name: sister chromosome movement towards spindle pole involved in meiotic sister chromatid segregation

description: The directed movement of sister chromosomes from the center of the spindle towards the spindle poles, mediated by the shortening of microtubules attached to the chromosomes, during meiosis II.


meiotic strand invasion

category: biolink:BiologicalProcess biolink:Occurrent biolink:OntologyClass biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: The cell cycle process in which the nucleoprotein complex (composed of the broken single-strand DNA and the recombinase) searches and identifies a region of homology in intact duplex DNA. The broken single-strand DNA displaces the like strand and forms Watson-Crick base pairs with its complement, forming a duplex in which each strand is from one of the two recombining DNA molecules. This occurs during meiosis.


name: meiotic sister chromatid cohesion involved in meiosis I

description: The cell cycle process in which sister chromatids of a replicated chromosome are joined along the entire length of the chromosome during meiosis I.


name: mitotic intra-S DNA damage checkpoint signaling

category: biolink:Pathway biolink:OntologyClass biolink:BiologicalProcess biolink:Occurrent biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: A mitotic cell cycle checkpoint that slows DNA synthesis in response to DNA damage by the prevention of new origin firing and the stabilization of slow replication fork progression.


meiotic chromosome condensation

description: Compaction of chromatin structure prior to meiosis in eukaryotic cells.


mitotic spindle assembly

description: Mitotic bipolar spindle assembly begins with spindle microtubule nucleation from the separated spindle pole body, includes spindle elongation during prometaphase, and is complete when all kinetochores are stably attached the spindle, and the spindle assembly checkpoint is satisfied.


cell cycle G2/M phase transition

description: The cell cycle process by which a cell in G2 phase commits to M phase.


astral microtubule organization

description: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of astral microtubules, any of the spindle microtubules that radiate in all directions from the spindle poles.


astral microtubule depolymerization

description: The removal of tubulin heterodimers from one or both ends of an astral microtubule. An astral microtubule is any of the spindle microtubules that radiate in all directions from the spindle poles and are thought to contribute to the forces that separate the poles and position them in relation to the rest of the cell.


bacterial-type DNA replication

description: The DNA-dependent DNA replication, exemplified by prokaryotes, that occurs as part of the cell cycle. Prokaryotic DNA replication is bi-directional and originates at a single origin of replication on the circular genome.


synaptonemal complex assembly

description: The cell cycle process in which the synaptonemal complex is formed. This is a structure that holds paired chromosomes together during prophase I of meiosis and that promotes genetic recombination.


name: regulation of spindle attachment to meiosis I kinetochore

description: Any process that modulates the frequency, rate or extent of attachment of spindle microtubules to kinetochore involved in homologous chromosome segregation.


cohesin loading

description: The protein localization to chromatin by which a cohesin ring complex is topologically linked to DNA.


mitotic chromosome arm condensation

description: The cell cycle process in which chromosome arm chromatin structure is compacted prior to and during mitosis in eukaryotic cells.


name: positive regulation of mitotic actomyosin contractile ring contraction

description: Any process that activates or increases the frequency, rate or extent of mitotic actomyosin contractile ring contraction.


male meiosis sister chromatid cohesion

description: The joining of the sister chromatids of a replicated chromosome along the entire length of the chromosome that occurs during meiosis in a male.


name: microtubule anchoring at spindle pole body

description: Any process in which a microtubule is maintained in a specific location in a cell by attachment to a spindle pole body. Microtubules attach to spindle pole bodies at the minus end.


male meiotic nuclear division

description: A cell cycle process by which the cell nucleus divides as part of a meiotic cell cycle in the male germline.


name: germline cell cycle switching, mitotic to meiotic cell cycle

description: The process in which a germline cell switches cell cycle mode from mitotic to meiotic division.


meiotic spindle organization

description: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle during a meiotic cell cycle.


name: meiotic DNA double-strand break processing involved in reciprocal meiotic recombination

description: The cell cycle process in which the 5' to 3' exonucleolytic resection of the DNA at the site of the break to form a 3' single-strand DNA overhang occurs resulting in double strand break formation and repair through a double Holliday junction intermediate.


name: mitotic G2 cell size control checkpoint signaling

description: A signal transduction process that contributes to a cell size control checkpoint prior to the G2/M transition of mitosis.


name: ascospore wall (1->3)-beta-D-glucan biosynthetic process

description: The chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds, found in the walls of ascospores.


description: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the horsetail-astral array, a structure of astral microtubules that emanates from the spindle pole body during meiosis.


name: meiotic DNA repair synthesis involved in reciprocal meiotic recombination

description: The synthesis of DNA proceeding from the broken 3' single-strand DNA end that uses the homologous intact duplex as the template resulting in meiotic recombination. Meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate.


name: positive regulation of mitotic sister chromatid biorientation

description: Any process that activates or increases the frequency, rate or extent of mitotic sister chromatid biorientation, the mitotic cell cycle process in which sister chromatids establish stable, end-on attachments to the plus ends of microtubules emanating from opposite spindle poles, oriented such that separation can proceed.


name: mitotic spindle formation (spindle phase two)

description: The spindle organization process in which the spindle is maintained at a constant length during mitotic metaphase.


name: spindle assembly involved in male meiosis II

description: The formation of the spindle during meiosis II of a meiotic cell cycle in males. An example of this is found in Drosophila melanogaster.


name: negative regulation of syncytial blastoderm mitotic cell cycle

description: Any process that stops, prevents or reduces the rate or extent of progression through the syncytial blastoderm mitotic cell cycle.


name: cellular bud neck septin ring organization

description: Control of the formation, spatial distribution, and breakdown of a septin ring located at the bud neck.


name: meiotic spindle formation (spindle phase two)

description: The spindle organization process in which the spindle is maintained at a constant length during meiotic metaphase.


mitotic nuclear bridge organization

description: A mitotic cell cycle process which results in the assembly, arrangement, or disassembly of the mitotic nuclear bridge during closed mitosis.


DNA endoreduplication

description: Regulated re-replication of DNA within a single cell cycle, resulting in an increased cell ploidy. An example of this process occurs in the synthesis of Drosophila salivary gland cell polytene chromosomes.


mitotic G2/M transition checkpoint

description: A cell cycle checkpoint that detects and negatively regulates progression from G2 to M phase as part of a mitotic cell cycle.


establishment of spindle localization

description: The directed movement of the spindle to a specific location in the cell.


name: establishment of meiotic spindle localization

description: The cell cycle process in which the directed movement of the meiotic spindle to a specific location in the cell occurs.


name: mitotic DNA replication checkpoint signaling

description: A signal transduction process that contributes to a mitotic DNA replication checkpoint.


name: meiotic sister chromatid cohesion involved in meiosis II

description: The cell cycle process in which sister chromatids of a replicated chromosome are joined along the entire length of the chromosome during meiosis II.


meiosis I nuclear membrane reassembly

description: The reformation of the nuclear membranes during meiosis I.


anastral spindle assembly

description: The aggregation, arrangement and bonding together of a set of components to form the spindle, the array of microtubules and associated molecules that serves to move duplicated chromosomes apart, in the absence of centrosomes. Formation is initiated by the nucleation of microtubules (MTs) in the vicinity of condensed chromatin. MTs then attach to and congress around the chromatin due to activity of microtubule motors. A bipolar spindle is formed by focusing of the terminal ends of the MT array into spindle poles by molecular motors and cross-linking proteins.


mitotic nuclear pore complex reassembly

description: The cell cycle process in which nuclear pore complexes reform during mitotic cell division.


name: metaphase/anaphase transition of meiotic cell cycle

description: The cell cycle process in which a cell progresses from metaphase to anaphase as part of meiosis.


name: meiotic DNA double-strand break processing

description: The cell cycle process in which the 5' to 3' exonucleolytic resection of the DNA at the site of the break to form a 3' single-strand DNA overhang occurs. This takes place during meiosis.


female meiosis II

description: The cell cycle process in which the second meiotic division occurs in the female germline.


astral microtubule nucleation

description: The 'de novo' formation of an astral microtubule, in which tubulin heterodimers form metastable oligomeric aggregates, some of which go on to support formation of a complete microtubule.


mitotic spindle disassembly

description: The controlled breakdown of the spindle during a mitotic cell cycle.


mitotic cell cycle phase transition

description: The cell cycle process by which a cell commits to entering the next mitotic cell cycle phase.


name: protein localization to cell division site involved in cytokinesis, actomyosin contractile ring assembly

description: Any protein localization to cell division site that is involved in cytokinesis, actomyosin contractile ring assembly.


karyomere membrane fusion

description: Process whereby karyomere membranes fuse during interphase to form a single lobed nucleus.


name: DNA synthesis involved in mitotic DNA replication

description: Any DNA biosynthetic process that is involved in mitotic DNA replication.


name: establishment of mitotic spindle orientation

description: A cell cycle process that sets the alignment of mitotic spindle relative to other cellular structures.


name: homologous chromosome pairing at meiosis

description: The meiotic cell cycle process where side by side pairing and physical juxtaposition of homologous chromosomes is created during meiotic prophase. Homologous chromosome pairing begins when the chromosome arms begin to pair from the clustered telomeres and ends when synaptonemal complex or linear element assembly is complete.


name: mitotic actomyosin contractile ring maturation

description: The cellular process in which the mitotic contractile ring cytokinetic ring attains its fully functional state.


name: ascospore-type prospore membrane formation

description: The process in which the nascent membrane forms at the meiotic outer plaque and grows until closure occurs and forespores, or prospores, are formed.


name: positive regulation of spindle attachment to meiosis I kinetochore

description: Any process that activates or increases the frequency, rate or extent of attachment of spindle microtubules to kinetochore involved in homologous chromosome segregation.


name: kinetochore disassembly involved in meiotic chromosome organization

description: The cell cycle process in which outer kinetochore components delocalize from the centromere, contributing to the rearrangement of chromosomes into the orientation characteristic of meiotic prophase I.


