AXIN1_HUMAN Axin-1 (sprot)

An Axin-1 that is encoded in the genome of human.


name: PLCE_HUMAN 1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon (sprot)

description: A 1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon that is encoded in the genome of human.


name: GPR3_HUMAN G-protein coupled receptor 3 (sprot)

description: A G-protein coupled receptor 3 that is encoded in the genome of human.


name: NFIP1_HUMAN NEDD4 family-interacting protein 1 (sprot)

description: A NEDD4 family-interacting protein 1 that is encoded in the genome of human.


cloxacillin

A semisynthetic penicillin antibiotic carrying a 3-(2-chlorophenyl)-5-methylisoxazole-4-carboxamido group at position 6.


CCNF_HUMAN Cyclin-F (sprot)

A cyclin-F that is encoded in the genome of human.


name: AFF4_HUMAN AF4/FMR2 family member 4 (sprot)

description: An AF4/FMR2 family member 4 that is encoded in the genome of human.


hypopigmentation of the skin

category: biolink:Disease biolink:DiseaseOrPhenotypicFeature biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing

description: A condition caused by a deficiency or a loss of melanin pigmentation in the epidermis, also known as hypomelanosis. Hypopigmentation can be localized or generalized, and may result from genetic defects, trauma, inflammation, or infections.


phosphatidylethanolamine (18:2/18:2)

A phosphatidylethanolamine 36:4 in which both acyl groups contain 18 carbons and 2 double bonds.


Waldenstrom macroglobulinemia

description: Waldenstrom macroglobulinemia in a patient who has at least one first degree relative with either Waldenstrom macroglobulinemia or another B-cell lymphoproliferative disorder.


name: KI2L4_HUMAN Killer cell immunoglobulin-like receptor 2DL4 (sprot)

description: A killer cell immunoglobulin-like receptor 2DL4 that is encoded in the genome of human.


apixaban

A pyrazolopyridine that is 7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide substituted at position 1 by a 4-methoxyphenyl group and at position 6 by a 4-(2-oxopiperidin-1-yl)phenyl group. It is used for the prevention and treatment of thromboembolic diseases.


name: IKZF1_HUMAN DNA-binding protein Ikaros (sprot)

description: A DNA-binding protein Ikaros that is encoded in the genome of human.


autoimmune thrombocytopenia

description: An autoimmune form of thrombocytopenia.


name: LPIN3_HUMAN Phosphatidate phosphatase LPIN3 (sprot)

description: A phosphatidate phosphatase LPIN3 that is encoded in the genome of human.


nimodipine

A dihydropyridine that is 1,4-dihydropyridine which is substituted by methyl groups at positions 2 and 6, a (2-methoxyethoxy)carbonyl group at position 3, a m-nitrophenyl group at position 4, and an isopropoxycarbonyl group at position 5. An L-type calcium channel blocker, it acts particularly on cerebral circulation, and is used both orally and intravenously for the prevention and treatment of subarachnoid hemorrhage from ruptured intracranial aneurysm.


peripartum cardiomyopathy

description: Peripartum cardiomyopathy (PPCM) is an idiopathic, potentially fatal form of dilated cardiomyopathy that develops during the final month of pregnancy or within five months after delivery.


name: DSN1_HUMAN Kinetochore-associated protein DSN1 homolog (sprot)

description: A kinetochore-associated protein DSN1 that is encoded in the genome of human.


canine mammary carcinoma

description: Mammary carcinoma occurring in a dog.


name: SPS1_HUMAN Selenide, water dikinase 1 (sprot)

description: A selenide, water dikinase 1 that is encoded in the genome of human.


GLYCERYL TRIOLEATE

A triglyceride formed by esterification of the three hydroxy groups of glycerol with oleic acid. Triolein is one of the two components of Lorenzo's oil.


diabetic encephalopathy

description: A brain disease that is characterized by functional impairment of cognition, cerebral signal conduction, neurotransmission and synaptic plasticity, and underlying structural pathology associated with diabetes.


name: PSMD7_HUMAN 26S proteasome non-ATPase regulatory subunit 7 (sprot)

description: A 26S proteasome non-ATPase regulatory subunit 7 that is encoded in the genome of human.


PENTANAL

A saturated fatty aldehyde composed from five carbons in a straight chain.


MATN2_HUMAN Matrilin-2 (sprot)

A matrilin-2 that is encoded in the genome of human.


name: MFAP1_HUMAN Microfibrillar-associated protein 1 (sprot)

description: A microfibrillar-associated protein 1 that is encoded in the genome of human.


temporal arteritis

description: A large vessel vasculitis predominantly involving the arteries originating from the aortic arch and especially the extracranial branches of the carotid arteries.


AZOXYSTROBIN

An aryloxypyrimidine having a 4,6-diphenoxypyrimidine  skeleton in which one of the phenyl rings is cyano-substituted at C-2 and the other carries a 2-methoxy-1-(methoxycarbonyl)vinyl substituent, also at C-2. An inhibitor of mitochondrial respiration by blocking electron transfer between cytochromes b and c1, it is used widely as a fungicide in agriculture.


infigratinib

A member of the class of phenylureas that is urea in which a hydrogen attached to one of the nitrogens is replaced by a 2,6-dichloro-3,5-dimethoxyphenyl group, while the hydrogens attached to the other nitrogen are replaced by a methyl group and a 6-{[4-(4-ethylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl group. It is a potent and selective fibroblast growth factor receptor inhibitor.


name: RT11_HUMAN Small ribosomal subunit protein uS11m (sprot)

description: A small ribosomal subunit protein uS11m that is encoded in the genome of human.


Hemobilia

category: biolink:PhenotypicFeature biolink:DiseaseOrPhenotypicFeature biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing

description: Bleeding into the biliary tree.


5-methoxysalicylic acid

A methoxysalicylic acid that is salicylic acid which is carrying a methoxy group at position 5.


PHB1_HUMAN Prohibitin 1 (sprot)

A prohibitin 1 that is encoded in the genome of human.


ketotifen

An organic heterotricyclic compound that is 4,9-dihydro-10H-benzo[4,5]cyclohepta[1,2-b]thiophen-10-one which is substituted at position 4 by a 1-methylpiperidin-4-ylidene group. A blocker of histamine H1 receptors with a stabilising action on mast cells, it is used (usually as its hydrogen fumarate salt) for the treatment of asthma, where it may take several weeks to exert its full effect.


testicular cancer

description: A primary or metastatic malignant neoplasm that affects the testis. Representative examples include seminoma, embryonal carcinoma, sarcoma, leukemia, and lymphoma.


name: NECA1_HUMAN N-terminal EF-hand calcium-binding protein 1 (sprot)

description: An N-terminal EF-hand calcium-binding protein 1 that is encoded in the genome of human.


A carboxamide, the structure of which is that of acetamide substituted on carbon by a 2',3-dimethyl-2,4'-bipyridin-5-yl group and on nitrogen by a 5-(pyrazin-2-yl)pyridin-2-yl group. It is a highly potent, selective and orally bioavailable Porcupine inhibitor (a Wnt signalling inhibitor).


parasitemia

description: The presence of parasites (especially malarial parasites) in the blood. (Dorland, 27th ed)


PATUPILONE

An epithilone that is epithilone D in which the double bond in the macrocyclic ring has been oxidised to the corresponding epoxide (the S,S stereoisomer).


name: NPTX1_HUMAN Neuronal pentraxin-1 (sprot)

description: A neuronal pentraxin-1 that is encoded in the genome of human.


XPO1_HUMAN Exportin-1 (sprot)

An exportin-1 that is encoded in the genome of human.


name: KCJ10_HUMAN ATP-sensitive inward rectifier potassium channel 10 (sprot)

description: An ATP-sensitive inward rectifier potassium channel 10 that is encoded in the genome of human.


inherited neurodegenerative disorder

description: An inherited disorder characterized by progressive degeneration and atrophy of the nervous system.


name: SMC2_HUMAN Structural maintenance of chromosomes protein 2 (sprot)

description: A structural maintenance of chromosomes protein 2 that is encoded in the genome of human.


name: LRCC1_HUMAN Leucine-rich repeat and coiled-coil domain-containing protein 1 (sprot)

description: A leucine-rich repeat and coiled-coil domain-containing protein 1 that is encoded in the genome of human.


name: AT2B1_HUMAN Plasma membrane calcium-transporting ATPase 1 (sprot)

description: A plasma membrane calcium-transporting ATPase 1 that is encoded in the genome of human.


Fanconi-like syndrome

description: A syndrome characterized by pancytopenia, immune deficiency and cutaneous malignancies.


telangiectasis

description: Local dilatation of small vessels resulting in red discoloration of the skin or mucous membranes.


name: AGR2_HUMAN Anterior gradient protein 2 homolog (sprot)

description: An anterior gradient protein 2 that is encoded in the genome of human.


phosphatidylcholine (18:1/22:5)

A phosphatidylcholine 40:6 in which the fatty acyl groups at positions 1 and 2 are specified as C18:1 and C22:5 respectively.


name: ELK4_HUMAN ETS domain-containing protein Elk-4 (sprot)

description: An ETS domain-containing protein Elk-4 that is encoded in the genome of human.


name: SRGP1_HUMAN SLIT-ROBO Rho GTPase-activating protein 1 (sprot)

description: A SLIT-ROBO Rho GTPase-activating protein 1 that is encoded in the genome of human.


name: SRGP2_HUMAN SLIT-ROBO Rho GTPase-activating protein 2 (sprot)

description: A SLIT-ROBO Rho GTPase-activating protein 2 that is encoded in the genome of human.


name: GLSK_HUMAN Glutaminase kidney isoform, mitochondrial (sprot)

description: A glutaminase kidney isoform, mitochondrial that is encoded in the genome of human.


name: DEPD7_HUMAN DEP domain-containing protein 7 (sprot)

description: A DEP domain-containing protein 7 that is encoded in the genome of human.


name: RHEB_HUMAN GTP-binding protein Rheb (sprot)

description: A GTP-binding protein Rheb that is encoded in the genome of human.


name: PWP3A_HUMAN PWWP domain-containing DNA repair factor 3A (sprot)

description: A PWWP domain-containing DNA repair factor 3A that is encoded in the genome of human.


KLK6_HUMAN Kallikrein-6 (sprot)

A kallikrein-6 that is encoded in the genome of human.


A substituted aniline that is benzamide in which one of the meta- hydrogens is replaced by an amino group.


name: EHD2_HUMAN EH domain-containing protein 2 (sprot)

description: An EH domain-containing protein 2 that is encoded in the genome of human.


REBECCAMYCIN

An N-glycosyl compound consisting of a heteropolycyclic ring system with a glucosyl group attached to one of the indolic nitrogens.


name: TNNT3_HUMAN Troponin T, fast skeletal muscle (sprot)

description: A troponin T, fast skeletal muscle that is encoded in the genome of human.


name: EPN4_HUMAN Clathrin interactor 1 (sprot)

description: A clathrin interactor 1 that is encoded in the genome of human.


CNTN1_HUMAN Contactin-1 (sprot)

A contactin-1 that is encoded in the genome of human.


name: EIF2A_HUMAN Eukaryotic translation initiation factor 2A (sprot)

description: A eukaryotic translation initiation factor 2A that is encoded in the genome of human.


name: myalgic encephalomeyelitis/chronic fatigue syndrome

description: A medical condition characterized by long-term fatigue and other symptoms that limit a person's ability to carry out ordinary daily activities.


AGO4_HUMAN Protein argonaute-4 (sprot)

A protein argonaute-4 that is encoded in the genome of human.


name: CTIP_HUMAN DNA endonuclease RBBP8 (sprot)

description: A DNA endonuclease RBBP8 that is encoded in the genome of human.


name: KGP1_HUMAN cGMP-dependent protein kinase 1 (sprot)

description: A cGMP-dependent protein kinase 1 that is encoded in the genome of human.


Wolfram syndrome

description: Wolfram syndrome (WS) also known as DIDMOAD, is a neurodegenerative disorder characterized by type I diabetes mellitus (DM), diabetes insipidus (DI), sensorineural deafness (D), bilateral optical atrophy (OA) and neurological signs. Other related problems are urinary tract atony, ataxia, peripheral neuropathy, psychiatric disorders and/or seizures. 2 types of WS may be distinguished: type 1 and type 2 (WS1 and WS2).


name: GRK6_HUMAN G protein-coupled receptor kinase 6 (sprot)

description: A G protein-coupled receptor kinase 6 that is encoded in the genome of human.


