name: NDUS3_HUMAN NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial (sprot)

description: An NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial that is encoded in the genome of human.


name: LIGO2_HUMAN Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 2 (sprot)

description: A leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 2 that is encoded in the genome of human.


name: SYMC_HUMAN Methionine--tRNA ligase, cytoplasmic (sprot)

description: A methionine--tRNA ligase, cytoplasmic that is encoded in the genome of human.


name: AP1S2_HUMAN AP-1 complex subunit sigma-2 (sprot)

description: An AP-1 complex subunit sigma-2 that is encoded in the genome of human.


atrioventricular block

category: biolink:Disease biolink:DiseaseOrPhenotypicFeature biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing

description: A heart block that is initiated in the atrioventricular node.


name: CCR8_HUMAN C-C chemokine receptor type 8 (sprot)

description: A C-C chemokine receptor type 8 that is encoded in the genome of human.


salbutamol

A member of the class of phenylethanolamines that is 4-(2-amino-1-hydroxyethyl)-2-(hydroxymethyl)phenol having a tert-butyl group attached to the nirogen atom. It acts as a beta-adrenergic agonist used in the treatment of asthma and chronic obstructive pulmonary disease (COPD).


name: SC6A3_HUMAN Sodium-dependent dopamine transporter (sprot)

description: A sodium-dependent dopamine transporter that is encoded in the genome of human.


econazole

A racemate composed of equimolar amounts of (R)- and (S)-econazole. Used (as its nitrate salt) to treat skin infections such as athlete's foot, jock itch, ringworm and other fungal skin infections.


malignant glioma

description: A grade III or grade IV glioma arising from the central nervous system. This category includes glioblastoma, anaplastic astrocytoma, anaplastic ependymoma, anaplastic oligodendroglioma, and anaplastic oligoastrocytoma.


erythroleukemia

description: An acute erythroid leukemia characterized by the presence of at least 50% erythroid precursors and at least 20% myeloblasts in the bone marrow.


optic neuritis

description: Optic neuritis is inflammation of the optic nerve, the nerve that carries the visual signal from the eye to the brain.The conditionmay cause sudden, reduced vision in the affected eye(s). While the cause of optic neuritis is unknown, it has been associated with autoimmune diseases, infections, multiple sclerosis, drug toxicity and deficiency of vitamin B-12. Vision often returns to normal within 2-3 weeks without treatment. In some cases, corticosteroids are given to speed recovery. If known, the underlying cause should be treated.


Klebsiella pneumonia

description: An pneumonia caused by infection with Klebsiella.


name: RAD50_HUMAN DNA repair protein RAD50 (sprot)

description: A DNA repair protein RAD50 that is encoded in the genome of human.


name: CASZ1_HUMAN Zinc finger protein castor homolog 1 (sprot)

description: A zinc finger protein castor homolog 1 that is encoded in the genome of human.


name: PEX7_HUMAN Peroxisomal targeting signal 2 receptor (sprot)

description: A peroxisomal targeting signal 2 receptor that is encoded in the genome of human.


FMOD_HUMAN Fibromodulin (sprot)

A fibromodulin that is encoded in the genome of human.


name: MOT12_HUMAN Monocarboxylate transporter 12 (sprot)

description: A monocarboxylate transporter 12 that is encoded in the genome of human.


name: PK3CA_HUMAN Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (sprot)

description: A phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform that is encoded in the genome of human.


givinostat

A member of the class of naphthalenes that is naphthalene substituted by ({[4-(hydroxycarbamoyl)phenyl]carbamoyl}oxy)methyl and (diethylamino)methyl groups at positions 2 and 6, respectively. It is a histone deacetylase inhibitor indicated for individuals diagnosed with Duchenne muscular dystrophy.


alosetron

A pyrido[4,3-b]indole compound having a 5-methyl-1H-imidazol-4-ylmethyl group at the 2-position.


CPIN1_HUMAN Anamorsin (sprot)

An anamorsin that is encoded in the genome of human.


apramycin

An aminoglycoside that is 2-deoxystreptamine that is substituted on the oxygen at position 4 by an (8R)-2-amino-8-O-(4-amino-4-deoxy-alpha-D-glucopyranosyl)-2,3,7-trideoxy-7-(methylamino)-D-glycero-alpha-D-allo-octodialdo-1,5:8,4-dipyranos-1-yl) group.


eslicarbazepine acetate

The acetate ester, with S configuration, of licarbazepine. An anticonvulsant, it is approved for use in Europe and the United States as an adjunctive therapy for epilepsy.


Microvesicular hepatic steatosis

category: biolink:PhenotypicFeature biolink:DiseaseOrPhenotypicFeature biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing

description: A form of hepatic steatosis characterized by the presence of small, lipid-laden vesicles in the affected hepatocytes.


name: RARG_HUMAN Retinoic acid receptor gamma (sprot)

description: A retinoic acid receptor gamma that is encoded in the genome of human.


name: MBD4_HUMAN Methyl-CpG-binding domain protein 4 (sprot)

description: A methyl-CpG-binding domain protein 4 that is encoded in the genome of human.


name: FGF3_HUMAN Fibroblast growth factor 3 (sprot)

description: A fibroblast growth factor 3 that is encoded in the genome of human.


name: LAMC2_HUMAN Laminin subunit gamma-2 (sprot)

description: A laminin subunit gamma-2 that is encoded in the genome of human.


name: ERCC1_HUMAN DNA excision repair protein ERCC-1 (sprot)

description: A DNA excision repair protein ERCC-1 that is encoded in the genome of human.


Dysphoria

description: A state of feeling very unhappy, uneasy, or dissatisfied.


MUC13_HUMAN Mucin-13 (sprot)

A mucin-13 that is encoded in the genome of human.


Hypergastrinemia

description: An elevated amount of gastrin in the blood.


name: P3H3_HUMAN Prolyl 3-hydroxylase 3 (sprot)

description: A prolyl 3-hydroxylase 3 that is encoded in the genome of human.


name: ATE1_HUMAN Arginyl-tRNA--protein transferase 1 (sprot)

description: An arginyl-tRNA--protein transferase 1 that is encoded in the genome of human.


CYCLOHEXANOL

An alcohol that consists of cyclohexane bearing a single hydroxy substituent. The parent of the class of cyclohexanols.


name: TIM_HUMAN Protein timeless homolog (sprot)

description: A protein timeless that is encoded in the genome of human.


name: FIL1L_HUMAN Filamin A-interacting protein 1-like (sprot)

description: A filamin A-interacting protein 1-like that is encoded in the genome of human.


PFD1_HUMAN Prefoldin subunit 1 (sprot)

A prefoldin subunit 1 that is encoded in the genome of human.


Hyphema

description: Bleeding in the anterior chamber of the eye.


name: drug rash with eosinophilia and systemic symptoms

description: DRESS syndrome (Drug Rash with Eosinophilia and Systemic Symptoms) is a hypersensitivity reaction characterized by a generalized skin rash, fever, eosinophilia, lymphocytosis and visceral involvement (hepatitis, nephritis, pneumonitis, pericarditis and myocarditis) and, in some patients, reactivation of human herpes virus 6.


RNLS_HUMAN Renalase (sprot)

A renalase that is encoded in the genome of human.


DSG2_HUMAN Desmoglein-2 (sprot)

A desmoglein-2 that is encoded in the genome of human.


hypospadias

description: Hypospadias is the displacement of the urethral meatus on the ventrum of the penis. This abnormality is associated with a varyingly bent, twisted penis and opened dorsal prepuce.


acquired hemophilia A

description: An acquired form of hemophilia A, resulting in spontaneous bleeding in individuals with no history of bleeding disorders. It is believed to be caused by spontaneous inhibition of clotting factor VIII by autoantibodies, and is usually associated with other autoimmune conditions.


name: CXCR6_HUMAN C-X-C chemokine receptor type 6 (sprot)

description: A C-X-C chemokine receptor type 6 that is encoded in the genome of human.


flucytosine

An organofluorine compound that is cytosine that is substituted at position 5 by a fluorine. A prodrug for the antifungal 5-fluorouracil, it is used for the treatment of systemic fungal infections.


name: MD1L1_HUMAN Mitotic spindle assembly checkpoint protein MAD1 (sprot)

description: A mitotic spindle assembly checkpoint protein MAD1 that is encoded in the genome of human.


name: MXI1_HUMAN Max-interacting protein 1 (sprot)

description: A max-interacting protein 1 that is encoded in the genome of human.


name: SPAG1_HUMAN Sperm-associated antigen 1 (sprot)

description: A sperm-associated antigen 1 that is encoded in the genome of human.


betamethasone phosphate

A steroid phosphate that is the 21-O-phospho derivative of betamethasone.


otitis media

description: Inflammation of the anatomical structures of the middle ear, which is most often caused by an infectious process. Symptoms include erythema and edema of the tympanic membrane, pain, and possibly fever.


gout

description: A condition characterized by painful swelling of the joints, which is caused by deposition of urate crystals.


name: ZIC2_HUMAN Zinc finger protein ZIC 2 (sprot)

description: A zinc finger protein ZIC 2 that is encoded in the genome of human.


name: CRDL1_HUMAN Chordin-like protein 1 (sprot)

description: A chordin-like protein 1 that is encoded in the genome of human.


name: SAMH1_HUMAN Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 (sprot)

description: A deoxynucleoside triphosphate triphosphohydrolase SAMHD1 that is encoded in the genome of human.


name: DDX1_HUMAN ATP-dependent RNA helicase DDX1 (sprot)

description: An ATP-dependent RNA helicase DDX1 that is encoded in the genome of human.


name: CDC45_HUMAN Cell division control protein 45 homolog (sprot)

description: A CDC45-related protein that is encoded in the genome of human.


name: SAS10_HUMAN Something about silencing protein 10 (sprot)

description: A something about silencing protein 10 that is encoded in the genome of human.


name: SAS6_HUMAN Spindle assembly abnormal protein 6 homolog (sprot)

description: A spindle assembly abnormal protein 6 that is encoded in the genome of human.


name: SO2B1_HUMAN Solute carrier organic anion transporter family member 2B1 (sprot)

description: A solute carrier organic anion transporter family member 2B1 that is encoded in the genome of human.


brain stem glioma

description: A neuroglial tumor that arises from the brain stem.


name: SIDT2_HUMAN SID1 transmembrane family member 2 (sprot)

description: A SID1 transmembrane family member 2 that is encoded in the genome of human.


trans,trans-farnesyl diphosphate

The trans,trans-stereoisomer of farnesyl diphosphate.


name: CHD7_HUMAN Chromodomain-helicase-DNA-binding protein 7 (sprot)

description: A chromodomain-helicase-DNA-binding protein 7 that is encoded in the genome of human.


name: TBX18_HUMAN T-box transcription factor TBX18 (sprot)

description: A T-box transcription factor TBX18 that is encoded in the genome of human.


name: TR10A_HUMAN Tumor necrosis factor receptor superfamily member 10A (sprot)

description: A tumor necrosis factor receptor superfamily member 10A that is encoded in the genome of human.


name: CRBG1_HUMAN Beta/gamma crystallin domain-containing protein 1 (sprot)

description: A beta/gamma crystallin domain-containing protein 1 that is encoded in the genome of human.


SRCAP_HUMAN Helicase SRCAP (sprot)

A helicase SRCAP that is encoded in the genome of human.


primaquine

An N-substituted diamine that is pentane-1,4-diamine substituted by a 6-methoxyquinolin-8-yl group at the N(4) position. It is a drug used in the treatment of malaria and Pneumocystis pneumonia.


name: WBP11_HUMAN WW domain-binding protein 11 (sprot)

description: A WW domain-binding protein 11 that is encoded in the genome of human.


name: RBBP7_HUMAN Histone-binding protein RBBP7 (sprot)

description: A histone-binding protein RBBP7 that is encoded in the genome of human.


name: intervertebral disk degenerative disorder

description: Any disease of a degenerative nature that affects the intervertebral disk.


tongue cancer

description: A malignant neoplasm affecting the tongue. The vast majority of cases are carcinomas.


name: FHDC1_HUMAN FH2 domain-containing protein 1 (sprot)

description: An FH2 domain-containing protein 1 that is encoded in the genome of human.


name: REPS2_HUMAN RalBP1-associated Eps domain-containing protein 2 (sprot)

description: A RalBP1-associated Eps domain-containing protein 2 that is encoded in the genome of human.


hydronephrosis

description: Collection of urine in the renal pelvis that results in dilatation of the renal pelvis and calyces. It is caused by obstruction of urine flow, nephrolithiasis, or vesicoureteral reflux. Signs and symptoms include flank pain, nausea, vomiting, fever, and dysuria.


