name: Retromolar Trigone Squamous Cell Carcinoma

description: A squamous cell carcinoma that arises from the retromolar trigone. Pain, often radiating to the ear, is the presenting symptom. The prognosis is poor.


A branched amino nonasaccharide consisting of a beta-D-GlcNAc residue at the reducing end with a beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)]-[beta-D-Xyl-(1->2)]-beta-D-Man-(1->4)-beta-D-GlcNAc moiety attached via a beta-(1->4)-linkage and an alpha-L-Fuc residue attached via an alpha-(1->6)-linkage.


9'-hydroxyabscisic acid

An  oxo monocarboxylic acid that is (+)-abscisic acid substituted by a hydroxy group at position 9'.


name: Paranasal sinus teratocarcinosarcoma (type)

category: biolink:Disease biolink:DiseaseOrPhenotypicFeature biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing

description: A malignant sinonasal neoplasm with combined histological features of teratoma and carcinosarcoma, lacking malignant germ cell components. (WHO 2017)


carcinosarcoma of salivary gland

description: An aggressive, high grade malignant tumor that arises from the salivary gland. It is characterized by the presence of a malignant epithelial and a sarcomatous component.


Lacrimal Gland Carcinosarcoma

description: An aggressive, high grade malignant neoplasm that arises from the lacrimal gland. It is characterized by the presence of a malignant epithelial and a sarcomatous component.


Pleomorphic adenoma of parotid gland

description: A benign, slow-growing tumor that arises from the parotid gland.  It is composed of cells that demonstrate both epithelial and mesenchymal differentiation. It is the most common neoplasm of salivary gland origin and women are more often affected than men.


name: Recurrent Childhood Anaplastic Oligoastrocytoma

description: The reemergence of anaplastic oligoastrocytoma in childhood after a period of remission.


name: Malignant Mixed Tumor of the Major Salivary Gland

description: A malignant tumor arising from the parotid gland, submandibular gland, or sublingual gland.  It includes carcinoma ex pleomorphic adenoma, a malignant epithelial tumor arising from a pre-existing pleomorphic adenoma and carcinosarcoma which is characterized by a mixture of malignant epithelial and sarcomatous elements.


Conjunctival Adenosquamous Carcinoma

description: A carcinoma that arises from the conjunctiva. It is characterized by the presence of a variable combination of squamous (epidermoid) cells and mucous cells, arranged in invasive sheets, cords, and ducts. (WHO 2018)


name: Stage III Uterine Corpus Adenosarcoma AJCC v8

description: Stage III includes: IIIA: T3a, N0, M0; IIIB: T3b, N0, M0; IIIC: T1-3, N1, M0. T1: Uterine corpus adenosarcoma with tumor limited to the uterus. T2: Uterine corpus adenosarcoma with tumor extending beyond the uterus, within the pelvis. T3: Uterine corpus adenosarcoma with tumor infiltrating abdominal tissues. T3a: Uterine corpus adenosarcoma with tumor infiltrating abdominal tissues at one site. T3b: Uterine corpus adenosarcoma with tumor infiltrating abdominal tissues at more than one site. N0: No regional lymph node metastasis. N1: Regional lymph node metastasis. M0: No distant metastasis. (AJCC 8th Ed.)


name: Adenocarcinoma with cartilaginous and osseous metaplasia

description: An invasive adenocarcinoma characterized by focal or extensive cartilage and/or bone formation.


Recurrent Anaplastic Oligoastrocytoma

description: The reemergence of anaplastic oligoastrocytoma after a period of remission.


Uterine Carcinosarcoma, Homologous Type

description: A carcinosarcoma of the uterus characterized by the presence of sarcomatous elements that arise from the tissues of the uterus.


name: Uterine Corpus Adenosarcoma by AJCC v8 Stage

description: A term that refers to the staging of uterine corpus adenosarcoma according to the American Joint Committee on Cancer, 8th edition.


name: Testicular Mixed Embryonal Carcinoma and Teratoma with Seminoma

description: A malignant mixed germ cell tumor arising from the testis.  It is characterized by the presence of a mixture of embryonal carcinoma, a teratomatous component, and a seminomatous component.


name: Metastatic Endometrial Adenosquamous Carcinoma

description: Endometrial adenosquamous carcinoma that has spread from its original site of growth to another anatomic site.


name: mixed acinar-endocrine carcinoma of pancreas

description: A carcinoma that arises from the pancreas and is composed of acinar carcinoma and neuroendocrine carcinoma components in both the primary tumor and the metastatic sites.


name: Benign Cervical Mixed Epithelial and Mesenchymal Neoplasm

description: A neoplasm that arises from the cervix and is characterized by the presence of benign epithelial and benign mesenchymal elements. This category includes adenofibroma and adenomyoma.


Primary peritoneal carcinosarcoma

description: An extremely rare and highly aggressive malignant neoplasm arising from the peritoneum.  Morphologically, it is a high grade tumor, composed of carcinomatous and sarcomatous elements.


Hybrid Salivary Gland Tumor

description: A rare neoplasm that arises from the salivary gland and consists of at least two histologically distinct types of tumor within the same topographic location. The tumor components can be either benign or malignant.


name: Uterine Carcinosarcoma, Heterologous Type

description: A carcinosarcoma of the uterus characterized by the presence of sarcomatous elements composed of tissues that are not found in the uterus (e.g., bone, cartilage, skeletal muscle).


name: Appendix Mixed Adenoneuroendocrine Carcinoma

description: A carcinoma that arises from the appendix.  It is characterized by the presence of a malignant glandular epithelial component and a malignant neuroendocrine component.  At least 30 percent of either component should be present for the diagnosis to be made.


name: Metastasizing Pleomorphic Adenoma of the Salivary Gland

description: A very rare pleomorphic adenoma of the salivary glands that metastasizes inexplicably, despite the benign histopathologic features.  The most common sites of metastasis are bone, lung, and head and neck.


Oropharyngeal Pleomorphic Adenoma

description: A pleomorphic adenoma that arises from the oropharynx.


name: Stage IIIA Uterine Corpus Adenosarcoma AJCC v8

description: Stage IIIA includes: T3a, N0, M0. T3a: Uterine corpus adenosarcoma with tumor infiltrating abdominal tissues at one site. N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 8th Ed.)


Borderline Serous Cystadenofibroma

description: A neoplasm of low malignant potential arising from a site in the female reproductive system. Almost all cases have been reported in the ovary. It is characterized by the presence of cystic spaces which are lined by atypical serous epithelial cells. The surrounding ovarian stroma is fibrotic. There is no evidence of stromal invasion.


Advanced Uterine Corpus Carcinosarcoma

description: Uterine corpus carcinosarcoma that has spread extensively to other anatomic sites or is no longer responding to treatment.


name: Stage IIIC Uterine Corpus Adenosarcoma AJCC v8

description: Stage IIIC includes: T1-3, N1, M0. T1: Uterine corpus adenosarcoma with tumor limited to the uterus. T2: Uterine corpus adenosarcoma with tumor extending beyond the uterus, within the pelvis. T3: Uterine corpus adenosarcoma with tumor infiltrating abdominal tissues. N1: Regional lymph node metastasis. M0: No distant metastasis. (AJCC 8th Ed.)


name: Advanced Malignant Mixed Mesodermal (Mullerian) Tumor

description: A malignant mixed mesodermal (Mullerian) tumor that has spread extensively to other anatomic sites or is no longer responding to treatment.


name: Stage I Uterine Corpus Adenosarcoma AJCC v8

description: Stage I includes: T1, N0, M0. T1: Uterine corpus adenosarcoma with tumor limited to the uterus. N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 8th Ed.)


name: Metastatic Cervical Adenosquamous Carcinoma

description: A cervical adenosquamous carcinoma that has spread to another anatomic site.


name: Testicular Mixed Choriocarcinoma and Seminoma

description: A malignant germ cell tumor arising from the testis.  It is characterized by a mixture of choriocarcinoma and seminomatous morphologic elements.  Patients may present with painless or painful testicular swelling.


name: Metastatic Pancreatic Adenosquamous Carcinoma

description: Pancreatic adenosquamous carcinoma that has spread from its original site of growth to another anatomic site.


name: Skin Squamous Cell Carcinoma with Sarcomatoid Differentiation

description: A rare carcinoma of the skin characterized by the presence of squamous cell carcinomatous and sarcomatous components.


Sellar Mixed Germ Cell Tumor

description: A mixed germ cell tumor that arises from or adjacent to the sellar region.


Cellular Pleomorphic Adenoma

description: A pleomorphic adenoma with increased cellularity.


name: Metastatic Vaginal Adenosquamous Carcinoma

description: Vaginal adenosquamous carcinoma that has spread from its original site of growth to another anatomic site.


name: Anal Canal Mixed Adenoneuroendocrine Carcinoma

description: A carcinoma that arises from the anal canal.  It is characterized by the presence of a malignant glandular epithelial component and a malignant neuroendocrine component.  At least 30 percent of either component should be present for the diagnosis to be made.


Recurrent Childhood Oligoastrocytoma

description: The reemergence of oligoastrocytoma in childhood after a period of remission.


Hard Palate Pleomorphic Adenoma

description: A benign, slow-growing and painless neoplasm that arises from the minor salivary glands in the hard palate.  It is composed of cells that demonstrate both epithelial and mesenchymal differentiation.


carcinosarcoma of gallbladder

description: A carcinoma that arises from the gallbladder and it is characterized by the presence of a sarcomatous component.  The sarcomatous component may contain osteosarcoma, chondrosarcoma, or rhabdomyosarcoma elements.


name: Mixed neuroendocrine-non neuroendocrine neoplasm

description: A rare neoplasm that consists of neuroendocrine and non-neuroendocrine cellular components. At least 30% of either component should be present for the diagnosis to be made.


name: Metastatic Uterine Corpus Carcinosarcoma

description: Uterine corpus carcinosarcoma that has spread from its original site of growth to another anatomic site.


name: Pancreatic Mixed Ductal Adenocarcinoma-Neuroendocrine Tumor

description: A very rare mixed neuroendocrine non-neuroendocrine neoplasm that arises from the pancreas and is composed of ductal adenocarcinoma and a neuroendocrine tumor component.


name: Testicular Mixed Embryonal Carcinoma and Teratoma

description: A malignant mixed germ cell tumor arising from the testis, characterized by the presence of an embryonal carcinomatous component and a teratomatous component.


name: Gallbladder Mixed Adenoneuroendocrine Carcinoma

description: A carcinoma that arises from the gallbladder and is characterized by the presence of a malignant glandular epithelial component and a malignant neuroendocrine component.  At least 30 percent of either component should be present for the diagnosis to be made.


Sinonasal Pleomorphic Adenoma

description: A pleomorphic adenoma that arises from the sinonasal tract.


Metastatic Carcinosarcoma

description: Carcinosarcoma that has spread from its original site of growth to another anatomic site.


Recurrent Fallopian Tube Carcinosarcoma

description: The reemergence of fallopian tube carcinosarcoma after a period of remission.


Hybrid Salivary Gland Carcinoma

description: A rare carcinoma that arises from the salivary gland and consists of at least two histologically distinct types of carcinoma within the same topographic location. The carcinoma components usually are adenoid cystic carcinoma, epithelial-myoepithelial carcinoma, and/or salivary duct carcinoma. Adenoid cystic carcinoma is commonly the predominant component.


Adult Mixed Glioma

description: A mixed glioma that occurs during adulthood.


Malignant chondroid syringoma

description: A rare malignant skin neoplasm that arises from a benign mixed tumor of the skin (chondroid syringoma).


Uterine Ligament Adenomyoma

description: A benign neoplasm that arises from the broad or other uterine ligaments. It is characterized by the presence of a glandular and a mesenchymal component.


name: Testicular Mixed Choriocarcinoma and Embryonal Carcinoma

description: A malignant mixed germ cell tumor that arises from the testis and is characterized by the presence of choriocarcinoma and embryonal carcinoma morphologic components.


name: Stage IIIB Uterine Corpus Adenosarcoma AJCC v8

description: Stage IIIB includes: T3b, N0, M0. T3b: Uterine corpus adenosarcoma with tumor infiltrating abdominal tissues at more than one site. N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 8th Ed.)


Mixed parotid tumor

description: A benign or malignant neoplasm that arises from the parotid gland.  It is characterized by the presence of epithelial and mesenchymal elements.  This category includes pleomorphic adenoma, carcinoma ex pleomorphic adenoma, and carcinosarcoma.


name: Testicular Mixed Teratoma and Yolk Sac Tumor, Prepubertal-Type

description: A very rare testicular germ cell tumor that combines teratoma and yolk sac tumor. It usually affects young children. It is not associated with chromosome 12p amplification or germ cell neoplasia in situ.


