name: bacterial cellulose biosynthetic process

description: The chemical reactions and pathways resulting in the formation of cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation, as it occurs in certain types of bacteria, mainly Acetobacter, Sarcina ventriculi and Agrobacteria.


name: regulation of DNA recombination at centromere

category: biolink:BiologicalProcess biolink:Occurrent biolink:OntologyClass biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: Any process that modulates the frequency, rate or extent of DNA recombination within centromeric DNA.


category: biolink:MolecularActivity biolink:Occurrent biolink:OntologyClass biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: Combining with the sphingolipid sphingosine-1-phosphate (S1P), and transmitting the signal across the membrane by activating an associated G-protein.


name: gibberellic acid mediated signaling pathway

category: biolink:Pathway biolink:OntologyClass biolink:BiologicalProcess biolink:Occurrent biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: The series of molecular signals mediated by the detection of gibberellic acid.


mRNA binding

description: Binding to messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.


protein carbamoylation

description: The addition of a carbamoyl group to a protein amino acid. A carbamoyl group is the acyl group -CO-NH2.


ATP-dependent activity, acting on RNA

description: Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction requires the presence of RNA, and it drives another reaction.


ureteric peristalsis

description: A wavelike sequence of involuntary muscular contraction and relaxation that passes along the ureter, impelling the contents onwards. The ureter is one of a pair of thick-walled tubes that transports urine from the kidney pelvis to the urinary bladder.


name: negative regulation of monocyte differentiation

description: Any process that stops, prevents, or reduces the frequency, rate or extent of monocyte differentiation.


name: dihydroneopterin triphosphate pyrophosphohydrolase activity

description: Catalysis of the reaction: dihydroneopterin triphosphate = dihydroneopterin phosphate + diphosphate.


macrophage apoptotic process

description: Any apoptotic process in a macrophage, a mononuclear phagocyte present in a variety of tissues.


chloroplast rRNA processing

description: Any rRNA processing that takes place in chloroplast.


name: maintenance of transcriptional fidelity during transcription elongation by RNA polymerase III

description: Suppression of the occurrence of transcriptional errors, such as substitutions and/or insertions of nucleotides that do not correctly match the template base, during the process of transcription elongation from a RNA polymerase III promoter.


thiazole metabolic process

description: The chemical reactions and pathways involving thiazole, a five-membered heterocyclic ring structure containing a sulfur in the 1-position and a nitrogen in the 3-position.


formate metabolic process

description: The chemical reactions and pathways involving formate, also known as methanoate, the anion HCOO- derived from methanoic (formic) acid.


name: negative regulation of adaptive immune effector response

description: Any process that stops, prevents or reduces the frequency, rate or extent of adaptive immune effector response.


name: negative regulation of spindle checkpoint

description: Any process that decreases the rate, frequency, or extent of the spindle checkpoint, a cell cycle checkpoint that delays the metaphase/anaphase transition until the spindle is correctly assembled and oriented, and chromosomes are attached to the spindle.


name: positive regulation of biological process

description: Any process that activates or increases the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.


name: negative regulation of phosphatidylethanolamine metabolic process

description: Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidylethanolamine metabolic process.


termination of signal transduction

description: The signaling process in which signal transduction is brought to an end rather than being reversibly modulated.


name: ceramide phosphoethanolamine catabolic process

description: The chemical reactions and pathways resulting in the breakdown of ceramide phosphoethanolamine.


neutrophil dispersal

description: The movement of a neutrophil away from the site of wound or infection following its initial migration to the site.


localization within membrane

description: Any process in which a substance or cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in, a specific location within a membrane.


name: regulation of DNA-templated DNA replication initiation

description: Any process that modulates the frequency, rate or extent of initiation of DNA-dependent DNA replication; the process in which DNA becomes competent to replicate. In eukaryotes, replication competence is established in early G1 and lost during the ensuing S phase.


name: regulation of memory T cell differentiation

description: Any process that modulates the frequency, rate, or extent of memory T cell differentiation.


name: protein maturation by nickel ion transfer

description: A process that contributes to the delivery of nickel ions to a target protein to facilitate its maturation.


name: viral replication complex formation and maintenance

description: The process of organizing and assembling viral replication proteins in preparation for viral replication.


calcium ion sequestering activity

description: Binding to a calcium ion to prevent it from interacting with other partners or to inhibit its localization to the area of the cell or complex where it is active.


name: low-density lipoprotein particle disassembly

description: The disaggregation of a low-density lipoprotein particle into its constituent components.


name: negative regulation of adenosine receptor signaling pathway

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the adenosine receptor signaling pathway. The adenosine receptor pathway is the series of molecular signals generated as a consequence of an adenosine receptor binding to one of its physiological ligands.


name: RNA polymerase II C-terminal domain O-GlcNAc transferase activity

description: Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + RNA polymerase II large subunit CTD heptapeptide repeat (YSPTSPS) = UDP + RNA polymerase II large subunit CTD heptapeptide repeat 3-O-(N-acetyl-D-glucosaminyl)-L-serine.


name: 16S rRNA (guanine(1516)-N(2))-methyltransferase activity

description: Catalysis of the reaction: S-adenosyl-L-methionine + guanosine(1516) in 16S rRNA = N(2)-methylguanosine(1516) in 16S rRNA + S-adenosyl-L-homocysteine.


name: D-glucose transmembrane transporter activity

description: Enables the transfer of the D-enantiomer of the hexose monosaccharide glucose from one side of a membrane to the other.


small molecule catabolic process

description: The chemical reactions and pathways resulting in the breakdown of small molecules, any low molecular weight, monomeric, non-encoded molecule.


name: regulation of interleukin-18-mediated signaling pathway

description: Any process that modulates the frequency, rate or extent of interleukin-18-mediated signaling pathway.


camalexin biosynthetic process

description: The chemical reactions and pathways resulting in the formation of camalexin, an indole phytoalexin.


plasma membrane raft localization

description: Any process in which plasma membrane rafts are transported to, or maintained in, a specific location.


dAMP metabolic process

description: The chemical reactions and pathways involving dAMP, deoxyadenosine monophosphate (2'-deoxyadenosine 5'-phosphate).


neutrophil differentiation

description: The process in which a myeloid precursor cell acquires the specialized features of a neutrophil.


description: Catalysis of the reaction: 1,2-diacyl-sn-glycerol + UDP-D-galactose = 1,2-diacyl-3-beta-D-galactosyl-sn-glycerol + H+ + UDP.


protein sulfation

description: The addition of a sulfate group as an ester to a protein amino acid.


name: positive regulation of T cell receptor signaling pathway

description: Any process that activates or increases the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a T cell.


tube formation

description: Creation of the central hole of a tube in an anatomical structure through which gases and/or liquids flow.


synaptic transmission, serotonergic

description: The vesicular release of serotonin from a presynapse, across a chemical synapse, the subsequent activation of serotonin receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse.


angiotensin-activated signaling pathway

description: A G protein-coupled receptor signaling pathway initiated by angiotensin II binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.


name: positive regulation of methanofuran biosynthetic process

description: Any process that activates or increases the frequency, rate or extent of methanofuran biosynthetic process.


cellular response to beta-carotene

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a beta-carotene stimulus.


oscillatory cAMP signaling

description: Fluctuation in the extracellular cAMP levels due to the alternate activation of adenylate cyclase, which produces cAMP, and phosphodiesterase, which degrades it. Occurs in Dictyostelium during early sorocarp development. Oscillation in signaling result is directional chemotaxis of cells towards the center of the aggregate.


RNA guanosine-uridine insertion

description: The modification of an RNA molecule by insertion of an guanosine-uridine insertion dinucleotide.


phytoalexin metabolic process

description: The chemical reactions and pathways involving phytoalexins, any of a range of substances produced by plants as part of their defense response.


lipoxin B4 metabolic process

description: The chemical reactions and pathways involving lipoxin B4. Lipoxin B4 is a C20 hydroxy fatty acid having (5S)-, (14R)- and (15S)-hydroxy groups as well as (6E)- (8Z)-, (10E)- and (12E)-double bonds.


name: positive regulation of compound eye retinal cell apoptotic process

description: Any process that activates or increases the frequency, rate or extent of compound eye retinal cell apoptotic process.


secondary piRNA processing

description: A process leading to the generation of a functional secondary piRNA, involving a self-perpetuating piRNA loop, often called the ping-pong cycle, in which piRNAs are amplified by pairing with complementary transcripts (for example the transposable element mRNA target). In Drosophila, the processing involves the piwi proteins aubergine and Argonaute 3 and in mice, the piwi proteins Piwil2 and Piwil4.


isoprenoid catabolic process

description: The chemical reactions and pathways resulting in the breakdown of an isoprenoid compound, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues.


name: proteolysis associated with antigen processing and presentation

description: The hydrolysis of a peptide bond or bonds within a protein contributing to antigen processing and presentation.


cichorine biosynthetic process

description: The chemical reactions and pathways resulting in the formation of cichorine, a secondary metabolite found in some species of fungi.


RNA (guanine-N7)-methylation

description: The addition of a methyl group to the N7 atom in the base portion of a guanine nucleotide residue in an RNA molecule.


name: regulation of transforming growth factor beta receptor signaling pathway

description: Any process that modulates the frequency, rate or extent of activity of any TGF-beta receptor signaling pathway.


description: Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + beta-D-galactosyl-(1->3)-N-acetyl-D-galactosaminyl-R = UDP + beta-D-galactosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->6)]-N-acetyl-D-galactosaminyl-R.


name: indole-containing compound biosynthetic process

description: The chemical reactions and pathways resulting in the formation of compounds that contain an indole (2,3-benzopyrrole) skeleton.


name: regulation of plant-type cell wall cellulose catabolic process

description: Any process that modulates the frequency, rate or extent of plant-type cell wall cellulose catabolic process.


name: high-affinity fructose transmembrane transporter activity

description: Enables the transfer of fructose from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.


orcinol metabolic process

description: The chemical reactions and pathways involving orcinol (5-methyl-1,3-benzenediol), an aromatic compound derived from the fermentation of lichen, and synthesized, probably as a fungicide, by some higher plants.


aflatoxin biosynthetic process

description: The chemical reactions and pathways resulting in the formation of aflatoxin, a fungal metabolite found as a contaminant in moldy grains that induces liver cancer. Aflatoxin induces a G to T transversion at codon 249 of p53, leading to its inactivation. Aflatoxin is converted to a chemical carcinogen by P450.


protein deglutathionylation

description: The protein modification process in which a glutathione molecule is removed from a protein amino acid by breaking a disulfide linkage.


name: pentacyclic triterpenoid catabolic process

description: The chemical reactions and pathways resulting in the breakdown of pentacyclic triterpenoid compounds, terpenoids with six isoprene units and 5 carbon rings.