name: spindle assembly involved in female meiosis

description: The aggregation, arrangement and bonding together of a set of components to form the spindle during a meiotic cell cycle in females. An example of this is found in Drosophila melanogaster.


cytoskeleton-dependent cytokinesis

description: A cytokinesis that involves the function of a set of proteins that are part of the microfilament or microtubule cytoskeleton.


meiotic spindle checkpoint signaling

description: A signal transduction process that contributes to a cell cycle checkpoint that delays the metaphase/anaphase transition of a meiotic nuclear division until the spindle is correctly assembled and that the chromosomes are attached to the spindle.


name: protein localization to mitotic actomyosin contractile ring

description: Any protein localization to actomyosin contractile ring that is involved in mitotic cytokinesis.


mitotic sister chromatid cohesion, arms

description: The cell cycle process in which the sister chromatids of a replicated chromosome are joined along the length of the chromosome arms during mitosis.


name: mitotic spindle orientation checkpoint signaling

description: A signaling process that monitors and signals errors in the placement or orientation of the spindle in the cell. This delays the completion of anaphase until errors are corrected.


name: mitotic G1 cell size control checkpoint signaling

description: A signal transduction process that contributes to a cell size control checkpoint during the G1/S transition of the cell cycle.


name: homologous chromosome movement towards spindle pole in meiosis I anaphase

description: The directed movement of homologous chromosomes from the center of the spindle towards the spindle poles, mediated by the shortening of microtubules attached to the chromosomes, during meiosis I anaphase.


male meiosis I

description: A cell cycle process comprising the steps by which a cell progresses through male meiosis I, the first meiotic division in the male germline.


mitotic cohesin loading

description: The protein localization to chromatin by which a cohesin ring complex is topologically linked to DNA as part of the mitotic cell cycle.


spindle assembly

description: The aggregation, arrangement and bonding together of a set of components to form the spindle, the array of microtubules and associated molecules that serves to move duplicated chromosomes apart.


name: negative regulation of mitotic actomyosin contractile ring contraction

description: Any process that stops, prevents or reduces the frequency, rate or extent of mitotic actomyosin contractile ring contraction.


name: nuclear DNA replication DNA duplex unwinding

description: Any DNA duplex unwinding that is involved in nuclear cell cycle DNA replication.


name: chromosome organization involved in meiotic cell cycle

description: A process of chromosome organization that is involved in a meiotic cell cycle.


oocyte karyosome formation

description: The chromosome organization process in which meiotic chromosomes in the oocyte nucleus cluster together to form a compact spherical structure called the karyosome.


microsporogenesis

description: The process in which the microsporocyte undergoes meiosis, giving rise to four haploid microspores.


name: meiotic mismatch repair involved in reciprocal meiotic recombination

description: A system for the identification and correction of base-base mismatches, small insertion-deletion loops, and regions of heterology that are present in duplex DNA formed with strands from two recombining molecules resulting in meiotic recombination. Meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate.


mitotic sister chromatid cohesion

description: The cell cycle process in which the sister chromatids of a replicated chromosome are joined along the entire length of the chromosome, from their formation in S phase through metaphase during a mitotic cell cycle. This cohesion cycle is critical for high fidelity chromosome transmission.


name: female meiosis sister chromatid cohesion

description: The joining of the sister chromatids of a replicated chromosome along the entire length of the chromosome that occurs during meiosis in a female.


name: regulation of mitotic actomyosin contractile ring contraction

description: Any process that modulates the frequency, rate or extent of mitotic actomyosin contractile ring contraction.


name: regulation of actomyosin contractile ring contraction

description: Any process that modulates the frequency, rate or extent of contraction of the actomyosin ring involved in cytokinesis that takes place as part of a cell cycle.


name: pre-replicative complex assembly involved in premeiotic DNA replication

description: Any pre-replicative complex assembly involved in meiotic cell cycle DNA replication.


name: vesicle fusion with nuclear membrane involved in mitotic nuclear envelope reassembly

description: The cell cycle process that results in the joining of the lipid bilayer membrane around a vesicle with the lipid bilayer membrane around the nucleus, and contributes to mitotic nuclear envelope reassembly.


name: mitotic chromosome movement towards spindle pole

description: The cell cycle process in which the directed movement of chromosomes from the center of the spindle towards the spindle poles occurs. This mediates by the shortening of microtubules attached to the chromosomes, during mitosis.


name: mitotic nuclear pore complex disassembly

description: The mitotic cell cycle process in which the controlled breakdown of the nuclear pores occurs during open or closed mitosis.


name: pre-replicative complex assembly involved in cell cycle DNA replication

description: Any pre-replicative complex assembly that is involved in cell cycle DNA replication.


name: mitotic cell size control checkpoint signaling

description: A signal transduction process that contributes to a cell size control checkpoint during mitosis.


establishment of spindle orientation

description: Any process that set the alignment of spindle relative to other cellular structures.


sister chromatid segregation

description: The cell cycle process in which sister chromatids are organized and then physically separated and apportioned to two or more sets.


name: ascospore wall beta-glucan biosynthetic process

description: The chemical reactions and pathways resulting in the formation of beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of ascospores.


mitotic cell cycle checkpoint signaling

description: A signaling process that ensures accurate chromosome replication and segregation by preventing progression through a mitotic cell cycle until conditions are suitable for the cell to proceed to the next stage.


name: mitotic DNA replication DNA duplex unwinding

description: Any DNA duplex unwinding involved in mitotic cell cycle DNA replication.


name: meiotic DNA double-strand break formation involved in meiotic gene conversion

description: The cell cycle process in which double-strand breaks are generated at defined hotspots throughout the genome during meiosis I resulting in meiotic gene conversion. Meiotic gene conversion is the cell cycle process in which genetic information is transferred from one helix to another.


name: microtubule anchoring at mitotic spindle pole body

description: Any process in which a microtubule is maintained in a specific location in a cell by attachment to a mitotic spindle pole body. Microtubules attach to spindle pole bodies at the minus end.


name: meiotic strand invasion involved in meiotic gene conversion

description: The cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate resulting in meiotic recombination.


name: pre-replicative complex assembly involved in bacterial-type DNA replication

description: The aggregation, arrangement and bonding together of a set of components to form the bacterial pre-replicative complex, a protein-DNA complex that forms at the bacterial oriC during the initial step of DNA replication and allows the origin to become competent, or 'licensed', for replication.


female meiotic nuclear division

description: A cell cycle process by which the cell nucleus divides as part of a meiotic cell cycle in the female germline.


name: double-strand break repair involved in meiotic recombination

description: The repair of double-strand breaks in DNA via homologous and nonhomologous mechanisms to reform a continuous DNA helix that contributes to reciprocal meiotic recombination.


name: meiotic mismatch repair involved in meiotic gene conversion

description: A system for the identification and correction of base-base mismatches, small insertion-deletion loops, and regions of heterology that are present in duplex DNA formed with strands from two recombining molecules resulting in meiotic gene conversion. Meiotic gene conversion is the cell cycle process in which genetic information is transferred from one helix to another.


centriole replication

description: The cell cycle process in which a daughter centriole is formed perpendicular to an existing centriole. An immature centriole contains a ninefold radially symmetric array of single microtubules; mature centrioles consist of a radial array of nine microtubule triplets, doublets, or singlets depending upon the species and cell type. Duplicated centrioles also become the ciliary basal body in cells that form cilia during G0.


linear element maturation

description: The meiotic cell cycle chromosome organization process in which LinE complexes closely associate with chromatin during meiotic prophase to form mature linear elements.


karyomere assembly

description: The process where the nuclear membrane engulfs condensed chromosomes to form karyomeres during M phase of the mitotic cell cycle.


name: microtubule plus-end directed mitotic chromosome migration

description: The cell cycle process in which chromosomes that are laterally attached to one or more mitotic spindle microtubules migrate towards the spindle equator via plus-end-directed movement along the microtubules. This process is part of mitotic metaphase plate congression.


name: response to meiotic recombination checkpoint signaling

description: A process that occurs in response to signals generated as a result of meiotic recombination checkpoint signaling.


cell cycle DNA replication

description: The DNA-dependent DNA replication that takes place as part of the cell cycle.


name: male meiotic chromosome movement towards spindle pole

description: The directed movement of chromosomes in the center of the spindle towards the spindle poles, mediated by the shortening of microtubules attached to the chromosomes, during male meiosis.


name: meiotic DNA integrity checkpoint signaling

description: A signal transduction process that controls cell cycle progression in response to changes in DNA structure by monitoring the integrity of the DNA during meiosis. The DNA integrity checkpoint begins with detection of DNA damage, defects in DNA structure or DNA replication, and ends with signal transduction.


name: metaphase/anaphase transition of cell cycle

description: The cell cycle process in which a cell progresses from metaphase to anaphase as part of the cell cycle.


name: meiotic spindle assembly checkpoint signaling

description: A signal transduction process that contributes to a meiotic spindle assembly checkpoint, that delays the metaphase/anaphase transition of a meiotic cell cycle until the spindle is correctly assembled and chromosomes are attached to the spindle.


meiotic centromere clustering

description: The process by which centromeres/kinetochores attach to and migrate along microtubules to become localized to clusters at the spindle pole body during a meiotic prometaphase I.


megasporogenesis

description: The process in which the megasporocyte undergoes meiosis, giving rise to four haploid megaspores in the nucellus.


meiotic telomere clustering

description: The cell cycle process in which the dynamic reorganization of telomeres occurs in early meiotic prophase, during which meiotic chromosome ends are gathered in a bouquet arrangement at the inner surface of the nuclear envelope proximal to the spindle pole body. This plays an important role in progression through meiosis and precedes synapsis.


meiosis II nuclear membrane reassembly

description: The reformation of the nuclear membrane during meiosis II.


meiotic spindle disassembly

description: The controlled breakdown of the spindle during a meiotic cell cycle.


cell cycle G1/S phase transition

description: The cell cycle process by which a cell in G1 phase commits to S phase.


