name: regulation of conidiophore stalk development

description: Any process that modulates the frequency, rate or extent of conidiophore stalk development, a process that leads to the formation of a conidiophore stalk. The conidiophore stalk is part of a specialized hypha that extends aerially from the growth substrate and supports structures from which conidia, or asexual spores, develop.


name: negative regulation of conidiophore stalk development

category: biolink:BiologicalProcess biolink:Occurrent biolink:OntologyClass biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: Any process that stops, prevents, or reduces the frequency, rate or extent of conidiophore stalk development, a process that leads to the formation of a conidiophore stalk. The conidiophore stalk is part of a specialized hypha that extends aerially from the growth substrate and supports structures from which conidia, or asexual spores, develop.


name: positive regulation of conidiophore stalk development

description: Any process that activates or increases the frequency, rate or extent of conidiophore stalk development, a process that leads to the formation of a conidiophore stalk. The conidiophore stalk is part of a specialized hypha that extends aerially from the growth substrate and supports structures from which conidia, or asexual spores, develop.


regulation of metula development

description: Any process that modulates the frequency, rate or extent of metula development, a process that leads to the formation of metulae. Metulae are elongated mononucleate cells that bud from the surface of the conidiophore tip.


name: negative regulation of metula development

description: Any process that stops, prevents, or reduces the frequency, rate or extent of metula development, a process that leads to the formation of metulae. Metulae are elongated mononucleate cells that bud from the surface of the conidiophore tip.


name: positive regulation of metula development

description: Any process that activates or increases the frequency, rate or extent of metula development, a process that leads to the formation of metulae. Metulae are elongated mononucleate cells that bud from the surface of the conidiophore tip.


regulation of phialide development

description: Any process that modulates the frequency, rate or extent of phialide development, a process that leads to the formation of phialides. Phialides are specialized cells that bud from the ends of metulae on the conidiophore tip.


name: negative regulation of phialide development

description: Any process that stops, prevents, or reduces the frequency, rate or extent of phialide development, a process that leads to the formation of phialides. Phialides are specialized cells that bud from the ends of metulae on the conidiophore tip.


name: positive regulation of phialide development

description: Any process that activates or increases the frequency, rate or extent of phialide development, a process that leads to the formation of phialides. Phialides are specialized cells that bud from the ends of metulae on the conidiophore tip.


regulation of Hulle cell development

description: Any process that modulates the frequency, rate or extent of Hulle cell development, a process that leads to the formation of Hulle cells. Hulle cells are specialized multinucleate cells that originate from a nest-like aggregation of hyphae during sexual development and serve as nurse cells to the developing cleistothecium, or fruiting body.


name: negative regulation of Hulle cell development

description: Any process that stops, prevents, or reduces the frequency, rate or extent of Hulle cell development, a process that leads to the formation of Hulle cells. Hulle cells are specialized multinucleate cells that originate from a nest-like aggregation of hyphae during sexual development and serve as nurse cells to the developing cleistothecium, or fruiting body.


name: positive regulation of Hulle cell development

description: Any process that activates or increases the frequency, rate or extent of Hulle cell development, a process that leads to the formation of Hulle cells. Hulle cells are specialized multinucleate cells that originate from a nest-like aggregation of hyphae during sexual development and serve as nurse cells to the developing cleistothecium, or fruiting body.


description: The process in which glycerol-2-phosphate is transported across a membrane. Glycerol-2-phosphate is a phosphoric monoester of glycerol.


hydrogen sulfide metabolic process

description: The chemical reactions and pathways involving hydrogen sulfide, H2S.


hydrogen sulfide biosynthetic process

description: The chemical reactions and pathways resulting in the formation of hydrogen sulfide, H2S.


peptidyl-lysine 5-dioxygenase activity

category: biolink:MolecularActivity biolink:Occurrent biolink:OntologyClass biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: Catalysis of the reaction: protein L-lysine + 2-oxoglutarate + O2 = protein 5-hydroxy-L-lysine + succinate + CO2.


name: P-TEFb-cap methyltransferase complex localization

description: Any process in which the P-TEFb-cap methyltransferase complex is transported to, or maintained in, a specific location.


protoporphyrinogen oxidase activity

description: Catalysis of the reaction: protoporphyrinogen IX + acceptor = protoporphyrin IX + reduced acceptor.


name: menaquinone-dependent protoporphyrinogen oxidase activity

description: Catalysis of the reaction: protoporphyrinogen IX + menaquinone = protoporphyrin IX + reduced menaquinone.


tertiary granule

category: biolink:CellularComponent biolink:AnatomicalEntity biolink:PhysicalEssence biolink:OrganismalEntity biolink:SubjectOfInvestigation biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: A secretory granule that contains cathepsin and gelatinase and is readily exocytosed upon cell activation; found primarily in mature neutrophil cells.


tertiary granule membrane

description: The lipid bilayer surrounding a tertiary granule.


Sin3-type complex

description: Any of a number of evolutionarily conserved histone deacetylase complexes (HDACs) containing a core consisting of a paired amphipathic helix motif protein (e.g. Sin3p in S. cerevisiae, Pst1 in S. pombe or Sin3A in mammals) at least one class I histone deacetylase (e.g. Rpd3p in S. cerevisiae, Clr6 in S. pombe, or HDAC1 and HDAC2 in mammals), and at least one WD40 repeat protein (e.g. Ume1p in S. cerevisiae, Prw1 in S. pombe, or RbAp46 and RbAp48 in mammals). These complexes also contain a variable number of other proteins that direct histone binding, DNA binding, or add other functionality to the complex.


HDA1 complex

description: A tetrameric histone deacetylase complex that contains a Class II deacetylase catalytic subunit. In S. cerevisiae it is composed of two Hda1p subunits along with Hda2p and Hda3p.


SHREC complex

description: A histone deacetylase complex that contains a core of four proteins -- Clr1, Clr2, Clr3, and Mit1 in fission yeast -- and localizes to all heterochromatic regions in the genome as well as some euchromatic sites. The complex is involved in regulating nucleosome positioning to assemble higher-order chromatin structures.


chrorion micropyle

description: A single cone-shaped specialization that forms an opening in the egg chorion that allows sperm entry into the egg prior to fertilization.


paraferritin complex

description: A cytoplasmic protein complex that contains integrin, mobilferrin and a flavin monooxygenase, is capable of reducing Fe(III) to Fe(II) utilizing NADPH, and is involved in iron transport. Fe(II) is required in the cell as the substrate for ferrochelatase in the synthesis of heme.


heterochromatin organization

description: Any process that results in the specification, formation or maintenance of the physical structure of eukaryotic heterochromatin, a compact and highly condensed form of chromatin.


bicellular tight junction assembly

description: The aggregation, arrangement and bonding together of a set of components to form a tight junction, an occluding cell-cell junction that is composed of a branching network of sealing strands that completely encircles the apical end of each cell in an epithelial sheet.


basement membrane assembly

description: The aggregation, arrangement and bonding together of a set of components to form a basement membrane, a part of the extracellular region that consists of a thin layer of dense material found in various animal tissues interposed between the cells and the adjacent connective tissue.


name: phosphatidylcholine biosynthesis from phosphoryl-ethanolamine via N-dimethylethanolamine phosphate and CDP-choline

description: The phosphatidylcholine biosynthetic process that begins with three consecutive N-methylation steps that are carried out on phospho-bases, phosphoethanolamine, phospho-N-methylethanolamine, and phospho-N-dimethylethanolamine; the process ends with the conversion of a phosphatidyl-N-dimethylethanolamine to a phosphatidylcholine.


name: phosphatidylcholine biosynthesis from phosphoryl-ethanolamine via CDP-N-methylethanolamine

description: The phosphatidylcholine biosynthetic process that begins with an initial N-methylation with phospho-base phosphoethanolamine, followed by two downstream N-methylations on phosphatidyl-bases, phosphatidyl-N-methylethanolamine and phosphatidyl-N-dimethylethanolamine. The process ends with the conversion of a phosphatidyl-N-dimethylethanolamine to a phosphatidylcholine.


name: phosphatidylcholine biosynthesis from phosphoryl-ethanolamine via N-dimethylethanolamine phosphate and CDP-N-dimethylethanolamine

description: The phosphatidylcholine biosynthetic process that begins with two N-methylations with phospho-base phosphoethanolamine and phospho-N-methylethanolamine, followed by a downstream N-methylation on phosphatidyl-base phosphatidyl-N-dimethylethanolamine; the process ends with the conversion of a phosphatidyl-N-dimethylethanolamine to a phosphatidylcholine.


name: chromium ion transmembrane transporter activity

description: Enables the transfer of chromium (Cr) ions from one side of a membrane to the other.


caveola assembly

description: The aggregation, arrangement and bonding together of a set of components to form a caveola. A caveola is a plasma membrane raft that forms a small pit, depression, or invagination that communicates with the outside of a cell and extends inward, indenting the cytoplasm and the cell membrane.


dehydroascorbic acid transport

description: The directed movement of dehydroascorbate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Dehydroascorbate, 5-(1,2-dihydroxyethyl)furan-2,3,4(5H)-trione, is an oxidized form of vitamin C.


dynein complex binding

description: Binding to a dynein complex, a protein complex that contains two or three dynein heavy chains and several light chains, and has microtubule motor activity.


inclusion body assembly

description: The aggregation, arrangement and bonding together of a set of components to form an inclusion body.


aggresome assembly

description: The aggregation, arrangement and bonding together of a set of components to form an aggresome; requires the microtubule cytoskeleton and dynein.


misfolded protein transport

description: The directed movement of misfolded proteins in a cell, including the movement of proteins between specific compartments or structures within a cell.


polyubiquitinated protein transport

description: The directed movement of polyubiquitinated proteins in a cell, including the movement of proteins between specific compartments or structures within a cell.


name: polyubiquitinated misfolded protein transport

description: The directed movement of misfolded polyubiquitinated proteins in a cell, including the movement of proteins between specific compartments or structures within a cell.


