name: purine deoxyribonucleotide catabolic process

description: The chemical reactions and pathways resulting in the breakdown of purine deoxyribonucleotide, a compound consisting of deoxyribonucleoside (a purine base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.


name: pyrimidine ribonucleoside diphosphate catabolic process

category: biolink:BiologicalProcess biolink:Occurrent biolink:OntologyClass biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: The chemical reactions and pathways resulting in the breakdown of pyrimidine ribonucleoside diphosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with diphosphate on the sugar.


name: purine deoxyribonucleotide metabolic process

description: The chemical reactions and pathways involving purine deoxyribonucleotide, a compound consisting of deoxyribonucleoside (a purine base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.


name: diadenosine pentaphosphate catabolic process

description: The chemical reactions and pathways resulting in the breakdown of diadenosine pentaphosphate.


name: purine nucleoside monophosphate catabolic process

description: The chemical reactions and pathways resulting in the breakdown of purine nucleoside monophosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with phosphate on the sugar.


name: pyrimidine deoxyribonucleoside triphosphate biosynthetic process

description: The chemical reactions and pathways resulting in the formation of pyrimidine deoxyribonucleoside triphosphate, a compound consisting of a pyrimidine base linked to a deoxyribose sugar esterified with triphosphate on the sugar.


'de novo' NAD biosynthetic process

description: The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide (NAD), beginning with the synthesis of tryptophan or aspartate from simpler precursors; biosynthesis may be of either the oxidized form, NAD, or the reduced form, NADH.


name: nucleoside phosphate biosynthetic process

description: The chemical reactions and pathways resulting in the formation of a nucleoside phosphate.


name: glycolytic process from sucrose through glucose and fructose

description: The chemical reactions and pathways resulting in the breakdown of sucrose into pyruvate through both glucose and fructose intermediates, with the concomitant production of a small amount of ATP and the reduction of NAD(P) to NAD(P)H. Glycolysis begins with the metabolism of a carbohydrate to generate products that can enter the pathway and ends with the production of pyruvate. Pyruvate may be converted to acetyl-coenzyme A, ethanol, lactate, or other small molecules.


description: The chemical reactions and pathways involving a 2'-deoxyribonucleotide, a compound consisting of 2'-deoxyribonucleoside (a base linked to a 2'-deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.


name: very long-chain fatty-acyl-CoA metabolic process

description: The chemical reactions and pathways involving very long-chain fatty-acyl-CoAs, any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a very long-chain fatty-acyl group. A very long-chain fatty acid has an aliphatic tail containing more than 22 carbons.


name: bis(5'-nucleosidyl) oligophosphate metabolic process

description: The chemical reactions and pathways involving a bis(5'-nucleosidyl) oligophosphate, a compound formed of two nucleosides joined together through their 5' carbons by a chain of phosphate molecules.


name: pyridine nucleotide biosynthetic process

description: The chemical reactions and pathways resulting in the formation of a pyridine nucleotide, a nucleotide characterized by a pyridine derivative as a nitrogen base.


name: diadenosine triphosphate biosynthetic process

description: The chemical reactions and pathways resulting in the formation of diadenosine triphosphate, a derivative of the nucleoside adenosine with three phosphate groups attached.


purine ribonucleotide interconversion

description: The chemical reactions and pathways by which a purine ribonucleotide is synthesized from another purine ribonucleotide.


name: purine nucleoside diphosphate catabolic process

description: The chemical reactions and pathways resulting in the breakdown of purine nucleoside diphosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with diphosphate on the sugar.


name: pyrimidine nucleoside diphosphate metabolic process

description: The chemical reactions and pathways involving pyrimidine nucleoside diphosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with diphosphate on the sugar.


name: ribonucleoside diphosphate biosynthetic process

description: The chemical reactions and pathways resulting in the formation of a ribonucleoside diphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with diphosphate on the sugar.


name: deoxyribonucleoside triphosphate biosynthetic process

description: The chemical reactions and pathways resulting in the formation of a deoxyribonucleoside triphosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with triphosphate on the sugar.


description: The chemical reactions and pathways by which a pyrimidine deoxyribonucleotide is synthesized from another pyrimidine deoxyribonucleotide.


AMP salvage

description: The chemical reactions and pathways resulting in the formation of adenosine monophosphate (AMP) from derivatives of it (either adenine, ADP or adenosine 3',5'-bisphosphate) without de novo synthesis.


name: ribonucleoside monophosphate catabolic process

description: The chemical reactions and pathways resulting in the breakdown of a ribonucleoside monophosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with phosphate on the sugar.


purine ribonucleotide metabolic process

description: The chemical reactions and pathways involving a purine ribonucleotide, a compound consisting of ribonucleoside (a purine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.


name: pyrimidine ribonucleoside diphosphate biosynthetic process

description: The chemical reactions and pathways resulting in the formation of pyrimidine ribonucleoside diphosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with diphosphate on the sugar.


name: ribonucleoside triphosphate catabolic process

description: The chemical reactions and pathways resulting in the breakdown of a ribonucleoside triphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with triphosphate on the sugar.


name: flavin adenine dinucleotide catabolic process

description: The chemical reactions and pathways resulting in the breakdown of flavin adenine dinucleotide, which acts as a coenzyme or prosthetic group of various flavoprotein oxidoreductase enzymes.


name: pyrimidine ribonucleoside monophosphate biosynthetic process

description: The chemical reactions and pathways resulting in the formation of pyrimidine ribonucleoside monophosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with phosphate on the sugar.


name: bis(molybdopterin guanine dinucleotide)molybdenum metabolic process

description: The chemical reactions and pathways involving bis(molybdopterin guanine dinucleotide)molybdenum.


CMP phosphorylation

description: The process of introducing a phosphate group into CMP, cytidine monophosphate, to produce CDP. Addition of two phosphate groups produces CTP.


name: purine deoxyribonucleoside triphosphate catabolic process

description: The chemical reactions and pathways resulting in the breakdown of purine deoxyribonucleoside triphosphate, a compound consisting of a purine base linked to a deoxyribose sugar esterified with triphosphate on the sugar.


name: pyrimidine nucleoside monophosphate catabolic process

description: The chemical reactions and pathways resulting in the breakdown of pyrimidine nucleoside monophosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with phosphate on the sugar.


name: diadenosine polyphosphate metabolic process

description: The chemical reactions and pathways involving diadenosine polyphosphate, a derivative of the nucleoside adenosine with phosphate groups attached.


name: purine nucleoside diphosphate metabolic process

description: The chemical reactions and pathways involving purine nucleoside diphosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with diphosphate on the sugar.


description: The chemical reactions and pathways resulting in the formation of GDP-alpha-D-mannosylchitobiosyldiphosphodolichol, a substance composed of mannosylchitobiosyldiphosphodolichol in glycosidic linkage with guanosine diphosphate.


name: ribonucleoside triphosphate metabolic process

description: The chemical reactions and pathways involving a ribonucleoside triphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with triphosphate on the sugar.


UMP salvage

description: Any process which produces UMP, uridine monophosphate, from derivatives of it (e.g. cytidine, uridine, cytosine) without de novo synthesis.


name: purine nucleoside bisphosphate metabolic process

description: The chemical reactions and pathways involving a purine nucleoside bisphosphate, a compound consisting of a purine base linked to a deoxyribose or ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar.


name: diadenosine hexaphosphate catabolic process

description: The chemical reactions and pathways resulting in the breakdown of diadenosine hexaphosphate.


name: bis(5'-nucleosidyl) oligophosphate catabolic process

description: The chemical reactions and pathways resulting in the breakdown of a bis(5'-nucleosidyl) oligophosphate, a compound formed of two nucleosides joined together through their 5' carbons by a chain of phosphate molecules.


name: very long-chain fatty-acyl-CoA catabolic process

description: The chemical reactions and pathways resulting in the breakdown of very long-chain fatty-acyl-CoAs, any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a very long-chain fatty-acyl group. A very long-chain fatty acid has an aliphatic tail containing more than 22 carbons.


glycolytic process from sucrose

description: The chemical reactions and pathways resulting in the breakdown of a sucrose into pyruvate, with the concomitant production of a small amount of ATP and the reduction of NAD(P) to NAD(P)H. Glycolysis begins with the metabolism of a carbohydrate to generate products that can enter the pathway and ends with the production of pyruvate. Pyruvate may be converted to acetyl-coenzyme A, ethanol, lactate, or other small molecules.


cyclic nucleotide catabolic process

description: The chemical reactions and pathways resulting in the breakdown of a cyclic nucleotide, a nucleotide in which the phosphate group is in diester linkage to two positions on the sugar residue.


AMP phosphorylation

description: The process of introducing a phosphate group into AMP, adenosine monophosphate, to produce ADP. Addition of two phosphate groups produces ATP.


name: glycolytic process via Entner-Doudoroff Pathway

description: A glycolytic process in which the glucose is catabolized to pyruvate by first entering the Entner-Doudoroff pathway to yield pyruvate and glyceraldehyde-3-phosphate. The glyceraldehyde-3-phosphate is subsequently converted to pyruvate by the core glycolytic enzymes.


pyrimidine nucleotide interconversion

description: The chemical reactions and pathways by which a pyrimidine nucleotide is synthesized from another pyrimidine nucleotide.


name: 'de novo' NAD biosynthetic process from aspartate

description: The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide (NAD), beginning with the synthesis of aspartate from simpler precursors; biosynthesis may be of either the oxidized form, NAD, or the reduced form, NADH.


name: diadenosine pentaphosphate metabolic process

description: The chemical reactions and pathways involving diadenosine pentaphosphate.


glycolytic process from galactose

description: The chemical reactions and pathways resulting in the breakdown of galactose into pyruvate, with the concomitant production of a small amount of ATP.


ribonucleotide metabolic process

description: The chemical reactions and pathways involving a ribonucleotide, a compound consisting of ribonucleoside (a base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.


ribonucleotide biosynthetic process

description: The chemical reactions and pathways resulting in the formation of a ribonucleotide, a compound consisting of ribonucleoside (a base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.


name: purine deoxyribonucleoside diphosphate metabolic process

description: The chemical reactions and pathways involving purine deoxyribonucleoside diphosphate, a compound consisting of a purine base linked to a deoxyribose sugar esterified with diphosphate on the sugar.


