name: Exocytosis of azurophil granule membrane proteins (Bos taurus)


name: Exocytosis of ficolin-rich granule membrane proteins (Sus scrofa)

category: biolink:MolecularActivity biolink:Occurrent biolink:OntologyClass biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent


name: Exocytosis of tertiary granule membrane proteins (Sus scrofa)


name: Exocytosis of tertiary granule lumen proteins (Sus scrofa)


name: Exocytosis of specific granule membrane proteins (Sus scrofa)


name: Exocytosis of specific granule lumen proteins (Sus scrofa)


name: Exocytosis of secretory granule membrane proteins (Sus scrofa)


name: Exocytosis of ficolin-rich granule lumen proteins (Sus scrofa)


name: Exocytosis of azurophil granule lumen proteins (Sus scrofa)


name: Exocytosis of secretory granule lumen proteins (Sus scrofa)


name: Exocytosis of azurophil granule membrane proteins (Sus scrofa)


name: Exocytosis of specific granule lumen proteins (Danio rerio)


name: Exocytosis of azurophil granule membrane proteins (Danio rerio)


name: Exocytosis of ficolin-rich granule membrane proteins (Danio rerio)


name: Exocytosis of secretory granule lumen proteins (Danio rerio)


name: Exocytosis of tertiary granule lumen proteins (Danio rerio)


name: Exocytosis of azurophil granule lumen proteins (Danio rerio)


name: Exocytosis of tertiary granule membrane proteins (Danio rerio)


name: Exocytosis of specific granule membrane proteins (Danio rerio)


name: Exocytosis of secretory granule membrane proteins (Danio rerio)


name: Exocytosis of ficolin-rich granule lumen proteins (Danio rerio)


name: Exocytosis of secretory granule lumen proteins (Xenopus tropicalis)


name: Exocytosis of ficolin-rich granule lumen proteins (Xenopus tropicalis)


name: Exocytosis of azurophil granule lumen proteins (Xenopus tropicalis)


name: Exocytosis of specific granule membrane proteins (Xenopus tropicalis)


name: Exocytosis of secretory granule membrane proteins (Xenopus tropicalis)


name: Exocytosis of specific granule lumen proteins (Xenopus tropicalis)


name: Exocytosis of ficolin-rich granule membrane proteins (Xenopus tropicalis)


name: Exocytosis of azurophil granule membrane proteins (Xenopus tropicalis)


name: Exocytosis of tertiary granule membrane proteins (Xenopus tropicalis)


name: Exocytosis of tertiary granule lumen proteins (Xenopus tropicalis)


name: Exocytosis of azurophil granule lumen proteins (Gallus gallus)


name: Exocytosis of ficolin-rich granule lumen proteins (Gallus gallus)


name: Exocytosis of tertiary granule lumen proteins (Gallus gallus)


name: Exocytosis of azurophil granule membrane proteins (Gallus gallus)


name: Exocytosis of tertiary granule membrane proteins (Gallus gallus)


name: Exocytosis of specific granule lumen proteins (Gallus gallus)


name: Exocytosis of specific granule membrane proteins (Gallus gallus)


name: Exocytosis of secretory granule lumen proteins (Gallus gallus)


name: Exocytosis of ficolin-rich granule membrane proteins (Gallus gallus)


name: Exocytosis of secretory granule membrane proteins (Gallus gallus)


name: Exocytosis of tertiary granule lumen proteins (Drosophila melanogaster)


name: Exocytosis of secretory granule membrane proteins (Drosophila melanogaster)


name: Exocytosis of specific granule membrane proteins (Drosophila melanogaster)


name: Exocytosis of azurophil granule membrane proteins (Drosophila melanogaster)


name: Exocytosis of ficolin-rich granule membrane proteins (Drosophila melanogaster)


name: Exocytosis of specific granule lumen proteins (Drosophila melanogaster)


name: Exocytosis of azurophil granule lumen proteins (Drosophila melanogaster)


name: Exocytosis of tertiary granule membrane proteins (Drosophila melanogaster)


name: Exocytosis of secretory granule lumen proteins (Drosophila melanogaster)


name: Exocytosis of ficolin-rich granule lumen proteins (Drosophila melanogaster)


name: Exocytosis of secretory granule membrane proteins (Caenorhabditis elegans)


name: Exocytosis of secretory granule lumen proteins (Caenorhabditis elegans)


name: Exocytosis of ficolin-rich granule membrane proteins (Caenorhabditis elegans)


name: Exocytosis of ficolin-rich granule lumen proteins (Caenorhabditis elegans)


name: Exocytosis of specific granule lumen proteins (Caenorhabditis elegans)


name: Exocytosis of tertiary granule membrane proteins (Caenorhabditis elegans)


name: Exocytosis of azurophil granule lumen proteins (Caenorhabditis elegans)


name: Exocytosis of specific granule membrane proteins (Caenorhabditis elegans)


name: Exocytosis of tertiary granule lumen proteins (Caenorhabditis elegans)


name: Exocytosis of azurophil granule membrane proteins (Caenorhabditis elegans)


name: Exocytosis of azurophil granule membrane proteins (Dictyostelium discoideum)


name: Exocytosis of tertiary granule lumen proteins (Dictyostelium discoideum)


name: Exocytosis of secretory granule membrane proteins (Dictyostelium discoideum)


name: Exocytosis of secretory granule lumen proteins (Dictyostelium discoideum)


name: Exocytosis of tertiary granule membrane proteins (Dictyostelium discoideum)


name: Exocytosis of specific granule lumen proteins (Dictyostelium discoideum)


name: Exocytosis of specific granule membrane proteins (Dictyostelium discoideum)


name: Exocytosis of azurophil granule lumen proteins (Dictyostelium discoideum)


name: Exocytosis of ficolin-rich granule membrane proteins (Dictyostelium discoideum)


name: Exocytosis of ficolin-rich granule lumen proteins (Dictyostelium discoideum)


name: Exocytosis of ficolin-rich granule lumen proteins (Schizosaccharomyces pombe)


name: Exocytosis of tertiary granule lumen proteins (Schizosaccharomyces pombe)


name: Exocytosis of specific granule membrane proteins (Schizosaccharomyces pombe)


name: Exocytosis of azurophil granule lumen proteins (Schizosaccharomyces pombe)


name: Exocytosis of secretory granule membrane proteins (Schizosaccharomyces pombe)


name: Exocytosis of ficolin-rich granule membrane proteins (Schizosaccharomyces pombe)


name: Exocytosis of secretory granule lumen proteins (Schizosaccharomyces pombe)


name: Exocytosis of tertiary granule membrane proteins (Schizosaccharomyces pombe)


name: Exocytosis of azurophil granule membrane proteins (Schizosaccharomyces pombe)


name: Exocytosis of specific granule lumen proteins (Schizosaccharomyces pombe)


name: Exocytosis of tertiary granule membrane proteins (Saccharomyces cerevisiae)


name: Exocytosis of specific granule lumen proteins (Saccharomyces cerevisiae)


name: Exocytosis of azurophil granule membrane proteins (Saccharomyces cerevisiae)


name: Exocytosis of azurophil granule lumen proteins (Saccharomyces cerevisiae)


name: Exocytosis of secretory granule membrane proteins (Saccharomyces cerevisiae)


name: Exocytosis of secretory granule lumen proteins (Saccharomyces cerevisiae)


name: Exocytosis of tertiary granule lumen proteins (Saccharomyces cerevisiae)


name: Exocytosis of ficolin-rich granule membrane proteins (Saccharomyces cerevisiae)


name: Exocytosis of specific granule membrane proteins (Saccharomyces cerevisiae)


name: Exocytosis of ficolin-rich granule lumen proteins (Saccharomyces cerevisiae)


name: Exocytosis of specific granule membrane proteins (Plasmodium falciparum)


name: Exocytosis of ficolin-rich granule lumen proteins (Plasmodium falciparum)


name: Exocytosis of tertiary granule lumen proteins (Plasmodium falciparum)


name: Exocytosis of secretory granule membrane proteins (Plasmodium falciparum)


name: Exocytosis of azurophil granule membrane proteins (Plasmodium falciparum)


name: Exocytosis of ficolin-rich granule membrane proteins (Plasmodium falciparum)


name: Exocytosis of azurophil granule lumen proteins (Plasmodium falciparum)


name: Exocytosis of secretory granule lumen proteins (Plasmodium falciparum)


name: Exocytosis of specific granule lumen proteins (Plasmodium falciparum)


name: Exocytosis of tertiary granule membrane proteins (Plasmodium falciparum)


name: Toll Like Receptor TLR1:TLR2 Cascade (Homo sapiens)

category: biolink:Pathway biolink:OntologyClass biolink:BiologicalProcess biolink:Occurrent biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent


name: TLR1/2 ligand binds to CD14 (Homo sapiens)


name: TLR1:TLR2 is recruited to ligand:CD14 (Homo sapiens)


name: Regulation of TLR by endogenous ligand (Plasmodium falciparum)


name: HMGB1 release from cells (Plasmodium falciparum)


name: Toll Like Receptor TLR6:TLR2 Cascade (Homo sapiens)


name: TLR6/2 ligand associates with CD14 and CD36 within lipid rafts (Homo sapiens)


name: TLR6:TLR2 is recruited to ligand:CD14:CD36 (Homo sapiens)


name: Toll Like Receptor 9 (TLR9) Cascade (Mus musculus)


name: Rab5-mediated recruitment of class III PI3K to TLR9 (Mus musculus)


name: Engulfed CpG DNA binds to endosomal full-length TLR9 (Mus musculus)


name: Engulfed CpG DNA binds to endosomal N-ter TLR9 dimer (Mus musculus)


name: C-ter TLR9 dimer binds HCQ (Mus musculus)


name: Engulfed CpG DNA binds to endosomal C-ter TLR9 (Mus musculus)


name: SLC15A4:TASL-dependent IRF5 activation (Mus musculus)


name: Dimerization of p-S446-IRF5 (Mus musculus)


name: Activated IKBKB phosphorylates IRF5 (Mus musculus)


name: p-S446-IRF5 dimer translocates to the nucleus (Mus musculus)


name: SLC15A4:TASL-dependent IRF5 activation (Homo sapiens)


name: Dimerization of p-S446-IRF5 (Homo sapiens)


name: Activated IKBKB phosphorylates IRF5 (Homo sapiens)


name: p-S446-IRF5 dimer translocates to the nucleus (Homo sapiens)


name: SLC15A4:TASL-dependent IRF5 activation (Rattus norvegicus)


name: TASL is phosphorylated (Rattus norvegicus)


name: p-S446-IRF5 dimer translocates to the nucleus (Rattus norvegicus)


name: Activated IKBKB phosphorylates IRF5 (Rattus norvegicus)


name: Dimerization of p-S446-IRF5 (Rattus norvegicus)


name: SLC15A4:TASL-dependent IRF5 activation (Canis familiaris)


name: Dimerization of p-S446-IRF5 (Canis familiaris)


name: p-S446-IRF5 dimer translocates to the nucleus (Canis familiaris)


name: SLC15A4:TASL-dependent IRF5 activation (Bos taurus)


name: Activated IKBKB phosphorylates IRF5 (Bos taurus)


name: Dimerization of p-S446-IRF5 (Bos taurus)


name: p-S446-IRF5 dimer translocates to the nucleus (Bos taurus)


name: SLC15A4:TASL-dependent IRF5 activation (Sus scrofa)


name: Activated IKBKB phosphorylates IRF5 (Sus scrofa)


name: Dimerization of p-S446-IRF5 (Sus scrofa)


name: p-S446-IRF5 dimer translocates to the nucleus (Sus scrofa)


name: SLC15A4:TASL-dependent IRF5 activation (Danio rerio)


name: Dimerization of p-S446-IRF5 (Danio rerio)


name: p-S446-IRF5 dimer translocates to the nucleus (Danio rerio)


name: SLC15A4:TASL-dependent IRF5 activation (Xenopus tropicalis)


name: TASL is phosphorylated (Xenopus tropicalis)


name: SLC15A4:TASL-dependent IRF5 activation (Gallus gallus)


name: p-S446-IRF5 dimer translocates to the nucleus (Gallus gallus)


name: Dimerization of p-S446-IRF5 (Gallus gallus)


name: Toll Like Receptor 9 (TLR9) Cascade (Homo sapiens)


name: Engulfed CpG DNA binds to endosomal full-length TLR9 (Homo sapiens)


name: C-ter TLR9 dimer binds HCQ (Homo sapiens)

definition: Antagonist


name: Engulfed CpG DNA binds to endosomal C-ter TLR9 (Homo sapiens)


name: Engulfed CpG DNA binds to endosomal N-ter TLR9 dimer (Homo sapiens)


name: Rab5-mediated recruitment of class III PI3K to TLR9 (Homo sapiens)


name: Toll Like Receptor 9 (TLR9) Cascade (Rattus norvegicus)


name: Engulfed CpG DNA binds to endosomal C-ter TLR9 (Rattus norvegicus)


name: C-ter TLR9 dimer binds HCQ (Rattus norvegicus)


name: Rab5-mediated recruitment of class III PI3K to TLR9 (Rattus norvegicus)


name: Engulfed CpG DNA binds to endosomal full-length TLR9 (Rattus norvegicus)


name: Engulfed CpG DNA binds to endosomal N-ter TLR9 dimer (Rattus norvegicus)


name: Toll Like Receptor 9 (TLR9) Cascade (Canis familiaris)


name: C-ter TLR9 dimer binds HCQ (Canis familiaris)


name: Engulfed CpG DNA binds to endosomal C-ter TLR9 (Canis familiaris)


name: Engulfed CpG DNA binds to endosomal full-length TLR9 (Canis familiaris)


name: Engulfed CpG DNA binds to endosomal N-ter TLR9 dimer (Canis familiaris)


name: Rab5-mediated recruitment of class III PI3K to TLR9 (Canis familiaris)


name: Toll Like Receptor 9 (TLR9) Cascade (Bos taurus)


name: Rab5-mediated recruitment of class III PI3K to TLR9 (Bos taurus)


name: Engulfed CpG DNA binds to endosomal full-length TLR9 (Bos taurus)


name: Engulfed CpG DNA binds to endosomal N-ter TLR9 dimer (Bos taurus)


name: Engulfed CpG DNA binds to endosomal C-ter TLR9 (Bos taurus)


name: Toll Like Receptor 9 (TLR9) Cascade (Sus scrofa)


name: Engulfed CpG DNA binds to endosomal N-ter TLR9 dimer (Sus scrofa)


name: Engulfed CpG DNA binds to endosomal C-ter TLR9 (Sus scrofa)


name: Engulfed CpG DNA binds to endosomal full-length TLR9 (Sus scrofa)


name: Rab5-mediated recruitment of class III PI3K to TLR9 (Sus scrofa)


name: Toll Like Receptor 7/8 (TLR7/8) Cascade (Mus musculus)


