name: planar cell polarity pathway involved in pericardium morphogenesis

description: The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity that contributes to the shaping of the pericardium.


name: regulation of dopamine biosynthetic process

category: biolink:BiologicalProcess biolink:Occurrent biolink:OntologyClass biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: Any process that modulates the frequency, rate or extent of dopamine biosynthetic process.


name: histone H3K9 trimethyltransferase activity

category: biolink:MolecularActivity biolink:Occurrent biolink:OntologyClass biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: Catalysis of the reaction: L-lysyl9-[histone H3] + 3 S-adenosyl-L-methionine = 3 H+ + N6,N6,N6-trimethyl-L-lysyl9-[histone H3] + 3 S-adenosyl-L-homocysteine. This reaction is the successive addition of three methyl groups to the unmethylated lysine residue at position 9 of histone H3, producing histone H3K9me3.


name: apoptotic process involved in embryonic digit morphogenesis

description: Any apoptotic process that is involved in embryonic digit morphogenesis.


name: regulation of tetrapyrrole metabolic process

description: Any process that modulates the frequency, rate or extent of tetrapyrrole metabolic process.


name: response to pheromone triggering conjugation with cellular fusion

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pheromone stimulus that positively regulates the process of conjugation with cellular fusion. An example of this process is found in Saccharomyces cerevisiae.


dioxygenase activity

description: Catalysis of an oxidation-reduction (redox) reaction in which both atoms of oxygen from one molecule of O2 are incorporated into the (reduced) product(s) of the reaction. The two atoms of oxygen may be distributed between two different products.


name: wobble position cytosine ribose methylation

description: The process in which the ribose of cytidine at position 34 in the anticodon of a tRNA is post-transcriptionally methylated at the 2'-O position.


name: terpenoid indole alkaloid metabolic process

description: The chemical reactions and pathways involving terpenoid indole alkaloids, compounds formed from the condensation of tryptamine (derived from tryptophan) and secologanin (derived from geranyl pyrophosphate).


description: The acetylation of the N-terminal cysteine of proteins to form the derivative N-acetyl-L-cysteine.


peptidyl-tryptophan succinylation

description: The modification of an N-terminal peptidyl-tryptophan residue to form peptidyl-N2-succinyl-L-tryptophan.


poly-purine tract binding

description: Binding to a stretch of purines (adenine or guanine) in an RNA molecule.


name: cellular response to oxygen-containing compound

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxygen-containing compound stimulus.


description: Catalysis of the reaction: adenosine57/adenosine58 in tRNA + 2 S-adenosyl-L-methionine = 2 H+ + N1-methyladenosine57/N1-methyladenosine58 in tRNA + 2 S-adenosyl-L-homocysteine.


name: nucleoside diphosphate catabolic process

description: The chemical reactions and pathways resulting in the breakdown of a nucleoside diphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with diphosphate on the sugar.


response to iron(II) ion

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron(II) ion stimulus.


name: positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway

description: Any process that activates or increases the frequency, rate or extent of phospholipase C-activating G protein-coupled receptor signaling pathway.


D-xylose metabolic process

description: The chemical reactions and pathways involving D-xylose, a naturally occurring plant polysaccharide.


name: G protein-coupled receptor catabolic process

description: The chemical reactions and pathways resulting in the breakdown of a G protein-coupled receptor.


description: Catalysis of the reaction: 13-hydroxydocosanoate + UDP-D-glucose = 13-beta-D-glucosyloxydocosanoate + UDP.


name: adhesion of symbiont haustorium mother cell to host

description: The attachment of a haustorium mother cell of the symbiont to its host via adhesion molecules. The host is defined as the larger of the organisms involved in a symbiotic interaction.


name: 16-alpha-hydroxysteroid dehydrogenase (NADP+) activity

description: Catalysis of the reaction: NADP+ + 16-alpha-hydroxysteroid = NADPH + H+ + 16-oxosteroid.


RNA 5'-cap (guanine-N7)-methylation

description: The process whereby a guanine in 5-cap is methylated at the N7 position of guanine.


arabinan catabolic process

description: The chemical reactions and pathways resulting in the breakdown of arabinan, a polysaccharide composed of arabinose residues.


name: negative regulation of brown fat cell differentiation

description: Any process that stops, prevents or reduces the frequency, rate or extent of brown fat cell differentiation.


andrastin A biosynthetic process

description: The chemical reactions and pathways resulting in the formation of andrastin A, a meroterpenoid that exhibits inhibitory activity against ras farnesyltransferase, suggesting that it could have promising antitumor activity.


Rho protein signal transduction

category: biolink:Pathway biolink:OntologyClass biolink:BiologicalProcess biolink:Occurrent biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: An intracellular signaling cassette in which a small monomeric GTPase of the Rho subfamily relays a signal.


name: double-strand break repair via single-strand annealing

description: Repair of a DSB made between two repeated sequences oriented in the same direction occurs primarily by the single strand annealing pathway. The ends of the break are processed by a 5' to 3' exonuclease, exposing complementary single-strand regions of the direct repeats that can anneal, resulting in a deletion of the unique DNA between the direct repeats.


name: galactosyl beta-1,3 N-acetylgalactosamine beta-1,3-glucuronosyltransferase activity

description: Catalysis of the transfer, in a beta 1,3 linkage, of D-glucuronic acid (GlcUA) from UDP-GlcUA to the disaccharide galactosyl beta-1,3 N-acetylgalactosamine, a common component of glycoproteins and glycolipids.


name: IRES-dependent viral translational initiation

description: Process by which viral mRNA translation is initiated, where a domain in the 5' untranslated region (UTR) of the viral mRNA called an internal ribosome entry site (IRES) binds the host 43S preinitiation complex, circumventing regular cap-dependent translation initiation.


anaerobic fatty acid catabolic process

description: The chemical reactions and pathways resulting in the breakdown of a fatty acid in the absence of oxygen. A fatty acid is any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils. Fatty acids are predominantly straight-chain acids of 4 to 24 carbon atoms, which may be saturated or unsaturated; branched fatty acids and hydroxy fatty acids also occur, and very long chain acids of over 30 carbons are found in waxes.


phosphatidylinositol catabolic process

description: The chemical reactions and pathways resulting in the breakdown of phosphatidylinositol, any glycophospholipid with its sn-glycerol 3-phosphate residue is esterified to the 1-hydroxyl group of 1D-myo-inositol.


dopamine biosynthetic process

description: The chemical reactions and pathways resulting in the formation of dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline.


aflatoxin catabolic process

description: The chemical reactions and pathways resulting in the breakdown of aflatoxin, a fungal metabolite found as a contaminant in moldy grains that induces liver cancer. Aflatoxin induces a G to T transversion at codon 249 of p53, leading to its inactivation. Aflatoxin is converted to a chemical carcinogen by P450.


mesodermal-endodermal cell signaling

description: Any process that mediates the transfer of information from mesodermal cells to endodermal cells.


indoleacetic acid metabolic process

description: The chemical reactions and pathways involving indole-3-acetic acid, a compound which functions as a growth regulator in plants.


queuosine metabolic process

description: The chemical reactions and pathways involving queuosines, any of a series of nucleosides found in tRNA and having an additional pentenyl ring added via an NH group to the methyl group of 7-methylguanosine. The pentenyl ring may carry other substituents.


name: oxidoreductase activity, acting on NAD(P)H

description: Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.


name: polyadenylation of viral mRNA by polymerase stuttering

description: Polyadenylation of viral mRNA through a polymerase stuttering mechanism. The stop signal present at the end of each gene comprises a stretch of uridine on which the viral polymerase acquires a stuttering behavior: after each adenine inserted, the polymerase moves back one nucleotide along with the mRNA. It resumes transcription adding a new adenine, then again moves back, thereby producing a polyA tail.


glycolipid metabolic process

description: The chemical reactions and pathways involving glycolipids, a class of 1,2-di-O-acylglycerols joined at oxygen 3 by a glycosidic linkage to a carbohydrate part (usually a mono-, di- or tri-saccharide). Some substances classified as bacterial glycolipids have the sugar group acylated by one or more fatty acids and the glycerol group may be absent.


galactose metabolic process

description: The chemical reactions and pathways involving galactose, the aldohexose galacto-hexose. D-galactose is widely distributed in combined form in plants, animals and microorganisms as a constituent of oligo- and polysaccharides; it also occurs in galactolipids and as its glucoside in lactose and melibiose.


adhesion of symbiont to host

description: The attachment of a symbiont to its host via either adhesion molecules, general stickiness, or other mechanisms. The host is defined as the larger of the organisms involved in a symbiotic interaction.


name: negative regulation of homotypic cell-cell adhesion

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of homotypic cell-cell adhesion.


name: collagen-activated tyrosine kinase receptor signaling pathway

description: The series of molecular signals initiated by collagen binding to its receptor on the surface of a target cell where the receptor possesses tyrosine kinase activity, and ending with the regulation of a downstream cellular process, e.g. transcription.


name: amino acid transmembrane transporter activity

description: Enables the transfer of amino acids from one side of a membrane to the other. Amino acids are organic molecules that contain an amino group and a carboxyl group.


positive regulation of cell activation

description: Any process that activates or increases the frequency, rate or extent of activation.


lactone biosynthetic process

description: The chemical reactions and pathways resulting in the formation of lactone.


