name: adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process

description: The series of molecular signals beginning with a G protein-coupled adrenergic cell surface receptor combining with epinephrine or norepinephrine, to activate adenylate cyclase, which contributes to a circulatory system process carried out by the heart.


Eosinophilopenia

category: biolink:Disease biolink:DiseaseOrPhenotypicFeature biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing

description: Abnormally low level of eosinophils in the blood.


leukemoid reaction

description: A hematology test result that indicates the presence of an increased white blood cell count and increased neutrophil precursors resembling leukemia, in a peripheral blood smear.


myelophthisic anemia

description: A laboratory test result indicating an abnormal amount of circulating nucleated red blood cells and immature red blood cells.


Horner syndrome, horse

description: Horner syndrome that occurs in horse.


fatty acyl-CoA reductase 1 upregulation

description: A disorder of plasmalogens biosynthesis, that is an autosomal dominant neurological disorder that results in uncontrolled synthesis of ether lipids.


fatty acyl-CoA reductase defects

description: Any disorder of plasmalogen biosynthesis in which the cause of the disease is a mutation in the FAR1 gene.


phosphatidylcholine O-42:5

An alkyl,acyl-sn-glycero-3-phosphocholine in which the alkyl or acyl groups at positions 1 and 2 contain a total of 42 carbons and 5 double bonds.


alpha-mycolic acid

A mycolic acid produced by Mycobacterium tuberculosis. Its structure is that of hexacosanoic acid substituted at position 2 by a 1-hydroxy-16-{2-[14-(2-octadecylcyclopropyl)tetradecyl]cyclopropyl}hexadecyl group.


name: positive regulation of cytokine activity

category: biolink:BiologicalProcess biolink:Occurrent biolink:OntologyClass biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: Any process that increases the rate, frequency or extent of the activity of a molecule that controls the survival, growth, differentiation and effector function of tissues and cells.


response to symbiotic bacterium

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a symbiotic bacterium, a bacterium living in close physical association with another organism.


A 3-oxo Delta(4)-steroid that is estr-4-ene substituted by a beta-hydroxy group at position 17 and an alpha-methyl group at position 2.


A  substituted aniline that is a benzene ring substituted with an amino group at position 1 and a trifluoromethyl group at position 4.


aminochromene

Any chromene bearing one or more substituted or unsubstituted amino groups.


A member of the class of chromenes that is 4H-chromene substituted by amino, cyano, 3-nitrophenyl, and dimethylamino groups at positions 2, 3, 4 and 7, respectively. It exhibits anti-cancer activity.


An iminium betaine that consists of 4-{2-[7-(diethylamino)-2-oxo-2H-chromen-3-yl]ethenyl}pyridine-3-sulfonate carryiing a 5-carboxypentyl substituent on the pyridine nitrogen.


A member of the class of chromenes that is 4H-chromene substituted by amino, cyano, 2-methoxyphenyl, and dimethylamino groups at positions 2, 3, 4 and 7, respectively. It exhibits anti-angiogenic activity.


Cicatrix, Hypertrophic

description: A permanent mark on the skin caused by deposits of excessive amounts of collagen during wound healing. It is elevated and does not extend beyond the original boundaries of the wound; the elevation may stabilize or regress spontaneously.


age-related macular degeneration

description: Age-related loss of vision in the central portion of the retina (macula), secondary to retinal degeneration.


age related macular degeneration 4

description: Any age-related macular degeneration in which the cause of the disease is a mutation in the CFH gene.


age related macular degeneration 13

description: An inherited susceptibility or predisposition to developing age related macular degeneration in which the cause of the disease is a mutation in the CFI gene.


name: amyloid-beta clearance by cellular catabolic process

description: The process in which amyloid-beta is removed from extracellular brain regions by cell surface receptor-mediated endocytosis, followed by intracellular degradation.


melioidosis

description: An infection that is caused by Burkholderia pseudomallei, which is found in soil and water; symptoms vary widely, but most commonly include fever, cough, pneumonia, arthralgia, myalgia, and skin ulceration.


mitochondrial mRNA 5'-end processing

description: Any process involved in forming the mature 5' end of an mRNA molecule that derives from the mitochondrial genome.


name: response to cytokinesis checkpoint signaling

description: A process that occurs in response to signals generated as a result of cytokinesis checkpoint signaling.


An amino tetrasaccharide comprised of a linear sequence of beta-D-galactose, N-acetyl-beta-D-glucosamine, beta-D-galactose and N-acetyl-beta-D-glucosamine residues linked (1->4), (1->6) and (1->4).


rosoxacin

A quinolinemonocarboxylic acid that is 1,4-dihydroquinoline-3-carboxylic acid that is substituted by an ethyl group at position 1 and by a pyridin-4-yl group at position 7. An antibacterial drug, active against Neisseria gonorrhoeae, it has been used for treating urinary tract infections and certain sexually transmitted diseases.


A  trimethoxyflavone that is tricin in which the hydroxy group at position 7 has been replaced by a methoxy group. It has been isolated from the stems of Sinocalamus affinis.


name: Mixed phenotype acute leukemia T/myeloid

description: A rare mixed phenotype acute leukemia in which the blasts express T-lymphoid and myeloid lineage markers but are negative for KMT2A rearrangement and t(9;22)(q34;q11.2) translocation. The prognosis is usually unfavorable.


SUCCINYLACETONE

A dioxo monocarboxylic acid that is heptanoic acid in which oxo groups replace the hydrogens at positions 4 and 6. It is an abnormal metabolite of the tyrosine metabolic pathway and a marker for type 1 tyrosinaemia.


RNA polyanion 2',3'-cyclic phosphate

An ionic polymer obtained by global deprotonation of the phosphate OH groups of any RNA terminating in a 2',3'-cyclic phosphate. Major structure at pH 7.3


N-demethylmirtazapine

A benzazepine metabolite resulting from demethylation of the antidpressant, mirtazapine.


BROMOBENZENE

The simplest member of the class of bromobenzenes, that is benzene in which a single hydrogen has been substituted by a bromine. A liquid at room temperature (m.p. -30degreeC; b.p.760 156degreeC), it is used as a solvent, particularly for large-scale crystallisations, and for the introduction of phenyl groups in organic synthesis.


bromoarene

A compound derived from an arene by replacing a hydrogen atom with a bromine atom.


bromobiphenyl

A bromoarene that consists of a biphenyl skeleton substituted by one or more bromo groups.


polybromobiphenyl

A biphenyl compound containing between 2 and 10 bromine atoms attached to the two benzene rings.


monobromobiphenyl

A bromobiphenyl carrying a single bromo substituent at unspecified position.


A polybromobiphenyl that is biphenyl in which the hydrogens at positions 2, 2', 4, 4', 5, and 5' have been replace by bromines.


name: Stage M1 Embryonal Tumor with Multilayered Rosettes

description: Microscopic tumor cells are detected in the cerebrospinal fluid. (Chang CH, Housepian EM, Herbert C. Radiology, 1969; 93(6):1351-9.)


HYDROXYGUANIDINE

A member of the class of guanidines that is guanidine in which one of the hydrogens attached to the nitrogen at position 1 is substituted by a hydroxy group.


renal dysplasia, dog

description: Renal dysplasia that occurs in dog.


name: Prostate Acinar Adenocarcinoma, Atrophic Pattern

description: An unusual variant of acinar prostate adenocarcinoma characterized by the presence of neoplastic small atrophic glands that contain malignant cells with scant cytoplasm.


N-acylserine 18:1

An N-acylserine in which the acyl group contains 18 carbons and 1 double bond.


phosphatidylglycerol 37:0

A phosphatidylglycerol in which the two acyl groups contain 37 carbon atoms and no double bonds


N-(1,2-saturated acyl)sphinganine

Any dihydroceramide having a methylene group adjacent to the ceramide carbonyl group.


ceroid lipofuscinosis, neuronal, 6A

description: A rare condition that affects the nervous system. Signs and symptoms of the condition generally develop between ages 18 months and 8 years, although later onset cases have been reported. Affected people may experience loss of muscle coordination (ataxia), seizures that do not respond to medications, muscle twitches (myoclonus), visual impairment, and developmental regression (loss of previously acquired skills). It occurs predominantly in people of Portuguese, Indian, Pakistani, or Czech ancestry. CLN6-NCL is caused by changes (mutations) in the CLN6 gene and is inherited in an autosomal recessive manner. Treatment options are limited to therapies that can help relieve some of the symptoms.


name: multiple epiphyseal dysplasia, with severe proximal femoral dysplasia

description: Multiple epiphyseal dysplasia, with severe proximal femoral dysplasia is a rare primary bone dysplasia characterized by severe, early-onset dysplasia of the proximal femurs, with almost complete absence of the secondary ossification centers and abnormal development of the femoral necks (short and broad with irregular metaphyses). It is associated with gait abnormality, mild short stature, arthralgia, joint stiffness with limited mobility of the hips and irregular acetabula, and hip and knee pain. Coxa vara and mild spinal changes are also associated.


Prostate cancer stage C

description: Tumor is clinically localized to the periprostatic area, but extends through the prostatic capsule; the seminal vesicles may be involved.


(S)-metamifop

A 2-{4-[(6-chloro-1,3-benzoxazol-2-yl)oxy]phenoxy}-N-(2-fluorophenyl)-N-methylpropanamide that has S-configuration.


