poly(phenylene) macromolecule

A homopolymer macromolecule composed of sigma-bonded benzene or substituted benzene rings.


rhamnogalacturonan I

A family of polysaccharides that all contain a linear backbone composed of repeating units of the disaccharide alpha-D-GalpA-(l->2)-alpha-L-Rhap joined by alpha-(1->4) linkages.


locked nucleic acid

Nucleic acid polymers where the residues contain 'locked' deoxyribose units and are linked by phosphodiester bonds. The deoxyribose unit conformation is 'locked' by a 2'-C,4'-C-oxymethylene link.


ionomer macromolecule

A macromolecule that contain both neutral and charged repeating units.


Polypropylene glycol (m w 1,200-3,000)

A macromolecule composed of repeating propyleneoxy units.


A polysaccharide derivative made up of repeating units of alpha-D-Galp-(1->4)-alpha-D-NeupAc, joined together by glycosidic linkages between position 2 of the N-acetylneuraminyl residues and position 6 of the galactosyl residues.


GlyTouCan G93860XO

A polysaccharide that is alpha-D-Manp-(1->3)-[beta-D-Manp-(1->6)]-beta-D-Manp-(1->4)-beta-D-GlcpNAc-(1->4)-beta-D-GlcpNAc in which a hydroxy group in one of the terminal mannose moieties has been converted into the corresponding Neu5Ac-(1->?)-?-D-Gal-(1->?)-?-D-GlcNAc-(1->?)- glycoside, while two of the hydroxy groups on the other terminal mannose moiety have each been converted into the corresponding Neu5Ac-(1->?)-?-D-Gal-(1->?)-?-D-GlcNAc-(1->?)- glycoside.    For the structure shown, either one of the R1 atoms and two of the R2 atoms represent Neu5Ac-(1->?)-?-D-Gal-(1->?)-?-D-GlcNAc-(1->?)- groups or vice versa; the remaining R1 and R2 atoms are hydrogens.


WHWLQLKPGQPMY

A thirteen-membered polypeptide comprising the sequence Trp-His-Trp-Leu-Gln-Leu-Lys-Pro-Gly-Gln-Pro-Met-Tyr. Corresponds to the P01149[90-102] fragment of mating factor alpha-1 from Saccharomyces cerevisiae (strain ATCC 204508/S288c).


MELITTIN

A 26-membered polypeptide consisting of Gly, Ile, Gly, Ala, Val, Leu, Lys, Val, Leu, Thr, Thr, Gly, Leu, Pro, Ala, Leu, Ile, Ser, Trp, Ile, Lys, Arg, Lys, Arg, Gln and Gln-NH2 residues joined in sequence. It is the principal active component of bee venom.


A copolymer composed of repeating N-(propanamidomethyl)propanamide and 2-methylpropanoic acid units.


poly(thiophene-2,5-diyl) macromolecule

A macromolecule composed of repeating thiophenyl units connected at the 2- and 5-positions.


A copolymer of beta-D-mannopyranosyl-(1->2)-beta-D-mannopyranosyl-(1->2)-alpha-D-mannopyranoside and copovidone and comprised of N-(2-{[beta-D-mannopyranosyl-(1->2)-beta-D-mannopyranosyl-(1->2)-alpha-D-mannopyranosyl]oxy}ethyl)-N'-[(1-vinyl-1H-1,2,3-triazol-4-yl)methyl]pentanediamide, vinyl alcohol and N-vinyl-2-pyrrolidone units.


poly(N-acetyllactosamine)

An aminoglycan composed of a backbone of N-acetyllactosamine repeating units that are joined to each other via beta-(1->3)-linkages.


A biomacromolecule comprised of repeating D-glutamic acid residues linked by peptidic bonds between the amino and gamma-carboxy groups.


A polysaccharide composed of a backbone of repeating alpha-D-rhamnosyl-(1->3)-alpha-D-rhamnosyl-(1->2)-alpha-D-rhamnosyl units, joined by (1->3)-linkages.


A polysaccharide derivative composed of a backbone of alpha-D-Gal-(1->3)-[alpha-L-Fuc-(1->2)]-beta-D-Gal-(1->3)-alpha-D-GalNAc-(1->3)-D-GalNAc branched pentasaccharide repeating units that are joined to each other via alpha(1->2)-linkages; corresponds to the O-antigen repeat unit structure of E. coli O86:B7.


A mimotope of the pyruvate dehydrogenase E2 component (PDC-E2) comprising a (2E)-3-[2-(trifluoromethyl)phenyl]prop-2-enoyl- group linked to the lipoated PDC-E2 core dodecapeptide (DKATIGFEVQEE) at N-6 of lysine.


DASKALRSSGMP

A twelve-membered polypeptide comprising the sequence Asp-Ala-Ser-Lys-Ala-Lys-Arg-Ser-Ser-Gly-Met-Pro.


GAMMA-CYCLODEXTRIN

A cycloamylose composed of eight alpha-(1->4) linked D-glucopyranose units.


poly(hydroxybutyrate)

A polymer composed of repeating hydroxybutyryl units.


poly(beta-methylstyrene)

A polymer composed of repeating propylbenzene units.


poly(divinylbenzene) macromolecule

A macromolecule composed of repeating phenylenediethylene units.


poly(3-alkoxythiophene) macromolecule

A macromolecule composed of repeating 3-alkoxythiophene units.


polysiloxane macromolecule

A macromolecule with a [-Si(R2)-O-] repeating unit.


A macromolecule composed of repeating 1,2-dihydroxyethyl 2-methylpropanoate units.


poly(9,9'-fluorene) macromolecule

A macromolecule composed of repeating substituted or unsubstituted fluorene units linked at the 9- and 9'-positions.


name: S. flexneri serotype X O-specific polysaccharide

description: A polysaccharide derivative antigen composed of a backbone of repeating alpha-D-Glc-(1->3)-alpha-L-Rha-(1->2)-alpha-L-Rha-(1->3)-alpha-L-Rha-(1->3)-beta-D-GlcNAc units that are connected via beta-(1->2)-linkages between the GlcNAc and the Rha residue adjacent to Glc.


conjugated macromolecule

A macromolecule composed of a main chain containing a sequence of conjugated multiple bonds.


paraformaldehyde macromolecule

A macromolecule composed of repeating methyleneoxy units arising from polymerisation of formaldehyde.


poly(arginine) macromolecule

A macromolecule composed of repeating arginyl units joined via peptide linkages.


mannogen

A mannose-containing polysaccharide that is a major energy reserve in Leishmania. It is comprised of linear chains of beta-1,2-linked mannose residues (2-60 residues in length depending on development stage).


A dendrimer macromolecule consisting of a malonamide core, each N of which carries a 2-(bis{2-[(2-aminoethyl)amino]-2-oxoethyl}amino)ethyl branch and with a 2-(2-{2-[(prop-2-yn-1-yl)oxy]ethoxy}ethoxy)ethyl substituent at C-2.


laminarin

A polysaccharide composed of beta-(1->3)-linked glucose residues containing sporadic beta-(1->6)-linkages as branch points or inter-residue linkages and 2-3% D-mannitol at some reducing termini.


A heparin dodecasaccharide consisting of 4-deoxy-2-O-sulfo-alpha-L-threo-hex-4-enopyranuronosyl, 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranosyl, 2-O-sulfo-alpha-L-idopyranuronosyl, 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranosyl, 2-O-sulfo-alpha-L-idopyranuronosyl, 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranosyl, 2-O-sulfo-alpha-L-idopyranuronosyl, 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranosyl, 2-O-sulfo-alpha-L-idopyranuronosyl, 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranosyl, 2-O-sulfo-alpha-L-idopyranuronosyl, and 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose units joined in sequence by (1->4) linkages. Sequence: DUAp2S-(1-4)-a-D-GlcNpS6S-(1-4)-a-L-IdoAp2S-(1-4)-a-D-GlcNpS6S-(1-4)-a-L-IdoAp2S-(1-4)-a-D-GlcNpS6S-(1-4)-a-L-IdoAp2S-(1-4)-a-D-GlcNpS6S-(1-4)-a-L-IdoAp2S-(1-4)-a-D-GlcNpS6S-(1-4)-a-L-IdoAp2S-(1-4)-a-D-GlcNpS6S.


name: type Ib group B Streptococcus capsular polysaccharide

description: A polysaccharide derivative that is the capsular polysaccharide of type Ib group B Streptococcus, consisting of saccharide chains involving alpha-D-NeuNAc-(2->3)-beta-D-Galp, beta-D-Galp-(1->3)-beta-D-GlcpNAc, beta-D-GlcpNAc-(1->3)-beta-D-Galp, beta-D-Galp-(1->4)-beta-D-Glcp and beta-D-Glcp-(1->4)-beta-D-Galp linkages. The whole can be conjugated to a carrier protein (e.g. CRM197 and tetanus toxoid) randomly along the polysaccharide chain (cross-linked). An example structure is shown in the diagram.


glucan derivative

A homopolysaccharide derivative which is formally derived from a glucan.


A macromolecule composed of repeating 2-(acetoacetoxy)ethyl methacrylate units.


precursor messenger RNA

An immature or incompletely processed mRNA molecule that needs to be processed before it becomes a fully functional mature mRNA. Pre-mRNA is synthesized from a DNA template in the cell nucleus by transcription and lacks structures that the mRNA requires. First all introns have to be removed from the transcribed RNA through a process known as splicing. Before the RNA is ready for export, a Poly(A)tail is added to the 3' end of the RNA and a 5' cap is added to the 5' end.


homogalacturonan

A pectidic polymer, characterized by a backbone of 1,4-linked alpha-D-GalpA residues that can be methyl-esterified at C-6 and carry acetyl groups on O-2 and O-3.


fructan

Polysaccharides composed of fructose residues.


name: glycogen (amylose chain)n-[(1->6)-amylose chain]4


ionic macromolecule

A macromolecule containing ionic groups.


polihexanide

A homopolymer macromolecule composed of repeating N-hexyltriimidodicarbonic diamide units. It is used as a disinfectant, antiseptic, and antifungal agent. Also commonly used as a swimming pool and spa water sanitizer.


A mimotope of the pyruvate dehydrogenase E2 component (PDC-E2) comprising a [(2E)-3-(m-tolyl)prop-2-enoyl]- group linked to the lipoated PDC-E2 core dodecapeptide (DKATIGFEVQEE) at N-6 of lysine.


nucleic acid

A macromolecule made up of nucleotide units and hydrolysable into certain pyrimidine or purine bases (usually adenine, cytosine, guanine, thymine, uracil), D-ribose or 2-deoxy-D-ribose and phosphoric acid.


afamelanotide

A polypeptide comprising of 13 amino acids which is an analogue of alpha-melanocyte stimulating hormone. It is approved as a dermatologic drug for the prevention of phototoxicity in adult patients with erythropoietic protoporphyria.


ACTH

A polypeptide hormone produced and secreted by the pituitary gland comprising 39 amino acid residues coupled in a linear sequence. The N-terminal 24-amino acid segment is identical in all species and contains the adrenocorticotrophic activity. Corticotropin stimulates the cortex of the adrenal gland and boosts the synthesis of corticosteroids, mainly glucocorticoids but also sex steroids (androgens). It is used in the treatment of certain neurological disorders such as infantile spasms and multiple sclerosis, and diagnostically to investigate adrenocortical insufficiency.


block copolymer

A polymer which is composed of two or more blocks of homopolymers in a linear sequence.


polycationic macromolecule

A macromolecule carrying multiple positive charges.


graft copolymer

A copolymer comprising molecules with one or more species of block connected to the main chain as side chains. The side chains contain at least one different species of monomer to the main chain.


A diblock copolymer composed of adjacent blocks of poly(methyl acrylate) and deuterated polystyrene.


A beta-D-glucan of more than 20 D-glucose residues joined by beta-(1->3) and beta-(1->4) glycosidic linkages.


cellodextrin

A dextrin of varying length (two or more glucose monomers) resulting from cellulolysis, the breakdown of cellulose.


KGKGKGKGKGENPVVAFFKNIVTPRTP

A linear 27-membered polypeptide comprising the sequence Lys-Gly-Lys-Gly-Lys-Gly-Lys-Gly-Lys-Gly-Glu-Asn-Pro-Val-Val-Ala-Phe-Phe-Lys-Asn-Ile-Val-Thr-Pro-Arg-Thr-Pro. Corresponds to the sequence of the myelin basic protein 83-99 (MBP83-99) immunodominant epitope with the histidyl residue at position 88 replaced by alanyl [MBP83-99(A(88))] and with an (L-lysylglycyl)5 [(KG5)] linker attached to the glutamine(83) (E(83)) residue.


A glycosylglycerol derivative in which the glycosyl moiety of glycosyl-sn-glycerol is N-acetyl-beta-D-glucosaminyl-(1->3)-[(D-glyceric acid)-(2->1)]-beta-D-glucosaminyl-(6-phospho-6)-N-acetyl-beta-D-glucosaminyl-(1->3)-[(D-glyceric acid)-(2->1)]-beta-D-glucosaminyl-(6-phospho-6)-N-acetyl-beta-D-glucosaminyl-(1->3)-[(D-glyceric acid)-(2->1)]-beta-D-glucosaminyl-(6-phospho-6)-beta-D-glucosyl-(1->6)-beta-D-glucosyl-(1->6)-beta-D-glucosyl attached at O-3, with O-1 and O-2 both carrying myristoyl substituents. Synthetic C. difficile lipoteichoic acid (LTA) molecule consisting of lipid + core region and three [(->6)-alpha-D-GlcpNAc-(1->3)-[P-6]-alpha-D-GlcpNAc-(1->2)-D-GroA polymeric repeats (where P-6 is a phosphodiester bridge and GroA is glyceric acid).