name: spindle assembly involved in female meiosis I

description: The aggregation, arrangement and bonding together of a set of components to form the spindle during meiosis I of a meiotic cell cycle in females. An example of this is found in Drosophila melanogaster.


name: cell cycle DNA replication DNA unwinding

description: Any DNA unwinding that is involved in cell cycle DNA replication.


spore membrane bending pathway

description: The process in which a bending force is generated in the prospore membrane to form the characteristic curved shape of the prospore.


name: spindle assembly involved in male meiosis

description: The aggregation, arrangement and bonding together of a set of components to form the spindle during a meiotic cell cycle in males. An example of this is found in Drosophila melanogaster.


name: mitotic spindle formation (spindle phase one)

description: The cell cycle process in which the distance is lengthened between poles of the mitotic spindle during mitotic prophase.


meiotic gene conversion

description: The cell cycle process in which genetic information is transferred from one helix to another. It often occurs in association with general genetic recombination events, and is believed to be a straightforward consequence of the mechanisms of general recombination and DNA repair. For example, meiosis might yield three copies of the maternal version of an allele and only one copy of the paternal allele, indicating that one of the two copies of the paternal allele has been changed to a copy of the maternal allele.


name: centromere detachment from spindle pole body involved in meiotic chromosome organization

description: The cell cycle process in which centromeres dissociate from the spindle pole body, contributing to the rearrangement of chromosomes into the orientation characteristic of meiotic prophase I.


achiasmate meiosis I

description: The first division of meiosis in which homologous chromosomes are paired and segregated from each other, occurring in the constitutive absence of chiasmata.


generative cell mitosis

description: The process in which the generative cell divides by mitosis to form two haploid cells. These will subsequently differentiate into sperm cells.


name: mitotic sister chromatid cohesion, telomeric

description: The cell cycle process in which telomeres of sister chromatids are joined during mitosis.


name: establishment of mitotic spindle asymmetry

description: The mitotic spindle organization process by which a mitotic spindle becomes asymmetric either in position or structure.


nuclear DNA replication

description: The DNA-dependent DNA replication that occurs in the nucleus of eukaryotic organisms as part of the cell cycle.


nuclear chromosome segregation

description: The process in which genetic material, in the form of nuclear chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. Nuclear chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles.


mitotic nuclear membrane organization

description: A mitotic cell cycle process which results in the assembly, arrangement, or disassembly of the nuclear inner or outer membrane during mitosis.


premeiotic DNA replication

description: The replication of DNA that precedes meiotic cell division.


sperm karyosome formation

description: The chromosome organization process in which meiotic chromosomes in the spem nucleus cluster together to form a compact spherical structure called the karyosome.


name: meiotic sister chromatid cohesion, centromeric

description: The cell cycle process in which centromeres of sister chromatids are joined during meiosis.


mitotic nuclear membrane biogenesis

description: A process in which the nuclear inner or outer membrane is synthesized, aggregates, and bonds together during mitotic nuclear division.


mitotic DNA replication

description: Any nuclear DNA replication that is involved in a mitotic cell cycle.


midbody abscission

description: The process by which the midbody, the cytoplasmic bridge that connects the two prospective daughter cells, is severed at the end of mitotic cytokinesis, resulting in two separate daughter cells.


name: spindle assembly involved in female meiosis II

description: The aggregation, arrangement and bonding together of a set of components to form the spindle during meiosis II of a meiotic cell cycle in females. An example of this is found in Drosophila melanogaster.


meiosis II nuclear membrane disassembly

description: The controlled breakdown of the nuclear membranes during the second division of meiosis.


meiosis II

description: The second nuclear division of meiosis, in which the two chromatids in each chromosome are separated, resulting in four daughter nuclei from the two nuclei produced in meiosis II.


mitotic cell cycle process

description: A process that is part of the mitotic cell cycle.


meiotic nuclear membrane reassembly

description: The cell cycle process in which the reformation of the nuclear membranes during meiosis occurs.


name: premeiotic DNA replication DNA duplex unwinding

description: Any DNA duplex unwinding involved in meiotic cell cycle DNA replication.


mitotic DNA-templated DNA replication

description: A DNA replication process that uses parental DNA as a template for the DNA-dependent DNA polymerases that synthesize the new strands during the mitotic cell cycle.


name: establishment of mitotic spindle orientation involved in growth plate cartilage chondrocyte division

description: A cell cycle process that sets the alignment of mitotic spindle relative to other cellular structures and contributes to oriented chondrocyte division in the growth plate.


name: mitotic telomere maintenance via semi-conservative replication

description: Any telomere maintenance via semi-conservative replication that is involved in mitotic cell cycle.


name: mitotic cytokinesis checkpoint signaling

description: A signaling process that contributes to a mitotic cell cycle checkpoint that detects a defect in cytokinesis and prevents further rounds of nuclear division until cytokinesis is completed.


meiotic nuclear division

description: One of the two nuclear divisions that occur as part of the meiotic cell cycle.


name: positive regulation of syncytial blastoderm mitotic cell cycle

description: Any process that activates or increases the rate or extent of progression through the syncytial blastoderm mitotic cell cycle.


cleavage furrow ingression

description: Advancement of the cleavage furrow from the outside of the cell inward towards the center of the cell. The cleavage furrow acts as a 'purse string' which draws tight to separate daughter cells during cytokinesis and partition the cytoplasm between the two daughter cells. The furrow ingresses until a cytoplasmic bridge is formed.


name: protein localization to cell division site involved in mitotic actomyosin contractile ring assembly

description: Any protein localization to cell division site that is involved in mitotic actomyosin contractile ring assembly.


meiotic strand displacement

description: The cell cycle process in which the broken 3' single-strand DNA molecule that formed heteroduplex DNA with its complement in an intact duplex DNA is rejected. The Watson-Crick base pairing in the original duplex is restored. The rejected 3' single-strand DNA molecule reanneals with its original complement to reform two intact duplex molecules. This occurs during meiosis.


meiotic sister chromatid segregation

description: The cell cycle process in which sister chromatids are organized and then physically separated and randomly apportioned to two sets during the second division of the meiotic cell cycle.


name: meiotic DNA double-strand break formation

description: The cell cycle process in which double-strand breaks are generated at defined hotspots throughout the genome during meiosis I. This results in the initiation of meiotic recombination.


meiotic mismatch repair

description: A system for the identification and correction of base-base mismatches, small insertion-deletion loops, and regions of heterology that are present in duplex DNA formed with strands from two recombining molecules. Correction of the mismatch can result in non-Mendelian segregation of alleles following meiosis.


name: establishment of mitotic spindle localization

description: The cell cycle process in which the directed movement of the mitotic spindle to a specific location in the cell occurs.


name: bacterial-type DNA replication DNA duplex unwinding

description: Any DNA duplex unwinding that is involved in bacterial-type DNA replication.


meiosis I

description: The first meiotic nuclear division in which homologous chromosomes are paired and segregated from each other, producing two haploid daughter nuclei.


name: mitotic DNA integrity checkpoint signaling

description: A signaling process that controls cell cycle progression in response to changes in DNA structure by monitoring the integrity of the DNA during mitosis. The DNA integrity checkpoint begins with detection of DNA damage, defects in DNA structure or DNA replication, and ends with signal transduction.


name: membrane addition at site of mitotic cytokinesis

description: A mitotic cell cycle process involved in the net addition of membrane at the site of cytokinesis; includes vesicle recruitment and fusion, local lipid synthesis and insertion.


name: pre-replicative complex assembly involved in nuclear cell cycle DNA replication

description: The aggregation, arrangement and bonding together of a set of components to form the nuclear pre-replicative complex, a protein-DNA complex that forms at the eukaryotic DNA replication origin and is required for replication initiation.


name: female meiotic chromosome movement towards spindle pole

description: The directed movement of chromosomes in the center of the spindle towards the spindle poles, mediated by the shortening of microtubules attached to the chromosomes, during female meiosis.


name: anastral spindle assembly involved in male meiosis

description: The aggregation, arrangement and bonding together of a set of components to form the anastral spindle in male meiotic cells.


name: mitotic spindle elongation (spindle phase three)

description: The cell cycle process in which the distance is lengthened between poles of the mitotic spindle during mitotic anaphase B.


name: meiotic DNA double-strand break processing involved in meiotic gene conversion

description: The cell cycle process in which the 5' to 3' exonucleolytic resection of the DNA at the site of the break to form a 3' single-strand DNA overhang resulting in the transfer of genetic information from one helix to another.


mitotic nuclear division

description: A mitotic cell cycle process comprising the steps by which the nucleus of a eukaryotic cell divides; the process involves condensation of chromosomal DNA into a highly compacted form. Canonically, mitosis produces two daughter nuclei whose chromosome complement is identical to that of the mother cell.


name: signal transduction involved in cytokinesis checkpoint

description: A signal transduction process that contributes to a cytokinesis checkpoint.


cleavage furrow formation

description: Generation of the cleavage furrow, a shallow groove in the cell surface near the old metaphase plate that marks the site of cytokinesis. This process includes the recruitment and localized activation of signals such as RhoA at the site of the future furrow to ensure that furrowing initiates at the correct site in the cell.


name: membrane addition at site of cytokinesis

description: Any process involved in the net addition of membrane at the site of cytokinesis; includes vesicle recruitment and fusion, local lipid synthesis and insertion.


meiotic sister chromatid cohesion

description: The cell cycle process in which sister chromatids of a replicated chromosome are joined along the entire length of the chromosome during meiosis.


name: protein localization to meiotic spindle pole body

description: A process in which a protein is transported to, or maintained in, a location within a meiotic spindle pole body.


name: microtubule bundle formation involved in mitotic spindle midzone assembly

description: Any microtubule bundle formation that is involved in spindle midzone assembly involved in mitosis.


chromosome separation

description: The cell cycle process in which paired chromosomes are detached from each other. Chromosome separation begins with the release of cohesin complexes from chromosomes; in budding yeast, this includes the cleavage of cohesin complexes along the chromosome arms, followed by the separation of the centromeric regions. Chromosome separation also includes formation of chromatid axes mediated by condensins, and ends with the disentangling of inter-sister catenation catalyzed by topoisomerase II (topo II).