A member of the class of 1,3-benzoxazoles that is 6-chloro-1,3-benzoxazol-2-ol in which the hydrogen of the hydroxy group at position 2 is substituted by a 4-({1-[(2-fluorophenyl)(methyl)amino]-1-oxopropan-2-yl}oxy)phenyl group.


metamifop

A 2-{4-[(6-chloro-1,3-benzoxazol-2-yl)oxy]phenoxy}-N-(2-fluorophenyl)-N-methylpropanamide that has R-configuration. It is an inhibitor of acetyl-coenzyme A carboxylase (ACCase) and a postemergence herbicide which exhibits high control efficacy against sensitive weeds, especially Echinochloa crus-galli in paddy fields.


N,O-dioleoylethanolamine

A fatty acid ester obtained by formal condensation of the carboxy group of oleic acid with the hydroxy group of oleoyl ethanolamide.


N,O-diacylethanolamine

Any carboxamide obtained by acylation of both the amino and hydroxy functions of ethanolamine.


name: non-severe combined immunodeficiency due to polymerase delta deficiency

description: Any non-severe combined immunodeficiency in which the cause of the disease is variation in the POLD1/POLD2 gene.


L-alanyl-L-glutamic acid

A dipeptide consisting of L-glutamic acid having an L-alanyl attached to its alpha-amino group


sideretin acetylhexoside

R1=acetylhexoside,R2=H,R3=H; R1=H,R2=acetylhexoside,R3=H; R1=H,R2=H,R3=acetylhexoside


ear neoplasm

description: A neoplasm (disease) that involves the ear.


disorder of ear

description: A disease that involves the ear.


perichondritis of auricle

description: An otitis externa involving infection of the tissue surrounding the cartilage of the earlobe (pinna), ear canal, or both. It may be caused by injury, burns, insect bites, ear piercing, or a boil on the ear. The common bacterial causative agent is Pseudomonas aeruginosa. Symptoms include redness, pain, fever, swelling of the earlobe and pus accumulation between the cartilage and the layer of connective tissue around it.


name: congenital corneal opacities, cornea guttata, and corectopia


tympanic membrane disorder

description: A disease involving the tympanic membrane.


chronic eustachian salpingitis

description: Chronic form of otosalpingitis.


acute perichondritis of pinna

description: Acute form of perichondritis of auricle.


acute infection of pinna

description: An otitis externa which involves bacterial infections often related to underlying comorbidities as well as trauma. Common sources of trauma include ear piercing, boxing, blunt trauma, burns, bite wounds and iatrogenic insults. The common bacterial pathogens are staphylococcal and streptococcal species.


benign neoplasm of middle ear

description: A benign neoplasm that involves the middle ear.


autoimmune inner ear disease

description: A syndrome characterized by rapidly progressive sensorineural hearing loss (SNHL), that is often bilateral, and is potentially reversible.


space motion sickness

description: Disorder characterized by nausea, vomiting, and dizziness, possibly in response to vestibular disorientation or fluid shifts associated with space flight. (From Webster's New World Dictionary)


external ear disorder

description: A disease involving the external ear.


external ear neoplasm

description: A neoplasm (disease) that involves the external ear.


cholesteatoma of external ear

description: A cholesteatoma (disease) that involves the external ear.


polyp of middle ear

description: A benign polypoid growth in the middle ear.


acute eustachian salpingitis

description: Acute form of otosalpingitis.


motion sickness

description: A sensation of discomfort that results from a discordant relationship between visualized movement and any movement sensed by the vestibular system, which is characterized by dizziness, nausea, and vomiting.


chronic fungal otitis externa

description: Chronic form of otomycosis.


tympanitis

description: An inflammatory disease involving a pathogenic inflammatory response in the tympanic membrane.


otomycosis

description: Fungus infection of the external ear, usually by aspergillus species


inner ear disorder

description: A non-neoplastic or neoplastic disorder affecting the inner ear. Causes are inner ear infections, head injuries, and neoplasms (e.g., acoustic schwannoma). Symptoms include dizziness, imbalance, nausea, and vision problems.


external ear lipoma

description: A benign adipose tissue neoplasm of the external ear.


name: chronic tubotympanic suppurative otitis media

description: A suppurative otitis media which is an inflammatory disease of the middle ear cleft characterized by the presence of a persisting perforation within the pars tensa of the tympanic membrane, intermittent profuse muco-purulent otorrhea and gradually progressive conductive hearing loss of more than 12 weeks duration. It is caused by episodes of upper respiratory infections.


chronic tympanitis

description: Chronic form of tympanitis.


ear infection

description: A viral or bacterial infection that affects the external, middle, or inner ear. It may follow an upper respiratory infection. Signs and symptoms include pain, ear discharge, ear fullness, hearing loss, vertigo, nausea, and vomiting.


middle ear disorder

description: A disease involving the middle ear.


acute allergic mucoid otitis media

description: A blue drum syndrome caused by an allergen.


benign neoplasm of ear

description: A benign neoplasm that involves the ear.


myringitis bullosa hemorrhagica

description: A tympanic membrane disease that is characterized by blisters on the eardrum resulting from infection.


name: active cochleovestibular Meniere disease


infectious otitis media

description: Inflammation of the anatomical structures of the middle ear secondary to an infectious process. Bacterial etiology is most common, but both viral and fungal pathogens are also possible. Symptoms include erythema and edema of the tympanic membrane, pain, and possibly fever. In severe infections, inflammation and edema of the structures of the middle ear can lead to perforation of the tympanic membrane secondary to the buildup of pressure in the narrow space.


acute sanguinous otitis media

description: A acute transudative otitis media which involves bloody effusion.


middle ear cancer

description: A malignant neoplasm involving the middle ear


middle ear neuroendocrine tumor

description: A neuroendocrine neoplasm that involves the middle ear.


noxacusis

description: Noxacusis/pain hyperacusis is characterized by individuals who experience otalgia or pain (e.g., dull ache, burning, sharp, stabbing pain and throbbing pain) in response to everyday sounds. This differs clinically from those whose primary symptom is the perception of everyday sounds as excessively loud (termed loudness hyperacusis).


inner ear cancer

description: A malignant neoplasm involving the internal ear.


benign paroxysmal positional vertigo

description: Idiopathic recurrent vertigo associated with positional nystagmus. It is associated with a vestibular loss without other neurological or auditory signs. Unlike in labyrinthitis and vestibular neuronitis inflammation in the ear is not observed.


suppurative otitis media

description: Inflammation of the middle ear with purulent discharge.


chronic perichondritis of pinna

description: Chronic form of perichondritis of auricle.


chronic non-suppurative otitis media

description: Chronic form of non-suppurative otitis media.


eustachian tube disorder

description: A disease involving the pharyngotympanic tube.


internal auditory canal lipoma

description: A rare benign adipose tissue neoplasm of the internal auditory canal, often presenting as an acoustic tumor. It may be intermixed with the vestibulocochlear nerve and may adhere to adjacent structures.


non-suppurative otitis media

description: A otitis media which involves transudation of fluid in the middle ear without pus formation.


internal auditory canal meningioma

description: A meningioma that affects the internal auditory canal.


patulous eustachian tube

description: A eustachian tube disorder with a wider eustachian tube which allows a larger bolus of bacteria-laden material from the nasopharynx during an infection to enter the middle ear, causing a more fulminant infection.


acute serous otitis media

description: A acute transudative otitis media with thin, watery and sterile effusion.


chronic purulent otitis media

description: Otitis media that persists for at least six weeks, and that is associated with otorrhea through a perforated tympanic membrane.


acute transudative otitis media

description: Acute form of non-suppurative otitis media.


polyp of external auditory canal

description: A polyp that involves the external acoustic meatus.


acute allergic sanguinous otitis media

description: A acute sanguinous otitis media caused by an allergen.


external ear cancer

description: A malignant neoplasm involving the external ear.


serous glue ear

description: Chronic form of serous otitis media.


otosalpingitis

description: An inflammatory disease involving a pathogenic inflammatory response in the pharyngotympanic tube.


name: X-linked mixed hearing loss with perilymphatic gusher

description: X-linked mixed deafness with perilymphatic gusher, also known as X-linked deafness type 2, is a rare form of non-syndromic genetic deafnesss affecting males and characterized by pathognomonic inner ear anomalies and conductive and profound sensorineural hearing loss. The inner ear anomalies are described as dilatation of the internal auditory meatus and fistulous connection between the cochlear basal turn and internal auditory canal resulting in perilympatic gusher on attempted mobilization of a fixed stapes. Obligate female carriers may suffer from mild to moderate hearing loss.


vestibular disorder

description: Pathological processes of the vestibular labyrinth which contains part of the balancing apparatus. Patients with vestibular diseases show instability and are at risk of frequent falls.


cholesteatoma of attic

description: A cholesteatoma in the attic


cholesteatoma of middle ear

description: A non-neoplastic lesion characterized by the proliferation of keratinizing squamous epithelium in the middle ear that results in the accumulation of keratin and cells. It is usually caused by repeated infections. If left untreated, it may increase in size and destroy the adjacent delicate bones of the middle ear.


purulent acute otitis media

description: Acute form of suppurative otitis media.


acute otitis externa

description: Acute form of otitis externa.


blue drum syndrome

description: A acute transudative otitis media involving thick, viscid and mucuslike fluid effusion due to which the drum appears blue in color.


cochlear disorder

description: Pathological processes of the snail-like structure (cochlea) of the inner ear (labyrinth) which can involve its nervous tissue, blood vessels, or fluid (endolymph).


malignant otitis externa

description: An otitis externa which involves infection of the external ear that has spread to involve the skull bone containing part of the ear canal, the middle ear, and the inner ear. It is caused by the bacteria Pseudomonas. This is common in people with weakened immune systems and in older people with diabetes.


allergic otitis media

description: A otitis media (disease) with a basis in a pathological type I hypersensitivity reaction.


