lipopolysaccharide metabolic process

description: The chemical reactions and pathways involving lipopolysaccharides, a group of related, structurally complex components of the outer membrane of Gram-negative bacteria. Lipopolysaccharides consist three covalently linked regions, lipid A, core oligosaccharide, and an O side chain. Lipid A is responsible for the toxicity of the lipopolysaccharide.


name: induction by symbiont of tumor or growth in host

category: biolink:BiologicalProcess biolink:Occurrent biolink:OntologyClass biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: The process in which a symbiont causes the formation of a mass of cells in a host organism. While these growths are often called nodules, they are not formed as nitrogen-fixing structures, but rather to provide an environment for the symbiont to grow. In this sense they are parasitic structures rather than mutualistic.


name: positive regulation of monoatomic ion transmembrane transport

description: Any process that activates or increases the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other.


histone H4R3 methyltransferase activity

category: biolink:MolecularActivity biolink:Occurrent biolink:OntologyClass biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: Catalysis of the reaction: S-adenosyl-L-methionine + (histone H4)-arginine (position 3) = S-adenosyl-L-homocysteine + (histone H4)-N-methyl-arginine (position 3). This reaction is the addition of a methyl group to the arginine residue at position 3 of histone H4, producing histone H4R3me.


name: positive regulation of microglial cell mediated cytotoxicity

description: Any process that activates or increases the frequency, rate or extent of microglial cell mediated cytotoxicity.


peptidyl-arginine omega-N-methylation

description: The addition of a methyl group onto a terminal nitrogen (omega nitrogen) atom of an arginine residue in a protein.


name: 3',5'-cyclic diguanylic acid metabolic process

description: The chemical reactions and pathways involving 3',5'-cyclic diguanylic acid, a cyclic purine dinucleotide in which the base groups are guanine.


cuproptosis

description: A programmed cell death process that is induced by intracellular copper accumulation.


description: Catalysis of the reaction: 2 farnesyl diphosphate = diphosphate + presqualene diphosphate.


name: G protein-coupled photoreceptor activity

description: Combining with incidental electromagnetic radiation, particularly visible light, and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.


name: ubiquinone biosynthetic process from chorismate

description: The chemical reactions and pathways resulting in the formation of ubiquinone, beginning with the conversion of chorismate to 4-hydroxybenzoate.


CDP catabolic process

description: The chemical reactions and pathways resulting in the breakdown of CDP, cytidine (5'-)diphosphate.


name: inorganic cation transmembrane transporter activity

description: Enables the transfer of inorganic cations from one side of a membrane to the other. Inorganic cations are atoms or small molecules with a positive charge that do not contain carbon in covalent linkage.


MHC class I receptor activity

description: Combining with an MHC class I protein complex to initiate a change in cellular activity. Class I here refers to classical class I molecules.


name: cellular response to differentiation-inducing factor 1

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one stimulus.


name: enzyme-linked receptor protein signaling pathway

category: biolink:Pathway biolink:OntologyClass biolink:BiologicalProcess biolink:Occurrent biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: The series of molecular signals initiated by an extracellular ligand binding to a receptor on the surface of the target cell, where the receptor possesses catalytic activity or is closely associated with an enzyme such as a protein kinase, and ending with the regulation of a downstream cellular process, e.g. transcription.


name: symbiont-mediated perturbation of host vesicle-mediated transport

description: A process in which a symbiont alters or subverts vesicle-mediated transport in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.


name: negative regulation of neuroinflammatory response

description: Any process that stops, prevents or reduces the frequency, rate or extent of neuroinflammatory response.


sarcomerogenesis

description: The process in which sarcomeres are added in series within a fiber.


reproductive behavior

description: The specific behavior of an organism that is associated with reproduction.


name: regulation of anthocyanin metabolic process

description: Any process that modulates the frequency, rate or extent of chemical reactions and pathways involving anthocyanins.


prephenate(2-) metabolic process

description: The chemical reactions and pathways involving prephenate(2-).


name: positive regulation of platelet formation

description: Any process that activates or increases the frequency, rate or extent of platelet formation.


regulation of fibroblast chemotaxis

description: Any process that modulates the frequency, rate or extent of fibroblast chemotaxis.


emericellamide A catabolic process

description: The chemical reactions and pathways resulting in the breakdown of emericellamide A.


name: negative regulation of serotonin biosynthetic process

description: Any process that stops, prevents or reduces the frequency, rate or extent of serotonin biosynthetic process.


regulation of signaling

description: Any process that modulates the frequency, rate or extent of a signaling process.


beta-caryophyllene catabolic process

description: The chemical reactions and pathways resulting in the breakdown of beta-caryophyllene.


name: organophosphate ester transmembrane transporter activity

description: Enables the transfer of organophosphate esters from one side of a membrane to the other. Organophosphate esters are small organic molecules containing phosphate ester bonds.


name: reactive oxygen species metabolic process

description: The chemical reactions and pathways involving a reactive oxygen species, any molecules or ions formed by the incomplete one-electron reduction of oxygen. They contribute to the microbicidal activity of phagocytes, regulation of signal transduction and gene expression, and the oxidative damage to biopolymers.


aminoacyltransferase activity

description: Catalysis of the transfer of an amino-acyl group from one compound (donor) to another (acceptor).


cytokine production

description: The appearance of a cytokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


name: NAD-dependent protein lysine deacetylase activity

description: Catalysis of the reaction: N(6)-acetyl-L-lysyl-[protein] + NAD+ + H2O = L-lysyl-[protein] + 2''-O-acetyl-ADP-D-ribose + nicotinamide.


name: regulation of interleukin-17-mediated signaling pathway

description: Any process that modulates the frequency, rate or extent of interleukin-17-mediated signaling pathway.


nitric oxide catabolic process

description: The chemical reactions and pathways resulting in the breakdown of nitric oxide, nitrogen monoxide (NO), a colorless gas only slightly soluble in water.


name: regulation of cellular response to growth factor stimulus

description: Any process that modulates the rate, frequency, or extent of a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth factor stimulus.


interleukin-25 receptor activity

description: Combining with interleukin-25 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


name: intracellular monoatomic ion homeostasis

description: A homeostatic process involved in the maintenance of a steady state level of monoatomic ions within a cell. Monatomic ions (also called simple ions) are ions consisting of exactly one atom.


description: Catalysis of the reaction: all-trans-decaprenyl diphosphate + 4-hydroxybenzoate = 3-decaprenyl-4-hydroxybenzoate + diphosphate.


name: regulation of syringal lignin biosynthetic process

description: Any process that modulates the frequency, rate or extent of syringal lignin biosynthetic process.


cannabinoid signaling pathway

description: A G protein-coupled receptor signaling pathway initiated by a cannabinoid binding to its receptor on the cell surface, and ending with the regulation of a downstream cellular process, e.g. transcription. Cannabinoids are a class of diverse chemical compounds that include the endocannabinoids and the phytocannabinoids.


capsorubin metabolic process

description: The chemical reactions and pathways involving capsorubin.


description: The chemical reactions and pathways resulting in the formation of (+)-epi-alpha-bisabolol.


name: positive regulation of mesenchymal cell apoptotic process involved in metanephros development

description: Any process that activates or increases the frequency, rate or extent of mesenchymal cell apoptotic process involved in metanephros development.


tetraterpenoid biosynthetic process

description: The chemical reactions and pathways resulting in the formation of tetraterpenoid compounds, terpenoids with eight isoprene units.


name: rRNA (guanine) methyltransferase activity

description: Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing methylguanine.


name: symbiont-mediated suppression of host receptor-mediated signal transduction

description: A process in which a virus interferes with, inhibits or disrupts a receptor-mediated signal transduction pathway in its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.


name: regulation of vascular associated smooth muscle cell membrane depolarization

description: Any process that modulates the establishment or extent of a membrane potential in the depolarizing direction away from the resting potential in a vascular smooth muscle cell.


violaceol II catabolic process

description: The chemical reactions and pathways resulting in the breakdown of violaceol II.


teichoic acid metabolic process

description: The chemical reactions and pathways involving teichoic acid, any polymer occurring in the cell wall, membrane or capsule of Gram-positive bacteria and containing chains of glycerol phosphate or ribitol phosphate residues.


response to interleukin-7

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-7 stimulus.


name: negative regulation of fibroblast growth factor receptor signaling pathway

description: Any process that stops, prevents, or reduces the frequency, rate or extent of fibroblast growth factor receptor signaling pathway activity.


name: ligase activity, forming carbon-sulfur bonds

description: Catalysis of the joining of two molecules via a carbon-sulfur bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.


name: regulation of raffinose metabolic process

description: Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving raffinose.


positive regulation of mismatch repair

description: Any process that activates or increases the frequency, rate or extent of mismatch repair.


protein maturation by protein folding

description: The process of assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure that results in the attainment of the full functional capacity of a protein.


protein K63-linked deubiquitination

description: A protein deubiquitination process in which a K63-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 63 of the ubiquitin monomers, is removed from a protein.


nitrilotriacetate metabolic process

description: The chemical reactions and pathways involving nitrilotriacetate, an aminotricarboxylic acid that binds bivalent metal ions in a ratio of 1:1. As an important industrial chelating agent, NTA has been widely used for various radionuclide processing and decontamination procedures, such as textile, paper and pulp processing and water treatment.