mitotic DNA damage checkpoint signaling

description: A signal transduction process involved in mitotic DNA damage checkpoint.


meiosis I nuclear membrane disassembly

description: The controlled breakdown of the nuclear membranes during the first division of meiosis.


name: meiotic telomere tethering at nuclear periphery

description: The process in which a telomere is maintained in a specific location at the nuclear periphery, as part of a meiotic cell cycle.


name: zygote asymmetric cytokinesis in embryo sac

description: The division of the zygote in a plane perpendicular to the long axis of the embryo sac to produce a larger basal cell near the micropyle and a small terminal cell close to what was the central cell and is now the developing endosperm. An example of this process is found in Arabidopsis thaliana.


name: chromosome movement towards spindle pole

description: The directed movement of chromosomes in the center of the spindle towards the spindle poles, mediated by the shortening of microtubules attached to the chromosomes.


name: metaphase/anaphase transition of meiosis I

description: The cell cycle process in which a cell progresses from metaphase to anaphase as part of meiosis I.


meiotic spindle assembly

description: The aggregation, arrangement and bonding together of a set of components to form the spindle that contributes to the process of meiosis.


name: meiotic DNA double-strand break formation involved in reciprocal meiotic recombination

description: The cell cycle process in which double-strand breaks are generated at defined hotspots throughout the genome during meiosis I resulting in meiotic recombination. Meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate.


name: meiosis I spindle assembly checkpoint signaling

description: Any spindle assembly checkpoint that is involved in meiosis I.


actomyosin contractile ring maturation

description: The cellular process in which the contractile ring cytokinetic ring attains its fully functional state.


name: mitotic G2 DNA damage checkpoint signaling

description: A mitotic cell cycle checkpoint that detects and negatively regulates progression through the G2/M transition of the cell cycle in response to DNA damage.


name: meiotic strand invasion involved in reciprocal meiotic recombination

description: The cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate resulting in meiotic recombination. Meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate.


name: mitotic G1 DNA damage checkpoint signaling

description: A signal transduction process that contributes to a mitotic cell cycle G1/S transition DNA damage checkpoint.


name: mitotic chromosome centromere condensation

description: The cell cycle process in which centromere chromatin structure is compacted prior to and during mitosis.


name: meiotic DNA repair synthesis involved in meiotic gene conversion

description: The synthesis of DNA proceeding from the broken 3' single-strand DNA end that uses the homologous intact duplex as the template resulting in meiotic gene conversion. Meiotic gene conversion is the cell cycle process in which genetic information is transferred from one helix to another.


name: mitotic morphogenesis checkpoint signaling

description: A signaling process that contributes to a mitotic cell cycle checkpoint which delays mitotic onset in response to perturbations that affect cell shape via the actin cytoskeleton, septin organization, small cell size, and/or the extent of membrane growth.


karyosome formation

description: The chromosome organization process in which meiotic chromosomes in the germ cell nucleus cluster together to form a compact spherical structure called the karyosome.


name: meiotic recombination checkpoint signaling

description: A signaling process that contributes to a meiotic recombination checkpoint, that acts during late prophase I (pachytene) and prevents segregation of homologous chromosomes until recombination is completed, ensuring proper distribution of the genetic material to the gametes.


female meiosis I

description: The cell cycle process in which the first meiotic division occurs in the female germline.


name: mitotic actomyosin contractile ring assembly

description: Any actomyosin contractile ring assembly that is involved in mitotic cytokinesis.


chromosome segregation

description: The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. In eukaryotes, chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles.


name: microtubule cytoskeleton organization involved in mitosis

description: Any microtubule cytoskeleton organization that is involved in mitosis.


name: actomyosin contractile ring organization

description: A process which results in the assembly, arrangement of constituent parts, or disassembly of an actomyosin contractile ring.


cell cycle phase transition

description: The cell cycle process by which a cell commits to entering the next cell cycle phase.


name: sodium channel subunit beta-3, signal peptide removed form (human)

description: A sodium channel subunit beta-3 (human) that has had the signal peptide removed. UniProtKB:Q9NY72, 23-215.


name: GATOR2 complex protein MIOS methylated 2 (human)

description: A GATOR2 complex protein MIOS (human) that has been methylated on the residue at the position equivalent to Cys-191 of the amino acid sequence represented by UniProtKB:Q9NXC5-1. Example: UniProtKB:Q9NXC5-1, Cys-191, MOD:00660.


name: BARX1_HUMAN Homeobox protein BarH-like 1 (sprot)

description: A homeobox protein BarH-like 1 that is encoded in the genome of human.


homeobox protein BarH-like 1

A protein that is a translation product of the human BARX1 gene or a 1:1 ortholog thereof.


homeobox protein BarH-like 1 isoform 1

A homeobox protein BarH-like 1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9HBU1-1 or a 1:1 ortholog thereof.


name: homeobox protein BarH-like 1 isoform 1 (mouse)

description: A homeobox protein BarH-like 1 isoform 1 that is encoded in the genome of mouse.


name: BARX1_MOUSE Homeobox protein BarH-like 1 (sprot)

description: A homeobox protein BarH-like 1 that is encoded in the genome of mouse.


name: homeobox protein BarH-like 1 isoform 1 (human)

description: A homeobox protein BarH-like 1 isoform 1 that is encoded in the genome of human.


name: BAX1B_CHICK Homeobox protein BarH-like 1b (sprot)

description: A homeobox protein BarH-like 1 that is encoded in the genome of chicken.


name: homeobox protein BarH-like 1 isoform h2 (human)

description: A homeobox protein BarH-like 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9HBU1-2.


name: BARX1_DANRE Homeobox protein BarH-like 1 (sprot)

description: A homeobox protein BarH-like 1 that is encoded in the genome of zebrafish.


cyclin-T1 isoform h1 (human)

A cyclin-T1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O60563-1.


name: PO3F1_DANRE POU domain, class 3, transcription factor 1 (sprot)

description: A POU domain, class 3, transcription factor 1 that is encoded in the genome of zebrafish.


name: 6-methyl-4-oxoquinolizine-1,3-dicarboxylic acid diethyl ester


name: YFCD_ECOLI Uncharacterized Nudix hydrolase YfcD (sprot)

description: An uncharacterized Nudix hydrolase YfcD that is encoded in the genome of Escherichia coli K-12.


uncharacterized Nudix hydrolase YfcD

A protein that is a translation product of the Escherichia coli K-12 yfcD gene or a 1:1 ortholog thereof.


name: bromodomain adjacent to zinc finger domain protein 2A methylated 2 (human)

description: A bromodomain adjacent to zinc finger domain protein 2A (human) that has been methylated on the residue at the position equivalent to Cys-1720 of the amino acid sequence represented by UniProtKB:Q9UIF9-1. Example: UniProtKB:Q9UIF9-1, Cys-1720, MOD:00660.


name: gamma-aminobutyric acid receptor subunit rho-2 isoform 2 (mouse)

description: A gamma-aminobutyric acid receptor subunit rho-2 isoform 2 that is encoded in the genome of mouse.


name: phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN sequence variant Q245*, initiator methionine removed form (human)

description: A phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN (human) that has has been truncated after the position equivalent to Pro-244 of the amino acid sequence represented by UniProtKB:P60484-1 and that has had the initiator methionine removed. Example: UniProtKB:P60484-1, 2-244.


name: GSTUP_ARATH Glutathione S-transferase U25 (sprot)

description: A protein that is a translation product of the GSTU25 gene in Arabidopsis thaliana.


degenerin unc-8 isoform b (worm)

A degenerin unc-8 (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q21974-2.


UNC8_CAEEL Degenerin unc-8 (sprot)

A protein that is a translation product of the unc-8 gene in worm.


degenerin unc-8 isoform c (worm)

A degenerin unc-8 (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q21974-3.


degenerin unc-8 isoform a (worm)

A degenerin unc-8 (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q21974-1.


degenerin unc-8 isoform d (worm)

A degenerin unc-8 (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q21974-4.


ELAEODENDROSIDE W

A cardenolide glycoside that is 3,5,11,14-tetrahydroxy-19-oxocard-20(22)-enolide glycosylated at position 3 by a beta-allosyl-(1->4)-beta-6-deoxyallosyl group. Isolated from Elaeodendron alluaudianum, it exhibits antiproliferative activity against human ovarian cancer and human histiocytic lymphoma cell lines.


dysgerminoma of ovary

category: biolink:Disease biolink:DiseaseOrPhenotypicFeature biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing

description: A malignant germ cell tumor arising from the ovary. Morphologically, it is identical to seminoma and consists of a monotonous population of germ cells with abundant pale cytoplasm and uniform nuclei. The stroma invariably contains chronic inflammatory cells, mostly T-lymphocytes. It responds to chemotherapy or radiotherapy and the prognosis relates to the tumor stage.


pediatric ovarian dysgerminoma

description: A dysgerminoma that arises from the ovary and occurs in children.


name: G protein-activated inward rectifier potassium channel 3 isoform 1 (rat)

description: A G protein-activated inward rectifier potassium channel 3 isoform 1 that is encoded in the genome of rat.


name: KCNJ9_RAT G protein-activated inward rectifier potassium channel 3 (sprot)

description: A G protein-activated inward rectifier potassium channel 3 that is encoded in the genome of rat.


name: proteasome subunit beta type-5 isoform h3 (human)

description: A proteasome subunit beta type-5 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P28074-3.


name: integrin alpha-7 isoform rAlpha-7X1A (rat)

description: An integrin alpha-7 (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q63258-2.


protocadherin-15 isoform m2 (mouse)

A protocadherin-15 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q99PJ1-2.


name: SERC_SCHPO Putative phosphoserine aminotransferase (sprot)

description: A phosphoserine aminotransferase that is encoded in the genome of Schizosaccharomyces pombe 972h-.


