dimethyl azelate

A fatty acid methyl ester that is nonanedioic acid in which both carboxy groups are replaced by methoxycarbonyl groups.


(S)-malaoxon

A diethyl 2-[(dimethoxyphosphoryl)thio]succinate that is the S-enantiomer of malaoxon.


A diester resulting from the formal condensation of the two hydroxy groups of 3-fluorocatechol with the carboxy groups of 3-hydroxybenzoic acid. It is an inhibitor of glucose transporter 1 (GLUT1) that suppresses tumour growth in mouse xenograft models.


meso-doxacurium chloride

The dichloride salt of meso-doxacurium.


(S)-bitolterol mesylate

The methanesulfonate salt of (S)-bitolterol.


(S)-nisoldipine

A methyl 2-methylpropyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate that has S configuration.


(S)-nicardipine

The S-enantiomer of nicardipine.


(S)-malathion

A diethyl 2-[(dimethoxyphosphorothioyl)thio]succinate that is the S-enantiomer of malathion.


diethyl 2-sulfanylbutanedioate

A diester resulting from the formal condensation of the carboxy groups of thiomalic acid with ethanol. It is a metabolite of the insecticide malathion.


A diester resulting from the formal condensation of the carboxylic acid group of beta-D-gentiobiosyl crocetin with the anomeric hydroxy group of beta-D-glucopyranose.


DIETHYL PHTHALATE

The diethyl ester of benzene-1,2-dicarboxylic acid.


(R)-bitolterol mesylate

The methanesulfonate salt of (R)-bitolterol.


butyl butyryllactate

A diester resulting from the formal condensation of the carboxy group of 2-(butanoyloxy)propanoic acid with butan-1-ol.


fumonisin B4

A fumonisin that is fumonisin B2 that is lacking hydroxy group located gamma- to the amino substituent.


(1R,2S,1'R,2'S)-doxacurium chloride

The dichloride salt of (1R,2S,1'R,2'S)-doxacurium.


arabidopside D

An arabidopside that is arabidopside B in which the hydrogen of the hydroxy group at position 6 of the beta-D-galactosyl moiety is replaced by an alpha-D-galactosyl group.


(S)-bitolterol

The (S)-enantiomer of bitolterol.


(R)-nisoldipine

A methyl 2-methylpropyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate that has R configuration.


nemadipine-A

A dihydropyridine that is that is 1,4-dihydropyridine which is substituted at positions 2 and 6 by methyl groups, at positions 3 and 5 by ethoxycarbonyl groups, and at position 4 by a pentafluorophenyl group. An L-type calcium channel alpha1-subunit antagonist. When exposed to the microscopic soil nematode Caenorhabditis elegans, nemadipine-A induces a variety of defects including those affecting morphology and egg laying.


(R)-malaoxon

A diethyl 2-[(dimethoxyphosphoryl)thio]succinate that is the R-enantiomer of malaoxon.


dimethyl sebacate

A fatty acid methyl ester that is sebacic acid  in which both carboxy groups are replaced by methoxycarbonyl groups.


(1S,2R,1'S,2'R)-doxacurium chloride

The dichloride salt of (1S,2R,1'S,2'R)-doxacurium.


(R)-nicardipine

The R-enantiomer of nicardipine.


(R)-bitolterol

The (R)-enantiomer of bitolterol.


name: Clinical Stage IIA Gastroesophageal Junction Adenocarcinoma AJCC v8

category: biolink:Disease biolink:DiseaseOrPhenotypicFeature biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing

description: Stage IIA includes: T1, N1, M0. T1: Tumor invades the lamina propria, muscularis mucosae, or submucosa. N1: Tumor with metastasis in one or two regional lymph nodes. M0: No distant metastasis. (AJCC 8th ed.)


FLUSULFAMIDE

A sulfonamide resulting from the formal condensation 4-chloro-3-(trifluoromethyl)benzenesulfonic acid with 2-chloro-4-nitroaniline. A fungicide, it is used to control Plasmodiophora brassicae in brassicas and Polymyxa betae in sugarbeet.


An N-glycosylated dialkylglycerophosphoethanolamine in which the dialkylglycerophosphoethanolamine is 1,2-dihexadecyl-sn-glycero-3-phosphoethanolamine and the glycosylating saccharide is the branched nonasaccharide alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc, the GlcNAc residue at the reducing end of which is in the ring-opened form.


Ectopic Meningioma

description: A meningothelial neoplasm that arises from an anatomic site outside the intracranial and intraspinal compartments.


Primary Middle Ear Meningioma

description: A rare extracranial meningioma that arises from the middle ear.


Primary Sinonasal Meningioma

description: A rare extracranial meningioma that arises from the sinonasal tract.


manganese(II) sulfate dihydrate

A hydrate that is the dihydrate form of manganese(II) sulfate.


A glycohexaosylceramide having alpha-D-GalNAc-(1->3)-[alpha-L-Fuc-(1->2)]-beta-D-Gal-(1->3)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc as the glycohexaosyl component.


prosolanapyrone II

A prosolanapyrone that is prosolanapyrone I in which one of the hydrogens of the methyl substituent at position 3 of the pyrone ring is substituted by a hydroxy group.


SAICAR

A 1-(phosphoribosyl)imidazolecarboxamide resulting from the formal condesation of the darboxy group of 5-amino-1-(5-O-phosphono-beta-D-ribofuranosyl)-1H-imidazole-4-carboxylic acid with the amino group of L-aspartic acid.


A 1-(phosphoribosyl)imidazolecarboxamide that is the 5-(5-phospho-beta-D-ribosylamino)methylidene derivative of 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide.


A 1-(phosphoribosyl)imidazole that is 5-aminoimidazole in which the proton at position 1 has been replaced by a 5-phospho-beta-D-ribofuranosyl group.


A 1-(phosphoribosyl)imidazole having the phospho group at the 5'-position and a carboxyamino group at the 5-position on the imidazole ring.


name: Hodgkin's disease mixed cellularity stage II subdiaphragmatic


name: Ann Arbor Stage II Mixed Cellularity Classic Hodgkin Lymphoma

description: Ann Arbor Classification: Stage II: Involvement of two or more lymph node regions on the same side of the diaphragm (II); or localized involvement of a single extralymphatic organ or site in association with regional lymph node involvement with or without involvement of other lymph node regions on the same side of the diaphragm (IIE).


name: Hodgkin's disease mixed cellularity stage II supradiaphragmatic


A sialotetraosylceramide consisting of a linear pentasaccharide made up from one lactamized sialyl residue, two galactose residues, one N-acetyl-6-sulfoglucosamine residue and one glucose residue, which at the reducing end is attached to a d18:1/18:0 ceramide moiety via a beta-linkage.


PLATENCIN A4

A polycyclic cage that is the 3-hydroxy derivative of platencin. It is isolated from Streptomyces platensis.


remazole black-GR

A bis(azo) compound with two aryldiazenyl moieties placed at positions 2 and 7 of a multi-substituted naphthalene.


Childhood Sympathetic Paraganglioma

description: A sympathetic paraganglioma that occurs during childhood.


Childhood Paraganglioma

description: A paraganglioma that occurs during childhood.


Childhood Parasympathetic Paraganglioma

description: A parasympathetic paraganglioma that occurs during childhood.


Childhood Composite Paraganglioma

description: A composite paraganglioma that occurs during childhood.


A glycopentaosylceramide having N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucose as the pentasaccharide component.


chromanol

Any member of the class of chromanes that is chromane substituted by one or more hydroxy groups.


A member of the class of chromanols that is (+)-gamma-tocopherol bearing an additional hydroxy substituent at position 13'.


(S,R,S)-alpha-tocopherol

The (S,R,S)-stereoisomer of alpha-tocopherol.


beta-tocotrienol

A tocotrienol that is chroman-6-ol substituted by methyl groups at positions 2, 5 and 8 and a farnesyl chain at position 2. It has been isolated from various cultivars of wheat.


(R,R,S)-alpha-tocopherol

The (R,R,S)-stereoisomer of alpha-tocopherol.


didesmethyl tocotrienol

A tocotrienol that is chroman-6-ol substituted by a farnesyl chain at position 2.


desmethyl tocotrienol

A tocotrienol that is chroman-6-ol substituted by a methyl group at position 2 and a farnesyl group at position 2.


(S,S,R)-alpha-tocopherol

The (S,S,R)-stereoisomer of alpha-tocopherol.


(R,S,R)-alpha-tocopherol

The (R,S,R)-stereoisomer of alpha-tocopherol.


tocol

A chromanol with a chroman-6-ol skeleton that is substituted at position 2 by a saturated or triply-unsaturated hydrocarbon chain consisting of three isoprenoid units.


tocopherol

A collective name for a group of closely related lipids that contain a chroman-6-ol nucleus substituted at position 2 by a methyl group and by a saturated hydrocarbon chain consisting of three isoprenoid units. They are designated as alpha-, beta-, gamma-, and delta-tocopherol depending on the number and position of additional methyl substituents on the aromatic ring. Tocopherols occur in vegetable oils and vegetable oil products, almost exclusively with R,R,R configuration. Tocotrienols differ from tocopherols only in having three double bonds in the hydrocarbon chain.


A member of the class of chromanols that is (+)-alpha-tocopherol bearing an additional hydroxy substituent at position 13'.


beta-tocopherol

A tocopherol in which the chroman-6-ol core is substituted by methyl groups at positions 5 and 8. While it is found in low concentrations in many vegetable oils, only cottonseed oil contains significant amounts.


(S,S,S)-alpha-tocopherol

The (S,S,S)-stereoisomer of alpha-tocopherol.


(S,R,R)-alpha-tocopherol

The (S,R,R)-stereoisomer of alpha-tocopherol.


alpha-tocopherol

A tocopherol that is chroman-6-ol substituted by methyl groups at positions 2, 5, 7 and 8 and a 4,8,12-trimethyltridecyl group at position 2.


(R,S,S)-alpha-tocopherol

The (R,S,S)-stereoisomer of alpha-tocopherol.


arachidonoyl-CoA

An unsaturated fatty acyl-CoA that results from the formal condensation of the thiol group of coenzyme A with the carboxy group of arachidononic acid.


name: Mismatch Repair-Deficient Endometrial Endometrioid Adenocarcinoma

description: An endometrial endometrioid adenocarcinoma characterized by mismatch repair (MMR) deficiency caused by inactivating methylation or less frequently mutation of an MMR gene (MLH1, PMS2, MSH2, or MSH6).


A beta-D-glucosylceramide obtained by formal condensation of the carboxy group of docosanoic acid with the amino group of beta-D-glucosyl-(1<->1')-(4E,14Z)-sphingadienine.


C-14 demethylated eburicol


RIBOSE (PYRANOSE)

A D-ribopyranose with a beta-configuration at the anomeric position.


ribopyranose

The pyranose form of ribose.


L-ribopyranose

The L-stereoisomer of ribopyranose.


beta-L-ribopyranose

A L-ribopyranose with a beta-configuration at the anomeric position.


alpha-L-ribopyranose

A L-ribopyranose with an alpha-configuration at the anomeric position.


D-ribopyranose

A D-ribose and the D-enantiomer of ribopyranose.


alpha-D-ribopyranose

A D-ribopyranose with an alpha-configuration at the anomeric position.


ethyl 3-nonenoate

A fatty acid ethyl ester obtained by the formal condensation of 3-nonenoic acid with ethanol.


A secondary fatty alcohol that is nonadecane substituted by a hydroxy group at position 9.


(4S)-4-hydroxy-4-methyl-L-glutamic acid

A 4-hydroxy-4-methyl-L-glutamic acid that has S-configuration.


Uterine Corpus Neuroendocrine Tumor G1

description: A very rare, well-differentiated, low-grade neuroendocrine neoplasm that arises from the uterine corpus.


Stress ulcer

description: An ulcer due to stress.


Orbit Solitary Fibrous Tumor

description: A solitary fibrous tumor that arises from the orbit. Most of these tumors are benign.


chlorphenesin carbamate

The carbamate ester of the primary hydroxy group of chlorphenesin. A centrally acting skeletal muscle relaxant, it is used in the symptomatic treatment of painful muscle spasm.


A glycopeptidolipid antigen from clinically prominent members of the Mycobacterium avium serocomplex.


Malignant neoplasm of exocervix

description: A malignant neoplasm that affects the exocervix.


CLOTHIANIDINE

A clothiadin that has E configuration at the C=N bond of the nitroguanidine moiety.


thiamethoxam

An oxadiazane that is tetrahydro-N-nitro-4H-1,3,5-oxadiazin-4-imine bearing (2-chloro-1,3-thiazol-5-yl)methyl and methyl substituents at positions 3 and 5 respectively.


omega-hydroxyphylloquinone

A member of the class of phylloquinones obtained by hydroxylation of one of the terminal methyl groups of phylloquinone itself.


A phylloquinone that consists of 1,4-naphthoquinone bearing a phytyl group at position 2.