plastid transcription

description: The synthesis of RNA from a plastid DNA template, usually by a specific plastid RNA polymerase.


name: neuron intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress

description: The series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a neuron. The pathway is induced in response to a stimulus indicating endoplasmic reticulum (ER) stress, and ends when the execution phase of apoptosis is triggered. ER stress usually results from the accumulation of unfolded or misfolded proteins in the ER lumen.


cellular response to salt

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a salt stimulus.


cytoplasmic helical capsid assembly

description: The assembly of a helical viral capsid in the cytoplasm. Occurs by assembling around the viral genome.


polythionate oxidation

description: The chemical reactions and pathways resulting in the conversion of thiosulfate to tetrathionate, using cytochrome c as an electron acceptor.


name: nuclear receptor-mediated mineralocorticoid signaling pathway

description: A nuclear receptor-mediated signaling pathway initiated by a mineralocorticoid binding to an intracellular receptor of the nuclear receptor protein family, and ending with regulation of a downstream cellular process, e.g. transcription.


name: 1-deoxy-D-xylulose 5-phosphate catabolic process

description: The chemical reactions and pathways resulting in the breakdown of 1-deoxy-D-xylulose 5-phosphate, the 5-phospho derivative of 1-deoxy-D-xylulose. 1-deoxy-D-xylulose 5-phosphate is an intermediate in the non-mevalonate pathway and a common precursor for isoprenoid, thiamin, and pyridoxol biosynthesis.


demethylkotanin biosynthetic process

description: The chemical reactions and pathways resulting in the formation of demethylkotanin.


GCA codon-amino acid adaptor activity

description: A triplet codon-amino acid adaptor activity that recognizes a GCA codon.


name: regulation of receptor signaling pathway via STAT

description: Any process that modulates the frequency, rate or extent of receptor signaling via STAT.


nuclear lncRNA surveillance

description: A process that identifies and degrades defective or aberrant lncRNAs within the nucleus.


name: cellular response to calcium ion starvation

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of calcium ions.


octadecene metabolic process

description: The chemical reactions and pathways involving octadecene.


galactarate biosynthetic process

description: The chemical reactions and pathways resulting in the formation of galactarate, the anion of galactaric acid.


name: symbiont genome ejection through host cell envelope, short tail mechanism

description: Entry of a symbiont's genome into the host cell through the host cell envelope via a short tail ejection system consisting a central tube, the connector which attaches the tail to the phage capsid and releases inner core proteins. Upon binding to the host cell surface, the phage displays a tube-like extension of its short tail that penetrates both host membranes. This tail extension comes from the release of viral core proteins with channel forming properties. Occurs in non-enveloped prokaryotic viruses.


involuntary skeletal muscle contraction

description: A process in which force is generated within involuntary skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. Involuntary skeletal muscle is skeletal muscle that is not under conscious control.


name: promoter clearance during DNA-templated transcription

description: Any process involved in the transition from the initiation to the elongation phases of transcription by a DNA-dependent RNA polymerase, generally including a conformational change from the initiation conformation to the elongation conformation. Promoter clearance often involves breaking contact with transcription factors involved only in the initiation phase and making contacts with elongation specific factors.


name: regulation of smooth muscle cell migration

description: Any process that modulates the frequency, rate or extent of smooth muscle cell migration.


name: positive regulation of interleukin-2-mediated signaling pathway

description: Any process that activates or increases the frequency, rate or extent of interleukin-2-mediated signaling pathway.


penetration of cumulus oophorus

description: The infiltration by sperm of the cumulus oophorus to reach the oocyte. The process involves digestive enzymes from a modified lysosome called the acrosome, situated at the head of the sperm.


inositol phosphate catabolic process

description: The chemical reactions and pathways resulting in the breakdown of an inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with one or more phosphate groups attached.


luteinizing hormone receptor activity

description: Combining with luteinizing hormone (also called lutropin) to initiate a change in cell activity.


glutaminyl-tRNA aminoacylation

description: The process of coupling glutamine to glutaminyl-tRNA, catalyzed by glutaminyl-tRNA synthetase. The glutaminyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2'-OH group of a glutamine-accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification.


hemicellulose catabolic process

description: The chemical reactions and pathways resulting in the breakdown of a hemicellulose.


protein mannosylation

description: The addition of a mannose residue to a protein acceptor molecule.


rhabdomere development

description: The assembly and arrangement of a rhabdomere within a cell. The rhabdomere is the organelle on the apical surface of a photoreceptor cell that contains the visual pigments.


quinolinate metabolic process

description: The chemical reactions and pathways involving quinolinate, the anion of quinolinic acid, also known as 2,3-pyridinedicarboxylic acid.


diaminopimelate metabolic process

description: The chemical reactions and pathways involving diaminopimelate, the anion of the dicarboxylic acid 2,6-diaminoheptanedioic acid. It is an intermediate in lysine biosynthesis and as a component (as meso-diaminopimelate) of the peptidoglycan of Gram-negative bacterial cell walls.


name: negative regulation of mesenchymal stem cell migration

description: Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal stem cell migration.


name: passive transmembrane transporter activity

description: Enables the transfer of a single solute from one side of a membrane to the other by a mechanism involving conformational change, either by facilitated diffusion or in a membrane potential dependent process if the solute is charged.


name: cellular response to vitamin B1 starvation

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of vitamin B1 (also called thiamin and thiamine).


regulation of leukocyte activation

description: Any process that modulates the frequency, rate, or extent of leukocyte activation.


plasma membrane organization

description: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the plasma membrane.


name: neurotransmitter receptor localization to postsynaptic specialization membrane

description: A process in which a neurotransmitter is transported to, or maintained in, a location within the membrane adjacent to a postsynaptic specialization (e.g. postsynaptic density).


Atg12 conjugating enzyme activity

description: Isoenergetic transfer of Atg12 from one protein to another via the reaction X-Atg12 + Y = Y-Atg12 + X, where both the X-Atg12 and Y-Atg12 linkages are thioester bonds between the C-terminal amino acid of Atg12 and a sulfhydryl side group of a cysteine residue.


phytoalexin catabolic process

description: The chemical reactions and pathways resulting in the breakdown of phytoalexins, any of a range of substances produced by plants as part of their defense response.


name: gastric inhibitory peptide signaling pathway

description: A G protein-coupled receptor signaling pathway initiated by gastric inhibitory peptide (GIP) binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.


name: positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator

description: Any process that activates or increases the frequency, rate or extent of intrinsic apoptotic signaling pathway by p53 class mediator.


peptidyl-serine palmitoylation

description: The covalent attachment of a palmitoyl group to an oxygen (O) atom in a serine residue to form peptidyl-O-palmitoyl-L-serine.


response to fungus

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a fungus.


name: cell chemotaxis to vascular endothelial growth factor

description: The directed movement of a motile cell in response to the presence of vascular endothelial growth factor (VEGF).


name: positive regulation of prostaglandin catabolic process

description: Any process that activates or increases the frequency, rate or extent of prostaglandin catabolic process.


response to host osmotic environment

description: Any process that results in a change in state or activity of the symbiont or its cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the osmotic conditions in or around its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.


description: Catalysis of the transfer of galactose from UDP-galactose to hydroxyproline residues present in the peptide backbone.


name: symbiont entry into host cell via permeabilization of inner membrane

description: The entry of a symbiont into the cytoplasm of a host cell, following fusion with the outer membrane, via permeabilization of the plasma (inner) membrane. This process mediates the entry of some non-enveloped viruses into prokaryotic cells. In the case of some double stranded RNA viruses of prokaryotes this occurs via interaction of a membrane-interacting component of the capsid, leading to depolarization and permeabilization of the plasma membrane.


name: cellular response to environmental stimulus

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an environmental stimulus.


name: secondary metabolite biosynthetic process

description: The chemical reactions and pathways resulting in the formation of secondary metabolites, the compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon.


xyloglucan catabolic process

description: The chemical reactions and pathways resulting in the breakdown of a xyloglucan.


name: positive regulation of secretion by cell

description: Any process that activates or increases the frequency, rate or extent of secretion by cell.


histone H4 demethylase activity

description: Catalysis of the removal of a methyl group from a modified lysine residue of the histone H4 protein. This is a dioxygenase reaction that is dependent on Fe(II) and 2-oxoglutarate.


cyclopentanol metabolic process

description: The chemical reactions and pathways involving cyclopentanol.


name: cell wall beta-glucan biosynthetic process

description: The chemical reactions and pathways resulting in the formation of beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of cells.


name: peptidyl-L-3-oxoalanine biosynthetic process from peptidyl-cysteine or peptidyl-serine

description: The modification of peptidyl-cysteine or peptidyl-serine to peptidyl-L-3-oxoalanine; characteristic of the active sites of arylsulfatases.


