fructosyltransferase activity

description: Catalysis of the transfer of a fructosyl group to an acceptor molecule, typically another carbohydrate or a lipid.


name: regulation of lipoprotein metabolic process

category: biolink:BiologicalProcess biolink:Occurrent biolink:OntologyClass biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving lipoproteins, any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids.


name: positive regulation of lipoprotein metabolic process

description: Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving lipoproteins, any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids.


name: negative regulation of lipoprotein metabolic process

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving lipoproteins, any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids.


name: low-density lipoprotein particle receptor binding

category: biolink:MolecularActivity biolink:Occurrent biolink:OntologyClass biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: Binding to a low-density lipoprotein receptor.


depsipeptide metabolic process

description: The chemical reactions and pathways involving depsipeptides, a linear or cyclic compound composed of both amino acids and hydroxy acids in peptide and ester bonds respectively.


depsipeptide catabolic process

description: The chemical reactions and pathways resulting in the breakdown of depsipeptides, a linear or cyclic compound composed of both amino acids and hydroxy acids in peptide and ester bonds respectively.


depsipeptide biosynthetic process

description: The chemical reactions and pathways resulting in the formation of depsipeptides, a linear or cyclic compound composed of both amino acids and hydroxy acids in peptide and ester bonds respectively.


regulation of phagocytosis

description: Any process that modulates the frequency, rate or extent of phagocytosis, the process in which phagocytes engulf external particulate material.


negative regulation of phagocytosis

description: Any process that stops, prevents, or reduces the frequency, rate or extent of phagocytosis.


positive regulation of phagocytosis

description: Any process that activates or increases the frequency, rate or extent of phagocytosis.


regulation of neurogenesis

description: Any process that modulates the frequency, rate or extent of neurogenesis, the generation of cells in the nervous system.


negative regulation of neurogenesis

description: Any process that stops, prevents, or reduces the frequency, rate or extent of neurogenesis, the generation of cells within the nervous system.


positive regulation of neurogenesis

description: Any process that activates or increases the frequency, rate or extent of neurogenesis, the generation of cells within the nervous system.


regulation of axonogenesis

description: Any process that modulates the frequency, rate or extent of axonogenesis, the generation of an axon, the long process of a neuron.


negative regulation of axonogenesis

description: Any process that stops, prevents, or reduces the frequency, rate or extent of axonogenesis.


positive regulation of axonogenesis

description: Any process that activates or increases the frequency, rate or extent of axonogenesis.


regulation of dendrite development

description: Any process that modulates the frequency, rate or extent of dendrite development.


name: negative regulation of dendrite morphogenesis

description: Any process that stops, prevents, or reduces the frequency, rate or extent of dendrite morphogenesis.


name: positive regulation of dendrite morphogenesis

description: Any process that activates or increases the frequency, rate or extent of dendrite morphogenesis.


regulation of immune response

description: Any process that modulates the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.


negative regulation of immune response

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.


positive regulation of immune response

description: Any process that activates or increases the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.


RNA destabilization

description: Any process that decreases the stability of an RNA molecule, making it more vulnerable to degradative processes.


dopamine receptor binding

description: Binding to a dopamine receptor.


name: ortho-trichlorophenol reductive dehalogenase activity

description: Catalysis of the reaction: 2,4,6-trichlorophenol + 2 H+ + 2 e- = 2,4-dichlorophenol + HCl.


galactose uniporter activity

description: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: galactose (out) = galactose(in).


cocaine metabolic process

description: The chemical reactions and pathways involving cocaine, an alkaloid obtained from the dried leaves of the shrub Erythroxylon coca. It is a cerebral stimulant and narcotic.


cocaine catabolic process

description: The chemical reactions and pathways resulting in the breakdown of cocaine, an alkaloid obtained from the dried leaves of the shrub Erythroxylon coca. It is a cerebral stimulant and narcotic.


name: advanced glycation end-product receptor activity

description: Combining with advanced glycation end-products and transmitting the signal to initiate a change in cell activity. Advanced glycation end-products (AGEs) form from a series of chemical reactions after an initial glycation event (a non-enzymatic reaction between reducing sugars and free amino groups of proteins).


RAGE receptor binding

description: Binding to a RAGE receptor, the receptor for advanced glycation end-products.


detoxification of mercury ion

description: Any process that reduce or remove the toxicity of mercuric ion. These include transport of mercury away from sensitive areas and to compartments or complexes whose purpose is sequestration of mercury ion and/or reduction of mercury ion (Hg[II]) to metallic mercury (Hg[0]).


sequestering of mercury

description: The process of binding or confining toxic mercury ions or atoms such that they are separated from sensitive components of a biological system.


regulation of biological process

description: Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.


regulation of catalytic activity

description: Any process that modulates the activity of an enzyme.


regulation of viral process

description: Any process that modulates the rate or extent of the viral life cycle, the set of processes by which a virus reproduces and spreads among hosts.


regulation of developmental process

description: Any process that modulates the frequency, rate or extent of development, the biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).


regulation of cellular process

description: Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.


regulation of behavior

description: Any process that modulates the frequency, rate or extent of behavior, the internally coordinated responses (actions or inactions) of whole living organisms (individuals or groups) to internal or external stimuli.


regulation of insulin secretion

description: Any process that modulates the frequency, rate or extent of the regulated release of insulin.


thymidylate synthase (FAD) activity

description: Catalysis of the reaction: 5,10-methylenetetrahydrofolate + dUMP + NADPH + H+ = dTMP + tetrahydrofolate + NADP+.


activated T cell proliferation

description: The expansion of a T cell population following activation by an antigenic stimulus.


cocaine biosynthetic process

description: The chemical reactions and pathways resulting in the formation of cocaine, an alkaloid obtained from the dried leaves of the shrub Erythroxylon coca. It is a cerebral stimulant and narcotic.


monoatomic ion homeostasis

description: Any process involved in the maintenance of an internal steady state of monoatomic ions within an organism or cell. Monatomic ions (also called simple ions) are ions consisting of exactly one atom.


circadian sleep/wake cycle, sleep

description: The part of the circadian sleep/wake cycle where the organism is asleep.


name: regulation of synapse structure or activity

description: Any process that modulates the physical form or the activity of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell).


name: modulation of chemical synaptic transmission

description: Any process that modulates the frequency or amplitude of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse. Amplitude, in this case, refers to the change in postsynaptic membrane potential due to a single instance of synaptic transmission.


name: negative regulation of synaptic transmission

description: Any process that stops, prevents, or reduces the frequency, rate or extent of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse.


name: positive regulation of synaptic transmission

description: Any process that activates or increases the frequency, rate or extent of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse.


regulation of synapse organization

description: Any process that modulates the physical form of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell).


synapse organization

description: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell).


diazepam binding

description: Binding to diazepam, one of the most widely used benzodiazepine drugs. It is used as an anti-anxiety-hypnotic agent and has the proprietary name Valium.


name: regulation of steroid biosynthetic process

description: Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus.


GABA receptor binding

description: Binding to a gamma-aminobutyric acid (GABA, 4-aminobutyrate) receptor.


name: regulation of acyl-CoA biosynthetic process

description: Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of acyl-CoA.


epothilone metabolic process

description: The chemical reactions and pathways involving epothilone, a drug obtained from the myxobacteria Sporangium cellulosum that interferes with cell division. Some epothilones are being studied as treatments for cancer.


epothilone biosynthetic process

description: The chemical reactions and pathways resulting in the formation of epothilone, a drug obtained from the myxobacteria Sporangium cellulosum that interferes with cell division. Some epothilones are being studied as treatments for cancer.


phosphoserine residue binding

description: Binding to a phosphorylated serine residue within a protein.


phosphothreonine residue binding

description: Binding to a phosphorylated threonine residue within a protein.


coagulation

description: The process in which a fluid solution, or part of it, changes into a solid or semisolid mass.


regulation of coagulation

description: Any process that modulates the frequency, rate or extent of coagulation, the process in which a fluid solution, or part of it, changes into a solid or semisolid mass.


negative regulation of coagulation

description: Any process that stops, prevents, or reduces the frequency, rate or extent of coagulation.


positive regulation of coagulation

description: Any process that activates or increases the frequency, rate or extent of coagulation.


protein stabilization

description: Any process involved in maintaining the structure and integrity of a protein and preventing it from degradation or aggregation.


peptide stabilization

description: Any process involved in maintaining the structure and integrity of a peptide and preventing it from being degraded.


peptide antigen stabilization

description: Any process involved in maintaining the structure and integrity of a peptide antigen and preventing it from being degraded.


ice binding

description: Binding to ice, water reduced to the solid state by cold temperature. It is a white or transparent colorless substance, crystalline, brittle, and viscoidal.


response to freezing

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a freezing stimulus, temperatures below 0 degrees Celsius.


