ARDISIANOSIDES A

A triterpenoid saponin that is composed of (3beta,16alpha)-13,28-epoxyoleanane-3,16-diol having a  beta-D-Glcp-(1->2)-{beta-D-Xylp-(1->2)-{beta-D-Glcp-(1->3)-[beta-D-Glcp-(1->4)]-beta-D-Glcp-(1->3)}-beta-D-Glcp-(1->4)}-alpha-L-Arap moiety attached to position 3 by a glycosidic linkage. It is isolated from whole plants of Ardisia japonica and exhibits significant cytotoxicity against a panel of human cancer cell lines.


ditrans,polycis-dodecaprenyl phosphate

A polyprenol phosphate having twelve prenyl units in the chain (the 2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34Z,38E,42E-isomer).


kadlongilactone B

A hexacyclic triterpenoid isolated from the leaves and stems of Kadsura longipedunculata and has been found to exhibit cytotoxicity aganist human tumour cells.


sinularolide E

A cembrane diterpenoid isolated from Sinularia gibberosa and has been shown to exhibit antineoplastic activity.


gibberosin K

A  diterpenoid of the xeniaphyllane type isolated from Sinularia gibberosa and has been shown to exhibit  antineoplastic activity.


SECOLOGANIN

An iridoid monoterpenoid that is acetaldehyde in which on of the hydrogens of the methyl group has been replaced by a 2-(beta-D-glucopyranosyloxy)-3,4-dihydro-2H-pyran-4-yl group which is substituted at positions 3 and 5 by a vinyl and a methoxycarbonyl group, respectively (the 2S,3R,4S stereoisomer).


AJUGACILIATIN B

A diterpene lactone isolated from the whole plants of Ajuga ciliata and has been shown to exhibit neuroprotective activity.


beta-AMYRIN

A pentacyclic triterpenoid that is oleanane substituted at the 3beta-position by a hydroxy group and containing a double bond between positions 12 and 13. It is one of the most commonly occurring triterpenoids in higher plants.


The (1S,2R,4R)-isomer of cinflubrolin.


A tetracyclic triterpenoid that is dammarane with an exocyclic double bond at C-25 and substituent hydroxy groups at positions 3, 6, 12, 20, 22 and 24 (the  3beta,6alpha,12beta,24S stereoisomer). It is isolated from the leaves of Panax ginseng and exhibits cytotoxicity in the human hepatoma cell line, HepG2.


fumagillol

A sesquiterpenoid with antimicrobial properties.


corianin

A sesquiterpene lactone containing an epoxide group and two tertiary hydroxy groups that has been isolated from the fruits of Coriaria ruscifolia and Coriaria japonica.


An optically active form of 1-hydroxylimonen-2-one having (1R,4S)-configuration.


sodorifen

A carbobicyclic compound that is bicyclo[3.2.1]oct-6-ene which is substituted by a methylene group at position 3 and by methyl groups at the 1,2,4,5,6,7, and 8-anti positions. It is the major volatile component released by the rhizobacterium Serratia odorifera.


AJUGAMARIN A1

A  diterpene lactone isolated from the whole plants of Ajuga ciliata.


A decaprenyl diphosphate having (Z)-stereochemistry about all but one of the double bonds.


A polyprenyl glycosyl phosphate consisting of alpha-D-abequosyl-(1->3)-alpha-D-mannosyl-(1->4)-alpha-L-rhamnosyl-(1->3)-beta-D-galactose attached at the 1-position to decaprenyl phosphate.


ma'ilione

A sesquiterpenoid isolated from the marine red algae, Laurencia scoparia.


A carotenol having the structure of 1,1',2,2'-tetrahydro-psi,psi-carotene with hydroxy functions at the 1 and 1' positions.


CYCLOLAUDENOL (24S)

A pentacyclic triterpenoid that is (24S)-methyl-9beta,19-cyclolanost-25-ene which carries a hydroxy group at position 3beta. It is isolated from several plant species inclduing Turraeanthus  and Tillandsia.


hedychilactone D

A labdane diterpenoid that is 7,11,13-labdatrien-16,15-olide substituted by a hydroxy group at position 7 and an oxo group at position 6. Isolated from the rhizomes of Hedychium spicatum, it exhibits cytotoxicity against the Colo-205 (Colo-cancer), A-431 (skin cancer), MCF-7 (breast cancer), A-549 (lung cancer) and Chinese hamster ovary cells (CHO).


lancifodilactone G

A triterpenoid that is a nortriterpenoid isolated from Schisandra lancifolia and has been shown to exhibit anti-HIV activity.


A hopanoid that is hopane substituted by a hydroxy group at position 22.


A scalarane sesterterpenoid isolated from the marine sponge Hyrtios erectus that exhibits antineoplastic activity.


bicycloelemene

A carbobicyclic compound that is 7,7-dimethylbicyclo[4.1.0]heptane substituted by prop-1-en-2-yl, ethenyl and methyl groups at positions 2, 3 and 3, respectively (the 1R,2R,3S,6R-stereoisomer). It is a sesquiterpene isolated from the leaves of several plant species.


heptaprenyl diphosphate

A polyprenol diphosphate compound having seven prenyl units with undefined stereochemistry about the double bonds.


(+)-kolavenyl diphosphate

A diterpenyl phosphate that is the O-diphospho derivative of (+)-kolavenol


LAXIRACEMOSIN H

A  terpene alkaloid with a tirucallane skeleton isolated from Dysoxylum lenticellatum.


capsanthin 5,6-epoxide

A epoxycarotenol that is capsanthin in which the 5,6-double bond has been epoxidised.


all-trans-dodecaprenyl diphosphate

An all-trans-polyprenyl diphosphate composed from twelve isoprenyl units.


nardoperoxide

A sesquiterpenoid that is 1,4,5,6,7,8-hexahydro-4,7-epidioxyazulen-3(2H)-one substituted by a hydroxy group at position 8, methyl groups at positions 1 and 4 and an isopropyl group at position 7 (the (1R,4R,7R,8R stereoisomer). Isolated from Nardostachys chinensis, it exhibits antimalarial activity.


gutolactone

A  quassinoid isolated from Simaba guianensis and has been shown to exhibit antimalarial activity.


RUBUSOSIDE

A steviol glycoside that is steviol in which both the carboxy group and the tertiary allylic hydroxy group have been converted to their corresponding beta-D-glucosides. A precious bioactive natural sweetener which mainly exists the in Chinese sweet tea plant, Rubus suavissimus.


dihydromyrcenol

A monoterpenoid that is oct-7-en-2-ol substituted by methyl groups at positions 2 and 6 respectively.


triptobenzene K

A tetracyclic diterpenoid with formula C20H22O5, originally isolated from the dried root outer bark of Tripterygium hypoglaucum.


cyclosativene

A sesquiterpene.


(+)-eremophilene

A member of the classs of octahydronaphthalenes and a sesquiterpene that is 1,2,3,4,4a,5,6,7-octahydronaphthalene which is substituted by an isopropenyl group at position 3 and by methyl groups at positions 4a and 5 (the 3S,4aS,5R- diastereoisomer).


ETHYL LANSIOLATE

A triterpenoid that is the ethyl ester of lansiolic acid. It has been isolated from the twigs of Lansium domesticum.


preaustinoid A1

A  meroterpenoid found in Penicillium rubrum and Penicillium species. It has been found to exhibit inhibitory activity against the production of interleukin 1-beta from induced inflammasomes.


drimenol

A sesquiterpenoid primary alcohol, being methanol in which one of the methyl hydrogens is substituted by a 2,5,5,8a-tetramethyl-1,4,4a,5,6,7,8,8a-octahydronaphthalen-1-yl group.


A taxane diterpenoid that is taxusin in which the hydrogen at the 7beta position is replaced by a hydroxy group.


nezukol

An isopimarane diterpenoid that is isopimarane in which the ethyl subtituent at position 13 has undergone formal dehydrogenation to the corresponding vinyl group, and in which the hydrogen at position 8 has been replaced by a hydroxy group. It has been found in the leaves of several plants, including Cryptomeria japonica and Isodon rubescens.


alpha-amyrin

A pentacyclic triterpenoid that is ursane which contains a double bond between positions 12 and 13 and in which the hydrogen at the 3beta position is substituted by a hydroxy group.


A cembrane diterpenoid isolated from Lobophytum and shown to have anti-HIV-1 activity.


CRASSICAULINE A

A diterpene alkaloid with formula C35H49NO10 that is isolated from several Aconitum species.


anisotanol A

A norsesquiterpenoid with formula C14H24O3. It is isolated from Anisodus tanguticus.


A retinoid that is all-trans-3,4-didehydroretinol in which the double bond alpha- to the the terminal hydroxy group has been reduced to a single bond.


ASCARIDOLE

A p-menthane monoterpenoid that is p-menth-2-ene with a peroxy group across position 1 to 4.


nonadecaprenyl diphosphate

A polyprenol diphosphate compound having nineteen prenyl units with undefined stereochemistry about the double bonds.


colossolactone VII

A tricyclic triterpenoid that is 3,4-seco-lanosta-8,24-diene-26,22-olide 3-methylester substituted by an acetoxy group at position 19 and a hydroxy group at position 4. It is isolated from the fruiting bodies of the Vietnamese mushroom Ganoderma colossum and displays inhibitory activity towards the enzyme HIV protease.


A carotenoid ether that is spirilloxanthin carrying two hydroxy groups, both at position 2.


AJUGAMARIN A1 CHLOROHYDRIN

A diterpene lactone isolated from the whole plants of Ajuga ciliata.


A diterpenoid that is ent-cassa-12,15-diene carrying oxo and hydroxy substituents at positions 2 and 3beta respectively.


A  quassinoid that is the 15-O-acetyl derivative of bruceolide. It has been isolated from Brucea javanica and Brucea sumatrana.


triptophenolide methyl ether

A tetracyclic diterpenoid with formula C21H26O3, originally isolated from Tripterygium wilfordii.


cornusalterin A

A tirucallane triterpenoid that is (13alpha,14beta,17alpha,20S,23E)-lanosta-7,23-diene substituted by a beta-hydroxy group at position 3 and a methoxy group at position 25. It has been isolated from the stem and stem barks of Cornus walteri.


delta-elemene

A sesquiterpene that is cyclohexene that is substituted at positions 1, 3, 4, and 4 by isopropyl, isopropenyl, methyl, and vinyl groups, respectively (the R,R stereoisomer).


alpha-selinene

An isomer of selinene where the double bond in the octahydronaphthalene ring system is endocyclic (2R,4aR,8aR)-configuration..


VERRUCARIN A

A trichothecene antibiotic which incorporates a triester macrocyclic structure and an exocyclic methylene epoxide group.


albaflavenone

A carbotricyclic compound that is (+)-epi-isozizaene in which the hydrogens at position 5 have been replaced by an oxo group.


A member of the class of carotenone that is echinenone carrying an additional hydroxy substituent at position 4'.


A terpenyl phosphate obtained by hydroxylation of one of the terminal methyl groups of (2E,6E)-farnesyl diphosphate


tripterifordin

A kaurane diterpenoid that is (5beta,8alpha,13alpha)-18,20-epoxykauran-18-one substituted by a hydroxy group at position 16. Isolated from the roots of Tripterygium wilfordii, it exhibits anti-HIV activity.


TASUMATROL F

A taxane diterpenoid isolated from Taxus sumatrana and has been shown to exhibit antineoplastic activity.


A triterpenoid that is squalene substituted at position 12 by a hydroxy group (the R-enantiomer).


A diterpenoid that is the 3alpha-hydroxy-11-oxo derivative of ent-cassa-12,15-diene.


3-O-ACETYLNORCAESALPININ A

A diterpenoid isolated from the seed kernels of Caesalpinia crista that has been found to exhibit antimalarial activity.


A tricyclic diterpenoid that is 15,16-epoxydolabrene in which the pro-S hydrogen at position 3 has been replaced by a hydroxy group.


An alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc(PP-Dol) in which the anomeric centre has alpha-configuration.


(2S,4S)-rose oxide

A rose oxide in which both of the stereocentres have S configuration. It is also known as (+)-trans-rose oxide.


A pentacyclic triterpenoid that is hopane in which a hydrogen attached to C-29 is replaced by a 2-hydroxyethyl group.


A (6E)-nerolidol in which the hydroxy group at positon 3 adopts an S-configuration.


A sesquiterpene that is cedrane which has a double bond between positions 8 and 9.


all-trans-retinyl heptanoate

An all-trans-retinyl ester obtained by formal condensation of the carboxy group of heptanoic acid with the hydroxy group of all-trans-retinol.


A selinene that is decahydronaphthalene substituted by a isopropenyl group at position 7, a methyl group at position 4a and a methylidene group at position 1.


zeinoxanthin

A carotenol, the structure of which is (6'R)-beta,epsilon-carotene hydroxy-substituted at C-3 with R-stereochemistry.


sinularolide D

A cembrane diterpenoid isolated from Sinularia gibberosa and has been shown to exhibit antineoplastic activity.


(+)-alpha-longipinene

The (1R,2S,7R,8R)-enantiomer of alpha-longipinene.


celastolide

A hexacyclic triterpenoid with formula C30H46O5, originally isolated from Tripterygium hypoglaucum.


capilliposide B

A triterpenoid saponin that consists of anagalligenin A substituted by a caproyl group at position 22 and a beta-D-xylopyranosyl-(1->2)-beta-D-glucopyranosyl-(1->4)-[beta-D-glucopyranosyl-(1->2)]-alpha-L-arabinopyranosyl moiety at position 3 via a glycosidic linkage. It is isolated from the whole plants of Lysimachia capillipes and has been shown to exhibit potent cytotoxicity against human A-2780 cells.


trichanolide

A  limonoid based on a mexicanolide-type skeleton isolated from Trichilia connaroides.


cyathatriol

A tricyclic diterpenoid with formula C20H32O3. It is produced by the bird's nest fungus Cyathus earlei.


cis-benzylideneacetone

The cis-isomer of benzylideneacetone.


SESTERSTATIN 2

A scalarane sesterterpenoid isolated from the marine sponge Hyrtios erectus and has been shown to exhibit antineoplastic activity.


ALPHA-ELEMOL

A sesquiterpenoid that is isopropanol which is substituted at position 2 by a (3S,4S)-3-isopropenyl-4-methyl-4-vinylcyclohexyl group.


drimendiol

A member of the class of octahydronaphthalenes that is drimenol in which a hydrogen of the allylic methyl group has been replaced by a hydroxy group.


epizonarene

A sesquiterpene that is (8aR)-1,2,3,7,8,8a-hexahydronaphthalene which is substituted at positions 2 and 5 by methyl groups and at position 8 by an isopropyl group (the 1R,8aS-diastereoisomer).


valerianol

A member of the class of octahydronaphthalenes that is 1,2,3,4,6,7,8,8a-octahydronaphthalene which is substituted by methyl groups at the 8 and 8a positions, and by a 2-hydroxypropan-2-yl group at position 2 (the 2R,8R,8aS stereoisomer).


An eremophilane sesquiterpenoid that is (+)-5-epi-aristolochene carrying an additional 1beta-hydroxy substituent.


ERYTHRODIOL

A pentacyclic triterpenoid that is beta-amyrin in which one of the hydrogens of the methyl group at position 28 has been replaced by a hydroxy group. It is a plant metabolite found in olive oil as well as in Rhododendron ferrugineum and other Rhododendron species.


A polyprenyl glycosyl phosphate consisting of alpha-D-mannosyl-(1->4)-alpha-L-rhamnosyl-(1->3)-beta-D-galactose attached at the 1-position to decaprenyl phosphate.


LAMESTICUMIN C

A triterpenoid of the class of onoceranoid-type terpenoids isolated from the twigs of Lansium domesticum.


AJUGACUMBIN A

A diterpene lactone isolated from the whole plant of Ajuga ciliata.


pinocarveol

A  pinane monoterpenoid that is a bicyclo[3.1.1]heptane substituted by two methyl groups at position 6, a methylidene group at position 2 and a hydroxy group at position 3.


alpha-benzoyloxypaeoniflorin

A monoterpene glycoside with formula C30H32O13, originally isolated from Paeonia suffruticosa.


DIACETYLVILASININ

A limonoid found in Azadirachta indica.


name: I' -(6"-0-myristyl-p-glucopyanosyloxy) -3,4,3', 4' -tetradehydro1,2,1',2'-tetrahydro-l-hydroxy-yl,yl-carotene


name: 1'-(6"-0-(I I " '-methyllauryl) -P-glucopyranosyloxy]-3,4,3',4'-tetradehydro-1,2,1',2'-tetrahydro-I -hydroxy-yl, yl-carotene


presqualene diphosphate

A triterpenyl phosphate that is presqualene in which the hydroxy hydrogen has been replaced by a diphosphate group.


bruceanol D

A quassinoid natural product found in Brucea antidysenterica consisting of a heteropentacyclic skeleton containing a delta-lactone moiety which is substituted at the alpha-carbon by a (2E)-3,4-dimethylpent-2-enoyloxy group. It shows significant in vitro cytotoxicity towards several human tumour cell lines.


all-trans-retinyl ester

A retintinyl ester in which all double bonds of the retinyl side-chain have trans-configuration.


all-trans-polyprenol phosphate

A polyprenol phosphate in which all the C=C double bonds have trans (E) configuration.


rubiarboside G 28-al

A triterpenoid saponin with an arborinane-type terpenoid as the aglycone. It has been isolated from the roots of Rubia yunnanensis.


A dehydrovomifoliol that has R-configuration at the chiral centre.


NORCAESALPININ E

A diterpenoid isolated from the seed kernels of Caesalpinia crista that has been found to exhibit antimalarial activity.


An edaxadiene in which the carbon bearing the hydroxy group has S configuration.


chlorobactene

A carotenoid that is 1,2,4-trimethylmenzene in which the hydrogen at position 3 has been replaced by an all-trans-3,7,12,16,20,24-hexamethylpentacosa-1,3,5,7,9,11,13,15,17,19,23-undecaen-1-yl group. Found in photosynthetic green bacteria.


(+)-homalomenol A

A sesquiterpenoid that is perhydroindane which is substituted by a (2-methylprop-1-en-1-yl) group at position 1, methyl groups at positions 3a and 7, and hydroxy groups at positions 4 and 7 (the 1R,3aR,4R,7S,7aR stereoisomer).


A sesterterpenoid that is 4-oxocyclohexa-1,5-diene-1-carboxylic acid carrying three additional methyl substituents at positions 2, 3 and 5 as well as farnsyl and hydroxy substituents at positions 3 and 6 respectively. An intermediate in the biosynthesis of terretonin.


beta-cubebene

A tricyclic sesquiterpene, a constituent of the leaf oil cubebene obtained from a variety of species of flowering plant.


A sesquiterpene that is 1,2,3,3a,4,5,6,8a-octahydroazulene carrying methyl, methylidene and isopropyl substituents at positions 1, 4 and 7 respectively.


triptonoterpenol

A tricyclic diterpenoid having formula C21H30O4, originally isolated from Tripterygium wilfordii.


sterebin L

A labdane diterpenoid with formula C21H36O4, originally isolated from the seeds of Oryza sativa.


A cembrane diterpenoid that is cembra-2E,7E,11Z-trien-20,10-olide substituted by hydroxy groups at positions 1 and 4. It has been isolated from the leaves of Croton gratissimus.


name: Astaxanthin diglucoside/ Astaxanthin beta-D-diglucoside


A carotenoid ether that is spheroidene substituted at position 2 by a hydroxy group.


The 9-cis-stereoisomer of violaxanthin.


oxypaeoniflorin

A monoterpene glycoside with formula C23H28O12, isolated from several species of Paeoniae.


A neoxanthin in which all of the double bonds have trans geometry except for that at the 9' position, which is cis.


gibberellin A8-catabolite

A tetracyclic diterpenoid obtained by catabolism of gibberellin A8.


CUMINGIANOSIDE D

A triterpenoid saponin that is 13,30-cyclodammar-25-ene-3,7,23,24-tetrol esterified to the corresponding acetate at position 3 and attached to a 6-O-acetyl-beta-D-glucopyranosyl residue at position 7 via a glycosidic linkage. Isolated from Dysoxylum cumingianum, it exhibits antileukemic activity.


(-)-helminthogermacrene

The (-)-isomer of helminthogermacrene.


A carotenol that is 3,4-didehydrolycopene carrying two hydroxy substituents at positions 1 and 1'.


(S)(+)CARVONE

A carvone having (S) configuration.


A polyprenyl glycosyl phosphate consisting of beta-D-ribose-5-phosphate attached at the 1-position to trans,octacis-decaprenyl phosphate via a glycosyl phosphate linkage.


luzonial B

An iridoid monoterpenoid that is hexahydro-1H-cyclopenta[c]furan substituted by hydroxy groups at positions 1 and 3a, a 3-oxopropen-2yl group at position 6 and a cis-4-coumaroyloxy moiety at position 4 (the 1S,3aS,4S,6S,6aS stereoisomer). Isolated from the leaves of Viburnum luzonicum, it exhibits antineoplastic activity.


violaxanthin

An epoxycarotenol that is 5,5',6,6'-tetrahydro-5,6:5',6'-diepoxy-beta,beta-carotene substituted by hydroxy groups at positions 3 and 3'. It is the naturally occurring xanthophyll pigment found in a variety of plants.


fucoxanthin

An epoxycarotenol that is found in brown seaweed and which exhibits anti-cancer, anti-diabetic, anti-oxidative and neuroprotective properties.


astragaloside I

A triterpenoid saponin that is cycloastragenol glycosylated at positions 3 and 6 by 2,3-di-O-acetyl-beta-D-xylosyl and beta-D-glucosyl residues respectively.


nerol oxide

A member of the class of pyrans that is 3,6-dihydro-2H-pyran which is substituted at positions 2 and 4 by a 2-methylprop-1-en-1-yl group and a methyl group, respectively.


A tricyclic diterpenoid with formula C22H34O4. It is produced by the bird's nest fungus Cyathus earlei.


(S)-linalool

The (S)-enantiomer of linalool.


terpene ketone

Any terpenoid which contains a keto group.


OPHIOBOLIN A

A sesterterpenoid that is ophiobolane with a hydroxy group at position 3, oxo groups at positions 5 and 25, double bonds at positions 7-8 and 19-20, and an oxygen link between positions 14 and 18.


triptohypol D

A pentacyclic triterpenoid with formula C32H54O2, originally isolated from the root bark of Tripterygium hypoglaucum.


An undecaprenyldiphospho-N-acetylmuramoyl peptide in which the peptide moiety is L-alanyl-D-isoglutaminyl-N(6)-pentaglycyl-L-lysyl-D-alanyl-D-alanine.


hexadecaprenyl diphosphate

A polyprenol diphosphate compound having sixteen prenyl units with undefined stereochemistry about the double bonds.


name: Zeaxanthin diglucoside/ Zeaxanthin beta-D-diglucoside


An alpha-D-Glc-(1->2)-alpha-D-Glc-(1->3)-alpha-D-Glc-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc(PP-Dol) in which the anomeric centre has alpha-configuration.


COMBRETANONE G

A pentacyclic triterpenoid that is 9beta,19-cyclolanost-25-ene substituted by an oxo group at position 3, a hydroxy group at position 7 and a methoxy group at position 25. It has been isolated from the leaves of Combretum quadrangulare.


diterpenoid

Any terpenoid derived from a diterpene. The term includes compounds in which the C20 skeleton of the parent diterpene has been rearranged or modified by the removal of one or more skeletal atoms (generally methyl groups).


