A member of the class of monomethoxyflavones that is 3'-methoxyflavone bearing an additional amino substituent at position 2'.


A sphingoid which is the 1-deoxymethylated derivative of 3-dehydrosphinganine.


motixafortide

A heterodetic cyclic peptide that has antineoplastic activity. It is a CXC chemokine receptor 4 (CXCR4) antagonist with an IC50 value of 0.8 nM and is currently under clinical investigation for the treatment of hematological malignancies, solid tumors, and stem cell mobilization. It was granted orphan drug designation by the FDA for the treatment of pancreatic cancer in 2019.


An eight-membered oligopeptide consisting of Asp, Tyr, Met, Gly, Trp, Met, As and Phe-NH2 residues joined in sequence.


sphingosine-based sphingolipid

A family of sphingolipids that share a common structural feature, a sphingosine base backbone.


An aminotetrasaccharide that is beta-D-Galp-(1->4)-beta-D-Galp-(1->3)-GalpNAc in which the non-terminal galatopyranosyl group has been glycosylated at position 2 by an alpha-L-fucopyranosyl group.


D-isoleucine derivative

A non-proteinogenic amino acid derivative resulting from reaction of D-isoleucine at the amino group or the carboxy group, or from the replacement of any hydrogen of D-isoleucine by a heteroatom.


A sialotetraosylceramide consisting of a branched octasaccharide made up from four sialyl residues, two galactose residues, one N-acetylglucosamine residue and a glucose residue at the reducing end attached to the ceramide portion via a beta-linkage.


A phytoceramide in which the ceramide N-acyl group is specified as tetradecanoyl (myristoyl).


name: 2-acetamido-4,5-dimethyl-3-thiophenecarboxylic acid [2-(2-chloro-5-methylsulfonylanilino)-2-oxoethyl] ester


The monoimine of 1,2-benzoquinone.


A triisocyanate being a derivative of isocyanuric acid with a 6-isocyanatohexyl group at each of the 1-, 3- and 5-positions.


An N-acyl-15-methylhexadecasphing-4-enine in which the acyl group has 18 carbons and 0 double bonds.


NITROETHANE

A nitroalkane that is ethane substituted by a nitro group.


name: 4-[butan-2-yl-[(3,4-dichloroanilino)-oxomethyl]amino]-1-piperidinecarboxylic acid ethyl ester


An aminotrisaccharide consisting of 2-acetamido-2-deoxy-alpha-D-galactose, beta-D-galactopyranose and 2-acetamido-2-deoxy-beta-D-glucopyranose residues joined in sequence by (1->3) and (1->4) glycosidic bonds.


zilucoplan

A 15 amino-acid, synthetic macrocyclic peptide with formula C172H278N24O55. Its sodium salt is used for the treatment of generalised myasthenia gravis (a disease that leads to muscle weakness and tiredness) in adults whose immune system produces antibodies against acetylcholine receptors.


An amino trisaccharide that is beta-D-GlcpNAc-(1->6)-alpha-D-Manp in which the acetamidoglucopyranosyl moiety has been glycosylated at position 3 by an alpha-L-fucopyranosyl group.


GlyTouCan G01883MR

A composition-only glycan consisting of seven hexosyl groups, five acetaminohexosyl groups and three N-acetyl-neuraminic acid groups (identities and connectivity unknown). Composition: Hex7 HexNAc5 NeuAc3.


L-tyrosinamide

An amino acid amide that is L-tyrosine in which the carboxy OH group is replaced by NH2.


Ac-Cha-Gpg-Disc-Nle-NMeBn

A synthetic tetrapeptide composed of the non-natural Ac-Cha, Gpg, Disc and Nle-NMeBn residues coupled in sequence.


N-methyl-N'-nitro-N-nitrosoguanidine

An N-nitroguanidine compound having nitroso and methyl substituents at the N'-position


L-alaninamide

An amino acid amide that is L-alanine in which the carboxy OH group is replaced by NH2.


ornithine derivative

A non-proteinogenic amino acid derivative resulting from reaction of ornithine at the amino group, the carboxy group, or the side-chain amino group, or from the replacement of any hydrogen of ornithine by a heteroatom. The definition normally excludes peptides containing ornithine residues.


Major species at pH 7.3.


glyoxamide

The simplest of the class of glyoxamides, with no substitution on nitrogen.


ketenimine

Imines where the C=N bond is conjugated to an alkylidene group.


N-methylputrescine

An N-monosubstituted putrescine where the N-substituent is methyl.


D-galactosyl-N-acylphytosphingosine

A glycosylceramide in which the glycosyl moiety is alpha-D-galactose and the ceramide is an N-acylphytosphingosine


CYCLOMONTANIN D

A homodetic cyclic peptide composed of L-alanyl, Lasparaginyl, L-prolylglycyl, L-leucyl, L-prolyl and L-tyrosyl residues linked in a sequence. It is isolated from the seeds of Annona montana and has been shown to exhibit anti-inflammatory activity.


N-acylhexadecasphinganine

A dihydroceramide consisting of an hexadecasphinganine base having an unspecified fatty acyl group attached to the nitrogen.


N-(1,2-saturated acyl)phytosphingosine

Any phytoceramide having a methylene group adjacent to the ceramide carbonyl group.


An amino trisaccharide consisting of beta-D-galactopyranose, 2-acetamido-2-deoxy-beta-D-glucoypranose and D-galactopyranose residues joined in sequence by (1->3) and (1->6) glycosidic bonds.


A ceramide that is the N-(2-hydroxyoctadecanoyl) derivative of 4-hydroxyeicosasphinganine.


2,3-dimethylphenyl isocyanate

An isocyanate that consists of phenyl isocyanate bearing two additional methyl substituents at positions 2 and 3.


A sphingoid obtained by formal oxidation of the 3-hydroxy group of hexadecasphinganine.


isophorone diisocyanate

A diisocyanate in which the two isocyanate groups are linked by an isophorone substituent.


A sphingolipid where the sphingoid base has 2 hydroxy groups and no double bonds, and the fatty acyl chain is hydroxylated at position C2. The chain lengths for both, the sphingoid base and the fatty acyl are undefined.


salicylaldehyde imine

Phenol with an iminomethyl substituent at the 2-position; the parent of the class of salicylaldehyde imines.


An amino tetrasaccharide that is 3-O-(2-acetamido-2-deoxy-beta-D-glucopyranosyl)-D-galactitol in which the hydroxy groups at positions 3 and 4 of the acetaminoglucopyranosyl moiety has been glycosylated by D-galactopyranosyl and L-fucosyl groups, respectively.


sialotriaosylceramide

A ganglioside in which the oligosaccharide portion is composed of a trisaccharide, to which one or more sialic acid residues are attached.


An eight-membered homodetic cyclic peptide comprising the sequence L-leucine, L-serine, L-alpha-glutamic acid, L-threonine, L-alpha-glutamic acid, L-threonine, N(6)-acetyl-L-lysine, D-leucine.


2-nitrophenyl beta-D-galactoside

A beta-D-galactoside having a 2-nitrophenyl substituent at the anomeric position.


A ceramide that is the N-eicosanoyl derivative of 4-hydroxyeicosasphinganine.


cysteine derivative

An amino acid derivative resulting from reaction of cysteine at the amino group, carboxy group, or thiol group, or from the replacement of any hydrogen of cysteine by a heteroatom. The definition normally excludes peptides containing cysteine residues.


Any 1-O-acyl-N-acylsphingosine in which the N-acyl group is specified as acetyl.


The cationic form of a C3 cyanine dye having 1,3-diethyl-5,6-dichloroindoleinine units at each end.


bis(azo) compound

Any  azo compound containing two -N=N- groups.


aci-nitroethane

An aci-nitro compound that is the predominant form of ethylnitronate at pH 7.3 (according to Marvin v 6.2.0.).


N-substituted cadaverine

An N-substituted diamine in which the diamine is cadaverine.


An N-acyl-1-O-beta-D-glucosyl-15-methylhexadecasphing-4-enine in which the acyl group has 18 carbons and 0 double bonds and is 2-hydroxylated.


A sialononaosylceramide having alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-[alpha-L-Fuc-(1->2)-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->6)]-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc as the sialononaosyl component.


An amino disaccharide consisting of a 2-acetamido-2-deoxy-beta-D-galactopyranose residue and a 2-acetamido-2-deoxy-D-galactopyranose residue joined in sequence by a (1->6) glycosidic bond.


An N-substituted ethylenediamine compound having 1-naphthyl as the substituent.


An amino trisaccharide that is D-mannopyranose in which the hydroxy groups at positions 2 and 3 have each been converted into the corresponding 2-acetamido-2-deoxy-beta-D-glucopyranosyl derivatives.


A phytoceramide having (2S,3R)-2,3-dihydroxytetracosanoyl as the N-acyl group.


A glycotriaosylceramide consisting of the trisaccharide alpha-L-fucosyl-(1->2)-beta-D-galactosyl-(1->4)-beta-D-glucose attached (via a glycosidic bond) to the primary hydroxy function of a ceramide with undefined sphingoid base.


amino acid amide

An amide of an amino acid formed formally by conversion of the carboxy group to a carboxamido group.


cerebroside

Any member of a group of glycosphingolipids, also known as monoglycosylceramides, which are important components in animal muscle and nerve cell membranes.


N-octacosanoylicosasphinganine

A C20 dihydroceramide in which the ceramide N-acyl group is specified as octacosanoyl.


ganglioside GP1c

An oligoglycosylceramide consisting of a branched nonasaccharide made up from five sialyl residues, two galactose residues, one N-acetylgalactosamine residue and a glucose residue at the reducing end attached to N-acylsphingosine via a beta-linkage.


L-asparagine derivative

A proteinogenic amino acid derivative resulting from reaction of L-asparagine at the amino group, the carboxy group, or the carboxamide, or from the replacement of any hydrogen of L-asparagine by a heteroatom.


beta-casomorphin-7 (human)

A seven amino acid oligopeptide fragment of the human milk protein, beta-casein. It is an inhibitor of pancreatic elastase, 5-HT2-serotonin receptors, mu-opioid receptors and delta-opioid receptors.


A sialopentaosylceramide consisting of a alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-beta-D-GalNAc-(1->4)-[alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)]-beta-D-Gal-(1->4)-beta-D-Glucosyl unit attached to the Cer(d18:1/22:0).


N-dodecanoylsphinganine

A dihydroceramide in which the ceramide N-acyl group is specified as dodecanoyl (lauroyl).


A N-acyl-(4E,14Z)-sphingadienine in which the N-acyl group is specified as octadecanoyl.


A phytoceramide in which the sphingoid component is specified as (4R,8Z)-4-hydroxysphing-8-enine.


N-acylamide

An acylamide having the general structure R(1)C(=O)NR(2)R(3) where one or both of R(2) and R(2) is an acyl group.


zorbamycin

A  glycopeptide antibiotic found in Streptomyces flavoviridis.


An N-acyl-1-O-beta-D-glucosyl-15-methylhexadecasphing-4-enine in which the acyl group has 23 carbons and 2 double bonds.


An alpha-NeuNAc-(2->3)-beta-D-Gal-(1->3)-beta-D-GalNAc-(1->4)-[alpha-NeuNAc-(2->3)]-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer in which the ceramide N-acyl group is specified as henicosanoyl.


An amino disaccharide consisting of an alpha-L-fucopyranose residue and a 2-acetamido-2-deoxy-alpha-D-glucopyranose residue joined in sequence by a (1->6) glycosidic bond.


An N-acyl-15-methylhexadecasphing-4-enine in which the acyl group has 21 carbons and 0 double bonds and is 2-hydroxylated.


An N-acyl-15-methylhexadecasphing-4-enine in which the acyl group has 27 carbons and 0 double bonds and is 2-hydroxylated.


A fifteen-membered glycopeptide comprising glycyl, cyclohexylglycyl, alanyl, glycyl, tyrosyl, (5R)-5-(beta-D-galactopyranosyloxy)lysyl, glycyl. alpha-glutamyl, glutaminyl, glycyl, prolyl, lysyl, glycyl, alpha-glutamyl and threonine residues coupled in sequence.


A glycotetraosylceramide having beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosyl component attached to the primary hydroxy function of a ceramide with undefined sphingoid base.


An N-acyl-1-O-beta-D-glucosyl-15-methylhexadecasphing-4-enine in which the acyl group has 24 carbons and 0 double bonds.


A ceramide obtained by formal condensation of the carboxy group of docosanoic acid with the amino group of 14-methylhexadecasphinganine. It is a metabolite of the nematode Caenorhabditis elegans.


quaternary nitrogen compound

A nitrogen molecular entity that is electronically neutral but which contains a quaternary nitrogen.


phosphenodiimidic amide

A phosphorus molecular entity that is phosphine in which the hydrogens are substituted by two imino groups and an amino group.


An amino trisaccharide consisting of two 2-acetamido-2-deoxy-beta-D-glucopyranose residues and a D-galactopyranose residue joined in sequence by (1->4) and (1->2) glycosidic linkages.


N-palmitoylhexadecasphinganine

An N-acylhexadecasphinganine in which the acyl group is specified as palmitoyl (hexadecanoyl).


A glycopentaosylceramide having N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl as the glycopentaosyl component.


primary phosphine

A compound derived from phosphane by substituting one hydrogen atom by a hydrocarbyl group.