name: defense response to Gram-negative bacterium

description: Reactions triggered in response to the presence of a Gram-negative bacterium that act to protect the cell or organism.


name: defense response to Gram-positive bacterium

description: Reactions triggered in response to the presence of a Gram-positive bacterium that act to protect the cell or organism.


name: male-specific defense response to bacterium

description: A set of reactions, specific to males, that are triggered in response to the presence of a bacterium that act to protect the cell or organism.


defense response to fungus

description: Reactions triggered in response to the presence of a fungus that act to protect the cell or organism.


name: pyruvate transmembrane transporter activity

description: Enables the transfer of pyruvate, 2-oxopropanoate, from one side of a membrane to the other.


name: molybdenum incorporation via L-cysteinyl copper sulfido molybdopterin cytosine dinucleotide

description: The incorporation of molybdenum into a protein by L-cysteinyl copper sulfido molybdopterin cytosine dinucleotide.


name: iron incorporation into iron-sulfur cluster via tris-L-cysteinyl S-adenosylmethion-N,O-diyl tetrairon tetrasulfide

description: The incorporation of iron into a 4Fe-4S iron-sulfur cluster via tris-L-cysteinyl S-adenosylmethion-N,O-diyl tetrairon tetrasulfide.


name: iron incorporation into iron-sulfur cluster via tris-L-cysteinyl L-arginyl diiron disulfide

description: The incorporation of iron into a 4Fe-4S iron-sulfur cluster via tris-L-cysteinyl L-arginyl diiron disulfide.


description: The methylation of 5-hydroxy-L-lysine to form peptidyl-N6,N6,N6-trimethyl-5-hydroxy-L-lysine.


cell adhesion molecule binding

description: Binding to a cell adhesion molecule.


extracellular matrix binding

description: Binding to a component of the extracellular matrix.


name: peptidyl-N6,N6,N6-trimethyl-lysine hydroxylation to peptidyl-N6,N6,N6-trimethyl-5-hydroxy-L-lysine

description: The hydroxylation of peptidyl-N6,N6,N6-trimethyl-L-lysine to form peptidyl-N6,N6,N6-trimethyl-5-hydroxy-L-lysine.


name: copper incorporation via L-cysteinyl copper sulfido molybdopterin cytosine dinucleotide

description: The incorporation of copper into a protein by L-cysteinyl copper sulfido molybdopterin cytosine dinucleotide.


S-adenosylmethionine catabolic process

description: The chemical reactions and pathways resulting in the breakdown of S-adenosylmethionine, S-(5'-adenosyl)-L-methionine, an important intermediate in one-carbon metabolism.


peptidyl-selenocysteine modification

description: The modification of peptidyl-selenocysteine.


teichuronic acid biosynthetic process

description: The chemical reactions and pathways resulting in the formation of teichuronic acid, a polymer containing chains of uronic acids and N-acetylglucosamine found in the cell wall, membrane or capsule of Gram-positive bacteria.


teichuronic acid metabolic process

description: The chemical reactions and pathways involving teichuronic acid, a polymer containing chains of uronic acids and N-acetylglucosamine found in the cell wall, membrane or capsule of Gram-positive bacteria.


progesterone receptor signaling pathway

category: biolink:Pathway biolink:OntologyClass biolink:BiologicalProcess biolink:Occurrent biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: A nuclear receptor-mediated signaling pathway initiated by a progesterone binding to an intracellular receptor of the nuclear receptor protein family, and ending with regulation of a downstream cellular process, e.g. transcription.


name: regulation of calcium-mediated signaling

description: Any process that modulates the frequency, rate or extent of calcium-mediated signaling, the process in which a cell uses calcium ions to convert an extracellular signal into a response.


name: negative regulation of calcium-mediated signaling

description: Any process that stops, prevents, or reduces the frequency, rate or extent of calcium-mediated signaling.


name: positive regulation of calcium-mediated signaling

description: Any process that activates or increases the frequency, rate or extent of calcium-mediated signaling.


name: antigen receptor-mediated signaling pathway

description: The series of molecular signals initiated by the cross-linking of an antigen receptor on a B or T cell.


T cell receptor signaling pathway

description: The series of molecular signals initiated by the cross-linking of an antigen receptor on a T cell.


B cell receptor signaling pathway

description: The series of molecular signals initiated by the cross-linking of an antigen receptor on a B cell.


name: regulation of antigen receptor-mediated signaling pathway

description: Any process that modulates the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B- or T cell.


name: regulation of B cell receptor signaling pathway

description: Any process that modulates the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B cell.


name: regulation of T cell receptor signaling pathway

description: Any process that modulates the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a T cell.


name: positive regulation of antigen receptor-mediated signaling pathway

description: Any process that activates or increases the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B- or T cell.


name: negative regulation of antigen receptor-mediated signaling pathway

description: Any process that stops, prevents, or reduces the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B- or T cell.


name: negative regulation of B cell receptor signaling pathway

description: Any process that stops, prevents, or reduces the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B cell.


name: negative regulation of T cell receptor signaling pathway

description: Any process that stops, prevents, or reduces the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a T cell.


name: positive regulation of B cell receptor signaling pathway

description: Any process that activates or increases the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B cell.


name: positive regulation of T cell receptor signaling pathway

description: Any process that activates or increases the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a T cell.


regulation of T cell activation

description: Any process that modulates the frequency, rate or extent of T cell activation.


regulation of B cell activation

description: Any process that modulates the frequency, rate or extent of B cell activation.


regulation of cell activation

description: Any process that modulates the frequency, rate or extent of cell activation, the change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand.


negative regulation of cell activation

description: Any process that stops, prevents, or reduces the frequency, rate or extent of cell activation.


positive regulation of cell activation

description: Any process that activates or increases the frequency, rate or extent of activation.


name: negative regulation of T cell activation

description: Any process that stops, prevents, or reduces the frequency, rate or extent of T cell activation.


name: negative regulation of B cell activation

description: Any process that stops, prevents, or reduces the frequency, rate or extent of B cell activation.


name: positive regulation of T cell activation

description: Any process that activates or increases the frequency, rate or extent of T cell activation.


name: positive regulation of B cell activation

description: Any process that activates or increases the frequency, rate or extent of B cell activation.


white fat cell differentiation

description: The process in which a relatively unspecialized cell acquires specialized features of a white adipocyte, an animal connective tissue cell involved in energy storage. White adipocytes have cytoplasmic lipids arranged in a unique vacuole.


brown fat cell differentiation

description: The process in which a relatively unspecialized cell acquires specialized features of a brown adipocyte, an animal connective tissue cell involved in adaptive thermogenesis. Brown adipocytes contain multiple small droplets of triglycerides and a high number of mitochondria.


nervous system process

description: A organ system process carried out by any of the organs or tissues of neurological system.


regulation of body fluid levels

description: Any process that modulates the levels of body fluids.


multicellular organismal movement

description: Any physiological process involved in changing the position of a multicellular organism or an anatomical part of a multicellular organism.


musculoskeletal movement

description: The movement of an organism or part of an organism using mechanoreceptors, the nervous system, striated muscle and/or the skeletal system.


voluntary musculoskeletal movement

description: The movement of an organism or part of an organism using mechanoreceptors, the nervous system, striated muscle and/or the skeletal system that can be controlled at will.


name: musculoskeletal movement, spinal reflex action

description: Involuntary movement caused by the application of a stimulus to an organism and a subsequent movement. The signal processing of this movement takes place in the spinal cord.


name: neuromuscular process controlling posture

description: Any process in which an organism voluntarily modulates its posture, the alignment of its anatomical parts.


name: neuromuscular process controlling balance

description: Any process that an organism uses to control its balance, the orientation of the organism (or the head of the organism) in relation to the source of gravity. In humans and animals, balance is perceived through visual cues, the labyrinth system of the inner ears and information from skin pressure receptors and muscle and joint receptors.


endocrine process

description: The process that involves the secretion of or response to endocrine hormones. An endocrine hormone is a hormone released into the circulatory system.


determination of sensory modality

description: The determination of the type or quality of a sensation. Sensory modalities include touch, thermal sensation, visual sensation, auditory sensation and pain.


determination of stimulus location

description: The determination of where on the body surface, within the body or in the environment a stimulus originates.


determination of stimulus intensity

description: The determination of the perceived strength of a sensory stimulus.


cognition

description: The operation of the mind by which an organism becomes aware of objects of thought or perception; it includes the mental activities associated with thinking, learning, and memory.


name: multicellular organismal-level water homeostasis

description: A chemical homeostatic process involved in the maintenance of a steady state level of water within extracellular body fluids, such as blood, xylem or phloem, of a multicellular organism. This is distinct from maintenance of cellular homeostasis, which occurs within a cell.


intestinal absorption

description: A process in which nutrients are taken up from the contents of the intestine.


