name: NACHT, LRR and PYD domains-containing protein 12 deaminated 1 (human)

description: A NACHT, LRR and PYD domains-containing protein 12 (human) that has been deaminated on the residue at the position equivalent to Asn-780 of the amino acid sequence represented by UniProtKB:P59046-1. Example: UniProtKB:P59046-1, Asn-780, MOD:00684.


An amino nonasaccharide derivative that is beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-GlcNAc in which the mannosyl group is substituted at position 3 by a beta-D-GlcNAc-(1->2)-alpha-D-Man group and at position 6 by an alpha-Neu5Ac-(2->6)-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->2)-alpha-D-Man group.


name: YD157_YEAST Uncharacterized protein YDL157C, mitochondrial (sprot)

description: A protein that is a translation product of the YDL157C gene in yeast.


name: histone deacetylase 4 isoform m2 (mouse)

description: A histone deacetylase 4 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q6NZM9-2.


uncharacterized lipoprotein YajG

A protein that is a translation product of the Escherichia coli K-12 yajG gene or a 1:1 ortholog thereof.


name: YAJG_ECOLI Uncharacterized lipoprotein YajG (sprot)

description: An uncharacterized lipoprotein YajG that is encoded in the genome of Escherichia coli K-12.


name: RAF proto-oncogene serine/threonine-protein kinase isoform 1

description: A RAF proto-oncogene serine/threonine-protein kinase that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P04049-1 or a 1:1 ortholog thereof.


name: RAF proto-oncogene serine/threonine-protein kinase isoform 1 phosphorylated 3 (human)

description: A RAF proto-oncogene serine/threonine-protein kinase isoform 1 phosphorylated 3 in human. UniProtKB:P04049-1, Ser-259/Ser-621, MOD:00046.


name: RAF proto-oncogene serine/threonine-protein kinase isoform 1 (human)

description: A RAF proto-oncogene serine/threonine-protein kinase isoform 1 that is encoded in the genome of human.


name: RAF proto-oncogene serine/threonine-protein kinase isoform 1 phosphorylated 1

description: A RAF proto-oncogene serine/threonine-protein kinase isoform 1 phosphorylated form in which the phosphorylation occurs at two consecutive Tyr residues by active Src kinases. Example: UniProtKB:P04049-1, Tyr-340/Tyr-341, MOD:00048.


name: RAF proto-oncogene serine/threonine-protein kinase isoform 1 phosphorylated 2

description: A RAF proto-oncogene serine/threonine-protein kinase isoform 1 phosphorylated form in which the phosphorylation occurs at two consecutive Ser residues by PAK1. Example: UniProtKB:P04049-1, Ser-338/Ser-339, MOD:00046.


name: RAF proto-oncogene serine/threonine-protein kinase isoform 1 (mouse)

description: A RAF proto-oncogene serine/threonine-protein kinase isoform 1 that is encoded in the genome of mouse.


name: RAF proto-oncogene serine/threonine-protein kinase isoform 1 phosphorylated 2 (human)

description: A RAF proto-oncogene serine/threonine-protein kinase isoform 1 phosphorylated 2 in human. UniProtKB:P04049-1, Ser-338/Ser-339, MOD:00046.


name: RAF proto-oncogene serine/threonine-protein kinase isoform 1 phosphorylated 3

description: A RAF proto-oncogene serine/threonine-protein kinase isoform 1 that has been phosphorylated on the two 14-3-3 binding sites. Example: UniProtKB:P04049-1, Ser-259/Ser-621, MOD:00046.


name: RAF proto-oncogene serine/threonine-protein kinase isoform 1 phosphorylated form

description: A RAF proto-oncogene serine/threonine-protein kinase isoform 1 that includes at least one phosphorylated residue.


name: RAS guanyl-releasing protein 1 isoform h2 (human)

description: A RAS guanyl-releasing protein 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O95267-2.


name: long-wave-sensitive opsin 1 sequence variant P307L (human)

description: A long-wave-sensitive opsin 1 (human) that has a Leu residue at the position equivalent to Pro-307 of the amino acid sequence represented by UniProtKB:P04000. UniProtKB:P04000, Pro-307, CHEBI:30006.


name: long-wave-sensitive opsin 1 sequence variant C203R (human)

description: A long-wave-sensitive opsin 1 (human) that has an Arg residue at the position equivalent to Cys-203 of the amino acid sequence represented by UniProtKB:P04000. UniProtKB:P04000, Cys-203, CHEBI:29952.


name: long-wave-sensitive opsin 1 sequence variant G338E (human)

description: A long-wave-sensitive opsin 1 (human) that has a Glu residue at the position equivalent to Gly-338 of the amino acid sequence represented by UniProtKB:P04000. UniProtKB:P04000, Gly-338, CHEBI:29972.


name: histone H3.1, initiator methionine removed symmetrically-dimethylated 1 (human)

description: A histone H3.1 (human) that has had the initiator methionine removed and that has been symmetrically-dimethylated on the residue at the position equivalent to Arg-9 of the amino acid sequence represented by UniProtKB:P68431. UniProtKB:P68431, 2-136, Arg-9, MOD:00076.


name: tissue factor pathway inhibitor isoform Beta (human)

description: A tissue factor pathway inhibitor (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P10646-2.


DTPD_ECOLI Dipeptide permease D (sprot)

A dipeptide permease D that is encoded in the genome of Escherichia coli K-12.


dipeptide permease D

A protein that is a translation product of the Escherichia coli K-12 dtpD gene or a 1:1 ortholog thereof.


name: PTR45_ARATH Protein NRT1/ PTR FAMILY 5.7 (sprot)

description: A dipeptide permease D that is encoded in the genome of Arabidopsis thaliana.


aldehydo-L-mannose

The L-enantiomer of aldehydo-mannose.


name: serine/Arginine-related protein 53 isoform h2 (human)

description: A serine/Arginine-related protein 53 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q96IZ7-2.


name: cyclin-dependent kinase inhibitor 2A, isoforms h1/h2/h3/h5 sequence variant P81R (human)

description: A cyclin-dependent kinase inhibitor 2A, isoforms h1/h2/h3/h5 (human) that has an Arg residue at the position equivalent to Pro-81 of the amino acid sequence represented by UniProtKB:P42771-1. Example: UniProtKB:P42771-1, Pro-81, CHEBI:29952.


name: FAMA_ARATH Transcription factor FAMA (sprot)

description: A protein that is a translation product of the FAMA gene in Arabidopsis thaliana.


name: DNA repair protein complementing XP-C cells isoform h2 (human)

description: A DNA repair protein complementing XP-C cells (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q01831-2.


protein FlxA

A protein that is a translation product of the Escherichia coli K-12 flxA gene or a 1:1 ortholog thereof.


FLXA_ECOLI Protein FlxA (sprot)

A protein FlxA that is encoded in the genome of Escherichia coli K-12.


Hernández-Aguirre Negrete syndrome

category: biolink:Disease biolink:DiseaseOrPhenotypicFeature biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing

description: A syndrome is characterized by major seizures, dysmorphic features (round face, bulbous nose, wide mouth, prominent philtrum), pes planus, psychomotor retardation and obesity. It has been described in five children (three boys and two girls, one of whom died in infancy) from two unrelated Mexican families. This condition is likely to be transmitted as an autosomal recessive trait.


name: F-box/WD repeat-containing protein 1A methylated 1 (human)

description: An F-box/WD repeat-containing protein 1A (human) that has been methylated on the residue at the position equivalent to Cys-137 of the amino acid sequence represented by UniProtKB:Q9Y297-1. Example: UniProtKB:Q9Y297-1, Cys-137, MOD:00660.


name: versican core protein O-glycosylated 117 (human)

description: A versican core protein (human) that has been O-glycosylated at the residue equivalent to Thr-1569 of the amino acid sequence represented by UniProtKB:P13611-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P13611-1, Thr-1569, MOD:00005~GNO:G43417UB.


N-undecanoylglycine

An N-acylglycine with an acyl group that is undecanoyl.


name: RN19B_HUMAN E3 ubiquitin-protein ligase RNF19B (sprot)

description: An E3 ubiquitin-protein ligase RNF19B that is encoded in the genome of human.


name: E3 ubiquitin-protein ligase RNF19B isoform h4 (human)

description: An E3 ubiquitin-protein ligase RNF19B (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q6ZMZ0-4.


name: E3 ubiquitin-protein ligase RNF19B deaminated 1 (human)

description: An E3 ubiquitin-protein ligase RNF19B (human) that has been deaminated on the residue at the position equivalent to Gln-720 of the amino acid sequence represented by UniProtKB:Q6ZMZ0-1. Example: UniProtKB:Q6ZMZ0-1, Gln-720, MOD:00685.


name: E3 ubiquitin-protein ligase RNF19B isoform h1 (human)

description: An E3 ubiquitin-protein ligase RNF19B (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q6ZMZ0-1.


name: E3 ubiquitin-protein ligase RNF19B methylated 1 (human)

description: An E3 ubiquitin-protein ligase RNF19B (human) that has been methylated on the residue at the position equivalent to Cys-203 of the amino acid sequence represented by UniProtKB:Q6ZMZ0-1. Example: UniProtKB:Q6ZMZ0-1, Cys-203, MOD:00660.


name: E3 ubiquitin-protein ligase RNF19B isoform h3 (human)

description: An E3 ubiquitin-protein ligase RNF19B (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q6ZMZ0-3.


name: E3 ubiquitin-protein ligase RNF19B cysteinylated 1 (human)

description: An E3 ubiquitin-protein ligase RNF19B (human) that has been cysteinylated on the residue at the position equivalent to Cys-203 of the amino acid sequence represented by UniProtKB:Q6ZMZ0-1. Example: UniProtKB:Q6ZMZ0-1, Cys-203, MOD:00765.


name: E3 ubiquitin-protein ligase RNF19B cysteinylated 2 (human)

description: An E3 ubiquitin-protein ligase RNF19B (human) that has been cysteinylated on the residue at the position equivalent to Cys-695 of the amino acid sequence represented by UniProtKB:Q6ZMZ0-1. Example: UniProtKB:Q6ZMZ0-1, Cys-695, MOD:00765.


name: E3 ubiquitin-protein ligase RNF19B phosphorylated 1 (human)

description: An E3 ubiquitin-protein ligase RNF19B (human) that has been phosphorylated on the residue at the position equivalent to Ser-270 of the amino acid sequence represented by UniProtKB:Q6ZMZ0-1. Example: UniProtKB:Q6ZMZ0-1, Ser-270, MOD:00046.


name: E3 ubiquitin-protein ligase RNF19B isoform h2 (human)

description: An E3 ubiquitin-protein ligase RNF19B (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q6ZMZ0-2.


