name: TPST1,2 transfer SO4(2-) from PAPS to FVIII (Homo sapiens)


name: FN3K phosphorylates ketosamines (Homo sapiens)

category: biolink:MolecularActivity biolink:Occurrent biolink:OntologyClass biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent


name: FN3KRP phosphorylates PsiAm, RibAm (Homo sapiens)


name: Hypusine synthesis from eIF5A-lysine (Homo sapiens)

category: biolink:Pathway biolink:OntologyClass biolink:BiologicalProcess biolink:Occurrent biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent


name: DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A (Homo sapiens)


name: DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A (Homo sapiens)


name: DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine (Homo sapiens)


name: Hypusine synthesis from eIF5A-lysine (Mus musculus)


name: DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A (Mus musculus)


name: DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine (Mus musculus)


name: DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A (Mus musculus)


name: Hypusine synthesis from eIF5A-lysine (Rattus norvegicus)


name: DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A (Rattus norvegicus)


name: DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine (Rattus norvegicus)


name: DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A (Rattus norvegicus)


name: Hypusine synthesis from eIF5A-lysine (Canis familiaris)


name: DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A (Canis familiaris)


name: DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine (Canis familiaris)


name: DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A (Canis familiaris)


name: Hypusine synthesis from eIF5A-lysine (Bos taurus)


name: DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A (Bos taurus)


name: DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine (Bos taurus)


name: DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A (Bos taurus)


name: Hypusine synthesis from eIF5A-lysine (Sus scrofa)


name: DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine (Sus scrofa)


name: DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A (Sus scrofa)


name: DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A (Sus scrofa)


name: Hypusine synthesis from eIF5A-lysine (Danio rerio)


name: DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A (Danio rerio)


name: DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine (Danio rerio)


name: DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A (Danio rerio)


name: Hypusine synthesis from eIF5A-lysine (Xenopus tropicalis)


name: DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine (Xenopus tropicalis)


name: DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A (Xenopus tropicalis)


name: DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A (Xenopus tropicalis)


name: Hypusine synthesis from eIF5A-lysine (Gallus gallus)


name: DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A (Gallus gallus)


name: Hypusine synthesis from eIF5A-lysine (Drosophila melanogaster)


name: DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine (Drosophila melanogaster)


name: DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A (Drosophila melanogaster)


name: DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A (Drosophila melanogaster)


name: Hypusine synthesis from eIF5A-lysine (Caenorhabditis elegans)


name: DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A (Caenorhabditis elegans)


name: DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine (Caenorhabditis elegans)


name: DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A (Caenorhabditis elegans)


name: Hypusine synthesis from eIF5A-lysine (Dictyostelium discoideum)


name: DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A (Dictyostelium discoideum)


name: DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A (Dictyostelium discoideum)


name: DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine (Dictyostelium discoideum)


name: Hypusine synthesis from eIF5A-lysine (Schizosaccharomyces pombe)


name: DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A (Schizosaccharomyces pombe)


name: DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine (Schizosaccharomyces pombe)


name: DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A (Schizosaccharomyces pombe)


name: Hypusine synthesis from eIF5A-lysine (Saccharomyces cerevisiae)


name: DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A (Saccharomyces cerevisiae)


name: DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine (Saccharomyces cerevisiae)


name: DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A (Saccharomyces cerevisiae)


name: Hypusine synthesis from eIF5A-lysine (Plasmodium falciparum)


name: DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A (Plasmodium falciparum)


name: DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine (Plasmodium falciparum)


name: DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A (Plasmodium falciparum)


protein hydroxylation

category: biolink:BiologicalProcess biolink:Occurrent biolink:OntologyClass biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: The addition of a hydroxy group to a protein amino acid.


name: KDM8:Fe2+ hydroxylates an arginine residue of RPS6 (Homo sapiens)


name: ASPH:Fe2+ hydroxylates an aspartate residue of F9 (Homo sapiens)


name: JMJD7 dimer hydroxlates a lysine residue of DRG2 (Homo sapiens)


name: JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 (Homo sapiens)


name: RIOX2Fe2+ hydroxylates a histidine residue of RPL27A (Homo sapiens)


name: JMJD7 dimer hydroxlates a lysine residue of DRG1 (Homo sapiens)


peptidyl-lysine 5-dioxygenase activity

description: Catalysis of the reaction: protein L-lysine + 2-oxoglutarate + O2 = protein 5-hydroxy-L-lysine + succinate + CO2.


name: RIOX1:Fe2+ hydroxylates a histidine residue of RPL8 (Homo sapiens)


peptidyl-proline 3-dioxygenase activity

description: Catalysis of the reaction: peptidyl L-proline + 2-oxoglutarate + O2 = peptidyl trans-3-hydroxy-L-proline + succinate + CO2.


name: KDM8:Fe2+ hydroxylates an arginine residue of RCCD1 (Homo sapiens)


name: JMJD7 dimer hydroxlates a lysine residue of DRG1 (Mus musculus)


name: KDM8:Fe2+ hydroxylates an arginine residue of RCCD1 (Mus musculus)


name: JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 (Mus musculus)


name: JMJD7 dimer hydroxlates a lysine residue of DRG2 (Mus musculus)


name: JMJD6 dimer hydroxylates lysine residues of U2AF2 (Mus musculus)


name: OGFOD1:Fe2+ hydroxylates a proline residue of RPS23 (Mus musculus)


name: KDM8:Fe2+ hydroxylates an arginine residue of RPS6 (Mus musculus)


name: RIOX2Fe2+ hydroxylates a histidine residue of RPL27A (Mus musculus)


name: RIOX1:Fe2+ hydroxylates a histidine residue of RPL8 (Mus musculus)


name: OGFOD1:Fe2+ hydroxylates a proline residue of RPS23 (Rattus norvegicus)


name: KDM8:Fe2+ hydroxylates an arginine residue of RPS6 (Rattus norvegicus)


name: RIOX1:Fe2+ hydroxylates a histidine residue of RPL8 (Rattus norvegicus)


name: JMJD7 dimer hydroxlates a lysine residue of DRG1 (Rattus norvegicus)


name: KDM8:Fe2+ hydroxylates an arginine residue of RCCD1 (Rattus norvegicus)


name: JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 (Rattus norvegicus)


name: JMJD7 dimer hydroxlates a lysine residue of DRG2 (Rattus norvegicus)


name: RIOX2Fe2+ hydroxylates a histidine residue of RPL27A (Rattus norvegicus)


name: JMJD6 dimer hydroxylates lysine residues of U2AF2 (Rattus norvegicus)


name: JMJD6 dimer hydroxylates lysine residues of U2AF2 (Canis familiaris)


name: RIOX2Fe2+ hydroxylates a histidine residue of RPL27A (Canis familiaris)


name: JMJD7 dimer hydroxlates a lysine residue of DRG1 (Canis familiaris)


name: KDM8:Fe2+ hydroxylates an arginine residue of RCCD1 (Canis familiaris)


name: JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 (Canis familiaris)


name: RIOX1:Fe2+ hydroxylates a histidine residue of RPL8 (Canis familiaris)


name: JMJD7 dimer hydroxlates a lysine residue of DRG2 (Canis familiaris)


name: OGFOD1:Fe2+ hydroxylates a proline residue of RPS23 (Canis familiaris)


name: KDM8:Fe2+ hydroxylates an arginine residue of RPS6 (Canis familiaris)


name: JMJD6 dimer hydroxylates lysine residues of U2AF2 (Bos taurus)


name: JMJD7 dimer hydroxlates a lysine residue of DRG2 (Bos taurus)


name: RIOX2Fe2+ hydroxylates a histidine residue of RPL27A (Bos taurus)


name: JMJD7 dimer hydroxlates a lysine residue of DRG1 (Bos taurus)


name: KDM8:Fe2+ hydroxylates an arginine residue of RCCD1 (Bos taurus)


name: JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 (Bos taurus)


name: RIOX1:Fe2+ hydroxylates a histidine residue of RPL8 (Bos taurus)


name: OGFOD1:Fe2+ hydroxylates a proline residue of RPS23 (Bos taurus)


name: KDM8:Fe2+ hydroxylates an arginine residue of RPS6 (Bos taurus)


name: JMJD7 dimer hydroxlates a lysine residue of DRG1 (Sus scrofa)


name: KDM8:Fe2+ hydroxylates an arginine residue of RCCD1 (Sus scrofa)


name: JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 (Sus scrofa)


name: RIOX1:Fe2+ hydroxylates a histidine residue of RPL8 (Sus scrofa)


name: KDM8:Fe2+ hydroxylates an arginine residue of RPS6 (Sus scrofa)


name: RIOX2Fe2+ hydroxylates a histidine residue of RPL27A (Sus scrofa)


name: JMJD6 dimer hydroxylates lysine residues of U2AF2 (Sus scrofa)


name: OGFOD1:Fe2+ hydroxylates a proline residue of RPS23 (Sus scrofa)


name: JMJD7 dimer hydroxlates a lysine residue of DRG2 (Sus scrofa)


name: KDM8:Fe2+ hydroxylates an arginine residue of RPS6 (Danio rerio)


name: JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 (Danio rerio)


name: JMJD7 dimer hydroxlates a lysine residue of DRG1 (Danio rerio)


name: RIOX1:Fe2+ hydroxylates a histidine residue of RPL8 (Danio rerio)


name: JMJD7 dimer hydroxlates a lysine residue of DRG2 (Xenopus tropicalis)


name: JMJD6 dimer hydroxylates lysine residues of U2AF2 (Xenopus tropicalis)


name: JMJD7 dimer hydroxlates a lysine residue of DRG1 (Xenopus tropicalis)


name: OGFOD1:Fe2+ hydroxylates a proline residue of RPS23 (Xenopus tropicalis)


name: KDM8:Fe2+ hydroxylates an arginine residue of RPS6 (Xenopus tropicalis)


name: RIOX1:Fe2+ hydroxylates a histidine residue of RPL8 (Xenopus tropicalis)


name: KDM8:Fe2+ hydroxylates an arginine residue of RCCD1 (Xenopus tropicalis)


name: JMJD6 dimer hydroxylates lysine residues of U2AF2 (Gallus gallus)


name: RIOX2Fe2+ hydroxylates a histidine residue of RPL27A (Gallus gallus)


name: OGFOD1:Fe2+ hydroxylates a proline residue of RPS23 (Gallus gallus)


name: JMJD7 dimer hydroxlates a lysine residue of DRG2 (Gallus gallus)


name: JMJD7 dimer hydroxlates a lysine residue of DRG1 (Gallus gallus)


name: RIOX1:Fe2+ hydroxylates a histidine residue of RPL8 (Gallus gallus)


name: KDM8:Fe2+ hydroxylates an arginine residue of RPS6 (Gallus gallus)


name: JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 (Gallus gallus)


name: JMJD7 dimer hydroxlates a lysine residue of DRG1 (Drosophila melanogaster)


name: JMJD6 dimer hydroxylates lysine residues of U2AF2 (Drosophila melanogaster)


name: JMJD7 dimer hydroxlates a lysine residue of DRG2 (Drosophila melanogaster)


name: KDM8:Fe2+ hydroxylates an arginine residue of RPS6 (Drosophila melanogaster)


name: JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 (Drosophila melanogaster)


name: RIOX1:Fe2+ hydroxylates a histidine residue of RPL8 (Drosophila melanogaster)


name: KDM8:Fe2+ hydroxylates an arginine residue of RCCD1 (Drosophila melanogaster)


name: OGFOD1:Fe2+ hydroxylates a proline residue of RPS23 (Drosophila melanogaster)


name: JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 (Caenorhabditis elegans)


name: KDM8:Fe2+ hydroxylates an arginine residue of RCCD1 (Caenorhabditis elegans)


name: KDM8:Fe2+ hydroxylates an arginine residue of RPS6 (Caenorhabditis elegans)


name: OGFOD1:Fe2+ hydroxylates a proline residue of RPS23 (Caenorhabditis elegans)


name: JMJD6 dimer hydroxylates lysine residues of U2AF2 (Caenorhabditis elegans)


name: RIOX1:Fe2+ hydroxylates a histidine residue of RPL8 (Caenorhabditis elegans)


name: RIOX1:Fe2+ hydroxylates a histidine residue of RPL8 (Dictyostelium discoideum)


name: JMJD7 dimer hydroxlates a lysine residue of DRG2 (Dictyostelium discoideum)


name: KDM8:Fe2+ hydroxylates an arginine residue of RPS6 (Dictyostelium discoideum)


name: JMJD7 dimer hydroxlates a lysine residue of DRG1 (Dictyostelium discoideum)


name: OGFOD1:Fe2+ hydroxylates a proline residue of RPS23 (Schizosaccharomyces pombe)


name: JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 (Schizosaccharomyces pombe)


name: OGFOD1:Fe2+ hydroxylates a proline residue of RPS23 (Saccharomyces cerevisiae)


name: The activation of arylsulfatases (Homo sapiens)


name: The activation of arylsulfatases (Mus musculus)


name: The activation of arylsulfatases (Rattus norvegicus)


name: The activation of arylsulfatases (Canis familiaris)


name: The activation of arylsulfatases (Bos taurus)


name: The activation of arylsulfatases (Sus scrofa)


name: The activation of arylsulfatases (Xenopus tropicalis)


name: The activation of arylsulfatases (Gallus gallus)


name: Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus (Homo sapiens)


name: Gamma-carboxy pro-factor X transport from the endoplasmic reticulum to the Golgi apparatus (Homo sapiens)


name: Gamma-carboxy pro-factor IX transport from the endoplasmic reticulum to the Golgi apparatus (Homo sapiens)


name: Gamma-carboxy pro-BGLAP transport from the endoplasmic reticulum to the Golgi apparatus (Homo sapiens)


name: Gamma-carboxy pro-factor VII transport from the endoplasmic reticulum to the Golgi apparatus (Homo sapiens)


name: Gamma-carboxy pro-GAS6 transport from the endoplasmic reticulum to the Golgi apparatus (Homo sapiens)


