description: Catalysis of the reaction: 1,3-alpha-D-mannosyl-1,2-alpha-D-mannosyl-1,2-alpha-D-mannosyl-D-mannose + UDP-N-acetyl-D-glucosamine = 1,3-alpha-D-mannosyl-1,2-(N-acetyl-alpha-D-glucosaminyl-alpha-D-mannosyl)-1,2-alpha-D-mannosyl-D-mannose + UDP.


category: biolink:MolecularActivity biolink:Occurrent biolink:OntologyClass biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: Catalysis of the reaction: beta-D-galactosyl-1,3-(N-acetyl-D-glucosaminyl-1,6)-N-acetyl-D-galactosaminyl-R + UDP-N-acetyl-D-glucosamine = N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,3-(N-acetyl-beta-D-glucosaminyl-1,6)-N-acetyl-D-galactosaminyl-R + UDP.


description: Catalysis of the reaction: 3-O-N-acetyl-D-galactosalaminyl-[protein] + UDP-N-acetyl-D-glucosamine = 3-O-N-acetyl-beta-D-glucosaminyl-1,3-N-acetyl-D-galactosaminyl-[protein] + UDP. Linkage of the glycan to the protein occurs via the oxygen atom in the side chain of an L-serine or L-threonine residue.


description: Catalysis of the reaction: N-acetyl-beta-D-glucosaminyl-1,3-N-acetyl-D-galactosaminyl-R + UDP-N-acetyl-D-glucosamine = N-acetyl-beta-D-glucosaminyl-1,6-(N-acetyl-beta-D-glucosaminyl-1,3)-N-acetyl-D-galactosaminyl-R + UDP.


description: Catalysis of the reaction: 1L-1-O-(indol-3-yl)acetyl-myo-inositol + UDP-D-galactose = 5-O-(indol-3-ylacetyl)-myo-inositol D-galactoside + H+ + UDP.


description: Catalysis of the reaction: a 1,2-diacyl-sn-glycerol + UDP-alpha-D-glucose = a 1,2-diacyl-3-O-(alpha-D-glucopyranosyl)-sn-glycerol + H+ + UDP.


description: Catalysis of the reaction: 13-hydroxydocosanoate + UDP-D-glucose = 13-beta-D-glucosyloxydocosanoate + UDP.


description: Catalysis of the reaction: flavonol 3-O-D-glucoside + UDP-L-rhamnose = flavonol 3-O-L-rhamnosylglucoside + UDP.


description: Catalysis of the reaction: pyridoxine + UDP-D-glucose = 5'-O-beta-D-glucosylpyridoxine + H+ + UDP.


description: Catalysis of the reaction: N-acetylneuraminyl-2,3-alpha-D-galactosyl-1,4-beta-D-glucosylceramide + UDP-N-acetylgalactosamine = N-acetyl-beta-D-galactosaminyl-1,4-(N-acetyl-alpha-neuraminyl-2,3)-beta-D-galactosyl-1,4-beta-D-glucosylceramide + UDP.


description: Catalysis of the reaction: 2 raffinose = sucrose + 1F-alpha-D-galactosylraffinose.


description: Catalysis of the reaction: sucrose + UDP-galactose = 6F-alpha-D-galactosylsucrose + UDP.


description: Catalysis of the reaction: methylazoxymethanol + UDP-D-glucose = H+ + cycasin + UDP.


description: Catalysis of the reaction: D-glucuronyl-1,3-beta-D-galactosylproteoglycan + UDP-N-acetylgalactosamine = N-acetyl-D-galactosaminyl-1,4-beta-D-glucuronyl-1,3-beta-D-galactosylproteoglycan + UDP.


description: Catalysis of the reaction: D-glucuronyl-N-acetyl-1,3-beta-D-galactosaminylproteoglycan + UDP-N-acetylgalactosamine = N-acetyl-D-galactosaminyl-1,4-beta-D-glucuronyl-N-acetyl-1,3-beta-D-galactosaminylproteoglycan + UDP.


description: Catalysis of the reaction: 4-hydroxymandelonitrile + UDP-D-glucose = H+ + taxiphyllin + UDP.


description: Catalysis of the reaction: D-galactosyl-(1->4)-beta-D-glucosyl-R + UDP-D-galactose = D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-R + H+ + UDP.


description: Catalysis of the reaction: lipopolysaccharide + UDP-N-acetylmannosaminouronate = N-acetyl-beta-D-mannosaminouronosyl-1,4-lipopolysaccharide + UDP.


description: Catalysis of the reaction: a hydroxyanthraquinone + UDP-D-glucose = a glucosyloxyanthraquinone + UDP.


description: Catalysis of the reaction: a flavanone + UDP-D-glucose = a flavanone 7-O-beta-D-glucoside + UDP.


description: Catalysis of the reaction: N-acetyl-D-glucosaminyldiphosphoundecaprenol + UDP-N-acetyl-D-mannosamine = N-acetyl-beta-D-mannosaminyl-1,4-N-acetyl-D-glucosaminyldiphosphoundecaprenol + UDP.


description: Catalysis of the reaction: N-acetyl-D-glucosaminyldiphosphoundecaprenol + UDP-D-glucose = beta-D-glucosyl-1,4-N-acetyl-D-glucosaminyldiphosphoundecaprenol + UDP.


description: Catalysis of the reaction: luteolin 7-O-beta-D-glucosiduronate + UDP-alpha-D-glucuronate = H+ + luteolin 7-O-[(beta-D-glucosiduronate)-(1->2)-(beta-D-glucosiduronate)] + UDP.


description: Catalysis of the reaction: luteolin 7-O-[(beta-D-glucosiduronate)-(1->2)-(beta-D-glucosiduronate)] + UDP-alpha-D-glucuronate = H+ + luteolin 7-O-[(beta-D-glucosiduronate)-(1->2)-(beta-D-glucosiduronate)] 4'-O-beta-D-glucosiduronate + UDP.


description: Catalysis of the reaction: nuatigenin + UDP-D-glucose = H+ + nuatigenin 3-beta-D-glucopyranoside + UDP.


description: Catalysis of the reaction: (25S)-5beta-spirostan-3beta-ol + UDP-D-glucose = (25S)-5beta-spirostan-3beta-yl beta-D-glucoside + H+ + UDP.


description: Catalysis of the reaction: 4-hydroxybenzoate + UDP-D-glucose = 4-(beta-D-glucosyloxy)benzoate + H+ + UDP.


description: Catalysis of the reaction: phenylthioacetohydroximate + UDP-D-glucose = desulfoglucotropeolin + UDP.


description: Catalysis of the reaction: (1->6)-alpha-D-mannosyloligosaccharide + beta-D-mannosylphosphodecaprenol = (1->6)-alpha-D-mannosyl-(1->6)-alpha-D-mannosyl-oligosaccharide + decaprenol phosphate.


description: Catalysis of the reaction: N-acetyl-beta-D-glucosaminyl-1,6-beta-D-(N-acetyl-B-glucosaminyl-1,2)-beta-D-mannosyl-R + UDP-N-acetyl-D-glucosamine = N-acetyl-beta-D-glucosaminyl-1,6-beta-D-(N-acetyl-D-glucosaminyl-1,2-beta)-(N-acetyl-D-glucosaminyl-1,4-beta)-D-mannosyl-R + UDP.


description: Catalysis of the reaction: 2,4-dihydroxy-7-methoxy-2H-1,4-benzoxazin-3(4H)-one + UDP-D-glucose = 2,4-dihydroxy-7-methoxy-2H-1,4-benzoxazin-3(4H)-one 2-D-glucoside + UDP.


description: Catalysis of the reaction: galactogen + UDP-galactose = 1,6-beta-D-galctosylgalactogen + UDP.


description: Catalysis of the reaction: a beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E)) + UDP-N-acetyl-alpha-D-glucosamine = a beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E)) + H+ + UDP.


name: diglucosyl diacylglycerol synthase activity

description: Catalysis of the reaction: 1,2-diacyl-3-O-(alpha-D-glucopyranosyl)-sn-glycerol + UDP-D-glucose = UDP + 1,2-diacyl-3-O-(alpha-D-glucopyranosyl(1,2)-O-alpha-D-glucopyranosyl)-sn-glycerol.


description: Catalysis of the reaction: sphingosine + UDP-D-galactose = H+ + psychosine + UDP.


description: Catalysis of the reaction: glucomannan(n) + GDP-mannose = glucomannan(n+1) + GDP.


name: alpha,alpha-trehalose-phosphate synthase (GDP-forming) activity

description: Catalysis of the reaction: GDP-D-glucose + glucose-6-phosphate = alpha,alpha-trehalose 6-phosphate + GDP.


description: Catalysis of the reaction: estradiol-17alpha 3-D-glucuronoside + UDP-N-acetyl-alpha-D-glucosamine = 17alpha-(N-acetyl-D-glucosaminyl)-estradiol 3-D-glucuronoside + H+ + UDP.


description: Catalysis of the reaction: UDP-D-galacturonate + 1,4-alpha-D-galacturonosyl(n) = 1,4-alpha-D-galacturonosyl(n+1) + UDP.


description: Catalysis of the reaction: heteroglycan + GDP-mannose = alpha-D-mannosylheteroglycan + GDP.


description: Catalysis of the reaction: poly(glycerol phosphate) + UDP-D-glucose = alpha-D-glucosylpoly(glycerol phosphate) + UDP.


description: Catalysis of the reaction: poly(ribitol phosphate) + UDP-D-glucose = beta-D-glucosylpoly(ribitol phosphate) + UDP.


description: Catalysis of the reaction: GDP-mannose + undecaprenyl phosphate = GDP + D-mannosyl-1-phosphoundecaprenol.


description: Catalysis of the reaction: raffinose + 1-alpha-D-galactosyl-myo-inositol = stachyose + myo-inositol.


description: Catalysis of the reaction: poly(ribitol phosphate) + UDP-N-acetyl-D-glucosamine = N-acetyl-D-glucosaminyl-poly(ribitol phosphate) + UDP.


name: lipopolysaccharide glucosyltransferase II activity

description: Catalysis of the reaction: lipopolysaccharide + UDP-D-glucose = D-glucosyl-lipopolysaccharide + UDP.


description: Catalysis of the reaction: glycosaminoglycan + UDP-galactose = D-galactosylglycosaminoglycan + UDP.


description: Catalysis of the reaction: polyprenyl phosphate + UDP-D-glucose = polyprenylphosphate-glucose + UDP.


description: Catalysis of the reaction: UDP-N-acetyl-D-galactosamine + alpha-D-galactosyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosylceramide = UDP + beta-N-acetyl-D-galactosaminyl-(1->3)-alpha-D-galactosyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosylceramide.


description: Catalysis of the reaction: sucrose + 1-alpha-D-galactosyl-myo-inositol = raffinose + myo-inositol.


description: Catalysis of the reaction: N-acetyl-D-glucosaminyl-(1,3)-D-galactosyl-(1,4)-D-glucosylceramide + UDP-galactose = D-galactosyl-N-acetyl-D-glucosaminyl-(1,3)-D-galactosyl-(1,4)-D-glucosylceramide + UDP.


description: Catalysis of the reaction: beta-D-galactosyl-(1,4)-beta-N-acetyl-D-glucosaminyl-R + UDP-galactose = alpha-D-galactosyl-(1,3)-beta-D-galactosyl-(1,4)-beta-N-acetyl-D-glucosaminyl-R + UDP.


description: Catalysis of the reaction: N-acetyl-D-galactosaminyl-(1,3)-D-galactosyl-(1,4)-D-galactosyl-(1,4)-D-glucosylceramide + UDP-N-acetylgalactosamine = N-acetyl-D-galactosaminyl-N-acetyl-D-galactosaminyl-(1,3)-D-galactosyl-(1,4)-D-galactosyl-(1,4)-D-glucosylceramide + UDP.


description: Catalysis of the reaction: 2 bilirubin-glucuronoside = bilirubin + bilirubin-bisglucuronoside.


description: Catalysis of the reaction: sn-glycerol 3-phosphate + UDP-D-galactose = 1-O-alpha-D-galactosyl-sn-glycerol 3-phosphate + H+ + UDP.


description: Catalysis of the reaction: diphosphate + nicotinamide mononucleotide = 5-phospho-alpha-D-ribose 1-diphosphate + H+ + nicotinamide.


description: Catalysis of the reaction: pyrophosphate + a 2,4-dioxotetrahydropyrimidine D-ribonucleotide = PRPP + a 2,4-dioxotetrahydropyrimidine.


description: Catalysis of the reaction: dTDP-L-dihydrostreptose + streptidine 6-phosphate = O-(1->4)-alpha-L-dihydrostreptosyl-streptidine 6-phosphate + dTDP + H+.


description: Catalysis of the reaction: dolichol-phosphate + UDP-D-xylose = dolichyl D-xylosyl phosphate + UDP.


description: Catalysis of the reaction: dolichyl D-xylosyl phosphate + protein = dolichol-phosphate + D-xylosylprotein.


description: Catalysis of the reaction: flavonol 3-O-glycoside + UDP-D-xylose = flavonol 3-O-D-xylosylglycoside + UDP.


description: Catalysis of the reaction: peptide diphthamide + NAD+ = peptide N-(ADP-D-ribosyl)diphthamide + niacinamide.


description: Catalysis of the reaction: beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminyl derivative + CMP-N-acetyl-beta-neuraminate = N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminyl derivative + CMP + H+.


description: Catalysis of the reaction: 1,2-diacyl-3-beta-D-galactosyl-sn-glycerol + CMP-N-acetyl-beta-neuraminate = 1,2-diacyl-3-[3-(alpha-D-N-acetylneuraminyl)-beta-D-galactosyl]-sn-glycerol + CMP + H+.


description: Catalysis of the reaction: alpha-N-acetylneuraminyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-D-galactosaminyl-R + CMP-N-acetyl-beta-neuraminate = alpha-N-acetylneuraminyl-(2->3)-beta-D-galactosyl-(1->3)-[N-acetyl-alpha-neuraminyl-(2->6)]-N-acetyl-D-galactosaminyl-R + CMP.


description: Catalysis of the reaction: cytolipin-H + CMP-N-acetylneuraminate = alpha-N-acetylneuraminyl-2,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide + CMP. Alpha-N-acetylneuraminyl-2,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide is also known as GM3.


description: Catalysis of the reaction: (6AS,11AS)-3,6A,9-trihydroxypterocarpan + dimethylallyl-pyrophosphate = glyceollin + diphosphate.


description: Catalysis of the reaction: p-hydroxybenzoate + solanesyl pyrophosphate = nonaprenyl-4-hydroxybenzoate + diphosphate.