acute allergic serous otitis media

description: A acute serous otitis media caused by an allergen.


endolymphatic hydrops

description: An accumulation of endolymph in the inner ear (labyrinth) leading to buildup of pressure and distortion of intralabyrinthine structures, such as cochlea and semicircular canals. It is characterized by sensorineural hearing loss; tinnitus; and sometimes vertigo.


chronic atticoantral disease

description: A chronic purulent otitis media which involves perforation in the attic region (pars flaccida of the tympanic membrane) or at the posterosuperior margin, with in-growth of squamous epithelium into the middle ear. This is caused as a result of poor ventilation of the middle ear and episodes of infection.


name: malignant otitis externa caused by Pseudomonas aeruginosa

description: An malignant otitis externa caused by infection with Pseudomonas aeruginosa.


phacogenic glaucoma

description: Secondary glaucoma caused by either excessive size or spheric shape of the lens.


phacolytic glaucoma

description: An abnormal condition characterized by an acute autoimmune reaction of the eye. It is caused by hypersensitivity of the eye to the protein of the crystalline lens and commonly follows trauma to the crystalline lens or cataract surgery. Associated symptoms include swelling and inflammation of the eye, severe pain, and blurred vision. The substance of the lens is invaded by polymorphonuclear cells and mononuclear phagocytes. Accurate diagnosis must differentiate between this condition and infectious endophthalmitis. Therapy is supportive and commonly includes the administration of corticosteroids and atropine. Refractory cases may require surgical removal of the lens.


The 5alpha-stereoisomer of cholestane.


EPIDIHYDROCHOLESTERIN

A 5alpha-chloestane compound having a 3alpha-hydroxy substituent.


name: lactate:proton symporter activity

category: biolink:MolecularActivity biolink:Occurrent biolink:OntologyClass biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: lactate (out) + H+ (out) = lactate (in) + H+ (in).


name: lactate transmembrane transporter activity

description: Enables the transfer of lactate from one side of a membrane to the other. Lactate is 2-hydroxypropanoate, CH3-CHOH-COOH; L(+)-lactate is formed by anaerobic glycolysis in animal tissues, and DL-lactate is found in sour milk, molasses and certain fruit juices.


Colorectal Traditional Serrated Adenoma

description: An adenoma that arises from the colon or rectum.  It is characterized by prominent serration of the glands.


Colon Traditional Serrated Adenoma

description: An adenoma that arises from the colon.  It is characterized by prominent serration of the glands.


Colorectal Filiform Serrated Adenoma

description: A traditional serrated adenoma that arises from the colon or rectum.  It is characterized by the presence of prominent villous projections of the neoplastic epithelium.


name: peptide cross-linking via 2-(S-L-cysteinyl)-L-phenylalanine

description: The cross-linking of a cysteine residue to an L-phenylalanine residue to form 2-(S-L-cysteinyl)-L-phenylalanine.


SEC61A1 deficiency

description: Any Mendelian disease in which the cause of the disease is a mutation in the SEC61A1 gene. It is characterized by variable presentation of phenotypes in patients, including autosomal dominant tubulointerstitial kidney disease, primary antibody deficiency, and severe congenital neutropenia.


name: hyperuricemic nephropathy, familial juvenile type 4

description: Any familial juvenile hyperuricemic nephropathy in which the cause of the disease is a mutation in the SEC61A1 gene.


system development

description: The process whose specific outcome is the progression of an organismal system over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process.


A ceramide that is the N-tetracosanoyl derivative of 4-hydroxyeicosasphinganine.


CMP 5'-end residue

The 5'-end bound-monomer of a cytidylyl-5'-monophosphoric acid that is part of a nucleic acid.


oogenesis

description: The complete process of formation and maturation of an ovum or female gamete from a primordial female germ cell. Examples of this process are found in Mus musculus and Drosophila melanogaster.


oocyte development

description: The process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell.


spermatid development

description: The process whose specific outcome is the progression of a spermatid over time, from its formation to the mature structure.


name: G protein-coupled receptor signaling pathway coupled to cGMP nucleotide second messenger

category: biolink:Pathway biolink:OntologyClass biolink:BiologicalProcess biolink:Occurrent biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: The series of molecular signals generated as a consequence of a G protein-coupled receptor binding to its physiological ligand, followed by activation of guanylyl cyclase (GC) activity and a subsequent increase in the concentration of cyclic GMP (cGMP).


An acetamide compound of general formula RCH2CH2NHC(=O)CH3 where R represents an aryl moiety.


A trivalent inorganic anion obtained by removal of three protons from orthoperiodic acid


perchlorate

A monovalent inorganic anion obtained by deprotonation of perchloric acid.


bromate salt

Any salt that has chlorate, [BrO3](-), as the anionic component.


iodite

A monovalent inorganic anion obtained by deprotonation of iodous acid.


chlorate salt

Any salt that has chlorate, [ClO3](-), as the anionic component.


bromite

A monovalent inorganic anion obtained by deprotonation of bromous acid.


A monovalent inorganic anion obtained by deprotonation of one of the six OH groups in orthoperiodic acid  acid.


hypoiodite

A monovalent inorganic anion obtained by deprotonation of hypoiodous acid.


A divalent inorganic anion obtained by removal of two of the five protons from orthoperiodic acid


periodate

A monovalent inorganic anion obtained by deprotonation of periodic acid.


perbromate

A monovalent inorganic anion obtained by deprotonation of perbromic acid.


hypofluorite

A monovalent inorganic anion obtained by deprotonation of hypofluorous acid.


A monovalent inorganic anion obtained by deprotonation of fluorous acid.


hypobromite

A monovalent inorganic anion obtained by deprotonation of hypobromous acid.


myofibrillar myopathy 3

description: A rare, late adult-onset myofibrillar myopathy characterized by progressive distal muscle weakness associated with peripheral neuropathy and hyporeflexia. Ambulation may be lost within a few years.


name: positive regulation of calcium-mediated signaling involved in cellular response to calcium ion

description: Any positive regulation of calcium-mediated signaling that is involved in cellular response to calcium ion.


methyl 3,5-di-O-caffeoyl quinate

A methyl ester resulting from the formal condensation of the carboxy group of 3,5-di-O-caffeoyl quinic acid with methanol. Isolated from Suaeda glauca and Dichrocephala bicolor, it exhibits hepatoprotective activity.


Penile Glomus Tumor

description: A glomus tumor that occurs in the penis.


Bone Glomus Tumor

description: A benign or malignant glomus tumor arising from the bone.


name: Glomus tumor of uncertain malignant potential

description: A glomus tumor that shows atypical characteristics and has borderline malignant potential.


Solid Glomus Tumor

description: The most common morphologic variant of glomus tumor.  It is characterized by the presence of a nest of glomus cells surrounding capillary sized vessels.


Benign Glomus Tumor

description: A glomus tumor of small size characterized by the absence of nuclear atypia and mitotic activity.


Gastric Glomus Tumor

description: A rare glomus tumor that arises from the stomach.  It is seen in adults, especially women.  The majority of cases follow a benign clinical course.


glomuvenous malformation

description: Glomuvenous malformations (GVMs) are hereditary vascular malformations characterized by the presence of small, multifocal bluish-purple venous lesions involving the skin.


RHAMNOCITRIN

A monomethoxyflavone that is the 7-methyl ether derivative of  kaempferol.


peroxisome biogenesis disorder type 3B

description: A genetic disorder characterized by abnormalities in the breakdown of phytanic acid. It results in accumulation of phytanic acid in the blood, brain and other tissues. Signs and symptoms include retinitis pigmentosa which may lead to blindness, hearing problems and deafness, hypotonia, ataxia, nystagmus, facial deformities, and mental and growth retardation.


name: colominic acid (non-reducing N- or O-acylneuraminyl residue)


polysialic acid

Polymers of sialic acid and derivatives. The degree of polymerization is 8 to 200 Sia residues.


polysialic acid acetylated at O-9

A polysialic acid compound having an O-acetyl group at the 9-position of each repeating unit.


icariside II

A glycosyloxyflavone that is 3,5,7-trihydroxy-4'-methoxy-8-prenylflavone in which the hydroxy group at position 3 has been converted into its alpha-L-rhamnopyranoside.


Stage IVA Ovarian Cancer AJCC v8

description: Stage IVA includes: Any T, Any N, M1a. M1a: Ovarian cancer with pleural effusion with positive cytology. (from AJCC 8th Ed.)


Stage IV Ovarian Cancer AJCC v8

description: Stage IV includes: Any T, Any N, M1: M1: Distant metastasis, including pleural effusion with positive cytology; liver or splenic parenchymal metastasis; metastasis to extra-abdominal organs (including inguinal lymph nodes and lymph nodes outside the abdominal cavity); and transmural involvement of intestine. (from AJCC 8th Ed.)


Stage IVB Ovarian Cancer AJCC v8

description: Stage IVB includes: Any T, Any N, M1b. M1b: Ovarian cancer with liver or splenic parenchymal metastases; metastases to extra-abdominal organs (including inguinal lymph nodes and lymph nodes outside the abdominal cavity); transmural involvement of intestine. (from AJCC 8th Ed.)


smallpox

description: A condition that is caused by infection with Variola, and that is characterized by small, raised bumps.


