name: YJ151_YEAST Uncharacterized protein YJR151W-A (sprot)

description: A protein that is a translation product of the YJR151W-A gene in yeast.


CAAX prenyl protease 2

A protein that is a translation product of the human RCE1 gene or a 1:1 ortholog thereof.


name: CAAX prenyl protease 2 isoform 1 (mouse)

description: A CAAX prenyl protease 2 isoform 1 that is encoded in the genome of mouse.


name: CAAX prenyl protease 2, initiator methionine removed form (human)

description: A CAAX prenyl protease 2 (human) that has had the initiator methionine removed. UniProtKB:Q9Y256, 2-329.


CAAX prenyl protease 2 isoform 1

A CAAX prenyl protease 2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9Y256-1 or a 1:1 ortholog thereof.


name: CAAX prenyl protease 2, initiator methionine removed ubiquitinated form (human)

description: A CAAX prenyl protease 2 (human) that has had the initiator methionine removed and that includes at least one ubiquitinated lysine. UniProtKB:Q9Y256, 2-329, MOD:01148.


name: Q54D25_DICDI Uncharacterized protein (trembl)

description: A CAAX prenyl protease 2 that is encoded in the genome of Dictyostelium discoideum.


name: CAAX prenyl protease 2 isoform 1 (human)

description: A CAAX prenyl protease 2 isoform 1 that is encoded in the genome of human.


name: FACE2_ARATH CAAX prenyl protease 2 (sprot)

description: A CAAX prenyl protease 2 that is encoded in the genome of Arabidopsis thaliana.


flagellar P-ring protein

A protein that is a translation product of the Escherichia coli K-12 flgI gene or a 1:1 ortholog thereof.


name: FLGI_ECOLI Flagellar P-ring protein (sprot)

description: A flagellar P-ring protein that is encoded in the genome of Escherichia coli K-12.


MLF3_YEAST Protein MLF3 (sprot)

A protein that is a translation product of the MLF3 gene in yeast.


name: ragulator complex protein LAMTOR3 isoform 1 (mouse)

description: A mitogen-activated protein kinase scaffold protein 1 isoform 1 that is encoded in the genome of mouse.


funisitis

category: biolink:Disease biolink:DiseaseOrPhenotypicFeature biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing

description: An acute inflammation of the umbilical cord. It is characterized by the presence of polymorphonuclear cells migrating from the fetal umbilical cord vessels through the umbilical cord towards the bacteria containing amniotic fluid.


Necrotizing Funisitis

description: A ring of karyorrhectic debris that may exhibit dystrophic mineralization and/or identifiable fetal neutrophil infiltrate in Wharton's jelly that is oriented towards the amniotic surface. The cord has a denser ring externally and a fainter ring centrally.


name: macrophage migration inhibitory factor isoform 1 (chicken)

description: A macrophage migration inhibitory factor isoform 1 that is encoded in the genome of chicken.


name: E3 ubiquitin-protein ligase Hakai isoform 1

description: An E3 ubiquitin-protein ligase Hakai that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q75N03-1 or a 1:1 ortholog thereof.


name: E3 ubiquitin-protein ligase Hakai isoform 1 (mouse)

description: An E3 ubiquitin-protein ligase Hakai isoform 1 that is encoded in the genome of mouse.


name: E3 ubiquitin-protein ligase Hakai isoform 1 (human)

description: An E3 ubiquitin-protein ligase Hakai isoform 1 that is encoded in the genome of human.


name: NOTC1_DANRE Neurogenic locus notch homolog protein 1 (sprot)

description: A protein that is a translation product of the notch1a gene in zebrafish.


name: CINV2_ARATH Alkaline/neutral invertase CINV2 (sprot)

description: A protein that is a translation product of the CINV2 gene in Arabidopsis thaliana.


name: alkaline/neutral invertase CINV2 isoform 1 (Arabidopsis thaliana)

description: An alkaline/neutral invertase CINV2 (Arabidopsis thaliana) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q67XD9-1.


name: alkaline/neutral invertase CINV2 isoform 2 (Arabidopsis thaliana)

description: An alkaline/neutral invertase CINV2 (Arabidopsis thaliana) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q67XD9-2.


name: serine/arginine-rich splicing factor RS2Z33 isoform 2 (Arabidopsis thaliana)

description: A serine/arginine-rich splicing factor RS2Z33 (Arabidopsis thaliana) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8VYA5-2.


name: RSZ33_ARATH Serine/arginine-rich splicing factor RS2Z33 (sprot)

description: A protein that is a translation product of the RS2Z33 gene in Arabidopsis thaliana.


name: serine/arginine-rich splicing factor RS2Z33 isoform 1 (Arabidopsis thaliana)

description: A serine/arginine-rich splicing factor RS2Z33 (Arabidopsis thaliana) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8VYA5-1.


name: serine/arginine-rich splicing factor RS2Z33 isoform 3 (Arabidopsis thaliana)

description: A serine/arginine-rich splicing factor RS2Z33 (Arabidopsis thaliana) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8VYA5-3.


name: integrin beta-2-like protein isoform m1 (mouse)

description: An integrin beta-2-like protein (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q3UV74-1.


integrin beta-2-like protein

An integrin beta that is a translation product of the mouse Itgb2l gene or a 1:1 ortholog thereof.


name: integrin beta-2-like protein isoform m2 (mouse)

description: An integrin beta-2-like protein (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q3UV74-2.


name: ITB2L_MOUSE Integrin beta-2-like protein (sprot)

description: An integrin beta-2-like protein that is encoded in the genome of mouse.


name: integrin beta-2-like protein isoform m3 (mouse)

description: An integrin beta-2-like protein (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q3UV74-3.


PHL21_ARATH Phytolongin Phyl2.1 (sprot)

A protein that is a translation product of the PHYL2.1 gene in Arabidopsis thaliana.


name: blood group Rh(D) polypeptide isoform h6 (human)

description: A blood group Rh(D) polypeptide (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q02161-6.


name: spectrin beta chain, non-erythrocytic 2 isoform h1 (human)

description: A spectrin beta chain, non-erythrocytic 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O15020-1.


pilocarpine

The (+)-enantiomer of pilocarpine.


name: NDPA_ECOLI Nucleoid-associated protein YejK (sprot)

description: A nucleoid-associated protein ndpA that is encoded in the genome of Escherichia coli K-12.


RNU2_USTSP Ribonuclease U2 (sprot)

A ribonuclease U2 that is encoded in the genome of Ustilago sphaerogena.


Ustilago sphaerogena protein

A protein that is encoded in the genome of Ustilago sphaerogena.


name: collagen alpha-1(XV) chain, signal peptide removed galactosylhydroxylysine form (human)

description: A collagen alpha-1(XV) chain (human) that has had the signal peptide removed and that includes at least 1 galactosylhydroxylated lysine. UniProtKB:P39059, 28-1388, MOD:01914.


name: Non-Functioning Pancreatic Neuroendocrine Tumor G2

description: An intermediate grade well differentiated neoplasm with neuroendocrine differentiation that arises from the pancreas. It is characterized by the absence of a hormone-related clinical syndrome.


Pancreatic Neuroendocrine Tumor G2

description: A well differentiated, intermediate grade neoplasm with neuroendocrine differentiation that arises from the pancreas. The mitotic count is 2-20 per 10 HPF and/or the Ki67 index is 3-20%.


name: Advanced Pancreatic Neuroendocrine Tumor G2

description: Pancreatic neuroendocrine tumor G2 that has spread extensively to other anatomic sites or is no longer responding to treatment.


name: Functioning Pancreatic Neuroendocrine Tumor G2

description: A well differentiated, intermediate grade neoplasm with neuroendocrine differentiation that arises from the pancreas. It is characterized by the presence of a clinical syndrome that results from hormone hypersecretion.


name: Metastatic Pancreatic Neuroendocrine Tumor G2

description: Pancreatic neuroendocrine tumor G2 that has spread from its original site of growth to another anatomic site.


name: RL34_BORPE Large ribosomal subunit protein bL34 (sprot)

description: A protein that is a translation product of the rpmH gene in Bordetella pertussis Tohama I.


name: PIGM_DANRE GPI mannosyltransferase 1 (sprot)

description: A GPI mannosyltransferase 1 that is encoded in the genome of zebrafish.


name: PME36_ARATH Probable pectinesterase/pectinesterase inhibitor 36 (sprot)

description: A protein that is a translation product of the PME36 gene in Arabidopsis thaliana.


name: GILT-like protein C02D5.2 isoform b (worm)

description: A GILT-like protein C02D5.2 (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P34276-2.


name: pre T-cell antigen receptor alpha, signal peptide removed form (human)

description: A pre T-cell antigen receptor alpha (human) that has had the signal peptide removed. Example: UniProtKB:Q6ISU1-1, 24-281.


name: OLIG3_MOUSE Oligodendrocyte transcription factor 3 (sprot)

description: An oligodendrocyte transcription factor 3 that is encoded in the genome of mouse.


name: SNAPN_MOUSE SNARE-associated protein Snapin (sprot)

description: A SNARE-associated protein Snapin that is encoded in the genome of mouse.


name: SNARE-associated protein Snapin isoform m2 (mouse)

description: A SNARE-associated protein Snapin (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9Z266-2.


name: SNARE-associated protein Snapin isoform 1 (mouse)

description: A SNARE-associated protein Snapin isoform 1 that is encoded in the genome of mouse.


name: 2-quinolinecarboxylic acid (2-oxo-3-oxolanyl) ester


name: interleukin-23 subunit alpha isoform 1 (rat)

description: An interleukin-23 subunit alpha isoform 1 that is encoded in the genome of rat.


name: PSB2_CAEEL Proteasome subunit beta type-2 (sprot)

description: A proteasome subunit beta type-2 that is encoded in the genome of worm.


name: glutamate-gated chloride channel isoform D (fruit fly)

description: A glutamate-gated chloride channel (fruit fly) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q94900-5.


beta-D-glucosylsphingosine

D-Glucosylsphingosine in which the anomeric configuration of the glucosyl moiety is beta.


Cyflometofen

A nitrile that is acetonitrile in which the methyl hydrogens have been replaced by o-trifluoromethylbenzoyl, p-tert-butylphenyl, and (2-methoxyethoxy)carbonyl groups.


(S)-cyflumetofen

A 2-methoxyethyl 2-(4-tert-butylphenyl)-2-cyano-3-oxo-3-[2-(trifluoromethyl)phenyl]propanoate that has S configuration.


(R)-cyflumetofen

A 2-methoxyethyl 2-(4-tert-butylphenyl)-2-cyano-3-oxo-3-[2-(trifluoromethyl)phenyl]propanoate that has R configuration.


name: positive regulation of aldosterone metabolic process

category: biolink:BiologicalProcess biolink:Occurrent biolink:OntologyClass biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving aldosterone.


name: positive regulation of aldosterone biosynthetic process

description: Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of aldosterone.


FZD10_MOUSE Frizzled-10 (sprot)

A frizzled-10 that is encoded in the genome of mouse.


A frizzled-like G-protein coupled receptor that is a translation product of the human FZD10 gene or a 1:1 ortholog thereof.


name: frizzled-10, signal peptide removed form (human)

description: A frizzled-10 (human) that has had the signal peptide removed. UniProtKB:Q9ULW2, 21-581.


FZD10_HUMAN Frizzled-10 (sprot)

A frizzled-10 that is encoded in the genome of human.