description: Catalysis of the reaction: (2E,6E,10E)-geranylgeranyl diphosphate + sn-glycerol 1-phosphate = diphosphate + sn-3-O-(geranylgeranyl)glycerol 1-phosphate.


description: Catalysis of the reaction: (2E,6E,10E)-geranylgeranyl diphosphate + sn-3-O-(geranylgeranyl)glycerol 1-phosphate = 2,3-bis-O-(geranylgeranyl)-sn-glycerol 1-phosphate + diphosphate.


homospermidine synthase activity

description: Catalysis of the reaction: 2 putrescine = NH3 + sym-homospermidine.


description: Catalysis of the reaction: a 2-oxo acid + L-asparagine = an amino acid + 2-oxosuccinamate.


description: Catalysis of the reaction: (S)-3-amino-2-methylpropanoate + 2-oxoglutarate = 2-methyl-3-oxopropanoate + L-glutamate.


description: Catalysis of the reaction: keto-phenylpyruvate + L-tryptophan = 3-(indol-3-yl)pyruvate + L-phenylalanine.


description: Catalysis of the reaction: pyridoxamine + pyruvate = L-alanine + pyridoxal.


description: Catalysis of the reaction: (S)-3-methyl-2-oxopentanoate + L-valine = 3-methyl-2-oxobutanoate + L-isoleucine.


description: Catalysis of the reaction: 2-oxoglutarate + UDP-2-acetamido-4-amino-2,4,6-trideoxy-D-glucose = L-glutamate + UDP-2-acetamido-4-dehydro-2,6-dideoxy-beta-D-glucose.


description: Catalysis of the reaction: glycine + oxaloacetate = L-aspartate + glyoxylate.


description: Catalysis of the reaction: (2-aminoethyl)phosphonate + pyruvate = L-alanine + phosphonoacetaldehyde.


description: Catalysis of the reaction: (2R)-3-amino-2-methylpropanoate + pyruvate = 2-methyl-3-oxopropanoate + L-alanine.


description: Catalysis of the reaction: D-methionine + pyruvate = 4-methylthio-2-oxobutanoate + L-alanine.


description: Catalysis of the reaction: L-2,4-diaminobutyrate + pyruvate = L-alanine + L-aspartate 4-semialdehyde.


description: Catalysis of the reaction: L-alanine + oxomalonate = aminomalonate + pyruvate.


description: Catalysis of the reaction: 2-oxoglutarate + L-dopa = 3,4-dihydroxyphenylpyruvate + L-glutamate.


description: Catalysis of the reaction: 2,4,6/3,5-pentahydroxycyclohexanone + L-glutamine = 1-amino-1-deoxy-scyllo-inositol + 2-oxoglutaramate.


description: Catalysis of the reaction: 1D-1-guanidino-3-amino-1,3-dideoxy-scyllo-inositol + pyruvate = 1D-1-guanidino-1-deoxy-3-dehydro-scyllo-inositol + L-alanine.


description: Catalysis of the reaction: pyruvate + L-phenylalanine = phenylpyruvate + L-alanine.


description: Catalysis of the reaction: glyoxylate + an aromatic amino acid = L-glycine + an aromatic oxo acid.


description: Catalysis of the reaction: L-kynurenine + glyoxylate = 4-(2-aminophenyl)-2,4-dioxobutanoate + glycine.


description: Catalysis of the reaction: keto-phenylpyruvate + L-glutamine = 2-oxoglutaramate + L-phenylalanine.


description: Catalysis of the reaction: 2-oxoglutarate + 3-amino-6-acetamidohexanoate = L-glutamate + 3-oxo-6-acetamidohexanoate.


description: Catalysis of the reaction: keto-phenylpyruvate + L-aspartate = L-phenylalanine + oxaloacetate.


description: Catalysis of the reaction: 2-oxoglutarate + D-4-hydroxyphenylglycine = 4-hydroxyphenylglyoxylate + L-glutamate.


description: Catalysis of the reaction: microsomal-membrane protein + diphosphate = diphosphate + O-phospho-microsomal-membrane protein.


name: [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity

description: Catalysis of the reaction: [3-hydroxy-3-methylglutaryl-CoA reductase (NADPH)] + ATP = [3-hydroxy-3-methylglutaryl-CoA reductase (NADPH)] phosphate + ADP.


name: [3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] kinase activity

description: Catalysis of the reaction: ATP + 3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring) = ADP + 3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring) phosphate.


description: Catalysis of the reaction: glycerone + phosphoenolpyruvate = glycerone phosphate + pyruvate.


name: inositol tetrakisphosphate 1-kinase activity

description: Catalysis of the reaction: 1D-myo-inositol 3,4,5,6-tetrakisphosphate + ATP = 1D-myo-inositol 1,3,4,5,6-pentakisphosphate + ADP.


name: inositol tetrakisphosphate 5-kinase activity

description: Catalysis of the reaction: 1D-myo-inositol 1,3,4,6-tetrakisphosphate + ATP = 1D-myo-inositol 1,3,4,5,6-pentakisphosphate + ADP.


description: Catalysis of the reaction: sn-glycerol 3-phosphate + D-glucose = D-glucose 6-phosphate + glycerol.


description: Catalysis of the reaction: D-hexose + acyl phosphate = D-hexose phosphate + an acid.


description: Catalysis of the reaction: hexose + phosphoramidate = hexose 1-phosphate + NH3.


description: Catalysis of the reaction: beta-D-glucose + long chain polyphosphate = glucose-6-phosphate + long chain polyphosphate.


description: Catalysis of the reaction: glycerol + diphosphate = glycerol 1-phosphate + H+ + phosphate.


description: Catalysis of the reaction: L-serine + diphosphate = O-phospho-L-serine + H+ + phosphate.


description: Catalysis of the reaction: ATP + dihydrostreptomycin 6-phosphate = ADP + dihydrostreptomycin 3'alpha,6-bisphosphate + 2 H+.


description: Catalysis of the reaction: fructose-6-phosphate + diphosphate = phosphate + fructose-1,6-bisphosphate.


description: Catalysis of the reaction: long-chain-polyphosphate + 3-phospho-D-glyceroyl-phosphate = long-chain-polyphosphate + 3-phosphoglycerate.


description: Catalysis of the reaction: 2'-deoxy-5-methyl-5'-cytidylate + ATP = 5-methyldeoxycytidine diphosphate + ADP + H+.


description: Catalysis of the reaction: dolichyl diphosphate + long-chain-polyphosphate = dolichol-phosphate + long-chain-polyphosphate.


description: Catalysis of the reaction: alpha-D-xylose 1-phosphate + UTP = UDP-D-xylose + diphosphate.


description: Catalysis of the reaction: hexose 1-phosphate + nucleoside triphosphate = NDP-hexose + diphosphate.


description: Catalysis of the reaction: beta-L-fucose 1-phosphate + GTP + H+ = diphosphate + GDP-beta-L-fucose.


description: Catalysis of the reaction: alpha-D-galactose 1-phosphate + dTTP = diphosphate + dTDP-D-galactose.


description: Catalysis of the reaction: alpha-D-glucose 1-phosphate + CTP = CDP-D-glucose + diphosphate.


description: Catalysis of the reaction: alpha-D-glucose 1-phosphate + GTP = diphosphate + GDP-D-glucose.


description: Catalysis of the reaction: D-ribose 5-phosphate + ADP + H+ = ADP-ribose + phosphate.


description: Catalysis of the reaction: aldose 1-phosphate + ADP = phosphate + ADP-aldose.


description: Catalysis of the reaction: aldose 1-phosphate + NDP = phosphate + NDP-aldose.


description: Catalysis of the reaction: sn-glycerol 3-phosphate + CTP = CDP-glycerol + diphosphate.


description: Catalysis of the reaction: D-ribitol 5-phosphate + CTP = CDP-ribitol + diphosphate.


description: Catalysis of the reaction: 1-phospho-alpha-D-glucuronate + UTP = diphosphate + UDP-alpha-D-glucuronate.


GTP guanylyltransferase activity

description: Catalysis of the reaction: 2 GTP + H+ = P(1),P(4)-bis(5'-guanosyl) tetraphosphate + diphosphate + H+.


description: Catalysis of the reaction: 5'-adenylyl sulfate + NH4 = adenosine 5'-phosphoramidate + 2 H+ + sulfate.


description: Catalysis of the reaction: N-methylethanolamine phosphate + CTP = CDP-N-methylethanolamine + diphosphate.


description: Catalysis of the reaction: CDP-choline + sphingosine = CMP + H+ + sphingosyl-phosphocholine.


description: Catalysis of the reaction: glycerophosphate(n) + CDP-glycerol = glycerophosphate(n+1) + CMP.


description: Catalysis of the reaction: ribitol phosphate(n) + CDP-ribitol = ribitol phosphate(n+1) + CMP.


name: UDP-galactose-UDP-N-acetylglucosamine galactose phosphotransferase activity

description: Catalysis of the reaction: UDP-N-acetyl-alpha-D-glucosamine + UDP-D-galactose = H+ + UDP-N-acetyl-6-(D-galactose-1-phospho)-D-glucosamine + UMP.


name: UDP-glucose-glycoprotein glucose phosphotransferase activity

description: Catalysis of the reaction: glycoprotein D-mannose + UDP-D-glucose = glycoprotein 6-(D-glucose-1-phospho)-D-mannose + UMP.


name: 1-alkenyl-2-acylglycerol choline phosphotransferase activity

description: Catalysis of the reaction: 1-alkenyl-2-acylglycerol + CDP-choline = plasmenylcholine + CMP.


name: undecaprenyl-phosphate galactose phosphotransferase activity

description: Catalysis of the reaction: all-trans-undecaprenyl phosphate + UDP-D-galactose = alpha-D-galactosyl-diphosphoundecaprenol + UMP.


description: Catalysis of the reaction: phosphomannan(n) + GDP-mannose = phosphomannan(n+1) + GMP.


description: Catalysis of the reaction: dithioerythritol + thiosulfate = hydrogen sulfide + dithioerythritol disulfide + sulfite.


description: Catalysis of the reaction: alpha-D-glucosyl-1,6-alpha-D-glucosyl-1,6-alpha-D-glucosyl-1,3-1-O-alkyl-2-O-acylglycerol + 3'-phosphoadenosine 5'-phosphosulfate = 6-sulfo-alpha-D-glucosyl-1,6-alpha-D-glucosyl-1,6-alpha-D-glucosyl-1,3-1-O-alkyl-2-O-acylglycerol + adenosine 3',5'-bisphosphate.


description: Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + desulfoglucotropeolin = adenosine 3',5'-diphosphate + glucotropeolin + H+.


description: Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + quercetin 3-sulfate = adenosine 3',5'-diphosphate + H+ + quercetin 3,3'-disulfate.


description: Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + quercetin 3-sulfate = adenosine 3',5'-diphosphate + H+ + quercetin 3,4'-disulfate.


description: Catalysis of the reaction: quercetin 3,3'-bissulfate + 3'-phosphoadenosine 5'-phosphosulfate = quercetin 3,3',7-trissulfate + adenosine 3',5'-bisphosphate.


description: Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + UDP-N-acetyl-D-galactosamine 4-sulfate = adenosine 3',5'-diphosphate + H+ + UDP-N-acetyl-D-galactosamine 4,6-disulfate.


description: Catalysis of the reaction: (S)-3-hydroxy-3-methylglutarate + succinyl-CoA = 3-hydroxy-3-methyl-glutaryl-CoA + succinate.


description: Catalysis of the reaction: S-citramalate + succinyl-CoA = citramalyl-CoA + succinate.


description: Catalysis of the reaction: acetoacetate + butanoyl-CoA = acetoacetyl-CoA + butanoate.


acylglycerol lipase activity

description: Catalysis of the reaction: H2O + acylglycerol = a fatty acid + glycerol.


description: Catalysis of the reaction: 5-(4-acetoxybut-1-ynyl)-2,2'-bithiophene + H2O = 5-(4-hydroxy-but-1-ynyl)-2,2'-bithiophene + acetate + H+.


description: Catalysis of the reaction: 4-methylumbelliferyl acetate + H2O = 4-methylumbelliferone + acetate + H+.


description: Catalysis of the reaction: H2O + N-acetyl-D-galactosaminoglycan = acetate + D-galactosaminoglycan.


name: all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity

description: Catalysis of the reaction: all-trans-retinyl palmitate + H2O = all-trans-retinol + H+ + palmitate.


description: Catalysis of the reaction: 5-(3,4-diacetoxybut-1-ynyl)-2,2'-bithiophene + H2O = 5-(3-hydroxy-4-acetoxybut-1-ynyl)-2,2'-bithiophene + acetate + H+.


description: Catalysis of the reaction: 2-acetyl-1-alkyl-sn-glycerol + H2O = 1-alkyl-sn-glycerol + acetate + H+.


description: Catalysis of the reaction: S-methyl-3-phospho-1-thio-D-glycerate + H2O = S-methyl-1-thio-D-glycerate + phosphate.


description: Catalysis of the reaction: 1-guanidino-1-deoxy-scyllo-inositol 4-phosphate + H2O = 1-guanidino-1-deoxy-scyllo-inositol + phosphate.


name: [hydroxymethylglutaryl-CoA reductase (NADPH)]-phosphatase activity

description: Catalysis of the reaction: H2O + [hydroxymethylglutaryl-CoA reductase (NADPH)] phosphate = phosphate + [hydroxymethylglutaryl-CoA reductase (NADPH)].


name: [3-methyl-2-oxobutanoate dehydrogenase (lipoamide)]-phosphatase activity

description: Catalysis of the reaction: H2O + O-phospho-L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] = L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + phosphate.


description: Catalysis of the reaction: beta-D-fructose 2,6-bisphosphate + H2O = beta-D-fructofuranose 2-phosphate + phosphate.


description: Catalysis of the reaction: H2O + serine phosphoethanolamine = H+ + phosphoethanolamine + serine.


name: [glutamine synthetase]-adenylyl-L-tyrosine phosphorylase activity

description: Catalysis of the reaction: [glutamine synthetase]-O(4)-(5'-adenylyl)-L-tyrosine + phosphate = [glutamine synthetase]-L-tyrosine + ADP.


description: Catalysis of the reaction: H2O + L-1-glycero-3-phosphocholine = glycerol-3-phosphate + choline.


description: Catalysis of the reaction: sn-glycero-3-phosphocholine + H2O = choline phosphate + glycerol + H+.


description: Catalysis of the reaction: H2O + 1-alkyl-sn-glycero-3-phosphoethanolamine = ethanolamine + 1-alkyl-sn-glycerol 3-phosphate.