A macromolecule composed of repeating 2-ethenylfuran units.


mastoparan-A

A member of the class of mastopyrans that is a 14-amino acid polypeptide comprising isoleucyl, lysyl, tryptophyl, lysyl, alanyl, isoleucyl, leucyl, aspartyl, alanyl, valyl, lysyl, lysyl, valyl, and isoleucinamide residues coupled in sequence. It is the major active component of the venom of the hornet Vespa analis and causes degranulation of mast cells. It exhibits antimicrobial activity against both Gram-positive and -negative bacteria as well as haemolytic activity on chicken, human and sheep erythrocytes.


YSPFHKWFPSMH

A twelve-membered polypeptide comprising the sequence Tyr-Ser-Pro-Phe-His-Lys-Trp-Phe-Pro-Ser-Met-His.


poly(styrene-4-sulfonic acid)

A polymer composed of repeating 4-ethylbenzenesulfonic acid units.


poly(acrylonitrile) macromolecule

A macromolecule composed of repeating cyanoethylene units.


A xylan compound with beta-(1->4)-linkages between each xylose.


tesamorelin

A polypeptide that is a synthetic analogue of human GRF (Growth Releasing Factor) comprised of the 44 amino-acid sequence of human GRF with a hex-3-enoyl moiety attached to the tyrosine residue at the N-terminal part of the molecule. It is used to stimulate human GRF receptors.


heteropolyacid macromolecule

A macromolecule composed of hydrogen and oxygen with certain metals (W, Mo, V) and non-metals (Si, P, As).


poly(N-dodecylacrylamide) macromolecule

A macromolecule composed of repeating 1-(dodecylcarbamoyl)ethylene units.


A mimotope of the pyruvate dehydrogenase E2 component (PDC-E2) comprising a 6-bromohexanoyl group linked to the lipoated PDC-E2 core dodecapeptide (DKATIGFEVQEE) at N-6 of lysine.


galactoglucomannan

A heteroglycan that consists of a backbone of randomly distributed (1->4)-linked mannose and glucose units with (1->6)-linked galactose units attached to mannose units.


chondroitin 6'-sulfate

A chondroitin sulfate in which the site of sulfation is carbon 6 of the N-acetylgalactosamine (GalNAc) sugar.


poly(ribitol phosphate) teichoic acid

One of the teichoic acids found in the cell walls of Gram-positive bacteria.


poly(hydroxyalkanoate)

A polymer composed of repeating hydroxyalkanoyl units.


name: P. aeruginosa serotype O11 O-specific polysaccharide

description: A polysaccharide composed of a backbone of linear trisaccharide repeating units that are joined to each other via beta-(1->4)-linkages. An epitope, it is the O-polysaccharide portion of the lipopolysaccharide from Pseudomonas aeruginosa serotype O11.


galactoxylomannan

An exopolysaccharide composed of an alpha-(1->6)-galactan backbone containing four potential short oligosaccharide branch structures, produced by the human pathogenic fungus Cryptococcus neoformans, that produces immune paralysis in some animals, including humans.


A branched polysaccharide derivative composed of a backbone of repeating beta-D-Gal-(1->4)-beta-D-Glc-(1->6)-[alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->4)]-beta-D-GlcNAc units, joined by (1->3)-linkages as shown. Group B Streptococcus (GBS) type III capsular polysaccharide.


A (1->3)-beta-D-glucan consisting of 12 glucosyl residues linked in a linear sequence.


A polysaccharide derivative composed of repeating disaccharide units, consisting of (1->3)-linked residues of 2,4-diacetamido-2,4-dideoxy-beta-D-quinovose (2,4-diacetamido-2,4,6-trideoxy-beta-D-glucose, bacillosamine) and 2-acetimidoylamino-2-deoxy-beta-D-glucuronic acid.


(S)-glycol nucleic acid

Glycol nucleic acids with an (S) chiral centre in the glycol backbone. They can be synthetically derived from (S)-(+)-glycidol.


galacturonan derivative

Any polysaccharide derivative obtained from a galacturonan.


A diblock copolymer composed of adjacent blocks of polystyrene and poly(2-vinylpyridine).


bivalirudin

A synthetic peptide of 20 amino acids, comprising D-Phe, Pro, Arg, Pro, Gly, Gly, Gly, Gly, Asn, Gly, Asp, Phe, Glu, Glu, Ile, Pro, Glu, Glu, Tyr, and Leu in sequence. A congener of hirudin (a naturally occurring drug found in the saliva of the medicinal leech), it a specific and reversible inhibitor of thrombin, and is used as an anticoagulant.


name: A. haemolyticus strain 61 O-specific polysaccharide

description: A polysaccharide derivative composed of a backbone of linear trisaccharide-derivative repeating units that are joined to each other via beta-(1->3)-linkages. An antigen, it is the O-polysaccharide of the lipopolysaccharide from Acinetobacter haemolyticus strain 61.


A polymer composed of repeating 1-(azidomethyl)-4-ethylbenzene units.


poly[d(TC)]

A single-stranded DNA polynucleotide consisting of a repeating unit of thymidine and deoxycytidine residues, with all residues connected by 3'->5' phosphodiester linkages.


poly(glycolic acid)

A polymer composed of repeating hydroxyacetic acid units.


A branched beta-D-glucan that consists of a beta-1,3-linked nonaglucan backbone with a beta-1,3-glucodiaose branch at the 6-O-position of the nonaglucan central sugar unit.


A polysaccharide derivative composed of repeating sialyl residues connected by alternating (2->8) and (2->9) linkages.


A mannan consisting of repeating mannosyl units joined via beta-(1->2)-linkages.


A macromolecule composed of repeating 2-ethylhexyl 2-methylpropanoate units.


A polysaccharide consisting of alpha-D-Manp-(1->2)-alpha-D-Manp-(1->2)-alpha-D-Manp-(1->3)-beta-D-Manp-(1->4)-beta-D-GlcpNAc-(1->4)-alpha-D-GlcpNAc in which the hydroxy group at position 6 of the beta-D-Manp group is substituted by an alpha-D-Manp-(1->2)-alpha-D-Manp-(1->3)-[alpha-D-Manp-(1->2)-alpha-D-Manp-(1->6)-]-alpha-D-Manp group.


name: P. stuartii O4 O-specific polysaccharide

description: A polysaccharide-derived antigen from Providencia stuartii composed of a backbone of branched tetrasaccharide repeating units comprised of alternating beta-D-galactose and N-acetylglucosamine residues joined to each other via beta-(1->3)- or -(1->6)-linkages, with an N-acetyl-L-asparaginyl-alpha-D-quinovosyl side-chain attached by a (1->6)-linkage to one of the galactosyl residues.


bisphenol A polycarbonate macromolecule

A macromolecule composed of bisphenol A units connected by carbonate (-O-(C=O)-O-)  groups.


polythiourethane macromolecule

A macromolecule composed of units connected by thiourethane (-NH-C(=S)-O-) linkages.


N-glycan derivative

The term used to refer to the 'carbohydrate' portion of N-glycoproteins when attached to a nitrogen from asparagine or arginine side-chains, when this portion is a carbohydrate derivative.


hyperbranched macromolecule

A macromolecule having many branched main chains attached to the backbone.


A biomacromolecule consisting of a backbone of beta-D-ribosyl-(1->1)-D-ribitol-5-phosphate repeating units that are joined to each other by phosphodiester linkages.


poly[d(GAA)]

A single-stranded DNA polynucleotide consisting of a repeating sequence of one deoxyguanosine residue and two deoxycytosine residues, with all residues connected by 3'->5' phosphodiester linkages.


A branched pentasaccharide consisting of a D-GlcNAc residue at the reducing end with an alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc moiety attached via a beta-(1->4) linkage.


A macromolecule composed of repeating 6-(1,3-benzoxazol-6-yl)-2-phenyl-1,3-benzoxazole units.


Major species at pH 7.3.


A polysaccharide derivative comprising a trisaccharide repeating unit consisting of N-acetyl-beta-D-mannosaminouronic acid, N-acetyl-alpha-L-fucosamine and N-acetyl-beta-D-fucosamine residues linked sequentially (1->3), with the trisaccharide repeats themselves also being linked (1->3); corresponds to the de-O-acetylated serotype 8 (CP8) capsular polysaccharide of Staphylococcus aureus.


polyurethane macromolecule

A homopolymer macromolecule composed of units connected by carbamate (-O-CO-NH-) linkages.


polystyrene-block-poly(acrylic acid)

A diblock copolymer composed of adjacent blocks of polystyrene and poly(acrylic acid).


A polysaccharide composed of a backbone of alpha-L-arabinofuranosyl-(1->3)-6-deoxy-alpha-L-gulo-heptopyranosyl repeating units that are joined to each other via (1->3)-linkages.


poly(sulfone) macromolecule

A homopolymer macromolecule composed of repeating units connected by sulfonyl (-SO2-) linkages.


An ionic macromolecule obtained by deprotonation of the terminal carboxy group of poly(6-aminohexanoic acid).


d8-PMMA macromolecule

A macromolecule composed of repeating fully deuterated methyl methacrylate units.


pseudopeptidoglycan

A peptidoglycosaminoglycan formed by alternating residues of beta-(1->3)-linked N-acetylglucosamine and N-acetyltalosaminuronic acid residues. Attached to the carboxy group of the talosaminuronic acid is a peptide chain of three to five amino acids.


A mimotope of the pyruvate dehydrogenase E2 component (PDC-E2) comprising a 5-chloropentanoyl group linked to the lipoated PDC-E2 core dodecapeptide (DKATIGFEVQEE) at N-6 of lysine.


small nuclear RNA

A class of small RNA molecules which are comprised of approximately 150 nucleotides and which are found within the nucleus of eukaryotic cells.


A branched polysaccharide derivative composed of a backbone of repeating [alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->6)]-beta-D-Glc-(1->4)-beta-D-Gal-(1->4)-beta-D-Glc units, joined by (1->4)-linkages as shown.


name: D-glucose- and/or D-galactose-substituted mannan

description: A heteroglycan in which a backbone composed of D-mannose units is substituted with D-glucose and/or D-galactose units.


poly(ethylene)

A polymer composed of ethane units.


periodic copolymer

A copolymer consisting of macromolecules comprising more than two species of monomeric units in regular sequence.


A mimotope of the pyruvate dehydrogenase E2 component (PDC-E2) comprising a {(2E)-3-[4-(trifluoromethyl)phenyl]prop-2-enoyl}-group linked to the lipoated PDC-E2 core dodecapeptide (DKATIGFEVQEE) at N-6 of lysine.


name: A. haemolyticus strain 57 O-specific polysaccharide

description: A polysaccharide derivative composed of a backbone of linear trisaccharide-derivative repeating units that are joined to each other via alpha-(1->3)-linkages. An antigen, it is the O-polysaccharide of the lipopolysaccharide from Acinetobacter haemolyticus strain 57.


K antigen

Any capsular polysaccharide derivative which is carried on the surface of a bacterial capsule or formed on the outer portion of a cell wall and masks somatic O antigens.


poly(vinylene fluoride)

A polymer composed of repeating 1,1-difluoroethyl units.


name: P. mirabilis O29 O-specific polysaccharide

description: A polysaccharide-derived antigen composed of a backbone of branched tetrasaccharide-derivative repeating units that are joined to each other via beta-(1->3)-linkages.


name: P. stuartii O33 O-specific polysaccharide

description: A polysaccharide derivative composed of a backbone of linear derivatised-tetrasaccharide repeating units that are joined to each other via beta-(1->6)-linkages.


P-factor

A polypeptide of 23 residues, with the sequence Thr-Tyr-Ala-Asp-Phe-Leu-Arg-Ala-Tyr-Gln-Ser-Trp-Asn-Thr-Phe-Val-Asn-Pro-Asp-Arg-Pro-Asn-Leu. A peptide pheromone released by Schizosaccharomyces pombe cells of the cellular mating type Plus.


A beta-D-glucan consisting of (1->4)-beta-D-glucan in which the residue at the non-reducing end has undergone formal dehyderogenation resulting on conversion of the hydroxy group at position 4 to the corresponding ketone.


poly(isobornyl acrylate) macromolecule

An acrylic macromolecule composed of repeating 1,7,7-trimethylbicyclo[2.2.1]heptan-2-yl (isobornyl) propanoate units.


A heparin dodecasaccharide consisting of 4-deoxy-2-O-sulfo-alpha-L-threo-hex-4-enopyranuronosyl, 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranosyl, 2-O-sulfo-alpha-L-idopyranuronosyl, 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranosyl, 2-O-sulfo-alpha-L-idopyranuronosyl, 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranosyl, 2-O-sulfo-alpha-L-idopyranuronosyl, 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranosyl, alpha-L-idopyranuronosyl, 2-acetamido-2-deoxy-6-O-sulfo-alpha-D-glucopyranosyl, beta-D-glucopyranuronosyl, and 2-deoxy-3,6-di-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose units joined in sequence by (1->4) linkages. Sequence: DUA2S-GlcNS6S-IdoA2S-GlcNS6S-IdoA2S-GlcNS6S-IdoA2S-GlcNS6S-IdoA-GlcNAc6S-GlcA-GlcNS3S6S.


PCM 2477 oligosaccharide

The eleven-membered core polysaccharide derivative from Yokenella regensburgei strain PCM 2477.


poly(ether) macromolecule

A macromolecule composed of units connected by ether (-O-) linkages.


glucomannan

A heteroglycan consisting of beta-(1->4)-linked D-glucose (G) and D-mannose (M) in a proportion of 5:8. The basic polymeric repeating unit has the pattern: GGMMGMMMMMGGM, with branching through beta-(1->3)- and beta-(1->6)-glucosyl linkages. Acetate groups are present on C-6 every 9-19 units of the main chain.