sensory processing

description: Any neural process required for an organism to sense and interpret the dimensions of a sensory experience: modality, location, intensity and affect.


determination of affect

description: Any process in which an emotional response is associated with a particular sensory stimulation.


response to stimulus

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism.


cobalt ion binding

description: Binding to a cobalt ion (Co2+).


nitrile metabolic process

description: The chemical reactions and pathways involving nitriles, an organic compound containing trivalent nitrogen attached to one carbon atom. The nitriles are named with reference to the acids produced by their decomposition; for example, hydrocyanic acid is formic nitrile, and methyl cyanide is acetic nitrile.


nitrile catabolic process

description: The chemical reactions and pathways resulting in the breakdown of a nitrile, an organic compound containing trivalent nitrogen attached to one carbon atom.


leukocyte migration

description: The movement of a leukocyte within or between different tissues and organs of the body.


leukocyte tethering or rolling

description: Transient adhesive interactions between leukocytes and endothelial cells lining blood vessels. Carbohydrates on circulating leukocytes bind selectins on the vessel wall causing the leukocytes to slow down and roll along the inner surface of the vessel wall. During this rolling motion, transitory bonds are formed and broken between selectins and their ligands. Typically the first step in cellular extravasation (the movement of leukocytes out of the circulatory system, towards the site of tissue damage or infection).


leukocyte adhesive activation

description: The activation of loosely bound or rolling leukocytes by signals displayed on blood vessel endothelial cells, which is typically the second step in cellular extravasation.


leukocyte activation-dependent arrest

description: The formation of an integrin-dependent strong adhesive bond between leukocytes and blood vessel endothelial cells which is dependent on prior activation of the leukocyte and leads to the firm attachment of the leukocyte to the endothelial surface, typically the third step in cellular extravasation.


diapedesis

description: The passage of a leukocyte between the tight junctions of endothelial cells lining blood vessels, typically the fourth and final step of cellular extravasation.


neuromuscular process

description: Any process pertaining to the functions of the nervous and muscular systems of an organism.


name: detection of stimulus involved in sensory perception

description: The series of events involved in sensory perception in which a sensory stimulus is received and converted into a molecular signal.


name: detection of chemical stimulus involved in sensory perception

description: The series of events in which a chemical stimulus is received and converted into a molecular signal as part of sensory perception.


name: detection of light stimulus involved in visual perception

description: The series of events involved in visual perception in which a light stimulus is received and converted into a molecular signal.


sensory perception of taste

description: The series of events required for an organism to receive a gustatory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Gustation involves the direct detection of chemical composition, usually through contact with chemoreceptor cells. This is a neurological process.


name: detection of mechanical stimulus involved in sensory perception of sound

description: The series of events involved in the perception of sound vibration in which the vibration is received and converted into a molecular signal.


name: detection of chemical stimulus involved in sensory perception of smell

description: The series of events involved in the perception of smell in which an olfactory chemical stimulus is received and converted into a molecular signal.


name: detection of chemical stimulus involved in sensory perception of taste

description: The series of events involved in the perception of taste in which a gustatory chemical stimulus is received and converted into a molecular signal.


sensory perception of bitter taste

description: The series of events required to receive a bitter taste stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.


sensory perception of salty taste

description: The series of events required to receive a salty taste stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.


sensory perception of sour taste

description: The series of events required to receive a sour taste stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.


sensory perception of sweet taste

description: The series of events required to receive a sweet taste stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.


sensory perception of umami taste

description: The series of events required to receive an umami taste stimulus, convert it to a molecular signal, and recognize and characterize the signal. Umami taste is the savory taste of meats and other foods that are rich in glutamates. This is a neurological process.


positive chemotaxis

description: The directed movement of a motile cell or organism towards a higher concentration of a chemical.


negative chemotaxis

description: The directed movement of a motile cell or organism towards a lower concentration of a chemical.


regulation of chemotaxis

description: Any process that modulates the frequency, rate or extent of the directed movement of a motile cell or organism in response to a specific chemical concentration gradient.


positive regulation of chemotaxis

description: Any process that activates or increases the frequency, rate or extent of the directed movement of a motile cell or organism in response to a specific chemical concentration gradient.


negative regulation of chemotaxis

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a motile cell or organism in response to a specific chemical concentration gradient.


regulation of negative chemotaxis

description: Any process that modulates the frequency, rate or extent of the directed movement of a motile cell or organism towards a lower concentration in a concentration gradient of a specific chemical.


name: positive regulation of negative chemotaxis

description: Any process that activates or increases the frequency, rate or extent of the directed movement of a motile cell or organism towards a lower concentration in a concentration gradient of a specific chemical.


name: negative regulation of negative chemotaxis

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a motile cell or organism towards a lower concentration in a concentration gradient of a specific chemical.


regulation of positive chemotaxis

description: Any process that modulates the frequency, rate or extent of the directed movement of a motile cell or organism towards a higher concentration in a concentration gradient of a specific chemical.


name: positive regulation of positive chemotaxis

description: Any process that activates or increases the frequency, rate or extent of the directed movement of a motile cell or organism towards a higher concentration in a concentration gradient of a specific chemical.


name: negative regulation of positive chemotaxis

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a motile cell or organism towards a higher concentration in a concentration gradient of a specific chemical.


induction of negative chemotaxis

description: Any process that initiates the directed movement of a motile cell or organism towards a lower concentration in a concentration gradient of a specific chemical.


induction of positive chemotaxis

description: Any process that initiates the directed movement of a motile cell or organism towards a higher concentration in a concentration gradient of a specific chemical.


pigment cell differentiation

description: The process in which a relatively unspecialized cell acquires the specialized features of a pigmented cell, such as a melanocyte.


name: regulation of pigment cell differentiation

description: Any process that modulates the frequency, rate or extent of pigmented cell differentiation.


early stripe melanocyte differentiation

description: The process in which a relatively unspecialized cell acquires the specialized features of an early stripe melanocyte (ESM). In zebrafish, ESMs develop during the first phase (2-3 weeks of development) of the larva to adult transition (2-4 weeks of development).


late stripe melanocyte differentiation

description: The process in which a relatively unspecialized cell acquires the specialized features of a late stripe melanocyte (LSM). In zebrafish, LSMs develop during the second phase (3-4 weeks of development) of the larva-to-adult transition (2-4 weeks of development).


iridophore differentiation

description: The process in which a relatively unspecialized cell acquires the specialized features of an iridophore. Iridophores are pigment cells derived from the neural crest. They contain guanidine or other purine crystals deposited in stacks called reflecting platets or iridisomes. This gives them a silver, gold, or iridescent appearance.


xanthophore differentiation

description: The process in which a relatively unspecialized cell acquires the specialized features of a xanthophore cell. Xanthophores are pigment cells derived from the neural crest. They contain pteridine and/or carotenoid pigments in structures called pterinosomes or xanthosomes. This makes them yellow to orange in appearance.


name: regulation of iridophore differentiation

description: Any process that modulates the frequency, rate or extent of iridophore differentiation.


name: regulation of xanthophore differentiation

description: Any process that modulates the frequency, rate or extent of xanthophore differentiation.


name: regulation of early stripe melanocyte differentiation

description: Any process that modulates the frequency, rate or extent of early stripe melanocyte differentiation.


name: regulation of late stripe melanocyte differentiation

description: Any process that modulates the frequency, rate or extent of late stripe melanocyte differentiation.


name: negative regulation of pigment cell differentiation

description: Any process that stops, prevents, or reduces the frequency, rate or extent of pigment cell differentiation.


name: positive regulation of pigment cell differentiation

description: Any process that activates or increases the frequency, rate or extent of pigment cell differentiation.


name: negative regulation of iridophore differentiation

description: Any process that stops, prevents, or reduces the frequency, rate or extent of iridophore differentiation.


name: negative regulation of xanthophore differentiation

description: Any process that stops, prevents, or reduces the frequency, rate or extent of xanthophore differentiation.


name: positive regulation of iridophore differentiation

description: Any process that activates or increases the frequency, rate or extent of iridophore differentiation.


name: positive regulation of xanthophore differentiation

description: Any process that activates or increases the frequency, rate or extent of xanthophore differentiation.


name: negative regulation of early stripe melanocyte differentiation

description: Any process that stops, prevents, or reduces the frequency, rate or extent of early stripe melanocyte differentiation.


name: positive regulation of early stripe melanocyte differentiation

description: Any process that activates or increases the frequency, rate or extent of early stripe melanocyte differentiation.


name: negative regulation of late stripe melanocyte differentiation

description: Any process that stops, prevents, or reduces the frequency, rate or extent of late stripe melanocyte differentiation.


name: positive regulation of late stripe melanocyte differentiation

description: Any process that activates or increases the frequency, rate or extent of late stripe melanocyte differentiation.


