivative of valine.


An N-acyl-1-O-beta-D-glucosyl-15-methylhexadecasphing-4-enine in which the acyl group has 21 carbons and 0 double bonds.


Lys-Thr-Trp-Tyr

A tetrapeptide composed of L-lysine, L-threonine, L-tryptophan and L-tyrosine joined in sequence by peptide linkages.


D-cysteine derivative

A non-proteinogenic amino acid derivative resulting from the formal reaction of D-cysteine at the amino group, carboxy group, or thiol group, or from the replacement of any hydrogen of D-cysteine by a heteroatom.


N-octanoyldihydrosphingosine

A dihydroceramide in which the N-acyl group is specified as octanoyl.


A beta-D-glucoside that is the 2-azidoethyl glycoside of a tetrasaccharide (Streptococcus pneumoniae serotype 3 tetrasaccharide) consisting of two beta-D-glucuronosyl-(1->4)-beta-D-glucosyl disaccharide units linked (1->3).


ganglioside GA2 II3-sulfate

A ganglioside GA2 compound sulfated at the 3-position of the galactose ring


A phytoceramide in which the ceramide N-acyl group is specified as 2-hydroxyoctadecanoyl


histrelin

An oligopeptide comprising pyroglutamyl, histidyl, tryptophyl, seryl, tyrosyl, 1-benzyl-D-histidyl, leucyl, arginyl, and N-ethylprolinamide residues joined in sequence. It is a synthetic nonapeptide analogue of gonadotropin-releasing hormone, and is used as a subcutaneous hydrogel implant (particularly as the diacetate salt) for the treatment of prostate cancer and for the suppression of gonadal sex hormone production in children with central precocious puberty.


C20 dihydroceramide

A ceramide composed of C20 sphinganine having an unspecified fatty acyl group attached to the nitrogen.


neocasomorphin

A six amino acid oligopeptide fragment of the human milk protein, beta-casein.


A glycopeptide that consists of glycyl, phenylalanyl, (5R)-5-(beta-D-galactopyranosyloxy)lysyl, glycyl. alpha-glutamyl, glutaminyl, glycyl, prolyl, lysyl, glycyl, alpha-glutamyl and threonine residues coupled in sequence with an isostere-modified IlePsi(CH2CH2)Ala group attached to the amino terminus.


A L-ornithine derivative in which L-ornithine is acylated on both nitrogens.


name: N-[(2S)-3-(4-benzoylphenyl)-1-oxo-1-(prop-2-ynylamino)propan-2-yl]carbamic acid tert-butyl ester


Glu-Asp-Gln-Gln

A tetrapeptide composed of L-glutamic acid, L-aspartic acid and two L-glutamine units joined in sequence by peptide linkages.


A D-galactosyl-N-acylsphingosine where the ceramide N-acyl group is nonadecanoyl.


An amino trisaccharide consisting of alpha-L-fucopyranosyl, 2-O-methyl-beta-D-galactopyranosyl and 2-acetamidoD-glucopyranosyl residues linked in sequence by (1->3) and (1->4) glycosidic bonds.


A synthetic tetrapeptide comprising Ac-Cha, Arg, Tic and Met-NH2 residues coupled in sequence.


GlyTouCan G05127BN

A composition-only glycan consisting of one hexosyl group, three acetaminohexosyl groups, one 6-deoxyhexosyl group and one N-acetyl-neuraminic acid group (identities and connectivity unknown). Composition: Hex1 HexNAc3 dHex1 NeuAc1.


An amino disaccharide consisting of beta-D-galactofyanosyl and 2-acetamido-2-deoxy-D-glucopyranose residues joined in sequence by a (1->4) glycosidic bond.


A derivative of scyllo-inositol where the 1- and 3-hydroxy groups are replaced by guanidino and amino groups respectively.


A C-nitro compound in which the nitro compound is meta to the amino group and para to the methyl group of o-toluidine.


