name: STRA6 transports atROL from extracellular region to cytosol (Gallus gallus)


name: RBP3 regulates the transport of atROL from ROS to RPE (Gallus gallus)

category: biolink:MolecularActivity biolink:Occurrent biolink:OntologyClass biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent


name: TTR:RBP:atROL binds to STRA6 receptor (Gallus gallus)


name: Retinoid metabolism and transport (Gallus gallus)

category: biolink:Pathway biolink:OntologyClass biolink:BiologicalProcess biolink:Occurrent biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent


name: BCMO1:Fe2+ cleaves betaC to atRAL (Gallus gallus)


name: atREs binds to nascent CM (Gallus gallus)


name: RDH11 reduces RBP2:atRAL to RBP2:atROL (Gallus gallus)


name: Parenchymal atROL translocates to HSCs (Gallus gallus)


name: LRAT esterifies RBP2:atROL and FACYLs to atREs (Gallus gallus)


name: LRAT esterifies RBP1:atROL and FACYLs to atREs (Gallus gallus)


name: atROL binds RBP1 (parenchymal cell) (Gallus gallus)


name: BCO2:Fe2+ cleaves betaC to APO10al and bION (Gallus gallus)


name: Cytosolic CMs translocate to extracellular region (Gallus gallus)


name: AKRs reduce RBP2:atRAL to RBP2:atROL (Gallus gallus)


name: PLB1 hydrolyses RPALM to atROL (Gallus gallus)


name: The canonical retinoid cycle in rods (twilight vision) (Drosophila melanogaster)


name: RLBP1:11cRAL dissociates (Drosophila melanogaster)


name: RPE65 isomero-hydrolyses atREs to 11cROL (Drosophila melanogaster)


name: atROL binds RBP1 to form RBP1:atROL (Drosophila melanogaster)


name: RDH12 reduces atRAL to atROL (Drosophila melanogaster)


name: 11cROL binds to RLBP1 to form RLBP1:11cROL (Drosophila melanogaster)


name: RDH10,11 oxidise 11cROL to 11cRAL (Drosophila melanogaster)


name: Retinoid metabolism and transport (Drosophila melanogaster)


name: atROL binds RBP1 (parenchymal cell) (Drosophila melanogaster)


name: PLB1 hydrolyses RPALM to atROL (Drosophila melanogaster)


name: AKRs reduce RBP2:atRAL to RBP2:atROL (Drosophila melanogaster)


name: atRAL binds to RBP2 (Drosophila melanogaster)


name: atROL binds RBP1 (Drosophila melanogaster)


name: RDH11 reduces RBP2:atRAL to RBP2:atROL (Drosophila melanogaster)


name: Parenchymal atROL translocates to HSCs (Drosophila melanogaster)


name: atROL binds to RBP2 (Drosophila melanogaster)


name: BCO2:Fe2+ cleaves betaC to APO10al and bION (Drosophila melanogaster)


name: BCMO1:Fe2+ cleaves betaC to atRAL (Drosophila melanogaster)


name: The canonical retinoid cycle in rods (twilight vision) (Caenorhabditis elegans)


name: RPE65 isomero-hydrolyses atREs to 11cROL (Caenorhabditis elegans)


name: 11cRAL binds to opsin to form 11c-retinyl:RHO (Caenorhabditis elegans)


name: atROL binds RBP1 to form RBP1:atROL (Caenorhabditis elegans)


name: Retinoid metabolism and transport (Caenorhabditis elegans)


name: Parenchymal atROL translocates to HSCs (Caenorhabditis elegans)


name: BCO2:Fe2+ cleaves betaC to APO10al and bION (Caenorhabditis elegans)


name: atROL binds to RBP2 (Caenorhabditis elegans)


name: PLB1 hydrolyses RPALM to atROL (Caenorhabditis elegans)


name: RBP4 binds atROL (Caenorhabditis elegans)


name: atROL binds RBP1 (parenchymal cell) (Caenorhabditis elegans)


name: BCMO1:Fe2+ cleaves betaC to atRAL (Caenorhabditis elegans)


name: RBP4:atROL binds TTR (Caenorhabditis elegans)


name: AKRs reduce RBP2:atRAL to RBP2:atROL (Caenorhabditis elegans)


name: atROL binds RBP1 (Caenorhabditis elegans)


name: atRAL binds to RBP2 (Caenorhabditis elegans)


name: The canonical retinoid cycle in rods (twilight vision) (Dictyostelium discoideum)


name: 11cROL binds to RLBP1 to form RLBP1:11cROL (Dictyostelium discoideum)


name: RLBP1:11cRAL dissociates (Dictyostelium discoideum)


name: The canonical retinoid cycle in rods (twilight vision) (Plasmodium falciparum)


name: Retinoid cycle disease events (Homo sapiens)


name: Defective STRA6 does not transport atROL (Homo sapiens)


name: Defective OPN1MW causes COD5 (Homo sapiens)


name: Defective OPN1LW causes CBP (Homo sapiens)


name: Defective RDH12 does not reduce atRAL to atROL and causes LCA13 (Homo sapiens)


name: Defective OPN1MW causes DCB and BCM (Homo sapiens)


name: Defective OPN1SW causes tritanopia (Homo sapiens)


name: Defective ABCA4 does not transport NRPE from disc membranes (Homo sapiens)


name: Defective RDH5 does not oxidise 11cROL to 11cRAL and causes RPA (Homo sapiens)


name: Defective RDH12 does not reduce atRAL to atROL (Homo sapiens)


name: Defective OPN1LW causes BCM (Homo sapiens)


name: Defective LRAT does not esterify RBP1:atROL and FACYLs to atREs (Homo sapiens)


name: Aberrant regulation of mitotic exit in cancer due to RB1 defects (Homo sapiens)


name: Defective RB1 does not form a complex with SKP2 and FZR1 (Homo sapiens)


name: Defective translocation of RB1 mutants to the nucleus (Homo sapiens)


name: Defective RB1 does not translocate to the nucleus (Homo sapiens)


name: Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) (Homo sapiens)


name: Defective RB1 does not bind E2F1,(E2F2,E2F3) (Homo sapiens)


name: Defective Inhibition of DNA Recombination at Telomere Due to ATRX Mutations (Homo sapiens)


name: Defective ATRX does not bind DAXX (Homo sapiens)


name: Defective Inhibition of DNA Recombination at Telomere Due to DAXX Mutations (Homo sapiens)


name: Defective DAXX does not bind ATRX (Homo sapiens)


name: The GSDME gene promoter is hypermethylated (Homo sapiens)


name: Decitabine triphosphate incorporates into DNA (Homo sapiens)


name: GSDME variant does not bind PIPs (Homo sapiens)


name: Defective RIPK1-mediated regulated necrosis (Homo sapiens)


name: RIPK1 variant is not cleaved by CASP8 (Homo sapiens)


name: Microbial modulation of RIPK1-mediated regulated necrosis (Homo sapiens)


name: Loss of function of TP53 in cancer due to loss of tetramerization ability (Homo sapiens)


name: Defective TP53 does not tetramerize (Homo sapiens)


name: Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function (Homo sapiens)


name: p14ARF mutants do not bind C1QBP (Homo sapiens)


name: Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models (Homo sapiens)


name: CDK5:p25 phosphorylates lamin A (Homo sapiens)


name: CDK5:p25 phosphorylates JUN (Homo sapiens)


name: CDC25C binds YWHAE (14-3-3-epsilon) (Homo sapiens)


name: CDK5:p25 phosphorylates PRDX2 (Homo sapiens)


name: BCL2L11 (BIM) gene expression (Homo sapiens)


name: CDK5:p25 phosphorylates FOXO3 (Homo sapiens)


name: p25-bound CDK5 phosphorylates CDC25B (Homo sapiens)


name: CDK5:p25 phosphorylates lamin B1 (Homo sapiens)


name: CDK5:p25 phosphorylates PRDX1 (Homo sapiens)


name: FASLG (FasL) gene expression (Homo sapiens)


name: SOD2 (MnSOD) gene expression (Homo sapiens)


name: Influx of extracellular calcium (Homo sapiens)


name: CDK5:p25 translocates to the nucleus (Homo sapiens)


name: p25-bound CDK5 phosphorylates CDC25C (Homo sapiens)


name: Phosphorylated FOXO3 translocates to the nucleus (Homo sapiens)


name: CDK5:p25 phosphorylates GOLGA2 (Homo sapiens)


name: Calpain cleaves p35 to p25 (Homo sapiens)


name: p25-bound CDK5 phosphorylates CDC25A (Homo sapiens)


name: CAST binds Ca2+ bound calpain (Homo sapiens)


name: Impaired BRCA2 binding to RAD51 (Homo sapiens)


name: BRCA2 mutants with BRC defects or a defect in the C-terminal RAD51 binding site do not bind RAD51 (Homo sapiens)


name: Impaired BRCA2 binding to PALB2 (Homo sapiens)


name: Defective recruitment of BRCA2 and RAD51 due to loss of BRCA2 function in PALB2 binding (Homo sapiens)


name: Impaired BRCA2 binding to SEM1 (DSS1) (Homo sapiens)


name: BRCA2 mutants do not bind SEM1 (DSS1) (Homo sapiens)


name: Impaired BRCA2 translocation to the nucleus (Homo sapiens)


name: Defective BRCA2 does not translocate to the nucleus (Homo sapiens)


name: Defective DNA double strand break response due to BRCA1 loss of function (Homo sapiens)


name: Some pathogenic BRCA1 mutants do not bind BARD1 (Homo sapiens)


name: Defective homologous recombination repair (HRR) due to BRCA1 loss of function (Homo sapiens)


name: Defective D-loop formation mediated by PALB2, BRCA2 and RAD51 due to loss-of-function of BRCA1 in PALB2 binding (Homo sapiens)


name: Defective DNA double strand break response due to BARD1 loss of function (Homo sapiens)


name: Defective BARD1 does not bind BRCA1 (Homo sapiens)


name: Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function (Homo sapiens)


name: Defective D-loop formation mediated by PALB2, BRCA2 and RAD51 due to loss-of-function of PALB2 in binding to BRCA2/RAD51/RAD51C (Homo sapiens)


name: Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function (Homo sapiens)


name: Defective D-loop formation mediated by PALB2, BRCA2 and RAD51 due to loss-of-function of PALB2 in BRCA1 binding (Homo sapiens)


name: Defective Mismatch Repair Associated With MSH2 (Homo sapiens)


name: MSH2 variant:MSH3-defective DNA mismatch repair (Homo sapiens)


name: MSH2 variant:MSH6-defective DNA mismatch repair (Homo sapiens)


name: Defective Mismatch Repair Associated With MSH3 (Homo sapiens)


name: MSH3 variant:MSH2-defective DNA mismatch repair (Homo sapiens)


name: Defective Mismatch Repair Associated With MSH6 (Homo sapiens)


name: MSH6 variant:MSH2-defective DNA mismatch repair (Homo sapiens)


name: Defective Mismatch Repair Associated With PMS2 (Homo sapiens)


name: PMS2 variants-defective DNA mismatch repair (Homo sapiens)


name: Defective Mismatch Repair Associated With MLH1 (Homo sapiens)


name: MLH1 variants-defective DNA mismatch repair (Homo sapiens)


name: Defective Base Excision Repair Associated with NEIL3 (Homo sapiens)


name: NEIL3 D132V does not cleave 5-guanidinohydantoin (Gh) (Homo sapiens)


name: NEIL3-mediated resolution of ICLs (Homo sapiens)


name: NEIL3 resolves psoralen-induced ICLs (Homo sapiens)


name: NEIL3 resolves abasic site-induced ICLs (Homo sapiens)


name: Alkylating DNA damage induced by chemotherapeutic drugs (Homo sapiens)


name: Monofunctional chemotherapeutic alkylating drugs produce 7-methylguanine in dsDNA (Homo sapiens)


name: Monofunctional chemotherapeutic alkylating drugs produce 3-methyladenine in dsDNA (Homo sapiens)


name: Cleavage of the damaged purine (Homo sapiens)


name: NEIL3 cleaves 5-guanidinohydantoin (Homo sapiens)


name: Cleavage of ethenoadenine by MPG glycosylase (Homo sapiens)


name: Cleavage of hypoxanthine by MPG glycosylase (Homo sapiens)


name: NEIL3 cleaves spiroiminodihydantoin from damaged telomeric DNA (Homo sapiens)


name: Cleavage of 3-methyladenine by MPG glycosylase  (Homo sapiens)


name: Cleavage of adenine mispaired with 8-oxoguanine by MUTYH (Homo sapiens)


name: NEIL3 cleaves spiroiminodihydantoin (Homo sapiens)


name: NEIL3 cleaves 5-guanidinohydantoin (Gh) from damaged telomeric DNA (Homo sapiens)


name: Excision of 8-oxoguanine by OGG1 glycosylase (Homo sapiens)


name: Recognition and association of DNA glycosylase with site containing an affected purine (Homo sapiens)


name: NEIL3 recognizes and binds to spiroiminodihydantoin in telomeric DNA (Homo sapiens)


name: MPG glycosylase mediated recognition and binding of 3-methyladenine  (Homo sapiens)


name: MPG glycosylase mediated recognition and binding of ethenoadenine  (Homo sapiens)


name: NEIL3 recognizes and binds to 5-guanidinohydantoin (Homo sapiens)


name: MUTYH mediated recognition and binding of an adenine opposite to an 8-oxoguanine (Homo sapiens)


name: OGG1 glycosylase mediated recognition and binding of an 8-oxoguanine opposite to a cytosine (Homo sapiens)


name: NEIL3 recognizes and binds to 5-guanidinohydantoin (Gh) in telomeric DNA (Homo sapiens)


name: NEIL3 recognizes and binds to spiroiminodihydantoin (Homo sapiens)


name: MPG glycosylase mediated recognition and binding of hypoxanthine (Homo sapiens)


name: OGG1beta translocates to mitochondria (Homo sapiens)


name: Recognition and association of DNA glycosylase with site containing an affected purine (Mus musculus)