name: tyrosine-protein kinase JAK3 phosphorylated 2 (human)

description: A tyrosine-protein kinase JAK3 (human) that has been phosphorylated on the residues at the positions equivalent to Tyr-904 and Tyr-939 of the amino acid sequence represented by UniProtKB:P52333-1. Example: UniProtKB:P52333-1, Tyr-904/Tyr-939, MOD:00048.


name: peroxisomal trans-2-enoyl-CoA reductase isoform 1

description: A peroxisomal trans-2-enoyl-CoA reductase that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9BY49-1 or a 1:1 ortholog thereof.


name: peroxisomal trans-2-enoyl-CoA reductase isoform 1 (human)

description: A peroxisomal trans-2-enoyl-CoA reductase isoform 1 that is encoded in the genome of human.


name: peroxisomal trans-2-enoyl-CoA reductase isoform 1 (rat)

description: A peroxisomal trans-2-enoyl-CoA reductase isoform 1 that is encoded in the genome of rat.


name: peroxisomal trans-2-enoyl-CoA reductase isoform 1 (mouse)

description: A peroxisomal trans-2-enoyl-CoA reductase isoform 1 that is encoded in the genome of mouse.


name: SCM2A_DANRE Calcium-binding mitochondrial carrier protein SCaMC-2-A (sprot)

description: A protein that is a translation product of the slc25a25a gene in zebrafish.


name: OFP3_ARATH Transcription repressor OFP3 (sprot)

description: A protein that is a translation product of the OFP3 gene in Arabidopsis thaliana.


name: CD209 antigen-like protein B isoform m3 (mouse)

description: A CD209 antigen-like protein B (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8CJ91-3.


spermine oxidase isoform 1 (human)

A spermine oxidase isoform 1 that is encoded in the genome of human.


spermine oxidase

A protein that is a translation product of the human SMOX gene or a 1:1 ortholog thereof.


spermine oxidase isoform 1 (mouse)

A spermine oxidase isoform 1 that is encoded in the genome of mouse.


SMOX_MOUSE Spermine oxidase (sprot)

A spermine oxidase that is encoded in the genome of mouse.


spermine oxidase isoform 10 (mouse)

A spermine oxidase isoform 3 that is encoded in the genome of mouse.


spermine oxidase isoform m7 (mouse)

A spermine oxidase (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q99K82-7.


spermine oxidase isoform 6

A spermine oxidase that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9NWM0-6 or a 1:1 ortholog thereof.


SMOX_HUMAN Spermine oxidase (sprot)

A spermine oxidase that is encoded in the genome of human.


spermine oxidase isoform m8 (mouse)

A spermine oxidase (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q99K82-8.


spermine oxidase isoform 6 (human)

A spermine oxidase isoform 6 that is encoded in the genome of human.


spermine oxidase isoform h2 (human)

A spermine oxidase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9NWM0-2.


spermine oxidase isoform 1

A spermine oxidase that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9NWM0-1 or a 1:1 ortholog thereof.


spermine oxidase isoform m6 (mouse)

A spermine oxidase (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q99K82-6.


spermine oxidase isoform 3

A spermine oxidase that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9NWM0-3 or a 1:1 ortholog thereof.


spermine oxidase isoform m4 (mouse)

A spermine oxidase (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q99K82-4.


spermine oxidase isoform m5 (mouse)

A spermine oxidase (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q99K82-5.


spermine oxidase isoform h5 (human)

A spermine oxidase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9NWM0-5.


spermine oxidase isoform 3 (human)

A spermine oxidase isoform 3 that is encoded in the genome of human.


spermine oxidase isoform m9 (mouse)

A spermine oxidase (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q99K82-9.


spermine oxidase isoform h4 (human)

A spermine oxidase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9NWM0-4.


spermine oxidase isoform 2 (mouse)

A spermine oxidase isoform 6 that is encoded in the genome of mouse.


name: UBR7_DICDI Putative E3 ubiquitin-protein ligase ubr7 (sprot)

description: A putative E3 ubiquitin-protein ligase UBR7 that is encoded in the genome of Dictyostelium discoideum.


name: myosin-9, initiator methionine removed form (human)

description: A myosin-9 (human) that has had the initiator methionine removed. UniProtKB:P35579, 2-1960.


HALOXYFOP

A monocarboxylic acid that is 2-phenoxypropanoic acid in which the hydrogen at the para position of the phenyl ring has been replaced by a [3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy group.


(S)-haloxyfop

A 2-(4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}phenoxy)propanoic acid that has S configuration. It is the least-active enantiomer of the (racemic) herbicide haloxyfop.


HALOXYFOP-R-METHYL

A 2-(4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}phenoxy)propanoic acid that has R configuration. It is the most active enantiomer of the (racemic) herbicide haloxyfop and is used (particularly as the corresponding methyl and ethoxyethyl ester proherbicides (haloxyfop-P-methyl and haloxyfop-P-etotyl, respectively) to control annual and perrenial grasses in a variety of crops.


name: TRXR1_CAEEL Thioredoxin reductase 1 (sprot)

description: A protein that is a translation product of the trxr-1 gene in worm.


name: neuropeptide-like protein 38 isoform b (worm)

description: A neuropeptide-like protein 38 (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:G3MU46-1.


name: NLP38_CAEEL Neuropeptide-like protein 38 (sprot)

description: A protein that is a translation product of the nlp-38 gene in worm.


name: neuropeptide-like protein 38 isoform a (worm)

description: A neuropeptide-like protein 38 (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:G3MU46-2.


GAL2B_DANRE Galanin receptor 2b (sprot)

A protein that is a translation product of the galr2b gene in zebrafish.


name: protocadherin gamma-B1 cysteinylated 1 (human)

description: A protocadherin gamma-B1 (human) that has been cysteinylated on the residue at the position equivalent to Cys-380 of the amino acid sequence represented by UniProtKB:Q9Y5G3-1. Example: UniProtKB:Q9Y5G3-1, Cys-380, MOD:00765.


name: phosphatidylethanolamine-binding protein 1 isoform 1 (human)

description: A phosphatidylethanolamine-binding protein 1 isoform 1 that is encoded in the genome of human.


name: YLNA_SCHPO Uncharacterized protein PB8E5.10 (sprot)

description: A protein that is a translation product of the SPAPB8E5.10 gene in Schizosaccharomyces pombe 972h-.


autophagy protein 5 isoform 1 (rat)

An autophagy protein 5 isoform 1 that is encoded in the genome of rat.


vitamin D deficiency

description: Abnormally low level of 25-hydroxyvitamin D in the blood.


name: Infant-Type Hemispheric Glioma, ROS1-Altered

description: A high-grade cellular astrocytoma that arises in the cerebral hemisphere and occurs in early childhood. It is characterized by receptor tyrosine kinase fusions in the ROS1 gene.


septin-6 phosphorylated 1 (mouse)

A septin-6 phosphorylated 1 in mouse. UniProtKB:Q9R1T4, Ser-416, MOD:00046.


name: Bcl2-associated agonist of cell death isoform 1 phosphorylated 6 (mouse)

description: A Bcl2-associated agonist of cell death isoform 1 phosphorylated 6 in mouse. UniProtKB:Q61337-1, Ser-128/Ser-136, MOD:00046.


name: heparan sulfate 2-O-sulfotransferase pipe isoform 12 (fruit fly)

description: A heparan sulfate 2-O-sulfotransferase pipe (fruit fly) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q86BJ3-12.


Sesterviolene B

A sesterterpene that is produced by a sesterterpene synthase from Streptomyces violens


name: TBCC domain-containing protein 1 isoform h1 (human)

description: A TBCC domain-containing protein 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9NVR7-1.


name: RL141_ARATH Large ribosomal subunit protein eL14z (sprot)

description: A protein that is a translation product of the RPL14A gene in Arabidopsis thaliana.


name: cilium assembly protein DZIP1 isoform h3 (human)

description: A cilium assembly protein DZIP1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q86YF9-3.


name: peptidyl-lysine dihydroxylation to 4,5-dihydroxy-L-lysine

description: The dihydroxylation of peptidyl-lysine to peptidyl-4,5-dihydroxy-L-lysine.


name: peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine

description: The hydroxylation of peptidyl-lysine to peptidyl-5-hydroxy-L-lysine.


name: peptidyl-lysine hydroxylation involved in bacterial-type EF-P lysine modification

description: Any peptidyl-lysine hydroxylation that is involved in bacterial-type EF-P lysine modification.


name: peptidyl-N6,N6,N6-trimethyl-lysine hydroxylation to peptidyl-N6,N6,N6-trimethyl-5-hydroxy-L-lysine

description: The hydroxylation of peptidyl-N6,N6,N6-trimethyl-L-lysine to form peptidyl-N6,N6,N6-trimethyl-5-hydroxy-L-lysine.


name: peptidyl-lysine hydroxylation to 4-hydroxy-L-lysine

description: The hydroxylation of peptidyl-lysine to peptidyl-4-hydroxy-L-lysine.


name: YCBK_ECOLI Uncharacterized protein YcbK (sprot)

description: An uncharacterized protein YcbK that is encoded in the genome of Escherichia coli K-12.


protein LRATD1 isoform 1

A protein LRATD1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q96KN4-1 or a 1:1 ortholog thereof.


protein LRATD1 isoform 1 (human)

A protein LRATD1 isoform 1 that is encoded in the genome of human.


protein FAM84A isoform 1 (mouse)

A protein LRATD1 isoform 1 that is encoded in the genome of mouse.


name: IQM6_ARATH IQ domain-containing protein IQM6 (sprot)

description: A protein that is a translation product of the IQM6 gene in Arabidopsis thaliana.


name: junctional adhesion molecule C isoform 1 (rat)

description: A junctional adhesion molecule C isoform 1 that is encoded in the genome of rat.


name: ephrin type-A receptor 7 isoform 1 (chicken)

description: An ephrin type-A receptor 7 isoform 2 that is encoded in the genome of chicken.


name: EPHA7_CHICK Ephrin type-A receptor 7 (sprot)

description: An ephrin type-A receptor 7 that is encoded in the genome of chicken.


