name: imaginal disc-derived wing hair outgrowth

description: Extrusion of a cellular projection from the apical membrane of an epithelial cell in an imaginal disc-derived wing. Outgrowth initiates approximately 35 hours after puparium formation from the distal side of the cell, and at this stage the cellular extension is termed a prehair.


name: imaginal disc-derived wing hair elongation

category: biolink:BiologicalProcess biolink:Occurrent biolink:OntologyClass biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: Growth of a prehair in the approximately 10 hour period following its emergence from an epidermal cell in an imaginal disc-derived wing. Prehair elongation is guided and/or driven by the polymerization of actin filaments and the orderly crosslinking of filaments into bundles.


name: imaginal disc-derived wing hair site selection

description: Determination of the site in the cell of an imaginal disc-derived wing at which a prehair initiates outgrowth. Restriction of prehair initiation to the distalmost part of a cell is essential to ensure that each wing epithelial cell produces one adult hair that points distally.


name: maintenance of imaginal disc-derived wing hair orientation

description: Ensuring that hairs in the imaginal disc-derived wing continue to point distally during development, following the initial establishment of wing hair polarity.


name: mesenchymal cell migration involved in limb bud formation

description: The orderly movement of a mesenchymal cell from one site to another that will contribute to the formation of a limb bud.


male germline ring canal

category: biolink:CellularComponent biolink:AnatomicalEntity biolink:PhysicalEssence biolink:OrganismalEntity biolink:SubjectOfInvestigation biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: An intercellular bridge that connects the germline cells of a male cyst.


female germline ring canal

description: An intercellular bridge that connects the germline cells of a female cyst.


Toll-like receptor binding

category: biolink:MolecularActivity biolink:Occurrent biolink:OntologyClass biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: Binding to a Toll-like protein, a pattern recognition receptor that binds pattern motifs from a variety of microbial sources to initiate an innate immune response.


hippo signaling

category: biolink:Pathway biolink:OntologyClass biolink:BiologicalProcess biolink:Occurrent biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: An intracellular signaling cascade that starts with the activation of hippo (STK4/MST1 and STK3/MST2 in mammals and hpo kinase in Drosophila). Hippo then phosphorylates LATS1/2, which in turn phosphoylates the transcriptional co-activator YAP1 (yki in Drosophila), leading to its cytosolic retention and/or degradation.


regulation of hippo signaling

description: Any process that modulates the frequency, rate or extent of hippo signaling.


negative regulation of hippo signaling

description: Any process that stops, prevents, or reduces the frequency, rate or extent of hippo signaling.


positive regulation of hippo signaling

description: Any process that activates or increases the frequency, rate or extent of hippo signaling.


name: Notch receptor processing, ligand-dependent

description: The proteolytic cleavages to the Notch protein that occur as a result of ligand binding. Ligand binding at the cell surface exposes an otherwise inaccessible cleavage site in the extracellular portion of Notch, which when cleaved releases a membrane-tethered form of the Notch intracellular domain. Subsequent cleavage within the transmembrane domain then leads to the release of the soluble Notch intracellular domain (NICD).


name: Notch receptor processing, ligand-independent

description: The proteolytic cleavages to the Notch protein that occur prior to ligand binding. A primary cleavage event within the extracellular domain whilst the Notch protein in still in the secretory pathway, leads to the transportation of a processed heterodimer to the cell surface.


peptidyl-tyrosine dephosphorylation

description: The removal of phosphoric residues from peptidyl-O-phospho-tyrosine to form peptidyl-tyrosine.


name: long-chain fatty-acyl-CoA metabolic process

description: The chemical reactions and pathways involving long-chain fatty-acyl-CoAs, any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a long-chain fatty-acyl group. A long-chain fatty acid has an aliphatic tail containing 13 to 22 carbons.


fatty-acyl-CoA metabolic process

description: The chemical reactions and pathways involving a fatty-acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with a fatty-acyl group.


name: long-chain fatty-acyl-CoA biosynthetic process

description: The chemical reactions and pathways resulting in the formation of a long-chain fatty-acyl-CoA any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a long-chain fatty-acyl group. A long-chain fatty acid has an aliphatic tail containing 13 to 22 carbons.


inosine transport

description: The directed movement of the purine ribonucleoside inosine, also known as hypoxanthine riboside, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


regulation of inosine transport

description: Any process that modulates the frequency, rate or extent of the directed movement of inosine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


name: positive regulation of inosine transport

description: Any process that activates or increases the frequency, rate or extent of the directed movement of inosine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


name: negative regulation of inosine transport

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of inosine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


hypoxanthine transport

description: The directed movement of hypoxanthine, 6-hydroxypurine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


regulation of hypoxanthine transport

description: Any process that modulates the frequency, rate or extent of the directed movement of hypoxanthine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


name: positive regulation of hypoxanthine transport

description: Any process that activates or increases the frequency, rate or extent of the directed movement of hypoxanthine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


name: negative regulation of hypoxanthine transport

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of hypoxanthine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


acetyl-CoA transmembrane transport

description: The process in which acetyl-CoA is transported across a membrane. Acetyl-CoA is a derivative of coenzyme A in which the sulfhydryl group is acetylated; it is a metabolite derived from several pathways (e.g. glycolysis, fatty acid oxidation, amino-acid catabolism) and is further metabolized by the tricarboxylic acid cycle. It is a key intermediate in lipid and terpenoid biosynthesis.


coenzyme A transmembrane transport

description: The process in which coenzyme A is transported across a membrane. Coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, is an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester.


FAD transmembrane transport

description: The process in which flavin-adenine dinucleotide (FAD) is transported across a membrane. FAD forms the coenzyme of the prosthetic group of various flavoprotein oxidoreductase enzymes, in which it functions as an electron acceptor by being reversibly converted to its reduced form.


heme transmembrane transport

description: The process in which heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring, is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.


NAD transmembrane transport

description: The process in which a nicotinamide adenine dinucleotide is transported across a membrane; transport may be of either the oxidized form, NAD, or the reduced form, NADH.


name: nicotinamide mononucleotide transmembrane transport

description: The process in which nicotinamide mononucleotide is transported across a membrane. Nicotinamide mononucleotide is a ribonucleotide in which the nitrogenous base, nicotinamide, is in beta-n-glycosidic linkage with the c-1 position of d-ribose. It is a constituent of NAD and NADP.


name: Toll-like receptor 1-Toll-like receptor 2 protein complex

description: A heterodimeric protein complex containing Toll-like receptor 1 (TLR1) and Toll-like receptor 2 (TLR2).


name: Toll-like receptor 2-Toll-like receptor 6 protein complex

description: A heterodimeric protein complex containing Toll-like receptor 2 (TLR2) and Toll-like receptor 6 (TLR6).


intracellular triglyceride homeostasis

description: A homeostatic process involved in the maintenance of a steady state level of triglyceride within a cell.


name: peroxisome proliferator activated receptor signaling pathway

description: A nuclear receptor-mediated signaling pathway initiated by a ligand binding to an intracellular peroxisome proliferator activated receptor (alpha, beta or gamma) of the nuclear receptor protein family, and ending with regulation of a downstream cellular process, e.g. transcription.


name: regulation of peroxisome proliferator activated receptor signaling pathway

description: Any process that modulates the frequency, rate or extent of the peroxisome proliferator activated receptor signaling pathway.


name: negative regulation of peroxisome proliferator activated receptor signaling pathway

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the peroxisome proliferator activated receptor signaling pathway.


name: positive regulation of peroxisome proliferator activated receptor signaling pathway

description: Any process that activates or increases the frequency, rate or extent of the peroxisome proliferator activated receptor signaling pathway.


Cul8-RING ubiquitin ligase complex

description: A ubiquitin ligase complex in which a cullin from the Cul8 subfamily and a RING domain protein form the catalytic core. In S. cerevisiae, Mms1p acts as the adaptor protein and substrate specificity is conferred by any of a number of different proteins.


protein-DNA ISRE complex assembly

description: The aggregation, arrangement and bonding together of proteins and DNA molecules to form a protein-DNA complex, in which the complex is formed through interaction of the protein(s) with a interferon-stimulated response element (ISRE) in the DNA.


histone locus body

description: A nuclear body associated with the histone gene locus that is thought to contain all of the factors necessary for histone mRNA transcription and pre-mRNA processing. In Drosophila, U7 snRNP is located in the histone locus body rather than the distinct Cajal body.


thymine transport

description: The directed movement of thymine, 5-methyluracil, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


regulation of thymine transport

description: Any process that modulates the frequency, rate or extent of the directed movement of thymine, 5-methyluracil, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


name: negative regulation of thymine transport

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of thymine, 5-methyluracil, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


name: positive regulation of thymine transport

description: Any process that activates or increases the frequency, rate or extent of the directed movement of thymine, 5-methyluracil, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


name: selenocysteine insertion sequence binding

description: Binding to a selenocysteine insertion sequence (SECIS), a regulatory sequence within mRNA which directs incorporation of a selenocysteine at a stop codon (UGA) during translation.