name: sensory perception of temperature stimulus

description: The series of events required for an organism to receive a sensory temperature stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.


name: sensory perception of electrical stimulus

description: The series of events required for an organism to receive a sensory electrical stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.


sensory perception of light stimulus

description: The series of events required for an organism to receive a sensory light stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.


name: sensory perception of mechanical stimulus

description: The series of events required for an organism to receive a sensory mechanical stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.


thermoception

description: The series of events required for an organism to receive a temperature stimulus, convert it to a molecular signal, and recognize and characterize the signal. Thermoception in larger animals is mainly done in the skin; mammals have at least two types of sensor, for detecting heat (temperatures above body temperature) and cold (temperatures below body temperature).


electroception

description: The series of events required for an organism to receive an electrical stimulus, convert it to a molecular signal, and recognize and characterize the signal. Many fish possess an electroception sense; for example, the electric eel uses low voltage pulses of electricity for navigation and prey location.


equilibrioception

description: The series of events required for an organism to receive an orientational stimulus, convert it to a molecular signal, and recognize and characterize the signal. Equilibrioception refers to a combination of processes by which an organism can perceive its orientation with respect to gravity. In animals, stimuli come from labyrinth system of the inner ears, monitoring the direction of motion; visual stimuli, with information on orientation and motion; pressure receptors, which tell the organism which body surfaces are in contact with the ground; and proprioceptive cues, which report which parts of the body are in motion.


magnetoreception

description: The series of events required for an organism to receive a stimulus relating to a magnetic field, convert it to a molecular signal, and recognize and characterize the signal. Stimuli may be chemical, mechanical or electrical and interpreting these stimuli allows an organism to determine the orientation of a magnetic field. Magnetoreception also involves the perception of light; birds cannot orient without the presence of short wavelength (blue/green) light.


echolocation

description: Echolocation is the method used by some animals (e.g. bats, dolphins and some whales) to determine the location of something by measuring the time it takes for an echo to return from it. These animals emit sound waves and listen for the echo, calculating the distance to the object from the time lapse between sound emission and the echo returning.


name: detection of temperature stimulus involved in thermoception

description: The series of events in which a temperature stimulus is received and converted into a molecular signal as part of thermoception.


name: detection of temperature stimulus involved in sensory perception

description: The series of events in which a temperature stimulus is received and converted into a molecular signal as part of sensory perception.


name: detection of light stimulus involved in sensory perception

description: The series of events in which a light stimulus is received by a cell and converted into a molecular signal as part of the sensory perception of light.


name: detection of electrical stimulus involved in sensory perception

description: The series of events in which an electrical stimulus is received by a cell and converted into a molecular signal as part of sensory perception.


name: detection of electrical stimulus involved in electroception

description: The series of events that contribute to electroception in which an electrical stimulus is received and converted into a molecular signal.


name: detection of temperature stimulus involved in sensory perception of pain

description: The series of events involved in the perception of pain in which a temperature stimulus is received and converted into a molecular signal.


name: detection of mechanical stimulus involved in sensory perception of pain

description: The series of events involved in the perception of pain in which a mechanical stimulus is received and converted into a molecular signal.


name: detection of electrical stimulus involved in sensory perception of pain

description: The series of events that contribute to the perception of pain in which an electrical stimulus is received and converted into a molecular signal.


name: detection of chemical stimulus involved in sensory perception of pain

description: The series of events involved in the perception of pain in which a chemical stimulus is received and converted into a molecular signal.


name: detection of chemical stimulus involved in magnetoreception

description: The series of events involved in magnetoception in which a chemical stimulus is received and converted into a molecular signal. It is believed that organisms such as birds and salamanders interpret product ratios in chemical reactions which involve transitions between different spin states.


name: detection of electrical stimulus involved in magnetoreception

description: The series of events that contribute to magnetoception in which an electrical stimulus is received and converted into a molecular signal. The stimulus is in the form of an induced electric field resulting from movement in a magnetic field.


name: detection of mechanical stimulus involved in magnetoreception

description: The series of events involved in magnetoception in which a mechanical stimulus is received and converted into a molecular signal. The stimulus is in the form of torque on particles such as magnetite which respond to a magnetic field.


name: detection of mechanical stimulus involved in echolocation

description: The series of events involved in echolocation in which a mechanical stimulus is received and converted into a molecular signal. The stimulus is in the form of a reflected sound wave (an echo), which the organism uses to determine the distance to the object that reflected the sound wave.


name: detection of mechanical stimulus involved in equilibrioception

description: The series of events involved in equilibrioception in which a mechanical stimulus is received and converted into a molecular signal. During equilibrioception, mechanical stimuli may be in the form of input from pressure receptors or from the labyrinth system of the inner ears.


name: detection of mechanical stimulus involved in sensory perception

description: The series of events in which a mechanical stimulus is received and converted into a molecular signal as part of sensory perception.


sensory perception of touch

description: The series of events required for an organism to receive a touch stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. The perception of touch in animals is mediated by mechanoreceptors in the skin and mucous membranes and is the sense by which contact with objects gives evidence as to certain of their qualities. Different types of touch can be perceived (for example, light, coarse, pressure and tickling) and the stimulus may be external or internal (e.g. the feeling of a full stomach).


name: detection of mechanical stimulus involved in sensory perception of touch

description: The series of events involved in the perception of touch in which a mechanical stimulus is received and converted into a molecular signal.


name: magnetoreception by sensory perception of chemical stimulus

description: The series of events required for an organism to receive a chemical stimulus relating to a magnetic field, convert it to a molecular signal, and recognize and characterize the signal. It is believed that organisms such as birds and salamanders use a 'chemical compass': chemical reactions that involve transitions between different spin states can be influenced by magnetic fields and by detecting the different product ratios, these organisms can perceive the direction of the magnetic field. The mechanism by which this is detected is not certain but it may also involve light stimuli.


name: magnetoreception by sensory perception of electrical stimulus

description: The series of events required for an organism to receive an electrical stimulus relating to a magnetic field, convert it to a molecular signal, and recognize and characterize the signal. Movement in a magnetic field results in an induced electric field, which can be perceived by organisms such as elasmobranch fish.


name: magnetoreception by sensory perception of mechanical stimulus

description: The series of events required for an organism to receive a mechanical stimulus relating to a magnetic field, convert it to a molecular signal, and recognize and characterize the signal. A magnetic field exerts a torque on a ferromagnetic material (e.g. magnetite) or on a material with diamagnetic anisotropy; organisms that can detect this torque can use it to determine the orientation of the magnetic field.


name: detection of light stimulus involved in magnetoreception

description: The series of events involved in magnetoception in which a light stimulus is received and converted into a molecular signal. Downstream processing of the light information in addition to other sensory data allows organisms to perceive the orientation of a magnetic field.


detection of electrical stimulus

description: The series of events by which an electrical stimulus is received and converted into a molecular signal.


detection of mechanical stimulus

description: The series of events by which a mechanical stimulus is received and converted into a molecular signal.


peptidyl-serine sulfation

description: The sulfation of peptidyl-serine to form peptidyl-O-sulfo-L-serine.


peptidyl-threonine sulfation

description: The sulfation of peptidyl-threonine to form peptidyl-O-sulfo-L-threonine.


name: isopeptide cross-linking via N-(L-isoglutamyl)-glycine

description: The formation of an isopeptide cross-link between peptidyl-glutamate and peptidyl-glycine to produce N-(L-isoglutamyl)-glycine, as found in the antibiotic microcin J25.


description: The carboxylation of the N-terminal methionine of proteins to form the derivative N-carboxy-L-methionine.


name: N-terminal protein amino acid carboxylation

description: The carboxylation of the N-terminal amino acid of proteins.


name: N-terminal protein amino acid carbamoylation

description: The carbamoylation of the N-terminal amino acid of proteins.


name: dimethylallyl diphosphate biosynthetic process

description: The chemical reactions and pathways resulting in the formation of dimethylallyl diphosphate.


name: dimethylallyl diphosphate metabolic process

description: The chemical reactions and pathways involving dimethylallyl diphosphate.


regulation of lipid catabolic process

description: Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of lipids.


name: negative regulation of lipid catabolic process

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of lipids.


name: positive regulation of lipid catabolic process

description: Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of lipids.


quaternary ammonium group binding

description: Binding to a quaternary ammonium group, including glycine betaine, choline, carnitine and proline. A quaternary ammonium group is any compound that can be regarded as derived from ammonium hydroxide or an ammonium salt by replacement of all four hydrogen atoms of the NH4+ ion by organic groups.


nitric-oxide synthase binding

description: Binding to nitric-oxide synthase.


name: regulation of nitric-oxide synthase activity

description: Any process that modulates the activity of the enzyme nitric-oxide synthase.


name: positive regulation of nitric-oxide synthase activity

description: Any process that activates or increases the activity of the enzyme nitric-oxide synthase.


name: negative regulation of nitric-oxide synthase activity

description: Any process that stops or reduces the activity of the enzyme nitric-oxide synthase.


name: ligase activity, forming nitrogen-metal bonds

description: Catalysis of the joining of a metal ion to a molecule via a nitrogen-metal bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.


name: ligase activity, forming nitrogen-metal bonds, forming coordination complexes

description: Catalysis of the ligation of two substances via a nitrogen-metal bond, forming a coordination complex.


name: regulation of lipoprotein lipase activity

description: Any process that modulates the activity of the enzyme lipoprotein lipase.


name: negative regulation of lipoprotein lipase activity

description: Any process that stops or reduces the activity of the enzyme lipoprotein lipase.


name: positive regulation of lipoprotein lipase activity

description: Any process that activates or increases the activity of the enzyme lipoprotein lipase.


squalene-hopene cyclase activity

description: Catalysis of the reaction: squalene = hop-22(29)-ene.