coniferin metabolic process

description: The chemical reactions and pathways involving coniferin, 4-(3-hydroxyprop-1-en-1-yl)-2-methoxyphenyl beta-D-glucopyranoside.


type III interferon production

description: The appearance of type III interferon due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Interferon lambda is the only member of the type III interferon found so far.


sensory perception of cold stimulus

description: The series of events required for an organism to receive a cold temperature stimulus, convert it to a molecular signal, and recognize and characterize the signal.


pre-miRNA 3'-end processing

description: Any process involved in forming distinct miRNA isoforms from a mature miRNA that differ at their 3'-ends.


name: 16S rRNA (guanine(966)-N(2))-methyltransferase activity

description: Catalysis of the reaction: S-adenosyl-L-methionine + guanosine(966) in 16S rRNA = N(2)-methylguanosine(966) in 16S rRNA + S-adenosyl-L-homocysteine.


phosphinothricin metabolic process

description: The chemical reactions and pathways involving phosphinothricin.


rhamnose biosynthetic process

description: The chemical reactions and pathways resulting in the formation of rhamnose, the hexose 6-deoxy-L-mannose.


regulation of basidiospore formation

description: Any process that modulates the frequency, rate or extent of basidiospore formation, a process in which a sexually produced fungal spore is formed on a basidium in the fungi Basidiomycetes.


dibasic protein processing

description: Any protein processing achieved by the cleavage of a peptide bond after two basic amino acids within a protein.


name: positive regulation of respiratory burst involved in inflammatory response

description: Any process that increases the rate, frequency or extent of a phase of elevated metabolic activity, during which oxygen consumption increases made as a defense response ; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals.


name: carbamoyl phosphate biosynthetic process

description: The chemical reactions and pathways resulting in the formation of carbamoyl phosphate, an intermediate in the urea cycle and other nitrogen compound metabolic pathways.


ribosomal skipping

description: A translation process in which a specific viral peptide prevents the ribosome from covalently linking a new inserted amino acid, and lets it continue translation, thereby cleaving the nascent protein while allowing translation to continue.


GDP-L-galactose metabolic process

description: The chemical reactions and pathways involving GDP-L-galactose, a substance composed of L-galactose in glycosidic linkage with guanosine diphosphate.


description: The chemical reactions and pathways by which a purine deoxyribonucleoside is synthesized from another purine deoxyribonucleoside.


name: creatine transmembrane transporter activity

description: Enables the transfer of creatine from one side of a membrane to the other. Creatine is a compound synthesized from the amino acids arginine, glycine, and methionine that occurs in muscle.


name: sodium:malonate symporter activity

description: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sodium(out)+ malonate(out) = sodium(in) + malonate(in).


name: modulation of molecular function in another organism

description: The process in which an organism effects a change in the function of proteins in a second organism.


name: positive regulation of meiotic cell cycle phase transition

description: Any process that activates or increases the frequency, rate or extent of meiotic cell cycle phase transition.


name: negative regulation of developmental process

description: Any process that stops, prevents or reduces the rate or extent of development, the biological process whose specific outcome is the progression of an organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).


name: negative regulation of FtsZ-dependent cytokinesis

description: Any process that stops, prevents, or reduces the frequency, rate or extent of Ftsz-dependent cytokinesis.


alpha-aminoacyl-tRNA binding

description: Binding to an alpha-aminoacyl-tRNA.


name: transport of virus in multicellular host

description: The transport of a virus between cells in a multicellular organism. The cells can be adjacent or spatially separated (e.g. in different tissues or organs).


name: negative regulation of protein kinase C signaling

description: Any process that decreases the frequency, rate, or extent of a series of reactions, mediated by the intracellular serine/threonine kinase protein kinase C, which occurs as a result of a single trigger reaction or compound.


name: delphinidin 3-O-glucoside biosynthetic process

description: The chemical reactions and pathways resulting in the formation of delphinidin 3-O-glucoside, a basic, water-soluble anthocyanin responsible for blue coloration of flowers and fruits.


arabinose metabolic process

description: The chemical reactions and pathways involving arabinose, arabino-pentose. L-Arabinose occurs both free, for example in the heartwood of many conifers, and in the combined state, as a constituent of plant hemicelluloses, bacterial polysaccharides etc. D-arabinose is a constituent of arabinonucleosides.


AGG codon-amino acid adaptor activity

description: A triplet codon-amino acid adaptor activity that recognizes an AGG codon.


description: Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a substrate.


name: antigen processing and presentation of exogenous peptide antigen

description: The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC protein complex. The peptide is typically a fragment of a larger exogenous protein which has been degraded within the cell.


dCMP biosynthetic process

description: The chemical reactions and pathways resulting in the formation of dCMP, deoxycytidine monophosphate.


ergosterol biosynthetic process

description: The chemical reactions and pathways resulting in the formation of ergosterol, (22E)-ergosta-5,7,22-trien-3-beta-ol, a sterol found in ergot, yeast and moulds.


beta-alanine catabolic process

description: The chemical reactions and pathways resulting in the breakdown of beta-alanine (3-aminopropanoic acid), an achiral amino acid and an isomer of alanine. It occurs free (e.g. in brain) and in combination (e.g. in pantothenate) but it is not a constituent of proteins.


description: Catalysis of the reaction: 3-O-[N-acetyl-beta-D-glucosaminyl-(1->3)-N-acetyl-alpha-D-galactosaminyl]-L-seryl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = 3-O-[N-acetyl-beta-D-glucosaminyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->6)]-N-acetyl-alpha-D-galactosaminyl]-L-seryl-[protein] + H+ + UDP.


bacterial-type flagellum organization

description: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a bacterial-type flagellum, a motor complex composed of an extracellular helical protein filament coupled to a rotary motor embedded in the cell envelope which functions in cell motility.


D-glutamate metabolic process

description: The chemical reactions and pathways involving D-glutamate, the D-enantiomer of the amino acid glutamate, i.e. (2R)-2-aminopentanedioic acid.


name: negative regulation of glucocorticoid receptor signaling pathway

description: Any process that stops, prevents or reduces the frequency, rate or extent of glucocorticoid receptor signaling pathway.


name: dorsal spinal cord interneuron posterior axon guidance

description: The process in which the migration of an axon growth cone of a dorsal spinal cord interneuron is directed to a specific target site in the posterior direction along the anterior-posterior body axis in response to a combination of attractive and repulsive cues. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism.


description: Catalysis of the reaction: UDP-D-glucose + vitexin = H+ + UDP + vitexin 2''-O-beta-D-glucoside.


regulation of exonuclease activity

description: Any process that modulates the frequency, rate or extent of exonuclease activity.


membrane docking

description: The initial attachment of a membrane or protein to a target membrane. Docking requires only that the proteins come close enough to interact and adhere.


name: telomere maintenance via base-excision repair

description: A telomere maintenance process that occurs by base-excision repair of telomeric DNA in response to DNA damage. Telomeric sequences are particularly susceptible to oxidative DNA damage, due to their G-rich nature.


quinate metabolic process

description: The chemical reactions and pathways involving quinate, the anion of quinic acid. The acid occurs commonly in plants, either free or as esters, and is used as a medicine.


name: positive regulation of Wnt signaling pathway, calcium modulating pathway

description: Any process that activates or increases the frequency, rate or extent of the series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors leads to an increase in intracellular calcium and activation of protein kinase C (PKC).


chemokine receptor activity

description: Combining with a chemokine, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. Chemokines are a family of small chemotactic cytokines; their name is derived from their ability to induce directed chemotaxis in nearby responsive cells. All chemokines possess a number of conserved cysteine residues involved in intramolecular disulfide bond formation. Some chemokines are considered pro-inflammatory and can be induced during an immune response to recruit cells of the immune system to a site of infection, while others are considered homeostatic and are involved in controlling the migration of cells during normal processes of tissue maintenance or development. Chemokines are found in all vertebrates, some viruses and some bacteria.


name: maintenance of transcriptional fidelity during transcription elongation by RNA polymerase II

description: Suppression of the occurrence of transcriptional errors, such as substitutions and/or insertions of nucleotides that do not correctly match the template base, during the process of transcription elongation from an RNA polymerase II promoter.


name: negative regulation of arugosin biosynthetic process

description: Any process that stops, prevents or reduces the frequency, rate or extent of arugosin biosynthetic process.


