name: Processing of DNA double-strand break ends (Rattus norvegicus)


name: ATR activation at DNA DSBs (Rattus norvegicus)

category: biolink:MolecularActivity biolink:Occurrent biolink:OntologyClass biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent


name: BRCA1 binds phosphorylated RBBP8 (Rattus norvegicus)


name: ATM phosphorylates RBBP8 (Rattus norvegicus)


name: Activation of CHEK1 at resected DNA DSBs (Rattus norvegicus)


name: MRN complex binds CDK2 and RBBP8 (Rattus norvegicus)


name: ATR phosphorylates RPA2 (Rattus norvegicus)


name: EXO1 or DNA2 in complex with BLM or WRN binds initially resected DNA DSBs along with BRIP1 recruitment (Rattus norvegicus)


name: Long-range resection of DNA DSBs by EXO1 or DNA2 (Rattus norvegicus)


name: CDK2 phosphorylates RBBP8 (Rattus norvegicus)


name: Binding of ATR:ATRIP to RPA at resected DNA DSBs (Rattus norvegicus)


name: PIAS4 SUMOylates MDC1 (Rattus norvegicus)


name: Initial resection of double-strand break ends (Rattus norvegicus)


name: CHEK1 is recruited to resected DNA DSBs (Rattus norvegicus)


name: SIRT6 deacetylates RBBP8 (Rattus norvegicus)


name: PPP4C:PPP4R2 dephosphorylates RPA2 (Rattus norvegicus)


name: Association of RPA complexes with ssDNA at resected DNA DSBs (Rattus norvegicus)


name: Processing of DNA double-strand break ends (Canis familiaris)

category: biolink:Pathway biolink:OntologyClass biolink:BiologicalProcess biolink:Occurrent biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent


name: EXO1 or DNA2 in complex with BLM or WRN binds initially resected DNA DSBs along with BRIP1 recruitment (Canis familiaris)


name: CDK2 phosphorylates RBBP8 (Canis familiaris)


name: Association of RPA complexes with ssDNA at resected DNA DSBs (Canis familiaris)


name: Activation of CHEK1 at resected DNA DSBs (Canis familiaris)


name: Long-range resection of DNA DSBs by EXO1 or DNA2 (Canis familiaris)


name: Binding of ATR:ATRIP to RPA at resected DNA DSBs (Canis familiaris)


name: Initial resection of double-strand break ends (Canis familiaris)


name: CHEK1 is recruited to resected DNA DSBs (Canis familiaris)


name: BRCA1 binds phosphorylated RBBP8 (Canis familiaris)


name: ATR phosphorylates RPA2 (Canis familiaris)


name: PPP4C:PPP4R2 dephosphorylates RPA2 (Canis familiaris)


name: ATM phosphorylates RBBP8 (Canis familiaris)


name: ATR activation at DNA DSBs (Canis familiaris)


name: MRN complex binds CDK2 and RBBP8 (Canis familiaris)


name: SIRT6 deacetylates RBBP8 (Canis familiaris)


name: Processing of DNA double-strand break ends (Bos taurus)


name: EXO1 or DNA2 in complex with BLM or WRN binds initially resected DNA DSBs along with BRIP1 recruitment (Bos taurus)


name: MRN complex binds CDK2 and RBBP8 (Bos taurus)


name: Association of RPA complexes with ssDNA at resected DNA DSBs (Bos taurus)


name: Long-range resection of DNA DSBs by EXO1 or DNA2 (Bos taurus)


name: PPP4C:PPP4R2 dephosphorylates RPA2 (Bos taurus)


name: Initial resection of double-strand break ends (Bos taurus)


name: Binding of ATR:ATRIP to RPA at resected DNA DSBs (Bos taurus)


name: BRCA1 binds phosphorylated RBBP8 (Bos taurus)


name: Processing of DNA double-strand break ends (Sus scrofa)


name: Initial resection of double-strand break ends (Sus scrofa)


name: BRCA1 binds phosphorylated RBBP8 (Sus scrofa)


name: PPP4C:PPP4R2 dephosphorylates RPA2 (Sus scrofa)


name: MRN complex binds CDK2 and RBBP8 (Sus scrofa)


name: EXO1 or DNA2 in complex with BLM or WRN binds initially resected DNA DSBs along with BRIP1 recruitment (Sus scrofa)


name: Binding of ATR:ATRIP to RPA at resected DNA DSBs (Sus scrofa)


name: Long-range resection of DNA DSBs by EXO1 or DNA2 (Sus scrofa)


name: CHEK1 is recruited to resected DNA DSBs (Sus scrofa)


name: Activation of CHEK1 at resected DNA DSBs (Sus scrofa)


name: Association of RPA complexes with ssDNA at resected DNA DSBs (Sus scrofa)


name: Processing of DNA double-strand break ends (Danio rerio)


name: PPP4C:PPP4R2 dephosphorylates RPA2 (Danio rerio)


name: Processing of DNA double-strand break ends (Xenopus tropicalis)


name: PPP4C:PPP4R2 dephosphorylates RPA2 (Xenopus tropicalis)


name: SIRT6 deacetylates RBBP8 (Xenopus tropicalis)


name: ATR phosphorylates RPA2 (Xenopus tropicalis)


name: Processing of DNA double-strand break ends (Gallus gallus)


name: ATM phosphorylates RBBP8 (Gallus gallus)


name: Long-range resection of DNA DSBs by EXO1 or DNA2 (Gallus gallus)


name: BRCA1 binds phosphorylated RBBP8 (Gallus gallus)


name: EXO1 or DNA2 in complex with BLM or WRN binds initially resected DNA DSBs along with BRIP1 recruitment (Gallus gallus)


name: Initial resection of double-strand break ends (Gallus gallus)


name: CDK2 phosphorylates RBBP8 (Gallus gallus)


name: SIRT6 deacetylates RBBP8 (Gallus gallus)


name: Association of RPA complexes with ssDNA at resected DNA DSBs (Gallus gallus)


name: ATR activation at DNA DSBs (Gallus gallus)


name: PPP4C:PPP4R2 dephosphorylates RPA2 (Gallus gallus)


name: Binding of ATR:ATRIP to RPA at resected DNA DSBs (Gallus gallus)


name: MRN complex binds CDK2 and RBBP8 (Gallus gallus)


name: Processing of DNA double-strand break ends (Drosophila melanogaster)


name: ATM phosphorylates RBBP8 (Drosophila melanogaster)


name: PPP4C:PPP4R2 dephosphorylates RPA2 (Drosophila melanogaster)


name: CHEK1 is recruited to resected DNA DSBs (Drosophila melanogaster)


name: CDK2 phosphorylates RBBP8 (Drosophila melanogaster)


name: ATR phosphorylates RPA2 (Drosophila melanogaster)


name: Activation of CHEK1 at resected DNA DSBs (Drosophila melanogaster)


name: Processing of DNA double-strand break ends (Schizosaccharomyces pombe)


name: ATM phosphorylates RBBP8 (Schizosaccharomyces pombe)


name: CDK2 phosphorylates RBBP8 (Schizosaccharomyces pombe)


name: Presynaptic phase of homologous DNA pairing and strand exchange (Caenorhabditis elegans)


name: CHEK1 phosphorylates RAD51 (Caenorhabditis elegans)


name: Presynaptic phase of homologous DNA pairing and strand exchange (Homo sapiens)


name: RAD51 binds BRCA2 at resected DNA DSBs (Homo sapiens)


name: BRCA2 translocates to the nucleus (Homo sapiens)


name: CHEK1 phosphorylates BRCA2 (Homo sapiens)


name: BCDX2 complex stabilizes RAD51 filament (Homo sapiens)


name: CHEK1 phosphorylates RAD51 (Homo sapiens)


name: Presynaptic phase of homologous DNA pairing and strand exchange (Mus musculus)


name: BCDX2 complex stabilizes RAD51 filament (Mus musculus)


name: CHEK1 phosphorylates RAD51 (Mus musculus)


name: Presynaptic phase of homologous DNA pairing and strand exchange (Rattus norvegicus)


name: CHEK1 phosphorylates RAD51 (Rattus norvegicus)


name: BCDX2 complex stabilizes RAD51 filament (Rattus norvegicus)


name: Presynaptic phase of homologous DNA pairing and strand exchange (Canis familiaris)


name: BCDX2 complex stabilizes RAD51 filament (Canis familiaris)


name: CHEK1 phosphorylates RAD51 (Canis familiaris)


name: BCDX2 complex formation (Canis familiaris)


name: Presynaptic phase of homologous DNA pairing and strand exchange (Bos taurus)


name: BCDX2 complex stabilizes RAD51 filament (Bos taurus)


name: Presynaptic phase of homologous DNA pairing and strand exchange (Sus scrofa)


name: BCDX2 complex stabilizes RAD51 filament (Sus scrofa)


name: Presynaptic phase of homologous DNA pairing and strand exchange (Gallus gallus)


name: BCDX2 complex stabilizes RAD51 filament (Gallus gallus)


name: Presynaptic phase of homologous DNA pairing and strand exchange (Drosophila melanogaster)


name: CHEK1 phosphorylates RAD51 (Drosophila melanogaster)


name: Presynaptic phase of homologous DNA pairing and strand exchange (Schizosaccharomyces pombe)


name: CHEK1 phosphorylates RAD51 (Schizosaccharomyces pombe)


name: Presynaptic phase of homologous DNA pairing and strand exchange (Saccharomyces cerevisiae)


name: CHEK1 phosphorylates RAD51 (Saccharomyces cerevisiae)


name: Homologous DNA Pairing and Strand Exchange (Homo sapiens)


name: CX3 complex binds D-loop structures (Homo sapiens)


name: D-loop formation mediated by PALB2, BRCA2 and RAD51 (Homo sapiens)


name: Homologous DNA Pairing and Strand Exchange (Mus musculus)


name: D-loop formation mediated by PALB2, BRCA2 and RAD51 (Mus musculus)


name: CX3 complex binds D-loop structures (Mus musculus)


name: Homologous DNA Pairing and Strand Exchange (Rattus norvegicus)


name: CX3 complex binds D-loop structures (Rattus norvegicus)


name: CX3 complex formation (Rattus norvegicus)


name: D-loop formation mediated by PALB2, BRCA2 and RAD51 (Rattus norvegicus)


name: Homologous DNA Pairing and Strand Exchange (Canis familiaris)


name: CX3 complex formation (Canis familiaris)


name: D-loop formation mediated by PALB2, BRCA2 and RAD51 (Canis familiaris)


name: CX3 complex binds D-loop structures (Canis familiaris)


name: Homologous DNA Pairing and Strand Exchange (Bos taurus)


name: D-loop formation mediated by PALB2, BRCA2 and RAD51 (Bos taurus)


name: CX3 complex binds D-loop structures (Bos taurus)


name: Homologous DNA Pairing and Strand Exchange (Sus scrofa)


name: CX3 complex binds D-loop structures (Sus scrofa)


name: D-loop formation mediated by PALB2, BRCA2 and RAD51 (Sus scrofa)


name: Homologous DNA Pairing and Strand Exchange (Danio rerio)


name: Homologous DNA Pairing and Strand Exchange (Xenopus tropicalis)


name: CX3 complex formation (Xenopus tropicalis)


name: Homologous DNA Pairing and Strand Exchange (Gallus gallus)


name: CX3 complex binds D-loop structures (Gallus gallus)


name: D-loop formation mediated by PALB2, BRCA2 and RAD51 (Gallus gallus)


name: Homologous DNA Pairing and Strand Exchange (Plasmodium falciparum)


name: CX3 complex formation (Plasmodium falciparum)


name: HDR through Homologous Recombination (HRR) (Homo sapiens)


name: D-loop extension by DNA polymerases (Homo sapiens)


name: Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) (Homo sapiens)


DNA helicase activity

description: Unwinding of a DNA helix, driven by ATP hydrolysis.


name: Gap-filling DNA synthesis in SDSA (Homo sapiens)


name: Resolution of D-loop Structures through Holliday Junction Intermediates (Homo sapiens)


name: MUS81:EME1,EME2 cleaves D-loop (Homo sapiens)


name: SLX1A:SLX4 binds MUS81:EME1,(MUS81:EME2) (Homo sapiens)


name: BLM mediates dissolution of double Holliday junction (Homo sapiens)


name: SPIDR binds BLM:TOP3A:RMI1:RMI2 (Homo sapiens)


name: Cleavage of Holliday junctions by GEN1 or SLX1A:SLX4:MUS81:EME1,(MUS81:EME2) (Homo sapiens)


name: Resolution of Holliday junctions cleaved by GEN1 or SLX1A:SLX4:MUS81:EME1,(MUS81:EME2) (Homo sapiens)


name: Ligation of DNA and formation of Holliday structures following repair synthesis (Homo sapiens)


name: Resolution of D-loops cleaved by MUS81:EME1 or MUS81:EME2 (Homo sapiens)


name: Resolution of D-loop Structures through Holliday Junction Intermediates (Mus musculus)


name: Cleavage of Holliday junctions by GEN1 or SLX1A:SLX4:MUS81:EME1,(MUS81:EME2) (Mus musculus)


name: SPIDR binds BLM:TOP3A:RMI1:RMI2 (Mus musculus)


name: Ligation of DNA and formation of Holliday structures following repair synthesis (Mus musculus)


name: MUS81:EME1,EME2 cleaves D-loop (Mus musculus)


name: SLX1A:SLX4 binds MUS81:EME1,(MUS81:EME2) (Mus musculus)


name: Resolution of D-loop Structures through Holliday Junction Intermediates (Rattus norvegicus)


name: SPIDR binds BLM:TOP3A:RMI1:RMI2 (Rattus norvegicus)


name: Ligation of DNA and formation of Holliday structures following repair synthesis (Rattus norvegicus)


name: MUS81 binds EME1, EME2 (Rattus norvegicus)


name: SLX1A:SLX4 binds MUS81:EME1,(MUS81:EME2) (Rattus norvegicus)


name: Cleavage of Holliday junctions by GEN1 or SLX1A:SLX4:MUS81:EME1,(MUS81:EME2) (Rattus norvegicus)


name: MUS81:EME1,EME2 cleaves D-loop (Rattus norvegicus)


name: Resolution of D-loop Structures through Holliday Junction Intermediates (Canis familiaris)


name: SLX1A:SLX4 binds MUS81:EME1,(MUS81:EME2) (Canis familiaris)


name: MUS81 binds EME1, EME2 (Canis familiaris)


name: MUS81:EME1,EME2 cleaves D-loop (Canis familiaris)


name: Cleavage of Holliday junctions by GEN1 or SLX1A:SLX4:MUS81:EME1,(MUS81:EME2) (Canis familiaris)


name: Ligation of DNA and formation of Holliday structures following repair synthesis (Canis familiaris)


name: Resolution of D-loop Structures through Holliday Junction Intermediates (Bos taurus)


name: MUS81:EME1,EME2 cleaves D-loop (Bos taurus)


name: SLX1A:SLX4 binds MUS81:EME1,(MUS81:EME2) (Bos taurus)


