chaperone-mediated autophagy

category: biolink:BiologicalProcess biolink:Occurrent biolink:OntologyClass biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: The autophagy process which begins when chaperones and co-chaperones recognize a target motif and unfold the substrate protein. The proteins are then transported to the lysosome where they are degraded.


name: HSPA8 binds LAMP2a multimers (Homo sapiens)

category: biolink:MolecularActivity biolink:Occurrent biolink:OntologyClass biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent


name: GFAP binds LAMP2a multimer (Homo sapiens)


name: HSPA8:Substrate dissociates from LAMP2a multimer (Homo sapiens)


name: Unfolded substrate in LAMP2a multimeric complex binds HSPA8 (Homo sapiens)


name: Substrate:LAMP2a binds HSP90 (Homo sapiens)


name: HSPA8:Substrate binds LAMP2a (Homo sapiens)


name: HSP90 dissociates from LAMP2a (Homo sapiens)


name: HSPA8 transports unfolded substrate to lysosomal lumen for degradation (Homo sapiens)


name: p-GFAP:GFAP dissociates from LAMP2a multimer (Homo sapiens)


name: Substrate:LAMP2a:HSP90 polymerizes (Homo sapiens)


name: HSPA8 dissociates from LAMP2A-bound substrate (Homo sapiens)


name: HSPA8 dissociates from LAMP2a (Homo sapiens)


name: pGFAP binds GFAP in LAMP2a multimer (Homo sapiens)


name: HSPA8:LAMP2a multimers depolymerizes to monomers (Homo sapiens)


name: EEF1A1:GTP translocates from lysosomal membrane to cytosol (Homo sapiens)


name: EEF1A1 dissociates from p-GFAP (Homo sapiens)


macroautophagy

description: The autophagic process that proceeds via the formation of an autophagosome.


name: ULK1 phosphorylates AMBRA1:BECN1 complex (Homo sapiens)


name: ATG12 forms a thioester bond with ATG7 dimer (Homo sapiens)


name: WIPI2 binds ATG12:ATG5:ATG16L (Homo sapiens)


name: LC3:ATG7 dimer binds ATG3 (Homo sapiens)


name: Rheb in the MTORC1 complex hydrolyses GTP (Homo sapiens)


name: The phagophore extends from the PIP3-enriched structure (Homo sapiens)


name: ULK1 phosphorylates ATG13 and RB1CC1 (Homo sapiens)


name: ATG16L1 complex transfers LC3 from ATG3 to PE (Homo sapiens)


name: ULK complex translocates to the ER (Homo sapiens)


name: ATG10 transfers ATG12 from ATG10 to ATG5 (Homo sapiens)


name: AMBRA1 binds DYNLL1,DYNLL2 (Homo sapiens)


name: ATG10 dissociates from ATG12:ATG5 (Homo sapiens)


name: MTORC1 dissociates from ULK complex (Homo sapiens)


Atg12 transferase activity

description: Catalysis of the transfer of ATG12 from one protein to another via the reaction X-ATG12 + Y = Y-ATG12 + X, where both X-ATG12 and Y-ATG12 are covalent linkages.


name: AMPK (complex) phosphorylates ULK1 (complex) (Homo sapiens)


name: Beclin-1 complex phosphorylates PtdIns (Homo sapiens)


name: ATG12:ATG7:CysO572-ATG7 binds ATG10 (Homo sapiens)


name: Active MTORC1 phosphorylates ULK1 (Homo sapiens)


name: p-AMPK:AMP binds the ULK complex (Homo sapiens)


name: Thr-180 of ULK1 is phosphorylated (Homo sapiens)


name: ATG7:ATG3:LC3 dissociates (Homo sapiens)


name: LC3 de-lipidation by ATG4 (Homo sapiens)


name: Active MTORC1 binds the ULK1 complex (Homo sapiens)


name: ATG10:ATG12:ATG7 dimer dissociates (Homo sapiens)


Atg8-family ligase activity

description: Catalysis of the covalent attachment of the ubiquitin-like protein Atg8 family modifier to phosphatidylethanolamine or phosphatidylserine on a membrane.


name: MTMR14, MTMR3 dephosphorylate PI3P (Homo sapiens)


name: ULK1 phosphorylates Beclin-1 (Homo sapiens)


name: Beclin-1 complex translocates to the ER (Homo sapiens)


name: BECN1 complex, p-AMBRA1 dissociate from DYNLL1,DYNLL2 (Homo sapiens)


name: p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex (Homo sapiens)


name: AMBRA1:DYNLL1,DYNLL2 binds BECN1 complex (Homo sapiens)


name: PINK1-PRKN Mediated Mitophagy (Homo sapiens)

category: biolink:Pathway biolink:OntologyClass biolink:BiologicalProcess biolink:Occurrent biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent


name: PRKN ubiquitinates MOM substrates (Homo sapiens)


name: p62 binds ubiquitinated mitochondrial substrates (Homo sapiens)


name: Uncleaved Pink1 accumulates in damaged mitochondria (Homo sapiens)


name: MAP1LC3B binds p-S-OPTN bound to Ub-mitochondria  (Homo sapiens)


name: PINK1 is autophosphorylated (Homo sapiens)


name: TBK1 is phosphorylated within TBK1:OPTN:Ub-mitochondrial proteins (Homo sapiens)


name: OPTN, TBK1 bind ubiquitinated MOM proteins (Homo sapiens)


name: LC3 binds the autophagosome membrane Atg5-Atg12 complex (Homo sapiens)


name: Pink1 is recruited from the cytoplasm to the mitochondria (Homo sapiens)


name: p-S-TBK1 phosphorylates OPTN (Homo sapiens)


name: PINK1 phosphorylates PRKN at S65 (Homo sapiens)


name: PINK1 phosphorylates Ub on MOM proteins (Homo sapiens)


name: PRKN binds p-S-Ub:MOM proteins (Homo sapiens)


name: Pink1 is cleaved on healthy mitochondria (Homo sapiens)


name: p62 links damaged mitochondria to LC3 (Homo sapiens)


name: PINK1-PRKN Mediated Mitophagy (Mus musculus)


name: MAP1LC3B binds p-S-OPTN bound to Ub-mitochondria  (Mus musculus)


name: PRKN binds p-S-Ub:MOM proteins (Mus musculus)


name: PRKN ubiquitinates MOM substrates (Mus musculus)


name: PINK1 phosphorylates Ub on MOM proteins (Mus musculus)


name: Uncleaved Pink1 accumulates in damaged mitochondria (Mus musculus)


name: p-S-TBK1 phosphorylates OPTN (Mus musculus)


name: PINK1 is autophosphorylated (Mus musculus)


name: TBK1 is phosphorylated within TBK1:OPTN:Ub-mitochondrial proteins (Mus musculus)


name: LC3 binds the autophagosome membrane Atg5-Atg12 complex (Mus musculus)


name: PINK1 phosphorylates PRKN at S65 (Mus musculus)


name: Pink1 is cleaved on healthy mitochondria (Mus musculus)


name: p62 binds ubiquitinated mitochondrial substrates (Mus musculus)


name: Pink1 is recruited from the cytoplasm to the mitochondria (Mus musculus)


name: OPTN, TBK1 bind ubiquitinated MOM proteins (Mus musculus)


name: p62 links damaged mitochondria to LC3 (Mus musculus)


name: PINK1-PRKN Mediated Mitophagy (Rattus norvegicus)


name: p-S-TBK1 phosphorylates OPTN (Rattus norvegicus)


name: PINK1 phosphorylates PRKN at S65 (Rattus norvegicus)


name: Uncleaved Pink1 accumulates in damaged mitochondria (Rattus norvegicus)


name: LC3 binds the autophagosome membrane Atg5-Atg12 complex (Rattus norvegicus)


name: PINK1 is autophosphorylated (Rattus norvegicus)


name: Pink1 is cleaved on healthy mitochondria (Rattus norvegicus)


name: PINK1 phosphorylates Ub on MOM proteins (Rattus norvegicus)


name: p62 links damaged mitochondria to LC3 (Rattus norvegicus)


name: p62 binds ubiquitinated mitochondrial substrates (Rattus norvegicus)


name: OPTN, TBK1 bind ubiquitinated MOM proteins (Rattus norvegicus)


name: TBK1 is phosphorylated within TBK1:OPTN:Ub-mitochondrial proteins (Rattus norvegicus)


name: PRKN binds p-S-Ub:MOM proteins (Rattus norvegicus)


name: MAP1LC3B binds p-S-OPTN bound to Ub-mitochondria  (Rattus norvegicus)


name: Pink1 is recruited from the cytoplasm to the mitochondria (Rattus norvegicus)


name: PINK1-PRKN Mediated Mitophagy (Canis familiaris)


name: p-S-TBK1 phosphorylates OPTN (Canis familiaris)


name: PRKN ubiquitinates MOM substrates (Canis familiaris)


name: Pink1 is recruited from the cytoplasm to the mitochondria (Canis familiaris)


name: PINK1 is autophosphorylated (Canis familiaris)


name: OPTN, TBK1 bind ubiquitinated MOM proteins (Canis familiaris)


name: PINK1 phosphorylates Ub on MOM proteins (Canis familiaris)


name: Uncleaved Pink1 accumulates in damaged mitochondria (Canis familiaris)


name: p62 binds ubiquitinated mitochondrial substrates (Canis familiaris)


name: LC3 binds the autophagosome membrane Atg5-Atg12 complex (Canis familiaris)


name: PRKN binds p-S-Ub:MOM proteins (Canis familiaris)


name: MAP1LC3B binds p-S-OPTN bound to Ub-mitochondria  (Canis familiaris)


name: PINK1 phosphorylates PRKN at S65 (Canis familiaris)


name: p62 links damaged mitochondria to LC3 (Canis familiaris)


name: TBK1 is phosphorylated within TBK1:OPTN:Ub-mitochondrial proteins (Canis familiaris)


name: Pink1 is cleaved on healthy mitochondria (Canis familiaris)


name: PINK1-PRKN Mediated Mitophagy (Bos taurus)


name: Pink1 is recruited from the cytoplasm to the mitochondria (Bos taurus)


name: PINK1 phosphorylates Ub on MOM proteins (Bos taurus)


name: MAP1LC3B binds p-S-OPTN bound to Ub-mitochondria  (Bos taurus)


name: PRKN binds p-S-Ub:MOM proteins (Bos taurus)


name: TBK1 is phosphorylated within TBK1:OPTN:Ub-mitochondrial proteins (Bos taurus)


name: p-S-TBK1 phosphorylates OPTN (Bos taurus)


name: PINK1 phosphorylates PRKN at S65 (Bos taurus)


name: LC3 binds the autophagosome membrane Atg5-Atg12 complex (Bos taurus)


name: p62 binds ubiquitinated mitochondrial substrates (Bos taurus)


name: Uncleaved Pink1 accumulates in damaged mitochondria (Bos taurus)


name: PINK1 is autophosphorylated (Bos taurus)


name: Pink1 is cleaved on healthy mitochondria (Bos taurus)


name: p62 links damaged mitochondria to LC3 (Bos taurus)


name: OPTN, TBK1 bind ubiquitinated MOM proteins (Bos taurus)


name: PINK1-PRKN Mediated Mitophagy (Sus scrofa)


name: MAP1LC3B binds p-S-OPTN bound to Ub-mitochondria  (Sus scrofa)


name: Pink1 is cleaved on healthy mitochondria (Sus scrofa)


name: TBK1 is phosphorylated within TBK1:OPTN:Ub-mitochondrial proteins (Sus scrofa)


name: p62 links damaged mitochondria to LC3 (Sus scrofa)


name: p-S-TBK1 phosphorylates OPTN (Sus scrofa)


name: PINK1 phosphorylates Ub on MOM proteins (Sus scrofa)


name: Pink1 is recruited from the cytoplasm to the mitochondria (Sus scrofa)


name: OPTN, TBK1 bind ubiquitinated MOM proteins (Sus scrofa)


name: LC3 binds the autophagosome membrane Atg5-Atg12 complex (Sus scrofa)


name: Uncleaved Pink1 accumulates in damaged mitochondria (Sus scrofa)


name: p62 binds ubiquitinated mitochondrial substrates (Sus scrofa)


name: PINK1 is autophosphorylated (Sus scrofa)


name: PINK1-PRKN Mediated Mitophagy (Danio rerio)


name: OPTN, TBK1 bind ubiquitinated MOM proteins (Danio rerio)


name: PINK1 phosphorylates PRKN at S65 (Danio rerio)


name: PRKN binds p-S-Ub:MOM proteins (Danio rerio)


name: PRKN ubiquitinates MOM substrates (Danio rerio)


name: PINK1 phosphorylates Ub on MOM proteins (Danio rerio)


name: p-S-TBK1 phosphorylates OPTN (Danio rerio)


name: TBK1 is phosphorylated within TBK1:OPTN:Ub-mitochondrial proteins (Danio rerio)


name: p62 links damaged mitochondria to LC3 (Danio rerio)


name: Pink1 is cleaved on healthy mitochondria (Danio rerio)


name: MAP1LC3B binds p-S-OPTN bound to Ub-mitochondria  (Danio rerio)


name: p62 binds ubiquitinated mitochondrial substrates (Danio rerio)


name: Uncleaved Pink1 accumulates in damaged mitochondria (Danio rerio)


name: PINK1 is autophosphorylated (Danio rerio)


name: LC3 binds the autophagosome membrane Atg5-Atg12 complex (Danio rerio)


name: PINK1-PRKN Mediated Mitophagy (Xenopus tropicalis)


name: TBK1 is phosphorylated within TBK1:OPTN:Ub-mitochondrial proteins (Xenopus tropicalis)


name: OPTN, TBK1 bind ubiquitinated MOM proteins (Xenopus tropicalis)


name: p-S-TBK1 phosphorylates OPTN (Xenopus tropicalis)


name: p62 links damaged mitochondria to LC3 (Xenopus tropicalis)


name: p62 binds ubiquitinated mitochondrial substrates (Xenopus tropicalis)


name: LC3 binds the autophagosome membrane Atg5-Atg12 complex (Xenopus tropicalis)


name: PINK1-PRKN Mediated Mitophagy (Gallus gallus)


name: PRKN binds p-S-Ub:MOM proteins (Gallus gallus)


name: p-S-TBK1 phosphorylates OPTN (Gallus gallus)


name: TBK1 is phosphorylated within TBK1:OPTN:Ub-mitochondrial proteins (Gallus gallus)


name: OPTN, TBK1 bind ubiquitinated MOM proteins (Gallus gallus)


name: MAP1LC3B binds p-S-OPTN bound to Ub-mitochondria  (Gallus gallus)


name: LC3 binds the autophagosome membrane Atg5-Atg12 complex (Gallus gallus)


name: p62 links damaged mitochondria to LC3 (Gallus gallus)