Childhood Oligoastrocytoma

description: An oligoastrocytoma that occurs during childhood.


name: Gastric Mixed Adenoneuroendocrine Carcinoma

description: A carcinoma that arises from the stomach and is characterized by the presence of a malignant glandular epithelial component and a malignant neuroendocrine component.  At least 30 percent of either component should be present for the diagnosis to be made.


name: Minor Salivary Gland Carcinoma ex Pleomorphic Adenoma

description: A carcinoma that arises from a pleomorphic adenoma in the minor salivary glands.  Patients usually present with a history of a long-standing tumor mass which grew rapidly in the past few months.  Patients with non-invasive or minimally invasive carcinoma have an excellent prognosis.  In cases where there is invasion of the surrounding tissues, the clinical course is aggressive.


Oral Cavity Pleomorphic Adenoma

description: A benign, slow-growing and painless neoplasm that arises from the salivary glands in the oral cavity.  It is composed of cells that demonstrate both epithelial and mesenchymal differentiation.


name: Stage IA Uterine Corpus Adenosarcoma AJCC v8

description: Stage IA includes: T1a, N0, M0. T1a: Uterine corpus adenosarcoma with tumor limited to the endometrium/endocervix. N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 8th Ed.)


name: Testicular Mixed Choriocarcinoma and Yolk Sac Tumor

description: A malignant germ cell tumor arising from the testis.  It is characterized by a mixture of choriocarcinoma and yolk sac tumor morphologic elements.  Patients may present with painless or painful testicular swelling.


Recurrent Oligoastrocytoma

description: The reemergence of oligoastrocytoma after a period of remission.


name: Pancreatic Mixed Ductal-Neuroendocrine Neoplasm

description: A rare mixed neuroendocrine non-neuroendocrine neoplasm that arises from the pancreas and is composed of ductal adenocarcinoma and a neuroendocrine neoplastic component. The latter is usually a poorly differentiated neuroendocrine carcinoma and rarely a well differentiated neuroendocrine tumor.


name: Testicular Mixed Yolk Sac Tumor and Teratoma

description: A malignant non-seminomatous germ cell tumor arising from the testis.  It is characterized by a mixture of yolk sac and teratomatous morphologic elements.  Patients may present with painless or painful testicular swelling.


name: Malignant Submandibular Gland Mixed Tumor

description: A malignant tumor arising from the submandibular gland.  It includes carcinoma ex pleomorphic adenoma, a malignant epithelial tumor arising from a pre-existing pleomorphic adenoma and carcinosarcoma which is characterized by a mixture of malignant epithelial and sarcomatous elements.


name: Benign Uterine Corpus Mixed Epithelial and Mesenchymal Neoplasm

description: A non-metastasizing neoplasm that arises from the uterine corpus and is composed of epithelial and mesenchymal elements. Representative examples include adenomyoma and adenofibroma.


name: Testicular Mixed Yolk Sac Tumor and Teratoma with Seminoma

description: A malignant germ cell tumor arising from the testis.  It is characterized by a mixture of yolk sac, teratomatous, and seminomatous morphologic elements.  Patients may present with painless or painful testicular swelling.


Mixed Carcinoma

description: A carcinoma characterized by the presence of more than one malignant epithelial histologic pattern.


name: Stage IVB Uterine Corpus Adenosarcoma AJCC v8

description: Stage IVB includes: Any T, Any N, M1. M1: M1: Distant metastasis (excluding adnexa, pelvic, and abdominal tissues). (from AJCC 8th Ed.)


name: Recurrent Cervical Adenosquamous Carcinoma

description: The reemergence of cervical adenosquamous carcinoma after a period of remission.


name: Stage IB Uterine Corpus Adenosarcoma AJCC v8

description: Stage IB includes: T1b, N0, M0. T1b: Uterine corpus adenosarcoma with tumor invading to less than half of the myometrium. N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 8th Ed.)


name: Recurrent Primary Peritoneal Carcinosarcoma

description: The reemergence of primary peritoneal carcinosarcoma after a period of remission.


name: Malignant Mixed Tumor, Not Otherwise Specified

description: A malignant myoepithelioma characterized by the presence of a minor ductal component.


Childhood Anaplastic Oligoastrocytoma

description: An anaplastic oligoastrocytoma that occurs during childhood.


Childhood Breast Fibroadenoma

description: A fibroadenoma that arises from the breast and occurs during childhood.


name: Ampulla of Vater Mixed Adenoneuroendocrine Carcinoma

description: A carcinoma that arises from the ampulla of Vater and the periampullary region. It is characterized by the presence of a malignant glandular epithelial component and a malignant neuroendocrine component.  At least 30 percent of either component should be present for the diagnosis to be made.


Childhood Mixed Glioma

description: A mixed glioma that occurs during childhood.


name: Stage II Uterine Corpus Adenosarcoma AJCC v8

description: Stage II includes: T2, N0, M0. T2: Uterine corpus adenosarcoma with tumor extending beyond the uterus, within the pelvis. N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 8th Ed.)


adenosquamous carcinoma of tongue

description: A rare adenosquamous carcinoma that arises from the tongue.


name: Testicular Mixed Embryonal Carcinoma and Seminoma

description: A malignant mixed germ cell tumor arising from the testis.  It is characterized by the presence of a mixture of embryonal carcinoma and a seminomatous component.


name: Refractory Uterine Corpus Carcinosarcoma

description: Uterine Corpus Carcinosarcoma that is resistant to treatment.


Advanced Carcinosarcoma

description: Carcinosarcoma that has spread extensively to other anatomic sites or is no longer responding to treatment.


name: Choriocarcinoma combined with other germ cell elements

description: A malignant mixed germ cell tumor characterized by the presence of a choriocarcinomatous component admixed with another germ cell component (e.g. embryonal carcinoma, teratoma, or seminoma).


name: Recurrent Endometrial Adenosquamous Carcinoma

description: The reemergence of endometrial adenosquamous carcinoma after a period of remission.


name: Malignant Vaginal Mixed Tumor Resembling Synovial Sarcoma

description: A very rare malignant mixed epithelial and mesenchymal neoplasm that arises from the vagina and resembles synovial sarcoma.  It is characterized by a biphasic pattern and is composed of gland-like structures that are lined by epithelial cells and a cellular mesenchymal component.


Malignant Parotid Gland Mixed Tumor

description: A malignant tumor arising from the parotid gland.  It includes carcinoma ex pleomorphic adenoma, a malignant epithelial tumor arising from a pre-existing pleomorphic adenoma and carcinosarcoma which is characterized by a mixture of malignant epithelial and sarcomatous elements.


Odontogenic Carcinosarcoma

description: An extremely rare malignant mixed odontogenic neoplasm in which both the epithelial and the mesenchymal components are cytologically malignant. (WHO 2017)


name: Advanced Pancreatic Adenosquamous Carcinoma

description: Pancreatic adenosquamous carcinoma that has spread extensively to other anatomic sites or is no longer responding to treatment.


Invasive Bladder Mixed Carcinoma

description: An invasive bladder carcinoma characterized by the presence of more than one histologic pattern.


name: Human Papillomavirus-Related Adenosquamous Carcinoma

description: An adenosquamous carcinoma associated with the presence of human papillomavirus infection.


name: Esophageal Mixed Adenoneuroendocrine Carcinoma

description: A carcinoma that arises from the esophagus and is characterized by the presence of a malignant glandular epithelial component and a malignant neuroendocrine component.  At least 30 percent of either component should be present for the diagnosis to be made.


Vaginal Adenosquamous Carcinoma

description: A carcinoma that arises from the vagina and is characterized by the presence of malignant glandular and malignant squamous epithelial components.


Laryngeal Pleomorphic Adenoma

description: A very rare pleomorphic adenoma that arises from the larynx.


name: Stage IVA Uterine Corpus Adenosarcoma AJCC v8

description: Stage IVA includes: T4, Any N, M0. T4: Uterine corpus adenosarcoma with tumor invading bladder or rectum. M0: No distant metastasis. (from AJCC 8th Ed.)


Mixed Tumor, Not Otherwise Specified

description: A benign myoepithelioma characterized by the presence of a minor ductal component.


name: Vulvar Composite Hidradenoma Papilliferum and Fibroadenoma

description: A benign composite neoplasm that arises from the vulva and is characterized by mixed histopathologic features of hidradenoma papilliferum and fibroadenoma.


name: Testicular Mixed Embryonal Carcinoma and Yolk Sac Tumor

description: A malignant non-seminomatous germ cell tumor arising from the testis.  It is characterized by a mixture of embryonal carcinoma and yolk sac morphologic elements.  Patients may present with painless or painful testicular swelling.


name: Pancreatic Mixed Acinar-Ductal Neuroendocrine Carcinoma

description: A very rare carcinoma that arises from the pancreas and is composed of ductal adenocarcinoma, acinar carcinoma, and neuroendocrine carcinoma components.


Trichoblastic carcinosarcoma

description: A rare biphasic follicular neoplasm consisting of a malignant epithelial component resembling follicular germinative cells closely associated with a malignant stromal component differentiating towards specific follicular mesenchyme. (WHO 2018)


name: Metastatic Digestive System Mixed Adenoneuroendocrine Carcinoma

description: Mixed adenoneuroendocrine carcinoma that arises from the digestive system and has metastasized to other anatomic sites.


Hybrid nerve sheath tumor

description: A benign nerve sheath tumor characterized by the combination of histologic features seen in schwannomas, neurofibromas, and perineuriomas.


Pleomorphic adenoma of lacrimal gland

description: A benign, usually encapsulated neoplasm of the lacrimal gland composed of epithelial and mesenchymal cells.  Pleomorphic adenomas are neoplasms that develop in the salivary glands or heterotopic salivary gland tissues.  It has been suggested that myoepithelial cells play a major role in the histogenesis of these tumors.  In the lacrimal gland, pleomorphic adenomas presumably develop from metaplastic myoepithelial cells.


name: Malignant Mixed Tumor of the Minor Salivary Gland

description: A malignant tumor arising from the minor salivary glands.  It includes carcinoma ex pleomorphic adenoma, a malignant epithelial tumor arising from a pre-existing pleomorphic adenoma and carcinosarcoma which is characterized by a mixture of malignant epithelial and sarcomatous elements.


name: Seminal Vesicle Mixed Epithelial and Stromal Tumor

description: A rare biphasic neoplasm that arises from the seminal vesicle. It is characterized by the presence of stromal and benign epithelial components. Rarely, the stromal component may display atypia and mitotic activity and the tumor may behave in a malignant clinical course.


Soft Palate Pleomorphic Adenoma

description: A benign, slow-growing and painless neoplasm that arises from the minor salivary glands in the soft palate.  It is composed of cells that demonstrate both epithelial and mesenchymal differentiation.


Breast Pleomorphic Adenoma

description: A rare, benign and well circumscribed neoplasm that arises from the breast.  It is characterized by the proliferation of epithelial and myoepithelial cells surrounded by chondroid stroma.


name: Stage IC Uterine Corpus Adenosarcoma AJCC v8

description: Stage IC includes: T1c, N0, M0. T1c: Uterine corpus adenosarcoma with tumor invading more than half of the myometrium. N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 8th Ed.)


name: Stage IV Uterine Corpus Adenosarcoma AJCC v8

description: Stage IV includes: IVA: T4, Any N, M0; IVB: Any T, Any N, M1. T4: Uterine corpus adenosarcoma with tumor invading bladder or rectum. M0: No distant metastasis. M1: Distant metastasis (excluding adnexa, pelvic, and abdominal tissues). (from AJCC 8th Ed.)


name: Metastatic Malignant Mixed Mesodermal (Mullerian) Tumor

description: A malignant mixed mesodermal (Mullerian) tumor that has spread from its original site of growth to another anatomic site.


Recurrent Uterine Corpus Carcinosarcoma

description: The reemergence of uterine corpus carcinosarcoma after a period of remission.


Parotid Gland Carcinosarcoma

description: An aggressive, high grade malignant tumor that arises from the parotid gland. It is characterized by the presence of a malignant epithelial and a sarcomatous component.


distigmine

A carbamate ester resulting from the formal condensation of both carboxy groups of hexane-1,6-diylbis(methylcarbamic acid) with the hydroxy group of 3-hydroxy-1-methylpyridinium.


name: Gallbladder Mucinous Cystic Neoplasm, High Grade

description: A non-invasive mucinous cystic neoplasm that arises from the gallbladder epithelium.  It is characterized by the presence of severe atypia.


name: Adenocarcinoma of anogenital mammary-like glands

description: A primary invasive malignant epithelial neoplasm of the vulva showing morphological features of recognized breast adenocarcinomas. (WHO, 2014)


Vulvar Adenocarcinoma, Intestinal-Type

description: A rare vulvar mucinous adenocarcinoma that resembles a large intestinal adenocarcinoma.


name: 4-(dimethylamino)benzoic acid [2-(2-methoxyphenyl)-2-oxoethyl] ester


curacozole

An azamacrocycle obtained from a core peptide of sequence Phe-Ile-Ile-Gly-Ser-Thr-Cys-Cys encoded in the genome of several Streptomyces species. It exhibits potent cytotoxic activity against HCT116 and HOS cancer cells.


