metcamifen

An N-sulfonylcarboxamide resulting from the formal condensation of the sulfamoyl group of 4-[(methylcarbamoyl)amino]benzene-1-sulfonamide with the carboxy group of 2-methoxybenzoic acid. It is a herbicide safener applied as a seed treatment in sorghum.


name: 2-[(2S,3R,6R)-3-benzamido-2-(hydroxymethyl)-3,6-dihydro-2H-pyran-6-yl]acetic acid methyl ester


(S,S)-labetalol

A 2-hydroxy-5-{1-hydroxy-2-[(4-phenylbutan-2-yl)amino]ethyl}benzamide that has 1S,2S-configuration.


name: 2-[[(3-methylphenyl)-oxomethyl]amino]benzoic acid (3,5-dimethyl-4-isoxazolyl)methyl ester


name: 3-(1,3-dioxo-2-isoindolyl)propanoic acid [4-[(4-methylanilino)-oxomethyl]phenyl] ester


ACECAINIDE

A benzamide obtained via formal condensation of 4-acetamidobenzoic acid and 2-(diethylamino)ethylamine.


A dicarboximide having an endo bridged phthalimide structure, substituted at nitrogen by a 4-(quinolin-8-ylcarbamoyl)benzoyl group.


name: 2-(4-chloro-3-methylphenoxy)acetic acid [4-[(4-methylanilino)-oxomethyl]phenyl] ester


name: 2-[4-[[(3-chlorophenyl)-oxomethyl]amino]phenyl]propanedioic acid dimethyl ester


An aza-steroid that is (8xi,9xi,14xi)-androsta-5,16-diene substituted by (4-fluorobenzoyl)amino and 4-methyl-1H-imidazol-1-yl groups at positions 3S and 17, respectively. It is a potent anti-cancer agent that inhibits androgen synthesis and CYP17A1.


name: 2-[(2R,3R,6S)-3-benzamido-2-(hydroxymethyl)-3,6-dihydro-2H-pyran-6-yl]acetic acid methyl ester


N-benzoyl-L-phenylalaninol

A member of the class of benzamides resulting from the formal condensation of the carboxy group of benzoic acid with the amino group of L-phenylalaninol.


procainamide

A benzamide that is 4-aminobenzamide substituted on the amide N by a 2-(diethylamino)ethyl group.  It is a pharmaceutical antiarrhythmic agent used for the medical treatment of cardiac arrhythmias.


name: 3-[3-[2-(2-carbamoylphenoxy)-1-oxoethyl]-2,5-dimethyl-1-pyrrolyl]propanoic acid methyl ester


TRIBROMSALAN

A salicylanilide derivative with bromo- substituents at C-3 and C-5 of the salicylate moiety and at C-4 of the anilide moiety.


(R)-proglumide

The (R)-enantiomer of the racemic drug proglumide.


name: 2-(4-chloro-2-methylphenoxy)acetic acid [4-[(4-methylanilino)-oxomethyl]phenyl] ester


name: N,N-dimethylsulfamic acid [3-[(4-methoxyanilino)-oxomethyl]phenyl] ester


exalamide

An benzamide that is salicylamide in which the phenolic hydroxy group has been converted into the corresponding hexyl ether. It has been used as a topical antifungal agent.


name: acetic acid [2-[anilino(oxo)methyl]phenyl] ester


A dicarboxylic acid diamide obtained by condensation of the 3- and 4'-carboxy groups of 6-methyl[1,1'-biphenyl]-3,4'-dicarboxylic acid with cyclpropylamine and cyclpropylmethylamine respectively.


sirtinol

A benzamide obtained by formal condensation of the carboxy group of 2-{[(2-hydroxy-1-naphthyl)methylene]amino}benzoic acid with the amino group of 1-phenylethylamine.


A teichoic acid consisting of 2-O-L-alanyl-4-O-substituted-D-ribitol units connected via 1->5 phosphodiester linkages.


poly(deoxythymidylic acid)

A polynucleotide comprised of 2'-deoxythymidine units connected via 3'->5' phosphodiester linkages.


A branched polysaccharide derivative composed of a backbone of repeating N-acetyl-beta-D-glucosaminyl-(1->4)-alpha-D-rhamnosyl-(1->3)-alpha-D-rhamnosyl-(1->2)-alpha-D-rhamnosyl-(1->2)-alpha-D-rhamnosyl units, joined by (1->3)-linkages, as shown.


indolocarbazole

Compounds based upon an indolo[2,3-a]carbazole skeleton.


An indolocarbazole compound having methoxy groups at positions 3 and 9 and an additional fused pyrrolidine-2,5-dione ring. It is an inhibitor of BRSK2 kinase, PDGF-dependent receptor autophosphorylation and cell proliferation.


7-oxo-3,8,9-trihydroxy staurosporine

A indolocarbazole alkaloid that is staurosporine substituted by hydroxy groups at positions 3, 8 and 9 and an oxo group at position 7. Isolated from Cystodytes solitus, it exhibits cytotoxic activity.


A indolocarbazole alkaloid that is 4'-N-demethyl staurosporine substituted by hydroxy groups at positions 8 and 9 and an xo group at position 7. Isolated from Cystodytes solitus, it exhibits antineoplastic activity.


linkable staurosporine analogue

An analogue of staurosporine where the N-methyl group is replaced by a long-chain acyl group.


A branched amino decasaccharide consisting of a beta-D-GlcNAc residue at the reducing end with a beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)]-[beta-D-Xyl-(1->2)]-beta-D-Man-(1->4)-beta-D-GlcNAc moiety attached via a beta-(1->4)-linkage and two alpha-L-Fuc residues attached via alpha-(1->3)- and alpha-(1->6)-linkages.


Any glycoside derived from beta-D-galactosyl-(1->4)-[alpha-L-fucosyl-(1->3)]-N-acetyl-beta-D-glucosamine


connective tissue cell

category: biolink:Cell biolink:AnatomicalEntity biolink:PhysicalEssence biolink:OrganismalEntity biolink:SubjectOfInvestigation biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: A cell of the supporting or framework tissue of the body, arising chiefly from the embryonic mesoderm and including adipose tissue, cartilage, and bone.


stromal cell

description: A connective tissue cell of an organ found in the loose connective tissue. These are most often associated with the uterine mucosa and the ovary as well as the hematopoietic system and elsewhere.


perineurial cell

description: A glial cell that is part of the perineurium. This cell type has thin long bipolar cytoplasmic processes, pinocytotic vesicles, fragments of external lamina and/or external lamina-like material, attachment plaques, and desmosome-like junctions. Perineurial cells historically have been referred to as fibroblasts because of shape; however, unlike fibroblasts, a perineurial cell: does not have a compact nucleus and large endoplasmic reticulum; does have a double basement membrane opposed to a single basal lamina; is carefully joined to other perineurial cells by tight junctions into a single sheet as opposed to arranged in a large mass; and finally, can surround a small axon bundle at a nerve terminal whereas a fibroblast cannot.


glycosyl glycoside derivative

A disaccharide derivative that is formally obtained from a glycosyl glycoside.


A glycosyl glycoside derivative consisting of a 2-amino-2-deoxy-D-glucopyranose residue and a D-galactopyranose residue joined in sequence by a (1<->1) glycosidic bond.


A glycsyl glycoside derivative that is 2-amino-2-deoxy-beta-D-glucopyranose in which the anomeric hydroxy group has been converted into the corresponding beta-D-galactopyranoside.


A glycosyl glycoside derivative that is 2-acetamido-2-deoxy-alpha-D-glucopyranose in which the anomeric hydroxy group has been converted into the corresponding alpha-D-glucopyranosyl derivative.


name: alpha,alpha-trehalose dicarboxylic acid bis-N,N-dioctadecylamide

description: A dicarboxylic acid diamide obtained by formal condensation of one molecule of alpha,alpha-trehalose dicarboxylic acid and two molecules of dioctadecylamine.


An amino disaccharide consisting of an alpha-D-glucopyranose residue and a 2-acetamido-2-deoxy-D-glucopyranose residue joined in sequence by a (1->4) glycosidic bond.


An amino disaccharide consisting of alpha- and beta-D-kanosaminyl residues joined by a (1<->1)-linkage.


A glycosyl glycoside derivative consisting of 2-amino-2-desoy-alpha-D-glucopyranose and beta-D-galactopyranose residues joined by a (1->1) glycosidic bond


A glycosyl glycoside derivative consisting of consisting of beta-D-glucosamine and alpha-D-glucopyranose residues joined by a (1->1) glycosidic bond.


A secondary alcohol that is 3-methylpentane substituted at position 2 by a hydroxy group.


3-hydroxy steroid

Any hydroxy steroid carrying a hydroxy group at position 3.


FRUTICOSIDE A

A  3beta-hydroxy steroid that is 4-methylergosta-7,24(28)-dien-3-ol substituted by additional hydroxy groups at positions 2 and 21 (the 2alpha,3beta,4alpha,5alpha stereoisomer). It has been isolated from the roots of Breynia fruticosa and exhibits cytotoxic activity against human cancer cell lines.


A C21-steroid in which a pregnane skeleton carries a beta-hydroxy group at position 3, an alpha-hydroxy group at position 20 and a double bond between positions 4 and 5.


3alpha-hydroxy steroid

A 3-hydroxy steroid in which the 3-hydroxy substituent is in the alpha-position.


ISOFUCOSTEROL

A 3beta-sterol consisting of stigmastan-3beta-ol with double bonds at positions 5 and 24(28). The double bond at postion 24(28) adopts a Z-configuration.


ergostane sterol

Any sterol based on an ergostane skeleton and its derivatives.


A cholestanoid that is 5alpha-cholest-7-ene substituted by a beta-hydroxy group at position 3 and two methyl groups at position 4.


A 3beta sterol that is 5alpha-androstane which is substituted by beta-hydroxy groups at positions 3 and 17 and by an alpha-hydroxy group at position 7.


Any sterol that contains a double bond between positions 7 and 8.


An oxysterol that is (24S,25)-epoxycholesterol bearing a hydroxy substituent at the 7alpha-position.


A steroid glucosiduronic that is 5alpha-androstane-3alpha,17beta-diol carrying a glucosiduronic acid residue at position 17.


A 3-hydroxy steroid that is estra-1,3,5(10)-triene substituted by hydroxy groups at positions 3 and 16.


A 3-hydroxy steroid that is obtained by formal dehydrogenation across positions 7 and 8 of 17beta-estradiol.


A sterol that is cholestanol in which the hydrogen at the 6alpha position has been replaced by a hydroxy group.


An oxaspiro compound that is(5beta,25R)-spirostan substituted by a beta-hydroxy group at position 3.


BUFALIN

A 14beta-hydroxy steroid that is bufan-20,22-dienolide having hydroxy substituents at the 5beta- and 14beta-positions. It has been isolated from the skin of the toad Bufo bufo.


A steroid glucosiduronic acid that is 5alpha-androstane-3beta,17beta-diol having a single beta-D-glucuronic acid residue attached at position 17.


An oxysterol that is cholesterol which is substituted by hydroxy groups at positions 24S and 25.


A brassinosteroid that is castasterone in which the oxo group at position 6 has been converted to a hydroxy group (the 6alpha-stereoisomer).


cholestanol 7alpha,8alpha-epoxide

A cholestanoid that is lathosterol in which the double bond at position 7,8 has been oxidised to the corresponding epoxide (the 7alpha,8alpha stereoisomer).


A 3beta-sterol that is ergosterol having an additional double bond at position 14.


B-norcholesterol

A 3beta-hydroxy steroid that is cholesterol in which a methylene (CH2) group has been removed from the B-ring.


A cholestanoid obtained by formal condensation of the carboxy group of (25R)-3alpha,7alpha-dihydroxy-5beta-cholestan-26-oic acid with the amino group of taurine.


A 3beta-sterol that is 5alpha-cholest-8-en-3beta-ol carrying an additional carboxy substituent at position 4alpha.


esculeogenin A

A sapogenin that is spirosolane substituted by hydroxy groups at positions 3, 23 and 27 (the 3beta,5alpha,22alpha,23S,25S stereoisomer).


A 3beta-sterol that is 5alpha-cholest-8(14)-en-3beta-ol bearing an alpha-methyl substituent at position 4.


A 3beta-sterol that is 5alpha-ergosta-8,24(28)-diene substituted by geminal methyl groups at position 4 and a beta-hydroxy group at position 3. It has been isolated from the mycelia of Cordyceps sinensis.


A 3beta-sterol that consists of 4beta-methylzymosterol in which the 4alpha-hydrogen is replaced by a hydroxymethyl group.


convallasaponin A

A steroid saponin that consists of (1beta,3beta,5beta,25S)-spirostan-1,3,17-triol attached to a beta-D-glucopyranosyl-(1->2)-[beta-D-xylopyranosyl-(1->3)]-6-deoxy-beta-D-glucopyranosyl moiety at position 1 via a glycosidic linkage. It is isolated from the rhizomes of Convallaria majalis and exhibits significant cytotoxicity against human submandibular gland carcinoma (HSG) cells.


The 5alpha-stereoisomer of bufol.


A 3beta-sterol that is zymosterol which carries a hyroxymethyl group at position 4.


fecosterol

A 3beta-sterol having a 5alpha-ergostane skeleton with a methylidene group at C-24 and double bonds at the C-8 and C-24(28) positions.