pre-B cell receptor complex

description: An immunoglobulin-like complex that is present in at least the plasma membrane of pre-B cells, and that is composed of two identical immunoglobulin heavy chains and two surrogate light chains, each composed of the lambda-5 and VpreB proteins, and a signaling subunit, a heterodimer of the Ig-alpha and Ig-beta proteins.


microtubule plus-end

description: The growing (plus) end of a microtubule. In vitro, microtubules polymerize more quickly at the plus end than at the minus end. In vivo, microtubule growth occurs only at the plus end, and the plus end switches between periods of growth and shortening, a behavior known as dynamic instability.


protein localization to microtubule

description: A process in which a protein is transported to, or maintained at, a microtubule.


name: chondroitin sulfate proteoglycan binding

description: Binding to a chondroitin sulfate proteoglycan, any proteoglycan containing chondroitin sulfate as the glycosaminoglycan carbohydrate unit.


chondroitin sulfate binding

description: Binding to chondroitin sulfate, a glycosaminoglycan made up of two alternating monosaccharides: D-glucuronic acid (GlcA) and N-acetyl-D-galactosamine (GalNAc).


zymogen binding

description: Binding to a zymogen, an enzymatically inactive precursor of an enzyme that is often convertible to an active enzyme by proteolysis.


sterol import

description: The directed movement of a sterol into a cell or organelle. Sterols are steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule.


transepithelial water transport

description: The directed movement of water (H2O) from one side of an epithelium to the other.


carbon dioxide transmembrane transport

description: The process in which carbon dioxide (CO2) is transported across a membrane.


name: carbon dioxide transmembrane transporter activity

description: Enables the transfer of carbon dioxide (CO2) from one side of a membrane to the other.


name: very long-chain-3-hydroxyacyl-CoA dehydrogenase activity

description: Catalysis of the reaction: (S)-3-hydroxyacyl-CoA + NAD(P)+ = 3-oxoacyl-CoA + NAD(P)H + H+, where the acyl group is a very long-chain fatty acid residue. A very long-chain fatty acid has an aliphatic tail containing more than 22 carbons.


ATP-gated ion channel activity

description: Enables the transmembrane transfer of an ion by a channel that opens when ATP has been bound by the channel complex or one of its constituent parts.


sterol transmembrane transport

description: The process in which a sterol is transported across a membrane. Sterols are steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule.


thioester metabolic process

description: The chemical reactions and pathways involving a thioester, a compound of general formula RC(=O)SR' in which the linking oxygen in an ester is replaced by a sulfur atom. They are the product of esterification between a carboxylic acid and a thiol.


thioester biosynthetic process

description: The chemical reactions and pathways resulting in the formation of a thioester, a compound of general formula RC(=O)SR' in which the linking oxygen in an ester is replaced by a sulfur atom. They are the product of esterification between a carboxylic acid and a thiol.


Roundabout signaling pathway

description: The series of molecular signals initiated by a SLIT protein binding to a Roundabout (ROBO) family receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.


name: regulation of Roundabout signaling pathway

description: Any process that modulates the frequency, rate or extent of the Roundabout signaling pathway.


name: negative regulation of Roundabout signaling pathway

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the Roundabout signaling pathway.


name: positive regulation of Roundabout signaling pathway

description: Any process that activates or increases the frequency, rate or extent of the Roundabout signaling pathway.


name: chemokine (C-X-C motif) ligand 9 production

description: The appearance of chemokine (C-X-C motif) ligand 9 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


name: regulation of chemokine (C-X-C motif) ligand 9 production

description: Any process that modulates the frequency, rate, or extent of production of chemokine (C-X-C motif) ligand 9.


name: negative regulation of chemokine (C-X-C motif) ligand 9 production

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of production of chemokine (C-X-C motif) ligand 9.


name: positive regulation of chemokine (C-X-C motif) ligand 9 production

description: Any process that activates or increases the frequency, rate, or extent of production of chemokine (C-X-C motif) ligand 9.


name: helper T cell enhancement of adaptive immune response

description: Positive regulation of an adaptive immune response mediated via cytokine production by helper T cell.


name: helper T cell enhancement of T cell mediated immune response

description: Positive regulation of a T cell mediated immune response mediated via cytokine production by a helper T cell.


name: helper T cell enhancement of B cell mediated immune response

description: Positive regulation of a B cell mediated immune response mediated via cytokine production by a helper T cell.


histone H3Y41 kinase activity

description: Catalysis of the reaction: histone H3-tyrosine (position 41) + ATP = histone H3-phosphotyrosine (position 41) + ADP. This reaction is the addition of a phosphate group to the tyrosine residue at position 41 of histone H3.


histone H3T11 kinase activity

description: Catalysis of the reaction: histone H3-threonine (position 11) + ATP = histone H3-phosphothreonine (position 11) + ADP. This reaction is the addition of a phosphate group to the threonine residue at position 11 of histone H3.


histone H3T6 kinase activity

description: Catalysis of the reaction: histone H3-threonine (position 6) + ATP = histone H3-phosphothreonine (position 6) + ADP. This reaction is the addition of a phosphate group to the threonine residue at position 6 of histone H3.


description: Catalysis of the reaction: 5alpha-dihydrotestosterone + NAD+ = 5alpha-androstane-3,17-dione + NADH.


protein localization to synapse

description: Any process in which a protein is transported to, and/or maintained at the synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell.


autocrine signaling

description: Signaling between cells of the same type. The signal produced by the signaling cell binds to a receptor on, and affects a cell of the same type.


extracellular matrix-cell signaling

description: Any process that mediates the transfer of information between the extracellular matrix and a cell.


gluconate transmembrane transport

description: The process in which gluconate is transported across a membrane. Gluconate is the aldonic acid derived from glucose.


name: regulation of gluconate transmembrane transport

description: Any process that modulates the frequency, rate or extent of the directed movement of a gluconate across a membrane by means of some agent such as a transporter or pore.


name: negative regulation of gluconate transmembrane transport

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of gluconate across a membrane by means of some agent such as a transporter or pore.


name: positive regulation of gluconate transmembrane transport

description: Any process that activates or increases the frequency, rate or extent of the directed movement of gluconate across a membrane by means of some agent such as a transporter or pore.


acetate transmembrane transport

description: The process in which acetate is transported across a membrane. Acetate is the 2-carbon carboxylic acid ethanoic acid.


copper ion transmembrane transport

description: The directed movement of copper cation across a membrane.


phosphate ion transmembrane transport

description: The process in which a phosphate is transported across a membrane.


name: triose phosphate transmembrane transport

description: The process in which triose phosphate (glyceraldehyde 3-phosphate) is transported across a membrane. Glyceraldehyde 3-phosphate is any organic three carbon compound phosphate ester.


name: maintenance of protein localization in endoplasmic reticulum

description: Any process in which a protein is maintained in the endoplasmic reticulum and prevented from moving elsewhere. These include sequestration within the endoplasmic reticulum, protein stabilization to prevent transport elsewhere and the active retrieval of proteins that escape the endoplasmic reticulum.


cyclic-di-GMP binding

description: Binding to cyclic-di-GMP, cyclic dimeric guanosine monophosphate.


description: Catalysis of the reaction: geranylgeranyl diphosphate = halima-5(6),13-dien-15-yl diphosphate.


tuberculosinol biosynthetic process

description: The chemical reactions and pathways resulting in the formation of tuberculosinol (halima-5,6,dien-15-ol), a secondary metabolite in Mycobacteria.


name: cell migration involved in vasculogenesis

description: The orderly movement of a cell from one site to another that will contribute to the differentiation of an endothelial cell that will form de novo blood vessels and tubes.


dipeptide transmembrane transport

description: The directed movement of a dipeptide across a membrane by means of some agent such as a transporter or pore. A dipeptide is a combination of two amino acids linked together by a peptide (-CO-NH-) bond.


tripeptide transmembrane transport

description: The directed movement of a tripeptide across a membrane by means of some agent such as a transporter or pore. A tripeptide is a compound containing three amino acids linked together by peptide bonds.


nickel cation transmembrane transport

description: The directed movement of nickel (Ni) cations across a membrane by means of some agent such as a transporter or pore.


borate transmembrane transport

description: The process in which borate is transported across a membrane. Borate is the anion (BO3)3-; boron is a group 13 element, with properties which are borderline between metals and non-metals.


description: Catalysis of the reaction: 1-(2-amino-2-deoxy-alpha-D-glucopyranoside)-1D-myo-inositol + L-cysteine + ATP = 1-D-myo-inosityl-2-L-cysteinylamido-2-deoxy-alpha-D-glucopyranoside + AMP + diphosphate + 2 H+. 1-(2-amino-2-deoxy-alpha-D-glucopyranoside)-1D-myo-inositol is also known as glucosaminyl-inositol or GlcN-Ins, and 1-D-myo-inosityl-2-L-cysteinylamido-2-deoxy-alpha-D-glucopyranoside as desacetylmycothiol or Cys-GlcN-Ins.