name: Gamma-carboxy pro-protein Z transport from the endoplasmic reticulum to the Golgi apparatus (Homo sapiens)


name: Gamma-carboxy pro-protein S transport from the endoplasmic reticulum to the Golgi apparatus (Homo sapiens)


name: Gamma-carboxy pro-prothrombin transport from the endoplasmic reticulum to the Golgi apparatus (Homo sapiens)


name: Gamma-carboxy pro-protein C transport from the endoplasmic reticulum to the Golgi apparatus (Homo sapiens)


name: Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus (Mus musculus)


name: Gamma-carboxy pro-protein Z transport from the endoplasmic reticulum to the Golgi apparatus (Mus musculus)


name: Gamma-carboxy pro-factor X transport from the endoplasmic reticulum to the Golgi apparatus (Mus musculus)


name: Gamma-carboxy pro-protein S transport from the endoplasmic reticulum to the Golgi apparatus (Mus musculus)


name: Gamma-carboxy pro-protein C transport from the endoplasmic reticulum to the Golgi apparatus (Mus musculus)


name: Gamma-carboxy pro-factor IX transport from the endoplasmic reticulum to the Golgi apparatus (Mus musculus)


name: Gamma-carboxy pro-prothrombin transport from the endoplasmic reticulum to the Golgi apparatus (Mus musculus)


name: Gamma-carboxy pro-factor VII transport from the endoplasmic reticulum to the Golgi apparatus (Mus musculus)


name: Gamma-carboxy pro-GAS6 transport from the endoplasmic reticulum to the Golgi apparatus (Mus musculus)


name: Gamma-carboxy pro-BGLAP transport from the endoplasmic reticulum to the Golgi apparatus (Mus musculus)


name: Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus (Rattus norvegicus)


name: Gamma-carboxy pro-protein Z transport from the endoplasmic reticulum to the Golgi apparatus (Rattus norvegicus)


name: Gamma-carboxy pro-prothrombin transport from the endoplasmic reticulum to the Golgi apparatus (Rattus norvegicus)


name: Gamma-carboxy pro-factor IX transport from the endoplasmic reticulum to the Golgi apparatus (Rattus norvegicus)


name: Gamma-carboxy pro-BGLAP transport from the endoplasmic reticulum to the Golgi apparatus (Rattus norvegicus)


name: Gamma-carboxy pro-GAS6 transport from the endoplasmic reticulum to the Golgi apparatus (Rattus norvegicus)


name: Gamma-carboxy pro-factor VII transport from the endoplasmic reticulum to the Golgi apparatus (Rattus norvegicus)


name: Gamma-carboxy pro-protein C transport from the endoplasmic reticulum to the Golgi apparatus (Rattus norvegicus)


name: Gamma-carboxy pro-protein S transport from the endoplasmic reticulum to the Golgi apparatus (Rattus norvegicus)


name: Gamma-carboxy pro-factor X transport from the endoplasmic reticulum to the Golgi apparatus (Rattus norvegicus)


name: Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus (Canis familiaris)


name: Gamma-carboxy pro-GAS6 transport from the endoplasmic reticulum to the Golgi apparatus (Canis familiaris)


name: Gamma-carboxy pro-prothrombin transport from the endoplasmic reticulum to the Golgi apparatus (Canis familiaris)


name: Gamma-carboxy pro-factor VII transport from the endoplasmic reticulum to the Golgi apparatus (Canis familiaris)


name: Gamma-carboxy pro-BGLAP transport from the endoplasmic reticulum to the Golgi apparatus (Canis familiaris)


name: Gamma-carboxy pro-protein C transport from the endoplasmic reticulum to the Golgi apparatus (Canis familiaris)


name: Gamma-carboxy pro-factor IX transport from the endoplasmic reticulum to the Golgi apparatus (Canis familiaris)


name: Gamma-carboxy pro-protein S transport from the endoplasmic reticulum to the Golgi apparatus (Canis familiaris)


name: Gamma-carboxy pro-factor X transport from the endoplasmic reticulum to the Golgi apparatus (Canis familiaris)


name: Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus (Bos taurus)


name: Gamma-carboxy pro-protein S transport from the endoplasmic reticulum to the Golgi apparatus (Bos taurus)


name: Gamma-carboxy pro-factor X transport from the endoplasmic reticulum to the Golgi apparatus (Bos taurus)


name: Gamma-carboxy pro-GAS6 transport from the endoplasmic reticulum to the Golgi apparatus (Bos taurus)


name: Gamma-carboxy pro-protein C transport from the endoplasmic reticulum to the Golgi apparatus (Bos taurus)


name: Gamma-carboxy pro-factor IX transport from the endoplasmic reticulum to the Golgi apparatus (Bos taurus)


name: Gamma-carboxy pro-BGLAP transport from the endoplasmic reticulum to the Golgi apparatus (Bos taurus)


name: Gamma-carboxy pro-prothrombin transport from the endoplasmic reticulum to the Golgi apparatus (Bos taurus)


name: Gamma-carboxy pro-factor VII transport from the endoplasmic reticulum to the Golgi apparatus (Bos taurus)


name: Gamma-carboxy pro-protein Z transport from the endoplasmic reticulum to the Golgi apparatus (Bos taurus)


name: Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus (Sus scrofa)


name: Gamma-carboxy pro-factor X transport from the endoplasmic reticulum to the Golgi apparatus (Sus scrofa)


name: Gamma-carboxy pro-protein S transport from the endoplasmic reticulum to the Golgi apparatus (Sus scrofa)


name: Gamma-carboxy pro-protein C transport from the endoplasmic reticulum to the Golgi apparatus (Sus scrofa)


name: Gamma-carboxy pro-factor IX transport from the endoplasmic reticulum to the Golgi apparatus (Sus scrofa)


name: Gamma-carboxy pro-prothrombin transport from the endoplasmic reticulum to the Golgi apparatus (Sus scrofa)


name: Gamma-carboxy pro-factor VII transport from the endoplasmic reticulum to the Golgi apparatus (Sus scrofa)


name: Gamma-carboxy pro-BGLAP transport from the endoplasmic reticulum to the Golgi apparatus (Sus scrofa)


name: Gamma-carboxy pro-GAS6 transport from the endoplasmic reticulum to the Golgi apparatus (Sus scrofa)


name: Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus (Danio rerio)


name: Gamma-carboxy pro-factor IX transport from the endoplasmic reticulum to the Golgi apparatus (Danio rerio)


name: Gamma-carboxy pro-GAS6 transport from the endoplasmic reticulum to the Golgi apparatus (Danio rerio)


name: Gamma-carboxy pro-factor X transport from the endoplasmic reticulum to the Golgi apparatus (Danio rerio)


name: Gamma-carboxy pro-protein C transport from the endoplasmic reticulum to the Golgi apparatus (Danio rerio)


name: Gamma-carboxy pro-protein Z transport from the endoplasmic reticulum to the Golgi apparatus (Danio rerio)


name: Gamma-carboxy pro-protein S transport from the endoplasmic reticulum to the Golgi apparatus (Danio rerio)


name: Gamma-carboxy pro-factor VII transport from the endoplasmic reticulum to the Golgi apparatus (Danio rerio)


name: Gamma-carboxy pro-BGLAP transport from the endoplasmic reticulum to the Golgi apparatus (Danio rerio)


name: Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus (Xenopus tropicalis)


name: Gamma-carboxy pro-factor X transport from the endoplasmic reticulum to the Golgi apparatus (Xenopus tropicalis)


name: Gamma-carboxy pro-protein Z transport from the endoplasmic reticulum to the Golgi apparatus (Xenopus tropicalis)


name: Gamma-carboxy pro-prothrombin transport from the endoplasmic reticulum to the Golgi apparatus (Xenopus tropicalis)


name: Gamma-carboxy pro-factor VII transport from the endoplasmic reticulum to the Golgi apparatus (Xenopus tropicalis)


name: Gamma-carboxy pro-GAS6 transport from the endoplasmic reticulum to the Golgi apparatus (Xenopus tropicalis)


name: Gamma-carboxy pro-protein C transport from the endoplasmic reticulum to the Golgi apparatus (Xenopus tropicalis)


name: Gamma-carboxy pro-factor IX transport from the endoplasmic reticulum to the Golgi apparatus (Xenopus tropicalis)


name: Gamma-carboxy pro-BGLAP transport from the endoplasmic reticulum to the Golgi apparatus (Xenopus tropicalis)


name: Gamma-carboxy pro-protein S transport from the endoplasmic reticulum to the Golgi apparatus (Xenopus tropicalis)


name: Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus (Gallus gallus)


name: Gamma-carboxy pro-protein Z transport from the endoplasmic reticulum to the Golgi apparatus (Gallus gallus)


name: Gamma-carboxy pro-factor VII transport from the endoplasmic reticulum to the Golgi apparatus (Gallus gallus)


name: Gamma-carboxy pro-prothrombin transport from the endoplasmic reticulum to the Golgi apparatus (Gallus gallus)


name: Gamma-carboxy pro-factor X transport from the endoplasmic reticulum to the Golgi apparatus (Gallus gallus)


name: Gamma-carboxy pro-protein C transport from the endoplasmic reticulum to the Golgi apparatus (Gallus gallus)


name: Gamma-carboxy pro-GAS6 transport from the endoplasmic reticulum to the Golgi apparatus (Gallus gallus)


name: Gamma-carboxy pro-factor IX transport from the endoplasmic reticulum to the Golgi apparatus (Gallus gallus)


name: Gamma-carboxy pro-BGLAP transport from the endoplasmic reticulum to the Golgi apparatus (Gallus gallus)


name: Gamma-carboxy pro-protein S transport from the endoplasmic reticulum to the Golgi apparatus (Gallus gallus)


name: Removal of aminoterminal propeptides from gamma-carboxylated proteins (Homo sapiens)


name: Furin cleaves pro-BGLAP to BGLAP (Homo sapiens)


name: Furin cleaves pro-protein S to protein S (Homo sapiens)


name: Furin cleaves pro-factor VII to factor VII (Homo sapiens)


name: Furin cleaves pro-protein C to protein C (Homo sapiens)


name: Furin cleaves pro-factor X to factor X (Homo sapiens)


name: Furin cleaves pro-factor IX to factor IX (Homo sapiens)


name: Furin cleaves pro-protein Z to protein Z (Homo sapiens)


name: Furin cleaves pro-prothrombin to prothrombin (Homo sapiens)


name: Furin cleaves pro-GAS6 to GAS6 (Homo sapiens)


name: Removal of aminoterminal propeptides from gamma-carboxylated proteins (Mus musculus)


name: Furin cleaves pro-BGLAP to BGLAP (Mus musculus)


name: Furin cleaves pro-factor X to factor X (Mus musculus)


name: Furin cleaves pro-factor IX to factor IX (Mus musculus)


name: Furin cleaves pro-protein S to protein S (Mus musculus)


name: Furin cleaves pro-protein Z to protein Z (Mus musculus)


name: Furin cleaves pro-GAS6 to GAS6 (Mus musculus)


name: Furin cleaves pro-prothrombin to prothrombin (Mus musculus)


name: Furin cleaves pro-protein C to protein C (Mus musculus)


name: Furin cleaves pro-factor VII to factor VII (Mus musculus)


name: Removal of aminoterminal propeptides from gamma-carboxylated proteins (Rattus norvegicus)


name: Furin cleaves pro-prothrombin to prothrombin (Rattus norvegicus)


name: Furin cleaves pro-protein C to protein C (Rattus norvegicus)


name: Furin cleaves pro-GAS6 to GAS6 (Rattus norvegicus)


name: Furin cleaves pro-factor IX to factor IX (Rattus norvegicus)


name: Furin cleaves pro-protein S to protein S (Rattus norvegicus)


name: Furin cleaves pro-BGLAP to BGLAP (Rattus norvegicus)


name: Furin cleaves pro-protein Z to protein Z (Rattus norvegicus)


name: Furin cleaves pro-factor X to factor X (Rattus norvegicus)


name: Furin cleaves pro-factor VII to factor VII (Rattus norvegicus)


name: Removal of aminoterminal propeptides from gamma-carboxylated proteins (Canis familiaris)


name: Furin cleaves pro-protein S to protein S (Canis familiaris)


name: Furin cleaves pro-BGLAP to BGLAP (Canis familiaris)


name: Furin cleaves pro-factor X to factor X (Canis familiaris)


name: Furin cleaves pro-factor IX to factor IX (Canis familiaris)


name: Furin cleaves pro-prothrombin to prothrombin (Canis familiaris)


name: Furin cleaves pro-GAS6 to GAS6 (Canis familiaris)


name: Furin cleaves pro-protein C to protein C (Canis familiaris)


name: Furin cleaves pro-factor VII to factor VII (Canis familiaris)


name: Removal of aminoterminal propeptides from gamma-carboxylated proteins (Bos taurus)


name: Furin cleaves pro-protein Z to protein Z (Bos taurus)


name: Furin cleaves pro-factor IX to factor IX (Bos taurus)


name: Furin cleaves pro-factor X to factor X (Bos taurus)


name: Furin cleaves pro-GAS6 to GAS6 (Bos taurus)


name: Furin cleaves pro-protein S to protein S (Bos taurus)


name: Furin cleaves pro-BGLAP to BGLAP (Bos taurus)


name: Furin cleaves pro-protein C to protein C (Bos taurus)


name: Furin cleaves pro-factor VII to factor VII (Bos taurus)


name: Furin cleaves pro-prothrombin to prothrombin (Bos taurus)


name: Removal of aminoterminal propeptides from gamma-carboxylated proteins (Sus scrofa)


name: Furin cleaves pro-factor IX to factor IX (Sus scrofa)


name: Furin cleaves pro-factor X to factor X (Sus scrofa)


name: Furin cleaves pro-protein S to protein S (Sus scrofa)


name: Furin cleaves pro-GAS6 to GAS6 (Sus scrofa)


name: Furin cleaves pro-BGLAP to BGLAP (Sus scrofa)


name: Furin cleaves pro-protein C to protein C (Sus scrofa)


name: Furin cleaves pro-factor VII to factor VII (Sus scrofa)


name: Furin cleaves pro-prothrombin to prothrombin (Sus scrofa)