name: Cleavage of Holliday junctions by GEN1 or SLX1A:SLX4:MUS81:EME1,(MUS81:EME2) (Bos taurus)


name: SPIDR binds BLM:TOP3A:RMI1:RMI2 (Bos taurus)


name: Ligation of DNA and formation of Holliday structures following repair synthesis (Bos taurus)


name: Resolution of D-loop Structures through Holliday Junction Intermediates (Sus scrofa)


name: Cleavage of Holliday junctions by GEN1 or SLX1A:SLX4:MUS81:EME1,(MUS81:EME2) (Sus scrofa)


name: SLX1A:SLX4 binds MUS81:EME1,(MUS81:EME2) (Sus scrofa)


name: MUS81:EME1,EME2 cleaves D-loop (Sus scrofa)


name: Ligation of DNA and formation of Holliday structures following repair synthesis (Sus scrofa)


name: SPIDR binds BLM:TOP3A:RMI1:RMI2 (Sus scrofa)


name: Resolution of D-loop Structures through Holliday Junction Intermediates (Danio rerio)


name: Resolution of D-loop Structures through Holliday Junction Intermediates (Xenopus tropicalis)


name: SPIDR binds BLM:TOP3A:RMI1:RMI2 (Xenopus tropicalis)


name: MUS81 binds EME1, EME2 (Xenopus tropicalis)


name: SLX1A:SLX4 binds MUS81:EME1,(MUS81:EME2) (Xenopus tropicalis)


name: Resolution of D-loop Structures through Holliday Junction Intermediates (Gallus gallus)


name: Cleavage of Holliday junctions by GEN1 or SLX1A:SLX4:MUS81:EME1,(MUS81:EME2) (Gallus gallus)


name: Ligation of DNA and formation of Holliday structures following repair synthesis (Gallus gallus)


name: SPIDR binds BLM:TOP3A:RMI1:RMI2 (Gallus gallus)


name: Resolution of D-loop Structures through Holliday Junction Intermediates (Schizosaccharomyces pombe)


name: MUS81 binds EME1, EME2 (Schizosaccharomyces pombe)


name: Resolution of D-loop Structures through Holliday Junction Intermediates (Saccharomyces cerevisiae)


name: MUS81 binds EME1, EME2 (Saccharomyces cerevisiae)


name: HDR through Homologous Recombination (HRR) (Mus musculus)


name: D-loop extension by DNA polymerases (Mus musculus)


name: HDR through Homologous Recombination (HRR) (Rattus norvegicus)


name: D-loop extension by DNA polymerases (Rattus norvegicus)


name: HDR through Homologous Recombination (HRR) (Canis familiaris)


name: D-loop extension by DNA polymerases (Canis familiaris)


name: HDR through Homologous Recombination (HRR) (Bos taurus)


name: D-loop extension by DNA polymerases (Bos taurus)


name: HDR through Homologous Recombination (HRR) (Sus scrofa)


name: D-loop extension by DNA polymerases (Sus scrofa)


name: HDR through Homologous Recombination (HRR) (Gallus gallus)


name: D-loop extension by DNA polymerases (Gallus gallus)


name: HDR through Single Strand Annealing (SSA) (Homo sapiens)


name: Formation of RAD52 heptameric ring structure complexes (Homo sapiens)


name: ABL1 phosphorylates RAD52 (Homo sapiens)


name: Association of RAD51 with RAD52:DNA double-strand break ends (Homo sapiens)


name: Association of RAD52 with the RPA complex at resected DNA DSBs (Homo sapiens)


name: ERCC1:XPF cleaves flaps generated by SSA (Homo sapiens)


annealing activity

description: An activity that facilitates the formation of a complementary double-stranded polynucleotide molecule.


name: HDR through Single Strand Annealing (SSA) (Mus musculus)


name: Formation of RAD52 heptameric ring structure complexes (Mus musculus)


name: ERCC1:XPF cleaves flaps generated by SSA (Mus musculus)


name: Association of RAD51 with RAD52:DNA double-strand break ends (Mus musculus)


name: Association of RAD52 with the RPA complex at resected DNA DSBs (Mus musculus)


name: ABL1 phosphorylates RAD52 (Mus musculus)


name: RAD52 promotes single strand annealing at resected DNA DSBs (Mus musculus)


name: HDR through Single Strand Annealing (SSA) (Rattus norvegicus)


name: Association of RAD51 with RAD52:DNA double-strand break ends (Rattus norvegicus)


name: ERCC1:XPF cleaves flaps generated by SSA (Rattus norvegicus)


name: RAD52 promotes single strand annealing at resected DNA DSBs (Rattus norvegicus)


name: Association of RAD52 with the RPA complex at resected DNA DSBs (Rattus norvegicus)


name: ABL1 phosphorylates RAD52 (Rattus norvegicus)


name: Formation of RAD52 heptameric ring structure complexes (Rattus norvegicus)


name: HDR through Single Strand Annealing (SSA) (Canis familiaris)


name: Formation of RAD52 heptameric ring structure complexes (Canis familiaris)


name: Association of RAD51 with RAD52:DNA double-strand break ends (Canis familiaris)


name: Association of RAD52 with the RPA complex at resected DNA DSBs (Canis familiaris)


name: RAD52 promotes single strand annealing at resected DNA DSBs (Canis familiaris)


name: ABL1 phosphorylates RAD52 (Canis familiaris)


name: ERCC1:XPF cleaves flaps generated by SSA (Canis familiaris)


name: HDR through Single Strand Annealing (SSA) (Bos taurus)


name: RAD52 promotes single strand annealing at resected DNA DSBs (Bos taurus)


name: Association of RAD51 with RAD52:DNA double-strand break ends (Bos taurus)


name: Formation of RAD52 heptameric ring structure complexes (Bos taurus)


name: ERCC1:XPF cleaves flaps generated by SSA (Bos taurus)


name: Association of RAD52 with the RPA complex at resected DNA DSBs (Bos taurus)


name: HDR through Single Strand Annealing (SSA) (Sus scrofa)


name: Association of RAD52 with the RPA complex at resected DNA DSBs (Sus scrofa)


name: RAD52 promotes single strand annealing at resected DNA DSBs (Sus scrofa)


name: Formation of RAD52 heptameric ring structure complexes (Sus scrofa)


name: ERCC1:XPF cleaves flaps generated by SSA (Sus scrofa)


name: Association of RAD51 with RAD52:DNA double-strand break ends (Sus scrofa)


name: HDR through Single Strand Annealing (SSA) (Xenopus tropicalis)


name: RAD52 promotes single strand annealing at resected DNA DSBs (Xenopus tropicalis)


name: Association of RAD52 with the RPA complex at resected DNA DSBs (Xenopus tropicalis)


name: ABL1 phosphorylates RAD52 (Xenopus tropicalis)


name: Association of RAD51 with RAD52:DNA double-strand break ends (Xenopus tropicalis)


name: Formation of RAD52 heptameric ring structure complexes (Xenopus tropicalis)


name: HDR through Single Strand Annealing (SSA) (Gallus gallus)


name: RAD52 promotes single strand annealing at resected DNA DSBs (Gallus gallus)


name: Formation of RAD52 heptameric ring structure complexes (Gallus gallus)


name: Association of RAD51 with RAD52:DNA double-strand break ends (Gallus gallus)


name: Association of RAD52 with the RPA complex at resected DNA DSBs (Gallus gallus)


name: ABL1 phosphorylates RAD52 (Gallus gallus)


name: HDR through Single Strand Annealing (SSA) (Dictyostelium discoideum)


name: Formation of RAD52 heptameric ring structure complexes (Dictyostelium discoideum)


name: HDR through Single Strand Annealing (SSA) (Schizosaccharomyces pombe)


name: Formation of RAD52 heptameric ring structure complexes (Schizosaccharomyces pombe)


name: HDR through Single Strand Annealing (SSA) (Saccharomyces cerevisiae)


name: Formation of RAD52 heptameric ring structure complexes (Saccharomyces cerevisiae)


name: HDR through MMEJ (alt-NHEJ) (Homo sapiens)


name: MRN recruits LIG3:XRCC1 to MMEJ sites (Homo sapiens)


name: POLQ extends annealed 3'-ssDNA overhangs in MMEJ (Homo sapiens)


name: MRN and RBBP8 resect DNA DSBs in MMEJ (Homo sapiens)


name: LIG3 ligates remaining SSBs in MMEJ (Homo sapiens)


name: PARP1 or PARP2, FEN1 and POLQ are recruited to MMEJ site (Homo sapiens)


name: FEN1 cleaves displaced ssDNA flaps during MMEJ (Homo sapiens)


name: PARP1,PARP2 dimers bound to MMEJ sites autoPARylate (Homo sapiens)


name: HDR through MMEJ (alt-NHEJ) (Mus musculus)


name: PARP1,PARP2 dimers bound to MMEJ sites autoPARylate (Mus musculus)


name: LIG3 ligates remaining SSBs in MMEJ (Mus musculus)


name: PARP1 or PARP2, FEN1 and POLQ are recruited to MMEJ site (Mus musculus)


name: MRN and RBBP8 resect DNA DSBs in MMEJ (Mus musculus)


name: MRN recruits LIG3:XRCC1 to MMEJ sites (Mus musculus)


name: POLQ extends annealed 3'-ssDNA overhangs in MMEJ (Mus musculus)


name: FEN1 cleaves displaced ssDNA flaps during MMEJ (Mus musculus)


name: Nonhomologous End-Joining (NHEJ) (Mus musculus)


name: TP53BP1 recruits DCLRE1C to ATM (Mus musculus)


name: Association of Ku heterodimer with ends of DNA double-strand break (Mus musculus)


name: Activated ATM phosphorylates DCLRE1C (Mus musculus)


name: XRCC4:LIG4, NHEJ1 and POLL or POLM bind DNA DSBs in NHEJ (Mus musculus)


name: DCLRE1C (ARTEMIS) processes DNA DSB ends (Mus musculus)


name: PRKDC phosphorylates DCLRE1C at DNA DSBs (Mus musculus)


name: Association of DNA-PKcs with Ku-bound ends of DNA double-strand breaks - synapsis (Mus musculus)


name: DCLRE1C binds PRKDC:XRCC5:XRCC6 at DNA DSBs (Mus musculus)


name: DNA-PKcs autophosphorylates (Mus musculus)


name: POLL or POLM extends aligned DNA DSB ends to fill gaps (Mus musculus)


name: TDP1 and TDP2 process unligatable DSB ends (Mus musculus)


name: RIF1 and PAX1IP bind TP53BP1 at DNA DSBs (Mus musculus)


name: Nonhomologous End-Joining (NHEJ) (Homo sapiens)


name: TP53BP1 recruits DCLRE1C to ATM (Homo sapiens)


name: Activated ATM phosphorylates DCLRE1C (Homo sapiens)


name: Association of Ku heterodimer with ends of DNA double-strand break (Homo sapiens)


name: RIF1 and PAX1IP bind TP53BP1 at DNA DSBs (Homo sapiens)


name: DCLRE1C (ARTEMIS) processes DNA DSB ends (Homo sapiens)


name: XRCC4:LIG4, NHEJ1 and POLL or POLM bind DNA DSBs in NHEJ (Homo sapiens)


name: DNA-PKcs autophosphorylates (Homo sapiens)


name: XRCC4:LIG4 ligates DNA DSB ends during NHEJ (Homo sapiens)


name: POLL or POLM extends aligned DNA DSB ends to fill gaps (Homo sapiens)


name: Association of DNA-PKcs with Ku-bound ends of DNA double-strand breaks - synapsis (Homo sapiens)


name: PRKDC phosphorylates DCLRE1C at DNA DSBs (Homo sapiens)


name: DCLRE1C binds PRKDC:XRCC5:XRCC6 at DNA DSBs (Homo sapiens)


name: TDP1 and TDP2 process unligatable DSB ends (Homo sapiens)


name: Nonhomologous End-Joining (NHEJ) (Rattus norvegicus)


name: POLL or POLM extends aligned DNA DSB ends to fill gaps (Rattus norvegicus)


name: Association of DNA-PKcs with Ku-bound ends of DNA double-strand breaks - synapsis (Rattus norvegicus)


name: TDP1 and TDP2 process unligatable DSB ends (Rattus norvegicus)


name: TP53BP1 recruits DCLRE1C to ATM (Rattus norvegicus)


name: PRKDC phosphorylates DCLRE1C at DNA DSBs (Rattus norvegicus)


name: DNA-PKcs autophosphorylates (Rattus norvegicus)


name: RIF1 and PAX1IP bind TP53BP1 at DNA DSBs (Rattus norvegicus)


name: Activated ATM phosphorylates DCLRE1C (Rattus norvegicus)


name: XRCC4:LIG4, NHEJ1 and POLL or POLM bind DNA DSBs in NHEJ (Rattus norvegicus)


name: DCLRE1C (ARTEMIS) processes DNA DSB ends (Rattus norvegicus)


name: DCLRE1C binds PRKDC:XRCC5:XRCC6 at DNA DSBs (Rattus norvegicus)


name: HDR through MMEJ (alt-NHEJ) (Rattus norvegicus)


name: FEN1 cleaves displaced ssDNA flaps during MMEJ (Rattus norvegicus)


name: LIG3 ligates remaining SSBs in MMEJ (Rattus norvegicus)


name: PARP1 or PARP2, FEN1 and POLQ are recruited to MMEJ site (Rattus norvegicus)


name: MRN and RBBP8 resect DNA DSBs in MMEJ (Rattus norvegicus)


name: PARP1,PARP2 dimers bound to MMEJ sites autoPARylate (Rattus norvegicus)


name: MRN complex binds RBBP8 (Rattus norvegicus)


name: POLQ extends annealed 3'-ssDNA overhangs in MMEJ (Rattus norvegicus)


name: MRN recruits LIG3:XRCC1 to MMEJ sites (Rattus norvegicus)


name: Nonhomologous End-Joining (NHEJ) (Canis familiaris)


name: TP53BP1 recruits DCLRE1C to ATM (Canis familiaris)


name: XRCC4:LIG4, NHEJ1 and POLL or POLM bind DNA DSBs in NHEJ (Canis familiaris)


name: RIF1 and PAX1IP bind TP53BP1 at DNA DSBs (Canis familiaris)


name: Association of DNA-PKcs with Ku-bound ends of DNA double-strand breaks - synapsis (Canis familiaris)


name: DCLRE1C (ARTEMIS) processes DNA DSB ends (Canis familiaris)


name: PRKDC phosphorylates DCLRE1C at DNA DSBs (Canis familiaris)


name: Activated ATM phosphorylates DCLRE1C (Canis familiaris)


name: TDP1 and TDP2 process unligatable DSB ends (Canis familiaris)


name: DCLRE1C binds PRKDC:XRCC5:XRCC6 at DNA DSBs (Canis familiaris)


name: DNA-PKcs autophosphorylates (Canis familiaris)


name: POLL or POLM extends aligned DNA DSB ends to fill gaps (Canis familiaris)