name: NEIL3 recognizes and binds to 5-guanidinohydantoin (Gh) in telomeric DNA (Mus musculus)


name: OGG1beta translocates to mitochondria (Mus musculus)


name: Recognition and association of DNA glycosylase with site containing an affected purine (Rattus norvegicus)


name: NEIL3 recognizes and binds to 5-guanidinohydantoin (Gh) in telomeric DNA (Rattus norvegicus)


name: OGG1beta translocates to mitochondria (Rattus norvegicus)


name: Recognition and association of DNA glycosylase with site containing an affected purine (Canis familiaris)


name: NEIL3 recognizes and binds to 5-guanidinohydantoin (Gh) in telomeric DNA (Canis familiaris)


name: OGG1beta translocates to mitochondria (Canis familiaris)


name: Recognition and association of DNA glycosylase with site containing an affected purine (Bos taurus)


name: NEIL3 recognizes and binds to 5-guanidinohydantoin (Gh) in telomeric DNA (Bos taurus)


name: OGG1beta translocates to mitochondria (Bos taurus)


name: Recognition and association of DNA glycosylase with site containing an affected purine (Sus scrofa)


name: NEIL3 recognizes and binds to 5-guanidinohydantoin (Gh) in telomeric DNA (Sus scrofa)


name: Recognition and association of DNA glycosylase with site containing an affected purine (Xenopus tropicalis)


name: NEIL3 recognizes and binds to 5-guanidinohydantoin (Gh) in telomeric DNA (Xenopus tropicalis)


name: Recognition and association of DNA glycosylase with site containing an affected purine (Drosophila melanogaster)


name: OGG1beta translocates to mitochondria (Drosophila melanogaster)


name: Recognition and association of DNA glycosylase with site containing an affected purine (Dictyostelium discoideum)


name: OGG1beta translocates to mitochondria (Dictyostelium discoideum)


name: Recognition and association of DNA glycosylase with site containing an affected purine (Saccharomyces cerevisiae)


name: OGG1beta translocates to mitochondria (Saccharomyces cerevisiae)


name: Recognition and association of DNA glycosylase with site containing an affected purine (Plasmodium falciparum)


name: OGG1beta translocates to mitochondria (Plasmodium falciparum)


name: Cleavage of the damaged purine (Mus musculus)


name: NEIL3 cleaves 5-guanidinohydantoin (Mus musculus)


name: Cleavage of ethenoadenine by MPG glycosylase (Mus musculus)


name: Cleavage of adenine mispaired with 8-oxoguanine by MUTYH (Mus musculus)


name: NEIL3 cleaves spiroiminodihydantoin (Mus musculus)


name: NEIL3 cleaves 5-guanidinohydantoin (Gh) from damaged telomeric DNA (Mus musculus)


name: Cleavage of hypoxanthine by MPG glycosylase (Mus musculus)


name: Cleavage of 3-methyladenine by MPG glycosylase  (Mus musculus)


name: Excision of 8-oxoguanine by OGG1 glycosylase (Mus musculus)


name: Cleavage of the damaged purine (Rattus norvegicus)


name: NEIL3 cleaves 5-guanidinohydantoin (Rattus norvegicus)


name: Cleavage of 3-methyladenine by MPG glycosylase  (Rattus norvegicus)


name: Cleavage of hypoxanthine by MPG glycosylase (Rattus norvegicus)


name: Cleavage of ethenoadenine by MPG glycosylase (Rattus norvegicus)


name: Cleavage of adenine mispaired with 8-oxoguanine by MUTYH (Rattus norvegicus)


name: NEIL3 cleaves spiroiminodihydantoin (Rattus norvegicus)


name: NEIL3 cleaves 5-guanidinohydantoin (Gh) from damaged telomeric DNA (Rattus norvegicus)


name: Excision of 8-oxoguanine by OGG1 glycosylase (Rattus norvegicus)


name: Cleavage of the damaged purine (Canis familiaris)


name: NEIL3 cleaves 5-guanidinohydantoin (Canis familiaris)


name: Cleavage of ethenoadenine by MPG glycosylase (Canis familiaris)


name: Cleavage of adenine mispaired with 8-oxoguanine by MUTYH (Canis familiaris)


name: NEIL3 cleaves spiroiminodihydantoin (Canis familiaris)


name: NEIL3 cleaves 5-guanidinohydantoin (Gh) from damaged telomeric DNA (Canis familiaris)


name: Excision of 8-oxoguanine by OGG1 glycosylase (Canis familiaris)


name: Cleavage of hypoxanthine by MPG glycosylase (Canis familiaris)


name: Cleavage of 3-methyladenine by MPG glycosylase  (Canis familiaris)


name: Cleavage of the damaged purine (Bos taurus)


name: Cleavage of hypoxanthine by MPG glycosylase (Bos taurus)


name: NEIL3 cleaves 5-guanidinohydantoin (Bos taurus)


name: Excision of 8-oxoguanine by OGG1 glycosylase (Bos taurus)


name: Cleavage of 3-methyladenine by MPG glycosylase  (Bos taurus)


name: Cleavage of ethenoadenine by MPG glycosylase (Bos taurus)


name: Cleavage of adenine mispaired with 8-oxoguanine by MUTYH (Bos taurus)


name: NEIL3 cleaves spiroiminodihydantoin (Bos taurus)


name: NEIL3 cleaves 5-guanidinohydantoin (Gh) from damaged telomeric DNA (Bos taurus)


name: Cleavage of the damaged purine (Sus scrofa)


name: Cleavage of hypoxanthine by MPG glycosylase (Sus scrofa)


name: Cleavage of 3-methyladenine by MPG glycosylase  (Sus scrofa)


name: NEIL3 cleaves spiroiminodihydantoin (Sus scrofa)


name: NEIL3 cleaves 5-guanidinohydantoin (Gh) from damaged telomeric DNA (Sus scrofa)


name: Cleavage of ethenoadenine by MPG glycosylase (Sus scrofa)


name: Cleavage of adenine mispaired with 8-oxoguanine by MUTYH (Sus scrofa)


name: NEIL3 cleaves 5-guanidinohydantoin (Sus scrofa)


name: Cleavage of the damaged purine (Danio rerio)


name: Cleavage of hypoxanthine by MPG glycosylase (Danio rerio)


name: Cleavage of 3-methyladenine by MPG glycosylase  (Danio rerio)


name: Cleavage of ethenoadenine by MPG glycosylase (Danio rerio)


name: Cleavage of the damaged purine (Xenopus tropicalis)


name: NEIL3 cleaves 5-guanidinohydantoin (Xenopus tropicalis)


name: Cleavage of 3-methyladenine by MPG glycosylase  (Xenopus tropicalis)


name: Cleavage of hypoxanthine by MPG glycosylase (Xenopus tropicalis)


name: NEIL3 cleaves spiroiminodihydantoin (Xenopus tropicalis)


name: NEIL3 cleaves 5-guanidinohydantoin (Gh) from damaged telomeric DNA (Xenopus tropicalis)


name: Cleavage of ethenoadenine by MPG glycosylase (Xenopus tropicalis)


name: Cleavage of adenine mispaired with 8-oxoguanine by MUTYH (Xenopus tropicalis)


name: Cleavage of the damaged purine (Gallus gallus)


name: Cleavage of ethenoadenine by MPG glycosylase (Gallus gallus)


name: Cleavage of adenine mispaired with 8-oxoguanine by MUTYH (Gallus gallus)


name: NEIL3 cleaves spiroiminodihydantoin (Gallus gallus)


name: NEIL3 cleaves 5-guanidinohydantoin (Gallus gallus)


name: Cleavage of hypoxanthine by MPG glycosylase (Gallus gallus)


name: Cleavage of 3-methyladenine by MPG glycosylase  (Gallus gallus)


name: Cleavage of the damaged purine (Drosophila melanogaster)


name: Excision of 8-oxoguanine by OGG1 glycosylase (Drosophila melanogaster)


name: Cleavage of the damaged purine (Dictyostelium discoideum)


name: Cleavage of adenine mispaired with 8-oxoguanine by MUTYH (Dictyostelium discoideum)


name: Excision of 8-oxoguanine by OGG1 glycosylase (Dictyostelium discoideum)


name: Cleavage of the damaged purine (Schizosaccharomyces pombe)


name: Cleavage of adenine mispaired with 8-oxoguanine by MUTYH (Schizosaccharomyces pombe)


name: Cleavage of the damaged purine (Saccharomyces cerevisiae)


name: Excision of 8-oxoguanine by OGG1 glycosylase (Saccharomyces cerevisiae)


name: Cleavage of the damaged purine (Plasmodium falciparum)


name: Cleavage of hypoxanthine by MPG glycosylase (Plasmodium falciparum)


name: Excision of 8-oxoguanine by OGG1 glycosylase (Plasmodium falciparum)


name: Cleavage of 3-methyladenine by MPG glycosylase  (Plasmodium falciparum)


name: Cleavage of ethenoadenine by MPG glycosylase (Plasmodium falciparum)


name: Cleavage of adenine mispaired with 8-oxoguanine by MUTYH (Plasmodium falciparum)


name: Cleavage of the damaged pyrimidine  (Homo sapiens)


name: NEIL1 cleaves FapyA from damaged DNA (Homo sapiens)


name: Cleavage of ethenocytosine by TDG glycosylase  (Homo sapiens)


name: Cleavage of thymine by MBD4 glycosylase (Homo sapiens)


name: NEIL1 cleaves FapyG from damaged DNA (Homo sapiens)


name: Cleavage of uracil by MBD4 glycosylase (Homo sapiens)


name: Cleavage of formamidopyrimidine (FapyA) by NTHL1 glycosylase  (Homo sapiens)


name: Cleavage of cytosine glycol by NTHL1 glycosylase (Homo sapiens)


name: Cleavage of dihydrouracil by NTHL1 glycosylase (Homo sapiens)


name: Cleavage of thymine glycol by NTHL1 glycosylase   (Homo sapiens)


name: NEIL1 cleaves thymine glycol from damaged DNA (Homo sapiens)


name: NEIL1 cleaves DHU from damaged DNA (Homo sapiens)


name: single-strand selective uracil DNA N-glycosylase activity

description: Catalysis of the cleavage of the N-C1' glycosidic bond between the damaged DNA base and the deoxyribose sugar, releasing a free base and leaving an apyrimidinic (AP) site. Enzymes with this activity recognize and remove uracil bases present in single-stranded DNA.


name: NEIL3 cleaves thymine glycol from telomeric DNA (Homo sapiens)


name: Cleavage of uracil by TDG glycosylase (Homo sapiens)


name: Cleavage of thymine by TDG glycosylase (Homo sapiens)


name: NEIL3 cleaves thymine glycol (Homo sapiens)


name: Cleavage of 5-hydroxyluracil by UNG glycosylase (Homo sapiens)


name: NEIL2 cleaves 5-OHU from damaged DNA (Homo sapiens)


name: Cleavage of uracil by UNG glycosylase (Homo sapiens)


name: Excision of FapyG by OGG1 glycosylase (Homo sapiens)


name: Recognition and association of DNA glycosylase with site containing an affected pyrimidine (Homo sapiens)


name: OGG1 glycosylase mediated recognition and binding of a formamidopyrimidine (FapyG) (Homo sapiens)


name: MBD4 glycosylase mediated recognition and binding of a thymine opposite to a guanine at CpG sequences (Homo sapiens)


name: MBD4 glycosylase mediated recognition and binding of an uracil opposite to a guanine at CpG sequences (Homo sapiens)


name: SMUG1 glycosylase mediated recognition and binding of uracil in DNA (Homo sapiens)


name: NEIL1 recognizes and binds FapyA-dsDNA (Homo sapiens)


name: NEIL1 recognizes and binds thymine glycol (Homo sapiens)


name: NEIL1 recognizes and binds FapyG-dsDNA (Homo sapiens)


name: TDG glycosylase mediated recognition and binding of a thymine opposite to a guanine (Homo sapiens)


name: NEIL3 recognizes and binds to thymine glycol in telomeric DNA (Homo sapiens)


name: TDG glycosylase mediated recognition and binding of an uracil opposite to a guanine (Homo sapiens)


name: UNG glycosylase mediated recognition and binding of an uracil opposite to a guanine (Homo sapiens)


name: NEIL1 translocates to the nucleus (Homo sapiens)


name: UNG glycosylase mediated recognition and binding of a 5-hydroxyuracil opposite to a guanine (Homo sapiens)


name: NEIL3 recognizes and binds to thymine glycol (Homo sapiens)


name: NTHL1 glycosylase mediated recognition and binding of dihydrouracil (Homo sapiens)


name: NTHL1 glycosylase mediated recognition and binding of formamidopyrimidine (FapyA) (Homo sapiens)


name: TDG glycosylase mediated recognition and binding of an ethenocytosine (Homo sapiens)


name: NTHL1 glycosylase mediated recognition and binding of thymine glycol (Homo sapiens)


name: NEIL1 recognizes and binds DHU-dsDNA (Homo sapiens)


name: NTHL1 glycosylase mediated recognition and binding of cytosine glycol (Homo sapiens)


name: NEIL2 recognizes and binds 5-OHU-dsDNA (Homo sapiens)


name: Recognition and association of DNA glycosylase with site containing an affected pyrimidine (Mus musculus)


name: NEIL1 translocates to the nucleus (Mus musculus)


name: Recognition and association of DNA glycosylase with site containing an affected pyrimidine (Rattus norvegicus)


name: NEIL1 translocates to the nucleus (Rattus norvegicus)


name: Recognition and association of DNA glycosylase with site containing an affected pyrimidine (Canis familiaris)


name: NEIL1 translocates to the nucleus (Canis familiaris)


name: Recognition and association of DNA glycosylase with site containing an affected pyrimidine (Bos taurus)


name: NEIL1 translocates to the nucleus (Bos taurus)


name: Recognition and association of DNA glycosylase with site containing an affected pyrimidine (Sus scrofa)


name: NEIL1 translocates to the nucleus (Sus scrofa)


name: Recognition and association of DNA glycosylase with site containing an affected pyrimidine (Danio rerio)