T-tubule organization

description: A process that is carried out at the cellular level that results in the assembly, arrangement of constituent parts, or disassembly of the T-tubule. A T-tubule is an invagination of the plasma membrane of a muscle cell that extends inward from the cell surface around each myofibril.


leptin-mediated signaling pathway

description: The series of molecular signals initiated by leptin binding to its receptor on the surface of a cell, and ending with the regulation of a downstream cellular process, e.g. transcription. Leptin is a hormone manufactured primarily in the adipocytes of white adipose tissue, and the level of circulating leptin is directly proportional to the total amount of fat in the body.


oxytocin receptor activity

description: Combining with oxytocin to initiate a change in cell activity.


name: positive regulation of adenylate cyclase-inhibiting opioid receptor signaling pathway

description: Any process that activates or increases the frequency, rate or extent of adenylate cyclase-inhibiting opioid receptor signaling pathway.


octopine metabolic process

description: The chemical reactions and pathways involving octopine, (N-(1-carboxy-4-guanidinobutyl)-L-alanine), an amino acid derived opine.


name: glutamate catabolic process to succinate via 2-oxoglutarate-dependent GABA-transaminase activity

description: The chemical reactions and pathways resulting in the breakdown of glutamate into succinate, that includes the conversion of 4-aminobutyrate to succinate semialdehyde by the 2-oxoglutarate-dependent gamma aminobutyrate (GABA) transaminase.


CAAX-box protein maturation

description: A series of specific posttranslational modifications to the CAAX box region of CAAX box proteins. CAAX box proteins are eukaryotic proteins that contain a CAAX motif where the C is a cysteine, the two A residues are aliphatic amino acids and the X can be one of several amino acids. The CAAX-box proteins undergo three sequential, enzymatic, post-translational modifications essential to their targeting: First, the proteins are prenylated by one of two prenyltransferases called farnesyltransferase and geranylgeranyltransferase-I. Prenylation results in the covalent attachment of either farnesyl or geranylgeranyl isoprenoid groups to the cysteine in the CAAX box motif. Prenylation is followed by proteolytic removal of the last three amino acids of the protein (AAX). Finally, the newly exposed carboxylate group of the isoprenylcysteine is methylated by an ER-associated prenyl-dependent carboxylmethyltransferase.


name: cellular response to hydrostatic pressure

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrostatic pressure stimulus. Hydrostatic pressure is the force acting on an object in a system where the fluid is at rest (as opposed to moving). The weight of the fluid above the object creates pressure on it.


pH-gated sodium channel activity

description: A gated channel activity that enables the transmembrane transfer of a sodium ion by a channel that opens in response to a change in pH.


name: symbiont-mediated inactivation of host ribosome

description: A process in which a symbiont inhibits or disrupts translation of mRNA into protein in its host by inactivating its ribosomes.


protein localization to cell tip

description: A process in which a protein is transported to, or maintained in, a location at the cell tip.


name: symbiont-mediated suppression of host type II interferon-mediated signaling pathway

description: A process in which a symbiont interferes with, inhibits or disrupts a type II interferon-mediated signaling in the host organism. Type II interferon is also known as interferon-gamma.


nitrogen cycle metabolic process

description: A nitrogen compound metabolic process that contributes to the nitrogen cycle. The nitrogen cycle is a series of metabolic pathways by which nitrogen is converted between various forms and redox states; it encompasses pathways in which nitrogen is acted upon directly, such as nitrification, denitrification, nitrogen fixation, and mineralization.


name: mesenchymal-endodermal cell signaling involved in lung induction

description: Any process that mediates the transfer of information from a mesenchymal cell to an endodermal cell in the foregut and contributes to the formation of the lung bud.


cellular response to Gentian violet

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a Gentian violet stimulus.


name: regulation of mononuclear cell migration

description: Any process that modulates the rate, frequency or extent of mononuclear cell migration. Mononuclear cell migration is the movement of a mononuclear cell within or between different tissues and organs of the body.


bacitracin A catabolic process

description: The chemical reactions and pathways resulting in the breakdown of bacitracin A.


alkylthioltransferase activity

description: Catalysis of the transfer of an alkylthio group from one compound (donor) to another (acceptor).


name: negative regulation of cholesterol metabolic process

description: Any process that decreases the rate, frequency, or extent of cholesterol metabolism, the chemical reactions and pathways involving cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.


regulation of pectin catabolic process

description: Any process that modulates the frequency, rate or extent of pectin catabolic process.


name: protein localization to adherens junction

description: Any process in which a protein is transported to, and/or maintained at the adherens junction.


response to bacteriocin

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bacteriocin stimulus. A bacteriocin is a protein substance released by certain bacteria that kills but does not lyse closely related strains of bacteria. Specific bacteriocins attach to specific receptors on cell walls and induce specific metabolic block, e.g. cessation of nucleic acid or protein synthesis of oxidative phosphorylation.


central B cell deletion

description: The deletion of B cells by apoptotic process occurring as part of central tolerance induction and B cell selection.


cresol catabolic process

description: The chemical reactions and pathways resulting in the breakdown of cresol, a mixture of the aromatic alcohol isoforms o-, p-, and m-cresol, which is obtained from coal tar or petroleum. The isomers are used as disinfectants, textile scouring agents, surfactants and as intermediates in the manufacture of salicylaldehyde, coumarin, and herbicides as well as being a major component of creosote.


name: intracellularly ATP-gated chloride channel activity

description: Enables passage of a chloride ion through a transmembrane channel that opens when ATP is bound by the channel complex or one of its constituent parts on the intracellular side of the plasma membrane.


regulation of cell communication

description: Any process that modulates the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.


description: Catalysis of the transfer of an alpha-D-mannosyl residue from GDP-mannose into lipid-linked oligosaccharide, forming an alpha-(1->6)-D-mannosyl-D-mannose linkage.


name: symbiont-mediated suppression of host immune response

description: A process in which a symbiont interferes with, inhibits or disrupts the normal execution of an immune response of the host organism. The immune response is any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat. The host is defined as the larger of the organisms involved in a symbiotic interaction.


name: leukemia inhibitory factor signaling pathway

description: The series of molecular signals initiated by the binding of a leukemia inhibitory factor to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.


sterol biosynthetic process

description: The chemical reactions and pathways resulting in the formation of sterols, steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule.


description: Catalysis of the reaction: acetyl-CoA + aminoglycoside = CoA + 1-N-acetylaminoglycoside. This is acetylation of the 1-amino group of the central deoxystreptamine ring.


flavin prenyltransferase activity

description: Catalysis of the reaction: dimethylallylphosphate + FMNH2 = prenylated FMNH2 + phosphate.


name: negative regulation of SREBP signaling pathway

description: Any process that stops, prevents or reduces the frequency, rate or extent of the SREBP signaling pathway.


tRNA C5-cytosine methylation

description: The process whereby a cytosine in a tRNA is methylated at position 5 of the cytosine.


menaquinone catabolic process

description: The chemical reactions and pathways resulting in the breakdown of menaquinones, any of the quinone-derived compounds synthesized by intestinal bacteria. Structurally, menaquinones consist of a methylated naphthoquinone ring structure and side chains composed of a variable number of unsaturated isoprenoid residues. Menaquinones have vitamin K activity and are known as vitamin K2.


DNA modification

description: The covalent alteration of one or more nucleotide sites in DNA, resulting in a change in its properties.


name: transcription-coupled nucleotide-excision repair, DNA damage recognition

description: The identification of lesions on the actively transcribed strand of the DNA duplex as well as a small subset of lesions not recognized by the general nucleotide-excision repair pathway.


dicarboxylic acid catabolic process

description: The chemical reactions and pathways resulting in the breakdown of dicarboxylic acids, any organic acid containing two carboxyl (-COOH) groups.


name: protein localization to T cell secretory granule

description: A process in which a protein is transported to, or maintained in, a location within a secretory granule in a T cell.


name: positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell

description: Any process that activates or increases the frequency, rate or extent of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell.


interleukin-16 receptor activity

description: Combining with interleukin-16 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


endocrocin biosynthetic process

description: The chemical reactions and pathways resulting in the formation of endocrocin.


autophagosome membrane disassembly

description: The controlled breakdown of the membranes of autophagosomes.


name: regulation of prostaglandin catabolic process

description: Any process that modulates the frequency, rate or extent of prostaglandin catabolic process.


name: positive regulation of Kit signaling pathway

description: Any process that activates or increases the frequency, rate or extent of Kit signaling pathway.


name: positive regulation of complement activation, lectin pathway

description: Any process that activates or increases the frequency, rate or extent of complement activation by the lectin pathway.


macromolecule catabolic process

description: The chemical reactions and pathways resulting in the breakdown of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.


name: cellular response to methamphetamine hydrochloride

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methamphetamine hydrochloride stimulus.


name: regulation of toll-like receptor 15 signaling pathway

description: Any process that modulates the frequency, rate or extent of toll-like receptor 15 signaling pathway.


