myosin III binding

description: Binding to a class III myosin; myosin III is monomeric and has an N terminal kinase domain.


myosin IV complex

category: biolink:CellularComponent biolink:AnatomicalEntity biolink:PhysicalEssence biolink:OrganismalEntity biolink:SubjectOfInvestigation biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: A myosin complex containing one or more class IV myosin heavy chains and associated light chains; myosin IV is relatively uncharacterized, but is predicted to have a single motor domain, one IQ motif and a tail with a Myosin Tail Homology (myTH4) domain homologous to that in the tails of myosins VII and XV.


myosin V complex

description: A myosin complex containing a dimer of class V myosin heavy chains and associated light chains; involved in intracellular transport. Myosin V is a dimeric molecule consisting of conserved motor domains followed by 6 IQ motifs which bind specific light chains and calmodulin. The tail domain is important for cellular localization and cargo binding and can be divided into an alpha-helical coiled coil region and a C-terminal globular region.


myosin VI complex

description: A myosin complex containing one or more class VI myosin heavy chains and associated light chains. Myosin VI has a single IQ motif in the neck and a tail region with a coiled coil domain followed by a unique globular domain; a unique insertion that enables myosin VI to move towards the pointed or minus end of actin filaments.


myosin VII complex

description: A myosin complex containing a dimer of class VII myosin heavy chains and associated light chains. Myosin VII (240 kDa) is predicted to be a dimeric molecule with 5 IQ motifs and a tail region with a short stretch of coiled coil followed by two myosin-tail homology (MyTH4) domains, two talin-binding (FERM) domains and an SH3-domain.


myosin VIII complex

description: A myosin complex containing a dimer of class VIII myosin heavy chains and associated light chains. Myosin VIII is predicted to be dimeric, and contain an unusual 100-190 residue N-terminal extension prior to their motor domains, 3-4 IQ motifs, a short region (~70 residues) of predicted alpha-helical coiled coil and a C-terminal domain.


myosin IX complex

description: A myosin complex containing a class IX myosin heavy chain and associated light chains. Myosin IX is monomeric with a motor domain containing an N-terminal extension and an insert in the actin binding interface, followed by four to six IQ motifs and a tail region that contains a zinc binding motif and a domain with homology to GTPase activating proteins (GAPs) of the Rho family of G-proteins.


myosin X complex

description: A myosin complex containing one or more class X myosin heavy chains and associated light chains.


myosin XI complex

description: A myosin complex containing a dimer of class XI myosin heavy chains and associated light chains. Myosin XI heavy chain sizes are similar in molecular structure to the class V myosins with 5 to 6 IQ motifs and tail regions with predicted coiled coil domains (forming dimeric molecules) and large C-terminal regions.


myosin XII complex

description: A myosin complex containing one or more class XII myosin heavy chains and associated light chains; myosin XII contains a large tail region with two MyTH4 domains and a short region of coiled coil.


myosin XIII complex

description: A myosin complex containing one or more class XIII myosin heavy chains and associated light chains.


myosin XIV complex

description: A myosin complex containing a class XIV myosin heavy chain and associated light chains; myosin XIV heavy chains are the simplest known, containing a motor domain, no classic IQ motif and variable length tails.


myosin XV complex

description: A myosin complex containing a class XV myosin heavy chain and associated light chains. Myosin XV is single headed, and has a large extension (1200aa) at the N-terminus of the motor domain, two IQ motifs and a tail with a similar domain structure to that of the tail of myosin VII.


myosin XVI complex

description: A myosin complex containing a class XVI myosin heavy chains and associated light chains; myosin XVI heavy chains contain ankyrin repeat.


myosin XVII complex

description: A myosin complex containing one or more class XVII myosin heavy chains and associated light chains.


myosin XVIII complex

description: A myosin complex containing a class XVIII myosin heavy chain and associated light chains; myosin XVIII heavy chains contain an N-terminal PDZ domain.


myosin V binding

category: biolink:MolecularActivity biolink:Occurrent biolink:OntologyClass biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: Binding to a class V myosin; myosin V is a dimeric molecule involved in intracellular transport.


chromatin DNA binding

description: Binding to DNA that is assembled into chromatin.


nucleosome binding

description: Binding to a nucleosome, a complex comprised of DNA wound around a multisubunit core and associated proteins, which forms the primary packing unit of DNA into higher order structures.


nucleosomal DNA binding

description: Binding to the DNA portion of a nucleosome.


regulation of mating type switching

category: biolink:BiologicalProcess biolink:Occurrent biolink:OntologyClass biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: Any process that modulates the frequency, rate or extent of mating type switching, the conversion of a single-cell organism from one mating type to another by the precise replacement of a DNA sequence at the expressed mating type locus with a copy of a sequence from a donor locus.


name: negative regulation of mating type switching

description: Any process that stops, prevents, or reduces the frequency, rate or extent of mating type switching.


name: positive regulation of mating type switching

description: Any process that activates or increases the frequency, rate or extent of mating type switching.


TRAMP complex

description: A multiprotein complex having distributive polyadenylation activity of a variety of RNA substrates including hypomodified and incorrectly folded tRNAs, pre-snRNAs, pre-snoRNAs, incorrectly spliced or processed pre-mRNAs, cryptic unstable transcripts (CUTs), pre-rRNAs and rRNA fragments released as part of rRNA processing. In S. cerevisiae, the complex consists of either Pap2 (also known as Trf4) or Trf5, Air1 or Air2, and Mtr4, and is involved in RNA 3'-end processing and in RNA surveillance and quality control.


Tea1 cell-end complex

description: A high molecular weight complex characterized in S. pombe containing the cell-end anchoring protein Tea1. This complex is transported to the cell ends by microtubules and is involved in bipolar growth and the maintennce of normal cell polarity.


mannosyltransferase complex

description: A complex that possesses mannosyltransferase activity.


description: A complex that possesses dolichyl-phosphate-mannose-protein mannosyltransferase activity; usually includes members of the PMT1 and PMT2 protein subfamilies.


protein-containing complex localization

description: A localization process that acts on a protein complex; the complex is transported to, or maintained in, a specific location.


name: peptidoglycan-based cell wall organization

description: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the peptidoglycan-based cell wall.


fungal-type cell wall organization

description: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the fungal-type cell wall.


name: cell wall glycoprotein biosynthetic process

description: The chemical reactions and pathways resulting in the formation of cell wall glycoproteins, any cell wall protein that contains covalently bound sugar residues.


heterochromatin formation

description: An epigenetic gene silencing mechanism in which chromatin is compacted into heterochromatin, resulting in a chromatin conformation refractory to transcription. This process starts with heterochromatin nucleation, its spreading, and ends with heterochromatin boundary formation.


pericentric heterochromatin formation

description: The compaction of chromatin located adjacent to the CENP-A rich centromere 'central core' and characterized by methylation of histone H3K9, into heterochromatin, resulting in the repression of transcription at pericentric DNA.


subtelomeric heterochromatin formation

description: The compaction of chromatin into heterochromatin at the subtelomeric region.


SUMO activating enzyme complex

description: A conserved heterodimeric complex with SUMO activating enzyme activity.


Mis6-Sim4 complex

description: A protein complex that forms part of the inner kinetochore, which is involved in the loading of the centromeric histone h3 variant CENP-A onto centromeres and in centromere specific heterochromatin formation. The complex contains about 12 proteins, of which two are known as Mis6 and Sim4 in S. pombe and CENP-I and CENP-H in human.


motile cilium

description: A cilium which may have a variable arrangement of axonemal microtubules and also contains molecular motors. It may beat with a whip-like pattern that promotes cell motility or transport of fluids and other cells across a cell surface, such as on epithelial cells that line the lumenal ducts of various tissues; or they may display a distinct twirling motion that directs fluid flow asymmetrically across the cellular surface to affect asymmetric body plan organization. Motile cilia can be found in single as well as multiple copies per cell.


tRNA (m1A) methyltransferase complex

description: A protein complex involved in the catalysis of the formation of the modified nucleotide 1-methyladenosine (m1A) in tRNA. In yeast, it is a heterotetramer of two subunits, Gcd10p and Gcd14p, while in bacteria and archaea it is a homotetramer.


far-red light photoreceptor activity

description: The function of absorbing and responding to electromagnetic radiation with a wavelength of approximately 730nm. The response may involve a change in conformation.


red light photoreceptor activity

description: The function of absorbing and responding to electromagnetic radiation with a wavelength of approximately 660nm. The response may involve a change in conformation.


CBF3 complex

description: A multisubunit protein complex that binds to centromeric DNA and initiates kinetochore assembly. In yeast, this complex consists of four subunits, namely Ctf13p, Skp1p, Cep3p and Cbf2p.


PcG protein complex

description: A chromatin-associated multiprotein complex containing Polycomb Group proteins. In Drosophila, Polycomb group proteins are involved in the long-term maintenance of gene repression, and PcG protein complexes associate with Polycomb group response elements (PREs) in target genes to regulate higher-order chromatin structure.


plasma membrane of cell tip

description: The portion of the plasma membrane surrounding the cell tip.


spitzenkorper

description: Structure within the hyphal tip of filamentous fungi that acts as an organizing center for hyphal tip growth; may function to supply vesicles to the elongating tip and/or to organize cytoskeletal microfilaments.


name: cell envelope Sec protein transport complex

description: A transmembrane protein complex involved in the translocation of proteins across the cytoplasmic membrane. In Gram-negative bacteria, Sec-translocated proteins are subsequently secreted via the type II, IV, or V secretion systems. Sec complex components include SecA, D, E, F, G, Y and YajC.