name: C-ter TLR7 dimer binds imiquimod (Mus musculus)


name: C-ter TLR7 dimer binds HCQ (Mus musculus)


name: Toll Like Receptor 7/8 (TLR7/8) Cascade (Homo sapiens)


name: C-ter TLR7 dimer binds TLR7, TLR8 ligands (Homo sapiens)


name: C-ter TLR7 dimer binds imiquimod (Homo sapiens)

definition: Agonist


name: TLR8 dimer binds TLR7, TLR8 ligands (Homo sapiens)


name: C-ter TLR7 dimer binds HCQ (Homo sapiens)


name: Toll Like Receptor 7/8 (TLR7/8) Cascade (Rattus norvegicus)


name: C-ter TLR7 dimer binds imiquimod (Rattus norvegicus)


name: C-ter TLR7 dimer binds HCQ (Rattus norvegicus)


name: Toll Like Receptor 7/8 (TLR7/8) Cascade (Canis familiaris)


name: C-ter TLR7 dimer binds imiquimod (Canis familiaris)


name: C-ter TLR7 dimer binds HCQ (Canis familiaris)


name: Toll Like Receptor 7/8 (TLR7/8) Cascade (Bos taurus)


name: C-ter TLR7 dimer binds imiquimod (Bos taurus)


name: Toll Like Receptor 7/8 (TLR7/8) Cascade (Sus scrofa)


name: C-ter TLR7 dimer binds imiquimod (Sus scrofa)


name: Toll Like Receptor 7/8 (TLR7/8) Cascade (Xenopus tropicalis)


name: C-ter TLR7 dimer binds imiquimod (Xenopus tropicalis)


name: C-ter TLR7 dimer binds HCQ (Xenopus tropicalis)


name: Toll Like Receptor 7/8 (TLR7/8) Cascade (Gallus gallus)


name: C-ter TLR7 dimer binds imiquimod (Gallus gallus)


name: C-ter TLR7 dimer binds HCQ (Gallus gallus)


name: Toll Like Receptor 4 (TLR4) Cascade (Mus musculus)


name: Transfer of LPS onto TLR4 (Mus musculus)


name: Association of LBP with LPS (Mus musculus)


name: TLR4:LY96:LPS:CD14 recruits TRAM (TICAM2) (Mus musculus)


name: Endocytosis of TRAM (TICAM2) (Mus musculus)


name: Endocytosis of TLR4:LY96:LPS:CD14 (Mus musculus)


name: Transfer of LPS from LBP carrier to CD14 (Mus musculus)


name: Transfer of LPS from LBP carrier to CD14 (Homo sapiens)


name: Transfer of LPS from LBP carrier to CD14 (Rattus norvegicus)


name: Secreted CD14 binds LPS (Rattus norvegicus)


name: GPI-bound CD14 binds LPS (Rattus norvegicus)


name: Transfer of LPS from LBP carrier to CD14 (Canis familiaris)


name: Secreted CD14 binds LPS (Canis familiaris)


name: GPI-bound CD14 binds LPS (Canis familiaris)


name: Transfer of LPS from LBP carrier to CD14 (Bos taurus)


name: Transfer of LPS from LBP carrier to CD14 (Sus scrofa)


name: Transfer of LPS from LBP carrier to CD14 (Gallus gallus)


name: GPI-bound CD14 binds LPS (Gallus gallus)


name: Interaction of DAP12 and MDL-1 (Mus musculus)


name: DAP12 interacts with NKG2C (Mus musculus)


name: Interaction of DAP12 and KIR3DS1 (Mus musculus)


name: Interaction of SIGLEC14/15/16 and DAP12 (Mus musculus)


name: Interaction of DAP12 and CLM7 (Mus musculus)


name: Interaction of DAP12 and KIR2DS2 (Mus musculus)


name: Interaction of DAP12 and KIR2DS4 (Mus musculus)


name: Interaction of DAP12 and KIR2DS5 (Mus musculus)


name: Interaction of DAP12 and IREM2 (Mus musculus)


name: Interaction of DAP12 and KIR2DS1 (Mus musculus)


name: Interaction of DAP12 and TREM1 (Mus musculus)


name: Interaction of DAP12 and TREM2 (Mus musculus)


name: Interaction of DAP12 and TREM2 (Homo sapiens)


name: DAP12 interacts with NKG2C (Homo sapiens)


name: Interaction of DAP12 and KIR2DS5 (Homo sapiens)


name: Interaction of DAP12 and MDL-1 (Homo sapiens)


name: Interaction of SIGLEC14/15/16 and DAP12 (Homo sapiens)


name: Interaction of DAP12 and KIR3DS1 (Homo sapiens)


name: Interaction of DAP12 and KIR2DS1 (Homo sapiens)


name: Interaction of DAP12 and TREM1 (Homo sapiens)


name: Interaction of DAP12 and NKG2D (Homo sapiens)


name: Interaction of DAP12 and KIR2DS4 (Homo sapiens)


name: Interaction of DAP12 and IREM2 (Homo sapiens)


name: Interaction of DAP12 and KIR2DS2 (Homo sapiens)


name: Interaction of DAP12 and CLM7 (Homo sapiens)


name: Interaction of DAP12 and NKp44 (Homo sapiens)


name: Interaction of DAP12 and IREM2 (Rattus norvegicus)


name: Interaction of DAP12 and KIR2DS4 (Rattus norvegicus)


name: Interaction of DAP12 and KIR2DS2 (Rattus norvegicus)


name: Interaction of DAP12 and TREM1 (Rattus norvegicus)


name: Interaction of DAP12 and KIR2DS5 (Rattus norvegicus)


name: DAP12 interacts with NKG2C (Rattus norvegicus)


name: Interaction of DAP12 and MDL-1 (Rattus norvegicus)


name: Interaction of DAP12 and KIR3DS1 (Rattus norvegicus)


name: Dimerization of DAP12 (Rattus norvegicus)


name: Interaction of SIGLEC14/15/16 and DAP12 (Rattus norvegicus)


name: Interaction of DAP12 and KIR2DS1 (Rattus norvegicus)


name: SIRP beta binds TYROBP (Rattus norvegicus)


name: Interaction of DAP12 and TREM2 (Rattus norvegicus)


name: Interaction of DAP12 and CLM7 (Rattus norvegicus)


name: Interaction of DAP12 and CLM7 (Canis familiaris)


name: Interaction of DAP12 and TREM2 (Canis familiaris)


name: Interaction of DAP12 and MDL-1 (Canis familiaris)


name: SIRP beta binds TYROBP (Canis familiaris)


name: DAP12 interacts with NKG2C (Canis familiaris)


name: Interaction of DAP12 and IREM2 (Canis familiaris)


name: Interaction of DAP12 and TREM1 (Canis familiaris)


name: Interaction of SIGLEC14/15/16 and DAP12 (Canis familiaris)


name: Interaction of DAP12 and NKp44 (Canis familiaris)


name: Dimerization of DAP12 (Canis familiaris)


name: Cytosolic sensors of pathogen-associated DNA  (Mus musculus)


name: MRE11 binds cytosolic DNA (Mus musculus)


name: STING mediated induction of host immune responses (Mus musculus)


name: STING binds cyclic GMP-AMP (Mus musculus)


name: DDX41 binds bacterial c-di-AMP, c-di-GMP   (Mus musculus)


name: STAT6-mediated induction of chemokines (Mus musculus)


name: TBK1 is phosphorylated within STING:TBK1:STAT6 complex (Mus musculus)


name: p-S407,Y641-STAT6 dimer migrates to the nucleus (Mus musculus)


name: p-S407-STAT6 is phosphorylated at Tyr641 (Mus musculus)


name: STING recruits TBK1 and STAT6 (Mus musculus)


name: p-S407,Y641-STAT6 is dimerized (Mus musculus)


name: TBK1 phosphorylates STAT6 at Ser407 (Mus musculus)


name: STAT6-mediated induction of chemokines (Homo sapiens)


name: TBK1 is phosphorylated within STING:TBK1:STAT6 complex (Homo sapiens)


name: p-S407,Y641-STAT6 is dimerized (Homo sapiens)


name: p-S407,Y641-STAT6 dimer migrates to the nucleus (Homo sapiens)


name: TBK1 phosphorylates STAT6 at Ser407 (Homo sapiens)


name: STING recruits TBK1 and STAT6 (Homo sapiens)


name: p-S407-STAT6 is phosphorylated at Tyr641 (Homo sapiens)


name: STAT6-mediated induction of chemokines (Rattus norvegicus)


name: p-S407,Y641-STAT6 dimer migrates to the nucleus (Rattus norvegicus)


name: p-S407-STAT6 is phosphorylated at Tyr641 (Rattus norvegicus)


name: TBK1 is phosphorylated within STING:TBK1:STAT6 complex (Rattus norvegicus)


name: STING recruits TBK1 and STAT6 (Rattus norvegicus)


name: TBK1 phosphorylates STAT6 at Ser407 (Rattus norvegicus)


name: p-S407,Y641-STAT6 is dimerized (Rattus norvegicus)


name: STAT6-mediated induction of chemokines (Canis familiaris)


name: p-S407,Y641-STAT6 dimer migrates to the nucleus (Canis familiaris)


name: p-S407,Y641-STAT6 is dimerized (Canis familiaris)


name: p-S407-STAT6 is phosphorylated at Tyr641 (Canis familiaris)


name: STAT6-mediated induction of chemokines (Bos taurus)


name: STING recruits TBK1 and STAT6 (Bos taurus)


name: p-S407,Y641-STAT6 dimer migrates to the nucleus (Bos taurus)


name: TBK1 is phosphorylated within STING:TBK1:STAT6 complex (Bos taurus)


name: p-S407-STAT6 is phosphorylated at Tyr641 (Bos taurus)


name: p-S407,Y641-STAT6 is dimerized (Bos taurus)


name: TBK1 phosphorylates STAT6 at Ser407 (Bos taurus)


name: STAT6-mediated induction of chemokines (Sus scrofa)


name: TBK1 phosphorylates STAT6 at Ser407 (Sus scrofa)


name: p-S407,Y641-STAT6 is dimerized (Sus scrofa)


name: STING recruits TBK1 and STAT6 (Sus scrofa)


name: p-S407-STAT6 is phosphorylated at Tyr641 (Sus scrofa)


name: p-S407,Y641-STAT6 dimer migrates to the nucleus (Sus scrofa)


name: TBK1 is phosphorylated within STING:TBK1:STAT6 complex (Sus scrofa)


name: STAT6-mediated induction of chemokines (Danio rerio)


name: p-S407,Y641-STAT6 dimer migrates to the nucleus (Danio rerio)


name: TBK1 is phosphorylated within STING:TBK1:STAT6 complex (Danio rerio)


name: p-S407-STAT6 is phosphorylated at Tyr641 (Danio rerio)


name: STING recruits TBK1 and STAT6 (Danio rerio)


name: p-S407,Y641-STAT6 is dimerized (Danio rerio)


name: TBK1 phosphorylates STAT6 at Ser407 (Danio rerio)


name: STAT6-mediated induction of chemokines (Xenopus tropicalis)


name: TBK1 phosphorylates STAT6 at Ser407 (Xenopus tropicalis)


name: TBK1 is phosphorylated within STING:TBK1:STAT6 complex (Xenopus tropicalis)


name: p-S407-STAT6 is phosphorylated at Tyr641 (Xenopus tropicalis)


name: STING recruits TBK1 and STAT6 (Xenopus tropicalis)


name: p-S407,Y641-STAT6 dimer migrates to the nucleus (Xenopus tropicalis)


name: p-S407,Y641-STAT6 is dimerized (Xenopus tropicalis)


name: STAT6-mediated induction of chemokines (Drosophila melanogaster)


name: p-S407-STAT6 is phosphorylated at Tyr641 (Drosophila melanogaster)


name: STING recruits TBK1 and STAT6 (Drosophila melanogaster)


name: TBK1 is phosphorylated within STING:TBK1:STAT6 complex (Drosophila melanogaster)


name: p-S407,Y641-STAT6 is dimerized (Drosophila melanogaster)


name: p-S407,Y641-STAT6 dimer migrates to the nucleus (Drosophila melanogaster)


name: TBK1 phosphorylates STAT6 at Ser407 (Drosophila melanogaster)


name: STAT6-mediated induction of chemokines (Caenorhabditis elegans)


name: p-S407-STAT6 is phosphorylated at Tyr641 (Caenorhabditis elegans)


name: p-S407,Y641-STAT6 dimer migrates to the nucleus (Caenorhabditis elegans)


name: p-S407,Y641-STAT6 is dimerized (Caenorhabditis elegans)


name: STAT6-mediated induction of chemokines (Dictyostelium discoideum)


name: p-S407-STAT6 is phosphorylated at Tyr641 (Dictyostelium discoideum)


name: p-S407,Y641-STAT6 dimer migrates to the nucleus (Dictyostelium discoideum)


name: p-S407,Y641-STAT6 is dimerized (Dictyostelium discoideum)


name: IRF3-mediated induction of type I IFN (Mus musculus)


name: Dimerized phospho-IRF3 migrates to the nucleus (Mus musculus)


name: TBK1 is phosphorylated within STING:TBK1:IRF3 complex (Mus musculus)


name: IRF3 is phosphorylated by TBK1 (Mus musculus)


name: IRF3-mediated induction of type I IFN (Homo sapiens)


name: TBK1 is phosphorylated within STING:TBK1:IRF3 complex (Homo sapiens)


name: Dimerized phospho-IRF3 migrates to the nucleus (Homo sapiens)


name: IRF3 is phosphorylated by TBK1 (Homo sapiens)


name: STING recruits TBK1 and IRF3 (Homo sapiens)


name: IRF3-mediated induction of type I IFN (Rattus norvegicus)


name: Dimerized phospho-IRF3 migrates to the nucleus (Rattus norvegicus)


name: TBK1 is phosphorylated within STING:TBK1:IRF3 complex (Rattus norvegicus)


name: IRF3 is phosphorylated by TBK1 (Rattus norvegicus)


name: p-T,4S-IRF3 is dimerized (Rattus norvegicus)


name: IRF3-mediated induction of type I IFN (Canis familiaris)


name: Dimerized phospho-IRF3 migrates to the nucleus (Canis familiaris)


name: p-T,4S-IRF3 is dimerized (Canis familiaris)


name: IRF3-mediated induction of type I IFN (Bos taurus)


name: IRF3 is phosphorylated by TBK1 (Bos taurus)


name: TBK1 is phosphorylated within STING:TBK1:IRF3 complex (Bos taurus)


name: Dimerized phospho-IRF3 migrates to the nucleus (Bos taurus)


name: IRF3-mediated induction of type I IFN (Sus scrofa)


name: Dimerized phospho-IRF3 migrates to the nucleus (Sus scrofa)


name: IRF3 is phosphorylated by TBK1 (Sus scrofa)