Pathology Result

category: biolink:PhenotypicFeature biolink:DiseaseOrPhenotypicFeature biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing

description: The outcome of a pathologic examination.


Large Cell Dysplasia

description: A premalignant neoplastic lesion of the liver.  It is characterized by the presence of hepatocytes with enlarged nuclei and cytoplasm, nuclear pleomorphism, multinucleation, and hyperchromasia.


name: progressive transformation of germinal centers

description: Progressive transformation of germinal centers is a condition in which a lymph node becomes very enlarged (lymphadenopathy). Typically, only one lymph node is affected, though PTGC can involve multiple lymph nodes. Theneck is the most common location of affected lymph nodes, but PTGC may also affect lymph nodes in the groin and armpits. adults are more frequently affected than children, but children have a higher chance of developing PTGC multiple times (recurrence). PTGC is not considered a precancerous condition, though it has been associated with Hodgkin lymphoma.


cervical metaplasia

description: Metaplastic changes in the cervical glandular or squamous epithelium.


Histopathology Result

description: A finding resulting from the examination of a tissue sample under light or electron microscopy.


angiomatosis

description: A benign diffuse vascular proliferation usually occurring in young adults. It is characterized by the formation of capillary-sized and cavernous vascular spaces. Patients present with diffuse persistent swelling.


nephrogenic adenoma

description: So-called nephrogenic adenoma is a distinct metaplastic lesion of the urothelium characterized by aggregates of cuboidal or hobnail cells. These cells line thin papillary fronds on the surface or form tubular structures within the lamina propria.


Small Cell Dysplasia

description: A premalignant neoplastic lesion of the liver.  It is characterized by the presence of hepatocytes with decreased cell volume, increased nuclear/cytoplasmic ratio, basophilia, mild nuclear pleomorphism, and hyperchromasia.


name: Massive Sinusoidal Histiocytic Infiltrate


Sinus Histiocytosis

description: A morphologic finding indicating the presence of histiocytic infiltrates within distended lymph node sinuses.


Morphologic Finding

description: A light microscopic finding that describes the cellular characteristics and architectural patterns of cell populations in a tissue sample.


name: proteinase-activated receptor 1 deaminated 1 (human)

description: A proteinase-activated receptor 1 (human) that has been deaminated on the residue at the position equivalent to Asn-75 of the amino acid sequence represented by UniProtKB:P25116. UniProtKB:P25116, Asn-75, MOD:00684.


name: proteinase-activated receptor 1, signal peptide removed form (human)

description: A proteinase-activated receptor 1 (human) that has had the signal peptide removed. UniProtKB:P25116, 22-425.


name: Refractory Malignant Gastrointestinal Stromal Tumor

description: Malignant gastrointestinal stromal tumor that is resistant to treatment.


Refractory Soft Tissue Sarcoma

description: A soft tissue sarcoma that does not respond to treatment.


Refractory Epithelioid Sarcoma

description: An epithelioid sarcoma that does not respond to treatment.


Refractory Synovial Sarcoma

description: Synovial sarcoma that does not respond to treatment.


name: Refractory Extraskeletal Myxoid Chondrosarcoma

description: Extraskeletal myxoid chondrosarcoma that does not respond to treatment.


name: Refractory Undifferentiated Pleomorphic Sarcoma

description: Undifferentiated pleomorphic sarcoma that does not respond to treatment.


Refractory Alveolar Rhabdomyosarcoma

description: Alveolar rhabdomyosarcoma that does not respond to treatment.


Refractory Kaposi Sarcoma

description: Kaposi sarcoma that is resistant to treatment.


Refractory Alveolar Soft Part Sarcoma

description: Alveolar soft part sarcoma that is resistant to treatment.


name: Refractory Childhood Soft Tissue Sarcoma

description: Childhood soft tissue sarcoma that is resistant to treatment.


name: Refractory Desmoplastic Small Round Cell Tumor

description: Desmoplastic small round cell tumor that is resistant to treatment.


Refractory Childhood Rhabdomyosarcoma

description: Childhood rhabdomyosarcoma that is resistant to treatment.


Refractory Rhabdomyosarcoma

description: Rhabdomyosarcoma that does not respond to treatment.


name: cytoplasmic dynein 1 light intermediate chain 2 phosphorylated 1

description: A cytoplasmic dynein 1 light intermediate chain 2 that has been phosphorylated on the residue at the position equivalent to Ser-194 of the amino acid sequence represented by UniProtKB:Q6PDL0. Example: UniProtKB:Q6PDL0, Ser-194, MOD:00046.


name: cytoplasmic dynein 1 light intermediate chain 2 phosphorylated 1 (mouse)

description: A cytoplasmic dynein 1 light intermediate chain 2 phosphorylated 1 in mouse. UniProtKB:Q6PDL0, Ser-194, MOD:00046.


SODIUM PHENYLBUTYRATE

The organic sodium salt of 4-phenylbutyric acid. A prodrug for phenylacetate, it is used to treat urea cycle disorders.


name: NUAK family SNF1-like kinase 2 isoform m1 (mouse)

description: A NUAK family SNF1-like kinase 2 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8BZN4-1.


name: NUAK2_MOUSE NUAK family SNF1-like kinase 2 (sprot)

description: A NUAK family SNF1-like kinase 2 that is encoded in the genome of mouse.


name: NUAK family SNF1-like kinase 2 isoform m2 (mouse)

description: A NUAK family SNF1-like kinase 2 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8BZN4-2.


name: PMT1_YEAST Dolichyl-phosphate-mannose--protein mannosyltransferase 1 (sprot)

description: A protein that is a translation product of the PMT1 gene in yeast.


2'-deoxyguanosine 3'-monophosphate

A deoxyguanosine phosphate having a monophosphate group located at the 3'-position.


2'-deoxyadenosine 3'-monophosphate

A 2'-deoxyadenosine phosphate having a monophosphate group located at the 3'-position.


A pyrimidine 2'-deoxyribonucleoside 3'-monophosphate that is the mono-(5-bromo-4-chloro-indol-3-yl) ester of thymidine 3'-phosphate.


2'-deoxyuridine 3'-monophosphate

A pyrimidine 2'-deoxyribonucleoside 3'-monophosphate having uracil as the nucleobase.


thymidine 3'-monophosphate

A pyrimidine 2'-deoxyribonucleoside 3'-monophosphate having thymine as the nucleobase.


name: Ral GTPase-activating protein subunit alpha-1 isoform m1 (mouse)

description: A Ral GTPase-activating protein subunit alpha-1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q6GYP7-1.


name: NEP_I78A1 Nuclear export protein (sprot)

description: An influenzavirus nuclear export protein that is encoded in the genome of the H8N4 strain A/Mallard/Alberta/827/1978.


name: S19A1_RAT Reduced folate transporter (sprot)

description: A reduced folate transporter that is encoded in the genome of rat.


epiphyseal dysplasia, multiple, 3

description: Any multiple epiphyseal dysplasia in which the cause of the disease is a mutation in the COL9A3 gene.


name: negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway

category: biolink:BiologicalProcess biolink:Occurrent biolink:OntologyClass biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing 2 (NOD2) pathway.


name: negative regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of a nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway (NLR) pathway.


name: negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing 1 (NOD1) pathway.


name: squamosa promoter-binding-like protein 16 isoform 2 (Arabidopsis thaliana)

description: A squamosa promoter-binding-like protein 16 (Arabidopsis thaliana) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q700C2-2.


orbit embryonal rhabdomyosarcoma

description: A malignant mesenchymal neoplasm that arises from the orbit. It is characterized by the presence of skeletal muscle tissue exhibiting embryonic features.


Metastatic embryonal rhabdomyosarcoma

description: Embryonal rhabdomyosarcoma that has spread from its original site of growth to another anatomic site.


Middle Ear Embryonal Rhabdomyosarcoma

description: A rare embryonal rhabdomyosarcoma that arises in the middle ear.


name: adult vagina botryoid embryonal rhabdomyosarcoma

description: A morphologic variant of embryonal rhabdomyosarcoma arising from the vagina. It is characterized by the formation of a cambium layer in the affected tissue and polypoid nodules with an abundant myxoid stroma. It occurs in female adults.


botryoid rhabdomyosarcoma

description: A morphologic variant of embryonal rhabdomyosarcoma arising from organs with a mucosal epithelial surface. It is characterized by the formation of a cambium layer in the affected tissue and polypoid nodules within an abundant myxoid stroma.


adult botryoid rhabdomyosarcoma

description: A morphologic variant of embryonal rhabdomyosarcoma occurring in adults. The neoplasm arises from organs containing a mucosal epithelial surface. It is characterized by the formation of a cambium layer in the affected tissue and polypoid nodules with an abundant myxoid stroma.


name: childhood vagina botryoid rhabdomyosarcoma

description: A morphologic variant of embryonal rhabdomyosarcoma occurring in female children. The neoplasm arises from the vagina. It is characterized by the formation of a cambium layer in the affected tissue and polypoid nodules with an abundant myxoid stroma.


embryonal rhabdomyosarcoma of bladder

description: An embryonal rhabdomyosarcoma arising from the bladder. It is the most common type of rhabdomyosarcoma of the bladder affecting young children.


prostate embryonal rhabdomyosarcoma

description: A malignant mesenchymal neoplasm of the prostate. It is characterized by the presence of skeletal muscle exhibiting embryonic features.


Anaplastic embryonal rhabdomyosarcoma

description: A morphologic variant of embryonal rhabdomyosarcoma.  It is characterized by the presence of large hyperchromatic and anaplastic cells.


name: vulvar childhood botryoid-type embryonal rhabdomyosarcoma

description: A morphologic variant of embryonal rhabdomyosarcoma occurring in female children. The neoplasm arises from the vulva. It is characterized by the formation of a cambium layer in the affected tissue and polypoid nodules with an abundant myxoid stroma.


childhood botryoid rhabdomyosarcoma

description: A morphologic variant of embryonal rhabdomyosarcoma occurring in children. The tumor arises from organs with a mucosal epithelial surface. It is characterized by the formation of a cambium layer in the affected tissue and polypoid nodules within an abundant myxoid stroma.


name: botryoid-type embryonal rhabdomyosarcoma of the vagina

description: A morphologic variant of embryonal rhabdomyosarcoma arising from the vagina. It is characterized by the formation of a cambium layer in the affected tissue and polypoid nodules within an abundant myxoid stroma.