MYH14_HUMAN Myosin-14 (sprot)

A myosin-14 that is encoded in the genome of human.


CASPA_HUMAN Caspase-10 (sprot)

A caspase-10 that is encoded in the genome of human.


name: CNOT1_HUMAN CCR4-NOT transcription complex subunit 1 (sprot)

description: A CCR4-NOT transcription complex subunit 1 that is encoded in the genome of human.


name: AL1A3_HUMAN Retinaldehyde dehydrogenase 3 (sprot)

description: A retinaldehyde dehydrogenase 3 that is encoded in the genome of human.


embryonal carcinoma

description: A non-seminomatous malignant germ cell tumor characterized by the presence of large germ cells with abundant cytoplasm resembling epithelial cells, geographic necrosis, high mitotic activity, and pseudoglandular and pseudopapillary structures formation. It can arise from the testis, ovary, and extragonadal sites (central nervous system and mediastinum).


HXK1_HUMAN Hexokinase-1 (sprot)

A hexokinase-1 that is encoded in the genome of human.


name: OSMR_HUMAN Oncostatin-M-specific receptor subunit beta (sprot)

description: An oncostatin-M-specific receptor subunit beta that is encoded in the genome of human.


CERS6_HUMAN Ceramide synthase 6 (sprot)

A ceramide synthase 6 that is encoded in the genome of human.


atovaquone

A naphthoquinone compound having a 4-(4-chlorophenyl)cyclohexyl group at the 2-position and a hydroxy substituent at the 3-position.


name: ANM2_HUMAN Protein arginine N-methyltransferase 2 (sprot)

description: A protein arginine N-methyltransferase 2 that is encoded in the genome of human.


name: C2C2L_HUMAN Phospholipid transfer protein C2CD2L (sprot)

description: A phospholipid transfer protein C2CD2L that is encoded in the genome of human.


MALTOTRIOSE

A maltotriose trisaccharide in which the glucose residue at the reducing end is in the pyranose ring form and has alpha configuration at the anomeric carbon atom..


name: SUZ12_HUMAN Polycomb protein SUZ12 (sprot)

description: A polycomb protein SUZ12 that is encoded in the genome of human.


name: RS14_HUMAN Small ribosomal subunit protein uS11 (sprot)

description: A eukaryotic-type small ribosomal subunit protein uS11 that is encoded in the genome of human.


name: DPS1_HUMAN All trans-polyprenyl-diphosphate synthase PDSS1 (sprot)

description: An all trans-polyprenyl-diphosphate synthase PDSS1 that is encoded in the genome of human.


name: PRD13_HUMAN PR domain zinc finger protein 13 (sprot)

description: A PR domain zinc finger protein 13 that is encoded in the genome of human.


name: KCNN3_HUMAN Small conductance calcium-activated potassium channel protein 3 (sprot)

description: A small conductance calcium-activated potassium channel protein 3 that is encoded in the genome of human.


name: DIDO1_HUMAN Death-inducer obliterator 1 (sprot)

description: A death-inducer obliterator 1 that is encoded in the genome of human.


LOBELINE

An optically active piperidine alkaloid having a 2-oxo-2-phenylethyl substituent at the 2-position and a 2-hydroxy-2-phenylethyl group at the 6-position.


name: RAB12_HUMAN Ras-related protein Rab-12 (sprot)

description: A Ras-related protein Rab-12 that is encoded in the genome of human.


name: AT11B_HUMAN Phospholipid-transporting ATPase IF (sprot)

description: A phospholipid-transporting ATPase IF that is encoded in the genome of human.


name: UFO_HUMAN Tyrosine-protein kinase receptor UFO (sprot)

description: A tyrosine-protein kinase receptor UFO that is encoded in the genome of human.


gonorrhea

description: A common sexually transmitted bacterial infection caused by Neisseria gonorrhoeae. It is transmitted through vaginal, oral, or anal intercourse. Infected individuals may be asymptomatic. Symptoms in males include burning sensation during urination, discharge from the penis, and painful swelling of the testes. Symptoms in females include painful urination, vaginal discharge, and vaginal bleeding between periods. If untreated, the infection may lead to pelvic inflammatory disease.


ANFY1_HUMAN Rabankyrin-5 (sprot)

A rabankyrin-5 that is encoded in the genome of human.


NRX1B_HUMAN Neurexin-1-beta (sprot)

A neurexin-1-beta that is encoded in the genome of human.


peptic ulcer disease

description: A digestive system disease characterized by discontinuation in the inner lining of the gastrointestinal (GI) tract because of gastric acid secretion or pepsin.


Insulin-resistant diabetes mellitus

description: A type of diabetes mellitus related not to lack of insulin but rather to lack of response to insulin on the part of the target tissues of insulin such as muscle, fat, and liver cells. This type of diabetes is typically associated with increases both in blood glucose concentrations as well as in fasting and postprandial serum insulin levels.


name: BPIA1_HUMAN BPI fold-containing family A member 1 (sprot)

description: A BPI fold-containing family A member 1 that is encoded in the genome of human.


obstructive nephropathy

description: Renal damage and impaired renal function secondary to urinary tract obstruction.


cartilage-hair hypoplasia

description: Cartilage-hair hypoplasia is a disease affecting the bone metaphyses causing small stature from birth.


name: NDEL1_HUMAN Nuclear distribution protein nudE-like 1 (sprot)

description: A nuclear distribution protein nudE-like 1 that is encoded in the genome of human.


name: TNIP1_HUMAN TNFAIP3-interacting protein 1 (sprot)

description: A TNFAIP3-interacting protein 1 that is encoded in the genome of human.


name: KCP_HUMAN Kielin/chordin-like protein (sprot)

description: A cysteine-rich motor neuron 2 protein that is encoded in the genome of human.


JAK inhibitor I

An organic heterotetracyclic compound that is 1,6-dihydrobenzo[h]imidazo[4,5-f]isoquinolin-7-one bearing additional tert-butyl and fluoro substituents at positions 2 and 9 respectively.


Neurogenic bladder

description: A type of bladder dysfunction caused by neurologic damage. Neurogenic bladder can be flaccid or spastic. Common manifestatios of neurogenic bladder are overflow incontinence, frequency, urgency, urge incontinence, and retention.


TLR6_HUMAN Toll-like receptor 6 (sprot)

A Toll-like receptor 6 that is encoded in the genome of human.


TOLUENE DIISOCYANATE

A toluene meta-diisocyanate in which the isocyanato groups are at positions 2 and 4 relative to the methyl group on the benzene ring.


name: PTN20_HUMAN Tyrosine-protein phosphatase non-receptor type 20 (sprot)

description: A tyrosine-protein phosphatase non-receptor type 20 that is encoded in the genome of human.


corneal disorder

description: A non-neoplastic or neoplastic disorder that affects the cornea. Representative examples include keratitis, bullous keratopathy, and squamous cell carcinoma.


Turner syndrome

description: Turner syndrome is a chromosomal disorder associated with the complete or partial absence of an X chromosome.


kidney neoplasm

description: A benign or malignant neoplasm affecting the kidney. Representative examples of benign renal neoplasms include fibroma, lipoma, oncocytoma, and juxtaglomerular cell tumor. Representative examples of malignant renal neoplasms include renal cell carcinoma, renal pelvis carcinoma, Wilms tumor, rhabdoid tumor, sarcoma, and lymphoma.


anxiety disorder

description: A category of psychiatric disorders which are characterized by anxious feelings or fear often accompanied by physical symptoms associated with anxiety.


name: ZN395_HUMAN Zinc finger protein 395 (sprot)

description: A zinc finger protein 395 that is encoded in the genome of human.


metamizole

A pyrazole that is antiipyrine substituted at C-4 by a methyl(sulfomethyl)amino group, the sodium salt of which, metamizole sodium, was widely used as a powerful analgesic and antipyretic, but withdrawn from many markets from the 1970s due to a risk of causing risk of causing agranulocytosis.


CATA_HUMAN Catalase (sprot)

A catalase that is encoded in the genome of human.


name: P20L1_HUMAN PHD finger protein 20-like protein 1 (sprot)

description: A PHD finger protein 20-like protein 1 that is encoded in the genome of human.


CD5L_HUMAN CD5 antigen-like (sprot)

A CD5 molecule-like that is encoded in the genome of human.


Beckwith-Wiedemann syndrome

description: Beckwith-Wiedemann syndrome (BWS) is a genetic disorder characterized by overgrowth, tumor predisposition and congenital malformations.


name: I12R2_HUMAN Interleukin-12 receptor subunit beta-2 (sprot)

description: An interleukin-12 receptor subunit beta-2 that is encoded in the genome of human.


name: ATG4C_HUMAN Cysteine protease ATG4C (sprot)

description: A cysteine protease ATG4C that is encoded in the genome of human.


osteonecrosis

description: A none disease characterized by death of bone tissue due to a lack of blood supply.


phosphatidylcholine (18:0/20:3)

A phosphatidylcholine 38:3 in which the fatty acyl groups at positions 1 and 2 are specified as C18:0 and C20:3 respectively.


name: DNAI1_HUMAN Dynein axonemal intermediate chain 1 (sprot)

description: A dynein axonemal intermediate chain 1 that is encoded in the genome of human.


name: HPCA_HUMAN Neuron-specific calcium-binding protein hippocalcin (sprot)

description: A neuron-specific calcium-binding protein hippocalcin that is encoded in the genome of human.


Hodgkin's lymphoma, mixed cellularity

description: A subtype of classical Hodgkin lymphoma with scattered Reed-Sternberg and Hodgkin cells in a diffuse or vaguely nodular mixed inflammatory background without nodular sclerosing fibrosis. (WHO, 2008)


3,4,5-trimethoxycinnamic acid

A methoxycinnamic acid with three methoxy substituents at the 3-, 4- and 5-positions.


iron dextran

Please consider adding concept for iron dextran. CAS# 9004-66-4. Thank you.


ANTIMYCIN A

A nine-membered bis-lactone having methyl substituents at the 2- and 6-positions, an n-hexyl substituent at the 8-position, an acyloxy substituent at the 7-position and an aroylamido substituent at the 3-position. It is produced by Streptomyces bacteria and has found commercial use as a fish poison.


name: TM50A_HUMAN Transmembrane protein 50A (sprot)

description: A transmembrane protein 50A that is encoded in the genome of human.


phosphatidylethanolamine (18:0/18:2)

1,2-diacyl-sn-glycero-3-phosphoethanolamine in which the acyl group at C-1 contains 18 carbons and no double bonds while that at C-2 contains 18 carbons and 2 double bonds.


premature menopause

description: Cessation of menstruation before the age of 40. Symptoms include hot flashes, night sweats, mood swings, and decreased sex drive.


name: congenital adrenal hyperplasia due to 11-beta-hydroxylase deficiency

description: Congenital adrenal hyperplasia due to 11 beta-hydroxylase (CYP11B1) deficiency is a rare form of congenital adrenal hyperplasia (CAH) characterized by glucocorticoid deficiency, hyperandrogenism, hypertension and virilization in females.


name: ERD22_HUMAN ER lumen protein-retaining receptor 2 (sprot)

description: An ER lumen protein-retaining receptor 2 that is encoded in the genome of human.


ABI1_HUMAN Abl interactor 1 (sprot)

An Abl interactor 1 that is encoded in the genome of human.


name: CSK_HUMAN Tyrosine-protein kinase CSK (sprot)

description: A tyrosine-protein kinase CSK that is encoded in the genome of human.


2-hydroxyisobutyric acid

A 2-hydroxy monocarboxylic acid that is isobutyric acid bearing a hydroxy substituent at position 2. It is a metabolite of  methyl tertiary-butyl ether.


name: TRAF1_HUMAN TNF receptor-associated factor 1 (sprot)

description: A TNF receptor-associated factor 1 that is encoded in the genome of human.


name: TCPA_HUMAN T-complex protein 1 subunit alpha (sprot)

description: A T-complex protein 1 subunit alpha that is encoded in the genome of human.


name: primary cutaneous anaplastic large cell lymphoma

description: Primary cutaneous anaplastic large cell lymphoma (C-ALCL) is a rare T-cell non-Hodgkin lymphoma that affects the skin and generally shows no extracutaneous involvement at presentation. It belongs to the spectrum of primary cutaneous CD30+ lymphoproliferative disorders along with lymphomatoid papulosis with which it shares overlapping clinical and histopathologic features.


guaiacol

A  monomethoxybenzene that consists of phenol with a methoxy substituent at the ortho position.


name: GALT6_HUMAN Polypeptide N-acetylgalactosaminyltransferase 6 (sprot)

description: A polypeptide N-acetylgalactosaminyltransferase 6 that is encoded in the genome of human.


