alpha-keto amide reductase activity

description: Catalysis of the reaction: alpha-keto amide + 2 H+ (from donor) = (R)-hydroxy amide. Alpha-keto amides are of the form R-CO-CONH2, where R may be aromatic or aliphatic.


alpha-keto ester reductase activity

category: biolink:MolecularActivity biolink:Occurrent biolink:OntologyClass biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: Catalysis of the reaction: alpha-keto ester + 2 H+ (from donor) = (R)-hydroxy ester. Alpha-keto esters are of the form R(1)-CO-CO-O-R(2), where the R groups may be aromatic or aliphatic.


beta-glucan metabolic process

category: biolink:BiologicalProcess biolink:Occurrent biolink:OntologyClass biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: The chemical reactions and pathways involving beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds.


beta-glucan biosynthetic process

description: The chemical reactions and pathways resulting in the formation of beta-glucans.


beta-glucan catabolic process

description: The chemical reactions and pathways resulting in the breakdown of beta-glucans.


chromosome organization

description: A process that is carried out at the cellular level that results in the assembly, arrangement of constituent parts, or disassembly of chromosomes, structures composed of a very long molecule of DNA and associated proteins that carries hereditary information. This term covers covalent modifications at the molecular level as well as spatial relationships among the major components of a chromosome.


name: fungal-type cell wall polysaccharide biosynthetic process

description: The chemical reactions and pathways resulting in the formation of the polysaccharides which make up the fungal-type cell wall.


name: regulation of release of sequestered calcium ion into cytosol

description: Any process that modulates the frequency, rate or extent of the release into the cytosolic compartment of calcium ions sequestered in the endoplasmic reticulum or mitochondria.


name: negative regulation of release of sequestered calcium ion into cytosol

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the release into the cytosolic compartment of calcium ions sequestered in the endoplasmic reticulum or mitochondria.


name: positive regulation of release of sequestered calcium ion into cytosol

description: Any process that activates or increases the frequency, rate or extent of the release into the cytosolic compartment of calcium ions sequestered in the endoplasmic reticulum or mitochondria.


name: regulation of sequestering of calcium ion

description: Any process that modulates the frequency, rate or extent of the binding or confining calcium ions such that they are separated from other components of a biological system.


name: negative regulation of sequestering of calcium ion

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the binding or confining calcium ions such that they are separated from other components of a biological system.


name: positive regulation of sequestering of calcium ion

description: Any process that activates or increases the frequency, rate or extent of the binding or confining calcium ions such that they are separated from other components of a biological system.


cell cortex of cell tip

category: biolink:CellularComponent biolink:AnatomicalEntity biolink:PhysicalEssence biolink:OrganismalEntity biolink:SubjectOfInvestigation biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: The region directly beneath the plasma membrane at the cell tip. The cell tip is the region at either end of the longest axis of a cylindrical or elongated cell.


cell tip

description: The region at the end of the longest axis of a cylindrical or elongated cell.


NAD binding

description: Binding to nicotinamide adenine dinucleotide, a coenzyme involved in many redox and biosynthetic reactions; binding may be to either the oxidized form, NAD+, or the reduced form, NADH.


protein homotetramerization

description: The formation of a protein homotetramer, a macromolecular structure consisting of four noncovalently associated identical subunits.


protein heterotetramerization

description: The formation of a protein heterotetramer, a macromolecular structure consisting of four noncovalently associated subunits, of which not all are identical.


protein heterooligomerization

description: The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of component monomers that are not all identical. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.


nuclear pore complex assembly

description: The aggregation, arrangement and bonding together of a set of components to form a nuclear pore complex.


establishment of spindle localization

description: The directed movement of the spindle to a specific location in the cell.


establishment of spindle orientation

description: Any process that set the alignment of spindle relative to other cellular structures.


name: establishment of meiotic spindle localization

description: The cell cycle process in which the directed movement of the meiotic spindle to a specific location in the cell occurs.


name: establishment of meiotic spindle orientation

description: Any process that set the alignment of meiotic spindle relative to other cellular structures.


centrosome duplication

description: The replication of a centrosome, a structure comprised of a pair of centrioles and peri-centriolar material from which a microtubule spindle apparatus is organized.


centrosome separation

description: The process in which duplicated centrosome components move away from each other. The centriole pair within each centrosome becomes part of a separate microtubule organizing center that nucleates a radial array of microtubules called an aster. The two asters move to opposite sides of the nucleus to form the two poles of the mitotic spindle.


spindle pole body organization

description: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the spindle pole body (SPB). The SPB is the microtubule organizing center in fungi, and is functionally homologous to the animal cell centrosome.


cell division

description: The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells.


regulation of cell division

description: Any process that modulates the frequency, rate or extent of the physical partitioning and separation of a cell into daughter cells.


name: establishment of chromosome localization

description: The directed movement of a chromosome to a specific location.


chromosome separation

description: The cell cycle process in which paired chromosomes are detached from each other. Chromosome separation begins with the release of cohesin complexes from chromosomes; in budding yeast, this includes the cleavage of cohesin complexes along the chromosome arms, followed by the separation of the centromeric regions. Chromosome separation also includes formation of chromatid axes mediated by condensins, and ends with the disentangling of inter-sister catenation catalyzed by topoisomerase II (topo II).


name: chromosome movement towards spindle pole

description: The directed movement of chromosomes in the center of the spindle towards the spindle poles, mediated by the shortening of microtubules attached to the chromosomes.


mitotic sister chromatid separation

description: The process in which sister chromatids are physically detached from each other during mitosis.


meiotic chromosome separation

description: The process in which chromosomes are physically detached from each other during meiosis.


male meiosis chromosome separation

description: The process in which paired chromosomes are physically detached from each other during male meiosis.


female meiosis chromosome separation

description: The process in which paired chromosomes are physically detached from each other during female meiosis.


metaphase chromosome alignment

description: A chromosome localization process whereby chromosomes are positioned in a specific order and orientation at the metaphase plate (spindle equator), during chromosome segregation. This alignment ensures that each daughter cell will receive the correct number of chromosomes during cell division.


meiotic metaphase chromosome alignment

description: A chromosome localization process whereby chromosomes are positioned in a specific order and orientation at the metaphase plate (spindle equator), during meiotic chromosome segregation. This alignment ensures that each daughter cell will receive the correct number of chromosomes during cell division.


name: attachment of mitotic spindle microtubules to kinetochore

description: The cellular process in which spindle microtubules become physically associated with the proteins making up the kinetochore complex in mitosis.


name: attachment of meiotic spindle microtubules to kinetochore

description: The cellular process in which spindle microtubules become physically associated with the proteins making up the kinetochore complex in meiosis.


G1 phase

description: The cell cycle 'gap' phase which is the interval between the completion of DNA segregation (usually by mitosis or meiosis) and the beginning of DNA synthesis.


G2 phase

description: The cell cycle 'gap' phase which is the interval between the completion of DNA synthesis and the beginning of DNA segregation (usually by mitosis or meiosis).


S phase

description: The cell cycle phase, following G1, during which DNA synthesis takes place.


meiotic cell cycle

description: Progression through the phases of the meiotic cell cycle, in which canonically a cell replicates to produce four offspring with half the chromosomal content of the progenitor cell via two nuclear divisions.


anaphase

description: The cell cycle phase, following metaphase, during which the chromosomes separate and migrate towards the poles of the spindle.


metaphase

description: The cell cycle phase, following prophase or prometaphase in higher eukaryotes, during which chromosomes become aligned on the equatorial plate of the cell.


prophase

description: The cell cycle phase which is the first stage of M phase of meiosis and mitosis and during which chromosomes condense and the two daughter centrioles and their asters migrate toward the poles of the cell.


interphase

description: The cell cycle phase following cytokinesis which begins with G1 phase, proceeds through S phase and G2 phase and ends when prophase of meiosis or mitosis begins. During interphase the cell readies itself for meiosis or mitosis and the replication of its DNA occurs.


telophase

description: The cell cycle phase which follows anaphase during M phase of mitosis and meiosis and during which the chromosomes arrive at the poles of the cell and the division of the cytoplasm starts.


meiotic M phase

description: A cell cycle phase during which nuclear division occurs, and which is comprises the phases: prophase, metaphase, anaphase and telophase and occurs as part of a meiotic cell cycle.


meiotic interphase

description: The cell cycle phase which begins after cytokinesis and ends when meiotic prophase begins. Meiotic cells have an interphase after each meiotic division, but only interphase I involves replication of the cell's DNA.


mitotic interphase

description: The cell cycle phase following cytokinesis which begins with G1 phase, proceeds through S phase and G2 phase and ends when mitotic prophase begins. During interphase the cell readies itself for mitosis and the replication of its DNA occurs.


meiotic G1 phase

description: The cell cycle 'gap' phase which is the interval between the completion of DNA segregation by meiosis and the beginning of DNA synthesis.


meiotic G2 phase

description: The cell cycle 'gap' phase which is the interval between the completion of DNA synthesis and the beginning of DNA segregation by meiosis.