(+)-beta-caryophyllene

A beta-caryophyllene in which the stereocentre adjacent to the exocyclic double bond has R configuration while the remaining stereocentre has S configuration. It is the enantiomer of (-)-beta-caryophyllene, which occurs much more widely than the (+)-form.


A carotenol that is 1',2'-dihydro-beta,psi-carotene which carries a hydroxy group at position 1'.


(+)-phytocassane B

A phytocassane that is (+)-phytocassane C which has been substituted with an additional hydroxy group at the 2alpha position.


A pentacyclic triterpenoid that is lupan-30-al with a hydroxy substituent at position 28 and an oxo group at position 3 (the 20R stereoisomer) . Isolated from  Acacia mellifera, it exhibits cytotoxicity activity against the NSCLC-N6 cell line, derived from a human non-small-cell bronchopulmonary carcinoma.


peregrinol

A labdane diterpenoid that is labdane which has been hydroxylated at position 5 of the decalin ring and in which the 3-methylpentyl substituent (also at position 5 of the decalin ring) has been dehydrogenated to introduce a trans double bond at the 3-4 position and hydroxylated at position 5.


benzoylhypaconine

A diterpene alkaloid with formula C31H43NO9 that is isolated from several Aconitum species.


An oligosaccharide phosphate that is a pentasaccharide consisting of one glucuronic acid, two mannose and two glucose residues linked via a diphospho group to undecaprenol.


lactucaxanthin

A tunaxanthin that consists of epsilon,epsilon-carotene bearing hydroxy substituents at positions 3 and 3' (the 3S,3'S,6S,6'S-diastereomer).


viteagnusin D

A labdane diterpenoid resulting from the formal allylic rearrangement of the allylic hydroxy group of peregrinol.


(-)-epicubenol

A sesquiterpenoid that is (8aS)-1,2,3,4,4a,5,6,8a-octahydronaphthalene substituted by an isopropyl group at position 1, methyl groups at positions 4 and 7, and by a hydroxy group at position 4a (the 1S,4R,4aS,8aR-diastereoisomer).


A triterpenoid saponin with hederagenin as the sapogenin. It has been isolated from the stem bark of Kalopanax pictus.


A bicyclic sesquiterpene with formula C15H24 which is biosynthesised from farnesyl diphosphate by a diterpene cyclase enzyme from Dictyostelium discoideum.


undecaprenyl diphosphate

A polyprenol diphosphate compound having eleven prenyl units with undefined stereochemistry about the double bonds.


EUPAHELIANGOLIDE A

A sesquiterpene lactone of the heliangolide group isolated from Eupatorium kiirunense and exhibits cytotoxicity against human oral epidermoid (KB), cervical epitheloid (Hela) and liver (hepa59T/VGH) carcinoma cells.


DILOPHOLIDE

A diterpenoid isolated from the brown alga Dilophus ligulatus and has been shown to exhibit cytotoxic activity.


SCOPARIC ACID A

A diterpenoid isolated from Scoparia dulcis and has been shown to exhibit inhibitory activity against beta-glucuronidase from bovine liver.


(-)-LIMONENE

An optically active form of limonene having (4S)-configuration.


alpha-copaene

A sesquiterpene that is tricyclo[4.4.0.0(2,7)]dec-3-ene bearing an isopropyl substituent at position 8 and two methyl substituents at positions 1 and 3 (the 1S,6S,7S,8S-diastereomer).


gamma-muurolene

A sesquiterpene that is 1,2,3,4,4a,5,6,8a-octahydronaphthalene which is substituted at positions 1, 4 and 7 respetively by isopropyl, methylene and methyl groups (the 1S,4aS,8aR-diastereoisomer).


A pentacyclic triterpenoid that is olean-18-ene substituted by a beta-hydroxy group at position 3 and oxo group at position 1. It has been isolated from the leaves and twigs of Juglans sinensis.


sophoradiol

A pentacyclic triterpenoid that is oleanane substituted by hydroxy groups at the 3beta and 22beta positions and containing a double bond between positions 12 and 13.


A 3beta-sterol that is lanosterol carrying a hydroxy group at position 26.


steviol glycoside

A diterpene glycoside derived from steviol by formal esterification of the carboxy group with glucose (or a glucose derivative) and glycosylation of the tertiary hydroxy group with combinations of glucose and rhamnose to give the corresponding glycosides.


alpha-bergamotene

A sesquiterpene consisting of a bicyclo[3.1.1]hept-2-ene skeleton substituted at positions 2 and 6 by methyl groups and at position 6 by a 4-methylpent-3-en-1-yl group.


oleoyl neocryptotanshinone

A diterpenoid with a fatty acyl side chain isolated from Salvia miltiorrhiza and has been shown to inhibit platelet aggregation induced by arachidonic acid.


L-CARVONE

A carvone having (R) configuration.


A thujane monoterpenoid in which which a (1R,4S,5S)-thujane skeleton is substituted at C-3 with a hydroxy group, with the new asymmetric centre at C-3 having R-configuration.


michaolide H

A cembrane diterpenoid with cytotoxic activity isolated from the soft coral Lobophytum michaelae.


lyratol C

An sesquiterpenoid that is decahydronaphthalene substituted by hydroxy groups at positions 1 and 2, a methyl group at position 8a, a methylidene group at position 4 and a 1,2-dihydroxypropan-2-yl at position 6 (the 1R,2R,4aR,6S,8aS stereoisomer) . Isolated from Solanum lyratum, it exhibits cytotoxicity against human cancer cell lines.


atisine

A organic heterohexacyclic compound and diterpene alkaloid isolated from Aconitum anthora. In solution, it is a 2:1 mixture of readily interconvertible epimers at position 20 (the carbon attached to both the nitrogen and an oxygen atom).


labdane diterpenoid

Any diterpenoid with a labdane skeleton.


epi-cedrol

The 8S-epimer of cedrol.


astacene

A carotenone that consists of beta,beta-carotene bearing four oxo substituents at positions 2, 2', 4 and 4'.


marianoside A

A triterpene glycoside that is lanost-8-ene substituted by hydroxy groups at positions 25 and 28, a methylidene group at position 24 and a beta-D-glucopyranosyloxy group at position 3. Isolated from the whole plant of Silybum marianum, it exhibits inhibitory activity against chymotrypsin.


2-hydroxyrubiarbonone E

A pentacyclic triterpenoid of the class of arborinane-type terpenoids isolated from the roots of Rubia yunnanensis.


arabidiol

A tricyclic triterpenoid that is perhydro-1H-cyclopenta[a]naphthalene that is substituted bu methyl groups at positions 3a, 6, 6, and 9a, by a hydroxy group at position 7, and by a (2R,5E)-2-hydroxy-6,10-dimethylundeca-5,9-dien-2-yl group at position 3 (the     3R,3aR,5aR,7S,9aR,9bR-isomer).


A polyprenyl phospho oligosaccharide that consists of a beta-D-Gal-(1->4)-alpha-D-GlcNAc moiety linked via a diphospho group to ditrans,octacis-undecaprenol.


NIMBIN

A limonoid found in Azadirachta indica.


triterpenoid saponin

A terpene glycoside in which the terpene moiety is a triterpenoid.


isomultiflorenol

A pentacyclic triterpenoid that is oleanan-3-ol lacking the methyl group at position 8, which has a double bond between positions 8 and 9, and which is substituted by an alpha-methyl group at position 13.


A scalarane sesterterpenoid that is 12-epi-scalarin in which the hydorxy group at position 19 is replaced by a methoxy group. It has been isolated from the sponge, Hyattella species.


nephthene

A sesquiterpene.


A  germacranolide that is the 2beta-methoxy-2-deethoxy derivative of phantomolin. Isolated from Elephantopus mollis, it exhibits antineoplastic activity.


deoxyaconitine

A diterpene alkaloid with formula C34H47NO10 that is isolated from several Aconitum species.


name: (10S)-Juvenile hormone III diol phosphate


A labdane diterpenoid that is peregrinol in which one of the hydrogens of the methyl group attached to the double bond has been replaced by a hydroxy group.


undecaprenyl dihydrogen phosphate

The all-trans-isomer of undecaprenyl phosphate.


A pentacyclic triterpenoid that is a bisnortriterpene isolated from Salacia madagascariensis and exhibits antileishmanial and antileukemic activities.


T-CADINOL

A cadinane sesquiterpenoid that is cadin-4-ene carrying a hydroxy substituent at position 10.


conidiogenone

A diterpenoid with formula C20H32O2. It is isolated from Penicillium cyclopium and exhibits potent conidiation inducing activity.


ASPERACULIN A

A sesquiterpene lactone isolated from Aspergillus aculeatus.


docosaprenyl diphosphate

A polyprenol diphosphate compound having twenty-two prenyl units with undefined stereochemistry about the double bonds.


GANODERONE A

A tetracyclic triterpenoid that is 5alpha-lanosta-8,24-diene substituted by a hydroxy group at position 26 and oxo groups at positions 3 and 7. Isolated from the fruiting bodies of Ganoderma pfeifferi, it exhibits against herpes simplex virus.


abscisic acids

Any apo carotenoid sesquiterpenoid that is 3-methylpenta-2,4-dienoic acid substituted at position 5 by a 1-hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-en-1-yl group and in which the acyclic double bond between positions 4 and 5 has E-configuration.


A germacrane sesquiterpenoid obtained from germacrane by hydroxylation at C(11) together with dehydrogenation across the C(1)-C(10) and C(5)-C(6) bonds.


decaprenyl diphosphate

A polyprenol diphosphate compound having ten prenyl units with undefined stereochemistry about the double bonds.


An apo carotenoid monoterpenoid that is alpha-ionone with a hydroxy substituent at position 3.


michaolide A

A cembrane diterpenoid with cytotoxic activity isolated from the soft coral Lobophytum michaelae.


An undecaprenyldiphospho-N-acetylmuramoyl peptide in which the peptide moiety is L-alanyl-D-isoglutaminyl-N(6)-triglycyl-L-lysyl-D-alanyl-D-alanine.


A sesquiterpenoid that is cedr-8(15)-ene substituted by a hydroxy group at position 9.


A diterpenoid that is ent-cassa-12,15-diene in which the hydrogen at position 3beta has been replaced by a hydroxy group.


(+)-endo-beta-bergamotene

A sesquiterpene consisting of a bicyclo[3.1.1]heptane skeleton substituted at position 2 by a methylidene group and at position 6 by methyl and 4-methylpent-3-en-1-yl groups (the all-S diastereoisomer).


barbinine

A diterpene alkaloid that is a phytotoxin produced by several Delphinium species.


(+)-(S)-ar-turmerone

A sesquiterpenoid that is 2-methylhept-2-en-4-one substituted by a 4-methylphenyl group at position 6. It has been isolated from Peltophorum dasyrachis.


(2S)-2-hydroxyphytanic acid

A 20-carbon, methyl-branched hydroxy fatty acid and intermediate in phytanic acid degradation; accumulates in patients with peroxisimal disorders.


(-)-alpha-cuprenene

A sesquiterpene that consists of cyclohexa-1,3-diene bearing a methyl substituent at position 1 and an (S)-1,2,2-trimethylcyclopent-1-yl group at position 4.


all-trans-4,18-dihydroxyretinoic acid

A retinoid that consists of all-trans-retinoic acid bearing two hydroxy substituents at positions 4 and 18.


CARDIVIN B

A germacranolide isolated from the aerial parts of Carpesium divaricatum. It exhibits cytotoxicity against the human tumor cells, A-549 (nonsmall cell lung), SK-OV-3 (ovary), SK-MEL-2 (skin), XF-498 (central nervous system) and HCT-15 (colon).


(+)-thujopsene

A thujopsene that has (R,R,R)-configuration.


(+)-alpha-barbatene

A carbotricyclic compound and sesquiterpene that is 1,2,3,3a,4,5,8,8a-octahydro-4,8-methanoazulene that is substituted by methyl groups at the 3a, 4, 7 and 8a positions (the 3aR,4R,8R,8aS-diastereoisomer).