DNA rewinding

description: The process in which interchain hydrogen bonds between two single-stranded DNA (ssDNA) are reformed to regenerate double-stranded DNA (dsDNA). ssDNA is often bound and stabilized by proteins such as replication protein A (RPA) to form ssDNA bubbles. The bubbles can be rewound by ATP-dependent motors to reform base pairs between strands and thus dsDNA.


peptidyl-amino acid modification

description: The alteration of an amino acid residue in a peptide.


vein smooth muscle contraction

description: A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the vein. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The vein is a vessel carrying blood away from the capillary beds.


name: positive regulation of platelet-derived growth factor receptor signaling pathway

description: Any process that increases the frequency, rate or extent of the platelet-derived growth factor receptor signaling pathway.


name: neuronal dense core vesicle organization

description: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a neuronal dense core vesicle.


description: Catalysis of the reaction: poly-cis-polyprenyl diphosphate + isopentenyl diphosphate = diphosphate + a poly-cis-polyprenyl diphosphate longer by one C5 unit.


name: viral DNA genome packaging, 5' extended cos packaging

description: The encapsulation of the viral DNA genome within the capsid, which proceeds via cleavage of the viral DNA at specific sites to produce 5' protruding ends.


name: negative regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation

description: Any process that stops, prevents, or reduces the frequency, rate or extent of differentiation of CD4-positive, CD25-positive, alpha-beta regulatory T cells.


lipid hydroxylation

description: The covalent attachment of a hydroxyl group to one or more fatty acids in a lipid.


glutamate catabolic process to butyrate

description: The chemical reactions and pathways resulting in the breakdown of glutamate into other compounds, including butyrate.


name: nuclear receptor-mediated signaling pathway

description: The series of molecular signals initiated by a signaling molecule binding to an intracellular receptor of the nuclear receptor protein family, and ending with regulation of a downstream cellular process, e.g. transcription.


protein autosumoylation

description: The sumoylation by a protein of one or more of its own amino acid residues, or residues on an identical protein.


polyacyltrehalose biosynthetic process

description: The chemical reactions and pathways resulting in the formation of polyacyltrehalose, a pentaacylated, trehalose-based glycolipid.


prosthetic group biosynthetic process

description: The chemical reactions and pathways resulting in the formation of a prosthetic group, the non-amino acid portion of certain protein molecules. Prosthetic groups may be inorganic or organic and are usually required for the biological activity of the protein.


name: brassinosteroid mediated signaling pathway

description: The series of molecular signals mediated by the detection of brassinosteroid.


name: regulation of mesenchymal stem cell migration

description: Any process that modulates the frequency, rate or extent of mesenchymal stem cell migration.


phytoene metabolic process

description: The chemical reactions and pathways involving phytoene.


dCTP biosynthetic process

description: The chemical reactions and pathways resulting in the formation of dCTP, deoxycytidine triphosphate.


description: The chemical reactions and pathways resulting in the breakdown of (-)-exo-alpha-bergamotene.


name: negative regulation of amine catabolic process

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of amines.


stomach body smooth muscle contraction

description: A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the body of stomach. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The body of stomach is the part of the stomach that lies between the fundus above and the pyloric antrum below; its boundaries are poorly defined.


name: smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation

description: The series of molecular signals generated as a consequence of activation of the transmembrane protein Smoothened in cerebellar granule cells that contributes to the regulation of proliferation of the cells.


name: chemokine (C-C motif) ligand 20 production

description: The appearance of chemokine (C-C motif) ligand 20 (CCL20) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


monoacylglycerol catabolic process

description: The chemical reactions and pathways resulting in the breakdown of monoacylglycerol, any ester of glycerol in which any one of its hydroxyl groups has been acylated with a fatty acid, the other being non-esterified.


tRNA end turnover

description: The process in which the 3'-terminal CCA of a tRNA is removed and restored. This often happens to uncharged tRNA.


name: beta-lactam antibiotic biosynthetic process

description: The chemical reactions and pathways resulting in the formation of a beta-lactam antibiotic, any member of a class of natural or semisynthetic antibiotics whose characteristic feature is a strained, four-membered beta-lactam ring. They include the penicillins and many of the cephalosporins.


miltiradiene metabolic process

description: The chemical reactions and pathways involving miltiradiene.


name: apoptotic process involved in development

description: Any apoptotic process that is involved in anatomical structure development.


mesenchymal-endodermal cell signaling

description: Any process that mediates the transfer of information between a mesenchymal cell and an endodermal cell.


name: suppression by symbiont of host phytoalexin production

description: Any process in which a symbiont stops, prevents, or reduces the frequency, rate or extent of phytoalexin production in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.


name: cellular response to corticotropin-releasing hormone stimulus

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticotropin-releasing hormone stimulus. Corticotropin-releasing hormone is a peptide hormone involved in the stress response.


name: geranylgeranyl diphosphate biosynthetic process

description: The chemical reactions and pathways resulting in the formation of geranylgeranyl diphosphate.


name: ecdysis-triggering hormone receptor activity

description: Combining with ecdysis-triggering hormone to initiate a change in cell activity.


ACU codon-amino acid adaptor activity

description: A triplet codon-amino acid adaptor activity that recognizes an ACU codon.


brexanolone biosynthetic process

description: The chemical reactions and pathways resulting in the formation of brexanolone.


name: asymmetric protein localization involved in cell fate determination

description: Any process in which a protein is transported to, or maintained in, a specific asymmetric distribution, resulting in the formation of daughter cells of different types.


name: lysine biosynthetic process via alpha-aminoadipate and N2-acetyl-alpha-aminoadipate

description: The chemical reactions and pathways resulting in the formation of lysine via the intermediates alpha-aminoadipic acid and N2-acetyl-alpha-aminoadipate. This pathway of prokaryotic lysine biosynthesis via alpha-aminoadipate was discovered in the hyper-thermophilic Gram-negative eubacterium Thermus thermophilus. The pathway proceeds as follows: alpha-ketoglutarate is converted to homocitrate, which is metabolized to 3-carboxyhex-2-enedioate and then homoisocitrate. This is then decarboxylated to form alpha-ketoadipate, which is then converted to alpha-aminoadipate. This undergoes acetylation, to form N2-acetyl-alpha-aminoadipate, and is then phosphorylated to give N2-acetyl-alpha-aminoadipyl-delta-phosphate. This is converted to N2-acetyl-alpha-aminoadipate semialdehyde, which is then converted to N2-acetyl-L-lysine. A final deacetylation reaction produces L-lysine.


description: The phosphorylation by a protein of one or more of its own aspartate amino acid residues, or an aspartate residue on an identical protein.


geranyl diphosphate metabolic process

description: The chemical reactions and pathways involving geranyl diphosphate, the universal precursor of the monoterpenes.


anther dehiscence

description: The dehiscence of an anther to release the pollen grains contained within it.


aerobic sulfur oxidation

description: A sulfur oxidation process that proceeds via the reaction catalyzed by sulfur dioxygenase, and requires the presence of oxygen.


name: sodium:phosphate symporter activity

description: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Na+(out) + phosphate(out) = Na+(in) + phosphate(in).


protein-tetrapyrrole linkage

description: The covalent linking of a tetrapyrrole to a protein.


rRNA metabolic process

description: The chemical reactions and pathways involving rRNA, ribosomal RNA, a structural constituent of ribosomes.


nonfunctional rRNA decay

description: An rRNA catabolic process that results in the targeted detection and degradation of aberrant rRNAs contained within translationally defective ribosomes, thereby acting as a quality-control system.


cellular response to retinoic acid

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a retinoic acid stimulus.


box H/ACA sno(s)RNA processing

description: Any process involved in the conversion of a primary box H/ACA type small RNA transcript into a mature box H/ACA RNA.


name: negative regulation of receptor signaling pathway via JAK-STAT

description: Any process that stops, prevents, or reduces the frequency, rate or extent of a receptor signaling pathway via JAK-STAT.


description: The covalent attachment of a palmitoyl group to a nitrogen (N) atom in an N-terminal cysteine residue to form N-palmitoyl-L-cysteine.


name: fatty acid methyl ester metabolic process

description: The chemical reactions and pathways involving fatty acid methyl ester.


glucocorticoid catabolic process

description: The chemical reactions and pathways resulting in the breakdown of glucocorticoids, hormonal C21 corticosteroids synthesized from cholesterol.


rRNA 3'-end processing

description: Any process involved in forming the mature 3' end of an rRNA molecule.


name: protein O-linked glycosylation via hydroxyproline

description: The glycosylation of proteins via 04 atom of hydroxyproline to form O4-glycosyl-L-hydroxyproline; the most common form is arabinofuranosyl-4-proline.


name: CD4-positive, alpha-beta T cell cytokine production

description: Any process that contributes to cytokine production by a CD4-positive, alpha-beta T cell.


regulation of biological quality

description: Any process that modulates a qualitative or quantitative trait of a biological quality. A biological quality is a measurable attribute of an organism or part of an organism, such as size, mass, shape, color, etc.


