name: methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial sequence variant MCCA A289V (human)

description: A methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial sequence variant (human) that has a Val residue at the position equivalent to Ala-289 of the amino acid sequence represented by UniProtKB:Q96RQ3. UniProtKB:Q96RQ3, Ala-289, CHEBI:30015.


name: methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial sequence variant MCCA L437P (human)

description: A methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial sequence variant (human) that has a Pro residue at the position equivalent to Leu-437 of the amino acid sequence represented by UniProtKB:Q96RQ3. UniProtKB:Q96RQ3, Leu-437, CHEBI:50342.


name: methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial sequence variant MCCA D532H (human)

description: A methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial sequence variant (human) that lacks the region encoded by exon 13 and shifts the reading frame due to the missense mutation D532H altering the splice site at the position equivalent to Asp-532 of the amino acid sequence represented by UniProtKB:Q96RQ3.


N-acetyl-L-methionyl-L-tryptophan

A dipeptide obtained by formal condensation of the carboxy group of N-acetyl-L-methionine with the amino group of L-tryptophan.


name: AP-4 complex accessory subunit RUSC1 isoform h2 (human)

description: An AP-4 complex accessory subunit RUSC1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9BVN2-2.


name: aggrecan core protein citrullinated 1 (human)

description: An aggrecan core protein (human) that has been citrullinated on the residue at the position equivalent to Arg-305 of the amino acid sequence represented by UniProtKB:P16112-1. Example: UniProtKB:P16112-1, Arg-305, MOD:00219.


name: importin subunit alpha-7 deaminated 2 (human)

description: An importin subunit alpha-7 (human) that has been deaminated on the residue at the position equivalent to Gln-45 of the amino acid sequence represented by UniProtKB:O60684. UniProtKB:O60684, Gln-45, MOD:00685.


Prostatic Pain

category: biolink:PhenotypicFeature biolink:DiseaseOrPhenotypicFeature biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing

description: Pain in the prostate gland.


name: dTDP 1-ester with (6S)-5,6-dihydro-4-hydroxy-6-methyl-5-oxo-2H-pyran


dCDP

A 2'-deoxycytidine phosphate that is the 2'- deoxy derivative of cytidine 5'-diphosphate (CDP).


A pyrimidine 2'-deoxyribonucleoside 5'-diphosphate that is 2'-deoxycytidine 5'-diphosphate (CDP) substituted by a hydroxymethyl group at position 5.


name: 26S proteasome non-ATPase regulatory subunit 11 methylated 2 (human)

description: A 26S proteasome non-ATPase regulatory subunit 11 (human) that has been methylated on the residue at the position equivalent to Cys-202 of the amino acid sequence represented by UniProtKB:O00231-1. Example: UniProtKB:O00231-1, Cys-202, MOD:00660.


name: peptidase inhibitor 16 O-glycosylated 12 (human)

description: A peptidase inhibitor 16 (human) that has been O-glycosylated at the residue equivalent to Thr-285 of the amino acid sequence represented by UniProtKB:Q6UXB8-1, in which the glycan composition is represented by GlyTouCan:G58001LT. Example: UniProtKB:Q6UXB8-1, Thr-285, MOD:00005~GNO:G58001LT.


name: ectonucleotide pyrophosphatase/phosphodiesterase family member 2 isoform h1 (human)

description: An ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q13822-1.


name: ectonucleotide pyrophosphatase/phosphodiesterase family member 2 isoform h3 (human)

description: An ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q13822-3.


cadherin-12 isoform 1 (human)

A cadherin-12 isoform 1 that is encoded in the genome of human.


A docosanoid that is 17(R)-hydroxy-(4Z,7Z,10,12,14,19Z)-docosahexaenoic acid in which a glycinyl group is attached at position 16S via a sulfide linkage. An intermediate of specialised proresolving mediators


polyprenyl D-glucosyl phosphate

A polyprenyl glucosyl phosphate in which the glycosyl portion has D-configuration.


A polyprenyl glucosyl phosphate in which a glucosyl residue is linked to a undecaprenyl group via a diphospho group.


name: heat shock 70 kDa protein 6 deaminated 2 (human)

description: A heat shock 70 kDa protein 6 (human) that has been deaminated on the residue at the position equivalent to Asn-366 of the amino acid sequence represented by UniProtKB:P17066. UniProtKB:P17066, Asn-366, MOD:00684.


name: kinesin-like protein KIFC3 isoform h4 (human)

description: A kinesin-like protein KIFC3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9BVG8-5.


name: serine/threonine-protein kinase ULK3 isoform 1 (human)

description: A serine/threonine-protein kinase ULK3 isoform 1 that is encoded in the genome of human.


name: kinesin-like protein KIF23 cysteinylated 1 (human)

description: A kinesin-like protein KIF23 (human) that has been cysteinylated on the residue at the position equivalent to Cys-725 of the amino acid sequence represented by UniProtKB:Q02241-1. Example: UniProtKB:Q02241-1, Cys-725, MOD:00765.


name: replication protein A 70 kDa DNA-binding subunit, initiator methionine removed form (human)

description: A replication protein A 70 kDa DNA-binding subunit, initiator methionine removed form in human. UniProtKB:P27694, 2-616.


name: replication protein A 70 kDa DNA-binding subunit, initiator methionine removed sumoylated 1 (human)

description: A replication protein A 70 kDa DNA-binding subunit, initiator methionine removed form (human) that has been post-translationally modified to include sumoylated lysine at positions 449 and 577 of the amino acid sequence represented by UniProtKB:P27694. UniProtKB:P27694, 2-616, Lys-449/Lys-577, MOD:01149.


vitamin B2

Any member of a group of vitamers that belong to the chemical structural class called flavins that exhibit biological activity against vitamin B2 deficiency. Symptoms associated with vitamin B2 deficiency include glossitis, seborrhea, angular stomaitis, cheilosis and photophobia. The vitamers include riboflavin and its phosphate derivatives (and includes their salt, ionised and hydrate forms).


epithelioid cell synovial sarcoma

category: biolink:Disease biolink:DiseaseOrPhenotypicFeature biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing

description: A synovial sarcoma characterized by the presence of an epithelial cell component only. The epithelial cells are arranged in glandular or papillary structures.


name: interferon-induced, double-stranded RNA-activated protein kinase cysteinylated 1 (human)

description: An interferon-induced, double-stranded RNA-activated protein kinase (human) that has been cysteinylated on the residue at the position equivalent to Cys-485 of the amino acid sequence represented by UniProtKB:P19525-1. Example: UniProtKB:P19525-1, Cys-485, MOD:00765.


name: filamin-binding LIM protein 1 isoform h2 (human)

description: A filamin-binding LIM protein 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8WUP2-2.


name: Persistent Atrial Fibrillation by ECG Finding

description: An electrocardiographic tracing demonstrating atrial fibrillation that is present during the entire recording.


name: HLA class II histocompatibility antigen, DR beta 3 chain deaminated 1 (human)

description: An HLA class II histocompatibility antigen, DR beta 3 chain (human) that has been deaminated on the residue at the position equivalent to Gln-165 of the amino acid sequence represented by UniProtKB:P79483. UniProtKB:P79483, Gln-165, MOD:00685.


sphingomyelin 28:2

A sphingomyelin in which the total number of carbons in the sphingoid base and fatty acyl groups is 28 with 2 double bonds.


A 3-oxo Delta(4)-steroid that is testosterone carrying an additional oxo substituent at position 11.


interferon alpha-14

An interferon alpha that is a translation product of the human IFNA14 gene or a 1:1 ortholog thereof.


name: interferon alpha-14 N-glycosylated 2 (human)

description: An interferon alpha-14 (human) that has been N-glycosylated at the residue equivalent to Asn-95 of the amino acid sequence represented by UniProtKB:P01570-1, in which the glycan structure is represented by GlyTouCan:G75903TQ. Example: UniProtKB:P01570-1, Asn-95, MOD:00160~GNO:G75903TQ.


name: interferon alpha-14 N-glycosylated 1 (human)

description: An interferon alpha-14 (human) that has been N-glycosylated at the residue equivalent to Asn-95 of the amino acid sequence represented by UniProtKB:P01570-1, in which the glycan structure is represented by GlyTouCan:G07392QY. Example: UniProtKB:P01570-1, Asn-95, MOD:00160~GNO:G07392QY.


name: interferon alpha-14, signal peptide removed form (human)

description: An interferon alpha-14 (human) that has had the signal peptide removed. UniProtKB:P01570, 24-189.


catenin delta-1 isoform h1ABC (human)

A catenin delta-1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O60716-1.


name: CD14 molecule cleaved 2 GPI-anchored form (human)

description: A CD14 molecule cleaved 2 GPI-anchored form in human. UniProtKB:P08571, 20-345, Asn-345, MOD:00167.


name: platelet endothelial cell adhesion molecule isoform hDelta12 (human)

description: A platelet endothelial cell adhesion molecule (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P16284-2.


name: 3-hydroxyacyl-CoA dehydrogenase type-2 isoform h2 (human)

description: A 3-hydroxyacyl-CoA dehydrogenase type-2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q99714-2.


name: 3-hydroxyacyl-CoA dehydrogenase type-2 isoform h1 (human)

description: A 3-hydroxyacyl-CoA dehydrogenase type-2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q99714-1.


name: 3-hydroxyacyl-CoA dehydrogenase type-2, initiator methionine removed form (human)

description: A 3-hydroxyacyl-CoA dehydrogenase type-2 (human) that has had the initiator methionine removed. UniProtKB:Q99714, 2-261.


PROTHIOCONAZOLE

A racemate comprising equal amounts of (R)- and (S)-prothioconazole. A fungicide for use both as a seed treatment and foliar spray to treat a variety of diseases in cereals.


name: inhibitor of growth protein 2 sumoylated 1 (human)

description: An inhibitor of growth protein 2 (human) that has been sumoylated on the residue at the position equivalent to Lys-195 of the amino acid sequence represented by UniProtKB:Q9H160-1. Example: UniProtKB:Q9H160-1, Lys-195, MOD:01149.


name: DNA polymerase subunit gamma-1 deaminated 2 (human)

description: A DNA polymerase subunit gamma-1 (human) that has been deaminated on the residue at the position equivalent to Asn-1171 of the amino acid sequence represented by UniProtKB:P54098. UniProtKB:P54098, Asn-1171, MOD:00684.


name: DNA polymerase subunit gamma-1 deaminated 1 (human)

description: A DNA polymerase subunit gamma-1 (human) that has been deaminated on the residue at the position equivalent to Gln-262 of the amino acid sequence represented by UniProtKB:P54098. UniProtKB:P54098, Gln-262, MOD:00685.


name: cAMP-responsive element modulator isoform h11 (human)

description: A cAMP-responsive element modulator (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q03060-13.


NAD kinase cysteinylated 3 (human)

An NAD kinase (human) that has been cysteinylated on the residue at the position equivalent to Cys-69 of the amino acid sequence represented by UniProtKB:O95544-1. Example: UniProtKB:O95544-1, Cys-69, MOD:00765.


NAD kinase methylated 1 (human)

An NAD kinase (human) that has been methylated on the residue at the position equivalent to Cys-349 of the amino acid sequence represented by UniProtKB:O95544-1. Example: UniProtKB:O95544-1, Cys-349, MOD:00660.


NAD kinase cysteinylated 1 (human)

An NAD kinase (human) that has been cysteinylated on the residue at the position equivalent to Cys-180 of the amino acid sequence represented by UniProtKB:O95544-1. Example: UniProtKB:O95544-1, Cys-180, MOD:00765.


NAD kinase cysteinylated 2 (human)

An NAD kinase (human) that has been cysteinylated on the residue at the position equivalent to Cys-402 of the amino acid sequence represented by UniProtKB:O95544-1. Example: UniProtKB:O95544-1, Cys-402, MOD:00765.


NAD kinase isoform h1 (human)

An NAD kinase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O95544-1.


NAD kinase isoform h2 (human)

An NAD kinase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O95544-2.


NAD kinase deaminated 1 (human)

An NAD kinase (human) that has been deaminated on the residue at the position equivalent to Gln-195 of the amino acid sequence represented by UniProtKB:O95544-1. Example: UniProtKB:O95544-1, Gln-195, MOD:00685.


name: vacuolar protein sorting-associated protein 45 isoform h2 (human)

description: A vacuolar protein sorting-associated protein 45 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9NRW7-2.


name: U5 small nuclear ribonucleoprotein 200 kDa helicase cysteinylated 4 (human)

description: A U5 small nuclear ribonucleoprotein 200 kDa helicase (human) that has been cysteinylated on the residue at the position equivalent to Cys-1278 of the amino acid sequence represented by UniProtKB:O75643-1. Example: UniProtKB:O75643-1, Cys-1278, MOD:00765.


name: kinesin-like protein KIF15 isoform h2 (human)

description: A kinesin-like protein KIF15 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9NS87-2.


