name: positive regulation of nematode larval development

description: Any process that increases the rate, frequency, or extent of nematode larval development, the process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew.


name: negative regulation of nematode larval development

category: biolink:BiologicalProcess biolink:Occurrent biolink:OntologyClass biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: Any process that decreases the rate, frequency, or extent of nematode larval development, the process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew.


regulation of dauer larval development

description: Any process that modulates the rate, frequency, or extent of dauer larval development, the process whose specific outcome is the progression of the dauer larva over time, through the facultative diapause of the dauer (enduring) larval stage, with specialized traits adapted for dispersal and long-term survival, with elevated stress resistance and without feeding.


name: positive regulation of dauer larval development

description: Any process that increases the rate, frequency, or extent of dauer larval development, the process whose specific outcome is the progression of the dauer larva over time, through the facultative diapause of the dauer (enduring) larval stage, with specialized traits adapted for dispersal and long-term survival, with elevated stress resistance and without feeding.


name: negative regulation of dauer larval development

description: Any process that decreases the rate, frequency, or extent of dauer larval development, the process whose specific outcome is the progression of the dauer larva over time, through the facultative diapause of the dauer (enduring) larval stage, with specialized traits adapted for dispersal and long-term survival, with elevated stress resistance and without feeding.


urethra development

description: The progression of the urethra over time from its initial formation to the mature structure. The urethra is a renal system organ that carries urine from the bladder to outside the body.


male urethra development

description: The progression of the male urethra over time from its initial formation to the mature structure. The male urethra is a renal system organ that carries urine from the bladder through the penis to outside the body.


female urethra development

description: The progression of the female urethra over time from its initial formation to the mature structure. The female urethra is a renal system organ that carries urine from the bladder to outside the body, exiting above the vaginal opening.


urethra epithelium development

description: The progression of the urethra epithelium over time from its initial formation to the mature structure. The urethra is a renal system organ that carries urine from the bladder to outside the body. The epithelium is the tubular, planar layer of cells through which the urine passes.


iris morphogenesis

description: The process in which the iris is generated and organized. The iris is an anatomical structure in the eye whose opening forms the pupil. The iris is responsible for controlling the diameter and size of the pupil and the amount of light reaching the retina.


ciliary body morphogenesis

description: The process in which the ciliary body generated and organized. The ciliary body is the circumferential tissue inside the eye composed of the ciliary muscle and ciliary processes.


regulation of neural retina development

description: Any process that modulates the rate, frequency, or extent of neural retina development, the progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells.


name: positive regulation of neural retina development

description: Any process that increases the rate, frequency, or extent of neural retina development, the progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells.


name: negative regulation of neural retina development

description: Any process that decreases the rate, frequency, or extent of neural retina development, the progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells.


chaperone-mediated protein folding

description: The process of inhibiting aggregation and assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure that is dependent on interaction with a chaperone.


name: positive regulation of prostaglandin secretion involved in immune response

description: Any process that activates or increases the frequency, rate or extent of the regulated release of a prostaglandin from a cell and contributes to the immune response.


left horn of sinus venosus development

description: The progression of the left horn of the sinus venosus from its initial formation to the mature structure.


right horn of sinus venosus development

description: The progression of the right horn of the sinus venosus from its formation to the mature structure.


name: positive regulation of myeloid leukocyte cytokine production involved in immune response

description: Any process that modulates the rate, frequency, or extent of the production of a cytokine that contributes to the immune response.


myeloid leukocyte cytokine production

description: Any process that contributes to cytokine production by a myeloid cell.


regulation of protein refolding

description: Any process that regulates the rate, frequency, or extent of protein refolding. Protein refolding is the process carried out by a cell that restores the biological activity of an unfolded or misfolded protein, using helper proteins such as chaperones.


name: negative regulation of protein refolding

description: Any process that decreases the rate, frequency, or extent of protein refolding. Protein refolding is the process carried out by a cell that restores the biological activity of an unfolded or misfolded protein, using helper proteins such as chaperones.


name: regulation of phospholipid translocation

description: Any process that modulates the frequency, rate or extent of the translocation, or flipping, of phospholipid molecules from one monolayer of a membrane bilayer to the opposite monolayer.


name: positive regulation of phospholipid translocation

description: Any process that increases the frequency, rate or extent of the translocation, or flipping, of phospholipid molecules from one monolayer of a membrane bilayer to the opposite monolayer.


name: negative regulation of phospholipid translocation

description: Any process that decreases the frequency, rate or extent of the translocation, or flipping, of phospholipid molecules from one monolayer of a membrane bilayer to the opposite monolayer.


name: regulation of turning behavior involved in mating

description: Any process that modulates the rate, frequency or extent of turning behavior involved in mating. Turning behavior is the sharp ventral turn performed by the male as he approaches either the hermaphrodite head or tail, whilst trying to locate his partner's vulva. Turning occurs via a sharp ventral coil of the male's tail.


name: positive regulation of turning behavior involved in mating

description: Any process that increases the rate, frequency or extent of turning behavior involved in mating. Turning behavior is the sharp ventral turn performed by the male as he approaches either the hermaphrodite head or tail, whilst trying to locate his partner's vulva. Turning occurs via a sharp ventral coil of the male's tail.


name: negative regulation of turning behavior involved in mating

description: Any process that decreases the rate, frequency or extent of turning behavior involved in mating. Turning behavior is the sharp ventral turn performed by the male as he approaches either the hermaphrodite head or tail, whilst trying to locate his partner's vulva. Turning occurs via a sharp ventral coil of the male's tail.


name: regulation of protein tyrosine kinase activity

description: Any process that modulates the rate, frequency, or extent of protein tyrosine kinase activity.


name: positive regulation of protein tyrosine kinase activity

description: Any process that increases the rate, frequency, or extent of protein tyrosine kinase activity.


name: negative regulation of protein tyrosine kinase activity

description: Any process that decreases the rate, frequency, or extent of protein tyrosine kinase activity.


name: lung neuroendocrine cell differentiation

description: The process in which a relatively unspecialized cell acquires specialized features of a neuroendocrine cell of the lung epithelium.


neuroendocrine cell differentiation

description: The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a neuroendocrine cell. A neuroendocrine cell is a cell that receives input form a neuron which controls the secretion of an endocrine substance.


name: stomach neuroendocrine cell differentiation

description: The process in which a relatively unspecialized cell acquires specialized features of a neuroendocrine cell of the stomach epithelium.


name: carotid body glomus cell differentiation

description: The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a glomus cell of the carotid body. The carotid body is a specialized chemosensory organ that helps respond to hypoxia.


adrenal chromaffin cell differentiation

description: The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of an adrenal chromaffin cell. An adrenal chromaffin cell is a neuroendocrine cell that stores epinephrine secretory vesicles.


name: regulation of stomach neuroendocrine cell differentiation

description: Any process that modulates the rate, frequency or extent of the differentiation of a neuroendocrine cell in the stomach.


name: negative regulation of stomach neuroendocrine cell differentiation

description: Any process that decreases the rate, frequency or extent of the differentiation of a neuroendocrine cell in the stomach.


seminal vesicle development

description: The progression of the seminal vesicle over time, from its formation to the mature structure. The seminal vesicle is a gland that contributes to the production of semen.


seminal vesicle epithelium development

description: The progression of the seminal vesicle epithelium over time, from its formation to the mature structure.


dense core granule organization

description: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a dense core granule. A dense core granule is a secretory organelle found in endocrine cells.


dense core granule biogenesis

description: A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a dense core granule. Includes biosynthesis of constituent macromolecules, and those macromolecular modifications that are involved in synthesis or assembly of the dense core granule.


name: epithelial-mesenchymal cell signaling involved in lung development

description: Any process that results in the transfer of information from an epithelial cell to a mesenchymal cell and contributes to the progression of the lung over time from its initial formation to the mature organ.


name: negative regulation of bud outgrowth involved in lung branching

description: Any process that decreases the rate, frequency, or extent of bud outgrowth involved in lung branching.