Myb complex

description: A multisubunit complex consisting of Myb and other proteins that regulates site specific DNA replication, gene amplification and transcriptional repression.


menthol metabolic process

description: The chemical reactions and pathways involving menthol, the monoterpene 2-isopropyl-5-methylcyclohexanol.


menthol biosynthetic process

description: The chemical reactions and pathways resulting in the formation of menthol, the monoterpene 2-isopropyl-5-methylcyclohexanol.


brush border membrane

description: The portion of the plasma membrane surrounding the brush border.


filopodium membrane

description: The portion of the plasma membrane surrounding a filopodium.


microvillus membrane

description: The portion of the plasma membrane surrounding a microvillus.


ruffle organization

description: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a ruffle, a projection at the leading edge of a crawling cell.


name: gonadotropin-releasing hormone receptor binding

description: Binding to a receptor for gonadotropin-releasing hormone (GnRH), a peptide hormone that is synthesized and released by the hypothalamus and is responsible for the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the anterior pituitary.


name: thyrotropin-releasing hormone receptor binding

description: Binding to a receptor for thyrotropin-releasing hormone, a tripeptide hormone that is produced by the hypothalamus and stimulates the release of thyroid-stimulating hormone (TSH) and prolactin by the anterior pituitary.


mRNA capping enzyme complex

description: A protein complex that consists of an RNA 5' triphosphatase and a guanyl transferase (Cet1p and Ceg1p in S. cerevisiae; Pct1 and Ceg1 in S. pombe) and is involved in mRNA capping.


minus-end directed microtubule sliding

description: The movement of one microtubule along another microtubule, where the motion is directed towards the minus ends of the microtubules.


plus-end directed microtubule sliding

description: The movement of one microtubule along another microtubule, where the motion is directed towards the plus ends of the microtubules.


name: positive regulation of exit from mitosis

description: Any process that activates or increases the rate of progression from anaphase/telophase (high mitotic CDK activity) to G1 (low mitotic CDK activity).


name: regulation of anthocyanin metabolic process

description: Any process that modulates the frequency, rate or extent of chemical reactions and pathways involving anthocyanins.


name: negative regulation of anthocyanin metabolic process

description: Any process that stops, prevents, or reduces the frequency, rate or extent of chemical reactions and pathways involving anthocyanins.


name: positive regulation of anthocyanin metabolic process

description: Any process that activates or increases the frequency, rate or extent of chemical reactions and pathways involving anthocyanins.


name: regulation of anthocyanin biosynthetic process

description: Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of anthocyanins.


name: negative regulation of anthocyanin biosynthetic process

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of anthocyanins.


name: positive regulation of anthocyanin biosynthetic process

description: Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of anthocyanins.


peptidyl-proline dioxygenase activity

description: Catalysis of the reaction: peptidyl L-proline + 2-oxoglutarate + O2 = peptidyl hydroxy-L-proline + succinate + CO2.


peptidyl-proline 3-dioxygenase activity

description: Catalysis of the reaction: peptidyl L-proline + 2-oxoglutarate + O2 = peptidyl trans-3-hydroxy-L-proline + succinate + CO2.


peptidyl-proline 4-dioxygenase activity

description: Catalysis of the reaction: peptidyl L-proline + 2-oxoglutarate + O2 = peptidyl trans-4-hydroxy-L-proline + succinate + CO2.


name: brain-derived neurotrophic factor receptor binding

description: Binding to a brain-derived neurotrophic factor receptor.


name: brain-derived neurotrophic factor receptor signaling pathway

category: biolink:Pathway biolink:OntologyClass biolink:BiologicalProcess biolink:Occurrent biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: The series of molecular signals generated as a consequence of a brain-derived neurotrophic factor receptor binding to one of its physiological ligands.


name: regulation of brain-derived neurotrophic factor receptor signaling pathway

description: Any process that modulates the frequency, rate or extent of signaling via the brain-derived neurotrophic factor receptor signaling pathway.


name: negative regulation of brain-derived neurotrophic factor receptor signaling pathway

description: Any process that stops, prevents, or reduces the frequency, rate or extent of signaling via the brain-derived neurotrophic factor receptor signaling pathway.


name: positive regulation of brain-derived neurotrophic factor receptor signaling pathway

description: Any process that activates or increases the frequency, rate or extent of signaling via the brain-derived neurotrophic factor receptor signaling pathway.


name: regulation of brain-derived neurotrophic factor-activated receptor activity

description: Any process that modulates the frequency, rate or extent of brain-derived neurotrophic factor-activated receptor activity.


name: negative regulation of brain-derived neurotrophic factor-activated receptor activity

description: Any process that stops, prevents, or reduces the frequency, rate or extent of brain-derived neurotrophic factor-activated receptor activity.


name: positive regulation of brain-derived neurotrophic factor-activated receptor activity

description: Any process that activates or increases the frequency, rate or extent of brain-derived neurotrophic factor-activated receptor activity.


name: regulation of termination of DNA-templated transcription

description: Any process that modulates the frequency, rate, extent, or location of DNA-templated transcription termination, the process in which transcription is completed; the formation of phosphodiester bonds ceases, the RNA-DNA hybrid dissociates, and RNA polymerase releases the DNA.


transcriptional attenuation

description: A negative regulation of gene expression mechanism by which bacteria and archae can direct RNA polymerase to prematurely terminate transcription in response to a specific metabolic signal.


transcriptional attenuation by ribosome

description: A type of transcriptional regulation at the level of early termination. This process can occur only in prokaryotes, where transcription of an operon into messenger RNA and translation of that mRNA into polypeptides occur simultaneously. The general principle is that alternative mRNA secondary structures occur under different physiological conditions such as available amount of a particular amino acid. One set of conditions favors early termination of transcription. In the classic example of the trp biosynthesis operon, translation of the gene for a short, trp-containing polypeptide called the trp operon leader peptide pauses either at a trp codon (if tryptophan is scarce) or the stop codon (if trp is readily available). In the former situation transcription continues, but in the latter a Rho-independent terminator forms and reduces, or attenuates, expression of the tryptophan biosynthesis genes. Although the polypeptides encoded by leader peptide genes appear not to be stable once their translation is complete, it is suggested by recent studies that their nascent polypeptide chains interact specifically with ribosomes, specific uncharged tRNAs, or other cellular components to inhibit release at the stop codon and improve the function of transcriptional attenuation as a regulatory switch.


oxidosqualene cyclase activity

description: Catalysis of the cyclization of (S)-2,3-epoxysqualene to form a triterpene.


cellular bud neck polarisome

description: Protein complex that has a role in determining cell polarity, found at the neck of a fungal bud before and during cytokinesis.


cellular bud tip polarisome

description: Protein complex that has a role in determining cell polarity, found at the tip of a growing fungal bud.


hyphal tip polarisome

description: Protein complex that has a role in determining cell polarity, found at the tip of a growing fungal hypha.


mating projection tip polarisome

description: Protein complex that has a role in determining cell polarity, found at the tip of the mating projection in unicellular fungi exposed to mating pheromone.


transcription antitermination

description: A positive regulation of gene expression mechanism that allows RNA polymerase to continue transcription beyond a termination site, thus allowing expression of downstream genes under specific conditions.


actomyosin contractile ring maturation

description: The cellular process in which the contractile ring cytokinetic ring attains its fully functional state.


name: mitotic cell size control checkpoint signaling

description: A signal transduction process that contributes to a cell size control checkpoint during mitosis.


name: mitotic G1 cell size control checkpoint signaling

description: A signal transduction process that contributes to a cell size control checkpoint during the G1/S transition of the cell cycle.


name: mitotic G2 cell size control checkpoint signaling

description: A signal transduction process that contributes to a cell size control checkpoint prior to the G2/M transition of mitosis.


DNA integrity checkpoint signaling

description: A signaling process that controls cell cycle progression in response to changes in DNA structure by monitoring the integrity of the DNA. The DNA integrity checkpoint begins with detection of DNA damage, defects in DNA structure or DNA replication, and progresses through signal transduction and ends with cell cycle effector processes.


name: mitotic G1 DNA damage checkpoint signaling

description: A signal transduction process that contributes to a mitotic cell cycle G1/S transition DNA damage checkpoint.


name: mitotic intra-S DNA damage checkpoint signaling

description: A mitotic cell cycle checkpoint that slows DNA synthesis in response to DNA damage by the prevention of new origin firing and the stabilization of slow replication fork progression.


spindle checkpoint signaling

description: A signaling process that that controls a cell cycle checkpoint that originates from the mitotic or meiotic spindle.


name: mitotic spindle orientation checkpoint signaling

description: A signaling process that monitors and signals errors in the placement or orientation of the spindle in the cell. This delays the completion of anaphase until errors are corrected.


membrane raft organization

description: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of membrane rafts, small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes.


membrane raft distribution

description: The process that establishes the spatial arrangement of membrane rafts within a cellular membrane.


hemidesmosome assembly

description: Assembly of hemidesmosomes, integrin-containing protein complexes that bind to laminin in the basal lamina. Hemidesmosomes form the contact between the basal surface of epithelial cells and the underlying basal lamina.


replication fork arrest at rDNA repeats

description: A process that impedes the progress of the DNA replication fork at natural replication fork pausing sites within the eukaryotic rDNA repeat spacer.


name: phospholipase D-activating G protein-coupled receptor signaling pathway

description: A G protein-coupled receptor signaling pathway in which the signal is transmitted via the activation of phospholipase D (PLD) and a subsequent increase in the intracellular concentration of phosphatidic acid (PA).


activation of phospholipase D activity

description: Any process that initiates the activity of inactive phospholipase D.


name: regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity

description: Any process that modulates the frequency, rate or extent of the activity of the inositol 1,4,5-trisphosphate-sensitive calcium-release channel.


name: negative regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of the inositol 1,4,5-trisphosphate-sensitive calcium-release channel.


name: positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity

description: Any process that activates or increases the frequency, rate or extent of the activity of the inositol 1,4,5-trisphosphate-sensitive calcium-release channel.


