name: somatic diversification of T cell receptor genes

description: The somatic process that results in the generation of sequence diversity of T cell receptor genes.


name: somatic diversification of immune receptors by N region addition

category: biolink:BiologicalProcess biolink:Occurrent biolink:OntologyClass biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: The addition of variable numbers of random nucleotides by terminal deoxytransferase in the N regions of heavy chain immunoglobulin and T cell receptor genes. N regions are found at the V-D, D-D, V-J, and D-J recombinational junctions, depending on the immune receptor gene.


name: somatic diversification of immunoglobulin genes by N region addition

description: The addition of variable numbers of random nucleotides by terminal deoxytransferase in the N regions of heavy chain immunoglobulin genes. N regions are found at the V-D and D-J recombinational junctions.


name: somatic diversification of T cell receptor genes by N region addition

description: The addition of variable numbers of random nucleotides by terminal deoxytransferase in the N regions of T cell receptor genes. N regions are found at the V-D, D-D, V-J, and D-J recombinational junctions, depending on the T cell receptor gene.


pro-T cell differentiation

description: The process in which a precursor cell type acquires the specialized features of a pro-T cell. Pro-T cells are the earliest stage of the T cell lineage but are not fully committed.


myeloid leukocyte differentiation

description: The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of any cell of the myeloid leukocyte lineage.


thrombocyte differentiation

description: The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a thrombocyte, a nucleated cell found in all vertebrates but mammals involved in hemostasis.


basophil chemotaxis

description: The movement of a basophil in response to an external stimulus.


platelet degranulation

description: The regulated exocytosis of secretory granules containing preformed mediators such as histamine and serotonin by a platelet.


name: regulation of antigen processing and presentation

description: Any process that modulates the frequency, rate, or extent of antigen processing and presentation.


name: negative regulation of antigen processing and presentation

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation.


name: positive regulation of antigen processing and presentation

description: Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation.


name: regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II

description: Any process that modulates the frequency, rate, or extent of antigen processing and presentation of antigen (peptide or polysaccharide) via MHC class II.


name: negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of antigen (peptide or polysaccharide) via MHC class II.


name: positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II

description: Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of antigen (peptide or polysaccharide) via MHC class II.


name: regulation of antigen processing and presentation of peptide antigen

description: Any process that modulates the frequency, rate, or extent of antigen processing and presentation of peptide antigen.


name: negative regulation of antigen processing and presentation of peptide antigen

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of peptide antigen.


name: positive regulation of antigen processing and presentation of peptide antigen

description: Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of peptide antigen.


name: regulation of antigen processing and presentation of peptide antigen via MHC class II

description: Any process that modulates the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class II.


name: negative regulation of antigen processing and presentation of peptide antigen via MHC class II

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class II.


name: positive regulation of antigen processing and presentation of peptide antigen via MHC class II

description: Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class II.


name: regulation of antigen processing and presentation of peptide antigen via MHC class I

description: Any process that modulates the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class I.


name: negative regulation of antigen processing and presentation of peptide antigen via MHC class I

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class I.


name: positive regulation of antigen processing and presentation of peptide antigen via MHC class I

description: Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class I.


name: regulation of antigen processing and presentation via MHC class Ib

description: Any process that modulates the frequency, rate, or extent of antigen processing and presentation of antigen via MHC class Ib.


name: negative regulation of antigen processing and presentation via MHC class Ib

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of antigen via MHC class Ib.


name: positive regulation of antigen processing and presentation via MHC class Ib

description: Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of antigen via MHC class Ib.


name: regulation of antigen processing and presentation of peptide antigen via MHC class Ib

description: Any process that modulates the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class Ib.


name: negative regulation of antigen processing and presentation of peptide antigen via MHC class Ib

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class Ib.


name: positive regulation of antigen processing and presentation of peptide antigen via MHC class Ib

description: Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class Ib.


name: regulation of antigen processing and presentation of lipid antigen via MHC class Ib

description: Any process that modulates the frequency, rate, or extent of antigen processing and presentation of lipid antigen via MHC class Ib.


name: negative regulation of antigen processing and presentation of lipid antigen via MHC class Ib

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of lipid antigen via MHC class Ib.


name: positive regulation of antigen processing and presentation of lipid antigen via MHC class Ib

description: Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of lipid antigen via MHC class Ib.


name: regulation of antigen processing and presentation of polysaccharide antigen via MHC class II

description: Any process that modulates the frequency, rate, or extent of antigen processing and presentation of polysaccharide antigen via MHC class II.


name: negative regulation of antigen processing and presentation of polysaccharide antigen via MHC class II

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of polysaccharide antigen via MHC class II.


name: positive regulation of antigen processing and presentation of polysaccharide antigen via MHC class II

description: Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of polysaccharide antigen via MHC class II.


name: regulation of dendritic cell antigen processing and presentation

description: Any process that modulates the frequency, rate, or extent of dendritic cell antigen processing and presentation.


name: negative regulation of dendritic cell antigen processing and presentation

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of dendritic cell antigen processing and presentation.


name: positive regulation of dendritic cell antigen processing and presentation

description: Any process that activates or increases the frequency, rate, or extent of dendritic cell antigen processing and presentation.


name: regulation of myeloid dendritic cell antigen processing and presentation

description: Any process that modulates the frequency, rate, or extent of myeloid dendritic cell antigen processing and presentation.


name: negative regulation of myeloid dendritic cell antigen processing and presentation

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid dendritic cell antigen processing and presentation.


name: positive regulation of myeloid dendritic cell antigen processing and presentation

description: Any process that activates or increases the frequency, rate, or extent of myeloid dendritic cell antigen processing and presentation.


name: regulation of plasmacytoid dendritic cell antigen processing and presentation

description: Any process that modulates the frequency, rate, or extent of plasmacytoid dendritic cell antigen processing and presentation.


name: negative regulation of plasmacytoid dendritic cell antigen processing and presentation

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of plasmacytoid dendritic cell antigen processing and presentation.


name: positive regulation of plasmacytoid dendritic cell antigen processing and presentation

description: Any process that activates or increases the frequency, rate, or extent of plasmacytoid dendritic cell antigen processing and presentation.


name: regulation of monocyte antigen processing and presentation

description: Any process that modulates the frequency, rate, or extent of monocyte antigen processing and presentation.


name: negative regulation of monocyte antigen processing and presentation

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of monocyte antigen processing and presentation.


name: positive regulation of monocyte antigen processing and presentation

description: Any process that activates or increases the frequency, rate, or extent of monocyte antigen processing and presentation.


name: regulation of macrophage antigen processing and presentation

description: Any process that modulates the frequency, rate, or extent of macrophage antigen processing and presentation.


name: negative regulation of macrophage antigen processing and presentation

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of macrophage antigen processing and presentation.


name: positive regulation of macrophage antigen processing and presentation

description: Any process that activates or increases the frequency, rate, or extent of macrophage antigen processing and presentation.


name: regulation of non-professional antigen presenting cell antigen processing and presentation

description: Any process that modulates the frequency, rate, or extent of non-professional antigen presenting cell antigen processing and presentation.


name: negative regulation of non-professional antigen presenting cell antigen processing and presentation

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of non-professional antigen presenting cell antigen processing and presentation.


name: positive regulation of non-professional antigen presenting cell antigen processing and presentation

description: Any process that activates or increases the frequency, rate, or extent of non-professional antigen presenting cell antigen processing and presentation.


name: regulation of B cell antigen processing and presentation

description: Any process that modulates the frequency, rate, or extent of B cell antigen processing and presentation.


name: negative regulation of B cell antigen processing and presentation

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell antigen processing and presentation.


name: positive regulation of B cell antigen processing and presentation

description: Any process that activates or increases the frequency, rate, or extent of B cell antigen processing and presentation.


name: regulation of T cell antigen processing and presentation

description: Any process that modulates the frequency, rate, or extent of T cell antigen processing and presentation.


name: negative regulation of T cell antigen processing and presentation

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell antigen processing and presentation.


name: positive regulation of T cell antigen processing and presentation

description: Any process that activates or increases the frequency, rate, or extent of T cell antigen processing and presentation.


