name: negative regulation of lymphocyte migration

description: Any process that stops, prevents or reduces the frequency, rate or extent of lymphocyte migration.


name: isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine

category: biolink:BiologicalProcess biolink:Occurrent biolink:OntologyClass biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: The formation of an isopeptide cross-link between peptidyl-lysine and peptidyl-glutamine to produce N6-(L-isoglutamyl)-L-lysine.


retinol metabolic process

description: The chemical reactions and pathways involving retinol, one of the three compounds that makes up vitamin A.


category: biolink:MolecularActivity biolink:Occurrent biolink:OntologyClass biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + beta-D-galactosyl-1,4-N-acetyl-D-glucosaminyl-R = UDP + N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-N-acetyl-D-glucosaminyl-R.


description: Catalysis of the reaction: S-adenosyl-L-methionine + adenine(645) in 25S rRNA = S-adenosyl-L-homocysteine + N(1)-methyladenine(645) in 25S rRNA.


name: isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway involved in terpenoid biosynthetic process

description: The chemical reactions and pathways resulting in the formation of isopentenyl diphosphate by the mevalonate-independent pathway that contributes to terpenoid biosynthesis. Isopentenyl diphosphate (IPP) is the fundamental unit in isoprenoid biosynthesis and is biosynthesized from pyruvate and glyceraldehyde 3-phosphate via intermediates, including 1-deoxy-D-xylulose 5-phosphate.


name: negative regulation of cellobiose metabolic process

description: Any process that stops, prevents or reduces the frequency, rate or extent of cellobiose metabolic process.


name: phosphotransferase activity, alcohol group as acceptor

description: Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to an alcohol group (acceptor).


name: negative regulation of carbohydrate metabolic process

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving carbohydrate.


name: porphyrin-containing compound biosynthetic process

description: The chemical reactions and pathways resulting in the formation of any member of a large group of derivatives or analogs of porphyrin. Porphyrin consists of a ring of four pyrrole nuclei linked each to the next at their alpha positions through a methine group.


name: negative regulation of blood pressure in another organism

description: A process by which one organism decreases the force with which blood travels through the circulatory system of another organism.


name: protein localization to mast cell secretory granule

description: A process in which a protein is transported to, or maintained in, a location within a secretory granule in a mast cell.


interleukin-8 production

description: The appearance of interleukin-8 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


vesicle fusion with Golgi apparatus

description: The joining of the lipid bilayer membrane around a vesicle to the lipid bilayer membrane around the Golgi.


name: circadian regulation of systemic arterial blood pressure by the suprachiasmatic nucleus

description: The process in which the suprachiasmatic nucleus modulates blood pressure at different values with a regularity of approximately 24 hours.


MHC class Ib receptor activity

description: Combining with an MHC class Ib protein complex and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. Class Ib here refers to non-classical class I molecules, such as those of the CD1 or HLA-E gene families.


name: regulation of interleukin-4-mediated signaling pathway

description: Any process that modulates the frequency, rate or extent of interleukin-4-mediated signaling pathway.


O-glycan processing, core 3

description: The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form the core 3 O-glycan structure, GlcNAc-beta-(1->3)-GalNAc.


protein depalmitoleylation

description: The removal of palmitoleyl group, a 16-carbon monounsaturated fatty acid (C16:1), from a lipoprotein.


non-lytic viral release

description: The exit of a viral particle from a host cell that does not involve cell lysis.


magnetoreception

description: The series of events required for an organism to receive a stimulus relating to a magnetic field, convert it to a molecular signal, and recognize and characterize the signal. Stimuli may be chemical, mechanical or electrical and interpreting these stimuli allows an organism to determine the orientation of a magnetic field. Magnetoreception also involves the perception of light; birds cannot orient without the presence of short wavelength (blue/green) light.


N-terminal peptidyl-serine methylation

description: The methylation of the N-terminal serine of proteins.


description: Catalysis of the reaction: coniferyl alcohol + UDP-D-glucose = coniferin + UDP.


name: organic hydroxy compound metabolic process

description: The chemical reactions and pathways involving organic hydroxy compound.


regulation of hemopoiesis

description: Any process that modulates the frequency, rate or extent of hemopoiesis.


name: cellular modified amino acid catabolic process

description: The chemical reactions and pathways resulting in the breakdown of compounds derived from amino acids, organic acids containing one or more amino substituents.


aldoxime metabolic process

description: The chemical reactions and pathways involving aldoximes, compounds derived by the reaction of an aldose with hydroxylamine, thus containing the aldoxime group -HC=NOH.


name: Golgi medial cisterna-derived vesicle fusion with Golgi cis cisterna membrane

description: The joining of the lipid bilayer membrane around a Golgi medial cisterna-derived vesicle to the lipid bilayer membrane around the Golgi cis cisterna. Such vesicles include COPI-coated transport vesicles involved in retrograde transport.


name: fast-twitch skeletal muscle fiber contraction

description: A process in which force is generated within fast-twitch skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The fast-twitch skeletal muscle is characterized by fast time parameters, high force development and fatiguability.


mitotic recombination

description: The exchange, reciprocal or nonreciprocal, of genetic material between one DNA molecule and a homologous DNA region that occurs during mitotic cell cycles.


name: pyruvate family amino acid catabolic process

description: The chemical reactions and pathways resulting in the breakdown of any amino acid that requires pyruvate for its synthesis, e.g. alanine.


name: negative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation

description: Any process that stops, prevents or reduces the frequency, rate or extent of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation.


name: evasion by virus of host dendritic cell activity

description: Any process by which a virus avoids the effects mediated by the host organism's dendritic cells.


tRNA guanine ribose methylation

description: The process whereby a guanosine residue in a tRNA is methylated on the 2'-hydroxyl group of the ribose moiety.


phospholipid dephosphorylation

description: The process of removing one or more phosphate groups from a phosphorylated lipid, any member of a group of substances soluble in lipid solvents but only sparingly soluble in aqueous solvents.


name: regulation of mitotic cytokinetic process

description: Any process that modulates the frequency, rate or extent of mitotic cytokinetic process.


astrocyte-dopaminergic neuron signaling

description: Cell-cell signaling that mediates the transfer of information from an astrocyte to a dopaminergic neuron.


interleukin-7 receptor activity

description: Combining with interleukin-7 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


RNA 7-methylguanosine cap binding

description: Binding to a 7-methylguanosine group added cotranscriptionally to the 5' end of RNA molecules transcribed by polymerase II.


macronucleus organization

description: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the macronucleus.


cellular response to lead ion

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lead ion stimulus.


negative regulation of cytokinesis

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the division of the cytoplasm of a cell, and its separation into two daughter cells.


netrin-activated signaling pathway

category: biolink:Pathway biolink:OntologyClass biolink:BiologicalProcess biolink:Occurrent biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: The series of molecular signals initiated by the binding of a netrin protein to its receptor on the surface of the target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. Netrins can act as chemoattractant signals for some cells and chemorepellent signals for others. Netrins also have roles outside of cell and axon guidance.


B cell cytokine production

description: Any process that contributes to cytokine production by a B cell.


name: porphyrin-containing compound catabolic process

description: The chemical reactions and pathways resulting in the breakdown of any member of a large group of derivatives or analogs of porphyrin. Porphyrin consists of a ring of four pyrrole nuclei linked each to the next at their alpha positions through a methine group.


viral DNA repair

description: The process of restoring viral DNA after damage or errors in replication.


circadian sleep/wake cycle, REM sleep

description: A stage in the circadian sleep cycle during which dreams occur and the body undergoes marked changes including rapid eye movement, loss of reflexes, and increased pulse rate and brain activity.


cellular response to morphine

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a morphine stimulus. Morphine is an opioid alkaloid, isolated from opium, with a complex ring structure.


name: negative regulation of cellular alcohol catabolic process

description: Any process that stops, prevents or reduces the frequency, rate or extent of cellular alcohol catabolic process.


clathrin coating of Golgi vesicle

description: The addition of clathrin and adaptor proteins to Golgi membranes during the formation of transport vesicles, forming a vesicle coat.


basement membrane organization

description: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the basement membrane.


protein-containing complex localization

description: A localization process that acts on a protein complex; the complex is transported to, or maintained in, a specific location.


pyripyropene A biosynthetic process

description: The chemical reactions and pathways resulting in the formation of pyripyropene A.


name: positive regulation of apoptotic signaling pathway

description: Any process that activates or increases the frequency, rate or extent of apoptotic signaling pathway.


name: telomere maintenance via telomere trimming

description: A process that contributes to the maintenance of proper telomeric length and structure via the activation of telomere shortening pathways that compensate telomerase-dependent excessive telomere elongation. Telomere attrition is mediated by a mechanism which involves the generation of single-stranded C-rich telomeric DNA, and the formation and removal of double-stranded telomeric circular DNA (T-circles). Telomere trimming is an independent pathway to recombination-mediated telomere elongation and the well-documented gradual telomere attrition that accompanies cellular replication.


name: positive regulation of cholesterol metabolic process

description: Any process that increases the rate, frequency, or extent of cholesterol metabolism, the chemical reactions and pathways involving cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.


response to stem cell factor

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stem cell factor (SCF) stimulus.