PEPSTATIN

A pentapeptide isolated from Streptomyces testaceus. It is a potent inhibitor of aspartyl proteases.


name: carbamothioic acid S-[2-(2-methoxyanilino)-2-oxoethyl] ester


L-valine derivative

A proteinogenic amino acid derivative resulting from reaction of L-valine at the amino group or the carboxy group, or from the replacement of any hydrogen of L-valine by a heteroatom.


hemiaminal ether

An organic amino compound that is a hemiaminal in which the hydrogen atom of the hydroxy group has been replaced by an organyl group. General formula: R2C(OR')NR2 ( R =/= H ). Also known as alpha-amino ethers.


An amino disaccharide that is an N-acetyl-alpha-D-glucosamine in which the hydroxy group at position 3 has been converted into the corresponding beta-D-glucopyranoside.


Asn-Gly-Pro-His

A tetrapeptide composed of L-asparagine, glycine, L-proline, and L-histidine units joined in sequence by peptide linkages.


DICYCLOHEXYLCARBODIIMIDE

A carbodiimide compound having a cyclohexyl substituent on both nitrogen atoms.


An N-acyl-1-O-beta-D-glucosyl-15-methylhexadecasphing-4-enine in which the acyl group has 16 carbons and 0 double bonds and is 2-hydroxylated.


An amino tetrasaccharide that is 3-O-(2-acetamido-2-deoxy-alpha-D-glucopyranosyl)-D-galactopyranose in which the acetamidoglucosyl group has been glycosylated at positions 3 and 4 by beta-D-galactosyl and alpha-L-fucosyl groups, respectively.


An N-acyl-1-O-beta-D-glucosyl-15-methylhexadecasphing-4-enine in which the acyl group has 20 carbons and 0 double bonds and is 2-hydroxylated.


An amino trisaccharide that is D-galactopyranose in which the hydroxy groups at positions 3 and 4 have each been glycosylated by a 2-acetamido-2-deoxy-beta-D-glucopyranosyl group.


A sialotriaosylceramide consisting of the pentasaccharide N-acetyl-beta-D-galactosaminyl-(1->4)-[alpha-N-acetylneuraminyl-(2->8)-alpha-N-acetylneuraminyl-(2->3)]-beta-D-galactosyl-(1->4)-beta-D-glucose attached to the primary hydroxy function of a ceramide with an undefined sphingoid base.


A tetrapeptide comprising N(2)-acetyl-D-phenylalanine, beta-alanine, L-histidine and D-prolinamide residues coupled in sequence.


Glu-Leu-Phe-Ala

A tetrapeptide composed of L-glutamic acid, L-leucine, L-phenylalanine and L-alanine joined in sequence by peptide linkages.


name: 2-[[(2-chlorophenyl)-oxomethyl]amino]acetic acid [2-(2-chloroanilino)-2-oxoethyl] ester


A beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-N-acylsphinganine in which the acyl group specified is hexadecanoyl.


A hexosyl-(1<->1')-N-acylsphinganine in which the hexosyl component is specified as beta-D-galactosyl.


SANGIVAMYCIN

A nucleoside analogue that is adenosine in which the nitrogen at position 7 is replaced by a carbamoyl-substituted carbon. It is a potent inhibitor of protein kinase C.


An N-acyl-1-O-beta-D-glucosyl-15-methylhexadecasphing-4-enine in which the acyl group has 19 carbons and 1 double bond.


diphenhydramine salicylate

The salicylic acid salt of diphenhydramine.


monoglyoxamide

A compound containing a single glyoxamide unit.


cyclopropylcarboxamide

Carboxamides RC(=O)NR'R'' where R is a cyclopropyl group.


A beta-alanine derivative obtained by formal condensation of the carboxy group of orotic acid with the amino group of methyl beta-alaninate. One of a series of mucosal-associated invariant T (MAIT) cell agonists.


quinone imine

An imine formed formally from a quinone by replacement of one or more atoms of quinonoid oxygen by =NH or =NR.


A tetrapeptide composed of L-phenylalanine, glycine, L-leucine, and L-methioninamide joined in sequence by peptide linkages. It is a C-terminal fragment of substance P.


(Z)-2-methylpropanal oxime

A 2-methylpropanal oxime in which the oxime double bond has Z geometry.


dual action dynamin inhibitor


primary nitroalkane

A nitroalkane in which the nitro group is attached to a terminal carbon. Major microspecies at pH 7.3.


A glycopentaosylceramide having alpha-L-fucosyl-(1->2)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl component attached to the primary hydroxy function of a ceramide with undefined sphingoid base.


An amino disaccharide consisting of an alpha-D-glucopyranose residue and a 2-acetamido-2-deoxy-alpha-D-allopyranose residue joined in sequence by a (1->4) glycosidic bond.


name: ganglioside GM2 (18:0) (NeuAc-N-deacetyl)

description: A sialotriaosylceramide that is ganglioside GM2 (18:0) in which the sialo N-acetyl group has been deacetylated.


diisocyanate

An isocyanate compound containing two isocyanate functional groups. Manufactured for reaction with polyols in the production of polyurethanes.


A phytoceramide in which the ceramide N-acyl group is specified as 2-hydroxyhexadecanoyl


An N-acyl-1-O-beta-D-glucosyl-15-methylhexadecasphing-4-enine in which the acyl group has 26 carbons and 2 double bonds.


A glycotriaosylceramide having alpha-D-galactosyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosyl as the glycotriaosyl component attached to the Cer(d18:1/22:0).


threonine derivative

An amino acid derivative resulting from reaction of threonine at the amino group or the carboxy group, or from the replacement of any hydrogen of threonine by a heteroatom. The definition normally excludes peptides containing threonine residues.


biuret

A member of the class of condensed ureas that is the compound formed by the condensation of two molecules of urea; the parent compound of the biuret group of compounds. Used as a non-protein nitrogen source in ruminant feed.


An alpha-D-GlcpNAc-(1->4)-D-GlcpNAc in which the carbon bearing the anomeric hydroxy group has beta configuration.


A sialopentaosylceramide consisting of a alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-beta-D-GalNAc-(1->4)-[alpha-Neu5Ac-(2->3)]-beta-D-Gal-(1->4)-beta-D-Glucosyl unit attached to a Cer(d18:1/24:2), the position of the double bond in the tetracosadienoyl group being unspecified. .


GlyTouCan G02791WJ

A composition-only glycan consisting of six hexosyl groups, six acetaminohexosyl groups, two 6-deoxyhexosyl groups and three N-acetyl-neuraminic acid groups (identities and connectivity unknown). Composition: Hex6 HexNAc6 dHex2 NeuAc3.


A fifteen-membered glycopeptide comprising glycyl, glutaminyl, alanyl, glycyl, tyrosyl, (5R)-5-(beta-D-galactopyranosyloxy)lysyl, glycyl. alpha-glutamyl, glutaminyl, glycyl, prolyl, lysyl, glycyl, alpha-glutamyl and threonine residues coupled in sequence.


A beta-D-glucosyl-(1<->1')-N-acylsphinganine in which the acyl group specified is hexacosanoyl.


KETOROLAC TROMETHAMINE

An organoammonium salt resulting from the mixture of equimolar amounts of ketorolac and tromethamine (tris). It has potent non-sedating analgesic and moderate anti-inflammatory effects. It is used in the short-term management of post-operative pain, and in eye drops to relieve the ocular itching associated with seasonal allergic conjunctivitis.


An amino disaccharide consisting of alpha-L-fucopyranose and 2-acetamido-2-deoxy-alpha-D-glucopyranose residues joined in sequence by a (1->4) glycosidic bond.


N-docosanoylsphinganine

A dihydroceramide in which the ceramide N-acyl group is specified as docosanoyl (behenoyl).


name: L-Proline, N-propargyloxycarbonyl-, propargyl ester


ARGIPRESTOCIN

A heterodetic cyclic peptide that is homologous to oxytocin and vasopressin. It is a pituitary hormone that acts as an endocrine regulator for water balance, osmotic homoeostasis and is involved in social and sexual behavior in non-mammalian vertebrates.


An N-acyl-15-methylhexadecasphing-4-enine in which the acyl group has 26 carbons and 1 double bond. It is a metabolite of the nematode Caenorhabditis elegans.


A glycophytoceramide having a 4-O-[3-(4-tert-butylphenyl)propyl]-alpha-D-galactosyl residue at the O-1 position and a hexacosanoyl group attached to the nitrogen. One of a series of an extensive set of 4"-O-alkylated alpha-GalCer analogues evaluated (PMID:30556652) as invariant natural killer T-cell (iNKT) antigens.


A C20 dihydroceramide in which the ceramide N-acyl group is specified as 2-hydroxyoctacosanoyl.


Phenol substituted with nitro groups at both ortho-positions and at the meta-position.


methyl isocyanate

The isocyanate that is methane modified by a single isocyanato substituent.


An amino disaccharide consisting of 2-acetamido-2-deoxy-alpha-D-glucopyranose and beta-D-glucopyranose residues joined in sequence by a (1->2) glycosidic linkage.


ceruletide

A decapeptide comprising 5-oxoprolyl, glutamyl, aspartyl, O-sulfotyrosyl, threonyl, glycyl, tryptopyl, methionyl, aspartyl and phenylalaninamide residues in sequence. Found in the skins of certain Australian amphibians, it is an analogue of the gastrointestinal peptide hormone cholecystokinin and stimulates gastric, biliary, and pancreatic secretion. It is used in cases of paralysis of the intestine (paralytic ileus) and as a diagnostic aid in pancreatic malfunction.


A sialotetraosylceramide having alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-beta-D-GalNAc-(1->4)-beta-D-Gal-(1->4)-beta-D-Glc as the sialotetraosyl component.


triphenylphosphine

A member of the class of  tertiary phosphines that is phosphane in which the three hydrogens are replaced by phenyl groups.


oritavancin

A semisynthetic glycopeptide used (as its bisphosphate salt) for the treatment of acute bacterial skin and skin structure infections caused or suspected to be caused by susceptible isolates of designated Gram-positive microorganisms including MRSA.


name: N-[[4-oxo-4-(2,4,6-trimethylanilino)butan-2-ylidene]amino]carbamic acid tert-butyl ester


monoamine

An aralylamino compound which contains one amino group connected to an aromatic ring by a two-carbon chain. Monoamines are derived from aromatic amino acids like phenylalanine, tyrosine, tryptophan, and the thyroid hormones by the action of aromatic amino acid decarboxylase enzymes.


D-isoglutamine

An isoglutamine that has D-configuration.


A 12 amino acid oligopeptide fragment of apelin-13 lacking the terminal L-phenylalanine residue.


A glycotriaosylceramide having N-acetyl-beta-D-galacto-hexodialdo-1,5-pyranosaminyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosyl as the triaosyl component.


A ceramide that is the N-(2-hydroxydocosanoyl) derivative of 4-hydroxyeicosasphinganine.


An amino trisaccharide consisting of alpha-L-fucopyranose, 2-O-methyl-beta-D-galactopyranose and 2-acetamido-2-deoxy-beta-D-glucopyranose residues joined in sequence by (1->3) and (1->4) glycosidic bonds.


Leu-Ser-Glu-Thr-Glu-Thr-Leu

A seven-membered oligopeptide comprising L-leucine, L-serine, L-glutamic acid, L-threonine, L-glutamic acid, L-threonine and L-leucine residues coupled in sequence.


A sialotriaosylceramide consisting of the tetrasaccharide N-acetyl-beta-D-galactosaminyl-(1->4)-[alpha-N-acetylneuraminyl-(2->3)]-beta-D-galactosyl-(1->4)-beta-D-glucose attached to the primary hydroxy function of a ceramide with an undefined sphingoid base.


A glycosphingolipid that is N-acetyl-beta-D-galactosaminyl-(1->4)-alpha-N-acetylneuraminosyl-(2->3)-beta-D-galactosyl-(1->4)-beta-D-glucose linked (1<->1') to sphingosine [(2S,3R,4E)-2-aminooctadec-4-ene-1,3-diol].  A synthetic modification of the natural ganglioside GM2.


A beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-N-acylsphingosine in which the acyl group specified is docosanoyl.


4-nitrophenyl alpha-D-xyloside

A xyloside that is alpha-D-xylopyranose in which the anomeric hydroxy hydrogen is replaced by a 4-nitrophenyl group.


galactosylceramide 42:2

A galactosylceramide in which the acyl group and the sphingoid base contain a total of 42 carbon atoms and 2 double bonds.


A sialotriaosylceramide consisting of a linear pentasaccharide made up from two N-acetylneuraminyl residues, an N-acetyl-beta-D-glucosaminyl residue, a mannosyl residue and a glucosyl residue at the reducing end attached to the ceramide portion via a beta-linkage.


A C5-cyanine dye having differentially-substituted 2-indolyl units at each end.


BISTRATAMIDE H

A homodetic cyclic peptide that consists of L-valine as the amino acid residue. It is isolated from Lissoclinum bistratum and exhibits antitumour activity against the human colon tumour cell line.


methylguanidine

A guanidine in which one of the amino hydrogens of guanidine itself is substituted by a methyl group.