name: p62 binds ubiquitinated mitochondrial substrates (Gallus gallus)


name: PINK1-PRKN Mediated Mitophagy (Drosophila melanogaster)


name: PINK1 phosphorylates PRKN at S65 (Drosophila melanogaster)


name: OPTN, TBK1 bind ubiquitinated MOM proteins (Drosophila melanogaster)


name: Pink1 is cleaved on healthy mitochondria (Drosophila melanogaster)


name: PINK1 is autophosphorylated (Drosophila melanogaster)


name: TBK1 is phosphorylated within TBK1:OPTN:Ub-mitochondrial proteins (Drosophila melanogaster)


name: PINK1 phosphorylates Ub on MOM proteins (Drosophila melanogaster)


name: Uncleaved Pink1 accumulates in damaged mitochondria (Drosophila melanogaster)


name: OPTN binds ATG9A (Drosophila melanogaster)


name: PRKN binds p-S-Ub:MOM proteins (Drosophila melanogaster)


name: p-S-TBK1 phosphorylates OPTN (Drosophila melanogaster)


name: p62 binds ubiquitinated mitochondrial substrates (Drosophila melanogaster)


name: PRKN ubiquitinates MOM substrates (Drosophila melanogaster)


name: PINK1-PRKN Mediated Mitophagy (Caenorhabditis elegans)


name: LC3 binds the autophagosome membrane Atg5-Atg12 complex (Caenorhabditis elegans)


name: PINK1 is autophosphorylated (Caenorhabditis elegans)


name: Uncleaved Pink1 accumulates in damaged mitochondria (Caenorhabditis elegans)


name: p62 binds ubiquitinated mitochondrial substrates (Caenorhabditis elegans)


name: p62 links damaged mitochondria to LC3 (Caenorhabditis elegans)


name: PINK1 phosphorylates Ub on MOM proteins (Caenorhabditis elegans)


name: Pink1 is cleaved on healthy mitochondria (Caenorhabditis elegans)


name: PINK1-PRKN Mediated Mitophagy (Dictyostelium discoideum)


name: LC3 binds the autophagosome membrane Atg5-Atg12 complex (Dictyostelium discoideum)


name: p62 links damaged mitochondria to LC3 (Dictyostelium discoideum)


name: p62 binds ubiquitinated mitochondrial substrates (Dictyostelium discoideum)


name: PINK1-PRKN Mediated Mitophagy (Schizosaccharomyces pombe)


name: PRKN binds p-S-Ub:MOM proteins (Schizosaccharomyces pombe)


name: PRKN ubiquitinates MOM substrates (Schizosaccharomyces pombe)


name: PINK1-PRKN Mediated Mitophagy (Saccharomyces cerevisiae)


name: PRKN ubiquitinates MOM substrates (Saccharomyces cerevisiae)


name: PRKN binds p-S-Ub:MOM proteins (Saccharomyces cerevisiae)


name: PINK1-PRKN Mediated Mitophagy (Plasmodium falciparum)


name: PRKN binds p-S-Ub:MOM proteins (Plasmodium falciparum)


name: PRKN ubiquitinates MOM substrates (Plasmodium falciparum)


name: Receptor Mediated Mitophagy (Homo sapiens)


name: FUNDC1 is phosphorylated by CK2 (Homo sapiens)


name: Phosphorylated FUNDC1 links damaged mitochondria to LC3 (Homo sapiens)


name: LC3 binds the autophagosome membrane Atg5-Atg12 complex (Homo sapiens)


name: FUNDC1 is phosphorylated by ULK1 at Ser17 (Homo sapiens)


name: p-S13, FUNDC1 is phosphorylated by CK2 at Tyr18 (Homo sapiens)


name: p-S13-FUNDC1 is dephosphorylated by PGAM5 (Homo sapiens)


name: ULK1 Translocates to the mitochondria (Homo sapiens)


name: Receptor Mediated Mitophagy (Mus musculus)


name: ULK1 Translocates to the mitochondria (Mus musculus)


name: p-S13, FUNDC1 is phosphorylated by CK2 at Tyr18 (Mus musculus)


name: Phosphorylated FUNDC1 links damaged mitochondria to LC3 (Mus musculus)


name: LC3 binds the autophagosome membrane Atg5-Atg12 complex (Mus musculus)


name: p-S13-FUNDC1 is dephosphorylated by PGAM5 (Mus musculus)


name: FUNDC1 is phosphorylated by CK2 (Mus musculus)


name: FUNDC1 is phosphorylated by ULK1 at Ser17 (Mus musculus)


name: Receptor Mediated Mitophagy (Rattus norvegicus)


name: ULK1 Translocates to the mitochondria (Rattus norvegicus)


name: Phosphorylated FUNDC1 links damaged mitochondria to LC3 (Rattus norvegicus)


name: FUNDC1 is phosphorylated by CK2 (Rattus norvegicus)


name: p-S13, FUNDC1 is phosphorylated by CK2 at Tyr18 (Rattus norvegicus)


name: p-S13-FUNDC1 is dephosphorylated by PGAM5 (Rattus norvegicus)


name: LC3 binds the autophagosome membrane Atg5-Atg12 complex (Rattus norvegicus)


name: FUNDC1 is phosphorylated by ULK1 at Ser17 (Rattus norvegicus)


name: Receptor Mediated Mitophagy (Canis familiaris)


name: p-S13-FUNDC1 is dephosphorylated by PGAM5 (Canis familiaris)


name: LC3 binds the autophagosome membrane Atg5-Atg12 complex (Canis familiaris)


name: ULK1 Translocates to the mitochondria (Canis familiaris)


name: p-S13, FUNDC1 is phosphorylated by CK2 at Tyr18 (Canis familiaris)


name: FUNDC1 is phosphorylated by CK2 (Canis familiaris)


name: FUNDC1 is phosphorylated by ULK1 at Ser17 (Canis familiaris)


name: Phosphorylated FUNDC1 links damaged mitochondria to LC3 (Canis familiaris)


name: Receptor Mediated Mitophagy (Bos taurus)


name: FUNDC1 is phosphorylated by CK2 (Bos taurus)


name: p-S13, FUNDC1 is phosphorylated by CK2 at Tyr18 (Bos taurus)


name: FUNDC1 is phosphorylated by ULK1 at Ser17 (Bos taurus)


name: ULK1 Translocates to the mitochondria (Bos taurus)


name: p-S13-FUNDC1 is dephosphorylated by PGAM5 (Bos taurus)


name: Phosphorylated FUNDC1 links damaged mitochondria to LC3 (Bos taurus)


name: LC3 binds the autophagosome membrane Atg5-Atg12 complex (Bos taurus)


name: Receptor Mediated Mitophagy (Sus scrofa)


name: LC3 binds the autophagosome membrane Atg5-Atg12 complex (Sus scrofa)


name: p-S13-FUNDC1 is dephosphorylated by PGAM5 (Sus scrofa)


name: Phosphorylated FUNDC1 links damaged mitochondria to LC3 (Sus scrofa)


name: p-S13, FUNDC1 is phosphorylated by CK2 at Tyr18 (Sus scrofa)


name: ULK1 Translocates to the mitochondria (Sus scrofa)


name: FUNDC1 is phosphorylated by ULK1 at Ser17 (Sus scrofa)


name: FUNDC1 is phosphorylated by CK2 (Sus scrofa)


name: Receptor Mediated Mitophagy (Danio rerio)


name: Phosphorylated FUNDC1 links damaged mitochondria to LC3 (Danio rerio)


name: LC3 binds the autophagosome membrane Atg5-Atg12 complex (Danio rerio)


name: p-S13, FUNDC1 is phosphorylated by CK2 at Tyr18 (Danio rerio)


name: p-S13-FUNDC1 is dephosphorylated by PGAM5 (Danio rerio)


name: Receptor Mediated Mitophagy (Xenopus tropicalis)


name: ULK1 Translocates to the mitochondria (Xenopus tropicalis)


name: FUNDC1 is phosphorylated by ULK1 at Ser17 (Xenopus tropicalis)


name: Phosphorylated FUNDC1 links damaged mitochondria to LC3 (Xenopus tropicalis)


name: LC3 binds the autophagosome membrane Atg5-Atg12 complex (Xenopus tropicalis)


name: p-S13-FUNDC1 is dephosphorylated by PGAM5 (Xenopus tropicalis)


name: Receptor Mediated Mitophagy (Gallus gallus)


name: p-S13-FUNDC1 is dephosphorylated by PGAM5 (Gallus gallus)


name: FUNDC1 is phosphorylated by ULK1 at Ser17 (Gallus gallus)


name: ULK1 Translocates to the mitochondria (Gallus gallus)


name: LC3 binds the autophagosome membrane Atg5-Atg12 complex (Gallus gallus)


name: Phosphorylated FUNDC1 links damaged mitochondria to LC3 (Gallus gallus)


name: p-S13, FUNDC1 is phosphorylated by CK2 at Tyr18 (Gallus gallus)


name: Receptor Mediated Mitophagy (Drosophila melanogaster)


name: FUNDC1 is phosphorylated by ULK1 at Ser17 (Drosophila melanogaster)


name: FUNDC1 is phosphorylated by CK2 (Drosophila melanogaster)


name: p-S13-FUNDC1 is dephosphorylated by PGAM5 (Drosophila melanogaster)


name: p-S13, FUNDC1 is phosphorylated by CK2 at Tyr18 (Drosophila melanogaster)


name: ULK1 Translocates to the mitochondria (Drosophila melanogaster)


name: Receptor Mediated Mitophagy (Caenorhabditis elegans)


name: p-S13-FUNDC1 is dephosphorylated by PGAM5 (Caenorhabditis elegans)


name: Phosphorylated FUNDC1 links damaged mitochondria to LC3 (Caenorhabditis elegans)


name: p-S13, FUNDC1 is phosphorylated by CK2 at Tyr18 (Caenorhabditis elegans)


name: ULK1 Translocates to the mitochondria (Caenorhabditis elegans)


name: LC3 binds the autophagosome membrane Atg5-Atg12 complex (Caenorhabditis elegans)


name: FUNDC1 is phosphorylated by ULK1 at Ser17 (Caenorhabditis elegans)


name: FUNDC1 is phosphorylated by CK2 (Caenorhabditis elegans)


name: Receptor Mediated Mitophagy (Dictyostelium discoideum)


name: LC3 binds the autophagosome membrane Atg5-Atg12 complex (Dictyostelium discoideum)


name: Phosphorylated FUNDC1 links damaged mitochondria to LC3 (Dictyostelium discoideum)


name: FUNDC1 is phosphorylated by ULK1 at Ser17 (Dictyostelium discoideum)


name: FUNDC1 is phosphorylated by CK2 (Dictyostelium discoideum)


name: ULK1 Translocates to the mitochondria (Dictyostelium discoideum)


name: Receptor Mediated Mitophagy (Schizosaccharomyces pombe)


name: Phosphorylated FUNDC1 links damaged mitochondria to LC3 (Schizosaccharomyces pombe)


name: FUNDC1 is phosphorylated by ULK1 at Ser17 (Schizosaccharomyces pombe)


name: FUNDC1 is phosphorylated by CK2 (Schizosaccharomyces pombe)


name: ULK1 Translocates to the mitochondria (Schizosaccharomyces pombe)


name: LC3 binds the autophagosome membrane Atg5-Atg12 complex (Schizosaccharomyces pombe)


name: Receptor Mediated Mitophagy (Saccharomyces cerevisiae)


name: LC3 binds the autophagosome membrane Atg5-Atg12 complex (Saccharomyces cerevisiae)


name: Phosphorylated FUNDC1 links damaged mitochondria to LC3 (Saccharomyces cerevisiae)


name: FUNDC1 is phosphorylated by ULK1 at Ser17 (Saccharomyces cerevisiae)


name: FUNDC1 is phosphorylated by CK2 (Saccharomyces cerevisiae)


name: ULK1 Translocates to the mitochondria (Saccharomyces cerevisiae)


lipophagy

description: The selective degradation of lipid droplets by macroautophagy.


name: PRKAA2 dissociate from p-PLINs:HSPA8 (Homo sapiens)


name: PLINs:HSPA8 binds PRKAA2 (Homo sapiens)


name: PRKAA2 phosphorylates PLINs (Homo sapiens)


name: p-PLINs translocate from lipid droplet surface to cytosol (Homo sapiens)


pexophagy

description: The selective autophagy process in which a peroxisome is degraded by macroautophagy.


deubiquitinase activity

description: An isopeptidase activity that cleaves ubiquitin from a target protein to which it is conjugated.


name: ATM:PEX5 binds ATM (Homo sapiens)


name: NBR1 translocates from cytosol to perixosomal membrane (Homo sapiens)


name: SQSTM1 binds ATM dimer:Ub-p-PEX5 (Homo sapiens)


name: ATM dimer:PEX5 phosphorylates PEX5 (Homo sapiens)


name: ATM dimer:p-PEX5 ubiquitinates to form ATM dimer:Ub-p-PEX5 (Homo sapiens)


name: MAP1LC3B binds ATM dimer:Ub-p-PEX5:SQSTM1 (Homo sapiens)


name: MAP1LC3B binds ATM dimer:Ub-p-PEX5:SQSTM1:NBR1 (Homo sapiens)


name: NBR1 binds ATM:Ub-p-PEX5:SQSTM1 (Homo sapiens)


name: USP30 binds ATM dimer:Ub-p-PEX5 (Homo sapiens)


name: ATM:PEX5 translocates from cytosol to peroxisomal membrane (Homo sapiens)


name: ATM dimer:p-PEX5 ubiquitinates to form ATM dimer:Ub-p-PEX5 (Mus musculus)


name: MAP1LC3B binds ATM dimer:Ub-p-PEX5:SQSTM1 (Mus musculus)


name: USP30 binds ATM dimer:Ub-p-PEX5 (Mus musculus)


name: ATM:PEX5 translocates from cytosol to peroxisomal membrane (Mus musculus)


name: NBR1 binds ATM:Ub-p-PEX5:SQSTM1 (Mus musculus)


name: USP30 deubiquitinates ATM dimer:Ub-p-PEX5 (Mus musculus)


name: ATM dimer:PEX5 phosphorylates PEX5 (Mus musculus)


name: MAP1LC3B binds ATM dimer:Ub-p-PEX5:SQSTM1:NBR1 (Mus musculus)


name: ATM:PEX5 binds ATM (Mus musculus)


name: SQSTM1 binds ATM dimer:Ub-p-PEX5 (Mus musculus)


name: ATM:PEX5 binds ATM (Rattus norvegicus)


name: ATM dimer:p-PEX5 ubiquitinates to form ATM dimer:Ub-p-PEX5 (Rattus norvegicus)


name: SQSTM1 binds ATM dimer:Ub-p-PEX5 (Rattus norvegicus)