A chlorocatechol that is catechol which is substituted by a methyl group at position 3 and a chlorine at position 4.


name: 2-(5-methyl-3-oxo-1H-pyrazol-2-yl)-6-oxo-1H-pyrimidine-5-carboxylic acid ethyl ester


name: 3-hydroxy-2-phenylpropanoic acid [(5R)-8-methyl-8-propan-2-yl-8-azoniabicyclo[3.2.1]octan-3-yl] ester


pseudopelletierine

An azabicycloalkane alkaloid that is 9-azabicyclo[3.3.1]nonane substituted by a methyl group at position 9 and an oxo group at position 3. It is found in pomegranate trees.


biotinylated alpha-gal

Biotin linked to the alpha-gal epitope through a 6-amino-N-(3-hydroxypropyl)hexanamide spacer.


ecgonine methyl ester

The O-debenzoyl analogue of cocaine.


name: (2S)-3-hydroxy-2-phenylpropanoic acid [(1R,5R)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] ester


A member of the class of azabicycloalkanes that is 1,3-diazabicyclo[2.2.0]hex-4-en-2-one substituted at position 6 by a 5-amino-5-methyl-2,4-dioxodihydropyrimidin-6-yl group.


A disaccharide derivative in which alpha-D-galactosaminyl-(1->4)-alpha-D-galactosamine is linked glycosidically to biotin via a (21-oxo-3,6,9,12,15,18-hexaoxa-22-azapentacosan-1-yl)amino spacer. One of a set of synthesised biotinylated oligo-alpha-(1->4)-D-galactosamines comprising from two to six monosaccharide units, along with their N-acetylated derivatives (PMID:31913631), aimed at analysing the specificity of the antibody responses to a complex exopolysaccharide galactosaminogalactan found in Aspergillus fumigatus, the most important airborne human fungal pathogen in industrialized countries.


An N-glycosyl compound that is a metabolite produced by the bacterium Mycoplasma genitalium.


name: 3-hydroxy-2-phenylpropanoic acid [(1R,5R)-8-methyl-8-propan-2-yl-8-azoniabicyclo[3.2.1]octan-3-yl] ester


A tetrasaccharide derivative in which N-acetyl-alpha-D-galactosaminyl-(1->4)-N-acetyl-alpha-D-galactosaminyl-(1->4)-N-acetyl-alpha-D-galactosaminyl-(1->4)-N-acetyl-alpha-D-galactosamine is linked glycosidically to biotin via a (21-oxo-3,6,9,12,15,18-hexaoxa-22-azapentacosan-1-yl)amino spacer. One of a set of synthesised biotinylated oligo-alpha-(1->4)-D-galactosamines comprising from two to six monosaccharide units, along with their N-acetylated derivatives (PMID:31913631), aimed at analysing the specificity of the antibody responses to a complex exopolysaccharide galactosaminogalactan found in Aspergillus fumigatus, the most important airborne human fungal pathogen in industrialized countries.


A disaccharide derivative in which N-acetyl-alpha-D-galactosaminyl-(1->4)-N-acetyl-alpha-D-galactosamine is linked glycosidically to biotin via a (21-oxo-3,6,9,12,15,18-hexaoxa-22-azapentacosan-1-yl)amino spacer. One of a set of synthesised biotinylated oligo-alpha-(1->4)-D-galactosamines comprising from two to six monosaccharide units, along with their N-acetylated derivatives (PMID:31913631), aimed at analysing the specificity of the antibody responses to a complex exopolysaccharide galactosaminogalactan found in Aspergillus fumigatus, the most important airborne human fungal pathogen in industrialized countries.


A member of the class of azabicycloalkanes that is 1-azabicyclo[3.2.0]heptan-7-one substituted at positions 3 and 6 by (2-aminoethyl)thio and ethyl groups respectively.


name: 2-(4-bromophenyl)propanoic acid (8-methyl-8-azabicyclo[3.2.1]octan-3-yl) ester


(R)-atropine

An atropine with a 2R-configuration.


name: 2-hydroxy-2-phenylacetic acid [(5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] ester


biotin sulfone

A member of the class of biotins that is biotin sulfoxide with a sulfone group replacing the sulfoxide.


ecgonone methyl ester

The methyl ester of (1R,2R,5S)-8-methyl-3-oxo-8-azabicyclo[3.2.1]octane-2-carboxylic acid (ecgonone).


biotin amide

A monocarboxylic acid amide derived from  biotin.


saxagliptin

A monocarboxylic acid amide obtained by formal condensation of the carboxy group of (2S)-amino(3-hydroxyadamantan-1-yl)acetic acid with the amino group of (1S,3S,5S)-2-azabicyclo[3.1.0]hexane-3-carbonitrile. Used in its monohydrate form for the treatment of Type II diabetes.


MARAVIROC

A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 4,4-difluorocyclohexanecarboxylic acid and the primary amino group of (1S)-3-[(3-exo)-3-(3-isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]oct-8-yl]-1-phenylpropylamine. An antiretroviral drug, it prevents the interaction of HIV-1 gp120 and chemokine receptor 5 (CCR5) necessary for CCR5-tropic HIV-1 to enter cells.


name: (2S)-3-hydroxy-2-phenylpropanoic acid [(5R)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] ester


A member of the class of azabicycloalkanes that is 1,3-diazabicyclo[2.2.0]hex-4-en-2-one substituted at position 6 by a 5,6-diamino-2-oxo-2,3,4,5-tetrahydropyrimidin-4-yl group.


durlobactam

A member of the class of azabicycloalkanes that is (1R,2S,5R)-3-methyl-7-oxo-1,6-diazabicyclo[3.2.1]oct-3-ene-2-carboxamide in which the amino hydrogen at position 6 is replaced by a sulfooxy group.


name: (1R,3S)-3-(4-iodophenyl)-8-methyl-8-azabicyclo[3.2.1]octane-4-carboxylic acid methyl ester


name: 3-hydroxy-2-phenylpropanoic acid [(5S)-8,8-dimethyl-8-azoniabicyclo[3.2.1]octan-3-yl] ester


tedisamil

A member of the class of diazabicyclononanes that is (1s,5s)-3,7-diazaspiro[bicyclo[3.3.1]nonane-9,1'-cyclopentane] in which the hydrogens at positions 3 and 7 are replaced by cyclopropylmethyl groups. It is a potassium channel blocker and an antiarrhythmic agent currently currently in development for the treatment of atrial fibrillation.


A tetrasaccharide derivative in which alpha-D-galactosaminyl-(1->4)-alpha-D-galactosaminyl-(1->4)-alpha-D-galactosaminyl-(1->4)-alpha-D-galactosamine is linked glycosidically to biotin via a (21-oxo-3,6,9,12,15,18-hexaoxa-22-azapentacosan-1-yl)amino spacer. One of a set of synthesised biotinylated oligo-alpha-(1->4)-D-galactosamines comprising from two to six monosaccharide units, along with their N-acetylated derivatives (PMID:31913631), aimed at analysing the specificity of the antibody responses to a complex exopolysaccharide galactosaminogalactan found in Aspergillus fumigatus, the most important airborne human fungal pathogen in industrialized countries.


tropisetron

An indolyl carboxylate ester obtained by formal condensation of the carboxy group of indole-3-carboxylic acid with the hydroxy group of tropine.


name: 3-hydroxy-2-phenylpropanoic acid (8-methyl-8-azabicyclo[3.2.1]octan-3-yl) ester


A hexasaccharide derivative in which alpha-D-galactosaminyl-(1->4)-alpha-D-galactosaminyl-(1->4)-alpha-D-galactosaminyl-(1->4)-alpha-D-galactosaminyl-(1->4)-alpha-D-galactosaminyl-(1->4)-alpha-D-galactosamine is linked glycosidically to biotin via a (21-oxo-3,6,9,12,15,18-hexaoxa-22-azapentacosan-1-yl)amino spacer. One of a set of synthesised biotinylated oligo-alpha-(1->4)-D-galactosamines comprising from two to six monosaccharide units, along with their N-acetylated derivatives (PMID:31913631), aimed at analysing the specificity of the antibody responses to a complex exopolysaccharide galactosaminogalactan found in Aspergillus fumigatus, the most important airborne human fungal pathogen in industrialized countries.


name: 2-hydroxy-2-phenylacetic acid [(5S)-8,8-dimethyl-8-azoniabicyclo[3.2.1]octan-3-yl] ester


ramiprilat

A dipeptide that is the active metabolite of ramipril. An angiotensin-converting enzyme (ACE) inhibitor, used to treat high blood pressure and congestive heart failure.


biotins

Compounds containing a biotin (5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoic acid) skeleton.


ramipril

A dipeptide that is the prodrug for ramiprilat, the active metabolite obtained by hydrolysis of the ethyl ester group. An angiotensin-converting enzyme (ACE) inhibitor, used to treat high blood pressure and congestive heart failure.


biotin sulfoxide

A sulfoxide that is the S-oxide of biotin.


An N-glycosyl compound that is a metabolite produced by the bacterium Mycoplasma genitalium.


hapten GNL

An azabicycloalkane that consists of ecgonine having phenylphosphonyl and alkyl groups attached to the hydroxy and carboxy groups respectively. Used as a transition state analogue of cocaine.


A tropane alkaloid that is (1R,5)-8-methyl-8-azabicyclo[3.2.1]octane substituted by a (3-hydroxy-2-phenylpropanoyl)oxy group at position 3.


deptropine

An azabicycloalkane that is the 10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-yl ether of tropine.


name: 2-hydroxy-2-phenylacetic acid [(1R,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] ester


O-benzoylecgonine 5-carboxypentyl ester

An azabicycloalkane that consists of ecgonine having benzoyl and 5-carboxypentyl groups attached to the hydroxy and carboxy functions respectively.


hyoscyamine

An atropine with a 2S-configuration.


BICOZAMYCIN

A commercially important azabicyclic antibiotic obtained from Streptomyces sapporonensis. It inhibits the Rho protein of E. coli.


An azabicycloalkane that consists of a hexahydropyrimidine ring fused with a cyclopentane ring at positions 2 and 3.


A pentasaccharide derivative in which alpha-D-galactosaminyl-(1->4)-alpha-D-galactosaminyl-(1->4)-alpha-D-galactosaminyl-(1->4)-alpha-D-galactosaminyl-(1->4)-alpha-D-galactosamine is linked glycosidically to biotin via a (21-oxo-3,6,9,12,15,18-hexaoxa-22-azapentacosan-1-yl)amino spacer. One of a set of synthesised biotinylated oligo-alpha-(1->4)-D-galactosamines comprising from two to six monosaccharide units, along with their N-acetylated derivatives (PMID:31913631), aimed at analysing the specificity of the antibody responses to a complex exopolysaccharide galactosaminogalactan found in Aspergillus fumigatus, the most important airborne human fungal pathogen in industrialized countries.


name: O-hydroxy(phenyl)phosphinoyl ecgonine methyl ester

description: The O-hydroxy(phenyl)phosphinoyl derivative of ecgonine methyl ester.


A member of the class of azabicycloalkanes that is 1-azabicyclo[3.2.0]heptan-7-one substituted at position 3 by a (2-aminoethyl)thio group.


ioflupane

An azabicycloalkane that is ecgonine methyl ester in which the N-methyl group is replaced by 3-fluoropropyl and the 3beta-hydroxy group is replaced by 4-((123)I)iodophenyl. Used for the imaging of dopamine transporters in the brain of adult patients with potential Parkinsonian Syndromes.


tropine

A derivative of tropane having a hydroxy group at the 3-position.


avibactam

A member of the class of azabicycloalkanes that is (2S,5R)-7-oxo-1,6-diazabicyclo[3.2.1]octane-2-carboxamide in which the amino hydrogen at position 6 is replaced by a sulfooxy group. Used (in the form of its sodium salt) in combination with ceftazidime pentahydrate for the treatment of complicated urinary tract infections including pyelonephritis.


TROPANSERIN

A tropane alkaloid that consists of tropine in which the hydrogen of the hydroxy function is substituted by a 3,5-dimethylbenzoyl group.


A trisaccharide derivative in which alpha-D-galactosaminyl-(1->4)-alpha-D-galactosaminyl-(1->4)-alpha-D-galactosamine is linked glycosidically to biotin via a (21-oxo-3,6,9,12,15,18-hexaoxa-22-azapentacosan-1-yl)amino spacer. One of a set of synthesised biotinylated oligo-alpha-(1->4)-D-galactosamines comprising from two to six monosaccharide units, along with their N-acetylated derivatives (PMID:31913631), aimed at analysing the specificity of the antibody responses to a complex exopolysaccharide galactosaminogalactan found in Aspergillus fumigatus, the most important airborne human fungal pathogen in industrialized countries.


An azabicycloalkane that is (1R,4R)-2,5-diazabicyclo[2.2.1]heptane which is substituted at position 2 by a 3-(2-hydroxyphenyl)-3-oxoprop-1-en-1-yl group and at position 5 by a pyridin-2-yl group. It is a potent and selective inhibitor of polybromo 1 (Kd = 48 nM), SMARCA2 and SMARCA4 (Kd = 89 nM) bromodomains.