Hsp90 deacetylation

description: The modification of an Hsp90 protein by removal of acetyl groups.


core mediator complex

description: A protein complex that interacts with the carboxy-terminal domain of the largest subunit of RNA polymerase II and plays an active role in transducing the signal from a transcription factor to the transcriptional machinery. The core mediator complex has a stimulatory effect on basal transcription, and contains most of the same subdomains as the larger form of mediator complex -- a head domain comprising proteins known in Saccharomyces as Srb2, -4, and -5, Med6, -8, and -11, and Rox3 proteins; a middle domain comprising Med1, -4, and -7, Nut1 and -2, Cse2, Rgr1, Soh1, and Srb7 proteins; and a tail consisting of Gal11p, Med2p, Pgd1p, and Sin4p -- but lacks the regulatory subcomplex comprising Ssn2, -3, and -8, and Srb8 proteins. Metazoan core mediator complexes have similar modular structures and include homologs of yeast Srb and Med proteins.


response to growth factor

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth factor stimulus.


response to epidermal growth factor

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an epidermal growth factor stimulus.


TACC/TOG complex

description: A protein complex that contains the transforming acidic coiled coil (TACC) protein and the TOG protein (Mia1p/Alp7p and Alp14, respectively, in fission yeast), and is involved in microtubule array remodeling as cells progress through the cell cycle. The TACC/TOG complex is conserved in eukaryotes, associates with microtubules, and shuttles between the nucleus and the cytoplasm during interphase.


growth factor receptor binding

description: Binding to a growth factor receptor.


cell body fiber

description: A neuron projection that is found in unipolar neurons and corresponds to the region between the cell body and the point at which the single projection branches.


myosin VI binding

description: Binding to a class VI myosin. The myosin VI heavy chain has a single IQ motif in the neck and a tail region with a coiled coil domain followed by a unique globular domain, a unique insertion that enables myosin VI to move towards the pointed or minus end of actin filaments.


myosin VI heavy chain binding

description: Binding to a heavy chain of a myosin VI complex.


myosin VI head/neck binding

description: Binding to the head/neck region of a myosin VI heavy chain.


myosin VI light chain binding

description: Binding to a light chain of a myosin VI complex.


name: regulation of bile acid biosynthetic process

description: Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of bile acids.


name: negative regulation of bile acid biosynthetic process

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of bile acids.


name: positive regulation of bile acid biosynthetic process

description: Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of bile acids.


RNA polymerase I core factor complex

description: A RNA polymerase I-specific transcription factor complex that is required for the transcription of rDNA by RNA polymerase I. In yeast the complex consists of Rrn6p, Rrn7p, and Rrn11p.


name: regulation of protein exit from endoplasmic reticulum

description: Any process that modulates the frequency, rate or extent of the directed movement of proteins from the endoplasmic reticulum.


name: negative regulation of protein exit from endoplasmic reticulum

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of proteins from the endoplasmic reticulum.


name: positive regulation of protein exit from endoplasmic reticulum

description: Any process that activates or increases the frequency, rate or extent of directed movement of proteins from the endoplasmic reticulum.


sperm individualization complex

description: A cellular structure that includes cytoskeletal components and part of the cell membrane. Forms at the nuclear end of a male germline syncytium, or cyst, and translocates the over the length of the syncytium in the course of sperm individualization. Each complex contains an array of 64 investment cones, one per nucleus, that move synchronously along the spermatogenic cyst.


investment cone

description: A cytoskeletal part that consists of a microfilament-rich cone that forms round each nucleus in a spermatogenic cyst and translocates the length of the cyst during sperm individualization.


sterol-dependent protein binding

description: Binding to a protein or protein complex in the presence of sterols.


mating projection tip membrane

description: The portion of the plasma membrane surrounding a mating projection tip.


name: cell wall organization involved in conjugation with cellular fusion

description: A process of cell wall organization that contributes to conjugation with cellular fusion.


name: regulation of glycogen metabolic process

description: Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving glycogen.


name: negative regulation of glycogen metabolic process

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving glycogen.


name: positive regulation of glycogen metabolic process

description: Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving glycogen.


SOSS complex

description: A protein complex that functions downstream of the MRN complex to promote DNA repair and the G2/M checkpoint. The SOSS complex associates with single-stranded DNA at DNA lesions and is composed of SOSS-B (SOSS-B1/OBFC2B or SOSS-B2/OBFC2A), SOSS-A/INTS3 and SOSS-C/C9orf80.


microprocessor complex

description: A protein complex that binds to heme and to pri-miRNAs, and is required for the formation of a pre-microRNA (pre-miRNA), the initial step of microRNA (miRNA) biogenesis. The complex is composed of the double-stranded-RNA-specific RNase Drosha (also called RNASEN) and the RNA-binding protein DGCR8 (heme-free or heme-bound forms). Within the complex, DGCR8 function as a molecular anchor necessary for the recognition of pri-miRNA at dsRNA-ssRNA junction and directs RNASEN/Drosha to cleave the 3' and 5' strands of a stem-loop to release hairpin-shaped pre-miRNAs.


primary miRNA binding

description: Binding to a primary microRNA (pri-miRNA) transcript, an RNA molecule that is processed into a short hairpin-shaped structure called a pre-miRNA and finally into a functional miRNA. Both double-stranded and single-stranded regions of a pri-miRNA are required for binding.


name: fungal-type cell wall beta-glucan metabolic process

description: The chemical reactions and pathways involving beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of fungal cells.


name: fungal-type cell wall beta-glucan biosynthetic process

description: The chemical reactions and pathways resulting in the formation of beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of fungal cells.


regulation of proline transport

description: Any process that modulates the frequency, rate or extent of proline transport.


pre-miRNA binding

description: Binding to a precursor microRNA (pre-miRNA) transcript, a stem-loop-containing precursor of microRNA.


name: regulation of calcineurin-NFAT signaling cascade

description: Any process that modulates the frequency, rate or extent of the calcineurin-NFAT signaling cascade.


name: negative regulation of calcineurin-NFAT signaling cascade

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the calcineurin-NFAT signaling cascade.


name: positive regulation of calcineurin-NFAT signaling cascade

description: Any process that activates or increases the frequency, rate or extent of signaling via the calcineurin-NFAT signaling cascade.


cellular response to chemical stimulus

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus.


E-box binding

description: Binding to an E-box, a DNA motif with the consensus sequence CANNTG that is found in the promoters of a wide array of genes expressed in neurons, muscle and other tissues.


platelet alpha granule organization

description: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a platelet alpha granule. A platelet alpha granule is a secretory organelle found in blood platelets.


lipoteichoic acid binding

description: Binding to lipoteichoic acid.


name: lipoteichoic acid immune receptor activity

description: Combining with lipoteichoic acid and transmitting the signal to initiate an innate immune response.


name: transcription preinitiation complex assembly

description: The formation of a large multiprotein-DNA complex that self-assembles on gene promoter through the sequential recruitment of the general initiation factors that compose the preinitiation complex (PIC). The PIC engages the RNA polymerase on its DNA template strand and sparks polymerization of the first few RNA nucleotides.


name: RNA polymerase III preinitiation complex assembly

description: The formation of a large multiprotein-DNA complex that self-assembles on a tRNA gene through the sequential recruitment of the general initiation factors that compose the preinitiation complex (PIC), (which includes BDP1, BRF1, TBP, TFIIIC in human). The PIC engages RNA polymerase III on its DNA template strand and sparks polymerization of the first few RNA nucleotides.


name: mitochondrial tRNA wobble uridine modification

description: The process in which a uridine in position 34 of a mitochondrial tRNA is post-transcriptionally modified.


mitochondrial tRNA modification

description: The covalent alteration of one or more nucleotides within a mitochondrial tRNA molecule to produce a mitochondrial tRNA molecule with a sequence that differs from that coded genetically.


mitochondrial tRNA methylation

description: The posttranscriptional addition of methyl groups to specific residues in a mitochondrial tRNA molecule.


name: mitochondrial tRNA pseudouridine synthesis

description: The intramolecular conversion of uridine to pseudouridine in a mitochondrial tRNA molecule.


mitochondrial tRNA thio-modification

description: The addition a sulfur atom to a nucleotide in a mitochondrial tRNA molecule.


serine binding

description: Binding to 2-amino-3-hydroxypropanoic acid.


name: aspartate:alanine antiporter activity

description: Catalysis of the reaction: aspartate(out) + alanine(in) = aspartate(in) + alanine(out).


description: Catalysis of the reaction: L-histidine(out) + histamine(in) = L-histidine(in) + histamine(out).


name: tyrosine:tyramine antiporter activity

description: Catalysis of the reaction: tyrosine(out) + tyramine(in) = tyrosine(in) + tyramine(out).


name: glutamate:gamma-aminobutyric acid antiporter activity

description: Catalysis of the reaction: glutamate(out) + gamma-aminobutyric acid(in) = glutamate(in) + gamma-aminobutyric acid(out).


name: cell wall macromolecule catabolic process involved in cell wall disassembly

description: The chemical reactions and pathways that result in the breakdown of macromolecules that form part of a cell wall, and contributes to the breakdown of the cell wall.


name: global genome nucleotide-excision repair

description: The nucleotide-excision repair process in which DNA lesions are removed from nontranscribed strands and from transcriptionally silent regions over the entire genome.