A carboxamidine heterocycle which is obtained by formal condensation of 4-amino-L-allothreonine with acetic acid.


carboxamidine

Compounds having the structure RC(=NR)NR2. The term is used as a suffix in systematic nomenclature to denote the -C(=NH)NH2 group including its carbon atom.


TRIFLUMIZOLE

A carboxamidine resulting from the formal condensation of the amino group of 4-chloro-2-(trifluoromethyl)aniline with the oxygen of the acetyl group of N-(propoxyacetyl)imidazole. A sterol demethylation inhibitor, it is used as a fungicide for the control of powdery mildew, scab and other diseases on a variety of crops.


An isoquinoline that is 3,4-dihydroisoquinoline bearing amidino and hydroxy substituent at positions 2 and 4 respectively.


A benzamide obtained by formal condensation of the carboxy group of 4-[5-(3,5-dichlorophenyl)-5-(trifluoromethyl)-4,5-dihydro-1,2-oxazol-3-yl]-2-methylbenzoic acid with the amino group of N-methoxymethanimidamide.


(R)-fluxametamide

A 4-[5-(3,5-dichlorophenyl)-5-(trifluoromethyl)-4,5-dihydro-1,2-oxazol-3-yl]-N-[(methoxyamino)methylidene]-2-methylbenzamide that is the (R)-enantiomer of fluxametamide.


A-234 nerve agent

A carboxamidine that is N,N-diethylethanimidamide in which the hydrogen attached to the imino nitrogen has been replaced by a fluoro(ethoxy)phosphoryl group. A toxic nerve agent developed by the former Soviet Union.


A-232 nerve agent

A carboxamidine that is N,N-diethylethanimidamide in which the hydrogen attached to the imino nitrogen has been replaced by a fluoro(methoxy)phosphoryl group. A toxic nerve agent developed by the former Soviet Union.


ACETAMIPRID

The (E)-stereoisomer of acetamiprid.


CYFLUFENAMID

A member of the class of (trifluoromethyl)benzenes that is 2,3-difluoro-6-(trifluoromethyl)benzenecarboxamidine in which the hydrogen attached to the imino nitrogen is replaced by a cyclopropylmethoxy group while one of the hydrogens attached to the other nitrogen is replaced by a phenylacetyl group. It is used as a fungicide for the control of powdery mildew in cereal crops as well as in apple and pear orchards.


A-230 nerve agent

A carboxamidine that is N,N-diethylethanimidamide in which the hydrogen attached to the imino nitrogen has been replaced by a fluoro(methyl)phosphoryl group. A toxic nerve agent developed by the former Soviet Union.


acetamiprid

A carboxamidine that is acetamidine in which the amino hydrogens are substituted by a (6-chloropyridin-3-yl)methyl and a methyl group while the hydrogen attached to the imino nitrogen is replaced by a cyano group.


(S)-fluxametamide

A 4-[5-(3,5-dichlorophenyl)-5-(trifluoromethyl)-4,5-dihydro-1,2-oxazol-3-yl]-N-[(methoxyamino)methylidene]-2-methylbenzamide that is the (S)-enantiomer of fluxametamide.


CARANINE

An indolizidine alkaloid that is  galanthan substituted by analpha-hydroxy group at position 1 and a methylenedioxy group across position 9 and 10. An alkaloid commonly found in the members of the family amaryllidaceae.


yanuthone E

A class I yanuthone that is 22-deacetylyanuthone A in which the primary alcohol has been esterified by condensation with one of the carboxy groups of 3-hydroxy-3-methylglutaric acid.


Genital Human Papillomavirus Infection

description: Infection of the genitalia by human papillomavirus.


A fatty alcohol that is decan-1-ol in which one of the hydrogens at position 9 has been replaced by a methyl group.


Iatrogenic Hypoparathyroidism

description: Hypoparathyroidism resulting from medical treatment or intervention.


Acquired Hypoparathyroidism

description: Hypoparathyroidism, the cause of which is not present at birth.


Hypoparathyroidism, Autosomal Recessive

description: Hypoparathyroidism associated with homozygous mutation(s) in the PTH gene, which encodes parathyroid hormone, or in the GCM2 gene, which encodes chorion-specific transcription factor GCMb.


Transient neonatal hypoparathyroidism

description: A disorder of decreased production of parathyroid hormone by the parathyroid gland in a newborn. It is due to maternal hyperparathyroidism. It may be characterized by hypocalcemic seizures in the first weeks of life.


Primary hypoparathyroidism

description: Abnormally low levels of parathyroid hormone due to a disorder originating within the parathyroid glands.


onium cation

Mononuclear cations derived by addition of a hydron to a mononuclear parent hydride of the pnictogen, chalcogen and halogen families.


A mannosylinositol phosphorylceramide compound having a tetracosanoyl group amide-linked to a C20 phytosphingosine base, with hydroxylation at C-2 and C-3 of the C24 very-long-chain fatty acid.


Circumscribed storiform collagenoma

description: A benign skin tumor characterized as a small, dome-shaped dermal nodule composed of fibroblasts in a dense collagenous background with storiform organization.  Rarely, multiple lesions can occur in connection with Cowden's disease.


Senile nevus

description: A benign skin lesion consisting of a cluster of capillaries at the surface of the skin, forming a red papular lesion.


chlorobenzophenone

A member of the class of benzophenones that is any substituted benzophenone in which at least one of the substituents is a chlorine.


organosilicon compound

An organosilicon compound is a compound containing at least one carbon-silicon bond.


organosiloxane

A siloxane where Si is substituted with organyl groups.


(R)-simeconazole

A 2-(4-fluorophenyl)-1-(1,2,4-triazol-1-yl)-3-(trimethylsilyl)propan-2-ol that is the (R)-enantiomer of simeconazole.


SIMECONAZOLE

A racemate comprising equal amounts of (R)- and (S)-simeconazole. A broad spectrum biofungicide used to control a range of diseases in particular Rhizoctonia solani Kuhn and Blumeria graminis on rice, fruit, soya and vegetables.


(S)-simeconazole

A 2-(4-fluorophenyl)-1-(1,2,4-triazol-1-yl)-3-(trimethylsilyl)propan-2-ol that is the (S)-enantiomer of simeconazole.


SILTHIOFAM

A monocarboxylic acid amide obtained by formal condensation of the carboxy group from 4,5-dimethyl-2-(trimethylsilyl)thiophene-3-carboxlic acid with the amino group of allylamine. A fungicide seed dressing for cereals used mainly to control 'take-all'.


FLUSILAZOLE

An organosilicon compound that is dimethylsilane in which the hydrogens attached to the silicon are replaced by p-fluorophenyl groups and a hydrogen attached to one of the methyl groups is replaced by a 1H-1,2,4-triazol-1-yl group. It is a broad-sepctrum fungicide used to protect a variety of crops.


(S)-triticonazole

A (5E)-5-(4-chlorobenzylidene)-2,2-dimethyl-1-(1,2,4-triazol-1-ylmethyl)cyclopentanol that is the (S)-enantiomer of triticonazole.


OTOSENINE

A pyrrolizine alkaloid that is produced by several Jacobaea and Senecio species.


TRIFOLIN

A beta-D-galactoside compound with a 4',5,7-trihydroxychromen-3-yl group at the anomeric position.


STIGMASTANOL

A 3-hydroxy steroid that is 5alpha-stigmastane which is substituted at the 3beta position by a hydroxy group.


anilines

Any  aromatic amine that is benzene carrying at least one amino substituent and its substituted derivatives.


A member of the class of pyrimidines that is pyrimidine which is substituted at positions 2, 4, and 6 by 2,4-dichloroanilino, trifluoromethyl, and {2-[(1E)-1,3-dimethoxy-3-oxoprop-1-en-2-yl]benzyl}oxy groups, respectively. An acaricide used for the control of mites on citrus and cotton crops.


nitroaniline

A substituted aniline that carries one or more nitro groups.


fluoroaniline

A substituted aniline carrying an additional fluoro substituent on the benzene ring.


(R)-mosapride

A 4-amino-5-chloro-2-ethoxy-N-({4-[(4-fluorophenyl)methyl]morpholin-2-yl}methyl)benzamide that has (R)-configuration.


(R)-aminoglutethimide

The (3R)-enantiomer of aminoglutethimide.


levesquamide

A polyketide-nonribosomal peptide with an isothiazolinone moiety found in Streptomyces sp. RKND-216. It has a strong selective activity against M. tuberculosis, with no cytotoxicity against mammalian cell lines.


A member of the class of quinazolines that is quinazoline which is substituted by a (3-methoxyphenyl)nitrilo group at position 4.


dimethylaniline

A methylaniline carrying at least two methyl groups.


A pyrrolopyrimidine that is 3,5-dihydro-4H-pyrrolo[3,2-d]pyrimidin-4-one substituted by [2-(2,5-difluoroanilino)-2-hydroxyethyl]sulfanediyl, ethyl, and phenyl groups at positions 2, 3, and 7, respectively. It inhibits androgen-induced ROS production.


ZM 323881

A member of the class of quinazolines carrying 2-fluoro-4-methyl-5-hydroxyanilino and benzyloxy substituents at positions 4 and 7 respectively.


monodechloroaminopyrrolnitrin

A member of the class of pyrroles carrying a 2-amino-3-chlorophenyl substituent at position 3.


A member of the class of enamides obtained by formal condensation of the carboxy group of 2-benzamido-3-phenylprop-2-enoic acid with the aromatic amino group of 2-[(4-aminophenyl)sulfanyl]propanoic acid, the carboxy group of which has also undergone formal condensation with the amino group of 5-chloro-2,4-dimethoxyaniline.


A member of the class of quinazolines that is quinazoline which is substituted at positions 2 and 4 by pyridin-4-yl and (3-fluorophenyl)nitrilo groups, respectively.


ASULAM

A carbamate ester that is methyl carbamate substituted by a (4-aminophenyl)sulfonyl group at the nitrogen atom. A dihydropteroate synthase inhibitor, it is used (normally as the corresponding sodium salt, asulam-sodium) as a herbicide, mainly for killing bracken.


anileridine

A piperidinecarboxylate ester that is the ethyl ester of isonipecotic acid in which the hydrogen alpha- to the carboxyl group is substituted by a phenyl group, and the hydrogen attached to the nitrogen is substituted by a 2-(4-aminophenyl)ethyl group.


ACLONIFEN

A primary amino compound that is aniline in which the phenyl group has been substituted at positions 2, 3, and 6 by chlorine, phenoxy, and nitro groups, respectively. A protoporphyrinogen oxidase (PPO) inhibitor, it is used as a herbicide against a broad range of weeds in a wide range of crops.


A member of the class of quinazolines that is quinazoline-2,4-diamine in which one of the hydrogens attached to the amino group at position 2 is replaced by a 3-chloro-4-methylphenyl group. It has been found to stimulate the immune defences of the nematode Caenorhabditis elegans, so affording protection from bacterial infection.


A ribose monophosphate that is 4-(beta-D-ribofuranosyl)aminobenzene carrying a single monophospate substituent at position 5'.


bentioflumin

An aryl sulfide that is benzene substituted by {[2-(methoxycarbonyl)phenyl]methyl}amino, fluoro, chloro, and (2,2,2-trifluoroethyl)sulfanediyl groups at positions 1, 2, 4 and 5, respectively. It is an acaricide discovered by Shandong Kangqiao Bio-technology Co. Ltd that is highly effective against citrus rust mites, red spider mites, and two-spotted spider mites and has excellent leaf penetration properties.


An ethyl ester resulting from the formal condensation of the carboxy group of 3-(benzylamino)-4-(cyclohexylamino)benzoic acid with ethanol. It is a potent inhibitor of ferroptosis induced by erastin in HT-1080 human fibrosarcoma cells (EC50 = 6 nM).


A member of the class of benzamides that is entinostat in which the hydrogen that is para to the nitrogen of the benzamide moiety has been replaced by a fluorine.


A member of the class of pyridopyrimidines that is pyrido[2,3-d]pyrimidine substituted by methylamino, 5-{[(3,3-dimethylbutyl)carbamoyl]amino}-4-fluoro-2-methylphenyl, and methyl groups at positions 2, 6 and 7, respectively. It is a potent pan RAF inhibitor which inhibits BRAF(V600E), BRAF(WT) and CRAF(WT) (IC50 = 5.8, 9.1 and 15 nM, respectively). It also inhibits RAF homo- and heterodimers and exhibits anti-cancer properties.


(S)-aminoglutethimide

The (3R)-enantiomer of aminoglutethimide.


ALLISAN

A nitroaniline that is 4-nitroaniline in which the hydrogens at positions 2 and 6 are replaced by chlorines. An agricultural fungicide, it is not approved for use in the European Union.


methylaniline

A substituted aniline carrying one or more methyl groups at unspecified positions.


A member of the class of purines that is carrying 9-cyclopentyl-9H-purine-2,8-diamine in which the amino groups at positions 2 and 8 are carrying 4-methoxyphenyl and 2-fluorophenyl substituents respectively.