L-lysine catabolic process to acetate

description: The chemical reactions and pathways resulting in the breakdown of L-lysine into other compounds, including acetate.


name: peptidyl-S-geranylgeranyl-L-cysteine biosynthetic process from peptidyl-cysteine

description: The modification of peptidyl-cysteine to form peptidyl-S-geranylgeranylcysteine; formation of S-geranylgeranyl-L-cysteine may be coupled with subsequent cleavage of a carboxy-terminal tripeptide for the CAAX motif and methyl esterification of the geranylgeranylated cysteine; methyl esterification but not cleavage occurs for the CXC motif. For the type II geranylgeranyltransferase the residue may be found at the first and final positions in the sequence motif C-X-C* or at the final position in the sequence motif C-C*. These motifs are necessary but not sufficient for modification.


description: The chemical reactions and pathways involving any 1,2-diacyl-sn-glycero-3-phosphocholine, the compounds most commonly designated lecithin.


name: snRNA transcription by RNA polymerase III

description: The synthesis of small nuclear RNA (snRNA) from a DNA template by RNA Polymerase III (Pol III), originating at a Pol III promoter.


name: symbiont-mediated evasion of recognition by host complement

description: A process by which a symbiont avoids the effects of recognition by host  complement by altering molecules on the symbiont surface. The host is defined as the larger of the organisms involved in a symbiotic interaction.


name: molybdenum incorporation via L-selenocysteinyl molybdenum bis(molybdopterin guanine dinucleotide)

description: The incorporation of molybdenum into a protein via L-selenocysteinyl molybdenum bis(molybdopterin guanine dinucleotide).


dUDP metabolic process

description: The chemical reactions and pathways involving dUDP, deoxyuridine (5'-)diphosphate.


name: G protein-coupled glutamate receptor signaling pathway

description: A G protein-coupled receptor signaling pathway initiated by glutamate binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process.


name: DNA repair-dependent chromatin remodeling

description: A chromatin remodeling process that allows DNA repair enzyme to access genomic DNA and repair DNA lesions.


ectoderm and mesoderm interaction

description: A cell-cell signaling process occurring between the two gastrulation-generated layers of the ectoderm and the mesoderm.


monoatomic ion homeostasis

description: Any process involved in the maintenance of an internal steady state of monoatomic ions within an organism or cell. Monatomic ions (also called simple ions) are ions consisting of exactly one atom.


dermatan sulfate metabolic process

description: The chemical reactions and pathways involving dermatan sulfate, any of a group of glycosaminoglycans with repeats consisting of beta-(1,4)-linked L-iduronyl-beta-(1,3)-N-acetyl-D-galactosamine 4-sulfate units. They are important components of ground substance or intercellular cement of skin and some connective tissues.


deoxycytidine metabolic process

description: The chemical reactions and pathways involving deoxycytidine, 2-deoxyribosylcytosine, one of the four major nucleosides of DNA.


IDP phosphatase activity

description: Catalysis of the reaction: IDP + H2O = IMP + H+ + phosphate.


name: regulation of rhamnose catabolic process

description: Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of rhamnose, the hexose 6-deoxy-L-mannose.


name: regulation of wound healing, spreading of epidermal cells

description: Any process that modulates the frequency, rate or extent of wound healing, spreading of epidermal cells.


name: sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin)

description: The pathway by which inorganic sulfate is processed and incorporated into sulfated compounds, where the phosphoadenylyl sulfate reduction step is catalyzed by the enzyme phosphoadenylyl-sulfate reductase (thioredoxin) (EC:1.8.4.8).


name: endothelial cell chemotaxis to fibroblast growth factor

description: The directed movement of an endothelial cell in response to the presence of fibroblast growth factor (FGF).


box C/D sno(s)RNA 3'-end processing

description: Any process involved in forming the mature 3' end of a box C/D RNA molecule.


name: negative regulation of cell motility involved in cerebral cortex radial glia guided migration

description: The intracellular signaling pathway that results in the cessation of cell movement involved in lamination of the cerebral cortex.


name: green leaf volatile biosynthetic process

description: The chemical reactions and pathways resulting in the formation of volatile molecules emitted from green plants, such as hexenal, hexenol and hexenyl acetate, from linoleic acid or linolenic acid.


2-methylguanosine metabolic process

description: The chemical reactions and pathways involving 2-methylguanosine.


name: apoptotic process involved in mammary gland involution

description: Any apoptotic process that triggers the activity of proteolytic caspases whose actions dismantle the mammary epithelial cells resulting in their programmed cell death.


name: Notch signaling pathway involved in arterial endothelial cell fate commitment

description: The series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell and contributing to the commitment of a cell to an arterial endothelial cell fate.


name: molybdenum incorporation via L-cysteinyl molybdopterin

description: The incorporation of molybdenum into a protein via L-cysteinyl molybdopterin.


name: establishment of protein localization to plasma membrane

description: The directed movement of a protein to a specific location in a plasma membrane.


beta-1,3-galactosyltransferase activity

description: Catalysis of the transfer of a galactose residue from a donor molecule to an oligosaccharide, forming a beta-1,3-linkage.


description: Catalysis of the reaction: acetyl-CoA + peptide = CoA + N-alpha-acetylpeptide. This reaction is the acetylation of the N-terminal amino acid residue of a peptide or protein.


anaerobic respiration

description: The enzymatic release of energy from inorganic and organic compounds (especially carbohydrates and fats) which uses compounds other than oxygen (e.g. nitrate, sulfate) as the terminal electron acceptor.


name: isopentenyl diphosphate biosynthetic process

description: The chemical reactions and pathways resulting in the formation of isopentenyl diphosphate, an isomer of dimethylallyl diphosphate and the key precursor of all isoprenoids.


name: cotranslational protein targeting to membrane

description: The targeting of proteins to a membrane that occurs during translation. The transport of most secretory proteins, particularly those with more than 100 amino acids, into the endoplasmic reticulum lumen occurs in this manner, as does the import of some proteins into mitochondria.


reproductive process

description: A biological process that directly contributes to the process of producing new individuals by one or two organisms. The new individuals inherit some proportion of their genetic material from the parent or parents.


name: lysine biosynthetic process via diaminopimelate, dehydrogenase pathway

description: The chemical reactions and pathways resulting in the formation of lysine, via the intermediate diaminopimelate; in this pathway tetrahydrodipicolinate is converted to meso-diaminopimelate in a single enzymatic step.


name: voltage-gated sodium channel activity involved in cardiac muscle cell action potential

description: Enables the transmembrane transfer of a sodium ion by a voltage-gated channel through the plasma membrane of a cardiac muscle cell contributing to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.


fibroblast chemotaxis

description: The directed movement of a fibroblast guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).


name: positive regulation of leukocyte cell-cell adhesion

description: Any process that activates or increases the frequency, rate or extent of leukocyte cell-cell adhesion.


name: G protein-coupled purinergic nucleotide receptor activity

description: Combining with a purine nucleotide and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.


tRNA wobble base modification

description: The process in which the nucleotide at position 34 in the anticodon of a tRNA is post-transcriptionally modified.


L-kynurenine catabolic process

description: The chemical reactions and pathways resulting in the breakdown of L-kynurenine, the L-enantiomer of the amino acid kynurenine (3-(2-aminobenzoyl)-alanine).


name: oleate transmembrane transporter activity

description: Enables the transfer of oleate from one side of a membrane to the other.


name: positive regulation of lactation by mesenchymal-epithelial cell signaling

description: The process that increases the rate, frequency, or extent of lactation as a result of the secretion of a signal from the mammary fat and its reception by a mammary epithelial cell.


name: positive regulation of SREBP signaling pathway in response to decreased oxygen levels

description: Any process that activates or increases the frequency, rate or extent of the SREBP signaling pathway in response to a decrease in oxygen levels.


response to oxygen levels

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of oxygen.


procyclogenesis

description: The morphological, biochemical and genetic changes that induce the differentiation of bloodstream form trypomastigotes into procyclic trypomastigotes in some of the Trypanosomatidae species such as Trypanosoma brucei. This process occurs inside the midgut of the tsetse fly vectors in T. brucei.


name: fibroblast growth factor receptor signaling pathway involved in spinal cord anterior/posterior pattern formation

description: The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands that results in the spatial identity of regions along the anterior-posterior axis of the spinal cord.


mannosamine biosynthetic process

description: The chemical reactions and pathways resulting in the formation of mannosomine, 2-amino-2-deoxymannose; the D-isomer is a constituent of neuraminic acids as well as mucolipids and mucoproteins.


acetylornithine deacetylase activity

description: Catalysis of the reaction: N2-acetyl-L-ornithine + H2O = acetate + L-ornithine.


name: wobble position uridine ribose methylation

description: The process in which the ribose of uridine at position 34 in the anticodon of a tRNA is post-transcriptionally methylated at the 2'-O position.


histone H2A methyltransferase activity

description: Catalysis of the reaction: S-adenosyl-L-methionine + a histone H2 = S-adenosyl-L-homocysteine + a methylated histone H2A. Histone methylation generally occurs on either an arginine or a lysine residue.


name: kaempferol O-glucoside biosynthetic process

description: The chemical reactions and pathways leading to the formation of O-glucosylated derivatives of kaempferol.


description: The series of molecular signals initiated by thrombopoietin binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.


protein urmylation

description: Covalent attachment of the ubiquitin-like protein URM1 to another protein.


alpha1-adrenergic receptor activity

description: Combining with epinephrine or norepinephrine to initiate a change in cell activity via activation of a G protein, with pharmacological characteristics of alpha1-adrenergic receptors; the activity involves transmitting the signal to the Gq alpha subunit of a heterotrimeric G protein.


synaptic transmission, GABAergic

description: The vesicular release of gamma-aminobutyric acid (GABA). from a presynapse, across a chemical synapse, the subsequent activation of GABA receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse.


name: regulation of DNA-templated DNA replication

description: Any process that modulates the rate, frequency, or extent of DNA-templated DNA replication, the process in which new strands of DNA are synthesized.


antisense RNA metabolic process

description: The chemical reactions and pathways involving antisense RNA, an RNA molecule complementary in sequence to another RNA or DNA molecule, which, by binding the latter, acts to inhibit its function and/or completion of synthesis.


corticospinal neuron axon guidance

description: The process in which the migration of an axon growth cone of a neuron that is part of the corticospinal tract is directed from the cerebral cortex layer V to the spinal cord dorsal funiculus in response to a combination of attractive and repulsive cues.


leptin receptor activity

description: Combining with the fat-cell specific hormone leptin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


long-chain fatty acid metabolic process

description: The chemical reactions and pathways involving a long-chain fatty acid. A long-chain fatty acid has an aliphatic tail containing 13 to 22 carbons.


icosa-5,8,12,14-tetraenoic acid

Any icosatetraenoic acid with the double bonds at positions 5, 8, 12 and 14.


icosatetraenoic acid

A 20-carbon, polyunsaturated fatty acid having four double bonds at unspecified positions.


icosa-5,8,11,13-tetraenoic acid

Any icosatetraenoic acid with the double bonds at positions 5, 8, 11 and 13.


all-cis-8,11,14,17-icosatetraenoic acid

An icosatetraenoic acid having four cis double bonds at positions 8, 11, 14 and 17.


(5Z,8Z,10E,12E)-icosatetraenoic acid

An icosatetraenoic acid in which the four double bonds are located at positions 5, 8, 10 and 12 (the 5Z,8Z,10E,12E-isomer).


icosa-5,8,10,14-tetraenoic acid

Any icosatetraenoic acid with the double bonds at positions 5, 8, 10 and 14.


icosa-6,8,10,14-tetraenoic acid

Any icosatetraenoic acid with the double bonds at positions 6, 8, 10 and 14.


icosa-5,7,11,14-tetraenoic acid

Any icosatetraenoic acid with the double bonds at positions 5, 7, 11 and 14.


icosa-7,9,11,14-tetraenoic acid

Any icosatetraenoic acid with the double bonds at positions 7, 9, 11 and 14.


icosa-5,9,11,14-tetraenoic acid

Any icosatetraenoic acid with the double bonds at positions 5, 9, 11 and 14.


(5Z,11Z,14Z,17Z)-icosatetraenoic acid

An icosatetraenoic acid in which the four double bonds have Z configuration and are located at positions 5, 11, 14 and 17.


icosa-6,8,11,14-tetraenoic acid

Any icosatetraenoic acid with the double bonds at positions 6, 8, 11 and 14.


icosa-5,8,11,14-tetraenoic acid

Any icosatetraenoic acid with the double bonds at positions 5, 8, 11 and 14.


(R)-tetraconazole

A 1-[2-(2,4-dichlorophenyl)-3-(1,1,2,2-tetrafluoroethoxy)propyl]1,2,4-triazole that is the (R)-enantiomer of tetraconazole.


TETRACONAZOLE

A racemate comprising equal amounts of (R)- and (S)-tetraconazole.  A fungicide used to control a range of fungal infections including powdery mildew, rusts, bunt, loose smut and scab.