Ddb1-Ckn1 complex

description: A heterodimeric nucleotide-excision repair complex that is involved in transcription-coupled repair. The subunits are known as Ddb1 and Ckn1 in S. pombe; Ddb1 contains a motif called the DDB-box that interacts with adaptor proteins for DDB1/cullin 4 ubiquitin ligases.


Ddb1-Wdr21 complex

description: A heterodimeric nucleotide-excision repair complex that is involved in transcription-coupled repair. The subunits are known as Ddb1 and Wdr21 in S. pombe; Ddb1 contains a motif called the DDB-box that interacts with adaptor proteins for DDB1/cullin 4 ubiquitin ligases.


UV-damage excision repair

description: A DNA repair process that is initiated by an endonuclease that introduces a single-strand incision immediately 5' of a UV-induced damage site. UV-damage excision repair acts on both cyclobutane pyrimidine dimers (CPDs) and pyrimidine-pyrimidone 6-4 photoproducts (6-4PPs).


lysophosphatidic acid receptor activity

description: Combining with the phospholipid derivative lysophosphatidic acid, and transmitting the signal across the membrane by activating an associated G-protein.


name: inositol phosphoceramide synthase complex

description: A protein complex that possesses inositol phosphoceramide synthase activity and contains a catalytic subunit and a regulatory subunit (Aur1p and Kei1p, respectively, in Saccharomyces).


name: inositol phosphoceramide synthase regulator activity

description: Binds to and modulates the activity of inositol phosphoceramide synthase.


regulatory ncRNA processing

description: A process leading to the generation of a functional regulatory non-coding RNA.


name: regulation of regulatory ncRNA processing

description: Any process that modulates the frequency, rate or extent of regulatory non-coding RNA processing.


regulation of siRNA processing

description: Any process that modulates the frequency, rate or extent of siRNA processing.


RISC complex assembly

description: The process in which a single-stranded small RNA is incorporated within the RNA-initiated silencing complex (RISC). The assembly includes the maturation of the small RNA, the stabilization of the complex by accessory proteins of the RISC complex, duplex separation and the release of the second strand, forming a base-pairing complement complex that mediates gene silencing by small RNA.


organelle assembly

description: The aggregation, arrangement and bonding together of a set of components to form an organelle. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.


name: regulation of ATP:ADP antiporter activity

description: Any process that modulates the activity of an ATP:ADP antiporter.


name: negative regulation of ATP:ADP antiporter activity

description: Any process that stops or reduces the activity of an ATP:ADP antiporter.


trans-translation

description: A translational elongation process in which transfer of a translating ribosome from one mRNA to another RNA template takes place. Trans-translation occurs during tmRNA release of stalled ribosomes.


description: A protein modification process in which a polypeptide is added to a nascent polypeptide cotranslationally by trans-translation.


Golgi-associated vesicle lumen

description: The volume enclosed by the membrane of a Golgi-associated vesicle.


CRD-mediated mRNA stabilization

description: An mRNA stabilization process in which one or more RNA-binding proteins associate with a sequence in the open reading frame called the coding region instability determinant (CRD).


3'-UTR-mediated mRNA stabilization

description: An mRNA stabilization process in which one or more RNA-binding proteins associate with the 3'-untranslated region (UTR) of an mRNA.


protein K48-linked ubiquitination

description: A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 48 of the ubiquitin monomers, is added to a protein. K48-linked ubiquitination targets the substrate protein for degradation.


CRD-mediated mRNA stability complex

description: A protein complex that binds to, and promotes stabilization of, mRNA molecules containing the coding region instability determinant (CRD). In human, it may consist of IGF2BP1, HNRNPU, SYNCRIP/HNRNPQ, YBX1, and DHX9.


contractile ring

description: A cytoskeletal structure composed of filamentous protein that forms beneath the membrane of many cells or organelles, in the plane of cell or organelle division. Ring contraction is associated with centripetal growth of the membrane that divides the cytoplasm of the two daughter cells or organelles.


Dsl1/NZR complex

description: A multisubunit tethering complex, i.e. a protein complex involved in mediating the initial interaction between vesicles and the membranes with which they fuse, that is involved in trafficking from the Golgi apparatus to the ER. In Saccharomyces cerevisiae the Dsl1p complex contains Dsl1p, Tip20p, and Sec39p.


eisosome assembly

description: The aggregation, arrangement and bonding together of a set of components to form an eisosome, a cell part that is composed of the eisosome membrane and eisosome filaments. The eisosome membrane, also called the MCC domain, is a furrow-like plasma membrane sub-domain with associated integral transmembrane proteins. The eisosome filaments form a scaffolding lattice on the cytoplasmic face of the membrane.


neutrophil mediated cytotoxicity

description: The directed killing of a target cell by a neutrophil.


name: neutrophil-mediated killing of symbiont cell

description: The directed killing of a symbiont target cell by a neutrophil. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.


name: neutrophil-mediated killing of bacterium

description: The directed killing of a bacterium by a neutrophil.


name: neutrophil-mediated killing of gram-negative bacterium

description: The directed killing of a gram-negative bacterium by a neutrophil.


name: neutrophil-mediated killing of gram-positive bacterium

description: The directed killing of a gram-positive bacterium by a neutrophil.


neutrophil-mediated killing of fungus

description: The directed killing of a fungal cell by a neutrophil.


name: regulation of neutrophil mediated cytotoxicity

description: Any process that modulates the rate, frequency or extent of neutrophil mediated killing of a target cell, the directed killing of a target cell by a neutrophil.


name: regulation of neutrophil mediated killing of symbiont cell

description: Any process that modulates the rate, frequency or extent of neutrophil mediated killing of a symbiont cell, the directed killing of a symbiont target cell by a neutrophil.


name: regulation of neutrophil mediated killing of bacterium

description: Any process that modulates the rate, frequency or extent of neutrophil mediated killing of a bacterium, the directed killing of a bacterium by a neutrophil.


name: regulation of neutrophil mediated killing of gram-negative bacterium

description: Any process that modulates the rate, frequency or extent of neutrophil mediated killing of a gram-negative bacterium, the directed killing of a gram-negative bacterium by a neutrophil.


name: regulation of neutrophil mediated killing of gram-positive bacterium

description: Any process that modulates the rate, frequency or extent of neutrophil mediated killing of a gram-positive bacterium, the directed killing of a gram-positive bacterium by a neutrophil.


name: regulation of neutrophil mediated killing of fungus

description: Any process that modulates the rate, frequency or extent of neutrophil mediated killing of a fungal cell, the directed killing of a fungal cell by a neutrophil.


name: negative regulation of neutrophil mediated cytotoxicity

description: Any process that decreases the frequency, rate or extent of the directed killing of a target cell by a neutrophil.


name: negative regulation of neutrophil mediated killing of symbiont cell

description: Any process that decreases the frequency, rate or extent of the directed killing of a symbiont target cell by a neutrophil.


name: negative regulation of neutrophil mediated killing of bacterium

description: Any process that decreases the frequency, rate or extent of the directed killing of a bacterium by a neutrophil.


name: negative regulation of neutrophil mediated killing of gram-negative bacterium

description: Any process that decreases the frequency, rate or extent of the directed killing of a gram-negative bacterium by a neutrophil.


name: negative regulation of neutrophil mediated killing of gram-positive bacterium

description: Any process that decreases the frequency, rate or extent of the directed killing of a gram-positive bacterium by a neutrophil.


name: negative regulation of neutrophil mediated killing of fungus

description: Any process that decreases the frequency, rate or extent of the directed killing of a fungal cell by a neutrophil.


name: positive regulation of neutrophil mediated cytotoxicity

description: Any process that increases the frequency, rate or extent of the directed killing of a target cell by a neutrophil.


name: positive regulation of neutrophil mediated killing of symbiont cell

description: Any process that increases the frequency, rate or extent of the directed killing of a symbiont target cell by a neutrophil.


name: positive regulation of neutrophil mediated killing of bacterium

description: Any process that increases the frequency, rate or extent of the directed killing of a bacterium by a neutrophil.


name: positive regulation of neutrophil mediated killing of gram-negative bacterium

description: Any process that increases the frequency, rate or extent of the directed killing of a gram-negative bacterium by a neutrophil.


name: positive regulation of neutrophil mediated killing of gram-positive bacterium

description: Any process that increases the frequency, rate or extent of the directed killing of a gram-positive bacterium by a neutrophil.


name: positive regulation of neutrophil mediated killing of fungus

description: Any process that increases the frequency, rate or extent of the directed killing of a fungal cell by a neutrophil.


name: nuclear-transcribed mRNA catabolic process, no-go decay

description: The chemical reactions and pathways resulting in the breakdown of the transcript body of a nuclear-transcribed mRNA with stalls in translation elongation.


coenzyme F420 binding

description: Binding to F420, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes.


pyrroloquinoline quinone binding

description: Binding to pyrroloquinoline quinone, PQQ, the coenzyme or the prosthetic group of certain alcohol dehydrogenases and glucose dehydrogenases.


endoplasmic reticulum exit site

description: An endoplasmic reticulum part at which COPII-coated vesicles are produced.


name: protein localization to endoplasmic reticulum

description: A process in which a protein is transported to, or maintained in, a location within the endoplasmic reticulum.


name: protein localization to endoplasmic reticulum exit site

description: A process in which a protein is transported to, or maintained in, a location at an endoplasmic reticulum exit site.