Cvt vesicle assembly

description: A vesicle organization process that takes place as part of the Cvt pathway, and results in the formation of a double membrane-bounded cytosolic structure that sequesters precursor aminopeptidase I (prAPI).


name: regulation of interleukin-2-mediated signaling pathway

description: Any process that modulates the frequency, rate or extent of interleukin-2-mediated signaling pathway.


name: symbiont entry into host cell via permeabilization of host membrane

description: The entry of a symbiont into the cytoplasm of a host cell, triggered by an interaction between the bilayer of a host membrane and a membrane-penetration symbiont protein. This process mediates the entry of some non-enveloped virus into host cells, and results in the release of the virus contents into the host cell cytoplasm.


name: regulation of proanthocyanidin biosynthetic process

description: Any process that modulates the frequency, rate or extent of proanthocyanidin biosynthetic process.


cytochrome complex assembly

description: The aggregation, arrangement and bonding together of a cytochrome complex. A cytochrome complex is a protein complex in which at least one of the proteins is a cytochrome, i.e. a heme-containing protein involved in catalysis of redox reactions.


name: positive regulation of ATF6-mediated unfolded protein response

description: Any process that activates or increases the frequency, rate or extent of the ATF6-mediated unfolded protein response.


cholesterol catabolic process

description: The chemical reactions and pathways resulting in the breakdown of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.


protein-containing complex disassembly

description: The disaggregation of a protein-containing macromolecular complex into its constituent components.


vesicle fusion with vesicle

description: Fusion of the membrane of a transport vesicle with a target membrane on another vesicle.


cGMP catabolic process

description: The chemical reactions and pathways resulting in the breakdown of cyclic GMP, guanosine 3',5'-phosphate.


name: regulation of mRNA alternative polyadenylation

description: Any process that modulates the frequency, rate or extent of mRNA alternative polyadenylation.


name: negative regulation of N',N'',N'''-triacetylfusarinine C biosynthetic process

description: Any process that stops, prevents or reduces the frequency, rate or extent of N',N'',N'''-triacetylfusarinine C biosynthetic process.


demethylase activity

description: Catalysis of the removal of a methyl group from a substrate.


name: oxidation-dependent protein catabolic process

description: The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the oxidation of one or more amino acid residues in the protein.


name: regulation of intrinsic apoptotic signaling pathway in response to osmotic stress

description: Any process that modulates the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to osmotic stress.


melatonin receptor activity

description: Combining with melatonin, N-acetyl-5-methoxytryptamine, to initiate a change in cell activity. Melatonin is a neuroendocrine substance that stimulates the aggregation of melanosomes in melanophores, thus lightening the skin.


name: positive regulation of tumor necrosis factor-mediated signaling pathway

description: Any process that activates or increases the frequency, rate or extent of tumor necrosis factor-mediated signaling pathway.


hemoglobin biosynthetic process

description: The chemical reactions and pathways resulting in the formation of hemoglobin, an oxygen carrying, conjugated protein containing four heme groups and globin.


name: glutamine family amino acid biosynthetic process

description: The chemical reactions and pathways resulting in the formation of amino acids of the glutamine family, comprising arginine, glutamate, glutamine and proline.


name: diphthine methyl ester synthase activity

description: Catalysis of the reaction: 2-[(3S)-amino-3-carboxypropyl]-L-histidyl-[translation elongation factor 2] + 4 S-adenosyl-L-methionine = diphthine methyl ester-[translation elongation factor 2] + 3 H+ + 4 S-adenosyl-L-homocysteine.


methanophenazine biosynthetic process

description: The chemical reactions and pathways resulting in the formation of methanophenazine.


name: protein localization to mitotic spindle pole body

description: A process in which a protein is transported to, or maintained in, a location within a mitotic spindle pole body.


p-cymene catabolic process

description: The chemical reactions and pathways resulting in the breakdown of p-cymene, 1-methyl-4-isopropylbenzene, one of the alkyl-substituted aromatic hydrocarbons found in volatile oils from over 100 plants.


name: symbiont-mediated perturbation of host cell cycle G1/S transition checkpoint

description: A process in which a symbiont interferes with the normal execution of the host cell G1/S transition checkpoint. The host is defined as the larger of the organisms involved in a symbiotic interaction.


name: non-recombinational interstrand cross-link repair

description: Removal of a DNA interstrand crosslink (a covalent attachment of DNA bases on opposite strands of the DNA) and restoration of the DNA by a mechanism that does not involve homologous DNA recombination.


toluene-4-sulfonate metabolic process

description: The chemical reactions and pathways involving toluene-4-sulfonate, the anion of 4-toluene sulfonic acid, a white crystalline solid which is highly hygroscopic and soluble in water.


hopanoid metabolic process

description: The chemical reactions and pathways involving hopanoids, pentacyclic sterol-like compounds based on the hopane nucleus.


response to host defenses

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detecting the defenses of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.


name: organonitrogen compound biosynthetic process

description: The chemical reactions and pathways resulting in the formation of organonitrogen compound.


establishment of protein localization

description: The directed movement of a protein to a specific location.


name: iron incorporation into iron-sulfur cluster via tetrakis-L-cysteinyl triiron tetrasulfide

description: The incorporation of iron into a 3Fe-4S iron-sulfur cluster via tetrakis-L-cysteinyl triiron tetrasulfide.


name: regulation of (1->3)-beta-D-glucan metabolic process

description: Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving (1->3)-beta-D-glucans.


name: sensory perception of mechanical stimulus

description: The series of events required for an organism to receive a sensory mechanical stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.


cellular response to vitamin B3

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin B3 stimulus.


description: The chemical reactions and pathways involving (-)-exo-alpha-bergamotene.


name: phosphatidylcholine biosynthesis from phosphoryl-ethanolamine via N-dimethylethanolamine phosphate and CDP-choline

description: The phosphatidylcholine biosynthetic process that begins with three consecutive N-methylation steps that are carried out on phospho-bases, phosphoethanolamine, phospho-N-methylethanolamine, and phospho-N-dimethylethanolamine; the process ends with the conversion of a phosphatidyl-N-dimethylethanolamine to a phosphatidylcholine.


malate metabolic process

description: The chemical reactions and pathways involving malate, the anion of hydroxybutanedioic acid, a chiral hydroxydicarboxylic acid. The (+) enantiomer is an important intermediate in metabolism as a component of both the TCA cycle and the glyoxylate cycle.


carbon fixation by acetyl-CoA pathway

description: A pathway of carbon dioxide fixation in which one molecule of acetyl-CoA is completely synthesized from two molecules of carbon dioxide (CO2).


T cell extravasation

description: The migration of a T cell from the blood vessels into the surrounding tissue.


globoside metabolic process

description: The chemical reactions and pathways involving globosides, globotetraosylceramides, ceramides containing a core structure of GalNAc-beta-(1->3)-Gal-alpha-(1->4)-Glc(I). Globosides are the major neutral glycosphingolipid in normal kidneys and erythrocytes.


mitochondrial membrane organization

description: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a mitochondrial membrane, either of the lipid bilayer surrounding a mitochondrion.


strigolactone biosynthetic process

description: The chemical reactions and pathways resulting in the formation of strigolactone.


name: immunoglobulin production in mucosal tissue

description: The synthesis and release of immunoglobulin in the mucosal tissue.


purine deoxyribonucleoside salvage

description: Any process which produces a purine deoxyribonucleoside from derivatives of it, without de novo synthesis.


name: cell wall (1->3)-alpha-glucan biosynthetic process

description: The chemical reactions and pathways resulting in the formation of (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-glucosidic bonds, found in the walls of cells.


zymogen activation

description: The proteolytic processing of an inactive enzyme to an active form.


macrophage cytokine production

description: The appearance of a macrophage cytokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


name: mitochondria-associated ubiquitin-dependent protein catabolic process

description: The chemical reactions and pathways resulting in the breakdown of proteins transported from mitochondria and targeted to cytoplasmic proteasomes for degradation as a response to oxidative stress conditions.


glycosylation

description: The covalent attachment and further modification of carbohydrate residues to a substrate molecule.


name: circadian regulation of heart rate by the suprachiasmatic nucleus

description: The process in which the suprachiasmatic nucleus modulates heart rate at different values with a regularity of approximately 24 hours.


name: protein-heme P460 linkage via heme P460-bis-L-cysteine-L-tyrosine

description: The linkage of protein to heme P460 via heme P460-bis-L-cysteine-L-tyrosine.


B cell apoptotic process

description: Any apoptotic process in a B cell, a lymphocyte of B lineage with the phenotype CD19-positive and capable of B cell mediated immunity.


cellular response to indole-3-methanol

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an indole-3-methanol stimulus.


name: tricarboxylate secondary active transmembrane transporter activity

description: Enables the transfer of tricarboxylate from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters.


name: inositol diphosphate pentakisphosphate diphosphatase activity

description: Catalysis of the reaction: diphospho-1D-myo-inositol pentakisphosphate + H2O = 1D-myo-inositol hexakisphosphate + phosphate.


U7 snRNA binding

description: Binding to a U7 small nuclear RNA (U7 snRNA).


estrous cycle

description: A type of ovulation cycle, which occurs in most mammalian therian females, where the endometrium is resorbed if pregnancy does not occur.


regulation of motor neuron migration

description: Any process that modulates the frequency, rate or extent of motor neuron migration.


negative regulation of glucose import

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the import of the hexose monosaccharide glucose into a cell or organelle.


name: nucleotide-excision repair involved in interstrand cross-link repair

description: Any nucleotide-excision repair that is involved in interstrand cross-link repair.


cellular response to histamine

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a histamine stimulus. Histamine, the biogenic amine 2-(1H-imidazol-4-yl)ethanamine, is involved in local immune responses as well as regulating physiological function in the gut and acting as a neurotransmitter.


flavone apiosyltransferase activity

description: Catalysis of the reaction: UDP-apiose + 7-O-beta-D-glucosyl-5,7,4'-trihydroxyflavone = UDP + 7-O-(beta-D-apiofuranosyl-1,2-beta-D-glucosyl)-5,7,4'-trihydroxyflavone.


regulation of cytokinesis

description: Any process that modulates the frequency, rate or extent of the division of the cytoplasm of a cell and its separation into two daughter cells.


presynapse to nucleus signaling pathway

description: The series of molecular signals that conveys information from the presynapse to the nucleus via cytoskeletal transport of a protein from a presynapse to the component to the nucleus where it affects biochemical processes that occur in the nucleus (e.g DNA transcription, mRNA splicing, or DNA/histone modifications).


protein localization to trailing edge

description: A process in which a protein is transported to, or maintained at, the trailing edge. The trailing edge is the area of a motile cell opposite to the direction of movement.


name: regulation of phenazine biosynthetic process

description: Any process that modulates the frequency, rate or extent of phenazine biosynthetic process.


vacuolar protein processing

description: Protein processing that takes place in the vacuole. Most protein processing in the vacuole represents proteolytic cleavage of precursors to form active enzymes.


lymphocyte migration into lymph node

description: The movement of a lymphocyte within the lymphatic system into a lymph node, and its subsequent positioning within defined functional compartments such as sites of cell activation by antigen.


name: negative regulation of Wnt signaling pathway, planar cell polarity pathway

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the Wnt signaling pathway, planar cell polarity pathway.


name: cellular response to decreased oxygen levels

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting a decline in the level of oxygen.