meiotic S phase

description: The cell cycle phase, following G1, during which DNA synthesis takes place as part of a meiotic cell cycle.


meiotic nuclear membrane reassembly

description: The cell cycle process in which the reformation of the nuclear membranes during meiosis occurs.


meiosis I nuclear membrane reassembly

description: The reformation of the nuclear membranes during meiosis I.


meiosis II nuclear membrane reassembly

description: The reformation of the nuclear membrane during meiosis II.


regulation of hydrolase activity

description: Any process that modulates the frequency, rate or extent of hydrolase activity, the catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3.


amitosis

description: Nuclear division that occurs by simple constriction of the nucleus without chromosome condensation or spindle formation.


regulation of transferase activity

description: Any process that modulates the frequency, rate or extent of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2.


regulation of lyase activity

description: Any process that modulates the frequency, rate or extent of lyase activity, the catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond. They differ from other enzymes in that two substrates are involved in one reaction direction, but only one in the other direction. When acting on the single substrate, a molecule is eliminated and this generates either a new double bond or a new ring.


regulation of ligase activity

description: Any process that modulates the frequency, rate or extent of ligase activity, the catalysis of the ligation of two substances with concomitant breaking of a diphosphate linkage, usually in a nucleoside triphosphate. Ligase is the systematic name for any enzyme of EC class 6.


regulation of oxidoreductase activity

description: Any process that modulates the frequency, rate or extent of oxidoreductase activity, the catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.


name: regulation of cyclic-nucleotide phosphodiesterase activity

description: Any process that modulates the frequency, rate or extent of cyclic nucleotide phosphodiesterase activity, the catalysis of the reaction: nucleotide 3',5'-cyclic phosphate + H2O = nucleotide 5'-phosphate.


name: positive regulation of cyclic-nucleotide phosphodiesterase activity

description: Any process that activates or increases the frequency, rate or extent of cyclic nucleotide phosphodiesterase activity, the catalysis of the reaction: nucleotide 3',5'-cyclic phosphate + H2O = nucleotide 5'-phosphate.


name: negative regulation of cyclic-nucleotide phosphodiesterase activity

description: Any process that stops or reduces the rate of cyclic nucleotide phosphodiesterase activity, the catalysis of the reaction: nucleotide 3',5'-cyclic phosphate + H2O = nucleotide 5'-phosphate.


name: positive regulation of hydrolase activity

description: Any process that activates or increases the frequency, rate or extent of hydrolase activity, the catalysis of the hydrolysis of various bonds.


name: negative regulation of hydrolase activity

description: Any process that stops or reduces the rate of hydrolase activity, the catalysis of the hydrolysis of various bonds.


name: positive regulation of transferase activity

description: Any process that activates or increases the frequency, rate or extent of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from a donor compound to an acceptor.


name: negative regulation of transferase activity

description: Any process that stops or reduces the rate of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from a donor compound to an acceptor.


positive regulation of lyase activity

description: Any process that activates or increases the frequency, rate or extent of lyase activity, the catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond.


negative regulation of lyase activity

description: Any process that stops or reduces the rate of lyase activity, the catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond.


positive regulation of ligase activity

description: Any process that activates or increases the frequency, rate or extent of ligase activity, the catalysis of the ligation of two substances with concomitant breaking of a diphosphate linkage, usually in a nucleoside triphosphate.


negative regulation of ligase activity

description: Any process that stops or reduces the rate of ligase activity, the catalysis of the ligation of two substances with concomitant breaking of a diphosphate linkage, usually in a nucleoside triphosphate.


name: positive regulation of oxidoreductase activity

description: Any process that activates or increases the frequency, rate or extent of oxidoreductase activity, the catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered.


name: negative regulation of oxidoreductase activity

description: Any process that stops or reduces the rate of oxidoreductase activity, the catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered.


name: proprioception involved in equilibrioception

description: The series of events contributing to equilibrioception by which an organism senses the position, location, orientation, and movement of the body and its parts. Proprioception plays an important role in the ability of an organism to perceive its orientation with respect to gravity.


name: visual perception involved in equilibrioception

description: The series of events during equilibrioception required for an organism to receive a visual stimulus, convert it to a molecular signal, and recognize and characterize the signal. Visual input plays an important role in the ability of an organism to perceive its orientation with respect to gravity.


name: peptidoglycan-protein cross-linking via L-alanyl-pentaglycyl-murein

description: The process of linking a protein to peptidoglycan via a carboxy terminal alanine carboxyl group through a pentaglycyl peptide to the lysine or diaminopimelic acid of the peptidoglycan.


description: The formylation of the N-terminal proline of proteins to form the derivative N-formylproline.


name: cellular response to potassium ion starvation

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of potassium ions.


protein decanoylation

description: The modification of a protein amino acid by formation of an ester or amide with decanoic acid.


peptidyl-serine decanoylation

description: The decanoylation of peptidyl-serine to form peptidyl-O3-decanoyl-L-serine, typical of the protein ghrelin.


peptidyl-threonine octanoylation

description: The octanoylation of peptidyl-threonine to form peptidyl-O3-octanoyl-L-threonine, typical of the protein ghrelin.


peptidyl-threonine decanoylation

description: The decanoylation of peptidyl-threonine to form peptidyl-O3-decanoyl-L-threonine, typical of the protein ghrelin.


muscle alpha-actinin binding

description: Binding to muscle isoforms of actinin. Muscle alpha-actinin isoforms are found in skeletal and cardiac muscle and are localized to the Z-disc.


FATZ binding

description: Binding to a member of the FATZ family of proteins, filamin-, actinin-, and telethonin-binding proteins of the Z-disc of striated muscle. FATZ proteins are located in the Z-disc of the sarcomere and are involved in a complex network of interactions with other Z-band components.


description: Catalysis of the transfer of ethanolamine phosphate to a mannose residue in the GPI lipid precursor.


serotonin binding

description: Binding to serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties.


epinephrine binding

description: Binding to epinephrine, a hormone produced by the medulla of the adrenal glands that increases heart activity, improves the power and prolongs the action of muscles, and increases the rate and depth of breathing. It is synthesized by the methylation of norepinephrine.


norepinephrine binding

description: Binding to norepinephrine, (3,4-dihydroxyphenyl-2-aminoethanol), a hormone secreted by the adrenal medulla and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts of the CNS. It is also the biosynthetic precursor of epinephrine.


histamine binding

description: Binding to histamine, a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans.


kinetochore assembly

description: The aggregation, arrangement and bonding together of a set of components to form the kinetochore, a multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules.


kinetochore organization

description: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the kinetochore, a multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules.


response to glucocorticoid

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucocorticoid stimulus. Glucocorticoids are hormonal C21 corticosteroids synthesized from cholesterol with the ability to bind with the cortisol receptor and trigger similar effects. Glucocorticoids act primarily on carbohydrate and protein metabolism, and have anti-inflammatory effects.


response to mineralocorticoid

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mineralocorticoid stimulus. Mineralocorticoids are hormonal C21 corticosteroids synthesized from cholesterol and characterized by their similarity to aldosterone. Mineralocorticoids act primarily on water and electrolyte balance.


name: regulation of neurotrophin TRK receptor signaling pathway

description: Any process that modulates the frequency, rate or extent of the neurotrophin TRK receptor signaling pathway.


name: negative regulation of neurotrophin TRK receptor signaling pathway

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the neurotrophin TRK receptor signaling pathway.


name: positive regulation of neurotrophin TRK receptor signaling pathway

description: Any process that activates or increases the frequency, rate or extent of the neurotrophin TRK receptor signaling pathway.


tRNA acetylation

description: The modification of tRNA structure by addition of an acetyl group to tRNA. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid.


tRNA N-acetyltransferase activity

description: Catalysis of the reaction: a cytidine in tRNA + acetyl-CoA + ATP + H2O = ADP + an N4-acetylcytidine in tRNA + CoA + H+ + phosphate.


alpha-actinin binding

description: Binding to alpha-actinin, one of a family of proteins that cross-link F-actin as antiparallel homodimers. Alpha-actinin has a molecular mass of 93-103 KDa; at the N-terminus there are two calponin homology domains, at the C-terminus there are two EF-hands. These two domains are connected by the rod domain. This domain is formed by triple-helical spectrin repeats.


name: regulation of nerve growth factor receptor activity

description: Any process that modulates the frequency, rate or extent of the activity of the nerve growth factor (NGF) receptor.


name: negative regulation of nerve growth factor receptor activity

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of the nerve growth factor (NGF) receptor.


name: positive regulation of nerve growth factor receptor activity

description: Any process that activates or increases the frequency, rate or extent of the activity of the nerve growth factor (NGF) receptor.


BH domain binding

description: Binding to a Bcl-2 homology (BH) protein domain. Bcl-2-related proteins share homology in one to four conserved regions designated the Bcl-2 homology (BH) domains BH1, BH2, BH3 and BH4. These domains contribute at multiple levels to the function of these proteins in cell death and survival. Anti-apoptotic members of the Bcl-2 family have four BH domains (BH1-BH4). Pro-apoptotic members have fewer BH domains.