name: NEIL1 translocates to the nucleus (Danio rerio)


name: Recognition and association of DNA glycosylase with site containing an affected pyrimidine (Xenopus tropicalis)


name: NEIL1 translocates to the nucleus (Xenopus tropicalis)


name: Recognition and association of DNA glycosylase with site containing an affected pyrimidine (Gallus gallus)


name: NEIL1 translocates to the nucleus (Gallus gallus)


name: Cleavage of the damaged pyrimidine  (Mus musculus)


name: NEIL1 cleaves thymine glycol from damaged DNA (Mus musculus)


name: Cleavage of formamidopyrimidine (FapyA) by NTHL1 glycosylase  (Mus musculus)


name: NEIL1 cleaves FapyG from damaged DNA (Mus musculus)


name: Cleavage of uracil by SMUG1 glycosylase (Mus musculus)


name: Cleavage of uracil by UNG glycosylase (Mus musculus)


name: Cleavage of thymine by TDG glycosylase (Mus musculus)


name: Cleavage of dihydrouracil by NTHL1 glycosylase (Mus musculus)


name: NEIL1 cleaves FapyA from damaged DNA (Mus musculus)


name: Cleavage of ethenocytosine by TDG glycosylase  (Mus musculus)


name: Cleavage of uracil by MBD4 glycosylase (Mus musculus)


name: NEIL2 cleaves 5-OHU from damaged DNA (Mus musculus)


name: Cleavage of uracil by TDG glycosylase (Mus musculus)


name: Excision of FapyG by OGG1 glycosylase (Mus musculus)


name: Cleavage of cytosine glycol by NTHL1 glycosylase (Mus musculus)


name: Cleavage of thymine by MBD4 glycosylase (Mus musculus)


name: NEIL1 cleaves DHU from damaged DNA (Mus musculus)


name: Cleavage of 5-hydroxyluracil by UNG glycosylase (Mus musculus)


name: Cleavage of thymine glycol by NTHL1 glycosylase   (Mus musculus)


name: Cleavage of the damaged pyrimidine  (Rattus norvegicus)


name: Cleavage of uracil by MBD4 glycosylase (Rattus norvegicus)


name: Cleavage of thymine glycol by NTHL1 glycosylase   (Rattus norvegicus)


name: Cleavage of 5-hydroxyluracil by UNG glycosylase (Rattus norvegicus)


name: NEIL1 cleaves FapyA from damaged DNA (Rattus norvegicus)


name: Excision of FapyG by OGG1 glycosylase (Rattus norvegicus)


name: Cleavage of thymine by MBD4 glycosylase (Rattus norvegicus)


name: Cleavage of cytosine glycol by NTHL1 glycosylase (Rattus norvegicus)


name: NEIL2 cleaves 5-OHU from damaged DNA (Rattus norvegicus)


name: Cleavage of uracil by TDG glycosylase (Rattus norvegicus)


name: NEIL1 cleaves DHU from damaged DNA (Rattus norvegicus)


name: Cleavage of ethenocytosine by TDG glycosylase  (Rattus norvegicus)


name: Cleavage of dihydrouracil by NTHL1 glycosylase (Rattus norvegicus)


name: Cleavage of thymine by TDG glycosylase (Rattus norvegicus)


name: NEIL1 cleaves thymine glycol from damaged DNA (Rattus norvegicus)


name: NEIL1 cleaves FapyG from damaged DNA (Rattus norvegicus)


name: Cleavage of uracil by SMUG1 glycosylase (Rattus norvegicus)


name: Cleavage of uracil by UNG glycosylase (Rattus norvegicus)


name: Cleavage of formamidopyrimidine (FapyA) by NTHL1 glycosylase  (Rattus norvegicus)


name: Cleavage of the damaged pyrimidine  (Canis familiaris)


name: Cleavage of uracil by SMUG1 glycosylase (Canis familiaris)


name: Cleavage of uracil by UNG glycosylase (Canis familiaris)


name: NEIL2 cleaves 5-OHU from damaged DNA (Canis familiaris)


name: Cleavage of formamidopyrimidine (FapyA) by NTHL1 glycosylase  (Canis familiaris)


name: Cleavage of thymine glycol by NTHL1 glycosylase   (Canis familiaris)


name: Cleavage of uracil by MBD4 glycosylase (Canis familiaris)


name: NEIL1 cleaves DHU from damaged DNA (Canis familiaris)


name: Cleavage of 5-hydroxyluracil by UNG glycosylase (Canis familiaris)


name: NEIL1 cleaves FapyG from damaged DNA (Canis familiaris)


name: Cleavage of cytosine glycol by NTHL1 glycosylase (Canis familiaris)


name: NEIL1 cleaves thymine glycol from damaged DNA (Canis familiaris)


name: Cleavage of thymine by MBD4 glycosylase (Canis familiaris)


name: Excision of FapyG by OGG1 glycosylase (Canis familiaris)


name: Cleavage of uracil by TDG glycosylase (Canis familiaris)


name: Cleavage of ethenocytosine by TDG glycosylase  (Canis familiaris)


name: Cleavage of thymine by TDG glycosylase (Canis familiaris)


name: Cleavage of dihydrouracil by NTHL1 glycosylase (Canis familiaris)


name: NEIL1 cleaves FapyA from damaged DNA (Canis familiaris)


name: Cleavage of the damaged pyrimidine  (Bos taurus)


name: Cleavage of thymine by TDG glycosylase (Bos taurus)


name: Cleavage of ethenocytosine by TDG glycosylase  (Bos taurus)


name: NEIL1 cleaves thymine glycol from damaged DNA (Bos taurus)


name: NEIL1 cleaves FapyG from damaged DNA (Bos taurus)


name: Cleavage of dihydrouracil by NTHL1 glycosylase (Bos taurus)


name: Cleavage of formamidopyrimidine (FapyA) by NTHL1 glycosylase  (Bos taurus)


name: NEIL1 cleaves FapyA from damaged DNA (Bos taurus)


name: Cleavage of uracil by SMUG1 glycosylase (Bos taurus)


name: Cleavage of thymine glycol by NTHL1 glycosylase   (Bos taurus)


name: Cleavage of uracil by TDG glycosylase (Bos taurus)


name: NEIL2 cleaves 5-OHU from damaged DNA (Bos taurus)


name: Cleavage of uracil by MBD4 glycosylase (Bos taurus)


name: Cleavage of thymine by MBD4 glycosylase (Bos taurus)


name: NEIL1 cleaves DHU from damaged DNA (Bos taurus)


name: Cleavage of cytosine glycol by NTHL1 glycosylase (Bos taurus)


name: Excision of FapyG by OGG1 glycosylase (Bos taurus)


name: Cleavage of the damaged pyrimidine  (Sus scrofa)


name: NEIL1 cleaves DHU from damaged DNA (Sus scrofa)


name: Cleavage of thymine by TDG glycosylase (Sus scrofa)


name: NEIL1 cleaves FapyG from damaged DNA (Sus scrofa)


name: Cleavage of dihydrouracil by NTHL1 glycosylase (Sus scrofa)


name: Cleavage of ethenocytosine by TDG glycosylase  (Sus scrofa)


name: Cleavage of formamidopyrimidine (FapyA) by NTHL1 glycosylase  (Sus scrofa)


name: NEIL1 cleaves FapyA from damaged DNA (Sus scrofa)


name: Cleavage of uracil by SMUG1 glycosylase (Sus scrofa)


name: Cleavage of uracil by UNG glycosylase (Sus scrofa)


name: Cleavage of 5-hydroxyluracil by UNG glycosylase (Sus scrofa)


name: NEIL2 cleaves 5-OHU from damaged DNA (Sus scrofa)


name: Cleavage of thymine glycol by NTHL1 glycosylase   (Sus scrofa)


name: Cleavage of uracil by MBD4 glycosylase (Sus scrofa)


name: Cleavage of uracil by TDG glycosylase (Sus scrofa)


name: NEIL1 cleaves thymine glycol from damaged DNA (Sus scrofa)


name: Cleavage of cytosine glycol by NTHL1 glycosylase (Sus scrofa)


name: Cleavage of thymine by MBD4 glycosylase (Sus scrofa)


name: Cleavage of the damaged pyrimidine  (Danio rerio)


name: NEIL1 cleaves DHU from damaged DNA (Danio rerio)


name: NEIL1 cleaves FapyA from damaged DNA (Danio rerio)


name: Cleavage of thymine by TDG glycosylase (Danio rerio)


name: Cleavage of 5-hydroxyluracil by UNG glycosylase (Danio rerio)


name: NEIL1 cleaves thymine glycol from damaged DNA (Danio rerio)


name: NEIL1 cleaves FapyG from damaged DNA (Danio rerio)


name: Cleavage of ethenocytosine by TDG glycosylase  (Danio rerio)


name: Cleavage of uracil by TDG glycosylase (Danio rerio)


name: Cleavage of uracil by UNG glycosylase (Danio rerio)


name: Cleavage of the damaged pyrimidine  (Xenopus tropicalis)


name: Cleavage of thymine glycol by NTHL1 glycosylase   (Xenopus tropicalis)


name: NEIL1 cleaves thymine glycol from damaged DNA (Xenopus tropicalis)


name: Cleavage of 5-hydroxyluracil by UNG glycosylase (Xenopus tropicalis)


name: NEIL2 cleaves 5-OHU from damaged DNA (Xenopus tropicalis)


name: Cleavage of uracil by SMUG1 glycosylase (Xenopus tropicalis)


name: Cleavage of uracil by UNG glycosylase (Xenopus tropicalis)


name: Cleavage of formamidopyrimidine (FapyA) by NTHL1 glycosylase  (Xenopus tropicalis)


name: Cleavage of ethenocytosine by TDG glycosylase  (Xenopus tropicalis)


name: NEIL1 cleaves FapyA from damaged DNA (Xenopus tropicalis)


name: Cleavage of dihydrouracil by NTHL1 glycosylase (Xenopus tropicalis)


name: Cleavage of thymine by TDG glycosylase (Xenopus tropicalis)


name: NEIL1 cleaves FapyG from damaged DNA (Xenopus tropicalis)


name: Cleavage of thymine by MBD4 glycosylase (Xenopus tropicalis)


name: Cleavage of cytosine glycol by NTHL1 glycosylase (Xenopus tropicalis)


name: Cleavage of uracil by TDG glycosylase (Xenopus tropicalis)


name: NEIL1 cleaves DHU from damaged DNA (Xenopus tropicalis)


name: Cleavage of uracil by MBD4 glycosylase (Xenopus tropicalis)


name: Cleavage of the damaged pyrimidine  (Gallus gallus)


name: Cleavage of formamidopyrimidine (FapyA) by NTHL1 glycosylase  (Gallus gallus)


name: Cleavage of uracil by SMUG1 glycosylase (Gallus gallus)


name: Cleavage of uracil by UNG glycosylase (Gallus gallus)


name: Cleavage of ethenocytosine by TDG glycosylase  (Gallus gallus)


name: NEIL2 cleaves 5-OHU from damaged DNA (Gallus gallus)


name: Cleavage of thymine by TDG glycosylase (Gallus gallus)


name: Cleavage of dihydrouracil by NTHL1 glycosylase (Gallus gallus)


name: Cleavage of thymine by MBD4 glycosylase (Gallus gallus)


name: Cleavage of uracil by TDG glycosylase (Gallus gallus)


name: NEIL1 cleaves FapyA from damaged DNA (Gallus gallus)


name: Cleavage of cytosine glycol by NTHL1 glycosylase (Gallus gallus)


name: NEIL1 cleaves FapyG from damaged DNA (Gallus gallus)


name: Cleavage of thymine glycol by NTHL1 glycosylase   (Gallus gallus)


name: NEIL1 cleaves thymine glycol from damaged DNA (Gallus gallus)


name: Cleavage of uracil by MBD4 glycosylase (Gallus gallus)


name: Cleavage of 5-hydroxyluracil by UNG glycosylase (Gallus gallus)


name: NEIL1 cleaves DHU from damaged DNA (Gallus gallus)


name: Cleavage of the damaged pyrimidine  (Drosophila melanogaster)


name: Excision of FapyG by OGG1 glycosylase (Drosophila melanogaster)


name: Cleavage of thymine glycol by NTHL1 glycosylase   (Drosophila melanogaster)


name: Cleavage of ethenocytosine by TDG glycosylase  (Drosophila melanogaster)


name: Cleavage of thymine by TDG glycosylase (Drosophila melanogaster)


name: Cleavage of dihydrouracil by NTHL1 glycosylase (Drosophila melanogaster)


name: Cleavage of cytosine glycol by NTHL1 glycosylase (Drosophila melanogaster)


name: Cleavage of uracil by SMUG1 glycosylase (Drosophila melanogaster)


name: Cleavage of formamidopyrimidine (FapyA) by NTHL1 glycosylase  (Drosophila melanogaster)


name: Cleavage of uracil by TDG glycosylase (Drosophila melanogaster)


name: Cleavage of the damaged pyrimidine  (Caenorhabditis elegans)


name: Cleavage of dihydrouracil by NTHL1 glycosylase (Caenorhabditis elegans)


name: Cleavage of thymine glycol by NTHL1 glycosylase   (Caenorhabditis elegans)


name: Cleavage of cytosine glycol by NTHL1 glycosylase (Caenorhabditis elegans)


name: Cleavage of formamidopyrimidine (FapyA) by NTHL1 glycosylase  (Caenorhabditis elegans)


name: Cleavage of the damaged pyrimidine  (Dictyostelium discoideum)


name: Cleavage of cytosine glycol by NTHL1 glycosylase (Dictyostelium discoideum)


name: Cleavage of 5-hydroxyluracil by UNG glycosylase (Dictyostelium discoideum)


name: Excision of FapyG by OGG1 glycosylase (Dictyostelium discoideum)


name: Cleavage of formamidopyrimidine (FapyA) by NTHL1 glycosylase  (Dictyostelium discoideum)


name: Cleavage of thymine glycol by NTHL1 glycosylase   (Dictyostelium discoideum)