Burkholderia spp. O-polysaccharide

Any of the O-polysaccharides present as part of the lipopolysaccharides of Burkholderia species.


isotactic macromolecule

A polymer in which all the substituents are located on the same side of the backbone.


name: poly(perylene bisimide acrylate) macromolecule

description: A macromolecule composed of repeating perylene bismide acrylate units.


homopolymer macromolecule

A macromolecule derived from one species of (real, implicit or hypothetical) monomer.


peptidoglycan

A peptidoglycosaminoglycan formed by alternating residues of beta-(1->4)-linked N-acetylglucosamine and N-acetylmuramic acid {2-amino-3-O-[(S)-1-carboxyethyl]-2-deoxy-D-glucose} residues. Attached to the carboxy group of the muramic acid is a peptide chain of three to five amino acids.


agarose

A linear polysaccharide made up from alternating D-galactose and 3,6-anhydro-alpha-L-galactopyranose residues joined by alpha-(1->3)- and beta-(1->4)-linkages.


poly(menthide) macromolecule

A macromolecule composed of repeating (3R,6S)-6-hydroxy-3,7-dimethyloctanoyl units.


A polysaccharide derivative composed of a backbone of beta-D-GlcNAc-(1->4)-L-Rha repeating units that are joined to each other via alpha-(1->3)-linkages; corresponds to the repeating unit of the O-polysaccharide from Pasteurella haemolytica serotypes 3 and 15.


A polysaccharide derivative consisting of a chain of 2-acetamido-2-deoxy-beta-D-galactopyranose units joined  together by (1->6)-glycosidic linkages, with each unit substituted by a beta-D-glucopyranuronic acid, attached by a (1->3) linkage.


poly(vinyl methyl ether) macromolecule

A macromolecule composed of repeating methoxyethyl groups.


penicilloyl polylysine

A polypeptide in which the epsilon-amino group of each L-lysine residue in poly-L-lysine is substituted with a benzylpenicilloyl group.


A polysaccharide derivative with a repeating unit consisting of beta-D-galactosyl, beta-D-galactosyl and beta-D-glucosyl residues linked sequentially (1->3) and (1->4), to the galactosyl residue at the non-reducing end of which is attached an N-acetyl-beta-D-galactosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl disaccharide unit via a (1->3) linkage, with all repeating units being linked (1->6). Desialylated capsular polysaccharide of Streptococcus suis serotype 1.


A polysaccharide derivative composed of a backbone of linear tetrasaccharide derivative repeating units that are joined to each other via beta-(1->6)-linkages.


name: E. coli O65:K-:H- O-specific polysaccharide

description: A polysaccharide-derived antigen composed of a backbone of linear pentasaccharide-derivative repeating units that are joined to each other via alpha-(1->2)-linkages.


A branched polysaccharide composed of a backbone of repeating alpha-D-Rhap-(1->3)-[alpha-D-Fucp-(1->4)]-alpha-D-Rhap-(1->2)-alpha-D-Rhap-(1->2)-alpha-D-Rhap units, joined by (1->3)-linkages as shown.


DSGEGDFLAEGGGVR

A fifteen-membered polypeptide consisting of Asp, Ser, Gly, Glu, Gly, Asp, Phe, Leu, Ala, Glu, Gly, Gly, Gly, Val and Arg residues joined in sequence.


polybutylene adipate terephthalate

A random copolymer of adipic acid, 1,4-butanediol and terephthalic acid.


insulin

An insulin that is produced in the pancreas and involved in regulating the metabolism of carbohydrates (particularly glucose) and fats. Commonly thought of as a protein, it consists of two peptide chains, one containing 21 amino acid residues and the other containing 30; the chains are joined together by 2 disulfide bonds. Recombinant insulin is identical to human insulin, but is synthesised by inserting the human insulin gene into E. coli, which then produces insulin for human use. It is used in the treatment of type I and type II diabetes.


poly(cytidylic acid)

A polynucleotide comprised of cytidine units connected via 3'->5' phosphodiester linkages.


laminarihexaose

A beta-D-glucan in which six D-glucose residues are connected by beta(1->3) linkages.


arabinan

A polysaccharide composed of arabinose residues.


poly(phenylene oxide) macromolecule

A macromolecule composed of repeating substituted or un-substituted phenyleneoxy units.


polyacetylene macromolecule

A macromolecule prepared from substituted or unsubstituted acetylene (ethyne) units.


cyclodextrin

A macrocycle composed of five or more D-glucopyranose units bonded via (1->4)-linkages.


A macromolecule composed of repeating trimethyl({2-[({2-[(2-methylpropanoyl)oxy]ethyl} phosphonato)oxy]ethyl})azanium units.


sodium polystyrene sulfonate

A polymer composed of repeating sodium ethylbenzenesulfonate units (position of substitution not specified).


poly(glycyl-L-arginine)

A polypeptide composed of dipeptide Gly-Arg units joined via peptide linkages.


A macromolecule composed of repeating 2,7-diethenyl-9H-carbazole units.


polybenzoxazole macromolecule

A macromolecule composed of units connected by benzoxazole linkages.


poly[d(TCC)]

A single-stranded DNA polynucleotide consisting of a repeating sequence of one thymidine residue and two deoxycytidine residues, with all residues connected by 3'->5' phosphodiester linkages.


name: Proteus genomospecies 3J-r O-specific polysaccharide

description: A polysaccharide derivative consisting of a repeating unit of beta-D-glucuronosyl, beta-D-galacturonosyl and N-acetyl-beta-D-glucosaminyl residues linked sequentially (1->3) and (1->3), to the glucuronosyl and N-acetylglucosaminyl residues of which are linked respectively (1->2) and (1->6) an N-acetyl-beta-D-glucosaminyl residue and an alpha-D-glucosyl residue, while the galacturonosyl residue forms an amide with 3-O-acetyl-L-threonine, the complete pentasaccharide repeating units all being linked (1->4). The O-polysaccharide of Proteus  genomospecies 3J-r.


poly(2,5-furan) macromolecule

A polyfuran macromolecule composed of unsubstituted furan rings linked at the 2 and 5 positions.


IPQVWRDWFKLP

A twelve-membered polypeptide comprising the sequence Ile-Pro-Gln-Val-Trp-Arg-Asp-Trp-Phe-Lys-Leu-Pro.


A macromolecule consisting of 10-formyltetrahydrofolic acid with an arbitrary number of glutamate residues attached as a polypeptide to the single existent one.


A macromolecule composed of repeating 2-(dimethylamino)ethyl isobutyrate units.


A macromolecule composed of repeating 1-ethoxyethyl propionate units.


polystyrene macromolecule

Macromolecules composed of repeating substituted or unsubstituted ethylbenzene units.


name: S. flexneri serotype 2b O-specific polysaccharide

description: A polysaccharide derivative antigen composed of a backbone of branched hexasaccharidederivative repeating units that are joined to each other via beta-(1->2)-linkages.


A lipopolysaccharide having a 3-deoxyoctulosonyl group attached at an unspecified position.


poly(fluorene-co-phenylene)

A copolymer composed of repeating substituted or unsubstituted fluorene and phenylene units.


peptidoglycosaminoglycan

A family of glycosaminoglycan formed by alternating residues of D-glucosamine and either muramic acid {2-amino-3-O-[(S)-1-carboxyethyl]-2-deoxy-D-glucose} or L-talosaminuronic acid (2-amino-2-deoxy-L-taluronic acid), which are usually N-acetylated or N-glycoloylated. Those containing muramic acid residues are known as peptidoglycans while those containing L-talosaminuronic acid residues are known as pseudopeptidoglycans. The carboxyl group of the muramic acid is commonly substituted by a peptide containing residues of both L- and D-amino acids, whereas that of L-talosaminuronic acid is substituted by a peptide consisting of L-amino acids only.


polysaccharide derivative

A carbohydrate derivative that is any derivative of a polysaccharide.


polyhedral oligomeric silsesquioxane

A polyhedral polysilsesquioxane.


A macromolecule composed of repeating 5-(4-benzoylphenoxy)-2-hydroxybenzenesulfonic acid units.


nafion macromolecule

An ionomer macromolecule formed by incorporating perfluorovinyl ether groups terminated with sulfonate groups onto a tetrafluoroethylene (Teflon) backbone.


name: 11,13-Dihydrotaraxinic acid glucosyl ester


Major microspecies at pH 7.3


dermatan 6'-sulfate

A mucopolysaccharide consisting of dermatan with sulfate substituents at the 6'-position of the N-acetylgalactosamines.


A vinyl polymer composed of repeating -CH2-CR- units where R is a 2-pyridyl group.


polyhydroxyalkanoate

Bacteria-synthesized intracellularly accumulated polyesters from saturated and unsaturated hydroxyalkanoic acid


polyglycidol macromolecule

A macromolecule composed of repeating propane-1,2-diol units.


poly(inosinic acid)

A polynucleotide comprised of inosine units connected via 3'->5' phosphodiester linkages.


poly(3-methoxythiophene) macromolecule

A macromolecule composed of repeating 3-methoxythiophene units.


A polysaccharide derivative comprised of repeating 7,8-di-O-acetylsialyl residues, linked (2->9).


A heparin hexadecasaccharide consisting of 4-deoxy-2-O-sulfo-alpha-L-threo-hex-4-enopyranuronosyl, 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranosyl, 2-O-sulfo-alpha-L-idopyranuronosyl, 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranosyl, 2-O-sulfo-alpha-L-idopyranuronosyl, 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranosyl, 2-O-sulfo-alpha-L-idopyranuronosyl, 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranosyl, 2-O-sulfo-alpha-L-idopyranuronosyl, 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranosyl, 2-O-sulfo-alpha-L-idopyranuronosyl, 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranosyl, 2-O-sulfo-alpha-L-idopyranuronosyl, 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranosyl, 2-O-sulfo-alpha-L-idopyranuronosyl, and 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose units joined in sequence by (1->4) linkages. Sequence: DUA2S-[-GlcNS6S-IdoA2S-]7-GlcNS6S


name: P. mirabilis O6 O-specific polysaccharide

description: A polysaccharide derivative that is the capsular polysaccharide of Proteus mirabilis 06, strain ATCC 49565, consisting of a backbone of repeating derivatised-trisaccharide units.


A macromolecule composed of N-(propanamidomethyl)propanamide units.


A branched polysaccharide composed of a backbone of repeating alpha-D-Rhap-(1->3)-[beta-D-Fucf-(1->4)]-alpha-D-Rhap-(1->2)-alpha-D-Rhap units, joined by (1->3)-linkages as shown.


poly(2-oxazoline) macromolecule

A macromolecule composed of repeating acyliminoethylene units and terminated by a hydroxy group. Prepared via ring-opening polymerisation of a 2-oxazoline.


A mannan composed from D-mannan residues joined by beta-(1->4) linkages.


A polysaccharide derivative consisting of fourteen alpha-D-N-acetylneuraminyl residues joined by (2->8) linkages.


An alpha-D-glucan in which the glucose units are connected by (1->3) linkages.


poly(2,5-ethylene furandicarboxylate)

A polymer composed of 5-(ethoxycarbonyl)furan-2-carboxylic acid units.


carboxymethyl-pachyman

A polysaccharide derivative consisting of beta-D-glucopyranosyl residues linked (1->3), with approximately 20% of the residues carrying a carboxymethyl substituent at O-6. A soluble/gelatinous substrate for the assay of endo-1,3-beta-D-glucanase.


poly(propylene)

A polymer compose of repeating propane-1,2-diyl units.


A copolymer composed of unsubstituted 2,7-fluorene and 1,4-phenylene units.


A polysaccharide derivative consisting of fourteen alpha-D-N-propionylneuraminyl residues joined by (2->8) linkages.


ds/ss telomeric DNA junction

The junction formed at the point where double-stranded telomeric DNA becomes a single-stranded G-rich telomeric DNA 3' overhang.


name: S. flexneri serotype 5a O-polysaccharide (O factor 9-positive)

description: A polysaccharide derivative comprised of a [2)-alpha-L-Rhap(III)-(1->2)-alpha-L-Rhap(II)-(1->3)-alpha-L-Rhap(I)-(1->3)-beta-D-GlcpNAc-(1->] tetrasaccharide repeat modified by the (1->3) linkage of an alpha-D-glucosyl group to the Rha(II) residue and by addition of an acetyl group to either O-3 or O-4 of many of the Rha(III) residues (35% to O-3; 25% to O-4). The structure provided is representative of that in Shigella flexneri serotype 5a and shows the most common repeating unit.


A synthetic 25-membered heterodetic cyclic peptide consisting of a 14-membered linear component attached to an 11-membered cyclic portion. A CK2 inhibitor with potential antineoplastic activity.


name: Candida albicans hexasaccharide dendrimer--glycopeptide conjugate

description: A dendrimer macromolecule that is a conjugate between the tetravalent dendrimer hexasaccharide N(1),N(3)-bis[2-[bis(2-{[2-({2-[(2-{[6-(beta-D-glucopyranosyl-(1->3)-beta-D-glucopyranosyl-(1->3)-beta-D-glucopyranosyl-(1->3)-beta-D-glucopyranosyl-(1->3)-beta-D-glucopyranosyl-(1->3)-beta-D-glucopyranosyloxy)hexanoyl]amino}ethyl)amino]-3,4-dioxocyclobut-1-en-1-yl}amino)ethyl]amino}-2-oxoethyl)amino]ethyl]-2-[2-(2-{2-[(prop-2-yn-1-yl)oxy]ethoxy}ethoxy)ethyl]malonamide and the glycopeptide N-{beta-D-Man-(1->2)-beta-D-Man-(1->2)-beta-D-ManO[CH2]3S[CH2]2NHC(O)[CH2O]4C(O)[CH2]2S[CH2]2C(O)}-YGKDVKDLFDYAQE-NH-[CH2O]3[CH2]2C(O)NHC(CO2H)[CH2]4N3.