name: HDR through MMEJ (alt-NHEJ) (Canis familiaris)


name: MRN and RBBP8 resect DNA DSBs in MMEJ (Canis familiaris)


name: MRN complex binds RBBP8 (Canis familiaris)


name: MRN recruits LIG3:XRCC1 to MMEJ sites (Canis familiaris)


name: FEN1 cleaves displaced ssDNA flaps during MMEJ (Canis familiaris)


name: POLQ extends annealed 3'-ssDNA overhangs in MMEJ (Canis familiaris)


name: LIG3 ligates remaining SSBs in MMEJ (Canis familiaris)


name: Nonhomologous End-Joining (NHEJ) (Bos taurus)


name: RIF1 and PAX1IP bind TP53BP1 at DNA DSBs (Bos taurus)


name: TP53BP1 recruits DCLRE1C to ATM (Bos taurus)


name: XRCC4:LIG4, NHEJ1 and POLL or POLM bind DNA DSBs in NHEJ (Bos taurus)


name: DCLRE1C (ARTEMIS) processes DNA DSB ends (Bos taurus)


name: Association of DNA-PKcs with Ku-bound ends of DNA double-strand breaks - synapsis (Bos taurus)


name: POLL or POLM extends aligned DNA DSB ends to fill gaps (Bos taurus)


name: PRKDC phosphorylates DCLRE1C at DNA DSBs (Bos taurus)


name: DCLRE1C binds PRKDC:XRCC5:XRCC6 at DNA DSBs (Bos taurus)


name: Association of Ku heterodimer with ends of DNA double-strand break (Bos taurus)


name: Activated ATM phosphorylates DCLRE1C (Bos taurus)


name: DNA-PKcs autophosphorylates (Bos taurus)


name: TDP1 and TDP2 process unligatable DSB ends (Bos taurus)


name: HDR through MMEJ (alt-NHEJ) (Bos taurus)


name: PARP1,PARP2 dimers bound to MMEJ sites autoPARylate (Bos taurus)


name: FEN1 cleaves displaced ssDNA flaps during MMEJ (Bos taurus)


name: MRN recruits LIG3:XRCC1 to MMEJ sites (Bos taurus)


name: POLQ extends annealed 3'-ssDNA overhangs in MMEJ (Bos taurus)


name: LIG3 ligates remaining SSBs in MMEJ (Bos taurus)


name: PARP1 or PARP2, FEN1 and POLQ are recruited to MMEJ site (Bos taurus)


name: MRN and RBBP8 resect DNA DSBs in MMEJ (Bos taurus)


name: Nonhomologous End-Joining (NHEJ) (Sus scrofa)


name: Activated ATM phosphorylates DCLRE1C (Sus scrofa)


name: POLL or POLM extends aligned DNA DSB ends to fill gaps (Sus scrofa)


name: TDP1 and TDP2 process unligatable DSB ends (Sus scrofa)


name: TP53BP1 recruits DCLRE1C to ATM (Sus scrofa)


name: DNA-PKcs autophosphorylates (Sus scrofa)


name: RIF1 and PAX1IP bind TP53BP1 at DNA DSBs (Sus scrofa)


name: Association of DNA-PKcs with Ku-bound ends of DNA double-strand breaks - synapsis (Sus scrofa)


name: PRKDC phosphorylates DCLRE1C at DNA DSBs (Sus scrofa)


name: DCLRE1C (ARTEMIS) processes DNA DSB ends (Sus scrofa)


name: DCLRE1C binds PRKDC:XRCC5:XRCC6 at DNA DSBs (Sus scrofa)


name: HDR through MMEJ (alt-NHEJ) (Sus scrofa)


name: FEN1 cleaves displaced ssDNA flaps during MMEJ (Sus scrofa)


name: POLQ extends annealed 3'-ssDNA overhangs in MMEJ (Sus scrofa)


name: MRN recruits LIG3:XRCC1 to MMEJ sites (Sus scrofa)


name: LIG3 ligates remaining SSBs in MMEJ (Sus scrofa)


name: PARP1 or PARP2, FEN1 and POLQ are recruited to MMEJ site (Sus scrofa)


name: MRN and RBBP8 resect DNA DSBs in MMEJ (Sus scrofa)


name: PARP1,PARP2 dimers bound to MMEJ sites autoPARylate (Sus scrofa)


name: Nonhomologous End-Joining (NHEJ) (Xenopus tropicalis)


name: POLL or POLM extends aligned DNA DSB ends to fill gaps (Xenopus tropicalis)


name: Nonhomologous End-Joining (NHEJ) (Gallus gallus)


name: DCLRE1C (ARTEMIS) processes DNA DSB ends (Gallus gallus)


name: POLL or POLM extends aligned DNA DSB ends to fill gaps (Gallus gallus)


name: XRCC4:LIG4, NHEJ1 and POLL or POLM bind DNA DSBs in NHEJ (Gallus gallus)


name: PRKDC phosphorylates DCLRE1C at DNA DSBs (Gallus gallus)


name: RIF1 and PAX1IP bind TP53BP1 at DNA DSBs (Gallus gallus)


name: Activated ATM phosphorylates DCLRE1C (Gallus gallus)


name: TDP1 and TDP2 process unligatable DSB ends (Gallus gallus)


name: Association of DNA-PKcs with Ku-bound ends of DNA double-strand breaks - synapsis (Gallus gallus)


name: DNA-PKcs autophosphorylates (Gallus gallus)


name: TP53BP1 recruits DCLRE1C to ATM (Gallus gallus)


name: DCLRE1C binds PRKDC:XRCC5:XRCC6 at DNA DSBs (Gallus gallus)


name: HDR through MMEJ (alt-NHEJ) (Gallus gallus)


name: LIG3 ligates remaining SSBs in MMEJ (Gallus gallus)


name: PARP1 or PARP2, FEN1 and POLQ are recruited to MMEJ site (Gallus gallus)


name: MRN and RBBP8 resect DNA DSBs in MMEJ (Gallus gallus)


name: PARP1,PARP2 dimers bound to MMEJ sites autoPARylate (Gallus gallus)


name: MRN recruits LIG3:XRCC1 to MMEJ sites (Gallus gallus)


name: FEN1 cleaves displaced ssDNA flaps during MMEJ (Gallus gallus)


name: POLQ extends annealed 3'-ssDNA overhangs in MMEJ (Gallus gallus)


name: Nonhomologous End-Joining (NHEJ) (Dictyostelium discoideum)


name: DCLRE1C (ARTEMIS) processes DNA DSB ends (Dictyostelium discoideum)


name: DNA-PKcs autophosphorylates (Dictyostelium discoideum)


name: TDP1 and TDP2 process unligatable DSB ends (Dictyostelium discoideum)


name: PRKDC phosphorylates DCLRE1C at DNA DSBs (Dictyostelium discoideum)


name: POLL or POLM extends aligned DNA DSB ends to fill gaps (Dictyostelium discoideum)


name: Association of DNA-PKcs with Ku-bound ends of DNA double-strand breaks - synapsis (Dictyostelium discoideum)


name: HDR through MMEJ (alt-NHEJ) (Drosophila melanogaster)


name: MRN recruits LIG3:XRCC1 to MMEJ sites (Drosophila melanogaster)


name: POLQ extends annealed 3'-ssDNA overhangs in MMEJ (Drosophila melanogaster)


name: PARP1,PARP2 dimers bound to MMEJ sites autoPARylate (Drosophila melanogaster)


name: MRN and RBBP8 resect DNA DSBs in MMEJ (Drosophila melanogaster)


name: PARP1 or PARP2, FEN1 and POLQ are recruited to MMEJ site (Drosophila melanogaster)


name: FEN1 cleaves displaced ssDNA flaps during MMEJ (Drosophila melanogaster)


name: HDR through MMEJ (alt-NHEJ) (Caenorhabditis elegans)


name: MRN and RBBP8 resect DNA DSBs in MMEJ (Caenorhabditis elegans)


name: FEN1 cleaves displaced ssDNA flaps during MMEJ (Caenorhabditis elegans)


name: HDR through MMEJ (alt-NHEJ) (Schizosaccharomyces pombe)


name: MRN and RBBP8 resect DNA DSBs in MMEJ (Schizosaccharomyces pombe)


name: FEN1 cleaves displaced ssDNA flaps during MMEJ (Schizosaccharomyces pombe)


name: Oxidative Stress Induced Senescence (Caenorhabditis elegans)


name: KDM6B demethylates H3K27me3 on p16INK4A promoter (Caenorhabditis elegans)


name: KDM6B binds iron (Caenorhabditis elegans)


name: ROS oxidize thioredoxin and activate MAP3K5 (Caenorhabditis elegans)


name: PRC2-EZH2 trimethylates nucleosomes associated with CDKN2A promoter (Caenorhabditis elegans)


name: MAP3K5 phosphorylates MKK3 and MKK6 (Caenorhabditis elegans)


name: DNA Damage/Telomere Stress Induced Senescence (Caenorhabditis elegans)


name: Formation of Senescence-Associated Heterochromatin Foci (SAHF) (Caenorhabditis elegans)


name: Formation of Senescence-Associated Heterochromatin Foci (SAHF) (Homo sapiens)


name: Initiation of SAHF formation (Homo sapiens)


name: Formation of Senescence-Associated Heterochromatin Foci (SAHF) (Mus musculus)


name: Initiation of SAHF formation (Mus musculus)


name: Formation of Senescence-Associated Heterochromatin Foci (SAHF) (Rattus norvegicus)


name: Initiation of SAHF formation (Rattus norvegicus)


name: Formation of Senescence-Associated Heterochromatin Foci (SAHF) (Canis familiaris)


name: Initiation of SAHF formation (Canis familiaris)


name: Formation of Senescence-Associated Heterochromatin Foci (SAHF) (Bos taurus)


name: Initiation of SAHF formation (Bos taurus)


name: Formation of Senescence-Associated Heterochromatin Foci (SAHF) (Sus scrofa)


name: Initiation of SAHF formation (Sus scrofa)


name: Formation of Senescence-Associated Heterochromatin Foci (SAHF) (Gallus gallus)


name: Initiation of SAHF formation (Gallus gallus)


name: Formation of Senescence-Associated Heterochromatin Foci (SAHF) (Saccharomyces cerevisiae)


name: Initiation of SAHF formation (Saccharomyces cerevisiae)


name: Senescence-Associated Secretory Phenotype (SASP) (Caenorhabditis elegans)


name: Transcriptional Regulation by VENTX (Caenorhabditis elegans)


name: VENTX disrupts binding of CTNNB1 (beta-catenin) to TCF4 or LEF1 (Caenorhabditis elegans)


name: TCF dependent signaling in response to WNT (Caenorhabditis elegans)


name: Beta-catenin translocates to the nucleus (Caenorhabditis elegans)


name: WNT mediated activation of DVL (Caenorhabditis elegans)


name: WNT signaling stimulates CSNK1-dependent phosphorylation of DVL (Caenorhabditis elegans)


name: DVL-associated PIP5K1B phosphorylates PI4P to PI(4,5)P2 (Caenorhabditis elegans)


name: CSNK2-mediated phosphorylation of DVL (Caenorhabditis elegans)


name: Phosphorylated DVL recruits PIP5K1B to the plasma membrane (Caenorhabditis elegans)


name: WNT mediated activation of DVL (Homo sapiens)


name: DVL-associated PIP5K1B phosphorylates PI4P to PI(4,5)P2 (Homo sapiens)


name: Phosphorylated DVL recruits PIP5K1B to the plasma membrane (Homo sapiens)


name: WNT signaling stimulates CSNK1-dependent phosphorylation of DVL (Homo sapiens)


name: CSNK2-mediated phosphorylation of DVL (Homo sapiens)


name: WNT mediated activation of DVL (Mus musculus)


name: WNT signaling stimulates CSNK1-dependent phosphorylation of DVL (Mus musculus)


name: Phosphorylated DVL recruits PIP5K1B to the plasma membrane (Mus musculus)


name: CSNK2-mediated phosphorylation of DVL (Mus musculus)


name: DVL-associated PIP5K1B phosphorylates PI4P to PI(4,5)P2 (Mus musculus)


name: WNT mediated activation of DVL (Rattus norvegicus)


name: Phosphorylated DVL recruits PIP5K1B to the plasma membrane (Rattus norvegicus)


name: CSNK2-mediated phosphorylation of DVL (Rattus norvegicus)


name: WNT signaling stimulates CSNK1-dependent phosphorylation of DVL (Rattus norvegicus)


name: DVL-associated PIP5K1B phosphorylates PI4P to PI(4,5)P2 (Rattus norvegicus)


name: WNT mediated activation of DVL (Canis familiaris)


name: Phosphorylated DVL recruits PIP5K1B to the plasma membrane (Canis familiaris)


name: CSNK2-mediated phosphorylation of DVL (Canis familiaris)


name: DVL-associated PIP5K1B phosphorylates PI4P to PI(4,5)P2 (Canis familiaris)


name: WNT mediated activation of DVL (Bos taurus)


name: Phosphorylated DVL recruits PIP5K1B to the plasma membrane (Bos taurus)


name: DVL-associated PIP5K1B phosphorylates PI4P to PI(4,5)P2 (Bos taurus)


name: WNT signaling stimulates CSNK1-dependent phosphorylation of DVL (Bos taurus)


name: CSNK2-mediated phosphorylation of DVL (Bos taurus)


name: WNT mediated activation of DVL (Sus scrofa)


name: WNT signaling stimulates CSNK1-dependent phosphorylation of DVL (Sus scrofa)


name: DVL-associated PIP5K1B phosphorylates PI4P to PI(4,5)P2 (Sus scrofa)


name: Phosphorylated DVL recruits PIP5K1B to the plasma membrane (Sus scrofa)


name: CSNK2-mediated phosphorylation of DVL (Sus scrofa)


name: WNT mediated activation of DVL (Danio rerio)


name: WNT signaling stimulates CSNK1-dependent phosphorylation of DVL (Danio rerio)


name: WNT mediated activation of DVL (Xenopus tropicalis)


name: WNT signaling stimulates CSNK1-dependent phosphorylation of DVL (Xenopus tropicalis)


name: WNT mediated activation of DVL (Gallus gallus)


name: DVL-associated PIP5K1B phosphorylates PI4P to PI(4,5)P2 (Gallus gallus)


name: Phosphorylated DVL recruits PIP5K1B to the plasma membrane (Gallus gallus)


name: WNT signaling stimulates CSNK1-dependent phosphorylation of DVL (Gallus gallus)


name: WNT mediated activation of DVL (Drosophila melanogaster)


name: DVL-associated PIP5K1B phosphorylates PI4P to PI(4,5)P2 (Drosophila melanogaster)


name: CSNK2-mediated phosphorylation of DVL (Drosophila melanogaster)


name: WNT signaling stimulates CSNK1-dependent phosphorylation of DVL (Drosophila melanogaster)


name: Phosphorylated DVL recruits PIP5K1B to the plasma membrane (Drosophila melanogaster)