CH domain binding

description: Binding to a calponin homology protein domain, a domain of 100 residues that occurs in signaling and cytoskeletal proteins.


neuron apoptotic process

description: Any apoptotic process in a neuron, the basic cellular unit of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the nervous system.


stress-activated MAPK cascade

category: biolink:Pathway biolink:OntologyClass biolink:BiologicalProcess biolink:Occurrent biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: A MAPK cascade that starts with the activation of a stress-activated MAP kinase cascade.


name: glycerone phosphate:phosphate antiporter activity

description: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glycerone phosphate(out) + phosphate(in) = glycerone phosphate(in) + phosphate(out).


name: glyceraldehyde 3-phosphate:phosphate antiporter activity

description: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glyceraldehyde 3-phosphate(out) + phosphate(in) = glyceraldehyde 3-phosphate(in) + phosphate(out).


response to nitrosative stress

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrosative stress stimulus. Nitrosative stress is a state often resulting from exposure to high levels of nitric oxide (NO) or the highly reactive oxidant peroxynitrite, which is produced following interaction of NO with superoxide anions.


detoxification of nitrogen compound

description: Any process that reduces or removes the toxicity of nitrogenous compounds which are dangerous or toxic. This includes the aerobic conversion of toxic compounds to harmless substances.


response to corticosterone

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticosterone stimulus. Corticosterone is a 21 carbon steroid hormone of the corticosteroid type, produced in the cortex of the adrenal glands. In many species, corticosterone is the principal glucocorticoid, involved in regulation of fuel metabolism, immune reactions, and stress responses.


response to cortisone

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cortisone stimulus. Cortisone is a natural glucocorticoid steroid hormone that is metabolically convertible to cortisol. Cortisone is synthesized from cholesterol in the cortex of the adrenal gland under the stimulation of adrenocorticotropin hormone (ACTH). The main physiological effect of cortisone is on carbohydrate metabolism; it can stimulate increased glucose release from the liver, increased liver glycogen synthesis, and decreased utilization of glucose by the tissues.


response to cortisol

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cortisol stimulus. Cortisol is the major natural glucocorticoid synthesized in the zona fasciculata of the adrenal cortex; it affects the metabolism of glucose, protein, and fats and has appreciable mineralocorticoid activity. It also regulates the immune system and affects many other functions.


name: microtubule nucleation by interphase microtubule organizing center

description: The 'de novo' formation of a microtubule by the interphase microtubule organizing center during interphase, the stage of cell cycle between successive rounds of chromosome segregation.


name: microtubule nucleation by spindle pole body

description: The 'de novo' formation of a microtubule, mediated by the spindle pole body.


name: microtubule nucleation by microtubule organizing center

description: The 'de novo' formation of a microtubule, mediated by the microtubule organizing center.


corticotropin-releasing hormone binding

description: Binding to corticotropin-releasing hormone, a polypeptide hormone involved in the stress response. It is released by the hypothalamus and stimulates the release of corticotropin by the anterior pituitary gland.


PTB domain binding

description: Binding to a phosphotyrosine-binding (PTB) Binding to a phosphotyrosine-bindin domain.


hormone receptor binding

description: Binding to a receptor for a hormone.


peptide hormone receptor binding

description: Binding to a receptor for a peptide hormone.


name: corticotropin-releasing hormone receptor binding

description: Binding to a receptor for corticotropin-releasing hormone (CRH), a polypeptide hormone involved in the stress response. It is released by the hypothalamus and stimulates the release of corticotropin by the anterior pituitary gland.


name: corticotropin-releasing hormone receptor 1 binding

description: Binding to a corticotropin-releasing hormone receptor 1 (CRHR1). CRHR1 is the major subtype in the pituitary corticotroph, and mediates the stimulatory actions of corticotropin-releasing hormone on corticotropin hormone secretion. CRHR1 are also located in cortical areas of the brain, cerebellum and limbic system.


name: corticotropin-releasing hormone receptor 2 binding

description: Binding to a corticotropin-releasing hormone receptor type 2 (CRHR2). The CRHR2 has several splice variants that are located in sub-cortical areas of the brain and in the periphery.


BH1 domain binding

description: Binding to a BH1 protein domain, present in Bcl-2 family members. Proteins that act as inhibitors of apoptosis harbour at least three BH domains: BH1, BH2 and BH3; the BH1 and BH2 domains are found in all death antagonists of the Bcl-2 family but only in one class of death agonists.


BH2 domain binding

description: Binding to a BH2 protein domain, present in Bcl-2 family members. Proteins that act as inhibitors of apoptosis harbour at least three BH domains: BH1, BH2 and BH3; the BH1 and BH2 domains are found in all death antagonists of the Bcl-2 family but only in one class of death agonists.


BH3 domain binding

description: Binding to a BH3 protein domain, present in Bcl-2 family members. The BH3 domain is a potent death domain and has an important role in protein-protein interactions and in cell death.


BH4 domain binding

description: Binding to a BH4 protein domain, present in Bcl-2 family members. All anti-apoptotic proteins contain BH1 and BH2 domains; some also contain an additional N-terminal BH4 domain, which is almost never seen in pro-apoptotic proteins. Loss of the BH4 domain can diminish or abrogate anti-apoptotic function or even impart outright death-promoting properties to the protein.


name: regulation of ubiquitin-protein transferase activity

description: Any process that modulates the frequency, rate or extent of ubiquitin transferase activity.


name: positive regulation of ubiquitin-protein transferase activity

description: Any process that activates, maintains or increases the rate of ubiquitin transferase activity.


name: negative regulation of ubiquitin-protein transferase activity

description: Any process that stops, prevents, or reduces the frequency, rate or extent of ubiquitin transferase activity.


regulation of meiotic cell cycle

description: Any process that modulates the rate or extent of progression through the meiotic cell cycle.


name: positive regulation of meiotic cell cycle

description: Any process that activates or increases the frequency, rate or extent of progression through the meiotic cell cycle.


name: negative regulation of meiotic cell cycle

description: Any process that stops, prevents or reduces the rate or extent of progression through the meiotic cell cycle.


gonadotropin-releasing hormone binding

description: Binding to gonadotropin-releasing hormone (GnRH), a peptide hormone responsible for the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the anterior pituitary. GnRH is synthesized and released by the hypothalamus.


thyrotropin-releasing hormone binding

description: Binding to thyrotropin-releasing hormone, a tripeptide hormone that stimulates the release of thyroid-stimulating hormone (TSH) and prolactin by the anterior pituitary and it is produced by the hypothalamus and travels across the median eminence to the pituitary via the pituitary portal system.


myoblast proliferation

description: The multiplication or reproduction of myoblasts, resulting in the expansion of a myoblast cell population. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.


myoblast migration

description: The orderly movement of a myoblast from one site to another, often during the development of a multicellular organism. A myoblast is a cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.


intracellular pH reduction

description: Any process that reduces the internal pH of a cell, measured by the concentration of the hydrogen ion.


regulation of intracellular pH

description: Any process that modulates the internal pH of a cell, measured by the concentration of the hydrogen ion.


intracellular pH elevation

description: Any process that increases the internal pH of a cell, measured by the concentration of the hydrogen ion.


name: spindle attachment to meiosis I kinetochore

description: The cellular process in which spindle microtubules become physically associated with the proteins making up the kinetochore complex in meiosis I. During meiosis I sister kinetochores are lying next to each other facing the same spindle pole and monopolar attachment of the chromatid to the spindle occurs.


name: attachment of meiotic spindle microtubules to meiosis II kinetochore

description: The cellular process in which spindle microtubules become physically associated with the proteins making up the kinetochore complex in meiosis II. During meiosis II sister kinetochores are situated facing opposite spindle poles and bipolar attachment of the sister chromosomes to the spindle occurs.


name: maintenance of protein location in nucleus

description: Any process in which a protein is maintained in the nucleus and prevented from moving elsewhere. These include sequestration within the nucleus, protein stabilization to prevent transport elsewhere and the active retrieval of proteins that escape the nucleus.


corticotropin secretion

description: The regulated release of corticotropin by a cell. Corticotropin hormone is a polypeptide hormone synthesized and secreted from corticotropes in the anterior lobe of the pituitary gland in response to corticotropin-releasing hormone (CRH) released by the hypothalamus.


regulation of corticotropin secretion

description: Any process that modulates the frequency, rate or extent of the regulated release of corticotropic hormone from a cell.


name: negative regulation of corticotropin secretion

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of corticotropic hormone from a cell.


name: positive regulation of corticotropin secretion

description: Any process that activates or increases the frequency, rate or extent of the regulated release of corticotropin hormone from a cell.


regulation of cortisol secretion

description: Any process that modulates the frequency, rate or extent of the regulated release of cortisol from a cell.


name: negative regulation of cortisol secretion

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of cortisol from a cell.


name: positive regulation of cortisol secretion

description: Any process that activates or increases the frequency, rate or extent of the regulated release of cortisol from a cell.


name: negative regulation of corticotropin-releasing hormone secretion

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of corticotropin-releasing hormone from a cell.