An inorganic anion that is a polyboron cluster made up from twelve boron atoms with a net charge of -2.


name: FSH-Producing Pituitary Neuroendocrine Tumor

description: A pituitary neuroendocrine tumor that produces follicle-stimulating hormone (FSH).


Anterior Pituitary Gland Neoplasm

description: A neoplasm arising from the anterior lobe of the pituitary gland. The vast majority are pituitary neuroendocrine tumors (formerly pituitary adenomas).


name: Immature PIT1 Lineage Pituitary Neuroendocrine Tumor

description: An immature pituitary neuroendocrine tumor composed of PIT1-lineage adenohypophyseal cells with cytologic atypia and limited differentiation towards thyrotroph, somatotroph, and/or lactotroph cells. (WHO)


name: Pituitary Neuroendocrine Tumor without Distinct Lineage Differentiation

description: A pituitary neuroendocrine tumor that belongs to more than one adenohypophysial cell lineage or does not show evidence of adenohypophysial hormonal immunoreactivity and specific adenohypophysial cell derivation.


name: Locally Advanced Pituitary Neuroendocrine Tumor

description: Pituitary neuroendocrine tumor that has spread from its original site of growth to nearby tissues or lymph nodes.


name: Somatotroph-Lactotroph Pituitary Neuroendocrine Tumor

description: A pituitary neuroendocrine tumor that produces both growth hormone and prolactin.


name: Pituitary Neuroendocrine Tumor of PIT1-Lineage

description: A pituitary neuroendocrine tumor arising from PIT1-lineage adenohypophysial cells.


pituitary gland adenoma

description: A non-metastasizing tumor that arises from the adenohypophysial cells of the anterior lobe of the pituitary gland. The tumor can be hormonally functioning or not. The diagnosis can be based on imaging studies and/or radioimmunoassays. Due to its location in the sella turcica, expansion of the tumor mass can impinge on the optic chiasm or involve the temporal lobe, third ventricle and posterior fossa A frequently associated physical finding is bitemporal hemianopsia which may progress to further visual loss.


name: Densely Granulated Corticotroph Pituitary Neuroendocrine Tumor

description: A corticotroph pituitary neuroendocrine tumor composed of basophilic PAS-positive cells that are diffusely and strongly positive for ACTH, consistent with the abundance of secretory granules seen at the ultrastructural level. (WHO)


name: Pituitary Neuroendocrine Tumor of SF1-Lineage

description: A pituitary neuroendocrine tumor arising from SF1-lineage adenohypophysial cells.


name: Pituitary Neuroendocrine Tumor, Not Otherwise Specified

description: A pituitary neuroendocrine tumor in which further characterization regarding subtyping is not available.


Crooke Cell Tumor

description: A corticotroph pituitary tumor composed of cells with Crooke hyaline change. Ring-like cytokeratin expression is typical of these neoplasms. ACTH expression is dislocated to the cell periphery and juxtanuclear region. Ultrastructurally, intermediate filaments are arranged in a ring-like pattern. (WHO)


name: Mammosomatotroph Pituitary Neuroendocrine Tumor

description: A pituitary neuroendocrine tumor composed of acidophilic cells that produce both growth hormone and prolactin. Immunohistochemical studies reveal the presence of these two hormones localized in the same cell.


name: Null Cell Pituitary Neuroendocrine Tumor

description: A non-functioning pituitary neuroendocrine tumor without hormonal immunoreactivity or evidence of specific adenohypophyseal cell derivation.


name: LH-Producing Pituitary Neuroendocrine Tumor

description: A pituitary neuroendocrine tumor that produces luteinizing hormone (LH).


non-functioning pituitary adenoma

description: A hormone producing or non-producing pituitary gland adenoma not associated with a hormonal syndrome.


Pituitary macroadenoma

category: biolink:PhenotypicFeature biolink:DiseaseOrPhenotypicFeature biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing

description: A pituitary gland adenoma that is larger than 10mm.


name: growth hormone-producing pituitary gland adenoma

description: An adenoma of the anterior lobe of the pituitary gland that produces growth hormone. The vast majority of cases are hormonally functioning and are associated with either gigantism or acromegaly.


name: Plurimorphous Plurihormonal Pituitary Neuroendocrine Tumor

description: A plurihormonal pituitary neuroendocrine tumor consisting of two or more different cell lineages. (WHO)


name: Non-Functioning Densely Granulated Corticotroph Pituitary Neuroendocrine Tumor

description: A densely granulated corticotroph pituitary neuroendocrine tumor not associated with a hormonal syndrome.


name: ACTH-producing pituitary gland carcinoma

description: A rare, hormonally functioning or non-functioning pituitary gland adenocarcinoma that produces corticotropin. It may be associated with Cushing disease.


name: Non-Functioning Pituitary Neuroendocrine Tumor/Macroadenoma

description: A pituitary neuroendocrine tumor/macroadenoma not associated with a hormonal syndrome.


pituitary blastoma

description: A pituitary cancer that is characterized by features of Cushing disease, with elevated blood ACTH levels and hypercortisolism arising within the fetal anterior pituitary and associated with DICER1 mutations.


name: mixed somatotroph-lactotroph pituitary gland adenoma

description: An infrequent pituitary gland adenoma composed of an admixture of acidophilic and chromophobic cells that produce growth hormone and prolactin respectively. Unlike mammosomatotroph adenomas, these two hormones are not localized in the same cell by immunohistochemistry.


name: Functioning Pituitary Neuroendocrine Tumor/Macroadenoma

description: A pituitary neuroendocrine tumor/macroadenoma associated with a hormonal syndrome.


name: Functioning Pituitary Neuroendocrine Tumor/Microadenoma

description: A pituitary neuroendocrine tumor/microadenoma associated with a hormonal syndrome.


name: Recurrent Anterior Pituitary Gland Neoplasm

description: The reemergence of a pituitary gland neoplasm after a period of remission.


pituitary adenocarcinoma

description: A rare adenocarcinoma with poor prognosis, arising from the adenohypophysial cells of the anterior lobe of the pituitary gland or pre-existing adenomas. The majority are hormonally functioning neoplasms, usually producing prolactin or ACTH. The diagnosis is based on the presence of metastases. Syndromes associated with pituitary gland carcinomas include hyperprolactinemia, Cushing disease, and acromegaly.


name: Double Pituitary Neuroendocrine Tumors of Distinct Lineages

description: Pituitary neuroendocrine tumors composed of adenohypopheseal cells of two lineages or a null cell tumor in combination with a lineage-specific pituitary neuroendocrine tumor in the same gland.


name: Non-Functioning Corticotroph Pituitary Neuroendocrine Tumor

description: Corticotroph pituitary neuroendocrine tumor not associated with a hormonal syndrome.


name: prolactin-producing pituitary gland carcinoma

description: A rare, hormonally functioning or non-functioning pituitary gland adenocarcinoma that produces prolactin.


name: growth hormone-producing pituitary gland carcinoma

description: A rare, hormonally functioning or non-functioning pituitary gland adenocarcinoma that produces growth hormone. It may be associated with acromegaly.


name: Monomorphous Plurihormonal Pituitary Neuroendocrine Tumor

description: A plurihormonal pituitary neuroendocrine tumor consisting of a single cell type producing two (or rarely more) hormones. (WHO)


Ectopic Pituitary Neuroendocrine Tumor

description: A pituitary neuroendocrine tumor that does not involve the sella turcica.


name: Acidophil Stem Cell Pituitary Neuroendocrine Tumor

description: An infrequent pituitary neuroendocrine tumor composed of cells showing immunoreactivity for prolactin and less often growth hormone. Electron microscopic studies reveal giant mitochondria, a finding not present in any other type of pituitary gland adenomas.


ACTH-producing pituitary gland adenoma

description: An adenoma of the pituitary gland that produces corticotropin. The vast majority of cases are associated with Cushing disease. Clinical manifestations include truncal obesity with thin extremities, thinning of the skin, osteoporosis, and a tendency to bruise easily. Silent or hormonally non-functioning ACTH producing adenomas have also been described. They produce symptoms of a mass-related lesion.


name: Non-Functioning Pituitary Neuroendocrine Tumor/Microadenoma

description: A pituitary neuroendocrine tumor/microadenoma not associated with a hormonal syndrome.


name: Pituitary Neuroendocrine Tumor of TPIT-Lineage

description: A pituitary neuroendocrine tumor arising from TPIT-lineage adenohypophysial cells.


name: Sparsely Granulated Somatotroph Pituitary Neuroendocrine Tumor

description: A growth hormone-producing pituitary neuroendocrine tumor composed of small, round cells containing fibrous bodies and scarce, small secretory granules.


name: Densely Granulated Lactotroph Pituitary Neuroendocrine Tumor

description: A rare prolactin-producing pituitary neuroendocrine tumor composed of acidophilic cells with many large secretory granules.  The endoplasmic reticulum is not as abundant as in the sparsely granulated subtype.


name: Sparsely Granulated Lactotroph Pituitary Neuroendocrine Tumor

description: A prolactin-producing pituitary neuroendocrine tumor composed of relatively large, chromophobic or slightly acidophilic cells with well developed, abundant endoplasmic reticulum, and many immature secretory granules.  Mature secretory granules are sparse.


name: Metastatic Unresectable Pituitary Neuroendocrine Tumor

description: Metastatic pituitary neuroendocrine tumor that is not amenable to surgical resection.


name: Plurihormonal Pituitary Neuroendocrine Tumor

description: A pituitary neuroendocrine tumor that expresses adenohypophyseal hormones and belongs to more than one adenohypophysial cell lineage.


name: Mature Plurihormonal PIT1 Lineage Pituitary Neuroendocrine Tumor

description: A well-differentiated pituitary neuroendocrine tumor composed of PIT1-lineage adenohypophyseal cells with acidophilic cytoplasm, extensive immunoreactivity for growth hormone and variable immunoreactivity for TSH, prolactin, and alpha-subunit. (WHO)


name: prolactin-producing pituitary gland adenoma

description: Prolactinoma is a usually benign neoplasm of the pituitary gland that results in hyperprolactinemia. The most common clinical manifestations are amenorrhea and infertility in women; and impotence, decreased libido and infertility in men.


