name: negative regulation of telomere maintenance

description: Any process that stops, prevents, or reduces the frequency, rate or extent of a process that affects and monitors the activity of telomeric proteins and the length of telomeric DNA.


name: negative regulation of transcription by competitive promoter binding

category: biolink:BiologicalProcess biolink:Occurrent biolink:OntologyClass biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: Any process that stops, prevents, or reduces the frequency, rate or extent of DNA-dependent transcription using a mechanism that involves direct competition for interaction with a promoter binding site.


name: negative regulation of transcription by RNA polymerase III

description: Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase III.


name: negative regulation of pyruvate kinase activity

description: Any process that stops, prevents or reduces the frequency, rate or extent of pyruvate kinase activity.


name: negative regulation of poly(A)-specific ribonuclease activity

description: Any process that stops, prevents or reduces the frequency, rate or extent of poly(A)-specific ribonuclease activity.


name: negative regulation of double-strand break repair via single-strand annealing

description: Any process that stops, prevents or reduces the frequency, rate or extent of double-strand break repair via single-strand annealing.


name: negative regulation of exoribonuclease activity

description: Any process that stops, prevents or reduces the frequency, rate or extent of exoribonuclease activity.


name: negative regulation of transcription elongation by RNA polymerase I

description: Any process that stops, prevents or reduces the frequency, rate or extent of transcription elongation mediated by RNA polymerase I.


name: negative regulation of termination of RNA polymerase I transcription

description: Any process that stops, prevents or reduces the frequency, rate or extent of termination of RNA polymerase I transcription.


name: negative regulation of reciprocal meiotic recombination

description: Any process that decreases the frequency, rate or extent of recombination during meiosis. Reciprocal meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate.


name: negative regulation of transcription by transcription factor catabolism

description: Any process that stops, prevents, or reduces the frequency, rate or extent of DNA-dependent transcription using a mechanism that involves the catabolism of a sequence-specific DNA-binding transcription factor by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.


name: negative regulation of termination of DNA-templated transcription

description: Any process that decreases the rate, frequency or extent of DNA-dependent transcription termination, the process in which transcription is completed; the formation of phosphodiester bonds ceases, the RNA-DNA hybrid dissociates, and RNA polymerase releases the DNA.


name: negative regulation of telomere maintenance via semi-conservative replication

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the semi-conservative replication of telomeric DNA.


name: negative regulation of ribosomal protein gene transcription from RNA polymerase II promoter in response to nutrient levels

description: Any process that decreases the frequency, rate or extent of the synthesis of RNA from ribosomal protein genes by RNA polymerase II, originating at an RNA polymerase II promoter, as a result of a stimulus reflecting the presence, absence, or concentration of nutrients.


name: negative regulation of mitotic recombination

description: Any process that inhibits or decreases the rate of DNA recombination during mitosis.


name: negative regulation of snoRNA metabolic process

description: Any process that stops, prevents or reduces the frequency, rate or extent of snoRNA metabolic process.


negative regulation of DNA ligation

description: Any process that stops, prevents, or reduces the frequency, rate or extent of DNA ligation, the re-formation of a broken phosphodiester bond in the DNA backbone, carried out by DNA ligase.


name: negative regulation of protection from non-homologous end joining at telomere

description: Any process that stops, prevents or reduces the frequency, rate or extent of protection from non-homologous end joining at telomere.


name: negative regulation of t-circle formation

description: Any process that stops, prevents or reduces the frequency, rate or extent of t-circle formation.


mRNA stabilization

description: Prevention of degradation of mRNA molecules. In the absence of compensating changes in other processes, the slowing of mRNA degradation can result in an overall increase in the population of active mRNA molecules.


name: replication fork arrest at mating type locus

description: A process that impedes the progress of the DNA replication fork at natural replication fork pausing sites within the mating type locus.


name: negative regulation of purine nucleotide biosynthetic process

description: Any process that stops, prevents or reduces the frequency, rate or extent of purine nucleotide biosynthetic processes.


name: negative regulation of endoribonuclease activity

description: Any process that decreases the rate, frequency or extent of the catalysis of the hydrolysis of ester linkages within ribonucleic acid by creating internal breaks.


name: negative regulation of transcription elongation by RNA polymerase II

description: Any process that stops, prevents, or reduces the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides, catalyzed by RNA polymerase II.


name: negative regulation of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination

description: Any process that stops, prevents or reduces the frequency, rate or extent of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination.


name: negative regulation of NAD metabolic process

description: Any process that stops, prevents or reduces the frequency, rate or extent of NAD metabolic process.


name: negative regulation of apoptotic DNA fragmentation

description: Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic DNA fragmentation.


name: negative regulation of transcription of nucleolar large rRNA by RNA polymerase I

description: Any process that stops, prevents or reduces the frequency, rate or extent of transcription of nuclear large rRNA transcript mediated by RNA polymerase I.


RNA stabilization

description: Prevention of degradation of RNA molecules.


name: negative regulation of telomere maintenance via telomere lengthening

description: Any process that stops, prevents or reduces the frequency, rate or extent of telomere maintenance via telomere lengthening.


name: negative regulation of reverse transcription

description: Any process that stops, prevents or reduces the frequency, rate or extent of reverse transcription.


name: negative regulation of error-prone translesion synthesis

description: Any process that stops, prevents or reduces the frequency, rate or extent of error-prone translesion synthesis.


name: negative regulation of double-strand break repair via nonhomologous end joining

description: Any process that stops, prevents or reduces the frequency, rate or extent of double-strand break repair via nonhomologous end joining.


name: negative regulation of ribosomal protein gene transcription from RNA polymerase II promoter in response to stress

description: Any process that decreases the frequency, rate or extent of the synthesis of RNA from ribosomal protein genes by RNA polymerase II, originating at an RNA polymerase II promoter, as a result of a disturbance in organismal or cellular homeostasis.


name: negative regulation of mitotic recombination-dependent replication fork processing

description: Any process that inhibits or decreases the rate of mitotic recombination-dependent replication fork processing. Suppression of recombination at replication forks is necessary to prevent template switching.


name: negative regulation of mitotic DNA replication initiation from late origin

description: Any process that stops, prevents or reduces the frequency, rate or extent of firing from a late origin of replication involved in mitotic DNA replication.


name: negative regulation of telomere single strand break repair

description: Any process that stops, prevents or reduces the frequency, rate or extent of telomere single strand break repair.


name: negative regulation of nuclease activity

description: Any process that stops or reduces the rate of nuclease activity, the hydrolysis of ester linkages within nucleic acids.


name: negative regulation of RNA polymerase II transcription preinitiation complex assembly

description: Any process that stops, prevents, or reduces the frequency, rate or extent of RNA polymerase II transcriptional preinitiation complex assembly.


name: negative regulation of DNA ligase activity

description: Any process that stops, prevents or reduces the frequency, rate or extent of DNA ligase activity.


name: negative regulation of pyrimidine nucleotide biosynthetic process

description: Any process that stops, prevents or reduces the frequency, rate or extent of pyrimidine nucleotide biosynthetic process.


name: carbon catabolite repression of transcription by galactose

description: A transcription regulation process in which the presence of galactose that leads to a decrease in the frequency, rate, or extent of transcription of specific genes involved in the metabolism of other carbon sources. Carbon catabolite repression is a mechanism of genetic regulation which the accumulation of catabolites of one substance in the cell represses the formation of enzymes that contribute to the catabolism of other substances.


name: negative regulation of telomere maintenance via telomerase

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of telomeric repeats by telomerase.


name: negative regulation of guanylate cyclase activity

description: Any process that stops, prevents, or reduces the frequency, rate or extent of guanylate cyclase activity.


name: negative regulation of mRNA cis splicing, via spliceosome

description: Any process that stops, prevents or reduces the frequency, rate or extent of mRNA cis splicing, via spliceosome.


name: negative regulation of meiotic DNA double-strand break formation

description: Any process that stops, prevents or reduces the frequency, rate or extent of meiotic DNA double-strand break formation.


name: negative regulation of mRNA metabolic process

description: Any process that stops, prevents or reduces the frequency, rate or extent of mRNA metabolic process.


name: negative regulation of DNA endoreduplication

description: Any process that stops, prevents, or reduces the frequency, rate or extent of DNA endoreduplication.


name: negative regulation of mRNA catabolic process

description: Any process that stops, prevents or reduces the frequency, rate or extent of mRNA catabolic process.


name: negative regulation of purine nucleotide metabolic process

description: Any process that stops, prevents or reduces the frequency, rate or extent of purine nucleotide metabolic process.


telomerase RNA stabilization

description: Prevention of degradation of telomerase RNA (TERC) molecules.


name: negative regulation of DNA strand resection involved in replication fork processing

description: Any process that stops, prevents, or reduces the frequency, rate or extent of DNA strand resection involved in replication fork processing.


name: negative regulation of single strand break repair

description: Any process that stops, prevents or reduces the frequency, rate or extent of single strand break repair.


name: negative regulation of miRNA metabolic process

description: Any process that stops, prevents or reduces the frequency, rate or extent of miRNA metabolic process.


name: negative regulation of DNA primase activity

description: Any process that stops, prevents or reduces the frequency, rate or extent of DNA primase activity.


name: negative regulation of DNA metabolic process

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving DNA.


name: negative regulation of telomerase RNA reverse transcriptase activity

description: Any process that stops, prevents or reduces the frequency, rate or extent of telomerase RNA reverse transcriptase activity.