name: NBR1 binds ATM:Ub-p-PEX5:SQSTM1 (Rattus norvegicus)


name: USP30 deubiquitinates ATM dimer:Ub-p-PEX5 (Rattus norvegicus)


name: MAP1LC3B binds ATM dimer:Ub-p-PEX5:SQSTM1 (Rattus norvegicus)


name: USP30 binds ATM dimer:Ub-p-PEX5 (Rattus norvegicus)


name: ATM:PEX5 translocates from cytosol to peroxisomal membrane (Rattus norvegicus)


name: MAP1LC3B binds ATM dimer:Ub-p-PEX5:SQSTM1:NBR1 (Rattus norvegicus)


name: ATM dimer:PEX5 phosphorylates PEX5 (Rattus norvegicus)


name: MAP1LC3B binds ATM dimer:Ub-p-PEX5:SQSTM1:NBR1 (Canis familiaris)


name: ATM dimer:PEX5 phosphorylates PEX5 (Canis familiaris)


name: USP30 binds ATM dimer:Ub-p-PEX5 (Canis familiaris)


name: MAP1LC3B binds ATM dimer:Ub-p-PEX5:SQSTM1 (Canis familiaris)


name: ATM:PEX5 translocates from cytosol to peroxisomal membrane (Canis familiaris)


name: NBR1 binds ATM:Ub-p-PEX5:SQSTM1 (Canis familiaris)


name: SQSTM1 binds ATM dimer:Ub-p-PEX5 (Canis familiaris)


name: ATM dimer:p-PEX5 ubiquitinates to form ATM dimer:Ub-p-PEX5 (Canis familiaris)


name: USP30 deubiquitinates ATM dimer:Ub-p-PEX5 (Canis familiaris)


name: ATM:PEX5 binds ATM (Canis familiaris)


name: MAP1LC3B binds ATM dimer:Ub-p-PEX5:SQSTM1:NBR1 (Bos taurus)


name: ATM dimer:PEX5 phosphorylates PEX5 (Bos taurus)


name: NBR1 binds ATM:Ub-p-PEX5:SQSTM1 (Bos taurus)


name: MAP1LC3B binds ATM dimer:Ub-p-PEX5:SQSTM1 (Bos taurus)


name: ATM:PEX5 translocates from cytosol to peroxisomal membrane (Bos taurus)


name: USP30 deubiquitinates ATM dimer:Ub-p-PEX5 (Bos taurus)


name: ATM dimer:p-PEX5 ubiquitinates to form ATM dimer:Ub-p-PEX5 (Bos taurus)


name: USP30 binds ATM dimer:Ub-p-PEX5 (Bos taurus)


name: SQSTM1 binds ATM dimer:Ub-p-PEX5 (Bos taurus)


name: ATM:PEX5 binds ATM (Bos taurus)


name: MAP1LC3B binds ATM dimer:Ub-p-PEX5:SQSTM1:NBR1 (Sus scrofa)


name: ATM dimer:PEX5 phosphorylates PEX5 (Sus scrofa)


name: USP30 deubiquitinates ATM dimer:Ub-p-PEX5 (Sus scrofa)


name: NBR1 binds ATM:Ub-p-PEX5:SQSTM1 (Sus scrofa)


name: USP30 binds ATM dimer:Ub-p-PEX5 (Sus scrofa)


name: MAP1LC3B binds ATM dimer:Ub-p-PEX5:SQSTM1 (Sus scrofa)


name: ATM:PEX5 translocates from cytosol to peroxisomal membrane (Sus scrofa)


name: ATM dimer:p-PEX5 ubiquitinates to form ATM dimer:Ub-p-PEX5 (Sus scrofa)


name: SQSTM1 binds ATM dimer:Ub-p-PEX5 (Sus scrofa)


name: ATM:PEX5 binds ATM (Sus scrofa)


name: MAP1LC3B binds ATM dimer:Ub-p-PEX5:SQSTM1:NBR1 (Gallus gallus)


name: ATM dimer:PEX5 phosphorylates PEX5 (Gallus gallus)


name: ATM:PEX5 binds ATM (Gallus gallus)


name: USP30 deubiquitinates ATM dimer:Ub-p-PEX5 (Gallus gallus)


name: ATM dimer:p-PEX5 ubiquitinates to form ATM dimer:Ub-p-PEX5 (Gallus gallus)


name: SQSTM1 binds ATM dimer:Ub-p-PEX5 (Gallus gallus)


name: USP30 binds ATM dimer:Ub-p-PEX5 (Gallus gallus)


name: NBR1 binds ATM:Ub-p-PEX5:SQSTM1 (Gallus gallus)


name: MAP1LC3B binds ATM dimer:Ub-p-PEX5:SQSTM1 (Gallus gallus)


name: ATM:PEX5 translocates from cytosol to peroxisomal membrane (Gallus gallus)


name: ATM:PEX5 translocates from cytosol to peroxisomal membrane (Drosophila melanogaster)


name: ATM:PEX5 binds ATM (Drosophila melanogaster)


name: USP30 binds ATM dimer:Ub-p-PEX5 (Drosophila melanogaster)


name: USP30 deubiquitinates ATM dimer:Ub-p-PEX5 (Drosophila melanogaster)


name: ATM dimer:p-PEX5 ubiquitinates to form ATM dimer:Ub-p-PEX5 (Drosophila melanogaster)


name: SQSTM1 binds ATM dimer:Ub-p-PEX5 (Drosophila melanogaster)


name: ATM binds PEX5 (Drosophila melanogaster)


name: ATM dimer:PEX5 phosphorylates PEX5 (Drosophila melanogaster)


name: ATM:PEX5 binds ATM (Dictyostelium discoideum)


name: ATM dimer:PEX5 phosphorylates PEX5 (Dictyostelium discoideum)


name: MAP1LC3B binds ATM dimer:Ub-p-PEX5:SQSTM1:NBR1 (Dictyostelium discoideum)


name: MAP1LC3B binds ATM dimer:Ub-p-PEX5:SQSTM1 (Dictyostelium discoideum)


name: ATM binds PEX5 (Dictyostelium discoideum)


name: NBR1 binds ATM:Ub-p-PEX5:SQSTM1 (Dictyostelium discoideum)


name: ATM:PEX5 translocates from cytosol to peroxisomal membrane (Dictyostelium discoideum)


name: ATM dimer:p-PEX5 ubiquitinates to form ATM dimer:Ub-p-PEX5 (Dictyostelium discoideum)


name: NBR1 binds MAP1LC3B (Dictyostelium discoideum)


name: SQSTM1 binds ATM dimer:Ub-p-PEX5 (Dictyostelium discoideum)


name: ATM dimer:PEX5 phosphorylates PEX5 (Schizosaccharomyces pombe)


name: ATM binds PEX5 (Schizosaccharomyces pombe)


name: ATM:PEX5 binds ATM (Schizosaccharomyces pombe)


name: USP30 deubiquitinates ATM dimer:Ub-p-PEX5 (Schizosaccharomyces pombe)


name: ATM:PEX5 translocates from cytosol to peroxisomal membrane (Schizosaccharomyces pombe)


name: USP30 binds ATM dimer:Ub-p-PEX5 (Schizosaccharomyces pombe)


name: ATM dimer:p-PEX5 ubiquitinates to form ATM dimer:Ub-p-PEX5 (Schizosaccharomyces pombe)


name: ATM:PEX5 translocates from cytosol to peroxisomal membrane (Saccharomyces cerevisiae)


name: ATM dimer:p-PEX5 ubiquitinates to form ATM dimer:Ub-p-PEX5 (Saccharomyces cerevisiae)


name: ATM dimer:PEX5 phosphorylates PEX5 (Saccharomyces cerevisiae)


name: ATM binds PEX5 (Saccharomyces cerevisiae)


name: ATM:PEX5 binds ATM (Saccharomyces cerevisiae)


aggrephagy

description: The selective degradation of protein aggregates by macroautophagy.


name: PolyUb-Misfolded Proteins:HDAC6 bind dynein motor (Homo sapiens)


name: Dynein motors transport misfolded proteins (Homo sapiens)


name: Misfolded proteins bind PRKN:UBE2N:UBE2V1:Ub (Homo sapiens)


name: PolyUb-misfolded proteins bind VCP:HDAC6:HSP90:HSF1 (Homo sapiens)


name: Ub:misfolded proteins polymerize to PolyUb:misfolded proteins (Homo sapiens)


name: E2 enzyme UBE2N:UBE2V1 binds ubiquitin (Homo sapiens)


name: Parkin binds Ub:UBE2N:UBE2V1 (Homo sapiens)


name: Aggresome dissociates from dynein and microtubule (Homo sapiens)


name: PolyUb:misfolded proteins dissociate from PRKN:UBE2N:UBE2V1 (Homo sapiens)


name: Misfolded proteins:HDAC6:Dynein motor binds microtubule (Homo sapiens)


name: PolyUb-Misfolded proteins bind vimentin to form aggresome (Homo sapiens)


name: Parkin transfers Ub to misfolded proteins (Homo sapiens)


name: PolyUb-Misfolded Proteins:HDAC6 dissociate from complex (Homo sapiens)


name: Misfolded proteins translocate from cilium to cytosol (Homo sapiens)


name: ROS positively regulates misfolding of cilia proteins (Homo sapiens)


name: Aggresome dissociates from dynein and microtubule (Mus musculus)


name: Ub:misfolded proteins polymerize to PolyUb:misfolded proteins (Mus musculus)


name: Parkin binds Ub:UBE2N:UBE2V1 (Mus musculus)


name: Parkin transfers Ub to misfolded proteins (Mus musculus)


name: Misfolded proteins bind PRKN:UBE2N:UBE2V1:Ub (Mus musculus)


name: PolyUb-Misfolded Proteins:HDAC6 bind dynein motor (Mus musculus)


name: PolyUb-Misfolded proteins bind vimentin to form aggresome (Mus musculus)


name: PolyUb:misfolded proteins dissociate from PRKN:UBE2N:UBE2V1 (Mus musculus)


name: Aggresome dissociates from dynein and microtubule (Rattus norvegicus)


name: Parkin transfers Ub to misfolded proteins (Rattus norvegicus)


name: PolyUb-Misfolded Proteins:HDAC6 bind dynein motor (Rattus norvegicus)


name: Ub:misfolded proteins polymerize to PolyUb:misfolded proteins (Rattus norvegicus)


name: Misfolded proteins bind PRKN:UBE2N:UBE2V1:Ub (Rattus norvegicus)


name: PolyUb-Misfolded proteins bind vimentin to form aggresome (Rattus norvegicus)


name: Aggresome dissociates from dynein and microtubule (Canis familiaris)


name: Ub:misfolded proteins polymerize to PolyUb:misfolded proteins (Canis familiaris)


name: PolyUb-Misfolded proteins bind vimentin to form aggresome (Canis familiaris)


name: PolyUb:misfolded proteins dissociate from PRKN:UBE2N:UBE2V1 (Canis familiaris)


name: Parkin transfers Ub to misfolded proteins (Canis familiaris)


name: Misfolded proteins bind PRKN:UBE2N:UBE2V1:Ub (Canis familiaris)


name: PolyUb-Misfolded Proteins:HDAC6 bind dynein motor (Canis familiaris)


name: Parkin binds Ub:UBE2N:UBE2V1 (Canis familiaris)


name: Ub:misfolded proteins polymerize to PolyUb:misfolded proteins (Bos taurus)


name: Misfolded proteins bind PRKN:UBE2N:UBE2V1:Ub (Bos taurus)


name: Aggresome dissociates from dynein and microtubule (Bos taurus)


name: Parkin transfers Ub to misfolded proteins (Bos taurus)


name: PolyUb-Misfolded proteins bind vimentin to form aggresome (Bos taurus)


name: PolyUb-Misfolded Proteins:HDAC6 bind dynein motor (Bos taurus)


name: Misfolded proteins bind PRKN:UBE2N:UBE2V1:Ub (Sus scrofa)


name: PolyUb-Misfolded proteins bind vimentin to form aggresome (Sus scrofa)


name: PolyUb-Misfolded Proteins:HDAC6 bind dynein motor (Sus scrofa)


name: Parkin transfers Ub to misfolded proteins (Sus scrofa)


name: Ub:misfolded proteins polymerize to PolyUb:misfolded proteins (Sus scrofa)


name: Aggresome dissociates from dynein and microtubule (Sus scrofa)


name: Parkin binds Ub:UBE2N:UBE2V1 (Danio rerio)


name: PolyUb-Misfolded Proteins:HDAC6 bind dynein motor (Danio rerio)


name: Misfolded proteins bind PRKN:UBE2N:UBE2V1:Ub (Danio rerio)


name: PolyUb-Misfolded proteins bind vimentin to form aggresome (Danio rerio)


name: PolyUb:misfolded proteins dissociate from PRKN:UBE2N:UBE2V1 (Danio rerio)


name: Ub:misfolded proteins polymerize to PolyUb:misfolded proteins (Danio rerio)


name: Parkin transfers Ub to misfolded proteins (Danio rerio)


name: PolyUb-Misfolded proteins bind vimentin to form aggresome (Xenopus tropicalis)


name: Aggresome dissociates from dynein and microtubule (Xenopus tropicalis)


name: Parkin transfers Ub to misfolded proteins (Gallus gallus)


name: Ub:misfolded proteins polymerize to PolyUb:misfolded proteins (Gallus gallus)


name: Misfolded proteins bind PRKN:UBE2N:UBE2V1:Ub (Gallus gallus)


name: PolyUb-Misfolded proteins bind vimentin to form aggresome (Gallus gallus)


name: Parkin transfers Ub to misfolded proteins (Drosophila melanogaster)


name: PolyUb-Misfolded Proteins:HDAC6 bind dynein motor (Drosophila melanogaster)


name: PolyUb:misfolded proteins dissociate from PRKN:UBE2N:UBE2V1 (Drosophila melanogaster)


name: Ub:misfolded proteins polymerize to PolyUb:misfolded proteins (Drosophila melanogaster)


name: Misfolded proteins bind PRKN:UBE2N:UBE2V1:Ub (Drosophila melanogaster)


name: Parkin binds Ub:UBE2N:UBE2V1 (Drosophila melanogaster)


name: PolyUb-Misfolded Proteins:HDAC6 bind dynein motor (Caenorhabditis elegans)


name: Ub:misfolded proteins polymerize to PolyUb:misfolded proteins (Caenorhabditis elegans)


name: Misfolded proteins bind PRKN:UBE2N:UBE2V1:Ub (Caenorhabditis elegans)


name: Parkin transfers Ub to misfolded proteins (Caenorhabditis elegans)


name: Misfolded proteins bind PRKN:UBE2N:UBE2V1:Ub (Dictyostelium discoideum)


name: Parkin transfers Ub to misfolded proteins (Dictyostelium discoideum)


