name: Stage IB Mycosis Fungoides and Sezary Syndrome AJCC v8

description: Stage IB includes: T2, N0, M0, B0,1. T2: Patches, papules, or plaques covering 10% or more of the skin surface. N0: No clinically abnormal peripheral lymph nodes; biopsy not required. M0: No visceral organ involvement. B0: Absence of significant blood involvement: 5% or less of peripheral blood lymphocytes are atypical (Sezary cells). B1: Low blood tumor burden: more than 5% of peripheral blood lymphocytes are atypical (Sezary cells) but does not meet the criteria of B2. (AJCC 8th ed.)


name: Ann Arbor Stage IV Mature T- and NK-Cell Lymphoma

category: biolink:Disease biolink:DiseaseOrPhenotypicFeature biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing

description: Ann Arbor Classification: Stage IV: Diffuse or disseminated involvement of one or more extralymphatic organs, with or without associated lymph node involvement; or isolated extralymphatic organ involvement in the absence of adjacent regional lymph node involvement, but in conjunction with disease in distant site(s); or any involvement of the liver or bone marrow, lungs (other than by direct extension from another site), or cerebrospinal fluid.


Mycosis fungoides refractory

description: Mycosis fungoides resistant to treatment.


name: Stage IIB Mycosis Fungoides and Sezary Syndrome AJCC v7

description: Stage IIB includes: T3, N0-2, M0, B0-1.  T3: One or more tumors (equal or greater than 1 cm diameter).  N0: No clinically abnormal peripheral lymph nodes; biopsy not required.  N1: Clinically abnormal peripheral lymph nodes; histopathology Dutch grade 1 or NCI LN0-2.  N2: Clinically abnormal peripheral lymph nodes; histopathology Dutch grade 2 or NCI LN3.  M0: No visceral organ involvement.  B0: Absence of significant blood involvement: 5% or less of peripheral blood lymphocytes are atypical (Sezary cells).  B1: Low blood tumor burden: more than 5% of peripheral blood lymphocytes are atypical (Sezary cells) but does not meet the criteria of B2.  (AJCC 7th ed.)


name: Systemic Anaplastic Large Cell Lymphoma, ALK-Positive

description: A T-cell peripheral lymphoma affecting multiple anatomic sites. It is composed of usually large, pleomorphic, CD30 positive T-lymphocytes with abundant cytoplasm. It is characterized by the presence of a translocation involving the ALK gene and expression of ALK fusion protein.


Follicular Helper T-Cell Lymphoma

description: A group of node-based peripheral T-cell lymphomas with phenotypic features of T follicular helper (TFH) cells. This category includes the following: follicular helper T-cell lymphoma, angioimmunoblastic-type; follicular helper T-cell lymphoma, follicular-type; and follicular helper T-cell lymphoma, not otherwise specified.


name: Recurrent Follicular Helper T-Cell Lymphoma

description: The reemergence of follicular helper T-cell lymphoma after a period of remission.


splenic mantle cell lymphoma

description: A mantle cell lymphoma occurring in the spleen.


name: Recurrent Transformed Marginal Zone Lymphoma to Diffuse Large B-Cell Lymphoma

description: The reemergence of diffuse large B-cell lymphoma that resulted from the transformation of marginal zone lymphoma, after a period of remission.


Recurrent Burkitt Lymphoma

description: The reemergence of Burkitt lymphoma after a period of remission.


Prostate Diffuse Large B-Cell Lymphoma

description: A rare diffuse large B-cell lymphoma that arises from the prostate gland.


name: Monomorphic epitheliotropic intestinal T-cell lymphoma

description: A mature T-cell and NK-cell non-Hodgkin lymphoma of intraepithelial T-lymphocytes. It usually arises from the small intestine. A minority of cases arise from the large intestine or the stomach. It is characterized by the presence of a monomorphic cellular infiltrate of small to medium-sized T-lymphocytes that are cytotoxic and express CD56. It is not associated with celiac disease.


name: large B-cell diffuse lymphoma of salivary gland

description: A diffuse large B-cell lymphoma that manifests initially in a salivary gland. It usually occurs in the parotid gland.


name: Ann Arbor Stage II Grade 1 Follicular Lymphoma

description: Ann Arbor Classification: Stage II: Involvement of two or more lymph node regions on the same side of the diaphragm (II); or localized involvement of a single extralymphatic organ or site in association with regional lymph node involvement with or without involvement of other lymph node regions on the same side of the diaphragm (IIE).


name: Childhood Anaplastic Large Cell Lymphoma

description: An anaplastic large cell lymphoma that occurs during childhood.


name: Anaplastic Lymphoma Post-Transplant Lymphoproliferative Disorder

description: An anaplastic lymphoma that arises in a patient with a history of organ transplantation.


name: Stage IV Indolent Adult Non-Hodgkin Lymphoma


name: Ann Arbor Stage III Grade 3 Follicular Lymphoma

description: Ann Arbor Classification: Stage III: Involvement of lymph node regions on both sides of the diaphragm (III), which also may be accompanied by extralymphatic extension in association with adjacent lymph node involvement (IIIE) or by involvement of the spleen (IIIS) or both (IIIE,S).


T-cell lymphoma stage II

description: Ann Arbor Classification: Stage II: Involvement of two or more lymph node regions on the same side of the diaphragm (II); or localized involvement of a single extralymphatic organ or site in association with regional lymph node involvement with or without involvement of other lymph node regions on the same side of the diaphragm (IIE). The number of regions involved may be indicated by a subscript (e.g., II3).


name: Refractory Primary Cutaneous Anaplastic Large Cell Lymphoma

description: Primary cutaneous anaplastic large cell lymphoma that is resistant to treatment.


Sezary syndrome refractory

description: Sezary syndrome that is resistant to treatment.


follicular lymphoma of spleen

description: A follicular lymphoma occurring in the spleen.


name: Refractory Transformed Follicular Lymphoma to Diffuse Large B-Cell Lymphoma

description: Transformed follicular lymphoma to diffuse large B-cell lymphoma that is resistant to treatment.


name: central nervous system anaplastic large cell lymphoma

description: An anaplastic large cell lymphoma that affects the brain, meninges, or spinal cord.


name: Ann Arbor Stage II Grade 1 Contiguous Follicular Lymphoma


name: Lacrimal Gland Mucosa-Associated Lymphoid Tissue Lymphoma

description: A mucosa-associated lymphoid tissue lymphoma that arises from the lacrimal gland.


name: Hodgkin-Like Adult T-Cell Leukemia/Lymphoma

description: A rare morphologic variant of adult T-cell leukemia/lymphoma characterized by the presence of Hodgkin-like and Reed-Sternberg-like cells.


name: Follicular Helper T-Cell Lymphoma, Angioimmunoblastic-Type by Ann Arbor Stage

description: An anatomic stage for follicular helper T-cell lymphoma, angioimmunoblastic-type  based on the Ann Arbor classification criteria.


Triple hit lymphoma

description: High-grade B-cell lymphoma characterized by the abnormal rearrangement of MYC gene, BCL2 gene, and BCL6 gene. Patients with this type of lymphoma usually respond poorly to standard treatments and have a poor prognosis.


description: Waldenstrom macroglobulinemia that does not respond to treatment.


name: Ann Arbor Stage III Aggressive Adult Non-Hodgkin Lymphoma


Blastoid Variant Mantle Cell Lymphoma

description: An aggressive mantle cell lymphoma characterized by the presence of neoplastic B-lymphocytes resembling lymphoblasts.


name: Ann Arbor Stage I Grade 2 Follicular Lymphoma

description: Ann Arbor Classification: Stage I: Involvement of a single lymph node region (I); or localized involvement of a single extralymphatic organ or site in the absence of any lymph node involvement (IE).


name: Precursor B-lymphoblastic lymphoma stage III


name: BCL2-R-Negative, CD23-Positive Follicle Center Lymphoma

description: Follicular lymphoma characterized by the absence of BCL2 rearrangement and the presence of CD23-positive neoplastic cells. It is associated with STAT6 mutations. It presents with low-stage disease, typically in the inguinal region, and often has a predominant diffuse growth pattern.


name: Ann Arbor Stage II Grade 2 Contiguous Follicular Lymphoma

description: Ann Arbor Classification: Stage II: Involvement of two or more lymph node regions on the same side of the diaphragm (II); or localized involvement of a single extralymphatic organ or site in association with regional lymph node involvement with or without involvement of other lymph node regions on the same side of the diaphragm (IIE).


localized pagetoid reticulosis

description: A variant of mycosis fungoides, characterized by an exclusively intraepidermal atypical (cerebriform) lymphocytic infiltrate. Patients present with a localized psoriasiform or hyperkeratotic patch or plaque, usually in the extremities. Extracutaneous dissemination of the disease has never been reported.


name: Refractory Systemic Anaplastic Large Cell Lymphoma

description: Systemic anaplastic large cell lymphoma that does not respond to treatment.


name: Primary Vitreoretinal Non-Hodgkin Lymphoma

description: An uncommon and potentially fatal intraocular non-Hodgkin lymphoma that involves the uvea, retina, vitreous body, and optic nerve. It is a subset of primary central nervous system non-Hodgkin lymphoma. The majority of cases are diffuse large B-cell lymphomas.


grade 3B follicular lymphoma

description: A grade 3 follicular lymphoma composed of solid sheets of centroblasts.


Recurrent Hepatosplenic T-Cell Lymphoma

description: The reemergence of hepatosplenic T-cell lymphoma after a period of remission.


Grade III Lymphomatoid Granulomatosis

description: Lymphomatoid granulomatosis characterized by the presence of aggregates of neoplastic large B-lymphocytes, usually admixed with pleomorphic and Hodgkin-like cells, in a background of chronic inflammation.  Necrotic changes are present and are usually extensive.  Grade III lymphomatoid granulomatosis should be approached clinically as a subtype of diffuse large B-cell lymphoma.


name: Adult Systemic Anaplastic Large Cell Lymphoma

description: An anaplastic large cell lymphoma affecting multiple anatomic sites and occurring in adults.


name: Predominantly Diffuse Follicular Lymphoma with 1p36 Deletion

description: A predominantly diffuse, low-grade follicular lymphoma. It often presents as a large localized inguinal mass, lacks BCL2 rearrangement, and is associated with 1p36 deletion.


Colon Diffuse Large B-Cell Lymphoma

description: A diffuse large B-cell lymphoma that arises from the colon.  It is the most frequent type of lymphoma found in the colon.