name: negative regulation of type III site-specific deoxyribonuclease activity

description: Any process that stops or reduces the rate of type III restriction endodeoxyribonuclease activity.


name: negative regulation of deadenylation-dependent decapping of nuclear-transcribed mRNA

description: Any process that stops, prevents, or reduces the frequency, rate or extent of deadenylation-dependent decapping of nuclear-transcribed mRNA.


name: negative regulation of lncRNA transcription

description: Any process that decreases the frequency, rate or extent of the synthesis of a lncRNA.


negative regulation of tRNA processing

description: Any process that stops, prevents, or reduces the frequency, rate or extent of tRNA processing.


name: negative regulation of nuclear-transcribed mRNA catabolic process, meiosis-specific transcripts

description: Any process that stops, prevents or reduces the frequency, rate or extent of selective degradation of meiosis-specific nuclear transcribed transcripts during vegetative growth, by a mechanism that requires determinant of selective removal (DSR) sequences in the targeted mRNAs and involves a YTH family protein.


name: negative regulation of DNA amplification

description: Any process that stops, prevents or reduces the frequency, rate or extent of DNA amplification.


name: negative regulation of snoRNA processing

description: Any process that stops, prevents or reduces the frequency, rate or extent of snoRNA processing.


name: negative regulation of telomeric loop disassembly

description: Any process that stops, prevents or reduces the frequency, rate or extent of telomeric loop disassembly.


3'-UTR-mediated mRNA stabilization

description: An mRNA stabilization process in which one or more RNA-binding proteins associate with the 3'-untranslated region (UTR) of an mRNA.


replication fork arrest at tRNA locus

description: A process that impedes the progress of the DNA replication fork at natural replication fork pausing sites within the eukaryotic tRNA transcription unit.


name: negative regulation of snRNA transcription by RNA polymerase II

description: Any process that stops, prevents or reduces the frequency, rate or extent of snRNA transcription mediated by RNA polymerase II.


name: negative regulation of mitotic cell cycle DNA replication

description: Any process that stops, prevents or reduces the frequency, rate or extent of mitotic cell cycle DNA replication.


name: negative regulation of RNA metabolic process

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving RNA.


name: negative regulation of nucleotide biosynthetic process

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nucleotides.


name: negative regulation of pyrimidine nucleobase metabolic process

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving pyrimidine nucleobases.


name: negative regulation of exodeoxyribonuclease activity

description: Any process that stops, prevents or reduces the frequency, rate or extent of exodeoxyribonuclease activity.


name: negative regulation of telomere maintenance in response to DNA damage

description: Any process that stops, prevents or reduces the frequency, rate or extent of telomere maintenance in response to DNA damage.


name: negative regulation of nuclear-transcribed mRNA poly(A) tail shortening

description: Any process that decreases the frequency, rate or extent of poly(A) tail shortening of a nuclear-transcribed mRNA. Poly(A) tail shortening is the decrease in length of the poly(A) tail of an mRNA from full length to an oligo(A) length.


inactivation of recombination (HML)

description: The inactivation of recombination at sequences around a mating type donor locus, with the consequence that the other donor is the only one available for mating type switching; exemplified by the HML locus and surrounding sequences on Chromosome III in Saccharomyces cerevisiae.


name: negative regulation of transcription by RNA polymerase I

description: Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase I.


name: negative regulation of DNA-templated DNA replication

description: Any process that stops, prevents, or reduces the frequency, rate or extent of DNA-dependent DNA replication.


name: negative regulation of mRNA modification

description: Any process that decreases the rate, frequency, or extent of the covalent alteration of one or more nucleotides within an mRNA molecule to produce an mRNA molecule with a sequence that differs from that coded genetically.


name: negative regulation of type I site-specific deoxyribonuclease activity

description: Any process that stops or reduces the rate of type I restriction endodeoxyribonuclease activity.


name: negative regulation of double-strand break repair

description: Any process that stops, prevents or reduces the frequency, rate or extent of double-strand break repair.


name: negative regulation of telomerase activity

description: Any process that stops or reduces the activity of the enzyme telomerase, which catalyzes of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).


negative regulation of telomere capping

description: Any process that stops, prevents or reduces the frequency, rate or extent of telomere capping.


name: negative regulation of DNA-templated transcription, elongation

description: Any process that stops, prevents, or reduces the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides catalyzed by a DNA-dependent RNA polymerase.


name: negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

description: Any process that stops, prevents or reduces the frequency, rate or extent of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay.


name: negative regulation of mating-type specific transcription, DNA-templated

description: Any mating-type specific process that stops, prevents or reduces the rate of cellular DNA-templated transcription.


name: negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

description: Any process that stops, prevents or reduces the frequency, rate or extent of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay.


name: nitrogen catabolite repression of transcription from RNA polymerase II promoter

description: A transcription regulation process in which the presence of one nitrogen source leads to a decrease in the frequency, rate, or extent of transcription, from an RNA polymerase II promoter, of specific genes involved in the metabolism of other nitrogen sources.


name: negative regulation of type II site-specific deoxyribonuclease activity

description: Any process that stops or reduces the rate of type II restriction endodeoxyribonuclease activity.


name: negative regulation of double-strand break repair via homologous recombination

description: Any process that stops, prevents, or reduces the frequency, rate or extent of double-strand break repair via homologous recombination.


name: negative regulation of endodeoxyribonuclease activity

description: Any process that stops or reduces the rate of endodeoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid by creating internal breaks.


name: negative regulation of mitochondrial RNA catabolic process

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving catabolism in the mitochondrion of RNA transcribed from the mitochondrial genome.


negative regulation of mRNA processing

description: Any process that stops, prevents, or reduces the frequency, rate or extent of mRNA processing.


name: negative regulation of DNA-templated DNA replication initiation

description: Any process that stops, prevents, or reduces the frequency, rate or extent of initiation of DNA-dependent DNA replication.


name: negative regulation of type IV site-specific deoxyribonuclease activity

description: Any process that stops or reduces the rate of type IV restriction endodeoxyribonuclease activity.


name: negative regulation of DNA recombination at centromere

description: Any process that stops, prevents, or reduces the frequency, rate or extent of genetic recombination at the centromere.


negative regulation of mismatch repair

description: Any process that stops, prevents, or reduces the frequency, rate or extent of mismatch repair.


replication fork arrest

description: Any process that stops, prevents, or reduces the frequency, rate or extent of DNA replication by impeding the progress of the DNA replication fork. Replication fork arrest is one of the 'quality control' processes ensuring that DNA-dependent DNA replication occurs correctly. DNA replication fork arrest during DNA-dependent DNA replication is not known to occur outside of cases where a replication error needs to be prevented or corrected.


name: negative regulation of single stranded viral RNA replication via double stranded DNA intermediate

description: Any process that stops, prevents, or reduces the frequency, rate or extent of single stranded viral RNA replication via double stranded DNA intermediate.


name: negative regulation of miRNA transcription

description: Any process that stops, prevents or reduces the frequency, rate or extent of microRNA (miRNA) gene transcription.


name: negative regulation of transcription from RNA polymerase II promoter by a nonfermentable carbon source

description: A transcription regulation process in which the presence of a nonfermentable carbon source leads to a decrease of the frequency, rate, or extent of transcription, from an RNA polymerase II promoter, of specific genes involved in the metabolism of other carbon sources.


name: negative regulation of snRNA pseudouridine synthesis

description: Any process that stops, prevents or reduces the frequency, rate or extent of snRNA pseudouridine synthesis.


name: negative regulation of DNA catabolic process

description: Any process that stops, prevents or reduces the frequency, rate or extent of DNA catabolic process.


name: negative regulation of tRNA metabolic process

description: Any process that stops, prevents or reduces the frequency, rate or extent of tRNA metabolic process.


name: negative regulation of transcription by transcription factor localization

description: Any process that stops, prevents, or reduces the frequency, rate or extent of DNA-dependent transcription using a mechanism that involves the localization of a transcription factor.


name: negative regulation of telomere maintenance via recombination

description: Any process that stops, prevents, or reduces the frequency, rate or extent of a recombinational process involved in the maintenance of proper telomeric length.


name: negative regulation of mRNA 3'-end processing

description: Any process that stops, prevents, or reduces the frequency, rate or extent of mRNA 3'-end processing.


name: negative regulation of mitochondrial DNA metabolic process

description: Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrial DNA metabolic process.


name: negative regulation of nucleoside metabolic process

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving nucleosides.


name: negative regulation of transcription by RNA polymerase V

description: Any process that stops, prevents or reduces the frequency, rate or extent of transcription mediated by RNA polymerase V.


name: negative regulation of telomeric D-loop disassembly

description: Any process that stops, prevents or reduces the frequency, rate or extent of telomeric D-loop disassembly.


name: negative regulation of ribosomal protein gene transcription by RNA polymerase II

description: Any process that decreases the frequency, rate or extent of the synthesis of RNA from ribosomal protein genes mediated by RNA polymerase II.


name: negative regulation of mitochondrial mRNA catabolic process

description: Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrial mRNA catabolic process.


name: negative regulation of mitochondrial DNA replication

description: Any process that decreases the rate, frequency or extent of the process in which new strands of DNA are synthesized in the mitochondrion.


name: negative regulation of nuclear cell cycle DNA replication

description: Any process that stops, prevents or reduces the frequency, rate or extent of nuclear cell cycle DNA replication.


tRNA stabilization

description: Prevention of degradation of tRNA molecules.


name: negative regulation of deoxyribonuclease activity

description: Any process that stops or reduces the rate of deoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid.


name: negative regulation of glycolytic process through fructose-6-phosphate

description: Any process that stops, prevents or reduces the frequency, rate or extent of glycolytic process through fructose-6-phosphate.


name: negative regulation of mRNA splicing, via spliceosome

description: Any process that stops, prevents or reduces the rate or extent of mRNA splicing via a spliceosomal mechanism.


negative regulation of rRNA processing

description: Any process that stops, prevents, or reduces the frequency, rate or extent of rRNA processing.


