name: IFNG signaling activates MAPKs (Rattus norvegicus)


name: JAK1-activated RAF1 phosphorylates MAPKs (Rattus norvegicus)

category: biolink:MolecularActivity biolink:Occurrent biolink:OntologyClass biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent


name: JAK1-mediated phosphorylation of RAF1 (Rattus norvegicus)


name: Activated JAK1 binds RAF1 (Rattus norvegicus)


name: IFNG signaling activates MAPKs (Canis familiaris)

category: biolink:Pathway biolink:OntologyClass biolink:BiologicalProcess biolink:Occurrent biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent


name: JAK1-activated RAF1 phosphorylates MAPKs (Canis familiaris)


name: Activated JAK1 binds RAF1 (Canis familiaris)


name: JAK1-mediated phosphorylation of RAF1 (Canis familiaris)


name: IFNG signaling activates MAPKs (Bos taurus)


name: JAK1-mediated phosphorylation of RAF1 (Bos taurus)


name: JAK1-activated RAF1 phosphorylates MAPKs (Bos taurus)


name: IFNG signaling activates MAPKs (Sus scrofa)


name: JAK1-mediated phosphorylation of RAF1 (Sus scrofa)


name: JAK1-activated RAF1 phosphorylates MAPKs (Sus scrofa)


name: IFNG signaling activates MAPKs (Gallus gallus)


name: JAK1-activated RAF1 phosphorylates MAPKs (Gallus gallus)


name: JAK1-mediated phosphorylation of RAF1 (Gallus gallus)


name: Activated JAK1 binds RAF1 (Gallus gallus)


name: Interferon gamma signaling (Homo sapiens)


name: Phosphorylation of STAT1 at Ser727 (Homo sapiens)


name: Transphosphorylation of JAK1 (Homo sapiens)


name: IFNGR1:JAK1:INFGR2:JAK2 binds JAK1,2 inhibitors (Homo sapiens)

definition: Inhibition


name: Translocation of STAT1 dimer to nucleus (Homo sapiens)


name: Phosphorylated YBX1 translocates to the nucleus (Homo sapiens)


name: Phosphorylation of STAT1 by JAK kinases (Homo sapiens)


name: GAF binds the GAS promoter elements in the IFNG-regulated genes (Homo sapiens)


name: Binding of STAT1 to p-IFNGR1 (Homo sapiens)


name: Expression of IFNG-stimulated genes (Homo sapiens)


name: Release of STAT1 dimer from active receptor unit (Homo sapiens)


name: Phosphorylation of IFNGR1 by JAK kinases (Homo sapiens)


name: JAK2-activated MAPKs phosphorylate YBX1 (Homo sapiens)


name: IFNG dimer binds IFNG inhibitors (Homo sapiens)


name: Interferon gamma signaling (Rattus norvegicus)


name: Transphosphorylation of JAK1 (Rattus norvegicus)


name: Phosphorylated YBX1 translocates to the nucleus (Rattus norvegicus)


name: IFNG dimer binds IFNGR (Rattus norvegicus)


name: Phosphorylation of IFNGR1 by JAK kinases (Rattus norvegicus)


name: Phosphorylation of STAT1 by JAK kinases (Rattus norvegicus)


name: IFNG dimer binds IFNG inhibitors (Rattus norvegicus)


name: Translocation of STAT1 dimer to nucleus (Rattus norvegicus)


name: Phosphorylation of JAK2 (Rattus norvegicus)


name: Release of STAT1 dimer from active receptor unit (Rattus norvegicus)


name: Phosphorylation of STAT1 at Ser727 (Rattus norvegicus)


name: Binding of STAT1 to p-IFNGR1 (Rattus norvegicus)


name: IFNGR1:JAK1:INFGR2:JAK2 binds JAK1,2 inhibitors (Rattus norvegicus)


name: JAK2-activated MAPKs phosphorylate YBX1 (Rattus norvegicus)


name: Interferon gamma signaling (Canis familiaris)


name: JAK2-activated MAPKs phosphorylate YBX1 (Canis familiaris)


name: Phosphorylation of JAK2 (Canis familiaris)


name: Release of STAT1 dimer from active receptor unit (Canis familiaris)


name: Phosphorylation of IFNGR1 by JAK kinases (Canis familiaris)


name: IFNG dimer binds IFNGR (Canis familiaris)


name: Phosphorylated YBX1 translocates to the nucleus (Canis familiaris)


name: IFNG dimer binds IFNG inhibitors (Canis familiaris)


name: Binding of STAT1 to p-IFNGR1 (Canis familiaris)


name: Translocation of STAT1 dimer to nucleus (Canis familiaris)


name: Phosphorylation of STAT1 at Ser727 (Canis familiaris)


name: IFNGR1:JAK1:INFGR2:JAK2 binds JAK1,2 inhibitors (Canis familiaris)


name: Phosphorylation of STAT1 by JAK kinases (Canis familiaris)


name: Transphosphorylation of JAK1 (Canis familiaris)


name: Translocation of STAT1 dimer to nucleus (Bos taurus)


name: Binding of STAT1 to p-IFNGR1 (Bos taurus)


name: Transphosphorylation of JAK1 (Bos taurus)


name: Phosphorylation of STAT1 by JAK kinases (Bos taurus)


name: IFNGR1:JAK1:INFGR2:JAK2 binds JAK1,2 inhibitors (Bos taurus)


name: Phosphorylation of IFNGR1 by JAK kinases (Bos taurus)


name: Release of STAT1 dimer from active receptor unit (Bos taurus)


name: IFNG dimer binds IFNG inhibitors (Bos taurus)


name: JAK2-activated MAPKs phosphorylate YBX1 (Bos taurus)


name: Phosphorylation of STAT1 at Ser727 (Bos taurus)


name: Phosphorylated YBX1 translocates to the nucleus (Bos taurus)


name: Phosphorylation of STAT1 at Ser727 (Sus scrofa)


name: IFNG dimer binds IFNG inhibitors (Sus scrofa)


name: IFNGR1:JAK1:INFGR2:JAK2 binds JAK1,2 inhibitors (Sus scrofa)


name: Translocation of STAT1 dimer to nucleus (Sus scrofa)


name: Binding of STAT1 to p-IFNGR1 (Sus scrofa)


name: JAK2-activated MAPKs phosphorylate YBX1 (Sus scrofa)


name: Transphosphorylation of JAK1 (Sus scrofa)


name: Phosphorylated YBX1 translocates to the nucleus (Sus scrofa)


name: Phosphorylation of STAT1 by JAK kinases (Sus scrofa)


name: Phosphorylation of IFNGR1 by JAK kinases (Sus scrofa)


name: Release of STAT1 dimer from active receptor unit (Sus scrofa)


name: Interferon gamma signaling (Danio rerio)


name: Binding of STAT1 to p-IFNGR1 (Danio rerio)


name: JAK2-activated MAPKs phosphorylate YBX1 (Danio rerio)


name: Phosphorylation of STAT1 at Ser727 (Danio rerio)


name: IFNGR1:JAK1:INFGR2:JAK2 binds JAK1,2 inhibitors (Danio rerio)


name: IFNG dimer binds IFNG inhibitors (Danio rerio)


name: Release of STAT1 dimer from active receptor unit (Danio rerio)


name: Translocation of STAT1 dimer to nucleus (Danio rerio)


name: Phosphorylation of IFNGR1 by JAK kinases (Danio rerio)


name: Phosphorylation of STAT1 by JAK kinases (Danio rerio)


name: Transphosphorylation of JAK1 (Danio rerio)


name: Phosphorylated YBX1 translocates to the nucleus (Danio rerio)


name: Interferon gamma signaling (Xenopus tropicalis)


name: Phosphorylated YBX1 translocates to the nucleus (Xenopus tropicalis)


name: JAK2-activated MAPKs phosphorylate YBX1 (Xenopus tropicalis)


name: Translocation of STAT1 dimer to nucleus (Xenopus tropicalis)


name: IFNGR1:JAK1:INFGR2:JAK2 binds JAK1,2 inhibitors (Xenopus tropicalis)


name: Interferon gamma signaling (Gallus gallus)


name: IFNGR1:JAK1:INFGR2:JAK2 binds JAK1,2 inhibitors (Gallus gallus)


name: Phosphorylation of STAT1 by JAK kinases (Gallus gallus)


name: Phosphorylation of IFNGR1 by JAK kinases (Gallus gallus)


name: IFNG dimer binds IFNG inhibitors (Gallus gallus)


name: Transphosphorylation of JAK1 (Gallus gallus)


name: Binding of STAT1 to p-IFNGR1 (Gallus gallus)


name: Phosphorylated YBX1 translocates to the nucleus (Gallus gallus)


name: Translocation of STAT1 dimer to nucleus (Gallus gallus)


name: JAK2-activated MAPKs phosphorylate YBX1 (Gallus gallus)


name: Release of STAT1 dimer from active receptor unit (Gallus gallus)


name: Phosphorylation of STAT1 at Ser727 (Gallus gallus)


name: Interferon gamma signaling (Drosophila melanogaster)


name: JAK2-activated MAPKs phosphorylate YBX1 (Drosophila melanogaster)


name: Translocation of STAT1 dimer to nucleus (Drosophila melanogaster)


name: Phosphorylated YBX1 translocates to the nucleus (Drosophila melanogaster)


name: Interferon gamma signaling (Caenorhabditis elegans)


name: Translocation of STAT1 dimer to nucleus (Caenorhabditis elegans)


name: JAK2-activated MAPKs phosphorylate YBX1 (Caenorhabditis elegans)


name: Phosphorylated YBX1 translocates to the nucleus (Caenorhabditis elegans)


name: Interferon gamma signaling (Dictyostelium discoideum)


name: Translocation of STAT1 dimer to nucleus (Dictyostelium discoideum)


name: SARS-CoV-2 modulates host translation machinery (Homo sapiens)


name: SARS-CoV-2 nsp9 binds to 7SL RNA (Homo sapiens)


name: SARS-CoV-2 nsp1 binds to 40S ribosomal complex (Homo sapiens)


name: SARS-CoV-2 nsp16 binds to U2 snRNA (Homo sapiens)


name: SARS-CoV-2 nsp16 binds to U1 snRNA (Homo sapiens)


name: SARS-CoV-2 nsp8 binds to 7SL RNA (Homo sapiens)


name: SARS-CoV-2 activates/modulates innate and adaptive immune responses (Homo sapiens)


name: SARS-CoV-2 8 binds IL17RA (Homo sapiens)


name: SARS-CoV-2 9b binds IKBKG (Homo sapiens)


name: MAVS:TOMM70 recruits HSP90:TBK1:IRF3 (Homo sapiens)


name: IL17RA and IL17RC bind IL17A dimer,IL17F dimer,IL17A:IL17F (Homo sapiens)


name: CNBP binds SARS-CoV-2 G-rich RNA (Homo sapiens)


name: SARS-CoV-2 N binds to TRIM25 (Homo sapiens)


name: SARS-CoV-2 S binds SFTPD 12mer (Homo sapiens)


name: SARS-CoV-2 9b binds TOMM70 (Homo sapiens)


name: SARS-CoV-2 8:class I MHC binds BECN1 (Homo sapiens)


name: SARS-CoV-2 3a induces potassium efflux (Homo sapiens)


name: SARS-CoV-2 6 binds NUP98:RAE1 within NPC (Homo sapiens)


name: Capturing cargo and formation of prebudding complex (Homo sapiens)


name: SARS-CoV-2 3CLpro dimer binds to STING (Homo sapiens)


name: SARS-CoV-2 M protein binds MAVS (Homo sapiens)


name: SARS-CoV-2 8 binds class I MHC (Homo sapiens)


name: SARS-CoV-2 nsp3 cleaves IRF3 (Homo sapiens)


name: SARS-CoV-2 3CLpro dimer cleaves NLRP12 (Homo sapiens)


name: TLR8 dimer binds SARS-CoV-2 GU-rich ssRNA  (Homo sapiens)


name: CREBBP acetylates SARS-CoV-2 N at K375 (Homo sapiens)


name: Dimerized phospho-IRF3, IRF7 is transported to the nucleus (Homo sapiens)


name: SARS-CoV-2 N binds to G3BP1,G3BP2 (Homo sapiens)


name: DDX58 is K63 polyubiquitinated (Homo sapiens)


name: TBK1/IKK epsilon complex interacts with MAVS bound TRAF3 (Homo sapiens)


name: C-ter TLR7 dimer binds SARS-CoV-2 GU-rich ssRNA (Homo sapiens)


name: SARS-CoV-2 nsp6 binds TBK1 (Homo sapiens)


name: SARS-CoV-2 nsp3 deISGylates ISGylated IRF3 (Homo sapiens)


name: LARP1 binds SARS-CoV-2 RNA (Homo sapiens)


name: SARS-CoV-2 E pentamer transports Ca2+  (Homo sapiens)


name: IFIH1:TKFC binds SARS-CoV-2 dsRNA intermediates  (Homo sapiens)


name: DDX58 binds SARS-CoV-2 dsRNA intermediates (Homo sapiens)


name: SARS-CoV-2 nsp13 binds TBK1 (Homo sapiens)


name: SARS-CoV-2 3a binds to STING (Homo sapiens)


name: SARS-CoV-2 nsp3 deISGylates ISGylated IFIH1 (Homo sapiens)


name: Activated TAK1 mediates phosphorylation of the IKK Complex (Homo sapiens)


name: SARS-CoV-2 N protein binds STAT1, STAT2 (Homo sapiens)


name: TLR2:TLR1 binds SARS-CoV-2 E pentamer (Homo sapiens)


name: TBK1, IKBKE are autophosphorylated at Ser172 (Homo sapiens)


name: SARS-CoV-2 3CLpro dimer cleaves TAB1 (Homo sapiens)


name: SARS-CoV-2 modulates autophagy (Homo sapiens)


name: SARS-CoV-2 M protein binds TUFM (Homo sapiens)


name: SARS-COV 7a translocates to the late endosome membrane (Homo sapiens)


name: SARS-CoV-2 3a tetramer binds to VPS39 within HOPS complex (Homo sapiens)


name: SARS-CoV-2 3a binds to UVRAG (Homo sapiens)


name: SARS-CoV-2 M protein binds MAP1LC3B (Homo sapiens)


name: SARS-CoV-2 targets host intracellular signalling and regulatory pathways (Homo sapiens)


name: PDPK1 phosphorylates AKT at T308 (Homo sapiens)


name: SARS-CoV-2 N binds to 14-3-3 proteins (Homo sapiens)


name: SARS-CoV-2 M, N bind to PDPK1 (Homo sapiens)