Mycosis fungoides stage I

description: Stage I includes: IA (T1, N0, M0, B0-1); IB (T2, N0, M0, B0-1). T1: Limited patches, papules, and/or plaques covering less than 10% of the skin surface.  May further stratify into T1a (patch only) vs. T1b (plaque +/- patch).  T2: Patches, papules, or plaques covering 10% or more of the skin surface.  May further stratify into T2a (patch only) vs. T2b (plaque +/- patch).  N0: No clinically abnormal peripheral lymph nodes; biopsy not required.  M0: No visceral organ involvement.  B0: Absence of significant blood involvement: 5% or less of peripheral blood lymphocytes are atypical (Sezary cells).  B1: Low blood tumor burden: more than 5% of peripheral blood lymphocytes are atypical (Sezary cells) but does not meet the criteria of B2.  (AJCC 7th ed.)


name: Stage III Childhood Anaplastic Large Cell Lymphoma

description: Ann Arbor Classification: Stage III: Involvement of lymph node regions on both sides of the diaphragm (III), which also may be accompanied by extralymphatic extension in association with adjacent lymph node involvement (IIIE) or by involvement of the spleen (IIIS) or both (IIIE,S).


name: Nodal marginal zone B-cell lymphoma stage II


Childhood Immunoblastic Lymphoma

description: An immunoblastic lymphoma (a variant of diffuse large B-cell lymphoma) occurring in children.


Prostate Mantle Cell Lymphoma

description: A rare mantle cell lymphoma that arises from the prostate gland.


description: The reemergence of lymphoplasmacytic lymphoma after a period of remission.


name: Refractory Transformed T-cell Non-Hodgkin Lymphoma

description: An indolent T-cell non-Hodgkin lymphoma which has undergone histologic transformation to an aggressive T-cell non-Hodgkin lymphoma and has become resistant to treatment.


Non-Hodgkin Lymphoma by Ann Arbor Stage

description: An anatomic stage for non-Hodgkin lymphomas based on the Ann Arbor classification criteria.


name: Stage IVB Mycosis Fungoides and Sezary Syndrome AJCC v7

description: Stage IVB includes: T1-4, N0-3, M1, B0-2. T1: Limited patches, papules, and/or plaques covering less than 10% of the skin surface.  May further stratify into T1a (patch only) vs. T1b (plaque +/- patch).  T2: Patches, papules, or plaques covering 10% or more of the skin surface.  May further stratify into T2a (patch only) vs. T2b (plaque +/- patch).  T3: One or more tumors (equal or greater than 1 cm diameter).  T4: Confluence of erythema covering 80% or more of body surface area.  N0: No clinically abnormal peripheral lymph nodes; biopsy not required.  N1: Clinically abnormal peripheral lymph nodes; histopathology Dutch grade 1 or NCI LN0-2.  N2: Clinically abnormal peripheral lymph nodes; histopathology Dutch grade 2 or NCI LN3.  N3: Clinically abnormal peripheral lymph nodes; histopathology Dutch grades 3-4 or NCI LN4; clone positive or negative.  M1: Visceral involvement (must have pathology confirmation and organ involved should be specified).  B0: Absence of significant blood involvement: 5% or less of peripheral blood lymphocytes are atypical (Sezary cells).  B1: Low blood tumor burden: more than 5% of peripheral blood lymphocytes are atypical (Sezary cells) but does not meet the criteria of B2.  B2: High blood tumor burden: 1000/microL Sezary cells or more with positive clone.  (AJCC 7th ed.)


name: Lymphoplasmacytoid lymphoma/immunocytoma stage III


name: Refractory Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma

description: Mature T-cell and NK-cell non-Hodgkin lymphoma that is resistant to treatment.


name: AIDS-Related Non-Hodgkin Lymphoma of the Cervix

description: A non-Hodgkin lymphoma that arises from the cervix in a patient with acquired immunodeficiency syndrome.


name: Liver Mucosa-Associated Lymphoid Tissue Lymphoma

description: A rare mucosa-associated lymphoid tissue lymphoma that arises from the liver.  It is characterized by the presence of centrocyte-like cells surrounding germinal centers.  Lymphoepithelial lesions involving the bile duct epithelium may also be present.


Cyclin D1-Positive Mantle Cell Lymphoma

description: A molecular subtype of mantle cell lymphoma characterized by the presence of cyclin D1 expression and/or CCND1 rearrangement..


Mature B-Cell Non-Hodgkin Lymphoma

description: A non-Hodgkin lymphoma that originates from mature B lymphocytes. Representative examples include diffuse large B-cell lymphoma, follicular lymphoma, marginal zone lymphoma, mantle cell lymphoma, and small lymphocytic lymphoma.


name: small cell variant anaplastic large cell lymphoma

description: A histologic variant of anaplastic large cell lymphoma characterized by the presence of a predominant population of small to medium size malignant cells with irregular nuclei.


name: Ann Arbor Stage II Non-Contiguous Mantle Cell Lymphoma

description: Stage II: Involvement of two or more lymph node regions on the same side of the diaphragm (II) or localized involvement of a single associated extralymphatic organ or site and its regional lymph nodes with or without other lymph node regions on the same side of the diaphragm (IIE). Note: The number of lymph node regions involved may be indicated by a subscript (e.g., II3). (from PDQ)


name: Ann Arbor Stage I Aggressive Adult Non-Hodgkin Lymphoma

description: Ann Arbor Classification: Stage I: Involvement of a single lymph node region (I); or localized involvement of a single extralymphatic organ or site in the absence of any lymph node involvement (IE).


Refractory Gray-Zone Lymphoma

description: Gray-zone lymphoma that is resistant to treatment.


name: Anaplastic large cell lymphoma T- and null-cell types refractory

description: Anaplastic large cell lymphoma resistant to treatment.


Mediastinal Non-Hodgkin Lymphoma

description: Non-Hodgkin lymphoma arising from the mediastinum.


name: Chlamydia Psittaci-Associated Ocular Adnexal Mucosa-Associated Lymphoid Tissue Lymphoma

description: Mucosa-associated lymphoid tissue lymphoma that arises from the ocular adnexa and caused by stimulation of lymphoid tissue due to Chlamydia psittaci bacterial infection.


Colorectal Burkitt Lymphoma

description: A rare Burkitt lymphoma that arises from the colon or rectum.


name: Recurrent Systemic Anaplastic Large Cell Lymphoma

description: The reemergence of systemic anaplastic large cell lymphoma after a period of remission.


Stage IV Diffuse Large B-Cell Lymphoma

description: Ann Arbor Classification: Stage IV: Diffuse or disseminated involvement of one or more extralymphatic organs, with or without associated lymph node involvement; or isolated extralymphatic organ involvement in the absence of adjacent regional lymph node involvement, but in conjunction with disease in distant site(s); or any involvement of the liver or bone marrow, lungs (other than by direct extension from another site), or cerebrospinal fluid.


Colon Mantle Cell Lymphoma

description: A mantle cell lymphoma that arises from the colon.  It often presents as a polypoid lesion.


name: Smoldering Adult T-Cell Leukemia/Lymphoma

description: An adult T-cell leukemia/lymphoma characterized by less than 5% neoplastic lymphocytes in the peripheral blood, absence of lymphadenopathy and hypercalcemia, and occasional skin or pulmonary lesions.


follicular malignant lymphoma of breast

description: A follicular lymphoma that arises from the breast as a primary tumor.


name: ankyrin repeat and SOCS box protein 16 isoform 1 (human)

description: An ankyrin repeat and SOCS box protein 16 isoform 1 that is encoded in the genome of human.


name: cyclin-dependent kinase inhibitor 1C isoform Long (human)

description: A cyclin-dependent kinase inhibitor 1C (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P49918-1.


name: cyclin-dependent kinase inhibitor 1C phosphorylated 1 (human)

description: A cyclin-dependent kinase inhibitor 1C (human) that has been phosphorylated on the residue at the position equivalent to Tyr-91 of the amino acid sequence represented by UniProtKB:P49918-1. Example: UniProtKB:P49918-1, Tyr-91, MOD:00048.


name: cyclin-dependent kinase inhibitor 1C isoform Short (human)

description: A cyclin-dependent kinase inhibitor 1C (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P49918-2.


name: Charcot-Marie-Tooth disease X-linked recessive 3

description: X-linked Charcot-Marie-Tooth disease type 3 is a rare, genetic, peripheral sensorimotor neuropathy characterized by an X-linked recessive inheritance pattern and the childhood- to adolescent-onset of progressive, distal muscle weakness and atrophy (beginning in the lower extremities and then affecting the upper extremities), as well as distal, pansensory loss in the upper and lower extremities, pes cavus, and absent or reduced distal tendon reflexes. Pain and paresthesia are frequently the initial sensory symptoms. Spastic paraparesis (manifested by clasp-knife sign, hyperactive deep-tendon reflexes, and Babinski sign) has also been reported.


Charcot-Marie-Tooth disease type X

description: A subtype of Charcot-Marie-Tooth disease with genetic defects on the X chromosome.


name: Charcot-Marie-Tooth disease X-linked recessive 4

description: X-linked Charcot-Marie-Tooth disease type 4 is a rare, genetic, axonal, peripheral sensorimotor neuropathy characterized by an X-linked recessive inheritance pattern and the neonatal- to early childhood-onset of severe, slowly progressive, distal muscle weakness and atrophy (in particular of the peroneal group), as well as sensory impairment (with the lower extremities being more affected than the upper extremities), pes cavus, areflexia and hammertoes. Sensorineural hearing loss and cognitive impairment may also be associated. Females are asymptomatic and do not display the phenotype.


name: Charcot-Marie-Tooth disease X-linked recessive 5

description: X-linked Charcot-Marie-Tooth disease type 5 is a rare, genetic, peripheral sensorimotor neuropathy characterized by an X-linked recessive inheritance pattern and the infancy- to childhood-onset of: 1) progressive distal muscle weakness and atrophy (first appearing and more prominent in the lower extremities than the upper) which usually manifests with foot drop and gait disturbance, 2) bilateral, profound, prelingual sensorineural hearing loss and 3) progressive optic neuropathy. Females are asymptomatic and do not display the phenotype.


name: Charcot-Marie-Tooth disease X-linked dominant 1

description: Charcot-Marie-Tooth neuropathy that is inherited in an X-linked manner, and is associated with mutation(s) in the GJB1 gene, encoding gap junction beta-1 protein. The condition is characterized by moderate to severe motor and sensory neuropathy in males, and mild to no symptoms in females.


name: Charcot-Marie-Tooth disease X-linked recessive 2

description: X-linked Charcot-Marie-Tooth disease type 2 is a rare, genetic, peripheral sensorimotor neuropathy characterized by an X-linked recessive inheritance pattern and the infantile- to childhood-onset of progressive, distal muscle weakness and atrophy (more prominent in the lower extremities than in the upper extremities), pes cavus, and absent tendon reflexes. Sensory impairment and intellectual disability has been reported in some individuals.


name: Charcot-Marie-Tooth disease X-linked dominant 6

description: X-linked Charcot-Marie-Tooth disease type 6 is a rare, genetic, principally axonal, peripheral sensorimotor neuropathy characterized by an X-linked dominant inheritance pattern and the childhood-onset of slowly progressive, moderate to severe, distal muscle weakness and atrophy of the lower extremities, as well as distal, panmodal sensory abnormalities, bilateral foot deformities (pes cavus, clawed toes), absent ankle reflexes and gait abnormalities (steppage gait). Females are usually asymptomatic or only present mild manifestations (mild postural hand tremor, mild wasting of hand intrinsic muscles).