(S)-mosapride

A 4-amino-5-chloro-2-ethoxy-N-({4-[(4-fluorophenyl)methyl]morpholin-2-yl}methyl)benzamide that has (S)-configuration.


An anilide that is N-phenylacetamide substituted by an amino group at position 3 and a chloro group at position 4 respectively.


KYNURENINE

A ketone that is alanine in which one of the methyl hydrogens is substituted by a 2-aminobenzoyl group.


A member of the class of maleimides carrying 3-chloro-4-hydroxyphenylamino and 2-nitrophenyl substituents at positions 3 and 4 respectively.


N,N-dimethylaniline N-oxide

A member of the class of dimethylanilines that is N,N-dimethylaniline in which the tertiary amino group has been oxidised to give the corresponding N-oxide.


aminophenol

A substituted aniline carrying a hydroxy substituent. A 'closed class'.


A secondary carboxamide resulting from the formal condensation of the amino group of (1R,2R)-2-amino-1-(4-aminophenyl)propane-1,3-diol with the carboxy group of dichloroacetic acid. It is an intermediate used in the biosynthesis pathway of the antibiotic, chloramphenicol.


aminopyrrolnitrin

A member of the class of pyrroles carrying chloro and 2-amino-3-chlorophenyl substituents at positions 3 and 4 respectively.


A member of the class of quinazolines that is quinazoline which is substituted at positions 2 and 4 by pyridin-4-yl and (4-methylphenyl)nitrilo groups, respectively.


fluorenes

An ortho-fused polycyclic arene in which the skeleton is composed of two benzene rings ortho-fused to cyclopentane.


A member of the class of  hydroxyfluorenes that is 9H-fluorene substituted by a hydroxy group at position 9 (the non-aromatic carbon).


An ortho-fused polycyclic arene, or derivative thereof, that consists of 9H-fluorene bearing an acetamido substituent at position 2.


Primary Insomnia

description: A sleep disorder characterized by difficulty initiating or maintaining sleep; this difficulty does not occur in the context of another sleep disorder and is not etiologically linked to a mental disorder, substance use, or a general medical condition.


valienone

A member of the class of cyclohexenones that is cyclohex-2-en-1-one substituted by hydroxy groups at positions 4, 5 and 6, and by a hydroxymethyl group at position 3 (the 4R,5S,6R-diastereomer).


tetrol

A polyol that contains 4 hydroxy groups.


A hydroxycalciol that is a synthetic fluorinated and deuterated analogue of vitamin D3 which exhibits vitamin D receptor superagonist and anti-cancer activity.


21-deoxyconcanamycin A

A macrolide antibiotic that is a semisynthetic analogue of concanamycin A, possessing an 18-membered lactone ring and a 6-membered oxane ring in which the hydroxy group at position 23 is glycosylated by a 4-O-carbamoyl-2,6-dideoxy-beta-D-arabino-hexopyranosyl residue.


stemphyloxin I

An octahydronaphthalene that is 2,4,5,7-tetramethyloctahydronaphthalen-1(2H)-one which is substituted by hydroxy groups at positions 2 and 7, a (2R)-1-hydroxybutan-2-yl group at position 3, and a (2Z)-3-hydroxyprop-2-enoyl group at position 4 (the 2S,3R,4R,4aS,5R,7R,8aS stereoisomer). Isolated from the endophytic fungus Stemphylium botryosum, it is the causal agent of leaf spot and foliage blight disease in tomatoes. Its phytotoxcity is at least 200 times greater than that of stemphyloxin II. It shows high affinity for Fe(3+) (but not Fe(2+)) ions.


oligomycin C

An oligomycin with formula C45H74O10 that is oligomycin A in which the hydroxy group that is alpha- to a macrolide keto group has been replaced by a hydrogen. It is an inhibitor of the mitochondrial F1F0 ATP synthase.


pavettamine

An aminoalcohol that is N(1)-(5-aminopentyl)pentane-1,5-diamine substituted by hydroxy groups at positions 2, 2', 4 and 4' (the 2R,4S,2'R,4'S-stereoisomer). It is a toxin produced by several plant species and the casual agent of gousiekte (''quick'' disease).


1alpha,23(S),25-trihydroxyvitamin D3

A hydroxycalciol that consists of vitamin D3 (calciol) bearing additional hydroxy substituents at positions 1, 23 and 25 (with 1alpha,23S-configuration). An intermediate in the degradation pathway of 1alpha,25-(OH)2D3.


(20S,23,24)-trihydroxyvitamin D3

A hydroxycalciol that consists of vitamin D3 (calciol) carrying additional hydroxy groups  at positions 20 (with S-configuration), 23 and 24.


cryptocaryol B

A member of the class of 2-pyranones that is 5,6-dihydro-2H-pyran-2-one substituted by a 10-(acetyloxy)-2,4,6,8-tetrahydroxypentacosyl group at position 6.It has been isolated from Cryptocarya species.


A vitamin D that is 19-norcalcitriol carrying an additional 3-hydroxypropyl substituent at position 2. A synthetic analogue of vitamin D, it exhibits anticancer properties.


A member of the class of cyclohexenones that is 5-(hydroxymethyl)cyclohex-2-en-1-one carrying three additional hydroxy substituents at positions 2, 3 and 5.


ent-pavettamine

An aminoalcohol that is N(1)-(5-aminopentyl)pentane-1,5-diamine substituted by hydroxy groups at positions 2, 2', 4 and 4' (the 2R,4S,2'R,4'S-stereoisomer).


dihydrostemphyloxin I

An octahydronaphthalene that is stemphyloxin I in which the C=C bond of the enol moiety has been reduced to a C-C bond.


sceliphrolactam

A polyene macrocyclic lactam with formula C28H35NO6. It was isolated from an actinomycete, Streptomyces sp. and displays antifungal activity against amphotericin B-resistant Candida albicans.


gigantetronenin

A member of the class of oxolanes that is tetrahydrofuran substituted by a  6-hydroxy-7-(5-methyl-2-oxo-2,5-dihydrofuran-3-yl)heptyl group at position 2 and a (8Z)-1,4,5-trihydroxyhenicos-8-en-1-yl group at position 5. Isolated from Goniothalamus giganteus, it exhibits cytotoxic activity.


eucommiol

An alicyclic compound that is cyclopent-3-en-1-ol carrying additional hydroxymethyl substituents at positions 3 and 4 as well as a 2-hydroxyethyl substituent at position 2 (the 1R,2R-diastereomer).


(20S,23,25)-trihydroxyvitamin D3

A hydroxycalciol that consists of vitamin D3 (calciol) carrying additional hydroxy groups at positions 20 (with S-configuration), 23 and 25.


A hydroxycalciol that is calcitriol with a 4-hydroxybutoxy group at position 2.


A phosphatidylcholine 24:0 in which the acyl groups specified at positions 1 and 2 are tetradecanoyl and decanoyl respectively.


Cor triloculare

description: A congenital anatomic anomaly in which the heart has only three chambers.


name: Splenic Manifestation of Chronic Lymphocytic Leukemia

description: Infiltration of the spleen by chronic lymphocytic leukemia. It primarily involves the white pulp.


CYSTODYTIN G

An alkaloid that is an enamide obtained by the formal condensation of tiglic acid with 6-(2-amino-1-methoxyethyl)-4H-pyrido[2,3,4-kl]acridin-4-one. It is isolated from the Okinawan marine tunicate Cystodytes dellechiajei and exhibits cytotoxicity against human epidermoid carcinoma KB cells


A 6-lactoyl-5,6,7,8-tetrahydropterin in which the stereocentre at position 6 has R-configuration.


Kaposi's sarcoma of oral cavity

description: Kaposi sarcoma arising from the oral cavity.


deisopropylatrazine

A diamino-1,3,5-triazine that is N-ethyl-1,3,5-triazine-2,4-diamine substituted by a chloro group at position 6.


Parotid Gland Lipoma

description: A lipoma that arises from the parotid gland.


diazine

The parent structure of the diazines.


An  oxazolidinone that is 1,3-oxazolidine with an oxo substituent at position 2.


A 2,3-diacyl-1-alpha-D-galactosyl-sn-glycerol in which the groups at the 2- and 3-positions are oleoyl and palmitoyl respectively.


ethyl phenylcyanoacetate

An alpha-substituted cyanoacetate ester that consists of ethyl cyanoacetate bearing an alpha-phenyl substituent.


A 1-alkyl-2-acyl-sn-glycero-3-phosphate in which the alkyl and acyl groups are specified as palmityl (hexadecyl) and oleoyl respectively.


A glycerophosphoethanolamine that is sn-glycero-3-phosphoethanolamine in which positions 1 and 2 are substituted by unspecified acyl and alkyl groups, and in which the positions of the acyl and alkyl groups are also unspecified.


phosphatidylethanolamine O-37:1

An alkyl,acyl-sn-glycero-3-phosphoethanolamine in which the alkyl or acyl groups at positions 1 and 2 contain a total of 37 carbons and 1 double bond.


An alkyl,acyl-sn-glycero-3-phosphoethanolamine in which unspecified alkyl and acyl groups are located at positions 1 and 2 respectively.


A 1-alkyl-2-acyl-sn-glycero-3-phosphoethanolamine in which the alkyl and the acyl groups at positions 1 and 2 are specified as eicosyl and linolenyl respectively.


phosphatidylethanolamine O-39:5

An alkyl,acyl-sn-glycero-3-phosphoethanolamine in which the alkyl or acyl groups at positions 1 and 2 contain a total of 39 carbons and 5 double bonds.


An alkyl,acyl-sn-glycero-3-phosphoethanolamine in which unspecified acyl and alkyl groups are located at positions 1 and 2 respectively.


A 2-acyl-1-alkyl-sn-glycero-3-phosphoethanolamine in which the alkyl and the acyl groups at positions 1 and 2 are specified as hexadecyl and acetyl respectively.


azulenes

Any carbobicyclic compound whose skeleton consists of a cyclopentane ring ortho-fused to a cycloheptane ring.


beta-D-quinovofuranose

A D-quinovose (6-deoxy-D-glucose) that is D-quinovofuranose in which the anomeric centre has beta configuration.


tin dioxide

A tin oxide compound consisting of tin(IV) covalently bound to two oxygen atoms.


tin oxide

A metal oxide containing tin and oxygen.


phytanoyl-CoA

The S-phytanoyl derivative of coenzyme A.


manganese(II) sulfate hexahydrate

A hydrate that is the hexahydrate form of manganese(II) sulfate.


name: Ann Arbor Stage I Lymphocyte-Depleted Classic Hodgkin Lymphoma

description: Ann Arbor Classification: Stage I: Involvement of a single lymph node region (I); or localized involvement of a single extralymphatic organ or site in the absence of any lymph node involvement (IE) (rare in Hodgkin lymphoma).


name: Ann Arbor Stage I Supradiaphragmatic Lymphocyte-Depleted Classic Hodgkin Lymphoma


name: Ann Arbor Stage I Subdiaphragmatic Lymphocyte-Depleted Classic Hodgkin Lymphoma


A triacyl-sn-glycerol in which the 1-acyl group is octadecanoyl while the 2- and 3-acyl groups are oleoyl.


Diaper Rash

description: An inflammatory skin condition in the diaper area that may be caused by irritation or infection.


Diaper candidiasis

description: An inflammatory skin condition in the diaper area superimposed with Candida infection, characterized by a bright red rash with a sharply demarcated edge and satellite lesions. Skin folds are often involved.


name: Stage IB Adult Soft Tissue Sarcoma AJCC v7


name: 4-(2-phenylethylsulfamoyl)-1H-pyrrole-2-carboxylic acid methyl ester


compound E

An L-alanine derivative that is the amide obtained by formal condensation of the carboxy group of N-[(3,5-difluorophenyl)acetyl]-L-alanine with the amino group of (3S)-3-amino-1-methyl-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one. An inhibitor of memapsin 2 (gamma-secretase).


Congenital anomaly of tricuspid valve

description: A defect of the tricuspid valve present at birth.


(KDO)2-(palmitoleoyl)-lipid IVA

A lipid A comprising lipid IVA glycosylated with two 3-deoxy-D-manno-octulosonic acid (KDO) residues and carrying an additional palmitoleoyl group.


Midgut Neuroendocrine Tumor G1

description: A neuroendocrine tumor grade 1 that arises from the jejunum, ileum, proximal colon, or appendix.


name: Metastatic Midgut Neuroendocrine Tumor G1

description: A midgut neuroendocrine tumor G1 that has spread from its original site of growth to another anatomic site.


A methyl-branched fatty acyl-CoA obtained from the formal condensation of the thiol group of coenzyme A with the carboxy group of (E)-isoheptadec-2-enoic acid.


name: Locally Advanced Digestive System Neuroendocrine Tumor G3

description: Digestive system neuroendocrine tumor G3 that has spread from its original site of growth to nearby tissues or lymph nodes.


name: Psoralen and long-wave ultraviolet radiation (PUVA) keratosis

description: A hyperkeratotic skin lesion that occurs in patients with a history of prolonged exposure to psoralen and ultraviolet A (PUVA) therapy.