POU domain binding

description: Binding to a POU domain of a protein. The POU domain is a bipartite DNA binding domain composed of two subunits separated by a non-conserved region of 15-55 amino acids; it is found in several eukaryotic transcription factors.


FHA domain binding

description: Binding to a FHA domain of a protein. The FHA domain is a phosphopeptide recognition domain found in many regulatory proteins, and consists of approximately 80-100 amino acid residues folded into an 11-stranded beta sandwich.


TIR domain binding

description: Binding to a Toll-Interleukin receptor (TIR) domain of a protein. The TIR domain is an intracellular 200 residue domain that is found in the Toll protein, the interleukin-1 receptor (IL-1R), and MyD88; it contains three highly-conserved regions, and mediates protein-protein interactions between the Toll-like receptors (TLRs) and signal-transduction components.


bone maturation

description: A developmental process, independent of morphogenetic (shape) change, that is required for bone to attain its fully functional state.


name: voltage-gated calcium channel complex assembly

description: Cellular protein complex assembly that results in the formation of a voltage-gated calcium channel complex.


protein K11-linked ubiquitination

description: A protein ubiquitination process in which ubiquitin monomers are attached to a protein, and then ubiquitin polymers are formed by linkages between lysine residues at position 11 of the ubiquitin monomers. K11-linked polyubiquitination targets the substrate protein for degradation. The anaphase-promoting complex promotes the degradation of mitotic regulators by assembling K11-linked polyubiquitin chains.


biphenyl catabolic process

description: The chemical reactions and pathways resulting in the breakdown of biphenyl, a toxic aromatic hydrocarbon used as a heat transfer agent, as a fungistat in packaging citrus fruits and in plant disease control. Biphenyl can be chlorinated with 1-10 chlorine molecules to form polychlorinated biphenyls (PCBs).


L-asparagine biosynthetic process

description: The chemical reactions and pathways resulting in the formation of asparagine, (2S)-2-amino-3-carbamoylpropanoic acid.


L-asparagine metabolic process

description: The chemical reactions and pathways involving L-asparagine, (2S)-2-amino-3-carbamoylpropanoic acid.


dendrite guidance

description: The process in which the migration of a dendrite is directed to a specific target site in response to a combination of attractive and repulsive cues.


SET domain binding

description: Binding to a SET domain of a protein. SET domains are named after three Drosophila proteins that contain this domain: Su(var), E(z) and trithorax. SET domains are associated with histone lysine methylation.


transcription factor TFIIK complex

description: A transcription factor complex that forms part of the holo TFIIH complex. In Saccharomyces/human, TFIIK contains Ccl1p/Cyclin H, Tfb3p/MAT1 and Kin28p/CDK7.


left/right axis specification

description: The establishment, maintenance and elaboration of the left/right axis. The left/right axis is defined by a line that runs orthogonal to both the anterior/posterior and dorsal/ventral axes. Each side is defined from the viewpoint of the organism rather of the observer (as per anatomical axes).


error-free translesion synthesis

description: The conversion of DNA-damage induced single-stranded gaps into large molecular weight DNA after replication by using a specialized DNA polymerase or replication complex to insert a defined nucleotide across the lesion. This process does not remove the replication-blocking lesions but does not causes an increase in the endogenous mutation level. For S. cerevisiae, RAD30 encodes DNA polymerase eta, which incorporates two adenines. When incorporated across a thymine-thymine dimer, it does not increase the endogenous mutation level.


demethylation

description: The process of removing one or more methyl groups from a molecule.


oxidative demethylation

description: The process of removing one or more methyl groups from a molecule, involving the oxidation (i.e. electron loss) of one or more atoms in the substrate.


snRNP binding

description: Binding to a small nuclear ribonucleoprotein particle.


name: medium-chain fatty acyl-CoA dehydrogenase activity

description: Catalysis of the reaction: a medium-chain 2,3-saturated fatty acyl-CoA + H+ + oxidized [electron-transfer flavoprotein] = a medium-chain trans-(2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]. A medium-chain fatty acid has an aliphatic tail containing 6 to 12 carbons.


translation initiation complex

description: A ribonucleoprotein complex that contains a ribosome, mRNA, and initiator tRNA; the functional ribosome is at the AUG, with the methionyl/formyl-methionyl-tRNA positioned at the P site.


translation preinitiation complex

description: A ribonucleoprotein complex that contains the small ribosomal subunit, a translation initiation ternary complex (i.e. an initiator tRNA, GTP, and an IF2 or eIF2 complex), and an mRNA.


detection of oxidative stress

description: The series of events in which a stimulus indicating oxidative stress is received and converted into a molecular signal.


NADPH oxidation

description: A metabolic process that results in the oxidation of reduced nicotinamide adenine dinucleotide, NADPH, to the oxidized form, NADP.


type 1 melanocortin receptor binding

description: Binding to a type 1 melanocortin receptor.


sensory perception of gravity

description: The series of events required for an organism to receive a gravitational stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.


name: detection of mechanical stimulus involved in sensory perception of gravity

description: The series of events involved in the perception of gravity in which a sensory mechanical stimulus is received and converted into a molecular signal.


response to magnetism

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a magnetic stimulus.


U4/U6 snRNP

description: A ribonucleoprotein complex that contains the extensively base paired small nuclear RNAs U4 and U6, a heptameric ring of Sm proteins associated with U4, the Lsm2-8 heptameric ring complex associated with U6, as well as several proteins that are unique to the U4 snRNP or U6 snRNPs, some of which remain associated with the U4/U6 snRNA both while the U4 snRNP is free or assembled into a series of spliceosomal complexes.


U4atac/U6atac snRNP

description: A ribonucleoprotein complex that contains the extensively base paired small nuclear RNAs U4atac and U6atac, a heptameric ring of Sm proteins associated with U4atac, the Lsm2-8 heptameric ring complex associated with U6atac, as well as several proteins that are unique to the U4atac snRNP or U6atac snRNPs, some of which remain associated with the U4atac/U6atac snRNA both while the U4atac snRNP is free or assembled into a series of spliceosomal complexes.


penta-snRNP complex

description: A ribonucleoprotein complex that is formed by the association of the U1, U2, U4/U6 and U5 small nuclear ribonucleoproteins.


U2-type prespliceosome

description: A spliceosomal complex that is formed by association of the 5' splice site with the U1 snRNP, while the branch point sequence is recognized by the U2 snRNP. The prespliceosome includes many proteins in addition to those found in the U1 and U2 snRNPs. Commitment to a given pair of 5' and 3' splice sites occurs at the time of prespliceosome formation.


U2-type precatalytic spliceosome

description: A spliceosomal complex that is formed by the recruitment of the preassembled U4/U6.U5 tri-snRNP to the prespliceosome. Although all 5 snRNPs are present, the precatalytic spliceosome is catalytically inactive. The precatalytic spliceosome includes many proteins in addition to those found in the U1, U2 and U4/U6.U5 snRNPs.


U2-type catalytic step 1 spliceosome

description: A spliceosomal complex that is formed by the displacement of the U1 and U4 snRNPs from the precatalytic spliceosome; the U2, U5 and U6 snRNPs remain associated with the mRNA. This complex, sometimes called the activated spliceosome, is the catalytically active form of the spliceosome, and includes many proteins in addition to those found in the U2, and U5 and U6 snRNPs.


U2-type catalytic step 2 spliceosome

description: A spliceosomal complex that contains the U2, U5 and U6 snRNPs bound to a splicing intermediate in which the first catalytic cleavage of the 5' splice site has occurred. The precise subunit composition differs significantly from that of the catalytic step 1, or activated, spliceosome, and includes many proteins in addition to those found in the U2, U5 and U6 snRNPs.


name: U2-type post-mRNA release spliceosomal complex

description: A spliceosomal complex that is formed following the release of the spliced product from the post-spliceosomal complex and contains the excised intron and the U2, U5 and U6 snRNPs.


U4atac/U6atac x U5 tri-snRNP complex

description: A spliceosomal snRNP complex that is formed by the association of the U4atac/U6atac and U5 snRNPs.


prespliceosome

description: A spliceosomal complex that is formed by association of the 5' splice site and the branch point sequence with specific snRNPs. The prespliceosome includes many proteins in addition to those found in the bound snRNPs. Commitment to a given pair of 5' and 3' splice sites occurs at the time of prespliceosome formation. Prespliceosome complexes are not active for splicing, but are instead an early step in the assembly of a spliceosomal complex.


precatalytic spliceosome

description: A spliceosomal complex that is formed by the recruitment of a preassembled U5-containing tri-snRNP to the prespliceosome. Although all 5 snRNPs are present, the precatalytic spliceosome is catalytically inactive. The precatalytic spliceosome includes many proteins in addition to those found in the associated snRNPs.


catalytic step 1 spliceosome

description: A spliceosomal complex that is formed by the displacement of the two snRNPs from the precatalytic spliceosome; three snRNPs including U5 remain associated with the mRNA. This complex, sometimes called the activated spliceosome, is the catalytically active form of the spliceosome, and includes many proteins in addition to those found in the associated snRNPs.


catalytic step 2 spliceosome

description: A spliceosomal complex that contains three snRNPs, including U5, bound to a splicing intermediate in which the first catalytic cleavage of the 5' splice site has occurred. The precise subunit composition differs significantly from that of the catalytic step 1, or activated, spliceosome, and includes many proteins in addition to those found in the associated snRNPs.


post-mRNA release spliceosomal complex

description: A spliceosomal complex that is formed following the release of the spliced product from the post-spliceosomal complex and contains the excised intron and three snRNPs, either U2 or U12, U5, and either U6 or U6atac.