CRD-mediated mRNA stabilization

description: An mRNA stabilization process in which one or more RNA-binding proteins associate with a sequence in the open reading frame called the coding region instability determinant (CRD).


name: negative regulation of DNA replication initiation involved in plasmid copy number maintenance

description: Any process that decreases the frequency, rate or extent of initiation of plasmid DNA replication that contributes to copy number maintenance.


name: negative regulation of mitotic DNA replication initiation

description: Any process that stops, prevents or reduces the frequency, rate or extent of DNA replication initiation involved in mitotic DNA replication.


name: negative regulation of promoter clearance from RNA polymerase II promoter

description: A process that stops, prevents or reduces the transition from the initiation to the elongation phases of transcription by RNA polymerase II.


name: negative regulation of restriction endodeoxyribonuclease activity

description: Any process that stops or reduces the rate of a restriction endodeoxyribonuclease activity, the catalysis of endonucleolytic cleavage of DNA in a site-specific manner, resulting in double-strand breaks.


name: negative regulation of miRNA catabolic process

description: Any process that stops, prevents or reduces the frequency, rate or extent of miRNA catabolic process.


name: negative regulation of exonuclease activity

description: Any process that stops, prevents or reduces the frequency, rate or extent of exonuclease activity.


name: carbon catabolite repression of transcription from RNA polymerase II promoter

description: A transcription regulation process in which the presence of one carbon source leads to a decrease in the frequency, rate, or extent of transcription, from an RNA polymerase II promoter, of specific genes involved in the metabolism of other carbon sources.


name: negative regulation of initiation of premeiotic DNA replication

description: Any process that stops, prevents or reduces the frequency, rate or extent of initiation of premeiotic DNA replication.


name: negative regulation of DNA-directed DNA polymerase activity

description: Any process that stops, prevents or reduces the frequency, rate or extent of DNA-directed DNA polymerase activity.


name: negative regulation of purine nucleotide catabolic process

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of purine nucleotides.


name: negative regulation of tRNA catabolic process

description: Any process that stops, prevents or reduces the frequency, rate or extent of tRNA catabolic process.


name: replication fork arrest involved in DNA replication termination

description: A replication fork arrest process that contributes to the termination of DNA replication.


replication fork arrest at rDNA repeats

description: A process that impedes the progress of the DNA replication fork at natural replication fork pausing sites within the eukaryotic rDNA repeat spacer.


negative regulation of strand invasion

description: Any process that decreases the rate, frequency or extent of strand invasion. Strand invasion is the process in which the nucleoprotein complex (composed of the broken single-strand DNA and the recombinase) searches and identifies a region of homology in intact duplex DNA. The broken single-strand DNA displaces the like strand and forms Watson-Crick base pairs with its complement, forming a duplex in which each strand is from one of the two recombining DNA molecules.


name: negative regulation of DNA-templated transcription

description: Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.


name: negative regulation of termination of RNA polymerase II transcription

description: Any process that stops, prevents or reduces the frequency, rate or extent of termination of RNA polymerase II transcription.


name: nitrogen catabolite repression of transcription

description: A transcription regulation process in which the presence of one nitrogen source leads to a decrease in the frequency, rate, or extent of transcription of specific genes involved in the metabolism of other nitrogen sources.


name: negative regulation of nucleotide catabolic process

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of nucleotides.


name: negative regulation of RNA catabolic process

description: Any process that stops, prevents or reduces the frequency, rate or extent of RNA catabolic process.


name: negative regulation of ribonuclease activity

description: Any process that decreases the rate, frequency, or extent of ribonuclease activity, catalysis of the hydrolysis of phosphodiester bonds in chains of RNA.


name: negative regulation of antisense RNA transcription

description: Any process that decreases the frequency, rate or extent of the synthesis of antisense RNA, an RNA molecule complementary in sequence to another RNA or DNA molecule, which, by binding the latter, acts to inhibit its function and/or completion of synthesis, on a template of DNA.


name: negative regulation of DNA recombination

description: Any process that stops, prevents, or reduces the frequency, rate or extent of DNA recombination.


name: negative regulation of double-strand break repair via break-induced replication

description: Any process that stops, prevents or reduces the frequency, rate or extent of double-strand break repair via break-induced replication.


name: negative regulation of DNA biosynthetic process

description: Any process that stops, prevents or reduces the frequency, rate or extent of DNA biosynthetic process.


name: negative regulation of termination of RNA polymerase II transcription, poly(A)-coupled

description: Any process that stops, prevents or reduces the frequency, rate or extent of termination of RNA polymerase II transcription, poly(A)-coupled.


name: negative regulation of base-excision repair

description: Any process that stops, prevents or reduces the frequency, rate or extent of base-excision repair.


name: negative regulation of DNA-templated transcription initiation

description: Any process that stops, prevents, or reduces the frequency, rate or extent of DNA-templated transcription initiation.


name: negative regulation of nucleotide metabolic process

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving nucleotides.


name: negative regulation of RNA polymerase III activity

description: Any process that stops, prevents or reduces the frequency, rate or extent of RNA polymerase III activity.


name: negative regulation of ribosomal protein gene transcription from RNA polymerase II promoter in response to chemical stimulus

description: Any process that decreases the frequency, rate or extent of the synthesis of RNA from ribosomal protein genes by RNA polymerase II, originating at an RNA polymerase II promoter, as a result of a chemical stimulus.


name: carbon catabolite repression of transcription from RNA polymerase II promoter by galactose

description: Any process involving galactose that stops, prevents or reduces the rate of transcription from an RNA polymerase II promoter.


name: negative regulation of purine nucleobase metabolic process

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving purine nucleobases.


negative regulation of DNA replication

description: Any process that stops, prevents, or reduces the frequency, rate or extent of DNA replication.


transcription antitermination

description: A positive regulation of gene expression mechanism that allows RNA polymerase to continue transcription beyond a termination site, thus allowing expression of downstream genes under specific conditions.


name: carbon catabolite repression of transcription

description: A transcription regulation process in which the presence of one carbon source leads to a decrease in the frequency, rate, or extent of transcription of specific genes involved in the metabolism of other carbon sources. Carbon catabolite repression is a mechanism of genetic regulation which the accumulation of catabolites of one substance in the cell represses the formation of enzymes that contribute to the catabolism of other substances.


negative regulation of DNA repair

description: Any process that stops, prevents, or reduces the frequency, rate or extent of DNA repair.


name: negative regulation of RNA biosynthetic process

description: Any process that stops, prevents or reduces the frequency, rate or extent of RNA biosynthetic process.


name: cytotoxic and regulatory T-cell molecule isoform h1 (human)

description: A cytotoxic and regulatory T-cell molecule (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O95727-1.


name: cytotoxic and regulatory T-cell molecule

description: A protein that is a translation product of the human CRTAM gene or a 1:1 ortholog thereof.


name: cytotoxic and regulatory T-cell molecule isoform h2 (human)

description: A cytotoxic and regulatory T-cell molecule (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O95727-2.


name: cytotoxic and regulatory T-cell molecule O-glycosylated 1 (human)

description: A cytotoxic and regulatory T-cell molecule (human) that has been O-glycosylated at the residue equivalent to Thr-271 of the amino acid sequence represented by UniProtKB:O95727-1, in which the glycan composition is represented by GlyTouCan:G53434XO. Example: UniProtKB:O95727-1, Thr-271, MOD:00005~GNO:G53434XO.


name: cytotoxic and regulatory T-cell molecule isoform m3 (mouse)

description: A cytotoxic and regulatory T-cell molecule (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q149L7-3.


name: cytotoxic and regulatory T-cell molecule O-glycosylated 2 (human)

description: A cytotoxic and regulatory T-cell molecule (human) that has been O-glycosylated at the residue equivalent to Thr-272 of the amino acid sequence represented by UniProtKB:O95727-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:O95727-1, Thr-272, MOD:00005~GNO:G43417UB.


name: cytotoxic and regulatory T-cell molecule isoform m1 (mouse)

description: A cytotoxic and regulatory T-cell molecule (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q149L7-1.


name: cytotoxic and regulatory T-cell molecule, signal peptide removed form (human)

description: A cytotoxic and regulatory T-cell molecule (human) that has had the signal peptide removed. Example: UniProtKB:O95727-1, 18-393.


name: cytotoxic and regulatory T-cell molecule isoform m2 (mouse)

description: A cytotoxic and regulatory T-cell molecule (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q149L7-2.


name: Ras-related protein Rab-3B phosphorylated 1 (mouse)

description: A Ras-related protein Rab-3B phosphorylated 1 in mouse. UniProtKB:Q9CZT8, Ser-188, MOD:00046.


name: RNA-binding protein MEX3D isoform m1 (mouse)

description: An RNA-binding protein MEX3D (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q3UE17-1.


name: MEX3D_MOUSE RNA-binding protein MEX3D (sprot)

description: An RNA-binding protein MEX3D that is encoded in the genome of mouse.


name: RNA-binding protein MEX3D isoform m2 (mouse)

description: An RNA-binding protein MEX3D (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q3UE17-2.