FZD10_CHICK Frizzled-10 (sprot)

A frizzled-10 that is encoded in the genome of chicken.


name: tubulin polymerization-promoting protein family member 3 isoform 1 (mouse)

description: A tubulin polymerization-promoting protein family member 3 isoform 1 that is encoded in the genome of mouse.


name: insulin-like growth factor 2 mRNA-binding protein 3 methylated 1 (human)

description: An insulin-like growth factor 2 mRNA-binding protein 3 (human) that has been methylated on the residue at the position equivalent to Cys-110 of the amino acid sequence represented by UniProtKB:O00425-1. Example: UniProtKB:O00425-1, Cys-110, MOD:00660.


name: CHX15_ARATH Cation/H(+) antiporter 15 (sprot)

description: A protein that is a translation product of the CHX15 gene in Arabidopsis thaliana.


name: acyl-coenzyme A thioesterase MBLAC2 isoform 1 (human)

description: An acyl-coenzyme A thioesterase MBLAC2 isoform 1 that is encoded in the genome of human.


name: inosine-5'-monophosphate dehydrogenase 2 isoform 1 (zebrafish)

description: An inosine-5'-monophosphate dehydrogenase 2 isoform 1 that is encoded in the genome of zebrafish.


name: condensin-2 complex subunit D3 methylated 4 (human)

description: A condensin-2 complex subunit D3 (human) that has been methylated on the residue at the position equivalent to Cys-471 of the amino acid sequence represented by UniProtKB:P42695. UniProtKB:P42695, Cys-471, MOD:00660.


condensin-2 complex subunit D3

A protein that is a translation product of the human NCAPD3 gene or a 1:1 ortholog thereof.


name: condensin-2 complex subunit D3 methylated 1 (human)

description: A condensin-2 complex subunit D3 (human) that has been methylated on the residue at the position equivalent to Cys-831 of the amino acid sequence represented by UniProtKB:P42695. UniProtKB:P42695, Cys-831, MOD:00660.


name: condensin-2 complex subunit D3 deaminated 2 (human)

description: A condensin-2 complex subunit D3 (human) that has been deaminated on the residue at the position equivalent to Asn-506 of the amino acid sequence represented by UniProtKB:P42695. UniProtKB:P42695, Asn-506, MOD:00684.


name: CNDD3_HUMAN Condensin-2 complex subunit D3 (sprot)

description: A condensin-2 complex subunit D3 that is encoded in the genome of human.


name: condensin-2 complex subunit D3 methylated 2 (human)

description: A condensin-2 complex subunit D3 (human) that has been methylated on the residue at the position equivalent to Cys-1059 of the amino acid sequence represented by UniProtKB:P42695. UniProtKB:P42695, Cys-1059, MOD:00660.


name: CNDD3_ARATH Condensin-2 complex subunit CAP-D3 (sprot)

description: A condensin-2 complex subunit D3 that is encoded in the genome of Arabidopsis thaliana.


name: condensin-2 complex subunit D3 methylated 3 (human)

description: A condensin-2 complex subunit D3 (human) that has been methylated on the residue at the position equivalent to Cys-387 of the amino acid sequence represented by UniProtKB:P42695. UniProtKB:P42695, Cys-387, MOD:00660.


name: condensin-2 complex subunit D3 phosphorylated 3 (human)

description: A condensin-2 complex subunit D3 (human) that has been phosphorylated on the residue at the position equivalent to Tyr-1100 of the amino acid sequence represented by UniProtKB:P42695. UniProtKB:P42695, Tyr-1100, MOD:00048.


name: condensin-2 complex subunit D3 deaminated 1 (human)

description: A condensin-2 complex subunit D3 (human) that has been deaminated on the residue at the position equivalent to Gln-1111 of the amino acid sequence represented by UniProtKB:P42695. UniProtKB:P42695, Gln-1111, MOD:00685.


name: condensin-2 complex subunit D3 phosphorylated 1 (human)

description: A condensin-2 complex subunit D3 (human) that has been phosphorylated on the residue at the position equivalent to Thr-1415 of the amino acid sequence represented by UniProtKB:P42695. UniProtKB:P42695, Thr-1415, MOD:00047.


name: condensin-2 complex subunit D3 phosphorylated 2 (human)

description: A condensin-2 complex subunit D3 (human) that has been phosphorylated on the residue at the position equivalent to Thr-1415, and phosphoserine at position 1419 of the amino acid sequence represented by UniProtKB:P42695. UniProtKB:P42695, Thr-1415, MOD:00047|Ser-1419, MOD:00046.


name: condensin-2 complex subunit D3 deaminated 3 (human)

description: A condensin-2 complex subunit D3 (human) that has been deaminated on the residue at the position equivalent to Gln-649 of the amino acid sequence represented by UniProtKB:P42695. UniProtKB:P42695, Gln-649, MOD:00685.


name: CNDD3_MOUSE Condensin-2 complex subunit D3 (sprot)

description: A condensin-2 complex subunit D3 that is encoded in the genome of mouse.


name: condensin-2 complex subunit D3 cysteinylated 1 (mouse)

description: A condensin-2 complex subunit D3 (mouse) that has been cysteinylated on the residue at the position equivalent to Cys-851 of the amino acid sequence represented by UniProtKB:Q6ZQK0. UniProtKB:Q6ZQK0, Cys-851, MOD:00765.


name: condensin-2 complex subunit D3 cysteinylated 1 (human)

description: A condensin-2 complex subunit D3 (human) that has been cysteinylated on the residue at the position equivalent to Cys-831 of the amino acid sequence represented by UniProtKB:P42695. UniProtKB:P42695, Cys-831, MOD:00765.


name: TTCA_ECOLI tRNA-cytidine(32) 2-sulfurtransferase (sprot)

description: A tRNA-cytidine(32) 2-sulfurtransferase that is encoded in the genome of Escherichia coli K-12.


tRNA-cytidine(32) 2-sulfurtransferase

A protein that is a translation product of the Escherichia coli K-12 ttcA gene or a 1:1 ortholog thereof.


name: F4I2A4_ARATH Cytoplasmic tRNA 2-thiolation protein 1 (trembl)

description: A tRNA-cytidine(32) 2-sulfurtransferase that is encoded in the genome of Arabidopsis thaliana.


alpha-enolase acetylated 1 (human)

An alpha-enolase (human) that has been acetylated on the residue at the position equivalent to Lys-5 of the amino acid sequence represented by UniProtKB:P06733-1. Example: UniProtKB:P06733-1, Lys-5, MOD:00723.


A branched amino octasaccharide consisting of a linear hexasaccharide comprising two N-acetyl-alpha-neuraminic acid residues, a beta-D-galactose residue, two L-glycero-alpha-D-manno-heptose (L-alpha-D-Hep) residues and a 3-deoxy-alpha-D-manno-oct-2-ulose (alpha-Kdo) residue linked in sequence (2->8), (2->3), (1->3),(1->3), (1->3) and (1->5), to the L-alpha-D-Hep residue proximal to the reducing end is also linked (1->4) a beta-D-glucose residue, while the alpha-Kdo residue also carries a second alpha-Kdo residue linked (2->-4). One of a number of chemoenzymatically synthesised oligosaccharides composed of the inner core oligosaccharide of Campylobacter jejuni extended by various ganglioside mimics.


autoimmune disorder of endocrine system

description: A hypersensitivity reaction type II disease that involves the endocrine system.


adenohypophysitis

description: An autoimmune disease of the pituitary gland which can present with varying degrees of pituitary hormonal impairment and/or with symptoms related to pituitary enlargement. It predominantly affects young women in pregnancy or the peripartum period.


autoimmune oophoritis

description: Autoimmune oophoritis is a rare cause of primary ovarian insufficiency (POI). It happens when the body's immune system mistakenly attacks the ovaries causing inflammation, atrophy and fibrosis. These changes stop the ovaries from working normally. The main symptoms of autoimmune oophorotis are irregular or absent menstrual period (amenorrhea) and symptoms related to ovarian cysts such as abdominal cramping, bloating, nausea and vomiting. Autoimmune oophoritis may occur as part of autoimmune polyglandular syndrome type I and type II but has also been associated with lupus, pernicious anemia, myasthenia gravis and other autoimmune conditions. The underlying cause of autoimmune oophoritis is unknown. Diagnosis involves a special blood test which looks for anti-steroid or anti-ovarian antibodies, a pelvic ultrasound to look for enlarged cystic ovaries and tests to rule out other possible causes of POI. Management of autoimmune oophoritis involves emotional support, possible estrogen replacement therapy and management of other autoimmune conditions.


thyrotoxicosis

description: A hypermetabolic syndrome caused by the elevation of thyroid hormone levels in the serum. Signs and symptoms include tachycardia, palpitations, tremor, weight loss, warm weather intolerance, and moist skin. Causes include Graves disease, toxic nodular goiter, toxic thyroid nodule, and lymphocytic thyroiditis.


atrophic thyroiditis

description: Atrophic thyroiditis is an organ-specific autoimmune disease characterized by thyroid autoantibodies, functional hypothyroidism, and absence of goiter.


primary hypophysitis

description: Immune-mediated inflammation of the pituitary gland often associated with other autoimmune diseases (e.g., hashimoto disease; graves disease; and addison disease).


autoimmune primary ovarian failure

description: An autoimmune form of primary ovarian failure.


postpartum thyroiditis

description: A transient autoimmune Inflammatory disorder of thyroid gland that occurs postpartum due to any partum problem. It is characterized by the presence of high titers of autoantibodies against thyroid peroxidase and thyroglobulin. Clinical signs include the triphasic thyroid hormone pattern: beginning with thyrotoxicosis, followed with hypothyroidism, then return to euthyroid state by 1 year postpartum


IgG4-related thyroid disease

description: Riedel thyroiditis is a fibroinflammatory disorder of the thyroid gland, occurring more frequently in females, characterized a large, hard thyroid mass, and presenting with pressure symptoms (breathing difficulB,ties and dysphagia) or voice hoarseness and aphonia (impingement of recurrent laryngeal nerve). It can often be associated with extracervical fibroinflammatory disorders such as retroperitoneal fibrosis, primary scleroisng cholangitis and autoimmune diseases such as Hashimoto struma, Addison disease, and Biermer disease.


autoimmune polyendocrinopathy

description: A group of diverse conditions that are characterized by spontaneous, multi-organ autoimmunity, which target both endocrine (adrenal, gonad, pancreatic islet cells, parathyroid, pituitary, thyroid) and non-endocrine (gastrointestinal, integumentary, lymphatic) tissues.


autoimmune thyroid disease

description: Inflammatory disease of the thyroid gland due to autoimmune responses leading to lymphocytic infiltration of the gland. It is characterized by the presence of circulating thyroid antigen-specific T-cells and thyroid autoantibodies. The clinical signs can range from hypothyroidism to thyrotoxicosis depending on the type of autoimmune thyroiditis.


neonatal thyrotoxicosis

description: A hypermetabolic syndrome characterized by tachycardia, palpitations, tremor, weight loss, and moist skin that is caused by the elevation of thyroid hormone levels in the serum of the newborn infant or thyroid-axis receptor activation, most commonly due to transplacental passage of thyroid stimulating globulins.


autoimmune polyendocrinopathy type 2

description: Autoimmune polyglandular syndrome of likely polygenic etiology characterized by the presence of primary adrenal insufficiency in association with autoimmune thyroiditis and/or type 1 diabetes mellitus; this condition is not associated with mucocutaneous candidiasis.


name: autoimmune polyendocrine syndrome type 1

description: Autoimmune polyendocrinopathy type 1, or APECED syndrome, is a genetic disease that manifests in childhood or early adolescence with a combination of chronic mucocutaneous candidiasis, hypoparathyroidism and autoimmune adrenal failure.


insulin autoimmune syndrome

description: Insulin autoimmune syndrome is a rare condition that causes low blood sugar (hypoglycemia). This occurs because the body begins to make a specific kind of protein called antibodies to attack insulin. Insulin is a naturally occurring hormone that is responsible for keeping blood sugar at a normal level. When blood sugar levels get too high, insulin helps to store the sugar for future use. People affected by insulin autoimmune syndrome have antibodies that attack insulin, causing it to work too hard and the level of blood sugar to become too low. Insulin autoimmune syndrome most often begins during adulthood.


autoimmune polyendocrinopathy type 3

description: A rare, endocrine disease characterized by autoimmune thyroid disease associated with at least one other autoimmune disease, such as type I diabetes mellitus, chronic atrophic gastritis, pernicious anemia, vitiligo, alopecia, or myasthenia gravis, but excluding Addison disease.