U12-type prespliceosome

description: A spliceosomal complex that is formed by the cooperative binding of the heterodimeric U11/U12 snRNP to the 5' splice site and the branch point sequence. The U12-type prespliceosome includes many proteins in addition to those found in the U11/U12 heterodimeric snRNPs. Commitment to a given pair of 5' and 3' splice sites occurs at the time of prespliceosome formation.


U12-type precatalytic spliceosome

description: A spliceosomal complex that is formed by the recruitment of the preassembled U4atac/U6atac.U5 tri-snRNP to the U12-type prespliceosome. Although all 5 snRNPs are present, the precatalytic spliceosome is catalytically inactive. The precatalytic spliceosome includes many proteins in addition to those found in the U11, U12 and U4atac/U6atac.U5 snRNPs.


U12-type catalytic step 1 spliceosome

description: A spliceosomal complex that is formed by the displacement of the U11 and U4atac snRNPs from the precatalytic spliceosome; the U12, U5 and U6atac snRNPs remain associated with the mRNA. This complex, sometimes called the activated spliceosome, is the catalytically active form of the spliceosome, and includes many proteins in addition to those found in the U12, and U5 and U6atac snRNPs.


U12-type catalytic step 2 spliceosome

description: A spliceosomal complex that contains the U12, U5 and U6atac snRNPs bound to a splicing intermediate in which the first catalytic cleavage of the 5' splice site has occurred. The precise subunit composition differs significantly from that of the catalytic step 1, or activated, spliceosome, and includes many proteins in addition to those found in the U12, U5 and U6atac snRNPs.


name: U12-type post-mRNA release spliceosomal complex

description: A spliceosomal complex that is formed following the release of the spliced product from the post-spliceosomal complex and contains the excised intron and the U12, U5 and U6atac snRNPs.


post-spliceosomal complex

description: A spliceosomal complex that is formed following the second splicing event and contains the spliced product, the excised intron, and three snRNPs, including U5.


U2-type post-spliceosomal complex

description: A spliceosomal complex that is formed following the second splicing event and contains the spliced product, the excised intron, and three snRNPs, U5, U2 and U6.


U12-type post-spliceosomal complex

description: A spliceosomal complex that is formed following the second splicing event and contains the spliced product, the excised intron, and three snRNPs, U5, U12 and U6atac.


trans spliceosomal complex

description: A spliceosomal complex that forms during the addition of a specific spliced leader (SL) sequence to the 5'-end of a messenger RNA primary transcript, a process which occurs in a number of eukaryotic organisms, including trypanosomatid protozoans, euglenoids, nematodes, trematodes, and chordates.


SL snRNP

description: A ribonucleoprotein complex that contains spliced leader (SL) RNA and associated proteins.


RNA surveillance

description: A process that identifies and degrades defective or aberrant RNAs.


cytoplasmic RNA surveillance

description: The set of processes involved in identifying and degrading defective or aberrant RNAs within the cytoplasm.


nuclear RNA surveillance

description: A process that identifies and degrades defective or aberrant RNAs within the nucleus.


nuclear mRNA surveillance

description: A process that identifies and degrades defective or aberrant mRNAs within the nucleus.


name: nuclear mRNA surveillance of spliceosomal pre-mRNA splicing

description: The set of processes involved in identifying and degrading incorrectly spliced pre-mRNAs within the nucleus.


name: nuclear mRNA surveillance of mRNA 3'-end processing

description: The set of processes involved in identifying and degrading mRNAs with incorrectly formed 3'-ends within the nucleus.


name: nuclear mRNA surveillance of mRNP export

description: The set of processes involved in identifying and degrading incorrectly formed or aberrant nuclear mRNPs docked at the nuclear pore complex prior to export to the cytoplasm.


CUT catabolic process

description: The chemical reactions and pathways resulting in the breakdown of cryptic unstable transcripts (CUTs).


name: nuclear polyadenylation-dependent rRNA catabolic process

description: The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of a ribosomal RNA (rRNA) molecule, including RNA fragments released as part of processing the primary transcript into multiple mature rRNA species, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target rRNA.


name: nuclear polyadenylation-dependent snoRNA catabolic process

description: The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of a small nucleolar RNA (snoRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target snoRNA.


name: nuclear polyadenylation-dependent snRNA catabolic process

description: The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of a small nuclear RNA (snRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target snRNA.


name: TRAMP-dependent tRNA surveillance pathway

description: A nuclear tRNA surveillance pathway, dependent on the TRAMP exosome adaptor and the nuclear exosome.


name: nuclear polyadenylation-dependent CUT catabolic process

description: The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of a cryptic unstable transcript (CUT), initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target CUT.


name: nuclear polyadenylation-dependent antisense transcript catabolic process

description: The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of an antisense transcript, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target antisense transcript.


name: antisense RNA transcript catabolic process

description: The chemical reactions and pathways resulting in the breakdown of antisense transcripts, i.e. transcripts that were produced from the antisense strand of a gene that produces a gene product and which often have a regulatory effect on the transcription of that gene product.


name: nuclear polyadenylation-dependent mRNA catabolic process

description: The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of a messenger RNA (mRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target mRNA.


CUT metabolic process

description: The chemical reactions and pathways involving cryptic unstable transcripts (CUTs), which are transcribed from intergenic regions. Many intergenic regions are heavily transcribed, but the transcripts are rarely detected due to rapid degradation by the nuclear exosome.


histone mRNA catabolic process

description: The chemical reactions and pathways resulting in the breakdown of histone messenger RNA (mRNA).


nuclear histone mRNA catabolic process

description: The chemical reactions and pathways resulting in the breakdown of histone messenger RNA (mRNA) within the nucleus.


name: nuclear polyadenylation-dependent ncRNA catabolic process

description: The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of a noncoding RNA (ncRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target ncRNA.


name: polyadenylation-dependent mRNA catabolic process

description: The chemical reactions and pathways resulting in the breakdown of a messenger RNA (mRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target mRNA.


name: poly(A)-dependent snoRNA 3'-end processing

description: Any process involved in forming the mature 3' end of a snoRNA molecule linked to prior polyadenylation of the 3'-end of the precursor snoRNA.


alpha9-beta1 integrin-ADAM1 complex

description: A protein complex that consists of an alpha9-beta1 integrin complex bound to the transmembrane metallopeptidase ADAM1.


alpha9-beta1 integrin-ADAM2 complex

description: A protein complex that consists of an alpha9-beta1 integrin complex bound to the transmembrane metallopeptidase ADAM2.


alpha9-beta1 integrin-ADAM3 complex

description: A protein complex that consists of an alpha9-beta1 integrin complex bound to the transmembrane metallopeptidase ADAM3.


alpha9-beta1 integrin-ADAM9 complex

description: A protein complex that consists of an alpha9-beta1 integrin complex bound to the transmembrane metallopeptidase ADAM9.


alpha9-beta1 integrin-ADAM15 complex

description: A protein complex that consists of an alpha9-beta1 integrin complex bound to the transmembrane metallopeptidase ADAM15.


alphav-beta3 integrin-ADAM15 complex

description: A protein complex that consists of an alphav-beta3 integrin complex bound to the transmembrane metallopeptidase ADAM15.


alpha3-beta1 integrin-CD151 complex

description: A protein complex that consists of an alpha3-beta1 integrin complex bound to the tetraspanin CD151.


alpha6-beta1 integrin-CD151 complex

description: A protein complex that consists of an alpha6-beta1 integrin complex bound to the tetraspanin CD151.


alpha7-beta1 integrin-CD151 complex

description: A protein complex that consists of an alpha7-beta1 integrin complex bound to the tetraspanin CD151.


alpha6-beta4 integrin-CD151 complex

description: A protein complex that consists of an alpha6-beta4 integrin complex bound to the tetraspanin CD151.


description: A protein complex that consists of an alphav-beta3 integrin complex bound to vitronectin.


sensory perception of wind

description: The series of events required for an organism to receive sensory mechanical stimulus resulting from air flow, convert it to a molecular signal, and recognize and characterize the signal.


description: A protein complex that consists of an alphaE-beta7 integrin complex bound to E-cadherin.


name: alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex

description: A protein complex that consists of an alpha9-beta1 integrin complex bound to vascular cell adhesion molecule-1.


name: detection of mechanical stimulus involved in sensory perception of wind

description: The series of events involved in the perception of wind in which a mechanical stimulus is received and converted into a molecular signal.


alphav-beta3 integrin-ADAM23 complex

description: A protein complex that consists of an alphav-beta3 integrin complex bound to the transmembrane metallopeptidase ADAM23.


alpha9-beta1 integrin-ADAM12 complex

description: A protein complex that consists of an alpha9-beta1 integrin complex bound to the transmembrane metallopeptidase ADAM12.


description: A protein complex that consists of an alpha4-beta1 integrin complex bound to thrombospondin-1.


description: A protein complex that consists of an alpha4-beta1 integrin complex bound to thrombospondin-2.


name: regulation of phospholipid biosynthetic process

description: Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phospholipids.


name: negative regulation of phospholipid biosynthetic process

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phospholipids.


name: positive regulation of phospholipid biosynthetic process

description: Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phospholipids.


name: eukaryotic initiation factor eIF2 binding

description: Binding to eukaryotic initiation factor eIF2, a protein complex involved in the initiation of ribosome-mediated translation.


CUGBP1-eIF2 complex

description: A protein complex that contains the eukaryotic translation initiation factor 2 complex (EIF2), CUG binding protein 1, and several endoplasmic reticulum proteins; the complex is involved in the regulation of translation.