Hsp27 protein binding

description: Binding to Hsp27 proteins, a lightweight heat shock protein.


description: Catalysis of the reaction: O-acetyl-L-homoserine + hydrogen sulfide = homocysteine + acetate.


microtubule plus-end binding

description: Binding to the plus end of a microtubule.


microtubule minus-end binding

description: Binding to the minus end of a microtubule.


microtubule sliding

description: The movement of one microtubule along another microtubule.


microtubule severing

description: The process in which a microtubule is broken down into smaller segments. Severing enzymes remove dimers from the middle of the filament to create new ends, unlike depolymerizing kinesins that use ATP to uncap microtubules at their ends.


actin filament severing

description: The process in which an actin filament is broken down into smaller filaments.


actin filament binding

description: Binding to an actin filament, also known as F-actin, a helical filamentous polymer of globular G-actin subunits.


barbed-end actin filament capping

description: The binding of a protein or protein complex to the barbed (or plus) end of an actin filament, thus preventing the addition, exchange or removal of further actin subunits.


actin filament bundle assembly

description: The assembly of actin filament bundles; actin filaments are on the same axis but may be oriented with the same or opposite polarities and may be packed with different levels of tightness.


protein kinase A binding

description: Binding to a protein kinase A.


name: mitogen-activated protein kinase binding

description: Binding to a mitogen-activated protein kinase.


GTPase binding

description: Binding to a GTPase, any enzyme that catalyzes the hydrolysis of GTP.


GDP-dissociation inhibitor binding

description: Binding to a GDP-dissociation inhibitor protein.


Rho GDP-dissociation inhibitor binding

description: Binding to a Rho GDP-dissociation inhibitor protein.


chiasma assembly

description: The cell cycle process in which a connection between chromatids assembles, indicating where an exchange of homologous segments has taken place by the crossing-over of non-sister chromatids.


DNA transport

description: The directed movement of RNA, deoxyribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


mRNA transport

description: The directed movement of mRNA, messenger ribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


rRNA transport

description: The directed movement of rRNA, ribosomal ribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


snRNA transport

description: The directed movement of snRNA, small nuclear ribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


tRNA transport

description: The directed movement of tRNA, transfer ribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


name: nucleic acid transmembrane transporter activity

description: Enables the transfer of nucleic acids from one side of a membrane to the other. Nucleic acids are single or double-stranded polynucleotides involved in the storage, transmission and transfer of genetic information.


RNA transmembrane transporter activity

description: Enables the transfer of RNA, ribonucleic acid, from one side of a membrane to the other.


tRNA transmembrane transporter activity

description: Enables the transfer of tRNA, transfer ribonucleic acid, from one side of a membrane to the other.


DNA transmembrane transporter activity

description: Enables the transfer of DNA, deoxyribonucleic acid, from one side of a membrane to the other.


regulation of endosome size

description: Any process that modulates the volume of an endosome, a membrane-bounded organelle that carries materials newly ingested by endocytosis.


name: regulation of calcium-independent cell-cell adhesion

description: Any process that modulates the frequency, rate or extent of the attachment of one cell to another cell via adhesion molecules that do not require the presence of calcium for the interaction.


name: positive regulation of calcium-independent cell-cell adhesion

description: Any process that activates or increases the frequency, rate or extent of calcium-independent cell-cell adhesion.


name: negative regulation of calcium-independent cell-cell adhesion

description: Any process that stops, prevents, or reduces the frequency, rate or extent of calcium-independent cell-cell adhesion.


name: regulation of membrane protein ectodomain proteolysis

description: Any process that modulates the frequency, rate or extent of the proteolytic cleavage of transmembrane proteins and release of their ectodomain (extracellular domain).


name: positive regulation of membrane protein ectodomain proteolysis

description: Any process that activates or increases the frequency, rate or extent of membrane protein ectodomain peptidolysis.


name: negative regulation of membrane protein ectodomain proteolysis

description: Any process that stops, prevents, or reduces the frequency, rate or extent of membrane protein ectodomain proteolysis.


regulation of secretion

description: Any process that modulates the frequency, rate or extent of the controlled release of a substance from a cell or a tissue.


positive regulation of secretion

description: Any process that activates or increases the frequency, rate or extent of the controlled release of a substance from a cell or a tissue.


negative regulation of secretion

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of a substance from a cell or a tissue.


regulation of transport

description: Any process that modulates the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


positive regulation of transport

description: Any process that activates or increases the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


negative regulation of transport

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


regulation of DNA metabolic process

description: Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving DNA.


name: negative regulation of DNA metabolic process

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving DNA.


name: positive regulation of DNA metabolic process

description: Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving DNA.


name: negative regulation of lipid biosynthetic process

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of lipids.


name: regulation of small GTPase mediated signal transduction

description: Any process that modulates the frequency, rate or extent of small GTPase mediated signal transduction.


name: positive regulation of small GTPase mediated signal transduction

description: Any process that activates or increases the frequency, rate or extent of small GTPase mediated signal transduction.


name: negative regulation of small GTPase mediated signal transduction

description: Any process that stops, prevents, or reduces the frequency, rate or extent of small GTPase mediated signal transduction.


NF-kappaB binding

description: Binding to NF-kappaB, a transcription factor for eukaryotic RNA polymerase II promoters.


pullulanase activity

description: Catalysis of the hydrolysis of (1,6)-alpha-D-glucosidic linkages in pullulan (a linear polymer of alpha-(1,6)-linked maltotriose units) and in amylopectin and glycogen, and the a- and b-limit dextrins of amylopectin and glycogen.


ADP reductase activity

description: Catalysis of the reaction: dADP + thioredoxin disulfide + H2O = ADP + thioredoxin.


UDP reductase activity

description: Catalysis of the reaction: dUDP + thioredoxin disulfide + H2O = UDP + thioredoxin.


CDP reductase activity

description: Catalysis of the reaction: dCDP + thioredoxin disulfide + H2O = CDP + thioredoxin.


dihydrobiopterin metabolic process

description: The chemical reactions and pathways involving a dihydrobiopterin, a reduced pteridine derivative related to folic acid; it acts as an electron carrier in tyrosine biosynthesis and its quinoid form is produced by oxidation of tetrahydrobiopterin in several biological hydroxylation reactions.


dihydropteridine metabolic process

description: The chemical reactions and pathways involving 6,7-dihydropteridine, a bicyclic compound with the formula C6H6N4.


dihydrolipoamide metabolic process

description: The chemical reactions and pathways involving dihydrolipoamide, the reduced form of lipoamide, produced as an intermediate in the reactions in which lipoamide acts as a cofactor.


galactomannan metabolic process

description: The chemical reactions and pathways involving galactomannan, a polysaccharide composed of D-galactose and D-mannose. The mannose units form the backbone structure (a linear main chain) with the D-galactose as single side units.


galactomannan biosynthetic process

description: The chemical reactions and pathways resulting in the formation of galactomannan, a polysaccharide composed of D-galactosyl and D-mannosyl. The mannosyl units form the backbone structure (a linear main chain) with the D-galactosyl as single side units.


name: 4,6-pyruvylated galactose residue metabolic process

description: The chemical reactions and pathways involving the pyruvylated galactose residue 4-6-O-[(R)(1-carboxyethylidine)]-Gal-beta-1,3-. The galactose residue is part of a larger polysaccharide chain.


name: 4,6-pyruvylated galactose residue biosynthetic process

description: The chemical reactions and pathways resulting in the formation of the pyruvylated galactose residue 4-6-O-[(R)(1-carboxyethylidine)]-Gal-beta-1,3-. The galactose residue is part of a larger polysaccharide chain.


description: Catalysis of the reaction: adenosylcobinamide-GDP + alpha-ribazole = GMP + adenosylcobalamin.