A trisaccharide derivative in which N-acetyl-alpha-D-galactosaminyl-(1->4)-N-acetyl-alpha-D-galactosaminyl-(1->4)-N-acetyl-alpha-D-galactosamine is linked glycosidically to biotin via a (21-oxo-3,6,9,12,15,18-hexaoxa-22-azapentacosan-1-yl)amino spacer. One of a set of synthesised biotinylated oligo-alpha-(1->4)-D-galactosamines comprising from two to six monosaccharide units, along with their N-acetylated derivatives (PMID:31913631), aimed at analysing the specificity of the antibody responses to a complex exopolysaccharide galactosaminogalactan found in Aspergillus fumigatus, the most important airborne human fungal pathogen in industrialized countries.


trovafloxacin

A 1,8-naphthyridine derivative that is 4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid bearing additional 2,4-difluorophenyl, fluoro and  6-amino-3-azabicyclo[3.1.0]hex-3-yl substituents at positions 1, 6 and 7 respectively. A broad-spectrum antibiotic that was withdrawn from the market due to risk of liver failure.


ecgonine

A tropane alkaloid that consists of tropane bearing carboxy and hydroxy substituents at positions 2 and 3 respectively and having (1R,2R,3S,5S)-configuration. It is both a metabolite of and a precursor to cocaine.


scopolamine

A tropane alkaloid that is the (S)-tropic acid ester of 6beta,7beta-epoxy-1alphaH,5alphaH-tropan-3alpha-ol.


intermedine

A carboxylic ester compound formed from condensation between retronecine and (2S,3R)-2,3-dihydroxy-2-isopropylbutanoic acid.


A pentasaccharide derivative in which N-acetyl-alpha-D-galactosaminyl-(1->4)-N-acetyl-alpha-D-galactosaminyl-(1->4)-N-acetyl-alpha-D-galactosaminyl-(1->4)-N-acetyl-alpha-D-galactosaminyl-(1->4)-N-acetyl-alpha-D-galactosamine is linked glycosidically to biotin via a (21-oxo-3,6,9,12,15,18-hexaoxa-22-azapentacosan-1-yl)amino spacer. One of a set of synthesised biotinylated oligo-alpha-(1->4)-D-galactosamines comprising from two to six monosaccharide units, along with their N-acetylated derivatives (PMID:31913631), aimed at analysing the specificity of the antibody responses to a complex exopolysaccharide galactosaminogalactan found in Aspergillus fumigatus, the most important airborne human fungal pathogen in industrialized countries.


A member of the class of azabicycloalkanes that is 1-azabicyclo[3.2.0]heptan-7-one substituted at positions 3 and 6 by (2-aminoethyl)thio and methyl groups respectively.


A beta-D-glucoside compound having a (pentanoyl)-phloroglucinyl moiety at the anomeric position. Isolated from the whole plant of Indigofera heterantha, it exhibits lipoxygenase inhibitory activity.


An omega-hydroxy fatty acid ascaroside that is oscr#18 in which the pro-R hydrogen beta to the carboxy group is replaced by a hydroxy group. It is a metabolite of the nematode Caenorhabditis elegans.


GDP-beta-L-fucose

A GDP-L-fucose in which the anomeric oxygen is on the same side of the fucose ring as the methyl substituent.


name: ammonium magnesium phosphate hexahydrate

description: A hydrate that is the hexahydrate form of ammonium magnesium phosphate. It is a constituent of urinary calculi.


fluorapatite

A phosphate mineral with the formula Ca5(PO4)3F.


chlorapatite

A phosphate mineral with the formula Ca5(PO4)3Cl.


apatite

A phosphate mineral with the general formula Ca5(PO4)3X where X = OH, F or Cl.


emeraldine polymer

A polyaniline polymer, composed of emeraldine macromolecules.


An iridium coordination entity composed of iridium(III) coordinated to an acetoacetonate and two 7-(diethylamino)-3-(1-methyl-1H-benzimidazol-2-yl)-2H-chromen-2-one units.


An iridium coordination entity composed of iridium(III) coordinated to an acetoacetonate and two 3-(1,3-benzothiazol-2-yl)-7-(diethylamino)-2H-chromen-2-one units.


A perchlorometallate anion having six chlorines and rhodium(IV) as the metal component.


mu-chloro-bridged dimer of iridium(III) bis [3-(benzothiazol-2-yl)-7-(diethylamino)coumarin)]


flucloxacilloyl-L-lysine

An L-lysine derivative obtained from nucleophilic cleavage of the beta-lactam ring of flucloxacillin by the epsilon-amino group of the L-lysine molecule.


Cervical Squamotransitional Carcinoma

description: A human papillomavirus-related cervical squamous cell carcinoma characterized by the presence of papillary structures with fibrovascular cores. It is covered with multiple layers of atypical cells that resemble cervical intraepithelial neoplasia 3.


2-aminobut-2-enoic acid zwitterion

An amino acid zwitterion obtained by transfer of a proton from the carboxy to the amino group of 2-aminobut-2-enoic acid; major species at pH 7.3.


A heparin tetradecasaccharide consisting of 4-deoxy-2-O-sulfo-alpha-L-threo-hex-4-enopyranuronosyl, 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranosyl, 2-O-sulfo-alpha-L-idopyranuronosyl, 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranosyl, 2-O-sulfo-alpha-L-idopyranuronosyl, 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranosyl, 2-O-sulfo-alpha-L-idopyranuronosyl, 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranosyl, 2-O-sulfo-alpha-L-idopyranuronosyl, 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranosyl, alpha-L-idopyranuronosyl, 2-acetamido-2-deoxy-6-O-sulfo-alpha-D-glucopyranosyl, beta-D-glucopyranuronosyl, and 2-deoxy-3,6-di-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose units joined in sequence by (1->4) linkages. Sequence: DUA2S-[-GlcNS6S-IdoA2S-]4-GlcNS6S-IdoA-GlcNAc6S-GlcA-GlcNS3S6S.


heparin tetradecasaccharide

Any heparin oligosaccharide consisting of 14 glycosidically linked monosaccharide residues.


A heparin tetradecasaccharide consisting of 4-deoxy-2-O-sulfo-alpha-L-threo-hex-4-enopyranuronosyl, 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranosyl, 2-O-sulfo-alpha-L-idopyranuronosyl, 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranosyl, 2-O-sulfo-alpha-L-idopyranuronosyl, 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranosyl, 2-O-sulfo-alpha-L-idopyranuronosyl, 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranosyl, 2-O-sulfo-alpha-L-idopyranuronosyl, 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranosyl, 2-O-sulfo-alpha-L-idopyranuronosyl, 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranosyl, 2-O-sulfo-alpha-L-idopyranuronosyl, and 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose units joined in sequence by (1->4) linkages. Sequence: DUAp2S-(1-4)-a-D-GlcNpS6S-(1-4)-a-L-IdoAp2S-(1-4)-a-D-GlcNpS6S-(1-4)-a-L-IdoAp2S-(1-4)-a-D-GlcNpS6S-(1-4)-a-L-IdoAp2S-(1-4)-a-D-GlcNpS6S-(1-4)-a-L-IdoAp2S-(1-4)-a-D-GlcNpS6S-(1-4)-a-L-IdoAp2S-(1-4)-a-D-GlcNpS6S-(1-4)-a-L-IdoAp2S-(1-4)-a-D-GlcNpS6S.


An N-acyl-1-O-beta-D-glucosyl-4-hydroxy-15-methylhexadecasphinganine in which the acyl group has 17 carbons and 0 double bonds and is 2-hydroxylated.


ISOXATHION

An organic thiophosphate  that is O,O-diethyl hydrogen phosphorothioate in which the hydrogen of the hydroxy group is replaced by a 5-phenyl-1,2-oxazol-3-yl group.


N(6)-acyl-L-lysine zwitterion

Zwitterionic form of an N(6)-acyl-L-lysine.


Zwitterionic form of N(6)-[(indol-3-yl)acetyl]-L-lysine arising from transfer of a proton from the carboxy to the amino group; major species at pH 7.3.


Transformed migraine

description: Episodes of migraine occurring on 15 or more days per month, for more than three months.


tributylsilyl group

An organosilyl group consisting of three n-butyl groups attached to a silicon atom.


organosilyl group

An organyl derivative of the silyl group, R3Si-.


trimethylsilyl group

An organosilyl group consisting of three methyl groups bonded to a silicon atom with a free valence on silicon for bonding to the rest of a molecule.


name: 1-[2-[[(2-chloroanilino)-oxomethyl]amino]-2-methyl-1-oxopropyl]-4-piperidinecarboxylic acid ethyl ester


name: E. coli strain 0111 B4 lipopolysaccharide

description: A lipopolysaccharide that is produced by E. coli strain 0111 B4.


alvaradoin L

A C-glycosyl compound that is 1,8-dihydroxy-3-methylanthracen-9(10H)-one substituted by a 2-O-senecioyl-alpha-lyxopyranosyl moiety at position 10 via a C-glycosidic linkage (the 10S stereoisomer). It is isolated from the leaves of Alvaradoa haitiensis and exhibits cytotoxicity against human oral epidermoid carcinoma.


L-isoleucine 2-naphthylamide

An L-isoleucine derivative that is the amide obtained by formal condensation of the carboxy group of L-isoleucine with the amino group of 2-naphthylamine.


sodium bromate

An inorganic sodium salt having bromate as the counterion.


description: A reactive proliferation of the conjunctival epithelium associated with the presence of prominent glandular elements.


Spinal arthritis deformans

description: Degenerative arthritis of the spinal column.


name: Amyotrophic Lateral Sclerosis 14, With or Without Frontotemporal Dementia

description: A form of amyotrophic lateral sclerosis caused by heterozygous mutation(s) in the VCP gene, encoding transitional endoplasmic reticulum ATPase.


Spastic Paraplegia 30

description: An autosomal recessive subtype of hereditary spastic paraplegia caused by mutation(s) in the KIF1A gene, encoding kinesin-like protein KIF1A.


Presenile dementia

description: The presence of dementia in an individual younger than age sixty five.


Amyotrophic Lateral Sclerosis 25

description: An autosomal dominant form of amyotrophic lateral sclerosis caused by mutation(s) in the KIF5A gene, encoding kinesin heavy chain isoform 5A.


Spastic Paraplegia 76

description: An autosomal recessive subtype of hereditary spastic paraplegia caused by mutation(s) in the CAPN1 gene, encoding calpain-1 catalytic subunit.


name: Neurodegeneration with Brain Iron Accumulation 2A

description: An autosomal recessive condition caused by mutation(s) in the PLA2G6 gene, encoding 85/88 kDa calcium-independent phospholipase A2. It is characterized by axonal swelling and spheroid bodies in the central nervous system. The onset is typically in the first two years of life.


palmitoleyl alcohol

A member of the class of hexadecen-1-ols that is hexadecanol containing a double bond located at position 9 (the Z-geoisomer).


An optically active 5-oxo-1,2-campholide having (-)-(1R,5R)-configuration.


LUCENSIMYCIN E

An organic heterotetracyclic compound isolated from the bacterial strain Streptomyces lucensis MA7349 and has been shown to exhibit antibacterial activity.


A bridged compound that is 1,2-campholide substituted at position 5 by an oxo group.


An optically active 5-oxo-1,2-campholide having (+)-(1S,5S)-configuration.


A diarylheptanoid that is (6E)-6-hepten-3-ol substituted by a 3,4-dihydroxyphenyl group at position 1 and a phenyl group at position 7 (the 3R- stereoisomer). It has been isolated from the rhizomes of Curcuma kwangsiensis.


PRENISTEINE

A prenylcysteine where the prenyl moiety is attached to the side-chain sulfur atom of L-cysteine.


prenylcysteine

A derivative of the amino acid cysteine formed by the covalent addition of a prenyl residue.


beta-cypermethrin

A diastereoisomeric mixture comprising the enantiomeric pair (1R)-cis-(alphaS)- and (1S)-cis-(alphaR)-cypermethrin in ratio approximately 2:3 with the enantiomeric pair (1S)-trans-(alphaR)- and (1R)-trans-(alphaS)-cypermethrin.


name: Unresectable Pancreatic Neuroendocrine Tumor G3

description: Pancreatic neuroendocrine tumor G3 that is not amenable to surgical resection.


A member of the class of delta-lactams that is 2-piperidinone in which the amide hydrogen is replaced by a 4-bromobutyl group.


An N-glycosyl compound that is a metabolite produced by the bacterium Mycoplasma genitalium.


plakortolide S

An organic heterobicyclic compound that is a cyclic peroxy compound isolated from the Australian marine sponge Plakinastrella clathrata.


N-ethyl-L-asparagine

An optically active form of N-ethylasparagine having L-configuration.