description: Catalysis of the reaction: H2O + CMP-N-acylneuraminate = N-acylneuraminate + CMP.


description: Catalysis of the reaction: glycerol 1,2-cyclic phosphate + H2O = glycerol 1-phosphate + H+.


description: Catalysis of the reaction: H2O + 1-(sn-glycero-3-phospho)-1D-myoinositol = 1D-myo-inositol 1-phosphate + glycerol.


description: Catalysis of the reaction: 1-(sn-glycero-3-phospho)-1D-myo-inositol + H2O = sn-glycerol 3-phosphate + myo-inositol + H+.


description: Catalysis of the reaction: 6-(alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol = 1,2-diacyl-sn-glycerol + 6-(alpha-D-glucosaminyl)-1D-myo-inositol 1,2-cyclic phosphate.


description: Catalysis of the reaction: dolichyl beta-D-glucosyl phosphate + H2O = dolichol-phosphate + beta-D-glucose.


description: Catalysis of the reaction: dolichyl beta-D-mannosyl phosphate + H2O = dolichol-phosphate + mannose.


description: Catalysis of the reaction: H2O + 6-(D-glucose-1-phospho)-D-mannosylglycoprotein = D-mannosylglycoprotein + D-glucose-alpha-1-phosphate.


phosphonoacetate hydrolase activity

description: Catalysis of the reaction: H2O + phosphonoacetate = acetate + H+ + phosphate.


trithionate hydrolase activity

description: Catalysis of the reaction: H2O + trithionate = H+ + sulfate + thiosulfate.


description: Catalysis of the reaction: H2O + protein alpha-D-glucosyl-1,2-beta-D-galactosyl-L-hydroxylysine = protein beta-D-galactosyl-L-hydroxylysine + beta-D-glucose. The enzyme specifically hydrolyzes glucose from alpha-D-glucosyl- (1->2)-beta-D-galactosyl disaccharide units that are linked to hydroxylysine residues of collagen and collagen-like proteins.


lacto-N-biosidase activity

description: Catalysis of the reaction: H2O + beta-D-Gal-(1,3)-beta-D-GlcNAc-(1,3)-beta-D-Gal-(1,4)-D-Glc = beta-D-Gal-(1,4)-D-Glc + beta-D-Gal-(1,3)-D-GlcNAc.


description: Catalysis of the reaction: H2O + 3-D-glucuronosyl-N2-,6-disulfo-beta-D-glucosamine = glucuronate + N2,6-disulfo-D-glucosamine.


description: Catalysis of the reaction: H2O + a pyrimidine 5'-nucleotide = ribose-5-phosphate + a pyrimidine.


description: Catalysis of the reaction: N(4)-(beta-N-acetyl-D-glucosaminyl)-L-asparagine + H2O = N-acetyl-D-glucosamine + L-asparagine.


name: ADP-ribosyl-[dinitrogen reductase] hydrolase activity

description: Catalysis of the reaction: ADP-ribosyl-[dinitrogen reductase] = adenosine diphosphate ribose + [dinitrogen reductase].


description: Catalysis of the reaction: H2O + 1-(1-alkenyl)-sn-glycero-3-phosphocholine = L-1-glycero-3-phosphocholine + an aldehyde.


description: Catalysis of the reaction: 2 H2O + 2-(acetamidomethylene)succinate = CO2 + NH3 + succinate semialdehyde + acetate.


description: Catalysis of the reaction: H2O + N-(long-chain-acyl)ethanolamine = ethanolamine + a fatty acid.


description: Catalysis of the reaction: N-benzyloxycarbonyl-L-leucine + H2O + H+ = L-leucine + benzyl alcohol + CO2.


description: Catalysis of the reaction: (2Z)-2-(acetamidomethylene)-3-(hydroxymethyl)succinate + 2 H2O + H+ = 2-(hydroxymethyl)-4-oxobutanoate + acetate + CO2 + NH4.


description: Catalysis of the reaction: N(2)-benzoyl-D-arginine-4-nitroanilide + H2O = 4-nitroaniline + N(2)-benzoyl-D-arginine + H+.


arylalkyl acylamidase activity

description: Catalysis of the reaction: H2O + N-acetylarylalkylamine = acetate + arylalkylamine.


name: N-carbamoyl-D-amino acid hydrolase activity

description: Catalysis of the reaction: H2O + N-carbamoyl-D-amino acid = CO2 + NH3 + D-amino acid.


phthalyl amidase activity

description: Catalysis of the reaction: H2O + a phthalylamide = phthalate + substituted amine.


description: Catalysis of the reaction: H2O + N-acetyl-D-galactosamine 6-phosphate = acetate + D-galactosamine 6-phosphate.


N-acyl-D-amino-acid deacylase activity

description: Catalysis of the reaction: H2O + N-acyl-D-amino acid = D-amino acid + an acid.


N-acyl-D-glutamate deacylase activity

description: Catalysis of the reaction: N-acyl-D-glutamate + H2O = D-glutamate + a carboxylate.


N-acyl-D-aspartate deacylase activity

description: Catalysis of the reaction: N-acyl-D-aspartate + H2O = D-aspartate + a carboxylate.


description: Catalysis of the reaction: N-methylhydantoin + ATP + 2 H2O = N-carbamoylsarcosine + ADP + 3 H+ + phosphate.


methylenediurea deaminase activity

description: Catalysis of the reaction: 2 H2O + methylenediurea = CO2 + 2 NH3 + N-hydroxymethylurea.


description: Catalysis of the reaction: 4-hydroxy-1-pyrroline-2-carboxylate + H2O + H+ = 2,5-dioxopentanoate + NH4.


ricinine nitrilase activity

description: Catalysis of the reaction: H2O + ricinine = NH3 + 3-carboxy-4-methoxy-N-methyl-2-pyridone.


cyanoalanine nitrilase activity

description: Catalysis of the reaction: 3-cyano-L-alanine + 2 H2O + H+ = L-aspartate + NH4.


arylacetonitrilase activity

description: Catalysis of the reaction: 2 H2O + 4-chlorophenylacetonitrile = 4-chlorophenylacetate + NH3.


name: nucleoside triphosphate diphosphatase activity

description: Catalysis of the reaction: a nucleoside triphosphate + H2O = a nucleotide + H+ + diphosphate.


description: Catalysis of the reaction: H2O + oligosaccharide-diphosphodolichol = dolichol-phosphate + oligosaccharide phosphate.


description: Catalysis of the reaction: 5-hydroxy-6-methylpyridine-3,4-dicarboxylate + H+ = 5-hydroxy-6-methylpyridine-3-carboxylate + CO2.


name: 2,2-dialkylglycine decarboxylase (pyruvate) activity

description: Catalysis of the reaction: 2,2-dialkylglycine + H+ + pyruvate = L-alanine + CO2 + dialkyl ketone.


description: Catalysis of the reaction: (S)-3-methyl-2-oxopentanoate + H+ = 2-methylbutanal + CO2.


indolepyruvate decarboxylase activity

description: Catalysis of the reaction: indolepyruvate = CO2 + indole acetaldehyde.


description: Catalysis of the reaction: 5-guanidino-2-oxopentanoate + H+ = 4-guanidinobutanal + CO2.


arylmalonate decarboxylase activity

description: Catalysis of the reaction: 2-aryl-2-methylmalonate + H+ = 2-arylpropionate + CO2.


4-oxalocrotonate decarboxylase activity

description: Catalysis of the reaction: 4-oxalocrotonate = CO2 + 2-oxopent-4-enoate.


description: Catalysis of the reaction: 2-dehydro-3-deoxy-L-pentonate = glycolaldehyde + pyruvate.


description: Catalysis of the reaction: 3-deoxy-D-manno-octulosonate = D-arabinose + pyruvate.


description: Catalysis of the reaction: 2-dehydro-3-deoxy-D-arabinonate = glycolaldehyde + pyruvate.


description: Catalysis of the reaction: 6-phospho-5-dehydro-2-deoxy-D-gluconate = 3-oxopropanoate + glycerone phosphate.


description: Catalysis of the reaction: 4-hydroxy-4-methyl-2-oxoglutarate = 2 pyruvate.


description: Catalysis of the reaction: H2O + phosphoenolpyruvate + N-acyl-D-mannosamine 6-phosphate = phosphate + N-acylneuraminate 9-phosphate.


description: Catalysis of the reaction: 3-hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA + 4 H+ = 7-methyl-3-oxooct-6-enoyl-CoA + acetate.


description: Catalysis of the reaction: (1-hydroxycyclohexan-1-yl)acetyl-CoA = acetyl-CoA + cyclohexanone.


description: Catalysis of the reaction: erythro-3-hydroxy-L-aspartate = NH3 + oxaloacetic acid.


description: Catalysis of the reaction: 5-dehydro-4-deoxy-D-glucarate + H+ = 2,5-dioxopentanoate + CO2 + H2O.


description: Catalysis of the reaction: 2-dehydro-3-deoxy-L-arabinonate = 2,5-dioxopentanoate + H2O.


description: Catalysis of the reaction: (3R)-hydroxybutanoyl-[acyl-carrier-protein] = (2E)-butenoyl-[acyl-carrier-protein] + H2O.


description: Catalysis of the reaction: (3R)-3-hydroxyoctanoyl-[acyl-carrier protein] = H2O + (2E)-octenoyl-[acyl-carrier protein].


name: protoaphin-aglucone dehydratase (cyclizing) activity

description: Catalysis of the reaction: protoaphin aglucone = H2O + xanthoaphin.


name: ATP-dependent NAD(P)H-hydrate dehydratase activity

description: Catalysis of the reaction: (6S)-6beta-hydroxy-1,4,5,6-tetrahydronicotinamide adenine dinucleotide + ATP = ADP + 3 H+ + NADH + phosphate.


phaseollidin hydratase activity

description: Catalysis of the reaction: phaseollidin hydrate = H2O + phaseollidin.


description: Catalysis of the reaction: 16-alpha-hydroxyprogesterone = H2O + 16-dehydroprogesterone.


2-methylisocitrate dehydratase activity

description: Catalysis of the reaction: (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate = cis-2-methylaconitate + H2O.


exo-(1,4)-alpha-D-glucan lyase activity

description: Catalysis of the reaction: linear alpha-D-glucan = 1,5-anhydro-D-fructose + beta-D-glucose.


beta-pyrazolylalanine synthase activity

description: Catalysis of the reaction: O-acetyl-L-serine + pyrazole = 3-(pyrazol-1-yl)-L-alanine + acetate + H+.


description: Catalysis of the reaction: (S)-3-aminobutanoyl-CoA = crotonoyl-CoA + NH4.


description: Catalysis of the reaction: L-2-amino-4-chloropent-4-enoate + H2O = 2-oxopent-4-enoate + chloride + H+ + NH4.


(+)-delta-cadinene synthase activity

description: Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = diphosphate + (+)-delta-cadinene.


name: phenylalanine racemase (ATP-hydrolyzing) activity

description: Catalysis of the reaction: L-phenylalanine + ATP + H2O = D-phenylalanine + AMP + diphosphate + 2 H+.


description: Catalysis of the reaction: L-2-aminohexano-6-lactam = D-2-aminohexano-6-lactam.


description: Catalysis of the reaction: heparosan-N-sulfate D-glucuronate = heparosan-N-sulfate L-iduronate.


description: Catalysis of the reaction: N-acyl-D-glucosamine 6-phosphate = N-acyl-D-mannosamine 6-phosphate.


description: Catalysis of the reaction: cis-2-chloro-4-carboxymethylenebut-2-en-1,4-olide = trans-2-chloro-4-carboxymethylenebut-2-en-1,4-olide.


description: Catalysis of the reaction: glucose-1-phosphate = glucose-6-phosphate; using D-glucose as a cofactor.


description: Catalysis of the reaction: 4-carboxymethyl-4-methylbut-2-en-1,4-olide = 4-carboxymethyl-3-methylbut-2-en-1,4-olide.


description: Catalysis of the reaction: 4-[(1->4)-alpha-D-glucosyl](n-1)-D-glucose = 1-alpha-D-[(1->4)-alpha-D-glucosyl](n-1)-alpha-D-glucopyranoside.


description: Catalysis of the reaction: maltose = trehalose.


description: Catalysis of the reaction: 2-(carboxymethyl)-5-oxo-2,5-dihydro-2-furoate = 3-carboxy-cis,cis-muconate + H+.


name: D-alanine [D-alanyl carrier protein] ligase activity

description: Catalysis of the ATP-dependent activation of D-alanine and its transfer as a thiol ester to the phosphopantheinyl prosthetic group of a D-alanyl carrier protein, according to the reaction: ATP + D-alanine + a [D-alaninyl carrier protein] = a D-alanyl-[D-alanyl carrier protein] + AMP + diphosphate.


name: long-chain fatty acid--protein ligase activity

description: Catalysis of the reaction: a long-chain fatty acid + ATP + L-cysteinyl-[protein] = AMP + diphosphate + S-(long-chain fatty acyl)-L-cysteinyl-[protein]. A long-chain fatty acid has an aliphatic tail containing 13 to 22 carbons.


phenylacetate-CoA ligase activity

description: Catalysis of the reaction: ATP + CoA + phenylacetate = AMP + diphosphate + H+ + phenylacetyl-CoA.


description: Catalysis of the reaction: CoA + 3-alpha,7-alpha-dihydroxy-5-beta-cholestanate + ATP = 3-alpha,7-alpha-dihydroxy-5-beta-cholestanoyl-CoA + diphosphate + AMP.


name: aspartate-ammonia ligase (ADP-forming) activity

description: Catalysis of the reaction: L-aspartate + ATP + NH4 = L-asparagine + ADP + 2 H+ + phosphate.


trypanothione synthase activity

description: Catalysis of the reaction: reduced glutathione + glutathionylspermidine + ATP = trypanothione + ADP + phosphate.


description: Catalysis of the reaction: UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysine + ATP + D-alanyl-D-alanine = phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine + ADP.


description: Catalysis of the reaction: alanyl-poly(glycerolphosphate) + D-alanine + ATP = D-alanyl-alanyl-poly(glycerolphosphate) + phosphate + ADP.


description: Catalysis of the reaction: L-lysine + ATP + UDP-N-acetylmuramoyl-L-alanyl-D-glutamate = ADP + 2 H+ + phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysine.


description: Catalysis of the reaction: 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H2O + imidazol-4-ylacetate = 1-(5-phosphoribosyl)imidazol-4-ylacetate + ADP + diphosphate + 2 H+ + phosphate.