name: SARS-CoV-2 3a tetramer binds to CAV1 (Homo sapiens)


name: SARS-CoV-2 targets PDZ proteins in cell-cell junction (Homo sapiens)


name: Association of Cx43 with TJP1 (Homo sapiens)


name: MPP5 binds SARS-CoV-2 E pentamer (Homo sapiens)


name: Crumbs forms a ternary complex with Pals1 and PATJ at tight junctions (Homo sapiens)


name: SARS-CoV-2 E pentamer binds TJP1 (Homo sapiens)


name: Regulation of gap junction activity (Homo sapiens)


name: Phosphorylation of Cx43 by c-src (Homo sapiens)


name: c-src associates with Cx43 in gap junctions (Homo sapiens)


name: Regulation of gap junction activity (Mus musculus)


name: c-src associates with Cx43 in gap junctions (Mus musculus)


name: Phosphorylation of Cx43 by c-src (Mus musculus)


name: Regulation of gap junction activity (Rattus norvegicus)


name: Closure of gap junction (Rattus norvegicus)


name: c-src associates with Cx43 in gap junctions (Rattus norvegicus)


name: Phosphorylation of Cx43 by c-src (Rattus norvegicus)


name: Regulation of gap junction activity (Canis familiaris)


name: Phosphorylation of Cx43 by c-src (Canis familiaris)


name: Closure of gap junction (Canis familiaris)


name: c-src associates with Cx43 in gap junctions (Canis familiaris)


name: Regulation of gap junction activity (Bos taurus)


name: c-src associates with Cx43 in gap junctions (Bos taurus)


name: Phosphorylation of Cx43 by c-src (Bos taurus)


name: Regulation of gap junction activity (Sus scrofa)


name: Phosphorylation of Cx43 by c-src (Sus scrofa)


name: c-src associates with Cx43 in gap junctions (Sus scrofa)


name: Regulation of gap junction activity (Danio rerio)


name: Regulation of gap junction activity (Gallus gallus)


name: Phosphorylation of Cx43 by c-src (Gallus gallus)


name: c-src associates with Cx43 in gap junctions (Gallus gallus)


name: Lysosomal degradation of gap junction plaques (Homo sapiens)


name: Internalization of gap junction plaques (Homo sapiens)


name: Formation of annular gap junctions (Homo sapiens)


name: Dab2 is recruited to the junctional plaques (Homo sapiens)


name: Dynamin is recruited to the gap junction plaque (Homo sapiens)


name: Formation of annular gap junctions (Mus musculus)


name: Dynamin is recruited to the gap junction plaque (Mus musculus)


name: Dab2 is recruited to the junctional plaques (Mus musculus)


name: Formation of annular gap junctions (Rattus norvegicus)


name: Dab2 is recruited to the junctional plaques (Rattus norvegicus)


name: Dynamin is recruited to the gap junction plaque (Rattus norvegicus)


name: Formation of annular gap junctions (Canis familiaris)


name: Dynamin is recruited to the gap junction plaque (Canis familiaris)


name: Dab2 is recruited to the junctional plaques (Canis familiaris)


name: Formation of annular gap junctions (Bos taurus)


name: Dab2 is recruited to the junctional plaques (Bos taurus)


name: Dynamin is recruited to the gap junction plaque (Bos taurus)


name: Formation of annular gap junctions (Sus scrofa)


name: Dynamin is recruited to the gap junction plaque (Sus scrofa)


name: Dab2 is recruited to the junctional plaques (Sus scrofa)


name: Formation of annular gap junctions (Xenopus tropicalis)


name: Dab2 is recruited to the junctional plaques (Xenopus tropicalis)


name: Formation of annular gap junctions (Gallus gallus)


name: Dab2 is recruited to the junctional plaques (Gallus gallus)


name: Dynamin is recruited to the gap junction plaque (Gallus gallus)


name: Formation of annular gap junctions (Drosophila melanogaster)


name: Dynamin is recruited to the gap junction plaque (Drosophila melanogaster)


name: Formation of annular gap junctions (Caenorhabditis elegans)


name: Dynamin is recruited to the gap junction plaque (Caenorhabditis elegans)


gap junction assembly

category: biolink:BiologicalProcess biolink:Occurrent biolink:OntologyClass biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: Assembly of gap junctions, which are found in most animal tissues, and serve as direct connections between the cytoplasms of adjacent cells. They provide open channels through the plasma membrane, allowing ions and small molecules (less than approximately a thousand daltons) to diffuse freely between neighboring cells, but preventing the passage of proteins and nucleic acids.


name: Insertion of connexons into the plasma membrane resulting in the formation of hemi-channels (Homo sapiens)


name: Docking of connexons into junctional, double-membrane spanning channels (Homo sapiens)


name: Connexin synthesis (generic) (Homo sapiens)


name: Formation of junctional channels (Homo sapiens)


name: Assembly of gap junction plaques (Homo sapiens)


name: Oligomerization of connexins into connexons (Homo sapiens)


name: Connexin oligomerization in  ER-Golgi-Intermediate Compartment (Homo sapiens)


name: Connexin oligomerization in endoplasmic reticulum membrane (Homo sapiens)


name: Connexin oligomerization in Trans-Golgi Network (TGN) (Homo sapiens)


name: Oligomerization of connexins into connexons (Mus musculus)


name: Connexin oligomerization in endoplasmic reticulum membrane (Mus musculus)


name: Oligomerization of connexins into connexons (Rattus norvegicus)


name: Connexin oligomerization in endoplasmic reticulum membrane (Rattus norvegicus)


name: Oligomerization of connexins into connexons (Canis familiaris)


name: Connexin oligomerization in endoplasmic reticulum membrane (Canis familiaris)


name: Oligomerization of connexins into connexons (Bos taurus)


name: Connexin oligomerization in endoplasmic reticulum membrane (Bos taurus)


name: Oligomerization of connexins into connexons (Sus scrofa)


name: Connexin oligomerization in endoplasmic reticulum membrane (Sus scrofa)


name: Oligomerization of connexins into connexons (Danio rerio)


name: Connexin oligomerization in endoplasmic reticulum membrane (Danio rerio)


name: Oligomerization of connexins into connexons (Xenopus tropicalis)


name: Connexin oligomerization in endoplasmic reticulum membrane (Xenopus tropicalis)


name: Oligomerization of connexins into connexons (Gallus gallus)


name: Connexin oligomerization in endoplasmic reticulum membrane (Gallus gallus)


name: Transport of connexins along the secretory pathway (Homo sapiens)


name: Transport of connexins to the Trans-Golgi Network (TGN) (Homo sapiens)


name: Transport of connexins to the ER-Golgi intermediate compartment (Homo sapiens)


name: Transport of connexons to the plasma membrane (Homo sapiens)


name: Microtubule-independent trafficking of connexons to the plasma membrane (Homo sapiens)


name: Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane (Homo sapiens)


name: Budding of connexon-containing transport vesicles from the Golgi (Homo sapiens)


name: Association of Golgi  transport vesicles with microtubules (Homo sapiens)


name: Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane (Mus musculus)


name: Budding of connexon-containing transport vesicles from the Golgi (Mus musculus)


name: Association of Golgi  transport vesicles with microtubules (Mus musculus)


name: Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane (Rattus norvegicus)


name: Association of Golgi  transport vesicles with microtubules (Rattus norvegicus)


name: Budding of connexon-containing transport vesicles from the Golgi (Rattus norvegicus)


name: Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane (Canis familiaris)


name: Association of Golgi  transport vesicles with microtubules (Canis familiaris)


name: Budding of connexon-containing transport vesicles from the Golgi (Canis familiaris)


name: Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane (Bos taurus)


name: Association of Golgi  transport vesicles with microtubules (Bos taurus)


name: Budding of connexon-containing transport vesicles from the Golgi (Bos taurus)


name: Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane (Sus scrofa)


name: Association of Golgi  transport vesicles with microtubules (Sus scrofa)


name: Budding of connexon-containing transport vesicles from the Golgi (Sus scrofa)


name: Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane (Danio rerio)


name: Budding of connexon-containing transport vesicles from the Golgi (Danio rerio)


name: Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane (Xenopus tropicalis)


name: Budding of connexon-containing transport vesicles from the Golgi (Xenopus tropicalis)


name: Association of Golgi  transport vesicles with microtubules (Xenopus tropicalis)


name: Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane (Gallus gallus)


name: Budding of connexon-containing transport vesicles from the Golgi (Gallus gallus)


name: Transport of connexons to the plasma membrane (Mus musculus)


name: Microtubule-independent trafficking of connexons to the plasma membrane (Mus musculus)


name: Transport of connexons to the plasma membrane (Rattus norvegicus)


name: Microtubule-independent trafficking of connexons to the plasma membrane (Rattus norvegicus)


name: Transport of connexons to the plasma membrane (Canis familiaris)


name: Microtubule-independent trafficking of connexons to the plasma membrane (Canis familiaris)


name: Transport of connexons to the plasma membrane (Bos taurus)


name: Microtubule-independent trafficking of connexons to the plasma membrane (Bos taurus)


name: Transport of connexons to the plasma membrane (Sus scrofa)


name: Microtubule-independent trafficking of connexons to the plasma membrane (Sus scrofa)


name: Transport of connexons to the plasma membrane (Danio rerio)


name: Microtubule-independent trafficking of connexons to the plasma membrane (Danio rerio)


name: Transport of connexons to the plasma membrane (Xenopus tropicalis)


name: Microtubule-independent trafficking of connexons to the plasma membrane (Xenopus tropicalis)


name: Transport of connexons to the plasma membrane (Gallus gallus)


name: Microtubule-independent trafficking of connexons to the plasma membrane (Gallus gallus)


name: Connexin synthesis (generic) (Mus musculus)


name: Connexin synthesis (generic) (Rattus norvegicus)


name: Connexin synthesis (generic) (Canis familiaris)


name: Connexin synthesis (generic) (Bos taurus)


name: Connexin synthesis (generic) (Sus scrofa)


name: Connexin synthesis (generic) (Xenopus tropicalis)


name: Connexin synthesis (generic) (Gallus gallus)


name: Internalization of gap junction plaques (Mus musculus)


name: Lysosomal degradation of gap junction plaques (Mus musculus)


name: Gap junction degradation (Rattus norvegicus)


name: Internalization of gap junction plaques (Rattus norvegicus)


name: Lysosomal degradation of gap junction plaques (Rattus norvegicus)


name: Gap junction degradation (Canis familiaris)


name: Lysosomal degradation of gap junction plaques (Canis familiaris)


name: Internalization of gap junction plaques (Canis familiaris)


name: Internalization of gap junction plaques (Bos taurus)


name: Lysosomal degradation of gap junction plaques (Bos taurus)


name: Internalization of gap junction plaques (Sus scrofa)


name: Lysosomal degradation of gap junction plaques (Sus scrofa)


name: Gap junction degradation (Gallus gallus)


name: Lysosomal degradation of gap junction plaques (Gallus gallus)


name: Internalization of gap junction plaques (Gallus gallus)


name: Gap junction degradation (Drosophila melanogaster)


name: Lysosomal degradation of gap junction plaques (Drosophila melanogaster)


name: Internalization of gap junction plaques (Drosophila melanogaster)


name: Gap junction degradation (Caenorhabditis elegans)


name: Internalization of gap junction plaques (Caenorhabditis elegans)


name: Lysosomal degradation of gap junction plaques (Caenorhabditis elegans)


name: Formation of classic pathway C5 convertase (Homo sapiens)


name: Cleavage of C3 by C3 convertases (Homo sapiens)


name: Cleavage of C3 by C3 convertases (Mus musculus)


name: Formation of classic pathway C5 convertase (Mus musculus)


name: Activation of C3 and C5 (Rattus norvegicus)


name: Formation of classic pathway C5 convertase (Rattus norvegicus)


name: Cleavage of C3 by C3 convertases (Rattus norvegicus)


name: C5 binds C5 inhibitors (Rattus norvegicus)


name: Activation of C3 and C5 (Canis familiaris)


name: Cleavage of C3 by C3 convertases (Canis familiaris)


name: Formation of classic pathway C5 convertase (Canis familiaris)


name: C5 binds C5 inhibitors (Canis familiaris)


name: Cleavage of C3 by C3 convertases (Bos taurus)


name: Formation of classic pathway C5 convertase (Bos taurus)


name: Cleavage of C3 by C3 convertases (Sus scrofa)


name: Formation of classic pathway C5 convertase (Sus scrofa)


name: Cleavage of C3 by C3 convertases (Danio rerio)


name: Activation of C3 and C5 (Xenopus tropicalis)


name: Formation of classic pathway C5 convertase (Xenopus tropicalis)


name: Cleavage of C3 by C3 convertases (Xenopus tropicalis)


name: Formation of classic pathway C5 convertase (Gallus gallus)


name: Cleavage of C3 by C3 convertases (Gallus gallus)


name: Initial triggering of complement (Homo sapiens)


name: C4b binds to cell surface (Homo sapiens)


name: Conversion of C2 into C2a and C2b (Homo sapiens)


name: Formation of Classical C3 convertase (C4b:C2a complex) (Homo sapiens)


name: Conversion of C4 into C4a and C4b (Homo sapiens)


name: Lectin pathway of complement activation (Homo sapiens)


name: CL-LK binds carbohydrates on target cell surface (Homo sapiens)


name: MBL binds to repetitive carbohydrate structures on the surfaces of viruses, bacteria, fungi, and protozoa (Homo sapiens)


name: Ficolins bind to repetitive carbohydrate structures on the target cell surface (Homo sapiens)


name: Ficolin-3 binds to molecular patterns on the target cell surface  (Homo sapiens)


name: Ficolin-1 binds to molecular patterns on the target cell surface (Homo sapiens)


name: Ficolin-2 binds to molecular patterns on the target cell surface  (Homo sapiens)


name: Ficolins bind to repetitive carbohydrate structures on the target cell surface (Mus musculus)


name: Ficolin-1 binds to molecular patterns on the target cell surface (Mus musculus)


name: Ficolin-2 binds to molecular patterns on the target cell surface  (Mus musculus)


name: Ficolins bind to repetitive carbohydrate structures on the target cell surface (Rattus norvegicus)


name: Ficolin-2 binds to molecular patterns on the target cell surface  (Rattus norvegicus)


name: Ficolin-1 binds to molecular patterns on the target cell surface (Rattus norvegicus)


name: Ficolins bind to repetitive carbohydrate structures on the target cell surface (Canis familiaris)


name: Ficolin-1 binds to molecular patterns on the target cell surface (Canis familiaris)