pancreas morphogenesis

description: Morphogenesis of the pancreas. Morphogenesis is the process in which anatomical structures are generated and organized.


name: branching involved in pancreas morphogenesis

description: The process in which the branches of the pancreas are generated and organized.


lung proximal/distal axis specification

description: The establishment, maintenance and elaboration of the proximal/distal axis of the lung. The proximal/distal axis of the lung is defined by a line that runs from the trachea to the alveoli.


ductus venosus closure

description: The morphogenesis process in which the ductus venosus changes to no longer permit blood flow after birth.


negative regulation of heart growth

description: Any process that decreases the rate or extent of heart growth. Heart growth is the increase in size or mass of the heart.


name: regulation of positive chemotaxis to cAMP

description: Any process that modulates the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP.


name: regulation of positive chemotaxis to cAMP by chlorinated alkylphenone

description: Any process that modulates the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of a chlorinated alkylphenone. An alkylphenone is an aromatic polyketide with methyl and chlorine substitutions.


name: regulation of positive chemotaxis to cAMP by DIF-1

description: Any process that modulates the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of DIF-1. DIF-1 is a chlorinated alkylphenone.


name: regulation of positive chemotaxis to cAMP by DIF-2

description: Any process that modulates the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of DIF-2. DIF-2 is a chlorinated alkylphenone.


name: positive regulation of positive chemotaxis to cAMP

description: Any process that increases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP.


name: negative regulation of positive chemotaxis to cAMP

description: Any process that decreases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP.


name: positive regulation of positive chemotaxis to cAMP by chlorinated alkylphenone

description: Any process that increases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of a chlorinated alkylphenone. An alkylphenone is an aromatic polyketide with methyl and chlorine substitutions.


name: negative regulation of positive chemotaxis to cAMP by chlorinated alkylphenone

description: Any process that decreases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of a chlorinated alkylphenone. An alkylphenone is an aromatic polyketide with methyl and chlorine substitutions.


name: positive regulation of positive chemotaxis to cAMP by DIF-1

description: Any process that increases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of DIF-1. DIF-1 is a chlorinated alkylphenone.


name: negative regulation of positive chemotaxis to cAMP by DIF-1

description: Any process that decreases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of DIF-1. DIF-1 is a chlorinated alkylphenone.


name: positive regulation of chemotaxis to cAMP by DIF-2

description: Any process that increases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of DIF-2. DIF-2 is a chlorinated alkylphenone.


name: negative regulation of positive chemotaxis to cAMP by DIF-2

description: Any process that decreases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of DIF-2. DIF-2 is a chlorinated alkylphenone.


pancreatic bud formation

description: The morphogenetic process in which the foregut region specified to become the pancreas forms a bud.


pancreas field specification

description: The process in which a specific region of the gut is delineated into the area in which the pancreas will develop.


pancreas induction

description: The close range interaction of two or more cells or tissues that causes the cells of the gut to change their fates and specify the development of the pancreas.


endopeptidase activator activity

category: biolink:MolecularActivity biolink:Occurrent biolink:OntologyClass biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: Binds to and increases the activity of an endopeptidase.


peptidase regulator activity

description: Binds to and modulates the activity of a peptidase, any enzyme that catalyzes the hydrolysis peptide bonds.


endopeptidase regulator activity

description: Binds to and modulates the activity of a peptidase, any enzyme that hydrolyzes nonterminal peptide bonds in polypeptides.


name: regulation of proteasomal protein catabolic process

description: Any process that modulates the rate, frequency, or extent of the chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds that is mediated by the proteasome.


bud dilation

description: The process in which a branch bud increases radially. A branch bud is the initial area of outgrowth in the formation of a new branch.


morphogenesis of a branching epithelium

description: The process in which the anatomical structures of a branched epithelium are generated and organized.


bud field specification

description: The regionalization process in which the identity of a bud primordium is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized.


lung secretory cell differentiation

description: The process in which a relatively unspecialized cell acquires specialized features of a lung secretory cell. A lung secretory cell is a specialized epithelial cell of the lung that contains large secretory granules in its apical part.


lung ciliated cell differentiation

description: The process in which a relatively unspecialized cell acquires specialized features of a lung ciliated cell. A lung ciliated cell is a specialized lung epithelial cell that contains cilia for moving substances released from lung secretory cells.


name: mesothelial-mesenchymal cell signaling involved in early lung development

description: Any process that mediates the transfer of information from a mesothelial cell to an epithelial cell and contributes to the development of the lung.


alveolar primary septum development

description: The progression of a primary alveolar septum over time, from its formation to the mature structure. A primary alveolar septum is a specialized epithelium that surrounds the saccule as it forms.


alveolar secondary septum development

description: The progression of a secondary alveolar septum over time, from its formation to the mature structure. A secondary alveolar septum is a specialized epithelium that subdivides the initial saccule.


lung smooth muscle development

description: The process whose specific outcome is the progression of smooth muscle in the lung over time, from its formation to the mature structure.


Peyer's patch morphogenesis

description: The process in which a Peyer's patch is generated and organized. Peyer's patches are typically found as nodules associated with gut epithelium with distinct internal structures including B- and T-zones for the activation of lymphocytes.


endocardial endothelium development

description: The progression of the endocardial endothelium over time, from its initial formation to the mature structure. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers.


name: extracellular matrix organization involved in endocardium development

description: A process which results in the assembly, arrangement of constituent parts, or disassembly of an extracellular matrix of the endocardium. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers.


renal system segmentation

description: The regionalization process that divides an the renal system into a series of segments along its proximal/distal axis.


trachea submucosa development

description: The progression of the trachea submucosa over time from its formation to the mature structure. The trachea submucosa is made up of the glands and elastic tissue that lie under the mucosa in the trachea.


trachea gland development

description: The progression of a trachea gland over time, from its formation to the mature structure. Trachea glands are found under the mucus of the trachea and secrete mucus, and agents that help protect the lung from injury and infection.


endothelial tube morphogenesis

description: The process in which the anatomical structures of a tube are generated and organized from an endothelium. Endothelium refers to the layer of cells lining blood vessels, lymphatics, the heart, and serous cavities, and is derived from bone marrow or mesoderm. Corneal endothelium is a special case, derived from neural crest cells.


name: pulmonary artery endothelial tube morphogenesis

description: The process in which the anatomical structures of a tube are generated and organized from the pulmonary artery endothelium. An pulmonary artery endothelium is an epithelium that lines the pulmonary artery.


pulmonary artery morphogenesis

description: The process in which the anatomical structures of the pulmonary artery are generated and organized. The pulmonary artery is the artery that carries blood from the heart to the lungs.


mRNA destabilization

description: Any process that decreases the stability of an mRNA molecule, making it more vulnerable to degradative processes. Messenger RNA is the intermediate molecule between DNA and protein. It includes UTR and coding sequences. It does not contain introns.