A glycotriaosylceramide having N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucose as the glycotriaosyl component.


name: DNA replication licensing factor MCM4 methylated 2 (human)

description: A DNA replication licensing factor MCM4 (human) that has been methylated on the residue at the position equivalent to Cys-306 of the amino acid sequence represented by UniProtKB:P33991. UniProtKB:P33991, Cys-306, MOD:00660.


name: DNA replication licensing factor MCM4 cysteinylated 2 (human)

description: A DNA replication licensing factor MCM4 (human) that has been cysteinylated on the residue at the position equivalent to Cys-306 of the amino acid sequence represented by UniProtKB:P33991. UniProtKB:P33991, Cys-306, MOD:00765.


name: DNA replication licensing factor MCM4 deaminated 2 (human)

description: A DNA replication licensing factor MCM4 (human) that has been deaminated on the residue at the position equivalent to Gln-257 of the amino acid sequence represented by UniProtKB:P33991. UniProtKB:P33991, Gln-257, MOD:00685.


name: DNA replication licensing factor MCM4 deaminated 1 (human)

description: A DNA replication licensing factor MCM4 (human) that has been deaminated on the residue at the position equivalent to Gln-259 of the amino acid sequence represented by UniProtKB:P33991. UniProtKB:P33991, Gln-259, MOD:00685.


name: DNA replication licensing factor MCM4 methylated 3 (human)

description: A DNA replication licensing factor MCM4 (human) that has been methylated on the residue at the position equivalent to Cys-328 of the amino acid sequence represented by UniProtKB:P33991. UniProtKB:P33991, Cys-328, MOD:00660.


name: DNA replication licensing factor MCM4 methylated 4 (human)

description: A DNA replication licensing factor MCM4 (human) that has been methylated on the residue at the position equivalent to Cys-309 of the amino acid sequence represented by UniProtKB:P33991. UniProtKB:P33991, Cys-309, MOD:00660.


name: DNA replication licensing factor MCM4 cysteinylated 1 (human)

description: A DNA replication licensing factor MCM4 (human) that has been cysteinylated on the residue at the position equivalent to Cys-328 of the amino acid sequence represented by UniProtKB:P33991. UniProtKB:P33991, Cys-328, MOD:00765.


name: DNA replication licensing factor MCM4 methylated 1 (human)

description: A DNA replication licensing factor MCM4 (human) that has been methylated on the residue at the position equivalent to Cys-162 of the amino acid sequence represented by UniProtKB:P33991. UniProtKB:P33991, Cys-162, MOD:00660.


name: DNA replication licensing factor MCM4, initiator methionine removed form (human)

description: A DNA replication licensing factor MCM4 (human) that has had the initiator methionine removed. UniProtKB:P33991, 2-863.


name: transmembrane protein 18 isoform h1 (human)

description: A transmembrane protein 18 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q96B42-1.


name: acyl-coenzyme A thioesterase 2, mitochondrial isoform h2 (human)

description: An acyl-coenzyme A thioesterase 2, mitochondrial (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P49753-2.


name: acyl-coenzyme A thioesterase 2, mitochondrial isoform h1 (human)

description: An acyl-coenzyme A thioesterase 2, mitochondrial (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P49753-1.


name: gamma-secretase subunit PEN-2 isoform 1 (human)

description: A gamma-secretase subunit PEN-2 isoform 1 that is encoded in the genome of human.


name: transcriptional-regulating factor 1 isoform h5 (human)

description: A transcriptional-regulating factor 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q96PN7-5.


name: fibroblast growth factor 16 isoform 1 (human)

description: A fibroblast growth factor 16 isoform 1 that is encoded in the genome of human.


PENNICITRINONE C

A pyranoxanthene that is 3,5-dihydro-2H-pyrano[4,3,2-kl]xanthene substituted by methyl groups at positions 2R, 3S, 4, and 10, by an oxo group at position 5, by hydroxy groups at positions 8 and 10, and by a (2S,3S)-3-hydroxybutan-2-yl group at position 9. It is a natural product isolated from the fungus Penicillium citrinum B-57.


primary hyperoxaluria type 2

description: Primary hyperoxaluria (PH) type 2 is a rare disorder of glyoxylate metabolism caused by the deficiency of the enzyme glyoxylate reductase/hydropyruvate reductase (GR/HPR) characterized by a childhood onset with clinical manifestations that include recurrent nephrolithiasis, nephrocalcinosis and end-stage renal disease with subsequent systemic oxalosis.


A member of the class of piperidine in which the hydrogen attached to the nitrogen atom is substituted by a 2-hydroxyethyl group.


name: catenin alpha-2, initiator methionine removed form (human)

description: A catenin alpha-2 (human) that has had the initiator methionine removed. UniProtKB:P26232, 2-953.


name: Disseminated varicella zoster vaccine virus infection

description: A rare systemic and life-threatening infection associated with vaccination with the live attenuated strain of the Varicella-zoster virus, Oka.


name: neutral amino acid uniporter 4 methylated 1 (human)

description: A neutral amino acid uniporter 4 (human) that has been methylated on the residue at the position equivalent to Cys-498 of the amino acid sequence represented by UniProtKB:Q6YBV0-1. Example: UniProtKB:Q6YBV0-1, Cys-498, MOD:00660.


name: neutral amino acid uniporter 4 isoform h1 (human)

description: A neutral amino acid uniporter 4 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q6YBV0-1.


name: neutral amino acid uniporter 4 isoform h2 (human)

description: A neutral amino acid uniporter 4 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q6YBV0-2.


name: cyclic AMP-dependent transcription factor ATF-6 beta isoform h2 (human)

description: A cyclic AMP-dependent transcription factor ATF-6 beta (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q99941-1.


name: Rho GDP-dissociation inhibitor 2 deaminated 1 (human)

description: A Rho GDP-dissociation inhibitor 2 (human) that has been deaminated on the residue at the position equivalent to Asn-23 of the amino acid sequence represented by UniProtKB:P52566. UniProtKB:P52566, Asn-23, MOD:00684.


name: tumor necrosis factor receptor superfamily member 3 cysteinylated 2 (human)

description: A tumor necrosis factor receptor superfamily member 3 (human) that has been cysteinylated on the residue at the position equivalent to Cys-116 of the amino acid sequence represented by UniProtKB:P36941-1. Example: UniProtKB:P36941-1, Cys-116, MOD:00765.


name: nuclear factor of activated T-cells, cytoplasmic 4 isoform h19 (human)

description: A nuclear factor of activated T-cells, cytoplasmic 4 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q14934-19.


name: E3 SUMO-protein ligase RanBP2 glutathionylated 2 (human)

description: An E3 SUMO-protein ligase RanBP2 (human) that has been glutathionylated on the residue at the position equivalent to Cys-319 of the amino acid sequence represented by UniProtKB:P49792. UniProtKB:P49792, Cys-319, MOD:00234.


Gonadal Myoid Stromal Tumor

description: A rare, benign, well-circumscribed tumor that arises from the testis. It is characterized by the presence of fascicles of spindle cells showing muscle cell differentiation. It lacks sex cord differentiation.


tuberculosis, bovine

description: An infection of cattle caused by mycobacterium bovis. It is transmissible to man and other animals.


name: ALK tyrosine kinase receptor sequence variant G881D, signal peptide removed form (human)

description: An ALK tyrosine kinase receptor (human) that has an Asp residue at the position equivalent to Gly-881 of the amino acid sequence represented by UniProtKB:Q9UM73 and that has had the signal peptide removed. UniProtKB:Q9UM73, 19-1620, Gly-881, CHEBI:29958.


name: microtubule-actin cross-linking factor 1 hydroxylated 1 (human)

description: A microtubule-actin cross-linking factor 1 (human) that has been hydroxylated on the residue at the position equivalent to Trp-316 of the amino acid sequence represented by UniProtKB:Q9UPN3-1. Example: UniProtKB:Q9UPN3-1, Trp-316, MOD:01622.


1-alkyl-sn-glycero-3-phosphate in which the alkyl substituent can be any alk-1-enyl group.


A 1-(alk-1-enyl)-sn-glycero-3-phosphate in which the alkenyl group is specified as 1Z-octadecenyl.


name: hereditary hypotrichosis with recurrent skin vesicles

description: Hereditary hypotrichosis with recurrent skin vesicles is a very rare inherited hair loss disorder described in a family and characterized by sparse, fragile or absent hair on the scalp, eyebrows, eyelashes, axillae and rest of the body, associated with vesicle formation on various parts of the scalp and body which regularly burst and release watery fluid.


name: voltage-gated potassium channel subunit beta-2 phosphorylated 1 (human)

description: A voltage-gated potassium channel subunit beta-2 (human) that has been phosphorylated on the residue at the position equivalent to Ser-266 of the amino acid sequence represented by UniProtKB:Q13303-1. Example: UniProtKB:Q13303-1, Ser-266, MOD:00046.


name: ribosomal oxygenase 2 methylated 1 (human)

description: A ribosomal oxygenase 2 (human) that has been methylated on the residue at the position equivalent to Cys-156 of the amino acid sequence represented by UniProtKB:Q8IUF8-1. Example: UniProtKB:Q8IUF8-1, Cys-156, MOD:00660.


acquired lactic acidosis

description: An instance of lactic acidosis that is acquired during the lifetime of the individual.


isoprenoid

Any lipid formally derived from isoprene (2-methylbuta-1,3-diene), the skeleton of which can generally be discerned in repeated occurrence in the molecule. The skeleton of isoprenoids may differ from strict additivity of isoprene units by loss or shift of a fragment, commonly a methyl group. The class includes both hydrocarbons and oxygenated derivatives.


A 3beta-hydroxy-4alpha-formyl-4beta-methylsteroid that is 24-methylene-9beta-9,19-cyclolanostane-3beta,28-diol in which the hydroxy group at position 28 has been oxidised to give the corresponding aldehyde.


all-trans-undecaprenol

A long-chain primary fatty alcohol that is the all-trans-isomer of undecaprenol.


GERMANICOL

A pentacyclic triterpenoid that is oleanane substituted by a hydroxy group at the 3beta-position and with a double bond between positioins 18 and 19.


(S)-citronellic acid

A citronellic acid that has (S)-configuration.


CHASMANINE

A diterpene alkaloid with formula C25H41NO6 that is isolated from several Aconitum species.


albiflorin

A monoterpene glycoside with formula C23H28O11, originally isolated from the roots of Paeonia lactiflora.


BERKELEYDIONE

A meroterpenoid found in Penicillium rubrum. It has been shown to exhibit inhibitory activity against caspase-1.


triptriolide

An abietane diterpenoid with formula C20H26O7, originally isolated from Tripterygium wilfordii.


BIXIN

A carotenoic acid that is the 6'-monomethyl ester of 9'-cis-6,6'-diapocarotene-6,6'-dioic acid.


(-)-beta-santalene

A sesquiterpene and carbobicyclic compound that is bicyclo[2.2.1]heptane in which the hydrogens at position 3 are substituted by a methylidene group, while the 2-exo- and 2-endo- hydrogens are subsitituted by 2-methylpent-2-en-5-yl and methyl groups, respectively (the 1S,2R,4R enantiomer).


The (1R,6S)-stereoisomer of cis-alpha-himachalene.


AJUGACILIATIN J

A diterpene lactone isolated from the whole plant Ajuga ciliata.


A polyprenyl glycosyl phosphate consisting of a N-acetyl-D-fucosaminyl residue attached to undecaprenyl diphosphate via a glycosyl diphosphate linkage.


A retinoid that is all-trans-retinal carrying an oxo substituent at position 4 on the cyclohexenyl ring.


neurolenin A

A germacranolide isolated from Neurolaena lobata and Austroeupatorium inulifolium and has been shown to exhibit antimalarial activity.


BETA-NOOTKATOL

A 4,4a-dimethyl-6-(prop-1-en-2-yl)-2,3,4,4a,5,6,7,8-octahydronaphthalen-2-ol with (2S,4R,4aS,6R) stereochemistry.


(+)-kolavelool

A member of the class of octahydronaphthalenes that is 1,2,3,4,4a,7,8,8a-octahydronaphthalene which is substituted at position 1 by a 3-hydroxy-3-methylpent-1-en-5-yl group and a methyl group, and by further methyl groups at positions 2, 4, and 5 (the 1R,2S,4aS,8aS stereoisomer; the stereochemistry at the tertiary alcohol was not determined).