N(1)-methyladenosine 5'-monophosphate

A purine ribonucleoside 5'-monophosphate that is AMP monomethylated on N(1).


statin (semi-synthetic)

A statin that is derived from a naturally occurring statin by partial chemical synthesis.


name: eukaryotic translation initiation factor 4E-binding protein 1 isoform 1 phosphorylated 1 (human)

description: A eukaryotic translation initiation factor 4E-binding protein 1 isoform 1 phosphorylated 1 in human. UniProtKB:Q13541-1, 2-118, Thr-37/Thr-46, MOD:00047.


name: eukaryotic translation initiation factor 4E-binding protein 1 isoform 1 (human)

description: A eukaryotic translation initiation factor 4E-binding protein 1 isoform 1 that is encoded in the genome of human.


hippocampal sclerosis of aging

description: Age-related neuropathological condition with severe neuronal cell loss and gliosis in the hippocampus


prosaposin N-glycosylated 94 (human)

A prosaposin (human) that has been N-glycosylated at the residue equivalent to Asn-80 of the amino acid sequence represented by UniProtKB:P07602-1, in which the glycan structure is represented by GlyTouCan:G82348BZ. Example: UniProtKB:P07602-1, Asn-80, MOD:00160~GNO:G82348BZ.


name: transcription initiation factor TFIID subunit 8 isoform h1 (human)

description: A transcription initiation factor TFIID subunit 8 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q7Z7C8-1.


name: kinesin-like protein KIF3B deaminated 1 (human)

description: A kinesin-like protein KIF3B (human) that has been deaminated on the residue at the position equivalent to Asn-323 of the amino acid sequence represented by UniProtKB:O15066-1. Example: UniProtKB:O15066-1, Asn-323, MOD:00684.


name: kinesin-like protein KIF3B isoform 1 (human)

description: A kinesin-like protein KIF3B isoform 1 that is encoded in the genome of human.


name: kinesin-like protein KIF3B isoform h2 (human)

description: A kinesin-like protein KIF3B (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O15066-2.


Benign cyst of ovary

description: A non-malignant ovarian cyst.


corpus luteum cyst

description: A ovarian cyst (disease) that involves the corpus luteum.


name: Large Solitary Luteinized Follicle Cyst of Ovary

description: A large, unilateral, solitary ovarian cyst lined by luteinized cells, occurring during pregnancy or puerperium. (WHO 2020)


Complex ovarian cyst

description: A cystic lesion that arises from the ovary. It is characterized by the presence of cystic spaces that contain fluid and a solid tissue component.


Unilocular Ovarian Cyst

category: biolink:PhenotypicFeature biolink:DiseaseOrPhenotypicFeature biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing

description: An ovarian cyst that has a single compartment.


Follicular cyst of ovary

description: A benign ovarian cyst that develops from a persistent, unruptured Graafian follicle, which grows larger than three centimeters.


Autonomous Ovarian Follicular Cyst

description: A cyst arising from an ovarian follicle that produces hormones independent of gonadotropin stimulation.


Functional cyst of ovary

description: A benign ovarian cyst that develops and regresses during the menstrual cycle as part of normal ovarian function.


name: sorbin and SH3 domain-containing protein 2 isoform h11 (human)

description: A sorbin and SH3 domain-containing protein 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O94875-11.


name: saturated organic heteromonocyclic parent


dioxane

Any member of the class of dioxanes that is a cyclohexane in which two carbon atoms are replaced by oxygen atoms.


dithianes

An organosulfur heterocyclic compound containing a six-member aliphatic saturated heterocycle made up of two sulfur atoms and four carbon atoms.


name: extracellular serine/threonine protein kinase FAM20C isoform h1 (human)

description: An extracellular serine/threonine protein kinase FAM20C (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8IXL6-1.


name: complement factor H N-glycosylated 52 (human)

description: A complement factor H (human) that has been N-glycosylated at the residue equivalent to Asn-911 of the amino acid sequence represented by UniProtKB:P08603-1, in which the glycan structure is represented by GlyTouCan:G42358LZ. Example: UniProtKB:P08603-1, Asn-911, MOD:00160~GNO:G42358LZ.


name: guanine nucleotide exchange protein SMCR8

description: A protein that is a translation product of the human SMCR8 gene or a 1:1 ortholog thereof.


name: guanine nucleotide exchange protein SMCR8 isoform h1 (human)

description: A guanine nucleotide exchange protein SMCR8 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8TEV9-1.


name: guanine nucleotide exchange protein SMCR8 methylated 1 (human)

description: A guanine nucleotide exchange protein SMCR8 (human) that has been methylated on the residue at the position equivalent to Cys-350 of the amino acid sequence represented by UniProtKB:Q8TEV9-1. Example: UniProtKB:Q8TEV9-1, Cys-350, MOD:00660.


name: guanine nucleotide exchange protein SMCR8 isoform h2 (human)

description: A guanine nucleotide exchange protein SMCR8 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8TEV9-2.


name: microfibrillar-associated protein 3-like phosphorylated 1 (human)

description: A microfibrillar-associated protein 3-like (human) that has been phosphorylated on the residue at the position equivalent to Tyr-287 of the amino acid sequence represented by UniProtKB:O75121-1. Example: UniProtKB:O75121-1, Tyr-287, MOD:00048.


name: microfibrillar-associated protein 3-like isoform h3 (human)

description: A microfibrillar-associated protein 3-like (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O75121-3.


name: microfibrillar-associated protein 3-like isoform h2 (human)

description: A microfibrillar-associated protein 3-like (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O75121-2.


name: microfibrillar-associated protein 3-like isoform 1 (human)

description: A microfibrillar-associated protein 3-like isoform 1 that is encoded in the genome of human.


name: alpha-endosulfine, initiator methionine removed phosphorylated 2 (human)

description: An alpha-endosulfine (human) that has had the initiator methionine removed and has been post-translationally modified to include phosphoserine at position 67 of the amino acid sequence represented by UniProtKB:O43768. UniProtKB:O43768, 2-121, Ser-67, MOD:00046.


A contactin that is a translation product of the human CNTN3 gene or a 1:1 ortholog thereof.


contactin-3 isoform 1 (human)

A contactin-3 isoform 1 that is encoded in the genome of human.


contactin-3 citrullinated 1 (human)

A contactin-3 (human) that has been citrullinated on the residue at the position equivalent to Arg-565 of the amino acid sequence represented by UniProtKB:Q9P232. UniProtKB:Q9P232, Arg-565, MOD:00219.


complement C4-A deaminated 5 (human)

A complement C4-A (human) that has been deaminated on the residue at the position equivalent to Asn-1347 of the amino acid sequence represented by UniProtKB:P0C0L4-1. Example: UniProtKB:P0C0L4-1, Asn-1347, MOD:00684.


5beta-Cholestane-3alpha,7alpha,24,26-tetrol with S-configuration at C-24.


The bromide salt of 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium.


name: phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha deaminated 1 (human)

description: A phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha (human) that has been deaminated on the residue at the position equivalent to Gln-1054 of the amino acid sequence represented by UniProtKB:O00443-1. Example: UniProtKB:O00443-1, Gln-1054, MOD:00685.


name: phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha

description: A protein that is a translation product of the human PIK3C2A gene or a 1:1 ortholog thereof.


name: phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha isoform h2 (human)

description: A phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O00443-2.


name: phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha, initiator methionine removed form (human)

description: A phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha (human) that has had the initiator methionine removed. UniProtKB:O00443, 2-1686.


name: phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha isoform h1 (human)

description: A phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O00443-1.


name: lysosome-associated membrane glycoprotein 1 N-glycosylated 26 (human)

description: A lysosome-associated membrane glycoprotein 1 (human) that has been N-glycosylated at the residue equivalent to Asn-249 of the amino acid sequence represented by UniProtKB:P11279-1, in which the glycan composition is represented by GlyTouCan:G40664HB. Example: UniProtKB:P11279-1, Asn-249, MOD:00160~GNO:G40664HB.


An alpha-L-Fucp-(1->3)-D-Galp in which the carbon bearing the anomeric hydroxy group has alpha configuration.


name: plasma protease C1 inhibitor N-glycosylated 14 (human)

description: A plasma protease C1 inhibitor (human) that has been N-glycosylated at the residue equivalent to Asn-25 of the amino acid sequence represented by UniProtKB:P05155-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P05155-1, Asn-25, MOD:00160~GNO:G43417UB.


FIGO Stage IIIB Ovarian Cancer

description: Ovarian cancer with macroscopic, extrapelvic, peritoneal metastasis equal or less than 2 cm +/- positive retroperitoneal lymph nodes. Includes extension to capsule of liver/spleen. (FIGO, 2014)


name: chymotrypsin-like elastase family member 3B N-glycosylated 15 (human)

description: A chymotrypsin-like elastase family member 3B (human) that has been N-glycosylated at the residue equivalent to Asn-114 of the amino acid sequence represented by UniProtKB:P08861-1, in which the glycan structure is represented by GlyTouCan:G71367OV. Example: UniProtKB:P08861-1, Asn-114, MOD:00160~GNO:G71367OV.


name: brain-specific angiogenesis inhibitor 1-associated protein 2 isoform h5 (human)

description: A brain-specific angiogenesis inhibitor 1-associated protein 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9UQB8-5.


name: myristoylated alanine-rich C-kinase substrate phosphorylated 3 (human)

description: A myristoylated alanine-rich C-kinase substrate (human) that has been phosphorylated on the residue at the position equivalent to Ser-159 of the amino acid sequence represented by UniProtKB:P29966. UniProtKB:P29966, Ser-159, MOD:00046.


name: serine protease FAM111B methylated 4 (human)

description: A serine protease FAM111B (human) that has been methylated on the residue at the position equivalent to Cys-451 of the amino acid sequence represented by UniProtKB:Q6SJ93-1. Example: UniProtKB:Q6SJ93-1, Cys-451, MOD:00660.


name: Recurrent T Acute Lymphoblastic Leukemia

description: The reemergence of T-acute lymphoblastic leukemia after a period of remission.


name: Recurrent Childhood T Acute Lymphoblastic Leukemia

description: The reemergence of T-acute lymphoblastic leukemia in childhood after a period of remission.


protein GOLM2 O-glycosylated 5 (human)

A protein GOLM2 (human) that has been O-glycosylated at the residue equivalent to Ser-313 of the amino acid sequence represented by UniProtKB:Q6P4E1-4, in which the glycan composition is represented by GlyTouCan:G29068FM. Example: UniProtKB:Q6P4E1-4, Ser-313, MOD:00002~GNO:G29068FM.


name: prolyl 3-hydroxylase 2 deaminated 1 (human)

description: A prolyl 3-hydroxylase 2 (human) that has been deaminated on the residue at the position equivalent to Asn-449 of the amino acid sequence represented by UniProtKB:Q8IVL5-1. Example: UniProtKB:Q8IVL5-1, Asn-449, MOD:00684.


name: Ras GTPase-activating protein 3 isoform 1 (human)

description: A Ras GTPase-activating protein 3 isoform 1 that is encoded in the genome of human.