Modified smallpox

description: Smallpox that occurs in an individual who has been vaccinated.


name: Testicular Germ Cell Neoplasia In Situ with Extratubular Extension

description: A malignant neoplasm that arises from the testis and is characterized by the presence of large germ cells with abundant cytoplasm in the seminiferous tubules, associated with an invasive germ cell tumor in the adjacent tissues.


name: 23S rRNA (guanine(745)-N(1))-methyltransferase activity

description: Catalysis of the reaction: S-adenosyl-L-methionine + guanine(745) in 23S rRNA = N(1)-methylguanine(745) in 23S rRNA + S-adenosyl-L-homocysteine.


trisomy 9p

description: Trisomy 9p is a rare chromosomal anomaly syndrome, resulting from a partial or complete trisomy of the short arm of chromosome 9, with a wide phenotypic variablility, typically characterized by intellectual disability, craniofacial dysmorphism (e.g. microcephaly, large anterior fontanel, hypertelorism, strabismus, downslanting palpebral fissures, malformed, low-set, protruding ears, bulbous nose, macrostomia, down-turned corners of mouth, micrognathia), digital anomalies (brachydactyly and clinodactyly), and short stature. Less frequently patients present with cardiopathy and renal, skeletal, and central nervous system malformations.


A branched amino oligosaccharide that is a nonacosasaccharide derivative comprising a linear trisaccharide of beta-D-mannose and two N-acetyl-beta-D-glucosamine residues (one of which is at the reducing end) all linked in sequence (1->4), to the mannosyl residue of which are linked two beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl linear tridecasaccharide units via (1->3) and (1->6) glycosidic linkages.


5'-end GTP-ribonucleotide(5-) residue

An organic anionic group obtained by deprotonation of the phosphate and triphosphate OH groups of any 5'-end GTP-ribonucleotide residue; major species at pH 7.3.


A very long-chain omega-6 fatty acid that is triacontanoic acid having four double bonds located at positions 15, 18, 21 and 24 (the 15Z,18Z,21Z,24Z-isomer).


N-acetyl-D-hexosamine

Any N-acetylhexosamine in which the hexosamine has D-configuration. The structure provided is an illustrative example of the pyranose form of an N-acetyl-D-hexosamine.


N-acetyl-alpha-D-glucosamine

An N-acetyl-D-glucosamine that has alpha-configuration at the anomeric centre.


hercynyl-SeGlcNAc selenoxide

Major species at pH 7.3


N-acetyl-beta-D-mannosamine

An N-acetyl-D-mannosamine having beta-configuration at its anomeric centre.


N-ACETYLMANNOSAMINE

An N-acetylmannosamine having pyranose form and alpha-D-configuration.


N-acetyl-alpha-D-galactosamine

An N-acetyl-D-galactosamine having alpha-configuration at the anomeric centre.


N-acetyl-D-glucosamine

The D isomer of N-acetylglucosamine.


N-acetyl-D-mannosamine

An N-acetylmannosamine having D-configuration.


name: L-alanine biosynthetic process via ornithine

description: The chemical reactions and pathways resulting in the formation of L-alanine, via the intermediate ornithine.


L-alanine biosynthetic process

description: The chemical reactions and pathways resulting in the formation of L-alanine, the L-enantiomer of 2-aminopropanoic acid, i.e. (2S)-2-aminopropanoic acid.


name: L-alanine biosynthetic process from pyruvate

description: The chemical reactions and pathways resulting in the formation of alanine from other compounds, including pyruvate.


viral head-tail joining

description: Process by which virus heads and tails are attached to each other.


Head and Neck Rhabdomyosarcoma

description: A malignant neoplasm with skeletal muscle differentiation that arises from the head and neck. It usually affects the orbit, eyelid, ear, sinonasal tract, and nasopharynx.


orbit alveolar rhabdomyosarcoma

description: A malignant mesenchymal neoplasm that arises in the orbit. It is characterized by the presence of round cells with myoblastic differentiation and a fibrovascular stroma.


Sinonasal Rhabdomyosarcoma

description: A rhabdomyosarcoma that arises from the nasal cavity and paranasal sinuses.


orbit rhabdomyosarcoma

description: A malignant mesenchymal neoplasm with skeletal muscle differentiation that arises from the orbit.


name: positive regulation of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization

description: Any process that activates or increases the frequency, rate or extent of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization.


name: positive regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization

description: Any process that activates or increases the frequency, rate or extent of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization.


Advanced Rectal Squamous Cell Carcinoma

description: Rectal squamous cell carcinoma that has spread extensively to other anatomic sites or is no longer responding to treatment.


name: Metastatic Rectal Squamous Cell Carcinoma

description: Rectal squamous cell carcinoma that has spread from the original site of growth to other anatomic sites.


name: Locally Advanced Rectal Squamous Cell Carcinoma

description: Rectal squamous cell carcinoma that has spread to nearby tissues or lymph nodes.


DNA topological change

description: The process in which a transformation is induced in the topological structure of a double-stranded DNA helix, resulting in a change in linking number.


mediastinitis

description: An inflammatory process affecting the mediastinum.


(R)-tetrahydropapaverine

The R-enantiomer of tetrahydropapaverine.


(R)-goitrin

A 5-ethenyl-1,3-oxazolidine-2-thione that has R-configuration. It is a constituent of a traditional Chinese herbal medicine, Radix isatidis.


An omega-hydroxy fatty acid ascaroside that is oscr#30 in which the pro-R hydrogen beta to the carboxy group is replaced by a hydroxy group. It is a metabolite of the nematode Caenorhabditis elegans.


A methyl glycoside that is beta-D-galactopyranosyl-(1->4)-2-acetamido-2-deoxy-beta-D-glucopyranose in which the anomeric hydroxy group is replaced by methoxy.


peptidyl-methionine racemization

description: The racemization of peptidyl-methionine.


chiral amino acid racemization

description: The formation of a mixture of the two possible enantiomers from the D- or L-enantiomer of a chiral amino acid.


peptidyl-tryptophan racemization

description: The racemization of peptidyl-tryptophan.


peptidyl-leucine racemization

description: The racemization of peptidyl-leucine.


peptidyl-D-alanine racemization, direct

description: The racemization of peptidyl-alanine.


name: peptidyl-D-alanine racemization via peptidyl-L-serine

description: The dehydration of peptidyl-serine, followed by hydrogenation to produce peptidyl-D-alanine.


peptidyl-threonine racemization

description: The racemization of peptidyl-L-threo-threonine at the alpha-carbon to form D-allo-threonine. This is coupled with the formation of the cross-link 2-(S-L-cysteinyl)-D-allo-threonine.


peptidyl-D-alanine racemization

description: The formation of peptidyl-D-alanine, by either racemization or from peptidyl-L-serine.


peptidyl-isoleucine racemization

description: The racemization of peptidyl-isoleucine.


peptidyl-phenylalanine racemization

description: The racemization of peptidyl-phenylalanine.


peptidyl-L-amino acid racemization

description: The process of conversion of a L-amino acid into its enantiomer, the corresponding D-amino acid.


peptidyl-serine racemization

description: The racemization of peptidyl-serine.


tetradecanoyl-AMP

A fatty acyl-AMP that results from the formal condensation of the phosphoryl group of AMP with the carboxyl group of tetradecanoic (myristic) acid.


clidinium

The ester resulting from formal condensation of benzilic acid and 3-hydroxy-1-methyl-1-azoniabicyclo[2.2.2]octane. It is used, generally as the bromide, for the symptomatic treatment of peptic ulcer disease and also to help relieve abdominal or stomach spasms or cramps due to colicky abdominal pain, diverticulitis, and irritable bowel syndrome.


3,4-dihydroxy-L-argininium residue

An L-arginine residue that is substituted by hydroxy groups at positions 3 and 4; major microspecies at pH 7.3.


2-bromohexadecanoic acid

A bromo fatty acid that is hexadecanoic (palmitic) acid carrying a single bromo substituent at position 2.


A thirteen-membered glucosamine oligosaccharide that consists of the linear trisaccharide beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc to which two alpha-L-Fuc-(1->2)-beta-D-Gal-(1->3)-[alpha-L-Fuc-(1->4)]-beta-D-GlcNAc-(1->2)-alpha-D-Man units are attached at positions 3 and 6 of the mannosyl residue.


Early menarche

description: Occurrence of the first menstrual period in a female before the usual or expected age.


Isolated Premature Menarche

description: Occurrence of the first menstrual period in a girl before the lower limit of the normal age range for the reference population, without other signs of puberty.


irregular menstruation (diagnosis)

description: Deviations from the normal process; e.g. delayed, difficult, profuse, scanty, unusual bleeding, etc.


Hypomenorrhea

description: Decreased menstrual blood flow.