name: Cleavage of uracil by UNG glycosylase (Dictyostelium discoideum)


name: Cleavage of dihydrouracil by NTHL1 glycosylase (Dictyostelium discoideum)


name: Cleavage of the damaged pyrimidine  (Schizosaccharomyces pombe)


name: Cleavage of formamidopyrimidine (FapyA) by NTHL1 glycosylase  (Schizosaccharomyces pombe)


name: Cleavage of cytosine glycol by NTHL1 glycosylase (Schizosaccharomyces pombe)


name: Cleavage of thymine by TDG glycosylase (Schizosaccharomyces pombe)


name: Cleavage of 5-hydroxyluracil by UNG glycosylase (Schizosaccharomyces pombe)


name: Cleavage of ethenocytosine by TDG glycosylase  (Schizosaccharomyces pombe)


name: Cleavage of dihydrouracil by NTHL1 glycosylase (Schizosaccharomyces pombe)


name: Cleavage of thymine glycol by NTHL1 glycosylase   (Schizosaccharomyces pombe)


name: Cleavage of uracil by TDG glycosylase (Schizosaccharomyces pombe)


name: Cleavage of uracil by UNG glycosylase (Schizosaccharomyces pombe)


name: Cleavage of the damaged pyrimidine  (Saccharomyces cerevisiae)


name: Cleavage of dihydrouracil by NTHL1 glycosylase (Saccharomyces cerevisiae)


name: Cleavage of thymine glycol by NTHL1 glycosylase   (Saccharomyces cerevisiae)


name: Cleavage of uracil by UNG glycosylase (Saccharomyces cerevisiae)


name: Cleavage of formamidopyrimidine (FapyA) by NTHL1 glycosylase  (Saccharomyces cerevisiae)


name: Cleavage of cytosine glycol by NTHL1 glycosylase (Saccharomyces cerevisiae)


name: Cleavage of 5-hydroxyluracil by UNG glycosylase (Saccharomyces cerevisiae)


name: Excision of FapyG by OGG1 glycosylase (Saccharomyces cerevisiae)


name: Cleavage of the damaged pyrimidine  (Plasmodium falciparum)


name: Cleavage of cytosine glycol by NTHL1 glycosylase (Plasmodium falciparum)


name: Cleavage of 5-hydroxyluracil by UNG glycosylase (Plasmodium falciparum)


name: Excision of FapyG by OGG1 glycosylase (Plasmodium falciparum)


name: Cleavage of dihydrouracil by NTHL1 glycosylase (Plasmodium falciparum)


name: Cleavage of thymine glycol by NTHL1 glycosylase   (Plasmodium falciparum)


name: Cleavage of uracil by UNG glycosylase (Plasmodium falciparum)


name: Cleavage of formamidopyrimidine (FapyA) by NTHL1 glycosylase  (Plasmodium falciparum)


name: Resolution of Abasic Sites (AP sites) (Homo sapiens)


name: APEX1 mediates endonucleolytic cleavage at the 5' side of the AP site (Homo sapiens)


name: APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway (Homo sapiens)


name: PNKP hydrolyzes the terminal 3'Pi at the NEIL1,NEIL2-generated single strand break (SSB) (Homo sapiens)


name: POLB incorporates a single nucleotide in place of excised AP residue in NEIL1,NEIL2-mediated AP site resolution (Homo sapiens)


name: POLB excises the NEIL1,NEIL2-bound AP site (5'dRP) (Homo sapiens)


name: LIG3:XRCC1, POLB, NEIL1,NEIL2 and PNKP dissociate from the BER site (Homo sapiens)


name: NEIL1,NEIL2 recruits POLB to incised AP site (Homo sapiens)


name: NEIL1,NEIL2 incises DNA strand 5' to the AP site (Homo sapiens)


name: LIG3:XRCC1 and PNKP bind NEIL1,NEIL2:POLB:SSB(3'Pi)-gap-dsDNA (Homo sapiens)


name: NEIL1,NEIL2 displace OGG1 from AP-dsDNA (Homo sapiens)


name: LIG3 ligates NEIL1,NEIL2-generated single strand break (Homo sapiens)


name: APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway (Mus musculus)


name: NEIL1,NEIL2 incises DNA strand 5' to the AP site (Mus musculus)


name: LIG3 ligates NEIL1,NEIL2-generated single strand break (Mus musculus)


name: NEIL1,NEIL2 recruits POLB to incised AP site (Mus musculus)


name: LIG3:XRCC1 and PNKP bind NEIL1,NEIL2:POLB:SSB(3'Pi)-gap-dsDNA (Mus musculus)


name: POLB excises the NEIL1,NEIL2-bound AP site (5'dRP) (Mus musculus)


name: NEIL1,NEIL2 displace OGG1 from AP-dsDNA (Mus musculus)


name: POLB incorporates a single nucleotide in place of excised AP residue in NEIL1,NEIL2-mediated AP site resolution (Mus musculus)


name: PNKP hydrolyzes the terminal 3'Pi at the NEIL1,NEIL2-generated single strand break (SSB) (Mus musculus)


name: APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway (Rattus norvegicus)


name: POLB excises the NEIL1,NEIL2-bound AP site (5'dRP) (Rattus norvegicus)


name: LIG3:XRCC1 and PNKP bind NEIL1,NEIL2:POLB:SSB(3'Pi)-gap-dsDNA (Rattus norvegicus)


name: NEIL1,NEIL2 displace OGG1 from AP-dsDNA (Rattus norvegicus)


name: POLB incorporates a single nucleotide in place of excised AP residue in NEIL1,NEIL2-mediated AP site resolution (Rattus norvegicus)


name: PNKP hydrolyzes the terminal 3'Pi at the NEIL1,NEIL2-generated single strand break (SSB) (Rattus norvegicus)


name: NEIL1,NEIL2 recruits POLB to incised AP site (Rattus norvegicus)


name: NEIL1,NEIL2 incises DNA strand 5' to the AP site (Rattus norvegicus)


name: LIG3 ligates NEIL1,NEIL2-generated single strand break (Rattus norvegicus)


name: APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway (Canis familiaris)


name: LIG3 ligates NEIL1,NEIL2-generated single strand break (Canis familiaris)


name: NEIL1,NEIL2 incises DNA strand 5' to the AP site (Canis familiaris)


name: POLB excises the NEIL1,NEIL2-bound AP site (5'dRP) (Canis familiaris)


name: LIG3:XRCC1 and PNKP bind NEIL1,NEIL2:POLB:SSB(3'Pi)-gap-dsDNA (Canis familiaris)


name: NEIL1,NEIL2 recruits POLB to incised AP site (Canis familiaris)


name: NEIL1,NEIL2 displace OGG1 from AP-dsDNA (Canis familiaris)


name: POLB incorporates a single nucleotide in place of excised AP residue in NEIL1,NEIL2-mediated AP site resolution (Canis familiaris)


name: PNKP hydrolyzes the terminal 3'Pi at the NEIL1,NEIL2-generated single strand break (SSB) (Canis familiaris)


name: APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway (Bos taurus)


name: POLB excises the NEIL1,NEIL2-bound AP site (5'dRP) (Bos taurus)


name: LIG3 ligates NEIL1,NEIL2-generated single strand break (Bos taurus)


name: LIG3:XRCC1 and PNKP bind NEIL1,NEIL2:POLB:SSB(3'Pi)-gap-dsDNA (Bos taurus)


name: NEIL1,NEIL2 recruits POLB to incised AP site (Bos taurus)


name: NEIL1,NEIL2 incises DNA strand 5' to the AP site (Bos taurus)


name: NEIL1,NEIL2 displace OGG1 from AP-dsDNA (Bos taurus)


name: POLB incorporates a single nucleotide in place of excised AP residue in NEIL1,NEIL2-mediated AP site resolution (Bos taurus)


name: PNKP hydrolyzes the terminal 3'Pi at the NEIL1,NEIL2-generated single strand break (SSB) (Bos taurus)


name: APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway (Sus scrofa)


name: NEIL1,NEIL2 recruits POLB to incised AP site (Sus scrofa)


name: LIG3:XRCC1 and PNKP bind NEIL1,NEIL2:POLB:SSB(3'Pi)-gap-dsDNA (Sus scrofa)


name: LIG3 ligates NEIL1,NEIL2-generated single strand break (Sus scrofa)


name: NEIL1,NEIL2 incises DNA strand 5' to the AP site (Sus scrofa)


name: PNKP hydrolyzes the terminal 3'Pi at the NEIL1,NEIL2-generated single strand break (SSB) (Sus scrofa)


name: POLB incorporates a single nucleotide in place of excised AP residue in NEIL1,NEIL2-mediated AP site resolution (Sus scrofa)


name: POLB excises the NEIL1,NEIL2-bound AP site (5'dRP) (Sus scrofa)


name: APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway (Danio rerio)


name: LIG3 ligates NEIL1,NEIL2-generated single strand break (Danio rerio)


name: NEIL1,NEIL2 incises DNA strand 5' to the AP site (Danio rerio)


name: POLB excises the NEIL1,NEIL2-bound AP site (5'dRP) (Danio rerio)


name: NEIL1,NEIL2 recruits POLB to incised AP site (Danio rerio)


name: POLB incorporates a single nucleotide in place of excised AP residue in NEIL1,NEIL2-mediated AP site resolution (Danio rerio)


name: PNKP hydrolyzes the terminal 3'Pi at the NEIL1,NEIL2-generated single strand break (SSB) (Danio rerio)


name: APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway (Xenopus tropicalis)


name: POLB excises the NEIL1,NEIL2-bound AP site (5'dRP) (Xenopus tropicalis)


name: NEIL1,NEIL2 recruits POLB to incised AP site (Xenopus tropicalis)


name: POLB incorporates a single nucleotide in place of excised AP residue in NEIL1,NEIL2-mediated AP site resolution (Xenopus tropicalis)


name: PNKP hydrolyzes the terminal 3'Pi at the NEIL1,NEIL2-generated single strand break (SSB) (Xenopus tropicalis)


name: NEIL1,NEIL2 incises DNA strand 5' to the AP site (Xenopus tropicalis)


name: LIG3 ligates NEIL1,NEIL2-generated single strand break (Xenopus tropicalis)


name: APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway (Gallus gallus)


name: NEIL1,NEIL2 incises DNA strand 5' to the AP site (Gallus gallus)


name: APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway (Dictyostelium discoideum)


name: PNKP hydrolyzes the terminal 3'Pi at the NEIL1,NEIL2-generated single strand break (SSB) (Dictyostelium discoideum)


name: POLB incorporates a single nucleotide in place of excised AP residue in NEIL1,NEIL2-mediated AP site resolution (Dictyostelium discoideum)


name: LIG3 ligates NEIL1,NEIL2-generated single strand break (Dictyostelium discoideum)


name: Displacement of DNA glycosylase by APEX1 (Homo sapiens)


name: Displacement of TDG glycosylase by APEX1 at the AP site (Homo sapiens)


name: Displacement of SMUG1 glycosylase by APEX1 at the AP site (Homo sapiens)


name: Displacement of UNG glycosylase by APEX1 at the AP site (Homo sapiens)


name: Displacement of MPG glycosylase by APEX1 at the AP site (Homo sapiens)


name: Displacement of OGG1 glycosylase by APEX1 at the AP site (Homo sapiens)


name: Displacement of MUTYH glycosylase by APEX1 at the AP site (Homo sapiens)


name: Displacement of NTHL1 glycosylase by APEX1 at the AP site (Homo sapiens)


name: Displacement of MBD4 glycosylase by APEX1 at the AP site (Homo sapiens)


name: Displacement of DNA glycosylase by APEX1 (Mus musculus)


name: Displacement of MBD4 glycosylase by APEX1 at the AP site (Mus musculus)


name: Displacement of OGG1 glycosylase by APEX1 at the AP site (Mus musculus)


name: Displacement of MUTYH glycosylase by APEX1 at the AP site (Mus musculus)


name: Displacement of MPG glycosylase by APEX1 at the AP site (Mus musculus)


name: Displacement of UNG glycosylase by APEX1 at the AP site (Mus musculus)


name: Displacement of TDG glycosylase by APEX1 at the AP site (Mus musculus)


name: Displacement of SMUG1 glycosylase by APEX1 at the AP site (Mus musculus)


name: Displacement of NTHL1 glycosylase by APEX1 at the AP site (Mus musculus)


name: Displacement of DNA glycosylase by APEX1 (Rattus norvegicus)


name: Displacement of TDG glycosylase by APEX1 at the AP site (Rattus norvegicus)


name: Displacement of MPG glycosylase by APEX1 at the AP site (Rattus norvegicus)


name: Displacement of UNG glycosylase by APEX1 at the AP site (Rattus norvegicus)


name: Displacement of MUTYH glycosylase by APEX1 at the AP site (Rattus norvegicus)


name: Displacement of OGG1 glycosylase by APEX1 at the AP site (Rattus norvegicus)


name: Displacement of MBD4 glycosylase by APEX1 at the AP site (Rattus norvegicus)


name: Displacement of NTHL1 glycosylase by APEX1 at the AP site (Rattus norvegicus)


name: Displacement of SMUG1 glycosylase by APEX1 at the AP site (Rattus norvegicus)


name: Displacement of DNA glycosylase by APEX1 (Canis familiaris)


name: Displacement of MPG glycosylase by APEX1 at the AP site (Canis familiaris)


name: Displacement of UNG glycosylase by APEX1 at the AP site (Canis familiaris)


name: Displacement of TDG glycosylase by APEX1 at the AP site (Canis familiaris)


name: Displacement of OGG1 glycosylase by APEX1 at the AP site (Canis familiaris)


name: Displacement of MUTYH glycosylase by APEX1 at the AP site (Canis familiaris)


name: Displacement of NTHL1 glycosylase by APEX1 at the AP site (Canis familiaris)


name: Displacement of MBD4 glycosylase by APEX1 at the AP site (Canis familiaris)


name: Displacement of SMUG1 glycosylase by APEX1 at the AP site (Canis familiaris)