A medium-chain primary fatty alcohol that is dodecane carrying hydroxy groups at positions 1 and 11.


An unsaturated fatty acyl-CoA that results from the formal condensation of the thiol group of coenzyme A with the carboxy group of cis-dec-4-enoic acid.


L-mannitol

The L-enantiomer of mannitol.


A methyl-branched fatty acyl-CoA obtained from the formal condensation of the thiol group of coenzyme A with the carboxy group of 3-hydroxyisopentadecanoic acid.


Oral Cavity Mucosal Melanoma

description: A rare melanoma that arises from the oral cavity. It is associated with a poor prognosis.


A racemate comprising an equimolar mixture of the two stereoisomers of 4-dodecyl-2,5-dimethylmorpholine in which the methyl substituents are in a trans relationship to each other.


Childhood Posterior Fossa Ependymoma

description: A posterior fossa ependymoma that occurs during childhood.


double-walled carbon nanotube

A carbon nanotube consisting of two concentric graphene cylinders.


multi-walled carbon nanotube

A molecule consisting of three or more concentric graphene cylinders.


carbon nanorope

A carbon nanostructure consisting of carbon nanotubes which have been spun or bundled together.


zigzag carbon nanotube

A single walled carbon nanotube with (n,m) indices equal to (n,0) or (0,m). Zigzag carbon nanotubes have a chiral angle of 0degree and can be either metallic or semiconducting.


carbon nanofibre

A carbon nanostructure consisting of layers of stacked graphite cones or plates.


carbon nanohorn

A single-walled carbon nanostructure with an irregular horn-like shape.


armchair carbon nanotube

A single-walled carbon nanotube with equal n and m indices. Armchair carbon nanotubes have a chiral angle of 30degree and are metallic.


carbon black nanoparticle

Any form of carbon black which has a particle size of less than 100 nm in each dimension.


metallic single-walled carbon nanotube

A single-walled carbon nanotube with (n,m) indices such that n-m is a multiple of 3.


chiral carbon nanotube

A single-walled carbon nanotube with unequal (n,m) indices and a chiral angle of between 0 and 30degree.


single-walled carbon nanotube

A carbon nanotube consisting of a single graphene cylinder. Different kinds of single-walled carbon nanotube are distinguished by the indices (n,m) which describe the vector along which the graphene is rolled. The chiral angle is the angle between the vector and the origin and can take any value between 0 and 30degree.


name: semiconducting single-walled carbon nanotube

description: A single-walled carbon nanotube with (n,m) indices such that n-m is not a multiple of 3.


carbon nanotube

A molecule consisting of a graphene cylinder or two or more concentric graphene cylinders.


NAPROPAMIDE

A racemate composed of equimolar amounts of (S)- and (R)-napropamide.


vanilloyl-CoA

A member of the class of benzoyl-CoAs having 4-hydroxy-3-methoxybenzoyl (also known as vanilloyl) as the aroyl group. A potential intermediate of vanillate biosynthesis.


Adult Benign Brain Stem Neoplasm

description: A benign neoplasm of the brain stem occurring in adults.


Medullary Hemangioblastoma

description: A hemangioblastoma that arises from the medulla oblongata.


Childhood Brain Stem Gliosarcoma

description: A gliosarcoma that arises from the brain stem and occurs during childhood.


Childhood Brain Stem Mixed Glioma

description: A mixed glioma that arises from the brain stem and occurs during childhood.


name: Metastatic malignant neoplasm to brain stem

description: A malignant neoplasm that has spread from its original site of growth to the brain stem.


Recurrent Childhood Brain Stem Glioma

description: The reemergence of brain stem glioma in childhood after a period of remission.


Anaplastic Brain Stem Astrocytoma

description: An anaplastic astrocytoma that arises from the brain stem.


Brain Stem Glioblastoma

description: A glioblastoma that arises from the brain stem.


Anaplastic Brain Stem Glioma

description: An anaplastic glioma that arises from the brain stem.


Recurrent Acute Bilineal Leukemia

description: The reemergence of acute bilineal leukemia after a period of remission.


name: Recurrent Mixed Phenotype Acute Leukemia

description: The reemergence of mixed phenotype acute leukemia after a period of remission.


acute biphenotypic leukemia in relapse

description: The reemergence of acute biphenotypic leukemia after a period of remission.


An N-acyl-15-methylhexadecasphing-4-enine-1-phosphocholine in which the acyl group has 21 carbons and 1 double bond.


PHENTHOATE

An organic thiophosphate that is  ethyl mandelate in which the hydroxy group has been replaced by a (dimethoxyphosphorothioyl)sulfanediyl group.


name: Ampulla of Vater Neuroendocrine Tumor G3

description: A well differentiated, high grade neoplasm with neuroendocrine differentiation that arises from the ampulla of Vater and the periampullary region. The Ki-67 index is higher than 20%.


A glucosylglycerol phosphate consisting of sn-glycerol 3-phosphate having a beta-D-glucosyl residue attached at position 2.


A glycohexaosylceramide having beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc as the glycohexaosyl component.


name: Pancreatic Intraductal Papillary Mucinous Neoplasm, Pancreatobiliary-Type

description: A pancreatic intraductal papillary mucinous neoplasm characterized by the presence of neoplastic epithelial cells that form thin-branching papillae and exhibit high grade dysplasia.


name: Pancreatic Intraductal Papillary Mucinous Neoplasm, Gastric-Type

description: A pancreatic intraductal papillary mucinous neoplasm characterized by the presence of neoplastic epithelial cells that are similar to gastric foveolar epithelial cells.


name: Branch Duct Pancreatic Intraductal Papillary-Mucinous Neoplasm

description: An intraductal papillary-mucinous neoplasm of the pancreas that arises in one of the branches of the main pancreatic duct.  It usually has an indolent behavior.


name: Mixed Type Pancreatic Intraductal Papillary-Mucinous Neoplasm

description: An intraductal papillary-mucinous neoplasm of the pancreas that arises primarily from the main pancreatic duct and extends to the branch ducts.


name: Pancreatic Intraductal Papillary Mucinous Neoplasm, Oncocytic-Type

description: A pancreatic intraductal papillary mucinous neoplasm characterized by the presence of neoplastic epithelial cells with abundant eosinophilic granular cytoplasm.


name: Main Duct Pancreatic Intraductal Papillary-Mucinous Neoplasm

description: An intraductal papillary-mucinous neoplasm of the pancreas that arises from the main pancreatic duct.


name: Pancreatic Intraductal Papillary Mucinous Neoplasm, Intestinal-Type

description: A pancreatic intraductal papillary mucinous neoplasm characterized by the presence of neoplastic epithelial cells that form tall papillae, similar to those that are present in colonic villous adenomas.


Advanced Rhabdoid Tumor

description: Rhabdoid tumor that has spread extensively to other anatomic sites or is no longer responding to treatment.


Metastatic Rhabdoid Tumor

description: A rhabdoid tumor that has spread from the original site of growth to another anatomic site.


name: sialadenoma papilliferum of salivary gland

description: An uncommon exophytic papillary proliferation that involves mucosal surface epithelium and salivary duct epithelium. It is exceptional among salivary gland neoplasms because it manifests as an exophytic papillary excrescence of the mucosa, rather than as a submucosal or intraglandular mass. It most often affects the hard or soft palate.  It is generally asymptomatic.


AURACHIN B

An A-type aurachin that is quinoline N-oxide which is substituted by a methyl group at position 2, a hydroxy group at position 3, and a triprenyl group at position 4.


AURACHIN C

A C-type aurachin that is quinolin-4-one which is substituted by a hydroxy group at positions 1, a methyl group at position 2, and a triprenyl group at position 3.


A phosphine oxide in which the substituents on phosphorus are 4-carboxybut-1-yn-1-yl, methyl and 2-methoxyphenyl.


name: Low Grade Malignant Peripheral Nerve Sheath Tumor

description: A malignant peripheral nerve sheath tumor that is low-grade.


A glycophytoceramide having an alpha-D-galactopyranosyl residue at the O-1 position and a tetracosanoyl group attached to the nitrogen.


Tentorial Tear Related to Birth

category: biolink:PhenotypicFeature biolink:DiseaseOrPhenotypicFeature biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing

description: Disruption of the tentorium cerebelli incurred during delivery.


A beta-D-glucosyl-N-acylsphingosine in which the acyl group is specified as tetracosanoyl.


name: Classic Hydroa Vacciniforme Lymphoproliferative Disorder

description: Hydroa vacciniforme lymphoproliferative disorder characterized by the presence of self-limited papulovesicular skin lesions in sun-exposed areas. There is no involvement of internal organs. It has an indolent course and usually affects White individuals.


A polyunsaturated fatty aldehyde that is (2E,6E,8E,10E)-dodeca-2,6,8,10-tetraenal in which the pro-S hydrogen at position 5 has been replaced by a hydroxy group.


Stage II Childhood Hodgkin Lymphoma

description: Ann Arbor Classification: Stage II: Involvement of two or more lymph node regions on the same side of the diaphragm (II); or localized involvement of a single extralymphatic organ or site in association with regional lymph node involvement with or without involvement of other lymph node regions on the same side of the diaphragm (IIE).


trans-(S)-nicotine N(1')-oxide

An (S)-nicotine N(1')-oxide in which the N(1')-methyl group is on the opposite side of the pyrrolidine ring to the pyridine substituent. The major species at pH 7.3.


pyrrolidine N-oxides

Any member of the class of pyrrolidines that are substituted by an organyl group at position 1 and in which the amino group of the pyrrolidine ring has been oxidised to give the corresponding N-oxide.


nicotine N(1')-oxide

A tertiary amine oxide resulting from the oxidation of the pyrrolidine nitrogen of nicotine.


(S)-nicotine N(1')-oxide

A nicotine N(1')-oxide resulting from the oxidation of the pyrrolidine nitrogen of (S)-nicotine; major species at pH 7.3.


cis-(S)-nicotine N(1')-oxide

An (S)-nicotine N(1')-oxide in which the N(1')-methyl group is on the same side of the pyrrolidine ring as the pyridine substituent. The major species at pH 7.3.


Carsickness

description: A sensation of discomfort associated with ground travel; symptoms may include nausea, vomiting, dizziness or sweating.


name: Refractory Paranasal Sinus Squamous Cell Carcinoma

description: Paranasal sinus squamous cell carcinoma that does not respond to treatment.


name: Refractory Head and Neck Squamous Cell Carcinoma

description: A head and neck squamous cell carcinoma that does not respond to treatment.


name: Refractory Sinonasal Squamous Cell Carcinoma

description: Nasal cavity and paranasal sinus squamous cell carcinoma that does not respond to treatment.


name: Refractory Oral Cavity Squamous Cell Carcinoma

description: Oral cavity squamous cell carcinoma that does not respond to treatment.


name: Refractory Cutaneous Squamous Cell Carcinoma of the Head and Neck

description: Cutaneous squamous cell carcinoma of the head and neck that does not respond to treatment.


Hodgkin's lymphoma of small intestine

description: A Hodgkin lymphoma that arises from the small intestine.


name: Resectable Pancreatic Acinar Cell Carcinoma

description: Pancreatic acinar cell carcinoma that is amenable to surgical resection.


Pancreas carcinoma resectable

description: Carcinoma of the pancreas amenable to surgical removal.


name: Borderline Resectable Pancreatic Ductal Adenocarcinoma

description: A pancreatic ductal adenocarcinoma term that refers to a continuum between resectable and locally advanced unresectable disease.


Pancreatic adenocarcinoma resectable

description: Pancreatic adenocarcinoma that is amenable to surgical resection.


name: Resectable Pancreatic Ductal Adenocarcinoma

description: Pancreatic ductal adenocarcinoma amenable to surgical resection.


name: Resectable Pancreatic Adenosquamous Carcinoma

description: Pancreatic adenosquamous carcinoma that is amenable to surgical resection.


A tetrahydromethanopterin having a methanylylidene joined to the nitrogens at the 5- and 10-positions.


A fatty alcohol 20:1 that is icosanol containing a double bond located at position 11 (the 11Z-geoisomer).


A ceramide phosphoinositol compound having a tetracosanoyl group amide-linked to a C20 phytosphingosine base, with hydroxylation at C-2 of the C24 very-long-chain fatty acid.


name: Stage I Lip and Oral Cavity Cancer AJCC v8

description: Stage I includes: T1, N0, M0.  T1: Tumor size 2 cm or less in greatest dimension and 5 mm or less depth of invasion (DOI).  N0: No regional lymph node metastasis.  M0: No distant metastasis. (AJCC 8th Ed.)


Brain Pilocytic Astrocytoma

description: Pilocytic astrocytoma that arises from the brain.