3,4-dihydroxybenzoate catabolic process

description: The chemical reactions and pathways resulting in the breakdown of 3,4-dihydroxybenzoate.


name: poly(A)-dependent snoRNA 3'-end processing

description: Any process involved in forming the mature 3' end of a snoRNA molecule linked to prior polyadenylation of the 3'-end of the precursor snoRNA.


dissimilatory sulfate reduction

description: The reduction of sulfate to hydrogen sulfide, which acts as a terminal electron acceptor. Sulfate is activated to adenosine-phosphosulfate (APS) which is then reduced to sulfite, which is in turn reduced to hydrogen sulfide.


name: negative regulation of mast cell apoptotic process

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of mast cell apoptotic process.


cytoplasmic translational termination

description: The process resulting in the release of a polypeptide chain from the ribosome in the cytoplasm, usually in response to a termination codon.


cellular response to nocodazole

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nocodazole stimulus.


name: fibroblast growth factor receptor signaling pathway involved in mammary gland specification

description: The series of molecular signals initiated by binding of a fibroblast growth factor to its receptor on the surface of al cell in the epidermis resulting in the formation of the mammary line. The mammary line is a ridge of epidermal cells that will form the mammary placodes.


peripheral B cell tolerance induction

description: Tolerance induction of mature B cells in the peripheral lymphoid tissues: the blood, lymph nodes, spleen, and mucosal-associated lymphoid tissue.


myosin filament organization

description: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a filament composed of myosin molecules.


cellular response to water deprivation

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of water.


name: regulation of inositol biosynthetic process

description: Any process that modulates the frequency, rate or extent of inositol biosynthetic process.


name: envenomation resulting in blood agglutination in another organism

description: A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with specific proteins binding to cell-surface carbohydrates and causing calcium-dependent agglutination of blood cells in the bitten organism.


description: Enables the directed movement of lysophospholipids from one side of a membrane to the other. A lysophospholipid is a phospholipid that lacks one of its fatty acyl chains; it is an intermediate formed during digestion of dietary and biliary phospholipids.


interleukin-33 production

description: The appearance of interleukin-33 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


amphiregulin production

description: The appearance of amphiregulin due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Amphiregulin (AREG) is a ligand of the epidermal growth factor receptor (EGFR), a widely expressed transmembrane tyrosine kinase. AREG is synthesized as a membrane-anchored precursor protein that can engage in juxtacrine signaling on adjacent cells. Alternatively, after proteolytic processing by cell membrane proteases, mainly TACE/ADAM17, AREG is secreted and behaves as an autocrine or paracrine factor.


name: positive regulation of blood pressure in another organism

description: A process by which one organism increases the force with which blood travels through the circulatory system of another organism.


mitochondrial ncRNA surveillance

description: The set of processes involved in identifying and degrading defective or aberrant non-coding RNA transcripts (ncRNAs) within the mitochondrion.


cellular response to leucine starvation

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of leucine.


name: MAPK-activating adrenergic receptor signaling pathway

description: The series of molecular signals generated as a consequence of an adrenergic receptor binding to its physiological ligand and leading to the activation of a MAP kinase cascade.


name: positive regulation of protein kinase C signaling

description: Any process that increases the frequency, rate, or extent of a series of reactions, mediated by the intracellular serine/threonine kinase protein kinase C, which occurs as a result of a single trigger reaction or compound.


protein insertion into membrane raft

description: The process in which a protein is incorporated into a membrane raft. Membrane rafts are small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes.


receptor catabolic process

description: The chemical reactions and pathways resulting in the breakdown of a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.


name: symbiont-mediated suppression of host translation elongation

description: A process in which a symbiont inhibits or disrupts the translation elongation of host mRNA into protein, for example by directly inhibiting elongation factors. The host is defined as the larger of the organisms involved in a symbiotic interaction.


name: iron incorporation into iron-sulfur cluster via pentakis-L-cysteinyl L-histidino nickel tetrairon pentasulfide

description: The incorporation of iron into a nickel-iron-sulfur cluster via pentakis-L-cysteinyl L-histidino nickel tetrairon pentasulfide, found in carbon monoxide dehydrogenase.


gallate catabolic process

description: The chemical reactions and pathways resulting in the breakdown of gallate, the anion of gallic acid (3,4,5-trihydroxybenzoic acid).


monoacylglycerol metabolic process

description: The chemical reactions and pathways involving monoacylglycerol, any ester of glycerol in which any one of its hydroxyl groups has been acylated with a fatty acid, the other being non-esterified.


name: mammary gland branching involved in pregnancy

description: The process in which the branching structure of the mammary gland duct is generated and organized as a part of pregnancy.


amyloid-beta formation

description: The generation of amyloid-beta by cleavage of the amyloid precursor protein (APP).


arginine catabolic process

description: The chemical reactions and pathways resulting in the breakdown of arginine, 2-amino-5-(carbamimidamido)pentanoic acid.


peptidyl-histidine methylation

description: The methylation of peptidyl-L-histidine to form peptidyl-L-1'-methyl-L-histidine (otherwise known as tau-methylhistidine, tele-methylhistidine) or peptidyl-L-3'-methyl-L-histidine (otherwise known as pi-methylhistidine, pros-methylhistidine).


name: exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

description: Exonucleolytic digestion of a pre-rRNA molecule to generate the mature 3'-end of a 5.8S rRNA molecule derived from an originally tricistronic pre-rRNA transcript that contained the Small Subunit (SSU) rRNA, the 5.8S rRNA, and the Large Subunit (LSU) rRNA in that order from 5' to 3' along the primary transcript.


NAD-cap decapping

description: Cleavage of the 5'-NAD-cap of an RNA. The NAD-cap is present at the 5'-end of some RNAs in both bacetria and eukaryotes. While it promotes RNA stability in bacteria, it promotes RNA decay in eukaryotes.


name: developmental process involved in reproduction

description: A developmental process in which a progressive change in the state of some part of an organism, germline or somatic, specifically contributes to its ability to form offspring.


name: PSII associated light-harvesting complex II catabolic process

description: The chemical reactions and pathways resulting in the breakdown of one or more components of the light-harvesting complex of photosystem II.


guanine salvage

description: Any process that generates guanine, 2-amino-6-hydroxypurine, from derivatives of it without de novo synthesis.


camalexin metabolic process

description: The chemical reactions and pathways involving camalexin, an indole phytoalexin.


name: poly(ribitol phosphate) teichoic acid metabolic process

description: The chemical reactions and pathways involving poly(ribitol phosphate) teichoic acid.


name: nicotinic acid riboside metabolic process

description: The chemical reactions and pathways involving nicotinic acid riboside, the product of the formation of a glycosidic bond between ribose and nicotinic acid.


GPCR sweet taste receptor activity

description: A G protein-coupled receptor activity that is responsible for the sense of sweet taste.


name: thiamine transmembrane transporter activity

description: Enables the transfer of thiamine from one side of a membrane to the other. Thiamine is vitamin B1, a water soluble vitamin present in fresh vegetables and meats, especially liver.


name: sulfur incorporation into metallo-sulfur cluster

description: The incorporation of exogenous sulfur into a metallo-sulfur cluster.


histone H4K5 acetyltransferase activity

description: Catalysis of the reaction: acetyl-CoA + histone H4 L-lysine (position 5) = CoA + histone H4 N6-acetyl-L-lysine (position 5).


name: cellular response to non-ionic osmotic stress

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of non-ionic solutes (e.g. mannitol, sorbitol) in the environment.


name: tRNA (uracil(54)-C5)-methyltransferase activity, 5,10-methylenetetrahydrofolate-dependent

description: Catalysis of the reaction: 5,10-methylenetetrahydrofolate + tRNA containing uridine at position 54 + FADH + H+ = tetrahydrofolate + tRNA containing ribothymidine at position 54 + FAD+.


alpha-zeacarotene catabolic process

description: The chemical reactions and pathways resulting in the breakdown of alpha-zeacarotene.


D-leucine metabolic process

description: The chemical reactions and pathways involving D-leucine.


dibenzothiophene desulfurization

description: The removal of the sulfur atom from dibenzothiophene, a substance composed of two benzene rings linked by one sulfide bond and one carbon-carbon bond.


amino-acid betaine biosynthetic process

description: The chemical reactions and pathways resulting in the formation of any betaine, the N-trimethyl derivative of an amino acid.


polyterpenoid catabolic process

description: The chemical reactions and pathways resulting in the breakdown of polyterpenoid compounds, terpenoids with more than eight isoprene units.


helper T cell extravasation

description: The migration of a helper T cell from the blood vessels into the surrounding tissue. A helper T-cell is an effector T cell that provides help in the form of secreted cytokines to other immune cells.


cellular response to bile acid

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bile acid stimulus.


description: Catalysis of the reaction: nicotinate + UDP-D-glucose = N-(beta-D-glucosyl)nicotinate + UDP.


name: DNA synthesis involved in double-strand break repair via homologous recombination

description: The synthesis of DNA that contributes to the process of double-strand break repair via homologous recombination.


lipid transporter activity

description: Enables the directed movement of lipids into, out of or within a cell, or between cells.


name: adaptive immune response based on somatic recombination of immune receptors built from leucine-rich repeat domains

description: An immune response mediated by lymphocytes expressing specific receptors for antigen produced through a somatic diversification process that includes somatic recombination of variable lymphocyte receptors (VLR) incorporating leucine-rich repeat (LRR) domains, and allowing for enhanced responses upon subsequent exposures to the same antigen (immunological memory). Examples of this process are found in jawless fish, including the lampreys (Petromyzontidae) and hagfishes (Myxinidae).


name: cell cycle DNA replication maintenance of fidelity

description: Any maintenance of fidelity that is involved in cell cycle DNA replication.


description: Catalysis of the reaction: P(1),P(4)-bis(5'-nucleosyl)tetraphosphate + H2O = NTP + NMP. Acts on bis(5'-guanosyl)-, bis(5'-xanthosyl)-, bis(5'-adenosyl)- and bis(5'-uridyl)-tetraphosphate.


name: protein localization to equatorial microtubule organizing center

description: A process in which a protein is transported to, or maintained in, a location within an equatorial microtubule organizing center.


ansamycin metabolic process

description: The chemical reactions and pathways involving ansamycins, any of a group of complex macrolactam compounds characterized by a cyclic structure in which an aliphatic ansa chain forms a bridge between two non-adjacent positions of a cyclic p-system; many exhibit antibacterial, antifungal or antitumor activity.


name: tetracyclic triterpenoid metabolic process

description: The chemical reactions and pathways involving tetracyclic triterpenoid compounds, terpenoids with six isoprene units and 4 carbon rings.


name: negative regulation of osteoclast differentiation

description: Any process that stops, prevents, or reduces the frequency, rate or extent of osteoclast differentiation.