(S)-tetraconazole

A 1-[2-(2,4-dichlorophenyl)-3-(1,1,2,2-tetrafluoroethoxy)propyl]1,2,4-triazole that is the (S)-enantiomer of tetraconazole.


name: Bilateral Synchronous Sporadic Renal Cell Carcinoma

category: biolink:Disease biolink:DiseaseOrPhenotypicFeature biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing

description: Non-hereditary renal cell carcinoma arising from a kidney and detected in the other kidney within six months of the first primary. The majority are clear cell renal cell carcinomas.


Kidney Germ Cell Tumor

description: A rare benign or malignant germ cell tumor that arises from the kidney.


MAGNESIUM CHLORIDE

A hydrate that is the hexahydrate form of magnesium dichloride.


methyl p-hydroxybenzoate

A 4-hydroxybenzoate ester resulting from the formal condensation of the carboxy group of 4-hydroxybenzoic acid with methanol. It is the most frequently used antimicrobial preservative in cosmetics. It occurs naturally in several fruits, particularly in blueberries.


paraben

A 4-hydroxybenzoate ester in which the esterifying alcohol is an alkanol (in diagram, R = alkyl). Commonly used as preservatives in cosmetic and pharmaceutical products.


propylparaben

The benzoate ester that is the propyl ester of 4-hydroxybenzoic acid.   Preservative typically found in many water-based cosmetics, such as creams, lotions, shampoos and bath products. Also used as a food additive.


ethyl hydroxybenzoate

An ethyl ester resulting from the formal condensation of the carboxy group of 4-hydroxybenzoic acid with ethanol,


Arteriovenous graft thrombosis

description: Partial or complete occlusion of the lumen of an arteriovenous graft by a thrombus.


A steroidal acyl-CoA that results from the formal condensation of the thiol group of coenzyme A with the carboxy group of 3-oxochenodeoxycholic acid.


calixfurans

Compounds containing a calixfuran skeleton.


calixfuran

A macrocycle composed of furan-2,5-diyl groups linked by methylene groups. The number of furan-2,5-diyl units in the macrocycle is denoted by the "n" in calix[n]furan name.


name: Refractory Childhood Acute Lymphoblastic Leukemia

description: Acute lymphoblastic leukemia that occurs in childhood and does not respond to treatment.


Mullerian inhibiting factor deficiency

description: A deficiency of the Mullerian inhibiting substance, which is secreted by the Sertoli cells during embryogenesis. It can result in unilateral or bilateral cryptorchidism, testicular regression syndrome and sterility.


Childhood Acute Basophilic Leukemia

description: An acute basophilic leukemia occurring in children.


A 1-phosphatidyl-1D-myo-inositol in which the phosphatidyl acyl groups at positions 1 and 2 are specified as (8Z,11Z,14Z,17Z)-icosatetraenoyl and octadecanoyl respectively.


Sinonasal Solitary Fibrous Tumor

description: A solitary fibrous tumor that arises from the nasal cavity and paranasal sinuses.


HIRSUTELLIDE A

A cyclodepsipeptide isolated from the cell extract of the entomopathogenic fungus Hirsutella kobayasii BCC 1660 and exhibits antimycobacterial and antimalarial activities.


borinic acid

The simplest borinic acid, consisting of borane with one of the hydrogens substituted by a hydroxy group.


A tetrachlorobiphenyl that is biphenyl in which the hydrogens at position 3 and 4 on each phenyl group are replaced by chlorines.


nitroxoline

A monohydroxyquinoline in which the hydroxy group is positioned at C-8 with a nitro group trans to it at C-5.


Supernumerary Hemivertebra

description: More than the usual or expected number of hemivertebra.


(R)-glycol nucleic acid

Glycol nucleic acids with an (R) chiral centre in the glycol backbone. They can be synthetically derived from (R)-(+)-glycidol.


organic vanadium salt

A vanadium salt with C-H bonds


A member of the class of phenylureas that is urea in which one of the nitrogens bears a 3-tert-butyl-1-[(3S)-3-carboxy-1,2,3,4-tetrahydroisoquinolin-6-yl]-1H-pyrazol-5-yl substituent, while the other bears a 2,3-dichlorophenyl group.


A 3beta-hydroxy steroid that is cathasterone which is lacking the oxo substituent at position 6.


name: Malignant neoplasm of hypopharynx recurrent

description: The reemergence of a hypopharyngeal malignant neoplasm after a period of remission.


Benign neoplasm of pyriform sinus

description: A neoplasm that arises from the pyriform sinus and is characterized by the absence of atypical or malignant cytological and architectural features, and absence of invasive features or metastatic potential.


Neoplasm of pyriform sinus

description: A benign or malignant neoplasm that affects the pyriform sinus.


A N-acylglycine that is glycine substituted by a 2-methylbutanoyl group at the N atom.


A steroid acid that is 5beta-cholestan-26-oic acid which is substituted by hydroxy groups as the 3alpha, 7alpha, and 12alpha positions.


name: 3,3-Dimethyl allyl-p-propenyl phenyl ether


CONIINE

A 2-propylpiperidine that has S-configuration.


ETHION

An organic thiophosphate that is S,S'-methanediyl bis[dihydrogen (phosphorodithioate)] in which all the hydroxy groups have been converted to their corresponding ethyl esters respectively. Ethion is an organophosphate insecticide with inhibitory activity towards the enzyme acetylcholinesterase ( EC 3.1.1.7).


An unsaturated fatty acyl-CoA that results from the formal condensation of the thiol group of coenzyme A with the carboxy group of (2E,11Z,14Z,17Z)-icosatetraenoic acid.


TRIDECANE

A straight chain alkane containing 13 carbon atoms. It forms a component of the essential oils isolated from plants such as Abelmoschus esculentus.


A triazolopyrimidine that is [1,2,3]triazolo[4,5-d]pyrimidine bearing an amino substituent at position 7.


A heteroarenecarbaldehyde that is indole in which the hydrogen at position 4 has been replaced by a formyl group.


LEHUALIDE F

A member of the class of 2-pyranones that is 2H-pyran-2-one substituted by a methoxy group at position 3, a hydroxy group at position 4, a methyl group at position 5 and a (2E)-3-methyl-9-phenylnon-2-en-1-yl group at position 6. Isolated from the marine sponge of the genus Plakortis, it exhibits cytotoxicity against human promyeloid leukemic HL-60 cells.


mycinamicin VI

A mycinamicin composed of a 16-membered ring macrolactone core, an N,N-dimethylated deoxysugar desosamine and a 6-deoxysugar 6-deoxyallose.


Resectable Carcinoma

description: Carcinoma that is amenable to surgical resection.


name: Resectable Cutaneous Squamous Cell Carcinoma of the Head and Neck

description: Cutaneous squamous cell carcinoma of the head and neck that is amenable to surgical resection.


Resectable Periampullary Adenocarcinoma

description: Periampullary adenocarcinoma that is amenable to surgical removal.


name: Resectable Liver and Intrahepatic Bile Duct Carcinoma

description: Liver carcinoma that is amenable to surgical resection.


Resectable Merkel Cell Carcinoma

description: Merkel cell carcinoma that is amenable to surgical resection.


Resectable Digestive System Carcinoma

description: Digestive system carcinoma that is amenable to surgical resection.


Resectable Skin Squamous Cell Carcinoma

description: Skin squamous cell carcinoma that is amenable to surgical resection.


name: Localized Resectable Adult Liver Carcinoma

description: A localized hepatocellular carcinoma or intrahepatic cholangiocarcinoma that occurs during adulthood and it is amenable to surgical resection.


name: Resectable Head and Neck Squamous Cell Carcinoma

description: Squamous cell carcinoma of the head and neck which is amendable to surgical removal.


name: Resectable Ampulla of Vater Adenocarcinoma

description: Ampulla of Vater adenocarcinoma that is amenable to surgical resection.


Resectable Appendix Carcinoma

description: Appendix carcinoma that is amenable to surgical resection.


Resectable Gastric Adenocarcinoma

description: Gastric adenocarcinoma that is amenable to surgical resection.


Resectable Endometrial Carcinoma

description: Endometrial carcinoma that is amenable to surgical resection.


Resectable Skin Carcinoma

description: Skin carcinoma that is amenable to surgical resection.


Small intestine carcinoma resectable

description: Carcinoma of the small intestine amendable to resection.


Resectable Colon Carcinoma

description: Colon carcinoma that is amenable to surgical resection.


Resectable Esophageal Carcinoma

description: Esophageal carcinoma that is amenable to surgical resection.


Resectable Gallbladder Adenocarcinoma

description: Gallbladder adenocarcinoma that is amenable to surgical resection.


name: Localized Resectable Adult Hepatocellular Carcinoma

description: A localized hepatocellular carcinoma that occurs during adulthood and it is amenable to surgical resection.


name: Resectable Gastroesophageal Junction Adenocarcinoma

description: Gastroesophageal junction adenocarcinoma that is amenable to surgical resection.


Resectable Cervical Carcinoma

description: Cervical carcinoma that is amenable to surgical resection.


Carcinoma duodenum resectable

description: Carcinoma of the duodenum amendable to surgical removal.


Resectable Colorectal Carcinoma

description: Colorectal carcinoma that is amenable to surgical resection.


Carcinoma liver resectable

description: A hepatocellular carcinoma that is amenable to surgical resection.


Resectable Esophageal Adenocarcinoma

description: Esophageal adenocarcinoma that is amenable to surgical resection.


Resectable Bladder Urothelial Carcinoma

description: Bladder urothelial carcinoma that is amenable to surgical resection.


(3R,4S)-4-hydroxy-L-isoleucine residue

An L-isoleucine residue that is substituted by an hydroxy group at position 4 (the 3R,4S diastereoisomer).


A linear amino pentasaccharide consisting of alpha-fucosyl, beta-galactosyl, beta-glucosaminyl,  beta-galactosyl and glucose units connected via sequential (1->2)-, (1->4)-, (1->3)- and (1->4)-linkages.


asenapine maleate

A racemate consisting of equal amounts of (R,R)- and (S,S)-asenapine maleate. Used for the acute treatment of schizophrenia and acute treatment of manic or mixed episodes associated with bipolar I disorder with or without psychotic features.


A secondary fatty alcohol that is henicosane substituted by a hydroxy group at position 2.


name: 5-[4-[methyl-[(3-methyl-2-thiophenyl)methyl]amino]-6-quinazolinyl]-2-furancarboxylic acid ethyl ester


A dihydroceramide in which the ceramide N-acyl group is specified as (15Z)-tetracosenoyl (nervonoyl).


name: Childhood Cerebellar Anaplastic Astrocytoma

description: A cerebellar anaplastic astrocytoma that occurs during childhood.


a hydroxy phosphatidylcholine

Any phosphatidylcholine carrying one or more hydroxy substituents.


sulcofuron-sodium

The sodium salt of sulcofuron.


morellic acid

A dioxo monocarboxylic acid derived from morellin by oxidation of the aldehyde group to the corresponding carboxy group. Isolated from Garcinia morella and Garcinia hanburyi, it exhibits antineoplastic, antibacterial and anti-HIV activity.


name: 3-(1,3-benzodioxol-5-yl)-2-propenoic acid [2-(cyclopropylamino)-2-oxoethyl] ester


1-Aminocyclopropane carboxylic acid

A non-proteinogenic alpha-amino acid consisting of cyclopropane having amino and carboxy substituents both at the 1-position.


A member of the class of monohydroxy-1,4-benzoquinones that is embelin in which the hydroxy group at position 5 is replaced by a methoxy group. Isolated from Lysimachia punctata and Embelia ribes, it exhibits antileishmanial activity as well as inhibitory activity towards hepatitis C protease.


A 2-pyranone in which the hydrogens at positions 4 and 6 of 2H-pyran-2-one are replaced by hydroxy and 2-oxotridecyl groups respectively.


pApA

A 5'-phospho-(3'->5')-dinucleotide composed from two AMP residues.


benzenediazonium

The aromatic diazonium ion formed from diazotisation of aniline.