H2B7_CHICK Histone H2B 7 (sprot)

A protein that is a translation product of any of the 2 copies of the H2B-VII gene in chicken.


name: DNA-dependent protein kinase catalytic subunit deaminated 6 (human)

description: A DNA-dependent protein kinase catalytic subunit (human) that has been deaminated on the residue at the position equivalent to Asn-3580 of the amino acid sequence represented by UniProtKB:P78527-1. Example: UniProtKB:P78527-1, Asn-3580, MOD:00684.


name: SORC3_MOUSE VPS10 domain-containing receptor SorCS3 (sprot)

description: A VPS10 domain-containing receptor SorCS3 that is encoded in the genome of mouse.


name: ubiquitin carboxyl-terminal hydrolase usp-48 isoform a (worm)

description: A ubiquitin carboxyl-terminal hydrolase usp-48 (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:G5ECC7-1.


cadherin-13 isoform h4 (human)

A cadherin-13 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P55290-4.


CAD13_HUMAN Cadherin-13 (sprot)

A cadherin-13 that is encoded in the genome of human.


cadherin-13 isoform h5 (human)

A cadherin-13 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P55290-5.


cadherin-13 isoform h1 (human)

A cadherin-13 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P55290-1.


cadherin-13 phosphorylated 1 (human)

A cadherin-13 (human) that has been phosphorylated on the residue at the position equivalent to Ser-14 of the amino acid sequence represented by UniProtKB:P55290-1. Example: UniProtKB:P55290-1, Ser-14, MOD:00046.


cadherin-13 isoform h2 (human)

A cadherin-13 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P55290-2.


cadherin-13 isoform h3 (human)

A cadherin-13 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P55290-3.


name: PTGR1_RAT Prostaglandin reductase 1 (sprot)

description: A prostaglandin reductase 1 that is encoded in the genome of rat.


name: prostaglandin reductase 1 isoform 1 (rat)

description: A prostaglandin reductase 1 isoform 1 that is encoded in the genome of rat.


name: PPA22_ARATH Purple acid phosphatase 22 (sprot)

description: A protein that is a translation product of the PAP22 gene in Arabidopsis thaliana.


name: proteasome subunit beta type-9 deaminated 2 (human)

description: A proteasome subunit beta type-9 (human) that has been deaminated on the residue at the position equivalent to Gln-130 of the amino acid sequence represented by UniProtKB:P28065-1. Example: UniProtKB:P28065-1, Gln-130, MOD:00685.


CYSTODYTIN F

An alkaloid that is an enamide obtained by the formal condensation of 3-methylbut-2-enoic acid with 6-(2-amino-1-methoxyethyl)-4H-pyrido[2,3,4-kl]acridin-4-one. It is isolated from the Okinawan marine tunicate Cystodytes dellechiajei and exhibits cytotoxicity against human epidermoid carcinoma KB cells.


name: microtubule-associated protein tau isoform Tau-F phosphorylated 6

description: A microtubule-associated protein tau isoform Tau-F phosphorylated form in which the phosphorylation occurs at the first and second serines and the first Thr in the motif SIDMVDSPQLAT. Example: UniProtKB:P10636-8, Ser-416/Ser-422, MOD:00046|Thr-427, MOD:00047.


name: microtubule-associated protein tau isoform Tau-F phosphorylated 6 (human)

description: A microtubule-associated protein tau isoform Tau-F phosphorylated 6 in human. UniProtKB:P10636-8, Ser-416/Ser-422, MOD:00046|Thr-427, MOD:00047.


FOCB_ECOLI Formate channel FocB (sprot)

A formate channel FocB that is encoded in the genome of Escherichia coli K-12.


polycythemia, non-human animal

category: biolink:Disease biolink:DiseaseOrPhenotypicFeature biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing

description: Polycythemia that occurs in non-human animals.


polycythemia, llama

description: Polycythemia that occurs in llama.


polycythemia, domestic cat

description: Polycythemia that occurs in domestic cat.


polycythemia, dog

description: Polycythemia that occurs in dog.


polycythemia, cattle

description: Polycythemia that occurs in cattle.


name: DLX2A_DANRE Homeobox protein Dlx2a (sprot)

description: A homeobox protein DLX-2 that is encoded in the genome of zebrafish.


name: breast cancer type 2 susceptibility protein sequence variant V323* (human)

description: A breast cancer type 2 susceptibility protein (human) that has has been truncated after the position equivalent to Lys-322 of the amino acid sequence represented by UniProtKB:P51587. UniProtKB:P51587, 1-322.


name: sodium/calcium exchanger 1 isoform r6 (rat)

description: A sodium/calcium exchanger 1 (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q01728-6.


name: cellular response to salicylic acid stimulus

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a salicylic acid stimulus.


name: prostaglandin E2 receptor EP3 subtype isoform hEP3B (human)

description: A prostaglandin E2 receptor EP3 subtype (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P43115-3.


prostanoid receptor

A rhodopsin-like G-protein coupled receptor that is a translation product of the human PTGDR, PTGDR2, PTGER1 to PTGER4, PTGFR, PTGIR, or TBXA2R genes, 1:1 orthologs thereof, or a semi-ortholog thereof. The active form binds prostanoids (prostaglandins and thromboxanes).


name: prostaglandin E2 receptor EP3 subtype isoform h12 (human)

description: A prostaglandin E2 receptor EP3 subtype (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P43115-12.


name: prostaglandin F2-alpha receptor isoform h7 (human)

description: A prostaglandin F2-alpha receptor (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P43088-7.


name: prostaglandin D2 receptor isoform h2 (human)

description: A prostaglandin D2 receptor (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q13258-2.


prostaglandin F2-alpha receptor

A prostanoid receptor that is a translation product of the human PTGFR gene or a 1:1 ortholog thereof. The preferred ligand is prostaglandin F2a. This receptor is particularly prevalent in the corpus luteum, but is expressed in other tissues also.


name: prostaglandin D2 receptor isoform h1 (human)

description: A prostaglandin D2 receptor (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q13258-1.


name: prostaglandin F2-alpha receptor isoform h4 (human)

description: A prostaglandin F2-alpha receptor (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P43088-4.


name: prostaglandin E2 receptor EP3 subtype isoform Alpha (mouse)

description: A prostaglandin E2 receptor EP3 subtype isoform 1 that is encoded in the genome of mouse.


name: PD2RL_RAT Prostaglandin D2 receptor-like (sprot)

description: A prostaglandin D2 receptor that is encoded in the genome of rat.


name: prostaglandin E2 receptor EP3 subtype isoform hEP3-IV (human)

description: A prostaglandin E2 receptor EP3 subtype (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P43115-9.


name: prostaglandin E2 receptor EP1 subtype isoform 1

description: A prostaglandin E2 receptor EP1 subtype that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P35375-1 or a 1:1 ortholog thereof.


name: A2TH15_CHICK Prostaglandin E2 receptor subtype 2 (trembl)

description: A prostaglandin E2 receptor EP2 subtype that is encoded in the genome of chicken.


name: prostaglandin F2-alpha receptor isoform 1 (rat)

description: A prostaglandin F2-alpha receptor isoform 1 that is encoded in the genome of rat.


name: prostaglandin E2 receptor EP3 subtype isoform hEP3E2 (human)

description: A prostaglandin E2 receptor EP3 subtype (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P43115-11.


name: prostaglandin E2 receptor EP3 subtype isoform hEP3E (human)

description: A prostaglandin E2 receptor EP3 subtype (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P43115-5.


name: PE2R4_HUMAN Prostaglandin E2 receptor EP4 subtype (sprot)

description: A prostaglandin E2 receptor EP4 subtype that is encoded in the genome of human.


name: prostaglandin E2 receptor EP3 subtype isoform 3

description: A prostaglandin E2 receptor EP3 subtype that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P30557-3 or a 1:1 ortholog thereof.


name: prostaglandin F2-alpha receptor isoform h3 (human)

description: A prostaglandin F2-alpha receptor (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P43088-3.


name: prostaglandin E2 receptor EP1 subtype isoform 1 (rat)

description: A prostaglandin E2 receptor EP1 subtype isoform 1 that is encoded in the genome of rat.


name: prostaglandin E2 receptor EP3 subtype isoform Alpha (rat)

description: A prostaglandin E2 receptor EP3 subtype isoform 1 that is encoded in the genome of rat.


name: prostacyclin receptor cysteinylated 2 (human)

description: A prostacyclin receptor (human) that has been cysteinylated on the residue at the position equivalent to Cys-211 of the amino acid sequence represented by UniProtKB:P43119. UniProtKB:P43119, Cys-211, MOD:00765.


name: PE2R2_MOUSE Prostaglandin E2 receptor EP2 subtype (sprot)

description: A prostaglandin E2 receptor EP2 subtype that is encoded in the genome of mouse.


name: PE2R2_RAT Prostaglandin E2 receptor EP2 subtype (sprot)

description: A prostaglandin E2 receptor EP2 subtype that is encoded in the genome of rat.