Third Ventricle Pilocytic Astrocytoma

description: A pilocytic astrocytoma occurring in the third ventricle.


name: 2-[(5-chloro-2-thiophenyl)-oxomethyl]imino-3,4-dimethyl-5-thiazolecarboxylic acid ethyl ester


name: Hemolytic anemia due to disseminated intravascular coagulation


Anemia due to membrane defect

description: A group of inherited hemolytic anemias caused by erythrocyte membrane defects. This includes hereditary pyropoikilocytosis, hereditary spherocytosis and hereditary elliptocytosis.


Immune Hemolytic Anemia

description: An acquired anemia resulting from immune-mediated destruction of the red blood cells. Causes include autoimmune disorders, blood transfusions, and drugs.


Anemia, Hemolytic, Acquired

description: Hemolytic anemia, the cause of which is not present at birth.


Infantile pyknocytosis

description: A rare, neonatal syndrome characterized by early jaundice that becomes rapidly associated with severe hemolytic anemia. The peripheral blood smear is remarkable for small irregular, contracted red blood cells with hyper-dense spikes (pyknocytes), that progressively increase in number and then spontaneously disappear.


Refractory Lymphomatoid Granulomatosis

description: Lymphomatoid granulomatosis that is resistant to treatment.


name: Angiocentric immunoproliferative lesion grade 2

description: Lymphomatoid granulomatosis characterized by the presence of occasional large lymphoid cells or immunoblasts in a polymorphous background. Necrosis is more commonly seen as compared to grade I lymphomatoid granulomatosis. By in situ hybridization, EBV-positive cells are readily seen.


name: Central Nervous System Lymphomatoid Granulomatosis

description: Lymphomatoid granulomatosis that affects the brain, spinal cord, and leptomeninges.


Cutaneous Lymphomatoid Granulomatosis

description: Lymphomatoid granulomatosis that affects the skin.


Childhood Lymphomatoid Granulomatosis

description: Lymphomatoid granulomatosis that occurs during childhood.


CINANSERIN HYDROCHLORIDE

The hydrochloride salt of cinanserin. It is an inhibitor of 3C-like proteinase of severe acute respiratory syndrome coronavirus (SARS-Cov) and reduces virus replication in vitro.


5-fluorouridine 5'-monophosphate

A pyrimidine ribonucleoside 5'-monophosphate having 5-fluorouracil as the pyrimidine component.


name: High Grade Anal Canal Intraepithelial Neoplasia

description: Intraepithelial neoplasia involving the anal canal.  The epithelial cells exhibit moderate dysplasia (grade II intraepithelial neoplasia) or severe dysplasia (grade III intraepithelial neoplasia or carcinoma in situ).


MULTIPLOLIDE B

A 10-membered lactone obtained from 10-methyl-9,10-dihydro-2H-oxecin-2-one by the epoxidation of the double bond at position 3-4 and cis-dihydroxylation of the double bond at position 7-8, with further acylation of the hydroxy group at position 8 by a but-2-enoyl group. Multiplolide B was first isolated from the fungus Xylaria multiplex BCC 1111. It shows antifungal activity against Candida albicans. The epoxide group has cis-configuration, but its configuration relative to the other substituents was not established.


DEAMINOHYDROXYVALINE

The R-enantiomer of 2-hydroxy-3-methylbutyric acid.


benzoin

A ketone that consists of acetophenone bearing hydroxy and phenyl substituents at the alpha-position. The parent of the class of benzoins.


A member of the class of pterocarpans that is (6aS,11aS)-3,6a,9-trihydroxypterocarpan in which the hydrogen atom at position 2 is substituted by a 3-methylbut-2-en-1-yl group.


hederacine B

An alkaloid isolated from Glechoma hederaceae.


D-tagatose

The D-enantiomer of tagatose.


carbonate ester

Any carbonate that is carbonic acid in which the hydrogens have been replaced by organyl groups.


(R)-tolpyralate

A 1-({1-ethyl-4-[3-(2-methoxyethoxy)-2-methyl-4-(methylsulfonyl)benzoyl]-1H-pyrazol-5-yl}oxy)ethyl methyl carbonate that has R-configuration.


(S)-tolpyralate

A 1-({1-ethyl-4-[3-(2-methoxyethoxy)-2-methyl-4-(methylsulfonyl)benzoyl]-1H-pyrazol-5-yl}oxy)ethyl methyl carbonate that has S-configuration.


A benzoylpyrazole that is 1H-pyrazole substituted by an ethyl, 3-(2-methoxyethoxy)-2-methyl-4-(methylsulfonyl)benzoyl, and 1-[(methoxycarbonyl)oxy]ethoxy groups at positions 1, 4 and 5, respectively.


SPIROTETRAMAT

An azaspiro compound that is methoxycyclohexane which is fused at position 4 to the 5-position of a 1,5-dihydro-2H-pyrrol-2-one that is substituted at positions 3 and 4 by 2,5-dimethylphenyl and (ethoxycarbonyl)oxy groups, respectively (the cis isomer). It is a proinsecticide (via hydrolysis of the ethyl carbonate group to give the corresponding 4-hydroxypyrrol-2-one, "spirotetramat-enol") and is used for the control of a wide range of sucking insects on fruit and potato crops.


spiropidion

An azaspiro compound that is 1-methoxypiperidine which is fused at position 4 to the 5-position of a 1,5-dihydro-2H-pyrrol-2-one that is substituted at positions 1, 3 and 4 by methyl, 4-chloro-2,6-dimethylphenyl and (ethoxycarbonyl)oxy groups, respectively. It is a proinsecticide developed by Syngenta and used to protect a wide range of crops from some of the most damaging, difficult to control sucking pests such as aphids, whiteflies, Pysllids, armoured scales, soft scales, spider mites, rust mites, and red mites including California red scale, green peach aphid (Myzus persicae), tobacco whitefly etc.


spirobudifen

An oxaspiro compound that is 1-oxaspiro[4.5]dec-3-en-2-one substituted by 2,4-dichlorophenyl and (butoxycarbonyl)oxy groups at positions 3 and 4, respectively. It is an acaricide from Zhejiang Udragon Bioscience.


(S)-salmeterol

2-(Hydroxymethyl)-4-(1-hydroxy-2-{[6-(4-phenylbutoxy)hexyl]amino}ethyl)phenol in which the stereocentre has S configuration.


(R)-salmeterol

2-(Hydroxymethyl)-4-(1-hydroxy-2-{[6-(4-phenylbutoxy)hexyl]amino}ethyl)phenol in which the stereocentre has R configuration.


Refractory Neuroblastoma

description: A neuroblastoma that does not respond to treatment.


lysidine monophosphate

A pyrimidine ribonucleoside 5'-monophosphate that is CMP in which the 2-keto group on the cytosine ring is replaced by an epsilon-L-lysyl residue.


name: Reactive Hyperplasia of the Retinal Pigment Epithelium

description: A reactive, non-neoplastic hyperplasia of the retinal pigment epithelium.


22-hydroxydocosanoic acid

An omega-hydroxy-long-chain fatty acid obtained by monohydroxylation of the terminal methyl group of docosanoic acid.


carbohydroximic acid

A carboximidic acid having an OH or OR (R = organyl) group attached to the imide nitrogen.


boron-10 atom

A stable isotope of boron with relative atomic mass 10.0129370, 19.9 atom percent natural abundance and nuclear spin 3+.


An ascarosyloxycarboxylic acid beta-D-glucopyranosyl ester resulting from the formal esterification of the carboxy group of ascr#20 with the anomeric hydroxy group of beta-D-glucopyranose. It is a metabolite of the nematode Caenorhabditis elegans.


An ascarosyloxycarboxylic acid beta-D-glucopyranosyl ester resulting from the formal esterification of the carboxy group of ascr#22 with the anomeric hydroxy group of beta-D-glucopyranose. It is a metabolite of the nematode Caenorhabditis elegans.


An ascarosyloxycarboxylic acid beta-D-glucopyranosyl ester resulting from the formal esterification of the carboxy group of ascr#24 with the anomeric hydroxy group of beta-D-glucopyranose. It is a metabolite of the nematode Caenorhabditis elegans.


An ascarosyloxycarboxylic acid beta-D-glucopyranosyl ester resulting from the formal esterification of the carboxy group of ascr#1 with the anomeric hydroxy group of beta-D-glucopyranose. It is a metabolite of the nematode Caenorhabditis elegans.


An ascarosyloxycarboxylic acid beta-D-glucopyranosyl ester resulting from the formal esterification of the carboxy group of ascr#10 with the anomeric hydroxy group of beta-D-glucopyranose. It is a metabolite of the nematode Caenorhabditis elegans.


An ascarosyloxycarboxylic acid beta-D-glucopyranosyl ester resulting from the formal esterification of the carboxy group of ascr#3 with the anomeric hydroxy group of beta-D-glucopyranose. It is a metabolite of the nematode Caenorhabditis elegans.


An ascarosyloxycarboxylic acid beta-D-glucopyranosyl ester resulting from the formal esterification of the carboxy group of ascr#16 with the anomeric hydroxy group of beta-D-glucopyranose. It is a metabolite of the nematode Caenorhabditis elegans.


An ascarosyloxycarboxylic acid beta-D-glucopyranosyl ester resulting from the formal esterification of the carboxy group of ascr#26 with the anomeric hydroxy group of beta-D-glucopyranose. It is a metabolite of the nematode Caenorhabditis elegans.


An ascarosyloxycarboxylic acid beta-D-glucopyranosyl ester resulting from the formal esterification of the carboxy group of ascr#18 with the anomeric hydroxy group of beta-D-glucopyranose. It is a metabolite of the nematode Caenorhabditis elegans.


BUTYROLACTONE I

The prenylated form of butyrolactone II; major microspecies at pH 7.3


ethyl N-acetylneuraminate

The carboxylic ester that is the ethyl ester of N-acetylneuraminic acid.


Ins-1-P-Cer B/B'

An inositol phosphoceramide in which either the acyl group is hydroxylated at position 2 or the ceramide base is hydroxylated at position 4.


beta-D-fructofuranose 6-phosphate

A D-fructofuranose 6-phosphate with a beta-configuration at the anomeric position.


D-fructofuranose 6-phosphate

The five-membered ring form of D-fructose 6-phosphate.


(R)-myclobutanil

A 2-(4-chlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)hexanenitrile that has R configuration.


beta-aminoarteether

An artemisinin derivative in which the lactone of (+)-artemisinin has been converted into the corresponding lactol 2-aminoethyl ether [beta (S) configuration at the new stereocentre].


A sphingomyelin 41:2 obtained by formal condensation of the carboxy group of tricosanoic acid with the amino group of any sphingadienine-1-phosphocholine.


N-triacontanoylsphinganine

A dihydroceramide in which the ceramide N-acyl group is specified as tricontanoyl.


Non-toxic multinodular goiter

description: A multinodular goiter that is not associated with changes in thyroid function or malignancy.


Multinodular Endemic Goiter

description: A multinodular goiter caused by inadequate iodine intake.


2-phenylethyl pentanoate

A fatty acid ester obtained by the formal condensation of 2-phenylethanol with  valeric acid.


Adult Leiomyosarcoma

description: An aggressive malignant smooth muscle neoplasm, occurring in adults.  It is characterized by a proliferation of neoplastic spindle cells.


Penile Leiomyosarcoma

description: A leiomyosarcoma that occurs in the penis.


Unresectable Leiomyosarcoma

description: A leiomyosarcoma which is not amenable to surgical resection.


Dedifferentiated Leiomyosarcoma

description: A pleomorphic leiomyosarcoma that lacks immunohistochemical staining for myogenic markers in the pleomorphic areas.


name: Stage IVB Uterine Corpus Leiomyosarcoma AJCC v8

description: Stage IVB includes: Any T, Any N, M1. M1: M1: Distant metastasis (excluding adnexa, pelvic, and abdominal tissues). (from AJCC 8th Ed.)


Pancreatic Leiomyosarcoma

description: A rare leiomyosarcoma that arises from the pancreas.


Head and Neck Leiomyosarcoma

description: A malignant neoplasm with smooth muscle differentiation that arises from the head and neck. The most frequently affected sites are the subcutaneous and deep neck soft tissues.


name: Stage IIIA Uterine Corpus Leiomyosarcoma AJCC v8

description: Stage IIIA includes: T3a, N0, M0. T3a: Uterine corpus leiomyosarcoma with tumor infiltrating abdominal tissues at one site. N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 8th Ed.)


name: Stage I Uterine Corpus Leiomyosarcoma AJCC v8

description: Stage I includes: T1, N0, M0. T1: Uterine corpus leiomyosarcoma with tumor limited to the uterus. N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 8th Ed.)


name: Stage IV Uterine Corpus Leiomyosarcoma AJCC v8

description: Stage IV includes: IVA: T4, Any N, M0; IVB: Any T, Any N, M1. T4: Uterine corpus leiomyosarcoma with tumor invading bladder or rectum. M0: No distant metastasis. M1: Distant metastasis (excluding adnexa, pelvic, and abdominal tissues). (from AJCC 8th Ed.)