A polymer composed of repeating 1-ethyl-4-methylbenzene units.


A polysaccharide composed of a backbone of alpha-D-fucosyl (1->2)-beta-L-rhamnosyl repeating units that are joined to each other via (1->3)-linkages.


A polysaccharide derivative consisting of a backbone of L-Fucp-(1->4)-[L-Fucp-(1->3)]-L-GlcpNAc repeating units that are joined via alpha-(1->2)-linkages.


diblock copolymer

A polymer composed of two blocks of homopolymers in a linear sequence.


A mimotope of the pyruvate dehydrogenase E2 component (PDC-E2) comprising a [(2E)-3-(3-nitrophenyl)prop-2-enoyl]- group linked to the lipoated PDC-E2 core dodecapeptide (DKATIGFEVQEE) at N-6 of lysine.


chondroitin sulfate E

A chondroitin sulfate in which the site of sulfation is positions 4 and 6 of the N-acetylgalactosamine (GalNAc) sugar.


nitrocellulose

A (1->4)-beta-D-glucan compound formed by nitrating cellulose through exposure to nitric acid or another powerful nitrating agent.


xyloglucan

A glucan that consists of a backbone of alpha-(1->4)-linked glucose residues, most of which are substituted with (1->6)-linked xylose side-chains.


xanthan

Xanthan gum is a polysaccharide produced by the bacteria Xanthomonas campestris. It is composed of pentasaccharide repeat units, comprising two glucose units, two mannose units, and one glucuronic acid unit. Its main chain consists of beta-D-glucose units linked at the 1 and 4 positions. Trisaccharide side chains contain a D-glucuronic acid unit between two D-mannose units linked at the O-3 position of every other glucose residue in the main chain. Approximately one-half of the terminal D-mannose contains a pyruvic acid residue linked via keto group to the 4 and 6 positions, with an unknown distribution. D-Mannose unit linked to the main chain contains an acetyl group at position O-6.


polysaccharide

A biomacromolecule consisting of large numbers of monosaccharide residues linked glycosidically. This term is commonly used only for those containing more than ten monosaccharide residues.


A macromolecule composed of 4-(4-benzoylphenoxy)phenol units.


rRNA containing N(2)-methylguanine

A ribonucleic acid that is ribosomal RNA (rRNA) in which one of the RNA bases is N(2)-methylguanine.


dendrimer macromolecule

A highly and repetitively branched macromolecule, typically symmetric around the core, and often adopting a spherical three-dimensional morphology.


A copolymer composed of 2-hydroxyethyl 2-methylpropanoate and propanoic acid units.


Brucella sp. O-PS A-antigen

An aminoglycan composed of repeating 4,6-dideoxy-4-formamido-D-mannopyranose units joined by alpha-(1->2)-linkages.


poly(alkylene) macromolecule

A macromolecule composed of repeating alkane or substituted alkane units.


polymethylene-block-polystyrene

A diblock copolymer composed of methylene and ethyl benzene units.


galactosaminogalactan

An exopolysaccharide composed of alpha1->4 linked galactose and alpha1->4 linked N-acetylgalactosamine (GalNAc) residues where both monosacharides are randomly distributed. It is secreted by the opportunistic fungal pathogens, Aspergillus fumigatus and Aspergillus niger.


poly(alkylene oxide) macromolecule

A macromolecule composed of repeating oxyalkylene units.


KGKGKGKGKGENPAVHFFKNIVTPRTP

A linear 27-membered polypeptide comprising the sequence Lys-Gly-Lys-Gly-Lys-Gly-Lys-Gly-Lys-Gly-Glu-Asn-Pro-Ala-Val-His-Phe-Phe-Lys-Asn-Ile-Val-Thr-Pro-Arg-Thr-Pro. Corresponds to the sequence of the myelin basic protein 83-99 (MBP83-99) immunodominant epitope with the valyl residue at position 86 replaced by alanyl [MBP83-99(A(86))] and with an (L-lysylglycyl)5 [(KG5)] linker attached to the glutamine(83) (E(83)) residue.


An O-polysaccharide consisting of repeating 1,3-linked 4-O-acetyl-6-deoxy-2-O-methyl-alpha-L-talosyl-(1->3)-beta-D-glucosyl units; it forms the O-antigen repeat section of one of the lipopolysaccharides of Burkholderia pseudomallei and/or Burkholderia mallei, the etiologic agents of melioidosis and glanders, respectively.


A polysaccharide composed of a backbone of repeating alpha-L-rhamnosyl-(1->2)-alpha-L-rhamnosyl units, joined by (1->3)-linkages.


poly(D-lysine) macromolecule

A macromolecule composed of repeating D-lysyl units joined via 1,6-amide linkages.


polyfuran macromolecule

A macromolecule composed of sigma-bonded furan or substituted furan rings.


A macromolecule composed of 2,2'-bithiophene units linked at the 5- and 5'-postions.


name: S. flexneri serotype Y O-polysaccharide (O factor 9-negative)

description: A polysaccharide derivative comprised of a [2)-alpha-L-Rhap(III)-(1->2)-alpha-L-Rhap(II)-(1->3)-alpha-L-Rhap(I)-(1->3)-beta-D-GlcpNAc-(1->] tetrasaccharide repeat.


koshikamide A2

A polypeptide isolated from a marine sponge Theonella sp. and has been found to inhibit the growth of P388 murine leukemia cells.


mannan derivative

A homopolysaccharide derivative which is formally derived from a mannan.


name: P. mirabilis 9B-m O-specific polysaccharide

description: A polysaccharide derivative consisting of a repeating unit of beta-D-glucuronosyl, beta-D-galacturonosyl and N-acetyl-beta-D-glucosaminyl residues linked sequentially (1->3) and (1->3), to the glucuronosyl residue of which is linked (1->2) an N-acetyl-beta-D-glucosaminyl residue, while the galacturonosyl residue forms an amide with L-threonine, the complete tetrasaccharide repeating units all being linked (1->4). The O-polysaccharide of Proteus mirabilis 9B-m.


name: P. mirabilis O23 O-deacetylated O-specific polysaccharide

description: The O-deacetylated polysaccharide antigen from P. mirabilis O23 consisting of a backbone of linear tetrasaccharide repeating units that are joined head-to-tail via alpha-(1->4)-linkages.


A branched amino oligosaccharide that is an undecasaccharide derivative in which two alpha-L-fucosyl-(1->3)-[beta-D-galactosyl-(1->4)]-N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl tetrasaccharide units are linked (1->3) and (1->6) to the mannose residue of a beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl(1->4)-N-acetyl-D-glucosamine trisaccharide.


A 39-membered polypeptide consisting of His, Ser, Asp, Gly, Thr, Phe, Thr, Ser, Asp, Leu, Ser, Lys, Gln, Met, Glu, Glu, Glu, Ala, Val, Arg, Leu, Phe, Ile, Glu, Trp, Leu, Lys, Asn, Gly, Gly, Pro, Ser, Ser, Gly, Ala, Pro, Pro, Pro and Ser-NH2 residues joined in sequence. It is isolated from venom of the Gila monster lizard Heloderma horridum.


poly(diiododiacetylene) macromolecule

A macromolecule composed of repeating 1,2-diiodobut-1-en-3-yne units.


name: S. flexneri serotype 2a O-specific polysaccharide

description: A polysaccharide derivative antigen composed of a backbone of branched, derivatised-pentasaccharide repeating units that are joined to each other via beta-(1->2)-linkages.


name: deuterated poly(methyl methacrylate) macromolecule

description: A macromolecule composed of repeating methyl methacrylate units in which some of the hydrogen atoms have been replaced by deuterium atoms.


poly(oxymethylene) macromolecule

A poly(alkylene oxide) macromolecule, composed of repeating methyleneoxy units.


poly(methylene)

A polymer composed of repeating CH2 units.


lipid-linked peptidoglycan

A peptidoglycan with a phosphate linkage to a lipid.


A branched polysaccharide composed of a backbone of repeating alpha-D-Rhap-(1->3)-[beta-D-Fucf-(1->4)]-alpha-D-Rhap-(1->2)-alpha-D-Rhap-(1->2)-alpha-D-Rhap units, joined by (1->3)-linkages as shown.


compound 48/80

R1, R2 = H or CH2OH; n is normally between 1 and 10. An alternating copolymer resulting from the condensation of N,O-dimethyltyramine with formaldehyde. It is a potent histamine releasing agent, primarily from mast cells, with subsequent depletion of tissue histamine.


carboxymethylcellulose

A polysaccharide derivative that is cellulose in which carboxymethyl groups are bound to some of the hydroxyl groups of the glucopyranose monomers.


name: poly(glucosyl N-acetylgalactosamine 1-phosphate) teichoic acid

description: One of the teichoic acids found in the cell wall of Gram-positive bacteria.


poly(2,7-carbazole) macromolecule

A macromolecule composed of repeating 2,7-linked substituted or unsubstituted carbazole units.


poly(vinylethylene) macromolecule

A macromolecule composed of repeating 1-vinylethylene units.


tetracosactide

A synthetic peptide that is identical to the 24-amino acid segment at the N-terminal of adrenocorticotropic hormone (corticotropin). A segment similar in all species, it contains the biological activity that stimulates production of corticosteroids in the adrenal cortex. It is used diagnostically to investigate adrenocortical insufficiency.


rRNA containing 2'-O-methyladenosine

A ribonucleic acid that is ribosomal RNA (rRNA) in which one of the RNA nucleotides is 2'-O-methyladenosine 5'-monophosphate.


A macromolecule composed of repeating ethoxyethyl propionate units.


A polymer composed of repeating 3-hydroxybutyryl units.


polyphenylene ethynylene macromolecule

A homopolymer macromolecule, composed of alternating phenylene and ethynediyl units.


A macromolecule composed of repeating 9,9'-dioctylfluorene-2,7-diyl units.


poly(dichlorophosphazene) macromolecule

A polphosphazene macromolecule composed of repeating dichlorophosphazene (-PCl2=N-) units.


phosphotungstic acid macromolecule

A heteropolyacid macromolecule with the formula H3PW12O40.


heparin hexadecasaccharide

Any heparin oligosaccharide consisting of 16 glycosidically linked monosaccharide residues.


A polypeptide mimotope of the pyruvate dehydrogenase E2 component (PDC-E2) comprising a 2-(trifluoromethyl)benzoyl group linked to the lipoated PDC-E2 core dodecapeptide (DKATIGFEVQEE) at N-6 of lysine.


graft polymer macromolecule

A macromolecule, in which the backbone chain has attached to it, at various points along the chain, groups or atoms, which are different from those found in the main chain.


poly(butyl acrylate) macromolecule

A macromolecule composed of repeating butyl propionate units.


bacitracin A zwitterion

A homodetic cyclic peptide consisting of (4R)-2-[(1S,2S)-1-amino-2-methylbutyl]-4,5-dihydro-1,3-thiazole-4-carboxylic acid attached head-to-tail to L-leucyl,D-glutamyl, L-lysyl, D-ornityl, L-isoleucyl, D-phenylalanyl, L-histidyl. D-aspartyl and L-asparaginyl residues coupled in sequence and cyclised by condensation of the side-chain amino group of the L-lysyl residue with the C-terminal carboxylic acid group. It is the major component of bacitracin.


poly(melamine) macromolecule

A macromolecule composed of repeating 1,3,5-triazine-2,4,6-triamine units.


A copolymer of beta-D-arabinofuranosyl-(1->2)-alpha-D-arabinofuranosyl-(1->3)-[beta-D-arabinofuranosyl-(1->2)-alpha-D-arabinofuranosyl-(1->5)]-alpha-Darabinofuranosyl-(1->5)-alpha-D-arabinofuranoside and copovidone and comprised of N-(2-{[beta-D-arabinofuranosyl-(1->2)-alpha-D-arabinofuranosyl-(1->3)-[beta-D-arabinofuranosyl-(1->2)-alpha-D-arabinofuranosyl-(1->5)]-alpha-D-arabinofuranosyl-(1->5)-alpha-D-arabinofuranosyl]oxy}octyl)-N'-[(1-vinyl-1H-1,2,3-triazol-4-yl)methyl]pentanediamide, vinyl alcohol and N-vinyl-2-pyrrolidone units.


suberin

A complex lipophilic polymer macromolecule, containing a fatty acid-derived domain (aliphatic suberin) and a (poly)hydroxycinnamate domain (aromatic suberin).


A mimotope of the pyruvate dehydrogenase E2 component (PDC-E2) comprising a chloroacetyl group linked to the lipoated PDC-E2 core dodecapeptide (DKATIGFEVQEE) at N-6 of lysine.


hexa-L-lysine monohydrobromide

A compound comprising six covalently linked L-lysine residues ionically bound to hydrogen bromide.


glycopolymer macromolecule

A macromolecule containing saccharide side-groups.


A mimotope of the pyruvate dehydrogenase E2 component (PDC-E2) comprising a 2-iodobenzoyl group linked to the lipoated PDC-E2 core dodecapeptide (DKATIGFEVQEE) at N-6 of lysine.