name: positive regulation of corticotropin-releasing hormone secretion

description: Any process that activates or increases the frequency, rate or extent of the regulated release of corticotropin-releasing hormone from a cell.


detection of steroid hormone stimulus

description: The series of events by which a steroid hormone stimulus is received by a cell and converted into a molecular signal.


name: detection of glucocorticoid hormone stimulus

description: The series of events by which a glucocorticoid hormone stimulus is received by a cell and converted into a molecular signal. Glucocorticoids are hormonal C21 corticosteroids synthesized from cholesterol with the ability to bind with the cortisol receptor and trigger similar effects. Glucocorticoids act primarily on carbohydrate and protein metabolism, and have anti-inflammatory effects.


vesicle fusion with vacuole

description: The joining of the lipid bilayer membrane around a vesicle with the lipid bilayer membrane around the vacuole.


ectoine transmembrane transport

description: The directed movement of ectoine across a membrane by means of some agent such as a transporter or a pore. Ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidinecarboxylic acid) is a tetrahydropyrimidine commonly synthesized by halophilic bacteria.


glucosylglycerol metabolic process

description: The chemical reactions and pathways involving glucosylglycerol, alpha-D-glucopyranosyl-alpha-(1,2)-glycerol.


glucosylglycerol biosynthetic process

description: The chemical reactions and pathways resulting in the formation of glucosylglycerol, alpha-D-glucopyranosyl-alpha-(1,2)-glycerol.


name: glucosylglycerol transmembrane transporter activity

description: Enables the transfer of a glucosylglycerol from one side of a membrane to the other. A glucosylglycerol is an alpha-D-glucopyranosyl-alpha-(1,2)-glycerol.


description: The directed movement of glucosylglycerol, alpha-D-glucopyranosyl-alpha-(1,2)-glycerol, across a membrane.


name: phosphoenolpyruvate-dependent mannosylglycerate phosphotransferase system

description: A phosphoenolpyruvate-dependent sugar phosphotransferase transport specific for mammosylglycerate.


name: mannosylglycerate transmembrane transporter activity

description: Enables the transfer of a mannosylglycerate from one side of a membrane to the other.


mannosylglycerate metabolic process

description: The chemical reactions and pathways involving mannosylglycerate, a very common compatible solute in thermophilic and hyperthermophilic organisms.


mannosylglycerate biosynthetic process

description: The chemical reactions and pathways resulting in the formation of mannosylglycerate, a very common compatible solute in thermophilic and hyperthermophilic organisms.


name: regulation of cytosolic calcium ion concentration

description: Any process involved in the maintenance of an internal steady state of calcium ions within the cytosol of a cell or between the cytosol and its surroundings.


name: negative regulation of cytosolic calcium ion concentration

description: Any process that decreases the concentration of calcium ions in the cytosol.


name: terpenoid biosynthetic process, mevalonate-independent

description: The chemical reactions and pathways resulting in the formation of terpenoids, independent of mevalonate. Isopentenyl diphosphate (IPP) is the fundamental unit in terpenoid biosynthesis, and in mevalonate-independent biosynthesis, it is produced from pyruvate and glyceraldehyde 3-phosphate via intermediates including 1-deoxy-D-xylulose 5-phosphate.


name: isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway involved in terpenoid biosynthetic process

description: The chemical reactions and pathways resulting in the formation of isopentenyl diphosphate by the mevalonate-independent pathway that contributes to terpenoid biosynthesis. Isopentenyl diphosphate (IPP) is the fundamental unit in isoprenoid biosynthesis and is biosynthesized from pyruvate and glyceraldehyde 3-phosphate via intermediates, including 1-deoxy-D-xylulose 5-phosphate.


name: terpenoid biosynthetic process, mevalonate-dependent

description: The chemical reactions and pathways resulting in the formation of terpenoids via isopentenyl diphosphate, synthesized by the mevalonate pathway. Isopentenyl diphosphate (IPP) is the fundamental unit in terpenoid biosynthesis, and in mevalonate-dependent terpenoid biosynthesis, acetate, in the form of acetyl-CoA, is converted to isopentenyl diphosphate (IPP) through a series of mevalonate intermediates.


name: isopentenyl diphosphate biosynthetic process, mevalonate pathway involved in terpenoid biosynthetic process

description: The chemical reactions and pathways resulting in the formation of isopentenyl diphosphate by the mevalonate pathway that contributes to terpenoid biosynthesis. This pathway converts acetate, in the form of acetyl-CoA, to isopentenyl diphosphate (IPP) through a series of mevalonate intermediates.


regulation of filopodium assembly

description: Any process that modulates the frequency, rate or extent of the assembly of a filopodium, a thin, stiff protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal growth cone.


name: negative regulation of filopodium assembly

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the assembly of a filopodium, a thin, stiff protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal growth cone.


name: positive regulation of filopodium assembly

description: Any process that activates or increases the frequency, rate or extent of the assembly of a filopodium, a thin, stiff protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal growth cone.


regulation of stress fiber assembly

description: Any process that modulates the frequency, rate or extent of the assembly of a stress fiber, a bundle of microfilaments and other proteins found in fibroblasts.


regulation of cytoskeleton organization

description: Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures.


name: negative regulation of cytoskeleton organization

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures.


name: positive regulation of cytoskeleton organization

description: Any process that activates or increases the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures.


name: positive regulation of stress fiber assembly

description: Any process that activates or increases the frequency, rate or extent of the assembly of a stress fiber, a bundle of microfilaments and other proteins found in fibroblasts.


name: negative regulation of stress fiber assembly

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the assembly a stress fiber, a bundle of microfilaments and other proteins found in fibroblasts.


name: syn-copalyl diphosphate synthase activity

description: Catalysis of the reaction: geranylgeranyl diphosphate = 9alpha-copalyl diphosphate.


D-aminoacyl-tRNA deacylase activity

description: Catalysis of the reaction: D-aminoacyl-tRNA = D-amino acid + tRNA. Hydrolysis of the removal of D-amino acids from residues in charged tRNA.


D-tyrosyl-tRNA(Tyr) deacylase activity

description: Catalysis of the reaction: D-tyrosyl-tRNA(Tyr) = D-tyrosine + tRNA(Tyr). Hydrolysis of the removal of D-tyrosine from tyrosine residues in charged tRNA.


diterpene phytoalexin metabolic process

description: The chemical reactions and pathways involving diterpene phytoalexins, a class of diterpene formed in plants in response to fungal infection, physical damage, chemical injury, or a pathogenic process; they are sometimes referred to as plant antibiotics. Diterpenes are unsaturated hydrocarbons containing 20 carbon atoms and 4 branched methyl groups and are made up of isoprenoid units.


name: diterpene phytoalexin biosynthetic process

description: The chemical reactions and pathways resulting in the formation of diterpene phytoalexins, terpenoids with 20 carbons produced by plants in response to environmental stresses.


adenine nucleotide transport

description: The directed movement of adenine nucleotides, ATP, ADP, and/or AMP, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


name: diterpene phytoalexin precursor biosynthetic process pathway

description: A branched pathway that produces the precursors to four structurally distinct types of polycyclic diterpenes. The pathway starts with the cyclization of geranylgeranyl diphosphate into ent-copalyl diphosphate and syn-copalyl diphosphate. The catalytic conversion by diterpene cyclases of these two compounds produces the four diterpene hydrocarbons which are precursors to the four structurally distinct classes of diterpene phytoalexins.


name: regulation of unidimensional cell growth

description: Any process that modulates the frequency, rate or extent of unidimensional cell growth, the process in which a cell irreversibly increases in size in one [spatial] dimension or along one axis.


name: negative regulation of unidimensional cell growth

description: Any process that stops, prevents, or reduces the frequency, rate or extent of unidimensional cell growth, the process in which a cell irreversibly increases in size in one [spatial] dimension or along one axis.


name: positive regulation of unidimensional cell growth

description: Any process that activates or increases the frequency, rate or extent of unidimensional cell growth, the process in which a cell irreversibly increases in size in one [spatial] dimension or along one axis.


regulation of monopolar cell growth

description: Any process that modulates the frequency, rate or extent of monopolar cell growth, polarized growth from one end of a cell.


name: negative regulation of monopolar cell growth

description: Any process that stops, prevents, or reduces the frequency, rate or extent of monopolar cell growth, polarized growth from one end of a cell.


name: positive regulation of monopolar cell growth

description: Any process that activates or increases the frequency, rate or extent of monopolar cell growth, polarized growth from one end of a cell.


regulation of bipolar cell growth

description: Any process that modulates the frequency, rate or extent of bipolar cell growth, polarized growth from both ends of a cell.


name: negative regulation of bipolar cell growth

description: Any process that stops, prevents, or reduces the frequency, rate or extent of bipolar cell growth, polarized growth from both ends of a cell.


name: positive regulation of bipolar cell growth

description: Any process that activates or increases the frequency, rate or extent of bipolar cell growth, polarized growth from both ends of a cell.


activation of bipolar cell growth

description: Any process that initiates the inactive process of bipolar cell growth, polarized growth from both ends of a cell.


termination of bipolar cell growth

description: Any process that stops the active process of bipolar cell growth, polarized growth from both ends of a cell.


termination of monopolar cell growth

description: Any process that stops the active process of bipolar cell growth, polarized growth from one end of a cell.


activation of monopolar cell growth

description: Any process that initiates the inactive process of monopolar cell growth, polarized growth from one end of a cell.


name: cell growth mode switching, monopolar to bipolar

description: The process in which a cell switches from monopolar cell growth to bipolar cell growth.


name: cell growth mode switching, bipolar to monopolar

description: The process in which a cell switches from bipolar cell growth to monopolar cell growth.