name: nucleotide-activated protein kinase complex

description: A protein complex that possesses nucleotide-dependent protein kinase activity. The nucleotide can be AMP (in S. pombe and human) or ADP (in S. cerevisiae).


cell-substrate adhesion

description: The attachment of a cell to the underlying substrate via adhesion molecules.


wybutosine metabolic process

description: The chemical reactions and pathways involving wybutosine, 3H-imidazo[1,2-alpha]purine-7-butanoic acid, 4,9-dihydro- alpha-[(methoxycarbonyl)amino]- 4,6-dimethyl-9-oxo- 3-beta-D-ribofuranosyl methyl ester, a modified nucleoside found in some tRNA molecules.


wybutosine biosynthetic process

description: The chemical reactions and pathways resulting in the formation of wybutosine, 3H-imidazo[1,2-alpha]purine-7-butanoic acid, 4,9-dihydro- alpha-[(methoxycarbonyl)amino]- 4,6-dimethyl-9-oxo- 3-beta-D-ribofuranosyl methyl ester, a modified nucleoside found in some tRNA molecules.


centrosomal corona

description: An amorphous structure surrounding the core of the centrosome, from which microtubules are nucleated; contains gamma-tubulin.


name: polyubiquitin modification-dependent protein binding

description: Binding to a protein upon poly-ubiquitination of the target protein.


neuromuscular junction

description: The junction between the axon of a motor neuron and a muscle fiber. In response to the arrival of action potentials, the presynaptic button releases molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane of the muscle fiber, leading to a change in post-synaptic potential.


nuclear proteasome complex

description: A proteasome found in the nucleus of a cell.


cytosolic proteasome complex

description: A proteasome complex found in the cytosol of a cell.


nuclear proteasome regulatory particle

description: The regulatory subcomplex of a proteasome located in the nucleus of a cell.


name: cytosolic proteasome regulatory particle

description: A multisubunit complex located in the cytosol of a cell, which caps one or both ends of the proteasome core complex. This complex recognizes, unfolds ubiquitinated proteins and translocates them to the proteasome core complex.


nuclear proteasome core complex

description: The core complex of a proteasome located in the nucleus of a cell.


cytosolic proteasome core complex

description: The core complex of a proteasome located in the cytosol of a cell.


name: nuclear proteasome core complex, alpha-subunit complex

description: The subunits forming the outer ring of the core complex of a proteasome located in the nucleus of a cell.


name: cytosolic proteasome core complex, alpha-subunit complex

description: The proteasome core subcomplex that constitutes the two outer rings of the cytosolic proteasome core complex.


name: nuclear proteasome core complex, beta-subunit complex

description: The subunits forming the inner ring of the core complex of a proteasome located in the nucleus of a cell.


name: cytosolic proteasome core complex, beta-subunit complex

description: The proteasome core subcomplex that constitutes the two inner rings of the cytosolic proteasome core complex.


name: nuclear proteasome regulatory particle, base subcomplex

description: The subunits of the regulatory particle that directly associate with the core complex of a proteasome located in the nucleus of a cell.


name: cytosolic proteasome regulatory particle, base subcomplex

description: The subcomplex of the proteasome regulatory particle that directly associates with the proteasome core complex located in the cytosol of the cell.


name: nuclear proteasome regulatory particle, lid subcomplex

description: The subunits that form the peripheral lid of the regulatory particle of a proteasome located in the nucleus of a cell.


name: cytosolic proteasome regulatory particle, lid subcomplex

description: The subcomplex of the cytosolic proteasome regulatory particle that forms the peripheral lid, which is added on top of the base subcomplex.


spindle pole centrosome

description: A centrosome from which one pole of a mitotic or meiotic spindle is organized.


name: homologous chromosome orientation in meiotic metaphase I

description: The cell cycle process in which the sister centromeres and kinetochores of one chromosome are fused and orientated so the chromosomes attach to microtubules that emanate from the same spindle pole. This process ensures that homologous l chromosomes are segregated at anaphase of meiosis I.


regulation of fever generation

description: Any process that modulates the rate or extent of fever generation.


negative regulation of fever generation

description: Any process that stops, prevents, or reduces the rate or extent of fever generation.


positive regulation of fever generation

description: Any process that activates or increases the frequency, rate, or extent of fever generation.


receptor internalization

description: A receptor-mediated endocytosis process that results in the movement of receptors from the plasma membrane to the inside of the cell. The process begins when cell surface receptors are monoubiquitinated following ligand-induced activation. Receptors are subsequently taken up into endocytic vesicles from where they are either targeted to the lysosome or vacuole for degradation or recycled back to the plasma membrane.


ubiquitin conjugating enzyme binding

description: Binding to a ubiquitin conjugating enzyme, any of the E2 proteins.


ubiquitin protein ligase binding

description: Binding to a ubiquitin protein ligase enzyme, any of the E3 proteins.


beta-endorphin binding

description: Binding to beta-endorphin, a peptide generated by the cleavage of pro-opiomelanocortin.


telomeric loop formation

description: The process in which linear telomeric DNA is remodeled into duplex loops, by the invasion of a 3' single-stranded overhang into the duplex region.


opioid receptor binding

description: Binding to an opioid receptor.


name: synaptic vesicle fusion to presynaptic active zone membrane

description: Fusion of the membrane of a synaptic vesicle with the presynaptic active zone membrane, thereby releasing its cargo neurotransmitters into the synaptic cleft.


name: regulation of synaptic vesicle fusion to presynaptic active zone membrane

description: Any process that modulates the frequency, rate or extent of synaptic vesicle fusion to the presynaptic membrane.


name: negative regulation of synaptic vesicle fusion to presynaptic active zone membrane

description: Any process that stops, prevents, or reduces the frequency, rate or extent of synaptic vesicle fusion to the presynaptic membrane.


name: positive regulation of synaptic vesicle fusion to presynaptic active zone membrane

description: Any process that activates or increases the frequency, rate or extent of synaptic vesicle fusion to the presynaptic membrane.


xanthophore

description: A chromatophore containing yellow pigment.


replication fork barrier binding

description: Binding to replication fork barriers, sites that inhibit the progress of replication forks.


name: adenylate cyclase-inhibiting opioid receptor signaling pathway

description: An adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway initiated by an opioid binding to its receptor, and ending with the regulation of a downstream cellular process.


name: regulation of neuronal synaptic plasticity in response to neurotrophin

description: The process in which a neurotrophic factor induces neuronal synaptic plasticity, the ability of neuronal synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers.


zymogen activation

description: The proteolytic processing of an inactive enzyme to an active form.


plasminogen activation

description: The process in which inactive plasminogen is processed to active plasmin. This process includes cleavage at an internal Arg-Val site to form an N-terminal A-chain and C-terminal B-chain held together by a disulfide bond, and can include further proteolytic cleavage events to remove the preactivation peptide.


killing of cells of another organism

description: Any process in an organism that results in the killing of cells of another organism, including in some cases the death of the other organism. Killing here refers to the induction of death in one cell by another cell, not cell-autonomous death due to internal or other environmental conditions.


regulation of myelination

description: Any process that modulates the frequency, rate or extent of the formation of a myelin sheath around nerve axons.


negative regulation of myelination

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the formation of a myelin sheath around nerve axons.


positive regulation of myelination

description: Any process that activates or increases the frequency, rate or extent of the formation of a myelin sheath around nerve axons.


regulation of nervous system process

description: Any process that modulates the frequency, rate or extent of a neurophysiological process, an organ system process carried out by any of the organs or tissues of the nervous system.


name: negative regulation of nervous system process

description: Any process that stops, prevents, or reduces the frequency, rate or extent of a neurophysiological process.


name: positive regulation of nervous system process

description: Any process that activates or increases the frequency, rate or extent of a neurophysiological process.


regulation of protein stability

description: Any process that affects the structure and integrity of a protein, altering the likelihood of its degradation or aggregation.


protein destabilization

description: Any process that decreases the stability of a protein, making it more vulnerable to degradative processes or aggregation.


heat generation

description: Any homeostatic process in which an organism produces heat, thereby raising its internal temperature.


regulation of heat generation

description: Any process that modulates the rate or extent of heat generation.


negative regulation of heat generation

description: Any process that stops, prevents, or reduces the rate or extent of heat generation.


positive regulation of heat generation

description: Any process that activates or increases the rate or extent of heat generation.


heat dissipation

description: Any homeostatic process in which an organism releases excess heat to the environment, thereby lowering its internal temperature.


regulation of heat dissipation

description: Any process that modulates the rate or extent of heat dissipation.


negative regulation of heat dissipation

description: Any process that stops, prevents, or reduces the rate or extent of heat dissipation.


positive regulation of heat dissipation

description: Any process that activates or increases the rate or extent of heat dissipation.


description: The series of molecular signals initiated by the binding of a lipopolysaccharide (LPS) to a receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. Lipopolysaccharides are major components of the outer membrane of Gram-negative bacteria, making them prime targets for recognition by the immune system.


name: regulation of lipopolysaccharide-mediated signaling pathway

description: Any process that modulates the frequency, rate or extent of signaling in response to detection of lipopolysaccharide.


name: negative regulation of lipopolysaccharide-mediated signaling pathway

description: Any process that stops, prevents, or reduces the frequency, rate or extent of signaling in response to detection of lipopolysaccharide.


name: positive regulation of lipopolysaccharide-mediated signaling pathway

description: Any process that activates or increases the frequency, rate or extent of signaling in response to detection of lipopolysaccharide.


response to nutrient levels

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of nutrients.


cellular response to nutrient levels

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of nutrients.


cellular response to nutrient

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nutrient stimulus.


primary cell septum biogenesis

description: A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a primary cell septum following nuclear division.


A band

description: The dark-staining region of a sarcomere, in which myosin thick filaments are present; the center is traversed by the paler H zone, which in turn contains the M line.


H zone

description: A relatively pale zone traversing the center of the A band of a sarcomere, visible in relaxed muscle fibers; consists of the central portion of thick (myosin) filaments that are not overlapped by thin (actin) filaments.