N-terminal peptidyl-valine acetylation

description: The acetylation of the N-terminal tyrosine of proteins to form the derivative N-acetyl-L-valine.


name: extracellular polysaccharide biosynthetic process

description: The chemical reactions and pathways resulting in the formation of polysaccharides used in extracellular structures.


name: mitochondrial double-strand break repair

description: The repair of double-strand breaks in mitochondrial DNA via homologous and nonhomologous mechanisms to reform a continuous DNA helix.


mannan metabolic process

description: The chemical reactions and pathways involving mannan, a group of polysaccharides containing a backbone composed of a polymer of D-mannose units.


name: GABA-gated chloride ion channel activity

description: Enables the transmembrane transfer of a chloride ion by a channel that opens when GABA has been bound by the channel complex or one of its constituent parts.


name: symbiont defense to host-produced phytoalexin

description: Any process in which a symbiont modulates the frequency, rate or extent of production of phytoalexins as part of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.


description: Catalysis of the reaction: adenosine(22) in tRNA + S-adenosyl-L-methionine = H+ + N(1)-methyladenosine(22) in tRNA + S-adenosyl-L-homocysteine.


name: response to G1 DNA damage checkpoint signaling

description: A process that occurs in response to signals generated as a result of G1/S transition DNA damage checkpoint signaling.


name: cellular response to polyamine macromolecule

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a polyamine macromolecule stimulus.


name: response to macrophage colony-stimulating factor

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a macrophage colony-stimulating factor stimulus.


protein localization to mitotic spindle

description: A process in which a protein is transported to, or maintained in, a location within a mitotic spindle.


deoxyguanosine biosynthetic process

description: The chemical reactions and pathways resulting in the formation of deoxyguanosine, a nucleoside consisting of the base guanine and the sugar deoxyribose.


description: Catalysis of the reaction: beta-D-galactosyl-1,3-(N-acetyl-D-glucosaminyl-1,6)-N-acetyl-D-galactosaminyl-R + UDP-N-acetyl-D-glucosamine = N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,3-(N-acetyl-beta-D-glucosaminyl-1,6)-N-acetyl-D-galactosaminyl-R + UDP.


somatostatin signaling pathway

description: A G protein-coupled receptor signaling pathway initiated by somatostatin binding to a somatostatin receptor (SSTR), and ending with the regulation of a downstream cellular process, e.g. transcription.


cellular response to D-galactosamine

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a D-galactosamine stimulus.


UDP-glucose metabolic process

description: The chemical reactions and pathways involving UDP-glucose, uridinediphosphoglucose, a substance composed of glucose in glycosidic linkage with uridine diphosphate.


single strand break repair

description: The repair of single strand breaks in DNA. Repair of such breaks is mediated by the same enzyme systems as are used in base excision repair.


interleukin-22 production

description: The appearance of interleukin-22 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


name: negative regulation of mast cell activation involved in immune response

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of mast cell activation as part of an immune response.


description: The carboxylation of the N-terminal methionine of proteins to form the derivative N-carboxy-L-methionine.


name: iodide transmembrane transporter activity

description: Enables the transfer of iodide ions from one side of a membrane to the other.


tetrachloroethylene catabolic process

description: The chemical reactions and pathways resulting in the breakdown of tetrachloroethylene, a derivative of ethene with the hydrogen atoms replaced by chlorines.


name: negative regulation of melanization defense response

description: Any process that reduces the rate or extent of the melanization defense response. This regulation is critical to limit melanization to the site of injury or infection.


name: aspartate family amino acid biosynthetic process

description: The chemical reactions and pathways resulting in the formation of amino acids of the aspartate family, comprising asparagine, aspartate, lysine, methionine and threonine.


name: Notch signaling pathway involved in regulation of secondary heart field cardioblast proliferation

description: The series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell contributing to the modulation of the frequency, rate or extent of cardioblast proliferation in the secondary heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.


name: translocation of peptides or proteins into symbiont

description: The directed movement of peptides or proteins produced by an organism to a location inside the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.


name: positive regulation of tongue muscle cell differentiation

description: Any process that activates or increases the frequency, rate or extent of tongue muscle cell differentiation.


cell cycle DNA replication termination

description: Any DNA replication termination that is involved in cell cycle DNA replication.


name: cellular response to parathyroid hormone stimulus

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a parathyroid hormone stimulus.


name: minus-end directed microfilament motor activity

description: A motor activity that generates movement along a microfilament towards the minus end, driven by ATP hydrolysis. The minus end of an actin filament is the end that does not preferentially add actin monomers.


CCL21-activated CCR7 signaling pathway

description: The series of molecular signals initiated by the binding of the C-C chemokine CCL21 to a C-C chemokine type 7 receptor (CCR7) on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.


name: hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

description: Catalysis of the hydrolysis of any acid anhydride which contains phosphorus.


mitochondrial mRNA 3'-end processing

description: Any process involved in forming the mature 3' end of an mRNA molecule that derives from the mitochondrial genome.


pentose biosynthetic process

description: The chemical reactions and pathways resulting in the formation of a pentose, any monosaccharide with a chain of five carbon atoms in the molecule.


name: central nervous system myelin maintenance

description: The process in which the structure and material content of mature central nervous system myelin is kept in a functional state.


stringent response

description: A specific global change in the metabolism of a bacterial cell (the downregulation of nucleic acid and protein synthesis, and the simultaneous upregulation of protein degradation and amino acid synthesis) as a result of starvation.


description: The chemical reactions and pathways involving phosphatidyl-N-monomethylethanolamine (PMME), a derivative of phosphatidylethanolamine with a methylated amine group.


name: peptide cross-linking via 2-(S-L-cysteinyl)-D-phenylalanine

description: The cross-linking of a cysteine residue to an L-phenylalanine residue to form 2-(S-L-cysteinyl)-D-phenylalanine.


D-arabitol metabolic process

description: The chemical reactions and pathways involving D-arabitol, the pentitol derived from arabinose or lyxose by reduction of the aldehyde group. The D enantiomer is present in lichens and mushrooms.


trisporic acid metabolic process

description: The chemical reactions and pathways involving trisporic acid, a carotenoic acid derivative used as a pheromone in some species of Zygomycota.


ATP-gated ion channel activity

description: Enables the transmembrane transfer of an ion by a channel that opens when ATP has been bound by the channel complex or one of its constituent parts.


name: negative regulation of sensory perception of pain in another organism

description: A process that negatively regulates the sensory perception of pain in a different organism.


name: Roundabout signaling pathway involved in muscle cell chemotaxis toward tendon cell

description: Any Roundabout signaling pathway that is involved in the directed movement of a muscle cell towards a tendon cell in response to an external stimulus.


name: positive regulation of nuclear cell cycle DNA replication

description: Any process that activates or increases the frequency, rate or extent of the DNA-dependent DNA replication that occurs in the nucleus of eukaryotic organisms as part of the cell cycle.


name: GPI anchor biosynthetic process via N-seryl-glycosylphosphatidylinositolethanolamine

description: The chemical reactions and pathways resulting in the formation of a C-terminal peptidyl-serine ethanolamide-linked glycosylphosphatidylinositol (GPI) anchor following hydrolysis of a seryl-peptide bond in the carboxy-terminal region of a membrane-associated protein.


glycol biosynthetic process

description: The chemical reactions and pathways resulting in the formation of glycol, a diol in which the two hydroxy groups are on different carbon atoms, usually but not necessarily adjacent.


protein localization to cytoskeleton

description: A process in which a protein is transported to, or maintained in, a location within the cytoskeleton.


name: viral double stranded DNA replication via reverse transcription

description: A DNA replication process that uses viral RNA as a template for RNA-dependent DNA polymerases (e.g. reverse transcriptase) that synthesize the new strands.


name: site-specific DNA replication termination

description: A DNA replication termination process that takes place at a specific termination site.


name: disruption of tissue in another organism

description: The disruption of a tissue of another organism, leading to damage or temporary subversion of that tissue.


name: adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway

description: An adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway initiated by glutamate binding to its receptor, and ending with the regulation of a downstream cellular process.


name: negative regulation of anti-Mullerian hormone signaling pathway

description: Any process that stops, prevents or reduces the frequency, rate or extent of anti-Mullerian hormone signaling pathway.


protein kinase C signaling

description: A series of reactions, mediated by the intracellular serine/threonine kinase protein kinase C, which occurs as a result of a single trigger reaction or compound.


name: regulation of mitotic DNA replication initiation

description: Any process that modulates the frequency, rate or extent of DNA replication initiation involved in mitotic DNA replication.


name: cellular organofluorine metabolic process

description: The chemical reactions and pathways involving organofluorine compounds, as carried out by individual cells.


lncRNA transcription

description: The transcription of lncRNAs, non-coding RNAs over 200 nucleotides in length, from a DNA template.


regulation of autophagosome size

description: Any process that modulates the size of the autophagosome.


folic acid catabolic process

description: The chemical reactions and pathways resulting in the breakdown of folic acid, pteroylglutamic acid.


valyl-tRNA aminoacylation

description: The process of coupling valine to valyl-tRNA, catalyzed by valyl-tRNA synthetase. The valyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2'-OH group of a valine-accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification.