A quassinoid that is the 3,15-di-O-propionyl derivative of bruceolide. It has been isolated from  Brucea javanica and Brucea sumatrana.


Any cucurbitacin whose C(23)-C(24) double bond has been reduced.


A triterpene glycoside that consists of 25-O-methoxycimigenol attached to a alpha-L-arabinopyranosyl residue at position 3 via a glycosidic linkage. Isolated from the rhizomes of Cimicifuga racemosa, it exhibits cytotoxic activities.


GRAYANOTOXIN I

A tetracyclic diterpenoid that is grayanotoxane in which the pro-R hydrogen at position 14 is substituted by an acetoxy group and in which the 3beta-, 5-, 6beta-, 10-, and 16- positions are substituted by hydroxy groups.


juvenile hormone III

A member of the juvenile hormone family of compounds that is the methyl ester of (2E,6E)-9-[(2R)-3,3-dimethyloxiran-2-yl]-3,7-dimethylnona-2,6-dienoic acid. Juvenile hormone III is found in most insect species.


GINSENOSIDE RB3

A ginsenoside found in Panax species that is dammarane which is substituted by hydroxy groups at the 3beta, 12beta and 20 pro-S positions, in which the hydroxy groups at positions 3 and 20 have been converted to the corresponding beta-D-glucopyranosyl-(1->2)-beta-D-glucopyranoside and beta-D-xylopyranosyl-(1->6)-beta-D-glucopyranoside respectively, and in which a double bond has been introduced at the 24-25 position.


neryl diphosphate

A polyprenol diphosphate having neryl as the polyprenyl component.


HORMINONE

An abietane diterpenoid that is abieta-8,12-diene substituted by hydroxy groups at positions 7 and 12 and oxo groups at positions 11 and 14 (the 7alpha stereoisomer) .


CABRALEONE

A  tetracyclic triterpenoid isolated from Aglaia foveolata and Aglaia abbreviata.


A dolichyl diphosphooligosaccharide in which the oligosaccharide moiety is the Man1GlcNAc2 linear trisaccharide beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc.


AJUGAPANTIN A

A diterpene lactone isolated from the whole plants of Ajuga ciliata.


APLYSINOPLIDE A

A sesterterpenoid isolated from the marine sponge Aplysinopsis digitata that exhibits cytotoxicity against P388 mouse leukemia cells.


delta-amyrin

A pentacyclic triterpenoid that is oleanane which has a double bond between positions 13 and 18, and in which the hydrogen at the 3beta position is replaced by a hydroxy group.


(+)-isoafricanol

A tricyclic sesquiterpene with formula C15H26O, that is isolated from Streptomyces violaceusniger, S. malaysiensis and Leptographium lundbergii.


alpha-farnesene

A farnesene that is 1,3,6,10-tetraene substituted by methyl groups at positions 3, 7 and 11 respectively.


ginsenoside C-K

A ginsenoside found in Panax species that is dammarane which is substituted by hydroxy groups at the 3beta, 12beta and 20 pro-S positions, in which the hydroxy group at position 20 has been converted to the corresponding beta-D-glucopyranoside, and in which a double bond has been introduced at the 24-25 position.


A cholestanoid that is 5alpha-cholesta-8,14-dien-3beta-ol bearing two additional methyl substituents at position 4.


michaolide G

A cembrane diterpenoid with cytotoxic activity isolated from the soft coral Lobophytum michaelae.


A carotenoid ether that is (3E,3'E)-1,1'-dihydroxy-3,3',4,4'-tetradehydro-1,1',2,2'-tetrahydro-psi,psi-carotene-2-one in which both hydroxyl hydrogens are substituted by methyl groups.


chloroxanthin

A carotenol obtained by formal hydration across the double bonds at position 1 of neurosporene.


An isomer of selinene where the double bond in the octahydronaphthalene ring system is endocyclic with (2S,4aR,8aR)-configuration.


ent-manool

A labdane diterpenoid in which the labdane skeleton has double bonds at positions 8(17) and 14 and carries an S-hydroxy group at position 13.


AJUGACILIATIN A

A  diterpene lactone isolated from the whole plants of Ajuga ciliata.


(+)-albicanol

A drimane-type sesquiterpenoid orginally isolated from the liverwort Diplophyllum albicans. It exhibits fish antifeedant, antifungal and antineoplastic activities.


attenoside

An acyclic diterpene glycoside consisting of a 20-hydroxygeranyllinalool skeleton conjugated to two disaccharide units at C-3 and C-20.


A polyprenyl phospho oligosaccharide consisting of undecaprenyl diphosphate and 2,3-diacetamido-2,3-dideoxy-beta-D-mannosyl-(1->3)-N-acetyl-D-fucosamine components connected by a glycosyl diphosphate linkage.


all-trans-4,16-dihydroxyretinoic acid

A retinoid that consists of all-trans-retinoic acid bearing two hydroxy substituents at positions 4 and 16.


spheroidene

The cartenoid ether that is the methyl ether of 3,4-didehydro-1,2,7',8'-tetrahydro-psi,psi-caroten-1-ol.


DISOGLUSIDE

A sterol 3-beta-D-glucoside having diosgenin as the sterol component.


rhodopin

A carotenol having the structure of 1,2-dihydro-psi,psi-carotene with a hydroxy function at C-1.


juvenile hormone I

A member of the juvenile hormone family of compounds that is the methyl ester of methyl (2E,6E,10R,11S)-10,11-epoxy-7-ethyl-3,11-dimethyl-2,6-tridecanoic acid.


neojiangyouaconitine

A diterpene alkaloid with formula C33H47NO9, originally isolated from Aconitum carmichaeli.


methyl farnesoate

A member of the juvenile hormone family of compounds that is the methyl ester of farnesoic acid. Found in several species of crustaceans.


meso-zeaxanthin

A carotenol that is beta,beta-carotene carrying two hydroxy substituents at positions 3 and 3' (the 3R,3'S-diastereomer). It is rarely found in diet and is believed to be formed at the macula by metabolic transformations of ingested carotenoids.


AJUGATAKASIN A

A diterpene lactone isolated from the whole plants of Ajuga ciliata.


alpha-cadinol

A cadinane sesquiterpenoid that is cadin-4-ene carrying a hydroxy substituent at position 10.


A triterpenoid saponin of the class of cucurbitane glycosides isolated from the roots of Machilus yaoshansis. It has been shown to exhibit inhibitory activity against  protein tyrosine phosphatase.


DYSOLENTICIN B

A  tirucallane triterpenoid  isolated from Dysoxylum lenticellatum.


A polyprenyl phospho oligosaccharide consisting of undecaprenyl diphosphate and alpha-D-rhamnosyl-(1->4)-N-acetyl-D-glucosamine components connected by a glycosyl diphosphate linkage.


lactinolide

A monoterpenoid that is hexahydro-1-benzofuran-2-one carrying two methyl substituents at positions 3 and 6 as well as two hydroxy substituents at positions 5 and 6 (the 3R,3aR,5S,6S,7aR-diastereomer).


(Z,S)-jasmolone

A beta-hydroxy ketone that is (ZZ,S)-cinerolone in which the (2Z)-but-2-en-1-yl substituent has been replaced by a (2Z)-pent-2-en-1-yl group.


gibberellin A51-catabolite

A tetracyclic diterpenoid obtained by catabolism of gibberellin A51.


triptohypol E

A pentacyclic diterpenoid with formula C31H52O2, originally isolated from the root bark of Tripterygium hypoglaucum.


forskoditerpenoside C

A diterpene glycoside that is labd-14-en-11-one substituted by beta-acetoxy group at position 6, an epoxy group between positions 8 and 13, a beta-hydroxy group at position 7 and a beta-D-glucopyranosyloxy group at position 1 (the 1alpha stereoisomer). Isolated from the whole plant of Coleus forskohlii, it shows relaxative effects on isolated guinea pig tracheal spirals in vitro.


(S)-2-trans-abscisic acid

A 2-trans-abscisic acid with (S)-configuration at the chiral centre.


A sesquiterpene lactone that is isosecotanapartholide in which the hydroxy group at position 3 is replaced by a methoxy group. Isolated from Artemisia iwayomogi and Tanacetum cilicicum, it acts as an inhibitor of nitric oxide synthase.


QUADRANOSIDE IV

A triterpenoid saponin that is the carboxylic ester obtained by the formal condensation of the carboxy group of asiatic acid with beta,23alpha-trihydroxyurs-12-en-28-oic acid 28-O-beta-D-glucopyranose. It has been isolated from Juglans sinensis.


VIBSANIN B

A vibsane diterpenoid that is (2Z,6E,10E)-cycloundeca-2,6,10-trien-1-one which is substituted at positions 2, 5, 5, 8, 9, and 9 by hydroxymethyl, methyl, 2-methylpent-2-en-5-yl, 3-methylbut-2-enoyloxy, hydroxy, and methyl groups, respectively (the 5S,8R,9R stereoisomer). It has been found to inhibit root growth in rice seedlings (IC50 0.14 mM).


PORICOIC ACID H

A tricyclic triterpenoid isolated from Poria cocos.


A diterpenoid that is ent-cassa-12,15-diene in which the hydrogen at position 2beta has been replaced by a hydroxy group.


1-EPITATRIDIN B

A germacrane sesquiterpenoid found Tanacetum vulgare that is tatridin A in which the double bond at position 9-10 has migrated to position 10-14 and in which the hydroxy group at position 1 has epimerised from alpha- to beta-.


trans-isogeraniol

An isogeraniol that has (E)-configuration.


GANODERONE C

A tetracyclic triterpenoid that is 5alpha-lanosta-8-ene with an epoxy group across positions 24 and 25, a hydroxy group at position 26 and oxo groups at positions 3 and 7. Isolated from the fruiting bodies of Ganoderma pfeifferi, it exhibits antiviral activity against influenza A virus.


limonoid

Any triterpenoid that is highly oxygenated and has a prototypical structure either containing or derived from a precursor with a 4,4,8-trimethyl-17-furanylsteroid skeleton. The term 'limonoid' comes from limonin, the first tetranortriterpenoid obtained from citrus bitter principles.


bromophycolide A

A diterpenoid that is a macrolide isolated from the Fijian red alga Callophycus serratus. It has been found to exhibit moderate cytotoxicity against several human tumour cell lines via specific apotopic cell death. It also displays anti-HIV, antibacterial, antifungal and antimalarial activity.


cis-sesquisabinene hydrate

A sesquiterpenoid that is bicyclo[3.1.0]hexane substituted by a methyl and hydroxy group at position 3 and a 2-methylhept-2-en-6-yl group at position 4.


TRICHOTHECIN

A trichothecene mycototoxin isolated from the endophytic fungus Trichothecium sp. and it exhibits anti-cancer properties.


INUMAKILACTONE

A  diterpene lactone isolated from Podocarpus latifolius and has been shown to exhibit inhibitory activity against activator protein 1 (AP-1).


A polyprenyl glucosyl phosphate in which an alpha-D-galactosyl residue is linked to a undecaprenyl group via a diphospho group.


A taxane diterpenoid that is taxane which contains double bounds at the 4-20 and 11-12 positions and which is substituted by hydroxy groups at the 5alpha and 13alpha positions.


A scalarane sesterterpenoid isolated from the marine sponge Hyrtios erectus that exhibits antineoplastic activity.


oleoside 11-methyl ester

A secoiridoid glycoside that is [(2R,3E,4S)-3-ethylidene-2-hydroxy-5-(methoxycarbonyl)-3,4-dihydro-2H-pyran-4-yl]acetic acid in which the anometric hydroxy group has been converted to the corresponding beta-D-glucoside. It has been isolated from several plant species including Olea europaea.


(2R,5S)-linalyl oxide

A monoterpenoid that is 2-(2-hydroxypropan-2-yl)oxolane carying additional methyl and vinyl substituents both located at position 5 (the 2R,5S-diastereomer).


A  tetracyclic triterpenoid found in Dysoxylum lenticellatum.


(-)-eremophilene

A member of the classs of octahydronaphthalenes and a sesquiterpene that is 1,2,3,4,4a,5,6,7-octahydronaphthalene which is substituted by an isopropenyl group at position 3 and by methyl groups at positions 4a and 5 (the 3R,4aR,5S- diastereoisomer).


AJUGAMARIN G1

A diterpene lactone isolated from the whole plant of Ajuga ciliata.