L-arabinose biosynthetic process

description: The chemical reactions and pathways resulting in the formation of L-arabinose, arabino-pentose.


name: ubiquitin-like protein transferase activity

description: Catalysis of the transfer of a ubiquitin-like from one protein to another via the reaction X-ULP + Y = Y-ULP + X, where both X-ULP and Y-ULP are covalent linkages. ULP represents a ubiquitin-like protein.


description: The methylation of the N-terminal phenylalanine of proteins to form the derivative N-methyl-L-phenylalanine.


'de novo' CTP biosynthetic process

description: The chemical reactions and pathways resulting in the formation of cytidine 5'-triphosphate (CTP) from simpler components.


name: histone H4K16 acetyltransferase activity

description: Catalysis of the reaction: acetyl-CoA + histone H4 L-lysine (position 16) = CoA + histone H4 N6-acetyl-L-lysine (position 16). This reaction represents the addition of an acetyl group to the lysine at position 16 of histone H4.


GGU codon-amino acid adaptor activity

description: A triplet codon-amino acid adaptor activity that recognizes a GGU codon.


description: The chemical reactions and pathways resulting in the breakdown of N(omega),N(omega)-dimethyl-L-arginine, a methyl-L-arginine having two methyl groups both attached to the primary amino moiety of the guanidino group.


dimethyl ether metabolic process

description: The chemical reactions and pathways involving dimethyl ether, CH3-O-CH3, the simplest ether. Dimethyl ether, also known wood ether and methyl ether, is a colorless gas that has been used in refrigeration applications.


name: positive regulation of peptidoglycan recognition protein signaling pathway

description: Any process that increases the rate, frequency, or extent of the peptidoglycan recognition protein signaling pathway.


name: glucosylglycerol transmembrane transporter activity

description: Enables the transfer of a glucosylglycerol from one side of a membrane to the other. A glucosylglycerol is an alpha-D-glucopyranosyl-alpha-(1,2)-glycerol.


name: modulation of blood pressure in another organism

description: A process by which one organism modulates the force with which blood travels through the circulatory system of another organism.


GGC codon-amino acid adaptor activity

description: A triplet codon-amino acid adaptor activity that recognizes a GGC codon.


name: positive regulation of methanophenazine biosynthetic process

description: Any process that activates or increases the frequency, rate or extent of methanophenazine biosynthetic process.


codeine metabolic process

description: The chemical reactions and pathways involving codeine, an alkaloid found in the opium poppy, Papaver somniferum var. album. Codeine has analgesic, anti-tussive and anti-diarrhoeal properties.


name: isopentenyl diphosphate biosynthetic process, mevalonate pathway involved in terpenoid biosynthetic process

description: The chemical reactions and pathways resulting in the formation of isopentenyl diphosphate by the mevalonate pathway that contributes to terpenoid biosynthesis. This pathway converts acetate, in the form of acetyl-CoA, to isopentenyl diphosphate (IPP) through a series of mevalonate intermediates.


name: heparan sulfate N-acetylglucosaminyltransferase activity

description: Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + heparan sulfate = UDP + (N-acetyl-D-glucosaminyl)-heparan sulfate.


tetraterpenoid catabolic process

description: The chemical reactions and pathways resulting in the breakdown of tetraterpenoid compounds, terpenoids with eight isoprene units.


fatty acid derivative catabolic process

description: The chemical reactions and pathways resulting in the breakdown of fatty acid derivative.


sodium-dependent self proteolysis

description: The sodium-dependent hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their own peptide bonds.


name: negative regulation of Wnt signaling pathway, calcium modulating pathway

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors leads to an increase in intracellular calcium and activation of protein kinase C (PKC).


regulation of miRNA metabolic process

description: Any process that modulates the frequency, rate or extent of miRNA metabolic process.


name: acetate transmembrane transporter activity

description: Enables the transfer of acetate from one side of a membrane to the other. Acetate is the 2-carbon carboxylic acid ethanoic acid.


auxin conjugate metabolic process

description: The chemical reactions and pathways involving auxin conjugates, a bound form of auxin.


name: benzene-containing compound metabolic process

description: The chemical reactions and pathways involving benzene, C6H6, a volatile, very inflammable liquid, contained in the naphtha produced by the destructive distillation of coal, from which it is separated by fractional distillation, or any of its derivatives.


S-methylmethionine biosynthetic process

description: The chemical reactions and pathways resulting in the formation of S-methyl-methionine (SMM) from methionine and S-adenosyl-methionine (Ado-Met), catalyzed by methionine S-methyltransferase (MMT). SMM can be reconverted to methionine by donating a methyl group to homocysteine, and concurrent operation of this reaction and that mediated by MMT sets up the SMM cycle.


D-xylose fermentation

description: The anaerobic enzymatic conversion of D-xylose to ethanol, yielding energy in the form of ATP.


name: negative regulation of toll-like receptor signaling pathway

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor signaling pathway.


name: iron incorporation into iron-sulfur cluster via tris-L-cysteinyl L-cysteine persulfido L-glutamato L-histidino L-serinyl nickel triiron disulfide trioxide

description: The incorporation of iron into a 3Fe-2S cluster by tris-L-cysteinyl L-cysteine persulfido L-glutamato L-histidino L-serinyl nickel triiron disulfide trioxide.


helper T cell diapedesis

description: The passage of a helper T cell between the tight junctions of endothelial cells lining blood vessels, typically the fourth and final step of cellular extravasation.


myeloid leukocyte migration

description: The movement of a myeloid leukocyte within or between different tissues and organs of the body.


amide metabolic process

description: The chemical reactions and pathways involving an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group, as carried out by individual cells.


cellular response to heparin

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heparin stimulus.


name: cyclization of glutamine involved in intein-mediated protein splicing

description: The cyclization of glutamine to yield an L-glutamimide residue at the C-terminus of an excised intein during protein splicing.


name: symbiont-mediated perturbation of host tight cell-cell junction

description: The process in which an organism effects a change that impairs the structure or temporarily subverts the tight cell-cell junctions between cells of the host. Tight cell-cell junctions, a cell-cell junction that seals cells together in an epithelium in a way that prevents even small molecules from leaking from one side of the sheet to the other.


name: DNA double-strand break processing involved in repair via single-strand annealing

description: The 5' to 3' exonucleolytic resection of the DNA at the site of the break to form a 3' single-strand DNA overhang that results in the repair of a double strand break via single-strand annealing.


apiose metabolic process

description: The chemical reactions and pathways involving apiose, the branched tetrose 3-C-(hydroxymethyl)-D-glycero-tetrose.


name: regulation of catecholamine metabolic process

description: Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving catecholamines.


histone H3R8 methyltransferase activity

description: Catalysis of the reaction: S-adenosyl-L-methionine + (histone H3)-arginine (position 8) = S-adenosyl-L-homocysteine + (histone H3-N-methyl-arginine (position 8). This reaction is the addition of a methyl group to the arginine residue at position 8 of histone H3.


name: positive regulation of cardiac muscle cell differentiation

description: Any process that activates or increases the frequency, rate or extent of cardiac muscle cell differentiation.


name: histone H4K12 methyltransferase activity

description: Catalysis of the reaction: S-adenosyl-L-methionine + histone H4 L-lysine (position 12) = S-adenosyl-L-homocysteine + histone H4 N6-methyl-L-lysine (position 12). This reaction is the addition of a methyl group to the lysine residue at position 12 of the histone H4 protein.


heme a metabolic process

description: The chemical reactions and pathways involving heme a, a derivative of heme found in cytochrome aa3.


name: histamine-gated chloride channel activity

description: Enables the energy-independent facilitated diffusion of a chloride ion through a transmembrane channel that opens when bound to histamine.


name: nucleoside triphosphate diphosphatase activity

description: Catalysis of the reaction: a nucleoside triphosphate + H2O = a nucleotide + H+ + diphosphate.


sperm DNA decondensation

description: Unwinding of the condensed nuclear chromatin of an inactive male pronucleus after fertilization.


name: negative regulation of astrocyte chemotaxis

description: Any process that stops, prevents or reduces the frequency, rate or extent of astrocyte chemotaxis.