Childhood Embryonal Rhabdomyosarcoma

description: A poorly circumscribed morphologic variant of rhabdomyosarcoma occurring in children.  The neoplasm is characterized by the presence of primitive skeletal muscle in any stage of myogenesis.


name: LOX1_SOYBN Seed linoleate 13S-lipoxygenase-1 (sprot)

description: A protein that is a translation product of the LOX1.1 gene in Glycine max.


name: dual specificity protein phosphatase 18 isoform 1 (mouse)

description: A dual specificity protein phosphatase 18 isoform 1 that is encoded in the genome of mouse.


AMO_ECOLI Primary amine oxidase (sprot)

A primary amine oxidase that is encoded in the genome of Escherichia coli K-12.


primary amine oxidase

A protein that is a translation product of the Escherichia coli K-12 tynA gene or a 1:1 ortholog thereof.


name: primary amine oxidase, signal peptide removed form

description: A primary amine oxidase that has had the signal peptide removed.


sororin phosphorylated 1 (human)

A sororin (human) that has been post-translationally modified to include phosphoserine at positions 21 and 75, and phosphothreonine at position 159 of the amino acid sequence represented by UniProtKB:Q96FF9. UniProtKB:Q96FF9, Ser-21/Ser-75, MOD:00046|Thr-159, MOD:00047.


name: ZN106_MOUSE Zinc finger protein 106 (sprot)

description: A zinc finger protein 106 that is encoded in the genome of mouse.


name: zinc finger protein 106 isoform m2 (mouse)

description: A zinc finger protein 106 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O88466-2.


name: zinc finger protein 106 isoform m1 (mouse)

description: A zinc finger protein 106 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O88466-1.


name: zinc finger protein 106 isoform m3 (mouse)

description: A zinc finger protein 106 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O88466-3.


name: LIM domain-containing protein 2 cysteinylated 2 (human)

description: A LIM domain-containing protein 2 (human) that has been cysteinylated on the residue at the position equivalent to Cys-88 of the amino acid sequence represented by UniProtKB:Q9BT23. UniProtKB:Q9BT23, Cys-88, MOD:00765.


plexin-C1 N-glycosylated 7 (human)

A plexin-C1 (human) that has been N-glycosylated at the residue equivalent to Asn-871 of the amino acid sequence represented by UniProtKB:O60486-1, in which the glycan composition is represented by GlyTouCan:G98208DX. Example: UniProtKB:O60486-1, Asn-871, MOD:00160~GNO:G98208DX.


name: 4-[3-[[(2,5-dichloroanilino)-methyliminomethyl]thio]-2,5-dioxo-1-pyrrolidinyl]benzoic acid methyl ester


name: ATP-binding cassette sub-family D member 1 sequence variant R617C (human)

description: An ATP-binding cassette sub-family D member 1 (human) that has a Cys residue at the position equivalent to Arg-617 of the amino acid sequence represented by UniProtKB:P33897. UniProtKB:P33897, Arg-617, CHEBI:29950.


neuron-neuron synaptic transmission

description: The process of synaptic transmission from a neuron to another neuron across a synapse.


name: E3 ubiquitin-protein ligase RNF34 isoform h1 (human)

description: An E3 ubiquitin-protein ligase RNF34 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q969K3-1.


name: C1TM_YEAST C-1-tetrahydrofolate synthase, mitochondrial (sprot)

description: A protein that is a translation product of the MIS1 gene in yeast.


name: proline-rich protein 29 isoform h1 (human)

description: A proline-rich protein 29 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P0C7W0-1.


name: Stage 0 Lip Basal Cell Carcinoma AJCC v6 and v7


name: LARP1_MOUSE La-related protein 1 (sprot)

description: A La-related protein 1 that is encoded in the genome of mouse.


La-related protein 1

A protein that is a translation product of the human LARP1 gene or a 1:1 ortholog thereof.


name: La-related protein 1, initiator methionine removed form

description: A La-related protein 1 that has had the initiator methionine removed.


La-related protein 1 isoform m1 (mouse)

A La-related protein 1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q6ZQ58-1.


La-related protein 1 isoform m2 (mouse)

A La-related protein 1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q6ZQ58-2.


La-related protein 1 isoform h1 (human)

A La-related protein 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q6PKG0-1.


name: La-related protein 1, initiator methionine removed form (human)

description: A La-related protein 1 (human) that has had the initiator methionine removed. Example: UniProtKB:Q6PKG0-1, 2-1096.


La-related protein 1 isoform h2 (human)

A La-related protein 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q6PKG0-3.


name: La-related protein 1 phosphorylated 1 (human)

description: A La-related protein 1 (human) that has been phosphorylated on the residue at the position equivalent to Thr-526 of the amino acid sequence represented by UniProtKB:Q6PKG0-1. Example: UniProtKB:Q6PKG0-1, Thr-526, MOD:00047.


name: La-related protein 1 cysteinylated 1 (mouse)

description: A La-related protein 1 (mouse) that has been cysteinylated on the residue at the position equivalent to Cys-841 of the amino acid sequence represented by UniProtKB:Q6ZQ58-1. Example: UniProtKB:Q6ZQ58-1, Cys-841, MOD:00765.


Atypical cartilaginous tumor

description: A locally aggressive, low grade chondrosarcoma arising in the medulla of bone or within the cartilaginous cap of a pre-existing osteochondroma in the appendicular skeleton.


Central Atypical Cartilaginous Tumor

description: A locally aggressive, low-grade chondrosarcoma arising in the medulla of bone in the appendicular skeleton.


name: Secondary Peripheral Atypical Cartilaginous Tumor

description: A locally aggressive, low-grade chondrosarcoma arising within the cartilaginous cap of a pre-existing osteochondroma in the appendicular skeleton.


N-acetyl-S-glyceroyl-L-cysteine

An S-substituted N-acetyl-L-cysteine that is the thioester obtained by formal condensation of the carboxy group of glyceric acid with the thiol group of N-acetyl-L-cysteine.


solasodine

An oxaspiro compound and steroid alkaloid sapogenin with formula C27H43NO2 found in the Solanum (nightshade) family. It is used as a precursor in the synthesis of complex steroidal compounds such as contraceptive pills.


cortistatin A

A member of the class of cortistatins that is substituted by hydroxy groups at positions 1 and 2, a dimethylamino group at the 3alpha position and an isoquinolin-7-yl group at the 17 position, with double bonds at the 9-11 and 10-19 positions (the 1R,2R,17beta enantiomer).


sarcorine

A steroid alkaloid that is 5alpha-pregnane substituted by an acetylamino group at position 3beta, a methyl group at position 20S, and a dimethylamino group at position 21.


HOOKERIANAMIDE I

A steroid alkaloid that is 5alpha-pregnane substituted by a N-methylamino group at position 20 and a beta-N-methylbenzamido group at position 3. Isolated from Sarcococca hookeriana, it exhibits antiplasmodial activity and inhibitory activity against cholinesterase.


conessine

A steroid alkaloid that is con-5-enine substituted by a N,N-dimethylamino group at position 3. It has been isolated from the plant species of the family Apocynaceae.


sarcocine

A steroid alkaloid that is pregn-5-ene substituted by a dimethylamino group at position 3beta, a methyl group at position 20S, and an acetyl(methyl)amino group at position 21.


cortistatin D

A member of the class of cortistatins that is cortistatin C in which the hydrogen at position 17 has been replaced by a hydroxy group.


pachyaximine A

A steroid alkaloid that is pregn-5-ene substituted by a methoxy group at position 3beta, a methyl group at position 20S, and a dimethylamino group at position 21.


cortistatin E

A member of the class of cortistatins that is substituted by a dimethylamino group at the 3alpha position and a (2R)-4-(1,3-dimethylpiperidin-4-yl)butan-2-yl group at the 17 position, with double bonds at the 1-10 and 9-19 positions (the 3R,5R,17beta enantiomer).


wrightiamine A

A steroid alkaloid isolated from Wrightia javanica and has been shown to exhibit antineoplastic activity.


HOOKERIANAMIDE K

A steroid alkaloid that is pregn-4,14-diene substituted by N-dimethylamino groups at positions 3 and 20 (the 3beta,20S stereoisomer). Isolated from Sarcococca hookeriana, it exhibits antileishmanial and antibacterial activities.


A steroid alkaloid that consists of tomatine which has undergone formal dehydrogenation across positions 5 and 6. Found in tomatoes.


sarcodine

A steroid alkaloid that is 5alpha-pregnane substituted by a dimethylamino group at position 3beta, a methyl group at position 20S, and an acetyl(methyl)amino group at position 21.


isosarcodine

A steroid alkaloid that is 5alpha-pregnane substituted by an acetyl(methyl)amino group at position 3beta, a methyl group at position 20S, and a dimethylamino group at position 21.


cortistatins

Any member of a class of steroidal alkaloids obtained from the marine sponge Corticium simplex, with a basic skeleton that is (5R,8beta)-5,8-epoxy-9,19-cyclo-9,10-secoandrostane, bearing a dimethylamino substituent at position 3 and an isoquinolin-7-yl or isoquinolin-7-yl-derived substituent at position 17. They selectively inhibit proliferation of human umbilical vein endothelial cells (HUVECs).


HOOKERIANAMIDE H

A steroid alkaloid that is 5alpha-pregn-2-ene-4-one substituted by a N-formylamino group at position 3 and a N,N-dimethylamino group at position 20. Isolated from Sarcococca hookeriana, it exhibits antiplasmodial activity and inhibitory activity against cholinesterase.


esculeoside A

A steroid saponin that is spirosolane-3,23,27-triol in which the hydroxy group at position 23 is acetylated and the hydroxy groups at positions 3 and 27 are glycosylated by lycotetraosyl and a beta-D-glucopyranosyl moieties respectively. Isolated from the fruits of Lycopersicon esculentum, it exhibits cytotoxic activity.


TOMATINE

A steroid alkaloid that is tomatidine in which the hydroxy group at position 3 is linked to lycotetraose, a tetrasaccharide composed of two units of D-glucose, one unit of D-xylose, and one unit of D-galactose.


HOOKERIANAMIDE J

A steroid alkaloid that is 5alpha-preg-16-ene substituted by a hydroxy group at position 4, a N,N-dimethylamino group at position 20 and a N-senecoylamino group at position 3 (the 3beta,4beta,20S stereoisomer). Isolated from Sarcococca hookeriana, it exhibits antileishmanial and antibacterial activities.


cortistatin C

A member of the class of cortistatins that is cortistatin A in which the hydrogens at position 16 have been replaced by an oxo group.


cortistatin B

A member of the class of cortistatins that is cortistatin A in which the hydrogen at the 16beta position has been replaced by a hydroxy group.