A member of the class of phenylureas that is urea in which one of the nitrogens is substituted by two methyl groups while the other is substituted by a phenyl group which carries two unspecified groups at positions 3 and 4 of the phenyl ring.


name: acetic acid [2-ethoxy-6-nitro-4-[[5-oxo-2-(prop-2-enylthio)-4-thiazolylidene]methyl]phenyl] ester


GlyTouCan G05049IC

A composition-only glycan consisting of six hexosyl groups, six acetaminohexosyl groups and two 6-deoxyhexosyl groups (identities and connectivity unknown). Composition: Hex6 HexNAc6 dHex2.


phenformin

A member of the class of biguanides that is  biguanide in which one of the terminal nitrogen atoms is substituted by a 2-phenylethyl group. It was used as an anti-diabetic drug but was later withdrawn from the market due to potential risk of  lactic acidosis.


alpha-galactosylphytosphingosine

A sphingoid derived from degradation of mammalian alpha-linked galactosylceramides by removal of the fatty acid by acid ceramidase.


FENURON

A member of the class of 3-(3,4-substituted-phenyl)-1,1-dimethylureas that is urea in which one of the nitrogens is substituted by a phenyl group while the other is substituted by two methyl groups. It is a herbicide used for the control of weeds in beetroot as well as various vegetable and ornamental crops.


A glycophytoceramide having a 4-O-[3-(4-methylphenyl)propyl]-alpha-D-galactosyl residue at the O-1 position and a hexacosanoyl group attached to the nitrogen. One of a series of an extensive set of 4"-O-alkylated alpha-GalCer analogues evaluated (PMID:30556652) as invariant natural killer T-cell (iNKT) antigens.


A sialotetraosylceramide having alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-[alpha-Neu5Ac-(2->6)]-beta-D-GalNAc-(1->4)-[alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)]-beta-D-Gal-(1->4)-beta-D-Glc as the sialotetraosyl component.


amidine

Derivatives of oxoacids RnE(=O)OH in which the hydroxy group is replaced by an amino group and the oxo group is replaced by =NR. In organic chemistry an unspecified amidine is commonly a carboxamidine.


An amino disaccharide consisting of 2-acetamido-2-deoxy-D-glucopyranose and 2-acetamido-2-deoxy-D-galactopyranose joined in sequence by a (1->3) glycosidic bond.


A sialotriaosylceramide consisting of beta-D-GalNAc-(1->4)-[alpha-Neu5Ac-(2->3)]-beta-D-Gal-(1->4)-beta-D-Glc attached to the primary hydroxy function of ceramide(d18:1/20:0).


CARBIMIDE

A carbodiimide in which both nitrogens are unsubstituted.


NITROSOBENZENE

A nitroso compound that is the nitroso derivative of benzene; a diamagnetic hybrid of singlet O2 and azobenzene.


A glycophytoceramide having an alpha-D-galactopyranosyl residue at the O-1 position and a 6-phenylhexanoyl group attached to the nitrogen.


sialopentaosylceramide

A ganglioside in which the oligosaccharide portion is composed of a pentasaccharide containing one or more sialic acid residues.


sialotetraosylceramide

A ganglioside in which the oligosaccharide portion is composed of an tetrasaccharide, to which one or more sialic acid residues are attached.


An organoammonium salt where dicyclohexylammonium is the cation and  alpha,N-(epsilon,N-DNP-aminocaproyl)-epsilon,N-DNP-L-lysinate is the counterion.


name: 2-[[cyclohexyl(oxo)methyl]amino]acetic acid [2-(4-cyanoanilino)-2-oxoethyl] ester


A sialotetraosylceramide consisting of a linear pentasaccharide made up from one sialyl residues, two galactose residues, one N-acetylglucosamine residue and a glucose residue at the reducing end attached to N-stearoylsphingosine via a beta-linkage.


A beta-D-glucosylceramide in which a beta-D-glucosyl residue is attached to the primary hydroxyl group of N-[omega-(9R)-hydroperoxy-(10E,12Z)-octadecadienoyloxy]acyl-sphing-4E-enine.


acylamide

A carboxamide of general formula RC(=O)NR2 where one or more of the R groups is an acyl group.