name: TBK1 is phosphorylated within STING:TBK1:IRF3 complex (Sus scrofa)


name: STING mediated induction of host immune responses (Homo sapiens)


name: IFI16 binds cytosolic dsDNA (Homo sapiens)


name: cGAS produces cyclic GMP-AMP (Homo sapiens)


name: DDX41 binds bacterial c-di-AMP, c-di-GMP   (Homo sapiens)


name: STING binds cyclic GMP-AMP (Homo sapiens)


name: STING mediated induction of host immune responses (Rattus norvegicus)


name: STING binds c-di-GMP (Rattus norvegicus)


name: DDX41 binds bacterial c-di-AMP, c-di-GMP   (Rattus norvegicus)


name: STING binds cyclic GMP-AMP (Rattus norvegicus)


name: STING mediated induction of host immune responses (Canis familiaris)


name: DDX41 binds bacterial c-di-AMP, c-di-GMP   (Canis familiaris)


name: STING mediated induction of host immune responses (Bos taurus)


name: DDX41 binds bacterial c-di-AMP, c-di-GMP   (Bos taurus)


name: STING mediated induction of host immune responses (Sus scrofa)


name: DDX41 binds bacterial c-di-AMP, c-di-GMP   (Sus scrofa)


name: STING mediated induction of host immune responses (Danio rerio)


name: STING binds cyclic GMP-AMP (Danio rerio)


name: STING mediated induction of host immune responses (Xenopus tropicalis)


name: STING binds c-di-GMP (Xenopus tropicalis)


name: DDX41 binds bacterial c-di-AMP, c-di-GMP   (Xenopus tropicalis)


name: STING binds cyclic GMP-AMP (Xenopus tropicalis)


name: STING mediated induction of host immune responses (Gallus gallus)


name: STING binds cyclic GMP-AMP (Gallus gallus)


name: DDX41 binds bacterial c-di-AMP, c-di-GMP   (Gallus gallus)


name: STING mediated induction of host immune responses (Drosophila melanogaster)


name: STING dimerization (Drosophila melanogaster)


name: STING binds cyclic GMP-AMP (Drosophila melanogaster)


name: DDX41 binds bacterial c-di-AMP, c-di-GMP   (Drosophila melanogaster)


name: STING binds c-di-GMP (Drosophila melanogaster)


name: STING mediated induction of host immune responses (Caenorhabditis elegans)


name: DDX41 binds bacterial c-di-AMP, c-di-GMP   (Caenorhabditis elegans)


name: STING mediated induction of host immune responses (Dictyostelium discoideum)


name: DDX41 binds bacterial c-di-AMP, c-di-GMP   (Dictyostelium discoideum)


name: DEx/H-box helicases activate type I IFN and inflammatory cytokines production  (Mus musculus)


name: DHX36 or DHX9 binds MyD88 (Mus musculus)


name: p-IRF7:p-IRF7 translocates to the nucleus (Mus musculus)


name: NFkB complex translocates from the cytosol to the nucleus (Mus musculus)


name: DEx/H-box helicases activate type I IFN and inflammatory cytokines production  (Homo sapiens)


name: DHX36 or DHX9 binds MyD88 (Homo sapiens)


name: p-IRF7:p-IRF7 translocates to the nucleus (Homo sapiens)


name: NFkB complex translocates from the cytosol to the nucleus (Homo sapiens)


name: DEx/H-box helicases activate type I IFN and inflammatory cytokines production  (Rattus norvegicus)


name: DHX36 or DHX9 binds MyD88 (Rattus norvegicus)


name: NFkB complex translocates from the cytosol to the nucleus (Rattus norvegicus)


name: p-IRF7:p-IRF7 translocates to the nucleus (Rattus norvegicus)


name: DEx/H-box helicases activate type I IFN and inflammatory cytokines production  (Canis familiaris)


name: NFkB complex translocates from the cytosol to the nucleus (Canis familiaris)


name: DHX36 or DHX9 binds MyD88 (Canis familiaris)


name: DEx/H-box helicases activate type I IFN and inflammatory cytokines production  (Bos taurus)


name: p-IRF7:p-IRF7 translocates to the nucleus (Bos taurus)


name: NFkB complex translocates from the cytosol to the nucleus (Bos taurus)


name: DEx/H-box helicases activate type I IFN and inflammatory cytokines production  (Sus scrofa)


name: NFkB complex translocates from the cytosol to the nucleus (Sus scrofa)


name: p-IRF7:p-IRF7 translocates to the nucleus (Sus scrofa)


name: DEx/H-box helicases activate type I IFN and inflammatory cytokines production  (Danio rerio)


name: NFkB complex translocates from the cytosol to the nucleus (Danio rerio)


name: DEx/H-box helicases activate type I IFN and inflammatory cytokines production  (Xenopus tropicalis)


name: DHX36 or DHX9 binds MyD88 (Xenopus tropicalis)


name: p-IRF7:p-IRF7 translocates to the nucleus (Xenopus tropicalis)


name: DEx/H-box helicases activate type I IFN and inflammatory cytokines production  (Gallus gallus)


name: DHX36 or DHX9 binds MyD88 (Gallus gallus)


name: NFkB complex translocates from the cytosol to the nucleus (Gallus gallus)


name: p-IRF7:p-IRF7 translocates to the nucleus (Gallus gallus)


name: DEx/H-box helicases activate type I IFN and inflammatory cytokines production  (Drosophila melanogaster)


name: DHX36 binds DNA (Drosophila melanogaster)


name: NFkB complex translocates from the cytosol to the nucleus (Drosophila melanogaster)


name: DHX9 binds DNA (Drosophila melanogaster)


name: DHX36 or DHX9 binds MyD88 (Drosophila melanogaster)


name: DEx/H-box helicases activate type I IFN and inflammatory cytokines production  (Caenorhabditis elegans)


name: DEx/H-box helicases activate type I IFN and inflammatory cytokines production  (Dictyostelium discoideum)


name: DHX9 binds DNA (Dictyostelium discoideum)


name: DHX36 binds DNA (Dictyostelium discoideum)


name: Regulation of innate immune responses to cytosolic DNA (Mus musculus)


name: NLRP4 and DTX4 associate with p-S172-TBK1 within STING:TBK1:IRF3 (Mus musculus)


name: DTX4 ubiquitinates p-S172-TBK1 within NLRP4:DTX4:STING:TBK1:IRF3 (Mus musculus)


name: STING binds TRIM32 or TRIM56  (Mus musculus)


name: STING ubiquitination by TRIM32 or TRIM56 (Mus musculus)


name: DDX41 ubiquitination by TRIM21 (Mus musculus)


name: Regulation of innate immune responses to cytosolic DNA (Homo sapiens)


name: DTX4 ubiquitinates p-S172-TBK1 within NLRP4:DTX4:STING:TBK1:IRF3 (Homo sapiens)


name: STING binds TRIM32 or TRIM56  (Homo sapiens)


name: DDX41 ubiquitination by TRIM21 (Homo sapiens)


name: DTX4 ubiquitinates p-S172-TBK1 within NLRP4:DTX4:dsDNA:ZBP1:TBK1 (Homo sapiens)


name: STING ubiquitination by TRIM32 or TRIM56 (Homo sapiens)


name: NLRP4 and DTX4 associate with p-S172-TBK1 within dsDNA:ZBP1:TBK1 (Homo sapiens)


name: NLRP4 and DTX4 associate with p-S172-TBK1 within STING:TBK1:IRF3 (Homo sapiens)


name: TREX1 binds retroviral-derived DNA (Homo sapiens)


3'-5' exonuclease activity

description: Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 3' end.


name: Regulation of innate immune responses to cytosolic DNA (Rattus norvegicus)


name: DTX4 ubiquitinates p-S172-TBK1 within NLRP4:DTX4:STING:TBK1:IRF3 (Rattus norvegicus)


name: STING ubiquitination by TRIM32 or TRIM56 (Rattus norvegicus)


name: STING binds TRIM32 or TRIM56  (Rattus norvegicus)


name: DDX41 ubiquitination by TRIM21 (Rattus norvegicus)


name: NLRP4 and DTX4 associate with p-S172-TBK1 within STING:TBK1:IRF3 (Rattus norvegicus)


name: Regulation of innate immune responses to cytosolic DNA (Canis familiaris)


name: DDX41 ubiquitination by TRIM21 (Canis familiaris)


name: Regulation of innate immune responses to cytosolic DNA (Bos taurus)


name: STING binds TRIM32 or TRIM56  (Bos taurus)


name: DDX41 ubiquitination by TRIM21 (Bos taurus)


name: STING ubiquitination by TRIM32 or TRIM56 (Bos taurus)


name: Regulation of innate immune responses to cytosolic DNA (Sus scrofa)


name: DDX41 ubiquitination by TRIM21 (Sus scrofa)


name: STING binds TRIM32 or TRIM56  (Sus scrofa)


name: STING ubiquitination by TRIM32 or TRIM56 (Sus scrofa)


name: DTX4 ubiquitinates p-S172-TBK1 within NLRP4:DTX4:STING:TBK1:IRF3 (Sus scrofa)


name: NLRP4 and DTX4 associate with p-S172-TBK1 within STING:TBK1:IRF3 (Sus scrofa)


name: Regulation of innate immune responses to cytosolic DNA (Danio rerio)


name: STING binds TRIM32 or TRIM56  (Danio rerio)


name: STING ubiquitination by TRIM32 or TRIM56 (Danio rerio)


name: Regulation of innate immune responses to cytosolic DNA (Xenopus tropicalis)


name: DDX41 ubiquitination by TRIM21 (Xenopus tropicalis)


name: Regulation of innate immune responses to cytosolic DNA (Gallus gallus)


name: DDX41 ubiquitination by TRIM21 (Gallus gallus)


name: Regulation of innate immune responses to cytosolic DNA (Drosophila melanogaster)


name: STING ubiquitination by TRIM32 or TRIM56 (Drosophila melanogaster)


name: STING binds TRIM32 or TRIM56  (Drosophila melanogaster)


name: Regulation of innate immune responses to cytosolic DNA (Caenorhabditis elegans)


name: DDX41 ubiquitination by TRIM21 (Caenorhabditis elegans)


name: IRF3 mediated activation of type 1 IFN (Mus musculus)


name: IRF3 mediated activation of type 1 IFN (Homo sapiens)


name: Phosphorylation and release of IRF3  (Homo sapiens)


name: Recruitment TBK1 to dsDNA:ZBP1 followed by its activation (Homo sapiens)


TBK1 binds amlexanox (Homo sapiens)

definition: Inhibition


name: Recruitment of IRF3 to activated ZBP1:TBK1 (Homo sapiens)


name: IRF3 mediated activation of type 1 IFN (Rattus norvegicus)


name: IRF3 mediated activation of type 1 IFN (Canis familiaris)


name: IRF3 mediated activation of type 1 IFN (Bos taurus)


name: IRF3 mediated activation of type 1 IFN (Sus scrofa)


name: RIP-mediated NFkB activation via ZBP1 (Mus musculus)


name: RIP-mediated NFkB activation via ZBP1 (Homo sapiens)


name: RIP1 facilitates IKK complex phosphorylation (Homo sapiens)


name: ZBP1(DAI) recruits RIP1 and RIP3 (Homo sapiens)


name: RIP-mediated NFkB activation via ZBP1 (Rattus norvegicus)


name: RIP-mediated NFkB activation via ZBP1 (Canis familiaris)


name: RIP-mediated NFkB activation via ZBP1 (Bos taurus)


name: RIP-mediated NFkB activation via ZBP1 (Sus scrofa)


name: RIP-mediated NFkB activation via ZBP1 (Danio rerio)


name: RIP-mediated NFkB activation via ZBP1 (Gallus gallus)


name: RIP-mediated NFkB activation via ZBP1 (Drosophila melanogaster)


name: ZBP1(DAI) mediated induction of type I IFNs (Homo sapiens)


name: LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production (Mus musculus)


name: Beta-catenin migrates to the nucleus (Mus musculus)


name: Beta-catenin enhances association of IRF3 with CBP/p300  (Mus musculus)


name: LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production (Homo sapiens)


name: LRR FLII-interacting protein 1 binds dsDNA (Homo sapiens)


name: Beta-catenin migrates to the nucleus (Homo sapiens)


name: Beta-catenin enhances association of IRF3 with CBP/p300  (Homo sapiens)


name: LRR FLII-interacting protein 1 associates with beta-catenin (Homo sapiens)


name: Phosphorylation of beta-catenin at Ser552 (Homo sapiens)


name: LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production (Rattus norvegicus)


name: Beta-catenin migrates to the nucleus (Rattus norvegicus)


name: Beta-catenin enhances association of IRF3 with CBP/p300  (Rattus norvegicus)


name: LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production (Canis familiaris)


name: Beta-catenin enhances association of IRF3 with CBP/p300  (Canis familiaris)


name: Beta-catenin migrates to the nucleus (Canis familiaris)


name: LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production (Bos taurus)


name: Beta-catenin enhances association of IRF3 with CBP/p300  (Bos taurus)


name: Beta-catenin migrates to the nucleus (Bos taurus)


name: LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production (Sus scrofa)


name: Beta-catenin migrates to the nucleus (Sus scrofa)


name: Beta-catenin enhances association of IRF3 with CBP/p300  (Sus scrofa)


name: LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production (Danio rerio)


name: Beta-catenin migrates to the nucleus (Danio rerio)


name: LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production (Xenopus tropicalis)


name: Beta-catenin migrates to the nucleus (Xenopus tropicalis)


name: LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production (Gallus gallus)


name: Beta-catenin migrates to the nucleus (Gallus gallus)


name: LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production (Drosophila melanogaster)


name: Beta-catenin migrates to the nucleus (Drosophila melanogaster)


name: LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production (Caenorhabditis elegans)


name: Beta-catenin migrates to the nucleus (Caenorhabditis elegans)


name: DDX58/IFIH1-mediated induction of interferon-alpha/beta (Mus musculus)


name: HSP90 binds TBK1 and IRF3 (Mus musculus)


name: Cytosolic sensors of pathogen-associated DNA  (Homo sapiens)


name: MRE11 binds cytosolic DNA (Homo sapiens)


RNA polymerase III activity

description: Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template that contains an RNA polymerase III specific promoter to direct initiation and catalyses DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.