DNA conformation change

description: A cellular process that results in a change in the spatial configuration of a DNA molecule. A conformation change can bend DNA, or alter the, twist, writhe, or linking number of a DNA molecule.


name: positive regulation of programmed cell death

description: Any process that activates or increases the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes.


protein farnesyltransferase activity

description: Catalysis of the reaction: farnesyl diphosphate + protein-cysteine = S-farnesyl protein + diphosphate.


name: positive regulation of pyocyanine biosynthetic process

description: Any process that increases the frequency, rate or extent of a pyocyanine biosynthetic process.


positive regulation of neuron migration

description: Any process that activates or increases the frequency, rate or extent of neuron migration.


presynaptic signal transduction

description: Signal transduction in which the initial step occurs in a presynapse.


outer hair cell apoptotic process

description: Any apoptotic process in an outer hair cell.


name: protein localization to somatodendritic compartment

description: A process in which a protein is transported to or maintained in a location within the somatodendritic compartment.


tetrapyrrole biosynthetic process

description: The chemical reactions and pathways leading to the formation of tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next.


name: innate immune response-inhibiting signal transduction

description: The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately leading to inhibition of an innate immune response.


sucrose-phosphate synthase activity

description: Catalysis of the reaction: UDP-glucose + D-fructose 6-phosphate = UDP + sucrose 6-phosphate.


emericellin metabolic process

description: The chemical reactions and pathways involving emericellin.


CAMKK-AMPK signaling cascade

description: The series of molecular signals in which calmodulin-dependent protein kinase activity enabled by a CAMKK directly activates an AMPK. The cascade begins with calmodulin binding calcium which in turn binds CAMKK enabling its calmodulin-dependent protein kinase activity. The cascade ends with AMP-activated protein kinase activity.


dolichyldiphosphatase activity

description: Catalysis of the reaction: dolichyl diphosphate + H2O = dolichyl phosphate + phosphate.


diterpenoid catabolic process

description: The chemical reactions and pathways resulting in the breakdown of diterpenoid compounds, terpenoids with four isoprene units.


beta-adrenergic receptor activity

description: Combining with epinephrine or norepinephrine to initiate a change in cell activity via activation of a G protein, with pharmacological characteristics of beta-adrenergic receptors; the activity involves transmitting the signal to the Gs alpha subunit of a heterotrimeric G protein.


5-methylcytosine metabolic process

description: The chemical reactions and pathways involving 5-methylcytosine, a methylated base of DNA.


oxidative demethylation

description: The process of removing one or more methyl groups from a molecule, involving the oxidation (i.e. electron loss) of one or more atoms in the substrate.


TTP metabolic process

description: The chemical reactions and pathways involving TTP, ribosylthymine triphosphate.


response to light stimulus

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light stimulus, electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light.


name: negative regulation of neuronal signal transduction

description: Any process that stops, prevents or reduces the frequency, rate or extent of neuronal signal transduction.


name: positive regulation of apoptotic process involved in metanephric collecting duct development

description: Any process that activates or increases the frequency, rate or extent of apoptotic process involved in metanephric collecting duct development.


name: catechol catabolic process, meta-cleavage

description: The chemical reactions and pathways resulting in the breakdown of catechol via the meta-cleavage pathway, in which the catechol aromatic ring is broken between a hydroxylated carbon atom and an adjacent unsubstituted carbon atom.


epinephrine metabolic process

description: The chemical reactions and pathways involving epinephrine, a hormone produced by the medulla of the adrenal glands that increases heart activity, improves the power and prolongs the action of muscles, and increases the rate and depth of breathing. It is synthesized by the methylation of norepinephrine.


D-serine metabolic process

description: The chemical reactions and pathways involving D-serine, the D-enantiomer of serine, i.e. (2R)-2-amino-3-hydroxypropanoic acid.


all-trans-phytoene synthase activity

description: Catalysis of the reaction: 2 geranylgeranyl diphosphate -> all-trans-phytoene + 2 diphosphate.


U5 snRNA binding

description: Binding to a U5 small nuclear RNA (U5 snRNA).


name: nickel incorporation into iron-sulfur cluster via tris-L-cysteinyl L-cysteine persulfido bis-L-glutamato L-histidino nickel triiron disulfide trioxide

description: The incorporation of nickel into a 3Fe-2S complex by tris-L-cysteinyl L-cysteine persulfido bis-L-glutamato L-histidino nickel triiron disulfide trioxide.


name: negative regulation of activated CD4-positive, alpha-beta T cell apoptotic process

description: Any process that stops, prevents or reduces the frequency, rate or extent of activated CD4-positive, alpha-beta T cell apoptotic process.


gastrulation with mouth forming first

description: A gastrulation process in which the initial invagination becomes the mouth and the anus forms second.


peptidyl-histidine modification

description: The modification of peptidyl-histidine.


nitrotoluene metabolic process

description: The chemical reactions and pathways involving nitrotoluene, any methylbenzene molecule with NO2 group(s) attached.


fumitremorgin B biosynthetic process

description: The chemical reactions and pathways resulting in the formation of the indole alkaloid fumitremorgin B.


xanthophyll cycle

description: A cyclic series of interconversions involving three xanthophylls, violoxanthin, antheraxanthin, and zeaxanthin. The xanthophyll cycle is involved in regulating energy dissipation in light harvesting complex II.


name: ATP-dependent protein-DNA unloader activity

description: Facilitating the removal of a protein or protein complex from a DNA molecule driven by ATP hydrolysis. This can be achieved for example by introducing non-canonical DNA structures or generating torque to directly inhibit a protein-DNA binding interaction.


name: glucosinolate biosynthetic process from phenylalanine

description: The chemical reactions and pathways resulting in the formation of glucosinolates from other compounds including phenylalanine.


name: photosynthesis, light harvesting in photosystem I

description: After a photon of light is absorbed by one of the many chlorophyll molecules, in one of the light-harvesting complexes of an antenna on photosystem I, some of the absorbed energy is transferred to the pair of chlorophyll molecules in the reaction center.


regulation of epidermis development

description: Any process that modulates the frequency, rate or extent of epidermis development.


name: DNA synthesis involved in mitochondrial DNA replication

description: Any DNA biosynthetic process that is involved in mitochondrial DNA replication.


name: endoplasmic reticulum-Golgi intermediate compartment (ERGIC) derived vesicle fusion with Golgi cis cisterna membrane

description: The joining of the lipid bilayer membrane around an ERGIC-derived vesicle to the lipid bilayer membrane around the Golgi cis cisterna. Such vesicles include COPII-coated transport vesicles involved in anterograde transport.


cysteine biosynthetic process

description: The chemical reactions and pathways resulting in the formation of cysteine, 2-amino-3-mercaptopropanoic acid.


brexanolone metabolic process

description: The chemical reactions and pathways by which living organisms transform brexanolone.


nicotinamide metabolic process

description: The chemical reactions and pathways involving nicotinamide, pyridine-3-carboxamide, the amide of nicotinic acid. It is a member of the B complex of vitamins and occurs widely in living organisms.


nitrile metabolic process

description: The chemical reactions and pathways involving nitriles, an organic compound containing trivalent nitrogen attached to one carbon atom. The nitriles are named with reference to the acids produced by their decomposition; for example, hydrocyanic acid is formic nitrile, and methyl cyanide is acetic nitrile.


name: selenocysteine insertion sequence binding

description: Binding to a selenocysteine insertion sequence (SECIS), a regulatory sequence within mRNA which directs incorporation of a selenocysteine at a stop codon (UGA) during translation.


name: type I hypersensitivity mediated by basophils

description: An inflammatory response driven by antigen recognition by antibodies bound to Fc receptors basophils, occurring within minutes after exposure of a sensitized individual to the antigen, and leading to the release of a variety of inflammatory mediators such as histamines.


name: symbiont-mediated suppression of host inflammatory response

description: A process in which a symbiont inhibits or disrupts the normal execution of  inflammatory response in the host organism; the inflammatory response is the immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The host is defined as the larger of the organisms involved in a symbiotic interaction.