name: regulation of proteolysis associated with antigen processing and presentation

description: Any process that modulates the frequency, rate, or extent of proteolysis associated with antigen processing and presentation.


name: negative regulation of proteolysis associated with antigen processing and presentation

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of proteolysis associated with antigen processing and presentation.


name: positive regulation of proteolysis associated with antigen processing and presentation

description: Any process that activates or increases the frequency, rate, or extent of proteolysis associated with antigen processing and presentation.


regulation of granuloma formation

description: Any process that modulates the frequency, rate, or extent of granuloma formation.


name: negative regulation of granuloma formation

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of granuloma formation.


name: positive regulation of granuloma formation

description: Any process that activates or increases the frequency, rate, or extent of granuloma formation.


regulation of germinal center formation

description: Any process that modulates the frequency, rate, or extent of germinal center formation.


name: negative regulation of germinal center formation

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of germinal center formation.


name: positive regulation of germinal center formation

description: Any process that activates or increases the frequency, rate, or extent of germinal center formation.


regulation of immunoglobulin production

description: Any process that modulates the frequency, rate, or extent of immunoglobulin production.


name: negative regulation of immunoglobulin production

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of immunoglobulin production.


name: positive regulation of immunoglobulin production

description: Any process that activates or increases the frequency, rate, or extent of immunoglobulin production.


regulation of tolerance induction

description: Any process that modulates the frequency, rate, or extent of tolerance induction.


name: negative regulation of tolerance induction

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of tolerance induction.


name: positive regulation of tolerance induction

description: Any process that activates or increases the frequency, rate, or extent of tolerance induction.


name: regulation of central tolerance induction

description: Any process that modulates the frequency, rate, or extent of central tolerance induction.


name: negative regulation of central tolerance induction

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of central tolerance induction.


name: positive regulation of central tolerance induction

description: Any process that activates or increases the frequency, rate, or extent of central tolerance induction.


name: regulation of tolerance induction to self antigen

description: Any process that modulates the frequency, rate, or extent of tolerance induction to self antigen.


name: negative regulation of tolerance induction to self antigen

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of tolerance induction to self antigen.


name: positive regulation of tolerance induction to self antigen

description: Any process that activates or increases the frequency, rate, or extent of tolerance induction to self antigen.


name: regulation of tolerance induction dependent upon immune response

description: Any process that modulates the frequency, rate, or extent of tolerance induction dependent upon immune response.


name: negative regulation of tolerance induction dependent upon immune response

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of tolerance induction dependent upon immune response.


name: positive regulation of tolerance induction dependent upon immune response

description: Any process that activates or increases the frequency, rate, or extent of tolerance induction dependent upon immune response.


name: regulation of tolerance induction to nonself antigen

description: Any process that modulates the frequency, rate, or extent of tolerance induction to nonself antigen.


name: negative regulation of tolerance induction to nonself antigen

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of tolerance induction to nonself antigen.


name: positive regulation of tolerance induction to nonself antigen

description: Any process that activates or increases the frequency, rate, or extent of tolerance induction to nonself antigen.


name: regulation of peripheral tolerance induction

description: Any process that modulates the frequency, rate, or extent of peripheral tolerance induction.


name: negative regulation of peripheral tolerance induction

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of peripheral tolerance induction.


name: positive regulation of peripheral tolerance induction

description: Any process that activates or increases the frequency, rate, or extent of peripheral tolerance induction.


name: regulation of B cell tolerance induction

description: Any process that modulates the frequency, rate, or extent of B cell tolerance induction.


name: negative regulation of B cell tolerance induction

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell tolerance induction.


name: positive regulation of B cell tolerance induction

description: Any process that activates or increases the frequency, rate, or extent of B cell tolerance induction.


name: regulation of T cell tolerance induction

description: Any process that modulates the frequency, rate, or extent of T cell tolerance induction.


name: negative regulation of T cell tolerance induction

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell tolerance induction.


name: positive regulation of T cell tolerance induction

description: Any process that activates or increases the frequency, rate, or extent of T cell tolerance induction.


regulation of T cell anergy

description: Any process that modulates the frequency, rate, or extent of T cell anergy.


negative regulation of T cell anergy

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell anergy.


positive regulation of T cell anergy

description: Any process that activates or increases the frequency, rate, or extent of T cell anergy.


regulation of B cell anergy

description: Any process that modulates the frequency, rate, or extent of B cell anergy.


negative regulation of B cell anergy

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell anergy.


positive regulation of B cell anergy

description: Any process that activates or increases the frequency, rate, or extent of B cell anergy.


name: regulation of acute inflammatory response

description: Any process that modulates the frequency, rate, or extent of an acute inflammatory response.


name: negative regulation of acute inflammatory response

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of an acute inflammatory response.


name: positive regulation of acute inflammatory response

description: Any process that activates or increases the frequency, rate, or extent of an acute inflammatory response.


name: regulation of chronic inflammatory response

description: Any process that modulates the frequency, rate, or extent of a chronic inflammatory response.


name: negative regulation of chronic inflammatory response

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of a chronic inflammatory response.


name: positive regulation of chronic inflammatory response

description: Any process that activates or increases the frequency, rate, or extent of a chronic inflammatory response.


name: respiratory burst involved in defense response

description: A phase of elevated metabolic activity, during which oxygen consumption increases made as part of a defense response ; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals.


pro-T cell lineage commitment

description: The process in which a lymphoid progenitor cell becomes committed to becoming a pro-T cell.


name: somatic recombination of T cell receptor gene segments

description: The process in which T cell receptor genes are formed through recombination of the germline genetic elements, also known as T cell receptor gene segments.


regulation of immune system process

description: Any process that modulates the frequency, rate, or extent of an immune system process.


name: negative regulation of immune system process

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of an immune system process.


name: positive regulation of immune system process

description: Any process that activates or increases the frequency, rate, or extent of an immune system process.


regulation of leukocyte migration

description: Any process that modulates the frequency, rate, or extent of leukocyte migration.


name: negative regulation of leukocyte migration

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte migration.


name: positive regulation of leukocyte migration

description: Any process that activates or increases the frequency, rate, or extent of leukocyte migration.


regulation of leukocyte chemotaxis

description: Any process that modulates the frequency, rate, or extent of leukocyte chemotaxis.


name: negative regulation of leukocyte chemotaxis

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte chemotaxis.


name: positive regulation of leukocyte chemotaxis

description: Any process that activates or increases the frequency, rate, or extent of leukocyte chemotaxis.


regulation of cellular extravasation

description: Any process that modulates the frequency, rate, or extent of cellular extravasation.


name: negative regulation of cellular extravasation

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of cellular extravasation.


name: positive regulation of cellular extravasation

description: Any process that activates or increases the frequency, rate, or extent of cellular extravasation.


regulation of leukocyte activation

description: Any process that modulates the frequency, rate, or extent of leukocyte activation.


name: negative regulation of leukocyte activation

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte activation.


name: positive regulation of leukocyte activation

description: Any process that activates or increases the frequency, rate, or extent of leukocyte activation.


regulation of immune effector process

description: Any process that modulates the frequency, rate, or extent of an immune effector process.


name: negative regulation of immune effector process

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of an immune effector process.


name: positive regulation of immune effector process

description: Any process that activates or increases the frequency, rate, or extent of an immune effector process.


name: regulation of production of molecular mediator of immune response

description: Any process that modulates the frequency, rate, or extent of the production of molecular mediator of immune response.


name: negative regulation of production of molecular mediator of immune response

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of the production of molecular mediator of immune response.


name: positive regulation of production of molecular mediator of immune response

description: Any process that activates or increases the frequency, rate, or extent of the production of molecular mediator of immune response.


name: regulation of leukocyte mediated immunity

description: Any process that modulates the frequency, rate, or extent of leukocyte mediated immunity.


name: negative regulation of leukocyte mediated immunity

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte mediated immunity.


name: positive regulation of leukocyte mediated immunity

description: Any process that activates or increases the frequency, rate, or extent of leukocyte mediated immunity.


name: regulation of lymphocyte mediated immunity

description: Any process that modulates the frequency, rate, or extent of lymphocyte mediated immunity.


name: negative regulation of lymphocyte mediated immunity

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of lymphocyte mediated immunity.