name: DNA-PK binds microbial dsDNA (Homo sapiens)


name: Cytosolic sensors of pathogen-associated DNA  (Rattus norvegicus)


name: MRE11 binds cytosolic DNA (Rattus norvegicus)


name: DDX58/IFIH1-mediated induction of interferon-alpha/beta (Rattus norvegicus)


name: HSP90 binds TBK1 and IRF3 (Rattus norvegicus)


name: Cytosolic sensors of pathogen-associated DNA  (Canis familiaris)


name: MRE11 binds cytosolic DNA (Canis familiaris)


name: DDX58/IFIH1-mediated induction of interferon-alpha/beta (Canis familiaris)


name: HSP90 binds TBK1 and IRF3 (Canis familiaris)


name: Cytosolic sensors of pathogen-associated DNA  (Bos taurus)


name: DDX58/IFIH1-mediated induction of interferon-alpha/beta (Bos taurus)


name: Cytosolic sensors of pathogen-associated DNA  (Sus scrofa)


name: DDX58/IFIH1-mediated induction of interferon-alpha/beta (Sus scrofa)


name: DDX58/IFIH1-mediated induction of interferon-alpha/beta (Danio rerio)


name: Cytosolic sensors of pathogen-associated DNA  (Xenopus tropicalis)


name: MRE11 binds cytosolic DNA (Xenopus tropicalis)


name: Cytosolic sensors of pathogen-associated DNA  (Gallus gallus)


name: MRE11 binds cytosolic DNA (Gallus gallus)


name: DDX58/IFIH1-mediated induction of interferon-alpha/beta (Gallus gallus)


name: Cytosolic sensors of pathogen-associated DNA  (Drosophila melanogaster)


name: MRE11 binds cytosolic DNA (Drosophila melanogaster)


name: Cytosolic sensors of pathogen-associated DNA  (Caenorhabditis elegans)


name: MRE11 binds cytosolic DNA (Caenorhabditis elegans)


name: Cytosolic sensors of pathogen-associated DNA  (Dictyostelium discoideum)


name: MRE11 binds cytosolic DNA (Dictyostelium discoideum)


name: Cytosolic sensors of pathogen-associated DNA  (Schizosaccharomyces pombe)


name: MRE11 binds cytosolic DNA (Schizosaccharomyces pombe)


name: Cytosolic sensors of pathogen-associated DNA  (Saccharomyces cerevisiae)


name: MRE11 binds cytosolic DNA (Saccharomyces cerevisiae)


name: Cytosolic sensors of pathogen-associated DNA  (Plasmodium falciparum)


name: MRE11 binds cytosolic DNA (Plasmodium falciparum)


name: Advanced glycosylation endproduct receptor signaling (Mus musculus)


name: The TRTK-12 fragment of F-actin capping protein alpha binds the AGER ligand S100B (Mus musculus)


name: Advanced glycosylation end product-specific receptor (AGER/RAGE) is a multiligand receptor (Mus musculus)


name: Advanced glycosylation endproduct receptor signaling (Homo sapiens)


name: Advanced glycosylation end product-specific receptor (AGER/RAGE) is a multiligand receptor (Homo sapiens)


name: The TRTK-12 fragment of F-actin capping protein alpha binds the AGER ligand S100B (Homo sapiens)


name: Advanced glycosylation endproduct receptor signaling (Rattus norvegicus)


name: Advanced glycosylation end product-specific receptor (AGER/RAGE) is a multiligand receptor (Rattus norvegicus)


name: The TRTK-12 fragment of F-actin capping protein alpha binds the AGER ligand S100B (Rattus norvegicus)


name: Advanced glycosylation endproduct receptor signaling (Canis familiaris)


name: Advanced glycosylation end product-specific receptor (AGER/RAGE) is a multiligand receptor (Canis familiaris)


name: Advanced glycosylation endproduct receptor signaling (Bos taurus)


name: The TRTK-12 fragment of F-actin capping protein alpha binds the AGER ligand S100B (Bos taurus)


name: Advanced glycosylation end product-specific receptor (AGER/RAGE) is a multiligand receptor (Bos taurus)


name: Advanced glycosylation endproduct receptor signaling (Sus scrofa)


name: The TRTK-12 fragment of F-actin capping protein alpha binds the AGER ligand S100B (Sus scrofa)


name: Advanced glycosylation end product-specific receptor (AGER/RAGE) is a multiligand receptor (Sus scrofa)


name: Advanced glycosylation endproduct receptor signaling (Danio rerio)


name: The TRTK-12 fragment of F-actin capping protein alpha binds the AGER ligand S100B (Danio rerio)


name: Advanced glycosylation endproduct receptor signaling (Xenopus tropicalis)


name: Advanced glycosylation end product-specific receptor (AGER/RAGE) is a multiligand receptor (Xenopus tropicalis)


name: Advanced glycosylation endproduct receptor signaling (Gallus gallus)


name: The TRTK-12 fragment of F-actin capping protein alpha binds the AGER ligand S100B (Gallus gallus)


name: Advanced glycosylation endproduct receptor signaling (Dictyostelium discoideum)


name: Advanced glycosylation end product-specific receptor (AGER/RAGE) is a multiligand receptor (Dictyostelium discoideum)


name: ELANE, CTSG or PRTN3 binds bacteria (Mus musculus)


name: RNASEs bind bacterial LPS, PGN (Mus musculus)


name: INTL1 binds bacterial glycans (Mus musculus)


name: Cathelicidin LL-37 binds to bacterial cell wall (Mus musculus)


name: REG3A oligomerize to form a pore complex (Mus musculus)


name: PGLYRP1 binds bacterial peptidoglycan (Mus musculus)


name: CHGA-derived peptide binds the bacterial cell surface (Mus musculus)


name: Trypsin cleaves REG3A or REG3G to generate REG3A,G(38-175) (Mus musculus)


name: LYZ hydrolyzes peptidoglycans in the bacterial cell wall (Mus musculus)


name: LYZ binds bacterial peptidoglycan (Mus musculus)


name: REG3A,REG3G binds bacterial peptidoglycan (Mus musculus)


name: EPPIN protein complex binds bacteria (Mus musculus)


name: REG3A binds bacterial phospholipids (Mus musculus)


name: PGLYRP3,4 binds bacterial peptidoglycan (Mus musculus)


name: PRTN3 cleaves CAMP(31-170) to generate CAMP(134-170) (Mus musculus)


name: PGLYRP2 binds bacterial peptidoglycan (Mus musculus)


name: RNASEs bind bacterial phospholipids (Mus musculus)


name: PGLYRP2 hydrolyzes bacterial peptidoglycan (Mus musculus)


name: PLA2G2A binds bacterial phospholipids (Mus musculus)


name: BPI binds LPS on the bacterial surface (Mus musculus)


name: Ion influx/efflux at host-pathogen interface (Mus musculus)


name: ATP7A transports cytosolic Cu2+ to phagosomal lumen (Mus musculus)


name: NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages (Mus musculus)


name: Ion influx/efflux at host-pathogen interface (Homo sapiens)


name: ATP7A transports cytosolic Cu2+ to phagosomal lumen (Homo sapiens)


metal cation:proton antiporter activity

description: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: metal ion(in) + H+(out) = metal ion(out) + H+(in).


name: Ion influx/efflux at host-pathogen interface (Rattus norvegicus)


name: NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages (Rattus norvegicus)


name: ATP7A transports cytosolic Cu2+ to phagosomal lumen (Rattus norvegicus)


name: Ion influx/efflux at host-pathogen interface (Canis familiaris)


name: ATP7A transports cytosolic Cu2+ to phagosomal lumen (Canis familiaris)


name: NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages (Canis familiaris)


name: Ion influx/efflux at host-pathogen interface (Bos taurus)


name: NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages (Bos taurus)


name: Ion influx/efflux at host-pathogen interface (Sus scrofa)


name: ATP7A transports cytosolic Cu2+ to phagosomal lumen (Sus scrofa)


name: NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages (Sus scrofa)


name: Ion influx/efflux at host-pathogen interface (Danio rerio)


name: ATP7A transports cytosolic Cu2+ to phagosomal lumen (Danio rerio)


name: NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages (Danio rerio)


name: Ion influx/efflux at host-pathogen interface (Xenopus tropicalis)


name: NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages (Xenopus tropicalis)


name: ATP7A transports cytosolic Cu2+ to phagosomal lumen (Xenopus tropicalis)


name: Ion influx/efflux at host-pathogen interface (Gallus gallus)


name: NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages (Gallus gallus)


name: ATP7A transports cytosolic Cu2+ to phagosomal lumen (Gallus gallus)


name: Ion influx/efflux at host-pathogen interface (Drosophila melanogaster)


name: NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages (Drosophila melanogaster)


name: Ion influx/efflux at host-pathogen interface (Caenorhabditis elegans)


name: NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages (Caenorhabditis elegans)


name: Ion influx/efflux at host-pathogen interface (Dictyostelium discoideum)


name: NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages (Dictyostelium discoideum)


name: Ion influx/efflux at host-pathogen interface (Plasmodium falciparum)


name: NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages (Plasmodium falciparum)


name: Metal sequestration by antimicrobial proteins (Mus musculus)


name: Lactoferrin scavenges iron ions (Mus musculus)


name: Metal sequestration by antimicrobial proteins (Homo sapiens)


name: S100A7 or S100A7A binds Zn2+ (Homo sapiens)


name: Lactoferrin scavenges iron ions (Homo sapiens)


name: Metal sequestration by antimicrobial proteins (Rattus norvegicus)


name: Lactoferrin scavenges iron ions (Rattus norvegicus)


name: S100A8:S100A9 binds Mn2+ (Rattus norvegicus)


name: S100A8:S100A9 binds Zn2+ (Rattus norvegicus)


name: Metal sequestration by antimicrobial proteins (Canis familiaris)


name: S100A8:S100A9 binds Zn2+ (Canis familiaris)


name: S100A8:S100A9 binds Mn2+ (Canis familiaris)


name: Lactoferrin scavenges iron ions (Canis familiaris)


name: Metal sequestration by antimicrobial proteins (Bos taurus)


name: Lactoferrin scavenges iron ions (Bos taurus)


name: S100A7 or S100A7A binds Zn2+ (Bos taurus)


name: Metal sequestration by antimicrobial proteins (Sus scrofa)


name: Lactoferrin scavenges iron ions (Sus scrofa)


name: S100A7 or S100A7A binds Zn2+ (Sus scrofa)


name: Metal sequestration by antimicrobial proteins (Danio rerio)


name: S100A7 or S100A7A binds Zn2+ (Danio rerio)


name: Metal sequestration by antimicrobial proteins (Xenopus tropicalis)


name: S100A8:S100A9 binds Mn2+ (Xenopus tropicalis)


name: S100A7 or S100A7A binds Zn2+ (Xenopus tropicalis)


name: Lactoferrin scavenges iron ions (Xenopus tropicalis)


name: LCN2:2,5DHBA binds Fe3+ (Xenopus tropicalis)


name: S100A8:S100A9 binds Zn2+ (Xenopus tropicalis)


name: Metal sequestration by antimicrobial proteins (Gallus gallus)


name: Lactoferrin scavenges iron ions (Gallus gallus)


name: S100A8:S100A9 binds Mn2+ (Gallus gallus)


name: S100A7 or S100A7A binds Zn2+ (Gallus gallus)


name: S100A8:S100A9 binds Zn2+ (Gallus gallus)


name: Metal sequestration by antimicrobial proteins (Drosophila melanogaster)


name: Lactoferrin scavenges iron ions (Drosophila melanogaster)


name: Pre-pro-defensins are cleaved to remove the signal peptide (Mus musculus)


name: ADP-Ribosylation of HNP-1 (Mus musculus)


name: Pro-HNP1-4 are cleaved to biologically active defensin (Mus musculus)


name: Alpha-defensin dimers multimerize to form a pore complex (Mus musculus)


name: HNP1-4 are stored in primary neutrophil granules (Mus musculus)


name: pro-defensin alpha 5 is secreted (Mus musculus)


name: pro-defensin alpha 5 is stored in Paneth cell granules (Mus musculus)


name: HNP1-4 are released into phagocytic vacuoles (Mus musculus)


name: Alpha-defensins form biologically active dimers (Mus musculus)


name: pro-HD5 is cleaved by trypsin (Mus musculus)


name: Alpha-defensin dimers adsorb onto microbial membrane anionic phospholipids (Mus musculus)


name: ADP-Ribosylation of HNP-1 (Homo sapiens)


name: pro-HD5 is cleaved by trypsin (Homo sapiens)


name: HNP1-4 are released into phagocytic vacuoles (Homo sapiens)


name: pro-defensin alpha 5 is stored in Paneth cell granules (Homo sapiens)


name: Alpha-defensin dimers multimerize to form a pore complex (Homo sapiens)


name: Alpha-defensins form biologically active dimers (Homo sapiens)


name: Alpha-defensin dimers adsorb onto microbial membrane anionic phospholipids (Homo sapiens)


name: HNP1-4 are stored in primary neutrophil granules (Homo sapiens)


name: pro-defensin alpha 5 is secreted (Homo sapiens)


name: Pro-HNP1-4 are cleaved to biologically active defensin (Homo sapiens)


name: Alpha-defensin dimers multimerize to form a pore complex (Rattus norvegicus)


name: pro-defensin alpha 5 is stored in Paneth cell granules (Rattus norvegicus)


name: HNP1-4 are released into phagocytic vacuoles (Rattus norvegicus)


name: Alpha-defensin dimers adsorb onto microbial membrane anionic phospholipids (Rattus norvegicus)


name: Alpha-defensins form biologically active dimers (Rattus norvegicus)


name: Pro-HNP1-4 are cleaved to biologically active defensin (Rattus norvegicus)


name: pro-HD5 is cleaved by trypsin (Rattus norvegicus)


name: ADP-Ribosylation of HNP-1 (Rattus norvegicus)


name: pro-defensin alpha 5 is secreted (Rattus norvegicus)


name: HNP1-4 are stored in primary neutrophil granules (Rattus norvegicus)


name: Beta-defensins are secreted (Mus musculus)


name: Beta-defensins 1, 4A and 103 bind CCR6 (Mus musculus)


name: Beta-defensins bind microbial membranes causing disruption (Mus musculus)


name: Beta defensin 103 activates TLR1:TLR2 (Mus musculus)


name: Beta-defensins 4A and 103 bind CCR2 (Homo sapiens)


name: Beta-defensins 1, 4A and 103 bind CCR6 (Homo sapiens)


name: Beta-defensins are secreted (Homo sapiens)


name: Beta defensin 103 activates TLR1:TLR2 (Homo sapiens)


name: Beta-defensins bind microbial membranes causing disruption (Homo sapiens)


name: Beta-defensins 1, 4A and 103 bind CCR6 (Rattus norvegicus)


name: Beta defensin 103 activates TLR1:TLR2 (Rattus norvegicus)


name: Beta-defensins are secreted (Rattus norvegicus)


name: Beta-defensins bind microbial membranes causing disruption (Rattus norvegicus)


name: Beta-defensins 1, 4A and 103 bind CCR6 (Canis familiaris)


name: Beta-defensins 4A and 103 bind CCR2 (Canis familiaris)


name: Beta-defensins are secreted (Bos taurus)


name: Beta-defensins 4A and 103 bind CCR2 (Bos taurus)


name: Beta-defensins bind microbial membranes causing disruption (Bos taurus)


name: Beta-defensins 1, 4A and 103 bind CCR6 (Bos taurus)