DNA/RNA helicase activity

description: Unwinding of a DNA/RNA duplex, i.e. a double helix in which a strand of DNA pairs with a complementary strand of RNA, driven by ATP hydrolysis.


tight junction assembly

description: A cellular process that results in the aggregation, arrangement and bonding together of a set of components to form a tight junction. A tight junction seals cells together in an epithelium in a way that prevents even small molecules from leaking from one side of the sheet to the other.


description: A lipid oxidation process proceeding through a series of three successive monooxygenations of the alpha methyl group on the C4 carbon (CH3 to CH2OH to CHO to COOH) and resulting in this overall reaction: 4,4-dimethyl-9beta,19-cyclopropylsterol + 3 NADPH + 3 H+ + 3 O2 = 4-alpha-carboxy, 4-beta-methyl-9beta,19-cyclopropylsterol + 3 NADP+ + 3 H2O.


name: negative regulation of voltage-gated potassium channel activity in another organism

description: Any process in which an organism stops, prevents or reduces the frequency, rate or extent of the activity of a voltage-gated potassium channel in another organism.


lipid ubiquitination

description: The process in which one or more ubiquitin groups are added to a lipid.


name: embryo development ending in birth or egg hatching

description: The process whose specific outcome is the progression of an embryo over time, from zygote formation until the end of the embryonic life stage. The end of the embryonic life stage is organism-specific and may be somewhat arbitrary; for mammals it is usually considered to be birth, for insects the hatching of the first instar larva from the eggshell.


anoikis

description: Apoptosis triggered by inadequate or inappropriate adherence to substrate e.g. after disruption of the interactions between normal epithelial cells and the extracellular matrix.


catalytic activity, acting on a tRNA

description: Catalytic activity that acts to modify a tRNA.


name: peroxisome proliferator activated receptor signaling pathway

description: A nuclear receptor-mediated signaling pathway initiated by a ligand binding to an intracellular peroxisome proliferator activated receptor (alpha, beta or gamma) of the nuclear receptor protein family, and ending with regulation of a downstream cellular process, e.g. transcription.


O-glycan processing, core 1

description: The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form the core 1 O-glycan structure, Gal-beta-(1->3)-GalNAc.


description: Catalysis of the reaction: UDP-N-acetylglucosamine + Skp1-protein-hydroxyproline = UDP + Skp1-protein-O-(N-acetyl-D-glucosaminyl)hydroxyproline.


regulation of body fluid levels

description: Any process that modulates the levels of body fluids.


CGA codon-amino acid adaptor activity

description: A triplet codon-amino acid adaptor activity that recognizes a CGA codon.


aerobic lactate catabolic process

description: The chemical reactions and pathways resulting in the breakdown of lactate (2-hydroxypropanoic acid) in the presence of oxygen.


name: regulation of orcinol biosynthetic process

description: Any process that modulates the frequency, rate or extent of orcinol biosynthetic process.


cellular response to calcium ion

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus.


cellular response to dinitrophenol

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dinitrophenol stimulus.


name: negative regulation of sexual sporulation resulting in formation of a cellular spore

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the formation of cellular spores derived from the products of meiosis.


amino acid:sodium symporter activity

description: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: amino acid(out) + Na+(out) = amino acid(in) + Na+(in).


asparagine biosynthetic process

description: The chemical reactions and pathways resulting in the formation of asparagine, 2-amino-3-carbamoylpropanoic acid.


DNA amplification

description: The process in which the number of copies of a gene is increased in certain cells as extra copies of DNA are made in response to certain signals of cell development or of stress from the environment.


D-xylose biosynthetic process

description: The chemical reactions and pathways resulting in the formation of D-xylose, a naturally occurring plant polysaccharide.


name: sulfur compound transmembrane transporter activity

description: Enables the transfer of a sulfur compound from one side of a membrane to the other.


acetylcholine biosynthetic process

description: The chemical reactions and pathways resulting in the formation of acetylcholine, the acetic acid ester of the organic base choline.


histone H2A acetyltransferase activity

description: Catalysis of the reaction: acetyl-CoA + histone H2A L-lysine = CoA + histone H2A N6-acetyl-L-lysine.


description: The acetylation of the N-terminal lysine of proteins to form the derivative N2-acetyl-L-lysine. The occurrence of this modification has not been confirmed.


name: D-glucuronate transmembrane transporter activity

description: Enables the transfer of D-glucuronate, the D-enantiomer of glucuronate, from one side of a membrane to the other.


regulation of mannan catabolic process

description: Any process that modulates the frequency, rate or extent of mannan catabolic process.


xanthophyll metabolic process

description: The chemical reactions and pathways involving xanthophylls, oxygen-containing carotenoids.


ADP phosphatase activity

description: Catalysis of the reaction: ADP + H2O = AMP + phosphate + H+.


regulation of olefin metabolic process

description: Any process that modulates the frequency, rate or extent of olefin metabolic process.


allantoin biosynthetic process

description: The chemical reactions and pathways resulting in the formation of allantoin, (2,5-dioxo-4-imidazolidinyl)urea.


name: serotonin-gated monoatomic cation channel activity

description: Enables the transmembrane transfer of a cation by a channel that opens when serotonin has been bound by the channel complex or one of its constituent parts.


response to external biotic stimulus

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external biotic stimulus, an external stimulus caused by, or produced by living things.


gibberellin metabolic process

description: The chemical reactions and pathways involving gibberellin. Gibberellins are a class of highly modified terpenes that function as plant growth regulators.


name: regulation of Ral protein signal transduction

description: Any process that modulates the frequency, rate or extent of Ral protein signal transduction.


name: epithelial cell apoptotic process involved in palatal shelf morphogenesis

description: An apoptotic process in a palatal shelf epithelial cell that contributes to the shaping of the palatal shelf.


glycolytic fermentation to propionate

description: Glycolytic fermentation resulting in the catabolism of glucose to propionate, yielding energy in the form of ATP; an alternative to the acrylate pathway to produce propionate.


muscle cell apoptotic process

description: A form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle a muscle cell and result in its death. A muscle cell is a mature contractile cell, commonly known as a myocyte, that forms one of three kinds of muscle.


neutral lipid metabolic process

description: The chemical reactions and pathways involving neutral lipids, lipids only soluble in solvents of very low polarity.


mechanoreceptor activity

description: Combining with a mechanical force and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity or state as part of signal transduction.


name: negative regulation of microglial cell migration

description: Any process that stops, prevents or reduces the frequency, rate or extent of microglial cell migration.


name: fatty acid transmembrane transporter activity

description: Enables the transfer of fatty acids from one side of a membrane to the other. Fatty acids are aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis.


peptidyl-serine acetylation

description: The acetylation of peptidyl-serine.


wybutosine biosynthetic process

description: The chemical reactions and pathways resulting in the formation of wybutosine, 3H-imidazo[1,2-alpha]purine-7-butanoic acid, 4,9-dihydro- alpha-[(methoxycarbonyl)amino]- 4,6-dimethyl-9-oxo- 3-beta-D-ribofuranosyl methyl ester, a modified nucleoside found in some tRNA molecules.


cellular response to cordycepin

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cordycepin stimulus.


chlorophyll biosynthetic process

description: The chemical reactions and pathways resulting in the formation of chlorophyll, any compound of magnesium complexed in a porphyrin (tetrapyrrole) ring and which functions as a photosynthetic pigment, from less complex precursors.


name: G protein-coupled amine receptor activity

description: Combining with an extracellular amine and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.


pentraxin receptor activity

description: Combining with a pentraxin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


heme C metabolic process

description: The chemical reactions and pathways involving heme c, a derivative of heme found in cytochromes c, b4, and f.


E-series resolvin biosynthetic process

description: The chemical reactions and pathways resulting in the formation of resolvin family E-series, hydroxy fatty acids derived from icosapentaenoic acid.


oxazole or thiazole metabolic process

description: The chemical reactions and pathways involving oxazole or thiazole, five-membered heterocyclic ring structures containing an oxygen and a sulfur, respectively, in the 1-position and a nitrogen in the 3-position.


lipoprotein biosynthetic process

description: The chemical reactions and pathways resulting in the formation of any conjugated, water-soluble protein in which the covalently attached nonprotein group consists of a lipid or lipids.


name: cellular response to epinephrine stimulus

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an epinephrine stimulus. Epinephrine is a catecholamine that has the formula C9H13NO3; it is secreted by the adrenal medulla to act as a hormone, and released by certain neurons to act as a neurotransmitter active in the central nervous system.


name: negative regulation of cytokinin-activated signaling pathway

description: Any process that stops, prevents, or reduces the frequency, rate or extent of cytokinin signaling.


name: capsule polysaccharide biosynthetic process

description: The chemical reactions and pathways resulting in the formation of polysaccharides that make up the capsule, a protective structure surrounding some species of bacteria and fungi.


name: energy derivation by oxidation of reduced inorganic compounds

description: The chemical reactions and pathways by which a cell derives energy from inorganic compounds; results in the oxidation of the compounds from which energy is released.


name: platelet-derived growth factor alpha-receptor activity

description: Combining with platelet-derived growth factor isoform PDGF-AA, PDGF-BB or PDGF-AB to initiate a change in cell activity.


description: Catalysis of the reaction: UDP-galactose + kaempferol = UDP + kaempferol 3-O-beta-D-galactoside.


protein alpha-1,2-demannosylation

description: The removal of one or more alpha 1,2-linked mannose residues from a mannosylated protein.


establishment of viral latency

description: A process by which a virus establishes a latent state within its host, either as an integrated provirus within the host genome or as an episome, where viral genome remains in the cytoplasm or nucleus as distinct objects.


description: Catalysis of the reaction: myo-inositol + UDP-galactose = O-alpha-D-galactosyl-(1,3)-1D-myo-inositol + UDP.


name: multicellular organismal-level water homeostasis

description: A chemical homeostatic process involved in the maintenance of a steady state level of water within extracellular body fluids, such as blood, xylem or phloem, of a multicellular organism. This is distinct from maintenance of cellular homeostasis, which occurs within a cell.


name: regulation of lymphocyte apoptotic process

description: Any process that modulates the occurrence or rate of lymphocyte death by apoptotic process.


name: ubiquinone biosynthetic process via 3,4-dihydroxy-5-polyprenylbenzoate

description: The chemical reactions and pathways resulting in the formation of ubiquinone, via the intermediates 3,4-dihydroxy-5-polyprenylbenzoate and 3-methoxy-4-hydroxy-5-polyprenylbenzoate.


name: nuclear polyadenylation-dependent snoRNA catabolic process

description: The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of a small nucleolar RNA (snoRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target snoRNA.


response to interleukin-2

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-2 stimulus.


name: transcription elongation by RNA polymerase I

description: The extension of an RNA molecule after transcription initiation and promoter clearance at an RNA polymerase I specific promoter by the addition of ribonucleotides catalyzed by RNA polymerase I.