Ehlers-Danlos syndrome

description: The Ehlers–Danlos syndromes (EDS) are a clinically and genetically heterogeneous group of heritable connective tissue disorders (HCTDs) characterized by joint hypermobility, skin hyperextensibility, and tissue fragility.


name: CHRD1_HUMAN Cysteine and histidine-rich domain-containing protein 1 (sprot)

description: A cysteine and histidine-rich domain-containing protein 1 that is encoded in the genome of human.


FLNA_HUMAN Filamin-A (sprot)

A filamin-A that is encoded in the genome of human.


name: SOCS7_HUMAN Suppressor of cytokine signaling 7 (sprot)

description: A suppressor of cytokine signaling 7 that is encoded in the genome of human.


ARRS_HUMAN S-arrestin (sprot)

An S-arrestin that is encoded in the genome of human.


pantoprazole

A member of the class of  benzimidazoles that is 1H-benzimidazole substituted by a difluoromethoxy group at position 5 and a [(3,4-dimethoxypyridin-2-yl)methyl]sulfinyl group at position 2.


phosphatidylserine (20:0/20:5)

A phosphatidylserine 40:5 in which the acyl group at C-1 contains 20 carbons and no double bonds while that at C-2 contains 20 carbons and 5 double bonds.


name: GALT_HUMAN Galactose-1-phosphate uridylyltransferase (sprot)

description: A galactose-1-phosphate uridylyltransferase that is encoded in the genome of human.


enteropathy-associated T-cell lymphoma

description: An uncommon mature T-cell lymphoma of intraepithelial lymphocytes. It usually arises from the small intestine, most commonly the jejunum or ileum. Other less frequent primary anatomic sites include the duodenum, stomach, colon, or outside the gastrointestinal tract. It is seen with increased frequency in regions with a high prevalence of celiac disease.


name: RHG04_HUMAN Rho GTPase-activating protein 4 (sprot)

description: A Rho GTPase-activating protein 4 that is encoded in the genome of human.


name: PACN2_HUMAN Protein kinase C and casein kinase substrate in neurons protein 2 (sprot)

description: A protein kinase C and casein kinase substrate in neurons protein 2 that is encoded in the genome of human.


name: DVL1_HUMAN Segment polarity protein dishevelled homolog DVL-1 (sprot)

description: A segment polarity protein dishevelled homolog DVL-1 that is encoded in the genome of human.


name: KAP0_HUMAN cAMP-dependent protein kinase type I-alpha regulatory subunit (sprot)

description: A cAMP-dependent protein kinase type I-alpha regulatory subunit that is encoded in the genome of human.


childhood acute lymphoblastic leukemia

description: An acute lymphoblastic leukemia occurring during childhood. The majority of cases are B-acute lymphoblastic leukemias. Approximately 15% of the cases are T-acute lymphoblastic leukemias.


esophageal cancer

description: A primary or metastatic malignant neoplasm involving the esophagus.


Decreased liver function

description: Reduced ability of the liver to perform its functions.


SYT17_HUMAN Synaptotagmin-17 (sprot)

A synaptotagmin-17 that is encoded in the genome of human.


name: ARI1A_HUMAN AT-rich interactive domain-containing protein 1A (sprot)

description: An AT-rich interactive domain-containing protein 1A that is encoded in the genome of human.


name: EPHA6_HUMAN Ephrin type-A receptor 6 (sprot)

description: An ephrin type-A receptor 6 that is encoded in the genome of human.


Bone pain

description: An unpleasant sensation characterized by physical discomfort (such as pricking, throbbing, or aching) localized to bone.


malonyl-CoA

The S-malonyl derivative of coenzyme A.


COR1B_HUMAN Coronin-1B (sprot)

A coronin-1B that is encoded in the genome of human.


name: TRIM3_HUMAN Tripartite motif-containing protein 3 (sprot)

description: A tripartite motif-containing protein 3 that is encoded in the genome of human.


normocytic anemia

description: Anemia in which the red blood cell volume is normal.


name: CD2_HUMAN T-cell surface antigen CD2 (sprot)

description: A CD2 molecule that is encoded in the genome of human.


tolazoline

A member of the class of imidazoles that is 4,5-dihydro-1H-imidazole substituted by a benzyl group.


name: PLCE1_HUMAN 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 (sprot)

description: A 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 that is encoded in the genome of human.


name: IF2B3_HUMAN Insulin-like growth factor 2 mRNA-binding protein 3 (sprot)

description: An insulin-like growth factor 2 mRNA-binding protein 3 that is encoded in the genome of human.


name: APC1_HUMAN Anaphase-promoting complex subunit 1 (sprot)

description: An anaphase-promoting complex subunit 1 that is encoded in the genome of human.


name: S29A1_HUMAN Equilibrative nucleoside transporter 1 (sprot)

description: An equilibrative nucleoside transporter 1 that is encoded in the genome of human.


PLF4_HUMAN Platelet factor 4 (sprot)

A platelet factor 4 that is encoded in the genome of human.


name: A1CF_HUMAN APOBEC1 complementation factor (sprot)

description: An APOBEC1 complementation factor that is encoded in the genome of human.


betaxolol

A  propanolamine that is 3-aminopropane-1,2-diol in which the hydrogen of the primary hydoxy is substituted by a 4-[2-(cyclopropylmethoxy)ethyl]phenyl group and one of the hydrogens attached to the amino group is substituted by isopropyl. It is a selective  beta1-receptor blocker and is used in the treatment of glaucoma as well as hypertension, arrhythmias, and coronary heart disease. It is also used to reduce non-fatal cardiac events in patients with heart failure.


Erythema migrans

description: An expanding erythematous (red) skin lesion, usually round or oval, by definition at least 5 cm in size (in largest diameter).


name: KAT2A_HUMAN Histone acetyltransferase KAT2A (sprot)

description: A histone acetyltransferase KAT2A that is encoded in the genome of human.


name: COX7C_HUMAN Cytochrome c oxidase subunit 7C, mitochondrial (sprot)

description: A cytochrome c oxidase subunit 7C, mitochondrial that is encoded in the genome of human.


name: BANK1_HUMAN B-cell scaffold protein with ankyrin repeats (sprot)

description: A B-cell scaffold protein with ankyrin repeats that is encoded in the genome of human.


conivaptan

The amide resulting from the formal condensation of 4-[(biphenyl-2-ylcarbonyl)amino]benzoic acid with the benzazepine nitrogen of 2-methyl-1,4,5,6-tetrahydroimidazo[4,5-d][1]benzazepine. It is an antagonist for two of the three types of arginine vasopressin (AVP) receptors, V1a and V2. It is used as its hydrochloride salt for the treatment of hyponatraemia (low blood sodium levels) caused by syndrome of inappropriate antidiuretic hormone (SIADH).


P2RX4_HUMAN P2X purinoceptor 4 (sprot)

A P2X purinoceptor 4 that is encoded in the genome of human.


name: BAF_HUMAN Barrier-to-autointegration factor (sprot)

description: A barrier-to-autointegration factor that is encoded in the genome of human.


name: CCNB3_HUMAN G2/mitotic-specific cyclin-B3 (sprot)

description: A G2/mitotic-specific cyclin-B3 that is encoded in the genome of human.


thymic carcinoma

description: Thymic carcinoma (TC) is a type of thymic epithelial neoplasm characterized by a high malignant potential.


name: ABC3G_HUMAN DNA dC->dU-editing enzyme APOBEC-3G (sprot)

description: A DNA dC->dU-editing enzyme APOBEC-3G that is encoded in the genome of human.


name: HPLN1_HUMAN Hyaluronan and proteoglycan link protein 1 (sprot)

description: A hyaluronan and proteoglycan link protein 1 that is encoded in the genome of human.


corticorelin

A corticotropin-releasing hormone from human/rat composed of Ser, Glu, Glu, Pro, Pro, Ile, Ser, Leu, Asp, Leu, Val, Phe, His, Leu, Leu, Arg, Glu, Val, Leu, Glu, Met, Ala, Arg, Ala, Glu, Gln, Leu, Ala, Gln, Gln, Ala, His, Ser, Asn, Arg, Lys, Leu, Met, Glu, Ile and Ile-NH2 residues joined in sequence.


glycocholate

A cholanic acid conjugate anion that is the conjugate base of glycocholic acid, obtained by deprotonation of the carboxy group; major species at pH 7.3.


etravirine

An aminopyrimidine that consists of 2,6-diaminopyrimidine bearing a bromo substituent at position 5, a 4-cyano-2,6-dimethylphenoxy substituent at position 4 and having a 4-cyanophenyl substituent attached to the 2-amino group. NNRTI of HIV-1, binds directly to RT and blocks RNA-dependent and DNA-dependent DNA polymerase activities


viral hepatitis

description: An acute or chronic inflammation of the liver parenchyma caused by viruses. Representative examples include hepatitis A, B, and C, cytomegalovirus hepatitis, and herpes simplex hepatitis.


name: DNA2_HUMAN DNA replication ATP-dependent helicase/nuclease DNA2 (sprot)

description: A DNA replication ATP-dependent helicase/nuclease DNA2 that is encoded in the genome of human.


ISOCITRATE

A tricarboxylic acid that is propan-1-ol with a hydrogen at each of the 3 carbon positions replaced by a carboxy group.


name: CNNM3_HUMAN Metal transporter CNNM3 (sprot)

description: A metal transporter CNNM3 that is encoded in the genome of human.


name: TP4A2_HUMAN Protein tyrosine phosphatase type IVA 2 (sprot)

description: A protein tyrosine phosphatase type IVA 2 that is encoded in the genome of human.


name: SASH3_HUMAN SAM and SH3 domain-containing protein 3 (sprot)

description: A SAM and SH3 domain-containing protein 3 that is encoded in the genome of human.


name: RMD5A_HUMAN E3 ubiquitin-protein transferase RMND5A (sprot)

description: An E3 ubiquitin-protein transferase RMND5A that is encoded in the genome of human.


catecholamine

4-(2-Aminoethyl)pyrocatechol [4-(2-aminoethyl)benzene-1,2-diol] and derivatives formed by substitution.


name: PZRN3_HUMAN E3 ubiquitin-protein ligase PDZRN3 (sprot)

description: An E3 ubiquitin-protein ligase PDZRN3 that is encoded in the genome of human.


Fulminant hepatitis

description: Acute hepatitis complicated by acute liver failure with hepatic encephalopathy occurring less than 8 weeks after the onset of jaundice.


name: G6PT1_HUMAN Glucose-6-phosphate exchanger SLC37A4 (sprot)

description: A glucose-6-phosphate exchanger SLC37A4 that is encoded in the genome of human.


name: MDC1_HUMAN Mediator of DNA damage checkpoint protein 1 (sprot)

description: A mediator of DNA damage checkpoint protein 1 that is encoded in the genome of human.


name: TRADD_HUMAN Tumor necrosis factor receptor type 1-associated DEATH domain protein (sprot)

description: A tumor necrosis factor receptor type 1-associated DEATH domain protein that is encoded in the genome of human.


name: SNP25_HUMAN Synaptosomal-associated protein 25 (sprot)

description: A synaptosomal-associated protein 25 that is encoded in the genome of human.


diminazene

A triazene derivative that is triazene in which each of the terminal nitrogens is substituted by a 4-carbamimidoylphenyl group.


N-PROPYL BROMIDE

A bromoalkane that is propane carrying a bromo substituent at position 1.


name: GCR_HUMAN Glucocorticoid receptor (sprot)

description: A glucocorticoid receptor that is encoded in the genome of human.


rose bengal (photoactivated)

A xanthene dye that is fluorescein bearing bromine substituents at positions 2', 4', 5' and 7' (on the xanthene ring) and iodine substituents at position 2, 3, 4, and 5 (on the phenyl ring). The dipotassium salt is the biological stain 'rose bengal'.


corneal infection

description: A viral or bacterial infectious process affecting the cornea. Symptoms include pain and redness in the eye, photophobia and eye watering.


name: AT8B2_HUMAN Phospholipid-transporting ATPase ID (sprot)

description: A phospholipid-transporting ATPase ID that is encoded in the genome of human.


name: PSIP1_HUMAN PC4 and SFRS1-interacting protein (sprot)

description: A PC4 and SFRS1-interacting protein that is encoded in the genome of human.