A glycosylglycerol derivative in which the glycosyl moiety of glycosyl-sn-glycerol is N-acetyl-beta-D-glucosaminyl-(1->3)-[(D-glyceric acid)-(2->1)]-beta-D-glucosaminyl-(6-phospho-6)-N-acetyl-beta-D-glucosaminyl-(1->3)-[(D-glyceric acid)-(2->1)]-beta-D-glucosaminyl-(6-phospho-6)-beta-D-glucosyl-(1->6)-beta-D-glucosyl-(1->6)-beta-D-glucosyl attached at O-3, with O-1 and O-2 both carrying myristoyl substituents. Synthetic C. difficile lipoteichoic acid (LTA) molecule consisting of lipid + core region and two [(->6)-alpha-D-GlcpNAc-(1->3)-[P-6]-alpha-D-GlcpNAc-(1->2)-D-GroA polymeric repeats (where P-6 is a phosphodiester bridge and GroA is glyceric acid).


poly(lysine) macromolecule

A macromolecule composed of repeating lysyl units joined via 1,6-amide linkages.


colestipol

A high molecular weight copolymer of diethylenetriamine and epichlorohydrin (hydrochloride), with approximately 1 out of 5 amine nitrogens protonated. Due to the highly cross-linked and insoluble nature of the material, no structural formula has been assigned and no specific molecular weight information is available. A basic anion exchange resin, it is used as its hydrochloride for binding bile acids in the intestine, inhibiting their reabsorption.


polythiophene macromolecule

Macromolecules composed of thiophene or substituted thiophene units.


keratan 6'-sulfate

A keratan sulfate with random sulfation at the 6'-position.


An O-polysaccharide consisting of repeating 1,3-linked 6-deoxy-alpha-L-talosyl-(1->3)-beta-D-glucosyl units; it forms the O-antigen repeat section of one of the lipopolysaccharides of Burkholderia pseudomallei and/or Burkholderia mallei, the etiologic agents of melioidosis and glanders, respectively.


polyfluorene macromolecule

A macromolecule composed of repeating substituted or unsubstituted fluorene units.


enfuvirtide

A synthetic 36-amino acid peptide consisting of  N-acetyltyrosyl, threonyl, seryl, leucyl, isoleucyl, histidyl, seryl, leucyl, isoleucyl, alpha-glutamyl, alpha-glutamyl, seryl, glutaminyl, asparaginyl, glutaminyl, glutaminyl, alpha-glutamyl, lysyl, asparaginyl, alpha-glutamyl, alpha-glutamyl, alpha-glutamyl, leucyl, leucyl, alpha-glutamyl, leucyl, alpha-aspartyl, lysyl, tryptophyl, alanyl, seryl, leucyl, tryptophyl, asparaginyl, tryptophyl, and phenylalaninamide residues joined in sequence. An HIV fusion inhibitor, it was the first of a novel class of antiretroviral drugs used in combination therapy for the treatment of HIV-1 infection. It interferes with entry of HIV into cells by binding to the gp41 sub-unit of the viral envelope glycoprotein, so inhibiting fusion of viral and cellular membranes.


An acrylate macromolecule, composed of repeating 2-hydroxyethyl 2-methylpropanoate units.


teichoic acid

Bacterial polysaccharide derivatives of glycerol phosphate or ribitol phosphate linked via phosphodiester bonds, whose main function is to fortify the cell wall. In some parasites, they serve as a site of attachment to mucosal membranes.


poly(D,L-lactic acid-co-glycolic acid)

A copolymer composed of 2-hydroxypropanoyl and 2-hydroxyacetyl units.


A polysaccharide composed of a backbone of repeating alpha-D-rhamnosyl-(1->3)-alpha-D-rhamnosyl-(1->2)-alpha-D-rhamnosyl-(1->2)-alpha-D-rhamnosyl units, joined by (1->3)-linkages


alginic acid

A linear copolymer macromolecule composed of homopolymeric blocks of 1->4-linked beta-D-mannuronic acid and alpha-L-guluronic acid residues, covalently linked together in different sequences or blocks.


enterobacterial common antigen

An acidic polysaccharide containing N-acetyl-D-glucosamine, N-acetyl-D-mannosaminouronic acid, and 4-acetamido-4,6-dideoxy-D-galactose. A major component of the cell wall outer membrane of Gram-negative bacteria.


biomacromolecule

A macromolecule formed by a living organism.


amylodextrin

A linear dextrin or short chained amylose (DP 20-30) that can be produced by enzymatic hydrolysis of the alpha-1,6 glycosidic bonds or debranching amylopectin.


A glycosylglycerol derivative in which the glycosyl moiety of glycosyl-sn-glycerol is N-acetyl-beta-D-glucosaminyl-(1->3)-[(D-glyceric acid)-(2->1)]-beta-D-glucosaminyl-(6-phospho-6)-beta-D-glucosyl-(1->6)-beta-D-glucosyl-(1->6)-beta-D-glucosyl attached at O-3, with O-1 and O-2 both carrying myristoyl substituents. Synthetic C. difficile lipoteichoic acid (LTA) molecule consisting of lipid + core region and one [(->6)-alpha-D-GlcpNAc-(1->3)-[P-6]-alpha-D-GlcpNAc-(1->2)-D-GroA polymeric repeat (where P-6 is a phosphodiester bridge and GroA is glyceric acid).


S. flexneri Y polysaccharide

A bacterial polysaccharide derivative composed of a backbone of tetrasaccharide derivative repeating units that are joined to each other via beta-(1->2)-linkages.


homopolysaccharide

Glycans composed of a single type of monosaccharide residue. They are named by replacing the ending '-ose' of the sugar by '-an'.


poly(alkoxythiophene) macromolecule

A macromolecule composed of repeating alkoxythiophene units.


An amino oligosaccharide that is a branched tridecasaccharide in which two beta-D-Gal-(1->4)-beta-D-GlcNAc disaccharide units are linked (1->2) and (1->4) to the terminal mannose residue of an alpha-D-Man-(1->3)-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc tetrasaccharide chain, to the beta-D-mannose residue of which is also linked (1->6) a beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-alpha-D-Man trisaccharide unit.


An amino oligosaccharide that is a branched dodecasaccharide derivative comprising N-acetylneuraminic acid, D-galactose, N-acetyl-D-glucosamine and D-mannoseD residues linked as shown. It constitutes the N-glycan moiety in human thyroglobulin.


poly(tetrafluoroethylene)

A polymer composed of repeating tetrafluoroethyl groups.


cyclomaltodextrin

A cyclic oligosaccharide comprising a ring of D-glucose units linked by alpha-(1->4) glycosidic bonds.


dextrin

Glucans produced by the hydrolysis of starch or glycogen. They are mixtures of polymers of D-glucose units linked by alpha(1->4) or alpha(1->6) glycosidic bonds.


xylan

Polysaccharides composed of xylose residues.


poly(ethylene terephthalate)(1-)

An ionic polymer resulting from the deprotonation of the terminal carboxy groups of poly(ethylene terephthalate) polymer.


poly(m-divinylbenzene) macromolecule

A macromolecule composed of repeating m-phenylenediethylene units.


A macromolecule composed of repeating 3,4-ethylenedioxythiophenyl units.


tactic macromolecule

A macromolecule with regularity or symmetry in the structural arrangement of its monomers.


name: S. flexneri serotype 2a O-polysaccharide (O factor 9-negative)

description: A polysaccharide derivative comprised of a [2)-alpha-L-Rhap(III)-(1->2)-alpha-L-Rhap(II)-(1->3)-alpha-L-Rhap(I)-(1->3)-beta-D-GlcpNAc-(1->] tetrasaccharide repeat modified by the (1->4) linkage of an alpha-D-glucosyl group to the Rha(I) residue and by addition of an acetyl group to 50% of the O-6 positions of the GlcNAc residue. The structure provided is representative of that in Shigella flexneri serotype 2a and shows the repeating unit containing the acetyl group on the GlcNAc residue.


A ionic polymer obtained by global deprotonation of the phosphate OH groups of any RNA linked to an uridine ribonucleotide in 3'; major structure at pH 7.3.


poly(butylene oxide) macromolecule

A macromolecule composed of repeating oxybutylene units.


ENPVVAFFKNIVTPRTP

A linear seventeen-membered polypeptide comprising the sequence Glu-Asn-Pro-Val-Val-Ala-Phe-Phe-Lys-Asn-Ile-Val-Thr-Pro-Arg-Thr-Pro. Corresponds to the sequence of the myelin basic protein 83-99 (MBP83-99) immunodominant epitope with the histidyl residue at position 88 replaced by alanyl [MBP83-99(A(88))].


beta-limit dextrin

beta-Limit dextrin is the remaining polymer produced by enzymatic hydrolyse of amylopectine with beta amylase which cannot hydrolyse the alpha-1,6 bonds at branch points.


A heparin icosasaccharide consisting of 4-deoxy-2-O-sulfo-L-threo-hex-4-enopyranuronosyl, 2-deoxy-6-O-sulfo-2-(sulfoamino)-D-glucopyranosyl, 2-O-sulfo-L-idopyranuronosyl, 2-deoxy-6-O-sulfo-2-(sulfoamino)-D-glucopyranosyl, 2-O-sulfo-L-idopyranuronosyl, 2-deoxy-6-O-sulfo-2-(sulfoamino)-D-glucopyranosyl, 2-O-sulfo-L-idopyranuronosyl, 2-deoxy-6-O-sulfo-2-(sulfoamino)-D-glucopyranosyl, 2-O-sulfo-L-idopyranuronosyl, 2-deoxy-6-O-sulfo-2-(sulfoamino)-D-glucopyranosyl,2-O-sulfo-L-idopyranuronosyl, 2-deoxy-6-O-sulfo-2-(sulfoamino)-D-glucopyranosyl, 2-O-sulfo-L-idopyranuronosyl, 2-deoxy-6-O-sulfo-2-(sulfoamino)-D-glucopyranosyl, 2-O-sulfo-L-idopyranuronosyl, 2-deoxy-6-O-sulfo-2-(sulfoamino)-D-glucopyranosyl, 2-O-sulfo-L-idopyranuronosyl, 2-deoxy-6-O-sulfo-2-(sulfoamino)-D-glucopyranosyl, 2-O-sulfo-L-idopyranuronosyl, and 2-deoxy-6-O-sulfo-2-(sulfoamino)-D-glucopyranose units joined in sequence by alpha-(1->4) linkages. Sequence: DUA2S-(1-4)-a-D-GlcNS6S-(1-4)-a-L-IdoA2S-(1-4)-a-D-GlcNS6S-(1-4)-a-L-IdoA2S-(1-4)-a-D-GlcNS6S-(1-4)-a-L-IdoA2S-(1-4)-a-D-GlcNS6S-(1-4)-a-L-IdoA2S-(1-4)-a-D-GlcNS6S-(1-4)-a-L-IdoA2S-(1-4)-a-D-GlcNS6S-(1-4)-a-L-IdoA2S-(1-4)-a-D-GlcNS6S-(1-4)-a-L-IdoA2S-(1-4)-a-D-GlcNS6S-(1-4)-a-L-IdoA2S-(1-4)-a-D-GlcNS6S-(1-4)-a-L-IdoA2S-(1-4)-a-D-GlcNS6S.


poly(styrene)

A polymer composed of repeating ethyl benzene groups.


rRNA containing C(5)-methyluridine

A ribonucleic acid that is ribosomal RNA (rRNA) in which one of the RNA bases is 5-methyluridine.


A mimotope of the pyruvate dehydrogenase E2 component (PDC-E2) comprising a (2,2,2-trifluoroethoxy)acetyl group linked to the lipoated PDC-E2 core dodecapeptide (DKATIGFEVQEE) at N-6 of lysine.


A macromolecule composed of repeating triethyl({3-[(4-methylthiophen-3-yl)oxy]propyl})azanium chloride units.


poly(norbornene) macromolecule

A macromolecule composed of repeating substituted or unsubstituted vinylcyclopentane units.


GlyTouCan G70101JE

A partially-defined glycan consisting of nine hexosyl and two acetaminohexosyl groups (identities and connectivity unknown). Composition: Hex9 HexNAc2.


lignocellulose

A complex biopolymer that is a component of plant cell walls which is used as a renewable feedstock for the production of paper, fuels, and chemicals (also used as a feed supplement in the poultry industry). Its structure comprises of three main types of carbon-based polymer -- cellulose, hemicellulose and lignin. Generally, its biomass consists of 35-50% cellulose, 20-35% hemicellulose, and 10-25% lignin with proteins, oils, and ash making up the remaining fraction.


A polysaccharide derivative comprising a tetrasaccharide repeating unit consisting of a trisaccharide backbone of beta-D-galactosyl, beta-D-glucosyl and N-acetyl-beta-D-glucosaminyl residues linked sequentially (1->4) and (1->6), with a further beta-D-galactosyl residue linked (1->4) to the N-acetyl-beta-D-glucosaminyl residue, and with the tetrasaccharide repeats themselves being linked (1->3); corresponds to the serotype 14 capsular polysaccharide (CPS) of Streptococcus pneumoniae. The structure diagram shows a portion of the polysaccharide chain consisting of three such tetrasaccharide repeating units showing clearly the (1->3) linkages existing between the repeating units.


vinyl polymer macromolecule

A macromolecule composed of repeating -CHR-CH2- units.


polyvinyl alcohol

A homopolymer macromolecule obtained by polymerisation of vinyl alcohol.


A synthetic 28-amino acid polypeptide consisting of glutaminyl, seryl, prolyl, seryl, tyrosyl, prolyl, alpha-aspartyl, arginyl, alpha-glutamyl, tyrosyl, seryl, alpha-aspartyl, alpha-glutamyl, alpha-aspartyl, arginyl, glutaminyl, isoleucyl, lysyl, glutaminyl, methionyl, leucyl, histidyl, glutaminyl, alpha-glutamyl, cysteinyl, prolyl, arginyl and leucinamide residues joined in sequence. A synthetic version of the peptide epitope from the major peanut allergen glycoprotein Arachis hypogaea h2 (Ara-h2).