mycothiol synthase activity

description: Catalysis of the reaction: 1D-myo-inositol-2-(L-cysteinylamido)-2-deoxy-alpha-D-glucopyranoside + acetyl-CoA = mycothiol + coA + H+. Mycothiol is also known as AcCys-GlcN-Ins and 1-D-myo-inosityl-2-L-cysteinylamido-2-deoxy-alpha-D-glucopyranoside as Cys-GlcN-Ins or desacetylmycothiol.


name: extrinsic component of thylakoid membrane

description: The component of a thylakoid membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.


name: extrinsic component of plastid thylakoid membrane

description: The component of a plastid thylakoid membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.


name: extrinsic component of lumenal side of plastid thylakoid membrane

description: The component of a plastid thylakoid membrane consisting of gene products and protein complexes that are loosely bound to its lumenal surface, but not integrated into the hydrophobic region.


name: extrinsic component of stromal side of plastid thylakoid membrane

description: The component of a plastid thylakoid membrane consisting of gene products and protein complexes that are loosely bound to its stromal surface, but not integrated into the hydrophobic region.


extrinsic component of plastid membrane

description: The component of a plastid membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.


name: extrinsic component of plastid inner membrane

description: The component of a plastid inner membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.


name: extrinsic component of stromal side of plastid inner membrane

description: The component of a plastid inner membrane consisting of gene products and protein complexes that are loosely bound to its stromal surface, but not integrated into the hydrophobic region.


response to interferon-alpha

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-alpha stimulus. Interferon-alpha is a type I interferon.


response to interferon-beta

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-beta stimulus. Interferon-beta is a type I interferon.


cellular response to interferon-alpha

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-alpha stimulus. Interferon-alpha is a type I interferon.


cellular response to interferon-beta

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-beta stimulus. Interferon-beta is a type I interferon.


vesicle cargo loading

description: The formation of a macromolecular complex between the coat proteins and proteins and/or lipoproteins that are going to be transported by a vesicle.


name: L-ascorbate 6-phosphate lactonase activity

description: Catalysis of the reaction: L-ascorbate 6-phosphate + H2O = 3-keto-L-gulonate 6-phosphate.


vitamin transmembrane transport

description: The process in which a vitamin is transported across a membrane. A vitamin is one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body.


name: determination of left/right asymmetry in diencephalon

description: The establishment of the diencephalon with respect to the left and right halves.


name: determination of pancreatic left/right asymmetry

description: Determination of the asymmetric location of the pancreas with respect to the left and right halves of the organism.


name: positive regulation of vascular wound healing

description: Any process that increases the rate, frequency, or extent of blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels and contribute to the series of events that restore integrity to damaged vasculature.


name: luteinizing hormone signaling pathway involved in ovarian follicle development

description: The series of molecular signals initiated by luteinizing hormone binding to a receptor, where the activated receptor signals via downstream effectors that contribute to progression of the ovarian follicle over time, from its formation to the mature structure.


name: choriogonadotropin hormone receptor activity

description: Combining with the choriogonadotropin hormone to initiate a change in cell activity.


lipase binding

description: Binding to a lipase.


selective angioblast sprouting

description: The segregation of angioblasts into discrete arterial and venous vessels from one common precursor vessel.


name: angioblast cell migration involved in selective angioblast sprouting

description: The directional migration of angioblast cells as part of selective angioblast sprouting, which results in angioblast segregation into arterial and venous populations.


angioblast cell migration

description: The orderly movement of angioblasts, cells involved in blood vessel morphogenesis.


name: regulation of angioblast cell migration involved in selective angioblast sprouting

description: Any process that modulates the frequency, rate or extent of angioblast cell migration involved in selective angioblast sprouting.


chylomicron binding

description: Binding to a chylomicron, a large lipoprotein particle (diameter 75-1200 nm) composed of a central core of triglycerides and cholesterol surrounded by a protein-phospholipid coating. The proteins include one molecule of apolipoprotein B-48 and may include a variety of apolipoproteins, including APOAs, APOCs and APOE.


name: angioblast cell migration from lateral mesoderm to midline

description: The directed movement of angioblasts from the lateral mesoderm to the midline which occurs as part of the formation of the early midline vasculature.


gastric motility

description: The spontaneous peristaltic movements of the stomach that aid in digestion, moving food through the stomach and out through the pyloric sphincter into the duodenum.


gastric emptying

description: The process in which the liquid and liquid-suspended solid contents of the stomach exit through the pylorus into the duodenum.


adenine/adenine mispair binding

description: Binding to a double-stranded DNA region containing an A/A mispair.


adenine/guanine mispair binding

description: Binding to a double-stranded DNA region containing an A/G mispair.


cytosine/cytosine mispair binding

description: Binding to a double-stranded DNA region containing a C/C mispair.


thymine/thymine mispair binding

description: Binding to a double-stranded DNA region containing a T/T mispair.


cytosine/thymine mispair binding

description: Binding to a double-stranded DNA region containing a C/T mispair.


guanine/guanine mispair binding

description: Binding to a double-stranded DNA region containing a G/G mispair.


name: regulation of leukotriene production involved in inflammatory response

description: Any process that modulates the rate, frequency or extent of the synthesis or release of any leukotriene following a stimulus as part of an inflammatory response.


name: positive regulation of leukotriene production involved in inflammatory response

description: Any process that increases the rate, frequency or extent of the synthesis or release of any leukotriene following a stimulus as part of an inflammatory response.


name: negative regulation of leukotriene production involved in inflammatory response

description: Any process that decreases the rate, frequency or extent of the synthesis or release of any leukotriene following a stimulus as part of an inflammatory response.


SNARE complex assembly

description: The aggregation, arrangement and bonding together of a set of components to form a SNARE complex, a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers.


SNARE complex disassembly

description: The disaggregation of the SNARE protein complex into its constituent components. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers.


regulation of SNARE complex disassembly

description: Any process that modulates the frequency, rate or extent of disassembly of the SNARE complex. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers.


description: Catalysis of the reaction: UDP-galactose + lipopolysaccharide = UDP + 1,5 alpha-D-galactosyl-lipopolysaccharide.


cAMP response element binding

description: Binding to a cyclic AMP response element (CRE), a short palindrome-containing sequence found in the promoters of genes whose expression is regulated in response to cyclic AMP.


carnosine metabolic process

description: The chemical reactions and pathways involving the dipeptide beta-alanyl-L-histidine (carnosine).


carnosine biosynthetic process

description: The chemical reactions and pathways resulting in the formation of the dipeptide beta-alanyl-L-histidine (carnosine).


MH2 domain binding

description: Binding to a MH2 (MAD homology 2) protein domain. The MH2 domain is found at the carboxy-terminus of MAD related proteins such as Smads. The MH2 domain mediates interaction with a wide variety of proteins and provides specificity and selectivity to Smad function and also is critical for mediating interactions in Smad oligomers.


MH1 domain binding

description: Binding to a MH1 (MAD homology 1) protein domain. The MH1 domain is found at the amino terminus of MAD related proteins such as Smads and can mediate DNA binding in some proteins. Smads also use the MH1 domain to interact with some transcription factors.


name: metanephric part of ureteric bud development

description: The development of the portion of the ureteric bud tube that contributes to the morphogenesis of the metanephros.


ureter part of ureteric bud development

description: The development of the portion of the ureteric bud that contributes to the morphogenesis of the ureter. The ureter ureteric bud is the initial structure that forms the ureter.


name: regulation of myosin light chain kinase activity

description: Any process that modulates the frequency, rate or extent of myosin light chain kinase activity.


name: positive regulation of myosin light chain kinase activity

description: Any process that activates or increases the frequency, rate or extent of myosin light chain kinase activity.


name: negative regulation of myosin light chain kinase activity

description: Any process that stops, prevents, or reduces the frequency, rate or extent of myosin light chain kinase activity.


name: regulation of myosin-light-chain-phosphatase activity

description: Any process that modulates the frequency, rate or extent of myosin-light-chain-phosphatase activity.


name: positive regulation of myosin-light-chain-phosphatase activity

description: Any process that activates or increases the frequency, rate or extent of myosin-light-chain-phosphatase activity.


name: negative regulation of myosin-light-chain-phosphatase activity

description: Any process that stops, prevents, or reduces the frequency, rate or extent of myosin-light-chain-phosphatase activity.


DNA dealkylation

description: The removal of an alkyl group from one or more nucleotides within an DNA molecule.


oxidative RNA demethylation

description: The removal of the methyl group from one or more nucleotides within an RNA molecule involving oxidation (i.e. electron loss) of one or more atoms.


DNA demethylase activity

description: Catalysis of the removal of a methyl group from one or more nucleosides within a DNA molecule.


oxidative RNA demethylase activity

description: Catalysis of the removal of a methyl group from one or more nucleosides within a RNA molecule involving the oxidation (i.e. electron loss) of one or more atoms.


name: broad specificity oxidative DNA demethylase activity

description: Catalysis of the reaction: a methylated nucleobase within DNA + 2-oxoglutarate + O2 = a nucleobase within DNA + formaldehyde + succinate + CO2. Catalyzes oxidative demethylation of the DNA base lesions N1- methyladenine, N3-methylcytosine, N1-methylguanine, and N3- methylthymine. Can also act of RNA.