Stage IIIa Penile Cancer AJCC v7

description: Stage IIIa includes: T1-3, N1, M0.  T1: Tumor invades subepithelial connective tissue without lymph vascular invasion and is not poorly differentiated (i.e., grade 3-4) or tumor invades subepithelial connective tissue with lymph vascular invasion or is poorly differentiated.  T2: Tumor invades corpus spongiosum or cavernosum.  T3: Tumor invades urethra.  cN1: Palpable mobile unilateral inguinal lymph node.  pN1: Metastasis in a single inguinal lymph node.  M0: No distant metastasis. (AJCC 7th ed.)


Penile Cancer by AJCC v7 Stage

description: A term that refers to the staging of penile carcinoma according to the American Joint Committee on Cancer, 7th edition.


Stage IIIb Penile Cancer AJCC v7

description: Stage IIIb includes: T1-3, N2, M0.  T1: Tumor invades subepithelial connective tissue without lymph vascular invasion and is not poorly differentiated (i.e., grade 3-4) or tumor invades subepithelial connective tissue with lymph vascular invasion or is poorly differentiated.  T2: Tumor invades corpus spongiosum or cavernosum.  T3: Tumor invades urethra.  cN2: Palpable mobile multiple or bilateral inguinal lymph nodes. pN2: Metastasis in multiple or bilateral superficial inguinal lymph nodes.  M0: No distant metastasis. (AJCC 7th ed.)


Stage IV Penile Cancer AJCC v7

description: Stage IV includes: (T4, Any N, M0); (Any T, N3, M0); (Any T, Any N, M1).  T4: Tumor invades other adjacent structures.  cN3: Palpable fixed inguinal nodal mass or pelvic lymphadenopathy unilateral or bilateral.  pN3: Extranodal extension of lymph node metastasis or pelvic lymph node(s) unilateral or bilateral.  M0: No distant metastasis. M1: Distant metastasis (lymph node metastasis outside of the true pelvis in addition to visceral or bone sites).  (AJCC 7th ed.)


Stage II Penile Cancer AJCC v7

description: Stage II includes: (T1b, N0, M0); (T2, N0, M0); (T3, N0, M0).  T1b: Tumor invades subepithelial connective tissue with lymph vascular invasion or is poorly differentiated.  T2: Tumor invades corpus spongiosum or cavernosum.  T3: Tumor invades urethra.  cN0: No palpable or visibly enlarged inguinal lymph nodes.  pN0: No regional lymph node metastasis.  M0: No distant metastasis. (AJCC 7th ed.)


Stage I Penile Cancer AJCC v7

description: Stage I includes: T1a, N0, M0.  T1a: Tumor invades subepithelial connective tissue without lymph vascular invasion and is not poorly differentiated (i.e., grade 3-4).  cN0: No palpable or visibly enlarged inguinal lymph nodes.  pN0: No regional lymph node metastasis.  M0: No distant metastasis.  (AJCC 7th ed.)


Stage III Penile Cancer AJCC v7

description: Stage III includes: IIIa (T1-3, N1, M0); IIIb (T1-3, N2, M0).  T1: Tumor invades subepithelial connective tissue without lymph vascular invasion and is not poorly differentiated (i.e., grade 3-4) or tumor invades subepithelial connective tissue with lymph vascular invasion or is poorly differentiated.  T2: Tumor invades corpus spongiosum or cavernosum.  T3: Tumor invades urethra.  cN1: Palpable mobile unilateral inguinal lymph node.  pN1: Metastasis in a single inguinal lymph node.  cN2: Palpable mobile multiple or bilateral inguinal lymph nodes. pN2: Metastasis in multiple or bilateral superficial inguinal lymph nodes.  M0: No distant metastasis. (AJCC 7th ed.)


Stage 0 Penile Cancer AJCC v7

description: Stage 0 includes: (Tis, N0, M0); (Ta, N0, M0).  Tis: Carcinoma in situ.  Ta: Non-invasive verrucous carcinoma.  cN0: No palpable or visibly enlarged inguinal lymph nodes.  pN0: No regional lymph node metastasis.  M0: No distant metastasis. (AJCC 7th ed.)


name: calcium-activated potassium channel slowpoke isoform N (fruit fly)

description: A calcium-activated potassium channel slowpoke (fruit fly) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q03720-1.


name: striated muscle preferentially expressed protein kinase isoform h3 (human)

description: A striated muscle preferentially expressed protein kinase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q15772-4.


name: SPEG_HUMAN Striated muscle preferentially expressed protein kinase (sprot)

description: A striated muscle preferentially expressed protein kinase that is encoded in the genome of human.


name: striated muscle preferentially expressed protein kinase isoform h2 (human)

description: A striated muscle preferentially expressed protein kinase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q15772-3.


name: striated muscle preferentially expressed protein kinase isoform h1 (human)

description: A striated muscle preferentially expressed protein kinase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q15772-1.


name: striated muscle preferentially expressed protein kinase isoform h4 (human)

description: A striated muscle preferentially expressed protein kinase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q15772-5.


name: zinc finger MYM-type protein 4 isoform m2 (mouse)

description: A zinc finger MYM-type protein 4 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:A2A791-2.


name: PLCA_MOUSE 1-acyl-sn-glycerol-3-phosphate acyltransferase alpha (sprot)

description: A 1-acyl-sn-glycerol-3-phosphate acyltransferase alpha that is encoded in the genome of mouse.


name: immunoglobulin heavy constant delta O-glycosylated 2 (human)

description: An immunoglobulin heavy constant delta (human) that has been O-glycosylated at the residue equivalent to Thr-113 of the amino acid sequence represented by UniProtKB:P01880-2, in which the glycan composition is represented by GlyTouCan:G29068FM. Example: UniProtKB:P01880-2, Thr-113, MOD:00005~GNO:G29068FM.


name: microfibrillar-associated protein 2 isoform A' (human)

description: A microfibrillar-associated protein 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P55001-2.


name: ODAD4_MOUSE Outer dynein arm-docking complex subunit 4 (sprot)

description: An outer dynein arm-docking complex subunit 4 that is encoded in the genome of mouse.


L-threo-isocitric acid

The (1S,2R)-stereoisomer of isocitric acid.


name: ubiquitin-associated protein 2-like isoform 3 (mouse)

description: A ubiquitin-associated protein 2-like isoform 3 that is encoded in the genome of mouse.


A 1,2-diacyl-sn-glycerol in which the 1-acyl group is specified as oleoyl.


cellular response to amitrole

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amitrole stimulus.


name: F-box protein PP2-A13 isoform 1 (Arabidopsis thaliana)

description: An F-box protein PP2-A13 (Arabidopsis thaliana) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9LEX0-1.


name: protein EXPORTIN 1A isoform 1 (Arabidopsis thaliana)

description: A protein EXPORTIN 1A (Arabidopsis thaliana) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9SMV6-1.


myelofibrosis

description: A partial or complete replacement of the bone marrow stroma by fibrous tissue. It can be a primary bone marrow lesion as part of the chronic myeloproliferative disorders (chronic idiopathic myelofibrosis), a manifestation of acute myeloid leukemia (acute panmyelosis with myelofibrosis), or a secondary phenomenon due to bone marrow involvement by a metastatic tumor (e.g., metastatic breast carcinoma). --2003


name: GONS5_ARATH GDP-mannose transporter GONST5 (sprot)

description: A protein that is a translation product of the GONST5 gene in Arabidopsis thaliana.


name: TF3C5_MOUSE General transcription factor 3C polypeptide 5 (sprot)

description: A general transcription factor 3C polypeptide 5 that is encoded in the genome of mouse.


name: general transcription factor 3C polypeptide 5 isoform m2 (mouse)

description: A general transcription factor 3C polypeptide 5 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8R2T8-2.


name: general transcription factor 3C polypeptide 5 isoform m1 (mouse)

description: A general transcription factor 3C polypeptide 5 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8R2T8-1.


name: sodium/potassium-transporting ATPase subunit beta-2 N-glycosylated 30 (rat)

description: A sodium/potassium-transporting ATPase subunit beta-2 (rat) that has been N-glycosylated at the residue equivalent to Asn-238 of the amino acid sequence represented by UniProtKB:P13638-1, in which the glycan composition is represented by GlyTouCan:G41247ZX. Example: UniProtKB:P13638-1, Asn-238, MOD:00160~GNO:G41247ZX.


homostachydrine

An ammonium betaine that is pipecolic acid zwitterion with methyl groups substituted for the two hydrogens at the nitrogen. It is found in in fruits, seeds, and leaves of orange, lemon, and bergamot.


calponin-2 deaminated 1 (human)

A calponin-2 (human) that has been deaminated on the residue at the position equivalent to Gln-248 of the amino acid sequence represented by UniProtKB:Q99439-1. Example: UniProtKB:Q99439-1, Gln-248, MOD:00685.


regulation of macrophage chemotaxis

description: Any process that modulates the rate, frequency or extent of macrophage chemotaxis. Macrophage chemotaxis is the movement of a macrophage in response to an external stimulus.


regulation of leukocyte chemotaxis

description: Any process that modulates the frequency, rate, or extent of leukocyte chemotaxis.


name: regulation of natural killer cell chemotaxis

description: Any process that modulates the frequency, rate or extent of natural killer cell chemotaxis.


name: negative regulation of macrophage chemotaxis

description: Any process that decreases the rate, frequency or extent of macrophage chemotaxis. Macrophage chemotaxis is the movement of a macrophage in response to an external stimulus.


name: negative regulation of leukocyte chemotaxis

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte chemotaxis.


regulation of monocyte chemotaxis

description: Any process that modulates the frequency, rate, or extent of monocyte chemotaxis.


regulation of eosinophil chemotaxis

description: Any process that modulates the frequency, rate or extent of eosinophil chemotaxis.


name: positive regulation of B cell chemotaxis

description: Any process that activates or increases the frequency, rate or extent of B cell chemotaxis.


name: negative regulation of lymphocyte chemotaxis

description: Any process that stops, prevents or reduces the frequency, rate or extent of lymphocyte chemotaxis.


name: negative regulation of B cell chemotaxis

description: Any process that stops, prevents or reduces the frequency, rate or extent of B cell chemotaxis.


name: positive regulation of myeloid dendritic cell chemotaxis

description: Any process that activates or increases the frequency, rate or extent of myeloid dendritic cell chemotaxis.