AGO1_HUMAN Protein argonaute-1 (sprot)

A protein argonaute-1 that is encoded in the genome of human.


name: S1PR1_HUMAN Sphingosine 1-phosphate receptor 1 (sprot)

description: A sphingosine 1-phosphate receptor 1 that is encoded in the genome of human.


name: MIS12_HUMAN Protein MIS12 homolog (sprot)

description: A protein MIS12 that is encoded in the genome of human.


NEUM_HUMAN Neuromodulin (sprot)

A neuromodulin that is encoded in the genome of human.


CYGB_HUMAN Cytoglobin (sprot)

A cytoglobin that is encoded in the genome of human.


name: PE2R2_HUMAN Prostaglandin E2 receptor EP2 subtype (sprot)

description: A prostaglandin E2 receptor EP2 subtype that is encoded in the genome of human.


name: HIC1_HUMAN Hypermethylated in cancer 1 protein (sprot)

description: A hypermethylated in cancer 1 protein that is encoded in the genome of human.


name: NMDE2_HUMAN Glutamate receptor ionotropic, NMDA 2B (sprot)

description: A glutamate receptor ionotropic, NMDA 2B that is encoded in the genome of human.


ALS2_HUMAN Alsin (sprot)

An alsin that is encoded in the genome of human.


name: RCC1_HUMAN Regulator of chromosome condensation (sprot)

description: A regulator of chromosome condensation that is encoded in the genome of human.


name: KCNJ8_HUMAN ATP-sensitive inward rectifier potassium channel 8 (sprot)

description: An ATP-sensitive inward rectifier potassium channel 8 that is encoded in the genome of human.


CP2F1_HUMAN Cytochrome P450 2F1 (sprot)

A cytochrome P450 2F1 that is encoded in the genome of human.


name: TIGAR_HUMAN Fructose-2,6-bisphosphatase TIGAR (sprot)

description: A fructose-2,6-bisphosphatase TIGAR that is encoded in the genome of human.


name: AKA12_HUMAN A-kinase anchor protein 12 (sprot)

description: An A-kinase anchor protein 12 that is encoded in the genome of human.


name: RL36A_HUMAN Large ribosomal subunit protein eL42 (sprot)

description: A large ribosomal subunit protein eL42 that is encoded in the genome of human.


name: RL34_HUMAN Large ribosomal subunit protein eL34 (sprot)

description: A large ribosomal subunit protein eL34 that is encoded in the genome of human.


name: SUMO3_HUMAN Small ubiquitin-related modifier 3 (sprot)

description: A small ubiquitin-related modifier 3 that is encoded in the genome of human.


name: PRAG1_HUMAN Inactive tyrosine-protein kinase PRAG1 (sprot)

description: An inactive tyrosine-protein kinase PRAG1 that is encoded in the genome of human.


CASPC_HUMAN Inactive caspase-12 (sprot)

An inactive caspase-12 that is encoded in the genome of human.


name: SF3A2_HUMAN Splicing factor 3A subunit 2 (sprot)

description: A splicing factor 3A subunit 2 that is encoded in the genome of human.


name: SNUT1_HUMAN U4/U6.U5 tri-snRNP-associated protein 1 (sprot)

description: A U4/U6.U5 tri-snRNP-associated protein 1 that is encoded in the genome of human.


name: GALT2_HUMAN Polypeptide N-acetylgalactosaminyltransferase 2 (sprot)

description: A polypeptide N-acetylgalactosaminyltransferase 2 that is encoded in the genome of human.


name: R113B_HUMAN RING finger protein 113B (sprot)

description: A RING finger protein 113B that is encoded in the genome of human.


name: KIF1B_HUMAN Kinesin-like protein KIF1B (sprot)

description: A kinesin-like protein KIF1B that is encoded in the genome of human.


hypertrophic cardiomyopathy

description: A condition in which the myocardium is hypertrophied without an obvious cause. The hypertrophy is generally asymmetric and may be associated with obstruction of the ventricular outflow tract.


dalbavancin

A semisynthetic glycopeptide used for the treatment of acute bacterial skin and skin structure infections caused or suspected to be caused by susceptible isolates of designated Gram-positive microorganisms including MRSA.


name: LIFR_HUMAN Leukemia inhibitory factor receptor (sprot)

description: A leukemia inhibitory factor receptor that is encoded in the genome of human.


name: TM11D_HUMAN Transmembrane protease serine 11D (sprot)

description: A transmembrane protease serine 11D that is encoded in the genome of human.


name: VCX3_HUMAN Variable charge X-linked protein 3 (sprot)

description: A variable charge X-linked protein 3 that is encoded in the genome of human.


name: EXOC7_HUMAN Exocyst complex component 7 (sprot)

description: An exocyst complex component 7 that is encoded in the genome of human.


LATRUNCULIN A

A bicyclic macrolide natural product consisting of a 16-membered bicyclic lactone attached to the rare 2-thiazolidinone moiety. It is obtained from the Red Sea sponge Latrunculia magnifica and from the Fiji Islands sponge Cacospongia mycofijiensis. Latrunculin A inhibits actin polymerisation, microfilament organsation and microfilament-mediated processes.


name: ARP3_HUMAN Actin-related protein 3 (sprot)

description: An actin-related protein 3 that is encoded in the genome of human.


endometriosis

description: The growth of functional endometrial tissue in anatomic sites outside the uterine body. It most often occurs in the pelvic organs.


diamorphine

A morphinane alkaloid that is morphine bearing two acetyl substituents on the O-3 and O-6 positions. As with other opioids, heroin is used as both an analgesic and a recreational drug. Frequent and regular administration is associated with tolerance and physical dependence, which may develop into addiction. Its use includes treatment for acute pain, such as in severe physical trauma, myocardial infarction, post-surgical pain, and chronic pain, including end-stage cancer and other terminal illnesses.


name: CLIC4_HUMAN Chloride intracellular channel protein 4 (sprot)

description: A chloride intracellular channel protein 4 that is encoded in the genome of human.


name: KPCD1_HUMAN Serine/threonine-protein kinase D1 (sprot)

description: A serine/threonine-protein kinase D1 that is encoded in the genome of human.


ribostamycin sulfate

An aminoglycoside sulfate salt resulting from the reaction of ribostamycin  with sulfuric acid.


name: RASF3_HUMAN Ras association domain-containing protein 3 (sprot)

description: A Ras association domain-containing protein 3 that is encoded in the genome of human.


STMN1_HUMAN Stathmin (sprot)

A stathmin that is encoded in the genome of human.


name: OLIG3_HUMAN Oligodendrocyte transcription factor 3 (sprot)

description: An oligodendrocyte transcription factor 3 that is encoded in the genome of human.


name: MBTP1_HUMAN Membrane-bound transcription factor site-1 protease (sprot)

description: A membrane-bound transcription factor site-1 protease that is encoded in the genome of human.


name: GLOD4_HUMAN Glyoxalase domain-containing protein 4 (sprot)

description: A glyoxalase domain-containing protein 4 that is encoded in the genome of human.


name: CEAM5_HUMAN Carcinoembryonic antigen-related cell adhesion molecule 5 (sprot)

description: A carcinoembryonic antigen-related cell adhesion molecule 5 that is encoded in the genome of human.


name: IMB1_HUMAN Importin subunit beta-1 (sprot)

description: An importin subunit beta-1 that is encoded in the genome of human.


congenital fibrosarcoma

description: A fibrosarcoma that occurs in infants. It shares identical morphologic features with adult fibrosarcoma but carries the t(12;15)(p13;q25) translocation that results in ETV6-NTRK3 gene fusion. It usually affects the superficial and deep soft tissues of the extremities. The prognosis is generally much more favorable than for adult fibrosarcoma, and it rarely metastasizes.


name: UBP1_HUMAN Ubiquitin carboxyl-terminal hydrolase 1 (sprot)

description: A ubiquitin carboxyl-terminal hydrolase 1 that is encoded in the genome of human.


name: PS1C2_HUMAN Psoriasis susceptibility 1 candidate gene 2 protein (sprot)

description: A psoriasis susceptibility 1 candidate gene 2 protein that is encoded in the genome of human.


name: GSTA1_HUMAN Glutathione S-transferase A1 (sprot)

description: A glutathione S-transferase A1 that is encoded in the genome of human.


name: GTR5_HUMAN Solute carrier family 2, facilitated glucose transporter member 5 (sprot)

description: A solute carrier family 2, facilitated glucose transporter member 5 that is encoded in the genome of human.


name: ROBO3_HUMAN Roundabout homolog 3 (sprot)

description: A roundabout homolog 3 that is encoded in the genome of human.


methylmalonic acid

A dicarboxylic acid that is malonic acid in which one of the methylene hydrogens is substituted by a methyl group.


name: LZTL1_HUMAN Leucine zipper transcription factor-like protein 1 (sprot)

description: A leucine zipper transcription factor-like protein 1 that is encoded in the genome of human.


name: ADT2_HUMAN ADP/ATP translocase 2 (sprot)

description: An ADP/ATP translocase 2 that is encoded in the genome of human.


corticobasal syndrome

description: Corticobasal syndrome (CBS) is a rare neurodegenerative disease characterized by multifaceted motor system dysfunctions and cognitive defects such as asymmetric rigidity, bradykinesia, limb apraxia, and visuospatial dysfunction.


NADH

A coenzyme found in all living cells; consists of two nucleotides joined through their 5'-phosphate groups, with one nucleotide containing an adenine base and the other containing nicotinamide.


name: KCC2B_HUMAN Calcium/calmodulin-dependent protein kinase type II subunit beta (sprot)

description: A calcium/calmodulin-dependent protein kinase type II subunit beta that is encoded in the genome of human.


microscopic polyangiitis

description: Microscopic polyangiitis (MPA) is an inflammatory, necrotizing, systemic vasculitis that affects predominantly small vessels (i.e. small arteries, arterioles, capillaries, venules) in multiple organs.


name: GAB2_HUMAN GRB2-associated-binding protein 2 (sprot)

description: A GRB2-associated-binding protein 2 that is encoded in the genome of human.


Alstrom syndrome

description: A multisystemic disorder characterized by cone-rod dystrophy, hearing loss, obesity, insulin resistance and hyperinsulinemia, type 2 diabetes mellitus, dilated cardiomyopathy (DCM), and progressive hepatic and renal dysfunction.


cryptogenic organizing pneumonia

description: Cryptogenic organizing pneumonia (COP) is a form of idiopathic interstitial pneumonia characterized pathologically by organizing pneumonia (OP) that presents with non-specific flu-like symptoms, as well as cough and dyspnea and where no etiological agent is found.


ganglioglioma

description: A well differentiated, slow growing neuroepithelial neoplasm composed of neoplastic, mature ganglion cells and neoplastic glial cells. Some gangliogliomas show anaplastic features in their glial component and are considered to be WHO grade III. Rare cases of newly diagnosed gangliogliomas with grade IV (glioblastoma) changes in the glial component have also been reported. (Adapted from WHO)


biliary dyskinesia

description: A motility disorder characterized by biliary colic, absence of gallstones, and an abnormal gallbladder ejection fraction. It is caused by gallbladder dyskinesia and/or sphincter of oddi dysfunction.


name: CUED2_HUMAN CUE domain-containing protein 2 (sprot)

description: A CUE domain-containing protein 2 that is encoded in the genome of human.


name: RS8_HUMAN Small ribosomal subunit protein eS8 (sprot)

description: A small ribosomal subunit protein eS8 that is encoded in the genome of human.


name: C1T9A_HUMAN Complement C1q and tumor necrosis factor-related protein 9A (sprot)

description: A complement C1q and tumor necrosis factor-related protein 9A that is encoded in the genome of human.


lupus nephritis

description: Glomerulonephritis in the context of systemic lupus erythematosus.


SEPIAPTERIN

A sepiapterin with L configuration.


name: CRIP1_HUMAN Cysteine-rich protein 1 (sprot)

description: A cysteine-rich protein 1 that is encoded in the genome of human.


name: ISL2_HUMAN Insulin gene enhancer protein ISL-2 (sprot)

description: An insulin gene enhancer protein ISL-2 that is encoded in the genome of human.