name: Disassembly of the destruction complex and recruitment of AXIN to the membrane (Caenorhabditis elegans)


name: Phosphorylation of LRP5/6 cytoplasmic domain by membrane-associated GSK3beta (Caenorhabditis elegans)


name: DVL recruits GSK3beta:AXIN1 to the receptor complex (Caenorhabditis elegans)


name: WNT3A stimulates the caveolin-dependent internalization of FZD5:p-LRP6 (Caenorhabditis elegans)


name: Disassembly of the destruction complex and recruitment of AXIN to the membrane (Homo sapiens)


name: WNT3A stimulates the caveolin-dependent internalization of FZD5:p-LRP6 (Homo sapiens)


name: Beta-catenin is released from the destruction complex (Homo sapiens)


name: FRAT proteins bind GSK3beta (Homo sapiens)


name: PP2A dephosphorylates AXIN, APC and CTNNB1 in the destruction complex (Homo sapiens)


name: Phosphorylation of LRP5/6 cytoplasmic domain by CSNKI (Homo sapiens)


name: DVL recruits GSK3beta:AXIN1 to the receptor complex (Homo sapiens)


name: Phosphorylation of LRP5/6 cytoplasmic domain by membrane-associated GSK3beta (Homo sapiens)


name: Disassembly of the destruction complex and recruitment of AXIN to the membrane (Mus musculus)


name: WNT3A stimulates the caveolin-dependent internalization of FZD5:p-LRP6 (Mus musculus)


name: Beta-catenin is released from the destruction complex (Mus musculus)


name: Phosphorylation of LRP5/6 cytoplasmic domain by membrane-associated GSK3beta (Mus musculus)


name: FRAT proteins bind GSK3beta (Mus musculus)


name: DVL recruits GSK3beta:AXIN1 to the receptor complex (Mus musculus)


name: Disassembly of the destruction complex and recruitment of AXIN to the membrane (Rattus norvegicus)


name: DVL recruits GSK3beta:AXIN1 to the receptor complex (Rattus norvegicus)


name: WNT3A stimulates the caveolin-dependent internalization of FZD5:p-LRP6 (Rattus norvegicus)


name: Phosphorylation of LRP5/6 cytoplasmic domain by membrane-associated GSK3beta (Rattus norvegicus)


name: Beta-catenin is released from the destruction complex (Rattus norvegicus)


name: FRAT proteins bind GSK3beta (Rattus norvegicus)


name: Disassembly of the destruction complex and recruitment of AXIN to the membrane (Canis familiaris)


name: Phosphorylation of LRP5/6 cytoplasmic domain by membrane-associated GSK3beta (Canis familiaris)


name: DVL recruits GSK3beta:AXIN1 to the receptor complex (Canis familiaris)


name: Beta-catenin is released from the destruction complex (Canis familiaris)


name: FRAT proteins bind GSK3beta (Canis familiaris)


name: WNT3A stimulates the caveolin-dependent internalization of FZD5:p-LRP6 (Canis familiaris)


name: Disassembly of the destruction complex and recruitment of AXIN to the membrane (Bos taurus)


name: FRAT proteins bind GSK3beta (Bos taurus)


name: DVL recruits GSK3beta:AXIN1 to the receptor complex (Bos taurus)


name: Beta-catenin is released from the destruction complex (Bos taurus)


name: WNT3A stimulates the caveolin-dependent internalization of FZD5:p-LRP6 (Bos taurus)


name: Phosphorylation of LRP5/6 cytoplasmic domain by membrane-associated GSK3beta (Bos taurus)


name: Disassembly of the destruction complex and recruitment of AXIN to the membrane (Sus scrofa)


name: Phosphorylation of LRP5/6 cytoplasmic domain by membrane-associated GSK3beta (Sus scrofa)


name: WNT3A stimulates the caveolin-dependent internalization of FZD5:p-LRP6 (Sus scrofa)


name: FRAT proteins bind GSK3beta (Sus scrofa)


name: DVL recruits GSK3beta:AXIN1 to the receptor complex (Sus scrofa)


name: Beta-catenin is released from the destruction complex (Sus scrofa)


name: Disassembly of the destruction complex and recruitment of AXIN to the membrane (Danio rerio)


name: Phosphorylation of LRP5/6 cytoplasmic domain by membrane-associated GSK3beta (Danio rerio)


name: WNT3A stimulates the caveolin-dependent internalization of FZD5:p-LRP6 (Danio rerio)


name: Disassembly of the destruction complex and recruitment of AXIN to the membrane (Gallus gallus)


name: WNT3A stimulates the caveolin-dependent internalization of FZD5:p-LRP6 (Gallus gallus)


name: FRAT proteins bind GSK3beta (Gallus gallus)


name: Phosphorylation of LRP5/6 cytoplasmic domain by membrane-associated GSK3beta (Gallus gallus)


name: DVL recruits GSK3beta:AXIN1 to the receptor complex (Gallus gallus)


name: Disassembly of the destruction complex and recruitment of AXIN to the membrane (Drosophila melanogaster)


name: Phosphorylation of LRP5/6 cytoplasmic domain by membrane-associated GSK3beta (Drosophila melanogaster)


name: DVL recruits GSK3beta:AXIN1 to the receptor complex (Drosophila melanogaster)


name: Deactivation of the beta-catenin transactivating complex (Caenorhabditis elegans)


name: TCF:Beta-catenin binds SOX proteins (Caenorhabditis elegans)


name: YWHAZ and XPO1 mediate the nuclear export of beta-catenin (Caenorhabditis elegans)


name: beta-catenin is replaced by repression complexes at the promoter (Caenorhabditis elegans)


name: Beta-catenin binds SOX proteins (Caenorhabditis elegans)


name: CHD8 binds beta-catenin to negatively regulate WNT-dependent gene expression (Caenorhabditis elegans)


name: Deactivation of the beta-catenin transactivating complex (Homo sapiens)


name: beta-catenin is replaced by repression complexes at the promoter (Homo sapiens)


name: YWHAZ and XPO1 mediate the nuclear export of beta-catenin (Homo sapiens)


name: Beta-catenin binds SOX proteins (Homo sapiens)


name: XIAP dissociates from ub-TLE (Homo sapiens)


name: CHD8 binds beta-catenin to negatively regulate WNT-dependent gene expression (Homo sapiens)


name: XPO1 binds the beta-catenin:CBY complex (Homo sapiens)


name: CTNNBIP1 binds beta-catenin (Homo sapiens)


name: APC promotes disassembly of beta-catenin transactivation complex (Homo sapiens)


name: TCF:Beta-catenin binds SOX proteins (Homo sapiens)


name: Deactivation of the beta-catenin transactivating complex (Mus musculus)


name: Beta-catenin binds SOX proteins (Mus musculus)


name: CHD8 binds beta-catenin to negatively regulate WNT-dependent gene expression (Mus musculus)


name: XIAP dissociates from ub-TLE (Mus musculus)


name: XPO1 binds the beta-catenin:CBY complex (Mus musculus)


name: TCF:Beta-catenin binds SOX proteins (Mus musculus)


name: beta-catenin is replaced by repression complexes at the promoter (Mus musculus)


name: YWHAZ and XPO1 mediate the nuclear export of beta-catenin (Mus musculus)


name: CTNNBIP1 binds beta-catenin (Mus musculus)


name: Deactivation of the beta-catenin transactivating complex (Rattus norvegicus)


name: AKT phosphorylates CBY1 (Rattus norvegicus)


name: YWHAZ binds p-CBY:CTNNB1 (Rattus norvegicus)


name: CBY1 binds beta-catenin (Rattus norvegicus)


name: beta-catenin is replaced by repression complexes at the promoter (Rattus norvegicus)


name: CHD8 binds beta-catenin to negatively regulate WNT-dependent gene expression (Rattus norvegicus)


name: TCF:Beta-catenin binds SOX proteins (Rattus norvegicus)


name: XIAP monoubiquinates TLE (Rattus norvegicus)


name: CTNNBIP1 binds beta-catenin (Rattus norvegicus)


name: YWHAZ and XPO1 mediate the nuclear export of beta-catenin (Rattus norvegicus)


name: XPO1 binds the beta-catenin:CBY complex (Rattus norvegicus)


name: Beta-catenin binds SOX proteins (Rattus norvegicus)


name: XIAP dissociates from ub-TLE (Rattus norvegicus)


name: Deactivation of the beta-catenin transactivating complex (Canis familiaris)


name: YWHAZ and XPO1 mediate the nuclear export of beta-catenin (Canis familiaris)


name: XIAP dissociates from ub-TLE (Canis familiaris)


name: TCF:Beta-catenin binds SOX proteins (Canis familiaris)


name: YWHAZ binds p-CBY:CTNNB1 (Canis familiaris)


name: CTNNBIP1 binds beta-catenin (Canis familiaris)


name: XIAP monoubiquinates TLE (Canis familiaris)


name: CBY1 binds beta-catenin (Canis familiaris)


name: Beta-catenin binds SOX proteins (Canis familiaris)


name: XPO1 binds the beta-catenin:CBY complex (Canis familiaris)


name: CHD8 binds beta-catenin to negatively regulate WNT-dependent gene expression (Canis familiaris)


name: beta-catenin is replaced by repression complexes at the promoter (Canis familiaris)


name: Deactivation of the beta-catenin transactivating complex (Bos taurus)


name: CHD8 binds beta-catenin to negatively regulate WNT-dependent gene expression (Bos taurus)


name: XIAP dissociates from ub-TLE (Bos taurus)


name: beta-catenin is replaced by repression complexes at the promoter (Bos taurus)


name: TCF:Beta-catenin binds SOX proteins (Bos taurus)


name: XPO1 binds the beta-catenin:CBY complex (Bos taurus)


name: CTNNBIP1 binds beta-catenin (Bos taurus)


name: YWHAZ and XPO1 mediate the nuclear export of beta-catenin (Bos taurus)


name: Beta-catenin binds SOX proteins (Bos taurus)


name: Deactivation of the beta-catenin transactivating complex (Sus scrofa)


name: TCF:Beta-catenin binds SOX proteins (Sus scrofa)


name: Beta-catenin binds SOX proteins (Sus scrofa)


name: beta-catenin is replaced by repression complexes at the promoter (Sus scrofa)


name: CTNNBIP1 binds beta-catenin (Sus scrofa)


name: XIAP dissociates from ub-TLE (Sus scrofa)


name: YWHAZ and XPO1 mediate the nuclear export of beta-catenin (Sus scrofa)


name: CHD8 binds beta-catenin to negatively regulate WNT-dependent gene expression (Sus scrofa)


name: Deactivation of the beta-catenin transactivating complex (Danio rerio)


name: XIAP dissociates from ub-TLE (Danio rerio)


name: YWHAZ and XPO1 mediate the nuclear export of beta-catenin (Danio rerio)


name: Beta-catenin binds SOX proteins (Danio rerio)


name: CTNNBIP1 binds beta-catenin (Danio rerio)


name: TCF:Beta-catenin binds SOX proteins (Danio rerio)


name: CHD8 binds beta-catenin to negatively regulate WNT-dependent gene expression (Danio rerio)


name: Deactivation of the beta-catenin transactivating complex (Xenopus tropicalis)


name: XIAP monoubiquinates TLE (Xenopus tropicalis)


name: YWHAZ binds p-CBY:CTNNB1 (Xenopus tropicalis)


name: CBY1 binds beta-catenin (Xenopus tropicalis)


name: YWHAZ and XPO1 mediate the nuclear export of beta-catenin (Xenopus tropicalis)


name: CHD8 binds beta-catenin to negatively regulate WNT-dependent gene expression (Xenopus tropicalis)


name: Beta-catenin binds SOX proteins (Xenopus tropicalis)


name: XIAP dissociates from ub-TLE (Xenopus tropicalis)


name: Deactivation of the beta-catenin transactivating complex (Gallus gallus)


name: YWHAZ and XPO1 mediate the nuclear export of beta-catenin (Gallus gallus)


name: YWHAZ binds p-CBY:CTNNB1 (Gallus gallus)


name: Beta-catenin binds SOX proteins (Gallus gallus)


name: beta-catenin is replaced by repression complexes at the promoter (Gallus gallus)


name: CTNNBIP1 binds beta-catenin (Gallus gallus)


name: XIAP dissociates from ub-TLE (Gallus gallus)


name: TCF:Beta-catenin binds SOX proteins (Gallus gallus)


name: XPO1 binds the beta-catenin:CBY complex (Gallus gallus)


name: XIAP monoubiquinates TLE (Gallus gallus)


name: Deactivation of the beta-catenin transactivating complex (Drosophila melanogaster)


name: beta-catenin is replaced by repression complexes at the promoter (Drosophila melanogaster)


name: YWHAZ binds p-CBY:CTNNB1 (Drosophila melanogaster)


name: TCF:Beta-catenin binds SOX proteins (Drosophila melanogaster)


name: YWHAZ and XPO1 mediate the nuclear export of beta-catenin (Drosophila melanogaster)


name: AKT phosphorylates CBY1 (Drosophila melanogaster)


name: XIAP monoubiquinates TLE (Drosophila melanogaster)


name: CHD8 binds beta-catenin to negatively regulate WNT-dependent gene expression (Drosophila melanogaster)


name: XIAP dissociates from ub-TLE (Drosophila melanogaster)


name: Beta-catenin binds SOX proteins (Drosophila melanogaster)


name: XPO1 binds the beta-catenin:CBY complex (Drosophila melanogaster)


name: XIAP binds TLE (Drosophila melanogaster)


name: CBY1 binds beta-catenin (Drosophila melanogaster)


name: Regulation of FZD by ubiquitination (Caenorhabditis elegans)


name: ZNRF3 ubiquitinates FZD to promote its downregulation (Caenorhabditis elegans)


name: Regulation of FZD by ubiquitination (Homo sapiens)


name: ZNRF3 autoubiquitinates to promote its internalization (Homo sapiens)


name: ZNRF3,RNF43 binds the FZD:LRP5/6 receptor complex (Homo sapiens)


name: RSPO:LGR binds ZNRF3 (Homo sapiens)


name: ZNRF3 ubiquitinates FZD to promote its downregulation (Homo sapiens)


name: USP8 deubiquitinates FZD to potentiate WNT signaling (Homo sapiens)


name: Regulation of FZD by ubiquitination (Mus musculus)


name: ZNRF3 ubiquitinates FZD to promote its downregulation (Mus musculus)


name: ZNRF3,RNF43 binds the FZD:LRP5/6 receptor complex (Mus musculus)


name: RSPO:LGR binds ZNRF3 (Mus musculus)


name: USP8 deubiquitinates FZD to potentiate WNT signaling (Mus musculus)


name: ZNRF3 autoubiquitinates to promote its internalization (Mus musculus)


name: Regulation of FZD by ubiquitination (Rattus norvegicus)


name: ZNRF3 ubiquitinates FZD to promote its downregulation (Rattus norvegicus)


name: ZNRF3,RNF43 binds the FZD:LRP5/6 receptor complex (Rattus norvegicus)