A dialkylglycerophosphoethanolamine in which both alkyl groups are specified as geranylgeranyl.


A sesquiterpenoid that is bisabola-2,10-diene substituted by a peroxy group between positions 2 and 10 (the 1S,4R,6R stereoisomer). Isolated from Artemisia stolonifera and Eupatorium rufescens, it exhibits antineoplastic and antiplasmodial activity.


GLOBOSTELLATIC ACIDS A

A tricyclic triterpenoid of the isomalabaricane group.


HT-2 TOXIN

A trichothecene mycotoxin that is T-2 toxin in which the acetyloxy group at position 4S has been hydrolysed to the corresponding hydroxy group. It is the major metabolite of T-2 toxin.


baruol

A tetracyclic triterpenoid that is chrysene which has been fully hydrogenated except for a double bond between the 12 and 12a positions and which is substituted by methyl groups at positions 1, 1, 4b, 6a, 8 and 10a positions, and by a 4-methylpent-3-en-1-yl group at position 8 (the 2S,4aS,4bR,6aS,8R,10aR,10bS-diastereoisomer). It has been isolated from the root bark of the Panamanian tree Maytenus blepharodes.


asperaculane G

A sesquiterpenoid that is (8aR)-1,2,3,3a,4,5,8,8a-octahydroazulene substituted by a 1-carboxyethylidene group at position 1, hydroxy groups at positions 3 and 4, and methyl groups at positions 3a and 6 (the 3R,3aR,4S,8aR-diastereomer).


A pentacyclic triterpenoid with formula C30H50O2, originally isolated from Tripterygium hypoglaucum.


lucialdehyde C

A tetracyclic triterpenoid that is lanosta-8,24-dien-26-al substituted by a beta-hydroxy group at position 3 and an oxo group at position 7. Isolated from Ganoderma lucidum and Ganoderma pfeifferi, it exhibits cytotoxic activity.


2-trans-4'-dihydroabscisic acid

An apo carotenoid sesquiterpenoid that is 2-trans-abscisic acid in which the keto group at position 4' has been reduced to the corresponding alcohol.


N-retinylidenephosphatidylethanolamine

A Schiff base obtained by formal condensation of the aldehyde group of  all-trans-retinal with the amino group of phosphatidylethanolamine.


picrotoxinin

A picrotoxane sesquiterpenoid that is 3a,4,5,6,7,7a-hexahydro-1H-indene-3,7-dicarboxylic acid which is substituted at positions 3a, 6, and 7a by methyl, isopropenyl, and hydroxy groups, respectively; in which the double bond at position 2-3 has been epoxidised; and in which the carboxy groups at positions 3 and 7 have undergone gamma-lactone formation by O-alkylation to positions 4 and 5, respectively. A component of picrotoxin.


A triterpenoid saponin that is 28-O-beta-D-glucopyranosyl derivative of 23-hydroxyursolic acid. It has been isolated from the leaves and twigs of Juglans sinensis.


aplysinoplide C

A sesterterpenoid isolated from the marine sponge Aplysinopsis digitata that exhibits cytotoxicity against P388 mouse leukemia cells.


A trichothecene mycotoxin that is deoxynivalenol acetylated on the oxygen at C-15. A skin and eye irritant, along with its 3-acetyl regioisomer and its parent deoxynivalenol it is considered among the most commonly and widely distributed cereal contaminants.


A tetradecaprenyl diphosphate having two (E)- and eleven (Z)-double bonds.


cimifoetiside A

A triterpene glycoside that consists of cimigenol attached to a beta-D-glucopyranosyl-(1->3)-beta-D-xylopyranosyl moiety at position 3 via a beta-glycosidic linkage (the 23R,24S stereoisomer). It is isolated from the aerial parts of  Cimicifuga foetida and exhibits significant immunosuppressive effect.


cannabinerolic acid

A dihydroxybenzoic acid that is olivetolic acid in which the hydrogen at position 3 is substituted by a neryl group. A biosynthetic precursor to Delta(9)-tetrahydrocannabinol, the principal psychoactive constituent of the cannabis plant.


name: myeloid differentiation primary response protein MyD88 sequence variant S34Y (human)

description: A myeloid differentiation primary response protein MyD88 (human) that has a Tyr residue at the position equivalent to Ser-34 of the amino acid sequence represented by UniProtKB:Q99836-1. Example: UniProtKB:Q99836-1, Ser-34, CHEBI:46858.


Duodenal Adenoma

category: biolink:Disease biolink:DiseaseOrPhenotypicFeature biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing

description: A circumscribed neoplasm that arises from the glandular epithelium of the duodenum. Morphologically, it is characterized by a proliferation of neoplastic glandular cells and it is associated with dysplasia. According to the growth pattern, it may be classified as tubular, villous, or tubulovillous.


Benign Periampullary Neoplasm

description: A neoplasm that arises from the periampullary region and is characterized by the absence of atypical or malignant cytological and architectural features, and absence of invasive features or metastatic potential..


name: sperm-egg fusion protein Juno isoform h2 (human)

description: A sperm-egg fusion protein Juno (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:A6ND01-2.


name: sperm-egg fusion protein Juno isoform h1 (human)

description: A sperm-egg fusion protein Juno (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:A6ND01-1.


name: bromodomain-containing protein 8 deaminated 1 (human)

description: A bromodomain-containing protein 8 (human) that has been deaminated on the residue at the position equivalent to Gln-703 of the amino acid sequence represented by UniProtKB:Q9H0E9-1. Example: UniProtKB:Q9H0E9-1, Gln-703, MOD:00685.


name: bromodomain-containing protein 8 isoform h4 (human)

description: A bromodomain-containing protein 8 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9H0E9-4.


name: bromodomain-containing protein 8 isoform h3 (human)

description: A bromodomain-containing protein 8 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9H0E9-3.


name: bromodomain-containing protein 8 isoform h1 (human)

description: A bromodomain-containing protein 8 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9H0E9-1.


name: bromodomain-containing protein 8 isoform 2 (human)

description: A bromodomain-containing protein 8 isoform 2 that is encoded in the genome of human.


Atypical Type A Thymoma

description: A rare type A thymoma displaying atypical features (hypercellularity, increased mitotic activity, and focal necrosis).


name: Pathologic Stage I Merkel Cell Carcinoma AJCC v8

description: Stage I includes: T1, N0, M0. T1: Maximum clinical tumor diameter equal to or less than 2 cm. N0: No regional lymph node metastasis detected on pathologic examination. M0: No distant metastasis detected on clinical and/or radiologic examination. (AJCC 8th ed.)


A protein that is a translation product of the human LMOD2 gene or a 1:1 ortholog thereof.


leiomodin-2 deaminated 1 (human)

A leiomodin-2 (human) that has been deaminated on the residue at the position equivalent to Gln-436 of the amino acid sequence represented by UniProtKB:Q6P5Q4-1. Example: UniProtKB:Q6P5Q4-1, Gln-436, MOD:00685.


leiomodin-2 isoform h3 (human)

A leiomodin-2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q6P5Q4-3.


leiomodin-2 isoform h1 (human)

A leiomodin-2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q6P5Q4-1.


leiomodin-2 isoform h2 (human)

A leiomodin-2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q6P5Q4-2.


leiomodin-2 phosphorylated 1 (human)

A leiomodin-2 (human) that has been phosphorylated on the residue at the position equivalent to Tyr-118 of the amino acid sequence represented by UniProtKB:Q6P5Q4-1. Example: UniProtKB:Q6P5Q4-1, Tyr-118, MOD:00048.


A trivalent inorganic anion obtained by removal of all three protons from antimonic acid.


LADD syndrome 1

description: Any LADD syndrome in which the cause of the disease is a variation in the FGFR2 gene.


name: fibronectin type 3 and ankyrin repeat domains protein 1 isoform h3 (human)

description: A fibronectin type 3 and ankyrin repeat domains protein 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8TC84-3.


prokineticin-1 isoform 1 (human)

A prokineticin-1 isoform 1 that is encoded in the genome of human.


agrin O-glycosylated 19 (human)

An agrin (human) that has been O-glycosylated at the residue equivalent to Thr-162 of the amino acid sequence represented by UniProtKB:O00468-1, in which the glycan composition is represented by GlyTouCan:G29068FM. Example: UniProtKB:O00468-1, Thr-162, MOD:00005~GNO:G29068FM.


cataract 44

description: Any early-onset non-syndromic cataract in which the cause of the disease is a mutation in the LSS gene.


name: tRNA modification GTPase GTPBP3, mitochondrial isoform h3 (human)

description: A tRNA modification GTPase GTPBP3, mitochondrial (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q969Y2-3.


heme

A heme is any tetrapyrrolic chelate of iron.


name: cis-heme d hydroxychlorin gamma-spirolactone methyl ester

description: A carboxylic ester that is the methyl ester of cis-heme d hydroxychlorin gamma-spirolactone.


heme b

A metalloprotoporphyrin in which the four pyrrole nitrogens of the protoporphyrin moiety are coordinated to iron. It is the most abundant of the heme compounds.


heme d trans-diol

A metallochlorin that is ferroheme b which is trans-dihydroxylated at positions 5 and 6.


name: cis-heme d hydroxychlorin gamma-spirolactone

description: A metallochlorin that is heme d in which the hydroxy group and the carboxy group of the 6-carboxyethyl substituent have undergone intramolecular condensation to afford the corresponding gamma-spirolactone.


heme d cis-diol

A metallochlorin that is ferroheme b which is cis-dihydroxylated at positions 5 and 6.


name: trans-heme d hydroxychlorin gamma-spirolactone

description: A metallochlorin that is ferroheme b which is hydroxylated at positions 5 and 6, and in which the resulting 6-hydroxy group undergoes formal condensation with the carboxy group of the 6-carboxyethyl group to afford the corresponding spirolactone in which the oxygen atoms at positions 5 and 6 are trans to each other.


name: endothelin-converting enzyme 1 deaminated 3 (human)

description: An endothelin-converting enzyme 1 (human) that has been deaminated on the residue at the position equivalent to Asn-660 of the amino acid sequence represented by UniProtKB:P42892-1. Example: UniProtKB:P42892-1, Asn-660, MOD:00684.


name: cadherin-related family member 1 isoform h2 (human)

description: A cadherin-related family member 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q96JP9-2.


name: cadherin-related family member 1 isoform h1 (human)

description: A cadherin-related family member 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q96JP9-1.


name: dual specificity protein kinase CLK4 phosphorylated 1 (human)

description: A dual specificity protein kinase CLK4 (human) that has been phosphorylated on the residue at the position equivalent to Tyr-303 of the amino acid sequence represented by UniProtKB:Q9HAZ1. UniProtKB:Q9HAZ1, Tyr-303, MOD:00048.


Cellular neurothekeoma

description: A nerve sheath myxoma with increased cellularity.


name: erythropoietin N-glycosylated 142 (human)

description: An erythropoietin (human) that has been N-glycosylated at the residue equivalent to Asn-65 of the amino acid sequence represented by UniProtKB:P01588-1, in which the glycan structure is represented by GlyTouCan:G48109OV. Example: UniProtKB:P01588-1, Asn-65, MOD:00160~GNO:G48109OV.


name: lysosomal proton-coupled steroid conjugate and bile acid symporter SLC46A3 isoform h2 (human)

description: A lysosomal proton-coupled steroid conjugate and bile acid symporter SLC46A3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q7Z3Q1-2.


tetraspanin-16 isoform h2 (human)

A tetraspanin-16 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9UKR8-2.