name: Displacement of DNA glycosylase by APEX1 (Bos taurus)


name: Displacement of SMUG1 glycosylase by APEX1 at the AP site (Bos taurus)


name: Displacement of MBD4 glycosylase by APEX1 at the AP site (Bos taurus)


name: Displacement of NTHL1 glycosylase by APEX1 at the AP site (Bos taurus)


name: Displacement of MUTYH glycosylase by APEX1 at the AP site (Bos taurus)


name: Displacement of OGG1 glycosylase by APEX1 at the AP site (Bos taurus)


name: Displacement of TDG glycosylase by APEX1 at the AP site (Bos taurus)


name: Displacement of MPG glycosylase by APEX1 at the AP site (Bos taurus)


name: Displacement of DNA glycosylase by APEX1 (Sus scrofa)


name: Displacement of SMUG1 glycosylase by APEX1 at the AP site (Sus scrofa)


name: Displacement of NTHL1 glycosylase by APEX1 at the AP site (Sus scrofa)


name: Displacement of MBD4 glycosylase by APEX1 at the AP site (Sus scrofa)


name: Displacement of MUTYH glycosylase by APEX1 at the AP site (Sus scrofa)


name: Displacement of MPG glycosylase by APEX1 at the AP site (Sus scrofa)


name: Displacement of UNG glycosylase by APEX1 at the AP site (Sus scrofa)


name: Displacement of TDG glycosylase by APEX1 at the AP site (Sus scrofa)


name: Displacement of DNA glycosylase by APEX1 (Danio rerio)


name: Displacement of TDG glycosylase by APEX1 at the AP site (Danio rerio)


name: Displacement of MPG glycosylase by APEX1 at the AP site (Danio rerio)


name: Displacement of UNG glycosylase by APEX1 at the AP site (Danio rerio)


name: Displacement of DNA glycosylase by APEX1 (Xenopus tropicalis)


name: Displacement of TDG glycosylase by APEX1 at the AP site (Xenopus tropicalis)


name: Displacement of UNG glycosylase by APEX1 at the AP site (Xenopus tropicalis)


name: Displacement of MPG glycosylase by APEX1 at the AP site (Xenopus tropicalis)


name: Displacement of MUTYH glycosylase by APEX1 at the AP site (Xenopus tropicalis)


name: Displacement of MBD4 glycosylase by APEX1 at the AP site (Xenopus tropicalis)


name: Displacement of NTHL1 glycosylase by APEX1 at the AP site (Xenopus tropicalis)


name: Displacement of SMUG1 glycosylase by APEX1 at the AP site (Xenopus tropicalis)


name: Displacement of DNA glycosylase by APEX1 (Drosophila melanogaster)


name: Displacement of TDG glycosylase by APEX1 at the AP site (Drosophila melanogaster)


name: Displacement of NTHL1 glycosylase by APEX1 at the AP site (Drosophila melanogaster)


name: Displacement of OGG1 glycosylase by APEX1 at the AP site (Drosophila melanogaster)


name: Displacement of SMUG1 glycosylase by APEX1 at the AP site (Drosophila melanogaster)


name: Displacement of DNA glycosylase by APEX1 (Caenorhabditis elegans)


name: Displacement of NTHL1 glycosylase by APEX1 at the AP site (Caenorhabditis elegans)


name: Displacement of DNA glycosylase by APEX1 (Dictyostelium discoideum)


name: Displacement of MUTYH glycosylase by APEX1 at the AP site (Dictyostelium discoideum)


name: Displacement of OGG1 glycosylase by APEX1 at the AP site (Dictyostelium discoideum)


name: Displacement of NTHL1 glycosylase by APEX1 at the AP site (Dictyostelium discoideum)


name: Displacement of UNG glycosylase by APEX1 at the AP site (Dictyostelium discoideum)


name: Displacement of DNA glycosylase by APEX1 (Plasmodium falciparum)


name: Displacement of UNG glycosylase by APEX1 at the AP site (Plasmodium falciparum)


name: Displacement of NTHL1 glycosylase by APEX1 at the AP site (Plasmodium falciparum)


name: Displacement of OGG1 glycosylase by APEX1 at the AP site (Plasmodium falciparum)


name: Displacement of MUTYH glycosylase by APEX1 at the AP site (Plasmodium falciparum)


name: Displacement of MPG glycosylase by APEX1 at the AP site (Plasmodium falciparum)


name: Resolution of AP sites via the multiple-nucleotide patch replacement pathway (Homo sapiens)


name: Recruitment of POLB to oxidatively damaged AP site (Homo sapiens)


name: Oxidative damage to the AP site (Homo sapiens)


name: POLB incorporates the first 3' dNMP and displaces 5'ddRP at SSB site (Homo sapiens)


name: POLB-Dependent Long Patch Base Excision Repair (Homo sapiens)


name: ADPRHL2 hydrolyses poly(ADP-ribose) (Homo sapiens)


name: PAR-PARP1,PAR-PARP2 dissociate from FEN1 and POLB (Homo sapiens)


name: PARP1,PARP2 dimers bound to FEN1 and POLB autoPARylate (Homo sapiens)


name: POLB-mediated DNA strand displacement synthesis (Homo sapiens)


name: LIG1 bound to POLB ligates SSB (Homo sapiens)


name: LIG1 binds POLB at long-patch BER site (Homo sapiens)


name: PARP1,PARP2 dimers and FEN1 bind POLB and displace APEX1 from damaged AP site (Homo sapiens)


name: LIG1 and POLB dissociate from repaired dsDNA (Homo sapiens)


name: PARG dePARylates PARP1,PARP2 (Homo sapiens)


name: FEN1 bound to POLB cleaves displaced DNA strand (flap) (Homo sapiens)


name: POLB-Dependent Long Patch Base Excision Repair (Mus musculus)


name: LIG1 bound to POLB ligates SSB (Mus musculus)


name: POLB-mediated DNA strand displacement synthesis (Mus musculus)


name: LIG1 binds POLB at long-patch BER site (Mus musculus)


name: PARP1,PARP2 dimers and FEN1 bind POLB and displace APEX1 from damaged AP site (Mus musculus)


name: PARG dePARylates PARP1,PARP2 (Mus musculus)


name: PAR-PARP1,PAR-PARP2 dissociate from FEN1 and POLB (Mus musculus)


name: ADPRHL2 hydrolyses poly(ADP-ribose) (Mus musculus)


name: PARP1,PARP2 dimers bound to FEN1 and POLB autoPARylate (Mus musculus)


name: POLB-Dependent Long Patch Base Excision Repair (Rattus norvegicus)


name: PARP1,PARP2 dimers bound to FEN1 and POLB autoPARylate (Rattus norvegicus)


name: PARP1,PARP2 dimers and FEN1 bind POLB and displace APEX1 from damaged AP site (Rattus norvegicus)


name: ADPRHL2 hydrolyses poly(ADP-ribose) (Rattus norvegicus)


name: LIG1 bound to POLB ligates SSB (Rattus norvegicus)


name: POLB-mediated DNA strand displacement synthesis (Rattus norvegicus)


name: LIG1 binds POLB at long-patch BER site (Rattus norvegicus)


name: PAR-PARP1,PAR-PARP2 dissociate from FEN1 and POLB (Rattus norvegicus)


name: PARG dePARylates PARP1,PARP2 (Rattus norvegicus)


name: POLB-Dependent Long Patch Base Excision Repair (Canis familiaris)


name: LIG1 binds POLB at long-patch BER site (Canis familiaris)


name: PARP1,PARP2 dimers and FEN1 bind POLB and displace APEX1 from damaged AP site (Canis familiaris)


name: PAR-PARP1,PAR-PARP2 dissociate from FEN1 and POLB (Canis familiaris)


name: LIG1 bound to POLB ligates SSB (Canis familiaris)


name: POLB-mediated DNA strand displacement synthesis (Canis familiaris)


name: PARP1,PARP2 dimers bound to FEN1 and POLB autoPARylate (Canis familiaris)


name: POLB-Dependent Long Patch Base Excision Repair (Bos taurus)


name: PARG dePARylates PARP1,PARP2 (Bos taurus)


name: PARP1,PARP2 dimers and FEN1 bind POLB and displace APEX1 from damaged AP site (Bos taurus)


name: LIG1 binds POLB at long-patch BER site (Bos taurus)


name: LIG1 bound to POLB ligates SSB (Bos taurus)


name: POLB-mediated DNA strand displacement synthesis (Bos taurus)


name: PARP1,PARP2 dimers bound to FEN1 and POLB autoPARylate (Bos taurus)


name: ADPRHL2 hydrolyses poly(ADP-ribose) (Bos taurus)


name: PAR-PARP1,PAR-PARP2 dissociate from FEN1 and POLB (Bos taurus)


name: POLB-Dependent Long Patch Base Excision Repair (Sus scrofa)


name: PARP1,PARP2 dimers and FEN1 bind POLB and displace APEX1 from damaged AP site (Sus scrofa)


name: LIG1 binds POLB at long-patch BER site (Sus scrofa)


name: ADPRHL2 hydrolyses poly(ADP-ribose) (Sus scrofa)


name: LIG1 bound to POLB ligates SSB (Sus scrofa)


name: POLB-mediated DNA strand displacement synthesis (Sus scrofa)


name: PARP1,PARP2 dimers bound to FEN1 and POLB autoPARylate (Sus scrofa)


name: PAR-PARP1,PAR-PARP2 dissociate from FEN1 and POLB (Sus scrofa)


name: PARG dePARylates PARP1,PARP2 (Sus scrofa)


name: POLB-Dependent Long Patch Base Excision Repair (Danio rerio)


name: POLB-mediated DNA strand displacement synthesis (Danio rerio)


name: PAR-PARP1,PAR-PARP2 dissociate from FEN1 and POLB (Danio rerio)


name: PARP1,PARP2 dimers and FEN1 bind POLB and displace APEX1 from damaged AP site (Danio rerio)


name: PARP1,PARP2 dimers bound to FEN1 and POLB autoPARylate (Danio rerio)


name: ADPRHL2 hydrolyses poly(ADP-ribose) (Danio rerio)


name: POLB-Dependent Long Patch Base Excision Repair (Xenopus tropicalis)


name: PARP1,PARP2 dimers bound to FEN1 and POLB autoPARylate (Xenopus tropicalis)


name: PARP1,PARP2 dimers and FEN1 bind POLB and displace APEX1 from damaged AP site (Xenopus tropicalis)


name: PARG dePARylates PARP1,PARP2 (Xenopus tropicalis)


name: ADPRHL2 hydrolyses poly(ADP-ribose) (Xenopus tropicalis)


name: POLB-mediated DNA strand displacement synthesis (Xenopus tropicalis)


name: PAR-PARP1,PAR-PARP2 dissociate from FEN1 and POLB (Xenopus tropicalis)


name: POLB-Dependent Long Patch Base Excision Repair (Gallus gallus)


name: ADPRHL2 hydrolyses poly(ADP-ribose) (Gallus gallus)


name: PARG dePARylates PARP1,PARP2 (Gallus gallus)


name: POLB-Dependent Long Patch Base Excision Repair (Drosophila melanogaster)


name: PARG dePARylates PARP1,PARP2 (Drosophila melanogaster)


name: POLB-Dependent Long Patch Base Excision Repair (Dictyostelium discoideum)


name: PARP1,PARP2 dimers and FEN1 bind POLB and displace APEX1 from damaged AP site (Dictyostelium discoideum)


name: LIG1 binds POLB at long-patch BER site (Dictyostelium discoideum)


name: LIG1 bound to POLB ligates SSB (Dictyostelium discoideum)


name: POLB-mediated DNA strand displacement synthesis (Dictyostelium discoideum)


name: PARP1,PARP2 dimers bound to FEN1 and POLB autoPARylate (Dictyostelium discoideum)


name: PAR-PARP1,PAR-PARP2 dissociate from FEN1 and POLB (Dictyostelium discoideum)


name: PARG dePARylates PARP1,PARP2 (Dictyostelium discoideum)


name: PCNA-Dependent Long Patch Base Excision Repair (Homo sapiens)


name: PCNA:POLD,POLE:RPA:RFC and FEN1 bind APEX1 (Homo sapiens)


name: LIG1 bound to APEX1 and PCNA ligates SSB (Homo sapiens)


name: FEN1 bound to PCNA and APEX1 cleaves flap ssDNA (Homo sapiens)


name: LIG1, APEX1 and PCNA:POLD,POLE:RPA:RFC dissociate from repaired DNA (Homo sapiens)


name: LIG1 binds APEX1 and PCNA at SSB (Homo sapiens)


name: POLD,POLE-mediated DNA strand displacement synthesis (Homo sapiens)


name: PCNA-Dependent Long Patch Base Excision Repair (Mus musculus)


name: PCNA:POLD,POLE:RPA:RFC and FEN1 bind APEX1 (Mus musculus)


name: POLD,POLE-mediated DNA strand displacement synthesis (Mus musculus)


name: LIG1 bound to APEX1 and PCNA ligates SSB (Mus musculus)


name: LIG1 binds APEX1 and PCNA at SSB (Mus musculus)


name: PCNA-Dependent Long Patch Base Excision Repair (Rattus norvegicus)


name: POLD,POLE-mediated DNA strand displacement synthesis (Rattus norvegicus)


name: PCNA:POLD,POLE:RPA:RFC and FEN1 bind APEX1 (Rattus norvegicus)


name: LIG1 bound to APEX1 and PCNA ligates SSB (Rattus norvegicus)


name: LIG1 binds APEX1 and PCNA at SSB (Rattus norvegicus)


name: PCNA-Dependent Long Patch Base Excision Repair (Canis familiaris)


name: PCNA:POLD,POLE:RPA:RFC and FEN1 bind APEX1 (Canis familiaris)


name: POLD,POLE-mediated DNA strand displacement synthesis (Canis familiaris)


name: LIG1 bound to APEX1 and PCNA ligates SSB (Canis familiaris)


name: LIG1 binds APEX1 and PCNA at SSB (Canis familiaris)