name: regulation of response to osmotic stress

category: biolink:BiologicalProcess biolink:Occurrent biolink:OntologyClass biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: Any process that modulates the rate or extent of the response to osmotic stress.


oligogalacturonide lyase activity

description: Catalysis of the reaction: 4-(4-deoxy-alpha-D-gluc-4-enuronosyl)-D-galacturonate = 2 5-dehydro-4-deoxy-D-glucuronate.


heparin lyase activity

description: Catalysis of the eliminative cleavage of polysaccharides containing 1,4-linked D-glucuronate or L-iduronate residues and 1,4-alpha-linked 2-sulfoamino-2-deoxy-6-sulfo-D-glucose residues to give oligosaccharides with terminal 4-deoxy-alpha-D-gluc-4-enuronosyl groups at their nonreducing ends.


pectate disaccharide-lyase activity

description: Catalysis of the reaction: a pectate = a pectate + 4-(4-deoxy-alpha-D-galact-4-enuronosyl)-D-galacturonate. This reaction is the eliminative cleavage of 4-(4-deoxy-alpha-D-galact-4-enuronosyl)-D-galacturonate from the reducing end of pectate, i.e. de-esterified pectin.


pectin lyase activity

description: Catalysis of the reaction: a pectin = an oligosaccharide with 4-deoxy-6-O-methyl-alpha-D-galact-4-enuronate end + a pectin. This reaction is the eliminative cleavage of (1->4)-alpha-D-galacturonan methyl ester to give oligosaccharides with 4-deoxy-6-O-methyl-alpha-D-galact-4-enuronosyl groups at their nonreducing ends.


poly(alpha-L-guluronate) lyase activity

description: Catalysis of the reaction: polysaccharides containing a terminal alpha-L-guluronate group = oligosaccharides with 4-deoxy-alpha-L-erythro-hex-4-enuronosyl end. This reaction is the eliminative cleavage of polysaccharides containing a terminal a-L-guluronate group, to give oligopolysaccharides with 4-deoxy-a-L-erythro-hex-4-enuronosyl groups at their nonreducing ends.


xanthan lyase activity

description: Catalysis of the reaction: xanthan = oligosaccharide with 4-deoxy-alpha-L-threo-hex-4-enuronosyl end + pyruvylate mannose. This reaction is the eliminative cleavage of the terminal beta-D-mannosyl-beta-D-1,4-glucuronosyl linkage of the side-chain of the polysaccharide xanthan, leaving a 4-deoxy-alpha-L-threo-hex-4-enuronosyl group at the terminus of the side-chain.


description: Catalysis of the reaction: CDP-choline + ceramide = CMP + H+ + sphingomyelin.


description: Catalysis of the reaction: L-serine + CDP-ethanolamine = L-serine-phosphoethanolamine + CMP + H+.


description: Catalysis of the transfer of a glycerophospho group from one membrane-derived oligosaccharide to another.


vesicle transport along microtubule

description: The directed movement of a vesicle along a microtubule, mediated by motor proteins. This process begins with the attachment of a vesicle to a microtubule, and ends when the vesicle reaches its final destination.


name: mitochondrion transport along microtubule

description: The directed movement of a mitochondrion along a microtubule, mediated by motor proteins.


name: calcium-dependent phospholipase A2 activity

description: Catalysis of the reaction: phosphatidylcholine + H2O = 1-acylglycerophosphocholine + a carboxylate. This reaction requires Ca2+.


name: calcium-independent phospholipase A2 activity

description: Catalysis of the reaction: phosphatidylcholine + H2O = 1-acylglycerophosphocholine + a carboxylate. This reaction does not require Ca2+.


(+)-borneol dehydrogenase activity

description: Catalysis of the reaction: (+)-borneol + NAD+ = (1R, 4R)-camphor + H+ + NADH.


(+)-neomenthol dehydrogenase activity

description: Catalysis of the reaction: (+)-neomenthol + NADP+ = (2S,5R)-menthone + H+ + NADPH.


(+)-sabinol dehydrogenase activity

description: Catalysis of the reaction: (+)-cis-sabinol + NAD+ = (1S,5S)-sabinone + H+ + NADH.


(-)-borneol dehydrogenase activity

description: Catalysis of the reaction: (-)-borneol + NAD+ = (1S,4S)-camphor + H+ + NADH.


(-)-menthol dehydrogenase activity

description: Catalysis of the reaction: (-)-menthol + NADP+ = (2S,5R)-menthone + H+ + NADPH.


(-)-menthol monooxygenase activity

description: Catalysis of the reaction: (-)-menthol + H+ + NADPH + O2 = 1,4-menthane-3,8-diol + H2O + NADP+.


(deoxy)adenylate kinase activity

description: Catalysis of the reaction: ATP + dAMP = ADP + dADP.


description: Catalysis of the reaction: ATP + deoxynucleoside phosphate = ADP + deoxynucleoside diphosphate.


(R)-2-methylmalate dehydratase activity

description: Catalysis of the reaction: (R)-citramalate = 2-methylmaleate + H2O.


description: Catalysis of the reaction: (R)-4-dehydropantoate + H2O + NAD+ = (R)-3,3-dimethylmalate + 2 H+ + NADH.


(S)-2-methylmalate dehydratase activity

description: Catalysis of the reaction: S-citramalate = H2O + mesaconate.


description: Catalysis of the reaction: (S)-methylmalonyl-CoA + H2O = CoA + H+ + methylmalonate.


(S,S)-butanediol dehydrogenase activity

description: Catalysis of the reaction: (S,S)-butane-2,3-diol + NAD+ = acetoin + H+ + NADH.


1,2-alpha-L-fucosidase activity

description: Catalysis of the reaction: H2O + methyl-2-alpha-L-fucopyranosyl-beta-D-galactoside = L-fucose + methyl beta-D-galactoside.


description: Catalysis of the reaction: [(1->3)-beta-D-glucosyl](n) + phosphate = [(1->3)-beta-D-glucosyl](n-1) + alpha-D-glucose 1-phosphate; substrates include laminarin.


description: Catalysis of the reaction: [oligomeric (1->3)-beta-D-glucosyl](n) + phosphate = [(1->3)-beta-D-glucosyl](n-1) + alpha-D-glucose 1-phosphate.


1,3-propanediol dehydrogenase activity

description: Catalysis of the reaction: propane-1,3-diol + NAD+ = 3-hydroxypropanal + NADH + H+.


1,4-beta-D-xylan synthase activity

description: Catalysis of the reaction: UDP-D-xylose + [(1->4)-beta-D-xylan](n) = UDP + [(1->4)-beta-D-xylan](n+1).


1-methyladenosine nucleosidase activity

description: Catalysis of the reaction: 1-methyladenosine + H2O = 1-methyladenine + ribofuranose.


name: quinate dehydrogenase (quinone) activity

description: Catalysis of the reaction: (-)-quinate + pyrroloquinoline-quinone = (-)-3-dehydroquinate + pyrroloquinoline-quinol.


description: Catalysis of the reaction: 11-cis-retinyl palmitate + H2O = 11-cis-retinol + H+ + palmitate.


description: Catalysis of the reaction: 3alpha,7alpha,12beta-trihydroxy-5beta-cholanate + NADP+ = 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanate + H+ + NADPH.


15-oxoprostaglandin 13-oxidase activity

description: Catalysis of the reaction: (5Z)-(15S)-11-alpha-hydroxy-9,15-dioxoprostanoate + NAD(P)+ -> (5Z)-(15S)-11-alpha-hydroxy-9,15-dioxoprosta-13-enoate + NAD(P)H + H+.


16-hydroxysteroid epimerase activity

description: Catalysis of the reaction: 16-alpha-hydroxysteroid = 16-beta-hydroxysteroid.


2'-hydroxydaidzein reductase activity

description: Catalysis of the reaction: 2'-hydroxydihydrodaidzein + NADP+ = 2'-hydroxydaidzein + NADPH + H+.


2'-hydroxyisoflavone reductase activity

description: Catalysis of the reaction: vestitone + NADP+ = 2'-hydroxyformononetin + NADPH + H+.


description: Catalysis of the reaction: ATP + 2,3-dihydroxybenzoate + L-serine = products of ATP breakdown + N-(2,3-dihydroxybenzoyl)-L-serine.


description: Catalysis of the reaction: 2,3-dihydroxyindole + O2 = anthranilate + CO2 + H+.


2,3-dimethylmalate lyase activity

description: Catalysis of the reaction: (2R,3S)-2,3-dimethylmalate = propanoate + pyruvate.


description: Catalysis of the reaction: 2,4-diaminopentanoate + H2O + NAD(P)+ = 2-amino-4-oxopentanoate + NH3 + NAD(P)H + H+.


2,5-dioxopiperazine hydrolase activity

description: Catalysis of the reaction: 2,5-dioxopiperazine + H2O = glycylglycine.


name: 2,5-dioxovalerate dehydrogenase (NADP+) activity

description: Catalysis of the reaction: 2,5-dioxopentanoate + NADP+ + H2O = 2-oxoglutarate + NADPH + H+.


2-acetolactate mutase activity

description: Catalysis of the reaction: 2-acetolactate = 3-hydroxy-3-methyl-2-oxobutanoate.


2-alkyn-1-ol dehydrogenase activity

description: Catalysis of the reaction: 2-butyne-1,4-diol + NAD+ = 4-hydroxy-2-butynal + H+ + NADH.


2-aminoadipate transaminase activity

description: Catalysis of the reaction: 2-oxoglutarate + L-2-aminoadipate = 2-oxoadipate + L-glutamate.


2-aminohexanoate transaminase activity

description: Catalysis of the reaction: L-2-aminohexanoate + 2-oxoglutarate = 2-oxohexanoate + L-glutamate.


description: Catalysis of the reaction: 2-carboxy-D-arabinitol 1-phosphate + H2O = 2-carboxy-D-arabinitol + phosphate.


2-deoxyglucosidase activity

description: Catalysis of the reaction: H2O + a 2-deoxy-alpha-D-glucoside = 2-deoxy-D-glucose + an alcohol.


2-enoate reductase activity

description: Catalysis of the reaction: butanoate + NAD+ = 2-butenoate + NADH + H+.


2-furoate-CoA ligase activity

description: Catalysis of the reaction: 2-furoate + ATP + CoA = 2-furoyl-CoA + AMP + diphosphate + H+.


2-furoyl-CoA dehydrogenase activity

description: Catalysis of the reaction: 2-furoyl-CoA + A + H2O = 5-hydroxy-2-furoyl-CoA + AH(2) + H+.


2-hexadecenal reductase activity

description: Catalysis of the reaction: NADP+ + palmitaldehyde = trans-hexadec-2-enal + H+ + NADPH.


description: Catalysis of the reaction: biphenyl-2-ol + H+ + NADH + O2 = biphenyl-2,3-diol + H2O + NAD+.


description: Catalysis of the reaction: (S)-2-hydroxyglutarate + acceptor = 2-oxoglutarate + reduced acceptor.


description: Catalysis of the reaction: 2-hydroxypyridine + AH(2) + O2 = 2,5-dihydroxypyridine + A + H2O.


2-methylcitrate dehydratase activity

description: Catalysis of the reaction: (2S,3S)-2-methylcitrate = cis-2-methylaconitate + H2O.


2-methyleneglutarate mutase activity

description: Catalysis of the reaction: 2-methyleneglutarate = 2-methylene-3-methylsuccinate.


2-nitrophenol 2-monooxygenase activity

description: Catalysis of the reaction: 2-nitrophenol + 2 H+ + 2 NADPH + O2 = catechol + H2O + 2 NADP+ + nitrite.


2-oxoadipate reductase activity

description: Catalysis of the reaction: 2-hydroxyadipate + NAD+ = 2-oxoadipate + H+ + NADH.


name: 2-oxoaldehyde dehydrogenase (NAD+) activity

description: Catalysis of the reaction: a 2-oxoaldehyde + NAD+ + H2O = a 2-oxo acid + NADH + H+.


name: 2-oxoaldehyde dehydrogenase (NADP+) activity

description: Catalysis of the reaction: a 2-oxoaldehyde + NADP+ + H2O = a 2-oxo acid + NADPH + H+.


2-oxoglutarate synthase activity

description: Catalysis of the reaction: 2-oxoglutarate + CoA + oxidized ferredoxin = succinyl-CoA + CO2 + reduced ferredoxin.


description: Catalysis of the reaction: 2-oxo-2H-pyran-4,6-dicarboxylate + H2O = 4-carboxy-2-hydroxyhexa-2,4-dienedioate + H+.


description: Catalysis of the reaction: 3',5'-cyclic GMP + H2O = GMP + H+.


description: Catalysis of the reaction: 3,4-dihydroxyphthalate + H+ = 3,4-dihydroxybenzoate + CO2.


3-aci-nitropropanoate oxidase activity

description: Catalysis of the reaction: 3-aci-nitropropanoate + H2O + O2 = 3-oxopropanoate + H2O2 + nitrite.


3-cyanoalanine hydratase activity

description: Catalysis of the reaction: L-asparagine = 3-cyano-L-alanine + H2O + H+.


description: Catalysis of the reaction: 3-dehydro-L-gulonate + NAD(P)+ = (4R,5S)-4,5,6-trihydroxy-2,3-dioxohexanoate + NAD(P)H + H+.


3-dehydrosphinganine reductase activity

description: Catalysis of the reaction: NADP+ + sphinganine = 3-dehydrosphinganine + H+ + NADPH.


3-hydroxyanthranilate oxidase activity

description: Catalysis of the reaction: 3-hydroxyanthranilate + O2 = 6-imino-5-oxocyclohexa-1,3-dienecarboxylate + H2O2.


3-hydroxyaspartate aldolase activity

description: Catalysis of the reaction: (3R)-3-hydroxy-L-aspartate = glycine + glyoxylate.


description: Catalysis of the reaction: 3-hydroxybenzoate + AH(2) + O2 = 2,3-dihydroxybenzoate + A + H2O.


description: Catalysis of the reaction: 3-hydroxycyclohexanone + A = AH(2) + cyclohexane-1,3-dione.


name: 3-hydroxypropionate dehydrogenase (NAD+) activity

description: Catalysis of the reaction: 3-hydroxypropanoate + NAD+ = 3-oxopropanoate + H+ + NADH.


3-ketovalidoxylamine C-N-lyase activity

description: Catalysis of the reaction: 4-nitrophenyl-3-ketovalidamine = 4-nitroaniline + 5-D-(5/6)-5-C-(hydroxymethyl)-2,6-dihydroxycyclohex-2-en-1-one + H+.