CTP salvage

description: Any process which produces cytidine 5'-triphosphate (CTP) from derivatives of it, without de novo synthesis.


name: purine ribonucleoside bisphosphate biosynthetic process

description: The chemical reactions and pathways resulting in the formation of a purine ribonucleoside bisphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar.


nucleotide biosynthetic process

description: The chemical reactions and pathways resulting in the formation of nucleotides, any nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the glycose moiety; may be mono-, di- or triphosphate; this definition includes cyclic-nucleotides (nucleoside cyclic phosphates).


name: pyrimidine nucleoside triphosphate catabolic process

description: The chemical reactions and pathways resulting in the breakdown of pyrimidine nucleoside triphosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with triphosphate on the sugar.


name: nicotinamide nucleotide metabolic process

description: The chemical reactions and pathways involving nicotinamide nucleotides, any nucleotide that contains combined nicotinamide.


name: pyrimidine ribonucleotide biosynthetic process

description: The chemical reactions and pathways resulting in the formation of a pyrimidine ribonucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.


purine nucleotide interconversion

description: The chemical reactions and pathways by which a purine nucleotide is synthesized from another purine nucleotide.


name: diadenosine tetraphosphate biosynthetic process

description: The chemical reactions and pathways resulting in the formation of diadenosine tetraphosphate, a derivative of the nucleoside adenosine with four phosphate groups attached.


nicotinate nucleotide metabolic process

description: The chemical reactions and pathways involving nicotinamide nucleotides, any nucleotide that contains combined nicotinate (pyridine 3-carboxylic acid, or niacin).


ribonucleotide catabolic process

description: The chemical reactions and pathways resulting in the breakdown of a ribonucleotide, a compound consisting of ribonucleoside (a base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.


name: purine nucleoside monophosphate metabolic process

description: The chemical reactions and pathways involving purine nucleoside monophosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with phosphate on the sugar.


name: pyrimidine deoxyribonucleoside monophosphate metabolic process

description: The chemical reactions and pathways involving pyrimidine deoxynucleoside monophosphate, a compound consisting of a pyrimidine base linked to a deoxyribose sugar esterified with phosphate on the sugar.


'de novo' UMP biosynthetic process

description: The chemical reactions and pathways resulting in the formation of UMP, uridine monophosphate, starting with the synthesis of (S)-dihydroorotate from bicarbonate; UMP biosynthesis may either occur via reduction by quinone, NAD+ or oxygen.


name: diadenosine triphosphate catabolic process

description: The chemical reactions and pathways resulting in the breakdown of diadenosine triphosphate, a derivative of the nucleoside adenosine with three phosphate groups attached.


name: purine ribonucleoside bisphosphate catabolic process

description: The chemical reactions and pathways resulting in the breakdown of a purine ribonucleoside bisphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar.


name: ribonucleoside diphosphate catabolic process

description: The chemical reactions and pathways resulting in the breakdown of a ribonucleoside diphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with diphosphate on the sugar.


name: glycolytic process through glucose-1-phosphate

description: The chemical reactions and pathways through a glucose-1-phosphate intermediate that result in the catabolism of a carbohydrate into pyruvate, with the concomitant production of a small amount of ATP.


purine ribonucleotide catabolic process

description: The chemical reactions and pathways resulting in the breakdown of a purine ribonucleotide, a compound consisting of ribonucleoside (a purine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.


name: deoxyribonucleoside monophosphate catabolic process

description: The chemical reactions and pathways resulting in the breakdown of a deoxyribonucleoside monophosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with phosphate on the sugar.


name: deoxyribonucleoside triphosphate catabolic process

description: The chemical reactions and pathways resulting in the breakdown of a deoxyribonucleoside triphosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with triphosphate on the sugar.


name: deoxyribonucleoside monophosphate biosynthetic process

description: The chemical reactions and pathways resulting in the formation of a deoxyribonucleoside monophosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with phosphate on the sugar.


name: pyrimidine deoxyribonucleoside triphosphate metabolic process

description: The chemical reactions and pathways involving pyrimidine deoxyribonucleoside triphosphate, a compound consisting of a pyrimidine base linked to a deoxyribose sugar esterified with triphosphate on the sugar.


name: pyrimidine nucleoside triphosphate metabolic process

description: The chemical reactions and pathways involving pyrimidine nucleoside triphosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with triphosphate on the sugar.


name: pyrimidine nucleoside triphosphate biosynthetic process

description: The chemical reactions and pathways resulting in the formation of pyrimidine nucleoside triphosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with triphosphate on the sugar.


name: ribonucleoside monophosphate biosynthetic process

description: The chemical reactions and pathways resulting in the formation of a ribonucleoside monophosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with phosphate on the sugar.


pyrimidine nucleotide catabolic process

description: The chemical reactions and pathways resulting in the breakdown of a pyrimidine nucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.


name: purine deoxyribonucleoside diphosphate catabolic process

description: The chemical reactions and pathways resulting in the breakdown of purine deoxyribonucleoside diphosphate, a compound consisting of a purine base linked to a deoxyribose sugar esterified with diphosphate on the sugar.


name: flavin adenine dinucleotide biosynthetic process

description: The chemical reactions and pathways resulting in the formation of flavin adenine dinucleotide, which acts as a coenzyme or prosthetic group of various flavoprotein oxidoreductase enzymes.


name: nucleoside bisphosphate metabolic process

description: The chemical reactions and pathways involving a nucleoside bisphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar.


name: purine deoxyribonucleoside monophosphate biosynthetic process

description: The chemical reactions and pathways resulting in the formation of purine deoxyribonucleoside monophosphate, a compound consisting of a purine base linked to a deoxyribose sugar esterified with phosphate on the sugar.


CMP salvage

description: Any process that generates CMP, cytidine monophosphate, from derivatives of it without de novo synthesis.


name: pyrimidine ribonucleoside monophosphate metabolic process

description: The chemical reactions and pathways involving pyrimidine ribonucleoside monophosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with phosphate on the sugar.


name: pyrimidine ribonucleoside triphosphate metabolic process

description: The chemical reactions and pathways involving pyrimidine ribonucleoside triphosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with triphosphate on the sugar.


name: ribonucleoside bisphosphate catabolic process

description: The chemical reactions and pathways resulting in the breakdown of a ribonucleoside bisphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar.


name: nucleoside bisphosphate catabolic process

description: The chemical reactions and pathways resulting in the breakdown of a nucleoside bisphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar.


name: purine nucleoside diphosphate biosynthetic process

description: The chemical reactions and pathways resulting in the formation of purine nucleoside diphosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with diphosphate on the sugar.


pyridine nucleotide metabolic process

description: The chemical reactions and pathways involving a pyridine nucleotide, a nucleotide characterized by a pyridine derivative as a nitrogen base.


name: purine ribonucleoside monophosphate catabolic process

description: The chemical reactions and pathways resulting in the breakdown of purine ribonucleoside monophosphate, a compound consisting of a purine base linked to a ribose sugar esterified with phosphate on the sugar.


nicotinate nucleotide salvage

description: The generation of nicotinate nucleotide without de novo synthesis.


name: diadenosine tetraphosphate catabolic process

description: The chemical reactions and pathways resulting in the breakdown of diadenosine tetraphosphate, a derivative of the nucleoside adenosine with four phosphate groups attached.


name: glycolytic process through fructose-6-phosphate

description: The chemical reactions and pathways resulting in the breakdown of a monosaccharide into pyruvate, occurring through a fructose-6-phosphate intermediate, with the concomitant production of ATP and NADH.


name: diadenosine tetraphosphate metabolic process

description: The chemical reactions and pathways involving diadenosine tetraphosphate, a derivative of the nucleoside adenosine with four phosphate groups attached.


name: nicotinamide nucleotide biosynthetic process from niacinamide

description: The chemical reactions and pathways resulting in the formation of nicotinamide nucleotide from other compounds, including niacinamide.


name: cyclic purine nucleotide metabolic process

description: The chemical reactions and pathways involving a cyclic nucleotide, a nucleotide in which the phosphate group is in diester linkage to two positions on the sugar residue and the base is a purine.


dTDP-rhamnose biosynthetic process

description: The chemical reactions and pathways resulting in the formation of dTDP-rhamnose, a substance composed of rhamnose in glycosidic linkage with deoxyribosylthymine diphosphate.


name: glycolytic process from fructose through fructose-6-phosphate

description: The glycolytic process through fructose-6-phosphate in which fructose is catabolized into pyruvate.


NAD biosynthetic process

description: The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide, a coenzyme present in most living cells and derived from the B vitamin nicotinic acid; biosynthesis may be of either the oxidized form, NAD, or the reduced form, NADH.


name: pyrimidine nucleotide biosynthetic process

description: The chemical reactions and pathways resulting in the formation of a pyrimidine nucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.


nucleotide metabolic process

description: The chemical reactions and pathways involving a nucleotide, a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the glycose moiety; may be mono-, di- or triphosphate; this definition includes cyclic nucleotides (nucleoside cyclic phosphates).


name: medium-chain fatty-acyl-CoA catabolic process

description: The chemical reactions and pathways resulting in the breakdown of medium-chain fatty-acyl-CoAs, any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a medium-chain fatty-acyl group. A medium-chain fatty acid has an aliphatic tail containing 6 to 12 carbons.


name: diadenosine hexaphosphate metabolic process

description: The chemical reactions and pathways involving diadenosine hexaphosphate.


description: The chemical reactions and pathways by which a purine deoxyribonucleotide is synthesized from another purine deoxyribonucleotide.


pyridine nucleotide salvage

description: Any process that generates a pyridine nucleotide, a nucleotide characterized by a pyridine derivative as a nitrogen base, from derivatives of them without de novo synthesis.


name: nucleoside bisphosphate biosynthetic process

description: The chemical reactions and pathways resulting in the formation of a nucleoside bisphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar.


dAMP phosphorylation

description: The process of introducing a phosphate group into dAMP, deoxyadenosine monophosphate, to produce dADP. Addition of two phosphate groups produces dATP.