An N-acyl-D-galactosylsphingosine in which the ceramide N-acyl group is specified as 2-hydroxytricosanoyl.


A glycophytoceramide having an alpha-D-galactopyranosyl residue at the O-1 position and a 25-phenylpentacosanoyl group attached to the nitrogen.


pasireotide

A six-membered homodetic cyclic peptide composed from L-phenylglycyl, D-tryptophyl, L-lysyl, O-benzyl-L-tyrosyl, L-phenylalanyl and modified L-hydroxyproline residues joined in sequence. A somatostatin analogue with pharmacologic properties mimicking those of the natural hormone somatostatin; used (as its diaspartate salt) for treatment of Cushing's disease.


name: phosphatidylethanolamine amidated glycyl residue(1-)


valine derivative

An amino acid derivative resulting from reaction of valine at the amino group or the carboxy group, or from the replacement of any hydrogen of valine  by a heteroatom. The definition normally excludes peptides containing valine  residues.


A glycophytoceramide having an alpha-D-glucosyl residue at the O-1 position and a hexacosanoyl group attached to the nitrogen.


A glycotriaosylceramide having alpha-N-acetylneuraminyl-(2->6)-beta-D-galactosyl-(1->4)-beta-D-glucose as the trisaccharide component.


name: Imidazolidine-1-carboxylic acid, 2-t-butyl-5-isobutyl-3-methyl-4-oxo-, t-butyl ester


artificial glycosphingolipid

Any glycosphingolipid designed and synthesized for the purposes of research.


An amino disaccharide consisting of 2-acetamido-2-deoxy-beta-D-glucopyranose residue and a 2-acetamido-2-deoxy-alpha-D-glucopyranose residue joined in sequence by a (1->3) glycosidic bond.


A beta-D-glucosyl-(1<->1')-N-acylsphinganine in which the acyl group specified is hexadecanoyl.


D-glucosyl-N-tetracosanoylsphinganine

A glycodihydroceramide that is a sphinganine derivative having a D-glucosyl group at the 1-position and a tetracosanoyl group attached to the nitrogen.


A glycophytoceramide having an alpha-D-galactopyranosyl residue at the O-1 position and an 8-([1,1'-biphenyl]-4-yl)octanoyl group attached to the nitrogen.


A glucosylceramide consisting of a beta-D-glucosyl residue attached to the primary hydroxyl group of N-acylated C20 sphingosine.


An N-(3-aminopropyl)but-2-ene-1,4-diamine having a cis-double bond.


An amino trisaccharide consisting of 2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-glucopyranose and D-glucopyranose residues joined in sequence by (1->6) and (1->2) glycosidic bonds.


A glycotetraosylceramide having beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl component attached to the primary hydroxy function of a ceramide with d18:0 sphingoid base and undefined fatty acyl chain.


nitroglycerol

A nitrate ester that is glycerol in which nitro group(s) replace the hydrogen(s) attached to one or more of the hydroxy groups.


An amino disaccharide consisting of and alpha-L-fucose residue and a 2-acetamido-2-deoxy-D-glucopyranose residue joined in sequence by a (1->4) glycosidic bond.


An N-sulfonylcarboxamide that is (Z)-11-methyldodec-2-enamide in which one of the hydrogens attached to the nitrogen is replaced by a methanesulfonyl (mesyl) group.


An amino trisaccharide consisting of alpha-D-mannopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose and 2-acetamido-2-deoxy-D-glucopyranose residues joined in sequence by (1->4) glycosidic bonds.


An amino disaccharide consisting of beta-D-galacopyranose and 2-acetamido-2-deoxy-beta-D-galactopyranose residues joined in sequence by a (1->4) glycosidic linkage.


An amino disaccharide consisting of two 2-acetamido-2-deoxy-beta-D-glucopyranose residues joined by a (1->6) glycosidic bond.


nitroguanidine derivative

Any N-nitro compound obtained by formal replacement of one or more of the hydrogens of a nitroguanidine by an organyl group.