A 4-hydroxy-D-proline in which the hydroxy group at position 4 has S-configuration.


Stage II Lip Cancer AJCC v6 and v7

description: Stage II includes: T2, N0, M0. T2: Tumor more than 2 cm but not more than 4 cm in greatest dimension.  N0: No regional lymph node metastasis.  M0: No distant metastasis. (AJCC 6th and 7th eds.)


D-xylonic acid

A xylonic acid with D configuration.


Lower Gingival Verrucous Carcinoma

description: A verrucous carcinoma of the oral cavity that arises from the lower gingiva.


name: Verrucous carcinoma of the oral cavity recurrent

description: Reemergence of verrucous carcinoma of the oral cavity after a period of remission.


Tongue Verrucous Carcinoma

description: A well differentiated squamous cell carcinoma arising from the tongue.  It is an exophytic, warty, slow growing tumor, usually affecting older males. It is associated with the chronic use of smokeless tobacco.


Buccal Mucosa Verrucous Carcinoma

description: A verrucous carcinoma of the oral cavity that arises from the buccal mucosa.


Oral Cavity Carcinoma Cuniculatum

description: A variant of well-differentiated squamous cell carcinoma arising from the oral cavity. It is characterized by the presence of minimal cytological atypia, multiple keratin-filled crypts, and intraepithelial neutrophils.


Upper Gingival Verrucous Carcinoma

description: A verrucous carcinoma of the oral cavity that arises from the upper gingiva.


A carbohydrazide obtained by formal condensation of the carboxy group of 4-hydroxybenzoic acid with hydrazine.


Anoro Ellipta

A mixture composed of umeclidinium bromide and vilanterol (trade name Breo Anoro) that is used for long-term maintenance treatment of airflow obstruction in patients with chronic obstructive pulmonary disease.


The S-(trans-4-carboxybut-2-enoyl) derivative of coenzyme A.


(R)-methyl phenyl sulfoxide

A (methylsulfinyl)benzene that has R configuration at the chiral sulfur.


An androstanoid that is testosterone substituted at C2  by a hydroxy group with undefined stereochemistry.


An androstanoid that is testosterone carrying an additional hydroxy substituent at the 2beta-position.


gossypin

A glycosyloxyflavone that is  gossypetin attached to a beta-D-glucopyranosyl residue at position 8 via a glycosidic linkage.


An oligosaccharide sulfate consisting of 3-O-sulfo-beta-D-galactopyranose and -2-acetamido-2-deoxy-D-glucopyranose residues joined by a (1->4) glycosidic bond.


laminarabiose

A glycosylglucose consisting of D-glucose with undefined anomeric stereochemistry and a beta-D-glucosyl residue attached at the 3-position.


A laminarabiose having beta-configuration at the reducing end anomeric centre.


A glycotriaosylceramide having N-propionyl-beta-D-galactosyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosyl as the triaosyl component.


A glycotetraosylceramide having beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucose as the tetrasaccharide component.


A glycotetraosylceramide having a beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc component attached to the primary hydroxy function of a ceramide with undefined sphingoid base and fatty acyl chain.


name: 4-[[(4-methoxyanilino)-oxomethyl]amino]benzoic acid methyl ester


A 1,2-diacyl-3-alpha-D-galactosyl-sn-glycerol in which the groups at the 1- and 2-positions are both oleoyl.


A ketoaldehyde that is pentanal substituted by an oxo group at position 4.


cisplatin

A diamminedichloroplatinum compound in which the two ammine ligands and two chloro ligands are oriented in a cis planar configuration around the central platinum ion. An anticancer drug that interacts with, and forms cross-links between, DNA and proteins, it is used as a neoplasm inhibitor to treat solid tumours, primarily of the testis and ovary. Commonly but incorrectly described as an alkylating agent due to its mechanism of action (but it lacks alkyl groups).


A carboxyalkyl phosphate consisting of D-glyceric acid having an alpha-D-glucosyl residue at the 2-position and a phospho group at the 3-position


D-glucosyl-N-hexanoylsphingosine

A D-glucosyl-N-acylsphingosine in which the ceramide N-acyl group is specified as hexanoyl.


The zwitterion formed by transfer of a proton from the OH of the phospho group to the alanyl amino nitrogen.


A zwitterion obtained by transfer of a proton from the phosphate to the amino group of any 1,2-diacyl-sn-glycero-3-phospho-1'-(3'-O-L-alanyl)-sn-glycerol.


hydramacrophyllol A

An isobenzofuranone that is 2-benzofuran-1(3H)-one substituted by a hydroxy group at position 7 and a (S)-hydroxy(4-hydroxyphenyl)methyl group at position 3. It has been isolated from the roots of Scorzonera judaica.


An amino acid zwitterion arising from transfer of a proton from the carboxy to the amino group of 4-(3-methylbut-2-enyl)-L-abrine.


cryptocyanin cation

A cationic C3-cyanine type compound with 1-ethylquinolin-4-yl groups at both ends.


3-O-beta-D-glucosyl-D-glucuronic acid

A disaccharide consisting beta-D-glucosyl and D-glucuronic acid residues joined by a (1->3)-linkage.


Refractory Hairy Cell Leukemia Variant

description: Hairy cell leukemia variant that is resistant to treatment.


name: HHV-8-Associated Multicentric Castleman Disease

description: Multicentric Castleman disease associated with HHV8 infection.


A deoxypentose that is D-ribofuranose in which the hydroxy group at position C-2 is replaced by hydrogen.


Sellar Chondroid Chordoma

description: A chondroid chordoma that arises from the sellar region.


Conventional Chordoma

description: A malignant bone tumor arising from the remnants of the fetal notochord. It is characterized by the presence of large epithelioid cells with clear to light eosinophilic cytoplasm. Some of the cells are large with bubbly, vacuolated cytoplasm (physaliphorous cells). The cells form cords and nests that are embedded within an extracellular myxoid matrix.


A thiohydroximic acid in which the C-substituent is specified as (3-indolyl)methyl (the E-geoisomer).


A glycophytoceramide having an alpha-D-galactopyranosyl residue at the O-1 position and a 15-phenylpentadecanoyl group attached to the nitrogen.


(E)-hex-2-enyl acetate

An acetate ester resulting from the formal condensation of the hydroxy group of (E)-hex-2-en-1-ol with the carboxy group of acetic acid.


An N-acyl-L-alanine resulting from the formal condensation of the amino group of L-alanine with the carboxy group of (15S)-hydroperoxy-(5Z,8Z,11Z,13E)-icosatetraenoic acid.


dicamba-methyl

The methyl ester of dicamba.


remdesivir triphosphate

An organic triphosphate that is GS-441524 in which the 5'-hydroxy group has been replaced by a triphosphate group. It is the active metabolite of remdesivir.


description: An adenocarcinoma that arises from the sinonasal tract. It is characterized by the absence of features that resemble intestinal adenocarcinoma.


A 1,2-diacyl-sn-glycerol 3-phosphate in which the phosphatidyl acyl groups at postions 1 and 2 are specified as heptadecanoyl and lauroyl respectively.


Recurrent Malignant Mastocytosis

description: The reemergence of malignant mastocytosis after a period of remission.


Recurrent Mast Cell Leukemia

description: The reemergence of mast cell leukemia after a period of remission.


Zwitterionic form N-(6-aminohexanoyl)-6-aminohexanoic acid.


The simplest member of the class of propane-1,3-diols, consisting of propane in which one hydrogen from each methyl group is substituted by a hydroxy group. A colourless, viscous, water-miscible liquid with a high (210degreeC) boiling point, it is used in the synthesis of certain polymers and as a solvent and antifreeze.


Asp-Phe-Val-Val

A tetrapeptide composed of L-aspartic acid, L-phenylalanine and two L-valine units joined in sequence by peptide linkages.


Sellar Gangliocytoma

description: A tumor that arises in the sellar region and is characterized by the presence of mature ganglion cells and neuronal differentiation. It is often associated with the presence of pituitary neuroendocrine tumors/adenomas.


Double-Negative Prostate Carcinoma

description: A metastatic, castration-resistant prostate carcinoma that is composed of fibroblast growth factor-driven malignant cells.


name: Castration-Resistant Prostate Carcinoma Refractory to Second-Generation Androgen Receptor Axis-Targeted Agents

description: Castration-resistant prostate carcinoma which is refractory to second-generation androgen receptor axis-targeted agents, namely abiraterone and enzalutamide.


name: Intermediate Atypical Prostate Carcinoma

description: An aggressive, castration-resistant, histologically distinct, metastatic carcinoma arising from the prostate gland. It is characterized by the presence of a pure population of cytologically bland malignant epithelial cells with moderate to abundant cytoplasm and rare mitotic figures. The prognosis is poor.


Aggressive Variant Prostate Carcinoma

description: A lethal form of advanced castration-resistant prostate carcinoma that emerges in the later stages of castration-resistant treatment. It is an adaptive response to androgen receptor pathway inhibition. The morphologic features vary, ranging from poorly differentiated carcinomas to mixed adenocarcinoma-small cell carcinomas to pure small cell carcinomas expressing neuroendocrine markers. Clinically, it manifests with rapidly progressive disease, visceral or lytic bone metastases and bulky tumor masses. Molecular studies have shown the loss of tumor suppressor genes TP53 and RB1.


A synthetic beta-D-glucoside that is a branched pentadecasaccharide derivative consisting of three beta-D-Glc-(1->6)-[alpha-L-Rha-(1->3)]-alpha-D-Glc-(1->3)-alpha-L-Rha2Ac-(1->3)-beta-D-GlcNAc pentasaccharide units linked (1->4) between the GlcNac residue at the reducing end of one unit and the OH at position 4 of the alpha-D-glucose residue of the adjacent unit. An aminoethyl linker from the reducing-end GlcNAc residue allows for efficient conjugation to a carrier protein.


A glycohexaosylceramide having alpha-L-Fuc-(1->2)-beta-D-Gal-(1->3)-beta-D-GalNAc-(1->3)-alpha-D-Gal-(1->4)-beta-D-Gal-(1->4)-beta-D-Glc as the glycohexaosyl component.


Advanced Unfavorable Hodgkin Lymphoma

description: An advanced Hodgkin lymphoma with unfavorable prognosis.


tubocapsanolide F

A  withanolide that is 5,6:22,26-diepoxyergosta-2,24-diene-1,26-dione substituted by hydroxy groups at positions 4 and 17 (the 4beta,5beta,6beta,22R stereoisomer). Isolated from Tubocapsicum anomalum, it exhibits cytotoxic activity.


allylamine antifungal drug

An organonitrogen compound that contains an amino group that is attached to a carbon which is itself attached to an olefinic carbon and which has been used as an antifungal drug.


TERBINAFINE HYDROCHLORIDE

A hydrochloride obtained by reaction of terbinafine with one molar equivalent of hydrogen chloride.


Situs inversus thoracis

description: A congenital condition in which there is complete right-to-left reversal of the position of the thoracic organs.


ethyl-dUTP

An organic triphosphate formed by condensation between the gamma-phospho group of 2'-deoxyuridine 5'-triphosphate and ethanol.


citral

An enal that consists of octa-2,6-dienal bearing methyl substituents at positions 3 and 7. A mixture of the two geometric isomers geranial and neral, it is the major constituent (75-85%) of oil of lemon grass, the volatile oil of Cymbopogon citratus, or of C. flexuosus. It also occurs in oils of verbena, lemon, and orange.


thiocyclam hydrochloride

A hydrochloride salt resulting from the formal reaction of equimolar amounts of thiocyclam and hydrogen chloride. A nicotinic acetylcholine receptor agonist used as a broad-spectrum insecticide. Not approved for use within the European Union.


Urethritis Glandularis

description: A reactive inflammatory disorder affecting the urethra.  It is characterized by the development of small cysts in the urethral wall.  The cysts are lined by metaplastic glandular cells.


magnesium oxide nanocrystal

A nanocrystal composed of magnesium oxide.