URETHANE

A carbamate ester obtained by the formal condensation of ethanol with carbamic acid. It has been found in alcoholic beverages.


pseudoephedrine

A member of the class of the class of phenylethanolamines that is (1S)-2-(methylamino)-1-phenylethan-1-ol in which the pro-S hydrogen at position 2 is replaced by a methyl group.


name: ORC1_HUMAN Origin recognition complex subunit 1 (sprot)

description: An origin recognition complex subunit 1 that is encoded in the genome of human.


name: ORC2_HUMAN Origin recognition complex subunit 2 (sprot)

description: An origin recognition complex subunit 2 that is encoded in the genome of human.


MATN4_HUMAN Matrilin-4 (sprot)

A matrilin-4 that is encoded in the genome of human.


name: LATS2_HUMAN Serine/threonine-protein kinase LATS2 (sprot)

description: A serine/threonine-protein kinase LATS2 that is encoded in the genome of human.


name: PHOCN_HUMAN MOB-like protein phocein (sprot)

description: A MOB-like protein phocein that is encoded in the genome of human.


active tuberculosis

description: Tuberculosis caused by primary infection of or reactivation of latent Mycobacterium tuberculosis. Active tuberculosis characterized by clinical manifestation and active symptoms compatible with tuberculosis, and is distinct from latent tuberculosis infection that occurs without signs or symptoms of active disease.


nut midline carcinoma

description: A rare, highly aggressive and lethal carcinoma that affects children and young adults. It arises from midline epithelial structures, most commonly the head, neck, and mediastinum. It is a poorly differentiated carcinoma and is characterized by mutations and rearrangement of the NUT gene. A balanced translocation t(15;19) is present that results in the creation of a fusion gene involving the NUT gene, most commonly BRD4-NUT fusion gene.


name: GAS6_HUMAN Growth arrest-specific protein 6 (sprot)

description: A growth arrest-specific protein 6 that is encoded in the genome of human.


isomyristic acid

A branched-chain saturated fatty acid consisting of tridecanoic acid carrying a 12-methyl group.


name: THIM_HUMAN 3-ketoacyl-CoA thiolase, mitochondrial (sprot)

description: A 3-ketoacyl-CoA thiolase, mitochondrial that is encoded in the genome of human.


name: CTR3_HUMAN Cationic amino acid transporter 3 (sprot)

description: A cationic amino acid transporter 3 that is encoded in the genome of human.


name: KIF5C_HUMAN Kinesin heavy chain isoform 5C (sprot)

description: A kinesin heavy chain isoform 5C that is encoded in the genome of human.


name: S22AC_HUMAN Solute carrier family 22 member 12 (sprot)

description: A solute carrier family 22 member 12 that is encoded in the genome of human.


name: CDS1_HUMAN Phosphatidate cytidylyltransferase 1 (sprot)

description: A phosphatidate cytidylyltransferase 1 that is encoded in the genome of human.


spinocerebellar ataxia type 6

description: Spinocerebellar ataxia type 6 (SCA6) is the most common subtype of autosomal dominant cerebellar ataxia type III (ADCA type III) characterized by late-onset and slowly progressive gait ataxia and other cerebellar signs such as impaired muscle coordination and nystagmus.


name: FA8_HUMAN Coagulation factor VIII (sprot)

description: A coagulation factor VIII that is encoded in the genome of human.


name: TRPM7_HUMAN Transient receptor potential cation channel subfamily M member 7 (sprot)

description: A transient receptor potential cation channel subfamily M member 7 that is encoded in the genome of human.


hypotensive disorder

description: Blood pressure that is abnormally low.


name: SP6_HUMAN Transcription factor Sp6 (sprot)

description: A transcription factor Sp6 that is encoded in the genome of human.


nateglinide

An N-acyl-D-phenylalanine resulting from the formal condensation of the amino group of D-phenylalanine with the carboxy group of trans-4-isopropylcyclohexanecarboxylic acid. An orally-administered, rapidly-absorbed, short-acting insulinotropic agent, it is used for the treatment of type 2 diabetes mellitus.


WHIM syndrome 1

description: A congenital autosomal dominant immune deficiency characterized by abnormal retention of mature neutrophils in the bone marrow (myelokathexis) and occasional hypogammaglobulinemia, associated with an increased risk for bacterial infections and a susceptibility to human papillomavirus (HPV) induced lesions (cutaneous warts, genital dysplasia and invasive mucosal carcinoma).


synovial sarcoma

description: Synovial sarcoma is an aggressive soft tissue sarcoma, occurring most commonly in adolescents and young adults (15 to 40 years), usually localized near the large joints of the extremities but also in the head and neck, mediastinum and viscera (lung, kidney etc), clinically presenting as a deep seated swelling or a painful mass often with an initial indolent course and is characterized by its local invasiveness and a propensity to metastasize. The origin of synovial sarcoma is likely from multipotent mesenchymal cells and not synovium (contrary to its name).


lamotrigine

A member of the class of 1,2,4-triazines in which the triazene skeleton is substituted by amino groups at positions 3 and 5, and by a 2,3-dichlorophenyl group at position 6.


name: EIF3E_HUMAN Eukaryotic translation initiation factor 3 subunit E (sprot)

description: A eukaryotic translation initiation factor 3 subunit E that is encoded in the genome of human.


Smith-Magenis syndrome

description: Smith-Magenis syndrome (SMS) is a complex genetic disorder characterized by variable intellectual deficit, sleep disturbance, craniofacial and skeletal anomalies, psychiatric disorders, and speech and motor delay.


name: PEX5R_HUMAN PEX5-related protein (sprot)

description: A PEX5-related protein that is encoded in the genome of human.


perillyl alcohol

A limonene monoterpenoid consists of a cyclohexene ring substituted by a hydroxymethyl  and a prop-1-en-2-yl group at positions 1 and 4 respectively. It is a constituent of a variety of essential oils including lavender.


cabozantinib

A dicarboxylic acid diamide that is N-phenyl-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide in which the hydrogen at position 4 on the phenyl ring is substituted by a (6,7-dimethoxyquinolin-4-yl)oxy group. A multi-tyrosine kinase inhibitor, used (as its malate salt) for the treatment of progressive, metastatic, medullary thyroid cancer.


name: DLX4_HUMAN Homeobox protein DLX-4 (sprot)

description: A homeobox protein DLX-4 that is encoded in the genome of human.


name: INGR2_HUMAN Interferon gamma receptor 2 (sprot)

description: An interferon-gamma receptor beta chain that is encoded in the genome of human.


B-cell neoplasm

description: A group of heterogeneous lymphoid tumors generally expressing one or more B-cell antigens or representing malignant transformations of B-lymphocytes.


name: DAAM1_HUMAN Disheveled-associated activator of morphogenesis 1 (sprot)

description: A disheveled-associated activator of morphogenesis 1 that is encoded in the genome of human.


name: KAT7_HUMAN Histone acetyltransferase KAT7 (sprot)

description: A histone acetyltransferase KAT7 that is encoded in the genome of human.


name: EPHB6_HUMAN Ephrin type-B receptor 6 (sprot)

description: An ephrin type-B receptor 6 that is encoded in the genome of human.


name: EPHB4_HUMAN Ephrin type-B receptor 4 (sprot)

description: An ephrin type-B receptor 4 that is encoded in the genome of human.


cognitive disorder

description: A disease affects cognitive processes.


name: FCRL2_HUMAN Fc receptor-like protein 2 (sprot)

description: An Fc receptor-like protein 2 that is encoded in the genome of human.


MYH6_HUMAN Myosin-6 (sprot)

A myosin-6 that is encoded in the genome of human.


RSPO2_HUMAN R-spondin-2 (sprot)

An R-spondin-2 that is encoded in the genome of human.


name: STEA4_HUMAN Metalloreductase STEAP4 (sprot)

description: A metalloreductase STEAP4 that is encoded in the genome of human.


name: VTCN1_HUMAN V-set domain-containing T-cell activation inhibitor 1 (sprot)

description: A V-set domain-containing T-cell activation inhibitor 1 that is encoded in the genome of human.


thrombocytosis disease

description: A disease characterized by higher than normal platelet counts in the peripheral blood.


Chronic lung disease

description: According to the definitions of the American and British Thoracic Societies, including pulmonary functional tests, X-rays, and CT scans for items such as fibrosis, bronchiectasis, bullae, emphysema, nodular or lymphomatous abnormalities.


AF9_HUMAN Protein AF-9 (sprot)

A protein AF-9 that is encoded in the genome of human.


name: TIM10_HUMAN Mitochondrial import inner membrane translocase subunit Tim10 (sprot)

description: A mitochondrial import inner membrane translocase subunit Tim10 that is encoded in the genome of human.


name: MOGT1_HUMAN 2-acylglycerol O-acyltransferase 1 (sprot)

description: A 2-acylglycerol O-acyltransferase 1 that is encoded in the genome of human.


name: SMUF1_HUMAN E3 ubiquitin-protein ligase SMURF1 (sprot)

description: An E3 ubiquitin-protein ligase SMURF1 that is encoded in the genome of human.


RGMC_HUMAN Hemojuvelin (sprot)

A hemojuvelin that is encoded in the genome of human.


female reproductive organ cancer

description: A primary or metastatic malignant neoplasm involving the female reproductive system. Representative examples include endometrial carcinoma, cervical carcinoma, ovarian carcinoma, uterine corpus leiomyosarcoma, adenosarcoma, malignant mixed mesodermal (mullerian) tumor, and gestational choriocarcinoma.


name: DAPK1_HUMAN Death-associated protein kinase 1 (sprot)

description: A death-associated protein kinase 1 that is encoded in the genome of human.


name: MOT10_HUMAN Monocarboxylate transporter 10 (sprot)

description: A monocarboxylate transporter 10 that is encoded in the genome of human.


name: TSLP_HUMAN Thymic stromal lymphopoietin (sprot)

description: A thymic stromal lymphopoietin that is encoded in the genome of human.


sinefungin

An adenosine that is the the delta-(5'-adenosyl) derivative of ornithine.


anaplastic large cell lymphoma

description: Anaplastic large cell lymphoma (ALCL) is a rare and aggressive peripheral T-cell non-Hodgkin lymphoma, belonging to the group of CD30-positive lymphoproliferative disorders, which affects lymph nodes and extranodal sites. It is comprised of two sub-types, based on the expression of a protein called anaplastic lymphoma kinase (ALK): ALK positive and ALK negative ALCL.


ONALESPIB

A member of the class of isoindoles that is isoindole in which the amino group has been acylated by a 2,4-dihydroxy-5-isopropylbenzoyl group and in which position 5 of the isoidole moiety has been substituted by a (4-methylpiperazin-1-yl)methyl group. A second-generation Hsp90 inhibitor.


neuroendocrine carcinoma

description: A malignant neuroendocrine neoplasm composed of cells containing secretory granules that stain positive for NSE and chromogranin. The neoplastic cells are often round and form clusters or trabecular sheets. Representative examples are small cell carcinoma, large cell neuroendocrine carcinoma, and Merkel cell carcinoma.


chronic obstructive pulmonary disease

description: A chronic and progressive lung disorder characterized by the loss of elasticity of the bronchial tree and the air sacs, destruction of the air sacs wall, thickening of the bronchial wall, and mucous accumulation in the bronchial tree. The pathologic changes result in the disruption of the air flow in the bronchial airways. Signs and symptoms include shortness of breath, wheezing, productive cough, and chest tightness. The two main types of chronic obstructive pulmonary disease are chronic obstructive bronchitis and emphysema.


name: long chain 3-hydroxyacyl-CoA dehydrogenase deficiency

description: Long chain 3-hydroxyacyl-CoA dehydrogenase deficiency (LCHADD) is a mitochondrial disorder of long chain fatty acid oxidation characterized in most patients by onset in infancy/ early childhood with hypoketotic hypoglycemia, metabolic acidosis, liver disease, hypotonia and frequently cardiac involvement with arrhythmias and/or cardiomyopathy.


name: CO3A1_HUMAN Collagen alpha-1(III) chain (sprot)

description: A collagen alpha-1(III) chain that is encoded in the genome of human.


Renal pelvic carcinoma

description: The presence of a carcinoma in the renal pelvis.


tamsulosin

A 5-(2-{[2-(2-ethoxyphenoxy)ethyl]amino}propyl)-2-methoxybenzenesulfonamide that has (R)-configuration. A specific alpha1 adrenoceptor antagonist used (generally as its hydrochloride salt, tamsulosin hydrochloride) in the treatment of prostatic hyperplasia, chronic prostatitis, urinary retention, and help with the passage of kidney stones.


detrusor sphincter dyssynergia

description: A urodynamic anomaly characterized by bladder outlet obstruction from detrusor muscle contraction with concomitant involuntary urethral sphincter activation.


varespladib

A member of the class of indoles that is 1H-indole substituted by benzyl, ethyl, oxamoyl, and carboxymethoxy groups at positions 1, 2, 3, and 4, respectively. It is an oral secretory phospholipase A2 inhibitor and exhibits anti-inflammatory effects.