name: Ficolin-2 binds to molecular patterns on the target cell surface  (Canis familiaris)


name: Ficolins bind to repetitive carbohydrate structures on the target cell surface (Bos taurus)


name: Ficolin-1 binds to molecular patterns on the target cell surface (Bos taurus)


name: Ficolin-2 binds to molecular patterns on the target cell surface  (Bos taurus)


name: Ficolins bind to repetitive carbohydrate structures on the target cell surface (Sus scrofa)


name: Ficolin-1 binds to molecular patterns on the target cell surface (Sus scrofa)


name: Ficolin-2 binds to molecular patterns on the target cell surface  (Sus scrofa)


name: Ficolins bind to repetitive carbohydrate structures on the target cell surface (Xenopus tropicalis)


name: Ficolin-2 binds to molecular patterns on the target cell surface  (Xenopus tropicalis)


name: Ficolin-1 binds to molecular patterns on the target cell surface (Xenopus tropicalis)


name: Ficolins bind to repetitive carbohydrate structures on the target cell surface (Gallus gallus)


name: Ficolin-1 binds to molecular patterns on the target cell surface (Gallus gallus)


name: Ficolin-2 binds to molecular patterns on the target cell surface  (Gallus gallus)


name: Lectin pathway of complement activation (Mus musculus)


name: CL-LK binds carbohydrates on target cell surface (Mus musculus)


name: MBL binds to repetitive carbohydrate structures on the surfaces of viruses, bacteria, fungi, and protozoa (Mus musculus)


name: Lectin pathway of complement activation (Rattus norvegicus)


name: MBL binds to repetitive carbohydrate structures on the surfaces of viruses, bacteria, fungi, and protozoa (Rattus norvegicus)


name: CL-LK binds carbohydrates on target cell surface (Rattus norvegicus)


name: Lectin pathway of complement activation (Canis familiaris)


name: CL-LK binds carbohydrates on target cell surface (Canis familiaris)


name: Lectin pathway of complement activation (Bos taurus)


name: MBL binds to repetitive carbohydrate structures on the surfaces of viruses, bacteria, fungi, and protozoa (Bos taurus)


name: CL-LK binds carbohydrates on target cell surface (Bos taurus)


name: Lectin pathway of complement activation (Sus scrofa)


name: MBL binds to repetitive carbohydrate structures on the surfaces of viruses, bacteria, fungi, and protozoa (Sus scrofa)


name: CL-LK binds carbohydrates on target cell surface (Sus scrofa)


name: Lectin pathway of complement activation (Xenopus tropicalis)


name: Activation of MASPs (Xenopus tropicalis)


name: Lectin pathway of complement activation (Gallus gallus)


name: CL-LK binds carbohydrates on target cell surface (Gallus gallus)


name: MBL binds to repetitive carbohydrate structures on the surfaces of viruses, bacteria, fungi, and protozoa (Gallus gallus)


name: Classical antibody-mediated complement activation (Homo sapiens)


name: Classical antibody-mediated complement activation (Mus musculus)


name: Classical antibody-mediated complement activation (Rattus norvegicus)


name: Classical antibody-mediated complement activation (Canis familiaris)


name: Classical antibody-mediated complement activation (Bos taurus)


name: Classical antibody-mediated complement activation (Sus scrofa)


name: Classical antibody-mediated complement activation (Gallus gallus)


name: Alternative complement activation (Homo sapiens)


name: Factor B binds to C3(H2O) (Homo sapiens)


name: C3b binds to cell surface (Homo sapiens)


name: Spontaneous hydrolysis of C3 thioester (Homo sapiens)


name: Properdin stabilizes C3b:Bb bound to cell surfaces (Homo sapiens)


name: C3(H2O):Factor Bb cleaves C3 to C3b and C3a (Homo sapiens)


name: Formation of alternative pathway C5 convertase (Homo sapiens)


name: Factor B binds to surface-associated C3b (Homo sapiens)


name: Factor D cleaves C3(H2O)-bound Factor B (Homo sapiens)


name: Factor D cleaves C3b-bound Factor B (Homo sapiens)


name: Alternative complement activation (Mus musculus)


name: C3(H2O):Factor Bb cleaves C3 to C3b and C3a (Mus musculus)


name: Factor D cleaves C3(H2O)-bound Factor B (Mus musculus)


name: Formation of alternative pathway C5 convertase (Mus musculus)


name: Factor B binds to C3(H2O) (Mus musculus)


name: Properdin stabilizes C3b:Bb bound to cell surfaces (Mus musculus)


name: Factor D cleaves C3b-bound Factor B (Mus musculus)


name: Factor B binds to surface-associated C3b (Mus musculus)


name: C3b binds to cell surface (Mus musculus)


name: Spontaneous hydrolysis of C3 thioester (Mus musculus)


name: Alternative complement activation (Rattus norvegicus)


name: Spontaneous hydrolysis of C3 thioester (Rattus norvegicus)


name: C3b binds to cell surface (Rattus norvegicus)


name: Alternative complement activation (Canis familiaris)


name: Properdin stabilizes C3b:Bb bound to cell surfaces (Canis familiaris)


name: C3b binds to cell surface (Canis familiaris)


name: Factor D cleaves C3(H2O)-bound Factor B (Canis familiaris)


name: Formation of alternative pathway C5 convertase (Canis familiaris)


name: Spontaneous hydrolysis of C3 thioester (Canis familiaris)


name: C3(H2O):Factor Bb cleaves C3 to C3b and C3a (Canis familiaris)


name: Factor D cleaves C3b-bound Factor B (Canis familiaris)


name: Factor B binds to C3(H2O) (Canis familiaris)


name: Factor B binds to surface-associated C3b (Canis familiaris)


name: Alternative complement activation (Bos taurus)


name: Formation of alternative pathway C5 convertase (Bos taurus)


name: Properdin stabilizes C3b:Bb bound to cell surfaces (Bos taurus)


name: C3(H2O):Factor Bb cleaves C3 to C3b and C3a (Bos taurus)


name: Factor D cleaves C3b-bound Factor B (Bos taurus)


name: Spontaneous hydrolysis of C3 thioester (Bos taurus)


name: Factor D cleaves C3(H2O)-bound Factor B (Bos taurus)


name: Factor B binds to surface-associated C3b (Bos taurus)


name: Alternative complement activation (Sus scrofa)


name: Factor B binds to surface-associated C3b (Sus scrofa)


name: C3(H2O):Factor Bb cleaves C3 to C3b and C3a (Sus scrofa)


name: Spontaneous hydrolysis of C3 thioester (Sus scrofa)


name: Factor D cleaves C3(H2O)-bound Factor B (Sus scrofa)


name: Properdin stabilizes C3b:Bb bound to cell surfaces (Sus scrofa)


name: Formation of alternative pathway C5 convertase (Sus scrofa)


name: Factor D cleaves C3b-bound Factor B (Sus scrofa)


name: Alternative complement activation (Danio rerio)


name: Spontaneous hydrolysis of C3 thioester (Danio rerio)


name: C3(H2O):Factor Bb cleaves C3 to C3b and C3a (Danio rerio)


name: Factor B binds to surface-associated C3b (Danio rerio)


name: Factor D cleaves C3b-bound Factor B (Danio rerio)


name: Factor D cleaves C3(H2O)-bound Factor B (Danio rerio)


name: Alternative complement activation (Xenopus tropicalis)


name: Factor B binds to surface-associated C3b (Xenopus tropicalis)


name: Spontaneous hydrolysis of C3 thioester (Xenopus tropicalis)


name: Formation of alternative pathway C5 convertase (Xenopus tropicalis)


name: Factor D cleaves C3b-bound Factor B (Xenopus tropicalis)


name: C3b binds to cell surface (Xenopus tropicalis)


name: Factor B binds to C3(H2O) (Xenopus tropicalis)


name: Properdin stabilizes C3b:Bb bound to cell surfaces (Xenopus tropicalis)


name: C3(H2O):Factor Bb cleaves C3 to C3b and C3a (Xenopus tropicalis)


name: Factor D cleaves C3(H2O)-bound Factor B (Xenopus tropicalis)


name: Alternative complement activation (Gallus gallus)


name: C3(H2O):Factor Bb cleaves C3 to C3b and C3a (Gallus gallus)


name: C3b binds to cell surface (Gallus gallus)


name: Spontaneous hydrolysis of C3 thioester (Gallus gallus)


name: Factor D cleaves C3b-bound Factor B (Gallus gallus)


name: Factor B binds to surface-associated C3b (Gallus gallus)


name: Factor B binds to C3(H2O) (Gallus gallus)


name: Factor D cleaves C3(H2O)-bound Factor B (Gallus gallus)


name: Initial triggering of complement (Mus musculus)


name: Conversion of C2 into C2a and C2b (Mus musculus)


name: Formation of Classical C3 convertase (C4b:C2a complex) (Mus musculus)


name: C4b binds to cell surface (Mus musculus)


name: Conversion of C4 into C4a and C4b (Mus musculus)


name: Initial triggering of complement (Rattus norvegicus)


name: Conversion of C4 into C4a and C4b (Rattus norvegicus)


name: Formation of Classical C3 convertase (C4b:C2a complex) (Rattus norvegicus)


name: C4b binds to cell surface (Rattus norvegicus)


name: Conversion of C2 into C2a and C2b (Rattus norvegicus)


name: Initial triggering of complement (Canis familiaris)


name: Conversion of C4 into C4a and C4b (Canis familiaris)


name: Conversion of C2 into C2a and C2b (Canis familiaris)


name: Formation of Classical C3 convertase (C4b:C2a complex) (Canis familiaris)


name: C4b binds to cell surface (Canis familiaris)


name: Initial triggering of complement (Bos taurus)


name: Formation of Classical C3 convertase (C4b:C2a complex) (Bos taurus)


name: Conversion of C2 into C2a and C2b (Bos taurus)


name: Conversion of C4 into C4a and C4b (Bos taurus)


name: Initial triggering of complement (Sus scrofa)


name: Conversion of C4 into C4a and C4b (Sus scrofa)


name: Conversion of C2 into C2a and C2b (Sus scrofa)


name: Formation of Classical C3 convertase (C4b:C2a complex) (Sus scrofa)


name: Initial triggering of complement (Xenopus tropicalis)


name: Formation of Classical C3 convertase (C4b:C2a complex) (Xenopus tropicalis)


name: Conversion of C2 into C2a and C2b (Xenopus tropicalis)


name: C4b binds to cell surface (Xenopus tropicalis)


name: Conversion of C4 into C4a and C4b (Xenopus tropicalis)


name: Initial triggering of complement (Gallus gallus)


name: Conversion of C4 into C4a and C4b (Gallus gallus)


name: C4b binds to cell surface (Gallus gallus)


name: Formation of Classical C3 convertase (C4b:C2a complex) (Gallus gallus)


name: Conversion of C2 into C2a and C2b (Gallus gallus)


name: Regulation of Complement cascade (Homo sapiens)


name: Complement factor I binds to membrane-associated Factor H:C3b (Homo sapiens)


name: Factor I inactivates MCP/CR1-bound C4b/C3b (Homo sapiens)


name: CR2:C3d,C3dg,iC3b binds CD19:CD81 (Homo sapiens)


name: C5AR2 binds anaphylatoxins and thier desArginated derivatives (Homo sapiens)


name: Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates (Homo sapiens)


name: Complement factor I inactivates C4BP-bound C4b (Homo sapiens)


name: Complement factor I binds to MCP, CR1:C4b, C3b (Homo sapiens)


name: CR2 binds C3d, C3dg, iC3b (Homo sapiens)


name: CPN, CPB2 cleave C3a, C5a (Homo sapiens)


name: CD55 (DAF) binds C3bBb, C4bC2a (Homo sapiens)


name: Displacement of C2a/Bb by CR1 (Homo sapiens)


name: C4b-binding protein binds C4b (Homo sapiens)


name: Complement factor I binds C4BP (Homo sapiens)


name: Factor I inactivates Factor H-boundC3b (Homo sapiens)


name: Factor H binds host cell surface markers (Homo sapiens)


name: Formation of soluble VTN:C5b-C9  (Homo sapiens)


name: CD55 (DAF) promotes C3bBb/C4bC2a dissociation (Homo sapiens)


name: C4b binding protein binds C4bC2a (Homo sapiens)


name: C3a receptor binds anaphylatoxin C3a (Homo sapiens)


name: Clusterin binds C5b-C7, C8, C9 (Homo sapiens)


name: Complement factor I binds to extracellular Factor H:C3b (Homo sapiens)


name: C5a receptor binds C5a anaphylatoxin (Homo sapiens)


name: Factor I inactivates plasma Factor H-bound C3b (Homo sapiens)


name: CD59 inhibits MAC formation (Homo sapiens)


name: Thrombin, ELANE cleave C5 (Homo sapiens)


name: Hydrolysis of internal thioester in C4b (Homo sapiens)


name: C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s (Homo sapiens)


name: Factor H binds to membrane-associated C3b (Homo sapiens)


name: Complement factor I complex formation (Homo sapiens)


name: C4b binding protein binds Protein S (Homo sapiens)


name: Vitronectin (VTN) binds to C5b:C6:C7 (Homo sapiens)


name: C1-Inh binds and inactivates C1r, C1s (Homo sapiens)


name: C3 convertases spontaneously dissociate (Homo sapiens)


name: C4b binding protein displaces C2a (Homo sapiens)


name: Regulation of Complement cascade (Mus musculus)


name: Clusterin binds C5b-C7, C8, C9 (Mus musculus)


name: C5AR2 binds anaphylatoxins and thier desArginated derivatives (Mus musculus)


name: CPN, CPB2 cleave C3a, C5a (Mus musculus)


name: Hydrolysis of internal thioester in C4b (Mus musculus)


name: Vitronectin (VTN) binds to C5b:C6:C7 (Mus musculus)


name: C1-Inh binds and inactivates C1r, C1s (Mus musculus)


name: C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s (Mus musculus)


name: CD55 (DAF) promotes C3bBb/C4bC2a dissociation (Mus musculus)


name: CD55 (DAF) binds C3bBb, C4bC2a (Mus musculus)


name: C3 convertases spontaneously dissociate (Mus musculus)


name: C5a receptor binds C5a anaphylatoxin (Mus musculus)


name: Complement factor I binds to MCP, CR1:C4b, C3b (Mus musculus)


name: CR2 binds C3d, C3dg, iC3b (Mus musculus)


name: Thrombin, ELANE cleave C5 (Mus musculus)


name: Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates (Mus musculus)


name: CD59 inhibits MAC formation (Mus musculus)