name: PCNA-Dependent Long Patch Base Excision Repair (Bos taurus)


name: LIG1 binds APEX1 and PCNA at SSB (Bos taurus)


name: PCNA:POLD,POLE:RPA:RFC and FEN1 bind APEX1 (Bos taurus)


name: POLD,POLE-mediated DNA strand displacement synthesis (Bos taurus)


name: LIG1 bound to APEX1 and PCNA ligates SSB (Bos taurus)


name: PCNA-Dependent Long Patch Base Excision Repair (Sus scrofa)


name: LIG1 binds APEX1 and PCNA at SSB (Sus scrofa)


name: PCNA:POLD,POLE:RPA:RFC and FEN1 bind APEX1 (Sus scrofa)


name: POLD,POLE-mediated DNA strand displacement synthesis (Sus scrofa)


name: LIG1 bound to APEX1 and PCNA ligates SSB (Sus scrofa)


name: PCNA-Dependent Long Patch Base Excision Repair (Xenopus tropicalis)


name: POLD,POLE-mediated DNA strand displacement synthesis (Xenopus tropicalis)


name: PCNA:POLD,POLE:RPA:RFC and FEN1 bind APEX1 (Xenopus tropicalis)


name: PCNA-Dependent Long Patch Base Excision Repair (Drosophila melanogaster)


name: POLD,POLE-mediated DNA strand displacement synthesis (Drosophila melanogaster)


name: LIG1 bound to APEX1 and PCNA ligates SSB (Drosophila melanogaster)


name: LIG1 binds APEX1 and PCNA at SSB (Drosophila melanogaster)


name: PCNA-Dependent Long Patch Base Excision Repair (Caenorhabditis elegans)


name: LIG1 bound to APEX1 and PCNA ligates SSB (Caenorhabditis elegans)


name: LIG1 binds APEX1 and PCNA at SSB (Caenorhabditis elegans)


name: POLD,POLE-mediated DNA strand displacement synthesis (Caenorhabditis elegans)


name: PCNA-Dependent Long Patch Base Excision Repair (Dictyostelium discoideum)


name: POLD,POLE-mediated DNA strand displacement synthesis (Dictyostelium discoideum)


name: LIG1 binds APEX1 and PCNA at SSB (Dictyostelium discoideum)


name: PCNA:POLD,POLE:RPA:RFC and FEN1 bind APEX1 (Dictyostelium discoideum)


name: LIG1 bound to APEX1 and PCNA ligates SSB (Dictyostelium discoideum)


name: PCNA-Dependent Long Patch Base Excision Repair (Schizosaccharomyces pombe)


name: LIG1 binds APEX1 and PCNA at SSB (Schizosaccharomyces pombe)


name: LIG1 bound to APEX1 and PCNA ligates SSB (Schizosaccharomyces pombe)


name: POLD,POLE-mediated DNA strand displacement synthesis (Schizosaccharomyces pombe)


name: PCNA-Dependent Long Patch Base Excision Repair (Plasmodium falciparum)


name: POLD,POLE-mediated DNA strand displacement synthesis (Plasmodium falciparum)


name: LIG1 bound to APEX1 and PCNA ligates SSB (Plasmodium falciparum)


name: LIG1 binds APEX1 and PCNA at SSB (Plasmodium falciparum)


name: Resolution of AP sites via the multiple-nucleotide patch replacement pathway (Mus musculus)


name: POLB incorporates the first 3' dNMP and displaces 5'ddRP at SSB site (Mus musculus)


name: Oxidative damage to the AP site (Mus musculus)


name: Recruitment of POLB to oxidatively damaged AP site (Mus musculus)


name: Resolution of AP sites via the multiple-nucleotide patch replacement pathway (Rattus norvegicus)


name: Recruitment of POLB to oxidatively damaged AP site (Rattus norvegicus)


name: Oxidative damage to the AP site (Rattus norvegicus)


name: POLB incorporates the first 3' dNMP and displaces 5'ddRP at SSB site (Rattus norvegicus)


name: Resolution of AP sites via the multiple-nucleotide patch replacement pathway (Canis familiaris)


name: Recruitment of POLB to oxidatively damaged AP site (Canis familiaris)


name: POLB incorporates the first 3' dNMP and displaces 5'ddRP at SSB site (Canis familiaris)


name: Oxidative damage to the AP site (Canis familiaris)


name: Resolution of AP sites via the multiple-nucleotide patch replacement pathway (Bos taurus)


name: Recruitment of POLB to oxidatively damaged AP site (Bos taurus)


name: POLB incorporates the first 3' dNMP and displaces 5'ddRP at SSB site (Bos taurus)


name: Oxidative damage to the AP site (Bos taurus)


name: Resolution of AP sites via the multiple-nucleotide patch replacement pathway (Sus scrofa)


name: Oxidative damage to the AP site (Sus scrofa)


name: POLB incorporates the first 3' dNMP and displaces 5'ddRP at SSB site (Sus scrofa)


name: Recruitment of POLB to oxidatively damaged AP site (Sus scrofa)


name: Resolution of AP sites via the multiple-nucleotide patch replacement pathway (Danio rerio)


name: POLB incorporates the first 3' dNMP and displaces 5'ddRP at SSB site (Danio rerio)


name: Oxidative damage to the AP site (Danio rerio)


name: Recruitment of POLB to oxidatively damaged AP site (Danio rerio)


name: Resolution of AP sites via the multiple-nucleotide patch replacement pathway (Xenopus tropicalis)


name: POLB incorporates the first 3' dNMP and displaces 5'ddRP at SSB site (Xenopus tropicalis)


name: Oxidative damage to the AP site (Xenopus tropicalis)


name: Recruitment of POLB to oxidatively damaged AP site (Xenopus tropicalis)


name: Resolution of AP sites via the multiple-nucleotide patch replacement pathway (Drosophila melanogaster)


name: Oxidative damage to the AP site (Drosophila melanogaster)


name: Resolution of AP sites via the multiple-nucleotide patch replacement pathway (Caenorhabditis elegans)


name: Oxidative damage to the AP site (Caenorhabditis elegans)


name: Resolution of AP sites via the multiple-nucleotide patch replacement pathway (Dictyostelium discoideum)


name: Oxidative damage to the AP site (Dictyostelium discoideum)


name: POLB incorporates the first 3' dNMP and displaces 5'ddRP at SSB site (Dictyostelium discoideum)


name: Recruitment of POLB to oxidatively damaged AP site (Dictyostelium discoideum)


name: Resolution of AP sites via the multiple-nucleotide patch replacement pathway (Plasmodium falciparum)


name: Oxidative damage to the AP site (Plasmodium falciparum)


name: Resolution of AP sites via the single-nucleotide replacement pathway (Homo sapiens)


name: Dissociation of LIG3:XRCC1 complex from the BER site (Homo sapiens)


name: Resynthesis of excised residue by POLB (Homo sapiens)


name: LIG3-mediated DNA ligation via the single-nucleotide replacement pathway (Homo sapiens)


name: Recruitment of LIG3:XRCC1 complex to the site of repair by POLB (Homo sapiens)


name: Abasic sugar-phosphate removal via the single-nucleotide replacement pathway (Homo sapiens)


name: Recruitment of POLB to the AP site (Homo sapiens)


name: Excision of the abasic sugar phosphate (5'dRP) residue at the single strand break (Homo sapiens)


name: Abasic sugar-phosphate removal via the single-nucleotide replacement pathway (Mus musculus)


name: Excision of the abasic sugar phosphate (5'dRP) residue at the single strand break (Mus musculus)


name: Recruitment of POLB to the AP site (Mus musculus)


name: Abasic sugar-phosphate removal via the single-nucleotide replacement pathway (Rattus norvegicus)


name: Recruitment of POLB to the AP site (Rattus norvegicus)


name: Excision of the abasic sugar phosphate (5'dRP) residue at the single strand break (Rattus norvegicus)


name: Abasic sugar-phosphate removal via the single-nucleotide replacement pathway (Canis familiaris)


name: Recruitment of POLB to the AP site (Canis familiaris)


name: Excision of the abasic sugar phosphate (5'dRP) residue at the single strand break (Canis familiaris)


name: Abasic sugar-phosphate removal via the single-nucleotide replacement pathway (Bos taurus)


name: Recruitment of POLB to the AP site (Bos taurus)


name: Excision of the abasic sugar phosphate (5'dRP) residue at the single strand break (Bos taurus)


name: Abasic sugar-phosphate removal via the single-nucleotide replacement pathway (Sus scrofa)


name: Excision of the abasic sugar phosphate (5'dRP) residue at the single strand break (Sus scrofa)


name: Recruitment of POLB to the AP site (Sus scrofa)


name: Abasic sugar-phosphate removal via the single-nucleotide replacement pathway (Danio rerio)


name: Recruitment of POLB to the AP site (Danio rerio)


name: Excision of the abasic sugar phosphate (5'dRP) residue at the single strand break (Danio rerio)


name: Abasic sugar-phosphate removal via the single-nucleotide replacement pathway (Xenopus tropicalis)


name: Excision of the abasic sugar phosphate (5'dRP) residue at the single strand break (Xenopus tropicalis)


name: Recruitment of POLB to the AP site (Xenopus tropicalis)


name: Abasic sugar-phosphate removal via the single-nucleotide replacement pathway (Dictyostelium discoideum)


name: Recruitment of POLB to the AP site (Dictyostelium discoideum)


name: Excision of the abasic sugar phosphate (5'dRP) residue at the single strand break (Dictyostelium discoideum)


name: Resolution of AP sites via the single-nucleotide replacement pathway (Mus musculus)


name: LIG3-mediated DNA ligation via the single-nucleotide replacement pathway (Mus musculus)


name: Recruitment of LIG3:XRCC1 complex to the site of repair by POLB (Mus musculus)


name: Resynthesis of excised residue by POLB (Mus musculus)


name: Resolution of AP sites via the single-nucleotide replacement pathway (Rattus norvegicus)


name: LIG3-mediated DNA ligation via the single-nucleotide replacement pathway (Rattus norvegicus)


name: Recruitment of LIG3:XRCC1 complex to the site of repair by POLB (Rattus norvegicus)


name: Resynthesis of excised residue by POLB (Rattus norvegicus)


name: Resolution of AP sites via the single-nucleotide replacement pathway (Canis familiaris)


name: Resynthesis of excised residue by POLB (Canis familiaris)


name: Recruitment of LIG3:XRCC1 complex to the site of repair by POLB (Canis familiaris)


name: LIG3-mediated DNA ligation via the single-nucleotide replacement pathway (Canis familiaris)


name: Resolution of AP sites via the single-nucleotide replacement pathway (Bos taurus)


name: Recruitment of LIG3:XRCC1 complex to the site of repair by POLB (Bos taurus)


name: Resynthesis of excised residue by POLB (Bos taurus)


name: LIG3-mediated DNA ligation via the single-nucleotide replacement pathway (Bos taurus)


name: Resolution of AP sites via the single-nucleotide replacement pathway (Sus scrofa)


name: Recruitment of LIG3:XRCC1 complex to the site of repair by POLB (Sus scrofa)


name: Resynthesis of excised residue by POLB (Sus scrofa)


name: LIG3-mediated DNA ligation via the single-nucleotide replacement pathway (Sus scrofa)


name: Resolution of AP sites via the single-nucleotide replacement pathway (Xenopus tropicalis)


name: Resynthesis of excised residue by POLB (Xenopus tropicalis)


name: LIG3-mediated DNA ligation via the single-nucleotide replacement pathway (Xenopus tropicalis)


name: Recruitment of LIG3:XRCC1 complex to the site of repair by POLB (Xenopus tropicalis)


name: Resolution of AP sites via the single-nucleotide replacement pathway (Dictyostelium discoideum)


name: LIG3-mediated DNA ligation via the single-nucleotide replacement pathway (Dictyostelium discoideum)


name: Resynthesis of excised residue by POLB (Dictyostelium discoideum)


name: Recruitment of LIG3:XRCC1 complex to the site of repair by POLB (Dictyostelium discoideum)


name: Resolution of Abasic Sites (AP sites) (Mus musculus)


name: APEX1 mediates endonucleolytic cleavage at the 5' side of the AP site (Mus musculus)


name: Resolution of Abasic Sites (AP sites) (Rattus norvegicus)


name: APEX1 mediates endonucleolytic cleavage at the 5' side of the AP site (Rattus norvegicus)


name: Resolution of Abasic Sites (AP sites) (Canis familiaris)


name: APEX1 mediates endonucleolytic cleavage at the 5' side of the AP site (Canis familiaris)


name: Resolution of Abasic Sites (AP sites) (Bos taurus)


name: APEX1 mediates endonucleolytic cleavage at the 5' side of the AP site (Bos taurus)


name: Resolution of Abasic Sites (AP sites) (Sus scrofa)


name: APEX1 mediates endonucleolytic cleavage at the 5' side of the AP site (Sus scrofa)


name: Resolution of Abasic Sites (AP sites) (Danio rerio)


name: APEX1 mediates endonucleolytic cleavage at the 5' side of the AP site (Danio rerio)


name: Resolution of Abasic Sites (AP sites) (Xenopus tropicalis)


name: APEX1 mediates endonucleolytic cleavage at the 5' side of the AP site (Xenopus tropicalis)


name: Resolution of Abasic Sites (AP sites) (Drosophila melanogaster)


name: APEX1 mediates endonucleolytic cleavage at the 5' side of the AP site (Drosophila melanogaster)


name: Resolution of Abasic Sites (AP sites) (Caenorhabditis elegans)


name: APEX1 mediates endonucleolytic cleavage at the 5' side of the AP site (Caenorhabditis elegans)


name: Resolution of Abasic Sites (AP sites) (Dictyostelium discoideum)


name: APEX1 mediates endonucleolytic cleavage at the 5' side of the AP site (Dictyostelium discoideum)


name: Resolution of Abasic Sites (AP sites) (Plasmodium falciparum)


name: APEX1 mediates endonucleolytic cleavage at the 5' side of the AP site (Plasmodium falciparum)