A macromolecule composed of repeating 2-ethoxyethyl propionate units.


name: S. flexneri serotype 1b O-polysaccharide (O factor 9-positive)

description: A polysaccharide derivative comprised of a [2)-alpha-L-Rhap(III)-(1->2)-alpha-L-Rhap(II)-(1->3)-alpha-L-Rhap(I)-(1->3)-beta-D-GlcpNAc-(1->] tetrasaccharide repeat modified by the (1->4) linkage of an alpha-D-glucosyl group to the GlcNAc residue and by addition of acetyl groups to O-2 of 80% of the Rha(I) residues and to either O-3 or O-4 of many of the Rha(III) residues (70% to O-3; 15% to O-4). The structure provided is representative of that in Shigella flexneri serotype 1b and shows the most common repeating unit.


poly(uridylic acid)

A polynucleotide comprised of uridine units connected via 3'->5' phosphodiester linkages.


poly(p-dioxane) macromolecule

A macromolecule composed of repeating 2-ethoxyethanol units.


A macromolecule composed of repeating N-(1,1,2,2,3,3-hexafluorobutyl)-2-methylpropanamide units.


A macromolecule composed of repeating gamma-linked L-glutamyl units.


poly(ferrocenylene) macromolecule

A polymetallocene macromolecule composed of repeating bis(eta5-cyclopentadienyl)iron units.


galactan derivative

A homopolysaccharide derivative which is formally derived from a galactan.


A poly(hydroxybutyrate) composed of repeating (R)-3-hydroxybutyryl units.


DNA random copolymer

A random copolymer in which the monomeric units are DNA nucleotide residues.


name: S. Pullorum strain 77 O-specific polysaccharide

description: A polysaccharide composed of a backbone of branched pentasaccharide repeating units that are joined to each other via alpha-(1->2)-linkages.


A bioactive polypeptide of 39 amino acid residues isolated from the saliva of the Gila monster (Heloderma suspectum). High-affinity glucagon-like peptide 1 (GLP-1) receptor agonist (Kd = 136 pM); potently induces cAMP formation without stimulating amylase release in pancreatic acini; potentiates glucose-induced insulin secretion in isolated rat islets; protects against glutamate-induced neurotoxicity. A synthetic version is called exenatide.


poly(vinylpyridine)

A vinyl polymer composed of repeating -CH2-CR- units where R is a pyridyl group.


poly(amide) macromolecule

A polymer composed of units connected by amide (-NR-C(=O)-) linkages, where R can be H or organyl.


beta-endorphin

A polypeptide consisting of 31 amino acid residues in the sequence Tyr-Gly-Gly-Phe-Met-Thr-Ser-Glu-Lys-Ser-Gln-Thr-Pro-Leu-Val-Thr-Leu-Phe-Lys-Asn-Ala-Ile-Ile-Lys-Asn-Ala-Tyr-Lys-Lys-Gly-Glu.  It is an endogenous opioid peptide neurotransmitter found in the neurons of both the central and peripheral nervous system and results from processing of the precursor protein proopiomelanocortin (POMC).


A (1->4)-beta-D-glucan compound composed of repeating beta-(1->4)-linked 6-azido-6-deoxyglucose units.


A polysaccharide derivative with a repeating unit consisting of alpha-D-galactosyl, 2-O-acetyl-beta-L-rhamnosyl, beta-D-glucosyl and N-acetyl-beta-D-galactosaminyl residues linked sequentially (1->3), (1->4) and (1->3), to the galactosyl and N-acetyl-beta-D-galactosaminyl residues of which are attached respectively a beta-D-galactosyl residue and an N-acetyl-alpha-D-glucosaminyl-(1->2)-alpha-L-rhamnosyl disaccharide unit via (1->2) and (1->4) linkages respectively, with all repeating units being linked (1->6). The repeating unit corresponds to that of the capsular polysaccharide of Streptococcus pneumoniae serotype 7F (ST7F).


poly(aryleneethynylene) macromolecule

A macromolecule containing alternating arylene and ethynylene repeating units.


mastoparan-V

A member of the class of mastopyrans that is a 14-amino acid polypeptide comprising isoleucyl, asparaginyl, tryptophyl, lysyl, glycyl, isoleucyl, alanyl, alanyl, methionyl, alanyl, lysyl, lysyl, leucyl, and leucinamide residues coupled in sequence. It is the major active component of the venom of the hornet Vespa velutina and causes degranulation of mast cells. It exhibits antimicrobial activity against both Gram-positive and -negative bacteria as well as haemolytic activity on chicken, human and sheep erythrocytes.


poly(ether-sulfone) macromolecule

A poly(sulfone) macromolecule composed of units connected by alternating sulfonyl (-SO2-) and ether (-O-) linkages.


poly(alkylene vinylene) macromolecule

A macromolecule with the general formula (-CR2-CR=C(R)CR2-)n where R=H or an alkyl group.


A polysaccharide derivative comprising a trisaccharide repeating unit consisting of three alpha-L-rhamnosyl residues linked sequentially (1->3) and (1->3), with the trisaccharide repeats themselves being linked (1->2); a main component of Pseudomonas aeruginosa A-band polysaccharide (A-PS).


small nucleolar RNA

A group of non-coding RNAs that primarily accumulate in the nucleoli and consist of 60-300 nucleotides. They are responsible for the post-transcriptional modification and maturation of ribosomal RNAs (rRNAs), small nuclear RNAs (snRNAs), and other cellular RNAs. There are two main classes of snoRNA, the C/D box snoRNAs, which are associated with methylation, and the H/ACA box snoRNAs, which are associated with pseudouridylation.


A diblock copolymer composed of adjacent blocks of poly(methyl methacrylate) and polystyrene.


name: S. flexneri serotype 5a O-specific polysaccharide

description: A polysaccharide derivative antigen composed of a backbone of branched pentasaccharide derivative repeating units that are joined to each other via beta-(1->2)-linkages.


poly[d(GGA)]

A single-stranded DNA polynucleotide consisting of a repeating sequence of two deoxyguanosine residues and one deoxycytosine residue, with all residues connected by 3'->5' phosphodiester linkages.


An amino oligosaccharide that is a branched undecasaccharide derivative consisting of a heptasaccharide chain of alpha-sialyl, beta-D-galactose, N-acetyl-beta-D-glucosamine, alpha-D-mannose, beta-D-mannose, and two N-acetyl-beta-D-glucosamine residues linked sequentially (2->3), (1->4), (1->2), (1->3), (1->4) and (1->4), to the beta-D-mannose residue of which is (1->6)-linked a beta-D-galactosyl-(1->4)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->3)-alpha-D-mannosyl tetrasaccharide branch and to the reducing end N-acetyl-beta-D-glucosamine residue of which is (1->6)-linked an alpha-L-fucose residue. When it is the N-glycan content of the tumour necrosis factor (TNF) alpha blocker cetuximab, the terminal Neu5Ac residue may be replaced by Neu5Gc, while the fucose residue may be absent. When it is the N-glycan content of the tumour necrosis factor (TNF) alpha blocker infliximab, the terminal Neu5Ac residue may be replaced by Neu5Gc, while one or both of the fucose and terminal galactose residues may be absent.


abarelix

A polypeptide compound composed of ten natural and non-natural amino acid resiudes in a linear sequence.


A branched polysaccharide derivative composed of a backbone of repeating beta-D-Glc-(1->6)-[alpha-D-NeuNAc-(2->3)-beta-D-Gal-(1->4)]-beta-D-GlcNAc-(1->3)-beta-D-Gal units, joined by (1->4)-linkages as shown.


threose nucleic acid

Nucleic acids that have threose instead of ribose or deoxyribose in their sugar-phosphate backbones.


A polyphenylene ethynylene macromolecule, composed of repeating 4-ethynylphenyl groups.


A glucan derivative that consists of a (1->4)-beta-D-glucan moiety attached at position 1 of any ceramide via a glycosidic linkage.


peptide nucleic acid

Nucleic acids where the sugar-phosphate backbone has been replaced by a neutral polyamide backbone such as N-(2-aminoethyl)glycine units.


mucopolysaccharide

Any of the group of polysaccharides composed of alternating units from uronic acids and glycosamines, and commonly partially esterified with sulfuric acid.


ghrelin

A 28-membered appetite-stimulating polypeptide consisting of Gly, Ser, Ser(octanoyl), Phe, Leu, Ser, Pro, Glu, His, Gln, Arg, Val, Gln, Gln, Arg, Lys, Glu, Ser, Lys, Lys, Pro, Pro, Ala, Lys, Leu, Gln, Pro and Arg residues joined in sequence. The O-n-octanoylation of the side-chain hydroxy group of serine-3 (Ser3) is essential for ghrelin's activity.


ENPVVHFFKNIVTPRTP

A linear seventeen-membered polypeptide comprising the sequence Glu-Asn-Pro-Val-Val-His-Phe-Phe-Lys-Asn-Ile-Val-Thr-Pro-Arg-Thr-Pro. Corresponds to the sequence of the myelin basic protein 83-99 (MBP83-99) immunodominant epitope.


U1 small nuclear RNA

The small nuclear RNA (snRNA) that is a component of U1 snRNP (small nuclear ribonucleoprotein), an RNA-protein complex that combines with other snRNPs, unmodified pre-mRNA, and various other proteins to assemble a spliceosome, a large RNA-protein molecular complex upon which splicing of pre-mRNA occurs.


glucan

A polysaccharide composed of glucose residues.


leucoemeraldine macromolecule

A macromolecule composed of aniline units connected by amine bonds.


poly(N-vinylimidazole) macromolecule

A macromolecule composed of repeating 1-ethylimidazole units.


An aminoglycan consisting of a poly[(1->4)-N-acetyl-beta-D-glucosaminyl] chain attached at position 4 of N-acetyl-2-deoxy-2-amino-D-glucono-1,5-lactone via a glycosidic linkage. Chitin or cellulose lysed  by an LPMO.


ENPVVHFFYNIVTPRTP

A linear seventeen-membered polypeptide comprising the sequence Glu-Asn-Pro-Val-Val-His-Phe-Phe-Tyr-Asn-Ile-Val-Thr-Pro-Arg-Thr-Pro. Corresponds to the sequence of the myelin basic protein 83-99 (MBP83-99) immunodominant epitope with the lysyl residue at position 91 replaced by tyrosyl [MBP83-99(Y(91))].


chitosan

An aminoglycan consisting of beta-(1->4)-linked D-glucosamine residues.


A branched polysaccharide derivative composed of a backbone of repeating [alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->6)]-beta-D-Glc-(1->4)-[beta-D-Glc-(1->3)]-beta-D-Gal-(1->4)-beta-D-Glc units, joined by (1->4)-linkages as shown.


A polysaccharide derivative with a repeating unit consisting of beta-D-galactosyl, beta-D-rhamnoosyl and beta-D-glucosyl residues all linked (1->4), to the galactosyl residue of which is attached an N-acetyl-alpha-neuraminyl-(2->6)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl trisaccharide unit via a (1->3) linkage, while to the rhamnosyl residue is linked (1->3) an alpha-D-galactosyl residue, with all repeating units being linked (1->4). Capsular polysaccharide of Streptococcus suis serotype 2.


poly(carbazole-2,7-diyl) macromolecule

A macromolecule composed of repeating 2,7-linked carbazole units.


polyarylene macromolecule

A macromolecule, composed exclusively of repeating arylene or heteroarylene units.


linear maltodextrin

A maltodextrin in which the alpha-(1->4)-linked D-glucose units form a linear chain, typically from 3 to 17 glucose units long. (Cf. amylose, in which the chain length ranges from around 300 to several thousand glucose units).


poly(acrylamide) macromolecule

A macromolecule composed of repeating 1-carbamoylethylene units.


poly(triphenylamine) macromolecule

A macromolecule composed of repeating N(Ph)3 units.


poly(hydroxyvalerate)

A polymer composed of repeating hydroxypentanoyl units.


YIIKGLFWDPAC

A twelve-membered polypeptide comprising the sequence Tyr-Ile-Ile-Lys-Gly-Leu-Phe-Trp-Asp-Pro-Ala-Cys. Corresponds to the P34166[24-35] fragment of mating hormone A-factor 2 from Saccharomyces cerevisiae (strain ATCC 204508/S288c).


A branched amino octasaccharide consisting of a beta-D-GlcNAc residue at the reducing end with a beta-D-GalNAc-(1->4)-beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)-[alpha-D-Man-(1->3)]-[beta-D-Xyl-(1->2)]-beta-D-Man-(1->4)-beta-D-GlcNAc moiety attached via a beta-(1->4)-linkage.


A member of the class of  triazoles that is 1-phenyl-1H-1,2,4-triazole substituted by 2-hydroxyphenyl groups at positions 3 and 5.


name: Solasodine base + 2H, 1O, O-Hex-Hex-Hex-Pen


A polythiophene polymer, composed of poly{3-[(S)-5-amino-5-carboxyl-3-oxapentyl]-2,5-thiophenylene hydrochloride} macromolecules.


1-(alk-1-enyl)-sn-glycero-3-phosphoethanolamine zwitterion in which the alk-1-enyl group is specified as octadec-1-enyl.


3-(methylsulfanyl)propanal oxime

An aliphatic aldoxime resulting from the formal condensation of 3-(methylsulfanyl)propanal with hydroxylamine.


lead tetraacetate

An acetate salt with formula Pb(OAc)4. It is used as a selective oxidising agent in organic synthesis.