I band

description: A region of a sarcomere that appears as a light band on each side of the Z disc, comprising a region of the sarcomere where thin (actin) filaments are not overlapped by thick (myosin) filaments; contains actin, troponin, and tropomyosin; each sarcomere includes half of an I band at each end.


name: plasma membrane-derived thylakoid membrane

description: The pigmented membrane of a plasma membrane-derived thylakoid.


G-protein beta/gamma-subunit complex

description: The heterodimer formed by the beta and gamma subunits of a heterotrimeric G protein, which dissociates from the alpha subunit upon guanine nuclotide exchange.


G-protein beta-subunit binding

description: Binding to a G-protein beta subunit.


G-protein gamma-subunit binding

description: Binding to a G-protein gamma subunit.


name: G-protein beta/gamma-subunit complex binding

description: Binding to a complex of G-protein beta/gamma subunits.


adenosine receptor binding

description: Binding to an adenosine receptor.


A1 adenosine receptor binding

description: Binding to an A1 adenosine receptor.


A2A adenosine receptor binding

description: Binding to an A2A adenosine receptor.


A2B adenosine receptor binding

description: Binding to an A2B adenosine receptor.


A3 adenosine receptor binding

description: Binding to an A3 adenosine receptor.


adrenergic receptor binding

description: Binding to an adrenergic receptor.


alpha-1A adrenergic receptor binding

description: Binding to an alpha-1A adrenergic receptor.


alpha-1B adrenergic receptor binding

description: Binding to an alpha-1B adrenergic receptor.


alpha-1D adrenergic receptor binding

description: Binding to an alpha-1D adrenergic receptor.


alpha-2A adrenergic receptor binding

description: Binding to an alpha-2A adrenergic receptor.


alpha-2B adrenergic receptor binding

description: Binding to an alpha-2B adrenergic receptor.


alpha-2C adrenergic receptor binding

description: Binding to an alpha-2C adrenergic receptor.


beta-1 adrenergic receptor binding

description: Binding to a beta-1 adrenergic receptor.


beta-2 adrenergic receptor binding

description: Binding to a beta-2 adrenergic receptor.


beta-3 adrenergic receptor binding

description: Binding to a beta-3 adrenergic receptor.


adrenomedullin receptor binding

description: Binding to an adrenomedullin receptor.


angiotensin receptor binding

description: Binding to an angiotensin receptor.


type 1 angiotensin receptor binding

description: Binding to a type 1 angiotensin receptor.


type 2 angiotensin receptor binding

description: Binding to a type 2 angiotensin receptor.


apelin receptor binding

description: Binding to an apelin receptor.


bombesin receptor binding

description: Binding to a bombesin receptor.


subtype 3 bombesin receptor binding

description: Binding to a subtype 3 bombesin receptor.


endothelin A receptor binding

description: Binding to an endothelin A receptor.


endothelin B receptor binding

description: Binding to an endothelin B receptor.


name: gastrin-releasing peptide receptor binding

description: Binding to a gastrin-releasing peptide receptor.


neuromedin B receptor binding

description: Binding to a neuromedin B receptor.


bradykinin receptor binding

description: Binding to a bradykinin receptor.


B1 bradykinin receptor binding

description: Binding to a B1 bradykinin receptor.


B2 bradykinin receptor binding

description: Binding to a B2 bradykinin receptor.


name: C5a anaphylatoxin chemotactic receptor binding

description: Binding to a C5a anaphylatoxin chemotactic receptor.


name: C5L2 anaphylatoxin chemotactic receptor binding

description: Binding to a C5L2 anaphylatoxin chemotactic receptor.


calcitonin receptor binding

description: Binding to a calcitonin receptor.


cannabinoid receptor binding

description: Binding to a cannabinoid receptor.


type 1 cannabinoid receptor binding

description: Binding to a type 1 cannabinoid receptor.


type 2 cannabinoid receptor binding

description: Binding to a type 2 cannabinoid receptor.


haptoglobin binding

description: Binding to a haptoglobin, any alpha2 globulin of blood plasma that can combine with free oxyhemoglobin to form a stable complex.


hemoglobin alpha binding

description: Binding to a hemoglobin alpha chain.


hemoglobin beta binding

description: Binding to a hemoglobin beta chain.


CXCR4 chemokine receptor binding

description: Binding to a CXCR4 chemokine receptor.


CXCR5 chemokine receptor binding

description: Binding to a CXCR5 chemokine receptor.


CXCR6 chemokine receptor binding

description: Binding to a CXCR6 chemokine receptor.


CCR1 chemokine receptor binding

description: Binding to a CCR1 chemokine receptor.


CCR2 chemokine receptor binding

description: Binding to a CCR2 chemokine receptor.


CCR3 chemokine receptor binding

description: Binding to a CCR3 chemokine receptor.


CCR4 chemokine receptor binding

description: Binding to a CCR4 chemokine receptor.


CCR5 chemokine receptor binding

description: Binding to a CCR5 chemokine receptor.


CCR6 chemokine receptor binding

description: Binding to a CCR6 chemokine receptor.


CCR7 chemokine receptor binding

description: Binding to a CCR7 chemokine receptor.


CCR8 chemokine receptor binding

description: Binding to a CCR8 chemokine receptor.


CCR9 chemokine receptor binding

description: Binding to a CCR9 chemokine receptor.


CCR10 chemokine receptor binding

description: Binding to a CCR10 chemokine receptor.


CCR11 chemokine receptor binding

description: Binding to a CCR11 chemokine receptor.


CX3C chemokine receptor binding

description: Binding to a CX3C chemokine receptor.


XCR1 chemokine receptor binding

description: Binding to a XCR1 chemokine receptor.


cholecystokinin receptor binding

description: Binding to a cholecystokinin receptor.


type A cholecystokinin receptor binding

description: Binding to a type A cholecystokinin receptor.


name: type B gastrin/cholecystokinin receptor binding

description: Binding to a type B gastrin/cholecystokinin receptor.


cysteinyl leukotriene receptor binding

description: Binding to a cysteinyl leukotriene receptor.


name: type 1 cysteinyl leukotriene receptor binding

description: Binding to a type 1 cysteinyl leukotriene receptor.


name: type 2 cysteinyl leukotriene receptor binding

description: Binding to a type 2 cysteinyl leukotriene receptor.


D1 dopamine receptor binding

description: Binding to a D1 dopamine receptor.


D2 dopamine receptor binding

description: Binding to a D2 dopamine receptor.


D3 dopamine receptor binding

description: Binding to a D3 dopamine receptor.


D4 dopamine receptor binding

description: Binding to a D4 dopamine receptor.


D5 dopamine receptor binding

description: Binding to a D5 dopamine receptor.


name: endothelial differentiation G protein-coupled receptor binding

description: Binding to an endothelial differentiation G protein-coupled receptor.


name: Edg-1 sphingosine 1-phosphate receptor binding

description: Binding to an Edg-1 sphingosine 1-phosphate receptor.


name: Edg-2 lysophosphatidic acid receptor binding

description: Binding to an Edg-2 lysophosphatidic acid receptor.


name: Edg-3 sphingosine 1-phosphate receptor binding

description: Binding to an Edg-3 sphingosine 1-phosphate receptor.


name: Edg-4 lysophosphatidic acid receptor binding

description: Binding to an Edg-4 lysophosphatidic acid receptor.


name: Edg-5 sphingosine 1-phosphate receptor binding

description: Binding to an Edg-5 sphingosine 1-phosphate receptor.


name: Edg-6 sphingosine 1-phosphate receptor binding

description: Binding to an Edg-6 sphingosine 1-phosphate receptor.


name: Edg-7 lysophosphatidic acid receptor binding

description: Binding to an Edg-7 lysophosphatidic acid receptor.


fMet-Leu-Phe receptor binding

description: Binding to a fMet-Leu-Phe receptor.


name: follicle-stimulating hormone receptor binding

description: Binding to a follicle-stimulating hormone receptor.


galanin receptor binding

description: Binding to a galanin receptor.


type 1 galanin receptor binding

description: Binding to a type 1 galanin receptor.


type 2 galanin receptor binding

description: Binding to a type 2 galanin receptor.


type 3 galanin receptor binding

description: Binding to a type 3 galanin receptor.


name: gastric inhibitory polypeptide receptor binding

description: Binding to a gastric inhibitory polypeptide receptor.


ghrelin receptor binding

description: Binding to a ghrelin receptor.


glucagon receptor binding

description: Binding to a glucagon receptor.


name: growth hormone-releasing hormone receptor binding

description: Binding to a growth hormone-releasing hormone receptor.


type 1 orexin receptor binding

description: Binding to a type 1 orexin receptor.


type 2 orexin receptor binding

description: Binding to a type 2 orexin receptor.


kisspeptin receptor binding

description: Binding to a kisspeptin receptor.


leukotriene receptor binding

description: Binding to a leukotriene receptor.


name: lutropin-choriogonadotropic hormone receptor binding

description: Binding to a lutropin-choriogonadotropic hormone receptor.


name: melanin-concentrating hormone receptor binding

description: Binding to a melanin-concentrating hormone receptor.


name: type 1 melanin-concentrating hormone receptor binding

description: Binding to a type 1 melanin-concentrating hormone receptor.


name: type 2 melanin-concentrating hormone receptor binding

description: Binding to a type 2 melanin-concentrating hormone receptor.


melanocortin receptor binding

description: Binding to a melanocortin receptor.


corticotropin hormone receptor binding

description: Binding to a corticotropin hormone receptor.


type 3 melanocortin receptor binding

description: Binding to a type 3 melanocortin receptor.


type 4 melanocortin receptor binding

description: Binding to a type 4 melanocortin receptor.


type 5 melanocortin receptor binding

description: Binding to a type 5 melanocortin receptor.


melatonin receptor binding

description: Binding to a melatonin receptor.


type 1A melatonin receptor binding

description: Binding to a type 1A melatonin receptor.


type 1B melatonin receptor binding

description: Binding to a type 1B melatonin receptor.