name: Factor I inactivates MCP/CR1-bound C4b/C3b (Mus musculus)


name: C3a receptor binds anaphylatoxin C3a (Mus musculus)


name: Complement factor I complex formation (Mus musculus)


name: Formation of soluble VTN:C5b-C9  (Mus musculus)


name: CR2:C3d,C3dg,iC3b binds CD19:CD81 (Mus musculus)


name: Regulation of Complement cascade (Rattus norvegicus)


name: Complement factor I binds to MCP, CR1:C4b, C3b (Rattus norvegicus)


name: CFHR dimers bind C3b (Rattus norvegicus)


name: CPN, CPB2 cleave C3a, C5a (Rattus norvegicus)


name: C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s (Rattus norvegicus)


name: Clusterin binds C5b-C7, C8, C9 (Rattus norvegicus)


name: C1-Inh binds and inactivates C1r, C1s (Rattus norvegicus)


name: Hydrolysis of internal thioester in C4b (Rattus norvegicus)


name: C5a receptor binds C5a anaphylatoxin (Rattus norvegicus)


name: Thrombin, ELANE cleave C5 (Rattus norvegicus)


name: Factor I inactivates MCP/CR1-bound C4b/C3b (Rattus norvegicus)


name: Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates (Rattus norvegicus)


name: CR1 binds C3bBb/C4bC2a (Rattus norvegicus)


name: Complement factor I complex formation (Rattus norvegicus)


name: CD55 (DAF) binds C3bBb, C4bC2a (Rattus norvegicus)


name: Factor I cleaves iC3b (Rattus norvegicus)


name: C5AR2 binds anaphylatoxins and thier desArginated derivatives (Rattus norvegicus)


name: CR2:C3d,C3dg,iC3b binds CD19:CD81 (Rattus norvegicus)


name: C3a receptor binds anaphylatoxin C3a (Rattus norvegicus)


name: CR2 binds C3d, C3dg, iC3b (Rattus norvegicus)


name: Regulation of Complement cascade (Canis familiaris)


name: CD59 inhibits MAC formation (Canis familiaris)


name: C3 convertases spontaneously dissociate (Canis familiaris)


name: Formation of soluble VTN:C5b-C9  (Canis familiaris)


name: Factor I inactivates MCP/CR1-bound C4b/C3b (Canis familiaris)


name: Complement factor I binds to extracellular Factor H:C3b (Canis familiaris)


name: CD55 (DAF) binds C3bBb, C4bC2a (Canis familiaris)


name: Factor I inactivates Factor H-boundC3b (Canis familiaris)


name: CD55 (DAF) promotes C3bBb/C4bC2a dissociation (Canis familiaris)


name: Hydrolysis of internal thioester in C4b (Canis familiaris)


name: Vitronectin (VTN) binds to C5b:C6:C7 (Canis familiaris)


name: CPN, CPB2 cleave C3a, C5a (Canis familiaris)


name: Factor I cleaves iC3b (Canis familiaris)


name: Displacement of C2a/Bb by CR1 (Canis familiaris)


name: CR1 binds C3bBb/C4bC2a (Canis familiaris)


name: Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates (Canis familiaris)


name: CR2 binds C3d, C3dg, iC3b (Canis familiaris)


name: Factor H binds to membrane-associated C3b (Canis familiaris)


name: C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s (Canis familiaris)


name: CR2:C3d,C3dg,iC3b binds CD19:CD81 (Canis familiaris)


name: C5a receptor binds C5a anaphylatoxin (Canis familiaris)


name: C1-Inh binds and inactivates C1r, C1s (Canis familiaris)


name: Factor H binds host cell surface markers (Canis familiaris)


name: Complement factor I binds to MCP, CR1:C4b, C3b (Canis familiaris)


name: Clusterin binds C5b-C7, C8, C9 (Canis familiaris)


name: C3a receptor binds anaphylatoxin C3a (Canis familiaris)


name: Complement factor I binds to membrane-associated Factor H:C3b (Canis familiaris)


name: Factor H displaces Bb (Canis familiaris)


name: Factor H binds to C3bBb (Canis familiaris)


name: Thrombin, ELANE cleave C5 (Canis familiaris)


name: C5AR2 binds anaphylatoxins and thier desArginated derivatives (Canis familiaris)


name: Factor H binds to C3b (Canis familiaris)


name: Complement factor I complex formation (Canis familiaris)


name: Factor I inactivates plasma Factor H-bound C3b (Canis familiaris)


name: Regulation of Complement cascade (Bos taurus)


name: Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates (Bos taurus)


name: C1-Inh binds and inactivates C1r, C1s (Bos taurus)


name: CR2:C3d,C3dg,iC3b binds CD19:CD81 (Bos taurus)


name: C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s (Bos taurus)


name: Complement factor I binds to membrane-associated Factor H:C3b (Bos taurus)


name: Factor I inactivates MCP/CR1-bound C4b/C3b (Bos taurus)


name: CD55 (DAF) binds C3bBb, C4bC2a (Bos taurus)


name: C3 convertases spontaneously dissociate (Bos taurus)


name: Clusterin binds C5b-C7, C8, C9 (Bos taurus)


name: CD55 (DAF) promotes C3bBb/C4bC2a dissociation (Bos taurus)


name: Formation of soluble VTN:C5b-C9  (Bos taurus)


name: CD59 inhibits MAC formation (Bos taurus)


name: Factor H binds to membrane-associated C3b (Bos taurus)


name: C3a receptor binds anaphylatoxin C3a (Bos taurus)


name: Vitronectin (VTN) binds to C5b:C6:C7 (Bos taurus)


name: Factor I inactivates Factor H-boundC3b (Bos taurus)


name: Factor H binds host cell surface markers (Bos taurus)


name: Hydrolysis of internal thioester in C4b (Bos taurus)


name: Complement factor I binds to MCP, CR1:C4b, C3b (Bos taurus)


name: C5AR2 binds anaphylatoxins and thier desArginated derivatives (Bos taurus)


name: C5a receptor binds C5a anaphylatoxin (Bos taurus)


name: Factor I inactivates plasma Factor H-bound C3b (Bos taurus)


name: Complement factor I binds to extracellular Factor H:C3b (Bos taurus)


name: Complement factor I complex formation (Bos taurus)


name: Regulation of Complement cascade (Sus scrofa)


name: CD59 inhibits MAC formation (Sus scrofa)


name: Complement factor I complex formation (Sus scrofa)


name: Vitronectin (VTN) binds to C5b:C6:C7 (Sus scrofa)


name: Factor I inactivates MCP/CR1-bound C4b/C3b (Sus scrofa)


name: Complement factor I binds to extracellular Factor H:C3b (Sus scrofa)


name: CR2:C3d,C3dg,iC3b binds CD19:CD81 (Sus scrofa)


name: C1-Inh binds and inactivates C1r, C1s (Sus scrofa)


name: CD55 (DAF) binds C3bBb, C4bC2a (Sus scrofa)


name: C3 convertases spontaneously dissociate (Sus scrofa)


name: CD55 (DAF) promotes C3bBb/C4bC2a dissociation (Sus scrofa)


name: Clusterin binds C5b-C7, C8, C9 (Sus scrofa)


name: Factor I inactivates Factor H-boundC3b (Sus scrofa)


name: Displacement of C2a/Bb by CR1 (Sus scrofa)


name: C5a receptor binds C5a anaphylatoxin (Sus scrofa)


name: Hydrolysis of internal thioester in C4b (Sus scrofa)


name: Factor H binds host cell surface markers (Sus scrofa)


name: C5AR2 binds anaphylatoxins and thier desArginated derivatives (Sus scrofa)


name: Factor H binds to membrane-associated C3b (Sus scrofa)


name: Complement factor I binds to MCP, CR1:C4b, C3b (Sus scrofa)


name: C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s (Sus scrofa)


name: Complement factor I binds to membrane-associated Factor H:C3b (Sus scrofa)


name: Formation of soluble VTN:C5b-C9  (Sus scrofa)


name: Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates (Sus scrofa)


name: Factor I inactivates plasma Factor H-bound C3b (Sus scrofa)


name: Regulation of Complement cascade (Danio rerio)


name: Factor H binds host cell surface markers (Danio rerio)


name: Factor H binds to membrane-associated C3b (Danio rerio)


name: Regulation of Complement cascade (Xenopus tropicalis)


name: Factor I inactivates Factor H-boundC3b (Xenopus tropicalis)


name: Complement factor I complex formation (Xenopus tropicalis)


name: CFHR dimers bind C3b (Xenopus tropicalis)


name: Factor H binds to C3b (Xenopus tropicalis)


name: Complement factor I binds to membrane-associated Factor H:C3b (Xenopus tropicalis)


name: Factor I inactivates plasma Factor H-bound C3b (Xenopus tropicalis)


name: CPN, CPB2 cleave C3a, C5a (Xenopus tropicalis)


name: C3 convertases spontaneously dissociate (Xenopus tropicalis)


name: C3a receptor binds anaphylatoxin C3a (Xenopus tropicalis)


name: CD55 (DAF) promotes C3bBb/C4bC2a dissociation (Xenopus tropicalis)


name: CD55 (DAF) binds C3bBb, C4bC2a (Xenopus tropicalis)


name: Hydrolysis of internal thioester in C4b (Xenopus tropicalis)


name: Factor H binds to membrane-associated C3b (Xenopus tropicalis)


name: Factor H displaces Bb (Xenopus tropicalis)


name: Factor H binds to C3bBb (Xenopus tropicalis)


name: Factor H binds host cell surface markers (Xenopus tropicalis)


name: Complement factor I binds to extracellular Factor H:C3b (Xenopus tropicalis)


name: Regulation of Complement cascade (Gallus gallus)


name: C5AR2 binds anaphylatoxins and thier desArginated derivatives (Gallus gallus)


name: C3a receptor binds anaphylatoxin C3a (Gallus gallus)


name: C1-Inh binds and inactivates C1r, C1s (Gallus gallus)


name: CD55 (DAF) promotes C3bBb/C4bC2a dissociation (Gallus gallus)


name: Factor H binds to membrane-associated C3b (Gallus gallus)


name: Thrombin, ELANE cleave C5 (Gallus gallus)


name: Displacement of C2a/Bb by CR1 (Gallus gallus)


name: C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s (Gallus gallus)


name: Complement factor I complex formation (Gallus gallus)


name: Complement factor I binds to extracellular Factor H:C3b (Gallus gallus)


name: Factor I inactivates plasma Factor H-bound C3b (Gallus gallus)


name: Factor I inactivates MCP/CR1-bound C4b/C3b (Gallus gallus)


name: Factor I inactivates Factor H-boundC3b (Gallus gallus)


name: CD55 (DAF) binds C3bBb, C4bC2a (Gallus gallus)


name: C5a receptor binds C5a anaphylatoxin (Gallus gallus)


name: CR2 binds C3d, C3dg, iC3b (Gallus gallus)


name: Factor H binds host cell surface markers (Gallus gallus)


name: Vitronectin (VTN) binds to C5b:C6:C7 (Gallus gallus)


name: Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates (Gallus gallus)


name: Hydrolysis of internal thioester in C4b (Gallus gallus)


name: Complement factor I binds to MCP, CR1:C4b, C3b (Gallus gallus)


name: CPN, CPB2 cleave C3a, C5a (Gallus gallus)


name: Complement factor I binds to membrane-associated Factor H:C3b (Gallus gallus)


name: Regulation of Complement cascade (Drosophila melanogaster)


name: Complement factor I complex formation (Drosophila melanogaster)


name: Terminal pathway of complement (Homo sapiens)


name: C5b:C6:C7 translocates to the plasma membrane (Homo sapiens)


name: Terminal pathway of complement (Mus musculus)


name: C5b:C6:C7 translocates to the plasma membrane (Mus musculus)


name: Terminal pathway of complement (Rattus norvegicus)


name: Terminal pathway of complement (Canis familiaris)


name: C9 binds C5b:C6:C7:C8 (Canis familiaris)


name: C5b:C6:C7 translocates to the plasma membrane (Canis familiaris)


name: Terminal pathway of complement (Bos taurus)


name: C5b:C6:C7 translocates to the plasma membrane (Bos taurus)


name: Terminal pathway of complement (Sus scrofa)


name: C5b:C6:C7 translocates to the plasma membrane (Sus scrofa)


name: Terminal pathway of complement (Gallus gallus)


name: C5b:C6:C7 translocates to the plasma membrane (Gallus gallus)


name: TXNIP is released from oxidized thioredoxin (Homo sapiens)


name: NLRP3 oligomerizes via NACHT domains (Homo sapiens)


name: NLRP3 activation by elicitor proteins (Homo sapiens)


name: SGT1:HSP90 binds inactive NLRP3 (Homo sapiens)


name: NLRP3 activation by small molecules (Homo sapiens)


name: NLRP3 recruits PYCARD (ASC) via a PYD-PYD interaction (Homo sapiens)


name: extracellularly ATP-gated monoatomic cation channel activity

description: Enables the transmembrane transfer of a monoatomic cation by a channel that opens when ATP is bound by the channel complex or one of its constituent parts on the extracellular side of the plasma membrane.