PR-DUB complex

description: A multimeric protein complex that removes monoubiquitin from histone H2A. In Drosophila and mammals, the core of the complex is composed of Calypso/BAP1 and Asx/ASXL1, respectively.


protein K29-linked ubiquitination

description: A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 29 of the ubiquitin monomers, is added to a protein. K29-linked ubiquitination targets the substrate protein for degradation.


description: The removal of the ubiquitin group from a monoubiquitinated protein.


protein K29-linked deubiquitination

description: A protein deubiquitination process in which a K29-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 29 of the ubiquitin monomers, is removed from a protein.


proline transmembrane transport

description: The directed movement of proline, pyrrolidine-2-carboxylic acid, across a membrane by means of some agent such as a transporter or pore.


NF-kappaB p50/p65 complex

description: A heterodimer of NF-kappa B p50 and p65 subunits.


name: retrograde transport, plasma membrane to Golgi

description: The directed movement of substances from the plasma membrane back to the trans-Golgi network, mediated by vesicles.


name: 3-hydroxypropionate dehydrogenase (NADP+) activity

description: Catalysis of the reaction: 3-hydroxypropanoate + NADP+ = 3-oxopropanoate + H+ + NADPH.


NADH pyrophosphatase activity

description: Catalysis of the reaction: NADH + H2O = AMP + NMNH + 2 H+.


name: chemokine (C-C motif) ligand 6 production

description: The appearance of chemokine (C-C motif) ligand 6 (CCL6) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


name: regulation of chemokine (C-C motif) ligand 6 production

description: Any process that modulates the frequency, rate, or extent of production of chemokine (C-C motif) ligand 6 (CCL6).


name: negative regulation of chemokine (C-C motif) ligand 6 production

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of production of chemokine (C-C motif) ligand 6 (CCL6).


name: positive regulation of chemokine (C-C motif) ligand 6 production

description: Any process that activates or increases the frequency, rate, or extent of production of chemokine (C-C motif) ligand 6 (CCL6).


carbohydrate response element binding

description: Binding to a carbohydrate response element (ChoRE) found in the promoters of genes whose expression is regulated in response to carbohydrates, such as the triglyceride synthesis genes.


name: 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity

description: Catalysis of the reaction: 8-oxo-7,8-dihydrodeoxyguanosine-triphosphate (8-oxo-dGTP) + H2O = 8-oxo-7,8-dihydrodeoxyguanosine phosphate (8-oxo-dGMP) + diphosphate. 8-oxo-dGTP is the oxidised form of the free guanine nucleotide and can act as a potent mutagenic substrate for DNA synthesis causing transversion mutations. 8-oxo-dGTPase hydrolyses 8-oxo-dGTP to its monophosphate form to prevent the misincorporation of 8-oxo-dGTP into cellular DNA.


name: positive regulation of SNARE complex disassembly

description: Any process that increases the frequency, rate or extent of disassembly of the SNARE complex. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers.


name: negative regulation of SNARE complex disassembly

description: Any process that decreases the frequency, rate or extent of disassembly of the SNARE complex. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers.


regulation of SNARE complex assembly

description: Any process that modulates the frequency, rate or extent of assembly of the SNARE complex. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers.


name: positive regulation of SNARE complex assembly

description: Any process that increases the frequency, rate or extent of assembly of the SNARE complex. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers.


name: negative regulation of SNARE complex assembly

description: Any process that decreases the frequency, rate or extent of assembly of the SNARE complex. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers.


name: determination of left/right asymmetry in nervous system

description: The establishment of the nervous system with respect to the left and right halves.


urease complex

description: A multiprotein nickel-containing complex that possesses urease activity (catalysis of the hydrolysis of urea to ammonia and carbon dioxide).


name: termination of Roundabout signal transduction

description: The signaling process in which signaling from the receptor ROBO is brought to an end, rather than being reversibly modulated.


intracellular signal transduction

description: The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell.


pheophorbidase activity

description: Catalysis of the reaction: pheophorbide a + H2O = pyropheophorbide a + methanol + CO2. The reaction occurs in two steps; pheophoridase catalyzes the conversion of pheophorbide a to a precursor of pyropheophorbide a, C-13(2)-carboxylpyropheophorbide a, by demethylation, and then the precursor is decarboxylated non-enzymatically to yield pyropheophorbide a.


regulation of chromatin binding

description: Any process that modulates the frequency, rate or extent of chromatin binding. Chromatin binding is the selective interaction with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.


name: negative regulation of chromatin binding

description: Any process that stops or reduces the frequency, rate or extent of chromatin binding. Chromatin binding is the selective interaction with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.


name: positive regulation of chromatin binding

description: Any process that increases the frequency, rate or extent of chromatin binding. Chromatin binding is the selective interaction with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.


regulation of kidney size

description: Any process that modulates the size of a kidney.


regulation of pronephros size

description: Any process that modulates the size of a pronephric kidney.


regulation of metanephros size

description: Any process that modulates the size of a metanephric kidney.


non-canonical Wnt signaling pathway

description: A type of Wnt signaling pathway in which Wnt binding to its receptor on the surface of a target cell results in the by propagation of the molecular signals via effectors other than beta-catenin.


N-terminal peptidyl-proline methylation

description: The methylation of the N-terminal proline of proteins.


N-terminal peptidyl-serine methylation

description: The methylation of the N-terminal serine of proteins.


description: The monomethylation of the N-terminal serine of proteins to form the derivative N-methylserine.


description: The dimethylation of the N-terminal serine of proteins to form the derivative N,N-dimethylserine.


description: The trimethylation of the N-terminal serine of proteins to form the derivative N,N,N-trimethylserine.


histone H4K20 demethylase activity

description: Catalysis of the removal of the methyl group from a modified lysine residue at position 20 of the histone H4 protein. This is a dioxygenase reaction that is dependent on Fe(II) and 2-oxoglutarate.


azurophil granule membrane

description: The lipid bilayer surrounding an azurophil granule, a primary lysosomal granule found in neutrophil granulocytes that contains a wide range of hydrolytic enzymes and is released into the extracellular fluid.


azurophil granule lumen

description: The volume enclosed by the membrane of an azurophil granule, a primary lysosomal granule found in neutrophil granulocytes that contains a wide range of hydrolytic enzymes and is released into the extracellular fluid.


specific granule membrane

description: The lipid bilayer surrounding a specific granule, a granule with a membranous, tubular internal structure, found primarily in mature neutrophil cells. Most are released into the extracellular fluid. Specific granules contain lactoferrin, lysozyme, vitamin B12 binding protein and elastase.


specific granule lumen

description: The volume enclosed by the membrane of a specific granule, a granule with a membranous, tubular internal structure, found primarily in mature neutrophil cells. Most are released into the extracellular fluid. Specific granules contain lactoferrin, lysozyme, vitamin B12 binding protein and elastase.


name: sequestering of extracellular ligand from receptor

description: The process of binding or confining an extracellular signaling ligand, such that the ligand is unable to bind to its cell surface receptor.


name: sequestering of BMP in extracellular matrix

description: Confining a bone morphogenetic protein (BMP) to the extracellular matrix (ECM), such that it is separated from other components of the signaling pathway, including its cell surface receptor. Bone morphogenetic proteins (BMPs) are secreted as homodimers, non-covalently associated with N-terminal pro-peptides, and are targeted to the extracellular matrix through interaction with matrix proteins.


name: sequestering of TGFbeta in extracellular matrix

description: Confining TGFbeta to the extracellular matrix (ECM) such that it is separated from other components of the signaling pathway, including its cell surface receptor. TGFbeta is secreted as part of a latent complex that is targeted to the extracellular matrix through latent-TGFbeta-binding protein (LTBP)-mediated association with matrix proteins.


name: G protein-coupled purinergic receptor signaling pathway

description: A G protein-coupled receptor signaling pathway initiated by an extracellular purine or purine derivative binding to its receptor, and ending with the regulation of a downstream cellular process.


name: G protein-coupled purinergic nucleotide receptor signaling pathway

description: A G protein-coupled receptor signaling pathway initiated by an extracellular purine nucleotide binding to its receptor, and ending with the regulation of a downstream cellular process.


name: purinergic nucleotide receptor signaling pathway

description: The series of molecular signals initiated by an extracellular purine nucleotide binding to its receptor, and ending with the regulation of a downstream cellular process, e.g. transcription.


signaling adaptor activity

description: The binding activity of a molecule that brings together two or more molecules in a signaling pathway, permitting those molecules to function in a coordinated way. Adaptor molecules themselves do not have catalytic activity.


name: establishment of protein localization to extracellular region

description: The directed movement of a protein to a specific location within the extracellular region.


name: positive regulation of Wnt signaling pathway by establishment of Wnt protein localization to extracellular region

description: Any process that activates or increases the frequency, rate or extent of the Wnt signaling pathway by the directed movement of a Wnt protein within the extracellular region.