Hutchinson-Gilford progeria syndrome

description: Hutchinson-Gilford progeria syndrome is a rare, fatal, autosomal dominant and premature aging disease, beginning in childhood and characterized by growth reduction, failure to thrive, a typical facial appearance (prominent forehead, protuberant eyes, thin nose with a beaked tip, thin lips, micrognathia and protruding ears) and distinct dermatologic features (generalized alopecia, aged-looking skin, sclerotic and dimpled skin over the abdomen and extremities, prominent cutaneous vasculature, dyspigmentation, nail hypoplasia and loss of subcutaneous fat).


AFAM_HUMAN Afamin (sprot)

An afamin that is encoded in the genome of human.


name: S22AA_HUMAN Solute carrier family 22 member 10 (sprot)

description: A solute carrier family 22 member 10 that is encoded in the genome of human.


loxoprofen sodium hydrate

A hydrate that is the dihydrate form of loxoprofen sodium. The parent acid, loxoprofen, is a prodrug that is rapidly converted into its active trans-alcohol metabolite following oral administration.


name: UBP21_HUMAN Ubiquitin carboxyl-terminal hydrolase 21 (sprot)

description: A ubiquitin carboxyl-terminal hydrolase 21 that is encoded in the genome of human.


Appendiceal mucinous neoplasm

description: An epithelial neoplasm originating in the appendix and often associated with cystic dilation of the appendix due to accumulation of gelatinous material, morphologically referred to as mucoceles.


prochlorperazine

A member of the class of phenothiazines that is 10H-phenothiazine having a chloro substituent at the 2-position and a 3-(4-methylpiperazin-1-yl)propyl group at the N-10 position.


name: DLEC1_HUMAN Deleted in lung and esophageal cancer protein 1 (sprot)

description: A deleted in lung and esophageal cancer protein 1 that is encoded in the genome of human.


name: PRDM2_HUMAN PR domain zinc finger protein 2 (sprot)

description: A PR domain zinc finger protein 2 that is encoded in the genome of human.


name: SRP14_HUMAN Signal recognition particle 14 kDa protein (sprot)

description: A signal recognition particle 14 kDa protein that is encoded in the genome of human.


name: SRP09_HUMAN Signal recognition particle 9 kDa protein (sprot)

description: A signal recognition particle 9 kDa protein that is encoded in the genome of human.


name: LY86_HUMAN Lymphocyte antigen 86 (sprot)

description: A lymphocyte antigen 86 that is encoded in the genome of human.


name: ACHA4_HUMAN Neuronal acetylcholine receptor subunit alpha-4 (sprot)

description: A neuronal acetylcholine receptor subunit alpha-4 that is encoded in the genome of human.


name: ASB10_HUMAN Ankyrin repeat and SOCS box protein 10 (sprot)

description: An ankyrin repeat and SOCS box protein 10 that is encoded in the genome of human.


name: PTGR1_HUMAN Prostaglandin reductase 1 (sprot)

description: A prostaglandin reductase 1 that is encoded in the genome of human.


retinoschisis

description: An inherited or acquired disorder characterized by splitting of the retina into two layers. It results in loss of vision.


imipenem

A broad-spectrum, intravenous beta-lactam antibiotic of the carbapenem subgroup.


GLAUCARUBINONE

A quassinoid with formula C25H34O10. It is a natural product isolated from several plant species and exhibits anti-cancer and anti-malarial properties.


An adenosine bisphosphate having monophosphate groups at the 3'- and 5'-positions and a sulfo group attached to the phosphate at position 5'.


hemosiderosis

description: Accumulation of iron in internal organs.


rocuronium

A 5alpha-androstane compound having 3alpha-hydroxy-, 17beta-acetoxy-, 2beta-morpholino- and 16beta-N-allyllyrrolidinium substituents.


name: S38A4_HUMAN Sodium-coupled neutral amino acid transporter 4 (sprot)

description: A sodium-coupled neutral amino acid transporter 4 that is encoded in the genome of human.


3-HYDROXYBUTYRIC ACID, (+/-)-

A straight-chain 3-hydroxy monocarboxylic acid comprising a butyric acid core with a single hydroxy substituent in the 3- position; a ketone body whose levels are raised during ketosis, used as an energy source by the brain during fasting in humans. Also used to synthesise biodegradable plastics.


name: MRGX4_HUMAN Mas-related G-protein coupled receptor member X4 (sprot)

description: A Mas-related G-protein coupled receptor X4 that is encoded in the genome of human.


dezocine

(7S,8S)-7-Amino-8-methyl-5,6,7,8-tetrahydronaphthalen-2-ol in which the hydrogen at position 8 and one of the hydrogens at position 6 are substituted by each end of a tetramethylene bridge. A synthetic opioid analgesic, it has mixed opiod agonist and antagonist properties. Although it is used for pain management, it can produce opioid withdrawal syndrome in patients already dependent on other opioids, and its clinical application is limited by side effects such as dizziness.


recurrent pneumonia

description: Infections with nontuberculous mycobacteria (atypical mycobacteria): M. kansasii, M. marinum, M. scrofulaceum, M. flavescens, M. gordonae, M. obuense, M. gilvum, M. duvali, M. szulgai, M. intracellulare (see mycobacterium avium complex;), M. xenopi (littorale), M. ulcerans, M. buruli, M. terrae, M. fortuitum (minetti, giae), M. chelonae.


name: HBA_HUMAN Hemoglobin subunit alpha (sprot)

description: A hemoglobin subunit alpha that is encoded in the genome of human.


Rotavirus infection

description: Infection with any of the rotaviruses. Specific infections include human infantile diarrhea, neonatal calf diarrhea, and epidemic diarrhea of infant mice.


name: VPS28_HUMAN Vacuolar protein sorting-associated protein 28 homolog (sprot)

description: A vacuolar protein sorting-associated protein 28 that is encoded in the genome of human.


name: ECI2_HUMAN Enoyl-CoA delta isomerase 2 (sprot)

description: An enoyl-CoA Delta isomerase 2 that is encoded in the genome of human.


name: DDX27_HUMAN Probable ATP-dependent RNA helicase DDX27 (sprot)

description: A probable ATP-dependent RNA helicase DDX27 that is encoded in the genome of human.


name: HHATL_HUMAN Protein-cysteine N-palmitoyltransferase HHAT-like protein (sprot)

description: A protein-cysteine N-palmitoyltransferase HHAT-like protein that is encoded in the genome of human.


name: KCNJ4_HUMAN Inward rectifier potassium channel 4 (sprot)

description: An inward rectifier potassium channel 4 that is encoded in the genome of human.


name: CADM4_HUMAN Cell adhesion molecule 4 (sprot)

description: A cell adhesion molecule 4 that is encoded in the genome of human.


name: IRF2_HUMAN Interferon regulatory factor 2 (sprot)

description: An interferon regulatory factor 2 that is encoded in the genome of human.


name: BIRC1_HUMAN Baculoviral IAP repeat-containing protein 1 (sprot)

description: A baculoviral IAP repeat-containing protein 1 that is encoded in the genome of human.


name: NALP7_HUMAN NACHT, LRR and PYD domains-containing protein 7 (sprot)

description: A NACHT, LRR and PYD domains-containing protein 7 that is encoded in the genome of human.


name: USE1_HUMAN Vesicle transport protein USE1 (sprot)

description: A vesicle transport protein USE1 that is encoded in the genome of human.


name: DMAP1_HUMAN DNA methyltransferase 1-associated protein 1 (sprot)

description: A DNA methyltransferase 1-associated protein 1 that is encoded in the genome of human.


name: SC23B_HUMAN Protein transport protein Sec23B (sprot)

description: A protein transport protein Sec23B that is encoded in the genome of human.


name: TMED2_HUMAN Transmembrane emp24 domain-containing protein 2 (sprot)

description: A transmembrane emp24 domain-containing protein 2 that is encoded in the genome of human.


tetrabenazine

A 9,10-dimethoxy-3-isobutyl-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-one in which both stereocentres have S configuration.


hereditary angioedema

description: Hereditary angioedema (HAE) is a genetic disease characterized by the occurrence of transitory and recurrent subcutaneous and/or submucosal edemas resulting in swelling and/or abdominal pain.


name: UD16_HUMAN UDP-glucuronosyltransferase 1-6 (sprot)

description: A UDP-glucuronosyltransferase 1-6 that is encoded in the genome of human.


dihydroxyacetone phosphate

A member of the class of glycerone phosphates that consists of glycerone bearing a single phospho substituent.


aclarubicin

An anthracycline antibiotic that is produced by Streptomyces galilaeus and also has potent antineoplastic activity.


name: GFI1B_HUMAN Zinc finger protein Gfi-1b (sprot)

description: A zinc finger protein Gfi-1b that is encoded in the genome of human.


RUFY3_HUMAN Protein RUFY3 (sprot)

A protein RUFY3 that is encoded in the genome of human.


serotonin syndrome

description: Serotoninergic syndrome is characterized by an excess of serotonin in the central nervous system, associated with the use of various agents, including selective serotonin reuptake inhibitors (SSRIs).


name: ADAM8_HUMAN Disintegrin and metalloproteinase domain-containing protein 8 (sprot)

description: A disintegrin and metalloproteinase domain-containing protein 8 that is encoded in the genome of human.


name: CAR10_HUMAN Caspase recruitment domain-containing protein 10 (sprot)

description: A caspase recruitment domain-containing protein 10 that is encoded in the genome of human.


name: NKRF_HUMAN NF-kappa-B-repressing factor (sprot)

description: An NF-kappa-B-repressing factor that is encoded in the genome of human.


name: ZBT38_HUMAN Zinc finger and BTB domain-containing protein 38 (sprot)

description: A zinc finger and BTB domain-containing protein 38 that is encoded in the genome of human.


name: NALP4_HUMAN NACHT, LRR and PYD domains-containing protein 4 (sprot)

description: A NACHT, LRR and PYD domains-containing protein 4 that is encoded in the genome of human.


name: PSG3_HUMAN Pregnancy-specific beta-1-glycoprotein 3 (sprot)

description: A pregnancy-specific beta-1-glycoprotein 3 that is encoded in the genome of human.


cavernous hemangioma

description: A hemangioma characterized by the presence of cavernous vascular spaces.


name: RNF43_HUMAN E3 ubiquitin-protein ligase RNF43 (sprot)

description: An E3 ubiquitin-protein ligase RNF43 that is encoded in the genome of human.


name: THAP1_HUMAN THAP domain-containing protein 1 (sprot)

description: A THAP domain-containing protein 1 that is encoded in the genome of human.


savolitinib

A member of the class of triazolopyrazines that is 1H-[1,2,3]triazolo[4,5-b]pyrazine substituted by (1S)-1-(imidazo[1,2-a]pyridin-6-yl)ethyl and 1-methyl-1H-pyrazol-4-yl groups at positions 1 and 6, respectively. It is a highly selective MET tyrosine kinase inhibitor that is approved in China for advanced NSCLC with MET exon 14 skipping mutations.


name: PO3F2_HUMAN POU domain, class 3, transcription factor 2 (sprot)

description: A POU domain, class 3, transcription factor 2 that is encoded in the genome of human.


adrenal gland disorder

description: A disease involving the adrenal gland.


mammary analog secretory carcinoma

description: A salivary gland carcinoma that has material basis in a chromosomal translocation that results in an ETV6-NTRK3 fusion gene.


lipid-rich carcinoma

description: A carcinoma characterized by the presence of malignant epithelial cells with clear cytoplasm which contains neutral lipids. A representative example is the lipid-rich breast carcinoma.


Plasmodium falciparum malaria

description: Malaria resulting from infection by Plasmodium falciparum.