name: positive regulation of lymphocyte mediated immunity

description: Any process that activates or increases the frequency, rate, or extent of lymphocyte mediated immunity.


regulation of T cell mediated immunity

description: Any process that modulates the frequency, rate, or extent of T cell mediated immunity.


name: negative regulation of T cell mediated immunity

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell mediated immunity.


name: positive regulation of T cell mediated immunity

description: Any process that activates or increases the frequency, rate, or extent of T cell mediated immunity.


regulation of B cell mediated immunity

description: Any process that modulates the frequency, rate, or extent of B cell mediated immunity.


name: negative regulation of B cell mediated immunity

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell mediated immunity.


name: positive regulation of B cell mediated immunity

description: Any process that activates or increases the frequency, rate, or extent of B cell mediated immunity.


name: regulation of natural killer cell mediated immunity

description: Any process that modulates the frequency, rate, or extent of natural killer cell mediated immunity.


name: negative regulation of natural killer cell mediated immunity

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of natural killer cell mediated immunity.


name: positive regulation of natural killer cell mediated immunity

description: Any process that activates or increases the frequency, rate, or extent of natural killer cell mediated immunity.


name: regulation of cytokine production involved in immune response

description: Any process that modulates the frequency, rate, or extent of cytokine production that contributes to an immune response.


name: negative regulation of cytokine production involved in immune response

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of cytokine production contributing to an immune response.


name: positive regulation of cytokine production involved in immune response

description: Any process that activates or increases the frequency, rate, or extent of cytokine production that contributes to an immune response.


name: regulation of B cell cytokine production

description: Any process that modulates the frequency, rate, or extent of B cell cytokine production.


name: negative regulation of B cell cytokine production

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell cytokine production.


name: positive regulation of B cell cytokine production

description: Any process that activates or increases the frequency, rate, or extent of B cell cytokine production.


name: regulation of T cell cytokine production

description: Any process that modulates the frequency, rate, or extent of T cell cytokine production.


name: negative regulation of T cell cytokine production

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell cytokine production.


name: positive regulation of T cell cytokine production

description: Any process that activates or increases the frequency, rate, or extent of T cell cytokine production.


name: regulation of natural killer cell cytokine production

description: Any process that modulates the frequency, rate, or extent of natural killer cell cytokine production.


name: negative regulation of natural killer cell cytokine production

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of natural killer cell cytokine production.


name: positive regulation of natural killer cell cytokine production

description: Any process that activates or increases the frequency, rate, or extent of natural killer cell cytokine production.


name: regulation of dendritic cell cytokine production

description: Any process that modulates the frequency, rate, or extent of dendritic cell cytokine production.


name: negative regulation of dendritic cell cytokine production

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of dendritic cell cytokine production.


name: positive regulation of dendritic cell cytokine production

description: Any process that activates or increases the frequency, rate, or extent of dendritic cell cytokine production.


name: regulation of myeloid dendritic cell cytokine production

description: Any process that modulates the frequency, rate, or extent of myeloid dendritic cell cytokine production.


name: negative regulation of myeloid dendritic cell cytokine production

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid dendritic cell cytokine production.


name: positive regulation of myeloid dendritic cell cytokine production

description: Any process that activates or increases the frequency, rate, or extent of myeloid dendritic cell cytokine production.


name: regulation of plasmacytoid dendritic cell cytokine production

description: Any process that modulates the frequency, rate, or extent of plasmacytoid dendritic cell cytokine production.


name: negative regulation of plasmacytoid dendritic cell cytokine production

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of plasmacytoid dendritic cell cytokine production.


name: positive regulation of plasmacytoid dendritic cell cytokine production

description: Any process that activates or increases the frequency, rate, or extent of plasmacytoid dendritic cell cytokine production.


name: antigen processing and presentation initiated by receptor mediated uptake of antigen

description: Antigen processing and presentation which is initiated by uptake of antigen bound to a cell surface receptor.


name: antigen processing and presentation following pinocytosis

description: Antigen processing and presentation which is initiated by uptake of antigen via pinocytosis.


name: antigen processing and presentation following phagocytosis

description: Antigen processing and presentation which is initiated by uptake of antigen via phagocytosis.


name: antigen processing and presentation initiated by pattern recognition receptor mediated uptake of antigen

description: Antigen processing and presentation which is initiated by uptake of antigen bound to a cell surface pattern recognition receptor (PRR).


name: antigen processing and presentation following macropinocytosis

description: Antigen processing and presentation which is initiated by uptake of antigen via macropinocytosis.


name: antigen processing and presentation following receptor mediated endocytosis

description: Antigen processing and presentation which is initiated by uptake of antigen receptor-mediated endocytosis.


name: cell surface pattern recognition receptor signaling pathway

category: biolink:Pathway biolink:OntologyClass biolink:BiologicalProcess biolink:Occurrent biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: The series of molecular signals initiated by a ligand binding to a cell surface pattern recognition receptor (PRR). PRRs bind pathogen-associated molecular pattern (PAMPs), structures conserved among microbial species.


name: cytoplasmic pattern recognition receptor signaling pathway

description: The series of molecular signals initiated by the binding of a ligand from another organism to a cytoplasmic pattern recognition receptor (PRR). PRRs bind pathogen-associated molecular pattern (PAMPs), structures conserved among microbial species.


name: endosomal pattern recognition receptor signaling pathway

description: The series of molecular signals initiated by the binding of a ligand to an intracellular vesicle pattern recognition receptor (PRR). PRRs bind pathogen-associated molecular pattern (PAMPs), structures conserved among microbial species.


name: MyD88-dependent toll-like receptor signaling pathway

description: A toll-like receptor signaling pathway in which the MyD88 adaptor molecule mediates transduction of the signal. Toll-like receptors directly bind pattern motifs from a variety of microbial sources to initiate an innate immune response.


name: MyD88-independent toll-like receptor signaling pathway

description: A toll-like receptor signaling pathway not relying on the MyD88 adaptor molecule. Toll-like receptors directly bind pattern motifs from a variety of microbial sources to initiate innate an immune response.


name: immune response-activating signaling pathway

description: The series of molecular signals generated by a ligand binding to its receptor that lead to the activation or perpetuation of an immune response.


name: innate immune response-activating signaling pathway

description: The series of molecular signals generated by a ligand binding to its receptor that lead to the activation or perpetuation of an innate immune response.


name: regulation of antimicrobial humoral response

description: Any process that modulates the frequency, rate, or extent of an antimicrobial humoral response.


name: positive regulation of antimicrobial humoral response

description: Any process that activates or increases the frequency, rate, or extent of an antimicrobial humoral response.


name: regulation of myeloid leukocyte differentiation

description: Any process that modulates the frequency, rate, or extent of myeloid leukocyte differentiation.


name: negative regulation of myeloid leukocyte differentiation

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid leukocyte differentiation.


name: positive regulation of myeloid leukocyte differentiation

description: Any process that activates or increases the frequency, rate, or extent of myeloid leukocyte differentiation.


name: immune response-regulating signaling pathway

description: The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately leading to the activation, perpetuation, or inhibition of an immune response.


name: immune response-inhibiting signal transduction

description: The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately leading to inhibition of an immune response.


name: innate immune response-inhibiting signal transduction

description: The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately leading to inhibition of an innate immune response.


name: immune response-inhibiting cell surface receptor signaling pathway

description: The series of molecular signals initiated by an extracellular ligand binding to a receptor on the surface of the target cell capable of inhibiting an immune response.


name: immune response-regulating cell surface receptor signaling pathway

description: The series of molecular signals initiated by an extracellular ligand binding to a receptor on the surface of the target cell capable of activating, perpetuating, or inhibiting an immune response.


name: natural killer cell inhibitory signaling pathway

description: The series of molecular signals initiated by an extracellular ligand binding to a receptor on the surface of a natural killer cell capable of inhibiting an immune effector process contributing to an immune response.