PRONAMIDE

A member of the class of benzamides resulting from the formal condensation of the carboxy group of 3,5-dichlorobenzoic acid with the amino group of 2-methylbut-3-yn-2-amine. It is used as a systemic post-emergent herbicide for the control grass and broadleaf weeds in a wide range of in a wide variety of fruit and root crops.


CLODINAFOP PROPARGYL

A carboxylic ester resulting from the formal condensation of the carboxy group of clodinafop with the hydroxy group of prop-2-yn-1-ol. It is widely used as a herbicide for the control of annual grass weeds in cereal crops.


A frizzled-like G-protein coupled receptor that is a translation product of the human FZD8 gene or a 1:1 ortholog thereof.


name: frizzled-8, signal peptide removed ubiquitinated form (human)

description: A frizzled-8 (human) that has had the signal peptide removed and that includes at least one ubiquitinated lysine. UniProtKB:Q9H461, 28-694, MOD:01148.


name: frizzled-8, signal peptide removed form (human)

description: A frizzled-8 (human) that has had the signal peptide removed. UniProtKB:Q9H461, 28-694.


sulfate transporter isoform 1 (human)

A sulfate transporter isoform 1 that is encoded in the genome of human.


name: microtubule-associated protein tau isoform Tau-F phosphorylated 1 (human)

description: A microtubule-associated protein tau isoform Tau-F phosphorylated 1 in human. UniProtKB:P10636-8, Thr-181, MOD:00047.


cardiomyopathy, golden hamster

description: Cardiomyopathy that occurs in golden hamster.


dilated cardiomyopathy, golden hamster

description: Dilated cardiomyopathy that occurs in golden hamster.


protein HEXIM1

A protein that is a translation product of the human HEXIM1 gene or a 1:1 ortholog thereof.


protein HEXIM1 deaminated 1 (human)

A protein HEXIM1 (human) that has been deaminated on the residue at the position equivalent to Gln-285 of the amino acid sequence represented by UniProtKB:O94992. UniProtKB:O94992, Gln-285, MOD:00685.


name: versican core protein O-glycosylated 155 (human)

description: A versican core protein (human) that has been O-glycosylated at the residue equivalent to Thr-2135 of the amino acid sequence represented by UniProtKB:P13611-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P13611-1, Thr-2135, MOD:00005~GNO:G43417UB.


name: DIS3-like exonuclease 2 deaminated 1 (human)

description: A DIS3-like exonuclease 2 (human) that has been deaminated on the residue at the position equivalent to Gln-527 of the amino acid sequence represented by UniProtKB:Q8IYB7-1. Example: UniProtKB:Q8IYB7-1, Gln-527, MOD:00685.


A hydroxyether that is propan-1-ol substituted by an ethoxy group at position 3.


name: FLVCR1-related retinopathy with or without ataxia

description: A disorder characterized by retinopathy with ataxia in most patients, caused by biallelic variants in the FLVCR1 gene.


name: posterior column ataxia-retinitis pigmentosa syndrome

description: Posterior column ataxia - retinitis pigmentosa is characterized by the association of progressive sensory ataxia and retinitis pigmentosa.


name: iron-sulfur clusters transporter ABCB7, mitochondrial isoform h2 (human)

description: An iron-sulfur clusters transporter ABCB7, mitochondrial (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O75027-2.


C-C motif chemokine 26

A C/C-C motif small inducible chemokine that is a translation product of the human CCL26 gene or a 1:1 ortholog thereof.


Mononegavirales infectious disease

description: Infections with viruses of the order mononegavirales. The concept includes filoviridae infections; paramyxoviridae infections; and rhabdoviridae infections.


name: parainfluenza virus type 2 infectious disease

description: A disease caused by infection with parainfluenza virus type 2.


name: fetal parainfluenza virus type 3 syndrome

description: A syndrome caused by HPIV-3.


name: parainfluenza virus type 3 infectious disease

description: Parainfluenza virus type 3 is one of a group of common viruses known as human parainfluenza viruses (HPIV) that cause a variety of respiratory illnesses. Symptoms usually develop between 2 and 7 days from the time of exposure and typically resolve in 7-10 days. Symptoms may include fever, runny nose, and cough. HPIV-3 can also cause bronchiolitis, bronchitis, and pneumonia. Infants and young children are particularly susceptible to HPIV-3 infections, though older adults and those with a weakened immune system are also at risk for complications. HPIVs are usually spread from an infected person to others through coughing, sneezing, and/or touching. There is currently no vaccine to protect against parainfluenza virus infections. Most HPIV infections resolve on their own and do not require special treatment, though medical intervention may be necessary for severe breathing problems. Most adults have antibodies against parainfluenza but can get repeat infections.


henipavirus infectious disease

description: Infections with viruses of the genus henipavirus, family paramyxoviridae.


Rhabdoviridae infectious disease

description: Virus diseases caused by rhabdoviridae. Important infections include rabies; ephemeral fever; and vesicular stomatitis.


borna virus encephalitis

description: A human disease caused by infection with Borna disease virus.


morbillivirus infectious disease

description: Infections with viruses of the genus morbillivirus, family paramyxoviridae. Infections mainly cause acute disease in their hosts, although in some cases infection is persistent and leads to degenerative conditions.


respirovirus infectious disease

description: Infections with viruses of the genus respirovirus, family paramyxoviridae. Host cell infection occurs by adsorption, via hemagglutinin, to the cell surface.


Paramyxoviridae infectious disease

description: Infections with viruses of the family paramyxoviridae. This includes morbillivirus infections; respirovirus infections; pneumovirus infections; henipavirus infections; avulavirus infections; and rubulavirus infections.


Filoviridae infectious disease

description: Infections with viruses of the family filoviridae. The infections in humans consist of a variety of clinically similar viral hemorrhagic fevers but the natural reservoir host is unknown.


name: parainfluenza virus type 4 infectious disease

description: A disease caused by infection with parainfluenza virus type 4.


name: parainfluenza virus type 1 infectious disease

description: A disease caused by infection with parainfluenza virus type 1.


Avulavirus infectious disease

description: Infections with viruses of the genus avulavirus, family paramyxoviridae. This includes newcastle disease and other infections of domestic fowl.


name: transcriptional activator Myb phosphorylated 1 (human)

description: A transcriptional activator Myb (human) that has been phosphorylated on the residue at the position equivalent to Ser-532 of the amino acid sequence represented by UniProtKB:P10242-1. Example: UniProtKB:P10242-1, Ser-532, MOD:00046.


name: synaptotagmin-like protein 3 isoform h2 (human)

description: A synaptotagmin-like protein 3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q4VX76-2.


name: adult central nervous system choriocarcinoma

description: A choriocarcinoma of the central nervous system that occurs in an adult.


TGF-beta 2 isoform A cleaved 1 (human)

A TGF-beta 2 isoform A cleaved 1 in human. UniProtKB:P61812-1, 303-414.


name: transforming growth factor beta-2 isoform A (human)

description: A TGF-beta 2 isoform A that is encoded in the genome of human.


TGF-beta 2 isoform A cleaved 3 (human)

A TGF-beta 2 isoform A cleaved 3 in human, in which the cleaved parts remain joined by disulfide bonds. UniProtKB:P61812-1, 20-302, 303-414.


TGF-beta 2 isoform A cleaved 2 (human)

A TGF-beta 2 isoform A cleaved 2 in human. UniProtKB:P61812-1, 20-302.


Ciliary Body Adenoma

description: A benign neoplasm of the pigmented ciliary epithelium (pigmented epithelial adenoma) and/ or the non-pigmented ciliary epithelium (non-pigmented epithelial adenoma). (WHO 2018)


A member of the class of dibenzofurans that is dibenzo[b,d]furan substituted by a hydroxy group at position 1 and chloro groups at positions 4 and 8 respectively.


name: cohesin subunit SA-2 methylated 1 (human)

description: A cohesin subunit SA-2 (human) that has been methylated on the residue at the position equivalent to Cys-487 of the amino acid sequence represented by UniProtKB:Q8N3U4-1. Example: UniProtKB:Q8N3U4-1, Cys-487, MOD:00660.


HEXACONAZOLE

A racemate comprising equimolar amounts of (R)- and (S)-hexaconazole. An agricultural fungicide introduced in the 1980s, it is not approved for use within the European Union.


(R)-hexaconazole

A 2-(2,4-dichlorophenyl)-1-(1H-1,2,4-triazol-1-yl)hexan-2-ol that has R configuration.


(S)-hexaconazole

A 2-(2,4-dichlorophenyl)-1-(1H-1,2,4-triazol-1-yl)hexan-2-ol that has S configuration.


An alpha-D-glucuronosyl diglyceride in which the acyl groups at the 1- and 2-positions are stearoyl (octadecanoyl) and palmitoyl (hexadecanoyl) respectively.


alpha-D-glucuronosyl diglyceride

A glucosylglycerol derivative consisting of a 1,2-diglyceride having an alpha-D-glucuronosyl residue attached at the 3-position.


An alpha-D-glucuronosyl diglyceride in which the acyl groups at the 1- and 2-positions are palmitoyl (hexadecanoyl) and (10R)-10-methyloctadecanoyl respectively.


An alpha-D-glucuronosyl diglyceride in which the acyl groups at the 1- and 2-positions are (10R)-10-methyloctadecanoyl and palmitoyl (hexadecanoyl) respectively.


name: vascular endothelial growth factor receptor 1 N-glycosylated 4 (human)

description: A vascular endothelial growth factor receptor 1 (human) that has been N-glycosylated at the residue equivalent to Asn-625 of the amino acid sequence represented by UniProtKB:P17948-1, in which the glycan composition is represented by GlyTouCan:G57776ZU. Example: UniProtKB:P17948-1, Asn-625, MOD:00160~GNO:G57776ZU.


name: inositol-tetrakisphosphate 1-kinase isoform h2 (human)

description: An inositol-tetrakisphosphate 1-kinase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q13572-2.


name: inositol-tetrakisphosphate 1-kinase isoform h1 (human)

description: An inositol-tetrakisphosphate 1-kinase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q13572-1.


(S)-tetrindole hydrochloride

A hydrochloride obtained by combining equimolar amounts of (S)-tetrindole and hydrochloric acid.


A D-galactosyl-N-acylsphingosine having a sulfo group at the 3-position on the galactose ring and tetracosanoyl as the N-acyl group.


protein Mpv17

A protein that is a translation product of the human MPV17 gene or a 1:1 ortholog thereof.


protein Mpv17 cysteinylated 1 (human)

A protein Mpv17 (human) that has been cysteinylated on the residue at the position equivalent to Cys-99 of the amino acid sequence represented by UniProtKB:P39210. UniProtKB:P39210, Cys-99, MOD:00765.


protein Mpv17 isoform 1 (human)

A protein Mpv17 isoform 1 that is encoded in the genome of human.


protein Mpv17 deaminated 1 (human)

A protein Mpv17 (human) that has been deaminated on the residue at the position equivalent to Asn-145 of the amino acid sequence represented by UniProtKB:P39210. UniProtKB:P39210, Asn-145, MOD:00684.