name: TXNIP binds reduced thioredoxin (Homo sapiens)


name: P2X7 forms oligomeric non-selective cation channels (Homo sapiens)


name: PYCARD recruits procaspase-1 via CARD (Homo sapiens)


name: P2X7 mediates membrane pores that include pannexin-1 (Homo sapiens)


name: NLRP3 activation by small molecules (Mus musculus)


name: P2X7 mediates loss of intracellular K+ (Mus musculus)


name: TXNIP binds reduced thioredoxin (Mus musculus)


name: P2X7 mediates membrane pores that include pannexin-1 (Mus musculus)


name: SGT1:HSP90 binds inactive NLRP3 (Mus musculus)


name: The NLRP3 inflammasome (Rattus norvegicus)


name: NLRP3 activation by small molecules (Rattus norvegicus)


name: P2X7 mediates loss of intracellular K+ (Rattus norvegicus)


name: SGT1:HSP90 binds inactive NLRP3 (Rattus norvegicus)


name: ROS oxidize thioredoxin (Rattus norvegicus)


name: TXNIP binds reduced thioredoxin (Rattus norvegicus)


name: P2X7 mediates membrane pores that include pannexin-1 (Rattus norvegicus)


name: The NLRP3 inflammasome (Canis familiaris)


name: SGT1:HSP90 binds inactive NLRP3 (Canis familiaris)


name: NLRP3 activation by small molecules (Canis familiaris)


name: P2X7 mediates membrane pores that include pannexin-1 (Canis familiaris)


name: TXNIP binds reduced thioredoxin (Canis familiaris)


name: P2X7 mediates loss of intracellular K+ (Canis familiaris)


name: ROS oxidize thioredoxin (Canis familiaris)


name: TXNIP binds reduced thioredoxin (Bos taurus)


name: NLRP3 activation by small molecules (Bos taurus)


name: P2X7 mediates membrane pores that include pannexin-1 (Bos taurus)


name: SGT1:HSP90 binds inactive NLRP3 (Bos taurus)


name: P2X7 mediates loss of intracellular K+ (Bos taurus)


name: TXNIP binds reduced thioredoxin (Sus scrofa)


name: P2X7 mediates loss of intracellular K+ (Sus scrofa)


name: NLRP3 activation by small molecules (Sus scrofa)


name: SGT1:HSP90 binds inactive NLRP3 (Sus scrofa)


name: P2X7 mediates membrane pores that include pannexin-1 (Sus scrofa)


name: NLRP3 activation by small molecules (Danio rerio)


name: SGT1:HSP90 binds inactive NLRP3 (Danio rerio)


name: P2X7 mediates membrane pores that include pannexin-1 (Danio rerio)


name: P2X7 mediates loss of intracellular K+ (Danio rerio)


name: TXNIP binds reduced thioredoxin (Danio rerio)


name: The NLRP3 inflammasome (Xenopus tropicalis)


name: NLRP3 activation by small molecules (Xenopus tropicalis)


name: SGT1:HSP90 binds inactive NLRP3 (Xenopus tropicalis)


name: TXNIP binds reduced thioredoxin (Gallus gallus)


name: SGT1:HSP90 binds inactive NLRP3 (Gallus gallus)


name: P2X7 mediates membrane pores that include pannexin-1 (Gallus gallus)


name: P2X7 mediates loss of intracellular K+ (Gallus gallus)


name: NLRP3 activation by small molecules (Gallus gallus)


name: The NLRP3 inflammasome (Drosophila melanogaster)


name: ROS oxidize thioredoxin (Drosophila melanogaster)


name: TXNIP binds reduced thioredoxin (Drosophila melanogaster)


name: SGT1 binds HSP90 (Drosophila melanogaster)


name: The NLRP3 inflammasome (Caenorhabditis elegans)


name: ROS oxidize thioredoxin (Caenorhabditis elegans)


name: TXNIP binds reduced thioredoxin (Caenorhabditis elegans)


name: The NLRP3 inflammasome (Dictyostelium discoideum)


name: ROS oxidize thioredoxin (Dictyostelium discoideum)


name: SGT1 binds HSP90 (Dictyostelium discoideum)


name: P2X7 mediates loss of intracellular K+ (Dictyostelium discoideum)


name: The NLRP3 inflammasome (Schizosaccharomyces pombe)


name: SGT1 binds HSP90 (Schizosaccharomyces pombe)


name: TXNIP binds reduced thioredoxin (Schizosaccharomyces pombe)


name: ROS oxidize thioredoxin (Schizosaccharomyces pombe)


name: The NLRP3 inflammasome (Saccharomyces cerevisiae)


name: TXNIP binds reduced thioredoxin (Saccharomyces cerevisiae)


name: ROS oxidize thioredoxin (Saccharomyces cerevisiae)


name: SGT1 binds HSP90 (Saccharomyces cerevisiae)


name: The NLRP3 inflammasome (Plasmodium falciparum)


name: ROS oxidize thioredoxin (Plasmodium falciparum)


name: Bcl-2 and Bcl-XL bind NLRP1 (Homo sapiens)


name: MDP:NLRP1 binds ATP (Homo sapiens)


name: MDP:NLRP1 binds ATP (Mus musculus)


name: Bcl-2 and Bcl-XL bind NLRP1 (Mus musculus)


name: The NLRP1 inflammasome (Rattus norvegicus)


name: Bcl-2 and Bcl-XL bind NLRP1 (Rattus norvegicus)


name: MDP:NLRP1 binds ATP (Rattus norvegicus)


name: The NLRP1 inflammasome (Canis familiaris)


name: Bcl-2 and Bcl-XL bind NLRP1 (Canis familiaris)


name: MDP:NLRP1 binds ATP (Canis familiaris)


name: MDP:NLRP1 binds ATP (Bos taurus)


name: Bcl-2 and Bcl-XL bind NLRP1 (Bos taurus)


name: MDP:NLRP1 binds ATP (Danio rerio)


name: Bcl-2 and Bcl-XL bind NLRP1 (Danio rerio)


name: Bcl-2 and Bcl-XL bind NLRP1 (Gallus gallus)


name: MDP:NLRP1 binds ATP (Gallus gallus)


name: dsDNA:AIM2:ASC cluster binds procaspase-1 (Homo sapiens)


name: dsDNA:AIM2 clusters bind ASC (Homo sapiens)


name: The AIM2 inflammasome (Rattus norvegicus)


name: MDP elicits a NOD2 response (Homo sapiens)


name: NOD1 induced apoptosis is mediated by RIP2 and CARD8 (Homo sapiens)


name: CARD9 binds RIP2 (and NOD2) (Homo sapiens)


name: Activated NOD oligomer recruites RIP2 (RICK) (Homo sapiens)


name: Activated NOD2 oligomerizes (Homo sapiens)


name: K63 polyubiquitinated RIP2 associates with the TAK1 complex (Homo sapiens)


name: iE-DAP elicits a NOD1 response (Homo sapiens)


name: Activated NOD1 oligomerizes (Homo sapiens)


name: CYLD deubiquitinates NEMO (Homo sapiens)


name: RIP2 is K63 polyubiquitinated (Homo sapiens)


name: TNFAIP3 (A20) deubiquitinates RIP2 (Homo sapiens)


name: RIP2 induces K63-linked ubiquitination of NEMO (Homo sapiens)


name: RIP2 is K63 polyubiquitinated (Mus musculus)


name: RIP2 induces K63-linked ubiquitination of NEMO (Mus musculus)


name: CYLD deubiquitinates NEMO (Mus musculus)


name: TNFAIP3 (A20) deubiquitinates RIP2 (Mus musculus)


name: Activated NOD1 oligomerizes (Mus musculus)


name: NOD1 induced apoptosis is mediated by RIP2 and CARD8 (Mus musculus)


name: iE-DAP elicits a NOD1 response (Mus musculus)


name: Activated NOD oligomer recruites RIP2 (RICK) (Mus musculus)


name: MDP elicits a NOD2 response (Mus musculus)


name: K63 polyubiquitinated RIP2 associates with the TAK1 complex (Mus musculus)


name: Activated NOD2 oligomerizes (Mus musculus)


name: NOD1/2 Signaling Pathway (Rattus norvegicus)


name: RIP2 is K63 polyubiquitinated (Rattus norvegicus)


name: Activation of p38 MAPK (Rattus norvegicus)


name: NOD1 induced apoptosis is mediated by RIP2 and CARD8 (Rattus norvegicus)


name: Activated NOD1 oligomerizes (Rattus norvegicus)


name: MDP elicits a NOD2 response (Rattus norvegicus)


name: Activated NOD oligomer recruites RIP2 (RICK) (Rattus norvegicus)


name: Activated NOD2 oligomerizes (Rattus norvegicus)


name: CYLD deubiquitinates NEMO (Rattus norvegicus)


name: K63 polyubiquitinated RIP2 associates with the TAK1 complex (Rattus norvegicus)


name: TAK1 phosphorylates MKK6 (Rattus norvegicus)


name: TNFAIP3 (A20) deubiquitinates RIP2 (Rattus norvegicus)


name: iE-DAP elicits a NOD1 response (Rattus norvegicus)


name: NOD1/2 Signaling Pathway (Canis familiaris)


name: Activated NOD oligomer recruites RIP2 (RICK) (Canis familiaris)


name: MDP elicits a NOD2 response (Canis familiaris)


name: Activated NOD1 oligomerizes (Canis familiaris)


name: RIP2 is K63 polyubiquitinated (Canis familiaris)


name: RIP2 induces K63-linked ubiquitination of NEMO (Canis familiaris)


name: CYLD deubiquitinates NEMO (Canis familiaris)


name: Activated NOD2 oligomerizes (Canis familiaris)


name: Activation of p38 MAPK (Canis familiaris)


name: iE-DAP elicits a NOD1 response (Canis familiaris)


name: K63 polyubiquitinated RIP2 associates with the TAK1 complex (Canis familiaris)


name: NOD1 induced apoptosis is mediated by RIP2 and CARD8 (Canis familiaris)


name: TNFAIP3 (A20) deubiquitinates RIP2 (Canis familiaris)


name: TAK1 phosphorylates MKK6 (Canis familiaris)


name: Activated NOD2 oligomerizes (Bos taurus)


name: RIP2 is K63 polyubiquitinated (Bos taurus)


name: K63 polyubiquitinated RIP2 associates with the TAK1 complex (Bos taurus)


name: MDP elicits a NOD2 response (Bos taurus)


name: TNFAIP3 (A20) deubiquitinates RIP2 (Bos taurus)


name: Activated NOD oligomer recruites RIP2 (RICK) (Bos taurus)


name: Activated NOD2 oligomerizes (Danio rerio)


name: RIP2 induces K63-linked ubiquitination of NEMO (Danio rerio)


name: RIP2 is K63 polyubiquitinated (Danio rerio)


name: Activated NOD oligomer recruites RIP2 (RICK) (Danio rerio)


name: MDP elicits a NOD2 response (Danio rerio)


name: NOD1/2 Signaling Pathway (Xenopus tropicalis)


name: RIP2 is K63 polyubiquitinated (Xenopus tropicalis)


name: TAK1 phosphorylates MKK6 (Xenopus tropicalis)


name: K63 polyubiquitinated RIP2 associates with the TAK1 complex (Xenopus tropicalis)


name: iE-DAP elicits a NOD1 response (Xenopus tropicalis)


name: Activation of p38 MAPK (Xenopus tropicalis)


name: Activated NOD oligomer recruites RIP2 (RICK) (Xenopus tropicalis)


name: Activated NOD1 oligomerizes (Xenopus tropicalis)


name: NOD1/2 Signaling Pathway (Gallus gallus)


name: TAK1 phosphorylates MKK6 (Gallus gallus)


name: NOD1/2 Signaling Pathway (Drosophila melanogaster)


name: Activation of p38 MAPK (Drosophila melanogaster)


name: NOD1/2 Signaling Pathway (Caenorhabditis elegans)


name: Activation of p38 MAPK (Caenorhabditis elegans)


name: NOD1/2 Signaling Pathway (Dictyostelium discoideum)


name: MDP elicits a NOD2 response (Dictyostelium discoideum)


name: iE-DAP elicits a NOD1 response (Dictyostelium discoideum)


name: Activation of p38 MAPK (Dictyostelium discoideum)


name: AAMP binds NOD2 (Dictyostelium discoideum)


name: Activated NOD1 oligomerizes (Dictyostelium discoideum)


name: Activated NOD2 oligomerizes (Dictyostelium discoideum)


name: DDX58/IFIH1-mediated induction of interferon-alpha/beta (Homo sapiens)


name: viral dsRNA binds IFIH1:TKFC (Homo sapiens)


name: HSP90 binds TBK1 and IRF3 (Homo sapiens)


name: viral dsRNA:IFIH1, viral dsRNA:K63polyUb-DDX58 bind MAVS (Homo sapiens)


name: Negative regulators of DDX58/IFIH1 signaling (Homo sapiens)


name: NLRX1 inhibits MAVS-DDX58 interaction. (Homo sapiens)


name: TAX1BP1:A20 inhibit TBK1/IKKi K63-polyubiquitination (Homo sapiens)


name: Negative regulation of DDX58/IFIH1 signaling by RNF216 (Homo sapiens)


name: Inhibition of DDX58/IFIH1 signaling by ATG5:ATG12:MAVS (Homo sapiens)


name: OTUD5 deubiquitinates TRAF3 (Homo sapiens)


name: Interaction of PIN1 with p-IRF3 (Homo sapiens)


name: RNF125 mediated ubiquitination of DDX58, IFIH1 and MAVS (Homo sapiens)


name: Recruitment of ITCH and K48 ubiquitination of MAVS (Homo sapiens)


name: NLRC5 interacts with DDX58/IFIH1 (Homo sapiens)


name: Interaction of PCBP2 with MAVS (Homo sapiens)


name: CYLD mediated deubiquitination of DDX58 (RIG-I) (Homo sapiens)


name: PIN1 mediated IRF3 degradation (Homo sapiens)


name: Negative regulators of DDX58/IFIH1 signaling (Mus musculus)


name: NLRX1 inhibits MAVS-DDX58 interaction. (Mus musculus)


name: CYLD mediated deubiquitination of DDX58 (RIG-I) (Mus musculus)


name: TAX1BP1:A20 inhibit TBK1/IKKi K63-polyubiquitination (Mus musculus)


name: Interaction of PIN1 with p-IRF3 (Mus musculus)


name: Negative regulators of DDX58/IFIH1 signaling (Rattus norvegicus)


name: NLRX1 inhibits MAVS-DDX58 interaction. (Rattus norvegicus)


name: CYLD mediated deubiquitination of DDX58 (RIG-I) (Rattus norvegicus)


name: TAX1BP1:A20 inhibit TBK1/IKKi K63-polyubiquitination (Rattus norvegicus)


name: Interaction of PIN1 with p-IRF3 (Rattus norvegicus)


name: Negative regulators of DDX58/IFIH1 signaling (Canis familiaris)


name: TAX1BP1:A20 inhibit TBK1/IKKi K63-polyubiquitination (Canis familiaris)


name: Interaction of PIN1 with p-IRF3 (Canis familiaris)


name: NLRX1 inhibits MAVS-DDX58 interaction. (Canis familiaris)


name: Negative regulators of DDX58/IFIH1 signaling (Bos taurus)


name: CYLD mediated deubiquitination of DDX58 (RIG-I) (Bos taurus)


name: NLRX1 inhibits MAVS-DDX58 interaction. (Bos taurus)


name: Interaction of PIN1 with p-IRF3 (Bos taurus)


name: TAX1BP1:A20 inhibit TBK1/IKKi K63-polyubiquitination (Bos taurus)


name: Negative regulators of DDX58/IFIH1 signaling (Sus scrofa)


name: Interaction of PIN1 with p-IRF3 (Sus scrofa)


name: TAX1BP1:A20 inhibit TBK1/IKKi K63-polyubiquitination (Sus scrofa)


name: CYLD mediated deubiquitination of DDX58 (RIG-I) (Sus scrofa)