SGT1_HUMAN Protein SGT1 homolog (sprot)

A protein SGT1 that is encoded in the genome of human.


arsenic acid

An arsenic oxoacid comprising one oxo group and three hydroxy groups attached to a central arsenic atom.


name: COPT1_HUMAN High affinity copper uptake protein 1 (sprot)

description: A high affinity copper uptake protein 1 that is encoded in the genome of human.


methylisothiazolinone

A 1,2-thazole that is 4-isothiazolin-3-one bearing a methyl group on the nitrogen atom. It is a powerful biocide and preservative and is the minor active ingredient in the commercial product Kathon(TM).


lipid pneumonia

description: Pneumonia due to aspiration or inhalation of various oily or fatty substances.


name: UBE2N_HUMAN Ubiquitin-conjugating enzyme E2 N (sprot)

description: A ubiquitin-conjugating enzyme E2 N that is encoded in the genome of human.


Abnormal sperm morphology

description: A structural anomaly of sperm.


fumagillin

A meroterpenoid resulting from the formal condensation of the hydroxy group of fumagillol with the carboxylic acid group of (all-E)-deca-2,4,6,8-tetraenedioic acid. Originally isolated from the fungus Aspergillus fumigatus, it is used for the control of Nosema infection in honey bees.


name: RHBT2_HUMAN Rho-related BTB domain-containing protein 2 (sprot)

description: A Rho-related BTB domain-containing protein 2 that is encoded in the genome of human.


necrobiotic xanthogranuloma

description: A cutaneous necrobiotic disorder characterized by firm, yellow plaques or nodules, often in a periorbital distribution. It is often accompanied by an elevated erythrocyte sedimentation rate; leukopenia; and monoclonal gammopathy (IgG-kappa type) and systemic involvement.


name: Recurrent upper respiratory tract infections

description: An increased susceptibility to upper respiratory tract infections as manifested by a history of recurrent upper respiratory tract infections (running ears - otitis, sinusitis, pharyngitis, tonsillitis).


PENK_HUMAN Proenkephalin-A (sprot)

A proenkephalin-A that is encoded in the genome of human.


tinidazole

1H-imidazole substituted at C-1 by a (2-ethylsulfonyl)ethyl group, at C-2 by a methyl group and at C-5 by a nitro group.  It is used as an antiprotozoal, antibacterial agent.


name: PABP1_HUMAN Polyadenylate-binding protein 1 (sprot)

description: A polyadenylate-binding protein 1 that is encoded in the genome of human.


PUM2_HUMAN Pumilio homolog 2 (sprot)

A pumilio homolog 2 that is encoded in the genome of human.


name: ICAM5_HUMAN Intercellular adhesion molecule 5 (sprot)

description: An intercellular adhesion molecule 5 that is encoded in the genome of human.


name: PEX3_HUMAN Peroxisomal biogenesis factor 3 (sprot)

description: A peroxisomal biogenesis factor 3 that is encoded in the genome of human.


name: DDIT3_HUMAN DNA damage-inducible transcript 3 protein (sprot)

description: A DNA damage-inducible transcript 3 protein that is encoded in the genome of human.


ITB4_HUMAN Integrin beta-4 (sprot)

An integrin beta-4 that is encoded in the genome of human.


name: PPM1D_HUMAN Protein phosphatase 1D (sprot)

description: A protein phosphatase 1D that is encoded in the genome of human.


Lafora disease

description: Lafora disease (LD) is a rare, inherited, severe, progressive myoclonic epilepsy characterized by myoclonus and/or generalized seizures, visual hallucinations (partial occipital seizures), and progressive neurological decline.


lucanthone

A thioxanthen-9-one compound having a methyl substituent at the 1-position and a 2-[(diethylamino)ethyl]amino substituent at the 4-position. Formerly used for the treatment of schistosomiasis. It is a prodrug, being metabolised to hycanthone.


quercetin 3-O-beta-D-glucofuranoside

A quercetin O-glucoside in which a glucofuranosyl residue is attached at position 3 of quercetin via a beta-glycosidic linkage.


name: SPP24_HUMAN Secreted phosphoprotein 24 (sprot)

description: A secreted phosphoprotein 24 that is encoded in the genome of human.


name: LMO4_HUMAN LIM domain transcription factor LMO4 (sprot)

description: A LIM domain transcription factor LMO4 that is encoded in the genome of human.


name: autosomal dominant optic atrophy, classic form

description: One of the most common forms of hereditary optic neuropathy characterized by progressive bilateral visual loss during the first decade of life, associated with optic disk pallor, visual field and color vision defects.


cervical lymphadenitis

description: Inflammation of the cervical lymph nodes.


name: OMA1_HUMAN Metalloendopeptidase OMA1, mitochondrial (sprot)

description: A metalloendopeptidase OMA1, mitochondrial that is encoded in the genome of human.


perflutren

A fluorocarbon that is propane in which all of the hydrogens have been replaced by fluorines.


uterine carcinoma

description: A carcinoma involving a uterus.


name: RAD9A_HUMAN Cell cycle checkpoint control protein RAD9A (sprot)

description: A cell cycle checkpoint control protein RAD9A that is encoded in the genome of human.


name: ACHB2_HUMAN Neuronal acetylcholine receptor subunit beta-2 (sprot)

description: A neuronal acetylcholine receptor subunit beta-2 that is encoded in the genome of human.


name: PAN3_HUMAN PAN2-PAN3 deadenylation complex subunit PAN3 (sprot)

description: A PAN2-PAN3 deadenylation complex subunit PAN3 that is encoded in the genome of human.


name: S36A1_HUMAN Proton-coupled amino acid transporter 1 (sprot)

description: A proton-coupled amino acid transporter 1 that is encoded in the genome of human.


name: PCAT2_HUMAN Lysophosphatidylcholine acyltransferase 2 (sprot)

description: A lysophosphatidylcholine acyltransferase 2 that is encoded in the genome of human.


sulfadiazine

A sulfonamide consisting of pyrimidine with a 4-aminobenzenesulfonamido group at the 2-position.


MYG_HUMAN Myoglobin (sprot)

A myoglobin that is encoded in the genome of human.


MS18B_HUMAN Protein Mis18-beta (sprot)

A protein Mis18-beta that is encoded in the genome of human.


name: ZFYV1_HUMAN Zinc finger FYVE domain-containing protein 1 (sprot)

description: A zinc finger FYVE domain-containing protein 1 that is encoded in the genome of human.


ELAIDIC ACID

A 9-octadecenoic acid and the trans-isomer of oleic acid.


UT1_HUMAN Urea transporter 1 (sprot)

A urea transporter 1 that is encoded in the genome of human.


ITSN2_HUMAN Intersectin-2 (sprot)

An intersectin-2 that is encoded in the genome of human.


name: PK3C3_HUMAN Phosphatidylinositol 3-kinase catalytic subunit type 3 (sprot)

description: A phosphatidylinositol 3-kinase catalytic subunit type 3 that is encoded in the genome of human.


name: CCD93_HUMAN Coiled-coil domain-containing protein 93 (sprot)

description: A coiled-coil domain-containing protein 93 that is encoded in the genome of human.


CASK_HUMAN Kappa-casein (sprot)

A kappa-casein that is encoded in the genome of human.


IL9_HUMAN Interleukin-9 (sprot)

An interleukin-9 that is encoded in the genome of human.


inulin

An inulobiose in which the anomeric centre has beta-configuration.


CYTC_HUMAN Cystatin-C (sprot)

A cystatin-C that is encoded in the genome of human.


name: TRI33_HUMAN E3 ubiquitin-protein ligase TRIM33 (sprot)

description: An E3 ubiquitin-protein ligase TRIM33 that is encoded in the genome of human.


name: TRI32_HUMAN E3 ubiquitin-protein ligase TRIM32 (sprot)

description: An E3 ubiquitin-protein ligase TRIM32 that is encoded in the genome of human.


PLINABULIN

A member of the class of 2,5-diketopiperazines that is piperazine-2,5-dione substituted by benzylidene and (5-tert-butyl-1H-imidazol-4-yl)methylidene groups at positions 3 and 6, respectively. It is a vascular disrupting agent and a microtubule destabalising agent which was in clinical trials (now discontinued) for the treatment of non-small cell lung cancer.


SORT_HUMAN Sortilin (sprot)

A sortilin that is encoded in the genome of human.


name: SLIT1_HUMAN Slit homolog 1 protein (sprot)

description: A slit homolog 1 protein that is encoded in the genome of human.


name: ROBO2_HUMAN Roundabout homolog 2 (sprot)

description: A roundabout homolog 2 that is encoded in the genome of human.


name: PDIA4_HUMAN Protein disulfide-isomerase A4 (sprot)

description: A protein disulfide-isomerase A4 that is encoded in the genome of human.


name: ACER2_HUMAN Alkaline ceramidase 2 (sprot)

description: An alkaline ceramidase 2 that is encoded in the genome of human.


B-cell non-Hodgkin lymphoma

description: The most common type of non-Hodgkin lymphoma. It includes the most frequently seen morphologic variants which are: diffuse large B-cell lymphoma, follicular lymphoma, small lymphocytic lymphoma and marginal zone B-cell lymphoma. -- 2003


childhood absence epilepsy

description: A familial generalized pediatric epilepsy, characterized by very frequent (multiple per day) absence seizures, usually occurring in children between the ages of 4 and 10 years, with, in most cases, a good prognosis.


name: AP2E_HUMAN Transcription factor AP-2-epsilon (sprot)

description: A transcription factor AP-2-epsilon that is encoded in the genome of human.


TSN6_HUMAN Tetraspanin-6 (sprot)

A tetraspanin-6 that is encoded in the genome of human.


name: GIMA5_HUMAN GTPase IMAP family member 5 (sprot)

description: A GTPase IMAP family member 5 that is encoded in the genome of human.


name: PEO1_HUMAN Twinkle mtDNA helicase (sprot)

description: A twinkle mtDNA helicase that is encoded in the genome of human.


ATX8_HUMAN Ataxin-8 (sprot)

An ataxin-8 that is encoded in the genome of human.


phosphatidylserine (18:0/22:5)

A phosphatidylserine 40:5 in which the acyl group at C-1 contains 18 carbons and no double bonds while that at C-2 contains 22 carbons and 5 double bonds.


name: SPSB2_HUMAN SPRY domain-containing SOCS box protein 2 (sprot)

description: A SPRY domain-containing SOCS box protein 2 that is encoded in the genome of human.


acetohydroxamic acid

A member of the class of acetohydroxamic acids that is acetamide in which one of the amino hydrogens has been replaced by a hydroxy group.


name: PTPRC_HUMAN Receptor-type tyrosine-protein phosphatase C (sprot)

description: A receptor-type tyrosine-protein phosphatase C that is encoded in the genome of human.


name: GPR37_HUMAN Prosaposin receptor GPR37 (sprot)

description: A prosaposin receptor GPR37 that is encoded in the genome of human.


name: SORL_HUMAN Sortilin-related receptor (sprot)

description: A sortilin-related receptor that is encoded in the genome of human.


name: CXXC5_HUMAN CXXC-type zinc finger protein 5 (sprot)

description: A CXXC-type zinc finger protein 5 that is encoded in the genome of human.


decanoic acid

A C10, straight-chain saturated fatty acid.


name: MPRI_HUMAN Cation-independent mannose-6-phosphate receptor (sprot)

description: A cation-independent mannose-6-phosphate receptor that is encoded in the genome of human.


IWS1_HUMAN Protein IWS1 homolog (sprot)

A protein IWS1 that is encoded in the genome of human.


name: SSRP1_HUMAN FACT complex subunit SSRP1 (sprot)

description: A FACT complex subunit SSRP1 that is encoded in the genome of human.