T cell inhibitory signaling pathway

description: The series of molecular signals initiated by an extracellular ligand binding to a receptor on the surface of a T cell capable of inhibiting an immune effector process contributing to an immune response.


name: inhibitory killer cell immunoglobulin-like receptor signaling pathway

description: The series of molecular signals initiated by an extracellular ligand binding to a inhibitory killer cell immunoglobulin-like receptor capable of inhibiting an immune effector process contributing to an immune response.


name: inhibitory C-type lectin receptor signaling pathway

description: The series of molecular signals initiated by an extracellular ligand binding to an inhibitory C-type lectin receptor capable of inhibiting an immune effector process contributing to an immune response.


B cell inhibitory signaling pathway

description: The series of molecular signals initiated by an extracellular ligand binding to a receptor on the surface of a B cell capable of inhibiting an immune effector process contributing to an immune response.


name: Fc receptor mediated inhibitory signaling pathway

description: The series of molecular signals generated as a consequence of the binding of the Fc portion of an immunoglobulin by an Fc receptor capable of inhibiting an immune effector process contributing to an immune response. The Fc portion of an immunoglobulin is its C-terminal constant region.


antimicrobial peptide production

description: The synthesis or release of an antimicrobial peptide during an immune response, resulting in an increase in intracellular or extracellular levels. Such peptides may have protective properties against bacteria, fungi, viruses, or protozoa.


antimicrobial peptide secretion

description: The regulated release of an antimicrobial peptide from a cell or a tissue. Such peptides may have protective properties against bacteria, fungi, viruses, or protozoa.


name: antimicrobial peptide biosynthetic process

description: The chemical reactions and pathways resulting in the formation of an antimicrobial peptide. Such peptides may have protective properties against bacteria, fungi, viruses, or protozoa.


antibacterial peptide production

description: The synthesis or release of an antibacterial peptide during an immune response, resulting in an increase in intracellular or extracellular levels.


antibacterial peptide secretion

description: The regulated release of an antibacterial peptide from a cell or a tissue.


name: antibacterial peptide biosynthetic process

description: The chemical reactions and pathways resulting in the formation of an antibacterial peptide.


antifungal peptide production

description: The synthesis or release of an antifungal peptide during an immune response, resulting in an increase in intracellular or extracellular levels.


antifungal peptide secretion

description: The regulated release of an antifungal peptide from a cell or a tissue.


antifungal peptide biosynthetic process

description: The chemical reactions and pathways resulting in the formation of an antifungal peptide.


name: regulation of antimicrobial peptide production

description: Any process that modulates the frequency, rate, or extent of antimicrobial peptide production.


name: negative regulation of antimicrobial peptide production

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of antimicrobial peptide production.


name: regulation of antibacterial peptide production

description: Any process that modulates the frequency, rate, or extent of antibacterial peptide production.


name: negative regulation of antibacterial peptide production

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of antibacterial peptide production.


name: regulation of antifungal peptide production

description: Any process that modulates the frequency, rate, or extent of antifungal peptide production.


name: negative regulation of antifungal peptide production

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of antifungal peptide production.


peptide secretion

description: The controlled release of a peptide from a cell or a tissue.


regulation of peptide secretion

description: Any process that modulates the frequency, rate, or extent of peptide secretion.


name: negative regulation of peptide secretion

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of peptide secretion.


name: positive regulation of peptide secretion

description: Any process that activates or increases the frequency, rate, or extent of peptide secretion.


name: regulation of antimicrobial peptide secretion

description: Any process that modulates the frequency, rate, or extent of antimicrobial peptide secretion.


name: negative regulation of antimicrobial peptide secretion

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of antimicrobial peptide secretion.


name: positive regulation of antimicrobial peptide secretion

description: Any process that activates or increases the frequency, rate, or extent of antimicrobial peptide secretion.


name: regulation of antibacterial peptide secretion

description: Any process that modulates the frequency, rate, or extent of antibacterial peptide secretion.


name: negative regulation of antibacterial peptide secretion

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of antibacterial peptide secretion.


name: positive regulation of antibacterial peptide secretion

description: Any process that activates or increases the frequency, rate, or extent of antibacterial peptide secretion.


name: regulation of antifungal peptide secretion

description: Any process that modulates the frequency, rate, or extent of antifungal peptide secretion.


name: negative regulation of antifungal peptide secretion

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of antifungal peptide secretion.


name: positive regulation of antifungal peptide secretion

description: Any process that activates or increases the frequency, rate, or extent of antifungal peptide secretion.


name: positive regulation of antibacterial peptide production

description: Any process that activates or increases the frequency, rate, or extent of antibacterial peptide production.


name: positive regulation of antifungal peptide production

description: Any process that activates or increases the frequency, rate, or extent of antifungal peptide production.


name: regulation of antimicrobial peptide biosynthetic process

description: Any process that modulates the frequency, rate, or extent of antimicrobial peptide biosynthesis.


name: negative regulation of antimicrobial peptide biosynthetic process

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of antimicrobial peptide biosynthesis.


name: positive regulation of antimicrobial peptide biosynthetic process

description: Any process that activates or increases the frequency, rate, or extent of antimicrobial peptide biosynthesis.


name: regulation of antibacterial peptide biosynthetic process

description: Any process that modulates the frequency, rate, or extent of antibacterial peptide biosynthesis.


name: negative regulation of antibacterial peptide biosynthetic process

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of antibacterial peptide biosynthesis.


name: regulation of antifungal peptide biosynthetic process

description: Any process that modulates the frequency, rate, or extent of antifungal peptide biosynthesis.


name: negative regulation of antifungal peptide biosynthetic process

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of antifungal peptide biosynthesis.


name: biosynthetic process of antibacterial peptides active against Gram-negative bacteria

description: The chemical reactions and pathways resulting in the formation of an antibacterial peptide with activity against Gram-negative bacteria.


name: regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria

description: Any process that modulates the frequency, rate, or extent of biosynthesis of antibacterial peptides active against Gram-negative bacteria.


name: negative regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of biosynthesis of antibacterial peptides active against Gram-negative bacteria.


name: biosynthetic process of antibacterial peptides active against Gram-positive bacteria

description: The chemical reactions and pathways resulting in the formation of an antibacterial peptide with activity against Gram-positive bacteria.


name: regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria

description: Any process that modulates the frequency, rate, or extent of biosynthesis of antibacterial peptides active against Gram-positive bacteria.


name: negative regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of biosynthesis of antibacterial peptides active against Gram-positive bacteria.


regulation of adaptive immune response

description: Any process that modulates the frequency, rate, or extent of an adaptive immune response.


name: negative regulation of adaptive immune response

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of an adaptive immune response.


name: positive regulation of adaptive immune response

description: Any process that activates or increases the frequency, rate, or extent of an adaptive immune response.


name: regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains

description: Any process that modulates the frequency, rate, or extent of an adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains. An example of this process is found in the Gnathostomata.


name: negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of an adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains. An example of this process is found in the Gnathostomata.


name: positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains

description: Any process that activates or increases the frequency, rate, or extent of an adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains. An example of this process is found in the Gnathostomata.


name: regulation of T-helper 1 type immune response

description: Any process that modulates the frequency, rate, or extent of a T-helper 1 type immune response.


name: negative regulation of T-helper 1 type immune response

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of a T-helper 1 type immune response.


name: positive regulation of T-helper 1 type immune response

description: Any process that activates or increases the frequency, rate, or extent of a T-helper 1 type immune response.


regulation of type 2 immune response

description: Any process that modulates the frequency, rate, or extent of a type 2 immune response.


name: negative regulation of type 2 immune response

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of a type 2 immune response.


name: positive regulation of type 2 immune response

description: Any process that activates or increases the frequency, rate, or extent of a type 2 immune response.


name: regulation of response to biotic stimulus

description: Any process that modulates the frequency, rate, or extent of a response to biotic stimulus.


name: negative regulation of response to biotic stimulus

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of a response to biotic stimulus.


name: positive regulation of response to biotic stimulus

description: Any process that activates or increases the frequency, rate, or extent of a response to biotic stimulus.


regulation of response to tumor cell

description: Any process that modulates the frequency, rate, or extent of a response to tumor cell.


name: negative regulation of response to tumor cell

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of a response to tumor cell.


name: positive regulation of response to tumor cell

description: Any process that activates or increases the frequency, rate, or extent of a response to tumor cell.


name: regulation of immune response to tumor cell

description: Any process that modulates the frequency, rate, or extent of an immune response to tumor cell.