Dialysis Catheter Tunnel Infection

description: Local infection involving the subcutaneously tunneled portion of a dialysis catheter.


chlorquinaldol

A monohydroxyquinoline that is quinolin-8-ol which is substituted by a methyl group at position 2 and by chlorine at positions 5 and 7. An antifungal and antibacterial, it was formerly used for topical treatment of skin conditions and vaginal infections.


A 1-(Z-alk-1-enyl)-sn-glycero-3-phosphoglycerol in which the non-alkylated glycerol moiety has R-configuration.


A member of the class of glycerophosphoglycerols that is sn-glycero-3-phosphoglycerol carrying an unspecified Z-alk-1-enyl substituent at position 1


lysophosphatidylglycerol (P-34:3/0:0)

A 1-(Z-alk-1-enyl)-sn-glycero-3-phosphoglycerol in which the alkenyl group contains 34 carbons and has 3 additional double bonds.


An alpha-amino-acid residue anion obtained by deprotonation of the carboxy and phosphate groups of C-terminal-gamma-L-glutamyl-L-2-aminoadipic acid 6-phosphate group. Major structure at pH 7.3


phytoestrogen

Any compound produced by a plant that happens to have estrogenic activity.


name: Oncocytic Variant of Chromophobe Renal Cell Carcinoma

description: A rare variant of chromophobe renal cell carcinoma that exhibits oncocytoma-like features.


name: Lugano Classification Stage IV Adult Hodgkin Lymphoma AJCC v8

description: Stage IV: Diffuse or disseminated involvement of one or more extralymphatic organs, with or without associated lymph node involvement; or noncontiguous extralymphatic organ involvement in conjunction with nodal stage II disease; or any extralymphatic organ involvement in nodal stage III disease. Stage IV includes any involvement of the CSF, bone marrow, liver, or lungs (other than by direct extension in stage IIE disease). (from AJCC 8th Ed.)


name: Lugano Classification Stage IV Adult Lymphoma AJCC v8


A mannotetrose consisting of four alpha-D-mannopyranose residues linked by three (1->6) glycosidic bonds.


An alpha-D-Galp-(1->3)-D-GalpNAc in which the anomeric centre at the reducing end has beta-configuration.


An inositol phosphomannosylinositol phosphoceramide compound having a tetracosanoyl group attached to the ceramide nitrogen, hydroxylation at C-4 of the long-chain base, and hydroxylation at C-2 and C-3 of the very-long-chain fatty acid.


cadmium dichloride

A cadmium coordination entity in which cadmium(2+) and Cl(-) ions are present in the ratio 2:1. Although considered to be ionic, it has considerable covalent character to its bonding.


ESOXYBUTYNIN

A 4-(diethylamino)but-2-yn-1-ol yhat has S configuration. In contrast to the (R)- enantiomer, esoxybutynin exhibits essentially no anticholinergic activity.


A 17-oxo steroid that is 5alpha-androstan-17-one substituted by a beta-hydroxy group at positions 3 and an alpha-hydroxy group at position 7.


name: Postneoadjuvant Therapy Stage IVB Gastroesophageal Junction Adenocarcinoma AJCC v8

description: Stage IVB includes: Any T, Any N, M1. M1: Distant metastasis. (AJCC 8th ed.)


(2E,11R)-11-hydroxydodec-2-enoic acid

An (omega-1)-hydroxy fatty acid that is trans-2-dodecenoic acid in which the 11-pro-R hydrogen is replaced by a hydroxy group.


An alkene that is 2-methylhept-1-ene carrying a methyl group at position 4.


A diblock copolymer composed of adjacent blocks of poly(ethylene glycol) and poly(glycerol 1-O-monomethacrylate).


palladium nanoparticle

A nanoparticle consisting of palladium atoms.


A monovalent inorganic cation obtained from cobalt.


Astrocytoma, Not Otherwise Specified

description: A central nervous system tumor with morphological features of astrocytoma in which there is insufficient information on the IDH genes status.


A single-stranded DNA polynucleotide consisting of a repeating unit of thymidine and 5-methyldeoxycytidine residues, with all residues connected by 3'->5' phosphodiester linkages.


brompheniramine

Pheniramine in which the hydrogen at position 4 of the phenyl substituent is substituted by bromine. A histamine H1 receptor antagonist, brompheniramine is used (commonly as its maleate salt) for the symptomatic relief of allergic conditions, including rhinitis and conjunctivitis.


dexbrompheniramine

The (pharmacologically active) (S)-(+)-enantiomer of brompheniramine. A histamine H1 receptor antagonist, it is used (commonly as its maleate salt) for the symptomatic relief of allergic conditions, including rhinitis and conjunctivitis.


(2S,3R,11S)-aszonalenin zwitterion

Major microspecies at pH 7.3.


alpha-L-Fucp-(1->2)-beta-D-Galp6S-(1->4)-D-Glcp in which the anomeric configuration of the glucose residue at the reducing end is beta.


name: Ciliary Body Benign Teratoid Medulloepithelioma

description: A rare, unilateral, benign embryonal neoplasm typically presenting as a ciliary body mass during childhood. It arises from primitive medullary epithelium and contains heterologous elements, particularly cartilage, skeletal muscle, and brain tissue.


Recurrent Extragonadal Seminoma

description: The reemergence of extragonadal seminoma after a period of remission.


name: Recurrent Malignant Extragonadal Germ Cell Tumor

description: The reemergence of malignant extragonadal germ cell tumor after a period of remission.


name: Recurrent Malignant Extragonadal Nongerminomatous Germ Cell Tumor

description: The reemergence of a malignant extragonadal nongerminomatous germ cell tumor after a period of remission.


Stage IA Cervical Cancer FIGO 2018

description: Invasive cervical carcinoma that can be diagnosed only by microscopy, with maximum depth of invasion less than 5 mm. (FIGO 2018)


Stage IA2 Cervical Cancer FIGO 2018

description: Cervical carcinoma with measured stromal invasion equal or more than 3 mm and less than 5 mm in depth. (FIGO 2018)


Stage IA1 Cervical Cancer FIGO 2018

description: Cervical carcinoma with measured stromal invasion less than 3 mm in depth. (FIGO 2018)


BENZO[DEF]CHRYSENE

An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.


coronene

A ortho- and peri-fused polycyclic arene that consists of six peri-fused benzene rings.


FLUORANTHENE

An ortho- and peri-fused polycyclic arene consisting of a naphthalene and benzene unit connected by a five-membered ring.


BENZO[E]PYRENE

An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings. It is listed as a Group 3 carcinogen by the IARC.


perylene

An ortho- and peri-fused polycyclic arene comprising of five benzene rings that is anthracene in which the d,e and k,l sides are fused to benzene rings.


acenaphthylene

A ortho- and peri-fused tricyclic hydrocarbon that occurs in coal tar.


BENZO[B]FLUORANTHENE

An ortho- and peri-fused polycyclic arene that consists of a benzene ring fused with a acephenanthrylene ring.


PYRENE

An ortho- and peri-fused polycyclic arene consisting of four fused benzene rings, resulting in a flat aromatic system.


A pentacyclic ortho- and peri-fused polycyclic arene consisting of a dihydrocyclopenta[ij]tetraphene ring system with a methyl substituent at the 3-position.


The D-enantiomer of 4-hydroxyleucine.


A leucine derivative that is leucine substituted by a hydroxy group at position 4.


The L-enantiomer of 4-hydroxyleucine.


An amino trisaccharide consisting of N-acetyl-alpha-D-glucosamine, beta-D-galactose and N-acetyl-beta-D-glucosamine residues linked sequentially (1->6) and (1->4).


name: 2-amino-1-[2-(4-morpholinyl)ethyl]-3-pyrrolo[3,2-b]quinoxalinecarboxylic acid ethyl ester


QUINOXALINE

A naphthyridine in which the nitrogens are at positions 1 and 4.


rhosin

A D-tryptophan derivative obtained by formal condensation of the carboxy group of D-tryptophan with the amino group of (quinoxalin-6-yl)methylidenehydrazide. It directly targets the Rho GEF binding domain, thereby preventing Rho from interacting with its GEFs


name: 2-cyano-2-[3-(4-morpholinyl)-2-quinoxalinyl]acetic acid cyclohexyl ester


quinoxaline pesticide

A quinoxaline derivative that has pesticidal properties.


QUIZALOFOP ETHYL ESTER

An ethyl ester resulting from the formal condensation of the carboxy group of 2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoic acid with ethanol.


PROPAQUIZAFOP

A quinoxaline derivative used as systemic herbicide for annual and perennial grasses.


2-methylquinoxaline-6-carboxylic acid

A quinoxaline derivative in which the quinoxaline (1,4-naphthyridine) skeleton is substituted with a carboxy function at C-6 and a methyl group at C-2.


name: 1-[3-[1-cyano-2-oxo-2-[(phenylmethyl)amino]ethyl]-2-quinoxalinyl]-3-piperidinecarboxylic acid ethyl ester


PI 3-Kg inhibitor

A quinoxaline derivative  that is quinoxaline in which the hydrogen at position 6 is replaced by a (2,4-dioxo-1,3-thiazolidin-5-ylidene)methyl group. It is a potent inhibitor of the PI3Kgamma, with an IC50 of 8 nM and inhibits the progression of joint inflammation and damage in both lymphocyte-independent and dependent mouse models of rheumatoid arthritis.


QUIZALOFOP-P-ETHYL

An ethyl 2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate that has R configuration. A proherbicide for quizalofop-P, it is used to control annual and perennial grass weeds in a variety of crops, including potatoes, sugar beet, peanuts, cotton and flax.


name: 3-(4-butyl-3-oxo-2-quinoxalinyl)propanoic acid [2-(3-chloro-4-fluoroanilino)-2-oxoethyl] ester


name: 3-pyridinecarboxylic acid (3-acetyl-4-oxido-2-quinoxalin-4-iumyl)methyl ester


A hydroxyquinoxaline that consists of quinoxaline having a single hydroxy substituent located at position 2.


name: N-[(1-hydroxy-4-oxido-2-quinoxalin-4-iumylidene)methylimino]carbamic acid methyl ester


(S)-quizalofop

A 2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoic acid that has S configuration. It is the (inactive) enantiomer of the herbicide quizalofop-P.


name: 4-chlorobenzoic acid 2-(2-amino-3-cyano-1-pyrrolo[3,2-b]quinoxalinyl)ethyl ester


(+)-cyclazosin

A monocarboxylic acid amide obtained by formal condensation of the carboxy group of furoic acid with the secondary amino group of 6,7-dimethoxy-2-[(4aR,8aS)-octahydroquinoxalin-1-yl]quinazolin-4-amine.


QUIZALOFOP

A monocarboxylic acid that is 2-phenoxypropanoic acid in which the phenyl group is substituted at the para position by a (6-chloroquinoxalin-2-yl)oxy group.


name: 4-[[[2,3-bis(2-pyridinyl)-6-quinoxalinyl]amino]-oxomethyl]-1-piperazinecarboxylic acid ethyl ester


name: 2-(3-oxo-4H-quinoxalin-2-yl)propanoic acid ethyl ester


A quinoxaline derivative in which quinoxalin-2(1H)-one carries an L-serine-based function {[(2S)-1-amino-3-hydroxy-1-oxopropan-2-yl]amino}-3-oxopropyl} at C-2. One of a series of mucosal-associated invariant T (MAIT) cell agonists.


CGP 78608

A phosphonic acid in which the hydrogen attached to phosphorous is substituted by a 1-{[(7-bromo-2,3-dioxo-1,2,3,4-tetrahydroquinoxalin-5-yl)methyl]amino}ethyl group. Potent and selective NMDA antagonist that acts through the glycine site (IC50 = 5 nM). Displays >500-fold selectivity over kainate and AMPA receptors (IC50 values are 2.7 and 3 muM respectively). Anticonvulsant in vivo following systemic administration.