name: prostaglandin F2-alpha receptor isoform 1

description: A prostaglandin F2-alpha receptor that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P43117-1 or a 1:1 ortholog thereof.


name: PE2R4_RABIT Prostaglandin E2 receptor EP4 subtype (sprot)

description: A prostaglandin E2 receptor EP4 subtype that is encoded in the genome of rabbit.


name: prostaglandin E2 receptor EP1 subtype isoform 1 (mouse)

description: A prostaglandin E2 receptor EP1 subtype isoform 1 that is encoded in the genome of mouse.


prostaglandin D2 receptor

A prostanoid receptor that is a translation product of the human PTGDR gene or a 1:1 ortholog thereof. The preferred ligand is prostaglandin D2 (PGD2). This receptor is found mainly in blood platelets, vascular smooth muscle, and nervous tissue. It is the least upiquitous of the prostanoid receptors, almost always occurring in association with other prostanoid receptor types.


prostaglandin E2 receptor EP2 subtype

A prostanoid receptor that is a translation product of the human PTGER2 gene or a 1:1 ortholog thereof. The preferred ligand is prostaglandin E2 (PGE2). This receptor is expressed mediates various effects, including relaxation of vascular smooth muscles, nonacid secretion from epithelial cells, inhibition of mediator release from mast cells and basophils, and activation of sensory afferent nerves.


name: prostaglandin E2 receptor EP3 subtype isoform hEP3A (human)

description: A prostaglandin E2 receptor EP3 subtype (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P43115-1.


name: prostaglandin E2 receptor EP3 subtype isoform Beta (mouse)

description: A prostaglandin E2 receptor EP3 subtype isoform 2 that is encoded in the genome of mouse.


thromboxane A2 receptor

A prostanoid receptor that is a translation product of the human TBXA2R gene or a 1:1 ortholog thereof. The preferred ligand is thromboxane A2. This receptor is found mainly in vascular smooth muscle, where it mediates vasoconstriction, in platelets, where it mediates aggregation, and in airway smooth muscle.


name: thromboxane A2 receptor isoform h2 (human)

description: A thromboxane A2 receptor (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P21731-2.


prostaglandin D2 receptor DP2

A prostanoid receptor that is a translation product of the human PTGDR2 gene or a 1:1 ortholog thereof. The preferred ligand is 11-dehydro-thromboxane B2. This receptor is not closely related to the prostaglandin D2 receptor encoded by PGD2.


name: prostaglandin E2 receptor EP3 subtype isoform 1

description: A prostaglandin E2 receptor EP3 subtype that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P30557-1 or a 1:1 ortholog thereof.


name: thromboxane A2 receptor isoform 1 (mouse)

description: A thromboxane A2 receptor isoform 1 that is encoded in the genome of mouse.


prostaglandin E2 receptor EP1 subtype

A prostanoid receptor that is a translation product of the human PTGER1 gene or a 1:1 ortholog thereof. The preferred ligand is prostaglandin E2 (PGE2). This receptor has limited expression, although it is more evident in rodents than in other mammals.


prostacyclin receptor

A prostanoid receptor that is a translation product of the human PTGIR gene or a 1:1 ortholog thereof. The preferred ligand is prostacyclin (prostaglandin I2, PGI2). This receptor is widely distributed in blood platelets, vascular smooth muscle and nerve cells.


name: prostaglandin F2-alpha receptor isoform h1 (human)

description: A prostaglandin F2-alpha receptor (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P43088-1.


thromboxane A2 receptor isoform 1

A thromboxane A2 receptor that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P30987-1 or a 1:1 ortholog thereof.


name: prostaglandin E2 receptor EP3 subtype isoform 2

description: A prostaglandin E2 receptor EP3 subtype that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P30557-2 or a 1:1 ortholog thereof.


name: PE2R4_RAT Prostaglandin E2 receptor EP4 subtype (sprot)

description: A prostaglandin E2 receptor EP4 subtype that is encoded in the genome of rat.


name: prostaglandin E2 receptor EP3 subtype isoform hEP3-V (human)

description: A prostaglandin E2 receptor EP3 subtype (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P43115-10.


name: prostaglandin E2 receptor EP2 subtype methylated 1 (human)

description: A prostaglandin E2 receptor EP2 subtype (human) that has been methylated on the residue at the position equivalent to Cys-214 of the amino acid sequence represented by UniProtKB:P43116. UniProtKB:P43116, Cys-214, MOD:00660.


name: prostaglandin E2 receptor EP3 subtype isoform hEP3-III (human)

description: A prostaglandin E2 receptor EP3 subtype (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P43115-8.


name: prostaglandin F2-alpha receptor isoform h6 (human)

description: A prostaglandin F2-alpha receptor (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P43088-6.


name: prostaglandin E2 receptor EP3 subtype isoform hEP3C (human)

description: A prostaglandin E2 receptor EP3 subtype (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P43115-2.


prostaglandin E2 receptor EP3 subtype

A prostanoid receptor that is a translation product of the human PTGER3 gene or a 1:1 ortholog thereof. The preferred ligand is prostaglandin E2 (PGE2). This receptor is the most ubiquitous of the prostaglandin E2 receptors, mediating contraction of gastrointestinal, uterine, and vascular smooth muscle, inhibition of neurotransmitter release from autonomic nerves, inhibition of lipolysis in adipocytes, inhibition of acid secretion from gastric mucosa, and inhibition of water reabsorption in kidney.


name: prostaglandin E2 receptor EP1 subtype isoform r2 (rat)

description: A prostaglandin E2 receptor EP1 subtype (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P70597-2.


name: prostaglandin E2 receptor EP3 subtype isoform hEP3G (human)

description: A prostaglandin E2 receptor EP3 subtype (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P43115-7.


name: PE2R4_MOUSE Prostaglandin E2 receptor EP4 subtype (sprot)

description: A prostaglandin E2 receptor EP4 subtype that is encoded in the genome of mouse.


name: prostaglandin F2-alpha receptor isoform h5 (human)

description: A prostaglandin F2-alpha receptor (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P43088-5.


name: PE2R2_HUMAN Prostaglandin E2 receptor EP2 subtype (sprot)

description: A prostaglandin E2 receptor EP2 subtype that is encoded in the genome of human.


prostaglandin E2 receptor EP4 subtype

A prostanoid receptor that is a translation product of the human PTGER4 gene or a 1:1 ortholog thereof. The preferred ligand is prostaglandin E2. This receptor is not closely related to other prostaglandin E2 receptors.


name: prostaglandin E2 receptor EP3 subtype isoform hEP3D (human)

description: A prostaglandin E2 receptor EP3 subtype (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P43115-4.


name: prostacyclin receptor cysteinylated 1 (human)

description: A prostacyclin receptor (human) that has been cysteinylated on the residue at the position equivalent to Cys-118 of the amino acid sequence represented by UniProtKB:P43119. UniProtKB:P43119, Cys-118, MOD:00765.


name: PF2R_BOVIN Prostaglandin F2-alpha receptor (sprot)

description: A prostaglandin F2-alpha receptor that is encoded in the genome of cow.


name: thromboxane A2 receptor isoform h1 (human)

description: A thromboxane A2 receptor (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P21731-3.


name: prostaglandin E2 receptor EP4 subtype deaminated 1 (human)

description: A prostaglandin E2 receptor EP4 subtype (human) that has been deaminated on the residue at the position equivalent to Asn-177 of the amino acid sequence represented by UniProtKB:P35408. UniProtKB:P35408, Asn-177, MOD:00684.


name: prostaglandin E2 receptor EP3 subtype isoform hEP3F (human)

description: A prostaglandin E2 receptor EP3 subtype (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P43115-6.


name: prostaglandin F2-alpha receptor isoform h2 (human)

description: A prostaglandin F2-alpha receptor (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P43088-2.


name: prostaglandin E2 receptor EP3 subtype isoform Gamma (rat)

description: A prostaglandin E2 receptor EP3 subtype isoform 3 that is encoded in the genome of rat.


name: prostaglandin E2 receptor EP3 subtype isoform Beta (rat)

description: A prostaglandin E2 receptor EP3 subtype isoform 2 that is encoded in the genome of rat.


name: prostaglandin E2 receptor EP3 subtype isoform Gamma (mouse)

description: A prostaglandin E2 receptor EP3 subtype isoform 3 that is encoded in the genome of mouse.


name: prostaglandin F2-alpha receptor isoform 1 (mouse)

description: A prostaglandin F2-alpha receptor isoform 1 that is encoded in the genome of mouse.


thromboxane A2 receptor isoform 1 (rat)

A thromboxane A2 receptor isoform 1 that is encoded in the genome of rat.


name: HLA class I histocompatibility antigen, B alpha chain formylated 1 (human)

description: An HLA class I histocompatibility antigen, B alpha chain (human) that has been formylated on the residue at the position equivalent to Lys-267 of the amino acid sequence represented by UniProtKB:P01889. UniProtKB:P01889, Lys-267, MOD:00216.


name: alpha/beta hydrolase domain-containing protein 17A isoform 1 (human)

description: An alpha/beta hydrolase domain-containing protein 17A isoform 1 that is encoded in the genome of human.


name: alpha/beta hydrolase domain-containing protein 17A isoform 1

description: An alpha/beta hydrolase domain-containing protein 17A that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q96GS6-1 or a 1:1 ortholog thereof.