name: negative regulation of immune response to tumor cell

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of an immune response to tumor cell.


name: positive regulation of immune response to tumor cell

description: Any process that activates or increases the frequency, rate, or extent of an immune response to tumor cell.


name: regulation of T cell mediated immune response to tumor cell

description: Any process that modulates the frequency, rate, or extent of a T cell mediated immune response to tumor cell.


name: negative regulation of T cell mediated immune response to tumor cell

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of a T cell mediated immune response to tumor cell.


name: positive regulation of T cell mediated immune response to tumor cell

description: Any process that activates or increases the frequency, rate, or extent of a T cell mediated immune response to tumor cell.


name: regulation of tolerance induction to tumor cell

description: Any process that modulates the frequency, rate, or extent of tolerance induction to tumor cell.


name: negative regulation of tolerance induction to tumor cell

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of tolerance induction to tumor cell.


name: positive regulation of tolerance induction to tumor cell

description: Any process that activates or increases the frequency, rate, or extent of tolerance induction to tumor cell.


name: regulation of T cell tolerance induction to tumor cell

description: Any process that modulates the frequency, rate, or extent of T cell tolerance induction to tumor cell.


name: negative regulation of T cell tolerance induction to tumor cell

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell tolerance induction to tumor cell.


name: positive regulation of T cell tolerance induction to tumor cell

description: Any process that activates or increases the frequency, rate, or extent of T cell tolerance induction to tumor cell.


name: regulation of peripheral T cell tolerance induction

description: Any process that modulates the frequency, rate, or extent of peripheral T cell tolerance induction.


name: negative regulation of peripheral T cell tolerance induction

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of peripheral T cell tolerance induction.


name: positive regulation of peripheral T cell tolerance induction

description: Any process that activates or increases the frequency, rate, or extent of peripheral T cell tolerance induction.


name: regulation of T cell mediated cytotoxicity directed against tumor cell target

description: Any process that modulates the frequency, rate, or extent of T cell mediated cytotoxicity directed against a tumor cell target.


name: negative regulation of T cell mediated cytotoxicity directed against tumor cell target

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell mediated cytotoxicity directed against a tumor cell target.


name: positive regulation of T cell mediated cytotoxicity directed against tumor cell target

description: Any process that activates or increases the frequency, rate, or extent of T cell mediated cytotoxicity directed against a tumor cell target.


name: regulation of natural killer cell mediated immune response to tumor cell

description: Any process that modulates the frequency, rate, or extent of natural killer cell mediated immune response to a tumor cell.


name: negative regulation of natural killer cell mediated immune response to tumor cell

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of natural killer cell mediated immune response to a tumor cell.


name: positive regulation of natural killer cell mediated immune response to tumor cell

description: Any process that activates or increases the frequency, rate, or extent of natural killer cell mediated immune response to a tumor cell.


name: regulation of natural killer cell mediated cytotoxicity directed against tumor cell target

description: Any process that modulates the frequency, rate, or extent of natural killer cell mediated cytotoxicity directed against tumor cell target.


name: negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of natural killer cell mediated cytotoxicity directed against tumor cell target.


name: positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target

description: Any process that activates or increases the frequency, rate, or extent of natural killer cell mediated cytotoxicity directed against tumor cell target.


name: regulation of inflammatory response to antigenic stimulus

description: Any process that modulates the frequency, rate, or extent of an inflammatory response to an antigenic stimulus.


name: negative regulation of inflammatory response to antigenic stimulus

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of an inflammatory response to an antigenic stimulus.


name: positive regulation of inflammatory response to antigenic stimulus

description: Any process that activates or increases the frequency, rate, or extent of an inflammatory response to an antigenic stimulus.


name: regulation of acute inflammatory response to antigenic stimulus

description: Any process that modulates the frequency, rate, or extent of an acute inflammatory response to an antigenic stimulus.


name: negative regulation of acute inflammatory response to antigenic stimulus

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of an acute inflammatory response to an antigenic stimulus.


name: positive regulation of acute inflammatory response to antigenic stimulus

description: Any process that activates or increases the frequency, rate, or extent of an acute inflammatory response to an antigenic stimulus.


regulation of B cell deletion

description: Any process that modulates the frequency, rate, or extent of B cell deletion.


negative regulation of B cell deletion

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell deletion.


positive regulation of B cell deletion

description: Any process that activates or increases the frequency, rate, or extent of B cell deletion.


T cell anergy

description: Any process contributing to anergy in T cells, a state of functional inactivation which is part of T cell tolerance induction.


name: regulation of natural killer cell tolerance induction

description: Any process that modulates the frequency, rate, or extent of natural killer cell tolerance induction.


name: negative regulation of natural killer cell tolerance induction

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of natural killer cell tolerance induction.


name: positive regulation of natural killer cell tolerance induction

description: Any process that activates or increases the frequency, rate, or extent of natural killer cell tolerance induction.


name: regulation of chronic inflammatory response to antigenic stimulus

description: Any process that modulates the frequency, rate, or extent of a chronic inflammatory response to an antigenic stimulus.


name: negative regulation of chronic inflammatory response to antigenic stimulus

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of a chronic inflammatory response to an antigenic stimulus.


name: positive regulation of chronic inflammatory response to antigenic stimulus

description: Any process that activates or increases the frequency, rate, or extent of a chronic inflammatory response to an antigenic stimulus.


name: regulation of acute inflammatory response to non-antigenic stimulus

description: Any process that modulates the frequency, rate, or extent of an acute inflammatory response to a non-antigenic stimulus.


name: negative regulation of acute inflammatory response to non-antigenic stimulus

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of an acute inflammatory response to a non-antigenic stimulus.


name: positive regulation of acute inflammatory response to non-antigenic stimulus

description: Any process that activates or increases the frequency, rate, or extent of an acute inflammatory response to a non-antigenic stimulus.


name: regulation of chronic inflammatory response to non-antigenic stimulus

description: Any process that modulates the frequency, rate, or extent of a chronic inflammatory response to a non-antigenic stimulus.


name: negative regulation of chronic inflammatory response to non-antigenic stimulus

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of a chronic inflammatory response to a non-antigenic stimulus.


name: positive regulation of chronic inflammatory response to non-antigenic stimulus

description: Any process that activates or increases the frequency, rate, or extent of a chronic inflammatory response to a non-antigenic stimulus.


regulation of hypersensitivity

description: Any process that modulates the frequency, rate, or extent of hypersensitivity.


negative regulation of hypersensitivity

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of hypersensitivity.


positive regulation of hypersensitivity

description: Any process that activates or increases the frequency, rate, or extent of hypersensitivity.


name: regulation of myeloid leukocyte mediated immunity

description: Any process that modulates the frequency, rate, or extent of myeloid leukocyte mediated immunity.


name: negative regulation of myeloid leukocyte mediated immunity

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid leukocyte mediated immunity.


name: positive regulation of myeloid leukocyte mediated immunity

description: Any process that activates or increases the frequency, rate, or extent of myeloid leukocyte mediated immunity.


name: regulation of immunoglobulin mediated immune response

description: Any process that modulates the frequency, rate, or extent of an immunoglobulin mediated immune response.


name: negative regulation of immunoglobulin mediated immune response

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of an immunoglobulin mediated immune response.


name: positive regulation of immunoglobulin mediated immune response

description: Any process that activates or increases the frequency, rate, or extent of an immunoglobulin mediated immune response.


regulation of type II hypersensitivity

description: Any process that modulates the frequency, rate, or extent of type II hypersensitivity.


name: negative regulation of type II hypersensitivity

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of type II hypersensitivity.


name: positive regulation of type II hypersensitivity

description: Any process that activates or increases the frequency, rate, or extent of type II hypersensitivity.


name: regulation of central B cell tolerance induction

description: Any process that modulates the frequency, rate, or extent of central B cell tolerance induction.


name: negative regulation of central B cell tolerance induction

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of central B cell tolerance induction.


name: positive regulation of central B cell tolerance induction

description: Any process that activates or increases the frequency, rate, or extent of central B cell tolerance induction.


regulation of central B cell deletion

description: Any process that modulates the frequency, rate, or extent of central B cell deletion.