description: Catalysis of the reaction: S-adenosylmethionine + 7-(aminomethyl)-7-deazaguanosine-tRNA = adenine + methionine + epoxyqueuosine-tRNA. 7-(aminomethyl)-7-deazaguanosine-tRNA is also known as preQ1-tRNA, and epoxyqueuosine-tRNA as oQ-tRNA.


secondary cell septum

category: biolink:CellularComponent biolink:AnatomicalEntity biolink:PhysicalEssence biolink:OrganismalEntity biolink:SubjectOfInvestigation biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: Cell wall structures composed of linear polysaccharides which are deposited at both sides of the primary septum at 90 degrees to the primary septum.


meiotic nuclear membrane disassembly

description: The cell cycle process in which the controlled breakdown of the nuclear membranes during meiotic cell division occurs.


meiosis I nuclear membrane disassembly

description: The controlled breakdown of the nuclear membranes during the first division of meiosis.


meiosis II nuclear membrane disassembly

description: The controlled breakdown of the nuclear membranes during the second division of meiosis.


nuclear membrane disassembly

description: The controlled breakdown of the nuclear membranes, for example during cellular division.


unfolded protein binding

description: Binding to an unfolded protein.


name: 'de novo' cotranslational protein folding

description: The process of assisting in the correct noncovalent assembly of the ribosome-bound nascent chains of a multidomain protein whilst other parts of the protein are still being translated.


name: 'de novo' post-translational protein folding

description: The process of assisting in the correct noncovalent folding of newly formed polypeptides or folding intermediates of polypeptides that have exited the ribosome and/or have been stabilized and transferred by other chaperone proteins. This process could involve several cycles of ATP hydrolysis.


name: chaperone cofactor-dependent protein refolding

description: The process of assisting in the correct posttranslational noncovalent assembly of proteins, which is dependent on additional protein cofactors. This process occurs over one or several cycles of nucleotide hydrolysis-dependent binding and release.


name: chaperone mediated protein folding independent of cofactor

description: The process of assisting in the correct noncovalent assembly of posttranslational proteins and does not depend on additional protein cofactors. This function occurs over one or more cycles of nucleotide-dependent binding and release.


protein-folding chaperone binding

description: Binding to a chaperone protein, a class of proteins that bind to nascent or unfolded polypeptides and ensure correct folding or transport.


name: constitutive protein ectodomain proteolysis

description: The proteolytic cleavage of transmembrane proteins and release of their ectodomain that occurs constantly, regardless of environmental conditions or demands.


name: regulation of DNA-binding transcription factor activity

description: Any process that modulates the frequency, rate or extent of the activity of a transcription factor, any factor involved in the initiation or regulation of transcription.


name: positive regulation of DNA-binding transcription factor activity

description: Any process that activates or increases the frequency, rate or extent of activity of a transcription factor, any factor involved in the initiation or regulation of transcription.


name: positive regulation of NF-kappaB transcription factor activity

description: Any process that activates or increases the frequency, rate or extent of activity of the transcription factor NF-kappaB.


name: negative regulation of developmental process

description: Any process that stops, prevents or reduces the rate or extent of development, the biological process whose specific outcome is the progression of an organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).


name: positive regulation of developmental process

description: Any process that activates or increases the rate or extent of development, the biological process whose specific outcome is the progression of an organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).


regulation of helicase activity

description: Any process that modulates the frequency, rate or extent of helicase activity.


name: positive regulation of helicase activity

description: Any process that activates or increases the activity of a helicase.


name: negative regulation of helicase activity

description: Any process that stops or reduces the activity of a helicase.


regulation of binding

description: Any process that modulates the frequency, rate or extent of binding, the selective interaction of a molecule with one or more specific sites on another molecule.


positive regulation of binding

description: Any process that activates or increases the rate or extent of binding, the selective interaction of a molecule with one or more specific sites on another molecule.


negative regulation of binding

description: Any process that stops or reduces the rate or extent of binding, the selective interaction of a molecule with one or more specific sites on another molecule.


regulation of DNA binding

description: Any process that modulates the frequency, rate or extent of DNA binding. DNA binding is any process in which a gene product interacts selectively with DNA (deoxyribonucleic acid).


name: DNA ligation involved in DNA recombination

description: The re-formation of a broken phosphodiester bond in the DNA backbone, carried out by DNA ligase, that contributes to DNA recombination.


DNA ligation involved in DNA repair

description: The re-formation of a broken phosphodiester bond in the DNA backbone, carried out by DNA ligase, that contributes to DNA repair.


name: DNA-dependent DNA replication DNA ligation

description: The re-formation of a broken phosphodiester bond in the DNA backbone, carried out by DNA ligase, that contributes to DNA-dependent DNA replication.


regulation of DNA ligation

description: Any process that modulates the frequency, rate or extent of DNA ligation, the re-formation of a broken phosphodiester bond in the DNA backbone, carried out by DNA ligase.


positive regulation of DNA ligation

description: Any process that activates or increases the frequency, rate or extent of DNA ligation, the re-formation of a broken phosphodiester bond in the DNA backbone, carried out by DNA ligase.


negative regulation of DNA ligation

description: Any process that stops, prevents, or reduces the frequency, rate or extent of DNA ligation, the re-formation of a broken phosphodiester bond in the DNA backbone, carried out by DNA ligase.


carnitine-CoA ligase activity

description: Catalysis of the reaction: D-carnitine + CoA + ATP = AMP + diphosphate + D-carnitinyl-CoA.


crotonobetaine-CoA ligase activity

description: Catalysis of the reaction: CoA + crotono-betaine + ATP = AMP + diphosphate + crotonobetainyl-CoA.


name: peptidyl-histidine uridylylation, to form peptidyl-1'-(phospho-5'-uridine)-L-histidine

description: The uridylylation of peptidyl-histidine to form peptidyl-1'-(phospho-5'-uridine)-L-histidine (otherwise known as tau-UMP-histidine, tele-UMP-histidine).


peptidyl-histidine adenylylation

description: The adenylylation of peptidyl-histidine to form peptidyl-1'-(phospho-5'-adenosine)-L-histidine (otherwise known as tau-AMP-histidine, tele-AMP-histidine) or peptidyl-3'-(phospho-5'-adenosine)-L-histidine (otherwise known as pi-AMP-histidine, pros-AMP-histidine).


name: peptidyl-histidine adenylylation, to form peptidyl-1'-(phospho-5'-adenosine)-L-histidine

description: The adenylylation of peptidyl-histidine to form peptidyl-1'-(phospho-5'-adenosine)-L-histidine (otherwise known as tau-AMP-histidine, tele-AMP-histidine).


peptidyl-histidine uridylylation

description: The uridylylation of peptidyl-histidine to form peptidyl-1'-(phospho-5'-uridine)-L-histidine (otherwise known as tau-UMP-histidine, tele-UMP-histidine) or peptidyl-3'-(phospho-5'-uridine)-L-histidine (otherwise known as pi-UMP-histidine, pros-UMP-histidine).


cobaltochelatase activity

description: Catalysis of the reaction: ATP + Co(2+) + H2O + hydrogenobyrinate a,c-diamide = ADP + cob(II)yrinate a,c diamide + 4 H+ + phosphate.


ATPase binding

description: Binding to an ATPase, any enzyme that catalyzes the hydrolysis of ATP.


description: Catalysis of the endohydrolysis of (1->3)-alpha-D-glucosidic linkages in isolichenin, pseudonigeran and nigeran.


name: sugar transmembrane transporter activity

description: Enables the transfer of a sugar from one side of a membrane to the other. A sugar is any member of a class of sweet, water-soluble, crystallizable carbohydrates, which are the monosaccharides and smaller oligosaccharides.


hepoxilin A3 synthase activity

description: Catalysis of the reaction: 12S-5Z,8Z,10E,14Z-12-hydro(pero)xy-eicosa-5,8,10,14-tetraenoic acid = (5Z,9E,14Z)-(8,11R,12S)-11,12-epoxy-8-hydroxyicosa-5,9,14-trienoate. 12S-5Z,8Z,10E,14Z-12-hydro(pero)xy-eicosa-5,8,10,14-tetraenoic acid is also known as 12S-HpETE, and (5Z,9E,14Z)-(8,11R,12S)-11,12-epoxy-8-hydroxyicosa-5,9,14-trienoate as hepoxilin A3.


hepoxilin metabolic process

description: The chemical reactions and pathways involving hepoxilins, a class of bioactive icosanoids with roles in the regulation of cell physiology.


hepoxilin biosynthetic process

description: The chemical reactions and pathways resulting in the formation of hepoxilins, a class of bioactive icosanoids with roles in the regulation of cell physiology.