A triterpenoid saponin of the class of cucurbitane glycosides isolated from the roots of Machilus yaoshansis. It has been shown to exhibit inhibitory activity against protein tyrosine phosphatase.


OCOTILLONE

A tetracyclic triterpenoid isolated from Aglaia abbreviata.


gibberellin A110

A C20-gibberellin that is gibberellin A12 carrying an additional hydroxy substituent at the 3beta-position


A carbotricyclic compound that is 1,5-dihydro-2H-2,4a-methanonaphthalene carrying four methyl groups at positions 1,1,5, and 5.


AJUGATAKASIN B

A diterpene lactone isolated from the whole plants of Ajuga ciliata that is ajugatakasin A in which both of the 2-methylbutenoate ester goups have been hydrogenated to the corresponding 2-methylbutanoates.


all-trans-octaprenyl diphosphate

An all-trans-polyprenyl diphosphate composed from eight isoprenyl units.


all-trans-tridecaprenyl diphosphate

An all-trans-polyprenyl diphosphate composed from thirteen isoprenyl units.


KADLONGILACTONE A

A hexacyclic triterpenoid isolated from the leaves and stems of Kadsura longipedunculata and has been found to exhibit cytotoxicity aganist human tumour cells.


A pimarane diterpenoid that is pimarane which has been dehyrogenated to introduce double bonds at positions 7-8 and 15-16, which has a beta-hydrogen in place of an alpha-hydrogen at position 9, and in which one of the hydrogens of the beta-methyl group at position 4 has been replaced by a hydroxy group.


LINALOOL (+)

The (R)-enantiomer of linalool.


An acyl derivative of phosphatidic acid whose phosphorus acid component is esterified with an N-(2-hydroxyethyl)dihydropyridine bisretinoid


lansic acid 3-ethyl ester

A triterpenoid that is the 3-ethyl ester of lansic acid. It has been isolated from the twigs of Lansium domesticum.


A labdane diterpenoid resulting from the formal dehydration of the allylic hydroxy group of peregrinol.


name: 6'-Hydroxysiphonaxanthin ester/ 6'-Hydroxysiphonaxanthin dodecenoate/ 6'-Hydroxysiphonaxanthin 19-(trans-delta2-dodecenoate)


(1R,2R,3R)-prephytoene diphosphate

The (1R,2R,3R)-diastereomer of prephytoene diphosphate.


(-)-bornyl diphosphate

A monoterpenyl phosphate that is the O-diphospho derivative of (-)-borneol.


A carbotricyclic compound that is cyclooctatin in which the hydroxymethyl substituent has been reduced to the corresponding methyl group. It is the biosynthetic precursor of cyclooctatin.


carotene

Hydrocarbon carotenoids.


A polyprenyl glycosyl phosphate consisting of beta-D-ribose attached at the 1-position to trans,octacis-decaprenyl phosphate.


7-deoxyloganic acid

A cyclopentapyran that is 1,4a,5,6,7,7a-hexahydrocyclopenta[c]pyran-4-carboxylic acid substituted at positions 1 and 7 by beta-D-glucosyloxy and methyl groups respectively (the 1S,4aS,7S,7aR-diatereomer).


A polyprenyl glycosyl phosphate having eleven prenyl units and 4-amino-4-deoxy-alpha-L-arabinopyranosyl as the glycosyl moiety.


loganetin

An iridoid monoterpenoid that is methyl (4aS,7aR)-1,4a,5,6,7,7a-hexahydrocyclopenta[c]pyran-4-carboxylate substituted at positions 1 and 6 by hydroxy groups and at postion 7 by a methyl group; the aglycone of loganin.


CAMELLIOL C

A triterpenoid that is 4,6,6-trimethylcyclohex-3-en-1-ol which is substituted at position 5 by a (3E,7E,11E)-3,8,12,16-tetramethylheptadeca-3,7,11,15-tetraen-1-yl group, originally isolated from the nonsaponifiable lipids of sasanqua oil (Camellia sasanqua).


CUMINGIANOSIDE E

A triterpenoid saponin that is 24,25-epoxy-13,30-cyclodammarane-3,7,23-triol esterified to the corresponding acetate at position 3 and attached to a 6-O-acetyl-beta-D-glucopyranosyl residue at position 7 via a glycosidic linkage. Isolated from Dysoxylum cumingianum it exhibits antileukemic activity.


all-trans-nonaprenyl diphosphate

A nonaprenyl diphosphate where all C=C double bonds have (E)-configuration.


cyclooctatin

A diterpenoid characterized by a 5-8-5 dodecahydrodicyclopenta[a,d]cyclooctene fused-ring system, with a single double bond and one isopropyl, two hydroxy, one hydroxymethyl and two methyl substituents.


(+)-neoisodihydrocarveol

The (1R,2S,5R)-stereoisomer of dihydrocarveol.


A  cembrane diterpenoid that is cembra-2E,7E,11Z-trien-20,10-olide substituted by a hydroxy group at position 1 and a methoxy group at position 4. It has been isolated from the leaves of natural product found in Croton gratissimus.


A pentacyclic triterpenoid that is hopane in which a hydrogen attached to C-29 is replaced by a 2-hydroxyethyl group and in which the stereochemistry at C-17 is inverted to 17alphaH.


ARDISIANOSIDE E

A triterpenoid saponin that is (3beta,16alphaalpha)-13,28-epoxyoleanane-3,16,30-triol with a beta-D-Glcp-(1->2)-[beta-D-Glcp-(1->4)]-alpha-L-Arap moiety attached to position 3 by a glycosidic linkage. It is isolated from Ardisia japonica and exhibits anticancer properties.


ixerochinolide

A sesquiterpene lactone isolated from  Ixeris chinensis and has been shown to exhibit cytotoxic activity against human PC-3 tumor cells.


12-O-deacetyltrichilin H

A limonoid isolated from the ripe fruits of Melia azedarach.


13-cis-retinyl hexadecanoate

A retinyl ester obtained by formal condensation of the carboxy group of hexadecanoic acid with the hydroxy group of 13-cis-retinol.


A cembrane diterpenoid isolated from Lobophytum hedleyi and Lobophytum. It exhibits anti-HIV-1 activity.


A carbobicyclic compound that is 1,2,3,4,4a,5-hexahydronaphthalene which is substituted at position 1 by a propan-2-yl group and at positions 4 and 7 by methyl groups (the 1R,4R,4aS-diastereoisomer).


KANSUIPHORIN B

A tetracyclic diterpenoid that is 6,7-epoxy-13-hydroxyingenol in which the hydroxy groups at positions 3, 13 and 20 are esterified by 2,3-dimethylbutyric acid, lauric acid and palmitic acid. Isolated from the roots of Euphorbia kansui, it exhibits anti-cancerous activity.


(+)-isodihydrocarveol

The (1S,2S,4R)-stereoisomer of dihydrocarveol.


tetraterpenoid

Any terpenoid derived from a tetraterpene. The term includes compounds in which the C40 skeleton of the parent tetraterpene has been rearranged or modified by the removal of one or more skeletal atoms (generally methyl groups).


(-)-kolavenyl diphosphate

A diterpenyl phosphate that is the O-diphospho derivative of (-)-kolavenol


A dolichyl diphosphooligosaccharide in which the oligosaccharide moiety is the Man3GlcNAc2 branched pentasaccharide alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc.


ginsenoside

Triterpenoid saponins with a dammarane-like skeleton originally isolated from ginseng (Panax) species. Use of the term has been extended to include semi-synthetic derivatives.


germacrane sesquiterpenoid

Any sesquiterpenoid having a germacrane skeleton.


(-)-neoisodihydrocarveol

A dihydrocarveol with a (1R,2S,4S)-configuration.


A sesquiterpenoid consisting of octahydro-1H-cyclopenta[1,3]cyclopropa[1,2]benzen-3-ol carrying two additional methyl substituents at positions 3 and 7 as well as an isopropyl substituent at position 4 (the 3S,3aR,3bR,4S,7S,7aR diastereomer).


The (+)-enantiomer of alpha-pinene.


hederagenin 3-O-arabinoside

A triterpenoid saponin that is hederagenin attached to an alpha-L-arabinopyranosyl residue at position 3 via a glycosidic linkage.


lancifodilactone F

A tetracyclic triterpenoid that is a rearranged pentanortriterpenoid derived from cycloartane. Isolated from the leaves and stem of Schisandra lancifolia, it exhibits anti-HIV activity.


A tricyclic sesquiterpenoid obtained by formal hydration across the endocyclic double bond of (-)-alpha-gurjunene


(+)-helminthogermacrene

The (+)-isomer of helminthogermacrene.


crassolide

A cembrane diterpenoid isolated from Lobophytum michaelae and has been shown to exhibit cytotoxic activity.


(Z,Z,Z)-geranylgeraniol

A geranylgeraniol in which all double bonds have Z- (cis-) geometry.


INFLEXIN

An ent-kaurane diterpenoid that is ent-kaur-16-ene substituted by an alpha-hydroxy group at position 1, beta-acetoxy groups at positions 3 and 6a and oxo groups at positions 11 and 15. Isolated from Isodon excisus and Rabdosia inflexa,it acts as an aromatase inhibitor.


A sesquiterpenoid that is (S)-beta-macrocarpene in which a hydrogen of the methyl group that is attached to a double bond has been replaced by a hydroxy group. The first step in the biosynthesis of the sesquiterpene phytoalexin zealexin A1 from (S)-beta-macrocarpene in maize.


A dolichyl diphosphooligosaccharide in which the oligosaccharide moiety is the Man2GlcNAc2 linear tetrasaccharide alpha-D-Man-(1->3)-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc.


gibberellin A20 methyl ester

A gibberellin ester that is the methyl ester of gibberellin A20.


A limonoid that is 17-epiazadiradione substituted by a hydroxy group at position 17. Isolated from Azadirachta indica, it exhibits antineoplastic activity.


A diastereomer of protopanaxadiol in which the 20-hydroxy substituent has been introduced at the pro-R position.


A diterpenyl phosphate that is the O-diphospho derivative of (5S,9S,10S,13E)-labda-7,13-dien-15-ol.


T-MUUROLOL

A cadinane sesquiterpenoid that consists of 4-isopropyl-1,6-dimethyl-1,2,3,4,4a,7,8,8a-octahydronaphthalene having a hydroxy substituent at position 1 and (1S,4S,4aR,8aS)-configuration.


An eremorphilane sesquiterpenoid that is (+)-5-epi-aristolochene in which the pro-R hydrogen at position 2 has been replaced by a hydroxy group.


A tridecaprenyl diphosphate having two (E)- and ten (Z)-double bonds.


all-trans-retinyl octanoate

An all-trans-retinyl ester obtained by formal condensation of the carboxy group of octanoic acid with the hydroxy group of all-trans-retinol.


A tetracyclic triterpenoid that is dammarenediol-II where the hydrogen of the hydroxy group at position 20 is replaced by a beta-D-glucoside.


BERKELEYONE C

A meroterpenoid found in Penicillium rubrum and has been shown to exhibit inhibitory activity against caspase-1.


A limonene monoterpenoid that consists of cyclohexanone bearing hydroxy and methyl substituents at position 2 as well as an isopropenyl substituent at position 5.


BERKELEYTRIONE

A  meroterpenoid found in Penicillium rubrum and has been shown to exhibit inhibitory activity against caspase-1.


(-)-delta-cadinene

A member of the cadinene family of sesquiterpenes in which the double bonds are located at the 4-4a and 7-8 positions, and in which the isopropyl group at position 1 is cis to the hydrogen at the adjacent bridgehead carbon (the 1R,8aS-enantiomer).


anisotanol C

A norsesquiterpenoid with formula C14H22O3. It is isolated from Anisodus tanguticus and displays antiangiogenic activity by inhibiting the viability, migration, and tube formation in HUVECs.


AJUGAMARIN A2 CHLOROHYDRIN

A diterpene lactone isolated from the whole plants of Ajuga ciliata.


A  scalarane sesterterpenoid isolated from the sponge, Hyattella species.


gibberellin A1 methyl ester

A gibberellin ester that is the methyl ester of gibberellin A1.


A sesquiterpene that is 1,2,3,4,4a,5,6,7-octahydronaphthalene substituted by methyl groups at positions 4 and 4a and a prop-1-en-2-yl group at position 6 (the 4R,4aR,6R-stereoisomer).


A polyprenyl phospho oligosaccharide that is a disaccharide consisting of two glucose residues linked via a diphospho group to undecaprenol.


bisabolane

A cycloalkane that is cyclohexane substituted by a methyl group at position 1 and by a 6-methylheptan-2-yl at position 4. Its skeleton structure is found in many sesquiterpenes and sesquiterpenoids.


globostellatic acid C

A tricyclic triterpenoid of the isomalabaricane group.