A 3-hydroxy steroid that is solanid-5-ene substituted by a hydroxy group at position 3.


A 4-hydroxymethylzymosterol in which the hydroxymethyl group at position 4 has alpha-configuration.


A 3beta-sterol that is cholesterol substituted at position 7 by an amino group.


A steroid acid that has a carboxy group located at the 4alpha-position and a hydroxy substituent located at the 3beta-position.


ANDROSTANDIOL

The 5alpha-stereoisomer of androstane-3alpha,17beta-diol.


A 3beta-sterol that is cholesterol carrying an oxo group at position 22.


A 3beta sterol that is 5alpha-androstane which is substituted by beta-hydroxy groups at positions 3 and 17 and by an alpha-hydroxy group at position 6.


A 3beta-sterol that is methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol carrying an additional 4alpha-methyl substituent.


An oxysterol that is cholesterol which is substituted by hydroxy groups at positions 4beta and 24S.


A 3beta-hydroxy-4,4-dimethylsteroid that is that is cholestan-3beta-ol in which the hydrogens at position 4 have been replaced by methyl groups and a double bond has been introduced between positions 8 and 14.


ERGOSTEROL

A phytosterol consisting of ergostane having double bonds at the 5,6-, 7,8- and 22,23-positions as well as a 3beta-hydroxy group.


cycloartane sterol

Any sterol based on a cycloartane skeleton and its derivatives.


brassicasterol

An 3beta-sterol that is (22E)-ergosta-5,22-diene substituted by a hydroxy group at position 3beta. It is a phytosterol found in marine algae, fish, and rapeseed oil.


A 3beta-sterol consisting of an ergostane skeleton with double bonds at 7- and 22-positions.


A 3beta-hydroxy steroid that is teasterone lacking the oxo substituent at position 6.


bolandiol

A 3beta-hydroxy steroid that is estr-4-ene substituted by a beta-hydroxy group at positions 3 and 17. It is a synthetic anabolic steroid that is used as a dietary supplement by athletes to enhance performance.


A 7alpha,24-dihydroxycholesterol in which has R configuration at position 24.


6alpha,20xi-murideoxycholic acid

The 6alpha,20xi-stereoisomer of murideoxycholic acid.


A brassinosteroid that is brassinolide in which the hydroxy group at position 2 has been replaced by a hydrogen atom.


ANDROSTANEDIOL

An androstane-3,17-diol that is 5alpha-androstane substituted by beta-hydroxy groups at positions 3 and 17. It is a metabolite of dihydrotestosterone.


A 3beta-sterol that is  zymosterol substituted by a 4alpha-methyl group.


A 3beta-sterol that consists of 4beta-methylzymosterol in which the 4alpha-hydrogen is replaced by a carboxy group.


An oxysterol that is the 22S-hydroxy derivative of cholesterol.


clionasterol

A member of the class of phytosterols that is poriferast-5-ene carrying a beta-hydroxy substituent at position 3.


A phytosterol consiting of ergostane having double bonds at the 5,6- and 7,8-positions as well as a 3beta-hydroxy group.


dehydroergosterol

A phytosterol consiting of ergostane having double bonds at the 5,6-, 7,8- 9,11- and 22,23-positions as well as a 3beta-hydroxy group.


A 3beta-sterol having double bonds in the 5-, 7- and 22-positions and a methylene group at position 24.


An oxysterol that is cholesterol which is substituted by hydroxy groups at positions 7alpha and 22R.


estriol 16-O-(beta-D-glucuronide)

A steroid glucosiduronic acid that is estriol in which the phenolic hydrogen has been replaced by a beta-D-glucuronyl residue.


DIHYDRODIGOXIGENIN

A hydroxy steroid that is the 20,22-dihydro derivative of digoxigenin, consisting of 5beta-cardanolide with hydroxy groups at the 3beta-, 12beta- and 14beta-positions.


A steroid acid that is 3beta-hydroxy-4alpha-methyl-5alpha-cholesta-8,24-diene in which the hydrogen at the 4beta position has been replaced by a carboxy group.


brassinolide 23-O-alpha-D-glucoside

A brassinosteroid that is brassinolide carrying an alpha-D-glucosyl residue at position O-23.


A cholestanoid that is cholest-6-ene substituted by a beta-hydroxy group at position 3 and a peroxy group between positions 5 and 8 (the 5alpha,8alpha stereoisomer). Isolated from the sea urchin Diadema setosum, it exhibits cytotoxicity against variuos cancer cell lines.


stigmastane sterol

Any sterol based on a stigmastane skeleton.


A 3beta-hydroxy-Delta(5)-steroid with an unknown acyl group attached at position 25.


crinosterol

A 3beta-sterol that is campesterol in which position 22 has been dehydrogenated to introduce a double bond. It is a phytosterol found in marine algae, mussels, crinoids, mites and plants.


sterol

Any 3-hydroxy steroid whose skeleton is closely related to cholestan-3-ol (additional carbon atoms may be present in the side chain).


A 3-hydroxy steroid that is obtained by formal dehydrogenation across positions 6 and 7 of 17beta-estradiol.


A 3-hydroxy steroid that is (22E)-19-norcholesta-1,3,5(10),22-tetraene substituted by a hydroxy group at position 3.It is isolated from the Hainan soft coral Dendronephthya studeri.


A hydroxy steroid that consists of 5beta-cardanolide having a double bond at the 20(22)-position as well as hydroxy groups at the 3alpha,- 12beta- and 14beta-positions.


A stigmastane sterol that is sitosterol substituted by a hydroxy group at position 22S.


A 3-hydroxy steroid that is 24,26-cyclo-19-norcholesta-1,3,5(10),22-tetraene substituted by a hydroxy group at position 3. It is isolated from the Hainan soft coral Dendronephthya studeri.


A steroid glucosiduronic acid that is 2-hydroxy-17beta-estradiol having a single beta-D-glucuronic acid residue attached at position 2.


pregnane sterol

Any sterol based on a pregnane skeleton and its derivatives.


The 5beta-stereoisomer of bufol.


A 3beta-sterol having a 5alpha-ergostane skeleton with double bonds at C-6, C-9(11), C-22 and C-25 and a peroxy group between positions 5 and 8. An antineoplastic agent isolated from Okinawan sponge of the genus Axinyssa.


A 3alpha-hydroxy steroid that is androst-5-ene carrying three additional hydroxy groups at positions 3alpha, 16beta and 17beta.


androstane sterol

Any sterol based on a androstane skeleton and its derivatives.


lanostane sterol

Any sterol based on a lanostane skeleton and its derivatives.


An oxysterol that is cholesterol which is substituted by hydroxy groups at positions 24S and 27 and has S-configuration at position 25.


A 3beta-hydroxy steroid that is  sitosterol substituted by an additional alpha-hydroxy group at position 7. It has been isolated from the roots of Breynia fruticosa.


Any 3beta-hydroxy steroid which is substituted by two methyl groups at position 4.


A 3beta-sterol that is 5alpha-cholest-8-en-3beta-ol carrying carboxy and methyl substituents at position 4.


A 3-hydroxy steroid that is obtained by formal dehydration at the 17-position of estradiol.


The 3-alpha-hydroxy epimer of 6-deoxocathasterone.


A brassinosteroid that is campesterol bearing an additional 22S-hydroxy substituent.


oleandrigenin

A steroid ester that is the 16-acetyl derivative of gitoxigenin.


A steroid glucosiduronic acid that is 4-hydroxy-17beta-estradiol having a single beta-D-glucuronic acid residue attached at position 4.


A 17beta-hydroxy steroid, being 17beta-estradiol methoxylated at C-2.


sitosterol

A member of the class of phytosterols that is stigmast-5-ene substituted by a beta-hydroxy group at position 3.


Typhasterol in which the oxygen atom of the keto group has been substituted by two hydrogen atoms. A member of a biosynthetic pathway to castasterone, it has been isolated from the primary roots of maize.


A 3beta-sterol that is 5alpha-cholestane-3beta-ol having double bonds at the 8,9- and 14,15- positions.


An oxysterol that is cholesterol substituted by a hydroxy group at position 20.


A 3beta-hydroxy steroid that is beta-hydroxyandrost-5-ene carrying two additional hydroxy groups at positions 7alpha and 17beta.


A member of the class of phytosterols that is coprostanol carrying an additional ethyl substituent at position 24.


A 3alpha-hydroxy steroid that is castasterone which is lacking the oxo substituent at position 6.


A cholestanoid that zymosterol in which the two methyl groups at positions 26 and 27 have been replaced by a  cyclopropane ring.


Any 3beta-hydroxy-steroid that contains a double bond between positions 5 and 6.


A 3-hydroxy steroid that is (22E,24S)-24-methyl-19-norcholesta-1,3,5(10),22-tetraene substituted by a hydroxy group at position 3. It is isolated from Hainan soft coral Dendronephthya studeri.


24(S), 25-epoxycholesterol

A 3beta-hydroxy-Delta(5)-steroid that is desmosterol in which the double bond at position 24-25 has been oxidised to the corresponding epoxide (the 24S diastereoisomer). It is an oxysterol agonist of the liver X receptor.


A 3-hydroxy steroid resulting from deoxygenation at position 17 of estradiol or estrone.


A 7alpha,26-dihydroxycholesterol that has R configuration at position 25.


A 3beta-sterol that is 5alpha-cholest-8-en-3beta-ol carrying an additional methyl substituent at position 4alpha.


estradiol

A 3-hydroxy steroid that is estra-1,3,5(10)-triene substituted by hydroxy groups at positions 3 and 17.


A 3beta-sterol that is 5alpha-cholest-8-en-3beta-ol carrying hydroxymethyl and methyl substituents at position 4.


An oxysterol that is cholesterol carrying two additional hydroxy groups at the 4beta and 7alpha positions.


A 3beta-sterol that is 5alpha-stigmasta-7,24(28)-dien-3beta-ol which is substituted at the 4alpha position by a hydroxymethyl group and in which the 24(28) double bond has Z configuration.


A cholestanoid that is (5alpha)-cholestane substituted by a beta-hydroxy group at position 3.


3beta-hydroxy steroid

A 3-hydroxy steroid in which the 3-hydroxy substituent is in the  beta-position.


Any sterol containing two double bonds between positions 5-6 and 7-8.


estrane sterol

Any sterol based on an estrane skeleton and its derivatives.


dihydrodigitoxin

A cardanolide glycoside that is the 20,22-dihydro derivative of digitoxin.


omega-hydroxyfinasteride

A metabolite of finasteride.


A 3-hydroxy steroid that is (22E)-19,24-dinorcholesta-1,3,5(10),22-tetraene substituted by a hydroxy group at position 3. It is isolated from the Hainan soft coral Dendronephthya studeri.


A 3beta-sterol that is 24-methylidenelophenol in which the methyl group at position 4 has been oxidised to the corresponding hydroxymethyl group.


ERGOSTEROL PEROXIDE

An ergostanoid that is ergosta-6,22-dien-3-ol with a peroxy group between positions 5 and 8 (the 3beta,5alpha,8alpha,22E stereoisomer). Isolated from Ganoderma lucidum and Cordyceps sinensis, it exhibits antimycobacterial, trypanocidal and antineoplastic activities.


The 7-oxime of dehydroepiandrosterone, substituted on the oxime oxygen by a carboxymethyl group.


A  3-hydroxy steroid that is 19-norcholesta-1,3,5(10)-triene substituted by a hydroxy group at position 3. It is isolated from Hainan soft coral Dendronephthya studeri.


A cholestanoid that is cholestanol substituted by a hydroxy group at position 24S.


leucisterol

A member of the class of phytosterols that is stigmasta-5,22-diene substituted by hydroxy groups at positions 3 and 20 (the 3beta,22E stereoisomer). Isolated from the whole plants of Leucas urticifolia, it exhibits cholinesterase inhibitory activity.


FUCOSTEROL

A 3beta-sterol consisting of stigmastan-3beta-ol with double bonds at positions 5 and 24(28).


STIGMASTEROL

A 3beta-sterol that consists of 3beta-hydroxystigmastane having double bonds at the 5,6- and 22,23-positions.


An oxysterol that is cholesterol which is substituted by hydroxy groups at positions 24S and 26.


androstenediol

A 3beta-hydroxy-Delta(5)-steroid that is 3beta-hydroxyandrost-5-ene carrying an additional hydroxy group at position 17beta.


TOMATIDINE

A 3beta-hydroxy steroid resulting from the substitution of the 3beta-hydrogen of tomatidane by a hydroxy group.


DIGITOXIGENIN

A 5beta-cardenolide that is 5beta-cardanolide with hydroxy substituents at the 3beta- and 14beta-positions and double bond unsaturation at C(20)-C(22).


An estradiol that is estra-1,3,5(10)-triene substituted by hydroxy groups at positions 3 and 17 (the 17alpha stereoisomer).


A sterol in which the hydroxy group at position 3 has beta- configuration.


A brassinosteroid that is brassinolide carrying an additional hydroxy substituent at position 26.


A steroid glucosiduronic acid that consists of 17beta-estradiol having a beta-glucuronyl residue attached at position 17 via a glycosidic linkage.


fungisterol

An ergostanoid that is 5alpha-ergost-7-ene substituted by a beta-hydroxy group at position 3. It has been isolated from the mycelia of Cordyceps sinensis.


A 3beta-sterol consisting of an ergostane skeleton with double bonds at positions 8(9) and 22.