Smouldering systemic mastocytosis

description: Smouldering systemic mastocytosis is a type of systemic mastocytosis (SM). This clonal hematologic disease, with a slow progression, results in an accumulation of neoplastic mast cells in the visceral organs over time and patients present with splenomegaly, hypercellular marrow and, in some cases, urticaria pigmentosa-like skin lesions.


name: endosomal/lysosomal proton channel TMEM175 isoform h2 (human)

description: An endosomal/lysosomal proton channel TMEM175 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9BSA9-2.


5-nitrosalicylic acid

A monohydroxybenzoic acid in which the hydroxy group is ortho- to the carboxylic acid group and which has a nitro substituent para- to the phenolic hydroxy group.


name: solute carrier family 12 member 5 isoform h1 (human)

description: A solute carrier family 12 member 5 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9H2X9-1.


L-histidine derivative

A proteinogenic amino acid derivative resulting from the formal reaction of L-histidine at the amino group, carboxy group, or the imidazolyl moiety, or from the replacement of any hydrogen of L-histidine by a heteroatom.


An L-histidine derivative that is the ester obtained by formal condensation of the carboxy group of L-histidine with the 3'-hydroxy group of AMP.


progressive myoclonic epilepsy type 9

description: Any progressive myoclonic epilepsy in which the cause of the disease is a mutation in the LMNB2 gene.


name: tubulin beta-4A chain methylated 2 (human)

description: A tubulin beta-4A chain (human) that has been methylated on the residue at the position equivalent to Cys-211 of the amino acid sequence represented by UniProtKB:P04350. UniProtKB:P04350, Cys-211, MOD:00660.


name: glutamine-dependent NAD(+) synthetase phosphorylated 1 (human)

description: A glutamine-dependent NAD(+) synthetase (human) that has been phosphorylated on the residue at the position equivalent to Ser-308 of the amino acid sequence represented by UniProtKB:Q6IA69-1. Example: UniProtKB:Q6IA69-1, Ser-308, MOD:00046.


name: glutamine-dependent NAD(+) synthetase isoform h2 (human)

description: A glutamine-dependent NAD(+) synthetase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q6IA69-2.


name: glutamine-dependent NAD(+) synthetase isoform h1 (human)

description: A glutamine-dependent NAD(+) synthetase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q6IA69-1.


A member of the class of oxazolidines that is 1,3-oxazolidine which is substituted by two methyl groups, dichloroacetyl group and a methyl group at positions 2, 3 and 5, respectively. It is a herbicide safener.


name: serine/threonine-protein kinase LATS1 phosphorylated 3 (human)

description: A serine/threonine-protein kinase LATS1 (human) that has been phosphorylated on the residue at the position equivalent to Thr-1079 of the amino acid sequence represented by UniProtKB:O95835-1. Example: UniProtKB:O95835-1, Thr-1079, MOD:00047.


name: structural maintenance of chromosomes protein 1B

description: A protein that is a translation product of the human SMC1B gene or a 1:1 ortholog thereof.


name: structural maintenance of chromosomes protein 1B isoform h2 (human)

description: A structural maintenance of chromosomes protein 1B (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8NDV3-2.


name: structural maintenance of chromosomes protein 1B isoform h1 (human)

description: A structural maintenance of chromosomes protein 1B (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8NDV3-3.


name: structural maintenance of chromosomes protein 1B deaminated 1 (human)

description: A structural maintenance of chromosomes protein 1B (human) that has been deaminated on the residue at the position equivalent to Asn-40 of the amino acid sequence represented by UniProtKB:Q8NDV3-3. Example: UniProtKB:Q8NDV3-3, Asn-40, MOD:00684.


name: BOS complex subunit NOMO1 methylated 1 (human)

description: A BOS complex subunit NOMO1 (human) that has been methylated on the residue at the position equivalent to Cys-627 of the amino acid sequence represented by UniProtKB:Q15155. UniProtKB:Q15155, Cys-627, MOD:00660.


name: collagen alpha-4(IV) chain, signal peptide removed 5-hydroxy-lysine, 3-hydroxy-proline and 4-hydroxy-proline form (human)

description: A collagen alpha-4(IV) chain (human) that has had the signal peptide removed and that includes at least one 5-hydroxy-lysine, at least one 3-hydroxy-proline and at least one 4-hydroxy-proline. UniProtKB:P53420, 39-1690, MOD:00037|MOD:00038|MOD:00039.


name: collagen alpha-4(IV) chain 5-hydroxy-lysine, 3-hydroxy-proline and 4-hydroxy-proline form (human)

description: A collagen alpha-4(IV) chain (human) that includes at least one 5-hydroxy-lysine, at least one 3-hydroxy-proline and at least one 4-hydroxy-proline. UniProtKB:P53420, MOD:00037|MOD:00038|MOD:00039.


dipsogenic diabetes insipidus

description: Diabetes insipidus caused by excessive intake of water due to psychological factors or damage to the thirst-regulating mechanism.


A 1-aminopropan-2-ol that has R-configuration.


name: bone sialoprotein 2, signal peptide removed form (human)

description: A bone sialoprotein 2 (human) that has had the signal peptide removed. UniProtKB:P21815, 17-317.


name: bone sialoprotein 2 deaminated 1 (human)

description: A bone sialoprotein 2 (human) that has been deaminated on the residue at the position equivalent to Asn-282 of the amino acid sequence represented by UniProtKB:P21815. UniProtKB:P21815, Asn-282, MOD:00684.


name: beta-microseminoprotein isoform hPSP94 (human)

description: A beta-microseminoprotein (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P08118-1.


name: mothers against decapentaplegic homolog 4 sequence variant Q249* (human)

description: A mothers against decapentaplegic homolog 4 (human) that has has been truncated after the position equivalent to Gln-248 of the amino acid sequence represented by UniProtKB:Q13485. UniProtKB:Q13485, 1-248.


name: E3 ubiquitin-protein ligase RNF6 deaminated 1 (human)

description: An E3 ubiquitin-protein ligase RNF6 (human) that has been deaminated on the residue at the position equivalent to Gln-187 of the amino acid sequence represented by UniProtKB:Q9Y252-1. Example: UniProtKB:Q9Y252-1, Gln-187, MOD:00685.


A fifteen-membered glycopeptide comprising glycyl, homoleucyl, alanyl, glycyl, cyclohexylalanyl, (5R)-5-(beta-D-galactopyranosyloxy)lysyl, glycyl. alpha-glutamyl, glutaminyl, glycyl, prolyl, lysyl, glycyl, alpha-glutamyl and threonine residues coupled in sequence.


A 1-monoglyceride that has stearoyl as the acyl group.


A 3-acyl-sn-glycerol that has octadecanoyl (stearoyl) as the 3-acyl group.


VISCUMNEOSIDE V

A viscumneoside that is viscumneoside III in which the primary hydroxy group of the beta-D-apiofuranosyl moiety has itself been converted to the corresponding beta-D-apiofuranoside derivative. Found in Viscum coloratum, an evergreen hemiparasitic plant whose stems and leaves are used in traditional Chinese medicine for the treatment of rheumatism.


adult papillary meningioma

description: A papillary meningioma occurring in adults.


name: leucine zipper transcription factor-like protein 1 isoform 1 (human)

description: A leucine zipper transcription factor-like protein 1 isoform 1 that is encoded in the genome of human.


name: gamma-aminobutyric acid receptor subunit beta-1

description: A GABA(A) receptor protein that is a translation product of the human GABRB1 gene or a 1:1 ortholog thereof.


name: gamma-aminobutyric acid receptor subunit beta-1, signal peptide removed form (human)

description: A gamma-aminobutyric acid receptor subunit beta-1 (human) that has had the signal peptide removed. UniProtKB:P18505, 26-474.


name: gamma-aminobutyric acid receptor subunit beta-1 isoform h2 (human)

description: A gamma-aminobutyric acid receptor subunit beta-1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P18505-2.


name: gamma-aminobutyric acid receptor subunit beta-1 isoform 1 (human)

description: A gamma-aminobutyric acid receptor subunit beta-1 isoform 1 that is encoded in the genome of human.


A protein that is a translation product of the human TSTD1 gene or a 1:1 ortholog thereof.


name: thiosulfate:glutathione sulfurtransferase isoform h2 (human)

description: A thiosulfate:glutathione sulfurtransferase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8NFU3-2.


name: thiosulfate:glutathione sulfurtransferase isoform h1 (human)

description: A thiosulfate:glutathione sulfurtransferase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8NFU3-1.


name: thiosulfate:glutathione sulfurtransferase isoform h4 (human)

description: A thiosulfate:glutathione sulfurtransferase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8NFU3-4.


name: thiosulfate:glutathione sulfurtransferase isoform h3 (human)

description: A thiosulfate:glutathione sulfurtransferase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8NFU3-3.


cyclitol

A polyol consisting of a cycloalkane containing at least three hydroxy groups, each attached to a different ring carbon atom.


A myo-inositol tetrakisphosphate having the four phosphate groups at the 1-, 4-, 5- and 6-positions.


nebramycin 5'

A carbamoylkanamycin that is tobramycin bearing a single carbamoyl substituent located at position 6'' (on the 3-aminoglucose ring).


A myo-inositol pentakisphosphate that consists of 1D-myo-inositol having the five phospho groups located at positions 1, 2, 3, 4 and 5 as well as a diphospho group at position 6.


1D-myo-inositol 6-phosphate

A myo-inositol monophosphate in which the phosphate group is located at position 6.


inositol 1-phosphate

An inositol having myo- configuration substituted at position 1 by a phosphate group.


A cyclitol that is valiolone in which the the stereochemistry at position 2 has been inverted (from R to S).


A myo-inositol tetrakisphosphate that consists of myo-inositol having the four phospho groups located at positions 2, 3, 4 and 6 as well as a diphospho group at position 5.


amino cyclitol

Any cyclitol having one or more alcoholic hydroxy groups replaced by substituted or unsubstituted amino groups.


inositol

Any cyclohexane-1,2,3,4,5,6-hexol.


6''-O-carbamoylkanamycin A

A carbamoylkanamycin that is kanamycin A bearing a single carbamoyl substituent located at position 6'' (on the 3-aminoglucose ring).


A 1D-myo-inositol pentakisphosphate compound with a diphosphate groups attached at the 4-position.


A 1D-myo-inositol tetrakisphosphate compound of unknown isomeric configuration with diphosphate groups attached at the two remainig vacant positions.


A 1D-myo-inositol bis(diphosphate) tetrakisphosphate having the two diphospho groups located at positions 1 and 3.


A myo-inositol tetrakisphosphate that consists of myo-inositol having the four phospho groups located at positions 3, 4, 5 and 6 as well as a diphospho group at position 1.


myo-inositol phosphate

An inositol phosphate in which the inositol component has myo-configuration.


5-epi-valiolone 7-phosphate

A member of the class of cyclitols that is 5-epi-valiolone carrying a phospho substituent at position 7.