RNA 3' uridylation

description: The enzymatic addition of a sequence of uridylyl residues at the 3' end of an RNA molecule.


name: adenosine 3',5'-bisphosphate transmembrane transporter activity

description: Enables the transfer of adenosine 3',5'-bisphosphate from one side of a membrane to the other.


description: A protein complex that consists of fibronectin bound to tissue transglutaminase, and is involved in cell adhesion.


description: A protein complex that consists of an alpha2-beta1 integrin complex bound to the cartilage matrix protein chondroadherin.


alpha3-beta1 integrin-basigin complex

description: A protein complex that consists of an alpha3-beta1 integrin complex bound to the cell surface protein basigin.


alpha3-beta1 integrin-CD63 complex

description: A protein complex that consists of an alpha3-beta1 integrin complex bound to the tetraspanin CD63.


alpha9-beta1 integrin-tenascin complex

description: A protein complex that consists of an alpha9-beta1 integrin complex bound to the extracellular matrix protein tenascin.


description: A protein complex that consists of an alphaV-beta3 integrin complex bound to the cell surface protein CD47 and the low-affinity immunoglobulin epsilon Fc receptor (FCER2).


alpha2-beta1 integrin-CD47 complex

description: A protein complex that consists of an alpha2-beta1 integrin complex bound to the cell surface protein CD47.


alphaIIb-beta3 integrin-CD9 complex

description: A protein complex that consists of an alphaIIb-beta3 integrin complex bound to the cell surface protein CD9.


name: alphaIIb-beta3 integrin-CD9-CD47-platelet glycoprotein Ib complex

description: A protein complex that consists of an alphaIIb-beta3 integrin complex bound to the cell surface proteins CD9 and CD47, and the heterodimeric platelet glycoprotein Ib.


name: alpha11-beta1 integrin-collagen type I complex

description: A protein complex that consists of an alpha11-beta1 integrin complex bound to a type I collagen.


name: alpha5-beta1 integrin-tissue transglutaminase complex

description: A protein complex that consists of an alpha5-beta1 integrin complex bound to tissue transglutaminase.


name: alphaV-beta3 integrin-tissue transglutaminase complex

description: A protein complex that consists of an alphaV-beta3 integrin complex bound to tissue transglutaminase.


name: alphaIIb-beta3 integrin-fibronectin-tissue transglutaminase complex

description: A protein complex that consists of an alphaIIb-beta3 integrin complex bound to fibronectin and tissue transglutaminase.


name: alpha1-beta1 integrin-tissue transglutaminase complex

description: A protein complex that consists of an alpha1-beta1 integrin complex bound to tissue transglutaminase.


name: alpha3-beta1 integrin-tissue transglutaminase complex

description: A protein complex that consists of an alpha3-beta1 integrin complex bound to tissue transglutaminase.


name: alpha5-beta1 integrin-fibronectin-tissue transglutaminase complex

description: A protein complex that consists of an alpha5-beta1 integrin complex bound to fibronectin and tissue transglutaminase.


alpha6-beta4 integrin-CD9 complex

description: A protein complex that consists of an alpha6-beta4 integrin complex bound to the cell surface protein CD9.


description: A protein complex that consists of an alpha3-beta1 integrin complex bound to thrombospondin.


alphaV-beta3 integrin-gelsolin complex

description: A protein complex that consists of an alphaV-beta3 integrin complex bound to gelsolin.


description: A protein complex that consists of an alphaV-beta3 integrin complex bound to paxillin and the FAK-related kinase Pyk2.


alpha6-beta4 integrin-Fyn complex

description: A protein complex that consists of an alpha6-beta4 integrin complex bound to the Src family tyrosine kinase Fyn.


alphaV-beta6 integrin-TGFbeta-3 complex

description: A protein complex that consists of an alphaV-beta6 integrin complex bound to transforming growth factor beta-3 (TGFbeta-3).


description: A protein complex that consists of an alphaV-beta8 integrin complex bound to matrix metalloproteinase 14 and transforming growth factor beta-1 (TGFbeta-1).


alpha4-beta1 integrin-JAM2 complex

description: A protein complex that consists of an alpha4-beta1 integrin complex bound to the cell adhesion molecule JAM2.


alpha4-beta1 integrin-paxillin complex

description: A protein complex that consists of an alpha4-beta1 integrin complex bound to paxillin.


DNA conformation change

description: A cellular process that results in a change in the spatial configuration of a DNA molecule. A conformation change can bend DNA, or alter the, twist, writhe, or linking number of a DNA molecule.


response to interleukin-9

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-9 stimulus.


response to interleukin-11

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-11 stimulus.


name: adenosine 3',5'-bisphosphate transmembrane transport

description: The process in which adenosine 3',5'-bisphosphate is transported across a membrane.


response to parathyroid hormone

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a parathyroid hormone stimulus.


protein K48-linked deubiquitination

description: A protein deubiquitination process in which a K48-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 48 of the ubiquitin monomers, is removed from a protein.


superior temporal gyrus development

description: The process whose specific outcome is the progression of the superior temporal gyrus over time, from its formation to the mature structure. The superior temporal gyrus is a portion of the cerebral cortex that extends from the lateral sulcus to the superior temporal sulcus.


description: Catalysis of the reaction: cyclic di-3',5'-guanylate + H2O = 5'-phosphoguanylyl(3'->5')guanosine + H+.


alpha4-beta4 integrin-EMILIN-1 complex

description: A protein complex that consists of an alpha4-beta4 integrin complex bound to EMILIN-1 (ElastinMicrofibril Interface Located ProteIN).


alphaIIb-beta3 integrin-ICAM-4 complex

description: A protein complex that consists of an alphaIIb-beta3 integrin complex bound to the cell adhesion molecule ICAM-4.


alphaV-beta3 integrin-tumstatin complex

description: A protein complex that consists of an alphaV-beta3 integrin complex bound to tumstatin, the NC1 domain of the alpha3 chain of type IV collagen.


description: A protein complex that consists of an alpha5-beta1 integrin complex bound to endostatin, the NC1 domain of the alpha1 chain of type XVIII collagen.


alpha6-beta1 integrin-CYR61 complex

description: A protein complex that consists of an alpha6-beta1 integrin complex bound to CYR61, a cysteine-rich protein involved in angiogenesis.


description: A protein complex that consists of an alpha5-beta1 integrin complex bound to fibronectin and the extracellular matrix protein NOV.


alphaV-beta3 integrin-NOV complex

description: A protein complex that consists of an alphaV-beta3 integrin complex bound to the extracellular matrix protein NOV.


name: alpha7-beta1 integrin-nicotinamide riboside kinase complex

description: A protein complex that consists of an alpha7-beta1 integrin complex bound to nicotinamide riboside kinase 2 (also known as muscle integrin binding protein, MIBP).


alpha4-beta1 integrin-CD47 complex

description: A protein complex that consists of an alpha4-beta1 integrin complex bound to the cell surface antigen CD47.


alpha9-beta1 integrin-VEGF-D complex

description: A protein complex that consists of an alpha9-beta1 integrin complex bound to vascular endothelial growth factor D.


alpha9-beta1 integrin-VEGF-A complex

description: A protein complex that consists of an alpha9-beta1 integrin complex bound to vascular endothelial growth factor A.


alpha9-beta1 integrin-VEGF-C complex

description: A protein complex that consists of an alpha9-beta1 integrin complex bound to vascular endothelial growth factor C.


name: alpha1-beta1 integrin-tyrosine-protein phosphatase non-receptor type 2 complex

description: A protein complex that consists of an alpha1-beta1 integrin complex bound to tyrosine-protein phosphatase non-receptor type 2.


alphaV-beta3 integrin-EGFR complex

description: A protein complex that consists of an alphaV-beta3 integrin complex bound to epidermal growth factor receptor.


description: A protein complex that consists of an alphaV-beta6 integrin complex bound to osteopontin.


description: A protein complex that consists of an alpha9-beta1 integrin complex bound to osteopontin.


description: A protein complex that consists of an alpha5-beta1 integrin complex bound to osteopontin.


alphaV-beta3 integrin-LPP3 complex

description: A protein complex that consists of an alphaV-beta3 integrin complex bound to lipid phosphate phosphohydrolase-3.


alpha5-beta1 integrin-LPP3 complex

description: A protein complex that consists of an alpha5-beta1 integrin complex bound to lipid phosphate phosphohydrolase-3.


name: alphaV-beta3 integrin-laminin alpha-4 complex

description: A protein complex that consists of an alphaV-beta3 integrin complex bound to laminin alpha-4.


alphaX-beta2 integrin-ICAM-4 complex

description: A protein complex that consists of an alphaX-beta2 integrin complex bound to intercellular adhesion molecule 4.


alpha9-beta1 integrin-ADAM8 complex

description: A protein complex that consists of an alpha9-beta1 integrin complex bound to the transmembrane metallopeptidase ADAM8.


description: A protein complex that consists of an alpha9-beta1 integrin complex bound to thrombospondin-1.


name: alpha7-beta1 integrin-focal adhesion kinase complex

description: A protein complex that consists of an alpha7-beta1 integrin complex bound to focal adhesion kinase.


name: alpha7-beta1 integrin-laminin alpha-2 complex

description: A protein complex that consists of an alpha7-beta1 integrin complex bound to laminin alpha-2.


alphaV-beta3 integrin-CD98 complex

description: A protein complex that consists of an alphaV-beta3 integrin complex bound to the cell surface antigen CD98.


alpha5-beta5-fibronectin-SFRP2 complex

description: A protein complex that consists of an alpha5-beta5 integrin complex bound to fibronectin and secreted frizzled-related protein 2.


name: resolution of DNA recombination intermediates

description: The cleavage and rejoining of intermediates, such as Holliday junctions, formed during DNA recombination to produce two intact molecules in which genetic material has been exchanged.


name: resolution of mitotic recombination intermediates

description: The cleavage and rejoining of intermediates, mitotic recombination to produce two intact molecules in which genetic material has been exchanged.