3'-UTR-mediated mRNA destabilization

description: An mRNA destabilization process in which one or more RNA-binding proteins associate with the 3'-untranslated region (UTR) of an mRNA.


name: establishment of bipolar cell polarity involved in cell morphogenesis

description: The specification and formation of bipolar intracellular organization or cell growth patterns that contribute to cell morphogenesis. Bipolar organization is the organization that is a mirror image along an axis from a plane.


name: regulation of establishment of bipolar cell polarity regulating cell shape

description: Any process that modulates the rate, frequency or extent of the establishment of bipolar cell polarity that contributes to the shape of a cell.


name: positive regulation of establishment of bipolar cell polarity regulating cell shape

description: Any process that increases the rate, frequency or extent of the establishment of bipolar cell polarity that regulates the shape of a cell.


name: establishment of monopolar cell polarity

description: The specification and formation of monopolar intracellular organization or cell growth patterns. Monopolar cell organization is directional organization along an axis.


endoplasmic reticulum polarization

description: The endoplasmic reticulum organization process that results in the structure of the endoplasmic reticulum being oriented in the cell. Endoplasmic reticulum polarization serves as a mechanism to compartmentalize cellular activities and to establish cell polarity.


name: regulation of hair follicle placode formation

description: Any process that modulates the rate, frequency, or extent of hair follicle placode formation, the developmental process in which a hair placode forms. An hair follicle placode is a thickening of the ectoderm that will give rise to the hair follicle bud.


name: positive regulation of hair placode formation

description: Any process that increases the rate, frequency, or extent of hair follicle placode formation, the developmental process in which a hair placode forms. An hair follicle placode is a thickening of the ectoderm that will give rise to the hair follicle bud.


name: negative regulation of hair follicle placode formation

description: Any process that decreases the rate, frequency, or extent of hair follicle placode formation, the developmental process in which a hair placode forms. An hair follicle placode is a thickening of the ectoderm that will give rise to the hair follicle bud.


establishment of bipolar cell polarity

description: The specification and formation of bipolar intracellular organization or cell growth patterns. Bipolar organization is the organization that is a mirror image along an axis from a plane.


name: regulation of establishment of bipolar cell polarity

description: Any process that modulates the rate, frequency or extent of the establishment of bipolar cell polarity. Bipolar organization is the organization that is a mirror image along an axis from a plane.


name: positive regulation of establishment of bipolar cell polarity

description: Any process that increases the rate, frequency or extent of the establishment of bipolar cell polarity.


type I terminal bouton

category: biolink:CellularComponent biolink:AnatomicalEntity biolink:PhysicalEssence biolink:OrganismalEntity biolink:SubjectOfInvestigation biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: Terminal inflated portion of the axon of a glutamatergic neuron, containing the specialized apparatus necessary to release neurotransmitters that will induce the contraction of muscle. The axon terminus is considered to be the whole region of thickening and the terminal bouton is a specialized region of it.


type II terminal bouton

description: Terminal inflated portion of the axon of a non-glutamatergic neuron, containing the specialized apparatus necessary to release neurotransmitters at a regulatory synapse. The axon terminus is considered to be the whole region of thickening and the terminal bouton is a specialized region of it.


type Ib terminal bouton

description: Terminal inflated portion of the axon of a glutamatergic neuron, containing the specialized apparatus necessary for the tonic release neurotransmitters that will induce the contraction of muscle. Type Ib terminal boutons are larger than type Is terminal boutons.


type Is terminal bouton

description: Terminal inflated portion of the axon of a glutamatergic neuron, containing the specialized apparatus necessary for the phasic release neurotransmitters that will induce the contraction of muscle. Type Is terminal boutons are smaller than type Ib terminal boutons.


name: regulation of insulin secretion involved in cellular response to glucose stimulus

description: Any process that modulates the frequency, rate or extent of the regulated release of insulin that contributes to the response of a cell to glucose.


name: negative regulation of insulin secretion involved in cellular response to glucose stimulus

description: Any process that decreases the frequency, rate or extent of the regulated release of insulin that contributes to the response of a cell to glucose.


mammary gland epithelium development

description: The process whose specific outcome is the progression of the mammary gland epithelium over time, from its formation to the mature structure. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk.


regulation of chondrocyte development

description: Any process that modulates the rate, frequency, or extent of the process whose specific outcome is the progression of a chondrocyte over time, from its commitment to its mature state. Chondrocyte development does not include the steps involved in committing a chondroblast to a chondrocyte fate.


name: negative regulation of chondrocyte development

description: Any process that decreases the rate, frequency, or extent of the process whose specific outcome is the progression of a chondrocyte over time, from its commitment to its mature state. Chondrocyte development does not include the steps involved in committing a chondroblast to a chondrocyte fate.


regulation of dermatome development

description: Any process that modulates the rate, frequency, or extent of the progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin.


name: positive regulation of dermatome development

description: Any process that increases the rate, frequency, or extent of the progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin.


name: negative regulation of dermatome development

description: Any process that decreases the rate, frequency, or extent of the progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin.


name: negative regulation of silent mating-type cassette heterochromatin formation

description: Any process that decreases the frequency, rate, or extent of heterochromatin formation at silent mating-type cassette.


name: regulation of rDNA heterochromatin formation

description: Any process that modulates the rate, frequency, or extent of rDNA heterochromatin formation.


name: negative regulation of rDNA heterochromatin formation

description: Any process that decreases the rate, frequency, or extent of ribosomal DNA heterochromatin formation.


name: positive regulation of sclerotome development

description: Any process that increases the rate, frequency, or extent of the progression of the sclerotome over time, from its initial formation to the mature structure. The sclerotome is the portion of the somite that will give rise to a vertebra.


regulation of sclerotome development

description: Any process that modulates the rate, frequency, or extent of the progression of the sclerotome over time, from its initial formation to the mature structure. The sclerotome is the portion of the somite that will give rise to a vertebra.


name: positive regulation of vacuole fusion, non-autophagic

description: Any process that increases the frequency, rate or extent of the fusion of two vacuole membranes to form a single vacuole.


name: negative regulation of vacuole fusion, non-autophagic

description: Any process that decreases the frequency, rate or extent of the fusion of two vacuole membranes to form a single vacuole.


taste bud development

description: The progression of the taste bud over time, from its formation to the mature state. The taste bud is a specialized area of the tongue that contains taste receptors.


taste bud morphogenesis

description: The process in which the anatomical structures of the taste bud are generated and organized. The taste bud is a specialized area of the tongue that contains taste receptors.


taste bud formation

description: The developmental process pertaining to the initial formation of the taste bud from unspecified parts. The taste bud is a specialized area of the tongue that contains taste receptors.


fungiform papilla development

description: The progression of the fungiform papilla over time, from its formation to the mature structure. The fungiform papilla is a mushroom-shaped papilla of the tongue.


fungiform papilla morphogenesis

description: The process in which the anatomical structures of the fungiform papilla are generated and organized. The fungiform papilla is a mushroom-shaped papilla of the tongue.


fungiform papilla formation

description: The developmental process pertaining to the initial formation of a spongiform papilla from unspecified parts. The fungiform papilla is a mushroom-shaped papilla of the tongue.


name: striated muscle contraction involved in embryonic body morphogenesis

description: The process in which force is generated within striated embryonic muscle tissue, resulting in a contraction of the muscle that contributes to the formation of an embryo's characteristic body morphology.


name: clathrin-sculpted gamma-aminobutyric acid transport vesicle

description: A clathrin-sculpted lipid bilayer membrane-enclosed vesicle after clathrin release and containing gamma-aminobutyric acid transport vesicle.


name: clathrin-sculpted gamma-aminobutyric acid transport vesicle lumen

description: The volume enclosed by the membrane of the clathrin-sculpted gamma-aminobutyric acid transport vesicle.


name: clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane

description: The lipid bilayer surrounding a clathrin-sculpted gamma-aminobutyric acid transport vesicle.


name: striated muscle paramyosin thick filament assembly

description: The aggregation, arrangement and bonding together of proteins to form the paramyosin-based thick filaments of myofibrils in striated muscle.


name: paramyosin filament assembly or disassembly

description: The formation or disassembly of a filament composed of paramyosin molecules.


paramesonephric duct development

description: The process whose specific outcome is the progression of the paramesonephric duct over time, from its formation to the mature structure. Mullerian ducts (or paramesonephric ducts) are paired ducts of the embryo that run down the lateral sides of the urogenital ridge and terminate at the mullerian eminence in the primitive urogenital sinus. In the female, they will develop to form the fallopian tubes, uterus, cervix, and the upper portion of the vagina; in the male, they are lost. These ducts are made of tissue of mesodermal origin.


mesonephros morphogenesis

description: The process in which the anatomical structures of the mesonephros are generated and organized.


name: mesonephric juxtaglomerulus cell differentiation

description: The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the juxtaglomerulus cells of the mesonephros as it progresses from its formation to the mature state.


name: cell differentiation involved in mesonephros development

description: The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the mesonephros as it progresses from its formation to the mature state.


name: cell proliferation involved in mesonephros development

description: The multiplication or reproduction of cells, resulting in the expansion of the population in the mesonephros.