T cell secretory granule organization

description: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a secretory granule in a T cell. A secretory granule is a small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion.


name: alpha-linked polysaccharide catabolism to maltotriose

description: The breakdown of large alpha-linked polysaccharides by hydrolysis of (1->4)-alpha-D-glucosidic linkages to yield maltotriose.


name: intracellular monoatomic cation homeostasis

description: A homeostatic process involved in the maintenance of a steady state level of monoatomic cations within a cell. Monatomic cations (also called simple cations) are cations consisting of exactly one atom.


name: protein N-linked glycosylation via tryptophan

description: The glycosylation of protein via peptidyl-tryptophan, 1'-glycosyl-L-tryptophan; results in the formation of an (S)-2-amino-3-(1-D-mannopyranosyloxy-1H-indol-3-yl)propanoic acid residue.


zymosterol biosynthetic process

description: The chemical reactions and pathways resulting in the formation of zymosterol, (5alpha-cholesta-8,24-dien-3beta-ol).


protein K48-linked ubiquitination

description: A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 48 of the ubiquitin monomers, is added to a protein. K48-linked ubiquitination targets the substrate protein for degradation.


interferon-alpha production

description: The appearance of interferon-alpha due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


mRNA m(6)A methyltransferase activity

description: Catalysis of the reaction: an adenosine in mRNA + S-adenosyl-L-methionine = an N(6)-methyladenosine in mRNA + H+ + S-adenosyl-L-homocysteine. This activity is the methylation of adenines in mRNA with the consensus sequence RRACH, where R is a purine, and H is C, A, or U.


protein-heme linkage via 3'-L-histidine

description: The covalent linkage of heme and a protein via 3'-L-histidine (otherwise known as pi-heme-histidine, pros-heme-histidine).


retinoic acid catabolic process

description: The chemical reactions and pathways resulting in the breakdown of retinoic acid, one of the three components that makes up vitamin A.


DNA excision

description: The removal of a section of DNA from a larger DNA molecule by the making of dual incisions that flank the section to be excised.


name: regulation of multicellular organismal development

description: Any process that modulates the frequency, rate or extent of multicellular organismal development.


name: mitochondrial respiratory chain complex assembly

description: The aggregation, arrangement and bonding together of a set of components to form a mitochondrial respiratory chain complex.


sphingomyelin metabolic process

description: The chemical reactions and pathways involving sphingomyelin, N-acyl-4-sphingenyl-1-O-phosphorylcholine, any of a class of phospholipids in which the amino group of sphingosine is in amide linkage with one of several fatty acids, while the terminal hydroxyl group of sphingosine is esterified to phosphorylcholine.


description: The chemical reactions and pathways involving 5,6,7,8-tetrahydromethanopterin.


name: lysine biosynthetic process via diaminopimelate and L-2-acetamido-6-oxoheptanedioate

description: The chemical reactions and pathways resulting in the formation of lysine, via the intermediates diaminopimelate and L-2-acetamido-6-oxoheptanedioate; in this pathway tetrahydrodipicolinate is converted to meso-diaminopimelate in four enzymatic steps.


name: symbiont-mediated suppression of host interferon-mediated signaling pathway

description: Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of interferon-mediated signaling in the host organism.


name: activation of prostate induction by androgen receptor signaling pathway

description: The series of molecular signals initiated by androgen binding to its receptor in the urogenital sinus mesenchyme that initiates prostate induction. Prostate induction is the close range interaction of the urogenital sinus mesenchyme and the urogenital sinus epithelium that causes the cells of the urogenital sinus epithelium to change their fates and specify the development of the prostate gland.


name: protein modification by small protein conjugation or removal

description: A protein modification process in which one or more groups of a small protein, such as ubiquitin or a ubiquitin-like protein, are covalently attached to or removed from a target protein.


name: endoplasmic reticulum cisternal network maintenance

description: The organization process that preserves the endoplasmic reticulum (ER) cisternal network in a stable functional or structural state. The ER cisternal network is the ER part that comprises the membranes with low curvature in cross-section.


GSI anchor metabolic process

description: The chemical reactions and pathways involving glycosylsphingolipidinositol (GSI) anchors, which attach membrane proteins to the lipid bilayer of the cell membrane.


spermine metabolic process

description: The chemical reactions and pathways involving spermine, a polybasic amine found in human sperm, in ribosomes and in some viruses, which is involved in nucleic acid packaging. Synthesis is regulated by ornithine decarboxylase which plays a key role in control of DNA replication.


ribosome disassembly

description: The disaggregation of a ribosome into its constituent components; includes the dissociation of ribosomal subunits.


name: positive regulation of toll-like receptor 9 signaling pathway

description: Any process that activates or increases the frequency, rate, or extent of toll-like receptor 9 signaling pathway.


cellular response to monoamine stimulus

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monoamine stimulus. A monoamine is any of a group of molecular messengers that contain one amino group that is connected to an aromatic ring by ethylene group (-CH2-CH2-). Monoamines are derived from the aromatic amino acids phenylalanine, tyrosine, histidine and tryptophan.


ciliary pro-basal body maturation

description: A process that is carried out at the cellular level which results in the conversion of an immature and partially assembled ciliary pro-basal body into a mature basal body that is capable of nucleating a cilium.


name: negative regulation of hepatocyte apoptotic process

description: Any process that stops, prevents or reduces the frequency, rate or extent of hepatocyte apoptotic process.


name: negative regulation of starch metabolic process

description: Any process that stops, prevents or reduces the frequency, rate or extent of starch metabolic process.


name: regulation of flavonol biosynthetic process

description: Any process that modulates the frequency, rate or extent of flavonol biosynthetic process.


name: cyclization of asparagine involved in intein-mediated protein splicing

description: The cyclization of asparagine to yield an L-aspartimide (otherwise known as alpha-aminosuccinimide) residue at the C-terminus of an excised intein during protein splicing.


name: iron incorporation into iron-sulfur cluster via tetrakis-L-cysteinyl diiron disulfide

description: The incorporation of iron into a 2Fe-2S iron-sulfur cluster via tetrakis-L-cysteinyl diiron disulfide.


O antigen metabolic process

description: The chemical reactions and pathways involving the O side chain of a lipopolysaccharide, which determines the antigenic specificity of the organism. It is made up of about 50 repeating units of a branched tetrasaccharide.


name: mitotic recombination-dependent replication fork processing

description: Replication fork processing that includes recombination between DNA near the arrested fork and homologous sequences. Proteins involved in homologous recombination are required for replication restart.


HRI-mediated signaling

description: A series of reactions in which a signal is passed on to downstream proteins within the cell via HRI (also known as EIF2AK1), an intracellular protein kinase that is activated by stress signals, such as heme deficiency, oxidative stress, osmotic shock, mitochondrial dysfunction and heat shock.


intestinal lipid catabolic process

description: The chemical reactions and pathways resulting in the breakdown into fatty acids and monoglycerides of lipids in the small intestine. Lipids are broken down by lipases released by the pancreas.


cytokine receptor activity

description: Combining with a cytokine and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


peptidyl-threonine decanoylation

description: The decanoylation of peptidyl-threonine to form peptidyl-O3-decanoyl-L-threonine, typical of the protein ghrelin.


luteinizing hormone signaling pathway

description: A G protein-coupled receptor signaling pathway initiated by luteinizing hormone binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process.


name: spermidine:coumaroyl CoA N-acyltransferase activity

description: Catalysis of the transfer of a coumaroyl group to a nitrogen atom on the spermidine molecule.


name: symbiont-mediated activation of host anti-inflammatory cytokine signaling

description: A process in which a symbiont subverts an anti-inflammatory cytokine signaling pathway in the host organism by initiating, promoting, or enhancing its activation.


wall teichoic acid catabolic process

description: The chemical reactions and pathways resulting in the breakdown of wall teichoic acid, which is a major component of the cell wall of Gram-positive bacteria and typically consists of a polymer of glycerol-phosphate or ribitol-phosphate to which are attached glycosyl and D-alanyl ester residues and which is covalently linked to peptidoglycan.


GMP catabolic process

description: The chemical reactions and pathways resulting in the breakdown of GMP, guanosine monophosphate.