name: Removal of aminoterminal propeptides from gamma-carboxylated proteins (Danio rerio)


name: Furin cleaves pro-BGLAP to BGLAP (Danio rerio)


name: Furin cleaves pro-GAS6 to GAS6 (Danio rerio)


name: Furin cleaves pro-protein Z to protein Z (Danio rerio)


name: Furin cleaves pro-protein C to protein C (Danio rerio)


name: Furin cleaves pro-protein S to protein S (Danio rerio)


name: Furin cleaves pro-factor VII to factor VII (Danio rerio)


name: Furin cleaves pro-factor IX to factor IX (Danio rerio)


name: Furin cleaves pro-factor X to factor X (Danio rerio)


name: Removal of aminoterminal propeptides from gamma-carboxylated proteins (Xenopus tropicalis)


name: Furin cleaves pro-BGLAP to BGLAP (Xenopus tropicalis)


name: Furin cleaves pro-factor IX to factor IX (Xenopus tropicalis)


name: Furin cleaves pro-factor X to factor X (Xenopus tropicalis)


name: Furin cleaves pro-prothrombin to prothrombin (Xenopus tropicalis)


name: Furin cleaves pro-protein C to protein C (Xenopus tropicalis)


name: Furin cleaves pro-factor VII to factor VII (Xenopus tropicalis)


name: Furin cleaves pro-GAS6 to GAS6 (Xenopus tropicalis)


name: Furin cleaves pro-protein S to protein S (Xenopus tropicalis)


name: Furin cleaves pro-protein Z to protein Z (Xenopus tropicalis)


name: Removal of aminoterminal propeptides from gamma-carboxylated proteins (Gallus gallus)


name: Furin cleaves pro-factor X to factor X (Gallus gallus)


name: Furin cleaves pro-factor VII to factor VII (Gallus gallus)


name: Furin cleaves pro-protein S to protein S (Gallus gallus)


name: Furin cleaves pro-factor IX to factor IX (Gallus gallus)


name: Furin cleaves pro-prothrombin to prothrombin (Gallus gallus)


name: Furin cleaves pro-BGLAP to BGLAP (Gallus gallus)


name: Furin cleaves pro-protein Z to protein Z (Gallus gallus)


name: Furin cleaves pro-GAS6 to GAS6 (Gallus gallus)


name: Furin cleaves pro-protein C to protein C (Gallus gallus)


name: Gamma-carboxylation of protein precursors (Homo sapiens)


name: GGCX gamma-carboxylates PROZ(24-400) (pro-protein Z) (Homo sapiens)


name: GGCX gamma-carboxylates PROS1(25-676) (pro-protein S) (Homo sapiens)


name: GGCX gamma-carboxylates BGLAP(24-100) (pro-osteocalcin) (Homo sapiens)


name: GGCX gamma-carboxylates 3D-F10(32-179) (pro-factor X light chain) (Homo sapiens)


name: GGCX gamma-carboxylates 3D-F9(29-461) (pro-factor IX) (Homo sapiens)


name: GGCX gamma-carboxylates F7(21-466) (pro-factor VII) (Homo sapiens)


name: GGCX gamma-carboxylates 3D-PROC(33-197) (pro-protein C light chain) (Homo sapiens)


name: GGCX gamma-carboxylates GAS6(31-691) (pro-GAS6) (Homo sapiens)


name: GGCX gamma-carboxylates F2(25-622) (pro-prothrombin) (Homo sapiens)


name: Gamma-carboxylation of protein precursors (Mus musculus)


name: GGCX gamma-carboxylates F2(25-622) (pro-prothrombin) (Mus musculus)


name: GGCX gamma-carboxylates F7(21-466) (pro-factor VII) (Mus musculus)


name: GGCX gamma-carboxylates 3D-F9(29-461) (pro-factor IX) (Mus musculus)


name: GGCX gamma-carboxylates BGLAP(24-100) (pro-osteocalcin) (Mus musculus)


name: GGCX gamma-carboxylates PROS1(25-676) (pro-protein S) (Mus musculus)


name: GGCX gamma-carboxylates 3D-PROC(33-197) (pro-protein C light chain) (Mus musculus)


name: GGCX gamma-carboxylates 3D-F10(32-179) (pro-factor X light chain) (Mus musculus)


name: GGCX gamma-carboxylates PROZ(24-400) (pro-protein Z) (Mus musculus)


name: Gamma-carboxylation of protein precursors (Rattus norvegicus)


name: GGCX gamma-carboxylates PROZ(24-400) (pro-protein Z) (Rattus norvegicus)


name: GGCX gamma-carboxylates 3D-PROC(33-197) (pro-protein C light chain) (Rattus norvegicus)


name: GGCX gamma-carboxylates 3D-F9(29-461) (pro-factor IX) (Rattus norvegicus)


name: GGCX gamma-carboxylates BGLAP(24-100) (pro-osteocalcin) (Rattus norvegicus)


name: GGCX gamma-carboxylates PROS1(25-676) (pro-protein S) (Rattus norvegicus)


name: GGCX gamma-carboxylates F2(25-622) (pro-prothrombin) (Rattus norvegicus)


name: GGCX gamma-carboxylates F7(21-466) (pro-factor VII) (Rattus norvegicus)


name: GGCX gamma-carboxylates 3D-F10(32-179) (pro-factor X light chain) (Rattus norvegicus)


name: Gamma-carboxylation of protein precursors (Canis familiaris)


name: GGCX gamma-carboxylates F7(21-466) (pro-factor VII) (Canis familiaris)


name: GGCX gamma-carboxylates 3D-F9(29-461) (pro-factor IX) (Canis familiaris)


name: GGCX gamma-carboxylates PROS1(25-676) (pro-protein S) (Canis familiaris)


name: GGCX gamma-carboxylates 3D-PROC(33-197) (pro-protein C light chain) (Canis familiaris)


name: GGCX gamma-carboxylates F2(25-622) (pro-prothrombin) (Canis familiaris)


name: GGCX gamma-carboxylates BGLAP(24-100) (pro-osteocalcin) (Canis familiaris)


name: GGCX gamma-carboxylates 3D-F10(32-179) (pro-factor X light chain) (Canis familiaris)


name: Gamma-carboxylation of protein precursors (Bos taurus)


name: GGCX gamma-carboxylates BGLAP(24-100) (pro-osteocalcin) (Bos taurus)


name: GGCX gamma-carboxylates F2(25-622) (pro-prothrombin) (Bos taurus)


name: GGCX gamma-carboxylates PROS1(25-676) (pro-protein S) (Bos taurus)


name: GGCX gamma-carboxylates 3D-PROC(33-197) (pro-protein C light chain) (Bos taurus)


name: GGCX gamma-carboxylates F7(21-466) (pro-factor VII) (Bos taurus)


name: GGCX gamma-carboxylates 3D-F9(29-461) (pro-factor IX) (Bos taurus)


name: GGCX gamma-carboxylates 3D-F10(32-179) (pro-factor X light chain) (Bos taurus)


name: GGCX gamma-carboxylates PROZ(24-400) (pro-protein Z) (Bos taurus)


name: Gamma-carboxylation of protein precursors (Sus scrofa)


name: GGCX gamma-carboxylates F2(25-622) (pro-prothrombin) (Sus scrofa)


name: GGCX gamma-carboxylates F7(21-466) (pro-factor VII) (Sus scrofa)


name: GGCX gamma-carboxylates 3D-F9(29-461) (pro-factor IX) (Sus scrofa)


name: GGCX gamma-carboxylates PROS1(25-676) (pro-protein S) (Sus scrofa)


name: GGCX gamma-carboxylates 3D-PROC(33-197) (pro-protein C light chain) (Sus scrofa)


name: GGCX gamma-carboxylates 3D-F10(32-179) (pro-factor X light chain) (Sus scrofa)


name: GGCX gamma-carboxylates BGLAP(24-100) (pro-osteocalcin) (Sus scrofa)


name: Gamma-carboxylation of protein precursors (Xenopus tropicalis)


name: GGCX gamma-carboxylates 3D-F10(32-179) (pro-factor X light chain) (Xenopus tropicalis)


name: GGCX gamma-carboxylates PROZ(24-400) (pro-protein Z) (Xenopus tropicalis)


name: GGCX gamma-carboxylates BGLAP(24-100) (pro-osteocalcin) (Xenopus tropicalis)


name: GGCX gamma-carboxylates PROS1(25-676) (pro-protein S) (Xenopus tropicalis)


name: GGCX gamma-carboxylates 3D-PROC(33-197) (pro-protein C light chain) (Xenopus tropicalis)


name: GGCX gamma-carboxylates F7(21-466) (pro-factor VII) (Xenopus tropicalis)


name: GGCX gamma-carboxylates 3D-F9(29-461) (pro-factor IX) (Xenopus tropicalis)


name: GGCX gamma-carboxylates F2(25-622) (pro-prothrombin) (Xenopus tropicalis)


name: Synthesis of diphthamide-EEF2 (Homo sapiens)


protein methylesterase activity

description: Catalysis of the reaction: protein amino acid methyl ester + H2O = protein amino acid + methanol.


name: DPH2 transfers a 3-amino-3-carboxypropyl group from AdoMet to residue 715 of nascent EEF2 (Homo sapiens)


name: DPH6 ligates ammonium to diphthine-EEF2 (Homo sapiens)


name: DPH5 transfers four methyl groups from AdoMet to aminocarboxypropyl EEF2 (Homo sapiens)


name: Synthesis of diphthamide-EEF2 (Mus musculus)


name: DPH2 transfers a 3-amino-3-carboxypropyl group from AdoMet to residue 715 of nascent EEF2 (Mus musculus)


name: DPH6 ligates ammonium to diphthine-EEF2 (Mus musculus)


name: DPH5 transfers four methyl groups from AdoMet to aminocarboxypropyl EEF2 (Mus musculus)


name: Synthesis of diphthamide-EEF2 (Rattus norvegicus)


name: DPH6 ligates ammonium to diphthine-EEF2 (Rattus norvegicus)


name: DPH5 transfers four methyl groups from AdoMet to aminocarboxypropyl EEF2 (Rattus norvegicus)


name: Synthesis of diphthamide-EEF2 (Canis familiaris)


name: DPH5 transfers four methyl groups from AdoMet to aminocarboxypropyl EEF2 (Canis familiaris)


name: DPH6 ligates ammonium to diphthine-EEF2 (Canis familiaris)


name: DPH2 transfers a 3-amino-3-carboxypropyl group from AdoMet to residue 715 of nascent EEF2 (Canis familiaris)


name: Synthesis of diphthamide-EEF2 (Bos taurus)


name: DPH2 transfers a 3-amino-3-carboxypropyl group from AdoMet to residue 715 of nascent EEF2 (Bos taurus)


name: DPH5 transfers four methyl groups from AdoMet to aminocarboxypropyl EEF2 (Bos taurus)


name: DPH6 ligates ammonium to diphthine-EEF2 (Bos taurus)


name: Synthesis of diphthamide-EEF2 (Sus scrofa)


name: DPH6 ligates ammonium to diphthine-EEF2 (Sus scrofa)


name: DPH2 transfers a 3-amino-3-carboxypropyl group from AdoMet to residue 715 of nascent EEF2 (Sus scrofa)


name: DPH5 transfers four methyl groups from AdoMet to aminocarboxypropyl EEF2 (Sus scrofa)


name: Synthesis of diphthamide-EEF2 (Danio rerio)


name: DPH2 transfers a 3-amino-3-carboxypropyl group from AdoMet to residue 715 of nascent EEF2 (Danio rerio)


name: Synthesis of diphthamide-EEF2 (Xenopus tropicalis)


name: DPH6 ligates ammonium to diphthine-EEF2 (Xenopus tropicalis)


name: DPH2 transfers a 3-amino-3-carboxypropyl group from AdoMet to residue 715 of nascent EEF2 (Xenopus tropicalis)


name: DPH5 transfers four methyl groups from AdoMet to aminocarboxypropyl EEF2 (Xenopus tropicalis)


name: Synthesis of diphthamide-EEF2 (Gallus gallus)


name: DPH2 transfers a 3-amino-3-carboxypropyl group from AdoMet to residue 715 of nascent EEF2 (Gallus gallus)


name: DPH5 transfers four methyl groups from AdoMet to aminocarboxypropyl EEF2 (Gallus gallus)


name: DPH6 ligates ammonium to diphthine-EEF2 (Gallus gallus)


name: Synthesis of diphthamide-EEF2 (Drosophila melanogaster)


name: DPH2 transfers a 3-amino-3-carboxypropyl group from AdoMet to residue 715 of nascent EEF2 (Drosophila melanogaster)


name: DPH6 ligates ammonium to diphthine-EEF2 (Drosophila melanogaster)


name: DPH5 transfers four methyl groups from AdoMet to aminocarboxypropyl EEF2 (Drosophila melanogaster)


name: Synthesis of diphthamide-EEF2 (Caenorhabditis elegans)


name: DPH2 transfers a 3-amino-3-carboxypropyl group from AdoMet to residue 715 of nascent EEF2 (Caenorhabditis elegans)


name: DPH5 transfers four methyl groups from AdoMet to aminocarboxypropyl EEF2 (Caenorhabditis elegans)


name: DPH6 ligates ammonium to diphthine-EEF2 (Caenorhabditis elegans)


name: Synthesis of diphthamide-EEF2 (Dictyostelium discoideum)


name: DPH2 transfers a 3-amino-3-carboxypropyl group from AdoMet to residue 715 of nascent EEF2 (Dictyostelium discoideum)


name: DPH5 transfers four methyl groups from AdoMet to aminocarboxypropyl EEF2 (Dictyostelium discoideum)


name: DPH6 ligates ammonium to diphthine-EEF2 (Dictyostelium discoideum)


name: Synthesis of diphthamide-EEF2 (Schizosaccharomyces pombe)


name: DPH6 ligates ammonium to diphthine-EEF2 (Schizosaccharomyces pombe)


name: DPH2 transfers a 3-amino-3-carboxypropyl group from AdoMet to residue 715 of nascent EEF2 (Schizosaccharomyces pombe)


name: DPH5 transfers four methyl groups from AdoMet to aminocarboxypropyl EEF2 (Schizosaccharomyces pombe)


name: Synthesis of diphthamide-EEF2 (Saccharomyces cerevisiae)


name: DPH5 transfers four methyl groups from AdoMet to aminocarboxypropyl EEF2 (Saccharomyces cerevisiae)


name: DPH6 ligates ammonium to diphthine-EEF2 (Saccharomyces cerevisiae)


name: DPH2 transfers a 3-amino-3-carboxypropyl group from AdoMet to residue 715 of nascent EEF2 (Saccharomyces cerevisiae)


name: Synthesis of diphthamide-EEF2 (Plasmodium falciparum)


name: DPH5 transfers four methyl groups from AdoMet to aminocarboxypropyl EEF2 (Plasmodium falciparum)


name: DPH2 transfers a 3-amino-3-carboxypropyl group from AdoMet to residue 715 of nascent EEF2 (Plasmodium falciparum)


name: VKORC1 inhibitors binds VKORC1 dimer (Homo sapiens)


name: VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) (Homo sapiens)


prenyltransferase activity

description: Catalysis of the transfer of a prenyl group from one compound (donor) to another (acceptor).