SMAD protein complex

description: A protein complex that consists of only SMAD proteins; may be homomeric or heteromeric. Heteromeric complexes act as transcription factors while homomeric complexes exist but are transcriptionally inactive. Hetero- versus homotrimerization is largely enthalpy driven.


homomeric SMAD protein complex

description: A protein complex composed of a single type of SMAD family proteins. In the absence of Smad4, phosphorylation of R-SMADs results in their homotrimerization. However, these complexes do not appear to import into the nucleus and are assumed to be transcriptionally inactive.


heteromeric SMAD protein complex

description: A protein complex composed of SMAD family proteins, a transcription factor complex which binds to the promoters of target genes and recruits co-activators and histone acetyltransferases, facilitating transcription. Phosphorylation of the non-SMAD4 subunit(s) enables binding of SMAD4 to form heteromeric complexes that enter the nucleus to initiate gene transcription. DNA-binding specificity is conferred by other transcription factors binding to SMAD complexes. Interactions with coactivators or corepressors modulate their transcriptional activity. Can be heterotrimeric or heterodimeric.


G-protein alpha(q)-synembrin complex

description: A protein complex formed by the association of the guanine nucleotide exchange factor synembrin with the alpha(q) subunit of a heterotrimeric G protein.


G-protein alpha(o)-synembrin complex

description: A protein complex formed by the association of the guanine nucleotide exchange factor synembrin with the alpha(o) subunit of a heterotrimeric G protein.


G-protein alpha(i)1-synembrin complex

description: A protein complex formed by the association of the guanine nucleotide exchange factor synembrin with the alpha(i)1 subunit of a heterotrimeric G protein.


G-protein alpha(13)-synembrin complex

description: A protein complex formed by the association of the guanine nucleotide exchange factor synembrin with the alpha(13) subunit of a heterotrimeric G protein.


NF-kappaB complex

description: A protein complex that consists of a homo- or heterodimer of members of a family of structurally related proteins that contain a conserved N-terminal region called the Rel homology domain (RHD). In the nucleus, NF-kappaB complexes act as transcription factors. In unstimulated cells, NF-kappaB dimers are sequestered in the cytoplasm by IkappaB monomers; signals that induce NF-kappaB activity cause degradation of IkappaB, allowing NF-kappaB dimers to translocate to the nucleus and induce gene expression.


name: cyanophycin synthetase activity (L-aspartate-adding)

description: Catalysis of the reaction: ATP + [L-Asp(4-L-Arg)]n + L-Asp = ADP + phosphate + [L-Asp(4-L-Arg)]n-L-Asp.


name: cyanophycin synthetase activity (L-arginine-adding)

description: Catalysis of the reaction: ATP + [L-Asp(4-L-Arg)]n-L-Asp + L-arginine = ADP + phosphate + [L-Asp(4-L-Arg)]n+1.


CMG complex

description: A protein complex that contains the GINS complex, Cdc45p, and the heterohexameric MCM complex, and that is involved in unwinding DNA during replication.


name: DNA replication preinitiation complex assembly

description: The aggregation, arrangement and bonding together of a set of components to form the DNA replication preinitiation complex, a protein-DNA complex that is assembled at DNA replication origins as part of initiation of DNA replication. The complex consists of proteins that initiate the DNA binding, melt the helix and enable helicase activity.


name: RNA cap trimethylguanosine synthase activity

description: Catalysis of two successive methyl transfer reactions from AdoMet to the N-2 atom of guanosine, thereby converting 7-methylguanosine in an RNA cap to 2,2,7 trimethylguanosine.


GINS complex assembly

description: The aggregation, arrangement and bonding together of a set of components to form a GINS complex, a heterotetrameric protein complex that associates with DNA replication origins and replication forks.


ribonucleoprotein complex localization

description: Any process in which a ribonucleoprotein complex is transported to, or maintained in, a specific location within a cell.


protein localization to chromatin

description: Any process in which a protein is transported to, or maintained at, a part of a chromosome that is organized into chromatin.


name: establishment of protein localization to chromatin

description: The directed movement of a protein to a part of a chromosome that is organized into chromatin.


name: site-specific DNA replication termination

description: A DNA replication termination process that takes place at a specific termination site.


name: site-specific DNA replication termination at RTS1 barrier

description: A DNA replication termination process that takes place at the RTS1 termination site in the mating type locus, in a specific direction required for subsequent imprinting and mating-type switching.


dihydromonapterin reductase activity

description: Catalysis of the reaction: 7,8-dihydromonapterin + NADPH = tetrahydromonapterin + NADP+.


spindle assembly checkpoint signaling

category: biolink:Pathway biolink:OntologyClass biolink:BiologicalProcess biolink:Occurrent biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: A signaling process that delays the metaphase/anaphase transition until the spindle is correctly assembled and chromosomes are attached to the spindle.


mitotic spindle checkpoint signaling

description: A signaling process that contributes to a mitotic cell cycle checkpoint that originates from the spindle and delays the metaphase/anaphase transition of a mitotic nuclear division until the spindle is correctly assembled and oriented, the completion of anaphase until chromosomes are attached to the spindle, or mitotic exit and cytokinesis when the spindle does not form.


MAML2-RBP-Jkappa-ICN1 complex

description: A protein complex that consists of the intracellular domain of Notch1 (ICN1), the DNA-binding transcription factor RBP-Jkappa, and the transcriptional coactivator Mastermind-like-2 (MAML2); the complex is involved in transcriptional activation in response to Notch-mediated signaling.


MAML2-RBP-Jkappa-ICN2 complex

description: A protein complex that consists of the intracellular domain of Notch2 (ICN2), the DNA-binding transcription factor RBP-Jkappa, and the transcriptional coactivator Mastermind-like-2 (MAML2); the complex is involved in transcriptional activation in response to Notch-mediated signaling.


MAML2-RBP-Jkappa-ICN3 complex

description: A protein complex that consists of the intracellular domain of Notch3 (ICN3), the DNA-binding transcription factor RBP-Jkappa, and the transcriptional coactivator Mastermind-like-2 (MAML2); the complex is involved in transcriptional activation in response to Notch-mediated signaling.


MAML2-RBP-Jkappa-ICN4 complex

description: A protein complex that consists of the intracellular domain of Notch4 (ICN4), the DNA-binding transcription factor RBP-Jkappa, and the transcriptional coactivator Mastermind-like-2 (MAML2); the complex is involved in transcriptional activation in response to Notch-mediated signaling.


MAML3-RBP-Jkappa-ICN1 complex

description: A protein complex that consists of the intracellular domain of Notch1 (ICN1), the DNA-binding transcription factor RBP-Jkappa, and the transcriptional coactivator Mastermind-like-3 (MAML3); the complex is involved in transcriptional activation in response to Notch-mediated signaling.


MAML3-RBP-Jkappa-ICN2 complex

description: A protein complex that consists of the intracellular domain of Notch2 (ICN2), the DNA-binding transcription factor RBP-Jkappa, and the transcriptional coactivator Mastermind-like-3 (MAML3); the complex is involved in transcriptional activation in response to Notch-mediated signaling.


MAML3-RBP-Jkappa-ICN3 complex

description: A protein complex that consists of the intracellular domain of Notch3 (ICN3), the DNA-binding transcription factor RBP-Jkappa, and the transcriptional coactivator Mastermind-like-3 (MAML3); the complex is involved in transcriptional activation in response to Notch-mediated signaling.


MAML3-RBP-Jkappa-ICN4 complex

description: A protein complex that consists of the intracellular domain of Notch4 (ICN4), the DNA-binding transcription factor RBP-Jkappa, and the transcriptional coactivator Mastermind-like-3 (MAML3); the complex is involved in transcriptional activation in response to Notch-mediated signaling.


description: A protein complex that contains two cell adhesion molecules, a protocadherin-alpha and a protocadherin-gamma, and is involved in the regulation of protein localization to the plasma membrane.


description: A protein complex that contains the cell adhesion molecules protocadherin-alpha-v4 and protocadherin-gamma-a1, and is involved in the regulation of protein localization to the plasma membrane.


description: A protein complex that contains the cell adhesion molecules protocadherin-alpha-v4 and protocadherin-gamma-a3, and is involved in the regulation of protein localization to the plasma membrane.


description: A protein complex that contains the cell adhesion molecules protocadherin-alpha-v4 and protocadherin-gamma-b2, and is involved in the regulation of protein localization to the plasma membrane.


description: A protein complex that contains the cell adhesion molecules protocadherin-alpha-v4 and protocadherin-gamma-b4, and is involved in the regulation of protein localization to the plasma membrane.


description: A protein complex that contains the cell adhesion molecules protocadherin-alpha-v7 and protocadherin-gamma-a1, and is involved in the regulation of protein localization to the plasma membrane.


description: A protein complex that contains the cell adhesion molecules protocadherin-alpha-v7 and protocadherin-gamma-a3, and is involved in the regulation of protein localization to the plasma membrane.


description: A protein complex that contains the cell adhesion molecules protocadherin-alpha-v7 and protocadherin-gamma-b2, and is involved in the regulation of protein localization to the plasma membrane.


description: A protein complex that contains the cell adhesion molecules protocadherin-alpha-v7 and protocadherin-gamma-b4, and is involved in the regulation of protein localization to the plasma membrane.