IMP salvage

description: Any process which produces inosine monophosphate from derivatives of it, without de novo synthesis.


deoxyribonucleotide metabolic process

description: The chemical reactions and pathways involving a deoxyribonucleotide, a compound consisting of deoxyribonucleoside (a base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.


name: pyrimidine deoxyribonucleotide catabolic process

description: The chemical reactions and pathways resulting in the breakdown of a pyrimidine deoxyribonucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.


name: purine deoxyribonucleoside triphosphate biosynthetic process

description: The chemical reactions and pathways resulting in the formation of purine deoxyribonucleoside triphosphate, a compound consisting of a purine base linked to a deoxyribose sugar esterified with triphosphate on the sugar.


name: purine ribonucleoside triphosphate metabolic process

description: The chemical reactions and pathways involving purine ribonucleoside triphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with triphosphate on the sugar.


XMP salvage

description: Any process which produces xanthosine monophosphate from derivatives of it, without de novo synthesis.


name: pyrimidine nucleoside diphosphate catabolic process

description: The chemical reactions and pathways resulting in the breakdown of pyrimidine nucleoside diphosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with diphosphate on the sugar.


name: glycolysis from storage polysaccharide through glucose-1-phosphate

description: The chemical reactions and pathways resulting in the breakdown of a storage polysaccharide into pyruvate through a glucose-1-phosphate intermediate, with the concomitant production of a small amount of ATP and the reduction of NAD to NADH.


name: purine deoxyribonucleoside monophosphate metabolic process

description: The chemical reactions and pathways involving purine deoxyribonucleoside monophosphate, a compound consisting of a purine base linked to a deoxyribose sugar esterified with phosphate on the sugar.


pyridine nucleotide catabolic process

description: The chemical reactions and pathways resulting in the breakdown of a pyridine nucleotide, a nucleotide characterized by a pyridine derivative as a nitrogen base.


name: pyrimidine ribonucleotide catabolic process

description: The chemical reactions and pathways resulting in the breakdown of a pyrimidine ribonucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.


name: pyrimidine deoxyribonucleoside diphosphate biosynthetic process

description: The chemical reactions and pathways resulting in the formation of pyrimidine deoxyribonucleoside diphosphate, a compound consisting of a pyrimidine base linked to a deoxyribose sugar esterified with diphosphate on the sugar.


cyclic nucleotide biosynthetic process

description: The chemical reactions and pathways resulting in the formation of a cyclic nucleotide, a nucleotide in which the phosphate group is in diester linkage to two positions on the sugar residue.


name: pyrimidine deoxyribonucleoside diphosphate metabolic process

description: The chemical reactions and pathways involving pyrimidine deoxynucleoside diphosphate, a compound consisting of a pyrimidine base linked to a deoxyribose sugar esterified with diphosphate on the sugar.


name: ribonucleoside diphosphate metabolic process

description: The chemical reactions and pathways involving a ribonucleoside diphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with diphosphate on the sugar.


GMP salvage

description: Any process which produces guanosine monophosphate from derivatives of it, without de novo synthesis.


name: guanine deglycation, methylglyoxal removal

description: The removal of methylglyoxal from a glycated guanine, to form lactate and a deglycated guanine.


nucleotide catabolic process

description: The chemical reactions and pathways resulting in the breakdown of nucleotides, any nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the glycose moiety; may be mono-, di- or triphosphate; this definition includes cyclic-nucleotides (nucleoside cyclic phosphates).


name: pyrimidine deoxyribonucleotide metabolic process

description: The chemical reactions and pathways involving a pyrimidine deoxynucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.


name: medium-chain fatty-acyl-CoA metabolic process

description: The chemical reactions and pathways involving medium-chain fatty-acyl-CoAs, any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a long-chain fatty-acyl group. A medium-chain fatty acid has an aliphatic tail containing 6 to 12 carbons.


description: The chemical reactions and pathways involving GDP-alpha-D-mannosylchitobiosyldiphosphodolichol, a substance composed of mannosylchitobiosyldiphosphodolichol in glycosidic linkage with guanosine diphosphate.


name: purine nucleoside triphosphate catabolic process

description: The chemical reactions and pathways resulting in the breakdown of purine nucleoside triphosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with triphosphate on the sugar.


name: diadenosine polyphosphate catabolic process

description: The chemical reactions and pathways resulting in the breakdown of diadenosine polyphosphate, a derivative of the nucleoside adenosine with phosphate groups attached.


purine nucleotide biosynthetic process

description: The chemical reactions and pathways resulting in the formation of a purine nucleotide, a compound consisting of nucleoside (a purine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.


NAD salvage

description: Any process that generates nicotinamide adenine dinucleotide (NAD) from derivatives of it, without de novo synthesis; salvage is usually from the degradation products nicotinic acid (Na) and nicotinamide (Nam).


name: purine nucleoside triphosphate biosynthetic process

description: The chemical reactions and pathways resulting in the formation of purine nucleoside triphosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with triphosphate on the sugar.


name: pyrimidine deoxyribonucleoside monophosphate biosynthetic process

description: The chemical reactions and pathways resulting in the formation of pyrimidine deoxynucleoside monophosphate, a compound consisting of a pyrimidine base linked to a deoxyribose sugar esterified with phosphate on the sugar.


name: pyrimidine ribonucleoside triphosphate catabolic process

description: The chemical reactions and pathways resulting in the breakdown of pyrimidine ribonucleoside triphosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with triphosphate on the sugar.


name: pyrimidine ribonucleoside diphosphate metabolic process

description: The chemical reactions and pathways involving pyrimidine ribonucleoside diphosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with diphosphate on the sugar.


name: ribonucleoside monophosphate metabolic process

description: The chemical reactions and pathways involving a ribonucleoside monophosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with phosphate on the sugar.


name: ribonucleoside bisphosphate biosynthetic process

description: The chemical reactions and pathways resulting in the formation of a ribonucleoside bisphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar.


name: 'de novo' NAD biosynthetic process from tryptophan

description: The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide (NAD), beginning with the synthesis of tryptophan from simpler precursors; biosynthesis may be of either the oxidized form, NAD, or the reduced form, NADH.


pyrimidine ribonucleotide salvage

description: The pathway by which pyrimidine bases or pyrimidine ribonucleosides from pyrimidine nucleotide breakdown are converted back to pyrimidine ribonucleotides. The salvage pathway is important where there is no de novo pyrimidine nucleotide biosynthesis.


dTDP-mannose biosynthetic process

description: The chemical reactions and pathways resulting in the formation of dTDP-mannose, a substance composed of mannose in glycosidic linkage with deoxyribosylthymine diphosphate.


name: purine ribonucleoside diphosphate catabolic process

description: The chemical reactions and pathways resulting in the breakdown of purine ribonucleoside diphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with diphosphate on the sugar.


name: deoxyribonucleoside diphosphate catabolic process

description: The chemical reactions and pathways resulting in the breakdown of a deoxyribonucleoside diphosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with diphosphate on the sugar.


name: purine nucleoside bisphosphate catabolic process

description: The chemical reactions and pathways resulting in the breakdown of a purine nucleoside bisphosphate, a compound consisting of a purine base linked to a deoxyribose or ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar.


dTDP-mannose metabolic process

description: The chemical reactions and pathways involving dTDP-mannose, a substance composed of mannose in glycosidic linkage with deoxyribosylthymine diphosphate.


name: ribonucleoside bisphosphate metabolic process

description: The chemical reactions and pathways involving a ribonucleoside bisphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar.


cyclic nucleotide metabolic process

description: The chemical reactions and pathways involving a cyclic nucleotide, a nucleotide in which the phosphate group is in diester linkage to two positions on the sugar residue.


pyrimidine nucleotide salvage

description: Any process which produces a pyrimidine nucleotide from derivatives of it, without de novo synthesis.


name: nicotinamide nucleotide biosynthetic process

description: The chemical reactions and pathways resulting in the formation of nicotinamide nucleotides, any nucleotide that contains combined nicotinamide.


glycolytic process from glycerol

description: The glycolytic process in which glycerol is catabolized to pyruvate generating ATP and NADH.


name: nicotinate nucleotide biosynthetic process from tryptophan

description: The chemical reactions and pathways resulting in the formation of nicotinate nucleotide from other compounds, including tryptophan.


dTDP-rhamnose metabolic process

description: The chemical reactions and pathways involving dTDP-rhamnose, a substance composed of rhamnose in glycosidic linkage with deoxyribosylthymine diphosphate.


guanine deglycation

description: The removal of a sugar or dicarbonyl from a glycated guanine.


dCMP phosphorylation

description: The process of introducing a phosphate group into dCMP, deoxycytidine monophosphate, to produce dCDP. Addition of two phosphate groups produces dCTP.


GDP-mannose metabolic process

description: The chemical reactions and pathways involving GDP-mannose, a substance composed of mannose in glycosidic linkage with guanosine diphosphate.


description: The process of introducing one or more phosphate groups into a nucleoside monophosphate to produce a polyphosphorylated nucleoside.


name: pyrimidine nucleoside diphosphate biosynthetic process

description: The chemical reactions and pathways resulting in the formation of pyrimidine nucleoside diphosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with diphosphate on the sugar.


name: purine deoxyribonucleoside monophosphate catabolic process

description: The chemical reactions and pathways resulting in the breakdown of purine deoxyribonucleoside monophosphate, a compound consisting of a purine base linked to a deoxyribose sugar esterified with phosphate on the sugar.


nucleoside phosphate catabolic process

description: The chemical reactions and pathways resulting in the breakdown of a nucleoside phosphate.


name: purine ribonucleoside triphosphate biosynthetic process

description: The chemical reactions and pathways resulting in the formation of purine ribonucleoside triphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with triphosphate on the sugar.


name: pyrimidine deoxyribonucleoside triphosphate catabolic process

description: The chemical reactions and pathways resulting in the breakdown of pyrimidine deoxyribonucleoside triphosphate, a compound consisting of a pyrimidine base linked to a deoxyribose sugar esterified with triphosphate on the sugar.


name: purine ribonucleoside diphosphate metabolic process

description: The chemical reactions and pathways involving purine ribonucleoside diphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with diphosphate on the sugar.


name: purine ribonucleoside monophosphate metabolic process

description: The chemical reactions and pathways involving purine ribonucleoside monophosphate, a compound consisting of a purine base linked to a ribose sugar esterified with phosphate on the sugar.