NFAT protein binding

description: Binding to NFAT (nuclear factor of activated T cells) proteins, a family of transcription factors. NFAT proteins have crucial roles in the development and function of the immune system.


iron-sulfur cluster binding

description: Binding to an iron-sulfur cluster, a combination of iron and sulfur atoms.


2 iron, 2 sulfur cluster binding

description: Binding to a 2 iron, 2 sulfur (2Fe-2S) cluster; this cluster consists of two iron atoms, with two inorganic sulfur atoms found between the irons and acting as bridging ligands.


3 iron, 4 sulfur cluster binding

description: Binding to a 3 iron, 4 sulfur (3Fe-4S) cluster; this cluster consists of three iron atoms, with the inorganic sulfur atoms found between the irons and acting as bridging ligands. It is essentially a 4Fe-4S cluster with one iron missing.


4 iron, 4 sulfur cluster binding

description: Binding to a 4 iron, 4 sulfur (4Fe-4S) cluster; this cluster consists of four iron atoms, with the inorganic sulfur atoms found between the irons and acting as bridging ligands.


metal cluster binding

description: Binding to a cluster of atoms including both metal ions and nonmetal atoms, usually sulfur and oxygen. Examples include iron-sulfur clusters and nickel-iron-sulfur clusters.


elastin metabolic process

description: The chemical reactions and pathways involving elastin, a glycoprotein which is randomly coiled and crosslinked to form elastic fibers that are found in connective tissue.


elastin biosynthetic process

description: The chemical reactions and pathways resulting in the formation of elastin, a fibrous glycoprotein found in elastic tissues such as the walls of arteries.


name: regulation of elastin biosynthetic process

description: Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of elastin.


name: positive regulation of elastin biosynthetic process

description: Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of elastin.


name: negative regulation of elastin biosynthetic process

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of elastin.


keratinocyte migration

description: The directed movement of a keratinocyte, epidermal cells which synthesize keratin, from one site to another.


regulation of keratinocyte migration

description: Any process that modulates the frequency, rate or extent of keratinocyte migration.


name: negative regulation of keratinocyte migration

description: Any process that stops, prevents, or reduces the frequency, rate or extent of keratinocyte migration.


name: positive regulation of keratinocyte migration

description: Any process that activates or increases the frequency, rate or extent of keratinocyte migration.


aurone metabolic process

description: The chemical reactions and pathways involving aurones, a series of plant flavonoids that provide a yellow colour to flowers. They have the basic skeletal structure of two benzene rings joined by a linear C3 chain (C6-C3-C6). Aurones exist mostly as 6-O-glucosides.


aurone biosynthetic process

description: The chemical reactions and pathways resulting in the formation of aurones, a series of yellow plant pigments.


flavone metabolic process

description: The chemical reactions and pathways involving flavones, a class of pigmented plant compounds based on 2-phenyl-4H-1-benzopyran-4-one (2-phenylchromone).


flavone biosynthetic process

description: The chemical reactions and pathways resulting in the formation of flavones, a class of pigmented plant compounds based on 2-phenyl-4H-1-benzopyran-4-one (2-phenylchromone).


flavonol metabolic process

description: The chemical reactions and pathways involving flavonols, a member of a class of vascular pigments formed by consecutive oxidative processes from the flavonoid intermediates flavanones and dihydroflavonols. Flavonols are the most widespread of the flavonoids and have a wide array of physiological activities.


flavonol biosynthetic process

description: The chemical reactions and pathways resulting in the formation of flavonols, a member of a class of vascular pigments formed by consecutive oxidative processes from the flavonoid intermediates flavanones and dihydroflavonols. Flavonols are the most widespread of the flavonoids and have a wide array of physiological activities.


leucoanthocyanidin metabolic process

description: The chemical reactions and pathways involving leucoanthocyanidins, a class of colorless intermediates in the biosynthetic pathway of the pigmented flavonoids.


leucoanthocyanidin biosynthetic process

description: The chemical reactions and pathways resulting in the formation of leucoanthocyanidins, a class of colorless intermediates in the biosynthetic pathway of the pigmented flavonoids.


phlobaphene metabolic process

description: The chemical reactions and pathways involving phlobaphenes, red pigments with oligomeric or polymeric structure derived from the flavonoid intermediate flavan-4-ols.


phlobaphene biosynthetic process

description: The chemical reactions and pathways resulting in the formation of phlobaphenes, red pigments with oligomeric or polymeric structure derived from the flavonoid intermediate flavan-4-ols.


mitochondrial calcium ion homeostasis

description: Any process involved in the maintenance of an internal steady state of calcium ions within the cytoplasm of a cell or between mitochondria and their surroundings.


name: positive regulation of mitochondrial calcium ion concentration

description: Any process that increases the concentration of calcium ions in mitochondria.


name: negative regulation of mitochondrial calcium ion concentration

description: Any process that decreases the concentration of calcium ions in mitochondria.


name: smooth endoplasmic reticulum calcium ion homeostasis

description: Any process involved in the maintenance of an internal steady state of calcium ions within the smooth endoplasmic reticulum of a cell or between the smooth endoplasmic reticulum and its surroundings.


name: positive regulation of smooth endoplasmic reticulum calcium ion concentration

description: Any process that increases the concentration of calcium ions in the smooth endoplasmic reticulum.


name: negative regulation of smooth endoplasmic reticulum calcium ion concentration

description: Any process that decreases the concentration of calcium ions in the smooth endoplasmic reticulum.


description: Catalysis of the reaction: anthocyanidin 3-glucoside + UDP-rhamnose = anthocyanidin 3-rutinoside + UDP.


description: Catalysis of the beta-elimination of the 5' deoxyribose-5-phosphate at an abasic site in DNA where a DNA-(apurinic or apyrimidinic site) lyase has already cleaved the C-O-P bond 3' to the apurinic or apyrimidinic site.


regulation of neurotransmitter uptake

description: Any process that modulates the frequency, rate or extent of the directed movement of a neurotransmitter into a neuron or glial cell.


name: negative regulation of neurotransmitter uptake

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a neurotransmitter into a neuron or glial cell.


name: positive regulation of neurotransmitter uptake

description: Any process that activates or increases the frequency, rate or extent of the directed movement of a neurotransmitter into a neuron or glial cell.


name: dopamine uptake involved in synaptic transmission

description: The directed movement of dopamine into a presynaptic neuron or glial cell. In this context, dopamine is a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline.


name: regulation of dopamine uptake involved in synaptic transmission

description: Any process that modulates the frequency, rate or extent of the directed movement of the catecholamine neurotransmitter dopamine into a cell.


name: negative regulation of dopamine uptake involved in synaptic transmission

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of dopamine into a presynaptic neuron or glial cell.


name: positive regulation of dopamine uptake involved in synaptic transmission

description: Any process that activates or increases the frequency, rate or extent of the directed movement of dopamine into a cell.


name: inhibition of dopamine uptake involved in synaptic transmission

description: Any process that prevents the activation of the directed movement of dopamine into a cell.


name: regulation of neurotransmitter transport

description: Any process that modulates the frequency, rate or extent of the directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


name: negative regulation of neurotransmitter transport

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


name: positive regulation of neurotransmitter transport

description: Any process that activates or increases the frequency, rate or extent of the directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


response to cAMP

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate) stimulus.


response to calcium ion

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus.


response to folic acid

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a folic acid stimulus.


detection of glucose

description: The series of events in which a glucose stimulus is received by a cell and converted into a molecular signal.


response to methylglyoxal

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylglyoxal stimulus. Methylglyoxal is a 2-oxoaldehyde derived from propanal.


methylglyoxal catabolic process

description: The chemical reactions and pathways resulting in the breakdown of methylglyoxal, CH3-CO-CHO, the aldehyde of pyruvic acid.


response to methylmercury

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylmercury stimulus.


name: meiotic recombination checkpoint signaling

description: A signaling process that contributes to a meiotic recombination checkpoint, that acts during late prophase I (pachytene) and prevents segregation of homologous chromosomes until recombination is completed, ensuring proper distribution of the genetic material to the gametes.


response to hydrostatic pressure

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrostatic pressure stimulus. Hydrostatic pressure is the force acting on an object in a system where the fluid is at rest (as opposed to moving). The weight of the fluid above the object creates pressure on it.