A 3beta-sterol having the structure of campestanol with a hydroxy group at the 6alpha-position.


pennogenin

An oxaspiro compound that is spirost-5-en substituted by hydroxy groups at positions 3 and 17 (3beta,25R stereoisomer).


COPROSTANOL

A member of the class of phytosterols that is 5beta-cholestane carrying a hydroxy substituent at the 3beta-position.


MUROCHOLIC ACID

A 3alpha-hydroxy steroid that is cholan-24-oic acid substituted by hydroxy groups at positions 3 and 6.


A 3beta-hydroxy steroid that is androst-5-en-3beta-ol in which the 17beta-hydrogen has been replaced by a 1,3-dihydroxy-3,3-bis(trifluoromethyl)propyl group. NCS172285 (also known as acts as NSC12) has been used as an extracellular fibroblast growth factor (FGF) trap with implications in cancer therapy. The stereochemistry shown is that of the most active stereoisomer, as determined by Mattia Anselmi (PhD thesis, University of Parma, 2015).


An oxysterol that is cholesterol substituted at position 26 by a hydroxy group.


halosterol B

A 3beta-hydroxy steroid that is (3beta)-stigmasta-4,6-diene-3-ol with an additional hydroxy group at position 22 (the 22R stereoisomer). Isolated from the whole plants of Haloxylon recurvum, it exhibits chymotrypsin inhibitory activity.


A 3beta-sterol that is 5alpha-cholest-8-en-3beta-ol carrying an additional hydroxymethyl substituent at position 4alpha.


A 17beta-hydroxy steroid that is 17beta-estradiol in which the hydrogen at position 4 has been replaced by a methoxy group.


oxysterol

An oxygenated derivative of cholesterol


A  3-hydroxy steroid that is (22E,24R)-24-methyl-19-norcholesta-1,3,5(10),22-tetraene substituted by a hydroxy group at position 3. It is isolated from Hainan soft coral Dendronephthya studeri.


A 3beta-sterol having the structure of cholesterol with a methylene group at C-24.


A 3beta-hydroxy-Delta(5)-steroid that is campesterol carrying two hydroxy groups at positions 22R and 23R.


gadoteridol

A non-ionic gadolinium chelate having a macrocyclic tetraamine framework. It is used as a paramagnetic contrast agent in magnetic resonance imaging (MRI).


gadoteric acid

A gadolinium coordination entity consisting of DOTA in which the four amino groups are bound to a central gadolinium atom. It is used (as its meglumine salt) in magnetic resonance imaging (MRI) in brain (intracranial), spine and associated tissues of patients ages 2 years and older, to detect and visualise areas with disruption of the blood brain barrier and/or abnormal vascularity of the central nervous system.


gadodiamide

The hydrate of gadodiamide.


gadoterate meglumine

An organoammonium salt obtained by reaction of gadoteric acid with one equivalent of 1-deoxy-1-(methylamino)-D-glucitol (meglumine). It is used in magnetic resonance imaging (MRI) in brain (intracranial), spine and associated tissues of patients ages 2 years and older, to detect and visualise areas with disruption of the blood brain barrier and/or abnormal vascularity of the central nervous system.


gadodiamide

A non-ionic gadolinium chelate having a macrocyclic triamine framework. It is used as a paramagnetic contrast agent in magnetic resonance imaging (MRI).


gadobutrol

A gadolinium coordination entity consisting of a central Gd(III) atom bound to a macrocyclic tetraamine framework. It is used as a paramagnetic contrast agent in magnetic resonance imaging (MRI).


SODIUM NITRATE

The inorganic nitrate salt of sodium.


Merosterolic acid B

Meroterpenoid from Scytonema sp. cyanobacteria mutant


A polyaniline polymer, composed of poly(2-methoxyaniline-5-sulfonic acid) macromolecules.


A sulfoglycosphingolipid that is sphingosine substituted on O-1 by a 3-O-sulfo-beta-D-galactosyl group; sulfatide in which one acyl chain has been removed by ozonolysis.


An alpha-D-Glcp-(1->3)-D-Galp in which the carbon bearing the anomeric hydroxy group has alpha configuration.


alpha-glucoside

A glucoside in which the anomeric carbon of the glycosidic bond is in an alpha configuration


A disaccaride that is alpha-D-galactopyranose in which the hydroxy group at position 6 has been converted into the corresponding alpha-D-glucopyranoside.


A synthetic alpha-D-glucoside that is a branched decasaccharide derivative consisting of alpha-L-rhamnosyl, N-acetyl-beta-D-glucosaminyl and alpha-D-glucosyl residues linked sequentially (1->3) and (1->4), to the alpha-D-glucosyl residue at the reducing end are also linked alpha-L-rhamnosyl and beta-D-glucosyl residues via (1->3) and (1->6) linkages respectively. An aminoethyl linker from the reducing-end Glc residue allows for efficient conjugation to a carrier protein.


NEAMINE

2-Deoxy-D-streptamine glycosylated at the 4-oxygen with a 6-amino-alpha-D-glucosaminyl group.


2-naphthyl alpha-D-glucoside

An alpha-D-glucoside that is alpha-D-glucopyranose in which the anomeric hydroxy hydrogen is replaced by a 2-naphthyl group.


An alpha-D-glucoside that is the 5-aminopentyl glycoside of a tetrasaccharide consisting of alpha-D-galactosyl, beta-D-glucuronosyl, beta-D-glucosyl and alpha-D-glucosyl residues linked sequentially (1->4).


A glucosylglycerol consisting of an alpha-D-glucosyl residue attached at position 2 of glycerol via a glycosidic bond.


A disaccharide that is D-galactopyranose in which the hydroxy group at position 3 has been converted into the corresponding alpha-D-glucopyranosyl derivative.


A trisaccharide that is D-galactopyranose in which the hydroxy group at position 2 has been converted to the corresponding alpha-D-glucopyranoside, while that at position 1 has been converted into the corresponding beta-D-glucopyranoside.


An alpha-D-glucoside that is the 5-aminopentyl glycoside of a branched hexasaccharide consisting of beta-D-mannosyl, alpha-D-glucosyl, beta-D-glucosyl, beta-D-mannosyl and beta-D-glucosyl residues linked sequentially (1->4), (1->3), (1->4) and (1->4), to the mannosyl residue proximal to the reducing end of which has also linked (1->3) to it an alpha-D-glucuronosyl residue. The 5-aminopentyl group at the reducing end is a spacer to enable further conjugation to a carrier protein for immunological studies.


An alpha-D-glucoside that is the 5-aminopentyl glycoside of a branched tetrasaccharide consisting of beta-D-glucosyl, beta-D-mannosyl and beta-D-glucosyl residues linked sequentially (1->4), to the mannosyl residue of which has also linked (1->3) to it an alpha-D-glucuronosyl residue. The 5-aminopentyl group at the reducing end is a spacer to enable further conjugation to a carrier protein for immunological studies.


alpha,beta-trehalose

A trehalose in which one of the glucose residues has alpha-configuration at the anomeric carbon, while the other has alpha-configuration.


An alpha-D-Glcp-(1->3)-D-Galp in which the carbon bearing the anomeric hydroxy group has beta configuration.


An alpha-D-glucoside that is the 5-aminopentyl glycoside of a branched pentasaccharide consisting of alpha-D-glucosyl, beta-D-glucosyl, beta-D-mannosyl and beta-D-glucosyl residues linked sequentially (1->3), (1->4) and (1->4), to the mannosyl residue of which has also linked (1->3) to it an alpha-D-glucuronosyl residue. The 5-aminopentyl group at the reducing end is a spacer to enable further conjugation to a carrier protein for immunological studies.


A branched octasaccharide consisting of beta-D-glucosyl, beta-D-mannosyl, alpha-D-glucosyl, beta-D-glucosyl, beta-D-mannosyl and beta-D-glucosyl residues linked sequentially (1->4), (1->4), (1->3), (1->4) and (1->4), with both mannosyl residues also having linked (1->3) to them alpha-D-glucuronosyl residues.


alpha-L-glucoside

Any L-glucoside in which the anomeric centre has alpha-configuration.


octyl alpha-D-glucopyranoside

An alpha-D-glucoside in which the anomeric hydrogen of alpha-D-glucopyranose is substituted by an octyl group.


An alpha-D-glucoside deoxygenated at C-2 and C-6.


An alpha-D-glucoside that is the 5-aminopentyl glycoside of a branched octasaccharide consisting of beta-D-glucosyl, beta-D-mannosyl, alpha-D-glucosyl, beta-D-glucosyl, beta-D-mannosyl and beta-D-glucosyl residues linked sequentially (1->4), (1->4), (1->3), (1->4) and (1->4), with both mannosyl residues also having linked (1->3) to them alpha-D-glucuronosyl residues. The 5-aminopentyl group at the reducing end is a spacer to enable further conjugation to a carrier protein for immunological studies.


MALTITOL

An alpha-D-glucoside consisting of D-glucitol having an alpha-D-glucosyl residue attached at the 4-position. Used as a sugar substitute.


anabolic androgenic steroid

A steroid hormone related to the hormone testosterone. It increases protein synthesis within cells, which results in the buildup of cellular tissue (anabolism), especially in muscles. It also has androgenic and virilizing properties.


flagella connector

category: biolink:CellularComponent biolink:AnatomicalEntity biolink:PhysicalEssence biolink:OrganismalEntity biolink:SubjectOfInvestigation biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: A mobile transmembrane junction at the tip of the flagellum of some kinetoplastid species linking the tip of a new growing flagellum to an older flagellum.


name: 4-(4-methylphenyl)-2-[[oxo-(2-oxo-1-benzopyran-3-yl)methyl]amino]-3-thiophenecarboxylic acid ethyl ester


A sialopentaosylceramide having beta-D-GalNAc-(1->4)-[alpha-Neu5Ac-(2->3)]-beta-D-Gal-(1->4)-beta-D-GalNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc as the sialopentaosyl component.


name: A. baumannii strain 54149 exopolysaccharide

description: A polysaccharide derivative that is the exopolysaccharide of Acetobacter baumannii strain 54149, the repeat unit consisting of N-acetyl-D-galactosamine beta-1,3 linked with D-galactose as the backbone with the galactose carrying a beta-1,6 linked glucose branch. Most repeating units (~90%) are decorated with beta-2,6-linked pseudaminic acid on the branch (CHEBI:141605).


tiotropium bromide

An organic bromide salt having (1alpha,2beta,4beta,5alpha,7beta)-7-[(hydroxydi-2-thienylacetyl)oxy]-9,9-dimethyl-3-oxa-9-azoniatricyclo[3.3.1.0(2,4)]nonane as the counterion. Used (in the form of the hydrate) for maintenance treatment of airflow obstruction in patients with chronic obstructive pulmonary disease.


amorphous cellulose

A (1->4)-beta-D-glucan (cellulose) in amorphous form with a structure consisting of several hundred to over ten thousand D-glucose residues joined by beta(1->4) glycosidic linkages.


macromolecule

A macromolecule is a molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.


name: S. flexneri serotype 1a O-polysaccharide (O factor 9-positive)

description: A polysaccharide derivative comprised of a [2)-alpha-L-Rhap(III)-(1->2)-alpha-L-Rhap(II)-(1->3)-alpha-L-Rhap(I)-(1->3)-beta-D-GlcpNAc-(1->] tetrasaccharide repeat modified by the (1->4) linkage of an alpha-D-glucosyl group to the GlcNAc residue and by addition of an acetyl group to either O-3 or O-4 of many of the Rha(III) residues (65% to O-3; 25% to O-4). The structure provided is representative of that in Shigella flexneri serotype 1a and shows the most common repeating unit.


Major species at pH 7.3


poly(oxyethylene)-block-polystyrene

A diblock copolymer composed of adjacent blocks of poly(oxyethylene) and polystyrene.


lentinan

A 1,3 beta-glucan polysaccharide with beta-1,6 branching  isolated from the edible mushroom Lentinula edodes. It has a molecular weight of around 500,000 Da; the exact composition is unknown.


colanic acid

A polyanionic heteropolysaccharide containing a repeat unit with D-glucose, L-fucose, D-galactose, and D-glucuronic acid sugars that are non-stoichiometrically decorated with O-acetyl and pyruvate side-chains


poly(D-arginine) macromolecule

A macromolecule composed of repeating D-arginyl units joined via peptide linkages.


poly(carbazole-1,8-diyl) macromolecule

A macromolecule composed of repeating 1,8-linked carbazole units.


A mannan consisting of repeating branched pentamannoside units joined via alpha-(1->6)-linkages.


poly(sodium 4-styrenesulfonate)

A polymer composed of repeating sodium 4-ethylbenzenesulfonate units.


A glycosaminoglycan composed of a backbone of repeating beta-D-glucuronosyl-(1->4)-N-acetyl-alpha-D-glucosamine units joined by (1->4)-linkages. The capsular polysaccharide produced by the E. coli K5 strain.


A polysaccharide derivative that is the O-antigen polysaccharide from Klebsiella pneumoniae, the repeating unit of which consists of alternating disaccharides of beta-D-galactopyranosyl-(1->3)-alpha-D-galactopyranose and beta-D-galactofuranosyl-(1->3)-alpha-D-galactopyranose.