CCC codon-amino acid adaptor activity

description: A triplet codon-amino acid adaptor activity that recognizes a CCC codon.


name: 4-hydroxyphenylacetate transmembrane transporter activity

description: Enables the transfer of 4-hydroxyphenylacetate from one side of a membrane to the other.


name: negative regulation of fibronectin-dependent thymocyte migration

description: Any process that stops, prevents or reduces the frequency, rate or extent of fibronectin-dependent thymocyte migration.


name: SA node cell to atrial cardiac muscle cell signaling

description: Any process that mediates the transfer of information from an SA node cardiomyocyte to an atrial cardiomyocyte.


name: regulation of response to cytokine stimulus

description: Any process that modulates the rate, frequency, or extent of a response to cytokine stimulus.


cell septum edging catabolic process

description: The chemical reactions and pathways resulting in the dissolution of the septum edging during cell separation.


description: Catalysis of the reaction: D-glucosamine + acetyl-CoA = N-acetyl-D-glucosamine + CoA + H+.


name: snoRNA transcription by RNA polymerase II

description: The synthesis of small nucleolar RNA (snoRNA) from a DNA template by RNA polymerase II, originating at an RNA polymerase II promoter.


peptidyl-lysine trimethylation

description: The methylation of peptidyl-lysine to form peptidyl-N6,N6,N6-trimethyl-L-lysine.


presynaptic membrane assembly

description: The aggregation, arrangement and bonding together of a set of components to form a presynaptic membrane, including any proteins associated with the membrane, but excluding other cellular components. A presynaptic membrane is a specialized area of membrane of the axon terminal that faces the plasma membrane of the neuron or muscle fiber with which the axon terminal establishes a synaptic junction.


name: ion channel modulating, G protein-coupled receptor signaling pathway

description: The series of molecular signals generated as a consequence of a G protein-coupled receptor binding to its physiological ligand, where the pathway proceeds through activation or inhibition of an ion channel.


acetyl-CoA biosynthetic process

description: The chemical reactions and pathways resulting in the formation of acetyl-CoA, a derivative of coenzyme A in which the sulfhydryl group is acetylated.


sequence-specific mRNA binding

description: Binding to messenger RNA (mRNA) of a specific nucleotide composition or a specific sequence motif.


interleukin-21 production

description: The appearance of interleukin-21 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


ether biosynthetic process

description: The chemical reactions and pathways resulting in the formation of ether.


name: positive regulation of distal tip cell migration

description: Any process that activates or increases the frequency, rate or extent of distal tip cell migration.


cytoplasmic translation

description: The chemical reactions and pathways resulting in the formation of a protein in the cytoplasm. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein.


positive regulation of DNA ligation

description: Any process that activates or increases the frequency, rate or extent of DNA ligation, the re-formation of a broken phosphodiester bond in the DNA backbone, carried out by DNA ligase.


CD86 biosynthetic process

description: The chemical reactions and pathways resulting in the formation of CD86, a CD marker that occurs on antigen presenting cells that provides co-stimulatory signals necessary for T cell activation and survival.


name: cell chemotaxis involved in Malpighian tubule morphogenesis

description: The directed movement of the outgrowing Malpighian tubule guided by specific chemical cues/signals. Movement may be towards a guidance cue (positive chemotaxis) or away from it (negative chemotaxis). Guidance contributes to the final positioning of the tubule.


neurofilament cytoskeleton organization

description: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising neurofilaments and their associated proteins.


description: Catalysis of the reaction: S-adenosyl-L-methionine + (protein)-arginine = S-adenosyl-L-homocysteine + (protein)-N-methyl-arginine.


name: regulation of atrial cardiac muscle cell action potential

description: Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in an atrial cardiac muscle cell contributing to the regulation of its contraction. This typically occurs via modulation of the activity or expression of voltage-gated ion channels.


name: positive regulation of posterior neural plate formation by fibroblast growth factor receptor signaling pathway

description: Any process that increases the rate or extent of the formation of the posterior neural plate, the posterior end of the flat, thickened layer of ectodermal cells known as the neural plate.


name: regulation of maltoheptaose metabolic process

description: Any process that modulates the frequency, rate or extent of maltoheptaose metabolic process.


name: 2-hydroxy-but-3-enyl glucosinolate biosynthetic process

description: The chemical reactions and pathways resulting in the formation of progoitrin, a 2-hydroxy-but-3-enyl glucosinolate. Glucosinolates are substituted thioglucosides found in rapeseed products and related cruciferae, and progoitrin has been implicated in causing goiters in mammals and bitter taste in cruciferous vegetables.


name: negative regulation of intracellular steroid hormone receptor signaling pathway

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of any intracellular steroid hormone receptor signaling pathway.


name: sequestering of BMP in extracellular matrix

description: Confining a bone morphogenetic protein (BMP) to the extracellular matrix (ECM), such that it is separated from other components of the signaling pathway, including its cell surface receptor. Bone morphogenetic proteins (BMPs) are secreted as homodimers, non-covalently associated with N-terminal pro-peptides, and are targeted to the extracellular matrix through interaction with matrix proteins.


rolling hairpin viral DNA replication

description: A viral DNA replication process where a 3' hairpin structure in the viral single-stranded DNA (ssDNA) template serves as a primer for host enzymes to synthesize DNA.


catabolism by virus of host DNA

description: The breakdown of host DNA, deoxyribonucleic acid, by a virus.


name: positive regulation of amine catabolic process

description: Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of amines.


p-cresol biosynthetic process

description: The chemical reactions and pathways resulting in the formation of p-cresol.


fructoselysine catabolic process

description: The chemical reactions and pathways resulting in the breakdown of fructoselysine.


siderophore catabolic process

description: The chemical reactions and pathways resulting in the breakdown of siderophores, low molecular weight Fe(III)-chelating substances made by aerobic or facultatively anaerobic bacteria, especially when growing under iron deficient conditions. The complexes of Fe(3+)-siderophores have very high stability constants and are taken up by specific transport systems by microorganisms; the subsequent release of iron requires enzymatic action.


name: regulation of erythrocyte apoptotic process

description: Any process that modulates the frequency, rate or extent of erythrocyte apoptotic process.


description: The appearance of vascular endothelial growth factor production due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


tRNA acetylation

description: The modification of tRNA structure by addition of an acetyl group to tRNA. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid.


fatty acid ligase activity

description: Catalysis of the ligation of a fatty acid to an acceptor, coupled to the hydrolysis of ATP.


protein targeting to Golgi apparatus

description: The process of targeting specific proteins to the Golgi apparatus. Usually requires an organelle-specific protein sequence motif or a protein modification (for example a palmitoylation).


name: programmed cell death involved in cell development

description: The activation of endogenous cellular processes that result in the death of a cell as part of its development.


name: positive regulation of mitotic cell cycle DNA replication

description: Any process that activates or increases the frequency, rate or extent of mitotic cell cycle DNA replication.


description: Catalyzes the reaction: UDP-alpha-D-xylose + [protein with EGF-like domain]-3-O-(beta-D-glucosyl)-L-serine = UDP + [protein with EGF-like domain]-3-O-(alpha-D-xylosyl-(1->3)-beta-D-glucosyl)-L-serine.


name: nuclear cell cycle DNA replication initiation

description: Any DNA replication initiation that is involved in nuclear cell cycle DNA replication.


integrin biosynthetic process

description: The chemical reactions and pathways resulting in the formation of integrins, a large family of transmembrane proteins that act as receptors for cell-adhesion molecules.


name: establishment of protein localization to vacuole

description: The directed movement of a protein to a specific location in a vacuole.


name: glucose catabolic process to D-lactate and ethanol

description: The anaerobic chemical reactions and pathways resulting in the enzymatic breakdown of D-glucose to D-lactate and ethanol, yielding energy in the form of adenosine triphosphate (ATP) at the rate of one ATP per glucose molecule.


name: vascular endothelial cell response to laminar fluid shear stress

description: Any response to laminar fluid shear stress in a vascular endothelial cell.


glyoxylate cycle

description: A modification of the TCA cycle occurring in some plants and microorganisms, in which isocitrate is cleaved to glyoxylate and succinate. Glyoxylate can then react with acetyl-CoA to form malate.


name: positive regulation of potassium ion export across plasma membrane

description: Any process that activates or increases the frequency, rate or extent of potassium ion export across the plasma membrane.


regulation of cellular component size

description: A process that modulates the size of a cellular component.


high-affinity IgE receptor activity

description: Combining with high affinity with an immunoglobulin of the IgE isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


eugenol biosynthetic process

description: The chemical reactions and pathways resulting in the formation of eugenol, a colorless, aromatic, liquid hydrocarbon (C10H12O2) found in clove oil.


name: 4,6-pyruvylated galactose residue biosynthetic process

description: The chemical reactions and pathways resulting in the formation of the pyruvylated galactose residue 4-6-O-[(R)(1-carboxyethylidine)]-Gal-beta-1,3-. The galactose residue is part of a larger polysaccharide chain.


regulation of gluconeogenesis

description: Any process that modulates the frequency, rate or extent of gluconeogenesis, the formation of glucose from noncarbohydrate precursors, such as pyruvate, amino acids and glycerol.


name: regulation of muscle cell apoptotic process

description: Any process that modulates the rate or frequency of muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a muscle cell and result in its death.


indole alkaloid metabolic process

description: The chemical reactions and pathways involving an indole alkaloid, an alkaloid containing an indole skeleton.


name: negative regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator

description: Any process that stops, prevents or reduces the frequency, rate or extent of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator.


prenyl-FMNH2 biosynthetic process

description: The chemical reactions and pathways resulting in prenyl-FMNH2, an essential cofactor for the decarboxylase enzymes UbiD and Fdc1.


name: nucleic acid transmembrane transporter activity

description: Enables the transfer of nucleic acids from one side of a membrane to the other. Nucleic acids are single or double-stranded polynucleotides involved in the storage, transmission and transfer of genetic information.


amino-acid betaine metabolic process

description: The chemical reactions and pathways involving any betaine, the N-trimethyl derivative of an amino acid.


name: negative regulation of corticotropin-releasing hormone receptor activity

description: Any process that stops, prevents or reduces the frequency, rate or extent of corticotropin-releasing hormone receptor activity.


name: rhamnogalacturonan I backbone metabolic process

description: The chemical reactions and pathways involving the alternating alpha-(1->2)-linked rhamnose and alpha-(1->2)-linked B-galacturonic acid residues of the rhamnogalacturonan I backbone.