CMP biosynthetic process

description: The chemical reactions and pathways resulting in the formation of CMP, cytidine monophosphate.


name: transport-coupled glycolytic process through glucose-6-phosphate

description: The chemical reactions and pathways resulting in the breakdown of glucose into pyruvate, in which the glucose is converted to glucose-6-phosphate intermediate coupled to transmembrane transport.


description: The chemical reactions and pathways by which a pyrimidine ribonucleotide is synthesized from another pyrimidine ribonucleotide.


name: pyrimidine nucleoside monophosphate metabolic process

description: The chemical reactions and pathways involving pyrimidine nucleoside monophosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with phosphate on the sugar.


name: pyrimidine deoxyribonucleoside diphosphate catabolic process

description: The chemical reactions and pathways resulting in the breakdown of pyrimidine deoxynucleoside diphosphate, a compound consisting of a pyrimidine base linked to a deoxyribose sugar esterified with diphosphate on the sugar.


name: purine ribonucleotide biosynthetic process

description: The chemical reactions and pathways resulting in the formation of a purine ribonucleotide, a compound consisting of ribonucleoside (a purine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.


name: purine ribonucleoside triphosphate catabolic process

description: The chemical reactions and pathways resulting in the breakdown of purine ribonucleoside triphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with triphosphate on the sugar.


name: bis(5'-nucleosidyl) oligophosphate biosynthetic process

description: The chemical reactions and pathways resulting in the formation of a bis(5'-nucleosidyl) oligophosphate, a compound formed of two nucleosides joined together through their 5' carbons by a chain of phosphate molecules.


nucleotide-sugar metabolic process

description: The cellular chemical reactions and pathways involving nucleotide-sugars, any nucleotide-carbohydrate in which the distal phosphoric residue of a nucleoside 5'-diphosphate is in glycosidic linkage with a monosaccharide or monosaccharide derivative.


name: glycolytic process through fructose-1-phosphate

description: The chemical reactions and pathways resulting in the breakdown of fructose into pyruvate through a fructose-1-phosphate intermediate, with the concomitant production of ATP and NADH.


histone serotonyltransferase activity

category: biolink:MolecularActivity biolink:Occurrent biolink:OntologyClass biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: Catalysis of the reaction: L-glutaminyl-[histone] + serotonin = 5-serotonyl-L-glutamyl-[histone] + NH4(+).


peptide serotonyltransferase activity

description: Catalysis of the reaction: L-glutaminyl-[protein] + serotonin = 5-serotonyl-L-glutamyl-[protein] + NH4(+).


The (1S,2R,1'S,2'R)-diastereoisomer of doxacurium.


name: PA_I77A4 Polymerase acidic protein (sprot)

description: An influenza A virus polymerase acidic protein that is encoded in the genome of the H3N2 strain A/Swine/Colorado/1/1977.


name: YQ59_CAEEL Uncharacterized protein C16C10.9 (sprot)

description: A protein that is a translation product of the C16C10.9 gene in worm.


name: RN170_MOUSE E3 ubiquitin-protein ligase RNF170 (sprot)

description: An E3 ubiquitin-protein ligase RNF170 that is encoded in the genome of mouse.


name: E3 ubiquitin-protein ligase RNF170 isoform m3 (mouse)

description: An E3 ubiquitin-protein ligase RNF170 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8CBG9-3.


name: E3 ubiquitin-protein ligase RNF170 isoform m5 (mouse)

description: An E3 ubiquitin-protein ligase RNF170 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8CBG9-5.


name: E3 ubiquitin-protein ligase RNF170 isoform m1 (mouse)

description: An E3 ubiquitin-protein ligase RNF170 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8CBG9-1.


name: E3 ubiquitin-protein ligase RNF170 isoform m2 (mouse)

description: An E3 ubiquitin-protein ligase RNF170 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8CBG9-2.


name: E3 ubiquitin-protein ligase RNF170 isoform m4 (mouse)

description: An E3 ubiquitin-protein ligase RNF170 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8CBG9-4.


GDP biosynthetic process

description: The chemical reactions and pathways resulting in the formation of GDP, guanosine 5'-diphosphate.


GDP metabolic process

description: The chemical reactions and pathways involving GDP, guanosine 5'-diphosphate.


GDP catabolic process

description: The chemical reactions and pathways resulting in the breakdown of GDP, guanosine 5'-diphosphate.


name: beta-microseminoprotein isoform hPSP94 (human)

description: A beta-microseminoprotein (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P08118-1.


name: mothers against decapentaplegic homolog 4 sequence variant Q249* (human)

description: A mothers against decapentaplegic homolog 4 (human) that has has been truncated after the position equivalent to Gln-248 of the amino acid sequence represented by UniProtKB:Q13485. UniProtKB:Q13485, 1-248.


name: SPO77_YEAST Sporulation-specific protein 77 (sprot)

description: A protein that is a translation product of the SPO77 gene in yeast.


name: E3 ubiquitin-protein ligase RNF6 deaminated 1 (human)

description: An E3 ubiquitin-protein ligase RNF6 (human) that has been deaminated on the residue at the position equivalent to Gln-187 of the amino acid sequence represented by UniProtKB:Q9Y252-1. Example: UniProtKB:Q9Y252-1, Gln-187, MOD:00685.


A fifteen-membered glycopeptide comprising glycyl, homoleucyl, alanyl, glycyl, cyclohexylalanyl, (5R)-5-(beta-D-galactopyranosyloxy)lysyl, glycyl. alpha-glutamyl, glutaminyl, glycyl, prolyl, lysyl, glycyl, alpha-glutamyl and threonine residues coupled in sequence.


name: RL40A_ARATH Ubiquitin-ribosomal protein eL40z fusion protein (sprot)

description: A ubiquitin-ribosomal protein eL40 fusion protein that is encoded in the genome of Arabidopsis thaliana.


A 1-acyl-sn-glycerol that has octadecanoyl (stearoyl) as the 1-acyl group.


A 1-monoglyceride that has stearoyl as the acyl group.


A 3-acyl-sn-glycerol that has octadecanoyl (stearoyl) as the 3-acyl group.


VISCUMNEOSIDE V

A viscumneoside that is viscumneoside III in which the primary hydroxy group of the beta-D-apiofuranosyl moiety has itself been converted to the corresponding beta-D-apiofuranoside derivative. Found in Viscum coloratum, an evergreen hemiparasitic plant whose stems and leaves are used in traditional Chinese medicine for the treatment of rheumatism.


adult papillary meningioma

category: biolink:Disease biolink:DiseaseOrPhenotypicFeature biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing

description: A papillary meningioma occurring in adults.


name: leucine zipper transcription factor-like protein 1 isoform 1 (human)

description: A leucine zipper transcription factor-like protein 1 isoform 1 that is encoded in the genome of human.


name: gamma-aminobutyric acid receptor subunit beta-1 isoform 1

description: A gamma-aminobutyric acid receptor subunit beta-1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P18505-1 or a 1:1 ortholog thereof.


name: gamma-aminobutyric acid receptor subunit beta-1

description: A GABA(A) receptor protein that is a translation product of the human GABRB1 gene or a 1:1 ortholog thereof.


name: gamma-aminobutyric acid receptor subunit beta-1 isoform 1 (mouse)

description: A gamma-aminobutyric acid receptor subunit beta-1 isoform 1 that is encoded in the genome of mouse.


name: GBRB1_MOUSE Gamma-aminobutyric acid receptor subunit beta-1 (sprot)

description: A gamma-aminobutyric acid receptor subunit beta-1 that is encoded in the genome of mouse.


name: gamma-aminobutyric acid receptor subunit beta-1, signal peptide removed form (human)

description: A gamma-aminobutyric acid receptor subunit beta-1 (human) that has had the signal peptide removed. UniProtKB:P18505, 26-474.


name: GBRB1_BOVIN Gamma-aminobutyric acid receptor subunit beta-1 (sprot)

description: A gamma-aminobutyric acid receptor subunit beta-1 that is encoded in the genome of cow.


name: gamma-aminobutyric acid receptor subunit beta-1 isoform 1 (rat)

description: A gamma-aminobutyric acid receptor subunit beta-1 isoform 1 that is encoded in the genome of rat.


name: gamma-aminobutyric acid receptor subunit beta-1 isoform h2 (human)

description: A gamma-aminobutyric acid receptor subunit beta-1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P18505-2.


name: G5ECN1_CAEEL Ligand-Gated ion Channel (trembl)

description: A gamma-aminobutyric acid receptor subunit beta-1 that is encoded in the genome of worm.


name: GBRB1_HUMAN Gamma-aminobutyric acid receptor subunit beta-1 (sprot)

description: A gamma-aminobutyric acid receptor subunit beta-1 that is encoded in the genome of human.


name: gamma-aminobutyric acid receptor subunit beta-1 isoform 1 (human)

description: A gamma-aminobutyric acid receptor subunit beta-1 isoform 1 that is encoded in the genome of human.


name: GBRB1_RAT Gamma-aminobutyric acid receptor subunit beta-1 (sprot)

description: A gamma-aminobutyric acid receptor subunit beta-1 that is encoded in the genome of rat.


name: YGEQ_ECOLI Uncharacterized lipoprotein YgeQ (sprot)

description: A protein that is a translation product of the ygeQ gene in Escherichia coli K-12.


name: RDL1_YEAST Thiosulfate:glutathione sulfurtransferase (sprot)

description: A thiosulfate:glutathione sulfurtransferase that is encoded in the genome of yeast.


A protein that is a translation product of the human TSTD1 gene or a 1:1 ortholog thereof.


name: thiosulfate:glutathione sulfurtransferase isoform h2 (human)

description: A thiosulfate:glutathione sulfurtransferase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8NFU3-2.


name: thiosulfate:glutathione sulfurtransferase isoform h1 (human)

description: A thiosulfate:glutathione sulfurtransferase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8NFU3-1.


name: thiosulfate:glutathione sulfurtransferase isoform h4 (human)

description: A thiosulfate:glutathione sulfurtransferase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8NFU3-4.


name: thiosulfate:glutathione sulfurtransferase isoform h3 (human)

description: A thiosulfate:glutathione sulfurtransferase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8NFU3-3.


name: RDL_SCHPO Putative thiosulfate sulfurtransferase, mitochondrial (sprot)

description: A thiosulfate:glutathione sulfurtransferase that is encoded in the genome of Schizosaccharomyces pombe 972h-.


name: TSTD1_HUMAN Thiosulfate:glutathione sulfurtransferase (sprot)

description: A thiosulfate:glutathione sulfurtransferase that is encoded in the genome of human.