An alkyl,acyl-sn-glycero-3-phosphoethanolamine zwitterion in which the alkyl or acyl groups at positions 1 and 2 contain a total of 40 carbons and 4 double bonds.


name: acetic acid [3-oxo-2-(trifluoromethyl)-4H-1,4-benzoxazin-2-yl] ester


A quercetin O-glycoside that consists of quercetin substituted by a alpha-L-rhamnopyranosyl(1->6)-beta-D-galactopyranosyl residue at position 7 via a glycosidic linkage. Isolated from Grevillea, it exhibits antimalarial activity.


magnesium citrate

A magnesium salt composed of magnesium and citrate ions in a 3:2 ratio.


sulfoethanethioaldehyde

Major microspecies at pH 7.3.


phosphatidylethanolamine 46:1

A 1,2-diacyl-sn-glycero-3-phosphoethanolamine zwitterion in which the acyl groups at C-1 and C-2 contain 46 carbons in total with 1 double bond.


tungsten cation

A generic term for all the possible tungsten cations (W6+, W4+, etc...)


A trisaccharide derivative that consists of 6-sulfated D-glucose having an alpha-L-fucosyl residue attached at position 3 and a beta-D-galactosyl residue attached at position 4.


beta-D-Galp-(1->4)-[alpha-L-Fucp-(1->3)]-D-Glcp6S in which the anomeric configuration of the glucose residue is beta.


leukoaminochrome

A member of the class of indoles that is indoline with hydroxy substituents at positions 5 and 6.


name: 5-hydroxy-2-(phenoxymethyl)-3-benzofurancarboxylic acid ethyl ester


A ceramide obtained by formal condensation of the carboxy group of tricosanoic acid with the amino group of (4E,14Z)-sphinga-4,14-dienine.


name: 2-[(3-methyl-6-oxo-7,8,9,10-tetrahydrobenzo[c][1]benzopyran-2-yl)oxy]acetic acid ethyl ester


name: 2-(1H-benzimidazol-2-ylthio)acetic acid methyl ester


A 1,2-diacyl-sn-glycero-3-phospho-N-methylethanolamine zwitterion in which the phosphatidyl acyl groups are both specified as oleoyl (9Z-octadecenoyl); major species at pH 7.3.


A fluorophenol that is phenol in which the hydrogen para- to the hydroxy group has been replaced by a fluorine.


A 1,2-diacyl-sn-glycero-3-phosphoethanolamine zwitterion in which the acyl groups at C-1 and C-2 contain 38 carbons in total with 0 double bonds.


L-phenylalanine 2-naphthylamide

An L-phenylalanine derivative that is the amide obtained by formal condensation of the carboxy group of L-phenylalanine with the amino group of 2-naphthylamine.


name: 5'-end (N(7)-methyl 5'-triphospho-guanosine)-adenosine(2-) residue

description: A 7-methyl guanosine (m7G) linked via an inverted 5'-5' triphosphate bridge to an initiating adenosine nucleotide; major species at pH 7.3.


A 7-methyl guanosine (m7G) linked via an inverted 5'-5' triphosphate bridge to an initiating ribonucleoside


A 7-methyl guanosine (m7G) linked via an inverted 5'-5' triphosphate bridge to an initiating purine ribonucleotide


name: 5'-end (N(7)-methyl 5'-triphospho-guanosine)-guanosine(2-) residue

description: A 7-methyl guanosine (m7G) linked via an inverted 5'-5' triphosphate bridge to an initiating guanosine ribonucleotide; major species at pH 7.3.


An O-(S-acylpantetheine-4'-phosphoryl)serine(1-) residue in which the S-acyl group is specified as 5-hexenoyl.


Ac-DEVD-CHO

A tetrapeptide consisting of two L-aspartic acid residues, an L-glutamyl residue and an L-valine residue with an acetyl group at the N-terminal and with the C-terminal carboxy group reduced to an aldehyde. It is an inhibitor of caspase-3/7.


(3-carboxylatophenyl)azo group

A phenylazo group in which the phenyl ring is substituted at the meta position with a deprotonated carboxy group.


name: 3-methyldeoxycytidine 5'-monophosphate zwitterion residue

description: A zwitterionic group derived from 3-methyldeoxycytidine 5'-monophosphate; major species at pH 7.3.


An organoboron compound that is diphenylborane in which the borane hydrogen is replaced by a 2-aminoethoxy group.


N-(2,4-dinitrophenyl)aminohexanoic acid

A C-nitro compound comprising hexanoic acid with a (2,4-dinitrophenyl)amino substituent at position C-6.


BENZO[D]THIAZOLE

An organic heterobicyclic compound that is a fusion product between benzene and thiazole. The parent of the class of benzothiazoles.


Benzothiazole substituted with a hydroxy group at the 2-position.


hydroxy ketone ascaroside

Any glycoside resulting from the reaction of the hydroxy group of a hydroxy ketone with alpha-ascarylopyranose or its derivatives.


quercetin 3,4',7-trissulfate

A quercetin trissulfate having the three sulfo groups placed at the 3-, 4'- and 7-positions.


A trisaccharide derivative consisting of a beta-D-glucosyl residue glycosidically linked to a 5-aminopentyl group and which carries at O-3 a beta-D-glucosyl-(1->3)-2,4-di-O-acetyl-6-deoxy-alpha-L-talosyl disaccharide unit.


An oligosaccharide sulfate formed by sulfating methyl 6-O-sulfo-alpha-D-glucopyranosyl-(1->4)-6-O-sulfo-beta-D-glucopyranoside at O-6 of each glucose residue.


name: 2-[(2S,5S,6S)-6-(hydroxymethyl)-5-[(4-methoxyphenyl)sulfonylamino]-2-oxanyl]acetic acid methyl ester


A branched trisaccharide that is alpha-lactose in which the hydroxy group at position 2 of the glucopyranose moiety has been glycosylated by an alpha-L-fucopyranosyl group.


6-O-methyl dGMP(1-) residue

An organic anionic group obtained by deprotonation of the phosphate OH group of 6-O-methyl dGMP residue; major species at pH 7.3.


CoA ester of bkas#12


An alkyl,acyl-sn-glycero-3-phosphoethanolamine zwitterion in which the alkyl or acyl groups at positions 1 and 2 contain a total of 42 carbons and 6 double bonds.


Conjugate base of bhos#16-CoA


A glycoheptaosylceramide having alpha-D-GalNAc-(1->3)-[alpha-L-Fuc-(1->2)]-beta-D-Gal-(1->3)-[alpha-L-Fuc-(1->4)]-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc as the glycoheptaosyl component.


An amino tetrasaccharide consisting of alpha-D-GlcNS-(1->4)-beta-D-GlcA-(1->4)-alpha-D-GlcNS-(1->4)-beta-D-GlcA in which the hydrogen attached to the anomeric oxygen is replaced by a 4-nitrophenyl group.


An S-substituted N-acetyl-L-cysteine arising from formal 1,4-addition of the side-chain sulfur atom to N-ethylmaleimide.


ISOBUTANOL

An alkyl alcohol that is propan-1-ol substituted by a methyl group at position 2.


C-terminal S-cyano-L-cysteinate residue

An alpha-amino-acid residue anion obtained by deprotonation of the carboxy group of C-terminal S-cyano-L-cysteine residue; major species at pH 7.3.


A synthetic pentapeptide comprising N-acetyl-L-valine (Ac-Val), N-cyclohexylglycine (Chg), L-arginine (Arg), (2S)-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid (Tic)and L-phenylalaninamide (Phe-NH2) residues coupled in sequence.


An N-acyl-beta-D-galactosylsphingosine having a sulfo group at the 3-position on the galactose ring and (15Z)-tetracos-15-enoyl as the N-acyl group.


A bioactive sphingoid, sphinganine, in which the terminal hydroxy group has been replaced by a hydrogen.


A member of the class of imidazoles that is 1H-imidazole substituted by a hydroxymethyl group at position 4.


name: 2-[(2S,5R,6S)-6-(hydroxymethyl)-5-(1-oxopropylamino)-2-oxanyl]acetic acid methyl ester


CoA ester of bkas#30


A glycosylgalactose comprising two alpha-D-galactose units joined via a (1->3)-linkage.


A hydroxycoumarin that is 2H-chromen-2-one substituted by a hydroxy group at positions 4 and 7, and a methyl group at position 5.


A disaccharide derivative consisting of a beta-D-glucosyl residue glycosidically linked to a 5-aminopentyl group and which carries at O-3 a beta-L-rhamnosyl residue.


4-methylumbelliferone sulfate

A member of the class of coumarins that is umbelliferone sulfate which carries a methyl group at position 4. It is a metabolite of 4-methylumbelliferone.


name: 3-(3,4,5-trimethoxyphenyl)propanoic acid [2-(3,5-dimethoxyanilino)-2-oxoethyl] ester


hirsutidin

An anthocyanidin cation consisting of benzopyrylium with hydroxy substituents at positions 3 and 5, a methoxy group at position 7 and a 4-hydroxy-3,5-dimethoxyphenyl group at position 2.


A fatty alcohol that is nonanol that has undergone dehydrogenation to introduce a double bond at any position in the aliphatic chain and in which a hydrogen at position 4 has been replaced by a hydroxy group.


A galactohexaose in which the linkages between the six D-galactosyl residues are beta(1->6).


galactohexaose

A hexasaccharide comprised of galactose residues.


A galactohexaose in which the linkages between the six D-galactosyl residues are beta(1->4).


A galactohexaose in which the linkages between the six D-galactosyl residues are beta(1->3).


A ceramide phosphoethanolamine zwitterion obtained by transfer of a proton from the phospho to the amino group of any N-acylicosaphytosphingosine-1-phosphoethanolamine; major species at pH 7.3.


An organic heterotetracyclic compound that is podophyllotoxin in which the methyl ether group at position 4 of the trimethoxyphenyl group has been cleaved to afford the corresponding phenol.


An organic heterotetracyclic compound that is the 9- epimer of 4'-demethylpodophyllotoxin.


picropodophyllin

An organic heterotetracyclic compound that has a furonaphthodioxole skeleton bearing 3,4,5-trimethoxyphenyl and hydroxy substituents.


podophyllotoxin

An organic heterotetracyclic compound that has a furonaphthodioxole skeleton bearing a 3,4,5-trimethoxyphenyl substituent. It is found in the roots and rhizomes of Podophyllum species and is used for the topical treatment of genital warts.


A trisaccharide that is alpha-D-glucopyranosyl-(1->3)-D-galactopyranose in which the hydroxy group at position 4 of the galactopyranose ring has been converted into the corresponding beta-L-fucopyranosyl derivative.


zoledronic acid

An imidazole compound having a 2,2-bis(phosphono)-2-hydroxyethane-1-yl substituent at the 1-position.


organosilver compound

A compound containing at least one carbon-silver bond.


(5'S,6'R)-C-glycyluridine zwitterion

Major microspecies at pH 7.3.


Conjugate base of bhos#9


name: 5-nitro-2-[(phenylmethyl)amino]benzoic acid [2-(cyclohexylamino)-2-oxoethyl] ester


N(alpha)-acetyl-L-argininyl group

An alpha-aminoacyl group formed by loss of OH from the carboxy group of N(alpha)-acetyl-L-arginine.


CoA ester of bhas#18


CETRORELIX ACETATE

The acetic acid salt of cetrorelix. A gonadotrophin-releasing hormone (GnRH) antagonist, it is used for treatment of infertility and of hormone-sensitive cancers of the prostate and breast.


name: 1alpha,25-dihydroxy-19-norvitamin d3 / 1alpha,25-dihydroxy-19-norcholecalciferol


chloroplast chromosome

category: biolink:CellularComponent biolink:AnatomicalEntity biolink:PhysicalEssence biolink:OrganismalEntity biolink:SubjectOfInvestigation biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: A circular DNA molecule containing chloroplast encoded genes.


plastid chromosome

description: A circular DNA molecule containing plastid encoded genes.


A primary allylic alcohol that is 2-hexene in which a hydrogen at position 1 has been replaced by a hydroxy group.


A hex-2-en-1-ol that has (E)-configuration.


name: 3-[(1,1-dioxo-1,2-benzothiazol-3-yl)amino]propanoic acid [2-(cyclooctylamino)-2-oxoethyl] ester


A branched amino octasaccharide that consists of the linear tetrasaccharide beta-D-Xyl-(1->2)-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc in which the Man residue is substituted at positions 3 and 6 by beta-D-GlcNAc-(1->2)-alpha-D-Man groups.


A branched amino octasaccharide that consists of the linear tetrasaccharide beta-D-Xyl-(1->2)-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-GlcNAc in which the Man residue is substituted at positions 3 and 6 by beta-D-GlcNAc-(1->2)-alpha-D-Man groups.


cytoglobosin G

A cytochalasan alkaloid found in Chaetomium globosum.


An amino pentasaccharide consisting of two units of beta-D-galactopyranosyl-(1->4)-N-acetamido-beta-D-glucosamine, attached by (1->3)- and (1->6)-linkages to a D-galactopyranose.


beta-D-Galp-(1->4)-beta-D-GlcpNAc-(1->3)-[beta-D-Galp-(1->4)-beta-D-GlcpNAc-(1->6)]-D-Galp in which the configuration of the D-galactosyl residue at the reducing end is beta.


methylmercury compound

An  alkylmercury compound in which the  alkyl group specified is methyl.


A branched mannopentaose comprised of a linear tetrasaccharide unit of D-mannose residues linked sequentially alpha(1->3), alpha(1->6) and alpha(1->6), to the residue at the reducing end is also linked alpha(1->3) a fifth D-mannose residue.