(S)-quizalofop-ethyl

An ethyl 2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate that has S configuration.


name: 5-[[1-oxo-3-(3-oxo-4H-quinoxalin-2-yl)propoxy]methyl]-2-furancarboxylic acid ethyl ester


name: 4-[[3-[(4-chlorophenyl)sulfonylamino]-2-quinoxalinyl]amino]-1-piperidinecarboxylic acid ethyl ester


quinoxaline antifungal agent

A compound that has significant antifungal properties whose structure contains a quinoxaline moiety.


quizalofop-P-tefuryl

A tetrahydrofurylmethyl ester resulting from the formyl condensation of the carboxy group of quizalofop-P with the hydroxy group of tetrahydrofurfuryl alcohol.


name: 4-(2-quinoxalinylamino)benzoic acid ethyl ester


name: 6-quinoxalinecarboxylic acid phenyl ester


A quinoxaline derivative in which the quinoxaline (1,4-naphthyridine) skeleton is substituted with a methyl group at each of positions C-2 and C-3.


A quinoxaline derivative in which the quinoxaline (1,4-naphthyridine) skeleton is substituted at C-2 with a methyl group.


name: 2-cyano-2-[3-(4-morpholinyl)-2-quinoxalinyl]acetic acid hexyl ester


A quinoxaline derivative in which the quinoxaline (1,4-naphthyridine) skeleton is substituted at C-5 with a methyl group.


name: 2-amino-1-cyclohexyl-3-pyrrolo[3,2-b]quinoxalinecarboxylic acid ethyl ester


quizalofop-P

A 2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoic acid that has R configuration. An acetyl-CoA carboxylase inhibitor, it is used (generally as the corresponding ethyl or tefuryl ester proherbicides) for the control of annual and perennial grass weeds in sugar beet.


name: 2,3-dimethyl-6-quinoxalinecarboxylic acid (2-bromophenyl)methyl ester


quinoxaline herbicide

A quinoxaline pesticide that has herbicidal activity.


grazoprevir

An azamacrocyclic compound that is a hepatitis C protease inhibitor used in combination with elbasvir (under the brand name Zepatier) for treatment of chronic HCV genotypes 1 or 4 infection in adults.


voxtalisib

A sulfonamide obtained by formal condensation of the sulfonic acid group of 4-[(3-methoxy-4-methylbenzoyl)amino]benzenesulfonic acid with the primary aromatic amino group of N-(3,5-dimethoxyphenyl)quinoxaline-2,3-diamine. A dual PI3K/mTOR inhibitor used in cancer treatment.


An androstanoid that is 5alpha-dihydrotestosterone carrying an additional hydroxy susbstituent at position 19.


name: Stage I Pancreatic Neuroendocrine Tumor AJCC v8

description: Stage I includes: T1, N0, M0. T1: Tumor limited to the pancreas and measuring less than 2 cm. N0: No regional lymph node involvement. M0: No distant metastasis. (AJCC 8th ed.)


RILPIVIRINE HYDROCHLORIDE

A hydrochloride obtained by reaction of rilpivirine with one equivalent of hydrochloric acid. Used for treatment of HIV.


Infiltrating Intramuscular Lipoma

description: An infiltrating lipoma that affects skeletal muscle.  It has a higher rate of local recurrence.


name: Refractory Endometrial Dedifferentiated Carcinoma

description: Endometrial dedifferentiated carcinoma that is resistant to treatment.


Campylobacter jejuni infection

description: An infection that is caused by Campylobacter jejuni.


Small Intestinal Infection

description: An infectious process affecting the small intestine.


Duodenal Infection

description: An infectious process affecting the duodenum.


A C-glycosyl compound that is luteolin substituted by beta-D-glucopyranosyl moieties at positions 6 and 8 respectively.


(1R,2R,5S)-AH23848 hemicalcium salt

An organic calcium salt that is the hemicalcium salt of (1R,2R,5S)-AH23848.


fenoprofen calcium (anhydrous)

The anhydrous form of the calcium salt of fenprofen. The dihydrate form is used as a non-steroidal anti-inflammatory drug for the management of mild to moderate pain and for the relief of pain and inflammation associated with disorders such as arthritis.


prohexadione-calcium

A calcium salt containing equal numbers of prohexadione(2-) and Ca(2+) ions. A plant growth regulator, it is used as an anti-lodging agent in small-grain cereals.


calcium carbonate

A calcium salt with formula CCaO3.


ROSUVASTATIN CALCIUM

An organic calcium salt that is the hemicalcium salt of rosuvastatin.


PITAVASTATIN CALCIUM

The calcium salt of pitavastatin. Used for treatment of hypercholesterolemia (elevated levels of cholesterol in the blood) on patients unable to sufficiently lower their cholesterol levels by diet and exercise.


calcium gluconate

The calcium salt of D-gluconic acid.


calcium carbimide

The calcium salt of cyanamide, formed when calcium carbide reacts with nitrogen


MUPIROCIN CALCIUM

The anhydrous form of the calcium salt of mupirocin. The dihydrate form is used as an antibacterial drug for the treatment of skin infections.


calcium glucoheptonate

The calcium salt of (2xi)-D-gluco-heptonic acid. It is used as a calcium supplement for treatment of hypocalcaemia.


calcium nitrate tetrahydrate

A hydrate that is the tetrahydrate form of calcium nitrate.


LONAZOLAC CALCIUM

An organic calcium salt having [3-(4-chlorophenyl)-1-phenylpyrazol-4-yl]acetate as the counterion.


bumadizone calcium

An organic calcium salt having 2-[(1,2-diphenylhydrazino)carbonyl]hexanoate as the counterion. Used (as its hemihydrate) for treatment of rheumatoid arthritis.


calcium citrate

An organic calcium salt composed of calcium cations and citrate anions in a 3:2 ratio.


calcium chloride hexahydrate

A hydrate that is the hexahydrate form of calcium chloride.


CALCIUM STEARATE

An organic calcium salt of stearic acid. It is a component of some lubricants and surfactants.


calcium acetate

The calcium salt of acetic acid. It is used, commonly as a hydrate, to treat hyperphosphataemia (excess phosphate in the blood) in patients with kidney disease: the calcium ion combines with dietary phosphate to form (insoluble) calcium phosphate, which is excreted in the faeces.


calcium chloride dihydrate

A hydrate that is the dihydrate form of calcium chloride.


(1S,2S,5R)-AH23848 hemicalcium salt

An organic calcium salt that is the hemicalcium salt of (1S,2S,5R)-AH23848.


calcium glycerylphosphate

An organic calcium salt having glycerol 2-phosphate(2-) as the counterion.


calcium titanate

A calcium salt with the formula CaTiO3, generally obtained in the form of the mineral perovskite.


ATORVASTATIN CALCIUM

An organic calcium salt composed of calcium cations and atorvastatin anions in a 1:2 ratio.


EDTA monocalcium salt

An organic calcium salt that is the monocalcium salt of ethylenediaminetetraacetic acid (EDTA).


calcium oxalate

The calcium salt of oxalic acid, which in excess in the urine may lead to formation of oxalate calculi (kidney stones).


LEVOMEFOLATE CALCIUM

An organic calcium salt of (6S)-5-methyltetrahydrofolic acid.


calcium nitrate

Inorganic nitrate salt of calcium.


calcium oxide

A member of the class of calcium oxides of calcium and oxygen in a 1:1 ratio.


Stage IVB Rectal Cancer AJCC v8

description: Stage IVB includes: Any T, Any N, M1b. M1b: Metastasis to two or more sites or organs without peritoneal metastasis.  (AJCC 8th ed.)


hexose phosphate

A phospho sugar that is formally obtained from a hexose.


fructose 6-phosphate

A ketohexose monophosphate consisting of fructose having a phosphate group located at the 6-position.


L-sorbose 1-phosphate

The L-stereoisomer of sorbose 1-phosphate.


D-tagatofuranose 1,6-bisphosphate

The furanose form of D-tagatose 1,6-bisphosphate.


beta-D-fructofuranose 2-phosphate

The beta-anomer of D-fructofuranose 2-phosphate.


D-aldohexose 6-phosphate

Any D-aldose having a six-carbon chain with a phosphate group at C-6.


A hexose phosphate that is alpha-D-mannose phosphorylated on O-2 and O-4.


D-allose 6-phosphate

An allose phosphate consisting of D-allose having a monophosphate group at the 6-position.


D-fructose 6-phosphate

A ketohexose monophosphate that is D-fructose having a phosphate substituent at position 6. It is an important intermediate in the carbohydrate metabolism.


D-galactopyranose 1-phosphate

A D-galactose phosphate that consists of  D-galactopyranose having a single phospho substituent located at the 1-position. It is an intermediate obtained during the the galactose metabolism.


D-tagatopyranose 1-phosphate

A ketohexose monophosphate that is D-tagatopyranose in which the phosphono substituent is located at position 1.


phosphoramidon

A dipeptide isolated from the cultures of Streptomyces tanashiensis.


A mannose phosphate in which in which the phosphate group of alpha-D-mannose 1-phosphate is esterified by the alcoholic hydroxy group of L-serine.


2-deoxy-D-glucopyranose 6-phosphate

A D-hexopyranose 6-phosphate that is the 6-monophospho derivative of 2-deoxy-D-glucopyranose.


L-fuculose 1-phosphate

The 1-O-phospho derivative of L-fuculose.


D-hexose phosphate

Any mono-phosphorylated D-hexose having a chain of six carbon atoms in the molecule.


beta-D-mannosyl C30-phosphomycoketide

A mannose phosphate consisting of beta-D-mannose having a (4S,8S,12S,16S,20S)-4,8,12,16,20-pentamethylpentacosyl)phosphate group at position 1.


beta-D-mannosyl C32-phosphomycoketide

A mannose phosphate consisting of beta-D-mannose having a (4S,8S,12S,16S,20S)-4,8,12,16,20-pentamethylheptacosyl)phosphate group at position 1.


tagatose 6-phosphate

A  ketohexose monophosphate that is tagatose attached to a phosphate group at position 6.


D-fructose 1,6-bisphosphate

A ketohexose bisphosphate that is D-fructose substituted by phosphate groups at positions 1 and 6. It is an intermediate in the glycolysis metabolic pathway.


L-rhamnulose 1-phosphate

A deoxyketohexose phosphate consisting of L-rhamnulose having a monophosphate group at the 1-position.


D-galactopyranose 6-phosphate

The pyranose form of D-galactose 6-phosphate.


beta-D-mannose 6-phosphate

A D-mannopyranose 6-phosphate with a beta-configuration at the anomeric position.


A ketohexose monophosphate having keto groups at the 2- and 5-positions, hydroxy groups at the 3- and 4-positions and the phosphate group at the 6-position.


beta-D-tagatofuranose 6-phosphate

A D-tagatofuranose 6-phosphate with a beta-configuration at the anomeric position.


beta-D-glucose 6-phosphate

A D-glucopyranose 6-phosphate in which the anomeric centre has beta-configuration.


aldehydo-D-galactose 6-phosphate

The ring-opened aldehydo-form of D-galactose 6-phosphate.


alpha-D-hexose 1-phosphate

Any hexose-1-phosphate which has D configuration at position 5 and alpha-configuration at the anomeric centre.


D-mannose 6-phosphate

A mannose phosphate in which the phosphate group is attached to position 6.


D-mannose 1-phosphate

A mannose phosphate that is D-mannose carrying a phosphate group at position 1.


The alpha-anomer of D-mannose 6-phosphate.


D-glucose 6-phosphate

A D-glucose monophosphate in which the phosphate group is attached to position 6.


A fully saturated D-mannose polyisoprenoid phosphoglycolipid (C32 chain-length) obtained from Mycobacterium tuberculosis.


D-fructofuranose 2,6-bisphosphate

A ketohexose bisphosphate that is D-fructofuranose carrying phosphate groups at positions 2 and 6.


alpha-D-tagatofuranose 6-phosphate

A D-tagatofuranose 6-phosphate with an alpha-configuration at the anomeric position.


alpha-D-mannose 1-phosphate

A D-mannose 1-phosphate with an alpha-configuration at the anomeric position.