D-glucuronate metabolic process

description: The chemical reactions and pathways involving D-glucuronate, the D-enantiomer of glucuronate.


degradation of host chromosome by virus

description: The catabolic breakdown of the DNA of a host chromosome by a virus. This occurs during infection of bacteria by some phages. It frees up a large pool of nucleoside 5'-triphophates for use in viral DNA synthesis.


name: positive regulation of anthocyanin catabolic process

description: Any process that activates or increases the frequency, rate or extent of anthocyanin catabolic process.


carbon tetrachloride catabolic process

description: The chemical reactions and pathways resulting in the breakdown of carbon tetrachloride, a toxic, carcinogenic compound which is used as a general solvent in industrial degreasing operations. It is also used as grain fumigant and a chemical intermediate in the production of refrigerants.


regulation of cellular pH

description: Any process involved in the maintenance of an internal equilibrium of hydrogen ions (protons) within a cell or between a cell and its external environment.


glutamate biosynthetic process

description: The chemical reactions and pathways resulting in the formation of glutamate, the anion of 2-aminopentanedioic acid.


name: negative regulation of granulocyte differentiation

description: Any process that stops, prevents, or reduces the frequency, rate or extent of granulocyte differentiation.


achromobactin biosynthetic process

description: The chemical reactions and pathways resulting in the formation of achromobactin, a citrate siderophore.


name: positive regulation of vascular endothelial growth factor receptor signaling pathway

description: Any process that activates or increases the frequency, rate or extent of vascular endothelial growth factor receptor signaling pathway activity.


4-toluenecarboxylate catabolic process

description: The chemical reactions and pathways resulting in the breakdown of 4-toluenecarboxylate, 4-methylbenzenecarboxylate, the anion of carboxylic acid attached to a methylbenzene molecule.


name: cellular response to luteinizing hormone stimulus

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a luteinizing hormone stimulus.


name: intrinsic apoptotic signaling pathway by p53 class mediator

description: The series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, and ends when the execution phase of apoptosis is triggered.


description: The chemical reactions and pathways involving a UDP-4-deoxy-4-formamido-beta-L-arabinopyranose.


name: regulation of intrinsic apoptotic signaling pathway by p53 class mediator

description: Any process that modulates the frequency, rate or extent of intrinsic apoptotic signaling pathway by p53 class mediator.


cell activation

description: A multicellular organismal process by which exposure to an activating factor such as a cellular or soluble ligand results in a change in the morphology or behavior of a cell.


description: The chemical reactions and pathways involving octamethylcyclotetrasiloxane, a cyclic silicone-oxygen ring compound with two methyl groups attached to each silicone atom.


phthalate metabolic process

description: The chemical reactions and pathways involving phthalate, the anion of phthalic acid. Phthalic acid diesters are used industrially in the production of a variety of household and consumer goods including plastic polymers, lubricating oils, and carriers for perfumes in cosmetics, while phthalic acid itself is used industrially as a plasticizer. Terephthalate is used in the synthesis of polyethylene terephthalate (polyethene terephthlate, abbreviated PET or PETE), a plastic polymer with many commercial uses.


name: response to mitotic DNA replication checkpoint signaling

description: A process that occurs in response to signals generated as a result of mitotic DNA replication checkpoint signaling.


5'-3' DNA helicase activity

description: Unwinding a DNA helix in the 5' to 3' direction, driven by ATP hydrolysis.


cellular response to cadmium ion

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cadmium (Cd) ion stimulus.


segmentation

description: The regionalization process that divides an organism or part of an organism into a series of semi-repetitive parts, or segments, often arranged along a longitudinal axis.


regulation of DNA ligase activity

description: Any process that modulates the frequency, rate or extent of DNA ligase activity.


glycogenin glucosyltransferase activity

description: Catalysis of the reaction: UDP-glucose + glycogenin = UDP + glucosylglycogenin.


name: cellular response to oxygen-glucose deprivation

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the deprivation of oxygen and glucose.


diacylglycerol acyl-chain remodeling

description: Remodeling the acyl chains of diacylglycerol, through sequential deacylation and re-acylation reactions, to generate diacylglycerol containing different types of fatty acid acyl chains.


name: internal mRNA (guanine-N7-)-methyltransferase activity

description: Catalysis of the reaction: a guanosine in mRNA + S-adenosyl-L-methionine = an N(7)-methylguanosine in mRNA + S-adenosyl-L-homocysteine.


description: Catalysis of the reaction: methylazoxymethanol + UDP-D-glucose = H+ + cycasin + UDP.


hypoxanthine metabolic process

description: The chemical reactions and pathways involving hypoxanthine, 6-hydroxy purine, an intermediate in the degradation of adenylate. Its ribonucleoside is known as inosine and its ribonucleotide as inosinate.


single-stranded DNA helicase activity

description: Catalysis of the reaction: ATP + H2O = ADP + phosphate, in the presence of single-stranded DNA; drives the unwinding of a DNA helix.


nopaline catabolic process

description: The chemical reactions and pathways resulting in the breakdown of nopaline (N-(I-carboxy-4-guanidinobutyl)glutamic acid), a rare amino-acid derivative.


name: nitric oxide mediated signal transduction

description: An intracellular signaling cassette that starts with production of nitric oxide, detection by receptors/sensors for nitric oxide (such as soluble guanylyl cyclase/sGC) and ends with the activation of downstream effectors that further transmit the signal within the cell. Nitric oxide transmits its downstream effects through either cyclic GMP (cGMP)-dependent or independent mechanisms.


ligase activity

description: Catalysis of the joining of two molecules, or two groups within a single molecule, using the energy from the hydrolysis of ATP, a similar triphosphate, or a pH gradient.


name: viral budding from inner nuclear membrane

description: The envelopment of a virus, in which the nucleocapsid evaginates from the host inner nuclear membrane system into the perinuclear space, thus acquiring a membrane envelope.


deoxyuridine metabolic process

description: The chemical reactions and pathways involving deoxyuridine, 2-deoxyribosyluracil, one of the four major nucleosides of DNA.


name: regulation of prolactin signaling pathway

description: Any process that modulates the frequency, rate or extent of prolactin signaling pathway.


response to chemokine

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemokine stimulus.


name: isoflavonoid phytoalexin biosynthetic process

description: The chemical reactions and pathways resulting in the formation of isoflavonoid phytoalexins, a group of water-soluble phenolic derivatives isomeric with flavonoids that possess antibiotic activity and are produced by plant tissues in response to infection.


L-fuculokinase activity

description: Catalysis of the reaction: L-fuculose + ATP = L-fuculose 1-phosphate + ADP + 2 H+.


name: negative regulation of plant-type cell wall cellulose catabolic process

description: Any process that stops, prevents or reduces the frequency, rate or extent of plant-type cell wall cellulose catabolic process.


non-photoreactive DNA repair

description: A DNA repair process that is involved in repairing UV-induced DNA damage under non-photoreactivating conditions. The mechanism by which this repair process operates has not yet been completely elucidated.


1,3-dichloropropene metabolic process

description: The chemical reactions and pathways involving members of the 1,3-dichloropropene family, which includes cis- and trans-1,3-dichloropropene. The 1,3-dichloropropenes are chlorinated hydrocarbons and the major active ingredients of commercial products for control of plant-parasitic nematodes.


response to organic cyclic compound

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus.


maturation of LSU-rRNA

description: Any process involved in the maturation of a precursor Large SubUnit (LSU) ribosomal RNA (rRNA) molecule into a mature LSU-rRNA molecule.


orcinol catabolic process

description: The chemical reactions and pathways resulting in the breakdown of orcinol (5-methyl-1,3-benzenediol), an aromatic compound derived from the fermentation of lichen and synthesized by some higher plants.


butyryl-CoA catabolic process

description: The chemical reactions a resulting in the resulting in the breakdown of butyryl-CoA.


name: positive regulation of cellulose catabolic process

description: Any process that activates or increases the frequency, rate or extent of cellulose catabolic process.


benzoate catabolic process

description: The chemical reactions and pathways resulting in the breakdown of benzoate, the anion of benzoic acid (benzenecarboxylic acid), a fungistatic compound widely used as a food preservative; it is conjugated to glycine in the liver and excreted as hippuric acid.


name: regulation of transcription, start site selection

description: Any process that modulates the frequency, rate or extent of the synthesis of either RNA on a template of DNA or DNA on a template of RNA by a mechanism that selects the start site along that template.


astaxanthin catabolic process

description: The chemical reactions and pathways resulting in the breakdown of astaxanthin.


name: regulation of vascular associated smooth muscle cell apoptotic process

description: Any process that modulates the frequency, rate or extent of vascular associated smooth muscle cell apoptotic process.


name: positive regulation of response to biotic stimulus

description: Any process that activates or increases the frequency, rate, or extent of a response to biotic stimulus.


cellular response to peptidoglycan

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptidoglycan stimulus. Peptidoglycan is a bacterial cell wall macromolecule.


catalytic activity, acting on a rRNA

description: Catalytic activity that acts to modify a ribosomal RNA.


pyrimidine-containing compound salvage

description: Any process that generates a pyrimidine-containing compound, a nucleobase, nucleoside, nucleotide or nucleic acid that contains a pyrimidine base, from derivatives of them without de novo synthesis.


dehydroaustinol catabolic process

description: The chemical reactions and pathways resulting in the breakdown of dehydroaustinol.


isoquinoline alkaloid catabolic process

description: The chemical reactions and pathways resulting in the breakdown of isoquinoline alkaloids, alkaloid compounds that contain bicyclic N-containing aromatic rings and are derived from a 3,4-dihydroxytyramine (dopamine) precursor that undergoes a Schiff base addition with aldehydes of different origin.


primary alcohol biosynthetic process

description: The chemical reactions and pathways resulting in the formation of primary alcohols. A primary alcohol is any alcohol in which a hydroxy group, -OH, is attached to a saturated carbon atom which has either three hydrogen atoms attached to it or only one other carbon atom and two hydrogen atoms attached to it.