name: negative regulation of myeloid dendritic cell chemotaxis

description: Any process that stops, prevents or reduces the frequency, rate or extent of myeloid dendritic cell chemotaxis.


name: positive regulation of lymphocyte chemotaxis

description: Any process that activates or increases the frequency, rate or extent of lymphocyte chemotaxis.


name: positive regulation of mast cell chemotaxis

description: Any process that increases the rate, frequency or extent of mast cell chemotaxis. Mast cell chemotaxis is the movement of a mast cell in response to an external stimulus.


name: positive regulation of macrophage chemotaxis

description: Any process that increases the rate, frequency or extent of macrophage chemotaxis. Macrophage chemotaxis is the movement of a macrophage in response to an external stimulus.


regulation of B cell chemotaxis

description: Any process that modulates the frequency, rate or extent of B cell chemotaxis.


name: regulation of myeloid dendritic cell chemotaxis

description: Any process that modulates the frequency, rate or extent of myeloid dendritic cell chemotaxis.


name: positive regulation of monocyte chemotaxis

description: Any process that increases the frequency, rate, or extent of monocyte chemotaxis.


name: negative regulation of monocyte chemotaxis

description: Any process that decreases the frequency, rate, or extent of monocyte chemotaxis.


name: negative regulation of natural killer cell chemotaxis

description: Any process that stops, prevents or reduces the frequency, rate or extent of natural killer cell chemotaxis.


name: negative regulation of mast cell chemotaxis

description: Any process that decreases the rate, frequency or extent of mast cell chemotaxis. Mast cell chemotaxis is the movement of a mast cell in response to an external stimulus.


name: negative regulation of granulocyte chemotaxis

description: Any process that decreases the rate, frequency or extent of granulocyte chemotaxis. Granulocyte chemotaxis is the movement of a granulocyte in response to an external stimulus.


name: positive regulation of natural killer cell chemotaxis

description: Any process that activates or increases the frequency, rate or extent of natural killer cell chemotaxis.


regulation of T cell chemotaxis

description: Any process that modulates the rate, frequency or extent of T cell chemotaxis. T cell chemotaxis is the directed movement of a T cell in response to an external stimulus.


name: positive regulation of dendritic cell chemotaxis

description: Any process that activates or increases the frequency, rate or extent of dendritic cell chemotaxis.


name: positive regulation of eosinophil chemotaxis

description: Any process that activates or increases the frequency, rate or extent of eosinophil chemotaxis.


name: positive regulation of granulocyte chemotaxis

description: Any process that increases the rate, frequency or extent of granulocyte chemotaxis. Granulocyte chemotaxis is the movement of a granulocyte in response to an external stimulus.


regulation of mast cell chemotaxis

description: Any process that modulates the rate, frequency or extent of mast cell chemotaxis. Mast cell chemotaxis is the movement of a mast cell in response to an external stimulus.


name: negative regulation of dendritic cell chemotaxis

description: Any process that stops, prevents or reduces the frequency, rate or extent of dendritic cell chemotaxis.


name: positive regulation of leukocyte chemotaxis

description: Any process that activates or increases the frequency, rate, or extent of leukocyte chemotaxis.


regulation of granulocyte chemotaxis

description: Any process that modulates the rate, frequency or extent of granulocyte chemotaxis. Granulocyte chemotaxis is the movement of a granulocyte in response to an external stimulus.


regulation of lymphocyte chemotaxis

description: Any process that modulates the frequency, rate or extent of lymphocyte chemotaxis.


regulation of dendritic cell chemotaxis

description: Any process that modulates the frequency, rate or extent of dendritic cell chemotaxis.


name: positive regulation of T cell chemotaxis

description: Any process that increases the rate, frequency or extent of T cell chemotaxis. T cell chemotaxis is the directed movement of a T cell in response to an external stimulus.


name: NCS1_SCHPO Calcium-binding protein NCS-1 (sprot)

description: A protein that is a translation product of the ncs1 gene in Schizosaccharomyces pombe 972h-.


name: macular coloboma-cleft palate-hallux valgus syndrome

description: Macular coloboma-cleft palate-hallux valgus syndrome is characterized by the association of bilateral macular coloboma, cleft palate, and hallux valgus. It has been described in a brother and sister. Pelvic, limb and digital anomalies were also reported. Transmission is autosomal recessive.


2-acylglycerol 22:4

A 2-monoglyceride in which the acyl group contains 22 carbons and 4 double bonds.


monoacylglycerol 22:4

A monoglyceride in which the acyl groups contain a total of 22 carbons and 4 double bonds


1-acylglycerol 22:4

A 1-monoglyceride in which the acyl group contains 22 carbons and 4 double bonds.


name: basic helix-loop-helix ARNT-like protein 2 isoform h3 (human)

description: A basic helix-loop-helix ARNT-like protein 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8WYA1-3.


name: immunoglobulin heavy constant mu isoform h1 N-glycosylated 70 (human)

description: An immunoglobulin heavy constant mu isoform h1 (human) that has been N-glycosylated at the residue equivalent to Asn-440 of the amino acid sequence represented by UniProtKB:P01871-1, in which the glycan composition is represented by GlyTouCan:G41247ZX. UniProtKB:P01871-1, Asn-440, MOD:00160~GNO:G41247ZX.


name: mediator of RNA polymerase II transcription subunit 28 isoform 1 (human)

description: A mediator of RNA polymerase II transcription subunit 28 isoform 1 that is encoded in the genome of human.


name: MED28_HUMAN Mediator of RNA polymerase II transcription subunit 28 (sprot)

description: A mediator of RNA polymerase II transcription subunit 28 that is encoded in the genome of human.


name: mediator of RNA polymerase II transcription subunit 28 isoform 1 phosphorylated 1 (human)

description: A mediator of RNA polymerase II transcription subunit 28 isoform 1 phosphorylated 1 in human. UniProtKB:Q9H204-1, Tyr-64, MOD:00048.


protein SPMIP3 isoform h2 (human)

A protein SPMIP3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q5SVJ3-2.


name: apoptotic process involved in salivary gland cavitation

description: Any apoptotic process in which the solid core of the gland is hollowed out to form the duct.


name: sterol regulatory element-binding protein 1 isoform hSREBP-1C (human)

description: A sterol regulatory element-binding protein 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P36956-3.


name: IF1_BACSU Translation initiation factor IF-1 (sprot)

description: A translation initiation factor IF-1 that is encoded in the genome of Bacillus subtilis subsp. subtilis str. 168.


ephrin receptor 1 isoform b (worm)

An ephrin receptor 1 (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O61460-2.


ephrin receptor 1 isoform a (worm)

An ephrin receptor 1 (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O61460-1.


A sulfoglycolipid in which alpha,alpha-trehalose, sulfated at the 2'-position, is acylated at the 2-position with palmitic acid, and at the 3-position with (2E)-2-methylicos-2-enoic acid.


name: versican core protein O-glycosylated 219 (human)

description: A versican core protein (human) that has been O-glycosylated at the residue equivalent to Thr-2887 of the amino acid sequence represented by UniProtKB:P13611-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P13611-1, Thr-2887, MOD:00005~GNO:G43417UB.


name: collagen alpha-2(XI) chain isoform 5 (human)

description: A collagen alpha-2(XI) chain isoform 5 that is encoded in the genome of human.


collagen alpha-2(XI) chain isoform 5

A collagen alpha-2(XI) chain that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P13942-5 or a 1:1 ortholog thereof.


name: collagen alpha-2(XI) chain isoform 5 (mouse)

description: A collagen alpha-2(XI) chain isoform 5 that is encoded in the genome of mouse.


yellow fever

description: Yellow fever (YF), caused by YF virus, is a zoonotic disease characterized by fever and constitutional symptoms, with the potential to progress to severe and fatal viral hemorrhagic fever with shock and multi-organ system failure.


name: transcription initiation factor TFIID subunit 8 isoform m5 (mouse)

description: A transcription initiation factor TFIID subunit 8 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9EQH4-5.


name: TAF8_MOUSE Transcription initiation factor TFIID subunit 8 (sprot)

description: A transcription initiation factor TFIID subunit 8 that is encoded in the genome of mouse.


name: transcription initiation factor TFIID subunit 8 isoform m2 (mouse)

description: A transcription initiation factor TFIID subunit 8 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9EQH4-2.


name: transcription initiation factor TFIID subunit 8 isoform m3 (mouse)

description: A transcription initiation factor TFIID subunit 8 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9EQH4-3.


name: transcription initiation factor TFIID subunit 8 isoform m1 (mouse)

description: A transcription initiation factor TFIID subunit 8 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9EQH4-1.


name: transcription initiation factor TFIID subunit 8 isoform m4 (mouse)

description: A transcription initiation factor TFIID subunit 8 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9EQH4-4.


name: 7-methylguanosine phosphate-specific 5'-nucleotidase isoform 1 (rat)

description: A 7-methylguanosine phosphate-specific 5'-nucleotidase isoform 1 that is encoded in the genome of rat.


description: The process of coupling tyrosine to tyrosyl-tRNA in a mitochondrion, catalyzed by tyrosyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.


name: ATP-dependent RNA helicase A deaminated 3 (human)

description: An ATP-dependent RNA helicase A (human) that has been deaminated on the residue at the position equivalent to Asn-311 of the amino acid sequence represented by UniProtKB:Q08211-1. Example: UniProtKB:Q08211-1, Asn-311, MOD:00684.


name: positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion

category: biolink:Pathway biolink:OntologyClass biolink:BiologicalProcess biolink:Occurrent biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: Any process that activates, maintains or increases the frequency, rate or extent of skeletal muscle contraction via the regulation of the release of sequestered calcium ion by sarcoplasmic reticulum into cytosol. The sarcoplasmic reticulum is the endoplasmic reticulum of striated muscle, specialised for the sequestration of calcium ions that are released upon receipt of a signal relayed by the T tubules from the neuromuscular junction.


name: regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion

description: Any process that modulates the frequency, rate or extent of cardiac muscle contraction via the regulation of the release of sequestered calcium ion by sarcoplasmic reticulum into cytosol. The sarcoplasmic reticulum is the endoplasmic reticulum of striated muscle, specialised for the sequestration of calcium ions that are released upon receipt of a signal relayed by the T tubules from the neuromuscular junction.


name: regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion

description: Any process that modulates the frequency, rate or extent of skeletal muscle contraction via the regulation of the release of sequestered calcium ion by sarcoplasmic reticulum into cytosol. The sarcoplasmic reticulum is the endoplasmic reticulum of striated muscle, specialised for the sequestration of calcium ions that are released upon receipt of a signal relayed by the T tubules from the neuromuscular junction.