name: cell-cell signaling involved in mesonephros development

description: Any process that mediates the transfer of information from one cell to another and contributes to the progression of the mesonephros over time, from its formation to the mature organ.


mesonephric collecting duct development

description: The process whose specific outcome is the progression of a collecting duct in the mesonephros over time, from its formation to the mature structure. The collecting duct regulates water, electrolyte and acid-base balance. The collecting duct is the final common path through which urine flows before entering the ureter and then emptying into the bladder.


name: mesonephric juxtaglomerular apparatus development

description: The process whose specific outcome is the progression of the juxtaglomerular apparatus in the mesonephros over time, from its formation to the mature structure. The juxtaglomerular apparatus is an anatomical structure which consists of juxtaglomerular cells, extraglomerular mesangial cells and the macula densa. The juxtaglomerular apparatus lies adjacent to the glomerulus and regulates kidney function by maintaining the blood flow to the kidney and the filtration rate.


name: positive regulation of mesonephros development

description: Any process that increases the rate, frequency or extent of mesonephros development. Mesonephros development is the process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. The mesonephros is an organ that filters the blood and excretes the end products of body metabolism in the form of urine.


name: mesonephric smooth muscle tissue development

description: The process whose specific outcome is the progression of smooth muscle in the mesonephros over time, from its formation to the mature structure.


mesonephric nephron development

description: The process whose specific outcome is the progression of a nephron in the mesonephros over time, from its formation to the mature structure. A nephron is the functional unit of the kidney.


regulation of mesonephros development

description: Any process that modulates the rate, frequency or extent of mesonephros development. Mesonephros development is the process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. The mesonephros is an endocrine and metabolic organ that filters the blood and excretes the end products of body metabolism in the form of urine.


name: negative regulation of mesonephros development

description: Any process that decreases the rate, frequency or extent of mesonephros development. Mesonephros development is the process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. The mesonephros is an organ that filters the blood and excretes the end products of body metabolism in the form of urine.


mesonephric mesenchyme development

description: The biological process whose specific outcome is the progression of a mesonephric mesenchyme from an initial condition to its mature state. This process begins with the formation of mesonephric mesenchyme and ends with the mature structure. Mesonephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the mesonephros.


mesonephric macula densa development

description: The process whose specific outcome is the progression of the mesonephric macula densa over time, from its formation to the mature structure. The mesonephric macula densa is an area of specialized cells in the distal tubule of the mesonephros that makes contact with the vascular pole of the glomerulus.


mesonephric mesenchyme morphogenesis

description: The process in which the anatomical structures of a mesonephric mesenchymal tissue are generated and organized. Mesonephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the mesonephros.


name: mesonephric mesenchymal cell proliferation involved in mesonephros development

description: The multiplication or reproduction of cells, resulting in the expansion of a mesonephric mesenchymal cell population.


name: mesonephric mesenchymal cell differentiation

description: The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesenchymal cells of the mesonephros as it progresses from its formation to the mature state.


mesonephric glomerulus development

description: The progression of the mesonephric glomerulus over time from its initial formation until its mature state. The mesonephric glomerulus is a capillary tuft which forms a close network with the visceral epithelium (podocytes) and the mesangium to form the filtration barrier and is surrounded by Bowman's capsule in nephrons of the mature vertebrate kidney, or mesonephros.


name: mesonephric extraglomerular mesangial cell proliferation involved in mesonephros development

description: The multiplication or reproduction of extraglomerular glomerular mesangium cells in the mesonephros by cell division, resulting in the expansion of their population. Extraglomerular mesangial cells (also known as lacis cells, Goormaghtigh cells) are light-staining cells in the kidney found outside the glomerulus, near the vascular pole and macula densa.


name: proximal/distal pattern formation involved in mesonephric nephron development

description: The regionalization process in which specific areas of cell differentiation are determined along a proximal/distal axis of a nephron in the mesonephros. The proximal/distal axis is defined by a line that runs from the glomerulus (proximal end) outward toward the mesonephric duct (distal end).


name: pattern specification involved in mesonephros development

description: Any developmental process that results in the creation of defined areas or spaces within the mesonephros to which cells respond and eventually are instructed to differentiate.


mesonephric nephron morphogenesis

description: The process in which the anatomical structures of the mesonephric nephron are generated and organized. A mesonephric nephron is the functional unit of the mesonephros.


name: mesonephric juxtaglomerulus cell development

description: The process whose specific outcome is the progression of a mesonephric juxtaglomerulus cell over time, from its formation to the mature structure.


name: mesonephric juxtaglomerulus cell fate commitment

description: The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesonephric juxtaglomerulus cell.


name: mesonephric glomerulus vasculature development

description: The biological process whose specific outcome is the progression of a mesonephric glomerulus vasculature from an initial condition to its mature state. This process begins with the formation of the mesonephric glomerulus vasculature and ends with the mature structure. The mesonephric glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the mesonephric glomerulus.


name: mesonephric glomerular epithelium development

description: The process whose specific outcome is the progression of the mesonephric glomerular epithelium over time, from its formation to the mature structure. The mesonephric glomerular epithelium is an epithelial tissue that covers the outer surfaces of the glomerulus in the mesonephros. The mesonephric glomerular epithelium consists of both parietal and visceral epithelium. Mesonephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. A mesonephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the mesonephros.


name: mesonephric glomerular basement membrane development

description: The process whose specific outcome is the progression of the mesonephric glomerular basement membrane over time, from its formation to the mature structure. The mesonephric glomerular basement membrane is the basal laminal portion of the mesonephric glomerulus which performs the actual filtration.


mesonephric glomerulus morphogenesis

description: The process in which the anatomical structures of the mesonephric glomerulus are generated and organized. The mesonephric glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate mesonephros.


name: mesenchymal stem cell maintenance involved in mesonephric nephron morphogenesis

description: The process in which an organism retains a population of mesenchymal stem cells that contributes to the shaping of a nephron in the mesonephros. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells.


name: mesonephric comma-shaped body morphogenesis

description: The process in which the mesonephric comma-shaped body is generated and organized. The mesonephric comma-shaped body is the precursor structure to the mesonephric S-shaped body that contributes to the morphogenesis of a nephron in the mesonephros.


name: convergent extension involved in mesonephric nephron morphogenesis

description: The morphogenetic process in which the renal epithelium narrows along one axis and lengthens in a perpendicular axis that contributes to the shaping of a nephron in the mesonephros.


name: establishment of planar polarity involved in mesonephric nephron morphogenesis

description: Coordinated organization of groups of cells in the plane of an epithelium that contributes to the shaping of a nephron in the mesonephros.


name: mesenchymal stem cell differentiation involved in mesonephric nephron morphogenesis

description: The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal stem cell that contributes to the shaping of a nephronin the mesonephros. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells.


name: mesonephric nephron tubule morphogenesis

description: The process in which the anatomical structures of a mesonephric nephron tubule are generated and organized. A mesonephric nephron tubule is an epithelial tube that is part of the mesonephric nephron, the functional part of the mesonephros.


name: mesonephric nephron epithelium development

description: The process whose specific outcome is the progression of the mesonephric nephron epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The mesonephric nephron epithelium is a tissue that covers the surface of a nephron in the mesonephros.


mesonephric nephron tubule development

description: The progression of a mesonephric nephron tubule over time, from its initial formation to the mature structure. A mesonephric nephron tubule is an epithelial tube that is part of the mesonephric nephron, the functional part of the mesonephros.


mesonephric renal vesicle morphogenesis

description: The process in which the anatomical structures of the mesonephric renal vesicle are generated and organized. The renal vesicle is the primordial structure of the mesonephric nephron epithelium, and is formed by the condensation of mesenchymal cells.


mesonephric S-shaped body morphogenesis

description: The process in which the mesonephric S-shaped body is generated and organized. The mesonephric S-shaped body is the successor of the mesonephric comma-shaped body that contributes to the morphogenesis of a nephron in the mesonephros.


name: establishment or maintenance of bipolar cell polarity

description: Any cellular process that results in the specification, formation or maintenance of a bipolar intracellular organization or cell growth patterns.