3-methyleneoxindole reductase activity

description: Catalysis of the reaction: 3-methyloxindole + NADP+ = 3-methyleneoxindole + H+ + NADPH.


description: Catalysis of the reaction: a 3-oxo-5-beta-steroid + acceptor = a 3-oxo-D4-steroid + reduced acceptor.


3-oxoadipate CoA-transferase activity

description: Catalysis of the reaction: succinyl-CoA + 3-oxoadipate = succinate + 3-oxoadipyl-CoA.


3-oxoadipate enol-lactonase activity

description: Catalysis of the reaction: 3-oxoadipate enol-lactone + H2O = 3-oxoadipate.


3-oxosteroid 1-dehydrogenase activity

description: Catalysis of the reaction: a 3-oxosteroid + acceptor = a 3-oxo-D1-steroid + reduced acceptor.


3-phosphoglycerate phosphatase activity

description: Catalysis of the reaction: 3-phospho-D-glycerate + H2O = D-glycerate + phosphate.


description: Catalysis of the reaction: 4-acetamidobutanoate + H2O = acetate + 4-aminobutanoate.


description: Catalysis of the reaction: 4-acetamidobutanoyl-CoA + H2O = 4-aminobutanoyl-CoA + acetate.


description: Catalysis of the reaction: (R)-2-(carboxymethyl)-5-oxo-2,5-dihydro-2-furoate + H+ = 5-oxo-4,5-dihydro-2-furylacetate + CO2.


4-chlorobenzoate dehalogenase activity

description: Catalysis of the reaction: 4-chlorobenzoate + H2O = 4-hydroxybenzoate + chloride + H+.


description: Catalysis of the reaction: 4-hydroxybutanoate + NAD+ = H+ + NADH + succinate semialdehyde.


description: Catalysis of the reaction: 4-hydroxy-L-glutamate + 2-oxoglutarate = 4-hydroxy-2-oxoglutarate + L-glutamate.


4-hydroxymandelate oxidase activity

description: Catalysis of the reaction: (S)-4-hydroxymandelate + H+ + O2 = 4-hydroxybenzaldehyde + CO2 + H2O2.


4-hydroxyproline epimerase activity

description: Catalysis of the reaction: trans-4-hydroxy-L-proline = cis-4-hydroxy-D-proline.


description: Catalysis of the reaction: 4-methylene-L-glutamate + ATP + NH4 = 4-methylene-L-glutamine + AMP + diphosphate + 2 H+.


4-methyleneglutaminase activity

description: Catalysis of the reaction: 4-methylene-L-glutamine + H2O = 4-methylene-L-glutamate + NH4.


4-methyloxaloacetate esterase activity

description: Catalysis of the reaction: 4-methoxy-2,4-dioxobutanoate + H2O = H+ + methanol + oxaloacetate.


4-oxalmesaconate hydratase activity

description: Catalysis of the reaction: 2-hydroxy-4-oxobutane-1,2,4-tricarboxylate = (1E)-4-oxobut-1-ene-1,2,4-tricarboxylate + H2O.


4-pyridoxolactonase activity

description: Catalysis of the reaction: 4-pyridoxolactone + H2O = 4-pyridoxate + H+.


description: Catalysis of the reaction: 5'-acylphosphoadenosine + H2O = AMP + a carboxylate.


description: Catalysis of the reaction: 5alpha-ergosta-7,22-diene-3beta,5-diol = ergosterol + H2O.


5-aminopentanamidase activity

description: Catalysis of the reaction: 5-aminopentanamide + H2O = 5-aminopentanoate + NH3.


5-aminovalerate transaminase activity

description: Catalysis of the reaction: 2-oxoglutarate + 5-aminopentanoate = 5-oxopentanoate + L-glutamate.


5-dehydro-2-deoxygluconokinase activity

description: Catalysis of the reaction: ATP + 5-dehydro-2-deoxy-D-gluconate = ADP + 6-phospho-5-dehydro-2-deoxy-D-gluconate.


description: Catalysis of the reaction: 5-hydroxypentanoate + acetyl-CoA = 5-hydroxy-pentanoyl-CoA + acetate.


5-pyridoxate dioxygenase activity

description: Catalysis of the reaction: 5-pyridoxate + NADPH + O2 = 2-(acetamidomethylene)-3-(hydroxymethyl)succinate) + NADP+.


6-acetylglucose deacetylase activity

description: Catalysis of the reaction: 6-acetyl-D-glucose + H2O = D-glucose + acetate + H+.


description: Catalysis of the reaction: (6S)-6-hydroxyhyoscyamine + 2-oxoglutarate + O2 = CO2 + H2O + H+ + scopolamine + succinate.


6-hydroxynicotinate reductase activity

description: Catalysis of the reaction: 1,4,5,6-tetrahydro-6-oxonicotinate + oxidized ferredoxin = 6-hydroxynicotinate + reduced ferredoxin.


description: Catalysis of the reaction: 6-methylsalicylate + H+ = 3-cresol + CO2.


6-oxocineole dehydrogenase activity

description: Catalysis of the reaction: 6-oxocineole + H+ + NADPH + O2 = 1,6,6-trimethyl-2,7-dioxabicyclo[3.2.2]nonan-3-one + H2O + NADP+.


7-dehydrocholesterol reductase activity

description: Catalysis of the reaction: cholesterol + NADP+ = 7-dehydrocholesterol + H+ + NADPH.


8-oxocoformycin reductase activity

description: Catalysis of the reaction: coformycin + NADP+ = 8-oxocoformycin + 2 H+ + NADPH.


abequosyltransferase activity

description: Catalysis of the reaction: CDP-abequose + D-mannosyl-L-rhamnosyl-D-galactose-1-diphospholipid = CDP + D-abequosyl-D-mannosyl-rhamnosyl-D-galactose-1-diphospholipid.


acetate kinase (diphosphate) activity

description: Catalysis of the reaction: acetate + diphosphate = acetyl phosphate + phosphate.


acetoacetate decarboxylase activity

description: Catalysis of the reaction: acetoacetate + H+ = acetone + CO2.


acetoacetyl-CoA hydrolase activity

description: Catalysis of the reaction: acetoacetyl-CoA + H2O = acetoacetate + CoA + H+.


acetoin racemase activity

description: Catalysis of the reaction: (S)-acetoin = (R)-acetoin.


acetolactate decarboxylase activity

description: Catalysis of the reaction: (S)-2-hydroxy-2-methyl-3-oxobutanoate = (R)-2-acetoin + CO2.


hydroxynitrilase activity

description: Catalysis of the reaction: a hydroxynitrile = cyanide + an aldehyde or ketone.


acetylindoxyl oxidase activity

description: Catalysis of the reaction: N-acetylindoxyl + O2 = N-acetylisatin + unknown.


acetylputrescine deacetylase activity

description: Catalysis of the reaction: N-acetylputrescine + H2O = acetate + putrescine.


acetylsalicylate deacetylase activity

description: Catalysis of the reaction: acetylsalicylate + H2O = acetate + H+ + salicylate.


acetylspermidine deacetylase activity

description: Catalysis of the reaction: N(8)-acetylspermidine + H2O = acetate + spermidine.


acid-CoA ligase (GDP-forming) activity

description: Catalysis of the reaction: a carboxylate + CoA + GTP = acyl-CoA + GDP + H+ + phosphate.


aconitate decarboxylase activity

description: Catalysis of the reaction: cis-aconitate + H+ = CO2 + itaconate.


aconitate delta-isomerase activity

description: Catalysis of the reaction: trans-aconitate = cis-aconitate.


actinomycin lactonase activity

description: Catalysis of the reaction: actinomycin + H2O = actinomycinic monolactone.


acyl-CoA dehydrogenase (NADP+) activity

description: Catalysis of the reaction: acyl-CoA + NADP+ = 2,3-dehydroacyl-CoA + NADPH + H+.


fatty acyl-CoA hydrolase activity

description: Catalysis of the reaction: a fatty acyl-CoA + H2O = a fatty acid + CoA + H+.


acylagmatine amidase activity

description: Catalysis of the reaction: N(4)-benzoylagmatine + H2O = agmatine + benzoate.


acylcarnitine hydrolase activity

description: Catalysis of the reaction: O-acylcarnitine + H2O = a fatty acid + L-carnitine.


acylglycerol kinase activity

description: Catalysis of the reaction: ATP + acylglycerol = ADP + acyl-sn-glycerol 3-phosphate.


acylpyruvate hydrolase activity

description: Catalysis of the reaction: a 3-acylpyruvate + H2O = a carboxylate + pyruvate.


adenosine nucleosidase activity

description: Catalysis of the reaction: adenosine + H2O = D-ribose + adenine.


adenosine-phosphate deaminase activity

description: Catalysis of the reaction: an adenosine-phosphate + H20 = an inosine phosphate + NH3. Catalyzes the deamination of AMP, ADP or ATP.


adenosine-tetraphosphatase activity

description: Catalysis of the reaction: adenosine 5'-tetraphosphate + H2O = ATP + phosphate.


S-adenosyl-L-methionine lyase activity

description: Catalysis of the reaction: S-adenosyl-L-methionine = L-homoserine lactone + S-methyl-5'-thioadenosine.


adenylylsulfatase activity

description: Catalysis of the reaction: 5'-adenylyl sulfate + H2O = AMP + 2 H+ + sulfate.


ADP-thymidine kinase activity

description: Catalysis of the reaction: ADP + thymidine = AMP + thymidine 5'-phosphate.


ADP deaminase activity

description: Catalysis of the reaction: ADP + H2O = IDP + NH3.


description: Catalysis of the reaction: 3-ADP-2-phosphoglycerate + H2O = 3-ADP-glycerate + phosphate.


ADP-ribose diphosphatase activity

description: Catalysis of the reaction: ADP-ribose + H2O = AMP + D-ribose 5-phosphate.


agmatine deiminase activity

description: Catalysis of the reaction: agmatine + H2O = N-carbamoylputrescine + NH3.


agmatine kinase activity

description: Catalysis of the reaction: agmatine + ATP = N(4)-phosphoagmatine + ADP + 3 H+.


description: Catalysis of the reaction: 4-coumaroyl-CoA + agmatine = N-(4-guanidiniumylbutyl)-4-hydroxycinnamamide + CoA + H+.


alanine-oxo-acid transaminase activity

description: Catalysis of the reaction: L-alanine + a 2-oxo acid = pyruvate + an L-amino acid.


alanopine dehydrogenase activity

description: Catalysis of the reaction: 2,2'-iminodipropanoate + H2O + NAD+ = L-alanine + H+ + NADH + pyruvate.


description: Catalysis of the reaction: 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + L-alanyl-tRNA(Ala) = 1,2-diacyl-sn-glycero-3-phospho-1'-(3'-O-L-alanyl)-sn-glycerol + tRNA(Ala).


albendazole monooxygenase activity

description: Catalysis of the reaction: albendazole + H+ + NADPH + O2 = albendazole S-oxide + H2O + NADP+.


alcohol oxidase activity

description: Catalysis of the reaction: a primary alcohol + O2 = an aldehyde + H2O2.


aldose 1-dehydrogenase activity

description: Catalysis of the reaction: D-aldose + NAD+ = D-aldonolactone + NADH.


name: aldose-6-phosphate reductase (NADPH) activity

description: Catalysis of the reaction: D-glucitol 6-phosphate + NADP+ = D-glucose 6-phosphate + H+ + NADPH.


description: Catalysis of the reaction: alpha-D-aldosyl1 beta-D-fructoside + D-aldose2 = D-aldose1 + alpha-D-aldosyl2 beta-D-fructoside.


alginate synthase activity

description: Catalysis of the reaction: GDP-D-mannuronate + alginate(n) = GDP + alginate(n+1).


description: Catalysis of the reaction: alizarin + UDP-D-glucose = 1-hydroxy-2-(beta-D-glucosyloxy)-9,10-anthraquinone + H+ + UDP.


name: alkan-1-ol dehydrogenase (acceptor) activity

description: Catalysis of the reaction: primary alcohol + acceptor = aldehyde + reduced acceptor.


name: alkanal monooxygenase (FMN-linked) activity

description: Catalysis of the reaction: R-CHO + reduced FMN + O2 = R-COOH + FMN + H2O + light.


alkylacetylglycerophosphatase activity

description: Catalysis of the reaction: 1-alkyl-2-acetyl-sn-glycerol 3-phosphate + H2O = 2-acetyl-1-alkyl-sn-glycerol + phosphate.


alkylamidase activity

description: Catalysis of the reaction: N-methylhexanamide + H2O = hexanoate + methylammonium.


alkylglycerol kinase activity

description: Catalysis of the reaction: 1-alkyl-sn-glycerol + ATP = 1-alkyl-sn-glycerol 3-phosphate + ADP + 2 H+.


alkylglycerone kinase activity

description: Catalysis of the reaction: O-alkylglycerone + ATP = O-alkylglycerone phosphate + ADP + 2 H+.


alkylhalidase activity

description: Catalysis of the reaction: bromochloromethane + H2O = bromide + chloride + formaldehyde + 2 H+.


allantoate deiminase activity

description: Catalysis of the reaction: allantoate + H2O + H+ = CO2 + NH3 + ureidoglycine.


allantoin racemase activity

description: Catalysis of the reaction: (S)-(+)-allantoin = (R)-(-)-allantoin.


alliin lyase activity

description: Catalysis of the reaction: an S-alkyl-L-cysteine S-oxide = an alkyl sulfenate + 2-aminoacrylate.


allyl-alcohol dehydrogenase activity

description: Catalysis of the reaction: allyl alcohol + NADP+ = acrolein + H+ + NADPH.


description: Catalysis of the reaction: alpha,alpha-trehalose + phosphate = D-glucose + beta-D-glucose 1-phosphate.


alpha-1,3-glucan synthase activity

description: Catalysis of the reaction: UDP-glucose + [alpha-D-glucosyl-(1,3)]n = UDP + [alpha-D-glucosyl-(1,3)]n+1.


alpha-amino-acid esterase activity

description: Catalysis of the reaction: an alpha-amino acid ester + H2O = an alpha-amino acid + an alcohol.


alpha-santonin 1,2-reductase activity

description: Catalysis of the reaction: 1,2-dihydrosantonin + NAD(P)+ = alpha-santonin + NAD(P)H + H+.


amidinoaspartase activity

description: Catalysis of the reaction: N-amidino-L-aspartate + H2O = L-aspartate + urea.


amino-acid racemase activity

description: Catalysis of the reaction: an L-amino acid = a D-amino acid.


aminobenzoate decarboxylase activity

description: Catalysis of the reaction: 4(or 2)-aminobenzoate = aniline + CO2.


description: Catalysis of the reaction: acetyl-CoA + kanamycin B = N(6')-acetylkanamycin B + CoA + H+. This is acetylation of the 6'-amino group of the 6-deoxy-6-aminoglucose ring.


aminoimidazolase activity

description: Catalysis of the reaction:4-aminoimidazole + H20 = imidazol-4-one + NH3.


aminolevulinate transaminase activity

description: Catalysis of the reaction: 5-aminolevulinate + pyruvate = 4,5-dioxopentanoate + L-alanine.


ammonia kinase activity

description: Catalysis of the reaction: ATP + NH4 = ADP + 3 H+ + phosphoramidate.