name: negative regulation of central B cell deletion

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of central B cell deletion.


name: positive regulation of central B cell deletion

description: Any process that activates or increases the frequency, rate, or extent of central B cell deletion.


mature B cell apoptotic process

description: Any apoptotic process in a B cell that is mature, having left the bone marrow.


regulation of B cell apoptotic process

description: Any process that modulates the frequency, rate, or extent of B cell apoptotic process.


name: negative regulation of B cell apoptotic process

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell apoptotic process.


name: positive regulation of B cell apoptotic process

description: Any process that activates or increases the frequency, rate, or extent of B cell apoptotic process.


name: regulation of mature B cell apoptotic process

description: Any process that modulates the frequency, rate, or extent of mature B cell apoptotic process.


name: negative regulation of mature B cell apoptotic process

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of mature B cell apoptotic process.


name: positive regulation of mature B cell apoptotic process

description: Any process that activates or increases the frequency, rate, or extent of mature B cell apoptotic process.


name: regulation of peripheral B cell deletion

description: Any process that modulates the frequency, rate, or extent of peripheral B cell deletion.


name: negative regulation of peripheral B cell deletion

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of peripheral B cell deletion.


name: positive regulation of peripheral B cell deletion

description: Any process that activates or increases the frequency, rate, or extent of peripheral B cell deletion.


regulation of lymphocyte anergy

description: Any process that modulates the frequency, rate, or extent of lymphocyte anergy.


name: negative regulation of lymphocyte anergy

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of lymphocyte anergy.


name: positive regulation of lymphocyte anergy

description: Any process that activates or increases the frequency, rate, or extent of lymphocyte anergy.


regulation of central B cell anergy

description: Any process that modulates the frequency, rate, or extent of central B cell anergy.


name: negative regulation of central B cell anergy

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of central B cell anergy.


name: positive regulation of central B cell anergy

description: Any process that activates or increases the frequency, rate, or extent of central B cell anergy.


regulation of peripheral B cell anergy

description: Any process that modulates the frequency, rate, or extent of peripheral B cell anergy.


name: negative regulation of peripheral B cell anergy

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of peripheral B cell anergy.


name: positive regulation of peripheral B cell anergy

description: Any process that activates or increases the frequency, rate, or extent of peripheral B cell anergy.


regulation of humoral immune response

description: Any process that modulates the frequency, rate, or extent of a humoral immune response.


name: negative regulation of humoral immune response

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of a humoral immune response.


name: positive regulation of humoral immune response

description: Any process that activates or increases the frequency, rate, or extent of a humoral immune response.


name: regulation of humoral immune response mediated by circulating immunoglobulin

description: Any process that modulates the frequency, rate, or extent of a humoral immune response mediated by circulating immunoglobulin.


name: negative regulation of humoral immune response mediated by circulating immunoglobulin

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of a humoral immune response mediated by circulating immunoglobulin.


name: positive regulation of humoral immune response mediated by circulating immunoglobulin

description: Any process that activates or increases the frequency, rate, or extent of a humoral immune response mediated by circulating immunoglobulin.


name: tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation

description: The process whereby a wobble base uridine residue in a tRNA is modified to 5-methoxycarbonylmethyl-2-thiouridine.


archaeosine-tRNA biosynthetic process

description: The chemical reactions and pathways involved in the biosynthesis of archaeosine, an archaea-specific modified base found at position 15 in the D-loop of certain archaeal tRNAs.


MECO complex

category: biolink:CellularComponent biolink:AnatomicalEntity biolink:PhysicalEssence biolink:OrganismalEntity biolink:SubjectOfInvestigation biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: A highly stable complex composed of the ATAC complex and the mediator complex (also called TRAP or MED). MECO binds and regulates the transcription of a subset of non-coding RNAs transcribed by RNA polymerase II.


trabecular meshwork development

description: The progression of the trabecular meshwork over time, from its formation to the mature structure. The trabecular meshwork is a fenestrated endothelial-like tissue situated at the intersection of the cornea and the iris. The trabecular meshwork provides drainage for the aqueous humor.


response to ischemia

description: Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a inadequate blood supply.


tendon sheath development

description: The process whose specific outcome is the progression of a tendon sheath over time, from its formation to the mature structure. A tendon sheath is a layer of membrane around a tendon. It permits the tendon to move.


lipid hydroxylation

description: The covalent attachment of a hydroxyl group to one or more fatty acids in a lipid.


desmosome organization

description: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a desmosome. A desmosome is a patch-like intercellular junction found in vertebrate tissues, consisting of parallel zones of two cell membranes, separated by an space of 25-35 nm, and having dense fibrillar plaques in the subjacent cytoplasm.


category: biolink:MolecularActivity biolink:Occurrent biolink:OntologyClass biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: Catalysis of the reaction: adenosine37 in tRNA + 2 reduced [2Fe-2S]-[ferredoxin] + 2 S-adenosyl-L-methionine = 2-methyladenosine37 in tRNA + 5'-deoxyadenosine + L-methionine + 2 oxidized [2Fe-2S]-[ferredoxin] + S-adenosyl-L-homocysteine.


bradykinin biosynthetic process

description: The chemical reactions and pathways resulting in the formation of the peptide hormone bradykinin.


tRNA 4-thiouridine biosynthesis

description: The processes whereby a uridine residue in a tRNA is converted to 4-thiouridine. Typically 4-thiouridine is found at position 8, in many transfer RNAs.


tRNA guanine ribose methylation

description: The process whereby a guanosine residue in a tRNA is methylated on the 2'-hydroxyl group of the ribose moiety.


tRNA N1-guanine methylation

description: The process whereby a guanine in tRNA is methylated at position N1 of the guanine.


tRNA N2-guanine methylation

description: The process whereby a guanine in a tRNA is methylated at the N2 position of guanine.


synoviocyte proliferation

description: The multiplication or reproduction of type B synoviocytes by cell division, resulting in the expansion of their population. A type B synoviocyte is a fibroblast-like cell found in synovial tissues.


tRNA m2,2-guanine biosynthesis

description: The process whereby a guanine residue in a transfer RNA is methylated twice at the N2 position.


tRNA dihydrouridine synthesis

description: The process whereby a uridine in a transfer RNA is converted to dihydrouridine.


cyclin K-CDK12 complex

description: A protein complex consisting of cyclin Kand cyclin-dependent kinase 12 (CDK12). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner.


cyclin K-CDK13 complex

description: A protein complex consisting of cyclin Kand cyclin-dependent kinase 13 (CDK13). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner.


tRNA C5-cytosine methylation

description: The process whereby a cytosine in a tRNA is methylated at position 5 of the cytosine.


name: tumor necrosis factor receptor superfamily complex

description: A receptor complex that contains one or more members of the tumor necrosis factor (TNF) receptor superfamily.


archaeosine synthase activity

description: Catalysis of the reaction: L-glutamine + 7-cyano-7-carbaguanine15 in tRNA + H2O = L-glutamate + archaeine15 in tRNA.


description: The attachment of a carbonyl group and a threonine to the amino group of the adenine residue immediately 3' of the anticodon, in tRNAs that decode ANN codons (where N is any base).


name: ceramide phosphoethanolamine synthase activity

description: Catalysis of the reaction: an N-acyl-sphingoid base + CDP-ethanolamine = an N-acyl-sphingoid 1-phosphoethanolamine + CMP + H+.


leukotriene-C(4) hydrolase

description: Catalysis of the reaction leukotriene C(4) + H2O= leukotriene D(4) + L-glutamate.


description: Catalysis of the reaction (4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione = 3-hydroxy-5-phosphonooxypentane-2,4-dione.