L-Ala-gamma-D-Glu-meso-Dap-D-Ala

A tetrapeptide comprising L-alanyl, gamma-D-glutamyl, meso-diaminopimelyl and L-alanine units in a linear sequence.


nitrosamine

N-Nitroso amines, compounds of the structure R2NNO. Compounds RNHNO are not ordinarily isolable, but they, too, are nitrosamines. The name is a contraction of N-nitrosoamine and, as such, does not require the N locant.


Cys-Met-Met-Met

A tetrapeptide composed of one L-cysteine and three L-methionine units joined by peptide linkages.


N-(hexadecanoyl)eicosasphinganine

A ceramide that is the N-palmitoyl (hexadecanoyl) derivative of eicosasphinganine.


An N-acyl-1-O-beta-D-glucosyl-15-methylhexadecasphing-4-enine in which the acyl group has 20 carbons and 1 double bond.


benzanilide fungicide

Any anilide fungicide whose structure contains a benzanilide group [ArC(=O)N(R)Ar', where Ar and Ar' are phenyl or substituted phenyl groups].


chlormerodrin ((197)Hg)

Chlormerodrin containing the radioactive isotope (197)Hg. It was formerly used as a diagnostic aid in determination of renal function.


A carbodiimide compound having a 4-methylphenyl substituent on both nitrogen atoms.


2-dimethylaminoethylphosphonic acid

A phosphonic acid having a 2-dimethylaminoethyl group attached to the phosphorus.


An N-acetyl-beta-D-glycosaminyl glycopeptide consisting of an N-acetyl-beta-D-glycosaminyl-(1->4)-N-acetylmuramoyl moiety attached to the amino terminus of the tetrapeptide L-alanyl-D-glutamyl-6-carboxy-L-lysyl-D-alanine via an amide linkage.


A sialotetraosylceramide having alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-[alpha-Neu5Ac-(2->6)]-beta-D-GalNAc-(1->4)-beta-D-Gal-(1->4)-beta-D-Glc as the sialotetraosyl component.


A 1-O-acyl-N-acylsphingosine in which the N- and O-acyl groups are specified as acetyl and stearoyl (octadecanoyl) respectively.


An L-tryptophan derivative in which the indolyl ring nitrogen carries a nitroso substituent.


DPDPE

A heterodetic cyclic peptide that is a cyclic enkephalin analogue, having D-penicillaminyl residues located at positions 2 and 5, which form the heterocycle via a disulfide bond.


mature microcin B18 zwitterion

The current microcin B17, CHEBI:64624 is a precursor, see fig. 2


Asp-Trp-Trp-Val

A tetrapeptide composed of L-aspartic acid, two L-tryptophan units and L-valine joined in sequence by peptide linkages.


Ala-Leu-Leu-Asp

A tetrapeptide composed of L-alanine, two L-leucine units, and L-aspartic acid joined in sequence by peptide linkages.


name: chondroitin sulfate E (GalNAc4,6diS-GlcA), precursor 5a


A mononitrotoluene that consists of toluene bearing a nitro substituent at the 4-position.


amidoxime

Amidines of general formula RC(=NOH)NR(1)R(2), in which the imino nitrogen is substituted by a hydroxy group.


chlormerodrin

Urea in which one of the hydrogens is substituted by a 3-chloromercury-2-methoxyprop-1-yl group. It was formerly used as a diuretic, but more potent and less toxic drugs are now available. Its radiolabelled ((197)Hg, (203)Hg) forms were used in diagnostic aids in renal imaging and brain scans.


An N-acyl-D-galactosylsphingosine in which the ceramide N-acyl group is composed of 24 carbons, 2 double bonds and a hydroxyl at C2.


N-sulfonylcarboxamide

A mixed diacylamine resulting from the formal condensation of the nitrogen of a carboxamide with a sulphonic acid.


N-benzylacetamides

Amides based on a skeleton with the general formula RNHC(=O)CH3 where R is a benzyl or substituted-benzyl group.


An amino trisaccharide that is 2-acetamido-2-deoxy-beta-D-glucopyranose in which the hydroxy groups at positions 4 and 6 have been converted into the corresponding 2-acetamido-2-deoxy-beta-D-glucopyranosyl and alpha-L-fucopyranosyl derivatives, respectively.


N-acetylcysteamine

A member of the class of  acetamides that is the N-acetyl-deriavtive of cysteamine.


An amino disaccharide consisting of 2-acetamido-2-deoxy-alpha-D-glucopyranose and beta-D-mannopyranose residues joined in sequence by a (1->4) glycosidic bond.


biocytinamide

An  amino acid amide formed by amidation of the carboxy function of biocytin: a fluorogenic reagent for specific C-terminal labelling of peptides and proteins by carboxypeptidase Y catalyzed transpeptidation reactions.


A C-nitro compound consisting of uracil having a nitro group at the 5-position.


A glycosyl alditol derivative that is N-acetyl-D-galactosaminitol in which the hydroxy group at position 3 has been glycosylated by an alpha-D-galactopyranosyl group.


neurotensin (1-8)

An 8 amino acid peptide fragment of neurotensin.


GLYCINEXYLIDIDE

A amino acid amide with 2,6-dimethylaniline and glycine components; an active metabolite of lidocaine, formed by oxidative deethylation. Used as an indicator of hepatic function.


An N-acyl-15-methylhexadecasphing-4-enine in which the acyl group has 25 carbons and 0 double bonds and is 2-hydroxylated.


A mononitrotoluene that is toluene carrying a nitro substituent at position 2.


An N-glycosylated glycine in which the saccharide component is the branched nonasaccharide alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc


A glycopentaosylceramide having beta-D-GlcA-(1->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc as the pentasaccharide component; isolated from human sciatic nerves and cauda equina.


name: 2-[[cyclohexyl(oxo)methyl]amino]acetic acid [2-(2-chloroanilino)-2-oxoethyl] ester


N-stearoylhexadecasphinganine

An N-acylhexadecasphinganine in which the acyl group is specified as stearoyl (octadecanoyl).


An amino disaccharide consisting of 2-acetamido-2-deoxy-beta-D-glucopyranose and beta-D-mannopyranose joined in sequence by a (1->2) glycosidic bond.


N-NITROSODIETHYLAMINE

A nitrosamine that is N-ethylethanamine substituted by a nitroso group at the N-atom.


phalloidin

A homodetic bicyclic heptapeptide having a sulfide bridge.


A beta-D-glucosylceramide in which a beta-D-glucosyl residue attached to the primary hydroxyl group of N-tetracosanoyl-14-methylhexadecasphingosine. It is a metabolite of the nematode Caenorhabditis elegans.


GD1a-GD1a dimer

A ganglioside derivative derived from two GD1a skeletons linked through their amino nitrogen atoms by an adipoyl (hexanedioyl) group.


A glycophytoceramide having an alpha-D-galactopyranosyl residue at the O-1 position and a 6-([1,1'-biphenyl]-4-yl)hexanoyl group attached to the nitrogen.


TYROCIDINE C

A homodetic cyclic decapeptide consisting of D-Phe, L-Pro, L-Trp, D-Trp, L-Asn, L-Gln, L-Tyr, L-Val, L-Orn, and L-Leu residues coupled in sequence and cyclised head-to-tail.


An amino disaccharide consisting of 2-acetamido-2-deoxy-alpha-D-glucopyranose and 2-acetamido-2-deoxy-D-glucopyranose residues joined in sequence by a (1->3) glycosidic bond.


A glycophytoceramide having an alpha-D-galactopyranosyl residue at the O-1 position and a 10-phenyldecanoyl group attached to the nitrogen.


sialononaosylceramide

A ganglioside in which the oligosaccharide portion is composed of a nonasaccharide, to which one or more sialic acid residues are attached.


L-cysteine derivative

A proteinogenic amino acid derivative resulting from the formal reaction of L-cysteine at the amino group, carboxy group, or thiol group, or from the replacement of any hydrogen of L-cysteine by a heteroatom.


N-ethylacetamide

A member of the class of acetamides that is the N-ethyl derivative of acetamide.


A ceramide in which the acyl group and the sphingoid base contain a total of 42 carbon atoms and 1 double bond.


5-acetamidopentanoic acid

A member of the class of  acetamides that is the acetyl derivative of 5-aminopentanoic acid.


A glycophytoceramide having a 6-thio-alpha-D-galactopyranosyl residue at the O-1 position and a hexacosanoyl group attached to the nitrogen.


cyclohexyl isocyanate

An isocyanate comprising a cyclohexane core with a single isocyanato substituent.


An amino disaccharide that is the 3-O-beta-D-galactopyranoside of 2-acetamido-2-deoxy-D-glucitol.


A glycophytoceramide having an alpha-D-galactopyranosyl residue at the O-1 position and an 11-([1,1'-biphenyl]-4-yl)undecanoyl group attached to the nitrogen.


nitrate ester

Any member of the class of nitrates resulting from the esterification of nitric acid with an alcohol.


An oligopeptide composed of L-alanine, L-arginine, glycine, L-tyrosine, L-serine, L-serine, L-phenylalanine, L-isoleucine, L-tyrosine, L-trytophan, L-phenylalanine and L-phenylalanine joined in sequence by peptide linkages.


C16 phytosphingosine

A sphingoid that is C16 sphinganine bearing an additional 4R-hydroxy substituent.


name: GIPC-anchor amidated L-alanine residue(1-)

description: A GIPC-anchor amidated amino acid where R1 represents the shingoid base, R2 is an acyl group, R3 can be an acyl group or an H, R4-8 can be other sugar groups, phosphoethanolamine or H.


An N-acyl-1-O-beta-D-glucosyl-15-methylhexadecasphing-4-enine in which the acyl group has 16 carbons and 0 double bonds.


N-acylhexadecasphingosine

A ceramide consisting of an hexadecasphing-4-enine base having an unspecified fatty acyl group attached to the nitrogen.


hydrazonamide

Any organonitrogen compound derived from carboxamides, RC(=O)NR2, by formal condensation with hydrazine (or a substituted hydrazine) to replace the double-bonded oxygen atom by =NNR2 to give RC(=NNR2)NR2.


An N-acyl-1-O-beta-D-glucosyl-15-methylhexadecasphing-4-enine in which the acyl group has 25 carbons and 1 double bond.


A D-galactosyl-N-acylsphingosine in which the fatty acyl group contains 18 carbons and 1 double bond.


An alpha-galactosylceramide in which the nitrogen carries a hexacosanamido group and C-4 carries in addition to a hydroxy function a 2-phenylethyl group. Essentially a phytosphingosine analogue with a truncated lipid chain terminating in a benzene ring, it has been used in investigations on the binding affinity of glycolipids to CD1d molecules.


name: 5-amino-4-[anilino(oxo)methyl]-3-methyl-2-thiophenecarboxylic acid ethyl ester


phenylhydrazines

Any member of the class of  hydrazines carrying a phenyl substituent.


A quinone imine that is 1,4-benzoquinone imine substituted by a methoxy group at position 3 and a (phenylacetyl)nitrilo group attached to the nitrogen atom. Isolated from the fermentation broth of Penicillium minioluteum, it exhibits neurotrophic effect of NGF.


An amino disaccharide comprised of 2-acetamido-beta-D-glucopyranose linked (1->4) to beta-D-mannopyranose.


A sialohexaosylceramide consisting of a branched heptasaccharide made up from one sialyl residue, two galactose residues, three N-acetylglucosamine residues and a glucose residue at the reducing end attached to the ceramide portion via a beta-linkage.


A beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-N-acylsphingosine in which the acyl group specified is tetracosanoyl.


L-erythro-N-acylsphingosine

A sphingolipid comprising an unspecified fatty acyl group attached to the nitrogen of L-erythro-sphingosine.


A glycosyl alditol derivative consisting of two alpha-D-mannopyranose residues and 2-acetamido-2-deoxy-D-glucitol joined in sequence by (1->2) and (1->3) glycosidic bonds.


GlyTouCan G01797UE

A composition-only glycan consisting of seven hexosyl groups, six acetaminohexosyl groups, one 6-deoxyhexosyl group, three N-acetyl-neuraminic acid groups and one N-glycolyl-neuraminic acid group (identities and connectivity unknown). Composition: Hex7 HexNAc6 dHex1 NeuAc3 NeuGc1.


N-acylimine

An acylimine having the general structure R'N=CR2 where R' is an acyl group.


A sialotetraosylceramide consisting of a branched decasaccharide made up from six sialyl residues, two galactose residues, one N-acetylglucosamine residue and a glucose residue at the reducing end attached to the ceramide portion via a beta-linkage.


ethylammonium acetate

An organoammonium salt resulting from the mixing of equimolar amounts of acetic acid and ethylamine.


[Met]enkephalin

A peptide zwitterion obtained by transfer of a proton from the carboxy to the amino terminus of Met-enkephalin. Major species at pH 7.3.


N-lignoceroyl-D-galactosylsphingosine

An N-acyl-D-galactosylsphingosine in which the ceramide N-acyl group is specified as lignoceroyl (tetracosanoyl).


ADA

A nitrogen molecular entity with role as Good's buffer.