AMP-thymidine kinase activity

description: Catalysis of the reaction: AMP + thymidine = adenosine + thymidine 5'-phosphate.


amygdalin beta-glucosidase activity

description: Catalysis of the reaction: (R)-amygdalin + H2O = (R)-prunasin + D-glucose.


amylosucrase activity

description: Catalysis of the reaction: sucrose + 1,4-alpha-D-glucosyl(n) = D-fructose + 1,4-alpha-D-glucosyl(n+1).


description: Catalysis of the reaction: anhydrotetracycline + H+ + NADPH + O2 = 12-dehydrotetracycline + H2O + NADP+.


cyclopeptine synthase activity

description: Catalysis of the reaction: anthranilate + 2 ATP + L-phenylalanine + S-adenosyl-L-methionine = 2 AMP + cyclopeptine + 2 diphosphate + 2 H+ + S-adenosyl-L-homocysteine.


description: Catalysis of the reaction: anthranilate + benzoyl-CoA = N-benzoylanthranilate + CoA.


description: Catalysis of the reaction: anthranilate + malonyl-CoA = N-malonylanthranilate + CoA.


apiose 1-reductase activity

description: Catalysis of the reaction: D-apiitol + NAD+ = D-apiose + H+ + NADH.


arabinonate dehydratase activity

description: Catalysis of the reaction: D-arabinonate = 2-dehydro-3-deoxy-D-arabinonate + H2O.


arachidonate-CoA ligase activity

description: Catalysis of the reaction: arachidonate + ATP + CoA = AMP + arachidonoyl-CoA + diphosphate + H+.


arachidonate 8(R)-lipoxygenase activity

description: Catalysis of the reaction: arachidonate + O2 = (5Z,8R,9E,11Z,14Z)-8-hydroperoxyicosa-5,9,11,14-tetraenoate.


arginine 2-monooxygenase activity

description: Catalysis of the reaction: L-arginine + O2 = 4-guanidinobutanamide + CO2 + H2O.


arginine racemase activity

description: Catalysis of the reaction: L-arginine = D-arginine.


aryl-acylamidase activity

description: Catalysis of the reaction: anilide + H2O = a carboxylate + aniline + H+.


name: aryl-alcohol dehydrogenase (NADP+) activity

description: Catalysis of the reaction: an aromatic alcohol + NADP+ = an aromatic aldehyde + NADPH.


aryl-alcohol oxidase activity

description: Catalysis of the reaction: an aromatic primary alcohol + O2 = an aromatic aldehyde + H2O2.


name: aryl-aldehyde dehydrogenase (NADP+) activity

description: Catalysis of the reaction: an aromatic aldehyde + NADP+ + AMP + diphosphate + H2O = an aromatic acid + NADPH + ATP.


arylamine glucosyltransferase activity

description: Catalysis of the reaction: UDP-glucose + an arylamine = UDP + an N-D-glucosylarylamine.


amine sulfotransferase activity

description: Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + an amine = adenosine 3',5'-bisphosphate + a sulfamate.


arylsulfate sulfotransferase activity

description: Catalysis of the reaction: an aryl sulfate + a phenol = a phenol + an aryl sulfate.


aspartate 4-decarboxylase activity

description: Catalysis of the reaction: L-aspartate = L-alanine + CO2.


aspartate racemase activity

description: Catalysis of the reaction: L-aspartate = D-aspartate.


description: Catalysis of the reaction: aspulvinone E + 2 dimethylallyl diphosphate = aspulvinone H + 2 diphosphate.


ATP deaminase activity

description: Catalysis of the reaction: ATP + H2O = ITP + NH3.


ATP diphosphatase activity

description: Catalysis of the reaction: ATP + H2O = AMP + H+ + diphosphate.


barbiturase activity

description: Catalysis of the reaction: barbiturate + H2O = malonate + urea.


benzoin aldolase activity

description: Catalysis of the reaction: benzoin = 2 benzaldehyde.


name: beta-adrenergic receptor kinase activity

description: Catalysis of the reaction: ATP + beta-adrenergic receptor = ADP + phospho-beta-adrenergic receptor.


beta-alanopine dehydrogenase activity

description: Catalysis of the reaction: (R)-beta-alanopine + H2O + NAD+ = beta-alanine + H+ + NADH + pyruvate.


beta-alanyl-CoA ammonia-lyase activity

description: Catalysis of the reaction: beta-alanyl-CoA = acryloyl-CoA + NH3.


beta-diketone hydrolase activity

description: Catalysis of the reaction: H2O + nonane-4,6-dione = butanoate + H+ + pentan-2-one.


beta-glucoside kinase activity

description: Catalysis of the reaction: ATP + cellobiose = ADP + 6-phospho-beta-D-glucosyl-(1,4)-D-glucose.


beta-L-arabinosidase activity

description: Catalysis of the reaction: H2O + a beta-L-arabinoside = L-arabinose + an alcohol.


beta-nitroacrylate reductase activity

description: Catalysis of the reaction: 3-nitropropanoate + NADP+ = 3-nitroacrylate + H+ + NADPH.


bile-salt sulfotransferase activity

description: Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + taurolithocholate = adenosine 3',5'-bisphosphate + taurolithocholate sulfate.


bilirubin oxidase activity

description: Catalysis of the reaction: 2 bilirubin + O2 = 2 biliverdin + 2 H2O.


biochanin-A reductase activity

description: Catalysis of the reaction: dihydrobiochanin A + NADP+ = biochanin A + H+ + NADPH.


biotin-CoA ligase activity

description: Catalysis of the reaction: ATP + biotin + CoA = AMP + diphosphate + biotinyl-CoA.


biotinidase activity

description: Catalysis of the reaction: biotin amide + H2O = biotin + NH3.


description: Catalysis of the reaction: bis(2-ethylhexyl)phthalate + H2O = 2-ethylhexan-1-ol + 2-ethylhexyl phthalate + H+.


description: Catalysis of the reaction: P(1),P(3)-bis(5'-adenosyl) triphosphate + H2O = ADP + AMP + 2 H+.


blasticidin-S deaminase activity

description: Catalysis of the reaction: blasticidin S + H2O = deaminohydroxyblasticidin S + NH3.


description: Catalysis of the reaction: Cypridina luciferin + O2 = oxidized Cypridina luciferin + CO2 + light.


galactitol 2-dehydrogenase activity

description: Catalysis of the reaction: galactitol + NAD+ = D-tagatose + H+ + NADH.


galactolipase activity

description: Catalysis of the reaction: 1,2-diacyl-3-beta-D-galactosyl-sn-glycerol + 2 H2O = 3-beta-D-galactosyl-sn-glycerol + 2 carboxylates.


hypotaurocyamine kinase activity

description: Catalysis of the reaction: ATP + hypotaurocyamine = N(omega)-phosphohypotaurocyamine + ADP + 2 H+.


imidazole N-acetyltransferase activity

description: Catalysis of the reaction: 1H-imidazole + acetyl-CoA = N-acetylimidazole + CoA.


description: Catalysis of the reaction: H+ + imidazol-4-ylacetate + NADH + O2 = 5-hydroxyimidazole-4-acetate + H2O + NAD+.


indanol dehydrogenase activity

description: Catalysis of the reaction: indan-1-ol + NAD(P)+ = indanone + NAD(P)H + H+.


indole 2,3-dioxygenase activity

description: Catalysis of the reaction: indole + O2 = 2-formamidobenzaldehyde.


indoleacetaldoxime dehydratase activity

description: Catalysis of the reaction: (indol-3-yl)acetaldehyde oxime = (indol-3-yl)acetonitrile + H2O.


description: Catalysis of the reaction: (indol-3-yl)acetate + L-lysine + ATP = N(6)-[(indole-3-yl)acetyl]-L-lysine + ADP + 2 H+ + phosphate.


name: indolelactate dehydrogenase (NAD+) activity

description: Catalysis of the reaction: 3-(indol-3-yl)lactate + NAD+ = 3-(indol-3-yl)pyruvate + H+ + NADH.


inosinate nucleosidase activity

description: Catalysis of the reaction: H2O + IMP = D-ribose 5-phosphate + hypoxanthine.


inosine nucleosidase activity

description: Catalysis of the reaction: inosine + H2O = D-ribose + hypoxanthine.


inulosucrase activity

description: Catalysis of the reaction: sucrose + 2,1-beta-D-fructosyl(n) = glucose + 2,1-beta-D-fructosyl(n+1).


iron-cytochrome-c reductase activity

description: Catalysis of the reaction: ferrocytochrome c + Fe3+ = ferricytochrome c + Fe2+.


isobutyryl-CoA mutase activity

description: Catalysis of the reaction: isobutyryl-CoA = butanoyl-CoA.


carnitine 3-dehydrogenase activity

description: Catalysis of the reaction: carnitine + NAD+ = 3-dehydrocarnitine + H+ + NADH.


carnitine decarboxylase activity

description: Catalysis of the reaction: carnitine + H+ = 2-methylcholine + CO2.


carnosine synthase activity

description: Catalysis of the reaction: ATP + L-histidine + beta-alanine = AMP + diphosphate + carnosine.


catechol oxidase (dimerizing) activity

description: Catalysis of the reaction: 4 catechol + 3 O2 = 2 dibenzo[1,4]dioxin-2,3-dione + 6 H2O.


CDP-abequose epimerase activity

description: Catalysis of the reaction: CDP-3,6-dideoxy-D-glucose = CDP-3,6-dideoxy-D-mannose.


CDP-glucose 4,6-dehydratase activity

description: Catalysis of the reaction: CDP-D-glucose = CDP-4-dehydro-6-deoxy-D-glucose + H2O.


CDP-glycerol diphosphatase activity

description: Catalysis of the reaction: CDP-glycerol + H2O = sn-glycerol 3-phosphate + CMP + 2 H+.


name: cellobiose dehydrogenase (acceptor) activity

description: Catalysis of the reaction: cellobiose + acceptor = cellobiono-1,5-lactone + reduced acceptor.


cellobiose epimerase activity

description: Catalysis of the reaction: cellobiose = D-glucosyl-D-mannose.


cellobiose phosphorylase activity

description: Catalysis of the reaction: cellobiose + phosphate = alpha-D-glucose 1-phosphate + D-glucose.


cephalosporin-C deacetylase activity

description: Catalysis of the reaction: cephalosporin C + H2O = acetate + deacetylcephalosporin C + H+.


cephalosporin-C transaminase activity

description: Catalysis of the reaction: (7R)-7-(5-carboxylato-5-oxopentanamido)deacetylcephalosporanate + D-glutamate = 2-oxoglutarate + cephalosporin C.


cetraxate benzylesterase activity

description: Catalysis of the reaction: benzyl cetraxate + H2O = benzyl alcohol + cetraxate + H+.


description: Catalysis of the reaction: chenodeoxycholoyltaurine + H2O = chenodeoxycholate + taurine.


chlordecone reductase activity

description: Catalysis of the reaction: chlordecone alcohol + NADP+ = chlordecone + H+ + NADPH.


description: Catalysis of the reaction: 5-amino-4-chloro-2-(2,3-dihydroxyphenyl)pyridazin-3(2H)-one + O2 = 5-amino-4-chloro-2-(2-hydroxymuconoyl)pyridazin-3(2H)-one + 2 H+.


chlorogenate hydrolase activity

description: Catalysis of the reaction: chlorogenate + H2O = (-)-quinate + cis-caffeate + H+.


chlorophyllase activity

description: Catalysis of the reaction: chlorophyll + H2O = phytol + chlorophyllide.


cholate-CoA ligase activity

description: Catalysis of the reactions: (1) ATP + cholate + CoA = AMP + diphosphate + choloyl-CoA and (2) ATP + (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oate + CoA = AMP + diphosphate + (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA. This reaction is the first step in the conjugation of bile acids with amino acids, converting bile acids into their acyl-CoA thioesters. Chenodeoxycholate, deoxycholate, lithocholate and trihydroxycoprostanoate can also act as substrates.


description: Catalysis of the reaction: 5-beta-cholestane-3-alpha,7-alpha,12-alpha,26-tetraol + NAD+ = 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestan-26-al + NADH.


cholestenol delta-isomerase activity

description: Catalysis of the reaction: 5-alpha-cholest-7-en-3-beta-ol = 5-alpha-cholest-8-en-3-beta-ol.


name: 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+) activity

description: Catalysis of the reaction: 3-oxo-5alpha-steroid + NADP+ = a 3-oxo-delta(4)-steroid + H+ + NADPH.


choline-sulfatase activity

description: Catalysis of the reaction: choline sulfate + H2O = choline + H+ + sulfate.


choline sulfotransferase activity

description: Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + choline = adenosine 3',5'-diphosphate + choline sulfate + H+.


isocitrate epimerase activity

description: Catalysis of the reaction: D-threo-isocitrate = D-erythro-isocitrate.


chondroitin 4-sulfotransferase activity

description: Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + chondroitin = adenosine 3',5'-bisphosphate + chondroitin 4'-sulfate.


description: Catalysis of the reaction: chondroitin D-glucuronate = dermatan L-iduronate.


description: Catalysis of the reaction: 2-methylpropanoate + ATP = 2-methylpropanoyl phosphate + ADP + H+.


butanal dehydrogenase activity

description: Catalysis of the reaction: butanal + CoA + NAD(P)+ = butanoyl-CoA + NAD(P)H + H+.


butyrate kinase activity

description: Catalysis of the reaction: ATP + butanoate = ADP + butanoyl phosphate + H+.


caffeate 3,4-dioxygenase activity

description: Catalysis of the reaction: trans-caffeate + O2 = 3-(2-carboxyethenyl)-cis,cis-muconate + 2 H+.


caffeate O-methyltransferase activity

description: Catalysis of the reaction: S-adenosyl-L-methionine + 3,4-dihydroxy-trans-cinnamate = S-adenosyl-L-homocysteine + 3-methoxy-4-hydroxy-trans-cinnamate.


carbamoyl-serine ammonia-lyase activity

description: Catalysis of the reaction: O-carbamoyl-L-serine + H2O + H+ = CO2 + 2 NH4 + pyruvate.


description: Catalysis of the reaction: 3-carboxy-2,5-dihydro-5-oxofuran-2-acetate = 3-carboxy-cis,cis-muconate.


arogenate dehydratase activity

description: Catalysis of the reaction: L-arogenate = L-phenylalanine + H2O + CO2.


carboxylate reductase activity

description: Catalysis of the reaction: an aldehyde + acceptor + H2O = a carboxylate + reduced acceptor.


carboxymethylhydantoinase activity

description: Catalysis of the reaction: L-5-carboxymethylhydantoin + H2O = N-carbamoyl-L-aspartate + H+.


description: Catalysis of the reaction: carboxymethoxysuccinate = fumarate + glycolate.


carnitinamidase activity

description: Catalysis of the reaction: (R)-carnitinamide + H2O = (R)-carnitine + NH4.


name: cis-2-enoyl-CoA reductase (NADPH) activity

description: Catalysis of the reaction: acyl-CoA + NADP+ = cis-2,3-dehydroacyl-CoA + NADPH.


citramalate CoA-transferase activity

description: Catalysis of the reaction: acetyl-CoA + citramalate = acetate + (3S)-citramalyl-CoA.


citramalate lyase activity

description: Catalysis of the reaction: S-citramalate = acetate + pyruvate.