name: Parkin binds Ub:UBE2N:UBE2V1 (Dictyostelium discoideum)


name: PolyUb:misfolded proteins dissociate from PRKN:UBE2N:UBE2V1 (Dictyostelium discoideum)


name: Ub:misfolded proteins polymerize to PolyUb:misfolded proteins (Dictyostelium discoideum)


name: PolyUb-Misfolded Proteins:HDAC6 bind dynein motor (Dictyostelium discoideum)


name: Aggresome dissociates from dynein and microtubule (Dictyostelium discoideum)


name: Parkin transfers Ub to misfolded proteins (Schizosaccharomyces pombe)


name: Misfolded proteins bind PRKN:UBE2N:UBE2V1:Ub (Schizosaccharomyces pombe)


name: Ub:misfolded proteins polymerize to PolyUb:misfolded proteins (Schizosaccharomyces pombe)


name: PolyUb:misfolded proteins dissociate from PRKN:UBE2N:UBE2V1 (Schizosaccharomyces pombe)


name: Parkin binds Ub:UBE2N:UBE2V1 (Schizosaccharomyces pombe)


name: Parkin transfers Ub to misfolded proteins (Saccharomyces cerevisiae)


name: Parkin binds Ub:UBE2N:UBE2V1 (Saccharomyces cerevisiae)


name: Ub:misfolded proteins polymerize to PolyUb:misfolded proteins (Saccharomyces cerevisiae)


name: Misfolded proteins bind PRKN:UBE2N:UBE2V1:Ub (Plasmodium falciparum)


name: Aggresome dissociates from dynein and microtubule (Plasmodium falciparum)


name: PolyUb-Misfolded Proteins:HDAC6 bind dynein motor (Plasmodium falciparum)


name: PolyUb:misfolded proteins dissociate from PRKN:UBE2N:UBE2V1 (Plasmodium falciparum)


name: Parkin transfers Ub to misfolded proteins (Plasmodium falciparum)


name: Ub:misfolded proteins polymerize to PolyUb:misfolded proteins (Plasmodium falciparum)


name: Parkin binds Ub:UBE2N:UBE2V1 (Plasmodium falciparum)


name: MTORC1 dissociates from ULK complex (Mus musculus)


name: Beclin-1 complex translocates to the ER (Mus musculus)


name: ULK1 phosphorylates AMBRA1:BECN1 complex (Mus musculus)


name: AMPK (complex) phosphorylates ULK1 (complex) (Mus musculus)


name: Active MTORC1 binds the ULK1 complex (Mus musculus)


name: AMBRA1 binds DYNLL1,DYNLL2 (Mus musculus)


name: LC3 de-lipidation by ATG4 (Mus musculus)


name: ULK1 phosphorylates ATG13 and RB1CC1 (Mus musculus)


name: ATG12 forms a thioester bond with ATG7 dimer (Mus musculus)


name: AMBRA1:DYNLL1,DYNLL2 binds BECN1 complex (Mus musculus)


name: Thr-180 of ULK1 is phosphorylated (Mus musculus)


name: ATG16L1 complex transfers LC3 from ATG3 to PE (Mus musculus)


name: ATG10 dissociates from ATG12:ATG5 (Mus musculus)


name: ATG3 transfers LC3 from ATG7 to ATG3 (Mus musculus)


name: The phagophore extends from the PIP3-enriched structure (Mus musculus)


name: BECN1 complex, p-AMBRA1 dissociate from DYNLL1,DYNLL2 (Mus musculus)


name: p-AMPK:AMP binds the ULK complex (Mus musculus)


name: Active MTORC1 phosphorylates ULK1 (Mus musculus)


name: Beclin-1 complex phosphorylates PtdIns (Mus musculus)


name: ULK1 phosphorylates Beclin-1 (Mus musculus)


name: WIPI2 binds ATG12:ATG5:ATG16L (Mus musculus)


name: LC3:ATG7 dimer binds ATG3 (Mus musculus)


name: ULK complex translocates to the ER (Mus musculus)


name: Rheb in the MTORC1 complex hydrolyses GTP (Mus musculus)


name: ATG7:ATG3:LC3 dissociates (Mus musculus)


name: ATG12:ATG7:CysO572-ATG7 binds ATG10 (Mus musculus)


name: MTMR14, MTMR3 dephosphorylate PI3P (Mus musculus)


name: p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex (Mus musculus)


name: ATG10 transfers ATG12 from ATG10 to ATG5 (Mus musculus)


name: LC3 is cleaved by ATG4 (Rattus norvegicus)


name: ATG12 binds ATG7 dimer (Rattus norvegicus)


name: Beclin-1 complex phosphorylates PtdIns (Rattus norvegicus)


name: Autophagosome maturation (Rattus norvegicus)


name: AMBRA1:DYNLL1,DYNLL2 binds BECN1 complex (Rattus norvegicus)


name: BECN1 complex, p-AMBRA1 dissociate from DYNLL1,DYNLL2 (Rattus norvegicus)


name: ATG12:ATG7:CysO572-ATG7 binds ATG10 (Rattus norvegicus)


name: ATG10 transfers ATG12 from ATG10 to ATG5 (Rattus norvegicus)


name: Rheb in the MTORC1 complex hydrolyses GTP (Rattus norvegicus)


name: LC3:ATG7 dimer binds ATG3 (Rattus norvegicus)


name: ATG7:ATG3:LC3 dissociates (Rattus norvegicus)


name: p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex (Rattus norvegicus)


name: LC3 binds ATG7 dimer (Rattus norvegicus)


name: LC3 de-lipidation by ATG4 (Rattus norvegicus)


name: ATG10:ATG12 binds ATG5 (Rattus norvegicus)


name: Active MTORC1 binds the ULK1 complex (Rattus norvegicus)


name: ATG12 forms a thioester bond with ATG7 dimer (Rattus norvegicus)


name: MTORC1 dissociates from ULK complex (Rattus norvegicus)


name: ATG3 transfers LC3 from ATG7 to ATG3 (Rattus norvegicus)


name: ATG16L1 complex transfers LC3 from ATG3 to PE (Rattus norvegicus)


name: The phagophore extends from the PIP3-enriched structure (Rattus norvegicus)


name: Thr-180 of ULK1 is phosphorylated (Rattus norvegicus)


name: ATG10 dissociates from ATG12:ATG5 (Rattus norvegicus)


name: ULK1 phosphorylates AMBRA1:BECN1 complex (Rattus norvegicus)


name: Active MTORC1 phosphorylates ULK1 (Rattus norvegicus)


name: p-AMPK:AMP binds the ULK complex (Rattus norvegicus)


name: ULK1 phosphorylates ATG13 and RB1CC1 (Rattus norvegicus)


name: ULK1 phosphorylates Beclin-1 (Rattus norvegicus)


name: AMPK (complex) phosphorylates ULK1 (complex) (Rattus norvegicus)


name: ULK1 is dephosphorylated (Rattus norvegicus)


name: WIPI2 binds ATG12:ATG5:ATG16L (Rattus norvegicus)


name: Beclin-1 complex translocates to the ER (Rattus norvegicus)


name: MTMR14, MTMR3 dephosphorylate PI3P (Rattus norvegicus)


name: ULK complex translocates to the ER (Rattus norvegicus)


name: AMBRA1 binds DYNLL1,DYNLL2 (Rattus norvegicus)


name: AMPK (complex) phosphorylates ULK1 (complex) (Canis familiaris)


name: LC3 de-lipidation by ATG4 (Canis familiaris)


name: AMBRA1:DYNLL1,DYNLL2 binds BECN1 complex (Canis familiaris)


name: BECN1 complex, p-AMBRA1 dissociate from DYNLL1,DYNLL2 (Canis familiaris)


name: Thr-180 of ULK1 is phosphorylated (Canis familiaris)


name: ULK1 phosphorylates AMBRA1:BECN1 complex (Canis familiaris)


name: ATG16L1 complex transfers LC3 from ATG3 to PE (Canis familiaris)


name: Active MTORC1 phosphorylates ULK1 (Canis familiaris)


name: p-AMPK:AMP binds the ULK complex (Canis familiaris)


name: ATG10 dissociates from ATG12:ATG5 (Canis familiaris)


name: ATG3 transfers LC3 from ATG7 to ATG3 (Canis familiaris)


name: The phagophore extends from the PIP3-enriched structure (Canis familiaris)


name: AMBRA1 binds DYNLL1,DYNLL2 (Canis familiaris)


name: ULK1 is dephosphorylated (Canis familiaris)


name: ULK1 phosphorylates Beclin-1 (Canis familiaris)


name: ATG10 transfers ATG12 from ATG10 to ATG5 (Canis familiaris)


name: ATG12:ATG7:CysO572-ATG7 binds ATG10 (Canis familiaris)


name: p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex (Canis familiaris)


name: Beclin-1 complex phosphorylates PtdIns (Canis familiaris)


name: ATG12 forms a thioester bond with ATG7 dimer (Canis familiaris)


name: ULK complex translocates to the ER (Canis familiaris)


name: WIPI2 binds ATG12:ATG5:ATG16L (Canis familiaris)


name: Autophagosome maturation (Canis familiaris)


name: ATG7:ATG3:LC3 dissociates (Canis familiaris)


name: Rheb in the MTORC1 complex hydrolyses GTP (Canis familiaris)


name: LC3:ATG7 dimer binds ATG3 (Canis familiaris)


name: MTORC1 dissociates from ULK complex (Canis familiaris)


name: MTMR14, MTMR3 dephosphorylate PI3P (Canis familiaris)


name: ULK1 phosphorylates ATG13 and RB1CC1 (Canis familiaris)


name: ATG12 binds ATG7 dimer (Canis familiaris)


name: Beclin-1 complex translocates to the ER (Canis familiaris)


name: LC3 is cleaved by ATG4 (Canis familiaris)


name: Active MTORC1 binds the ULK1 complex (Canis familiaris)


name: ATG10:ATG12 binds ATG5 (Canis familiaris)


name: AMPK (complex) phosphorylates ULK1 (complex) (Bos taurus)


name: ATG12 forms a thioester bond with ATG7 dimer (Bos taurus)


name: Thr-180 of ULK1 is phosphorylated (Bos taurus)


name: AMBRA1:DYNLL1,DYNLL2 binds BECN1 complex (Bos taurus)


name: BECN1 complex, p-AMBRA1 dissociate from DYNLL1,DYNLL2 (Bos taurus)


name: p-AMPK:AMP binds the ULK complex (Bos taurus)


name: Active MTORC1 phosphorylates ULK1 (Bos taurus)


name: ATG16L1 complex transfers LC3 from ATG3 to PE (Bos taurus)


name: ATG3 transfers LC3 from ATG7 to ATG3 (Bos taurus)


name: ULK1 phosphorylates AMBRA1:BECN1 complex (Bos taurus)


name: The phagophore extends from the PIP3-enriched structure (Bos taurus)


name: Beclin-1 complex phosphorylates PtdIns (Bos taurus)


name: ATG10 dissociates from ATG12:ATG5 (Bos taurus)


name: MTORC1 dissociates from ULK complex (Bos taurus)


name: p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex (Bos taurus)


name: ULK1 phosphorylates Beclin-1 (Bos taurus)


name: Rheb in the MTORC1 complex hydrolyses GTP (Bos taurus)


name: ULK complex translocates to the ER (Bos taurus)


name: MTMR14, MTMR3 dephosphorylate PI3P (Bos taurus)


name: ULK1 phosphorylates ATG13 and RB1CC1 (Bos taurus)


name: Beclin-1 complex translocates to the ER (Bos taurus)


name: WIPI2 binds ATG12:ATG5:ATG16L (Bos taurus)


name: ATG12:ATG7:CysO572-ATG7 binds ATG10 (Bos taurus)


name: ATG10 transfers ATG12 from ATG10 to ATG5 (Bos taurus)


name: Active MTORC1 binds the ULK1 complex (Bos taurus)


name: AMPK (complex) phosphorylates ULK1 (complex) (Sus scrofa)


name: ATG3 transfers LC3 from ATG7 to ATG3 (Sus scrofa)


name: ATG12 forms a thioester bond with ATG7 dimer (Sus scrofa)


name: ATG16L1 complex transfers LC3 from ATG3 to PE (Sus scrofa)


name: Active MTORC1 binds the ULK1 complex (Sus scrofa)


name: The phagophore extends from the PIP3-enriched structure (Sus scrofa)


name: Thr-180 of ULK1 is phosphorylated (Sus scrofa)


name: ATG10 dissociates from ATG12:ATG5 (Sus scrofa)


name: ULK1 phosphorylates Beclin-1 (Sus scrofa)


name: MTORC1 dissociates from ULK complex (Sus scrofa)


name: MTMR14, MTMR3 dephosphorylate PI3P (Sus scrofa)


name: p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex (Sus scrofa)


name: Active MTORC1 phosphorylates ULK1 (Sus scrofa)


name: ULK complex translocates to the ER (Sus scrofa)


name: ULK1 phosphorylates AMBRA1:BECN1 complex (Sus scrofa)


name: p-AMPK:AMP binds the ULK complex (Sus scrofa)


name: WIPI2 binds ATG12:ATG5:ATG16L (Sus scrofa)


name: Beclin-1 complex translocates to the ER (Sus scrofa)


name: ULK1 phosphorylates ATG13 and RB1CC1 (Sus scrofa)


name: ATG10 transfers ATG12 from ATG10 to ATG5 (Sus scrofa)


name: Beclin-1 complex phosphorylates PtdIns (Sus scrofa)


name: ATG12:ATG7:CysO572-ATG7 binds ATG10 (Sus scrofa)


name: Rheb in the MTORC1 complex hydrolyses GTP (Sus scrofa)


name: AMBRA1:DYNLL1,DYNLL2 binds BECN1 complex (Sus scrofa)


name: BECN1 complex, p-AMBRA1 dissociate from DYNLL1,DYNLL2 (Sus scrofa)


name: Active MTORC1 phosphorylates ULK1 (Danio rerio)


name: AMBRA1 binds DYNLL1,DYNLL2 (Danio rerio)


name: p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex (Danio rerio)


name: ATG10 transfers ATG12 from ATG10 to ATG5 (Danio rerio)


name: Rheb in the MTORC1 complex hydrolyses GTP (Danio rerio)


name: ATG10 dissociates from ATG12:ATG5 (Danio rerio)


name: ATG12 binds ATG7 dimer (Xenopus tropicalis)


name: Active MTORC1 binds the ULK1 complex (Xenopus tropicalis)


name: Beclin-1 complex translocates to the ER (Xenopus tropicalis)


name: ULK1 phosphorylates AMBRA1:BECN1 complex (Xenopus tropicalis)


name: ULK complex translocates to the ER (Xenopus tropicalis)


name: Rheb in the MTORC1 complex hydrolyses GTP (Xenopus tropicalis)