Primary leiomyosarcoma

description: Leiomyosarcoma that is confined to a specific site without evidence of spread to other anatomic sites.


EBV-Related Leiomyosarcoma

description: Leiomyosarcoma that is caused by Epstein-Barr virus infection.


Inferior Vena Cava Leiomyosarcoma

description: An aggressive malignant smooth muscle neoplasm, arising from the inferior vena cava.  It is characterized by a proliferation of neoplastic spindle cells.


Metastatic leiomyosarcoma

description: A leiomyosarcoma that has spread to other anatomic sites.


leiomyosarcoma of appendix

description: A rare leiomyosarcoma that arises from the appendiceal wall.


Unresectable Soft Tissue Leiomyosarcoma

description: A soft tissue leiomyosarcoma that is not amenable to surgical resection.


name: Stage IVA Uterine Corpus Leiomyosarcoma AJCC v8

description: Stage IVA includes: T4, Any N, M0. T4: Uterine corpus leiomyosarcoma with tumor invading bladder or rectum. M0: No distant metastasis. (from AJCC 8th Ed.)


Conjunctival Leiomyosarcoma

description: A leiomyosarcoma that arises from the conjunctiva.


Seminal Vesicle Leiomyosarcoma

description: A rare leiomyosarcoma that affects the seminal vesicle.


name: Stage IB Uterine Corpus Leiomyosarcoma AJCC v8

description: Stage IB includes: T1b, N0, M0. T1b: Uterine corpus leiomyosarcoma with tumor limited to the uterus, measuring more than 5 cm in greatest dimension. N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 8th Ed.)


Pleomorphic leiomyosarcoma

description: A leiomyosarcoma characterized by the presence of poorly differentiated areas with pleomorphic appearance, in addition to areas with typical morphologic features.


Refractory Leiomyosarcoma

description: Leiomyosarcoma that does not respond to treatment.


Leiomyosarcoma of Vessels

description: An aggressive malignant smooth muscle neoplasm, arising from the walls of the vascular system.  It is characterized by a proliferation of neoplastic spindle cells.


leiomyosarcoma of bladder

description: A leiomyosarcoma that arises from the bladder. It is the most common type of bladder sarcoma in adults.


Broad Ligament Leiomyosarcoma

description: A rare leiomyosarcoma that arises from the broad ligament.


name: Unresectable Uterine Corpus Leiomyosarcoma

description: Uterine corpus leiomyosarcoma that is not amenable to surgical resection.


Advanced Soft Tissue Leiomyosarcoma

description: A soft tissue leiomyosarcoma that has spread extensively to other anatomic sites or is no longer responding to treatment.


name: Stage IIIB Uterine Corpus Leiomyosarcoma AJCC v8

description: Stage IIIB includes: T3b, N0, M0. T3b: Uterine corpus leiomyosarcoma with tumor infiltrating abdominal tissues at more than one site. N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 8th Ed.)


name: Uterine Corpus Leiomyosarcoma by AJCC v8 Stage

description: A term that refers to the staging of uterine corpus leiomyosarcoma according to the American Joint Committee on Cancer, 8th edition.


name: Stage IIIC Uterine Corpus Leiomyosarcoma AJCC v8

description: Stage IIIC includes: T1-3, N1, M0. T1: Uterine corpus leiomyosarcoma with tumor limited to the uterus. T2: Uterine corpus leiomyosarcoma with tumor extending beyond the uterus, within the pelvis. T3: Uterine corpus leiomyosarcoma with tumor infiltrating abdominal tissues. N1: Regional lymph node metastasis. M0: No distant metastasis. (AJCC 8th Ed.)


Childhood Leiomyosarcoma

description: An aggressive malignant smooth muscle neoplasm, occurring in children.  It is characterized by a proliferation of neoplastic spindle cells.


Leiomyosarcoma recurrent

description: The reemergence of leiomyosarcoma after a period of remission


name: Locally Recurrent Uterine Corpus Leiomyosarcoma

description: The reemergence of uterine corpus leiomyosarcoma after a period of remission, at or adjacent to the site of the original tumor.


name: Stage III Uterine Corpus Leiomyosarcoma AJCC v8

description: Stage III includes: IIIA: T3a, N0, M0; IIIB: T3b, N0, M0; IIIC: T1-3, N1, M0. T1: Uterine corpus leiomyosarcoma with tumor limited to the uterus. T2: Uterine corpus leiomyosarcoma with tumor extending beyond the uterus, within the pelvis. T3: Uterine corpus leiomyosarcoma with tumor infiltrating abdominal tissues. T3a: Uterine corpus leiomyosarcoma with tumor infiltrating abdominal tissues at one site. T3b: Uterine corpus leiomyosarcoma with tumor infiltrating abdominal tissues at more than one site. N0: No regional lymph node metastasis. N1: Regional lymph node metastasis. M0: No distant metastasis. (AJCC 8th Ed.)


Thyroid Gland Leiomyosarcoma

description: A leiomyosarcoma that arises from the thyroid gland.


name: Metastatic Uterine Corpus Leiomyosarcoma

description: Uterine corpus leiomyosarcoma that has spread from its original site of growth to another anatomic site.


name: Locally Advanced Uterine Corpus Leiomyosarcoma

description: Uterine corpus leiomyosarcoma that has spread to nearby tissues or lymph nodes.


Colorectal Leiomyosarcoma

description: An aggressive malignant smooth muscle neoplasm that arises from the colon or rectum.  It is characterized by a proliferation of neoplastic spindle cells.


Metastatic Soft Tissue Leiomyosarcoma

description: A soft tissue leiomyosarcoma that has spread from the original site of growth to another anatomic site.


Sinonasal Leiomyosarcoma

description: A leiomyosarcoma that arises from the nasal cavity and paranasal sinuses.


Well Differentiated Leiomyosarcoma

description: Grade I malignant smooth muscle neoplasm.  It is characterized by a proliferation of neoplastic spindle cells.


name: Stage IA Uterine Corpus Leiomyosarcoma AJCC v8

description: Stage IA includes: T1a, N0, M0. T1a: Uterine corpus leiomyosarcoma with tumor limited to the uterus, measuring 5 cm or less in greatest dimension. N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 8th Ed.)


Digestive System Leiomyosarcoma

description: A leiomyosarcoma arising from an anatomic site in the digestive system.


Resectable Leiomyosarcoma

description: Leiomyosarcoma that is amenable to surgical resection.


Advanced Leiomyosarcoma

description: A leiomyosarcoma that has spread extensively to other anatomic sites or is no longer responding to treatment.


name: Locally Advanced Soft Tissue Leiomyosarcoma

description: Soft tissue leiomyosarcoma that has spread to nearby tissues or lymph nodes.


Locally Advanced Leiomyosarcoma

description: A leiomyosarcoma that has spread from its original site of growth to nearby tissues or lymph nodes.


Leiomyosarcoma of Deep Soft Tissue

description: A rare leiomyosarcoma that arises from the deep soft tissue in the retroperitoneum or abdominal cavity.


name: Refractory Malignant Soft Tissue Neoplasm

description: Malignant soft tissue neoplasm that is resistant to treatment.


Refractory Extrarenal Rhabdoid Tumor

description: Extrarenal rhabdoid tumor that is  resistant to treatment.


Digestive System Solitary Fibrous Tumor

description: A solitary fibrous tumor arising from an anatomic site in the digestive system, including the esophagus, gallbladder, liver, pancreas, small bowel mesentery, and the serosal surfaces of the stomach and colon.


Skin tumor of smooth muscle origin

description: A smooth muscle neoplasm occurring in the skin.


Pilar Leiomyoma

description: A cutaneous leiomyoma arising from the arrector pili muscle.


An acyl-CoA that results from the formal condensation of the thiol group of coenzyme A with the carboxy group of oscr#9


Refractory Paraganglioma

description: A paraganglioma that does not respond to treatment.


name: Refractory Adrenal Gland Pheochromocytoma

description: A pheochromocytoma that does not respond to treatment.


Stage IB Uterine Corpus Cancer AJCC v8

description: Stage IB includes: T1b, N0, M0. T1b: Uterine corpus carcinoma or carcinosarcoma with tumor invading one half or more of the myometrium. N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 8th Ed.)


An unsymmetrical C3 cyanine dye having benzothiazolium-2-yl and quinolinium-4-yl substituents.


tetraacetic acid lactone

A member of the class of 2-pyranones that is 2H-pyran-2-one which is substituted at positions 4 and 6 by hydroxy and acetonyl groups, respectively.


A member of the class of benzofurans consisting of a 1-benzofuran skeleton and its substituted derivatives thereof.


A fatty acid ester that is egonol-9(Z),12(Z)linoleate in which the methoxy group at position 7 is replaced by a hydrogen. Isolated from the fruits of Styrax agrestis, it exhibits inhibitory activity against acetylcholinesterase.


EGONOL

A member of the class of 1-benzofurans that is 1-benzofuran substituted by a methoxy group at position 7, a 1,3-benzodioxol-5-yl group at position 2 and a 3-hydroxypropyl group at position 5. It has been isolated from Styrax agrestis.


(R)-furametpyr

A 5-chloro-1,3-dimethyl-N-(1,1,3-trimethyl-1,3-dihydro-2-benzofuran-4-yl)pyrazole-4-carboxamide that is the (R)-enantiomer of furametpyr.


rhuscholide A

A member of the class of 1-benzofurans that is 1-benzofuran-2(3H)-one substituted by a hydroxy group at position 5, a propan-2-ylidene group at position 3 and a (2E,6E,10E)-3,7,11,15-tetramethylhexadeca-2,6,10,14-tetraen-1-yl group at position 7. Isolated from Rhus chinensis, it exhibits anti-HIV activity.


glycosmisic acid

A guaiacyl lignin that is found in Arabidopsis thaliana.


EGONOLPROPANOATE

A fatty acid ester obtained by the formal condensation of egonol with propionic acid. It has been isolated from the fruits of Styrax agrestis.


EGONOLBUTANOATE

A butanoate ester of  egonol isolated from the fruits of Styrax agrestis.


(+)-dehydrodiconiferyl alcohol

A dehydrodiconiferyl alcohol that has (2S,3R)-configuration. A natural product isolated from several plant species including Allium sativum and Codonopsis pilosula.


ZOLASARTAN

A member of the class of 1-benzofurans that is 3-bromo-1-benzofuran which is substituted by a 2-(1H-tetrazol-5-yl)phenyl group at position 2 and by a (2-butyl-5-carboxy-4-chloro-1H-imidazol-1-yl)methyl group at position 5. It is an angiotensin II receptor type 1 (AT1) antagonist and was in clinical trials for the treatment of hypertension (now discontinued).


GLYCOSMISIC ACID

A member of the class of 1-benzofurans that is a lignan obtained by cyclodimerisation of ferulic acid.


furametpyr

A racemate comprising equimolar amounts of (R)- and (S)-furametpyr. A fungicide used to control rice sheath blight.


aurones

Any member of the class of 1-benzofurans with an arylmethylidene substituent at position 2. The term was originally restricted to natural products, but is now also used to describe semi-synthetic and fully synthetic compounds.


glycosmisic acid 4'-sulfate

A guaiacyl lignin that is glycosmisic acid in which the phenolic hydrogen is replaced by a sulfo group.


A fatty acid ester obtained by the formal condensation of egonol with linoleic acid. Isolated from the fruits of Styrax agrestis, it exhibits inhibitory activity against acetylcholinesterase.


A fatty acid ester obtained by the formal condensation of egonol with isobutyric acid. It has been isolated from the fruits of Styrax agrestis.


DEHYDROCONIFERYL ALCOHOL

A dehydrodiconiferyl alcohol that has (2R,3S)-configuration. It is a natural product isolated from several plant species including Aglaia foveolata, Viburnum erosum and Rosa multiflora.


egonol-2'''-methyl butanoate

A fatty acid ester obtained by the formal condensation of  (S)-2-methylbutyric acid with  egonol. It has been isolated from the fruits of Styrax agrestis.


(S)-furametpyr

A 5-chloro-1,3-dimethyl-N-(1,1,3-trimethyl-1,3-dihydro-2-benzofuran-4-yl)pyrazole-4-carboxamide that is the (S)-enantiomer of furametpyr.


(+)-geodin

An oxaspiro compound that is 3H,4'H-spiro[[1]benzofuran-2,1'-cyclohexa[2,5]diene]-3,4'-dione substituted by methoxycarbonyl, hydroxy, chloro, methyl, methoxy and chloro groups at positions 2', 4, 5, 6, 6' and 7, respectively. It is a fungal metabolite isolated from Aspergillus terreus and Penicillium glabrum.


7-demethoxyegonol oleate

A fatty acid ester that is egonol oleate in which the methoxy group at position 7 is replaced by a hydrogen. Isolated from the fruits of Styrax agrestis, it exhibits inhibitory activity against acetylcholinesterase.


burchellin

A neolignan with formula C20H20O5 that is isolated from Ocotea cymbarum and Piper wallichii. It is active against a variety of parasites including T. cruzi, the vector for Chagas disease.