(E)-dehydrocyclopeptine

A geoisomer of dehydrocyclopeptine in which the C=C bond of the benzylidene substituent has E-configuration.


lactobacillic acid

An 11,12-methyleneoctadecanoic acid having (11R,12S)-configuration.


11,12-methyleneoctadecanoic acid

A C18, saturated fatty acid composed of octadecanoic acid having an 11,12-methylene substituent forming a cyclopropane.


name: ODO1_DICDI 2-oxoglutarate dehydrogenase, mitochondrial (sprot)

description: A 2-oxoglutarate dehydrogenase E1 component that is encoded in the genome of Dictyostelium discoideum.


name: putative uncharacterized protein encoded by LINC03041 isoform h2 (human)

description: A putative uncharacterized protein encoded by LINC03041 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:A6NGG3-2.


name: vesicle scission involved in endocytosis

description: The membrane scission process that is the final step in the formation of an endocytic vesicle: separation from the plasma membrane.


name: vesicle scission involved in clathrin-mediated endocytosis

description: The membrane scission process that is the final step in the formation of a clathrin-coated endocytic vesicle: separation from the plasma membrane.


name: FPGT-TNNI3K readthrough protein isoform 1 (human)

description: A chimeric protein that is a readthrough translation product of the human FPGT and TNNI3K genes that gives rise to a protein with the amino acid sequence represented by UniProtKB:Q59H18-1.


choanal atresia, ass

description: Choanal atresia that occurs in ass.


xylulose kinase isoform h2 (human)

A xylulose kinase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O75191-2.


XYLB_HUMAN Xylulose kinase (sprot)

A xylulose kinase that is encoded in the genome of human.


xylulose kinase cysteinylated 1 (human)

A xylulose kinase (human) that has been cysteinylated on the residue at the position equivalent to Cys-470 of the amino acid sequence represented by UniProtKB:O75191-1. Example: UniProtKB:O75191-1, Cys-470, MOD:00765.


xylulose kinase isoform 1 (human)

A xylulose kinase isoform 1 that is encoded in the genome of human.


scopolamine biosynthetic process

description: The chemical reactions and pathways resulting in the formation of scopolamine.


abediterol

A quinolone that is 8-hydroxyquinolin-2(1H)-one which carries a 2-{[6-(2,2-difluoro-2-phenylethoxy)hexyl]amino}-1-hydroxyethyl group at position 5. It is a long acting beta2-adrenoceptor agonist currently in development for the treatment of chronic obstructive pulmonary disease (COPD) and asthma.


name: RPB9_CAEEL DNA-directed RNA polymerase II subunit rpb-9 (sprot)

description: A DNA-directed RNA polymerase II subunit RPB9 that is encoded in the genome of worm.


name: E3 ubiquitin-protein ligase MYCBP2 methylated 1 (human)

description: An E3 ubiquitin-protein ligase MYCBP2 (human) that has been methylated on the residue at the position equivalent to Cys-2044 of the amino acid sequence represented by UniProtKB:O75592-1. Example: UniProtKB:O75592-1, Cys-2044, MOD:00660.


synapsin-2 isoform IIb (rat)

A synapsin-2 isoform 2 that is encoded in the genome of rat.


isobutrin

A member of the class of chalcones that is trans-chalcone substituted by beta-D-glucopyranosyloxy groups at positions 3 and 4' and hydroxy groups at positions 4 and 2' respectively.


name: serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform isoform 1 (human)

description: A serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform isoform 1 that is encoded in the genome of human.


name: formin-binding protein 4 deaminated 1 (human)

description: A formin-binding protein 4 (human) that has been deaminated on the residue at the position equivalent to Asn-227 of the amino acid sequence represented by UniProtKB:Q8N3X1-1. Example: UniProtKB:Q8N3X1-1, Asn-227, MOD:00684.


name: general transcription factor IIE subunit 1, initiator methionine removed form (human)

description: A general transcription factor IIE subunit 1 (human) that has had the initiator methionine removed. UniProtKB:P29083, 2-439.


A member of the class of piperidones that is piperidin-4-one substituted by a 3-oxoprop-1-en-3-yl group at position 1 and 4-nitrobenzylidene groups at positions 3 and 5. It is an inhibitor of ubiquitin-specific-processing protease 14 (USP14) and ubiquitin carboxyl-terminal hydrolase isozyme L5 (UCHL5).


name: positive regulation of nitric oxide-cGMP mediated signal transduction

description: Any process that increases the rate, frequency or extent of nitric oxide-cGMP mediated signal transduction.


name: positive regulation of cGMP-mediated signaling

description: Any process that increases the rate, frequency or extent of cGMP-mediated signaling.


name: negative regulation of nitric oxide-cGMP mediated signal transduction

description: Any process that decreases the rate, frequency or extent of nitric oxide-cGMP mediated signal transduction.


name: symbiont-mediated perturbation of host cGMP-mediated signal transduction

description: A process in which a symbiont alters or subverts a cGMP-mediated signal transduction pathway in its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.


name: negative regulation of cGMP-mediated signaling

description: Any process that decreases the rate, frequency or extent of cGMP-mediated signaling.


name: Y8487_DICDI Probable cyclin-dependent serine/threonine-protein kinase DDB_G0278487 (sprot)

description: A protein that is a translation product of the clkB gene in Dictyostelium discoideum.


name: cation channel sperm-associated auxiliary subunit epsilon isoform h3 (human)

description: A cation channel sperm-associated auxiliary subunit epsilon (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q5SY80-3.


name: AP-1 complex subunit mu-1 isoform 1 (rat)

description: An AP-1 complex subunit mu-1 isoform 1 that is encoded in the genome of rat.


kininogen-1 N-glycosylated 12 (human)

A kininogen-1 (human) that has been N-glycosylated at the residue equivalent to Asn-205 of the amino acid sequence represented by UniProtKB:P01042-1, in which the glycan composition is represented by GlyTouCan:G06247RL. Example: UniProtKB:P01042-1, Asn-205, MOD:00160~GNO:G06247RL.


kininogen-1 O-glycosylated 22 (human)

A kininogen-1 (human) that has been O-glycosylated at the residue equivalent to Thr-137 of the amino acid sequence represented by UniProtKB:P01042-1, in which the glycan composition is represented by GlyTouCan:G58001LT. Example: UniProtKB:P01042-1, Thr-137, MOD:00005~GNO:G58001LT.


kininogen-1 O-glycosylated 48 (human)

A kininogen-1 (human) that has been O-glycosylated at the residue equivalent to Thr-546 of the amino acid sequence represented by UniProtKB:P01042-1, in which the glycan composition is represented by GlyTouCan:G53434XO. Example: UniProtKB:P01042-1, Thr-546, MOD:00005~GNO:G53434XO.


kininogen-1 O-glycosylated 6 (human)

A kininogen-1 (human) that has been O-glycosylated at the residue equivalent to Ser-150 of the amino acid sequence represented by UniProtKB:P01042-1, in which the glycan composition is represented by GlyTouCan:G58001LT. Example: UniProtKB:P01042-1, Ser-150, MOD:00002~GNO:G58001LT.


kininogen-1 O-glycosylated 30 (human)

A kininogen-1 (human) that has been O-glycosylated at the residue equivalent to Thr-400 of the amino acid sequence represented by UniProtKB:P01042-1, in which the glycan composition is represented by GlyTouCan:G53434XO. Example: UniProtKB:P01042-1, Thr-400, MOD:00005~GNO:G53434XO.


kininogen-1 N-glycosylated 16 (human)

A kininogen-1 (human) that has been N-glycosylated at the residue equivalent to Asn-205 of the amino acid sequence represented by UniProtKB:P01042-1, in which the glycan composition is represented by GlyTouCan:G40926MX. Example: UniProtKB:P01042-1, Asn-205, MOD:00160~GNO:G40926MX.


kininogen-1 N-glycosylated 37 (human)

A kininogen-1 (human) that has been N-glycosylated at the residue equivalent to Asn-48 of the amino acid sequence represented by UniProtKB:P01042-1, in which the glycan composition is represented by GlyTouCan:G59626AS. Example: UniProtKB:P01042-1, Asn-48, MOD:00160~GNO:G59626AS.


kininogen-1 O-glycosylated 2 (human)

A kininogen-1 (human) that has been O-glycosylated at the residue equivalent to Ser-150 of the amino acid sequence represented by UniProtKB:P01042-1, in which the glycan composition is represented by GlyTouCan:G17015OC. Example: UniProtKB:P01042-1, Ser-150, MOD:00002~GNO:G17015OC.


kininogen-1 O-glycosylated 10 (human)

A kininogen-1 (human) that has been O-glycosylated at the residue equivalent to Ser-577 of the amino acid sequence represented by UniProtKB:P01042-1, in which the glycan composition is represented by GlyTouCan:G17015OC. Example: UniProtKB:P01042-1, Ser-577, MOD:00002~GNO:G17015OC.


kininogen-1 O-glycosylated 29 (human)

A kininogen-1 (human) that has been O-glycosylated at the residue equivalent to Thr-273 of the amino acid sequence represented by UniProtKB:P01042-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P01042-1, Thr-273, MOD:00005~GNO:G43417UB.


kininogen-1 N-glycosylated 4 (human)

A kininogen-1 (human) that has been N-glycosylated at the residue equivalent to Asn-169 of the amino acid sequence represented by UniProtKB:P01042-1, in which the glycan composition is represented by GlyTouCan:G27947YN. Example: UniProtKB:P01042-1, Asn-169, MOD:00160~GNO:G27947YN.


kininogen-1 O-glycosylated 33 (human)

A kininogen-1 (human) that has been O-glycosylated at the residue equivalent to Thr-401 of the amino acid sequence represented by UniProtKB:P01042-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P01042-1, Thr-401, MOD:00005~GNO:G43417UB.


kininogen-1 O-glycosylated 44 (human)

A kininogen-1 (human) that has been O-glycosylated at the residue equivalent to Thr-542 of the amino acid sequence represented by UniProtKB:P01042-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P01042-1, Thr-542, MOD:00005~GNO:G43417UB.


kininogen-1 O-glycosylated 5 (human)

A kininogen-1 (human) that has been O-glycosylated at the residue equivalent to Ser-150 of the amino acid sequence represented by UniProtKB:P01042-1, in which the glycan composition is represented by GlyTouCan:G53434XO. Example: UniProtKB:P01042-1, Ser-150, MOD:00002~GNO:G53434XO.


kininogen-1 O-glycosylated 43 (human)