name: alpha/beta hydrolase domain-containing protein 17A isoform 1 (rat)

description: An alpha/beta hydrolase domain-containing protein 17A isoform 1 that is encoded in the genome of rat.


name: alpha/beta hydrolase domain-containing protein 17A isoform 1 (mouse)

description: An alpha/beta hydrolase domain-containing protein 17A isoform 1 that is encoded in the genome of mouse.


name: TCAF_DANRE TRPM8 channel-associated factor homolog (sprot)

description: A protein that is a translation product of the tcaf gene in zebrafish.


name: thrombocytopenia 12 with or without myopathy


name: transmembrane protease serine 3 cysteinylated 1 (human)

description: A transmembrane protease serine 3 (human) that has been cysteinylated on the residue at the position equivalent to Cys-129 of the amino acid sequence represented by UniProtKB:P57727-1. Example: UniProtKB:P57727-1, Cys-129, MOD:00765.


name: osmosensory signaling pathway via Sho1 osmosensor

category: biolink:Pathway biolink:OntologyClass biolink:BiologicalProcess biolink:Occurrent biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: The series of molecular signals generated in response to osmotic change, as mediated through a Sho1 osmosensor system.


osmosensory signaling pathway

description: The series of molecular signals initiated in response to osmotic change.


name: osmosensory signaling via phosphorelay pathway

description: The series of molecular signals generated in response to osmotic change, as mediated through a phosphorelay system. In S.cerevisiae, the osmosensor is the histidine kinase Sln1.


name: GRM7_MOUSE Metabotropic glutamate receptor 7 (sprot)

description: A metabotropic glutamate receptor 7 that is encoded in the genome of mouse.


name: metabotropic glutamate receptor 7 phosphorylated 1 (mouse)

description: A metabotropic glutamate receptor 7 phosphorylated 1 in mouse. UniProtKB:Q68ED2, Ser-900, MOD:00046.


name: metabotropic glutamate receptor 7 isoform 1 (mouse)

description: A metabotropic glutamate receptor 7 isoform 1 that is encoded in the genome of mouse.


upper aerodigestive tract neoplasm

description: Soft tissue tumors or cancer arising from the mucosal surfaces of the lip; oral cavity; pharynx; larynx; and cervical esophagus. Other sites included are the nose and paranasal sinuses; salivary glands; thyroid gland and parathyroid glands; and melanoma and non-melanoma skin cancers of the head and neck. (from Holland et al., Cancer Medicine, 4th ed, p1651)


name: Adenocarcinoma in multiple adenomatous polyps

description: Adenocarcinomas developing in gastrointestinal tract adenomas in patients with multiple adenomatous polyps.


name: Adenocarcinoma in adenomatous polyposis coli

description: Adenocarcinomas developing in colorectal adenomas in patients with a history of adenomatous polyposis coli. The mean age of development of adenocarcinoma is about 40 years.


name: coiled-coil domain-containing protein 17 isoform h3 (human)

description: A coiled-coil domain-containing protein 17 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q96LX7-2.


alcoholic psychosis

description: A group of mental disorders associated with organic brain damage and caused by poisoning from alcohol.


name: interleukin-13 receptor subunit alpha-2 isoform m2 (mouse)

description: An interleukin-13 receptor subunit alpha-2 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O88786-2.


name: interleukin-13 receptor subunit alpha-2 isoform m1 (mouse)

description: An interleukin-13 receptor subunit alpha-2 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O88786-1.


name: histone H3.3 type a trimethylated 1, acetylated tail form (Dictyostelium discoideum)

description: A histone H3.3 type a (Dictyostelium discoideum) that has been trimethylated at the position equivalent to Lys-5 of the amino acid sequence represented by UniProtKB:O15819, and that has been acetylated on one or more additional lysine residues within the N-terminal tail region. Note that the indicated residue is called Lys-4 in the literature, based on sequence numbering that accounts for a removed initiator methionine. UniProtKB:O15819, Lys-5, MOD:00083|MOD:00064.


childhood parosteal osteosarcoma

description: A low grade malignant bone-forming mesenchymal neoplasm arising from the surface of the bone. It occurs in childhood and usually affects the distal posterior femur, the proximal tibia, and proximal humerus. Painless swelling is the usual clinical sign. The prognosis is usually excellent.


peripheral osteosarcoma

description: A usually aggressive malignant bone-forming mesenchymal neoplasm arising from the surface of the bone.


high grade surface osteosarcoma

description: A usually aggressive high grade malignant bone-forming mesenchymal neoplasm arising from the surface of the bone.


Childhood Periosteal Osteosarcoma

description: A periosteal osteosarcoma occurring in childhood.


periosteal osteogenic sarcoma

description: An intermediate grade malignant bone-forming mesenchymal neoplasm with chondroblastic differentiation. It arises from the surface of the bone and affects the diaphysis or diaphyseal- metaphyseal portion of the long bones. A painless mass or swelling is the most common clinical sign. It is associated with a better prognosis than conventional osteosarcoma.


juxtacortical osteosarcoma

description: A low grade malignant bone-forming mesenchymal neoplasm arising from the surface of the bone. It usually affects the distal posterior femur, the proximal tibia, and proximal humerus. Painless swelling is the usual clinical sign. Most patients are young adults and the prognosis is usually excellent.


name: flap endonuclease 1 methylated 1 (human)

description: A flap endonuclease 1 (human) that has been methylated on the residue at the position equivalent to Met-67 of the amino acid sequence represented by UniProtKB:P39748-1. Example: UniProtKB:P39748-1, Met-67, MOD:00716.


name: homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein isoform 1 (mouse)

description: A homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein isoform 1 that is encoded in the genome of mouse.


name: homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein isoform 1

description: A homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q15011-1 or a 1:1 ortholog thereof.


name: homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein isoform 1 (human)

description: A homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein isoform 1 that is encoded in the genome of human.


N-acetyl-L-methionyl-L-isoleucine

A dipeptide obtained by formal condensation of the carboxy group of N-acetyl-L-methionine with the amino group of L-isoleucine.


name: ZFR_DANRE Zinc finger RNA-binding protein (sprot)

description: A zinc finger RNA-binding protein that is encoded in the genome of zebrafish.


name: TOG array regulator of axonemal microtubules protein 2 isoform h1 (human)

description: A TOG array regulator of axonemal microtubules protein 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q6ZUX3-1.


YIBA_ECOLI Protein YibA (sprot)

A protein YibA that is encoded in the genome of Escherichia coli K-12.


name: transmembrane protein 218 isoform 1 (mouse)

description: A transmembrane protein 218 isoform 1 that is encoded in the genome of mouse.


name: integrin alpha-PS1 isoform E (fruit fly)

description: An integrin alpha-PS1 (fruit fly) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q24247-5.


afadin isoform h4 (human)

An afadin (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P55196-4.


metallothionein-1L acetylated 1 (human)

A metallothionein-1L that is N-terminal Met acetylated in human. UniProtKB:Q93083, Met-1, MOD:00058.


A protein that is a translation product of the human MT1L gene or a 1:1 ortholog thereof.


MT1L_HUMAN Metallothionein-1L (sprot)

A metallothionein-1L that is encoded in the genome of human.


neuroligin-2 isoform 1 (mouse)

A neuroligin-2 isoform 1 that is encoded in the genome of mouse.


NLGN2_MOUSE Neuroligin-2 (sprot)

A neuroligin-2 that is encoded in the genome of mouse.


neuroligin-2 phosphorylated 1 (mouse)

A neuroligin-2 phosphorylated 1 in mouse. UniProtKB:Q69ZK9, Ser-714, MOD:00046.


hyccin 2 isoform 1 (human)

A hyccin 2 isoform 1 that is encoded in the genome of human.


name: sodium/myo-inositol cotransporter 2 isoform h1 (human)

description: A sodium/myo-inositol cotransporter 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8WWX8-1.


name: PDZ and LIM domain protein 3 isoform 2 (human)

description: A PDZ and LIM domain protein 3 isoform 2 that is encoded in the genome of human.


name: PDLI3_HUMAN PDZ and LIM domain protein 3 (sprot)

description: A PDZ and LIM domain protein 3 that is encoded in the genome of human.


name: PDZ and LIM domain protein 3 isoform h1 (human)

description: A PDZ and LIM domain protein 3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q53GG5-1.


name: PDZ and LIM domain protein 3 isoform h3 (human)

description: A PDZ and LIM domain protein 3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q53GG5-3.


name: SH2 domain-containing protein A isoform 2 (Arabidopsis thaliana)

description: An SH2 domain-containing protein A (Arabidopsis thaliana) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:B5X561-2.


name: fatty-acid-binding protein 2 isoform 4 (Arabidopsis thaliana)

description: A fatty-acid-binding protein 2 (Arabidopsis thaliana) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q84RK2-4.


protein AKNAD1 phosphorylated 1 (human)

A protein AKNAD1 (human) that has been phosphorylated on the residue at the position equivalent to Thr-165 of the amino acid sequence represented by UniProtKB:Q5T1N1-1. Example: UniProtKB:Q5T1N1-1, Thr-165, MOD:00047.