name: VKORC1L1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) (Homo sapiens)


name: VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) (Mus musculus)


name: VKORC1 inhibitors binds VKORC1 dimer (Mus musculus)


name: UBIA1D prenylates menadione to form MK4 (vitamin K hydroquinone) (Mus musculus)


name: VKORC1L1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) (Mus musculus)


name: Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation (Mus musculus)


name: FN3KRP phosphorylates PsiAm, RibAm (Mus musculus)


name: ICMT:Zn2+ transfers CH3 from AdoMet to isoprenylated proteins (Mus musculus)


name: FN3K phosphorylates ketosamines (Mus musculus)


name: TPST1,2 transfer SO4(2-) from PAPS to FVIII (Mus musculus)


name: Metabolism of vitamin K (Rattus norvegicus)


name: UBIA1D prenylates menadione to form MK4 (vitamin K hydroquinone) (Rattus norvegicus)


name: VKORC1 inhibitors binds VKORC1 dimer (Rattus norvegicus)


name: VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) (Rattus norvegicus)


name: VKORC1L1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) (Rattus norvegicus)


name: Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation (Rattus norvegicus)


name: TPST1,2 transfer SO4(2-) from PAPS to FVIII (Rattus norvegicus)


name: ICMT:Zn2+ transfers CH3 from AdoMet to isoprenylated proteins (Rattus norvegicus)


name: FN3K phosphorylates ketosamines (Rattus norvegicus)


name: FN3KRP phosphorylates PsiAm, RibAm (Rattus norvegicus)


name: Metabolism of vitamin K (Canis familiaris)


name: VKORC1 inhibitors binds VKORC1 dimer (Canis familiaris)


name: VKORC1L1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) (Canis familiaris)


name: VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) (Canis familiaris)


name: UBIA1D prenylates menadione to form MK4 (vitamin K hydroquinone) (Canis familiaris)


name: Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation (Canis familiaris)


name: FN3KRP phosphorylates PsiAm, RibAm (Canis familiaris)


name: FN3K phosphorylates ketosamines (Canis familiaris)


name: VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) (Bos taurus)


name: UBIA1D prenylates menadione to form MK4 (vitamin K hydroquinone) (Bos taurus)


name: VKORC1L1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) (Bos taurus)


name: VKORC1 inhibitors binds VKORC1 dimer (Bos taurus)


name: Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation (Bos taurus)


name: ICMT:Zn2+ transfers CH3 from AdoMet to isoprenylated proteins (Bos taurus)


name: FN3KRP phosphorylates PsiAm, RibAm (Bos taurus)


name: TPST1,2 transfer SO4(2-) from PAPS to FVIII (Bos taurus)


name: VKORC1 inhibitors binds VKORC1 dimer (Sus scrofa)


name: UBIA1D prenylates menadione to form MK4 (vitamin K hydroquinone) (Sus scrofa)


name: VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) (Sus scrofa)


name: VKORC1L1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) (Sus scrofa)


name: Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation (Sus scrofa)


name: FN3KRP phosphorylates PsiAm, RibAm (Sus scrofa)


name: FN3K phosphorylates ketosamines (Sus scrofa)


name: VKORC1L1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) (Danio rerio)


name: UBIA1D prenylates menadione to form MK4 (vitamin K hydroquinone) (Danio rerio)


name: Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation (Danio rerio)


name: FN3K phosphorylates ketosamines (Danio rerio)


name: FN3KRP phosphorylates PsiAm, RibAm (Danio rerio)


name: ICMT:Zn2+ transfers CH3 from AdoMet to isoprenylated proteins (Danio rerio)


name: Metabolism of vitamin K (Xenopus tropicalis)


name: UBIA1D prenylates menadione to form MK4 (vitamin K hydroquinone) (Xenopus tropicalis)


name: VKORC1 inhibitors binds VKORC1 dimer (Xenopus tropicalis)


name: VKORC1L1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) (Xenopus tropicalis)


name: VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) (Xenopus tropicalis)


name: Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation (Xenopus tropicalis)


name: FN3K phosphorylates ketosamines (Xenopus tropicalis)


name: FN3KRP phosphorylates PsiAm, RibAm (Xenopus tropicalis)


name: ICMT:Zn2+ transfers CH3 from AdoMet to isoprenylated proteins (Xenopus tropicalis)


name: Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation (Gallus gallus)


name: TPST1,2 transfer SO4(2-) from PAPS to FVIII (Gallus gallus)


name: FN3KRP phosphorylates PsiAm, RibAm (Gallus gallus)


name: ICMT:Zn2+ transfers CH3 from AdoMet to isoprenylated proteins (Gallus gallus)


name: FN3K phosphorylates ketosamines (Gallus gallus)


name: Metabolism of vitamin K (Drosophila melanogaster)


name: VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) (Drosophila melanogaster)


name: UBIA1D prenylates menadione to form MK4 (vitamin K hydroquinone) (Drosophila melanogaster)


name: VKORC1 inhibitors binds VKORC1 dimer (Drosophila melanogaster)


name: Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation (Drosophila melanogaster)


name: ICMT:Zn2+ transfers CH3 from AdoMet to isoprenylated proteins (Drosophila melanogaster)


name: Metabolism of vitamin K (Dictyostelium discoideum)


name: UBIA1D prenylates menadione to form MK4 (vitamin K hydroquinone) (Dictyostelium discoideum)


name: Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation (Dictyostelium discoideum)


name: ICMT:Zn2+ transfers CH3 from AdoMet to isoprenylated proteins (Dictyostelium discoideum)


name: Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation (Caenorhabditis elegans)


name: FN3K phosphorylates ketosamines (Caenorhabditis elegans)


name: FN3KRP phosphorylates PsiAm, RibAm (Caenorhabditis elegans)


name: ICMT:Zn2+ transfers CH3 from AdoMet to isoprenylated proteins (Caenorhabditis elegans)


name: Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation (Schizosaccharomyces pombe)


name: ICMT:Zn2+ transfers CH3 from AdoMet to isoprenylated proteins (Schizosaccharomyces pombe)


name: Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation (Saccharomyces cerevisiae)


name: ICMT:Zn2+ transfers CH3 from AdoMet to isoprenylated proteins (Saccharomyces cerevisiae)


name: Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation (Plasmodium falciparum)


name: ICMT:Zn2+ transfers CH3 from AdoMet to isoprenylated proteins (Plasmodium falciparum)


name: Defective F8 cleavage by thrombin (Homo sapiens)


name: F8 variant is not cleaved by thrombin (Homo sapiens)


name: Defective F8 binding to the cell membrane (Homo sapiens)


name: F8 variant does not bind the cell membrane (Homo sapiens)


name: Defective F8 binding to von Willebrand factor (Homo sapiens)


name: F8 variant does not bind von Willebrand factor (Homo sapiens)


name: F8 variant is not secreted (Homo sapiens)


name: Defective cofactor function of FVIIIa variant (Homo sapiens)


name: FVIIIa variant:FIXa does not convert FX to the active FXa (Homo sapiens)


name: F9 variant is not secreted (Homo sapiens)


name: Defective F9 variant does not activate FX (Homo sapiens)


name: FIXa variant:FVIIIa does not convert FX to the active FXa (Homo sapiens)


name: FIX(29-461) variant is not activated (factor XIa catalyst) (Homo sapiens)


name: Defective gamma-carboxylation of F9 (Homo sapiens)


name: GGCX does not gamma-carboxylate 3D-F9(29-461) (pro-factor IX) (Homo sapiens)


name: Defective SERPING1 causes hereditary angioedema (Homo sapiens)


name: SERPING1 variant is not secreted (Homo sapiens)


name: SERPING1 variant does not bind kallikrein (Homo sapiens)


name: SERPING1 variant does not bind factor XIIa (Homo sapiens)


name: Defective factor XII causes hereditary angioedema (Homo sapiens)


name: Cleavage of FXII variant by KLKB1 (Homo sapiens)


name: Cleavage of factor XII variant by activated thrombin (Homo sapiens)


name: Defective factor IX causes thrombophilia (Homo sapiens)


name: Hyperactivation of factor X by FVIIIa:FIXa R384L (Homo sapiens)


name: InlB-mediated entry of Listeria monocytogenes into host cell (Homo sapiens)


name: CBL recruits CIN85:endophilin complex to InlB-bound MET (Homo sapiens)


name: CBL binds InlB-activated MET (Homo sapiens)


name: CBL monoubiquitinates InlB-bound MET (Homo sapiens)


name: InlB promotes MET dimerization (Homo sapiens)


name: EPS15 and HGS bind CBL-monoubiquitinated MET engaged with Listeria InlB (Homo sapiens)


name: InlB-activated MET phosphorylates CBL (Homo sapiens)


name: InlB:MET dimer trans-autophophorylates (Homo sapiens)


name: InlA-mediated entry of Listeria monocytogenes into host cells (Homo sapiens)


name: CBLL1 ubiqutinates the InlA-bound CDH1 complex (Homo sapiens)


name: SRC autophosphorylation is positively regulated by InlA-bound CDH1 (Homo sapiens)


name: CBLL1 binds SRC-phosphorylated CDH1 complex (Homo sapiens)


name: SRC phosphorylates InlA-bound CDH1 and CTNNB1 (Homo sapiens)


name: Intestinal infectious diseases (Homo sapiens)


name: Uptake and function of anthrax toxins (Homo sapiens)


name: ANTXR2-bound pagA(197-794) forms oligomers (Homo sapiens)


name: Furin cleaves ANTXR1-bound pagA to yield pagA(197-794) (Homo sapiens)


name: Anthrax cya catalyzes the conversion of ATP to cAMP (Homo sapiens)


name: Anthrax lef cleaves target cell MAP2K7 (MEK7) (Homo sapiens)


name: Anthrax lef cleaves target cell MAP2K2 (MEK2) (Homo sapiens)


name: ANTXR1-bound pagA(197-794) forms oligomers (Homo sapiens)


name: Anthrax lef cleaves target cell MAP2K4 (MEK4) (Homo sapiens)


name: pagA(197-794):ANTRX2 oligomer transports cya and lef (target cell endosome to cytosol) (Homo sapiens)


name: Endocytosis of cya:lef:(pagA(197-794):ANTXR1 oligomer) (plasma membrane to endosome membrane) (Homo sapiens)


name: Furin cleaves ANTXR2-bound pagA to yield pagA(197-794) (Homo sapiens)


name: pagA(197-794):ANTRX1 oligomer transports cya and lef (target cell endosome to cytosol) (Homo sapiens)


name: FURIN binds furin inhibitors (Homo sapiens)

definition: Inhibition


name: Anthrax lef cleaves target cell MAP2K3 (MEK3) (Homo sapiens)


name: cya and lef bind to pagA(197-794):ANTXR1 oligomer (Homo sapiens)


name: Anthrax lef cleaves target cell MAP2K1 (MEK1) (Homo sapiens)


name: cya and lef bind to pagA(197-794):ANTXR2 oligomer (Homo sapiens)


name: Anthrax lef cleaves target cell MAP2K6 (MEK6) (Homo sapiens)


name: Endocytosis of cya:lef:(pagA(197-794):ANTXR2 oligomer) (plasma membrane to endosome membrane) (Homo sapiens)


name: Toxicity of botulinum toxin type E (botE) (Homo sapiens)


name: botE HC transports botE LC from target cell synaptic vesicle membrane into cytosol (Homo sapiens)


name: botE HC:LC binds SV2A or B and GT1b on the target cell surface (Homo sapiens)


name: botE:SV2:GT1b internalized from target cell plasma membrane to synaptic vesicle membrane (Homo sapiens)


name: botE LC cleaves target cell SNAP25 (Homo sapiens)


name: Transcytosis and dissociation of botE:NTNHA (Homo sapiens)


name: Toxicity of botulinum toxin type F (botF) (Homo sapiens)


name: botF LC cleaves target cell VAMP2 (Homo sapiens)


name: botF:SV2:GT1b internalized from target cell plasma membrane to synaptic vesicle membrane (Homo sapiens)


name: botF LC cleaves target cell VAMP1 (Homo sapiens)


name: botF HC transports botF LC from target cell synaptic vesicle membrane into cytosol (Homo sapiens)


name: botF HC:LC binds SV2A or B or C and GT1b on the target cell surface (Homo sapiens)


name: Toxicity of tetanus toxin (tetX) (Homo sapiens)


name: tetX LC cleaves target cell VAMP2 (Homo sapiens)


name: tetX HC transports tetX LC from target cell endosome membrane into cytosol (Homo sapiens)


name: tetX HC:LC binds target cell-surface gangliosides (Homo sapiens)


name: Retrograde transport of internalized tetX HC:LC:gangliosides (Homo sapiens)


name: Clathrin-mediated endocytosis of tetX HC:LC:gangliosides (Homo sapiens)


name: Toxicity of botulinum toxin type A (botA) (Homo sapiens)