name: regulation of endocytosis by exocyst localization

description: Any process in which an exocyst is transported to, or maintained in, a specific location that results in the modulation of endocytosis. An exocyst is a protein complex peripherally associated with the plasma membrane that determines where vesicles dock and fuse.


exocyst localization

description: Any process in which an exocyst is transported to, or maintained in, a specific location. An exocyst is a protein complex peripherally associated with the plasma membrane that determines where vesicles dock and fuse.


response to electrical stimulus

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electrical stimulus.


name: proteolysis involved in protein catabolic process

description: The hydrolysis of a peptide bond or bonds within a protein as part of the chemical reactions and pathways resulting in the breakdown of a protein by individual cells.


protein maturation

description: Any process leading to the attainment of the full functional capacity of a protein.


detection of stimulus

description: The series of events in which a stimulus is received by a cell or organism and converted into a molecular signal.


defense response to virus

description: Reactions triggered in response to the presence of a virus that act to protect the cell or organism.


histamine transport

description: The directed movement of histamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Histamine is a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans.


inhibition of neurotransmitter uptake

description: Any process that prevents the activation of the directed movement of a neurotransmitter into a cell.


serotonin uptake

description: The directed movement of serotonin into a cell, typically presynaptic neurons or glial cells. Serotonin (5-hydroxytryptamine) is a monoamine neurotransmitter occurring in the peripheral and central nervous systems.


regulation of serotonin uptake

description: Any process that modulates the frequency, rate or extent of the directed movement of the monoamine neurotransmitter serotonin into a cell.


negative regulation of serotonin uptake

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of serotonin into a cell.


positive regulation of serotonin uptake

description: Any process that activates or increases the frequency, rate or extent of the directed movement of serotonin into a cell.


inhibition of serotonin uptake

description: Any process that prevents the activation of the directed movement of serotonin into a cell.


histamine uptake

description: The directed movement of histamine into a cell, typically presynaptic neurons or glial cells. Histamine is a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans.


regulation of histamine uptake

description: Any process that modulates the frequency, rate or extent of the directed movement of the neurotransmitter histamine into a cell.


negative regulation of histamine uptake

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of histamine into a cell.


positive regulation of histamine uptake

description: Any process that activates or increases the frequency, rate or extent of the directed movement of histamine into a cell.


inhibition of histamine uptake

description: Any process that prevents the activation of the directed movement of histamine into a cell.


norepinephrine uptake

description: The directed movement of norepinephrine into a cell, typically presynaptic neurons or glial cells. Norepinephrine (3,4-dihydroxyphenyl-2-aminoethanol) is a hormone secreted by the adrenal medulla and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts of the CNS. It is also the biosynthetic precursor of epinephrine.


regulation of norepinephrine uptake

description: Any process that modulates the frequency, rate or extent of the directed movement of the neurotransmitter norepinephrine into a cell.


name: negative regulation of norepinephrine uptake

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of norepinephrine into a cell.


name: positive regulation of norepinephrine uptake

description: Any process that activates or increases the frequency, rate or extent of the directed movement of norepinephrine into a cell.


inhibition of norepinephrine uptake

description: Any process that prevents the activation of the directed movement of norepinephrine into a cell.


epinephrine uptake

description: The directed movement of epinephrine into a cell, typically presynaptic neurons or glial cells. Epinephrine is a hormone produced by the medulla of the adrenal glands that increases heart activity, improves the power and prolongs the action of muscles, and increases the rate and depth of breathing. It is synthesized by the methylation of norepinephrine.


regulation of epinephrine uptake

description: Any process that modulates the frequency, rate or extent of the directed movement of the neurotransmitter epinephrine into a cell.


name: negative regulation of epinephrine uptake

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of epinephrine into a cell.


name: positive regulation of epinephrine uptake

description: Any process that activates or increases the frequency, rate or extent of the directed movement of epinephrine into a cell.


inhibition of epinephrine uptake

description: Any process that prevents the activation of the directed movement of epinephrine into a cell.


acetylcholine uptake

description: The directed movement of acetylcholine into a cell, typically presynaptic neurons or glial cells. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues.


regulation of acetylcholine uptake

description: Any process that modulates the frequency, rate or extent of the directed movement of the neurotransmitter acetylcholine into a cell.


name: negative regulation of acetylcholine uptake

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of acetylcholine into a cell.


name: positive regulation of acetylcholine uptake

description: Any process that activates or increases the frequency, rate or extent of the directed movement of acetylcholine into a cell.


inhibition of acetylcholine uptake

description: Any process that prevents the activation of the directed movement of acetylcholine into a cell.


barbed-end actin filament uncapping

description: The removal of capping protein from the barbed (or plus) end of actin filaments to free the ends for addition, exchange or removal of further actin subunits.


actin filament network formation

description: The assembly of a network of actin filaments; actin filaments on different axes and with differing orientations are crosslinked together to form a mesh of filaments.


organelle localization

description: Any process in which an organelle is transported to, and/or maintained in, a specific location.


cellular localization

description: A cellular localization process whereby a substance or cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in, a specific location within a cell including the localization of substances or cellular entities to the cell membrane.


centrosome localization

description: Any process in which a centrosome is transported to, and/or maintained in, a specific location within the cell.


endoplasmic reticulum localization

description: Any process in which endoplasmic reticulum is transported to, and/or maintained in, a specific location within the cell.


plastid localization

description: Any process in which a plastid is transported to, and/or maintained in, a specific location within the cell.


Golgi localization

description: Any process in which the Golgi is transported to, and/or maintained in, a specific location within the cell.


mitochondrion localization

description: Any process in which a mitochondrion or mitochondria are transported to, and/or maintained in, a specific location within the cell.


nucleus localization

description: Any process in which the nucleus is transported to, and/or maintained in, a specific location within the cell.


vesicle localization

description: Any process in which a vesicle or vesicles are transported to, and/or maintained in, a specific location.


establishment of localization in cell

description: Any process, occurring in a cell, that localizes a substance or cellular component. This may occur via movement, tethering or selective degradation.


establishment of vesicle localization

description: The directed movement of a vesicle to a specific location.


maintenance of location in cell

description: Any process in which a substance or cellular entity, such as a protein complex or organelle, is maintained in a specific location within, or in the membrane of, a cell, and is prevented from moving elsewhere.


maintenance of chromosome location

description: Any process in which a chromosome is maintained in a specific location within a cell and prevented from moving elsewhere.


spindle localization

description: Any process in which is the spindle is transported to, and/or maintained in, a specific location.


name: establishment of mitochondrion localization

description: The directed movement of the mitochondrion to a specific location.


maintenance of vesicle location

description: Any process in which a vesicle is maintained in a specific location within a cell and prevented from moving elsewhere.


establishment of organelle localization

description: The directed movement of an organelle to a specific location.


maintenance of organelle location

description: Any process in which an organelle is maintained in a specific location within a cell and prevented from moving elsewhere.


maintenance of nucleus location

description: Any process in which the nucleus is maintained in a specific location within a cell and prevented from moving elsewhere.


maintenance of mitochondrion location

description: Any process in which a mitochondrion is maintained in a specific location within a cell and prevented from moving elsewhere.


name: establishment of centrosome localization

description: The directed movement of the centrosome to a specific location.


maintenance of centrosome location

description: Any process in which a centrosome is maintained in a specific location within a cell and prevented from moving elsewhere.


name: oocyte nucleus localization involved in oocyte dorsal/ventral axis specification

description: The directed movement of the nucleus to a specific location within a cell during the establishment and maintenance of the dorsal/ventral axis of the oocyte.


nuclear pore localization

description: Any process in which nuclear pores are transported to, or maintained in, a specific location.


membrane raft localization

description: Any process in which membrane rafts are transported to, or maintained in, a specific location. Membrane rafts are small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes.


actin cortical patch localization

description: Any process in which actin cortical patches are transported to, or maintained in, a specific location. An actin cortical patch is a discrete actin-containing structure found just beneath the plasma membrane in fungal cells.


establishment of plastid localization

description: The directed movement of a plastid to a specific location in the cell.


localization within membrane

description: Any process in which a substance or cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in, a specific location within a membrane.


fructan beta-fructosidase activity

description: Catalysis of the hydrolysis of terminal, non-reducing 2,1- and 2,6-linked beta-D-fructofuranose residues in fructans.


inulinase activity

description: Catalysis of the endohydrolysis of 2,1-beta-D-fructosidic linkages in inulin.


name: disruption of plasma membrane integrity in another organism

description: The disruption of the cell membrane of another organism, leading to damage or temporary subversion of the membrane.


localization of cell

description: Any process in which a cell is transported to, and/or maintained in, a specific location.


isopullulanase activity

description: Catalysis of the hydrolysis of pullulan to isopanose (6-alpha-maltosylglucose).


pullulan metabolic process

description: The chemical reactions and pathways involving pullulan, a neutral linear polysaccharide composed of repeating units of maltotriose joined by alpha-(1,6)-linkages.


pullulan biosynthetic process

description: The chemical reactions and pathways resulting in the formation of pullulan, a neutral linear polysaccharide composed of repeating units of maltotriose joined by alpha-(1,6)-linkages.