RNA dinucleotide insertion

description: The modification of an RNA molecule by insertion of a dinucleotide.


name: regulation of plasma cell differentiation

description: Any process that modulates the frequency, rate or extent of plasma cell differentiation.


hepatocyte apoptotic process

description: Any apoptotic process in a hepatocyte, the main structural component of the liver.


chemokine-mediated signaling pathway

description: The series of molecular signals initiated by a chemokine binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.


histidyl-tRNA aminoacylation

description: The process of coupling histidine to histidyl-tRNA, catalyzed by histidyl-tRNA synthetase. The histidyl-tRNA synthetase is a class-II synthetase. The activated amino acid is transferred to the 3''-OH group of a histidine-accetping tRNA.


G protein-coupled UDP receptor activity

description: Combining with a nucleotide and transmitting the signal to a heterotrimeric G-protein complex to initiate a change in cell activity, activated by UDP.


glycine metabolic process

description: The chemical reactions and pathways involving glycine, aminoethanoic acid.


name: glucuronate transmembrane transporter activity

description: Enables the transfer of glucuronate from one side of a membrane to the other. Glucuronate is the uronic acid formally derived from glucose by oxidation of the hydroxymethylene group at C-6 to a carboxyl group.


name: clathrin coating of Golgi vesicle, trans-Golgi to endosome targeting

description: The addition of clathrin and adaptor proteins to Golgi membranes during the formation of transport vesicles that will move from the trans-Golgi to the endosome, forming a vesicle coat.


name: regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway

description: Any process that modulates the frequency, rate or extent of oxidative stress-induced neuron intrinsic apoptotic signaling pathway.


name: endoplasmic reticulum-derived vesicle fusion with endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane

description: The joining of the lipid bilayer membrane around an endoplasmic reticulum-derived vesicle to the lipid bilayer membrane of the ERGIC. Such vesicles include COPII-coated transport vesicles involved in anterograde transport.


chlorophyll catabolic process

description: The chemical reactions and pathways resulting in the breakdown of chlorophyll, any compound of magnesium complexed in a porphyrin (tetrapyrrole) ring and which functions as a photosynthetic pigment, into less complex products.


plastid membrane organization

description: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of either of the lipid bilayers surrounding a plastid.


name: regulation of DNA replication initiation involved in plasmid copy number maintenance

description: Any process that modulates the frequency, rate or extent of initiation of plasmid DNA replication that contributes to copy number maintenance.


name: chlorinated hydrocarbon catabolic process

description: The chemical reactions and pathways resulting in the breakdown of chlorinated hydrocarbons, compounds derived from hydrocarbons by replacing one or more hydrogen atoms with chlorine atoms.


UGU codon-amino acid adaptor activity

description: A triplet codon-amino acid adaptor activity that recognizes a UGU codon.


p-cumate metabolic process

description: The chemical reactions and pathways involving p-cumate.


peptide N-acetyltransferase activity

description: Catalysis of the acetylation of an amino acid residue of a peptide or protein, according to the reaction: acetyl-CoA + peptide = CoA + N-acetylpeptide.


name: negative regulation of eosinophil migration

description: Any process that stops, prevents or reduces the frequency, rate or extent of eosinophil migration.


DNA-templated transcription elongation

description: The extension of an RNA molecule after transcription initiation and promoter clearance at a DNA-dependent RNA polymerase promoter by the addition of ribonucleotides catalyzed by an RNA polymerase.


name: negative regulation of RIG-I signaling pathway

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the RIG-I signaling pathway.


name: adhesion of symbiont germination tube to host

description: The attachment of a germination tube of the symbiont to its host via adhesion molecules. The host is defined as the larger of the organisms involved in a symbiotic interaction.


name: negative regulation of myotube cell migration

description: Any process that stops, prevents, or reduces the frequency, rate or extent of myotube cell migration.


UCC codon-amino acid adaptor activity

description: A triplet codon-amino acid adaptor activity that recognizes a UCC codon.


parathion metabolic process

description: The chemical reactions and pathways involving parathion, a highly toxic organophosphate compound formerly used as a broad spectrum insecticide, acaricide, fumigant and nematocide. Degradation of parathion by sunlight or liver enzymes can result in the formation of the active compound paraoxon which interferes with the nervous system through cholinesterase inhibition.


fructan metabolic process

description: The chemical reactions and pathways involving fructan, a polysaccharide consisting of fructose residues.


name: glucocorticoid mediated signaling pathway

description: The series of molecular signals mediated by the detection of a glucocorticoid hormone.


nuclear dicing body assembly

description: The aggregation, arrangement and bonding together of a set of components to form a nuclear dicing body.


choline metabolic process

description: The chemical reactions and pathways involving choline (2-hydroxyethyltrimethylammonium), an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids and in the neurotransmitter acetylcholine.


amylopectin metabolic process

description: The chemical reactions and pathways involving an amylopectin.


name: glutamate catabolic process to ornithine

description: The chemical reactions and pathways resulting in the breakdown of glutamate into other compounds, including ornithine.


name: protein import into peroxisome matrix, docking

description: The process in which a complex formed of a peroxisome targeting sequence (PTS) receptor bound to a PTS-bearing protein docks with translocation machinery in the peroxisomal membrane.


name: regulation of cell cycle switching, mitotic to meiotic cell cycle

description: Any process that modulates the frequency, rate, or extent of mitotic to meiotic cell cycle switching, the process in which a cell switches cell cycle mode from mitotic to meiotic division.


name: regulation of ergot alkaloid biosynthetic process

description: Any process that modulates the frequency, rate or extent of ergot alkaloid biosynthetic process.


lactam biosynthetic process

description: The chemical reactions and pathways resulting in the formation of lactams, any cyclic amides of amino carboxylic acids, having a 1-azacycloalkan-2-one structure, or analogues having unsaturation or heteroatoms replacing one or more carbon atoms of the ring.


name: endoplasmic reticulum-Golgi intermediate compartment organization

description: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endoplasmic reticulum (ER)-Golgi intermediate compartment.


name: protein-N(PI)-phosphohistidine-mannitol phosphotransferase system transmembrane transporter activity

description: Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + mannitol(out) = protein histidine + mannitol phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.


rhamnolipid biosynthesis

description: The chemical reactions and pathways resulting in the formation/production of a glycolipid surfactant that acts as a bacterial biofilm dispersal.


cellular response to amphetamine

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amphetamine stimulus. Amphetamines consist of a group of compounds related to alpha-methylphenethylamine.


lipid droplet formation

description: A process that results in the assembly, arrangement of constituent parts of a lipid droplet.


protein deglutarylation

description: The removal of a glutaryl group (CO-CH2-CH2-CH2-CO) from a residue in a peptide or protein.


name: negative regulation of acetylcholine biosynthetic process

description: Any process that stops, prevents or reduces the frequency, rate or extent of acetylcholine biosynthetic process.