CAT tailing

description: The C-terminal elongation of 60S-anchored stalled nascent polypeptide chains with untemplated alanine and threonine tails (CAT tails). CAT tails participate in the recognition of stalled nascent chains by the ribosome quality control system.


description: The series of molecular signals initiated by interleukin-4 binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.


ER overload response

description: The series of molecular signals initiated by the accumulation of normal or misfolded proteins in the endoplasmic reticulum and leading to activation of transcription by NF-kappaB.


response to aluminum ion

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aluminum ion stimulus.


RNA secondary structure unwinding

description: The process in which a secondary structure of RNA are broken or 'melted'.


fertilization

description: The union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy).


cyanuric acid catabolic process

description: The chemical reactions and pathways resulting in the breakdown of cyanuric acid, a potential degradation product of triazine herbicides.


name: endocannabinoid signaling pathway involved in retrograde trans-synaptic signaling

description: Any endocannabinoid signaling pathway that is involved in retrograde trans-synaptic signaling by endocannabinoid.


name: nucleoside monophosphate catabolic process

description: The chemical reactions and pathways resulting in the breakdown of a nucleoside monophosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with phosphate on the sugar.


name: positive regulation of abscisic acid-activated signaling pathway

description: Any process that activates or increases the frequency, rate or extent of abscisic acid (ABA) signaling.


cellular hyperosmotic response

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a hyperosmotic environment, i.e. an environment with a higher concentration of solutes than the organism or cell.


description: The chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds.


name: tolerance induction dependent upon immune response

description: Tolerance induction dependent upon an immune response, typically a response by a mature T or B cell in the periphery resulting tolerance towards an antigen via induction of anergy, cellular deletion, or regulatory T cell activation.


name: symbiont-mediated disruption of host focal adhesion

description: A process in which a symbiont alters or subverts focal adhesion in its host. The host is defined as the larger of the organisms involved in a symbiotic interaction.


mitomycin C biosynthetic process

description: The chemical reactions and pathways resulting in the formation of mitomycin C.


name: establishment of mitochondrion localization, microtubule-mediated

description: The directed movement of the mitochondrion to a specific location, by a process involving microtubules.


adhesion of symbiont spore to host

description: The attachment of a spore of the symbiont to its host via adhesion molecules, general stickiness etc. The host is defined as the larger of the organisms involved in a symbiotic interaction.


description: Catalysis of the reaction: 5alpha-dihydrotestosterone + NAD+ = 5alpha-androstane-3,17-dione + NADH.


name: ionotropic bitter taste receptor activity

description: Enables the transmembrane transfer of an ion by a channel that opens when a specific bitter compound has been bound by the channel complex or one of its constituent parts.


colon smooth muscle contraction

description: A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry of the large intestine, exclusive of the rectum. The colon is that part of the large intestine that connects the small intestine to the rectum.


name: positive regulation of smoothened signaling pathway

description: Any process that activates or increases the frequency, rate or extent of smoothened signaling.


orlandin catabolic process

description: The chemical reactions and pathways resulting in the breakdown of orlandin.


name: positive regulation of dendritic cell apoptotic process

description: Any process that activates or increases the frequency, rate or extent of dendritic cell apoptotic process.


isopentenyl adenine metabolic process

description: The chemical reactions and pathways involving the cytokinin 6-isopentenyladenine.


polyacyltrehalose metabolic process

description: The chemical reactions and pathways involving polyacyltrehalose, a pentaacylated, trehalose-based glycolipid.


name: cellular response to triacyl bacterial lipopeptide

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a triacylated bacterial lipopeptide stimulus.


name: negative regulation of phytoalexin metabolic process

description: Any process that stops, prevents, or reduces the frequency, rate or extent of phytoalexin metabolism, the chemical reactions and pathways involving phytoalexins.


dGDP biosynthetic process

description: The chemical reactions and pathways resulting in the formation of dGDP, deoxyguanosine diphosphate, (2'-deoxyguanosine 5'-diphosphate).


juvenile hormone catabolic process

description: The chemical reactions and pathways resulting in the breakdown of juvenile hormones, the three sesquiterpenoid derivatives that function to maintain the larval state of insects at molting and that may be required for other processes, e.g. oogenesis.


description: The series of molecular signals initiated by interleukin-34 binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.


description: The chemical reactions and pathways involving 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one, also known as DIF-1, differentiation-inducing factor-1. DIF-1 is a secreted chlorinated molecule that controls cell fate during development of Dictyostelium cells.


regulation of starch metabolic process

description: Any process that modulates the frequency, rate or extent of starch metabolic process.


name: cellular response to brassinosteroid stimulus

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a brassinosteroid stimulus.


cellular response to sterol depletion

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating deprivation of sterols. Sterols are a group of steroids characterized by the presence of one or more hydroxyl groups and a hydrocarbon side-chain in the molecule.


name: spindle pole body-led chromosome movement during mitotic interphase

description: A microtubule-based process in which chromosomes migrate as a result of rapid spindle pole body (SPB) and centrosome oscillations during mitotic interphase.


description: Catalysis of the reaction: S-adenosyl-L-methionine + calmodulin L-lysine = S-adenosyl-L-homocysteine + calmodulin N6-methyl-L-lysine.


peptidyl-leucine modification

description: The modification of peptidyl-leucine.


name: fibroblast growth factor receptor signaling pathway involved in forebrain neuroblast division

description: The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands that contributes to the self renewal of neuroblasts in the forebrain.


pronephros development

description: The process whose specific outcome is the progression of the pronephros over time, from its formation to the mature structure. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life.


boss receptor activity

description: Combining with a protein bride of sevenless (boss) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP + a protein-L-tyrosine = ADP + a protein-L-tyrosine phosphate.


name: negative regulation of smoothened signaling pathway

description: Any process that stops, prevents, or reduces the frequency, rate or extent of smoothened signaling.


xylogalacturonan metabolic process

description: The chemical reactions and pathways involving xylogalacturonan, a pectin characterized by a backbone of alpha-(1->4)-linked D-galacturonic acid residues substituted on C-3 with beta-D-xylopyranose residues.


name: guanosine tetraphosphate metabolic process

description: The chemical reactions and pathways involving guanine tetraphosphate (5'-ppGpp-3'), a derivative of guanine riboside with four phosphates.


name: proton motive force-driven ATP synthesis

description: The transport of protons across a membrane to generate an electrochemical gradient (proton-motive force) that powers ATP synthesis.


tRNA wobble uridine modification

description: The process in which a uridine in position 34 of a tRNA is post-transcriptionally modified.


cellular response to Aroclor 1254

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an Aroclor 1254 stimulus.


phosphorelay signal transduction system

description: A conserved series of molecular signals found in prokaryotes and eukaryotes; involves autophosphorylation of a histidine kinase and the transfer of the phosphate group to an aspartate that then acts as a phospho-donor to response regulator proteins.