name: Negative regulators of DDX58/IFIH1 signaling (Danio rerio)


name: NLRX1 inhibits MAVS-DDX58 interaction. (Danio rerio)


name: Negative regulators of DDX58/IFIH1 signaling (Gallus gallus)


name: TAX1BP1:A20 inhibit TBK1/IKKi K63-polyubiquitination (Gallus gallus)


name: NLRX1 inhibits MAVS-DDX58 interaction. (Gallus gallus)


name: Negative regulators of DDX58/IFIH1 signaling (Caenorhabditis elegans)


name: CYLD mediated deubiquitination of DDX58 (RIG-I) (Caenorhabditis elegans)


name: ISGylation of DDX58 (Caenorhabditis elegans)


name: Negative regulators of DDX58/IFIH1 signaling (Dictyostelium discoideum)


name: CYLD mediated deubiquitination of DDX58 (RIG-I) (Dictyostelium discoideum)


name: ISGylation of DDX58 (Dictyostelium discoideum)


name: Negative regulators of DDX58/IFIH1 signaling (Saccharomyces cerevisiae)


name: CYLD mediated deubiquitination of DDX58 (RIG-I) (Saccharomyces cerevisiae)


name: Negative regulators of DDX58/IFIH1 signaling (Plasmodium falciparum)


name: CYLD mediated deubiquitination of DDX58 (RIG-I) (Plasmodium falciparum)


name: ISGylation of DDX58 (Plasmodium falciparum)


name: TRAF3-dependent IRF activation pathway (Homo sapiens)


name: Translocation of phosphorylated IRF3,IRF7 dimers into nucleus (Homo sapiens)


name: CREBBP, EP300 binds p-T,4S-IRF3:p-T,4S-IRF3 (Homo sapiens)


name: Recruitment of TRAF3 to MAVS (Homo sapiens)


name: Phosphorylation and release of IRF3/IRF7 (Homo sapiens)


name: Dimerization of Phospho IRF3 or phospho IRF7 (Homo sapiens)


name: TBK1 or IKBKE forms homodimers (Homo sapiens)


name: Expression of interferon-beta (Homo sapiens)


name: p-T,4S-IRF3:p-T,4S-IRF3:CREBBP, EP300 binds promoters of Interferon-beta (Homo sapiens)


name: TRAF3-dependent IRF activation pathway (Mus musculus)


name: Translocation of phosphorylated IRF3,IRF7 dimers into nucleus (Mus musculus)


name: Dimerization of Phospho IRF3 or phospho IRF7 (Mus musculus)


name: TRAF3-dependent IRF activation pathway (Rattus norvegicus)


name: Dimerization of Phospho IRF3 or phospho IRF7 (Rattus norvegicus)


name: Translocation of phosphorylated IRF3,IRF7 dimers into nucleus (Rattus norvegicus)


name: TRAF3-dependent IRF activation pathway (Bos taurus)


name: Translocation of phosphorylated IRF3,IRF7 dimers into nucleus (Bos taurus)


name: Dimerization of Phospho IRF3 or phospho IRF7 (Bos taurus)


name: TRAF3-dependent IRF activation pathway (Sus scrofa)


name: Dimerization of Phospho IRF3 or phospho IRF7 (Sus scrofa)


name: Translocation of phosphorylated IRF3,IRF7 dimers into nucleus (Sus scrofa)


name: TRAF6 mediated NF-kB activation (Homo sapiens)


name: Active IKK Complex phosphorylates NF-kappa-B inhibitor  (Homo sapiens)


name: Interaction of MEKK1 with TRAF6 (Homo sapiens)


name: NF-kappa-B complex is transported from cytosol to nucleus (Homo sapiens)


name: Activation of IKK by MEKK1 (Homo sapiens)


name: TRAF6 mediated NF-kB activation (Mus musculus)


name: Active IKK Complex phosphorylates NF-kappa-B inhibitor  (Mus musculus)


name: NF-kappa-B complex is transported from cytosol to nucleus (Mus musculus)


name: TRAF6 mediated NF-kB activation (Rattus norvegicus)


name: Active IKK Complex phosphorylates NF-kappa-B inhibitor  (Rattus norvegicus)


name: NF-kappa-B complex is transported from cytosol to nucleus (Rattus norvegicus)


name: TRAF6 mediated NF-kB activation (Canis familiaris)


name: Active IKK Complex phosphorylates NF-kappa-B inhibitor  (Canis familiaris)


name: NF-kappa-B complex is transported from cytosol to nucleus (Canis familiaris)


name: TRAF6 mediated NF-kB activation (Bos taurus)


name: NF-kappa-B complex is transported from cytosol to nucleus (Bos taurus)


name: Active IKK Complex phosphorylates NF-kappa-B inhibitor  (Bos taurus)


name: TRAF6 mediated NF-kB activation (Sus scrofa)


name: Active IKK Complex phosphorylates NF-kappa-B inhibitor  (Sus scrofa)


name: NF-kappa-B complex is transported from cytosol to nucleus (Sus scrofa)


name: TRAF6 mediated NF-kB activation (Danio rerio)


name: NF-kappa-B complex is transported from cytosol to nucleus (Danio rerio)


name: TRAF6 mediated NF-kB activation (Gallus gallus)


name: NF-kappa-B complex is transported from cytosol to nucleus (Gallus gallus)


name: TRAF6 mediated NF-kB activation (Drosophila melanogaster)


name: NF-kappa-B complex is transported from cytosol to nucleus (Drosophila melanogaster)


name: Active IKK Complex phosphorylates NF-kappa-B inhibitor  (Drosophila melanogaster)


name: NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 (Homo sapiens)


name: Recruitment of IKK complex (Homo sapiens)


name: Dimerzation of procaspase-8, procaspase-10 (Homo sapiens)


name: Recruitment of caspase-8 and -10 to FADD complex (Homo sapiens)


name: MAVS interacts with RIPK1 and FADD (Homo sapiens)


name: TRAF6 mediated IRF7 activation (Homo sapiens)


name: Phosphorylation of TBK1/IKBKE (Homo sapiens)


name: VAF/pIRF7:CBP/p300 binds the promoters of type-I IFN genes (Homo sapiens)


name: Formation of VAF (virus-activated factor) complex (Homo sapiens)


name: Phosphorylation and release of IRF7 (Homo sapiens)


name: Recruitment of TBK1/IKK epsilon complex to TANK:TRAF6 (Homo sapiens)


name: Recruitment of TRAF6/TRAF2 to IPS-1 (Homo sapiens)


name: Translocation of p-IRF7:p-IRF7 to nucleus (Homo sapiens)


name: Recruitment of TANK to TRAF6 (Homo sapiens)


name: p-IRF7 dimer interacts with coactivator CBP/p300 (Homo sapiens)


name: TBK1, IKBKE form homodimers (Homo sapiens)


name: Recruitment of IRF7 to TRAF6 (Homo sapiens)


name: Expression of Interferon-alpha and beta mediated by VAF/pIRF7:CBP/p300 (Homo sapiens)


name: TRAF6 mediated IRF7 activation (Mus musculus)


name: p-IRF7 dimer interacts with coactivator CBP/p300 (Mus musculus)


name: Translocation of p-IRF7:p-IRF7 to nucleus (Mus musculus)


name: Formation of VAF (virus-activated factor) complex (Mus musculus)


name: TRAF6 mediated IRF7 activation (Rattus norvegicus)


name: Formation of VAF (virus-activated factor) complex (Rattus norvegicus)


name: Dimerization of p-IRF7 (Rattus norvegicus)


name: Translocation of p-IRF7:p-IRF7 to nucleus (Rattus norvegicus)


name: p-IRF7 dimer interacts with coactivator CBP/p300 (Rattus norvegicus)


name: TRAF6 mediated IRF7 activation (Bos taurus)


name: Formation of VAF (virus-activated factor) complex (Bos taurus)


name: p-IRF7 dimer interacts with coactivator CBP/p300 (Bos taurus)


name: Translocation of p-IRF7:p-IRF7 to nucleus (Bos taurus)


name: TRAF6 mediated IRF7 activation (Sus scrofa)


name: Formation of VAF (virus-activated factor) complex (Sus scrofa)


name: p-IRF7 dimer interacts with coactivator CBP/p300 (Sus scrofa)


name: Translocation of p-IRF7:p-IRF7 to nucleus (Sus scrofa)


name: TRAF6 mediated IRF7 activation (Xenopus tropicalis)


name: p-IRF7 dimer interacts with coactivator CBP/p300 (Xenopus tropicalis)


name: Dimerization of p-IRF7 (Xenopus tropicalis)


name: Translocation of p-IRF7:p-IRF7 to nucleus (Xenopus tropicalis)


name: TRAF6 mediated IRF7 activation (Gallus gallus)


name: Translocation of p-IRF7:p-IRF7 to nucleus (Gallus gallus)


name: p-IRF7 dimer interacts with coactivator CBP/p300 (Gallus gallus)


name: G protein binds CX3CR1 on host cell surface (Homo sapiens)


name: NS1 (1C) binds to Mediator complex (Homo sapiens)


name: RSV ssRNA binds C-ter TLR7 dimer (Homo sapiens)


name: RSV F binds TLR4:LY96:CD14 (Homo sapiens)


name: SH pentamer transports K+ (Homo sapiens)


name: Evasion by RSV of host interferon responses (Homo sapiens)


name: Recruitment of STAT2 to p-IFNAR1 (Homo sapiens)


name: Association of NS1 (1C) with Cul5 and SCF (Homo sapiens)


name: RSV NS1 (1C) binds TRIM25 (Homo sapiens)


name: Trafficking and processing of endosomal TLR (Homo sapiens)


name: Endosomal TLRs pass through the Golgi (Homo sapiens)


name: TLR9 processing at neutral pH (Homo sapiens)


name: Folded full-length TLR7/8/9 dissociates from the GP96:CNPY3 complex  (Homo sapiens)


name: UNC93B1 delivers endosomal full-length TLRs to endolysosome (Homo sapiens)


name: TLR folding by chaperones GP96 and CNPY3 (Homo sapiens)


name: Full-length TLR3/7/8/9 binds to UNC93B1 (Homo sapiens)


name: Trafficking and processing of endosomal TLR (Mus musculus)


name: Folded full-length TLR7/8/9 dissociates from the GP96:CNPY3 complex  (Mus musculus)


name: Endosomal TLRs pass through the Golgi (Mus musculus)


name: Full-length TLR3/7/8/9 binds to UNC93B1 (Mus musculus)


name: TLR folding by chaperones GP96 and CNPY3 (Mus musculus)


name: TLR9 processing at neutral pH (Mus musculus)


name: Trafficking and processing of endosomal TLR (Rattus norvegicus)


name: TLR processing at low pH (Rattus norvegicus)


name: Folded full-length TLR7/8/9 dissociates from the GP96:CNPY3 complex  (Rattus norvegicus)


name: Endosomal TLRs pass through the Golgi (Rattus norvegicus)


name: TLR9 processing at neutral pH (Rattus norvegicus)


name: Full-length TLR3/7/8/9 binds to UNC93B1 (Rattus norvegicus)


name: TLR folding by chaperones GP96 and CNPY3 (Rattus norvegicus)


name: Trafficking and processing of endosomal TLR (Canis familiaris)


name: TLR9 processing at neutral pH (Canis familiaris)


name: Folded full-length TLR7/8/9 dissociates from the GP96:CNPY3 complex  (Canis familiaris)


name: Endosomal TLRs pass through the Golgi (Canis familiaris)


name: TLR processing at low pH (Canis familiaris)


name: UNC93B1 delivers endosomal full-length TLRs to endolysosome (Canis familiaris)


name: Full-length TLR3/7/8/9 binds to UNC93B1 (Canis familiaris)


name: TLR folding by chaperones GP96 and CNPY3 (Canis familiaris)


name: Trafficking and processing of endosomal TLR (Bos taurus)


name: TLR9 processing at neutral pH (Bos taurus)


name: Full-length TLR3/7/8/9 binds to UNC93B1 (Bos taurus)


name: TLR folding by chaperones GP96 and CNPY3 (Bos taurus)


name: Folded full-length TLR7/8/9 dissociates from the GP96:CNPY3 complex  (Bos taurus)


name: Endosomal TLRs pass through the Golgi (Bos taurus)


name: Trafficking and processing of endosomal TLR (Sus scrofa)


name: Endosomal TLRs pass through the Golgi (Sus scrofa)


name: Folded full-length TLR7/8/9 dissociates from the GP96:CNPY3 complex  (Sus scrofa)


name: Full-length TLR3/7/8/9 binds to UNC93B1 (Sus scrofa)


name: TLR folding by chaperones GP96 and CNPY3 (Sus scrofa)


name: TLR9 processing at neutral pH (Sus scrofa)


name: Trafficking and processing of endosomal TLR (Danio rerio)


name: Full-length TLR3/7/8/9 binds to UNC93B1 (Danio rerio)


name: Endosomal TLRs pass through the Golgi (Danio rerio)


name: Trafficking and processing of endosomal TLR (Xenopus tropicalis)


name: Endosomal TLRs pass through the Golgi (Xenopus tropicalis)


name: Full-length TLR3/7/8/9 binds to UNC93B1 (Xenopus tropicalis)


name: Trafficking and processing of endosomal TLR (Gallus gallus)


name: Endosomal TLRs pass through the Golgi (Gallus gallus)


name: Folded full-length TLR7/8/9 dissociates from the GP96:CNPY3 complex  (Gallus gallus)


name: TLR folding by chaperones GP96 and CNPY3 (Gallus gallus)


name: Full-length TLR3/7/8/9 binds to UNC93B1 (Gallus gallus)


name: Toll Like Receptor 5 (TLR5) Cascade (Homo sapiens)


name: MyD88 cascade initiated on plasma membrane (Homo sapiens)


name: TRAF6 binds to hp- IRAK1 or p-IRAK2 (Homo sapiens)


name: Phosphorylation of IRAK2 bound to the activated IRAK4:MyD88 oligomerl:activated TLR5 or 10 complex (Homo sapiens)


name: IRAK4 autophosphorylation within the complex activated TLR:MyD88 (Homo sapiens)


name: MyD88 forms a complex with the activated TLR receptor (Homo sapiens)


name: IRAK4 binds to MyD88 bound to the activated TLR5 or 10 receptor (Homo sapiens)


name: Second phosphorylation of IRAK1 by IRAK4 bound to MyD88:activated TLR complex (Homo sapiens)


name: Dissociation of hp-IRAK1:TRAF6 or IRAK2:TRAF6-oligomer from the activated TLR5 or 10:oligo-Myd88:p-IRAK4 complex (Homo sapiens)