H9 melatonin receptor binding

description: Binding to a H9 melatonin receptor.


motilin receptor binding

description: Binding to a motilin receptor.


name: G protein-coupled acetylcholine receptor binding

description: Binding to a G protein-coupled acetylcholine receptor.


G protein-coupled GABA receptor binding

description: Binding to a G protein-coupled (metabotropic) GABA receptor.


name: type 1 metabotropic GABA receptor binding

description: Binding to a type 1 metabotropic GABA receptor.


name: type 2 metabotropic GABA receptor binding

description: Binding to a type 2 metabotropic GABA receptor.


name: type 1 metabotropic glutamate receptor binding

description: Binding to a type 1 metabotropic glutamate receptor.


name: type 2 metabotropic glutamate receptor binding

description: Binding to a type 2 metabotropic glutamate receptor.


name: type 3 metabotropic glutamate receptor binding

description: Binding to a type 3 metabotropic glutamate receptor.


name: type 4 metabotropic glutamate receptor binding

description: Binding to a type 4 metabotropic glutamate receptor.


name: type 5 metabotropic glutamate receptor binding

description: Binding to a type 5 metabotropic glutamate receptor.


name: type 6 metabotropic glutamate receptor binding

description: Binding to a type 6 metabotropic glutamate receptor.


name: type 7 metabotropic glutamate receptor binding

description: Binding to a type 7 metabotropic glutamate receptor.


name: type 8 metabotropic glutamate receptor binding

description: Binding to a type 8 metabotropic glutamate receptor.


name: G protein-coupled histamine receptor binding

description: Binding to a G protein-coupled (metabotropic) histamine receptor.


H1 histamine receptor binding

description: Binding to a H1 histamine receptor.


H2 histamine receptor binding

description: Binding to a H2 histamine receptor.


H3 histamine receptor binding

description: Binding to a H3 histamine receptor.


H4 histamine receptor binding

description: Binding to a H4 histamine receptor.


name: G protein-coupled nucleotide receptor binding

description: Binding to a G protein-coupled (metabotropic) nucleotide receptor.


P2Y1 nucleotide receptor binding

description: Binding to a P2Y1 nucleotide receptor.


P2Y2 nucleotide receptor binding

description: Binding to a P2Y2 nucleotide receptor.


P2Y4 nucleotide receptor binding

description: Binding to a P2Y4 nucleotide receptor.


P2Y5 nucleotide receptor binding

description: Binding to a P2Y5 nucleotide receptor.


P2Y6 nucleotide receptor binding

description: Binding to a P2Y6 nucleotide receptor.


P2Y8 nucleotide receptor binding

description: Binding to a P2Y8 nucleotide receptor.


P2Y9 nucleotide receptor binding

description: Binding to a P2Y9 nucleotide receptor.


P2Y10 nucleotide receptor binding

description: Binding to a P2Y10 nucleotide receptor.


P2Y11 nucleotide receptor binding

description: Binding to a P2Y11 nucleotide receptor.


name: G protein-coupled serotonin receptor binding

description: Binding to a metabotropic serotonin receptor.


type 1B serotonin receptor binding

description: Binding to a type 1B serotonin receptor.


type 1D serotonin receptor binding

description: Binding to a type 1D serotonin receptor.


type 1E serotonin receptor binding

description: Binding to a type 1E serotonin receptor.


type 1F serotonin receptor binding

description: Binding to a type 1F serotonin receptor.


type 2A serotonin receptor binding

description: Binding to a type 2A serotonin receptor.


type 2B serotonin receptor binding

description: Binding to a type 2B serotonin receptor.


type 2C serotonin receptor binding

description: Binding to a type 2C serotonin receptor.


type 4 serotonin receptor binding

description: Binding to a type 4 serotonin receptor.


type 5A serotonin receptor binding

description: Binding to a type 5A serotonin receptor.


type 5B serotonin receptor binding

description: Binding to a type 5B serotonin receptor.


type 6 serotonin receptor binding

description: Binding to a type 6 serotonin receptor.


type 7 serotonin receptor binding

description: Binding to a type 7 serotonin receptor.


neurokinin receptor binding

description: Binding to a neurokinin receptor.


substance P receptor binding

description: Binding to a substance P receptor.


neuromedin K receptor binding

description: Binding to a neuromedin K receptor.


substance K receptor binding

description: Binding to a substance K receptor.


haptoglobin-hemoglobin complex

description: A protein complex formed by the stable binding of a haptoglobin to hemoglobin.


type 1 neuromedin U receptor binding

description: Binding to a type 1 neuromedin U receptor.


type 2 neuromedin U receptor binding

description: Binding to a type 2 neuromedin U receptor.


neuropeptide Y receptor binding

description: Binding to a neuropeptide Y receptor.


type 1 neuropeptide Y receptor binding

description: Binding to a type 1 neuropeptide Y receptor.


type 2 neuropeptide Y receptor binding

description: Binding to a type 2 neuropeptide Y receptor.


type 4 neuropeptide Y receptor binding

description: Binding to a type 4 neuropeptide Y receptor.


type 5 neuropeptide Y receptor binding

description: Binding to a type 5 neuropeptide Y receptor.


neurotensin receptor binding

description: Binding to a neurotensin receptor.


type 1 neurotensin receptor binding

description: Binding to a type 1 neurotensin receptor.


name: protection from non-homologous end joining at telomere

description: A process that prevents non-homologous end joining at telomere, thereby ensuring that telomeres do not fuse.


olfactory receptor binding

description: Binding to an olfactory receptor.


delta-type opioid receptor binding

description: Binding to a delta-type opioid receptor.


kappa-type opioid receptor binding

description: Binding to a kappa-type opioid receptor.


mu-type opioid receptor binding

description: Binding to a mu-type opioid receptor.


nociceptin receptor binding

description: Binding to a nociceptin receptor.


name: orexigenic neuropeptide QRFP receptor binding

description: Binding to an orexigenic neuropeptide QRFP receptor.


oxytocin receptor binding

description: Binding to an oxytocin receptor.


parathyroid hormone receptor binding

description: Binding to a parathyroid hormone receptor.


name: type 1 parathyroid hormone receptor binding

description: Binding to a type 1 parathyroid hormone receptor.


name: pituitary adenylate cyclase-activating polypeptide receptor binding

description: Binding to a pituitary adenylate cyclase-activating polypeptide receptor.


name: platelet activating factor receptor binding

description: Binding to a platelet activating factor receptor.


telomeric 3' overhang formation

description: The formation of the single stranded telomeric 3' overhang, a conserved feature that ranges in length from 12 nt in budding yeast to approximately 500 nt in humans.


name: prolactin-releasing peptide receptor binding

description: Binding to a prolactin-releasing peptide receptor.


prostanoid receptor binding

description: Binding to a prostanoid receptor.


prostaglandin D2 receptor binding

description: Binding to a prostaglandin D2 receptor.


name: EP1 subtype prostaglandin E2 receptor binding

description: Binding to an EP1 subtype prostaglandin E2 receptor.


name: EP2 subtype prostaglandin E2 receptor binding

description: Binding to an EP2 subtype prostaglandin E2 receptor.


name: EP3 subtype prostaglandin E2 receptor binding

description: Binding to an EP3 subtype prostaglandin E2 receptor.


name: EP4 subtype prostaglandin E2 receptor binding

description: Binding to an EP4 subtype prostaglandin E2 receptor.


prostaglandin F2-alpha receptor binding

description: Binding to a prostaglandin F2-alpha receptor.


prostacyclin receptor binding

description: Binding to a prostacyclin receptor.


thromboxane A2 receptor binding

description: Binding to a thromboxane A2 receptor.


proteinase activated receptor binding

description: Binding to a proteinase activated receptor.


name: type 1 proteinase activated receptor binding

description: Binding to a type 1 proteinase activated receptor.


name: type 2 proteinase activated receptor binding

description: Binding to a type 2 proteinase activated receptor.


name: type 3 proteinase activated receptor binding

description: Binding to a type 3 proteinase activated receptor.


name: type 4 proteinase activated receptor binding

description: Binding to a type 4 proteinase activated receptor.


secretin receptor binding

description: Binding to a secretin receptor.


somatostatin receptor binding

description: Binding to a somatostatin receptor.


type 1 somatostatin receptor binding

description: Binding to a type 1 somatostatin receptor.


type 2 somatostatin receptor binding

description: Binding to a type 2 somatostatin receptor.


type 3 somatostatin receptor binding

description: Binding to a type 3 somatostatin receptor.


type 4 somatostatin receptor binding

description: Binding to a type 4 somatostatin receptor.


type 5 somatostatin receptor binding

description: Binding to a type 5 somatostatin receptor.


taste receptor binding

description: Binding to a taste receptor.


type 1 member 1 taste receptor binding

description: Binding to a type 1 member 1 taste receptor.


type 1 member 2 taste receptor binding

description: Binding to a type 1 member 2 taste receptor.


type 1 member 3 taste receptor binding

description: Binding to a type 1 member 3 taste receptor.


name: lipid droplet transport along microtubule

description: The directed movement of a lipid droplet along a microtubule, mediated by motor proteins.


urotensin receptor binding

description: Binding to a urotensin receptor.


name: vasoactive intestinal polypeptide receptor binding

description: Binding to a vasoactive intestinal polypeptide receptor.


name: type 1 vasoactive intestinal polypeptide receptor binding

description: Binding to a type 1 vasoactive intestinal polypeptide receptor.


name: type 2 vasoactive intestinal polypeptide receptor binding

description: Binding to a type 2 vasoactive intestinal polypeptide receptor.


vasopressin receptor binding

description: Binding to a vasopressin receptor.