A kininogen-1 (human) that has been O-glycosylated at the residue equivalent to Thr-533 of the amino acid sequence represented by UniProtKB:P01042-1, in which the glycan composition is represented by GlyTouCan:G53434XO. Example: UniProtKB:P01042-1, Thr-533, MOD:00005~GNO:G53434XO.


kininogen-1 isoform h3 (human)

A kininogen-1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P01042-3.


kininogen-1 N-glycosylated 30 (human)

A kininogen-1 (human) that has been N-glycosylated at the residue equivalent to Asn-294 of the amino acid sequence represented by UniProtKB:P01042-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P01042-1, Asn-294, MOD:00160~GNO:G43417UB.


kininogen-1 O-glycosylated 36 (human)

A kininogen-1 (human) that has been O-glycosylated at the residue equivalent to Thr-407 of the amino acid sequence represented by UniProtKB:P01042-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P01042-1, Thr-407, MOD:00005~GNO:G43417UB.


kininogen-1 N-glycosylated 38 (human)

A kininogen-1 (human) that has been N-glycosylated at the residue equivalent to Asn-48 of the amino acid sequence represented by UniProtKB:P01042-1, in which the glycan composition is represented by GlyTouCan:G88374WZ. Example: UniProtKB:P01042-1, Asn-48, MOD:00160~GNO:G88374WZ.


kininogen-1 N-glycosylated 29 (human)

A kininogen-1 (human) that has been N-glycosylated at the residue equivalent to Asn-294 of the amino acid sequence represented by UniProtKB:P01042-1, in which the glycan structure is represented by GlyTouCan:G42358LZ. Example: UniProtKB:P01042-1, Asn-294, MOD:00160~GNO:G42358LZ.


kininogen-1 O-glycosylated 8 (human)

A kininogen-1 (human) that has been O-glycosylated at the residue equivalent to Ser-531 of the amino acid sequence represented by UniProtKB:P01042-1, in which the glycan composition is represented by GlyTouCan:G73004SD. Example: UniProtKB:P01042-1, Ser-531, MOD:00002~GNO:G73004SD.


kininogen-1 N-glycosylated 27 (human)

A kininogen-1 (human) that has been N-glycosylated at the residue equivalent to Asn-294 of the amino acid sequence represented by UniProtKB:P01042-1, in which the glycan structure is represented by GlyTouCan:G36131WL. Example: UniProtKB:P01042-1, Asn-294, MOD:00160~GNO:G36131WL.


kininogen-1 N-glycosylated 1 (human)

A kininogen-1 (human) that has been N-glycosylated at the residue equivalent to Asn-169 of the amino acid sequence represented by UniProtKB:P01042-1, in which the glycan composition is represented by GlyTouCan:G00912UN. Example: UniProtKB:P01042-1, Asn-169, MOD:00160~GNO:G00912UN.


kininogen-1 O-glycosylated 31 (human)

A kininogen-1 (human) that has been O-glycosylated at the residue equivalent to Thr-400 of the amino acid sequence represented by UniProtKB:P01042-1, in which the glycan composition is represented by GlyTouCan:G57317CE. Example: UniProtKB:P01042-1, Thr-400, MOD:00005~GNO:G57317CE.


kininogen-1 N-glycosylated 11 (human)

A kininogen-1 (human) that has been N-glycosylated at the residue equivalent to Asn-205 of the amino acid sequence represented by UniProtKB:P01042-1, in which the glycan composition is represented by GlyTouCan:G00912UN. Example: UniProtKB:P01042-1, Asn-205, MOD:00160~GNO:G00912UN.


kininogen-1 O-glycosylated 27 (human)

A kininogen-1 (human) that has been O-glycosylated at the residue equivalent to Thr-151 of the amino acid sequence represented by UniProtKB:P01042-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P01042-1, Thr-151, MOD:00005~GNO:G43417UB.


kininogen-1 O-glycosylated 40 (human)

A kininogen-1 (human) that has been O-glycosylated at the residue equivalent to Thr-532 of the amino acid sequence represented by UniProtKB:P01042-1, in which the glycan composition is represented by GlyTouCan:G58001LT. Example: UniProtKB:P01042-1, Thr-532, MOD:00005~GNO:G58001LT.


kininogen-1 isoform LMW (human)

A kininogen-1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P01042-2.


kininogen-1 N-glycosylated 13 (human)

A kininogen-1 (human) that has been N-glycosylated at the residue equivalent to Asn-205 of the amino acid sequence represented by UniProtKB:P01042-1, in which the glycan composition is represented by GlyTouCan:G08293MJ. Example: UniProtKB:P01042-1, Asn-205, MOD:00160~GNO:G08293MJ.


kininogen-1 N-glycosylated 14 (human)

A kininogen-1 (human) that has been N-glycosylated at the residue equivalent to Asn-205 of the amino acid sequence represented by UniProtKB:P01042-1, in which the glycan composition is represented by GlyTouCan:G17015OC. Example: UniProtKB:P01042-1, Asn-205, MOD:00160~GNO:G17015OC.


kininogen-1 O-glycosylated 28 (human)

A kininogen-1 (human) that has been O-glycosylated at the residue equivalent to Thr-273 of the amino acid sequence represented by UniProtKB:P01042-1, in which the glycan composition is represented by GlyTouCan:G29068FM. Example: UniProtKB:P01042-1, Thr-273, MOD:00005~GNO:G29068FM.


kininogen-1 N-glycosylated 3 (human)

A kininogen-1 (human) that has been N-glycosylated at the residue equivalent to Asn-169 of the amino acid sequence represented by UniProtKB:P01042-1, in which the glycan composition is represented by GlyTouCan:G11115RO. Example: UniProtKB:P01042-1, Asn-169, MOD:00160~GNO:G11115RO.


kininogen-1 O-glycosylated 25 (human)

A kininogen-1 (human) that has been O-glycosylated at the residue equivalent to Thr-151 of the amino acid sequence represented by UniProtKB:P01042-1, in which the glycan composition is represented by GlyTouCan:G17015OC. Example: UniProtKB:P01042-1, Thr-151, MOD:00005~GNO:G17015OC.


kininogen-1 N-glycosylated 24 (human)

A kininogen-1 (human) that has been N-glycosylated at the residue equivalent to Asn-294 of the amino acid sequence represented by UniProtKB:P01042-1, in which the glycan composition is represented by GlyTouCan:G08293MJ. Example: UniProtKB:P01042-1, Asn-294, MOD:00160~GNO:G08293MJ.


kininogen-1 O-glycosylated 18 (human)

A kininogen-1 (human) that has been O-glycosylated at the residue equivalent to Thr-137 of the amino acid sequence represented by UniProtKB:P01042-1, in which the glycan composition is represented by GlyTouCan:G29068FM. Example: UniProtKB:P01042-1, Thr-137, MOD:00005~GNO:G29068FM.


kininogen-1 O-glycosylated 9 (human)

A kininogen-1 (human) that has been O-glycosylated at the residue equivalent to Ser-550 of the amino acid sequence represented by UniProtKB:P01042-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P01042-1, Ser-550, MOD:00002~GNO:G43417UB.


kininogen-1 O-glycosylated 45 (human)

A kininogen-1 (human) that has been O-glycosylated at the residue equivalent to Thr-542 of the amino acid sequence represented by UniProtKB:P01042-1, in which the glycan composition is represented by GlyTouCan:G53434XO. Example: UniProtKB:P01042-1, Thr-542, MOD:00005~GNO:G53434XO.


kininogen-1 O-glycosylated 17 (human)

A kininogen-1 (human) that has been O-glycosylated at the residue equivalent to Thr-137 of the amino acid sequence represented by UniProtKB:P01042-1, in which the glycan composition is represented by GlyTouCan:G23729WG. Example: UniProtKB:P01042-1, Thr-137, MOD:00005~GNO:G23729WG.


kininogen-1 O-glycosylated 46 (human)

A kininogen-1 (human) that has been O-glycosylated at the residue equivalent to Thr-546 of the amino acid sequence represented by UniProtKB:P01042-1, in which the glycan composition is represented by GlyTouCan:G29068FM. Example: UniProtKB:P01042-1, Thr-546, MOD:00005~GNO:G29068FM.


kininogen-1 O-glycosylated 15 (human)

A kininogen-1 (human) that has been O-glycosylated at the residue equivalent to Ser-604 of the amino acid sequence represented by UniProtKB:P01042-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P01042-1, Ser-604, MOD:00002~GNO:G43417UB.


kininogen-1 isoform HMW (human)

A kininogen-1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P01042-1.


name: kininogen-1, signal peptide removed phosphorylated form (human)

description: A kininogen-1 (human) that has had the signal peptide removed and that includes at least 1 phosphorylated residue. Example: UniProtKB:P01042-1, 19-644, MOD:00696.


kininogen-1 O-glycosylated 1 (human)

A kininogen-1 (human) that has been O-glycosylated at the residue equivalent to Ser-120 of the amino acid sequence represented by UniProtKB:P01042-1, in which the glycan composition is represented by GlyTouCan:G53434XO. Example: UniProtKB:P01042-1, Ser-120, MOD:00002~GNO:G53434XO.


kininogen-1 O-glycosylated 35 (human)

A kininogen-1 (human) that has been O-glycosylated at the residue equivalent to Thr-401 of the amino acid sequence represented by UniProtKB:P01042-1, in which the glycan composition is represented by GlyTouCan:G58001LT. Example: UniProtKB:P01042-1, Thr-401, MOD:00005~GNO:G58001LT.


kininogen-1 N-glycosylated 17 (human)

A kininogen-1 (human) that has been N-glycosylated at the residue equivalent to Asn-205 of the amino acid sequence represented by UniProtKB:P01042-1, in which the glycan composition is represented by GlyTouCan:G59626AS. Example: UniProtKB:P01042-1, Asn-205, MOD:00160~GNO:G59626AS.


kininogen-1 N-glycosylated 6 (human)

A kininogen-1 (human) that has been N-glycosylated at the residue equivalent to Asn-169 of the amino acid sequence represented by UniProtKB:P01042-1, in which the glycan composition is represented by GlyTouCan:G59626AS. Example: UniProtKB:P01042-1, Asn-169, MOD:00160~GNO:G59626AS.


kininogen-1 O-glycosylated 7 (human)

A kininogen-1 (human) that has been O-glycosylated at the residue equivalent to Ser-408 of the amino acid sequence represented by UniProtKB:P01042-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P01042-1, Ser-408, MOD:00002~GNO:G43417UB.


kininogen-1 O-glycosylated 26 (human)

A kininogen-1 (human) that has been O-glycosylated at the residue equivalent to Thr-151 of the amino acid sequence represented by UniProtKB:P01042-1, in which the glycan composition is represented by GlyTouCan:G29068FM. Example: UniProtKB:P01042-1, Thr-151, MOD:00005~GNO:G29068FM.


kininogen-1 O-glycosylated 39 (human)

A kininogen-1 (human) that has been O-glycosylated at the residue equivalent to Thr-532 of the amino acid sequence represented by UniProtKB:P01042-1, in which the glycan composition is represented by GlyTouCan:G53434XO. Example: UniProtKB:P01042-1, Thr-532, MOD:00005~GNO:G53434XO.


kininogen-1 N-glycosylated 10 (human)

A kininogen-1 (human) that has been N-glycosylated at the residue equivalent to Asn-169 of the amino acid sequence represented by UniProtKB:P01042-1, in which the glycan composition is represented by GlyTouCan:G99679NM. Example: UniProtKB:P01042-1, Asn-169, MOD:00160~GNO:G99679NM.


kininogen-1 N-glycosylated 32 (human)