name: Beta-defensins are secreted (Sus scrofa)


name: Beta defensin 103 activates TLR1:TLR2 (Sus scrofa)


name: Beta-defensins bind microbial membranes causing disruption (Sus scrofa)


name: Beta-defensins 4A and 103 bind CCR2 (Sus scrofa)


name: Beta-defensins 1, 4A and 103 bind CCR6 (Sus scrofa)


name: Beta-defensins are secreted (Gallus gallus)


name: Beta defensin 103 activates TLR1:TLR2 (Gallus gallus)


name: Beta-defensins 4A and 103 bind CCR2 (Gallus gallus)


name: Beta-defensins 1, 4A and 103 bind CCR6 (Gallus gallus)


name: Beta-defensins bind microbial membranes causing disruption (Gallus gallus)


name: Binding of defensins to lipid II (Homo sapiens)


name: Pre-pro-defensins are cleaved to remove the signal peptide (Homo sapiens)


name: Pre-pro-defensins are cleaved to remove the signal peptide (Rattus norvegicus)


name: Pre-pro-defensins are cleaved to remove the signal peptide (Canis familiaris)


name: Pre-pro-defensins are cleaved to remove the signal peptide (Bos taurus)


name: Pre-pro-defensins are cleaved to remove the signal peptide (Sus scrofa)


name: Pre-pro-defensins are cleaved to remove the signal peptide (Gallus gallus)


name: DCD peptide binds bacterial membrane phospholipids (Homo sapiens)


name: Trypsin cleaves REG3A or REG3G to generate REG3A,G(38-175) (Homo sapiens)


name: PI3 binds the bacterial surface (Homo sapiens)


name: REG3A oligomerize to form a pore complex (Homo sapiens)


name: BPI binds LPS on the bacterial surface (Homo sapiens)


name: DCD forms oligomeric complex (Homo sapiens)


name: INTL1 binds bacterial glycans (Homo sapiens)


name: PGLYRP2 binds bacterial peptidoglycan (Homo sapiens)


name: PGLYRP2 hydrolyzes bacterial peptidoglycan (Homo sapiens)


name: Cathelicidin LL-37 binds to bacterial cell wall (Homo sapiens)


name: HTN1,HTN3 or HTN5 binds the bacterial anionic surface  (Homo sapiens)


name: DCD is processed into DCD(63-110) (Homo sapiens)


name: RNASEs bind bacterial LPS, PGN (Homo sapiens)


name: CHGA-derived peptide binds the bacterial cell surface (Homo sapiens)


name: DCD(63-110) is processed to DCD(63-109) (Homo sapiens)


name: REG3A binds bacterial phospholipids (Homo sapiens)


name: LYZ binds bacterial peptidoglycan (Homo sapiens)


name: GNLY is transferred to the phagosome (Homo sapiens)


name: GNLY binds the bacterial cell surface (Homo sapiens)


name: PRTN3 cleaves CAMP(31-170) to generate CAMP(134-170) (Homo sapiens)


name: PGLYRP3,4 binds bacterial peptidoglycan (Homo sapiens)


name: RNASEs bind bacterial phospholipids (Homo sapiens)


name: EPPIN protein complex binds bacteria (Homo sapiens)


name: PLA2G2A binds bacterial phospholipids (Homo sapiens)


name: PGLYRP1 binds bacterial peptidoglycan (Homo sapiens)


name: REG3A,REG3G binds bacterial peptidoglycan (Homo sapiens)


name: LYZ hydrolyzes peptidoglycans in the bacterial cell wall (Homo sapiens)


name: HTN5, (HTN1, HTN3) binds fungal SSA1/SSA2 (Homo sapiens)


name: ELANE, CTSG or PRTN3 binds bacteria (Homo sapiens)


name: GNLY binds the bacterial cell surface in the phagosome (Homo sapiens)


name: Antimicrobial peptides (Rattus norvegicus)


name: INTL1 binds bacterial glycans (Rattus norvegicus)


name: PGLYRP2 hydrolyzes bacterial peptidoglycan (Rattus norvegicus)


name: PGLYRP2 binds bacterial peptidoglycan (Rattus norvegicus)


name: LYZ hydrolyzes peptidoglycans in the bacterial cell wall (Rattus norvegicus)


name: LYZ binds bacterial peptidoglycan (Rattus norvegicus)


name: REG3A,REG3G binds bacterial peptidoglycan (Rattus norvegicus)


name: EPPIN protein complex binds bacteria (Rattus norvegicus)


name: Trypsin cleaves REG3A or REG3G to generate REG3A,G(38-175) (Rattus norvegicus)


name: REG3A binds bacterial phospholipids (Rattus norvegicus)


name: PRTN3 cleaves CAMP(31-170) to generate CAMP(134-170) (Rattus norvegicus)


name: CHGA-derived peptide binds the bacterial cell surface (Rattus norvegicus)


name: PLA2G2A binds bacterial phospholipids (Rattus norvegicus)


name: LEAP2 binds bacteria (Rattus norvegicus)


name: RNASEs bind bacterial phospholipids (Rattus norvegicus)


name: ELANE, CTSG or PRTN3 binds bacteria (Rattus norvegicus)


name: RNASEs bind bacterial LPS, PGN (Rattus norvegicus)


name: PGLYRP3,4 binds bacterial peptidoglycan (Rattus norvegicus)


name: BPI binds LPS on the bacterial surface (Rattus norvegicus)


name: Cathelicidin LL-37 binds to bacterial cell wall (Rattus norvegicus)


name: PGLYRP1 binds bacterial peptidoglycan (Rattus norvegicus)


name: REG3A oligomerize to form a pore complex (Rattus norvegicus)


name: HTN1,HTN3 or HTN5 binds the bacterial anionic surface  (Rattus norvegicus)


name: Antimicrobial peptides (Canis familiaris)


name: REG3A oligomerize to form a pore complex (Canis familiaris)


name: GNLY binds the bacterial cell surface in the phagosome (Canis familiaris)


name: BPI binds LPS on the bacterial surface (Canis familiaris)


name: GNLY binds the bacterial cell surface (Canis familiaris)


name: Trypsin cleaves REG3A or REG3G to generate REG3A,G(38-175) (Canis familiaris)


name: Cathelicidin LL-37 binds to bacterial cell wall (Canis familiaris)


name: REG3A binds bacterial phospholipids (Canis familiaris)


name: PGLYRP2 binds bacterial peptidoglycan (Canis familiaris)


name: PI3 binds the bacterial surface (Canis familiaris)


name: PGLYRP2 hydrolyzes bacterial peptidoglycan (Canis familiaris)


name: ELANE, CTSG or PRTN3 binds bacteria (Canis familiaris)


name: REG3A,REG3G binds bacterial peptidoglycan (Canis familiaris)


name: PGLYRP1 binds bacterial peptidoglycan (Canis familiaris)


name: CHGA-derived peptide binds the bacterial cell surface (Canis familiaris)


name: LYZ hydrolyzes peptidoglycans in the bacterial cell wall (Canis familiaris)


name: GNLY is transferred to the phagosome (Canis familiaris)


name: LYZ binds bacterial peptidoglycan (Canis familiaris)


name: GNLY is transferred to the phagosome (Bos taurus)


name: REG3A oligomerize to form a pore complex (Bos taurus)


name: PI3 binds the bacterial surface (Bos taurus)


name: GNLY binds the bacterial cell surface in the phagosome (Bos taurus)


name: PGLYRP2 hydrolyzes bacterial peptidoglycan (Bos taurus)


name: PGLYRP1 binds bacterial peptidoglycan (Bos taurus)


name: BPI binds LPS on the bacterial surface (Bos taurus)


name: HTN1,HTN3 or HTN5 binds the bacterial anionic surface  (Bos taurus)


name: REG3A binds bacterial phospholipids (Bos taurus)


name: Trypsin cleaves REG3A or REG3G to generate REG3A,G(38-175) (Bos taurus)


name: PGLYRP2 binds bacterial peptidoglycan (Bos taurus)


name: REG3A,REG3G binds bacterial peptidoglycan (Bos taurus)


name: ELANE, CTSG or PRTN3 binds bacteria (Bos taurus)


name: PLA2G2A binds bacterial phospholipids (Bos taurus)


name: Cathelicidin LL-37 binds to bacterial cell wall (Bos taurus)


name: RNASEs bind bacterial phospholipids (Bos taurus)


name: CHGA-derived peptide binds the bacterial cell surface (Bos taurus)


name: INTL1 binds bacterial glycans (Bos taurus)


name: RNASEs bind bacterial LPS, PGN (Bos taurus)


name: LYZ binds bacterial peptidoglycan (Bos taurus)


name: PRTN3 cleaves CAMP(31-170) to generate CAMP(134-170) (Bos taurus)


name: PGLYRP3,4 binds bacterial peptidoglycan (Bos taurus)


name: GNLY binds the bacterial cell surface (Bos taurus)


name: LYZ hydrolyzes peptidoglycans in the bacterial cell wall (Bos taurus)


name: EPPIN protein complex binds bacteria (Bos taurus)


name: REG3A binds bacterial phospholipids (Sus scrofa)


name: EPPIN protein complex binds bacteria (Sus scrofa)


name: LYZ hydrolyzes peptidoglycans in the bacterial cell wall (Sus scrofa)


name: ELANE, CTSG or PRTN3 binds bacteria (Sus scrofa)


name: REG3A,REG3G binds bacterial peptidoglycan (Sus scrofa)


name: PGLYRP2 hydrolyzes bacterial peptidoglycan (Sus scrofa)


name: PGLYRP2 binds bacterial peptidoglycan (Sus scrofa)


name: PI3 binds the bacterial surface (Sus scrofa)


name: PRTN3 cleaves CAMP(31-170) to generate CAMP(134-170) (Sus scrofa)


name: RNASEs bind bacterial phospholipids (Sus scrofa)


name: PGLYRP1 binds bacterial peptidoglycan (Sus scrofa)


name: PLA2G2A binds bacterial phospholipids (Sus scrofa)


name: GNLY is transferred to the phagosome (Sus scrofa)


name: GNLY binds the bacterial cell surface in the phagosome (Sus scrofa)


name: RNASEs bind bacterial LPS, PGN (Sus scrofa)


name: INTL1 binds bacterial glycans (Sus scrofa)


name: REG3A oligomerize to form a pore complex (Sus scrofa)


name: BPI binds LPS on the bacterial surface (Sus scrofa)


name: Cathelicidin LL-37 binds to bacterial cell wall (Sus scrofa)


name: GNLY binds the bacterial cell surface (Sus scrofa)


name: CHGA-derived peptide binds the bacterial cell surface (Sus scrofa)


name: PGLYRP3,4 binds bacterial peptidoglycan (Sus scrofa)


name: Trypsin cleaves REG3A or REG3G to generate REG3A,G(38-175) (Sus scrofa)


name: LYZ binds bacterial peptidoglycan (Sus scrofa)


name: INTL1 binds bacterial glycans (Danio rerio)


name: RNASEs bind bacterial phospholipids (Danio rerio)


name: PGLYRP1 binds bacterial peptidoglycan (Danio rerio)


name: PGLYRP2 binds bacterial peptidoglycan (Danio rerio)


name: PGLYRP2 hydrolyzes bacterial peptidoglycan (Danio rerio)


name: GNLY binds the bacterial cell surface (Danio rerio)


name: GNLY binds the bacterial cell surface in the phagosome (Danio rerio)


name: RNASEs bind bacterial LPS, PGN (Danio rerio)


name: LYZ hydrolyzes peptidoglycans in the bacterial cell wall (Danio rerio)


name: GNLY is transferred to the phagosome (Danio rerio)


name: PGLYRP3,4 binds bacterial peptidoglycan (Danio rerio)


name: LYZ binds bacterial peptidoglycan (Danio rerio)


name: Antimicrobial peptides (Xenopus tropicalis)


name: BPIF binds bacteria (Xenopus tropicalis)


name: ELANE, CTSG or PRTN3 binds bacteria (Xenopus tropicalis)


name: PGLYRP1 binds bacterial peptidoglycan (Xenopus tropicalis)


name: PGLYRP3,4 binds bacterial peptidoglycan (Xenopus tropicalis)


name: LYZ hydrolyzes peptidoglycans in the bacterial cell wall (Xenopus tropicalis)


name: REG3A,REG3G binds bacterial peptidoglycan (Xenopus tropicalis)


name: LYZ binds bacterial peptidoglycan (Xenopus tropicalis)


name: REG3A binds bacterial phospholipids (Xenopus tropicalis)


name: Trypsin cleaves REG3A or REG3G to generate REG3A,G(38-175) (Xenopus tropicalis)


name: PLA2G2A binds bacterial phospholipids (Xenopus tropicalis)


name: CHGA-derived peptide binds the bacterial cell surface (Xenopus tropicalis)


name: INTL1 binds bacterial glycans (Xenopus tropicalis)


name: REG3A oligomerize to form a pore complex (Xenopus tropicalis)


name: PGLYRP2 binds bacterial peptidoglycan (Xenopus tropicalis)


name: BPI binds LPS on the bacterial surface (Xenopus tropicalis)


name: PGLYRP2 hydrolyzes bacterial peptidoglycan (Xenopus tropicalis)


name: PLA2G2A binds bacterial phospholipids (Gallus gallus)


name: ELANE, CTSG or PRTN3 binds bacteria (Gallus gallus)


name: GNLY is transferred to the phagosome (Gallus gallus)


name: PGLYRP2 hydrolyzes bacterial peptidoglycan (Gallus gallus)


name: Cathelicidin LL-37 binds to bacterial cell wall (Gallus gallus)


name: PGLYRP2 binds bacterial peptidoglycan (Gallus gallus)


name: CHGA-derived peptide binds the bacterial cell surface (Gallus gallus)


name: RNASEs bind bacterial phospholipids (Gallus gallus)


name: RNASEs bind bacterial LPS, PGN (Gallus gallus)


name: GNLY binds the bacterial cell surface (Gallus gallus)


name: LYZ hydrolyzes peptidoglycans in the bacterial cell wall (Gallus gallus)


name: BPI binds LPS on the bacterial surface (Gallus gallus)


name: LYZ binds bacterial peptidoglycan (Gallus gallus)


name: GNLY binds the bacterial cell surface in the phagosome (Gallus gallus)


name: Antimicrobial peptides (Drosophila melanogaster)


name: PGLYRP2 binds bacterial peptidoglycan (Drosophila melanogaster)


name: PGLYRP1 binds bacterial peptidoglycan (Drosophila melanogaster)


name: LYZ hydrolyzes peptidoglycans in the bacterial cell wall (Drosophila melanogaster)


name: PGLYRP2 hydrolyzes bacterial peptidoglycan (Drosophila melanogaster)


name: PLA2G2A binds bacterial phospholipids (Drosophila melanogaster)


name: REG3A,REG3G binds bacterial peptidoglycan (Drosophila melanogaster)