N-ethylasparagine

A dicarboxylic acid monoamide that is asparagine in which one of the hydrogens attached to the nitrogen of the alpha-amino group is replaced by an ethyl group.


name: 4-[2-[[1-[(2-methylphenyl)methyl]-3-indolyl]sulfonyl]-1-oxoethyl]-1-piperazinecarboxylic acid ethyl ester


hydrocortisone phosphate

A steroid phosphate that is the 21-O-phospho derivative of cortisol.


prednisolone sodium phosphate

A synthetic glucocorticoid resulting from the formal condensation of the 21-hydroxy group of prednisolone with one of the hydroxy groups of phosphoric acid. It is a prodrug for prednisolone that is activated in vivo by phosphatases.


estramustine phosphate

A steroid phosphate which is the 17-O-phospho derivative of estramustine.


betamethasone phosphate

A steroid phosphate that is the 21-O-phospho derivative of betamethasone.


dexamethasone phosphate

A steroid phosphate that is the 21-O-phospho derivative of dexamethasone.


A hydroxyoctadecatrienoic acid that consists of 6Z,9Z,11E-octadecatrienoic acid having the hydroxy group located at position 13.


name: Adult Acute Myeloid Leukemia with inv(16)(p13.1q22); CBFB-MYH11

description: An acute myeloid leukemia with inv(16)(p13.1q22); CBFB-MYH11 occurring in adults.


An acyl tetraketide pyran-2-one that is 4-hydroxy-2H-pyran-2-one in which the hydrogen at position 6 is replaced by a 13-methyl-2-oxotetradecyl group.


2-amino-4-oxopentanoic acid zwitterion

Zwitterionic form of 2-amino-4-oxopentanoic acid having an anionic carboxy group and a protonated amino group.


A 2-amino-4-oxopentanoic acid zwitterion obtained by transfer of a proton from the carboxy to the amino group of (R)-2-amino-4-oxopentanoic acid; major microspecies at pH 7.3.


name: 2-[4-(3-chlorophenyl)-1-piperazinyl]-3-pyridinecarboxylic acid propan-2-yl ester


A 2-methylbutyronitrile that has S configuration.


A glycosylglycerol that is  1-O-(D-glucosyl)glycerol in which the secondary hydroxy group of the glycerol moiety has been converted into the corresponding L-fucopyranoside.


isoferulic acid

A ferulic acid consisting of trans-cinnamic acid bearing methoxy and hydroxy substituents at positions 4 and 3 respectively on the phenyl ring.


FERULATE

A ferulic acid consisting of trans-cinnamic acid bearing methoxy and hydroxy substituents at positions 3 and 4 respectively on the phenyl ring.


cis-ferulic acid

A ferulic acid consisting of cis-cinnamic acid bearing methoxy and hydroxy substituents at positions 3 and 4 respectively on the phenyl ring.


An amino disaccharide consisting of 2-acetamido-2-deoxy-beta-D-glucopyranose and D-galactopyranose residues joined by a (1->3) glycosidic bond.


Ala-Eth

A dipeptide formed from L-alanyl and L-ethionine residues.


A 2-keto-xylose having D-threo configuration; a degradation product of D-ascorbic acid.


Moniliform hamartoma

description: A type of pilosebaceous hamartoma characterized by the development of a linear, flesh colored, fine papular eruption on the head, neck and upper chest after puberty.


Apocrine Sweat Gland Hamartoma

description: A hamartoma characterized by localized apocrine sweat gland malformation.


name: Recurrent Endometrial Undifferentiated Carcinoma

description: The reemergence of endometrial undifferentiated carcinoma after a period of remission.


name: Metastatic Endometrial Undifferentiated Carcinoma

description: Endometrial undifferentiated carcinoma that has spread from its original site of growth to another anatomic site.


name: Refractory Endometrial Undifferentiated Carcinoma

description: Endometrial undifferentiated carcinoma that is resistant to treatment.


name: Esophageal Gastrointestinal Stromal Tumor

description: A gastrointestinal stromal tumor that arises from the esophagus.  The majority are spindle cell tumors that exhibit high mitotic activity and affect the distal esophagus.


name: 2-(2-methyl-1-benzimidazolyl)acetic acid [2-(2-methyl-1H-indol-3-yl)-2-oxoethyl] ester


An alpha-hydroxyglycine that has S configuration.


alpha-hydroxyglycine

A hydroxy-amino acid that is glycine substituted by a hydroxy group at the alpha-position.


An N-acyl-(2S)-hydroxyglycine resulting from the formal condensation of dodecanoic acid (lauric acid) with the amino group of (2S)-hydroxyglycine.


ISOBUTYLBENZENE

An alkylbenzene that is benzene carrying an isobutyl substituent.


name: 6,6-dimethyl-4-oxo-3-(phenylmethylthio)-5,7-dihydro-2-benzothiophene-1-carboxylic acid ethyl ester


ACETONE

A methyl ketone that consists of propane bearing an oxo group at C2.


uridine residue

The nucleoside residue formed from uridine with linkages at the 3' and 5' positions.


Tyr-Thr

A dipeptide obtained by formal condensation of the carboxy group of L-tyrosine with the amino group of L-threonine.


A benzamide that is GRL-0617 in which one of the hydrogen's of the primary amino group is replaced by an acetyl group. It an inhibitor of SARS-CoV and SARS-CoV-2 papain-like protease (PLpro) with an IC50 of 2.6 muM and 5.0 muM, respectively. It also inhibits SARS-CoV and SARS-CoV-2 infection of Vero E6 cells in vitro (EC50 values are 13.1 and 21 muM, respectively).


A pyridone that is 6-oxo-1,6-dihydropyridine-2-carboxylic acid substituted by a 2-carboxyethyl group at position 5.


glycylglycine

A dipeptide formed from glycine residues.


name: Stage IVB Oral Cavity Squamous Cell Carcinoma AJCC v6 and v7

description: Stage IVB includes: (Any T, N3, M0); (T4b, Any N, M0). T4b: Oral cavity cancer with very advanced local disease.  Tumor invades masticator space, pterygoid plates, or skull base and/or encases internal carotid artery. N3: Metastasis in a lymph node more than 6 cm in greatest dimension. M0: No distant metastasis. (AJCC 7th ed.)


name: Stage IVB Lip and Oral Cavity Cancer AJCC v6 and v7

description: Stage IVB includes: (Any T, N3, M0); (T4b, Any N, M0). T4b: Lip and oral cavity cancer with very advanced local disease.  Tumor invades masticator space, pterygoid plates, or skull base and/or encases internal carotid artery. N3: Metastasis in a lymph node more than 6 cm in greatest dimension. M0: No distant metastasis. (AJCC 7th ed.)


name: Stage IVB Oral Cavity Adenoid Cystic Carcinoma AJCC v6 and v7


name: Stage IVB Oral Cavity Mucoepidermoid Carcinoma AJCC v6 and v7


name: Stage IVB Lip and Oral Cavity Squamous Cell Carcinoma AJCC v6 and v7

description: Stage IVB includes: (Any T, N3, M0); (T4b, Any N, M0). T4b: Lip and oral cavity cancer with very advanced local disease. Tumor invades masticator space, pterygoid plates, or skull base and/or encases internal carotid artery. N3: Metastasis in a lymph node more than 6 cm in greatest dimension. M0: No distant metastasis. (AJCC 7th ed.)


name: Stage IVB Oral Cavity Cancer AJCC v6 and v7


Stage IVB Lip Cancer AJCC v6 and v7

description: Stage IVB includes: (Any T, N3, M0); (T4b, Any N, M0). T4b: Lip cancer with very advanced local disease.  Tumor invades masticator space, pterygoid plates, or skull base and/or encases internal carotid artery. N3: Metastasis in a lymph node more than 6 cm in greatest dimension. M0: No distant metastasis. (AJCC 7th ed.)


omega-hydroxyoctacosanoic acid

An omega-hydroxy fatty acid that is octacosanoic acid substituted by a hydroxy group at position 28.


ORTHO-PHTHALALDEHYDE

A dialdehyde in which two formyl groups are attached to adjacent carbon centres on a benzene ring.


methyl beta-D-glucopyranoside

A beta-D-glucopyranoside having a methyl substituent at the anomeric position.


α-MDG

An alpha-D-glucopyranoside having a methyl substituent at the anomeric position.


fusahexin

A cyclic hexapeptide with the amino acid sequence cyclo-(D-Ala-L-Leu-D-allo-Thr-L-Pro-D-Leu-L-Leu). Fusahexin is a secondary metabolite produced by the plant pathogenic fungus Fusarium graminearum.


dUMP residue

The canonical deoxyribonucleotide residue formed from dUMP (2'-deoxy-5'-uridylic acid).


A hydroxycoumarin that is 4,7-dihydroxycoumarin bearing an additional amino substituent at positions 3.


A purine 2'-deoxyribonucleoside 5'-monophosphate having 6-O-benzylguanine as the nucleobase.


flutrimazole

An imidazole antifungal agent that is imidazole in which the hydrogen attached to the nitrogen is replaced by a 2,4'-difluorotrityl group. A topical antifungal agent which displays potent broad-spectrum in vitro activity against dermatophytes, filamentous fungi and yeasts.


name: Pathologic Stage IB Cutaneous Melanoma AJCC v8

description: Stage IB includes: T2a, N0, M0. T2a: Tumor measuring more than 1.0 and equal to or less than 2.0 mm in thickness. Ulceration status: Without ulceration. N0: No regional lymph node metastasis detected. Presence of in-transit, satellite, and/or microsatellite metastases: No. M0: No evidence of distant metastasis. LDH level is not applicable. (AJCC 8th ed.)


A chloroethanol carrying a chloro substituent at position 2.


LURASIDONE HYDROCHLORIDE

A hydrochloride obtained by reaction of lurasidone with one equivalent of hydrochloric acid. An atypical antipsychotic agent used for the treatment of schizophrenia.


Vein of Galen Malformations

description: An arteriovenous malformation in the vein of Galen that is located at the base of the brain. The malformation may result in developmental delays, hydrocephalus, seizures, and congestive heart failure.


name: Dextro-Transposition of the Great Vessels with Ventricular Septal Defect

description: A congenital heart defect in which there is an abnormal arrangement of any of the primary blood vessels of the heart in conjunction with a pathologic opening between the cardiac ventricles.


phenosafranine

An organic chloride salt having 3,7-diamino-5-phenylphenazin-5-ium as the counterion. It is commonly used for staining Gram negative bacteria red in smears to contrast with the blue Gram positive organisms.


JASPAMIDE L

A cyclodepsipeptide isolated from Jaspis splendens. A derivative of jaspamide, it has been shown to exhibit cytotoxic and microfilament disruption activity.


arthothelin

A member of the class of xanthones that is 9H-xanthen-9-one substituted by hydroxy groups at positions 1, 3 and 6, chloro groups at positions 2, 4 and 5 and a methyl group at position 8. It has been isolated from the lichen, Lecanora iseana.


name: 3-(3-methoxyphenyl)-2-propenoic acid [2-oxo-2-[4-(1-pyrrolidinylsulfonyl)anilino]ethyl] ester


heptylmalonic acid

A dicarboxylic acid that is malonic acid substituted with a heptyl group at position C-2.


His-Tyr

A dipeptide formed from L-histidine and L-tyrosine residues.


Ile-Lys

A dipeptide obtained by formal condensation of the carboxy group of L-isoleucine with the amino group of L-lysine.


cyclo(L-His-L-Pro)

A homodetic cyclic peptide resulting from the formal condensation of both the amino and acid groups of L-histidine with the acid and amino groups of L-proline. It is a metabolite of thyrotropin-releasing hormone (TRH).


gamma-Glu-His

A glutamyl-L-amino acid obtained by formal condensation of the gamma-carboxy group of glutamic acid with the amino group of histidine.


Gly-Leu

A dipeptide composed of glycine and L-leucine joined by a peptide linkage.


Arg-Phe

A dipeptide formed from L-arginine and L-phenylalanine residues. It exhibits vasorelaxant activity.


Glu-Glu

A dipeptide composed of two L-glutamic acid units joined by a peptide linkage.


Asn-Ile

A dipeptide obtained by formal condensation of the carboxy group of L-asparagine with the amino group of L-isoleucine.


Ile-Pro

A dipeptide formed from L-isoleucine and L-proline residues.


Glu-Cys

A dipeptide composed of L-glutamic acid and L-cysteine joined by a peptide linkage.


Phe-Asn

A dipeptide composed of L-phenylalanine and L-asparagine joined by a peptide linkage.


Trp-Val

A dipeptide formed from L-tryptophan and L-valine residues.


gamma-Glu-Glu

A dipeptide obtained by formal condensation of the gamma-carboxy group of glutamic acid with the amino group of another glutamic acid.


A dipeptide that consists of beta-alanyl-L-glutamine amide bearing a 2-carboxy-4,6-dinitrophenyl (DNCP) substituent at the amino terminus while the amides at the carboxy terminus and side-chain are substituted by beta-D-glucopyranos-2-yl groups.


Thr-Ile

A dipeptide obtained by formal condensation of the carboxy group of L-threonine with the amino group of L-isoleucine.