name: MTMR14, MTMR3 dephosphorylate PI3P (Xenopus tropicalis)


name: ULK1 phosphorylates Beclin-1 (Xenopus tropicalis)


name: Autophagosome maturation (Xenopus tropicalis)


name: ATG7:ATG3:LC3 dissociates (Xenopus tropicalis)


name: ATG12 forms a thioester bond with ATG7 dimer (Xenopus tropicalis)


name: Beclin-1 complex phosphorylates PtdIns (Xenopus tropicalis)


name: LC3:ATG7 dimer binds ATG3 (Xenopus tropicalis)


name: LC3 binds ATG7 dimer (Xenopus tropicalis)


name: ATG16L1 complex transfers LC3 from ATG3 to PE (Xenopus tropicalis)


name: BECN1 complex, p-AMBRA1 dissociate from DYNLL1,DYNLL2 (Xenopus tropicalis)


name: ULK1 phosphorylates ATG13 and RB1CC1 (Xenopus tropicalis)


name: AMBRA1:DYNLL1,DYNLL2 binds BECN1 complex (Xenopus tropicalis)


name: AMBRA1 binds DYNLL1,DYNLL2 (Xenopus tropicalis)


name: Active MTORC1 phosphorylates ULK1 (Xenopus tropicalis)


name: The phagophore extends from the PIP3-enriched structure (Xenopus tropicalis)


name: ATG3 transfers LC3 from ATG7 to ATG3 (Xenopus tropicalis)


name: MTORC1 dissociates from ULK complex (Xenopus tropicalis)


name: AMPK (complex) phosphorylates ULK1 (complex) (Xenopus tropicalis)


name: Thr-180 of ULK1 is phosphorylated (Xenopus tropicalis)


name: ULK1 is dephosphorylated (Xenopus tropicalis)


name: ATG16L1 complex transfers LC3 from ATG3 to PE (Gallus gallus)


name: ATG3 transfers LC3 from ATG7 to ATG3 (Gallus gallus)


name: The phagophore extends from the PIP3-enriched structure (Gallus gallus)


name: MTORC1 dissociates from ULK complex (Gallus gallus)


name: Thr-180 of ULK1 is phosphorylated (Gallus gallus)


name: LC3 de-lipidation by ATG4 (Gallus gallus)


name: ATG12 forms a thioester bond with ATG7 dimer (Gallus gallus)


name: AMPK (complex) phosphorylates ULK1 (complex) (Gallus gallus)


name: Beclin-1 complex translocates to the ER (Gallus gallus)


name: ULK complex translocates to the ER (Gallus gallus)


name: WIPI2 binds ATG12:ATG5:ATG16L (Gallus gallus)


name: p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex (Gallus gallus)


name: Active MTORC1 binds the ULK1 complex (Gallus gallus)


name: Autophagosome maturation (Gallus gallus)


name: ATG12:ATG7:CysO572-ATG7 binds ATG10 (Gallus gallus)


name: Rheb in the MTORC1 complex hydrolyses GTP (Gallus gallus)


name: LC3:ATG7 dimer binds ATG3 (Gallus gallus)


name: MTMR14, MTMR3 dephosphorylate PI3P (Gallus gallus)


name: ULK1 phosphorylates AMBRA1:BECN1 complex (Gallus gallus)


name: ATG10 transfers ATG12 from ATG10 to ATG5 (Gallus gallus)


name: ATG7:ATG3:LC3 dissociates (Gallus gallus)


name: ATG10 dissociates from ATG12:ATG5 (Gallus gallus)


name: ULK1 phosphorylates Beclin-1 (Gallus gallus)


name: Beclin-1 complex phosphorylates PtdIns (Gallus gallus)


name: p-AMPK:AMP binds the ULK complex (Gallus gallus)


name: ULK1 is dephosphorylated (Gallus gallus)


name: ULK1 phosphorylates ATG13 and RB1CC1 (Gallus gallus)


name: Active MTORC1 phosphorylates ULK1 (Gallus gallus)


name: ULK1 phosphorylates ATG13 and RB1CC1 (Drosophila melanogaster)


name: ATG7:ATG3:LC3 dissociates (Drosophila melanogaster)


name: MTORC1 dissociates from ULK complex (Drosophila melanogaster)


name: Autophagosome maturation (Drosophila melanogaster)


name: AMPK (complex) phosphorylates ULK1 (complex) (Drosophila melanogaster)


name: Rheb in the MTORC1 complex hydrolyses GTP (Drosophila melanogaster)


name: LC3 binds ATG7 dimer (Drosophila melanogaster)


name: Beclin-1 complex translocates to the ER (Drosophila melanogaster)


name: ATG12 binds ATG7 dimer (Drosophila melanogaster)


name: Active MTORC1 binds the ULK1 complex (Drosophila melanogaster)


name: MTMR14, MTMR3 dephosphorylate PI3P (Drosophila melanogaster)


name: The phagophore extends from the PIP3-enriched structure (Drosophila melanogaster)


name: WIPI2 binds ATG12:ATG5:ATG16L (Drosophila melanogaster)


name: LC3 is cleaved by ATG4 (Drosophila melanogaster)


name: Beclin-1 complex phosphorylates PtdIns (Drosophila melanogaster)


name: ULK complex translocates to the ER (Drosophila melanogaster)


name: ULK1 phosphorylates AMBRA1:BECN1 complex (Drosophila melanogaster)


name: p-AMPK:AMP binds the ULK complex (Drosophila melanogaster)


name: WIPIs bind PI3P (Drosophila melanogaster)


name: Active MTORC1 phosphorylates ULK1 (Drosophila melanogaster)


name: ULK1 phosphorylates Beclin-1 (Drosophila melanogaster)


name: ATG16L1 complex transfers LC3 from ATG3 to PE (Drosophila melanogaster)


name: LC3:ATG7 dimer binds ATG3 (Drosophila melanogaster)


name: p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex (Drosophila melanogaster)


name: LC3 de-lipidation by ATG4 (Drosophila melanogaster)


name: ATG3 transfers LC3 from ATG7 to ATG3 (Drosophila melanogaster)


name: ULK1 is dephosphorylated (Drosophila melanogaster)


name: Thr-180 of ULK1 is phosphorylated (Drosophila melanogaster)


name: ATG12 forms a thioester bond with ATG7 dimer (Drosophila melanogaster)


name: ULK1 phosphorylates AMBRA1:BECN1 complex (Caenorhabditis elegans)


name: MTORC1 dissociates from ULK complex (Caenorhabditis elegans)


name: Active MTORC1 binds the ULK1 complex (Caenorhabditis elegans)


name: Autophagosome maturation (Caenorhabditis elegans)


name: Beclin-1 complex phosphorylates PtdIns (Caenorhabditis elegans)


name: Rheb in the MTORC1 complex hydrolyses GTP (Caenorhabditis elegans)


name: LC3 binds ATG7 dimer (Caenorhabditis elegans)


name: p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex (Caenorhabditis elegans)


name: Beclin-1 complex translocates to the ER (Caenorhabditis elegans)


name: ATG12 binds ATG7 dimer (Caenorhabditis elegans)


name: ULK1 phosphorylates Beclin-1 (Caenorhabditis elegans)


name: ULK1 is dephosphorylated (Caenorhabditis elegans)


name: ATG7:ATG3:LC3 dissociates (Caenorhabditis elegans)


name: WIPI2 binds ATG12:ATG5:ATG16L (Caenorhabditis elegans)


name: LC3 is cleaved by ATG4 (Caenorhabditis elegans)


name: WIPIs bind PI3P (Caenorhabditis elegans)


name: p-AMPK:AMP binds the ULK complex (Caenorhabditis elegans)


name: ULK complex translocates to the ER (Caenorhabditis elegans)


name: Active MTORC1 phosphorylates ULK1 (Caenorhabditis elegans)


name: The phagophore extends from the PIP3-enriched structure (Caenorhabditis elegans)


name: ATG16L1 complex transfers LC3 from ATG3 to PE (Caenorhabditis elegans)


name: Thr-180 of ULK1 is phosphorylated (Caenorhabditis elegans)


name: LC3:ATG7 dimer binds ATG3 (Caenorhabditis elegans)


name: ATG12 forms a thioester bond with ATG7 dimer (Caenorhabditis elegans)


name: AMPK (complex) phosphorylates ULK1 (complex) (Caenorhabditis elegans)


name: ATG3 transfers LC3 from ATG7 to ATG3 (Caenorhabditis elegans)


name: ULK1 phosphorylates ATG13 and RB1CC1 (Caenorhabditis elegans)


name: LC3 de-lipidation by ATG4 (Caenorhabditis elegans)


name: MTORC1 dissociates from ULK complex (Dictyostelium discoideum)


name: ATG12 binds ATG7 dimer (Dictyostelium discoideum)


name: ATG16L1 complex transfers LC3 from ATG3 to PE (Dictyostelium discoideum)


name: WIPI2 binds ATG12:ATG5:ATG16L (Dictyostelium discoideum)


name: Beclin-1 complex translocates to the ER (Dictyostelium discoideum)


name: ULK1 phosphorylates Beclin-1 (Dictyostelium discoideum)


name: p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex (Dictyostelium discoideum)


name: Active MTORC1 binds the ULK1 complex (Dictyostelium discoideum)


name: ATG12 forms a thioester bond with ATG7 dimer (Dictyostelium discoideum)


name: MTMR14, MTMR3 dephosphorylate PI3P (Dictyostelium discoideum)


name: ULK complex translocates to the ER (Dictyostelium discoideum)


name: ATG7:ATG3:LC3 dissociates (Dictyostelium discoideum)


name: The phagophore extends from the PIP3-enriched structure (Dictyostelium discoideum)


name: ATG3 transfers LC3 from ATG7 to ATG3 (Dictyostelium discoideum)


name: Beclin-1 complex phosphorylates PtdIns (Dictyostelium discoideum)


name: WIPIs bind PI3P (Dictyostelium discoideum)


name: LC3:ATG7 dimer binds ATG3 (Dictyostelium discoideum)


name: AMPK (complex) phosphorylates ULK1 (complex) (Dictyostelium discoideum)


name: Rheb in the MTORC1 complex hydrolyses GTP (Dictyostelium discoideum)


name: LC3 de-lipidation by ATG4 (Dictyostelium discoideum)


name: ULK1 is dephosphorylated (Dictyostelium discoideum)


name: LC3 binds ATG7 dimer (Dictyostelium discoideum)


name: Active MTORC1 phosphorylates ULK1 (Dictyostelium discoideum)


name: p-AMPK:AMP binds the ULK complex (Dictyostelium discoideum)


name: Thr-180 of ULK1 is phosphorylated (Dictyostelium discoideum)


name: ULK1 phosphorylates ATG13 and RB1CC1 (Dictyostelium discoideum)


name: Autophagosome maturation (Dictyostelium discoideum)


name: LC3 is cleaved by ATG4 (Dictyostelium discoideum)


name: WIPIs bind PI3P (Schizosaccharomyces pombe)


name: ULK1 phosphorylates Beclin-1 (Schizosaccharomyces pombe)


name: MTMR14, MTMR3 dephosphorylate PI3P (Schizosaccharomyces pombe)


name: Autophagosome maturation (Schizosaccharomyces pombe)


name: ULK complex translocates to the ER (Schizosaccharomyces pombe)


name: AMPK (complex) phosphorylates ULK1 (complex) (Schizosaccharomyces pombe)


name: LC3:ATG7 dimer binds ATG3 (Schizosaccharomyces pombe)


name: Beclin-1 complex translocates to the ER (Schizosaccharomyces pombe)


name: ULK1 phosphorylates ATG13 and RB1CC1 (Schizosaccharomyces pombe)


name: ULK1 is dephosphorylated (Schizosaccharomyces pombe)


name: ULK1 phosphorylates AMBRA1:BECN1 complex (Schizosaccharomyces pombe)


name: Beclin-1 complex phosphorylates PtdIns (Schizosaccharomyces pombe)


name: ATG16L1 complex transfers LC3 from ATG3 to PE (Schizosaccharomyces pombe)


name: ATG7:ATG3:LC3 dissociates (Schizosaccharomyces pombe)


name: Thr-180 of ULK1 is phosphorylated (Schizosaccharomyces pombe)


name: ATG12 forms a thioester bond with ATG7 dimer (Schizosaccharomyces pombe)


name: LC3 binds ATG7 dimer (Schizosaccharomyces pombe)


name: p-AMPK:AMP binds the ULK complex (Schizosaccharomyces pombe)


name: ATG3 transfers LC3 from ATG7 to ATG3 (Schizosaccharomyces pombe)


name: ATG12 binds ATG7 dimer (Schizosaccharomyces pombe)


name: The phagophore extends from the PIP3-enriched structure (Schizosaccharomyces pombe)


name: ATG7:ATG3:LC3 dissociates (Saccharomyces cerevisiae)


name: LC3 binds ATG7 dimer (Saccharomyces cerevisiae)


name: ATG16L1 complex transfers LC3 from ATG3 to PE (Saccharomyces cerevisiae)


name: ULK1 phosphorylates ATG13 and RB1CC1 (Saccharomyces cerevisiae)


name: Beclin-1 complex translocates to the ER (Saccharomyces cerevisiae)


name: ATG3 transfers LC3 from ATG7 to ATG3 (Saccharomyces cerevisiae)


name: Thr-180 of ULK1 is phosphorylated (Saccharomyces cerevisiae)


name: The phagophore extends from the PIP3-enriched structure (Saccharomyces cerevisiae)


name: ATG12 binds ATG7 dimer (Saccharomyces cerevisiae)


name: p-AMPK:AMP binds the ULK complex (Saccharomyces cerevisiae)


name: ULK1 is dephosphorylated (Saccharomyces cerevisiae)


name: MTMR14, MTMR3 dephosphorylate PI3P (Saccharomyces cerevisiae)


name: Autophagosome maturation (Saccharomyces cerevisiae)


name: WIPIs bind PI3P (Saccharomyces cerevisiae)


name: ULK complex translocates to the ER (Saccharomyces cerevisiae)


name: LC3:ATG7 dimer binds ATG3 (Saccharomyces cerevisiae)


name: AMPK (complex) phosphorylates ULK1 (complex) (Saccharomyces cerevisiae)


name: Beclin-1 complex phosphorylates PtdIns (Saccharomyces cerevisiae)


name: ATG12 forms a thioester bond with ATG7 dimer (Saccharomyces cerevisiae)


name: ULK1 phosphorylates Beclin-1 (Saccharomyces cerevisiae)


name: ATG7:ATG3:LC3 dissociates (Plasmodium falciparum)


name: LC3 is cleaved by ATG4 (Plasmodium falciparum)


name: Autophagosome maturation (Plasmodium falciparum)


name: LC3 de-lipidation by ATG4 (Plasmodium falciparum)


name: LC3 binds ATG7 dimer (Plasmodium falciparum)


name: ATG3 transfers LC3 from ATG7 to ATG3 (Plasmodium falciparum)


name: ATG12 binds ATG7 dimer (Plasmodium falciparum)


name: ATG12 forms a thioester bond with ATG7 dimer (Plasmodium falciparum)


name: LC3:ATG7 dimer binds ATG3 (Plasmodium falciparum)


late endosomal microautophagy

description: The autophagy process by which cytosolic proteins targeted for degradation are tagged with a chaperone and are directly transferred into and degraded in a late endosomal compartment.