pullulan catabolic process

description: The chemical reactions and pathways resulting in the breakdown of pullulan, a neutral linear polysaccharide composed of repeating units of maltotriose joined by alpha-(1,6)-linkages.


description: The chemical reactions and pathways involving 6-alpha-maltosylglucose, also known as isopanose.


description: The chemical reactions and pathways resulting in the formation of 6-alpha-maltosylglucose, also known as isopanose.


description: The chemical reactions and pathways resulting in the breakdown of 6-alpha-maltosylglucose, also known as isopanose.


galactomannan catabolic process

description: The chemical reactions and pathways resulting in the breakdown of galactomannan, a polysaccharide composed of D-galactosyl and D-mannosyl. The mannosyl units form the backbone structure (a linear main chain) with the D-galactosyl as single side units.


establishment of Golgi localization

description: The directed movement of the Golgi to a specific location.


maintenance of Golgi location

description: Any process in which the Golgi is maintained in a specific location within a cell and prevented from moving elsewhere.


maintenance of ER location

description: Any process in which the endoplasmic reticulum is maintained in a specific location within a cell and prevented from moving elsewhere.


establishment of ER localization

description: The directed movement of the endoplasmic reticulum to a specific location.


maintenance of spindle location

description: Any process in which the spindle is maintained in a specific location within a cell and prevented from moving elsewhere.


maintenance of plastid location

description: Any process in which a plastid is maintained in a specific location within a cell and prevented from moving elsewhere.


actin filament capping

description: The binding of a protein or protein complex to the end of an actin filament, thus preventing the addition, exchange or removal of further actin subunits.


pointed-end actin filament capping

description: The binding of a protein or protein complex to the pointed (or minus) end of an actin filament, thus preventing the addition, exchange or removal of further actin subunits.


actin filament uncapping

description: The removal of capping protein from the end of actin filaments to free the ends for addition, exchange or removal of further actin subunits.


pointed-end actin filament uncapping

description: The removal of capping protein from the pointed (or minus) end of actin filaments to free the ends for addition, exchange or removal of further actin subunits.


protein delipidation

description: The breakage of covalent bonds to detach lipid groups from a protein.


saccharopine oxidase activity

description: Catalysis of the reaction: L-saccharopine + O2 = L-2-aminoadipic 6-semialdehyde + L-glutamate + H2O2.


fructosyl-amino acid oxidase activity

description: Catalysis of the reaction: fructosyl-amino acid + O2 = corresponding amino acid + glucosone + H2O2.


name: biological process involved in interaction with host

description: An interaction between two organisms living together in more or less intimate association. The term host is used for the larger (macro) of the two members of a symbiosis; the various forms of symbiosis include parasitism, commensalism and mutualism.


name: biological process involved in interaction with symbiont

description: An interaction between two organisms living together in more or less intimate association. The term symbiont is used for the smaller (macro) of the two members of a symbiosis; the various forms of symbiosis include parasitism, commensalism and mutualism.


name: biological process involved in intraspecies interaction between organisms

description: Any process in which an organism has an effect on an organism of the same species.


response to other organism

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from another living organism.


name: regulation of killing of cells of another organism

description: Any process that modulates the frequency, rate or extent of the killing by an organism of cells in another organism.


name: negative regulation of killing of cells of another organism

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the killing by an organism of cells in another organism.


name: positive regulation of killing of cells of another organism

description: Any process that activates or increases the frequency, rate or extent of the killing by an organism of cells in another organism.


cytolysis in another organism

description: The killing by an organism of a cell in another organism by means of the rupture of cell membranes and the loss of cytoplasm.


cellular response to stimulus

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus by a cell and ends with a change in state or activity or the cell.


description: Catalysis of the reaction: inositol-1,3,4,5-tetrakisphosphate + H2O = inositol-1,4,5-trisphosphate + phosphate.


name: DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates

description: Catalysis of the reaction: S-adenosyl-L-methionine + CpG (in DNA) = S-adenosyl-L-homocysteine + 5-MeCpG (in DNA).


name: DNA (cytosine-5-)-methyltransferase activity, acting on CpN substrates

description: Catalysis of the reaction: S-adenosyl-L-methionine + DNA containing CpN = S-adenosyl-L-homocysteine + DNA containing 5-MeCpN.


name: DNA (cytosine-5-)-methyltransferase activity, acting on CpNpG substrates

description: Catalysis of the reaction: S-adenosyl-L-methionine + DNA containing CpNpG = S-adenosyl-L-homocysteine + DNA containing 5-MeCpNpG.


protein phosphatase 2A binding

description: Binding to protein phosphatase 2A.


name: protein C-terminal methylesterase activity

description: Catalysis of the reaction: C-terminal protein amino acid methyl ester + H2O = protein amino acid + methanol.


protein methylesterase activity

description: Catalysis of the reaction: protein amino acid methyl ester + H2O = protein amino acid + methanol.


NAD transmembrane transporter activity

description: Enables the transfer of NAD from one side of a membrane to the other.


protein de-ADP-ribosylation

description: The process of removing one or more ADP-ribose residues from a protein.


regulation of cell cycle

description: Any process that modulates the rate or extent of progression through the cell cycle.


name: cell cycle switching, mitotic to meiotic cell cycle

description: The process in which a cell switches cell cycle mode from mitotic to meiotic division.


name: germline cell cycle switching, mitotic to meiotic cell cycle

description: The process in which a germline cell switches cell cycle mode from mitotic to meiotic division.


name: GTP-dependent polyribonucleotide 5'-hydroxyl-kinase activity

description: Catalysis of the reaction: GTP + 5'-dephospho-RNA = GDP + 5'-phospho-RNA.


description: Catalysis of the reaction: NTP + 5'-dephosphopolynucleotide = NDP + 5'-phosphopolynucleotide. The polynucleotide may be DNA or RNA.


name: ATP-dependent polynucleotide 5'-hydroxyl-kinase activity

description: Catalysis of the reaction: ATP + 5'-dephosphopolynucleotide = ADP + 5'-phosphopolynucleotide. The polynucleotide may be DNA or RNA.


name: GTP-dependent polynucleotide 5'-hydroxyl-kinase activity

description: Catalysis of the reaction: GTP + 5'-dephosphopolynucleotide = GDP + 5'-phosphopolynucleotide. The polynucleotide may be DNA or RNA.


name: ATP-dependent polyribonucleotide 5'-hydroxyl-kinase activity

description: Catalysis of the reaction: ATP + 5'-dephospho-RNA = ADP + 5'-phospho-RNA.


name: GTP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity

description: Catalysis of the reaction: GTP + 5'-dephospho-DNA = GDP + 5'-phospho-DNA.


xanthophyll binding

description: Binding to xanthophylls, any of several neutral yellow to orange carotenoid pigments containing oxygen.


ethylene binding

description: Binding to ethylene (C2-H4, ethene), a simple hydrocarbon gas that can function in plants as a growth regulator.


description: Catalysis of the reaction: 2-methyl-6-phytyl-1,4-benzoquinone + S-adenosyl-methionine = 2,3-dimethyl-6-phytyl-1,4-benzoquinone + S-adenosyl-homocysteine.


description: Catalysis of the reaction: 2-methyl-6-solanyl-1,4-benzoquinone + S-adenosyl-methionine = 2,3-dimethyl-6-solanyl-1,4-benzoquinone + S-adenosyl-homocysteine.


name: red chlorophyll catabolite reductase activity

description: Catalysis of the reaction: red chlorophyll catabolite + reduced ferredoxin + 2 H+ = primary fluorescent catabolite + oxidized ferredoxin. This reaction is the reduction of the C20/C1 double bond in the pyrrole system of red chlorophyll catabolite (RCC) to a colorless tetrapyrrole (pFCC) with a strong blue fluorescence.


name: 3,8-divinyl protochlorophyllide a 8-vinyl reductase activity

description: Catalysis of the reaction: divinyl protochlorophyllide a + NADPH + H+ = monovinyl protochlorophyllide a + NADP+.


name: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase activity

description: Catalyzes the conversion of (2E)-4-hydroxy-3-methylbut-2-enyl diphosphate + 2 H+ + 2 reduced [2Fe-2S]-[ferredoxin] to isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) releasing H2O + 2 oxidized [2Fe-2S]-[ferredoxin]. Note that (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate is an alternative name for 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.


thalianol synthase activity

description: Catalysis of the cyclization of 3(S)-oxidosqualene to (3S,13S,14R)-malabarica-8,17,21-trien-3-ol (thalianol).


cytosine C-5 DNA demethylase activity

description: Catalysis of the reaction: methyl-dCpdG DNA + H2O = dCpdG DNA + methanol. This reaction is the hydrolytic removal of the methyl group on the 5 position of cytosine in DNA.


description: Catalysis of the reaction: UTP + a monosaccharide 1-phosphate = diphosphate + UDP-monosaccharide.


name: indole acetic acid carboxyl methyltransferase activity

description: Catalysis of the reaction: indole acetic acid + S-adenosyl-methionine = methyl indole acetic acid ester + S-adenosyl-homocysteine.