L-leucine biosynthetic process

description: The chemical reactions and pathways resulting in the formation of L-leucine, 2-amino-4-methylpentanoic acid.


glucose catabolic process

description: The chemical reactions and pathways resulting in the breakdown of glucose, the aldohexose gluco-hexose.


cellular response to trehalose stimulus

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a trehalose stimulus.


CUC codon-amino acid adaptor activity

description: A triplet codon-amino acid adaptor activity that recognizes a CUC codon.


name: entry receptor-mediated virion attachment to host cell

description: The process by which a virion attaches to a host cell by binding to a receptor on the host cell surface that mediates/triggers viral entry by endocytosis/pinocytosis or by inducing fusion/penetration.


name: regulation of toll-like receptor 7 signaling pathway

description: Any process that modulates the frequency, rate, or extent of toll-like receptor 7 signaling pathway.


spindle assembly checkpoint signaling

description: A signaling process that delays the metaphase/anaphase transition until the spindle is correctly assembled and chromosomes are attached to the spindle.


RNA polyadenylation at postsynapse

description: A polyadenylation event (the enzymatic addition of a sequence of adenylyl residues at the 3' end of an RNA molecule) that takes place at a postsynapse.


positive regulation of immune response

description: Any process that activates or increases the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.


farnesol biosynthetic process

description: The chemical reactions and pathways resulting in the formation of the sesquiterpenoid alcohol farnesol, 3,7,11-trimethyl-2,6,10,dodecatrien-1-ol.


protein deneddylation

description: The removal of a ubiquitin-like protein of the NEDD8 type from a protein.


iron ion sequestering activity

description: Binding to an iron ion to prevent it from interacting with other partners or to inhibit its localization to the area of the cell or complex where it is active.


fruit dehiscence

description: The process leading to the spontaneous opening of the fruit permitting the escape of seeds.


tRNA dihydrouridine synthesis

description: The process whereby a uridine in a transfer RNA is converted to dihydrouridine.


dGTP diphosphatase activity

description: Catalysis of the reaction: dGTP + H2O = dGMP + H+ + diphosphate.


tRNA 2'-O-methyltransferase activity

description: Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing a 2'-O-nucleotide.


name: NAD-dependent histone deacetylase activity

description: Catalysis of the reaction: histone N6-acetyl-L-lysine + H2O = histone L-lysine + acetate. This reaction requires the presence of NAD, and represents the removal of an acetyl group from a histone.


molecular carrier activity

description: Directly binding to a specific ion or molecule and delivering it either to an acceptor molecule or to a specific location.


cephalosporin biosynthetic process

description: The chemical reactions and pathways resulting in the formation of a cephalosporin, any of large class of tetracyclic triterpene broad-spectrum antibiotics similar both chemically and in their mode of action to penicillin, first isolated from the culture filtrates of mediterranean fungus acremonium (cephalosporium acremonium), and effective against gram-positive bacteria.


name: modulation of voltage-gated sodium channel activity in another organism

description: Any process in which an organism effects a change in the frequency, rate or extent of the activity of a voltage-gated sodium channel in another organism.


name: cellular response to sugar-phosphate stress

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the accumulation of sugar-phosphate.


name: protein-L-isoaspartate (D-aspartate) O-methyltransferase activity

description: Catalysis of the reaction: S-adenosyl-L-methionine + protein L-beta-aspartate = S-adenosyl-L-homocysteine + protein L-beta-aspartate methyl ester.


[2Fe-2S] cluster assembly

description: The incorporation of two iron atoms and two sulfur atoms into an iron-sulfur cluster.


4-hydroxycoumarin metabolic process

description: The chemical reactions and pathways involving 4-hydroxycoumarin.


name: protein-phycocyanobilin linkage via S-phycocyanobilin-L-cysteine

description: The linkage of the chromophore phycocyanobilin to phycocyanin or allophycocyanin via S-phycocyanobilin-L-cysteine.


name: IRES-dependent translational initiation of circular RNA

description: The process where translation initiation recruits the 40S ribosomal subunits via an internal ribosome entry segment (IRES) before an AUG codon is encountered in an appropriate sequence context to initiate circular mRNA translation.


name: cellular response to zinc ion starvation

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of zinc ions.


name: symbiont-mediated perturbation of host programmed cell death

description: A process in which a symbiont gene product alters or subverts host programmed cell death, leading to a change in the frequency, rate or extent of host programmed cell death in the host cell. The host is defined as the larger of the organisms involved in a symbiotic interaction.


inflammatory response

description: The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages.


name: 5'-(N(7)-methyl 5'-triphosphoguanosine)-[mRNA] diphosphatase activity

description: Catalysis of the reaction: a 5'-end (N2,N2,N7-trimethyl 5'-triphosphoguanosine)-ribonucleoside in mRNA + H2O = a 5'-end diphospho-ribonucleoside in mRNA + 2 H+ + N7-methyl-GMP. Can also use (N7-methyl 5'-triphosphoguanosine)-ribonucleoside in mRNA as a substrate.


cellular response to vanadate(3-)

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vanadate(3-) stimulus.


phosphatidylcholine metabolic process

description: The chemical reactions and pathways involving phosphatidylcholines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline. They are important constituents of cell membranes.


leukotriene A4 metabolic process

description: The chemical reactions and pathways involving leukotriene A4.


geranyltranstransferase activity

description: Catalysis of the reaction: geranyl diphosphate + isopentenyl diphosphate = 2-trans,6-trans-farnesyl diphosphate + diphosphate.


name: monounsaturated fatty acid catabolic process

description: The chemical reactions and pathways resulting in the breakdown of monounsaturated fatty acid.


name: protein localization to actin cytoskeleton

description: A process in which a protein is transported to, or maintained in, the location of an actin cytoskeleton.


name: folic acid-containing compound metabolic process

description: The chemical reactions and pathways involving a folic acid-containing compound, i.e. any of a group of heterocyclic compounds based on the pteroic acid skeleton conjugated with one or more L-glutamic acid or L-glutamate units.


D-series resolvin biosynthetic process

description: The chemical reactions and pathways resulting in the formation of resolvin family D-series, hydroxy fatty acids derived from docosahexaenoic acid.


Fas signaling pathway

description: The series of molecular signals initiated by the binding of a ligand to a Fas receptor on the surface of the cell, and ending with the regulation of a downstream cellular process, e.g. transcription. Fas is a death domain-containing member of the tumor necrosis factor receptor (TNFR) superfamily.


protein localization to ascospore wall

description: A process in which a protein is transported to, or maintained in, a location within an ascospore wall.


response to brefeldin A

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a brefeldin A stimulus.


corrin biosynthetic process

description: The chemical reactions and pathways resulting in the formation of corrin, C19H22N4, the fundamental heterocyclic skeleton of the corrinoids. It consists of four reduced pyrrole rings joined into a macrocyclic ring. Corrin is the core of the vitamin B12 molecule.


fatty acid oxidation

description: The removal of one or more electrons from a fatty acid, with or without the concomitant removal of a proton or protons, by reaction with an electron-accepting substance, by addition of oxygen or by removal of hydrogen.


response to mercury ion

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mercury ion stimulus.


name: nuclear receptor-mediated glucocorticoid signaling pathway

description: A nuclear receptor-mediated signaling pathway initiated by a glucocorticoid binding to an intracellular receptor of the nuclear receptor protein family, and ending with regulation of a downstream cellular process, e.g. transcription.


description: The chemical reactions and pathways involving 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane (DDT), a chlorinated broad spectrum contact insecticide.


dipyrrin metabolic process

description: The chemical reactions and pathways involving dipyrrins (pyrromethanes), compounds containing two pyrrole rings linked through a methine, -CH=, group.


dGTP metabolic process

description: The chemical reactions and pathways involving dGTP, guanosine triphosphate.


cellular response to vitamin A

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin A stimulus.


leukotriene biosynthetic process

description: The chemical reactions and pathways resulting in the formation of leukotriene, a pharmacologically active substance derived from a polyunsaturated fatty acid, such as arachidonic acid.


name: response to spindle checkpoint signaling

description: A process that occurs in response to signals generated as a result of spindle checkpoint signaling.


vitamin D2 metabolic process

description: The chemical reactions and pathways involving vitamin D2, (3S,5Z,7E,22E)-9,10-secoergosta-5,7,10(19),22-tetraen-3-ol.


cytosolic valyl-tRNA aminoacylation

description: The process of coupling valine to valyl-tRNA in the cytosol, catalyzed by valyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.


name: neurotensin receptor activity, non-G protein-coupled

description: Combining with neurotensin, a neuropeptide active in the central and peripheral nervous system in mammals, and transmitting the signal from one side of the membrane to the other by a mechanism independent of coupling to G proteins.


name: regulation of mitochondrial membrane permeability involved in apoptotic process

description: Any regulation of mitochondrial membrane permeability that is involved in apoptotic process.


tubulin deacetylation

description: The removal of an acetyl group from tubulin. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid.


name: endocytosed synaptic vesicle to endosome fusion

description: Fusion of an endocytosed synaptic vesicle with an endosome.


maturation of SSU-rRNA

description: Any process involved in the maturation of a precursor Small SubUnit (SSU) ribosomal RNA (rRNA) molecule into a mature SSU-rRNA molecule.


RNA decapping

description: Cleavage of the 5'-cap of an RNA.