ganglioside binding

description: Binding to a ganglioside, a ceramide oligosaccharide carrying in addition to other sugar residues, one or more sialic acid residues.


description: Catalysis of the reaction: 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside + H2O = 1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside + acetate. This reaction is the hydrolysis of an acetyl group from N-acetylglucosaminylinositol.


methylthiotransferase activity

description: Catalysis of the addition of a methylthioether group (-SCH3) to a nucleic acid or protein acceptor.


description: Catalysis of the methylthiolation (-SCH3 addition) at the C2 of the adenosine ring of N6-isopentenyladenosine (i6A) in tRNA, to form 2-methylthio-N6-isopentenyladenosine (ms2i6A).


description: Catalysis of the methylthiolation (-SCH3 addition) at the C2 of the adenosine ring of N6-threonylcarbomyladenosine (t6A) in tRNA, to form 2-methylthio-N6-threonylcarbamoyladenosine (ms2t6A).


name: aspartic acid methylthiotransferase activity

description: Catalysis of the methylthiolation (-SCH3 addition) of the beta-carbon of peptidyl-aspartic acid to form peptidyl-L-beta-methylthioaspartic acid.


tRNA methylthiolation

description: The addition of a methylthioether group (-SCH3) to a nucleotide in a tRNA molecule.


protein deacylation

description: The removal of an acyl group, any group or radical of the form RCO- where R is an organic group, from a protein amino acid.


name: fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow cell

description: The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands, which stops, prevents, or reduces the frequency, rate or extent of the occurrence or rate of cell death by apoptotic process in the bone marrow.


name: fibroblast growth factor receptor signaling pathway involved in hemopoiesis

description: The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands, which contributes to hemopoiesis.


name: fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow

description: The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands, which activates or increases the frequency, rate or extent of cell proliferation in the bone marrow.


description: Catalysis of the transfer of a nitric oxide (NO) group to a sulphur atom within a cysteine residue of a protein.


peptidyl-cysteine S-trans-nitrosylation

description: Transfer of a nitric oxide (NO) group from one cysteine residue to another.


name: fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development

description: The series of molecular signals generated as a consequence of a fibroblast growth factor-type receptor binding to one of its physiological ligands, which contributes to the progression of the orbitofrontal cortex over time from its initial formation until its mature state.


protein deglutamylation

description: The removal of a glutamate residue from a protein. Glutamate residues in proteins can be gene-encoded, or added as side chains during the protein modification process of polyglutamylation.


C-terminal protein deglutamylation

description: The removal of a C-terminal, gene-encoded glutamate residue from a protein.


protein side chain deglutamylation

description: The removal of a glutamate residue from the side chain of a protein. Glutamate side chains are added to glutamic acid residues within the primary protein sequence during polyglutamylation.


protein branching point deglutamylation

description: The removal of a branching point glutamate residue. A branching point glutamate connects a glutamate side chain to a gene-encoded glutamate residue.


AP-2 adaptor complex binding

description: Binding to an AP-2 adaptor complex. The AP-2 adaptor complex is a heterotetrameric AP-type membrane coat adaptor complex that consists of alpha, beta2, mu2 and sigma2 subunits and links clathrin to the membrane surface of a vesicle. In at least humans, the AP-2 complex can be heterogeneric due to the existence of multiple subunit isoforms encoded by different alpha genes (alphaA and alphaC).


RNA stem-loop binding

description: Binding to a stem-loop in an RNA molecule. An RNA stem-loop is a secondary RNA structure consisting of a double-stranded RNA (dsRNA) stem and a terminal loop.


snRNA stem-loop binding

description: Binding to a stem-loop in a small nuclear RNA (snRNA). An RNA stem-loop is a secondary RNA structure consisting of a double-stranded RNA (dsRNA) stem and a terminal loop.


clathrin adaptor activity

description: Bringing together a cargo protein with clathrin, responsible for the formation of endocytic vesicles.


stress granule disassembly

description: The disaggregation of a stress granule into its constituent protein and RNA parts.


root hair

description: A long, thin projection from a root epidermal cell that contains F-actin and tubulin, and a cell wall.


root hair tip

description: The tip portion of an outgrowth of a root epidermal cell.


ER to Golgi ceramide transport

description: The directed movement of a ceramide from the endoplasmic reticulum (ER) to the Golgi. Ceramides are a class of lipid composed of sphingosine linked to a fatty acid.


intrahepatic bile duct development

description: The progression of the intrahepatic bile ducts over time, from their formation to the mature structure. Intrahepatic bile ducts (bile ducts within the liver) collect bile from bile canaliculi in the liver, and connect to the extrahepatic bile ducts (bile ducts outside the liver).


renal glucose absorption

description: A renal system process in which glucose is taken up from the collecting ducts and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures.


receptor transactivation

description: The process in which a receptor is activated by another receptor. Receptor transactivation can occur through different mechanisms and includes cross-talk between signaling pathways where one receptor activates a receptor for a different ligand, and also activation of subunits within a receptor oligomer.


name: juvenile hormone mediated signaling pathway

description: The series of molecular signals initiated by a juvenile hormone binding to its receptor, a bHLH-PAS transcription factor, to regulate gene expression.


ceramide transport

description: The directed movement of ceramides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Ceramides are a class of lipid composed of sphingosine linked to a fatty acid.


cystic duct development

description: The progression of the cystic duct over time, from its formation to the mature structure. The cystic duct runs from the gallbladder to the common bile duct.


name: N-terminal protein amino acid N-linked glycosylation

description: Addition of a carbohydrate or carbohydrate derivative unit via a nitrogen (N) atom of the N-terminal amino acid of a protein.


name: bone mineralization involved in bone maturation

description: The deposition of hydroxyapatite, involved in the progression of the skeleton from its formation to its mature state.


CD40 receptor complex

description: A protein complex that contains at least CD40 (a cell surface receptor of the tumour necrosis factor receptor (TNFR) superfamily), and other signaling molecules.


mitochondrial prohibitin complex

description: A complex composed of two proteins, prohibitin 1 and prohibitin 2 (PHB1/PHB-1 and PHB2/PHB-2) that is highly conserved amongst eukaryotes and associated with the inner mitochondrial membrane. The mitochondrial prohibitin complex is a macromolecular supercomplex composed of repeating heterodimeric subunits of PHB1 and PHB2. The mitochondrial prohibitin complex plays a role in a number of biological processes, including mitochondrial biogenesis and function, development, replicative senescence, and cell death.


maintenance of blood-brain barrier

description: Maintaining the structure and function of the blood-brain barrier, thus ensuring specific regulated transport of substances (e.g. macromolecules, small molecules, ions) into the brain, and out of the brain into the blood circulation.


response to stilbenoid

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of exposure to a stilbenoid. Stilbenoids are secondary products of heartwood formation in trees that can act as phytoalexins. Stilbenoids are hydroxylated derivatives of stilbene. They belong to the family of phenylpropanoids and share most of their biosynthesis pathway with chalcones.


entry of bacterium into host cell

description: The process in which a bacterium enters a host cell. The host is defined as the larger of the organisms involved in a symbiotic interaction.


name: purine ribonucleoside triphosphate binding

description: Binding to a purine ribonucleoside triphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with triphosphate on the sugar.


exploration behavior

description: The specific behavior of an organism in response to a novel environment or stimulus.


locomotory exploration behavior

description: The specific movement from place to place of an organism in response to a novel environment.


name: histone H3R17 methyltransferase activity

description: Catalysis of the reaction: S-adenosyl-L-methionine + (histone H3)-arginine (position 17) = S-adenosyl-L-homocysteine + (histone H3)-N-methyl-arginine (position 17). This reaction is the addition of a methyl group to the arginine residue at position 17 of histone H3.


L-DOPA receptor activity

description: Combining with L-DOPA to initiate a change in cell activity. L-DOPA is the modified amino acid (2S)-2-amino-3-(3,4-dihydroxyphenyl) propanoic acid, and is the precursor to dopamine, norepinephrine (noradrenaline) and epinephrine.


phosphoanandamide dephosphorylation

description: The process of removing one or more phosphate groups from a phosphorylated anandamide.


name: enteric smooth muscle cell differentiation

description: The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell of the intestine.


endosome to melanosome transport

description: The directed movement of substances from endosomes to the melanosome, a specialised lysosome-related organelle.


circadian mating behavior

description: The fluctuation in mating behavior that occurs over an approximately 24 hour cycle.


Nrd1 complex

description: A complex that functions in transcription termination of RNA polymerase II transcribed non-coding RNAs. This complex interacts with the carboxy-terminal domain (CTD) of PolII and the terminator sequences in the nascent RNA transcript. In yeast this complex consists of Nrd1p, Nab3p, and Sen1p.


AP-1 adaptor complex binding

description: Binding to an AP-1 adaptor complex. The AP-1 adaptor complex is a heterotetrameric AP-type membrane coat adaptor complex that consists of beta1, gamma, mu1 and sigma1 subunits and links clathrin to the membrane surface of a vesicle. In at least humans, the AP-1 complex can be heterogeneric due to the existence of multiple subunit isoforms encoded by different genes (gamma1 and gamma2, mu1A and mu1B, and sigma1A, sigma1B and sigma1C).