name: PGLYRP3,4 binds bacterial peptidoglycan (Drosophila melanogaster)


name: REG3A oligomerize to form a pore complex (Drosophila melanogaster)


name: LYZ binds bacterial peptidoglycan (Drosophila melanogaster)


name: REG3A binds bacterial phospholipids (Drosophila melanogaster)


name: Antimicrobial peptides (Caenorhabditis elegans)


name: REG3A binds bacterial phospholipids (Caenorhabditis elegans)


name: REG3A,REG3G binds bacterial peptidoglycan (Caenorhabditis elegans)


name: REG3A oligomerize to form a pore complex (Caenorhabditis elegans)


name: BPI binds LPS on the bacterial surface (Caenorhabditis elegans)


name: PLA2G2A binds bacterial phospholipids (Caenorhabditis elegans)


name: Antimicrobial peptides (Dictyostelium discoideum)


name: LYZ binds bacterial peptidoglycan (Dictyostelium discoideum)


name: LYZ hydrolyzes peptidoglycans in the bacterial cell wall (Dictyostelium discoideum)


name: BPI binds LPS on the bacterial surface (Dictyostelium discoideum)


name: ROS and RNS production in phagocytes (Mus musculus)


name: Intraphagosomal pH is lowered to 5 by V-ATPase (Mus musculus)


name: Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) (Mus musculus)


name: NOX2 generates superoxide anion from oxygen (Mus musculus)


name: Events associated with phagocytolytic activity of PMN cells (Mus musculus)


name: Myeloperoxidase (MPO) catalyzes oxidation of nitrite to nitrogen dioxide (Mus musculus)


name: Myeloperoxidase (MPO) binds to the bacterial cell surface (Mus musculus)


name: Membrane-bound myeloperoxidase (MPO) produces hypochlorous acid (HOCl) (Mus musculus)


name: Myeloperoxidase (MPO) produces hypochlorous acid (HOCl) (Mus musculus)


name: Lactoperoxidase (LPO) produces OSCN- (Mus musculus)


name: Events associated with phagocytolytic activity of PMN cells (Homo sapiens)


name: HOCl-induced glycosaminoglycan fragmentation (Homo sapiens)


name: Hypochlorous acid (HOCL) oxidizes Cys residues to form Cys-sulfenyl chloride (Homo sapiens)


name: Myeloperoxidase (MPO) binds to the bacterial cell surface (Homo sapiens)


name: Cys-sulfenyl chloride is converted to Cys-sulfenic acid (Homo sapiens)


name: OSCN- reacts with Cys residues (Homo sapiens)


name: Hypochlorous acid (HOCL) reacts with Lys-monochloramine (Homo sapiens)


name: Myeloperoxidase (MPO) catalyzes oxidation of nitrite to nitrogen dioxide (Homo sapiens)


name: Hypochlorous acid and nitrite react to nitryl chloride (NO2Cl) (Homo sapiens)


name: Chloride ion and N-acyl group react to chloramide (Homo sapiens)


name: Lactoperoxidase (LPO) produces OSCN- (Homo sapiens)


name: Hypochlorous acid (HOCl) reacts with unsaturated lipid to form lipid chlorohydrins (Homo sapiens)


name: Hypochlorous acid (HOCL) reacts with Lys residue to form Lys-monochloramine (Homo sapiens)


name: Myeloperoxidase (MPO) produces hypochlorous acid (HOCl) (Homo sapiens)


name: Membrane-bound myeloperoxidase (MPO) produces hypochlorous acid (HOCl) (Homo sapiens)


name: ROS and RNS production in phagocytes (Homo sapiens)


name: Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) (Homo sapiens)


name: NOX2 generates superoxide anion from oxygen (Homo sapiens)


name: Protonation of superoxide (Homo sapiens)


name: Superoxide anion dismutates to H2O2 (Homo sapiens)


name: Nitric oxide diffuses into the phagosome (Homo sapiens)


name: Hydrogen peroxide and Fe2+ react to hydroxyl, hydroxide and Fe3+ (Homo sapiens)


name: Superoxide anion reacts with Fe-S cluster (Homo sapiens)


name: H2O2 oxidizes Cys residues to form Cys-sulfenic acid (Homo sapiens)


name: Nitric oxide enters the bacterium (Homo sapiens)


name: Hydroperoxyl enters the bacterium (Homo sapiens)


name: Hydroxyl-initiated lipid peroxidation (Homo sapiens)


name: Peroxynitrite oxidizes Peptide-Methionine residues (Homo sapiens)


name: Peroxynitrite oxidizes Cys residues (Homo sapiens)


name: Hydroxyl radical reacts with the base and sugar moiety of DNA (Homo sapiens)


name: Nitric oxide oxidizes to nitrosyl ion (Homo sapiens)


name: Glutathione scavenges nitrosyl (Homo sapiens)


name: N2O3 diffuses to phagosome (Homo sapiens)


name: Intraphagosomal pH is lowered to 5 by V-ATPase (Homo sapiens)


name: Superoxide and nitric oxide react to peroxynitrite in the phagosome (Homo sapiens)


name: S-nitrosylation of cysteine residues in proteins by N2O3 (Homo sapiens)


name: Peroxynitrite enters the bacterium (Homo sapiens)


name: Nitric oxide and O2 react to NO2 (Homo sapiens)


name: Hydrogen peroxide enters the bacterium (Homo sapiens)


name: Peroxynitrite and carbon dioxide react to nitrosoperoxycarbonate (Homo sapiens)


name: Nitrite ion and HNO2 form a conjugated acid-base pair (Homo sapiens)


name: Tolerance of reactive oxygen produced by macrophages (Homo sapiens)


name: AhpC reduces peroxidated lipids (Homo sapiens)


name: SodB reduces superoxide to H2O2 (Homo sapiens)


protein-transporting ATPase activity

description: Primary active carrier-mediated transport of a protein across a membrane, driven by the hydrolysis of the diphosphate bond of inorganic pyrophosphate, ATP, or another nucleoside triphosphate. The transport protein may or may not be transiently phosphorylated, but the substrate is not phosphorylated.


name: H2O2 gets scavenged by unsaturated lipid (Homo sapiens)


name: SodC reduces superoxide to H2O2 (Homo sapiens)


name: Mtb iron assimilation by chelation (Homo sapiens)


name: Iron is reduced and separates from mycobactin (Homo sapiens)


name: LTF:2xCO3(2-) dissociates from Carbocymycobactin:Fe3+ (Homo sapiens)


name: Loaded mycobactin gets imported (Homo sapiens)


name: Carboxymycobactin and mycobactin exchange their iron load (Homo sapiens)


name: Carbocymycobactin binds Fe3+ from LTF:2xFe3+:2xCO3(2-) (Homo sapiens)


name: Carboxymycobactin binds LTF:2xFe3+:2xCO3(2-) (Homo sapiens)


name: Carboxymycobactin gets secreted (Homo sapiens)


name: Tolerance by Mtb to nitric oxide produced by macrophages (Homo sapiens)


name: Nitrogen dioxide is reduced to NO by F420 (Homo sapiens)


name: Peroxynitrite is reduced to nitrite by AhpC (Homo sapiens)


name: Nitrosoglutathione gets cleaved to Cys(NO)-Gly (Homo sapiens)


name: MsrA/B reduces peptide-methionine S/R-sulfoxides (Homo sapiens)


name: peptide transmembrane transporter activity

description: Enables the transfer of a peptide from one side of a membrane to the other.


name: MscR reduces nitrosomycothiol to ammonia (Homo sapiens)


name: Peroxynitrite is reduced by AhpE (Homo sapiens)


name: Peroxynitrite is reduced to nitrite by Tpx (Homo sapiens)


name: Nitric oxide is oxidized to nitrate (Homo sapiens)


name: Mycothiol scavenges nitrosyl (Homo sapiens)


cell redox homeostasis

category: biolink:BiologicalProcess biolink:Occurrent biolink:OntologyClass biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: Any process that maintains the redox environment of a cell or compartment within a cell.


name: lpdC dimer reactivates dlaT (Homo sapiens)


name: RHO GTPases Activate NADPH Oxidases (Homo sapiens)


name: MAPK1 or MAPK3 phosphorylates NCF1 at Ser345 (Homo sapiens)


name: Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP (Homo sapiens)


name: NADPH oxidase 2 (NOX2) complex binds RAC1 (Homo sapiens)


name: RAC1:GTP binds NOX3 complex (Homo sapiens)


name: RAC2:GTP binds NOX2 complex (Homo sapiens)


name: NOX3 complex:RAC1:GTP generates superoxide from oxygen (Homo sapiens)


name: MAPK11 or MAPK14 phosphorylates NCF1 at Ser345 (Homo sapiens)


name: S100A8:S100A9:AA:Ca(2+) binds NOX2 complex (Homo sapiens)


name: NADPH oxidase 2 generates superoxide from oxygen (Homo sapiens)


name: NOX1 complex:RAC1:GTP generates superoxide from oxygen (Homo sapiens)


name: PIK3C3:PIK3R4 phosphorylates PI to PI3P (Homo sapiens)


name: RAC1:GTP binds NOX1 complex (Homo sapiens)


name: AAMP gene expression is positively regulated by VEGF (Homo sapiens)


name: Neurophilin interactions with VEGF and VEGFR (Homo sapiens)


name: NRP-2 associates with VEGFR1 forming complexes on  cell surface (Homo sapiens)


name: NRP-1 forms a ternary complex with VEGF165 and VEGFR1 (Homo sapiens)


name: Neurophilin interactions with VEGF and VEGFR (Mus musculus)


name: NRP-1 forms a ternary complex with VEGF165 and VEGFR1 (Mus musculus)


name: NRP-2 associates with VEGFR1 forming complexes on  cell surface (Mus musculus)


name: Neurophilin interactions with VEGF and VEGFR (Rattus norvegicus)


name: NRP-2 associates with VEGFR1 forming complexes on  cell surface (Rattus norvegicus)


name: NRP-1 forms a ternary complex with VEGF165 and VEGFR1 (Rattus norvegicus)


name: Neurophilin interactions with VEGF and VEGFR (Canis familiaris)


name: NRP-2 associates with VEGFR1 forming complexes on  cell surface (Canis familiaris)


name: NRP-1 forms a ternary complex with VEGF165 and VEGFR1 (Canis familiaris)


name: Neurophilin interactions with VEGF and VEGFR (Bos taurus)


name: NRP-2 associates with VEGFR1 forming complexes on  cell surface (Bos taurus)


name: NRP-1 forms a ternary complex with VEGF165 and VEGFR1 (Bos taurus)


name: Neurophilin interactions with VEGF and VEGFR (Sus scrofa)


name: NRP-2 associates with VEGFR1 forming complexes on  cell surface (Sus scrofa)


name: NRP-1 forms a ternary complex with VEGF165 and VEGFR1 (Sus scrofa)


name: Neurophilin interactions with VEGF and VEGFR (Danio rerio)


name: NRP-1 forms a ternary complex with VEGF165 and VEGFR1 (Danio rerio)


name: Neurophilin interactions with VEGF and VEGFR (Xenopus tropicalis)


name: NRP-1 forms a ternary complex with VEGF165 and VEGFR1 (Xenopus tropicalis)


name: Neurophilin interactions with VEGF and VEGFR (Gallus gallus)


name: NRP-1 forms a ternary complex with VEGF165 and VEGFR1 (Gallus gallus)


name: NRP-2 associates with VEGFR1 forming complexes on  cell surface (Gallus gallus)


name: RHOA:GTP:Mg2+ binds ROCK1,ROCK2 (Homo sapiens)


name: SRC1-1 binds SH2D2A and is recruited to VEGFR2 (Homo sapiens)


name: VAV exchanges GTP for GDP on RAC1, activating it (Homo sapiens)


name: ROCK1,ROCK2 are activated (Homo sapiens)


name: HSP90AA1 binds p-6Y-VEGFR2 (Homo sapiens)


name: SRC-1 phosphorylates p-Y397-PTK2 (Homo sapiens)


name: AXL autophosphorylates on Y779 and Y821 (Homo sapiens)


name: p-VAV family:PIP3 binds RAC1:GDP (Homo sapiens)


name: p-MAPK2/3 phosphorylates HSP27 (Homo sapiens)


name: PTK2 binds p-S-SHB and is recruited to p-6Y-VEGFR2 (Homo sapiens)


name: PTK2 and SRC-1 phosphorylate PXN on Y31 and Y118 (Homo sapiens)


name: p38 MAPK activation by VEGFR (Homo sapiens)


name: SRC-1 phosphorylates PTK2-beta (Homo sapiens)


name: VEGF induces CDC42 activation by unknown mechanism (Homo sapiens)


name: PTK2/SRC-1 phosphorylates BCAR1 (Homo sapiens)


name: Active ROCK1,ROCK2 phosphorylates p-5Y-PTK2 on S732 (Homo sapiens)


name: p-6Y-VEGFR2 binds SHC-transforming protein 2 (Homo sapiens)


name: CRK binds BCAR1 and or PXN (Homo sapiens)


name: PI(3,4,5)P3 binds VAV1,2,3 (Homo sapiens)


name: Src kinases phosphorylate VAV (Homo sapiens)


name: VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K phosphorylates PIP2 to PIP3 (Homo sapiens)


name: Integrin alphaVbeta3 binds p-6Y-VEGFR2 (Homo sapiens)


name: VEGFR2 autophosphorylates (Homo sapiens)


name: DOCK180:ELMO exchanges GTP for GDP, activating RAC1 (Homo sapiens)


name: PTK2beta binds alphaVbeta3 (Homo sapiens)


name: VEGFA-165 dimer binds VEGFR2 dimer (Homo sapiens)


name: VEGFA-165 dimer binds VEGFA inhibitors (Homo sapiens)


name: p-Y420-FYN is phosphorylated on S21 (Homo sapiens)


name: p-Y402-PTK2B phosphorylates p-5Y,S732-PTK2 on Y407 (Homo sapiens)


name: VEGFR2 mediated cell proliferation (Homo sapiens)


name: PLCG1 disassociates from VEGFR2 and translocate to PM (Homo sapiens)


name: PKC phosphorylates sphingosine kinase 1 (Homo sapiens)


name: p-SPHK1 phosphorylates sphingosine to sphingosine 1-phosphate (Homo sapiens)


name: DAG and Ca+2 bind to PKC and tether it to membrane (Homo sapiens)


name: VEGFR2 mediated cell proliferation (Mus musculus)


name: p-SPHK1 phosphorylates sphingosine to sphingosine 1-phosphate (Mus musculus)


name: PLCG1 disassociates from VEGFR2 and translocate to PM (Mus musculus)


name: PKC phosphorylates sphingosine kinase 1 (Mus musculus)


name: DAG and Ca+2 bind to PKC and tether it to membrane (Mus musculus)


name: VEGFR2 mediated cell proliferation (Rattus norvegicus)