AKND1_HUMAN Protein AKNAD1 (sprot)

A protein AKNAD1 that is encoded in the genome of human.


protein AKNAD1 isoform h2 (human)

A protein AKNAD1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q5T1N1-2.


protein AKNAD1 isoform h4 (human)

A protein AKNAD1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q5T1N1-4.


protein AKNAD1 isoform h1 (human)

A protein AKNAD1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q5T1N1-1.


protein AKNAD1 isoform h3 (human)

A protein AKNAD1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q5T1N1-3.


neurofascin isoform 1 (rat)

A neurofascin isoform 9 that is encoded in the genome of rat.


neurofascin isoform 9

A neurofascin that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O94856-9 or a 1:1 ortholog thereof.


neurofascin isoform 1 (mouse)

A neurofascin isoform 9 that is encoded in the genome of mouse.


neurofascin isoform 9 (human)

A neurofascin isoform 9 that is encoded in the genome of human.


name: large ribosomal subunit protein uL2 isoform 1 (human)

description: A eukaryotic-type large ribosomal subunit protein uL2 isoform 1 that is encoded in the genome of human.


name: TGM3L_HUMAN Protein-glutamine gamma-glutamyltransferase 6 (sprot)

description: A protein-glutamine gamma-glutamyltransferase 6 that is encoded in the genome of human.


name: protein-glutamine gamma-glutamyltransferase 6 isoform h1 (human)

description: A protein-glutamine gamma-glutamyltransferase 6 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O95932-1.


name: protein-glutamine gamma-glutamyltransferase 6 isoform h2 (human)

description: A protein-glutamine gamma-glutamyltransferase 6 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O95932-2.


An amino disaccharide consisting of a 2-acetamido-2-deoxy-D-glucopyranose residue and a 2-acetamido-2-deoxy-D-galactopyranose residue joined in sequence by a (1->6) glycosidic bond.


SPITZ_DROME Protein spitz (sprot)

A protein that is a translation product of the spi gene in fruit fly.


name: CNX2_ARATH GTP 3',8-cyclase, mitochondrial (sprot)

description: A molybdenum cofactor biosynthesis protein 1 that is encoded in the genome of Arabidopsis thaliana.


name: GTP 3',8-cyclase, mitochondrial isoform 2 (Arabidopsis thaliana)

description: A GTP 3',8-cyclase, mitochondrial (Arabidopsis thaliana) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q39055-2.


name: GTP 3',8-cyclase, mitochondrial isoform 1 (Arabidopsis thaliana)

description: A GTP 3',8-cyclase, mitochondrial (Arabidopsis thaliana) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q39055-1.


copine-9 isoform h2 (human)

A copine-9 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8IYJ1-2.


name: guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2, initiator methionine removed form (human)

description: A guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 (human) that has had the initiator methionine removed. UniProtKB:P62879, 2-340.


cytidine deamination

description: The removal of amino group in the presence of water.


name: D-tagatose 6-phosphate catabolic process

description: The chemical reactions and pathways resulting in the breakdown of a D-tagatose 6-phosphate.


deoxycytidine catabolic process

description: The chemical reactions and pathways resulting in the breakdown of deoxycytidine, 2-deoxyribosylcytosine, one of the four major nucleosides of DNA.


chitobiose catabolic process

description: The chemical reactions and pathways resulting in the breakdown of any chitobiose, a family of compounds derived from chitin and based on the structure of D-glucosaminyl-(1->4)-D-glucosamine.


chitin catabolic process

description: The chemical reactions and pathways resulting in the breakdown of chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues.


N-acetylglucosamine catabolic process

description: The chemical reactions and pathways resulting in the breakdown of N-acetylglucosamine. The D isomer is a common structural unit of glycoproteins in plants, bacteria and animals; it is often the terminal sugar of an oligosaccharide group of a glycoprotein.


peptidoglycan catabolic process

description: The chemical reactions and pathways resulting in the breakdown of peptidoglycans, any of a class of glycoconjugates found in bacterial cell walls.


glycosylceramide catabolic process

description: The chemical reactions and pathways resulting in the breakdown of glycosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of a monosaccharide (or derivative) by a ceramide group.


deoxyribonucleoside catabolic process

description: The chemical reactions and pathways resulting in the breakdown of any one of a family of organic molecules consisting of a purine or pyrimidine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside).


glycopeptide catabolic process

description: The chemical reactions and pathways resulting in the breakdown of glycopeptides, a compound in which carbohydrate is covalently attached to an oligopeptide composed of residues of L and/or D-amino acids. The term usually denotes a product of proteolytic degradation of a glycoprotein but includes glycated peptide.


chondroitin sulfate catabolic process

description: The chemical reactions and pathways resulting in the breakdown of chondroitin sulfate, any member of a group of 10-60 kDa glycosaminoglycans, widely distributed in cartilage and other mammalian connective tissues, the repeat units of which consist of beta-(1,4)-linked D-glucuronyl beta-(1,3)-N-acetyl-D-galactosamine sulfate.


amino sugar catabolic process

description: The chemical reactions and pathways resulting in the breakdown of any amino sugar, sugars containing an amino group in place of a hydroxyl group.


butirosin catabolic process

description: The chemical reactions and pathways resulting in the breakdown of butirosin.


name: anthocyanin-containing compound catabolic process

description: The chemical reactions and pathways resulting in the breakdown of anthocyanins, any member of a group of intensely colored soluble glycosides of anthocyanidins.


proteoglycan catabolic process

description: The chemical reactions and pathways resulting in the breakdown of proteoglycans, any glycoprotein in which the carbohydrate units are glycosaminoglycans.


amino disaccharide catabolic process

description: The chemical reactions and pathways resulting in the breakdown of any amino disaccharide, a disaccharide having one or more substituted or unsubstituted amino groups in place of hydroxy groups at unspecified positions.


gentamycin catabolic process

description: The chemical reactions and pathways resulting in the breakdown of gentamycin.


paromomycin catabolic process

description: The chemical reactions and pathways resulting in the breakdown of paromomycin.


deoxyribose phosphate catabolic process

description: The chemical reactions and pathways resulting in the breakdown of deoxyribose phosphate, the phosphorylated sugar 2-deoxy-erythro-pentose.


description: The chemical reactions and pathways resulting in the breakdown of sophorosyloxydocosanoate, 13-sophorosyloxydocosanoate 6',6''-diacetate.


cytidine catabolic process

description: The chemical reactions and pathways resulting in the breakdown of cytidine, cytosine riboside, a widely distributed nucleoside.


name: pyrimidine deoxyribonucleoside catabolic process

description: The chemical reactions and pathways resulting in the breakdown of any one of a family of organic molecules consisting of a pyrimidine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside).


name: 2-deoxyribose 1-phosphate catabolic process

description: The chemical reactions and pathways resulting in the breakdown of deoxyribose 1-phosphate, the phosphorylated sugar 1-phospho-2-deoxyribose.


name: glucosamine-containing compound catabolic process

description: The chemical reactions and pathways resulting in the breakdown of glucosamine-containing compounds (glucosamines).


deoxyuridine catabolic process

description: The chemical reactions and pathways resulting in the breakdown of deoxyuridine, 2-deoxyribosyluracil, one of the four major nucleosides of DNA.


O-sialoglycoprotein catabolic process

description: The chemical reactions and pathways resulting in the breakdown of O-sialoglycoproteins, glycoproteins which contain sialic acid as one of their carbohydrates. They are often found on or in the cell or tissue membranes and participate in a variety of biological activities.


galactosylceramide catabolic process

description: The chemical reactions and pathways resulting in the breakdown of galactosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of galactose by a ceramide group.


name: pyrimidine ribonucleoside catabolic process

description: The chemical reactions and pathways resulting in the breakdown of any ribonucleoside, a nucleoside in which a pyrimidine base is linked to a ribose (beta-D-ribofuranose) molecule.


description: The chemical reactions and pathways resulting in the breakdown of poly-N-acetyllactosamine, a carbohydrate composed of N-acetyllactosamine repeats (Gal-beta-1,4-GlcNAc-beta-1,3)n.


purine nucleoside catabolic process

description: The chemical reactions and pathways resulting in the breakdown of purine nucleoside, one of a family of organic molecules consisting of a purine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside).


amylopectin catabolic process

description: The chemical reactions and pathways resulting in the breakdown of an amylopectin.


glucuronoside catabolic process

description: The chemical reactions and pathways resulting in the breakdown of glucuronosides, compound composed of a hydroxy compound linked to a glucuronate residue.


galactosaminoglycan catabolic process

description: The chemical reactions and pathways resulting in the breakdown of galactosaminoglycans, any of a group of polysaccharides that contain amino sugars derived from the galactose.


name: ubiquitin-dependent glycoprotein ERAD pathway

description: An ERAD pathway whereby endoplasmic reticulum (ER)-resident glycoproteins are targeted for degradation. Includes differential processing of the glycoprotein sugar chains, retrotranslocation to the cytosol and degradation by the ubiquitin-proteasome pathway. A glycoprotein is a compound in which a carbohydrate component is covalently bound to a protein component.


aminoglycan catabolic process

description: The chemical reactions and pathways resulting in the breakdown of aminoglycans, any polymer containing amino groups that consists of more than about 10 monosaccharide residues joined to each other by glycosidic linkages.


lincomycin catabolic process

description: The chemical reactions and pathways resulting in the breakdown of lincomycin.


ganglioside catabolic process

description: The chemical reactions and pathways resulting in the breakdown of ganglioside, a ceramide oligosaccharide carrying, in addition to other sugar residues, one or more sialic residues.


neomycin catabolic process

description: The chemical reactions and pathways resulting in the breakdown of neomycin.