name: HSPA8:substrate binds late endosomal phospholipids (Homo sapiens)


name: Substrate translocates into late endosomal lumen (Homo sapiens)


name: Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal (Homo sapiens)


name: Release of activated MAD2 from kinetochores (Homo sapiens)


name: MAD2 converted  to an inhibitory state via interaction with Mad1 (Homo sapiens)


name: MAD2 associates with the Mad1 kinetochore complex (Homo sapiens)


name: Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal (Mus musculus)


name: MAD2 associates with the Mad1 kinetochore complex (Mus musculus)


name: Release of activated MAD2 from kinetochores (Mus musculus)


name: MAD2 converted  to an inhibitory state via interaction with Mad1 (Mus musculus)


name: Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal (Rattus norvegicus)


name: MAD2 converted  to an inhibitory state via interaction with Mad1 (Rattus norvegicus)


name: Release of activated MAD2 from kinetochores (Rattus norvegicus)


name: Mad1 binds kinetochore (Rattus norvegicus)


name: MAD2 associates with the Mad1 kinetochore complex (Rattus norvegicus)


name: Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal (Canis familiaris)


name: MAD2 associates with the Mad1 kinetochore complex (Canis familiaris)


name: MAD2 converted  to an inhibitory state via interaction with Mad1 (Canis familiaris)


name: Mad1 binds kinetochore (Canis familiaris)


name: Release of activated MAD2 from kinetochores (Canis familiaris)


name: Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal (Bos taurus)


name: MAD2 associates with the Mad1 kinetochore complex (Bos taurus)


name: MAD2 converted  to an inhibitory state via interaction with Mad1 (Bos taurus)


name: Release of activated MAD2 from kinetochores (Bos taurus)


name: Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal (Sus scrofa)


name: Release of activated MAD2 from kinetochores (Sus scrofa)


name: MAD2 converted  to an inhibitory state via interaction with Mad1 (Sus scrofa)


name: MAD2 associates with the Mad1 kinetochore complex (Sus scrofa)


name: Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal (Xenopus tropicalis)


name: Release of activated MAD2 from kinetochores (Xenopus tropicalis)


name: Mad1 binds kinetochore (Xenopus tropicalis)


name: MAD2 associates with the Mad1 kinetochore complex (Xenopus tropicalis)


name: MAD2 converted  to an inhibitory state via interaction with Mad1 (Xenopus tropicalis)


name: Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal (Gallus gallus)


name: Release of activated MAD2 from kinetochores (Gallus gallus)


name: MAD2 converted  to an inhibitory state via interaction with Mad1 (Gallus gallus)


name: MAD2 associates with the Mad1 kinetochore complex (Gallus gallus)


name: Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components (Homo sapiens)


name: Inactivation of APC/C via CDC20 sequestration (Homo sapiens)


name: Inactivation of APC/C via direct inhibition of the APC/C complex (Homo sapiens)


name: Formation of the MCC complex (Homo sapiens)


name: Binding of the MCC complex to the APC/C complex (Homo sapiens)


name: Inactivation of APC/C via direct inhibition of the APC/C complex (Mus musculus)


name: Formation of the MCC complex (Mus musculus)


name: Binding of the MCC complex to the APC/C complex (Mus musculus)


name: Inactivation of APC/C via direct inhibition of the APC/C complex (Rattus norvegicus)


name: Binding of the MCC complex to the APC/C complex (Rattus norvegicus)


name: Inactivation of APC/C via direct inhibition of the APC/C complex (Canis familiaris)


name: Binding of the MCC complex to the APC/C complex (Canis familiaris)


name: Formation of the MCC complex (Canis familiaris)


name: Inactivation of APC/C via direct inhibition of the APC/C complex (Bos taurus)


name: Formation of the MCC complex (Bos taurus)


name: Binding of the MCC complex to the APC/C complex (Bos taurus)


name: Inactivation of APC/C via direct inhibition of the APC/C complex (Sus scrofa)


name: Binding of the MCC complex to the APC/C complex (Sus scrofa)


name: Formation of the MCC complex (Sus scrofa)


name: Inactivation of APC/C via direct inhibition of the APC/C complex (Xenopus tropicalis)


name: Formation of the MCC complex (Xenopus tropicalis)


name: Binding of the MCC complex to the APC/C complex (Xenopus tropicalis)


name: Inactivation of APC/C via direct inhibition of the APC/C complex (Gallus gallus)


name: Binding of the MCC complex to the APC/C complex (Gallus gallus)


name: Formation of the MCC complex (Gallus gallus)


name: Inactivation of APC/C via direct inhibition of the APC/C complex (Drosophila melanogaster)


name: Formation of the MCC complex (Drosophila melanogaster)


name: Binding of the MCC complex to the APC/C complex (Drosophila melanogaster)


name: Inactivation of APC/C via direct inhibition of the APC/C complex (Caenorhabditis elegans)


name: Formation of the MCC complex (Caenorhabditis elegans)


name: Inactivation of APC/C via direct inhibition of the APC/C complex (Dictyostelium discoideum)


name: Formation of the MCC complex (Dictyostelium discoideum)


name: Binding of the MCC complex to the APC/C complex (Dictyostelium discoideum)


name: Inactivation of APC/C via direct inhibition of the APC/C complex (Schizosaccharomyces pombe)


name: Formation of the MCC complex (Schizosaccharomyces pombe)


name: Inactivation of APC/C via direct inhibition of the APC/C complex (Saccharomyces cerevisiae)


name: Formation of the MCC complex (Saccharomyces cerevisiae)


name: Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components (Mus musculus)


name: Inactivation of APC/C via CDC20 sequestration (Mus musculus)


name: Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components (Rattus norvegicus)


name: Inactivation of APC/C via CDC20 sequestration (Rattus norvegicus)


name: Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components (Canis familiaris)


name: Inactivation of APC/C via CDC20 sequestration (Canis familiaris)


name: Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components (Bos taurus)


name: Inactivation of APC/C via CDC20 sequestration (Bos taurus)


name: Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components (Sus scrofa)


name: Inactivation of APC/C via CDC20 sequestration (Sus scrofa)


name: Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components (Danio rerio)


name: Inactivation of APC/C via CDC20 sequestration (Danio rerio)


name: Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components (Xenopus tropicalis)


name: Inactivation of APC/C via CDC20 sequestration (Xenopus tropicalis)


name: Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components (Gallus gallus)


name: Inactivation of APC/C via CDC20 sequestration (Gallus gallus)


name: Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components (Drosophila melanogaster)


name: Inactivation of APC/C via CDC20 sequestration (Drosophila melanogaster)


name: Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components (Caenorhabditis elegans)


name: Inactivation of APC/C via CDC20 sequestration (Caenorhabditis elegans)


name: Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components (Dictyostelium discoideum)


name: Inactivation of APC/C via CDC20 sequestration (Dictyostelium discoideum)


name: Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components (Schizosaccharomyces pombe)


name: Inactivation of APC/C via CDC20 sequestration (Schizosaccharomyces pombe)


name: Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components (Saccharomyces cerevisiae)


name: Inactivation of APC/C via CDC20 sequestration (Saccharomyces cerevisiae)


name: GTSE1 promotes translocation of TP53 to the cytosol (Homo sapiens)


name: GTSE1 facilitates proteasome-mediated degradation of TP53 (Homo sapiens)


name: G2/M DNA damage checkpoint (Homo sapiens)


name: CHEK1 phosphorylates TP53 (Homo sapiens)


name: p-T68-CHEK2 autophosphorylates (Homo sapiens)


name: Recruitment and activation of Chk1 (Homo sapiens)


name: Phosphorylation and activation of CHEK2 by ATM (Homo sapiens)


name: CHEK2 is recruited to DNA DSBs (Homo sapiens)


name: Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex (Homo sapiens)


name: p-S216-CDC25C translocates to the cytosol (Homo sapiens)


name: Association of p-S216-CDC25C with 14-3-3 proteins (Homo sapiens)


name: Phosphorylation of Wee1 kinase by Chk1 (Homo sapiens)


name: Wee1-mediated phosphorylation of Cyclin B1:phospho-Cdc2 complexes (Homo sapiens)


name: Phosphorylation of Cdc25C at Ser216 by CHEK2 (Homo sapiens)


name: Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex (Mus musculus)


name: Wee1-mediated phosphorylation of Cyclin B1:phospho-Cdc2 complexes (Mus musculus)


name: Phosphorylation of Cdc25C at Ser216 by CHEK2 (Mus musculus)


name: Association of p-S216-CDC25C with 14-3-3 proteins (Mus musculus)


name: p-S216-CDC25C translocates to the cytosol (Mus musculus)


name: Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex (Rattus norvegicus)


name: Association of p-S216-CDC25C with 14-3-3 proteins (Rattus norvegicus)


name: Wee1-mediated phosphorylation of Cyclin B1:phospho-Cdc2 complexes (Rattus norvegicus)


name: Phosphorylation of Cdc25C at Ser216 by CHEK2 (Rattus norvegicus)


name: p-S216-CDC25C translocates to the cytosol (Rattus norvegicus)


name: Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex (Canis familiaris)


name: Wee1-mediated phosphorylation of Cyclin B1:phospho-Cdc2 complexes (Canis familiaris)


name: p-S216-CDC25C translocates to the cytosol (Canis familiaris)


name: Association of p-S216-CDC25C with 14-3-3 proteins (Canis familiaris)


name: Phosphorylation of Cdc25C at Ser216 by CHEK2 (Canis familiaris)


name: Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex (Bos taurus)


name: Wee1-mediated phosphorylation of Cyclin B1:phospho-Cdc2 complexes (Bos taurus)


name: Phosphorylation of Cdc25C at Ser216 by CHEK2 (Bos taurus)


name: p-S216-CDC25C translocates to the cytosol (Bos taurus)


name: Association of p-S216-CDC25C with 14-3-3 proteins (Bos taurus)


name: Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex (Sus scrofa)


name: Phosphorylation of Cdc25C at Ser216 by CHEK2 (Sus scrofa)


name: Wee1-mediated phosphorylation of Cyclin B1:phospho-Cdc2 complexes (Sus scrofa)


name: Association of p-S216-CDC25C with 14-3-3 proteins (Sus scrofa)


name: p-S216-CDC25C translocates to the cytosol (Sus scrofa)


name: Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex (Danio rerio)


name: Wee1-mediated phosphorylation of Cyclin B1:phospho-Cdc2 complexes (Danio rerio)


name: Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex (Xenopus tropicalis)


name: Wee1-mediated phosphorylation of Cyclin B1:phospho-Cdc2 complexes (Xenopus tropicalis)


name: Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex (Drosophila melanogaster)


name: p-S216-CDC25C translocates to the cytosol (Drosophila melanogaster)


name: Phosphorylation of Cdc25C at Ser216 by CHEK2 (Drosophila melanogaster)


name: Wee1-mediated phosphorylation of Cyclin B1:phospho-Cdc2 complexes (Drosophila melanogaster)


name: Association of p-S216-CDC25C with 14-3-3 proteins (Drosophila melanogaster)


name: Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex (Caenorhabditis elegans)


name: Phosphorylation of Cdc25C at Ser216 by CHEK2 (Caenorhabditis elegans)


name: p-S216-CDC25C translocates to the cytosol (Caenorhabditis elegans)


name: Association of p-S216-CDC25C with 14-3-3 proteins (Caenorhabditis elegans)


name: Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex (Dictyostelium discoideum)


name: Phosphorylation of Cdc25C at Ser216 by CHEK2 (Dictyostelium discoideum)


name: Association of p-S216-CDC25C with 14-3-3 proteins (Dictyostelium discoideum)


name: p-S216-CDC25C translocates to the cytosol (Dictyostelium discoideum)


name: Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex (Schizosaccharomyces pombe)


name: Association of p-S216-CDC25C with 14-3-3 proteins (Schizosaccharomyces pombe)


name: p-S216-CDC25C translocates to the cytosol (Schizosaccharomyces pombe)


name: Phosphorylation of Cdc25C at Ser216 by CHEK2 (Schizosaccharomyces pombe)


name: Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex (Saccharomyces cerevisiae)


name: Association of p-S216-CDC25C with 14-3-3 proteins (Saccharomyces cerevisiae)


name: Phosphorylation of Cdc25C at Ser216 by CHEK2 (Saccharomyces cerevisiae)


name: p-S216-CDC25C translocates to the cytosol (Saccharomyces cerevisiae)


name: G2/M DNA damage checkpoint (Mus musculus)


name: Phosphorylation and activation of CHEK2 by ATM (Mus musculus)


name: CHEK2 is recruited to DNA DSBs (Mus musculus)


name: CHEK1 phosphorylates TP53 (Mus musculus)


name: p-T68-CHEK2 autophosphorylates (Mus musculus)


name: Recruitment and activation of Chk1 (Mus musculus)


name: G2/M DNA damage checkpoint (Rattus norvegicus)


name: p-T68-CHEK2 dimerizes (Rattus norvegicus)


name: ATR phosphorylates TP53 (Rattus norvegicus)


name: Recruitment and activation of Chk1 (Rattus norvegicus)


name: CHEK2 is recruited to DNA DSBs (Rattus norvegicus)


name: CHEK1 phosphorylates TP53 (Rattus norvegicus)


name: Phosphorylation and activation of CHEK2 by ATM (Rattus norvegicus)


name: p-T68-CHEK2 autophosphorylates (Rattus norvegicus)


name: G2/M DNA damage checkpoint (Canis familiaris)


name: p-T68-CHEK2 dimerizes (Canis familiaris)


name: CHEK2 is recruited to DNA DSBs (Canis familiaris)


name: Phosphorylation and activation of CHEK2 by ATM (Canis familiaris)


name: ATR phosphorylates TP53 (Canis familiaris)


name: Recruitment and activation of Chk1 (Canis familiaris)


name: CHEK1 phosphorylates TP53 (Canis familiaris)


name: p-T68-CHEK2 autophosphorylates (Canis familiaris)


name: Phosphorylation and activation of CHEK2 by ATM (Bos taurus)


name: CHEK2 is recruited to DNA DSBs (Bos taurus)


name: p-T68-CHEK2 autophosphorylates (Bos taurus)


name: Phosphorylation and activation of CHEK2 by ATM (Sus scrofa)


name: CHEK2 is recruited to DNA DSBs (Sus scrofa)