TRICIRIBINE

A nucleoside analogue in which the nucleobase portion is a 1,4,5,6,8-pentaazaacenaphthylene ring system substituted with an amino group at position 3, and a methyl group at position 5 and is bound to the beta-D-ribofuranosyl moiety by an N(1)-glycosidic linkage.


name: 1-[4-[[oxo-(7-oxo-4H-isothiazolo[4,3-d]pyrimidin-3-yl)methyl]amino]phenyl]-3-piperidinecarboxylic acid ethyl ester


GlyTouCan G41247ZX

A partially-defined glycan consisting of 6 hexosyl and 2 acetaminohexosyl groups (identities and connectivity unknown). Composition: Hex6 HexNAc2.


triptorelin

An oligopeptide comprising pyroglutamyl, histidyl, tryptophyl, seryl, tyrosyl, D-tryptophyl, leucyl, arginyl, prolyl and glycinamide residues joined in sequence. It is an agonist analogue of gonadotropin-releasing hormone.


An amino trisaccharide consisting of alpha-D-galactopyranosyl, 2-acetamido-2-deoxy-beta-D-glucopyranosyl and D-mannopyranose residues joined in sequence by (1->3) and (1->2) glycosidic bonds.


A synthetic six-membered oligopeptide composed of the non-natural Ac-Cha, Gpg, Disc, Nle, betaPhPro and [S(oxaz)L]-NMe2 residues coupled in sequence.


BISTRATAMIDE G

A homodetic cyclic peptide that consists of L-valine as the amino acid residue. It is isolated from Lissoclinum bistratum and exhibits antitumour activity against the human colon tumour cell line.


A N-(2-hydroxyacyl)-beta-D-galactosylsphinganine in which the ceramide N-acyl group is specified as 2-hydroxyhexanoyl.


An amino disaccharide that is 2-acetamido-2-deoxy-alpha-D-galactopyranose in which the hydroxy group at position 3 has been converted into the corresponding beta-D-glucopyranoside.


PHENYLALANINE AMIDE

An amino acid amide derived from L-phenylalanine.


cis-azoxybenzene

An azoxybenzene with a cis-configuration.


Z-DEVD-FMK

A tetrapeptide consisting of Fmoc-L-aspartic acid 4-methyl ester, methyl L-alpha-glutamic acid 5-methyl ester, L-valine and the fluoromethyl ketone derived from the 1-carboxy group of L-aspartic acid 4-methyl ester coupled in sequence. It is a specific, irreversible caspase-3 inhibitor that also shows potent inhibition of caspase-6, caspase-7, caspase-8, and caspase-10.


A nucleoside analogue having 6-methyl-3,5-dihydro-9H-imidazo[1,2-a]purin-9-one as the modified nucleobase.


An N-acyl-1-O-beta-D-glucosyl-15-methylhexadecasphing-4-enine in which the acyl group has 18 carbons and 4 double bonds and is 2-hydroxylated.


A glycine derivative that is glycinamide in which one of the amino hydrogens is replaced by a 9-beta-D-ribofuranosylpurin-6-yl group.


A  C-nitro compound that is phenylhydrazine substituted at the 2- and 4-positions by nitro groups.


N-hydroxyarylamine

Any hydroxylamine where the nitrogen is attached directly to an aryl group.


An N-acylsphinganine in which the fatty acyl group contains 18 carbons and 1 double bond.


ganglioside GM2 (5:0)

A sialotriaosylceramide that is N-acetyl-beta-D-galactosaminyl-(1->4)-alpha-N-acetylneuraminosyl-(2->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-N-acylsphingosine in which the acyl group on the sphingosine nitrogen is pentanoyl. A synthetic modification of the natural ganglioside GM2.


A diisocyanate consisting of diphenylmethane with two isocyanate groups at the 4- and 4'-positions.


An amino tetrasaccharide consisting of a 2-acetamido-2-deoxy-beta-D-glucopyranose residue, two beta-D-mannopyranose residues and a beta-D-glucopyranose residue joined in sequence by (1->2), (1->2), and (1->4) glycosidic bonds.


The cationic form of BoBo-3, a symmetrical cyanine dye.


N-carbamoyl-L-cysteine

A cysteine derivative that is the N-carbamoyl derivative of L-cysteine.


A glycooctaosylceramide having an beta-D-Gal-(1->4)-[alpha-L-Fuc-(1->3)]-beta-D-GlcNAc-(1->6)-[beta-D-Gal-(1->3)]-beta-D-GalNAc-(1->3)-alpha-D-Gal-(1->4)-beta-D-Gal-(1->4)--D-Glcp component attached to the primary hydroxy function of a ceramide with a d18:1 sphingoid base and an undefined fatty acyl chain.


A N-acyl-beta-D-galactosylsphingosine in which the acyl group is (15Z)-tetracosenoyl.


ethyl isocyanate

An isocyanate having an ethyl group attached to the nitrogen.


aminoguanidine

A one-carbon compound whose unique structure renders it capable of acting as a derivative of hydrazine, guanidine or formamide.


2-ureidoglycine zwitterion

The zwitterion resulting from the transfer of a proton from the carboxy group to the alpha-amino group of 2-ureidoglycine.


Any ceramide in which the acyl group carries a hydroxy substituent at position 2.


A tetrapeptide comprising N(2)-acetyl-L-glutamine, D-phenylalanine, L-histidine and D-prolinamide residues coupled in sequence.


vitamin B3

Any member of a group of vitamers that belong to the chemical structural class called pyridines that exhibit biological activity against vitamin B3 deficiency. Vitamin B3 deficiency causes a condition known as pellagra whose symptoms include depression, dermatitis and diarrhea. The vitamers include nicotinic acid and nicotinamide (and their ionized and salt forms).


Cys-Cys-His-His

A tetrapeptide composed of two L-cysteine units joined to two  L-histidine units by a peptide linkage.


4-nitrophenyl beta-D-xyloside

A xyloside that is beta-D-xylopyranose in which the anomeric hydroxy hydrogen is replaced by a 4-nitrophenyl group.


A sialotriaosylceramide consisting of  beta-D-GalNAc-(1->4)-[alpha-Neu5Ac-(2->3)]-beta-D-Gal-(1->4)-beta-D-Glc attached to the primary hydroxy function of ceramide(d18:1/16:0).


An amino disaccharide consisting of 2-acetamido-2-deoxy-beta-D-galactopyranose and beta-D-glucopyranose residues joined in sequence by a (1->4) glycosidic bond.


name: acetic acid [2-[2-(2-acetyloxy-5-methoxy-3-nitrophenyl)ethenyl]-4-quinolinyl] ester


An N-acyl-1-O-beta-D-glucosyl-15-methylhexadecasphing-4-enine in which the acyl group has 16 carbons and 1 double bond.


A fifteen-membered glycopeptide comprising glycyl, 3-(1,3-thiazol-4-yl)alanyl, alanyl, glycyl, 3-methylphenylalanyl, (5R)-5-(beta-D-galactopyranosyloxy)lysyl, glycyl. alpha-glutamyl, glutaminyl, glycyl, prolyl, lysyl, glycyl, alpha-glutamyl and threonine residues coupled in sequence.


An L-tryptophan derivative that is L-tryptophan with a methoxy substituent at position 5.


name: butanoic acid [2-oxo-2-(4-phenyldiazenylanilino)ethyl] ester


GlyTouCan G05926FW

A composition-only glycan consisting of three hexosyl groups, nine acetaminohexosyl groups and one 6-deoxyhexosyl group (identities and connectivity unknown). Composition: Hex3 HexNAc9 dHex1.


Ala-Leu-Asp-Gly

A tetrapeptide composed of L-alanine, L-leucine, L-aspartic acid and glycine joined in sequence by peptide linkages.


name: 2,4-dimethyl-5-[(2-methylphenyl)hydrazinylidene]-3-pyrrolecarboxylic acid ethyl ester


Lys-Met-Met-Met

A tetrapeptide composed of L-lysine and three L-methionine units joined in sequence by peptide linkages.


A ceramide in which the sphingoid component is specified as (4E,8E)-sphinga-4,8-dienine.


A glycosyl alditol derivative consisting of D-galactopyranose, 2-acetamido-2-deoxy-D-glucopyranose and 2-acetamido-2-deoxy-D-galactitol residues joined in sequence by (1->4) and (1->3) glycosidic bonds.


Asp-Leu-Leu-Ser

A tetrapeptide composed of L-aspartic acid, two L-leucine units and L-serine joined in sequence by peptide linkages.


A glycophytoceramide having an alpha-D-glucopyranosyl residue at the O-1 position and an icosa-11,14-dienoyl group attached to the nitrogen.


ganglioside GM2 (18:0) methylamide

A sialotriaosylceramide that is ganglioside GM2 (18:0) in which the carboxy function of the sialic acid residue has been converted into an N-methylcarboxamide.


nitramine

Amines substituted at N with a nitro group (a contracted form of N-nitroamines); they are thus amides of nitric acid, and the class is composed of nitramide, O2NNH2, and its derivatives formed by substitution.


testosterone 3-(O-carboxymethyl)oxime

The oxime O-ether formed from testosterone and (aminooxy)acetic acid.


sphinganine-based sphingolipid

A family of sphingolipids that share a common structural feature, a sphinganine base backbone.


An amino disaccharide composed of D-galactose and N-acetyl-alpha-D-galactosaminyl residues in beta-(1->3) linkage.


2,5-dimethylphenyl isocyanate

An isocyanate that consists of phenyl isocyanate bearing two additional methyl substituents at positions 2 and 5.


An amino tetrasaccharide that is 2-acetamido-2-deoxy-alpha-D-galactopyranosyl-(1->3)-alpha-D-galactopyranosyl-(1->3)-2-acetamido-2-deoxy-D-galactopyranose in which the hydroxy group at position 2 of the central alpha-D-galactopyranosyl moiety has been glycosylated by an alpha-L-fucopyranosyl group.


An N-acyl-1-O-beta-D-glucosyl-15-methylhexadecasphing-4-enine in which the acyl group has 17 carbons and 4 double bonds and is 2-hydroxylated.


name: 6-methyl-2-[[(4-methylanilino)-oxomethyl]amino]-5,7-dihydro-4H-thieno[2,3-c]pyridine-3-carboxylic acid ethyl ester


Glu-Thr-Thr-Tyr

A tetrapeptide composed of L-glutamic acid, two L-threonine units and L-tyrosine joined in sequence by peptide linkages.


omega-conotoxin MVIIA

A heterodetic cyclic polypeptide consisting of the linear sequence Cys-Lys-Gly-Lys-Gly-Ala-Lys-Cys-Ser-Arg-Leu-Met-Tyr-Asp-Cys-Cys-Thr-Gly-Ser-Cys-Arg-Ser-Gly-Lys-Cys-NH2 with three disulfide bridges between cysteine residues 1-16, 8-20 and 15-25.  A neuronal N-type Ca(2+) channel blocker in mammalian and amphibian brain, it blocks release of GABA and glutamate at neuronal synapses. Used as a probe for calcium channel receptors, it is selective for different receptor subtypes. A synthetic form, named ziconotide, is an atypical analgesic agent for the amelioration of severe and chronic pain.


beta-D-glucosylceramide

Any glucosylceramide in which the glucosyl component has beta-D-configuration.


A beta-D-galactosyl-N-acylsphingosine in which the acyl group is specified as eicosanoyl.


SYNTHALIN

A member of the class of guanidines that is decane having guanidino groups at the 1- and 10-positions.


benzamide fungicide

An amide fungicide whose structure contains a benzamide moiety [ArC(=O)NR(1)R(2), where Ar represents phenyl or substituted phenyl].


A beta-D-glucosyl-(1<->1')-N-acylsphinganine in which the acyl group specified is eicosanoyl.


CHRYSOGESIDE A

A  glucosylceramide  isolated from Penicillium chrysogenum.


N-acyl-D-galactosylsphingosine

A sphingosine-based sphingolipid that is any N-acylsphingosine substituted at the O-1 position by a D-galactosyl residue.


phenylureas

Any member of the class of ureas in which at least one of the nitrogens of the urea moiety is substituted by a phenyl or substituted phenyl group.


D-phenylalanine derivative

A non-proteinogenic amino acid derivative resulting from reaction of D-phenylalanine at the amino group or the carboxy group, or from the replacement of any hydrogen of D-phenylalanine by a heteroatom.


An N-acyl-1-O-beta-D-glucosyl-15-methylhexadecasphing-4-enine in which the acyl group has 20 carbons and 0 double bonds.


Gly-L-Ala-L-Ala-D-Ala-D-Ala

A pentapeptide that consists of one glycyl, two L-alanyl and two D-alanyl residues coupled in sequence.


acetyl-L-serine

An acetyl-amino acid in which the amino acid specified is L-serine.


A beta-D-glucosylceramide in which a beta-D-glucosyl residue attached to the primary hydroxyl group of N-hexaacosanoyl-14-methylhexadecasphingosine. It is a metabolite of the nematode Caenorhabditis elegans.


cyprosulfamide

An N-sulfonylcarboxamide resulting from the formal condensation of the sulfonamide nitrogen of p-(cyclopropylaminocarbonyl)benzenesulfonamide with the carboxy group of O-methylsalicylic acid. It is a herbicide safener, used in conjunction with the Bayer herbicide tembotrione.


name: 1-(4-nitrophenyl)-1-cyclopentanecarboxylic acid 2-(diethylamino)ethyl ester


sialomonoglycosylceramide

A ganglioside in which the oligosaccharide portion is composed of an monosaccharide, to which one or more sialic acid residues are attached.