name: PKC phosphorylates sphingosine kinase 1 (Rattus norvegicus)


name: p-SPHK1 phosphorylates sphingosine to sphingosine 1-phosphate (Rattus norvegicus)


name: DAG and Ca+2 bind to PKC and tether it to membrane (Rattus norvegicus)


name: SFKs phosphorylate PLCG1 (Rattus norvegicus)


name: p-6Y-VEGFR2 binds PLCG1 (Rattus norvegicus)


name: PLCG1 disassociates from VEGFR2 and translocate to PM (Rattus norvegicus)


name: PDK1 phosphorylates PKC (Rattus norvegicus)


name: PKC autophosphorylates (Rattus norvegicus)


name: VEGFR2 mediated cell proliferation (Canis familiaris)


name: PLCG1 disassociates from VEGFR2 and translocate to PM (Canis familiaris)


name: PKC autophosphorylates (Canis familiaris)


name: p-SPHK1 phosphorylates sphingosine to sphingosine 1-phosphate (Canis familiaris)


name: PDK1 phosphorylates PKC (Canis familiaris)


name: SFKs phosphorylate PLCG1 (Canis familiaris)


name: p-6Y-VEGFR2 binds PLCG1 (Canis familiaris)


name: PKC phosphorylates sphingosine kinase 1 (Canis familiaris)


name: DAG and Ca+2 bind to PKC and tether it to membrane (Canis familiaris)


name: VEGFR2 mediated cell proliferation (Bos taurus)


name: PKC phosphorylates sphingosine kinase 1 (Bos taurus)


name: DAG and Ca+2 bind to PKC and tether it to membrane (Bos taurus)


name: PLCG1 disassociates from VEGFR2 and translocate to PM (Bos taurus)


name: p-SPHK1 phosphorylates sphingosine to sphingosine 1-phosphate (Bos taurus)


name: VEGFR2 mediated cell proliferation (Sus scrofa)


name: PLCG1 disassociates from VEGFR2 and translocate to PM (Sus scrofa)


name: PKC phosphorylates sphingosine kinase 1 (Sus scrofa)


name: DAG and Ca+2 bind to PKC and tether it to membrane (Sus scrofa)


name: p-SPHK1 phosphorylates sphingosine to sphingosine 1-phosphate (Sus scrofa)


name: VEGFR2 mediated cell proliferation (Danio rerio)


name: DAG and Ca+2 bind to PKC and tether it to membrane (Danio rerio)


name: PLCG1 disassociates from VEGFR2 and translocate to PM (Danio rerio)


name: VEGFR2 mediated cell proliferation (Xenopus tropicalis)


name: PLCG1 disassociates from VEGFR2 and translocate to PM (Xenopus tropicalis)


name: p-6Y-VEGFR2 binds PLCG1 (Xenopus tropicalis)


name: DAG and Ca+2 bind to PKC and tether it to membrane (Xenopus tropicalis)


name: PKC autophosphorylates (Xenopus tropicalis)


name: PDK1 phosphorylates PKC (Xenopus tropicalis)


name: VEGFR2 mediated cell proliferation (Gallus gallus)


name: p-SPHK1 phosphorylates sphingosine to sphingosine 1-phosphate (Gallus gallus)


name: PLCG1 disassociates from VEGFR2 and translocate to PM (Gallus gallus)


name: DAG and Ca+2 bind to PKC and tether it to membrane (Gallus gallus)


name: SFKs phosphorylate PLCG1 (Gallus gallus)


name: PKC phosphorylates sphingosine kinase 1 (Gallus gallus)


name: VEGFR2 mediated cell proliferation (Drosophila melanogaster)


name: PDK1 phosphorylates PKC (Drosophila melanogaster)


name: p-SPHK1 phosphorylates sphingosine to sphingosine 1-phosphate (Drosophila melanogaster)


name: PKC phosphorylates sphingosine kinase 1 (Drosophila melanogaster)


name: PKC autophosphorylates (Drosophila melanogaster)


name: DAG and Ca+2 bind to PKC and tether it to membrane (Drosophila melanogaster)


name: VEGFR2 mediated cell proliferation (Caenorhabditis elegans)


name: PDK1 phosphorylates PKC (Caenorhabditis elegans)


name: PKC autophosphorylates (Caenorhabditis elegans)


name: PKC phosphorylates sphingosine kinase 1 (Caenorhabditis elegans)


name: DAG and Ca+2 bind to PKC and tether it to membrane (Caenorhabditis elegans)


name: VEGFR2 mediated cell proliferation (Dictyostelium discoideum)


name: PKC autophosphorylates (Dictyostelium discoideum)


name: PDK1 phosphorylates PKC (Dictyostelium discoideum)


name: PKC phosphorylates sphingosine kinase 1 (Dictyostelium discoideum)


name: DAG and Ca+2 bind to PKC and tether it to membrane (Dictyostelium discoideum)


name: VEGFR2 mediated cell proliferation (Schizosaccharomyces pombe)


name: PDK1 phosphorylates PKC (Schizosaccharomyces pombe)


name: PKC autophosphorylates (Schizosaccharomyces pombe)


name: PKC phosphorylates sphingosine kinase 1 (Schizosaccharomyces pombe)


name: DAG and Ca+2 bind to PKC and tether it to membrane (Schizosaccharomyces pombe)


name: VEGFR2 mediated cell proliferation (Saccharomyces cerevisiae)


name: PKC autophosphorylates (Saccharomyces cerevisiae)


name: PDK1 phosphorylates PKC (Saccharomyces cerevisiae)


name: PKC phosphorylates sphingosine kinase 1 (Saccharomyces cerevisiae)


name: DAG and Ca+2 bind to PKC and tether it to membrane (Saccharomyces cerevisiae)


name: VEGFR2 mediated vascular permeability (Homo sapiens)


name: PAK1-3 phosphorylates VE-cadherin (Homo sapiens)


name: PAK1-3 dimer disassociates (Homo sapiens)


name: PAK1-3 autophosphorylates (Homo sapiens)


name: VEGFR2 mediated vascular permeability (Mus musculus)


name: PAK1-3 dimer disassociates (Mus musculus)


name: PAK1-3 autophosphorylates (Mus musculus)


name: PAK1-3 phosphorylates VE-cadherin (Mus musculus)


name: VEGFR2 mediated vascular permeability (Rattus norvegicus)


name: PAK1-3 phosphorylates VE-cadherin (Rattus norvegicus)


name: PAK1-3 dimer disassociates (Rattus norvegicus)


name: PAK1-3 autophosphorylates (Rattus norvegicus)


name: VEGFR2 mediated vascular permeability (Canis familiaris)


name: PAK1-3 autophosphorylates (Canis familiaris)


name: PAK1-3 phosphorylates VE-cadherin (Canis familiaris)


name: PAK1-3 dimer disassociates (Canis familiaris)


name: VEGFR2 mediated vascular permeability (Bos taurus)


name: PAK1-3 phosphorylates VE-cadherin (Bos taurus)


name: VEGFR2 mediated vascular permeability (Sus scrofa)


name: PAK1-3 phosphorylates VE-cadherin (Sus scrofa)


name: VEGFR2 mediated vascular permeability (Danio rerio)


name: PAK1-3 phosphorylates VE-cadherin (Danio rerio)


name: VEGFR2 mediated vascular permeability (Xenopus tropicalis)


name: PAK1-3 dimer disassociates (Xenopus tropicalis)


name: PAK1-3 phosphorylates VE-cadherin (Xenopus tropicalis)


name: PAK1-3 autophosphorylates (Xenopus tropicalis)


name: VEGFR2 mediated vascular permeability (Gallus gallus)


name: PAK1-3 phosphorylates VE-cadherin (Gallus gallus)


name: PAK1-3 autophosphorylates (Gallus gallus)


name: PAK1-3 dimer disassociates (Gallus gallus)


name: VEGFR2 mediated vascular permeability (Drosophila melanogaster)


name: PAK1-3 phosphorylates VE-cadherin (Drosophila melanogaster)


name: PAK1-3 dimer disassociates (Drosophila melanogaster)


name: RAC1 binds PAK1-3 (Drosophila melanogaster)


name: PAK1-3 autophosphorylates (Drosophila melanogaster)


name: VEGFR2 mediated vascular permeability (Caenorhabditis elegans)


name: PAK1-3 dimer disassociates (Caenorhabditis elegans)


name: PAK1-3 autophosphorylates (Caenorhabditis elegans)


name: PAK1-3 phosphorylates VE-cadherin (Caenorhabditis elegans)


name: RAC1 binds PAK1-3 (Caenorhabditis elegans)


name: VEGFR2 mediated vascular permeability (Dictyostelium discoideum)


name: VEGFR2 mediated vascular permeability (Schizosaccharomyces pombe)


name: VEGFR2 mediated vascular permeability (Saccharomyces cerevisiae)


name: VEGFR2 mediated vascular permeability (Plasmodium falciparum)


name: VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K phosphorylates PIP2 to PIP3 (Mus musculus)


name: Src kinases phosphorylate VAV (Mus musculus)


name: AXL autophosphorylates on Y779 and Y821 (Mus musculus)


name: p38 MAPK activation by VEGFR (Mus musculus)


name: p-VAV family:PIP3 binds RAC1:GDP (Mus musculus)


name: ROCK1,ROCK2 are activated (Mus musculus)


name: p-MAPK2/3 phosphorylates HSP27 (Mus musculus)


name: SRC-1 phosphorylates p-Y397-PTK2 (Mus musculus)


name: VEGFA-165 dimer binds VEGFR2 dimer (Mus musculus)


name: HSP90AA1 binds p-6Y-VEGFR2 (Mus musculus)


name: Integrin alphaVbeta3 binds p-6Y-VEGFR2 (Mus musculus)


name: Active ROCK1,ROCK2 phosphorylates p-5Y-PTK2 on S732 (Mus musculus)


name: RHOA:GTP:Mg2+ binds ROCK1,ROCK2 (Mus musculus)


name: CRK binds BCAR1 and or PXN (Mus musculus)


name: DOCK180:ELMO exchanges GTP for GDP, activating RAC1 (Mus musculus)


name: NADPH oxidase 2 generates superoxide from oxygen (Mus musculus)


name: PTK2 and SRC-1 phosphorylate PXN on Y31 and Y118 (Mus musculus)


name: PTK2 binds p-S-SHB and is recruited to p-6Y-VEGFR2 (Mus musculus)


name: PTK2beta binds alphaVbeta3 (Mus musculus)


name: SRC-1 phosphorylates PTK2-beta (Mus musculus)


name: NADPH oxidase 2 (NOX2) complex binds RAC1 (Mus musculus)


name: SRC1-1 binds SH2D2A and is recruited to VEGFR2 (Mus musculus)


name: p-Y420-FYN is phosphorylated on S21 (Mus musculus)


name: VEGFR2 autophosphorylates (Mus musculus)


name: VAV exchanges GTP for GDP on RAC1, activating it (Mus musculus)


name: p-Y402-PTK2B phosphorylates p-5Y,S732-PTK2 on Y407 (Mus musculus)


name: p-6Y-VEGFR2 binds SHC-transforming protein 2 (Mus musculus)


name: VEGFA-165 dimer binds VEGFA inhibitors (Mus musculus)


name: VEGFA-VEGFR2 Pathway (Rattus norvegicus)


name: p-MAPK2/3 phosphorylates HSP27 (Rattus norvegicus)


name: SRC-1 phosphorylates PTK2-beta (Rattus norvegicus)


name: CDC42:GTP binds PAK2 (Rattus norvegicus)


name: ROCK1,ROCK2 are activated (Rattus norvegicus)


name: RHOA:GTP:Mg2+ binds ROCK1,ROCK2 (Rattus norvegicus)


name: HSP90AA1 binds p-6Y-VEGFR2 (Rattus norvegicus)


name: Phosphorylation of SRC-1 (Rattus norvegicus)


name: VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K phosphorylates PIP2 to PIP3 (Rattus norvegicus)


name: NADPH oxidase 2 (NOX2) complex binds RAC1 (Rattus norvegicus)


name: PTK2 autophosphorylates (Rattus norvegicus)


name: FYN autophosphorylates (Rattus norvegicus)


name: Src kinases phosphorylate VAV (Rattus norvegicus)


name: SRC-1 binds p-Y397-PTK2 (Rattus norvegicus)


name: p-6Y-VEGFR2 binds SH2D2A (Rattus norvegicus)


name: SRC1-1 binds SH2D2A and is recruited to VEGFR2 (Rattus norvegicus)


name: VEGFA-165 dimer binds VEGFR2 dimer (Rattus norvegicus)


name: SRC-1 phosphorylates p-Y397-PTK2 (Rattus norvegicus)


name: VEGFA-165 dimer binds VEGFA inhibitors (Rattus norvegicus)


name: p-Y420-FYN is phosphorylated on S21 (Rattus norvegicus)


name: Active ROCK1,ROCK2 phosphorylates p-5Y-PTK2 on S732 (Rattus norvegicus)


name: p-6Y-VEGFR2 binds NCK (Rattus norvegicus)


name: VAV exchanges GTP for GDP on RAC1, activating it (Rattus norvegicus)


name: p-6Y-VEGFR2 binds FYN (Rattus norvegicus)


name: SRC-1 phosphorylates SHB (Rattus norvegicus)


name: Integrin alphaVbeta3 binds p-6Y-VEGFR2 (Rattus norvegicus)


name: p-Y402-PTK2B phosphorylates p-5Y,S732-PTK2 on Y407 (Rattus norvegicus)


name: CRK binds BCAR1 and or PXN (Rattus norvegicus)


name: p-6Y-VEGFR2 binds SHC-transforming protein 2 (Rattus norvegicus)


name: VEGFR2 autophosphorylates (Rattus norvegicus)


name: p-VAV family:PIP3 binds RAC1:GDP (Rattus norvegicus)


name: NADPH oxidase 2 generates superoxide from oxygen (Rattus norvegicus)


name: DOCK180:ELMO exchanges GTP for GDP, activating RAC1 (Rattus norvegicus)


name: FYN phosphorylates PAK2 (Rattus norvegicus)


name: p38 MAPK activation by VEGFR (Rattus norvegicus)


name: PXN binds p-6Y,S732-PTK2 (Rattus norvegicus)


name: PTK2 binds p-S-SHB and is recruited to p-6Y-VEGFR2 (Rattus norvegicus)


name: AXL autophosphorylates on Y779 and Y821 (Rattus norvegicus)


name: PTK2beta binds alphaVbeta3 (Rattus norvegicus)


name: p-6Y-VEGFR2 binds SHB  (Rattus norvegicus)


name: PTK2 and SRC-1 phosphorylate PXN on Y31 and Y118 (Rattus norvegicus)


name: SRC1-1 binds SH2D2A and is recruited to VEGFR2 (Canis familiaris)


name: SRC-1 phosphorylates PTK2-beta (Canis familiaris)