N-(3-oxohexanoyl)homoserine lactone

A N-acyl homoserine lactone that is the monocarboxylic acid amide resulting from the formal condensation of the carboxy group of 3-oxohexanoic acid with the amino group of homoserine lactone.


campomelic dysplasia

description: Campomelic dysplasia is a very rare disorder characterized by a variable association of skeletal abnormalities (bowed and fragile long bones, pelvis and chest abnormalities, eleven rib pairs instead of the usual twelve), and extraskeletal abnormalities (facial dysmorphology, cleft palate, sexual ambiguity or sex reversal in two thirds of the affected boys, and brain, heart and kidney malformations).


name: negative regulation of attachment of mitotic spindle microtubules to kinetochore

description: Any process that stops, prevents or reduces the frequency, rate or extent of attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation.


name: ascospore wall beta-glucan metabolic process

description: The chemical reactions and pathways involving beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of ascospores.


name: ascospore wall (1->3)-beta-D-glucan metabolic process

description: The chemical reactions and pathways involving (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds, found in the walls of ascospores.


name: regulation of cellular component organization

description: Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.


regulation of chromosome organization

description: Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a chromosome.


name: positive regulation of telomere maintenance via recombination

description: Any process that activates or increases the frequency, rate or extent of a recombinational process involved in the maintenance of proper telomeric length.


name: positive regulation of mitotic cohesin dsDNA (leading strand) loading

description: Any process that activates or increases the frequency, rate or extent of mitotic cohesin dsDNA (leading strand) loading.


regulation of cell junction assembly

description: Any process that modulates the frequency, rate or extent of cell junction assembly.


negative regulation of centrosome cycle

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the centrosome cycle.


name: negative regulation of metaphase/anaphase transition of meiosis I

description: Any process that stops, prevents or reduces the frequency, rate or extent of metaphase/anaphase transition of meiosis I.


name: positive regulation of primary cell septum biogenesis

description: Any process that activates or increases the frequency, rate or extent of primary cell septum biogenesis.


regulation of division septum assembly

description: Any process that modulates the frequency, rate or extent of division septum formation. Division septum formation is the assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following cytokinesis.


regulation of chondrocyte hypertrophy

description: Any process that modulates the frequency, rate or extent of chondrocyte hypertrophy.


name: activation of meiosis I spindle assembly checkpoint

description: Any process that starts the inactive process of a meiosis I cell cycle spindle assembly checkpoint.


name: regulation of mitotic actomyosin contractile ring assembly

description: Any process that modulates the frequency, rate or extent of mitotic actomyosin contractile ring assembly.


regulation of organelle organization

description: Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle.


name: negative regulation of maintenance of sister chromatid cohesion

description: Any process that decreases the extent to which the association between sister chromatids of a replicated chromosome is maintained.


name: positive regulation of maintenance of sister chromatid cohesion

description: Any process that increases the extent to which the association between sister chromatids of a replicated chromosome is maintained.


name: regulation of cell growth involved in cardiac muscle cell development

description: Any process that modulates the rate, frequency, or extent of the growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state.


name: regulation of maintenance of mitotic sister chromatid cohesion, centromeric

description: Any process that modulates the frequency, rate or extent of maintenance of mitotic sister chromatid cohesion in the centromeric region.


name: regulation of cytoskeleton polarization involved in growth plate cartilage chondrocyte division

description: The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell that modulates the rate, frequency, or extent of the polarization of cytoskeletal structures in a growth plate cartilage chondrocyte. This process results in the oriented division of the cell.


name: regulation of mitotic chromosome condensation

description: Any process that modulates the frequency, rate or extent of mitotic chromosome condensation.


name: positive regulation of reciprocal meiotic recombination

description: Any process that increases the frequency, rate or extent of recombination during meiosis. Reciprocal meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate.


name: regulation of axon extension involved in axon guidance

description: Any process that modulates the frequency, rate or extent of axon extension involved in axon guidance.


regulation of sister chromatid cohesion

description: Any process that modulates the frequency, rate or extent of sister chromatid cohesion.


name: negative regulation of mitotic sister chromatid arm separation

description: Any process that stops, prevents or reduces the frequency, rate or extent of mitotic sister chromatid arm separation.


name: negative regulation of meiotic spindle elongation

description: Any process that stops, prevents or reduces the frequency, rate or extent of meiotic spindle elongation.


name: negative regulation of centriole replication

description: Any process that stops, prevents, or reduces the frequency, rate or extent of centriole replication.


activation of meiosis

description: Any process that starts the inactive process of meiosis.


name: negative regulation of mitotic nuclear division

description: Any process that stops, prevents or reduces the rate or extent of mitosis. Mitosis is the division of the eukaryotic cell nucleus to produce two daughter nuclei that, usually, contain the identical chromosome complement to their mother.


name: positive regulation of syncytium formation by virus

description: The process in which a virus increases the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells.


name: negative regulation of mitotic division septum assembly

description: Any process that stops, prevents or reduces the frequency, rate or extent of mitotic division septum formation. Division septum formation is the assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following cytokinesis.


termination of bipolar cell growth

description: Any process that stops the active process of bipolar cell growth, polarized growth from both ends of a cell.


name: regulation of mitotic spindle elongation (spindle phase three)

description: Any process that modulates the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the mitotic spindle during mitotic anaphase B (spindle phase three).


regulation of extent of cell growth

description: Any process that modulates the extent of cell growth.


name: positive regulation of telomere maintenance

description: Any process that activates or increases the frequency, rate or extent of a process that affects and monitors the activity of telomeric proteins and the length of telomeric DNA.


name: positive regulation of mitotic spindle organization

description: Any process that activates or increases the frequency, rate or extent of mitotic spindle organization.


name: positive regulation of mitotic spindle disassembly

description: Any process that activates or increases the frequency, rate or extent of mitotic spindle disassembly.


name: regulation of collateral sprouting in absence of injury

description: Any process that modulates the frequency, rate or extent of collateral sprouting in the absence of injury.


name: positive regulation of organelle organization

description: Any process that increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle.


regulation of centriole replication

description: Any process that modulates the frequency, rate or extent of the formation of a daughter centriole of an existing centriole.


name: negative regulation of phospholipid translocation

description: Any process that decreases the frequency, rate or extent of the translocation, or flipping, of phospholipid molecules from one monolayer of a membrane bilayer to the opposite monolayer.


name: negative regulation of centrosome duplication

description: Any process that decreases the frequency, rate or extent of centrosome duplication. Centrosome duplication is the replication of a centrosome, a structure comprised of a pair of centrioles and peri-centriolar material from which a microtubule spindle apparatus is organized.


name: negative regulation of cell septum assembly

description: Any process that stops, prevents or reduces the frequency, rate or extent of cell septum assembly.


name: regulation of cytokinesis, actomyosin contractile ring assembly

description: Any process that modulates the frequency, rate or extent of cytokinesis, actomyosin contractile ring assembly.


name: positive regulation of telomere maintenance via semi-conservative replication

description: Any process that activates or increases the frequency, rate or extent of the semi-conservative replication of telomeric DNA.


name: positive regulation of mitotic cohesin unloading

description: Any process that activates or increases the frequency, rate or extent of mitotic cohesin unloading.


regulation of telomere maintenance

description: Any process that modulates the frequency, rate or extent of a process that affects and monitors the activity of telomeric proteins and the length of telomeric DNA.


name: regulation of phospholipid translocation

description: Any process that modulates the frequency, rate or extent of the translocation, or flipping, of phospholipid molecules from one monolayer of a membrane bilayer to the opposite monolayer.


name: regulation of plasma membrane bounded cell projection organization

description: Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of plasma membrane bounded cell projections.


name: positive regulation of mitochondrial DNA replication

description: Any process that increases the rate, frequency or extent of the process in which new strands of DNA are synthesized in the mitochondrion.


regulation of telomeric loop formation

description: Any process that modulates the frequency, rate or extent of telomeric loop formation.


name: negative regulation of mitotic spindle elongation (spindle phase three)

description: Any process that stops, prevents or reduces the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the mitotic spindle during mitotic anaphase B (spindle phase three).


name: negative regulation of cytokinesis, actomyosin contractile ring assembly

description: Any process that stops, prevents or reduces the frequency, rate or extent of cytokinesis, actomyosin contractile ring assembly.


name: regulation of maintenance of sister chromatid cohesion

description: Any process that modulates the extent to which the association between sister chromatids of a replicated chromosome is maintained.


name: negative regulation of secondary cell septum biogenesis

description: Any process that stops, prevents or reduces the frequency, rate or extent of secondary cell septum biogenesis.


name: positive regulation of protein insertion into mitochondrial outer membrane

description: Any process that activates or increases the frequency, rate or extent of protein insertion into mitochondrial outer membrane.


name: regulation of mitotic cohesin dsDNA (leading strand) loading

description: Any process that modulates the frequency, rate or extent of mitotic cohesin dsDNA (leading strand) loading.


name: regulation of mitotic cohesin ssDNA (lagging strand) loading

description: Any process that modulates the frequency, rate or extent of mitotic cohesin ssDNA (lagging strand) loading.


name: regulation of replication fork arrest at rDNA repeats

description: Any process that modulates the frequency, rate or extent of replication fork arrest at rDNA repeats.


name: positive regulation of maintenance of mitotic sister chromatid cohesion

description: Any process that increases the extent to which the association between sister chromatids of a replicated chromosome is maintained during a mitotic cell cycle.


name: regulation of telomere maintenance via recombination

description: Any process that modulates the frequency, rate or extent of a recombinational process involved in the maintenance of proper telomeric length.


regulation of t-circle formation

description: Any process that modulates the frequency, rate or extent of t-circle formation.


regulation of axon diameter

description: Any process that modulates the rate, direction or extent of axon growth such that the correct diameter is attained and maintained.


name: regulation of telomere maintenance via telomere lengthening

description: Any process that modulates the frequency, rate or extent of telomere maintenance via telomere lengthening.


name: negative regulation of phospholipid scramblase activity

description: Any process that stops, prevents or reduces the frequency, rate or extent of phospholipid scramblase activity.


name: regulation of mitotic nuclear envelope disassembly

description: Any process that modulates the frequency, rate or extent of mitotic nuclear envelope disassembly.


name: regulation of metaphase/anaphase transition of meiosis II

description: Any process that modulates the frequency, rate or extent of metaphase/anaphase transition of meiosis II.


name: positive regulation of phospholipid scramblase activity

description: Any process that activates or increases the frequency, rate or extent of phospholipid scramblase activity.


name: regulation of centromeric sister chromatid cohesion

description: Any process that modulates the frequency, rate or extent of sister chromatid cohesion in the centromeric region of a chromosome.


name: positive regulation of sarcomere organization

description: Any process that increases the rate, frequency or extent of myofibril assembly by organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs.