An aromatic ketone that is 2,3-dihydro-1H-inden-1-one which is substituted at positions 2, 3, and 5 by (E)-benzylidene, cyclohexylamino, and bromine, respectively. A hyperactivator of fibroblast growth factor signaling in transgenic zebrafish that is devoid of developmental toxicity and restores defective MAPK activity caused by overexpression of DUSP1 and DUSP6 in mammalian cells.


leukosialin O-glycosylated 15 (human)

A leukosialin (human) that has been O-glycosylated at the residue equivalent to Ser-29 of the amino acid sequence represented by UniProtKB:P16150-1, in which the glycan structure is represented by GlyTouCan:G00031MO. Example: UniProtKB:P16150-1, Ser-29, MOD:00002~GNO:G00031MO.


name: double-stranded RNA-specific adenosine deaminase cysteinylated 1 (human)

description: A double-stranded RNA-specific adenosine deaminase (human) that has been cysteinylated on the residue at the position equivalent to Cys-304 of the amino acid sequence represented by UniProtKB:P55265-1. Example: UniProtKB:P55265-1, Cys-304, MOD:00765.


name: double-stranded RNA-specific adenosine deaminase isoform h2 (human)

description: A double-stranded RNA-specific adenosine deaminase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P55265-2.


name: double-stranded RNA-specific adenosine deaminase methylated 1 (human)

description: A double-stranded RNA-specific adenosine deaminase (human) that has been methylated on the residue at the position equivalent to Cys-630 of the amino acid sequence represented by UniProtKB:P55265-1. Example: UniProtKB:P55265-1, Cys-630, MOD:00660.


name: double-stranded RNA-specific adenosine deaminase deaminated 1 (human)

description: A double-stranded RNA-specific adenosine deaminase (human) that has been deaminated on the residue at the position equivalent to Asn-1127 of the amino acid sequence represented by UniProtKB:P55265-1. Example: UniProtKB:P55265-1, Asn-1127, MOD:00684.


name: double-stranded RNA-specific adenosine deaminase methylated 3 (human)

description: A double-stranded RNA-specific adenosine deaminase (human) that has been methylated on the residue at the position equivalent to Arg-74 of the amino acid sequence represented by UniProtKB:P55265-1. Example: UniProtKB:P55265-1, Arg-74, MOD:00658.


name: double-stranded RNA-specific adenosine deaminase isoform h3 (human)

description: A double-stranded RNA-specific adenosine deaminase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P55265-3.


name: double-stranded RNA-specific adenosine deaminase isoform h4 (human)

description: A double-stranded RNA-specific adenosine deaminase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P55265-4.


name: double-stranded RNA-specific adenosine deaminase methylated 5 (human)

description: A double-stranded RNA-specific adenosine deaminase (human) that has been methylated on the residue at the position equivalent to Arg-114 of the amino acid sequence represented by UniProtKB:P55265-1. Example: UniProtKB:P55265-1, Arg-114, MOD:00658.


name: double-stranded RNA-specific adenosine deaminase methylated 2 (human)

description: A double-stranded RNA-specific adenosine deaminase (human) that has been methylated on the residue at the position equivalent to Cys-304 of the amino acid sequence represented by UniProtKB:P55265-1. Example: UniProtKB:P55265-1, Cys-304, MOD:00660.


name: double-stranded RNA-specific adenosine deaminase isoform 5 (human)

description: A double-stranded RNA-specific adenosine deaminase isoform 5 that is encoded in the genome of human.


name: double-stranded RNA-specific adenosine deaminase isoform 1 (human)

description: A double-stranded RNA-specific adenosine deaminase isoform 1 that is encoded in the genome of human.


name: double-stranded RNA-specific adenosine deaminase methylated 4 (human)

description: A double-stranded RNA-specific adenosine deaminase (human) that has been methylated on the residue at the position equivalent to Cys-1036 of the amino acid sequence represented by UniProtKB:P55265-1. Example: UniProtKB:P55265-1, Cys-1036, MOD:00660.


name: double-stranded RNA-specific adenosine deaminase cysteinylated 2 (human)

description: A double-stranded RNA-specific adenosine deaminase (human) that has been cysteinylated on the residue at the position equivalent to Cys-1036 of the amino acid sequence represented by UniProtKB:P55265-1. Example: UniProtKB:P55265-1, Cys-1036, MOD:00765.


name: double-stranded RNA-specific adenosine deaminase methylated 6 (human)

description: A double-stranded RNA-specific adenosine deaminase (human) that has been methylated on the residue at the position equivalent to Cys-893 of the amino acid sequence represented by UniProtKB:P55265-1. Example: UniProtKB:P55265-1, Cys-893, MOD:00660.


name: cutaneous undifferentiated pleomorphic sarcoma

description: An undifferentiated pleomorphic sarcoma arising from the skin. It is characterized by the presence of spindle cells in a storiform pattern and histiocytes with abundant cytoplasm.


name: E3 ubiquitin-protein ligase RNF38 isoform h5 (human)

description: An E3 ubiquitin-protein ligase RNF38 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9H0F5-5.


anaplastic sarcoma of the kidney

description: A kidney sarcoma that is characterized by a proliferation of anaplastic spindle cells with bizarre, pleomorphic nuclei and atypical mitotic figures.


name: C2 domain-containing protein 3 isoform h4 (human)

description: A C2 domain-containing protein 3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q4AC94-4.


5-fluoroanthranilic acid

An aminobenzoic acid that is anthranilic acid in which the hydrogen at position 5 on the phenyl ring is replaced by fluorine.


name: autosomal recessive limb-girdle muscular dystrophy type 2Q

description: Autosomal recessive limb-girdle muscular dystrophy type 2Q (LGMD2Q) is a form of limb-girdle muscular dystrophy characterized by proximal muscle weakness presenting in early childhood (with occasional falls and difficulties in climbing stairs) and a progressive course resulting in loss of ambulation in early adulthood. Muscle atrophy and multiple contractures have also been reported in rare cases.


name: leukotriene A-4 hydrolase hydroxylated 1 (human)

description: A leukotriene A-4 hydrolase (human) that has been hydroxylated on the residue at the position equivalent to Trp-425 of the amino acid sequence represented by UniProtKB:P09960-1. Example: UniProtKB:P09960-1, Trp-425, MOD:01622.


name: leukotriene A-4 hydrolase isoform h2 (human)

description: A leukotriene A-4 hydrolase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P09960-2.


name: leukotriene A-4 hydrolase isoform 1 (human)

description: A leukotriene A-4 hydrolase isoform 1 that is encoded in the genome of human.


name: leukotriene A-4 hydrolase isoform h3 (human)

description: A leukotriene A-4 hydrolase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P09960-3.


name: leukotriene A-4 hydrolase, initiator methionine removed form (human)

description: A leukotriene A-4 hydrolase (human) that has had the initiator methionine removed. UniProtKB:P09960, 2-611.


name: leukotriene A-4 hydrolase deaminated 1 (human)

description: A leukotriene A-4 hydrolase (human) that has been deaminated on the residue at the position equivalent to Asn-467 of the amino acid sequence represented by UniProtKB:P09960-1. Example: UniProtKB:P09960-1, Asn-467, MOD:00684.


name: leukotriene A-4 hydrolase isoform h4 (human)

description: A leukotriene A-4 hydrolase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P09960-4.


Gastrointestinal dysplasia

description: A finding indicating the presence of morphologic features of neoplasia in the epithelium of any part of the digestive system without evidence of invasion.  These features include architectural and cytological epithelial alterations.


Moderate dysplasia of colon

description: A morphologic finding indicating the presence of moderate dysplastic cellular changes and moderate architectural changes in the glandular epithelium of the colonic mucosa. There is no evidence of invasion.


Mild dysplasia of colon

description: A morphologic finding indicating the presence of mild dysplastic cellular changes and mild architectural changes in the glandular epithelium of the colonic mucosa. There is no evidence of invasion.


Gastric dysplasia

description: A intraepithelial neoplasia (dysplasia) that arises in either the native gastric mucosa or in metaplastic gastric epithelium.  It has a flat, polypoid or slightly depressed growth pattern.  It is graded as low grade (mild dysplasia) or high grade (moderate dysplasia and carcinoma in situ).  (WHO, 2000)


peroxisome biogenesis disorder 7B

description: An autosomal recessive condition caused by mutation(s) in the PEX26 gene, encoding peroxisome assembly protein 26. Peroxisome biogenesis disorder 7B is characterized by overlapping phenotypes of neonatal adrenoleukodystrophy and infantile Refsum disease.


name: hypoxia-inducible factor 1-alpha inhibitor cysteinylated 1 (human)

description: A hypoxia-inducible factor 1-alpha inhibitor (human) that has been cysteinylated on the residue at the position equivalent to Cys-226 of the amino acid sequence represented by UniProtKB:Q9NWT6. UniProtKB:Q9NWT6, Cys-226, MOD:00765.


dioctophymiasis

description: A disease caused by infection with Dioctophyme renale.


Enoplea infectious disease

description: Infections with nematodes of the order enoplida.


capillariasis

description: A infectious disease involving the Capillaria.


Trichinella spiralis infectious disease

description: An disease or disorder caused by infection with Trichinella spiralis.


name: heterotaxy, visceral, 10, autosomal, with male infertility


name: Ras-associated and pleckstrin homology domains-containing protein 1 isoform hRMO1 (human)

description: A Ras-associated and pleckstrin homology domains-containing protein 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q70E73-2.


name: malignant central nervous system mesenchymal, non-meningothelial neoplasm

description: A metastasizing mesenchymal, non-meningothelial neoplasm that arises from the central nervous system.


name: central nervous system melanocytic neoplasm

description: A primary tumor of the central nervous system that arises from leptomeningeal melanocytes. It may present as a diffuse proliferative leptomeningeal process (often as a component of the neurocutaneous melanosis complex) or as a distinct mass lesion.


name: central nervous system extraskeletal osteosarcoma

description: An osteosarcoma arising from the brain or spinal cord.


diencephalic cancer

description: A cancer involving a diencephalon.


name: rhabdoid tumor predisposition syndrome 2

description: Any familial rhabdoid tumor in which the cause of the disease is a mutation in the SMARCA4 gene.


cerebral sarcoma

description: A sarcoma involving a telencephalon.


name: primary intracranial sarcoma, DICER1-mutant

description: A brain sarcoma that is composed of malignant pleomorphic or spindle neoplastic cells typically demonstrating myogenic and/or chondroid differentiation. Cytoplasmic eosinophilic globules and myxoid stroma formation are usually present. It is associated with mutations in the DICER1 gene.


malignant leptomeningeal tumor

description: A primary or metastatic malignant tumor involving the leptomeninges.


skin meningioma

description: A meningioma (disease) that involves the zone of skin.


choroid plexus meningioma

description: A meningioma that affects the choroid plexus.


intraventricular meningioma

description: A meningioma that affects the ventricles of the brain.


spinal meninges cancer

description: A malignant neoplasm involving the meninx of spinal cord.


pineal gland cancer

description: Abnormal malignant growth of the cells that comprise the pineal parenchyma.


adult leptomeningeal melanoma

description: A melanoma that arises from leptomeningeal melanocytes and occurs in adulthood.


cerebral hemisphere cancer

description: A cancer that involves the cerebral hemisphere.


cerebellopontine angle embryonal tumor

description: A central nervous system embryonal tumor, not otherwise specified arising from the cerebellopontine angle of the infratentorial brain.


lateral ventricle meningioma

description: A meningioma that affects the lateral ventricle of the brain.


primary skin meningioma

description: A rare extracranial meningioma that arises from the skin.


malignant carotid body paraganglioma

description: A carotid body paraganglioma that metastasizes to other anatomic sites.


brainstem cancer

description: A primary or metastatic malignant neoplasm that affects the brain stem.


paragangliomas 5

description: Any paraganglioma in which the cause of the disease is a mutation in the SDHA gene.


frontal convexity meningioma

description: A meningioma that affects the frontal sulcus.


infratentorial cancer

description: Malignant neoplasms which arise or occur within the intracranial cavity below the tentorium cerebelli. This includes neoplasms within the brain and/or surrounding spaces.