A kininogen-1 (human) that has been N-glycosylated at the residue equivalent to Asn-294 of the amino acid sequence represented by UniProtKB:P01042-1, in which the glycan composition is represented by GlyTouCan:G59626AS. Example: UniProtKB:P01042-1, Asn-294, MOD:00160~GNO:G59626AS.


kininogen-1 N-glycosylated 2 (human)

A kininogen-1 (human) that has been N-glycosylated at the residue equivalent to Asn-169 of the amino acid sequence represented by UniProtKB:P01042-1, in which the glycan composition is represented by GlyTouCan:G06247RL. Example: UniProtKB:P01042-1, Asn-169, MOD:00160~GNO:G06247RL.


kininogen-1 N-glycosylated 26 (human)

A kininogen-1 (human) that has been N-glycosylated at the residue equivalent to Asn-294 of the amino acid sequence represented by UniProtKB:P01042-1, in which the glycan composition is represented by GlyTouCan:G27947YN. Example: UniProtKB:P01042-1, Asn-294, MOD:00160~GNO:G27947YN.


kininogen-1 O-glycosylated 49 (human)

A kininogen-1 (human) that has been O-glycosylated at the residue equivalent to Thr-571 of the amino acid sequence represented by UniProtKB:P01042-1, in which the glycan composition is represented by GlyTouCan:G23729WG. Example: UniProtKB:P01042-1, Thr-571, MOD:00005~GNO:G23729WG.


kininogen-1 N-glycosylated 15 (human)

A kininogen-1 (human) that has been N-glycosylated at the residue equivalent to Asn-205 of the amino acid sequence represented by UniProtKB:P01042-1, in which the glycan composition is represented by GlyTouCan:G27947YN. Example: UniProtKB:P01042-1, Asn-205, MOD:00160~GNO:G27947YN.


kininogen-1 O-glycosylated 21 (human)

A kininogen-1 (human) that has been O-glycosylated at the residue equivalent to Thr-137 of the amino acid sequence represented by UniProtKB:P01042-1, in which the glycan composition is represented by GlyTouCan:G57317CE. Example: UniProtKB:P01042-1, Thr-137, MOD:00005~GNO:G57317CE.


kininogen-1 O-glycosylated 13 (human)

A kininogen-1 (human) that has been O-glycosylated at the residue equivalent to Ser-604 of the amino acid sequence represented by UniProtKB:P01042-1, in which the glycan composition is represented by GlyTouCan:G23729WG. Example: UniProtKB:P01042-1, Ser-604, MOD:00002~GNO:G23729WG.


kininogen-1 N-glycosylated 23 (human)

A kininogen-1 (human) that has been N-glycosylated at the residue equivalent to Asn-294 of the amino acid sequence represented by UniProtKB:P01042-1, in which the glycan composition is represented by GlyTouCan:G06247RL. Example: UniProtKB:P01042-1, Asn-294, MOD:00160~GNO:G06247RL.


kininogen-1 O-glycosylated 38 (human)

A kininogen-1 (human) that has been O-glycosylated at the residue equivalent to Thr-532 of the amino acid sequence represented by UniProtKB:P01042-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P01042-1, Thr-532, MOD:00005~GNO:G43417UB.


kininogen-1 N-glycosylated 8 (human)

A kininogen-1 (human) that has been N-glycosylated at the residue equivalent to Asn-169 of the amino acid sequence represented by UniProtKB:P01042-1, in which the glycan composition is represented by GlyTouCan:G94917XT. Example: UniProtKB:P01042-1, Asn-169, MOD:00160~GNO:G94917XT.


kininogen-1 O-glycosylated 20 (human)

A kininogen-1 (human) that has been O-glycosylated at the residue equivalent to Thr-137 of the amino acid sequence represented by UniProtKB:P01042-1, in which the glycan composition is represented by GlyTouCan:G53434XO. Example: UniProtKB:P01042-1, Thr-137, MOD:00005~GNO:G53434XO.


kininogen-1 O-glycosylated 47 (human)

A kininogen-1 (human) that has been O-glycosylated at the residue equivalent to Thr-546 of the amino acid sequence represented by UniProtKB:P01042-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P01042-1, Thr-546, MOD:00005~GNO:G43417UB.


kininogen-1 O-glycosylated 19 (human)

A kininogen-1 (human) that has been O-glycosylated at the residue equivalent to Thr-137 of the amino acid sequence represented by UniProtKB:P01042-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P01042-1, Thr-137, MOD:00005~GNO:G43417UB.


kininogen-1 O-glycosylated 41 (human)

A kininogen-1 (human) that has been O-glycosylated at the residue equivalent to Thr-533 of the amino acid sequence represented by UniProtKB:P01042-1, in which the glycan composition is represented by GlyTouCan:G29068FM. Example: UniProtKB:P01042-1, Thr-533, MOD:00005~GNO:G29068FM.


kininogen-1 O-glycosylated 24 (human)

A kininogen-1 (human) that has been O-glycosylated at the residue equivalent to Thr-137 of the amino acid sequence represented by UniProtKB:P01042-1, in which the glycan composition is represented by GlyTouCan:G95678HJ. Example: UniProtKB:P01042-1, Thr-137, MOD:00005~GNO:G95678HJ.


kininogen-1 O-glycosylated 37 (human)

A kininogen-1 (human) that has been O-glycosylated at the residue equivalent to Thr-407 of the amino acid sequence represented by UniProtKB:P01042-1, in which the glycan composition is represented by GlyTouCan:G53434XO. Example: UniProtKB:P01042-1, Thr-407, MOD:00005~GNO:G53434XO.


kininogen-1 O-glycosylated 32 (human)

A kininogen-1 (human) that has been O-glycosylated at the residue equivalent to Thr-401 of the amino acid sequence represented by UniProtKB:P01042-1, in which the glycan composition is represented by GlyTouCan:G06247RL. Example: UniProtKB:P01042-1, Thr-401, MOD:00005~GNO:G06247RL.


kininogen-1 N-glycosylated 5 (human)

A kininogen-1 (human) that has been N-glycosylated at the residue equivalent to Asn-169 of the amino acid sequence represented by UniProtKB:P01042-1, in which the glycan composition is represented by GlyTouCan:G29068FM. Example: UniProtKB:P01042-1, Asn-169, MOD:00160~GNO:G29068FM.


kininogen-1 O-glycosylated 3 (human)

A kininogen-1 (human) that has been O-glycosylated at the residue equivalent to Ser-150 of the amino acid sequence represented by UniProtKB:P01042-1, in which the glycan composition is represented by GlyTouCan:G27947YN. Example: UniProtKB:P01042-1, Ser-150, MOD:00002~GNO:G27947YN.


kininogen-1 O-glycosylated 11 (human)

A kininogen-1 (human) that has been O-glycosylated at the residue equivalent to Ser-599 of the amino acid sequence represented by UniProtKB:P01042-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P01042-1, Ser-599, MOD:00002~GNO:G43417UB.


kininogen-1 O-glycosylated 14 (human)

A kininogen-1 (human) that has been O-glycosylated at the residue equivalent to Ser-604 of the amino acid sequence represented by UniProtKB:P01042-1, in which the glycan composition is represented by GlyTouCan:G29068FM. Example: UniProtKB:P01042-1, Ser-604, MOD:00002~GNO:G29068FM.


kininogen-1 N-glycosylated 21 (human)

A kininogen-1 (human) that has been N-glycosylated at the residue equivalent to Asn-205 of the amino acid sequence represented by UniProtKB:P01042-1, in which the glycan composition is represented by GlyTouCan:G94917XT. Example: UniProtKB:P01042-1, Asn-205, MOD:00160~GNO:G94917XT.


name: kininogen-1, signal peptide removed form (human)

description: A kininogen-1 (human) that has had the signal peptide removed. UniProtKB:P01042, 19-644.


kininogen-1 O-glycosylated 34 (human)

A kininogen-1 (human) that has been O-glycosylated at the residue equivalent to Thr-401 of the amino acid sequence represented by UniProtKB:P01042-1, in which the glycan composition is represented by GlyTouCan:G53434XO. Example: UniProtKB:P01042-1, Thr-401, MOD:00005~GNO:G53434XO.


kininogen-1 N-glycosylated 25 (human)

A kininogen-1 (human) that has been N-glycosylated at the residue equivalent to Asn-294 of the amino acid sequence represented by UniProtKB:P01042-1, in which the glycan composition is represented by GlyTouCan:G10486CT. Example: UniProtKB:P01042-1, Asn-294, MOD:00160~GNO:G10486CT.


kininogen-1 N-glycosylated 18 (human)

A kininogen-1 (human) that has been N-glycosylated at the residue equivalent to Asn-205 of the amino acid sequence represented by UniProtKB:P01042-1, in which the glycan composition is represented by GlyTouCan:G85144OK. Example: UniProtKB:P01042-1, Asn-205, MOD:00160~GNO:G85144OK.


kininogen-1 N-glycosylated 36 (human)

A kininogen-1 (human) that has been N-glycosylated at the residue equivalent to Asn-48 of the amino acid sequence represented by UniProtKB:P01042-1, in which the glycan composition is represented by GlyTouCan:G06247RL. Example: UniProtKB:P01042-1, Asn-48, MOD:00160~GNO:G06247RL.


kininogen-1 N-glycosylated 7 (human)

A kininogen-1 (human) that has been N-glycosylated at the residue equivalent to Asn-169 of the amino acid sequence represented by UniProtKB:P01042-1, in which the glycan composition is represented by GlyTouCan:G85144OK. Example: UniProtKB:P01042-1, Asn-169, MOD:00160~GNO:G85144OK.


kininogen-1 N-glycosylated 35 (human)

A kininogen-1 (human) that has been N-glycosylated at the residue equivalent to Asn-48 of the amino acid sequence represented by UniProtKB:P01042-1, in which the glycan composition is represented by GlyTouCan:G00912UN. Example: UniProtKB:P01042-1, Asn-48, MOD:00160~GNO:G00912UN.


kininogen-1 N-glycosylated 9 (human)

A kininogen-1 (human) that has been N-glycosylated at the residue equivalent to Asn-169 of the amino acid sequence represented by UniProtKB:P01042-1, in which the glycan composition is represented by GlyTouCan:G95678HJ. Example: UniProtKB:P01042-1, Asn-169, MOD:00160~GNO:G95678HJ.


kininogen-1 O-glycosylated 23 (human)

A kininogen-1 (human) that has been O-glycosylated at the residue equivalent to Thr-137 of the amino acid sequence represented by UniProtKB:P01042-1, in which the glycan composition is represented by GlyTouCan:G94917XT. Example: UniProtKB:P01042-1, Thr-137, MOD:00005~GNO:G94917XT.


kininogen-1 O-glycosylated 12 (human)

A kininogen-1 (human) that has been O-glycosylated at the residue equivalent to Ser-599 of the amino acid sequence represented by UniProtKB:P01042-1, in which the glycan composition is represented by GlyTouCan:G53434XO. Example: UniProtKB:P01042-1, Ser-599, MOD:00002~GNO:G53434XO.


kininogen-1 N-glycosylated 33 (human)

A kininogen-1 (human) that has been N-glycosylated at the residue equivalent to Asn-294 of the amino acid sequence represented by UniProtKB:P01042-1, in which the glycan composition is represented by GlyTouCan:G85144OK. Example: UniProtKB:P01042-1, Asn-294, MOD:00160~GNO:G85144OK.


kininogen-1 N-glycosylated 31 (human)