(S)-citramalyl-CoA lyase activity

description: Catalysis of the reaction: (3S)-citramalyl-CoA = acetyl-CoA + pyruvate.


description: Catalysis of the reaction: [citrate (pro-3S)-lyase](acetyl form) + H2O = [citrate (pro-3S)-lyase](thiol form) + acetate.


citrate-CoA ligase activity

description: Catalysis of the reaction: ATP + citrate + CoA = (3S)-citryl-CoA + ADP + H+ + phosphate.


citrullinase activity

description: Catalysis of the reaction: H2O + citrulline = NH3 + CO2 + L-ornithine.


coniferin beta-glucosidase activity

description: Catalysis of the reaction: H2O + coniferin = D-glucose + coniferol.


description: Catalysis of the reaction: corticosterone + reduced adrenal ferredoxin + O2 = 18-hydroxycorticosterone + oxidized adrenal ferredoxin + H2O.


cortisol O-acetyltransferase activity

description: Catalysis of the reaction: acetyl-CoA + cortisol = CoA + cortisol 21-acetate.


cortisol sulfotransferase activity

description: Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + cortisol = adenosine 3',5'-diphosphate + cortisol 21-sulfate + H+.


description: Catalysis of the reaction: a 3-oxo-5beta-steroid + NADP+ = a 3-oxo-Delta(4)-steroid + H+ + NADPH. The enzyme from human efficiently catalyzes the reduction of progesterone, androstenedione, 17alpha-hydroxyprogesterone and testosterone to 5beta-reduced metabolites; it can also act on aldosterone, corticosterone and cortisol, but to a lesser extent. The bile acid intermediates 7alpha,12alpha-dihydroxy-4-cholesten-3- one and 7alpha-hydroxy-4-cholesten-3-one can also act as substrates.


2-coumarate reductase activity

description: Catalysis of the reaction: 3-(2-hydroxyphenyl)propanoate + NAD+ = trans-2-coumarate + H+ + NADH.


creatininase activity

description: Catalysis of the reaction: creatinine + H2O = creatine.


creatinine deaminase activity

description: Catalysis of the reaction: creatinine + H2O = N-methylhydantoin + NH3.


cucurbitacin delta23-reductase activity

description: Catalysis of the reaction: 23,24-dihydrocucurbitacin + NAD(P)+ = cucurbitacin + NAD(P)H + H+.


description: Catalysis of the reaction: UDP-glucose + (S)-4-hydroxymandelonitrile = UDP + (S)-4-hydroxy-mandelonitrile beta-D-glucoside.


cycloeucalenol cycloisomerase activity

description: Catalysis of the reaction: cycloeucalenol = obtusifoliol.


cyclohexadienyl dehydrogenase activity

description: Catalysis of the reaction: L-arogenate + NAD+ = L-tyrosine + NADH + CO2.


description: Catalysis of the reaction: trans-cyclohexane-1,2-diol + NAD+ = 2-hydroxycyclohexan-1-one + NADH.


description: Catalysis of the reaction: cyclohexane-1,3-dione + H2O = 5-oxohexanoate + H+.


cyclohexanone dehydrogenase activity

description: Catalysis of the reaction: A + cyclohexanone = AH(2) + cyclohex-2-enone.


cyclomaltodextrinase activity

description: Catalysis of the reaction: H2O + cyclomaltodextrin = linear maltodextrin.


cyclopentanone monooxygenase activity

description: Catalysis of the reaction: cyclopentanone + H+ + NADPH + O2 = 5-valerolactone + H2O + NADP+.


cysteamine dioxygenase activity

description: Catalysis of the reaction: cysteamine + O2 = H+ + hypotaurine.


L-cysteine transaminase activity

description: Catalysis of the reaction: L-cysteine + 2-oxoglutarate = mercaptopyruvate + L-glutamate.


description: Catalysis of the reaction: 2-oxoglutarate + S-(4-bromophenyl)-L-cysteine = (4-bromophenylsulfanyl)pyruvate + L-glutamate.


cysteine lyase activity

description: Catalysis of the reaction: L-cysteine + sulfite = L-cysteate + sulfide.


description: Catalysis of the reaction: S-substituted L-cysteine + H2O = a thiol + NH4+ + pyruvate.


cytidylate cyclase activity

description: Catalysis of the reaction: CTP = 3',5'-cyclic CMP + diphosphate + H+.


cytochrome-c3 hydrogenase activity

description: Catalysis of the reaction: 2 H2 + ferricytochrome c3 = 4 H+ + ferrocytochrome c3.


description: Catalysis of the reaction: 6-alkylaminopurine + UDP-D-glucose = 6-alkylamino-7-beta-D-glucosylpurine + H+ + UDP. This reaction is an N-glucosylation event.


D(-)-tartrate dehydratase activity

description: Catalysis of the reaction: D-tartrate = H2O + oxaloacetate.


D-2-hydroxy-acid dehydrogenase activity

description: Catalysis of the reaction: (R)-lactate + A = AH(2) + pyruvate.


description: Catalysis of the reaction: D-alanine + 2-oxoglutarate = pyruvate + D-glutamate.


description: Catalysis of the reaction: D-alanine + L-glutamine = gamma-L-glutamyl-D-alanine + NH4.


description: Catalysis of the reaction: acetyl-CoA + a D-amino acid = CoA + an N-acetyl-D-amino-acid.


D-arabinitol 4-dehydrogenase activity

description: Catalysis of the reaction: D-arabinitol + NAD+ = D-xylulose + NADH.


D-arabinokinase activity

description: Catalysis of the reaction: D-arabinose + ATP = D-arabinose 5-phosphate + ADP.


D-arabinonolactonase activity

description: Catalysis of the reaction: D-arabinono-1,4-lactone + H2O = D-arabinonate + H+.


name: D-arabinose 1-dehydrogenase (NAD+) activity

description: Catalysis of the reaction: D-arabinose + NAD+ = D-arabinono-1,4-lactone + NADH.


D-arginase activity

description: Catalysis of the reaction: D-arginine + H2O = D-ornithine + urea.


D-fuconate dehydratase activity

description: Catalysis of the reaction: D-fuconate = 2-dehydro-3-deoxy-D-fuconate + H2O.


description: Catalysis of the reaction: D-glutamate + H2O + O2 = 2-oxoglutarate + NH3 + H2O2, and D-aspartate + H2O + O2 = oxaloacetate + NH3 + H2O2.


D-glutamate cyclase activity

description: Catalysis of the reaction: D-glutamate = 5-oxo-D-proline + H2O.


D-glutamate oxidase activity

description: Catalysis of the reaction: D-glutamate + H2O + O2 = 2-oxoglutarate + NH3 + H2O2.


hypotaurine dehydrogenase activity

description: Catalysis of the reaction: H+ + hypotaurine + NADPH + O2 = H2O + NADP+ + taurine.


D-glutamyltransferase activity

description: Catalysis of the reaction: D-glutamate + D-glutamine = gamma-D-glutamyl-D-glutamate + NH4+. Can also transfer additional glutamyl residues to a peptide, extending the polypeptide chain.


D-iditol 2-dehydrogenase activity

description: Catalysis of the reaction: D-iditol + NAD+ = D-sorbose + NADH.


D-lactate-2-sulfatase activity

description: Catalysis of the reaction: (R)-2-O-sulfolactate + H2O = (R)-lactate + H+ + sulfate.


D-lysine 5,6-aminomutase activity

description: Catalysis of the reaction: D-lysine = (2R,5S)-2,5-diaminohexanoate and (3S)-3,6-diaminohexanoate = (3S,5S)-3,5-diaminohexanoate.


D-lysopine dehydrogenase activity

description: Catalysis of the reaction: D-lysopine + H2O + NADP+ = L-lysine + H+ + NADPH + pyruvate.


D-lyxose ketol-isomerase activity

description: Catalysis of the reaction: D-lyxose = D-xylulose.


D-nopaline dehydrogenase activity

description: Catalysis of the reaction: N2-(D-1,3-dicarboxypropyl)-L-arginine + NADP+ + H2O = L-arginine + 2-oxoglutarate + NADPH.


D-octopine dehydrogenase activity

description: Catalysis of the reaction: N2-(D-1-carboxyethyl)-L-arginine + NAD+ + H2O = L-arginine + pyruvate + NADH.


D-ornithine 4,5-aminomutase activity

description: Catalysis of the reaction: D-ornithine = (2R,4S)-2,4-diaminopentanoate.


D-pinitol dehydrogenase activity

description: Catalysis of the reaction: 5D-5-O-methyl-chiro-inositol + NADP+ = 2D-5-O-methyl-2,3,5/4,6-pentahydroxycyclohexanone + H+ + NADPH.


name: D-sorbitol dehydrogenase (acceptor) activity

description: Catalysis of the reaction: D-sorbitol + acceptor = L-sorbose + reduced acceptor.


D-threo-aldose 1-dehydrogenase activity

description: Catalysis of the reaction: a D-threo-aldose + NAD+ = a D-threo-aldono-1,5-lactone + NADH.


description: Catalysis of the reaction: D-tryptophan + acetyl-CoA = N-acetyl-D-tryptophan + CoA + H+.


description: Catalysis of the reaction: D-tryptophan + malonyl-CoA = N(2)-malonyl-D-tryptophan + CoA + H+.


name: D-xylose 1-dehydrogenase (NADP+) activity

description: Catalysis of the reaction: D-xylose + NADP+ = D-xylono-1,5-lactone + H+ + NADPH.


name: D-xylose 1-dehydrogenase (NAD+) activity

description: Catalysis of the reaction: D-xylose + NAD+ = D-xylonolactone + NADH.


description: Catalysis of the reaction: dATP + depurinated DNA = ribose triphosphate + DNA.


dCTP diphosphatase activity

description: Catalysis of the reaction: dCTP + H2O = dCMP + H+ + diphosphate.


dehydrogluconokinase activity

description: Catalysis of the reaction: 2-dehydro-D-gluconate + ATP = 6-phospho-2-dehydro-D-gluconate + ADP + 2 H+.


description: Catalysis of the reaction: 3-dehydro-L-gulonate + H+ = L-xylulose + CO2.


dehydrogluconate dehydrogenase activity

description: Catalysis of the reaction: 2-dehydro-D-gluconate + A = 2,5-didehydro-D-gluconate + AH(2).


deoxylimonate A-ring-lactonase activity

description: Catalysis of the reaction: deoxylimonoate + H2O = deoxylimononate D-ring-lactone + H+.


deoxynucleotide 3'-phosphatase activity

description: Catalysis of the reaction: a deoxynucleoside 3'-phosphate + H2O = a deoxynucleoside + phosphate.


deoxyuridine phosphorylase activity

description: Catalysis of the reaction: 2'-deoxyuridine + phosphate = 2-deoxy-alpha-D-ribose 1-phosphate + uracil.


name: dephospho-[reductase kinase] kinase activity

description: Catalysis of the reaction: ATP + dephospho-[[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase] = ADP + [[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase].


dextransucrase activity

description: Catalysis of the reaction: sucrose + 1,6-alpha-D-glucosyl(n) = D-fructose + 1,6-alpha-D-glucosyl(n+1).


diaminopimelate dehydrogenase activity

description: Catalysis of the reaction: meso-2,6-diaminopimelate + H2O + NADP+ = L-2-amino-6-oxopimelate + H+ + NADPH + NH4.


dicarboxylate-CoA ligase activity

description: Catalysis of the reaction: ATP + an omega-dicarboxylic acid + CoASH= AMP + diphosphate + an omega-carboxyacyl-CoA.


diferric-transferrin reductase activity

description: Catalysis of the reaction: transferrin[Fe2+]2 + NAD+ = transferrin[Fe3+]2 + NADH.


difructose-anhydride synthase activity

description: Catalysis of the reaction: H2O + bis-D-fructose 2',1:2,1'-dianhydride = inulobiose.


diguanidinobutanase activity

description: Catalysis of the reaction: 1,4-diguanidinobutane + H2O = agmatine + urea.


dihydrobunolol dehydrogenase activity

description: Catalysis of the reaction: dihydrobunolol + NADP+ = bunolol + H+ + NADPH.


dihydrocoumarin hydrolase activity

description: Catalysis of the reaction: 3,4-dihydrocoumarin + H2O = 3-(2-hydroxyphenyl)propanoate + H+.


dihydrouracil oxidase activity

description: Catalysis of the reaction: 5,6-dihydrouracil + O2 = H2O2 + uracil.


description: Catalysis of the reaction: dihydroxyfumarate + H+ = 2-hydroxy-3-oxopropanoate + CO2.


diiodophenylpyruvate reductase activity

description: Catalysis of the reaction: 3-(3,5-diiodo-4-hydroxyphenyl)lactate + NAD+ = 3-(3,5-diiodo-4-hydroxyphenyl)pyruvate + H+ + NADH.


diiodotyrosine transaminase activity

description: Catalysis of the reaction: 2-oxoglutarate + 3,5-diiodo-L-tyrosine = 3-(3,5-diiodo-4-hydroxyphenyl)pyruvate + L-glutamate.


diisopropyl-fluorophosphatase activity

description: Catalysis of the reaction: diisopropyl fluorophosphate + H2O = diisopropyl phosphate + fluoride + 2 H+.


dimethylallylcistransferase activity

description: Catalysis of the reaction: dimethylallyl diphosphate + isopentenyl diphosphate = diphosphate + neryl diphosphate.