S-glycoside catabolic process

description: The chemical reactions and pathways resulting in the breakdown of S-glycosides, any compound in which a glycosyl group has been substituted into a thiol group.


lipoteichoic acid catabolic process

description: The chemical reactions and pathways resulting in the breakdown of lipoteichoic acid, which is a major component of the cell wall of gram-positive bacteria and typically consists of a chain of glycerol-phosphate repeating units linked to a glycolipid anchor.


lipopolysaccharide catabolic process

description: The chemical reactions and pathways resulting in the breakdown of lipopolysaccharides, any of a group of related, structurally complex components of the outer membrane of Gram-negative bacteria.


kanamycin catabolic process

description: The chemical reactions and pathways resulting in the breakdown of kanamycin.


diacetylchitobiose catabolic process

description: The chemical reactions and pathways resulting in the breakdown of diacetylchitobiose into simpler products.


deoxyinosine catabolic process

description: The chemical reactions and pathways resulting in the breakdown of deoxyinosine, hypoxanthine deoxyriboside.


name: diacetylchitobiose catabolic process to glucosamine and acetate

description: The pathway resulting in the breakdown of diacetylchitobiose into simpler products, including glucosamine and glucosamine. The catabolism proceeds by the deacetylation of diacetylchitobiose, producing acetate and GlcN-GlcNAc; the latter is cleaved to produce glucosamine (GlcN) and N-acetylglucosamine (GlcNAc). The N-acetylglucosamine (GlcNAc) is then deacetylated to produce glucosamine (GlcN) and acetate.


name: aminoglycoside antibiotic catabolic process

description: The chemical reactions and pathways resulting in the breakdown of an aminoglycoside antibiotic, any member of a group of broad spectrum antibiotics, of similar toxicity and pharmacology, that contain an aminodeoxysugar, an amino- or guanidino-substituted inositol ring, and one or more residues of other sugars. The group includes streptomycin, neomycin, framycetin, kanamycin, paromomycin, and gentamicin.


name: ergosteryl 3-beta-D-glucoside catabolic process

description: The chemical reactions and pathways resulting in the breakdown of ergosteryl 3-beta-D-glucoside.


N-acetylmannosamine catabolic process

description: The chemical reactions and pathways resulting in the breakdown of N-acetylmannosamine, the acetylated derivative of mannosamine, 2-amino-2-deoxymannose.


glycosyl compound catabolic process

description: The chemical reactions and pathways resulting in the breakdown of glycosyl compound.


mannosamine catabolic process

description: The chemical reactions and pathways resulting in the breakdown of mannosomine, 2-amino-2-deoxymannose; the D-isomer is a constituent of neuraminic acids as well as mucolipids and mucoproteins.


mannoprotein catabolic process

description: The chemical reactions and pathways resulting in the breakdown of a mannoprotein, a protein that contains covalently bound mannose residues.


thymidine catabolic process

description: The chemical reactions and pathways resulting in the breakdown of thymidine, deoxyribosylthymine thymine 2-deoxyriboside, a deoxynucleoside very widely distributed but occurring almost entirely as phosphoric esters in deoxynucleotides and deoxyribonucleic acid, DNA.


nucleoside catabolic process

description: The chemical reactions and pathways resulting in the breakdown of any one of a family of organic molecules consisting of a purine or pyrimidine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside).


deoxyadenosine catabolic process

description: The chemical reactions and pathways resulting in the breakdown of deoxyadenosine, 2-deoxyribosyladenine, one of the four major nucleosides of DNA.


teichoic acid catabolic process

description: The chemical reactions and pathways resulting in the breakdown of teichoic acid, which is a major component of the cell wall of Gram-positive bacteria and typically consists of a polymer of glycerol-phosphate or ribitol-phosphate to which are attached glycosyl and D-alanyl ester residues.


ribonucleoside catabolic process

description: The chemical reactions and pathways resulting in the breakdown of any ribonucleoside, a nucleoside in which purine or pyrimidine base is linked to a ribose (beta-D-ribofuranose) molecule.


galactolipid catabolic process

description: The chemical reactions and pathways resulting in the breakdown of galactolipids, any glycolipid containing one of more residues of galactose and/or N-acetylgalactosamine.


glycoprotein catabolic process

description: The chemical reactions and pathways resulting in the breakdown of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide.


cyanogenic glycoside catabolic process

description: The chemical reactions and pathways resulting in the breakdown of cyanogenic glycosides, any glycoside containing a cyano group that is released as hydrocyanic acid on acid hydrolysis; such compounds occur in the kernels of various fruits.


heparin catabolic process

description: The chemical reactions and pathways resulting in the breakdown of heparin, any member of a group of glycosaminoglycans of average Mr (6000-20000), consisting predominantly of alternating alpha-(1->4)-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues.


name: purine deoxyribonucleoside catabolic process

description: The chemical reactions and pathways resulting in the breakdown of any one of a family of organic molecules consisting of a purine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside).


glycoside catabolic process

description: The chemical reactions and pathways resulting in the breakdown of glycosides, compounds in which a glycosyl group is substituted into a hydroxyl, thiol or selenol group in another compound.


deoxyguanosine catabolic process

description: The chemical reactions and pathways resulting in the breakdown of deoxyguanosine, a nucleoside consisting of the base guanine and the sugar deoxyribose.


lipooligosaccharide catabolic process

description: The chemical reactions and pathways resulting in the breakdown of lipooligosaccharide.


saponin catabolic process

description: The chemical reactions and pathways resulting in the breakdown of saponins, glycosides of plants in which the aglycan (sapogenin) group is a terpene or steroid and the sugar group is a glucose, a galactose, a pentose, a methylpentose or an oligosaccharide. Saponins are powerful surfactant agents and membrane active; they are, hence, toxic to animals on injection.


glucosylceramide catabolic process

description: The chemical reactions and pathways resulting in the breakdown of glucosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of glucose by a ceramide group.


glycolipid catabolic process

description: The chemical reactions and pathways resulting in the breakdown of glycolipid, a class of 1,2-di-O-acylglycerols joined at oxygen 3 by a glycosidic linkage to a carbohydrate part (usually a mono-, di- or tri-saccharide).


beta-glucoside catabolic process

description: The chemical reactions and pathways resulting in the breakdown of beta-glucoside.


uridine catabolic process

description: The chemical reactions and pathways resulting in the breakdown of uridine, uracil riboside, a ribonucleoside very widely distributed but occurring almost entirely as phosphoric esters in ribonucleotides and ribonucleic acids.


name: zeaxanthin bis(beta-D-glucoside) catabolic process

description: The chemical reactions and pathways resulting in the breakdown of zeaxanthin bis(beta-D-glucoside).


elastin catabolic process

description: The chemical reactions and pathways resulting in the breakdown of elastin. Elastin is a glycoprotein which is randomly coiled and crosslinked to form elastic fibers that are found in connective tissue.


pyridine nucleoside catabolic process

description: The chemical reactions and pathways resulting in the breakdown of any pyridine nucleoside, a nucleoside in which a pyridine base covalently bonded to a sugar, usually ribose.


queuosine catabolic process

description: The chemical reactions and pathways resulting in the breakdown of queuosines, any of a series of nucleosides found in tRNA and having an additional pentenyl ring added via an NH group to the methyl group of 7-methylguanosine. The pentenyl ring may carry other substituents.


fructosamine catabolic process

description: The chemical reactions and pathways resulting in the breakdown of fructosamine, a fructose molecule containing an amino group in place of a hydroxyl group.


ceruloplasmin deaminated 1 (human)

A ceruloplasmin (human) that has been deaminated on the residue at the position equivalent to Asn-696 of the amino acid sequence represented by UniProtKB:P00450. UniProtKB:P00450, Asn-696, MOD:00684.


name: Recurrent Childhood Gemistocytic Astrocytoma

description: The reemergence of gemistocytic astrocytoma in childhood after a period of remission.


Recurrent Astrocytic Tumor

description: The reemergence of an astrocytic tumor after a period of remission.


name: Recurrent Childhood Cerebellar Astrocytoma

description: Regrowth of benign and malignant childhood cerebellar astrocytomas that have previously been subjected to surgical resection and less frequently other forms of therapy such as radiation or chemotherapy.  Recurrence of benign tumors (e.g., (pilocytic astrocytoma) may respond to a second surgical procedure.


name: Recurrent Childhood Pleomorphic Xanthoastrocytoma

description: The reemergence of pleomorphic xanthoastrocytoma in childhood after a period of remission.


Recurrent MGMT-Methylated Glioblastoma

description: The reemergence of MGMT-methylated glioblastoma after a period of remission.


name: Recurrent Childhood Anaplastic Astrocytoma

description: The reemergence of anaplastic astrocytoma in childhood after a period of remission.


name: Recurrent Anaplastic Pleomorphic Xanthoastrocytoma

description: The reemergence of anaplastic pleomorphic xanthoastrocytoma after a period of remission.


name: Recurrent Childhood Visual Pathway Astrocytoma

description: The reemergence of visual pathway astrocytoma in childhood after a period of remission.


Recurrent Childhood Astrocytic Tumor

description: The reemergence of a childhood astrocytic tumor after a period of remission.


name: Recurrent Childhood Cerebral Astrocytoma

description: The reemergence of cerebral astrocytoma in childhood after a period of remission.