name: negative regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion

description: Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle contraction via the regulation of the release of sequestered calcium ion by sarcoplasmic reticulum into cytosol. The sarcoplasmic reticulum is the endoplasmic reticulum of striated muscle, specialised for the sequestration of calcium ions that are released upon receipt of a signal relayed by the T tubules from the neuromuscular junction.


name: BICD2_HUMAN Protein bicaudal D homolog 2 (sprot)

description: A protein bicaudal D homolog 2 that is encoded in the genome of human.


protein bicaudal D homolog 2

A protein that is a translation product of the human BICD2 gene or a 1:1 ortholog thereof.


name: protein bicaudal D homolog 2 isoform m2 (mouse)

description: A protein bicaudal D homolog 2 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q921C5-2.


name: protein bicaudal D homolog 2 deaminated 2 (human)

description: A protein bicaudal D homolog 2 (human) that has been deaminated on the residue at the position equivalent to Asn-293 of the amino acid sequence represented by UniProtKB:Q8TD16-1. Example: UniProtKB:Q8TD16-1, Asn-293, MOD:00684.


name: protein bicaudal D homolog 2 deaminated 1 (human)

description: A protein bicaudal D homolog 2 (human) that has been deaminated on the residue at the position equivalent to Asn-700 of the amino acid sequence represented by UniProtKB:Q8TD16-1. Example: UniProtKB:Q8TD16-1, Asn-700, MOD:00684.


name: protein bicaudal D homolog 2 isoform m1 (mouse)

description: A protein bicaudal D homolog 2 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q921C5-1.


name: protein bicaudal D homolog 2 isoform h2 (human)

description: A protein bicaudal D homolog 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8TD16-2.


name: protein bicaudal D homolog 2 isoform h1 (human)

description: A protein bicaudal D homolog 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8TD16-1.


name: protein bicaudal D homolog 2 deaminated 3 (human)

description: A protein bicaudal D homolog 2 (human) that has been deaminated on the residue at the position equivalent to Gln-351 of the amino acid sequence represented by UniProtKB:Q8TD16-1. Example: UniProtKB:Q8TD16-1, Gln-351, MOD:00685.


name: BICD2_MOUSE Protein bicaudal D homolog 2 (sprot)

description: A protein bicaudal D homolog 2 that is encoded in the genome of mouse.


name: protein bicaudal D homolog 2 isoform m3 (mouse)

description: A protein bicaudal D homolog 2 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q921C5-3.


F209A_HUMAN Protein FAM209A (sprot)

A protein FAM209A that is encoded in the genome of human.


name: nuclear autoantigen Sp-100 cysteinylated 1 (human)

description: A nuclear autoantigen Sp-100 (human) that has been cysteinylated on the residue at the position equivalent to Cys-629 of the amino acid sequence represented by UniProtKB:P23497-1. Example: UniProtKB:P23497-1, Cys-629, MOD:00765.


name: mitogen-activated protein kinase sma-5 isoform b (worm)

description: A mitogen-activated protein kinase sma-5 (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:G5EBT1-3.


protein TESPA1 isoform h3 (human)

A protein TESPA1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:A2RU30-3.


name: UPF0728 protein C10orf53 isoform h2 (human)

description: A UPF0728 protein C10orf53 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8N6V4-2.


SLIT and NTRK-like protein 1

A protein that is a translation product of the human SLITRK1 gene or a 1:1 ortholog thereof.


name: SLIK1_HUMAN SLIT and NTRK-like protein 1 (sprot)

description: A SLIT and NTRK-like protein 1 that is encoded in the genome of human.


name: SLIT and NTRK-like protein 1, signal peptide removed form (human)

description: A SLIT and NTRK-like protein 1 (human) that has had the signal peptide removed. UniProtKB:Q96PX8, 18-696.


SLIT and NTRK-like protein 1 isoform 1

A SLIT and NTRK-like protein 1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q96PX8-1 or a 1:1 ortholog thereof.


name: SLIT and NTRK-like protein 1 isoform 1 (human)

description: A SLIT and NTRK-like protein 1 isoform 1 that is encoded in the genome of human.


name: SLIK1_MOUSE SLIT and NTRK-like protein 1 (sprot)

description: A SLIT and NTRK-like protein 1 that is encoded in the genome of mouse.


frizzled-7 cysteinylated 1 (mouse)

A frizzled-7 (mouse) that has been cysteinylated on the residue at the position equivalent to Cys-110 of the amino acid sequence represented by UniProtKB:Q61090. UniProtKB:Q61090, Cys-110, MOD:00765.


name: autophagy-related protein 18b isoform 1 (Arabidopsis thaliana)

description: An autophagy-related protein 18b (Arabidopsis thaliana) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8H1Q8-1.


Neuroma of amputation stump

description: A neuroma that occurs at the site of an amputation.


Traumatic neuroma

description: A non-neoplastic proliferation of a nerve caused by injury to the nerve due to trauma or surgery. It presents as a firm nodule that may be associated with pain or tenderness. It most often occurs in the lower extremity following amputation, or in the head and neck region.


Morton neuroma

description: Compressive neuropathy of the forefoot interdigital nerve chiefly due to compression and irritation at the plantar aspect of the transverse intermetatarsal ligament. It is not a true neuroma as the condition is degenerative rather than neoplastic. The most common location for Morton neuroma is between the 2nd and 3rd metatarsals.


Appendix Neuroma

description: A neuroma that arises from the appendix.  It is characterized by a neural spindle cell proliferation that replaces the appendiceal mucosa and lymphoid tissue.  It usually results in the obliteration of the appendiceal lumen.


name: E3 ubiquitin-protein ligase makorin-1 phosphorylated 1 (human)

description: An E3 ubiquitin-protein ligase makorin-1 (human) that has been phosphorylated on the residue at the position equivalent to Ser-109 of the amino acid sequence represented by UniProtKB:Q9UHC7-1. Example: UniProtKB:Q9UHC7-1, Ser-109, MOD:00046.


name: low-density lipoprotein receptor, signal peptide removed form

description: A low-density lipoprotein receptor that has had the signal peptide removed.


name: low-density lipoprotein receptor, signal peptide removed form (human)

description: A low-density lipoprotein receptor (human) that has had the signal peptide removed. UniProtKB:P01130, 22-860.


name: TGF-beta receptor type-2 sequence variant N435S (human)

description: A TGF-beta receptor type-2 (human) that has a Ser residue at the position equivalent to Asn-435 of the amino acid sequence represented by UniProtKB:P37173-1. Example: UniProtKB:P37173-1, Asn-435, CHEBI:29999.


name: diacylglycerol kinase delta isoform h2 (human)

description: A diacylglycerol kinase delta (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q16760-1.


name: T2P2_NEIGO Type II restriction enzyme NgoPII (sprot)

description: A DNA restriction-modification endonuclease that is a translation product of the ngoPIIR gene in Neisseria gonorrhoeae.


name: sodium-dependent neutral amino acid transporter B(0)AT1 sequence variant D173N (human)

description: A sodium-dependent neutral amino acid transporter B(0)AT1 (human) that has an Asn residue at the position equivalent to Asp-173 of the amino acid sequence represented by UniProtKB:Q695T7. UniProtKB:Q695T7, Asp-173, CHEBI:50347.


name: S6A19_HUMAN Sodium-dependent neutral amino acid transporter B(0)AT1 (sprot)

description: A sodium-dependent neutral amino acid transporter B(0)AT1 that is encoded in the genome of human.


name: sodium-dependent neutral amino acid transporter B(0)AT1 sequence variant S303L (human)

description: A sodium-dependent neutral amino acid transporter B(0)AT1 (human) that has a Leu residue at the position equivalent to Ser-303 of the amino acid sequence represented by UniProtKB:Q695T7. UniProtKB:Q695T7, Ser-303, CHEBI:30006.


name: sodium-dependent neutral amino acid transporter B(0)AT1 isoform 1 (human)

description: A sodium-dependent neutral amino acid transporter B(0)AT1 isoform 1 that is encoded in the genome of human.


name: AP-3 complex subunit sigma-1 isoform 1 (mouse)

description: An AP-3 complex subunit sigma-1 isoform 1 that is encoded in the genome of mouse.


name: PKP1_ARATH Plastidial pyruvate kinase 1, chloroplastic (sprot)

description: A protein that is a translation product of the PKP1 gene in Arabidopsis thaliana.


CO4_RAT Complement C4 (sprot)

A complement C4-A that is encoded in the genome of rat.


name: GATOR1 complex protein NPRL2 deaminated 1 (human)

description: A GATOR1 complex protein NPRL2 (human) that has been deaminated on the residue at the position equivalent to Gln-338 of the amino acid sequence represented by UniProtKB:Q8WTW4-1. Example: UniProtKB:Q8WTW4-1, Gln-338, MOD:00685.


GATOR1 complex protein NPRL2

A protein that is a translation product of the human NPRL2 gene or a 1:1 ortholog thereof.


name: GATOR1 complex protein NPRL2 isoform h2 (human)

description: A GATOR1 complex protein NPRL2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8WTW4-2.


name: NPRL2_HUMAN GATOR1 complex protein NPRL2 (sprot)

description: A GATOR1 complex protein NPRL2 that is encoded in the genome of human.


name: GATOR1 complex protein NPRL2 isoform 1 (mouse)

description: A GATOR1 complex protein NPRL2 isoform 1 that is encoded in the genome of mouse.