regulation of meiotic nuclear division

description: Any process that modulates the frequency, rate or extent of meiotic nuclear division, the process in which the nucleus of a diploid cell divides twice forming four haploid cells, one or more of which usually function as gametes.


name: regulation of mitotic metaphase/anaphase transition

description: Any process that modulates the frequency, rate or extent of the cell cycle process in which a cell progresses from metaphase to anaphase during mitosis, triggered by the activation of the anaphase promoting complex by Cdc20/Sleepy homolog which results in the degradation of Securin.


name: negative regulation of death-inducing signaling complex assembly

description: Any process that stops, prevents or reduces the frequency, rate or extent of death-inducing signaling complex assembly.


name: negative regulation of apoptosome assembly

description: Any process that stops, prevents or reduces the frequency, rate or extent of apoptosome assembly.


name: positive regulation of mitotic metaphase/anaphase transition

description: Any process that activates or increases the frequency, rate or extent of the cell cycle process in which a cell progresses from metaphase to anaphase during mitosis, triggered by the activation of the anaphase promoting complex by Cdc20/Sleepy homolog which results in the degradation of Securin.


name: positive regulation of telomere maintenance in response to DNA damage

description: Any process that activates or increases the frequency, rate or extent of telomere maintenance in response to DNA damage.


name: cell growth mode switching, monopolar to bipolar

description: The process in which a cell switches from monopolar cell growth to bipolar cell growth.


name: regulation of mitotic spindle disassembly

description: Any process that modulates the frequency, rate or extent of mitotic spindle disassembly.


name: positive regulation of protection from non-homologous end joining at telomere

description: Any process that activates or increases the frequency, rate or extent of protection from non-homologous end joining at telomere.


name: regulation of ascospore-type prospore membrane formation

description: Any process that modulates the frequency, rate or extent of formation of an ascospore-type prospore membrane.


name: negative regulation of meiotic nuclear division

description: Any process that stops, prevents, or reduces the frequency, rate or extent of meiosis.


name: positive regulation of telomere maintenance via telomere lengthening

description: Any process that activates or increases the frequency, rate or extent of telomere maintenance via telomere lengthening.


regulation of spindle organization

description: Any process that modulates the rate, frequency or extent of the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle.


name: positive regulation of metaphase/anaphase transition of cell cycle

description: Any process that activates or increases the frequency, rate or extent of metaphase/anaphase transition of cell cycle.


name: regulation of sister chromatid segregation

description: Any process that modulates the frequency, rate or extent of sister chromatid segregation.


regulation of pseudohyphal growth

description: Any process that modulates the frequency, rate or extent of pseudohyphal growth.


name: positive regulation of sister chromatid cohesion

description: Any process that activates or increases the frequency, rate or extent of sister chromatid cohesion.


regulation of collateral sprouting

description: Any process that modulates the frequency, rate or extent of collateral sprouting.


name: positive regulation of maintenance of mitotic sister chromatid cohesion, telomeric

description: Any process that activates or increases the frequency, rate or extent of maintenance of mitotic sister chromatid cohesion, telomeric.


negative regulation of nuclear division

description: Any process that stops, prevents, or reduces the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information.


name: positive regulation of mitotic cohesin ssDNA (lagging strand) loading

description: Any process that activates or increases the frequency, rate or extent of mitotic cohesin ssDNA (lagging strand) loading.


name: regulation of mitochondrion organization

description: Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a mitochondrion.


name: activation of reciprocal meiotic recombination

description: Any process that starts the inactive process of reciprocal meiotic recombination. Reciprocal meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate.


name: positive regulation of mitochondrial DNA metabolic process

description: Any process that activates or increases the frequency, rate or extent of mitochondrial DNA metabolic process.


name: negative regulation of astral microtubule depolymerization

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the depolymerization of astral microtubules.


name: regulation of protein-containing complex assembly

description: Any process that modulates the frequency, rate or extent of protein complex assembly.


regulation of bipolar cell growth

description: Any process that modulates the frequency, rate or extent of bipolar cell growth, polarized growth from both ends of a cell.


name: positive regulation of cytokinesis, actomyosin contractile ring assembly

description: Any process that activates or increases the frequency, rate or extent of cytokinesis, actomyosin contractile ring assembly.


positive regulation of spindle assembly

description: Any process that activates or increases the frequency, rate or extent of spindle assembly.


regulation of telomere capping

description: Any process that modulates the frequency, rate or extent of telomere capping.


regulation of dendrite extension

description: Any process that modulates the frequency, rate or extent of dendrite extension.


regulation of meiosis I

description: Any process that modulates the rate, frequency, or extent of meiosis I, a cell cycle process comprising the steps by which a cell progresses through the first phase of meiosis, in which cells divide and homologous chromosomes are paired and segregated from each other, producing two daughter cells.


name: negative regulation of collateral sprouting in absence of injury

description: Any process that stops, prevents, or reduces the frequency, rate or extent of collateral sprouting in the absence of injury.


name: positive regulation of integrin activation by cell surface receptor linked signal transduction

description: Any process that activates or increases the frequency, rate, or extent of integrin activation by cell surface receptor linked signal transduction. This can occur by increased affinity of an integrin for its extracellular ligands.


name: regulation of maintenance of mitotic sister chromatid cohesion, arms

description: Any process that modulates the frequency, rate or extent of maintenance of mitotic sister chromatid cohesion along the chromosome arms.


name: negative regulation of mitotic cohesin loading

description: Any process that stops, prevents or reduces the frequency, rate or extent of mitotic cohesin loading.


name: negative regulation of neuron projection development

description: Any process that decreases the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).


name: negative regulation of cell projection organization

description: Any process that stops, prevents, or reduces the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell projections.


positive regulation of meiosis I

description: Any process that increases the rate, frequency, or extent of meiosis I, a cell cycle process comprising the steps by which a cell progresses through the first phase of meiosis, in which cells divide and homologous chromosomes are paired and segregated from each other, producing two daughter cells.


name: regulation of meiosis I spindle assembly checkpoint

description: Any process that modulates the frequency, rate or extent of the meiosis I spindle assembly checkpoint.


regulation of mitotic spindle assembly

description: Any process that modulates the frequency, rate or extent of mitotic spindle assembly.


name: negative regulation of maintenance of mitotic sister chromatid cohesion

description: Any process that decreases the extent to which the association between sister chromatids of a replicated chromosome is maintained during a mitotic cell cycle.


name: negative regulation of sister chromatid segregation

description: Any process that stops, prevents, or reduces the frequency, rate or extent of sister chromatid segregation.


name: positive regulation of centriole replication

description: Any process that activates or increases the frequency, rate or extent of centriole replication.


name: positive regulation of ascospore-type prospore membrane formation

description: Any process that activates or increases the frequency, rate or extent of formation of an ascospore-type prospore membrane.


regulation of mitotic cohesin unloading

description: Any process that modulates the frequency, rate or extent of mitotic cohesin unloading.


name: negative regulation of bipolar cell growth

description: Any process that stops, prevents, or reduces the frequency, rate or extent of bipolar cell growth, polarized growth from both ends of a cell.


name: negative regulation of mitotic actomyosin contractile ring assembly

description: Any process that stops, prevents or reduces the frequency, rate or extent of mitotic actomyosin contractile ring assembly.


name: negative regulation of oocyte karyosome formation

description: Any process that stops, prevents, or reduces the frequency, rate or extent of oocyte karyosome formation, the chromosome organization process in which meiotic chromosomes in the oocyte nucleus cluster together to form a compact spherical structure called the karyosome.


name: negative regulation of chromosome organization

description: Any process that stops, prevents or reduces the frequency, rate or extent of chromosome organization.


positive regulation of telomere capping

description: Any process that activates or increases the frequency, rate or extent of telomere capping.


name: negative regulation of mitotic cohesin ssDNA (lagging strand) loading

description: Any process that stops, prevents or reduces the frequency, rate or extent of mitotic cohesin ssDNA (lagging strand) loading.


name: negative regulation of dendrite extension

description: Any process that stops, prevents or reduces the frequency, rate or extent of dendrite extension.


name: regulation of cell growth by extracellular stimulus

description: Any process in which external signals modulate the frequency, rate or extent of cell growth, the irreversible increase in size of a cell over time.


name: positive regulation of metaphase/anaphase transition of meiosis I

description: Any process that activates or increases the frequency, rate or extent of metaphase/anaphase transition of meiosis I.


name: regulation of collateral sprouting of injured axon

description: Any process that modulates the frequency, rate or extent of collateral sprouting of an injured axon.


name: negative regulation of primary cell septum biogenesis

description: Any process that stops, prevents or reduces the frequency, rate or extent of primary cell septum biogenesis.


name: regulation of neuron projection development

description: Any process that modulates the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).


name: positive regulation of septation initiation signaling

description: Any process that activates or increases the frequency, rate or extent of septation initiation signaling.


name: regulation of mitotic spindle formation (spindle phase one)

description: Any process that modulates the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the mitotic spindle during mitotic prophase (spindle phase one).


name: positive regulation of cell projection organization

description: Any process that activates or increases the frequency, rate or extent of the process involved in the formation, arrangement of constituent parts, or disassembly of cell projections.


name: negative regulation of chondrocyte hypertrophy

description: Any process that stops, prevents or reduces the frequency, rate or extent of chondrocyte hypertrophy.


regulation of cohesin unloading

description: Any process that modulates the frequency, rate or extent of cohesin unloading.


positive regulation of cohesin loading

description: Any process that activates or increases the frequency, rate or extent of cohesin loading.


regulation of mitotic cohesin loading

description: Any process that modulates the frequency, rate or extent of mitotic cohesin loading.