5'-deoxynucleotidase activity

description: Catalysis of the reaction: a 2'-deoxyribonucleoside 5'-phosphate + H2O = a 2'-deoxyribonucleoside + phosphate.


regionalization

description: The pattern specification process that results in the subdivision of an axis or axes in space to define an area or volume in which specific patterns of cell differentiation will take place or in which cells interpret a specific environment.


name: follicular fluid formation in ovarian follicle antrum involved in fused antrum stage

description: The ovulation cycle process in which one central cavity separating the oocyte/cumulus complex from mural granulosa and theca cells is formed as part of the fused antrum stage of oogenesis.


name: follicular fluid formation in ovarian follicle antrum involved in distinct antral spaces stage

description: The menstrual cycle process in which one central cavity separating the oocyte/cumulus complex from mural granulosa and theca cells is formed as part of the antral spaces stage of oogenesis.


name: follicular fluid formation in ovarian follicle antrum involved in scattered antral spaces stage

description: The menstrual cycle process in which one central cavity separating the oocyte/cumulus complex from mural granulosa and theca cells is formed as part of the scattered antral spaces stage of oogenesis.


name: developmental process involved in reproduction

description: A developmental process in which a progressive change in the state of some part of an organism, germline or somatic, specifically contributes to its ability to form offspring.


heart morphogenesis

description: The developmental process in which the heart is generated and organized. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.


system process

description: A multicellular organismal process carried out by any of the organs or tissues in an organ system. An organ system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a biological objective.


skeletal muscle contraction

description: A process in which force is generated within skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. In the skeletal muscle, the muscle contraction takes advantage of an ordered sarcomeric structure and in most cases it is under voluntary control.


voluntary skeletal muscle contraction

description: A process in which force is generated within voluntary skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. In the voluntary skeletal muscle, the muscle contraction takes advantage of an ordered sarcomeric structure and it is under voluntary control. Voluntary skeletal muscle is skeletal muscle that is under conscious control.


involuntary skeletal muscle contraction

description: A process in which force is generated within involuntary skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. Involuntary skeletal muscle is skeletal muscle that is not under conscious control.


muscle system process

description: A organ system process carried out at the level of a muscle. Muscle tissue is composed of contractile cells or fibers.


circulatory system process

description: A organ system process carried out by any of the organs or tissues of the circulatory system. The circulatory system is an organ system that moves extracellular fluids to and from tissue within a multicellular organism.


renal system process

description: A organ system process carried out by any of the organs or tissues of the renal system. The renal system maintains fluid balance, and contributes to electrolyte balance, acid/base balance, and disposal of nitrogenous waste products. In humans, the renal system comprises a pair of kidneys, a pair of ureters, urinary bladder, urethra, sphincter muscle and associated blood vessels; in other species, the renal system may comprise related structures (e.g., nephrocytes and malpighian tubules in Drosophila).


heart process

description: A circulatory system process carried out by the heart. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.


respiratory system process

description: A process carried out by the organs or tissues of the respiratory system. The respiratory system is an organ system responsible for respiratory gaseous exchange.


lymph circulation

description: The flow of lymph through the body of an animal.


vascular process in circulatory system

description: A circulatory process that occurs at the level of the vasculature.


name: central nervous system control of baroreceptor feedback

description: The neurological process in which nerve impulses arising in the aorta or the carotid sinuses travel to the medulla and reach the nucleus of tractus solaris.


name: detection of reduced oxygen by chemoreceptor signaling

description: The process in which information about the levels of oxygen are received and are converted to a molecular signal by chemoreceptors in the carotid bodies and the aortic bodies.


name: detection of increased carbon dioxide by chemoreceptor signaling

description: The process in which information about the levels of carbon dioxide are received and are converted to a molecular signal by chemoreceptors in the carotid bodies and the aortic bodies.


name: detection of pH by chemoreceptor signaling

description: The process in which information about the levels of hydrogen ions are received and are converted to a molecular signal by chemoreceptors.


name: baroreceptor detection of increased arterial stretch

description: The series of events by which an increase in diameter of an artery is detected and converted to a molecular signal.


name: baroreceptor detection of decreased arterial stretch

description: The series of events by which a decrease in diameter of an artery is detected and converted to a molecular signal.


name: regulation of systemic arterial blood pressure by baroreceptor feedback

description: The neural regulation of blood pressure in which baroreceptors sense the amount of stretch occurring in vessels and respond to the input via central nervous system control.


name: regulation of systemic arterial blood pressure by aortic arch baroreceptor feedback

description: The process that modulates blood pressure by sensing the amount of stretch occurring in the aorta and responding to the input via central nervous system control.


name: regulation of systemic arterial blood pressure by carotid body chemoreceptor signaling

description: The process that modulates blood pressure by the action of chemoreceptors found in the carotid bodies and their resultant modulation of the vasomotor center. Chemoreceptors respond to oxygen, carbon dioxide and hydrogen ions.


name: regulation of systemic arterial blood pressure by aortic body chemoreceptor signaling

description: The process that modulates blood pressure by the action of chemoreceptors found in the aortic bodies and their resultant modulation of the vasomotor center. Chemoreceptors respond to oxygen, carbon dioxide and hydrogen ions.


name: detection of hypoxic conditions in blood by carotid body chemoreceptor signaling

description: The process in which information about a lack of oxygen are received and are converted to a molecular signal by chemoreceptors in the carotid bodies.


detection of hydrogen ion

description: The series of events in which a hydrogen ion stimulus is received by a cell and converted into a molecular signal.


detection of carbon dioxide

description: The series of events in which a carbon dioxide stimulus is received by a cell and converted into a molecular signal.


detection of oxygen

description: The series of events in which an oxygen stimulus is received by a cell and converted into a molecular signal.


name: detection of hypoxic conditions in blood by aortic body chemoreceptor signaling

description: The process in which information about a lack of oxygen are received and are converted to a molecular signal by chemoreceptors in the aortic bodies.


name: detection of increased carbon dioxide by aortic body chemoreceptor signaling

description: The process in which information about the levels of carbon dioxide are received and are converted to a molecular signal by chemoreceptors in an aortic body.


name: detection of increased carbon dioxide by carotid body chemoreceptor signaling

description: The process in which information about the levels of carbon dioxide are received and are converted to a molecular signal by chemoreceptors in a carotid body.


name: detection of pH by aortic body chemoreceptor signaling

description: The process in which information about the levels of hydrogen ions are received and are converted to a molecular signal by chemoreceptors in an aortic body.


name: detection of pH by carotid body chemoreceptor signaling

description: The process in which information about the levels of hydrogen ions are received and are converted to a molecular signal by chemoreceptors in a carotid body.


name: detection of reduced oxygen by aortic body chemoreceptor signaling

description: The process in which information about the levels of oxygen are received and are converted to a molecular signal by chemoreceptors in an aortic body.


name: detection of reduced oxygen by carotid body chemoreceptor signaling

description: The process in which information about the levels of oxygen are received and are converted to a molecular signal by chemoreceptors in a carotid body.


name: excitation of vasomotor center by aortic body chemoreceptor signaling

description: The process in which the molecular signal from an aortic body is relayed to the vasomotor center, causing it to signal an increase arterial pressure.


name: excitation of vasomotor center by carotid body chemoreceptor signaling

description: The process in which the molecular signal from a carotid body is relayed to the vasomotor center, causing it to signal an increase arterial pressure.


name: vasoconstriction of artery involved in carotid body chemoreceptor response to lowering of systemic arterial blood pressure

description: A process that is triggered by carotid body-vasomotor excitation and results in a decrease in the diameter of an artery during the chemoreceptor response to decreased blood pressure.


name: vasoconstriction of artery involved in aortic body chemoreceptor response to lowering of systemic arterial blood pressure

description: A process that is triggered by aortic body-vasomotor excitation and results in a decrease in the diameter of an artery during the chemoreceptor response to decreased blood pressure.


name: regulation of systemic arterial blood pressure mediated by a chemical signal

description: The regulation of blood pressure mediated by biochemical signaling: hormonal, autocrine or paracrine.


name: regulation of systemic arterial blood pressure by physical factors

description: The regulation of blood pressure mediated by detection of forces within the circulatory system.


name: regulation of systemic arterial blood pressure by stress relaxation

description: The intrinsic circulatory process resulting from stress relaxation that modulates the force with which blood travels through the systemic arterial circulatory system. Stress relaxation is the adaptation of vessels to a new size as a result of changes in pressure in storage areas such as veins, the liver, the spleen, and the lungs.


name: regulation of systemic arterial blood pressure by epinephrine

description: The regulation of blood pressure mediated by the catecholamine signaling molecule epinephrine.


name: regulation of systemic arterial blood pressure by norepinephrine

description: The regulation of blood pressure mediated by the catecholamine signaling molecule norepinephrine.