AP-3 adaptor complex binding

description: Binding to an AP-3 adaptor complex. The AP-3 adaptor complex is a heterotetrameric AP-type membrane coat adaptor complex that consists of beta3, delta, mu3 and sigma3 subunits and is found associated with endosomal membranes. In at least humans, the AP-3 complex can be heterogeneric due to the existence of multiple subunit isoforms encoded by different genes (beta3A and beta3B, mu3A and mu3B, and sigma3A and sigma3B).


clathrin-coated vesicle cargo loading

description: Formation of a macromolecular complex between the cytoplasmic coat proteins on clathrin-coated vesicles and proteins and/or lipoproteins that are going to be transported by a vesicle.


name: clathrin-coated vesicle cargo loading, AP-1-mediated

description: Formation of a macromolecular complex between proteins of the AP-1 adaptor complex and proteins and/or lipoproteins that are going to be transported by a clathrin-coated vesicle. The AP-1 adaptor protein complex is a component of the cytoplasmic coat found on clathrin-coated vesicles, and binds to sorting signals of cargo to facilitate their trafficking.


name: clathrin-coated vesicle cargo loading, AP-3-mediated

description: Formation of a macromolecular complex between proteins of the AP-3 adaptor complex and proteins and/or lipoproteins that are going to be transported by a clathrin-coated vesicle. In some cases, the AP-3 complex is a heterotetrameric AP-type membrane coat adaptor complex that, in some organisms, links clathrin to the membrane surface of a vesicle.


description: The series of molecular signals initiated by interleukin-18 binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.


eRF1 methyltransferase complex

description: A protein complex required for the methylation of a glutamine (Gln) residue in the protein release factor eRF1. In S. cerevisiae, this complex consists of at least Trm112p and Mtq2p.


Mon1-Ccz1 complex

description: A protein complex that functions as a guanine nucleotide exchange factor (GEF) and converts Rab-GDP to Rab-GTP. In S. cerevisiae, this complex consists of at least Mon1 and Ccz1, and serves as a GEF for the Rab Ypt7p.


name: MyD88-dependent toll-like receptor 4 signaling pathway

description: The series of molecular signals initiated by a ligand binding to a toll-like 4 receptor, where the MyD88 adaptor molecule mediates transduction of the signal. Toll-like 4 receptors bind bacterial lipopolysaccharide (LPS) to initiate an innate immune response.


name: MyD88-dependent toll-like receptor 2 signaling pathway

description: The series of molecular signals initiated by a ligand binding to a toll-like 2 receptor where the MyD88 adaptor molecule mediates transduction of the signal. Toll-like 2 receptors are pattern recognition receptors that bind microbial pattern motifs to initiate an innate immune response.


Toll-like receptor 4 binding

description: Binding to a Toll-like 4 protein, a pattern recognition receptor that binds bacterial lipopolysaccharide (LPS) to initiate an innate immune response.


Toll-like receptor 2 binding

description: Binding to a Toll-like 2 protein, a pattern recognition receptor that binds microbial pattern motifs to initiate an innate immune response.


name: TIRAP-dependent toll-like receptor signaling pathway

description: The series of molecular signals initiated by a ligand binding to a toll-like receptor where the TIRAP/MAL adaptor mediates transduction of the signal. Toll-like receptors directly bind pattern motifs from a variety of microbial sources to initiate an innate immune response.


name: TIRAP-dependent toll-like receptor 4 signaling pathway

description: The series of molecular signals initiated by a ligand binding to a toll-like receptor 4 where the TIRAP/MAL adaptor mediates transduction of the signal. Toll-like 4 receptors are pattern recognition receptors that bind bacterial lipopolysaccharide (LPS) to initiate an innate immune response.


name: TRIF-dependent toll-like receptor signaling pathway

description: The series of molecular signals initiated by a ligand binding to a toll-like receptor where the TRIF adaptor mediates transduction of the signal. Toll-like receptors directly bind pattern motifs from a variety of microbial sources to initiate an innate immune response.


name: TRIF-dependent toll-like receptor 4 signaling pathway

description: The series of molecular signals initiated by a ligand binding to a toll-like 4 receptor where the TRIF adaptor mediates transduction of the signal. Toll-like 4 receptors are pattern recognition receptors that bind bacterial lipopolysaccharide (LPS) to initiate an innate immune response.


name: TRAM-dependent toll-like receptor signaling pathway

description: The series of molecular signals initiated by a ligand binding to a toll-like receptor where the TRAM adaptor mediates transduction of the signal. Toll-like receptors directly bind pattern motifs from a variety of microbial sources to initiate an innate immune response.


name: TRAM-dependent toll-like receptor 4 signaling pathway

description: The series of molecular signals initiated by a ligand binding to a toll-like receptor 4 where the TRAM adaptor mediates transduction of the signal. Toll-like 4 receptors are pattern recognition receptors that bind bacterial lipopolysaccharide (LPS) to initiate an innate immune response.


plant-type ovary development

description: The process whose specific outcome is the progression of an ovary that produces an ovule over time, from its formation to the mature structure. The ovary is the enlarged basal portion of a carpel and matures into a fruit. An ovule is the multicellular structure that gives rise to and contains the female reproductive cells, and develops into a seed.


enone reductase activity

description: Catalysis of the reaction: an enone + NADPH + H+ = a ketone + NADP+.


oligopeptide transmembrane transport

description: The process in which an oligopeptide is transported across a membrane. Oligopeptides are molecules that contain a small number (2 to 20) of amino-acid residues connected by peptide linkages.


name: oligopeptide transmembrane transporter activity

description: Enables the transfer of oligopeptides from one side of a membrane to the other. Oligopeptides are molecules that contain a small number (2 to 20) of amino-acid residues connected by peptide linkages.


name: tricarboxylic acid transmembrane transport

description: The process in which a tricarboxylic acid is transported across a membrane.


neuromast hair cell development

description: The process whose specific outcome is the progression of a neuromast hair cell over time, from its formation to the mature structure. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. Cell development does not include the steps involved in committing a cell to a specific fate.


name: anterior lateral line neuromast hair cell development

description: The process whose specific outcome is the progression of an anterior lateral line neuromast hair cell over time, from its formation to the mature structure. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. Cell development does not include the steps involved in committing a cell to a specific fate.


name: posterior lateral line neuromast hair cell development

description: The process whose specific outcome is the progression of a posterior lateral line neuromast hair cell over time, from its formation to the mature structure. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. Cell development does not include the steps involved in committing a cell to a specific fate.


neuromast hair cell morphogenesis

description: The change in form (cell shape and size) that occurs when a neuromast hair cell progresses from its initial formation to its mature state. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface.


name: anterior lateral line neuromast hair cell morphogenesis

description: The change in form (cell shape and size) that occurs when an anterior lateral line neuromast hair cell progresses from its initial formation to its mature state. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface.


name: posterior lateral line neuromast hair cell morphogenesis

description: The change in form (cell shape and size) that occurs when a posterior lateral line neuromast hair cell progresses from its initial formation to its mature state. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface.


toll-like receptor 15 signaling pathway

description: The series of molecular signals initiated by a ligand binding to toll-like receptor 15.


toll-like receptor 21 signaling pathway

description: The series of molecular signals initiated by a ligand binding to toll-like receptor 21.


memory T cell extravasation

description: The migration of a memory T cell from the blood vessels into the surrounding tissue. A memory T cell is a distinctly differentiated long-lived T cell that has the phenotype CD45RO-positive and CD127-positive.


helper T cell extravasation

description: The migration of a helper T cell from the blood vessels into the surrounding tissue. A helper T-cell is an effector T cell that provides help in the form of secreted cytokines to other immune cells.


helper T cell diapedesis

description: The passage of a helper T cell between the tight junctions of endothelial cells lining blood vessels, typically the fourth and final step of cellular extravasation.


sperm fibrous sheath

description: A cytoskeletal structure surrounding the axoneme and outer dense fibers of the sperm flagellum. Consists of two longitudinal columns connected by closely arrayed semicircular ribs that assemble from distal to proximal throughout spermiogenesis. The fibrous sheath probably influences the degree of flexibility, plane of flagellar motion, and the shape of the flagellar beat.


T-helper 1 cell extravasation

description: The migration of a T-helper 1 cell from the blood vessels into the surrounding tissue. A T-helper 1 cell is a CD4-positive, alpha-beta T cell that has the phenotype T-bet-positive and produces interferon-gamma.


T-helper 1 cell diapedesis

description: The passage of a T-helper 1 cell between the tight junctions of endothelial cells lining blood vessels, typically the fourth and final step of cellular extravasation. A T-helper 1 cell is a CD4-positive, alpha-beta T cell that has the phenotype T-bet-positive and produces interferon-gamma.


name: chemokine (C-C motif) ligand 5 signaling pathway

description: The series of molecular signals initiated by chemokine CCL5 binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.


name: macrophage migration inhibitory factor signaling pathway

description: The series of molecular signals initiated by macrophage migration inhibitory factor binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.


name: macrophage migration inhibitory factor receptor complex

description: A protein complex that binds macrophage migration inhibitory factor. Comprises CD74 and CD44 cell surface proteins.