A polysaccharide derivative with a repeating unit consisting of beta-D-galactosyl, beta-D-rhamnoosyl and beta-D-glucosyl residues all linked (1->4), to the galactosyl residue of which is attached an N-acetyl-beta-D-galactosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl disaccharide unit via a (1->3) linkage, while to the rhamnosyl residue is linked (1->3) an alpha-D-galactosyl residue, with all repeating units being linked (1->4). Desialylated polysaccharide of Streptococcus suis serotype 1/2.


polyanethol sulfonic acid macromolecule

A vinyl polymer macromolecule composed of repeating polyanethol sulfonic acid units. For the sake of clarity, a representative structure is shown; there may also be some of the 3-sulfonated analogue present.


A dendrimer macromolecule consisting of a malonamide core, each N of which carries a 2-[bis(2-{[2-({2-[(2-{[6-(beta-D-glucopyranosyl-(1->3)-beta-D-glucopyranosyl-(1->3)-beta-D-glucopyranosyl-(1->3)-beta-D-glucopyranosyl-(1->3)-beta-D-glucopyranosyl-(1->3)-beta-D-glucopyranosyloxy)hexanoyl]amino}ethyl)amino]-3,4-dioxocyclobut-1-en-1-yl}amino)ethyl]amino}-2-oxoethyl)amino]ethyl branch and with a 2-(2-{2-[(prop-2-yn-1-yl)oxy]ethoxy}ethoxy)ethyl substituent at C-2.


poly(vinylidene)

A polymer composed of repeating -CR2-CR2- units.


A beta-D-glucan of more than 20 D-glucose residues joined by beta-(1->3) and beta-(1->6) glycosidic linkages.


poly(ethylene imine)

A polymer composed of repeating ethylamine units.


A macromolecule composed of repeating dimethylcarbamoylethylene units.


name: poly[9,9-bis((6'-N,N,N-trimethylammonium)hexyl)fluorenylene phenylene dibromide] macromolecule

description: A macromolecule composed of repeating trimethyl(6-{2-phenyl-9-[6-(trimethylazaniumyl)hexyl]-9H-fluoren-9-yl}hexyl)azanium dibromideyl}hexyl)azanium units.


A beta-D-glucan in which the glucose units are connected by (1->4) linkages.


brominated poly[d(GC)]

A single-stranded DNA polynucleotide consisting of a repeating unit of brominated deoxyguanosine and deoxycytidine residues, with all residues connected by 3'->5' phosphodiester linkages.  The sites of bromination are at C-8 of guanine and C-5 of cytosine, although not all these sites are brominated, with bromination at the guanine C-8 predominating.


A polysaccharide composed of a backbone of alpha-galactopyranosyl-(1->3)-galactofuranosyl repeating units that are joined to each other also via beta-(1->3)-linkages; corresponds to the repeating unit of the O-specific polysaccharide from Plesiomonas shigelloides strain CNCTC 78/79, although in this species the O-acetylation is incomplete.


poly(deoxyadenylic acid)

A polynucleotide comprised of 2'-deoxyadenosine units connected via 3'->5' phosphodiester linkages. It is sometimes attached to eukaryotic messenger RNA and stabilizes the molecule before transport from the nucleus into the cytoplasm.


glucuronoxylan

A xylan composed of a beta-(1->4)-linked D-xylose backbone substituted with glucuronic acid residues.


maltodextrin

A dextrin in which the D-glucose units are linked by alpha-(1->4) glycosidic bonds.


VSWKTWFPNLAV

A twelve-membered polypeptide comprising the sequence Val-Ser-Trp-Lys-Thr-Trp-Phe-Pro-Asn-Leu-Ala-Val.


QINTAKWWKTHF

A twelve-membered polypeptide comprising the sequence Gln-Ile-Asn-Thr-Ala-Lys-Trp-Trp-Lys-Thr-His-Phe.


polyacrylamide macromolecule

An acrylic macromolecule prepared from acrylamide or a derivative of acrylamide.


An O-polysaccharide consisting of repeating 1,3-linked 6-deoxy-2-O-methyl-alpha-L-talosyl-(1->3)-beta-D-glucosyl units; it forms the O-antigen repeat section of one of the lipopolysaccharides of Burkholderia pseudomallei and/or Burkholderia mallei, the etiologic agents of melioidosis and glanders, respectively.


poly(2,7-fluorene) macromolecule

A macromolecule composed of repeating substituted or unsubstituted fluorene units linked at the 2- and 7-positions.


polyethylene macromolecule

A macromolecule composed of ethane or substituted ethane units.


A polysaccharide composed of a backbone of linear trisaccharide repeating units that are joined to each other via alpha-(1->2)-linkages; corresponds to the O repeating unit of Salmonella serogroup E.


osmoregulated periplasmic glucan

A branched glucan of 5 to 40 glucosyl residues found in the Gram-negative bacterial envelope. Can be substituted by non-sugar moieties, such as phosphoglycerol, phosphoethanolamine, phosphocholine, acetyl, succinyl and methylmalonyl. Osmoregulated periplasmic glucans show distinct structural diversity in their glucose backbones depending on the species they are produced by.


GlyTouCan G57818FI

A polysaccharide that is GlyTouCan G22140GZ in which the 2-acetamido-beta-D-glucopyranosyl group bearing the anomeric hydroxy group has been glycosylated at position 6 by an alpha-L-fucosyl group. For the structure shown, one of the R1 atoms and one of the R2 atoms represents a ?-D-Gal-(1->?)-?-D-GlcNAc-(1->?)- group; the remaining R1 and R2 atoms are hydrogens.


nisin

A type-A lantibiotic containing 34 amino acid residues (including lanthionine (Lan), methyllanthionine (MeLan), didehydroalanine (Dha) and didehydroaminobutyric acid (Dhb)) and five thioether bridges. It is obtained by fermentation of the bacterium Lactococcus lactis and shows particular activity against Clostridium botulinum. It is used in the production of various processed foods to suppress Gram-positive spoilage and pathogenic bacteria and so extend shelf life.


nanofibrillar cellulose

A (1->4)-beta-D-glucan consisting of elementary cellulose fibrils or their bundles, whose diameter lies typically in the range of 20-40 nm, but may be as small as 3-10 nm. The fibrils can exceed 1 mum in length.


poly(4-vinylbenzoic acid)

A vinyl polymer macromolecule composed of repeating 4-ethylbenzoic acid units.


poly(vinyltriphenylamine)

A polymer composed of repeating 4-ethyl triphenylamine groups.


epidermin

A type A lantibiotic that is a tetracyclic 21-amino-acid peptide which contains meso-lanthionine, 3-methyllanthionine, and S-(2-aminovinyl)-D-cysteine. It is obtained from Staphylococcus epidermidis Tue 3298 and exhibits antibiotic activity against many Gram-positive bacteria.


A 5,10-methylenetetrahydrofolate polyglutamate macromolecule in which the stereocentre at position 6 on the tetrahydrofolyl moiety has R-configuration.


polyalkenylene macromolecule

A macromolecule containing exclusively alkenylene (alkene-alpha,omega-diyl) units. A polymer of the form [-CH=CH-(CH2)m-]n.


mastoparan-B

A member of the class of mastopyrans that is a 14-amino acid polypeptide comprising leucyl, lysyl, leucyl, lysyl, seryl, isoleucyl, valyl, seryl, tryptophyl, alanyl, lysyl, lysyl, valyl, and leucinamide residues coupled in sequence. It is the major active component of the venom of the hornet Vespa basalis and causes degranulation of mast cells. It exhibits antimicrobial activity against both Gram-positive and -negative bacteria as well as haemolytic activity on chicken, human and sheep erythrocytes.


mastoparan-D

A member of the class of mastopyrans that is a 14-amino acid polypeptide comprising isoleucyl, asparaginyl, leucyl, lysyl, alanyl, isoleucyl, alanyl, alanyl, phenylalanyl, alanyl, lysyl, lysyl, leucyl, and leucinamide residues coupled in sequence. It is the major active component of the venom of the hornet Vespa ducalis and causes degranulation of mast cells. It exhibits antimicrobial activity against both Gram-positive and -negative bacteria as well as haemolytic activity on chicken, human and sheep erythrocytes.


name: S. flexneri serotype 5a O-polysaccharide (O factor 9-negative)

description: A polysaccharide derivative comprised of a [2)-alpha-L-Rhap(III)-(1->2)-alpha-L-Rhap(II)-(1->3)-alpha-L-Rhap(I)-(1->3)-beta-D-GlcpNAc-(1->] tetrasaccharide repeat modified by the (1->3) linkage of an alpha-D-glucosyl group to the Rha(II) residue.


starch

The most important reserve polysaccharide found in plants. It is a glucan consisting of amylose and amylopectin.


oxidised poly(vinyl alcohol)

A homopolymer macromolecule obtained by oxidiation of poly(vinyl alcohol). For the sake of convenience, a representative structure of the repeating unit is depicted; the extent of oxidation is variable.


poly(acrylic acid) macromolecule

An acrylic macromolecule, composed of acrylic acid repeating units.


A vinyl polymer composed of repeating -CH2-CR- units where R is a 4-pyridyl group.


A mimotope of the pyruvate dehydrogenase E2 component (PDC-E2) comprising a 4-bromobenzoyl group linked to the lipoated PDC-E2 core dodecapeptide (DKATIGFEVQEE) at N-6 of lysine.


poly(aniline) macromolecule

A macromolecule composed of repeating imino-1,4-phenylene units.


A mimotope of the pyruvate dehydrogenase E2 component (PDC-E2) comprising a {3-[2-(trifluoromethyl)phenyl]propanoyl} group linked to the lipoated PDC-E2 core dodecapeptide (DKATIGFEVQEE) at N-6 of lysine.


poly(ethylethylene)

A polymer composed of repeating butane-1,2-diyl units.


O-polysaccharide

A repetitive glycan polysaccharide contained within a lipopolysaccharide (LPS). The O-antigen is attached to the core oligosaccharide, and comprises the outermost domain of the LPS molecule.


A polysaccharide composed of a backbone of linear trisaccharide repeating units consisting of alpha-L-rhamnose, alpha-D-galactose and alpha-D-mannose residues linked sequentially (1->3) and (1->2), the repeating units being joined to each other via alpha(1->2)-linkages; corresponds to the backbone of the O-antigen repeat unit of the O:12 antigen common to Salmonella serogroups A, B and D.


poly[(R)-lactic acid]

A polymer composed of repeating (R)-2-hydroxypropanoyl units.


poly(p-divinylbenzene) macromolecule

A macromolecule composed of repeating p-phenylenediethylene units.


A mimotope of the pyruvate dehydrogenase E2 component (PDC-E2) comprising an octanoyl group linked to the lipoated PDC-E2 core dodecapeptide (DKATIGFEVQEE) at N-6 of lysine.


A polysaccharide derivative composed of a backbone of repeating D-glucuronosyl-(1->4)-N-acetyl-D-glucosamine units joined by (1->4)-linkages.


name: E. coli 180/C3 O-specific polysaccharide

description: A polysaccharide-derived antigen composed of a backbone of linear tetrasaccharide-derivative repeating units that are joined to each other via alpha-(1->2)-linkages.


A branched beta-D-glucan that consists of a beta-1,3-linked nonaglucan backbone with a beta-1,3-glucotetraose branch at the 6-O-position of the nonaglucan central sugar unit.


Major species at pH 7.3.


name: P. mirabilis O24 O-specific polysaccharide

description: A polysaccharide-derived antigen composed of a backbone of branched tetrasaccharide-derivative repeating units that are joined to each other via beta-(1->3)-linkages.


3-O-acetylated rhamnogalacturonan I

A galacturonan derivative obtained by acetylation at position 3 of galacturonyl residues of rhamnogalacturonan I. A representative structure is shown.


galactan

Polysaccharides composed of galactose residues.


A macromolecule composed of repeating (2-methoxy-5-sulfo-1,4-phenylene)imino units.


FPAWFTKLYPRT

A twelve-membered polypeptide comprising the sequence Phe-Pro-Ala-Trp-Phe-Thr-Lys-Leu-Tyr-Pro-Arg-Thr.


A copolymer of beta-D-mannopyranosyl-(1->2)-beta-D-mannopyranosyl-(1->2)-alpha-D-mannopyranoside and copovidone and comprised of 2-({3,4-dioxo-2-[(2-{[3-(vinyloxy)propyl]sulfanyl}ethyl)amino]cyclobut-1-en-1-yl}amino)ethyl beta-D-mannopyranosyl-(1->2)-beta-D-mannopyranosyl-(1->2)-alpha-D-mannopyranoside, vinyl alcohol and N-vinyl-2-pyrrolidone units.


Brucella O-antigen

A diblock copolymer in which one block consists of tetrasaccharide components comprising N-formyl-alpha-D-perosamine residues linked sequentially (1->2), (1->3) and (1->2) [alpha-D-Rhap4NFo-(1->2)-alpha-D-Rhap4NFo-(1->3)-alpha-D-Rhap4NFo-(1->2)-alpha-D-Rhap4NFo], with the second block consisting of N-formyl-alpha-D-perosamine residues linked solely (1->2). The percentage of (1->3) linkages compared with (1->2) ranges from 1% to 20% in different Brucella biovars.


heteroglycan

A polysaccharide composed of two or more different types of monosaccharides,


copolymer macromolecule

A macromolecule derived from two or more species of monomer.


poly(vinyl acetate)

A polymer composed of repeating acetoxyethylene units.


heparin icosasaccharide

Any heparin oligosaccharide consisting of 20 glycosidically linked monosaccharide residues.