name: Defective OGG1 Substrate Processing (Homo sapiens)


name: Defective OGG1 mutants do not excise FapyG (Homo sapiens)


name: Defective OGG1 mutants do not excise 8-oxoguanine (Homo sapiens)


name: Defective OGG1 Localization (Homo sapiens)


name: OGG1beta G12E does not translocate to mitochondria (Homo sapiens)


name: Defective OGG1 Substrate Binding (Homo sapiens)


name: Defective OGG1 mutants show decreased binding to 8-oxoguanine (Homo sapiens)


name: Defective MUTYH substrate processing (Homo sapiens)


name: Defective MUTYH mutants do not cleave adenine mispaired with 8-oxoguanine (Homo sapiens)


name: Defective MUTYH substrate binding (Homo sapiens)


name: Defective MUTYH mutants do not bind adenine mispaired with 8-oxoguanine (Homo sapiens)


name: Defective Base Excision Repair Associated with NEIL1 (Homo sapiens)


name: NEIL1 Q282TER does not translocate to the nucleus (Homo sapiens)


name: Defective NEIL1 variants do not cleave Tg (Homo sapiens)


name: NEIL1 G83D does not cleave FapyA (Homo sapiens)


name: NEIL1 G83D does not cleave FapyG (Homo sapiens)


name: NEIL1 G83D does not cleave DHU (Homo sapiens)


name: Defective NTHL1 substrate binding (Homo sapiens)


name: Defective NTHL1 truncation mutants do not bind dihydrouracil (DHU) (Homo sapiens)


name: Defective NTHL1 truncation mutants do not bind formamidopyrimidine (FapyA) (Homo sapiens)


name: Defective NTHL1 truncation mutants do not bind cytosine glycol (Cg) (Homo sapiens)


name: Defective NTHL1 truncation mutants do not bind thymine glycol (Tg) (Homo sapiens)


name: Defective NTHL1 substrate processing (Homo sapiens)


name: NTHL1 D239Y does not cleave thymine glycol (Tg) (Homo sapiens)


name: NTHL1 D239Y does not cleave dihydrouracil (DHU) (Homo sapiens)


name: Loss of MECP2 binding ability to the NCoR/SMRT complex (Homo sapiens)


name: MECP2 mutants P302R,K304E,K305R,R306C,(R306H) do not bind NCoR/SMRT complex (Homo sapiens)


name: Loss of MECP2 binding ability to 5mC-DNA (Homo sapiens)


name: MECP2 T158A:SIN3A complex does not bind BDNF gene promoter (Homo sapiens)


name: MECP2 mutants R106W, D121G, R133H, S134F, T158M and T158A do not bind to 5mC-DNA (Homo sapiens)


name: Loss of phosphorylation of MECP2 at T308 (Homo sapiens)


name: Active PKA, CaMK IV do not phosphorylate MECP2 mutants R306C,(R306H) at T308 (Homo sapiens)


name: Loss of MECP2 binding ability to 5hmC-DNA (Homo sapiens)


name: MECP2 mutants R133C ,D121G, R133H and S134F do not bind 5hmC-DNA (Homo sapiens)


name: Defective ABCA12 causes ARCI4B (Homo sapiens)


name: Defective ABCA12 does not transport lipids from cytosol to extracellular region (Homo sapiens)


name: Defective ABCC9 causes CMD10, ATFB12 and Cantu syndrome (Homo sapiens)


name: Defective ABCC9 (in KCNJ11:ABCC9) does not transport K+ from extracellular region to cytosol (Homo sapiens)


name: Defective ABCG8 causes GBD4 and sitosterolemia (Homo sapiens)


name: Defective ABCG8 (in ABCG5:ABCG8) does not transport sterols from cytosol to extracellular region (Homo sapiens)


name: Defective ABCB4 causes PFIC3, ICP3 and GBD1 (Homo sapiens)


name: Defective ABCB4 does not transport PC from plasma membrane to extracellular region (Homo sapiens)


name: Defective ABCA3 causes SMDP3 (Homo sapiens)


name: Defective ABCA3 does not transport PC, PG from ER membrane to lamellar body (Homo sapiens)


name: Defective ABCB11 causes PFIC2 and BRIC2 (Homo sapiens)


name: Defective ABCB11 does not transport bile salts from cytosol to extracellular region (Homo sapiens)


name: Defective ABCG5 causes sitosterolemia (Homo sapiens)


name: Defective ABCG5 (in ABCG5:ABCG8) does not transport sterols from cytosol to extracellular region (Homo sapiens)


name: Defective ABCC2 causes DJS (Homo sapiens)


name: Defective ABCC2 does not transport BMG,BDG from cytosol to extracellular region (Homo sapiens)


name: Defective ABCC6 causes PXE (Homo sapiens)


name: Defective ABCC6 does not transport organic anion from cytosol to extracellular region (Homo sapiens)


name: Defective ABCA1 causes TGD (Homo sapiens)


name: Defective ABCA1 does not transport CHOL from transport vesicle membrane to plasma membrane (Homo sapiens)


name: Defective CFTR causes cystic fibrosis (Homo sapiens)


name: RNF5 and RNF185 ubiquitinate CFTR F508del (Homo sapiens)


name: CFTR F508del binds CFTR correctors (Homo sapiens)


name: CFTR F508del binds components of the ERAD machinery for ubiquitination and degradation (Homo sapiens)


name: Ivacaftor binds CFTR G551D (Homo sapiens)


name: CFTR F508del is degraded by the 26S proteasome (Homo sapiens)


name: Ivacaftor:CFTR G551D transports Cl- from cytosol to extracellular region (Homo sapiens)


name: VCP-catalyzed ATP hydrolysis promotes the translocation of CFTR F508del into the cytosol (Homo sapiens)


name: Defective CFTR does not transport Cl- from cytosol to extracellular region (Homo sapiens)


name: Defective ABCD1 causes ALD (Homo sapiens)


name: Defective ABCD1 does not transfer LCFAs from cytosol to peroxisomal matrix (Homo sapiens)


name: Defective ABCB6 causes MCOPCB7 (Homo sapiens)


name: Defective ABCB6 does not transport porphyrin from cytosol into mitochondria matrix (Homo sapiens)


name: Defective ABCC8 can cause hypo- and hyper-glycemias (Homo sapiens)


name: ATP-activated inward rectifier potassium channel activity

description: Enables the transmembrane transfer of a potassium ion by an inwardly-rectifying voltage-gated channel, where the inward rectification is due to a voltage-dependent block of the channel pore by ATP. An inwardly rectifying current-voltage relation is one where at any given driving force the inward flow of K+ ions exceeds the outward flow for the opposite driving force.


name: Defective ABCC8 does not form functional KATP channels, causing hyperinsulinemic hypoglycemia (Homo sapiens)


name: Integration of energy metabolism (Homo sapiens)


name: Activation of PP2A by Xylulose-5-phosphate (Homo sapiens)


regulation of insulin secretion

category: biolink:BiologicalProcess biolink:Occurrent biolink:OntologyClass biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: Any process that modulates the frequency, rate or extent of the regulated release of insulin.


ATP binding

description: Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.


name: SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) (Homo sapiens)

definition: Inhibition


name: Calcium Influx through Voltage-gated Calcium Channels (Homo sapiens)


name: Transport of Extracellular Glucose to the Cytosol by GLUT1 and GLUT2 (Homo sapiens)


name: Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion (Homo sapiens)


name: Gq alpha:G beta:G gamma dissociates to Gq alpha:GTP and G beta:G gamma (Homo sapiens)


name: FFAR1 binds rosiglitazone (Homo sapiens)

definition: Agonist|Full agonist


name: Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate (Homo sapiens)


name: FFAR1:FFAR1 ligands activate Gq (Homo sapiens)


name: Gq alpha activates Phospholipase C beta (Homo sapiens)


name: Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion (Mus musculus)


name: FFAR1 binds rosiglitazone (Mus musculus)


name: Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate (Mus musculus)


name: FFAR1:FFAR1 ligands activate Gq (Mus musculus)


name: Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion (Rattus norvegicus)


name: FFAR1:FFAR1 ligands activate Gq (Rattus norvegicus)


name: FFAR1 binds rosiglitazone (Rattus norvegicus)


name: Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate (Rattus norvegicus)


name: FFAR1 binds fatty acids (Rattus norvegicus)


name: Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion (Canis familiaris)


name: FFAR1 binds fatty acids (Canis familiaris)


name: FFAR1 binds rosiglitazone (Canis familiaris)


name: Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate (Canis familiaris)


name: FFAR1:FFAR1 ligands activate Gq (Canis familiaris)


name: Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion (Bos taurus)


name: FFAR1:FFAR1 ligands activate Gq (Bos taurus)


name: Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate (Bos taurus)


name: Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion (Sus scrofa)


name: Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate (Sus scrofa)


name: Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion (Drosophila melanogaster)


name: Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate (Drosophila melanogaster)


name: Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion (Dictyostelium discoideum)


name: Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate (Dictyostelium discoideum)


name: Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion (Schizosaccharomyces pombe)


name: Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate (Schizosaccharomyces pombe)


name: Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion (Saccharomyces cerevisiae)


name: Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate (Saccharomyces cerevisiae)


name: Intracellular metabolism of fatty acids regulates insulin secretion (Homo sapiens)


name: CD36 (FAT) translocates palmitate from the extracellular region to the cytosol (Homo sapiens)


palmitoyl-CoA ligase activity

description: Catalysis of the reaction: ATP + palmitic acid + CoA = AMP + diphosphate + palmitoyl-CoA.


name: Intracellular metabolism of fatty acids regulates insulin secretion (Mus musculus)


name: ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell (Mus musculus)


name: CD36 (FAT) translocates palmitate from the extracellular region to the cytosol (Mus musculus)


name: Intracellular metabolism of fatty acids regulates insulin secretion (Rattus norvegicus)


name: CD36 (FAT) translocates palmitate from the extracellular region to the cytosol (Rattus norvegicus)


name: ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell (Rattus norvegicus)


name: Intracellular metabolism of fatty acids regulates insulin secretion (Canis familiaris)


name: ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell (Canis familiaris)


name: CD36 (FAT) translocates palmitate from the extracellular region to the cytosol (Canis familiaris)


name: Intracellular metabolism of fatty acids regulates insulin secretion (Bos taurus)


name: ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell (Bos taurus)


name: CD36 (FAT) translocates palmitate from the extracellular region to the cytosol (Bos taurus)


name: Intracellular metabolism of fatty acids regulates insulin secretion (Sus scrofa)


name: ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell (Sus scrofa)


name: CD36 (FAT) translocates palmitate from the extracellular region to the cytosol (Sus scrofa)


name: Intracellular metabolism of fatty acids regulates insulin secretion (Danio rerio)


name: CD36 (FAT) translocates palmitate from the extracellular region to the cytosol (Danio rerio)


name: ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell (Danio rerio)


name: Intracellular metabolism of fatty acids regulates insulin secretion (Xenopus tropicalis)


name: CD36 (FAT) translocates palmitate from the extracellular region to the cytosol (Xenopus tropicalis)


name: ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell (Xenopus tropicalis)


name: Intracellular metabolism of fatty acids regulates insulin secretion (Drosophila melanogaster)


name: ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell (Drosophila melanogaster)


name: CD36 (FAT) translocates palmitate from the extracellular region to the cytosol (Drosophila melanogaster)


name: Intracellular metabolism of fatty acids regulates insulin secretion (Caenorhabditis elegans)


name: ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell (Caenorhabditis elegans)


name: CD36 (FAT) translocates palmitate from the extracellular region to the cytosol (Caenorhabditis elegans)


name: Intracellular metabolism of fatty acids regulates insulin secretion (Dictyostelium discoideum)


name: CD36 (FAT) translocates palmitate from the extracellular region to the cytosol (Dictyostelium discoideum)


name: Intracellular metabolism of fatty acids regulates insulin secretion (Schizosaccharomyces pombe)


name: ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell (Schizosaccharomyces pombe)


name: Intracellular metabolism of fatty acids regulates insulin secretion (Saccharomyces cerevisiae)


name: ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell (Saccharomyces cerevisiae)


name: Glucagon-like Peptide-1 (GLP1) regulates insulin secretion (Homo sapiens)


name: GLP1R:GLP1 activates G(s) (Homo sapiens)


name: PKA:AKAP79:IQGAP1 complex dissociates to active PKA subunits in response to cAMP (Homo sapiens)


name: G(s):GTP activates Adenylyl cyclase (Homo sapiens)


name: GLP1R binds GLP1R agonists (Homo sapiens)

definition: Agonist


name: RAP1A exchanges GDP for GTP (Homo sapiens)


name: ER calcium channels open in response to activated PKA (Homo sapiens)


name: Potassium voltage-gated channels close in reponse to PKA (Homo sapiens)


name: Activated Adenylyl cyclase synthesizes cyclic AMP (Homo sapiens)


name: Glucagon-like Peptide-1 (GLP1) regulates insulin secretion (Mus musculus)


name: ER calcium channels open in response to activated PKA (Mus musculus)


name: GLP1R binds GLP1R agonists (Mus musculus)


name: Potassium voltage-gated channels close in reponse to PKA (Mus musculus)


name: RAP1A exchanges GDP for GTP (Mus musculus)


name: Glucagon-like Peptide-1 (GLP1) regulates insulin secretion (Rattus norvegicus)


name: GLP1R binds GLP1R agonists (Rattus norvegicus)


name: RAP1A exchanges GDP for GTP (Rattus norvegicus)


name: cAMP activates EPAC2 (Rattus norvegicus)


name: cAMP activates EPAC1 (Rattus norvegicus)


name: ER calcium channels open in response to activated PKA (Rattus norvegicus)


name: Potassium voltage-gated channels close in reponse to PKA (Rattus norvegicus)


name: Glucagon-like Peptide-1 (GLP1) regulates insulin secretion (Canis familiaris)


name: ER calcium channels open in response to activated PKA (Canis familiaris)


name: RAP1A exchanges GDP for GTP (Canis familiaris)