Ile-Gln

A dipeptide formed from L-isoleucine and L-glutamine residues.


gammaGluCys(IAN)

An S-conjugate dipeptide consisting of L-gamma-glutamyl-L-cysteine in which the the cysteine side chain is substituted by a cyano(indol-3-yl)methyl group.


Pro-Leu

A dipeptide formed from L-proline and L-leucine residues.


Met-Met

A dipeptide formed from two L-methionine residues.


Leu-Gly

A dipeptide formed from L-leucine and glycine residues.


Gly-His

A dipeptide composed of glycine and L-histidine joined by a peptide linkage.


Ile-Ala

A dipeptide formed from L-isoleucine and L-alanine residues.


Gly-Ile

A dipeptide formed from glycine and L-isoleucine residues.


The dipeptide obtained by coupling N-benzyloxycarbonyl-L-tyrosine with the hydroxamic acid derivative of L-leucine. It is an inhibitor of the metallo-protease enzyme, pseudolysin (EC 3.4.24.36).


GLUTAURINE

A dipeptide resulting from the formal condensation of the amino group of taurine with the gamma-carboxy group of L-glutamic acid. It was initially found in the parathyroid in 1980 and later in the brain of mammals.


cyclo(tyrosyl-tyrosyl)

A member of the class of 2,5-diketopiperazines that is piperazine-2,5-dione in which one hydrogen at position 3 and one hydrogen at position 6 are replaced by p-hydroxybenzyl groups.


Gln-Leu

A dipeptide obtained by formal condensation of the carboxy group of L-glutamine with the amino group of L-leucine.


Tyr-Cys

A dipeptide obtained by formal condensation of the carboxy group of L-tyrosine with the amino group of L-cysteine.


Met-FMDP

A  dipeptide  composed of 3-{[(2E)-4-methoxy-4-oxobut-2-enoyl]amino}alanine and L-methionine joined by peptide linkages.


Pro-Asp

A dipeptide formed from L-proline and L-aspartic acid residues.


tabtoxin

A monobactam phytotoxic dipeptide produced by Pseudomonas syringae, that causes wildfire disease in tobacco.


Arg-Arg

A dipeptide formed from two L-arginine residues.


Met-Asp

A dipeptide formed from L-methionine and L-aspartic acid residues.


deoxybrevianamide E

A cyclic dipeptide that is brevianamide F (cyclo-L-Trp-L-Pro) substituted at position 2 on the indole ring by a 1,1-dimethylallyl group.


Lys-Gly

A dipeptide formed from L-lysine and glycine residues.


An S-conjugate in which the mercapto hydrogen of L-cysteinylglycine has been replaced by an N-hydroxy-2-(indol-3-yl)ethanimidoyl group.


Phe-Thr

A dipeptide composed of L-phenylalanine and L-threonine joined by a peptide linkage.


Met-beta-Ala

A dipeptide formed from L-methionine and beta-alanine residues.


A dipeptide formed from L-valine and L-phenylalanine residues.


D-Leu-Gly

A dipeptide formed from D-leucine and glycine residues.


Asp-Trp

A dipeptide formed from L-alpha-aspartyl and L-tryptophan residues.


Lys-Leu

A dipeptide formed from L-lysine and L-leucine residues.


Gly-Ala

A dipeptide formed from glycine and L-alanine residues.


dapdiamide E

A member of the family of dapdiamides consisting of 3-aminoalanylvaline, in which the N-terminus is acylated by a 3-carbamoyloxirane-2-carbonyl group. NB Although the relative configuration of the epoxide moiety has been assigned as trans, it has not yet been established whether the absolute configuration is R,R (as drawn) or S,S.


Ser-Ala

A dipeptide formed from L-serine and L-alanine residues.


bacilysin

A non-ribosomally synthesised dipeptide that consists of L-alanyl and anticapsin units linked by a peptide bond.


TRYPROSTATIN B

A cyclic dipeptide that is brevianamide F (cyclo-L-Trp-L-Pro) substituted at position 2 on the indole ring by a prenyl group.


Ala-Ser

A dipeptide composed of L-alanine and L-serine joined by a peptide linkage.


Asp-Arg

A dipeptide composed of L-aspartic acid and L-arginine joined by a peptide linkage.


gamma-Glu-Trp

A glutamyl-L-amino acid obtained by formal condensation of the gamma-carboxy group of glutamic acid with the amino group of tryptophan.


B 581

A dipeptide obtained from the tetrapeptide Cys-Val-Phe-Met by reduction of the amide carbonyl groups of the Cys and Val residues.


Thr-His

A dipeptide composed of L-threonine and L-histidine joined by a peptide linkage.


Gly-Trp

A dipeptide formed from glycine and L-tryptophan residues.


Tyr-Lys

A dipeptide formed from L-tyrosine and L-lysine residues.


Phe-Glu

A dipeptide formed from L-phenylalanine and L-glutamic acid residues.


Gln-Trp

A dipeptide obtained by formal condensation of the carboxy group of L-glutamine with the amino group of  L-tryptophan.


Pro-Arg

A dipeptide formed from L-proline and L-arginine residues.


Asn-Glu

A dipeptide formed from L-asparagine and L-glutamic acid residues.


Arg-Gln

A dipeptide formed from L-arginyl and L-glutamine residues.


Asn-Ser

A dipeptide composed of L-asparagine and L-serine joined by a peptide linkage.


A dipeptide consisting of N-butyl-L-cysteinamide having an (R)-2-amino-2-(4-hydroxyphenyl)acetyl residue attached to its alpha-amino nitrogen.


Dnp-Trp-Gln

A dipeptide consisting of L-tryptophan substituted on the alpha-nitrogen by a 2,4-dinitrophenyl group and connected to L-glutamine via a peptide bond.


N-acetyl-L-seryl-L-aspartic acid

A dipeptide formed from N-acetyl-L-seryl and L-aspartic acid residues.


Major microspecies at pH 7.3.


chrysobactin

A catechol-type siderophore with a structure of D-lysyl-L-serine substituted on N(2) of the lysyl residue by a 2,3-dihydroxybenzoyl group. It is produced by the Gram-negative bacillus Dickeya dadantii (previously known as Erwinia chrysanthem). Only the catecholate hydroxyl groups participate in metal coordination, so chrysobactin cannot provide full 1:1 coordination of Fe(III); at neutral pH and concentrations of about 0.1 mM, ferric chrysobactin exists as a mixture of bis and tris complexes.


VANCHROBACTIN

A catechol-type natural product that is composed of 2,3-dihydroxybenzoic acid, D-arginine and L-serine joined in sequence by peptide linkages. It is a siderophore synthesized by the bacterial fish pathogen Vibrio anguillarum.


Cys-Ser

A dipeptide composed of L-cysteine and L-serine joined by a peptide linkage.


Gln-Asn

A dipeptide obtained by formal condensation of the carboxy group of L-glutamine with the amino group of  L-asparagine.


Asn-Val

A dipeptide formed from L-asparagine and L-valine residues.


Thr-Glu

A dipeptide formed from L-threonine and L-glutamic acid residues.


beta-Asp-Leu

A dipeptide that is the N-(L-beta-aspartyl) derivative of L-leucine.


Tyr-FMDP

A dipeptide composed of 3-{[(2E)-4-methoxy-4-oxobut-2-enoyl]amino}alanine and L-tyrosine joined by peptide linkages.


L-lysyl-D-alanine

A dipeptide formed from L-lysyl and D-alanyl residues.


A dipeptide composed of L-leucine and L-methioninamide units joined by a peptide linkage. It is a noncompetitive inhibitor of Gap1 transport.


Leu-Cys

A dipeptide composed of L-leucine and L-cysteine joined by a peptide linkage.


Tyr-Gln

A dipeptide formed from L-tyrosine and L-glutamine residues.


Pro-Lys

A dipeptide formed from L-proline and L-lysine residues.


cyclo(L-phenylalanyl-L-phenylalanyl)

A member of the class of 2,5-diketopiperazines that is piperazine-2,5-dione in which one hydrogen at position 3 and one hydrogen at position 6 are replaced by benzyl groups (the 3S,6S-diastereomer).


Val-Tyr

A dipeptide formed from L-valine and L-tyrosine residues.


A dipeptide consisting of N-butyl-L-cysteinamide having an (R)-2-amino-2-phenylacetyl residue attached to its alpha-amino nitrogen.


L-alanyl-L-alanine

A dipeptide consisting of two L-alanine units joined by a peptide linkage.


PLINABULIN

A member of the class of 2,5-diketopiperazines that is piperazine-2,5-dione substituted by benzylidene and (5-tert-butyl-1H-imidazol-4-yl)methylidene groups at positions 3 and 6, respectively. It is a vascular disrupting agent and a microtubule destabalising agent which was in clinical trials (now discontinued) for the treatment of non-small cell lung cancer.


Trp-Leu

A dipeptide formed from L-tryptophan and L-leucine residues.


A dipeptide obtained by formal condensation of the carboxy group of 4-chloro-L-phenylalanine with the amino group of glycine.


L-Lys-D-Asp

A dipeptide obtained by formal condensation of the carboxy group of L-lysine with the amino group of D-aspartic acid. It is a constituent of bacterial peptidoglycan type A4alpha.


His-His

A dipeptide formed from two L-histidine residues.


beta-Asp-Glu

A dipeptide consisting of an L-aspartyl residue attached to L-glutamic acid via the beta-carboxy group.


N-formyl-L-methionyl-L-methionine

A dipeptide that is L-methionyl-L-methionine (Met-Met) in which the nitrogen of the N-terminal amino group has been converted into the corresponding formamide.


Gly-Phe

A dipeptide formed from glycine and L-phenylalanine residues.


Thr-Gly

A dipeptide formed from L-threonine and glycine residues.


Trp-Ser

A dipeptide formed from L-tryptophan and L-serine residues.


glycylsarcosine

A dipeptide obtained by formal condensation of the carboxy group of glycine with the amino group of sarcosine.


Asn-Asp

A dipeptide composed of L-asparagine and L-aspartic acid joined by a peptide linkage.


Ala-Thr

A dipeptide formed from L-alanyl and L-threonine residues.


A dipeptide resulting from the formal coupling of the carboxy group of N(2)-(diphenylacetyl)-D-arginine with the alpha-amino group of D-2-phenylglycinamide.


Ile-Met

A dipeptide formed from L-isoleucine and L-methionine residues.


Ala-Asn

A dipeptide composed of L-alanine and L-asparagine units joined by a peptide linkage.


Gly-Asp

A dipeptide formed from glycyl and L-aspartic acid residues.


Lys-Phe

A dipeptide formed from L-lysine and L-phenylalanine residues.


Ser-Asp

A dipeptide formed from L-serine and L-aspartic acid residues.


Ser-Asn

A dipeptide formed from L-serine and L-asparagine residues.


A dipeptide resulting from the formal condensation of the carboxy group of L-alpha-aminobutyric acid [(2S)-2-aminobutanoic acid] with the amino group of glycine.


Glu-Thr

A dipeptide composed of L-glutamic acid and L-threonine joined by a peptide linkage.


Dnp-Asn-Gln

A dipeptide consisting of L-asparagine substituted on the alpha-nitrogen by a 2,4-dinitrophenyl group and connected to L-glutamine via a peptide bond.


Gly-Arg

A dipeptide formed from glycine and L-arginine residues.


Trp-Gly

A dipeptide formed from L-tryptophan and glycine residues.


Leu-Ser

A dipeptide formed from L-leucine and L-serine residues.


Glu-Val

A glutamyl-L-amino acid that is the N-(L-alpha-glutamyl) derivative of L-leucine.


Met-Ala

A dipeptide formed from L-methionine and L-alanine residues.


Trp-Ala

A dipeptide formed from L-tryptophan and L-alanine residues.


A dipeptide in which the carboxy group of L-homocysteine forms an amide bond with the alpha-nitrogen of N(epsilon)-acetylated L-lysine.


Trp-Asp

A dipeptide formed from L-tryptophan and L-aspartic acid residues.


Ala-Cys

A dipeptide obtained by formal condensation of the carboxy group of L-alanine with the amino group of L-cysteine.


Ser-Glu

A dipeptide formed from L-serine and L-glutamic acid residues.


Met-Ser

A dipeptide composed of L-methionine and L-serine joined by a peptide linkage.


Met-Lys

A dipeptide formed from L-methionine and L-lysine residues.


His-Leu

A dipeptide formed from L-histidine and L-leucine residues.


Ser-Trp

A dipeptide obtained by formal condensation of the carboxy group of L-serine with the amino group of L-tryptophan.


A dipeptide formed from L-arginine and L-phenylalaninamide residues in which a hydrogen attached to the nitrogen of the alpha-amino group of the arginine residue has been replaced by a 1-adamantanecarbonyl group. It has been reported to be a potent and selective antagonist of neuropeptide FF (NPFF) receptors, but more recently found to be an agonist at both NPFF1R and the kisspeptin receptor (KISS1R).


L-seryl-L-tyrosine 2-naphthylamide

An N-(2-naphthyl)carboxamide obtained by formal condensation of the carboxy group of L-seryl-L-tyrosine with the amino group of 2-naphthylamine.