V1A vasopressin receptor binding

description: Binding to a V1A vasopressin receptor.


V1B vasopressin receptor binding

description: Binding to a V1B vasopressin receptor.


V2 vasopressin receptor binding

description: Binding to a V2 vasopressin receptor.


Tic complex

description: The translocon of the inner envelope of chloroplasts, which facilitates the import of proteins across the chloroplast inner membrane.


chromoplast envelope

description: The double lipid bilayer enclosing the chromoplast and separating its contents from the rest of the cytoplasm; includes the intermembrane space.


chromoplast inner membrane

description: The inner, i.e. lumen-facing, lipid bilayer of the chromoplast envelope; also faces the chromoplast stroma.


chromoplast outer membrane

description: The outer, i.e. cytoplasm-facing, lipid bilayer of the chromoplast envelope.


early endosome membrane

description: The lipid bilayer surrounding an early endosome.


late endosome membrane

description: The lipid bilayer surrounding a late endosome.


microbody membrane

description: The lipid bilayer surrounding a microbody.


endosome lumen

description: The volume enclosed by the membrane of an endosome.


early endosome lumen

description: The volume enclosed by the membrane of an early endosome.


late endosome lumen

description: The volume enclosed by the membrane of a late endosome.


microbody lumen

description: The volume enclosed by the membranes of a microbody.


glyoxysomal lumen

description: The volume enclosed by the membranes of a glyoxysome.


cytostome

description: Stable, specialized structure for the ingestion of food by the cell into phagosomes.


cytoproct

description: Stable, specialized structure for extrusion of waste by the cell into the surrounding medium.


oral apparatus

description: Complex basket- or funnel-like structure used by the cell to collect food and channel it to the cytostome; includes specialized sub-structures made up of closely-spaced cilia and underlying basal bodies and fibrillar systems.


contractile vacuole pore

description: Stable structure that regulates the flow of liquid between the contractile vacuole and the surrounding medium.


name: negative regulation of synaptic plasticity

description: A process that decreases synaptic plasticity, the ability of synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers.


name: positive regulation of synaptic plasticity

description: A process that increases synaptic plasticity, the ability of synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers.


regulation of synaptic metaplasticity

description: A process that modulates synaptic metaplasticity. Metaplasticity is a higher-order form of plasticity and is manifest as a change in the ability to induce subsequent synaptic plasticity that is the ability of synapses to change as circumstances require.


name: negative regulation of synaptic metaplasticity

description: A process that decreases synaptic metaplasticity. Metaplasticity is a higher-order form of plasticity and is manifest as a change in the ability to induce subsequent synaptic plasticity that is the ability of synapses to change as circumstances require.


name: positive regulation of synaptic metaplasticity

description: A process that increases synaptic metaplasticity. Metaplasticity is a higher-order form of plasticity and is manifest as a change in the ability to induce subsequent synaptic plasticity that is the ability of synapses to change as circumstances require.


vitamin B6 transport

description: The directed movement of any of the vitamin B6 compounds -- pyridoxal, pyridoxamine and pyridoxine and the active form, pyridoxal phosphate -- into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


pyridoxal transport

description: The directed movement of pyridoxal into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Pyridoxal, 3-hydroxy-5-(hydroxymethyl)-2-methyl-4-pyridinecarboxaldehyde, is one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate.


pyridoxal phosphate transport

description: The directed movement of pyridoxal phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore; pyridoxal phosphate is pyridoxal phosphorylated at the hydroxymethyl group of C-5, and is the active form of vitamin B6.


pyridoxamine transport

description: The directed movement of pyridoxamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Pyridoxamine, 4-(aminomethyl)-5-(hydroxymethyl)-2-methylpyridin-3-ol, is one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate.


pyridoxine transport

description: The directed movement of pyridoxine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Pyridoxine, 2-methyl-3-hydroxy-4,5-bis(hydroxymethyl)pyridine, is one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate.


name: vitamin B6 transmembrane transporter activity

description: Enables the transfer of any of the vitamin B6 compounds, pyridoxal, pyridoxamine and pyridoxine and the active form, pyridoxal phosphate, from one side of a membrane to the other.


name: pyridoxal transmembrane transporter activity

description: Enables the transfer of pyridoxal from one side of a membrane to the other. Pyridoxal, 3-hydroxy-5-(hydroxymethyl)-2-methyl-4-pyridinecarboxaldehyde, is one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate.


name: pyridoxal phosphate transmembrane transporter activity

description: Enables the transfer of pyridoxal phosphate from one side of a membrane to the other. Pyridoxal phosphate is pyridoxal phosphorylated at the hydroxymethyl group of C-5, and is the active form of vitamin B6.


name: pyridoxamine transmembrane transporter activity

description: Enables the transfer of pyridoxamine from one side of a membrane to the other. Pyridoxamine, 4-(aminomethyl)-5-(hydroxymethyl)-2-methylpyridin-3-ol, is one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate.


name: pyridoxine transmembrane transporter activity

description: Enables the transfer of pyridoxine from one side of a membrane to the other. Pyridoxine, 2-methyl-3-hydroxy-4,5-bis(hydroxymethyl)pyridine, is one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate.


TOR signaling

description: The series of molecular signals mediated by TOR (Target of rapamycin) proteins, members of the phosphoinositide (PI) 3-kinase related kinase (PIKK) family that act as serine/threonine kinases in response to nutrient availability or growth factors.


mitochondria-nucleus signaling pathway

description: The series of molecular signals that forms a pathway of communication from the mitochondria to the nucleus and initiates cellular changes in response to changes in mitochondrial function.


TORC1 complex

description: A protein complex that contains at least TOR (target of rapamycin) and Raptor (regulatory-associated protein of TOR), or orthologs of, in complex with other signaling components. Mediates the phosphorylation and activation of S6K. In Saccharomyces, the complex contains Kog1p, Lst8p, Tco89p, and either Tor1p or Tor2p.


TORC2 complex

description: A protein complex that contains at least TOR (target of rapamycin) and Rictor (rapamycin-insensitive companion of TOR), or orthologs of, in complex with other signaling components. Mediates the phosphorylation and activation of PKB (also called AKT). In Saccharomyces, the complex contains Avo1p, Avo2p, Tsc11p, Lst8p, Bit61p, Slm1p, Slm2p, and Tor2p.


mating-type region heterochromatin

description: Heterochromatic regions of the chromosome found at silenced mating-type loci.


filamentous actin

description: A two-stranded helical polymer of the protein actin.


i-AAA complex

description: Protease complex of the mitochondrial inner membrane whose catalytic residues lie on the intermembrane space side of the inner membrane; involved in mitochondrial protein turnover. Contains a subunit belonging to the AAA family of ATP-dependent metalloproteases.


name: regulation of glucocorticoid metabolic process

description: Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving glucocorticoids.


name: negative regulation of glucocorticoid metabolic process

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving glucocorticoids.


name: positive regulation of glucocorticoid metabolic process

description: Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving glucocorticoids.


name: regulation of glucocorticoid biosynthetic process

description: Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucocorticoids.


name: negative regulation of glucocorticoid biosynthetic process

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucocorticoids.


name: positive regulation of glucocorticoid biosynthetic process

description: Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucocorticoids.


name: regulation of glucocorticoid catabolic process

description: Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glucocorticoids.


name: negative regulation of glucocorticoid catabolic process

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glucocorticoids.


name: positive regulation of glucocorticoid catabolic process

description: Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glucocorticoids.


name: regulation of protein autophosphorylation

description: Any process that modulates the frequency, rate or extent of addition of the phosphorylation by a protein of one or more of its own residues.


name: negative regulation of protein autophosphorylation

description: Any process that stops, prevents or decreases the rate of the phosphorylation by a protein of one or more of its own residues.


name: positive regulation of protein autophosphorylation

description: Any process that activates or increases the frequency, rate or extent of the phosphorylation by a protein of one or more of its own residues.


name: short-chain fatty acid-CoA ligase activity

description: Catalysis of the reaction: a short-chain fatty acid + ATP + CoA = a short-chain fatty acyl-CoA + AMP + diphosphate. A short-chain fatty acid has an aliphatic tail containing fewer than 6 carbons.


name: medium-chain fatty acid-CoA ligase activity

description: Catalysis of the reaction: a medium-chain fatty acid + ATP + CoA = a medium-chain fatty acyl-CoA + AMP + diphosphate. A medium-chain fatty acid has an aliphatic tail containing 6 to 12 carbons.


name: very long-chain fatty acid-CoA ligase activity

description: Catalysis of the reaction: a very long-chain fatty acid + ATP + CoA = a very long-chain fatty acyl-CoA + AMP + diphosphate. A very long-chain fatty acid has an aliphatic tail containing more than 22 carbons.


name: corticosteroid receptor signaling pathway

description: A nuclear receptor-mediated signaling pathway initiated by a corticosteroid binding to an intracellular receptor of the nuclear receptor protein family, and ending with regulation of a downstream cellular process, e.g. transcription.


name: nuclear receptor-mediated mineralocorticoid signaling pathway

description: A nuclear receptor-mediated signaling pathway initiated by a mineralocorticoid binding to an intracellular receptor of the nuclear receptor protein family, and ending with regulation of a downstream cellular process, e.g. transcription.


response to corticosteroid

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticosteroid hormone stimulus. A corticosteroid is a steroid hormone that is produced in the adrenal cortex. Corticosteroids are involved in a wide range of physiologic systems such as stress response, immune response and regulation of inflammation, carbohydrate metabolism, protein catabolism, blood electrolyte levels, and behavior. They include glucocorticoids and mineralocorticoids.


nuclear cortisol receptor binding

description: Binding to a nuclear cortisol receptor.


name: nuclear mineralocorticoid receptor binding

description: Binding to a nuclear mineralocorticoid receptor.