EGONOL GLUCOSIDE

A beta-D-glucoside that is egonol in which the hydroxy hydrogen has been replaced by a beta-D-glucosyl residue.


SILICRISTIN A

A flavonolignan isolated from Silybum marianum and has been shown to exhibit inhibitory activities against lipoxygenase and prostaglandin synthetase.


EGONOL OLEATE

A fatty acid ester obtained by the formal condensation of egonol with oleic acid. It has been isolated from the fruits of Styrax agrestis.


A fatty acid ester that is egonol-2'''-methyl butanoate in which the methoxy group at position 7 is replaced by a hydrogen. It has been isolated from the fruits of Styrax agrestis and Styrax obassia.


DEMETHOXYEGONOL

A member of the class of 1-benzofurans that is  egonol in which the methoxy group at position 7 is replaced by a hydrogen. It has been isolated from the fruits of Styrax agrestis.


simulanol

A guaiacyl lignin that is found in Arabidopsis thaliana.


(2R,3S)-glycosmisic acid

A member of the class of 1-benzofurans that is a lignan obtained by cyclodimerisation of ferulic acid. It is isolated from several plants including spearmint.


fumimycin

A member of the class of 1-benzofurans that is 1-benzofuran-2(3H)-one substituted by a propenyl group at position 4, hydroxy groups at positions 5 and 6, methyl group at position 3 and a [(2E)-3-carboxyprop-2-enoyl]nitrilo group at position 3. Isolated from the fermentation broth of Aspergillus fumisynnematus F746, it exhibits antibacterial activity.


A member of the class of 1-benzofurans that is 2,3-dihydro-1-benzofuran substituted by a hydroxy group at position 3, a hydroxyisopropyl group at position 2, a carboxy group at position 5 and a prenyl group at position 7 (the 2S,3S stereoisomer) . Isolated from the rhizomes of Atractylodes lancea, it exhibits cytotoxicity against cancer cell lines HCT-116 and MKN-45.


aureusidin 6-O-beta-glucoside

A beta-D-glucoside in which a beta-D-glucopyranosyl residue is attached at position 6 of aureusidin via a glycosidic linkage.


hydroxybenzoic acid

Any benzoic acid carrying one or more phenolic hydroxy groups on the benzene ring.


A monohydroxybenzoic acid that is 2,5-dihydroxybenzoic acid in which the phenolic hydrogen at position 5 has been replaced by a beta-D-glucosyl residue.


5-CHLOROSALICYLIC ACID

A monohydroxybenzoic acid that is 2-hydroxybenzoic acid (salicylic acid) in which the hydrogen at position 5 is replaced by chlorine.


3,5-dichloro-4-hydroxybenzoic acid

A derivative of p-salicylic acid with chloro- substituents at C-3 and C-5 of the benzene ring.


3-amino-5-hydroxybenzoic acid

A monohydroxybenzoic acid that is 3-hydroxybenzoic acid carrying an additional amino substitutent at position 4.


A monohydroxybenzoic acid that is 2,5-dihydroxybenzoic acid in which the phenolic hydrogen at position 2 has been replaced by a beta-D-glucosyl residue.


A monohydroxybenzoic acid that is benzoic acid substituted by a hydroxy group at position 6 and a 2-phenylethenyl group at position 2 which in turn is attached to a beta-D-glucopyranosyloxy group at position 4. It has been isolated from the roots of Scorzonera judaica.


3-amino-4-hydroxybenzoic acid

A monohydroxybenzoic acid that is 4-hydroxybenzoic acid carrying an additional amino substitutent at position 3.


platensimycin A1

A  polycyclic cage that is the 5-hydroxy derivative of  platensimycin. It is isolated from Streptomyces platensis.


platencin A1

A polycyclic cage that is the 9-hydroxy derivative of platencin. It is isolated from Streptomyces platensis.


3-amino-2,4-dihydroxybenzoic acid

An aminobenzoic acid that is benzoic acid substituted by hydroxy groups at positions 2 and 4, and by an amino group at position 3.


PLATENCIN A3

A  polycyclic cage that is the 4-hydroxy derivative of  platencin. It is isolated from Streptomyces platensis.


platencin A2

A polycyclic cage that is the 3-hydroxy derivative of platencin. It is isolated from Streptomyces platensis.


methoxysalicylic acid

A monohydroxybenzoic acid that is salicylic acid which carries a methoxy group.


monohydroxybenzoic acid

Any hydroxybenzoic acid having a single phenolic hydroxy substituent on the benzene ring.


3-hydroxy-4-methylanthranilic acid

An aminobenzoic acid that is anthranilic acid substituted by a hydroxy group at position 3 and a methyl group at position 4.


dihydroxybenzoic acid

Any member of the class of  hydroxybenzoic acids carrying  two phenolic hydroxy groups on the benzene ring and its derivatives.


phosphatidylethanolamine 36:2

A phosphatidylethanolamine in which the acyl groups at C-1 and C-2 contain 36 carbons in total with 2 double bonds.


A phosphatidylethanolamine 36:2 in which both acyl groups have 18 carbons and 1 double bond each (position not specified).


(R)-lamenallenic acid

The (R)-enantiomer of lamenallenic acid.


lamenallenic acid

An allenic octadecatrienic acid having the allenic group at position 5 and a trans double bond at the 16-position.


(S)-lamenallenic acid

The (S)-enantiomer of lamenallenic acid.


Methyl ester of 8-(tetracyclo[6.4.0.0(2,7).0(3,6)]dodec-10-yl)octanoate, an octanoic acid, which is terminally substituted by [3]-ladderane, a structure consisting out of three fused butane rings and one fused hexane ring. Ladderane fatty acid methyl esters are core lipids of anammox bacteria.


name: Beta-Catenin-Activated Inflammatory Hepatocellular Adenoma

description: Hepatocellular adenoma with features of both beta-catenin-activated hepatocellular adenoma and inflammatory hepatocellular adenoma.


mahuannin D

A proanthocyanidin isolated form Ephedra sinica.


proanthocyanidin

A flavonoid oligomer obtained by the the condensation of two or more units of hydroxyflavans.


arecatannin a2

a class of condensed tannins in the sub-class procyanidins contained in the seeds of Areca catechu also called betel nut. The arecatannin-type natural products from Ceylonese cassia bark and Areca seed are examples polyphenols by both current definitions, and fit the distinct definition of a polymeric phenol as well.


procyanidin B8

A proanthocyanidin that is (+)-catechin and (-)-epicatechin units joined by a bond between positions 4 and 6' respectively in an alpha-configuration. Procyanidin B8 is found in acorn and is present in fruit and leaves of blackberry (Rubus fruticosus), raspberry (Rubus idaeus) and cowberry (Vaccinium vitis idaea). It can be also found in grape seeds and in beer.


A proanthocyanidin consisting of (-)-epigallocatechin and (-)-epicatechin units joined by a (4beta->8)-linkage.


PROANTHOCYANIDIN A2

A proanthocyanidin obtained by the condensation of (-)-epicatechin units.


A proanthocyanidin consisting of (+)-catechin and (+)-gallocatechin units joined by a (4alpha->6)-linkage.


A proanthocyanidin consisting of (+)-gallocatechin and (-)-epicatechin units joined by a (4alpha->8)-linkage.


cinnamtannin A2

A proanthocyanidin isolated from Cinnamomum cassia.


procyanidin B4

A proanthocyanidin obtained by the condensation of (-)-epicatechin and (+)-catechin units.


parameritannin A-1

A  proanthocyanidin  found in Cinnamomum cassia and Parameria laevigata.


A proanthocyanidin that is a doubly linked dimer composed of (-)-epicatechin and (-)-epigallocatechin as its flavanol units. Isolated from the wood of Xanthoceras sorbifolium, it exhibits inhibitory activity towards HIV-1 protease.


A proanthocyanidin consisting of (+)-gallocatechin and (+)-catechin units joined by a (4beta->8)-linkage.


A proanthocyanidin consisting of (+)-gallocatechin and (+)-catechin units joined by a (4alpha->6)-linkage.


A proanthocyanidin consisting of two molecules of (-)-epicatechin joined by a (4alpha->8)-linkage.


A proanthocyanidin consisting of (-)-epicatechin and (-)-epigallocatechin units joined by a (4beta->8)-linkage.


A proanthocyanidin consisting of (-)-epicatechin and (+)-gallocatechin units joined by a (4beta->8)-linkage.


A proanthocyanidin consisting of (+)-catechin and (-)-epigallocatechin units joined by a (4alpha->8)-linkage.


procyanidin

oligomeric compounds, formed from catechin and epicatechin molecules. They yield cyanidin when depolymerized under oxidative conditions.


A proanthocyanidin consisting of (-)-epigallocatechin and (+)-catechin units joined by a (4alpha->6)-linkage.


A biflavonoid consisting of two molecules of afzelechin joined by a (4alpha->8) linkage.


PROCYANIDIN C1

A proanthocyanidin consisting of three (-)-epicatechin units joined by two successive (4beta->8)-linkages.


procyanidin B5

A proanthocyanidin  consisting of two molecules of (-)-epicatechin joined by a bond between positions 4 and 6' in beta-configuration. It can be found in grape seeds, in Hibiscus cannabinus (kenaf) root and bark, in apple and in cacao.


PROCYANIDIN B2

A proanthocyanidin consisting of two molecules of (-)-epicatechin joined by a bond between positions 4 and 8' in a beta-configuration. Procyanidin B2 can be found in Cinchona pubescens (Chinchona, in the rind, bark and cortex), in Cinnamomum verum (Ceylon cinnamon, in the rind, bark and cortex), in Crataegus monogyna (Common hawthorn, in the flower and blossom), in Uncaria guianensis (Cat's claw, in the root), in Vitis vinifera (Common grape vine, in the leaf), in Litchi chinensis (litchi, in the pericarp), in the apple, in Ecdysanthera utilis and in red wine.


A  proanthocyanidin isolated from Cinnamomum cassia.


arecatannin B1

A proanthocyanidin consisting of two (-)-epicatechin and one (+)-catechin units joined in sequence by (4beta->8)- and (4beta->6)-linkages.


A proanthocyanidin consisting of (+)-gallocatechin and (+)-catechin units joined by a (4alpha->8)-linkage.


DRACORUBIN

A proanthocyanidin isolated from Dracaena draco.


PROCYANIDIN B1

A proanthocyanidin consisting of (-)-epicatechin and (+)-catechin units joined by a bond between positions 4 and 8' respectively  in a beta-configuration.. Procyanidin B1 can be found in Cinnamomum verum (Ceylon cinnamon, in the rind, bark or cortex), in Uncaria guianensis (cat's claw, in the root), and in Vitis vinifera (common grape vine, in the leaf) or in peach.


CASSIATANNIN A

A   proanthocyanidin isolated from the bark of Cinnamomum cassia.


procyanidin B3

A proanthocyanidin consisting of two molecules of (+)-catechin joined by a bond between positions 4 and 8' in alpha-configuration. It can be found in red wine, in barley, in beer, in peach or in Jatropha macrantha, the Huanarpo Macho.


cinnamtannin B1

A  proanthocyanidin found in Cinnamomum cassia and Cinnamomum zeylanicum.


procyanidin B6

A proanthocyanidin consisting of two molecules of (+)-catechin joined by a bond between positions 4 and 6' in alpha-configuration. Procyanidin B6 is isolated from leaves and fruit of cowberry Vaccinium vitis-idaea and other plants. It can also be found in grape seeds and in beer.


CINNAMTANNIN D1

A proanthocyanidin found in Cinnamomum cassia.


A secondary fatty alcohol that is hexadecane substituted by a hydroxy group at position 2.


aspirin-triggered protectin D1

A dihydroxydocosahexaenoic acid that is (4Z,7Z,11E,13E,15Z,19Z)-docosahexaenoic acid in which the two hydroxy substituents are located at positions 10 and 17 (the 10R,17R-stereoisomer).


A glycerophosphoethanolamine compound having an alk-1-enyl substituent at the 1-position and an acyl substituent at the 2-position.


phosphatidylethanolamine P-34:1

A 1-(alk-1-enyl)-2-acyl-sn-glycero-3-phosphoethanolamine in which the alkyl chain at position 1 and the acyl group at position 2 contain a total of 34 carbons and 1 additional double bond.


phosphatidylethanolamine P-36:1

A 1-(alk-1-enyl)-2-acyl-sn-glycero-3-phosphoethanolamine in which the alkyl chain at position 1 and the acyl group at position 2 contain a total of 36 carbons and 1 additional double bond.


phosphatidylethanolamine P-34:3

A 1-(alk-1-enyl)-2-acyl-sn-glycero-3-phosphoethanolamine in which the alkyl chain at position 1 and the acyl group at position 2 contain a total of 34 carbons and 3 additional double bonds.