name: Recruitment and activation of Chk1 (Sus scrofa)


name: p-T68-CHEK2 autophosphorylates (Sus scrofa)


name: G2/M DNA damage checkpoint (Xenopus tropicalis)


name: p-T68-CHEK2 autophosphorylates (Xenopus tropicalis)


name: ATR phosphorylates TP53 (Xenopus tropicalis)


name: p-T68-CHEK2 dimerizes (Xenopus tropicalis)


name: G2/M DNA damage checkpoint (Gallus gallus)


name: CHEK2 is recruited to DNA DSBs (Gallus gallus)


name: Phosphorylation and activation of CHEK2 by ATM (Gallus gallus)


name: p-T68-CHEK2 autophosphorylates (Gallus gallus)


name: G2/M DNA damage checkpoint (Drosophila melanogaster)


name: CHEK1 phosphorylates TP53 (Drosophila melanogaster)


name: ATR phosphorylates TP53 (Drosophila melanogaster)


name: p-T68-CHEK2 dimerizes (Drosophila melanogaster)


name: Recruitment and activation of Chk1 (Drosophila melanogaster)


name: p-T68-CHEK2 autophosphorylates (Drosophila melanogaster)


name: G2/M DNA damage checkpoint (Caenorhabditis elegans)


name: p-T68-CHEK2 autophosphorylates (Caenorhabditis elegans)


name: p-T68-CHEK2 dimerizes (Caenorhabditis elegans)


name: G2/M DNA damage checkpoint (Dictyostelium discoideum)


name: p-T68-CHEK2 autophosphorylates (Dictyostelium discoideum)


name: p-T68-CHEK2 dimerizes (Dictyostelium discoideum)


name: G2/M DNA damage checkpoint (Schizosaccharomyces pombe)


name: p-T68-CHEK2 dimerizes (Schizosaccharomyces pombe)


name: p-T68-CHEK2 autophosphorylates (Schizosaccharomyces pombe)


name: G2/M DNA damage checkpoint (Saccharomyces cerevisiae)


name: p-T68-CHEK2 dimerizes (Saccharomyces cerevisiae)


name: p-T68-CHEK2 autophosphorylates (Saccharomyces cerevisiae)


name: G2/M DNA damage checkpoint (Plasmodium falciparum)


name: p-T68-CHEK2 dimerizes (Plasmodium falciparum)


name: p-T68-CHEK2 autophosphorylates (Plasmodium falciparum)


name: G2/M DNA replication checkpoint (Homo sapiens)


name: Myt-1 mediated phosphorylation of Cyclin B:Cdc2 complexes (Homo sapiens)


name: G2/M DNA replication checkpoint (Mus musculus)


name: Myt-1 mediated phosphorylation of Cyclin B:Cdc2 complexes (Mus musculus)


name: G2/M DNA replication checkpoint (Rattus norvegicus)


name: Myt-1 mediated phosphorylation of Cyclin B:Cdc2 complexes (Rattus norvegicus)


name: G2/M DNA replication checkpoint (Canis familiaris)


name: Myt-1 mediated phosphorylation of Cyclin B:Cdc2 complexes (Canis familiaris)


name: G2/M DNA replication checkpoint (Bos taurus)


name: Myt-1 mediated phosphorylation of Cyclin B:Cdc2 complexes (Bos taurus)


name: G2/M DNA replication checkpoint (Sus scrofa)


name: Myt-1 mediated phosphorylation of Cyclin B:Cdc2 complexes (Sus scrofa)


name: G2/M DNA replication checkpoint (Danio rerio)


name: Myt-1 mediated phosphorylation of Cyclin B:Cdc2 complexes (Danio rerio)


name: G2/M DNA replication checkpoint (Xenopus tropicalis)


name: G2/M DNA replication checkpoint (Drosophila melanogaster)


name: Myt-1 mediated phosphorylation of Cyclin B:Cdc2 complexes (Drosophila melanogaster)


name: G2/M DNA replication checkpoint (Caenorhabditis elegans)


name: Myt-1 mediated phosphorylation of Cyclin B:Cdc2 complexes (Caenorhabditis elegans)


name: Activation of ATR in response to replication stress (Homo sapiens)


name: Stalling of DNA replication fork and RPA binding (Homo sapiens)


name: Loading of claspin onto DNA during replication origin firing (Homo sapiens)


name: Recruitment of the Rad9-Hus1-Rad1 complex to DNA (Homo sapiens)


name: Binding of ATR-ATRIP to the RPA-ssDNA complex (Homo sapiens)


name: Recruitment of Rad17-RFC complex to DNA (Homo sapiens)


name: Phosphorylation of Cdc25A at Ser-123 by Chk1 (Homo sapiens)


name: Phosphorylation of Cdc25C at Ser 216 by Chk1 (Homo sapiens)


name: Activation of ATR in response to replication stress (Mus musculus)


name: Recruitment of Rad17-RFC complex to DNA (Mus musculus)


name: Stalling of DNA replication fork and RPA binding (Mus musculus)


name: Binding of ATR-ATRIP to the RPA-ssDNA complex (Mus musculus)


name: Phosphorylation of Cdc25A at Ser-123 by Chk1 (Mus musculus)


name: Phosphorylation of Cdc25C at Ser 216 by Chk1 (Mus musculus)


name: Loading of claspin onto DNA during replication origin firing (Mus musculus)


name: Recruitment of the Rad9-Hus1-Rad1 complex to DNA (Mus musculus)


name: Activation of ATR in response to replication stress (Rattus norvegicus)


name: Phosphorylation of Cdc25C at Ser 216 by Chk1 (Rattus norvegicus)


name: Phosphorylation of Cdc25A at Ser-123 by Chk1 (Rattus norvegicus)


name: Stalling of DNA replication fork and RPA binding (Rattus norvegicus)


name: Recruitment of the Rad9-Hus1-Rad1 complex to DNA (Rattus norvegicus)


name: Loading of claspin onto DNA during replication origin firing (Rattus norvegicus)


name: Recruitment of Rad17-RFC complex to DNA (Rattus norvegicus)


name: Activation of claspin (Rattus norvegicus)


name: Binding of ATR-ATRIP to the RPA-ssDNA complex (Rattus norvegicus)


name: Activation of ATR in response to replication stress (Canis familiaris)


name: Binding of ATR-ATRIP to the RPA-ssDNA complex (Canis familiaris)


name: Phosphorylation of Cdc25A at Ser-123 by Chk1 (Canis familiaris)


name: Stalling of DNA replication fork and RPA binding (Canis familiaris)


name: Phosphorylation of Cdc25C at Ser 216 by Chk1 (Canis familiaris)


name: Loading of claspin onto DNA during replication origin firing (Canis familiaris)


name: Recruitment of the Rad9-Hus1-Rad1 complex to DNA (Canis familiaris)


name: Recruitment of Rad17-RFC complex to DNA (Canis familiaris)


name: Activation of claspin (Canis familiaris)


name: Activation of ATR in response to replication stress (Bos taurus)


name: Loading of claspin onto DNA during replication origin firing (Bos taurus)


name: Recruitment of the Rad9-Hus1-Rad1 complex to DNA (Bos taurus)


name: Stalling of DNA replication fork and RPA binding (Bos taurus)


name: Recruitment of Rad17-RFC complex to DNA (Bos taurus)


name: Binding of ATR-ATRIP to the RPA-ssDNA complex (Bos taurus)


name: Activation of ATR in response to replication stress (Sus scrofa)


name: Binding of ATR-ATRIP to the RPA-ssDNA complex (Sus scrofa)


name: Loading of claspin onto DNA during replication origin firing (Sus scrofa)


name: Recruitment of the Rad9-Hus1-Rad1 complex to DNA (Sus scrofa)


name: Phosphorylation of Cdc25C at Ser 216 by Chk1 (Sus scrofa)


name: Phosphorylation of Cdc25A at Ser-123 by Chk1 (Sus scrofa)


name: Stalling of DNA replication fork and RPA binding (Sus scrofa)


name: Recruitment of Rad17-RFC complex to DNA (Sus scrofa)


name: Activation of ATR in response to replication stress (Danio rerio)


name: Recruitment of Rad17-RFC complex to DNA (Danio rerio)


name: Stalling of DNA replication fork and RPA binding (Danio rerio)


name: Activation of ATR in response to replication stress (Xenopus tropicalis)


name: Stalling of DNA replication fork and RPA binding (Xenopus tropicalis)


name: Recruitment of Rad17-RFC complex to DNA (Xenopus tropicalis)


name: Recruitment of the Rad9-Hus1-Rad1 complex to DNA (Xenopus tropicalis)


name: Activation of ATR in response to replication stress (Gallus gallus)


name: Loading of claspin onto DNA during replication origin firing (Gallus gallus)


name: Recruitment of the Rad9-Hus1-Rad1 complex to DNA (Gallus gallus)


name: Stalling of DNA replication fork and RPA binding (Gallus gallus)


name: Recruitment of Rad17-RFC complex to DNA (Gallus gallus)


name: Binding of ATR-ATRIP to the RPA-ssDNA complex (Gallus gallus)


name: Activation of ATR in response to replication stress (Drosophila melanogaster)


name: Phosphorylation of Cdc25C at Ser 216 by Chk1 (Drosophila melanogaster)


name: Binding of ATR-ATRIP to the RPA-ssDNA complex (Drosophila melanogaster)


name: Phosphorylation of Cdc25A at Ser-123 by Chk1 (Drosophila melanogaster)


name: Stalling of DNA replication fork and RPA binding (Drosophila melanogaster)


name: Activation of claspin (Drosophila melanogaster)


name: Recruitment of the Rad9-Hus1-Rad1 complex to DNA (Drosophila melanogaster)


name: Loading of claspin onto DNA during replication origin firing (Drosophila melanogaster)


name: Recruitment of Rad17-RFC complex to DNA (Drosophila melanogaster)


name: Activation of ATR in response to replication stress (Caenorhabditis elegans)


name: Phosphorylation of Cdc25C at Ser 216 by Chk1 (Caenorhabditis elegans)


name: Phosphorylation of Cdc25A at Ser-123 by Chk1 (Caenorhabditis elegans)


name: Recruitment of the Rad9-Hus1-Rad1 complex to DNA (Caenorhabditis elegans)


name: Activation of ATR in response to replication stress (Dictyostelium discoideum)


name: Recruitment of the Rad9-Hus1-Rad1 complex to DNA (Dictyostelium discoideum)


name: Activation of ATR in response to replication stress (Schizosaccharomyces pombe)


name: Phosphorylation of Cdc25A at Ser-123 by Chk1 (Schizosaccharomyces pombe)


name: Recruitment of the Rad9-Hus1-Rad1 complex to DNA (Schizosaccharomyces pombe)


name: Loading of claspin onto DNA during replication origin firing (Schizosaccharomyces pombe)


name: Recruitment of Rad17-RFC complex to DNA (Schizosaccharomyces pombe)


name: Stalling of DNA replication fork and RPA binding (Schizosaccharomyces pombe)


name: Phosphorylation of Cdc25C at Ser 216 by Chk1 (Schizosaccharomyces pombe)


name: Activation of ATR in response to replication stress (Saccharomyces cerevisiae)


name: Phosphorylation of Cdc25A at Ser-123 by Chk1 (Saccharomyces cerevisiae)


name: Loading of claspin onto DNA during replication origin firing (Saccharomyces cerevisiae)


name: Phosphorylation of Cdc25C at Ser 216 by Chk1 (Saccharomyces cerevisiae)


name: Recruitment of the Rad9-Hus1-Rad1 complex to DNA (Saccharomyces cerevisiae)


name: Activation of ATR in response to replication stress (Plasmodium falciparum)


name: Recruitment of Rad17-RFC complex to DNA (Plasmodium falciparum)


name: Stalling of DNA replication fork and RPA binding (Plasmodium falciparum)


G2 Phase (Homo sapiens)

definition: One of two 'gap' phases in the standard eukaryotic mitotic cell cycle; the interval between the completion of DNA synthesis and the beginning of mitosis.


name: Phosphorylation of E2F1/E2F3 by Cyclin A:phosph-Cdk2(Thr 160) (Homo sapiens)


name: Association of Cyclin A:phospho-Cdk2(Thr 160) with E2F1/E2F3 (Homo sapiens)


name: Establishment of Sister Chromatid Cohesion (Homo sapiens)


name: CDCA5 (Sororin) enables cohesion of sister chromosomal arms (Homo sapiens)


name: CDCA5 (Sororin) enables cohesion of sister centromeres (Homo sapiens)


name: Acetylation of SMC3 subunit of centromeric chromatin associated cohesin by ESCO1 or ESCO2 (Homo sapiens)


name: Acetylation of SMC3 subunit of chromosomal arm associated cohesin by ESCO1 or ESCO2 (Homo sapiens)


name: Establishment of Sister Chromatid Cohesion (Mus musculus)


name: Acetylation of SMC3 subunit of chromosomal arm associated cohesin by ESCO1 or ESCO2 (Mus musculus)


name: CDCA5 (Sororin) enables cohesion of sister chromosomal arms (Mus musculus)


name: Acetylation of SMC3 subunit of centromeric chromatin associated cohesin by ESCO1 or ESCO2 (Mus musculus)


name: CDCA5 (Sororin) enables cohesion of sister centromeres (Mus musculus)


name: Establishment of Sister Chromatid Cohesion (Rattus norvegicus)


name: CDCA5 (Sororin) enables cohesion of sister centromeres (Rattus norvegicus)


name: Acetylation of SMC3 subunit of chromosomal arm associated cohesin by ESCO1 or ESCO2 (Rattus norvegicus)


name: CDCA5 (Sororin) enables cohesion of sister chromosomal arms (Rattus norvegicus)


name: Acetylation of SMC3 subunit of centromeric chromatin associated cohesin by ESCO1 or ESCO2 (Rattus norvegicus)


name: Establishment of Sister Chromatid Cohesion (Canis familiaris)


name: Acetylation of SMC3 subunit of chromosomal arm associated cohesin by ESCO1 or ESCO2 (Canis familiaris)


name: CDCA5 (Sororin) enables cohesion of sister chromosomal arms (Canis familiaris)


name: Acetylation of SMC3 subunit of centromeric chromatin associated cohesin by ESCO1 or ESCO2 (Canis familiaris)


name: CDCA5 (Sororin) enables cohesion of sister centromeres (Canis familiaris)


name: Establishment of Sister Chromatid Cohesion (Bos taurus)


name: Acetylation of SMC3 subunit of chromosomal arm associated cohesin by ESCO1 or ESCO2 (Bos taurus)


name: CDCA5 (Sororin) enables cohesion of sister centromeres (Bos taurus)


name: Acetylation of SMC3 subunit of centromeric chromatin associated cohesin by ESCO1 or ESCO2 (Bos taurus)