An abietane diterpenoid that is 5-dehydrohorminone in which the hydroxy group at position 12 is replaced by a methoxy group. Isolated from the roots of Salvia multicaulis, it exhibits antitubercular activity.


9-cis-retinyl hexadecanoate

A retinyl palmitate obtained by formal condensation of the carboxy group of hexadecanoic acid with the hydroxy group of 9-cis-retinol.


all-trans-undecaprenyl diphosphate

The all-trans-isomer of undecaprenyl diphosphate.


LYCHNOSTATIN 1

A germacranolide isolated from Lychnophora antillana and has been shown to exhibit antineoplastic activity.


A (6E)-nerolidol in which the hydroxy group at positon 3 adopts an R-configuration. It is a fertility-related volatile compound secreted by the queens of higher termites from the subfamily Syntermitinae.


A labdane diterpenoid in which the labdane skeleton has double bonds at C-7 and C-13 (the latter with E-stereochemistry) and carries a hydroxy group at the terminal C-15 atom.


A polyprenyl phospho oligosaccharide that consists of a N-acetyl-alpha-D-galactosaminyl residue linked via a diphospho group to ditrans,polycis-undecaprenol.


A polyprenyl phospho oligosaccharide that is a tetrasaccharide consisting of one glucuronic acid, one mannose and two glucose residues linked via a diphospho group to undecaprenol.


An oxabicycloalkane that is 1-methyl-4-(propan-2-yl)-7-oxabicyclo[2.2.1]heptan-2-ol in which the hydroxy group is substituted by a (2-bromo-6-fluorophenyl)methoxy group.


A tetracyclic diterpenoid with formula C20H24O7, originally isolated from the roots and leaves of Tripterygium wilfordii.


An undecaprenyl phosphate having three (E)- and seven (Z)-double bonds.


sesquiterpene lactone

Any member of a diverse class of complex, multicyclic phytochemicals showing a variety of skeleton arrangements and bioactivities, and having in common a sesquiterpenoid structure including a lactone ring.


rebaudioside D

A rebaudioside that is rebaudioside A in which the hydroxy group at position 2 of the beta-D-glucosyl ester moiety has been converted to the corresponding beta-D-glucoside. Found in minute quantities in the leaves of Stevia rebaudiana.


A  triterpenoid saponin of the class of cucurbitane glycosides isolated from the roots of  Machilus yaoshansis.


sinularolide C

A cembrane diterpenoid that is an epimer of sinularolide B at C-3. Isolated from Sinularia gibberosa and has been found to exhibit antineoplastic activity.


penichrysol

A diterpenoid that is produced by the fungal chimeric terpene synthases, PTTS087 and PTTS136.


A pentacyclic triterpenod that is 9beta,19-cyclolanost-24-ene which is substituted by hydroxy groups at the 3beta and 28 positions.


(-)-cis-carveol

The (1R,5R)-stereoisomer of carveol.


cadinene

Any sesquiterpene having a cadinane skeleton containing one or more C=C bonds.


(-)-beta-selinene

The (4aS,7S,8aR)-stereoisomer of beta-selinene.


dodecaprenyl diphosphate

A polyprenol diphosphate compound having twelve prenyl units with undefined stereochemistry about the double bonds.


A tetracyclic triterpenoid that is 29-nordammara-1,17(20)-diene substituted by acetoxy groups at positions 6 and 16, a carboxy group at position 21, a hydroxy group at position 25 and oxo groups at positions 3 and 7 respectively. It is isolated from the marine-derived fungal strain  Aspergillus sydowii PFW1-13 and exhibits antibacterial activity.


A eudesmane sesquiterpenoid in which the eudesmane skeleton carries hydroxy substituents at position 1, 6 and 7 and a double bond between C-4 and C-14. It has been isolated from the aerial parts of Tephrosia candida.


rebaudioside

Any of the steviol glycosides found in the leaves of the stevia plant, Stevia rebaudiana. They are typically more than 100 times sweeter than sucrose.


CARDIVIN A

A  germacranolide isolated from the aerial parts of Carpesium divaricatum. It exhibits cytotoxicity against the human tumor cells, A-549 (nonsmall cell lung), SK-OV-3 (ovary), SK-MEL-2 (skin), XF-498 (central nervous system) and HCT-15 (colon).


octadecaprenyl diphosphate

A polyprenol diphosphate compound having eighteen prenyl units with undefined stereochemistry about the double bonds.


manool

A labdane diterpenoid in which the labdane skeleton has double bonds at positions 8(17) and 14 and carries an R-hydroxy group at position 13.


LAMESTICUMIN E

A triterpenoid of the class of onoceranoid-type terpenoids isolated from the twigs of Lansium domesticum.


hederagenin 28-O-beta-D-glucopyranoside

A triterpenoid saponin that is the carboxylic ester obtained by the formal condensation of the carboxy group of  hederagenin with beta-D-glucopyranose.  It has been isolated from Juglans sinensis.


citranaxanthin

An apo carotenoid compound arising from oxidative degradation of the beta,beta-carotene skeleton at the 1'- and 6'-positions.


glycyrrhetic acid 3-O-glucuronide

A triterpenoid saponin that is the 3-O-beta-glucuronide of glycyrrhetic acid. It is a metabolite of glycyrrhizin contained in licorice and potentially a causative agent in the pathogenesis of pseudoaldosteronism.


A monoterpene glycoside that is albiflorin carrying a galloyl substituent at position 6. Isolated from the roots of Paeonia lactiflora.


GERANYLGERANIOL

A geranylgeraniol in which all four double bonds have E- (trans-) geometry.


9-hydroxy hedychenone

A labdane diterpenoid that is 15,16-epoxy-7,11,13(16)14-labdatetraen-6-one substituted by a hydroxy group at position 9. Isolated from the rhizomes of Hedychium spicatum, it exhibits cytotoxicity against the Colo-205 (Colo-cancer), A-431 (skin cancer), MCF-7 (breast cancer), A-549 (lung cancer) and Chinese hamster ovary cells (CHO).


A polyprenyl phospho oligosaccharide that consists of an alpha-D-Gal-(1->3)-alpha-D-GlcNAc moiety linked via a diphospho group to ditrans,octacis-undecaprenol.


BISABOLONE

A beta-bisabolene which has (1S)-configuration.


sinularolide B

A cembrane diterpenoid isolated from Sinularia gibberosa and has been found to exhibit antineoplastic activity.


A triterpenoid saponin that is olean-12-ene attached to hydroxy groups at positions 3 and 23, oxo groups at positions 1 and 28 and a beta-D-glucopyranosyloxy group at position 28. It has been isolated from the leaves and twigs of Juglans sinensis.


CLETHROIDOSIDE F

A triterpenoid saponin that is 3,16-dihydroxy-13,28-epoxyoleanane-21,22-diyl diacetate attached to a tetrasaccharide residue at position 3 via a glycosidic linkage. Isolated from the aerial parts of Lysimachia clethroides, it exhibits antineoplastic activity.


SCUTEBARBATINE F

A  diterpene alkaloid of group of neo-clerodanes isolated from the whole plants of Scutellaria barbata and has been shown to exhibit neoplastic activity.


A phorbol ester that consists of 12-deoxyphorbol esterified at position 13 by deca-3,5-dienoic acid (the 3E,5E stereoisomer). It is obtained from the leaves and stems of Excoecaria agallocha and exhibits anti-HIV activity.


DIPSACUSSAPONIN A

A triterpenoid saponin that is the disaccharide derivative of hederagenin. It has been isolated from the stem bark of Kalopanax pictus.


bacterioruberin

A C50 carotenoid that is a red-coloured pigment found in several Halobacterium and Haloarcula species.


GINSENOSIDE RF

A ginsenoside found in Panax ginseng and Panax japonicus var. major that is dammarane which is substituted by hydroxy groups at the 3beta, 6alpha, 12beta and 20 pro-S positions, in which the hydroxy group at position 6 has been converted to the corresponding beta-D-glucopyranosyl-(1->2)-beta-D-glucopyranoside, and in which a double bond has been introduced at the 24-25 position.


germacrene C

A sesquiterpenoid derived from germacrane by dehydrogenation at the 1,2- 3,4- and 7,8-positions.


OPHIOBOLIN C

A sesterterpenoid that is ophiobolane with a hydroxy group at position 3, oxo group at positions 5, formyl group at position 7, and double bonds at positions 7-8 and 19-20.


SCHISANWILSONENE A

A sesquiterpenoid isolated from Schisandra wilsoniana and has been shown to exhibit anti-HBV activity.


cabraleahydroxylactone acetate

A tetracyclic triterpenoid isolated from Aglaia abbreviata.


ANIASATIN

A sesquiterpene lactone with formula C15H20O8. It is a neurotoxic natural product found in plants of the family Illiciaceae.


azadiradionolide

A tetracyclic triterpenoid that is 4,4,8-trimethylandrosta-1,14-diene substituted by a oxo groups at positions 3 and 16, an acetoxy group at position 7 and a 2-oxo-2,5-dihydrofuran-3-yl group at position 17. It has been isolated from Azadirachta indica.


cucurbitacin B

A cucurbitacin in which a lanostane skeleton is multi-substituted with hydroxy, methyl and oxo substituents, with unsaturation at positions 5 and 23; a hydroxy function at C-25 is acetylated.


A dolichyl diphosphooligosaccharide in which the oligosaccharide moiety is the Man6GlcNAc2 branched octasaccharide alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc.


A carbobicyclic compound that is decahydronaphthalene substituted at positions 2, 4a, 8 and 8a by 2-hydroxypropan-2-yl, methyl, methyl and hydroxy groups, respectively. The (3R,4aS,5S,8aS) stereoisomer.


delta-cadinene

A member of the cadinene family of sesquiterpenes in which the double bonds are located at the 4-4a and 7-8 positions, and in which the isopropyl group at position 1 is cis to the hydrogen at the adjacent bridgehead carbon (position 8a).


sesquisabinene A

A sesquiterpene that consists of (1R,5R)-2-methylidenebicyclo[3.1.0]hexane having a (2R)-6-methylhept-5-en-2-yl group at position 5.


polyprenol phosphate

A prenol phosphate resulting from the formal condensation of the terminal allylic hydroxy group of a polyprenol with 1 mol eq. of phosphoric acid.


A diterpenoid that is 15,17-epoxypodocarpan-15-one substituted by a hydroxy group at position 13, methyl groups at positions 8 and 13 and a (5-methoxy-3,6-dioxocyclohexa-1,4-dien-1-yl)methyl group at position 14 (the 13alpha,14beta stereoisomer). Isolated from the marine sponge Petrosia corticata, it exhibits  antineoplastic activity.


A phorbol ester that consists of 16-hydroxyphorbol bearing O-hexadecanoyl (palmitoyl) and O-decanoyl substituents at position 12 and 13 respectively.


PAXILLINE

An indole diterpene alkaloid with formula C27H33NO4 isolated from Penicillium paxilli. It is a potent inhibitor of large conductance Ca2(+)- and voltage-activated K(+) (BK)-type channels.


michaolide C

A cembrane diterpenoid with cytotoxic activity isolated from the soft coral Lobophytum michaelae.


carotenoid psi-end derivative

Any carotenoid derivative with a psi-end group.


all-trans-4-oxo-18-hydroxyretinoic acid

A retinoid that consists of all-trans-retinoic acid carrying an oxo substituent at position 4 and a hydroxy substituent at position 18.


(+)-copalol

A labdane diterpenoid in which the labdane skeleton has double bonds at positions 8(17) and 13 (the latter with E-stereochemistry) and carries a hydroxy group at the terminal C-15 position.


koraiol

A carbotricyclic compound that is tricyclo[7.2.0.0(2,5)]undecane which is substituted by a hydroxy group at position 6 and by methyl groups at positions 2, 6, 10 and 10 (the 1S,2R,5S,6S,9S-diastereoisomer). It is a sesquiterpenoid isolated from Pinus koraiensis.


GLUTINOL

A pentacyclic triterpenoid that is picene which has been fully hydrogenated except for a double bond between the 4a and 5 positions and is substituted by methyl groups at the 4, 4, 6bbeta, 8abeta, 11, 11, 12balpha and 14bbeta positions, and by a hydroxy group at the 3beta position.


cis-isogeraniol

An isogeraniol that has (Z)-configuration.


neoline

A diterpene alkaloid with formula C24H39NO6 that is isolated from several Aconitum species.


picrotin

An organic heteropentacyclic compound that is picrotoxinin in which the olefinic double bond has undergone addition of water to give the corresponding tertiary alcohol. It is the less toxic component of picrotoxin, lacking GABA activity.


polyprenol

Any member of the class of  prenols possessing the general formula H-[CH2C(Me)=CHCH2]nOH in which the carbon skeleton is composed of more than one isoprene units.