Wernicke-Korsakoff syndrome

description: Wernicke-Korsakoff syndrome is a brain disorder, due to thiamine deficiency that has been associated with both Wernicke's encephalopathy and Korsakoff syndrome. The term refers to two different syndromes, each representing a different stage of the disease. Wernicke's encephalopathy represents the 'acute' phase and Korsakoff's syndrome represents the 'chronic' phase. However, they are used interchangeable in many sites. Wernicke's encephalopathy is characterized by confusion, abnormal stance and gait (ataxia), and abnormal eye movements (nystagmus). Korsakoff's syndrome is observed in a small number of patients. It is a type of dementia, characterized by memory loss and confabulation (filling in of memory gaps with data the patient can readily recall) and involvement of the heart, vascular, and nervous system. Wernicke-Korsakoff syndrome mainly results from chronic alcohol use, but also from dietary deficiencies, prolonged vomiting, eating disorders, systemic diseases (cancer, AIDS, infections), bariatric surgery, transplants, or the effects of chemotherapy. Studies indicate that there may be some genetic predisposition for the disease.Treatment involves supplementing the diet with thiamine. Wernicke encephalopathy is an acute syndrome and requires emergency treatment to prevent death and neurologic complications. In cases where the diagnosis is not confirmed, patients should still be treated while additional evaluations are completed.


name: CKAP5_HUMAN Cytoskeleton-associated protein 5 (sprot)

description: A cytoskeleton-associated protein 5 that is encoded in the genome of human.


estramustine

A carbamate ester obtained by the formal condensation of the hydroxy group of 17beta-estradiol with the carboxy group of bis(2-chloroethyl)carbamic acid.


hand-foot syndrome

description: A condition characterized by redness, pain, swelling, and tingling in the palms of the hands or the soles of the feet. It may appear as a side effect to chemotherapy agents.


IL21_HUMAN Interleukin-21 (sprot)

An interleukin-21 that is encoded in the genome of human.


harmaline

A harmala alkaloid in which the harman skeleton is methoxy-substituted at C-7 and has been reduced across the 3,4 bond.


name: LPAR2_HUMAN Lysophosphatidic acid receptor 2 (sprot)

description: A lysophosphatidic acid receptor 2 that is encoded in the genome of human.


name: HIF1N_HUMAN Hypoxia-inducible factor 1-alpha inhibitor (sprot)

description: A hypoxia-inducible factor 1-alpha inhibitor that is encoded in the genome of human.


Intestinal edema

description: Accumulation of cell free, noninflammatony fluid within the wall of the intestinal tract producing uniform thickening of the mucosal folds.


tioconazole

A member of the class of imidazoles that comprises 2-(2,4-dichlorophenyl)ethylimidazole carrying an additional (2-chloro-3-thienyl)methoxy substituent at position 2.


PERF_HUMAN Perforin-1 (sprot)

A perforin-1 that is encoded in the genome of human.


cyanocobalamin

A complex cob(III)alamin in which cobalt is positioned in the centre of a planar corrin tetrapyrrole ring and bound axially to a 5,6-dimethylbenzimidazole moiety and a cyano group. It is one of several forms of the vitamin known as vitamin B12.


phosphatidylglycerol (18:2/16:1)

A phosphatidylglycerol 34:3 in which the acyl group at position 1 contains 18 carbons and two double bonds while that at position 2 contains 16 carbons and 1 double bond.


OLA1_HUMAN Obg-like ATPase 1 (sprot)

An obg-like ATPase 1 that is encoded in the genome of human.


name: OCRL_HUMAN Inositol polyphosphate 5-phosphatase OCRL (sprot)

description: An inositol polyphosphate 5-phosphatase OCRL that is encoded in the genome of human.


phosphatidylethanolamine (P-18:0/22:5)

A phosphatidylethanolamine P-40:5 in which the 1-alkenyl group contains 18 carbons and no additional double bonds while the acyl group contains 22 carbons and 5 double bonds.


yohimbine

An indole alkaloid with alpha2-adrenoceptor antagonist activity. It is produced by Corynanthe johimbe and Rauwolfia serpentina.


adenosarcoma

description: A low grade malignant neoplasm characterized by the presence of a benign epithelial component (tubular and cleft-like glands) and a low grade sarcomatous component that contains varying amounts of fibrous and smooth muscle tissues. In a minority of cases, the sarcomatous component contains heterologous elements including striated muscle, cartilage, and fat. It occurs in the uterine corpus, ovary, fallopian tube, cervix, and vagina. It may recur and in a minority of cases may metastasize to distant anatomic sites.


buspirone

An azaspiro compound that is 8-azaspiro[4.5]decane-7,9-dione substituted at the nitrogen atom by a 4-(piperazin-1-yl)butyl group which in turn is substituted by a pyrimidin-2-yl group at the N(4) position.


name: GCYB1_HUMAN Guanylate cyclase soluble subunit beta-1 (sprot)

description: A guanylate cyclase soluble subunit beta-1 that is encoded in the genome of human.


name: YPEL3_HUMAN Protein yippee-like 3 (sprot)

description: A protein yippee-like 3 that is encoded in the genome of human.


name: PRP31_HUMAN U4/U6 small nuclear ribonucleoprotein Prp31 (sprot)

description: A U4/U6 small nuclear ribonucleoprotein Prp31 that is encoded in the genome of human.


SNX7_HUMAN Sorting nexin-7 (sprot)

A sorting nexin-7 that is encoded in the genome of human.


name: DLG1_HUMAN Disks large homolog 1 (sprot)

description: A disks large homolog 1 that is encoded in the genome of human.


name: MAGI3_HUMAN Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3 (sprot)

description: A membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3 that is encoded in the genome of human.


esketamine

The S- (more active) enantiomer of ketamine.


silicosis

description: Silicosis is a respiratory disease caused by breathing in (inhaling) silica dust. There are three types of silicosis: Simple chronic silicosis, the most common type of silicosis, results from long-term exposure (usually more than 20years) to low amounts of silica dust. Simple chronic silicosismay causepeople to have difficulty breathing. Accelerated silicosis occurs after 5 to 15 yearsof exposure of higher levels of silica.Swelling of the lungsand other symptoms occur faster in this type of silicosis than in the simple chronic form. Acute silicosis results from short-term exposure (weeks or months) of large amounts of silica.The lungs become very inflamed and can fill with fluid, causing severe shortness of breath and low blood oxygen levels. A cough, weight loss, and fatigue may also be present. Acute silicosis progresses rapidly and can be fatal within months. People who work in jobs where they are exposed to silica dust (mining, quarrying, construction, sand blasting, stone cutting) are at risk of developing this condition.


lung large cell carcinoma

description: A poorly differentiated non-small cell lung carcinoma composed of large polygonal cells without evidence of glandular or squamous differentiation. There is a male predilection.


CD99_HUMAN CD99 antigen (sprot)

A CD99 molecule that is encoded in the genome of human.


name: FGFP1_HUMAN Fibroblast growth factor-binding protein 1 (sprot)

description: A fibroblast growth factor-binding protein 1 that is encoded in the genome of human.


phosphatidylethanolamine (16:0/18:1)

A phosphatidylethanolamine 34:1 in which the acyl group at C-1 contains 16 carbons and no double bonds while that at C-2 contains 18 carbons and 1 double bond.


masitinib

A member of the class of benzamides that is the carboxamide resulting from the formal condensation of the carboxy group of 4-[(4-methylpiperazin-1-yl)methyl]benzoic acid with the primary amino group of 4-methyl-N(3)-[4-(pyridin-3-yl)-1,3-thiazol-2-yl]benzene-1,3-diamine. It is a highly selective oral tyrosine kinase inhibitor.


name: CP8B1_HUMAN 7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase (sprot)

description: A cytochrome P450 8B1 that is encoded in the genome of human.


Choreoathetosis

description: Involuntary movements characterized by both athetosis (inability to sustain muscles in a fixed position) and chorea (widespread jerky arrhythmic movements).


phosphatidylcholine (17:0/18:1)

A phosphatidylcholine 35:1 in which the fatty acyl groups at positions 1 and 2 are specified as C17:0 and C18:1 respectively.


STX3_HUMAN Syntaxin-3 (sprot)

A syntaxin-3 that is encoded in the genome of human.


oxedrine

A  phenethylamine alkaloid that is 4-(2-aminoethyl)phenol substituted by a hydroxy group at position 1 and a methyl group at the amino nitrogen.


neoplasm of testis

description: A neoplasm (disease) that involves the testis.


insulin autoimmune syndrome

description: Insulin autoimmune syndrome is a rare condition that causes low blood sugar (hypoglycemia). This occurs because the body begins to make a specific kind of protein called antibodies to attack insulin. Insulin is a naturally occurring hormone that is responsible for keeping blood sugar at a normal level. When blood sugar levels get too high, insulin helps to store the sugar for future use. People affected by insulin autoimmune syndrome have antibodies that attack insulin, causing it to work too hard and the level of blood sugar to become too low. Insulin autoimmune syndrome most often begins during adulthood.


catatonia

description: A psychiatric disorder featuring stupor, posturing, and echophenomena.


name: IBP6_HUMAN Insulin-like growth factor-binding protein 6 (sprot)

description: An insulin-like growth factor-binding protein 6 that is encoded in the genome of human.


lincomycin

A carbohydrate-containing antibiotic produced by the actinomyces Streptomyces lincolnensis.


liver angiosarcoma

description: A malignant vascular neoplasm arising from the liver.


varlitinib

A member of the class of quinazolines that is quinazoline substituted by {3-chloro-4-[(1,3-thiazol-2-yl)methoxy]phenyl}amino and [(4R)-4-methyl-4,5-dihydro-1,3-oxazol-2-yl]amino groups at positions 4 and 6, respectively. It is a tyrosine kinase inhibitor of both ErbB-2 (Her-2/neu) and EGFR and has shown significant anti-tumour activity in preclinical models of human breast, lung, and epidermal carcinoma tumours.


doxercalciferol

A hydroxy seco-steroid and synthetic vitamin D2 analogue that undergoes metabolic activation in vivo to form 1alpha,25-dihydroxyvitamin D2 (1alpha,25-(OH)2D2), a naturally occurring, biologically active form of vitamin D2. It is used to treat secondary hyperparathyroidism, a condition in which the body produces excess parathyroid hormone (PTH; a natural substance needed to control the amount of calcium in the blood) in certain people with chronic kidney disease.


sulfhemoglobinemia

description: A morbid condition due to the presence of sulfmethemoglobin in the blood. It is marked by persistent cyanosis, but the blood count does not reveal any special abnormality in the blood. It is thought to be caused by the action of hydrogen sulfide absorbed from the intestine. (Stedman, 25th ed)


name: RIMS1_HUMAN Regulating synaptic membrane exocytosis protein 1 (sprot)

description: A regulating synaptic membrane exocytosis protein 1 that is encoded in the genome of human.


name: ARHG8_HUMAN Neuroepithelial cell-transforming gene 1 protein (sprot)

description: A neuroepithelial cell-transforming gene 1 protein that is encoded in the genome of human.


name: SUH_HUMAN Recombining binding protein suppressor of hairless (sprot)

description: A recombining binding protein suppressor of hairless that is encoded in the genome of human.


cranial nerve neuropathy

description: A neoplastic or non-neoplastic disorder that affects one of the cranial nerves.


carmustine

A member of the class of N-nitrosoureas that is 1,3-bis(2-chloroethyl)urea in which one of the nitrogens is substituted by a nitroso group.


Listeria meningitis

description: Inflammation of the meninges caused by listeria monocytogenes infection, usually occurring in individuals under the age of 3 years or over the age of 50 years. It may occur at any age in individuals with immunologic deficiency syndromes. Clinical manifestations include fever, altered mentation, headache, meningeal signs, focal neurologic signs, and seizures. (From Medicine 1998 Sep;77(5):313-36)


name: GFPT2_HUMAN Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 2 (sprot)

description: A glutamine--fructose-6-phosphate aminotransferase [isomerizing] 2 that is encoded in the genome of human.


name: ROR2_HUMAN Tyrosine-protein kinase transmembrane receptor ROR2 (sprot)

description: A tyrosine-protein kinase transmembrane receptor ROR2 that is encoded in the genome of human.


name: RL38_HUMAN Large ribosomal subunit protein eL38 (sprot)

description: A large ribosomal subunit protein eL38 that is encoded in the genome of human.


TAUROCHOLIC ACID

A bile acid taurine conjugate of  cholic acid that usually occurs as the sodium salt of bile in mammals.


name: ABCA8_HUMAN ABC-type organic anion transporter ABCA8 (sprot)

description: An ABC-type organic anion transporter ABCA8 that is encoded in the genome of human.


nonsyndromic congenital nail disorder 9

description: Deformity or discoloration of a fingernail or toenail.


name: TBC3I_HUMAN TBC1 domain family member 3I (sprot)

description: A protein that is a translation product of the TBC1D3I gene in human.


amiloride hydrochloride

A hydrochloride obtained by combining amiloride with one molar equivalent of hydrochloric acid.


name: DOCK8_HUMAN Dedicator of cytokinesis protein 8 (sprot)

description: A dedicator of cytokinesis protein 8 that is encoded in the genome of human.


congenital adrenal hyperplasia

description: Congenital adrenal hyperplasia (CAH) is an inherited endocrine disorder caused by a steroidogenic enzyme deficiency that is characterized by adrenal insufficiency and variable degrees of hyper or hypo androgyny manifestations, depending of the type and the severity of the disease.