name: Sparsely Granulated Corticotroph Pituitary Neuroendocrine Tumor

description: A corticotroph pituitary neuroendocrine tumor composed of faintly basophilic or chromophobic PAS-positive cells with weak or patchy positivity for ACTH, consistent with the scant, small secretory granules seen ultrastructurally. (WHO)


Atypical Pituitary Neuroendocrine Tumor

description: A usually aggressive and invasive pituitary neuroendocrine tumor characterized by excessive p53 immunoreactivity, increased mitotic activity, and MIB-1 proliferative index greater than 3%.


name: Densely Granulated Somatotroph Pituitary Neuroendocrine Tumor

description: A growth hormone-producing pituitary neuroendocrine tumor composed of medium-sized acidophilic cells with granular cytoplasm and abundant secretory granules.


description: A pituitary neuroendocrine tumor with a diameter equal or less than 10 mm.


name: Multiple Synchronous Pituitary Neuroendocrine Tumors of Distinct Lineages

description: Multiple pituitary neuroendocrine tumors composed of adenohypopheseal cells of two or more lineages or a null cell tumor in combination with a lineage-specific pituitary neuroendocrine tumor in the same gland.


name: Non-Functioning Sparsely Granulated Corticotroph Pituitary Neuroendocrine Tumor

description: A sparsely granulated corticotroph pituitary neuroendocrine tumor not associated with a hormonal syndrome.


name: Nasopharyngeal Pituitary Neuroendocrine Tumor

description: An ectopic pituitary neuroendocrine tumor that arises from the nasopharynx.


name: Mixed Gangliocytoma-Pituitary Neuroendocrine Tumor

description: A pituitary neoplasm composed of mature ganglionic cells admixed with pituitary neoplastic neuroendocrine cells.


name: ATP-binding cassette sub-family G member 1 isoform 4 (human)

description: An ATP-binding cassette sub-family G member 1 isoform 4 that is encoded in the genome of human.


name: ubiquitin-like domain-containing CTD phosphatase 1 isoform 1 (rat)

description: A ubiquitin-like domain-containing CTD phosphatase 1 isoform 1 that is encoded in the genome of rat.


name: ubiquitin-like domain-containing CTD phosphatase 1

description: A protein that is a translation product of the human UBLCP1 gene or a 1:1 ortholog thereof.


name: ubiquitin-like domain-containing CTD phosphatase 1 isoform 1 (human)

description: A ubiquitin-like domain-containing CTD phosphatase 1 isoform 1 that is encoded in the genome of human.


name: ubiquitin-like domain-containing CTD phosphatase 1 isoform m2 (mouse)

description: A ubiquitin-like domain-containing CTD phosphatase 1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8BGR9-2.


name: UBCP1_CHICK Ubiquitin-like domain-containing CTD phosphatase 1 (sprot)

description: A ubiquitin-like domain-containing CTD phosphatase 1 that is encoded in the genome of chicken.


name: UBCP1_DROME Ubiquitin-like domain-containing CTD phosphatase 1 (sprot)

description: A ubiquitin-like domain-containing CTD phosphatase 1 that is encoded in the genome of fruit fly.


name: UBCP1_HUMAN Ubiquitin-like domain-containing CTD phosphatase 1 (sprot)

description: A ubiquitin-like domain-containing CTD phosphatase 1 that is encoded in the genome of human.


name: ubiquitin-like domain-containing CTD phosphatase 1 isoform 1

description: A ubiquitin-like domain-containing CTD phosphatase 1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8WVY7-1 or a 1:1 ortholog thereof.


name: ubiquitin-like domain-containing CTD phosphatase 1 isoform 1 (mouse)

description: A ubiquitin-like domain-containing CTD phosphatase 1 isoform 1 that is encoded in the genome of mouse.


name: UBCP1_MOUSE Ubiquitin-like domain-containing CTD phosphatase 1 (sprot)

description: A ubiquitin-like domain-containing CTD phosphatase 1 that is encoded in the genome of mouse.


name: UBCP1_RAT Ubiquitin-like domain-containing CTD phosphatase 1 (sprot)

description: A ubiquitin-like domain-containing CTD phosphatase 1 that is encoded in the genome of rat.


name: ubiquitin-like domain-containing CTD phosphatase 1, initiator methionine removed form

description: A ubiquitin-like domain-containing CTD phosphatase 1 that has had the initiator methionine removed.


name: UBCP_ARATH Ubiquitin-like domain-containing CTD phosphatase (sprot)

description: A ubiquitin-like domain-containing CTD phosphatase 1 that is encoded in the genome of Arabidopsis thaliana.


name: ubiquitin-like domain-containing CTD phosphatase 1 isoform 1 (zebrafish)

description: A ubiquitin-like domain-containing CTD phosphatase 1 isoform 1 that is encoded in the genome of zebrafish.


name: ubiquitin-like domain-containing CTD phosphatase 1 isoform 1 (chicken)

description: A ubiquitin-like domain-containing CTD phosphatase 1 isoform 1 that is encoded in the genome of chicken.


name: THAP4_RAT Peroxynitrite isomerase THAP4 (sprot)

description: A peroxynitrite isomerase THAP4 that is encoded in the genome of rat.


name: receptor-type tyrosine-protein phosphatase dep-1 isoform a (worm)

description: A receptor-type tyrosine-protein phosphatase dep-1 (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:G5EGJ9-1.


tetraspanin-1 N-glycosylated 1 (human)

A tetraspanin-1 (human) that has been N-glycosylated at the residue equivalent to Asn-154 of the amino acid sequence represented by UniProtKB:O60635-1, in which the glycan composition is represented by GlyTouCan:G01650EU. Example: UniProtKB:O60635-1, Asn-154, MOD:00160~GNO:G01650EU.


TSN1_HUMAN Tetraspanin-1 (sprot)

A tetraspanin-1 that is encoded in the genome of human.


tetraspanin-1 isoform 1 (human)

A tetraspanin-1 isoform 1 that is encoded in the genome of human.


name: EI3EB_DANRE Eukaryotic translation initiation factor 3 subunit E-B (sprot)

description: A eukaryotic translation initiation factor 3 subunit E that is encoded in the genome of zebrafish.


name: eukaryotic translation initiation factor 3 subunit E-B isoform 2 (zebrafish)

description: A eukaryotic translation initiation factor 3 subunit E-B (zebrafish) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q1LUA8-2.


name: eukaryotic translation initiation factor 3 subunit E-B isoform 1 (zebrafish)

description: A eukaryotic translation initiation factor 3 subunit E-B (zebrafish) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q1LUA8-1.


name: follitropin subunit beta N-glycosylated 5 (human)

description: A follitropin subunit beta (human) that has been N-glycosylated at the residue equivalent to Asn-42 of the amino acid sequence represented by UniProtKB:P01225-1, in which the glycan structure is represented by GlyTouCan:G05850WN. Example: UniProtKB:P01225-1, Asn-42, MOD:00160~GNO:G05850WN.


name: unexplained long-lasting fever/inflammatory syndrome


name: vitamin K epoxide reductase complex subunit 1 isoform 1 (mouse)

description: A vitamin K epoxide reductase complex subunit 1 isoform 1 that is encoded in the genome of mouse.


name: LHX3_CHICK LIM/homeobox protein Lhx3 (sprot)

description: A LIM/homeobox protein Lhx3 that is encoded in the genome of chicken.


RHAA_ECOLI L-rhamnose isomerase (sprot)

An L-rhamnose isomerase that is encoded in the genome of Escherichia coli K-12.


L-rhamnose isomerase

A protein that is a translation product of the Escherichia coli K-12 rhaA gene or a 1:1 ortholog thereof.


name: transcription factor 7-like 2 isoform 1 (mouse)

description: A transcription factor 7-like 2 isoform 1 that is encoded in the genome of mouse.


name: tRNA (cytosine(38)-C(5))-methyltransferase isoform E (human)

description: A tRNA (cytosine(38)-C(5))-methyltransferase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O14717-5.


name: RHCL2_DANRE Ammonium transporter Rh type C-like 2 (sprot)

description: An ammonium transporter Rh type C that is encoded in the genome of zebrafish.


TMOD4_MOUSE Tropomodulin-4 (sprot)

A tropomodulin-4 that is encoded in the genome of mouse.


A protein that is a translation product of the human TMOD4 gene or a 1:1 ortholog thereof.


tropomodulin-4 isoform h2 (human)

A tropomodulin-4 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9NZQ9-2.


tropomodulin-4 isoform 1 (mouse)

A tropomodulin-4 isoform 1 that is encoded in the genome of mouse.


tropomodulin-4 isoform 1

A tropomodulin-4 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9NZQ9-1 or a 1:1 ortholog thereof.


TMOD4_HUMAN Tropomodulin-4 (sprot)

A tropomodulin-4 that is encoded in the genome of human.


tropomodulin-4 isoform 1 (human)

A tropomodulin-4 isoform 1 that is encoded in the genome of human.


name: polyglutamine-repeat protein pqn-41 isoform c (worm)

description: A polyglutamine-repeat protein pqn-41 (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:C7IVR4-3.


yadanziolide T

A quassinoid that is picras-3-ene substituted by hydroxy groups at positions 1, 11, 12, 15 and 21 and oxo groups at positions 2 and 16. Isolated from the ethanol extract of the stem of Brucea mollis, it exhibits cytotoxic activity.


An aromatic ether, being the (2R)-3-(tert-butylamino)-2-hydroxypropyl ether of the phenolic hydroxy group of (6S,7R)-5,6,7,8-tetrahydronaphthalene-1,6,7-triol.