Low-grade fever

description: Mild fever that does not exceed 38.5 degrees centigrade.


name: CP2CI_HUMAN Cytochrome P450 2C18 (sprot)

description: A cytochrome P450 2C18 that is encoded in the genome of human.


name: KPCD3_HUMAN Serine/threonine-protein kinase D3 (sprot)

description: A serine/threonine-protein kinase D3 that is encoded in the genome of human.


brequinar

A quinolinemonocarboxylic acid that is quinoline substituted by 2'-fluoro[1,1'-biphenyl]-4-yl, methyl, carboxy and fluoro groups at positions 2, 3, 4, and 6, respectively. It is an inhibitor of dihydroorotate dehydrogenase, an enzyme that is required for de novo pyrimidine biosynthesis. The compound exhibits antineoplastic and antiviral properties.


name: PRS7_HUMAN 26S proteasome regulatory subunit 7 (sprot)

description: A 26S proteasome regulatory subunit 7 that is encoded in the genome of human.


name: RDH14_HUMAN Retinol dehydrogenase 14 (sprot)

description: A retinol dehydrogenase 14 that is encoded in the genome of human.


Fanconi anemia

description: Fanconi anemia (FA) is a hereditary DNA repair disorder characterized by progressive pancytopenia with bone marrow failure, variable congenital malformations and predisposition to develop hematological or solid tumors.


teriflunomide

An  enamide obtained by formal condensation of the carboxy group of (2Z)-2-cyano-3-hydroxybut-2-enoic acid with the anilino group of 4-(trifluoromethyl)aniline. Used for the treatment of relapsing forms of multiple sclerosis and rheumatoid arthritis.


aortic valve disease 1

description: Any aortic valve disease in which the cause of the disease is a mutation in the NOTCH1 gene.


TRBM_HUMAN Thrombomodulin (sprot)

A thrombomodulin that is encoded in the genome of human.


MUC6_HUMAN Mucin-6 (sprot)

A mucin-6 that is encoded in the genome of human.


name: ABCA5_HUMAN Cholesterol transporter ABCA5 (sprot)

description: A cholesterol transporter ABCA5 that is encoded in the genome of human.


dysthymic disorder

description: A chronic mood disorder in which the symptoms are similar to, though milder than, those diagnosed in depression.


leukopenia

description: A laboratory test result indicating a decreased number of white blood cells in the peripheral blood.


name: diffuse leptomeningeal glioneuronal tumor

description: A central nervous system benign neoplasm that is characterized by the presence of clear glial neoplastic cells reminiscent of oligodendroglioma.


Immune dysregulation

description: Altered immune function characterized by lymphoid proliferation, immune activation, and excessive autoreactivity often leading to autoimmune/inflammatory complications.


name: CA2D3_HUMAN Voltage-dependent calcium channel subunit alpha-2/delta-3 (sprot)

description: A voltage-dependent calcium channel subunit alpha-2/delta-3 that is encoded in the genome of human.


amnestic disorder

description: Systematic and extensive loss of memory caused by organic or psychological factors. The loss may be temporary or permanent, and may involve old or recent memories.


SODIUM BISULFITE

An inorganic sodium salt having hydrogensulfite as the counterion.


name: ABC3B_HUMAN DNA dC->dU-editing enzyme APOBEC-3B (sprot)

description: A DNA dC->dU-editing enzyme APOBEC-3B that is encoded in the genome of human.


name: UBP44_HUMAN Ubiquitin carboxyl-terminal hydrolase 44 (sprot)

description: A ubiquitin carboxyl-terminal hydrolase 44 that is encoded in the genome of human.


sizofiran

An exopolysaccharide produced by the basidiomycete Schizophyllum commune, consisting of a 1,3-beta-D-glucan backbone with 1,6-beta-D-glucosyl side chains; a multipurpose compound applicable in many fields, including the food industry and pharmacy.


name: DKK3_HUMAN Dickkopf-related protein 3 (sprot)

description: A dickkopf-related protein 3 that is encoded in the genome of human.


name: FSP1_HUMAN Ferroptosis suppressor protein 1 (sprot)

description: A ferroptosis suppressor protein 1 that is encoded in the genome of human.


tasquinimod

Tasquinimod is a quinoline-3-carboxamide linomide analogue with antiangiogenic and potential antineoplastic activities. Tasquinimod has been shown to decrease blood vessel density but the exact mechanism of action is not known. This agent has also been shown to augment the antineoplastic effects of docetaxel and androgen ablation in a murine model of prostate cancer involving human prostate cancer xenografts.


optic nerve disorder

description: A non-neoplastic or neoplastic disorder affecting the optic nerve (second cranial nerve).


oxybenzone

A hydroxybenzophenone that is benzophenone which is substituted at the 2- and 4-positions of one of the benzene rings by hydroxy and methoxy groups respectively.


name: SCO1_HUMAN Protein SCO1 homolog, mitochondrial (sprot)

description: A protein SCO1, mitochondrial that is encoded in the genome of human.


P73_HUMAN Tumor protein p73 (sprot)

A tumor protein p73 that is encoded in the genome of human.


P2RY1_HUMAN P2Y purinoceptor 1 (sprot)

A P2Y purinoceptor 1 that is encoded in the genome of human.


name: MZB1_HUMAN Marginal zone B- and B1-cell-specific protein (sprot)

description: A proapoptotic caspase adapter protein that is encoded in the genome of human.


name: TNNT2_HUMAN Troponin T, cardiac muscle (sprot)

description: A troponin T, cardiac muscle that is encoded in the genome of human.


name: IF172_HUMAN Intraflagellar transport protein 172 homolog (sprot)

description: An intraflagellar transport protein 172 that is encoded in the genome of human.


name: PSMD6_HUMAN 26S proteasome non-ATPase regulatory subunit 6 (sprot)

description: A 26S proteasome non-ATPase regulatory subunit 6 that is encoded in the genome of human.


name: PSF1_HUMAN DNA replication complex GINS protein PSF1 (sprot)

description: A DNA replication complex GINS protein PSF1 that is encoded in the genome of human.


name: SPSB1_HUMAN SPRY domain-containing SOCS box protein 1 (sprot)

description: A SPRY domain-containing SOCS box protein 1 that is encoded in the genome of human.


anorexia nervosa

description: A disorder most often seen in adolescent females characterized by a refusal to maintain a minimally normal body weight, an intense fear of gaining weight, a disturbance in body image, and, in postmenarcheal females, the development of amenorrhea.


name: NPC2_HUMAN NPC intracellular cholesterol transporter 2 (sprot)

description: An NPC intracellular cholesterol transporter 2 that is encoded in the genome of human.


tesamorelin

A polypeptide that is a synthetic analogue of human GRF (Growth Releasing Factor) comprised of the 44 amino-acid sequence of human GRF with a hex-3-enoyl moiety attached to the tyrosine residue at the N-terminal part of the molecule. It is used to stimulate human GRF receptors.


RASPBERRYKETONE

A ketone that is 4-phenylbutan-2-one in which the phenyl ring is substituted at position 4 by a hydroxy group. It is found in a variety of fruits including raspberries, blackberries and cranberries, and is used in perfumery and cosmetics.


name: ASIC1_HUMAN Acid-sensing ion channel 1 (sprot)

description: An acid-sensing ion channel 1 that is encoded in the genome of human.


name: PGDH_HUMAN 15-hydroxyprostaglandin dehydrogenase [NAD(+)] (sprot)

description: A 15-hydroxyprostaglandin dehydrogenase [NAD(+)] that is encoded in the genome of human.


PROF1_HUMAN Profilin-1 (sprot)

A profilin-1 that is encoded in the genome of human.


name: FOXA3_HUMAN Hepatocyte nuclear factor 3-gamma (sprot)

description: A hepatocyte nuclear factor 3-gamma that is encoded in the genome of human.


name: DDX46_HUMAN Probable ATP-dependent RNA helicase DDX46 (sprot)

description: A probable ATP-dependent RNA helicase DDX46 that is encoded in the genome of human.


name: PRP16_HUMAN Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 (sprot)

description: A pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 that is encoded in the genome of human.


name: GLI3_HUMAN Transcriptional activator GLI3 (sprot)

description: A transcriptional activator GLI3 that is encoded in the genome of human.


NMS_HUMAN Neuromedin-S (sprot)

A neuromedin-S that is encoded in the genome of human.


name: BCL10_HUMAN B-cell lymphoma/leukemia 10 (sprot)

description: A B-cell lymphoma/leukemia 10 that is encoded in the genome of human.


SODIUM ARSENITE

An inoganic sodium salt with formula with formula NaAsO2.


name: G3BP1_HUMAN Ras GTPase-activating protein-binding protein 1 (sprot)

description: A Ras GTPase-activating protein-binding protein 1 that is encoded in the genome of human.


name: TP8L1_HUMAN Tumor necrosis factor alpha-induced protein 8-like protein 1 (sprot)

description: A tumor necrosis factor alpha-induced protein 8-like protein 1 that is encoded in the genome of human.


name: MPPB_HUMAN Mitochondrial-processing peptidase subunit beta (sprot)

description: A mitochondrial-processing peptidase subunit beta that is encoded in the genome of human.


name: SAMP_HUMAN Serum amyloid P-component (sprot)

description: A serum amyloid P-component that is encoded in the genome of human.


TRAUMATIC ACID

A monounsaturated straight-chain dicarboxylic acid with the double bond at C-2; a plant wound-healing hormone.


name: I13R2_HUMAN Interleukin-13 receptor subunit alpha-2 (sprot)

description: An interleukin-13 receptor subunit alpha-2 that is encoded in the genome of human.


name: MPC1_HUMAN Mitochondrial pyruvate carrier 1 (sprot)

description: A brain protein 44-like protein that is encoded in the genome of human.


Polyphagia

description: A neurological anomaly with gross overeating associated with an abnormally strong desire or need to eat.


name: EXOC3_HUMAN Exocyst complex component 3 (sprot)

description: An exocyst complex component 3 that is encoded in the genome of human.


name: CP21A_HUMAN Steroid 21-hydroxylase (sprot)

description: A steroid 21-hydroxylase that is encoded in the genome of human.


name: ACKR4_HUMAN Atypical chemokine receptor 4 (sprot)

description: An atypical chemokine receptor 4 that is encoded in the genome of human.


cacodylic acid

The organoarsenic compound that is arsenic acid substituted on the central arsenic atom with two methyl groups.


name: FABPH_HUMAN Fatty acid-binding protein, heart (sprot)

description: A fatty acid-binding protein, heart that is encoded in the genome of human.


methylprednisolone acetate

An acetate ester resulting from the formal condensation of the 21-hydroxy function of 6alpha-methylprednisolone compound with acetic acid.


strychnine

A monoterpenoid indole alkaloid that is strychnidine bearing a keto substituent at the 10-position.


Acute hepatitis

description: Acute hepatic injury resulting from inflammation typically accompanied by increased serum alanine transaminase activity. Etiologies include viral hepatitis, drugs, toxins, and autoimmune disorders.


hyperprolactinemia

description: Abnormally high level of prolactin in the blood.


MATAIRESINOL

A lignan that is gamma-butyrolactone in which the 3 and 4 positions are substituted by 4-hydroxy-3-methoxybenzyl groups (the 3R,4R-diastereomer).


name: GRIK1_HUMAN Glutamate receptor ionotropic, kainate 1 (sprot)

description: A glutamate receptor ionotropic, kainate 1 that is encoded in the genome of human.


name: CNTP2_HUMAN Contactin-associated protein-like 2 (sprot)

description: A contactin-associated protein-like 2 that is encoded in the genome of human.


mastitis

description: Inflammation of breast tissue during lactation or postpartum due to an obstructed duct or infection. Mastitis can also occur in non-breastfeeding women, and rarely in men.


quinine sulfate

A organic sulfate salt obtained from guanethidine and sulfuric acid in a 2:1 ratio.


baricitinib

A pyrrolopyrimidine that is 7H-pyrrolo[2,3-d]pyrimidine substituted by a 1-[3-(cyanomethyl)-1-(ethanesulfonyl)azetidin-3-yl]-1H-pyrazol-4-yl group at position 5. It is an FDA approved selective Janus Kinase 1 and 2 (JAK1 and JAK2) inhibitor used for the treatment of rheumatoid arthritis.


name: P121C_HUMAN Nuclear envelope pore membrane protein POM 121C (sprot)

description: A nuclear envelope pore membrane protein POM 121C that is encoded in the genome of human.


name: DIRA3_HUMAN GTP-binding protein Di-Ras3 (sprot)

description: A GTP-binding protein Di-Ras3 that is encoded in the genome of human.


inflammatory bowel disease

description: A spectrum of small and large bowel inflammatory diseases of unknown etiology. It includes Crohn's disease, ulcerative colitis, and colitis of indeterminate type.