A mismatched double-stranded RNA with one strand being a polymer of inosinic acid, the other a polymer of cytidylic acid.


A twelve-membered oligopeptide comprising AcAsp, N(6)-[lipoyl]-Lys, Ala, Thr, Ile, Gly, Phe, Glu, Val, Gln, Glu and Glu residues joined in sequence.


poly(lactic acid) macromolecule

A macromolecule composed of repeating 2-hydroxypropanoyl units.


Jeffamine ED-2001

A diamine in which two primary amino groups are at either end of what is essentially a poly(ethylene glycol) (PEG)backbone, consisting of blocks of ethylene oxide and propylene oxide. In the diagram, m ~ 39,; (l + n) ~ 6. The compound is one of a series of related compounds commonly used to crystallise proteins.


A mimotope of the pyruvate dehydrogenase E2 component (PDC-E2) comprising a 3-(trifluoromethyl)benzoyl group linked to the lipoated PDC-E2 core dodecapeptide (DKATIGFEVQEE) at N-6 of lysine.


poly(ethyl methacrylate) macromolecule

An acrylic macromolecule composed of repeating ethyl methacrylate units.


rRNA containing N(3)-methyluridine

A ribonucleic acid that is ribosomal RNA (rRNA) in which one of the RNA bases is N(3)-methyluridine.


polyisocyanide macromolecule

A polymer macromolecule composed of repeating substituted or unsubstituted methanimine units.


GlyTouCan G39397SW

A polysaccharide that is GlyTouCan G57818FI in which the terminal galactosyl groups have each been glycosylated by an N-glycolylneuraminic acid group. For the structure shown, one of the R1 atoms and one of the R2 atoms represents a ?-Neu5Gc-(1->?)-?-D-Gal-(1->?)-?-D-GlcNAc-(1->?)- group; the remaining R1 and R2 atoms are hydrogens.


poly(2,5-thiophene) macromolecule

A macromolecule composed of repeating thiophene or substituted thiophene units linked at the 2-and 5-positions.


poly(amido amine)

A polymer composed of amino (-NH2) and amido  (-C(=O)NH-) units.


rRNA containing N(4)-methylcytosine

A ribonucleic acid that is ribosomal RNA (rRNA) in which one of the RNA bases is N(4)-methylcytosine.


A branched polysaccharide composed of a backbone of repeating alpha-D-rhamnosyl-(1->3)-alpha-D-rhamnosyl-(1->2)-[alpha-D-rhamnosyl-(1->3)]-alpha-D-rhamnosyl-(1->2)-alpha-D-rhamnosyl units, joined by (1->3)-linkages.


A ionic polymer obtained by global deprotonation of the phosphate OH groups of any RNA linked to an adenine ribonucleotide in 3'; major structure at pH 7.3.


A macromolecule composed of repeating 2-methylfuran units and terminated with a hydroxy group at the methylene end.


GlyTouCan G42358LZ

An amino polysaccharide that is alpha-D-Manp-(1->3)-[beta-D-Manp-(1->6)]-beta-D-Manp-(1->4)-beta-D-GlcpNAc-(1->4)-beta-D-GlcpNAc in which one hydroxy group in each of the terminal mannose moieties has been converted into the corresponding Neu5Ac-(1->?)-?-D-Gal-(1->?)-?-D-GlcNAc-(1->?)- glycoside. For the structure shown, one of the R1 atoms and one of the R2 atoms represents a Neu5Ac-(1->?)-?-D-Gal-(1->?)-?-D-GlcNAc-(1->?)- group; the remaining R1 and R2 aroms are hydrogens.


amyloid-beta polypeptide 40

A beta-amyloid that is a 40 amino acid polypeptide of sequence Asp Ala Glu Phe Arg His Asp Ser Gly Tyr Glu Val His His Gln Lys Leu Val Phe Phe Ala Glu Asp Val Gly Ser Asn Lys Gly Ala Ile Ile Gly Leu Met Val Gly Gly Val Val.


poly(isocyanide) macromolecule

A macromolecule composed of repeating methanimine units.


lichenin

A glucan that is a major polysaccharide component of Cetraria islandica (Iceland moss). It is composed of beta-D-glucopyranose units linked in a linear manner by (1->4) and  (1->3) glycosidic bonds.


name: P. mirabilis O11 O-specific polysaccharide

description: A polysaccharide derivative consisting of a repeating unit of beta-D-glucuronosyl, beta-D-galacturonosyl and N-acetyl-beta-D-glucosaminyl residues linked sequentially (1->3) and (1->3), to the glucuronosyl and N-acetylglucosaminyl residues of which are linked respectively (1->2) and (1->6) an N-acetyl-beta-D-glucosaminyl residue and an alpha-D-glucosyl residue, while the galacturonosyl residue forms an amide with L-threonine, the complete pentasaccharide repeating units all being linked (1->4). The O-polysaccharide of Proteus mirabilis O11.


An acrylate macromolecule composed of repeating 1-methyl-1-[(oxiran-2-ylmethoxy)carbonyl]ethylene units.


arabinogalactan

A polysaccharide composed of repeating units of arabinosylgalactose.


KGKGKGKGKGENPVVHFFYNIVTPRTP

A linear 27-membered polypeptide comprising the sequence Lys-Gly-Lys-Gly-Lys-Gly-Lys-Gly-Lys-Gly-Glu-Asn-Pro-Val-Val-His-Phe-Phe-Tyr-Asn-Ile-Val-Thr-Pro-Arg-Thr-Pro. Corresponds to the sequence of the myelin basic protein 83-99 (MBP83-99) immunodominant epitope with the lysyl residue at position 91 replaced by tyrosyl [MBP83-99(Y(91))] and with an (L-lysylglycyl)5 [(KG5)] linker attached to the glutamine(83) (E(83)) residue.


A branched amino decasaccharide consisting of a hexasaccharide chain of beta-D-galactose, N-acetyl-beta-D-glucosamine, alpha-D-mannose, beta-D-mannose, and two N-acetyl-beta-D-glucosamine residues linked sequentially (1->4), (1->2), (1->3), (1->4) and (1->4), to the beta-D-mannose residue of which is (1->6)-linked a beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->3)-alpha-D-mannosyl trisaccharide branch and to the reducing end N-acetyl-beta-D-glucosamine residue of which is (1->6)-linked an alpha-L-fucose residue.  When it is the N-glycan content of the tumour necrosis factor (TNF) alpha blocker adalimumab, the two terminal galactose residues may be either absent or alternatively the linkage to the GlcNAc residues may be (1->3), while the fucose residue may be absent.


A polymer composed of repeating cis-2-methylbut-2-ene units.


poly(L-arginine) macromolecule

A macromolecule composed of repeating L-arginyl units joined via peptide linkages.


hemicellulose

Hemicelluloses are polysaccharides in plant cell walls that have beta-(1->4)-linked backbones with an equatorial configuration. Hemicelluloses include xyloglucans, xylans, mannans and glucomannans, and beta-(1->3,1->4)-glucans.


nonyl phenoxypolyethoxylethanol

Poly(ether) macoromolecule comprising a branched nonyl group bonded to one of the ring positions in 2-[phenoxypoly(ethoxy)]ethanol. A commericially available detergent, it is used to help crystallise proteins and extract the cytoplasmic contents of cellular culture.


polynaphthalene macromolecule

A macromolecule composed of repeating substituted or unsubstituted naphthalene units.


mastoparan-M

A member of the class of mastopyrans that is a 14-amino acid polypeptide comprising isoleucyl, asparaginyl, leucyl, lysyl, alanyl, isoleucyl, alanyl, alanyl, leucyl, alanyl, lysyl, lysyl, leucyl, and leucinamide residues coupled in sequence. It is the major active component of the venom of the hornet Vespa mandarinia and causes degranulation of mast cells. It exhibits antimicrobial activity against both Gram-positive and -negative bacteria as well as haemolytic activity on chicken, human and sheep erythrocytes.


An acrylic macromolecule, arising from poymerisation of N-isopropylamide.


heparosan L-iduronic acid

A heparan composed of a backbone of repeating alpha-L-iduronosyl-(1->4)-alpha-D-glucosamine units joined by (1->4)-linkages.


triacetylcellulose

A (1->4)-beta-D-glucan compound formed by total acetylation of cellulose.


A polysaccharide derivative comprising a trisaccharide repeating unit consisting of 2-acetamido-4-amino-2,4-dideoxy-alpha-D-fucose and two alpha-D-galacturonic acid residues linked sequentially (1->4) and (1->3) and with the trisaccharide repeats themselves being linked (1->3); corresponds to the serotype 1 capsular polysaccharide (CPS) of Streptococcus pneumoniae.


poly(guanylic acid)

A polynucleotide comprised of guanosine units connected via 3'->5' phosphodiester linkages.


mastoparan-AF

A member of the class of mastopyrans that is a 14-amino acid polypeptide comprising isoleucyl, asparaginyl, leucyl, lysyl, alanyl, isoleucyl, alanyl, alanyl, leucyl, alanyl, lysyl, lysyl, leucyl, and phenylalninamide residues coupled in sequence. It is the major active component of the venom of the hornet Vespa affinis and causes degranulation of mast cells. It exhibits antimicrobial activity against both Gram-positive and -negative bacteria as well as haemolytic activity on chicken, human and sheep erythrocytes.


name: S. flexneri serotype 6 O-polysaccharide (O factor 9-positive)

description: A polysaccharide derivative comprised of a [2)-alpha-L-Rhap(III)-(1->2)-alpha-L-Rhap(II)-(1->3)-beta-D-GalpA-(1->3)-beta-D-GalpNAc-(1->] tetrasaccharide repeat modified by the addition of an acetyl group to either O-3 or O-4 of many of the Rha(III) residues (60% to O-3; 30% to O-4). The structure provided is representative of that in Shigella flexneri serotype 6 and shows the most common repeating unit.


arabinan derivative

A homopolysaccharide derivative which is formally derived from an arabinan.


name: Legionella pneumophila O-specific polysaccharide

description: A polysaccharide derivative that is the alpha-(2->4)-interlinked homopolymer of 5,7-diacetamido-8-O-acetyl-3,5,7,9-tetradeoxy-D-glycero-alpha-L-galacto-nonulosonic acid. It is the O-specific chain of the lipolysaccharide from Legionella pneumophila serogroup 1.


lixisenatide

A forty-four membered polypeptide consisting of L-His, Gly, L-Glu, Gly, L-Thr, L-Phe, L-Thr, L-Ser, L-Asp, L-Leu, L-Ser, L-Lys, L-Gln, L-Met, L-Glu, L-Glu, L-Glu, L-Ala, L-Val, L-Arg, L-Leu, L-Phe, L-Ile, L-Glu, L-Trp, L-Leu, L-Lys, L-Asn, Gly, Gly, LPro, L-Ser, L-Ser, Gly, L-Ala, L-Pro, L-Pro, L-Ser, L-Lys, L-Lys, L-Lys, L-Lys, L-Lys, and L-Lys-NH2 residues joined in sequence. Used as an adjunct to diet and exercise for the treatment of adults with type II diabetes.


A polysaccharide derivative with a repeating unit consisting of beta-D-galactosyl, beta-D-rhamnoosyl and beta-D-glucosyl residues all linked (1->4), to the galactosyl residue of which is attached a beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl disaccharide unit via a (1->3) linkage, while to the rhamnosyl residue is linked (1->3) an alpha-D-galactosyl residue, with all repeating units being linked (1->4). Desialylated capsular polysaccharide of Streptococcus suis serotype 2


A dendrimer macromolecule consisting of a malonamide core, each N of which carries a 2-(bis{2-[(2-aminoethyl)amino]-2-oxoethyl}amino)ethyl branch and with a 2-[2-(2-azidoethoxy)ethoxy]ethyl substituent at C-2.


A polysaccharide derivative composed of a backbone of beta-D-galactopyranuronosyl-(1->3)-2-acetamido-4-amino-2,4,6-trideoxy-alpha-D-glucopyranosyl-(1->4)-beta-D-galactopyranurosyl repeating units that are joined to each other via (1->3)-linkages.


A branched pentasaccharide that is alpha-D-Manp-(1->3)-[alpha-D-Manp-(1->6)]-beta-D-Manp-(1->4)-beta-D-GlcpNAc-(1->4)-D-GlcpNAc in which the anomeric configuration of the reducing-end GlcNAc residue is beta.


A mimotope of the pyruvate dehydrogenase E2 component (PDC-E2) comprising a {(2E)-3-[3-(trifluoromethyl)phenyl]prop-2-enoyl}- group linked to the lipoated PDC-E2 core dodecapeptide (DKATIGFEVQEE) at N-6 of lysine.


telechelic polymer

A polymer carrying two reactive end-groups.


alpha-aminoacyl-tRNA

Any ribonucleic acid that is transfer RNA in which one or more of the free OH groups carries an alpha-aminoacyl group.


statistical copolymer

A copolymer in which the sequential distribution of the monomeric units obeys known statistical laws.


C/D box small nucleolar RNA

A small nucleolar RNA that functions in the 2'-O-ribose methylation of target RNA's. C/D box snoRNAs contain two short conserved sequence motifs, C (RUGAUGA) and D (CUGA), located near the 5' and 3' ends of the snoRNA, respectively.