First use syndrome

description: A symptom complex characterized by nervousness, chest pain, back pain, palpations, pruritus, and other usually mild symptoms occurring minutes following the initiation of dialysis with a new dialyzer.


name: OAT_YEAST Ornithine aminotransferase (sprot)

description: An ornithine aminotransferase, mitochondrial that is encoded in the genome of yeast.


name: uncharacterized HTH-type transcriptional regulator YdiP

description: A protein that is a translation product of the Escherichia coli K-12 ydiP gene or a 1:1 ortholog thereof.


name: YDIP_ECOLI Uncharacterized HTH-type transcriptional regulator YdiP (sprot)

description: An uncharacterized HTH-type transcriptional regulator YdiP that is encoded in the genome of Escherichia coli K-12.


cyclitol

A polyol consisting of a cycloalkane containing at least three hydroxy groups, each attached to a different ring carbon atom.


arbekacin

A kanamycin that is kanamycin B bearing an N-(2S)-4-amino-2-hydroxybutyryl group on the aminocyclitol ring.


conduritol epoxide

An epoxide resulting from the epoxidation of the double bond of a conduritol.


nebramycin 5'

A carbamoylkanamycin that is tobramycin bearing a single carbamoyl substituent located at position 6'' (on the 3-aminoglucose ring).


A myo-inositol pentakisphosphate that consists of 1D-myo-inositol having the five phospho groups located at positions 1, 2, 3, 4 and 5 as well as a diphospho group at position 6.


1D-myo-inositol 6-phosphate

A myo-inositol monophosphate in which the phosphate group is located at position 6.


A cyclitol that is valiolone in which the the stereochemistry at position 2 has been inverted (from R to S).


gamma-L-glutamylbutirosin B

A butirosin that is butirosin B in which a gamma-L-glutamyl is attached to the amino group of the (S)-4-amino-2-hydroxybutyrate side-chain.


VALIDOXYLAMINE A

An amino cyclitol that is (1R,2S,3S,4S,6R)-4-amino-6-(hydroxymethyl)cyclohexane-1,2,3-triol in which one of the hydrogens attached to the nitrogen is replaced by a (1R,4R,5R,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl group.


MANNOSTATIN A

An amino cyclitol that is cyclopentane substituted by hydroxy groups at positions 1, 2 and 3, by an amino group at positon 4, and by a methylsulfanediyl group at position 5 (the 1R,2R,3R,4S,5R-stereoisomer). It is isolated from the soil bacterium Streptoverticillium verticillium.


A myo-inositol tetrakisphosphate having the four phosphates placed in the 1-, 3-, 4- and 5-positions.


A member of the class of methyl myo-inositols that is cyclohexane-1,2,3,4,5-pentol substituted by a methoxy group at position 6 (the 1R,2S,3S,4S,5S,6S-isomer).


amino cyclitol

Any cyclitol having one or more alcoholic hydroxy groups replaced by substituted or unsubstituted amino groups.


kanamycin

Kanamycin is a naturally occurring antibiotic complex from Streptomyces kanamyceticus that consists of several components: kanamycin A, the major component (also usually designated as kanamycin), and kanamycins B, C, D and X the minor components.


inositol

Any cyclohexane-1,2,3,4,5,6-hexol.


6''-O-carbamoylkanamycin A

A carbamoylkanamycin that is kanamycin A bearing a single carbamoyl substituent located at position 6'' (on the 3-aminoglucose ring).


A 1D-myo-inositol pentakisphosphate compound with a diphosphate groups attached at the 4-position.


An amino cyclitol glycoside that is 4alpha,6alpha-diaminocyclohexane-1beta,2alpha,3beta-triol (2-deoxystreptamine) in which the pro-R hydroxy group is substituted by an alpha-D-glucosyl residue.


A 1D-myo-inositol tetrakisphosphate compound of unknown isomeric configuration with diphosphate groups attached at the two remainig vacant positions.


A 1D-myo-inositol bis(diphosphate) tetrakisphosphate having the two diphospho groups located at positions 1 and 3.


myo-inositol phosphate

An inositol phosphate in which the inositol component has myo-configuration.


lividomycin

Any member of a family of aminoglycosidic antibiotics produced by the bacterium Streptomyces lividus. Note that one member of this class, lividomycin A, is also known as lividomycin.


6'''-oxoneomycin C

An amino cyclitol glycoside derived from neomycin and consisting of neamine substituted at position 3 by a 3-O-(2-amino-2-deoxy-alpha-D-gluco-hexodialdo-1,5-pyranosyl)-beta-D-ribofuranosyl group.


5-epi-valiolone 7-phosphate

A member of the class of cyclitols that is 5-epi-valiolone carrying a phospho substituent at position 7.


An amino cyclitol glycoside that is 2-deoxystreptamine in which the pro-R hydroxy group is substituted by a 6-dehydro-alpha-D-glucosyl residue.


muco-inositol

An  inositol that is cyclohexane-1,2,3,4,5,6-hexol having a (1R,2R,3r,4R,5S,6r)-configuration.


A cyclitol phosphate that is 5a-carba-beta-D-mannose having a (4S,8S,12S,16S,20S)-4,8,12,16,20-pentamethylheptacosyl)phosphate group at position 1.


kanamycin X

A kanamycin that is kanamycin A in which the 6'-amino group is replaced by a hydroxy group.


valiolone

A cyclitol that is cyclohexanone which is substituted by hydroxy groups at positions 2, 3, 4, and 5, and by a hydroxymethyl group at position 5 (the 2R,3S,4S,5S stereoisomer).


A glycoside phosphate that is ribostamycin (vistamycin) in which the ribofuranosyl residue is substituted at position 5 by a phosphate group.


A 1D-myo-inositol bis(diphosphate) trisphosphate having the three phospho groups located at positions 1, 4 and 6 and the two diphospho groups at positions 3 and 5.


A member of the class of cyclitols that is valiolone in which the stererocentre at position 5 has been inverted.


A scyllo-inositol phosphate that is 1D-3-amino-1-guanidino-1,3-dideoxy-scyllo-inositol carrying a single phospho substituent at position 6.


A myo-inositol tetrakisphosphate having the four phosphate groups placed at the 3-, 4-, 5- and 6-positions.


A streptomycin bearing an additional hydroxy substituent at the 5'-position (on the furanose ring)


validone 7-phosphate

A cyclitol phosphate that is validone carrying a single monophosphate substituent at position 7.


streptidine 6-phosphate

A derivative of streptidine having a phosphate group at the 6-position.


A member of the class of cyclitols that is valiolone in which the stererocentres at positions 2 and 5 have been inverted.


3''-deamino-3''-hydroxykanamycin C

A kanamycin that is kanamycin C in which the 3''-amino group has been replaced by a hydroxy group.


A member of the class of methyl myo-inositols that is cyclohexane-1,2,3,4,5-pentol substituted by a methoxy group at position 6 (the 1R,2R,3S,4S,5R,6S-isomer).


dihydrostreptomycin 6-phosphate

The 6-O-phospho derivative of dihydrostreptomycin.


tobramycin

A amino cyclitol glycoside that is kanamycin B lacking the 3-hydroxy substituent from the 2,6-diaminoglucose ring.


Any myo-inositol trisphosphate bearing two additional diphospho substituents.


amikacin

An amino cyclitol glycoside that is kanamycin A acylated at the N-1 position by a 4-amino-2-hydroxybutyryl group.


A myo-inositol tetrakisphosphate that consists of myo-inositol having the four phospho groups located at positions 1, 4, 5 and 6 as well as a diphospho group at position 3.


A 1D-myo-inositol bis(diphosphate) tetrakisphosphate having the two diphospho groups located at positions 5 and 6.


seldomycin 5

An aminoglycoside antibiotic that is part of an antimicrobial complex consisting of factors 1,2,3,5 from a soil isolate named Streptomyces hofunensis.


astromicin

An amino cyclitol glycoside that is L-chiro-inositol in which the hydroxy groups at positions 1, 4, and 6 are replaced by aminoacetyl)methylamino, amino, and methoxy groups, respectively, and in which the hydroxy group at position 3 is converted to the corresponding 2,6-diamino-2,3,4,6,7-pentadeoxy-beta-L-lyxo-heptopyranoside. The major component of fortimicin, obtained from Micromonospora olivasterospora. It is administered (as the sulfate salt) by intramuscular injection or intravenous infusion for the treatment of severe systemic infections due to sensitive Gram-negative organisms.


2-deoxystreptamine derivative

Any derivative of 2-deoxystreptamine.


apramycin

An aminoglycoside that is 2-deoxystreptamine that is substituted on the oxygen at position 4 by an (8R)-2-amino-8-O-(4-amino-4-deoxy-alpha-D-glucopyranosyl)-2,3,7-trideoxy-7-(methylamino)-D-glycero-alpha-D-allo-octodialdo-1,5:8,4-dipyranos-1-yl) group.


validamine 7-phosphate

A cyclitol phosphate that is validamine carrying a single monophosphate substituent at position 7.


A scyllo-inositol phosphate having a monophosphate group at the 4-position as well as the hydroxy group at the 1-position replaced by an amino group.


mannostatin B

An amino cyclitol that is cyclopentane substituted by hydroxy groups at positions 1, 2 and 3, by an amino group at positon 4, and by a methylsulfinyl group at position 5 (the 1R,2R,3R,4S,5R-stereoisomer). It is isolated from the soil bacterium Streptoverticillium verticillium.


streptidine

An amino cyclitol that is scyllo-inositol in which the hydroxy groups at positions 1 and 3 are replaced by guanidino groups.


1D-myo-inositol 2-phosphate

A myo-inositol monophosphate in which the phosphate group is located at the 2-position.


dibekacin

A kanamycin that is kanamycin B lacking the 3- and 4-hydroxy groups on the 2,6-diaminosugar ring.


streptomycin

A amino cyclitol glycoside that consists of streptidine having a disaccharyl moiety attached at the 4-position. The parent of the streptomycin class


fortimicin KK1

An amino cyclitol glycoside that is (1R,2S,3S,4S,5S,6R)-2-amino-1,3,4,6-tetrahydroxy-5-(methylamino)cyclohexane in which the hydroxy group at position 1 is glycosylated by a heptapyranosyl residue.