name: RNA polymerase II preinitiation complex assembly

description: The formation of a large multiprotein-DNA complex that self-assembles on gene promoter through the sequential recruitment of the general initiation factors that compose the preinitiation complex (PIC) (which may include TFIIA, TFIIB, TFIID, TFIIE, TFIIF, and TFIIH complexes). The PIC engages RNA polymerase II on its DNA template strand and sparks polymerization of the first few RNA nucleotides of the nascent transcript, of which 8 are base-paired with the DNA template within a DNA bubble. PIC assembly may result in a pause step, which marks the end of the PIC assembly and may be followed by promoter clearance (exact synonym: promoter escape). For RNA polymerase II PIC assembly is preceded by the formation of a nucleosome-free region that allows the transcription machinery to access the promoter DNA.


name: synaptic assembly at neuromuscular junction

description: The assembly of a synapse at a neuromuscular junction.


regulation of actin nucleation

description: Any process that modulates the frequency, rate or extent of actin nucleation, the initial step in the formation of an actin filament in which actin monomers combine to form a new filament.


negative regulation of actin nucleation

description: Any process that stops, prevents, or reduces the frequency, rate or extent of actin nucleation, the initial step in the formation of an actin filament in which actin monomers combine to form a new filament.


positive regulation of actin nucleation

description: Any process that activates or increases the frequency, rate or extent of actin nucleation, the initial step in the formation of an actin filament in which actin monomers combine to form a new filament.


name: regulation of cellular component organization

description: Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.


name: negative regulation of cellular component organization

description: Any process that stops, prevents, or reduces the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.


name: positive regulation of cellular component organization

description: Any process that activates or increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.


name: chaperone-mediated protein complex assembly

description: The aggregation, arrangement and bonding together of a set of components to form a protein complex, mediated by chaperone molecules that do not form part of the finished complex.


NK T cell activation

description: The change in morphology and behavior of a mature or immature natural killer T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.


regulation of NK T cell activation

description: Any process that modulates the frequency, rate or extent of natural killer T cell activation.


name: negative regulation of NK T cell activation

description: Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer T cell activation.


name: positive regulation of NK T cell activation

description: Any process that activates or increases the frequency, rate or extent of natural killer T cell activation.


regulation of NK T cell differentiation

description: Any process that modulates the frequency, rate or extent of natural killer T cell differentiation.


name: negative regulation of NK T cell differentiation

description: Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer T cell differentiation.


name: positive regulation of NK T cell differentiation

description: Any process that activates or increases the frequency, rate or extent of natural killer T cell differentiation.


metal cation:proton antiporter activity

description: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: metal ion(in) + H+(out) = metal ion(out) + H+(in).


regulation of NK T cell proliferation

description: Any process that modulates the frequency, rate or extent of natural killer T cell proliferation.


name: negative regulation of NK T cell proliferation

description: Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer T cell proliferation.


name: positive regulation of NK T cell proliferation

description: Any process that activates or increases the frequency, rate or extent of natural killer T cell proliferation.


propanediol metabolic process

description: The chemical reactions and pathways involving propanediol, CH3-CHOH-CH2OH, a sweet, colorless, viscous, hygroscopic liquid used as an antifreeze, in brake fluid and as a humectant in cosmetics and personal care items.


propanediol catabolic process

description: The chemical reactions and pathways resulting in the breakdown of propanediol, a sweet, colorless, viscous, hygroscopic liquid with the formula CH3-CHOH-CH2OH.


smooth muscle cell differentiation

description: The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell; smooth muscle lacks transverse striations in its constituent fibers and are almost always involuntary.


striated muscle cell differentiation

description: The process in which a relatively unspecialized cell acquires specialized features of a striated muscle cell; striated muscle fibers are divided by transverse bands into striations, and cardiac and voluntary muscle are types of striated muscle.


name: regulation of muscle cell differentiation

description: Any process that modulates the frequency, rate or extent of muscle cell differentiation.


name: negative regulation of muscle cell differentiation

description: Any process that stops, prevents, or reduces the frequency, rate or extent of muscle cell differentiation.


name: positive regulation of muscle cell differentiation

description: Any process that activates or increases the frequency, rate or extent of muscle cell differentiation.


name: regulation of smooth muscle cell differentiation

description: Any process that modulates the frequency, rate or extent of smooth muscle cell differentiation.


name: negative regulation of smooth muscle cell differentiation

description: Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle cell differentiation.


name: positive regulation of smooth muscle cell differentiation

description: Any process that activates or increases the frequency, rate or extent of smooth muscle cell differentiation.


name: regulation of striated muscle cell differentiation

description: Any process that modulates the frequency, rate or extent of striated muscle cell differentiation.


name: negative regulation of striated muscle cell differentiation

description: Any process that stops, prevents, or reduces the frequency, rate or extent of striated muscle cell differentiation.


name: positive regulation of striated muscle cell differentiation

description: Any process that activates or increases the frequency, rate or extent of striated muscle cell differentiation.


glucose 6-phosphate metabolic process

description: The chemical reactions and pathways involving glucose 6-phosphate, a monophosphorylated derivative of glucose with the phosphate group attached to C-6.


arabitol catabolic process

description: The chemical reactions and pathways resulting in the breakdown of arabitol, the pentitol derived from arabinose or lyxose by reduction of the aldehyde group.


L-arabitol catabolic process

description: The chemical reactions and pathways resulting in the breakdown of L-arabitol, the pentitol derived from arabinose or lyxose by reduction of the aldehyde group.


D-arabitol catabolic process

description: The chemical reactions and pathways resulting in the breakdown of D-arabitol, the pentitol derived from arabinose or lyxose by reduction of the aldehyde group. The D enantiomer is present in lichens and mushrooms.


L-xylitol catabolic process

description: The chemical reactions and pathways resulting in the breakdown of L-xylitol, a five-carbon sugar alcohol derived from xylose by reduction of the carbonyl group.


arabitol metabolic process

description: The chemical reactions and pathways involving arabitol, the pentitol derived from arabinose or lyxose by reduction of the aldehyde group.


L-arabitol metabolic process

description: The chemical reactions and pathways involving L-arabitol, the pentitol derived from arabinose or lyxose by reduction of the aldehyde group.


D-arabitol metabolic process

description: The chemical reactions and pathways involving D-arabitol, the pentitol derived from arabinose or lyxose by reduction of the aldehyde group. The D enantiomer is present in lichens and mushrooms.


L-xylitol metabolic process

description: The chemical reactions and pathways involving L-xylitol, a five-carbon sugar alcohol derived from xylose by reduction of the carbonyl group. It is as sweet as sucrose and is used as a noncariogenic sweetner and as a sugar substitute in diabetic diets.


2,5-dihydroxypyridine metabolic process

description: The chemical reactions and pathways involving 2,5-dihydroxypyridine.


2,5-dihydroxypyridine catabolic process

description: The chemical reactions and pathways resulting in the breakdown of 2,5-dihydroxypyridine.


xylulose 5-phosphate metabolic process

description: The chemical reactions and pathways involving xylulose 5-phosphate, a derivative of the ketopentose xylulose phosphorylated at the 5 carbon; it is an intermediate in the pentose phosphate pathway.


nuclear export

description: The directed movement of substances out of the nucleus.


nuclear transport

description: The directed movement of substances into, out of, or within the nucleus.


import into nucleus

description: The directed movement of substances into the nucleus.


name: regulation of phosphorus metabolic process

description: Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus.


name: negative regulation of sulfur metabolic process

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving sulfur or compounds containing sulfur.


name: positive regulation of sulfur metabolic process

description: Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving sulfur or compounds containing sulfur.


meiotic sister chromatid cohesion

description: The cell cycle process in which sister chromatids of a replicated chromosome are joined along the entire length of the chromosome during meiosis.


localization

description: Any process in which a cell, a substance, or a cellular entity, such as a protein complex or organelle, is transported, tethered to or otherwise maintained in a specific location. In the case of substances, localization may also be achieved via selective degradation.


vitamin transport

description: The directed movement of vitamins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A vitamin is one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body.


prosthetic group metabolic process

description: The chemical reactions and pathways involving a prosthetic group, the non-amino acid portion of certain protein molecules. Prosthetic groups may be inorganic or organic and are usually required for the biological activity of the protein.


prosthetic group catabolic process

description: The chemical reactions and pathways resulting in the breakdown of a prosthetic group, the non-amino acid portion of certain protein molecules. Prosthetic groups may be inorganic or organic and are usually required for the biological activity of the protein.


prosthetic group biosynthetic process

description: The chemical reactions and pathways resulting in the formation of a prosthetic group, the non-amino acid portion of certain protein molecules. Prosthetic groups may be inorganic or organic and are usually required for the biological activity of the protein.


prosthetic group binding

description: Binding to a prosthetic group, the non-amino acid portion of certain protein molecules. Prosthetic groups may be inorganic or organic and are usually required for the biological activity of the protein.