D-fructose 1-phosphate

The D-enantiomer of fructose 1-phosphate.


A fully saturated beta-D-mannose polyisoprenoid phosphoglycolipid (C27 chain-length) obtained from Mycobacterium tuberculosis.


keto-D-fructose 1,6-bisphosphate

A ketohexose bisphosphate that is D-fructose substituted by phosphate groups at positions 1 and 6.


keto-D-fructose 1-phosphate

The open chain form of D-fructose 1-phosphate.


2-deoxy-D-glucose 6-phosphate

A deoxyaldohexose phosphate comprising 2-deoxy-D-glucose having the phosphate group at the 6-position.


D-psicose 6-phosphate

A ketohexose monophosphate consisting of D-psicose having a phosphate group located at the 6-position.


A mannose phosphate that is D-mannose phosphorylated at position 6 by a N-acetyl-D-glucosaminyl-1-phosphono group. Found in the milk of giant pandas.


D-mannopyranose 6-phosphate

The pyranose form of D-mannose 6-phosphate.


A D-glucopyranose 1-phosphate in which the anomeric centre has alpha-configuration.


L-tagatofuranose 6-phosphate

The furanose form of L-tagatose 6-phosphate.


fructose 1-phosphate

A ketohexose monophosphate consisting of fructose having a phosphate group located at the 1-position


FRUCTOSE 1,6-DIPHOSPHATE

A D-fructofuranose 1,6-bisphosphate with an alpha-configuration at the anomeric position.


beta-D-glucose 1-phosphate

The beta-anomer of D-glucose 1-phosphate.


A mannose phosphate consisting of beta-D-mannose having a (4S,8S,12S,16S,20S)-4,8,12,16,20-pentamethylheptacosyl)phosphono(difluoro)methyl group at position 1.


D-tagatofuranose 6-phosphate

The furanose form of D-tagatose 6-phosphate.


D-tagatose 1,6-bisphosphate

A ketohexose bisphosphate that is D-tagatose carrying phosphate groups at positions 1 and 6.


A mannose phosphate consisting of beta-D-mannose having a (4S)-4-methylheptacosyl)phosphate group at position 1. Synthetic analogue of beta-D-mannosyl C32-phosphomycoketide.


A D-galactose 6-phosphate that is beta-D-galactofuranose in which the hydroxy group at position 6 has been converted into the corresponding dihydrogen phosphate derivative.


keto-D-tagatose 6-phosphate

A D-tagatose 6-phosphate that is in the open-chain keto-form.


A mannose phosphate consisting of beta-D-mannose having a (4S,8S,12S,16S,20S)-4,8,12,16,20-pentamethylheptacosyl)phosphonomethyl group at position 1.


alpha-D-mannosyl phosphomycoketide

A mannose phosphate consisting of alpha-D-mannose having a (4S,8S,12S,16S,20S)-4,8,12,16,20-pentamethylheptacosyl)phosphate group at position 1.


keto-L-tagatose 6-phosphate

The open chain form of L-tagatose 6-phosphate


FOSFRUCTOSE

A D-fructofuranose 1,6-bisphosphate with a beta-configuration at the anomeric position.


D-hexopyranose 6-phosphate

Any D-hexose 6-phosphate in which the hexose is in the pyranose form.


A galactose phosphate that is 4-nitrophenyl beta-D-galactoside substituted at position 6 by a monophosphate group.


beta-D-fructofuranose 1-phosphate

A D-fructofuranose 1-phosphate in which the anomeric centre has beta-configuration.


keto-D-fructose 6-phosphate

The open chain form of D-fructose 6-phosphate.


A ketohexose monophosphate that is 3-dehydro-D-glucose having the monophosphate group located at position 6.


D-glucopyranose 1-phosphate

A D-glucose monophosphate in which the phosphate group is located at position 1.


alpha-Gal glycan

An amino glycan in which an alpha-Gal-(1->3)-beta-Gal-(1->4)-GlcNAc trisaccharide unit is linked glycosidically to a polysaccharide moiety.


A glycohexaosylceramide having N-acetyl-alpha-D-galactosaminyl-(1->3)-[alpha-L-fucosyl-(1->2)]-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl component attached to the primary hydroxy function of a ceramide with d18:0 sphingoid base and undefined fatty acyl chain.


name: Cervical Mucinous Adenocarcinoma, Not Otherwise Specified

description: A cervical mucinous adenocarcinoma in which more than 50% of malignant cells contain intracytoplasmic mucin. There is no evidence of gastric, intestinal, or signet ring cell differentiation.


A derivative of toluene bearing an additional ethyl substituent at position 3.


Localized PRETEX IV Hepatoblastoma

description: PRETEX IV hepatoblastoma confined to the liver including regional lymph nodes. (Childhood cancer staging for population registries according to the Toronto Childhood Cancer Stage Guidelines - Version 2. Cancer Council Queensland and Cancer Australia: Brisbane, Australia; 2021.)


Ala-Val zwitterion

A dipeptide zwitterion resulting from the transfer of a proton from the carboxy to the amino group of Ala-Val; major species at pH 7.3.


hexan-3-yl benzoate

Hexan-3-yl ester of benzoate.


glycerolipid

Any member of the group of lipids containing a common glycerol backbone to which at least one fatty acid-derived group is attached.


A 1,2-diacyl-sn-glycero-3-phosphoethanolamine in which the acyl substituent both at positions 1 and 2 is specified as (9Z)-octadecenoyl respectively.


A 1-acyl-sn-glycerol that is the S-enantiomer of 2,3-dihydroxypropyl decanoate.


A triacyl-sn-glycerol in which the 1-acyl group is tetradecanoyl while the 2- and 3-acyl groups are oleoyl.


A 1-monolysocardiolipin in which the remaining phosphatidyl acyl groups at positions 1, 2 and 2' are specified as linoleoyl.


A triacylglycerol 62:13 in which the acyl group at position 1 is specified as octadecenoyl while those at positions 2 and 3 are both docosahexaenoyl groups.


triacylglycerol 42:0

A triglyceride in which the three acyl groups contain a total of 42 carbons and 0 double bonds.


phosphatidylserine 40:0

A 3-sn-phosphatidyl-L-serine in which the two acyl groups contain a total of 40 carbon atoms and 0 double bonds.


A glycerophosphoethanolamine that is sn-glycero-3-phosphoethanolamine bearing a single alk-1-enyl substituent at an unspecified position.


phosphatidylethanolamine

A class of glycerophospholipids in which a phosphatidyl group is esterified to the hydroxy group of ethanolamine.


A monoglyceride in which the acyl substituent is located at position 1.


A 1,2-diacyl-sn-glycero-3-phosphoethanolamine in which the acyl groups at positions 1 and 2 are both specified as hexanoyl.


GLYCERYL MONOLINOLEATE

A 1-acyl-sn-glycerol that is the S-enantiomer of 1-monolinolein.


A 2-acyl-sn-glycero-3-phosphoethanolamine in which the acyl group is specified as 4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl.


A 1,2-diacyl-sn-glycerol 3-phosphate in which the acyl group at position 1 is unspecified while that at position 2 is specified as decanoyl


glycerophosphoglycerol

A glycerophosphoglycerol where both glycerol moieties are attached at primary positions.


An N-acyl-O-(3-sn-phosphatidyl)-L-serine obtained by formal condensation of the carboxy group of hexadecanoic acid with the amino group of 1-octadecanoyl-2-oleoyl-sn-glycero-3-phospho-L-serine.


phosphatidylinositol 34:1

A 1-phosphatidyl-1D-myo-inositol in which the two acyl groups contain a total of 34 carbon atoms and 1 double bond.


triacylglycerol 52:1

A triglyceride in which the three acyl groups contain a total of 52 carbons and 1 double bond.


A 6-(alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol compound having an undefined acyl substituent in an unspecified position on the inositol ring.


A glycerol compound having an alk-1-enyl substituent in the 1-position


A 1,2-diacyl-sn-glycero-3-phosphoethanolamine in which both acyl substituents are specified as (9Z)-hexadecenoyl (palmitoleoyl).


phosphatidylethanolamine (18:1/22:4)

A phosphatidylethanolamine in which one acyl group has 18 carbons and 1 double bond while the other has 22 carbons and 4 double bonds.


A 3-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-1,2-diacyl-sn-glycerol in which the 1- and 2-acyl groups are specified as alpha-linolenoyl and hexadecanoyl respectively.


A 3-sn-phosphatidyl-L-serine in which the two phosphatidyl acyl groups are specified as lauroyl (dodecanoyl).


A 1-phosphatidyl-1D-myo-inositol in which the phosphatidyl acyl groups at positions 1 and 2 are specified as (13Z,16Z)-docosadienoyl and linoleoyl respectively.


A 1-alkyl-2-acyl-sn-glycerol 3-phosphate in which the alkyl and the acyl groups at positions 1 and 2 are specified as hexadecyl and acetyl respectively.


1-lauroyl-sn-glycerol 3-phosphate

A 1-acyl-sn-glycerol 3-phosphate having lauroyl (dodecanoyl) as the 1-O-acyl group.


A 3-sn-phosphatidyl-L-serine in which the 1- and 2-acyl groups are octadecanoyl and octadecadienoyl respectively.


TRIPALMITIN

A triglyceride obtained by formal acylation of the three hydroxy groups of glycerol by palmitic (hexadecanoic) acid.


phosphatidylethanolamine 33:1

A 1,2-diacyl-sn-glycero-3-phosphoethanolamine in which the two acyl groups contain a total of 33 carbons and 1 double bond.


phosphatidylglycerol 36:1

A phosphatidylglycerol in which the two acyl groups contain 36 carbon atoms and 1 double bond.


An N-acyllysophosphatidylethanolamine in which the N-acyl group is specified as icosanoyl while the phosphatidyl acyl group is specified as oleoyl; major species at pH 7.3.


A glycerolipid where one of the acyl groups is specified as (9Z,12Z,15Z)-octadeca-9,12,15-trien-6-ynoyl


A glycerolipid where one of the acyl groups is specified as (9Z,11E,13E)-octadecatrienoyl.


lysophosphatidylinositol 20:3

A lysophosphatidyl-1D-myo-inositol in which the remaining acyl group (position not specified) contains 20 carbons and 3 double bonds.


monoacylglycerol 16:0

A monoglyceride in which the acyl group contains a total of 16 carbon atoms and 0 double bond.


A phosphoethanolamine-glycosyl-phosphatidylinositol derivative where R1 can be an alkyl or an acyl group, R2 and R3 are both acyl groups of undefined composition.


phosphatidylserine 38:1

A 3-sn-phosphatidyl-L-serine in which the two acyl groups contain a total of 38 carbon atoms and 1 double bond.


A glycerolipid where one of the acyl groups is specified as (9Z,11E,13Z)-octadeca-9,11,13-trienoyl.


phosphatidylethanolamine 36:0

A phosphatidylethanolamine in which the two acyl groups contain a total of 36 carbons and no double bonds.


1-alpha-linolenoyl 2-acylglycerolipid

Any glycerolipid where the 1-acyl group is specified as alpha-linolenoyl.


A 1-acyl-sn-glycerol 3-phosphate in which the 1-acyl substituent is specified as decanoyl.


A galactosylglycerolipid with an alkyl group at the sn-1 position, an acyl group at the sn-2 position and a beta-D-galactosyl residue at the sn-3 position.


phosphatidylglycerol 16:0/18:1

A phosphatidylglycerol 34:1 in which the acyl group at position 1 contains 16 carbons and no double bonds while that at position 2 contains 18 carbons and 1 double bond.


A 1,2-diacyl-sn-glycerol 3-phosphate in which the acyl substituents at positions 1 and 2 are specified as oleoyl and (6Z)-octadecenoyl respectively.