Advanced Extramammary Paget Disease

description: Extramammary Paget disease that has spread extensively to other anatomic sites or is no longer responding to treatment.


extramammary Paget disease

description: A malignant neoplasm in which there is infiltration of the skin by neoplastic large cells with abundant pale cytoplasm and large nuclei with prominent nucleoli (Paget cells). It may affect the anus, penis, scrotum, and vulva.


vulval Paget disease

description: An uncommon intraepithelial malignant neoplasm of eccrine or apocrine origin, arising from the vulva. It usually affects post-menopausal women. In approximately 10-20% of the cases there is an associated anorectal, or urothelial carcinoma or a skin appendage adenocarcinoma identified. It presents as a red, eczematous lesion. Microscopically, it is characterized by the presence of the typical Paget cells which are large, round cells with abundant cytoplasm and prominent nuclei.


scrotum Paget disease

description: A mammary Paget's disease that involves the scrotum.


name: Recurrent Paget Disease of the Anal Canal

description: The reemergence of Paget disease of the anal canal after a period of remission.


Recurrent Extramammary Paget Disease

description: The reemergence of extramammary Paget disease after a period of remission.


Metastatic Extramammary Paget Disease

description: Extramammary Paget disease that has spread from the original site of growth to other anatomic sites.


Paget disease of the penis

description: A premalignant condition morphologically characterized by the presence of the characteristic Paget cells in the intraepithelial tissue of the penis. It presents as a smooth raised reddish area that may or may not be painful. -- 2003


Refractory Extramammary Paget Disease

description: Extramammary Paget disease that is resistant to treatment.


name: sorbin and SH3 domain-containing protein 2 isoform m6 (mouse)

description: A sorbin and SH3 domain-containing protein 2 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q3UTJ2-6.


name: DnaJ homolog subfamily A member 1 cysteinylated 2 (human)

description: A DnaJ homolog subfamily A member 1 (human) that has been cysteinylated on the residue at the position equivalent to Cys-177 of the amino acid sequence represented by UniProtKB:P31689-1. Example: UniProtKB:P31689-1, Cys-177, MOD:00765.


cullin-4A isoform h2 (human)

A cullin-4A (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q13619-2.


name: tyrosine-protein kinase SYK cysteinylated 1 (human)

description: A tyrosine-protein kinase SYK (human) that has been cysteinylated on the residue at the position equivalent to Cys-608 of the amino acid sequence represented by UniProtKB:P43405-1. Example: UniProtKB:P43405-1, Cys-608, MOD:00765.


name: tyrosine-protein kinase SYK isoform Short (human)

description: A tyrosine-protein kinase SYK (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P43405-2.


name: tyrosine-protein kinase SYK deaminated 1 (human)

description: A tyrosine-protein kinase SYK (human) that has been deaminated on the residue at the position equivalent to Asn-499 of the amino acid sequence represented by UniProtKB:P43405-1. Example: UniProtKB:P43405-1, Asn-499, MOD:00684.


name: tyrosine-protein kinase SYK phosphotyrosine form (human)

description: A tyrosine-protein kinase SYK (human) that includes at least one phosphorylated tyrosine. UniProtKB:P43405, MOD:00048.


name: tyrosine-protein kinase SYK phosphorylated 2 (human)

description: A tyrosine-protein kinase SYK phosphorylated 2 in human. UniProtKB:P43405, Tyr-348, MOD:00048.


name: tyrosine-protein kinase SYK phosphorylated 3 (human)

description: A tyrosine-protein kinase SYK (human) that has been post-translationally modified to include phosphotyrosine at positions 131, 323, 348, 352, 525 and 526 of the amino acid sequence represented by UniProtKB:P43405. UniProtKB:P43405, Tyr-131/Tyr-323/Tyr-348/Tyr-352/Tyr-525/Tyr-526, MOD:00048.


name: collagen alpha-1(XXIII) chain 4-hydroxy-proline and galactosylhydroxylysine form (human)

description: A collagen alpha-1(XXIII) chain (human) that includes at least 1 galactosylhydroxylated lysine and at least 3 4-hydroxy-prolines. UniProtKB:Q86Y22, MOD:00039(3+)|MOD:01914.


name: mitogen-activated protein kinase kinase kinase 20 methylated 2 (human)

description: A mitogen-activated protein kinase kinase kinase 20 (human) that has been methylated on the residue at the position equivalent to Arg-670 of the amino acid sequence represented by UniProtKB:Q9NYL2-1. Example: UniProtKB:Q9NYL2-1, Arg-670, MOD:00658.


name: chorion-specific transcription factor GCMa isoform 1

description: A chorion-specific transcription factor GCMa that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9NP62-1 or a 1:1 ortholog thereof.


name: chorion-specific transcription factor GCMa

description: A protein that is a translation product of the human GCM1 gene or a 1:1 ortholog thereof.


name: chorion-specific transcription factor GCMa acetylated 1

description: A chorion-specific transcription factor GCMa that has been acetylated in Lys residues within the C-terminal region. Example: UniProtKB:P70348, Lys-367/Lys-406, MOD:00064.


name: chorion-specific transcription factor GCMa acetylated 1 (mouse)

description: A chorion-specific transcription factor GCMa acetylated 1 in mouse. UniProtKB:P70348, Lys-367/Lys-406, MOD:00064.


name: chorion-specific transcription factor GCMa isoform 1 (human)

description: A chorion-specific transcription factor GCMa isoform 1 that is encoded in the genome of human.


name: GCM1_HUMAN Chorion-specific transcription factor GCMa (sprot)

description: A chorion-specific transcription factor GCMa that is encoded in the genome of human.


name: GCM1_RAT Chorion-specific transcription factor GCMa (sprot)

description: A chorion-specific transcription factor GCMa that is encoded in the genome of rat.


name: GCM1_MOUSE Chorion-specific transcription factor GCMa (sprot)

description: A chorion-specific transcription factor GCMa that is encoded in the genome of mouse.


name: chorion-specific transcription factor GCMa isoform 1 acetylated 1

description: A chorion-specific transcription factor GCMa isoform 1 that has been acetylated on Lys residues located within the transactivation domain (TAD) towards the C-terminus. Example: UniProtKB:Q9NP62-1, Lys-367/Lys-406/Lys-409, MOD:00064.


name: chorion-specific transcription factor GCMa isoform 1 acetylated 1 (human)

description: A chorion-specific transcription factor GCMa isoform 1 acetylated 1 in human. UniProtKB:Q9NP62-1, Lys-367/Lys-406/Lys-409, MOD:00064.


name: TDCR_ECOLI Threonine dehydratase operon activator protein (sprot)

description: A threonine dehydratase operon activator protein that is encoded in the genome of Escherichia coli K-12.


name: bromodomain adjacent to zinc finger domain protein 2B deaminated 2 (human)

description: A bromodomain adjacent to zinc finger domain protein 2B (human) that has been deaminated on the residue at the position equivalent to Gln-499 of the amino acid sequence represented by UniProtKB:Q9UIF8-1. Example: UniProtKB:Q9UIF8-1, Gln-499, MOD:00685.


name: bromodomain adjacent to zinc finger domain protein 2B

description: A protein that is a translation product of the human BAZ2B gene or a 1:1 ortholog thereof.


name: BAZ2B_MOUSE Bromodomain adjacent to zinc finger domain protein 2B (sprot)

description: A bromodomain adjacent to zinc finger domain protein 2B that is encoded in the genome of mouse.


name: bromodomain adjacent to zinc finger domain protein 2B isoform h5 (human)

description: A bromodomain adjacent to zinc finger domain protein 2B (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9UIF8-5.


name: bromodomain adjacent to zinc finger domain protein 2B isoform h2 (human)

description: A bromodomain adjacent to zinc finger domain protein 2B (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9UIF8-2.


name: bromodomain adjacent to zinc finger domain protein 2B isoform m2 (mouse)

description: A bromodomain adjacent to zinc finger domain protein 2B (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:A2AUY4-2.


name: BAZ2B_CHICK Bromodomain adjacent to zinc finger domain protein 2B (sprot)

description: A bromodomain adjacent to zinc finger domain protein 2B that is encoded in the genome of chicken.


name: bromodomain adjacent to zinc finger domain protein 2B isoform h4 (human)

description: A bromodomain adjacent to zinc finger domain protein 2B (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9UIF8-4.


name: bromodomain adjacent to zinc finger domain protein 2B isoform h1 (human)

description: A bromodomain adjacent to zinc finger domain protein 2B (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9UIF8-1.


name: bromodomain adjacent to zinc finger domain protein 2B isoform m1 (mouse)

description: A bromodomain adjacent to zinc finger domain protein 2B (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:A2AUY4-1.


name: bromodomain adjacent to zinc finger domain protein 2B isoform h3 (human)

description: A bromodomain adjacent to zinc finger domain protein 2B (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9UIF8-3.


name: BAZ2B_HUMAN Bromodomain adjacent to zinc finger domain protein 2B (sprot)

description: A bromodomain adjacent to zinc finger domain protein 2B that is encoded in the genome of human.


name: bromodomain adjacent to zinc finger domain protein 2B deaminated 1 (human)

description: A bromodomain adjacent to zinc finger domain protein 2B (human) that has been deaminated on the residue at the position equivalent to Gln-1048 of the amino acid sequence represented by UniProtKB:Q9UIF8-1. Example: UniProtKB:Q9UIF8-1, Gln-1048, MOD:00685.


name: microtubule-associated protein 2 isoform r1 (rat)

description: A microtubule-associated protein 2 (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P15146-1.


name: non-specific lipid transfer protein GPI-anchored 29 isoform 2 (Arabidopsis thaliana)

description: A non-specific lipid transfer protein GPI-anchored 29 (Arabidopsis thaliana) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9FY78-2.


name: LTG29_ARATH Non-specific lipid transfer protein GPI-anchored 29 (sprot)

description: A protein that is a translation product of the LTPG29 gene in Arabidopsis thaliana.


name: non-specific lipid transfer protein GPI-anchored 29 isoform 1 (Arabidopsis thaliana)

description: A non-specific lipid transfer protein GPI-anchored 29 (Arabidopsis thaliana) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9FY78-1.


polycystin-1 isoform h2 (human)

A polycystin-1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P98161-2.