Positive lupus band test

description: Deposits of immunoglobulins and complement components along the dermoepidermal junction.


phosphatidylcholine (18:0/20:4)

A phosphatidylcholine 38:4 in which the fatty acyl groups at positions 1 and 2 are specified as C18:0 and C20:4 respectively.


name: SIAT9_HUMAN Lactosylceramide alpha-2,3-sialyltransferase (sprot)

description: A lactosylceramide alpha-2,3-sialyltransferase that is encoded in the genome of human.


name: AP3B1_HUMAN AP-3 complex subunit beta-1 (sprot)

description: An AP-3 complex subunit beta-1 that is encoded in the genome of human.


name: TBA1C_HUMAN Tubulin alpha-1C chain (sprot)

description: A tubulin alpha-1C chain that is encoded in the genome of human.


name: DDX6_HUMAN Probable ATP-dependent RNA helicase DDX6 (sprot)

description: A probable ATP-dependent RNA helicase DDX6 that is encoded in the genome of human.


name: GDF6_HUMAN Growth/differentiation factor 6 (sprot)

description: A growth/differentiation factor 6 that is encoded in the genome of human.


dabigatran etexilate

An aromatic amide obtained by formal condensation of the carboxy group of 2-{[(4-{N'-[(hexyloxy)carbonyl]carbamimidoyl}phenyl)amino]methyl}-1-methyl-1H-benzimidazole-5-carboxylic acid with the secondary amino group of ethyl N-pyridin-2-yl-beta-alaninate. A prodrug for dabigatran, a thrombin inhibitor and anticoagulant which is used for the prevention of stroke and systemic embolism.


name: GPR20_HUMAN G-protein coupled receptor 20 (sprot)

description: A G-protein coupled receptor 20 that is encoded in the genome of human.


CALD1_HUMAN Caldesmon (sprot)

A caldesmon that is encoded in the genome of human.


nitrous oxide

A nitrogen oxide consisting of linear unsymmetrical molecules with formula N2O. While it is the most used gaseous anaesthetic in the world, its major commercial use, due to its solubility under pressure in vegetable fats combined with its non-toxicity in low concentrations, is as an aerosol spray propellant and aerating agent for canisters of 'whipped' cream.


trovafloxacin

A 1,8-naphthyridine derivative that is 4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid bearing additional 2,4-difluorophenyl, fluoro and  6-amino-3-azabicyclo[3.1.0]hex-3-yl substituents at positions 1, 6 and 7 respectively. A broad-spectrum antibiotic that was withdrawn from the market due to risk of liver failure.


name: estrogen-receptor positive breast cancer

description: A subtype of breast cancer that is estrogen-receptor positive


pneumocystosis

description: Human pneumocystosis is caused by an infectious agent, which (after recent nomenclature and taxonomy revisions) is now classed as the fungus Pneumocystis jiroveci. The prevalence is unknown. Pneumocystis jiroveci is an opportunistic infectious agent, developing in immunosuppressed patients. It is an air-borne infection, localized to the lungs. However, extrapulmonary involvement is seen in AIDS patients. The disease manifests progressively with coughing, respiratory problems (dyspnea) and fever, followed by acute respiratory insufficiency and death within a few weeks in untreated cases. The most reliable diagnostic method is bronchoalveolar lavage. The treatment of choice is cotrimoxazole.


icatibant

A ten-membered synthetic oligopeptide consisting of D-Arg, Arg, Pro, Hyp, Gly, Thi, Ser, D-Tic, Oic, and Arg residues joined in sequrence. A bradykinin receptor antagonist used as its acetate salt for the treatment of acute attacks of hereditary angioedema in adult patients.


KLK4_HUMAN Kallikrein-4 (sprot)

A kallikrein-4 that is encoded in the genome of human.


COL10_HUMAN Collectin-10 (sprot)

A collectin-10 that is encoded in the genome of human.


name: KPCD2_HUMAN Serine/threonine-protein kinase D2 (sprot)

description: A serine/threonine-protein kinase D2 that is encoded in the genome of human.


CASP8_HUMAN Caspase-8 (sprot)

A caspase-8 that is encoded in the genome of human.


SRR_HUMAN Serine racemase (sprot)

A serine racemase that is encoded in the genome of human.


name: EWS_HUMAN RNA-binding protein EWS (sprot)

description: An RNA-binding protein EWS that is encoded in the genome of human.


Wilson disease

description: A very rare inherited multisystemic disease presenting non-specific neurological, hepatic, psychiatric or osseo-muscular manifestations due to excessive copper deposition in the body.


name: PADI4_HUMAN Protein-arginine deiminase type-4 (sprot)

description: A protein-arginine deiminase type-4 that is encoded in the genome of human.


name: UHRF1_HUMAN E3 ubiquitin-protein ligase UHRF1 (sprot)

description: An E3 ubiquitin-protein ligase UHRF1 that is encoded in the genome of human.


name: TACC3_HUMAN Transforming acidic coiled-coil-containing protein 3 (sprot)

description: A transforming acidic coiled-coil-containing protein 3 that is encoded in the genome of human.


central pontine myelinolysis

description: A central nervous system disorder caused by demyelination within the central basis pontis of the brain. It is characterized by spastic quadriplegia, pseudobulbar palsy and encephalopathy. It is observed in patients with severe hyponatremia, particularly when the hyponatremia is corrected too rapidly.


phosphine oxide

Phosphine oxides are organophosphorus compounds with the formula OPR3, where R = alkyl or aryl. They are considered to be the most stable organophosphorus compounds.


name: PTPRT_HUMAN Receptor-type tyrosine-protein phosphatase T (sprot)

description: A receptor-type tyrosine-protein phosphatase T that is encoded in the genome of human.


name: PLGF_HUMAN Placenta growth factor (sprot)

description: A placenta growth factor that is encoded in the genome of human.


name: ARAP1_HUMAN Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 (sprot)

description: An Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 that is encoded in the genome of human.


Renal tubular atrophy

description: The presence of renal tubules with thick redundant basement membranes, or a reduction of greater than 50% in tubular diameter compared to surrounding non-atrophic tubules.


ouabain

A steroid hormone that is a multi-hydroxylated alpha-L-rhamnosyl cardenoloide. It binds to and inhibits the plasma membrane Na(+)/K(+)-ATPase (sodium pump). It has been isolated naturally from Strophanthus gratus.


CCKN_HUMAN Cholecystokinin (sprot)

A cholecystokinin that is encoded in the genome of human.


EGLN1_HUMAN Egl nine homolog 1 (sprot)

An egl nine homolog 1 that is encoded in the genome of human.


name: PAR4_HUMAN Proteinase-activated receptor 4 (sprot)

description: A proteinase-activated receptor 4 that is encoded in the genome of human.


rottlerin

A chromenol that is 2,2-dimethyl-2H-chromene substituted by hydroxy groups at positions 5 and 7, a 3-acetyl-2,4,6-trihydroxy-5-methylbenzyl group at position 6 and a (1E)-3-oxo-1-phenylprop-1-en-3-yl group at position 8. A potassium channel opener, it is isolated from Mallotus philippensis.


methoxamine

An amphetamine in which the parent 1-phenylpropan-2-amine skeleton is substituted at position 1 with an hydroxy group and the phenyl ring is 2- and 5-substituted with methoxy groups. It is an antihypotensive agent (pressor), an agonist acting directly at alpha-adrenoceptors with selectivity for the alpha-1 adrenoceptor subtype similar to phenylephrine .


RACEMETHIONINE

A sulfur-containing amino acid that is butyric acid bearing an amino substituent at position 2 and a methylthio substituent at position 4.


name: AAAT_HUMAN Neutral amino acid transporter B(0) (sprot)

description: A neutral amino acid transporter B(0) that is encoded in the genome of human.


favipiravir

A member of the class of pyrazines that is pyrazine substituted by aminocarbonyl, hydroxy and fluoro groups at positions 2, 3 and 6, respectively. It is an anti-viral agent that inhibits RNA-dependent RNA polymerase of several RNA viruses and is approved for the treatment of influenza in Japan.


An endocannabinoid and an endogenous agonist of the cannabinoid receptors (CB1 and CB2). It is an ester formed from omega-6-arachidonic acid and glycerol.


name: SMS2_HUMAN Phosphatidylcholine:ceramide cholinephosphotransferase 2 (sprot)

description: A phosphatidylcholine:ceramide cholinephosphotransferase 2 that is encoded in the genome of human.


name: TXTP_HUMAN Tricarboxylate transport protein, mitochondrial (sprot)

description: A tricarboxylate transport protein, mitochondrial that is encoded in the genome of human.


primary adrenal insufficiency

description: A hormonal disorder that occurs when the adrenal glands fail to release adequate amounts of glucocorticoids (cortisol), mineralocorticoids (aldosterone, 11-deoxycorticosterone), and androgens (dehydroepiandrosterone) to meet physiologic needs, despite release of ACTH from the pituitary.


Neutrophilia

description: Increased number of neutrophils circulating in blood.


name: NFYA_HUMAN Nuclear transcription factor Y subunit alpha (sprot)

description: A nuclear transcription factor Y subunit alpha that is encoded in the genome of human.


XPO5_HUMAN Exportin-5 (sprot)

An exportin-5 that is encoded in the genome of human.


name: PMYT1_HUMAN Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (sprot)

description: A membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase that is encoded in the genome of human.


name: LAMA1_HUMAN Laminin subunit alpha-1 (sprot)

description: A laminin subunit alpha-1 that is encoded in the genome of human.


name: MYO1F_HUMAN Unconventional myosin-If (sprot)

description: A myosin-If that is encoded in the genome of human.


name: MYO5A_HUMAN Unconventional myosin-Va (sprot)

description: A myosin-Va that is encoded in the genome of human.


choroid plexus papilloma

description: Papilloma of the choroid plexus is a rare benign type of choroid plexus tumor, accounting for 1% of all brain tumors, often occurring in the fourth ventricle (in adults) and the lateral ventricle (in children) but sometimes arising ectopically in the brain parenchyma, and presenting with nausea, vomiting, papilledema, abnormal eye movements, as well as enlarged head circumference, seizures and gait impairment due to an increase in intracranial pressure.


name: S20A1_HUMAN Sodium-dependent phosphate transporter 1 (sprot)

description: A sodium-dependent phosphate transporter 1 that is encoded in the genome of human.


name: SIX6_HUMAN Homeobox protein SIX6 (sprot)

description: A homeobox protein SIX6 that is encoded in the genome of human.


name: IFIT2_HUMAN Interferon-induced protein with tetratricopeptide repeats 2 (sprot)

description: An interferon-induced protein with tetratricopeptide repeats 2 that is encoded in the genome of human.


streptococcal pneumonia

description: A febrile disease caused by streptococcus pneumoniae.


TRIPTONIDE

A diterpene triepoxide that is triptobenzene K in which the acylhydroquinone moiety has undergone oxidation to the corresponding triepoxyketone derivative. It has been isolated from the roots of Tripterygium wilfordii.


name: SPEM1_HUMAN Spermatid maturation protein 1 (sprot)

description: A spermatid maturation protein 1 that is encoded in the genome of human.


name: SCML2_HUMAN Sex comb on midleg-like protein 2 (sprot)

description: A sex comb on midleg-like protein 2 that is encoded in the genome of human.


name: RIR1_HUMAN Ribonucleoside-diphosphate reductase large subunit (sprot)

description: A ribonucleoside-diphosphate reductase large subunit that is encoded in the genome of human.


name: CCL8_HUMAN C-C motif chemokine 8 (sprot)

description: A C-C motif chemokine 8 that is encoded in the genome of human.


name: METK1_HUMAN S-adenosylmethionine synthase isoform type-1 (sprot)

description: An S-adenosylmethionine synthetase isoform type-1 that is encoded in the genome of human.


name: MAT1_HUMAN CDK-activating kinase assembly factor MAT1 (sprot)

description: A CDK-activating kinase assembly factor MAT1 that is encoded in the genome of human.


ALPHA-PINENE

A pinene that is bicyclo[3.1.1]hept-2-ene substituted by methyl groups at positions 2, 6 and 6 respectively.


name: PRPC_HUMAN Salivary acidic proline-rich phosphoprotein 1/2 (sprot)

description: A salivary acidic proline-rich phosphoprotein that is encoded in the genome of human.


ranolazine

A racemate comprising equal amounts of (R)- and (S)-ranolazine. Used for treatment of chronic angina.