name: botA HC:LC binds SV2A, B, or C and GT1b on the target cell surface (Homo sapiens)


name: botA HC transports botA LC from target cell synaptic vesicle membrane into cytosol (Homo sapiens)


name: botA:SV2:GT1b internalized from target cell plasma membrane to synaptic vesicle membrane (Homo sapiens)


name: botA LC cleaves target cell SNAP25 (Homo sapiens)


name: Transcytosis and dissociation of botA:NTNHA:HA (Homo sapiens)


name: Toxicity of botulinum toxin type C (botC) (Homo sapiens)


name: botC LC cleaves target cell STX1 (Homo sapiens)


name: botC:GT1b internalized from target cell plasma membrane to synaptic vesicle membrane (Homo sapiens)


name: botC LC cleaves target cell SNAP25 (Homo sapiens)


name: botC HC:LC binds GT1b on the target cell surface (Homo sapiens)


name: botC HC transports botC LC from target cell synaptic vesicle membrane to cytosol (Homo sapiens)


name: Toxicity of botulinum toxin type D (botD) (Homo sapiens)


name: botD HC:LC binds SV2A or B or C and GD2 on the target cell surface (Homo sapiens)


name: botD LC cleaves target cell VAMP2 (Homo sapiens)


name: botD LC cleaves target cell VAMP1 (Homo sapiens)


name: botD HC transports botD LC from target cell synaptic vesicle membrane into cytosol (Homo sapiens)


name: botD:SV2:GD2 internalized from target cell plasma membrane to synaptic vesicle membrane (Homo sapiens)


name: Toxicity of botulinum toxin type G (botG) (Homo sapiens)


name: botG HC transports botG LC from target cell synaptic vesicle membrane into cytosol (Homo sapiens)


name: botG HC:LC binds SYT1 and GT1b on the target cell surface (Homo sapiens)


name: botG:SYT1:GT1b internalized from target cell plasma membrane to synaptic vesicle membrane (Homo sapiens)


name: botG LC cleaves target cell VAMP2 (Homo sapiens)


name: botG LC cleaves target cell VAMP1 (Homo sapiens)


name: Toxicity of botulinum toxin type B (botB) (Homo sapiens)


name: botB LC cleaves target cell VAMP2 (Homo sapiens)


name: botB HC:LC binds SYT1 or 2 and GT1b on the target cell surface (Homo sapiens)


name: botB HC transports botB LC from target cell synaptic vesicle membrane into cytosol (Homo sapiens)


name: Transcytosis and dissociation of botB:NTNHA:HA (Homo sapiens)


name: botB:SYT:GT1b internalized from target cell plasma membrane to synaptic vesicle membrane (Homo sapiens)


name: Uptake and function of diphtheria toxin (Homo sapiens)


name: DT:HBEGF:CD9 is transported from clathrin-coated vesicle to endosome (Homo sapiens)


name: Clathrin-mediated endocytosis of DT:HBEGF:CD9 (Homo sapiens)


name: DT fragment B transports DT fragment A from target cell endosome membrane (Homo sapiens)


name: DT fragment A ADP-ribosylates target cell EEF (Homo sapiens)


name: DT A:B binds HBEGF and CD9 on the target cell surface (Homo sapiens)


name: Blockage of phagosome acidification (Homo sapiens)


name: Inhibition of nitric oxide production (Homo sapiens)


name: NOS2 gene produces NOS2 protein (Homo sapiens)


name: PPE2:KPNA1:KPNB1 translocates to the nucleus (Homo sapiens)


name: PPE2:KPNA1:KPNB1 dissociates, releasing PPE2 into the nucleus (Homo sapiens)


name: Prevention of phagosomal-lysosomal fusion (Homo sapiens)


name: ndkA dephosphorylates RAB5A:GTP,RAB7A:GTP (Homo sapiens)


name: lprG dissociates from LAM,LM (Homo sapiens)


name: SapM dephosphorylates PI3P (Homo sapiens)


name: LAM translocates from the cell wall to the plasma membrane (Homo sapiens)


name: Rv1410c transports lprG:LM,LAM from cytosol to the cell wall (Homo sapiens)


name: SecA2 transports SapM from cytoplasm to cytosol (Homo sapiens)


name: PtpA:Ub dephosphorylates p-Y133-VPS33B (Homo sapiens)


name: esxG:esxH binds HGS (Homo sapiens)


name: Manipulation of host energy metabolism (Homo sapiens)


name: PtpA dephosphorylates GSK3A (Homo sapiens)


name: Rv3364c binds cathepsin G (Homo sapiens)


name: Inhibition of membrane repair (Homo sapiens)


name: esxG:esxH translocates from MTb cytosol to host phagosomal lumen (Homo sapiens)


name: Phagocyte cell death caused by cytosolic Mtb (Homo sapiens)


name: Antimicrobial action and antimicrobial resistance in Mtb (Homo sapiens)


name: Defective rpoB in Mtb RNAP transcribes RNA polyanion (Homo sapiens)


name: RNAP transcribes Mtb RNA polyanion (Homo sapiens)


name: Rifampicin binds Mtb RNAP (Homo sapiens)


name: Modulation by Mtb of host immune system (Homo sapiens)


name: esxA translocates from Mtb cytosol to the host's ER (Homo sapiens)


name: Potential therapeutics for SARS (Homo sapiens)


name: SIGMAR1 binds fluvoxamine (Homo sapiens)

definition: Antagonist


name: ACE2 is glycosylated to glycosylated-ACE2 (Homo sapiens)


name: SIGMAR1 binds dextromethorphan (Homo sapiens)

definition: Agonist


name: COMT binds COMT Inhibitors (Homo sapiens)


CRBN binds IMiDs (Homo sapiens)

definition: Binding


name: Early Phase of HIV Life Cycle (Homo sapiens)


name: Removal of plus-strand flap and gap closure complete synthesis of linear duplex viral DNA (Homo sapiens)


name: Annealing of 3'-end of unwound transfer RNA primer with genomic RNA (Homo sapiens)


name: Formation of RTC (Reverse Transcription Complex) (Homo sapiens)


name: Binding and entry of HIV virion (Homo sapiens)


name: Binding of gp120 of ENV oligomer to the host CD4 (Homo sapiens)


name: Fusion of viral membrane with host cell membrane (Homo sapiens)


name: N and C terminal heptad repeat helices of gp41 form six-helix bundle (Homo sapiens)


name: Conformational change in gp120 of Env oligomer (Homo sapiens)


name: Insertion of gp41 fusion peptide into the target membrane (Homo sapiens)


name: CD4:gp120  binds to chemokine co-receptor CCR5/CXCR4 (Homo sapiens)


name: Conformational changes in gp120 exposes gp41 (Homo sapiens)


name: Fusogenic activation of gp41 (Homo sapiens)


name: Import of PIC to the Host Nucleus (Homo sapiens)


name: Formation of Pre-Integration Complex (PIC) (Homo sapiens)


name: Terminal (3' end) cleavage of viral DNA (Homo sapiens)


name: Formation of RTC with integration competent viral DNA:BANF1:HMGA1:PSIP1 (Homo sapiens)


name: Integrase binds viral DNA ends (Homo sapiens)


name: Autointegration results in viral DNA circles (Homo sapiens)


name: Suicidal integration leading to inverted circle formation (Homo sapiens)


name: Suicidal integration leading to smaller circles of viral DNA (Homo sapiens)


name: Association of  XRCC4:DNA ligase IV complex with viral DNA ends (Homo sapiens)


name: 2-LTR formation due to circularization of viral DNA (Homo sapiens)


name: Association of Ku heterodimer with viral DNA ends (Homo sapiens)


name: Integration of viral DNA into host genomic DNA (Homo sapiens)


integrase activity

description: Catalysis of the integration of one DNA segment into another.


name: Gap repair completes provirus integration (Homo sapiens)


name: Minus-strand DNA synthesis (Homo sapiens)


name: Minus strand DNA synthesis resumes (Homo sapiens)


name: Synthesis of minus strand strong stop DNA (-sssDNA) (Homo sapiens)


name: RNase H-mediated degradation of the template strand (Homo sapiens)


name: RNase H-mediated degradation of the RNA strand of the -sssDNA:RNA duplex (Homo sapiens)


name: First strand transfer mediated by Repeated (R) sequence (Homo sapiens)


name: RNase H-mediated cleavage of the RNA strand of the -sssDNA:RNA duplex (Homo sapiens)


name: RNase H-mediated cleavage of the template strand (Homo sapiens)


name: Plus-strand DNA synthesis (Homo sapiens)


name: Synthesis of full-length duplex viral DNA with a discontinuous plus strand (Homo sapiens)


name: RNase H-mediated digestion of tRNA, 3'PPT and cPPT RNA primers (Homo sapiens)


name: 3' PPT-primed initiation of plus-strand DNA synthesis  (Homo sapiens)


name: Second strand transfer by annealing complementary PBS sequences (Homo sapiens)


name: Uncoating of the HIV Virion (Homo sapiens)


name: Disintegration of matrix layer (Homo sapiens)


name: Disassembly of viral capsid (Homo sapiens)


name: Late Phase of HIV Life Cycle (Homo sapiens)


name: Assembly Of The HIV Virion (Homo sapiens)


name: Packaging of HIV virion on the host cell plasma membrane (Homo sapiens)


name: Synthesis and processing of ENV and VPU (Homo sapiens)


name: Glycosylation of ENV polyprotein (Homo sapiens)


name: Transport of trimeric gp41:gp120 to plasma membrane (Homo sapiens)


name: Synthesis of ENV polyprotein (Homo sapiens)


name: Cleavage of the viral Env gp160 precursor polyprotein (Homo sapiens)


name: Transport of trimeric ENV precursor to Golgi apparatus (Homo sapiens)


name: Folding and Oligomerization of ENV glycoprotein (Homo sapiens)


name: Splicing of HIV RNA transcript (Homo sapiens)


name: Transport of VPU to Plasma Membrane (Homo sapiens)


name: Transport of VPU to Golgi apparatus (Homo sapiens)


name: Synthesis And Processing Of GAG, GAGPOL Polyproteins (Homo sapiens)


name: Synthesis of GAG polyprotein (Homo sapiens)


name: Membrane binding and targetting of GAG proteins (Homo sapiens)


name: Monoubiquitinated N-myristoyl GAG polyprotein is targeted to the late endosomal vesicle membrane by the ESCRT-I complex (Homo sapiens)


name: Transport of GAG to the Plasma Membrane (Homo sapiens)


name: N-myristoylation of GAG polyprotein by NMT2 (Homo sapiens)


name: Monoubiquitination of N-myristoyl GAG polyprotein (Homo sapiens)


name: Budding and maturation of HIV virion (Homo sapiens)


name: Protease binds protease inhibitors (Homo sapiens)


name: Recruitment Of HIV Virion Budding Machinery (Homo sapiens)


name: abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ (Homo sapiens)


name: carbovir monophosphate + ATP => carbovir diphosphate + ADP (Homo sapiens)


name: abacavir monophosphate + H2O => carbovir monophosphate + cyclopropylamine (Homo sapiens)


name: abacavir + AMP => abacavir monophosphate + adenosine (Homo sapiens)


name: abacavir + UDP-glucuronate => abacavir 5'-glucuronide + UDP (Homo sapiens)


name: carbovir + IMP => carbovir monophosphate + inosine (Homo sapiens)


name: carbovir diphosphate + ATP => carbovir triphosphate + ADP (Homo sapiens)


name: carbovir + IMP => carbovir monophosphate + inosine (Mus musculus)


name: abacavir monophosphate + H2O => carbovir monophosphate + cyclopropylamine (Mus musculus)


name: abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ (Mus musculus)


name: abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ (Rattus norvegicus)


name: carbovir + IMP => carbovir monophosphate + inosine (Rattus norvegicus)


name: abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ (Canis familiaris)


name: carbovir + IMP => carbovir monophosphate + inosine (Canis familiaris)


name: abacavir monophosphate + H2O => carbovir monophosphate + cyclopropylamine (Canis familiaris)


name: carbovir + IMP => carbovir monophosphate + inosine (Bos taurus)


name: abacavir monophosphate + H2O => carbovir monophosphate + cyclopropylamine (Bos taurus)


name: abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ (Bos taurus)


name: abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ (Sus scrofa)


name: abacavir monophosphate + H2O => carbovir monophosphate + cyclopropylamine (Sus scrofa)


name: carbovir + IMP => carbovir monophosphate + inosine (Sus scrofa)


name: abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ (Danio rerio)


name: abacavir monophosphate + H2O => carbovir monophosphate + cyclopropylamine (Danio rerio)


name: Abacavir metabolism (Xenopus tropicalis)


name: abacavir monophosphate + H2O => carbovir monophosphate + cyclopropylamine (Xenopus tropicalis)


name: abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ (Xenopus tropicalis)


name: carbovir + IMP => carbovir monophosphate + inosine (Xenopus tropicalis)


name: abacavir monophosphate + H2O => carbovir monophosphate + cyclopropylamine (Gallus gallus)


name: abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ (Gallus gallus)


name: carbovir + IMP => carbovir monophosphate + inosine (Gallus gallus)


name: Abacavir metabolism (Drosophila melanogaster)


name: abacavir monophosphate + H2O => carbovir monophosphate + cyclopropylamine (Drosophila melanogaster)


name: carbovir + IMP => carbovir monophosphate + inosine (Drosophila melanogaster)


name: abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ (Drosophila melanogaster)


name: Abacavir metabolism (Caenorhabditis elegans)


name: abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ (Caenorhabditis elegans)


name: abacavir monophosphate + H2O => carbovir monophosphate + cyclopropylamine (Caenorhabditis elegans)


name: carbovir + IMP => carbovir monophosphate + inosine (Caenorhabditis elegans)


name: Abacavir metabolism (Dictyostelium discoideum)


name: carbovir + IMP => carbovir monophosphate + inosine (Dictyostelium discoideum)


name: abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ (Dictyostelium discoideum)


name: Abacavir metabolism (Schizosaccharomyces pombe)


name: abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ (Schizosaccharomyces pombe)