DCD_HUMAN Dermcidin (sprot)

A dermcidin that is encoded in the genome of human.


name: F264_HUMAN 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 (sprot)

description: A 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 that is encoded in the genome of human.


The conjugate base of 4-hydroxybenzoic acid, comprising a 4-hydroxybenzoic acid core with a proton missing to give a charge of -1.


name: REQU_HUMAN Zinc finger protein ubi-d4 (sprot)

description: A zinc finger protein ubi-d4 that is encoded in the genome of human.


APOD_HUMAN Apolipoprotein D (sprot)

An apolipoprotein D that is encoded in the genome of human.


name: LHPL4_HUMAN LHFPL tetraspan subfamily member 4 protein (sprot)

description: An LHFPL tetraspan subfamily member 4 protein that is encoded in the genome of human.


name: LHPL3_HUMAN LHFPL tetraspan subfamily member 3 protein (sprot)

description: An LHFPL tetraspan subfamily member 3 protein that is encoded in the genome of human.


name: ETV3_HUMAN ETS translocation variant 3 (sprot)

description: An ETS translocation variant 3 that is encoded in the genome of human.


name: COX42_HUMAN Cytochrome c oxidase subunit 4 isoform 2, mitochondrial (sprot)

description: A cytochrome c oxidase subunit 4 isoform 2, mitochondrial that is encoded in the genome of human.


glucose metabolism disease

description: A metabolic disorder characterized by abnormal blood glucose levels.


carotid artery occlusion

description: A occlusion precerebral artery that involves the carotid artery segment.


tinea unguium

description: A fungal infection of the nail, usually caused by dermatophytes; yeasts; or nondermatophyte molds.


name: AAA1_HUMAN Asc-type amino acid transporter 1 (sprot)

description: An asc-type amino acid transporter 1 that is encoded in the genome of human.


venous thromboembolism

description: Occlusion of the lumen of a vein by a thrombus that has migrated from a distal site via the blood stream.


phosphatidylcholine (17:1/18:2)

A phosphatidylcholine 35:3 in which the fatty acyl groups at positions 1 and 2 are specified as C17:1 and C18:2 respectively.


name: CITE2_HUMAN Cbp/p300-interacting transactivator 2 (sprot)

description: A Cbp/p300-interacting transactivator 2 that is encoded in the genome of human.


lifitegrast

An N-acyl-L-alpha-amino acid obtained by formal condensation of the carboxy group of N-[2-(1-benzofuran-6-carbonyl)]-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxylic acid with the amino group of 3-(methanesulfonyl)-L-phenylalanine. Used for treatment of keratoconjunctivitis sicca (dry eye syndrome).


Functional intestinal obstruction

description: The blockage of bowel contents from evacuation; the causes are attributable to non-structural impediments, such as chemical imbalances or the side effects of medications, narcotics in particular.


PSN2_HUMAN Presenilin-2 (sprot)

A presenilin-2 that is encoded in the genome of human.


SYT4_HUMAN Synaptotagmin-4 (sprot)

A synaptotagmin-4 that is encoded in the genome of human.


name: NCF1_HUMAN Neutrophil cytosol factor 1 (sprot)

description: A neutrophil cytosol factor 1 that is encoded in the genome of human.


fosfomycin

A phosphonic acid having an (R,S)-1,2-epoxypropyl group attached to phosphorus.


name: UBAC1_HUMAN Ubiquitin-associated domain-containing protein 1 (sprot)

description: A ubiquitin-associated domain-containing protein 1 that is encoded in the genome of human.


BET1L_HUMAN BET1-like protein (sprot)

A BET1-like protein that is encoded in the genome of human.


pancreatic neuroendocrine neoplasm

description: A neoplasm with neuroendocrine differentiation that arises from the pancreas. It includes neuroendocrine tumors (low and intermediate grade) and neuroendocrine carcinomas (high grade).


phosphatidylcholine (20:4/22:6)

A phosphatidylcholine 42:10 in which the fatty acyl groups at positions 1 and 2 are specified as C20:4 and C22:6 respectively.


name: GANAB_HUMAN Neutral alpha-glucosidase AB (sprot)

description: A neutral alpha-glucosidase AB that is encoded in the genome of human.


name: LARP4_HUMAN La-related protein 4 (sprot)

description: A La-related protein 4 that is encoded in the genome of human.


name: ILRL2_HUMAN Interleukin-1 receptor-like 2 (sprot)

description: An interleukin-1 receptor-like 2 that is encoded in the genome of human.


name: KCNG3_HUMAN Potassium voltage-gated channel subfamily G member 3 (sprot)

description: A voltage-gated potassium channel subfamily G member 3 that is encoded in the genome of human.


An  ecdysteroid that is ecdysone substituted by a hydroxy group at position 20.


name: VGFR3_HUMAN Vascular endothelial growth factor receptor 3 (sprot)

description: A vascular endothelial growth factor receptor 3 that is encoded in the genome of human.


CD226_HUMAN CD226 antigen (sprot)

A CD226 molecule that is encoded in the genome of human.


name: DDX11_HUMAN ATP-dependent DNA helicase DDX11 (sprot)

description: An ATP-dependent DNA helicase DDX11 that is encoded in the genome of human.


CNTN6_HUMAN Contactin-6 (sprot)

A contactin-6 that is encoded in the genome of human.


name: RB11B_HUMAN Ras-related protein Rab-11B (sprot)

description: A Ras-related protein Rab-11B that is encoded in the genome of human.


name: FMO3_HUMAN Flavin-containing monooxygenase 3 (sprot)

description: A flavin-containing monooxygenase 3 that is encoded in the genome of human.


name: CAN2_HUMAN Calpain-2 catalytic subunit (sprot)

description: A calpain-2 catalytic subunit that is encoded in the genome of human.


name: CAC1D_HUMAN Voltage-dependent L-type calcium channel subunit alpha-1D (sprot)

description: A voltage-dependent L-type calcium channel subunit alpha-1D that is encoded in the genome of human.


name: DTX1_HUMAN E3 ubiquitin-protein ligase DTX1 (sprot)

description: An E3 ubiquitin-protein ligase DTX1 that is encoded in the genome of human.


name: TRDMT_HUMAN tRNA (cytosine(38)-C(5))-methyltransferase (sprot)

description: A tRNA (cytosine-5-)-methyltransferase that is encoded in the genome of human.


familial long QT syndrome

description: A hereditary cardiac disease characterized by a prolongation of the QT interval at basal ECG and by a high risk of life-threatening arrhythmias.


keratosis

description: A skin disorder consisting of hypertrophy of the stratum corneum of the skin.


name: MED27_HUMAN Mediator of RNA polymerase II transcription subunit 27 (sprot)

description: A mediator of RNA polymerase II transcription subunit 27 that is encoded in the genome of human.


name: TGON2_HUMAN Trans-Golgi network integral membrane protein 2 (sprot)

description: A trans-Golgi network integral membrane protein 2 that is encoded in the genome of human.


NTNG2_HUMAN Netrin-G2 (sprot)

A netrin-G2 that is encoded in the genome of human.


name: KS6B2_HUMAN Ribosomal protein S6 kinase beta-2 (sprot)

description: A ribosomal protein S6 kinase beta-2 that is encoded in the genome of human.


Ollier disease

description: A rare primary bone dysplasia disorder characterized by the development of multiple mainly unilateral or asymmetrically distributed enchondromas throughout the metaphyses of the long bones.


marantic endocarditis

description: Formation of a non-infectious thrombus, referred to as vegetation, on previously undamaged endocardium. It usually occurs as a complication of connective-tissue diseases and cancers because of the associated hypercoagulable state (see thrombophilia).


name: SOX18_HUMAN Transcription factor SOX-18 (sprot)

description: A transcription factor SOX-18 that is encoded in the genome of human.


bronchiolitis

description: Inflammation of the bronchioles characterized by swelling of the bronchioles and mucus accumulation. It is usually caused by the respiratory syncytial virus and affects children. Signs and symptoms include coughing, wheezing, and shortness of breath.


dysembryoplastic neuroepithelial tumor

description: A benign glial-neuronal neoplasm. It is usually supratentorial, located, generally, in the cortex and occurs in children and young adults with a long-standing history of partial seizures. A histologic hallmark of this tumor is the 'specific glioneuronal element', characterized by columns, made up of bundles of axons, oriented perpendicularly to the cortical surface.B


name: TOPK_HUMAN Lymphokine-activated killer T-cell-originated protein kinase (sprot)

description: A lymphokine-activated killer T-cell-originated protein kinase that is encoded in the genome of human.


name: PKR2_HUMAN Prokineticin receptor 2 (sprot)

description: A prokineticin receptor 2 that is encoded in the genome of human.


name: SIR4_HUMAN NAD-dependent protein lipoamidase sirtuin-4, mitochondrial (sprot)

description: An NAD-dependent protein lipoamidase sirtuin-4, mitochondrial that is encoded in the genome of human.


carcinoma of pharynx

description: A carcinoma that involves the pharynx.


succinylcholine

A quaternary ammonium ion that is the bis-choline ester of succinic acid.


name: GUC1A_HUMAN Guanylyl cyclase-activating protein 1 (sprot)

description: A guanylyl cyclase-activating protein 1 that is encoded in the genome of human.


skin neoplasm

description: A benign or malignant tumor involving the skin. Representative examples of benign skin neoplasms include the benign melanocytic skin nevus, acanthoma, sebaceous adenoma, sweat gland adenoma, lipoma, hemangioma, fibroma, and benign fibrous histiocytoma. Representative examples of malignant skin neoplasms include basal cell carcinoma, squamous cell carcinoma, melanoma, and Kaposi sarcoma.


UTP

A pyrimidine ribonucleoside 5'-triphosphate having uracil as the nucleobase.


spinal muscular atrophy, type 1

description: A severe infantile form of proximal spinal muscular atrophy characterized by severe and progressive muscle weakness and hypotonia resulting from the degeneration and loss of the lower motor neurons in the spinal cord and the brain stem nuclei.


vision disorder

description: Any impairment to the vision.


CORO7_HUMAN Coronin-7 (sprot)

A coronin-7 that is encoded in the genome of human.


A monounsaturated fatty aldehyde that is nonanal that has undergone dehydrogenation to introduce a double bond at any position in the aliphatic chain and in which a hydrogen at position 4 has been replaced by a hydroxy group.


name: FUT7_HUMAN Alpha-(1,3)-fucosyltransferase 7 (sprot)

description: An alpha-(1,3)-fucosyltransferase 7 that is encoded in the genome of human.


name: COAA1_HUMAN Collagen alpha-1(X) chain (sprot)

description: A collagen alpha-1(X) chain that is encoded in the genome of human.


MORC2_HUMAN ATPase MORC2 (sprot)

An ATPase MORC2 that is encoded in the genome of human.


BET1_HUMAN BET1 homolog (sprot)

A BET1 homolog that is encoded in the genome of human.


name: STAG3_HUMAN Cohesin subunit SA-3 (sprot)

description: A cohesin subunit SA-3 that is encoded in the genome of human.


name: PRDM9_HUMAN Histone-lysine N-methyltransferase PRDM9 (sprot)

description: A histone-lysine N-methyltransferase PRDM9 that is encoded in the genome of human.


ITB7_HUMAN Integrin beta-7 (sprot)

An integrin beta-7 that is encoded in the genome of human.


clubfoot

description: The most common congenital deformation of the foot, occurring in 1 of 1,000 live births. The most common form is talipes equinovarus, where the deformed foot is turned downward and inward sharply.


name: HEY2_HUMAN Hairy/enhancer-of-split related with YRPW motif protein 2 (sprot)

description: A hairy/enhancer-of-split related with YRPW motif protein 2 that is encoded in the genome of human.


pyogenic granuloma

description: A disorder of the skin, the oral mucosa, and the gingiva, that usually presents as a solitary polypoid capillary hemangioma often resulting from trauma. It is manifested as an inflammatory response with similar characteristics to those of a granuloma.


aiphanol

A lignan that is (2R)-2,3-dihydro-1,4-benzodioxin-2-ylmethanol which is  substituted by a 2-(3,5-dihydroxyphenyl)ethenyl group at position 6 and a 4-hydroxy-3,5-dimethoxyphenyl group at position 3. It is a stilbenolignan isolated from the seeds of Aiphanes aculeata and exhibits potent inhibitory efficacy against cyclooxygenase-1 and -2 (COX-1 and COX-2).


tedizolid phosphate

A  phosphate monoester resulting from the formal condensation of equimolar amounts of phosphoric acid with the hydroxy group of tedizolid . It is a prodrug of tedizolid, used for the treatment of acute bacterial skin infections caused by certain susceptible bacteria, including Staphylococcus aureus (including methicillin-resistant strains (MRSA) and methicillin-susceptible strains), various Streptococcus species, and Enterococcus faecalis.


name: PRRX2_HUMAN Paired mesoderm homeobox protein 2 (sprot)

description: A paired mesoderm homeobox protein 2 that is encoded in the genome of human.


name: SHC2_HUMAN SHC-transforming protein 2 (sprot)

description: An SHC-transforming protein 2 that is encoded in the genome of human.