A ceramide in which the N-acyl moiety contains 24 carbons and 1 double bond, with the sphingoid base specified as C17-sphingosine.


glycosylceramide

A ceramide compound formed by the replacement of the glycosidic hydroxy group of a cyclic form of a monosaccharide (or derivative) by a ceramide group.


peginesatide

A heterodetic cyclic peptide composed of two identical 21-amino acid cyclic peptide units covalently bonded via a linker derived from iminodiacetic acid and beta-alanine to a lysine-branched poly(ethylene glycol) chain. Used for the treatment of anemia due to chronic kidney disease in patients on dialysis.


name: 1-[oxo(thiophen-2-yl)methyl]-2-pyrrolidinecarboxylic acid [2-[(3-carbamoyl-2-thiophenyl)amino]-2-oxoethyl] ester


name: 2-[[(3,5-dimethylphenyl)-oxomethyl]amino]acetic acid [2-[4-(2-naphthalenylsulfonyl)-1-piperazinyl]-2-oxoethyl] ester


azaxylylene

An imine formed formally from a quinodimethane by replacement of one or more atoms of the methylene groups by =NH or =NR.


mononitrotoluene

A nitrotoluene bearing a single nitro substituent at any position. A "closed class".


An eight-membered oligopeptide comprising L-leucine, L-serine, L-glutamic acid, L-threonine, O-sulfo-L-tyrosine, L-threonine, L-lysine and D-leucine residues coupled in sequence.


A glycopeptide that consists of (5R)-5-(beta-D-galactopyranosyloxy)lysyl, glycyl. alpha-glutamyl, glutaminyl, glycyl, prolyl, lysyl, glycyl, alpha-glutamyl and threonine residues coupled in sequence with an isostere-modified Ile-Ala-GlyPsi[(E)-CH=CH]Phe tetrapeptoid unit attached to the amino terminus.


bleomycin

A glycopeptide produced by the bacterium Streptomyces verticillus. The term, 'bleomycin' refers to a family of structurally related compounds. When used as an anti-cancer agent, the chemotherapeutical forms are primarily bleomycin A2 and B2.


An N-acyl-D-galactosylsphingosine in which the ceramide N-acyl group is composed of 24 carbons, 1 double bond and a hydroxy group at C2.


N-oleoylethanolamine phosphate

A N-acylethanolamine phosphate in which the acyl group is specifed as (9Z)-octadec-9-enoyl. It is a lysophosphatidic acid-1 (LPA1) receptor agonist.


A oligoglycosylceramide in which the oligoglycosyl component is a linear dodecasaccharide comprised of six galactose, one glucose, three N-acetylglucosamine, and three fucose units.


A sialotriaosylceramide consisting of the pentasaccharide beta-D-GalNAc-(1->4)-[alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)]-beta-D-Gal-(1->4)-beta-D-Glc attached to the primary hydroxy function of a ceramide in which the acyl function on nitrogen is stearoyl.


A fifteen-membered glycopeptide comprising glycyl, cyclopropylalanyl, alanyl, glycyl, cyclohexylalanyl, (5R)-5-(beta-D-galactopyranosyloxy)lysyl, glycyl. alpha-glutamyl, glutaminyl, glycyl, prolyl, lysyl, glycyl, alpha-glutamyl and threonine residues coupled in sequence.


A nucleoside analogue having 5-aminomethyl-2-thiouracil as the modified nucleobase.


name: 5-methyl-2-[[(4-nitrophenyl)-oxomethyl]hydrazo]-4-thiazolecarboxylic acid ethyl ester


A glycopentaosylceramide having beta-D-GlcA3S-(1->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc as the pentasaccharide component.


An N-acyl-1-O-beta-D-glucosyl-15-methylhexadecasphing-4-enine in which the acyl group has 26 carbons and 0 double bonds and is 2-hydroxylated.


An L-tyrosine derivative having an N(alpha)-acetyl substituent and a 4-arsonophenyldiazenyl group at the 3-position of the benzene ring.


A beta-D-galactosyl-(1<->1')-N-acylsphinganine in which the acyl group specified is eicosanoyl.


An alpha-Neu5Ac-(2->3)-beta-Gal-(1->3)-beta-GalNAc-(1->4)-[alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)]-beta-Gal-(1->4)-beta-Glc-(1<->1')-Cer in which the ceramide N-acyl group is specified as tetracosanoyl.


D-ornithine derivative

An ornithine derivative resulting from reaction of D-ornithine at the amino group, the carboxy group or the side-chain amino group, or from the replacement of any hydrogen of D-ornithine by a heteroatom.


name: 2-[[(4-methyl-2-thiazolyl)amino]-oxomethyl]-1-pyrrolidinecarboxylic acid 2-methylpropyl ester


vitamin B5

Any member of a group of vitamers that belong to the chemical structural class called pantothenic acids that exhibit biological activity against vitamin B5 deficiency. Deficiency of vitamin B5 is rare due to its widespread distribution in whole grain cereals, legumes and meat. Symptoms associated with vitamin B5 deficiency are difficult to asses since they are subtle and resemble those of other B vitamin deficiencies. The vitamers include (R)-pantothenic acid and its ionized and salt forms.


A beta-D-galactosyl-(1<->1')-N-acylsphinganine in which the acyl group specified is hexadecanoyl.


A glycophytoceramide having a 4-O-benzyl-alpha-D-galactosyl residue at the O-1 position and a hexacosanoyl group attached to the nitrogen. One of a series of an extensive set of 4"-O-alkylated alpha-GalCer analogues evaluated (PMID:30556652) as invariant natural killer T-cell (iNKT) antigens.


cyanides

Salts and C-organyl derivatives of hydrogen cyanide, HC#N.


Asp-Leu-Asp-Gln

A tetrapeptide composed of L-aspartic acid, L-leucine, L-aspartic acid, and L-glutamine joined in sequence by peptide linkages.


A C-nitro compound in which the nitro compound is ortho to the amino group and meta to the methyl group of p-toluidine.


A glycophytoceramide having an alpha-D-galactopyranosyl residue at the O-1 position and a 21-phenylhenicosanoyl group attached to the nitrogen.


C20 3-dehydrosphinganine

A sphingoid obtained by formal oxidation of the 3-hydroxy group of C20 sphinganine.


N-icosenoylphytosphingosine

A phytoceramide in which the acyl group contains  20 carbons and 1 double bond of unknown position. Formula:C38H74NO4


anilide fungicide

Any amide fungicide whose structure contains an anilide group.


4-guanidinobutanoic acid

The 4-guanidino derivative of butanoic acid.


A cerebroside in which the sugar head group is a hexose with unspecified stereochemistry attached to the primary hydroxyl group of N-acylsphinganine.


A galactosylceramide obtained by formal condensation of the carboxy group of any docosenoic acid with the amino group of beta-D-galactosyl-C14-sphingosine.


thiostrepton

A heterodetic cyclic peptide, in which the cyclisation step involves a formal lactonisation between the carboxy group of a quinaldic acid-based residue and a secondary alcohol. An antibiotic that inhibits bacterial protein synthesis. Also acts as an antitumor agent.


A glucosylceramide in which the sphingoid base is 15-methylhexadecasphing-4-enine and the D-glucosyl residue has beta-configuration at the anomeric centre.


nitroethene

A nitroalkene having ethenyl as the alkene portion.


A fatty acid derivative consisting of valeric acid substituted at C-5 with an N-(1-phenylcyclohexyl)amino group.


An N-acyl-1-O-beta-D-glucosyl-15-methylhexadecasphing-4-enine in which the acyl group has 28 carbons and 0 double bonds and is 2-hydroxylated.


name: 1-(3-fluorophenyl)-4-(4-hydroxy-3-methoxy-5-nitrophenyl)-4H-pyridine-3,5-dicarboxylic acid diethyl ester


alanine derivative

An amino acid derivative resulting from reaction of alanine at the amino group or the carboxy group, or from the replacement of any hydrogen of alanine by a heteroatom. The definition normally excludes peptides containing alanine residues.


An oligopeptide composed of L-glutamine, L-tyrosine, L-isoleucine, L-lysine, L-alanine, L-asparagine, L-serine, L-lysine, L-phenylalanine, L-isoleucine, glycine, L-isoleucine, L-threonine, L-glutamic acid and L-leucine joined in sequence by peptide linkages.


GlyTouCan G02886BB

A composition-only glycan consisting of six hexosyl groups and four acetaminohexosyl groups (identities and connectivity unknown). Composition: Hex6 HexNAc4.


An N-acyl-15-methylhexadecasphing-4-enine in which the acyl group has 23 carbons and 0 double bonds and is 2-hydroxylated.


An amino disaccharide comprised of N-acetyl-beta-D-glucosamine linked (1->4) to D-mannose.


A C20 dihydroceramide in which the ceramide N-acyl group is specified as 2-hydroxytetradecanoyl.


name: GIPC-anchor amidated glycine residue(1-)

description: A GIPC-anchor amidated amino acid where R1 represents the shingoid base, R2 is an acyl group, R3 can be an acyl group or an H, R4-8 can be other sugar groups, phosphoethanolamine or H.


N-benzoylurea

An N-acylurea that is urea in which one of the hydrogens is replaced by a benzoyl group.


tricarboxylic acid amide

A carboxamide resulting from the formal condensation of one or more carboxy groups of a tricarboxylic acid with the amino group of any amino compound.


metformin

A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.


Gly-Ser-Gly-Leu

A synthetic tetrapeptide comprising glycine, L-serine, glycine and L-leucine residues coupled in sequence.


alexidine

An amphipathic bisbiguanide with a structure consisting of two (2-ethylhexyl)guanide units linked by a hexamethylene bridge.


name: 2-butenedioic acid O4-[2-[(5-chloro-2-pyridinyl)amino]-2-oxoethyl] ester O1-ethyl ester


An amino trisaccharide consisting of alpha-L-fucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose and 2-acetamido-2-deoxy-D-galactopyranose residues joined in sequence by (1->3) and (1->6) glycosidic bonds.


D-serine derivative

A non-proteinogenic amino acid derivative resulting from reaction of D-serine at the amino group or the carboxy group, or from the replacement of any hydrogen of D-serine by a heteroatom.


A sialotetraosylceramide having alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-[alpha-Neu5Ac-(2->6)]-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc as the sialotetraosyl component.


An N-acyl-1-O-beta-D-glucosyl-15-methylhexadecasphing-4-enine in which the acyl group has 22 carbons and 2 double bonds.


aci-nitro compound

Organonitrogen compounds that have the general structure R(1)(R(2))C=N(O)OH (R(1),R(2) = H, organyl). They are tautomers of C-nitro compounds.


The N-glycosyl compound formed from the deoxy trisaccharide 3-deoxy-alpha-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc by replacement of the OH at the anomeric centre of the glucose residue by an acetylamino group.


TOLUENE DIISOCYANATE

A toluene meta-diisocyanate in which the isocyanato groups are at positions 2 and 4 relative to the methyl group on the benzene ring.


A beta-D-galactosyl-N-acylsphingosine in which the acyl group is specified as octadecanoyl.


N-hexadecanoylphytosphingosine

A phytoceramide compound having a hexadecanoyl group attached to the nitrogen atom.


Alexa Fluor 405

A fluorescent dye of absorption wavelength 401 nm and emission wavelength 421 nm derived from tris(triethylammonium)-8-hydroxypyrene-1,3,6-trisulfonate.


An L-tyrosine derivative in which the tyrosine skeleton is substituted with a methoxy group at C-3 of the phenyl ring and with a methyl group at the alpha carbon. It can also be regarded as a 3-O-methyl,alpha-methyl derivative of L-dopa.


An amino trisaccharide consisting of 2-acetamido-beta-D-galactopyranose, alpha-D-galactopyranose and D-galactopyranose residues joined in sequence by (1->3) and (1->4) glycosidic bonds.


epivancomycin

A glyopeptide that is vancomycin in which the terminal vancosamine of the disaccharide moiety is replaced by 4-epi-vancosamine.


ceramide

Ceramides (N-acyl-sphingoid bases) are a major subclass of sphingoid base derivatives with an amide-linked fatty acid. The fatty acids are typically saturated or monounsaturated with chain lengths from 14 to 26 carbon atoms; the presence of a hydroxyl group on carbon 2 is fairly common. Ceramides are generally precursors of more complex sphingolipids. In the illustrated generalised structure, R(1) = OH, OX (where X = acyl, glycosyl, phosphate, phosphonate, etc.), or H.


jawsamycin

A polyketide that is 5'-amino-5'-deoxy-3,4,5,6-tetrahydrouridine in which one of the hydrogens of the amino group is substituted by a (1E,3E)-1-[(1R,1'R,1''R,1'''R,2S,2'R,2''R,2'''S)-2'''-{(E)-2-[(1R,2R)-2-methylcyclopropyl]ethenyl}[1,1':2',1'':2'',1'''-quater(cyclopropan)]-2-yl]-5-oxopenta-1,3-dien-5-yl group. It is a metabolite isolated from the bacterium, Streptoverticillium fervens and targets the catalytic subunit of the fungal UDP-glycosyltransferase, the first step in the biosynthesis of glycosylphosphatidylinositol (GPI) anchors. It exhibits broad spectrum antifungal activity against several pathogenic fungi including Mucorales.


alpha-amanitin

A heterodetic cyclic peptide consisting of eight amino acid residues and containing a thioether bridge between a cysteine and a tryptophan residue. It is found in a number of poisonous mushrooms, including Amanita phalloides (the death cap), Galerina marginata, and and Conocybe filaris.