name: negative regulation of metaphase/anaphase transition of cell cycle

description: Any process that stops, prevents or reduces the frequency, rate or extent of metaphase/anaphase transition of cell cycle.


name: negative regulation of organelle organization

description: Any process that decreases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle.


name: regulation of protection from non-homologous end joining at telomere

description: Any process that modulates the frequency, rate or extent of protection from non-homologous end joining at telomere.


name: negative regulation of pseudohyphal growth

description: Any process that stops, prevents, or reduces the frequency, rate or extent of pseudohyphal growth.


name: positive regulation of phosphatidylserine exposure on apoptotic cell surface

description: Any process that activates or increases the frequency, rate or extent of phosphatidylserine exposure on apoptotic cell surface.


name: regulation of cell projection organization

description: Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell projections.


name: regulation of telomere maintenance via semi-conservative replication

description: Any process that modulates the frequency, rate or extent of the semi-conservative replication of telomeric DNA.


name: positive regulation of maintenance of meiotic sister chromatid cohesion, centromeric

description: Any process that activates or increases the frequency, rate or extent of maintenance of meiotic sister chromatid cohesion in the centromeric region.


name: negative regulation of division septum assembly

description: Any process that decreases the frequency, rate or extent of division septum formation. division septum formation is he assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following cytokinesis.


name: negative regulation of maintenance of mitotic sister chromatid cohesion, centromeric

description: Any process that stops, prevents or reduces the frequency, rate or extent of maintenance of mitotic sister chromatid cohesion in the centromeric region.


name: positive regulation of t-circle formation

description: Any process that activates or increases the frequency, rate or extent of t-circle formation.


name: positive regulation of metaphase/anaphase transition of meiosis II

description: Any process that activates or increases the frequency, rate or extent of metaphase/anaphase transition of meiosis II.


name: negative regulation of mitotic spindle formation (spindle phase one)

description: Any process that stops, prevents or reduces the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the mitotic spindle during mitotic prophase (spindle phase one).


name: positive regulation of telomeric loop formation

description: Any process that activates or increases the frequency, rate or extent of telomeric loop formation.


regulation of cytoskeleton organization

description: Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures.


name: positive regulation of mitotic nuclear division

description: Any process that activates or increases the frequency, rate or extent of mitosis.


name: negative regulation of release of cytochrome c from mitochondria

description: Any process that decreases the rate, frequency or extent of release of cytochrome c from mitochondria, the process in which cytochrome c is enabled to move from the mitochondrial intermembrane space into the cytosol, which is an early step in apoptosis and leads to caspase activation.


name: regulation of oocyte karyosome formation

description: Any process that modulates the frequency, rate or extent of oocyte karyosome formation, the chromosome organization process in which meiotic chromosomes in the oocyte nucleus cluster together to form a compact spherical structure called the karyosome.


name: negative regulation of mitotic nuclear envelope disassembly

description: Any process that stops, prevents or reduces the frequency, rate or extent of mitotic nuclear envelope disassembly.


name: regulation of lateral attachment of mitotic spindle microtubules to kinetochore

description: Any process that modulates the frequency, rate or extent of lateral attachment of mitotic spindle microtubules to kinetochore.


name: positive regulation of synaptonemal complex assembly

description: Any process that activates or increases the frequency, rate or extent of synaptonemal complex assembly.


name: cell growth mode switching, bipolar to monopolar

description: The process in which a cell switches from bipolar cell growth to monopolar cell growth.


name: positive regulation of mitotic cell cycle spindle assembly checkpoint

description: Any process that increases the rate, frequency, or extent of the mitotic cell cycle spindle assembly checkpoint, a cell cycle checkpoint that delays the metaphase/anaphase transition of a mitotic nuclear division until the spindle is correctly assembled and chromosomes are attached to the spindle.


name: negative regulation of maintenance of mitotic sister chromatid cohesion, arms

description: Any process that stops, prevents or reduces the frequency, rate or extent of maintenance of mitotic sister chromatid cohesion along the chromosome arms.


termination of monopolar cell growth

description: Any process that stops the active process of bipolar cell growth, polarized growth from one end of a cell.


name: positive regulation of centriole elongation

description: Any process that activates or increases the frequency, rate or extent of centriole elongation.


name: negative regulation of cellular component organization

description: Any process that stops, prevents, or reduces the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.


name: positive regulation of cohesin unloading

description: Any process that activates or increases the frequency, rate or extent of cohesin unloading.


regulation of root hair elongation

description: Any process that modulates the frequency, rate or extent of root hair elongation.


name: regulation of primary cell septum biogenesis

description: Any process that modulates the frequency, rate or extent of primary cell septum biogenesis.


name: positive regulation of oocyte karyosome formation

description: Any process that activates or increases the frequency, rate or extent of oocyte karyosome formation, the chromosome organization process in which meiotic chromosomes in the oocyte nucleus cluster together to form a compact spherical structure called the karyosome.


name: negative regulation of cohesin unloading

description: Any process that stops, prevents or reduces the frequency, rate or extent of cohesin unloading.


name: regulation of phosphatidylserine exposure on apoptotic cell surface

description: Any process that modulates the frequency, rate or extent of phosphatidylserine exposure on apoptotic cell surface.


name: positive regulation of mitotic division septum assembly

description: Any process that activates or increases the frequency, rate or extent of mitotic division septum formation. Division septum formation is the assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following cytokinesis.


name: positive regulation of synapse maturation by synaptic transmission

description: Any process that increases the extent of synaptic maturation as a result of the communication from a pre-synaptic cell to a post-synaptic cell across a synapse.


regulation of mitotic nuclear division

description: Any process that modulates the frequency, rate or extent of mitosis.


regulation of sprouting of injured axon

description: Any process that modulates the frequency, rate or extent of sprouting of an injured axon.


name: negative regulation of unidimensional cell growth

description: Any process that stops, prevents, or reduces the frequency, rate or extent of unidimensional cell growth, the process in which a cell irreversibly increases in size in one [spatial] dimension or along one axis.


name: positive regulation of mitotic actomyosin contractile ring assembly

description: Any process that activates or increases the frequency, rate or extent of mitotic actomyosin contractile ring assembly.


name: negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway

description: Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway.


name: regulation of formation of growth cone in injured axon

description: Any process that modulates the frequency, rate or extent of formation of growth cone in injured axon.


name: regulation of mitotic division septum assembly

description: Any process that modulates the frequency, rate or extent of mitotic division septum formation. Division septum formation is the assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following cytokinesis.


mitotic cohesin unloading

description: Negative regulation of sister chromatid cohesion by the topological unlinking of a cohesin ring to DNA as part of the mitotic cell cycle.


regulation of linear element assembly

description: Any process that modulates the rate, frequency or extent of linear element assembly. Linear element assembly is the cell cycle process in which a proteinaceous scaffold, related to the synaptonemal complex, is assembled in association with S. pombe chromosomes during meiotic prophase.


name: negative regulation of monopolar cell growth

description: Any process that stops, prevents, or reduces the frequency, rate or extent of monopolar cell growth, polarized growth from one end of a cell.


name: positive regulation of maintenance of mitotic sister chromatid cohesion, arms

description: Any process that activates or increases the frequency, rate or extent of maintenance of mitotic sister chromatid cohesion along the chromosome arms.


negative regulation of cohesin loading

description: Any process that stops, prevents, or reduces the frequency, rate or extent of a process in which a cohesin complex is transported to, or maintained at, a part of a chromosome that is organized into chromatin.


name: negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric

description: Any process that stops, prevents or reduces the frequency, rate or extent of maintenance of mitotic sister chromatid cohesion, telomeric.


name: positive regulation of metaphase/anaphase transition of meiotic cell cycle

description: Any process that activates or increases the frequency, rate or extent of metaphase/anaphase transition of meiotic cell cycle.


name: negative regulation of metaphase/anaphase transition of meiosis II

description: Any process that stops, prevents or reduces the frequency, rate or extent of metaphase/anaphase transition of meiosis II.


name: negative regulation of axon extension involved in axon guidance

description: Any process that stops, prevents, or reduces the frequency, rate or extent of axon extension involved in axon guidance.


name: negative regulation of mitotic sister chromatid segregation

description: Any process that stops, prevents, or reduces the frequency, rate or extent of sister chromatid segregation during mitosis.


name: positive regulation of protein-containing complex assembly

description: Any process that activates or increases the frequency, rate or extent of protein complex assembly.


name: positive regulation of attachment of mitotic spindle microtubules to kinetochore

description: Any process that activates or increases the frequency, rate or extent of attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation.


name: positive regulation of division septum assembly

description: Any process that increases the frequency, rate or extent of division septum formation. division septum formation is the assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following cytokinesis.


name: positive regulation of bicellular tight junction assembly

description: Any process that activates or increases the frequency, rate or extent of tight junction assembly.


name: positive regulation of cellular component organization

description: Any process that activates or increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.


name: negative regulation of direction of cell growth

description: Any process that decreases the direction of cell growth.


name: negative regulation of sister chromatid cohesion

description: Any process that stops, prevents, or reduces the frequency, rate or extent of sister chromatid cohesion.


name: regulation of maintenance of meiotic sister chromatid cohesion, centromeric

description: Any process that modulates the frequency, rate or extent of maintenance of meiotic sister chromatid cohesion in the centromeric region.


name: negative regulation of mitotic cohesin dsDNA (leading strand) loading

description: Any process that stops, prevents or reduces the frequency, rate or extent of mitotic cohesin dsDNA (leading strand) loading.