CAMPHOR

The (R)- enantiomer of camphor.


name: CRUM3_HUMAN Protein crumbs homolog 3 (sprot)

description: A protein crumbs homolog 3 that is encoded in the genome of human.


semaxanib

An oxindole that is 3-methyleneoxindole in which one of the hydrogens of the methylene group is replaced by a 3,5-dimethylpyrrol-2-yl group.


name: RO60_HUMAN RNA-binding protein RO60 (sprot)

description: An RNA-binding protein RO60 that is encoded in the genome of human.


name: F120B_HUMAN Constitutive coactivator of peroxisome proliferator-activated receptor gamma (sprot)

description: A constitutive coactivator of peroxisome proliferator-activated receptor gamma that is encoded in the genome of human.


cefmetazole

A second-generation cephalosporin antibiotic having N(1)-methyltetrazol-5-ylthiomethyl, {[(cyanomethyl)sulfanyl]acetyl}amino and methoxy side-groups at positions 3, 7beta and 7alpha respectively of the parent cephem bicyclic structure.


name: ASPP1_HUMAN Apoptosis-stimulating of p53 protein 1 (sprot)

description: An apoptosis-stimulating of p53 protein 1 that is encoded in the genome of human.


name: PDIA6_HUMAN Protein disulfide-isomerase A6 (sprot)

description: A protein disulfide-isomerase A6 that is encoded in the genome of human.


homocystinuria

description: An autosomal recessive inherited metabolic disorder caused by mutations in the CBS, MTHFR, MTR, and MTRR genes. It is characterized by abnormalities in the methionine metabolism and is associated with deficiency of cystathionine synthase. It results in the accumulation of homocysteine in the serum. It may affect the cardiovascular, musculoskeletal and the central nervous systems.


name: HXD3_HUMAN Homeobox protein Hox-D3 (sprot)

description: A homeobox protein Hox-D3 that is encoded in the genome of human.


oleuropein

A secoiridoid glycoside that is the methyl ester of 3,4-dihydro-2H-pyran-5-carboxylic acid which is substituted at positions 2, 3, and 4 by hydroxy, ethylidene, and carboxymethyl groups, respectively and in which the anomeric hydroxy group at position 2 has been converted into its beta-D-glucoside and the carboxylic acid moiety of the carboxymethyl substituent has been converted to the corresponding 3,4-dihydroxyphenethyl ester (the 2S,3E,4S stereoisomer). The most important phenolic compound present in olive cultivars.


name: CLC10_HUMAN C-type lectin domain family 10 member A (sprot)

description: A C-type lectin domain family 10 member A that is encoded in the genome of human.


name: B2L11_HUMAN Bcl-2-like protein 11 (sprot)

description: A Bcl-2-like protein 11 that is encoded in the genome of human.


azelastine

A phthalazine compound having an oxo substituent at the 1-position, a 1-methylazepan-4-yl group at the 2-position and a 4-chlorobenzyl substituent at the 4-position.


name: BRNP1_HUMAN BMP/retinoic acid-inducible neural-specific protein 1 (sprot)

description: A BMP/retinoic acid-inducible neural-specific protein 1 that is encoded in the genome of human.


name: MAST3_HUMAN Microtubule-associated serine/threonine-protein kinase 3 (sprot)

description: A microtubule-associated serine/threonine-protein kinase 3 that is encoded in the genome of human.


name: PTPA_HUMAN Serine/threonine-protein phosphatase 2A activator (sprot)

description: A serine/threonine-protein phosphatase 2A regulatory subunit B' that is encoded in the genome of human.


name: Spondyloenchondrodysplasia with immune dysregulation


name: DHTK1_HUMAN 2-oxoadipate dehydrogenase complex component E1 (sprot)

description: A 2-oxoadipate dehydrogenase complex component E1 that is encoded in the genome of human.


name: RFOX1_HUMAN RNA binding protein fox-1 homolog 1 (sprot)

description: An RNA binding protein fox-1 homolog 1 that is encoded in the genome of human.


name: PPM1K_HUMAN Protein phosphatase Mn(2+)-dependent 1K (sprot)

description: A protein phosphatase Mn(2+)-dependent 1K that is encoded in the genome of human.


EXO1_HUMAN Exonuclease 1 (sprot)

An exonuclease 1 that is encoded in the genome of human.


name: CD11B_HUMAN Cyclin-dependent kinase 11B (sprot)

description: A cyclin-dependent kinase 11B that is encoded in the genome of human.


name: YBOX2_HUMAN Y-box-binding protein 2 (sprot)

description: A Y-box-binding protein 2 that is encoded in the genome of human.


name: LCP2_HUMAN Lymphocyte cytosolic protein 2 (sprot)

description: A lymphocyte cytosolic protein 2 that is encoded in the genome of human.


name: BMF_HUMAN Bcl-2-modifying factor (sprot)

description: A Bcl-2-modifying factor that is encoded in the genome of human.


name: GGT1_HUMAN Glutathione hydrolase 1 proenzyme (sprot)

description: A glutathione hydrolase 1 proenzyme that is encoded in the genome of human.


name: SAA2_HUMAN Serum amyloid A-2 protein (sprot)

description: A primate-type serum amyloid A-2 protein that is encoded in the genome of human.


RENR_HUMAN Renin receptor (sprot)

A renin receptor that is encoded in the genome of human.


name: PHLA3_HUMAN Pleckstrin homology-like domain family A member 3 (sprot)

description: A pleckstrin homology-like domain family A member 3 that is encoded in the genome of human.


name: PKR1_HUMAN Prokineticin receptor 1 (sprot)

description: A prokineticin receptor 1 that is encoded in the genome of human.


HEDERAGENIN

A sapogenin that is olean-12-en-28-oic acid substituted by hydroxy groups at positions 3 and 23 (the 3beta stereoisomer).


name: M3K11_HUMAN Mitogen-activated protein kinase kinase kinase 11 (sprot)

description: A mitogen-activated protein kinase kinase kinase 11 that is encoded in the genome of human.


name: SMU1_HUMAN WD40 repeat-containing protein SMU1 (sprot)

description: A WD40 repeat-containing protein SMU1 that is encoded in the genome of human.


name: UBL5_HUMAN Ubiquitin-like protein 5 (sprot)

description: A ubiquitin-like protein 5 that is encoded in the genome of human.


carcinoma of the ampulla of vater

description: A carcinoma arising from the ampulla of Vater. The vast majority of cases are adenocarcinomas. Signs and symptoms include jaundice, abdominal pain, anorexia, nausea, vomiting, and weight loss.


Abnormality of the urinary system

description: An abnormality of the urinary system.


plasma cell neoplasm

description: A clonal proliferation of immunoglobulin-secreting plasma cells. This category includes plasma cell myeloma, plasma cell leukemia, plasmacytoma, monoclonal immunoglobulin deposition disease, and monoclonal gammopathy of undetermined significance.


name: CMTA1_HUMAN Calmodulin-binding transcription activator 1 (sprot)

description: A calmodulin-binding transcription activator 1 that is encoded in the genome of human.


name: RASF2_HUMAN Ras association domain-containing protein 2 (sprot)

description: A Ras association domain-containing protein 2 that is encoded in the genome of human.


name: PPAP_HUMAN Prostatic acid phosphatase (sprot)

description: A prostatic acid phosphatase that is encoded in the genome of human.


name: PLAC8_HUMAN Placenta-specific gene 8 protein (sprot)

description: A placenta-specific gene 8 protein that is encoded in the genome of human.


adolescent idiopathic scoliosis

description: A scoliosis with no known cause arising in adolescent.


name: RM41_HUMAN Large ribosomal subunit protein mL41 (sprot)

description: A large ribosomal subunit protein mL41 that is encoded in the genome of human.


name: SGTA_HUMAN Small glutamine-rich tetratricopeptide repeat-containing protein alpha (sprot)

description: A small glutamine-rich tetratricopeptide repeat-containing protein alpha that is encoded in the genome of human.


NEUS_HUMAN Neuroserpin (sprot)

A neuroserpin that is encoded in the genome of human.


neonatal lupus erythematosus

description: A self-limited skin rash that appears in the neonatal period and usually resolves in four to six months after birth. It is caused by placental transfer of maternal autoantibodies, usually anti-Ro antibody. In a minority of cases, it is associated with congenital heart block, hepatitis, or thrombocytopenia. The mothers of the affected babies may be asymptomatic or suffer from systemic lupus erythematosus, Sjogren's syndrome, or rheumatoid arthritis.


name: P20D1_HUMAN N-fatty-acyl-amino acid synthase/hydrolase PM20D1 (sprot)

description: An N-fatty-acyl-amino acid synthase/hydrolase PM20D1 that is encoded in the genome of human.


almitrine

A triamino-1,3,5-triazine compound having allylamino substituents at the 2- and 4-positions and a 4-(bis(p-fluorophenyl)methyl)-1-piperazinyl group at the 6-position.


essential hypertension

description: Hypertension that presents without an identifiable cause.


name: BRE1A_HUMAN E3 ubiquitin-protein ligase BRE1A (sprot)

description: An E3 ubiquitin-protein ligase BRE1A that is encoded in the genome of human.


Niemann-Pick disease

description: A group of inherited, severe metabolic disorders in which sphingomyelin accumulates in lysosomes in cells. The lysosomes normally transport material through and out of the cell.


name: GCSH_HUMAN Glycine cleavage system H protein, mitochondrial (sprot)

description: A glycine cleavage system H protein, mitochondrial that is encoded in the genome of human.


donepezil

A member of the class of indanones that is 5,6-dimethoxyindan-1-one which is substituted at position 2 by an (N-benzylpiperidin-4-yl)methyl group.


name: ST32A_HUMAN Serine/threonine-protein kinase 32A (sprot)

description: A serine/threonine-protein kinase 32A that is encoded in the genome of human.


name: ZHX1_HUMAN Zinc fingers and homeoboxes protein 1 (sprot)

description: A zinc fingers and homeoboxes protein 1 that is encoded in the genome of human.


atracurium

A diester compound consisting of pentane-1,5-diol with both hydroxyls bearing 3-[1-(3,4-dimethoxybenzyl)-6,7-dimethoxy-2-methyl-3,4-dihydroisoquinolinium-2(1H)-yl]propanoyl groups.


name: PBX2_HUMAN Pre-B-cell leukemia transcription factor 2 (sprot)

description: A pre-B-cell leukemia transcription factor 2 that is encoded in the genome of human.


phosphatidylcholine (17:0/20:3)

A phosphatidylcholine 37:3 in which the fatty acyl groups at positions 1 and 2 are specified as C17:0 and C20:3 respectively.


eccrine carcinoma

description: An adenocarcinoma with eccrine differentiation arising from the sweat glands. It includes the following subtypes: ductal eccrine adenocarcinoma, papillary eccrine carcinoma, and eccrine porocarcinoma.


GM1 gangliosidosis

description: A rare lysosomal storage disorder characterized biochemically by deficient beta-galactosidase activity and clinically by a wide range of variable neurovisceral, ophthalmological and dysmorphic features.


phosphatidylethanolamine (P-16:0/22:1)

A phosphatidylethanolamine P-38:1 in which the 1-alkenyl group contains 16 carbons and no additional double bonds while the acyl group contains 22 carbons and 1 double bond.


name: MZF1_HUMAN Myeloid zinc finger 1 (sprot)

description: A myeloid zinc finger 1 that is encoded in the genome of human.