name: First phosphorylation of IRAK1 by IRAK4 bound to MyD88:activated TLR (Homo sapiens)


name: MyD88 oligomerization within the complex of activated TLR:MyD88 (Homo sapiens)


name: Multiple IRAK1 autophosphorylation within the complex p-IRAK4:oligo MyD88:activated TLR (Homo sapiens)


name: IRAK1/or IRAK2 binds to the activated IRAK4 :oligo MyD88:activated TLR5 or 10 complex (Homo sapiens)


name: IRAK1 recruits IKK complex (Homo sapiens)


name: Pellino binds hp-IRAK1:TRAF6 (Homo sapiens)


name: NEMO subunit of IKK complex binds to activated IRAK1 (Homo sapiens)


name: Pellino ubiquitinates hp-IRAK1 (Homo sapiens)


name: IRAK1 phosphorylates Pellino (Homo sapiens)


name: IRAK1 recruits IKK complex (Mus musculus)


name: IRAK1 phosphorylates Pellino (Mus musculus)


name: Pellino binds hp-IRAK1:TRAF6 (Mus musculus)


name: Pellino ubiquitinates hp-IRAK1 (Mus musculus)


name: NEMO subunit of IKK complex binds to activated IRAK1 (Mus musculus)


name: IRAK1 recruits IKK complex (Rattus norvegicus)


name: NEMO subunit of IKK complex binds to activated IRAK1 (Rattus norvegicus)


name: Pellino binds hp-IRAK1:TRAF6 (Rattus norvegicus)


name: IRAK1 phosphorylates Pellino (Rattus norvegicus)


name: IRAK1 recruits IKK complex (Canis familiaris)


name: Pellino ubiquitinates hp-IRAK1 (Canis familiaris)


name: NEMO subunit of IKK complex binds to activated IRAK1 (Canis familiaris)


name: IRAK1 phosphorylates Pellino (Canis familiaris)


name: Pellino binds hp-IRAK1:TRAF6 (Canis familiaris)


name: NEMO subunit of IKK complex binds to activated IRAK1 (Bos taurus)


name: IRAK1 phosphorylates Pellino (Bos taurus)


name: Pellino binds hp-IRAK1:TRAF6 (Bos taurus)


name: IRAK1 phosphorylates Pellino (Sus scrofa)


name: Pellino binds hp-IRAK1:TRAF6 (Sus scrofa)


name: Pellino ubiquitinates hp-IRAK1 (Sus scrofa)


name: NEMO subunit of IKK complex binds to activated IRAK1 (Sus scrofa)


name: IRAK1 recruits IKK complex (Drosophila melanogaster)


name: Pellino ubiquitinates hp-IRAK1 (Drosophila melanogaster)


name: NEMO subunit of IKK complex binds to activated IRAK1 (Drosophila melanogaster)


name: Pellino binds hp-IRAK1:TRAF6 (Drosophila melanogaster)


name: IRAK1 phosphorylates Pellino (Drosophila melanogaster)


name: TAK1-dependent IKK and NF-kappa-B activation   (Homo sapiens)


name: Active IKBKB phosphorylates NF-kappa-B inhibitor  (Homo sapiens)


name: NF-kappa-B inhibitor binds NF-kappa-B complex (Homo sapiens)


name: Ubiquitination of IKBKG by TRAF6 (Homo sapiens)


name: CHUK, IKBKB and IKBKG form IKK complex (Homo sapiens)


name: Regulation of NF-kappa B signaling (Homo sapiens)


name: TP53 binds the IKBIP gene promoter (Homo sapiens)


name: CASP8 cleaves N4BP1 at D424, D490 (Homo sapiens)


name: NLRX1 binds CHUK:IKBKB:IKBKG (Homo sapiens)


name: TP53 stimulates IKBIP gene expression (Homo sapiens)


name: USP14 deubiquitinates NLRC5 (Homo sapiens)


name: TRAF2,6 ubiquitinates NLRC5 (Homo sapiens)


name: NLRC5 binds IKBKB and CHUK (Homo sapiens)


name: LRRC14 binds IKBKB and CHUK (Homo sapiens)


name: USP18 binds IKBKG within IKK complex (Homo sapiens)


name: IKBIP binds IKBKB and CHUK (Homo sapiens)


name: Regulation of NF-kappa B signaling (Mus musculus)


name: LRRC14 binds IKBKB and CHUK (Mus musculus)


name: CASP8 cleaves N4BP1 at D424, D490 (Mus musculus)


name: USP18 binds IKBKG within IKK complex (Mus musculus)


name: NLRC5 binds IKBKB and CHUK (Mus musculus)


name: TRAF2,6 ubiquitinates NLRC5 (Mus musculus)


name: NLRX1 binds CHUK:IKBKB:IKBKG (Mus musculus)


name: USP14 deubiquitinates NLRC5 (Mus musculus)


name: Regulation of NF-kappa B signaling (Rattus norvegicus)


name: CASP8 cleaves N4BP1 at D424, D490 (Rattus norvegicus)


name: TRAF2,6 ubiquitinates NLRC5 (Rattus norvegicus)


name: USP18 binds IKBKG within IKK complex (Rattus norvegicus)


name: USP14 deubiquitinates NLRC5 (Rattus norvegicus)


name: NLRX1 binds CHUK:IKBKB:IKBKG (Rattus norvegicus)


name: NLRC5 binds IKBKB and CHUK (Rattus norvegicus)


name: LRRC14 binds IKBKB and CHUK (Rattus norvegicus)


name: Regulation of NF-kappa B signaling (Canis familiaris)


name: TRAF2,6 ubiquitinates NLRC5 (Canis familiaris)


name: USP18 binds IKBKG within IKK complex (Canis familiaris)


name: LRRC14 binds IKBKB and CHUK (Canis familiaris)


name: NLRC5 binds IKBKB and CHUK (Canis familiaris)


name: NLRX1 binds CHUK:IKBKB:IKBKG (Canis familiaris)


name: USP14 deubiquitinates NLRC5 (Canis familiaris)


name: CASP8 cleaves N4BP1 at D424, D490 (Canis familiaris)


name: Regulation of NF-kappa B signaling (Bos taurus)


name: USP18 binds IKBKG within IKK complex (Bos taurus)


name: USP14 deubiquitinates NLRC5 (Bos taurus)


name: TRAF2,6 ubiquitinates NLRC5 (Bos taurus)


name: CASP8 cleaves N4BP1 at D424, D490 (Bos taurus)


name: NLRX1 binds CHUK:IKBKB:IKBKG (Bos taurus)


name: LRRC14 binds IKBKB and CHUK (Bos taurus)


name: Regulation of NF-kappa B signaling (Sus scrofa)


name: USP14 deubiquitinates NLRC5 (Sus scrofa)


name: LRRC14 binds IKBKB and CHUK (Sus scrofa)


name: TRAF2,6 ubiquitinates NLRC5 (Sus scrofa)


name: CASP8 cleaves N4BP1 at D424, D490 (Sus scrofa)


name: USP18 binds IKBKG within IKK complex (Sus scrofa)


name: Regulation of NF-kappa B signaling (Danio rerio)


name: CASP8 cleaves N4BP1 at D424, D490 (Danio rerio)


name: Regulation of NF-kappa B signaling (Xenopus tropicalis)


name: USP14 deubiquitinates NLRC5 (Xenopus tropicalis)


name: Regulation of NF-kappa B signaling (Gallus gallus)


name: CASP8 cleaves N4BP1 at D424, D490 (Gallus gallus)


name: NLRC5 binds IKBKB and CHUK (Gallus gallus)


name: TRAF2,6 ubiquitinates NLRC5 (Gallus gallus)


name: USP14 deubiquitinates NLRC5 (Gallus gallus)


name: Regulation of NF-kappa B signaling (Drosophila melanogaster)


name: USP18 binds IKBKG within IKK complex (Drosophila melanogaster)


name: N4BP1 binds IKBKG (Drosophila melanogaster)


name: Regulation of NF-kappa B signaling (Dictyostelium discoideum)


name: USP14 deubiquitinates NLRC5 (Dictyostelium discoideum)


name: TAK1-dependent IKK and NF-kappa-B activation   (Mus musculus)


name: CHUK, IKBKB and IKBKG form IKK complex (Mus musculus)


name: Ubiquitination of IKBKG by TRAF6 (Mus musculus)


name: Active IKBKB phosphorylates NF-kappa-B inhibitor  (Mus musculus)


name: NF-kappa-B inhibitor binds NF-kappa-B complex (Mus musculus)


name: TAK1-dependent IKK and NF-kappa-B activation   (Rattus norvegicus)


name: Active IKBKB phosphorylates NF-kappa-B inhibitor  (Rattus norvegicus)


name: CHUK, IKBKB and IKBKG form IKK complex (Rattus norvegicus)


name: NF-kappa-B inhibitor binds NF-kappa-B complex (Rattus norvegicus)


name: TAK1-dependent IKK and NF-kappa-B activation   (Canis familiaris)


name: CHUK, IKBKB and IKBKG form IKK complex (Canis familiaris)


name: Active IKBKB phosphorylates NF-kappa-B inhibitor  (Canis familiaris)


name: NF-kappa-B inhibitor binds NF-kappa-B complex (Canis familiaris)


name: Ubiquitination of IKBKG by TRAF6 (Canis familiaris)


name: TAK1-dependent IKK and NF-kappa-B activation   (Bos taurus)


name: NF-kappa-B inhibitor binds NF-kappa-B complex (Bos taurus)


name: CHUK, IKBKB and IKBKG form IKK complex (Bos taurus)


name: Active IKBKB phosphorylates NF-kappa-B inhibitor  (Bos taurus)


name: TAK1-dependent IKK and NF-kappa-B activation   (Sus scrofa)


name: CHUK, IKBKB and IKBKG form IKK complex (Sus scrofa)


name: Active IKBKB phosphorylates NF-kappa-B inhibitor  (Sus scrofa)


name: Ubiquitination of IKBKG by TRAF6 (Sus scrofa)


name: NF-kappa-B inhibitor binds NF-kappa-B complex (Sus scrofa)


name: TAK1-dependent IKK and NF-kappa-B activation   (Danio rerio)


name: NF-kappa-B inhibitor binds NF-kappa-B complex (Danio rerio)


name: TAK1-dependent IKK and NF-kappa-B activation   (Gallus gallus)


name: NF-kappa-B inhibitor binds NF-kappa-B complex (Gallus gallus)


name: TAK1-dependent IKK and NF-kappa-B activation   (Drosophila melanogaster)


name: NF-kappa-B inhibitor binds NF-kappa-B complex (Drosophila melanogaster)


name: Ubiquitination of IKBKG by TRAF6 (Drosophila melanogaster)


name: Active IKBKB phosphorylates NF-kappa-B inhibitor  (Drosophila melanogaster)


name: CHUK, IKBKB and IKBKG form IKK complex (Drosophila melanogaster)


name: JNK (c-Jun kinases) phosphorylation and  activation mediated by activated human TAK1 (Homo sapiens)


name: Activated human JNKs migrate to nucleoplasm (Homo sapiens)


name: Activated TAK1 phosphorylates MKK4/MKK7 (Homo sapiens)


JUN kinase kinase activity

description: Catalysis of the phosphorylation of tyrosine and threonine residues in a c-Jun NH2-terminal kinase (JNK), a member of a subgroup of mitogen-activated protein kinases (MAPKs), which signal in response to cytokines and exposure to environmental stress. JUN kinase kinase (JNKK) is a dual-specificity protein kinase kinase and requires activation by a serine/threonine kinase JUN kinase kinase kinase.


name: JNK (c-Jun kinases) phosphorylation and  activation mediated by activated human TAK1 (Mus musculus)


name: Phosphorylation of human JNKs by activated MKK4/MKK7 (Mus musculus)


name: Activated TAK1 phosphorylates MKK4/MKK7 (Mus musculus)


name: Activated human JNKs migrate to nucleoplasm (Mus musculus)


name: JNK (c-Jun kinases) phosphorylation and  activation mediated by activated human TAK1 (Rattus norvegicus)


name: Activated TAK1 phosphorylates MKK4/MKK7 (Rattus norvegicus)


name: Activated human JNKs migrate to nucleoplasm (Rattus norvegicus)


name: Phosphorylation of human JNKs by activated MKK4/MKK7 (Rattus norvegicus)


name: JNK (c-Jun kinases) phosphorylation and  activation mediated by activated human TAK1 (Canis familiaris)


name: Phosphorylation of human JNKs by activated MKK4/MKK7 (Canis familiaris)


name: Activated human JNKs migrate to nucleoplasm (Canis familiaris)


name: Activated TAK1 phosphorylates MKK4/MKK7 (Canis familiaris)


name: JNK (c-Jun kinases) phosphorylation and  activation mediated by activated human TAK1 (Bos taurus)


name: Activated human JNKs migrate to nucleoplasm (Bos taurus)


name: Phosphorylation of human JNKs by activated MKK4/MKK7 (Bos taurus)


name: Activated TAK1 phosphorylates MKK4/MKK7 (Bos taurus)


name: JNK (c-Jun kinases) phosphorylation and  activation mediated by activated human TAK1 (Sus scrofa)


name: Activated human JNKs migrate to nucleoplasm (Sus scrofa)


name: Phosphorylation of human JNKs by activated MKK4/MKK7 (Sus scrofa)


name: Activated TAK1 phosphorylates MKK4/MKK7 (Sus scrofa)


name: JNK (c-Jun kinases) phosphorylation and  activation mediated by activated human TAK1 (Danio rerio)


name: Activated human JNKs migrate to nucleoplasm (Danio rerio)


name: Phosphorylation of human JNKs by activated MKK4/MKK7 (Danio rerio)


name: JNK (c-Jun kinases) phosphorylation and  activation mediated by activated human TAK1 (Xenopus tropicalis)


name: Activated TAK1 phosphorylates MKK4/MKK7 (Xenopus tropicalis)


name: JNK (c-Jun kinases) phosphorylation and  activation mediated by activated human TAK1 (Gallus gallus)


name: Phosphorylation of human JNKs by activated MKK4/MKK7 (Gallus gallus)


name: Activated TAK1 phosphorylates MKK4/MKK7 (Gallus gallus)


name: Activated human JNKs migrate to nucleoplasm (Gallus gallus)


name: JNK (c-Jun kinases) phosphorylation and  activation mediated by activated human TAK1 (Drosophila melanogaster)


name: Phosphorylation of human JNKs by activated MKK4/MKK7 (Drosophila melanogaster)


name: Activated TAK1 phosphorylates MKK4/MKK7 (Drosophila melanogaster)