A cyclitol phosphate that is 5a-carba-beta-D-mannose having a (4S,8S,12S,16S,20S)-4,8,12,16,20-pentamethylheptacosyl)phosphate group at position 1.


valiolone

A cyclitol that is cyclohexanone which is substituted by hydroxy groups at positions 2, 3, 4, and 5, and by a hydroxymethyl group at position 5 (the 2R,3S,4S,5S stereoisomer).


fytic acid

A myo-inositol hexakisphosphate in which each hydroxy group of myo-inositol is monophosphorylated.


A glycoside phosphate that is ribostamycin (vistamycin) in which the ribofuranosyl residue is substituted at position 5 by a phosphate group.


A 1D-myo-inositol bis(diphosphate) trisphosphate having the three phospho groups located at positions 1, 4 and 6 and the two diphospho groups at positions 3 and 5.


A scyllo-inositol phosphate that is 1D-3-amino-1-guanidino-1,3-dideoxy-scyllo-inositol carrying a single phospho substituent at position 6.


A myo-inositol tetrakisphosphate having the four phosphate groups placed at the 3-, 4-, 5- and 6-positions.


validone 7-phosphate

A cyclitol phosphate that is validone carrying a single monophosphate substituent at position 7.


streptidine 6-phosphate

A derivative of streptidine having a phosphate group at the 6-position.


A myo-inositol pentakisphosphate comprising 1D-myo-inositol having the five phosphate groups placed in the 1-' 2-' 4-, 5- and 6-positions.


dihydrostreptomycin 6-phosphate

The 6-O-phospho derivative of dihydrostreptomycin.


Any myo-inositol trisphosphate bearing two additional diphospho substituents.


A myo-inositol tetrakisphosphate that consists of myo-inositol having the four phospho groups located at positions 1, 4, 5 and 6 as well as a diphospho group at position 3.


A 1D-myo-inositol bis(diphosphate) tetrakisphosphate having the two diphospho groups located at positions 5 and 6.


2-deoxystreptamine derivative

Any derivative of 2-deoxystreptamine.


validamine 7-phosphate

A cyclitol phosphate that is validamine carrying a single monophosphate substituent at position 7.


A scyllo-inositol phosphate having a monophosphate group at the 4-position as well as the hydroxy group at the 1-position replaced by an amino group.


1D-myo-inositol 2-phosphate

A myo-inositol monophosphate in which the phosphate group is located at the 2-position.


GDP-valienol

A nucleotide conjugate consisting of CDP joined at the 1-position of valienol via a diphosphate linkage.


streptamine 5-phosphate

a scyllo-inositol phosphate compound having a phosphate group in the 5-position and amino groups in place of hydroxy groups in the 1- and 3-positions.


valienol 1-phosphate

A cyclitol phosphate that is valienol carrying a sigle monophosphate group at position 1.


A 1D-myo-inositol bis(diphosphate) tetrakisphosphate having the two diphospho groups located at positions 1 and 4.


A scyllo-inositol phosphate compound having the phosphate group at the 6-position, guanidino groups replacing hydroxy functions at the 1-position and an alpha-L-lyxofuranosyl residue at the 4-position.


A scyllo-inositol phosphate having the phosphate at the 4-position and a guanidino group in place of the hydroxyl at position 1.


A myo-inositol pentakisphosphate that consists of myo-inositol having the five phospho groups located at positions 1, 2, 4, 5 and 6 as well as a diphospho group at position 3.


(+)-conduritol B

A conduritol which has 1S,2R,3R,4S configuration.


A myo-inositol pentakisphosphate that consists of 1D-myo-inositol having the five phospho groups located at positions 1, 2, 3, 4 and 6 as well as a diphospho group at position 5.


diphosphoinositol polyphosphate

An inositol phosphate that is inositol substituted by one or more diphosphate groups and with multiple monophosphate groups attached.


streptomycin 3''-phosphate

A streptomycin phosphate having the phosphate group placed at the 3''-position.


myo-inositol monophosphate

A myo-inositol phosphate that is myo-inositol in which one of the hydroxy groups is replaced by a phosphate group. A 'closed class'.


A 1D-myo-inositol bis(diphosphate) tetrakisphosphate having the two diphospho groups located at positions 4 and 5.


1D-myo-inositol 5-phosphate

An inositol having myo- configuration substituted at position 5 by a phosphate group.


(-)-conduritol B

A conduritol which has 1R,2S,3S,4R configuration.


A myo-inositol bis(diphosphate) trisphosphate having the three phospho groups located at positions 4, 5 and 6 and the two diphospho groups at positions 1 and 3.


A myo-inositol pentakisphosphate that consists of myo-inositol having the five phospho groups located at positions 2, 3, 4, 5 and 6 as well as a diphospho group at position 1.


An inositol phosphate consisting of two units of 1L-myo-inositol phosphate in which the phosphate group of the first is joined to the 3-position of the second.


carbamoylkanamycin

Any kanamycin carrying one or more carbamoyl substituents


1D-myo-inositol 3,4,6-trisphosphate

A myo-inositol trisphosphate having the three phosphate groups at the 3-, 4-, and 6-positions.


An oligosaccharide phosphate consisting of D-myo-inositol having a 6-O-(2-aminoethylphosphono)-alpha-D-mannosyl-(1->2)-alpha-D-mannosyl-(1->6)-alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl residue attached at the 6-position.


1D-myo-inositol 2,4-bisphosphate

A myo-inositol bisphosphate in which the two phosphate groups are located at positions 2 and 4.


A myo-inositol pentakisphosphate that consists of myo-inositol having the five phospho groups located at positions 1, 2, 3, 4 and 6 as well as a triphospho group at position 5.


2-epi-5-epi-valiolone 7-phosphate

A member of the class of cyclitols that is 2-epi-5-epi-valiolone carrying a phospho substituent at position 7.


A myo-inositol tetrakisphosphate having the four phosphates placed in the 1-, 2-, 5- and 6-positions.


A 1D-myo-inositol bis(diphosphate) tetrakisphosphate having the two diphospho groups located at positions 1 and 5.


A 1D-myo-inositol bis(diphosphate) tetrakisphosphate having the two diphospho groups located at positions 3 and 5.


1D-myo-inositol 3,5-bisphosphate

A myo-inositol bisphosphate in which the two phosphate groups are located at positions 3 and 5


conduritol A

A conduritol in which the hydroxy groups at positions 2, 3, and 4 are in a trans,trans,cis- relationship to that at position 1.


A 1D-myo-inositol bis(diphosphate) trisphosphate having the three phospho groups located at positions 3, 4 and 6 and the two diphospho groups at positions 1 and 5.


validoxylamine A 7'-phosphate

A cyclitol phosphate that is validoxylamine A carrying a single monophosphate substituent at position 7'.


myo-inositol 1,3,4,6-tetrakisphosphate

A myo-inositol tetrakisphosphate having the phosphate groups placed at the 1-, 3-, 4- and 6-positions.


name: B Acute Lymphoblastic Leukemia with Intrachromosomal Amplification of Chromosome 21

description: B-acute lymphoblastic leukemia characterized by amplification of a portion of chromosome 21. It usually occurs in children and is associated with an adverse prognosis.


RILP-like protein 1

A protein that is a translation product of the human RILPL1 gene or a 1:1 ortholog thereof.


RILP-like protein 1 isoform h3 (human)

A RILP-like protein 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q5EBL4-3.


RILP-like protein 1 isoform h1 (human)

A RILP-like protein 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q5EBL4-1.


RILP-like protein 1 isoform h2 (human)

A RILP-like protein 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q5EBL4-2.


name: partner and localizer of BRCA2 sequence variant E1002* (human)

description: A partner and localizer of BRCA2 (human) that has has been truncated after the position equivalent to Lys-1001 of the amino acid sequence represented by UniProtKB:Q86YC2. UniProtKB:Q86YC2, 1-1001.


name: Testicular Mixed Germ Cell-Sex Cord-Stromal Tumor

description: A testicular mixed germ cell-sex cord-stromal tumor in which the neoplastic germ cells and the neoplastic sex cord-stromal cells do not form nests and are instead arranged in a diffuse pattern.


Empyema with fistula

description: An empyema with a fistula.


protein NDRG3 phosphorylated 1 (human)

A protein NDRG3 (human) that has been phosphorylated on the residue at the position equivalent to Thr-183 of the amino acid sequence represented by UniProtKB:Q9UGV2-1. Example: UniProtKB:Q9UGV2-1, Thr-183, MOD:00047.


protein NDRG3

A protein that is a translation product of the human NDRG3 gene or a 1:1 ortholog thereof.


protein NDRG3 deaminated 3 (human)

A protein NDRG3 (human) that has been deaminated on the residue at the position equivalent to Asn-202 of the amino acid sequence represented by UniProtKB:Q9UGV2-1. Example: UniProtKB:Q9UGV2-1, Asn-202, MOD:00684.


protein NDRG3 methylated 1 (human)

A protein NDRG3 (human) that has been methylated on the residue at the position equivalent to Cys-166 of the amino acid sequence represented by UniProtKB:Q9UGV2-1. Example: UniProtKB:Q9UGV2-1, Cys-166, MOD:00660.


protein NDRG3 deaminated 1 (human)

A protein NDRG3 (human) that has been deaminated on the residue at the position equivalent to Asn-184 of the amino acid sequence represented by UniProtKB:Q9UGV2-1. Example: UniProtKB:Q9UGV2-1, Asn-184, MOD:00684.


protein NDRG3 isoform h2 (human)

A protein NDRG3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9UGV2-2.


protein NDRG3 deaminated 2 (human)

A protein NDRG3 (human) that has been deaminated on the residue at the position equivalent to Gln-196 of the amino acid sequence represented by UniProtKB:Q9UGV2-1. Example: UniProtKB:Q9UGV2-1, Gln-196, MOD:00685.


protein NDRG3 isoform 1 (human)

A protein NDRG3 isoform 1 that is encoded in the genome of human.


protein NDRG3 isoform h3 (human)

A protein NDRG3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9UGV2-3.


protein NDRG3 cysteinylated 1 (human)

A protein NDRG3 (human) that has been cysteinylated on the residue at the position equivalent to Cys-254 of the amino acid sequence represented by UniProtKB:Q9UGV2-1. Example: UniProtKB:Q9UGV2-1, Cys-254, MOD:00765.


name: vesicle transport through interaction with t-SNAREs homolog 1B isoform Long (human)

description: A vesicle transport through interaction with t-SNAREs homolog 1B isoform 1 that is encoded in the genome of human.


protein PRRC2C isoform h7 (human)

A protein PRRC2C (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9Y520-7.


name: actin nucleation-promoting factor WAS, initiator methionine removed phosphorylated 1 (human)

description: An actin nucleation-promoting factor WAS (human) that has had the initiator methionine removed and that has been phosphorylated on the residue at the position equivalent to Tyr-291 of the amino acid sequence represented by UniProtKB:P42768. UniProtKB:P42768, 2-502, Tyr-291, MOD:00048.


cysteinyl leukotriene receptor

A leukotriene receptor that in active form binds cysteinyl leukotriene.


cysteinyl leukotriene receptor 1

A cysteinyl leukotriene receptor that is a translation product of the human CYSLTR1 gene or a 1:1 ortholog thereof. The preferred ligand is the cysteinyl leukotriene D4.


name: cysteinyl leukotriene receptor 1 methylated 1 (human)

description: A cysteinyl leukotriene receptor 1 (human) that has been methylated on the residue at the position equivalent to Cys-289 of the amino acid sequence represented by UniProtKB:Q9Y271. UniProtKB:Q9Y271, Cys-289, MOD:00660.


cysteinyl leukotriene receptor 2

A cysteinyl leukotriene receptor that is a translation product of the human CYSLTR2 gene or a 1:1 ortholog thereof. The preferred ligand is the cysteinyl leukotriene C4.


name: pleckstrin homology domain-containing family A member 7 phosphorylated 1 (human)

description: A pleckstrin homology domain-containing family A member 7 (human) that has been phosphorylated on the residue at the position equivalent to Thr-477 of the amino acid sequence represented by UniProtKB:Q6IQ23-1. Example: UniProtKB:Q6IQ23-1, Thr-477, MOD:00047.


name: Luc7-like protein 3 methylated 1 (human)

description: A Luc7-like protein 3 (human) that has been methylated on the residue at the position equivalent to Cys-35 of the amino acid sequence represented by UniProtKB:O95232-1. Example: UniProtKB:O95232-1, Cys-35, MOD:00660.