name: establishment or maintenance of bipolar cell polarity regulating cell shape

description: Any cellular process that results in the specification, formation or maintenance of a bipolar intracellular organization or cell growth patterns that regulates the shaping of a cell.


name: mesonephric glomerular mesangium development

description: The process whose specific outcome is the progression of the mesonephric glomerular mesangium over time, from its formation to the mature structure. The mesonephric glomerular mesangium is the thin membrane connective tissue composed of mesangial cells in the mesonephros, which helps to support the capillary loops in a renal glomerulus.


name: mesonephric glomerulus vasculature morphogenesis

description: The process in which the anatomical structures of the mesonephric glomerulus vasculature are generated and organized. The mesonephric glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the mesonephric glomerulus.


name: mesonephric glomerular capillary formation

description: The process that gives rise to a mesonephric glomerular capillary. This process pertains to the initial formation of a structure from unspecified parts.


name: mesonephric glomerular epithelial cell differentiation

description: The process in which a relatively unspecialized cell acquires specialized features of a mesonephric glomerular epithelial cell. Mesonephric glomerular epithelial cells are specialized epithelial cells that form part of the mesonephric glomerulus; there are two types, mesonephric glomerular parietal epithelial cells and mesonephric glomerular visceral epithelial cells.


name: mesonephric glomerular epithelial cell development

description: The process whose specific outcome is the progression of a mesonephric glomerular epithelial cell over time, from its formation to the mature structure. Mesonephric glomerular epithelial cells are specialized epithelial cells that form part of the mesonephric glomerulus; there are two types, mesonephric glomerular parietal epithelial cells and mesonephric glomerular visceral epithelial cells.


name: mesonephric glomerular epithelial cell fate commitment

description: The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesonephric glomerular epithelial cell. Mesonephric glomerular epithelial cells are specialized epithelial cells that form part of the mesonephric glomerulus; there are two types, mesonephric glomerular parietal epithelial cells and mesonephric glomerular visceral epithelial cells.


name: mesonephric glomerular parietal epithelial cell differentiation

description: The process in which a relatively unspecialized cell acquires specialized features of a mesonephric glomerular parietal epithelial cell. Mesonephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport.


name: mesonephric glomerular parietal epithelial cell development

description: The process whose specific outcome is the progression of a mesonephric glomerular parietal epithelial cell over time, from its formation to the mature structure. Mesonephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport.


name: mesonephric glomerular parietal epithelial cell fate commitment

description: The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesonephric glomerular parietal epithelial cell. Mesonephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. These cells may also give rise to podocytes.


mesonephric podocyte differentiation

description: The process in which a relatively unspecialized cell acquires specialized features of a mesonephric glomerular visceral epithelial cell. A mesonephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the mesonephros.


mesonephric podocyte development

description: The process whose specific outcome is the progression of a mesonephric glomerular visceral epithelial cell over time, from its formation to the mature structure. A mesonephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the mesonephros.


name: mesonephric podocyte cell fate commitment

description: The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesonephric glomerular visceral epithelial cell. A mesonephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the mesonephros.


name: mesonephric glomerular mesangial cell differentiation

description: The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the glomerular mesangial cells of the mesonephros as it progresses from its formation to the mature state.


name: mesonephric mesangial cell differentiation

description: The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesangial cells of the mesonephros as it progresses from its formation to the mature state.


name: mesenchymal to epithelial transition involved in mesonephros morphogenesis

description: A transition where a mesenchymal cell establishes apical/basolateral polarity, forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the mesonephros.


mesonephric renal vesicle formation

description: The developmental process pertaining to the initial formation of the mesonephros.


name: mesonephric glomerular mesangial cell development

description: The process whose specific outcome is the progression of a glomerular mesangial cell in the mesonephros over time, from its formation to the mature structure.


name: mesonephric glomerular mesangial cell fate commitment

description: The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesonephric glomerular mesangial cell.


name: mesonephric nephron tubule epithelial cell differentiation

description: The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the mesonephric nephron tubule as it progresses from its formation to the mature state.


name: mesonephric interstitial fibroblast differentiation

description: The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the interstitial fibroblasts of the mesonephros as it progresses from its formation to the mature state.


name: mesonephric interstitial fibroblast development

description: The process whose specific outcome is the progression of a mesonephric interstitial fibroblast over time, from its formation to the mature structure.


name: mesonephric interstitial fibroblast fate commitment

description: The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesonephric interstitial fibroblast.


name: mesonephric glomerular mesangial cell proliferation involved in mesonephros development

description: The multiplication or reproduction of glomerular mesangial cells in the mesonephros, resulting in the expansion of the population.


name: mesonephric intraglomerular mesangial cell proliferation

description: The multiplication or reproduction of intraglomerular glomerular mesangium cells in the mesonephros by cell division, resulting in the expansion of their population. Intraglomerular mesangial cells are specialized pericytes located among the glomerular capillaries within a renal corpuscle of a kidney. They are required for filtration, structural support and phagocytosis.


name: mesenchymal to epithelial transition involved in mesonephric renal vesicle formation

description: A transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the mesonephric renal vesicle.


name: mesonephric connecting tubule development

description: The process whose specific outcome is the progression of the mesonephric connecting tubule over time, from its formation to the mature structure. The mesonephric connecting tubule is a tubular segment of the mesonephric nephron; it connects the distal tubule to the collecting duct in the mesonephros.


mesonephric distal tubule morphogenesis

description: The process in which the anatomical structures of a mesonephric distal tubule are generated and organized. The mesonephric distal tubule is a mesonephric nephron tubule that begins at the macula densa and extends to the mesonephric connecting tubule.


mesonephric distal tubule development

description: The process whose specific outcome is the progression of the mesonephric distal tubule over time, from its formation to the mature structure. The mesonephric distal tubule is a mesonephric nephron tubule that begins at the terminal segment of the proximal tubule and ends at the mesonephric connecting tubule.


mesonephric proximal tubule development

description: The progression of the mesonephric proximal tubule over time, from its formation to the mature structure. The mesonephric proximal tubule extends from the capsule to the distal tubule.


name: mesonephric proximal tubule morphogenesis

description: The process in which the anatomical structures of a mesonephric proximal tubule are generated and organized. The mesonephric proximal tubule extends from the capsule to the distal tubule.


mesonephric nephron tubule formation

description: The developmental process pertaining to the initial formation of a mesonephric nephron tubule from unspecified parts. A mesonephric nephron tubule is an epithelial tube that is part of a nephron in the mesonephros.


name: epithelial cell migration involved in mesonephric nephron tubule morphogenesis

description: The orderly movement of epithelial cells within a renal tubule that contributes to mesonephric nephron tubule morphogenesis.


name: epithelial cell migration involved in mesonephric distal tubule morphogenesis

description: The orderly movement of epithelial cells within a renal tubule that contributes to mesonephric distal tubule morphogenesis.


name: epithelial cell migration involved in mesonephric proximal tubule morphogenesis

description: The orderly movement of epithelial cells within a renal tubule that contributes to mesonephric proximal tubule morphogenesis.


name: specification of mesonephric connecting tubule identity

description: The process in which the connecting tubule of the mesonephric nephron acquires its identity.


name: specification of mesonephric nephron tubule identity

description: The process in which the tubules arranged along the proximal/distal axis of the mesonephric nephron acquire their identity.


name: specification of mesonephric distal tubule identity

description: The process in which the distal tubule of the mesonephric nephron acquires its identity.


name: specification of mesonephric proximal tubule identity

description: The process in which the proximal tubule of the mesonephric nephron acquires its identity.


mesonephric capsule development

description: The progression of the mesonephric capsule over time, from its formation to the mature structure. The mesonephric capsule is the tough fibrous layer surrounding the mesonephros, covered in a thick layer of perinephric adipose tissue.


mesonephric capsule morphogenesis

description: The process in which the anatomical structures of the mesonephric capsule are generated and organized. The mesonephric capsule is the tough fibrous layer surrounding the mesonephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage.