A kininogen-1 (human) that has been N-glycosylated at the residue equivalent to Asn-294 of the amino acid sequence represented by UniProtKB:P01042-1, in which the glycan composition is represented by GlyTouCan:G58001LT. Example: UniProtKB:P01042-1, Asn-294, MOD:00160~GNO:G58001LT.


kininogen-1 O-glycosylated 42 (human)

A kininogen-1 (human) that has been O-glycosylated at the residue equivalent to Thr-533 of the amino acid sequence represented by UniProtKB:P01042-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P01042-1, Thr-533, MOD:00005~GNO:G43417UB.


kininogen-1 N-glycosylated 22 (human)

A kininogen-1 (human) that has been N-glycosylated at the residue equivalent to Asn-294 of the amino acid sequence represented by UniProtKB:P01042-1, in which the glycan composition is represented by GlyTouCan:G00912UN. Example: UniProtKB:P01042-1, Asn-294, MOD:00160~GNO:G00912UN.


kininogen-1 N-glycosylated 19 (human)

A kininogen-1 (human) that has been N-glycosylated at the residue equivalent to Asn-205 of the amino acid sequence represented by UniProtKB:P01042-1, in which the glycan composition is represented by GlyTouCan:G86752LQ. Example: UniProtKB:P01042-1, Asn-205, MOD:00160~GNO:G86752LQ.


kininogen-1 N-glycosylated 20 (human)

A kininogen-1 (human) that has been N-glycosylated at the residue equivalent to Asn-205 of the amino acid sequence represented by UniProtKB:P01042-1, in which the glycan composition is represented by GlyTouCan:G88374WZ. Example: UniProtKB:P01042-1, Asn-205, MOD:00160~GNO:G88374WZ.


kininogen-1 O-glycosylated 4 (human)

A kininogen-1 (human) that has been O-glycosylated at the residue equivalent to Ser-150 of the amino acid sequence represented by UniProtKB:P01042-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P01042-1, Ser-150, MOD:00002~GNO:G43417UB.


kininogen-1 N-glycosylated 28 (human)

A kininogen-1 (human) that has been N-glycosylated at the residue equivalent to Asn-294 of the amino acid sequence represented by UniProtKB:P01042-1, in which the glycan composition is represented by GlyTouCan:G40926MX. Example: UniProtKB:P01042-1, Asn-294, MOD:00160~GNO:G40926MX.


kininogen-1 N-glycosylated 34 (human)

A kininogen-1 (human) that has been N-glycosylated at the residue equivalent to Asn-294 of the amino acid sequence represented by UniProtKB:P01042-1, in which the glycan composition is represented by GlyTouCan:G94917XT. Example: UniProtKB:P01042-1, Asn-294, MOD:00160~GNO:G94917XT.


name: ubiquitin receptor RAD23d isoform 1 (Arabidopsis thaliana)

description: A ubiquitin receptor RAD23d (Arabidopsis thaliana) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q84L30-1.


glucagon secreting cell

category: biolink:Cell biolink:AnatomicalEntity biolink:PhysicalEssence biolink:OrganismalEntity biolink:SubjectOfInvestigation biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: A cell that secretes glucagon.


type A cell of stomach

description: A type of enteroendocrine cell found in the stomach that secretes glucagon.


type A enteroendocrine cell

description: An enteroendocrine cell that produces glucagon.


name: choline O-acetyltransferase isoform B (fruit fly)

description: A choline O-acetyltransferase (fruit fly) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P07668-2.


name: CLAT_DROME Choline O-acetyltransferase (sprot)

description: A choline O-acetyltransferase that is encoded in the genome of fruit fly.


name: choline O-acetyltransferase isoform A (fruit fly)

description: A choline O-acetyltransferase (fruit fly) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P07668-1.


name: choline O-acetyltransferase isoform C (fruit fly)

description: A choline O-acetyltransferase (fruit fly) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P07668-3.


name: LRR receptor-like serine/threonine-protein kinase EFR phosphorylated 1 (Arabidopsis thaliana)

description: An LRR receptor-like serine/threonine-protein kinase EFR phosphorylated 1 in Arabidopsis thaliana.


name: neuromedin-K receptor phosphorylated 1 (human)

description: A neuromedin-K receptor (human) that has been phosphorylated on the residue at the position equivalent to Tyr-256 of the amino acid sequence represented by UniProtKB:P29371. UniProtKB:P29371, Tyr-256, MOD:00048.


name: versican core protein, signal peptide removed form (human)

description: A versican core protein (human) that has had the signal peptide removed. UniProtKB:P13611, 21-3396.


name: versican core protein, signal peptide removed form

description: A versican core protein that has had the signal peptide removed.


name: phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN sequence variant C124Y (human)

description: A phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN (human) that has a Tyr residue at the position equivalent to Cys-124 of the amino acid sequence represented by UniProtKB:P60484-1. Example: UniProtKB:P60484-1, Cys-124, CHEBI:46858.


name: parathyroid hormone/parathyroid hormone-related peptide receptor

description: A parathyroid hormone receptor that is a translation product of the human PTH1R gene or a 1:1 ortholog thereof.


parathyroid hormone receptor

A secretin-like G-protein coupled receptor that is a translation product of the human PTH1R or PTH2R genes, 1:1 orthologs thereof, or a semi-ortholog thereof.


parathyroid hormone 2 receptor

A parathyroid hormone receptor that is a translation product of the human PTH2R gene or a 1:1 ortholog thereof.


name: parathyroid hormone 2 receptor phosphorylated 1 (human)

description: A parathyroid hormone 2 receptor (human) that has been phosphorylated on the residue at the position equivalent to Ser-212 of the amino acid sequence represented by UniProtKB:P49190. UniProtKB:P49190, Ser-212, MOD:00046.


name: parathyroid hormone 2 receptor, signal peptide removed form (human)

description: A parathyroid hormone 2 receptor (human) that has had the signal peptide removed. UniProtKB:P49190, 25-550.


name: PTH1R_RAT Parathyroid hormone/parathyroid hormone-related peptide receptor (sprot)

description: A parathyroid hormone/parathyroid hormone-related peptide receptor that is encoded in the genome of rat.


name: PTH1R_HUMAN Parathyroid hormone/parathyroid hormone-related peptide receptor (sprot)

description: A parathyroid hormone/parathyroid hormone-related peptide receptor that is encoded in the genome of human.


name: PTH1R_MOUSE Parathyroid hormone/parathyroid hormone-related peptide receptor (sprot)

description: A parathyroid hormone/parathyroid hormone-related peptide receptor that is encoded in the genome of mouse.


name: PTH2R_HUMAN Parathyroid hormone 2 receptor (sprot)

description: A parathyroid hormone 2 receptor that is encoded in the genome of human.


name: PTH2R_RAT Parathyroid hormone 2 receptor (sprot)

description: A parathyroid hormone 2 receptor that is encoded in the genome of rat.


name: parathyroid hormone/parathyroid hormone-related peptide receptor isoform 1

description: A parathyroid hormone/parathyroid hormone-related peptide receptor that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P41593-1 or a 1:1 ortholog thereof.


name: parathyroid hormone/parathyroid hormone-related peptide receptor isoform 1 (rat)

description: A parathyroid hormone/parathyroid hormone-related peptide receptor isoform 1 that is encoded in the genome of rat.


name: PTH2R_MOUSE Parathyroid hormone 2 receptor (sprot)

description: A parathyroid hormone 2 receptor that is encoded in the genome of mouse.


name: parathyroid hormone/parathyroid hormone-related peptide receptor, signal peptide removed form (human)

description: A parathyroid hormone/parathyroid hormone-related peptide receptor (human) that has had the signal peptide removed. UniProtKB:Q03431, 27-593.


name: parathyroid hormone/parathyroid hormone-related peptide receptor isoform 1 (mouse)

description: A parathyroid hormone/parathyroid hormone-related peptide receptor isoform 1 that is encoded in the genome of mouse.


A53 Diffuse Large B-Cell Lymphoma

description: A genetic subtype of diffuse large B-cell lymphoma characterized by TP53 gene mutations and deletions that is often accompanied by aneuploidy.


Unresectable NUT Carcinoma

description: NUT carcinoma that is not amenable to surgical resection.


Lys-Thr-Trp-Gly-Lys-Asn-Leu-Val-Val

An oligopeptide composed of L-lysine, L-threonine, L-tryptophan, glycine, L-asparagine, L-leucine, L-valine and L-valine joined in sequence by peptide linkages; synthetic variant K9V of the yellow fever specific peptide epitope K9F.


Conjugate base of bhos#34-CoA


seizure protein 6 isoform 2 (mouse)

A seizure protein 6 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q7TSK2-2.


name: signal recognition particle subunit SRP72

description: A protein that is a translation product of the human SRP72 gene or a 1:1 ortholog thereof.


name: SRP72_DICDI Signal recognition particle subunit SRP72 (sprot)

description: A signal recognition particle subunit SRP72 that is encoded in the genome of Dictyostelium discoideum.


name: SRP72_SCHPO Signal recognition particle subunit srp72 (sprot)

description: A signal recognition particle subunit SRP72 that is encoded in the genome of Schizosaccharomyces pombe 972h-.


name: SRP72_CAEEL Signal recognition particle subunit SRP72 (sprot)

description: A signal recognition particle subunit SRP72 that is encoded in the genome of worm.


name: signal recognition particle subunit SRP72 phosphorylated 1 (human)

description: A signal recognition particle subunit SRP72 (human) that has been phosphorylated on the residue at the position equivalent to Thr-28 of the amino acid sequence represented by UniProtKB:O76094-1. Example: UniProtKB:O76094-1, Thr-28, MOD:00047.


name: signal recognition particle subunit SRP72 deaminated 1 (human)

description: A signal recognition particle subunit SRP72 (human) that has been deaminated on the residue at the position equivalent to Gln-107 of the amino acid sequence represented by UniProtKB:O76094-1. Example: UniProtKB:O76094-1, Gln-107, MOD:00685.


name: SRP72_HUMAN Signal recognition particle subunit SRP72 (sprot)

description: A signal recognition particle subunit SRP72 that is encoded in the genome of human.


name: signal recognition particle subunit SRP72 isoform h1 (human)

description: A signal recognition particle subunit SRP72 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O76094-1.


name: signal recognition particle subunit SRP72 isoform h2 (human)

description: A signal recognition particle subunit SRP72 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O76094-2.


name: signal recognition particle subunit SRP72 methylated 1 (human)

description: A signal recognition particle subunit SRP72 (human) that has been methylated on the residue at the position equivalent to Cys-323 of the amino acid sequence represented by UniProtKB:O76094-1. Example: UniProtKB:O76094-1, Cys-323, MOD:00660.


name: SRP72_YEAST Signal recognition particle subunit SRP72 (sprot)

description: A signal recognition particle subunit SRP72 that is encoded in the genome of yeast.


phenyl N-(methylsulfonyl)imidoformate

An N-sulfonylimidate compound having S-methyl and O-phenyl substituents.


spindle cell nevus

description: A nevus characterized by the presence of spindle-shaped melanocytes.


name: DNA mismatch repair protein Msh6 methylated 1 (human)

description: A DNA mismatch repair protein Msh6 (human) that has been methylated on the residue at the position equivalent to Cys-1241 of the amino acid sequence represented by UniProtKB:P52701-1. Example: UniProtKB:P52701-1, Cys-1241, MOD:00660.


name: Na(+)/H(+) exchange regulatory cofactor NHE-RF1 isoform 1 (rat)

description: A Na(+)/H(+) exchange regulatory cofactor NHE-RF1 isoform 1 that is encoded in the genome of rat.


name: Childhood Recurrent Malignant Solid Neoplasm

description: The reemergence of a childhood malignant solid neoplasm after a period of remission.


aspartate--ammonia ligase

A protein that is a translation product of the Escherichia coli K-12 asnA gene or a 1:1 ortholog thereof.


name: ASNA_ECOLI Aspartate--ammonia ligase (sprot)

description: An aspartate--ammonia ligase that is encoded in the genome of Escherichia coli K-12.


amelogenesis imperfecta type 2A1

description: Any amelogenesis imperfecta in which the cause of the disease is a mutation in the KLK4 gene.


name: receptor-type tyrosine-protein kinase FLT3 sequence variant D839G, signal peptide removed form (human)

description: A receptor-type tyrosine-protein kinase FLT3 (human) that has a Gly residue at the position equivalent to Asp-839 of the amino acid sequence represented by UniProtKB:P36888-1 and that has had the signal peptide removed. Example: UniProtKB:P36888-1, 27-993, Asp-839, CHEBI:29947.


name: RNA-binding protein 48 isoform 1 (mouse)

description: An RNA-binding protein 48 isoform 1 that is encoded in the genome of mouse.


name: adhesion G-protein coupled receptor D1 isoform h1 (human)

description: An adhesion G-protein coupled receptor D1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q6QNK2-1.


name: transcription factor E4F1 methylated 2 (human)

description: A transcription factor E4F1 (human) that has been methylated on the residue at the position equivalent to Cys-225 of the amino acid sequence represented by UniProtKB:Q66K89. UniProtKB:Q66K89, Cys-225, MOD:00660.