CISATRACURIUM BESYLATE

The (1R,1'R,2R,2'R)-diastereoisomer of atracurium besylate. Commercial preparations of atracurium are mixtures of 10 stereoisomers, of which cisatracurium generally constitutes about 15%. Cisatracurium besylate is about 3 times more potent than the mixture of atracurium isomers as a neuromuscular blocking agent, and is used as a muscle relaxant for endotracheal intubation, to aid controlled ventilation, and in general anaesthesia.


S-sulfanylglutathione

A Glu-Cys-Gly tripeptide derivative of glutathione distinguished by an additional sulfhydryl substituent on the S of Cys.


A member of the class of quinolones that is the amide obtained from formal condensation of the carboxy group of 1-allyl-4-hydroxy-2-oxo-1,2-dihydroquinoline-3-carboxylic acid with the amino group of 2-amino-1,3-thiazole.


coronate

A chelate complex of crown compound (coronand).


inorganic mercury salt

A mercury salt that lacks C-H bonds


halooxometallate anion

An anionic coordination entity where halido and oxido ligands are coordinated to a metal centre.


fluorooxometallate anion

An anionic coordination entity where fluorido and oxido ligands are coordinated to a metal centre.


iodooxometallate anion

An anionic coordination entity where iodido and oxido ligands are coordinated to a metal centre.


bromooxometallate anion

An anionic coordination entity where bromido and oxido ligands are coordinated to a metal centre.


A trimethoxyflavone that is myricetin in which the hydroxy groups at position 3, 3' and 5' have been replaced by methoxy groups.


viridicatin

A hydroxyquinolone that is 3-hydroxyuinolin-2(1H)-one which is substituted at position 4 by a phenyl groups. Isolated from the mycelium of several Penicillium species, it exhibits strong antibiotic activity against M. tuberculosis and also against B. subtilis, S. aureus and S. cerevisiae.


A branched amino octasaccharide comprising two beta-D-galactosyl-(1->4)-[beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1->6)]-N-acetyl-beta-D-glucosamine tetrasaccharide units connected via a (1->3) linkage.


An oligosaccharide derivative that is an undecasaccharide in which two tetrasaccharide branches, each formed from alpha-L-fucosyl-(1->3)-[beta-D-galactosyl-(1->4)]-N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannose, are linked (1->3) and (1->6) to the mannose residue of a trisaccharide chain consisting of mannose and two N-acetylglucosamine residues all linked beta(1->4) with a beta-configuration of the anomeric carbon of the N-acetylglucosamine residue at the reducing end.


PEDUNCULOSUMOSIDE C

A homoflavonoid glycoside that is 5'-prenylophioglonol attached to 2-O-beta-D-glucopyranosyl-beta-D-glucopyranosyl residue at position 7 via glycosidic linkage. It has been isolated from the whole plant of Ophioglossum pedunculosum and exhibits anti-HBV activity.


O-acyl carbohydrate

A carbohydrate derivative in which the hydrogen atom of at least one alcoholic hydroxy group of a carbohydrate has been replaced by an acyl substituent.


name: (18S )-18-O-b-D-Apiofuranosyl-(1-4)-b-D-glucopyranosideof protoconstipatic acid


O-feruloylgalactaric acid

Galactaric acid in which the hydrogen of one of the alcoholic hydroxy groups has been replaced by a feruloyl group.


name: (18S )-18-O-a-L-rhamnopyranosyl-(1-4)-b-D-glucopyranosideto protoconstipatic acid


The O-acyl carbohydrate that is D-galactopyranose trans-feruloylated at position 6.


alpha,alpha'-trehalose 6,6'-bismycolate

A trehalose mycolate compound consisting of two mycolate groups attached to the 6- and 6'-positions of alpha,alpha'-trehalose.


2-O-sinapoyl-D-glucaric acid

The 2-O-sinapoyl derivative of D-glucaric acid.


salicyluric beta-D-glucuronide

A carboxylic ester resulting from the formal condensation of the carboxy group of salicyluric acid with the anomeric hydroxy group of beta-D-glucuronic acid.


An aminodisaccharide that is 2-acetamido-2-deoxy-D-galactitol in which the hydroxy group at position 3 has been converted into the 6-O-sulfo-beta-D-galactopyranose derivative.


name: (18R )-18-O-a-L-Rhamnopyranosyl-(1-6)-b-D-glucopyranosideof murolic acid


A steroid glucosiduronic acid obtained by formal condensation of the carboxy group of hyodeoxycholic acid with the anomeric hydroxy group of beta-D-glucuronic acid.


An O-acyl carbohydrate that is beta-D-glucose carrying sinapoyl groups at the 1- and 2-positions.


A steroid glucosiduronic acid obtained by formal condensation of the carboxy group of hyocholic acid with the anomeric hydroxy group of beta-D-glucuronic acid.


A glycosyl alditol consisting of alpha-D-glucopyranose and D-glucitol residues joined in sequence by a (1->6)-glycosidic bond.


An O-acyl carbohydrate consisting of beta-D-glucose carrying a O-trans-cinnamoyl group at the anomeric position.


A steroid glucosiduronic acid obtained by formal condensation of the carboxy group of lithodeoxycholic acid with the anomeric hydroxy group of beta-D-glucuronic acid.


A steroid glucosiduronic acid obtained by formal condensation of the carboxy group of chenodeoxycholic acid with the anomeric hydroxy group of beta-D-glucuronic acid.


An O-acyl carbohydrate that is beta-D-glucose bearing a vanilloyl substituent at position 1.


name: (18R )-18-O-b-D-Glucopyranoside of murolic acid


name: (18R)-O-B-D-glucopyranosyl-(1-3)-B-D-glucopyranoside of murolic acid


An O-acyl carbohydrate consisting of maltose carrying an anomeric O-acetyl substituent.


2-(E)-O-feruloyl-D-galactaric acid

O-Feruloylgalactaric acid in which the hydroxy proton replaced by the feruloyl group is the one at C-2 when the galactaric acid molecule is oriented in the D-configuration.


A glycosyl alditol derivative that is 2-acetamido-2-deoxy-D-galactitol in which the hydroxy group at position 3 has been glycosylated by an alpha-L-fucopyranosyl-(1->2) beta-D-galactopyranosyl group.


cholic acid 24-O-(beta-D-glucuronide)

A steroid glucosiduronic acid obtained by formal condensation of the carboxy group of cholic acid with the anomeric hydroxy group of beta-D-glucuronic acid.


A steroid glucosiduronic acid obtained by formal condensation of the carboxy group of deoxycholic acid with the anomeric hydroxy group of beta-D-glucuronic acid.


name: (18S )-18-O-a-D-Arabinofuranosyl-(1-6)-b-D-glucopyranosideof protoconstipatic acid


penta-O-acetyl-alpha-D-galactose

An O-acyl carbohydrate that consists of alpha-D-galactopyranose bearing five O-acetyl substituents.


An O-acyl carbohydrate obtained by formal condensation of the carboxy group of 2-oxindole-3-acetic acid with the anomeric hydroxy group of beta-D-glucose.


trehalose monomycolate

Any trehalose bearing a single O-mycolate substituent; obtained via extraction of the cell wall of Mycobacterium bovis.


An O-acyl carbohydrate obtained by formal condensation of the carboxy group of gallic acid with the 2-hydroxy group of D-glucose.


alpha,alpha'-trehalose 6-mycolate

A trehalose monomycolate comprising alpha,alpha'-trehalose having the mycolate group attached to the 6-position.


O-(arachidonyl)-beta-D-glucuronate

Major species at pH 7.3


phaseollidin hydrate

A member of the class of pterocarpans that is phaseollidin in which the prenyl group is replaced by a 3-hydroxy-3-methylbutyl group.


A trisaccharide consisting of L-fucose linked alpha(1->2') to a beta-lactose unit.


(2R,3S,11R)-aszonalenin zwitterion

Major microspecies at pH 7.3.


imidazopyridazine

An organic heterobicyclic compound that consists of an imidazole ring ortho-fused to a pyridazine ring.


fluoxetine hydrochloride

A racemate comprising equimolar amounts of (R)- and (S)-fluoxetine hydrochloride. A selective serotonin reuptake inhibitor (SSRI), it is used for the treatment of depression (and the depressive phase of bipolar disorder), bullimia nervosa, and obsessive-compulsive disorder.


Descovy

A mixture composed of emtricitabine and tenofovir alafenamide fumarate (trade name Descovy) that is used in combination with other antiretroviral agents, for the treatment of HIV-1 infection in adults and pediatric patients 12 years of age and older.


A galactotriose consisting of two alpha-D-galactopyranosyl groups and a D-galactofuranose group linked in sequence by (1->4) and (1->3) glycosidic bonds.


galactotriose

Any trisaccharide composed of 3 galactose moieties.


A galactotriose consisting of alpha-D-galactopyranose, beta-D-galactopyranose and D-galactpyranose joined in sequence by (1->4) glycosidic bonds.


A galactotriose consisting of beta-D-galactopyranose, alpha-D-galactopyranose and D-galactopyranose joined in sequence by (1->3) and (1->4) glycosidic linkages.


A galactotriose consisting of two alpha-D-galactopyrase residues and a D-galactopyranose residue joined in sequence by (1->3) and (1->4) glycosidic bonds.


A galactotriose consisting of two beta-D-galatopyranose residues and a D-galactopyranose residue joined in sequence by (1->6) and (1->4) glycosidic bonds.


A galactotriose consisting of two beta-D-galactofuranose residues and a D-galactofuranose residue joined in sequence by (1->5) glycosidic bonds.


A galactotriose consisting of two alpha-D-galactopyranose units and a beta-D-galactopyranose joined in sequence by (1->4) glycosidic linkages.


A galactotriose consisting of two beta-D-galactopyranose residues and a D-galactopyranose residue joined in sequence by (1->4) glycosidic bonds.


A branched trisaccharide comprising beta-D-galactose (at the reducing end), to which are linked (1->2) and (1->6) alpha-D-galactosyl residues.


A galactotriose composed of three beta-D-galactopyranose units joined by (1->3)-linkages.


A galactotriose that is beta-D-galatopyranose in which the hydroxy groups at positions 3 and 6 have been glycosylated by alpha-D-galactopyranosyl residues.


A galactotriose composed of three beta-D-galactopyranose units joined by (1->2)-linkages.


A galactotriose consisting of two alpha-D-galactopyranose residues and a beta-D-galactopyranose residue joined in sequence by (1->6) and (1->3) glycosidic bonds.


A galactotriose consisting of two alpha-D-galactopyranose residues and a beta-D-galactopyraonse residue joined in sequence by (1->6) glycosidic bonds.


A galactotriose composed of three beta-D-galactose units joined by (1->6)-linkages.


A galactotriose consisting of two alpha-D-galactopyranose residues and a galactopyranose residue joined in sequence by (1->2) glycosidic linkages.


A galactotriose consisting of D-galactopyranose, alpha-D-galactopyranose and beta-D-galactopyranose residues joined in sequence by (1->4) glycosidic bonds.


A galactotriose composed of three beta-D-galactopyranose units joined by (1->4)-linkages.


A galactotriose that is beta-D-galactopyranose in which the hydroxy groups at positions 2 and 6 have been converted to the corresponding beta-D-galactopyranosyl derivatives.


A galactotriose consisting of three beta-D-galactofuranose residues joined in sequence by (1->6) and (1->5) glycosidic bonds.


A galactotriose in which the three D-galactosyl residues are connected via sequential alpha-(1->3)- and beta-(1->4)-linkages.


A galactotriose that is D-galactpyranose in which the hydroxy groups at positions 2 and 3 have each been converted into the corresponding beta-D-galactopyranosyl derivative.


A galactotriose that is beta-D-galactofuranose in which the hydroxy groups at positions 3 and 6 have been glycosylated by beta-D-galatopyranosyl residues.


A galactotriose consisting of three alpha-D-galactopyranose residues joined in sequence by (1->6) and (1->3) glycosidic bonds.


A beta-D-Galp-(1->3)-alpha-D-Galp-(1->4)-D-Galp in which the anomeric hydroxy group has beta configuration


name: thiocyanic acid [4-[(2-chloro-1-oxoethyl)amino]-3,5-dimethylphenyl] ester


fragin

A natural product found in Burkholderia cenocepacia, which zwitterion is an iron chelator with antifungal properties.


O-guanylyl-L-tyrosine(1-) residue

An anionic amino-acid residue  obtained by removal of a proton form the phosphate group of O-guanylyl-L-tyrosine residue; major species at pH 7.3.


Conjugate base of bhas#9


dihydrostreptomycin 6-phosphate(1+)

Conjugate acid of dihydrostreptomycin 6-phosphate arising from deprotonation of the phosphate OH groups and protonation of the secondary amino and both guanidino groups; major species at pH 7.3.


N-hexacosenoyl-D-galactosylsphingosine

An N-acyl-D-galactosylsphingosine in which the ceramide N-acyl group is  composed of 26 carbons and 1 double bond.


A dihydroceramide in which the ceramide N-acyl group is specified as 2-hydroxyeicosanoyl.


acetohydrazide

A carbohydrazide that is hydrazine in which one of the hydrogens is replaced by an acetyl group.


carbohydrazonic acid

A carbohydrazonic acid is an acid in which the carbonyl oxygen atom of the carboxylic acid group has been replaced by =NNH2.


A tetrahydroxyflavone that is kaempferol substituted by a lavandulyl group at position 8. Isolated from Sophora flavescens, it exhibits antioxidant activity.


(S)-fluoxetine

An N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine that has S configuration. [The antidepressant drug fluoxetine is a racemate comprising equimolar amounts of (R)- and (S)-fluoxetine].