mesonephric capsule formation

description: The developmental process pertaining to the initial formation of a mesonephric capsule from unspecified parts. The mesonephric capsule is the tough fibrous layer surrounding the mesonephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage.


mesonephric capsule specification

description: The regionalization process in which the identity of the mesonephric capsule is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized.


mesonephric renal vesicle induction

description: Signaling at short range between cells of the ureteric bud terminus and the kidney mesenchyme that positively regulates the formation of the mesonephric renal vesicle.


name: regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis

description: Any process that modulates the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the mesonephros.


name: negative regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis

description: Any process that reduces the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the mesonephros.


name: positive regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis

description: Any process that increases the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the mesonephros.


name: retina vasculature development in camera-type eye

description: The process whose specific outcome is the progression of the vasculature of the retina over time, from its formation to the mature structure.


name: retina vasculature morphogenesis in camera-type eye

description: The process in which the vasculature of the retina is generated and organized.


cerebellum vasculature development

description: The process whose specific outcome is the progression of the vasculature of the cerebellum over time, from its formation to the mature structure.


cerebellum vasculature morphogenesis

description: The process in which the vasculature of the cerebellum is generated and organized.


smooth muscle cell-matrix adhesion

description: The binding of a smooth muscle cell to the extracellular matrix via adhesion molecules.


cornea development in camera-type eye

description: The progression of the cornea over time, from its formation to the mature structure. The cornea is the transparent structure that covers the anterior of the eye.


retinal blood vessel morphogenesis

description: The process whose specific outcome is the progression of a blood vessel of the retina over time, from its formation to the mature structure.


name: maintenance of bipolar cell polarity regulating cell shape

description: The maintenance of established bipolar anisotropic intracellular organization or cell growth patterns that results in the shaping of a cell.


name: cardiac neural crest cell differentiation involved in heart development

description: The process in which a relatively unspecialized cell acquires specialized features of a cardiac neural crest cell that will migrate to the heart and contribute to its development. Cardiac neural crest cells are specialized cells that migrate toward the heart from the third, fourth and sixth pharyngeal arches.


name: cardiac neural crest cell development involved in heart development

description: The process aimed at the progression of a cardiac neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell that contributes to the development of the heart.


name: cardiac neural crest cell development involved in outflow tract morphogenesis

description: The process aimed at the progression of a cardiac neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell that contributes to the shaping of the outflow tract.


name: cell surface receptor signaling pathway involved in heart development

category: biolink:Pathway biolink:OntologyClass biolink:BiologicalProcess biolink:Occurrent biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: The series of molecular signals initiated by a ligand the binding to its receptor on the surface of a cell, which contributes to the progression of the heart over time.


name: fibroblast growth factor receptor signaling pathway involved in heart development

description: The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands and contributing to the progression of the heart over time.


name: Notch signaling involved in heart development

description: The series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell and contributing to the progression of the heart over time.


name: canonical Wnt signaling pathway involved in heart development

description: The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that contributes to the progression of the heart over time. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes.


renal filtration cell differentiation

description: The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a renal filtration cell. Renal filtration cells are specialized cells of the renal system that filter fluids by charge, size or both. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.


nephrocyte differentiation

description: The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a nephrocyte. A nephrocyte is an insect renal cell that filters hemolymph. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.


pericardial nephrocyte differentiation

description: The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a pericardial nephrocyte. A pericardial nephrocyte is an insect renal cell that filters hemolymph and is found with other pericardial nephrocytes in two rows flanking the dorsal vessel. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.


garland nephrocyte differentiation

description: The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a garland nephrocyte. A garland nephrocyte is an insect renal cell that filters hemolymph and forms a ring with other garland nephrocytes around the esophagus. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.


disseminated nephrocyte differentiation

description: The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a disseminated nephrocyte. A disseminated nephrocyte is an insect renal cell that filters hemolymph and is found at scattered locations in the fat body or other tissues. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.


name: cell proliferation involved in heart morphogenesis

description: The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to the shaping of the heart.


name: cell proliferation involved in outflow tract morphogenesis

description: The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to the shaping of the outflow tract.


renal tubule development

description: The progression of the renal tubule over time from its formation to the mature form. A renal tubule is a tube that filters, re-absorbs and secretes substances to rid an organism of waste and to play a role in fluid homeostasis.


anterior Malpighian tubule development

description: The process whose specific outcome is the progression of the anterior Malpighian tubule over time, from its formation to the mature structure. The pair of anterior tubules arise from a dorsal region of the embryonic hindgut and projects forwards through the body cavity. A Malpighian tubule is a fine, thin-walled excretory tubule in insects which connects with the posterior part of the gut.


posterior Malpighian tubule development

description: The process whose specific outcome is the progression of the posterior Malpighian tubule over time, from its formation to the mature structure. The pair of posterior tubules arise from a ventrolateral region of the embryonic hindgut and project backwards through the body cavity. A Malpighian tubule is a fine, thin-walled excretory tubule in insects which connects with the posterior part of the gut.


name: Malpighian tubule principal cell differentiation

description: The process in which a relatively unspecialized cell acquires specialized features of a Malpighian tubule principal cell. A Malpighian tubule principal cell is an epithelial secretory cell that transports cations into the lumen of the tubule.


name: Malpighian tubule stellate cell differentiation

description: The process in which a relatively unspecialized cell acquires specialized features of a Malpighian tubule stellate cell. A Malpighian tubule stellate cell is a specialized epithelial secretory cell that moves chloride ions and water across the tubule epithelium.


name: epithelial cell proliferation involved in Malpighian tubule morphogenesis

description: The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population and contributing to the shaping of a Malpighian tubule.


Malpighian tubule bud morphogenesis

description: The morphogenetic process in which a bud forms from the embryonic hindgut tube to form the Malpighian tubule. A bud is a protrusion that forms from the tube by localized changes in cell shape and position.


renal tubule morphogenesis

description: The process in which the renal tubule is generated by specification of cell fate, through the maintenance of cell polarity, regulated cell proliferation and morphogenetic cell rearrangements, shape changes and growth. A renal tubule is a tube that filters, re-absorbs and secretes substances to rid an organism of waste and to play a role in fluid homeostasis.


name: cell rearrangement involved in Malpighian tubule morphogenesis

description: The movement of an epithelial cell with respect to other epithelial cells that contributes to the shaping of the Malpighian tubule.


name: cell growth involved in Malpighian tubule morphogenesis

description: The growth of an epithelial cell dependent on cycles of endoreplication, where growth contributes to the shaping of the Malpighian tubule.


name: cell morphogenesis involved in Malpighian tubule morphogenesis

description: The shape change of an epithelial cell from a columnar to squamous cell morphology that contributes to the shaping of the Malpighian tubule.


cardiac conduction

description: Transfer of an organized electrical impulse across the heart to coordinate the contraction of cardiac muscles. The process begins with generation of an action potential (in the sinoatrial node (SA) in humans) and ends with a change in the rate, frequency, or extent of the contraction of the heart muscles.


name: establishment or maintenance of monopolar cell polarity

description: Any cellular process that results in the specification, formation or maintenance of monopolar intracellular organization or cell growth patterns. Monopolar cell organization is directional organization along an axis.


name: establishment or maintenance of monopolar cell polarity regulating cell shape

description: Any cellular process that results in the specification, formation or maintenance of a monopolar intracellular organization or cell growth patterns that regulate the shape of a cell.


name: non-canonical Wnt signaling pathway involved in heart development

description: The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via effectors other than beta-catenin and contributing to the progression of the heart over time.


name: cell adhesion involved in heart morphogenesis

description: The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules that contributes to the shaping of the heart.


name: regulation of cell adhesion involved in heart morphogenesis

description: Any process that modulates the extent of cell adhesion contributing to the shaping of the heart.


name: planar cell polarity pathway involved in cardiac muscle cell fate commitment

description: The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via effectors other than beta-catenin and contributing to a cardioblast being committed to a cardiac muscle cell fate.