nuclear cortisol receptor activity

description: Combining with cortisol and transmitting the signal within the cell to trigger a change in cell activity or function.


description: Catalysis of the reaction: N-beta-alanyl histamine + H2O = histamine + beta-alanine.


nuclear membrane

description: Either of the lipid bilayers that surround the nucleus and form the nuclear envelope; excludes the intermembrane space.


mitochondrial membrane

description: Either of the lipid bilayers that surround the mitochondrion and form the mitochondrial envelope.


organelle envelope

description: A double membrane structure enclosing an organelle, including two lipid bilayers and the region between them. In some cases, an organelle envelope may have more than two membranes.


organelle outer membrane

description: The outer, i.e. cytoplasm-facing in a cellular organelle, lipid bilayer of an organelle envelope.


chloroplast membrane

description: Either of the lipid bilayers that surround a chloroplast and form the chloroplast envelope.


organelle envelope lumen

description: The region between the inner and outer lipid bilayers of an organelle envelope.


chloroplast intermembrane space

description: The region between the inner and outer lipid bilayers of a chloroplast envelope.


chromoplast intermembrane space

description: The region between the inner and outer lipid bilayers of a chromoplast envelope.


membrane-enclosed lumen

description: The enclosed volume within a sealed membrane or between two sealed membranes. Encompasses the volume enclosed by the membranes of a particular organelle, e.g. endoplasmic reticulum lumen, or the space between the two lipid bilayers of a double membrane surrounding an organelle, e.g. nuclear envelope lumen.


plastid thylakoid

description: Any thylakoid within a plastid.


thylakoid lumen

description: The volume enclosed by a thylakoid membrane.


plastid thylakoid lumen

description: The volume enclosed by a plastid thylakoid membrane.


plasma membrane-derived thylakoid lumen

description: The volume enclosed by a plasma membrane-derived thylakoid.


nuclear lumen

description: The volume enclosed by the nuclear inner membrane.


vesicle

description: Any small, fluid-filled, spherical organelle enclosed by membrane.


vesicle lumen

description: The volume enclosed by the membrane or protein that forms a vesicle.


organelle subcompartment

description: A compartment that consists of a lumen and an enclosing membrane, and is part of an organelle.


Golgi cisterna

description: Any of the thin, flattened membrane-bounded compartments that form the central portion of the Golgi complex.


proteinoplast

description: A leucoplast in which protein is stored.


name: locomotion involved in locomotory behavior

description: Self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement.


bombesin receptor signaling pathway

description: A G protein-coupled receptor signaling pathway initiated by a bombesin binding to its receptor, and ending with the regulation of a downstream cellular process, e.g. transcription.


name: mRNA export from nucleus in response to heat stress

description: The directed movement of mRNA from the nucleus to the cytoplasm during a heat stimulus, a temperature stimulus above the optimal temperature for the organism; in particular, a process that enables an organism withstand exposure to temperatures that would otherwise lethally impair poly(A)+ mRNA-nucleus export.


name: regulation of actomyosin contractile ring contraction

description: Any process that modulates the frequency, rate or extent of contraction of the actomyosin ring involved in cytokinesis that takes place as part of a cell cycle.


energy transducer activity

description: The biological transducer activity that accepts energy and converts it to another form, often by transfer to another molecule within the cell.


light transducer activity

description: Absorbing energy from one or more photons and transferring their energy to another molecule, usually a protein, within the cell.


insulin-like growth factor I binding

description: Binding to insulin-like growth factor I.


insulin-like growth factor II binding

description: Binding to insulin-like growth factor II.


thioesterase binding

description: Binding to a thioesterase.


regulation of fatty acid beta-oxidation

description: Any process that modulates the frequency, rate or extent of fatty acid bbeta-oxidation.


name: negative regulation of fatty acid beta-oxidation

description: Any process that stops, prevents, or reduces the frequency, rate or extent of fatty acid beta-oxidation.


name: positive regulation of fatty acid beta-oxidation

description: Any process that activates or increases the frequency, rate or extent of fatty acid beta-oxidation.


description: Catalysis of the transfer an alpha-D-glucosyl residue in a (1->4)-alpha-D-glucan to the primary hydroxy group of glucose, free or combined in a (1->4)-alpha-D-glucan.


interleukin-28 receptor complex

description: A protein complex that binds interleukin-28 and interleukin-29. It is composed of an alpha and a beta receptor subunit (in human IFNLR1/IL28Ralpha & IL10RB) and either Interleukin-28 (IFNL2 or IFNL3) or Interleukin-29 (IFNL1).


interleukin-28 receptor binding

description: Binding to an interleukin-28 receptor.


name: signal transduction involved in positive regulation of conjugation with cellular fusion

description: The series of molecular signals that bring about the relay, amplification or dampening of a signal generated in response to a cue, such as starvation or pheromone exposure, in organisms that undergo conjugation with cellular fusion.


regulation of TOR signaling

description: Any process that modulates the frequency, rate or extent of TOR signaling.


negative regulation of TOR signaling

description: Any process that stops, prevents, or reduces the frequency, rate or extent of TOR signaling.


positive regulation of TOR signaling

description: Any process that activates or increases the frequency, rate or extent of TOR signaling.


early phagosome

description: A membrane-bounded intracellular vesicle as initially formed upon the ingestion of particulate material by phagocytosis.


phagolysosome

description: A membrane-bounded intracellular vesicle formed by maturation of an early phagosome following the ingestion of particulate material by phagocytosis; during maturation, phagosomes acquire markers of late endosomes and lysosomes.


ARF protein signal transduction

description: An intracellular signaling cassette in which a small monomeric GTPase of the ARF subfamily relays a signal.


name: regulation of ARF protein signal transduction

description: Any process that modulates the frequency, rate or extent of ARF protein signal transduction.


name: negative regulation of ARF protein signal transduction

description: Any process that stops, prevents, or reduces the frequency, rate or extent of ARF protein signal transduction.


name: positive regulation of ARF protein signal transduction

description: Any process that activates or increases the frequency, rate or extent of ARF protein signal transduction.


name: 2-methylbutanal reductase (NADPH) activity

description: Catalysis of the reaction: 2-methylbutanol + NADP+ = 2-methylbutanal + NADPH + H+.


mitochondrial cloud

description: A prominent mass in the cytoplasm of previtellogenic oocytes. The cloud contains both mitochondria and electron-dense granulofibrillar material (GFM) and is the source of germinal granule material.


ISG15-protein conjugation

description: The covalent addition to a protein of ISG15, a ubiquitin-like protein.


NELF complex

description: A complex of five proteins, designated NELF-A, -B, -C, -D, and -E in human, that can physically associate with RNP polymerase II to induce transcriptional pausing.


trypsinogen activation

description: The proteolytic processing of trypsinogen to the active form, trypsin.


name: positive regulation of insulin secretion

description: Any process that activates or increases the frequency, rate or extent of the regulated release of insulin.


response to cobalt ion

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cobalt ion (Co2+) stimulus.


response to magnesium ion

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a magnesium ion stimulus.


myosin light chain binding

description: Binding to a light chain of a myosin complex.


myosin head/neck binding

description: Binding to the head/neck region of a myosin heavy chain.


myosin tail binding

description: Binding to the tail region of a myosin heavy chain.


myosin I light chain binding

description: Binding to a light chain of a myosin I complex.


myosin I head/neck binding

description: Binding to the head/neck region of a myosin I heavy chain.


myosin I tail binding

description: Binding to the tail region of a myosin I heavy chain.


myosin II light chain binding

description: Binding to a light chain of a myosin II complex.


myosin II head/neck binding

description: Binding to the head/neck region of a myosin II heavy chain.


myosin II tail binding

description: Binding to the tail region of a myosin II heavy chain.


myosin heavy chain binding

description: Binding to a heavy chain of a myosin complex.


myosin I heavy chain binding

description: Binding to a heavy chain of a myosin I complex.


myosin II heavy chain binding

description: Binding to a heavy chain of a myosin II complex.


integrator complex

description: A protein complex that stably associates with the C-terminus of RNA polymerase II and mediates 3'-end processing of small nuclear RNAs generated by RNA polymerase II.


small-subunit processome

description: A large ribonucleoprotein complex that is an early preribosomal complex. In S. cerevisiae, it has a size of 80S and consists of the 35S pre-rRNA, early-associating ribosomal proteins most of which are part of the small ribosomal subunit, the U3 snoRNA and associated proteins.


name: NAD-dependent histone H3K14 deacetylase activity

description: Catalysis of the reaction: histone H3 N6-acetyl-L-lysine (position 14) + H2O = histone H3 L-lysine (position 14) + acetate. This reaction requires the presence of NAD, and represents the removal of an acetyl group from lysine at position 14 of the histone H3 protein.


mitochondrial DNA metabolic process

description: The chemical reactions and pathways involving mitochondrial DNA.


mitochondrial DNA catabolic process

description: The chemical reactions and pathways resulting in the breakdown of mitochondrial DNA.