regulation of cell septum assembly

description: Any process that modulates the frequency, rate or extent of cell septum assembly.


name: positive regulation of mitotic cohesin loading

description: Any process that activates or increases the frequency, rate or extent of mitotic cohesin loading.


name: regulation of metaphase/anaphase transition of meiosis I

description: Any process that modulates the frequency, rate or extent of metaphase/anaphase transition of meiosis I.


regulation of direction of cell growth

description: Any process that modulates the direction of cell growth.


name: negative regulation of septation initiation signaling

description: Any process that stops, prevents, or reduces the frequency, rate or extent of septation initiation signaling.


positive regulation of centrosome cycle

description: Any process that activates or increases the frequency, rate or extent of the centrosome cycle.


name: positive regulation of mitotic spindle formation (spindle phase one)

description: Any process that activates or increases the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the mitotic spindle during mitotic prophase (spindle phase one).


cohesin unloading

description: Negative regulation of sister chromatid cohesion by the topological unlinking of a cohesin ring to DNA.


regulation of linear element maturation

description: Any process that modulates the rate, frequency or extent of linear element maturation.


name: positive regulation of mitotic chromosome condensation

description: Any process that activates or increases the frequency, rate or extent of mitotic chromosome condensation.


name: negative regulation of bicellular tight junction assembly

description: Any process that stops, prevents or reduces the frequency, rate or extent of tight junction assembly.


name: regulation of maintenance of mitotic sister chromatid cohesion, telomeric

description: Any process that modulates the frequency, rate or extent of maintenance of mitotic sister chromatid cohesion, telomeric.


name: regulation of metaphase/anaphase transition of cell cycle

description: Any process that modulates the frequency, rate or extent of metaphase/anaphase transition of cell cycle.


name: positive regulation of secondary cell septum biogenesis

description: Any process that activates or increases the frequency, rate or extent of secondary cell septum biogenesis.


name: negative regulation of maintenance of meiotic sister chromatid cohesion, centromeric

description: Any process that stops, prevents or reduces the frequency, rate or extent of maintenance of meiotic sister chromatid cohesion in the centromeric region.


regulation of centrosome duplication

description: Any process that modulates the frequency, rate or extent of centrosome duplication. Centrosome duplication is the replication of a centrosome, a structure comprised of a pair of centrioles and peri-centriolar material from which a microtubule spindle apparatus is organized.


negative regulation of spindle assembly

description: Any process that stops, prevents or reduces the frequency, rate or extent of spindle assembly.


name: activation of mitotic cell cycle spindle assembly checkpoint

description: Any process that starts the inactive process of a mitotic cell cycle spindle assembly checkpoint.


name: negative regulation of mitotic chromosome condensation

description: Any process that stops, prevents or reduces the frequency, rate or extent of mitotic chromosome condensation.


regulation of axon extension

description: Any process that modulates the rate, direction or extent of axon extension.


name: positive regulation of maintenance of mitotic sister chromatid cohesion, centromeric

description: Any process that activates or increases the frequency, rate or extent of maintenance of mitotic sister chromatid cohesion in the centromeric region.


name: negative regulation of mitotic sister chromatid separation

description: Any process that stops, prevents or reduces the frequency, rate or extent of mitotic sister chromatid separation.


name: regulation of maintenance of mitotic sister chromatid cohesion

description: Any process that modulates the extent to which the association between sister chromatids of a replicated chromosome is maintained during a mitotic cell cycle.


name: regulation of telomere maintenance in response to DNA damage

description: Any process that modulates the frequency, rate or extent of telomere maintenance in response to DNA damage.


name: positive regulation of meiotic nuclear division

description: Any process that activates or increases the frequency, rate or extent of meiosis.


name: regulation of unidimensional cell growth

description: Any process that modulates the frequency, rate or extent of unidimensional cell growth, the process in which a cell irreversibly increases in size in one [spatial] dimension or along one axis.


name: negative regulation of cell growth involved in contact inhibition

description: The negative regulation of cell growth in response to increased cell density.


name: regulation of microtubule cytoskeleton organization

description: Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins.


name: negative regulation of maintenance of meiotic sister chromatid cohesion

description: Any process that decreases the extent to which the association between sister chromatids of a replicated chromosome is maintained during a meiotic cell cycle.


name: regulation of attachment of mitotic spindle microtubules to kinetochore

description: Any process that modulates the frequency, rate or extent of attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation.


name: regulation of synaptonemal complex assembly

description: Any process that modulates the frequency, rate or extent of synaptonemal complex assembly. Synaptonemal complex assembly is the cell cycle process in which the synaptonemal complex, a structure that holds paired chromosomes together during prophase I of meiosis and that promotes genetic recombination, is formed.


name: regulation of maintenance of meiotic sister chromatid cohesion

description: Any process that modulates the extent to which the association between sister chromatids of a replicated chromosome is maintained during a meiotic cell cycle.


name: Wnt signaling pathway, regulating spindle positioning

description: The series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell and ending with the positioning of the mitotic spindle.


name: positive regulation of cell septum assembly

description: Any process that activates or increases the frequency, rate or extent of cell septum assembly.


name: positive regulation of centrosome duplication

description: Any process that increases the frequency, rate or extent of centrosome duplication. Centrosome duplication is the replication of a centrosome, a structure comprised of a pair of centrioles and peri-centriolar material from which a microtubule spindle apparatus is organized.


name: regulation of axon extension involved in regeneration

description: Any process that modulates the frequency, rate or extent of axon extension involved in regeneration.


name: negative regulation of mitotic metaphase/anaphase transition

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the cell cycle process in which a cell progresses from metaphase to anaphase during mitosis, triggered by the activation of the anaphase promoting complex by Cdc20/Sleepy homolog which results in the degradation of Securin.


negative regulation of meiosis I

description: Any process that stops, prevents, or reduces the frequency, rate or extent of meiosis I, a cell cycle process comprising the steps by which a cell progresses through the first phase of meiosis, in which cells divide and homologous chromosomes are paired and segregated from each other, producing two daughter cells.


name: positive regulation of meiosis I spindle assembly checkpoint

description: Any process that activates or increases the frequency, rate or extent of the meiosis I spindle assembly checkpoint.


negative regulation of axon extension

description: Any process that stops, prevents, or reduces the frequency, rate or extent of axon outgrowth.


name: negative regulation of cell growth involved in cardiac muscle cell development

description: Any process that decreases the rate, frequency, or extent of the growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state.


regulation of cohesin loading

description: Any process that modulates the frequency, rate or extent of a process in which a cohesin complex is transported to, or maintained at, a part of a chromosome that is organized into chromatin.


name: negative regulation of metaphase/anaphase transition of meiotic cell cycle

description: Any process that stops, prevents or reduces the frequency, rate or extent of metaphase/anaphase transition of meiotic cell cycle.


name: regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway

description: Any process that modulates the frequency, rate or extent of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway.


name: activation of meiosis involved in egg activation

description: Any process that starts the inactive process of meiosis in an egg after the egg has been fertilized or physiologically activated. Eggs generally arrest in meiosis and complete the process after activation.


regulation of monopolar cell growth

description: Any process that modulates the frequency, rate or extent of monopolar cell growth, polarized growth from one end of a cell.


name: negative regulation of phosphatidylserine exposure on apoptotic cell surface

description: Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidylserine exposure on apoptotic cell surface.


name: regulation of metaphase/anaphase transition of meiotic cell cycle

description: Any process that modulates the frequency, rate or extent of metaphase/anaphase transition of meiotic cell cycle.


regulation of nuclear division

description: Any process that modulates the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information.


name: regulation of mitotic sister chromatid segregation

description: Any process that modulates the frequency, rate or extent of sister chromatid segregation during mitosis.


name: positive regulation of maintenance of meiotic sister chromatid cohesion

description: Any process that increases the extent to which the association between sister chromatids of a replicated chromosome is maintained during a meiotic cell cycle.


regulation of rate of cell growth

description: Any process that modulates the rate of cell growth.


name: negative regulation of collateral sprouting

description: Any process that stops, prevents, or reduces the frequency, rate or extent of collateral sprouting.


regulation of pollen tube growth

description: Any process that modulates the frequency, rate or extent of pollen tube growth.


name: regulation of mitotic cell cycle spindle assembly checkpoint

description: Any process that modulates the rate, frequency, or extent of the mitotic cell cycle spindle assembly checkpoint, a cell cycle checkpoint that delays the metaphase/anaphase transition of a mitotic nuclear division until the spindle is correctly assembled and chromosomes are attached to the spindle.


name: positive regulation of phospholipid translocation

description: Any process that increases the frequency, rate or extent of the translocation, or flipping, of phospholipid molecules from one monolayer of a membrane bilayer to the opposite monolayer.


regulation of centrosome cycle

description: Any process that modulates the frequency, rate or extent of the centrosome cycle, the processes of centrosome duplication and separation.


name: regulation of phospholipid scramblase activity

description: Any process that modulates the frequency, rate or extent of phospholipid scramblase activity.


regulation of spindle assembly

description: Any process that modulates the rate, frequency or extent of spindle assembly. Spindle assembly is the aggregation, arrangement and bonding together of a set of components to form the spindle, the array of microtubules and associated molecules that serves to move duplicated chromosomes apart.


polyimide macromolecule

A macromolecule composed of units connected by dicarboximide (-C(=O)-NR-C(=O)-) linkages, where R can be H or organyl.


regulation of protein localization

description: Any process that modulates the frequency, rate or extent of any process in which a protein is transported to, or maintained in, a specific location.


name: positive regulation of protein localization

description: Any process that activates or increases the frequency, rate or extent of a protein localization.