name: Abacavir metabolism (Saccharomyces cerevisiae)


name: abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ (Saccharomyces cerevisiae)


name: Abacavir transmembrane transport (Homo sapiens)


name: abacavir [extracellular] => abacavir [cytosol] (Homo sapiens)


name: abacavir [cytosol] + ATP + H2O => abacavir[extracellular] + ADP + phosphate (Homo sapiens)


name: Abacavir transmembrane transport (Mus musculus)


name: abacavir [extracellular] => abacavir [cytosol] (Mus musculus)


name: Abacavir transmembrane transport (Rattus norvegicus)


name: abacavir [extracellular] => abacavir [cytosol] (Rattus norvegicus)


name: Abacavir transmembrane transport (Canis familiaris)


name: abacavir [extracellular] => abacavir [cytosol] (Canis familiaris)


name: Abacavir transmembrane transport (Bos taurus)


name: abacavir [extracellular] => abacavir [cytosol] (Bos taurus)


name: Abacavir transmembrane transport (Sus scrofa)


name: abacavir [extracellular] => abacavir [cytosol] (Sus scrofa)


name: Abacavir transmembrane transport (Danio rerio)


name: abacavir [extracellular] => abacavir [cytosol] (Danio rerio)


name: Abacavir transmembrane transport (Xenopus tropicalis)


name: abacavir [extracellular] => abacavir [cytosol] (Xenopus tropicalis)


name: Abacavir transmembrane transport (Gallus gallus)


name: abacavir [extracellular] => abacavir [cytosol] (Gallus gallus)


name: Abacavir transmembrane transport (Drosophila melanogaster)


name: abacavir [extracellular] => abacavir [cytosol] (Drosophila melanogaster)


name: Abacavir transmembrane transport (Caenorhabditis elegans)


name: abacavir [extracellular] => abacavir [cytosol] (Caenorhabditis elegans)


name: Maturation of hRSV A proteins (Homo sapiens)


name: M dimer localizes to nucleus (Homo sapiens)


name: N-/O-glycan-sG is secreted (Homo sapiens)


name: Nascent sG localizes to ER lumen, gets glycosylated (Homo sapiens)


name: F0 is cleaved, releasing F1, F2, F(110-136) (Homo sapiens)


name: Mature G localizes to host cell plasma membrane (Homo sapiens)


name: Protein P tetramer binds protein L (Homo sapiens)


name: CK2 phosphorylates nascent P (Homo sapiens)


name: Nascent SH localizes to Golgi membrane (Homo sapiens)


name: NS1:NS2 (1C:1B) localizes to mitochondria (Homo sapiens)


name: p-S232-S237-P is further phosphorylated (Homo sapiens)


name: Protein M2-1 tetramers bind protein P tetramer (Homo sapiens)


name: P:PP1 dephosphorylates M2-1 (Homo sapiens)


name: M2-1 tetramer gets phosphorylated (Homo sapiens)


name: SH pentamer localizes to host cell plasma membrane (Homo sapiens)


name: Nascent N is phosphorylated (Homo sapiens)


name: NS1 (1C) binds to NS2 (1B) (Homo sapiens)


name: F1 binds to F2 forming the F subunit (Homo sapiens)


name: M dimer gets exported from nucleus (Homo sapiens)


name: Protein M2-1 forms tetramers (Homo sapiens)


name: Protein N forms hendecamers (Homo sapiens)


name: Nascent F signal peptide is cleaved at ER membrane (Homo sapiens)


name: Nascent G signal peptide is cleaved at ER membrane (Homo sapiens)


name: SH pentamer is phosphorylated (Homo sapiens)


name: M dimer is phosphorylated (Homo sapiens)


name: F subunits form trimers at plasma membrane rafts (Homo sapiens)


name: M2-1 localizes to nucleus (Homo sapiens)


name: NS2 (1B) forms a homodimer (Homo sapiens)


name: NS1 (1C) localizes to nucleus (Homo sapiens)


name: Assembly and release of respiratory syncytial virus (RSV) virions (Homo sapiens)


name: Formation of hRSV A matrix lattice (Homo sapiens)


name: Packaging of RdRP complex with replicated hRSV A nucleocapsid (Homo sapiens)


name: N protein coats hRSV genomic (-)ssRNA (Homo sapiens)


name: Budding of hRSV A virions from infected cell (Homo sapiens)


name: Translation of respiratory syncytial virus mRNAs (Homo sapiens)


name: M2 mRNA is translated into protein M2-2 (Homo sapiens)


name: F mRNA is translated into nascent protein F (Homo sapiens)


name: NS2 (1B) mRNA is translated into protein NS2 (Homo sapiens)


name: L mRNA is translated into protein L (Homo sapiens)


name: G mRNA is translated into membrane-bound G protein (Homo sapiens)


name: G mRNA is translated into nascent secreted G protein (Homo sapiens)


name: SH mRNA is translated into protein SH (Homo sapiens)


name: M2 mRNA is translated into protein M2-1 (Homo sapiens)


name: SH mRNA is translated into protein SHt (Homo sapiens)


name: P mRNA is translated into protein P (Homo sapiens)


name: N mRNA is translated into protein N (Homo sapiens)


name: NS1 (1C) mRNA is translated into protein NS1 (1C) (Homo sapiens)


name: M mRNA is translated into protein M (Homo sapiens)


name: Respiratory syncytial virus genome replication (Homo sapiens)


name: Formation of hRSV A dsRNA intermediate form (Homo sapiens)


name: Synthesis of negative sense genomic RNA of respiratory syncytial virus (Homo sapiens)


name: Packaging of antigenomic RNA of human respiratory syncytial virus (Homo sapiens)


name: Synthesis of antigenomic RNA of human respiratory syncytial virus (Homo sapiens)


name: Abortive replication of hRSV A (Homo sapiens)


name: Respiratory syncytial virus genome transcription (Homo sapiens)


name: RdRP binds hRSV nucleocapsid (Homo sapiens)


name: Transcription of respiratory syncytial virus subgenomic positive sense mRNAs (Homo sapiens)


name: L protein acts as a cap N7 methyltransferase to modify RSV mRNAs (Homo sapiens)


name: L protein acts as a cap 2'-O-methyltransferase to modify RSV mRNAs (Homo sapiens)


name: Polyadenylation of respiratory syncytial virus subgenomic positive-sense mRNAs (Homo sapiens)


name: Lumicitabine binds RdRP on nucleocapsid (Homo sapiens)


name: Respiratory syncytial virus (RSV) attachment and entry (Homo sapiens)


name: hRSV A enters host cell through macropinocytosis (Homo sapiens)


name: Release of hRSV A nucleocapsid from macropinosome (Homo sapiens)


name: F protein binds NCL on host cell surface (Homo sapiens)


name: hRSV A enters host cell through membrane fusion (Homo sapiens)


name: F inhibitors bind F on RSV virion (Homo sapiens)


name: FCGR3A-mediated IL10 synthesis (Homo sapiens)


name: CREB1 binds IL-10 promoter (Homo sapiens)


name: Opsonized leishmania amastigote binds FCGR3 (Homo sapiens)


name: IgG binds LPG1G2 in the amastigote form of Leishmania (Homo sapiens)


name: Recruitment of PLCgamma to membrane due to FCGR3A effect (Homo sapiens)


name: Release of PLCG from FCGR3A (Homo sapiens)


name: Src phosphorylate SYK in IgG:Leishmania surface:p-FCGR3A:SYK (Homo sapiens)


name: IgG binds the surface of the amastigote form of Leishmania (Homo sapiens)


name: IL10 gene produces IL10 protein (Homo sapiens)


name: Phosphorylation and activation of PLCG due to FCGR3A effect (Homo sapiens)


name: SYK binds IgG:Lma antigens:FCGR3A:p-CD3 dimers (Homo sapiens)


name: Src phosphorylates CD3 dimers in IgG:Lma antigens:FCGR3A:CD3 dimers (Homo sapiens)


name: CD163 mediating an anti-inflammatory response (Homo sapiens)


name: CD163 gene produces CD163 protein (Homo sapiens)


name: iRHOM2 transports ADAM17 from ER to the Golgi-network (Homo sapiens)


name: sCD163 translocates from extracellular region to cytosol (Homo sapiens)


name: p-S,T-ADAM17(215-827):Zn2+ cleaves CD163 (Homo sapiens)


name: PLK2, MAPK14 phosphorylate ADAM17 (Homo sapiens)


name: sCD163 binds MYH9 in T-cells (Homo sapiens)


name: iRHOM2 transports ADAM17:Zn2+ from Golgi to the plasma membrane (Homo sapiens)


name: LTC4-CYSLTR mediated IL4 production (Homo sapiens)


name: GGT1, 5 dimers hydrolyse LTC4 to LTD4 (Homo sapiens)


name: LTD4 is converted to LTE4 by DPEP1/2 (Homo sapiens)


name: ADORA2B mediated anti-inflammatory cytokines production (Homo sapiens)


name: ADORA2B:Ade-Rib binds heterometric G-protein Gs (Homo sapiens)


name: ADORA2B (in Ade-Rib:ADORA2B:Heterotrimeric G-protein Gs) exchanges GDP for GTP on Gs (Homo sapiens)


name: IL6 gene produces IL6 protein (Homo sapiens)


name: ADORA2B:Ade-Rib:GsGTP dissociates (Homo sapiens)


name: FCGR3A-mediated phagocytosis (Homo sapiens)


name: DOCK180 exchanges GTP for GDP on RAC1:GDP (Homo sapiens)


name: p-VAV1,2,3 exchanges GTP for GDP on RAC1:GDP (Homo sapiens)


name: p-6Y-SYK phosphorylates VAV1,2,3 (Homo sapiens)


name: CRKII:DOCK180:ELMO binds FCGR3A (Homo sapiens)


name: PtdIns(4,5)P2 binds WASP, N-WASP (Homo sapiens)


name: CDC42:GTP binds PtdIns(4,5)P2:WASP,N-WASP (Homo sapiens)


name: IgG binds the surface of the amastigote form of Leishmania (Homo sapiens)


name: VAV1,2,3:PI(3,4,5)P3 binds p-6Y-SYK (Homo sapiens)


name: IgG:Leishmania surface:FCGR3A translocates from plasma membrane to the parasitophorous vacuole (Homo sapiens)


name: IgG:Lma antigens binds FCGR3A:CD3 dimers (Homo sapiens)


name: WNT5:FZD7-mediated leishmania damping (Homo sapiens)


name: Activated JNK phosphorylates c-JUN (Homo sapiens)


name: p-T,Y-MAPK8 translocates from the cytosol to the nucleoplasm (Homo sapiens)


name: GTP-bound RAC1 contributes to MAPK8 activation (Homo sapiens)


name: NOX1 complex:pp-DVL:RAC1:GTP generates superoxide from oxygen (Homo sapiens)


name: ppDVL:RAC1:GTP binds NOX1 complex (Homo sapiens)


name: Unknown kinase phosphorylates p-DVL (Homo sapiens)


name: Purinergic signaling in leishmaniasis infection (Homo sapiens)


name: P2RX4,7 binds itself to form trimeric non-selective cation channels (Homo sapiens)


name: ATP translocates from cytosol to extracellular space (stimuated by C3AR1:C3a) (Homo sapiens)


name: Signaling by FGFR1 in disease (Homo sapiens)


name: Activated FGFR1 mutants:p-FRS2 binds GRB2:GAB1:PIK3R1 (Homo sapiens)


name: Activated FGFR1 mutant-associated PI3K phosphorylates PIP2 to PIP3 (Homo sapiens)


name: Activated FGFR1 mutants and fusions bind PLCG1 (Homo sapiens)


name: Activated FGFR1 mutants:p-FRS2:GRB2:GAB1:PIK3R1 binds PIK3CA (Homo sapiens)


name: Activated FGFR1 mutants:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Homo sapiens)


name: Activated FGFR1 mutants phosphorylate FRS2 (Homo sapiens)


name: Activated FGFR1 mutants and fusions phosphorylate PLCG1 (Homo sapiens)


name: Activated FGFR1 mutants:p-FRS2 binds GRB2-SOS1 (Homo sapiens)


name: Activated FGFR1 mutants bind FRS2 (Homo sapiens)


name: p-4Y- PLCG1 dissociates from activated FGFR1 mutants and fusions (Homo sapiens)


name: Signaling by cytosolic FGFR1 fusion mutants (Homo sapiens)


name: BCR-FGFR1-associated PI3K phosphorylates PIP2 to PIP3. (Homo sapiens)


name: FGFR1OP-FGFR1 phosphorylates STAT1 and STAT3 (Homo sapiens)


name: p-BCR-p-FGFR1 phosphorylates GAB2 (Homo sapiens)


name: Cytosolic FGFR1 fusion proteins bind PIK3R1 (Homo sapiens)


name: BCR-FGFR1:GRB2:p-GAB2 binds PIK3R1 (Homo sapiens)


name: Phosphorylation of STAT5 by cytosolic FGFR1 fusions (Homo sapiens)


name: Activated cytosolic FGFR1 fusions bind PIK3CA (Homo sapiens)


name: Cytosolic FGFR1 fusion protein-associated PI3K phosphorylates PIP2 to PIP3 (Homo sapiens)


name: p-BCR-pFGFR1 binds GRB2:GAB2 (Homo sapiens)


name: Dimerization of cytosolic FGFR1 fusion proteins (Homo sapiens)


name: Phosphorylation of BCR moiety of BCR-FGFR1 (Homo sapiens)


name: Phosphorylation of cytosolic FGFR1 fusion dimers (Homo sapiens)


name: Tyrosine kinase inhibitors bind and inhibit cytosolic FGFR1 fusion dimer phosphorylation (Homo sapiens)


name: BCR-FGFR1 fusion:GRB2:p-GAB2:PIK3R1 binds PIK3CA  (Homo sapiens)


name: Signaling by FGFR1 amplification mutants (Homo sapiens)


name: Ligand-independent dimerization of overexpressed FGFR1b (Homo sapiens)


name: Ligand-independent phosphorylation of overexpressed FGFR1 (Homo sapiens)