GDP-valienol

A nucleotide conjugate consisting of CDP joined at the 1-position of valienol via a diphosphate linkage.


streptamine 5-phosphate

a scyllo-inositol phosphate compound having a phosphate group in the 5-position and amino groups in place of hydroxy groups in the 1- and 3-positions.


butirosin B

A butirosin that consists of neamine in which is substituted at position 2 by a beta-D-ribofuranosyl and at position 4 by an (S)-2-hydroxy-4-aminobutyryl group.


An amino cyclitol consisting of scyllo-inositol with the hydroxy groups at positions 1 and 3 replaced by unsubstituted amino groups and that at position 2 replaced by hydrogen.


etimicin

An aminoglycoside antibiotic that is gentamycin C1a in which the hydrogen of the amino group at position 1 is substituted by an ethyl group. It is a fourth generation semisynthetic aminoglycoside that has antimicrobial activity against both gram-positive and gram-negative bacterial infections and also effective against aminoglycoside resistant strains.


3''-deamino-3''-hydroxykanamycin B

A kanamycin that is kanamycin B in which the 3''-amino group has been replaced by a hydroxy group.


D-chiro-inositol

Belonging to the inositol family of compounds, D-chiro-inositol (DCI) is an isomer of glucose. It is an important secondary messenger in insulin signal transduction.


BUTIROSIN A

A butirosin that consists of neamine in which is substituted at position 2 by a beta-D-xylofuranosyl and at position 4 by an (S)-2-hydroxy-4-aminobutyryl group.


valienol 1-phosphate

A cyclitol phosphate that is valienol carrying a sigle monophosphate group at position 1.


gentamicin

Any of a group of aminoglycoside antibiotics produced by fermentation of some Micromonospora spp.


A 1D-myo-inositol bis(diphosphate) tetrakisphosphate having the two diphospho groups located at positions 1 and 4.


bacteriohopanetetrol cyclitol ether

A hopanoid that is isolated from Burkholderia cenocepacia and Methylobacterium organophilum.


Any member of the class of  streptomycins that is dihydrostreptomycin in which the hydroxy group at position 3' is replaced by a hydrogen.


A member of the class of methyl myo-inositols that is cyclohexane-1,2,3,4,5-pentol substituted by a methoxy group at position 6 ( the 1R,2R,3R,4R,5S,6R-isomer).


A scyllo-inositol phosphate compound having the phosphate group at the 6-position, guanidino groups replacing hydroxy functions at the 1-position and an alpha-L-lyxofuranosyl residue at the 4-position.


A scyllo-inositol phosphate having the phosphate at the 4-position and a guanidino group in place of the hydroxyl at position 1.


A member of the class of methyl myo-inositols that is cyclohexane-1,2,3,4,5-pentol substituted by a methoxy group at position 6 (the 1R,2S,3r,4R,5S,6r-stereoisomer).


A myo-inositol pentakisphosphate that consists of myo-inositol having the five phospho groups located at positions 1, 2, 4, 5 and 6 as well as a diphospho group at position 3.


validamine

An amino cyclitol consisting of 1D-chiro-inositol lacking the 6-hydroxy group and having those at positions 1 and 5 replaced by amino and hydroxymethyl groups respectively.


butirosin

A family of amino cyclitol glycoside antibiotics produced by Bacillus circulans, bears the unique (S)-4-amino-2-hydroxybutyrate (AHBA) side chain.


(+)-conduritol B

A conduritol which has 1S,2R,3R,4S configuration.


CONDURITOL B EPOXIDE

A conduritol epoxide resulting from the formal epoxidation of the double bond of (+)-conduritol B.


diphosphoinositol polyphosphate

An inositol phosphate that is inositol substituted by one or more diphosphate groups and with multiple monophosphate groups attached.


An amino cyclitol that is scyllo-inosamine in which the 2-hydroxy group is substituted by hydrogen.


conduritol

A tetrol that is cyclohexene in which a hydrogen attached to each of the carbons at positions 3, 4, 5, and 6 is replaced by a hydroxy group. The group consists of six possible diastereoisomers, known as conduritols A to F, some of which can exist as two distinct enantiomers.


streptomycin 3''-phosphate

A streptomycin phosphate having the phosphate group placed at the 3''-position.


kanamycin D

A kanamycin that is kanamycin A in which the 3''-amino group is replaced by a hydroxy group.


myo-inositol monophosphate

A myo-inositol phosphate that is myo-inositol in which one of the hydroxy groups is replaced by a phosphate group. A 'closed class'.


A 1D-myo-inositol bis(diphosphate) tetrakisphosphate having the two diphospho groups located at positions 4 and 5.


1D-myo-inositol 5-phosphate

An inositol having myo- configuration substituted at position 5 by a phosphate group.


lividomycin B

A member of the class of lividomycins that is paromomycin in which the 2-amino-2-deoxyglucopyranosyl moiety is lacking the hydroxy group at position 3.


(-)-conduritol B

A conduritol which has 1R,2S,3S,4R configuration.


A myo-inositol bis(diphosphate) trisphosphate having the three phospho groups located at positions 4, 5 and 6 and the two diphospho groups at positions 1 and 3.


N(6')-acetylkanamycin B

An N(6')-acetylkanamycin derived from kanamycin B.


A kanamycin obtained by dehydrogenation at position 2' of kanamycin A.


validone

A member of the class of hydroxycyclohexanones that is cyclohexanone substituted by hydroxy groups at positions 2, 3 and 4, and by a hydroxymethyl group at position 5 (the 2R,3S,4R,5R-diastereomer).


A myo-inositol pentakisphosphate that consists of myo-inositol having the five phospho groups located at positions 2, 3, 4, 5 and 6 as well as a diphospho group at position 1.


validoxylamine B

An amino cyclitol that is (1S,2S,3R,6S)-6-amino-4-(hydroxymethyl)cyclohex-4-ene-1,2,3-triol in which one of the hydrogens attached to the nitrogen is replaced by a (1R,2S,3R,4R,5S,6S)-2,3,4,6-tetrahydroxy-5-(hydroxymethyl)cyclohexyl group.


3''-deamino-3''-hydroxykanamycin X

A kanamycin that is kanamycin X in which the 3''-amino group has been replaced by a hydroxy group.


An inositol phosphate consisting of two units of 1L-myo-inositol phosphate in which the phosphate group of the first is joined to the 3-position of the second.


carbamoylkanamycin

Any kanamycin carrying one or more carbamoyl substituents


A conduritol epoxide resulting from the formal epoxidation of the double bond of (-)-conduritol B.


An amino cyclitol glycoside that is 2-deoxystreptamine in which the pro-R hydroxy group is substituted by a 6-amino-6-deoxy-alpha-D-glucosyl residue.


An oligosaccharide phosphate consisting of D-myo-inositol having a 6-O-(2-aminoethylphosphono)-alpha-D-mannosyl-(1->2)-alpha-D-mannosyl-(1->6)-alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl residue attached at the 6-position.


1D-myo-inositol 2,4-bisphosphate

A myo-inositol bisphosphate in which the two phosphate groups are located at positions 2 and 4.


neomycin

A broad-spectrum highly toxic antibiotic or mixture of antibiotics produced by a streptomyces (Streptomyces fradiae) and used medically especially to treat local infections.


ribostamycin

An amino cyclitol glycoside that is 4,6-diaminocyclohexane-1,2,3-triol having a 2,6-diamino-2,6-dideoxy-alpha-D-glucosyl residue attached at position 1 and a beta-D-ribosyl residue attached at position 2. It is an antibiotic produced by Streptomyces ribosidificus (formerly S. thermoflavus).


2-epi-5-epi-valiolone 7-phosphate

A member of the class of cyclitols that is 2-epi-5-epi-valiolone carrying a phospho substituent at position 7.


A myo-inositol tetrakisphosphate having the four phosphates placed in the 1-, 2-, 5- and 6-positions.


streptamine

An amino cyclitol consisting of scyllo-inositol with the hydroxy groups at positions 1 and 3 replaced by unsubstituted amino groups.


An amino cyclitol that is streptidine in which the hydroxy group between the two guanidino groups is replaced by hydrogen.


A 1D-myo-inositol bis(diphosphate) tetrakisphosphate having the two diphospho groups located at positions 1 and 5.


KASUGAMYCIN

An amino cyclitol glycoside that is isolated from Streptomyces kasugaensis and exhibits antibiotic and fungicidal properties.


A 1D-myo-inositol bis(diphosphate) tetrakisphosphate having the two diphospho groups located at positions 3 and 5.


1D-myo-inositol 3,5-bisphosphate

A myo-inositol bisphosphate in which the two phosphate groups are located at positions 3 and 5


conduritol A

A conduritol in which the hydroxy groups at positions 2, 3, and 4 are in a trans,trans,cis- relationship to that at position 1.


An N-acyl-1-deoxy-4-hydroxysphinganine in which the acyl group on nitrogen is hexacosanoyl and in which C-1 is substituted by a cyclitolic [(1S,2S,3R,4R,5S)-2,3,4,5-tetrahydroxycyclohexyl] amino group. It is a synthetic analogue of the CD1d-presented agonist alpha-galactosylceramide.


paromomycin

An amino cyclitol glycoside that is the 1-O-(2-amino-2-deoxy-alpha-D-glucopyranoside) and the 3-O-(2,6-diamino-2,6-dideoxy-beta-L-idopyranosyl)-beta-D-ribofuranoside of 4,6-diamino-2,3-dihydroxycyclohexane (the 1R,2R,3S,4R,6S diastereoisomer). It is obtained from various Streptomyces species. A broad-spectrum antibiotic, it is used (generally as the sulfate salt) for the treatment of acute and chronic intestinal protozoal infections, but is not effective for extraintestinal protozoal infections. It is also used as a therapeutic against visceral leishmaniasis.