central nervous system sarcoma

description: A sarcoma that arises from the central nervous system.


name: cerebral primitive neuroectodermal tumor

description: A central nervous system embryonal tumor, not otherwise specified arising from the cerebral hemispheres.


cancer of cerebellum

description: A cancer that involves the cerebellum.


name: intracranial extraskeletal myxoid chondrosarcoma

description: An extraskeletal myxoid chondrosarcoma arising from the structures within the cranium.


intracerebral cystic meningioma

description: A cystic meningioma that grows within the cerebral hemispheres.


cerebral ventricle cancer

description: A neoplasm that involves a brain ventricle. It may be a primary neoplasm arising from a brain ventricle, a metastasis from a distant anatomic site, or an extension of an invasive neoplasm from an adjacent brain structure.


name: embryonal tumor with multilayered rosettes

description: A rare central nervous system embryonal tumor characterized by embryonal cells arranged in multilayered rosettes and displaying one of three morphological patterns: embryonal tumor with abundant neuropil and true rosettes, ependymoblastoma, or medulloepithelioma. The tumors typically have a C19MC alteration or (rarely) a DICER1 mutation and correspond to WHO grade IV. They are mostly localized intracranially, rarely in the spinal cord, and commonly cause signs and symptoms of elevated intracranial pressure, sometimes seizures and focal neurological signs. Most cases occur in children during the first two years of life.


thalamic cancer

description: A cancer involving a dorsal plus ventral thalamus.


parietal lobe cancer

description: A malignant neoplasm involving the parietal lobe


cerebral convexity meningioma

description: A meningioma that affects the cerebral sulcus.


leptomeningeal sarcoma

description: A sarcoma arising from the leptomeninges.


brain sarcoma

description: A sarcoma arising from the brain.


diffuse meningeal melanocytosis

description: A diffuse or multifocal proliferation of uniform nevoid polygonal cells in the leptomeninges. Cells may spread into the Virchow-Robin spaces without frank invasion of the brain. Diffuse melanocytosis carries a poor prognosis even in the absence of histologic malignancy. (WHO)


central nervous system rhabdomyosarcoma

description: A malignant mesenchymal neoplasm with skeletal muscle differentiation affecting the central nervous system.


leptomeningeal melanoma

description: A melanoma that arises from leptomeningeal melanocytes.


malignant jugulotympanic paraganglioma

description: A jugulotympanic paraganglioma that metastasizes to other anatomic sites.


sarcomatosis of the meninges

description: A rare condition characterized by diffuse spread of sarcoma cells throughout the meninges. The neoplastic cells are derived from meningeal connective tissue. Clinically, this disorder may present as a fulminant pachymeningitis and/or encephalitis.


choroid plexus cancer

description: A malignant neoplasm involving the choroid plexus


paragangliomas 4

description: Any paraganglioma in which the cause of the disease is a mutation in the SDHB gene.


malignant tumor of meninges

description: A cancer that involves the meningeal cluster.


central nervous system leiomyosarcoma

description: An aggressive malignant smooth muscle neoplasm, arising from the central nervous system. It is characterized by a proliferation of neoplastic spindle cells.


paragangliomas 2

description: Any paraganglioma in which the cause of the disease is a mutation in the SDHAF2 gene.


pediatric leptomeningeal melanoma

description: A melanoma that arises from leptomeningeal melanocytes and occurs in childhood.


name: central nervous system Ewing sarcoma/peripheral primitive neuroectodermal tumor

description: A rare Ewing sarcoma/peripheral primitive neuroectodermal tumor that affects the central nervous system either as a primary dural neoplasm or by direct extension from adjacent soft tissues or bone.


name: receptor tyrosine-protein kinase erbB-2 sequence variant R896H, signal peptide removed form (human)

description: A receptor tyrosine-protein kinase erbB-2 (human) that has a His residue at the position equivalent to Arg-896 of the amino acid sequence represented by UniProtKB:P04626-1 and that has had the signal peptide removed. Example: UniProtKB:P04626-1, 23-1255, Arg-896, CHEBI:29979.


name: E3 ubiquitin-protein ligase TRIM68 methylated 1 (human)

description: An E3 ubiquitin-protein ligase TRIM68 (human) that has been methylated on the residue at the position equivalent to Cys-479 of the amino acid sequence represented by UniProtKB:Q6AZZ1-1. Example: UniProtKB:Q6AZZ1-1, Cys-479, MOD:00660.


E3 ubiquitin-protein ligase TRIM68

A tripartite motif-containing protein that is a translation product of the human TRIM68 gene or a 1:1 ortholog thereof.


name: E3 ubiquitin-protein ligase TRIM68 isoform h2 (human)

description: An E3 ubiquitin-protein ligase TRIM68 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q6AZZ1-2.


name: E3 ubiquitin-protein ligase TRIM68 isoform h1 (human)

description: An E3 ubiquitin-protein ligase TRIM68 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q6AZZ1-1.


name: E3 ubiquitin-protein ligase TRIM68 methylated 2 (human)

description: An E3 ubiquitin-protein ligase TRIM68 (human) that has been methylated on the residue at the position equivalent to Cys-31 of the amino acid sequence represented by UniProtKB:Q6AZZ1-1. Example: UniProtKB:Q6AZZ1-1, Cys-31, MOD:00660.


name: short ulna-dysmorphism-hypotonia-intellectual disability syndrome


name: paired amphipathic helix protein Sin3a deaminated 2 (human)

description: A paired amphipathic helix protein Sin3a (human) that has been deaminated on the residue at the position equivalent to Gln-55 of the amino acid sequence represented by UniProtKB:Q96ST3. UniProtKB:Q96ST3, Gln-55, MOD:00685.


retinitis pigmentosa 27

description: Any retinitis pigmentosa in which the cause of the disease is a mutation in the NRL gene.


name: mitogen-activated protein kinase-binding protein 1 methylated 1 (human)

description: A mitogen-activated protein kinase-binding protein 1 (human) that has been methylated on the residue at the position equivalent to Cys-925 of the amino acid sequence represented by UniProtKB:O60336-1. Example: UniProtKB:O60336-1, Cys-925, MOD:00660.


name: aggrecan core protein O-glycosylated 88 (human)

description: An aggrecan core protein (human) that has been O-glycosylated at the residue equivalent to Thr-2258 of the amino acid sequence represented by UniProtKB:P16112-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P16112-1, Thr-2258, MOD:00005~GNO:G43417UB.


name: snRNA-activating protein complex subunit 1

description: A protein that is a translation product of the human SNAPC1 gene or a 1:1 ortholog thereof.


phospholemman isoform 1 (human)

A phospholemman isoform 1 that is encoded in the genome of human.


phospholemman

A protein that is a translation product of the human FXYD1 gene or a 1:1 ortholog thereof.


name: phospholemman, signal peptide removed form (human)

description: A phospholemman (human) that has had the signal peptide removed. UniProtKB:O00168, 21-92.


name: protein delta homolog 1 O-glycosylated 2 (human)

description: A protein delta homolog 1 (human) that has been O-glycosylated at the residue equivalent to Thr-269 of the amino acid sequence represented by UniProtKB:P80370-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P80370-1, Thr-269, MOD:00005~GNO:G43417UB.


Procyanidin C2

A proanthocyanidin consisting of three (+)-catechin trimer joined by two successive (4alpha->8)-linkages.


Stage I Ureter Cancer AJCC v8

description: Stage I includes: T1, N0, M0. T1: Tumor invades subepithelial connective tissue. N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 8th ed.)


name: Stage I Renal Pelvis and Ureter Cancer AJCC v8


median nodule of the upper lip

description: Median nodule of the upper lip is a minor trait of the lip transmitted in an autosomal dominant fashion.


name: Charcot-Marie-Tooth disease axonal type 2S

description: Any Charcot-Marie-Tooth disease in which the cause of the disease is a mutation in the IGHMBP2 gene.


name: centrosomal protein of 152 kDa cysteinylated 1 (human)

description: A centrosomal protein of 152 kDa (human) that has been cysteinylated on the residue at the position equivalent to Cys-732 of the amino acid sequence represented by UniProtKB:O94986-4. Example: UniProtKB:O94986-4, Cys-732, MOD:00765.


ethyl decanoate

A fatty acid ethyl ester of   decanoic acid.


name: complement factor H methylated 1 (human)

description: A complement factor H (human) that has been methylated on the residue at the position equivalent to Cys-9 of the amino acid sequence represented by UniProtKB:P08603-1. Example: UniProtKB:P08603-1, Cys-9, MOD:00660.


name: histone H2A type 1-G/I/K/L/M, initiator methionine removed omega-methylated 2 (human)

description: A histone H2A type 1-G/I/K/L/M (human) that has had the initiator methionine removed and that has been omega-methylated on the residue at the position equivalent to Arg-12 of the amino acid sequence represented by UniProtKB:P0C0S8. UniProtKB:P0C0S8, 2-130, Arg-12, MOD:00078.


nicastrin deaminated 1 (human)

A nicastrin (human) that has been deaminated on the residue at the position equivalent to Asn-55 of the amino acid sequence represented by UniProtKB:Q92542-1. Example: UniProtKB:Q92542-1, Asn-55, MOD:00684.


name: WD repeat domain phosphoinositide-interacting protein 1 isoform 1 (human)

description: A WD repeat domain phosphoinositide-interacting protein 1 isoform 1 that is encoded in the genome of human.


name: CDC42 small effector protein 1 phosphorylated 2 (human)

description: A CDC42 small effector protein 1 (human) that has been phosphorylated on the residue at the position equivalent to Ser-74 of the amino acid sequence represented by UniProtKB:Q9NRR8-1. Example: UniProtKB:Q9NRR8-1, Ser-74, MOD:00046.


variola minor infection

description: A orthopoxvirus that causes a milder clinical syndrome than smallpox.


name: integrator complex subunit 10 methylated 2 (human)

description: An integrator complex subunit 10 (human) that has been methylated on the residue at the position equivalent to Cys-502 of the amino acid sequence represented by UniProtKB:Q9NVR2. UniProtKB:Q9NVR2, Cys-502, MOD:00660.


name: integrator complex subunit 10 methylated 1 (human)

description: An integrator complex subunit 10 (human) that has been methylated on the residue at the position equivalent to Cys-564 of the amino acid sequence represented by UniProtKB:Q9NVR2. UniProtKB:Q9NVR2, Cys-564, MOD:00660.


name: integrator complex subunit 10 isoform 1 (human)

description: An integrator complex subunit 10 isoform 1 that is encoded in the genome of human.


A diacylglycerol 34:5 in which the acyl groups specified at positions 1 and 2 are (9Z)-tetradecenoyl and (5Z,8Z,11Z,14Z)-icosatetraenoyl respectively.


name: transcription factor Sp1 isoform 1 cleaved 1 (human)

description: A transcription factor Sp1 isoform 1 cleaved 1 in human. UniProtKB:P08047-1, 65-785.


Y+L amino acid transporter 1

A protein that is a translation product of the human SLC7A7 gene or a 1:1 ortholog thereof.


name: Y+L amino acid transporter 1 sequence variant L334R (human)

description: A Y+L amino acid transporter 1 (human) that has an Arg residue at the position equivalent to Leu-334 of the amino acid sequence represented by UniProtKB:Q9UM01. UniProtKB:Q9UM01, Leu-334, CHEBI:29952.


name: Y+L amino acid transporter 1 sequence variant T188I (human)

description: A Y+L amino acid transporter 1 (human) that has an Ile residue at the position equivalent to Thr-188 of the amino acid sequence represented by UniProtKB:Q9UM01. UniProtKB:Q9UM01, Thr-188, CHEBI:30009.


name: Y+L amino acid transporter 1 cysteinylated 1 (human)

description: A Y+L amino acid transporter 1 (human) that has been cysteinylated on the residue at the position equivalent to Cys-151 of the amino acid sequence represented by UniProtKB:Q9UM01. UniProtKB:Q9UM01, Cys-151, MOD:00765.


name: Y+L amino acid transporter 1 sequence variant M50K (human)

description: A Y+L amino acid transporter 1 (human) that has a Lys residue at the position equivalent to Met-50 of the amino acid sequence represented by UniProtKB:Q9UM01. UniProtKB:Q9UM01, Met-50, CHEBI:29967.


name: retinoblastoma-associated protein phosphorylated 1 (human)

description: A retinoblastoma-associated protein (human) that has been phosphorylated at Ser-612. UniProtKB:P06400, Ser-612, MOD:00046.


name: PRKAR1A-Inactivated Pigmented Epithelioid Melanocytoma

description: A pigmented epithelioid melanocytoma that is associated with PRKAR1A gene inactivation.