name: USP8 deubiquitinates FZD to potentiate WNT signaling (Rattus norvegicus)


name: RSPO:LGR binds ZNRF3 (Rattus norvegicus)


name: ZNRF3 autoubiquitinates to promote its internalization (Rattus norvegicus)


name: Regulation of FZD by ubiquitination (Canis familiaris)


name: ZNRF3 autoubiquitinates to promote its internalization (Canis familiaris)


name: RSPO:LGR binds ZNRF3 (Canis familiaris)


name: ZNRF3 ubiquitinates FZD to promote its downregulation (Canis familiaris)


name: Regulation of FZD by ubiquitination (Bos taurus)


name: RSPO:LGR binds ZNRF3 (Bos taurus)


name: ZNRF3 autoubiquitinates to promote its internalization (Bos taurus)


name: USP8 deubiquitinates FZD to potentiate WNT signaling (Bos taurus)


name: ZNRF3,RNF43 binds the FZD:LRP5/6 receptor complex (Bos taurus)


name: ZNRF3 ubiquitinates FZD to promote its downregulation (Bos taurus)


name: Regulation of FZD by ubiquitination (Sus scrofa)


name: ZNRF3 autoubiquitinates to promote its internalization (Sus scrofa)


name: RSPO:LGR binds ZNRF3 (Sus scrofa)


name: USP8 deubiquitinates FZD to potentiate WNT signaling (Sus scrofa)


name: ZNRF3,RNF43 binds the FZD:LRP5/6 receptor complex (Sus scrofa)


name: ZNRF3 ubiquitinates FZD to promote its downregulation (Sus scrofa)


name: Regulation of FZD by ubiquitination (Danio rerio)


name: RSPO:LGR binds ZNRF3 (Danio rerio)


name: ZNRF3 autoubiquitinates to promote its internalization (Danio rerio)


name: ZNRF3 ubiquitinates FZD to promote its downregulation (Danio rerio)


name: Regulation of FZD by ubiquitination (Xenopus tropicalis)


name: ZNRF3 ubiquitinates FZD to promote its downregulation (Xenopus tropicalis)


name: RSPO:LGR binds ZNRF3 (Xenopus tropicalis)


name: USP8 deubiquitinates FZD to potentiate WNT signaling (Xenopus tropicalis)


name: ZNRF3,RNF43 binds the FZD:LRP5/6 receptor complex (Xenopus tropicalis)


name: ZNRF3 autoubiquitinates to promote its internalization (Xenopus tropicalis)


name: Regulation of FZD by ubiquitination (Gallus gallus)


name: ZNRF3 autoubiquitinates to promote its internalization (Gallus gallus)


name: RSPO:LGR binds ZNRF3 (Gallus gallus)


name: ZNRF3 ubiquitinates FZD to promote its downregulation (Gallus gallus)


name: ZNRF3,RNF43 binds the FZD:LRP5/6 receptor complex (Gallus gallus)


name: USP8 deubiquitinates FZD to potentiate WNT signaling (Gallus gallus)


name: Formation of the beta-catenin:TCF transactivating complex (Caenorhabditis elegans)


name: Beta-catenin displaces TLE:HDAC1 from TCF/LEF (Caenorhabditis elegans)


name: Beta-catenin recruits CBP/p300 (Caenorhabditis elegans)


name: Beta-catenin recruits CDC73 and LEO1 (Caenorhabditis elegans)


name: Formation of the beta-catenin:TCF transactivating complex (Homo sapiens)


name: KAT5 HAT complex acetylates TCF4 gene at histone H4 (Homo sapiens)


name: Recruitment of SET1 methyltransferase complex (Homo sapiens)


name: Beta-catenin recruits CDC73 and LEO1 (Homo sapiens)


name: SET1 complex trimethylates H3K4 at the MYC gene (Homo sapiens)


name: Beta-catenin recruits CBP/p300 (Homo sapiens)


name: Beta-catenin recruits TRRAP/KAT5 HAT components (Homo sapiens)


name: Beta-catenin recruits SMARCA4 (Homo sapiens)


name: Beta-catenin:TCF associates with BCL9 and PYGO (Homo sapiens)


name: Beta-catenin displaces TLE:HDAC1 from TCF/LEF (Homo sapiens)


name: Binding of TCF/LEF:CTNNB1 to target gene promoters (Homo sapiens)


name: TCF/LEF:CTNNB1 promote transcription of AXIN2 (Homo sapiens)


name: TCF7L1/TCF7L2/LEF1:CTNNB1 promote transcription of the MYC gene (Homo sapiens)


name: TCF/LEF:CTNNB1 bind the AXIN2 gene (Homo sapiens)


name: TCF7L1/TCF7L2/LEF1:CTNNB1 bind the MYC gene (Homo sapiens)


name: Formation of the beta-catenin:TCF transactivating complex (Mus musculus)


name: Beta-catenin:TCF associates with BCL9 and PYGO (Mus musculus)


name: Beta-catenin recruits SMARCA4 (Mus musculus)


name: Beta-catenin displaces TLE:HDAC1 from TCF/LEF (Mus musculus)


name: Beta-catenin recruits TRRAP/KAT5 HAT components (Mus musculus)


name: Recruitment of SET1 methyltransferase complex (Mus musculus)


name: Beta-catenin recruits CBP/p300 (Mus musculus)


name: Beta-catenin recruits CDC73 and LEO1 (Mus musculus)


name: Formation of the beta-catenin:TCF transactivating complex (Rattus norvegicus)


name: Beta-catenin recruits CDC73 and LEO1 (Rattus norvegicus)


name: Beta-catenin recruits TRRAP/KAT5 HAT components (Rattus norvegicus)


name: Beta-catenin recruits SMARCA4 (Rattus norvegicus)


name: Beta-catenin displaces TLE:HDAC1 from TCF/LEF (Rattus norvegicus)


name: Beta-catenin recruits CBP/p300 (Rattus norvegicus)


name: Beta-catenin:TCF associates with BCL9 and PYGO (Rattus norvegicus)


name: Formation of the beta-catenin:TCF transactivating complex (Canis familiaris)


name: Beta-catenin recruits CBP/p300 (Canis familiaris)


name: Beta-catenin recruits TRRAP/KAT5 HAT components (Canis familiaris)


name: Beta-catenin recruits CDC73 and LEO1 (Canis familiaris)


name: Beta-catenin:TCF associates with BCL9 and PYGO (Canis familiaris)


name: Beta-catenin displaces TLE:HDAC1 from TCF/LEF (Canis familiaris)


name: Beta-catenin recruits SMARCA4 (Canis familiaris)


name: Recruitment of SET1 methyltransferase complex (Canis familiaris)


name: Formation of the beta-catenin:TCF transactivating complex (Bos taurus)


name: SET1 complex trimethylates H3K4 at the MYC gene (Bos taurus)


name: Beta-catenin:TCF associates with BCL9 and PYGO (Bos taurus)


name: Beta-catenin recruits CDC73 and LEO1 (Bos taurus)


name: Beta-catenin recruits TRRAP/KAT5 HAT components (Bos taurus)


name: Beta-catenin recruits CBP/p300 (Bos taurus)


name: Recruitment of SET1 methyltransferase complex (Bos taurus)


name: Beta-catenin displaces TLE:HDAC1 from TCF/LEF (Bos taurus)


name: Beta-catenin recruits SMARCA4 (Bos taurus)


name: Formation of the beta-catenin:TCF transactivating complex (Sus scrofa)


name: Beta-catenin recruits SMARCA4 (Sus scrofa)


name: Beta-catenin recruits TRRAP/KAT5 HAT components (Sus scrofa)


name: Beta-catenin recruits CDC73 and LEO1 (Sus scrofa)


name: Beta-catenin:TCF associates with BCL9 and PYGO (Sus scrofa)


name: Beta-catenin displaces TLE:HDAC1 from TCF/LEF (Sus scrofa)


name: Beta-catenin recruits CBP/p300 (Sus scrofa)


name: Formation of the beta-catenin:TCF transactivating complex (Danio rerio)


name: Beta-catenin:TCF associates with BCL9 and PYGO (Danio rerio)


name: Beta-catenin recruits TRRAP/KAT5 HAT components (Danio rerio)


name: Beta-catenin recruits SMARCA4 (Danio rerio)


name: Formation of the beta-catenin:TCF transactivating complex (Gallus gallus)


name: Beta-catenin recruits CDC73 and LEO1 (Gallus gallus)


name: Beta-catenin displaces TLE:HDAC1 from TCF/LEF (Gallus gallus)


name: Beta-catenin recruits SMARCA4 (Gallus gallus)


name: Beta-catenin recruits TRRAP/KAT5 HAT components (Gallus gallus)


name: SET1 complex trimethylates H3K4 at the MYC gene (Gallus gallus)


name: Beta-catenin recruits CBP/p300 (Gallus gallus)


name: Beta-catenin:TCF associates with BCL9 and PYGO (Gallus gallus)


name: Formation of the beta-catenin:TCF transactivating complex (Drosophila melanogaster)


name: Beta-catenin recruits TRRAP/KAT5 HAT components (Drosophila melanogaster)


name: Beta-catenin recruits CDC73 and LEO1 (Drosophila melanogaster)


name: Beta-catenin recruits CBP/p300 (Drosophila melanogaster)


name: Beta-catenin displaces TLE:HDAC1 from TCF/LEF (Drosophila melanogaster)


name: Recruitment of SET1 methyltransferase complex (Drosophila melanogaster)


name: SET1 complex trimethylates H3K4 at the MYC gene (Drosophila melanogaster)


name: Degradation of DVL (Caenorhabditis elegans)


name: DVL1 is bound by the HECT ubiquitin ligase HECW1 (Caenorhabditis elegans)


name: DVL is ubiquitinated by CUL3:KLHL12:RBX1 (Caenorhabditis elegans)


name: DVL1 is ubiquitinated by HECW1 (Caenorhabditis elegans)


name: Ubiquitinated DVL1 is degraded by the proteasome (Caenorhabditis elegans)


name: Ubiquitinated DVL1 is degraded by the proteasome (Homo sapiens)


name: DVL is ubiquitinated by CUL3:KLHL12:RBX1 (Homo sapiens)


name: Ubiquitinated DVL is degraded by the proteasome (Homo sapiens)


name: DVL1 is bound by the HECT ubiquitin ligase HECW1 (Homo sapiens)


name: DVL is bound by the CUL3:KLHL12:RBX1 ubiquitin ligase complex (Homo sapiens)


name: DVL1 is ubiquitinated by HECW1 (Homo sapiens)


name: DVL1 is ubiquitinated by HECW1 (Mus musculus)


name: DVL is ubiquitinated by CUL3:KLHL12:RBX1 (Mus musculus)


name: DVL1 is bound by the HECT ubiquitin ligase HECW1 (Mus musculus)


name: Ubiquitinated DVL is degraded by the proteasome (Mus musculus)


name: DVL is bound by the CUL3:KLHL12:RBX1 ubiquitin ligase complex (Mus musculus)


name: Ubiquitinated DVL1 is degraded by the proteasome (Mus musculus)


name: DVL1 is bound by the HECT ubiquitin ligase HECW1 (Rattus norvegicus)


name: DVL is bound by the CUL3:KLHL12:RBX1 ubiquitin ligase complex (Rattus norvegicus)


name: Ubiquitinated DVL is degraded by the proteasome (Rattus norvegicus)


name: DVL is ubiquitinated by CUL3:KLHL12:RBX1 (Rattus norvegicus)


name: DVL1 is ubiquitinated by HECW1 (Rattus norvegicus)


name: Ubiquitinated DVL1 is degraded by the proteasome (Rattus norvegicus)


name: Ubiquitinated DVL1 is degraded by the proteasome (Canis familiaris)


name: DVL1 is ubiquitinated by HECW1 (Canis familiaris)


name: DVL1 is bound by the HECT ubiquitin ligase HECW1 (Canis familiaris)


name: DVL is ubiquitinated by CUL3:KLHL12:RBX1 (Canis familiaris)


name: Ubiquitinated DVL is degraded by the proteasome (Bos taurus)


name: DVL is ubiquitinated by CUL3:KLHL12:RBX1 (Bos taurus)


name: DVL is bound by the CUL3:KLHL12:RBX1 ubiquitin ligase complex (Bos taurus)


name: DVL1 is bound by the HECT ubiquitin ligase HECW1 (Bos taurus)


name: Ubiquitinated DVL1 is degraded by the proteasome (Bos taurus)


name: DVL1 is ubiquitinated by HECW1 (Bos taurus)


name: Ubiquitinated DVL1 is degraded by the proteasome (Sus scrofa)


name: DVL1 is bound by the HECT ubiquitin ligase HECW1 (Sus scrofa)


name: DVL is ubiquitinated by CUL3:KLHL12:RBX1 (Sus scrofa)


name: DVL1 is ubiquitinated by HECW1 (Sus scrofa)


name: Ubiquitinated DVL is degraded by the proteasome (Sus scrofa)


name: DVL is bound by the CUL3:KLHL12:RBX1 ubiquitin ligase complex (Sus scrofa)


name: DVL is bound by the CUL3:KLHL12:RBX1 ubiquitin ligase complex (Danio rerio)


name: Ubiquitinated DVL is degraded by the proteasome (Danio rerio)


name: DVL is ubiquitinated by CUL3:KLHL12:RBX1 (Danio rerio)


name: DVL is ubiquitinated by CUL3:KLHL12:RBX1 (Xenopus tropicalis)


name: DVL is bound by the CUL3:KLHL12:RBX1 ubiquitin ligase complex (Gallus gallus)


name: DVL is ubiquitinated by CUL3:KLHL12:RBX1 (Gallus gallus)


name: Degradation of DVL (Drosophila melanogaster)


name: DVL1 is ubiquitinated by HECW1 (Drosophila melanogaster)


name: DVL is ubiquitinated by CUL3:KLHL12:RBX1 (Drosophila melanogaster)


name: Ubiquitinated DVL1 is degraded by the proteasome (Drosophila melanogaster)


name: DVL1 is bound by the HECT ubiquitin ligase HECW1 (Drosophila melanogaster)


name: Degradation of DVL (Dictyostelium discoideum)


name: DVL is ubiquitinated by CUL3:KLHL12:RBX1 (Dictyostelium discoideum)


name: Ubiquitinated DVL is degraded by the proteasome (Dictyostelium discoideum)


name: WNT ligand biogenesis and trafficking (Caenorhabditis elegans)


name: WNTs are secreted in exosomes (Caenorhabditis elegans)


name: Retromer recycles WLS to the Golgi (Caenorhabditis elegans)


name: WNT ligands traffic to the plasma membrane (Caenorhabditis elegans)


name: secretion of WNT ligands (Caenorhabditis elegans)


name: WLS:WNT complex is internalized for maturation into exosomes (Caenorhabditis elegans)


name: WLS dissociates from retromer (Caenorhabditis elegans)


name: Retromer associates with WLS (Caenorhabditis elegans)