AJUGALIDE B

A diterpene lactone isolated from the whole plants of Ajuga ciliata.


rebaudioside E

A rebaudioside that is stevioside in which the hydroxy group at position 2 of the glucosyl ester moiety has been converted into the corresponding beta-D-glucoside.


AGLAIABBREVIATIN E

A tetracyclic triterpenoid (dammarane type) isolated from the stems of Aglaia abbreviata.


A sesquiterpenoid that is cyclodeca-2,7-diene substituted by methyl, hydroxy, isoproyl, and methyl groups at positions 1, 1, 4S and 7, respectively.


plaunotol

A diterpenoid that is geranylgeraniol carrying an additional hydroxy substituent at position 18.


A carotenoid ether that is spirilloxanthin substituted at position 2 by a hydroxy group.


AGLAIABBREVIATIN C

A tetracyclic triterpenoid isolated from the stems of Aglaia abbreviata.


A tricyclic hydrocarbon and sesquiterpene that is octahydro-1H-3a,6-methanoazulene which is substituted by a methylidene group at position 7 and by methyl groups at positions 3, 8, and 8.


heptadecaprenyl diphosphate

A polyprenol diphosphate compound having seventeen prenyl units with undefined stereochemistry about the double bonds.


anagalligenin A

A hexacyclic triterpenoid that is an oleanane substituted by an epoxy group between positions 13 and 28 and by hydroxy groups at positions 3, 16, 22 and 28 respectively (the 3beta,16alpha,22alpha stereoisomer). It is isolated from the whole plant of Anagallis arvensis.


alpha-cryptoxanthin

A carotenol, the structure of which is (6'R)-beta,epsilon-carotene hydroxy-substituted at C-3' with R-stereochemistry.


muqubilone

A sesterterpenoid isolated from Red Sea sponge Diacarnus erythraeanus and has been shown to exhibit anti-HSV-1 activity.


solavetivol

A spiro compound that is spiro[4.5]dec-6-ene which is substituted at positions 2, 6, 8, and 10 by isopropenyl, methyl, hydroxy, and methyl groups, respectively (the (2R,5S,8S,10R)-diastereoisomer).


A polyprenyl phospho oligosaccharide where beta-D-ManNAcA-(1->4)-D-GlcNAc comprises the oligosaccharide component and is linked via a diphosphate to a polyprenyl chain consisting of eleven prenyl units.


triterpenoid

Any terpenoid derived from a triterpene. The term includes compounds in which the C30 skeleton of the parent triterpene has been rearranged or modified by the removal of one or more skeletal atoms (generally methyl groups).


cornusalterin C

A tirucallane triterpenoid that is (13alpha,14beta,17alpha,20S,23E)-lanosta-23-ene substituted by beta-hydroxy group at position 3 and a methoxy group at position 25. It has been isolated from the stem and stem barks of Cornus walteri.


cyclic monoterpene ketone

A cyclic terpene ketone in which the terpene specified is monoterpene.


KLYMOLLIN A

An eunicellin diterpenoid isolated from the soft coral Klyxum molle.


An oligosaccharide phosphate that is beta-D-Man-(1->4)-beta-D-GlcA-(1->2)-alpha-D-Man-(1->3)-beta-D-Glc-(1->4)-alpha-D-Glc-1-diphospho-ditrans,polycis-undecaprenol in which the terminal mannosyl group has been converted to its 4,6-O-1-carboxyethylidene derivative.


A carotenol obtained by formal hydration of a double bond at position 1' of demethylspheroidene.


3-acetyl-7-tigloylvilasinin lactone

A limonoid found in Azadirachta indica.


A diterpenoid that is ent-cassa-12,15-diene in which the hydrogens at positions 2beta and 3beta have been replaced by hydroxy groups.


avermitilol

A carbotricyclic compound that consists of decahydro-1H-1H-cyclopropa[a]naphthalene bearing four methyl substituents at position 1, 1, 3a and 7 as well as a hydroxy substituent at position 4 (the (1aR,3aS,4S,7R,7aS,7bR)-diastereomer).


quassinoid

Members of the class of triterpenoid, mostly isolated as bitter principles of the Simaroubaceae family. They are chemically regarded as degraded triterpenes and can be categorized into groups with C18, C19, C20, C22 and C25 skeletons.


A diterpenoid that is podocarpa-5,8,11,13-tetraen-7-one substituted by hydroxy groups at positions 3 and 12 and a methyl group at position 13 (the 3beta stereoisomer). Isolated from Securinega suffruticosa, it exhibits antineoplastic activity.


A germacrane sesquiterpenoid that is germacra-1(10),4-diene carrying an additional hydroxy substituent at position 11.


smaditerpenic acid C

A diterpenoid isolated from the leaves of Smallanthus sonchifolius.


(+)-alpha-santalene

A sesquiterpene consisting of a tricyclo[2.2.1.0(2,6)]heptane skeleton substituted by methyl groups at positions 1 and 7 and by a 4-methylpent-3-en-1-yl group at position 7 (the 1S,2R,4S,6R,7R diastereoisomer).


glycan G00008

A dolichyl diphosphooligosaccharide compound consisting of a branched tetradecasaccharide attached to the dolichyl chain via a diphosphate linkage.


linalool

A monoterpenoid that is octa-1,6-diene substituted by methyl groups at positions 3 and 7 and a hydroxy group at position 3. It has been isolated from plants like Ocimum canum.


conidiogenol

A diterpenoid with formula C20H34O2. It is isolated from Penicillium cyclopium and exhibits potent conidiation inducing activity.


A polyprenyl glycosyl phosphate consisting of N,N'-diacetyl-alpha-D-bacillosamine linked via a diphospho group to tritrans,heptacis-undecaprenol.


(+)-phytocassane E

A phytocassane that is (+)-phytocassane C in which the hydroxy group at position 3 has been oxidised to the give corresponding ketone.


NEROLIDOL

A nerolidol in which the double bond at position 6 adopts a trans-configuration.


flavuxanthin

A C50 carotenoid that is an intermediate in the biosyntheses of decaprenoxanthin by Corynebacterium glutamicum and gamma-cyclic sarcinaxanthin by Micrococcus luteus.


A limonoid that is  salannin in which the furanyl group at position 17 is replaced by an oxo group. Isolated from Azadirachta indica, it exhibits anti-inflammatory activity.


tetradecaprenyl diphosphate

A polyprenol diphosphate compound having fourteen prenyl units with undefined stereochemistry about the double bonds.


salvileucalin B

A diterpenoid with a rearranged neo-clerodane skeleton isolated from Salvia leucantha and has been shown exhibit antineoplastic activity.


AJUGANIPPONIN A

A  diterpene lactone isolated from the whole plants of Ajuga ciliata.


isoiguesterin

A pentacyclic triterpenoid that is a bisnortriterpene isolated from Salacia madagascariensis and exhibits antileishmanial and antileukemic activities.


11-cis-retinyl tetradecanoate

A retinyl ester obtained by formal condensation of the carboxy group of tetradecanoic acid with the hydroxy group of 11-cis-retinol.


colleterpenol

A triterpenoid produced by Colletotrichum gloeosporioides colleterpenol synthase from all-trans-hexaprenyl diphosphate.


tridecaprenyl diphosphate

A polyprenol diphosphate compound having thirteen prenyl units with undefined stereochemistry about the double bonds.


trifloroside

A secoiridoid glycoside that is (4aS,5R,6R)-6-hydroxy-5-vinyl-4,4a,5,6-tetrahydro-1H,3H-pyrano[3,4-c]pyran-1-one in which the hydroxy group has been converted to the corresponding 2,3,6-tri-O-acetyl-beta-D-glucoside, the 4-hydroxy group of which has been esterified by formal condensation with the carboxy group of 2,3-dihydroxybenzoic acid 3-beta-D-glucoside. It is a component of Gentiana scabra root extract, which is used as an internal remedy in traditional Korean medicine for the treatment of diabetes mellitus.


tatridin A

A germacrane sesquiterpenoid in which the 10-membered ring contains one E- and one Z- double bond and is fused to a 3-methylenedihydrofuran-2(3H)-one moiety. It has been isolated from Artemesia arbuscala, Anthemis altissima and Tanacetum vulgare.


A terpene lactone that is obtained from Codinea simplex and acts as an inhibitor of glycerophosphoinositol biosynthesis.


thujopsene

A carbotricyclic compound that is cis-1,1a,4,4a,5,6,7,8-octahydrocyclopropa[d]naphthalene which is substituted by methyl groups at the 2, 4a, 8 and 8 positions.


A sesquiterpene that consists of (1S,5R)-2-methylbicyclo[3.1.0]hex-2-ene having a (2R)-6-methylhept-5-en-2-yl group attached at position 5.


michaolide J

A cembrane diterpenoid with cytotoxic activity isolated from the soft coral Lobophytum michaelae.


viridiflorol

A carbotricyclic compound that is (1aS,4aR,7aR,7bR)-decahydro-1H-cyclopropa[e]azulene carrying four methyl substituents at positions 1, 1, 4 and 7 as well as a hydroxy substituent at position 4. It is a sesquiterpenoid isolated from several plant species and is a strong feeding deterrent for the melaleuca weevil that retards larval development.


A carbobicylic compound that is (8aS)-1,2,3,3a,4,5,8,8a-octahydroazulene substituted by a propan-2-ylidene, methyl and methyl groups at positions 1, 3aR and 6, respectively.


A triterpenoid saponin with rubiarbonol A as the aglycone. It has been isolated from the roots of Rubia yunnanensis.


A dodecaprenyl diphosphate having two (E)- and nine (Z)-double bonds.


A steroid acid that is 4beta,14-dimethyl-5alpha,9beta-9,19-cyclocholest-24-en-3beta-ol in which the 4alpha hydrogen has been replaced by a carboxy group.


areptin A

A diterpenoid isolated from the aerial parts of Ajuga reptans.


A pentacyclic triterpenoid that is lupane in which the hydrogens at the 3beta and 20 positions are substituted by hydroxy groups.


alatolide

A germacrane sesquiterpenoid laactone obtained by formal condensation of the carboxy group of isobutyric acid with the secondary hydroxy group of trihydroxygermaeranolide.


A  triterpenoid saponin that is cucurbitacin I attached to a beta-D-glucopyranosyl residue at position 2 via a glycosidic linkage. It has been isolated from  Machilus yaoshansis.


CAESALPININ C

A tetracyclic diterpenoid isolated from the seed kernels of Caesalpinia crista that has been found to exhibit antimalarial activity.


(R)-(+)-alpha-terpineol

The (4R)-stereoiosmer of alpha-terpineol.


23,24-DIHYDROCUCURBITACIN B

A 23,24-dihydrocucurbitacin in which a lanostane skeleton is multi-substituted with hydroxy, methyl and oxo substituents, with unsaturation at position 5; a hydroxy function at C-25 is acetylated.


LOBOHEDLEOLIDE

A cembrane diterpenoid isolated from Lobophytum hedleyi and Lobophytum. It exhibits anti-HIV-1 activity.


A phorbol ester that is 12-deoxyphorbol in which the hydroxy groups at positions 13 and 20 have been converted to their  respective 2-methylbutanoate and acetate esters.


A member of the class of carotenone that is echinenone carrying an additional hydroxy substituent at position 3'. Found in cyanobacteria.


A dehydrovomifoliol that has S-configuration at the chiral centre.


CAESALPININ D

A diterpenoid lactone isolated from the seed kernels of Caesalpinia crista that has been found to exhibit antimalarial activity.


bicyclosesquiphellandrene

An octahydronaphthalene that is 1,2,3,4,4a,5,6,7-octahydronaphthalene substituted by isopropyl, methyl, and methylidene groups at positions 1, 4 and 7, respectively (the (1S,4R,4aR)-stereoisomer).


pneumocysterol

A tetracyclic triterpenoid that is (24Z)-24-ethylidenelanost-8-ene substituted by a hydroxy group at the 3beta position.