name: CDCA5 (Sororin) enables cohesion of sister chromosomal arms (Bos taurus)


name: Establishment of Sister Chromatid Cohesion (Sus scrofa)


name: CDCA5 (Sororin) enables cohesion of sister chromosomal arms (Sus scrofa)


name: Acetylation of SMC3 subunit of centromeric chromatin associated cohesin by ESCO1 or ESCO2 (Sus scrofa)


name: Acetylation of SMC3 subunit of chromosomal arm associated cohesin by ESCO1 or ESCO2 (Sus scrofa)


name: CDCA5 (Sororin) enables cohesion of sister centromeres (Sus scrofa)


name: Establishment of Sister Chromatid Cohesion (Danio rerio)


name: Acetylation of SMC3 subunit of chromosomal arm associated cohesin by ESCO1 or ESCO2 (Danio rerio)


name: Acetylation of SMC3 subunit of centromeric chromatin associated cohesin by ESCO1 or ESCO2 (Danio rerio)


name: Establishment of Sister Chromatid Cohesion (Gallus gallus)


name: Acetylation of SMC3 subunit of chromosomal arm associated cohesin by ESCO1 or ESCO2 (Gallus gallus)


name: Acetylation of SMC3 subunit of centromeric chromatin associated cohesin by ESCO1 or ESCO2 (Gallus gallus)


name: Establishment of Sister Chromatid Cohesion (Drosophila melanogaster)


name: Acetylation of SMC3 subunit of chromosomal arm associated cohesin by ESCO1 or ESCO2 (Drosophila melanogaster)


name: Acetylation of SMC3 subunit of centromeric chromatin associated cohesin by ESCO1 or ESCO2 (Drosophila melanogaster)


name: Establishment of Sister Chromatid Cohesion (Caenorhabditis elegans)


name: Acetylation of SMC3 subunit of chromosomal arm associated cohesin by ESCO1 or ESCO2 (Caenorhabditis elegans)


name: Acetylation of SMC3 subunit of centromeric chromatin associated cohesin by ESCO1 or ESCO2 (Caenorhabditis elegans)


name: Establishment of Sister Chromatid Cohesion (Dictyostelium discoideum)


name: Acetylation of SMC3 subunit of centromeric chromatin associated cohesin by ESCO1 or ESCO2 (Dictyostelium discoideum)


name: Acetylation of SMC3 subunit of chromosomal arm associated cohesin by ESCO1 or ESCO2 (Dictyostelium discoideum)


name: Establishment of Sister Chromatid Cohesion (Saccharomyces cerevisiae)


name: Acetylation of SMC3 subunit of centromeric chromatin associated cohesin by ESCO1 or ESCO2 (Saccharomyces cerevisiae)


name: Acetylation of SMC3 subunit of chromosomal arm associated cohesin by ESCO1 or ESCO2 (Saccharomyces cerevisiae)


name: RFC dissociates after sliding clamp formation (Homo sapiens)


name: RFC binding displaces Pol Alpha (Homo sapiens)


name: Loading of PCNA - Sliding Clamp Formation (Homo sapiens)


name: Formation of Processive Complex (Homo sapiens)


name: Loading of PCNA - Sliding Clamp Formation (Mus musculus)


name: RFC dissociates after sliding clamp formation (Mus musculus)


name: RFC binding displaces Pol Alpha (Mus musculus)


name: Formation of Processive Complex (Mus musculus)


name: Polymerase switching (Rattus norvegicus)


name: Loading of PCNA - Sliding Clamp Formation (Rattus norvegicus)


name: Formation of Processive Complex (Rattus norvegicus)


name: RFC dissociates after sliding clamp formation (Rattus norvegicus)


name: RFC binding displaces Pol Alpha (Rattus norvegicus)


name: RFC dissociates after sliding clamp formation (Canis familiaris)


name: Formation of Processive Complex (Canis familiaris)


name: Loading of PCNA - Sliding Clamp Formation (Canis familiaris)


name: RFC binding displaces Pol Alpha (Canis familiaris)


name: Loading of PCNA - Sliding Clamp Formation (Bos taurus)


name: RFC binding displaces Pol Alpha (Bos taurus)


name: RFC dissociates after sliding clamp formation (Bos taurus)


name: Formation of Processive Complex (Bos taurus)


name: RFC dissociates after sliding clamp formation (Sus scrofa)


name: RFC binding displaces Pol Alpha (Sus scrofa)


name: Formation of Processive Complex (Sus scrofa)


name: Loading of PCNA - Sliding Clamp Formation (Sus scrofa)


name: RFC binding displaces Pol Alpha (Gallus gallus)


name: RFC dissociates after sliding clamp formation (Gallus gallus)


name: Loading of PCNA - Sliding Clamp Formation (Gallus gallus)


name: Polymerase switching (Drosophila melanogaster)


name: RFC dissociates after sliding clamp formation (Drosophila melanogaster)


name: RFC binding displaces Pol Alpha (Drosophila melanogaster)


name: Loading of PCNA - Sliding Clamp Formation (Drosophila melanogaster)


name: Polymerase switching (Caenorhabditis elegans)


name: Formation of Processive Complex (Caenorhabditis elegans)


name: Loading of PCNA - Sliding Clamp Formation (Caenorhabditis elegans)


name: RFC binding displaces Pol Alpha (Caenorhabditis elegans)


name: RFC dissociates after sliding clamp formation (Caenorhabditis elegans)


name: Polymerase switching (Dictyostelium discoideum)


name: Formation of Processive Complex (Dictyostelium discoideum)


name: Loading of PCNA - Sliding Clamp Formation (Dictyostelium discoideum)


name: RFC dissociates after sliding clamp formation (Dictyostelium discoideum)


name: RFC binding displaces Pol Alpha (Dictyostelium discoideum)


name: Polymerase switching (Schizosaccharomyces pombe)


name: RFC dissociates after sliding clamp formation (Schizosaccharomyces pombe)


name: RFC binding displaces Pol Alpha (Schizosaccharomyces pombe)


name: Formation of Processive Complex (Schizosaccharomyces pombe)


name: Loading of PCNA - Sliding Clamp Formation (Schizosaccharomyces pombe)


name: Polymerase switching (Saccharomyces cerevisiae)


name: RFC dissociates after sliding clamp formation (Saccharomyces cerevisiae)


name: RFC binding displaces Pol Alpha (Saccharomyces cerevisiae)


name: Loading of PCNA - Sliding Clamp Formation (Saccharomyces cerevisiae)


name: Polymerase switching (Plasmodium falciparum)


name: Loading of PCNA - Sliding Clamp Formation (Plasmodium falciparum)


name: RFC dissociates after sliding clamp formation (Plasmodium falciparum)


name: RFC binding displaces Pol Alpha (Plasmodium falciparum)


name: Processive synthesis on the lagging strand (Homo sapiens)


name: Formation of Okazaki fragments (Homo sapiens)


name: Formation of the Flap Intermediate (Homo sapiens)


name: Joining of adjacent Okazaki fragments (Homo sapiens)


name: Removal of the Flap Intermediate (Homo sapiens)


name: Removal of RNA primer and dissociation of RPA and Dna2 (Homo sapiens)


name: Recruitment of Dna2 endonuclease (Homo sapiens)


name: Removal of remaining Flap (Homo sapiens)


name: Removal of the Flap Intermediate (Mus musculus)


name: Removal of remaining Flap (Mus musculus)


name: Recruitment of Dna2 endonuclease (Mus musculus)


name: Removal of RNA primer and dissociation of RPA and Dna2 (Mus musculus)


name: Removal of the Flap Intermediate (Rattus norvegicus)


name: Removal of remaining Flap (Rattus norvegicus)


name: Recruitment of Dna2 endonuclease (Rattus norvegicus)


name: RPA binds to the Flap (Rattus norvegicus)


name: Removal of RNA primer and dissociation of RPA and Dna2 (Rattus norvegicus)


name: Removal of the Flap Intermediate (Canis familiaris)


name: Removal of remaining Flap (Canis familiaris)


name: Recruitment of Dna2 endonuclease (Canis familiaris)


name: RPA binds to the Flap (Canis familiaris)


name: Removal of RNA primer and dissociation of RPA and Dna2 (Canis familiaris)


name: Removal of the Flap Intermediate (Bos taurus)


name: Recruitment of Dna2 endonuclease (Bos taurus)


name: Removal of RNA primer and dissociation of RPA and Dna2 (Bos taurus)


name: Removal of the Flap Intermediate (Sus scrofa)


name: Recruitment of Dna2 endonuclease (Sus scrofa)


name: Removal of RNA primer and dissociation of RPA and Dna2 (Sus scrofa)


name: Removal of the Flap Intermediate (Drosophila melanogaster)


name: Recruitment of Dna2 endonuclease (Drosophila melanogaster)


name: Removal of remaining Flap (Drosophila melanogaster)


name: RPA binds to the Flap (Drosophila melanogaster)


name: Removal of RNA primer and dissociation of RPA and Dna2 (Drosophila melanogaster)


name: Removal of the Flap Intermediate (Caenorhabditis elegans)


name: Removal of remaining Flap (Caenorhabditis elegans)


name: Recruitment of Dna2 endonuclease (Caenorhabditis elegans)


name: Removal of the Flap Intermediate (Dictyostelium discoideum)


name: Removal of remaining Flap (Dictyostelium discoideum)


name: Recruitment of Dna2 endonuclease (Dictyostelium discoideum)


name: Removal of the Flap Intermediate (Schizosaccharomyces pombe)


name: Removal of remaining Flap (Schizosaccharomyces pombe)


name: Recruitment of Dna2 endonuclease (Schizosaccharomyces pombe)


name: Removal of RNA primer and dissociation of RPA and Dna2 (Schizosaccharomyces pombe)


name: RPA binds to the Flap (Schizosaccharomyces pombe)


name: Removal of the Flap Intermediate (Saccharomyces cerevisiae)


name: Removal of remaining Flap (Saccharomyces cerevisiae)


name: Recruitment of Dna2 endonuclease (Saccharomyces cerevisiae)


name: Removal of the Flap Intermediate (Plasmodium falciparum)


name: Removal of remaining Flap (Plasmodium falciparum)


name: RPA binds to the Flap (Plasmodium falciparum)


name: Processive synthesis on the lagging strand (Mus musculus)


name: Formation of Okazaki fragments (Mus musculus)


name: Formation of the Flap Intermediate (Mus musculus)


name: Joining of adjacent Okazaki fragments (Mus musculus)


name: Processive synthesis on the lagging strand (Rattus norvegicus)


name: Formation of Okazaki fragments (Rattus norvegicus)


name: Joining of adjacent Okazaki fragments (Rattus norvegicus)


name: Formation of the Flap Intermediate (Rattus norvegicus)


name: Processive synthesis on the lagging strand (Canis familiaris)


name: Formation of Okazaki fragments (Canis familiaris)


name: Formation of the Flap Intermediate (Canis familiaris)


name: Joining of adjacent Okazaki fragments (Canis familiaris)


name: Processive synthesis on the lagging strand (Bos taurus)


name: Formation of Okazaki fragments (Bos taurus)


name: Joining of adjacent Okazaki fragments (Bos taurus)


name: Formation of the Flap Intermediate (Bos taurus)


name: Processive synthesis on the lagging strand (Sus scrofa)


name: Formation of the Flap Intermediate (Sus scrofa)


name: Joining of adjacent Okazaki fragments (Sus scrofa)


name: Formation of Okazaki fragments (Sus scrofa)


name: Processive synthesis on the lagging strand (Gallus gallus)


name: Joining of adjacent Okazaki fragments (Gallus gallus)


name: Processive synthesis on the lagging strand (Drosophila melanogaster)


name: Formation of the Flap Intermediate (Drosophila melanogaster)


name: Joining of adjacent Okazaki fragments (Drosophila melanogaster)


name: Processive synthesis on the lagging strand (Caenorhabditis elegans)


name: Formation of Okazaki fragments (Caenorhabditis elegans)


name: Joining of adjacent Okazaki fragments (Caenorhabditis elegans)


name: Formation of the Flap Intermediate (Caenorhabditis elegans)


name: Processive synthesis on the lagging strand (Dictyostelium discoideum)


name: Formation of Okazaki fragments (Dictyostelium discoideum)


name: Formation of the Flap Intermediate (Dictyostelium discoideum)


name: Joining of adjacent Okazaki fragments (Dictyostelium discoideum)


name: Processive synthesis on the lagging strand (Schizosaccharomyces pombe)


name: Formation of Okazaki fragments (Schizosaccharomyces pombe)


name: Formation of the Flap Intermediate (Schizosaccharomyces pombe)


name: Joining of adjacent Okazaki fragments (Schizosaccharomyces pombe)


name: Processive synthesis on the lagging strand (Saccharomyces cerevisiae)


name: Joining of adjacent Okazaki fragments (Saccharomyces cerevisiae)


name: Formation of the Flap Intermediate (Saccharomyces cerevisiae)


name: Processive synthesis on the lagging strand (Plasmodium falciparum)


name: Joining of adjacent Okazaki fragments (Plasmodium falciparum)


name: Formation of the Flap Intermediate (Plasmodium falciparum)


name: Formation of GINS complex (Homo sapiens)


name: MCM2-7 mediated fork unwinding (Homo sapiens)


name: Multiple proteins are localized at replication fork (Homo sapiens)


name: MCM8 mediated fork unwinding (Homo sapiens)


name: Formation of GINS complex (Mus musculus)


name: Formation of GINS complex (Rattus norvegicus)


name: Formation of GINS complex (Canis familiaris)


name: Unwinding of DNA (Drosophila melanogaster)


name: Formation of GINS complex (Drosophila melanogaster)


name: Unwinding of DNA (Caenorhabditis elegans)


name: Formation of GINS complex (Caenorhabditis elegans)


name: Unwinding of DNA (Dictyostelium discoideum)


name: Formation of GINS complex (Dictyostelium discoideum)


name: Unwinding of DNA (Schizosaccharomyces pombe)


name: Formation of GINS complex (Schizosaccharomyces pombe)


name: Unwinding of DNA (Saccharomyces cerevisiae)


name: Formation of GINS complex (Saccharomyces cerevisiae)


name: Cyclin E associated events during G1/S transition  (Homo sapiens)


name: CAK-mediated phosphorylation of Cyclin E:Cdk2 (Homo sapiens)


name: The CDC25A gene transcription is stimulated by MYC and E2F1 and inhibited by the DREAM complex (Homo sapiens)


name: Inactivation of Cyclin E:Cdk2 complexes by p27/p21 (Homo sapiens)


name: MYC:MAX binds the CDC25A gene (Homo sapiens)


name: AKT phosphorylates p21Cip1 and p27Kip1 (Homo sapiens)


name: Translocation of p21 to the nucleus (Homo sapiens)


name: Translocation of p27 to the nucleoplasm (Homo sapiens)