A pseudoguaianolide with anti-inflammatory activity isolated from the aerial parts of Inula hupehensis


name: proliferation-associated protein 2G4, initiator methionine removed form (human)

description: A proliferation-associated protein 2G4 (human) that has had the initiator methionine removed. Example: UniProtKB:Q9UQ80-1, 2-394.


name: endoplasmic reticulum aminopeptidase 2 isoform h3 (human)

description: An endoplasmic reticulum aminopeptidase 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q6P179-3.


name: C-Jun-amino-terminal kinase-interacting protein 4 isoform h6 (human)

description: A C-Jun-amino-terminal kinase-interacting protein 4 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O60271-9.


beta-chimaerin isoform h7 (human)

A beta-chimaerin (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P52757-7.


name: congenital plasminogen activator inhibitor type 1 deficiency

description: Congenital plasminogen activator inhibitor type 1 (PAI-1) deficiency is a rare genetic bleeding disorder characterized by premature lysis of hemostatic clots and a moderate bleeding tendency.


ROTIORINOL C

An azaphilone that is 9,9a-dihydro-2H-furo[3,2-g]isochromen-2-one substituted by an acetyl group at position 3, a hydroxy group at position 9, a 7-hydroxy-3,5-dimethylhepta-1,3-dien-1-yl group at position 6 and a methyl group at position 9a. It has been isolated from Chaetomium cupreum and exhibits antifungal activity.


name: Advanced Chromophobe Renal Cell Carcinoma

description: Chromophobe renal cell carcinoma that has spread extensively to other anatomic sites or is no longer responding to treatment.


Advanced Adenocarcinoma

description: An adenocarcinoma that has spread extensively to other anatomic sites or is no longer responding to treatment.


name: Advanced Progesterone Receptor-Positive Breast Carcinoma

description: Progesterone receptor-positive breast carcinoma that has spread extensively to other anatomic sites or is no longer responding to treatment.


name: Advanced Ovarian Clear Cell Adenocarcinoma

description: Ovarian clear cell adenocarcinoma that has spread extensively to other anatomic sites or is no longer responding to treatment.


name: Advanced Endometrial Endometrioid Adenocarcinoma

description: Endometrial endometrioid adenocarcinoma that has spread extensively to other anatomic sites or is no longer responding to treatment.


description: Intrahepatic cholangiocarcinoma that has spread extensively to other anatomic sites or is no longer responding to treatment.


Advanced Sebaceous Carcinoma

description: Sebaceous carcinoma that has spread extensively to other anatomic sites or is no longer responding to treatment.


name: Advanced Distal Bile Duct Adenocarcinoma

description: Distal bile duct adenocarcinoma that has spread extensively to other anatomic sites or is no longer responding to treatment.


Advanced renal cell carcinoma

description: Renal cell carcinoma that has spread extensively to other anatomic sites or is no longer responding to treatment.


name: Advanced Prostate Adenocarcinoma with Neuroendocrine Differentiation

description: Prostate adenocarcinoma with neuroendocrine differentiation that has spread extensively to other anatomic sites or is no longer responding to treatment.


Advanced Gastric Adenocarcinoma

description: Gastric adenocarcinoma that has spread extensively to other anatomic sites or is no longer responding to treatment.


name: Advanced Hormone Receptor-Negative Breast Carcinoma

description: Hormone receptor-negative breast carcinoma that has spread extensively to other anatomic sites or is no longer responding to treatment.


name: Advanced Unclassified Renal Cell Carcinoma

description: A renal cell carcinoma, not otherwise specified, that has spread extensively to other anatomic sites or is no longer responding to treatment.


name: Advanced Triple-Negative Breast Carcinoma

description: Triple-negative breast carcinoma that has spread extensively to other anatomic sites or is no longer responding to treatment.


Advanced Cervical Adenocarcinoma

description: A cervical adenocarcinoma that has spread extensively to other anatomic sites or is no longer responding to treatment.


Advanced Hepatocellular Carcinoma

description: Hepatocellular carcinoma that has spread extensively to other anatomic sites or is no longer responding to treatment.


Advanced Cholangiocarcinoma

description: A cholangiocarcinoma that has spread extensively to other anatomic sites or is no longer responding to treatment.


name: Advanced Estrogen Receptor-Positive Breast Carcinoma

description: Estrogen receptor-positive breast carcinoma that has spread extensively to other anatomic sites or is no longer responding to treatment.


Advanced Endometrial Adenocarcinoma

description: Endometrial adenocarcinoma that has spread extensively to other anatomic sites or is no longer responding to treatment.


name: Advanced Primary Peritoneal High Grade Serous Adenocarcinoma

description: A primary peritoneal high-grade serous adenocarcinoma that has spread extensively to other anatomic sites or is no longer responding to treatment.


Advanced Breast Adenocarcinoma

description: Breast adenocarcinoma that has spread extensively to other anatomic sites or is no longer responding to treatment.


Advanced Appendix Adenocarcinoma

description: Appendix adenocarcinoma that has spread extensively to other anatomic sites or is no longer responding to treatment.


name: Advanced Sarcomatoid Renal Cell Carcinoma

description: Sarcomatoid renal cell carcinoma that has spread extensively to other anatomic sites or is no longer responding to treatment.


Advanced Hilar Cholangiocarcinoma

description: Hilar cholangiocarcinoma that has spread extensively to other anatomic sites or is no longer responding to treatment.


name: Advanced Clear Cell Renal Cell Carcinoma

description: A clear cell renal cell carcinoma that has spread extensively to other anatomic sites or is no longer responding to treatment.


name: Advanced Fallopian Tube High Grade Serous Adenocarcinoma

description: A fallopian tube high-grade serous adenocarcinoma that has spread extensively to other anatomic sites or is no longer responding to treatment.


Advanced Adult Hepatocellular Carcinoma

description: A hepatocellular carcinoma that occurs during adulthood and has spread extensively to other anatomic sites or is no longer responding to treatment.


Advanced Papillary Renal Cell Carcinoma

description: A papillary renal cell carcinoma that has spread extensively to other anatomic sites or is no longer responding to treatment.


name: Advanced Endometrial Serous Adenocarcinoma

description: Endometrial serous adenocarcinoma that has spread extensively to other anatomic sites or is no longer responding to treatment.


Advanced Vaginal Adenocarcinoma

description: Vaginal adenocarcinoma that has spread extensively to other anatomic sites or is no longer responding to treatment.


name: Advanced Gastroesophageal Junction Adenocarcinoma

description: Gastroesophageal junction adenocarcinoma that has spread extensively to other anatomic sites or is no longer responding to treatment.


Advanced Colorectal Adenocarcinoma

description: Colorectal adenocarcinoma that has spread extensively to other anatomic sites or is no longer responding to treatment.


Advanced Esophageal Adenocarcinoma

description: Esophageal adenocarcinoma that has spread extensively to other anatomic sites or is no longer responding to treatment.


Advanced HER2-Positive Breast Carcinoma

description: HER2-positive breast carcinoma that has spread extensively to other anatomic sites or is no longer responding to treatment.


Advanced Pancreatic Adenocarcinoma

description: Pancreatic adenocarcinoma that has spread extensively to other anatomic sites or is no longer responding to treatment.


name: Advanced Adenocarcinoma of Unknown Primary

description: An adenocarcinoma of unknown primary that has spread extensively to other anatomic sites or is no longer responding to treatment.


name: Advanced Hormone Receptor-Positive Breast Carcinoma

description: Hormone receptor-positive breast carcinoma that has spread extensively to other anatomic sites or is no longer responding to treatment.


name: Advanced Pancreatic Ductal Adenocarcinoma

description: Pancreatic ductal adenocarcinoma that has spread extensively to other anatomic sites or is no longer responding to treatment.


Advanced Rectal Adenocarcinoma

description: Rectal adenocarcinoma that has spread extensively to other anatomic sites or is no longer responding to treatment.


Advanced Lung Adenocarcinoma

description: Lung adenocarcinoma that has spread extensively to other anatomic sites or is no longer responding to treatment.


Advanced Colon Adenocarcinoma

description: Colon adenocarcinoma that has spread extensively to other anatomic sites or is no longer responding to treatment.


Advanced Adrenal Cortical Carcinoma

description: Adrenal cortical carcinoma that has spread extensively to other anatomic sites or is no longer responding to treatment.


Advanced Fibrolamellar Carcinoma

description: Fibrolamellar carcinoma that has spread extensively to other anatomic sites or is no longer responding to treatment.


Advanced Endometrioid Adenocarcinoma

description: Endometrioid adenocarcinoma that has spread extensively from the original site of growth to other anatomic sites or is no longer responding to treatment.


Advanced HER2-Negative Breast Carcinoma

description: A HER2-negative breast adenocarcinoma that has spread extensively to other anatomic sites or is no longer responding to treatment.