A diterpenoid that is 11-oxo-ent-cassa-12,15-diene carrying two additional alpha-hydroxy substituents at positions 2 and 3.


poly-cis-polyprenyl diphosphate

Any polyprenol diphosphate in which all of the tetrasubstituted C=C double bonds have cis configuration.


triptobenzene A

An abietane diterpenoid with formula C20H28O3, originally isolated from Tripterygium wilfordii.


tinyatoxin

A heteropentacyclic compound found in Euphorbia poissonii with molecular formula C36H38O8. It is an agonist of the transient receptor potential cation channel subfamily V member 1 (TrpV1).


isotalatizidine

A diterpene alkaloid that is aconitane bearing hydroxy groups at the 1alpha, 8, and 14alpha positions and substituted at on the nitrogen and at positions 4 and 16beta by ethyl, methoxymethyl, and methoxy groups, respectively.


farnesene

A sesquiterpene that is any of the four possible isomers of 3,7,11-trimethyl-1,3,6,10-dodecatetraene (alpha-farnesene) or of the two possible isomers of 7,11-dimethyl-3-methylene-1,6,10-dodecatriene.


A tricyclic sesquiterpene that is 2,4,4a,5,6,7,7a,7b-octahydro-1H-cyclobuta[e]indene bearing four methyl substituents at positions 3, 6, 6 and 7b.


(+)-alpha-gurjunene

A tricyclic sesquiterpene that is 1a,2,3,4,4a,5,6,7b-octahydro-1H-cyclopropa[e]azulene carrying four methyl substituents at positions 1, 1, 4 and 7.


A diacetylchitobiosyldiphosphodolichol in which a trimannosyl group consisting of one beta-D-mannosyl and two alpha-D-mannosyl residues is attached at an unspecified position to the diacetylchitobiosyldiphosphodolichol moiety.


tetracyclic diterpenoid

A diterpenoid with a tetracyclic skeleton.


bullatantriol

A sesqiterpenoid that is octahydro-1H-indene which is substituted by a 2-hydroxy-2-methylpropyl group at position 1, methyl groups at positions 3a and 7, and hydroxy groups at positions 4 and 7 (the 1R,3aR,4R,7S,7aR stereoisomer). It has been isolated from various Homalomena species.


globostellatic acid D

A tricyclic triterpenoid of the isomalabaricane group.


sordaricin

A tetracyclic diterpenoid that is produced by several fungi including Sordaria araneosa.


all-cis-polyprenol phosphate

A polyprenol phosphate in which all the C=C double bonds have cis (Z) configuration.


forskoditerpenoside D

A diterpene glycoside that is labd-14-en-11-one substituted by beta-acetoxy groups at positions 6 and 7, an epoxy group between positions 8 and 13 and a beta-D-glucopyranosyloxy group at position 1 (the 1alpha stereoisomer). Isolated from the whole plant of Coleus forskohlii, it shows relaxative effects on isolated guinea pig tracheal spirals in vitro.


BERKELEYONE A

A  meroterpenoid found in Penicillium rubrum and has been shown to exhibit inhibitory activity against caspase-1.


A dolichyl diphosphooligosaccharide in which the oligosaccharide moiety is the Man9Glc2GlcNAc2 branched tridecasaccharide alpha-D-Glc-(1->3)-alpha-D-Glc-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc.


farnesane

A sesquiterpene that is dodecane substituted by methyl groups at positions 2, 6 and 10.


terpineol

A family of monoterpenols that have a p-menthane skeleton containing one double bond and bearing a single hydroxy substituent.


GINSENOSIDE RH2

A ginsenoside found in Panax species that is dammarane which is substituted by hydroxy groups at the 3beta, 12beta and 20 pro-S positions, in which the hydroxy group at position 3 has been converted to the corresponding beta-D-glucopyranoside, and in which a double bond has been introduced at the 24-25 position.


A dolichyl diphosphooligosaccharide in which the oligosaccharide moiety is the Man1GlcNAc2 linear trisaccharide beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc.


A cholestanoid that is 5alpha-cholesta-8-en-3beta-ol bearing two additional methyl substituents at position 4.


dihydrofukinolide

A sesquiterpene lactone that is (3R,3a'R)-decahydrospiro[furan-3,2'-indene] carrying an oxo, methylene, acetoxy, [(2S)-2-methylbutanoyl]oxy, methyl and methyl groups at positions 2, 4, 3', 4', 7' and 7a', respectively.


A sesquiterpenoid consisting of octahydro-1H-cyclopenta[1,3]cyclopropa[1,2]benzen-3-ol carrying two additional methyl substituents at positions 3 and 7 as well as an isopropyl substituent at position 4 (the 3S,3aS,3bS,4R,7S,7aS diastereomer).


A polyprenyl phospho oligosaccharide where N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-D-glucosaminyl comprises the oligosaccharide component and the polyprenyl chain consists of eleven prenyl units.


A cyclic carotene that is beta-carotene which the double bond between positions 7 and 8 has been hydrogenated.


hokbusine A

A diterpene alkaloid with formula C32H45NO10, originally isolated from Aconitum jaluense.


paeonilactinone

A cyclic monoterpene ketone that is bicyclo[3.1.1]heptan-2-one which is substituted at positions 4, 6, and 6 by hydroxymethyl, methyl, and methyl groups (the 1R,4S,5R stereoisomer). It has been found in Japanese Paeoniae Radix, which has been used in various Chinese medicinal preparations as an anodyne, sedative, antispasmodic, and astringent.


(Z,S)-cinerolone

A beta-hydroxy ketone that is cyclopent-2-en-1-one which is substituted at positions 2, 3, and 4 by (2Z)-but-2-en-1-yl, methyl, and hydroxy groups, respectively (the 2S enantiomer).


monoterpene ketone

A terpene ketone derived from a monoterpene.


sesterterpenoid

Any terpenoid derived from a sesterterpene. The term includes compounds in which the C25 skeleton of the parent sesterterpene has been rearranged or modified by the removal of one or more skeletal atoms (generally methyl groups). Sometimes sesterterpenoids are erroneously referred to as sesterpenoids.


An epoxycarotenol that beta-cryptoxanthin in which the 5,6-double bond has been epoxidised.


(-)-endo-alpha-bergamotene

A cis-alpha-bergamotene that has (S,S,S)-configuration.


A phorbol ester that is phorbol in which the hydroxy groups at the cyclopropane ring juction (position 13) and the adjacent carbon (position 12) have been converted to the corresponding decanoate esters. A Trpv4-specific ligand.


all-trans-3,4-didehydroretinoic acid

A retinoid obtained by 3,4-desaturation of beta-ionone ring of all-trans-retinoic acid


A sesquiterpene with a [7.2.0]-bicyclic structure comprising fused 9- and 4-membered rings, with a cis-ring junction, a methylidene group at position 9, and methyl groups at positions 3, 11, and 11.


triptohypol F

A pentacyclic diterpenoid with formula C31H52O2, originally isolated from the leaves of Tripterygium hypoglaucum.


mogroside I-A1

A mogroside that is mogrol in which the hydroxyl hydrogen at position 24 has been replaced by a beta-D-glucosyl residue.


(R,R)-chrysanthemyl diphosphate

The (R,R)-diastereoisomer of chrysanthemyl diphosphate.


A bicyclic sesquiterpene that is 1,2,6,7,8,8a-hexahydroazulene carrying an isopropyl substituent at position 5 as well as two methyl substituents at positions 5 and 8.


alpha-onocerin

A triterpenoid that is ethane in which each carbon has been substituted by a (1R,4aR,6S,8aS)-6-hydroxy-5,5,8a-trimethyl-2-methylenedecahydronaphthalen-1-yl group.


AJUGACILIATIN E

A diterpene lactone isolated from the whole plants of Ajuga ciliata.


bruceine D

A  quassinoid that is 13,20-epoxypicras-3-ene substituted by hydroxy groups at positions 1, 11, 12, 14 and 15 and oxo groups at positions 2 and 16. Isolated from the ethanol extract of the stem of Brucea mollis, it exhibits cytotoxic activity.


neotriptophenolide

A tetracyclic diterpenoid with formula C21H26O4, originally isolated from Tripterygium wilfordii and Tripterygium hypoglaucum


A sesquiterpenoid consisting of a tricyclic carbon skeleton functionalised by a tertiary hydroxy group.


A carbobicyclic compound that is 1,2,3,4,5,6-hexahydroazulene substituted by methyl groups at positions 1S and 4S and by an isoproyl group at position 7. It is a sesquiterpene synthesised by heterologous expression of a sesquiterpene cyclase from the deep-sea fungus Spiromastix sp.


terpene

A hydrocarbon of biological origin having carbon skeleton formally derived from isoprene [CH2=C(CH3)CH=CH2].


petasin

An enoate ester obtained by formal condensation of the carboxy group of angelic acid with the hydroxy group of (1R,2R,7S,8aR)-1,8a-dimethyl-6-oxo-7-(prop-1-en-2-yl)-1,2,3,4,6,7,8,8a-octahydronaphthalen-2-ol.


A carotenoid ether that is spirilloxanthin substituted at positions 2  and 2' by oxo and hydroxy groups respectively.


marianoside B

A triterpene glycoside that is lanost-8-ene substituted by a methylidene group at position 24 and a beta-D-glucopyranosyloxy group at position 3. Isolated from the whole plant of Silybum marianum, it exhibits inhibitory activity against chymotrypsin.


A sesquiterpene that is (9aS)-5,6,7,8,9,9a-hexahydro-1H-benzo[7]annulene substituted by methyl groups at positions 3, 5, 5 and 9R. It is a pheromone produced by males of several Phyllotreta species.


fusaterpenol

A diterpenoid synthesised by a monofunctional diterpene synthase from Fusarium graminearum.


A retinoid obtained by formal hydrogenation across the 7,8-double bond of all-trans-retinol


sesquithujene

A sesquiterpene that consists of (1S,5R)-2-methylbicyclo[3.1.0]hex-2-ene having a (2S)-6-methylhept-5-en-2-yl group attached at position 5.


(R,R)-chrysanthemol

A chrysanthemol in which both chiral centres have R configuration.


viridiflorene

A carbotricyclic sesquiterpene obtained from several natural sources, including Australian Tea Tree oil (Melaleuca alternifolia.)


(Z,E)-alpha-farnesene

The (Z,E)-stereoiosmer of alpha-farnesene.


sibiskoside

A monoterpene glycoside that is geraniol-5,10-olide glycosylated at position 1 by a beta-D-glucopyranosyl group. Isolated from the aerial parts of Sibiraea angustata, it exhibits anti-obesity activity.


(-)-CAMPHENE

A camphene (2,2-dimethyl-3-methylenebicyclo[2.2.1]heptane) that has S configuration at position 1 and R configuration at position 4.


A  triterpenoid saponin of the class of cucurbitane glycosides isolated from  Machilus yaoshansis.


A ent-kaurane diterpenoid that is ent-kaurane-19-oic acid substituted by hydroxy groups at positions 16 and 17 (the 16beta stereoisomer). It is isolated from Helianthus sp. and Annona squamosa and exhibits anti-HIV activity.


dihydrobisanhydrobacterioruberin

A C50 carotenoid that is an intermediate in the biosynthesis of bacterioruberin, a red-coloured pigment found in several Halobacterium and Haloarcula species.


auroxanthin

An epoxycarotenol that consists of 5,6,5',8'-tetrahydro-beta,beta-carotene-3,3'-diol having epoxy groups at the 5,8- and 5',8'-positions.


(+)-valencene

A carbobicyclic compound and sesquiterpene that is 1,2,3,4,4a,5,6,7-octahydronaphthalene which is substituted a prop-1-en-2-yl group at position 3 and by methyl groups at positions 4a and 5  (the 3R,4aS,5R- diastereoisomer).


combretanone B

A pentacyclic triterpenoid that is 9beta,19-cyclolanostane substituted by an oxo group at position 3 and hydroxy groups at positions 7, 23R*, 24S*, 25 and 28. It has been isolated from the leaves of Combretum quadrangulare.


farnesyl triphosphate

A polyprenol triphosphate where the polyprenol component is farnesol.


A carotenol that is (3'E)-3',4'-didehydro-1',2'-dihydro-beta,psi-carotene which carries a hydroxy group at position 1'.


phytocassane

Any member of a group of tricyclic diterpenoids isolated from Magneporthe grisea-infected rice leaves or Rhizoctonia solani-infected rice stems. They were initially identified as cassane diterpenoids, but were subsequently found to have the enantiomeric (ent-cassane) configuration.


demethylspheroidene

The carotenol formed by demethylation of the carotenoid ether spheroidene.


A diterpenoid that is the 11alpha-hydroxy-derivative of ent-cassa-12,15-diene.


AJUGAMARIN A2

A diterpene lactone isolated from the whole plants of Ajuga ciliata.


A dolichyl diphosphooligosaccharide intermediate involved in post-translational modification of proteins.