name: Activated human JNKs migrate to nucleoplasm (Drosophila melanogaster)


name: JNK (c-Jun kinases) phosphorylation and  activation mediated by activated human TAK1 (Caenorhabditis elegans)


name: Activated human JNKs migrate to nucleoplasm (Caenorhabditis elegans)


name: Phosphorylation of human JNKs by activated MKK4/MKK7 (Caenorhabditis elegans)


name: JNK (c-Jun kinases) phosphorylation and  activation mediated by activated human TAK1 (Dictyostelium discoideum)


name: Phosphorylation of human JNKs by activated MKK4/MKK7 (Dictyostelium discoideum)


name: Activated human JNKs migrate to nucleoplasm (Dictyostelium discoideum)


name: JNK (c-Jun kinases) phosphorylation and  activation mediated by activated human TAK1 (Schizosaccharomyces pombe)


name: Activated human JNKs migrate to nucleoplasm (Schizosaccharomyces pombe)


name: JNK (c-Jun kinases) phosphorylation and  activation mediated by activated human TAK1 (Saccharomyces cerevisiae)


name: Activated human JNKs migrate to nucleoplasm (Saccharomyces cerevisiae)


name: activated TAK1 mediates p38 MAPK activation (Homo sapiens)


name: Phosphorylated MKK3/MKK6 migrates to nucleus (Homo sapiens)


name: activated human TAK1 phosphorylates MKK3/MKK6 (Homo sapiens)


name: Activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK2 or MAPKAPK3 (Homo sapiens)


name: Active p38 MAPK phosphorylates MAPKAPK2 or 3 (Homo sapiens)


name: Nuclear export of human p38 MAPK mediated by its substrate MAPKAPK2 or 3 (Homo sapiens)


name: activated TAK1 mediates p38 MAPK activation (Mus musculus)


name: Nuclear export of human p38 MAPK mediated by its substrate MAPKAPK2 or 3 (Mus musculus)


name: Activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK2 or MAPKAPK3 (Mus musculus)


name: activated human TAK1 phosphorylates MKK3/MKK6 (Mus musculus)


name: Active p38 MAPK phosphorylates MAPKAPK2 or 3 (Mus musculus)


name: Phosphorylated MKK3/MKK6 migrates to nucleus (Mus musculus)


name: activated TAK1 mediates p38 MAPK activation (Rattus norvegicus)


name: activated human TAK1 phosphorylates MKK3/MKK6 (Rattus norvegicus)


name: Phosphorylated MKK3/MKK6 migrates to nucleus (Rattus norvegicus)


name: Activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK2 or MAPKAPK3 (Rattus norvegicus)


name: Nuclear export of human p38 MAPK mediated by its substrate MAPKAPK2 or 3 (Rattus norvegicus)


name: Active p38 MAPK phosphorylates MAPKAPK2 or 3 (Rattus norvegicus)


name: activated TAK1 mediates p38 MAPK activation (Canis familiaris)


name: activated human TAK1 phosphorylates MKK3/MKK6 (Canis familiaris)


name: Phosphorylated MKK3/MKK6 migrates to nucleus (Canis familiaris)


name: activated TAK1 mediates p38 MAPK activation (Bos taurus)


name: Phosphorylated MKK3/MKK6 migrates to nucleus (Bos taurus)


name: Activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK2 or MAPKAPK3 (Bos taurus)


name: Nuclear export of human p38 MAPK mediated by its substrate MAPKAPK2 or 3 (Bos taurus)


name: activated human TAK1 phosphorylates MKK3/MKK6 (Bos taurus)


name: Active p38 MAPK phosphorylates MAPKAPK2 or 3 (Bos taurus)


name: activated TAK1 mediates p38 MAPK activation (Sus scrofa)


name: Active p38 MAPK phosphorylates MAPKAPK2 or 3 (Sus scrofa)


name: Nuclear export of human p38 MAPK mediated by its substrate MAPKAPK2 or 3 (Sus scrofa)


name: Phosphorylated MKK3/MKK6 migrates to nucleus (Sus scrofa)


name: Activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK2 or MAPKAPK3 (Sus scrofa)


name: activated human TAK1 phosphorylates MKK3/MKK6 (Sus scrofa)


name: activated TAK1 mediates p38 MAPK activation (Danio rerio)


name: Activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK2 or MAPKAPK3 (Danio rerio)


name: Phosphorylated MKK3/MKK6 migrates to nucleus (Danio rerio)


name: Nuclear export of human p38 MAPK mediated by its substrate MAPKAPK2 or 3 (Danio rerio)


name: Active p38 MAPK phosphorylates MAPKAPK2 or 3 (Danio rerio)


name: activated TAK1 mediates p38 MAPK activation (Xenopus tropicalis)


name: Phosphorylated MKK3/MKK6 migrates to nucleus (Xenopus tropicalis)


name: activated human TAK1 phosphorylates MKK3/MKK6 (Xenopus tropicalis)


name: activated TAK1 mediates p38 MAPK activation (Gallus gallus)


name: Nuclear export of human p38 MAPK mediated by its substrate MAPKAPK2 or 3 (Gallus gallus)


name: Phosphorylated MKK3/MKK6 migrates to nucleus (Gallus gallus)


name: activated human TAK1 phosphorylates MKK3/MKK6 (Gallus gallus)


name: Activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK2 or MAPKAPK3 (Gallus gallus)


name: Active p38 MAPK phosphorylates MAPKAPK2 or 3 (Gallus gallus)


name: activated TAK1 mediates p38 MAPK activation (Drosophila melanogaster)


name: Activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK2 or MAPKAPK3 (Drosophila melanogaster)


name: Phosphorylated MKK3/MKK6 migrates to nucleus (Drosophila melanogaster)


name: Nuclear export of human p38 MAPK mediated by its substrate MAPKAPK2 or 3 (Drosophila melanogaster)


name: activated human TAK1 phosphorylates MKK3/MKK6 (Drosophila melanogaster)


name: Active p38 MAPK phosphorylates MAPKAPK2 or 3 (Drosophila melanogaster)


name: activated TAK1 mediates p38 MAPK activation (Caenorhabditis elegans)


name: Active p38 MAPK phosphorylates MAPKAPK2 or 3 (Caenorhabditis elegans)


name: Nuclear export of human p38 MAPK mediated by its substrate MAPKAPK2 or 3 (Caenorhabditis elegans)


name: Phosphorylated MKK3/MKK6 migrates to nucleus (Caenorhabditis elegans)


name: Activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK2 or MAPKAPK3 (Caenorhabditis elegans)


name: activated TAK1 mediates p38 MAPK activation (Dictyostelium discoideum)


name: Phosphorylated MKK3/MKK6 migrates to nucleus (Dictyostelium discoideum)


name: p38MAPK phosphorylates MSK1 (Homo sapiens)


name: ERK5 activates the transcription factor MEF2 (Homo sapiens)


name: ERK1/2/5 activate RSK1/2/3 (Homo sapiens)


name: ERK1/2 phosphorylates MSK1 (Homo sapiens)


name: ERKs are inactivated by protein phosphatase 2A (Homo sapiens)


name: ERKs are inactivated by dual-specific phosphatases (DUSPs) (Homo sapiens)


name: ERKs are inactivated by dual-specific phosphatases (DUSPs) (Mus musculus)


name: ERKs are inactivated by protein phosphatase 2A (Mus musculus)


name: ERKs are inactivated (Rattus norvegicus)


name: ERKs are inactivated by dual-specific phosphatases (DUSPs) (Rattus norvegicus)


name: ERKs are inactivated by protein phosphatase 2A (Rattus norvegicus)


name: ERKs are inactivated by protein phosphatase 2A (Canis familiaris)


name: ERKs are inactivated by dual-specific phosphatases (DUSPs) (Canis familiaris)


name: ERKs are inactivated by protein phosphatase 2A (Bos taurus)


name: ERKs are inactivated by dual-specific phosphatases (DUSPs) (Bos taurus)


name: ERKs are inactivated by protein phosphatase 2A (Sus scrofa)


name: ERKs are inactivated by dual-specific phosphatases (DUSPs) (Sus scrofa)


name: ERKs are inactivated by dual-specific phosphatases (DUSPs) (Danio rerio)


name: ERKs are inactivated by protein phosphatase 2A (Danio rerio)


name: ERKs are inactivated (Xenopus tropicalis)


name: ERKs are inactivated by dual-specific phosphatases (DUSPs) (Xenopus tropicalis)


name: ERKs are inactivated by dual-specific phosphatases (DUSPs) (Gallus gallus)


name: ERKs are inactivated (Drosophila melanogaster)


name: ERKs are inactivated by dual-specific phosphatases (DUSPs) (Drosophila melanogaster)


name: ERKs are inactivated by protein phosphatase 2A (Drosophila melanogaster)


name: ERKs are inactivated (Caenorhabditis elegans)


name: ERKs are inactivated by dual-specific phosphatases (DUSPs) (Caenorhabditis elegans)


name: ERKs are inactivated by protein phosphatase 2A (Caenorhabditis elegans)


name: ERKs are inactivated (Dictyostelium discoideum)


name: ERKs are inactivated by dual-specific phosphatases (DUSPs) (Dictyostelium discoideum)


name: ERKs are inactivated by protein phosphatase 2A (Dictyostelium discoideum)


name: ERKs are inactivated (Schizosaccharomyces pombe)


name: ERKs are inactivated by protein phosphatase 2A (Schizosaccharomyces pombe)


name: ERKs are inactivated (Saccharomyces cerevisiae)


name: ERKs are inactivated by protein phosphatase 2A (Saccharomyces cerevisiae)


name: ERKs are inactivated (Plasmodium falciparum)


name: ERKs are inactivated by dual-specific phosphatases (DUSPs) (Plasmodium falciparum)


name: ERK1/2/5 activate RSK1/2/3 (Mus musculus)


name: p38MAPK phosphorylates MSK1 (Mus musculus)


name: ERK1/2 phosphorylates MSK1 (Mus musculus)


name: p38MAPK phosphorylates MSK1 (Rattus norvegicus)


name: ERK1/2 phosphorylates MSK1 (Rattus norvegicus)


name: ERK1/2/5 activate RSK1/2/3 (Rattus norvegicus)


name: ERK1/2/5 activate RSK1/2/3 (Canis familiaris)


name: p38MAPK phosphorylates MSK1 (Canis familiaris)


name: ERK1/2 phosphorylates MSK1 (Canis familiaris)


name: p38MAPK phosphorylates MSK1 (Bos taurus)


name: p38MAPK phosphorylates MSK1 (Sus scrofa)


name: ERK1/2/5 activate RSK1/2/3 (Xenopus tropicalis)


name: p38MAPK phosphorylates MSK1 (Gallus gallus)


name: ERK1/2 phosphorylates MSK1 (Gallus gallus)


name: ERK1/2/5 activate RSK1/2/3 (Gallus gallus)


name: ERK/MAPK targets (Drosophila melanogaster)


name: ERK1/2/5 activate RSK1/2/3 (Drosophila melanogaster)


name: p38MAPK phosphorylates MSK1 (Drosophila melanogaster)


name: ERK1/2 phosphorylates MSK1 (Drosophila melanogaster)


name: ERK/MAPK targets (Caenorhabditis elegans)


name: ERK1/2/5 activate RSK1/2/3 (Caenorhabditis elegans)


name: p38MAPK phosphorylates MSK1 (Caenorhabditis elegans)


name: ERK1/2 phosphorylates MSK1 (Caenorhabditis elegans)


name: ERK/MAPK targets (Dictyostelium discoideum)


name: ERK1/2/5 activate RSK1/2/3 (Dictyostelium discoideum)


name: ERK1/2 phosphorylates MSK1 (Dictyostelium discoideum)


name: p38MAPK phosphorylates MSK1 (Dictyostelium discoideum)


name: ERK/MAPK targets (Schizosaccharomyces pombe)


name: ERK1/2/5 activate RSK1/2/3 (Schizosaccharomyces pombe)


name: p38MAPK phosphorylates MSK1 (Schizosaccharomyces pombe)


name: ERK1/2 phosphorylates MSK1 (Schizosaccharomyces pombe)


name: ERK/MAPK targets (Saccharomyces cerevisiae)


name: p38MAPK phosphorylates MSK1 (Saccharomyces cerevisiae)


name: ERK1/2/5 activate RSK1/2/3 (Saccharomyces cerevisiae)


name: ERK1/2 phosphorylates MSK1 (Saccharomyces cerevisiae)


name: MAPKAPK2 phosphorylates CREB at Serine 133 (Homo sapiens)


name: RSK1/2/3 phosphorylates CREB at Serine 119 (Homo sapiens)


name: MAPKAPK2 phosphorylates CREB at Serine 133 (Mus musculus)


name: RSK1/2/3 phosphorylates CREB at Serine 119 (Mus musculus)


name: CREB phosphorylation (Rattus norvegicus)


name: MAPKAPK2 phosphorylates CREB at Serine 133 (Rattus norvegicus)


name: RSK1/2/3 phosphorylates CREB at Serine 119 (Rattus norvegicus)


name: RSK1/2/3 phosphorylates CREB at Serine 119 (Canis familiaris)


name: RSK1/2/3 phosphorylates CREB at Serine 119 (Bos taurus)


name: MAPKAPK2 phosphorylates CREB at Serine 133 (Bos taurus)


name: MAPKAPK2 phosphorylates CREB at Serine 133 (Sus scrofa)


name: RSK1/2/3 phosphorylates CREB at Serine 119 (Sus scrofa)


name: MAPKAPK2 phosphorylates CREB at Serine 133 (Danio rerio)


name: CREB phosphorylation (Xenopus tropicalis)


name: RSK1/2/3 phosphorylates CREB at Serine 119 (Xenopus tropicalis)


name: RSK1/2/3 phosphorylates CREB at Serine 119 (Gallus gallus)


name: MAPKAPK2 phosphorylates CREB at Serine 133 (Gallus gallus)


name: CREB phosphorylation (Drosophila melanogaster)


name: MSK1 activates ATF1 (Drosophila melanogaster)


name: MSK1 activates CREB (Drosophila melanogaster)


name: RSK1/2/3 phosphorylates CREB at Serine 119 (Drosophila melanogaster)


name: MAPKAPK2 phosphorylates CREB at Serine 133 (Drosophila melanogaster)


name: CREB phosphorylation (Caenorhabditis elegans)


name: MSK1 activates CREB (Caenorhabditis elegans)


name: MAPKAPK2 phosphorylates CREB at Serine 133 (Caenorhabditis elegans)