name: WNT ligands traffic to the Golgi (Caenorhabditis elegans)


name: WLS is endocytosed to the early endosome (Caenorhabditis elegans)


name: WLS binds WNT ligands in the Golgi (Caenorhabditis elegans)


name: ppDVL binds DAAM1 (Caenorhabditis elegans)


name: ppDVL recruits RAC (Caenorhabditis elegans)


name: DVL is recruited to the receptor (Caenorhabditis elegans)


name: DAAM1 recruits GTP-bound RHOA (Caenorhabditis elegans)


name: WNT5A-dependent internalization of FZD4 (Caenorhabditis elegans)


name: WNT5A-FZD4 recruits DVL2 (Caenorhabditis elegans)


name: DVL2 is phosphorylated by PKC (Caenorhabditis elegans)


name: WNT5A binds FZD4 (Caenorhabditis elegans)


name: p-DVL2 recruits AP-2 and beta-arrestin 2 to promote clathrin-mediated endocytosis (Caenorhabditis elegans)


name: WNT5A:FZD4 is endocytosed (Caenorhabditis elegans)


name: WNT5A-dependent internalization of FZD4 (Homo sapiens)


name: p-DVL2 recruits AP-2 and beta-arrestin 2 to promote clathrin-mediated endocytosis (Homo sapiens)


name: DVL2 is phosphorylated by PKC (Homo sapiens)


name: WNT5A:FZD4 is endocytosed (Homo sapiens)


name: WNT5A-dependent internalization of FZD4 (Mus musculus)


name: p-DVL2 recruits AP-2 and beta-arrestin 2 to promote clathrin-mediated endocytosis (Mus musculus)


name: WNT5A:FZD4 is endocytosed (Mus musculus)


name: DVL2 is phosphorylated by PKC (Mus musculus)


name: WNT5A-dependent internalization of FZD4 (Rattus norvegicus)


name: WNT5A:FZD4 is endocytosed (Rattus norvegicus)


name: DVL2 is phosphorylated by PKC (Rattus norvegicus)


name: p-DVL2 recruits AP-2 and beta-arrestin 2 to promote clathrin-mediated endocytosis (Rattus norvegicus)


name: WNT5A-FZD4 recruits DVL2 (Rattus norvegicus)


name: WNT5A-dependent internalization of FZD4 (Canis familiaris)


name: WNT5A:FZD4 is endocytosed (Canis familiaris)


name: DVL2 is phosphorylated by PKC (Canis familiaris)


name: p-DVL2 recruits AP-2 and beta-arrestin 2 to promote clathrin-mediated endocytosis (Canis familiaris)


name: WNT5A-FZD4 recruits DVL2 (Canis familiaris)


name: WNT5A-dependent internalization of FZD4 (Bos taurus)


name: WNT5A:FZD4 is endocytosed (Bos taurus)


name: DVL2 is phosphorylated by PKC (Bos taurus)


name: p-DVL2 recruits AP-2 and beta-arrestin 2 to promote clathrin-mediated endocytosis (Bos taurus)


name: WNT5A-dependent internalization of FZD4 (Sus scrofa)


name: WNT5A:FZD4 is endocytosed (Sus scrofa)


name: DVL2 is phosphorylated by PKC (Sus scrofa)


name: p-DVL2 recruits AP-2 and beta-arrestin 2 to promote clathrin-mediated endocytosis (Sus scrofa)


name: WNT5A-dependent internalization of FZD4 (Xenopus tropicalis)


name: WNT5A:FZD4 is endocytosed (Xenopus tropicalis)


name: WNT5A-FZD4 recruits DVL2 (Xenopus tropicalis)


name: p-DVL2 recruits AP-2 and beta-arrestin 2 to promote clathrin-mediated endocytosis (Xenopus tropicalis)


name: DVL2 is phosphorylated by PKC (Xenopus tropicalis)


name: WNT5A-dependent internalization of FZD4 (Gallus gallus)


name: WNT5A-dependent internalization of FZD4 (Drosophila melanogaster)


name: WNT5A:FZD4 is endocytosed (Drosophila melanogaster)


name: WNT5A-dependent internalization of FZD2, FZD5 and ROR2 (Caenorhabditis elegans)


name: FZD2, FZD5 and ROR2 are internalized in a WNT5A and clathrin-dependent manner (Caenorhabditis elegans)


name: WNT5A binds FZD and ROR receptors (Caenorhabditis elegans)


name: WNT5A-dependent internalization of FZD2, FZD5 and ROR2 (Homo sapiens)


name: WNT5A binds FZD and ROR receptors (Homo sapiens)


name: FZD2, FZD5 and ROR2 are internalized in a WNT5A and clathrin-dependent manner (Homo sapiens)


name: WNT5A-dependent internalization of FZD2, FZD5 and ROR2 (Mus musculus)


name: WNT5A binds FZD and ROR receptors (Mus musculus)


name: FZD2, FZD5 and ROR2 are internalized in a WNT5A and clathrin-dependent manner (Mus musculus)


name: WNT5A-dependent internalization of FZD2, FZD5 and ROR2 (Rattus norvegicus)


name: FZD2, FZD5 and ROR2 are internalized in a WNT5A and clathrin-dependent manner (Rattus norvegicus)


name: WNT5A binds FZD and ROR receptors (Rattus norvegicus)


name: WNT5A-dependent internalization of FZD2, FZD5 and ROR2 (Canis familiaris)


name: FZD2, FZD5 and ROR2 are internalized in a WNT5A and clathrin-dependent manner (Canis familiaris)


name: WNT5A binds FZD and ROR receptors (Canis familiaris)


name: WNT5A-dependent internalization of FZD2, FZD5 and ROR2 (Bos taurus)


name: WNT5A binds FZD and ROR receptors (Bos taurus)


name: FZD2, FZD5 and ROR2 are internalized in a WNT5A and clathrin-dependent manner (Bos taurus)


name: WNT5A-dependent internalization of FZD2, FZD5 and ROR2 (Sus scrofa)


name: FZD2, FZD5 and ROR2 are internalized in a WNT5A and clathrin-dependent manner (Sus scrofa)


name: WNT5A binds FZD and ROR receptors (Sus scrofa)


name: WNT5A-dependent internalization of FZD2, FZD5 and ROR2 (Danio rerio)


name: WNT5A binds FZD and ROR receptors (Danio rerio)


name: WNT5A-dependent internalization of FZD2, FZD5 and ROR2 (Xenopus tropicalis)


name: WNT5A binds FZD and ROR receptors (Xenopus tropicalis)


name: FZD2, FZD5 and ROR2 are internalized in a WNT5A and clathrin-dependent manner (Xenopus tropicalis)


name: WNT5A-dependent internalization of FZD2, FZD5 and ROR2 (Gallus gallus)


name: FZD2, FZD5 and ROR2 are internalized in a WNT5A and clathrin-dependent manner (Gallus gallus)


name: WNT5A binds FZD and ROR receptors (Gallus gallus)


name: WNT5A-dependent internalization of FZD2, FZD5 and ROR2 (Drosophila melanogaster)


name: WNT5A binds FZD and ROR receptors (Drosophila melanogaster)


name: FZD2, FZD5 and ROR2 are internalized in a WNT5A and clathrin-dependent manner (Drosophila melanogaster)


name: Asymmetric localization of PCP proteins (Caenorhabditis elegans)


name: PRICKLE1 is degraded by the proteasome (Caenorhabditis elegans)


name: WNT5A binding to FZD promotes PRICKLE1 degradation (Caenorhabditis elegans)


name: Asymmetric localization of PCP proteins (Homo sapiens)


name: DVL2 is phosphorylated after WNT5A binding to FZD (Homo sapiens)


name: SCRIB is required for asymmetric membrane localization of VANGL2 (Homo sapiens)


name: VANGL2 is required for asymmetric membrane localization of FZD3 (Homo sapiens)


name: WNT5A binding to FZD promotes PRICKLE1 degradation (Homo sapiens)


name: SMURF1/2 ubiquitinates PRICKLE1 (Homo sapiens)


name: PRICKLE1 is degraded by the proteasome (Homo sapiens)


name: SMURF1/2 are recruited to the DVL2:PARD6A complex (Homo sapiens)


name: Asymmetric localization of PCP proteins (Mus musculus)


name: PRICKLE1 is degraded by the proteasome (Mus musculus)


name: WNT5A binding to FZD promotes PRICKLE1 degradation (Mus musculus)


name: SMURF1/2 are recruited to the DVL2:PARD6A complex (Mus musculus)


name: SMURF1/2 ubiquitinates PRICKLE1 (Mus musculus)


name: Asymmetric localization of PCP proteins (Rattus norvegicus)


name: SMURF1/2 are recruited to the DVL2:PARD6A complex (Rattus norvegicus)


name: PRICKLE1 is degraded by the proteasome (Rattus norvegicus)


name: WNT5A binding to FZD promotes PRICKLE1 degradation (Rattus norvegicus)


name: SMURF1/2 ubiquitinates PRICKLE1 (Rattus norvegicus)


name: Asymmetric localization of PCP proteins (Canis familiaris)


name: SMURF1/2 are recruited to the DVL2:PARD6A complex (Canis familiaris)


name: PRICKLE1 is degraded by the proteasome (Canis familiaris)


name: WNT5A binding to FZD promotes PRICKLE1 degradation (Canis familiaris)


name: SMURF1/2 ubiquitinates PRICKLE1 (Canis familiaris)


name: Asymmetric localization of PCP proteins (Bos taurus)


name: PRICKLE1 is degraded by the proteasome (Bos taurus)


name: SMURF1/2 are recruited to the DVL2:PARD6A complex (Bos taurus)


name: WNT5A binding to FZD promotes PRICKLE1 degradation (Bos taurus)


name: SMURF1/2 ubiquitinates PRICKLE1 (Bos taurus)


name: Asymmetric localization of PCP proteins (Sus scrofa)


name: WNT5A binding to FZD promotes PRICKLE1 degradation (Sus scrofa)


name: SMURF1/2 ubiquitinates PRICKLE1 (Sus scrofa)


name: SMURF1/2 are recruited to the DVL2:PARD6A complex (Sus scrofa)


name: PRICKLE1 is degraded by the proteasome (Sus scrofa)


name: Asymmetric localization of PCP proteins (Danio rerio)


name: PRICKLE1 is degraded by the proteasome (Danio rerio)


name: SMURF1/2 are recruited to the DVL2:PARD6A complex (Danio rerio)


name: SMURF1/2 ubiquitinates PRICKLE1 (Danio rerio)


name: WNT5A binding to FZD promotes PRICKLE1 degradation (Danio rerio)


name: Asymmetric localization of PCP proteins (Xenopus tropicalis)


name: WNT5A binding to FZD promotes PRICKLE1 degradation (Xenopus tropicalis)


name: Asymmetric localization of PCP proteins (Drosophila melanogaster)


name: SMURF1/2 ubiquitinates PRICKLE1 (Drosophila melanogaster)


name: PRICKLE1 is degraded by the proteasome (Drosophila melanogaster)


name: SMURF1/2 are recruited to the DVL2:PARD6A complex (Drosophila melanogaster)


name: WNT5A binding to FZD promotes PRICKLE1 degradation (Drosophila melanogaster)


name: VANGL2 is phosphorylated in response to WNT5A (Homo sapiens)


name: WNT5A binds ROR2 and VANGL2 (Homo sapiens)


name: WNT-dependent phosphorylation of DVL (Homo sapiens)


name: DVL is recruited to the receptor (Homo sapiens)


name: RYK binds WNT5A and VANGL2 (Homo sapiens)


name: DAAM1 recruits GTP-bound RHOA (Homo sapiens)


name: WNTs bind the FZD receptor to initiate PCP pathway (Homo sapiens)


name: DVL is recruited to the receptor (Mus musculus)


name: DAAM1 recruits GTP-bound RHOA (Mus musculus)


name: DAAM1 recruits GTP-bound RHOA (Rattus norvegicus)


name: DVL is recruited to the receptor (Rattus norvegicus)


name: DVL is recruited to the receptor (Canis familiaris)


name: DAAM1 recruits GTP-bound RHOA (Canis familiaris)


name: DAAM1 recruits GTP-bound RHOA (Bos taurus)


name: DVL is recruited to the receptor (Bos taurus)


name: DAAM1 recruits GTP-bound RHOA (Sus scrofa)


name: DVL is recruited to the receptor (Sus scrofa)


name: DAAM1 recruits GTP-bound RHOA (Danio rerio)


name: DVL is recruited to the receptor (Danio rerio)


name: DVL is recruited to the receptor (Xenopus tropicalis)


name: DAAM1 recruits GTP-bound RHOA (Xenopus tropicalis)


name: PCP/CE pathway (Drosophila melanogaster)


name: ppDVL binds DAAM1 (Drosophila melanogaster)


name: DVL is recruited to the receptor (Drosophila melanogaster)


name: DAAM1 recruits GTP-bound RHOA (Drosophila melanogaster)


name: ppDVL recruits RAC (Drosophila melanogaster)


name: Activation of Calcineurin (Caenorhabditis elegans)


name: Dissociation of CaM and CAMK2 autophosphorylation (Caenorhabditis elegans)


name: NLK translocates to nucleus (Caenorhabditis elegans)


name: Translocation of NFATC1:CaN:CaM to nucleus (Caenorhabditis elegans)


name: WNT:FZD complex promotes G-protein nucleotide exchange (Caenorhabditis elegans)


name: NLK phosphorylates TCF/LEF (Caenorhabditis elegans)


name: Active calmodulin binds CAMK2 (Caenorhabditis elegans)


name: G-protein subunits dissociate from WNT:FZD complex (Caenorhabditis elegans)


name: Autophosphorylation and activation of CAMK2 (Caenorhabditis elegans)


name: Dissociation of CaM and CAMK2 autophosphorylation (Homo sapiens)


name: Active calmodulin binds CAMK2 (Homo sapiens)


name: PDE6 hydrolyses cGMP to GMP (Homo sapiens)


name: G alpha t2 binds and activates PDE6 (Homo sapiens)


name: Autophosphorylation and activation of CAMK2 (Homo sapiens)


name: Activation of Calcineurin (Homo sapiens)


name: Decreasing cGMP concentration promotes intracellular Ca2+ release in response to WNT (Homo sapiens)


name: PRKG is activated by binding to high levels of cGMP in the absence of WNT signaling (Homo sapiens)


name: Gbeta:gamma activation of PLC beta (Homo sapiens)


name: Calcineurin binds and dephosphorylates NFAT1 in response to WNT/Ca2+ signaling (Homo sapiens)


name: TCF/LEF:CTNNB1 bind canonical WNT target promoters (Homo sapiens)


name: Translocation and activation of PKC alpha in response to WNT signaling (Homo sapiens)


name: Activation of MAP3K7 in response to WNT (Homo sapiens)


name: Transcription of canonical WNT targets is negatively regulated by NLK-dependent phosphorylation of TCF/LEF (Homo sapiens)


name: miR-92b binds 3'UTR of NLK mRNA (Homo sapiens)