D-serine catabolic process

description: The chemical reactions and pathways resulting in the breakdown of D-serine, the D-enantiomer of serine, i.e. (2S)-2-amino-3-hydroxypropanoic acid.


name: positive regulation of semaphorin-plexin signaling pathway involved in outflow tract morphogenesis

description: Any process that activates or increases the frequency, rate or extent of semaphorin-plexin signaling pathway involved in outflow tract morphogenesis.


maintenance of cell number

description: Any process by which the numbers of cells of a particular type or in a tissue are maintained.


name: negative regulation of thioredoxin peroxidase activity by peptidyl-threonine phosphorylation

description: A peptidyl-threonine phosphorylation that results in negative regulation of thioredoxin peroxidase activity.


beta2-adrenergic receptor activity

description: Combining with epinephrine or norepinephrine to initiate a change in cell activity via activation of a G protein, with pharmacological characteristics of beta2-adrenergic receptors.


description: Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N6-methyladenine.


name: tryptophan catabolic process to kynurenine

description: The chemical reactions and pathways resulting in the breakdown of tryptophan into other compounds, including kynurenine.


name: low-density lipoprotein particle disassembly involved in cholesterol transport

description: The disassembly into constituent parts of the low-density lipoprotein particle in the lysosome that contributes to cholesterol transport.


cyclopentanol biosynthetic process

description: The chemical reactions and pathways resulting in the formation of cyclopentanol.


name: cellular response to ciliary neurotrophic factor

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ciliary neurotrophic factor stimulus.


name: positive regulation of non-canonical Wnt signaling pathway

description: Any process that activates or increases the frequency, rate or extent of non-canonical Wnt-activated signaling pathway.


glucuronoside biosynthetic process

description: The chemical reactions and pathways resulting in the formation of glucuronosides, compound composed of a hydroxy compound linked to a glucuronate residue.


name: regulation of snRNA pseudouridine synthesis

description: Any process that modulates the frequency, rate or extent of snRNA pseudouridine synthesis.


fat-soluble vitamin catabolic process

description: The chemical reactions and pathways resulting in the breakdown of any of a diverse group of vitamins that are soluble in organic solvents and relatively insoluble in water.


description: Catalysis of the reaction: beta-D-galactosyl-(1,4)-beta-N-acetyl-D-glucosaminyl-R + UDP-galactose = alpha-D-galactosyl-(1,3)-beta-D-galactosyl-(1,4)-beta-N-acetyl-D-glucosaminyl-R + UDP.


stress granule disassembly

description: The disaggregation of a stress granule into its constituent protein and RNA parts.


name: apoptotic process involved in atrial ventricular junction remodeling

description: Any apoptotic process that contributes to the reorganization of tissue resulting in the maturation of the atrial ventricular junction.


name: positive regulation of neutrophil mediated killing of bacterium

description: Any process that increases the frequency, rate or extent of the directed killing of a bacterium by a neutrophil.


3-methylquinoline catabolic process

description: The chemical reactions and pathways resulting in the breakdown of 3-methylquinoline, C10H9N, an aromatic compound composed of a benzene ring and a heterocyclic N-containing ring.


name: steroid receptor RNA activator RNA binding

description: Binding to a steroid receptor RNA activator RNA (SRA). SRA enhances steroid hormone receptor transcriptional activity as an RNA transcript by an indirect mechanism that does not involve SRA-steroid receptor binding.


name: negative regulation of exit from meiosis

description: Any process that stops, prevents or reduces the frequency, rate or extent of exit from meiosis.


glucosinolate catabolic process

description: The chemical reactions and pathways resulting in the breakdown of glucosinolates, substituted thioglucosides found in rapeseed products and related cruciferae.


fructosamine metabolic process

description: The chemical reactions and pathways involving fructosamine, a fructose molecule containing an amino group in place of a hydroxyl group.


name: beta-alanine biosynthetic process via 1,3 diaminopropane

description: The chemical reactions and pathways resulting in the formation of beta-alanine via the intermediate 1,3 diaminopropane.


name: N-terminal peptidyl-aspartic acid acetylation

description: The acetylation of the N-terminal aspartic acid of proteins; catalyzed by aspartate N-acetyltransferase.


dGDP metabolic process

description: The chemical reactions and pathways involving dGDP, deoxyguanosine diphosphate, (2'-deoxyguanosine 5'-diphosphate).


glycosyltransferase activity

description: Catalysis of the transfer of a glycosyl group from one compound (donor) to another (acceptor).


name: mitochondrial outer membrane permeabilization involved in programmed cell death

description: The process by which the mitochondrial outer membrane becomes permeable to the passing of proteins and other molecules from the intermembrane space to the cytosol as part of a programmed cell death process.


name: acetate ester metabolic process involved in fermentation

description: Any acetate ester metabolic process that is involved in fermentation.


arabinan biosynthetic process

description: The chemical reactions and pathways resulting in the formation of arabinan, a polysaccharide composed of arabinose residues.


name: organic heteropentacyclic compound biosynthetic process

description: The chemical reactions and pathways resulting in the formation of organic heteropentacyclic compound.


name: mitotic spindle microtubule depolymerization

description: The removal of tubulin heterodimers from one or both ends of a microtubule that is part of the mitotic spindle.


ribitol catabolic process

description: The chemical reactions and pathways resulting in the breakdown of ribitol, a pentitol derived formally by reduction of the -CHO group of either D- or L-ribose.


name: lactate fermentation to propionate and acetate

description: The anaerobic enzymatic conversion of lactate to propionate, concomitant with the oxidation of lactate to acetate and CO2 and yielding energy in the form of adenosine triphosphate (ATP).


regulation of hydrolase activity

description: Any process that modulates the frequency, rate or extent of hydrolase activity, the catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3.


name: positive regulation of meiotic sister chromatid arm separation

description: Any process that increases the rate or extent of meiotic sister chromatid arm separation, the cell cycle process in which sister chromatid arms are physically detached from each other during meiosis.


colon epithelial cell chemotaxis

description: The directed movement of a colon epithelial cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).


mannosylglycerate metabolic process

description: The chemical reactions and pathways involving mannosylglycerate, a very common compatible solute in thermophilic and hyperthermophilic organisms.


name: modulation by symbiont of host cholinergic synaptic transmission

description: Any process in which a symbiont organism modulates the frequency, rate or extent of cholinergic synaptic transmission, communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse via the neurotransmitter choline, in its host organism.


name: positive regulation of galactomannan catabolic process

description: Any process that activates or increases the frequency, rate or extent of galactomannan catabolic process.


name: voltage-gated sodium channel activity involved in Purkinje myocyte action potential

description: Enables the transmembrane transfer of a sodium ion by a voltage-gated channel through the plasma membrane of a Purkinje myocyte contributing to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.


killing of cells of another organism

description: Any process in an organism that results in the killing of cells of another organism, including in some cases the death of the other organism. Killing here refers to the induction of death in one cell by another cell, not cell-autonomous death due to internal or other environmental conditions.


phylloquinone metabolic process

description: The chemical reactions and pathways involving phylloquinone, a quinone-derived compound synthesized by green plants. Phylloquinone has vitamin K activity and is known as vitamin K1.


enkephalin processing

description: The formation of mature enkephalin, a pentapeptide hormone involved in regulating pain and nociception in the body by proteolytic processing of enkephalin propeptide.


germinal center formation

description: The process in which germinal centers form. A germinal center is a specialized microenvironment formed when activated B cells enter lymphoid follicles. Germinal centers are the foci for B cell proliferation and somatic hypermutation.


name: amyloid precursor protein biosynthetic process

description: The chemical reactions and pathways resulting in the formation of amyloid precursor protein (APP), the precursor of amyloid-beta, a glycoprotein associated with Alzheimer's disease.


description: The chemical reactions and pathways involving (25S)-Delta(4)-dafachronate.


Group III intron splicing

description: The splicing of Group III introns. This occurs by a ribozymic mechanism where the intron sequence forms a distinct 3D structure, characteristic of Group III introns, that is involved in catalyzing the splicing reactions, though protein factors are also required in vivo. Splicing occurs by a series of two transesterification reactions begun by a bulged adenosine residue within the intron sequence as the initiating nucleophile. The intron is excised as a lariat. Though very similar in structure and mechanism to Group II introns, Group III introns are smaller and more streamlined and the splice site consensus sequences are not as well conserved.


description: Catalysis of the reaction: guanosine(10) in tRNA + 2 S-adenosyl-L-methionine = 2 H+ + N(2)-dimethylguanosine(10) in tRNA + 2 S-adenosyl-L-homocysteine.


semaphorin-plexin signaling pathway

description: The series of molecular signals generated as a consequence of a semaphorin receptor (composed of a plexin and a neurophilin) binding to a semaphorin ligand.


lycopene catabolic process

description: The chemical reactions and pathways resulting in the breakdown of lycopene.


regulation of localization

description: Any process that modulates the frequency, rate or extent of any process in which a cell, a substance, or a cellular entity is transported to, or maintained in, a specific location.


name: negative regulation of cordyol C biosynthetic process

description: Any process that stops, prevents or reduces the frequency, rate or extent of cordyol C biosynthetic process.


description: The chemical reactions and pathways resulting in the breakdown of S,S-dimethyl-beta-propiothetin.


name: chromosomal DNA methylation maintenance following DNA replication

description: The process that maintains methylated cytosine in newly synthesized DNA following DNA replication. After the establishment of novel DNA methylation marks, the newly created patterns must be faithfully transmitted by maintenance DNA methyltransferases during cell division.


name: negative regulation of ERBB3 signaling pathway

description: Any process that stops, prevents or reduces the frequency, rate or extent of ERBB3 signaling pathway.


sour taste receptor activity

description: Combining with soluble sour compounds to initiate a change in cell activity. These receptors are responsible for the sense of sour taste.


name: negative regulation of antigen receptor-mediated signaling pathway

description: Any process that stops, prevents, or reduces the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B- or T cell.


description: The chemical reactions and pathways resulting in the formation of a UDP-4-deoxy-4-formamido-beta-L-arabinopyranose.


name: effector-mediated modulation of host defenses by symbiont

description: A process mediated by a molecule secreted by a symbiont that results in the modulation (either activation or suppression) of a defense response. The host is defined as the larger of the organisms involved in a symbiotic interaction.


name: negative regulation of hypoxia-inducible factor-1alpha signaling pathway

description: Any process that stops, prevents or reduces the frequency, rate or extent of hypoxia-inducible factor-1alpha signaling pathway.