A polymer composed of repeating 1-ethynylnaphthalene units.


reuteran

A soluble alpha-D-glucan with mainly alpha(1->4) glycosidic linkages but with also significant amounts of alpha(1->6) and alpha(1->4,6) linkages.


A sulfated glycosaminoglycan composed of a backbone of repeating beta-D-glucuronosyl-(1->4)-N-sulfonyl-alpha-D-glucosamine units, variably O-sulfated at the 6-position of the glucosamine residues and joined by (1->4)-linkages. The structure provided is representative and shows the most common repeating unit


pernigraniline macromolecule

A polyaniline macromolecule composed of aniline units connected by imine bonds.


poly(dA,dC)

A DNA random copolymer in which the monomeric units are adenosine and cytidine residues connected via 3'->5' phosphodiester linkages.


gamma-poly(glutamic acid) macromolecule

A macromolecule composed of repeating 2-amino-5-oxopentanoic acid units.


mucilages A

polysaccharides containing hexose and pentose sugars and uronic acids, is secreted by root cells as the root grows through the soil


A branched polysaccharide composed of a backbone of repeating alpha-D-Rhap-(1->3)-[alpha-D-Fucp-(1->4)]-alpha-D-Rhap-(1->2)-alpha-D-Rhap units, joined by (1->3)-linkages as shown.


CID 91859537

A polysaccharide consisting of alpha-D-Glcp-(1->2)-alpha-D-Glcp-(1->3)-alpha-D-Glcp-(1->3)-alpha-D-Manp-(1->2)-beta-D-Manp-(1->2)-alpha-D-Manp-(1->3)-beta-D-Manp-(1->4)-beta-D-GlcpNAc-(1->4)-alpha-D-GlcpNAc in which the beta-D-Manp- residue attached to the beta-D-Glcp residue is glycosylated at position 6 by an alpha-D-mannopyranosyl group, which in turn is substituted at positions 3 and 6 by 2-O-alpha-D-mannopyranosyl-alpha-D-mannopyranosyl groups.


A polysaccharide derivative with a repeating unit consisting of beta-D-galactosyl, beta-D-galactosyl and beta-D-glucosyl residues linked sequentially (1->3) and (1->4), to the galactosyl residue at the non-reducing end of which is attached a beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl disaccharide unit via a (1->3) linkage, with all repeating units being linked (1->6). Desialylated capsular polysaccharide of Streptococcus suis serotype 14.


A polysaccharide derivative composed of a repeating disaccharide unit, consisting of 2,3-diacetamido-2,3-dideoxy-D-mannuronic acid and 2,3-diacetamido-2,3-dideoxy-L-guluronic acid in an alternating linear sequence, joined by (1->4)-glycosidic linkages.


A galactan consisting of more than twenty galactose residues joined by beta-(1->4)-glycosidic linkages


semaglutide

A polypeptide that contains a linear sequence of 31 amino acids joined together by peptide linkages. It is an agonist of glucagon-like peptide-1 receptors (GLP-1 AR) and used for the treatment of type 2 diabetes.


A macromolecule composed of repeating diethylcarbamoylethylene units.


poly(metallocene) macromolecule

A macromolecule containing metal-eta5-cyclopentadienyl linkages.


An acrylate macromolecule, composed of repeating 2-(2-methoxyethoxy)ethyl 2-methylpropanoate units.


KGKGKGKGKGENPVVHFFFNIVTPRTP

A linear 27-membered polypeptide comprising the sequence Lys-Gly-Lys-Gly-Lys-Gly-Lys-Gly-Lys-Gly-Glu-Asn-Pro-Val-Val-His-Phe-Phe-Phe-Asn-Ile-Val-Thr-Pro-Arg-Thr-Pro. Corresponds to the sequence of the myelin basic protein 83-99 (MBP83-99) immunodominant epitope with the lysyl residue at position 91 replaced by phenylalanyl [MBP83-99(F(91))] and with an (L-lysylglycyl)5 [(KG5)] linker attached to the glutamine(83) (E(83)) residue.


A polysaccharide derivative with a repeating unit consisting of beta-D-galactosyl, beta-D-galactosyl and beta-D-glucosyl residues linked sequentially (1->3) and (1->4), to the galactosyl residue at the non-reducing end of which is attached an N-acetyl-alpha-neuraminyl-(2->6)-N-acetyl-beta-D-galactosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl trisaccharide unit via a (1->3) linkage, with all repeating units being linked (1->6). Capsular polysaccharide of Streptococcus suis serotype 1.


glycol nucleic acid

Nucleic acid polymers where the residues have an acyclic three-carbon propylene glycol phosphodiester backbone.


chondroitin D-glucuronate

A mucopolysaccharide composed of repeating beta-D-glucopyranuronosyl-(1->3)-beta-D-N-acetylgalactosaminyl units.


polyaniline macromolecule

A macromolecule prepared from aniline or a substituted aniline.


A macromolecule composed of repeating (propylcarbamoyl)ethylene units.


name: fluorinated polyhedral oligomeric silsesquioxane

description: A polyhedral oligomeric silsesquioxane containing fluorinated R groups.


O-acetylated pectin

A galacturonan derivative obtained via O-acetylation of pectin to achieve about 1.6 mol of O-acetyl per mol of GalA, implying that approximately 60% of the GalA is diacetylated.


poly(1,8-carbazole) macromolecule

A macromolecule composed of repeating 1,8-linked substituted or unsubstituted carbazole units.


poly(styrene) nanoparticle

A nanoparticle composed of poly(styrene).


STAT3 inhibitor peptide

A linear eighteen-membered polypeptide comprising the sequence Pro-Tyr-(PO3H2)-Leu-Lys-Thr-Lys-Ala-Ala-Val-Leu-Leu-Pro-Val-Leu-Leu-Ala-Ala-Pro.


poly(ethene-1,2-diyl) macromolecule

A macromolecule composed of repeating ethene units.


A fructan in which the D-fructose building blocks are connected by beta-(2->1) linkages.


An O-polysaccharide consisting of repeating 1,3-linked 2-O-acetyl-6-deoxy-alpha-L-talosyl-(1->3)-beta-D-glucosyl units; it forms the O-antigen repeat section of one of the lipopolysaccharides of Burkholderia pseudomallei and/or Burkholderia mallei, the etiologic agents of melioidosis and glanders, respectively.


A macromolecule composed of repeating octadecyl isobutyrate groups.


A polysaccharide derivative comprising a tetrasaccharide repeating unit consisting of beta-D-glucose, beta-D-galactose, beta-D-glucuronic acid and beta-D-glucose residues all linked sequentially (1->4) and with the tetrasaccharide repeats themselves being linked (1->4); corresponds to the serotype 8 capsular polysaccharide (CPS) of Streptococcus pneumoniae.


A branched beta-D-glucan that consists of a beta-1,3-linked nonaglucan backbone with a beta-1,6-glucotetraose branch at the 6-O-position of the nonaglucan central sugar unit.


corticorelin

A corticotropin-releasing hormone from human/rat composed of Ser, Glu, Glu, Pro, Pro, Ile, Ser, Leu, Asp, Leu, Val, Phe, His, Leu, Leu, Arg, Glu, Val, Leu, Glu, Met, Ala, Arg, Ala, Glu, Gln, Leu, Ala, Gln, Gln, Ala, His, Ser, Asn, Arg, Lys, Leu, Met, Glu, Ile and Ile-NH2 residues joined in sequence.


A heparin hexadecasaccharide consisting of 4-deoxy-2-O-sulfo-alpha-L-threo-hex-4-enopyranuronosyl, 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranosyl, 2-O-sulfo-alpha-L-idopyranuronosyl, 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranosyl, 2-O-sulfo-alpha-L-idopyranuronosyl, 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranosyl, 2-O-sulfo-alpha-L-idopyranuronosyl, 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranosyl, 2-O-sulfo-alpha-L-idopyranuronosyl, 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranosyl, 2-O-sulfo-alpha-L-idopyranuronosyl, 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranosyl, alpha-L-idopyranuronosyl, 2-acetamido-2-deoxy-6-O-sulfo-alpha-D-glucopyranosyl, beta-D-glucopyranuronosyl, and 2-deoxy-3,6-di-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose units joined in sequence by (1->4) linkages. Sequence: DUA2S-[-GlcNS6S-IdoA2S-]5-GlcNS6S-IdoA-GlcNAc6S-GlcA-GlcNS3S6S.


rRNA containing 2'-O-methyluridine

A ribonucleic acid that is ribosomal RNA (rRNA) in which one of the RNA nucleotides is 2'-O-methyluridine 5'-monophosphate.


poly(methyl acrylate) macromolecule

An acrylate macromolecule composed of repeating methoxycarbonylethylene units.


poly(methylstyrene)

A polymer composed of repeating methyl substituted ethylbenzene units (the methyl group may be on either the chain or the benzene ring).


N. meningitidis group C polysaccharide

A polysaccharide derivative that is the group C polysaccharide of Neisseria meningitidis, consisting of alpha(2->9)-linked sialic acid units. The polysaccharide chains can be conjugated to a carrier protein (e.g. CRM197), tetanus toxoid, ovalbumin, Hel) at a single site on the polysaccharide reducing end, at both termini of the (difuntional) polysaccharide chain or randomly along the polysaccharide chain (cross-linked).


GlyTouCan G80920RR

A partially-defined glycan consisting of 9 hexosyl and 2 acetaminohexosyl groups (identities and connectivity unknown). Composition: Hex9 HexNAc2.


A polysaccharide that is a branched dodecasaccharide consisting of three repeating tetrasaccharide units; reported to be a possible epitope of the O-antigen polysaccharide in Salmonella.


A polysaccharide derivative composed of a backbone of linear hexasaccharide derivative repeating units consisting of alpha-D-GalNAcAN-(1->4)-alpha-DGalNAcAN-(1->3)-beta-D-QuiNAc-(1->2)-beta-QuiN4Fm-(1->4)-alpha-D-GalNAcAN-(1->4)-alpha-DGalNAcAN connected by beta-(1->4) linkages.


name: poly(L-isocyanolalanyl-L-alanine methyl ester) macromolecule

description: A macromolecule composed of repeating methyl (2S)-2-[(2S)-2-(methylideneamino)propanamido]propanoate units.


A polysaccharide derivative that is the K2 capsular polysaccharide from Klebsiella pneumoniae, the repeating unit of which consists of a linear trisaccharide of D-galactose,  D-mannose and D-glucose residues with a side group of a further D-glucose residue.


poly(alpha-methylstyrene)

A polymer composed of repeating isopropylbenzene units.


Peptide that acts as a mechanosensitive ion channel blocker.


poly(phosphazene) macromolecule

A macromolecule composed of repeating phosphazene (-PR2=N-) units.


poly(deoxycytidylic acid)

A polynucleotide comprised of 2'-deoxycytidine units connected via 3'->5' phosphodiester linkages.


mastoparan

A member of the class of mastopyrans that is a 14-amino acid polypeptide comprising isoleucyl, asparaginyl, leucyl, lysyl, alanyl, leucyl, alanyl, alanyl, leucyl, alanyl, lysyl, lysyl, isoleucyl, and leucinamide residues coupled in sequence. It is the major active component of the venom of the vespid wasp, Vespula lewisii and causes degranulation of mast cells.


poly(3,9-carbazole) macromolecule

A macromolecule composed of repeating 3,9-linked substituted or unsubstituted carbazole units.


A polysaccharide that is galactogen linked to a (1->6)-beta-D-galactosyl unit.


A macromolecule composed of repeating N-acryloxysuccinimide units.


A polynucleotide which has a phosphate group at the 5'-terminus.


polysilsesquioxane macromolecule

A macromolecule molecule with a silsesquioxane repeating unit.


A macromolecule composed of repeating ethylene terephthalate units.


poly(alpha-alkylene)

A polymer generated by polymerisation of an alpha-alkene (an alkene where the C=C starts at the alpha-carbon atom).


hydroxyethylcellulose

A polysaccharide derivative that is cellulose in which hydroxyethyl groups are bound to some of the hydroxyl groups of the glucopyranose monomers.


A sulfated glycosaminoglycan composed of a backbone of repeating beta-D-glucuronosyl-(1->4)-N-acetyl-alpha-D-glucosamine units, variably O-sulfated at the 6-position of the glucosamine residues and joined by (1->4)-linkages. The structure provided is representative and shows the most common repeating unit


heparin sodium

The organic sodium salt of heparin.


methyl cellulose

A (1->4)-beta-D-glucan compound formed by methylating cellulose through exposure to NaOH/CH3Cl.


ENPAVHFFKNIVTPRTP

A linear seventeen-membered polypeptide comprising the sequence Glu-Asn-Pro-Ala-Val-His-Phe-Phe-Lys-Asn-Ile-Val-Thr-Pro-Arg-Thr-Pro. Corresponds to the sequence of the myelin basic protein 83-99 (MBP83-99) immunodominant epitope with the valyl residue at position 86 replaced by alanyl [MBP83-99(A(86))].


reduced (1->4)-beta-D-mannan

A mannan derivative in which (1->4)-beta-D-mannan has been subjected to reduction across a proportion of its C(2)-C(3)bonds. A representative structure is shown.


succinoglucan

A polysaccharide derivative composed mainly of a glucan in which succinoyl groups are bound to some of the hydroxyl groups of the glucopyranose monomers. The polysaccharide fragment consists of beta-(1->3)-, beta-(1->4)- and beta-(1->6)-linked glucose residues together with a small proportion of beta-(1->3)-linked galactose residues.