name: Translocation of NFATC1:CaN:CaM to nucleus (Homo sapiens)


name: NLK translocates to nucleus (Homo sapiens)


name: NLK phosphorylates TCF/LEF (Homo sapiens)


name: PLC beta-mediated PIP2 hydrolysis (Homo sapiens)


name: WNT:FZD complex promotes G-protein nucleotide exchange (Homo sapiens)


name: WNT5A and WNT11 bind FZD receptors to initiate Ca2+ signaling (Homo sapiens)


name: G-protein subunits dissociate from WNT:FZD complex (Homo sapiens)


name: FZD recruits trimeric G-proteins (Homo sapiens)


name: NLK mRNA translation controlled by miR-92b (Homo sapiens)


name: NLK translocates to nucleus (Mus musculus)


name: Autophosphorylation and activation of CAMK2 (Mus musculus)


name: PDE6 hydrolyses cGMP to GMP (Mus musculus)


name: Activation of Calcineurin (Mus musculus)


name: NLK phosphorylates TCF/LEF (Mus musculus)


name: Dissociation of CaM and CAMK2 autophosphorylation (Mus musculus)


name: PLC beta-mediated PIP2 hydrolysis (Mus musculus)


name: Active calmodulin binds CAMK2 (Mus musculus)


name: Translocation of NFATC1:CaN:CaM to nucleus (Mus musculus)


name: Gbeta:gamma activation of PLC beta (Mus musculus)


name: G-protein subunits dissociate from WNT:FZD complex (Mus musculus)


name: WNT:FZD complex promotes G-protein nucleotide exchange (Mus musculus)


name: Calcineurin binds and dephosphorylates NFAT1 in response to WNT/Ca2+ signaling (Mus musculus)


name: Active calmodulin binds CAMK2 (Rattus norvegicus)


name: PDE6 hydrolyses cGMP to GMP (Rattus norvegicus)


name: NLK phosphorylates TCF/LEF (Rattus norvegicus)


name: Translocation of NFATC1:CaN:CaM to nucleus (Rattus norvegicus)


name: NLK translocates to nucleus (Rattus norvegicus)


name: Dissociation of CaM and CAMK2 autophosphorylation (Rattus norvegicus)


name: Activation of Calcineurin (Rattus norvegicus)


name: Calcineurin binds and dephosphorylates NFAT1 in response to WNT/Ca2+ signaling (Rattus norvegicus)


name: Autophosphorylation and activation of CAMK2 (Rattus norvegicus)


name: WNT:FZD complex promotes G-protein nucleotide exchange (Rattus norvegicus)


name: Calcineurin binds and dephosphorylates NFAT1 in response to WNT/Ca2+ signaling (Canis familiaris)


name: NLK translocates to nucleus (Canis familiaris)


name: Dissociation of CaM and CAMK2 autophosphorylation (Canis familiaris)


name: Gbeta:gamma activation of PLC beta (Canis familiaris)


name: Autophosphorylation and activation of CAMK2 (Canis familiaris)


name: G-protein subunits dissociate from WNT:FZD complex (Canis familiaris)


name: Active calmodulin binds CAMK2 (Canis familiaris)


name: Translocation of NFATC1:CaN:CaM to nucleus (Canis familiaris)


name: Activation of Calcineurin (Canis familiaris)


name: WNT:FZD complex promotes G-protein nucleotide exchange (Canis familiaris)


name: PDE6 hydrolyses cGMP to GMP (Canis familiaris)


name: PLC beta-mediated PIP2 hydrolysis (Canis familiaris)


name: NLK phosphorylates TCF/LEF (Canis familiaris)


name: Active calmodulin binds CAMK2 (Bos taurus)


name: Translocation of NFATC1:CaN:CaM to nucleus (Bos taurus)


name: Autophosphorylation and activation of CAMK2 (Bos taurus)


name: PDE6 hydrolyses cGMP to GMP (Bos taurus)


name: NLK translocates to nucleus (Bos taurus)


name: WNT:FZD complex promotes G-protein nucleotide exchange (Bos taurus)


name: G-protein subunits dissociate from WNT:FZD complex (Bos taurus)


name: Gbeta:gamma activation of PLC beta (Bos taurus)


name: PLC beta-mediated PIP2 hydrolysis (Bos taurus)


name: Dissociation of CaM and CAMK2 autophosphorylation (Bos taurus)


name: Calcineurin binds and dephosphorylates NFAT1 in response to WNT/Ca2+ signaling (Bos taurus)


name: PDE6 hydrolyses cGMP to GMP (Sus scrofa)


name: Translocation of NFATC1:CaN:CaM to nucleus (Sus scrofa)


name: Active calmodulin binds CAMK2 (Sus scrofa)


name: Autophosphorylation and activation of CAMK2 (Sus scrofa)


name: NLK translocates to nucleus (Sus scrofa)


name: Gbeta:gamma activation of PLC beta (Sus scrofa)


name: WNT:FZD complex promotes G-protein nucleotide exchange (Sus scrofa)


name: G-protein subunits dissociate from WNT:FZD complex (Sus scrofa)


name: Dissociation of CaM and CAMK2 autophosphorylation (Sus scrofa)


name: Calcineurin binds and dephosphorylates NFAT1 in response to WNT/Ca2+ signaling (Sus scrofa)


name: PLC beta-mediated PIP2 hydrolysis (Sus scrofa)


name: Gbeta:gamma activation of PLC beta (Xenopus tropicalis)


name: NLK translocates to nucleus (Xenopus tropicalis)


name: WNT:FZD complex promotes G-protein nucleotide exchange (Xenopus tropicalis)


name: PLC beta-mediated PIP2 hydrolysis (Xenopus tropicalis)


name: PDE6 hydrolyses cGMP to GMP (Xenopus tropicalis)


name: G-protein subunits dissociate from WNT:FZD complex (Xenopus tropicalis)


name: Autophosphorylation and activation of CAMK2 (Gallus gallus)


name: WNT:FZD complex promotes G-protein nucleotide exchange (Gallus gallus)


name: NLK translocates to nucleus (Gallus gallus)


name: G-protein subunits dissociate from WNT:FZD complex (Gallus gallus)


name: Active calmodulin binds CAMK2 (Gallus gallus)


name: PLC beta-mediated PIP2 hydrolysis (Gallus gallus)


name: PDE6 hydrolyses cGMP to GMP (Gallus gallus)


name: Dissociation of CaM and CAMK2 autophosphorylation (Gallus gallus)


name: Gbeta:gamma activation of PLC beta (Gallus gallus)


name: NLK phosphorylates TCF/LEF (Gallus gallus)


name: Translocation of NFATC1:CaN:CaM to nucleus (Gallus gallus)


name: Activation of Calcineurin (Gallus gallus)


name: Calcineurin binds and dephosphorylates NFAT1 in response to WNT/Ca2+ signaling (Gallus gallus)


name: Dissociation of CaM and CAMK2 autophosphorylation (Drosophila melanogaster)


name: CAMK2 binds MAP3K7 (Drosophila melanogaster)


name: Activation of NLK (Drosophila melanogaster)


name: Translocation of NFATC1:CaN:CaM to nucleus (Drosophila melanogaster)


name: NLK phosphorylates TCF/LEF (Drosophila melanogaster)


name: PLC beta-mediated PIP2 hydrolysis (Drosophila melanogaster)


name: NLK translocates to nucleus (Drosophila melanogaster)


name: Active calmodulin binds CAMK2 (Drosophila melanogaster)


name: Activation of Calcineurin (Drosophila melanogaster)


name: Gbeta:gamma activation of PLC beta (Drosophila melanogaster)


name: G-protein subunits dissociate from WNT:FZD complex (Drosophila melanogaster)


name: Calcineurin binds and dephosphorylates NFAT1 in response to WNT/Ca2+ signaling (Drosophila melanogaster)


name: Autophosphorylation and activation of CAMK2 (Drosophila melanogaster)


name: WNT:FZD complex promotes G-protein nucleotide exchange (Drosophila melanogaster)


name: Activation of Calcineurin (Dictyostelium discoideum)


name: NLK translocates to nucleus (Dictyostelium discoideum)


name: Translocation of NFATC1:CaN:CaM to nucleus (Dictyostelium discoideum)


name: Ca2+ pathway (Schizosaccharomyces pombe)


name: Translocation of NFATC1:CaN:CaM to nucleus (Schizosaccharomyces pombe)


name: Activation of Calcineurin (Schizosaccharomyces pombe)


name: NLK translocates to nucleus (Schizosaccharomyces pombe)


name: NLK translocates to nucleus (Saccharomyces cerevisiae)


name: Active calmodulin binds CAMK2 (Plasmodium falciparum)


name: Autophosphorylation and activation of CAMK2 (Plasmodium falciparum)


name: Translocation of NFATC1:CaN:CaM to nucleus (Plasmodium falciparum)


name: Activation of Calcineurin (Plasmodium falciparum)


name: Dissociation of CaM and CAMK2 autophosphorylation (Plasmodium falciparum)


name: NLK translocates to nucleus (Plasmodium falciparum)


name: HNF1B binds the LFNG gene (Homo sapiens)


name: Expression of WNT4 during nephron development (Homo sapiens)


name: Expression of LFNG during nephron development (Homo sapiens)


name: Expression of HNF4A during nephron development (Homo sapiens)


name: Expression of POU3F3 during nephron development (Homo sapiens)


name: HNF1B binds the HNF4A gene (Homo sapiens)


name: HNF1B binds the IRX1 gene (Homo sapiens)


name: Expression of JAG1 during nephron development (Homo sapiens)


name: Expression of DLL1 during nephron development (Homo sapiens)


name: Expression of IRX2 during nephron development (Homo sapiens)


name: HNF1B binds the IRX2 gene (Homo sapiens)


name: HNF1B binds the DLL1 gene (Homo sapiens)


name: HNF1B binds the WNT9B gene (Homo sapiens)


name: Expression of WNT9B during nephron development (Homo sapiens)


name: Expression of LHX1 during nephron development (Homo sapiens)


name: Expression of IRX1 during nephron development (Homo sapiens)


name: TCF dependent signaling in response to WNT (Homo sapiens)


name: Beta-catenin translocates to the nucleus (Homo sapiens)


name: Canonical WNT signaling through the atypical receptor RYK (Homo sapiens)


name: FZD recruits DVL to the receptor complex (Homo sapiens)


name: WNT binds to FZD and LRP5/6 (Homo sapiens)


name: USP34 deubiquitinates AXIN1,AXIN2 (Homo sapiens)


name: Negative regulation of TCF-dependent signaling by DVL-interacting proteins (Homo sapiens)


name: CXXC4 binds DVL to prevent AXIN binding (Homo sapiens)


name: AXIN is ubiquitinated by SMURF2 (Homo sapiens)


name: Ubiquitinated AXIN is degraded by the proteasome (Homo sapiens)


name: Ub-RibC-AXIN is degraded by the proteasome (Homo sapiens)


name: Tankyrase ADP-ribosylates AXIN (Homo sapiens)


name: RNF146 binds RibC-AXIN:TNKS complex (Homo sapiens)


name: RNF146 ubiquitinates ADP-ribosylated AXIN (Homo sapiens)


name: RNF146 ubiquitinates ADP-ribosylated AXIN (Mus musculus)


name: Ub-RibC-AXIN is degraded by the proteasome (Mus musculus)


name: RNF146 binds RibC-AXIN:TNKS complex (Mus musculus)


name: AXIN is ubiquitinated by SMURF2 (Mus musculus)


name: Ubiquitinated AXIN is degraded by the proteasome (Mus musculus)


name: Tankyrase ADP-ribosylates AXIN (Mus musculus)


name: Ubiquitinated AXIN is degraded by the proteasome (Rattus norvegicus)


name: Tankyrase binds AXIN (Rattus norvegicus)


name: AXIN is ubiquitinated by SMURF2 (Rattus norvegicus)


name: Tankyrase ADP-ribosylates AXIN (Rattus norvegicus)


name: RNF146 ubiquitinates ADP-ribosylated AXIN (Rattus norvegicus)


name: RNF146 binds RibC-AXIN:TNKS complex (Rattus norvegicus)


name: Ub-RibC-AXIN is degraded by the proteasome (Rattus norvegicus)


name: RNF146 ubiquitinates ADP-ribosylated AXIN (Canis familiaris)


name: RNF146 binds RibC-AXIN:TNKS complex (Canis familiaris)


name: Ub-RibC-AXIN is degraded by the proteasome (Canis familiaris)


name: Ubiquitinated AXIN is degraded by the proteasome (Canis familiaris)


name: Tankyrase ADP-ribosylates AXIN (Canis familiaris)


name: AXIN is ubiquitinated by SMURF2 (Canis familiaris)


name: RNF146 binds RibC-AXIN:TNKS complex (Bos taurus)


name: Ub-RibC-AXIN is degraded by the proteasome (Bos taurus)


name: AXIN is ubiquitinated by SMURF2 (Bos taurus)


name: Tankyrase ADP-ribosylates AXIN (Bos taurus)


name: RNF146 ubiquitinates ADP-ribosylated AXIN (Bos taurus)


name: Ubiquitinated AXIN is degraded by the proteasome (Bos taurus)


name: RNF146 ubiquitinates ADP-ribosylated AXIN (Sus scrofa)


name: AXIN is ubiquitinated by SMURF2 (Sus scrofa)


name: Tankyrase ADP-ribosylates AXIN (Sus scrofa)


name: RNF146 binds RibC-AXIN:TNKS complex (Sus scrofa)


name: Ub-RibC-AXIN is degraded by the proteasome (Sus scrofa)


name: Ubiquitinated AXIN is degraded by the proteasome (Sus scrofa)


name: AXIN is ubiquitinated by SMURF2 (Danio rerio)


name: Ubiquitinated AXIN is degraded by the proteasome (Danio rerio)


name: Degradation of AXIN (Xenopus tropicalis)


name: AXIN is ubiquitinated by SMURF2 (Xenopus tropicalis)


name: RNF146 ubiquitinates ADP-ribosylated AXIN (Gallus gallus)


name: AXIN is ubiquitinated by SMURF2 (Gallus gallus)


name: RNF146 binds RibC-AXIN:TNKS complex (Gallus gallus)


name: Tankyrase ADP-ribosylates AXIN (Gallus gallus)


name: Degradation of AXIN (Drosophila melanogaster)


name: SMURF2 binds AXIN (Drosophila melanogaster)


name: Ubiquitinated AXIN is degraded by the proteasome (Drosophila melanogaster)


name: AXIN is ubiquitinated by SMURF2 (Drosophila melanogaster)


name: Negative regulation of TCF-dependent signaling by WNT ligand antagonists (Homo sapiens)


name: DKK promotes clathrin-dependent internalization of LRP6 (Homo sapiens)


name: sFRP binds WNT3A and inhibits WNT:FZD binding (Homo sapiens)


name: Negative regulation of TCF-dependent signaling by WNT ligand antagonists (Mus musculus)


name: DKK promotes clathrin-dependent internalization of LRP6 (Mus musculus)