MARIZOMIB

A salinosporamide in which the core (1R)-6-oxa-2-azabicyclo[3.2.0]heptane-3,7-dione skeleton is substituted at positions 1, 4, and 5 by (1S)-cyclohex-2-en-1-yl(hydroxy)methyl, 2-chloroethyl, and methyl groups, respectively (the 1R,4R,5S diastereoisomer). A potent proteasome inhibitor, it has attracted interest for potential use in the treatment of various cancers.


name: BAHC1_HUMAN BAH and coiled-coil domain-containing protein 1 (sprot)

description: A BAH and coiled-coil domain-containing protein 1 that is encoded in the genome of human.


name: poorly differentiated thyroid gland carcinoma

description: An adenocarcinoma arising from the thyroid gland showing only limited evidence of follicular cell differentiation. Microscopically, the adenocarcinoma cells are arranged in insular, solid, and trabecular patterns. There is associated necrosis, and vascular invasion. The prognosis depends on the tumor stage, complete or partial surgical removal of the tumor, and the degree of response to radioactive iodine therapy (adapted from WHO Tumors of Endocrine Organs, IARC Press, Lyon 2004)


name: CO6A2_HUMAN Collagen alpha-2(VI) chain (sprot)

description: A collagen alpha-2(VI) chain that is encoded in the genome of human.


name: NR2F6_HUMAN Nuclear receptor subfamily 2 group F member 6 (sprot)

description: A nuclear receptor subfamily 2 group F member 6 that is encoded in the genome of human.


CAN5_HUMAN Calpain-5 (sprot)

A calpain-5 that is encoded in the genome of human.


name: S27A6_HUMAN Long-chain fatty acid transport protein 6 (sprot)

description: A long-chain fatty acid transport protein 6 that is encoded in the genome of human.


Melanonychia

description: Brown or black discoloration of the nails.


adenoid hypertrophy

description: An upper respiratory tract disease characterized by the unusual growth of the adenoid tonsil; has symptom snoring, has symptom hyponasality, has symptom otitis media with effusion, has symptom mouth breathing.


name: IFRD1_HUMAN Interferon-related developmental regulator 1 (sprot)

description: An interferon-related developmental regulator 1 that is encoded in the genome of human.


miltefosine

A phospholipid that is the hexadecyl monoester of phosphocholine.


encephalomyelitis

description: Inflammation of the brain and the spinal cord.


name: SHCBP_HUMAN SHC SH2 domain-binding protein 1 (sprot)

description: An SHC SH2 domain-binding protein 1 that is encoded in the genome of human.


name: TRI69_HUMAN E3 ubiquitin-protein ligase TRIM69 (sprot)

description: An E3 ubiquitin-protein ligase TRIM69 that is encoded in the genome of human.


name: DYRK2_HUMAN Dual specificity tyrosine-phosphorylation-regulated kinase 2 (sprot)

description: A dual specificity tyrosine-phosphorylation-regulated kinase 2 that is encoded in the genome of human.


lonidamine

A member of the class of indazoles that is 1H-indazole that is substituted at positions 1 and 3 by 2,4-dichlorobenzyl and carboxy groups, respectively.


METHOXYACETIC ACID

A monocarboxylic acid that is acetic acid in which one of the methyl hydrogens is replaced by a methoxy group.


name: MRP_HUMAN MARCKS-related protein (sprot)

description: A MARCKS-related protein that is encoded in the genome of human.


name: SCND1_HUMAN SCAN domain-containing protein 1 (sprot)

description: A SCAN domain-containing protein 1 that is encoded in the genome of human.


CHKA_HUMAN Choline kinase alpha (sprot)

A choline kinase alpha that is encoded in the genome of human.


name: SEC62_HUMAN Translocation protein SEC62 (sprot)

description: A translocation protein SEC62 that is encoded in the genome of human.


FBF1_HUMAN Fas-binding factor 1 (sprot)

A Fas-binding factor 1 that is encoded in the genome of human.


thymus neoplasm

description: A neoplasm that affects the thymus. Representative examples include thymoma and carcinoma.


MT1L_HUMAN Metallothionein-1L (sprot)

A metallothionein-1L that is encoded in the genome of human.


name: HXB9_HUMAN Homeobox protein Hox-B9 (sprot)

description: A homeobox protein Hox-B9 that is encoded in the genome of human.


UBQL3_HUMAN Ubiquilin-3 (sprot)

A ubiquilin-3 that is encoded in the genome of human.


name: ABEC2_HUMAN C->U-editing enzyme APOBEC-2 (sprot)

description: A C->U-editing enzyme APOBEC-2 that is encoded in the genome of human.


name: CK5P2_HUMAN CDK5 regulatory subunit-associated protein 2 (sprot)

description: A CDK5 regulatory subunit-associated protein 2 that is encoded in the genome of human.


SNX18_HUMAN Sorting nexin-18 (sprot)

A sorting nexin-18 that is encoded in the genome of human.


tyloxapol

A polymeric compound resulting from the reaction of 4-(1,1,3,3-tetramethylbutyl)phenol with formaldehyde to give a chain in which 6-8 molecules are linked together by CH2 groups ortho to the phenolic hydroxy groups, which have then undergone reaction with oxirane to give polyoxyethyleneoxy moieties, Ar(OCH2CH2)xOH, where x = 8-10. A nonionic liquic polymer, it inhibits lipoprotein lipase and hence clearance of triglyceride from the plasma, so is used to induce hyperlipidaemia in test animals. Also used as a surfactant to aid liquefaction and removal of mucus- and pus-containing bronchopulmonary secretions.


Impaired fasting glucose

description: Impaired fasting glucose (IFG) is indicated by a fasting plasma glucose above normal but below the diabetic range. Levels between 110 mg/dl (6.1 mmol/l) to 125 mg/dl (6.9 mmol/l) are diagnostic of IFG.


iron poisoning

description: A heavy metal poisoning that is caused by exposure to iron. Iron toxicity is classified as corrosive or cellular. Ingested iron can cause direct caustic injury to the gastrointestinal mucosa, resulting in nausea, vomiting, abdominal pain, and diarrhea.


name: CBX1_HUMAN Chromobox protein homolog 1 (sprot)

description: A chromobox protein homolog 1 that is encoded in the genome of human.


name: VPS11_HUMAN Vacuolar protein sorting-associated protein 11 homolog (sprot)

description: A vacuolar protein sorting-associated protein 11 that is encoded in the genome of human.


dermatan sulfate

Any of a group of glycosaminoglycans with repeating units consisting of variously sulfated beta1->4-linked L-iduronyl-(alpha1->3)-N-acetyl-D-galactosamine units.


name: PACN3_HUMAN Protein kinase C and casein kinase substrate in neurons protein 3 (sprot)

description: A protein kinase C and casein kinase substrate in neurons protein 3 that is encoded in the genome of human.


name: AT8A2_HUMAN Phospholipid-transporting ATPase IB (sprot)

description: A phospholipid-transporting ATPase IB that is encoded in the genome of human.


PENTADECANOIC ACID

A straight-chain saturated fatty acid containing fifteen-carbon atoms.


name: EF1A2_HUMAN Elongation factor 1-alpha 2 (sprot)

description: An elongation factor 1-alpha 2 that is encoded in the genome of human.


bile duct carcinoma

description: A carcinoma that arises from epithelial cells of the bile duct


DYN1_HUMAN Dynamin-1 (sprot)

A dynamin-1 that is encoded in the genome of human.


name: RHOD_HUMAN Rho-related GTP-binding protein RhoD (sprot)

description: A Rho-related GTP-binding protein RhoD that is encoded in the genome of human.


name: WWP1_HUMAN NEDD4-like E3 ubiquitin-protein ligase WWP1 (sprot)

description: A NEDD4-like E3 ubiquitin-protein ligase WWP1 that is encoded in the genome of human.


TSHR_HUMAN Thyrotropin receptor (sprot)

A thyrotropin receptor that is encoded in the genome of human.


name: PDE3B_HUMAN cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B (sprot)

description: A cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B that is encoded in the genome of human.


efonidipine

A racemate comprising of equimolar amounts of (R)- and (S)-efonidipine. It is a antihypertensive drug and a dual T-type and L-type calcium channel blocker.


Increased susceptibility to fractures

description: An abnormally increased tendency to fractures of bones caused by an abnormal reduction in bone strength that is generally associated with an increased risk of fracture.


name: ZNT9_HUMAN Proton-coupled zinc antiporter SLC30A9, mitochondrial (sprot)

description: A proton-coupled zinc antiporter SLC30A9, mitochondrial that is encoded in the genome of human.


name: BIK_HUMAN Bcl-2-interacting killer (sprot)

description: A Bcl-2-interacting killer that is encoded in the genome of human.


name: NMT2_HUMAN Glycylpeptide N-tetradecanoyltransferase 2 (sprot)

description: A glycylpeptide N-tetradecanoyltransferase 2 that is encoded in the genome of human.


name: TYDP2_HUMAN Tyrosyl-DNA phosphodiesterase 2 (sprot)

description: A tyrosyl-DNA phosphodiesterase 2 that is encoded in the genome of human.


name: CAR16_HUMAN Caspase recruitment domain-containing protein 16 (sprot)

description: A caspase recruitment domain-containing protein 16 that is encoded in the genome of human.


name: PDIA1_HUMAN Protein disulfide-isomerase (sprot)

description: A protein disulfide-isomerase that is encoded in the genome of human.


roxithromycin

Semisynthetic derivative of erythromycin A.


ALLITRIDIN

An organic trisulfide that is trisulfane in which both of the hydrogens are replaced by allyl groups. A component of the essential oil of garlic and a major component of the traditional Chinese medicine allitridium, it exhibits antifungal, antitumour and antioxidant activity


name: FUS_HUMAN RNA-binding protein FUS (sprot)

description: An RNA-binding protein FUS that is encoded in the genome of human.


clobetasol propionate

The 17-O-propionate ester of clobetasol. A potent corticosteroid, it is used to treat various skin disorders, including exzema and psoriasis.


pustulosis palmaris et plantaris

description: A chronic inflammatory disorder that generally occurs in adulthood and is characterized by sterile pustules intermingled with scaly erythemas, vesicles and hyperkeratosis occurring at distinct sites on the palms and soles. It is thought to be an autoimmune disorder precipitated by several factors, including local infection, and smoking.


name: BRE1B_HUMAN E3 ubiquitin-protein ligase BRE1B (sprot)

description: An E3 ubiquitin-protein ligase BRE1B that is encoded in the genome of human.


name: DJC21_HUMAN DnaJ homolog subfamily C member 21 (sprot)

description: A DnaJ homolog subfamily C member 21 that is encoded in the genome of human.


name: PPIP1_HUMAN Proline-serine-threonine phosphatase-interacting protein 1 (sprot)

description: A proline-serine-threonine phosphatase-interacting protein 1 that is encoded in the genome of human.


name: ATG13_HUMAN Autophagy-related protein 13 (sprot)

description: An autophagy-related protein 13 that is encoded in the genome of human.


name: ADA19_HUMAN Disintegrin and metalloproteinase domain-containing protein 19 (sprot)

description: A disintegrin and metalloproteinase domain-containing protein 19 that is encoded in the genome of human.


name: GSHR_HUMAN Glutathione reductase, mitochondrial (sprot)

description: A glutathione reductase, mitochondrial that is encoded in the genome of human.


name: KANK2_HUMAN KN motif and ankyrin repeat domain-containing protein 2 (sprot)

description: A KN motif and ankyrin repeat domain-containing protein 2 that is encoded in the genome of human.


name: MICA1_HUMAN [F-actin]-monooxygenase MICAL1 (sprot)

description: An [F-actin]-monooxygenase MICAL1 that is encoded in the genome of human.


name: RAB8A_HUMAN Ras-related protein Rab-8A (sprot)

description: A Ras-related protein Rab-8A that is encoded in the genome of human.


CD166_HUMAN CD166 antigen (sprot)

A CD166 molecule that is encoded in the genome of human.


name: GAB1_HUMAN GRB2-associated-binding protein 1 (sprot)

description: A GRB2-associated-binding protein 1 that is encoded in the genome of human.


name: TRI48_HUMAN E3 ubiquitin-protein ligase TRIM48 (sprot)

description: An E3 ubiquitin-protein ligase TRIM48 that is encoded in the genome of human.


name: CENPW_HUMAN Centromere protein W (sprot)

description: A centromere protein W that is encoded in the genome of human.


name: PCDC1_HUMAN Protocadherin alpha-C1 (sprot)

description: A protocadherin alpha-C1 that is encoded in the genome of human.


parecoxib

An N-acylsulfonamide resulting from the formal condensation of valdecoxib with propionic acid. It is a prodrug for valdecoxib.


name: SYF1_HUMAN Pre-mRNA-splicing factor SYF1 (sprot)

description: A pre-mRNA-splicing factor SYF1 that is encoded in the genome of human.


name: S22AI_HUMAN Solute carrier family 22 member 18 (sprot)

description: A solute carrier family 22 member 18 that is encoded in the genome of human.


name: MBOA2_HUMAN Lysophospholipid acyltransferase 2 (sprot)

description: A lysophospholipid acyltransferase 2 that is encoded in the genome of human.


dysautonomia

description: An acute or chronic disorder, affecting the sympathetic or parasympathetic nervous system. It can be primary, the result of central nervous system degeneration, or secondary due to diabetes or alcoholism. Patients with the chronic form of this disorder usually have a progressive clinical course and a poor prognosis.