Cardiac amyloidosis

description: Extracellular deposition in cardiac tissue of a proteinaceous material that, when stained with Congo red, demonstrates apple-green birefringence under polarized light and that has a distinct color when stained with sulfated Alcian blue. Viewed with electron microscopy, the amyloid deposits are seen to be composed of a beta-sheet fibrillar material. These nonbranching fibrils have a diameter of 7.5 to 10 nm and are the result of protein misfolding.


3,5-di-O-caffeoyl quinic acid

A carboxylic ester that is the diester obtained by the condensation of the hydroxy groups at positions 3 and 5 of (-)-quinic acid with the carboxy group of trans-caffeic acid. Isolated from Brazilian propolis and Suaeda glauca, it exhibits hepatoprotective and cytotoxic activities.


name: EXOSX_HUMAN Exosome complex component 10 (sprot)

description: An exosome complex component 10 that is encoded in the genome of human.


name: Epstein-Barr virus-associated malignant lymphoproliferative disorder

description: A lymphoproliferative disorder associated with Epstein-Barr virus. This category includes, but is not limited to, Burkitt lymphoma, classic Hodgkin lymphoma, and lymphomas arising in immunocompromised individuals.


name: NEIL3_HUMAN Endonuclease 8-like 3 (sprot)

description: An endonuclease 8-like 3 that is encoded in the genome of human.


hemophilia A

description: The most common form of hemophilia characterized by spontaneous or prolonged hemorrhages due to factor VIII deficiency.


name: SHPRH_HUMAN E3 ubiquitin-protein ligase SHPRH (sprot)

description: An E3 ubiquitin-protein ligase SHPRH that is encoded in the genome of human.


name: ACPM_HUMAN Acyl carrier protein, mitochondrial (sprot)

description: An acyl carrier protein, mitochondrial that is encoded in the genome of human.


acetamide

A member of the class of acetamides that results from the formal condensation of acetic acid with ammonia.


S10A2_HUMAN Protein S100-A2 (sprot)

A protein S100-A2 that is encoded in the genome of human.


potassium iodide

A metal iodide salt with a K(+) counterion. It is a scavenger of hydroxyl radicals.


name: MAML2_HUMAN Mastermind-like protein 2 (sprot)

description: A mastermind-like protein 2 that is encoded in the genome of human.


An optically active form of 4-hydroxyproline having L-trans-configuration.


myasthenia gravis

description: Myasthenia gravis (MG) is a rare, clinically heterogeneous, autoimmune disorder of the neuromuscular junction characterized by fatigable weakness of voluntary muscles.


dexketoprofen

A monocarboxylic acid that is (S)-hydratropic acid substituted at position 3 on the phenyl ring by a benzoyl group. A cyclooxygenase inhibitor, it is used to relieve short-term pain, such as muscular pain, dental pain and dysmenorrhoea.


name: HCN4_HUMAN Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (sprot)

description: A potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 that is encoded in the genome of human.


name: PERP_HUMAN p53 apoptosis effector related to PMP-22 (sprot)

description: A p53 apoptosis effector related to PMP-22 that is encoded in the genome of human.


name: KTAP2_HUMAN Keratinocyte-associated protein 2 (sprot)

description: A keratinocyte-associated protein 2 that is encoded in the genome of human.


SYRINGIC ACID

A dimethoxybenzene that is 3,5-dimethyl ether derivative of gallic acid.


skin papilloma

description: A benign papillary neoplastic growth on the skin composed of epithelial cells and a fibrous stalk. It usually develops in the eyelid, axilla, neck, upper chest, and groin.


sphingosine 1-phosphate

A phosphosphingolipid that consists of sphingosine having a phospho group attached at position 1


name: ABCC8_HUMAN ATP-binding cassette sub-family C member 8 (sprot)

description: An ATP-binding cassette sub-family C member 8 that is encoded in the genome of human.


name: SOCS6_HUMAN Suppressor of cytokine signaling 6 (sprot)

description: A suppressor of cytokine signaling 6 that is encoded in the genome of human.


name: TMX1_HUMAN Thioredoxin-related transmembrane protein 1 (sprot)

description: A thioredoxin-related transmembrane protein 1 that is encoded in the genome of human.


name: AA3R_HUMAN Adenosine receptor A3 (sprot)

description: An adenosine receptor A3 that is encoded in the genome of human.


leukoplakia

description: A white patch or plaque on a mucous membrane that cannot be characterized clinically or pathologically as any other disease. The diagnosis of leukoplakia is one of exclusion; other conditions such as candidiasis, lichen planus, leukoedema, etc., must be ruled out before a diagnosis of leukoplakia can be made. Leukoplakia may be a premalignant condition.


name: IKBA_HUMAN NF-kappa-B inhibitor alpha (sprot)

description: An NF-kappa-B inhibitor alpha that is encoded in the genome of human.


name: WSB1_HUMAN WD repeat and SOCS box-containing protein 1 (sprot)

description: A WD repeat and SOCS box-containing protein 1 that is encoded in the genome of human.


name: MMP28_HUMAN Matrix metalloproteinase-28 (sprot)

description: A matrix metalloproteinase-28 that is encoded in the genome of human.


name: RGRF1_HUMAN Ras-specific guanine nucleotide-releasing factor 1 (sprot)

description: A Ras-specific guanine nucleotide-releasing factor 1 that is encoded in the genome of human.


LYAM3_HUMAN P-selectin (sprot)

A P-selectin that is encoded in the genome of human.


A member of the class of quinolines that is 7-methoxyquinoline substituted at position 4 by a (6-phenyl[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methoxy group. AMG exhibits antitumour activity, particularly in prostate cancer.


tobramycin

A amino cyclitol glycoside that is kanamycin B lacking the 3-hydroxy substituent from the 2,6-diaminoglucose ring.


WNT2_HUMAN Protein Wnt-2 (sprot)

A protein Wnt-2 that is encoded in the genome of human.


hypoparathyroidism

description: Hypoparathyroidism is an endocrine disorder in which the parathyroid glands in the neck do not produce enough parathyroid hormone (PTH). Common signs and symptoms include abdominal pain, brittle nails, cataracts, dry hair and skin, muscle cramps, tetany, pain in the face, legs, and feet, seizures, tingling sensation, and weakened tooth enamel (in children). It may be caused by injury to the parathyroid glands (e.g., during surgery). Other causes, include low blood magnesium levels, a side effect of radioactive iodine treatment for hyperthyroidism, metabolic alkalosis, DiGeorge syndrome, and type I polyglandular autoimmune syndrome. The goal of treatment is to restore the calcium and mineral balance in the body.


name: CARM1_HUMAN Histone-arginine methyltransferase CARM1 (sprot)

description: A histone-arginine methyltransferase CARM1 that is encoded in the genome of human.


griseofulvin

An oxaspiro compound produced by Penicillium griseofulvum. It is used by mouth as an antifungal drug for infections involving the scalp, hair, nails and skin that do not respond to topical treatment.


CDC73_HUMAN Parafibromin (sprot)

A parafibromin that is encoded in the genome of human.


Recurrent bacterial infections

description: Increased susceptibility to bacterial infections, as manifested by recurrent episodes of bacterial infection.


name: TRXR1_HUMAN Thioredoxin reductase 1, cytoplasmic (sprot)

description: A thioredoxin reductase 1, cytoplasmic that is encoded in the genome of human.


name: SRSF2_HUMAN Serine/arginine-rich splicing factor 2 (sprot)

description: A splicing factor, arginine/serine-rich 2 that is encoded in the genome of human.


SDMA

A  L-arginine derivative having two methyl groups at the N(omega)- and N'(omega)-positions


name: CSAG2_HUMAN Chondrosarcoma-associated gene 2/3 protein (sprot)

description: A chondrosarcoma-associated gene 2/3A protein that is encoded in the genome of human.


name: TAF4_HUMAN Transcription initiation factor TFIID subunit 4 (sprot)

description: A transcription initiation factor TFIID subunit 4 that is encoded in the genome of human.


name: INAR1_HUMAN Interferon alpha/beta receptor 1 (sprot)

description: An interferon-alpha/beta receptor alpha chain that is encoded in the genome of human.


latanoprost (isopropyl ester)

A prostaglandin Falpha that is the isopropyl ester prodrug of latanoprost free acid. Used in the treatment of open-angle glaucoma and ocular hypertension.


name: MIC25_HUMAN MICOS complex subunit MIC25 (sprot)

description: A MICOS complex subunit MIC25 that is encoded in the genome of human.


name: MIC60_HUMAN MICOS complex subunit MIC60 (sprot)

description: A MICOS complex subunit MIC60 that is encoded in the genome of human.


name: TBX20_HUMAN T-box transcription factor TBX20 (sprot)

description: A T-box transcription factor TBX20 that is encoded in the genome of human.


NXP20_HUMAN Protein NOXP20 (sprot)

A protein NOXP20 that is encoded in the genome of human.


L-α-methyldopa

A derivative of L-tyrosine having a methyl group at the alpha-position and an additional hydroxy group at the 3-position on the phenyl ring.


orthostatic hypotension

description: Sudden fall of the blood pressure of at least 20/10 mm Hg when a person stands up.


WNT4_HUMAN Protein Wnt-4 (sprot)

A protein Wnt-4 that is encoded in the genome of human.


name: LECT2_HUMAN Leukocyte cell-derived chemotaxin-2 (sprot)

description: A leukocyte cell-derived chemotaxin-2 that is encoded in the genome of human.


LEUPEPTIN

A tripeptide composed of N-acetylleucyl, leucyl and argininal residues joined in sequenceby peptide linkages. It is an inhibitor of the calpains, a family of calcium-activated proteases which promote cell death.


KLK11_HUMAN Kallikrein-11 (sprot)

A kallikrein-11 that is encoded in the genome of human.


name: GNL3_HUMAN Guanine nucleotide-binding protein-like 3 (sprot)

description: A guanine nucleotide-binding protein-like 3 that is encoded in the genome of human.


stavudine

A nucleoside analogue obtained by formal dehydration across positions 2 and 3 of thymidine. An inhibitor of HIV-1 reverse transcriptase


name: RELB_HUMAN Transcription factor RelB (sprot)

description: A transcription factor RelB that is encoded in the genome of human.


Enlarged tonsils

description: Increase in size of the tonsils, small collections of lymphoid tissue facing into the aerodigestive tract on either side of the back part of the throat.


CP2C9_HUMAN Cytochrome P450 2C9 (sprot)

A cytochrome P450 2C9 that is encoded in the genome of human.


sulindac

A monocarboxylic acid that is 1-benzylidene-1H-indene which is substituted at positions 2, 3, and 5 by methyl, carboxymethyl, and fluorine respectively, and in which the phenyl group of the benzylidene moiety is substituted at the para position by a methylsulfinyl group. It is a prodrug for the corresponding sulfide, a non-steroidal anti-inflammatory drug, used particularly in the treatment of acute and chronic inflammatory conditions.


trientine

A polyazaalkane that is decane in which the carbon atoms at positions 1, 4, 7 and 10 are replaced by nitrogens.


name: IF2P_HUMAN Eukaryotic translation initiation factor 5B (sprot)

description: A eukaryotic translation initiation factor 5B that is encoded in the genome of human.


meclofenamic acid

An aminobenzoic acid that is anthranilic acid in which one of the hydrogens attached to the nitrogen is replaced by a 2,6-dichloro-3-methylphenyl group. A non-steroidal anti-inflammatory drug, it is used as the sodium salt for the treatment of dysmenorrhoea (painful periods), osteoarthritis and rheumatoid arthritis.


NPNT_HUMAN Nephronectin (sprot)

A nephronectin that is encoded in the genome of human.


name: CNKR3_HUMAN Connector enhancer of kinase suppressor of ras 3 (sprot)

description: A connector enhancer of kinase suppressor of ras 3 that is encoded in the genome of human.


LCAT deficiency

description: LCAT (lecithin-cholesterol acyltransferase) deficiency is a rare lipoprotein metabolism disorder characterized clinically by corneal opacities, and sometimes renal failure and hemolytic anemia, and biochemically by severely reduced HDL cholesterol.


polymorphic ventricular tachycardia

description: A ventricular tachycardia that is irregular in rate and rhythm.


name: NUF2_HUMAN Kinetochore protein Nuf2 (sprot)

description: A kinetochore protein Nuf2 that is encoded in the genome of human.


name: SPRE1_HUMAN Sprouty-related, EVH1 domain-containing protein 1 (sprot)

description: A sprouty-related, EVH1 domain-containing protein 1 that is encoded in the genome of human.


DBNL_HUMAN Drebrin-like protein (sprot)

A drebrin-like protein that is encoded in the genome of human.