L-dopa biosynthetic process

description: The chemical reactions and pathways resulting in the formation of L-dopa.


serine phosphorylation of STAT protein

description: The process of introducing a phosphate group to a serine residue of a STAT (Signal Transducer and Activator of Transcription) protein.


response to interferon-alpha

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-alpha stimulus. Interferon-alpha is a type I interferon.


viral budding

description: A viral process by which enveloped viruses acquire a host-derived membrane enriched in viral proteins to form their external envelope. The process starts when nucleocapsids, assembled or in the process of being built, induce formation of a membrane curvature in the host plasma or organelle membrane and wrap up in the forming bud. The process ends when the bud is eventually pinched off by membrane scission to release the enveloped particle into the lumenal or extracellular space.


cellular respiration

description: The enzymatic release of energy from inorganic and organic compounds (especially carbohydrates and fats) which either requires oxygen (aerobic respiration) or does not (anaerobic respiration).


mandelate metabolic process

description: The chemical reactions and pathways involving mandelate, the anion of mandelic acid. Mandelic acid (alpha-hydroxybenzeneacetic acid) is an 8-carbon alpha-hydroxy acid (AHA) that is used in organic chemistry and as a urinary antiseptic.


name: positive regulation of carbohydrate metabolic process

description: Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving carbohydrate.


name: cis-14-hydroxy-10,13-dioxo-7-heptadecenoic acid peptidyl-aspartate ester biosynthetic process from peptidyl-aspartic acid

description: The modification of peptidyl-aspartic acid to form peptidyl-cis-14-hydroxy-10,13-dioxo-7-heptadecenoic acid aspartate ester, typical of the barley lipid transfer protein 1.


protein cis-autophosphorylation

description: The phosphorylation by a protein of one or more of its own amino acid residues.


name: rRNA (uridine) methyltransferase activity

description: Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing methyluridine.


name: modulation by symbiont of host erythrocyte aggregation

description: Any process in which a symbiont organism modulates the frequency, rate or extent of erythrocyte aggregation in its host organism, e.g. the binding of parasite-infected erythrocytes to uninfected erythrocytes.


hexose biosynthetic process

description: The chemical reactions and pathways resulting in the formation of hexose, any monosaccharide with a chain of six carbon atoms in the molecule.


name: citrate secondary active transmembrane transporter activity

description: Enables the transfer of citrate from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters.


trichloroethylene catabolic process

description: The chemical reactions and pathways resulting in the breakdown of trichloroethylene, a toxic, colorless, photoreactive, chlorinated hydrocarbon liquid, commonly used as a metal degreaser and solvent.


proacrosomal vesicle fusion

description: Fusion of the membrane of proacrosomal vesicle with the membrane of another proacrosomal vesicle to form the acrosome.


name: G protein-coupled serotonin receptor activity

description: Combining with the biogenic amine serotonin and transmitting the signal across the membrane by activating an associated G-protein. Serotonin (5-hydroxytryptamine) is a neurotransmitter and hormone found in vertebrates and invertebrates.


name: W-molybdopterin cofactor metabolic process

description: The chemical reactions and pathways involving the W-molybdopterin cofactor, essential for the catalytic activity of some enzymes. The cofactor consists of a mononuclear tungsten ion (W) coordinated by one or two molybdopterin ligands.


name: envenomation resulting in positive regulation of mast cell degranulation in another organism

description: A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant positive regulation of blood mast cell degranulation in the bitten organism.


name: rolling circle double-stranded viral DNA replication

description: A rolling circle viral DNA replication that begins with a double-stranded viral DNA genome.


uracil DNA N-glycosylase activity

description: Catalysis of the cleavage of the N-C1' glycosidic bond between the damaged DNA base and the deoxyribose sugar, releasing a free base and leaving an apyrimidinic (AP) site. Enzymes with this activity recognize and remove uracil bases in DNA that result from the deamination of cytosine or the misincorporation of dUTP opposite an adenine.


Rab protein signal transduction

description: An intracellular signaling cassette in which a small monomeric GTPase of the Rab subfamily relays a signal.


peptidyl-lysine succinylation

description: The modification of a peptidyl-lysine residue by the addition of a succinyl group (CO-CH2-CH2-CO) to form N6-succinyl-L-lysine.


MHC class II receptor activity

description: Combining with an MHC class II protein complex and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


name: regulation of mitochondrial DNA metabolic process

description: Any process that modulates the frequency, rate or extent of mitochondrial DNA metabolic process.


myeloid leukocyte cytokine production

description: Any process that contributes to cytokine production by a myeloid cell.


name: peptidyl-S-farnesyl-L-cysteine biosynthetic process from peptidyl-cysteine

description: The modification of peptidyl-cysteine to form peptidyl-S-farnesyl-L-cysteine; formation of S-farnesycysteine may be coupled with subsequent cleavage of a carboxy-terminal tripeptide for the CXXX motif and methyl esterification of the farnesylated cysteine; the residue may be found at the first position in the sequence motif C-X-X-(SAQCMT)* where the second and third positions are usually aliphatic.


name: ABC-type capsular-polysaccharide transporter activity

description: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + capsular polysaccharide(in) = ADP + phosphate + capsular polysaccharide(out).


name: G protein-coupled neurotransmitter receptor activity involved in regulation of presynaptic membrane potential

description: G protein-coupled neurotransmitter receptor activity, occurring in the presynaptic membrane, involved in regulation of presynaptic membrane potential.


name: negative regulation of adaptive immune memory response

description: Any process that stops, prevents or reduces the frequency, rate or extent of adaptive immune memory response.


homocysteine catabolic process

description: The chemical reactions and pathways resulting in the breakdown of homocysteine, the amino acid alpha-amino-gamma-mercaptobutanoic acid.


name: ligand-gated monoatomic cation channel activity

description: Enables the transmembrane transfer of an inorganic cation by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts.


name: negative regulation of cytokinesis, site selection

description: Any process that stops, prevents, or reduces the frequency, rate or extent of site selection that occurs as part of cytokinesis.


name: positive regulation of cardiac muscle fiber development

description: Any process that activates, maintains or increases the frequency, rate or extent of cardiac muscle fiber development.


mitochondrial depolarization

description: The process in which the potential difference across the mitochondrial membrane is reduced from its steady state level.


acyl glucuronidation

description: The modification of an substrate by the conjugation of glucuronic acid to form an acyl-glucuronide (also called an acyl-glucuronoside).


6-sulfoquinovose(1-) catabolic process

description: The chemical reactions and pathways resulting in the breakdown of 6-sulfoquinovose(1-).


name: positive regulation of toll-like receptor 11 signaling pathway

description: Any process that activates or increases the frequency, rate, or extent of toll-like receptor 11 signaling pathway.


name: 11-beta-hydroxysteroid dehydrogenase [NAD(P)+] activity

description: Catalysis of the reaction: an 11-beta-hydroxysteroid + NAD(P)+ = an 11-oxosteroid + NAD(P)H + H+.


protein activation cascade

description: A sequential series of modifications to a set of proteins where the product of one reaction catalyzes the following reaction, ultimately leading to the generation of a mature protein. Modifications typically include proteolysis or covalent modification, and may also include binding events.


urea metabolic process

description: The chemical reactions and pathways involving urea, the water soluble compound O=C-(NH2)2.


futile creatine cycle

description: The phosphorylation and dephosphorylation of creatine in a futile cycle, which dissipates the high energy charge of phosphocreatine as heat without performing any mechanical or chemical work. The futile creatine cycle takes place in thermogenic fat cells and is part of adaptive thermogenesis.


name: positive regulation of neutrophil mediated killing of symbiont cell

description: Any process that increases the frequency, rate or extent of the directed killing of a symbiont target cell by a neutrophil.


sulfonylurea receptor activity

description: Combining with sulfonylurea, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


name: hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds

description: Catalysis of the hydrolysis of any carbon-nitrogen bond, C-N, with the exception of peptide bonds.


name: negative regulation of nervous system development

description: Any process that stops, prevents, or reduces the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue.


phytol metabolic process

description: The chemical reactions and pathways involving phytol, (2E,7R,11R)-3,7,11,15-tetramethylhexadec-2-en-1-ol.


name: positive regulation of stress-activated protein kinase signaling cascade

description: Any process that activates or increases the frequency, rate or extent of signaling via the stress-activated protein kinase signaling cascade.


name: protein localization to basal ectoplasmic specialization

description: A process in which a protein is transported to, or maintained in, a location within a basal ectoplasmic specialization.


name: fibroblast growth factor receptor apoptotic signaling pathway

description: An apoptotic signaling pathway that starts with a ligand binding to, or being withdrawn from, a fibroblast growth factor receptor (FGFR).


name: regulation of primitive erythrocyte differentiation

description: Any process that modulates the rate, frequency, or extent of primitive erythrocyte differentiation. Primitive erythrocyte differentiation occurs as part of the process of primitive hemopoiesis.