An amino disaccharide consisting of 2-acetamido-2-deoxy-beta-D-glucopyranose and D-mannopyranose residues joined in sequence by a (1->2) glycosidic bond.


vitamin B7

Any member of a group of vitamers that belong to the chemical structural class called biotins that exhibit biological activity against vitamin B7 deficiency. Vitamin B7 deficiency is very rare in individuals who take a normal balanced diet. Foods rich in biotin are egg yolk, liver, cereals, vegetables (spinach, mushrooms) and rice. Symptoms associated with vitamin B7 deficiency include thinning hair, scaly skin rashes around eyes, nose and mouth, and brittle nails. The vitamers include biotin and its ionized and salt forms.


urea-1-carboxylic acid

A member of the class of ureas that is urea in which one of the hydrogens has been replaced by a carboxy group.


N-dodecanoylphytosphingosine

A phytoceramide in which the ceramide N-acyl group is specified as dodecanoyl.


N-methylisoleucine

An isoleucine derivative that is isoleucine in which one of the hydrogens attached to the alpha-nitrogen is substituted by a methyl group.


D-proline derivative

A non-proteinogenic amino acid derivative resulting from reaction of D-proline at the amino group or the carboxy group, or from the replacement of any hydrogen of D-proline by a heteroatom.


ganglioside GM2 (16:0)

A sialotriaosylceramide that is N-acetyl-beta-D-galactosaminyl-(1->4)-alpha-N-acetylneuraminosyl-(2->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-N-acylsphingosine in which the acyl group on the sphingosine nitrogen is hexadecanoyl. A synthetic modification of the natural ganglioside GM2.


Pro-Trp-Val-Gly

A tetrapeptide composed of L-proline, L-tryptophan, L-valine, and glycine joined by peptide linkages.


L-proline derivative

A proteinogenic amino acid derivative resulting from reaction of L-proline at the amino group or the carboxy group, or from the replacement of any hydrogen of L-proline  by a heteroatom.


zofenoprilat arginine

An organoammonium salt obtained by combining zofenoprilat with one molar equivalent of L-arginine.


isoleucine derivative

An amino acid derivative resulting from reaction of isoleucine at the amino group or the carboxy group, or from the replacement of any hydrogen of isoleucine by a heteroatom. The definition normally excludes peptides containing isoleucine residues.


7-(methylsulfanyl)heptanal oxime

An aliphatic aldoxime resulting from the formal condensation of 7-(methylsulfanyl)heptanal with hydroxylamine.


An amino trisaccharide that is 2-acetamido-2-deoxy-beta-D-glucopyranose in which the hydroxy groups at positions 3 and 6 have each been glycosylated by an alpha-L-fucopyranosyl group.


Any phytoceramide in which the ceramide N-acyl group is carrying a 2R-hydroxy substituent.


A sialotetraosylceramide consisting of a alpha-Neu5Ac-(2->3)-[beta-D-Gal-(1->3)-beta-D-GalNAc-(1->4)]-beta-D-Gal-(1->4)-beta-D-Glc moiety attached via a glycosidic bond at position 1 of N-acylicosasphingosine.


β-guanidinopropionic acid

A guanidine compound bearing an N-(2-carboxyethyl) substituent. It is a creatine analogue that has been found to decreases plasma glucose levels


fosinoprilat

A phosphinic acid-containing N-acyl derivative of (4S)-cyclohexyl-L-proline. An inhibitor of angiotensin converting enzyme (ACE), it is used as the phosphinate ester pro-drug fosinopril for treatment of hypertension and chronic heart failure.


QUINALDINE BLUE

A cationic C3 cyanine dye having quinolin-2-yl units at each end.


A sialotetraosylceramide having beta-D-Gal-(1->3)-beta-D-GalNAc-(1->4)-[alpha-Neu5Ac-(2->3)]-beta-D-Gal-(1->4)-beta-D-Glc as the sialotetraosyl component.


An amino disaccharide consisting of an alpha-D-glucopyranose residue and a 2-acetamido-2-deoxy-D-glucopyranose residue joined in sequence by a (1->6) glycosidic bond.


A sialotetraosylceramide consisting of a branched hexasaccharide made up from two N-glycoloylneuraminyl residues, two galactose residues, one N-acetylgalactosamine residue and a glucose residue at the reducing end attached to the ceramide portion via a beta-linkage.


azobenzenes

Any member of the wide class of molecules that share the core azobenzene structure, comprising two phenyl rings linked by a N=N double bond, which may have different functional groups extending from the rings.


Neolacto-series glycosphingolipid

A series of oligoglycosylceramides having beta-D-galactosyl-(1-4)-N-acetyl-beta-D-glucosaminyl-(1-3)-beta-D-galactosyl-(1-4)-beta-D-glucose as the tetrasaccharide sequence root. The oligosaccharide portion can be elongated in a linear or branched form.


An amino trisaccharide consisting of 2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose and D-mannopyranose residues joined in sequence by (1->2) and (1->6) glycosidic bonds.


ganglioside GM2 (2:0)

A sialotriaosylceramide that is N-acetyl-beta-D-galactosaminyl-(1->4)-alpha-N-acetylneuraminosyl-(2->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-N-acylsphingosine in which the acyl group on the sphingosine nitrogen is acetyl. A synthetic modification of the natural ganglioside GM2.


An amino trisaccharide consisting of 2-acetamido-2-deoxy-beta-D-galactopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose and beta-D-galactopyranose residues joined in sequence by (1->4) and (1->3) glycosidic bonds.


CYCLOMONTANIN A

A  homodetic cyclic peptide composed of L-alanyl, L-tryptophyl, L-threonyl, L-prolylglycyl, L-leucyl and L-asparaginyl residues linked in a sequence. It is isolated from the seeds of Annona montana and has been shown to exhibit anti-inflammatory activity.


GlyTouCan G74724QE

A partially-defined glycan consisting of three hexosyl groups, 2 acetominohexosyl groups and a 6-deoxyhexosyl group (identities and connectivity unknown). Composition: Hex3 HexNAc2 6dHex1.


name: (3S)-3-(4-chlorophenyl)-4-oxo-3-propan-2-yldiazetidine-1,2-dicarboxylic acid dimethyl ester


A glycopentaosylceramide having N-acetyl-alpha-D-galactosaminyl-(1->3)-beta-D-galactosyl-(1->3)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl as the glycopentaosyl component.


An oligopeptide comprising five D-glutamic acid residues linked by peptidic bonds between the amino and gamma-carboxy groups.


(aminomethyl)phosphonic acid

A member of the class of phosphonic acids that is phosphonic acid substituted by an aminomethyl group. It is a metabolite of the herbicide glyphosate.


A cerebroside consisting of a  beta-D-glucosyl residue attached to the primary hydroxyl group of N-acyltetradecasphingosine.


monoamine molecular messenger

A group of neurotransmitters and neuromodulators that contain one amino group that is connected to an aromatic ring by ethylene group  (-CH2-CH2-). Monoamines are derived from the aromatic amino acids phenylalanine, tyrosine, histidine and tryptophan.


A glycopentaosylceramide having N-acetyl-beta-D-glucosaminyl-(1->3 or 6)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl as the glycopentaosyl component. The structural diagram shows the regioisomer with the terminal GlcNAc residue linked 1->6 to galactose.


A nLc5Cer where R1 is an undefined sphingoid base and R2 and undefined N-acyl chain.


An alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)-beta-Gal-(1->3)-beta-GalNAc-(1->4)-[alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)]-beta-Gal-(1->4)-beta-Glc-(1<->1')-Cer in which the ceramide N-acyl group is specified as octadecanoyl.


acetaldehyde oxime

An aldoxime derived from acetaldehyde.


An amino tetrasaccharide consisting of 2-acetamido-2-deoxy-alpha-D-galactopyranosyl, beta-D-galactopyranosyl, 2-acetamido-2-deoxy-beta-D-glucopyranosyl and 2-acetamido-2-deoxy-D-galactopyranoyl residues joined in sequence by (1->3) glycosidic linkages.


A glycopeptide that consists of phenylalanyl, (5R)-5-(beta-D-galactopyranosyloxy)lysyl, glycyl. alpha-glutamyl, glutaminyl, glycyl, prolyl, lysyl, glycyl, alpha-glutamyl and threonine residues coupled in sequence with an isostere-modified Ile-AlaPsi[(E)-CH=CH]Gly tripeptoid unit attached to the amino terminus.


GlyTouCan G23863VK

An amino decasaccharide consisting of five hexosyl groups, four acetaminohexosyl groups and a 6-deoxyhexosyl group (identities and connectivity unknown). Composition: Hex5 HexNAc4 6-dHex1.


A digalactosylceramide consisting of an alpha-D-galactosyl-(1->4)-beta-D-galactosyl moiety attached at position 1 of N-(pentacosanoyl)sphingosine via a glycosidic linkage.


A sialodecaosylceramide where the oligosaccharide component is made up from five galactose, three glucosamine, one glucose, one fucose and one sialose residue.


A synthetic seven-membered oligopeptide comprising Ac-Cha, Arg, MePhg, Met, Ala, Ser and tLeu-NH2 residues coupled in sequence.


Lacto-series glycosphingolipid

A series of oligoglycosylceramides having beta-D-galactosyl-(1-3)-N-acetyl-beta-D-glucosaminyl-(1-3)-beta-D-galactosyl-(1-4)-beta-D-glucose as the tetrasaccharide sequence root. The oligosaccharide portion can be elongated in a linear or branched form.


A sialotetraosylceramide having alpha-Neu5Ac-(2->6)-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc as the sialotetraosyl component.


An amino trisaccharide consisting of 2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose and beta-D-mannopyranose residues joined in sequence by (1->6) glycosidic bonds.


An aromatic amine that is diphenylmethane substituted at the 4-position of each benzene ring by an amino group.


microcystin LF

A microcystin consisting of D-alanyl, L-leucyl, (3S)-3-methyl-D-beta-aspartyl, L-phenylalanyl, (2S,3S,4E,6E,8S,9S)-3-amino-4,5,6,7-tetradehydro-9-methoxy-2,6,8-trimethyl-10-phenyldecanoyl, D-gamma-glutamyl, and 2,3-didehydro-N-methylalanyl residues joined into a 25-membered macrocycle.


An amino disaccharide that is beta-L-fucose in which the hydroxy group at position 3 has been converted into the corresponding 2-acetamido-2-deoxy-beta-D-glucopyranoside.


methyl N-acetylvalinate

A valine derivative with one of the amine hydrogens replaced by an acetyl group and the carboxylic acid hydrogen replaced by a methyl group.


An N-acyl-1-O-beta-D-glucosyl-15-methylhexadecasphing-4-enine in which the acyl group has 24 carbons and 4 double bonds and is 2-hydroxylated.


A glycophytoceramide having a 4-O-(4-chlorobenzyl)-alpha-D-galactosyl residue at the O-1 position and a hexacosanoyl group attached to the nitrogen. One of a series of an extensive set of 4"-O-alkylated alpha-GalCer analogues evaluated (PMID:30556652) as invariant natural killer T-cell (iNKT) antigens.


organophosphorus compound

An organophosphorus compound is formally a compound containing at least one carbon-phosphorus bond, but the term is often extended to include esters and thioesters.


hydroxyphenylacetaldehyde oxime

An  aldoxime that is acetaldehyde oxime in which one of the methyl hydrogens has been replaced by a hydroxyphenyl group.


chlormerodrin ((203)Hg)

Chlormerodrin containing the radioactive isotope (203)Hg. It was formerly used as a diagnostic aid in determination of renal function.


telavancin

A glycopeptide that is vancomycin substituted at position N-3'' by a 2-(decylamino)ethyl group and at position C-29 by a (phosphonomethyl)aminomethyl group. Used as its hydrochloride salt for treatment of adults with complicated skin and skin structure infections caused by bacteria.


An N-acyl-1-O-beta-D-glucosyl-15-methylhexadecasphing-4-enine in which the acyl group has 25 carbons and 2 double bonds.


A ceramide that is the N-stearoyl (octadecanoyl) derivative of 4-hydroxyeicosasphinganine.


ynamide

An alpha,beta-unsaturated monocarboxylic acid amide of general formula R(1)C#C-C(=O)NR(2)R(3) in which the amide C=O function is conjugated to a C#C triple bond at the alpha,beta position.


name: Cyclo-(L-Trp-L-Tyr), (C) Cyclo-(L-Trp-L-Ile), (D) Cyclo-(L-Trp-L-Leu)


N-acyl-beta-D-galactosylsphingosine

An N-acyl-D-galactosylsphingosine in which the anomeric configuration of the galactosyl residue is beta; sphingosine substituted at the O-1 position by a beta-D-galactosyl group and at the N-2 position by an acyl group.