name: regulation of systemic arterial blood pressure by capillary fluid shift

description: The intrinsic circulatory process resulting from capillary fluid shift that modulates the force with which blood travels through the systemic arterial circulatory system. Capillary fluid shift is the movement of fluid across the capillary membrane between the blood and the interstitial fluid compartment.


name: regulation of systemic arterial blood pressure by atrial natriuretic peptide

description: The regulation of blood pressure mediated by the signaling molecule atrial natriuretic peptide.


angiotensin-mediated drinking behavior

description: The drinking behavior that is mediated by the action of angiotensin in the brain. Angiotensin stimulates the brain centers that control thirst.


name: circadian regulation of systemic arterial blood pressure

description: Any process in which an organism modulates its blood pressure at different values with a regularity of approximately 24 hours.


circadian regulation of heart rate

description: Any process in which an organism modulates its heart rate at different values with a regularity of approximately 24 hours.


name: circadian regulation of systemic arterial blood pressure by the suprachiasmatic nucleus

description: The process in which the suprachiasmatic nucleus modulates blood pressure at different values with a regularity of approximately 24 hours.


name: circadian regulation of heart rate by the suprachiasmatic nucleus

description: The process in which the suprachiasmatic nucleus modulates heart rate at different values with a regularity of approximately 24 hours.


name: regulation of vascular associated smooth muscle contraction

description: Any process that increases the frequency, rate or extent of vascular smooth muscle contraction.


name: regulation of the force of heart contraction by chemical signal

description: The regulation of the force of heart muscle contraction mediated by chemical signaling, hormonal, autocrine or paracrine.


name: hormonal regulation of the force of heart contraction

description: The process in which the hormones modulates the force of heart muscle contraction. A hormone is one of a group of substances formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells, in the same organism, upon which they have a specific regulatory action.


name: positive regulation of the force of heart contraction by epinephrine

description: The process in which the secretion of epinephrine into the bloodstream or released from nerve endings modulates the force of heart muscle contraction.


name: negative regulation of the force of heart contraction by acetylcholine

description: The process in which acetylcholine released from vagus nerve endings binds to muscarinic receptors and decreases the force of heart muscle contraction.


name: positive regulation of the force of heart contraction by norepinephrine

description: The process in which the secretion of norepinephrine into the bloodstream or released from nerve endings modulates the force of heart musclecontraction.


name: regulation of heart rate by chemical signal

description: The regulation of the rate of heart contraction mediated by chemical signaling, hormonal, autocrine or paracrine.


name: negative regulation of heart rate by acetylcholine

description: The process in which acetylcholine released from vagus nerve endings binds to muscarinic receptors on the pacemaker cells and decreases the rate of heart muscle contraction.


regulation of heart rate by hormone

description: The process in which the hormones modulates the rate of heart muscle contraction. A hormone is one of a group of substances formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells, in the same organism, upon which they have a specific regulatory action.


name: positive regulation of heart rate by epinephrine

description: The process in which the secretion of epinephrine into the bloodstream or released from nerve endings increases the rate of heart muscle contraction.


name: positive regulation of heart rate by norepinephrine

description: The process in which the secretion of norepinephrine into the bloodstream or released from nerve endings increases the rate of heart muscle contraction.


name: circadian regulation of systemic arterial blood pressure by hormone

description: The process in which hormones modulate the force with which blood passes through the circulatory system contributing to different values of blood pressure oscillating with a regularity of approximately 24 hours. A hormone is one of a group of substances formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells, in the same organism, upon which they have a specific regulatory action.


name: regulation of systemic arterial blood pressure by acetylcholine

description: The regulation of blood pressure mediated by acetylcholine signaling. Acetylcholine is an acetic acid ester of the organic base choline and functions as a neurotransmitter.


name: acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure

description: The process in which acetylcholine signaling causes vasodilation, resulting in a change in blood pressure.


name: regulation of systemic arterial blood pressure by neurotransmitter

description: The regulation of blood pressure mediated by a neurotransmitter. A neurotransmitter is any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell.


name: renal system process involved in regulation of systemic arterial blood pressure

description: Renal process that modulates the force with which blood travels through the circulatory system. The process is controlled by a balance of processes that increase pressure and decrease pressure.


name: renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure

description: The renal process that modulates the force with which blood travels through the circulatory system, by impeding blood flow through the peripheral vasculature.


name: regulation of systemic arterial blood pressure

description: The process that modulates the force with which blood travels through the systemic arterial circulatory system. The process is controlled by a balance of processes that increase pressure and decrease pressure.


name: renal vasodilation of the peripheral vascular system involved in regulation of systemic arterial blood pressure

description: The renal process that modulates the force with which blood travels through the circulatory system, by vasodilation of the peripheral vascular system.


name: regulation of systemic arterial blood pressure by renin-angiotensin

description: The process in which renin-angiotensin modulates the force with which blood passes through the circulatory system.


name: negative regulation of renal output by angiotensin

description: The process in which angiotensin directly decreases the rate of natriuresis and diuresis in the kidney.


name: positive regulation of systemic arterial blood pressure

description: The process that increases the force with which blood travels through the systemic arterial circulatory system.


name: negative regulation of systemic arterial blood pressure

description: The process that reduces the force with which blood travels through the systemic arterial circulatory system.


name: regulation of systemic arterial blood pressure by local renal renin-angiotensin

description: The process in which angiotensinogen metabolites in the kidney modulate the force with which blood passes through the renal circulatory system. The process begins when renin cleaves angiotensinogen.


name: positive regulation of the force of heart contraction by neuronal epinephrine

description: The process in which the release of epinephrine from nerve endings modulates the force of heart muscle contraction.


name: positive regulation of the force of heart contraction by circulating epinephrine

description: The process in which the secretion of epinephrine into the bloodstream modulates the force of heart muscle contraction.


name: positive regulation of the force of heart contraction by circulating epinephrine-norepinephrine

description: Any process that increases the force with which the cardiac muscles of the heart pump blood through the circulatory system as a result of the presence of epinephrine or norepinephrine in the bloodstream.


name: positive regulation of the force of heart contraction by neuronal epinephrine-norepinephrine

description: Any process that increases the force with which the cardiac muscles of the heart pump blood through the circulatory system as a result of the presence of epinephrine or norepinephrine released from the nerve endings.


renal water homeostasis

description: Renal process involved in the maintenance of an internal steady state of water in the body.


renal water retention

description: The process in which renal water excretion is decreased.


regulation of glomerular filtration

description: Any process that modulates the frequency, rate or extent of glomerular filtration. Glomerular filtration is the process in which blood is filtered by the glomerulus into the renal tubule.


glomerular filtration

description: The process in which plasma is filtered through the glomerular membrane which consists of capillary endothelial cells, the basement membrane, and epithelial cells. The glomerular filtrate is the same as plasma except it has no significant amount of protein.


pressure natriuresis

description: The process in which the volume of blood increases renal pressure and thereby results in both an increase in urine volume (diuresis) and an increase in the amount of sodium excreted in the urine (natriuresis).


renal sodium ion transport

description: The directed movement of sodium ions (Na+) by the renal system.


renal water transport

description: The directed movement of water (H2O) by the renal system.


tubuloglomerular feedback

description: The process in which blood volume is regulated due to a change in the rate of glomerular filtration. This is accomplished by a feedback mechanism that senses changes in the juxtaglomerular apparatus.


name: positive regulation of the force of heart contraction by chemical signal

description: Any process which increases the force of heart muscle contraction mediated by chemical signaling, hormonal, autocrine or paracrine.


name: regulation of systemic arterial blood pressure by endothelin

description: The process in which endothelin modulates the force with which blood passes through the circulatory system. Endothelin is a hormone that is released by the endothelium, and it is a vasoconstrictor.


name: regulation of systemic arterial blood pressure by circulatory epinephrine-norepinephrine

description: The process in which epinephrine-norepinephrine modulate the force with which blood passes through the circulatory system.


name: positive regulation of glomerular filtration

description: Any process that activates or increases the frequency, rate or extent of glomerular filtration. Glomerular filtration is the process whereby blood is filtered by the glomerulus into the renal tubule.