name: GLP1R binds GLP1R agonists (Canis familiaris)


name: Potassium voltage-gated channels close in reponse to PKA (Canis familiaris)


name: Glucagon-like Peptide-1 (GLP1) regulates insulin secretion (Bos taurus)


name: ER calcium channels open in response to activated PKA (Bos taurus)


name: Potassium voltage-gated channels close in reponse to PKA (Bos taurus)


name: RAP1A exchanges GDP for GTP (Bos taurus)


name: Glucagon-like Peptide-1 (GLP1) regulates insulin secretion (Sus scrofa)


name: RAP1A exchanges GDP for GTP (Sus scrofa)


name: ER calcium channels open in response to activated PKA (Sus scrofa)


name: Potassium voltage-gated channels close in reponse to PKA (Sus scrofa)


name: Glucagon-like Peptide-1 (GLP1) regulates insulin secretion (Danio rerio)


name: RAP1A exchanges GDP for GTP (Danio rerio)


name: GLP1R binds GLP1R agonists (Danio rerio)


name: Potassium voltage-gated channels close in reponse to PKA (Danio rerio)


name: Glucagon-like Peptide-1 (GLP1) regulates insulin secretion (Xenopus tropicalis)


name: cAMP activates EPAC1 (Xenopus tropicalis)


name: ER calcium channels open in response to activated PKA (Xenopus tropicalis)


name: RAP1A exchanges GDP for GTP (Xenopus tropicalis)


name: cAMP activates EPAC2 (Xenopus tropicalis)


name: Potassium voltage-gated channels close in reponse to PKA (Xenopus tropicalis)


name: Glucagon-like Peptide-1 (GLP1) regulates insulin secretion (Drosophila melanogaster)


name: cAMP activates EPAC1 (Drosophila melanogaster)


name: Potassium voltage-gated channels close in reponse to PKA (Drosophila melanogaster)


name: ER calcium channels open in response to activated PKA (Drosophila melanogaster)


name: cAMP activates EPAC2 (Drosophila melanogaster)


name: RAP1A exchanges GDP for GTP (Drosophila melanogaster)


name: Glucagon-like Peptide-1 (GLP1) regulates insulin secretion (Caenorhabditis elegans)


name: cAMP activates EPAC2 (Caenorhabditis elegans)


name: cAMP activates EPAC1 (Caenorhabditis elegans)


name: Potassium voltage-gated channels close in reponse to PKA (Caenorhabditis elegans)


name: RAP1A exchanges GDP for GTP (Caenorhabditis elegans)


name: ER calcium channels open in response to activated PKA (Caenorhabditis elegans)


name: Glucagon-like Peptide-1 (GLP1) regulates insulin secretion (Dictyostelium discoideum)


name: cAMP activates EPAC2 (Dictyostelium discoideum)


name: cAMP activates EPAC1 (Dictyostelium discoideum)


name: RAP1A exchanges GDP for GTP (Dictyostelium discoideum)


name: ER calcium channels open in response to activated PKA (Dictyostelium discoideum)


name: Glucagon-like Peptide-1 (GLP1) regulates insulin secretion (Schizosaccharomyces pombe)


name: cAMP activates EPAC2 (Schizosaccharomyces pombe)


name: cAMP activates EPAC1 (Schizosaccharomyces pombe)


name: Glucagon-like Peptide-1 (GLP1) regulates insulin secretion (Saccharomyces cerevisiae)


name: cAMP activates EPAC1 (Saccharomyces cerevisiae)


name: cAMP activates EPAC2 (Saccharomyces cerevisiae)


name: RAP1A exchanges GDP for GTP (Saccharomyces cerevisiae)


name: Glucagon-like Peptide-1 (GLP1) regulates insulin secretion (Plasmodium falciparum)


name: Potassium voltage-gated channels close in reponse to PKA (Plasmodium falciparum)


name: Acetylcholine regulates insulin secretion (Homo sapiens)


name: Muscarinic Acetylcholine Receptor M3 activates Gq (Homo sapiens)


name: Protein kinase C, alpha type phosphorylates MARCKS (Homo sapiens)


name: Acetylcholine binds Muscarinic Acetylcholine Receptor M3 (Homo sapiens)


name: Acetylcholine regulates insulin secretion (Mus musculus)


name: Protein kinase C, alpha type phosphorylates MARCKS (Mus musculus)


name: Acetylcholine regulates insulin secretion (Rattus norvegicus)


name: Protein kinase C, alpha type phosphorylates MARCKS (Rattus norvegicus)


name: Acetylcholine regulates insulin secretion (Canis familiaris)


name: Protein kinase C, alpha type phosphorylates MARCKS (Canis familiaris)


name: Acetylcholine regulates insulin secretion (Bos taurus)


name: Acetylcholine regulates insulin secretion (Sus scrofa)


name: Protein kinase C, alpha type phosphorylates MARCKS (Sus scrofa)


name: Acetylcholine regulates insulin secretion (Drosophila melanogaster)


name: Acetylcholine regulates insulin secretion (Caenorhabditis elegans)


name: Acetylcholine regulates insulin secretion (Dictyostelium discoideum)


name: Acetylcholine regulates insulin secretion (Schizosaccharomyces pombe)


name: Acetylcholine regulates insulin secretion (Saccharomyces cerevisiae)


name: Adrenaline,noradrenaline inhibits insulin secretion (Homo sapiens)


name: Alpha-2A,alpha-2C Adrenergic Receptors activate Gi.Go heterotrimeric G proteins (Homo sapiens)


name: Low conductance potassium channels in pancreatic beta cells open in response to epinephrine (Homo sapiens)


name: L-type Calcium Channels close in pancreatic beta cells (Homo sapiens)


name: G-beta:G-gamma inhibits Adenylate cyclase (Homo sapiens)


name: Gi,Go Heterotrimeric G-protein complex dissociates (Homo sapiens)


name: Alpha-2A,alpha-2C Adrenergic Receptors bind adrenaline or noradrenaline (Homo sapiens)


name: Adrenaline,noradrenaline inhibits insulin secretion (Mus musculus)


name: G-beta:G-gamma inhibits Adenylate cyclase (Mus musculus)


name: Alpha-2A,alpha-2C Adrenergic Receptors bind adrenaline or noradrenaline (Mus musculus)


name: Alpha-2A,alpha-2C Adrenergic Receptors activate Gi.Go heterotrimeric G proteins (Mus musculus)


name: Gi,Go Heterotrimeric G-protein complex dissociates (Mus musculus)


name: Adrenaline,noradrenaline inhibits insulin secretion (Rattus norvegicus)


name: Alpha-2A,alpha-2C Adrenergic Receptors bind adrenaline or noradrenaline (Rattus norvegicus)


name: G-beta:G-gamma inhibits Adenylate cyclase (Rattus norvegicus)


name: Gi,Go Heterotrimeric G-protein complex dissociates (Rattus norvegicus)


name: Alpha-2A,alpha-2C Adrenergic Receptors activate Gi.Go heterotrimeric G proteins (Rattus norvegicus)


name: Adrenaline,noradrenaline inhibits insulin secretion (Canis familiaris)


name: G-beta:G-gamma inhibits Adenylate cyclase (Canis familiaris)


name: Gi,Go Heterotrimeric G-protein complex dissociates (Canis familiaris)


name: Alpha-2A,alpha-2C Adrenergic Receptors activate Gi.Go heterotrimeric G proteins (Canis familiaris)


name: Alpha-2A,alpha-2C Adrenergic Receptors bind adrenaline or noradrenaline (Canis familiaris)


name: Adrenaline,noradrenaline inhibits insulin secretion (Bos taurus)


name: Gi,Go Heterotrimeric G-protein complex dissociates (Bos taurus)


name: Alpha-2A,alpha-2C Adrenergic Receptors activate Gi.Go heterotrimeric G proteins (Bos taurus)


name: G-beta:G-gamma inhibits Adenylate cyclase (Bos taurus)


name: Alpha-2A,alpha-2C Adrenergic Receptors bind adrenaline or noradrenaline (Bos taurus)


name: Adrenaline,noradrenaline inhibits insulin secretion (Sus scrofa)


name: Gi,Go Heterotrimeric G-protein complex dissociates (Sus scrofa)


name: G-beta:G-gamma inhibits Adenylate cyclase (Sus scrofa)


name: Alpha-2A,alpha-2C Adrenergic Receptors bind adrenaline or noradrenaline (Sus scrofa)


name: Alpha-2A,alpha-2C Adrenergic Receptors activate Gi.Go heterotrimeric G proteins (Sus scrofa)


name: Adrenaline,noradrenaline inhibits insulin secretion (Danio rerio)


name: Alpha-2A,alpha-2C Adrenergic Receptors activate Gi.Go heterotrimeric G proteins (Danio rerio)


name: Alpha-2A,alpha-2C Adrenergic Receptors bind adrenaline or noradrenaline (Danio rerio)


name: G-beta:G-gamma inhibits Adenylate cyclase (Danio rerio)


name: Gi,Go Heterotrimeric G-protein complex dissociates (Danio rerio)


name: Adrenaline,noradrenaline inhibits insulin secretion (Xenopus tropicalis)


name: Alpha-2A,alpha-2C Adrenergic Receptors bind adrenaline or noradrenaline (Xenopus tropicalis)


name: G-beta:G-gamma inhibits Adenylate cyclase (Xenopus tropicalis)


name: Gi,Go Heterotrimeric G-protein complex dissociates (Xenopus tropicalis)


name: Alpha-2A,alpha-2C Adrenergic Receptors activate Gi.Go heterotrimeric G proteins (Xenopus tropicalis)


name: Adrenaline,noradrenaline inhibits insulin secretion (Drosophila melanogaster)


name: Alpha-2A,alpha-2C Adrenergic Receptors bind adrenaline or noradrenaline (Drosophila melanogaster)


name: G-beta:G-gamma inhibits Adenylate cyclase (Drosophila melanogaster)


name: Alpha-2A,alpha-2C Adrenergic Receptors activate Gi.Go heterotrimeric G proteins (Drosophila melanogaster)


name: Gi,Go Heterotrimeric G-protein complex dissociates (Drosophila melanogaster)


name: Adrenaline,noradrenaline inhibits insulin secretion (Caenorhabditis elegans)


name: Alpha-2A,alpha-2C Adrenergic Receptors bind adrenaline or noradrenaline (Caenorhabditis elegans)


name: Alpha-2A,alpha-2C Adrenergic Receptors activate Gi.Go heterotrimeric G proteins (Caenorhabditis elegans)


name: Gi,Go Heterotrimeric G-protein complex dissociates (Caenorhabditis elegans)


name: G-beta:G-gamma inhibits Adenylate cyclase (Caenorhabditis elegans)


name: Calcium Influx through Voltage-gated Calcium Channels (Mus musculus)


name: SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) (Mus musculus)


name: Transport of Extracellular Glucose to the Cytosol by GLUT1 and GLUT2 (Mus musculus)


name: KCNJ11 tetramer:ABCC8 tetramer binds 4xATP, closing the channel (Mus musculus)


name: KCNJ11 tetramer:ABCC8 tetramer binds 4xATP, closing the channel (Rattus norvegicus)


name: Calcium Influx through Voltage-gated Calcium Channels (Rattus norvegicus)


name: SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) (Rattus norvegicus)


name: Transport of Extracellular Glucose to the Cytosol by GLUT1 and GLUT2 (Rattus norvegicus)


name: Meglitinides bind ABCC8 (Rattus norvegicus)


name: Meglitinides bind ABCC8 (Canis familiaris)


name: SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) (Canis familiaris)


name: Calcium Influx through Voltage-gated Calcium Channels (Canis familiaris)


name: Transport of Extracellular Glucose to the Cytosol by GLUT1 and GLUT2 (Canis familiaris)


name: KCNJ11 tetramer:ABCC8 tetramer binds 4xATP, closing the channel (Canis familiaris)


name: Calcium Influx through Voltage-gated Calcium Channels (Bos taurus)


name: KCNJ11 tetramer:ABCC8 tetramer binds 4xATP, closing the channel (Bos taurus)


name: SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) (Bos taurus)


name: Transport of Extracellular Glucose to the Cytosol by GLUT1 and GLUT2 (Bos taurus)


name: Calcium Influx through Voltage-gated Calcium Channels (Sus scrofa)


name: KCNJ11 tetramer:ABCC8 tetramer binds 4xATP, closing the channel (Sus scrofa)


name: SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) (Sus scrofa)


name: Transport of Extracellular Glucose to the Cytosol by GLUT1 and GLUT2 (Sus scrofa)


name: Transport of Extracellular Glucose to the Cytosol by GLUT1 and GLUT2 (Danio rerio)


name: KCNJ11 tetramer:ABCC8 tetramer binds 4xATP, closing the channel (Xenopus tropicalis)


name: SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) (Xenopus tropicalis)


name: Transport of Extracellular Glucose to the Cytosol by GLUT1 and GLUT2 (Xenopus tropicalis)


name: Meglitinides bind ABCC8 (Xenopus tropicalis)


name: SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) (Drosophila melanogaster)


name: KCNJ11 tetramer:ABCC8 tetramer binds 4xATP, closing the channel (Drosophila melanogaster)


name: Transport of Extracellular Glucose to the Cytosol by GLUT1 and GLUT2 (Drosophila melanogaster)


name: Calcium Influx through Voltage-gated Calcium Channels (Drosophila melanogaster)


name: Meglitinides bind ABCC8 (Drosophila melanogaster)


name: Transport of Extracellular Glucose to the Cytosol by GLUT1 and GLUT2 (Caenorhabditis elegans)


name: Calcium Influx through Voltage-gated Calcium Channels (Caenorhabditis elegans)


name: Transport of Extracellular Glucose to the Cytosol by GLUT1 and GLUT2 (Dictyostelium discoideum)


name: Transport of Extracellular Glucose to the Cytosol by GLUT1 and GLUT2 (Saccharomyces cerevisiae)


name: Transport of Extracellular Glucose to the Cytosol by GLUT1 and GLUT2 (Plasmodium falciparum)