name: Negative regulation of TCF-dependent signaling by WNT ligand antagonists (Rattus norvegicus)


name: DKK promotes clathrin-dependent internalization of LRP6 (Rattus norvegicus)


name: DKK and KRM bind LRP5/6 (Rattus norvegicus)


name: Negative regulation of TCF-dependent signaling by WNT ligand antagonists (Bos taurus)


name: DKK promotes clathrin-dependent internalization of LRP6 (Bos taurus)


name: Negative regulation of TCF-dependent signaling by WNT ligand antagonists (Sus scrofa)


name: DKK promotes clathrin-dependent internalization of LRP6 (Sus scrofa)


name: Negative regulation of TCF-dependent signaling by WNT ligand antagonists (Xenopus tropicalis)


name: DKK promotes clathrin-dependent internalization of LRP6 (Xenopus tropicalis)


name: DKK and KRM bind LRP5/6 (Xenopus tropicalis)


name: Negative regulation of TCF-dependent signaling by WNT ligand antagonists (Gallus gallus)


name: Degradation of beta-catenin by the destruction complex (Homo sapiens)


name: Association of beta-catenin with the RBX1:SCF(beta-TrCP1) ubiquitin ligase complex (Homo sapiens)


name: Phosphorylation of APC component of the destruction complex (Homo sapiens)


name: Association of beta-catenin with the destruction complex (Homo sapiens)


name: Degradation of ubiquitinated beta catenin by the proteasome (Homo sapiens)


name: Multi-ubiquitination of phospho-beta-catenin by RBX1:SCF(beta-TrCP1) (Homo sapiens)


name: AXIN is phosphorylated in the destruction complex (Homo sapiens)


name: Assembly of the destruction complex (Homo sapiens)


name: Dissociation of beta-catenin from Axin and association of beta catenin with phospho-(20 aa) APC in the detruction complex (Homo sapiens)


name: APC is K63-polyubiquitinated (Homo sapiens)


name: Beta-catenin phosphorylation cascade (Homo sapiens)


name: Phosphorylation of phospho-(Ser45,Thr41,Ser37) at Ser33 by GSK-3 (Homo sapiens)


name: Phosphorylation of phospho-(Ser45 ) at Thr 41 by GSK-3 (Homo sapiens)


name: Phosphorylation of beta-catenin at Ser45 by CK1 alpha (Homo sapiens)


name: Phosphorylation of phospho- (Ser45, Thr41) beta-catenin  at Ser37 by GSK-3 (Homo sapiens)


name: Beta-catenin phosphorylation cascade (Mus musculus)


name: Phosphorylation of phospho-(Ser45,Thr41,Ser37) at Ser33 by GSK-3 (Mus musculus)


name: Phosphorylation of phospho- (Ser45, Thr41) beta-catenin  at Ser37 by GSK-3 (Mus musculus)


name: Phosphorylation of beta-catenin at Ser45 by CK1 alpha (Mus musculus)


name: Phosphorylation of phospho-(Ser45 ) at Thr 41 by GSK-3 (Mus musculus)


name: Beta-catenin phosphorylation cascade (Rattus norvegicus)


name: Phosphorylation of phospho- (Ser45, Thr41) beta-catenin  at Ser37 by GSK-3 (Rattus norvegicus)


name: Phosphorylation of phospho-(Ser45,Thr41,Ser37) at Ser33 by GSK-3 (Rattus norvegicus)


name: Phosphorylation of phospho-(Ser45 ) at Thr 41 by GSK-3 (Rattus norvegicus)


name: Phosphorylation of beta-catenin at Ser45 by CK1 alpha (Rattus norvegicus)


name: Beta-catenin phosphorylation cascade (Canis familiaris)


name: Phosphorylation of phospho-(Ser45 ) at Thr 41 by GSK-3 (Canis familiaris)


name: Phosphorylation of phospho-(Ser45,Thr41,Ser37) at Ser33 by GSK-3 (Canis familiaris)


name: Phosphorylation of beta-catenin at Ser45 by CK1 alpha (Canis familiaris)


name: Phosphorylation of phospho- (Ser45, Thr41) beta-catenin  at Ser37 by GSK-3 (Canis familiaris)


name: Beta-catenin phosphorylation cascade (Bos taurus)


name: Phosphorylation of phospho-(Ser45 ) at Thr 41 by GSK-3 (Bos taurus)


name: Phosphorylation of phospho-(Ser45,Thr41,Ser37) at Ser33 by GSK-3 (Bos taurus)


name: Phosphorylation of phospho- (Ser45, Thr41) beta-catenin  at Ser37 by GSK-3 (Bos taurus)


name: Phosphorylation of beta-catenin at Ser45 by CK1 alpha (Bos taurus)


name: Beta-catenin phosphorylation cascade (Sus scrofa)


name: Phosphorylation of beta-catenin at Ser45 by CK1 alpha (Sus scrofa)


name: Phosphorylation of phospho-(Ser45 ) at Thr 41 by GSK-3 (Sus scrofa)


name: Phosphorylation of phospho-(Ser45,Thr41,Ser37) at Ser33 by GSK-3 (Sus scrofa)


name: Phosphorylation of phospho- (Ser45, Thr41) beta-catenin  at Ser37 by GSK-3 (Sus scrofa)


name: Beta-catenin phosphorylation cascade (Gallus gallus)


name: Phosphorylation of beta-catenin at Ser45 by CK1 alpha (Gallus gallus)


name: Phosphorylation of phospho- (Ser45, Thr41) beta-catenin  at Ser37 by GSK-3 (Gallus gallus)


name: Phosphorylation of phospho-(Ser45,Thr41,Ser37) at Ser33 by GSK-3 (Gallus gallus)


name: Phosphorylation of phospho-(Ser45 ) at Thr 41 by GSK-3 (Gallus gallus)


name: Beta-catenin phosphorylation cascade (Drosophila melanogaster)


name: Phosphorylation of phospho-(Ser45 ) at Thr 41 by GSK-3 (Drosophila melanogaster)


name: Phosphorylation of beta-catenin at Ser45 by CK1 alpha (Drosophila melanogaster)


name: Phosphorylation of phospho- (Ser45, Thr41) beta-catenin  at Ser37 by GSK-3 (Drosophila melanogaster)


name: Phosphorylation of phospho-(Ser45,Thr41,Ser37) at Ser33 by GSK-3 (Drosophila melanogaster)


name: Beta-catenin phosphorylation cascade (Caenorhabditis elegans)


name: Phosphorylation of phospho- (Ser45, Thr41) beta-catenin  at Ser37 by GSK-3 (Caenorhabditis elegans)


name: Phosphorylation of beta-catenin at Ser45 by CK1 alpha (Caenorhabditis elegans)


name: Phosphorylation of phospho-(Ser45,Thr41,Ser37) at Ser33 by GSK-3 (Caenorhabditis elegans)


name: Phosphorylation of phospho-(Ser45 ) at Thr 41 by GSK-3 (Caenorhabditis elegans)


name: Repression of WNT target genes (Homo sapiens)


name: Transcription of canonical WNT targets is repressed by the TLE:HDAC and TCF/CTBP complexes (Homo sapiens)


name: TLE recruits HDAC1 to WNT promoters (Homo sapiens)


name: TCF/LEF binds WNT promoters (Homo sapiens)


name: TLE tetramers bind TCF/LEF at WNT promoters (Homo sapiens)


name: TCF7L2/TCF7L1 bind CTBP1 to repress WNT target genes (Homo sapiens)


name: TLE forms non-functional complexes with AES (Homo sapiens)


name: Repression of WNT target genes (Mus musculus)


name: TLE tetramers bind TCF/LEF at WNT promoters (Mus musculus)


name: TCF7L2/TCF7L1 bind CTBP1 to repress WNT target genes (Mus musculus)


name: Repression of WNT target genes (Rattus norvegicus)


name: TCF7L2/TCF7L1 bind CTBP1 to repress WNT target genes (Rattus norvegicus)


name: TLE tetramers bind TCF/LEF at WNT promoters (Rattus norvegicus)


name: Repression of WNT target genes (Canis familiaris)


name: TCF7L2/TCF7L1 bind CTBP1 to repress WNT target genes (Canis familiaris)


name: TLE tetramers bind TCF/LEF at WNT promoters (Canis familiaris)


name: Repression of WNT target genes (Bos taurus)


name: TCF7L2/TCF7L1 bind CTBP1 to repress WNT target genes (Bos taurus)


name: TLE tetramers bind TCF/LEF at WNT promoters (Bos taurus)


name: Repression of WNT target genes (Sus scrofa)


name: TCF7L2/TCF7L1 bind CTBP1 to repress WNT target genes (Sus scrofa)


name: TLE tetramers bind TCF/LEF at WNT promoters (Sus scrofa)


name: Repression of WNT target genes (Danio rerio)


name: TLE tetramers bind TCF/LEF at WNT promoters (Danio rerio)


name: Repression of WNT target genes (Xenopus tropicalis)


name: Repression of WNT target genes (Gallus gallus)


name: TCF7L2/TCF7L1 bind CTBP1 to repress WNT target genes (Gallus gallus)


name: TLE tetramers bind TCF/LEF at WNT promoters (Gallus gallus)


name: Repression of WNT target genes (Drosophila melanogaster)


name: TLE oligomerizes (Drosophila melanogaster)


name: TLE tetramers bind TCF/LEF at WNT promoters (Drosophila melanogaster)


name: TCF7L2/TCF7L1 bind CTBP1 to repress WNT target genes (Drosophila melanogaster)


name: Repression of WNT target genes (Caenorhabditis elegans)


name: TLE tetramers bind TCF/LEF at WNT promoters (Caenorhabditis elegans)


name: TCF7L2/TCF7L1 bind CTBP1 to repress WNT target genes (Caenorhabditis elegans)


name: TLE oligomerizes (Caenorhabditis elegans)


name: Degradation of beta-catenin by the destruction complex (Mus musculus)


name: Dissociation of beta-catenin from Axin and association of beta catenin with phospho-(20 aa) APC in the detruction complex (Mus musculus)


name: Multi-ubiquitination of phospho-beta-catenin by RBX1:SCF(beta-TrCP1) (Mus musculus)


name: Assembly of the destruction complex (Mus musculus)


name: Degradation of ubiquitinated beta catenin by the proteasome (Mus musculus)


name: Association of beta-catenin with the destruction complex (Mus musculus)


name: Association of beta-catenin with the RBX1:SCF(beta-TrCP1) ubiquitin ligase complex (Mus musculus)


name: Phosphorylation of APC component of the destruction complex (Mus musculus)


name: AXIN is phosphorylated in the destruction complex (Mus musculus)


name: Degradation of beta-catenin by the destruction complex (Rattus norvegicus)


name: Degradation of ubiquitinated beta catenin by the proteasome (Rattus norvegicus)


name: Association of beta-catenin with the destruction complex (Rattus norvegicus)


name: Assembly of the destruction complex (Rattus norvegicus)


name: Association of beta-catenin with the RBX1:SCF(beta-TrCP1) ubiquitin ligase complex (Rattus norvegicus)


name: Dissociation of beta-catenin from Axin and association of beta catenin with phospho-(20 aa) APC in the detruction complex (Rattus norvegicus)


name: Phosphorylation of APC component of the destruction complex (Rattus norvegicus)


name: AXIN is phosphorylated in the destruction complex (Rattus norvegicus)


name: Multi-ubiquitination of phospho-beta-catenin by RBX1:SCF(beta-TrCP1) (Rattus norvegicus)


name: Degradation of beta-catenin by the destruction complex (Canis familiaris)


name: Dissociation of beta-catenin from Axin and association of beta catenin with phospho-(20 aa) APC in the detruction complex (Canis familiaris)


name: Degradation of ubiquitinated beta catenin by the proteasome (Canis familiaris)


name: Association of beta-catenin with the RBX1:SCF(beta-TrCP1) ubiquitin ligase complex (Canis familiaris)


name: Phosphorylation of APC component of the destruction complex (Canis familiaris)


name: Association of beta-catenin with the destruction complex (Canis familiaris)


name: Multi-ubiquitination of phospho-beta-catenin by RBX1:SCF(beta-TrCP1) (Canis familiaris)


name: AXIN is phosphorylated in the destruction complex (Canis familiaris)


name: Assembly of the destruction complex (Canis familiaris)


name: Degradation of beta-catenin by the destruction complex (Bos taurus)


name: Phosphorylation of APC component of the destruction complex (Bos taurus)


name: Association of beta-catenin with the RBX1:SCF(beta-TrCP1) ubiquitin ligase complex (Bos taurus)


name: Degradation of ubiquitinated beta catenin by the proteasome (Bos taurus)


name: Assembly of the destruction complex (Bos taurus)


name: Dissociation of beta-catenin from Axin and association of beta catenin with phospho-(20 aa) APC in the detruction complex (Bos taurus)


name: AXIN is phosphorylated in the destruction complex (Bos taurus)


name: Multi-ubiquitination of phospho-beta-catenin by RBX1:SCF(beta-TrCP1) (Bos taurus)


name: Association of beta-catenin with the destruction complex (Bos taurus)


name: Degradation of beta-catenin by the destruction complex (Sus scrofa)


name: Association of beta-catenin with the RBX1:SCF(beta-TrCP1) ubiquitin ligase complex (Sus scrofa)


name: Phosphorylation of APC component of the destruction complex (Sus scrofa)


name: Dissociation of beta-catenin from Axin and association of beta catenin with phospho-(20 aa) APC in the detruction complex (Sus scrofa)


name: Assembly of the destruction complex (Sus scrofa)


name: Degradation of ubiquitinated beta catenin by the proteasome (Sus scrofa)


name: Multi-ubiquitination of phospho-beta-catenin by RBX1:SCF(beta-TrCP1) (Sus scrofa)


name: AXIN is phosphorylated in the destruction complex (Sus scrofa)


name: Association of beta-catenin with the destruction complex (Sus scrofa)


name: Degradation of beta-catenin by the destruction complex (Xenopus tropicalis)


name: Degradation of beta-catenin by the destruction complex (Gallus gallus)


name: Association of beta-catenin with the RBX1:SCF(beta-TrCP1) ubiquitin ligase complex (Gallus gallus)


name: Association of beta-catenin with the destruction complex (Gallus gallus)


name: Multi-ubiquitination of phospho-beta-catenin by RBX1:SCF(beta-TrCP1) (Gallus gallus)


name: Dissociation of beta-catenin from Axin and association of beta catenin with phospho-(20 aa) APC in the detruction complex (Gallus gallus)


name: AXIN is phosphorylated in the destruction complex (Gallus gallus)


name: Phosphorylation of APC component of the destruction complex (Gallus gallus)


name: Degradation of beta-catenin by the destruction complex (Drosophila melanogaster)


name: Multi-ubiquitination of phospho-beta-catenin by RBX1:SCF(beta-TrCP1) (Drosophila melanogaster)


name: Degradation of ubiquitinated beta catenin by the proteasome (Drosophila melanogaster)