An organoammonium salt resulting from the mixing of equimolar amounts of GGTI-2133 free base and trifluoroacetic acid. An inhibitor of geranylgeranyltransferase type I.


name: RER1_ARATH Protein RETICULATA-RELATED 1, chloroplastic (sprot)

description: A protein that is a translation product of the RER1 gene in Arabidopsis thaliana.


name: positive regulation of triglyceride catabolic process

description: Any process that increases the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of triglyceride.


name: positive regulation of triglyceride metabolic process

description: Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving triglyceride, any triester of glycerol.


name: positive regulation of triglyceride biosynthetic process

description: Any process that increases the rate, frequency, or extent of triglyceride biosynthesis. Triglyceride biosynthesis is the collection of chemical reactions and pathways resulting in the formation of triglyceride, any triester of glycerol.


name: lysophospholipase D GDPD3 isoform h1 (human)

description: A lysophospholipase D GDPD3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q7L5L3-2.


specific developmental disorder

description: A developmental disorder of mental health that categorizes specific learning disabilities and developmental disorders affecting coordination.


conduct disorder

description: A disorder diagnosed in childhood or adolescence age group characterized by aggressive behavior, deceitfulness, destruction of property or violation of rules that is persistent and repetitive, and within a one year period.


communication disorder

description: A disorder characterized by an individual's inability to comprehend or share ideas or feelings because of an impairment in language, speech, or hearing.


name: attention deficit-hyperactivity disorder 8


specific language impairment

description: A language disorder characterized by difficulty in language acquisition despite otherwise normal development and in the absence of any obvious explanatory factors.


fetal alcohol syndrome

description: Fetal alcohol syndrome (FAS) is a rare malformation syndrome caused by excessive maternal consumption of alcohol during pregnancy. It is characterized by prenatal and/or postnatal growth deficiency (weight and/or height <10th percentile), a unique cluster of minor facial anomalies (short palpebral fissures, flat and smooth philtrum, and thin upper lip) and severe central nervous system (CNS) abnormalities including microcephaly, and cognitive and behavioral impairment (intellectual disability, deficit in general cognition, learning and language, executive function, visual-spatial processing, memory, and attention).


tic disorder

description: Disorders characterized by recurrent TICS that may interfere with speech and other activities. Tics are sudden, rapid, nonrhythmic, stereotyped motor movements or vocalizations which may be exacerbated by stress and are generally attenuated during absorbing activities. Tic disorders are distinguished from conditions which feature other types of abnormal movements that may accompany another another condition. (From DSM-IV, 1994)


learning disability

description: A group of disorders that affect a person's ability to learn or process specific types of information which is in contrast to his/her apparent level of intellect.


developmental coordination disorder

description: A disorder characterized by an impairment in the development of an individual's motor coordination skills; this impairment in motor development is not due to a medical condition.


Tourette syndrome

description: A neurologic disorder caused by defective metabolism of the neurotransmitters in the brain. It is characterized by repeated involuntary movements (motor tics) and uncontrollable vocal sounds (vocal tics). The symptoms are usually manifested before the age of eighteen.


name: mixed receptive-expressive language disorder

description: A disorder characterized by an impairment in the development of an individual's expressive and receptive language capabilities which is in contrast to his/her nonverbal intellect. The impairment may be acquired (i.e., due to a brain lesion or head trauma) or developmental (i.e., no known neurological insult).


transient tic disorder

description: A neurological disorder presenting in childhood that is characterized by motor and/or phonic tics that occur daily or nearly daily for one to twelve months and are not attributed to an identifiable cause.


articulation disorder

description: A disorder characterized by the failure to use developmentally expected speech sounds that are appropriate for the individual's age (i.e., the individual makes errors in sound production or use or omits sounds such as final consonants).


partial fetal alcohol syndrome

description: A fetal alcohol spectrum disorder that results in most, but not all, of the growth deficiency and/or craniofacial features of fetal alcohol syndrome including central nervous system dysfunction due to prenatal alcohol exposure.


dysgraphia

description: Loss or impairment of the ability to write (letters, syllables, words, or phrases) due to an injury to a specific cerebral area or occasionally due to emotional factors. This condition rarely occurs in isolation, and often accompanies aphasia. (From Adams et al., Principles of Neurology, 6th ed, p485; apa, Thesaurus of Psychological Index Terms, 1994)


specific language impairment 5

description: A communication disorder that involves the processing of linguistic information.


dyslexia

description: A learning disorder characterized by an impairment in processing written words. Reading difficulties can include distortions, omissions or substitutions of characters. Oral and silent reading difficulties can include faulty and slow comprehension.


description: A disorder characterized by a marked pattern of inattention and/or hyperactivity-impulsivity that is inconsistent with developmental level and clearly interferes with functioning in at least two settings (e.g. at home and at school). When present, the symptoms of hyperactivity are most often present before the age of 7 years. There are three recognized presentations or subtypes from most to least common: combined type, inattentive/distractible type, hyperactive/impulsive type.


fetal nicotine spectrum disorder

description: A specific developmental disorder that is characterized by physical, behavioral and learning birth defects resulting from maternal ingestion of nicotine during pregnancy.


writing disorder

description: A learning disability that involves impaired written language ability such as impairments in handwriting, spelling, organization of ideas, and composition.


expressive language disorder

description: A disorder characterized by an impairment in the development of an individual's expressive language which is in contrast to his/her nonverbal intellect and receptive language development. The impairment may be acquired (i.e., due to a brain lesion or head trauma) or developmental (i.e., no known neurological insult).


chronic tic disorder

description: A neurological disorder presenting in childhood that is characterized by either motor or phonic tics, but not both, that occur daily or nearly daily for at least a year and are not attributed to an identifiable cause.


alcohol-related birth defect

description: A physical or cognitive mental abnormality caused by maternal alcohol consumption and its toxic effect on the developing embryo during pregnancy.


fetal alcohol spectrum disorder

description: A group of disorders caused by a prenatal exposure to maternal consumption of alcohol leading to a range of behavioral, cognitive and neurological deficits in the offspring. It is characterized by physical growth problems, distinct facies, and varying psycho-neurological issues.


name: hereditary attention deficit-hyperactivity disorder

description: An instance of attention deficit-hyperactivity disorder that is caused by an inherited genomic modification in an individual.


name: neurobehavioral disorder with prenatal alcohol exposure

description: A fetal alcohol spectrum disorder that is characterized by one or more deficits in neurocognition and in self-regulation plus two or more deficits in adaptive functioning, with at least 1 in communication or social communication and interaction.


name: kinesin-like protein Klp98A isoform A (fruit fly)

description: A kinesin-like protein Klp98A (fruit fly) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9VB25-1.


name: DMD3_CAEEL Doublesex- and mab-3-related transcription factor dmd-3 (sprot)

description: A protein that is a translation product of the dmd-3 gene in worm.


name: doublesex- and mab-3-related transcription factor dmd-3 isoform a (worm)

description: A doublesex- and mab-3-related transcription factor dmd-3 (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9XWN9-1.


name: doublesex- and mab-3-related transcription factor dmd-3 isoform b (worm)

description: A doublesex- and mab-3-related transcription factor dmd-3 (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9XWN9-2.


name: BRO1_SCHPO Vacuolar protein-sorting protein bro1 (sprot)

description: A programmed cell death 6-interacting protein that is encoded in the genome of Schizosaccharomyces pombe 972h-.


SAVININ

A lignan that is dihydrofuran-2(3H)-one (gamma-butyrolactone) substituted by a 1,3-benzodioxol-5-ylmethylidene group at position 3 and a 1,3-benzodioxol-5-ylmethyl group at position 4 (the 3E,4R-isomer). It exhibits antiviral activity against SARS-CoV-2.


roundabout homolog 1 isoform h1 (human)

A roundabout homolog 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9Y6N7-1.


name: procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 deaminated 1 (human)

description: A procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 (human) that has been deaminated on the residue at the position equivalent to Asn-725 of the amino acid sequence represented by UniProtKB:O00469-1. Example: UniProtKB:O00469-1, Asn-725, MOD:00684.


name: high affinity immunoglobulin gamma Fc receptor I isoform h2 (human)

description: A high affinity immunoglobulin gamma Fc receptor I (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P12314-2.


name: FBK93_ARATH Putative F-box/kelch-repeat protein At4g34170 (sprot)

description: A protein that is a translation product of the At4g34170 gene in Arabidopsis thaliana.


name: EP1 subtype prostaglandin E2 receptor binding

category: biolink:MolecularActivity biolink:Occurrent biolink:OntologyClass biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: Binding to an EP1 subtype prostaglandin E2 receptor.


olfactory receptor 10G2

A class II olfactory receptor that is a translation product of the human OR10G2 gene or a 1:1 ortholog thereof.


name: O10G2_HUMAN Olfactory receptor 10G2 (sprot)

description: An olfactory receptor 10G2 that is encoded in the genome of human.


nectin-4 isoform m1 (mouse)

A nectin-4 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8R007-1.


name: inositol 1,4,5-trisphosphate receptor type 1 isoform r2 (rat)

description: An inositol 1,4,5-trisphosphate receptor type 1 (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P29994-2.


name: Testicular Mixed Embryonal Carcinoma and Yolk Sac Tumor with Seminoma

description: A malignant germ cell tumor arising from the testis.  It is characterized by a mixture of embryonal carcinoma, yolk sac, and seminomatous morphologic elements.  Patients may present with painless or painful testicular swelling.


name: cytochrome c, initiator methionine removed N6-acetyllysine form (human)

description: A cytochrome c (human) that has had the initiator methionine removed and that includes at least 1 N6-acetyllysine. UniProtKB:P99999, 2-105, MOD:00064.


name: Refractory Primary Cutaneous CD8-Positive Aggressive Epidermotropic Cytotoxic T-Cell Lymphoma

description: Primary cutaneous CD8-positive aggressive epidermotropic cytotoxic T-cell lymphoma that is resistant to treatment.


name: Stage III Childhood Non-Hodgkin Lymphoma by Toronto Guidelines v2

description: Tumors (extranodal) or nodal areas on both sides (above and below) of the diaphragm or any primary intrathoracic tumors (mediastinal, hilar, pulmonary, pleural, or thymic) or extensive (unresectable) primary intra-abdominal disease or any paraspinal or epidural tumors regardless of other tumor sites. (Childhood cancer staging for population registries according to the Toronto Childhood Cancer Stage Guidelines - Version 2. Cancer Council Queensland and Cancer Australia: Brisbane, Australia; 2021.)


name: Lugano Classification Advanced Stage Adult Non-Hodgkin Lymphoma AJCC v8

description: Advanced stage adult non-Hodgkin lymphoma based on the Lugano classification criteria. It includes stages III and IV. (from AJCC 8th Ed.)