Timothy syndrome type 2

description: Classical Timothy syndrome without cutaneous syndactyly.


long QT syndrome 9

description: Any long QT syndrome in which the cause of the disease is a mutation in the CAV3 gene.


Timothy syndrome type 1

description: Classical Timothy syndrome with cutaneous syndactyly.


long QT syndrome 10

description: Any long QT syndrome in which the cause of the disease is a mutation in the SCN4B gene.


Jervell and Lange-Nielsen syndrome 1

description: Any Jervell and Lange-Nielsen syndrome in which the cause of the disease is a mutation in the KCNQ1 gene.


long QT syndrome 6

description: Any long QT syndrome in which the cause of the disease is a mutation in the KCNE2 gene.


Timothy syndrome, atypical type

description: Atypical form of Timothy syndrome, causes a more severe form of long QT syndrome and a greater risk of arrhythmia and sudden death.


Jervell and Lange-Nielsen syndrome 2

description: Any Jervell and Lange-Nielsen syndrome in which the cause of the disease is a mutation in the KCNE1 gene.


long QT syndrome 13

description: Any long QT syndrome in which the cause of the disease is a mutation in the KCNJ5 gene.


Timothy syndrome, classic type

description: Classic form of Timothy syndrome, includes all features of generic.


name: ectopia lentis 2, isolated, autosomal recessive

description: An isolated ectopia lentis that has material basis in homozygous or compound heterozygous mutation in the ADAMTSL4 gene on chromosome 1q21.


Stage IIIC Eyelid Carcinoma AJCC v7

description: Stage IIIC includes: T4, Any N, M0.  T4: Tumor is not resectable due to extensive invasion of ocular, orbital, craniofacial structures, or brain.  M0: No distant metastasis. (AJCC 7th ed.)


Stage IIA Eyelid Carcinoma AJCC v8

description: Stage IIA includes: T2b-c, T3, N0, M0: T2b: Tumor measuring more than 10 mm but 20 mm or less in greatest dimension with invasion of the tarsal plate or eyelid margin. T2c: Tumor measuring more than 10 mm but 20 mm or less in greatest dimension involving the full thickness of the eyelid. T3: Tumor measuring more than 20 mm but 30 mm or less in greatest dimension. N0: No evidence of lymph node involvement. M0: No distant metastasis. (AJCC 8th ed.)


Stage 0 Eyelid Carcinoma AJCC v7

description: Stage 0 includes: Tis, N0, M0. Tis: Carcinoma in situ.  N0: No regional lymph node metastasis.  M0: No distant metastasis. (AJCC 7th ed.)


Stage IIIB Eyelid Carcinoma AJCC v7

description: Stage IIIB includes: Any T, N1, M0.  N1: Regional lymph node metastasis.  M0: No distant metastasis. (AJCC 7th ed.)


Stage II Eyelid Carcinoma AJCC v7

description: Stage II includes: T3a, N0, M0.  T3a: Tumor more than 20 mm in greatest dimension.  Or, any tumor that invades adjacent ocular or orbital structures.  Or, any T with perineural tumor invasion.  N0: No regional lymph node metastasis.  M0: No distant metastasis. (AJCC 7th ed.)


Stage IC Eyelid Carcinoma AJCC v7

description: Stage IC includes: T2b, N0, M0.  T2b: Tumor more than 10 mm, but not more than 20 mm in greatest dimension.  Or, tumor involves full thickness of the eyelid.  N0: No regional lymph node metastasis.  M0: No distant metastasis.  (AJCC 7th ed.)


Stage IIIB Eyelid Carcinoma AJCC v8

description: Stage IIIB includes: Any T, N2, M0. N2: Metastasis in a single ipsilateral regional lymph node, measuring more than 3 cm in greatest dimension, or in bilateral or contralateral lymph nodes. M0: No distant metastasis. (AJCC 8th ed.)


Stage I Eyelid Carcinoma AJCC v8

description: Stage I includes: IA: T1, N0, M0; IB: T2a, N0, M0. T1: Tumor measuring 10 mm or less in greatest dimension. T2a: Tumor measuring more than 10 mm but 20 mm or less in greatest dimension without invasion of the tarsal plate or eyelid margin. N0: No evidence of lymph node involvement. M0: No distant metastasis. (AJCC 8th ed.)


Basal cell carcinoma of eyelid

description: A basal cell carcinoma that arises from the eyelid.


Stage IIIA Eyelid Carcinoma AJCC v8

description: Stage IIIA includes: Any T, N1, M0. N1: Metastasis in a single ipsilateral regional lymph node, measuring 3 cm or less in greatest dimension. M0: No distant metastasis. (AJCC 8th ed.)


Stage IB Eyelid Carcinoma AJCC v7

description: Stage IB includes: T2a, N0, M0.  T2a: Tumor more than 5 mm, but not more than 10 mm in greatest dimension.  Or, any tumor that invades the tarsal plate or eyelid margin.  N0: No regional lymph node metastasis.  M0: No distant metastasis.  (AJCC 7th ed.)


Stage IV Eyelid Carcinoma AJCC v7

description: Stage IV includes: Any T, Any N, M1.  M1: Distant metastasis.  (AJCC 7th ed.)


Stage IIB Eyelid Carcinoma AJCC v8

description: Stage IIB includes: T4, N0, M0. T4: Any eyelid carcinoma invading adjacent ocular, orbital, or facial structures. N0: No evidence of lymph node involvement. M0: No distant metastasis. (AJCC 8th ed.)


Eyelid Carcinoma by AJCC v8 Stage

description: A term that refers to the staging of eyelid carcinoma according to the American Joint Committee on Cancer, 8th edition. This staging system applies to all primary carcinomas of the eyelid, including basal cell carcinoma (BCC), squamous cell carcinoma (SCC), sebaceous carcinoma, and other rare carcinomas, such as all varieties of sweat gland carcinoma (e.g., eccrine carcinoma). It does not apply to carcinomas of the head and neck with direct extension to eyelid (are staged according to the cutaneous squamous cell carcinomas of the head and neck), Merkel cell carcinomas of the eyelid (are staged according to the classification for Merkel cell carcinomas), and melanomas of the eyelid (are staged according to the classification for melanomas of the skin).  (from AJCC 8th Ed.)


Stage 0 Eyelid Carcinoma AJCC v8

description: Stage 0 includes: Tis, N0, M0. Tis: Carcinoma in situ. N0: No evidence of lymph node involvement. M0: No distant metastasis. (AJCC 8th ed.)


Stage IIIA Eyelid Carcinoma AJCC v7

description: Stage IIIA includes: T3b, N0, M0.  T3b: Complete tumor resection requires enucleation, exenteration, or bone resection.  N0: No regional lymph node metastasis.  M0: No distant metastasis. (AJCC 7th ed.)


Eyelid Carcinoma by AJCC v7 Stage

description: A term that refers to the staging of eyelid carcinoma according to the American Joint Committee on Cancer, 7th edition.


Stage IA Eyelid Carcinoma AJCC v7

description: Stage IA includes: T1, N0, M0.  T1: Tumor 5 mm or less in greatest dimension.  No invasion of the tarsal plate or eyelid margin.  N0: No regional lymph node metastasis.  M0: No distant metastasis.  (AJCC 7th ed.)


Stage II Eyelid Carcinoma AJCC v8

description: Stage II includes: IIA: T2b-c, T3, N0, M0; IIB: T4, N0, M0. T2b: Tumor measuring more than 10 mm but 20 mm or less in greatest dimension with invasion of the tarsal plate or eyelid margin. T2c: Tumor measuring more than 10 mm but 20 mm or less in greatest dimension involving the full thickness of the eyelid. T3: Tumor measuring more than 20 mm but 30 mm or less in greatest dimension. T4: Any eyelid carcinoma invading adjacent ocular, orbital, or facial structures. N0: No evidence of lymph node involvement. M0: No distant metastasis. (AJCC 8th ed.)


Stage III Eyelid Carcinoma AJCC v8

description: Stage III includes: IIIA: Any T, N1, M0; IIIB: Any T, N2, M0. N1: Metastasis in a single ipsilateral regional lymph node, measuring 3 cm or less in greatest dimension. N2: Metastasis in a single ipsilateral regional lymph node, measuring more than 3 cm in greatest dimension, or in bilateral or contralateral lymph nodes. M0: No distant metastasis. (AJCC 8th ed.)


Stage IB Eyelid Carcinoma AJCC v8

description: Stage IB includes: T2a, N0, M0. T2a: Tumor measuring more than 10 mm but 20 mm or less in greatest dimension without invasion of the tarsal plate or eyelid margin. N0: No evidence of lymph node involvement. M0: No distant metastasis. (AJCC 8th ed.)


Stage IA Eyelid Carcinoma AJCC v8

description: Stage IA includes: T1, N0, M0. T1: Tumor measuring 10 mm or less in greatest dimension. N0: No evidence of lymph node involvement. M0: No distant metastasis. (AJCC 8th ed.)


Stage IV Eyelid Carcinoma AJCC v8

description: Stage IV includes: Any T, Any N, M1. M1: Distant metastasis. (AJCC 8th ed.)


name: protein mono-ADP-ribosyltransferase PARP14 deaminated 2 (human)

description: A protein mono-ADP-ribosyltransferase PARP14 (human) that has been deaminated on the residue at the position equivalent to Gln-733 of the amino acid sequence represented by UniProtKB:Q460N5-6. Example: UniProtKB:Q460N5-6, Gln-733, MOD:00685.


name: THO complex subunit 4, initiator methionine removed form (human)

description: A THO complex subunit 4 (human) that has had the initiator methionine removed. UniProtKB:Q86V81, 2-257.