sesquiterpenoid catabolic process

description: The chemical reactions and pathways resulting in the breakdown of sesquiterpenoid compounds, terpenoids with three isoprene units.


name: tRNA aminoacylation for mitochondrial protein translation

description: The synthesis of aminoacyl tRNA by the formation of an ester bond between the 3'-hydroxyl group of the most 3' adenosine of the tRNA, to be used in ribosome-mediated polypeptide synthesis in a mitochondrion.


name: regulation of peptidoglycan recognition protein signaling pathway

description: Any process that modulates the rate, frequency, or extent of the peptidoglycan recognition protein signaling pathway.


name: all-trans-nonaprenyl-diphosphate synthase (geranylgeranyl-diphosphate specific) activity

description: Catalysis of the reaction: geranylgeranyl diphosphate + 5 isopentenyl diphosphate = 5 diphosphate + all-trans-nonaprenyl diphosphate.


name: intrinsic apoptotic signaling pathway in response to oxidative stress

description: The series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced in response to oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, and ends when the execution phase of apoptosis is triggered.


glucosyltransferase activity

description: Catalysis of the transfer of a glucosyl group to an acceptor molecule, typically another carbohydrate or a lipid.


name: positive regulation of mitotic centrosome separation

description: Any process that activates or increases the frequency, rate or extent of centrosome separation.


name: protein localization involved in acrosome reaction

description: The actin-based process in which a protein is transported to, or maintained in, a specific location in the sperm as part of the acrosome reaction.


name: protein localization to chloroplast starch grain

description: A process in which a protein is transported to, or maintained in, a location within a chloroplast starch grain.


box C/D sno(s)RNA processing

description: Any process involved in the conversion of a primary box C/D type small RNA transcript into a mature box C/D RNA.


name: envenomation resulting in negative regulation of blood pressure in another organism

description: A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant decrease of the force with which blood travels through the circulatory system of the bitten/stung organism.


cellular response to bacteriocin

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bacteriocin stimulus. A bacteriocin is a protein substance released by certain bacteria that kills but does not lyse closely related strains of bacteria. Specific bacteriocins attach to specific receptors on cell walls and induce specific metabolic block, e.g. cessation of nucleic acid or protein synthesis of oxidative phosphorylation.


epinephrine catabolic process

description: The chemical reactions and pathways resulting in the breakdown of epinephrine, a hormone produced by the medulla of the adrenal glands that increases heart activity, improves the power and prolongs the action of muscles, and increases the rate and depth of breathing. It is synthesized by the methylation of norepinephrine.


name: Mo-molybdopterin cofactor biosynthetic process

description: The chemical reactions and pathways resulting in the formation of the Mo-molybdopterin cofactor, essential for the catalytic activity of some enzymes. The cofactor consists of a mononuclear molybdenum (Mo) ion coordinated by one or two molybdopterin ligands.


kinetochore organization

description: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the kinetochore, a multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules.


name: positive regulation of type I interferon-mediated signaling pathway

description: Any process that increases the rate, frequency or extent of a type I interferon-mediated signaling pathway.


UDP-D-galactose metabolic process

description: The chemical reactions and pathways involving UDP-D-galactose, a substance composed of D-galactose in glycosidic linkage with guanosine diphosphate.


guanosine metabolic process

description: The chemical reactions and pathways involving guanine, guanine riboside, a nucleoside with a wide species distribution.


name: protein N-linked N-acetylglucosaminylation via asparagine

description: A process of protein N-linked glycosylation via asparagine in which N-acetylglucosamine is added to the N4 of asparagine, forming an (S)-2-amino-4-(2-acetamido-2-deoxy-beta-D-glucopyranosyl)amino-4-oxobutanoic acid residue.


name: regulation of type III site-specific deoxyribonuclease activity

description: Any process that modulates the frequency, rate or extent of a type III restriction endodeoxyribonuclease activity.


averantin metabolic process

description: The chemical reactions and pathways involving averantin.


regulation of wound healing

description: Any process that modulates the rate, frequency, or extent of the series of events that restore integrity to a damaged tissue, following an injury.


glyoxal catabolic process

description: The chemical reactions and pathways resulting in the breakdown of glyoxal.


name: establishment of mitochondrion localization by microtubule attachment

description: The directed movement of a mitochondrion by attachment to a microtubule, followed by elongation of the microtubule by tubulin polymerization.


sucrose synthase activity

description: Catalysis of the reaction: UDP-glucose + D-fructose = UDP + sucrose.


glutamate receptor signaling pathway

description: The series of molecular signals initiated by the binding of glutamate to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.


name: plant-type cell wall cellulose catabolic process

description: The chemical reactions and pathways resulting in the breakdown of cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation, which forms part of the cell wall.


name: pregnan-21-ol dehydrogenase (NAD+) activity

description: Catalysis of the reaction: NAD+ + pregnan-21-ol = H+ + NADH + pregnan-21-al.


hypoxanthine catabolic process

description: The chemical reactions and pathways resulting in the breakdown of hypoxanthine, 6-hydroxy purine, an intermediate in the degradation of adenylate. Its ribonucleoside is known as inosine and its ribonucleotide as inosinate.


insulin metabolic process

description: The chemical reactions and pathways involving insulin.


name: semaphorin-plexin signaling pathway involved in outflow tract morphogenesis

description: The series of molecular signals generated as a consequence of a semaphorin receptor (composed of a plexin and a neurophilin) binding to a semaphorin ligand that contributes to outflow tract morphogenesis.


arginine catabolic process to glutamate

description: The chemical reactions and pathways resulting in the breakdown of arginine into other compounds, including glutamate.


cysteinyl leukotriene receptor activity

description: Combining with a cysteinyl leukotriene to initiate a change in cell activity. Cysteinyl leukotrienes are leukotrienes that contain a peptide group based on cysteine.


name: negative regulation of voltage-gated sodium channel activity in another organism

description: Any process in which an organism stops, prevents or reduces the frequency, rate or extent of the activity of a voltage-gated sodium channel in another organism.


name: regulation of tetrapyrrole biosynthetic process

description: Any process that modulates the frequency, rate or extent of tetrapyrrole biosynthetic process.


protein flavinylation

description: The addition of a flavin group to a protein amino acid.


name: symbiont-mediated suppression of host PKR/eIFalpha signaling

description: A process in which a symbiont inhibits or disrupts host PKR (Protein Kinase regulated by RNA) signaling. PKR phosphorylates host targets such as the translation initiation factor eIF2alpha that inhibits protein synthesis as an antimicrobial response. Inhibition of host PKR signaling maintains the host ability to translate mRNA. The host is defined as the larger of the organisms involved in a symbiotic interaction.


name: dermatan sulfate proteoglycan biosynthetic process

description: The chemical reactions and pathways resulting in the formation of dermatan sulfate proteoglycan, any glycoprotein whose glycosaminoglycan units are dermatan sulfate (chondroitin sulfate B). Dermatan sulfate is a glycosaminoglycan with repeats consisting of beta-(1,4)-linked L-iduronyl-beta-(1,3)-N-acetyl-D-galactosamine 4-sulfate units.


emericellamide biosynthetic process

description: The chemical reactions and pathways resulting in the formation of emericellamide.


description: The chemical reactions and pathways involving phosphatidyl-N-monomethylethanolamine (PMME), a derivative of phosphatidylethanolamine with a methylated amine group. Present in trace levels in plants and slightly higher in bacteria.


name: inositol diphosphate tetrakisphosphate diphosphatase activity

description: Catalysis of the reaction: diphospho-1D-myo-inositol tetrakisphosphate + H2O = 1D-myo-inositol pentakisphosphate + phosphate.


proteasome storage granule assembly

description: The aggregation, arrangement and bonding together of a set of components to form a proteasome storage granule.


molecular transducer activity

description: A compound molecular function in which an effector function is controlled by one or more regulatory components.


name: symbiont-mediated suppression of host tumor necrosis factor-mediated signaling pathway

description: A process in which a virus interferes with, inhibits or disrupts a tumor necrosis factor-mediated signal transduction in its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.


name: cellular response to methyl methanesulfonate

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methyl methanesulfonate (MMS) stimulus.