DSIF complex

description: A heterodimeric protein complex formed of Spt4 and Spt5 proteins which is expressed in eukaryotes from yeast to man. DSIF is an inhibitory elongation factor that promotes RNA polymerase II transcriptional pausing, but can also stimulate transcriptional elongation under certain conditions, and may play a role in RNA processing via its physical association with mRNA capping enzymes.


name: guanyl-nucleotide exchange factor complex

description: A protein complex that stimulates the exchange of guanyl nucleotides associated with a GTPase.


description: A membrane-bounded flattened sac that is formed during micropexophagy between the membrane tips of an engulfing vacuole, completing the engulfment and sequestration of peroxisomes from the cytosol, and forming a micropexophagic body within the lumen of the vacuole.


mitosome

description: A double-membrane-bounded organelle that functions in iron-sulfur protein maturation; evolutionarily derived from mitochondria. The mitosome has been detected only in anaerobic or microaerophilic organisms that do not have mitochondria, such as Entamoeba histolytica, Giardia intestinalis and several species of Microsporidia. These organisms are not capable of gaining energy from oxidative phosphorylation, which is normally performed by mitochondria.


cardiolipin metabolic process

description: The chemical reactions and pathways involving cardiolipin, 1,3-bis(3-phosphatidyl)glycerol.


cardiolipin biosynthetic process

description: The chemical reactions and pathways resulting in the formation of cardiolipin, 1,3-bis(3-phosphatidyl)glycerol.


clathrin heavy chain binding

description: Binding to a clathrin heavy chain.


clathrin light chain binding

description: Binding to a clathrin light chain.


bile acid binding

description: Binding to a bile acid, a steroid carboxylic acids occurring in bile.


ciliary basal body organization

description: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a ciliary basal body, a short cylindrical array of microtubules and associated proteins found at the base of a eukaryotic cilium (also called flagellum).


name: negative regulation of translation in response to stress

description: Any process that stops, prevents or reduces the rate of translation as a result of a stimulus indicating the organism is under stress.


name: positive regulation of translation in response to stress

description: Any process that activates or increases the frequency, rate or extent of translation as a result of a stimulus indicating the organism is under stress.


name: negative regulation of translational initiation in response to stress

description: Any process that stops, prevents or reduces the rate of translation initiation as a result of a stimulus indicating the organism is under stress.


name: positive regulation of translational initiation in response to stress

description: Any process that activates or increases the frequency, rate or extent of translation initiation as a result of a stimulus indicating the organism is under stress.


bleb

description: A cell extension caused by localized decoupling of the cytoskeleton from the plasma membrane and characterized by rapid formation, rounded shape, and scarcity of organelles within the protrusion. Blebs are formed during apoptosis and other cellular processes, including cell locomotion, cell division, and as a result of physical or chemical stresses.


bleb assembly

description: The assembly of a bleb, a cell extension caused by localized decoupling of the cytoskeleton from the plasma membrane and characterized by rapid formation, rounded shape, and scarcity of organelles within the protrusion. Plasma membrane blebbing occurs during apoptosis and other cellular processes, including cell locomotion, cell division, and as a result of physical or chemical stresses.


name: negative regulation of translation in response to osmotic stress

description: Any process that stops, prevents or reduces the rate of translation as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.


name: positive regulation of translation in response to osmotic stress

description: Any process that activates or increases the frequency, rate or extent of translation as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.


name: negative regulation of translational initiation in response to osmotic stress

description: Any process that stops, prevents or reduces the rate of translation initiation, as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.


name: positive regulation of translational initiation in response to osmotic stress

description: Any process that activates or increases the frequency, rate or extent of translation initiation, as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.


name: maintenance of protein location in cell cortex

description: A process in which a protein or protein complex is maintained in a specific location in the cell cortex.


name: type IV site-specific deoxyribonuclease activity

description: Catalysis of the endonucleolytic cleavage of DNA in a site specific manner. Cleavage is dependent on the presence of a specific recognition site in the DNA which must be modified (e.g. methylated, hydroxymethylated, glucosyl-hydroxymethylated).


name: type IV site-specific deoxyribonuclease complex

description: A complex consisting of two proteins which acts as an endonuclease in DNA sequences containing a specific modified recognition site. Modifications may include methylation, hydroxymethylation, and glucosyl-hydroxymethylation.


regulation of nuclease activity

description: Any process that modulates the frequency, rate or extent of nuclease activity, the hydrolysis of ester linkages within nucleic acids.


name: regulation of deoxyribonuclease activity

description: Any process that modulates the frequency, rate or extent of deoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid.


name: regulation of endodeoxyribonuclease activity

description: Any process that modulates the frequency, rate or extent of endodeoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid by creating internal breaks.


name: regulation of restriction endodeoxyribonuclease activity

description: Any process that modulates the frequency, rate or extent of a restriction endodeoxyribonuclease activity, the catalysis of endonucleolytic cleavage of DNA in a site-specific manner, resulting in double-strand breaks.


name: negative regulation of restriction endodeoxyribonuclease activity

description: Any process that stops or reduces the rate of a restriction endodeoxyribonuclease activity, the catalysis of endonucleolytic cleavage of DNA in a site-specific manner, resulting in double-strand breaks.


name: negative regulation of nuclease activity

description: Any process that stops or reduces the rate of nuclease activity, the hydrolysis of ester linkages within nucleic acids.


name: positive regulation of nuclease activity

description: Any process that activates or increases the frequency, rate or extent of nuclease activity, the hydrolysis of ester linkages within nucleic acids.


name: negative regulation of deoxyribonuclease activity

description: Any process that stops or reduces the rate of deoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid.


name: positive regulation of deoxyribonuclease activity

description: Any process that activates or increases the frequency, rate or extent of deoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid.


name: negative regulation of endodeoxyribonuclease activity

description: Any process that stops or reduces the rate of endodeoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid by creating internal breaks.


name: positive regulation of endodeoxyribonuclease activity

description: Any process that activates or increases the frequency, rate or extent of endodeoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid by creating internal breaks.


name: negative regulation of type I site-specific deoxyribonuclease activity

description: Any process that stops or reduces the rate of type I restriction endodeoxyribonuclease activity.


name: negative regulation of type II site-specific deoxyribonuclease activity

description: Any process that stops or reduces the rate of type II restriction endodeoxyribonuclease activity.


name: negative regulation of type III site-specific deoxyribonuclease activity

description: Any process that stops or reduces the rate of type III restriction endodeoxyribonuclease activity.


name: negative regulation of type IV site-specific deoxyribonuclease activity

description: Any process that stops or reduces the rate of type IV restriction endodeoxyribonuclease activity.


name: regulation of type I site-specific deoxyribonuclease activity

description: Any process that modulates the frequency, rate or extent of a type I restriction endodeoxyribonuclease activity.


name: regulation of type II site-specific deoxyribonuclease activity

description: Any process that modulates the frequency, rate or extent of a type II restriction endodeoxyribonuclease activity.


name: regulation of type III site-specific deoxyribonuclease activity

description: Any process that modulates the frequency, rate or extent of a type III restriction endodeoxyribonuclease activity.


name: regulation of type IV site-specific deoxyribonuclease activity

description: Any process that modulates the frequency, rate or extent of a type IV restriction endodeoxyribonuclease activity.


name: negative regulation of NF-kappaB transcription factor activity

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of the transcription factor NF-kappaB.


NACHT domain binding

description: Binding to a NACHT (NAIP, CIITA, HET-E and TP1) domain. The NACHT domain consists of seven distinct conserved motifs, including an ATP/GTPase specific P-loop, a Mg2+-binding site and five more specific motifs.


Pyrin domain binding

description: Binding to a Pyrin (PAAD/DAPIN) domain, a protein-protein interaction domain that has the same fold as the Death domain.


negative regulation of protein binding

description: Any process that stops, prevents, or reduces the frequency, rate or extent of protein binding.


positive regulation of protein binding

description: Any process that activates or increases the frequency, rate or extent of protein binding.


SAM domain binding

description: Binding to a SAM (Sterile Alpha Motif) domain, which is a 70-amino acid protein sequence that participates in protein-protein, protein-lipid, and protein-RNA interactions and is conserved from lower to higher eukaryotes.


response to food

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a food stimulus; food is anything which, when taken into the body, serves to nourish or build up the tissues or to supply body heat.


regulation of response to food

description: Any process that modulates the frequency, rate or extent of a response to a food stimulus.


negative regulation of response to food

description: Any process that stops, prevents, or reduces the frequency, rate or extent of a response to a food stimulus.


positive regulation of response to food

description: Any process that activates, maintains, or increases the rate of a response to a food stimulus.


regulation of appetite

description: Any process which modulates appetite, the desire or physical craving for food.


negative regulation of appetite

description: Any process that reduces appetite.


positive regulation of appetite

description: Any process that increases appetite.


name: regulation of response to external stimulus

description: Any process that modulates the frequency, rate or extent of a response to an external stimulus.


name: negative regulation of response to external stimulus

description: Any process that stops, prevents, or reduces the frequency, rate or extent of a response to an external stimulus.


name: positive regulation of response to external stimulus

description: Any process that activates, maintains or increases the rate of a response to an external stimulus.


name: regulation of response to nutrient levels

description: Any process that modulates the frequency, rate or extent of a response to nutrient levels.


name: negative regulation of response to nutrient levels

description: Any process that stops, prevents, or reduces the frequency, rate or extent of a response to nutrient levels.


name: positive regulation of response to nutrient levels

description: Any process that activates or increases the frequency, rate or extent of a response to nutrient levels.


name: regulation of protein histidine kinase activity

description: Any process that modulates the frequency, rate or extent of protein histidine kinase activity.


name: negative regulation of protein histidine kinase activity

description: Any process that stops, prevents, or reduces the frequency, rate or extent of protein histidine kinase activity.


name: regulation of carbohydrate phosphatase activity

description: Any process that modulates the frequency, rate or extent of carbohydrate phosphatase activity, the catalysis of the hydrolysis of phosphate from a carbohydrate phosphate.


name: regulation of glucose-6-phosphatase activity

description: Any process that modulates the frequency, rate or extent of glucose-6-phosphatase activity, the catalysis of the reaction: D-glucose 6-phosphate + H2O = D-glucose + phosphate.


sorbose reductase activity

description: Catalysis of the reaction: D-glucitol + NADP+ = L-sorbose + H+ + NADPH. The reaction may occur, to a minor extent, in the reverse direction.


SMC loading complex

description: A protein complex required for the loading of a structural maintenance of chromosome (SMC) complex, such as cohesin, condensin or SMC5/SMC6, onto DNA. Appears to be eukaryotically conserved.


horsetail-astral microtubule array

description: An array of astral microtubules that emanates from the spindle pole body during meiosis and facilitates horsetail nuclear movement.