A glucan derivative that is (1->4)-alpha-D-glucan in which the 6-position of the repeating unit has been phosphorylated.


homopolysaccharide derivative

A polysaccharide derivative that is a derivative of any homopolysaccharide.


Cellulose, microcrystalline

A (1->4)-beta-D-glucan (cellulose) in crystalline form with a structure consisting of several hundred to over ten thousand D-glucose residues joined by beta(1->4) glycosidic linkages.


sizofiran

An exopolysaccharide produced by the basidiomycete Schizophyllum commune, consisting of a 1,3-beta-D-glucan backbone with 1,6-beta-D-glucosyl side chains; a multipurpose compound applicable in many fields, including the food industry and pharmacy.


exopolysaccharide

A biomacromolecule composed of carbohydrate residues which is secreted by a microorganism into the surrounding environment.


PCM 2476 oligosaccharide

The eleven-membered core polysaccharide derivitive from Yokenella regensburgei strain PCM 2476.


A polysaccharide derivative composed of a backbone of repeating beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl that are joined via (1->6)-linkages between the glucosyl and N-acetylglucosaminyl residues.


KGKGKGKGKGENPVVHFFKNIVTPRTP

A linear 27-membered polypeptide comprising the sequence Lys-Gly-Lys-Gly-Lys-Gly-Lys-Gly-Lys-Gly-Glu-Asn-Pro-Val-Val-His-Phe-Phe-Lys-Asn-Ile-Val-Thr-Pro-Arg-Thr-Pro. Corresponds to the sequence of the myelin basic protein 83-99 (MBP83-99) immunodominant epitope with an (L-lysylglycyl)5 [(KG5)] linker attached to the glutamine(83) (E(83)) residue.


poly(phenylenevinylene) macromolecule

A macromolecule composed of alternating substitutued or unsubstituted phenylene and vinyl groups.


acrylic macromolecule

A homopolymer macromolecule prepared from acrylic acid or a derivative of acrylic acid.


rhamnogalacturonan II

A low molecular mass (5 - 10Kd) pectic polysaccharide with a backbone of at least eight 1,4-linked alpha-D-GalpA residues. Two structurally distinct disaccharides are attached to C-3 of the backbone and two structurally distinct oligosaccharides are attached to C-2 of the backbone. These are represented by R groups.


sodium alginate

A copolymer macromolecule composed of homopolymeric blocks of 1->4-linked homopolymeric blocks of 1->4-linked sodium beta-D-mannuronate and sodium alpha-L-guluronate residues, covalently linked together in different sequences or blocks. The sodium salt of alginic acid.


A macromolecule composed of repeating 2-(diethylamino)ethyl isobutyrate units.


rRNA containing N(7)-methylguanine

A ribonucleic acid that is ribosomal RNA (rRNA) in which one of the RNA bases is N(7)-methylguanine.


A macromolecule composed of repeating (methylimino)[6-(methylamino)borazine-2,4-diyl]units.


A mannan consisting of repeating branched nonamannoside units joined via alpha-(1->6)-linkages.


A polysaccharide derivative that consists of a backbone of alpha-D-glucosyl-(1->4)-5,7-diacetyl-alpha-D-neuraminosyl repeating units, joined together by glycosidic linkages between position 2 of the diacetylneuraminosyl residues and position 6 of the glucosyl residues. The depicted structure is representative and shows the repeating unit, which is variably O-acylated at the 7-position of the neuraminosyl residues.


A macromolecule composed of repeating 1-((2-ethylhexyl)oxy)-4-methoxy-2-vinylbenzene units.


paucimannose N-glycan

Any N-glycan derivative with general formula Man1-4Fuc0-1 GlcNAc2. Found in relatively large amounts in invertebrates and plants, they are formed by removal of the peripheral GlcNAc of GlcNAcMan3-4GlcNAc2 by a Golgi hexosaminidase. Pauscimannose has also been detected in vertebrates.


dermatan

A mucopolysaccharide consisting of repeating beta-(1->4)-linked L-iduronyl-(alpha1->3)-N-acetyl-D-galactosamine units.


poly(1,3-butadiene) macromolecule

A macromolecule composed of repeating but-2-ene-1,4-diyl units.


name: beta-2,6-Pse-linked A. baumannii strain 54149 exopolysaccharide

description: A polysaccharide derivative that is the beta-2,6-pseudaminic acid-linked exopolysaccharide of Acetobacter baumannii strain 54149, the repeat unit consisting of N-acetyl-D-galactosamine beta-1,3 linked with D-galactose as the backbone with a beta-pseudaminyl-(2->6)-glucose branch linked beta-1,6 to the galactose.The beta-2,6-linked pseudaminic acid residue is present on ~90% of the galactose residues.


name: P. aeruginosa immunotype 3 O-specific polysaccharide

description: An O-polysaccharide composed of a backbone of linear trisaccharide repeating units that are joined to each other via beta-(1->4)-linkages. An antigen, it is the O-specific side chain of Pseudomonas aeruginosa immunotype 3 lipopolysaccharide.


poly[d(GA)]

A single-stranded DNA polynucleotide consisting of a repeating unit of deoxyguanosine and 5-methyldeoxyadenosine residues, with all residues connected by 3'->5' phosphodiester linkages.


polybutadiene macromolecule

A macromolecule generated from the monomer 1,3-butadiene.


glycogen

A polydisperse, highly branched glucan composed of chains of D-glucopyranose residues in alpha(1->4) glycosidic linkage, joined together by alpha(1->6) glycosidic linkages. A small number of alpha(1->3) glycosidic linkages and some cumulative alpha(1->6) links also may occur. The branches in glycogen typically contain 8 to 12 glucose residues.


A polyester macromolecule composed of repeating 3-hydroxycarboxylic acid units.


A 39 amino acid porcine cathelicidin that is rich in proline and arginine residues. It plays a pivotal role in the innate immune defence of the pig against infections and exhibits antimicrobial and immunomodulatory activities.


GlyTouCan G97763ON

A polysaccharide containing four D-galactopyranosyl groups, three D-mannopyranosyl groups, six acetamido-D-glucopyranosyl groups and one N-acetylneuraminic acid group. Composition: Hex7 HexNAc6 NeuAc1.


A mannan consisting of repeating D-mannosyl units joined via alpha-(1->6)-linkages.


ALFADEX

A cycloamylose composed of six alpha-(1->4) linked D-glucopyranose units.


syndiotactic macromolecule

A macromolecule in which the substituents are located on alternate sides of the backbone


A polysaccharide derivative comprising a trisaccharide repeating unit consisting of 4,N-diacetyl-beta-D-mannosaminouronic acid, N-acetyl-alpha-L-fucosamine and N-acetyl-beta-D-fucosamine residues linked sequentially (1->3), with the trisaccharide repeats themselves also being linked (1->3); corresponds to the serotype 8 (CP8) capsular polysaccharide of Staphylococcus aureus.


capsular polysaccharide

A polysaccharide capsule that is found on the cell surface of a broad range of bacterial species and often involved in mediating direct interactions between the bacteria and its environment. Due to these interactions, capsular polysaccharides have been implicated as important virulence factors for many bacterial pathogens. The molecules are highly hydrated and composed of repeating single monosaccharide units which are joined together by glycosidic linkages. They can be homo- or heteropolymers and can be substituted  with organic molecules such as acetyl groups, or or inorganic molecules such as phosphate.


poly(o-divinylbenzene) macromolecule

A macromolecule composed of repeating o-phenylenediethylene units.


poly(fluorene-2,7-diyl) macromolecule

A macromolecule composed of repeating fluorene-2,7-diyl units.


A mimotope of the pyruvate dehydrogenase E2 component (PDC-E2) comprising a 4-(trifluoromethyl)benzoyl group linked to the lipoated PDC-E2 core dodecapeptide (DKATIGFEVQEE) at N-6 of lysine.


poly-ADP-D-ribose

A biomacromolecule that is composed of ADP-D-ribose units linked through glycosidic ribose-ribose 1''->2' bonds. Branching may also occur.


poly(glycerol phosphate) teichoic acid

One of the teichoic acids in the cell wall of Gram-positive bacteria.


A macromolecule composed of repeating 3-hexylthiophene units.


polycarbazole macromolecule

A macromolecule composed of linked carbazole units.


YIIKGVFWDPAC

A twelve-membered polypeptide comprising the sequence Tyr-Ile-Ile-Lys-Gly-Val-Phe-Trp-Asp-Pro-Ala-Cys. Corresponds to the P34165[22-33] fragment of mating hormone A-factor 1 from Saccharomyces cerevisiae (strain ATCC 204508/S288c).


teduglutide

A 33-membered polypeptide consisting of His, Gly, Asp, Gly, Ser, Phe, Ser, Asp, Glu, Met, Asn, Thr, Ile, Leu, Asp, Asn, Leu, Ala, Ala, Arg, Asp, Phe, Ile, Asn, Trp, Leu, Ile, Gln, Thr, Lys, Ile, Thr and Asp residues joined in sequence. A  glucagon-like peptide-2 receptor agonist used for the treatment of short-bowel syndrome.


A macromolecule composed of repeating substituted or unsubstituted indolo[3,2-b]carbazole units.


An alpha-D-glucan in which the glucose units are connected by (1->6) linkages.


A polysaccharide derivative with a pentasaccharide repeat unit consisting of alpha-D-glucosyl, 2-O-acetyl-alpha-L-rhamnosyl and N-acetyl-beta-D-glucosaminyl residues all linked (1->3), to the alpha-glucosyl residue of which are attached a beta-D-glucosyl residue and an alpha-L-rhamnosyl residue via (1->6) and (1->3) linkages respectively, with all repeat units being linked (1->4). The repeat unit corresponds to that of the native Escherichia coli serotype O25B O-antigen.


A beta-D-glucan consisting of a poly[(1->4)-beta-D-glucosyl] chain attached at position 4 of D-glucono-1,5-lactone via a glycosidic linkage.


tirzepatide

A 39-amino acid linear polypeptide which is conjugated to a C20 fatty diacid moiety via a linker connected to lysine-20. It is a dual glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1 agonist used for the management of type 2 diabetes mellitus.


polycarbonate macromolecule

A macromolecule with functional groups linked by carbonate (-O-(C=O)-O-) groups.


polyamine macromolecule

A macromolecule composed of units connected by imino (-NR-) linkages.


poly(vinyl butyral) macromolecule

A macromolecule composed of repeating (2-propyl-1,3-dioxane-4,6-diyl)methylene units.


zineb

A polymeric complex of zinc with the ethylene bis(dithiocarbamate) anionic ligand. Formerly used as an agricultural fungicide for the control of downy mildews and rusts, its use is no longer permitted in the US or the EU.


A macromolecule composed of repeating 1-[(2-hydroxypropyl)carbamoyl]-1-methylethylene units.


propineb

A polymeric complex of zinc with the propylene 1,2-bis(dithiocarbamate) anionic ligand. A fungicide, it is used to control a wide range of fungal diseases, including downy mildew, brown rot, black rot, red fire, leaf spot, and blight in crops such as grapes, tomatoes, potatoes, berries, citrus, rice and tea.


A 26-amino acid peptide with formula C129H230N36O29S.  It is a cell permeable inhibitor of NF-kappaB translocation.


heparosan D-glucuronic acid

A heparan composed of a backbone of repeating beta-D-glucuronosyl-(1->4)-alpha-D-glucosamine units joined by (1->4)-linkages.


mersacidin

A type-B lantibiotic containing 3-methyllanthionine and S-(2-aminovinyl)-3-methylcysteine residues and four intra-chain thioether bridges. It is obtained from Bacillus sp. HIL Y-85,54728 and is active in vivo against methicillin-resistant Staphylococcus aureus (MRSA).


A branched polysaccharide derivative composed of a backbone of repeating [beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->6)]-beta-D-Glc-(1->4)-[beta-D-Glc-(1->3)]-beta-D-Gal-(1->4)-beta-D-Glc units, joined by (1->4)-linkages as shown.


calcitonin (salmon)

A 32-membered heterodetic cyclic peptide comprising the sequence Cys-Ser-Asn-Leu-Ser-Thr-Cys-Val-Leu-Gly-Lys-Leu-Ser-Gln-Glu-Leu-His-Lys-Leu-Gln-Thr-Tyr-Pro-Arg-Thr-Asn-Thr-Gly-Ser-Gly-Thr-Pro-NH2 cyclised by a disulfide bridge between the two Cys residues at positions 1 and 7.


poly[d(TTC)]

A single-stranded DNA polynucleotide consisting of a repeating sequence of two thymidine residues and one deoxycytidine residue, with all residues connected by 3'->5' phosphodiester linkages.