GATOR1 complex protein NPRL2 isoform 1

A GATOR1 complex protein NPRL2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8WTW4-1 or a 1:1 ortholog thereof.


name: GATOR1 complex protein NPRL2 isoform 1 (human)

description: A GATOR1 complex protein NPRL2 isoform 1 that is encoded in the genome of human.


name: NPRL2_DROME GATOR complex protein NPRL2 (sprot)

description: A GATOR1 complex protein NPRL2 that is encoded in the genome of fruit fly.


name: NPRL2_MOUSE GATOR1 complex protein NPRL2 (sprot)

description: A GATOR1 complex protein NPRL2 that is encoded in the genome of mouse.


name: NPR2_SCHPO Nitrogen permease regulator 2 homolog (sprot)

description: A GATOR1 complex protein NPRL2 that is encoded in the genome of Schizosaccharomyces pombe 972h-.


name: large ribosomal subunit protein bL9 isoform 1 acetylated 1 (Escherichia coli K-12)

description: A large ribosomal subunit protein bL9 isoform 1 acetylated 1 in Escherichia coli K-12. UniProtKB:P0A7R1-1, Lys-89, MOD:00064.


name: large ribosomal subunit protein bL9 isoform 1

description: A large ribosomal subunit protein bL9 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P0A7R1-1 or a 1:1 ortholog thereof.


name: large ribosomal subunit protein bL9 isoform 1 unmodified form

description: A large ribosomal subunit protein bL9 isoform 1 that has not been subjected to any co- or post-translational residue modification or peptide bond cleavage.


name: large ribosomal subunit protein bL9 isoform 1 (Escherichia coli K-12)

description: A large ribosomal subunit protein bL9 isoform 1 that is encoded in the genome of Escherichia coli K-12.


name: large ribosomal subunit protein bL9 isoform 1 acetylated 1

description: A large ribosomal subunit protein bL9 isoform 1 that has been acetylated at the position equivalent to Lys-89 of the amino acid sequence represented by UniProtKB:P0A7R1-1. Example: UniProtKB:P0A7R1-1, Lys-89, MOD:00064.


name: receptor-type tyrosine-protein phosphatase epsilon isoform 1 (rat)

description: A receptor-type tyrosine-protein phosphatase epsilon isoform 1 that is encoded in the genome of rat.


name: receptor-type tyrosine-protein phosphatase epsilon isoform 1

description: A receptor-type tyrosine-protein phosphatase epsilon that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P49446-1 or a 1:1 ortholog thereof.


name: receptor-type tyrosine-protein phosphatase epsilon isoform 1 (mouse)

description: A receptor-type tyrosine-protein phosphatase epsilon isoform 1 that is encoded in the genome of mouse.


hereditary spherocytosis type 3

description: Any hereditary spherocytosis in which the cause of the disease is a mutation in the SPTA1 gene.


name: C7C6B3_MOUSE Elk3 transcript variant c (Fragment) (trembl)

description: An ETS domain-containing protein Elk-3 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:C7C6B3.


name: immunoglobulin heavy constant mu N-glycosylated 30 (human)

description: An immunoglobulin heavy constant mu (human) that has been N-glycosylated at the residue equivalent to Asn-272 of the amino acid sequence represented by UniProtKB:P01871-2, in which the glycan composition is represented by GlyTouCan:G12580WI. Example: UniProtKB:P01871-2, Asn-272, MOD:00160~GNO:G12580WI.


teneurin-m isoform B (fruit fly)

A teneurin-m (fruit fly) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O61307-1.


TENM_DROME Teneurin-m (sprot)

A protein that is a translation product of the Ten-m gene in fruit fly.


teneurin-m isoform D (fruit fly)

A teneurin-m (fruit fly) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O61307-2.


name: ribosomal protein S6 kinase delta-1 isoform h1 (human)

description: A ribosomal protein S6 kinase delta-1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q96S38-1.


name: KS6C1_HUMAN Ribosomal protein S6 kinase delta-1 (sprot)

description: A ribosomal protein S6 kinase delta-1 that is encoded in the genome of human.


name: ribosomal protein S6 kinase delta-1 isoform h2 (human)

description: A ribosomal protein S6 kinase delta-1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q96S38-2.


Nasopharyngeal Squamous Papilloma

description: A benign exophytic neoplasm that arises from the nasopharynx.  It is characterized by the presence of a connective tissue core covered by stratified squamous epithelium.


SPN1_SCHPO Septin homolog spn1 (sprot)

A protein that is a translation product of the spn1 gene in Schizosaccharomyces pombe 972h-.


name: DNA repair protein RAD51 homolog 3 methylated 2 (human)

description: A DNA repair protein RAD51 homolog 3 (human) that has been methylated on the residue at the position equivalent to Cys-124 of the amino acid sequence represented by UniProtKB:O43502-1. Example: UniProtKB:O43502-1, Cys-124, MOD:00660.


name: TLH2_SCHPO ATP-dependent DNA helicase tlh2 (sprot)

description: A protein that is a translation product of the tlh2 gene in Schizosaccharomyces pombe 972h-.


name: CRR13_ARATH Putative cysteine-rich repeat secretory protein 13 (sprot)

description: A protein that is a translation product of the CRRSP13 gene in Arabidopsis thaliana.


name: nucleotide-binding oligomerization domain-containing protein 2 isoform m2 (mouse)

description: A nucleotide-binding oligomerization domain-containing protein 2 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8K3Z0-2.


name: nucleotide-binding oligomerization domain-containing protein 2 isoform m1 (mouse)

description: A nucleotide-binding oligomerization domain-containing protein 2 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8K3Z0-1.


name: disintegrin and metalloproteinase domain-containing protein 21

description: A protein that is a translation product of the human ADAM21 gene or a 1:1 ortholog thereof.


name: ADA21_MOUSE Disintegrin and metalloproteinase domain-containing protein 21 (sprot)

description: A disintegrin and metalloproteinase domain-containing protein 21 that is encoded in the genome of mouse.


name: ADA21_HUMAN Disintegrin and metalloproteinase domain-containing protein 21 (sprot)

description: A disintegrin and metalloproteinase domain-containing protein 21 that is encoded in the genome of human.


name: disintegrin and metalloproteinase domain-containing protein 21 methylated 1 (human)

description: A disintegrin and metalloproteinase domain-containing protein 21 (human) that has been methylated on the residue at the position equivalent to Cys-565 of the amino acid sequence represented by UniProtKB:Q9UKJ8. UniProtKB:Q9UKJ8, Cys-565, MOD:00660.


name: transmembrane protein 198 isoform 1 (human)

description: A transmembrane protein 198 isoform 1 that is encoded in the genome of human.


name: TM198_HUMAN Transmembrane protein 198 (sprot)

description: A transmembrane protein 198 that is encoded in the genome of human.


benzylpenicillin catabolic process

description: The chemical reactions and pathways resulting in the breakdown of benzylpenicillin.


antibiotic catabolic process

description: The chemical reactions and pathways resulting in the breakdown of antibiotic, a substance produced by or derived from certain fungi, bacteria, and other organisms, that can destroy or inhibit the growth of other microorganisms.


name: beta-lactam antibiotic catabolic process

description: The chemical reactions and pathways resulting in the breakdown of a beta-lactam antibiotic, any member of a class of natural or semisynthetic antibiotics whose characteristic feature is a strained, four-membered beta-lactam ring. They include the penicillins and many of the cephalosporins.


penicillin catabolic process

description: The chemical reactions and pathways resulting in the breakdown of any antibiotic that contains the condensed beta-lactamthiazolidine ring system.


bacteriocin catabolic process

description: The chemical reactions and pathways resulting in the breakdown of a bacteriocin, any of a heterogeneous group of polypeptide antibiotics that are secreted by certain bacterial strains and are able to kill cells of other susceptible (frequently related) strains after adsorption at specific receptors on the cell surface. They include the colicins, and their mechanisms of action vary.


exogenous antibiotic catabolic process

description: The chemical reactions and pathways resulting in the breakdown of an antibiotic that has originated externally to the cell or organism.


endogenous antibiotic catabolic process

description: The chemical reactions and pathways resulting in the breakdown of an antibiotic that has originated internally within the cell or organism.


cephamycin C catabolic process

description: The chemical reactions and pathways resulting in the breakdown of cephamycin C.


peptide antibiotic catabolic process

description: The chemical reactions and pathways resulting in the breakdown of peptides with antibiotic activity.


name: neurogenic differentiation factor 6 isoform 1

description: A neurogenic differentiation factor 6 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q96NK8-1 or a 1:1 ortholog thereof.


name: neurogenic differentiation factor 6 isoform 1 (human)

description: A neurogenic differentiation factor 6 isoform 1 that is encoded in the genome of human.


name: neurogenic differentiation factor 6 isoform 1 (mouse)

description: A neurogenic differentiation factor 6 isoform 1 that is encoded in the genome of mouse.


name: ankyrin repeat domain-containing protein 10 isoform h2 (human)

description: An ankyrin repeat domain-containing protein 10 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9NXR5-2.


name: ANR10_HUMAN Ankyrin repeat domain-containing protein 10 (sprot)

description: An ankyrin repeat domain-containing protein 10 that is encoded in the genome of human.


name: ankyrin repeat domain-containing protein 10 methylated 2 (human)

description: An ankyrin repeat domain-containing protein 10 (human) that has been methylated on the residue at the position equivalent to Cys-183 of the amino acid sequence represented by UniProtKB:Q9NXR5-1. Example: UniProtKB:Q9NXR5-1, Cys-183, MOD:00660.


name: ankyrin repeat domain-containing protein 10 deaminated 2 (human)

description: An ankyrin repeat domain-containing protein 10 (human) that has been deaminated on the residue at the position equivalent to Asn-195 of the amino acid sequence represented by UniProtKB:Q9NXR5-1. Example: UniProtKB:Q9NXR5-1, Asn-195, MOD:00684.


name: ankyrin repeat domain-containing protein 10 methylated 1 (human)

description: An ankyrin repeat domain-containing protein 10 (human) that has been methylated on the residue at the position equivalent to Cys-107 of the amino acid sequence represented by UniProtKB:Q9NXR5-1. Example: UniProtKB:Q9NXR5-1, Cys-107, MOD:00660.


name: ankyrin repeat domain-containing protein 10 deaminated 1 (human)

description: An ankyrin repeat domain-containing protein 10 (human) that has been deaminated on the residue at the position equivalent to Asn-85 of the amino acid sequence represented by UniProtKB:Q9NXR5-1. Example: UniProtKB:Q9NXR5-1, Asn-85, MOD:00684.


name: ankyrin repeat domain-containing protein 10 cysteinylated 1 (human)

description: An ankyrin repeat domain-containing protein 10 (human) that has been cysteinylated on the residue at the position equivalent to Cys-183 of the amino acid sequence represented by UniProtKB:Q9NXR5-1. Example: UniProtKB:Q9NXR5-1, Cys-183, MOD:00765.


name: ankyrin repeat domain-containing protein 10 isoform h1 (human)

description: An ankyrin repeat domain-containing protein 10 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9NXR5-1.


name: claudin domain-containing protein 1 deaminated 3 (human)

description: A claudin domain-containing protein 1 (human) that has been deaminated on the residue at the position equivalent to Asn-72 of the amino acid sequence represented by UniProtKB:Q9NY35-1. Example: UniProtKB:Q9NY35-1, Asn-72, MOD:00684.


name: CLDN1_HUMAN Claudin domain-containing protein 1 (sprot)

description: A claudin domain-containing protein 1 that is encoded in the genome of human.