Advanced Non-Hodgkin Lymphoma

description: Non-Hodgkin lymphoma that has spread extensively to other anatomic sites or is no longer responding to treatment.


Stage I Diffuse Large B-Cell Lymphoma

description: Ann Arbor Classification: Stage I: Involvement of a single lymph node region (I); or localized involvement of a single extralymphatic organ or site in the absence of any lymph node involvement (IE).


name: Helicobacter Pylori-Associated Gastric Mucosa-Associated Lymphoid Tissue Lymphoma

description: A low grade, indolent B-cell lymphoma that is associated with Helicobacter pylori infection.


Intestinal T-cell lymphoma recurrent

description: The reemergence of enteropathy-associated T-cell lymphoma after a period of remission.


name: Adult T-Cell Leukemia/Lymphoma by Ann Arbor Stage

description: An anatomic stage for adult T-cell leukemia/lymphoma based on the Ann Arbor classification criteria.


name: Mycosis Fungoides and Sezary Syndrome by AJCC v7 Stage

description: A term that refers to the staging of mycosis fungoides and Sezary syndrome, following the rules of the TNM AJCC v7 classification system.


name: Primary Cutaneous B-Cell Non-Hodgkin Lymphoma

description: A B-cell non-Hodgkin lymphoma arising from the skin.  Representative examples include cutaneous marginal zone B-cell lymphoma and cutaneous follicle center lymphoma.


name: Refractory EBV-Positive Diffuse Large B-Cell Lymphoma, Not Otherwise Specified

description: EBV-positive diffuse large B-cell lymphoma, not otherwise specified that is resistant to treatment.


name: Central Nervous System Anaplastic Large Cell Lymphoma, ALK-Negative

description: An anaplastic large cell lymphoma, ALK-negative, arising from the central nervous system.


name: Stage IV Childhood Lymphoblastic Lymphoma

description: Stage IV: Tumors involve bone marrow and/or central nervous system (CNS) regardless of other sites of involvement (from PDQ).


name: Stage IVA1 Mycosis Fungoides and Sezary Syndrome AJCC v8

description: Stage IVA1 includes: T1-4, N0-2, M0, B2. T1: Limited patches, papules, and/or plaques covering less than 10% of the skin surface. T2: Patches, papules, or plaques covering 10% or more of the skin surface. T3: One or more tumors (equal or greater than 1 cm in diameter). T4: Confluence of erythema covering 80% or more of body surface area. N0: No clinically abnormal peripheral lymph nodes; biopsy not required. N1: Clinically abnormal peripheral lymph nodes; histopathology Dutch grade 1 or National Cancer Institute (NCI) LN0-2. N2: Clinically abnormal peripheral lymph nodes; histopathology Dutch grade 2 or NCI LN3. M0: No visceral organ involvement. B2: High blood tumor burden: 1,000 per microliter or more Sezary cells with positive clone. (AJCC 8th ed.)


Adult Burkitt Lymphoma

description: A Burkitt lymphoma occurring in adults.


Advanced Follicular Lymphoma

description: Follicular lymphoma that has spread extensively to other anatomic sites or is no longer responding to treatment.


Recurrent Transformed Mycosis Fungoides

description: The reemergence of transformed mycosis fungoides after a period of remission.


Grade 1 Cutaneous Follicular Lymphoma

description: A cutaneous lymphoma which contains up to 5 centroblasts per 40X high-power microscopic field.


name: Recurrent Diffuse Large B-Cell Lymphoma Associated with Chronic Inflammation

description: The reemergence of diffuse large B-cell lymphoma associated with chronic inflammation after a period of remission.


name: Primary mediastinal large B-cell lymphoma stage IV

description: Ann Arbor Classification: Stage IV: Diffuse or disseminated involvement of one or more extralymphatic organs, with or without associated lymph node involvement; or isolated extralymphatic organ involvement in the absence of adjacent regional lymph node involvement, but in conjunction with disease in distant site(s); or any involvement of the liver or bone marrow, lungs (other than by direct extension from another site), or cerebrospinal fluid.


Centroblastic lymphoma stage II

description: Ann Arbor Classification: Stage II: Involvement of two or more lymph node regions on the same side of the diaphragm (II); or localized involvement of a single extralymphatic organ or site in association with regional lymph node involvement with or without involvement of other lymph node regions on the same side of the diaphragm (IIE). The number of regions involved may be indicated by a subscript (e.g., II3).


name: Recurrent Breast Implant-Associated Anaplastic Large Cell Lymphoma

description: The reemergence of breast implant-associated anaplastic large cell lymphoma after a period of remission.


Primary Cutaneous Non-Hodgkin Lymphoma

description: A B-or T-cell non-Hodgkin lymphoma arising in the skin.


name: Lugano Classification Stage II Adult Non-Hodgkin Lymphoma AJCC v8

description: Stage II: Involvement of two or more lymph node regions on the same side of the diaphragm. (from AJCC 8th Ed.)


name: Lung Intravascular Large B-Cell Lymphoma

description: An aggressive extranodal B-cell non-Hodgkin lymphoma that affects the lung.  It is characterized by the presence of large neoplastic lymphocytes exclusively in the lumina of small vessels, particularly capillaries.


Transformed Mycosis Fungoides

description: Histologic transformation of mycosis fungoides to an aggressive non-Hodgkin lymphoma.


Adult Lymphoblastic Lymphoma

description: A lymphoblastic lymphoma occurring in adults.


name: Mycosis fungoides/Sezary syndrome stage I

description: Stage I includes: IA (T1, N0, M0, B0-1); IB (T2, N0, M0, B0-1). T1: Limited patches, papules, and/or plaques covering less than 10% of the skin surface.  May further stratify into T1a (patch only) vs. T1b (plaque +/- patch).  T2: Patches, papules, or plaques covering 10% or more of the skin surface.  May further stratify into T2a (patch only) vs. T2b (plaque +/- patch).  N0: No clinically abnormal peripheral lymph nodes; biopsy not required.  M0: No visceral organ involvement.  B0: Absence of significant blood involvement: 5% or less of peripheral blood lymphocytes are atypical (Sezary cells).  B1: Low blood tumor burden: more than 5% of peripheral blood lymphocytes are atypical (Sezary cells) but does not meet the criteria of B2.  (AJCC 7th ed.)


name: Ann Arbor Stage II Subdiaphragmatic Nodular Lymphocyte Predominant B-Cell Lymphoma


name: Refractory High Grade B-Cell Lymphoma with MYC, BCL2, and BCL6 Rearrangements

description: High-grade B-cell lymphoma with MYC, BCL2, and BCL6 rearrangements that is resistant to treatment.


name: Ann Arbor Stage IV Grade 2 Follicular Lymphoma


grade 3A follicular lymphoma

description: A grade 3 follicular lymphoma in which centrocytes are present.


Refractory Grade 1 Follicular Lymphoma

description: Grade 1 follicular lymphoma that is resistant to treatment.


name: Refractory Primary Vitreoretinal Non-Hodgkin Lymphoma

description: Primary vitreoretinal non-Hodgkin lymphoma that does not respond to treatment.


Recurrent Adult Immunoblastic Lymphoma

description: The reemergence of adult immunoblastic lymphoma after a period of remission.


name: Follicle center lymphoma, follicular grade I, II, III stage IV


name: Childhood Primary Cutaneous Anaplastic Large Cell Lymphoma

description: An anaplastic large cell lymphoma that occurs during childhood and is limited to the skin at the time of diagnosis.


Follicular lymphoma stage I

description: Ann Arbor Classification: Stage I: Involvement of a single lymph node region (I); or localized involvement of a single extralymphatic organ or site in the absence of any lymph node involvement (IE).


name: Colorectal High Grade B-Cell Lymphoma, Not Otherwise Specified

description: High-grade B-cell lymphoma, not otherwise specified, that arises from the colorectal region.


description: Lymphoplasmacytic lymphoma resistant to treatment.


Indolent T-Cell Non-Hodgkin Lymphoma

description: A T-cell non-Hodgkin lymphoma with an indolent clinical course.


name: Precursor B-lymphoblastic lymphoma stage II

description: Ann Arbor Classification: Stage II: Involvement of two or more lymph node regions on the same side of the diaphragm (II); or localized involvement of a single extralymphatic organ or site in association with regional lymph node involvement with or without involvement of other lymph node regions on the same side of the diaphragm (IIE).


non-Hodgkin's lymphoma of spleen

description: Non-Hodgkin lymphoma involving the spleen.


name: Primary Ciliary Body Non-Hodgkin Lymphoma

description: An extremely rare low-grade B-cell non-Hodgkin lymphoma that arises from the ciliary body. It is characterized by the presence of a diffuse infiltrate of small, round lymphocytes. Most cases represent extranodal marginal zone lymphomas of mucosa-associated lymphoid tissue.


name: Mantle Cell Lymphoma with CCND3 Rearrangement

description: Mantle cell lymphoma characterized by the presence of CCND3 gene rearrangement. A small number of cases express this gene rearrangement and not CCND1 gene rearrangement.


name: Ann Arbor Stage II Grade 3 Follicular Lymphoma


name: Cutaneous Nasal Type Extranodal NK/T-Cell Lymphoma

description: Nasal type extranodal NK/T-cell lymphoma affecting the skin.


name: Head and Neck Large B-Cell Lymphoma with IRF4 Rearrangement

description: A large B-cell lymphoma with IRF4 rearrangement that arises from the head and neck region, usually the Waldeyer ring and/or cervical lymph nodes.


name: Methotrexate-Associated Diffuse Large B-Cell Lymphoma

description: A diffuse large B-cell lymphoma that develops in patients who are immunosuppressed with methotrexate.


name: Stage IIIA Mycosis Fungoides and Sezary Syndrome AJCC v7

description: Stage IIIA includes: T4, N0-2, M0, B0.  T4: Confluence of erythema covering 80% or more of body surface area.  N0: No clinically abnormal peripheral lymph nodes; biopsy not required.  N1: Clinically abnormal peripheral lymph nodes; histopathology Dutch grade 1 or NCI LN0-2.  N2: Clinically abnormal peripheral lymph nodes; histopathology Dutch grade 2 or NCI LN3.  M0: No visceral organ involvement.  B0: Absence of significant blood involvement: 5% or less of peripheral blood lymphocytes are atypical (Sezary cells).  (AJCC 7th ed.)


name: Recurrent Primary Cutaneous Anaplastic Large Cell Lymphoma

description: The reemergence of primary cutaneous anaplastic large cell lymphoma after a period of remission.


Tonsillar Diffuse Large B-Cell Lymphoma

description: Diffuse large B-cell lymphoma that affects the tonsil and the bulk of the tumor is in this anatomic area.