description: Catalysis of the reaction: N,N-dimethylaniline N-oxide = N-methylaniline + formaldehyde.


dimethylglycine dehydrogenase activity

description: Catalysis of the reaction: N,N-dimethylglycine + electron-transfer flavoprotein + H2O = sarcosine + formaldehyde + reduced electron-transfer flavoprotein.


dimethylglycine oxidase activity

description: Catalysis of the reaction: N,N-dimethylglycine + H2O + O2 = formaldehyde + H2O2 + sarcosine.


dimethylmalate dehydrogenase activity

description: Catalysis of the reaction: (R)-3,3-dimethylmalate + NAD+ = 3-methyl-2-oxobutanoate + CO2 + NADH.


dimethylmaleate hydratase activity

description: Catalysis of the reaction: (2R,3S)-2,3-dimethylmalate = dimethylmaleate + H2O.


description: Catalysis of the reaction: S,S-dimethyl-beta-propiothetin = acrylate + dimethyl sulfide + H+.


discadenine synthase activity

description: Catalysis of the reaction: N(6)-dimethylallyladenine + S-adenosyl-L-methionine(1+) = S-methyl-5'-thioadenosine + discadenine + H+.


disulfoglucosamine-6-sulfatase activity

description: Catalysis of the reaction: N(2),6-disulfo-D-glucosamine + H2O = N-sulfo-D-glucosamine + H+ + sulfate.


dolichol O-acyltransferase activity

description: Catalysis of the reaction: palmitoyl-CoA + dolichol = CoA + dolichyl palmitate.


dolichyl-phosphatase activity

description: Catalysis of the reaction: dolichyl phosphate + H2O = dolichol + phosphate.


dolichyldiphosphatase activity

description: Catalysis of the reaction: dolichyl diphosphate + H2O = dolichyl phosphate + phosphate.


ecdysone oxidase activity

description: Catalysis of the reaction: Ecdysone + O2 = 3-dehydroecdysone + H2O2.


endoglycosylceramidase activity

description: Catalysis of the reaction: H2O + oligoglycosylglucosylceramide = ceramide + oligoglycosylglucose.


ephedrine dehydrogenase activity

description: Catalysis of the reaction: (1R,2S)-ephedrine + NAD+ = (R)-2-methylimino-1-phenylpropan-1-ol + 2 H+ + NADH.


erythritol kinase activity

description: Catalysis of the reaction: ATP + erythritol = D-erythritol 4-phosphate + ADP + 2 H+.


erythronolide synthase activity

description: Catalysis of the reaction: 6 malonyl-CoA + propionyl-CoA = 7 CoA + 6-deoxyerythronolide B.


erythrulose reductase activity

description: Catalysis of the reaction: D-threitol + NADP+ = D-erythrulose + H+ + NADPH.


name: estradiol 17-alpha-dehydrogenase [NAD(P)+] activity

description: Catalysis of the reaction: estradiol-17-alpha + NAD(P)+ = estrone + NAD(P)H + H+.


estradiol 6-beta-monooxygenase activity

description: Catalysis of the reaction: AH(2) + estradiol-17beta + O2 = 6beta-hydroxyestradiol-17beta + A + H2O.


ethanolamine oxidase activity

description: Catalysis of the reaction: ethanolamine + H2O + O2 = glycolaldehyde + NH3 + H2O2.


FAD diphosphatase activity

description: Catalysis of the reaction: FAD + H2O = AMP + FMN.


farnesol 2-isomerase activity

description: Catalysis of the reaction: 2-trans,6-trans-farnesol = 2-cis,6-trans-farnesol.


farnesol dehydrogenase activity

description: Catalysis of the reaction: 2-trans,6-trans-farnesol + NADP+ = 2-trans,6-trans-farnesal + H+ + NADPH.


farnesyl diphosphate kinase activity

description: Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate + ATP = 2-trans,6-trans-farnesyl triphosphate + ADP.


fatty acid peroxidase activity

description: Catalysis of the reaction: 2 H2O2 + H+ + palmitate = CO2 + 3 H2O + pentadecanal.


ferredoxin-nitrate reductase activity

description: Catalysis of the reaction: nitrite + H2O + 2 oxidized ferredoxin = nitrate + 2 reduced ferredoxin.


flavanone 4-reductase activity

description: Catalysis of the reaction: (2S)-flavan-4-ol + NADP+ = (2S)-flavanone + NADPH.


description: Catalysis of the reaction: UDP-glucose + 5,7,3',4'-tetrahydroxyflavone = UDP + 7-O-beta-D-glucosyl-5,7,3',4'-tetrahydroxyflavone.


flavone apiosyltransferase activity

description: Catalysis of the reaction: UDP-apiose + 7-O-beta-D-glucosyl-5,7,4'-trihydroxyflavone = UDP + 7-O-(beta-D-apiofuranosyl-1,2-beta-D-glucosyl)-5,7,4'-trihydroxyflavone.


description: Catalysis of the reaction: UDP-glucose + a flavonol = UDP + a flavonol 3-O-D-glucoside.


flavonol 3-sulfotransferase activity

description: Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + quercetin = adenosine 3',5'-diphosphate + H+ + quercetin 3-sulfate.


formaldehyde dismutase activity

description: Catalysis of the reaction: 2 formaldehyde + H2O = methanol + formate.


formaldehyde transketolase activity

description: Catalysis of the reaction: D-xylulose 5-phosphate + formaldehyde = glyceraldehyde 3-phosphate + glycerone.


formate-dihydrofolate ligase activity

description: Catalysis of the reaction: 7,8-dihydrofolate + ATP + formate = 10-formyldihydrofolate + ADP + H+ + phosphate.


name: formate dehydrogenase (cytochrome) activity

description: Catalysis of the reaction: formate + ferricytochrome b1 = CO2 + ferrocytochrome b1.


formate dehydrogenase (NADP+) activity

description: Catalysis of the reaction: formate + NADP+ = CO2 + NADPH.


formate kinase activity

description: Catalysis of the reaction: ATP + formate = ADP + formyl phosphate + H+.


formylaspartate deformylase activity

description: Catalysis of the reaction: N-formyl-L-aspartate + H2O = formate + L-aspartate.


name: fructose 5-dehydrogenase (NADP+) activity

description: Catalysis of the reaction: D-fructose + NADP+ = 5-dehydro-D-fructose + NADPH.


fructose 5-dehydrogenase activity

description: Catalysis of the reaction: a ubiquinone + keto-D-fructose = 5-dehydro-D-fructose + a ubiquinol.


description: Catalysis of the reaction: D-fructose 6-phosphate + phosphate = acetyl phosphate + D-erythrose 4-phosphate + H2O.


fucosterol-epoxide lyase activity

description: Catalysis of the reaction: (24R,24'R)-fucosterol epoxide = acetaldehyde + desmosterol.


furylfuramide isomerase activity

description: Catalysis of the reaction: (E)-2-(2-furyl)-3-(5-nitro-2-furyl)acrylamide = (Z)-2-(2-furyl)-3-(5-nitro-2-furyl)acrylamide.


fusarinine-C ornithinesterase activity

description: Catalysis of the reaction: N5-acyl-L-ornithine ester + H2O = N5-acyl-L-ornithine + an alcohol.


galactolipid O-acyltransferase activity

description: Catalysis of the reaction: 2 mono-beta-D-galactosyldiacylglycerol = acylmono-beta-D-galactosyl-diacylglycerol + mono-beta-D-galactosylacylglycerol.


name: galactose 1-dehydrogenase (NADP+) activity

description: Catalysis of the reaction: D-galactose + NADP+ = D-galactonolactone + NADPH.


description: Catalysis of the reaction: [(1->4)-alpha-D-galacturonide](n) + H2O = [(1->4)-alpha-D-galacturonide](n-1) + D-galacturonate.


galacturonokinase activity

description: Catalysis of the reaction: alpha-D-galacturonate + ATP = 1-phospho-alpha-D-galacturonate + ADP + 2 H+.


description: Catalysis of the reaction: gallate + UDP-D-glucose = 1-O-galloyl-beta-D-glucose + UDP.


description: Catalysis of the reaction: histamine + L-glutamate + ATP = N(alpha)-gamma-L-glutamylhistamine + products of ATP breakdown.


description: Catalysis of the reaction: UDP-galactose + N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-1,4-beta-D-glucosyl-N-acylsphingosine = UDP + D-galactosyl-1,3-beta-N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosyl-N-acylsphingosine.


description: Catalysis of the reaction: GDP-6-deoxy-D-talose + NAD(P)+ = GDP-4-dehydro-6-deoxy-D-talose + NAD(P)H + H+.


GDP-glucosidase activity

description: Catalysis of the reaction: GDP-D-glucose + H2O = D-glucose + GDP + H+.


GDP-mannose 3,5-epimerase activity

description: Catalysis of the reaction: GDP-mannose = GDP-L-galactose.


GDP-mannose 6-dehydrogenase activity

description: Catalysis of the reaction: GDP-alpha-D-mannose + H2O + 2 NAD+ = GDP-D-mannuronate + 3 H+ + 2 NADH.


geissoschizine dehydrogenase activity

description: Catalysis of the reaction: geissoschizine + NADP+ = 4,21-dehydrogeissoschizine + H+ + NADPH.


description: Catalysis of the reaction: acetyl-CoA + gentamicin C(1a) = N(2')-acetylgentamicin C(1a) + CoA + H+. This is acetylation of the 2'-amino group of the 6-deoxy-6-aminoglucose ring.


gentisate 1,2-dioxygenase activity

description: Catalysis of the reaction: 2,5-dihydroxybenzoate + O2 = 3-maleylpyruvate + H+.


gentisate decarboxylase activity

description: Catalysis of the reaction: 2,5-dihydroxybenzoate + H+ = CO2 + hydroquinone.


geraniol dehydrogenase activity

description: Catalysis of the reaction: geraniol + NADP+ = geranial + NADPH.


geranoyl-CoA carboxylase activity

description: Catalysis of the reaction: ATP + bicarbonate + geranoyl-CoA = 3-(4-methylpent-3-en-1-yl)pent-2-enedioyl-CoA + ADP + 2 H+ + phosphate.


geranyl-diphosphate cyclase activity

description: Catalysis of the reaction: geranyl diphosphate = (2S)-bornyl diphosphate.


gibberellin-44 dioxygenase activity

description: Catalysis of the reaction: gibberellin 44 + 2-oxoglutarate + O2 = gibberellin 19 + succinate + CO2.


description: Catalysis of the reaction: UDP-glucose + gibberellin = UDP + gibberellin 2-O-beta-D-glucoside.


gluconate dehydratase activity

description: Catalysis of the reaction: D-gluconate = 2-dehydro-3-deoxy-D-gluconate + H2O.


glucosaminate ammonia-lyase activity

description: Catalysis of the reaction: D-glucosaminate = 2-dehydro-3-deoxy-D-gluconate + NH3.


glucosamine kinase activity

description: Catalysis of the reaction: ATP + D-glucosamine = ADP + D-glucosamine 6-phosphate + H+.


description: Catalysis of the reaction: D-glucosamine + acetyl-CoA = N-acetyl-D-glucosamine + CoA + H+.


description: Catalysis of the reaction: 3-phospho-D-glyceroyl phosphate + alpha-D-glucose 1-phosphate = 3-phospho-D-glycerate + alpha-D-glucose 1,6-bisphosphate + H+.


glucose 1-dehydrogenase (NAD+) activity

description: Catalysis of the reaction: D-glucose + NAD+ = D-glucono-1,5-lactone + NADH.


name: glucose 1-dehydrogenase (NADP+) activity

description: Catalysis of the reaction: D-glucose + NADP+ = D-glucono-1,5-lactone + NADPH.


name: glucose 1-dehydrogenase [NAD(P)+] activity

description: Catalysis of the reaction: beta-D-glucose + NAD(P)+ = D-glucono-1,5-lactone + NAD(P)H.


description: Catalysis of the reaction: 2 D-glucose 1-phosphate = D-glucose + D-glucose 1,6-bisphosphate.


description: Catalysis of the reaction: alpha-D-glucose 6-phosphate = beta-D-glucose 6-phosphate.


L-glucuronate reductase activity

description: Catalysis of the reaction: L-gulonate + NADP+ = D-glucuronate + H+ + NADPH.


glucuronokinase activity

description: Catalysis of the reaction: D-glucuronate + ATP = 1-phospho-alpha-D-glucuronate + ADP + 2 H+.


glucuronolactone reductase activity

description: Catalysis of the reaction: L-gulono-1,4-lactone + NADP+ = D-glucurono-3,6-lactone + H+ + NADPH.


glutamate-ethylamine ligase activity

description: Catalysis of the reaction: L-glutamate + ATP + ethylamine = N(5)-ethyl-L-glutamine + ADP + 2 H+ + phosphate.


glutamate-methylamine ligase activity

description: Catalysis of the reaction: L-glutamate + ATP + methylammonium = N(5)-methyl-L-glutamine + ADP + 2 H+ + phosphate.


description: Catalysis of the reaction: L-glutamine + pyruvate = 2-oxoglutaramate + L-alanine.


glutamine N-acyltransferase activity

description: Catalysis of the reaction: acyl-CoA + L-glutamine = CoA + N-acyl-L-glutamine.


description: Catalysis of the reaction: phenylacetyl-CoA + L-glutamine = CoA + alpha-N-phenylacetyl-L-glutamine.


glutarate-CoA ligase activity

description: Catalysis of the reaction: ATP + CoA + glutarate = ADP + glutaryl-CoA + H+ + phosphate.


glutathione oxidase activity

description: Catalysis of the reaction: 2 glutathione + O2 = glutathione disulfide + H2O2.


glutathione thiolesterase activity

description: Catalysis of the reaction: S-acylglutathione + H2O = a carboxylate + glutathione + H+.


name: glycerol-3-phosphate dehydrogenase [NAD(P)+] activity

description: Catalysis of the reaction: sn-glycerol 3-phosphate + NAD(P)+ = glycerone phosphate + NAD(P)H + H+.


name: glycerol 2-dehydrogenase (NADP+) activity

description: Catalysis of the reaction: glycerol + NADP+ = glycerone + H+ + NADPH.


glycerol-2-phosphatase activity

description: Catalysis of the reaction: glycerol 2-phosphate + H2O = glycerol + phosphate.


name: glycerol dehydrogenase (acceptor) activity

description: Catalysis of the reaction: A + glycerol = AH(2) + glycerone.


glycerol dehydrogenase (NADP+) activity

description: Catalysis of the reaction: glycerol + NADP+ = D-glyceraldehyde + NADPH.