name: claudin domain-containing protein 1 isoform h2 (human)

description: A claudin domain-containing protein 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9NY35-2.


name: claudin domain-containing protein 1 isoform h1 (human)

description: A claudin domain-containing protein 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9NY35-1.


name: claudin domain-containing protein 1 deaminated 4 (human)

description: A claudin domain-containing protein 1 (human) that has been deaminated on the residue at the position equivalent to Asn-124 of the amino acid sequence represented by UniProtKB:Q9NY35-1. Example: UniProtKB:Q9NY35-1, Asn-124, MOD:00684.


name: claudin domain-containing protein 1 cysteinylated 1 (human)

description: A claudin domain-containing protein 1 (human) that has been cysteinylated on the residue at the position equivalent to Cys-106 of the amino acid sequence represented by UniProtKB:Q9NY35-1. Example: UniProtKB:Q9NY35-1, Cys-106, MOD:00765.


name: claudin domain-containing protein 1 deaminated 2 (human)

description: A claudin domain-containing protein 1 (human) that has been deaminated on the residue at the position equivalent to Asn-207 of the amino acid sequence represented by UniProtKB:Q9NY35-1. Example: UniProtKB:Q9NY35-1, Asn-207, MOD:00684.


name: claudin domain-containing protein 1 deaminated 1 (human)

description: A claudin domain-containing protein 1 (human) that has been deaminated on the residue at the position equivalent to Asn-126 of the amino acid sequence represented by UniProtKB:Q9NY35-1. Example: UniProtKB:Q9NY35-1, Asn-126, MOD:00684.


name: claudin domain-containing protein 1 methylated 1 (human)

description: A claudin domain-containing protein 1 (human) that has been methylated on the residue at the position equivalent to Cys-139 of the amino acid sequence represented by UniProtKB:Q9NY35-1. Example: UniProtKB:Q9NY35-1, Cys-139, MOD:00660.


name: claudin domain-containing protein 1 isoform h3 (human)

description: A claudin domain-containing protein 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9NY35-3.


name: claudin domain-containing protein 1 methylated 2 (human)

description: A claudin domain-containing protein 1 (human) that has been methylated on the residue at the position equivalent to Cys-106 of the amino acid sequence represented by UniProtKB:Q9NY35-1. Example: UniProtKB:Q9NY35-1, Cys-106, MOD:00660.


name: Y1705_ARATH Uncharacterized protein At1g27050 (sprot)

description: A protein that is a translation product of the At1g27050 gene in Arabidopsis thaliana.


name: SDR3B_ARATH Short-chain dehydrogenase reductase 3b (sprot)

description: A protein that is a translation product of the SDR3b gene in Arabidopsis thaliana.


phosphopentomutase isoform h1 (human)

A phosphopentomutase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q96G03-1.


GPN3_CANAL GPN-loop GTPase 3 (sprot)

A GPN-loop GTPase 3 that is encoded in the genome of Candida albicans SC5314.


name: TR112_DICDI Multifunctional methyltransferase subunit TRM112-like protein (sprot)

description: A multifunctional methyltransferase subunit TRM112-like protein that is encoded in the genome of Dictyostelium discoideum.


name: cytoplasm protein quality control by the ubiquitin-proteasome system

description: The chemical reactions and pathways resulting in the breakdown of misfolded proteins in the cytoplasm, which are targeted to cytoplasmic proteasomes for degradation.


dynamin-2 isoform 1 (rat)

A dynamin-2 isoform 1 that is encoded in the genome of rat.


vitexin 2''-O-alpha-L-rhamnoside

A derivative of vitexin having an alpha-L-rhamnosyl residue attached at the 2''-position of the glucitol moiety.


name: krueppel-like factor 4 isoform h2 (human)

description: A krueppel-like factor 4 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O43474-1.


name: YEBQ_ECOLI Uncharacterized transporter YebQ (sprot)

description: An uncharacterized transporter YebQ that is encoded in the genome of Escherichia coli K-12.


name: zinc finger protein GLIS3 isoform h2 (human)

description: A zinc finger protein GLIS3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8NEA6-2.


name: nuclear mitotic apparatus protein 1 phosphorylated 2 (human)

description: A nuclear mitotic apparatus protein 1 (human) that has been phosphorylated on the residue at the position equivalent to Thr-2055 of the amino acid sequence represented by UniProtKB:Q14980-1. Example: UniProtKB:Q14980-1, Thr-2055, MOD:00047.


Locally Advanced Chondrosarcoma

description: Chondrosarcoma that has spread to nearby tissues or lymph nodes.


pediatric mesenchymal chondrosarcoma

description: A mesenchymal chondrosarcoma occurring in children.


synovial chondrosarcoma of joint

description: An extremely rare chondrosarcoma arising from the synovium either as a de novo neoplasm or secondary to synovial chondromatosis.


Central Chondrosarcoma, Grade 2

description: An intermediate-grade chondrosarcoma arising in the medulla of bone.


Maxillofacial Chondrosarcoma

description: A chondrosarcoma that arises in a maxillofacial bone.


name: Central Nervous System Mesenchymal Chondrosarcoma

description: A mesenchymal chondrosarcoma that arises from the central nervous system.


Chondrosarcoma, Grade 1

description: A locally aggressive, low grade chondrosarcoma arising in the medulla of bone or within the cartilaginous cap of a pre-existing osteochondroma in the axial skeleton.


Chondrosarcoma, grade 2

description: An intermediate-grade chondrosarcoma arising in the medulla of bone or within the cartilaginous cap of a pre-existing osteochondroma. It is characterized by the presence of increased cellularity and a greater degree of nuclear atypia and hyperchromasia as compared to grade 1 chondrosarcoma. Mitotic activity is present.


name: Secondary Peripheral Chondrosarcoma, Grade 3

description: A high-grade chondrosarcoma arising within the cartilaginous cap of a pre-existing osteochondroma.


Central Chondrosarcoma, Grade 3

description: A high-grade chondrosarcoma arising in the medulla of bone.


name: Secondary Peripheral Atypical Cartilaginous Tumor/Chondrosarcoma, Grade 1

description: A locally aggressive, low-grade chondrosarcoma arising within the cartilaginous cap of a pre-existing osteochondroma. Tumors in the appendicular skeleton are called peripheral atypical cartilaginous tumors and tumors in the axial skeleton are called peripheral chondrosarcomas, grade 1.


Childhood Chondrosarcoma

description: A rare chondrosarcoma that occurs during childhood.


mesenchymal chondrosarcoma

description: A morphologic variant of chondrosarcoma arising from bone and soft tissue. It is characterized by the presence of malignant small round cells, biphasic growth pattern, and well differentiated hyaline cartilage. Clinical presentation includes pain and swelling. The clinical course is aggressive, with local recurrences and distant metastases.


name: Unresectable Primary Central Chondrosarcoma

description: Primary central chondrosarcoma that is not amenable to surgical resection.


name: Locally Advanced Unresectable Primary Central Chondrosarcoma

description: A primary central chondrosarcoma that has spread from its original site of growth to nearby tissues and is not amenable to surgical resection.


localized chondrosarcoma

description: A non-disseminated skeletal or extraskeletal chondrosarcoma.


dedifferentiated chondrosarcoma

description: An aggressive morphologic variant of chondrosarcoma. It is composed of a low grade chondrosarcoma and a high grade non-cartilagenous sarcomatous component. Due to the aggressive nature of the disease, its prognosis is poor.


name: Childhood Primary Central Chondrosarcoma

description: A rare primary central chondrosarcoma that occurs during childhood.


description: A mesenchymal chondrosarcoma that arises in a maxillofacial bone.


Chondrosarcoma recurrent

description: The reemergence of chondrosarcoma after a period of remission.


Chondrosarcoma, grade 3

description: A high-grade chondrosarcoma arising in the medulla of bone or within the cartilaginous cap of a pre-existing osteochondroma. It is characterized by the presence of increased cellularity and a greater degree of nuclear atypia, hyperchromasia, and mitotic activity as compared to grade 2 chondrosarcoma.


Secondary Peripheral Chondrosarcoma

description: A chondrosarcoma arising within the cartilaginous cap of a pre-existing osteochondroma.


periosteal chondrosarcoma

description: A chondrosarcoma arising from the surface of bone. It is characterized by a lobulated growth pattern, high mitotic activity, myxoid stroma formation, and necrotic changes. It occurs in adults. Clinical presentation includes pain, and sometimes swelling.


name: Secondary Central Atypical Cartilaginous Tumor/Chondrosarcoma, Grade 1

description: Central atypical cartilaginous tumor/chondrosarcoma, grade 1 arising in the medulla of bone in association with a pre-existing enchondroma.


Laryngeal chondrosarcoma

description: A chondrosarcoma that arises from hyaline cartilage of the larynx.


Secondary Chondrosarcoma

description: A chondrosarcoma that arises either in a pre-existing enchondroma or within the cartilaginous cap of a pre-existing osteochondroma.


name: Central Atypical Cartilaginous Tumor/Chondrosarcoma, Grade 1

description: A locally aggressive, low-grade chondrosarcoma arising in the medulla of bone. Tumors in the appendicular skeleton are called central atypical cartilaginous tumors and tumors in the axial skeleton are called central chondrosarcomas, grade 1. Tumors arising in the medulla of the bone without a benign precursor are called primary central atypical cartilaginous tumors/chondrosarcomas, grade 1. Tumors arising in the medulla of the bone in association with a pre-existing enchondroma are called secondary central atypical cartilaginous tumors/chondrosarcomas, grade 1.


clear cell chondrosarcoma

description: A rare, usually low grade chondrosarcoma characterized by the presence of tumor cells with clear cytoplasm. It usually arises in the epiphyseal ends of long bones.


Secondary Central Chondrosarcoma

description: A chondrosarcoma that arises in a pre-existing enchondroma.


name: Metastatic Primary Central Chondrosarcoma

description: Primary central chondrosarcoma that has spread from its original site of growth to other anatomic sites.


name: Secondary Peripheral Chondrosarcoma, Grade 1

description: A locally aggressive, low-grade chondrosarcoma arising within the cartilaginous cap of a pre-existing osteochondroma in the axial skeleton.


name: Secondary Peripheral Chondrosarcoma, Grade 2

description: An intermediate-grade chondrosarcoma arising within the cartilaginous cap of a pre-existing osteochondroma.


Chondrosarcoma metastatic

description: A chondrosarcoma that has spread to a secondary anatomical site.


Central Chondrosarcoma, Grade 1

description: A locally aggressive, low-grade chondrosarcoma arising in the medulla of bone in the axial skeleton.