NOS2-CD74 complex

description: A protein complex comprising nitric oxide synthase 2 and CD74. This stable complex formation is thought to prevent CD74 degradation by caspases.


mitochondrial protein catabolic process

description: The chemical reactions and pathways resulting in the breakdown of a mitochondrial protein. This process is necessary to maintain the healthy state of mitochondria and is thought to occur via the induction of an intramitochondrial lysosome-like organelle that acts to eliminate the damaged oxidised mitochondrial proteins without destroying the mitochondrial structure.


mitophagy by internal vacuole formation

description: The process in which cells degrade mitochondria by inducing a vacuole-like structure which directly engulfs and degrades the unhealthy mitochondria by accumulating lysosomes.


monocyte extravasation

description: The migration of a monocyte from the blood vessels into the surrounding tissue.


name: CD8-positive, alpha-beta T cell extravasation

description: The migration of a CD8-positive, alpha-beta T cell from the blood vessels into the surrounding tissue.


name: CD8-positive, alpha-beta cytotoxic T cell extravasation

description: The migration of a CD8-positive, alpha-beta cytotoxic T cell from the blood vessels into the surrounding tissue.


T-helper 17 cell extravasation

description: The migration of a T-helper 17 cell from the blood vessels into the surrounding tissue.


astrocyte chemotaxis

description: The directed movement of an astrocyte guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).


hematopoietic stem cell migration

description: The orderly movement of a hematopoietic stem cell from one site to another. A hematopoietic stem cell is a cell from which all cells of the lymphoid and myeloid lineages develop, including blood cells and cells of the immune system.


monocyte homeostasis

description: The process of regulating the proliferation and elimination of monocytes such that the total number of monocytes within a whole or part of an organism is stable over time in the absence of an outside stimulus.


monocyte migration into blood stream

description: The movement of a monocyte from the bone marrow to the blood stream.


helper T cell chemotaxis

description: The directed movement of a helper T cell in response to an external stimulus.


T-helper 17 cell chemotaxis

description: The directed movement of a T-helper 17 cell in response to an external stimulus.


T-helper 1 cell chemotaxis

description: The directed movement of a T-helper 1 cell in response to an external stimulus.


T-helper 2 cell chemotaxis

description: The directed movement of a T-helper 2 cell in response to an external stimulus.


name: interleukin-4-dependent isotype switching to IgE isotypes

description: The switching of activated B cells from IgM biosynthesis to IgE biosynthesis, accomplished through a recombination process involving an intrachromosomal deletion between switch regions that reside 5' of the IgM and IgE constant region gene segments in the immunoglobulin heavy chain locus, that is dependent on the activity of interleukin 4 (IL-4).


memory T cell activation

description: The change in morphology and behavior of a memory T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.


name: CD4-positive, alpha-beta T cell activation

description: The change in morphology and behavior of a CD4-positive, alpha-beta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.


T-helper 1 cell activation

description: The change in morphology and behavior of a T-helper 1 cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.


T-helper 2 cell activation

description: The change in morphology and behavior of a T helper 2 cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.


response to nitrogen dioxide

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrogen dioxide (NO2) stimulus.


cellular response to nitrogen dioxide

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrogen dioxide (NO2) stimulus.


chemokine (C-C motif) ligand 2 binding

description: Binding to chemokine (C-C motif) ligand 2.


chemokine (C-C motif) ligand 12 binding

description: Binding to chemokine (C-C motif) ligand 12.


chemokine (C-C motif) ligand 7 binding

description: Binding to chemokine (C-C motif) ligand 7.


name: macrophage migration inhibitory factor binding

description: Binding to the cytokine, macrophage migration inhibitory factor.


tRNA import into nucleus

description: The directed movement of tRNA from the cytoplasm to the nucleus.


intraciliary anterograde transport

description: The directed movement of large protein complexes along microtubules from the cell body toward the tip of a cilium (also called flagellum), mediated by motor proteins.


intraciliary retrograde transport

description: The directed movement of large protein complexes along microtubules from the tip of a cilium (also called flagellum) toward the cell body, mediated by motor proteins.


description: The series of molecular signals initiated by interleukin-12 binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.


description: The series of molecular signals initiated by interleukin-15 binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.


CD24 biosynthetic process

description: The chemical reactions and pathways resulting in the formation of CD24, a CD marker and cell adhesion molecule that occurs on many B-lineage cells and mature granulocytes, and is involved in B cell activation and differentiation as well as T cell co-stimulation.


sodium ion transmembrane transport

description: A process in which a sodium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.


name: common myeloid progenitor cell proliferation

description: The multiplication or reproduction of common myeloid progenitor cells, resulting in the expansion of a cell population. A common myeloid progenitor cell is a progenitor cell committed to the myeloid lineage.


lysophosphatidic acid binding

description: Binding to lysophosphatidic acid (LPA), a phospholipid derivative that acts as a potent mitogen due to its activation of high-affinity G protein-coupled receptors.


response to hepatocyte growth factor

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hepatocyte growth factor stimulus.


name: cellular response to hepatocyte growth factor stimulus

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hepatocyte growth factor stimulus.


S-nitrosoglutathione binding

description: Binding to S-nitrosoglutathione, a nitrosothiol considered to be a natural nitric oxide (NO) donor involved in S-nitrosylation, and in the storage and transport of nitric oxide in biological systems.


dinitrosyl-iron complex binding

description: Binding to a dinitrosyl-iron complex. Nitric oxide (NO) is stored as dinitrosyl-iron complexes, which form spontaneously from Glutathione (GSH), S-nitrosoglutathione, and trace amounts of ferrous ions, or by reaction of iron-sulfur centers with NO.


nitric oxide storage

description: The accumulation and maintenance in cells or tissues of nitric oxide (NO). Nitric oxide is stored in the form of dinitrosyl-iron complexes, which are stabilized, and possibly sequestered, by binding to glutathione S-transferase proteins.


hepatic stellate cell activation

description: A change in the morphology or behavior of a hepatic stellate cell resulting from exposure to a cytokine, chemokine, hormone, cellular ligand or soluble factor.


name: intraciliary transport involved in cilium assembly

description: The bidirectional movement of large protein complexes along microtubules within a cilium that contributes to cilium assembly.


name: cell proliferation involved in compound eye morphogenesis

description: The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to compound eye morphogenesis.


name: envenomation resulting in modulation of process in another organism

description: The process which begins with venom being forced into an organism by the bite or sting of another organism, and ends with the manifestation of some change or damage to the bitten organism.


name: CD4-positive, alpha-beta T cell proliferation

description: The expansion of a CD4-positive, alpha-beta T cell population by cell division.


name: CD8-positive, alpha-beta T cell proliferation

description: The expansion of a CD8-positive, alpha-beta T cell population by cell division.


name: activated CD4-positive, alpha-beta T cell proliferation

description: The expansion of an activated CD4-positive, alpha-beta T cell population by cell division.


name: activated CD8-positive, alpha-beta T cell proliferation

description: The expansion of an activated CD8-positive, alpha-beta T cell population by cell division.


name: CD4-positive, alpha-beta T cell cytokine production

description: Any process that contributes to cytokine production by a CD4-positive, alpha-beta T cell.


T-helper 1 cell cytokine production

description: Any process that contributes to cytokine production by a T-helper 1 cell.


T-helper 2 cell cytokine production

description: Any process that contributes to cytokine production by a T-helper 2 cell.


granzyme A production

description: The appearance of granzyme A due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


natural killer cell chemotaxis

description: The directed movement of a natural killer cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).


myelin sheath abaxonal region

description: The region of the myelin sheath furthest from the axon.


myelin sheath adaxonal region

description: The region of the myelin sheath nearest to the axon.


name: protein localization to myelin sheath abaxonal region

description: Any process in which a protein is transported to, and/or maintained in, the abaxonal region of the myelin sheath. The abaxonal region is the region of the myelin sheath furthest from the axon.


regulation of lysosomal lumen pH

description: Any process that modulates the pH of the lysosomal lumen, measured by the concentration of the hydrogen ion.


lysosomal lumen pH elevation

description: Any process that increases the pH of the lysosomal lumen, measured by the concentration of the hydrogen ion.


name: maintenance of DNA trinucleotide repeats

description: Any process involved in sustaining the fidelity and copy number of DNA trinucleotide repeats. DNA trinucleotide repeats are naturally occurring runs of three base-pairs.