THO complex subunit 4

A protein that is a translation product of the human ALYREF gene or a 1:1 ortholog thereof.


histone H1.1

A histone H1 that is a translation product of the human H1-1 gene or a 1:1 ortholog thereof.


histone H1.1 deaminated 1 (human)

A histone H1.1 (human) that has been deaminated on the residue at the position equivalent to Asn-80 of the amino acid sequence represented by UniProtKB:Q02539. UniProtKB:Q02539, Asn-80, MOD:00684.


name: UV excision repair protein RAD23 homolog A isoform 1 (human)

description: A UV excision repair protein RAD23 homolog A isoform 1 that is encoded in the genome of human.


name: Ras and Rab interactor 3 deaminated 1 (human)

description: A Ras and Rab interactor 3 (human) that has been deaminated on the residue at the position equivalent to Gln-716 of the amino acid sequence represented by UniProtKB:Q8TB24-1. Example: UniProtKB:Q8TB24-1, Gln-716, MOD:00685.


posterior meningocele

description: Posterior meningocele is a rare neural tube closure defect characterized by the herniation of a cerebrospinal fluid-filled sac, that is lined by dura and arachnoid mater, through a posterior spina bifida and covered by a layer of skin of variable thickness, which may be dysplastic or ulcerated. The spinal cord and nerves are generally not included and function normally, although sometimes a tethered cord may be associated. They are most commonly located in the lumbar or sacral region.


true myelomeningocele

description: A rare open neural tube defect characterized by no other malformation than myelomeningocele (spina bifida with a neural placode exposed at the top of a non-epidermised dysplasic meninges sac and Chiari II malformation).


name: saccular spinal dysraphism with a stalk to the dome

description: A rare spinal dysraphism characterized by a meningocele, containing a stalk, that is attached to the inner surface of the meningocele. The stalk can be posteriorly fibroneural (saccular limited dorsal myeloschisis) or the spinal cord itself (myelic limited dorsal malformation).


hemi-myelomeningocele

description: A very rare form of composite dysraphism characterized by the presence of a split cord malformation and a myelomeningocele on one of the two hemicords. Hemicords can be in a single dural sac or in two separated dural sacs. Other spinal cord malformations can be associated. Due to the comparable prognosis it is considered as a subtype of myelomeningocele.


non-terminal myelocystocele

description: A rare closed spinal dysraphism characterized by myelocystocele located above the conus region. Also considered as a form of saccular limited dorsal myeloschisis.


name: probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase isoform h3 (human)

description: A probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P46087-3.


name: DNA damage-binding protein 1 methylated 3 (human)

description: A DNA damage-binding protein 1 (human) that has been methylated on the residue at the position equivalent to Cys-87 of the amino acid sequence represented by UniProtKB:Q16531-1. Example: UniProtKB:Q16531-1, Cys-87, MOD:00660.


papillary meningioma of the cerebellum

description: A papillary meningioma that affects the cerebellum.


name: Stage II Uterine Corpus Leiomyosarcoma AJCC v8

description: Stage II includes: T2, N0, M0. T2: Uterine corpus leiomyosarcoma with tumor extending beyond the uterus, within the pelvis. N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 8th Ed.)


An indolyl carbohydrate that is the beta-D-glucoside of 3-hydroxy-1H-indole in which the indole moiety is substituted at positions 4 and 5 by chlorine and bromine, respectively. It is used to test for the presence of an enzyme, beta-glucosidase, which cleaves the glycosidic bond to give 5-bromo-4-chloro-3-hydroxy-1H-indole, which immediately dimerises to give an intensely blue product.


An indolyl carbohydrate that is the alpha-D-glucoside of indoxyl in which the indole moiety is substituted at positions 4 and 5 by chlorine and bromine, respectively.


cyclodopa 5-beta-D-glucoside

An indolyl carbohydrate that is cyclodopa in which the phenolic hydrogen at position 5 has been replaced by a beta-D-glucosyl residue.


An indolyl carbohydrate that is the beta-D-glucuronide of indoxyl in which the indole moiety is substituted at positions 4 and 5 by chlorine and bromine, respectively


An indolyl carbohydrate that is indole-3-carboxylic acid in which the hydrogen at position 5 is replaced by a 6-O-malonyl-beta-D-glucosyloxy group.


An indolyl carbohydrate that is the alpha-D-galactoside of indoxyl in which the indole moiety is substituted at positions 4 and 5 by chlorine and bromine, respectively.


A beta-D-glucoside resulting from the formal condensation of 1-hydroxy group of beta-D-glucopyranose with the carboxy group of indole-3-butyric acid.


An indolyl carbohydrate that is the beta-D-galactosaminide of 3-hydroxy-1H-indole in which the indole moiety is substituted at positions 4 and 5 by chlorine and bromine, respectively.


D-glucosyl indole-3-carboxylate

An O-acyl carbohydrate obtained by formal condensation of the carboxy group of indole-3-carboxylic acid with the anomeric hydroxy group of D-glucose.


An indolyl carbohydrate that is 6-hydroxyindole-3-carboxylic acid in which the hydroxy group is substituted by a D-glucosyl residue.


An O-acyl carbohydrate obtained by formal condensation of the carboxy group of 6-hydroxyindole-3-carboxylic acid with the anomeric hydroxy group of D-glucose.


An indolyl carbohydrate that is the alpha-D-glucuronide of indoxyl in which the indole moiety is substituted at positions 4 and 5 by chlorine and bromine, respectively.


name: zinc finger FYVE domain-containing protein 16 methylated 2 (human)

description: A zinc finger FYVE domain-containing protein 16 (human) that has been methylated on the residue at the position equivalent to Cys-41 of the amino acid sequence represented by UniProtKB:Q7Z3T8-1. Example: UniProtKB:Q7Z3T8-1, Cys-41, MOD:00660.


name: solute carrier family 35 member E3 isoform 1 (human)

description: A solute carrier family 35 member E3 isoform 1 that is encoded in the genome of human.


name: pulmonary surfactant-associated protein A1

description: A protein that is a translation product of the human SFTPA1 gene or a 1:1 ortholog thereof.


name: pulmonary surfactant-associated protein A1 isoform h2 (human)

description: A pulmonary surfactant-associated protein A1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8IWL2-2.


name: pulmonary surfactant-associated protein A1 isoform h1 (human)

description: A pulmonary surfactant-associated protein A1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8IWL2-1.


name: pulmonary surfactant-associated protein A1, signal peptide removed form (human)

description: A pulmonary surfactant-associated protein A1 (human) that has had the signal peptide removed. UniProtKB:Q8IWL2, 21-248.


Tooth Infection

description: An infectious process affecting a tooth.


Non-Neoplastic Dental Disorder

description: A non-neoplastic disorder that affects the teeth and/or the periodontal tissues.  Representative examples include odontoma, enamel hypoplasia, and periodontitis.


Cemento-osseous dysplasia

description: A non-neoplastic fibro-osseous lesion of the tooth-bearing regions of the gnathic bones. It is characterized by a variably cellular fibrous stroma with areas of swirling and/or loose collagen. Within the stroma are mineralizing tissues consisting of osteoid, bone, and cementum-like material. As the lesions mature, they become increasingly calcified. (WHO 2017)


suppurative periapical periodontitis

description: Localized collection of pus in the tissues that enclose the root of a tooth.


Odontoma, Compound

description: A benign, slow growing, and painless hamartomatous tumor occurring in tooth-bearing areas of the jaws. It usually affects children and adolescents. It is characterized by the presence of tooth-like structures. Treatment consists of local excision. Recurrences have not been reported.


Periodontal infection

description: An infectious process affecting the tissues that surround and support the teeth.


Dental disorders congenital

description: A non-neoplastic dental disorder that is present at birth.


Dental pain and sensation disorders

description: A term that refers to disorders that result in pain and abnormal sensation in the teeth and/or periodontal tissues.


Gigantiform Cementoma

description: An extremely rare, benign, rapidly progressing fibro-osseous lesion that arises from the jaws as a multifocal expansile growth in children or adolescents. It results in significant deformity, orbital distortion, and possible airway involvement. An autosomal dominant inheritance has been proposed. Histologically, it is characterized by the presence of immature bony trabeculae and cementum-like calcifications within a hypercellular fibroblastic stroma. It shares morphological features with florid cemento-osseous dysplasia, but in florid cemento-osseous dysplasia the degree of expansion is less prominent and patients are usually older.


Periodontal Abscess

description: An acute purulent bacterial infection that arises from the tissues that surround and support the teeth.


Dental and Periodontal Infection

description: An infectious process that affects the teeth and/or the periodontal tissues.


Segmental Odontomaxillary Dysplasia

description: A developmental abnormality that is characterized by segmental enlargement in the premolar/molar region of the maxilla and associated with dento-osseous abnormalities.


Periapical Cemento-Osseous Dysplasia

description: Cemento-osseous dysplasia affecting the apical areas of mandibular anterior teeth. (WHO 2017)


Chronic pericoronitis

description: Long-term inflammation of the gingiva surrounding the crown of a tooth, usually of an incompletely erupted tooth.


Dental Developmental Disorder

description: A disorder of the teeth arising during odontogenesis.


Dental Fistula

description: Localized collection of pus in the tissues that enclose the root of a tooth and is associated with the presence of a sinus tract.


Complex odontoma

description: A benign, slow growing, and painless hamartomatous tumor occurring in tooth-bearing areas of the jaws. It is one of the most common odontogenic tumors and it usually affects children, adolescents, and young adults. It is characterized by the presence of enamel and dentin and the absence of tooth-like structures. It is treated with local excision. If it is incompletely removed, it may recur.


large ribosomal subunit protein uL23m

A protein that is a translation product of the human MRPL23 gene or a 1:1 ortholog thereof.


Hypotensive Shock

description: Shock resulting from abnormally low blood pressure.


name: brevican core protein O-glycosylated 1 (human)

description: A brevican core protein (human) that has been O-glycosylated at the residue equivalent to Thr-384 of the amino acid sequence represented by UniProtKB:Q96GW7-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:Q96GW7-1, Thr-384, MOD:00005~GNO:G43417UB.


protein GOLM2 deaminated 1 (human)

A protein GOLM2 (human) that has been deaminated on the residue at the position equivalent to Gln-129 of the amino acid sequence represented by UniProtKB:Q6P4E1-4. Example: UniProtKB:Q6P4E1-4, Gln-129, MOD:00685.


name: eukaryotic-type small ribosomal subunit protein uS15

description: A protein that is a translation product of the human RPS13 gene or a 1:1 ortholog thereof.


name: 40S ribosomal protein S13, initiator methionine removed form (human)

description: A small ribosomal subunit protein uS15 (human) that has had the initiator methionine removed. UniProtKB:P62277, 2-151.


name: small ribosomal subunit protein uS15 isoform 1 (human)

description: A eukaryotic-type small ribosomal subunit protein uS15 isoform 1 that is encoded in the genome of human.


name: E3 ubiquitin-protein ligase RNF128 isoform 1 (human)

description: An E3 ubiquitin-protein ligase RNF128 isoform 1 that is encoded in the genome of human.


nuclear factor 1 X-type

A protein that is a translation product of the human NFIX gene or a 1:1 ortholog thereof.


name: nuclear factor 1 X-type deaminated 2 (human)

description: A nuclear factor 1 X-type (human) that has been deaminated on the residue at the position equivalent to Gln-122 of the amino acid sequence represented by UniProtKB:Q14938-1. Example: UniProtKB:Q14938-1, Gln-122, MOD:00685.


name: nuclear factor 1 X-type deaminated 1 (human)

description: A nuclear factor 1 X-type (human) that has been deaminated on the residue at the position equivalent to Asn-223 of the amino acid sequence represented by UniProtKB:Q14938-1. Example: UniProtKB:Q14938-1, Asn-223, MOD:00684.


name: nuclear factor 1 X-type isoform h1 (human)

description: A nuclear factor 1 X-type (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q14938-1.


name: nuclear factor 1 X-type isoform h4 (human)

description: A nuclear factor 1 X-type (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q14938-4.


name: nuclear factor 1 X-type isoform h2 (human)

description: A nuclear factor 1 X-type (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q14938-2.


name: nuclear factor 1 X-type isoform h5 (human)

description: A nuclear factor 1 X-type (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q14938-5.


name: nuclear factor 1 X-type isoform 3 (human)

description: A nuclear factor 1 X-type isoform 3 that is encoded in the genome of human.


name: nuclear factor 1 X-type isoform h6 (human)

description: A nuclear factor 1 X-type (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q14938-6.


A UDP-amino sugar having 2,3-bis[(3R)-3-hydroxytetradecanoyl]-alpha-D-glucosamine as the amino sugar component.


A UDP-amino sugar in which the amino sugar component can be any 2,3-diacyl-alpha-D-glucosamine.


name: Vam6/Vps39-like protein isoform 1 (human)

description: A Vam6/Vps39-like protein isoform 1 that is encoded in the genome of human.


protein FAM13B isoform h2 (human)

A protein FAM13B (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9NYF5-2.


name: tissue-type plasminogen activator N-glycosylated 79 (human)

description: A tissue-type plasminogen activator (human) that has been N-glycosylated at the residue equivalent to Asn-483 of the amino acid sequence represented by UniProtKB:P00750-1, in which the glycan structure is represented by GlyTouCan:G02000AU. Example: UniProtKB:P00750-1, Asn-483, MOD:00160~GNO:G02000AU.