An amino tetrasaccharide consisting of alpha-D-GlcNAc-(1->4)-beta-D-GlcA-(1->4)-alpha-D-GlcNAc-(1->4)-beta-D-GlcA in which the hydrogen attached to the anomeric oxygen is replaced by a 4-nitrophenyl group.


name: 2-[3-[2-[2-(difluoromethoxy)anilino]-2-oxoethyl]-4-oxo-2-thiazolidinylidene]acetic acid ethyl ester


An amino disaccharide consisting of D-galactopyranose at the non-reducing end joined by a (1->3) glycosidic linkage to N-acetyl-D-galactopyranosamine.


proline derivative

An amino acid derivative resulting from reaction of proline at the amino group or the carboxy group, or from the replacement of any hydrogen of proline by a heteroatom. The definition normally excludes peptides containing proline residues.


Pro-Val-Gly-Pro

A tetrapeptide composed of L-proline, L-valine, glycine, and L-proline joined by peptide linkages.


An N-acyl-15-methylhexadecasphing-4-enine in which the acyl group has 25 carbons and 0 double bonds.


An artificial glycosphingolipid composed of the ceramide mimetic C12L (CHEBI:190285) bound to a sialyl Lewis(x) [alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->4)-[alpha-L-Fuc-(1->3)]-D-GlcNAc] oligosaccharide via a beta-linkage.


An amino pentasaccharide consisting of three 2-acetamido-beta-D-glucopyranose residues, a 2-acetamido-alpha-D-glucopyranose residue and a further 2-acetamido-beta-D-glucopyranose residue joined in sequence by (1->4) glycosidic linkages.


A dihydrooceramide in which the ceramide N-acyl group is specified as 2-hydroxyoctacosanoyl.


A beta-alanine derivative obtained by formal condensation of the carboxy group of orotic acid with the amino group of beta-alanine. One of a series of mucosal-associated invariant T (MAIT) cell agonists.


Glu-Arg-Gly-Met-Thr

A pentapeptide composed of L-glutamic acid, L-arginine, glycine, L-methionine, and L-threonine joined in sequence by peptide linkages.


A C20 phytoceramide in which the ceramide N-acyl group is specified as octacosanoyl.


glycophytoceramide

A phytoceramide having at least one glycosyl group attached to either of its hydroxy groups.


A ceramide that is the N-(2-hydroxyoctadecanoyl) derivative of eicosasphinganine.


diamine

Any polyamine that contains two amino groups.


glutamic acid derivative

An amino acid derivative resulting from reaction of glutamic acid at the amino group or either of the carboxy groups, or from the replacement of any hydrogen by a heteroatom. The definition normally excludes peptides containing glutamic acid residues.


A member of the class of acetamides resulting from the formal condensation of the amino group of 1-phenylethylamine with 1 mol eq. of acetic acid.


propylenediamine

A diamine that is propane substituted by amino groups at positions 1 and 2. Propylenediamine is commonly used as a bidentate ligand in the formation of coordination complexes.


An amino disaccharide consisting of beta-D-galactopyranose and 2-acetamido-2-deoxy-beta-D-glucopyranose residuces linked in sequence by a (1->2) glycosidic bond.


D-histidine derivative

A non-proteinogenic amino acid derivative resulting from the formal reaction of D-histidine at the amino group, carboxy group, or the imidazolyl moiety, or from the replacement of any hydrogen of D-histidine by a heteroatom.


A N-acyl-15-methylhexadecasphing-4-enine in which the acyl group has 15 carbons and 0 double bonds.


An amino tetrasaccharide consisting of alpha-D-mannopyranosyl, beta-D-mannopyranosyl, 2-acetamido-alpha-D-glucopyranosyl and alpha-D-mannopyranosyl residues joined in sequence by (1->2), (1->3) and (1->6) glycosidic linkages.


6'-sialyl LacNAc-C12L

An artificial glycosphingolipid composed of the ceramide mimetic C12L (CHEBI:190285) bound to a 6'-sialyl LacNAc [alpha-Neu5Ac-(2->6)-beta-D-Gal-(1->4)-D-GlcNAc] oligosaccharide via a beta-linkage.


name: (2S)-2-[[(3,5-dimethoxyphenyl)-oxomethyl]amino]-3-methylbutanoic acid [2-oxo-2-(4-propan-2-ylanilino)ethyl] ester


N-oleoylphytosphingosine

A phytoceramide in which the N-acyl group is specified as oleoyl (9Z-octadecenoyl).


N-hydroxydebrisoquine O-glucuronide

A glucosiduronic acid that is the O-beta-D-glucuronide conjugate of N-hydroxydebrisoquine.


An amino trisaccharide consisting of alpha-L-fucopyranose, beta-D-galactopyranose and 2-acetamido-2-deoxy-D-glucopyranose residues joined in sequence by (1->2) and (1->4) glycosidic bonds.


name: 5-[(3-aminoanilino)-oxomethyl]-4-methyl-2-(1-oxobutylamino)-3-thiophenecarboxylic acid methyl ester


name: (2S, 3S, 4R)-2-[(2'R)-2'-hydroxytricosanoylamino]-1, 3, 4-octadecanetriol


A beta-D-glucosyl-(1<->1')-N-acylsphinganine in which the acyl group specified is (15Z)-tetracosenoyl.


The N-substituted diamine that is 1,4-phenylenediamine substituted at one N with an isopropyl group and at the other with a phenyl group.


N-octanoylphytosphingosine

A phytoceramide in which the N-acyl group is specified as octanoyl.


dicarboximide

An imide in which the two acyl substituents on nitrogen are carboacyl groups.


N,N,N',N'-tetramethylethylenediamine

An ethylenediamine derivative in which each nitrogen carries two methyl substituents. It is widely employed both as a ligand for metal ions and as a catalyst in organic polymerisation.


acetanilide

A member of the class of acetamides that is acetamide in which one of the hydrogens attached to the nitrogen is substituted by a phenyl group.


HC toxin

A homodetic cyclic tetrapeptide made up from L-alanyl, D-alanyl, L-prolyl and 2-amino-8-oxo-9,10-epoxydecanoyl residues.


aromatic amine

An amino compound in which the amino group is linked directly to an aromatic system.


Ala-Leu-Thr-Gln

A tetrapeptide composed of L-alanine, L-leucine, L-threonine, and L-glutamine joined in sequence by peptide linkages.


A glycophytoceramide having an alpha-D-galactopyranosyl residue at the O-1 position and a decanoyl group attached to the nitrogen.


A sialotetraosylceramide having alpha-Neu5Ac-(2->3)-beta-Gal-(1->3)-beta-GlcNAc-(1->3)-beta-Gal-(1->4)-beta-Glc as the sialotetraosyl component.


An amino disaccharide consisting of a D-galactopyranose residue and a 2-acetamido-2-deoxy-D-glucopyranose residue joined in sequence by a (1->4) glycosidic bond. The configuration of the anomeric centre of each residue is not stated.


aminocyclopyrachlor-triethylammonium

The triethylammonium salt of aminocyclopyrachlor.


diazo compound

Compounds containing a group =N2 attached to a single carbon atom. They are named by adding the prefix 'diazo-' to the name of the parent hydride or functional parent.


A glycotriaosylceramide having N-acetyl-beta-D-galactosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucose as the glycotriaosyl component.


A sialopentaosylceramide consisting of a linear heptasaccharide made up from two N-glycoloylneuraminyl residues, three galactose residues, one N-acetylglucosamine residue and a glucose residue at the reducing end attached to the ceramide portion via a beta-linkage.


A sialotriaosylceramide consisting of the tetrasaccharide beta-D-GalNAc-(1->4)-[alpha-Neu5Gc-(2->3)]-beta-D-Gal-(1->4)-beta-D-Glc attached to the primary hydroxy function of ceramide.


A beta-Gal-(1->3)-beta-GalNAc-(1->4)-[alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)]-beta-Gal-(1->4)-beta-Glc-(1<->1')-Cer in which the ceramide N-acyl group is specified as octadecanoyl.


GlyTouCan G04854VP

A composition-only glycan consisting of five hexosyl groups and eight acetaminohexosyl groups (identities and connectivity unknown). Composition: Hex5 HexNAc8.


A beta-D-galactosyl-(1<->1')-N-acylsphinganine in which the acyl group is specified as octadecanoyl.


TEBUFENOZIDE

A carbohydrazide that is hydrazine in which the amino hydrogens have been replaced by tert-butyl, 3,5-dimethylbenzoyl and 4-ethylbenzoyl groups respectively. It is an insecticide used widely against caterpillars.


A glycosyl alditol derivative consisting of beta-D-galactopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose and N-acetyl-D-galactosaminitol residues joined in sequence by (1->3) glycosidic bonds.


A ceramide that is the N-(2-hydroxyhexacosanoyl) derivative of eicosasphinganine.


glyoxime

An aldoxime obtained by formal condensation of glyoxal with two molar equivalents of hydroxylamine.


A glycosyl alditol derivative consisting of 2-acetamido-2-deoxy-D-glucopyranose, D-galactopyranose and 2-acetamido-2-deoxy-D-galactitol residues joined in sequence by (1->3) glycosidic bonds.


ethylenediamine derivative

Any organic amino compound that is a derivative of  ethylenediamine.


CERAMIDE

A dihydroceramide in which the ceramide acyl group is specified as acetyl.


name: 2-[(4-methylphenyl)sulfonylamino]acetic acid [2-(2,3-dihydroindol-1-yl)-2-oxoethyl] ester


An amino disaccharide comprising a beta-D-mannosyl residue linked (1->3) to an N-acetyl-D-glucosamine residue at the reducing end.


N-acylsphinganine

A ceramide consisting of sphinganine in which one of the amino hydrogens is substituted by a fatty acyl group.


ganglioside GM2 (18:1)

A sialotriaosylceramide that is N-acetyl-beta-D-galactosaminyl-(1->4)-alpha-N-acetylneuraminosyl-(2->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-N-acylsphingosine in which the acyl group on the sphingosine nitrogen is octadec-9-enoyl. A synthetic modification of the natural ganglioside GM2.


ganglioside GA2 II3,III3-bis-sulfate

A ganglioside GA2 compound sulfated at the 3-positions of both the galactose and galactosamine rings


Leu-enkephalin

A pentapeptide comprising L-tyrosine, glycine, glycine, L-phenylalanine and L-leucine residues joined in sequence by peptide linkages. It is an endogenous opioid peptide produced in vertebrate species, including rodents, primates and humans that results from decomposition of proenkephalin or dynorphin and exhibits antinociceptive properties.


GlyTouCan G29068FM

An partially-defined glycan that is an acetaminohexose in which the identity of the acetaminohexose and configuration of the anomeric centre is not known.


phenylalanine derivative

An amino acid derivative resulting from reaction of alanine at the amino group or the carboxy group, or from the replacement of any hydrogen of phenylalanine  by a heteroatom. The definition normally excludes peptides containing phenylalanine  residues.


An N-acyl-1-beta-D-glucosyl-15-methylhexadecasphing-4-enine in which the acyl group has 19 carbons and 0 double bonds.


N-(aminomethyl)urea

A member of the class of  ureas that is urea substituted by an aminomethyl group at the nitrogen atom.


N-octacosanoylphytosphingosine

A phytoceramide in which the ceramide N-acyl group is specified as octacosanoyl.


An N-(2-hydroxyacyl)sphinganine in which the 2-hydroxyacyl group has R-configuration.


An amino trisaccharide that is 2-acetamido-2-deoxy-D-glucopyranose in which the hydroxy groups at positions 3 and 4 have been converted into the corresponding beta-D-galactopyranosyl and 4,6-dideoxy-alpha-L-xylo-pyranosyl derivatives, respectively.


Ttds-Leu-Ser-Glu-Thr-Glu-Thr-D-Leu

A seven-membered oligopeptide comprising L-leucine, L-serine, L-glutamic acid, L-threonine, L-glutamic acid, L-threonine and D-leucine residues coupled in sequence, modified by insertion at the N-terminal position of the flexible and hydrophilic PEG chain 1,13-diamino-4,7,10-trioxatrideacne succinamic acid linker (Ttds).


A sphingoid obtained by formal oxidation of the 3-hydroxy group of tetradecasphinganine.


A fifteen-membered glycopeptide comprising glycyl, isoleucyl, alanyl, glycyl, phenylalanyl, (5R)-5-(beta-D-galactopyranosyloxy)lysyl, glycyl. alpha-glutamyl, glutaminyl, glycyl, prolyl, lysyl, glycyl, alpha-glutamyl and threonine residues coupled in sequence.


An amino trisaccharide consisting of beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose and 2-acetamido-2-deoxy-alpha-D-galactopyranose residues joined in sequence by (1->3) glycosidic bonds.


nitroso compound

Compounds having the nitroso group, -NO, attached to carbon, or to another element, most commonly nitrogen or oxygen.


A sphingolipid in which D-xylo-phytosphingosine is substituted on O-1 by an alpha-D-galactosyl group and on nitrogen by a hexacosanoyl group.


A D-galactosyl-N-acylsphingosine in which the ceramide N-acyl group is specified as (R)-2-hydroxybehenoyl.


An amino disaccharide that is 2-acetamido-2-deoxy-D-galactopyranose in which the hydroxy group at position 3 has been converted to the corresponding D-galactopyranoside. The stereochemistry at the anomeric position in each of the galactopyranose rings is not stated.


A N-acyl-beta-D-galactosylsphingosine in which the acyl group is tetracosananoyl.