Brucella sp. O-PS M-antigen

A polysaccharide-derived antigen composed of a backbone of penta-(4,6-dideoxy-4-formamido-D-mannopyranose) repeating units that are joined to each other via alpha-(1->2)-linkages.


poly(1,3-cyclopentylene vinylene)

A polymer composed of repeating 1,3-cyclopentylene vinylene units.


name: H. influenzae type B capsular polysaccharide

description: A polysaccharide derivative that is the capsular polysaccharide of Harmophilus influenzae type b, consisting of (5->3)-phosphodiester-linked beta-Dribofuranosyl-(1->1)-D-ribitol units. The whole can be conjugated to a carrier protein [e.g. CRM197, outer membrane protein complex (OMPC)] at a single site on the polysaccharide reducing end or randomly along the polysaccharide chain (cross-linked).  An example structure is shown in the diagram.


calpastatin peptide Ac 184-210

A 27-membered polypeptide comprising the sequence Ac-Asp-Pro-Met-Ser-Ser-Thr-Tyr-Ile-Glu-Glu-Leu-Gly-Lys-Arg-Glu-Val-Thr-Ile-Pro-Pro-Lys-Tyr-Arg-Glu-Leu-Leu-Ala-NH2. An acetylated synthetic peptide from human calpastatin that strongly inhibits both calpains I and II but not papain (a cysteine protease) or trypsin (a serine protease).


poly(3-ethoxythiophene) macromolecule

A macromolecule composed of repeating 3-ethoxythiophene units.


name: S. flexneri serotype 5b O-specific polysaccharide

description: A polysaccharide derivative antigen composed of a backbone of repeating alpha-D-Glc-(1->3)-alpha-L-Rha-(1->2)-[alpha-D-Glc-(1->3)]-alpha-L-Rha-(1->3)-alpha-L-Rha-(1->3)-beta-D-GlcNAc units that are connected via beta-(1->2)-linkages between the GlcNAc and the Rha residue adjacent to the first Glc.


A fructan compound consisting of repeating (2->6)-beta-linked fructofuranose units.


poly(p-dioxanone) macromolecule

A macromolecule composed of repeating 2-hydroxyethoxyacetyl units, obtained via ring-opening polymerisation of p-dioxanone.


A polypeptide consisting of the first 18 amino acids at the N-terminus of the Bacterial Elongation Factor Tu protein that is capable of eliciting an innate immunity response in plants.


A diblock copolymer composed of adjacent blocks of polystyrene and poly(N-isopropylacrylamide).


A macromolecule made up of nucleotide units and hydrolysable into certain pyrimidine or purine bases (usually adenine, cytosine, guanine, thymine, uracil), D-ribose or 2-deoxy-D-ribose and phosphoric acid with a phosphate group at the 3'-end.


poly[(S)-lactic acid]

A polymer composed of repeating (S)-2-hydroxypropanoyl units.


name: S. flexneri serotype Y O-polysaccharide (O factor 9-positive)

description: A polysaccharide derivative comprised of a [2)-alpha-L-Rhap(III)-(1->2)-alpha-L-Rhap(II)-(1->3)-alpha-L-Rhap(I)-(1->3)-beta-D-GlcpNAc-(1->] tetrasaccharide repeat modified by addition of acetyl groups to 40% of the O-6 positions of the GlcNAc residue and to either O-3 or O-4 of many of the Rha(III) residues (30% to O-3; 20% to O-4). The structure provided is representative of that in Shigella flexneri serotype Y and shows the most common repeating unit.


heparin dodecasaccharide

Any heparin oligosaccharide consisting of 12 glycosidically linked monosaccharide residues.


name: S. flexneri serotype 2a O-polysaccharide (O factor 9-positive)

description: A polysaccharide derivative comprised of a [2)-alpha-L-Rhap(III)-(1->2)-alpha-L-Rhap(II)-(1->3)-alpha-L-Rhap(I)-(1->3)-beta-D-GlcpNAc-(1->] tetrasaccharide repeat modified by the (1->4) linkage of an alpha-D-glucosyl group to the Rha(I) residue and by addition of acetyl groups to 60% of the O-6 positions of the GlcNAc residue  and to either O-3 or O-4 of many of the Rha(III) residues (60% to O-3; 25% to O-4). The structure provided is representative of that in Shigella flexneri serotype 2a and shows the most common repeating unit.


poly(galactose) macromolecule

A macromolecule composed of repeating 1,6-linked hexane-1,2,3,4,5,6-hexol units.


A galacturonan derivative that is a linear homopolymer of (1->4)-alpha-D-GalpANAc, variably O-acetylated at the 3-position.


A twelve-membered oligopeptide comprising AcAsp, Lys, Ala, Thr, Ile, Gly, Phe, Glu, Val, Gln, Glu and Glu residues joined in sequence.


ENPVVHFFFNIVTPRTP

A linear seventeen-membered polypeptide comprising the sequence Glu-Asn-Pro-Val-Val-His-Phe-Phe-Phe-Asn-Ile-Val-Thr-Pro-Arg-Thr-Pro. Corresponds to the sequence of the myelin basic protein 83-99 (MBP83-99) immunodominant epitope with the lysyl residue at position 91 replaced by phenylalanyl [MBP83-99(F(91))].


An  arabinan composed of arabinose units joined via (1->5) linkage.


A macromolecule composed of repeating 1-methyl-1-{[(1',3',3'-trimethyl-1',3'-dihydrospiro[chromene-2,2'-indol]-6-yl)oxy]carbonyl}ethylene units.


jeffamine diamine

Any one of a class of di- or tri-block copolymers with a structure consisting of a primary amino group attached to each end of a polyether backbone based on blocks of butylene oxide, propylene oxide or both propylene oxide and ethylene oxide. Molecular weights are typically of the order of 200-4000. The compounds are used in protein crystallisation.


A polysaccharide derivative with a repeating unit consisting of alpha-D-mannosyl, alpha-L-rhamnosyl (acetylated on either O-2 or -3) and alpha-D-galactosyl residues linked sequentially (1->4) and (1->3), to the mannosyl residue is linked (1->3) an alpha-abequosyl residue (partially acetylated on O-2), while to the galactosyl residue is linked (1->4) or (1->6) an alpha-D-glucosyl residue, with all repeating units being linked (1->2). O-polysaccharide repeat from Salmonella Typhimurium (serogroup B).


A macromolecule composed of repeating acetyliminoethylene units and terminated by a hydroxy group. Prepared via ring-opening polymerisation of 2-methyl-2-oxazoline.


A macromolecule composed of repeating 2,5-bis(cholestanoxy)-1,4-phenylenevinylene units.


random copolymer

A copolymer consisting of macromolecules in which the probability of finding a given monomeric unit at any given site in the chain is independent of the nature of the adjacent units.


poly(sulfide) macromolecule

A macromolecule containing sulfur-sulfur linkages in the backbone.


A polymer composed of repeating 1-(4-iodophenyl)ethylene units.


A macromolecule composed of repeating 2-methyl-2-propionamidopropane-1-sulfonic acid units.


An ionic macromolecule obtained by global deprotonation of the carboxy groups of 10-formyltetrahydrofolyl-(Glu)n. Major microspecies at pH 7.3


poly(diacetylene) macromolecule

Macromolecule composed of repeating substituted or unsubstituted but-1-en-3-yne units.


corticorelin ovine

A corticotropin-releasing hormone from sheep composed of Ser, Gln, Glu, Pro, Pro, Ile, Ser, Leu, Asp, Leu, Val, Phe, His, Leu, Leu, Arg, Glu, Val, Leu, Glu, Met, Thr, Lys, Ala, Asp, Gln, Leu, Ala, Gln, Gln, Ala, His, Ser, Asn, Arg, Lys, Leu, Leu, Asp, Ile and Ala-NH2 residues joined in sequence.


poly(2,9-carbazole) macromolecule

A macromolecule composed of repeating 2,9-linked substituted or unsubstituted carbazole units.


A branched polysaccharide composed of a backbone of repeating beta-L-rhamnosyl-(1->4)-beta-D-glucosyl-(1->3)-[alpha-D-glucuronosyl-(1->6)-alpha-D-glucosyl-(1->2)]-alpha-L-rhamnosyl-(1->3)-alpha-L-rhamnosyl units, joined by (1->3) linkages. The repeating unit is that of the Streptococcus pneumoniae serotype 2 capsular polysaccharide.


poly(deoxyguanylic acid)

A polynucleotide comprised of 2'-deoxyguanosine units connected via 3'->5' phosphodiester linkages.


A polysaccharide composed of an alpha-D-glucosyl residue joined to a [(2->6)-beta-D-fructosyl]n moiety by an alpha-(1->2) linkage.


apiogalacteronin

A pectic compound characterized by a backbone of alpha-(1->4)-linked D-galacturonic acid residues substituted with apiose and apiobiose (D-apiofuranosyl-beta-(1->3)-D-apiose) side chains via O-2 or O-3 links. These are represented by R groups in the structure.


dermaseptin s3(1-16)-NH2

A sixteen membered polypeptide consisting of Ala, Leu, Trp, Lys, Asn, Met, Leu, Lys, Gly, Ile, Gly, Lys, Leu, Ala, Gly and Lys-NH2 residues joined in sequence. A fragment of the amphibian skin peptide dermaseptin s3


poly(1,4-phenylene oxide) macromolecule

A macromolecule composed of repeating 1,4-oxyphenylene units.


single-stranded DNA polynucleotide

A polynucleotide consisting of deoxyribonucleotide residues connected by phosphodiester linkages.


alternating copolymer

A copolymer comprising two species of monomer distributed in an alternating sequence.


A polysaccharide derivative composed of a backbone of linear trisaccharide derivative repeating units that are joined to each other via beta-(1->4)-linkages; corresponds to the repeating unit of the O-polysaccharide from Pasteurella haemolytica serotypes 1, 6 and 9.


d3-PMMA macromolecule

A macromolecule composed of repeating methyl methacrylate units in which three of the hydrogen atoms on the methacrylate moiety have been replaced by deuterium atoms.


A (1->3)-beta-D-glucan consisting of 15 glucosyl residues linked in a linear sequence.


rhamnan

Any homopolysaccharide composed of rhamnose residues.


An O-polysaccharide consisting of repeating 1,3-linked 2,4-di-O-acetyl-6-deoxy-alpha-L-talosyl-(1->3)-beta-D-glucosyl units; it forms the O-antigen repeat section of one of the lipopolysaccharides of Burkholderia pseudomallei and/or Burkholderia mallei, the etiologic agents of melioidosis and glanders, respectively.


A polysaccharide derivative comprised of repeating sialyl residues, linked (2->9).


polyglycine macromolecule

A macromomecule composed of repeating substituted or unsubstituted glycine units connected via amide linkages.


A thirteen-membered polypeptide consisting of p-Glu, Arg, Pro, Arg, Leu, Ser, His, Lys, Gly, Pro, Met, Pro and Phe residues joined in sequence.


jeffamine monoamine

Any one of a class of diblock copolymers with a structure consisting of a primary amino group attached to the end of a polyether backbone based on blocks of propylene oxide and ethylene oxide. Molecular weights are typically of the order of 600-2000. The compounds are used in protein crystallisation.


polyester macromolecule

A macromolecule composed of units connected by carboxylic ester (-O-CO-) linkages.


name: P. mirabilis O43 O-specific polysaccharide

description: A polysaccharide-derived antigen composed of a backbone of linear tetrasaccharide-derivative repeating units that are joined to each other via alpha-(1->4)-linkages.


A polysaccharide derivative with a repeating unit consisting of beta-D-galactosyl, beta-D-galactosyl and beta-D-glucosyl residues linked sequentially (1->3) and (1->4), to the galactosyl residue at the non-reducing end of which is attached an N-acetyl-alpha-neuraminyl-(2->6)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl trisaccharide unit via a (1->3) linkage, with all repeating units being linked (1->6). Capsular polysaccharide of Streptococcus suis serotype 14.


name: N-(6-aminohexanoyl)-6-aminohexanoic acid zwitterion monomer

description: Conjugated acid of chebi:78395 This is an attempt to handle the fact that the free amino group should be charged but not the amido groups


dextran

A (1->6)-alpha-D-glucan which has extra branching consisting of (1->2), (1->3) or (1->4) linkages.


poly(n-hexyl isocyanate) macromolecule

A macromolecule composed of repeating N-hexylformamide units.


A beta-D-glucan consisting of [3)-beta-D-Glcp-(1->]15 in which the fifth and tenth glucosides from the reducing end are substituted at position 6 by beta-D-glucoside residues.


liraglutide

A lipopeptide that is an analogue of human GLP-1 in which the lysine residue at position 27 is replaced by arginine and a hexadecanoyl group attached to the remaining lysine via a glutamic acid spacer. Used as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.


poly(vinyl benzoate)

A polymer composed of repeating ethylbenzoate units.


poly(isobutylene)

A polymer composed of repeating 1,1-dimethylethylene units.


apiogalacturonan

A pectin polymer characterized by a backbone of alpha-(1-4)-linked D-galacturonic acid residues substituted with apiose and apiobiose (D-apiofuranosyl-beta-(1-3)-D-apiose) side chains via O-2 or O-3 links.


A polysaccharide composed of a backbone of alpha-galactopyranosyl-(1->3)-galactofuranosyl repeating units that are joined to each other via beta-(1->4)-linkages; corresponds to the repeating unit of the O-polysaccharide from Pasteurella haemolytica serotypes 4 and 10.


An acrylic macromolecule, composed of repeating trimethyl[2-(isobutanoyloxy)ethyl]azanium chloride units.


polyelectrolyte macromolecule

A macromolecule containing a group that will dissociate in aqueous solution, making it charged.


betadex

A cyclodextrin composed of seven alpha-(1->4) linked D-glucopyranose units.


poly(caprolactone) macromolecule

A homopolymer macromolecule, prepared from epsilon-caprolactone.


A polymer composed of repeating 5-hydroxypentanoyl units.


poly(glycine) macromolecule

A macromolecule composed of repeating glycine units connected via amide linkages.