Advanced Prostate Adenocarcinoma

description: A prostatic adenocarcinoma that has spread extensively to other anatomic sites or is no longer responding to treatment.


name: Advanced Ovarian Endometrioid Adenocarcinoma

description: Ovarian endometrioid adenocarcinoma that has spread extensively to other anatomic sites or is no longer responding to treatment.


keratin, type II cytoskeletal 2 oral

A protein that is a translation product of the human KRT76 gene or a 1:1 ortholog thereof.


name: hematopoietic prostaglandin D synthase isoform 1 (human)

description: A glutathione-requiring prostaglandin D synthase isoform 1 that is encoded in the genome of human.


name: serine protease FAM111B methylated 2 (human)

description: A serine protease FAM111B (human) that has been methylated on the residue at the position equivalent to Cys-43 of the amino acid sequence represented by UniProtKB:Q6SJ93-1. Example: UniProtKB:Q6SJ93-1, Cys-43, MOD:00660.


name: Set1/Ash2 histone methyltransferase complex subunit ASH2 isoform h3 (human)

description: A Set1/Ash2 histone methyltransferase complex subunit ASH2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9UBL3-3.


name: CMRF35-like molecule 8 isoform h4 (human)

description: A CMRF35-like molecule 8 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9UGN4-4.


name: CMRF35-like molecule 8 methylated 1 (human)

description: A CMRF35-like molecule 8 (human) that has been methylated on the residue at the position equivalent to Cys-15 of the amino acid sequence represented by UniProtKB:Q9UGN4-1. Example: UniProtKB:Q9UGN4-1, Cys-15, MOD:00660.


name: CMRF35-like molecule 8 cysteinylated 1 (human)

description: A CMRF35-like molecule 8 (human) that has been cysteinylated on the residue at the position equivalent to Cys-15 of the amino acid sequence represented by UniProtKB:Q9UGN4-1. Example: UniProtKB:Q9UGN4-1, Cys-15, MOD:00765.


name: CMRF35-like molecule 8, signal peptide removed form (human)

description: A CMRF35-like molecule 8 (human) that has had the signal peptide removed. Example: UniProtKB:Q9UGN4-1, 18-299.


name: CMRF35-like molecule 8 isoform h3 (human)

description: A CMRF35-like molecule 8 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9UGN4-3.


name: CMRF35-like molecule 8 isoform h1 (human)

description: A CMRF35-like molecule 8 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9UGN4-1.


name: CMRF35-like molecule 8 isoform h2 (human)

description: A CMRF35-like molecule 8 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9UGN4-2.


name: lysosome membrane protein 2 isoform 1 (human)

description: A lysosome membrane protein 2 isoform 1 that is encoded in the genome of human.


name: Locally Advanced Unresectable Gallbladder Carcinoma

description: Gallbladder carcinoma that has spread from its original site of growth to nearby tissues or lymph nodes and is not amenable to surgical resection.


name: autosomal dominant nonsyndromic hearing loss 17

description: Any autosomal dominant nonsyndromic deafness in which the cause of the disease is a mutation in the MYH9 gene.


SAMADERINS C

A quassinoid  isolated from Quassia indica and has been shown to exhibit antineoplastic activity.


name: E3 ubiquitin-protein ligase Hakai isoform h2 (human)

description: An E3 ubiquitin-protein ligase Hakai (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q75N03-2.


name: E3 ubiquitin-protein ligase Hakai methylated 1 (human)

description: An E3 ubiquitin-protein ligase Hakai (human) that has been methylated on the residue at the position equivalent to Cys-73 of the amino acid sequence represented by UniProtKB:Q75N03-1. Example: UniProtKB:Q75N03-1, Cys-73, MOD:00660.


name: serine/threonine-protein kinase tousled-like 2 isoform 3 (human)

description: A serine/threonine-protein kinase tousled-like 2 isoform 3 that is encoded in the genome of human.


name: solute carrier family 2, facilitated glucose transporter member 2 O-glycosylated 1 (human)

description: A solute carrier family 2, facilitated glucose transporter member 2 (human) that has been O-glycosylated at the residue equivalent to Thr-69 of the amino acid sequence represented by UniProtKB:P11168-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P11168-1, Thr-69, MOD:00005~GNO:G43417UB.


synphilin-1 isoform h1 (human)

A synphilin-1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9Y6H5-1.


cacibiocin A

An aminocoumarin resulting from the formal condensation of one of the carboxy groups of pyrrole-2,5-dicarboxylic acid with the amino group of 3-amino-4,7-dihydroxycoumarin. It is a natural product isolated from Catenulispora acidiphila that doesn't exhibit an antimicrobial activity contrary to most aminocoumarins.


Stage IIIA Uveal Melanoma AJCC v7

description: Stage IIIA includes: (T2c-d, N0, M0); (T3b-c, N0, M0); (T4a, N0, M0).  T2c: Ciliary body and choroid: Tumor size category 2 without ciliary body involvement but with extraocular extension less than or equal to 5 mm in diameter. T2d: Ciliary body and choroid: Tumor size category 2 with ciliary body involvement and extraocular extension less than or equal to 5 mm in diameter. T3b: Ciliary body and choroid: Tumor size category 3 with ciliary body involvement. T3c: Ciliary body and choroid: Tumor size category 3 without ciliary body involvement but with extraocular extension less than or equal to 5 mm in diameter. T4a: Iris: Tumor with extrascleral extension less than or equal to 5 mm in diameter.  Ciliary body and choroid: Tumor size category 4 without ciliary body involvement and extraocular extension.  N0: No regional lymph node metastasis.  M0: No distant metastasis.  (AJCC 7th ed.)


dTDP

A thymidine phosphate having a diphosphate group at the 5'-position.


name: BLOC-3 complex member HPS4 isoform h4 (human)

description: A BLOC-3 complex member HPS4 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9NQG7-4.


eIF5-mimic protein 2 isoform h1 (human)

An eIF5-mimic protein 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q7L1Q6-1.


CLETHROIDOSIDE E

A triterpenoid saponin that is (3beta,16alpha)-13,28-epoxyoleanane-3,16-diol attached to a  tetrasaccharide residue at position 3 via a glycosidic linkage. It has been isolated from the aerial parts of Lysimachia clethroides.


name: calmodulin-like protein 4 isoform h1 (human)

description: A calmodulin-like protein 4 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q96GE6-1.


name: protein phosphatase 1 regulatory subunit 12C isoform h2 (human)

description: A protein phosphatase 1 regulatory subunit 12C (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9BZL4-2.


name: protein phosphatase 1 regulatory subunit 12C

description: A protein that is a translation product of the human PPP1R12C gene or a 1:1 ortholog thereof.


name: protein phosphatase 1 regulatory subunit 12C acetylated 1 (human)

description: A protein phosphatase 1 regulatory subunit 12C (human) that has been acetylated on the residue at the position equivalent to Lys-198 of the amino acid sequence represented by UniProtKB:Q9BZL4-1. Example: UniProtKB:Q9BZL4-1, Lys-198, MOD:00723.


name: protein phosphatase 1 regulatory subunit 12C isoform h5 (human)

description: A protein phosphatase 1 regulatory subunit 12C (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9BZL4-5.


name: protein phosphatase 1 regulatory subunit 12C methylated 1 (human)

description: A protein phosphatase 1 regulatory subunit 12C (human) that has been methylated on the residue at the position equivalent to Cys-494 of the amino acid sequence represented by UniProtKB:Q9BZL4-1. Example: UniProtKB:Q9BZL4-1, Cys-494, MOD:00660.


name: protein phosphatase 1 regulatory subunit 12C phosphorylated 1 (human)

description: A protein phosphatase 1 regulatory subunit 12C (human) that has been phosphorylated on the residue at the position equivalent to Tyr-152 of the amino acid sequence represented by UniProtKB:Q9BZL4-1. Example: UniProtKB:Q9BZL4-1, Tyr-152, MOD:00048.


name: protein phosphatase 1 regulatory subunit 12C isoform h1 (human)

description: A protein phosphatase 1 regulatory subunit 12C (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9BZL4-1.


name: protein phosphatase 1 regulatory subunit 12C isoform h4 (human)

description: A protein phosphatase 1 regulatory subunit 12C (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9BZL4-4.


name: protein phosphatase 1 regulatory subunit 12C isoform h3 (human)

description: A protein phosphatase 1 regulatory subunit 12C (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9BZL4-3.


protein SSX1

A protein that is a translation product of the human SSX1 gene or a 1:1 ortholog thereof.


UDP-N-acetyltunicamine-uracil

A UDP-amino sugar that is an intermediate in the biosynthesis of the tunicamycins.


acne keloid

description: A chronic eruption of fibrous papules that develop and fuse to form a thick sclerotic, hypertrophic band at a site of deep folliculitis, usually along the posterior hairline of the scalp. It is most commonly seen in men of African descent.


name: protein Z-dependent protease inhibitor N-glycosylated 2 (human)

description: A protein Z-dependent protease inhibitor (human) that has been N-glycosylated at the residue equivalent to Asn-295 of the amino acid sequence represented by UniProtKB:Q9UK55-1, in which the glycan composition is represented by GlyTouCan:G00912UN. Example: UniProtKB:Q9UK55-1, Asn-295, MOD:00160~GNO:G00912UN.


name: protein Z-dependent protease inhibitor, signal peptide removed form (human)

description: A protein Z-dependent protease inhibitor (human) that has had the signal peptide removed. UniProtKB:Q9UK55, 22-444.


name: protein Z-dependent protease inhibitor, signal peptide removed phosphorylated form (human)

description: A protein Z-dependent protease inhibitor (human) that has had the signal peptide removed and that includes at least 1 phosphorylated residue. UniProtKB:Q9UK55, 22-444, MOD:00696.


name: protein Z-dependent protease inhibitor N-glycosylated 1 (human)

description: A protein Z-dependent protease inhibitor (human) that has been N-glycosylated at the residue equivalent to Asn-180 of the amino acid sequence represented by UniProtKB:Q9UK55-1, in which the glycan composition is represented by GlyTouCan:G06247RL. Example: UniProtKB:Q9UK55-1, Asn-180, MOD:00160~GNO:G06247RL.


name: vitamin K-dependent protein C N-glycosylated 32 (human)

description: A vitamin K-dependent protein C (human) that has been N-glycosylated at the residue equivalent to Asn-371 of the amino acid sequence represented by UniProtKB:P04070-1, in which the glycan structure is represented by GlyTouCan:G17409FQ. Example: UniProtKB:P04070-1, Asn-371, MOD:00160~GNO:G17409FQ.


A glyco-amino acid consisting of a D-fructosyl residue attached to the epsilon-amino group of N(alpha)-formyl-L-lysine.


name: adenylate kinase 2, mitochondrial isoform h6 (human)

description: An adenylate kinase 2, mitochondrial (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P54819-6.


name: dedicator of cytokinesis protein 2 methylated 4 (human)

description: A dedicator of cytokinesis protein 2 (human) that has been methylated on the residue at the position equivalent to Lys-61 of the amino acid sequence represented by UniProtKB:Q92608-1. Example: UniProtKB:Q92608-1, Lys-61, MOD:00663.


name: immunoglobulin heavy constant alpha 1 N-glycosylated 13 (human)

description: An immunoglobulin heavy constant alpha 1 (human) that has been N-glycosylated at the residue equivalent to Asn-144 of the amino acid sequence represented by UniProtKB:P01876-2, in which the glycan composition is represented by GlyTouCan:G49955PK. Example: UniProtKB:P01876-2, Asn-144, MOD:00160~GNO:G49955PK.


name: protein mono-ADP-ribosyltransferase PARP4 deaminated 1 (human)

description: A protein mono-ADP-ribosyltransferase PARP4 (human) that has been deaminated on the residue at the position equivalent to Gln-638 of the amino acid sequence represented by UniProtKB:Q9UKK3. UniProtKB:Q9UKK3, Gln-638, MOD:00685.


A protein that is a translation product of the human PARP4 gene or a 1:1 ortholog thereof.