A 1-(alk-1-enyl)-2-acyl-sn-glycero-3-phosphoethanolamine in which the alkyl and the acyl groups at positions 1 and 2 are specified as (1Z)-hexadecenyl and (8Z,11Z,14Z)-icosatrienoyl respectively.


A 1-(alk-1-enyl)-2-acyl-sn-glycero-3-phosphoethanolamine in which the alkyl and the acyl groups at positions 1 and 2 are specified as (1Z,9Z)-octadecadienyl and (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl respectively.


A 1-(alk-1-enyl)-2-acyl-sn-glycero-3-phosphoethanolamine in which the alkenyl and acyl groups are specified as (1Z)-hexadecenyl and arachidonoyl respectively.


phosphatidylethanolamine P-34:2

A 1-(alk-1-enyl)-2-acyl-sn-glycero-3-phosphoethanolamine in which the alkyl chain at position 1 and the acyl group at position 2 contain a total of 34 carbons and 2 additional double bonds.


A 1-(alk-1-enyl)-2-acyl-sn-glycero-3-phosphoethanolamine in which the alk-1-enyl and acyl groups are specified as (1Z,11Z)-octadecadienyl and oleoyl respectively.


A 1-(alk-1-enyl)-2-acyl-sn-glycero-3-phosphoethanolamine in which the alk-1-enyl and acyl groups are specified as (1Z)-octadecenyl and (9Z)-octadecenoyl respectively.


phosphatidylethanolamine P-38:2

A 1-(alk-1-enyl)-2-acyl-sn-glycero-3-phosphoethanolamine in which the alkyl chain at position 1 and the acyl group at position 2 contain a total of 38 carbons and 2 additional double bonds.


A phosphatidylethanolamine P-38:4 in which the 1-alkenyl group contains 16 carbons and no additional double bonds while the acyl group contains 22 carbons and 4 double bonds.


A 1-(alk-1-enyl)-2-acyl-sn-glycero-3-phosphoethanolamine in which the alk-1-enyl and acyl groups are specified as (1Z)-octadecenyl and (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl respectively.


phosphatidylethanolamine P-36:2

A 1-(alk-1-enyl)-2-acyl-sn-glycero-3-phosphoethanolamine in which the alkyl chain at position 1 and the acyl group at position 2 contain a total of 36 carbons and 2 additional double bonds.


A 1-(alk-1-enyl)-2-acyl-sn-glycero-3-phosphoethanolamine in which the alkyl and the acyl groups at positions 1 and 2 are specified as (1Z)-hexadecenyl and (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl respectively.


A 1-(alk-1-enyl)-2-acyl-sn-glycero-3-phosphoethanolamine in which the alk-1-enyl and acyl group are specified as (Z)-hexadec-1-enyl and hexadecanoyl (palmitoyl) respectively.


A 1-(alk-1-enyl)-2-acyl-sn-glycero-3-phosphoethanolamine in which the alkyl and the acyl groups at positions 1 and 2 are specified as (1Z)-octadecenyl and hexadecanoyl respectively.


phosphatidylethanolamine P-38:3

A 1-(alk-1-enyl)-2-acyl-sn-glycero-3-phosphoethanolamine in which the alkyl chain at position 1 and the acyl group at position 2 contain a total of 38 carbons and 3 additional double bonds.


A 1-(alk-1-enyl)-2-acyl-sn-glycero-3-phosphoethanolamine in which the alkyl and the acyl groups at positions 1 and 2 are specified as (1Z,11Z)-octadecadienyl and linoleoyl respectively.


A 1-(alk-1-enyl)-2-acyl-sn-glycero-3-phosphoethanolamine in which the alkenyl and acyl groups are specified as (1Z)-hexadecenyl and linoleoyl respectively.


phosphatidylethanolamine P-38:1

A 1-(alk-1-enyl)-2-acyl-sn-glycero-3-phosphoethanolamine in which the alkyl chain at position 1 and the acyl group at position 2 contain a total of 38 carbons and 1 additional double bond.


phosphatidylethanolamine P-40:7

A 1-(alk-1-enyl)-2-acyl-sn-glycero-3-phosphoethanolamine in which the alkyl chain at position 1 and the acyl group at position 2 contain a total of 40 carbons and 7 additional double bonds.


A 1-(alk-1-enyl)-2-acyl-sn-glycero-3-phosphoethanolamine in which the alkyl and the acyl groups at positions 1 and 2 are specified as (1Z)-octadecenyl and (4Z,7Z,10Z,13Z,16Z)-docosapentaenoyl respectively.


phosphatidylethanolamine P-20:0

A 1-(alk-1-enyl)-2-acyl-sn-glycero-3-phosphoethanolamine in which the alkyl chain at position 1 and the acyl group at position 2 contain a total of 20 carbons and no additional double bonds.


phosphatidylethanolamine P-36:5

A 1-(alk-1-enyl)-2-acyl-sn-glycero-3-phosphoethanolamine in which the alkyl chain at position 1 and the acyl group at position 2 contain a total of 36 carbons and 5 additional double bonds.


A 1-(alk-1-enyl)-2-acyl-sn-glycero-3-phosphoethanolamine in which the alk-1-enyl and acyl groups are specified as octadecadienyl and icosatetraenoyl respectively.


A 1-(alk-1-enyl)-2-acyl-sn-glycero-3-phosphoethanolamine in which the alkenyl and acyl groups are specified asas (1Z)-octadecenyl and linoleoyl respectively.


phosphatidylethanolamine P-40:4

A 1-(alk-1-enyl)-2-acyl-sn-glycero-3-phosphoethanolamine in which the alkyl chain at position 1 and the acyl group at position 2 contain a total of 40 carbons and 4 additional double bonds.


A 1-(alk-1-enyl)-2-acyl-sn-glycero-3-phosphoethanolamine in which the alk-1-enyl and acyl groups are specified as (1Z,11Z)-octadecadienyl and palmitoyl respectively.


phosphatidylethanolamine P-38:4

A 1-(alk-1-enyl)-2-acyl-sn-glycero-3-phosphoethanolamine in which the alkyl chain at position 1 and the acyl group at position 2 contain a total of 38 carbons and 4 additional double bonds.


A 1-(alk-1-enyl)-2-acyl-sn-glycero-3-phosphoethanolamine in which the alk-1-enyl and acyl groups are specified as (1Z)-octadecenyl and arachidonoyl respectively.


A 1-(alk-1-enyl)-2-acyl-sn-glycero-3-phosphoethanolamine in which the alkyl and the acyl groups at positions 1 and 2 are specified as (1Z)-octadecenyl and (8Z,11Z,14Z)-icosatrienoyl respectively.


1-(alk-1-enyl)-2-acyl-sn-glycero-3-phosphoethanolamine in which the alkyl and the acyl groups at positions 1 and 2 are specified as (1Z)-hexadecenyl and oleoyl respectively.


A 1-(alk-1-enyl)-2-acyl-sn-glycero-3-phosphoethanolamine that is the 1-O-(hexadec-1-enyl)-2-O-octadeca-9,12-dienoyl derivative of sn-glycero-3-phosphoethanolamine.


Acute esophagitis

description: An acute inflammatory process affecting the esophageal wall.


(R)-bromazine hydrochloride

The hydrochloride salt of (R)-bromazine.


Refractory Rhabdoid Tumor of the Kidney

description: A rhabdoid tumor of the kidney that does not respond to treatment.


Recurrent Rhabdoid Tumor of the Kidney

description: The reemergence of a rhabdoid tumor of the kidney after a period of remission.


name: Unresectable Rhabdoid Tumor of the Kidney

description: Rhabdoid tumor of the kidney that is not amenable to surgical resection.


Gastrointestinal stromal tumor, benign

description: A gastrointestinal stromal tumor that is characterized by a maximum diameter equal or less than 5 cm (gastric localization), or equal or less than 2 cm (intestinal localization) and no more than 5 mitotic figures per 50 high power fields.


name: Benign Gastric Gastrointestinal Stromal Tumor

description: A gastrointestinal stromal tumor arising from the stomach.  It is characterized by a maximum diameter equal or less than 5 cm and no more than 5 mitotic figures per 50 high power fields.


name: Stage IA Hepatocellular Carcinoma AJCC v8

description: Stage IA includes: T1a, N0, M0. T1a: Solitary tumor equal to or less than 2 cm.  N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 8th ed.)


name: Stage I Hepatocellular Carcinoma AJCC v8

description: Stage I includes: IA (T1a, N0, M0); IB (T1b, N0, M0). T1a: Solitary tumor equal to or less than 2 cm.  T1b: Solitary tumor larger than 2 cm without vascular invasion. N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 8th ed.)


name: Stage IB Hepatocellular Carcinoma AJCC v8

description: Stage IB includes: T1b, N0, M0. T1b: Solitary tumor larger than 2 cm without vascular invasion. N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 8th ed.)


name: potassium aluminium sulfate dodecahydrate

description: A hydrate resulting from the the formal combination of anhydrous potassium aluminium sulfate with 12 mol eq. of water.


POTASSIUM METAPHOSPHATE

A potassium salt of metaphosphoric acid.


POTASH, SULFURATED

A potassium salt that is the dipotassium salt of carbonic acid.


potassium phosphate

An inorganic potassium salt that is the tripotassium salt of phosphoric acid.


inorganic potassium salt

A potassium salt that lacks C-H bonds


POTASSIUM FLUORIDE

A fluoride salt having K+ as the counterion.


potassium salt

Any alkali metal salt having potassium(1+) as the cation.


Breast Myoid Hamartoma

description: A breast hamartoma characterized by the predominance of a smooth muscle component.


An acyclic mixed acid anhydride that results from the formal condensation of the phosphoryl group of AMP with the carboxy group of 17-(4-hydroxyphenyl)heptadecanoic acid.


A butan-4-olide having a 3-bromopropyl group at the 3-position and two methyl substituents at the 5-position.


callophycol A

A dibromophenol that is 2,4-dibromophenol substituted at position 6 by a decahydronaphthalen-1-ylmethyl group which in turn is substituted by a bromo, 3-bromo-4-chloro-4-methylpentyl group, two methyl groups and a methylidene group at positions 6, 5, 5, 8a and 2 respectively. A diterpenoid isolated from the Fijian red alga Callophycus serratus, it exhibits antibacterial, antimalarial and anticancer activities.


FENPROPIMORPH

A racemate comprising equimolar amounts of (R)- and (S)-fenpropimorph. It is a systemic fungicide, used to control a variety of fungal diseases in cereal crops.


WITHALONGOLIDE B

A withanolide that is 27-deoxywithaferin A substituted by a hydroxy group at position 19. Isolated from Physalis longifolia, it exhibits antineoplastic activity.


name: Colorectal Microvesicular Hyperplastic Polyp

description: A serrated hyperplastic polyp that arises from the colon and rectum.  It is characterized by the presence of microvacuolated columnar cells that are admixed with small numbers of goblet cells.  There is no evidence of epithelial atypia or dysplasia.


Refractory Visual Pathway Glioma

description: Visual pathway glioma that is resistant to treatment.


(-)-minovincinine

A monoterpenoid indole alkaloid that is (-)-vincadifformine which carries a hydroxy group at position 19R. A natural product found in several plant species including Catharanthus roseus and Vinca minor.


A carbobicyclic compound that is bicyclo[3.2.1]oct-3-en-2-one which is substituted at positions 3 and 4 by 2-chloro-4-(methylsulfonyl)benzoyl and phenylthio groups, respectively.


name: Stage II Gastric Neuroendocrine Tumor AJCC v8

description: Stage II includes: (T2, N0, M0); (T3, N0, M0). T2: Tumor invading the muscularis propria or is greater than 1 cm in size. T3: Tumor invading through the muscularis propria into subserosal tissue without penetration of overlying serosa. N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 8th ed.)


The cationic form of a C3 cyanine dye having 3,3-dimethyl-1-octadecylindoleinine units at each end.


C5-indocyanine cation

The cationic form of a C5 cyanine dye having 1-ethyl-3,3-dimethylindoleinine units at each end.


A C5 cyanine dye having 1-ethyl-3,3-dimethylindoleinine units at each end.


The cationic form of a C5 cyanine dye having 3,3-dimethyl-1-octadecylindoleinine units at each end.


Cy5-bifunctional dye

An iminium betaine derived from a Cy5 dye.


(+)-EPITAXIFOLIN

A taxifolin that has (2S,3R)-configuration.


name: Dysembryoplastic Neuroepithelial-Like Tumor of the Septum Pellucidum

description: A very rare, low-grade midline brain neoplasm that affects the septum pellucidum. It is characterized by similar histological features to those found in dysembryoplastic neuroepithelial tumor, but does not display multinodularity. It usually manifests with symptoms related to increased intracranial pressure. Epilepsy has been reported in approximately one third of patients. PDGFRA gene mutations have been identified in the majority of patients. Alterations in FGFR1 and NF1 genes have also been reported. BRAF mutations which represent the most common molecular alteration found in cortical dysembryoplastic neuroepithelial tumor, were absent in this rare group of midline tumors.