VILI_HUMAN Villin-1 (sprot)

A villin-1 that is encoded in the genome of human.


HPT_HUMAN Haptoglobin (sprot)

A haptoglobin that is encoded in the genome of human.


name: KCNK9_HUMAN Potassium channel subfamily K member 9 (sprot)

description: A potassium channel subfamily K member 9 that is encoded in the genome of human.


name: RENT2_HUMAN Regulator of nonsense transcripts 2 (sprot)

description: A regulator of nonsense transcripts 2 that is encoded in the genome of human.


fructooligosaccharide

carbohydrate-based polymers derived from natural sources that can be utilized by certain gastrointestinal tract bacteria but not by the host animal


cutaneous vasculitis

description: Inflammation of the blood vessel wall characterized by palpable purpura.


Bazex-Dupre-Christol syndrome

description: Bazex-Dupre-Christol syndrome is a rare genodermatosis (hereditary skin disease) with a predisposition to early-onset basal cell carcinomas.


TANC1_HUMAN Protein TANC1 (sprot)

A protein TANC1 that is encoded in the genome of human.


TANC2_HUMAN Protein TANC2 (sprot)

A protein TANC2 that is encoded in the genome of human.


name: SPP2A_HUMAN Signal peptide peptidase-like 2A (sprot)

description: A signal peptide peptidase-like 2A that is encoded in the genome of human.


Microscopic hematuria

description: Microscopic hematuria detected by dipstick or microscopic examination of the urine.


cerebral amyloid angiopathy

description: Hereditary cerebral hemorrhage with amyloidosis (HCHWA) describes a group of rare familial central nervous system disorders characterized by amyloid deposition in the cerebral blood vessels leading to hemorrhagic and non-hemorrhagic strokes, focal neurological deficits, and progressive cognitive decline eventually leading to dementia.


The L-enantiomer of 5-hydroxytryptophan.


name: KI2S2_HUMAN Killer cell immunoglobulin-like receptor 2DS2 (sprot)

description: A killer cell immunoglobulin-like receptor 2DS2 that is encoded in the genome of human.


name: FHL2_HUMAN Four and a half LIM domains protein 2 (sprot)

description: A four and a half LIM domains protein 2 that is encoded in the genome of human.


long QT syndrome 2

description: An autosomal dominant condition caused by mutation(s) in the KCNH2 gene, encoding potassium voltage-gated channel subfamily H member 2. It is characterized by a prolonged QT interval that may result in torsade de pointes, ventricular fibrillation and/or sudden cardiac death.


name: RGPA1_HUMAN Ral GTPase-activating protein subunit alpha-1 (sprot)

description: A Ral GTPase-activating protein subunit alpha-1 that is encoded in the genome of human.


epidemic keratoconjunctivitis

description: Keratoconjunctivitis resulting from infection by adenoviruses.


IDUA_HUMAN Alpha-L-iduronidase (sprot)

An alpha-L-iduronidase that is encoded in the genome of human.


name: SZT2_HUMAN KICSTOR complex protein SZT2 (sprot)

description: A KICSTOR complex protein SZT2 that is encoded in the genome of human.


MUC22_HUMAN Mucin-22 (sprot)

A mucin-22 that is encoded in the genome of human.


name: CAND1_HUMAN Cullin-associated NEDD8-dissociated protein 1 (sprot)

description: A cullin-associated NEDD8-dissociated protein 1 that is encoded in the genome of human.


name: ABT1_HUMAN Activator of basal transcription 1 (sprot)

description: An activator of basal transcription 1 that is encoded in the genome of human.


name: MPP10_HUMAN U3 small nucleolar ribonucleoprotein protein MPP10 (sprot)

description: A U3 small nucleolar ribonucleoprotein protein MPP10 that is encoded in the genome of human.


name: CR1L_HUMAN Complement component receptor 1-like protein (sprot)

description: A complement component receptor 1-like protein that is encoded in the genome of human.


Hypocitraturia

description: A lower than normal concentration of citrate(3-) in the urine.


name: NEK7_HUMAN Serine/threonine-protein kinase Nek7 (sprot)

description: A serine/threonine-protein kinase Nek7 that is encoded in the genome of human.


aceclofenac

A monocarboxylic acid that is the carboxymethyl ester of diclofenac. A non-steroidal anti-inflammatory drug related to diclofenac, it is used in the management of osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis.


name: skeletal dysplasia-intellectual disability syndrome

description: Skeletal dysplasia-intellectual disability syndrome combines skeletal anomalies (short stature, ridging of the metopic suture, fusion of cervical vertebrae, thoracic hemivertebrae, scoliosis, sacral hypoplasia and short middle phalanges) and mild intellectual deficit. It has been described in four male cousins in three sibships. Glucose intolerance was present in three cases, and imperforated anus in one case. Carrier females had minor manifestations (fusion of cervical vertebrae and glucose intolerance). Transmission seems to be X-linked.


name: PICK1_HUMAN PRKCA-binding protein (sprot)

description: A PRKCA-binding protein that is encoded in the genome of human.


RXFP1_HUMAN Relaxin receptor 1 (sprot)

A relaxin receptor 1 that is encoded in the genome of human.


name: CP4AB_HUMAN Cytochrome P450 4A11 (sprot)

description: A cytochrome P450 4A11 that is encoded in the genome of human.


name: PPM1E_HUMAN Protein phosphatase 1E (sprot)

description: A protein phosphatase 1E that is encoded in the genome of human.


GREM1_HUMAN Gremlin-1 (sprot)

A gremlin-1 that is encoded in the genome of human.


chronic atrophic gastritis

description: Atrophic gastritis that is persistent and long-standing.


name: ATL2_HUMAN ADAMTS-like protein 2 (sprot)

description: An ADAMTS-like protein 2 that is encoded in the genome of human.


name: KLF11_HUMAN Krueppel-like factor 11 (sprot)

description: A krueppel-like factor 11 that is encoded in the genome of human.


phenylhydrazine hydrochloride

A hydrochloride resulting from the reaction of equimolar amounts of phenylhydrazine and hydrogen chloride.


name: OTUB2_HUMAN Ubiquitin thioesterase OTUB2 (sprot)

description: A ubiquitin thioesterase OTUB2 that is encoded in the genome of human.


zalcitabine

A pyrimidine 2',3'-dideoxyribonucleoside compound having cytosine as the nucleobase.


name: IL3RB_HUMAN Cytokine receptor common subunit beta (sprot)

description: A cytokine receptor common subunit beta that is encoded in the genome of human.


name: TRI23_HUMAN E3 ubiquitin-protein ligase TRIM23 (sprot)

description: An E3 ubiquitin-protein ligase TRIM23 that is encoded in the genome of human.


name: MINP1_HUMAN Multiple inositol polyphosphate phosphatase 1 (sprot)

description: A multiple inositol polyphosphate phosphatase 1 that is encoded in the genome of human.


hypopharynx squamous cell carcinoma

description: A squamous cell carcinoma that involves the hypopharynx.


DILTIAZEM HYDROCHLORIDE

A hydrochloride salt resulting from the reaction of equimolar amounts of diltiazem and hydrogen chloride. A calcium-channel blocker and vasodilator, it is used in the management of angina pectoris and hypertension.


name: SMBP2_HUMAN DNA-binding protein SMUBP-2 (sprot)

description: A DNA-binding protein SMUBP-2 that is encoded in the genome of human.


name: SYCP1_HUMAN Synaptonemal complex protein 1 (sprot)

description: A synaptonemal complex protein 1 that is encoded in the genome of human.


GON1_HUMAN Progonadoliberin-1 (sprot)

A progonadoliberin-1 that is encoded in the genome of human.


name: COX20_HUMAN Cytochrome c oxidase assembly protein COX20, mitochondrial (sprot)

description: A cytochrome c oxidase assembly protein COX20, mitochondrial that is encoded in the genome of human.


PSPC_HUMAN Surfactant protein C (sprot)

A pulmonary surfactant-associated protein C that is encoded in the genome of human.


name: LYVE1_HUMAN Lymphatic vessel endothelial hyaluronic acid receptor 1 (sprot)

description: A lymphatic vessel endothelial hyaluronic acid receptor 1 that is encoded in the genome of human.


CALR3_HUMAN Calreticulin-3 (sprot)

A calreticulin-3 that is encoded in the genome of human.


name: SC16A_HUMAN Protein transport protein Sec16A (sprot)

description: A protein transport protein Sec16A that is encoded in the genome of human.


SODIUM GLUTAMATE

An optically active form of monosodium glutamate having L-configuration.


CYTM_HUMAN Cystatin-M (sprot)

A cystatin-M that is encoded in the genome of human.


name: CCR1_HUMAN C-C chemokine receptor type 1 (sprot)

description: A C-C chemokine receptor type 1 that is encoded in the genome of human.


dextropropoxyphene

The (1S,2R)-(+)-diastereoisomer of propoxyphene.


Menorrhagia

description: Prolonged and excessive menses at regular intervals in excess of 80 mL or lasting longer than 7 days.


name: NUSAP_HUMAN Nucleolar and spindle-associated protein 1 (sprot)

description: A nucleolar and spindle-associated protein 1 that is encoded in the genome of human.


name: RSPH3_HUMAN Radial spoke head protein 3 homolog (sprot)

description: A radial spoke head protein 3 that is encoded in the genome of human.


idiopathic nephrotic syndrome

description: Nephrotic syndrome for which no cause has been identified.


CLN3_HUMAN Battenin (sprot)

A battenin that is encoded in the genome of human.


oropharyngeal carcinoma

description: Carcinoma, predominantly squamous cell, arising from the epithelial cells of the oropharynx.


name: MAP6_HUMAN Microtubule-associated protein 6 (sprot)

description: A microtubule-associated protein 6 that is encoded in the genome of human.


name: BMP5_HUMAN Bone morphogenetic protein 5 (sprot)

description: A bone morphogenetic protein 5 that is encoded in the genome of human.


name: ANM6_HUMAN Protein arginine N-methyltransferase 6 (sprot)

description: A protein arginine N-methyltransferase 6 that is encoded in the genome of human.


Paget disease

description: A malignant neoplasm composed of large cells with large nuclei, prominent nucleoli, and abundant pale cytoplasm (Paget cells). Paget cell neoplasms include Paget disease of the nipple and extramammary Paget disease which may affect the vulva, penis, anus, skin and scrotum.


calcium acetate

The calcium salt of acetic acid. It is used, commonly as a hydrate, to treat hyperphosphataemia (excess phosphate in the blood) in patients with kidney disease: the calcium ion combines with dietary phosphate to form (insoluble) calcium phosphate, which is excreted in the faeces.


TETRAETHYLAMMONIUM CHLORIDE

A quarternary ammonium chloride salt in which the cation has four ethyl substituents around the central nitrogen.


name: NR1D1_HUMAN Nuclear receptor subfamily 1 group D member 1 (sprot)

description: A nuclear receptor subfamily 1 group D member 1 that is encoded in the genome of human.


cerivastatin

(3R,5S)-3,5-dihydroxyhept-6-enoic acid in which the (7E)-hydrogen is substituted by a 4-(4-fluorophenyl)-2,6-diisopropyl-5-(methoxymethyl)pyridin-3-yl group. Formerly used (as its sodium salt) to lower cholesterol and prevent cardiovascular disease, it was withdrawn from the market worldwide in 2001 following reports of a severe form of muscle toxicity.


distal renal tubular acidosis

description: Distal renal tubular acidosis (dRTA) is a disorder of impaired net acid secretion by the distal tubule characterized by hyperchloremic metabolic acidosis. The classic form is often associated with hypokalemia whereas other forms of acquired dRTA may be associated with hypokalemia, hyperkalemia or normokalemia.


name: GTR9_HUMAN Solute carrier family 2, facilitated glucose transporter member 9 (sprot)

description: A solute carrier family 2, facilitated glucose transporter member 9 that is encoded in the genome of human.


name: CCL15_HUMAN C-C motif chemokine 15 (sprot)

description: A C-C motif chemokine 15 that is encoded in the genome of human.