TMP biosynthetic process

description: The chemical reactions and pathways resulting in the formation of TMP, ribosylthymine monophosphate.


late viral transcription

description: The transcription of the final group of viral genes of the viral life cycle, following middle transcription, or where middle transcription doesn't occur, following early transcription. Involves the transcription of genes encoding structural proteins.


anaerobic lactate catabolic process

description: The chemical reactions and pathways resulting in the breakdown of lactate (2-hydroxypropanoic acid) in the absence of oxygen.


name: voltage-gated sodium channel activity involved in bundle of His cell action potential

description: Enables the transmembrane transfer of a sodium ion by a voltage-gated channel through the plasma membrane of a bundle of His cardiac muscle cell contributing to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.


name: monounsaturated fatty acid metabolic process

description: The chemical reactions and pathways involving monounsaturated fatty acid.


gramicidin S biosynthetic process

description: The chemical reactions and pathways resulting in the formation of gramicidin S.


name: G protein-coupled serotonin receptor signaling pathway

description: The series of molecular signals generated as a consequence of a G protein-coupled serotonin receptor binding to one of its physiological ligands.


name: pyrimidine deoxyribonucleoside metabolic process

description: The chemical reactions and pathways involving any one of a family of organic molecules consisting of a pyrimidine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside).


name: positive regulation of TRAIL-activated apoptotic signaling pathway

description: Any process that activates or increases the frequency, rate or extent of TRAIL-activated apoptotic signaling pathway.


name: extracellular matrix organization involved in endocardium development

description: A process which results in the assembly, arrangement of constituent parts, or disassembly of an extracellular matrix of the endocardium. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers.


nitrogenous compound fermentation

description: The anaerobic chemical reactions and pathways resulting in the breakdown of a nitrogen-containing compound, yielding energy in the form of ATP.


name: protein localization to microvillus membrane

description: A process in which a protein is transported to, or maintained in, a location within a microvillus membrane.


acetylglucosaminyltransferase activity

description: Catalysis of the transfer of an N-acetylglucosaminyl residue from UDP-N-acetyl-glucosamine to a sugar.


macromolecule deacylation

description: The removal of an acyl group, any group or radical of the form RCO- where R is an organic group, from a macromolecule.


glycoside biosynthetic process

description: The chemical reactions and pathways resulting in the formation of glycosides, compounds in which a glycosyl group is substituted into a hydroxyl, thiol or selenol group in another compound.


oxysterol receptor signaling pathway

description: A nuclear receptor-mediated signaling pathway initiated by an oxysterol binding to an intracellular receptor of the nuclear receptor protein family, and ending with regulation of a downstream cellular process, e.g. transcription.


bicyclogermacrene metabolic process

description: The chemical reactions and pathways involving bicyclogermacrene.


name: symbiont-mediated perturbation of host cell-cell junction

description: The process in which an organism effects a change that impairs the structure or temporarily subverts the host intercellular junction. Intercellular junction include tight junctions and adherens junctions.


name: positive regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis

description: Any process that activates or increases the frequency, rate or extent of cardiac neural crest cell migration involved in outflow tract morphogenesis.


21U-RNA metabolic process

description: The chemical reactions and pathways involving 21U-RNAs, a class of single-stranded RNA molecules of about 21 nucleotides in length characterized by a uridine 5'-monophosphate and a modified 3' end resistant to periodate degradation. 21U-RNAs are derived from distinct, autonomously expressed loci within the genome.


name: folic acid-containing compound catabolic process

description: The chemical reactions and pathways resulting in the breakdown of folic acid and its derivatives.


queuosine biosynthetic process

description: The chemical reactions and pathways resulting in the formation of queuosines, a series of nucleosides found in tRNA and having an additional pentenyl ring added via an NH group to the methyl group of 7-methylguanosine. The pentenyl ring may carry other substituents.


description: Catalysis of the reaction: UDP-N-acetyl-D-galactosamine + glycoprotein-alpha-L-fucosyl-(1,2)-D-galactose = UDP + glycoprotein-N-acetyl-alpha-D-galactosaminyl-(1,3)-(alpha-L-fucosyl-(1,2))-D-galactose.


response to host

description: Any process that results in a change in state or activity of the symbiont or its cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.


leucoplast organization

description: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a leucoplast. A leucoplast is a colorless plastid involved in the synthesis of monoterpenes.


name: positive regulation of myotube differentiation

description: Any process that activates, maintains or increases the frequency, rate or extent of myotube differentiation. Myotube differentiation is the process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse.


name: bundle of His cell to Purkinje myocyte signaling

description: Any process that mediates the transfer of information from a bundle of His cardiomyocyte to a Purkinje myocyte.


name: peptidyl-L-glutamyl 5-glycerylphosphorylethanolamine biosynthetic process from peptidyl-glutamic acid

description: The modification of peptidyl-glutamic acid residues by the covalent attachment of ethanolamine, itself further modified by the addition of a phosphoglycerol unit.


snRNA methyltransferase activity

description: Catalysis of the transfer of a methyl group from a donor to a nucleoside residue in an snRNA molecule.


telomere maintenance via recombination

description: Any recombinational process that contributes to the maintenance of proper telomeric length.


cilium movement

description: The directed, self-propelled movement of a cilium.


name: negative regulation of neuron apoptotic process

description: Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process in neurons.


norepinephrine biosynthetic process

description: The chemical reactions and pathways resulting in the formation of norepinephrine, a hormone secreted by the adrenal medulla, and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts in the central nervous system. It is also the demethylated biosynthetic precursor of epinephrine.


name: negative regulation of Wnt signaling pathway

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the Wnt signaling pathway.


ribosome assembly

description: The aggregation, arrangement and bonding together of the mature ribosome and of its subunits.


name: positive regulation of macromolecule metabolic process

description: Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.


name: protein localization to endoplasmic reticulum exit site

description: A process in which a protein is transported to, or maintained in, a location at an endoplasmic reticulum exit site.


orlandin metabolic process

description: The chemical reactions and pathways involving orlandin.


aerobic benzoate metabolic process

description: The chemical reactions and pathways involving benzoate, the anion of benzoic acid (benzenecarboxylic acid) that occur in the presence of oxygen.


response to insect

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from an insect.


xylene metabolic process

description: The chemical reactions and pathways involving xylene, a mixture of three colorless, aromatic hydrocarbon liquids, ortho-, meta- and para-xylene.


name: inositol 1,4,5-trisphosphate-gated calcium channel activity

description: Enables the transmembrane transfer of a calcium ion by a channel that opens when inositol 1,4,5-trisphosphate (IP3) has been bound by the channel complex or one of its constituent parts.


2,4,6-trinitrotoluene metabolic process

description: The chemical reactions and pathways involving 2,4,6-trinitrotoluene, 1-methyl-2,4,6-trinitrobenzene, a highly explosive pale yellow crystalline solid. It is prepared from toluene treated with concentrated sulfuric and nitric acids and is used in shells, bombs, and blasting explosives.


name: phosphatidylcholine biosynthesis from phosphoryl-ethanolamine via CDP-N-methylethanolamine

description: The phosphatidylcholine biosynthetic process that begins with an initial N-methylation with phospho-base phosphoethanolamine, followed by two downstream N-methylations on phosphatidyl-bases, phosphatidyl-N-methylethanolamine and phosphatidyl-N-dimethylethanolamine. The process ends with the conversion of a phosphatidyl-N-dimethylethanolamine to a phosphatidylcholine.


name: light-dependent bacteriochlorophyll biosynthetic process

description: The chemical reactions and pathways resulting in the formation of a bacteriochlorophyll, which occur in the presence of light. Bacteriochlorophylls are any of the chlorophylls of photosynthetic bacteria; they differ structurally from the chlorophylls of higher plants.


name: U2 snRNA 2'-O-methyladenosine m6 methyltransferase activity

description: Catalysis of the reaction: a 2'-O-methyladenosine in U2 snRNA + S-adenosyl-L-methionine = an N6-methyl-2'-O-methyladenosine in U2 snRNA + S-adenosyl-L-homocysteine + H+.


dUDP biosynthetic process

description: The chemical reactions and pathways resulting in the formation of dUDP, deoxyuridine diphosphate (2'-deoxy-5'-uridylyl phosphate).


name: apoptotic process involved in tube lumen cavitation

description: Any apoptotic process that contributes to the hollowing out of an epithelial rod or cord to form the central hole in a tube.


phosphatidylserine metabolic process

description: The chemical reactions and pathways involving phosphatidylserines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of L-serine. They are important constituents of cell membranes.


name: regulation of (Z)-nonadeca-1,14-diene biosynthetic process

description: Any process that modulates the frequency, rate or extent of (Z)-nonadeca-1,14-diene biosynthetic process.


name: positive regulation of peroxisome proliferator activated receptor signaling pathway

description: Any process that activates or increases the frequency, rate or extent of the peroxisome proliferator activated receptor signaling pathway.


phosphatidic acid metabolic process

description: The chemical reactions and pathways involving phosphatidic acid, any derivative of glycerol phosphate in which both the remaining hydroxyl groups of the glycerol moiety are esterified with fatty acids.


name: cellular response to mechanical stimulus

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mechanical stimulus.


name: vesicle fusion with Golgi cis cisterna membrane

description: The joining of the lipid bilayer membrane around a vesicle to the lipid bilayer membrane around the Golgi cis cisterna. This can involve anterograde or retrograde transport vesicles.


B cell mediated immunity

description: Any process involved with the carrying out of an immune response by a B cell, through, for instance, the production of antibodies or cytokines, or antigen presentation to T cells.


neuromuscular synaptic transmission

description: The process of synaptic transmission from a neuron to a muscle, across a synapse.


name: pyrroloquinoline quinone biosynthetic process

description: The chemical reactions and pathways resulting in the formation of the cofactor pyrroloquinoline quinone (PQQ); it is synthesized from a small peptide containing tyrosine and glutamic acid; these amino acids in the peptide are multiply cross-linked and the rest of the peptide is removed.


G protein-coupled receptor activity

description: Combining with an extracellular signal and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.


protein palmitoylation

description: The covalent attachment of a palmitoyl group to a protein.