description: Catalysis of the reaction: a (3E,5Z)-dienoyl-CoA = a (2E,4E)-(5,6-saturated)-dienoyl-CoA.


alpha-1,4-mannosyltransferase activity

description: Catalysis of the transfer of a mannose residue to an oligosaccharide, forming an alpha-(1->4) linkage.


phosphoglucan, water dikinase activity

description: Catalysis of the reaction: ATP + [phospho-alpha-glucan] + H2O = AMP + O-phospho-[phospho-alpha-glucan] + phosphate.


mannan synthase activity

description: Catalysis of the reaction: mannan(n) + GDP-mannose = mannan(n+1) + GDP. This reaction is the formation of the beta-(1->4)-linked mannan backbone in substrates such as galactomannan.


name: meiotic sister chromatid cohesion, centromeric

description: The cell cycle process in which centromeres of sister chromatids are joined during meiosis.


meiotic sister chromatid arm separation

description: The cell cycle process in which sister chromatid arms are physically detached from each other during meiosis.


name: meiotic sister chromatid centromere separation

description: The cell cycle process in which the centromeres of sister chromatids are physically detached from each other during meiosis.


meiotic sister chromatid separation

description: The process in which sister chromatids are physically detached from each other during meiosis.


name: homologous chromosome movement towards spindle pole in meiosis I anaphase

description: The directed movement of homologous chromosomes from the center of the spindle towards the spindle poles, mediated by the shortening of microtubules attached to the chromosomes, during meiosis I anaphase.


name: sister chromosome movement towards spindle pole involved in meiotic sister chromatid segregation

description: The directed movement of sister chromosomes from the center of the spindle towards the spindle poles, mediated by the shortening of microtubules attached to the chromosomes, during meiosis II.


sesquiterpene metabolic process

description: The chemical reactions and pathways involving sesquiterpenes, any of a class of terpenes of the formula C15H24 or a derivative of such a terpene.


sesquiterpene biosynthetic process

description: The chemical reactions and pathways resulting in the formation of sesquiterpenes, any of a class of terpenes of the formula C15H24 or a derivative of such a terpene.


sesquiterpene catabolic process

description: The chemical reactions and pathways resulting in the breakdown of sesquiterpenes, any of a class of terpenes of the formula C15H24 or a derivative of such a terpene.


actin crosslink formation

description: The process in which two or more actin filaments are connected together by proteins that act as crosslinks between the filaments. The crosslinked filaments may be on the same or differing axes.


name: inositol tetrakisphosphate kinase activity

description: Catalysis of the reaction: inositol tetrakisphosphate + ATP = inositol pentakisphosphate + ADP.


inositol trisphosphate kinase activity

description: Catalysis of the reaction: inositol trisphosphate + ATP = inositol tetrakisphosphate + ADP + H+.


name: nitric-oxide synthase biosynthetic process

description: The chemical reactions and pathways resulting in the formation of a nitric-oxide synthase, an enzyme which catalyzes the reaction L-arginine + n NADPH + n H+ + m O2 = citrulline + nitric oxide + n NADP+.


name: regulation of nitric-oxide synthase biosynthetic process

description: Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of a nitric-oxide synthase enzyme.


name: positive regulation of nitric-oxide synthase biosynthetic process

description: Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of a nitric oxide synthase enzyme.


name: negative regulation of nitric-oxide synthase biosynthetic process

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of a nitric-oxide synthase enzyme.


response to redox state

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating redox state. Redox state refers to the balance of oxidized versus reduced forms of electron donors and acceptors in an organelle, cell or organ; plastoquinone, glutathione (GSH/GSSG), and nicotinamide nucleotides (NAD+/NADH and NADP+/NADPH) are among the most important.


detection of redox state

description: The series of events in which a chemical stimulus indicating redox state is received and converted into a molecular signal. Redox state refers to the balance of oxidized versus reduced forms of electron donors and acceptors in an organelle, cell or organ; plastoquinone, glutathione (GSH/GSSG), and nicotinamide nucleotides (NAD+/NADH and NADP+/NADPH) are among the most important.


name: ent-kaurenoic acid monooxygenase activity

description: Catalysis of the reaction:ent-kaur-16-en-19-oate + 3 O2 + 3 reduced [NADPH--hemoprotein reductase] = gibberellin A12 + 4 H+ + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase]. Catalyzes three successive oxidations of ent-kaurenoic acid.


behavioral response to nutrient

description: Any process that results in a change in the behavior of an organism as a result of a nutrient stimulus.


positive regulation of cell division

description: Any process that activates or increases the frequency, rate or extent of cell division.


negative regulation of cell division

description: Any process that stops, prevents, or reduces the frequency, rate or extent of cell division.


regulation of nuclear division

description: Any process that modulates the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information.


negative regulation of nuclear division

description: Any process that stops, prevents, or reduces the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information.


positive regulation of nuclear division

description: Any process that activates or increases the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information.


description: Catalysis of the reaction: all-trans-13,14-dihydroretinol + A = all-trans-retinol + AH(2). Note that this reaction has only been observed to occur in the opposite direction.


misfolded protein binding

description: Binding to a misfolded protein.


response to misfolded protein

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a misfolded protein stimulus.


name: short-chain fatty acid biosynthetic process

description: The chemical reactions and pathways resulting in the formation of a short-chain fatty acid. A short-chain fatty acid has an aliphatic tail containing fewer than 6 carbons.


name: medium-chain fatty acid metabolic process

description: The chemical reactions and pathways involving a medium-chain fatty acid. A medium-chain fatty acid has an aliphatic tail containing 6 to 12 carbons.


name: medium-chain fatty acid biosynthetic process

description: The chemical reactions and pathways resulting in the formation of a medium-chain fatty acid. A medium-chain fatty acid has an aliphatic tail containing 6 to 12 carbons.


name: medium-chain fatty acid catabolic process

description: The chemical reactions and pathways resulting in the breakdown of a medium-chain fatty acid. A medium-chain fatty acid has an aliphatic tail containing 6 to 12 carbons.


regulation of timing of catagen

description: Any process that modulates the frequency, rate or extent of timing of catagen, the regression phase of the hair cycle.


name: positive regulation of timing of catagen

description: Any process that activates or increases the frequency, rate or extent of timing of catagen, the regression phase of the hair cycle.


name: negative regulation of timing of catagen

description: Any process that stops, prevents, or reduces the frequency, rate or extent of timing of catagen, the regression phase of the hair cycle.


regulation of hair follicle development

description: Any process that modulates the frequency, rate or extent of hair follicle development.


name: positive regulation of hair follicle development

description: Any process that activates or increases the frequency, rate or extent of hair follicle development.


name: negative regulation of hair follicle development

description: Any process that stops, prevents, or reduces the frequency, rate or extent of hair follicle development.


description: Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 3,4-bisphosphate + H2O = 1-phosphatidyl-1D-myo-inositol 4-phosphate + phosphate.


name: induction by symbiont of tumor or growth in host

description: The process in which a symbiont causes the formation of a mass of cells in a host organism. While these growths are often called nodules, they are not formed as nitrogen-fixing structures, but rather to provide an environment for the symbiont to grow. In this sense they are parasitic structures rather than mutualistic.


name: regulation of synapse structural plasticity

description: Any process that modulates the frequency, rate or extent of synapse structural plasticity. Synapse structural plasticity is a type of cytoskeletal remodeling; this remodeling is induced by stimuli that can lead to long term potentiation and it can be activity-dependent or -independent. Examples of cytoskeletal changes include the formation of new spines and increase in spine size; this can be accompanied by the insertion of greater numbers of glutamate (or other neurotransmitter) receptors into the post-synaptic membrane.


name: negative regulation of synapse structural plasticity

description: Any process that stops, prevents, or reduces the frequency, rate or extent of synapse structural plasticity.


name: positive regulation of synapse structural plasticity

description: Any process that activates, maintains or increases the frequency, rate or extent of synaptic structural plasticity.


cytolysis by host of symbiont cells

description: The killing by an organism of a cell in its symbiont organism by means of the rupture of cell membranes and the loss of cytoplasm. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.


name: translocation of peptides or proteins into symbiont

description: The directed movement of peptides or proteins produced by an organism to a location inside the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.


acquisition of nutrients from symbiont

description: The production of structures and/or molecules in an organism that are required for the acquisition and/or utilization of nutrients obtained from its symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.


modulation by host of symbiont process

description: The process in which an host alters or subverts a process in a symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.


glycolipid binding

description: Binding to a glycolipid, any compound containing one or more monosaccharide residues bound by a glycosidic linkage to a hydrophobic group such as an acylglycerol, a sphingoid, a ceramide (N-acylsphingoid) or a prenyl phosphate.


name: translocation of molecules into symbiont

description: The directed movement of molecule(s) produced by an organism to a location inside the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.


histone H3K36 demethylase activity

description: Catalysis of the removal of a methyl group from a modified lysine residue at position 36 of the histone H3 protein. This is a dioxygenase reaction that is dependent on Fe(II) and 2-oxoglutarate.