Leu-Tyr

A dipeptide formed from L-leucine and L-tyrosine residues.


Ile-Trp

A dipeptide formed from L-isoleucine and L-tryptophan residues.


A dipeptide that is glutathione in which the amino group on the glutamyl residue has been replaced by an oxo group.


A dipeptide consisting of L-tyrosine substituted on nitrogen and oxygen by 2,4-dinitrophenyl groups and connected to L-glutamine via a peptide bond.


Trp-Arg

A dipeptide formed from L-tryptophan and L-arginine residues.


Leu-Trp

A dipeptide formed from L-leucine and L-tryptophan residues.


D-Leu-D-Leu

A dipeptide formed from two D-leucine residues.


Ser-Tyr

A dipeptide formed from L-serine and L-tyrosine residues.


dapdiamide C

A member of the family of dapdiamides consisting of alanylleucine, in which one of the methyl hydrogens of alanine is replaced by a fumaramoyl group.


beta-alanyl-L-lysine

A dipeptide consisting of beta-alanine and L-lysine units joined by a peptide linkage.


Met-Phe

A dipeptide formed from L-methionine and L-phenylalanine residues.


Met-Val

A dipeptide formed from L-methionine and L-valine residues.


Tyr-Leu

A dipeptide formed from L-tyrosine and L-leucine residues.


His-Phe

A dipeptide obtained by formal condensation of the carboxy group of L-histidine with the amino group of L-phenylalanine.


gamma-glutamylthreonine

A dipeptide composed of glutamic acid and  threonine joined by a peptide linkage.


gamma-Glu-Abu

A dipeptide obtained by formal condensation of the gamma-carboxy group of glutamic acid with the amino group of 2-aminobutyric acid.


cyclo(DeltaAla-L-Val)

A 2,5-diketopiperazine where the substituents are methylidene and (S)-isopropyl at positions  3 and 6 respectively.


Cys-Pro

A dipeptide composed of L-cysteine and L-proline joined by a peptide linkage.


Gly-Ser

A dipeptide composed of glycine and L-serine joined by a peptide linkage.


Pro-Met

A dipeptide obtained by formal condensation of the carboxy group of L-proline with the amino group of L-methionine.


Glu-Arg

A dipeptide composed of L-glutamic acid and L-arginine joined by a peptide linkage.


Asp-Met

A dipeptide obtained by formal condensation of the carboxy group of L-aspartic acid  with the amino group of L-methionine.


beta-Ala-Gly

A dipeptide formed from beta-alanine and glycine residues.


Ile-Asn

A dipeptide formed from L-isoleucine and L-asparagine residues.


Trp-Phe

A dipeptide formed from L-tryptophan and L-phenylalanine residues.


Arg-Lys

A dipeptide formed from L-arginyl and L-leucine residues.


His-Glu

A dipeptide formed from L-histidine and L-glutamic acid residues.


D-Leu-Tyr

A dipeptide formed from D-leucine and L-tyrosine residues.


bis-gamma-glutamylcystine

The dimer obtained by formal oxidative coupling of gamma-glutamylcystine.


Asn-His

A dipeptide composed of L-asparagine and L-histidine joined by a peptide linkage.


Leu-Pro

A dipeptide formed from L-leucine and L-proline residues.


Met-Trp

A dipeptide formed from L-methionine and L-tryptophan residues.


Ala-Lys

A dipeptide obtained by formal condensation of the carboxy group of L-alanine with the alpha-amino group of L-lysine.


Arg-Ser

A dipeptide formed from L-arginine and L-serine residues.


Thr-Pro

A dipeptide formed from L-threonine and L-proline residues.


Ala-Val

A dipeptide formed from L-alanyl and L-valine residues.


gamma-Glu-Phe

A dipeptide obtained by formal condensation of the side-chain carboxy group of L-glutamic acid with the amino group of L-phenylalanine.


glycyl-L-tryptophan 2-naphthylamide

An N-(2-naphthyl)carboxamide obtained by formal condensation of the carboxy group of glycyl-L-tryptophan with the amino group of 2-naphthylamine.


Tyr-Phe

A dipeptide formed from L-tyrosine and L-phenylalanine residues.


Asp-Asp

A dipeptide formed from two L-aspartic acid units.


D-alanyl-D-serine

A dipeptide comprising D-serine with a D-alanyl residue attached to the alpha-nitrogen.


Glu-Tyr

A dipeptide composed of L-glutamic acid and L-tyrosine joined by a peptide linkage.


Lys-Thr

A dipeptide formed from L-lysine and L-threonine residues.


Major species at pH 7.3.


Ala-Asp

A dipeptide formed from L-alanyl and L-aspartic acid residues.


Pro-Gln

A dipeptide formed from L-proline and L-glutamine residues.


CORDYSININ A

A pyrrolopyrazine that is hexahydropyrrolo[1,2-a]pyrazine-1,4-dione substituted by a hydroxy group at position 6 and a 2-methylpropyl group at position 3. It has been isolated from the mycelia of Cordyceps sinensis.


Pro-Phe

A dipeptide formed from L-proline and L-phenylalanine residues.


Glu-Ala

A dipeptide formed from L-alpha-glutamyl and L-alanine residues.


3,5-Diiodotyrosyl-3,5-diiodotyrosine in which each tyrosine residue has L-configuration.


neoechinulin B (anion)

Major microspecies at pH 7.3.


Phe-Trp

A dipeptide formed from L-phenylalanine and L-tryptophan residues.


Asp-Phe

A dipeptide formed from L-alpha-aspartyl and L-phenylalanine residues. It is obtained after the hydrolysis of aspartame in intestinal lumen.


Leu-Asn

A dipeptide composed of L-leucine and L-asparagine joined by a peptide linkage.


Asn-Gln

A dipeptide composed of L-asparagine and L-glutamine joined by a peptide linkage.


Ser-Leu

A dipeptide formed from L-serine and L-leucine residues.


Val-Ser

A dipeptide formed from L-valine and L-serine residues.


Val-Arg

A dipeptide formed from L-valine and L-asparagine residues.


Arg-Tyr

A dipeptide formed from L-arginine and L-tyrosine residues.


Leu-FMDP

A  dipeptide  composed of 3-{[(2E)-4-methoxy-4-oxobut-2-enoyl]amino}alanine and L-leucine joined by peptide linkages.


Ile-His

A dipeptide composed of L-isoleucine and L-histidine joined by a peptide linkage.


Leu-Met

A dipeptide formed from L-leucine and L-methionine residues.


isotabtoxin

A dipeptide obtained by formal condensation of the carboxy group of (2S,5S)-5-(aminomethyl)-5-hydroxy-6-oxopiperidine-2-carboxylic acid (tabtoxinine-delta-lactam) with the amino group of L-threonine.


Gly-D-Ser

A dipeptide formed from glycine and D-serine residues.


rhodotorulic acid

A member of the class of 2,5-diketopiperazines obtained by cyclodimerisation of N(5)-acetyl-N(5)-hydroxy-L-ornithine.


glycyl-L-proline 2-naphthylamide

An N-(2-naphthyl)carboxamide obtained by formal condensation of the carboxy group of glycyl-L-proline with the amino group of 2-naphthylamine.


His-Met

A dipeptide formed from L-histidine and L-methionine residues.


Asp-Thr

A dipeptide obtained by formal condensation of the carboxy group of L-aspartic acid with the amino group of L-threonine.


D-gamma-Glu-Gly

A dipeptide formed from D-gamma-glutamyl and glycine residues.


Asp-Val

A dipeptide formed from L-alpha-aspartyl and L-valine residues.


His-Asp

A dipeptide formed from L-histidine and L-aspartic acid residues.


Glu-Leu

A dipeptide composed of L-glutamic acid and L-leucine joined by a peptide linkage.


Gln-Phe

A dipeptide obtained by formal condensation of the carboxy group of L-glutamine with the amino group of L-phenylalanine.


Dnp-Sar-Gln

A dipeptide consisting of sarcosine (1-methylglycine) substituted on nitrogen by a 2,4-dinitrophenyl group and connected to L-glutamine via a peptide bond.


Phe-Leu

A dipeptide obtained by formal condensation of the carboxy group of L-phenylalanine with the amino group of L-leucine.


Asn-Met

A dipeptide obtained by formal condensation of the carboxy group of L-asparagine with the amino group of L-methionine.


Lys-Asp

A dipeptide formed from L-lysine and L-aspartic acid residues.


Glu-Pro

A dipeptide composed of L-glutamic acid and L-proline joined by a peptide linkage.


Met-Pro

A dipeptide formed from L-methionine and L-proline residues.


Phe-Ser

A dipeptide that is the N-(L-phenylalanyl) derivative of L-serine.


Ser-Thr

A dipeptide obtained by formal condensation of the carboxy group of L-serine with the amino group of L-threonine.


Pro-Ile

A dipeptide formed from L-proline and L-isoleucine residues.


Lys-Pro

A dipeptide formed from L-lysine and L-proline residues.


Lys-Gln

A dipeptide composed of L-lysine and L-glutamine joined by a peptide linkage.


Thr-Asn

A dipeptide obtained by formal condensation of the carboxy group of L-threonine with the amino group of L-asparagine.


spiraprilat

An azaspiro compound that is spirapril in which the ethyl ester group has been hydrolysed to the corresponding carboxylic acid group. It is the active metabolite of the angiotensin-converting enzyme (ACE) inhibitor spirapril.


Met-Glu

A dipeptide formed from L-methionine and L-glutamic acid residues.


dapdiamide B

A member of the family of dapdiamides consisting of alanylisoleucine, in which one of the methyl hydrogens of alanine is replaced by a fumaramoyl group.


Ile-Tyr

A dipeptide formed from L-isoleucine and L-tyrosine residues.


dapdiamide A

A member of the family of dapdiamides consisting of alanylvaline in which one of the methyl hydrogens of alanine is replaced by a fumaramoyl group.


gamma-glutamyl-beta-cyanoalanine

A dipeptide composed of 3-cyano-L-alanine and L-glutamine joined by a peptide linkage formed from the side-chain of glutamine.


Ser-Pro

A dipeptide formed from L-serine and L-proline residues.


Ile-Val

A dipeptide formed from L-isoleucine and L-valine residues.


Gln-Gly

A dipeptide formed from L-glutamine and glycine residues.


isoechinulin B anion

Major microspecies at pH 7.3.


A member of the class of 2,5-diketopiperazines that is piperazine substituted by oxo groups at positions 2 and 5, and by a methyl group at position 3.


A dipeptide consisting of N-butyl-L-alaninamide having an (R)-2-amino-2-(4-hydroxyphenyl)acetyl residue attached to its alpha-amino nitrogen.


Trp-Pro

A dipeptide obtained by formal condensation of the carboxy group of L-tryptophan with the amino group of L-proline.


Val-Ala

A dipeptide formed from L-valine and L-alanine residues.


KYOTORPHIN

A dipeptide composed of L-tyrosine and L-arginine joined by a peptide linkage.


Met-Tyr

A dipeptide formed from L-methionine and L-tyrosine residues.


Leu-His

A dipeptide formed from L-leucine and L-histidine residues.


His-Pro

A dipeptide formed from L-histidine and L-proline residues.


Phe-Lys

A dipeptide obtained by formal condensation of the carboxy group of L-phenylalanine with the amino group of L-lysine.


Val-Leu

A dipeptide formed from L-valine and L-leucine residues.


Pro-Trp

A dipeptide formed from L-proline and L-tryptophan residues.


Ile-Phe

A dipeptide formed from L-isoleucine and L-phenylalanine residues.


Pro-Ala

A dipeptide formed from L-proline and L-alanine residues.


Lys-Arg

A dipeptide formed from L-lysine and L-arginine residues.


Trp-Glu

A dipeptide formed from L-tryptophan and L-glutamic acid residues.


A non-proteinogenic dipeptide anion formed from the (3R)-hydroxylation of L-gamma-glutamyl-L-propargylglycine(1-). Major species at pH 7.3.


Trp-Tyr

A dipeptide formed from L-tryptophan and L-tyrosine residues.


Gly-Gln

A dipeptide formed from glycine and L-glutamine residues.


Leu-Arg

A dipeptide composed of L-leucine and L-arginine joined by peptide linkages.


Gly-Met

A dipeptide formed from glycine and L-methionine residues.


Phe-FMDP

A dipeptide composed of 3-{[(2E)-4-methoxy-4-oxobut-2-enoyl]amino}alanine and L-phenylalanine joined by peptide linkages.


L-tryptophan polyoxin C

Polyoxin C in which the primary amino group has been condensed with L-tryptophan to form a peptide bond.


Leu-Lys

A dipeptide composed of L-leucine and L-lysine joined by a peptide linkage.


7-dimethylallyl isoechinulin B anion

Major microspecies at pH 7.3.


His-Lys

A dipeptide formed from L-histidine and L-lysine residues.