name: planar cell polarity pathway involved in heart morphogenesis

description: The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity that contributes to the shaping of the heart.


name: planar cell polarity pathway involved in outflow tract morphogenesis

description: The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity that contributes to the shaping of the outflow tract.


name: planar cell polarity pathway involved in ventricular septum morphogenesis

description: The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity that contributes to the shaping of the ventricular septum.


name: planar cell polarity pathway involved in cardiac right atrium morphogenesis

description: The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity that contributes to the shaping of the cardiac right atrium.


name: planar cell polarity pathway involved in cardiac muscle tissue morphogenesis

description: The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity that contributes to the shaping of the cardiac muscle tissue.


neural precursor cell proliferation

description: The multiplication or reproduction of neural precursor cells, resulting in the expansion of a cell population. A neural precursor cell is either a nervous system stem cell or a nervous system progenitor cell.


name: cell chemotaxis involved in Malpighian tubule morphogenesis

description: The directed movement of the outgrowing Malpighian tubule guided by specific chemical cues/signals. Movement may be towards a guidance cue (positive chemotaxis) or away from it (negative chemotaxis). Guidance contributes to the final positioning of the tubule.


name: planar cell polarity pathway involved in pericardium morphogenesis

description: The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity that contributes to the shaping of the pericardium.


Wnt protein secretion

description: The controlled release of a Wnt protein from a cell.


regulation of Wnt protein secretion

description: Any process that modulates the frequency, rate or extent of the controlled release of a Wnt protein from a cell.


name: positive regulation of Wnt protein secretion

description: Any process that activates or increases the frequency, rate or extent of the controlled release of a Wnt protein from a cell.


name: negative regulation of Wnt protein secretion

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of a Wnt protein from a cell.


optic chiasma development

description: The developmental process pertaining to the progression of the optic chiasm from its initial formation to the mature structure. The process begins when the pathfinding of the axons of the developing optic nerve cause some axons to cross at the midline of the brain and ends when the axons are mature.


name: positive regulation of maintenance of bipolar cell polarity regulating cell shape

description: Any process that increases the frequency, rate or extent of maintenance of bipolar cell polarity regulating cell shape.


name: negative regulation of maintenance of bipolar cell polarity regulating cell shape

description: Any process that decreases the frequency, rate or extent of maintenance of bipolar cell polarity regulating cell shape.


name: negative regulation of progesterone biosynthesis involved in luteolysis

description: Any process that decreases the rate, frequency or extent of the biosynthesis of progesterone biosynthesis that contributes to luteolysis.


name: apoptotic process involved in luteolysis

description: The apoptotic process that contributes to luteolysis.


name: positive regulation of triglyceride lipase activity

description: Any process that increases the activity of triglyceride lipase.


behavioral response to chemical pain

description: Any process that results in a change in the behaviour of an organism as a result of a chemical pain stimulus.


name: behavioral response to acetic acid induced pain

description: Any process that results in a change in the behaviour of an organism as a result of an acetic acid pain stimulus.


name: behavioral response to formalin induced pain

description: Any process that results in a change in the behaviour of an organism as a result of a formalin pain stimulus.


name: negative regulation of testicular blood vessel morphogenesis

description: Any process that stops, prevents, or reduces the frequency, rate or extent of blood vessel morphogenesis in the testicle.


testosterone biosynthetic process

description: The chemical reactions and pathways resulting in the formation of testosterone, an androgen having 17beta-hydroxy and 3-oxo groups, together with unsaturation at C-4 C-5.


name: determination of heart left/right asymmetry

description: Determination of the asymmetric location of the heart with respect to the left and right halves of the organism.


mammillary axonal complex development

description: The progression of the mammillary axonal complex over time, from its formation to the mature structure. The mammillary axonal complex is formed by the axons from the lateral, medial mammillary and the dorsal premammillary nuclei which share a branching pattern. Every neuron gives off one axonal stem that bifurcates into 2 branches. One of the branches is directed dorsally to the thalamus and another caudally to the midbrain.


name: mammillothalamic axonal tract development

description: The progression of the mammillothalamic axonal tract, from its formation to the mature structure. The mammillothalamic tract is the collection of axons that connects the two major subdivisions of the diencephalon (hypothalamus and thalamus) and closes the diencephalic circuit.


mammillotectal axonal tract development

description: The progression of the mammillotectal tract over time, from its formation to the mature structure. The mammillotectal tract is the collection of axons that connects the ventral diencephalon to the superior colliculus.


name: mammillotegmental axonal tract development

description: The process in which the mammillotegmental tract progresses over time, from its formation to the mature structure. The mammillotegmental tract is the collection of axons that connects the ventral diencephalon to the tegmentum and pons.


mammary gland lobule development

description: The progression of the mammary gland lobule over time, from its formation to the mature structure. A mammary gland lobule is a small rounded projection of the mammary gland.


corpora quadrigemina development

description: The progression of the corpora quadrigemina over time, from its formation to the mature structure. The corpora quadrigemina is a part of the midbrain that is made up of the superior and inferior colliculi.


inferior colliculus development

description: The process whose specific outcome is the progression of the inferior colliculus over time, from its formation to the mature structure. The inferior colliculus (IC) (Latin, lower hill) is the principal midbrain nucleus of the auditory pathway and receives input from several more peripheral brainstem nuclei in the auditory pathway, as well as inputs from the auditory cortex. The inferior colliculus has three subdivisions: the central nucleus (CIC), a dorsal cortex (DCIC) by which it is surrounded, and an external cortex (ICX) which is located laterally.


superior colliculus development

description: The process whose specific outcome is the progression of the superior colliculus over time, from its formation to the mature structure. The superior colliculus is also known as the optic tectum or simply tectum and is a paired structure that forms a major component of the vertebrate midbrain.


cell migration in diencephalon

description: The orderly movement of a cell that will reside in the diencephalon.


name: Malpighian tubule tip cell differentiation

description: The process in which a relatively unspecialized cell acquires specialized features of a Malpighian tubule tip cell. A Malpighian tubule tip cell is a mitogenic signaling cell that controls the proliferation of its neighboring cells.


trabecula morphogenesis

description: The process of shaping a trabecula in an organ. A trabecula is a small, often microscopic, tissue element in the form of a small beam, strut or rod, which generally has a mechanical function. Trabecula are usually but not necessarily, composed of dense collagenous tissue.


heart trabecula morphogenesis

description: The process of shaping a trabecula in the heart. A trabecula is a small, often microscopic, tissue element in the form of a small beam, strut or rod, which generally has a mechanical function. Trabecula are usually but not necessarily, composed of dense collagenous tissue.


name: fibroblast proliferation involved in heart morphogenesis

description: The multiplication or reproduction of fibroblasts, resulting in the expansion of a fibroblast population that contributes to the shaping of the heart.


closure of optic fissure

description: The closure of the temporary ventral gap in the optic cup that contributes to its shaping.


regulation of extent of cell growth

description: Any process that modulates the extent of cell growth.


regulation of rate of cell growth

description: Any process that modulates the rate of cell growth.


regulation of direction of cell growth

description: Any process that modulates the direction of cell growth.


name: positive regulation of direction of cell growth

description: Any process that increases the direction of cell growth.


name: negative regulation of direction of cell growth

description: Any process that decreases the direction of cell growth.


name: regulation of transcription from RNA polymerase II promoter by a nonfermentable carbon source

description: A transcription regulation process in which the presence of a nonfermentable carbon source leads to the modulation of the frequency, rate, or extent of transcription, from an RNA polymerase II promoter, of specific genes involved in the metabolism of other carbon sources.


name: positive regulation of transcription from RNA polymerase II promoter by a nonfermentable carbon source

description: A transcription regulation process in which the presence of a nonfermentable carbon source leads to an increase of the frequency, rate, or extent of transcription, from an RNA polymerase II promoter, of specific genes involved in the metabolism of other carbon sources.


name: negative regulation of transcription from RNA polymerase II promoter by a nonfermentable carbon source

description: A transcription regulation process in which the presence of a nonfermentable carbon source leads to a decrease of the frequency, rate, or extent of transcription, from an RNA polymerase II promoter, of specific genes involved in the metabolism of other carbon sources.