A member of the class of methyl myo-inositols that is cyclohexane-1,2,3,4,5-pentol substituted by a methoxy group at position 6 (the 1S,2R,3R,4S,5S,6R-isomer).


methyl myo-inositols

A cyclitol that is myo-inositol in which one of the alcoholic hydrogens is substituted by a methyl group.


validoxylamine A 7'-phosphate

A cyclitol phosphate that is validoxylamine A carrying a single monophosphate substituent at position 7'.


myo-inositol 1,3,4,6-tetrakisphosphate

A myo-inositol tetrakisphosphate having the phosphate groups placed at the 1-, 3-, 4- and 6-positions.


name: B Acute Lymphoblastic Leukemia with Intrachromosomal Amplification of Chromosome 21

description: B-acute lymphoblastic leukemia characterized by amplification of a portion of chromosome 21. It usually occurs in children and is associated with an adverse prognosis.


RIPL1_MOUSE RILP-like protein 1 (sprot)

A RILP-like protein 1 that is encoded in the genome of mouse.


RILP-like protein 1

A protein that is a translation product of the human RILPL1 gene or a 1:1 ortholog thereof.


RILP-like protein 1 isoform h3 (human)

A RILP-like protein 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q5EBL4-3.


RILP-like protein 1 isoform h1 (human)

A RILP-like protein 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q5EBL4-1.


RIPL1_RAT RILP-like protein 1 (sprot)

A RILP-like protein 1 that is encoded in the genome of rat.


RIPL1_HUMAN RILP-like protein 1 (sprot)

A RILP-like protein 1 that is encoded in the genome of human.


RILP-like protein 1 isoform h2 (human)

A RILP-like protein 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q5EBL4-2.


name: RIPL_DROME RILP-like protein homolog (sprot)

description: A RILP-like protein 1 that is encoded in the genome of fruit fly.


RILP-like protein 1 isoform 1 (rat)

A RILP-like protein 1 isoform 1 that is encoded in the genome of rat.


RILP-like protein 1 isoform 1

A RILP-like protein 1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9JJC6-1 or a 1:1 ortholog thereof.


RILP-like protein 1 isoform 1 (mouse)

A RILP-like protein 1 isoform 1 that is encoded in the genome of mouse.


name: partner and localizer of BRCA2 sequence variant E1002* (human)

description: A partner and localizer of BRCA2 (human) that has has been truncated after the position equivalent to Lys-1001 of the amino acid sequence represented by UniProtKB:Q86YC2. UniProtKB:Q86YC2, 1-1001.


name: fusion of virus membrane with host macropinosome membrane

description: Fusion of a viral membrane with a host macropinosome membrane, that occurs after internalization of the virus through the endosomal pathway, and results in release of the viral contents into the host cell cytoplasm.


name: exocyst complex component 5 isoform 1 (mouse)

description: An exocyst complex component 5 isoform 1 that is encoded in the genome of mouse.


name: homeobox protein unc-62 isoform f (worm)

description: A homeobox protein unc-62 (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9N5D6-6.


4-chloro-L-lysine zwitterion

An L-alpha-amino acid zwitterion obtained by transfer of a proton from the carboxy to the amino group of 4-chloro-L-lysine


name: F-box protein At1g66490 isoform 2 (Arabidopsis thaliana)

description: An F-box protein At1g66490 (Arabidopsis thaliana) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q1PFG1-2.


name: FB74_ARATH F-box protein At1g66490 (sprot)

description: A protein that is a translation product of the At1g66490 gene in Arabidopsis thaliana.


name: F-box protein At1g66490 isoform 1 (Arabidopsis thaliana)

description: An F-box protein At1g66490 (Arabidopsis thaliana) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q1PFG1-1.


Matthew-Wood syndrome

description: Matthew-Wood syndrome is a rare clinical entity including as main characteristics anophthalmia or severe microphthalmia, and pulmonary hypoplasia or aplasia.


description: Catalysis of the reaction: tetradecanoyl-CoA + glycyl-peptide = CoA + N-tetradecanoylglycyl-peptide.


name: U74D1_ARATH UDP-glycosyltransferase 74D1 (sprot)

description: A protein that is a translation product of the UGT74D1 gene in Arabidopsis thaliana.


name: Testicular Mixed Germ Cell-Sex Cord-Stromal Tumor

description: A testicular mixed germ cell-sex cord-stromal tumor in which the neoplastic germ cells and the neoplastic sex cord-stromal cells do not form nests and are instead arranged in a diffuse pattern.


Sesterviridene B

A sesterterpene that is produced by a sesterterpene synthase from Kitasatospora viridis.


Empyema with fistula

description: An empyema with a fistula.


name: UPF0739 protein C1orf74 methylated 1 (human)

description: A UPF0739 protein C1orf74 (human) that has been methylated on the residue at the position equivalent to Cys-36 of the amino acid sequence represented by UniProtKB:Q96LT6. UniProtKB:Q96LT6, Cys-36, MOD:00660.


protein NDRG3 phosphorylated 1 (human)

A protein NDRG3 (human) that has been phosphorylated on the residue at the position equivalent to Thr-183 of the amino acid sequence represented by UniProtKB:Q9UGV2-1. Example: UniProtKB:Q9UGV2-1, Thr-183, MOD:00047.


protein NDRG3

A protein that is a translation product of the human NDRG3 gene or a 1:1 ortholog thereof.


protein NDRG3 deaminated 3 (human)

A protein NDRG3 (human) that has been deaminated on the residue at the position equivalent to Asn-202 of the amino acid sequence represented by UniProtKB:Q9UGV2-1. Example: UniProtKB:Q9UGV2-1, Asn-202, MOD:00684.


protein NDRG3 methylated 1 (human)

A protein NDRG3 (human) that has been methylated on the residue at the position equivalent to Cys-166 of the amino acid sequence represented by UniProtKB:Q9UGV2-1. Example: UniProtKB:Q9UGV2-1, Cys-166, MOD:00660.


protein NDRG3 deaminated 1 (human)

A protein NDRG3 (human) that has been deaminated on the residue at the position equivalent to Asn-184 of the amino acid sequence represented by UniProtKB:Q9UGV2-1. Example: UniProtKB:Q9UGV2-1, Asn-184, MOD:00684.


protein NDRG3 isoform 1 (mouse)

A protein NDRG3 isoform 1 that is encoded in the genome of mouse.


protein NDRG3 isoform h2 (human)

A protein NDRG3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9UGV2-2.


protein NDRG3 deaminated 2 (human)

A protein NDRG3 (human) that has been deaminated on the residue at the position equivalent to Gln-196 of the amino acid sequence represented by UniProtKB:Q9UGV2-1. Example: UniProtKB:Q9UGV2-1, Gln-196, MOD:00685.


protein NDRG3 isoform 1

A protein NDRG3 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9UGV2-1 or a 1:1 ortholog thereof.


protein NDRG3 isoform 1 (human)

A protein NDRG3 isoform 1 that is encoded in the genome of human.


NDRG3_HUMAN Protein NDRG3 (sprot)

A protein NDRG3 that is encoded in the genome of human.


NDRG_DICDI NDRG-like protein (sprot)

A protein NDRG3 that is encoded in the genome of Dictyostelium discoideum.


NDRG3_MOUSE Protein NDRG3 (sprot)

A protein NDRG3 that is encoded in the genome of mouse.


protein NDRG3 isoform h3 (human)

A protein NDRG3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9UGV2-3.


NDRG3_RAT Protein NDRG3 (sprot)

A protein NDRG3 that is encoded in the genome of rat.


protein NDRG3 cysteinylated 1 (human)

A protein NDRG3 (human) that has been cysteinylated on the residue at the position equivalent to Cys-254 of the amino acid sequence represented by UniProtKB:Q9UGV2-1. Example: UniProtKB:Q9UGV2-1, Cys-254, MOD:00765.


U522B_DICDI UPF0522 protein B (sprot)

A protein that is a translation product of the bpiB gene in Dictyostelium discoideum.


name: vesicle transport through interaction with t-SNAREs homolog 1B isoform 1

description: A vesicle transport through interaction with t-SNAREs homolog 1B that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9UEU0-1 or a 1:1 ortholog thereof.


name: vesicle transport through interaction with t-SNAREs homolog 1B isoform Long (human)

description: A vesicle transport through interaction with t-SNAREs homolog 1B isoform 1 that is encoded in the genome of human.


name: vesicle transport through interaction with t-SNAREs homolog 1B isoform 1 (rat)

description: A vesicle transport through interaction with t-SNAREs homolog 1B isoform 1 that is encoded in the genome of rat.


name: ribosomal protein eS27-like isoform 1 (rat)

description: A ribosomal protein eS27-like protein isoform 1 that is encoded in the genome of rat.


protein PRRC2C isoform h7 (human)

A protein PRRC2C (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9Y520-7.


name: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 isoform 1 (mouse)

description: An NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 isoform 1 that is encoded in the genome of mouse.


name: large ribosomal subunit protein P2z isoform 1 (Arabidopsis thaliana)

description: A large ribosomal subunit protein P2z (Arabidopsis thaliana) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P51407-1.


name: RLA21_ARATH Large ribosomal subunit protein P2z (sprot)

description: A large ribosomal subunit protein P2 that is encoded in the genome of Arabidopsis thaliana.


name: basic leucine zipper 10 isoform 2 (Arabidopsis thaliana)

description: A basic leucine zipper 10 (Arabidopsis thaliana) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O22763-2.


name: PTA1_YEAST Pre-tRNA-processing protein PTA1 (sprot)

description: A protein that is a translation product of the PTA1 gene in yeast.