N-terminal peptidyl-proline methylation

description: The methylation of the N-terminal proline of proteins.


name: corticotrophin-releasing factor receptor activity

description: Combining with the corticotrophin-releasing factor family of ligands, including the urocortins, to initiate a change in cell activity.


dTMP biosynthetic process

description: The chemical reactions and pathways resulting in the formation of dTMP, deoxyribosylthymine monophosphate (2'-deoxyribosylthymine 5'-phosphate).


name: symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of RIG-I activity

description: A process in which a symbiont interferes with, inhibits or disrupts a cytoplasmic pattern recognition receptor signaling pathway by inhibiting the activity of RIG-1 (also known as DDX58). The cytoplasmic pattern recognition RIG-I recognizes viral RNA synthesized during active viral replication and signals to protect the host against viral infection, for example by inducing the expression of antiviral cytokines.


name: effector-mediated activation of programmed cell death in host

description: A symbiont process in which a molecule secreted by the symbiont activates a programmed cell death pathway in the host to suppress the host innate immune response. The host is defined as the larger of the organisms involved in a symbiotic interaction.


circadian sleep/wake cycle process

description: A behavioral process involved in the cycle from wakefulness through an orderly succession of sleep states and stages that occurs on an approximately 24 hour rhythm.


name: resolution of DNA recombination intermediates

description: The cleavage and rejoining of intermediates, such as Holliday junctions, formed during DNA recombination to produce two intact molecules in which genetic material has been exchanged.


name: transforming growth factor beta3 production

description: The appearance of transforming growth factor-beta3 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


cellular response to cyanide

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cyanide stimulus.


ventricular cardiac myofibril assembly

description: The process whose specific outcome is the progression of the ventricular cardiac myofibril over time, from its formation to the mature structure. A cardiac myofibril is a myofibril specific to cardiac muscle cells.


name: positive regulation of methanofuran metabolic process

description: Any process that activates or increases the frequency, rate or extent of methanofuran metabolic process.


cellular response to tetrahydrofolate

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tetrahydrofolate stimulus.


name: thiamine triphosphate phosphatase activity

description: Catalysis of the reaction: H2O + thiamine triphosphate = thiamine diphosphate + H+ + phosphate.


name: cysteine-type endopeptidase activity involved in apoptotic signaling pathway

description: Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile, and contributing to the apoptotic signaling pathway.


name: spatial regulation of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination

description: Any process that modulates the distribution of sites along the chromosome where meiotic DNA double-strand break formation takes place as part of reciprocal meiotic recombination.


flavonoid phytoalexin catabolic process

description: The chemical reactions and pathways resulting in the breakdown of flavonoid phytoalexins, a group of water-soluble phenolic derivatives containing a flavan skeleton, which possess antibiotic activity and are produced by plant tissues in response to infection.


4-hydroxycoumarin biosynthetic process

description: The chemical reactions and pathways resulting in the formation of 4-hydroxycoumarin.


dGMP catabolic process

description: The chemical reactions and pathways resulting in the breakdown of dGMP, deoxyguanosine monophosphate (2'-deoxyguanosine 5'-phosphate).


name: posterior lateral line neuromast deposition

description: The process in which a migrating neuromast primordium deposits clusters of undifferentiated cells (proneuromasts) along its migratory path in the developing posterior lateral line.


cyclic photosynthetic phosphorylation

description: A photosynthetic phosphorylation process in which ATP synthesis is driven by a proton gradient generated across the thylakoid membrane. Involves only photosystem I.


name: asparaginyl-tRNAAsn biosynthesis via transamidation

description: A tRNA aminoacylation process in which asparaginyl-tRNAAsn is formed by a tRNA-dependent two-step pathway. In the first step a non-discriminating aspartyl-tRNA synthetase generates the misacylated L-aspartyl-tRNAAsn species, and in the second step it is amidated to the correctly charged L-asparaginyl-tRNAAsn by the heterotrimeric aspartyl-tRNAAsn amidotransferase.


description: The series of molecular signals initiated by interleukin-20 binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.


name: tumor necrosis factor superfamily cytokine production

description: The appearance of any member of the TNF superfamily due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


methanofuran metabolic process

description: The chemical reactions and pathways involving a methanofuran.


quinate catabolic process

description: The chemical reactions and pathways resulting in the breakdown of quinate, the anion of quinic acid.


O-glycan processing, core 7

description: The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form the core 7 O-glycan structure, GalNAc-alpha-(1->6)-GalNAc.


cellular response to desiccation

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a desiccation stimulus, extreme dryness resulting from the prolonged deprivation of water.


mesonephric tubule formation

description: The developmental process pertaining to the initial formation of a mesonephric tubule from unspecified parts. A mesonephric tubule is an epithelial tube that is part of the mesonephros.


name: positive regulation of mitotic cell cycle phase transition

description: Any process that activates or increases the frequency, rate or extent of mitotic cell cycle phase transition.


cellular response to nitrosative stress

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrosative stress stimulus. Nitrosative stress is a state often resulting from exposure to high levels of nitric oxide (NO) or the highly reactive oxidant peroxynitrite, which is produced following interaction of NO with superoxide anions.


name: positive regulation of endothelial cell chemotaxis

description: Any process that activates or increases the frequency, rate or extent of endothelial cell chemotaxis.


cellular response to erythropoietin

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an erythropoietin stimulus.


peptidyl-serine ADP-deribosylation

description: The removal of ADP-ribose from ADP-ribosylserine.


name: citrate:proton symporter activity

description: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: citrate(out) + H+(out) = citrate(in) + H+(in).


xanthophyll catabolic process

description: The chemical reactions and pathways resulting in the breakdown of xanthophylls, oxygen-containing carotenoids.


interleukin-12 receptor activity

description: Combining with interleukin-12 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


name: protein localization to centriolar satellite

description: A process in which a protein is transported to, or maintained in, a location within a centriolar satellite.


regulation of type 2 immune response

description: Any process that modulates the frequency, rate, or extent of a type 2 immune response.


D-leucine biosynthetic process

description: The chemical reactions and pathways resulting in the formation of D-leucine.


name: regulation of cardiac muscle contraction by calcium ion signaling

description: Any process that modulates the frequency, rate or extent of cardiac muscle contraction by changing the calcium ion signals that trigger contraction.


name: cellular response to corticosteroid stimulus

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticosteroid hormone stimulus. A corticosteroid is a steroid hormone that is produced in the adrenal cortex. Corticosteroids are involved in a wide range of physiologic systems such as stress response, immune response and regulation of inflammation, carbohydrate metabolism, protein catabolism, blood electrolyte levels, and behavior. They include glucocorticoids and mineralocorticoids.


retinal cone cell apoptotic process

description: Any apoptotic process in a retinal cone cell, one of the two photoreceptor cell types of the vertebrate retina.


blasticidin S biosynthetic process

description: The chemical reactions and pathways resulting in the formation of blasticidin S.


regulation of amine metabolic process

description: Any process that modulates the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform amines.


name: negative regulation of acute inflammatory response to antigenic stimulus

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of an acute inflammatory response to an antigenic stimulus.


name: osmoregulated periplasmic glucan catabolic process

description: The chemical reactions and pathways resulting in the breakdown of osmoregulated periplasmic glucan.


progesterone biosynthetic process

description: The chemical reactions and pathways resulting in the formation of progesterone, a steroid hormone produced in the ovary which prepares and maintains the uterus for pregnancy. Also found in plants.


water-soluble vitamin catabolic process

description: The chemical reactions and pathways resulting in the breakdown of any of a diverse group of vitamins that are soluble in water.


ganglioside biosynthetic process

description: The chemical reactions and pathways resulting in the formation of ceramide oligosaccharides carrying in addition to other sugar residues, one or more sialic acid residues.


leukotriene B4 catabolic process

description: The chemical reactions and pathways resulting in the breakdown of leukotriene B4, a leukotriene composed of (6Z,8E,10E,14Z)-eicosatetraenoic acid having (5S)- and (12R)-hydroxy substituents.


ciliary basal body organization

description: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a ciliary basal body, a short cylindrical array of microtubules and associated proteins found at the base of a eukaryotic cilium (also called flagellum).


CDP-diacylglycerol metabolic process

description: The chemical reactions and pathways involving CDP-diacylglycerol, CDP-1,2-diacylglycerol, a substance composed of diacylglycerol in glycosidic linkage with cytidine diphosphate. It is a common intermediate in phospholipid biosynthesis.


farnesol catabolic process

description: The chemical reactions and pathways resulting in the breakdown of the sesquiterpenoid alcohol farnesol, 3,7,11-trimethyl-2,6,10,dodecatrien-1-ol.


name: allantoate transmembrane transporter activity

description: Enables the transfer of allantoate from one side of a membrane to the other. Allantoate is the end product of purine metabolism in mammals and some fish, formed form allantoin. It is widely distributed in plants as an important source of stored nitrogen.


RNA acetylation

description: The posttranscriptional addition of one or more acetyl groups to specific residues in an RNA molecule.


regulation of DNA replication

description: Any process that modulates the frequency, rate or extent of DNA replication.


name: negative regulation of microglial cell activation

description: Any process that stops, prevents or reduces the frequency, rate or extent of microglial cell activation.


aminophosphonate metabolic process

description: The chemical reactions and pathways involving aminophosphonates, phosphonic acid derivatives that contain an amino group.


name: acetyl-CoA biosynthetic process from acetate

description: The chemical reactions and pathways resulting in the formation of acetyl-CoA from acetate, either directly or via acetylphosphate.


glycine betaine catabolic process

description: The chemical reactions and pathways resulting in the breakdown of glycine betaine, N-trimethylglycine.


description: The process of coupling arginine to arginyl-tRNA in a mitochondrion, catalyzed by arginyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.


name: cytoplasmic polyadenylation-dependent rRNA catabolic process

description: The chemical reactions and pathways occurring in the cytoplasm and resulting in the breakdown of a ribosomal RNA (rRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target rRNA truncated degradation intermediate.


zeaxanthin metabolic process

description: The chemical reactions and pathways involving zeaxanthin.


ATP generation from poly-ADP-D-ribose

description: The process of generating ATP in the nucleus from poly-ADP-D-ribose. Nuclear ATP generation is required for extensive chromatin remodeling events that are energy-consuming.


name: protein C-terminal carboxyl O-methyltransferase activity

description: Catalysis of the transfer of a methyl group to the oxygen atom of a carboxyl group at the C-terminal of a protein.