B cell chemotaxis

description: The directed movement of a B cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).


cardiolipin hydrolase activity

description: Catalysis of the hydrolysis of cardiolipin (1,3-bis(3-phosphatidyl)glycerol), releasing phosphatidic acid (PA).


name: symbiont-mediated migration through host transepithelium

description: A process in which a symbiont moves from one side of an epithelium to the other within its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.


chemokine (C-C motif) ligand 19 binding

description: Binding to chemokine (C-C motif) ligand 19.


chemokine (C-C motif) ligand 21 binding

description: Binding to chemokine (C-C motif) ligand 21.


mesangial cell-matrix adhesion

description: The binding of a mesangial cell to the extracellular matrix via adhesion molecules. A mesangial cell is a cell that encapsulates the capillaries and venules in the kidney.


name: cytoplasmic polyadenylation-dependent rRNA catabolic process

description: The chemical reactions and pathways occurring in the cytoplasm and resulting in the breakdown of a ribosomal RNA (rRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target rRNA truncated degradation intermediate.


name: dorsal motor nucleus of vagus nerve maturation

description: A developmental process, independent of morphogenetic (shape) change, that is required for the dorsal motor nucleus of the vagus nerve to attain its fully functional state.


name: dorsal motor nucleus of vagus nerve morphogenesis

description: The process in which the dorsal motor nucleus of the vagus nerve is generated and organized. Morphogenesis pertains to the creation of form.


name: dorsal motor nucleus of vagus nerve structural organization

description: The process that contributes to the act of creating the structural organization of the dorsal motor nucleus of the vagus nerve. This process pertains to the physical shaping of a rudimentary structure.


name: dorsal motor nucleus of vagus nerve formation

description: The process that gives rise to the dorsal motor nucleus of the vagus nerve. This process pertains to the initial formation of a structure from unspecified parts.


name: motor neuron precursor migration involved in dorsal motor nucleus of vagus nerve formation

description: The orderly movement of a motor neuron precursor cell that contributes to formation of the dorsal motor nucleus of the vagus nerve.


name: cell chemotaxis to fibroblast growth factor

description: The directed movement of a motile cell in response to the presence of fibroblast growth factor (FGF).


endothelial cell chemotaxis

description: The directed movement of an endothelial cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).


name: endothelial cell chemotaxis to fibroblast growth factor

description: The directed movement of an endothelial cell in response to the presence of fibroblast growth factor (FGF).


name: B cell chemotaxis across high endothelial venule

description: The movement of a B cell to cross a high endothelial venule in response to an external stimulus.


ribonucleoprotein granule

description: A non-membranous macromolecular complex containing proteins and translationally silenced mRNAs. RNA granules contain proteins that control the localization, stability, and translation of their RNA cargo. Different types of RNA granules (RGs) exist, depending on the cell type and cellular conditions.


description: The series of molecular signals initiated by interleukin-4 binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.


description: The series of molecular signals initiated by interleukin-13 binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.


name: insulin secretion involved in cellular response to glucose stimulus

description: The regulated release of proinsulin from secretory granules (B granules) in the B cells of the pancreas; accompanied by cleavage of proinsulin to form mature insulin, in response to a glucose stimulus.


name: positive regulation of insulin secretion involved in cellular response to glucose stimulus

description: Any process that increases the frequency, rate or extent of the regulated release of insulin that contributes to the response of a cell to glucose.


pronephric glomerulus morphogenesis

description: The process in which the anatomical structures of the pronephric glomerulus are generated and organized. The pronephric glomerulus is part of the pronephric nephron and is restricted to one body segment.


pronephric proximal tubule development

description: The progression of the pronephric proximal tubule over time, from its formation to the mature structure. A pronephric nephron tubule is an epithelial tube that is part of the pronephros.


pronephric distal tubule development

description: The process whose specific outcome is the progression of the pronephric distal tubule over time, from its formation to the mature structure. A pronephric nephron tubule is an epithelial tube that is part of the pronephros.


name: pronephric nephron tubule epithelial cell differentiation

description: The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the pronephric nephron tubule as it progresses from its formation to the mature state.


angioblast cell differentiation

description: The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of an angioblast cell. Angioblasts are one of the two products formed from hemangioblast cells (the other being pluripotent hemopoietic stem cells).


CD80 biosynthetic process

description: The chemical reactions and pathways resulting in the formation of CD80, a CD marker that occurs on antigen presenting cells such as activated B cells and monocytes that provides a co-stimulatory signal necessary for T cell activation and survival.


CD86 biosynthetic process

description: The chemical reactions and pathways resulting in the formation of CD86, a CD marker that occurs on antigen presenting cells that provides co-stimulatory signals necessary for T cell activation and survival.


mature natural killer cell chemotaxis

description: The directed movement of a mature natural killer cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis). A mature natural killer cell is a natural killer cell that is developmentally mature and expresses a variety of inhibitory and activating receptors that recognize MHC class and other stress related molecules.


name: CD4-positive, alpha-beta T cell costimulation

description: The process of providing, via surface-bound receptor-ligand pairs, a second, antigen-independent, signal in addition to that provided by the T cell receptor to augment CD4-positive, alpha-beta T cell activation.


intracellular nickel ion homeostasis

description: A homeostatic process involved in the maintenance of a steady state level of nickel ions within a cell.


name: cell migration involved in kidney development

description: The orderly movement of a cell from one site to another that will contribute to the progression of the kidney over time, from its formation to the mature organ.


name: cell migration involved in metanephros development

description: The orderly movement of a cell from one site to another that will contribute to the progression of the metanephric kidney over time, from its formation to the mature organ.


metanephric mesenchymal cell migration

description: The orderly movement of undifferentiated metanephric mesenchymal cells (precursors to metanephric mesangial cells) from the mesenchyme into the cleft of the developing glomerulus, during development of the metanephros.


name: platelet-derived growth factor receptor-alpha signaling pathway

description: The series of molecular signals initiated a ligand binding to an alpha-type platelet-derived growth factor receptor (PDGFalpha) on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.


name: platelet-derived growth factor receptor-beta signaling pathway

description: The series of molecular signals initiated by the binding of a ligand to a beta-type platelet-derived growth factor receptor (PDGFbeta) on the surface of a signal-receiving cell, and ending with the regulation of a downstream cellular process, e.g. transcription.


host cell postsynaptic membrane

description: A postsynaptic membrane that is part of a host cell. A postsynaptic membrane is a specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft). Neurotransmitters transmit the signal across the synaptic cleft to the postsynaptic membrane.


name: positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway

description: Any process that increases the frequency, rate or extent of metanephric mesenchymal cell migration resulting from the platelet-derived growth factor receptor-beta signaling pathway.


name: positive regulation of mitochondrial membrane permeability

description: Any process that increases the frequency, rate or extent of the passage or uptake of molecules by the mitochondrial membrane.


name: negative regulation of mitochondrial membrane permeability

description: Any process that decreases the frequency, rate or extent of the passage or uptake of molecules by the mitochondrial membrane.


name: ATP-binding cassette (ABC) transporter complex, transmembrane substrate-binding subunit-containing

description: A complex for the transport of metabolites into the cell, consisting of 4 subunits: a transmembrane substrate-binding protein (known as the S component), and an energy-coupling module that comprises two ATP-binding proteins (known as the A and A' components) and a transmembrane protein (known as the T component). Transport of the substrate across the membrane is driven by the hydrolysis of ATP.


tellurite methyltransferase activity

description: Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to tellurite [TeO3(2-)]. Methylated derivatives of tellurite include Te(CH3)2 (dimethyltelluride) and Te2(CH3)2 (dimethylditelluride).


2-alkenal reductase (NADPH) activity

description: Catalysis of the reaction: n-alkanal + NADP+ = alk-2-enal + NADPH + H+.


ureter maturation

description: A developmental process, independent of morphogenetic (shape) change, that is required for the ureter to attain its fully functional state. The ureter is a muscular tube that transports urine from the kidney to the urinary bladder or from the Malpighian tubule to the hindgut.


deubiquitinase activator activity

description: Binds to and increases the activity of a deubiquitinase.


adrenal cortex development

description: The process whose specific outcome is the progression of the adrenal cortex over time, from its formation to the mature structure. The adrenal cortex is located at the periphery of the adrenal gland and controls glucose and electrolyte metabolism, response to stress and sexual development through the production of different classes of steroid hormones (glucocorticoids, mineralocorticoids and androgens).


adrenal cortex formation

description: The process that gives rise to the adrenal cortex. This process pertains to the initial formation of a structure from unspecified parts. The adrenogonadal primordium from which the adrenal cortex is formed derives from a condensation of coelomic epithelial cells (the urogenital ridge; the same structure from which gonads and kidney also originate).


egg coat formation

description: Construction of an egg coat, a specialized extracellular matrix that surrounds the ovum of animals. The egg coat provides structural support and can play an essential role in oogenesis, fertilization and early development.


structural constituent of egg coat

description: The action of a molecule that contributes to the structural integrity of an egg coat. An egg coat is a specialized extracellular matrix that surrounds the ovum of animals. The egg coat provides structural support and can play an essential role in oogenesis, fertilization and early development.


egg coat

description: A specialized extracellular matrix that surrounds the plasma membrane of the ovum of animals. The egg coat provides structural support and can play an essential role in oogenesis, fertilization and early development.


name: perturbation of blood coagulation in another organism

description: The process in which an organism effects a change that affects blood coagulation in another organism. Blood coagulation is the sequential process in which the multiple coagulation factors of the blood interact, ultimately resulting in the formation of an insoluble fibrin clot.