A sialohexaosylceramide consisting of a linear heptasaccharide made up from one N-glycoloylneuraminic acid residue, three galactose residues, one N-acetylglucososamine residue and a glucose residue at the reducing end attached to the ceramide portion via a beta-linkage.


viomycin

A cyclic peptide antibiotic produced by the actinomycete Streptomyces puniceus, used in the treatment of tuberculosis.


A sialotriaosylceramide consisting of beta-D-GalNAc-(1->4)-[alpha-Neu5Ac-(2->3)]-beta-D-Gal-(1->4)-beta-D-Glc attached to the primary hydroxy function of ceramide(d18:1/24:1(15Z)).


An amino trisaccharide consisting of D-galactopyranose, 2-acetamido-2-deoxy-D-glucopyranose and 2-acetamido-2-deoxy-D-galactopyranose residues joined in sequence by (1->4) and (1->3) glycosidic bonds. The alpha/beta configuration at position 1 of each of the pyranose rings is not stated.


A D-galactosyl-N-acetyl-D-glucosaminyl-D-galactosyl-D-glucosylceramide containing beta-linkages exclusively.


N-eicosanoylsphinganine

A dihydroceramide in which the ceramide N-acyl group is specified as eicosanoyl


An N-acyl-1-O-beta-D-glucosyl-15-methylhexadecasphing-4-enine in which the acyl group has 24 carbons and 2 double bonds.


GlyTouCan G06042JP

A composition-only glycan consisting of two acetaminohexosyl groups and one 6-deoxyhexosyl group (identities and connectivity unknown). Composition: HexNAc2 dHex1.


PANTOTHENIC ACID, RACEMIC

A member of the class of pantothenic acids that is an amide formed from pantoic acid and beta-alanine.


N-behenoyl-D-galactosylsphingosine

An N-acyl-D-galactosylsphingosine in which the ceramide N-acyl group is specified as behenoyl (docosanoyl).


N-tricontanoylicosasphinganine

A C20 dihydroceramide in which the ceramide N-acyl group is specified as tricontanoyl.


An amino tetrasaccharide that is beta-D-Galp-(1->3)-beta-D-GlcpNAc-(1->6)-alpha-D-GalpNAc in which the hydroxy group at position 3 of the alpha-D-GalpNAc moiety has been glycosylated by a beta-D-Galp group.


N-tetradecanoylsphinganine

A dihydroceramide in which the ceramide N-acyl group is specified as tetradecanoyl (myristoyl).


C20 phytoceramide

A ceramide composed of C20 phytosphingosine having an unspecified fatty acyl group attached to the nitrogen.


N-D-glucosylarylamine

A hexosamine that is D-glucopyranose in which the hydroxy group at position 1 is replaced by an arylamino group.


An N-acyl-15-methylhexadecasphing-4-enine in which the acyl group has 20 carbons and 0 double bonds.


A D-galactosyl-N-acylphytosphingosine in which the galactosyl group has alpha-anomeric configuration and the acyl group on nitrogen is (4Z)-9-(2-decylcyclopropyl)non-4-enoyl.


C20 phytosphingosine

A sphingoid that is C20 sphinganine bearing an additional 4R-hydroxy substituent.


An N-acyl-1-O-beta-D-glucosyl-15-methylhexadecasphing-4-enine in which the acyl group has 17 carbons and 1 double bond.


A synthetic six-membered oligopeptide comprising Ac-Cha, Arg, Tic, Met, betaPhPro and [S(oxaz)L]-NMe2 residues coupled in sequence.


ganglioside X2

A  sialoheptaosylceramide consisting of a branched octasaccharide made up from one sialyl residue, three galactose residues, two N-acetylgalactosamine residues, one N-acetylglucosamine residue and a glucose residue at the reducing end attached to N-stearoylsphingosine via a beta-linkage.


N-carbamoylputrescine

An N-substituted putrescine where the N-substituent is a carbamoyl group.


The Z (anti) isomer of testosterone 3-(O-carboxymethyl)oxime.


name: 2-[[2-(4-morpholinyl)-1-oxoethyl]amino]-4-thiophen-2-yl-3-thiophenecarboxylic acid methyl ester


Asp-Met-Thr-Pro

A tetrapeptide composed of L-aspartic acid, L-methionine, L-threonine and L-proline joined in sequence by peptide linkages.


A nitroalkene that is 1-undecene substituted by a nitro group at position 11.  Metabolite observed in cancer metabolism.


monoazo compound

Compounds containing single -N=N- group.


A glycopentaosylceramide having N-acetyl-beta-D-glucosaminyl-(1->6)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucose as the pentasaccharide component.


A glycophytoceramide having a 6-deoxy-6-benzamido-alpha-D-galactosyl residue at the O-1 position and a hexacosanoyl group attached to the nitrogen.


An amino disaccharide consisting of 2-acetamido-2-deoxy-beta-D-glucopyranose and 2-acetamido-2-deoxy-beta-D-galactopyranose joined in sequence by a (1->6) glycosidic bond.


tertiary phosphine

A compound derived from phosphane by substituting three hydrogen atoms by hydrocarbyl groups.


An amino disaccharide consisting of beta-D-glucose linked via a (1->3)-glycosidic bond to N-acetyl-D-glucosamine.


ethylammonium trifluoroacetate

An organoammonium salt resulting from the mixing of equimolar amounts of trifluoroacetic acid and ethylamine.


trimethyl phosphite

An organophosphorus compound that is phosphane in which the three hydrogens are replaced by methoxy groups. It is an alkylating agent used primarily in the synthesis of organophosphate compounds.


A sialotetraosylceramide having alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-[alpha-Neu5Ac-(2->6)]-beta-D-GalNAc-(1->4)-[alpha-Neu5Ac-(2->3)]-beta-D-Gal-(1->4)-beta-D-Glc as the sialotetraosyl component.


propamidine

A polyether that is the bis(4-guanidinophenyl) ether of propane-1,3-diol. Used (as its isethionate salt) for the treatment of minor eye or eyelid infections, such as conjunctivitis and blepharitis.


An amino disaccharide consisting of beta-D-galactopyranose and 2-acetamido-2-deoxy-D-mannopyranose joined in sequence by a (1->4) glycosidic bond.


A sialotetraosylceramide having beta-D-Gal-(1->3)-beta-D-GalNAc-(1->4)-[alpha-Neu5Ac-(2->3)]-beta-D-Gal-(1->4)-beta-D-Glc as the sialotetraosyl component.


name: (3S)-3-(2-methylpropyl)-4-oxo-3-phenyldiazetidine-1,2-dicarboxylic acid dimethyl ester


ketimine

Any imine derived from a ketone.


selenocysteine derivative

An amino acid derivative resulting from reaction of selenocysteine at the amino group or the carboxy group, or from the replacement of any hydrogen of selenocysteine by a heteroatom. The definition normally excludes peptides containing selenocysteine residues.


hydrazines

Hydrazine (diazane) and its substituted derivatives.


GM1-GM1 dimer

A ganglioside derivative derived from two GM1 skeletons linked through their amino nitrogen atoms by an adipoyl (hexanedioyl) group.


N-methyl-N-picrylnitramine

A nitramine that is methylamine in which one of the hydrogens attached to the nitrogen is substituted by a nitro group while the other is substituted by a 2,4,6-trinitrophenyl group. A yellow crystalline powder, it is a high explosive, capable of being detonated by friction, shock, or a spark.


An amino disaccharide consisting of beta-D-galactopyranose and 2-acetamido-2-deoxy-beta-D-glucopyranose residues joined in sequence by a (1->6) glycosidic bond.


glycopentaosylceramide

An oligoglycosylceramide consisting of a glycopentaosyl moiety attached to the ceramide oxygen with an unspecified N-acyl substituent attached to the ceramide nitrogen.


N'-acetylisoniazid

A carbohydrazide resulting from the formal condensation of the carboxy group of isonicotinic acid with hydrazine and subsequent acetylation of the monosubstituted nitrogen atom.


An oligopeptide comprising nine D-glutamic acid residues linked by peptidic bonds between the amino and gamma-carboxy groups.


A sialotetraosylceramide consisting of a branched heptasaccharide made up from three sialyl residues, two galactose residues, one N-acetylglucosamine residue and a glucose residue at the reducing end attached to the ceramide portion via a beta-linkage.


A sialopentaosylceramide consisting of a branched nonasaccharide made up from one sialyl residue, two galactose residues, one L-fucose residue, one N-acetylglucosamine residue and one glucose residue, which at the reducing end is attached to the ceramide portion via a beta-linkage.


GlyTouCan G05897GU

A composition-only glycan consisting of three hexosyl groups, one acetaminohexosyl group and one 6-deoxyhexosyl group (identities and connectivity unknown). Composition: Hex3 HexNAc1 dHex1.


benazolin-dimethylammonium

An organoammonium salt resulting from the formal reaction of equimolar amounts of benazolin and dimethylamine.  It is used as a post-emergence herbicide for the control of annual weeds in crops.


An aminotrisaccharide consisting of beta-D-galactopyranosyl, 2-acetamido-beta-D-glucopyranosyl and alpha-L-fucopyranosyl residues joined in sequence by (1->3) and (1->4) glycosidic bonds.


An N-(2-hydroxyacyl)sphinganine in which the ceramide N-acyl group is specified as 2-hydroxyhexanoyl.


A dihydroceramide in which the ceramide N-acyl group is specified as (9Z)-octadecenoyl (oleoyl).


FLUNIXIN MEGLUMINE

An organoammonium salt obtained by combining flunixin with one molar equivalent of 1-deoxy-1-(methylamino)-D-glucitol. A relatively potent non-narcotic, nonsteroidal analgesic with anti-inflammatory, anti-endotoxic and anti-pyretic properties; used in veterinary medicine for treatment of horses, cattle and pigs.


hydroxymethylphosphonic acid

A phosphonic acid having a hydroxymethyl group attached to the phosphorus.


TYROCIDINE B

A homodetic cyclic decapeptide consisting of D-Phe, L-Pro, L-Trp, D-Phe, L-Asn, L-Gln, L-Tyr, L-Val, L-Orn, and L-Leu residues coupled in sequence and cyclised head-to-tail.


Glu-Lys-Trp-Ala

A tetrapeptide composed of L-glutamic acid, L-lysine, L-tryptophan and L-alanine joined in sequence by peptide linkages.


cyclo(ENPVVHFFFNIVTPRTP)

A 17-membered homodetic cyclic peptide comprising the sequence -Arg-Thr-Pro-Glu-Asp-Pro-Val-Val-His-Phe-Phe-Phe-Asp-Ile-Val-Thr-Pro-. Cyclic analogue with head-to-tail cyclisation of the myelin basic protein 83-99 (MBP83-99) immunodominant epitope with the lysyl residue at position 91 replaced by phenylalanyl [MBP83-99(F(91))].


A synthetic six-membered oligopeptide comprising Ac-Cha, Arg, Tic, Nle, betaPhPro and [S(oxaz)L]-NMe2 residues coupled in sequence.


An N-acyl-1-beta-D-glucosyl-15-methylhexadecasphing-4-enine in which the acyl group has 26 carbons and 1 double bond.


homocysteine derivative

A non-proteinogenic amino acid derivative resulting from reaction of homocysteine at the amino group, the carboxy group, or the side-chain amino group, or from the replacement of any hydrogen of homocysteine by a heteroatom. The definition normally excludes peptides containing homocysteine residues.


A phosphocerebroside consisting of galactosylceramide having an N-acetyl-alpha-D-glucosamine 1-phosphate moiety attached at the 6-position via a phosphodiester linkage.


An N-acyl-1-O-beta-D-glucosyl-15-methylhexadecasphing-4-enine in which the acyl group has 26 carbons and 2 double bonds and is 2-hydroxylated.


ganglioside

A molecule composed of a glycosphingolipid (ceramide and oligosaccharide) with one or more sialic acids linked on the sugar chain.


A sialotetraosylceramide having beta-D-Gal-(1->3)-[alpha-Neu5Ac-(2->6)]-D-GalNAc-(1->4)-beta-D-Gal-(1->4)-beta-D-Glc as the sialotetraosyl component.


A triamine comprising spermidine having a double bond at the 2-position.


name: (2S)-1-[oxo(thiophen-2-yl)methyl]-2-pyrrolidinecarboxylic acid [2-(2,4-dimethoxyanilino)-2-oxoethyl] ester


isoglutamine

A amino acid amide that is glutamic acid in which the carboxy group is replaced by an aminocarbonyl group.


An amino disaccharide consisting of N-acetyl-alpha-D-galactopyranosamine and N-acetyl-beta-D-galactofuranosamine residues joined in sequence by a (1->3) glycosidic linkage.


A galactosylceramide obtained by formal condensation of the carboxy group of docosanoic acid with the amino group of beta-D-galactosyl-(1<->1')-(4E,14Z)-sphingadienine.


A glycophytoceramide having an alpha-D-galactopyranosyl residue at the O-1 position and an 8-[(4-trifluoromethyl)phenyl]octanoyl group attached to the nitrogen.


An N-acyl-1-O-beta-D-glucosyl-15-methylhexadecasphing-4-enine in which the acyl group has 22 carbons and 0 double bonds and is 2-hydroxylated.


A beta-D-glucosylceramide in which a beta-D-glucosyl residue attached to the primary hydroxyl group of N-docosanoyl-14-methylhexadecasphingosine. It is a metabolite of the nematode Caenorhabditis elegans.