name: Tyrosine kinase inhibitors bind and inhibit overexpressed FGFR1 dimers (Homo sapiens)


name: Ligand-independent phosphorylation of overexpressed FGFR1c (Homo sapiens)


name: Ligand-independent dimerization of overexpressed FGFR1c (Homo sapiens)


name: Signaling by activated point mutants of FGFR1 (Homo sapiens)


name: Dimerization of FGFR1 point mutants with enhanced kinase activity (Homo sapiens)


name: Autocatalytic phosphorylation of FGFR1 mutants with enhanced kinase activity (Homo sapiens)


name: FGFR1c P252X mutants bind ligand with enhanced affinity (Homo sapiens)


name: Autocatalytic phosphorylation of FGFR1c P252X mutant dimers (Homo sapiens)


name: Signaling by plasma membrane FGFR1 fusions (Homo sapiens)


name: Plasma membrane FGFR1 fusions dimerize (Homo sapiens)


name: Plasma membrane FGFR1 fusions autophosphorylate (Homo sapiens)


name: Signaling by FGFR3 in disease (Homo sapiens)


name: Activated FGFR3 point, translocation and fusion mutants phosphorylate FRS2 (Homo sapiens)


name: Activated FGFR3 point, translocation and fusion mutants:p-FRS2:GRB2:GAB1:PIK3R1 binds PIK3CA (Homo sapiens)


name: FGFR3 mutants bind and are inactivated by tyrosine kinase inhibitors (Homo sapiens)


name: Activated FGFR3 point, translocation and fusion mutants:p-FRS2 binds GRB2:GAB1:PIK3R1 (Homo sapiens)


name: Activated FGFR3 point, translocation and fusion mutants bind FRS2 (Homo sapiens)


name: Activated FGFR3 point, translocation and fusion mutants:p-FRS2 binds GRB2-SOS1 (Homo sapiens)


name: p-4Y-PLCG1 dissociates from activated FGFR3 point and translocation mutants (Homo sapiens)


name: Activated FGFR3 point and translocation mutants bind PLCG1 (Homo sapiens)


name: Activated FGFR3 point, translocation and fusion mutants:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Homo sapiens)


name: Activated FGFR3 point and translocation mutants phosphorylate PLCG1 (Homo sapiens)


name: Activated FGFR3 point, translocation and fusion mutant-associated PI3K phosphorylates PIP2 to PIP3 (Homo sapiens)


name: Signaling by FGFR3 fusions in cancer (Homo sapiens)


name: Autocatalytic phosphorylation of FGFR3 fusions (Homo sapiens)


name: t(4;14) translocations of FGFR3 (Homo sapiens)


name: Dimerization of FGFR3 t(4;14) translocation mutants (Homo sapiens)


name: Autocatalytic phosphorylation of FGFR3 t(4;14) translocation mutants (Homo sapiens)


name: Signaling by activated point mutants of FGFR3 (Homo sapiens)


name: Autocatalytic phosphorylation of FGFR3 cysteine mutants (Homo sapiens)


name: Dimerization of FGFR3 point mutants with enhanced kinase activity (Homo sapiens)


name: Constitutive dimerization of FGFR3 cysteine mutants (Homo sapiens)


name: Autocatalytic phosphorylation of FGFR3c P250R mutant (Homo sapiens)


name: FGFR3c P250R mutant binds to ligand with enhanced affinity (Homo sapiens)


name: Autocatalytic phosphorylation of FGFR3 point mutants with enhanced kinase activity (Homo sapiens)


name: Signaling by FGFR2 in disease (Homo sapiens)


name: Activated FGFR2 mutants:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Homo sapiens)


name: Activated FGFR2 mutants:p-FRS2 binds GRB2:GAB1:PIK3R1 (Homo sapiens)


name: Activated FGFR2 mutant-associated PI3K phosphorylates PIP2 to PIP3 (Homo sapiens)


name: Activated FGFR2 mutants bind FRS2 (Homo sapiens)


name: Activated FGFR2 mutants:p-FRS2:GRB2:GAB1:PIK3R1 binds PIK3CA (Homo sapiens)


name: p-4Y-PLCG1 dissociates from activated FGFR2 mutants (Homo sapiens)


name: Activated FGFR2 mutants bind PLCG1 (Homo sapiens)


name: Activated FGFR2 mutants:p-FRS2 binds GRB2-SOS1 (Homo sapiens)


name: Activated FGFR2 mutants phosphorylate PLCG1 (Homo sapiens)


name: Activated FGFR2 mutants phosphorylate FRS2 (Homo sapiens)


name: Activated point mutants of FGFR2 (Homo sapiens)


name: Point mutants of FGFR2 bind and are inactivated by tyrosine kinase inhibitors (Homo sapiens)


name: FGFR2c mutants bind an expanded range of ligands (Homo sapiens)


name: Autocatalytic phosphorylation of FGFR2b mutants with enhanced ligand binding (Homo sapiens)


name: Autocatalytic phosphorylation of FGFR2 ligand-independent  mutants (Homo sapiens)


name: Autocatalytic phosphorylation of FGFR2 point mutants with enhanced kinase activity (Homo sapiens)


name: FGFR2b mutants bind an expanded range of ligands (Homo sapiens)


name: Dimerization of FGFR2 point mutants with enhanced kinase activity (Homo sapiens)


name: FP-1039 acts as a ligand-trap for FGFR2b-binding ligands in endometrial cancer (Homo sapiens)


name: Autocatalytic phosphorylation of FGFR2c mutants with enhanced ligand binding (Homo sapiens)


name: Dimerization of FGFR2 ligand-independent mutants (Homo sapiens)


name: Signaling by FGFR2 fusions (Homo sapiens)


name: FGFR2 fusions autophosphorylate (Homo sapiens)


name: Signaling by FGFR2 amplification mutants (Homo sapiens)


name: GP369 inhibits activation of amplified FGFR2 signaling (Homo sapiens)


name: Autocatalytic phosphorylation of overexpressed FGFR2 variants (Homo sapiens)


name: Dimerization of overexpressed FGFR2 (Homo sapiens)


name: Tyrosine kinase inhibitors bind to overexpressed FGFR2 variants (Homo sapiens)


name: Signaling by FGFR2 IIIa TM (Homo sapiens)


name: FGFR2IIIa TM binds ligand and full length receptors to inhibit signaling (Homo sapiens)


name: Aberrant alternative splicing yields a secreted FGFR2 IIIa TM disease variant (Homo sapiens)


name: Signaling by FGFR4 in disease (Homo sapiens)


name: p-4Y-PLCG1 dissociates from activated FGFR4 mutants (Homo sapiens)


name: Activated FGFR4 mutants phosphorylate PLCG1 (Homo sapiens)


name: Activated FGFR4 mutants bind PLCG1 (Homo sapiens)


name: Activated FGFR4 mutants:p-FRS2 binds GRB2:GAB1:PIK3R1 (Homo sapiens)


name: Activated FGFR4 mutant-associated PI3K phosphorylates PIP2 to PIP3 (Homo sapiens)


name: Activated FGFR4 mutants:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Homo sapiens)


name: Activated FGFR4 mutants:p-FRS2:GRB2:GAB1:PIK3R1 binds PIK3CA (Homo sapiens)


name: Activated FGFR4 mutants:p-FRS2 binds GRB2-SOS1 (Homo sapiens)


name: Activated FGFR4 mutants phosphorylate FRS2 (Homo sapiens)


name: Activated FGFR4 mutants bind FRS2 (Homo sapiens)


name: FGFR4 mutant receptor activation (Homo sapiens)


name: Autocatalytic phosphorylation of FGFR4 mutants with enhanced kinase activity (Homo sapiens)


name: Dimerization of FGFR4 mutants with enhanced kinase activity (Homo sapiens)


name: Autocatalytic phosphorylation of FGFR4 Y367C mutant (Homo sapiens)


name: Constitutive dimerization of FGFR4 Y367C mutant (Homo sapiens)


name: FGFR4 kinase mutants are inhibited by PD170734 (Homo sapiens)


name: KIT mutants bind type II TKIs (Homo sapiens)


name: KIT mutants bind type I TKIs (Homo sapiens)


name: KIT mutants bind ripretinib (Homo sapiens)


name: Sorafenib-resistant KIT mutants (Homo sapiens)


name: Sorafenib-resistant KIT mutants do not bind sorafenib (Homo sapiens)


name: Nilotinib-resistant KIT mutants (Homo sapiens)


name: Nilotinib-resistant KIT mutants do not bind nilotinib (Homo sapiens)


name: Masitinib-resistant KIT mutants (Homo sapiens)


name: Masitinib-resistant KIT mutants do not bind masitinib (Homo sapiens)


name: Dasatinib-resistant KIT mutants (Homo sapiens)


name: Dasatinib-resistant KIT mutants do not bind dasatinib (Homo sapiens)


name: Regorafenib-resistant KIT mutants (Homo sapiens)


name: Regorafenib-resistant KIT mutants do not bind regorafenib (Homo sapiens)


name: Sunitinib-resistant KIT mutants (Homo sapiens)


name: Sunitinib-resistant KIT mutants do not bind sunitinib (Homo sapiens)


name: Imatinib-resistant KIT mutants (Homo sapiens)


name: Imatinib-resistant KIT mutants do not bind imatinib (Homo sapiens)


name: Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants (Homo sapiens)


name: Phosphorylation of STATs downstream of KIT mutants (Homo sapiens)


name: KIT mutants bind GRB2-SOS (Homo sapiens)


name: JAK2 binds to p-KIT mutants (Homo sapiens)


name: Phosphorylated KIT mutants bind PI3K (Homo sapiens)


name: Disassociation and translocation of STATs to the nucleus downstream of KIT mutants (Homo sapiens)


name: p-KIT mutants:GRB2:SOS catalyzes nucleotide exchange on RAS (Homo sapiens)


name: Recruitment of STATs by KIT mutants (Homo sapiens)


name: Dimerization of STATs downstream of KIT mutants (Homo sapiens)


name: KIT mutants:PI3K catalyze synthesis of PIP3 (Homo sapiens)


name: Phosphorylation of JAK2 downstream of KIT mutants (Homo sapiens)


name: Signaling by extracellular domain mutants of KIT (Homo sapiens)


name: Phosphorylation of extracellular domain KIT mutants (Homo sapiens)


name: Ligand-independent dimerization of KIT extracellular domain mutants (Homo sapiens)


name: Signaling by juxtamembrane domain KIT mutants (Homo sapiens)


name: Phosphorylation of juxtamembrane domain KIT mutants (Homo sapiens)


name: Ligand-independent dimerization of KIT juxtamembrane domain mutants (Homo sapiens)


name: Signaling by kinase domain mutants of KIT (Homo sapiens)


name: Constitutive phosphorylation of kinase domain KIT mutants (Homo sapiens)


name: Signaling by LRP5 mutants  (Homo sapiens)


name: misspliced mutants of LRP5 support enhanced beta-catenin-dependent signaling (Homo sapiens)


name: Signaling by GSK3beta mutants (Homo sapiens)


name: Misspliced GSK3beta mutants stabilize beta-catenin levels (Homo sapiens)


name: Signaling by TCF7L2 mutants (Homo sapiens)


name: TFC7L2 mutants don't bind CTBP (Homo sapiens)


name: CTNNB1 T41 mutants aren't phosphorylated (Homo sapiens)


name: CTNNB1 T41 mutants aren't phosphorylated by GSK3beta (Homo sapiens)


name: CTNNB1 S33 mutants aren't phosphorylated (Homo sapiens)


name: CTNNB1 S33 mutants aren't phosphorylated by GSK3beta (Homo sapiens)


name: CTNNB1 S37 mutants aren't phosphorylated (Homo sapiens)


name: CTNNB1 S37 mutants aren't phosphorylated by GSK3beta (Homo sapiens)


name: CTNNB1 S45 mutants aren't phosphorylated (Homo sapiens)


name: CTNNB1 S45 mutants aren't phosphorylated by CK1alpha (Homo sapiens)


name: XAV939 binds tankyrase to stabilize axin and inhibit WNT signaling (Homo sapiens)


name: APC truncation mutants are not K63 polyubiquitinated (Homo sapiens)


name: APC truncation mutants have impaired AXIN binding (Homo sapiens)


name: PORCN-inhibitor LGK974 prevents WNT ligand palmitoyltation and secretion (Homo sapiens)


name: Truncations of AMER1 destabilize the destruction complex (Homo sapiens)


name: Truncated AMER1 mutants destabilize the destruction complex (Homo sapiens)


name: Deletions in the AMER1 gene destabilize the destruction complex (Homo sapiens)


name: Deletions of the AMER1 gene prevent expression of AMER1 protein (Homo sapiens)


name: Signaling by RNF43 mutants (Homo sapiens)


name: RNF43 frameshift mutants show enhanced WNT siganling (Homo sapiens)


name: Deletions in the AXIN1 gene destabilize the destruction complex (Homo sapiens)


name: Deletions in the AXIN1 gene prevent expression of AXIN1 protein (Homo sapiens)


name: AXIN missense mutants destabilize the destruction complex (Homo sapiens)


name: AXIN mutants destabilize the destruction complex (Homo sapiens)


name: Signaling by FLT3 ITD and TKD mutants (Homo sapiens)


name: FLT3 mutants:GRB2:SOS1-mediated nucleotide exchange on RAS (Homo sapiens)


name: FLT3 mutants recruit PIK3CA through PIK3R1 (Homo sapiens)


name: Ligand-independent dimerization of FLT3 mutants (Homo sapiens)


name: FLT3 mutants:GRB2:p-Y-GAB2 binds PTPN11 (Homo sapiens)


name: Constitutive phosphorylation of FLT3 mutants (Homo sapiens)


name: FLT3 mutant dimers:GRB2 bind SOS1 (Homo sapiens)


name: FLT3 mutants:GRB2 bind GAB2 (Homo sapiens)


name: FLT3 mutant dimers bind GRB2 (Homo sapiens)


name: FLT3 mutants recruit PIK3R1 through phosphorylated GAB2 (Homo sapiens)