name: NADPH oxidase 2 (NOX2) complex binds RAC1 (Canis familiaris)


name: p-6Y-VEGFR2 binds NCK (Canis familiaris)


name: Integrin alphaVbeta3 binds p-6Y-VEGFR2 (Canis familiaris)


name: VEGFA-165 dimer binds VEGFR2 dimer (Canis familiaris)


name: SRC-1 phosphorylates SHB (Canis familiaris)


name: HSP90AA1 binds p-6Y-VEGFR2 (Canis familiaris)


name: PTK2 autophosphorylates (Canis familiaris)


name: ROCK1,ROCK2 are activated (Canis familiaris)


name: FYN autophosphorylates (Canis familiaris)


name: SRC-1 binds p-Y397-PTK2 (Canis familiaris)


name: VEGFR2 autophosphorylates (Canis familiaris)


name: VEGFA-165 dimer binds VEGFA inhibitors (Canis familiaris)


name: p-Y420-FYN is phosphorylated on S21 (Canis familiaris)


name: p-6Y-VEGFR2 binds SHC-transforming protein 2 (Canis familiaris)


name: SRC-1 phosphorylates p-Y397-PTK2 (Canis familiaris)


name: Active ROCK1,ROCK2 phosphorylates p-5Y-PTK2 on S732 (Canis familiaris)


name: FYN phosphorylates PAK2 (Canis familiaris)


name: p-6Y-VEGFR2 binds FYN (Canis familiaris)


name: PTK2 binds p-S-SHB and is recruited to p-6Y-VEGFR2 (Canis familiaris)


name: VAV exchanges GTP for GDP on RAC1, activating it (Canis familiaris)


name: p-6Y-VEGFR2 binds SHB  (Canis familiaris)


name: p-Y402-PTK2B phosphorylates p-5Y,S732-PTK2 on Y407 (Canis familiaris)


name: DOCK180:ELMO binds CRK (Canis familiaris)


name: CRK binds BCAR1 and or PXN (Canis familiaris)


name: AXL autophosphorylates on Y779 and Y821 (Canis familiaris)


name: Src kinases phosphorylate VAV (Canis familiaris)


name: NADPH oxidase 2 generates superoxide from oxygen (Canis familiaris)


name: Phosphorylation of SRC-1 (Canis familiaris)


name: DOCK180:ELMO exchanges GTP for GDP, activating RAC1 (Canis familiaris)


name: p38 MAPK activation by VEGFR (Canis familiaris)


name: PTK2beta binds alphaVbeta3 (Canis familiaris)


name: RHOA:GTP:Mg2+ binds ROCK1,ROCK2 (Canis familiaris)


name: PTK2 and SRC-1 phosphorylate PXN on Y31 and Y118 (Canis familiaris)


name: p-6Y-VEGFR2 binds SH2D2A (Canis familiaris)


name: p-VAV family:PIP3 binds RAC1:GDP (Canis familiaris)


name: VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K phosphorylates PIP2 to PIP3 (Canis familiaris)


name: PXN binds p-6Y,S732-PTK2 (Canis familiaris)


name: SRC1-1 binds SH2D2A and is recruited to VEGFR2 (Bos taurus)


name: p-MAPK2/3 phosphorylates HSP27 (Bos taurus)


name: Integrin alphaVbeta3 binds p-6Y-VEGFR2 (Bos taurus)


name: VEGFA-165 dimer binds VEGFR2 dimer (Bos taurus)


name: SRC-1 phosphorylates p-Y397-PTK2 (Bos taurus)


name: p-6Y-VEGFR2 binds SHC-transforming protein 2 (Bos taurus)


name: AXL autophosphorylates on Y779 and Y821 (Bos taurus)


name: p38 MAPK activation by VEGFR (Bos taurus)


name: Src kinases phosphorylate VAV (Bos taurus)


name: VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K phosphorylates PIP2 to PIP3 (Bos taurus)


name: PTK2 and SRC-1 phosphorylate PXN on Y31 and Y118 (Bos taurus)


name: SRC-1 phosphorylates PTK2-beta (Bos taurus)


name: RHOA:GTP:Mg2+ binds ROCK1,ROCK2 (Bos taurus)


name: NADPH oxidase 2 (NOX2) complex binds RAC1 (Bos taurus)


name: Active ROCK1,ROCK2 phosphorylates p-5Y-PTK2 on S732 (Bos taurus)


name: VEGFA-165 dimer binds VEGFA inhibitors (Bos taurus)


name: p-Y420-FYN is phosphorylated on S21 (Bos taurus)


name: p-Y402-PTK2B phosphorylates p-5Y,S732-PTK2 on Y407 (Bos taurus)


name: PTK2 binds p-S-SHB and is recruited to p-6Y-VEGFR2 (Bos taurus)


name: VAV exchanges GTP for GDP on RAC1, activating it (Bos taurus)


name: NADPH oxidase 2 generates superoxide from oxygen (Bos taurus)


name: p-VAV family:PIP3 binds RAC1:GDP (Bos taurus)


name: DOCK180:ELMO exchanges GTP for GDP, activating RAC1 (Bos taurus)


name: p38 MAPK activation by VEGFR (Sus scrofa)


name: SRC1-1 binds SH2D2A and is recruited to VEGFR2 (Sus scrofa)


name: Src kinases phosphorylate VAV (Sus scrofa)


name: NADPH oxidase 2 generates superoxide from oxygen (Sus scrofa)


name: DOCK180:ELMO exchanges GTP for GDP, activating RAC1 (Sus scrofa)


name: VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K phosphorylates PIP2 to PIP3 (Sus scrofa)


name: PTK2 and SRC-1 phosphorylate PXN on Y31 and Y118 (Sus scrofa)


name: AXL autophosphorylates on Y779 and Y821 (Sus scrofa)


name: SRC-1 phosphorylates PTK2-beta (Sus scrofa)


name: p-MAPK2/3 phosphorylates HSP27 (Sus scrofa)


name: VEGFA-165 dimer binds VEGFR2 dimer (Sus scrofa)


name: Integrin alphaVbeta3 binds p-6Y-VEGFR2 (Sus scrofa)


name: p-6Y-VEGFR2 binds SHC-transforming protein 2 (Sus scrofa)


name: NADPH oxidase 2 (NOX2) complex binds RAC1 (Sus scrofa)


name: SRC-1 phosphorylates p-Y397-PTK2 (Sus scrofa)


name: Active ROCK1,ROCK2 phosphorylates p-5Y-PTK2 on S732 (Sus scrofa)


name: RHOA:GTP:Mg2+ binds ROCK1,ROCK2 (Sus scrofa)


name: VEGFA-165 dimer binds VEGFA inhibitors (Sus scrofa)


name: p-Y420-FYN is phosphorylated on S21 (Sus scrofa)


name: p-Y402-PTK2B phosphorylates p-5Y,S732-PTK2 on Y407 (Sus scrofa)


name: VAV exchanges GTP for GDP on RAC1, activating it (Sus scrofa)


name: p-VAV family:PIP3 binds RAC1:GDP (Sus scrofa)


name: p-MAPK2/3 phosphorylates HSP27 (Danio rerio)


name: Integrin alphaVbeta3 binds p-6Y-VEGFR2 (Danio rerio)


name: NADPH oxidase 2 (NOX2) complex binds RAC1 (Danio rerio)


name: p-Y420-FYN is phosphorylated on S21 (Danio rerio)


name: RHOA:GTP:Mg2+ binds ROCK1,ROCK2 (Danio rerio)


name: VEGFA-165 dimer binds VEGFA inhibitors (Danio rerio)


name: NADPH oxidase 2 generates superoxide from oxygen (Danio rerio)


name: VEGFA-165 dimer binds VEGFR2 dimer (Danio rerio)


name: p38 MAPK activation by VEGFR (Danio rerio)


name: PTK2beta binds alphaVbeta3 (Danio rerio)


name: VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K phosphorylates PIP2 to PIP3 (Danio rerio)


name: VEGFA-VEGFR2 Pathway (Xenopus tropicalis)


name: p-6Y-VEGFR2 binds SHB  (Xenopus tropicalis)


name: p-Y420-FYN is phosphorylated on S21 (Xenopus tropicalis)


name: VAV exchanges GTP for GDP on RAC1, activating it (Xenopus tropicalis)


name: ROCK1,ROCK2 are activated (Xenopus tropicalis)


name: VEGFA-165 dimer binds VEGFA inhibitors (Xenopus tropicalis)


name: VEGFA-165 dimer binds VEGFR2 dimer (Xenopus tropicalis)


name: FYN phosphorylates PAK2 (Xenopus tropicalis)


name: NADPH oxidase 2 generates superoxide from oxygen (Xenopus tropicalis)


name: DOCK180:ELMO exchanges GTP for GDP, activating RAC1 (Xenopus tropicalis)


name: CDC42:GTP binds PAK2 (Xenopus tropicalis)


name: PTK2 autophosphorylates (Xenopus tropicalis)


name: DOCK180:ELMO binds CRK (Xenopus tropicalis)


name: NADPH oxidase 2 (NOX2) complex binds RAC1 (Xenopus tropicalis)


name: FYN autophosphorylates (Xenopus tropicalis)


name: p-6Y-VEGFR2 binds FYN (Xenopus tropicalis)


name: VEGFR2 autophosphorylates (Xenopus tropicalis)


name: RHOA:GTP:Mg2+ binds ROCK1,ROCK2 (Xenopus tropicalis)


name: p-VAV family:PIP3 binds RAC1:GDP (Xenopus tropicalis)


name: VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K phosphorylates PIP2 to PIP3 (Xenopus tropicalis)


name: Integrin alphaVbeta3 binds p-6Y-VEGFR2 (Xenopus tropicalis)


name: p-6Y-VEGFR2 binds SHC-transforming protein 2 (Xenopus tropicalis)


name: p-6Y-VEGFR2 binds NCK (Xenopus tropicalis)


name: p38 MAPK activation by VEGFR (Xenopus tropicalis)


name: PAK2 autophorylates (Xenopus tropicalis)


name: Active ROCK1,ROCK2 phosphorylates p-5Y-PTK2 on S732 (Gallus gallus)


name: AXL autophosphorylates on Y779 and Y821 (Gallus gallus)


name: HSP90AA1 binds p-6Y-VEGFR2 (Gallus gallus)


name: p-MAPK2/3 phosphorylates HSP27 (Gallus gallus)


name: VEGFA-165 dimer binds VEGFA inhibitors (Gallus gallus)


name: NADPH oxidase 2 (NOX2) complex binds RAC1 (Gallus gallus)


name: p-6Y-VEGFR2 binds SHC-transforming protein 2 (Gallus gallus)


name: RHOA:GTP:Mg2+ binds ROCK1,ROCK2 (Gallus gallus)


name: VEGFR2 autophosphorylates (Gallus gallus)


name: Integrin alphaVbeta3 binds p-6Y-VEGFR2 (Gallus gallus)


name: SRC-1 phosphorylates SHB (Gallus gallus)


name: SRC-1 phosphorylates PTK2-beta (Gallus gallus)


name: VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K phosphorylates PIP2 to PIP3 (Gallus gallus)


name: PTK2beta binds alphaVbeta3 (Gallus gallus)


name: VEGFA-165 dimer binds VEGFR2 dimer (Gallus gallus)


name: PTK2 and SRC-1 phosphorylate PXN on Y31 and Y118 (Gallus gallus)


name: SRC1-1 binds SH2D2A and is recruited to VEGFR2 (Gallus gallus)


name: p38 MAPK activation by VEGFR (Gallus gallus)


name: PXN binds p-6Y,S732-PTK2 (Gallus gallus)


name: NADPH oxidase 2 generates superoxide from oxygen (Gallus gallus)


name: DOCK180:ELMO exchanges GTP for GDP, activating RAC1 (Gallus gallus)


name: Src kinases phosphorylate VAV (Gallus gallus)


name: p-6Y-VEGFR2 binds SH2D2A (Gallus gallus)


name: Phosphorylation of SRC-1 (Gallus gallus)


name: CRK binds BCAR1 and or PXN (Gallus gallus)


name: ROCK1,ROCK2 are activated (Gallus gallus)


name: VAV exchanges GTP for GDP on RAC1, activating it (Gallus gallus)


name: p-Y402-PTK2B phosphorylates p-5Y,S732-PTK2 on Y407 (Gallus gallus)


name: PTK2 binds p-S-SHB and is recruited to p-6Y-VEGFR2 (Gallus gallus)


name: SRC-1 phosphorylates p-Y397-PTK2 (Gallus gallus)


name: p-VAV family:PIP3 binds RAC1:GDP (Gallus gallus)


name: VEGFA-VEGFR2 Pathway (Drosophila melanogaster)


name: DOCK180:ELMO exchanges GTP for GDP, activating RAC1 (Drosophila melanogaster)


name: RHOA:GTP:Mg2+ binds ROCK1,ROCK2 (Drosophila melanogaster)


name: p-MAPK2/3 phosphorylates HSP27 (Drosophila melanogaster)


name: FYN autophosphorylates (Drosophila melanogaster)


name: PAK2 autophorylates (Drosophila melanogaster)


name: FYN phosphorylates PAK2 (Drosophila melanogaster)


name: CDC42:GTP binds PAK2 (Drosophila melanogaster)


name: ROCK1,ROCK2 are activated (Drosophila melanogaster)


name: VAV exchanges GTP for GDP on RAC1, activating it (Drosophila melanogaster)


name: DOCK180:ELMO binds CRK (Drosophila melanogaster)


name: p-Y420-FYN is phosphorylated on S21 (Drosophila melanogaster)


name: p38 MAPK activation by VEGFR (Drosophila melanogaster)


name: p-VAV family:PIP3 binds RAC1:GDP (Drosophila melanogaster)


name: PAK2 binds NCK (Drosophila melanogaster)


name: VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K phosphorylates PIP2 to PIP3 (Drosophila melanogaster)


name: VEGFA-VEGFR2 Pathway (Caenorhabditis elegans)


name: Phosphorylation of SRC-1 (Caenorhabditis elegans)


name: ROCK1,ROCK2 are activated (Caenorhabditis elegans)


name: RHOA:GTP:Mg2+ binds ROCK1,ROCK2 (Caenorhabditis elegans)


name: p-MAPK2/3 phosphorylates HSP27 (Caenorhabditis elegans)


name: p-VAV family:PIP3 binds RAC1:GDP (Caenorhabditis elegans)


name: p-Y420-FYN is phosphorylated on S21 (Caenorhabditis elegans)


name: p38 MAPK activation by VEGFR (Caenorhabditis elegans)


name: FYN autophosphorylates (Caenorhabditis elegans)


name: VAV exchanges GTP for GDP on RAC1, activating it (Caenorhabditis elegans)


name: p-AXL binds PI3K (Caenorhabditis elegans)


name: PAK2 autophorylates (Caenorhabditis elegans)