phytochromobilin metabolic process

description: The chemical reactions and pathways involving phytochromobilin, the linear tetrapyrrole chromophore required for plant phytochrome photoactivity.


name: peptidyl-aspartic acid reduction to form L-aspartyl aldehyde

description: The reduction of peptidyl-aspartic acid to form peptidyl-L-aspartyl aldehyde, as found photosystem II P680 chlorophyll A apoprotein.


name: protein insertion into mitochondrial membrane

description: The process that results in the incorporation of a protein into a mitochondrial membrane.


protein insertion into membrane

description: The process that results in the incorporation of a protein into a biological membrane. Incorporation in this context means having some part or covalently attached group that is inserted into the the hydrophobic region of one or both bilayers.


silicate metabolic process

description: The chemical reactions and pathways involving silicates, the salts of silicic acids. Silicates are usually composed of silicon and oxygen (Si[x]O[y]), one or more metals, and possibly hydrogen. Types of silicate include unisilicates, metasilicates and hydrous silicates.


sequestering of calcium ion

description: The process of binding or confining calcium ions such that they are separated from other components of a biological system.


name: release of sequestered calcium ion into cytosol

description: The process in which calcium ions sequestered in the endoplasmic reticulum, Golgi apparatus or mitochondria are released into the cytosolic compartment.


isotropic cell growth

description: The process in which a cell irreversibly increases in size uniformly in all directions. In general, a rounded cell morphology reflects isotropic cell growth.


anisotropic cell growth

description: The process in which a cell irreversibly increases in size in one or more axes, where the growth rate varies according to the direction of growth. Growth may be limited to a particular axis, axes, or to particular locations on the surface of the cell.


vanadium ion binding

description: Binding to a vanadium ion (V).


dioxygenase activity

description: Catalysis of an oxidation-reduction (redox) reaction in which both atoms of oxygen from one molecule of O2 are incorporated into the (reduced) product(s) of the reaction. The two atoms of oxygen may be distributed between two different products.


name: RNAi-mediated antiviral immunity against RNA virus

description: An RNAi-mediated post-transcriptional gene silencing pathway induced by RNA viruses leading to a sequence-specific degradation of target mRNAs or inhibition of translation. In plants, DCL4 is the primary Dicer to detect RNA viruses.


name: RNAi-mediated antiviral immunity against DNA virus

description: An RNAi-mediated post-transcriptional gene silencing pathway induced by DNA viruses leading to a sequence-specific degradation of target mRNAs or inhibition of translation. In plants, DCL3 is the primary Dicer to detect DNA viruses.


cartilage development

description: The process whose specific outcome is the progression of a cartilage element over time, from its formation to the mature structure. Cartilage elements are skeletal elements that consist of connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate.


name: molybdenum incorporation via L-aspartyl molybdenum bis(molybdopterin guanine dinucleotide)

description: The incorporation of molybdenum into a protein via L-aspartyl molybdenum bis(molybdopterin guanine dinucleotide).


name: tungsten incorporation via L-selenocysteinyl tungsten bis(molybdopterin guanine dinucleotide)

description: The incorporation of tungsten into a protein via L-selenocysteinyl tungsten bis(molybdopterin guanine dinucleotide).


phosphoprotein binding

description: Binding to a phosphorylated protein.


cytoplasmic sequestering of protein

description: The selective interaction of a protein with specific molecules in the cytoplasm, thereby inhibiting its transport into other areas of the cell.


name: tungsten incorporation into metallo-sulfur cluster

description: The incorporation of tungsten into a metallo-sulfur cluster.


name: positive regulation of protein transport

description: Any process that activates or increases the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


regulation of protein transport

description: Any process that modulates the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


name: negative regulation of protein transport

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


spindle assembly

description: The aggregation, arrangement and bonding together of a set of components to form the spindle, the array of microtubules and associated molecules that serves to move duplicated chromosomes apart.


mitotic spindle disassembly

description: The controlled breakdown of the spindle during a mitotic cell cycle.


meiotic spindle disassembly

description: The controlled breakdown of the spindle during a meiotic cell cycle.


spindle disassembly

description: The controlled breakdown of the spindle, the array of microtubules and associated molecules that serves to move duplicated chromosomes apart.


spindle elongation

description: The cell cycle process in which the distance is lengthened between poles of the spindle.


meiotic spindle elongation

description: The lengthening of the distance between poles of the spindle during a meiotic cell cycle.


spindle midzone

description: The area in the center of the spindle where the spindle microtubules from opposite poles overlap.


establishment of localization

description: Any process that localizes a substance or cellular component. This may occur via movement, tethering or selective degradation.


maintenance of location

description: Any process in which a cell, substance or cellular entity, such as a protein complex or organelle, is maintained in a location and prevented from moving elsewhere.


establishment of RNA localization

description: The directed movement of RNA to a specific location.


maintenance of RNA location

description: Any process in which RNA is maintained in a location and prevented from moving elsewhere.


sequestering of metal ion

description: The process of binding or confining metal ions such that they are separated from other components of a biological system.


name: regulation of multicellular organismal process

description: Any process that modulates the frequency, rate or extent of a multicellular organismal process, the processes pertinent to the function of a multicellular organism above the cellular level; includes the integrated processes of tissues and organs.


name: positive regulation of multicellular organismal process

description: Any process that activates or increases the frequency, rate or extent of an organismal process, any of the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs.


name: negative regulation of multicellular organismal process

description: Any process that stops, prevents, or reduces the frequency, rate or extent of an organismal process, the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs.


name: negative regulation of cellular defense response

description: Any process that stops, prevents, or reduces the rate of the cellular defense response.


regulation of protein metabolic process

description: Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a protein.


name: positive regulation of protein metabolic process

description: Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a protein.


name: negative regulation of protein metabolic process

description: Any process that stops, prevents, or reduces the frequency, rate or extent of chemical reactions and pathways involving a protein.


regulation of lymphocyte activation

description: Any process that modulates the frequency, rate or extent of lymphocyte activation.


name: negative regulation of lymphocyte activation

description: Any process that stops, prevents, or reduces the frequency, rate or extent of lymphocyte activation.


name: positive regulation of lymphocyte activation

description: Any process that activates or increases the frequency, rate or extent of lymphocyte activation.


regulation of RNA metabolic process

description: Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving RNA.


name: negative regulation of RNA metabolic process

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving RNA.


name: positive regulation of RNA metabolic process

description: Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving RNA.


spindle midzone assembly

description: The cell cycle process in which aggregation, arrangement and bonding together of a set of components to form the spindle midzone. The spindle midzone is the area in the center of the spindle where the spindle microtubules from opposite poles overlap.


mitotic spindle midzone assembly

description: The cell cycle process in which the aggregation, arrangement and bonding together of a set of components forms the spindle midzone.


meiotic spindle midzone assembly

description: The formation of the spindle midzone, the area in the center of the spindle where the spindle microtubules from opposite poles overlap, as a part of the process of meiosis.


protein polymerization

description: The process of creating protein polymers, compounds composed of a large number of component monomers; polymeric proteins may be made up of different or identical monomers. Polymerization occurs by the addition of extra monomers to an existing poly- or oligomeric protein.


protein complex oligomerization

description: The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of component monomers; protein oligomers may be composed of different or identical monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.


protein homooligomerization

description: The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of identical component monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.


protein depolymerization

description: The process in which protein polymers, compounds composed of a large number of component monomers, are broken down. Depolymerization occurs by the successive removal of monomers from an existing poly- or oligomeric protein.


protein tetramerization

description: The formation of a protein tetramer, a macromolecular structure consisting of four noncovalently associated identical or nonidentical subunits.


mono-olein transacylation activity

description: Catalysis of the reaction: mono-olein + mono-olein = diolein + glycerol. Mono-olein, also known as mono-oleoylglycerol, is the monoglyceride formed from oleic acid, 9-octodecenoic acid; diolein is also known as dioleoylglycerol.


diolein transacylation activity

description: Catalysis of the reaction: diolein + mono-olein = triolein + glycerol. Mono-olein, also known as mono-oleoylglycerol, is the monoglyceride formed from oleic acid, 9-octodecenoic acid; diolein is also known as dioleoylglycerol, and triolein as trioleoylglycerol and olein.


description: Catalysis of the reaction: siroheme + 2 H+ = Fe(2+) + sirohydrochlorin.


name: CP2 mannose-ethanolamine phosphotransferase activity

description: Catalysis of the reaction: ethanolamine phosphate + Man-alpha-(1,2)-Man-alpha-(1,2)-Man-alpha-(1,6)-R = Man-alpha-(1,2)-Man-alpha-6-P-EtN-(1,2)-Man-alpha-(1,6)-R; R is Man-alpha(1,4)-GlcNH2-inositol-phosphate-lipid. This reaction is the transfer of ethanolamine phosphate to C6 of second mannose in the GPI lipid precursor CP2.