name: positive regulation of transcription from RNA polymerase II promoter by oleic acid

description: Any process involving oleic acid that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.


bone trabecula morphogenesis

description: The process of shaping a trabecula in bone. A trabecula is a tissue element in the form of a small beam, strut or rod.


cellular response to methionine

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methionine stimulus.


name: cellular response to caloric restriction

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a of caloric restriction, insufficient food energy intake.


name: positive regulation of transcription from a mobile element promoter

description: Any process that activates or increases the frequency, rate or extent of transcription from a mobile element promoter.


establishment of skin barrier

description: Establishment of the epithelial barrier, the functional barrier in the skin that limits its permeability.


renal system vasculature development

description: The process whose specific outcome is the progression of vasculature of the renal system over time, from its formation to the mature structure.


renal system vasculature morphogenesis

description: The process in which the renal system vasculature is generated and organized. Morphogenesis pertains to the creation of form.


kidney vasculature morphogenesis

description: The process in which the kidney vasculature is generated and organized. Morphogenesis pertains to the creation of form.


kidney vasculature development

description: The process whose specific outcome is the progression of the vasculature of the kidney over time, from its formation to the mature structure.


renal artery morphogenesis

description: The process in which the anatomical structure of a renal artery is generated and organized. Renal arteries supply the kidneys with blood.


cardiac muscle cell fate determination

description: The process involved in cardiac muscle cell fate commitment. Once determination has taken place, a cell becomes committed to differentiate down a particular pathway regardless of its environment.


name: endocardial cushion cell differentiation

description: The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of an endocardial cushion cell.


endocardial cushion cell development

description: The process whose specific outcome is the progression of an endocardial cushion cell over time, from its formation to the mature state.


name: endocardial cushion cell fate commitment

description: The commitment of a cell to an endocardial cushion cell fate and its capacity to differentiate into an endocardial cushion cell.


name: endocardial cushion cell fate determination

description: The process involved in endocardial cushion cell fate commitment. Once determination has taken place, a cell becomes committed to differentiate down a particular pathway regardless of its environment.


name: endocardial cushion cell fate specification

description: The process involved in the specification of endocardial cushion cell identity. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment.


connective tissue development

description: The progression of a connective tissue over time, from its formation to the mature structure.


olfactory bulb tufted cell development

description: The process whose specific outcome is the progression of an olfactory bulb tufted cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.


trophoblast cell migration

description: Trophoblast cell migration that is accomplished by extension and retraction of a pseudopodium. Trophoblast cells line the outside of the blastocyst.


retrotrapezoid nucleus development

description: The progression of the retrotrapezoid nucleus (RTN) over time from it's initial formation to its mature state. The retrotrapezoid nucleus is a group of neurons in the rostral medulla, which are responsible regulating respiration.


name: retrotrapezoid nucleus neuron differentiation

description: The process in which a relatively unspecialized cell acquires specialized features of a neuron whose cell body resides in the retrotrapezoid nucleus.


name: interstitial cell of Cajal differentiation

description: The process in which a relatively unspecialized cell acquires specialized features of an interstitial cell of Cajal. An interstitial cell of Cajal is an intestinal neuroepithelial cell that serves as a pacemaker to trigger gut contraction.


name: release of sequestered calcium ion into cytosol by Golgi

description: The directed movement of calcium ions (Ca2+) out of the Golgi apparatus into the cytosol.


name: mesenchymal stem cell migration involved in uteric bud morphogenesis

description: The orderly movement of a mesenchymal stem cell from one site to another contributing to the shaping of the ureteric bud. A mesenchymal stem cell, or MSC, is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells.


name: mesonephric cell migration involved in male gonad development

description: The orderly movement of a cell from the mesonephros to the male gonad, contributing to its development.


reproductive system development

description: The progression of the reproductive system over time from its formation to the mature structure. The reproductive system consists of the organs that function in reproduction.


name: L-arginine transmembrane transporter activity

description: Enables the transfer of L-arginine from one side of a membrane to the other.


protein localization to lysosome

description: A process in which a protein is transported to, or maintained in, a location within a lysosome.


description: Catalysis of the reaction O-acetyl-ADP-ribose + H2O = ADP-ribose + acetate.


karyomere

description: A membrane-bound intermediate cleavage-stage structure of individual or groups of chromosomes that coalesces and fuses with other karyomeres to form a nucleus during interphase. Karyomere formation occurs in blastomeres undergoing rapid cell division.


name: regulation of type B pancreatic cell proliferation

description: Any process that modulates the frequency, rate or extent of type B pancreatic cell proliferation.


name: T follicular helper cell differentiation

description: The process in which a relatively unspecialized T cell acquires specialized features of a mature T follicular helper cell.


karyomere assembly

description: The process where the nuclear membrane engulfs condensed chromosomes to form karyomeres during M phase of the mitotic cell cycle.


karyomere membrane fusion

description: Process whereby karyomere membranes fuse during interphase to form a single lobed nucleus.


name: murein tripeptide carboxypeptidase activity

description: Catalysis of the reaction L-Ala-gamma-D-Glu-meso-Dap (murein tripeptide) + H2O = L-Ala-gamma-D-Glu + meso-diaminopimelate.


phagolysosome membrane

description: The lipid bilayer surrounding a phagolysosome.


cytosolic valyl-tRNA aminoacylation

description: The process of coupling valine to valyl-tRNA in the cytosol, catalyzed by valyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.


response to anticoagulant

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an anticoagulant stimulus.


response to aromatase inhibitor

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aromatase inhibitor stimulus.


name: response to platelet aggregation inhibitor

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a platelet aggregation inhibitor stimulus.


name: response to reverse transcriptase inhibitor

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reverse transcriptase inhibitor stimulus.


response to asparaginase

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an asparaginase stimulus.


response to TNF agonist

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a TNF agonist stimulus.


response to irinotecan

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an irinotecan stimulus.


sulfinylpropanyl adenylate synthase

description: Catalysis of the reaction: cysteine sulfanate + GTP + IMP = sulfinylpropanyl adenylate + GDP + 3 H+ + phosphate.


hematopoietic stem cell homeostasis

description: Any biological process involved in the maintenance of the steady-state number of hematopoietic stem cells within a population of cells.


memory T cell proliferation

description: The expansion of a memory T cell population by cell division.


name: high-affinity fructose transmembrane transporter activity

description: Enables the transfer of fructose from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.


name: asymmetric protein localization to old or new spindle pole body

description: Any process in which a protein is transported to, or maintained to either the old or new spindle pole body resulting in its being distributed asymmetrically.


name: central plaque of mitotic spindle pole body

description: One of three laminate structures that form the mitotic spindle pole body; the inner plaque is on the nuclear face of the spindle pole body.


name: half bridge of mitotic spindle pole body

description: Structure adjacent to the plaques of the mitotic spindle pole body.


name: inner plaque of mitotic spindle pole body

description: One of three laminate structures that form the mitotic spindle pole body; the inner plaque is in the nucleus.


name: intermediate layer of mitotic spindle pole body

description: Structure between the central and outer plaques of the mitotic spindle pole body.


name: outer plaque of mitotic spindle pole body

description: One of three laminate structures that form the mitotic spindle pole body; the outer plaque is in the cytoplasm.


2',3'-cyclic GMP-AMP synthase activity

description: Catalysis of the reaction: ATP + GTP = 2 diphosphate + cyclic G-P(2'-5')A-P(3'-5') (cyclic 2',3' GAMP).


name: early endosome to recycling endosome transport

description: The directed movement of substances, in membrane-bounded vesicles, from the early sorting endosomes to the recycling endosomes.


description: Catalysis of the ATP-dependent dehydration of t6A to form cyclic t6A.


name: cyclic threonylcarbamoyladenosine biosynthetic process

description: The chemical reactions and pathways resulting in the formation of cyclic threonylcarbamoyladenosine, a modified nucleoside found in some tRNA molecules.