name: FLT3 mutants phosphorylate GAB2 (Homo sapiens)


name: STAT5 activation downstream of FLT3 ITD mutants (Homo sapiens)


name: p-STAT5 dissociates from mutant FLT3 (Homo sapiens)


name: FLT3 ITD- and STAT5-dependent NOX4 gene expression (Homo sapiens)


name: FLT3 ITD- and STAT5-dependent BCL2L1 gene expression (Homo sapiens)


name: STAT5-dependent PIM1 gene expression downstream of FLT3 ITD and fusion mutants (Homo sapiens)


name: PTPN11:p-STAT5 binds BCL2L1 promoter (Homo sapiens)


name: FLT3 ITD- and NOX4-dependent H2O2 production (Homo sapiens)


name: PTPN11:p-STAT5 translocates to nucleus downstream of mutant FLT3 (Homo sapiens)


name: p-STAT5 binds the NOX4 promoter (Homo sapiens)


name: PTPN11:p-STAT5 dissociates from mutant FLT3 (Homo sapiens)


name: p-STAT5 binds the CDKN1A gene (Homo sapiens)


name: FLT3 ITD- and STAT5-dependent CDKN1A gene expression (Homo sapiens)


name: FLT3 ITD mutants phosphorylate STAT5 (Homo sapiens)


name: FLT3 ITD mutants bind STAT5 through GAB2:PTPN11 (Homo sapiens)


name: p-STAT5 translocates to nucleus downstream of mutant FLT3 (Homo sapiens)


name: GAB2 in Active FLT3:GRB2:GAB2 is phosphorylated (Homo sapiens)


name: FLT3LG dimer:FLT3 dimer autophosphorylates (Homo sapiens)


name: Active FLT3 binds to GRB10 (Homo sapiens)


name: Active FLT3 dimer binds GRB2 (Homo sapiens)


name: Active FLT3:GRB2:p-Y-GAB2 binds PTPN11 (Homo sapiens)


name: Active FLT3 binds to GRAP2 (Homo sapiens)


name: FLT3LG dimer:FLT3 binds FLT3 (Homo sapiens)


name: Active FLT3:GRB2 binds SOS1 (Homo sapiens)


name: SOS1-mediated nucleotide exchange of RAS downstream of FLT3 (Homo sapiens)


name: FOXO3-dependent BCL2L11 gene expression (Homo sapiens)


name: FOXO3-dependent CDKN1B gene expression (Homo sapiens)


name: Active FLT3:GRB2:p-GAB2:PIK3R1 binds PIK3CA (Homo sapiens)


name: AKT-phosphorylated FOXO3 translocates to cytosol (Homo sapiens)


name: Active FLT3:GRB2:p-Y-GAB2 binds PIK3R1 (Homo sapiens)


name: Active FLT3 phosphorylates CDKN1B (Homo sapiens)


name: AKT phosphorylates FOXO3 downstream of FLT3  (Homo sapiens)


name: Active FLT3:p-Y-GRB10 binds PIK3R1 (Homo sapiens)


name: Active FLT3:GRB2 binds GAB2 (Homo sapiens)


name: FLT3 phosphorylates GRB10 (Homo sapiens)


name: Active FLT3:p-Y GRB10:PIK3R1 binds PIK3CA (Homo sapiens)


name: FLT3 signaling through SRC family kinases (Homo sapiens)


name: FLT3 signaling through SRC family kinases (Mus musculus)


name: FLT3 signaling through SRC family kinases (Canis familiaris)


name: Active FLT3 binds to LCK (Canis familiaris)


name: Active FLT3 binds to SYK (Canis familiaris)


name: FLT3 signaling through SRC family kinases (Bos taurus)


name: FLT3 signaling through SRC family kinases (Sus scrofa)


name: Negative regulation of FLT3 (Homo sapiens)


name: Active FLT3 binds to SH2B3 (Homo sapiens)


name: Active FLT3 binds to SOCS6 (Homo sapiens)


name: Active FLT3 binds to SOCS2 (Homo sapiens)


name: Active FLT3 binds to ABL2 (Homo sapiens)


name: PTPRJ dephosphorylates active FLT3 (Homo sapiens)


name: Internalization of ubiquitinated FLT3 (Homo sapiens)


name: Active FLT3 binds to SLA2 (Homo sapiens)


name: Negative regulation of FLT3 (Mus musculus)


name: Active FLT3 binds to SH2B3 (Mus musculus)


name: Internalization of ubiquitinated FLT3 (Mus musculus)


name: Active FLT3 binds to SOCS6 (Mus musculus)


name: Active FLT3 binds to ABL2 (Mus musculus)


name: Active FLT3 binds to SOCS2 (Mus musculus)


name: Active FLT3 binds to SLA2 (Mus musculus)


name: PTPRJ dephosphorylates active FLT3 (Mus musculus)


name: Negative regulation of FLT3 (Canis familiaris)


name: Internalization of ubiquitinated FLT3 (Canis familiaris)


name: Active FLT3 binds to SOCS6 (Canis familiaris)


name: Active FLT3 binds to CSK (Canis familiaris)


name: Active FLT3 binds to SLA (Canis familiaris)


name: Ubiquitination of FLT3 (Canis familiaris)


name: Active FLT3 binds to SH2B3 (Canis familiaris)


name: PTPRJ dephosphorylates active FLT3 (Canis familiaris)


name: FLT3 phosphorylates CBL (Canis familiaris)


name: Active FLT3 binds to SLA2 (Canis familiaris)


name: Active FLT3 binds to CBL (Canis familiaris)


name: Active FLT3 binds to ABL2 (Canis familiaris)


name: Active FLT3 binds to SOCS2 (Canis familiaris)


name: Negative regulation of FLT3 (Bos taurus)


name: PTPRJ dephosphorylates active FLT3 (Bos taurus)


name: Internalization of ubiquitinated FLT3 (Bos taurus)


name: Negative regulation of FLT3 (Sus scrofa)


name: Internalization of ubiquitinated FLT3 (Sus scrofa)


name: p-STAT5 dissociates from activator:STAT5 complex (Homo sapiens)


name: Activator phosphorylates STAT5 (Homo sapiens)


name: SOS1-mediated nucleotide exchange of RAS downstream of FLT3 (Mus musculus)


name: Active FLT3:p-Y GRB10:PIK3R1 binds PIK3CA (Mus musculus)


name: Active FLT3:GRB2 binds SOS1 (Mus musculus)


name: AKT-phosphorylated FOXO3 translocates to cytosol (Mus musculus)


name: FLT3 phosphorylates GRB10 (Mus musculus)


name: AKT phosphorylates FOXO3 downstream of FLT3  (Mus musculus)


name: Active FLT3 binds to GRB10 (Mus musculus)


name: FLT3LG dimer:FLT3 dimer autophosphorylates (Mus musculus)


name: Active FLT3:GRB2:p-GAB2:PIK3R1 binds PIK3CA (Mus musculus)


name: Active FLT3 phosphorylates CDKN1B (Mus musculus)


name: Active FLT3:p-Y-GRB10 binds PIK3R1 (Mus musculus)


name: FLT3LG dimer:FLT3 binds FLT3 (Mus musculus)


name: Active FLT3 binds to GRAP2 (Mus musculus)


name: AKT-phosphorylated FOXO3 translocates to cytosol (Rattus norvegicus)


name: AKT phosphorylates FOXO3 downstream of FLT3  (Rattus norvegicus)


name: Active FLT3:GRB2:p-GAB2:PIK3R1 binds PIK3CA (Rattus norvegicus)


name: SOS1-mediated nucleotide exchange of RAS downstream of FLT3 (Rattus norvegicus)


name: Active FLT3:p-Y GRB10:PIK3R1 binds PIK3CA (Rattus norvegicus)


name: FLT3LG dimer:FLT3 binds FLT3 (Canis familiaris)


name: FLT3LG dimer:FLT3 dimer autophosphorylates (Canis familiaris)


name: FLT3LG dimer binds FLT3 (Canis familiaris)


name: Active FLT3:GRB2:p-GAB2:PIK3R1 binds PIK3CA (Canis familiaris)


name: Active FLT3 binds to GRAP2 (Canis familiaris)


name: Active FLT3 phosphorylates CDKN1B (Canis familiaris)


name: Active FLT3 binds to GRB10 (Canis familiaris)


name: Active FLT3:p-Y-GRB10 binds PIK3R1 (Canis familiaris)


name: AKT-phosphorylated FOXO3 translocates to cytosol (Canis familiaris)


name: FLT3 phosphorylates GRB10 (Canis familiaris)


name: Active FLT3:GRB2 binds SOS1 (Canis familiaris)


name: Active FLT3:p-Y GRB10:PIK3R1 binds PIK3CA (Canis familiaris)


name: SOS1-mediated nucleotide exchange of RAS downstream of FLT3 (Canis familiaris)


name: SOS1-mediated nucleotide exchange of RAS downstream of FLT3 (Bos taurus)


name: Active FLT3 phosphorylates CDKN1B (Bos taurus)


name: AKT-phosphorylated FOXO3 translocates to cytosol (Bos taurus)


name: Active FLT3:p-Y-GRB10 binds PIK3R1 (Bos taurus)


name: FLT3LG dimer:FLT3 dimer autophosphorylates (Bos taurus)


name: Active FLT3:p-Y GRB10:PIK3R1 binds PIK3CA (Bos taurus)


name: Active FLT3:GRB2:p-GAB2:PIK3R1 binds PIK3CA (Bos taurus)


name: FLT3LG dimer:FLT3 binds FLT3 (Bos taurus)


name: Active FLT3:GRB2 binds SOS1 (Bos taurus)


name: FLT3LG dimer:FLT3 dimer autophosphorylates (Sus scrofa)


name: Active FLT3:GRB2:p-GAB2:PIK3R1 binds PIK3CA (Sus scrofa)


name: Active FLT3:p-Y-GRB10 binds PIK3R1 (Sus scrofa)


name: Active FLT3 phosphorylates CDKN1B (Sus scrofa)


name: Active FLT3:GRB2 binds SOS1 (Sus scrofa)


name: AKT-phosphorylated FOXO3 translocates to cytosol (Sus scrofa)


name: SOS1-mediated nucleotide exchange of RAS downstream of FLT3 (Sus scrofa)


name: Active FLT3:p-Y GRB10:PIK3R1 binds PIK3CA (Sus scrofa)


name: FLT3LG dimer:FLT3 binds FLT3 (Sus scrofa)


name: AKT-phosphorylated FOXO3 translocates to cytosol (Danio rerio)


name: AKT phosphorylates FOXO3 downstream of FLT3  (Danio rerio)


name: Active FLT3:GRB2:p-GAB2:PIK3R1 binds PIK3CA (Xenopus tropicalis)


name: Active FLT3:p-Y GRB10:PIK3R1 binds PIK3CA (Xenopus tropicalis)


name: SOS1-mediated nucleotide exchange of RAS downstream of FLT3 (Xenopus tropicalis)


name: AKT-phosphorylated FOXO3 translocates to cytosol (Xenopus tropicalis)


name: SOS1-mediated nucleotide exchange of RAS downstream of FLT3 (Gallus gallus)


name: Active FLT3:p-Y GRB10:PIK3R1 binds PIK3CA (Gallus gallus)


name: Active FLT3:GRB2:p-GAB2:PIK3R1 binds PIK3CA (Gallus gallus)


name: AKT phosphorylates FOXO3 downstream of FLT3  (Gallus gallus)


name: AKT-phosphorylated FOXO3 translocates to cytosol (Gallus gallus)


name: FLT3 Signaling (Drosophila melanogaster)


name: AKT phosphorylates FOXO3 downstream of FLT3  (Drosophila melanogaster)


name: SOS1-mediated nucleotide exchange of RAS downstream of FLT3 (Drosophila melanogaster)


name: AKT-phosphorylated FOXO3 translocates to cytosol (Drosophila melanogaster)


name: AKT phosphorylates FOXO3 downstream of FLT3  (Caenorhabditis elegans)


name: SOS1-mediated nucleotide exchange of RAS downstream of FLT3 (Caenorhabditis elegans)


name: AKT-phosphorylated FOXO3 translocates to cytosol (Caenorhabditis elegans)


name: FLT mutants bind type II TKIs (Homo sapiens)


name: FLT mutants bind type I TKIs (Homo sapiens)


name: FLT3 signaling by CBL mutants (Homo sapiens)


name: CBL mutants don't ubiquitinate FLT3 (Homo sapiens)


name: Signaling by FLT3 fusion proteins (Homo sapiens)


name: FLT3 fusions activate STAT5 (Homo sapiens)


name: FLT3 fusions recruit PIK3CA through PIK3R1 (Homo sapiens)


name: Ligand-independent dimerization of FLT3 fusion proteins (Homo sapiens)


name: p-STAT5 dissociates from FLT3 fusion proteinsp- (Homo sapiens)


name: FLT3 fusions recruit PIK3R1 through phosphorylated GAB2 (Homo sapiens)


name: FLT3 fusions phosphorylate GAB2 (Homo sapiens)


name: FLT3 fusion dimers autophosphorylate (Homo sapiens)


name: FLT3 fusions:GRB2 bind SOS1 (Homo sapiens)


name: Phosphorylated FLT3 fusions bind GRB2 (Homo sapiens)


name: SOS1-mediated nucleotide exchange of RAS downstream of FLT3 fusion mutants (Homo sapiens)


name: FLT3 fusions:GRB2 bind GAB2 (Homo sapiens)


name: crenolanib-resistant FLT3 mutants (Homo sapiens)


name: crenolanib-resistant FLT3 mutants don't bind crenolanib (Homo sapiens)


name: ponatinib-resistant FLT3 mutants (Homo sapiens)


name: ponatinib-resistant FLT3 mutants don't bind ponatinib (Homo sapiens)


name: linifanib-resistant FLT3 mutants (Homo sapiens)


name: linafinib-resistant FLT3 mutants don't bind linifanib (Homo sapiens)


name: semaxanib-resistant FLT3 mutants (Homo sapiens)


name: semaxanib-resistant FLT3 mutants don't bind semaxanib<br> (Homo sapiens)