Kv4.2-KChIP1 channel complex

description: A voltage-gated potassium channel complex that contains the Kv channel interacting protein KChIP1 associated with the channel via interaction with the Kv alpha subunit 4.2.


Kv4.2-KChIP2 channel complex

description: A voltage-gated potassium channel complex that contains the Kv channel interacting protein KChIP2 associated with the channel via interaction with the Kv alpha subunit 4.2.


Kv4.2-KChIP3 channel complex

description: A voltage-gated potassium channel complex that contains the Kv channel interacting protein KChIP3 associated with the channel via interaction with the Kv alpha subunit 4.2.


Kv4.2-KChIP4 channel complex

description: A voltage-gated potassium channel complex that contains the Kv channel interacting protein KChIP4 associated with the channel via interaction with the Kv alpha subunit 4.2.


Kv4.3-KChIP1 channel complex

description: A voltage-gated potassium channel complex that contains the Kv channel interacting protein KChIP1 associated with the channel via interaction with the Kv alpha subunit 4.3.


Kv4.2-Kv4.3 channel complex

description: A voltage-gated potassium channel complex that contains the Kv alpha subunits 4.2 and 4.3.


Kv4.1-DPP6 channel complex

description: A voltage-gated potassium channel complex that contains the peptidase-related protein DPP6 associated with the channel via interaction with the Kv alpha subunit 4.1.


Kv4.1-DPP10 channel complex

description: A voltage-gated potassium channel complex that contains the peptidase-related protein DPP10 associated with the channel via interaction with the Kv alpha subunit 4.1.


Kv4.2-DPP6 channel complex

description: A voltage-gated potassium channel complex that contains the peptidase-related protein DPP6 associated with the channel via interaction with the Kv alpha subunit 4.2.


Kv4.3-DPP6 channel complex

description: A voltage-gated potassium channel complex that contains the peptidase-related protein DPP6 associated with the channel via interaction with the Kv alpha subunit 4.3.


Kv4.3-DPP10 channel complex

description: A voltage-gated potassium channel complex that contains the peptidase-related protein DPP10 associated with the channel via interaction with the Kv alpha subunit 4.3.


WASH complex

description: A protein complex that localizes at the surface of endosomes, where it recruits and activates the Arp2/3 complex to induce actin polymerization. In human, the WASH complex is composed of F-actin-capping protein subunits alpha and beta, WASH1, FAM21, KIAA1033, KIAA0196 and CCDC53.


name: histone pre-mRNA 3'end processing complex

description: A ribonucleoprotein that binds to specific sites in, and is required for cleavage of, the 3'-end of histone pre-mRNAs. The complex contains the U7 snRNP and additional proteins, including the stem-loop binding protein (SLBP) and the exonuclease 3'hExo/Eri-1.


name: protein localization to juxtaparanode region of axon

description: Any process in which a protein is transported to, or maintained at, the juxtaparanode region of an axon.


name: establishment of protein localization to juxtaparanode region of axon

description: The directed movement of a protein to the juxtaparanode region of an axon.


histone pre-mRNA stem-loop binding

description: Binding to a conserved stem-loop structure found in histone pre-mRNAs.


histone pre-mRNA DCP binding

description: Binding to the downstream cleavage product (DCP) generated by histone pre-mRNA 3'-end processing.


U7 snRNA binding

description: Binding to a U7 small nuclear RNA (U7 snRNA).


protein insertion into membrane raft

description: The process in which a protein is incorporated into a membrane raft. Membrane rafts are small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes.


name: protein targeting to vacuole involved in autophagy

description: The process of directing proteins towards the vacuole using signals contained within the protein, occurring as part of autophagy, the process in which cells digest parts of their own cytoplasm.


subsynaptic reticulum

description: An elaborate tubulolamellar membrane system that underlies the postsynaptic cell membrane.


name: cellular response to 1-aminocyclopropane-1-carboxylic acid

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 1-aminocyclopropane-1-carboxylic acid stimulus.


cellular response to abiotic stimulus

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abiotic (non-living) stimulus.


name: cellular response to abscisic acid stimulus

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abscisic acid stimulus.


cellular response to biotic stimulus

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biotic stimulus, a stimulus caused or produced by a living organism.


name: cellular response to external biotic stimulus

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external biotic stimulus, an external stimulus caused by, or produced by living things.


cellular response to misfolded protein

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a misfolded protein stimulus.


name: cellular response to molecule of bacterial origin

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by molecules of bacterial origin such as peptides derived from bacterial flagellin.


name: cellular response to bacterial lipoprotein

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bacterial lipoprotein stimulus.


name: cellular response to bacterial lipopeptide

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bacterial lipopeptide stimulus.


cellular response to lipopolysaccharide

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipopolysaccharide stimulus; lipopolysaccharide is a major component of the cell wall of gram-negative bacteria.


cellular response to lipoteichoic acid

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipoteichoic acid stimulus; lipoteichoic acid is a major component of the cell wall of gram-positive bacteria and typically consists of a chain of glycerol-phosphate repeating units linked to a glycolipid anchor.


cellular response to peptidoglycan

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptidoglycan stimulus. Peptidoglycan is a bacterial cell wall macromolecule.


cellular response to muramyl dipeptide

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a muramyl dipeptide stimulus. Muramyl dipeptide is derived from peptidoglycan.


name: cellular response to molecule of fungal origin

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by molecules of fungal origin such as chito-octamer oligosaccharide.


name: cellular response to molecule of oomycetes origin

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by molecules of oomycetes origin.


cellular response to tumor cell

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a tumor cell.


cellular response to acid chemical

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by the chemical structure of the anion portion of the dissociated acid (rather than the acid acting as a proton donor). The acid chemical may be in gaseous, liquid or solid form.


name: cellular response to amino acid stimulus

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amino acid stimulus. An amino acid is a carboxylic acids containing one or more amino groups.


cellular response to folic acid

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a folic acid stimulus.


cellular response to histidine

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a histidine stimulus.


cellular response to L-leucine

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-leucine stimulus.


cellular response to phenylalanine

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a phenylalanine stimulus.


cellular response to proline

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a proline stimulus.


cellular response to antibiotic

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antibiotic stimulus. An antibiotic is a chemical substance produced by a microorganism which has the capacity to inhibit the growth of or to kill other microorganisms.


cellular response to bacteriocin

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bacteriocin stimulus. A bacteriocin is a protein substance released by certain bacteria that kills but does not lyse closely related strains of bacteria. Specific bacteriocins attach to specific receptors on cell walls and induce specific metabolic block, e.g. cessation of nucleic acid or protein synthesis of oxidative phosphorylation.


cellular response to brefeldin A

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a brefeldin A stimulus.


cellular response to streptomycin

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a streptomycin stimulus. Streptomycin is a commonly used antibiotic in cell culture media which acts only on prokaryotes and blocks transition from initiation complex to chain elongating ribosome.


cellular response to food

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a food stimulus; food is anything which, when taken into the body, serves to nourish or build up the tissues or to supply body heat.


cellular response to ammonium ion

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ammonium stimulus.


name: cellular response to arsenic-containing substance

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an arsenic stimulus from compounds containing arsenic, including arsenates, arsenites, and arsenides.


cellular response to carbon dioxide

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbon dioxide (CO2) stimulus.


cellular response to carbon monoxide

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbon monoxide (CO) stimulus.


cellular response to chlorate

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chlorate stimulus.


cellular response to chromate

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chromate stimulus.


cellular response to metal ion

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a metal ion stimulus.


cellular response to nitrate

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrate stimulus.


cellular response to nitrite

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrite stimulus.


cellular response to silicon dioxide

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a silicon dioxide stimulus.


cellular response to sulfur dioxide

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sulfur dioxide (SO2) stimulus.


connexin binding

description: Binding to a connexin, any of a group of related proteins that assemble to form gap junctions.


cytoplasmic U snRNP body

description: A ribonucleoprotein complex that can be visualized as a focus in the cytoplasm, and contains uridine-rich small nuclear ribonucleoproteins (U snRNPs) and essential snRNP assembly factors. These U bodies are invariably found in association with P bodies.


Cvt vesicle assembly

description: A vesicle organization process that takes place as part of the Cvt pathway, and results in the formation of a double membrane-bounded cytosolic structure that sequesters precursor aminopeptidase I (prAPI).


translocon complex

description: A protein complex that constitutes a specific site of protein translocation across the endoplasmic reticulum, which involves the signal recognition particle receptor. The complex contains a core heterotrimer of alpha, beta and gamma subunits, and may contain additional proteins.


name: cellular response to electrical stimulus

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electrical stimulus.


cellular response to gravity

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gravitational stimulus.


cellular response to magnetism

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a magnetic stimulus.


name: cellular response to mechanical stimulus

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mechanical stimulus.


Ssh1 translocon complex

description: A translocon complex that contains a core heterotrimer of alpha, beta and gamma subunits, and may contain additional proteins (translocon-associated proteins or TRAPs); in budding yeast the core proteins are Ssh1p, Sbh2p, and Sss1p. The Ssh1 translocon complex is involved in the cotranslational pathway of protein transport across the ER membrane, and recognizes proteins bearing strongly hydrophobic signal sequences.


name: regulation of translational initiation in response to starvation

description: Any process that modulates the frequency, rate or extent of translation initiation, as a result of deprivation of nourishment.


name: negative regulation of translational initiation in response to starvation

description: Any process that stops, prevents or reduces the rate of translation initiation, as a result of deprivation of nourishment.