Asp-His

A dipeptide composed of L-aspartic acid and L-histidine joined by a peptide linkage.


beta-Asp-Ile

A dipeptide that is the N-(L-beta-aspartyl) derivative of L-isoleucine.


Dnp-Nor-Gln

A dipeptide consisting of L-norvaline substituted on nitrogen by a 2,4-dinitrophenyl group and connected to L-glutamine via a peptide bond.


cyclo(L-tyrosyl-L-phenylalanyl)

A member of the class of 2,5-diketopiperazines that is piperazine-2,5-dione in which one hydrogen at position 3 and one hydrogen at position 6 are replaced by benzyl and 4-hydroxybenzyl groups (the 3S,6S-diastereomer).


Arg-Val

A dipeptide formed from L-arginine and L-valine residues.


His-Ile

A dipeptide obtained by formal condensation of the carboxy group of L-histidine with the amino group of L-isoleucine.


A dipeptide consisting of a modified L-proline residue attached to L-alanine via a peptide linkage.


D-gamma-glutamyl-D-glutamic acid

A dipeptide consisting of a D-gamma-glutamyl residue attached to D-glutamic via a peptide linkage.


Gly-Thr

A dipeptide formed from glycine and L-threonine residues.


NAAG

A dipeptide composed of N-acetyl-L-aspartic acid and L-glutamic acid joined by a peptide linkage.


Asp-Tyr

A dipeptide composed of L-aspartic acid and L-tyrosine joined by a peptide linkage.


cyclo(L-phenylalanyl-L-leucyl)

A member of the class of 2,5-diketopiperazines that is piperazine-2,5-dione in which one hydrogen at position 3 and one hydrogen at position 6 are replaced by benzyl and isobutyl groups (the 3S,6S-diastereomer).


Cys-Arg

A dipeptide obtained by formal condensation of the carboxy group of L-cysteine with the amino group of L-arginine.


A dipeptide consisting of L-phenylalanine nitro-substituted at C-4 of the phenyl ring and connected to L-glutamine via a peptide bond.


glioperazine B

A member of the class of 2,5-diketopiperazines with an indole substituent. It is a microbial metabolite isolated from the mycelia of a liquid fermentation culture of the fungus, Bionectria byssicola and has been shown to exhibit antibacterial activity against Staphylococcus aureus.


Gly-Lys

A dipeptide formed from glycine and L-lysine residues.


Ala-Ile

A dipeptide formed from L-alanyl and L-isoleucine residues.


VAL-VAL

A dipeptide formed from two L-valine residues.


fellutanine

A member of the class of  2,5-diketopiperazines that is piperazine-2,5-dione substituted by 1H-indol-3-ylmethyl groups at positions 3 and 6 respectively. Isolated from  Penicillium species, it exhibits antibacterial activity.


Leu-Phe

A dipeptide formed from L-leucine and L-phenylalanine residues.


Ser-Ser

A dipeptide formed from two L-serine residues.


Tyr-Ile

A dipeptide formed from L-tyrosine and L-isoleucine residues.


TRYPROSTATIN A

A cyclic dipeptide that is brevianamide F (cyclo-L-Trp-L-Pro) substituted at positions 2 and 6 on the indole ring by prenyl and methoxy groups respectively.


Phe-beta-Ala

A dipeptide formed from L-phenylalanine and beta-alanine residues.


Asn-Gly

A dipeptide composed of L-asparagine and glycine joined by a peptide linkage.


L-Lys-D-Glu

A dipeptide obtained by formal condensation of the carboxy group of L-lysine with the amino group of D-glutamic acid. It is a constituent of bacterial peptidoglycan type A4alpha.


Ser-Phe

A dipeptide that is the N-(L-seryl) derivative of L-phenylalanine.


Phe-Val

A dipeptide formed from L-phenylalanine and L-valine residues.


Met-Asn

A dipeptide obtained by formal condensation of the carboxy group of L-methionine with the amino group of L-asparagine.


Lys-Trp

A dipeptide formed from L-lysine and L-tryptophan residues.


Arg-Trp

A dipeptide formed from L-arginine and L-tryptophan residues.


beta-Ala-Ala

A dipeptide formed from beta-alanine and L-alanine residues.


Gln-Gln

A dipeptide formed from two L-glutamine residues.


Ala-His

A dipeptide formed from L-alanyl and L-histidine residues.


perindoprilat

A dipeptide obtained by formal condensation of one of the carboxy groups of N-[(1S)-1-carboxyethyl]-L-norvaline with the amino group of (2S,3aS,7aS)-octahydroindole-2-carboxylic acid. The major active metabolite of perindopril.


Asp-Lys

A dipeptide formed from L-alpha-aspartyl and L-lysine residues.


Asn-Phe

A dipeptide obtained by formal condensation of the carboxy group of L-asparagine with the amino group of L-phenylalanine.


gamma-Glu-Met

A dipeptide composed of L-glutamic acid and L-methionine joined by a peptide linkage.


Gly-Val

A dipeptide formed from glycine and L-valine residues.


Thr-Val

A dipeptide obtained by formal condensation of the carboxy group of L-threonine with the amino group of L-valine.


Thr-Trp

A dipeptide composed of L-threonine and L-tryptophan joined by a peptide linkage.


Major microspecies at pH 7.3.


L-gamma-Glu-L-Thr

A dipeptide obtained by formal condensation of the side-chain carboxy group of L-glutamic acid with the amino group of L-threonnine.


ficellomycin

A dipeptide antibiotic containing an azabicyclohexane ring system that exhibits potent in vitro activity against Penicillium oxalicum and Staphylococcus aureus. It inhibits semi-conservative DNA replication by causing accumulation of 34S DNA species.


Ser-Lys

A dipeptide composed of L-serine and L-lysine joined by a peptide linkage. It is a constituent of bacterial cell wall peptidoglycan type A11.14 and A3alpha.


Gly-Cys

A dipeptide formed from glycine and L-cysteine residues.


gamma-glutamylphenylalanine

A dipeptide composed of glutamic acid and phenylalanine joined together by a peptide linkage.


Thr-Asp

A dipeptide formed from L-threonine and L-aspartic acid residues.


L-glutamylglycine 2-naphthylamide

An N-(2-naphthyl)carboxamide obtained by formal condensation of the C-terminal carboxy group of L-glutamylglycine with the amino group of 2-naphthylamine.


Dnp-Thr-Gln

A dipeptide consisting of L-threonine substituted on nitrogen by a 2,4-dinitrophenyl group and connected to L-glutamine via a peptide bond.


Gly-Glu

A dipeptide formed from glycyl and L-glutamic acid residues.


Gln-Glu

A dipeptide formed from L-glutamine and L-glutamic acid residues.


Asp-Ser

A dipeptide composed of L-aspartic acid and L-serine joined by a peptide linkage.


beta-Ala-Phe

A dipeptide formed from beta-alanine and L-phenylalanine residues.


Ile-Leu

A dipeptide formed from L-isoleucine and L-leucine residues.


glycyl-L-phenylalanine 2-naphthylamide

An N-(2-naphthyl)carboxamide obtained by formal condensation of the carboxy group of glycyl-L-phenylalanine with the amino group of 2-naphthylamine.


Tyr-Tyr

Tyrosyltyrosine in which each tyrosine residue has L-configuration.


Thr-Phe

A dipeptide formed from L-threonine and L-phenylalanine residues.


neotame

A dipeptide composed of N-(3,3-dimethylbutyl)-L-aspartic acid and methyl L-phenylalanate units joined by a peptide linkage.


pyroglutamylvaline

A dipeptide obtained by formal condensation of the carboxy group of pyroglutamic acid with the amino group of valine.


gamma-Glu-Gln

A dipeptide obtained by formal condensation of the gamma-carboxy group of glutamic acid with the amino group of glutamine


Tyr-Asp

A dipeptide obtained by formal condensation of the carboxy group of L-tyrosine with the amino group of L-aspartic acid.


BREVIANAMIDE F

A pyrrolopyrazine that is hexahydropyrrolo[1,2-a]pyrazine-1,4-dione bearing an indol-3-ylmethyl substituent at position 3 (the 3S,8aS-diastereomer, obtained by formal cyclocondensation of L-tryptophan and L-proline).


A dipeptide composed of N-acetyl-L-phenylalanine and 3,5-diiodo-L-tyrosine joined together by a peptide linkage. It is a synthetic substrate for pepsin.


Val-Pro

A dipeptide formed from L-valine and L-proline residues.


Glu-Lys

A dipeptide composed of L-glutamic acid and L-lysine joined by a peptide linkage.


L-cysteinylglycine

A dipeptide consisting of glycine having an L-cysteinyl attached to its alpha-amino group. It is an intermediate metabolite in glutathione metabolism.


Glu-Gly

A dipeptide composed of L-glutamic acid and glycine joined by a peptide linkage.


Leu-beta-Ala

A dipeptide formed from L-leucine and beta-alanine residues.


Thr-Lys

A dipeptide obtained by formal condensation of the carboxy group of L-threonine with the amino group of L-lysine.


Val-Thr

A dipeptide obtained by formal condensation of the carboxy group of L-valine with the amino group of L-threonine.


L-gamma-glutamyl-L-cysteine

A molecular entity formed when L-cysteine amino group binds to the gamma-carbonyl of L-glutamic acid.


cyclo(L-tyrosyl-L-tyrosyl)

A cyclo(tyrosyl-tyrosyl) in which both stereocentres have L-configuration. Synthesized by Mycobacterium tuberculosis.


Thr-Tyr

A dipeptide composed of L-threonine and L-tyrosine joined by a peptide linkage.


Pro-Hyp

A dipeptide composed of L-proline and L-hydroxyproline residues. It is a biomarker for bone collagen degradation.


Glu-Gln

A dipeptide obtained by formal condensation of the carboxy group of L-glutamic acid with the amino group of L-glutamine.


trandolapril

A heterobicylic compound that is (2S,3aR,7aS)-1-[(2S)-2-aminopropanoyl]octahydro-1H-indole-2-carboxylic acid in which the hydrogen of the amino group is substituted by a (2R)-1-ethoxy-1-oxo-4-phenylbutan-2-yl group. It is a angiotensin-converting enzyme inhibitor and a prodrug used for the treatment of hypertension.


Phe-Gly

A dipeptide formed from L-phenylalanine and glycine residues.


ALBONOURSIN

A member of the class of 2,5-diketopiperazines that is piperazine-2,5-dione in which the two hydrogen at position 3 and those at position 6 are replaced by benzylidene and isobutylidene groups (the 3Z,6Z-geoisomer).


Major species at pH 7.3.


Arg-Met

A dipeptide formed from L-arginine and L-methionine residues.


Ser-Gln

A dipeptide formed from L-serine and L-glutamine residues.


Met-Arg

A dipeptide formed from L-methionine and L-arginine residues.


Pro-Ser

A dipeptide formed from L-proline and L-serine residues.


Lys-Glu

A dipeptide formed from L-lysine and L-glutamic acid residues.


Thr-Leu

A dipeptide formed from L-threonine and L-leucine residues.


Glu-Ile

A dipeptide obtained by formal condensation of the carboxy group of L-glutamic acid with the amino group of L-isoleucine.


L-Orn-D-Glu

A dipeptide obtained by formal condensation of the carboxy group of L-ornithine with the amino group of D-glutamic acid. It is a constituent of bacterial peptidoglycan type A4beta.


Trp-Trp

A dipeptide formed from two L-tryptophan residues.


Met-Gln

A dipeptide formed from L-methionine and L-glutamine residues.


Trp-Asn

A dipeptide obtained by formal condensation of the carboxy group of L-tryptophan with the amino group of L-asparagine.


cyclo(dehydrophenylalanyl-L-leucyl)

A member of the class of 2,5-diketopiperazines that is piperazine-2,5-dione in which two hydrogen at position 3 and one hydrogen at position 6 are replaced by benzylidene and isobutyl groups respectively.


maculosin

A  homodetic cyclic peptide that is a dipeptide composed of L-proline and L-tyrosine joined by peptide linkages.


Thr-Ala

A dipeptide formed from L-threonine and L-alanine residues.


Tyr-Pro

A dipeptide obtained by formal condensation of the carboxy group of L-tyrosine with the amino group of L-proline.


Val-Lys

A dipeptide formed from L-valine and L-lysine residues.


PROTUBONINE B

An acetate ester obtained by the formal condensation of the hydroxy group of the fungal metabolite  protubonine A with acetic acid. It has been isolated from Aspergillus species.


Lys-Tyr

A dipeptide formed from L-lysine and L-tyrosine residues.


enalapril

A dicarboxylic acid monoester that is ethyl 4-phenylbutanoate in which a hydrogen alpha to the carboxy group is substituted by the amino group of L-alanyl-L-proline (S-configuration).


Tyr-Ala

A dipeptide formed from L-tyrosine and L-alanine residues.


L-arginyl-L-glutamic acid

A dipeptide comprising L-arginine with a L-glutamic acid residue attached to the N(1) nitrogen.


Ile-Ser

A dipeptide formed from L-isoleucine and L-serine residues.