A triacylglycerol 56:3 in which the acyl groups at positions 1 and 2 are specified as octadecanoyl, while that at position 3 is icosatrienoyl.


phosphatidylinositol phosphate

Any member of the phosphoinositide family of compounds, of which seven occur naturally.


A 1-(alk-1-enyl)-2-acyl-sn-glycero-3-phosphoethanolamine zwitterion in which the alk-1-enyl and acyl groups are specified as (1Z)-octadecenyl and (9Z)-octadecenoyl respectively; major species at pH 7.3.


A 1-acyl-2-tetradecanoyl-sn-glycero-3-phosphate in which the 1-acyl group is specified as hexadecanoyl (palmitoyl).


A phosphatidylethanolamine in which the phosphatidyl acyl group at C-1 and C-2 is stearoyl.


A 1-acyl-2-arachidonoyl-sn-glycero-3-phosphate in which the 1-acyl group is specified as stearoyl (octadecanoyl).


A glycerophosphoinositol resulting from partial hydrolysis of a phosphatidyl-1D-myo-inositol, which removes one of the fatty acid groups. The structure is depicted in the image where R(1) = acyl, R(2) = H or where R(1) = H, R(2) = acyl.


A 1,2-diacyl-sn-glycero-3-phosphoethanolamine in which the acyl groups at positions 1 and 2 are specified as stearoyl and linoleoyl respectively.


lysophosphatidylglycerol 18:1

A lysophosphatidylglycerol in which the acyl group (position of attachment not specified) contains 18 carbons and 1 double bond


dilauroyl phosphatidylglycerol

A phosphatidylglycerol in which the phosphatidyl acyl groups are both lauroyl.


lysophosphatidylethanolamine (18:2/0:0)

A lysophosphatidylethanolamine 18:2 in which the acyl group is located at position 1.


A phosphatidylinositol 38:3 in which one acyl group has 18 carbons and is fully saturated while the other has 20 carbons and 3 double bonds (position not specified).


monoradylglycerol

Any lipid that is glycerol bearing a single acyl, alkyl or alk-1-enyl substituent at an unspecified position.


A 1,2-diacyl-sn-glycerol 3-phosphate in which the phosphatidyl acyl groups at postions 1 and 2 are specified as heptadecanoyl and stearoyl respectively.


A 3-sn-phosphatidyl L-serine in which the phosphatidyl acyl groups at positions 1 and 2 are oleoyl and 6-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]hexanoyl respectively.


An optically active form of phosphatidylethanolamine having R-configuration.


lysophosphatidylethanolamine 20:3

An acyl-sn-glycero-3-phosphoethanolamine in which the acyl group contains twenty carbons with three double bonds and is attached to the glycero moiety at either position 1 or 2.


A glycerolipid where one of the acyl groups is specified as (5Z,8Z,11Z,14Z,17Z)-icosapentaenoyl.


A 1-phosphatidyl-1D-myo-inositol 3-phosphate in which both phosphatidyl acyl groups are specified as palmitoyl (hexadecanoyl).


An anionic lysophospholipid obtained by deprotonation of the carboxy and phosphate groups of 1-acyl-2-hydroxy-sn-glycero-3-phospho-(N-acyl)-L-serine; major species at pH 7.3.


tetraoctadec-11-enoyl cardiolipin

A cardiolipin in which all four of the phosphatidyl acyl groups are specified as octadec-11-enoyl.


phosphatidylserine 38:2

A 3-sn-phosphatidyl-L-serine in which the two acyl groups contain a total of 38 carbon atoms and 2 double bonds.


phosphatidylethanolamine (16:1/16:1)

A 1,2-diacyl-sn-glycero-3-phosphoethanolamine in which both acyl groups contain 16 carbons and 1 double bond.


lysophosphatidylserine 20:0

A lysophosphatidylserine in which the remaining acyl group (position not specified) contains 20 carbons and 0 double bonds.


phosphatidylethanolamine (16:0/20:4)

A phosphatidylethanolamine 36:4 in which the acyl group at C-1 contains 16 carbons and no double bonds while that at C-2 contains 20 carbons and 4 double bonds.


A 1-O-(alk-1-enyl)-2-octanoyl-sn-glycero-3-phosphoethanolamine zwitterion in which the alk-1-enyl group has Z geochemistry.


A 1-phosphatidyl-1D-myo-inositol in which the 1- and 2-acyl groups are octadecanoyl and octadecadienoyl respectively.


A 1,2-diacyl-sn-glycero-3-phosphoethanolamine in which the acyl substituents at positions 1 and 2 are specified as octadecanoyl (stearoyl) and (5E,8E,11E,14E)-eicosatetraenoyl respectively.


A phosphatidylethanolamine 38:4 in which one acyl group has 18 carbons and is fully saturated while the other has 20 carbons and 4 double bonds (position not specified).


A 2-monoglyceride obtained by formal condensation of the carboxy group of 14,15-EET with the 2-hydroxy group of glycerol.


phosphatidylglycerol 36:0

A phosphatidylglycerol in which the two acyl groups contain 36 carbon atoms and no double bonds


A 1,2-diacyl-sn-glycerol 3-phosphate in which the acyl group at position 1 is unspecified while that at position 2 is specified as myristoyl (tetradecanoyl).


A triacyl-sn-glycerol in which the acyl groups at positions 1 and 2 are specified as oleoyl while that at position 3 is specifed as linoleoyl.


lysophosphatidylglycerol 18:0

A lysophosphatidylglycerol in which the acyl group has a fully saturated C18 chain and is attached to the glycero moiety at either position 1 or 2.


phosphatidylserine 40:5

A 3-sn-phosphatidyl-L-serine in which the two acyl groups contain a total of 40 carbon atoms and 5 double bonds.


phosphatidylethanol

A glycerophospholipid that is the monoethyl ester of any phosphatidic acid.


An N-acyllysophosphatidylethanolamine in which the N-acyl group is specified as stearoyl (octadecanoyl) while the phosphatidyl acyl group is specified as oleoyl (9Z-octadecenoyl)


A diacylglycerolipid where the fatty acyl at sn-1 has a saturated bond between carbons 1 and 2, the glycerolipid part is unkown, R3 can be an H or a phospholipid.


A class of glycerophospholipids in which a (2S)-2,3-diacylglycerol phosphate group is esterified by condensation with the alcoholic hydroxy group of L-serine.


phosphatidylglycerol 34:3

A phosphatidylglycerol in which the two acyl groups contain 34 carbon atoms and 3 double bonds.


phosphatidylglycerol 35:1

A phosphatidylglycerol in which the two acyl groups contain a total of 35 carbon atoms and 1 double bond.


phosphatidylethanolamine (18:0/20:2)

A phosphatidylethanolamine in which one acyl group has 18 carbons and is fully saturated while the other has 20 carbons and 2 double bonds.


phosphatidylethanolamine (16:0/18:2)

1,2-diacyl-sn-glycero-3-phosphoethanolamine in which the acyl group at C-1 contains 16 carbons and no double bonds while that at C-2 contains 18 carbons and 2 double bonds.


A triglyceride where at least one of R1, R2 or R3 is a linoleoyl group. Formula is C23H36O6R2


tetrahexadecanoyl cardiolipin

A cardiolipin in which all four of the phosphatidyl acyl groups are specified as hexadecanoyl (pamitoyl).


A 1,2-diacyl-sn-glycerol 3-phosphate in which the acyl substituents at positions 1 and 2 are specified as linoleoyl and oleoyl respectively.


An N-acylphosphatidylethanolamine in which the N- and O-acyl groups are specified as hexadecanoyl (palmitoyl).


A 1,2-diacyl-sn-glycero-3-phosphate in which the acyl groups at positions 1 and 2 are specified as octanoyl.


phosphatidylglycerol 18:3/16:1

A phosphatidylglycerol 36:1 in which the acyl group at position 1 contains 18 carbons and 3 double bonds while that at position 2 contains 16 carbons and 1 double bond.


A 1-(Z-alk-1-enyl)-sn-glycero-3-phosphoethanolamine in which the Z-alk-1-enyl group is specified as (1Z)-octadec-1-enyl.


N-acyllysophosphatidyl-L-serine

An acylglycerophosphoserine obtained by formal condensation of the carboxy group of any carboxylic acid with the amino group of any lysophosphatidyl-L-serine.


phosphatidylethanolamine 40:1

A phosphatidylethanolamine in which the two acyl groups contain 40 carbon atoms and 1 double bond.


A triacylglycerol 53:2 in which the acyl groups at positions 1, 2 and 3 are specified as hexadecanoyl, octadecenoyl and nonadecenoyl respectively.


A 3-sn-phosphatidyl L-serine in which the phosphatidyl acyl groups at positions 1 and 2 are palmitoyl and stearoyl respectively.


phosphatidylglycerol O-34:4

An alkyl,acyl-sn-glycero-3-phosphoglycerol in which the alkyl or acyl groups at positions 1 and 2 contain a total of 34 carbons and 4 double bonds.


A glycerol-1-phosphate compound having an alk-1-enyl substituent at the 3-position.


A 1-alkyl-2-acetyl-3-acyl-sn-glycerol in which the alkyl and acyl groups are specified as palmityl and oleoyl.


TRICAPRILIN

A triglyceride obtained by acylation of the three hydroxy groups of glycerol by octanoic acid. Used as an alternative energy source to glucose for patients with mild to moderate Alzheimer's disease.


phosphatidylserine (17:1/18:1)

A phosphatidylserine 35:2 in which the acyl group at C-1 contains 17 carbons and 1 double bind while that at C-2 contains 18 carbons and 1 double bonds.


A 1,2-diacyl-sn-glycero-3-phosphoethanolamine in which the 1- and 2-acyl groups are specified as oleoyl and myristoyl respectively.


A triacylglycerol 62:13 in which the acyl groups at positions 1 and 2 are specified as octadecadienoyl while that at position 3 is a docosahexaenoyl group.


A glycerophosphoethanolamine that is sn-glycero-3-phosphoethanolamine carrying any alkyl substituent at position 1.


A 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) in which both acyl groups are specified as hexadecanoyl (palmitoyl).


palmitoleoyl-containing glycerolipid

A glycerolipid where one of the acyl groups is specified as palmitoleoyl.


A 1-acyl-sn-glycerol in which the acyl group is specified as oleoyl.


monoacylglycerol 22:5

A monoglyceride in which the acyl groups contain a total of 22 carbons and 5 double bonds.


A triglyceride having stearoyl (octadecanoyl) groups at positions 1 and 3 and a palmitoyl (hexadecanoyl) group at position 2. It is a metabolite of the nematode Caenorhabditis elegans.


A CDP-diacylglycerol in which the phosphatidyl acyl groups at positions 1 and 2 are specified as stearoyl and oleoyl respectively.


A 3-sn-phosphatidyl-L-serine in which the 1- and 2-acyl groups are octadecenoyl groups.


glycerophosphomethanol

The glycerol phosphate ester of a phosphomethanol.


A 1,2-diacyl-sn-glycerol 3-phosphate in which the phosphatidyl acyl groups at postions 1 and 2 are specified as heptadecanoyl and palmitoyl respectively.


phosphatidylethanolamine (17:1/17:1)

A 1,2-diacyl-sn-glycero-3-phosphoethanolamine in which both acyl groups contain 17 carbons and 1 double bond.


A 1,2-diacyl-sn-glycerol 3-phosphate in which the acyl group at position 1 is unspecified while that at position 2 is specified as palmitoyl (hexadecanoyl).


A 1-(alk-1-enyl)-2-acyl-sn-glycero-3-phosphate in which the alk-1-enyl and acyl groups are specified as (1Z)-octadecenyl and oleoyl respectively.


A CDP-diacylglycerol in which the phosphatidyl acyl groups at positions 1 and 2 are specified as stearoyl and arachidonoyl respectively.


A 1,2-diacyl-sn-glycero-3-phosphoethanolamine in which the 1- and 2-acyl groups are specified as myristoyl and oleoyl respectively.