(+)-homalomenol B

A sesquiterpenoid that is (+)-homalomenol A in which the double bond of the 2-methylpropen-1-yl group has migrated from the 1-2 position to the 2-3 position.


GINSENOSIDE RH1

A tetracyclic triterpenoid that is (20S)-protopanaxadiol which is substituted by beta-D-glucoside at the 6alpha position.


melleolide F

A sesquiterpenoid resulting from the formal condensation of the carboxy group of o-orsellinic acid with the 2-hydroxy group of (2R,2aS,4aS,7aS,7bR)-3-(hydroxymethyl)-6,6,7b-trimethyl-1,2,4a,5,6,7,7a,7b-octahydro-2aH-cyclobuta[e]indene-2,2a-diol. It is a metabolite isolated from the fungus Armillaria mellea.


CARDIVIN C

A germacranolide isolated from the aerial parts of Carpesium divaricatum. It exhibits cytotoxicity against the human tumor cells, A-549 (nonsmall cell lung), SK-OV-3 (ovary), SK-MEL-2 (skin), XF-498 (central nervous system) and HCT-15 (colon).


A polyprenyl phospho oligosaccharide that consists of an alpha-D-GalNAc-(1->3)-alpha-D-GalNAc moiety linked via a diphospho group to ditrans,octacis-undecaprenol.


A 1(10),5-germacradien-4-ol in which the hydroxy group has R-configuration


A lathyrane diterpenoid isolated from the roots of Euphorbia micractina.


ZURETINOL

A retinol in which the double bond at position 9 has cis configuration, whilst the remaining acyclic double bonds have trans configuration.


SIMALIKALACTONE D

A quassinoid isolated from Quassia amara and Quassia africana. It has been shown to exhibit  antimalarial, cytotoxic and antiviral activities.


SOLANESOL

A nonaprenol that is hexatriaconta-2,6,10,14,18,22,26,30,34-nonaen-1-ol substituted by 9 methyl groups at positions 3, 7, 11, 15, 19, 23, 27, 31 and 35 (the all-trans0stereoisomer).


A carbotricyclic compound that is tricyclo[6.3.1.0(2,5)]dodecane which is substituted by a hydroxy group at position 1 and by methyl groups at positions 4, 4, and 8 (the  1S,2R,5S,8R-diastereoisomer).


EURYCOMANONE

A  quassinoid isolated from Eurycoma longifolia and has been shown to exhibit antineoplastic and antimalarial activties.


alpha-guaiene

A carbobicyclic compound and sesquiterpene that is 1,2,3,4,5,6,7,8-octahydroazulene which is substituted by methyl groups at positions 1 and 4 and by a (prop-1-en-2-yl group at position 7 (the 1S,4S,7R enantiomer).


A dolichyl diphosphooligosaccharide in which the oligosaccharide moiety is the Man9Glc3GlcNAc2 branched tetradecasaccharide alpha-D-Glc-(1->2)-alpha-D-Glc-(1->3)-alpha-D-Glc-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc.


A polyprenyl phospho oligosaccharide where alpha-D-FucNAc4-(1->4)-beta-D-ManNAcA-(1->4)-D-GlcNAc comprises the oligosaccharide component and is linked via a diphosphate to a polyprenyl chain consisting of eleven prenyl units.


citrifolinoside

An unusual iridoid monoterpenoid isolated from the leaves of Morinda citrifolia. It exhibits significant inhibition of UVB-induced Activator Protein-1 (AP-1) activity in cell cultures.


A scalarane sesterterpenoid  that is 12-O-deacetyl-12-epi-19-deoxy-scalarin substituted by an additional hydroxy group at position 21. It has been isolated from the sponge, Hyattella species.


A pentacyclic triterpenoid that is urs-12-ene substituted by a carboxy group at position 28, alpha-configured hydroxy groups at positions 2 and 19 and an oxo group at position 3. Isolated from the whole plants of Geum japonicum, it exhibits activity against HIV-1 protease.


sapintoxin D

A phorbol ester consisting of phorbol that is acylated at positions 12 and 13 by 2-(methylamino)benzoyl and acetyl groups respectively.


hastatoside

An iridoid monoterpenoid with formula C17H24O11 that is isolated from several plants including Verbena officinalis and exhibits a sleep-promoting effect.


ambrein

A triterpenoid alcohol that is a constituent of ambergris, an intestinal secretion of the sperm whale Physeter catodon.


staphyloxanthin

A xanthophyll that is beta-D-glucopyranose in which the hydroxy groups at positions 1 and 6 have been acylated by an all-trans-2,6,10,15,19,23-hexamethyltetracosa-2,4,6,8,10,12,14,16,18,22-decaenoyl group and a 12-methyltetradecanoyl group, respectively. Staphyloxanthin is responsible for the characteristic yellow-golden colour which gives the bacterium Staphylococcus aureus its name.


WILFOLIC ACID C

A pentacyclic triterpenoid with formula C30H48O4, originally isolated from Tripterygium doianum.


paeoniflorin sulfonate

A monoterpene glycoside with formula C23H28O14S, originally isolated from the roots of Paeonia lactiflora.


A  diterpenoid that is 13,14,15,16-tetranorlabdane substituted  by hydroxy grousp at positions 8, 12 and 18. It has been isolated from the aerial parts of Crassocephalum mannii and has been shown to exhibit COX-1 and COX-2 activity.


sativene

A sesquiterpene that is octahydro-1H-1,4-methanoindene bearing methyl, isopropyl and methylene substituents at positions 4, 7 and 8 respectively (the 1R,3aS,4R,7R,7aR-isomer).


LYSIKOKIANOSIDE 1

A triterpenoid saponin that is (3beta,16alpha)-13,28-epoxyoleanane-3,16-diol attached to a tetrasaccharide residue at position 3 via a glycosidic linkage. Isolated from aerial parts of Lysimachia clethroides, it exhibits antineoplastic activity.


cyathadiol

A tricyclic diterpenoid with formula C20H32O2.


A pentacyclic triterpenoid that is olean-12-ene substituted by an oxo substituent at position 3 and a beta-hydroxy group at position 21. Isolated from the root barks of Hippocratea excelsa, it exhibits antigiardial activity.


An N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-D-glucosaminyl undecaprenyl diphosphate in which the anomeric centre connected to the diphosphate group has alpha-configuration.


BICYCLOGERMACRENE

A sesquiterpene derived from germacrane by dehydrogenation across the C(1)-C(10) and C(4)-C(5) bonds and cyclisation across the C(8)-C(9) bond.


(+)-epicubenol

A carbobicyclic compound that is cis-decalin substituted by a propan-2-yl group at position 1, methyl groups at position 4 and 7, and a hydroxy group at position 4a, and containing a double bond between positions 7 and 8 (the 1R,4S,4aR,8aS diastereoisomer).


isogeraniol

A homoallylic alcohol that is 2,6-dimethylocta-2,5-diene in which a hydrogen of the methyl group at position 8 has been replaced by a hydroxy group.


The 5alpha,9beta,10alpha-diastereomer of copalyl diphosphate.


(-)-alpha-isocomene

A tricyclic sesquiterpene that is 1,2,3,3a,5a,6,7,8-octahydrocyclopenta[c]pentalene bearing four methyl substituents at positions 1, 3a, 4 and 5a.


A dolichyl diphosphooligosaccharide in which the oligosaccharide moiety is the Man9GlcNAc2 branched undecasaccharide alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc.


(-)-abscisic acid

The (1'R)-(-) enantiomer of abscisic acid, which does not occur naturally.


A  limonoid that is  epoxyazadiradione in which the acetyl group has been replaced by a benzoyl group. It has been isolated from Azadirachta indica.


3-O-trans-p-coumaroyl actinidic acid

A pentacyclic triterpenoid that is the cinnamate ester obtained by the formal condensation of the carboxy group of trans-4-coumaric acid with the hydroxy group at position 3 of actinidic acid (the 2alpha,3beta stereoisomer). It is isolated from the roots of Actinidia arguta and exhibits inhibitory activity towards pancreatic lipase.


prespatane

A carbotricyclic compound that is decahydrocyclobuta[1,2-a:3,4-a']dicyclopentene substituted by prop-1-en-2-yl, methyl and methyl groups at positions 1, 3a and 6, respectively (the 1S,3aS,3bR,6S,6aS,6bS-stereoisomer). It is a sesquiterpene initially isolated from the tropical marine sponge Cymbastela hooperi.


PREAUSTINOID A

A  meroterpenoid  found in Penicillium rubrum.


AJUGANIPPONIN B

A  diterpene lactone isolated from the whole plants of Ajuga ciliata.


A limonoid isolated from Azadirachta indica.


cimifoetiside B

A triterpene glycoside that consists of cimigenol attached to a beta-D-glucopyranosyl-(1->2)-beta-D-xylopyranosyl moiety at position 3 via a beta-glycosidic linkage (the 23R,24S stereoisomer). It is isolated from the aerial parts of Cimicifuga foetida and exhibits significant immunosuppressive effect.


anisotanol D

A norsesquiterpenoid with formula C14H22O3. It is isolated from Anisodus tanguticus.


beta-acoradiene

A spiro compound that is 1,8-dimethyl-4-(prop-1-en-2-yl)spiro[4.5]decane that has been dehydrogenated to introduce a double bond at position 8-9 (the 1R,4S,5R isomer).


A polyprenyl phospho polysaccharide that consists of the polysaccharide 3-O-phospho-[2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-alpha-D-Man-(1->]n-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-GlcNAc linked via a diphospho group to ditrans,octacis-undecaprenol.


phorbol 12-myristate 13-acetate

A phorbol ester that is phorbol in which the hydroxy groups at the cyclopropane ring juction (position 13) and the adjacent carbon (position 12) have been converted into the corresponding acetate and myristate esters. It is a major active constituent of the seed oil of Croton tiglium. It has been used as a tumour promoting agent for skin carcinogenesis in rodents and is associated with increased cell proliferation of malignant cells. However its function is controversial since a decrease in cell proliferation has also been observed in several cancer cell types.


sesquiterpenoid

Any terpenoid derived from a sesquiterpene. The term includes compounds in which the C15 skeleton of the parent sesquiterpene has been rearranged or modified by the removal of one or more skeletal atoms (generally methyl groups).


A carotenol obtained by formal dihydroxylation across the 15,15'-double bond of beta-carotene.


(R)-beta-himachalene

The (R)-enantiomer of beta-himachalene.


(-)-trans-pinocarveol

The (1S,3R,5S)-stereoisomer of pinocarveol.


isonordoperoxide

A sesquiterpenoid that is 1,4,5,6,7,8-hexahydro-4,7-epidioxyazulen-3(2H)-one substituted by a hydroxy group at position 8, methyl groups at positions 1 and 4 and an isopropyl group at position 7 (the (1R,4R,7S,8S stereoisomer). Isolated from Nardostachys chinensis, it exhibits antimalarial activity.


A member of the class of carotenone that is echinenone carrying two additional hydroxy substituents at position 4'.


A sesquiterpenoid that is 1,2,3,3a,4,5,8,8a-octahydroazulene substituted by hydroxy groups, isopropyl and methyl groups at positions 1, 2, 1, 3a and 6 respectively. It is isolated from the culture broth of Gliocladium virens and exhibits antifungal activity.


AJUGACUMBIN A CHLOROHYDRIN

A diterpene lactone isolated from the whole plants of Ajuga ciliata.


hydropyrenol

A tetracyclic diterpenoid, isolated from Streptomyces avermitilis host carrying the sclav_p0765 gene.


zerumboneoxide

A sesquiterpenoid that is the 2, 3-epoxy derivative of zerumbone. Isolated from  Zingiber zerumbet, it exhibits inhibitory activity against nitric oxide synthase.


luzonial A

An iridoid monoterpenoid that is hexahydro-1H-cyclopenta[c]furan substituted by hydroxy groups at positions 1 and 3a, a 3-oxopropen-2yl group at position 6 and a trans-4-coumaroyloxy moiety at position 4 (the 1S,3aS,4S,6S,6aS stereoisomer). Isolated from the leaves of Viburnum luzonicum, it exhibits antineoplastic activity.


GINSENOSIDE RC

A ginsenoside found in Panax ginseng that is dammarane which is substituted by hydroxy groups at the 3beta, 12beta and 20 pro-S positions, in which the hydroxy groups at positions 3 and 20 have been converted to the corresponding beta-D-glucopyranosyl-(1->2)-beta-D-glucopyranoside and alpha-L-arabinofuranosyl-(1->6)-beta-D-glucopyranoside respectively, and in which a double bond has been introduced at the 24-25 position.