BENZO[D]ISOXAZOLE

A benzoxazole in which the benzene ring is fused to a 1,2-oxazole ring across positions 4 and 5.


name: acyl-coenzyme A thioesterase MBLAC2 isoform 1

description: An acyl-coenzyme A thioesterase MBLAC2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q68D91-1 or a 1:1 ortholog thereof.


name: acyl-coenzyme A thioesterase MBLAC2 isoform 1 (mouse)

description: An acyl-coenzyme A thioesterase MBLAC2 isoform 1 that is encoded in the genome of mouse.


name: actin nucleation-promoting factor WAS, initiator methionine removed phosphorylated 1 (human)

description: An actin nucleation-promoting factor WAS (human) that has had the initiator methionine removed and that has been phosphorylated on the residue at the position equivalent to Tyr-291 of the amino acid sequence represented by UniProtKB:P42768. UniProtKB:P42768, 2-502, Tyr-291, MOD:00048.


cysteinyl leukotriene receptor

A leukotriene receptor that in active form binds cysteinyl leukotriene.


cysteinyl leukotriene receptor 1

A cysteinyl leukotriene receptor that is a translation product of the human CYSLTR1 gene or a 1:1 ortholog thereof. The preferred ligand is the cysteinyl leukotriene D4.


name: CLTR1_CAVPO Cysteinyl leukotriene receptor 1 (sprot)

description: A cysteinyl leukotriene receptor 1 that is encoded in the genome of guinea pig.


name: cysteinyl leukotriene receptor 2 isoform 1 (rat)

description: A cysteinyl leukotriene receptor 2 isoform 1 that is encoded in the genome of rat.


name: cysteinyl leukotriene receptor 1 isoform m1 (mouse)

description: A cysteinyl leukotriene receptor 1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q99JA4-1.


name: cysteinyl leukotriene receptor 1 methylated 1 (human)

description: A cysteinyl leukotriene receptor 1 (human) that has been methylated on the residue at the position equivalent to Cys-289 of the amino acid sequence represented by UniProtKB:Q9Y271. UniProtKB:Q9Y271, Cys-289, MOD:00660.


name: cysteinyl leukotriene receptor 1 isoform 1 (rat)

description: A cysteinyl leukotriene receptor 1 isoform 2 that is encoded in the genome of rat.


name: cysteinyl leukotriene receptor 1 isoform 2

description: A cysteinyl leukotriene receptor 1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q99JA4-2 or a 1:1 ortholog thereof.


name: cysteinyl leukotriene receptor 2 isoform 1

description: A cysteinyl leukotriene receptor 2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q920A1-1 or a 1:1 ortholog thereof.


name: cysteinyl leukotriene receptor 2 isoform 1 (mouse)

description: A cysteinyl leukotriene receptor 2 isoform 1 that is encoded in the genome of mouse.


cysteinyl leukotriene receptor 2

A cysteinyl leukotriene receptor that is a translation product of the human CYSLTR2 gene or a 1:1 ortholog thereof. The preferred ligand is the cysteinyl leukotriene C4.


name: pleckstrin homology domain-containing family A member 7 phosphorylated 1 (human)

description: A pleckstrin homology domain-containing family A member 7 (human) that has been phosphorylated on the residue at the position equivalent to Thr-477 of the amino acid sequence represented by UniProtKB:Q6IQ23-1. Example: UniProtKB:Q6IQ23-1, Thr-477, MOD:00047.


positive regulation of CD4 production

description: Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of CD4.


regulation of CD4 production

description: Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of CD4.


negative regulation of CD4 production

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of CD4.


name: Luc7-like protein 3 methylated 1 (human)

description: A Luc7-like protein 3 (human) that has been methylated on the residue at the position equivalent to Cys-35 of the amino acid sequence represented by UniProtKB:O95232-1. Example: UniProtKB:O95232-1, Cys-35, MOD:00660.


A pseudoguaianolide with anti-inflammatory activity isolated from the aerial parts of Inula hupehensis


name: Ras-related protein Rab-40C isoform 1 (mouse)

description: A Ras-related protein Rab-40C isoform 1 that is encoded in the genome of mouse.


name: RB40C_MOUSE Ras-related protein Rab-40C (sprot)

description: A Ras-related protein Rab-40C that is encoded in the genome of mouse.


name: DNA-binding protein SATB2 isoform 1 (mouse)

description: A DNA-binding protein SATB2 isoform 1 that is encoded in the genome of mouse.


name: DNA-binding protein SATB2 isoform m2 (mouse)

description: A DNA-binding protein SATB2 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8VI24-2.


protein ANKUB1 isoform h3 (human)

A protein ANKUB1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:A6NFN9-3.


name: proliferation-associated protein 2G4, initiator methionine removed form (human)

description: A proliferation-associated protein 2G4 (human) that has had the initiator methionine removed. Example: UniProtKB:Q9UQ80-1, 2-394.


name: EDL16_ARATH Sugar transporter ERD6-like 16 (sprot)

description: A protein that is a translation product of the At5g18840 gene in Arabidopsis thaliana.


name: CWC27_YEAST Peptidyl-prolyl isomerase CWC27 (sprot)

description: A protein that is a translation product of the CWC27 gene in yeast.


name: RNA-binding protein 1 isoform D (fruit fly)

description: An RNA-binding protein 1 (fruit fly) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q02427-3.


name: carbon catabolite repression of transcription from RNA polymerase II promoter by glucose

description: A transcription regulation process in which the presence of glucose leads to a decrease in the frequency, rate, or extent of transcription of specific RNA polymerase II-transcribed genes involved in the metabolism of other carbon sources. Carbon catabolite repression is a mechanism of genetic regulation which the accumulation of catabolites of one substance in the cell represses the formation of enzymes that contribute to the catabolism of other substances.


name: negative regulation of transcription by glucose

description: Any process involving glucose that decreases the frequency, rate or extent or transcription.


name: carbon catabolite repression of transcription by glucose

description: A transcription regulation process in which the presence of glucose leads to a decrease in the frequency, rate, or extent of transcription of specific genes involved in the metabolism of other carbon sources. Carbon catabolite repression is a mechanism of genetic regulation which the accumulation of catabolites of one substance in the cell represses the formation of enzymes that contribute to the catabolism of other substances.


name: negative regulation of transcription from RNA polymerase II promoter by glucose

description: Any process involving glucose that decreases the frequency, rate or extent or transcription from an RNA polymerase II promoter.


name: endoplasmic reticulum aminopeptidase 2 isoform h3 (human)

description: An endoplasmic reticulum aminopeptidase 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q6P179-3.


name: TRPC_ECOLI Tryptophan biosynthesis protein TrpCF (sprot)

description: A tryptophan biosynthesis protein TrpCF that is encoded in the genome of Escherichia coli K-12.


name: C-Jun-amino-terminal kinase-interacting protein 4 isoform h6 (human)

description: A C-Jun-amino-terminal kinase-interacting protein 4 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O60271-9.


name: SGS4_DROME Salivary glue protein Sgs-4 (sprot)

description: A protein that is a translation product of the Sgs4 gene in fruit fly.


vasomotor rhinitis

description: Inflammation in the nasal cavity mucosa that results from the abnormal regulation of the blood flow in the nose. It may be caused by temperature fluctuations, air pollution, strong odors, and tobacco smoke. It results in chronic nasal congestion, sneezing, and running nose.


common cold

description: An inflammatory process affecting the nasal mucosa, usually caused by viruses (e.g., rhinovirus, adenovirus, parainfluenza virus, and coronavirus). It is characterized by chills, headaches, mucopurulent nasal discharge, coughing, and facial pain.


perennial allergic rhinitis

description: Allergic rhinitis caused by indoor allergens and lasting year round.


beta-chimaerin isoform h7 (human)

A beta-chimaerin (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P52757-7.


name: PABP7_ARATH Polyadenylate-binding protein 7 (sprot)

description: A polyadenylate-binding protein 1-like that is encoded in the genome of Arabidopsis thaliana.


olfactory receptor 10H28

A protein that is a translation product of the mouse Olfr63 gene or a 1:1 ortholog thereof.


name: 10H28_MOUSE Olfactory receptor 10H28 (sprot)

description: An olfactory receptor 10H28 that is encoded in the genome of mouse.


name: CYSP1_DICDI Cysteine proteinase 1 (sprot)

description: A protein that is a translation product of the cprA gene in Dictyostelium discoideum.


name: congenital plasminogen activator inhibitor type 1 deficiency

description: Congenital plasminogen activator inhibitor type 1 (PAI-1) deficiency is a rare genetic bleeding disorder characterized by premature lysis of hemostatic clots and a moderate bleeding tendency.


olfactory receptor 1S1

A class II olfactory receptor that is a translation product of the human OR1S1 gene or a 1:1 ortholog thereof.


name: OR1S1_HUMAN Olfactory receptor 1S1 (sprot)

description: An olfactory receptor 1S1 that is encoded in the genome of human.


name: DEVR_MYCTU DNA-binding transcriptional activator DevR/DosR (sprot)

description: A protein that is a translation product of the devR gene in Mycobacterium tuberculosis H37Rv.


ROTIORINOL C

An azaphilone that is 9,9a-dihydro-2H-furo[3,2-g]isochromen-2-one substituted by an acetyl group at position 3, a hydroxy group at position 9, a 7-hydroxy-3,5-dimethylhepta-1,3-dien-1-yl group at position 6 and a methyl group at position 9a. It has been isolated from Chaetomium cupreum and exhibits antifungal activity.


name: Advanced Chromophobe Renal Cell Carcinoma

description: Chromophobe renal cell carcinoma that has spread extensively to other anatomic sites or is no longer responding to treatment.


Advanced Adenocarcinoma

description: An adenocarcinoma that has spread extensively to other anatomic sites or is no longer responding to treatment.


name: Advanced Progesterone Receptor-Positive Breast Carcinoma

description: Progesterone receptor-positive breast carcinoma that has spread extensively to other anatomic sites or is no longer responding to treatment.


name: Advanced Ovarian Clear Cell Adenocarcinoma

description: Ovarian clear cell adenocarcinoma that has spread extensively to other anatomic sites or is no longer responding to treatment.


name: Advanced Endometrial Endometrioid Adenocarcinoma

description: Endometrial endometrioid adenocarcinoma that has spread extensively to other anatomic sites or is no longer responding to treatment.


description: Intrahepatic cholangiocarcinoma that has spread extensively to other anatomic sites or is no longer responding to treatment.


Advanced Sebaceous Carcinoma

description: Sebaceous carcinoma that has spread extensively to other anatomic sites or is no longer responding to treatment.


name: Advanced Distal Bile Duct Adenocarcinoma

description: Distal bile duct adenocarcinoma that has spread extensively to other anatomic sites or is no longer responding to treatment.


Advanced renal cell carcinoma

description: Renal cell carcinoma that has spread extensively to other anatomic sites or is no longer responding to treatment.


name: Advanced Prostate Adenocarcinoma with Neuroendocrine Differentiation

description: Prostate adenocarcinoma with neuroendocrine differentiation that has spread extensively to other anatomic sites or is no longer responding to treatment.


Advanced Gastric Adenocarcinoma

description: Gastric adenocarcinoma that has spread extensively to other anatomic sites or is no longer responding to treatment.